Sample records for total plasma density

  1. Device for plasma confinement and heating by high currents and nonclassical plasma transport properties

    DOEpatents

    Coppi, B.; Montgomery, D.B.

    1973-12-11

    A toroidal plasma containment device having means for inducing high total plasma currents and current densities and at the same time emhanced plasma heating, strong magnetic confinement, high energy density containment, magnetic modulation, microwaveinduced heating, and diagnostic accessibility is described. (Official Gazette)

  2. Triglycerides, total cholesterol, high density lipoprotein cholesterol and low density lipoprotein cholesterol in rats exposed to premium motor spirit fumes.

    PubMed

    Aberare, Ogbevire L; Okuonghae, Patrick; Mukoro, Nathaniel; Dirisu, John O; Osazuwa, Favour; Odigie, Elvis; Omoregie, Richard

    2011-06-01

    Deliberate and regular exposure to premium motor spirit fumes is common and could be a risk factor for liver disease in those who are occupationally exposed. A possible association between premium motor spirit fumes and plasma levels of triglyceride, total cholesterol, high density lipoprotein cholesterol and low density lipoprotein cholesterol using a rodent model could provide new insights in the pathology of diseases where cellular dysfunction is an established risk factor. The aim of this study was to evaluate the possible effect of premium motor spirit fumes on lipids and lipoproteins in workers occupationally exposed to premium motor spirit fumes using rodent model. Twenty-five Wister albino rats (of both sexes) were used for this study between the 4(th) of August and 7(th) of September, 2010. The rats were divided into five groups of five rats each. Group 1 rats were not exposed to premium motor spirit fumes (control group), group 2 rats were exposed for 1 hour daily, group 3 for 3 hours daily, group 4 for 5 hours daily and group 5 for 7 hours daily. The experiment lasted for a period of 4 weeks. Blood samples obtained from all the groups after 4 weeks of exposure were used for the estimation of plasma levels of triglyceride, total cholesterol, high density lipoprotein- cholesterol and low density lipoprotein- cholesterol. Results showed significant increase in means of plasma total cholesterol and low density lipoprotein levels (P<0.05). The mean triglyceride and total body weight were significantly lower (P<0.05) in the exposed group when compared with the unexposed. The plasma level of high density lipoprotein, the ratio of low density lipoprotein to high density lipoprotein and the ratio of total cholesterol to high density lipoprotein did not differ significantly in exposed subjects when compared with the control group. These results showed that frequent exposure to petrol fumes may be highly deleterious to the liver cells.

  3. A New Global Core Plasma Model of the Plasmasphere

    NASA Technical Reports Server (NTRS)

    Gallagher, D. L.; Comfort, R. H.; Craven, P. D.

    2014-01-01

    The Global Core Plasma Model (GCPM) is the first empirical model for thermal inner magnetospheric plasma designed to integrate previous models and observations into a continuous in value and gradient representation of typical total densities. New information about the plasmasphere, in particular, make possible significant improvement. The IMAGE Mission Radio Plasma Imager (RPI) has obtained the first observations of total plasma densities along magnetic field lines in the plasmasphere and polar cap. Dynamics Explorer 1 Retarding Ion Mass Spectrometer (RIMS) has provided densities in temperatures in the plasmasphere for 5 ion species. These and other works enable a new more detailed empirical model of thermal in the inner magnetosphere that will be presented. Specifically shown here are the inner-plasmasphere RIMS measurements, radial fits to densities and temperatures for H(+), He(+), He(++), O(+), and O(+) and the error associated with these initial simple fits. Also shown are more subtle dependencies on the f10.7 P-value (see Richards et al. [1994]).

  4. Ghrelin plasma levels, gastric ghrelin cell density and bone mineral density in women with rheumatoid arthritis

    PubMed Central

    Maksud, F.A.N.; Kakehasi, A.M.; Guimarães, M.F.B.R.; Machado, C.J.; Barbosa, A.J.A.

    2017-01-01

    Generalized bone loss can be considered an extra-articular manifestation of rheumatoid arthritis (RA) that may lead to the occurrence of fractures, resulting in decreased quality of life and increased healthcare costs. The peptide ghrelin has demonstrated to positively affect osteoblasts in vitro and has anti-inflammatory actions, but the studies that correlate ghrelin plasma levels and RA have contradictory results. We aimed to evaluate the correlation between total ghrelin plasma levels, density of ghrelin-immunoreactive cells in the gastric mucosa, and bone mineral density (BMD) in twenty adult women with established RA with 6 months or more of symptoms (mean age of 52.70±11.40 years). Patients with RA presented higher ghrelin-immunoreactive cells density in gastric mucosa (P=0.008) compared with healthy females. There was a positive relationship between femoral neck BMD and gastric ghrelin cell density (P=0.007). However, these same patients presented a negative correlation between plasma ghrelin levels and total femoral BMD (P=0.03). The present results indicate that ghrelin may be involved in bone metabolism of patients with RA. However, the higher density of ghrelin-producing cells in the gastric mucosa of these patients does not seem to induce a corresponding elevation in the plasma levels of this peptide. PMID:28538835

  5. Ghrelin plasma levels, gastric ghrelin cell density and bone mineral density in women with rheumatoid arthritis.

    PubMed

    Maksud, F A N; Kakehasi, A M; Guimarães, M F B R; Machado, C J; Barbosa, A J A

    2017-05-18

    Generalized bone loss can be considered an extra-articular manifestation of rheumatoid arthritis (RA) that may lead to the occurrence of fractures, resulting in decreased quality of life and increased healthcare costs. The peptide ghrelin has demonstrated to positively affect osteoblasts in vitro and has anti-inflammatory actions, but the studies that correlate ghrelin plasma levels and RA have contradictory results. We aimed to evaluate the correlation between total ghrelin plasma levels, density of ghrelin-immunoreactive cells in the gastric mucosa, and bone mineral density (BMD) in twenty adult women with established RA with 6 months or more of symptoms (mean age of 52.70±11.40 years). Patients with RA presented higher ghrelin-immunoreactive cells density in gastric mucosa (P=0.008) compared with healthy females. There was a positive relationship between femoral neck BMD and gastric ghrelin cell density (P=0.007). However, these same patients presented a negative correlation between plasma ghrelin levels and total femoral BMD (P=0.03). The present results indicate that ghrelin may be involved in bone metabolism of patients with RA. However, the higher density of ghrelin-producing cells in the gastric mucosa of these patients does not seem to induce a corresponding elevation in the plasma levels of this peptide.

  6. Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

    USDA-ARS?s Scientific Manuscript database

    Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholest...

  7. Formation of Ion Beam from High Density Plasma of ECR Discharge

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Izotov, I.; Razin, S.; Sidorov, A.

    2005-03-15

    One of the most promising directions of ECR multicharged ion sources evolution is related with increase in frequency of microwave pumping. During last years microwave generators of millimeter wave range - gyrotrons have been used more frequently. Creation of plasma with density 1013 cm-3 with medium charged ions and ion flux density through a plug of a magnetic trap along magnetic field lines on level of a few A/cm2 is possible under pumping by powerful millimeter wave radiation and quasigasdynamic (collisional) regime of plasma confinement in the magnetic trap. Such plasma has great prospects for application in plasma based ionmore » implantation systems for processing of surfaces with complicated and petit relief. Use it for ion beam formation seams to be difficult because of too high ion current density. This paper continues investigations described elsewhere and shows possibility to arrange ion extraction in zone of plasma expansion from the magnetic trap along axis of system and magnetic field lines.Plasma was created at ECR gas discharge by means of millimeter wave radiation of a gyrotron with frequency 37.5 GHz, maximum power 100 kW, pulse duration 1.5 ms. Two and three electrode quasi-Pierce extraction systems were used for ion beam formation.It is demonstrated that there is no changes in ion charge state distribution along expansion routing of plasma under collisional confinement. Also ion flux density decreases with distance from plug of the trap, it allows to control extracting ion current density. Multicharged ion beam of Nitrogen with total current up to 2.5 mA at diameter of extracting hole 1 mm, that corresponds current density 320 mA/cm2, was obtained. Magnitude of total ion current was limited due to extracting voltage (60 kV). Under such conditions characteristic transversal dimension of plasma equaled 4 cm, magnetic field value in extracting zone was about 0.1 T at axisymmetrical configuration.« less

  8. Comparison of plasma levels of obesity-related biomarkers among Japanese populations in Tokyo, Japan, São Paulo, Brazil, and Hawaii, USA.

    PubMed

    Iwasaki, Motoki; Le Marchand, Loïc; Franke, Adrian A; Hamada, Gerson Shigeaki; Miyajima, Nelson Tomio; Sharma, Sangita; Yamaji, Taiki; Tsugane, Shoichiro

    2016-01-01

    Although Japanese in Japan and the USA are high-risk populations for colorectal cancer, the prevalence of obesity, one of the established risk factors for this disease, is low in these populations compared with other high-risk populations. To understand this inconsistency, we compared plasma obesity-related biomarkers in cross-sectional studies carried out in Tokyo, São Paulo, and Hawaii. We measured plasma levels of insulin-like growth factor-I (IGF-I), insulin-like growth factor-binding protein (IGFBP)-1, IGFBP-3, C-peptide, adiponectin, leptin, tumor necrosis factor-α, and interleukin-6 by immunoassay and total C-reactive protein, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and triglycerides using a clinical chemistry autoanalyzer. A total of 299 participants were included in the present analysis, comprising 142 Japanese in Tokyo, 79 Japanese Brazilians in São Paulo, and 78 Japanese Americans in Hawaii. We found significantly lower plasma levels of C-peptide and IGF-I in Japanese in Tokyo than in Japanese Americans, and lower levels of leptin and triglycerides and higher levels of adiponectin, IGFBP-3, and high-density lipoprotein cholesterol in Japanese in Tokyo than in the other two populations. We also observed a significantly higher plasma IGFBP-1 level in Japanese Brazilians, and lower plasma levels of total cholesterol and low-density lipoprotein in Japanese Americans than in the other two populations. We observed significant differences in obesity-related biomarkers between the three Japanese populations. If our results are confirmed, the risk of colorectal cancer predicted on the basis of these biomarkers would be lowest for Japanese in Tokyo, followed by Japanese Brazilians and Japanese Americans.

  9. Comparison of plasma levels of obesity-related biomarkers among Japanese populations in Tokyo, Japan, São Paulo, Brazil, and Hawaii, USA

    PubMed Central

    Le Marchand, Loïc; Franke, Adrian A.; Hamada, Gerson Shigeaki; Miyajima, Nelson Tomio; Sharma, Sangita; Yamaji, Taiki; Tsugane, Shoichiro

    2016-01-01

    Although Japanese in Japan and the USA are high-risk populations for colorectal cancer, the prevalence of obesity, one of the established risk factors for this disease, is low in these populations compared with other high-risk populations. To understand this inconsistency, we compared plasma obesity-related biomarkers in cross-sectional studies carried out in Tokyo, São Paulo, and Hawaii. We measured plasma levels of insulin-like growth factor-I (IGF-I), insulin-like growth factor-binding protein (IGFBP)-1, IGFBP-3, C-peptide, adiponectin, leptin, tumor necrosis factor-α, and interleukin-6 by immunoassay and total C-reactive protein, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and triglycerides using a clinical chemistry autoanalyzer. A total of 299 participants were included in the present analysis, comprising 142 Japanese in Tokyo, 79 Japanese Brazilians in São Paulo, and 78 Japanese Americans in Hawaii. We found significantly lower plasma levels of C-peptide and IGF-I in Japanese in Tokyo than in Japanese Americans, and lower levels of leptin and triglycerides and higher levels of adiponectin, IGFBP-3, and high-density lipoprotein cholesterol in Japanese in Tokyo than in the other two populations. We also observed a significantly higher plasma IGFBP-1 level in Japanese Brazilians, and lower plasma levels of total cholesterol and low-density lipoprotein in Japanese Americans than in the other two populations. We observed significant differences in obesity-related biomarkers between the three Japanese populations. If our results are confirmed, the risk of colorectal cancer predicted on the basis of these biomarkers would be lowest for Japanese in Tokyo, followed by Japanese Brazilians and Japanese Americans. PMID:25714650

  10. Enrichment of plasma membrane proteins using nanoparticle pellicles: comparison between silica and higher density nanoparticles

    PubMed Central

    Choksawangkarn, Waeowalee; Kim, Sung-Kyoung; Cannon, Joe R.; Edwards, Nathan J.; Lee, Sang Bok; Fenselau, Catherine

    2013-01-01

    Proteomic and other characterization of plasma membrane proteins is made difficult by their low abundance, hydrophobicity, frequent carboxylation and dynamic population. We and others have proposed that underrepresentation in LC-MS/MS analysis can be partially compensated by enriching the plasma membrane and its proteins using cationic nanoparticle pellicles. The nanoparticles increase the density of plasma membrane sheets and thus enhance separation by centrifugation from other lysed cellular components. Herein we test the hypothesis that the use of nanoparticles with increased densities can provide enhanced enrichment of plasma membrane proteins for proteomic analysis. Multiple myeloma cells were grown and coated in suspension with three different pellicles of three different densities and both pellicle coated and uncoated suspensions analyzed by high-throughput LC-MS/MS. Enrichment was evaluated by the total number and the spectral counts of identified plasma membrane proteins. PMID:23289353

  11. Behavior of moving plasma in solenoidal magnetic field in a laser ion source

    NASA Astrophysics Data System (ADS)

    Ikeda, S.; Takahashi, K.; Okamura, M.; Horioka, K.

    2016-02-01

    In a laser ion source, a solenoidal magnetic field is useful to guide the plasma and to control the extracted beam current. However, the behavior of the plasma drifting in the magnetic field has not been well understood. Therefore, to investigate the behavior, we measured the plasma ion current and the total charge within a single pulse in the solenoid by changing the distance from the entrance of the solenoid to a detector. We observed that the decrease of the total charge along the distance became smaller as the magnetic field became larger and then the charge became almost constant with a certain magnetic flux density. The results indicate that the transverse spreading speed of the plasma decreased with increasing the field and the plasma was confined transversely with the magnetic flux density. We found that the reason of the confinement was not magnetization of ions but an influence induced by electrons.

  12. Behavior of moving plasma in solenoidal magnetic field in a laser ion source.

    PubMed

    Ikeda, S; Takahashi, K; Okamura, M; Horioka, K

    2016-02-01

    In a laser ion source, a solenoidal magnetic field is useful to guide the plasma and to control the extracted beam current. However, the behavior of the plasma drifting in the magnetic field has not been well understood. Therefore, to investigate the behavior, we measured the plasma ion current and the total charge within a single pulse in the solenoid by changing the distance from the entrance of the solenoid to a detector. We observed that the decrease of the total charge along the distance became smaller as the magnetic field became larger and then the charge became almost constant with a certain magnetic flux density. The results indicate that the transverse spreading speed of the plasma decreased with increasing the field and the plasma was confined transversely with the magnetic flux density. We found that the reason of the confinement was not magnetization of ions but an influence induced by electrons.

  13. Applied axial magnetic field effects on laboratory plasma jets: Density hollowing, field compression, and azimuthal rotation

    DOE PAGES

    Byvank, T.; Banasek, J. T.; Potter, W. M.; ...

    2017-12-07

    We experimentally measure the effects of an applied axial magnetic field (B z) on laboratory plasma jets and compare experimental results with numerical simulations using an extended magnetohydrodynamics code. A 1 MA peak current, 100 ns rise time pulse power machine is used to generate the plasma jet. On application of the axial field, we observe on-axis density hollowing and a conical formation of the jet using interferometry, compression of the applied B z using magnetic B-dot probes, and azimuthal rotation of the jet using Thomson scattering. Experimentally, we find densities ≤ 5×10 17 cm -3 on-axis relative to jetmore » densities of ≥ 3×10 18 cm -3. For aluminum jets, 6.5 ± 0.5 mm above the foil, we find on-axis compression of the applied 1.0 ± 0.1 T B z to a total 2.4 ± 0.3 T, while simulations predict a peak compression to a total 3.4 T at the same location. On the aluminum jet boundary, we find ion azimuthal rotation velocities of 15-20 km/s, while simulations predict 14 km/s at the density peak. We discuss possible sources of discrepancy between the experiments and simulations, including: surface plasma on B-dot probes, optical fiber spatial resolution, simulation density floors, and 2D vs. 3D simulation effects. Lastly, this quantitative comparison between experiments and numerical simulations helps elucidate the underlying physics that determine the plasma dynamics of magnetized plasma jets.« less

  14. Applied axial magnetic field effects on laboratory plasma jets: Density hollowing, field compression, and azimuthal rotation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Byvank, T.; Banasek, J. T.; Potter, W. M.

    We experimentally measure the effects of an applied axial magnetic field (B z) on laboratory plasma jets and compare experimental results with numerical simulations using an extended magnetohydrodynamics code. A 1 MA peak current, 100 ns rise time pulse power machine is used to generate the plasma jet. On application of the axial field, we observe on-axis density hollowing and a conical formation of the jet using interferometry, compression of the applied B z using magnetic B-dot probes, and azimuthal rotation of the jet using Thomson scattering. Experimentally, we find densities ≤ 5×10 17 cm -3 on-axis relative to jetmore » densities of ≥ 3×10 18 cm -3. For aluminum jets, 6.5 ± 0.5 mm above the foil, we find on-axis compression of the applied 1.0 ± 0.1 T B z to a total 2.4 ± 0.3 T, while simulations predict a peak compression to a total 3.4 T at the same location. On the aluminum jet boundary, we find ion azimuthal rotation velocities of 15-20 km/s, while simulations predict 14 km/s at the density peak. We discuss possible sources of discrepancy between the experiments and simulations, including: surface plasma on B-dot probes, optical fiber spatial resolution, simulation density floors, and 2D vs. 3D simulation effects. Lastly, this quantitative comparison between experiments and numerical simulations helps elucidate the underlying physics that determine the plasma dynamics of magnetized plasma jets.« less

  15. Influence of the electron density on the characteristics of terahertz waves generated under laser–cluster interaction

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Frolov, A. A., E-mail: frolov@ihed.ras.ru

    2016-12-15

    A theory of generation of terahertz radiation under laser–cluster interaction, developed earlier for an overdense cluster plasma [A. A. Frolov, Plasma Phys. Rep. 42. 637 (2016)], is generalized for the case of arbitrary electron density. The spectral composition of radiation is shown to substantially depend on the density of free electrons in the cluster. For an underdense cluster plasma, there is a sharp peak in the terahertz spectrum at the frequency of the quadrupole mode of a plasma sphere. As the electron density increases to supercritical values, this spectral line vanishes and a broad maximum at the frequency comparable withmore » the reciprocal of the laser pulse duration appears in the spectrum. The dependence of the total energy of terahertz radiation on the density of free electrons is analyzed. The radiation yield is shown to increase significantly under resonance conditions, when the laser frequency is close to the eigenfrequency of the dipole or quadrupole mode of a plasma sphere.« less

  16. The role of plasma density scale length on the laser pulse propagation and scattering in relativistic regime

    NASA Astrophysics Data System (ADS)

    Pishdast, Masoud; Ghasemi, Seyed Abolfazl; Yazdanpanah, Jamal Aldin

    2017-10-01

    The role of plasma density scale length on two short and long laser pulse propagation and scattering in under dense plasma have been investigated in relativistic regime using 1 D PIC simulation. In our simulation, different density scale lengths and also two short and long pulse lengths with temporal pulse duration τL = 60 fs and τL = 300 fs , respectively have been used. It is found that laser pulse length and density scale length have considerable effects on the energetic electron generation. The analysis of total radiation spectrum reveals that, for short laser pulses and with reducing density scale length, more unstable electromagnetic modes grow and strong longitudinal electric field generates which leads to the generation of more energetic plasma particles. Meanwhile, the dominant scattering mechanism is Raman scattering and tends to Thomson scattering for longer laser pulse.

  17. Investigation of mid-latitude electron density enhancement using total electron content measurements and FORMOSAT-3/COSMIC electron density profiles

    NASA Astrophysics Data System (ADS)

    Rajesh, P. K.; Nanan, Balan; Liu, Jann-Yenq; Lin, Charles C. H.; Chang, S. Y.; Chen, Chia-Hung

    This study investigates the mid-latitude electron density enhancement (MEDE) using global ionospheric map (GIM) total electron content (TEC) measurements and FORMOSAT-3/COSMIC (F3/C) electron density profiles. Diurnal, seasonal, latitudinal, and solar activity variations in the occurrence and strength of MEDE are examined using global GIM TEC data in the years 2002 and 2009. The results show that MEDE occurrence is pronounced during 2200-0400 LT, the feature also appears during day. The strength of MEDE maximizes around 0400 LT, and is very weak during daytime. The occurrence and strength show significant longitude dependence, and vary with season and solar activity. Concurrent F3/C electron density profiles also reveal enhancement of the peak electron density and total electron content. Further studies are carried out by examining the role of neutral wind in re-organizing the plasma using SAMI2 and HWM93 models. The results indicate that meridional neutral wind could cause the plasma to converge over mid-latitudes, and thus support in maintaining the enhancement.

  18. Anti-atherogenic effect of chromium picolinate in streptozotocin-induced experimental diabetes.

    PubMed

    Sundaram, Bhuvaneshwari; Singhal, Kirti; Sandhir, Rajat

    2013-03-01

    Several studies have implicated changes in the levels of trace elements in diabetes. Chromium is one such element that seems to potentiate insulin action, thereby regulating carbohydrate and lipid metabolism. The aim of the present study was to evaluate the effect of chromium supplementation as chromium picolinate on the lipid profile of streptozotocin (STZ)-induced diabetic rats. Rats were rendered diabetic by a single injection of STZ (50 mg/kg, i.p.). Chromium picolinate (1 mg/kg per day, p.o.) was administered to rats for a period of 4 weeks. At the end of the treatment period, plasma total lipids, triglycerides, total cholesterol and lipoprotein levels were determined, as was hepatic glucose-6-phosphate dehydrogenase activity. Total plasma lipids increased significantly in diabetic rats and this increase was ameliorated by chromium treatment for 4 weeks. Elevated total lipids in diabetic rats were due to increased plasma triglyceride and cholesterol levels. Chromium supplementation lowered plasma triglyceride and cholesterol levels to near normal. Chromium treatment also normalized low-density lipoprotein-cholesterol (LDL-C) and very low-density lipoprotein-cholesterol levels and improved the total cholesterol:high-density lipoprotein-cholesterol (HDL-C) and HDL-C:LDL-C ratios, suggesting an anti-atherogenic effect. In addition to improving the plasma lipid profile, chromium supplementation normalized liver glucose-6-phosphate dehydrogenase activity in diabetic rats. These results provide evidence that chromium picolinate effectively attenuates the dyslipidemia associated with diabetes and thus can be used as an adjuvant therapy in the treatment of diabetes and its associated complications. © 2012 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and Wiley Publishing Asia Pty Ltd.

  19. Global power balance on high density field reversed configurations for use in magnetized target fusion

    NASA Astrophysics Data System (ADS)

    Renneke, Richard M.

    Field Reversed Configuration plasmas (FRCs) have been created in the Field Reversed Experiment-Liner (FRX-L) with density 2--6 x 10 22 m-3, total temperature 300--400 eV, and lifetime on the order of 10 micros. This thesis investigates global energy balance on high-density FRCs for the first time. The zero-dimensional approach to global energy balance developed by Rej and Tuszewski (Phys. Fluids 27, p. 1514, 1984) is utilized here. From the shots analyzed with this method, it is clear that energy loss from these FRCs is dominated by particle and thermal (collisional) losses. The percentage of radiative losses versus total loss is an order of magnitude lower than previous FRC experiments. This is reasonable for high density based on empirical scaling from the extensive database of tokamak plasma experiments. Ohmic dissipation, which heats plasma when trapped magnetic field decays to create electric field, is an important source of heating for the plasma. Ohmic heating shows a correlation with increasing the effective Lundquist number (S*). Empirical evidence suggest S* can be increased by lowering the density, which does not achieve the goals of FRX-L. A better way to improve ohmic heating is to trap more poloidal flux. This dissertation shows that FRX-L follows a semi-empirical scaling law which predicts plasma temperature gains for larger poloidal flux. Flux (tauφ) and particle (tauN) lifetimes for these FRCs were typically shorter than 10 micros. Approximately 1/3 of the particle and flux lifetimes for these FRCs did not scale with the usual tauN ≈ tauφ scaling of low-density FRCs, but instead showed tauN ≥ tau φ. However, scatter in the data indicates that the average performance of FRCs on FRX-L yields the typical (for FRCs) relationship tau N ≈ tauφ. Fusion energy gain Q was extrapolated for the shots analyzed in this study using a zero-dimensional scaling code with liner effects. The predicted Q is below the desired value of 0.1 (Schoenberg et al., LA-UR-98-2413, 1998). The situation predicted to lead to Q = 0.1 requires a larger plasma pressure than shown in the present data. This can be accomplished by increasing the plasma density (through larger fill pressure) and maintaining temperature with increased flux trapping. Larger Q and other benefits could be realized by raising the plasma pressure for future FRX-L shots. The innovation inherent in this work performed by the author is the extension of the global power balance model to include a time history of the plasma discharge. This extension required rigorous checking of the power balance model using internal density profiles provided by the multichord interferometer. Typical orders of the parameters calculated by the model are ˜500 MW total loss power, ˜100 MW ohmic heating power, and ˜200 MW total compression (input) power. Radiation was never measured above 5 MW, which is why it was deemed insignificant. It should be noted that these numbers are merely estimates and vary widely between shots.

  20. Appraisal of Antihyperlipidemic Activities of Lentinus lepideus in Hypercholesterolemic Rats

    PubMed Central

    Yoon, Ki Nam; Lee, Jae Seong; Kim, Hye Young; Lee, Kyung Rim; Shin, Pyung Gyun; Cheong, Jong Chun; Yoo, Young Bok; Alam, Nuhu; Ha, Tai Moon

    2011-01-01

    The wild edible mushroom, Lentinus lepideus has recently been cultivated for commercial use in Korea. While the mushroom has been widely used for nutritional and medicinal purposes, the possible anti-hyperlipidemic action is unclear. The effects of dietary L. lepideus on plasma and feces biochemical and on the liver histological status were investigated in hypercholesterolemic rats. Six-wk-old female Sprague-Dawley albino rats were divided into three groups of 10 rats each. Biochemical and histological examinations were performed. A diet containing 5% L. lepideus fruiting bodies reduced plasma total cholesterol, triglyceride, low-density lipoprotein, total lipid, phospholipids, and the ratio of low-density to high-density lipoprotein. Body weight was reduced. The diet did not adversely affect plasma biochemical and enzyme profiles. L. lepideus reduced significantly plasma β- and pre-β-lipoprotein, while α-lipoprotein content was increased. A histological study of hepatic cells by conventional hematoxylin-eosin and oil red O staining revealed normal findings for mushroom-fed hypercholesterolemic rats. The present study suggests that a diet supplemented with L. lepideus can provide health benefits by acting on the atherogenic lipid profile in hypercholesterolemic rats. PMID:22783117

  1. Coupled low-energy - ring current plasma diffusion in the Jovian magnetosphere

    NASA Technical Reports Server (NTRS)

    Summers, D.; Siscoe, G. L.

    1985-01-01

    The outwardly diffusing Iogenic plasma and the simultaneously inwardly diffusing ring current plasma in the Jovian magnetosphere are described using a coupled diffusion model which incorporates the effects of the pressure gradient of the ring current into the cross-L diffusion coefficient. The coupled diffusion coefficient is derived by calculating the total energy available to drive the diffusion process. The condition is imposed that the diffusion coefficient takes on a local minimum value at some point in the region L = 7-8, at which point the gradient of the Io plasma density is specified as ramp value given by Siscoe et al. (1981). The hypothesis that the pressure gradient of the ring current causes the diminution of radial plasma transport is tested, and solution profiles for the Iogenic and ring current plasma densities are obtained which imply that the Io plasma ramp is caused by a high-density, low-energy component of the ring current hitherto unobserved directly.

  2. Modeling the total dust production of Enceladus from stochastic charge equilibrium and simulations

    NASA Astrophysics Data System (ADS)

    Meier, Patrick; Motschmann, Uwe; Schmidt, Jürgen; Spahn, Frank; Hill, Thomas W.; Dong, Yaxue; Jones, Geraint H.; Kriegel, Hendrik

    2015-12-01

    Negatively and positively charged nano-sized ice grains were detected in the Enceladus plume by the Cassini Plasma Spectrometer (CAPS). However, no data for uncharged grains, and thus for the total amount of dust, are available. In this paper we estimate this population of uncharged grains based on a model of stochastic charging in thermodynamic equilibrium and on the assumption of quasi-neutrality in the plasma-dust system. This estimation is improved upon by combining simulations of the dust component of the plume and simulations for the plasma environment into one self-consistent model. Calibration of this model with CAPS data provides a total dust production rate of about 12 kg s-1, including larger dust grains up to a few microns in size. We find that the fraction of charged grains dominates over that of the uncharged grains. Moreover, our model reproduces densities of both negatively and positively charged nanograins measured by Cassini CAPS. In Enceladus' plume ion densities up to ~104cm-3 are required by the self-consistent model, resulting in an electron depletion of about 50% in the plasma, because electrons are attached to the negatively charged nanograins. These ion densities correspond to effective ionization rates of about 10-7s-1, which are about two orders of magnitude higher than expected.

  3. UCB current detector experiment on Swedish auroral payloads. [ionospheric current and plasma flow measurements

    NASA Technical Reports Server (NTRS)

    Mozer, F.

    1974-01-01

    A split Langmuir probe has been developed to make in situ measurements of ionospheric current density and plasma bulk flow. The probe consists of two conducting elements that are separated by a thin insulator that shield each other over a 2 pi solid angle, and that are simultaneously swept from negative to positive with respect to the plasma. By measuring the current to each plate and the difference current between plates, information is obtained on the plasma's current density, bulk flow, electron temperature, and density. The instrument was successfully flown twice on sounding rockets into auroral events. Measurement data indicate that the total auroral current configuration is composed of several alternating east and west electrojets associated with several alternating up and down Birkeland currents.

  4. Correcting magnetic probe perturbations on current density measurements of current carrying plasmas.

    PubMed

    Knoblauch, P; Raspa, V; Di Lorenzo, F; Lazarte, A; Clausse, A; Moreno, C

    2010-09-01

    A method to infer the current density distribution in the current sheath of a plasma focus discharge from a magnetic probe is formulated and then applied to experimental data obtained in a 1.1 kJ device. Distortions on the magnetic probe signal caused by current redistribution and by a time-dependent total discharge current are considered simultaneously, leading to an integral equation for the current density. Two distinct, easy to implement, numerical procedures are given to solve such equation. Experimental results show the coexistence of at least two maxima in the current density structure of a nitrogen sheath.

  5. Spectra from pair-equilibrium plasmas

    NASA Technical Reports Server (NTRS)

    Zdziarski, A. A.

    1984-01-01

    A numerical model of relativistic nonmagnetized plasma with uniform temperature and electron density distributions is considered, and spectra from plasma in pair equilibrium are studied. A range of dimensionless temperature (T) greater than about 0.2 is considered. The spectra from low pair density plasmas in pair equilibrium vary from un-Comptonized bremsstrahlung spectra at Thomson cross section tau(N) much less than one to Comptonized bremsstrahlung spectra with tau(N) over one. For high pair density plasmas the spectra are flat for T greater than about one, and have broad intensity peaks at energy roughly equal to 3T for T less than one. In the latter region the total luminosity is approximately twice the annihilation luminosity. All spectra are flat in the X-ray region, in contradiction to observed AGN spectra. For dimensionless luminosity greater than about 100, the cooling time becomes shorter than the Thomson time.

  6. Ursolic acid and luteolin-7-glucoside improve lipid profiles and increase liver glycogen content through glycogen synthase kinase-3.

    PubMed

    Azevedo, Marisa F; Camsari, Cagri; Sá, Carla M; Lima, Cristovao F; Fernandes-Ferreira, Manuel; Pereira-Wilson, Cristina

    2010-06-01

    In the present study, two phytochemicals - ursolic acid (UA) and luteolin-7-glucoside (L7G) - were assessed in vivo in healthy rats regarding effects on plasma glucose and lipid profile (total cholesterol, HDL and LDL), as well as liver glycogen content, in view of their importance in the aetiology of diabetes and associated complications. Both UA and L7G significantly decreased plasma glucose concentration. UA also significantly increased liver glycogen levels accompanied by phosphorylation of glycogen synthase kinase-3 (GSK3). The increase in glycogen deposition induced by UA (mediated by GSK3) could have contributed to the lower plasma glucose levels observed. Both compounds significantly lowered total plasma cholesterol and low-density lipoprotein levels, and, in addition, UA increased plasma high-density lipoprotein levels. Our results show that UA particularly may be useful in preventable strategies for people at risk of developing diabetes and associated cardiovascular complications by improving plasma glucose levels and lipid profile, as well as by promoting liver glycogen deposition.

  7. Elevated plasma and urinary concentrations of green tea catechins associated with improved plasma lipid profile in healthy Japanese women.

    PubMed

    Takechi, Ryusuke; Alfonso, Helman; Hiramatsu, Naoko; Ishisaka, Akari; Tanaka, Akira; Tan, La'Belle; Lee, Andy H

    2016-03-01

    This study investigated green tea catechins in plasma and urine and chronic disease biomarkers. We hypothesized that plasma and urinary concentration of green tea catechins are associated with cardiovascular disease and diabetes biomarkers. First void urine and fasting plasma samples were collected from 57 generally healthy females aged 38 to 73 years (mean, 52 ± 8 years) recruited in Himeji, Japan. The concentrations of plasma and urinary green tea catechins were determined by liquid chromatography coupled with mass tandem spectrometer. Low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, triglyceride, glucose, insulin, glycated hemoglobin, and C-reactive protein in plasma/serum samples were analyzed by a commercial diagnostic laboratory. Statistical associations were assessed using Spearman correlation coefficients. The results showed weak associations between plasma total catechin and triglyceride (r = -0.30) and LDL cholesterol (r = -0.28), whereas plasma (-)-epigallocatechin-3-gallate, (-)-epigallocatechin, (-)-epicatechin-3-gallate, and (-)-epicatechin exhibited weak to moderate associations with triglyceride or LDL cholesterol, but little associations with HDL cholesterol, body fat, and body mass index were evident. Urinary total catechin was weakly associated with triglyceride (r = -0.19) and LDL cholesterol (r = -0.15), whereas urinary (-)-epigallocatechin-3-gallate (r = -0.33), (-)-epigallocatechin (r = -0.23), and (-)-epicatechin-3-gallate (r = -0.33) had weak to moderate correlations with triglyceride and similarly with body fat and body mass index. Both plasma (r = -0.24) and urinary (r = -0.24) total catechin, as well as individual catechins, were weakly associated with glycated hemoglobin. Plasma total and individual catechins were weakly to moderately associated with C-reactive protein, but not the case for urinary catechins. In conclusion, we found weak to moderate associations between plasma and urinary green tea catechin concentrations and plasma biomarkers of cardiovascular disease and diabetes. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. The current-density distribution in a pulsed dc magnetron deposition discharge

    NASA Astrophysics Data System (ADS)

    Vetushka, Alena; Bradley, James W.

    2007-04-01

    Using a carefully constructed magnetic probe (a B-dot probe) the spatial and temporal evolution of the perturbation in the magnetic field ΔB in an unbalanced pulsed dc magnetron has been determined. The plasma was run in argon at a pressure of 0.74 Pa and the plasma ions sputtered a pure graphite target. The pulse frequency and duty were set at 100 kHz and 55%, respectively. From the ΔB measurements (measured with magnitudes up to about 0.01 mT) the axial, azimuthal and radial components of the total current density j in the plasma bulk were determined. In the plasma 'on' phase, the axial current density jz has a maximum value of approximately 200 A m-2 above the racetrack region, while high values in the azimuthal current density jΦ are distributed in a region from 1 to 3 cm into the bulk plasma with jΦ exceeding 350 A m-2. In the 'off' phase of the plasma, jz decays almost instantaneously (at least within the 100 ns time-resolution of the ΔB measurements) as the electric field collapses; however, jΦ decays with a characteristic time constant of about 1 µs. This slow decay can be attributed to the presence of decaying Grad-B and curvature drifts, with their rates controlled by the decay in the plasma density. A comparison between axial and azimuthal current densities in the plasma 'on' time, when the plasma is being driven, strongly indicates that classical transport does not operate in the magnetron discharge.

  9. The effect of the isotope on the H-mode density limit

    NASA Astrophysics Data System (ADS)

    Huber, A.; Wiesen, S.; Bernert, M.; Brezinsek, S.; Chankin, A. V.; Sergienko, G.; Huber, V.; Abreu, P.; Boboc, A.; Brix, M.; Carralero, D.; Delabie, E.; Eich, T.; Esser, H. G.; Guillemaut, C.; Jachmich, S.; Joffrin, E.; Kallenbach, A.; Kruezi, U.; Lang, P.; Linsmeier, Ch.; Lowry, C. G.; Maggi, C. F.; Matthews, G. F.; Meigs, A. G.; Mertens, Ph.; Reimold, F.; Schweinzer, J.; Sips, G.; Stamp, M.; Viezzer, E.; Wischmeier, M.; Zohm, H.; contributors, JET; ASDEX Upgrade Team

    2017-08-01

    In order to understand the mechanisms for the H-mode density limit in machines with fully metallic walls, systematic investigations of H-mode density limit plasmas in experiments with deuterium and hydrogen external gas fuelling have been performed on JET-ILW. The observed H-mode density limit on JET in D- as well as in H-plasmas demonstrates similar operation phases: the stable H-mode phase, degrading H-mode, breakdown of the H-mode with energy confinement deterioration accompanied by a dithering cycling phase, followed by the L-mode phase. The density limit is not related to an inward collapse of the hot core plasma due to an overcooling of the plasma periphery by radiation. Indeed, independently of the isotopic effect, the total radiated power stay almost constant during the H-mode phase until the H-L back transition. It was observed in D- and H-plasmas that neither detachment, nor the X-point MARFE itself do trigger the H-L transition and that they thus do not present a limit on the plasma density. It is the plasma confinement, most likely determined by edge parameters, which is ultimately responsible for the H-mode DL. By comparing similar discharges but fuelled with either deuterium or hydrogen, we have found that the H-mode density limit exhibits a dependence on the isotope mass: the density limit is up to 35% lower in hydrogen compared to similar deuterium plasma conditions (the obtained density limit is in agreement with the Greenwald limit for D-plasma). In addition, the density limit is nearly independent of the applied power both in deuterium or hydrogen fuelling conditions. The measured Greenwald fractions are consistent with the predictions from a theoretical model based on an MHD instability theory in the near-SOL. The JET operational domains are significantly broadened when increasing the plasma effective mass (e.g. tritium or deuterium-tritium operation), i.e. the L to H power threshold is reduced whereas the density limit for the L-mode back transition is increased.

  10. Estimation of plasma lipids and its significance on histopathological grades in oral cancer: Prognostic significance an original research.

    PubMed

    Sherubin, Eugenia J; Kannan, Karthiga S; Kumar, Dhineksh N; Joseph, Isaac

    2013-01-01

    Alterations in the lipid profile have long been associated with various cancers because lipids play a key role in maintenance of cell integrity. This study was to estimate the plasma lipid levels in patients with oral cancer and to correlate the values with the histopathological grades. The study group included 50 patients with oral cancer aged between 20 and 60 years who had visited the Department of Oral Medicine and Radiology during the period of September 2005 to July 2007. After the histotopathological confirmation, their plasma lipid levels were estimated using auto analyzer and the data was statistically analyzed. The study revealed a significant decrease in the total plasma lipid levels in patients with oral cancer in comparison with the standard values. Comparing the plasma lipid levels with the histopathological grades, we observed a significant variation in the levels of total cholesterol, very low density lipoprotein, low-density lipoprotein, high-density lipoprotein and triglycerides. The variation in the levels of plasma cholesterol and other lipid constituents in patients with cancer might be due to their increased utilization by neoplastic cells for new membrane biosynthesis. This study was an attempt to estimate the plasma lipids in oral cancer patients and its significance on histopathological grades. We observed a relationship between lower plasma lipids and oral cancer. The result of our study strongly warrants an in-depth research with larger samples and a longer follow-up to consider the low plasma lipid status in oral cancer patients as a useful indicator to assess the course and prognosis of the disease.

  11. DE 1 observations of type 1 counterstreaming electrons and field-aligned currents

    NASA Technical Reports Server (NTRS)

    Lin, C. S.; Burch, J. L.; Barfield, J. N.; Sugiura, M.; Nielsen, E.

    1984-01-01

    Dynamics Explorer 1 satellite observations of plasma and magnetic fields during type one counterstreaming electron events are presented. Counterstreaming electrons are observed at high altitudes in the region of field-aligned current. The total current density computed from the plasma data in the 18-10,000 eV energy range is generally about 1-2 micro-A/sq m. For the downward current, low-energy electrons contribute more than 40 percent of the total plasma current density integrated above 18 eV. For the upward current, such electrons contribute less than 50 percent of that current density. Electron beams in the field-aligned direction are occasionally detected. The pitch angle distributions of counterstreaming electrons are generally enhanced at both small and large pitch angles. STARE simultaneous observations for one DE 1 pass indicated that the field-aligned current was closed through Pedersen currents in the ionosphere. The directions of the ionospheric current systems are consistent with the DE 1 observations at high altitudes.

  12. The isolation and subfractionation of plasma membrane from the cellular slime mould Dictyostelium discoideum

    PubMed Central

    Green, Anita A.; Newell, Peter C.

    1974-01-01

    A procedure for the isolation and separation of three different subfractions of plasma membrane from the cellular slime mould Dictyostelium discoideum is described. The cells were disrupted by freeze-thawing in liquid N2 and plasma membranes were purified by equilibrium centrifugation in a sucrose gradient. The cell surface was labelled with radioactive iodide by using the lactoperoxidase iodination method. Alkaline phosphatase was identified as a plasma-membrane marker by its co-distribution with [125I]iodide. 5′-Nucleotidase, which has been widely described as a plasma-membrane marker enzyme in mammalian tissues, was not localized to any marked extent in D. discoideum plasma membrane. The isolated plasma membranes showed a 24-fold enrichment of alkaline phosphatase specific activity relative to the homogenate and a yield of 50% of the total plasma membranes. Determination of succinate dehydrogenase and NADPH–cytochrome c reductase activities indicated that the preparation contained 2% of the total mitochondria and 3% of the endoplasmic reticulum. When the plasma-membrane preparation was further disrupted in a tight-fitting homogenizer, three plasma-membrane subfractions of different densities were obtained by isopycnic centrifugation. The enrichment of alkaline phosphatase was greatest in the subfraction with the lowest density. This fraction was enriched 36-fold relative to the homogenate and contained 19% of the total alkaline phosphatase activity but only 0.08% of the succinate dehydrogenase activity and 0.34% of the NADPH–cytochrome c reductase activity. Electron microscopy of this fraction showed it to consist of smooth membrane vesicles with no recognizable contaminants. ImagesPLATE 1 PMID:4156170

  13. Ion beams in multi-species plasmas

    NASA Astrophysics Data System (ADS)

    Aguirre, E. M.; Scime, E. E.; Good, T. N.

    2018-04-01

    Argon and xenon ion velocity distribution functions are measured in Ar-He, Ar-Xe, and Xe-He expanding helicon plasmas to determine if ion beam velocity is enhanced by the presence of lighter ions. Contrary to observations in mixed gas sheath experiments, we find that adding a lighter ion does not increase the ion beam speed. The predominant effect is a reduction of ion beam velocity consistent with increased drag arising from increased gas pressure under all conditions: constant total gas pressure, equal plasma densities of different ions, and very different plasma densities of different ions. These results suggest that the physics responsible for the acceleration of multiple ion species in simple sheaths is not responsible for the ion acceleration observed in expanding helicon plasmas.

  14. Plasma observations at the Earth's magnetic equator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Olsen, R.C.; Shawhan, S.D.; Gallagher, D.L.

    1987-03-01

    The magnetic equator provides a unique location for thermal plasma and plasma wave measurements. Plasma populations are found to be confined within a few degrees latitude of the equator, particularly the ions. The equatorially trapped ion population is found to be primarily hydrogen, and the authors find little evidence for preferential heating of heavier ions. Helium is occasionally found to be heated along with the protons, and forms about 10% of the equatorially trapped populations at such times, similar to the percentage of He{sup +} in the cold, core plasma of the plasmasphere. One case of a heated O{sup +}more » component was found; at the 0.1% level it generally comprises in the outer plasmasphere core plasma. The heated H{sup +} ions can be characterized by a bi-Maxwellian with kT{sub {parallel}} = 0.5-1.0 eV, and kT = 5-50 eV, with a density of 10-100 cm{sup {minus}3}. The total plasma density, as inferred from the plasma wave instrument measurements of the upper hybrid measurements of the upper hybrid resonance (UHR), is relatively constant with latitude, occasionally showing a local minimum at the magnetic equator, even though the ion flux has increased substantially. The first measurements of the equatorially trapped plasma and coincident UHR measurements show that the trapped plasma is a feature of the plasmapause region, found at total plasma densities of 20-200 cm{sup {minus}3}. The warm, trapped plasma is found in conjunction with equatorial noise, a plasma wave feature found at frequencies near 100 Hz, with a broad spectrum generally found between the proton gyrofrequency at the low frequency edge and the geometric mean gyrofrequency at the high frequency edge. This latter frequency is generally the lower hybrid resonance (LHR) for a proton-electron plasma. Sharp spatial boundaries are occasionally found with latitude, delimiting the equatorially trapped plasma.« less

  15. Density and beta limits in the Madison Symmetric Torus Reversed-Field Pinch

    NASA Astrophysics Data System (ADS)

    Caspary, Kyle Jonathan

    Operational limits and the underlying physics are explored on the Madison Symmetric Torus (MST) Reversed-Field Pinch (RFP) using deuterium pellet fueling. The injection of a fast pellet provides a large source of fuel in the plasma edge upon impact with the vessel wall, capable of triggering density limit terminations for the full range of plasma current, up to 600 kA. As the pellet size and plasma density increase, approaching the empirical Greenwald limit, plasma degradation is observed in the form of current decay, increased magnetic activity in the edge and core, increased radiation and plasma cooling. The complete termination of the plasma is consistent with the Greenwald limit; however, a slightly smaller maximum density is observed in discharges without toroidal field reversal. The plasma beta is the ratio of the plasma pressure to the confining magnetic pressure. Beta limits are known to constrain other magnetic confinement devices, but no beta limit has yet been established on the RFP. On MST, the highest beta values are obtained in improved confinement discharges with pellet fueling. By using pellet injection to scan the plasma density during PPCD, we also achieve a scan of Ohmic input power due to the increase in plasma resistivity. We observe a factor of 3 or more increase in Ohmic power as we increase the density from 1*1019 to 3*10 19 m-3. Despite this increased Ohmic power, the electron contribution to beta is constant, suggesting a confinement limited beta for the RFP. The electrons and ions are classically well coupled in these cold, dense pellet fueled plasmas, so the increase in total beta at higher density is primarily due to the increased ion contribution. The interaction of pellet fueling and NBI heating is explored. Modeling of MST's neutral heating beam suggests an optimal density for beam power deposition of 2-3*1019 m-3. Low current, NBI heated discharges show evidence of an increased electron beta in this density range. Additionally, the fast ion population can enhance ablation as well as cause pellet deflection. Other exploratory experiments with the pellet injection system explore additional injection scenarios and expand the injector capabilities.

  16. Kefir consumption does not alter plasma lipid levels or cholesterol fractional synthesis rates relative to milk in hyperlipidemic men: a randomized controlled trial [ISRCTN10820810

    PubMed Central

    St-Onge, Marie-Pierre; Farnworth, Edward R; Savard, Tony; Chabot, Denise; Mafu, Akier; Jones, Peter JH

    2002-01-01

    Background Fermented milk products have been shown to affect serum cholesterol concentrations in humans. Kefir, a fermented milk product, has been traditionally consumed for its potential health benefits but has to date not been studied for its hypocholesterolemic properties. Methods Thirteen healthy mildly hypercholesterolemic male subjects consumed a dairy supplement in randomized crossover trial for 2 periods of 4 wk each. Subjects were blinded to the dairy supplement consumed. Blood samples were collected at baseline and after 4 wk of supplementation for measurement of plasma total, low-density lipoprotein, and high-density lipoprotein cholesterol and triglyceride concentrations, as well as fatty acid profile and cholesterol synthesis rate. Fecal samples were collected at baseline and after 2 and 4 wk of supplementation for determination of fecal short chain fatty acid level and bacterial content. Results Kefir had no effect on total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglyceride concentrations nor on cholesterol fractional synthesis rates after 4 wk of supplementation. No significant change on plasma fatty acid levels was observed with diet. However, both kefir and milk increased (p < 0.05) fecal isobutyric, isovaleric and propionic acids as well as the total amount of fecal short chain fatty acids. Kefir supplementation resulted in increased fecal bacterial content in the majority of the subjects. Conclusions Since kefir consumption did not result in lowered plasma lipid concentrations, the results of this study do not support consumption of kefir as a cholesterol-lowering agent. PMID:11825344

  17. Feasibility of Juno radio occultations of the Io plasma torus

    NASA Astrophysics Data System (ADS)

    Phipps, P. H.; Withers, P.

    2016-12-01

    Jupiter's magnetosphere is driven by internally produced plasma. The innermost Galilean satellite, Io, isthe dominant source of this plasma. Volcanoes on Io's surface create an atmosphere of sulfur and oxygenwhich escapes into Jupiter's magnetosphere and becomes ionized. This ionized material is trapped byJupiter's magnetic field and creates a torus of plasma centered at Io's orbital radius, called the Io plasmatorus. This torus is divided into three regions distinct in both density and composition. Densities in thistorus can be probed by spacecraft via radio occultations. A radio occultation occurs when plasma comesbetween a spacecraft and a receiver during a time when the spacecraft is sending a radio signal. The Junospacecraft, which arrived in orbit around Jupiter in July 2016, is in an orbit which will be ideal forperforming radio occultations of the Io plasma torus. We test the feasibility of using thetelecommunications system on the Juno spacecraft to perform a radio occultation. Io plasma torusdensities derived from Voyager 1 data are used in creating a model torus. Using the Ka and X-band radiofrequencies we derive vertical profiles for the total electron content of the modeled Io plasma torus. AMarkov Chain Monte Carlo fit is performed on the derived profiles to extract, for each of the torusregions, the scale height and peak total electron content. The scale height can be used to derive atemperature for the torus while the peak total electron content can be used to derive the peak electrondensity. We show that Juno radio occultation measurements of the Io plasma torus are feasible andscientifically valuable.

  18. Experimental study of plasma properties in the shadow of the T--10 mushroom limiter

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Alferov, A.A.; Vershkov, V.A.; Grashin, S.A.

    1988-04-01

    The plasma properties in the shadow of a mushroom-shaped limiter installed in a lower port of the tokamak have been studied. A study of the asymmetry of the plasma streams on the ion and electron sides of the limiter leads to the conclusion that there are two mechanisms for the occurrence of the asymmetry: the toroidal rotation of the plasma and a predominant escape of plasma to the wall through the outer part of the torus. The asymmetry observed in the plasma floating potentials near the limiter leads to the flow of a current close to the Spitzer value j/submore » S/ through the limiter. With increasing plasma density, the plasma density in the channels of the limiter increases, and the temperature of this plasma decreases, so the loss of charged particles to the limiter depends only weakly on the average density. This circumstance is related to the degradation of the plasma confinement with decreasing density. The total flux of charged particles to the limiter is comparable to the flux of these particles out of the plasma column. The plasma stream into the channels is approximately ambipolar, and the power levels drawn by the neutralization plate are on the order of 10j/sub S/T/sub e//e. The behavior of the neutral gas pressure in the volume near the limiter as a function of the plasma streams into the channels is nonlinear. The maximum pressure is 3x10/sup -2/ torr.« less

  19. Numerical studies on alpha production from high energy proton beam interaction with Boron

    NASA Astrophysics Data System (ADS)

    Moustaizis, S. D.; Lalousis, P.; Hora, H.; Korn, G.

    2017-05-01

    Numerical investigations on high energy proton beam interaction with high density Boron plasma allows to simulate conditions concerning the alpha production from recent experimental measurements . The experiments measure the alpha production due to p11B nuclear fusion reactions when a laser-driven high energy proton beam interacts with Boron plasma produced by laser beam interaction with solid Boron. The alpha production and consequently the efficiency of the process depends on the initial proton beam energy, proton beam density, the Boron plasma density and temperature, and their temporal evolution. The main advantage for the p11B nuclear fusion reaction is the production of three alphas with total energy of 8.9 MeV, which could enhance the alpha heating effect and improve the alpha production. This particular effect is termed in the international literature as the alpha avalanche effect. Numerical results using a multi-fluid, global particle and energy balance, code shows the alpha production efficiency as a function of the initial energy of the proton beam, the Boron plasma density, the initial Boron plasma temperature and the temporal evolution of the plasma parameters. The simulations enable us to determine the interaction conditions (proton beam - B plasma) for which the alpha heating effect becomes important.

  20. Diagnostics and results from coaxial plasma gun development for the PLX- α project

    NASA Astrophysics Data System (ADS)

    Case, A.; Brockington, S.; Cruz, E.; Witherspoon, F. D.

    2016-10-01

    We present results from the diagnostics used during development of the contoured gap coaxial plasma guns for the PLX- α project at LANL. Plasma-jet diagnostics include fast photodiodes for velocimetry, a ballistic pendulum for total plasmoid momentum, and interferometry for line integrated density. Deflectometry will be used for line integrated perpendicular density gradients. Time-resolved high-resolution spectroscopy using a novel detector and time-integrated survey spectroscopy are used for measurements of velocity and temperature, as well as impurities. We will also use a Faraday cup for density, fast imaging for plume geometry, and time-integrated imaging for overall light emission. Experimental results are compared to the desired target parameters for the plasma jets (up to n 2 ×1016cm-3 , v 50km / s , mass 5gm , radius = 4cm , and length 10cm). This work supported by the ARPA-E ALPHA Program.

  1. LASER APPLICATIONS AND OTHER TOPICS IN QUANTUM ELECTRONICS: Reflection of an electromagnetic pulse from a subcritical waveguide taper and from a supercritical-density plasma in a waveguide

    NASA Astrophysics Data System (ADS)

    Rukhadze, Anri A.; Tarakanov, V. P.

    2006-09-01

    Two related problems are studied by numerical simulations using the KARAT code: the reflection of the TM01 mode of an electromagnetic pulse from the subcritical taper of the section of a circular waveguide and the reflection of the same pulse from a 'cold' collisionless plasma with a density increasing up to a supercritical value along the waveguide axis. It is shown that in the former case the pulse is totally reflected with an insignificant distortion of its shape, in accordance with the linear theory. In the latter case, the character of reflection depends substantially on the plasma density increase length, the pulse duration, and the wave field amplitude, a significant field deceleration and amplitude growth occurring near the critical point; the pulse absorption in the plasma far exceeds the absorption due to the linear transformation of the incident transverse wave to the longitudinal plasma oscillations.

  2. Effects of climatic factors on plasma lipid levels: A 5-year longitudinal study in a large Chinese population.

    PubMed

    Zhou, Xiaoming; Lin, Haiyan; Zhang, Shigang; Ren, Jianwei; Wang, Zhe; Zhang, Yun; Wang, Mansen; Zhang, Qunye

    2016-01-01

    The rules and mechanisms of seasonal changes in plasma lipid levels, which may be related to annual rhythmicity of incidence and mortality of cardiovascular diseases, are still controversial. The objectives of this study were to study the effects of climatic factors on plasma lipid levels and to preliminarily reveal mechanisms of annual rhythmicity of plasma lipid levels. A longitudinal study was performed using health examination data of 5 consecutive years (47,270 subjects) in Jinan, China. The climate in Jinan is typical temperate continental monsoon climate with huge temperature difference between winter and summer (>30°C). After considering and adjusting those classical lipid-associated risk factors, such as age, gender, diet, exercise, blood pressure, body weight, change of body weight, body mass index, glycemia, alanine aminotransferase, and creatinine, only air temperature could still significantly affect plasma lipid levels among the main climatic factors (humidity, precipitation, and so forth). For men, total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol was decreased significantly 0.35, 0.18, and 0.06 mmol/L, respectively, whereas triglyceride was increased significantly 0.12 mmol/L for every 10°C increase in air temperature. For women, total cholesterol and high-density lipoprotein cholesterol were decreased notably 0.73 and 0.32 mmol/L, and low-density lipoprotein cholesterol was increased significantly 0.26 mmol/L for every 10°C increase in air temperature, whereas triglyceride was not significantly affected by air temperature. Air temperature is an independent risk factor for plasma lipid levels besides those classical lipid-associated risk factors. The annual air temperature fluctuations might be an important mechanism of the seasonal changes of lipids. Copyright © 2016 National Lipid Association. Published by Elsevier Inc. All rights reserved.

  3. The collisional drift mode in a partially ionized plasma. [in the F region

    NASA Technical Reports Server (NTRS)

    Hudson, M. K.; Kennel, C. F.

    1974-01-01

    The structure of the drift instability was examined in several density regimes. Let sub e be the total electron mean free path, k sub z the wave-vector component along the magnetic field, and the ratio of perpendicular ion diffusion to parallel electron streaming rates. At low densities (k sub z lambda 1) the drift mode is isothermal and should be treated kineticly. In the finite heat conduction regime square root of m/M k sub z Lambda sub 1) the drift instability threshold is reduced at low densities and increased at high densities as compared to the isothermal threshold. Finally, in the energy transfer limit (k sub z kambda sub e square root of m/M) the drift instability behaves adiabatically in a fully ionized plasma and isothermally in a partially ionized plasma for an ion-neutral to Coulomb collision frequency ratio.

  4. Variations of ionospheric plasma at different altitudes before the 2005 Sumatra Indonesia Ms 7.2 earthquake

    NASA Astrophysics Data System (ADS)

    Liu, Jing; Zhang, Xuemin; Novikov, Victor; Shen, Xuhui

    2016-09-01

    In recent years, many researchers pay more attention to abnormities before earthquake, and in this study, seismo-ionospheric synchronous disturbances at different altitudes by GPS and satellite observations were first studied around one Sumatra Indonesia Ms 7.2 earthquake that occurred on 5 July 2005. By using the same temporal and spatial methods, data of GPS-total electron content (TEC) from Jet Propulsion Laboratory, electron density (Ne) from Detection of Electro-Magnetic Emissions Transmitted from Earthquake Regions, and ion density (Ni) from Defense Meteorological Satellite Program were deeply analyzed. The ionospheric plasma disturbances in GPS-TEC and increasement of Ne at 710 km were found on 4 July, and plasma density at the three altitudes has all increased on 7 July after the earthquake. All the disturbances were not just above the epicenter. TEC perturbations have happened at the east of the epicenter for the two days, and electron density enhancement at 710 km has moved to west of the TEC perturbations at the same time on 4 July, which may be caused by E × B drift. The moving direction of upgoing plasma was simulated using SAMI2 model. The results have shown that the plasma will move to higher altitude along the geomagnetic force line, which could exactly account for the plasma density enhancement in the northern direction of the geomagnetic south latitude earthquake.

  5. Generalized charge-screening in relativistic Thomas–Fermi model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Akbari-Moghanjoughi, M.

    In this paper, we study the charge shielding within the relativistic Thomas-Fermi model for a wide range of electron number-densities and the atomic-number of screened ions. A generalized energy-density relation is obtained using the force-balance equation and taking into account the Chandrasekhar's relativistic electron degeneracy pressure. By numerically solving a second-order nonlinear differential equation, the Thomas-Fermi screening length is investigated, and the results are compared for three distinct regimes of the solid-density, warm-dense-matter, and white-dwarfs (WDs). It is revealed that our nonlinear screening theory is compatible with the exponentially decaying Thomas-Fermi-type shielding predicted by the linear response theory. Moreover, themore » variation of relative Thomas-Fermi screening length shows that extremely dense quantum electron fluids are relatively poor charge shielders. Calculation of the total number of screening electrons around a nucleus shows that there is a position of maximum number of screening localized electrons around the screened nucleus, which moves closer to the point-like nucleus by increase in the plasma number density but is unaffected due to increase in the atomic-number value. It is discovered that the total number of screening electrons, (N{sub s}∝r{sub TF}{sup 3}/r{sub d}{sup 3} where r{sub TF} and r{sub d} are the Thomas-Fermi and interparticle distance, respectively) has a distinct limit for extremely dense plasmas such as WD-cores and neutron star crusts, which is unique for all given values of the atomic-number. This is equal to saying that in an ultrarelativistic degeneracy limit of electron-ion plasma, the screening length couples with the system dimensionality and the plasma becomes spherically self-similar. Current analysis can provide useful information on the effects of relativistic correction to the charge screening for a wide range of plasma density, such as the inertial-confined plasmas and compact stellar objects.« less

  6. Examination of the relation between periodontal health status and cardiovascular risk factors: serum total and high density lipoprotein cholesterol, C-reactive protein, and plasma fibrinogen.

    PubMed

    Wu, T; Trevisan, M; Genco, R J; Falkner, K L; Dorn, J P; Sempos, C T

    2000-02-01

    Using data from the Third National Health and Nutrition Examination Survey (1988-1994), the authors examined the relation between periodontal health and cardiovascular risk factors: serum total and high density lipoprotein cholesterol, C-reactive protein, and plasma fibrinogen. A total of 10,146 participants were included in the analyses of cholesterol and C-reactive protein and 4,461 in the analyses of fibrinogen. Periodontal health indicators included the gingival bleeding index, calculus index, and periodontal disease status (defined by pocket depth and attachment loss). While cholesterol and fibrinogen were analyzed as continuous variables, C-reactive protein was dichotomized into two levels. The results show a significant relation between indicators of poor periodontal status and increased C-reactive protein and fibrinogen. The association between periodontal status and total cholesterol level is much weaker. No consistent association between periodontal status and high density lipoprotein cholesterol was detectable. Similar patterns of association were observed for participants aged 17-54 years and those 55 years and older. In conclusion, this study suggests that total cholesterol, C-reactive protein, and fibrinogen are possible intermediate factors that may link periodontal disease to elevated cardiovascular risk.

  7. Free-bound electron exchange contribution to l-split atomic structure in dense plasmas

    NASA Astrophysics Data System (ADS)

    Bennadji, K.; Rosmej, F.; Lisitsa, V. S.

    2013-11-01

    An analytical expression for the exchange energy between the bound electron in hydrogen-like ions and the free electrons of plasma is proposed. Two limiting cases are identified: 1) the low temperature limit where the energy depends linearly on density and on the ion charge as 1/Z2 but does not depend on the temperature itself, 2) the high temperature limit where the energy depends on temperature as 1/T but does not depend on the ion charge. These two regimes are separated by a characteristic temperature (T∗ = 4Z2Ry) which is a universal parameter depending only on the charge Z of the ions. We presented numerical results for aluminum: the exchange energy contributes about 15% to the total plasma energy and can reach an order of 10-4 of the total transition energy. Comparison to the Local-density Approximation (Kohn-Sham) exchange energy shows a good agreement.

  8. One-dimensional Ar-SF{sub 6} hydromodel at low-pressure in e-beam generated plasmas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Petrov, George M., E-mail: george.petrov@nrl.navy.mil; Boris, David R.; Petrova, Tzvetelina B.

    2016-03-15

    A one-dimensional steady-state hydrodynamic model of electron beam generated plasmas produced in Ar-SF{sub 6} mixtures at low pressure in a constant magnetic field was developed. Simulations were performed for a range of SF{sub 6} partial pressures at constant 30 mTorr total gas pressure to determine the spatial distribution of species densities and fluxes. With the addition of small amount of SF{sub 6} (∼1%), the confining electrostatic field sharply decreases with respect to the pure argon case. This effect is due to the applied magnetic field inhibiting electron diffusion. The hallmark of electronegative discharge plasmas, positive ion—negative ion core and positivemore » ion—electron edge, was not observed. Instead, a plasma with large electronegativity (∼100) is formed throughout the volume, and only a small fraction (≈30%) of the parent SF{sub 6} molecules were dissociated to F{sub 2}, SF{sub 2}, and SF{sub 4}. Importantly, F radical densities were found to be very low, on the order of the ion density. Model predictions for the electron density, ion density, and plasma electronegativity are in good agreement with experimental data over the entire range of SF{sub 6} concentrations investigated.« less

  9. Plasma concentrations of lipids and lipoproteins in newborn kids and female Baladi goats during late pregnancy and onset of lactation.

    PubMed

    Hussein, S A; Azab, M E

    1998-01-01

    Concentrations of blood lipids and some lipoproteins were investigated in normal female Baladi goats during late pregnancy, parturition and onset of lactation as well as in their newborn kids during the first two weeks of life. A total number of 60 herparinized blood samples was collected from does at 4, 3, 2 and 1 weeks pre-partum, day of parturition and at 1, 2, 3 and 4 weeks postpartum. In addition, blood samples were also collected from their newborn kids during the first two weeks of life (day of birth, 1 and 2 weeks of age). Plasma was separated and analyzed for concentration of total lipid, total cholesterol, triacylglycerols, phospholipids, non esterified fatty acids (NEFA) and some lipoproteins as high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C). The obtained results revealed that there was a significant decrease in plasma level of total lipids at one week after parturition. Plasma level of triaclyglycerols was significantly higher at 4, 3 and 2 weeks before parturition. This increase became very highly significant at one week before parturition. Meanwhile, plasma phospholipid concentrations showed a significant decrease at 3 weeks before parturition, followed by an significant increase at 2 and 3 weeks after parturition and highly significant increase at 4 weeks after parturition. The concentration of plasma NEFA showed a significant increase at 4 weeks before parturition followed by a very highly significant increase at 2 and 1 week before parturition. On the other hand plasma NEFA was non detected at 2, 3 and 4 weeks post-partum when compared with the value reported at day of parturition. Regarding plasma lipoprotein concentrations the obtained results showed that there was a significant increase in plasma HDL-C level at 2 and 3 weeks after parturition, followed by a very highly significant decrease at the fourth week post-partum. However, plasma LDL-C level showed a significant decrease at 3, 2 and 1 weeks before parturition, followed by a further highly significant decrease at 1 and 2 weeks post-partum. In newborn kids plasma concentrations of total lipids, total cholesterol, phospholipids, HDL-C and LDL-C were very markedly increased at 1 and 2 weeks of age. However, plasma triacylglycerol concentrations showed a highly significant decrease at 1 and 2 weeks of age. The concentration of plasma NEFA showed a very highly significant decrease at 2 weeks of age, whereas, at one week of age plasma NEFA were not detected in comparison with first day of life.

  10. Development of internal magnetic probe for current density profile measurement in Versatile Experiment Spherical Torus

    NASA Astrophysics Data System (ADS)

    Yang, J.; Lee, J. W.; Jung, B. K.; Chung, K. J.; Hwang, Y. S.

    2014-11-01

    An internal magnetic probe using Hall sensors to measure a current density profile directly with perturbation of less than 10% to the plasma current is successfully operated for the first time in Versatile Experiment Spherical Torus (VEST). An appropriate Hall sensor is chosen to produce sufficient signals for VEST magnetic field while maintaining the small size of 10 mm in outer diameter. Temperature around the Hall sensor in a typical VEST plasma is regulated by blown air of 2 bars. First measurement of 60 kA VEST ohmic discharge shows a reasonable agreement with the total plasma current measured by Rogowski coil in VEST.

  11. Affinity proteomic profiling of plasma for proteins associated to area-based mammographic breast density.

    PubMed

    Byström, Sanna; Eklund, Martin; Hong, Mun-Gwan; Fredolini, Claudia; Eriksson, Mikael; Czene, Kamila; Hall, Per; Schwenk, Jochen M; Gabrielson, Marike

    2018-02-14

    Mammographic breast density is one of the strongest risk factors for breast cancer, but molecular understanding of how breast density relates to cancer risk is less complete. Studies of proteins in blood plasma, possibly associated with mammographic density, are well-suited as these allow large-scale analyses and might shed light on the association between breast cancer and breast density. Plasma samples from 1329 women in the Swedish KARMA project, without prior history of breast cancer, were profiled with antibody suspension bead array (SBA) assays. Two sample sets comprising 729 and 600 women were screened by two different SBAs targeting a total number of 357 proteins. Protein targets were selected through searching the literature, for either being related to breast cancer or for being linked to the extracellular matrix. Association between proteins and absolute area-based breast density (AD) was assessed by quantile regression, adjusting for age and body mass index (BMI). Plasma profiling revealed linear association between 20 proteins and AD, concordant in the two sets of samples (p < 0.05). Plasma levels of seven proteins were positively associated and 13 proteins negatively associated with AD. For eleven of these proteins evidence for gene expression in breast tissue existed. Among these, ABCC11, TNFRSF10D, F11R and ERRF were positively associated with AD, and SHC1, CFLAR, ACOX2, ITGB6, RASSF1, FANCD2 and IRX5 were negatively associated with AD. Screening proteins in plasma indicates associations between breast density and processes of tissue homeostasis, DNA repair, cancer development and/or progression in breast cancer. Further validation and follow-up studies of the shortlisted protein candidates in independent cohorts will be needed to infer their role in breast density and its progression in premenopausal and postmenopausal women.

  12. Increased plasma FGF21 level as an early biomarker for insulin resistance and metabolic disturbance in obese insulin-resistant rats.

    PubMed

    Tanajak, Pongpan; Pongkan, Wanpitak; Chattipakorn, Siriporn C; Chattipakorn, Nipon

    2018-05-01

    Propose: To investigate the temporal relationship between plasma fibroblast growth factor 21 levels, insulin resistance, metabolic dysfunction and cardiac fibroblast growth factor 21 resistance in long-term high-fat diet-induced obese rats. In total, 36 male Wistar rats were fed with either a normal diet or high-fat diet for 12 weeks. Blood was collected from the tail tip, and plasma was used to determine metabolic profiles and fibroblast growth factor 21 levels. Rats were sacrificed at weeks 4, 8 and 12, and the hearts were rapidly removed for the determination of cardiac fibroblast growth factor 21 signalling pathways. Body weight and plasma fibroblast growth factor 21 levels were increased after 4 weeks of consumption of a high-fat diet. At weeks 8 and 12, high-fat diet rats had significantly increased body weight and plasma fibroblast growth factor 21 levels, together with increased plasma insulin, HOMA index, area under the curve of glucose, plasma total cholesterol, plasma low-density lipoprotein cholesterol, serum malondialdehyde and cardiac malondialdehyde levels. However, plasma high-density lipoprotein cholesterol levels and cardiac fibroblast growth factor 21 signalling proteins (p-FGFR1 Tyr 154 , p-ERK1/2 Thr 202 /Tyr 204 and p-Akt Ser 473 ) were decreased, compared with normal diet rats. These findings suggest that plasma fibroblast growth factor 21 levels could be an early predictive biomarker prior to the development of insulin resistance, metabolic disturbance and cardiac fibroblast growth factor 21 resistance.

  13. Plasma visfatin level in lean women with PCOS: relation to proinflammatory markers and insulin resistance.

    PubMed

    Gen, Ramazan; Akbay, Esen; Muslu, Necati; Sezer, Kerem; Cayan, Filiz

    2009-04-01

    The present study was undertaken to investigate the association between plasma visfatin concentrations and inflammatory markers such as interleukin-6 (IL-6) and high-sensitive C-reactive protein (hsCRP) in company with several metabolic parameters in lean women with polycystic ovary syndrome (PCOS). The study group consisted of 21 lean women with PCOS (BMI 20.74 +/- 1.74 kg/m(2)) and 15 healthy, normally menstruating women (BMI 20.85 +/- 2.08 kg/m(2) control group). PCOS was defined according to the Rotterdam criteria. Visfatin, IL-6, hsCRP, hyperandrogenism markers and metabolic markers were examined in all PCOS and control women. Plasma visfatin level in the PCOS group was higher than that in the control group. Plasma hsCRP and IL-6 levels in PCOS group were similar with the control group. Plasma visfatin levels were positively associated with total cholesterol, high density lipoprotein, hirsutism score, total testosterone and FAI. Plasma visfatin level was negatively associated with SHBG. However, there were no correlation between plasma visfatin level and IL-6 and hsCRP. In multivariate regression analyses, only FAI and high density lipoprotein-cholesterol (HDL-C) showed a significant association with serum visfatin. Our data indicates that plasma visfatin levels are associated with HDL-C and markers of hyperandrogenism, but it is not associated with proinflammatory markers and insulin resistance in lean women with PCOS.

  14. Molybdenum electron impact width parameter measurement by laser-induced breakdown spectroscopy

    NASA Astrophysics Data System (ADS)

    Sternberg, E. M. A.; Rodrigues, N. A. S.; Amorim, J.

    2016-01-01

    In this work, we suggest a method for electron impact width parameter calculation based on Stark broadening of emission lines of a laser-ablated plasma plume. First, electron density and temperature must be evaluated by means of the Saha-Boltzmann plot method for neutral and ionized species of the plasma. The method was applied for laser-ablated molybdenum plasma plume. For molybdenum plasma electron temperature, which varies around 10,000 K, and electron density, which reaches values around 1018 cm-3, and considering that total measured line broadening was due experimental and Stark broadening mainly, electron impact width parameter of molybdenum emission lines was determined as (0.01 ± 0.02) nm. Intending to validate the presented method, it was analyzed the laser-ablated aluminum plasma plume and the obtained results were in agreement with the predicted on the literature.

  15. Regional body fat distribution and metabolic profile in postmenopausal women.

    PubMed

    Piché, Marie-Eve; Lapointe, Annie; Weisnagel, S John; Corneau, Louise; Nadeau, André; Bergeron, Jean; Lemieux, Simone

    2008-08-01

    The aim of the study was to examine how body fat distribution variables were associated with metabolic parameters in a sample of 113 postmenopausal women not receiving hormone therapy (56.9 +/- 4.4 years, 28.4 +/- 5.1 kg/m(2)). Body fat distribution variables (visceral adipose tissue [AT], subcutaneous AT, and total midthigh AT) were measured using computed tomography; body fat mass was assessed by hydrostatic weighing; insulin sensitivity was determined with the euglycemic-hyperinsulinemic clamp; fasting plasma glucose (FPG) and 2-hour plasma glucose (2hPG) concentrations were measured by a 75-g oral glucose load; and (high-sensitivity) C-reactive protein (hs-CRP) was measured using a highly sensitive assay. After controlling for fat mass, visceral AT was positively associated with plasma triglyceride, hs-CRP, FPG, and 2hPG, and negatively associated with high-density lipoprotein cholesterol (HDL-C) and insulin sensitivity. Total midthigh AT was negatively associated with apolipoprotein B, FPG, and 2hPG, and positively associated with insulin sensitivity. Stepwise multiple regression analyses including abdominal visceral AT, subcutaneous AT and total midthigh AT as independent variables showed that abdominal visceral AT best predicted the variance in plasma triglyceride, HDL-C, low-density lipoprotein peak particle size, hs-CRP, FPG, 2hPG, and insulin sensitivity. Abdominal subcutaneous AT was a significant predictor of only insulin sensitivity, whereas total midthigh AT predicted HDL-C, low-density lipoprotein peak particle size, and apolipoprotein B. These multivariate analyses also indicated that total midthigh AT was favorably related to these outcomes, whereas abdominal visceral AT and subcutaneous AT were unfavorably related. These results confirmed that abdominal visceral fat is a critical correlate of metabolic parameters in postmenopausal women. In addition, a higher proportion of AT located in the total midthigh depot is associated with a favorable metabolic profile.

  16. Radiated Power and Impurity Concentrations in the EXTRAP-T2R Reversed-Field Pinch

    NASA Astrophysics Data System (ADS)

    Corre, Y.; Rachlew, E.; Cecconello, M.; Gravestijn, R. M.; Hedqvist, A.; Pégourié, B.; Schunke, B.; Stancalie, V.

    2005-01-01

    A numerical and experimental study of the impurity concentration and radiation in the EXTRAP-T2R device is reported. The experimental setup consists of an 8-chord bolometer system providing the plasma radiated power and a vacuum-ultraviolet spectrometer providing information on the plasma impurity content. The plasma emissivity profile as measured by the bolometric system is peaked in the plasma centre. A one dimensional Onion Skin Collisional-Radiative model (OSCR) has been developed to compute the density and radiation distributions of the main impurities. The observed centrally peaked emissivity profile can be reproduced by OSCR simulations only if finite particle confinement time and charge-exchange processes between plasma impurities and neutral hydrogen are taken into account. The neutral hydrogen density profile is computed with a recycling code. Simulations show that recycling on metal first wall such as in EXTRAP-T2R (stainless steel vacuum vessel and molybdenum limiters) is compatible with a rather high neutral hydrogen density in the plasma centre. Assuming an impurity concentration of 10% for oxygen and 3% for carbon compared with the electron density, the OSCR calculation including lines and continuum emission reproduces about 60% of the total radiated power with a similarly centrally peaked emissivity profile. The centrally peaked emissivity profile is due to low ionisation stages and strongly radiating species in the plasma core, mainly O4+ (Be-like) and C3+ Li-like.

  17. Multiple Magnetic Storm Study of the High-Altitude Redistribution of Equatorial Plasma

    NASA Astrophysics Data System (ADS)

    Bust, G. S.; Crowley, G.; Curtis, N.; Anderson, D.

    2008-12-01

    During geomagnetic storms, particularly when prompt penetration electric fields (PPE) occur, the equatorial plasma can be lifted to very high altitudes and then diffuse along magnetic field lines to higher than normal latitudes. During these cases very high plasma density (total electron content (TEC) greater than 200 TECU) can be found at these higher latitudes. Shortly after the PPE lifts the equatorial plasma to higher altitudes, at least in the US sector, phenomena known as storm-enhanced density (SED) can occur. SEDs occur in the post-noon time frame and consist of a very high density bulge that seems to occur in the southern USA and Caribbean region, followed by a narrow plume of high density plasma that flows into the high-latitude throat near local noon, and across the polar cap. An outstanding research question is: Exactly how is the high density SED plasma, particularly in the bulge related to the PPE and lifting of the equatorial plasma? Ionospheric imaging of electron density and TEC seem to show a gap in density between the poleward extent of the equatorial plasma and the equatorial extent of the SED plasma. Further, there are magnetic storm events where SEDs do not form (November 2004 as a good example). This paper will investigate the relationship between the equatorial high altitude plasma distribution during magnetic storms, and the initiation and evolution of the SED feature. We will examine eight separate storms from 2003-2006 using the ionospheric data assimilation algorithm IDA4D. In particular we will focus on time periods when LEO satellite GPS TEC data is available from CHAMP, SACC, GRACE and the COSMIC constellation (2006 and beyond). These data sets directly measure the TEC above the satellites, and therefore are good tracers of the high altitude plasma distribution. IDA4D ingests these data sets and uses them to get an improved image of the plasma density for the topside ionosphere and plasmasphere. The resulting 4D images of high altitude densities will be cross compared for the various storms and the similarities and differences will be studied and correlated with various geophysical parameters such as the interplanetary magnetic field (Bz), Dst, hemispheric power, cross cap potential, PPE, equatorial vertical drifts, and the interplanetary electric field. The overall objective is to elucidate the physical relationships that govern the redistribution of equatorial plasma during storms, and the generation and evolution of SEDs.

  18. Seismo-ionospheric anomalies in ionospheric TEC and plasma density before the 17 July 2006 M7.7 south of Java earthquake

    NASA Astrophysics Data System (ADS)

    Tao, Dan; Cao, Jinbin; Battiston, Roberto; Li, Liuyuan; Ma, Yuduan; Liu, Wenlong; Zhima, Zeren; Wang, Lanwei; Wray Dunlop, Malcolm

    2017-04-01

    In this paper, we report significant evidence for preseismic ionospheric anomalies in total electron content (TEC) of the global ionosphere map (GIM) and plasma density appearing on day 2 before the 17 July 2006 M7.7 south of Java earthquake. After distinguishing other anomalies related to the geomagnetic activities, we found a temporal precursor around the epicenter on day 2 before the earthquake (15 July 2006), which agrees well with the spatial variations in latitude-longitude-time (LLT) maps. Meanwhile, the sequences of latitude-time-TEC (LTT) plots reveal that the TECs on epicenter side anomalously decrease and lead to an anomalous asymmetric structure with respect to the magnetic equator in the daytime from day 2 before the earthquake. This anomalous asymmetric structure disappears after the earthquake. To further confirm these anomalies, we studied the plasma data from DEMETER satellite in the earthquake preparation zone (2046.4 km in radius) during the period from day 45 before to day 10 after the earthquake, and also found that the densities of both electron and total ion in the daytime significantly increase on day 2 before the earthquake. Very interestingly, O+ density increases significantly and H+ density decreases, while He+ remains relatively stable. These results indicate that there exists a distinct preseismic signal (preseismic ionospheric anomaly) over the epicenter.

  19. Small, qualitative changes in fatty acid intake decrease plasma low-density lipoprotein-cholesterol levels in mildly hypercholesterolemic outpatients on their usual high-fat diets.

    PubMed

    Lecerf, Jean-Michel; Luc, Gérald; Marécaux, Nadine; Bal, Sylvie; Bonte, Jean-Paul; Lacroix, Brigitte; Cayzeele, Amélie

    2009-01-01

    The diet is the first step in managing hypercholesterolemia. The objective of the present study is to assess whether moderate changes in dietary fatty acids improve plasma lipid parameters in mildly hypercholesterolemic outpatients. Using a randomized double-blind study, 121 outpatients within two groups received an isocaloric amount of unsaturated margarine or butter. Clinical and anthropometric measurements and a 3-day food record were made. Chi-square and Fisher's tests were used to compare qualitative variables and the general linear procedure was used to compare the groups. Additional analyses were performed after adjustment. There was a significant difference (P <0.03) in low-density lipoprotein-cholesterol levels between the groups. Total cholesterol, low-density lipoprotein-cholesterol, non-high-density lipoprotein-cholesterol and apolipoprotein B values decreased in the unsaturated group in comparison with the saturated group. Low-density lipoprotein-cholesterol changes were correlated with the variation in polyunsaturated fatty acid intake and with plasma phospholipid linoleic acid levels. A small change in saturated by polyunsaturated fatty acid intake may improve plasma lipid parameters in mildly hypercholesterolemic subjects.

  20. Spatial Structure of Large-Scale Plasma Density Perturbations HF-Induced in the Ionospheric F 2 Region

    NASA Astrophysics Data System (ADS)

    Frolov, V. L.; Komrakov, G. P.; Glukhov, Ya. V.; Andreeva, E. S.; Kunitsyn, V. E.; Kurbatov, G. A.

    2016-07-01

    We consider the experimental results obtained by studying the large-scale structure of the HF-disturbed ionospheric region. The experiments were performed using the SURA heating facility. The disturbed ionospheric region was sounded by signals radiated by GPS navigation satellite beacons as well as by signals of low-orbit satellites (radio tomography). The results of the experiments show that large-scale plasma density perturbations induced at altitudes higher than the F2 layer maximum can contribute significantly to the measured variations of the total electron density and can, with a certain arrangement of the reception points, be measured by the GPS sounding method.

  1. Development of a low pressure microwave excited plasma and its application to the formation of microcrystalline silicon films

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kikukawa, Daisuke; Hori, Masaru; Honma, Koichiro

    2006-11-15

    Microwave excited plasma source operating at a low pressure of 1.5 Pa was newly developed. This plasma source was successfully applied to the formation of hydrogenated microcrystalline silicon films in a glass substrate with a mixture gas of silane (SiH{sub 4}), hydrogen (H{sub 2}), and xenon (Xe). It was found that the crystallinity of films was dramatically improved with decreasing pressure. The crystalline fraction was evaluated to be 82% at a substrate temperature of 400 deg. C, a mixture gas of SiH{sub 4}/H{sub 2}/Xe: 5/200/30 SCCM, and a total pressure of 1.5 Pa by Raman spectroscopy. The absolute density ofmore » hydrogen atoms and the behavior of higher radicals and molecules in the mixture gas were evaluated using vacuum ultraviolet absorption spectroscopy and quadrupole mass spectrometer, respectively. H atom densities were of the order of 10{sup 11} cm{sup -3}. The fraction of H atom density increased, while higher radicals and molecules decreased with decrease in the total pressure. The increase in H atom density and decrease in higher radicals and molecules improved the crystallinity of films in low pressures below 10 Pa.« less

  2. Effect of a barley-vegetable soup on plasma carotenoids and biomarkers of cardiovascular disease.

    PubMed

    Bacchetti, Tiziana; Tullii, Domenico; Masciangelo, Simona; Gesuita, Rosaria; Skrami, Edlira; Brugè, Francesca; Silvestri, Sonia; Orlando, Patrick; Tiano, Luca; Ferretti, Gianna

    2015-07-01

    Functional foods that provide benefits beyond their traditional nutritional value have attracted much interest. Aim of the study was to evaluate the nutritional and the functional properties of a frozen ready-to-eat soup containing barley and pigmented vegetables. Both glycaemic index and the glyceamic load of ready-to-eat soup were evaluated in vivo. Moreover the bioavailability of carotenoids (lutein and beta-carotene) and the effect on lipid profile and lipid peroxidation were studied in 38 volunteers whose diet was supplemented for two weeks with a daily portion (250 g) of the ready-to-eat soup. Plasma levels of carotenoids (lutein and beta-carotene) and plasma total antioxidant capacity significantly increased after 2 weeks of treatment. Furthermore, we observed a decrease in the levels of lipids (total cholesterol and low density lipoprotein-cholesterol) and of markers of lipid peroxidation (oxidized low density lipoprotein and lipid hydroperoxides) in plasma of all subjects. The glyceamic index of the product was 36, therefore it could be considered a low glyceamic index food. An accurate selection of vegetable foods results in a palatable and healthy product that provides benefits on plasma lipids and lipid peroxidation (Protocol number 211525).

  3. Effect of a barley-vegetable soup on plasma carotenoids and biomarkers of cardiovascular disease

    PubMed Central

    Bacchetti, Tiziana; Tullii, Domenico; Masciangelo, Simona; Gesuita, Rosaria; Skrami, Edlira; Brugè, Francesca; Silvestri, Sonia; Orlando, Patrick; Tiano, Luca; Ferretti, Gianna

    2015-01-01

    Functional foods that provide benefits beyond their traditional nutritional value have attracted much interest. Aim of the study was to evaluate the nutritional and the functional properties of a frozen ready-to-eat soup containing barley and pigmented vegetables. Both glycaemic index and the glyceamic load of ready-to-eat soup were evaluated in vivo. Moreover the bioavailability of carotenoids (lutein and beta-carotene) and the effect on lipid profile and lipid peroxidation were studied in 38 volunteers whose diet was supplemented for two weeks with a daily portion (250 g) of the ready-to-eat soup. Plasma levels of carotenoids (lutein and beta-carotene) and plasma total antioxidant capacity significantly increased after 2 weeks of treatment. Furthermore, we observed a decrease in the levels of lipids (total cholesterol and low density lipoprotein-cholesterol) and of markers of lipid peroxidation (oxidized low density lipoprotein and lipid hydroperoxides) in plasma of all subjects. The glyceamic index of the product was 36, therefore it could be considered a low glyceamic index food. An accurate selection of vegetable foods results in a palatable and healthy product that provides benefits on plasma lipids and lipid peroxidation (Protocol number 211525). PMID:26236103

  4. α-Lipoic acid reduced weight gain and improved the lipid profile in rats fed with high fat diet.

    PubMed

    Seo, Eun Young; Ha, Ae Wha; Kim, Woo Kyoung

    2012-06-01

    The purpose of this study was to investigate the effects of α-lipoic acid on body weight and lipid profiles in Sprague-Dawley rats fed a high fat diet (HFD). After 4 weeks of feeding, rats on the HFD were divided into three groups by randomized block design; the first group received the high-fat-diet (n = 10), and the second group received the HFD administered with 0.25% α-lipoic acid (0.25LA), and the third group received the high-fat diet with 0.5% α-lipoic acid (0.5LA). The high fat diet with α-lipoic acid supplemented groups had significantly inhibited body weight gain, compared to that in the HFD group (P < 0.05). Organ weights of rats were also significantly reduced in liver, kidney, spleen, and visible fat tissues in rats supplemented with α-lipoic acid (P < 0.05). Significant differences in plasma lipid profiles, such as total lipids, total cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein, were observed between the HFD and 0.5LA groups. The atherogenic index and the plasma high density lipoprotein-cholesterol/total cholesterol ratio improved significantly with α-lipoic acid supplementation in a dose-dependent manner (P < 0.05). Total hepatic cholesterol and total lipid concentration decreased significantly in high fat fed rats supplemented with α-lipoic acid in a dose-dependent manner (P < 0.05), whereas liver triglyceride content was not affected. In conclusion, α-lipoic acid supplementation had a positive effect on weight gain and plasma and liver lipid profiles in rats.

  5. Ideal laser-beam propagation through high-temperature ignition Hohlraum plasmas.

    PubMed

    Froula, D H; Divol, L; Meezan, N B; Dixit, S; Moody, J D; Neumayer, P; Pollock, B B; Ross, J S; Glenzer, S H

    2007-02-23

    We demonstrate that a blue (3omega, 351 nm) laser beam with an intensity of 2 x 10(15) W cm(-2) propagates nearly within the original beam cone through a millimeter scale, T(e)=3.5 keV high density (n(e)=5 x 10(20) cm(-3)) plasma. The beam produced less than 1% total backscatter at these high temperatures and densities; the resulting transmission is greater than 90%. Scaling of the electron temperature in the plasma shows that the plasma becomes transparent for uniform electron temperatures above 3 keV. These results are consistent with linear theory thresholds for both filamentation and backscatter instabilities inferred from detailed hydrodynamic simulations. This provides a strong justification for current inertial confinement fusion designs to remain below these thresholds.

  6. Early Fluid and Protein Shifts in Men During Water Immersion

    NASA Technical Reports Server (NTRS)

    Hinghofer-Szalkay, H.; Harrison, M. H.; Greenleaf, J. E.

    1987-01-01

    High precision blood and plasma densitometry was used to measure transvascular fluid shifts during water immersion to the neck. Six men (28-49 years) undertook 30 min of standing immersion in water at 35.0 +/- 0.2 C; immersion was preceded by 30 min control standing in air at 28 +/- 1 C. Blood was sampled from an antecubital catheter for determination of Blood Density (BD), Plasma Density (PD), Haematocrit (Ht), total Plasma Protein Concentration (PPC), and Plasma Albumin Concentration (PAC). Compared to control, significant decreases (p less than 0.01) in all these measures were observed after 20 min immersion. At 30 min, plasma volume had increased by 11.0 +/- 2.8%; the average density of the fluid shifted from extravascular fluid into the vascular compartment was 1006.3 g/l; albumin moved with the fluid and its albumin concentration was about one-third of the plasma protein concentration during early immersion. These calculations are based on the assumption that the F-cell ratio remained unchanged. No changes in erythrocyte water content during immersion were found. Thus, immersion-induced haemodilution is probably accompanied by protein (mainly albumin) augmentation which accompanies the intra-vascular fluid shift.

  7. The Radio Plasma Imager Investigation on the IMAGE Spacecraft

    NASA Technical Reports Server (NTRS)

    Reinisch, Bodo W.; Haines, D. M.; Bibl, K.; Cheney, G.; Galkin, I. A.; Huang, X.; Myers, S. H.; Sales, G. S.; Benson, R. F.; Fung, S. F.

    1999-01-01

    Radio plasma imaging uses total reflection of electromagnetic waves from plasmas whose plasma frequencies equal the radio sounding frequency and whose electron density gradients are parallel to the wave normals. The Radio Plasma Imager (RPI) has two orthogonal 500-m long dipole antennas in the spin plane for near omni-directional transmission. The third antenna is a 20-m dipole. Echoes from the magnetopause, plasmasphere and cusp will be received with three orthogonal antennas, allowing the determination of their angle-of-arrival. Thus it will be possible to create image fragments of the reflecting density structures. The instrument can execute a large variety of programmable measuring programs operating at frequencies between 3 kHz and 3 MHz. Tuning of the transmit antennas provides optimum power transfer from the 10 W transmitter to the antennas. The instrument can operate in three active sounding modes: (1) remote sounding to probe magnetospheric boundaries, (2) local (relaxation) sounding to probe the local plasma, and (3) whistler stimulation sounding. In addition, there is a passive mode to record natural emissions, and to determine the local electron density and temperature by using a thermal noise spectroscopy technique.

  8. Absolute atomic oxygen density measurements for nanosecond-pulsed atmospheric-pressure plasma jets using two-photon absorption laser-induced fluorescence spectroscopy

    NASA Astrophysics Data System (ADS)

    Jiang, C.; Carter, C.

    2014-12-01

    Nanosecond-pulsed plasma jets that are generated under ambient air conditions and free from confinement of electrodes have become of great interest in recent years due to their promising applications in medicine and dentistry. Reactive oxygen species that are generated by nanosecond-pulsed, room-temperature non-equilibrium He-O2 plasma jets among others are believed to play an important role during the bactericidal or sterilization processes. We report here absolute measurements of atomic oxygen density in a 1 mm-diameter He/(1%)O2 plasma jet at atmospheric pressure using two-photon absorption laser-induced fluorescence spectroscopy. Oxygen number density on the order of 1013 cm-3 was obtained in a 150 ns, 6 kV single-pulsed plasma jet for an axial distance up to 5 mm above the device nozzle. Temporally resolved O density measurements showed that there are two maxima, separated in time by 60-70 µs, and a total pulse duration of 260-300 µs. Electrostatic modeling indicated that there are high-electric-field regions near the nozzle exit that may be responsible for the observed temporal behavior of the O production. Both the field-distribution-based estimation of the time interval for the O number density profile and a pulse-energy-dependence study confirmed that electric-field-dependent, direct and indirect electron-induced processes play important roles for O production.

  9. Gamma-glutamyltransferase fractions in human plasma and bile: characteristic and biogenesis.

    PubMed

    Fornaciari, Irene; Fierabracci, Vanna; Corti, Alessandro; Aziz Elawadi, Hassan; Lorenzini, Evelina; Emdin, Michele; Paolicchi, Aldo; Franzini, Maria

    2014-01-01

    Total plasma gamma-glutamyltransferase (GGT) activity is a sensitive, non-specific marker of liver dysfunction. Four GGT fractions (b-, m-, s-, f-GGT) were described in plasma and their differential specificity in the diagnosis of liver diseases was suggested. Nevertheless fractional GGT properties have not been investigated yet. The aim of this study was to characterize the molecular nature of fractional GGT in both human plasma and bile. Plasma was obtained from healthy volunteers; whereas bile was collected from patients undergoing liver transplantation. Molecular weight (MW), density, distribution by centrifugal sedimentation and sensitivity to both detergent (deoxycholic acid) and protease (papain) were evaluated. A partial purification of b-GGT was obtained by ultracentrifugation. Plasma b-GGT fraction showed a MW of 2000 kDa and a density between 1.063-1.210 g/ml. Detergent converted b-GGT into s-GGT, whereas papain alone did not produce any effect. Plasma m-GGT and s-GGT showed a MW of 1,000 and 200 kDa, and densities between 1.006-1.063 g/ml and 1.063-1.210 g/ml respectively. Both fractions were unaffected by deoxycholic acid, while GGT activity was recovered into f-GGT peak after papain treatment. Plasma f-GGT showed a MW of 70 kDa and a density higher than 1.21 g/ml. We identified only two chromatographic peaks, in bile, showing similar characteristics as plasma b- and f-GGT fractions. These evidences, together with centrifugal sedimentation properties and immunogold electronic microscopy data, indicate that b-GGT is constituted of membrane microvesicles in both bile and plasma, m-GGT and s-GGT might be constituted of bile-acid micelles, while f-GGT represents the free-soluble form of the enzyme.

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Taroyan, Youra; Williams, Thomas

    The interaction of an intergranular downdraft with an embedded vertical magnetic field is examined. It is demonstrated that the downdraft may couple to small magnetic twists leading to an instability. The descending plasma exponentially amplifies the magnetic twists when it decelerates with depth due to increasing density. Most efficient amplification is found in the vicinity of the level, where the kinetic energy density of the downdraft reaches equipartition with the magnetic energy density. Continual extraction of energy from the decelerating plasma and growth in the total azimuthal energy occurs as a consequence of the wave-flow coupling along the downdraft. Themore » presented mechanism may drive vortices and torsional motions that have been detected between granules and in simulations of magnetoconvection.« less

  11. Pressure profiles of plasmas confined in the field of a dipole magnet

    NASA Astrophysics Data System (ADS)

    Davis, Matthew Stiles

    Understanding the maintenance and stability of plasma pressure confined by a strong magnetic field is a fundamental challenge in both laboratory and space plasma physics. Using magnetic and X-ray measurements on the Levitated Dipole Experiment (LDX), the equilibrium plasma pressure has been reconstructed, and variations of the plasma pressure for different plasma conditions have been examined. The relationship of these profiles to the magnetohydrodynamic (MHD) stability limit, and to the enhanced stability limit that results from a fraction of energetic trapped electrons, has been analyzed. In each case, the measured pressure profiles and the estimated fractional densities of energetic electrons were qualitatively consistent with expectations of plasma stability. LDX confines high temperature and high pressure plasma in the field of a superconducting dipole magnet. The strong dipole magnet can be either mechanically supported or magnetically levitated. When the dipole was mechanically supported, the plasma density profile was generally uniform while the plasma pressure was highly peaked. The uniform density was attributed to the thermal plasma being rapidly lost along the field to the mechanical supports. In contrast, the strongly peaked plasma pressure resulted from a fraction of energetic, mirror trapped electrons created by microwave heating at the electron cyclotron resonance (ECRH). These hot electrons are known to be gyrokinetically stabilized by the background plasma and can adopt pressure profiles steeper than the MHD limit. X-ray measurements indicated that this hot electron population could be described by an energy distribution in the range 50-100 keV. Combining information from the magnetic reconstruction of the pressure profile, multi-chord interferometer measurements of the electron density profile, and X-ray measurements of the hot electron energy distribution, the fraction of energetic electrons at the pressure peak was estimated to be ˜ 35% of the total electron population. When the dipole was magnetically levitated the plasma density increased substantially because particle losses to the mechanical supports were eliminated so particles could only be lost via slower cross-field transport processes. The pressure profile was observed to be broader during levitated operation than it was during supported operation, and the pressure appeared to be contained in both a thermal population and an energetic electron population. X-ray spectra indicated that the X-rays came from a similar hot electron population during levitated and supported operation; however, the hot electron fraction was an order of magnitude smaller during levitated operation (<3% of the total electron population). Pressure gradients for both supported and levitated plasmas were compared to the MHD limit. Levitated plasmas had pressure profiles that were (i) steeper than, (ii) shallower than, or (iii) near the MHD limit dependent on plasma conditions. However, those profiles that exceeded the MHD limit were observed to have larger fractions of energetic electrons. When the dipole magnet was supported, high pressure plasmas always had profiles that exceeded the MHD interchange stability limit, but the high pressure in these plasmas appeared to arise entirely from a population of energetic trapped electrons.

  12. Effect of the target power density on high-power impulse magnetron sputtering of copper

    NASA Astrophysics Data System (ADS)

    Kozák, Tomáš

    2012-04-01

    We present a model analysis of high-power impulse magnetron sputtering of copper. We use a non-stationary global model based on the particle and energy conservation equations in two zones (the high density plasma ring above the target racetrack and the bulk plasma region), which makes it possible to calculate time evolutions of the averaged process gas and target material neutral and ion densities, as well as the fluxes of these particles to the target and substrate during a pulse period. We study the effect of the increasing target power density under conditions corresponding to a real experimental system. The calculated target current waveforms show a long steady state and are in good agreement with the experimental results. For an increasing target power density, an analysis of the particle densities shows a gradual transition to a metal dominated discharge plasma with an increasing degree of ionization of the depositing flux. The average fraction of target material ions in the total ion flux onto the substrate is more than 90% for average target power densities higher than 500 W cm-2 in a pulse. The average ionized fraction of target material atoms in the flux onto the substrate reaches 80% for a maximum average target power density of 3 kW cm-2 in a pulse.

  13. Phase mixing of Alfvén waves in axisymmetric non-reflective magnetic plasma configurations

    NASA Astrophysics Data System (ADS)

    Petrukhin, N. S.; Ruderman, M. S.; Shurgalina, E. G.

    2018-02-01

    We study damping of phase-mixed Alfvén waves propagating in non-reflective axisymmetric magnetic plasma configurations. We derive the general equation describing the attenuation of the Alfvén wave amplitude. Then we applied the general theory to a particular case with the exponentially divergent magnetic field lines. The condition that the configuration is non-reflective determines the variation of the plasma density along the magnetic field lines. The density profiles exponentially decreasing with the height are not among non-reflective density profiles. However, we managed to find non-reflective profiles that fairly well approximate exponentially decreasing density. We calculate the variation of the total wave energy flux with the height for various values of shear viscosity. We found that to have a substantial amount of wave energy dissipated at the lower corona, one needs to increase shear viscosity by seven orders of magnitude in comparison with the value given by the classical plasma theory. An important result that we obtained is that the efficiency of the wave damping strongly depends on the density variation with the height. The stronger the density decrease, the weaker the wave damping is. On the basis of this result, we suggested a physical explanation of the phenomenon of the enhanced wave damping in equilibrium configurations with exponentially diverging magnetic field lines.

  14. Detailed Experimental Study of Ion Acceleration by Interaction of an Ultra-Short Intense Laser with an Underdense Plasma

    PubMed Central

    Kahaly, S.; Sylla, F.; Lifschitz, A.; Flacco, A.; Veltcheva, M.; Malka, V.

    2016-01-01

    Ion acceleration from intense (Iλ2 > 1018 Wcm−2 μm2) laser-plasma interaction is experimentally studied within a wide range of He gas densities. Focusing an ultrashort pulse (duration  ion plasma period) on a newly designed submillimetric gas jet system, enabled us to inhibit total evacuation of electrons from the central propagation channel reducing the radial ion acceleration associated with ponderomotive Coulomb explosion, a mechanism predominant in the long pulse scenario. New ion acceleration mechanism have been unveiled in this regime leading to non-Maxwellian quasi monoenergetic features in the ion energy spectra. The emitted nonthermal ion bunches show a new scaling of the ion peak energy with plasma density. The scaling identified in this new regime differs from previously reported studies. PMID:27531755

  15. Repetition rate dependency of low-density plasma effects during femtosecond-laser-based surgery of biological tissue

    NASA Astrophysics Data System (ADS)

    Kuetemeyer, K.; Baumgart, J.; Lubatschowski, H.; Heisterkamp, A.

    2009-11-01

    Femtosecond laser based nanosurgery of biological tissue is usually done in two different regimes. Depending on the application, low kHz repetition rates above the optical breakdown threshold or high MHz repetition rates in the low-density plasma regime are used. In contrast to the well understood optical breakdown, mechanisms leading to dissection below this threshold are not well known due to the complexity of chemical effects with high numbers of interacting molecules. Furthermore, the laser repetition rate may influence their efficiency. In this paper, we present our study on low-density plasma effects in biological tissue depending on repetition rate by static exposure of porcine corneal stroma to femtosecond pulses. We observed a continuous increase of the laser-induced damage with decreasing repetition rate over two orders of magnitude at constant numbers of applied laser pulses or constant laser pulse energies. Therefore, low repetition rates in the kHz regime are advantageous to minimize the total delivered energy to biological tissue during femtosecond laser irradiation. However, due to frequent excessive damage in this regime directly above the threshold, MHz repetition rates are preferable to create nanometer-sized cuts in the low-density plasma regime.

  16. Supersonic molecular beam injection effects on tokamak plasma applied non-axisymmetric magnetic perturbation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Han, Hyunsun, E-mail: hyunsun@nfri.re.kr; In, Y.; Jeon, Y. M.

    The change of tokamak plasma behavior by supersonic molecular beam injection (SMBI) was investigated by applying a three-dimensional magnetic perturbation that could suppress edge localized modes (ELMs). From the time trace of decreasing electron temperature and with increasing plasma density keeping the total confined energy constant, the SMBI seems to act as a cold pulse on the plasma. However, the ELM behaviors were changed drastically (i.e., the symptom of ELM suppression has disappeared). The plasma collisionality in the edge-pedestal region could play a role in the change of the ELM behaviors.

  17. Elevated plasma low-density lipoprotein and high-density lipoprotein cholesterol levels in amenorrheic athletes: effects of endogenous hormone status and nutrient intake.

    PubMed

    Friday, K E; Drinkwater, B L; Bruemmer, B; Chesnut, C; Chait, A

    1993-12-01

    To determine the interactive effects of hormones, exercise, and diet on plasma lipids and lipoproteins, serum estrogen and progesterone levels, nutrient intake, and plasma lipid, lipoprotein, and apolipoprotein concentrations were measured in 24 hypoestrogenic amenorrheic and 44 eumenorrheic female athletes. When compared to eumenorrheic athletes, amenorrheic athletes had higher levels of plasma cholesterol (5.47 +/- 0.17 vs. 4.84 +/- 0.12 mmol/L, P = 0.003), triglyceride (0.75 +/- 0.06 vs. 0.61 +/- 0.03 mmol/L, P = 0.046), low-density lipoprotein (LDL; 3.16 +/- 0.15 vs. 2.81 +/- 0.09 mmol/L, P = 0.037), high-density lipoprotein (HDL; 1.95 +/- 0.07 vs. 1.73 +/- 0.05 mmol/L, P = 0.007), and HDL2 (0.84 +/- 0.06 vs. 0.68 +/- 0.04 mmol/L, P = 0.02) cholesterol. Plasma LDL/HDL cholesterol ratios, very low-density lipoprotein and HDL3 cholesterol, and apolipoprotein A-I and A-II levels were similar in the two groups. Amenorrheic athletes consumed less fat than eumenorrheic subjects (52 +/- 5 vs. 75 +/- 3 g/day, P = 0.02), but similar amounts of calories, cholesterol, protein, carbohydrate, and ethanol. HDL cholesterol levels in amenorrheic subjects correlated positively with the percent of dietary calories from fat (r = 0.42, n = 23, P = 0.045) but negatively with the percent from protein (r = -0.49, n = 23, P = 0.017). Thus, exercise-induced amenorrhea may adversely affect cardiovascular risk by increasing plasma LDL and total cholesterol. However, cardioprotective elevations in plasma HDL and HDL2 cholesterol may neutralize the risk of cardiovascular disease in amenorrheic athletes.

  18. Turbulent fluctuations during pellet injection into a dipole confined plasma torus

    NASA Astrophysics Data System (ADS)

    Garnier, D. T.; Mauel, M. E.; Roberts, T. M.; Kesner, J.; Woskov, P. P.

    2017-01-01

    We report measurements of the turbulent evolution of the plasma density profile following the fast injection of lithium pellets into the Levitated Dipole Experiment (LDX) [Boxer et al., Nat. Phys. 6, 207 (2010)]. As the pellet passes through the plasma, it provides a significant internal particle source and allows investigation of density profile evolution, turbulent relaxation, and turbulent fluctuations. The total electron number within the dipole plasma torus increases by more than a factor of three, and the central density increases by more than a factor of five. During these large changes in density, the shape of the density profile is nearly "stationary" such that the gradient of the particle number within tubes of equal magnetic flux vanishes. In comparison to the usual case, when the particle source is neutral gas at the plasma edge, the internal source from the pellet causes the toroidal phase velocity of the fluctuations to reverse and changes the average particle flux at the plasma edge. An edge particle source creates an inward turbulent pinch, but an internal particle source increases the outward turbulent particle flux. Statistical properties of the turbulence are measured by multiple microwave interferometers and by an array of probes at the edge. The spatial structures of the largest amplitude modes have long radial and toroidal wavelengths. Estimates of the local and toroidally averaged turbulent particle flux show intermittency and a non-Gaussian probability distribution function. The measured fluctuations, both before and during pellet injection, have frequency and wavenumber dispersion consistent with theoretical expectations for interchange and entropy modes excited within a dipole plasma torus having warm electrons and cool ions.

  19. Developing the science and technology for the Material Plasma Exposure eXperiment

    NASA Astrophysics Data System (ADS)

    Rapp, J.; Biewer, T. M.; Bigelow, T. S.; Caneses, J. F.; Caughman, J. B. O.; Diem, S. J.; Goulding, R. H.; Isler, R. C.; Lumsdaine, A.; Beers, C. J.; Bjorholm, T.; Bradley, C.; Canik, J. M.; Donovan, D.; Duckworth, R. C.; Ellis, R. J.; Graves, V.; Giuliano, D.; Green, D. L.; Hillis, D. L.; Howard, R. H.; Kafle, N.; Katoh, Y.; Lasa, A.; Lessard, T.; Martin, E. H.; Meitner, S. J.; Luo, G.-N.; McGinnis, W. D.; Owen, L. W.; Ray, H. B.; Shaw, G. C.; Showers, M.; Varma, V.; the MPEX Team

    2017-11-01

    Linear plasma generators are cost effective facilities to simulate divertor plasma conditions of present and future fusion reactors. They are used to address important R&D gaps in the science of plasma material interactions and towards viable plasma facing components for fusion reactors. Next generation plasma generators have to be able to access the plasma conditions expected on the divertor targets in ITER and future devices. The steady-state linear plasma device MPEX will address this regime with electron temperatures of 1-10 eV and electron densities of 1021{\\text{}}-1020 m-3 . The resulting heat fluxes are about 10 MW m-2 . MPEX is designed to deliver those plasma conditions with a novel Radio Frequency plasma source able to produce high density plasmas and heat electron and ions separately with electron Bernstein wave (EBW) heating and ion cyclotron resonance heating with a total installed power of 800 kW. The linear device Proto-MPEX, forerunner of MPEX consisting of 12 water-cooled copper coils, has been operational since May 2014. Its helicon antenna (100 kW, 13.56 MHz) and EC heating systems (200 kW, 28 GHz) have been commissioned and 14 MW m-2 was delivered on target. Furthermore, electron temperatures of about 20 eV have been achieved in combined helicon and ECH heating schemes at low electron densities. Overdense heating with EBW was achieved at low heating powers. The operational space of the density production by the helicon antenna was pushed up to 1.1 × 1020 m-3 at high magnetic fields of 1.0 T at the target. The experimental results from Proto-MPEX will be used for code validation to enable predictions of the source and heating performance for MPEX. MPEX, in its last phase, will be capable to expose neutron-irradiated samples. In this concept, targets will be irradiated in ORNL’s High Flux Isotope Reactor and then subsequently exposed to fusion reactor relevant plasmas in MPEX.

  20. Therapeutic effect of probiotic dahi on plasma, aortic, and hepatic lipid profile of hypercholesterolemic rats.

    PubMed

    Mohania, Dheeraj; Kansal, Vinod Kumar; Shah, Dilip; Nagpal, Ravinder; Kumar, Manoj; Gautam, Sanjeev Kumar; Singh, Birbal; Behare, Pradip Vishnu

    2013-09-01

    This study examined the effects of probiotic dahi prepared by Lactobacillus plantarum Lp9 and dahi culture in buffalo milk on lowering cholesterol in rats fed a hypercholesterolemic basal diet. Male Wistar rats were divided into 3 groups and fed with probiotic dahi, dahi, or buffalo milk for 120 days. Following the consumption of supplements (probiotic dahi, dahi or buffalo milk), the animals were fed a basal hypercholesterolemic diet. Plasma total cholesterol and triglycerides (TAGs) were decreased by 35% and 72% in rats fed with probiotic dahi group, while cholesterol levels increased by 70% and TAGs increased by 97% in buffalo milk and 59% in dahi fed groups. Supplementation of probiotic dahi further lowered plasma low-density lipoprotein (LDL) + very-low-density lipoprotein (VLDL)- cholesterol by 59%, while it elevated plasma high-density lipoprotein (HDL)-cholesterol by 116%. As a result, atherogenic index, the ratio of HDL to LDL + VLDL was markedly improved. Deposition of cholesterol and TAGs in liver and aorta were significantly reduced in rats fed with probiotic dahi. These observations suggest that probiotic dahi may have therapeutic potential to decrease plasma, hepatic and aortic lipid profile, and attenuate diet-induced hypercholesterolemia.

  1. Comparison of 2D simulations of detached divertor plasmas with divertor Thomson measurements in the DIII-D tokamak

    DOE PAGES

    Rognlien, Thomas D.; McLean, Adam G.; Fenstermacher, Max E.; ...

    2017-01-27

    A modeling study is reported using new 2D data from DIII-D tokamak divertor plasmas and improved 2D transport model that includes large cross-field drifts for the numerically difficult H-mode regime. The data set, which spans a range of plasmas densities for both forward and reverse toroidal magnetic field (B t) over a range of plasma densities, is provided by divertor Thomson scattering (DTS). Measurements utilizing X-point sweeping give corresponding 2D profiles of electron temperature (T e) and density (n e) across both divertor legs for individual discharges. The calculations show the same features of in/out plasma asymmetries as measured inmore » the experiment, with the normal B t direction (ion ∇B drift toward the X-point) having higher n e and lower T e in the inner divertor leg than outer. Corresponding emission data for total radiated power shows a strong inner-divertor/outer-divertor asymmetry that is reproduced by the simulations. Furthermore, these 2D UEDGE transport simulations are enabled for steep-gradient H-mode conditions by newly implemented algorithms to control isolated grid-scale irregularities.« less

  2. Association between plant-based diets and plasma lipids: a systematic review and meta-analysis.

    PubMed

    Yokoyama, Yoko; Levin, Susan M; Barnard, Neal D

    2017-09-01

    Although a recent meta-analysis of randomized controlled trials showed that adoption of a vegetarian diet reduces plasma lipids, the association between vegetarian diets and long-term effects on plasma lipids has not been subjected to meta-analysis. The aim was to conduct a systematic review and meta-analysis of observational studies and clinical trials that have examined associations between plant-based diets and plasma lipids. MEDLINE, Web of Science, and the Cochrane Central Register of Controlled Trials were searched for articles published in English until June 2015. The literature was searched for controlled trials and observational studies that investigated the effects of at least 4 weeks of a vegetarian diet on plasma lipids. Two reviewers independently extracted the study methodology and sample size, the baseline characteristics of the study population, and the concentrations and variance measures of plasma lipids. Mean differences in concentrations of plasma lipids between vegetarian and comparison diet groups were calculated. Data were pooled using a random-effects model. Of the 8385 studies identified, 30 observational studies and 19 clinical trials met the inclusion criteria (N = 1484; mean age, 48.6 years). Consumption of vegetarian diets was associated with lower mean concentrations of total cholesterol (-29.2 and -12.5 mg/dL, P < 0.001), low-density lipoprotein cholesterol (-22.9 and -12.2 mg/dL, P < 0.001), and high-density lipoprotein cholesterol (-3.6 and -3.4 mg/dL, P < 0.001), compared with consumption of omnivorous diets in observational studies and clinical trials, respectively. Triglyceride differences were -6.5 (P = 0.092) in observational studies and 5.8 mg/dL (P = 0.090) in intervention trials. Plant-based diets are associated with decreased total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol, but not with decreased triglycerides. PROSPERO number CRD42015023783. Available at: https://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42015023783. © The Author(s) 2017. Published by Oxford University Press on behalf of the International Life Sciences Institute.

  3. Association between plant-based diets and plasma lipids: a systematic review and meta-analysis

    PubMed Central

    Yokoyama, Yoko; Levin, Susan M; Barnard, Neal D

    2017-01-01

    Abstract Context Although a recent meta-analysis of randomized controlled trials showed that adoption of a vegetarian diet reduces plasma lipids, the association between vegetarian diets and long-term effects on plasma lipids has not been subjected to meta-analysis. Objective The aim was to conduct a systematic review and meta-analysis of observational studies and clinical trials that have examined associations between plant-based diets and plasma lipids. Data Sources MEDLINE, Web of Science, and the Cochrane Central Register of Controlled Trials were searched for articles published in English until June 2015. Study Selection The literature was searched for controlled trials and observational studies that investigated the effects of at least 4 weeks of a vegetarian diet on plasma lipids. Data Extraction Two reviewers independently extracted the study methodology and sample size, the baseline characteristics of the study population, and the concentrations and variance measures of plasma lipids. Mean differences in concentrations of plasma lipids between vegetarian and comparison diet groups were calculated. Data were pooled using a random-effects model. Results Of the 8385 studies identified, 30 observational studies and 19 clinical trials met the inclusion criteria (N = 1484; mean age, 48.6 years). Consumption of vegetarian diets was associated with lower mean concentrations of total cholesterol (−29.2 and −12.5 mg/dL, P < 0.001), low-density lipoprotein cholesterol (−22.9 and −12.2 mg/dL, P < 0.001), and high-density lipoprotein cholesterol (−3.6 and −3.4 mg/dL, P < 0.001), compared with consumption of omnivorous diets in observational studies and clinical trials, respectively. Triglyceride differences were −6.5 (P = 0.092) in observational studies and 5.8 mg/dL (P = 0.090) in intervention trials. Conclusions Plant-based diets are associated with decreased total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol, but not with decreased triglycerides. Systematic Review Registration PROSPERO number CRD42015023783. Available at: https://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42015023783. PMID:28938794

  4. Characterization of Ni-YSZ anodes for solid oxide fuel cells fabricated by suspension plasma spraying with axial feedstock injection

    NASA Astrophysics Data System (ADS)

    Metcalfe, Craig; Kuhn, Joel; Kesler, Olivera

    2013-12-01

    Composite Ni-Y0.15Zr0.85O1.925 anodes were fabricated by axial-injection suspension plasma spraying in open atmosphere conditions. The composition of the anode is controllable by adjustment of the plasma gas composition, stand-off distance, and suspension feed rate. The total porosity is controllable through the addition of carbon black to the suspension as a sacrificial pore-forming material as well as by adjustment of the suspension feed rate. The size of the NiO particles in suspension affects both the composition and total porosity, with larger NiO particles leading to increased Ni content and porosity in the deposited coatings. The surface roughness increases with a decrease of the in-flight droplet momentum, which results from both smaller NiO particles in suspension and the addition of low density pore-forming materials. A solid oxide fuel cell was fabricated with both electrodes and electrolyte fabricated by axial-injection plasma spraying. Peak power densities of 0.718 W cm-2 and 1.13 W cm-2 at 750 °C and 850 °C, respectively, were achieved.

  5. Size-controlled growth and antibacterial mechanism for Cu:C nanocomposite thin films.

    PubMed

    Javid, Amjed; Kumar, Manish; Yoon, Seokyoung; Lee, Jung Heon; Han, Jeon Geon

    2016-12-21

    The interdependence of 'size' and 'volume-fraction' hinders the identification of their individual role in the interface properties of metal nanoparticles (NPs) embedded in a matrix. Here, the case of Cu NPs embedded in a C matrix is presented for their profound antibacterial activity. Cu:C nanocomposite thin films with fixed Cu content (≈12 atomic%) are prepared using a plasma process where plasma energy controls the size of Cu NPs (from 9 nm to 16 nm). An inverse relationship between the size-effect on antibacterial activity against Escherichia coli and Staphylococcus aureus bacteria is established through the real time monitoring of an aliquot by inductively coupled plasma mass spectrometry, which confirmed the inverse relationship of Cu ion release from the nanocomposite with varied Cu NP sizes. It was found that enhancing the total power density increases the plasma density as well as effective kinetic energy of the plasma species, which in turn creates a large number of nucleation sites and restricts the island kind of growth of Cu NPs. The mechanism of NP size-control is illustrated on the basis of ion density and nucleation and the growth regime of plasma species. This physical approach to NP size reduction anticipates a contamination-free competitive recipe of size-control to capping based chemical methods.

  6. Insulin-like growth factor-1, insulin-like growth factor-binding protein-3, growth hormone, and mammographic density in the Nurses' Health Studies.

    PubMed

    Rice, Megan S; Tworoger, Shelley S; Rosner, Bernard A; Pollak, Michael N; Hankinson, Susan E; Tamimi, Rulla M

    2012-12-01

    Higher circulating insulin-like growth factor I (IGF-1) levels have been associated with higher mammographic density among women in some, but not all studies. Also, few studies have examined the association between mammographic density and circulating growth hormone (GH) in premenopausal women. We conducted a cross-sectional study among 783 premenopausal women and 436 postmenopausal women who were controls in breast cancer case-control studies nested in the Nurses' Health Study (NHS) and NHSII. Participants provided blood samples in 1989-1990 (NHS) or in 1996-1999 (NHSII), and mammograms were obtained near the time of blood draw. Generalized linear models were used to assess the associations of IGF-1, IGF-binding protein-3 (IGFBP-3), IGF-1:IGFBP-3 ratio, and GH with percent mammographic density, total dense area, and total non-dense area. Models were adjusted for potential confounders including age and body mass index (BMI), among others. We also assessed whether the associations varied by age or BMI. In both pre- and postmenopausal women, percent mammographic density was not associated with plasma levels of IGF-1, IGFBP-3, or the IGF-1:IGFBP-3 ratio. In addition, GH was not associated with percent density among premenopausal women in the NHSII. Similarly, total dense area and non-dense area were not significantly associated with any of these analytes. In postmenopausal women, IGF-1 was associated with higher percent mammographic density among women with BMI <25 kg/m(2), but not among overweight/obese women. Overall, plasma IGF-1, IGFBP-3, and GH levels were not associated with mammographic density in a sample of premenopausal and postmenopausal women.

  7. Conversion of α-linolenic acid to long-chain omega-3 fatty acid derivatives and alterations of HDL density subfractions and plasma lipids with dietary polyunsaturated fatty acids in Monk parrots (Myiopsitta monachus).

    PubMed

    Petzinger, C; Larner, C; Heatley, J J; Bailey, C A; MacFarlane, R D; Bauer, J E

    2014-04-01

    The effect of α-linolenic acid from a flaxseed (FLX)-enriched diet on plasma lipid and fatty acid metabolism and possible atherosclerosis risk factors was studied in Monk parrots (Myiopsitta monachus). Twenty-four Monk parrots were randomly assigned to diets containing either 10% ground SUNs or 10% ground FLXs. Feed intake was calculated daily. Blood samples, body condition scores and body weights were obtained at -5 weeks, day 0, 7, 14, 28, 42 and 70. Plasma samples were analysed for total cholesterol, free cholesterol, triacylglycerols and lipoproteins. Phospholipid subfraction fatty acid profiles were determined. By day 70, the FLX group had significantly higher plasma phospholipid fatty acids including 18:3n-3 (α-linolenic acid), 20:5n-3 (eicosapentaenoic acid) and 22:6n-3 (docosahexaenoic acid). The sunflower group had significantly higher plasma phospholipid levels of 20:4n-6 (arachidonic acid). By day 70, the high-density lipoprotein (HDL) peak shifted resulting in significantly different HDL peak densities between the two experimental groups (1.097 g/ml FLX group and 1.095 g/ml SUN group, p = 0.028). The plasma fatty acid results indicate that Monk parrots can readily convert α-linolenic acid to the long-chain omega-3 derivatives including docosahexaenoic acid and reduce 20:4n-6 accumulation in plasma phospholipids. The reason for a shift in the HDL peak density is unknown at this time. Journal of Animal Physiology and Animal Nutrition © 2013 Blackwell Verlag GmbH.

  8. Maternal plasma cholesterol and duration of pregnancy: A prospective cohort study in Ghana.

    PubMed

    Oaks, Brietta M; Stewart, Christine P; Laugero, Kevin D; Adu-Afarwuah, Seth; Lartey, Anna; Vosti, Stephen A; Ashorn, Per; Dewey, Kathryn G

    2017-10-01

    Low plasma cholesterol may be associated with preterm birth; however, results are mixed and limited primarily to high-income countries. Our objective was to determine whether maternal plasma lipid concentrations are associated with pregnancy duration. We performed a nested cohort (n = 320) study of pregnant Ghanaian women enrolled in a randomized controlled trial. Total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol, and triglyceride concentrations were analyzed in plasma at ≤20and 36 weeks gestation as continuous variables and also categorized into low, referent, or high (<10th, 10th-90th, >90th percentile). At ≤20 weeks, plasma lipid concentrations were not associated with pregnancy duration. At 36 weeks, total cholesterol and triglyceride concentrations were not associated with pregnancy duration. Higher HDL-C at 36 weeks was associated with a longer pregnancy duration (adjusted β-coefficient ± standard error: 0.05 ± 0.02 days mg -1 /dL, p = .02); pregnancy duration was 5.9 ± 2.0 (mean ± standard error) days shorter among women with low HDL-C compared with the referent group (10th-90th percentile) (p = .02) and 8.6 ± 2.6 days shorter when compared with the high HDL-C group (p = .003). Pregnancy duration was 4.9 ± 2.1 days longer among women with low low-density lipoprotein cholesterol at 36 weeks gestation when compared with the referent group (p = .051). Our data suggest that low HDL-C in the third trimester of pregnancy is associated with a shorter duration of pregnancy in this study population but do not support the hypothesis that low total cholesterol is associated with a shorter pregnancy duration. © 2016 John Wiley & Sons Ltd.

  9. Inductively coupled Cl2/Ar plasma: Experimental investigation and modeling

    NASA Astrophysics Data System (ADS)

    Efremov, A. M.; Kim, Dong-Pyo; Kim, Chang-Il

    2003-07-01

    Electrophysical and kinetic characteristics of Cl2/Ar plasma were investigated to understand the influence of the addition of Ar on the volume densities and fluxes of active particles, both neutral and charged. Our analysis combined both experimental methods and plasma modeling. It was found that addition of Ar to Cl2 leads to deformation of the electron energy distribution function and an increase of the electron mean energy due to the ``transparency'' effect. Direct electron impact dissociation of Cl2 molecules represents the main source of chlorine atoms in the plasma volume. The contributions of stepwise dissociation and ionization involving Ar metastable atoms were found to be negligible. Addition of Ar to Cl2 causes the decrease of both electron and ion densities due to a decrease in the total ionization rate and the acceleration of heterogeneous decay of charged particles.

  10. The Plasma Environment at Enceladus and Europa Compared

    NASA Astrophysics Data System (ADS)

    Rymer, Abigail; Persoon, Ann; Morooka, Michiko; Heuer, Steven; Westlake, Joseph H.

    2017-10-01

    The plasma environment near Enceladus is complex, as revealed during 16 encounters of the Cassini spacecraft. The well documented Enceladus plumes create a dusty, asymmetric exosphere in which electrons can attach to small ice particles - forming anions, and negatively charged nanograins and dust - to the extent that cations can be the lightest charged particles present and, as a result, the dominant current carriers. Several instruments on the Cassini spacecraft are able to measure this environment in both expected and unexpected ways. Cassini Plasma Spectrometer (CAPS) is designed and calibrated to measure the thermal plasma ions and electrons and also measures the energy/charge of charged nanograins when present. Cassini Radio Plasma Wave Sensor (RPWS) measures electron density as derived from the ‘upper hybrid frequency’ which is a function of the total free electron density and magnetic field strength and provides a vital ground truth measurement for Cassini calibration when the density is sufficiently high for it to be well measured. Cassini Langmuir Probe (LP) measures the electron density and temperature via direct current measurement, and both CAPS and LP can provide estimates for the spacecraft potential which we compare. The plasma environment near Europa is similarly complex and, although not so comprehensively equipped and hampered by the non-deployment of its high gain antenna, the Galileo spacecraft made similar measurements during 9 Europa flybys and recent observations have suggested that, like Enceladus, Europa might have active plume activity. We present a detailed comparison of data from the Cassini and Galileo sensors in order to assess the plasma environment observed by the different instruments, discuss what is consistent and otherwise, and the implications for the plasma environment at Enceladus and Europa in the context of work to date as well as implications for future studies.

  11. Operation Everest II. Plasma Lipid and Hormonal Responses

    DTIC Science & Technology

    1988-01-01

    cholesterol [TC] and high density lipoprotein cholesterol [ HDL -C] concentrations are shown in Fig 2. Pre-ascent...of altitude on fasting total cholesterol and high density lipoprotein ( HDL ) cholesterol concentrations. ** = p<O.Ol from 760 Torr Figure 3: The effect...157.7*9.7 mg/dl, decreased by 25% to .6 118.3*13.5 mg/dl following the 40-day exposure (p<O.Ol). High density lipoprotein [ HDL -C] levels

  12. Noninductive RF startup in CDX-U

    NASA Astrophysics Data System (ADS)

    Jones, B.; Majeski, R.; Efthimion, P.; Kaita, R.; Menard, J.; Munsat, T.; Takase, Y.

    1998-11-01

    For the spherical torus (ST) to prove viable as a reactor, it will be necessary to devise techniques for noninductive plasma startup. Initial studies of noninductive plasma initiation have been performed on CDX-U, using the 100 kW high harmonic fast wave (HHFW) system in combination with the 1 kW 2.45 GHz electron cyclotron heating system used for breakdown. Modest density (ne ~ 10^12 cm-3), low temperature (5 eV) plasmas were formed, but the density profile was peaked far off-axis, very near the HHFW antenna. High neutral fill pressures were also required. In upcoming experiments, up to 500 kW of low frequency RF power will utilized for heating and noninductive current drive in the mode conversion regime in a target noninductive plasma formed by a combination of 5.6 and 14 GHz ECH (40 kW total). Modeling will be presented which indicates that startup to plasma currents of 60 kA is feasible with this system.

  13. Plasma lipid levels of rats fed a diet containing pork fat as a source of lipids after splenic surgery.

    PubMed

    Dinis, Ana Paula Gonçalves; Marques, Ruy Garcia; Simões, Fernanda Correia; Diestel, Cristina Fajardo; Caetano, Carlos Eduardo Rodrigues; Secchin, Dióscuro José Ferreira; Neto, José Firmino Nogueira; Portela, Margareth Crisóstomo

    2009-06-01

    Experimental studies have suggested an important role of the spleen in lipid metabolism, although with controversial results. Our purpose was to analyze the effect of a nutritionally balanced (NB) diet and a diet containing pork fat (PF) as source of lipids on the lipid profile of rats submitted to splenic surgery. Sixty adult male Wistar rats were divided into six groups of 10 animals each: 1 sham-operated, NB diet; 2 sham-operated, PF diet; 3 total splenectomy (TS), NB diet; 4 TS, PF diet; 5 TS followed by splenic autotransplantation (SA), NB diet; and 6 SA, PF diet. Blood samples were collected at the beginning (D0) and after 12 weeks of the experiment (D + 12) for plasma lipid determination. Morphologic regeneration of splenic tissues was observed, with no differences between groups 5 and 6. When D + 12 plasma lipid levels were compared to D0 levels there were no differences in groups 1, 3, and 5, while in groups 2, 4, and 6 total cholesterol (TC), low density lipoprotein (LDL), very low density lipoprotein (VLDL), and triacylglycerols (TAG) increased, and high density lipoprotein (HDL) decreased. At D + 12, groups 2, 4, and 6 had lower HDL than group 3. In conclusion, regardless of the surgical procedure applied to the spleen, an NB diet maintained plasma lipid levels while a diet with PF as source of lipids changed the animals' lipid profile.

  14. Seasonal mercury exposure and oxidant-antioxidant status of James Bay sport fishermen.

    PubMed

    Bélanger, Marie-Claire; Mirault, Marc-Edouard; Dewailly, Eric; Plante, Michel; Berthiaume, Line; Noël, Micheline; Julien, Pierre

    2008-05-01

    The effects of a moderate seasonal exposure to methylmercury on plasma low-density lipoprotein (LDL) oxidation and cardiovascular risk indices are not known. The objective of the study was to assess the effects of a seasonal exposure to mercury at similar dose reported to increase cardiovascular risk through fish consumption. Effects on lipoprotein cholesterol and fatty acid profiles, LDL oxidation, and blood oxidant-antioxidant balance were to be assessed in sport fishermen presenting normal blood selenium and omega-3 fatty acid contents. Thirty-one healthy James Bay sport fishermen were assessed for within-subject longitudinal seasonal variations in hair and blood mercury, plasma oxidized LDL, lipophilic antioxidants, homocysteine, blood selenium, and glutathione peroxidase and reductase activities determined before and after the fishing season and compared by matched-pair tests. Hair mercury doubled during the fishing season (2.8+/-0.4 microg/g, P<.0001). Baseline blood selenium, homocysteine, and erythrocyte fatty acid profiles did not change. Plasma high-density lipoprotein cholesterol increased (+5%, P=.05), whereas very low-density lipoprotein cholesterol and oxidized LDL decreased (-8%, P=.05; -18%, P=.008). Blood glutathione peroxidase (+9.7%, P=.001), glutathione reductase (+7.2%, P<.0001), and total glutathione (+45% P<.0001) increased during the fishing season. Plasma total coenzyme Q10 (+13%, P=.02), ubiquinone-10 (+67%, P=.03), and beta-carotene (+46%, P=.01) also increased, whereas vitamin E status was unaffected. Pairwise correlations revealed no association between mercury exposure and any of the biomarkers investigated. In contrast, strong predictors of cardiovascular risk such as high-density lipoprotein cholesterol, oxidized LDL, and glutathione peroxidase improved during the fishing season despite elevated methylmercury exposure. The beneficial effects of seasonal fishing activity and fish consumption on cardiovascular health may suppress detrimental effects of concomitant moderate methylmercury exposure.

  15. Equatorial Ionospheric Disturbance Field-Aligned Plasma Drifts Observed by C/NOFS

    NASA Astrophysics Data System (ADS)

    Zhang, Ruilong; Liu, Libo; Balan, N.; Le, Huijun; Chen, Yiding; Zhao, Biqiang

    2018-05-01

    Using C/NOFS satellite observations, this paper studies the disturbance field-aligned plasma drifts in the equatorial topside ionosphere during eight geomagnetic storms in 2011-2015. During all six storms occurred in the solstices, the disturbance field-aligned plasma drift is from winter to summer hemisphere especially in the morning-midnight local time sector and the disturbance is stronger in June solstice. The two storms occurred at equinoxes have very little effect on the field-aligned plasma drift. Using the plasma temperature data from DMSP satellites and Global Positioning System-total electron content, it is suggested that the plasma density gradient seems likely to cause the disturbance winter-to-summer plasma drift while the role of plasma temperature gradient is opposite to the observed plasma drift.

  16. Electric force on plasma ions and the momentum of the ion-neutrals flow

    NASA Astrophysics Data System (ADS)

    Makrinich, G.; Fruchtman, A.; Zoler, D.; Boxman, R. L.

    2018-05-01

    The electric force on ions in plasma and the momentum flux carried by the mixed ion-neutral flow were measured and found to be equal. The experiment was performed in a direct-current gas discharge of cylindrical geometry with applied radial electric field and axial magnetic field. The unmagnetized plasma ions, neutralized by magnetized electrons, were accelerated radially outward transferring part of the gained momentum to neutrals. Measurements were taken for various argon gas flow rates between 13 and 100 Standard Cubic Centimeter per Minute, for a discharge current of 1.9 A and a magnetic field intensity of 136 G. The plasma density, electron temperature, and plasma potential were measured at various locations along the flow. These measurements were used to determine the local electric force on the ions. The total electric force on the plasma ions was then determined by integrating radially the local electric force. In parallel, the momentum flux of the mixed ion-neutral flow was determined by measuring the force exerted by the flow on a balance force meter (BFM). The maximal plasma density was between 6 × 1010 cm-3 and 5 × 1011 cm-3, the maximal electron temperature was between 8 eV and 25 eV, and the deduced maximal electric field was between 2200 V/m and 5800 V/m. The force exerted by the mixed ion-neutral flow on the BFM agreed with the total electric force on the plasma ions. This agreement showed that it is the electric force on the plasma ions that is the source of the momentum acquired by the mixed ion-neutral flow.

  17. Antiproton powered propulsion with magnetically confined plasma engines

    NASA Technical Reports Server (NTRS)

    Lapointe, Michael R.

    1989-01-01

    Matter-antimatter annihilation releases more energy per unit mass than any other method of energy production, making it an attractive energy source for spacecraft propulsion. In the magnetically confined plasma engine, antiproton beams are injected axially into a pulsed magnetic mirror system, where they annihilate with an initially neutral hydrogen gas. The resulting charged annihilation products transfer energy to the hydrogen propellant, which is then exhausted through one end of the pulsed mirror system to provide thrust. The calculated energy transfer efficiencies for a low number density (10(14)/cu cm) hydrogen propellant are insufficient to warrant operating the engine in this mode. Efficiencies are improved using moderate propellant number densities (10(16)/cu cm), but the energy transferred to the plasma in a realistic magnetic mirror system is generally limited to less than 2 percent of the initial proton-antiproton annihilation energy. The energy transfer efficiencies are highest for high number density (10(18)/cu cm) propellants, but plasma temperatures are reduced by excessive radiation losses. Low to moderate thrust over a wide range of specific impulse can be generated with moderate propellant number densities, while higher thrust but lower specific impulse may be generated using high propellant number densities. Significant mass will be required to shield the superconducting magnet coils from the high energy gamma radiation emitted by neutral pion decay. The mass of such a radiation shield may dominate the total engine mass, and could severely diminish the performance of antiproton powered engines which utilize magnetic confinement. The problem is compounded in the antiproton powered plasma engine, where lower energy plasma bremsstrahlung radiation may cause shield surface ablation and degradation.

  18. Paleolithic nutrition improves plasma lipid concentrations of hypercholesterolemic adults to a greater extent than traditional heart-healthy dietary recommendations.

    PubMed

    Pastore, Robert L; Brooks, Judith T; Carbone, John W

    2015-06-01

    Recent research suggests that traditional grain-based heart-healthy diet recommendations, which replace dietary saturated fat with carbohydrate and reduce total fat intake, may result in unfavorable plasma lipid ratios, with reduced high-density lipoprotein (HDL) and an elevation of low-density lipoprotein (LDL) and triacylglycerols (TG). The current study tested the hypothesis that a grain-free Paleolithic diet would induce weight loss and improve plasma total cholesterol, HDL, LDL, and TG concentrations in nondiabetic adults with hyperlipidemia to a greater extent than a grain-based heart-healthy diet, based on the recommendations of the American Heart Association. Twenty volunteers (10 male and 10 female) aged 40 to 62 years were selected based on diagnosis of hypercholesterolemia. Volunteers were not taking any cholesterol-lowering medications and adhered to a traditional heart-healthy diet for 4 months, followed by a Paleolithic diet for 4 months. Regression analysis was used to determine whether change in body weight contributed to observed changes in plasma lipid concentrations. Differences in dietary intakes and plasma lipid measures were assessed using repeated-measures analysis of variance. Four months of Paleolithic nutrition significantly lowered (P < .001) mean total cholesterol, LDL, and TG and increased (P < .001) HDL, independent of changes in body weight, relative to both baseline and the traditional heart-healthy diet. Paleolithic nutrition offers promising potential for nutritional management of hyperlipidemia in adults whose lipid profiles have not improved after following more traditional heart-healthy dietary recommendations. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. Plasma Component of Self-gravitating Disks and Relevant Magnetic Configurations

    NASA Astrophysics Data System (ADS)

    Bertin, G.; Coppi, B.

    2006-04-01

    Astrophysical disks in which the disk self-gravity is more important than the gravity force associated with the central object can have significant plasma components where appreciable toroidal current densities are produced. When the vertical confinement of the plasma rotating structures that can form is kept by the Lorentz force rather than by the vertical component of the gravity force, the disk self-gravity remains important only in the radial equilibrium condition, modifying the rotation curve from the commonly considered Keplerian rotation. The equilibrium equations that are solved involve the vertical and the horizontal components of the total momentum conservation equations, coupled with the lowest order form of the gravitational Poisson's equation. The resulting poloidal field configuration can be visualized as a sequence [1] of Field Reverse Configurations, in the radial direction, consisting of pairs of oppositely directed current channels. The plasma density thus acquires a significant radial modulation that may grow to the point where plasma rings can form [2]. [1] B. Coppi, Phys. Plasmas, 12, 057302 (2005) [2] B. Coppi and F. Rousseau, to be published in Astrophys. J. (April 2006)

  20. Effects of Chinese Dietary Pattern of Fat Content, n-6/n-3 Polyunsaturated Fatty Acid Ratio, and Cholesterol Content on Lipid Profile in Rats

    PubMed Central

    Zou, Xian-Guo; Huang, Yu-Hua; Xu, Tong-Cheng; Fan, Ya-Wei; Li, Jing

    2018-01-01

    This study aims to investigate the effect of Chinese diet pattern of fat content (30% or 36.06%), n-6/n-3 polyunsaturated fatty acid (PUFA) ratio (5 : 1 or 9 : 1), and cholesterol content (0.04 or 0.057 g/kg total diet) on lipid profile using a rat model. Results showed that rats' body weights (BWs) were controlled by the simultaneous intakes of cholesterol level of 0.04 g/kg total diet and n-6/n-3 ratio of 5 : 1. In addition, under high-fat diet, increased cholesterol feeding led to increased total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) levels and decreased triacylglycerols (TG) in rats' plasma. However, high density lipoprotein cholesterol (HDL-C) level and the ratios of HDL-C/LDL-C and HDL-C/TC in rats' plasma increased in response to simultaneous intakes of low n-6/n-3 ratio (5 : 1) and cholesterol (0.04 g/kg total diet) even under high-fat diet. Moreover, as the n-6/n-3 PUFA ratio in the diet decreased, the proportion of n-3 PUFAs increased in plasma, liver, and muscle and resulted in the decrease of n-6/n-3 PUFA ratio. PMID:29744358

  1. An association between the level of oxidative stress and the concentrations of NEFA and BHBA in the plasma of ketotic dairy cows.

    PubMed

    Li, Y; Ding, H Y; Wang, X C; Feng, S B; Li, X B; Wang, Z; Liu, G W; Li, X W

    2016-10-01

    The aim of this study was to evaluate the oxidative status in ketotic cows. We observed changes in the oxidative status and correlations between the oxidative and metabolic status in non-ketotic (n = 10), subclinical ketotic (n = 10) and ketotic cows (n = 10). Plasma samples were analysed by standard biochemical techniques and ELISA to determine traditional metabolic parameters: triglyceride (TG), phosphonium (P), calcium (Ca), aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), total protein (TP), albumin (ALB), immune globulin (Ig), total cholesterol (TC), high-density lipoprotein (HDL), very low-density lipoprotein (VLDL) and lactate dehydrogenase (LDH); energy metabolism indices: glucose, β-hydroxybutyrate (BHBA) and non-esterified fatty acids (NEFA); and indices of oxidative status: malondialdehyde (MDA), hydrogen peroxide (H2 O2 ), vitamin C, vitamin E, superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), catalase (CAT), xanthine oxidase (XOD) and total antioxidant capacity (TAOC). The results of this study showed that plasma glucose levels were lower in ketotic and subclinical ketotic cows than in non-ketotic cows; however, the plasma NEFA and BHBA concentrations were higher. In addition, significant decreases in TC, HDL and VLDL and significant increases in AST, ALT and LDH were observed in the plasma of the ketotic cows. The ketotic cows showed decreased plasma SOD, CAT, vitamin C and vitamin E, inhibited hydroxyl radical capacity and increased plasma H2 O2 and MDA. There were positive correlations between the plasma NEFA and ALT, AST, LDH and MDA and negative correlations between the plasma NEFA and TC, HDL, VLDL, SOD, vitamin C, vitamin E, 1542280 uric acid and inhibited hydroxyl radical capacity. In addition, there were positive correlations between BHBA concentrations and ALT, AST and LDH and negative correlations between plasma BHBA concentrations and TC, HDL, VLDL, vitamin E and inhibited hydroxyl radical capacity. Overall, ketotic dairy cows experience oxidative stress, which is presumably associated with hyperketonemia and higher NEFA. Journal of Animal Physiology and Animal Nutrition © 2016 Blackwell Verlag GmbH.

  2. Experimentally Determined Plasma Parameters in a 30 cm Ion Engine

    NASA Technical Reports Server (NTRS)

    Sengupta, Anita; Goebel, Dan; Fitzgerald, Dennis; Owens, Al; Tynan, George; Dorner, Russ

    2004-01-01

    Single planar Langmuir probes and fiber optic probes are used to concurrently measure the plasma properties and neutral density variation in a 30cm diameter ion engine discharge chamber, from the immediate vicinity of the keeper to the near grid plasma region. The fiber optic probe consists of a collimated optical fiber recessed into a double bore ceramic tube fitted with a stainless steel light-limiting window. The optical fiber probe is used to measure the emission intensity of excited neutral xenon for a small volume of plasma, at various radial and axial locations. The single Langmuir probes, are used to generate current-voltage characteristics at a total of 140 spatial locations inside the discharge chamber. Assuming a maxwellian distribution for the electron population, the Langmuir probe traces provide spatially resolved measurements of plasma potential, electron temperature, and plasma density. Data reduction for the NSTAR TH8 and TH15 throttle points indicates an electron temperature range of 1 to 7.9 eV and an electron density range of 4e10 to le13 cm(sup -3), throughout the discharge chamber, consistent with the results in the literature. Plasma potential estimates, computed from the first derivative of the probe characteristic, indicate potential from 0.5V to 11V above the discharge voltage along the thruster centerline. These values are believed to be excessively high due to the sampling of the primary electron population along the thruster centerline. Relative neutral density profiles are also obtained with a fiber optic probe sampling photon flux from the 823.1 nm excited to ground state transition. Plasma parameter measurements and neutral density profiles will be presented as a function of probe location and engine discharge conditions. A discussion of the measured electron energy distribution function will also be presented, with regards to variation from pure maxwellian. It has been found that there is a distinct primary population found along the thruster centerline, which causes estimates of electron temperature, electron density, and plasma potential, to err on the high side, due this energetic population. Computation of the energy distribution fimction of the plasma clearly indicates the presence of primaries, whose presence become less obvious with radial distance from the main discharge plume.

  3. Maternal plasma polyunsaturated fatty acid levels during pregnancy and childhood lipids and insulin levels

    PubMed Central

    Vidakovic, Aleksandra Jelena; Jaddoe, Vincent WV; Voortman, Trudy; Demmelmair, Hans; Koletzko, Berthold; Gaillard, Romy

    2017-01-01

    Background and Aims Maternal polyunsaturated fatty acid (PUFA) levels are associated with cord blood lipid and insulin levels. Not much is known about the influence of maternal PUFAs during pregnancy on long-term offspring lipid and insulin metabolism. We examined the associations of maternal plasma n-3 and n-6 PUFA levels during pregnancy with childhood lipids and insulin levels. Methods and Results In a population-based prospective cohort study among 3,230 mothers and their children, we measured maternal second trimester n-3 and n-6 PUFA plasma levels. At the median age of 6.0 years (95% range, 5.6-7.9), we measured childhood total-cholesterol, high-density lipoprotein (HDL)-cholesterol, low-density lipoprotein (LDL)-cholesterol, triglycerides, insulin and c-peptide levels. Higher maternal total n-3 PUFA levels, and specifically DHA levels, were associated with higher childhood total-cholesterol, HDL-cholesterol and insulin levels (p-values <0.05), but not with LDL-cholesterol and triglycerides. Maternal total n-6 PUFA levels were not associated with childhood outcomes, but higher levels of the individual n-6 PUFAs, EDA and DGLA were associated with a lower childhood HDL-cholesterol, and higher AA levels with higher childhood total-cholesterol and HDL-cholesterol levels (all p-values <0.05). A higher maternal n-6/n-3 PUFA ratio was only associated with lower childhood HDL-cholesterol and insulin levels (p-values <0.05). These associations were not explained by childhood body mass index. Conclusions Higher maternal total n-3 PUFAs and specifically DHA levels during pregnancy are associated with higher childhood total-cholesterol, HDL-cholesterol and insulin levels. Only individual maternal n-6 PUFAs, not total maternal n-6 PUFA levels, tended to be associated with childhood lipids and insulin levels. PMID:27919543

  4. Determining plasma parameters in cold, multi-species plasmas using Maxwell and Kappa distribution functions.

    NASA Astrophysics Data System (ADS)

    Jahn, J. M.; Denton, R. E.; Nose, M.; Bonnell, J. W.; Kurth, W. S.; Livadiotis, G.; Larsen, B.; Goldstein, J.

    2016-12-01

    Determining the total plasma density from ion data is essentially an impossible task for particle instruments. The lowest instrument energy threshold never includes the coldest particles (i.e., Emin> 0 eV), and any positive spacecraft charging—which is normal for a sunlit spacecraft—exacerbates the problem by shifting the detectable minimum energy to higher values. For ion data, traditionally field line resonance measurements of ULF waves in the magnetosphere have been used to determine the mass loading of magnetic field lines in this case. This approach delivers a reduced ion mass M that represents the mass ratio of all ions on a magnetic field line. For multi-species plasmas like the plasmasphere this bounds the problem, but it does not provide a unique solution. To at least estimate partial densities using particle instruments, one traditionally performs fits to the measured particle distribution functions under the assumption that the underlying particle distributions are Maxwellian. Uncertainties performing a fit aside, there is usually no possibility to detect a possible bi-Maxwellian distribution where one of the Maxwellians is very cold. The tail of such a distribution may fall completely below the low energy threshold of the measurement. In this paper we present a different approach to determining the fractional temperatures Ti and densities ni in a multi-species plasma. First, we describe and demonstrate an approach to determine Ti and ni that does not require fitting but relies more on the mathematical properties of the distribution functions. We apply our approach to Van Allen Probes measurements of the plasmaspheric H+, He+, and O+ distribution functions under the assumption that the particle distributions are Maxwellian. We compare our results to mass loading results from the Van Allen Probes field line resonance analyses (for composition) and to the total (electron) plasma density derived from the EFW and EMFISIS experiments. Then we expand our approach to allow for kappa distributions instead. While this introduces an additional degree of freedom and therefore requires fitting, our approach is still better constrained than the traditional Maxwell fitting and may hold the key to a better understanding of the true nature of plasmaspheric particle distributions.

  5. Turbulent fluctuations during pellet injection into a dipole confined plasma torus

    DOE PAGES

    Garnier, D. T.; Mauel, M. E.; Roberts, T. M.; ...

    2017-01-01

    Here, we report measurements of the turbulent evolution of the plasma density profile following the fast injection of lithium pellets into the Levitated Dipole Experiment (LDX) [Boxer et al., Nat. Phys. 6, 207 (2010)]. As the pellet passes through the plasma, it provides a significant internal particle source and allows investigation of density profile evolution, turbulent relaxation, and turbulent fluctuations. The total electron number within the dipole plasma torus increases by more than a factor of three, and the central density increases by more than a factor of five. During these large changes in density, the shape of the densitymore » profile is nearly “stationary” such that the gradient of the particle number within tubes of equal magnetic flux vanishes. In comparison to the usual case, when the particle source is neutral gas at the plasma edge, the internal source from the pellet causes the toroidal phase velocity of the fluctuations to reverse and changes the average particle flux at the plasma edge. An edge particle source creates an inward turbulent pinch, but an internal particle source increases the outward turbulent particle flux. Statistical properties of the turbulence are measured by multiple microwave interferometers and by an array of probes at the edge. The spatial structures of the largest amplitude modes have long radial and toroidal wavelengths. Estimates of the local and toroidally averaged turbulent particle flux show intermittency and a non-Gaussian probability distribution function. The measured fluctuations, both before and during pellet injection, have frequency and wave number dispersion consistent with theoretical expectations for interchange and entropy modes excited within a dipole plasma torus having warm electrons and cool ions.« less

  6. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Garnier, D. T.; Mauel, M. E.; Roberts, T. M.

    Here, we report measurements of the turbulent evolution of the plasma density profile following the fast injection of lithium pellets into the Levitated Dipole Experiment (LDX) [Boxer et al., Nat. Phys. 6, 207 (2010)]. As the pellet passes through the plasma, it provides a significant internal particle source and allows investigation of density profile evolution, turbulent relaxation, and turbulent fluctuations. The total electron number within the dipole plasma torus increases by more than a factor of three, and the central density increases by more than a factor of five. During these large changes in density, the shape of the densitymore » profile is nearly “stationary” such that the gradient of the particle number within tubes of equal magnetic flux vanishes. In comparison to the usual case, when the particle source is neutral gas at the plasma edge, the internal source from the pellet causes the toroidal phase velocity of the fluctuations to reverse and changes the average particle flux at the plasma edge. An edge particle source creates an inward turbulent pinch, but an internal particle source increases the outward turbulent particle flux. Statistical properties of the turbulence are measured by multiple microwave interferometers and by an array of probes at the edge. The spatial structures of the largest amplitude modes have long radial and toroidal wavelengths. Estimates of the local and toroidally averaged turbulent particle flux show intermittency and a non-Gaussian probability distribution function. The measured fluctuations, both before and during pellet injection, have frequency and wave number dispersion consistent with theoretical expectations for interchange and entropy modes excited within a dipole plasma torus having warm electrons and cool ions.« less

  7. Manganese oxide octahedral molecular sieve K-OMS-2 as catalyst in post plasma-catalysis for trichloroethylene degradation in humid air.

    PubMed

    Nguyen Dinh, M T; Giraudon, J-M; Vandenbroucke, A M; Morent, R; De Geyter, N; Lamonier, J-F

    2016-08-15

    The total oxidation of trichloroethylene (TCE) in air at low relative humidity (RH=10%) in the presence of CO2 (520ppmv) was investigated in function of energy density using an atmospheric pressure negative DC luminescent glow discharge combined with a cryptomelane catalyst positioned downstream of the plasma reactor at a temperature of 150°C. When using Non-Thermal Plasma (NTP) alone, it is found a low COx (x=1-2) yield in agreement with the detection of gaseous polychlorinated by-products in the outlet stream as well as ozone which is an harmful pollutant. Introduction of cryptomelane enhanced trichloroethylene removal, totally inhibited plasma ozone formation and increased significantly the COx yield. The improved performances of the hybrid system were mainly ascribed to the total destruction of plasma generated ozone on cryptomelane surface to produce active oxygen species. Consequently these active oxygen species greatly enhanced the abatement of the plasma non-reacted TCE and completely destroyed the hazardous plasma generated polychlorinated intermediates. The facile redox of Mn species associated with oxygen vacancies and mobility as well as the textural properties of the catalyst might also contribute as a whole to the efficiency of the process. Copyright © 2016 Elsevier B.V. All rights reserved.

  8. Ionization balance in Titan's nightside ionosphere

    NASA Astrophysics Data System (ADS)

    Vigren, E.; Galand, M.; Yelle, R. V.; Wellbrock, A.; Coates, A. J.; Snowden, D.; Cui, J.; Lavvas, P.; Edberg, N. J. T.; Shebanits, O.; Wahlund, J.-E.; Vuitton, V.; Mandt, K.

    2015-03-01

    Based on a multi-instrumental Cassini dataset we make model versus observation comparisons of plasma number densities, nP = (nenI)1/2 (ne and nI being the electron number density and total positive ion number density, respectively) and short-lived ion number densities (N+, CH2+, CH3+, CH4+) in the southern hemisphere of Titan's nightside ionosphere over altitudes ranging from 1100 and 1200 km and from 1100 to 1350 km, respectively. The nP model assumes photochemical equilibrium, ion-electron pair production driven by magnetospheric electron precipitation and dissociative recombination as the principal plasma neutralization process. The model to derive short-lived-ion number densities assumes photochemical equilibrium for the short-lived ions, primary ion production by electron-impact ionization of N2 and CH4 and removal of the short-lived ions through reactions with CH4. It is shown that the models reasonably reproduce the observations, both with regards to nP and the number densities of the short-lived ions. This is contrasted by the difficulties in accurately reproducing ion and electron number densities in Titan's sunlit ionosphere.

  9. Resonance in fast-wave amplitude in the periphery of cylindrical plasmas and application to edge losses of wave heating power in tokamaks

    DOE PAGES

    Perkins, R. J.; Hosea, J. C.; Bertelli, N.; ...

    2016-07-01

    Heating magnetically confined plasmas using waves in the ion-cyclotron range of frequencies typically requires coupling these waves over a steep density gradient. Furthermore, this process has produced an unexpected and deleterious phenomenon on the National Spherical Torus eXperiment (NSTX): a prompt loss of wave power along magnetic field lines in front of the antenna to the divertor. Understanding this loss may be key to achieving effective heating and expanding the operational space of NSTX-Upgrade. Here, we propose that a new type of mode, which conducts a significant fraction of the total wave power in the low-density peripheral plasma, is drivingmore » these losses. We demonstrate the existence of such modes, which are distinct from surface modes and coaxial modes, in a cylindrical cold-plasma model when a half wavelength structure fits into the region outside the core plasma. The latter condition generalizes the previous hypothesis regarding the occurence of the edge losses and may explain why full-wave simulations predict these losses in some cases but not others. If valid, this condition implies that outer gap control is a potential strategy for mitigating the losses in NSTX-Upgrade in addition to raising the magnetic field or influencing the edge density.« less

  10. Comparison of hybrid and baseline ELMy H-mode confinement in JET with the carbon wall

    NASA Astrophysics Data System (ADS)

    Beurskens, M. N. A.; Frassinetti, L.; Challis, C.; Osborne, T.; Snyder, P. B.; Alper, B.; Angioni, C.; Bourdelle, C.; Buratti, P.; Crisanti, F.; Giovannozzi, E.; Giroud, C.; Groebner, R.; Hobirk, J.; Jenkins, I.; Joffrin, E.; Leyland, M. J.; Lomas, P.; Mantica, P.; McDonald, D.; Nunes, I.; Rimini, F.; Saarelma, S.; Voitsekhovitch, I.; de Vries, P.; Zarzoso, D.; Contributors, JET-EFDA

    2013-01-01

    The confinement in JET baseline type I ELMy H-mode plasmas is compared to that in so-called hybrid H-modes in a database study of 112 plasmas in JET with the carbon fibre composite (CFC) wall. The baseline plasmas typically have βN ˜ 1.5-2, H98 ˜ 1, whereas the hybrid plasmas have βN ˜ 2.5-3, H98 < 1.5. The database study contains both low- (δ ˜ 0.2-0.25) and high-triangularity (δ ˜ 0.4) hybrid and baseline H-mode plasmas from the last JET operational campaigns in the CFC wall from the period 2008-2009. Based on a detailed confinement study of the global as well as the pedestal and core confinement, there is no evidence that the hybrid and baseline plasmas form separate confinement groups; it emerges that the transition between the two scenarios is of a gradual kind rather than demonstrating a bifurcation in the confinement. The elevated confinement enhancement factor H98 in the hybrid plasmas may possibly be explained by the density dependence in the τ98 scaling as n0.41 and the fact that the hybrid plasmas operate at low plasma density compared to the baseline ELMy H-mode plasmas. A separate regression on the confinement data in this study shows a reduction in the density dependence as n0.09±0.08. Furthermore, inclusion of the plasma toroidal rotation in the confinement regression provides a scaling with the toroidal Alfvén Mach number as Mach_A^{0.41+/- 0.07} and again a reduced density dependence as n0.15±0.08. The differences in pedestal confinement can be explained on the basis of linear MHD stability through a coupling of the total and pedestal poloidal pressure and the pedestal performance can be improved through plasma shaping as well as high β operation. This has been confirmed in a comparison with the EPED1 predictive pedestal code which shows a good agreement between the predicted and measured pedestal pressure within 20-30% for a wide range of βN ˜ 1.5-3.5. The core profiles show a strong degree of pressure profile consistency. No beneficial effect of core density peaking on confinement could be identified for the majority of the plasmas presented here as the density peaking is compensated by a temperature de-peaking resulting in no or only a weak variation in the pressure peaking. The core confinement could only be optimized in case the ions and electrons are decoupled, in which case the ion temperature profile peaking can be enhanced, which benefits confinement. In this study, the latter has only been achieved in the low-triangularity hybrid plasmas, and can be attributed to low-density operation. Plasma rotation has been found to reduce core profile stiffness, and can explain an increase in profile peaking at small radius ρtor = 0.3.

  11. [Cholesterol of the high-density lipoprotein subclasses in the native inhabitants of the Chukchi National Autonomous Okrug].

    PubMed

    Polesskiĭ, V A; Chepurnenko, N V; Koshechkin, V A; Morozov, V V; Gerasimova, E N

    1980-12-01

    The authors studied the content of total cholesterol (Ch), triglycerides (TG), CS of high density lipoprotein (HDL2 and HDL3) subclasses and testosterone in blood plasma of 30-59-year-old males, natives or newcomers of Chukotsk, and compared the results with the corresponding values determined in the male population of Moscow. It was established that the mean HDL Ch concentration in blood plasma was higher and the content of TG and to a lesser degree that of total CS, was lower in the Chukchi males than in the male Moscow population and in the newcomers who were examined. It was also shown that in hypo- and hyper-alphalipoproteinemia in all groups examined, the content of HDL2 Ch changed for the most part (decreased or increased, respectively) while the level of HDL3 Ch remained relatively stable.

  12. Betaine and arginine supplementation of low protein diets improves plasma lipids but does not affect hepatic fatty acid composition and related gene expression profiling in pigs.

    PubMed

    Madeira, Marta S; Rolo, Eva A; Lopes, Paula A; Ramos, Denis A; Alfaia, Cristina M; Pires, Virgínia Mr; Martins, Susana V; Pinto, Rui Ma; Prates, José Am

    2018-01-01

    The individual and combined effects of betaine and arginine supplemented to reduced protein diets were investigated on plasma metabolites, hepatic fatty acid composition and mRNA levels of lipid-sensitive factors in commercial pigs. Betaine has previously been shown to reduce carcass fat deposition and arginine improves meat quality of finishing pigs. Forty male crossbred pigs were randomly assigned to one of five diets (n = 8): 160 g kg -1 of crude protein (NPD), 130 g kg -1 of crude protein (RPD), RPD with 3.3 g kg -1 of betaine, RPD with 15 g kg -1 of arginine, and RPD with 3.3 g kg -1 of betaine and 15 g kg -1 of arginine. The restriction of dietary protein increased total lipids (P < 0.001), total cholesterol (P < 0.001), high-density lipoprotein-cholesterol (P < 0.001) and low-density lipoprotein cholesterol (P < 0.001). Betaine and arginine, individually or combined, reduced the majority of plasma lipids (P < 0.05) without affecting total fatty acids in the liver and the overall gene expression pattern. These findings suggest a positive effect of betaine and arginine, singly or combined, by reversing plasma lipids increase promoted by dietary protein restriction. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  13. Design of novel dual-port tapered waveguide plasma apparatus by numerical analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, D.; Zhou, R.; Yang, X. Q., E-mail: yyxxqq-mail@163.com

    Microwave plasma apparatus is often of particular interest due to their superiority of low cost, electrode contamination free, and suitability for industrial production. However, there exist problems of unstable plasma and low electron density in conventional waveguide apparatus based on single port, due to low strength and non-uniformity of microwave field. This study proposes a novel dual-port tapered waveguide plasma apparatus based on power-combining technique, to improve the strength and uniformity of microwave field for the applications of plasma. A 3D model of microwave-induced plasma (field frequency 2.45 GHz) in argon at atmospheric pressure is presented. On the condition thatmore » the total input power is 500 W, simulations indicate that coherent power-combining will maximize the electric-field strength to 3.32 × 10{sup 5 }V/m and improve the uniformity of distributed microwave field, which raised 36.7% and 47.2%, respectively, compared to conventional waveguide apparatus of single port. To study the optimum conditions for industrial application, a 2D argon fluid model based on above structure is presented. It demonstrates that relatively uniform and high-density plasma is obtained at an argon flow rate of 200 ml/min. The contrastive result of electric-field distribution, electron density, and gas temperature is also valid and clearly proves the superiority of coherent power-combining to conventional technique in flow field.« less

  14. A titanium hydride gun for plasma injection into the T2-reversed field pinch device

    NASA Astrophysics Data System (ADS)

    Voronin, A. V.; Hellblom, K. G.

    1999-02-01

    A study of a plasma gun (modified Bostic type) with titanium hydride electrodes has been carried out. The total number of released hydrogen atoms was in the range 1016-1018 and the maximum plasma flow velocity was 2.5×105 m s-1. The ion density near the gun edge reached 1.8×1020 m-3 and the electron temperature was around 40 eV as estimated from probe measurements. No species other than hydrogen or titanium were seen in the plasma line radiation. The plasma injector was successfully used for gas pre-ionization in the Extrap T2 reversed-field pinch device (ohmic heating toroidal experiment (OHTE)).

  15. Developing the science and technology for the Material Plasma Exposure eXperiment

    DOE PAGES

    Rapp, J.; Biewer, T. M.; Bigelow, T. S.; ...

    2017-07-27

    Linear plasma generators are cost effective facilities to simulate divertor plasma conditions of present and future fusion reactors. They are used to address important R&D gaps in the science of plasma material interactions and towards viable plasma facing components for fusion reactors. Next generation plasma generators have to be able to access the plasma conditions expected on the divertor targets in ITER and future devices. The steady-state linear plasma device MPEX will address this regime with electron temperatures of 1–10 eV and electron densities ofmore » $$10^{21}{\\text{}}\\!-\\!10^{20}$$ $${\\rm m}^{-3}$$. The resulting heat fluxes are about 10 MW $${\\rm m}^{-2}$$ . MPEX is designed to deliver those plasma conditions with a novel Radio Frequency plasma source able to produce high density plasmas and heat electron and ions separately with electron Bernstein wave (EBW) heating and ion cyclotron resonance heating with a total installed power of 800 kW. The linear device Proto-MPEX, forerunner of MPEX consisting of 12 water-cooled copper coils, has been operational since May 2014. Its helicon antenna (100 kW, 13.56 MHz) and EC heating systems (200 kW, 28 GHz) have been commissioned and 14 MW $${\\rm m}^{-2}$$ was delivered on target. Furthermore, electron temperatures of about 20 eV have been achieved in combined helicon and ECH heating schemes at low electron densities. Overdense heating with EBW was achieved at low heating powers. The operational space of the density production by the helicon antenna was pushed up to $$1.1 \\times 10^{20}$$ $${\\rm m}^{-3}$$ at high magnetic fields of 1.0 T at the target. Finally, the experimental results from Proto-MPEX will be used for code validation to enable predictions of the source and heating performance for MPEX. MPEX, in its last phase, will be capable to expose neutron-irradiated samples. In this concept, targets will be irradiated in ORNL's High Flux Isotope Reactor and then subsequently exposed to fusion reactor relevant plasmas in MPEX.« less

  16. Developing the science and technology for the Material Plasma Exposure eXperiment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rapp, J.; Biewer, T. M.; Bigelow, T. S.

    Linear plasma generators are cost effective facilities to simulate divertor plasma conditions of present and future fusion reactors. They are used to address important R&D gaps in the science of plasma material interactions and towards viable plasma facing components for fusion reactors. Next generation plasma generators have to be able to access the plasma conditions expected on the divertor targets in ITER and future devices. The steady-state linear plasma device MPEX will address this regime with electron temperatures of 1–10 eV and electron densities ofmore » $$10^{21}{\\text{}}\\!-\\!10^{20}$$ $${\\rm m}^{-3}$$. The resulting heat fluxes are about 10 MW $${\\rm m}^{-2}$$ . MPEX is designed to deliver those plasma conditions with a novel Radio Frequency plasma source able to produce high density plasmas and heat electron and ions separately with electron Bernstein wave (EBW) heating and ion cyclotron resonance heating with a total installed power of 800 kW. The linear device Proto-MPEX, forerunner of MPEX consisting of 12 water-cooled copper coils, has been operational since May 2014. Its helicon antenna (100 kW, 13.56 MHz) and EC heating systems (200 kW, 28 GHz) have been commissioned and 14 MW $${\\rm m}^{-2}$$ was delivered on target. Furthermore, electron temperatures of about 20 eV have been achieved in combined helicon and ECH heating schemes at low electron densities. Overdense heating with EBW was achieved at low heating powers. The operational space of the density production by the helicon antenna was pushed up to $$1.1 \\times 10^{20}$$ $${\\rm m}^{-3}$$ at high magnetic fields of 1.0 T at the target. Finally, the experimental results from Proto-MPEX will be used for code validation to enable predictions of the source and heating performance for MPEX. MPEX, in its last phase, will be capable to expose neutron-irradiated samples. In this concept, targets will be irradiated in ORNL's High Flux Isotope Reactor and then subsequently exposed to fusion reactor relevant plasmas in MPEX.« less

  17. X-ray source characterization of aluminum X-pinch plasmas driven by the 0. 5 TW LION accelerator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Qi, N.; Hammer, D.A.; Kalantar, D.H.

    1989-12-01

    Recent experiments at Cornell have been performed to investigate X-pinch plasmas as intense x-ray sources which might be used to pump resonant photoexcitation lasers. Crossed Al wires have been driven by up to 600 kA current for 40 ns. High density bright spots are observed at the crossing point(s). Various diagnostics were used to characterize the X-pinch plasmas as a function of initial mass loading for several specific wire configurations. The optimum mass loading for different ionization stages of Al, and the total x-ray energy yields, which are on the order of hundreds of Joules, were examined. Estimates of plasmamore » density, {similar to}10{sup 20} cm{sup {minus}3}, and temperature, about 400 eV, were obtained.« less

  18. Diagnostic Suite for HyperV Coaxial Plasma Gun Development for the PLX- α Project

    NASA Astrophysics Data System (ADS)

    Case, Andrew; Brockington, Sam; Witherspoon, F. Douglas

    2015-11-01

    We present the diagnostic suite to be used during development of the coaxial guns HyperV will deliver to LANL in support of the ARPA-E Accelerating Low-Cost Plasma Heating And Assembly (ALPHA) program. For plasma jet diagnostics this includes fast photodiodes for velocimetry, a ballistic pendulum for measuring total plasmoid momentum, interferometry for line integrated plasma density, deflectometry for line integrated perpendicular density gradient measurements, and spectroscopy, both time resolved high resolution spectroscopy using a novel detector developed by HyperV and time integrated survey spectroscopy, for measurements of velocity and temperature as well as impurities. In addition, we plan to use fast pressure probes for stagnation pressure, a Faraday cup for density, fast imaging for plume geometry and time integrated imaging for overall light emission. A novel low resolution long record length camera developed by HyperV will also be used for plume diagnostics. For diagnostics of gun operation, we will use Rogowski coils to measure current, voltage dividers for voltages, B-dot probes for magnetic field, and time resolved fast photodiodes to measure plasmoid velocity inside the accelerator. This work supported by the ARPA-E ALPHA program.

  19. SKI-II--a sphingosine kinase 1 inhibitor--exacerbates atherosclerosis in low-density lipoprotein receptor-deficient (LDL-R-/-) mice on high cholesterol diet.

    PubMed

    Potì, Francesco; Ceglarek, Uta; Burkhardt, Ralph; Simoni, Manuela; Nofer, Jerzy-Roch

    2015-05-01

    Sphingosine 1-phosphate (S1P) is a lysosphingolipid associated with high-density lipoproteins (HDL) that contributes to their anti-atherogenic potential. We investigated whether a reduction in S1P plasma levels affects atherosclerosis in low-density lipoprotein receptor deficient (LDL-R-/-) mice. LDL-R-/- mice on Western diet containing low (0.25% w/w) or high (1.25% w/w) cholesterol were treated for 16 weeks with SKI-II, a sphingosine kinase 1 inhibitor that significantly reduced plasma S1P levels. SKI-II treatment increased atherosclerotic lesions in the thoracic aorta in mice on high but not low cholesterol diet. This compound did not affect body weight, blood cell counts and plasma total and HDL cholesterol, but decreased triglycerides. In addition, mice on high cholesterol diet receiving SKI-II showed elevated levels of tumor necrosis factor-α and endothelial adhesion molecules (sICAM-1, sVCAM-1). Prolonged lowering of plasma S1P produces pro-atherogenic effects in LDL-R-/- mice that are evident under condition of pronounced hypercholesterolemia. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  20. Modulating efficacy of Rebaudioside A, a diterpenoid on antioxidant and circulatory lipids in experimental diabetic rats.

    PubMed

    Saravanan, Ramalingam; Ramachandran, Vinayagam

    2013-09-01

    The present study was to evaluate the protective effects of Rebaudioside A (Reb A) on antioxidant status and lipid profile in streptozotocin (STZ)-induced diabetic rats. Diabetes was induced in Wistar rats by a single intraperitoneal administration of STZ (40mg/kg b.w). Diabetic rats showed significantly increased levels of plasma glucose, thiobarbituric acid reactive substances, hydroperoxides and decreased levels of insulin. The activity of enzymatic antioxidants (superoxide dismutase, catalase and glutathione peroxidase) and the levels of non enzymatic antioxidants (vitamin C, vitamin E and reduced glutathione) were decreased in diabetic rats. The levels of total cholesterol (TC), triglycerides (TGs), free fatty acids (FFAs), phospholipids (PLs), low density lipoproteins (LDL-cholesterol) and very low-density lipoproteins (VLDL-cholesterol) in the plasma significantly increased, while plasma high-density lipoproteins (HDL-cholesterol) were significantly decreased in diabetic rats. Oral administration of Reb A (200mg/kg b.w) brought back plasma glucose, insulin, lipid peroxidation products, enzymatic, non-enzymatic antioxidants and lipid profile levels to near normal. The results of the present investigation suggests that Reb A, a natural sweetener exhibits antilipid peroxidative, antihyperlipidemic and antioxidant properties. Copyright © 2013 Elsevier B.V. All rights reserved.

  1. Measurements of the ambient photoelectron spectrum from Atmosphere Explorer. I - AE-E measurements below 300 km during solar minimum conditions. II - AE-E measurements from 300 to 1000 km during solar minimum conditions

    NASA Technical Reports Server (NTRS)

    Lee, J. S.; Doering, J. P.; Potemra, T. A.; Brace, L. H.

    1980-01-01

    A study is presented of the ambient photoelectron spectrum below 300 km which includes 500 AE-E orbits observed from Dec. 13, 1975 to Feb. 24, 1976. The daytime photoelectron spectrum from 1 to 100 eV was illustrated by several spectra; high resolution 10-32 eV spectra show the widths of the photoelectron lines and the variation of the linewidth and intensity with altitude. The photoelectron flux below 300 km is constant over a period of several months; the photoelectron lines between 20 and 30 eV are very sharp when the total plasma density is low, but broaden at high altitudes as the plasma density builds up during the day. The photo-electron flux above 300 km had an intensity and energy spectrum characteristic of the 250-300 km region only in the presence of low plasma density at the satellite altitude. The flux at high altitudes was extremely variable 3 h after sunrise as a result of attenuation and energy loss to thermal plasma along the path of escaping electrons.

  2. Intermittent electron density and temperature fluctuations and associated fluxes in the Alcator C-Mod scrape-off layer

    NASA Astrophysics Data System (ADS)

    Kube, R.; Garcia, O. E.; Theodorsen, A.; Brunner, D.; Kuang, A. Q.; LaBombard, B.; Terry, J. L.

    2018-06-01

    The Alcator C-Mod mirror Langmuir probe system has been used to sample data time series of fluctuating plasma parameters in the outboard mid-plane far scrape-off layer. We present a statistical analysis of one second long time series of electron density, temperature, radial electric drift velocity and the corresponding particle and electron heat fluxes. These are sampled during stationary plasma conditions in an ohmically heated, lower single null diverted discharge. The electron density and temperature are strongly correlated and feature fluctuation statistics similar to the ion saturation current. Both electron density and temperature time series are dominated by intermittent, large-amplitude burst with an exponential distribution of both burst amplitudes and waiting times between them. The characteristic time scale of the large-amplitude bursts is approximately 15 μ {{s}}. Large-amplitude velocity fluctuations feature a slightly faster characteristic time scale and appear at a faster rate than electron density and temperature fluctuations. Describing these time series as a superposition of uncorrelated exponential pulses, we find that probability distribution functions, power spectral densities as well as auto-correlation functions of the data time series agree well with predictions from the stochastic model. The electron particle and heat fluxes present large-amplitude fluctuations. For this low-density plasma, the radial electron heat flux is dominated by convection, that is, correlations of fluctuations in the electron density and radial velocity. Hot and dense blobs contribute only a minute fraction of the total fluctuation driven heat flux.

  3. The Influence of Current Density and Magnetic Field Topography in Optimizing the Performance, Divergence, and Plasma Oscillations of High Specific Impulse Hall Thrusters

    NASA Technical Reports Server (NTRS)

    Hofer, Richard R.; Jankovsky, Robert S.

    2003-01-01

    Recent studies of xenon Hall thrusters have shown peak efficiencies at specific impulses of less than 3000 s. This was a consequence of modern Hall thruster magnetic field topographies, which have been optimized for 300 V discharges. On-going research at the NASA Glenn Research Center is investigating this behavior and methods to enhance thruster performance. To conduct these studies, a laboratory model Hall thruster that uses a pair of trim coils to tailor the magnetic field topography for high specific impulse operation has been developed. The thruster-the NASA-173Mv2 was tested to determine how current density and magnetic field topography affect performance, divergence, and plasma oscillations at voltages up to 1000 V. Test results showed there was a minimum current density and optimum magnetic field topography at which efficiency monotonically increased with voltage. At 1000 V, 10 milligrams per second the total specific impulse was 3390 s and the total efficiency was 60.8%. Plume divergence decreased at 400-1000 V, but increased at 300-400 V as the result of plasma oscillations. The dominant oscillation frequency steadily increased with voltage, from 14.5 kHz at 300 V, to 22 kHz at 1000 V. An additional oscillatory mode in the 80-90 kHz frequency range began to appear above 500 V. The use of trim coils to modify the magnetic field improved performance while decreasing plume divergence and the frequency and magnitude of plasma oscillations.

  4. Non-thermal plasma modified growth and differentiation process of Capsicum annuum PP805 Godiva in in vitro conditions

    NASA Astrophysics Data System (ADS)

    Safari, Nasrin; Iranbakhsh, Alireza; Ardebili, Zahra Oraghi

    2017-05-01

    With the aim of evaluating the possible impacts of cold plasma on the structure and growth pattern of Capsicum annuum, the current study was carried out. The seeds were exposed to an argon-derived plasma (0.84 W cm-2 surface power densities) for 0, 1 or 2 minutes. Plasma-treated seeds were grown in the Murashige and Skoog (MS) medium or MS medium supplemented with BA and IAA. The presence of purple stems was recorded in plasma-treated plants grown in the medium supplemented with hormones. The recorded morphological differences were dependent on the exposure time of plasma treatments and/or the presence of hormones in the culture media. Plasma treatment of 1 minute had an improving effect on the shoot and root lengths as well as total leaf area, whereas plasma treatment of 2 minutes had an adverse effect. In contrast to the 1 minute treatment, plasma treatment of 2 minutes significantly impaired growth and hence reduced the total biomass. Alterations in stem diameter and differences in tissue patterns (especially in the vascular system) occurred, and were mainly dependent on the plasma exposure time and/or the presence of hormones. This is a first report on the effects of cold plasma on plant growth in in vitro conditions.

  5. Plasma density irregularities and Total Electron Content gradients over Europe

    NASA Astrophysics Data System (ADS)

    Zakharenkova, I.; Kotulak, K.; Cherniak, I.; Krankowski, A.; Froń, A.

    2017-12-01

    Perturbations of the ionospheric plasma density are crucial from the scientific and application points of view, as they can severe affect radio signals used in the Global Navigation Satellite Systems (GNSS) and low frequency radio astronomy. For several decades the ionospheric irregularities have been extensively studied by different techniques, including ground-based GNSS observations. Spatial distribution of ionospheric disturbances can be specified by horizontal gradients of the ionospheric density (total electron content, TEC). Another, widely used tool in irregularities monitoring is the rate of TEC index (ROTI). Recently, the Northern Hemisphere ROTI product has been implemented to the International GNSS Service (IGS) and available for community. In this study, we present climatology of the spatial TEC gradients occurred over European region at high to middle latitudes. We developed the TEC gradient maps based on the high-resolution (0.5 degree in latitude and longitude) regional TEC maps covering Europe. The obtained climatological characteristics of the spatial TEC gradients are superimposed and analyzed with the global and regional ROTI product in order to reveal development of highly intense plasma irregularities occurred at high and middle latitudes. During geomagnetic storm the complex of physical processes at auroal zone leads to development of intnse ionospheric irregularities and travelling ionospheric disturbances (TIDs). We presents results of the geomagnetic storm analysis including the 2013 and 2015 St. Patrick's Day geomagnetic storms.

  6. Entire plasmas can be restructured when electrons are emitted from the boundaries

    DOE PAGES

    Campanell, M. D.

    2015-04-14

    It is well known that electron emission can restructure the thin sheaths at plasma-facing surfaces. But conventional models assume that the plasma's structure negligibly changes (the “presheath” is still thought to be governed by ion acceleration to the Bohm speed). Here, it is shown by theory and simulation that the presheath can take a fundamentally different structure where the emitted electrons entering the quasineutral region cause numerous changes. As a result, gradients of total plasma density, ion and electron pressures, and electric potential throughout the “inverted” presheath can carry different magnitudes, and opposite signs, from Bohm presheaths.

  7. Perfluoroalkyl substances and lipid concentrations in plasma during pregnancy among women in the Norwegian Mother and Child Cohort Study

    PubMed Central

    Starling, Anne P.; Engel, Stephanie M.; Whitworth, Kristina W.; Richardson, David B.; Stuebe, Alison M.; Daniels, Julie L.; Haug, Line Småstuen; Eggesbø, Merete; Becher, Georg; Sabaredzovic, Azemira; Thomsen, Cathrine; Wilson, Ralph E.; Travlos, Gregory S.; Hoppin, Jane A.; Baird, Donna D.; Longnecker, Matthew P.

    2013-01-01

    Background Perfluoroalkyl substances (PFASs) are widespread and persistent environmental pollutants. Previous studies, primarily among non-pregnant individuals, suggest positive associations between PFAS levels and certain blood lipids. If there is a causal link between PFAS concentrations and elevated lipids during pregnancy, this may suggest a mechanism by which PFAS exposure leads to certain adverse pregnancy outcomes, including preeclampsia. Methods This cross-sectional analysis included 891 pregnant women enrolled in the Norwegian Mother and Child (MoBa) Cohort Study in 2003–2004. Non-fasting plasma samples were obtained at mid-pregnancy and analyzed for nineteen PFASs. Total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein cholesterol, and triglycerides were measured in plasma. Linear regression was used to quantify associations between each PFAS exposure and each lipid outcome. A multiple PFAS model was also fitted. Results Seven PFASs were quantifiable in >50% of samples. Perfluorooctane sulfonate (PFOS) concentration was associated with total cholesterol, which increased 4.2 mg/dL per interquartile shift (95% CI=0.8, 7.7) in adjusted models. Five of the seven PFASs studied were positively associated with HDL cholesterol, and all seven had elevated HDL associated with the highest quartile of exposure. Perfluoroundecanoic acid showed the strongest association with HDL: HDL increased 3.7 mg/dL per interquartile shift (95% CI=2.5, 4.9). Conclusion Plasma concentrations of PFASs were positively associated with HDL cholesterol, and PFOS was positively associated with total cholesterol in this sample of pregnant Norwegian women. While elevated HDL is not an adverse outcome per se, elevated total cholesterol associated with PFASs during pregnancy could be of concern if causal. PMID:24189199

  8. Aronia berry polyphenol consumption reduces plasma total and low-density lipoprotein cholesterol in former smokers without lowering biomarkers of inflammation and oxidative stress: a randomized controlled trial.

    PubMed

    Xie, Liyang; Vance, Terrence; Kim, Bohkyung; Lee, Sang Gil; Caceres, Christian; Wang, Ying; Hubert, Patrice A; Lee, Ji-Young; Chun, Ock K; Bolling, Bradley W

    2017-01-01

    Former smokers are at increased risk for cardiovascular disease. We hypothesized that dietary aronia polyphenols would reduce biomarkers of cardiovascular disease risk, inflammation, and oxidative stress in former smokers. We also determined the extent these effects were associated with polyphenol bioavailability. A 12-week, randomized, placebo-controlled trial was conducted in 49 healthy adult former smokers (n = 24/placebo, n = 25/aronia) to evaluate if daily consumption of 500 mg aronia extract modulated plasma lipids, blood pressure, biomarkers of inflammation and oxidative stress, and lipid transport genes of peripheral blood mononuclear cells. The primary outcome was change in low-density lipoprotein cholesterol (LDL-C) from baseline, and multivariate correlation analysis was performed to determine if changes in lipids were associated with urinary polyphenol excretion. Aronia consumption reduced fasting plasma total cholesterol by 8% (P = .0140), LDL-C by 11% (P = .0285), and LDL receptor protein in peripheral blood mononuclear cells (P = .0036) at 12 weeks compared with the placebo group. Positive changes in the urinary polyphenol metabolites peonidin-3-O-galactoside, 3-(4-hydroxyphenyl) propionic acid, and unmetabolized anthocyanin cyanidin-3-O-galactoside were associated with lower plasma total cholesterol and LDL-C in the aronia group. Aronia consumption did not change blood pressure or biomarkers of inflammation and oxidative stress. Aronia polyphenols reduced total and LDL-C in former smokers but did not improve biomarkers of oxidative stress and chronic inflammation. The cholesterol-lowering activity of aronia extract was most closely associated with urinary levels of cyanidin-3-O-galactoside and peonidin-3-O-galactoside, its methylated metabolite. This trial was registered at ClinicalTrials.gov as NCT01541826. Copyright © 2016 Elsevier Inc. All rights reserved.

  9. Perfluoroalkyl substances and lipid concentrations in plasma during pregnancy among women in the Norwegian Mother and Child Cohort Study.

    PubMed

    Starling, Anne P; Engel, Stephanie M; Whitworth, Kristina W; Richardson, David B; Stuebe, Alison M; Daniels, Julie L; Haug, Line Småstuen; Eggesbø, Merete; Becher, Georg; Sabaredzovic, Azemira; Thomsen, Cathrine; Wilson, Ralph E; Travlos, Gregory S; Hoppin, Jane A; Baird, Donna D; Longnecker, Matthew P

    2014-01-01

    Perfluoroalkyl substances (PFASs) are widespread and persistent environmental pollutants. Previous studies, primarily among non-pregnant individuals, suggest positive associations between PFAS levels and certain blood lipids. If there is a causal link between PFAS concentrations and elevated lipids during pregnancy, this may suggest a mechanism by which PFAS exposure leads to certain adverse pregnancy outcomes, including preeclampsia. This cross-sectional analysis included 891 pregnant women enrolled in the Norwegian Mother and Child (MoBa) Cohort Study in 2003-2004. Non-fasting plasma samples were obtained at mid-pregnancy and analyzed for nineteen PFASs. Total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein cholesterol, and triglycerides were measured in plasma. Linear regression was used to quantify associations between each PFAS exposure and each lipid outcome. A multiple PFAS model was also fitted. Seven PFASs were quantifiable in >50% of samples. Perfluorooctane sulfonate (PFOS) concentration was associated with total cholesterol, which increased 4.2mg/dL per inter-quartile shift (95% CI=0.8, 7.7) in adjusted models. Five of the seven PFASs studied were positively associated with HDL cholesterol, and all seven had elevated HDL associated with the highest quartile of exposure. Perfluoroundecanoic acid showed the strongest association with HDL: HDL increased 3.7 mg/dL per inter-quartile shift (95% CI=2.5, 4.9). Plasma concentrations of PFASs were positively associated with HDL cholesterol, and PFOS was positively associated with total cholesterol in this sample of pregnant Norwegian women. While elevated HDL is not an adverse outcome per se, elevated total cholesterol associated with PFASs during pregnancy could be of concern if causal. © 2013.

  10. Characteristics of the Dust-Plasma Interaction Near Enceladus' South Pole

    NASA Technical Reports Server (NTRS)

    Shafiq, Muhammad; Wahlund, J.-E.; Morooka, M. W; Kurth, W. S.; Farrell, W. M.

    2010-01-01

    We present RPWS Langmuir probe data from the third Enceladus flyby (E3) showing (he presence of dusty plasma near Enceladus' South Pole. There is a sharp rise in both the electron and ion number densities when the spacecraft traverses through Enceladus plume. The ion density near Enceladus is found to increase abruptly from about 10(exp 2) cm (exp -3) before the closest approach to 10(exp 5) cm (exp -3) just 30 s after the closest approach, an amount two orders of magnitude higher than the electron density. Assuming that the inconsistency between the electron and ion number densities is due to the presence of dust particles that are collecting the missing electron charges, we present dusty plasma characteristics down to sub-micron particle sizes. By assuming a differential dust number density for a range in dust sizes and by making use of Langmuir probe data, the dust densities for certain lower limits in dust size distribution were estimated. In order to achieve the dust densities of micrometer and larger sized grains comparable to the ones reported in the literature. we show that the power law size distribution must hold down to at least 0.03 micron such that the total differential number density is dominated by the smallest sub-micron sized grains. The total dust number density in Enceladus' plume is of the order of l0(exp 2) cm(exp -3) reducing to 1 cm(exp -3) in the E- ring. The dust density for micrometer and larger sized grains is estimated to be about 10(exp -4) cm(exp -3) in the plume while it is about 10(exp -6) - 10(exp -7) cm(exp -3) in the E-ring. Dust charge for micron sized grains is estimated to be about eight thousand electron charges reducing to below one hundred electron charges for 0.03 micron sized grains. The effective dusty plasma Debye length is estimated and compared with intergrain distance as well as the electron Debye length. The maximum dust charging time of 1.4 h is found for 0.03 11mmicron sized grains just 1 min before the closest approach. The charging time decreases substantially in the plume where it is only a fraction of a second for 1 micron sized grains, 1 s for 0.l micron sized grains and about 10 s for 0.03 micron sized grains.

  11. Quasistationary Plasma Predator-Prey System of Coupled Turbulence, Drive, and Sheared E ×B Flow During High Performance DIII-D Tokamak Discharges

    NASA Astrophysics Data System (ADS)

    Barada, K.; Rhodes, T. L.; Burrell, K. H.; Zeng, L.; Bardóczi, L.; Chen, Xi; Muscatello, C. M.; Peebles, W. A.

    2018-03-01

    A new, long-lived limit cycle oscillation (LCO) regime has been observed in the edge of near zero torque high performance DIII-D tokamak plasma discharges. These LCOs are localized and composed of density turbulence, gradient drives, and E ×B velocity shear damping (E and B are the local radial electric and total magnetic fields). Density turbulence sequentially acts as a predator (via turbulence transport) of profile gradients and a prey (via shear suppression) to the E ×B velocity shear. Reported here for the first time is a unique spatiotemporal variation of the local E ×B velocity, which is found to be essential for the existence of this system. The LCO system is quasistationary, existing from 3 to 12 plasma energy confinement times (˜30 - 900 LCO cycles) limited by hardware constraints. This plasma system appears to contribute strongly to the edge transport in these high performance and transient-free plasmas, as evident from oscillations in transport relevant edge parameters at LCO time scale.

  12. The role of helium metastable states in radio-frequency driven helium-oxygen atmospheric pressure plasma jets: measurement and numerical simulation

    NASA Astrophysics Data System (ADS)

    Niemi, K.; Waskoenig, J.; Sadeghi, N.; Gans, T.; O'Connell, D.

    2011-10-01

    Absolute densities of metastable He(23S1) atoms were measured line-of-sight integrated along the discharge channel of a capacitively coupled radio-frequency driven atmospheric pressure plasma jet operated in technologically relevant helium-oxygen mixtures by tunable diode-laser absorption spectroscopy. The dependences of the He(23S1) density in the homogeneous-glow-like α-mode plasma with oxygen admixtures up to 1% were investigated. The results are compared with a one-dimensional numerical simulation, which includes a semi-kinetical treatment of the pronounced electron dynamics and the complex plasma chemistry (in total 20 species and 184 reactions). Very good agreement between measurement and simulation is found. The main formation mechanisms for metastable helium atoms are identified and analyzed, including their pronounced spatio-temporal dynamics. Penning ionization through helium metastables is found to be significant for plasma sustainment, while it is revealed that helium metastables are not an important energy carrying species into the jet effluent and therefore will not play a direct role in remote surface treatments.

  13. Bulk plasma fragmentation in a C4F8 inductively coupled plasma: A hybrid modeling study

    NASA Astrophysics Data System (ADS)

    Zhao, Shu-Xia; Zhang, Yu-Ru; Gao, Fei; Wang, You-Nian; Bogaerts, Annemie

    2015-06-01

    A hybrid model is used to investigate the fragmentation of C4F8 inductive discharges. Indeed, the resulting reactive species are crucial for the optimization of the Si-based etching process, since they determine the mechanisms of fluorination, polymerization, and sputtering. In this paper, we present the dissociation degree, the density ratio of F vs. CxFy (i.e., fluorocarbon (fc) neutrals), the neutral vs. positive ion density ratio, details on the neutral and ion components, and fractions of various fc neutrals (or ions) in the total fc neutral (or ion) density in a C4F8 inductively coupled plasma source, as well as the effect of pressure and power on these results. To analyze the fragmentation behavior, the electron density and temperature and electron energy probability function (EEPF) are investigated. Moreover, the main electron-impact generation sources for all considered neutrals and ions are determined from the complicated C4F8 reaction set used in the model. The C4F8 plasma fragmentation is explained, taking into account many factors, such as the EEPF characteristics, the dominance of primary and secondary processes, and the thresholds of dissociation and ionization. The simulation results are compared with experiments from literature, and reasonable agreement is obtained. Some discrepancies are observed, which can probably be attributed to the simplified polymer surface kinetics assumed in the model.

  14. Supplementation with Watermelon Extract Reduces Total Cholesterol and LDL Cholesterol in Adults with Dyslipidemia under the Influence of the MTHFR C677T Polymorphism.

    PubMed

    Massa, Nayara M L; Silva, Alexandre S; de Oliveira, Caio V C; Costa, Maria J C; Persuhn, Darlene C; Barbosa, Carlos V S; Gonçalves, Maria da C R

    2016-08-01

    Dyslipidemia and genetic polymorphisms are associated with increased risk for developing cardiovascular diseases, and watermelon appears to have the potential to improve hyperlipidemia due to the presence of nutrients such as arginine and citrulline. To test the hypolipidemic effect of watermelon extract (Citrullus lanatus) and the influence of the methylenetetrahydrofolate reductase genotype (MTHFR C677T) on supplementation response. This is an experimental clinical phase II randomized and double-blind study. Forty-three subjects with dyslipidemia were randomly divided into 2 groups: experimental (n = 22) and control (n = 21) groups. The subjects were supplemented daily for 42 days with 6 g of watermelon extract or a mixture of carbohydrates (sucrose/glucose/fructose). The use of watermelon extract reduced plasma total cholesterol (p < 0.05) and low-density lipoprotein (p < 0.01) without modifying triglycerides, high-density lipoprotein, and very low-density lipoprotein values. Only carriers of the T allele (MTHFR C677T) showed decreasing concentrations of low-density lipoprotein (p < 0.01). No changes in anthropometric parameters analyzed were observed. This is the first study to demonstrate the beneficial effect of the consumption of watermelon extract in reducing plasma levels of lipids in humans. The MTHFR C677T polymorphism did not affect the plasma lipid concentration but made individuals more responsive to treatment with watermelon. The consumption of this functional food represents an alternative therapy in the combined treatment of patients with dyslipidemia, promoting health and minimizing the development of risk factors for cardiovascular diseases.

  15. Effects of a cinnamon extract on plasma glucose, HbA, and serum lipids in diabetes mellitus type 2.

    PubMed

    Mang, B; Wolters, M; Schmitt, B; Kelb, K; Lichtinghagen, R; Stichtenoth, D O; Hahn, A

    2006-05-01

    According to previous studies, cinnamon may have a positive effect on the glycaemic control and the lipid profile in patients with diabetes mellitus type 2. The aim of this trial was to determine whether an aqueous cinnamon purified extract improves glycated haemoglobin A1c (HbA1c), fasting plasma glucose, total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL) and triacylglycerol concentrations in patients with type 2 diabetes. A total of 79 patients with diagnosed diabetes mellitus type 2 not on insulin therapy but treated with oral antidiabetics or diet were randomly assigned to take either a cinnamon extract or a placebo capsule three times a day for 4 months in a double-blind study. The amount of aqueous cinnamon extract corresponded to 3 g of cinnamon powder per day. The mean absolute and percentage differences between the pre- and post-intervention fasting plasma glucose level of the cinnamon and placebo groups were significantly different. There was a significantly higher reduction in the cinnamon group (10.3%) than in the placebo group (3.4%). No significant intragroup or intergroup differences were observed regarding HbA1c, lipid profiles or differences between the pre- and postintervention levels of these variables. The decrease in plasma glucose correlated significantly with the baseline concentrations, indicating that subjects with a higher initial plasma glucose level may benefit more from cinnamon intake. No adverse effects were observed. The cinnamon extract seems to have a moderate effect in reducing fasting plasma glucose concentrations in diabetic patients with poor glycaemic control.

  16. Hepatic Effects of Estrogen on Plasma Distribution of Small Dense Low-Density Lipoprotein and Free Radical Production in Postmenopausal Women.

    PubMed

    Nii, Shota; Shinohara, Koichi; Matsushita, Hiroshi; Noguchi, Yasuyuki; Watanabe, Kazushi; Wakatsuki, Akihiko

    2016-07-01

    Hepatic effects of estrogen therapy on low-density lipoprotein (LDL) subfraction or oxidative stress have not been previously evaluated. The purpose of the present study was to investigate whether the differential hepatic effects of estrogen affect plasma distribution of small dense LDL and free radical production in postmenopausal women. In all, 45 postmenopausal women were given 0.625 mg/day of oral conjugated equine estrogen (CEE) (n=15), 1.0 mg/day of oral 17β estradiol (E2) (n=15), or 50 μg/day of transdermal 17βE2 (n=15) for 3 months. Subjects received either estrogen alone or with dydrogesterone at 5 mg/day. Plasma concentrations of sex hormone-binding globulin (SHBG), lipids, metallic ions, and derivatives of reactive oxygen metabolites (d-ROMs) were measured. CEE, but not oral 17βE2, increased the plasma concentrations of triglyceride, copper (Cu), and d-ROMs and the ratio of small dense LDL/total LDL cholesterol, a marker for plasma distribution of small dense LDL. Transdermal 17βE2 decreased d-ROMs concentrations but did not significantly change other parameters. Plasma concentrations of SHBG increased in the 3 groups. Estrogen-induced changes in triglyceride correlated positively either with changes in SHBG (R=0.52, P=0.0002) or the ratio of small dense LDL/total LDL cholesterol (R=0.65, P<0.0001). Changes in Cu also correlated positively either with changes in SHBG (R=0.85, P<0.0001) or d-ROMs (R=0.86, P<0.0001). The hepatic effects of different routes or types of estrogen therapy may be associated with plasma distribution of small dense LDL and free radical production in postmenopausal women.

  17. Silicon etching of difluoromethane atmospheric pressure plasma jet combined with its spectroscopic analysis

    NASA Astrophysics Data System (ADS)

    Sung, Yu-Ching; Wei, Ta-Chin; Liu, You-Chia; Huang, Chun

    2018-06-01

    A capacitivly coupled radio-frequency double-pipe atmospheric-pressure plasma jet is used for etching. An argon carrier gas is supplied to the plasma discharge jet; and CH2F2 etch gas is inserted into the plasma discharge jet, near the silicon substrate. Silicon etchings rate can be efficiently-controlled by adjusting the feeding etching gas composition and plasma jet operating parameters. The features of silicon etched by the plasma discharge jet are discussed in order to spatially spreading plasma species. Electronic excitation temperature and electron density are detected by increasing plasma power. The etched silicon profile exhibited an anisotropic shape and the etching rate was maximum at the total gas flow rate of 4500 sccm and CH2F2 concentration of 11.1%. An etching rate of 17 µm/min was obtained at a plasma power of 100 W.

  18. Uranium plasma emission at gas-core reaction conditions

    NASA Technical Reports Server (NTRS)

    Williams, M. D.; Jalufka, N. W.; Hohl, F.; Lee, J. H.

    1976-01-01

    The results of uranium plasma emission produced by two methods are reported. For the first method a ruby laser was focused on the surface of a pure U-238 sample to create a plasma plume with a peak plasma density of about 10 to the 20th power/cu cm and a temperature of about 38,600 K. The absolute intensity of the emitted radiation, covering the range from 300 to 7000 A was measured. For the second method, the uranium plasma was produced in a 20 kilovolt, 25 kilojoule plasma-focus device. The 2.5 MeV neutrons from the D-D reaction in the plasma focus are moderated by polyethylene and induce fissions in the U-235. Spectra of both uranium plasmas were obtained over the range from 30 to 9000 A. Because of the low fission yield the energy input due to fissions is very small compared to the total energy in the plasma.

  19. Randomized Double-Blind Placebo-Controlled Trial of Powdered Brassica rapa Ethanol Extract on Alteration of Body Composition and Plasma Lipid and Adipocytokine Profiles in Overweight Subjects

    PubMed Central

    Jeon, Seon-Min; Kim, Ji-Eun; Shin, Su-kyung; Kwon, Eun-young; Jung, Un Ju; Baek, Nam-In; Lee, Kyung-Tae; Jeong, Tae-Sook; Chung, Hae-Gon

    2013-01-01

    Abstract We evaluated the effects of Brassica rapa ethanol extract (BREE) on body composition and plasma lipid profiles through a randomized, double-blind, and placebo-controlled trial in overweight subjects. Fifty-eight overweight participants (age 20–50 years, body mass index23.0–24.9) were randomly assigned to two groups and served BREE (2 g/day) or placebo (starch, 2 g/day) for 10 weeks. Body compositions, nutrients intake, plasma lipids, adipocytokines, and hepatotoxicity biomarkers were assessed in all subjects at baseline and after 10 weeks of supplementation. The plasma total cholesterol (total-C) concentration was significantly increased after 10 weeks compared to the baseline in both groups. However, BREE supplementation significantly increased the high-density lipoprotein cholesterol (HDL-C) concentration and significantly reduced the total-C/HDL-C ratio, free fatty acid, and adipsin levels after 10 weeks. No significant differences were observed in body compositions, fasting blood glucose, plasma adipocytokines except adipsin, and aspartate aminotransferase and alanine aminotransferase activities between before and after trial within groups as well as between the two groups. The supplementation of BREE partially improves plasma lipid metabolism in overweight subjects without adverse effects. PMID:23342969

  20. Effects of dietary organic chromium and vitamin C supplementation on performance, immune responses, blood metabolites, and stress status of laying hens subjected to high stocking density.

    PubMed

    Mirfendereski, E; Jahanian, R

    2015-02-01

    The present study was carried out to investigate the effects of dietary supplementation of chromium-methionine (CrMet) and vitamin C (VC) on performance, immune response, and stress status of laying hens subjected to high stocking density. A total of 360 Hy-Line W-36 leghorn hens (at 26 wk old) were used in a 2×3×2 factorial arrangement that had 2 cage densities (5 and 7 hens per cage), 3 Cr levels (0, 500, and 1,000 ppb as CrMet), and 2 dietary VC levels (0 and 500 ppm as L-ascorbic acid). The trial lasted for 12 wk. The first 2 wk were for adaptation (26 to 28 wk of age), and the remaining 10 wk served as the main recording period. In addition to performance, immune response to Newcastle disease virus (NDV) was assessed at d 7 and 14 postvaccination. Also, the birds' stress status was evaluated by analyzing appropriate plasma metabolites. The results showed that hens in cages with higher stocking density had lower hen-day egg production, egg mass, and feed intake compared with those in normal density cages (P<0.05). Dietary CrMet supplementation caused significant increases in egg production and egg mass (P<0.01). There were significant Cr × VC interactions related to egg production and feed conversion efficiency (P<0.01); dietary CrMet supplementation was more effective in improving egg production and feed conversion ratio in VC-unsupplemented diets. Although plasma concentrations of triglycerides and high-density lipoproteins were not influenced by dietary treatments, supplemental CrMet decreased plasma cholesterol levels (P<0.05). Plasma insulin and glucose levels of hens kept at a density of 7 hens/cage were significantly higher than those of hens in normal cage density (P<0.01), and dietary CrMet supplementation decreased plasma concentrations of insulin (P<0.001) and glucose (P<0.01), with higher impacts in high stocking density-challenged hens. While high stocking density caused a marked increase in plasma corticosterone (P<0.01), both supplemental CrMet and VC decreased it to near normal levels. There were significant stocking density×Cr interactions related to plasma insulin and corticosterone concentrations (P<0.01); supplemental CrMet was more effective in lowering these hormones in high stocking density-challenged hens. The high stocking density challenge suppressed NDV antibody response (P<0.001), while dietary supplementation of CrMet improved antibody titers against NDV at d 14 post vaccination particularly in hens kept at a density of 7 hens/cage (P<0.01). From the present observations, it can be concluded that CrMet can improve laying performance largely because it alleviates harmful responses to stressful conditions. © 2015 Poultry Science Association Inc.

  1. Characteristics of a plasma flow field produced by a metal array bridge foil explosion

    NASA Astrophysics Data System (ADS)

    Junying, WU; Long, WANG; Yase, LI; Lijun, YANG; Manzoor, SULTAN; Lang, CHEN

    2018-07-01

    To improve the energy utilization efficiency of metal bridge foil explosion, and increase the function range of plasmas, array bridge foil explosion experiments with different structures were performed. A Schlieren photographic measurement system with a double-pulse laser source was used to observe the flow field of a bridge foil explosion. The evolution laws of plasmas and shock waves generated by array bridge foil explosions of different structures were analyzed and compared. A multi-phase flow calculation model was established to simulate the electrical exploding process of a metal bridge foil. The plasma equation of state was determined by considering the effect of the changing number of particles and Coulomb interaction on the pressure and internal energy. The ionization degree of the plasma was calculated via the Saha–Eggert equation assuming conditions of local thermal equilibrium. The exploding process of array bridge foils was simulated, and the superposition processes of plasma beams were analyzed. The variation and distribution laws of the density, temperature, pressure, and other important parameters were obtained. The results show that the array bridge foil has a larger plasma jet diameter than the single bridge foil for an equal total area of the bridge foil. We also found that the temperature, pressure, and density of the plasma jet’s center region sharply increase because of the superposition of plasma beams.

  2. Global plasma oscillations in electron internal transport barriers in TCV

    NASA Astrophysics Data System (ADS)

    Udintsev, V. S.; Sauter, O.; Asp, E.; Fable, E.; Goodman, T. P.; Turri, G.; Graves, J. P.; Scarabosio, A.; Zhuang, G.; Zucca, C.; TCV Team

    2008-12-01

    In the Tokamak à Configuration Variable (TCV) (Hofmann F et al1994 Plasma Phys. Control. Fusion 36 B277), global plasma oscillations have been discovered in fully non-inductively driven plasmas featuring electron internal transport barriers (ITB) with strong ECRH/ECCD. These oscillations are linked to the destabilization and stabilization of MHD modes near the foot of the ITB and can lead to large oscillations of the total plasma current and line-averaged density, among others. They are intrinsically related to the fact that ITBs have large pressure gradients in a region of low magnetic shear. Therefore, the ideal MHD limit is relatively low and infernal modes can be unstable. Depending on the proximity to the ideal limit, small crashes or resistive modes can appear which affect the time evolution of the discharge. Being near marginal stability, the modes can self-stabilize due to the modification of the pressure gradient and local q-profile. The plasma recovers good confinement, reverses shear and the ITB builds up, until a new MHD mode is destabilized. TCV results show that this cycling behaviour can be controlled by modifying the current density or the pressure profiles, either with Ohmic current density perturbation or by modifying the ECH/ECCD power. It is demonstrated that many observations such as q >= 2 sawteeth, beta collapses, minor disruptions and oscillation regimes in ITBs can be assigned to the same physics origin: the proximity to the infernal mode stability limit.

  3. Disassembly time of deuterium-cluster-fusion plasma irradiated by an intense laser pulse.

    PubMed

    Bang, W

    2015-07-01

    Energetic deuterium ions from large deuterium clusters (>10nm diameter) irradiated by an intense laser pulse (>10(16)W/cm(2)) produce DD fusion neutrons for a time interval determined by the geometry of the resulting fusion plasma. We present an analytical solution of this time interval, the plasma disassembly time, for deuterium plasmas that are cylindrical in shape. Assuming a symmetrically expanding deuterium plasma, we calculate the expected fusion neutron yield and compare with an independent calculation of the yield using the concept of a finite confinement time at a fixed plasma density. The calculated neutron yields agree quantitatively with the available experimental data. Our one-dimensional simulations indicate that one could expect a tenfold increase in total neutron yield by magnetically confining a 10-keV deuterium fusion plasma for 10ns.

  4. Measurement of the aerothermodynamic state in a high enthalpy plasma wind-tunnel flow

    NASA Astrophysics Data System (ADS)

    Hermann, Tobias; Löhle, Stefan; Zander, Fabian; Fasoulas, Stefanos

    2017-11-01

    This paper presents spatially resolved measurements of absolute particle densities of N2, N2+, N, O, N+ , O+ , e- and excitation temperatures of electronic, rotational and vibrational modes of an air plasma free stream. All results are based on optical emission spectroscopy data. The measured parameters are combined to determine the local mass-specific enthalpy of the free stream. The analysis of the radiative transport, relative and absolute intensities, and spectral shape is used to determine various thermochemical parameters. The model uncertainty of each analysis method is assessed. The plasma flow is shown to be close to equilibrium. The strongest deviations from equilibrium occur for N, N+ and N2+ number densities in the free stream. Additional measurements of the local mass-specific enthalpy are conducted using a mass injection probe as well as a heat flux and total pressure probe. The agreement between all methods of enthalpy determination is good.

  5. Apolipoprotein E isoforms 3/3 and 3/4 differentially interact with circulating stearic, palmitic, and oleic fatty acids and lipid levels in Alaskan Natives.

    PubMed

    Castellanos-Tapia, Lyssia; López-Alvarenga, Juan Carlos; Ebbesson, Sven O E; Ebbesson, Lars O E; Tejero, M Elizabeth

    2015-04-01

    Lifestyle changes in Alaskan Natives have been related to the increase of cardiovascular disease and metabolic syndrome in the last decades. Variation of the apolipoprotein E (Apo E) genotype may contribute to the diverse response to diet in lipid metabolism and influence the association between fatty acids in plasma and risk factors for cardiovascular disease. The aim of this investigation was to analyze the interaction between Apo E isoforms and plasma fatty acids, influencing phenotypes related to metabolic diseases in Alaskan Natives. A sample of 427 adult Siberian Yupik Alaskan Natives was included. Fasting glucose, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, Apo A1, and Apo B plasma concentrations were measured using reference methods. Concentrations of 13 fatty acids in fasting plasma were analyzed by gas chromatography, and Apo E variants were identified. Analyses of covariance were conducted to identify Apo E isoform and fatty acid main effects and multiplicative interactions. The means for body mass index and age were 26 ± 5.2 and 47 ± 1.5, respectively. Significant main effects were observed for variation in Apo E and different fatty acids influencing Apo B levels, triglycerides, and total cholesterol. Significant interactions were found between Apo E isoform and selected fatty acids influencing total cholesterol, triglycerides, and Apo B concentrations. In summary, Apo E3/3 and 3/4 isoforms had significant interactions with circulating levels of stearic, palmitic, oleic fatty acids, and phenotypes of lipid metabolism in Alaskan Natives. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. Influence of biological factors on lipid and fibrinogen measurements in young men. An epidemiological study in 2009 recruits.

    PubMed

    Pitsavos, C; Skoumas, J; Dernellis, J; Toutouza, M; Doulalas, A; Stefanadis, C; Toutouzas, P

    1998-11-01

    The aim of the present study was to detect significant relationships between lipid and fibrinogen measurements and several biological factors in young men. Medical history was obtained, and plasma lipids, lipoprotein (a) and fibrinogen levels were measured in 2009 male Greek army recruits (mean age 22.37+/-3.03 years) not taking any drugs. Plasma levels were as follows: total cholesterol, 171+/-34 mg x dl(-1), low density lipoprotein (LDL) cholesterol, 111+/-34 mg x dl(-1), high density lipoprotein (HDL) cholesterol, 45+/-10 mg x dl(1), and triglycerides, 74+/-32 mg x dl(-1). Lipoprotein (a) and fibrinogen were 18+/-13 and 278+/-67 mg x dl(-1). The atherosclerotic index, calculated as the ratio of total cholesterol/HDL, was 4+/-1. Analysis of multivariate models that included potentially confounding factors revealed the following: body mass index, season of year during which blood examinations were performed, alcohol consumption, and place of residence were found to be significantly associated with plasma levels of total cholesterol, LDL-cholesterol, fibrinogen and the atherosclerotic index in the pooled population. Season and physical activity were significantly associated with HDL-cholesterol, whereas season and family history of acute myocardial infarction were associated with triglycerides levels. Body mass index, family history of myocardial infarction and physical activity were associated with lipoprotein (a). Body mass index, season, alcohol consumption and place of residence are markers of plasma lipid profile and fibrinogen in young men. A family history of acute myocardial infarction and physical activity are related to lipoprotein (a).

  7. Study on electromagnetic plasma propulsion using rotating magnetic field acceleration scheme

    NASA Astrophysics Data System (ADS)

    Furukawa, T.; Takizawa, K.; Kuwahara, D.; Shinohara, S.

    2017-04-01

    As one of the electromagnetic plasma acceleration systems, we have proposed a rotating magnetic field (RMF) acceleration scheme to overcome the present problem of direct plasma-electrode interactions, leading to a short lifetime with a poor plasma performance due to contamination. In this scheme, we generate a plasma by a helicon wave excited by a radio frequency (rf) antenna which has no direct-contact with a plasma. Then, the produced plasma is accelerated by the axial Lorentz force fz = jθ × Br (jθ is an azimuthal current induced by RMF, and Br is an external radial magnetic field). Erosion of electrodes and contamination are not expected in this total system since RMF coils and an rf antenna do not have contact with the plasma directly. Here, we have measured the plasma parameters (electron density ne and axial ion velocity vi) to demonstrate this RMF acceleration scheme by the use of AC currents in two sets of opposing coils to generate a RMF. The maximum increasing rate Δvi /vi was ˜28% (maximum vi of ˜3 km/s), while the density increasing rate of Δne/ne is ˜ 70% in the case of a RMF current frequency fRMF of 3 MHz, which showed a better plasma performance than that with fRMF = 5 MHz. Moreover, thrust characteristics such as a specific impulse and a thrust efficiency were discussed, although a target plasma was not optimized.

  8. Measurements of Electron Density Profiles of Plasmas Produced by Nike KrF Laser for Laser Plasma Instability (LPI) Research

    NASA Astrophysics Data System (ADS)

    Oh, Jaechul; Weaver, J. L.; Obenschain, S. P.; Schmitt, A. J.; Kehne, D. M.; Karasik, M.; Chan, L.-Y.; Serlin, V.; Phillips, L.

    2013-10-01

    Knowing spatial profiles of electron density (ne) in the underdense coronal region (n

  9. Method of high-precision microsampled blood and plasma mass densitometry

    NASA Technical Reports Server (NTRS)

    Hinghofer-Szalkay, H.

    1986-01-01

    The reliability of the mechanical oscillator technique for blood and plasma density measurements on samples of volumes less than 0.1 ml is examined, and a precision of 0.001 g/l is found if plasma-isodensic heparin solution and siliconized densitometers are employed. Sources of measurement errors in the density determinations include storage of plasma samples, inhomogeneity of blood samples, and density reading before adequate temperature equilibration. In tests of plasma sample storage, the best reproducibility was obtained with samples kept at 4 C. Linear correlations were found between plasma density and plasma protein concentration, blood density and blood hemoglobin concentration, and erythrocyte density and MCHC.

  10. Effects of dietary copper and amino acid density on growth performance, apparent metabolizable energy, and nutrient digestibility in Eimeria acervulina-challenged broilers.

    PubMed

    Rochell, S J; Usry, J L; Parr, T M; Parsons, C M; Dilger, R N

    2017-03-01

    The objective of this experiment was to evaluate the influence of copper supplementation in diets varying in amino acid (AA) density on growth performance, apparent metabolizable energy (AMEn), apparent ileal nutrient digestibility (AID), and plasma carotenoids in broilers infected with Eimeria acervulina. Ross 308 male broilers (480 total) were housed in battery cages and allotted to 8 experimental treatments in a factorial arrangement of 2 dietary AA densities [1.00% (LAA) or 1.20% (HAA) digestible Lys], 2 supplemental copper concentrations (zero or 116 mg/kg), and 2 E. acervulina infection states (uninfected or infected). Essential AA ratios relative to digestible Lys were similar in both the LAA and HAA diets, and copper was provided by 200 mg/kg of tribasic copper chloride (58% copper). Chicks received experimental diets from 2 to 21 d post hatch and 6 replicate cages of 10 birds per cage were assigned to each treatment. Broilers were inoculated with zero or 6.3 × 105 sporulated E. acervulina oocysts at 15 d and blood and ileal digesta were collected at 21 days. From 2 to 15 d, body weight gain and G:F of broilers were improved (P < 0.05) with increasing AA density, and an AA density × copper interaction was observed (P < 0.05) for feed intake. Eimeria infection reduced (P < 0.05) plasma carotenoids, growth performance, dietary AMEn, and AID of organic matter, nitrogen, and total AA. There were no interactive effects of dietary treatments with E. acervulina infection on broiler growth performance or dietary AMEn. An AA density × copper supplementation interaction was observed (P < 0.05) for AID of total AA, whereby copper supplementation increased AID of total AA for birds fed the LAA diet and decreased AID of total AA for birds fed the HAA diet. In summary, E. acervulina-induced reductions in nutrient digestibility were dependent on dietary copper and AA status, but changes in digestibility had minimal impact on growth performance of broilers during the E. acervulina infection period. © 2016 Poultry Science Association Inc.

  11. Preparation of dielectric coating of variable dielectric constant by plasma polymerization

    NASA Technical Reports Server (NTRS)

    Hudis, M.; Wydeven, T. (Inventor)

    1979-01-01

    A plasma polymerization process for the deposition of a dielectric polymer coating on a substrate comprising disposing of the substrate in a closed reactor between two temperature controlled electrodes connected to a power supply is presented. A vacuum is maintained within the closed reactor, causing a monomer gas or gas mixture of a monomer and diluent to flow into the reactor, generating a plasma between the electrodes. The vacuum varies and controls the dielectric constant of the polymer coating being deposited by regulating the gas total and partial pressure, the electric field strength and frequency, and the current density.

  12. Physical Modeling of the Processes Responsible for the Mid-Latitude Storm Enhanced Plasma Density

    NASA Astrophysics Data System (ADS)

    Fuller-Rowell, T. J.; Maruyama, N.; Fedrizzi, M.; Codrescu, M.; Heelis, R. A.

    2016-12-01

    Certain magnetic local time sectors at mid latitudes see substantial increases in plasma density in the early phases of a geomagnetic storm. The St. Patrick's Day storms of 2013 and 2015 were no exception, both producing large increases of total electron content at mid latitudes. There are theories for the build up of the storm enhanced density (SED), but can current theoretical ionosphere-thermosphere coupled models actually reproduce the response for an actual event? Not only is it necessary for the physical model to contain the appropriate physics, they also have to be forced by the correct drivers. The SED requires mid-latitude zonal transport to provide plasma stagnation in sunlight to provide the production. The theory also requires a poleward drift perpendicular to the magnetic field to elevate the plasma out of the body of the thermosphere to regions of substantially less loss rate. It is also suggested that equatorward winds are necessary to further elevate the plasma to regions of reduced loss. However, those same winds are also likely to transport molecular nitrogen rich neutral gas equatorward, potentially canceling out the benefits of the neutral circulation. Observations of mid-latitude zonal plasma flow are first analyzed to see if this first necessary ingredient is substantiated. The drift observations are then used to tune the driver to determine if, with the appropriate electric field driver, the latest physical models can reproduce the substantial plasma build up. If it can, the simulation can also be used to assess the contribution of the equatorward meridional wind; are they an asset to the plasma build up, or does the enhanced molecular species they carry counteract their benefit.

  13. Regimes of enhanced electromagnetic emission in beam-plasma interactions

    NASA Astrophysics Data System (ADS)

    Timofeev, I. V.; Annenkov, V. V.; Arzhannikov, A. V.

    2015-11-01

    The ways to improve the efficiency of electromagnetic waves generation in laboratory experiments with high-current relativistic electron beams injected into a magnetized plasma are discussed. It is known that such a beam can lose, in a plasma, a significant part of its energy by exciting a high level of turbulence and heating plasma electrons. Beam-excited plasma oscillations may simultaneously participate in nonlinear processes resulting in a fundamental and second harmonic emissions. It is obvious, however, that in the developed plasma turbulence the role of these emissions in the total energy balance is always negligible. In this paper, we investigate whether electromagnetic radiation generated in the beam-plasma system can be sufficiently enhanced by the direct linear conversion of resonant beam-driven modes into electromagnetic ones on preformed regular inhomogeneities of plasma density. Due to the high power of relativistic electron beams, the mechanism discussed may become the basis for the generator of powerful sub-terahertz radiation.

  14. Deuterium retention and release behaviours of tungsten and deuterium co-deposited layers

    NASA Astrophysics Data System (ADS)

    Qiao, L.; Zhang, H. W.; Xu, J.; Chai, L. Q.; Hu, M.; Wang, P.

    2018-04-01

    Tungsten (W) layer deposited in argon and deuterium atmosphere by magnetron sputtering was used as a model system to study the deuterium (D) retention and release behavior in co-deposited W layer. After deposition several selected samples were exposed in deuterium plasma at 370 K with a flux of 4.0 × 1021 D/(m2 s) up to a fluence of 1.1 × 1025 D/m2. Structures of co-deposited W layers are investigated by field-emission scanning electron microscopy (FESEM) and X-ray diffraction (XRD), and the corresponding D retention and release behaviors are studied as functions of deposition and exposure parameters using thermal desorption spectroscopy (TDS). Two main D release peaks were detected from TDS spectra located near 600 and 800 K in these W and D co-deposited layers, and total deuterium retention increased linearly as a function of W layer's thickness. After deuterium plasma exposure, the total D retention amount in W layer increases significantly and D release peak shifts to lower temperature. Clearly, despite the high density of defects expected in co-deposited W layers, the initial deuterium retention before exposure to the deuterium plasma is low even for the samples with a W&D layer. But due to the high densities of defects, during the deuterium plasma exposure the deuterium retention increases faster for co-deposited layer than for the bulk W sample.

  15. Head fat is a novel method of measuring metabolic disorder in Chinese obese patients

    PubMed Central

    2014-01-01

    Background Body adiposity, especially ectopic fat accumulation, has a range of metabolic and cardiovascular effects. The aim of this study was to investigate the association between head fat and metabolic values in Chinese obese patients. Methods Data of this cross-sectional study from 66 obese patients were collected. Fat distribution was measured by dual-energy X-ray absorptiometry, and data of body weight, body mass index (BMI), neck circumference (NC), waist circumference (WC), hip circumference (HC), visceral index, basal metabolism (BM), glucose metabolism, lipid levels, uric acid (UA) had been collected. Results 1) Head fat was significantly associated with BMI, WC, HC, visceral index, BM, total fat and total fat excluding head fat in both males and females (p < 0.05). Head fat was positively correlated with upper limb fat, trunk fat, weight, fasting plasma C peptide, fasting plasma insulin and UA in women(p < 0.05), and the association was not statistically significant in male (p > 0.05). Head fat was positively corrected with NC in males (p < 0.05) but not females (p > 0.05). There was no significant correlation between head fat and fasting plasma glucose, total choleslerolemia, triglyceridemia, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and free fat acid in either gender (p > 0.05). 2) Receiver operating characteristic analysis showed that a head fat of 1925.6 g and a head fat of 1567.85 g were the best cut-off values to determine subjects with low high-density lipoprotein cholesterol and hyperuricemia respectively. Conclusions Head fat accumulation was closely associated with increased body fat, hyperinsulinemia, hyperuricemia, and impared lipid profile, suggesting it might be used as an indicator for dyslipidemia and hyperuricemia. PMID:25015267

  16. Fatty acid profile in patients with phenylketonuria and its relationship with bone mineral density.

    PubMed

    Lage, Sergio; Bueno, María; Andrade, Fernando; Prieto, José Angel; Delgado, Carmen; Legarda, María; Sanjurjo, Pablo; Aldámiz-Echevarría, Luis Jose

    2010-12-01

    Patients with phenylketonuria (PKU) undergo a restrictive vegan-like diet, with almost total absence of n-3 fatty acids, which have been proposed as potential contributors to bone formation in the healthy population. The PKU diet might lead these patients to bone mass loss and, consequently, to the development of osteopenia/osteoporosis. Therefore, we proposed to analyze their plasma fatty acid profile status and its relationship with bone health. We recruited 47 PKU patients for this cross-sectional study and divided the cohort into three age groups (6-10 years, 11-18 years, 19-42 years). We measured their plasma fatty acid profile and bone mineral density (BMD) (both at the femoral neck and the lumbar spine). Seventy-seven healthy controls also participated as reference values of plasma fatty acids. Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) and total n-3 fatty acids were significantly diminished in PKU patients compared with healthy controls. DHA, EPA, and total n-3 fatty acids were also positively associated with bone mineral density (r = 0.83, p = 0.010; r = 0.57, p = 0.006; r = 0.73, p = 0.040, respectively). There was no association between phenylalanine (Phe), Index of Dietary Control (IDC), calcium, 25-hydroxivitamin D concentrations, daily calcium intake, and BMD. Our results suggest a possible influence of essential fatty acids over BMD in PKU patients. The lack of essential n-3 fatty acids intake in the PKU diet might affect bone mineralization. Further clinical trials are needed to confirm the effect of the n-3 essential fatty acids on bone accrual in a cohort of PKU patients.

  17. Lack of effect of dietary fiber on serum lipids, glucose, and insulin in healthy young men fed high starch diets.

    PubMed

    Ullrich, I H; Albrink, M J

    1982-07-01

    Eight healthy young men were fed a 72% carbohydrate high starch diet either high or low in dietary fiber for 4 days in a double cross-over design. Both groups showed a slight transient increase in plasma triglyceride level and a decrease in total and high-density lipoprotein cholesterol. There were few differences in glucose and insulin levels after glucose and meal tolerance tests after each diet. Fasting triglycerides and high-density lipoprotein cholesterol were inversely related at base-line; insulin response to oral glucose was inversely related to high-density lipoprotein cholesterol levels at the end of the study. We conclude that a high carbohydrate high starch diet, whether high or low in fiber, caused little increase in triglycerides, with little difference between the high and low fiber diets. Dietary fiber did not influence the fall in plasma cholesterol or high-density lipoprotein cholesterol concentrations over and above that seen after the low fiber diet.

  18. Discharge dynamics and plasma density recovery by on/off switches of additional gas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, Hyo-Chang, E-mail: lhc@kriss.re.kr; Department of Electrical Engineering, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul 04763; Kwon, Deuk-Chul

    2016-06-15

    Measurement of the plasma density is investigated to study plasma dynamics by adding reactive gas (O{sub 2}) or rare gas (He) in Ar plasmas. When the O{sub 2} or He gas is added, plasma density is suddenly decreased, while the plasma density recovers slowly with gas off. It is found that the recovery time is strongly dependent on the gas flow rate, and it can be explained by effect of gas residence time. When the He gas is off in the Ar plasma, the plasma density is overshot compared to the case of the O{sub 2} gas pulsing due tomore » enhanced ionizations by metastable atoms. Analysis and calculation for correlation between the plasma density dynamics and the gas pulsing are also presented in detail.« less

  19. Influence of dietary soybean and egg lecithins on lipid responses in cholesterol-fed guinea pigs.

    PubMed

    O'Brien, B C; Corrigan, S M

    1988-07-01

    The comparative influence on plasma and tissue lipids of dietary soybean and egg lecithins, which have contrasting fatty acid compositions, was studied in the hypercholesterolemic guinea pig. The polyunsaturated to saturated fatty acid (P/S) ratios of the soybean and egg lecithins were 3.4 and 0.38, respectively. Hypercholesterolemia was induced by feeding guinea pigs a purified diet that contained 15% lard enriched with 0.5% cholesterol. Subsequently, guinea pigs were fed for six wk the same diet supplemented with either soybean or egg lecithin as 7.5% of the diet. A control group continued to be fed the lecithin-free diet. Parameters measured included body weight and relative liver weight; in plasma, total cholesterol, high density lipoprotein cholesterol (HDLC), phospholipid, and nonesterified cholesterol; in liver, total fat, cholesterol, and the specific activity of the catabolic enzyme cholesterol 7 alpha-hydroxylase; (EC 1.14.13.17); and in the aorta, cholesterol. Among the most noteworthy observations were the 49% decrease in total plasma cholesterol of the soybean lecithin group without decreasing HDLC and the 177% increase in HDLC of the egg lecithin group without a significant increase in total cholesterol compared with those values in the control group. These data suggest that dietary lecithin is particularly effective in increasing the HDLC/total cholesterol ratio in plasma. However, the absolute concentrations of those plasma lipids seem to depend upon the fatty acid composition of the lecithin.

  20. Density and temperature characterization of long-scale length, near-critical density controlled plasma produced from ultra-low density plastic foam

    PubMed Central

    Chen, S. N.; Iwawaki, T.; Morita, K.; Antici, P.; Baton, S. D.; Filippi, F.; Habara, H.; Nakatsutsumi, M.; Nicolaï , P.; Nazarov, W.; Rousseaux, C.; Starodubstev, M.; Tanaka, K. A.; Fuchs, J.

    2016-01-01

    The ability to produce long-scale length (i.e. millimeter scale-length), homogeneous plasmas is of interest in studying a wide range of fundamental plasma processes. We present here a validated experimental platform to create and diagnose uniform plasmas with a density close or above the critical density. The target consists of a polyimide tube filled with an ultra low-density plastic foam where it was heated by x-rays, produced by a long pulse laser irradiating a copper foil placed at one end of the tube. The density and temperature of the ionized foam was retrieved by using x-ray radiography and proton radiography was used to verify the uniformity of the plasma. Plasma temperatures of 5–10 eV and densities around 1021 cm−3 are measured. This well-characterized platform of uniform density and temperature plasma is of interest for experiments using large-scale laser platforms conducting High Energy Density Physics investigations. PMID:26923471

  1. Impact of plasma viscosity on microcirculatory flow after traumatic haemorrhagic shock: A prospective observational study.

    PubMed

    Naumann, David N; Hazeldine, Jon; Bishop, Jon; Midwinter, Mark J; Harrison, Paul; Nash, Gerard; Hutchings, Sam D

    2018-05-19

    Preclinical studies report that higher plasma viscosity improves microcirculatory flow after haemorrhagic shock and resuscitation, but no clinical study has tested this hypothesis. We investigated the relationship between plasma viscosity and sublingual microcirculatory flow in patients during resuscitation for traumatic haemorrhagic shock (THS). Sublingual video-microscopy was performed for 20 trauma patients with THS as soon as feasible in hospital, and then at 24 h and 48 h. Values were obtained for total vessel density, perfused vessel density, proportion of perfused vessels, microcirculatory flow index (MFI), microcirculatory heterogeneity index (MHI), and Point of Care Microcirculation (POEM) scores. Plasma viscosity was measured using a Wells-Brookfield cone and plate micro-viscometer. Logistic regression analyses examined relationships between microcirculatory parameters and plasma viscosity, adjusting for covariates (systolic blood pressure, heart rate, haematocrit, rate and volume of fluids, and rate of noradrenaline). Higher plasma viscosity was not associated with improved microcirculatory parameters. Instead, there were weakly significant associations between higher plasma viscosity and lower (poorer) MFI (p = 0.040), higher (worse) MHI (p = 0.033), and lower (worse) POEM scores (p = 0.039). The current study did not confirm the hypothesis that higher plasma viscosity improves microcirculatory flow dynamics in patients with THS. Further clinical investigations are warranted to determine whether viscosity is a physical parameter of importance during resuscitation of these patients.

  2. Double ion production in mercury thrusters. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Peters, R. R.

    1976-01-01

    The development of a model which predicts doubly charged ion density is discussed. The accuracy of the model is shown to be good for two different thruster sizes and a total of 11 different cases. The model indicates that in most cases more than 80% of the doubly charged ions are produced from singly charged ions. This result can be used to develop a much simpler model which, along with correlations of the average plasma properties, can be used to determine the doubly charged ion density in ion thrusters with acceptable accuracy. Two different techniques which can be used to reduce the doubly charged ion density while maintaining good thruster operation, are identified as a result of an examination of the simple model. First, the electron density can be reduced and the thruster size then increased to maintain the same propellant utilization. Second, at a fixed thruster size, the plasma density, temperature and energy can be reduced and then to maintain a constant propellant utilization the open area of the grids to neutral propellant loss can be reduced through the use of a small hole accelerator grid.

  3. Model-based Optimization and Feedback Control of the Current Density Profile Evolution in NSTX-U

    NASA Astrophysics Data System (ADS)

    Ilhan, Zeki Okan

    Nuclear fusion research is a highly challenging, multidisciplinary field seeking contributions from both plasma physics and multiple engineering areas. As an application of plasma control engineering, this dissertation mainly explores methods to control the current density profile evolution within the National Spherical Torus eXperiment-Upgrade (NSTX-U), which is a substantial upgrade based on the NSTX device, which is located in Princeton Plasma Physics Laboratory (PPPL), Princeton, NJ. Active control of the toroidal current density profile is among those plasma control milestones that the NSTX-U program must achieve to realize its next-step operational goals, which are characterized by high-performance, long-pulse, MHD-stable plasma operation with neutral beam heating. Therefore, the aim of this work is to develop model-based, feedforward and feedback controllers that can enable time regulation of the current density profile in NSTX-U by actuating the total plasma current, electron density, and the powers of the individual neutral beam injectors. Motivated by the coupled, nonlinear, multivariable, distributed-parameter plasma dynamics, the first step towards control design is the development of a physics-based, control-oriented model for the current profile evolution in NSTX-U in response to non-inductive current drives and heating systems. Numerical simulations of the proposed control-oriented model show qualitative agreement with the high-fidelity physics code TRANSP. The next step is to utilize the proposed control-oriented model to design an open-loop actuator trajectory optimizer. Given a desired operating state, the optimizer produces the actuator trajectories that can steer the plasma to such state. The objective of the feedforward control design is to provide a more systematic approach to advanced scenario planning in NSTX-U since the development of such scenarios is conventionally carried out experimentally by modifying the tokamak's actuator trajectories and analyzing the resulting plasma evolution. Finally, the proposed control-oriented model is embedded in feedback control schemes based on optimal control and Model Predictive Control (MPC) approaches. Integrators are added to the standard Linear Quadratic Gaussian (LQG) and MPC formulations to provide robustness against various modeling uncertainties and external disturbances. The effectiveness of the proposed feedback controllers in regulating the current density profile in NSTX-U is demonstrated in closed-loop nonlinear simulations. Moreover, the optimal feedback control algorithm has been implemented successfully in closed-loop control simulations within TRANSP through the recently developed Expert routine. (Abstract shortened by ProQuest.).

  4. Properties of the Products Formed by the Activity of Serum Opacity Factor against Human Plasma High Density Lipoproteins

    PubMed Central

    Pownall, Henry J.; Courtney, Harry S.; Gillard, Baiba K.; Massey, John B.

    2010-01-01

    Serum opacity factor from Streptococcus pyogenes transfers the cholesteryl esters (CE) of ~100,000 plasma high density lipoprotein particles (HDL) to a CE-rich microemulsion (CERM) while forming neo HDL, a cholesterol-poor HDL-like particle. HDL, neo HDL, and CERM are distinct. Neo HDL is lower in free cholesterol and has lower surface and total microviscosities than HDL; the surface polarity of neo HDL and HDL are similar. CERM is much larger than HDL and richer in cholesterol and CE. Although the surface microviscosity of HDL is higher than that of CERM, they have similar total microviscosities because cholesterol partitions into the neutral lipid core. Because of its unique surface properties apo E preferentially associates with the CERM. In contrast, the composition and properties of neo HDL make it a potential acceptor of cellular cholesterol and its esterification. Thus, neo HDL and CERM are possible vehicles for improving cholesterol transport to the liver. PMID:18838065

  5. Relationship between the concentrations of plasma phospholipid stearic acid and plasma lipoprotein lipids in healthy men.

    PubMed

    Li, D

    2001-01-01

    This study investigated the correlation between the plasma phospholipid (PL) saturated fatty acid (SFA) concentration (as a surrogate marker of SFA intake) and plasma lipid and lipoprotein lipid concentrations in 139 healthy Australian men aged 20-55 years old with widely varying intakes of saturated fat (vegans, n=18; ovolacto vegetarians, n=43; moderate meat eaters, n=60; high meat eaters, n=18). Both the ovolacto vegetarian and vegan groups demonstrated significant decreases in plasma total cholesterol (TC), low-density-lipoprotein cholesterol (LDL-C) and triacylglycerol concentrations compared with both the high-meat-eater and moderate-meat-eater groups. Total SFA and individual SFA [palmitic acid (16:0), stearic acid (18:0) and arachidic acid (20:0)] in the plasma PL were significantly lower in both the ovolacto vegetarian and vegan groups than in both the high- and moderate-meat-eater groups, while myristic acid (14:0) was significantly lower in the vegans than in the high-meat-eaters. Bivariate analysis of the results showed that the plasma PL stearic acid concentration was strongly positively correlated with plasma TC (P<0.0001), LDL-C (P<0.0001) and triacylglycerol (P<0.0001), with r(2) values of 0.655, 0.518 and 0.43 respectively. In multiple linear regression, after controlling for potential confounding factors (such as exercise, dietary group, age, body mass index, plasma PL myristic acid, palmitic acid and arachidic acid, and dietary total fat, saturated fat, cholesterol, carbohydrate and fibre intake), the plasma PL stearic acid concentration was still strongly positively correlated with plasma TC (P<0.0001) and LDL-C (P=0.006) concentrations. Based on the present data, it would seem appropriate for the population to reduce their dietary total SFA intake rather than to replace other SFA with stearic acid.

  6. The Plasma Environment at Enceladus

    NASA Astrophysics Data System (ADS)

    Rymer, Abigail; Morooka, Michiko; Persoon, Ann

    2016-10-01

    The plasma environment near Enceladus is complex. The well documented Enceladus plumes create a dusty, asymmetric exosphere in which electrons can attach to small ice particles - forming anions, and negatively charged nanograins and dust - to the extent that cations can be the lightest charged particles present and, as a result, the dominant current carriers. Several instruments on the Cassini spacecraft are able to measure this environment in both expected and unexpected ways. Cassini Plasma Spectrometer (CAPS) is designed and calibrated to measure the thermal plasma ions and electrons and also measures the energy/charge of charged nanograins when present. Cassini Radio Plasma Wave Sensor (RPWS) measures electron density as derived from the 'upper hybrid frequency' which is a function of the total free electron density and magnetic field strength and provides a vital ground truth measurement for Cassini calibration when the density is sufficiently high for it to be well measured. Cassini Langmuir Probe (LP) measures the electron density and temperature via direct current measurement, and both CAPS and LP can provide estimates for the spacecraft potential which we compare. Cassini Magnetospheric Imaging Instrument (MIMI) directly measures energetic particles that are manifest in the CAPS measurements as penetrating background in this region and, while not particularly efficient ionisers, create sputtering and surface weathering of Enceladus surface, MIMI also measures energetic neutral atoms produced during the charge exchange interactions in and near the plumes.In this presentation we exploit two almost identical Cassini-Enceladus flybys 'E17' and 'E18' which took place in March/April 2012. We present a detailed comparison of data from these Cassini sensors in order to assess the plasma environment observed by the different instruments, discuss what is consistent and otherwise, and the implications for the plasma environment at Enceladus in the context of work to date as well as implications for future studies.

  7. Time analysis of volcanic activity on Io by means of plasma observations

    NASA Technical Reports Server (NTRS)

    Mekler, Y.; Eviatar, A.

    1980-01-01

    A model of Io volcanism in which the probability of activity obeys a binomial distribution is presented. Observed values of the electron density obtained over a 3-year period by ground-based spectroscopy are fitted to such a distribution. The best fit is found for a total number of 15 volcanoes with a probability of individual activity at any time of 0.143. The Pioneer 10 ultraviolet observations are reinterpreted as emissions of sulfur and oxygen ions and are found to be consistent with a plasma much less dense than that observed by the Voyager spacecraft. Late 1978 and the first half of 1979 are shown to be periods of anomalous volcanicity. Rapid variations in electron density are related to enhanced radial diffusion.

  8. Influence of adiponectin gene polymorphism SNP276 (G/T) on adiponectin in response to exercise training.

    PubMed

    Huang, Hu; Tada Iida, Kaoruko; Murakami, Haruka; Saito, Yoko; Otsuki, Takeshi; Iemitsu, Motoyuki; Maeda, Seiji; Sone, Hirohito; Kuno, Shinya; Ajisaka, Ryuichi

    2007-12-01

    Adiponectin is an adipocytokine that is involved in insulin sensitivity. The adiponectin gene contains a single nucleotide polymorphism (SNP) at position 276 (G/T). The GG genotype of SNP276 (G/T) is associated with lower plasma adiponectin levels and a higher insulin resistance index. Therefore, we examined the influence of SNP276 (G/T) on the plasma level of adiponectin in response to exercise training. Thirty healthy Japanese (M12/F18; 56 to 79 years old) performed both resistance and endurance training, 5 times a week for 6 months. The work rate per kg of weight at double-product break-point (DPBP) was measured. Blood samples were obtained before and after the experiment. Plasma concentrations of adiponectin, HbA1c, insulin, glucose, total, high-density lipoprotein (HDL), and low-density lipoprotein (LDL) cholesterol, and triglyceride were measured. Genotypes of SNP276 were specified. Student's t-test for paired values and unpaired values was used. After the 6-month training period, the work rate per kg of weight at DPBP and the plasma HDL-cholesterol level were significantly improved (P<0.05), while no change was observed in the total plasma adiponectin level. However, the plasma adiponectin level in those with the GT + TT genotype had significantly increased (P<0.05). Additionally, the degree of the decrease in the HOMA-R level was significantly greater in the subjects with the GT + TT genotype than those with the GG genotype (p<0.05). Our results suggest that subjects with the genotype GT + TT at SNP276 (G/T) have a greater adiponectin-related response to exercise training than those with the GG genotype.

  9. Pair plasma relaxation time scales.

    PubMed

    Aksenov, A G; Ruffini, R; Vereshchagin, G V

    2010-04-01

    By numerically solving the relativistic Boltzmann equations, we compute the time scale for relaxation to thermal equilibrium for an optically thick electron-positron plasma with baryon loading. We focus on the time scales of electromagnetic interactions. The collisional integrals are obtained directly from the corresponding QED matrix elements. Thermalization time scales are computed for a wide range of values of both the total-energy density (over 10 orders of magnitude) and of the baryonic loading parameter (over 6 orders of magnitude). This also allows us to study such interesting limiting cases as the almost purely electron-positron plasma or electron-proton plasma as well as intermediate cases. These results appear to be important both for laboratory experiments aimed at generating optically thick pair plasmas as well as for astrophysical models in which electron-positron pair plasmas play a relevant role.

  10. Effects of Dietary Lycopene Supplementation on Plasma Lipid Profile, Lipid Peroxidation and Antioxidant Defense System in Feedlot Bamei Lamb.

    PubMed

    Jiang, Hongqin; Wang, Zhenzhen; Ma, Yong; Qu, Yanghua; Lu, Xiaonan; Luo, Hailing

    2015-07-01

    Lycopene, a red non-provitamin A carotenoid, mainly presenting in tomato and tomato byproducts, has the highest antioxidant activity among carotenoids because of its high number of conjugated double bonds. The objective of this study was to investigate the effect of lycopene supplementation in the diet on plasma lipid profile, lipid peroxidation and antioxidant defense system in feedlot lamb. Twenty-eight Bamei male lambs (90 days old) were divided into four groups and fed a basal diet (LP0, 40:60 roughage: concentrate) or the basal diet supplemented with 50, 100, and 200 mg/kg lycopene. After 120 days of feeding, all lambs were slaughtered and sampled. Dietary lycopene supplementation significantly reduced the levels of plasma total cholesterol (p<0.05, linearly), total triglycerides (TG, p<0.05) and low-density lipoprotein cholesterol (LDL-C, p<0.05), as well as atherogenic index (p<0.001), whereas no change was observed in high-density lipoprotein cholesterol (p>0.05). The levels of TG (p<0.001) and LDL-C (p<0.001) were decreased with the feeding time extension, and both showed a linear trend (p<0.01). Malondialdehyde level in plasma and liver decreased linearly with the increase of lycopene inclusion levels (p<0.01). Dietary lycopene intake linearly increased the plasma antioxidant vitamin E level (p<0.001), total antioxidant capacity (T-AOC, p<0.05), and activities of catalase (CAT, p<0.01), glutathione peroxidase (GSH-Px, p<0.05) and superoxide dismutase (SOD, p<0.05). The plasma T-AOC and activities of GSH-Px and SOD decreased with the extension of the feeding time. In liver, dietary lycopene inclusion showed similar antioxidant effects with respect to activities of CAT (p<0.05, linearly) and SOD (p<0.001, linearly). Therefore, it was concluded that lycopene supplementation improved the antioxidant status of the lamb and optimized the plasma lipid profile, the dosage of 200 mg lycopene/kg feed might be desirable for growing lambs to prevent environment stress and maintain normal physiological metabolism.

  11. Disassembly time of deuterium-cluster-fusion plasma irradiated by an intense laser pulse

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bang, W.

    Energetic deuterium ions from large deuterium clusters (>10 nm diameter) irradiated by an intense laser pulse (>10¹⁶ W/cm²) produce DD fusion neutrons for a time interval determined by the geometry of the resulting fusion plasma. We show an analytical solution of this time interval, the plasma disassembly time, for deuterium plasmas that are cylindrical in shape. Assuming a symmetrically expanding deuterium plasma, we calculate the expected fusion neutron yield and compare with an independent calculation of the yield using the concept of a finite confinement time at a fixed plasma density. The calculated neutron yields agree quantitatively with the availablemore » experimental data. Our one-dimensional simulations indicate that one could expect a tenfold increase in total neutron yield by magnetically confining a 10 - keV deuterium fusion plasma for 10 ns.« less

  12. Disassembly time of deuterium-cluster-fusion plasma irradiated by an intense laser pulse

    DOE PAGES

    Bang, W.

    2015-07-02

    Energetic deuterium ions from large deuterium clusters (>10 nm diameter) irradiated by an intense laser pulse (>10¹⁶ W/cm²) produce DD fusion neutrons for a time interval determined by the geometry of the resulting fusion plasma. We show an analytical solution of this time interval, the plasma disassembly time, for deuterium plasmas that are cylindrical in shape. Assuming a symmetrically expanding deuterium plasma, we calculate the expected fusion neutron yield and compare with an independent calculation of the yield using the concept of a finite confinement time at a fixed plasma density. The calculated neutron yields agree quantitatively with the availablemore » experimental data. Our one-dimensional simulations indicate that one could expect a tenfold increase in total neutron yield by magnetically confining a 10 - keV deuterium fusion plasma for 10 ns.« less

  13. Waves generated in the plasma plume of helicon magnetic nozzle

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Singh, Nagendra; Rao, Sathyanarayan; Ranganath, Praveen

    2013-03-15

    Experimental measurements have shown that the plasma plume created in a helicon plasma device contains a conical structure in the plasma density and a U-shaped double layer (US-DL) tightly confined near the throat where plasma begins to expand from the source. Recently reported two-dimensional particle-in-cell simulations verified these density and US-DL features of the plasma plume. Simulations also showed that the plasma in the plume develops non-thermal feature consisting of radial ion beams with large densities near the conical surface of the density structure. The plasma waves that are generated by the radial ion beams affecting the structure of themore » plasma plume are studied here. We find that most intense waves persist in the high-density regions of the conical density structure, where the transversely accelerated ions in the radial electric fields in the plume are reflected setting up counter-streaming. The waves generated are primarily ion Bernstein modes. The nonlinear evolution of the waves leads to magnetic field-aligned striations in the fields and the plasma near the conical surface of the density structure.« less

  14. Dietary protein level and origin (casein and highly purified soybean protein) affect hepatic storage, plasma lipid transport, and antioxidative defense status in the rat.

    PubMed

    Madani, S; Prost, J; Belleville, J

    2000-05-01

    The effects of different proportions (10, 20, and 30%) of dietary casein or highly purified soybean protein on lipid metabolism were studied in growing Wistar rats. Hepatic, plasma and lipoprotein lipid, and protein concentrations, plasma thiobarbituric acid-reactive substance (TBARS) levels, and resistance of red blood cells against free-radical attack were determined after a 4-wk dietary regimen. Compared with the 20% casein diet, the 20% soybean protein diet exhibited similar cholesterolemia but lower plasma triacylglycerol concentrations and very-low-density lipoprotein (VLDL) particle number, as measured by diminished contents of VLDL-triacylglycerol, VLDL-protein, and VLDL-apolipoprotein (Apo) B (B-100 and B-48). The soybean protein diet raised high-density lipoprotein (HDL)(2-3) particle number, as measured by enhanced concentrations of HDL(2-3) cholesterol, HDL-phospholipid, and HDL-ApoA-I. Increasing casein or soybean protein level (from 10 to 30%) in the diet involved higher VLDL-ApoB (B-100 and B-48), indicating an increase in the number of VLDL particles. Feeding the 30% casein or 30% soybean protein diet enhanced LDL-HDL(1) cholesterol contents. Despite similar HDL(2-3)-ApoA-I levels, the 30% casein diet enhanced the HDL(2-3) mass and its cholesterol concentrations. In contrast, feeding either the 10 or 30% soybean protein diet significantly lowered HDL(2-3) cholesterol and ApoA-I levels. These effects on cholesterol distribution in lipoprotein fractions occurred despite unchanged total cholesterol concentrations in plasma. Feeding 20% soybean protein versus 20% casein involved lower plasma TBARS concentrations. Decreasing casein or soybean protein levels in the diet were associated with higher plasma TBARS concentrations and had a lower resistance of red blood cells against free-radical attack. The present study shows that dietary protein level and origin play an important role in lipoprotein metabolism and the antioxidative defense status but do not affect total cholesterol concentrations in plasma.

  15. Test of bootstrap current models using high- β p EAST-demonstration plasmas on DIII-D

    DOE PAGES

    Ren, Qilong; Lao, Lang L.; Garofalo, Andrea M.; ...

    2015-01-12

    Magnetic measurements together with kinetic profile and motional Stark effect measurements are used in full kinetic equilibrium reconstructions to test the Sauter and NEO bootstrap current models in a DIII-D high-more » $${{\\beta}_{\\text{p}}}$$ EAST-demonstration experiment. This aims at developing on DIII-D a high bootstrap current scenario to be extended on EAST for a demonstration of true steady-state at high performance and uses EAST-similar operational conditions: plasma shape, plasma current, toroidal magnetic field, total heating power and current ramp-up rate. It is found that the large edge bootstrap current in these high-$${{\\beta}_{\\text{p}}}$$ plasmas allows the use of magnetic measurements to clearly distinguish the two bootstrap current models. In these high collisionality and high-$${{\\beta}_{\\text{p}}}$$ plasmas, the Sauter model overpredicts the peak of the edge current density by about 30%, while the first-principle kinetic NEO model is in close agreement with the edge current density of the reconstructed equilibrium. Furthermore, these results are consistent with recent work showing that the Sauter model largely overestimates the edge bootstrap current at high collisionality.« less

  16. Chromium picolinate inhibits cholesterol-induced stimulation of platelet aggregation in hypercholesterolemic rats.

    PubMed

    Seif, A A

    2015-06-01

    Hypercholesterolemia indirectly increases the risk of myocardial infarction by enhancing platelet aggregation. Chromium has been shown to lower plasma lipids. This study was designed to investigate whether chromium inhibits platelet aggregation under hypercholesterolemic conditions. Albino rats were divided into four groups: control rats fed with a normolipemic diet (NLD group), chromium-supplemented rats fed with NLD (NLD + Cr group), rats fed with a high-fat diet (HF group), and chromium-supplemented rats fed with HF (HF + Cr group). After 10 weeks, blood was collected to determine adenosine diphosphate and collagen-induced platelet aggregation and plasma levels of total cholesterol, triglycerides, high-density lipoprotein cholesterol, apolipoprotein A1, apolipoprotein B, and thromboxane B2. Low-density lipoprotein cholesterol was calculated by Friedewald formula. High-fat diet animals displayed significant elevation of plasma lipids and platelet aggregation which was normalized to control levels by chromium supplementation. Chromium supplementation in normolipemic (NLD + Cr) rats did not produce significant changes in either plasma lipids or platelet activity. Chromium supplementation to hypercholesterolemic rats improves the lipid profile and returns platelet hyperaggregability to control levels. This normalization is mostly due to a reduction in plasma cholesterol level.

  17. First results from the Thomson scattering diagnostic on proto-MPEX.

    PubMed

    Biewer, T M; Meitner, S; Rapp, J; Ray, H; Shaw, G

    2016-11-01

    A Thomson scattering (TS) diagnostic has been successfully implemented on the prototype Material Plasma Exposure eXperiment (Proto-MPEX) at Oak Ridge National Laboratory. The diagnostic collects the light scattered by plasma electrons and spectroscopically resolves the Doppler shift imparted to the light by the velocity of the electrons. The spread in velocities is proportional to the electron temperature, while the total number of photons is proportional to the electron density. TS is a technique used on many devices to measure the electron temperature (T e ) and electron density (n e ) of the plasma. A challenging aspect of the technique is to discriminate the small number of Thomson scattered photons against the large peak of background photons from the high-power laser used to probe the plasma. A variety of methods are used to mitigate the background photons in Proto-MPEX, including Brewster angled windows, viewing dumps, and light baffles. With these methods, first results were measured from argon plasmas in Proto-MPEX, indicating T e ∼ 2 eV and n e ∼ 1 × 10 19 m -3 . The configuration of the Proto-MPEX TS diagnostic will be described and plans for improvement will be given.

  18. First results from the Thomson scattering diagnostic on Proto-MPEX

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Biewer, Theodore M; Meitner, Steven J; Rapp, Juergen

    2016-01-01

    A Thomson scattering diagnostic has been successfully implemented on the prototype Material Plasma Exposure eXperiment (Proto-MPEX) at Oak Ridge National Laboratory. The diagnostic collects the light scattered by plasma electrons and spectroscopically resolves the Doppler shift imparted to the light by the velocity of the electrons. The spread in velocities is proportional to the electron temperature, while the total number of photons is proportional to the electron density. Thomson scattering is a technique used on many devices to measure the electron temperature (Te) and electron density (ne) of the plasma. A challenging aspect of the technique is to discriminate themore » small number of Thomson scattered photons against the large peak of background photons from the high-power laser used to probe the plasma. A variety of methods are used to mitigate the background photons in Proto-MPEX, including Brewster angled windows, viewing dumps, and light baffles. With these methods, first results were measured from Argon plasmas in Proto-MPEX, indicating Te ~ 2 eV and ne ~ 1x1019 m-3. The configuration of the Proto-MPEX Thomson scattering diagnostic will be described and plans for improvement will be given.« less

  19. Perfect relativistic magnetohydrodynamics around black holes in horizon penetrating coordinates

    NASA Astrophysics Data System (ADS)

    Cherubini, Christian; Filippi, Simonetta; Loppini, Alessandro; Moradi, Rahim; Ruffini, Remo; Wang, Yu; Xue, She-Sheng

    2018-03-01

    Plasma accreting processes on black holes represent a central problem for relativistic astrophysics. In this context, here we specifically revisit the classical Ruffini-Wilson work developed for analytically modeling via geodesic equations the accretion of perfect magnetized plasma on a rotating Kerr black hole. Introducing the horizon penetrating coordinates found by Doran 25 years later, we revisit the entire approach studying Maxwell invariants, electric and magnetic fields, volumetric charge density and electromagnetic total energy. We finally discuss the physical implications of this analysis.

  20. Quasistationary Plasma Predator-Prey System of Coupled Turbulence, Drive, and Sheared E × B Flow During High Performance DIII-D Tokamak Discharges [A New, Quasi-stationary Plasma Predator-Prey System of Coupled Turbulence, Drive, and Sheared E × B Flow During High Performance DIII-D Tokamak Discharges

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barada, Kshitish; Rhodes, Terry L.; Burrell, Keith H.

    A new, long-lived limit cycle oscillation (LCO) regime has been observed in the edge of near zero torque high-performance DIII-D tokamak plasma discharges. These LCOs are localized and comprised of density turbulence, gradient drives, and E X B velocity shear damping ( E and B are the local radial electric and total magnetic fields). Density turbulence sequentially acts as a predator (via turbulence transport) of profile gradients and a prey (via shear suppression) to the E X B velocity shear. Reported here for the first time, a unique spatiotemporal variation of the local E X B velocity which is foundmore » to be essential for the existence of this system. The LCO system is quasi-stationary, existing from 3 to 12 plasma energy confinement times (~30 to 900 LCO cycles) limited by hardware constraints. In conclusion, this plasma system appears to contribute strongly to the edge transport in these high-performance and transient-free plasmas as evident from oscillations in transport relevant edge parameters at LCO timescale.« less

  1. Ion Acceleration by Double Layers with Multi-Component Ion Species

    NASA Astrophysics Data System (ADS)

    Good, Timothy; Aguirre, Evan; Scime, Earl; West Virginia University Team

    2017-10-01

    Current-free double layers (CFDL) models have been proposed to explain observations of magnetic field-aligned ion acceleration in plasmas expanding into divergent magnetic field regions. More recently, experimental studies of the Bohm sheath criterion in multiple ion species plasma reveal an equilibration of Bohm speeds at the sheath-presheath boundary for a grounded plate in a multipole-confined filament discharge. We aim to test this ion velocity effect for CFDL acceleration. We report high resolution ion velocity distribution function (IVDF) measurements using laser induced fluorescence downstream of a CFDL in a helicon plasma. Combinations of argon-helium, argon-krypton, and argon-xenon gases are ionized and measurements of argon or xenon IVDFs are investigated to determine whether ion acceleration is enhanced (or diminished) by the presence of lighter (or heavier) ions in the mix. We find that the predominant effect is a reduction of ion acceleration consistent with increased drag arising from increased gas pressure under all conditions, including constant total gas pressure, equal plasma densities of different ions, and very different plasma densities of different ions. These results suggest that the physics responsible for acceleration of multiple ion species in simple sheaths is not responsible for the ion acceleration observed in these expanding plasmas. Department of Physics, Gettysburg College.

  2. Quasistationary Plasma Predator-Prey System of Coupled Turbulence, Drive, and Sheared E × B Flow During High Performance DIII-D Tokamak Discharges [A New, Quasi-stationary Plasma Predator-Prey System of Coupled Turbulence, Drive, and Sheared E × B Flow During High Performance DIII-D Tokamak Discharges

    DOE PAGES

    Barada, Kshitish; Rhodes, Terry L.; Burrell, Keith H.; ...

    2018-03-27

    A new, long-lived limit cycle oscillation (LCO) regime has been observed in the edge of near zero torque high-performance DIII-D tokamak plasma discharges. These LCOs are localized and comprised of density turbulence, gradient drives, and E X B velocity shear damping ( E and B are the local radial electric and total magnetic fields). Density turbulence sequentially acts as a predator (via turbulence transport) of profile gradients and a prey (via shear suppression) to the E X B velocity shear. Reported here for the first time, a unique spatiotemporal variation of the local E X B velocity which is foundmore » to be essential for the existence of this system. The LCO system is quasi-stationary, existing from 3 to 12 plasma energy confinement times (~30 to 900 LCO cycles) limited by hardware constraints. In conclusion, this plasma system appears to contribute strongly to the edge transport in these high-performance and transient-free plasmas as evident from oscillations in transport relevant edge parameters at LCO timescale.« less

  3. Advanced Thomson scattering system for high-flux linear plasma generator.

    PubMed

    van der Meiden, H J; Lof, A R; van den Berg, M A; Brons, S; Donné, A J H; van Eck, H J N; Koelman, P M J; Koppers, W R; Kruijt, O G; Naumenko, N N; Oyevaar, T; Prins, P R; Rapp, J; Scholten, J; Schram, D C; Smeets, P H M; van der Star, G; Tugarinov, S N; Zeijlmans van Emmichoven, P A

    2012-12-01

    An advanced Thomson scattering system has been built for a linear plasma generator for plasma surface interaction studies. The Thomson scattering system is based on a Nd:YAG laser operating at the second harmonic and a detection branch featuring a high etendue (f/3) transmission grating spectrometer equipped with an intensified charged coupled device camera. The system is able to measure electron density (n(e)) and temperature (T(e)) profiles close to the output of the plasma source and, at a distance of 1.25 m, just in front of a target. The detection system enables to measure 50 spatial channels of about 2 mm each, along a laser chord of 95 mm. By summing a total of 30 laser pulses (0.6 J, 10 Hz), an observational error of 3% in n(e) and 6% in T(e) (at n(e) = 9.4 × 10(18) m(-3)) can be obtained. Single pulse Thomson scattering measurements can be performed with the same accuracy for n(e) > 2.8 × 10(20) m(-3). The minimum measurable density and temperature are n(e) < 1 × 10(17) m(-3) and T(e) < 0.07 eV, respectively. In addition, using the Rayleigh peak, superimposed on the Thomson scattered spectrum, the neutral density (n(0)) of the plasma can be measured with an accuracy of 25% (at n(0) = 1 × 10(20) m(-3)). In this report, the performance of the Thomson scattering system will be shown along with unprecedented accurate Thomson-Rayleigh scattering measurements on a low-temperature argon plasma expansion into a low-pressure background.

  4. Low-pressure hydrogen discharge maintenance in a large-size plasma source with localized high radio-frequency power deposition

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Todorov, D.; Shivarova, A., E-mail: ashiva@phys.uni-sofia.bg; Paunska, Ts.

    2015-03-15

    The development of the two-dimensional fluid-plasma model of a low-pressure hydrogen discharge, presented in the study, is regarding description of the plasma maintenance in a discharge vessel with the configuration of the SPIDER source. The SPIDER source, planned for the neutral-beam-injection plasma-heating system of ITER, is with localized high RF power deposition to its eight drivers (cylindrical-coil inductive discharges) and a large-area second chamber, common for all the drivers. The continuity equations for the charged particles (electrons and the three types of positive ions) and for the neutral species (atoms and molecules), their momentum equations, the energy balance equations formore » electrons, atoms and molecules and the Poisson equations are involved in the discharge description. In addition to the local processes in the plasma volume, the surface processes of particle reflection and conversion on the walls as well as for a heat exchange with the walls are included in the model. The analysis of the results stresses on the role of the fluxes (particle and energy fluxes) in the formation of the discharge structure. The conclusion is that the discharge behavior is completely obeyed to non-locality. The latter is displayed by: (i) maximum values of plasma parameters (charged particle densities and temperatures of the neutral species) outside the region of the RF power deposition, (ii) shifted maxima of the electron density and temperature, of the plasma potential and of the electron production, (iii) an electron flux, with a vortex structure, strongly exceeding the total ion flux which gives evidence of a discharge regime of non-ambipolarity and (iv) a spatial distribution of the densities of the neutral species resulting from their fluxes.« less

  5. Advanced control of neutral beam injected power in DIII-D

    DOE PAGES

    Pawley, Carl J.; Crowley, Brendan J.; Pace, David C.; ...

    2017-03-23

    In the DIII-D tokamak, one of the most powerful techniques to control the density, temperature and plasma rotation is by eight independently modulated neutral beam sources with a total power of 20 MW. The rapid modulation requires a high degree of reproducibility and precise control of the ion source plasma and beam acceleration voltage. Recent changes have been made to the controls to provide a new capability to smoothly vary the beam current and beam voltage during a discharge, while maintaining the modulation capability. The ion source plasma inside the arc chamber is controlled through feedback from the Langmuir probesmore » measuring plasma density near the extraction end. To provide the new capability, the plasma control system (PCS) has been enabled to change the Langmuir probe set point and the beam voltage set point in real time. When the PCS varies the Langmuir set point, the plasma density is directly controlled in the arc chamber, thus changing the beam current (perveance) and power going into the tokamak. Alternately, the PCS can sweep the beam voltage set point by 20 kV or more and adjust the Langmuir probe setting to match, keeping the perveance constant and beam divergence at a minimum. This changes the beam power and average neutral particle energy, which changes deposition in the tokamak plasma. The ion separating magnetic field must accurately match the beam voltage to protect the beam line. To do this, the magnet current control accurately tracks the beam voltage set point. In conclusion, these new capabilities allow continuous in-shot variation of neutral beam ion energy to complement« less

  6. Wavefront-sensor-based electron density measurements for laser-plasma accelerators.

    PubMed

    Plateau, G R; Matlis, N H; Geddes, C G R; Gonsalves, A J; Shiraishi, S; Lin, C; van Mourik, R A; Leemans, W P

    2010-03-01

    Characterization of the electron density in laser produced plasmas is presented using direct wavefront analysis of a probe laser beam. The performance of a laser-driven plasma-wakefield accelerator depends on the plasma wavelength and hence on the electron density. Density measurements using a conventional folded-wave interferometer and using a commercial wavefront sensor are compared for different regimes of the laser-plasma accelerator. It is shown that direct wavefront measurements agree with interferometric measurements and, because of the robustness of the compact commercial device, offer greater phase sensitivity and straightforward analysis, improving shot-to-shot plasma density diagnostics.

  7. Wavefront-sensor-based electron density measurements for laser-plasma accelerators

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Plateau, Guillaume; Matlis, Nicholas; Geddes, Cameron

    2010-02-20

    Characterization of the electron density in laser produced plasmas is presented using direct wavefront analysis of a probe laser beam. The performance of a laser-driven plasma-wakefield accelerator depends on the plasma wavelength, hence on the electron density. Density measurements using a conventional folded-wave interferometer and using a commercial wavefront sensor are compared for different regimes of the laser-plasma accelerator. It is shown that direct wavefront measurements agree with interferometric measurements and, because of the robustness of the compact commercial device, have greater phase sensitivity, straightforward analysis, improving shot-to-shot plasma-density diagnostics.

  8. Revealing plasma oscillation in THz spectrum from laser plasma of molecular jet.

    PubMed

    Li, Na; Bai, Ya; Miao, Tianshi; Liu, Peng; Li, Ruxin; Xu, Zhizhan

    2016-10-03

    Contribution of plasma oscillation to the broadband terahertz (THz) emission is revealed by interacting two-color (ω/2ω) laser pulses with a supersonic jet of nitrogen molecules. Temporal and spectral shifts of THz waves are observed as the plasma density varies. The former owes to the changing refractive index of the THz waves, and the latter correlates to the varying plasma frequency. Simulation of considering photocurrents, plasma oscillation and decaying plasma density explains the broadband THz spectrum and the varying THz spectrum. Plasma oscillation only contributes to THz waves at low plasma density owing to negligible plasma absorption. At the longer medium or higher density, the combining effects of plasma oscillation and absorption results in the observed low-frequency broadband THz spectra.

  9. Transportation properties of a high-current magnetically insulated transmission line and dynamics of the electrode plasma

    NASA Astrophysics Data System (ADS)

    Anan'ev, S. S.; Bakshaev, Yu. L.; Bartov, A. V.; Blinov, P. I.; Dan'ko, S. A.; Zhuzhunashvili, A. I.; Kazakov, E. D.; Kalinin, Yu. G.; Kingsep, A. S.; Korolev, V. D.; Mizhiritskii, V. I.; Smirnov, V. P.; Tkachenko, S. I.; Chernenko, A. S.

    2008-07-01

    Results are presented from experimental studies of a section of a magnetically insulated transmission line (MITL) with a current density of up to 500 MA/cm2 and linear current density of up to 7 MA/cm (the parameters close to those in a fast-Z-pinch-driven fusion reactor projected at Sandia Laboratories). The experiments were performed in the S-300 facility (3 MA, 0.15 Ω, 100 ns). At high linear current densities, the surface of the ohmically heated MITL electrode can explode and a plasma layer can form near the electrode surface. As a result, the MITL can lose its transmission properties due to the shunting of the vacuum gap by the plasma produced. In this series of experiments, the dynamics of the electrode plasma and the dependence of the transmission properties of the MITL on the material and cleanness of the electrode surface were studied. It is shown experimentally that, when the current with a linear density of up to 7 MA/cm begins to flow along a model MITL, the input and output currents differ by less than 10% over a time interval of up to 230 ns for nickel electrodes and up to 350 ns for a line with a gold central electrode. No effect of the oil film present on the electrode surface on the loss of the transmission properties of the line was observed. It is also shown that electron losses insignificantly contribute to the total current balance. The experimental results are compared with calculations of the electrode explosion and the subsequent expansion of the plasma layer. A conclusion is made that the life-time of the model MITL satisfies the requirements imposed on the transmission lines intended for use in the projected thermonuclear reactor.

  10. Investigations in the ionosphere by means of Kosmos 378. N(h) profiles and the temperature of the F region according to ground-based and satellite measurements above Khabarovsk

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mirmovich, E.G.; Shapiro, B.S.

    1975-01-01

    Simultaneous satellite measurements of electron density N/sub s/ and temperature (T/sub e/)/sub s/ at a height h/sub s/ above an observatory and ground-based observations are used to compute the total vertical electron density profiles N(h) and estimate the temperature of the ionospheric plasma. Four close time intervals after sunset were selected for analysis.

  11. High-fat diet and chronic stress reduce central pressor and tachycardic effects of apelin in Sprague-Dawley rats.

    PubMed

    Cudnoch-Jedrzejewska, Agnieszka; Gomolka, Ryszard; Szczepanska-Sadowska, Ewa; Czarzasta, Katarzyna; Wrzesien, Robert; Koperski, Lukasz; Puchalska, Liana; Wsol, Agnieszka

    2015-01-01

    Central application of apelin elevates blood pressure and influences neuroendocrine responses to stress and food consumption. However, it is not known whether the central cardiovascular effects of apelin depend also on caloric intake or chronic stress. The purpose of the present study was to determine the effects of intracerebroventricular administration of apelin on blood pressure (mean arterial blood pressure) and heart rate in conscious Sprague-Dawley rats consuming either a normal-fat diet (NFD) or high-fat diet (HFD) for 12 weeks. During the last 4 weeks of the food regime, the rats were exposed (NFDS and HFDS groups) or not exposed (NFDNS and HFDNS groups) to chronic stress. Each group was divided into two subgroups receiving intracerebroventricular infusions of either vehicle or apelin. Apelin elicited significant increase of mean arterial blood pressure and heart rate in the NFDNS rats. This effect was abolished in the HFDNS, HFDS and NFDS groups. HFD resulted in a significant elevation of blood concentrations of total cholesterol, triglycerides glucose and insulin. Chronic stress reduced plasma concentration of total and high-density lipoprotein cholesterol, and increased plasma corticosterone concentration and APJ receptor mRNA expression in the hypothalamus, whereas a combination of a HFD with chronic stress resulted in the elevation of plasma triglycerides, total cholesterol and low-density lipoprotein cholesterol, and in increased plasma corticosterone concentration, apelin concentration and APJ receptor mRNA expression in the hypothalamus. It is concluded that a HFD and chronic stress result in significant suppression of the central pressor action of apelin, and cause significant though not unidirectional changes of metabolic and endocrine parameters. © 2014 Wiley Publishing Asia Pty Ltd.

  12. High-efficiency acceleration in the laser wakefield by a linearly increasing plasma density

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dong, Kegong; Wu, Yuchi; Zhu, Bin

    The acceleration length and the peak energy of the electron beam are limited by the dephasing effect in the laser wakefield acceleration with uniform plasma density. Based on 2D-3V particle in cell simulations, the effects of a linearly increasing plasma density on the electron acceleration are investigated broadly. Comparing with the uniform plasma density, because of the prolongation of the acceleration length and the gradually increasing accelerating field due to the increasing plasma density, the electron beam energy is twice higher in moderate nonlinear wakefield regime. Because of the lower plasma density, the linearly increasing plasma density can also avoidmore » the dark current caused by additional injection. At the optimal acceleration length, the electron energy can be increased from 350 MeV (uniform) to 760 MeV (linearly increasing) with the energy spread of 1.8%, the beam duration is 5 fs and the beam waist is 1.25 μm. This linearly increasing plasma density distribution can be achieved by a capillary with special gas-filled structure, and is much more suitable for experiment.« less

  13. Preliminary scaling laws for plasma current, ion kinetic temperature, and plasma number density in the NASA Lewis bumpy torus plasma

    NASA Technical Reports Server (NTRS)

    Roth, J. R.

    1976-01-01

    Parametric variation of independent variables which may affect the characteristics of bumpy torus plasma have identified those which have a significant effect on the plasma current, ion kinetic temperature, and plasma number density, and those which do not. Empirical power law correlations of the plasma current, and the ion kinetic temperature and number density were obtained as functions of potential applied to the midplane electrode rings, the background neutral gas pressure, and the magnetic field strength. Additional parameters studied included the type of gas, the polarity of the midplane electrode rings, the mode of plasma operation, and the method of measuring the plasma number density. No significant departures from the scaling laws appear to occur at the highest ion kinetic temperatures or number densities obtained to date.

  14. Transverse ion energization and low-frequency plasma waves in the mid-altitude auroral zone - A case study

    NASA Technical Reports Server (NTRS)

    Peterson, W. K.; Shelley, E. G.; Boardsen, S. A.; Gurnett, D. A.; Ledley, B. G.; Sugiura, M.; Moore, T. E.

    1988-01-01

    Evidence of transverse ion energization at altitudes of several earth radii in the auroral zone was reexamined using several hundred hours of high-sensitivity and high-resolution plasma data obtained by the Dynamics Explorer 1 satellite. The data on particle environment encountered at midaltitudes in the auroral zone disclosed rapid variations in the values of total density, thermal structure, and composition of the plasma in the interval measured; the modes of low-frequency plasma waves also varied rapidly. It was not possible to unambiguously identify in these data particle and wave signature of local transverse ion energization; however, many intervals were found where local transverse ion heating was consistent with the observations.

  15. Contemporary trends in dyslipidemia in the Framingham Heart Study

    USDA-ARS?s Scientific Manuscript database

    Recent cross-sectional population studies in the United States have shown an increase in obesity, a decrease in cholesterol values, but no changes in levels of high-density lipoprotein cholesterol (HDL-C) or triglycerides (TG). Plasma total cholesterol, HDL-C, and TG levels, measured by the same met...

  16. Effects of dietary creatine supplementation on systemic microvascular density and reactivity in healthy young adults.

    PubMed

    Moraes, Roger de; Van Bavel, Diogo; Moraes, Beatriz Serpa de; Tibiriçá, Eduardo

    2014-12-15

    Dietary creatine supplementation (CrS) is a practice commonly adopted by physically active individuals. However, the effects of CrS on systemic microvascular reactivity and density have never been reported. Additionally, CrS is able to influence blood levels of homocysteine, resulting in presumed effects on vascular endothelial function. Thus, we investigated the effects of CrS on the systemic microcirculation and on homocysteine levels in healthy young individuals. This open-label study was performed on a group of 40 healthy male, moderately physically active subjects aged 27.7 ± 13.4 years who received one week of CrS at a dose of 20 g/day of commercially available micronized creatine monohydrate. Laser speckle contrast imaging was used in the evaluation of cutaneous microvascular reactivity, and intra-vital video microscopy was used to evaluate skin capillary density and reactivity, before and after CrS. CrS did not alter plasma levels of homocysteine, although CrS increased creatinine (p = 0.0001) and decreased uric acid (p = 0.0004) plasma levels. Significant changes in total cholesterol (p = 0.0486) and LDL-cholesterol (p = 0.0027) were also observed along with a reduction in plasma levels of T3 (p = 0.0074) and an increase in T4 levels (p = 0.0003). Skin functional capillary density (p = 0.0496) and capillary recruitment during post-occlusive reactive hyperemia (p = 0.0043) increased after CrS. Increases in cutaneous microvascular vasodilation induced by post-occlusive reactive hyperemia (p = 0.0078) were also observed. Oral supplementation with creatine in healthy, moderately physically active young adults improves systemic endothelial-dependent microvascular reactivity and increases skin capillary density and recruitment. These effects are not concurrent with changes in plasma homocysteine levels.

  17. Creating Hybrid Plasmas With Off-Axis ECCD for Radiating Divertor Studies in DIII-D

    NASA Astrophysics Data System (ADS)

    Petty, C. C.; Ferron, J. R.; Luce, T. C.; Osborne, T. H.; Petrie, T. W.; Turco, F.; Holcomb, C. T.; Thome, K. E.

    2017-10-01

    A long duration, high density, high power hybrid scenario has been developed for use in radiative divertor studies in DIII-D. Using 11.2 MW of co-NBI power and 3.4 MW of ECCD, with a total injected energy of up to 56 MJ, high performance hybrid plasmas with βN = 3.7 and H98y2 = 1.5 were created. The hybrid plasmas were fully non-inductive at densities of n 4.2 ×1019 m-3 with central ECCD, but the EC deposition needed to be moved to ρ = 0.45 to avoid the right-hand cutoff when the density was raised to n 5.8 ×1019 m-3 for radiative divertor studies. Although moving the EC deposition to ρ = 0.45 had the effect of dropping τE by 10%, the energy confinement time increased with higher density like τE n0.4, allowing high beta to be maintained. While the plasma current profile displays the usual self-organizing properties of hybrids - an anomalously broad profile with qmin >1 - local current drive can still have a measurable effect on stability, either positively or negatively. For example, hybrid discharges with radial ECH deposited at ρ = 0.45 proved to be more robustly stable to n = 1 modes (can be either a 1/1 or 2/1 mode) than similar discharges with co-ECCD at the same location. Interestingly, the large 1/1 mode had almost no effect on energy confinement but strongly degraded particle confinement; thus this mode needed to be suppressed to achieve the high pedestal densities required for radiative divertor studies. Work supported by USDOE under DE-FC02-04ER54698.

  18. Plasma selenium, zinc, copper and lipid levels in postmenopausal Turkish women and their relation with osteoporosis.

    PubMed

    Arikan, Deniz Cemgil; Coskun, Ayhan; Ozer, Ali; Kilinc, Metin; Atalay, Filiz; Arikan, Tugba

    2011-12-01

    It has been shown that the trace elements and lipids play role in the growth, development and maintenance of bones. We aimed to investigate serum selenium (Se), zinc (Zn), copper (Cu) and lipid (total cholesterol, triglyceride (TG), high density lipoprotein-cholesterol, low-density lipoprotein-cholesterol) levels in postmenopausal women with osteoporosis, osteopenia and in healthy controls, and to determine the relationship between Se, Zn, Cu and lipid parameters and bone mineral density (BMD). The study included 107 postmenopausal women; 35 healthy (group 1), 37 osteopenic (group 2) and 35 osteoporotic (group 3). The women in all three groups were carefully matched for body mass index (BMI). Serum concentrations of Se, Zn and Cu were measured by atomic absorption spectrophotometry. Plasma Se, Cu, Zn and lipid levels were similar in all groups (p > 0.05). When we combined the women in each of the three groups, and considered them as one group (n = 107) we found a positive correlation between BMI and lumbar vertebra BMD, femur neck BMD, femur total BMD; a positive correlation between TG and femur neck BMD, femur total BMD; a positive correlation between Zn and lumbar vertebra BMD (total T score) (p < 0.05). There was no correlation between Se, Cu, Zn, P and lipid parameters (p > 0.05). Although BMI has a positive effect on BMD, trace elements and lipids, except Zn and TG, did not directly and correlatively influence BMD. Further studies are needed to clarify the role and relationship of trace elements and lipid parameters in postmenopausal osteoporosis.

  19. Design of a novel high efficiency antenna for helicon plasma sources

    NASA Astrophysics Data System (ADS)

    Fazelpour, S.; Chakhmachi, A.; Iraji, D.

    2018-06-01

    A new configuration for an antenna, which increases the absorption power and plasma density, is proposed for helicon plasma sources. The influence of the electromagnetic wave pattern symmetry on the plasma density and absorption power in a helicon plasma source with a common antenna (Nagoya) is analysed by using the standard COMSOL Multiphysics 5.3 software. In contrast to the theoretical model prediction, the electromagnetic wave does not represent a symmetric pattern for the common Nagoya antenna. In this work, a new configuration for an antenna is proposed which refines the asymmetries of the wave pattern in helicon plasma sources. The plasma parameters such as plasma density and absorption rate for a common Nagoya antenna and our proposed antenna under the same conditions are studied using simulations. In addition, the plasma density of seven operational helicon plasma source devices, having a common Nagoya antenna, is compared with the simulation results of our proposed antenna and the common Nagoya antenna. The simulation results show that the density of the plasma, which is produced by using our proposed antenna, is approximately twice in comparison to the plasma density produced by using the common Nagoya antenna. In fact, the simulation results indicate that the electric and magnetic fields symmetry of the helicon wave plays a vital role in increasing wave-particle coupling. As a result, wave-particle energy exchange and the plasma density of helicon plasma sources will be increased.

  20. Scaling high-order harmonic generation from laser-solid interactions to ultrahigh intensity.

    PubMed

    Dollar, F; Cummings, P; Chvykov, V; Willingale, L; Vargas, M; Yanovsky, V; Zulick, C; Maksimchuk, A; Thomas, A G R; Krushelnick, K

    2013-04-26

    Coherent x-ray beams with a subfemtosecond (<10(-15)  s) pulse duration will enable measurements of fundamental atomic processes in a completely new regime. High-order harmonic generation (HOHG) using short pulse (<100  fs) infrared lasers focused to intensities surpassing 10(18)  W cm(-2) onto a solid density plasma is a promising means of generating such short pulses. Critical to the relativistic oscillating mirror mechanism is the steepness of the plasma density gradient at the reflection point, characterized by a scale length, which can strongly influence the harmonic generation mechanism. It is shown that for intensities in excess of 10(21)  W cm(-2) an optimum density ramp scale length exists that balances an increase in efficiency with a growth of parametric plasma wave instabilities. We show that for these higher intensities the optimal scale length is c/ω0, for which a variety of HOHG properties are optimized, including total conversion efficiency, HOHG divergence, and their power law scaling. Particle-in-cell simulations show striking evidence of the HOHG loss mechanism through parametric instabilities and relativistic self-phase modulation, which affect the produced spectra and conversion efficiency.

  1. Extension of electron cyclotron heating at ASDEX Upgrade with respect to high density operation

    NASA Astrophysics Data System (ADS)

    Schubert, Martin; Stober, Jörg; Herrmann, Albrecht; Kasparek, Walter; Leuterer, Fritz; Monaco, Francesco; Petzold, Bernhard; Plaum, Burkhard; Vorbrugg, Stefan; Wagner, Dietmar; Zohm, Hartmut

    2017-10-01

    The ASDEX Upgrade electron cyclotron resonance heating operates at 105 GHz and 140 GHz with flexible launching geometry and polarization. In 2016 four Gyrotrons with 10 sec pulse length and output power close to 1 MW per unit were available. The system is presently being extended to eight similar units in total. High heating power and high plasma density operation will be a part of the future ASDEX Upgrade experiment program. For the electron cyclotron resonance heating, an O-2 mode scheme is proposed, which is compatible with the expected high plasma densities. It may, however, suffer from incomplete single-pass absorption. The situation can be improved significantly by installing holographic mirrors on the inner column, which allow for a second pass of the unabsorbed fraction of the millimetre wave beam. Since the beam path in the plasma is subject to refraction, the beam position on the holographic mirror has to be controlled. Thermocouples built into the mirror surface are used for this purpose. As a protective measure, the tiles of the heat shield on the inner column were modified in order to increase the shielding against unabsorbed millimetre wave power.

  2. VASIMR VX-200 thruster throttling optimization from 30 to 200 kW

    NASA Astrophysics Data System (ADS)

    Squire, Jared; Olsen, Chris; Chang-Diaz, Franklin; Longmier, Benjamin; Ballenger, Maxwell; Carter, Mark; Glover, Tim; McCaskill, Greg

    2012-10-01

    The VASIMR^ VX-200 experimental plasma thruster incorporates a 40 kW helicon plasma source with a 180 kW Ion Cyclotron Heating (ICH) acceleration stage integrated in a superconducting magnet. Argon propellant mass flow is injected up to 140 mg/s. Rapid plasma start up (< 100 ms) and high pumping speed (> 10^5 liters/s) in a 150 m^3 vacuum chamber achieve performance measurements with the charge exchange mean-free-path greater than 1 m in the background neutral gas (pressure < 10-5 Torr). The thruster efficiency at 200 kW total power is 72 ± 9%, the ratio of effective jet power to input RF power, with an Isp = 4900 ± 300 seconds (flow velocity of 49 km/s), and an ion flux of 1.7 ± 0.1 x 10^21/s. The thrust increases steadily with power to 5.8 ± 0.4 N until the power is maximized and there is no indication of saturation. The plasma density near the device exit exceeds 10^18 m-3 with a power density over 5 MW/m^2. An extensive study of thruster performance, efficiency and thrust-to-power ratio, as a function of Ar propellant flow rate and ICH-to-helicon RF power ratio has been carried out over a total power range of 30 to 200 kW. Optimized throttling set points are determined. The experimental configuration and results of this study are presented.

  3. Preliminary scaling laws for plasma current, ion kinetic temperature, and plasma number density in the NASA Lewis Bumpy Torus plasma

    NASA Technical Reports Server (NTRS)

    Roth, J. R.

    1976-01-01

    Parametric variation of independent variables which may affect the characteristics of the NASA Lewis Bumpy Torus plasma have identified those which have a significant effect on the plasma current, ion kinetic temperature, and plasma number density, and those which do not. Empirical power-law correlations of the plasma current, and the ion kinetic temperature and number density were obtained as functions of the potential applied to the midplane electrode rings, the background neutral gas pressure, and the magnetic field strength. Additional parameters studied include the type of gas, the polarity of the midplane electrode rings (and hence the direction of the radial electric field), the mode of plasma operation, and the method of measuring the plasma number density. No significant departures from the scaling laws appear to occur at the highest ion kinetic temperatures or number densities obtained to date.

  4. Nonlinear Associations between Plasma Cholesterol Levels and Neuropsychological Function

    PubMed Central

    Wendell, Carrington R.; Zonderman, Alan B.; Katzel, Leslie I.; Rosenberger, William F.; Plamadeala, Victoria V.; Hosey, Megan M.; Waldstein, Shari R.

    2016-01-01

    Objective Although both high and low levels of total and low-density lipoprotein (LDL) cholesterol have been associated with poor neuropsychological function, little research has examined nonlinear effects. We examined quadratic relations of cholesterol to performance on a comprehensive neuropsychological battery. Method Participants were 190 older adults (53% men, ages 54–83) free of major medical, neurologic, and psychiatric disease. Measures of fasting plasma total and high-density lipoprotein (HDL) cholesterol were assayed, and LDL cholesterol was calculated. Participants completed neuropsychological measures of attention, executive function, memory, visuospatial judgment, and manual speed/dexterity. Multiple regression analyses examined cholesterol levels as quadratic predictors of each measure of cognitive performance, with age (dichotomized as <70 vs. 70+) as an effect modifier. Results A significant quadratic effect of total cholesterol2 × age was identified for Logical Memory II (b=−.0013, p=.039), such that the 70+ group performed best at high and low levels of total cholesterol than at mid-range total cholesterol (U-shaped), and the <70 group performed worse at high and low levels of total cholesterol than at mid-range total cholesterol (inverted U-shape). Similarly, significant U- and J-shaped effects of LDL cholesterol2 × age were identified for Visual Reproduction II (b=−.0020, p=.026) and log of Trails B (b=.0001, p=.044). Quadratic associations between HDL cholesterol and cognitive performance were nonsignificant. Conclusions Results indicate differential associations between cholesterol and neuropsychological function across different ages and domains of function. High and low total and LDL cholesterol may confer both risk and benefit for suboptimal cognitive function at different ages. PMID:27280580

  5. Directional power absorption in helicon plasma sources excited by a half-helix antenna

    NASA Astrophysics Data System (ADS)

    Afsharmanesh, Mohsen; Habibi, Morteza

    2017-10-01

    This paper deals with the investigation of the power absorption in helicon plasma excited through a half-helix antenna driven at 13.56 {{MHz}}. The simulations were carried out by means of a code, HELIC. They were carried out by taking into account different inhomogeneous radial density profiles and for a wide range of plasma densities, from {10}11 {{{cm}}}-3 to {10}13 {{{cm}}}-3. The magnetic field was 200, 400, 600 and 1000 {{G}}. A three-parameter function was used for generating various density profiles with different volume gradients, edge gradients and density widths. The density profile had a large effect on the efficient Trivelpiece-Gould (TG) and helicon mode excitation and antenna coupling to the plasma. The fraction of power deposition via the TG mode was extremely dependent on the plasma density near the plasma boundary. Interestingly, the obtained efficient parallel helicon wavelength was close to the anticipated value for Gaussian radial density profile. Power deposition was considerably asymmetric when the \\tfrac{n}{{B}0} ratio was more than a specific value for a determined density width. The longitudinal power absorption was symmetric at approximately {n}0={10}11 {{{cm}}}-3, irrespective of the magnetic field supposed. The asymmetry became more pronounced when the plasma density was {10}12 {{{cm}}}-3. The ratio of density width to the magnetic field was an important parameter in the power coupling. At high magnetic fields, the maximum of the power absorption was reached at higher plasma density widths. There was at least one combination of the plasma density, magnetic field and density width for which the RF power deposition at both side of the tube reached its maximum value.

  6. Regimes of enhanced electromagnetic emission in beam-plasma interactions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Timofeev, I. V.; Annenkov, V. V.; Arzhannikov, A. V.

    2015-11-15

    The ways to improve the efficiency of electromagnetic waves generation in laboratory experiments with high-current relativistic electron beams injected into a magnetized plasma are discussed. It is known that such a beam can lose, in a plasma, a significant part of its energy by exciting a high level of turbulence and heating plasma electrons. Beam-excited plasma oscillations may simultaneously participate in nonlinear processes resulting in a fundamental and second harmonic emissions. It is obvious, however, that in the developed plasma turbulence the role of these emissions in the total energy balance is always negligible. In this paper, we investigate whethermore » electromagnetic radiation generated in the beam-plasma system can be sufficiently enhanced by the direct linear conversion of resonant beam-driven modes into electromagnetic ones on preformed regular inhomogeneities of plasma density. Due to the high power of relativistic electron beams, the mechanism discussed may become the basis for the generator of powerful sub-terahertz radiation.« less

  7. Neutral and Plasma Sources in the Saturn's Magnetosphere

    NASA Astrophysics Data System (ADS)

    Jurac, S.; Johnson, R. E.

    1999-05-01

    The heavy ion plasma in Saturnian inner magnetosphere is derived from the icy satellites and ring particles imbedded in the plasma. Recent Hubble Space Telescope measurements of the densities of neutral OH molecules which co-exist with and are precursors of the plasma ions have constrained models for the plasma sources. Richardson et al (1998) considered all existing HST observations and derived water-like neutral densities and estimated required sources to maintain equilibrium. Their neutral densities show maximum close to Enceladus (where the E-ring density peaks) and their total neutral source rate needed to maintain neutrals in steady state is for an order of magnitude larger than source rate given by Shi et al (1995). We model the sputtering of water-ice using the recently developed Monte-Carlo collisional transport code, and calculate neutral supply rates from sputtering of Enceladus and the E-ring. This collisional code, used previously to evaluate sputtering from the interstellar grains (Jurac et al, 1998) is modified to include electronic processes relevant to water-ice sputtering, and then applied to the E-ring grains. It is shown that the grain erosion rate increases substantially when the ion penetration depth becomes comparable to the grain radius. The sputtering and collection rates for plasma ions and neutrals are evaluated and it is shown that the E-ring might be the dominant source of water-like neutrals in the Saturnian magnetosphere. We also describe competition between grain growth and erosion and discuss implications to the existing E-ring evolutionary models. References: Jurac S., R. E. Johnson, B. Donn; Astroph. J. 503, 247, 1998 Richardson, J. D., A. Eviatar, M. A. McGrath, V. M. Vasyliunas; J. Geophys. Res., 103, 20245, 1998 Shi, M., R.A. Baragiola, D.E. Grosjean, R.E. Johnson, S. Jurac and J. Schou; J. Geophys. Res., 100, 26387, 1995.

  8. Plasma non-uniformity in a symmetric radiofrequency capacitively-coupled reactor with dielectric side-wall: a two dimensional particle-in-cell/Monte Carlo collision simulation

    NASA Astrophysics Data System (ADS)

    Liu, Yue; Booth, Jean-Paul; Chabert, Pascal

    2018-02-01

    A Cartesian-coordinate two-dimensional electrostatic particle-in-cell/Monte Carlo collision (PIC/MCC) plasma simulation code is presented, including a new treatment of charge balance at dielectric boundaries. It is used to simulate an Ar plasma in a symmetric radiofrequency capacitively-coupled parallel-plate reactor with a thick (3.5 cm) dielectric side-wall. The reactor size (12 cm electrode width, 2.5 cm electrode spacing) and frequency (15 MHz) are such that electromagnetic effects can be ignored. The dielectric side-wall effectively shields the plasma from the enhanced electric field at the powered-grounded electrode junction, which has previously been shown to produce locally enhanced plasma density (Dalvie et al 1993 Appl. Phys. Lett. 62 3207-9 Overzet and Hopkins 1993 Appl. Phys. Lett. 63 2484-6 Boeuf and Pitchford 1995 Phys. Rev. E 51 1376-90). Nevertheless, enhanced electron heating is observed in a region adjacent to the dielectric boundary, leading to maxima in ionization rate, plasma density and ion flux to the electrodes in this region, and not at the reactor centre as would otherwise be expected. The axially-integrated electron power deposition peaks closer to the dielectric edge than the electron density. The electron heating components are derived from the PIC/MCC simulations and show that this enhanced electron heating results from increased Ohmic heating in the axial direction as the electron density decreases towards the side-wall. We investigated the validity of different analytical formulas to estimate the Ohmic heating by comparing them to the PIC results. The widespread assumption that a time-averaged momentum transfer frequency, v m , can be used to estimate the momentum change can cause large errors, since it neglects both phase and amplitude information. Furthermore, the classical relationship between the total electron current and the electric field must be used with caution, particularly close to the dielectric edge where the (neglected) pressure gradient term becomes significant.

  9. Spectrocopic measurements of water vapor plasmas at high resolution: The optical transition probabilities for OH (A 2 Sigma - X 2 Pi)

    NASA Technical Reports Server (NTRS)

    Klein, L.

    1972-01-01

    Emission and absorption spectra of water vapor plasmas generated in a wall-stabilized arc at atmospheric pressure and 4 current, and at 0.03 atm and 15 to 50 A, were measured at high spatial and spectral resolution. The gas temperature was determined from the shape of Doppler-broadened rotational lines of OH. The observed nonequilibrium population distributions over the energy levels of atoms are interpreted in terms of a theoretical state model for diffusion-controlled arc plasmas. Excellent correlation is achieved between measured and predicted occupation of hydrogen energy levels. It is shown that the population distribution over the nonpredissociating rotational-vibrational levels of the A 2 Sigma state of OH is close to an equilibrium distribution at the gas temperature, although the total density of this state is much higher than its equilibrium density. The reduced intensities of the rotational lines originating in these levels yielded Boltzmann plots that were strictly linear.

  10. Protection by scoparone against the alterations of plasma lipoproteins, vascular morphology and vascular reactivity in hyperlipidaemic diabetic rabbit.

    PubMed

    Huang, H C; Weng, Y I; Lee, C R; Jan, T R; Chen, Y L; Lee, Y T

    1993-12-01

    1. The in vivo pharmacological effects of scoparone (6,7-dimethoxycoumarin) in a hyperlipidaemic diabetic rabbit model were investigated. 2. Three groups of rabbits were studied: (1) normal, (2) hyperlipidaemic and diabetic-untreated and (3) hyperlipidaemic and diabetic-scoparone treated. The hyperlipidaemic diabetic rabbits were fed with 1% cholesterol and treated with alloxan, a diabetogenic agent. The plasma levels of total cholesterol, total triglyceride, very low-density lipoprotein (VLDL) cholesterol, low density lipoprotein (LDL) cholesterol and high-density lipoprotein (HDL) cholesterol were markedly increased as soon as the rabbit became diabetic at the second week. Scoparone-treatment (5 mg kg-1 day-1, s.c.) significantly reduced the plasma lipid and lipoprotein cholesterol levels of the hyperlipidaemic diabetic rabbit to 73.3% of total cholesterol, 48.3% of total triglyceride, 66.0% of VLDL cholesterol, 55.7% of LDL cholesterol and 79.5% of HDL cholesterol. 3. Six weeks after cholesterol-feeding, the aortic arch and thoracic aorta were dissected for morphological and functional studies. In vascular rings from the untreated hyperlipidaemic diabetic rabbit, there was intimal thickening with accumulation of fatty streaks, foam cells and migration of smooth muscle cells to the intima. In the rabbits treated with scoparone, there were fewer pathological morphology changes found in vascular segments than in the untreated hyperlipidaemic diabetic rabbits. 4. In the vascular reactivity experiments, the phenylephrine-induced contraction and nitroprusside induced dilatation did not differ significantly among the three rabbit groups, except that the contraction was enhanced in the thoracic aorta of hyperlipidaemic diabetic rabbits either untreated or treated withscoparone, as compared to the normal group, and the sensitivity to nitroprusside was increased in the thoracic aorta of the scoparone-treated group as compared to the untreated group.5. The endothelium-dependent dilatation induced by acetylcholine was significantly attenuated in both the aortic arch and thoracic aorta from the hyperlipidaemic diabetic rabbits as compared to the normal rabbits. This attenuation was partially prevented, when scoparone (5 mg kg-1) was administered daily.6. These results suggest that scoparone protects against some alterations of plasma lipoproteins,vascular morphology and vascular reactivity in the hyperlipidaemic diabetic rabbit. These protective effects of scoparone may be partly related to its free radical scavenging property.

  11. Plasma ignition and steady state simulations of the Linac4 H- ion source

    NASA Astrophysics Data System (ADS)

    Mattei, S.; Ohta, M.; Yasumoto, M.; Hatayama, A.; Lettry, J.; Grudiev, A.

    2014-02-01

    The RF heating of the plasma in the Linac4 H- ion source has been simulated using a particle-in-cell Monte Carlo collision method. This model is applied to investigate the plasma formation starting from an initial low electron density of 1012 m-3 and its stabilization at 1018 m-3. The plasma discharge at low electron density is driven by the capacitive coupling with the electric field generated by the antenna, and as the electron density increases the capacitive electric field is shielded by the plasma and induction drives the plasma heating process. Plasma properties such as e-/ion densities and energies, sheath formation, and shielding effect are presented and provide insight to the plasma properties of the hydrogen plasma.

  12. Study of the protective effect of ascorbic acid against the toxicity of stannous chloride on oxidative damage, antioxidant enzymes and biochemical parameters in rabbits.

    PubMed

    Yousef, M I; Awad, T I; Elhag, F A; Khaled, F A

    2007-06-25

    Stannous chloride (SnCl2) is a reducing chemical agent used in several man-made products. SnCl2 can generate reactive oxygen species (ROS). Therefore, the present study has been carried out to investigate the antioxidant action of l-ascorbic acid (AA) in minimizing SnCl2 toxicity on lipid peroxidation, antioxidant enzyme, and biochemical parameters in male New Zealand white rabbits. Animals were assigned to one of four treatment groups: 0mg AA and 0mg SnCl2/kg BW (control); 40 mg AA/kg BW; 20mg SnCl2/kg BW; 20mg SnCl2 plus 40 mg AA/kg BW. Rabbits were orally administered the respective doses every other day for 12 weeks. Results obtained showed that SnCl2 significantly (P<0.05) induced thiobarbituric acid-reactive substances (TBARS; the marker of lipid peroxidation) in plasma, while the activities of glutathione S-transferase (GST), superoxide dismutase (SOD) and catalase (CAT), and the level of sulfhydryl groups (SH-group) were decreased (P<0.05) in blood plasma. Aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (AlP), acid phosphatase (AcP) and lactate dehydrogenase (LDH) activities were decreased (P<0.05). Stannous chloride significantly (P<0.05) increased the levels of plasma total lipid (TL), cholesterol, triglyceride (TG), low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL), glucose, urea and total bilirubin. On the other hand, the level of plasma high-density lipoprotein (HDL), total protein (TP), albumin (A) and globulin (G) were significantly (P<0.05) decreased. Ascorbic acid alone significantly decreased the levels of TBARS, lipids and urea, and increased the activities of GST, SOD and CAT, and the levels of SH-group and proteins. While the rest of the tested parameters were not affected. Also, the presence of AA with SnCl2 alleviated its harmful effects on most of the tested parameters. Therefore, the present results revealed that treatment with AA could minimize the toxic effects of stannous chloride.

  13. Canonical angular momentum compression near the Brillouin limit

    NASA Astrophysics Data System (ADS)

    Jeong, E.; Gilson, E.; Fajans, J.

    2000-10-01

    Near the Brillouin limit, the angular momentum of a trapped, T=0, pure-electron plasma approaches zero. If the plasma expands axially, its density would appear to drop. However, the plasma's canonical angular momentum is not changed by an axial expansion, so the plasma must stay near the Brillouin limit; thus the plasma's density cannot change when it is expanded. The only way for the plasma density to remain constant as the plasma length increases is for the plasma radius to decrease. Dynamically, this decrease is caused by the polarization drift induced by a small decrease in the density. In this poster we present preliminary experimental evidence demonstrating this radial compression. This work was supported by the ONR.

  14. Effect of the combination of methyltestosterone and esterified estrogens compared with esterified estrogens alone on apolipoprotein CIII and other apolipoproteins in very low density, low density, and high density lipoproteins in surgically postmenopausal women.

    PubMed

    Chiuve, Stephanie E; Martin, Lisa A; Campos, Hannia; Sacks, Frank M

    2004-05-01

    Androgens are known to lower plasma triglycerides, an independent risk factor for coronary heart disease (CHD). Triglycerides are carried in plasma on very low density (VLDL) and low density (LDL) lipoprotein particles. Apolipoprotein CIII (apoCIII), a strong predictor of CHD, impairs the metabolism of VLDL and LDL, contributing to increased triglycerides. The objective of this study was to assess the effect of oral methyltestosterone (2.5 mg/d), added to esterified estrogens (1.25 mg/d), on concentrations of apolipoproteins and lipoproteins, specifically those containing apoCIII, compared with esterified estrogens alone in surgically postmenopausal women. The women in the methyltestosterone plus esterified estrogen group had significant decreases in total triglycerides, apoCI, apoCII, apoCIII, apoE, and high density lipoprotein (HDL) cholesterol compared with those in the esterified estrogen group. The decreases in apoCIII concentrations occurred in VLDL (62%; P = 0.02), LDL (35%; P = 0.001), and HDL (17%; P < 0.0001). There were also decreases in cholesterol and triglycerides concentrations of apoCIII containing LDL, and apoCI concentration of apoCIII containing VLDL. There was no effect on VLDL and LDL particles that did not contain apoCIII or on apoB concentrations. In conclusion, methyltestosterone, when administered to surgically postmenopausal women taking esterified estrogen, has a selective effect to reduce the apoCIII concentration in VLDL and LDL, a predictor of CHD. Methyltestosterone may lower plasma triglycerides through a reduction in apoCIII.

  15. X-ray Thomson scattering measurements of temperature and density from multi-shocked CH capsules

    DOE PAGES

    Fletcher, L. B.; Glenzer, S. H.; Kritcher, A.; ...

    2013-05-24

    Proof-of-principle measurements of the electron densities, temperatures, and ionization states of spherically compressed multi-shocked CH (polystyrene) capsules have been achieved using spectrally resolved x-ray Thomson scattering. A total energy of 13.5 kJ incident on target is used to compress a 70 μm thick CH shell above solid-mass density using three coalescing shocks. Separately, a laser-produced zinc He-α x-ray source at 9 keV delayed 200 ps-800 ps after maximum compression is used to probe the plasma in the non-collective scattering regime. The data show that x-ray Thomson scattering enables a complete description of the time-dependent hydrodynamic evolution of shock-compressed CH capsules,more » with a maximum measured density of ρ > 6 g cm –3. Additionally, the results demonstrate that accurate measurements of x-ray scattering from bound-free transitions in the CH plasma demonstrate strong evidence that continuum lowering is the primary ionization mechanism of carbon L-shell electrons.« less

  16. High Current, High Density Arc Plasma as a New Source for WiPAL

    NASA Astrophysics Data System (ADS)

    Waleffe, Roger; Endrizzi, Doug; Myers, Rachel; Wallace, John; Clark, Mike; Forest, Cary; WiPAL Team

    2016-10-01

    The Wisconsin Plasma Astrophysics Lab (WiPAL) has installed a new array of nineteen plasma sources (plasma guns) on its 3 m diameter, spherical vacuum vessel. Each gun is a cylindrical, molybdenum, washer-stabilized, arc plasma source. During discharge, the guns are maintained at 1.2 kA across 100 V for 10 ms by the gun power supply establishing a high density plasma. Each plasma source is fired independently allowing for adjustable plasma parameters, with densities varying between 1018 -1019 m-3 and electron temperatures of 5-15 eV. Measurements were characterized using a 16 tip Langmuir probe. The plasma source will be used as a background plasma for the magnetized coaxial plasma gun (MCPG), the Terrestrial Reconnection Experiment (TREX), and as the plasma source for a magnetic mirror experiment. Temperature, density, and confinement results will be presented. This work is supported by the DoE and the NSF.

  17. Racial differences of endothelial function and plasma endothelin 1 level in preclinical Tibetan and Han male population.

    PubMed

    Yang, B; Zhao, H; Zhang, J; Jiang, B; Li, C W; Cao, Y K; Cao, F

    2016-07-01

    The differences in endothelial function between Tibetan and Han nationality population have not been fully investigated. The aim of this work is to investigate the differences in endothelial function and plasma endothelin 1 (ET-1) concentration between Tibetan and Han male population. Totally 272 Tibetan male subjects aged 42.9 ± 9.4 years were enrolled in this study to stand for Tibetan population. All of them were native residents in Lhasa City. And 580 Qinghai-Tibet Railway constructors with Han nationality aged 41.8 ± 11.1 years were enrolled in this study to stand for Han nationality population. All of them were male subjects and lived in Lhasa City for at least 1 year. All subjects lived in the same high-altitude area (the altitude of Lhasa is 3658 m). Height, weight, waist circumference, hip circumference, systolic blood pressure, diastolic blood pressure were evaluated. Body mass index (BMI) was calculated. Brachial artery flow-mediated dilation (FMD) was measured in the fasting state using high-resolution B-mode ultrasound. Computer-assisted analysis software was used to calculate brachial artery diameters. Venous blood was sampled for the measurement of total cholesterol (CH), triglyceride (TG), high density lipoprotein cholesterol (HDL), low density lipoprotein cholesterol (LDL) and HbA1c. Plasma ET-1 was quantitated using a commercially available ELISA kits. Totally 272 Tibetan subjects and 580 Han nationality subjects were enrolled in this study. BMI and waist-hip ratio in Tibetan subjects were much higher than those in Han subjects (p < 0.01). LDL cholesterol level and plasma ET-1 concentration in Tibetan subjects were significantly higher than Han subjects (p < 0.01). The baseline brachial artery diameter in Tibetan group was much higher than that of Han group (p < 0.01). The absolute and percent changes in brachial artery diameter were lower in Tibetan population compared with Han population (p < 0.01). The linear regression analysis showed that LDL cholesterol, and plasma ET-1 were correlated with FMD (p < 0.01). Endothelial function and plasma ET-1 concentration were different between Tibetan and Han male populations.

  18. Collisional relaxation of an isotopic, strongly magnetized pure ion plasma and topics in resonant wave-particle interaction of plasmas

    NASA Astrophysics Data System (ADS)

    Chim, Chi Yung

    First in Chapter 2, we discuss the collisional relaxation of a strongly magnetized pure ion plasma that is composed of two species with slightly different masses, but both with singly-ionized atoms. In a limit of high cyclotron frequencies O j, the total cyclotron action Ij for the two species are adiabatic invariants. In a few collisions, maximizing entropy yields a modified Gibbs distribution of the form exp[-H/T ∥-alpha1 I 1-alpha2I2]. Here, H is the total Hamiltonian and alphaj's are related to parallel and perpendicular temperatures through T ⊥j=(1/T∥ +alphaj/Oj) -1. On a longer timescale, the two species share action so that alpha 1 and alpha2 relax to a common value alpha. On an even longer timescale, the total action ceases to be a constant of the motion and alpha relaxes to zero. Next, weak transport produces a low density halo of electrons moving radially outward from the pure electron plasma core, and the m = 1 mode begins to damp algebraically when the halo reaches the wall. The damping rate is proportional to the particle flux through the resonant layer at the wall. Chapter 3 explains analytically the new algebraic damping due to both mobility and diffusion transport. Electrons swept around the resonant "cat's eye" orbits form a dipole (m = 1) density distribution, setting up a field that produces ExB-drift of the core back to the axis, that is, damps the mode. Finally, Chapter 4 provides a simple mechanistic interpretation of the resonant wave-particle interaction of Landau. For the simple case of a Vlasov plasma oscillation, the non-resonant electrons are driven resonantly by the bare electric field from the resonant electrons, and this complex driver field is of a phase to reduce the oscillation amplitude. The wave-particle resonant interaction also occurs in 2D ExB-drift waves, such as a diocotron wave. In this case, the bare electric field from the resonant electrons causes ExB-drift motion back in the core plasma, thus damping the wave.

  19. Neutral-depletion-induced axially asymmetric density in a helicon source and imparted thrust

    NASA Astrophysics Data System (ADS)

    Takahashi, Kazunori; Takao, Yoshinori; Ando, Akira

    2016-02-01

    The high plasma density downstream of the source is observed to be sustained only for a few hundreds of microsecond at the initial phase of the discharge, when pulsing the radiofrequency power of a helicon plasma thruster. Measured relative density of argon neutrals inside the source implies that the neutrals are significantly depleted there. A position giving a maximum plasma density temporally moves to the upstream side of the source due to the neutral depletion and then the exhausted plasma density significantly decreases. The direct thrust measurement demonstrates that the higher thrust-to-power ratio is obtained by using only the initial phase of the high density plasma, compared with the steady-state operation.

  20. Differences in seminal plasma and spermatozoa antioxidative systems and seminal plasma lipid and protein levels among boar breeds and hybrid genetic traits.

    PubMed

    Žura Žaja, Ivona; Samardžija, Marko; Vince, Silvijo; Vilić, Marinko; Majić-Balić, Ivanka; Đuričić, Dražen; Milinković-Tur, Suzana

    2016-07-01

    The objectives of this study were to determine the influence of breed and hybrid genetic traits of boars on lipid and protein concentrations and antioxidative system variables in seminal plasma (SP) and spermatozoa and their correlations with semen quality variables. Semen samples from 27 boars: Swedish Landraces (SL), German Landraces (GL), Large Whites (LW), Pietrains (P) and Pig Improvement Company hybrids (PIC-hybrid), aged from 1.5 to 3 years old, were collected. SP was spectrophotometrically analyzed to determine total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triacylglycerol (TAG), total protein (TP), albumin, and zinc concentrations. The antioxidative system in SP and spermatozoa was established spectrophotometrically by determining total antioxidative status (TAS), total superoxide dismutase (TSOD) and glutathione peroxidase (GSH-Px) parameters, as well as copper-zinc superoxide dismutase (CuZnSOD) and manganese superoxide dismutase (MnSOD) activity in spermatozoa. The hybrid boars had higher (P<0.05) SP concentrations of: TC, LDL-C and TAG than P and GL; HDL-C than P, GL and SL; and TP than P and LW. PIC-hybrid had lower values (P<0.05) in spermatozoa of: TAS and CuZnSOD than SL; TSOD and GSH-Px than SL and P; and MnSOD than SL and LW. Differences in SP and spermatozoa antioxidative system variables and the significant differences in SP protein and lipid variables exist among boars of different breeds and hybrid. Novel data and observed differences in semen variables among boar breeds and hybrids and their correlations with semen quality parameters in this study could contribute to better assessment of boar semen quality. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. Experimental characterization of a coaxial plasma accelerator for a colliding plasma experiment

    NASA Astrophysics Data System (ADS)

    Wiechula, J.; Hock, C.; Iberler, M.; Manegold, T.; Schönlein, A.; Jacoby, J.

    2015-04-01

    We report experimental results of a single coaxial plasma accelerator in preparation for a colliding plasma experiment. The utilized device consisted of a coaxial pair of electrodes, accelerating the plasma due to J ×B forces. A pulse forming network, composed of three capacitors connected in parallel, with a total capacitance of 27 μF was set up. A thyratron allowed to switch the maximum applied voltage of 9 kV. Under these conditions, the pulsed currents reached peak values of about 103 kA. The measurements were performed in a small vacuum chamber with a neutral-gas prefill at gas pressures between 10 Pa and 14 000 Pa. A gas mixture of ArH2 with 2.8% H2 served as the discharge medium. H2 was chosen in order to observe the broadening of the Hβ emission line and thus estimate the electron density. The electron density for a single plasma accelerator reached peak values on the order of 1016 cm-3 . Electrical parameters, inter alia inductance and resistance, were determined for the LCR circuit during the plasma acceleration as well as in a short circuit case. Depending on the applied voltage, the inductance and resistance reached values ranging from 194 nH to 216 nH and 13 mΩ to 23 mΩ, respectively. Furthermore, the plasma velocity was measured using a fast CCD camera. Plasma velocities of 2 km/s up to 17 km/s were observed, the magnitude being highly correlated with gas pressure and applied voltage.

  2. [The influence of single moderate exercise on the sympathetic nervous system activity in patients with essential hypertension].

    PubMed

    Gajek, Jacek; Zyśko, Dorota

    2002-12-01

    Sympathetic nervous system may play an important role in development and maintenance of hypertension. Its activity can be assessed by plasma levels of catecholamines, neuropeptide Y (NPY) and adrenergic receptor density. Hypertensive subjects may be more prone to reveal overactivity of sympathetic nervous system, for instance as a result of physical stress. The aim of the study was to determine the activity of sympathetic nervous system in young patients with newly recognized, untreated mild hypertension. The study was carried out in 22 patients (age 38.5 +/- 10.3 years) and 20 normotensive volunteers (age 38.5 +/- 8.6 years) as a control group, matched for sex. Density of alpha 2- and beta-adrenergic receptors using 3H-yohimbine and 125I-cyanopindolol respectively, total catecholamines and plasma renin activity using radioenzymatic assay, neuropeptide Y and aldosterone using radioimmunoassay were assessed in the blood taken in the supine position and after moderate bicycle ergometer exercise. Plasma concentration of NPY at rest did not differ between the groups, but increased significantly after exercise and was greater in hypertensive patients (p < 0.05). The density of alpha 2- and beta-adrenergic receptors at rest and after exercise in hypertensive subjects was unchanged when comparing to healthy individuals. The plasma concentrations of endogenous catecholamines, plasma renin activity and aldosterone level increase during exercise in both studied groups (p < 0.05). Aldosterone level was higher in hypertensive patients at rest (p < 0.05). There was a negative correlation between baseline aldosterone and NPY levels in hypertensive patients (r = -0.44, p < 0.05). Moderate exercise in hypertensive subjects causes the hyperactivity of sympathetic nervous system expressed as increase of NPY plasma level.

  3. Advanced Thomson scattering system for high-flux linear plasma generator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meiden, H. J. van der; Lof, A. R.; Berg, M. A. van den

    2012-12-15

    An advanced Thomson scattering system has been built for a linear plasma generator for plasma surface interaction studies. The Thomson scattering system is based on a Nd:YAG laser operating at the second harmonic and a detection branch featuring a high etendue (f /3) transmission grating spectrometer equipped with an intensified charged coupled device camera. The system is able to measure electron density (n{sub e}) and temperature (T{sub e}) profiles close to the output of the plasma source and, at a distance of 1.25 m, just in front of a target. The detection system enables to measure 50 spatial channels ofmore » about 2 mm each, along a laser chord of 95 mm. By summing a total of 30 laser pulses (0.6 J, 10 Hz), an observational error of 3% in n{sub e} and 6% in T{sub e} (at n{sub e}= 9.4 Multiplication-Sign 10{sup 18} m{sup -3}) can be obtained. Single pulse Thomson scattering measurements can be performed with the same accuracy for n{sub e} > 2.8 Multiplication-Sign 10{sup 20} m{sup -3}. The minimum measurable density and temperature are n{sub e} < 1 Multiplication-Sign 10{sup 17} m{sup -3} and T{sub e} < 0.07 eV, respectively. In addition, using the Rayleigh peak, superimposed on the Thomson scattered spectrum, the neutral density (n{sub 0}) of the plasma can be measured with an accuracy of 25% (at n{sub 0}= 1 Multiplication-Sign 10{sup 20} m{sup -3}). In this report, the performance of the Thomson scattering system will be shown along with unprecedented accurate Thomson-Rayleigh scattering measurements on a low-temperature argon plasma expansion into a low-pressure background.« less

  4. Laser beat wave excitation of terahertz radiation in a plasma slab

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chauhan, Santosh; Parashar, Jetendra, E-mail: j.p.parashar@gmail.com

    2014-10-15

    Terahertz (THz) radiation generation by nonlinear mixing of lasers, obliquely incident on a plasma slab is investigated. Two cases are considered: (i) electron density profile is parabolic but density peak is below the critical density corresponding to the beat frequency, (ii) plasma boundaries are sharp and density is uniform. In both cases, nonlinearity arises through the ponderomotive force that gives rise to electron drift at the beat frequency. In the case of inhomogeneous plasma, non zero curl of the nonlinear current density gives rise to electromagnetic THz generation. In case of uniform plasma, the sharp density variation at the plasmamore » boundaries leads to radiation generation. In a slab width of less than a terahertz wavelength, plasma density one fourth of terahertz critical density, laser intensities ∼10{sup 17 }W/cm{sup 2} at 1 μm, one obtains the THz intensity ∼1 GW/cm{sup 2} at 3 THz radiation frequency.« less

  5. Concentrations of Plasma Free Palmitoleic and Dihomo-Gamma Linoleic Fatty Acids Are Higher in Children with Abdominal Obesity.

    PubMed

    Aristizabal, Juan C; González-Zapata, Laura I; Estrada-Restrepo, Alejandro; Monsalve-Alvarez, Julia; Restrepo-Mesa, Sandra L; Gaitán, Diego

    2018-01-01

    Increased plasma free fatty acids (FFAs) are associated with cardiometabolic risk factors in adults with abdominal obesity (AO). However, this association remains controversial in children. This study analyzed plasma FFA concentration in children with and without AO. Twenty-nine children classified with AO were matched by age and sex with 29 non-obese individuals. Blood samples were collected after fasting for 10-12 h. Plasma concentration of glucose, insulin, triglycerides, total cholesterol, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) were determined by automatized methods. FFAs were analyzed by gas chromatography. Children with and without AO had similar age (7.1 ± 2.6 vs. 7.2 ± 2.7 years; p > 0.05) but obese children showed higher ( p < 0.05) body mass index (BMI) (+4.3 kg/m²), systolic blood pressure (+5.1 mmHg), and insulin (+27.8 pmol/L). There were no significant differences in plasma total FFA concentration between groups (1.02 ± 0.61 vs. 0.89 ± 0.37 mmol/L; p > 0.05). However, children with AO had higher palmitoleic acid (0.94 vs. 0.70 wt %; p < 0.05) and dihomo-gamma linoleic acid (DHGL) (2.76 vs. 2.07 wt %; p < 0.05). Palmitoleic and DHGL acids correlated ( p < 0.05) with BMI ( r = 0.397; r = 0.296, respectively) and with waist circumference ( r = 0.380; r = 0.276, respectively). Palmitoleic acid correlated positively with systolic blood pressure ( r = 0.386; p < 0.05) and negatively with HDL-C (-0.572; p < 0.01). In summary, children with AO have higher plasmatic concentrations of free palmitoleic and DHGL fatty acids, which correlate with cardiometabolic risk factors.

  6. Concentrations of Plasma Free Palmitoleic and Dihomo-Gamma Linoleic Fatty Acids Are Higher in Children with Abdominal Obesity

    PubMed Central

    González-Zapata, Laura I.; Estrada-Restrepo, Alejandro; Monsalve-Alvarez, Julia; Restrepo-Mesa, Sandra L.; Gaitán, Diego

    2018-01-01

    Increased plasma free fatty acids (FFAs) are associated with cardiometabolic risk factors in adults with abdominal obesity (AO). However, this association remains controversial in children. This study analyzed plasma FFA concentration in children with and without AO. Twenty-nine children classified with AO were matched by age and sex with 29 non-obese individuals. Blood samples were collected after fasting for 10–12 h. Plasma concentration of glucose, insulin, triglycerides, total cholesterol, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) were determined by automatized methods. FFAs were analyzed by gas chromatography. Children with and without AO had similar age (7.1 ± 2.6 vs. 7.2 ± 2.7 years; p > 0.05) but obese children showed higher (p < 0.05) body mass index (BMI) (+4.3 kg/m2), systolic blood pressure (+5.1 mmHg), and insulin (+27.8 pmol/L). There were no significant differences in plasma total FFA concentration between groups (1.02 ± 0.61 vs. 0.89 ± 0.37 mmol/L; p > 0.05). However, children with AO had higher palmitoleic acid (0.94 vs. 0.70 wt %; p < 0.05) and dihomo-gamma linoleic acid (DHGL) (2.76 vs. 2.07 wt %; p < 0.05). Palmitoleic and DHGL acids correlated (p < 0.05) with BMI (r = 0.397; r = 0.296, respectively) and with waist circumference (r = 0.380; r = 0.276, respectively). Palmitoleic acid correlated positively with systolic blood pressure (r = 0.386; p < 0.05) and negatively with HDL-C (−0.572; p < 0.01). In summary, children with AO have higher plasmatic concentrations of free palmitoleic and DHGL fatty acids, which correlate with cardiometabolic risk factors. PMID:29301242

  7. Turbulence and transport in high density, increased β LAPD plasmas

    NASA Astrophysics Data System (ADS)

    Rossi, Giovanni; Carter, Troy; Guice, Danny

    2014-10-01

    A new LaB6 cathode plasma source has recently been deployed on the Large Plasma Device (LAPD), allowing for the production of significantly higher plasma density (ne ~ 3 ×1013 cm-3) and temperature (Te ~ 12 eV and Ti ~ 6 eV). This source produces a smaller core plasma (~20cm diameter) that can be embedded in the lower temperature, lower density standard LAPD plasma (60 cm diameter, 1012 cm-3, Te ~ 5 eV, Ti ~ 1 eV). We will present first results from experiments exploring the nature of turbulence and transport produced by this high density core plasma. In contrast to the edge of the standard LAPD plasma, coherent fluctuations are observed in the edge of the high density core plasma. These coherent modes are dominant at low field (~400 G) with a transition to a more broadband spectrum at higher fields (~1 kG). The combination of increased density and temperature with lowered field in LAPD leads to significant increases in plasma β (in fact β ~ 1 can be achieved for B ~ 100 G). As the field is lowered, the strength of correlated magnetic fluctuations increases substantially.

  8. Hydrodynamic Model for Density Gradients Instability in Hall Plasmas Thrusters

    NASA Astrophysics Data System (ADS)

    Singh, Sukhmander

    2017-10-01

    There is an increasing interest for a correct understanding of purely growing electromagnetic and electrostatic instabilities driven by a plasma gradient in a Hall thruster devices. In Hall thrusters, which are typically operated with xenon, the thrust is provided by the acceleration of ions in the plasma generated in a discharge chamber. The goal of this paper is to study the instabilities due to gradients of plasma density and conditions for the growth rate and real part of the frequency for Hall thruster plasmas. Inhomogeneous plasmas prone a wide class of eigen modes induced by inhomogeneities of plasma density and called drift waves and instabilities. The growth rate of the instability has a dependences on the magnetic field, plasma density, ion temperature and wave numbers and initial drift velocities of the plasma species.

  9. Novel Approach to Evaluation of Charging on Semiconductor Surface by Noncontact, Electrode-Free Capacitance/Voltage Measurement

    NASA Astrophysics Data System (ADS)

    Hirae, Sadao; Kohno, Motohiro; Okada, Hiroshi; Matsubara, Hideaki; Nakatani, Ikuyoshi; Kusuda, Tatsufumi; Sakai, Takamasa

    1994-04-01

    This paper describes a novel approach to the quantitative characterization of semiconductor surface charging caused by plasma exposures and ion implantations. The problems in conventional evaluation of charging are also discussed. Following the discussions above, the necessity of unified criteria is suggested for efficient development of systems or processes without charging damage. Hence, the charging saturation voltage between a top oxide surface and substrate, V s, and the charging density per unit area per second, ρ0, should be taken as criteria of charging behavior, which effectively represent the charging characteristics of both processes. The unified criteria can be obtained from the exposure time dependence of a net charging density on the thick field oxide. In order to determine V s and ρ0, the analysis using the C-V curve measured in a noncontact method with the metal-air-insulator-semiconductor (MAIS) technique is employed. The total space-charge density in oxide and its centroid can be determined at the same time by analyzing the flat-band voltage (V fb) of the MAIS capacitor as a function of the air gap. The net charge density can be obtained by analyzing the difference between the total space-charge density in oxide before and after charging. Finally, it is shown that charge damage of the large area metal-oxide-semiconductor (MOS) capacitor can be estimated from both V s and ρ0 which are obtained from results for a thick field oxide implanted with As+ and exposed to oxygen plasma.

  10. First results from the Thomson scattering diagnostic on proto-MPEX

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Biewer, T. M., E-mail: biewertm@ornl.gov; Meitner, S.; Rapp, J.

    2016-11-15

    A Thomson scattering (TS) diagnostic has been successfully implemented on the prototype Material Plasma Exposure eXperiment (Proto-MPEX) at Oak Ridge National Laboratory. The diagnostic collects the light scattered by plasma electrons and spectroscopically resolves the Doppler shift imparted to the light by the velocity of the electrons. The spread in velocities is proportional to the electron temperature, while the total number of photons is proportional to the electron density. TS is a technique used on many devices to measure the electron temperature (T{sub e}) and electron density (n{sub e}) of the plasma. A challenging aspect of the technique is tomore » discriminate the small number of Thomson scattered photons against the large peak of background photons from the high-power laser used to probe the plasma. A variety of methods are used to mitigate the background photons in Proto-MPEX, including Brewster angled windows, viewing dumps, and light baffles. With these methods, first results were measured from argon plasmas in Proto-MPEX, indicating T{sub e} ∼ 2 eV and n{sub e} ∼ 1 × 10{sup 19} m{sup −3}. The configuration of the Proto-MPEX TS diagnostic will be described and plans for improvement will be given.« less

  11. Development of optics for x-ray phase-contrast imaging of high energy density plasmas.

    PubMed

    Stutman, D; Finkenthal, M; Moldovan, N

    2010-10-01

    Phase-contrast or refraction-enhanced x-ray radiography can be useful for the diagnostic of low-Z high energy density plasmas, such as imploding inertial confinement fusion (ICF) pellets, due to its sensitivity to density gradients. To separate and quantify the absorption and refraction contributions to x-ray images, methods based on microperiodic optics, such as shearing interferometry, can be used. To enable applying such methods with the energetic x rays needed for ICF radiography, we investigate a new type of optics consisting of grazing incidence microperiodic mirrors. Using such mirrors, efficient phase-contrast imaging systems could be built for energies up to ∼100 keV. In addition, a simple lithographic method is proposed for the production of the microperiodic x-ray mirrors based on the difference in the total reflection between a low-Z substrate and a high-Z film. Prototype mirrors fabricated with this method show promising characteristics in laboratory tests.

  12. Barium-strontium-titanate etching characteristics in chlorinated discharges

    NASA Astrophysics Data System (ADS)

    Stafford, Luc; Margot, Joëlle; Langlois, Olivier; Chaker, Mohamed

    2003-07-01

    The etching characteristics of barium-strontium-titanate (BST) were investigated using a high-density plasma sustained by surface waves at 190 MHz in Ar/Cl2 gas mixtures. The etch rate was examined as a function of both the total gas pressure and the Cl2 fraction in Ar/Cl2 using a wafer temperature of 10 °C. The results were correlated to positive ion density and plasma composition obtained from Langmuir probes and mass spectrometry. The BST etch rate was found to increase linearly with the positive ion density and to decrease with increasing chlorine atom concentration. This result indicates that for the temperature conditions used, the interaction between chlorine and BST yields compounds having a volatility that is lower than the original material. As a consequence, the contribution of neutral atomic Cl atoms to the etch mechanism is detrimental, thereby reducing the etch rate. As the wafer temperature increases, the role of chemistry in the etching process is enhanced.

  13. Confinement time exceeding one second for a toroidal electron plasma.

    PubMed

    Marler, J P; Stoneking, M R

    2008-04-18

    Nearly steady-state electron plasmas are trapped in a toroidal magnetic field for the first time. We report the first results from a new toroidal electron plasma experiment, the Lawrence Non-neutral Torus II, in which electron densities on the order of 10(7) cm(-3) are trapped in a 270-degree toroidal arc (670 G toroidal magnetic field) by application of trapping potentials to segments of a conducting shell. The total charge inferred from measurements of the frequency of the m=1 diocotron mode is observed to decay on a 3 s time scale, a time scale that approaches the predicted limit due to magnetic pumping transport. Three seconds represents approximately equal to 10(5) periods of the lowest frequency plasma mode, indicating that nearly steady-state conditions are achieved.

  14. Initial results in SST-1 after up-gradation

    NASA Astrophysics Data System (ADS)

    Pradhan, S.; Khan, Z.; Tanna, V. L.; Prasad, U.; Paravastu, Y.; Raval, D. C.; Masand, H.; Kumar, Aveg; Dhongde, J. R.; Jana, S.; Kakati, B.; Patel, K. B.; Bhandarkar, M. K.; Shukla, B. K.; Ghosh, D.; Patel, H. S.; Parekh, T. J.; Mansuri, I. A.; Dhanani, K. R.; Varadharajulu, A.; Khristi, Y. S.; Biswas, P.; Gupta, C. N.; George, S.; Semwal, P.; Sharma, D. K.; Gulati, H. K.; Mahajan, K.; Praghi, B. R.; Banaudha, M.; Makwana, A. R.; Chudasma, H. H.; Kumar, M.; Manchanda, R.; Joisa, Y. S.; Asudani, K.; Pandya, S. N.; Pathak, S. K.; Banerjee, S.; Patel, P. J.; Santra, P.; Pathan, F. S.; Chauhan, P. K.; Khan, M. S.; Thankey, P. L.; Prakash, A.; Panchal, P. N.; Panchal, R. N.; Patel, R. J.; Mahsuria, G. I.; Sonara, D. P.; Patel, K. M.; Jayaswal, S. P.; Sharma, M.; Patel, J. C.; Varmora, P.; Srikanth, G. L. N.; Christian, D. R.; Garg, A.; Bairagi, N.; Babu, G. R.; Panchal, A. G.; Vora, M. M.; Singh, A. K.; Sharma, R.; Nimavat, H. D.; Shah, P. R.; Purwar, G.; Raval, T. Y.; Sharma, A. L.; Ojha, A.; Kumar, S.; Ramaiya, N. K.; Siju, V.; Gopalakrishna, M. V.; Kumar, A.; Sharma, P. K.; Atrey, P. K.; Kulkarni, SV; Ambulkar, K. K.; Parmar, P. R.; Thakur, A. L.; Raval, J. V.; Purohit, S.; Mishra, P. K.; Adhiya, A. N.; Nagora, U. C.; Thomas, J.; Chaudhari, V. K.; Patel, K. G.; Dalakoti, S.; Virani, C. G.; Gupta, S.; Kumar, Ajay; Chaudhari, B.; Kaur, R.; Srinivasan, R.; Raju, D.; Kanabar, D. H.; Jha, R.; Das, A.; Bora, D.

    2017-04-01

    SST-1 Tokamak has recently completed the 1st phase of up-gradation with successful installation and integration of all its First Wall components. The First Wall of SST-1 comprises of ∼ 3800 high heat flux compatible graphite tiles being assembled and installed on 132 CuCrZr heat sink back plates engraved with ∼ 4 km of leak tight baking and cooling channels in five major sub groups equipped with ∼ 400 sensors and weighing ∼ 6000 kg in total in thirteen isolated galvanic and six isolated hydraulic circuits. The phase-1 up-gradation spectrum also includes addition of Supersonic Molecular Beam Injection (SMBI) both on the in-board and out-board side, installation of fast reciprocating probes, adding some edge plasma probe diagnostics in the SOL region, installation and integration of segmented and up-down symmetric radial coils aiding/controlling plasma rotations, introduction of plasma position feedback and density controls etc. Post phase-I up-gradation spanning from Nov 2014 till June 2016, initial plasma experiments in up-graded SST-1 have begun since Aug 2016 after a brief engineering validation period in SST-1. The first experiments in SST-1 have revealed interesting aspects on the ‘eddy currents in the First Wall support structures’ influencing the ‘magnetic Null evolution dynamics’ and the subsequent plasma start-up characteristics after the ECH pre-ionization, the influence of the first walls on the ‘field errors’ and the resulting locked modes observed, the magnetic index influencing the evolution of the equilibrium of the plasma column, low density supra-thermal electron induced discharges and normal ohmic discharges etc. Presently; repeatable ohmic discharges regimes in SST-1 having plasma currents in excess of 65 KA (qa ∼ 3.8, BT = 1.5 T) with a current ramp rates ∼ 1.2 MA/s over a duration of ∼ 300 ms with line averaged densities ∼ 0.8 × 1019 and temperatures ∼ 200 eV with copious MHD signatures have been experimentally established. Further elongation of the plasma duration up to one second or more with position and density feedback as well as coupling of Lower Hybrid waves are currently being persuaded in SST-1 apart from increasing the core plasma parameters with further optimizations and with wall conditioning.

  15. Electron density and plasma dynamics of a colliding plasma experiment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wiechula, J., E-mail: wiechula@physik.uni-frankfurt.de; Schönlein, A.; Iberler, M.

    2016-07-15

    We present experimental results of two head-on colliding plasma sheaths accelerated by pulsed-power-driven coaxial plasma accelerators. The measurements have been performed in a small vacuum chamber with a neutral-gas prefill of ArH{sub 2} at gas pressures between 17 Pa and 400 Pa and load voltages between 4 kV and 9 kV. As the plasma sheaths collide, the electron density is significantly increased. The electron density reaches maximum values of ≈8 ⋅ 10{sup 15} cm{sup −3} for a single accelerated plasma and a maximum value of ≈2.6 ⋅ 10{sup 16} cm{sup −3} for the plasma collision. Overall a raise of the plasma density by a factor ofmore » 1.3 to 3.8 has been achieved. A scaling behavior has been derived from the values of the electron density which shows a disproportionately high increase of the electron density of the collisional case for higher applied voltages in comparison to a single accelerated plasma. Sequences of the plasma collision have been taken, using a fast framing camera to study the plasma dynamics. These sequences indicate a maximum collision velocity of 34 km/s.« less

  16. Calibrating ion density profile measurements in ion thruster beam plasma

    NASA Astrophysics Data System (ADS)

    Zhang, Zun; Tang, Haibin; Ren, Junxue; Zhang, Zhe; Wang, Joseph

    2016-11-01

    The ion thruster beam plasma is characterized by high directed ion velocity (104 m/s) and low plasma density (1015 m-3). Interpretation of measurements of such a plasma based on classical Langmuir probe theory can yield a large experimental error. This paper presents an indirect method to calibrate ion density determination in an ion thruster beam plasma using a Faraday probe, a retarding potential analyzer, and a Langmuir probe. This new method is applied to determine the plasma emitted from a 20-cm-diameter Kaufman ion thruster. The results show that the ion density calibrated by the new method can be as much as 40% less than that without any ion current density and ion velocity calibration.

  17. Towards Attosecond High-Energy Electron Bunches: Controlling Self-Injection in Laser-Wakefield Accelerators Through Plasma-Density Modulation

    NASA Astrophysics Data System (ADS)

    Tooley, M. P.; Ersfeld, B.; Yoffe, S. R.; Noble, A.; Brunetti, E.; Sheng, Z. M.; Islam, M. R.; Jaroszynski, D. A.

    2017-07-01

    Self-injection in a laser-plasma wakefield accelerator is usually achieved by increasing the laser intensity until the threshold for injection is exceeded. Alternatively, the velocity of the bubble accelerating structure can be controlled using plasma density ramps, reducing the electron velocity required for injection. We present a model describing self-injection in the short-bunch regime for arbitrary changes in the plasma density. We derive the threshold condition for injection due to a plasma density gradient, which is confirmed using particle-in-cell simulations that demonstrate injection of subfemtosecond bunches. It is shown that the bunch charge, bunch length, and separation of bunches in a bunch train can be controlled by tailoring the plasma density profile.

  18. Plasma distributions in meteor head echoes and implications for radar cross section interpretation

    NASA Astrophysics Data System (ADS)

    Marshall, Robert A.; Brown, Peter; Close, Sigrid

    2017-09-01

    The derivation of meteoroid masses from radar measurements requires conversion of the measured radar cross section (RCS) to meteoroid mass. Typically, this conversion passes first through an estimate of the meteor plasma density derived from the RCS. However, the conversion from RCS to meteor plasma density requires assumptions on the radial electron density distribution. We use simultaneous triple-frequency measurements of the RCS for 63 large meteor head echoes to derive estimates of the meteor plasma size and density using five different possible radial electron density distributions. By fitting these distributions to the observed meteor RCS values and estimating the goodness-of-fit, we determine that the best fit to the data is a 1 /r2 plasma distribution, i.e. the electron density decays as 1 /r2 from the center of the meteor plasma. Next, we use the derived plasma distributions to estimate the electron line density q for each meteor using each of the five distributions. We show that depending on the choice of distribution, the line density can vary by a factor of three or more. We thus argue that a best estimate for the radial plasma distribution in a meteor head echo is necessary in order to have any confidence in derived meteoroid masses.

  19. Investigation of mechanism of anode plasma formation in ion diode with dielectric anode

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pushkarev, A., E-mail: aipush@mail.ru

    The results of investigation of the anode plasma formation in a diode with a passive anode in magnetic insulation mode are presented. The experiments have been conducted using the BIPPAB-450 ion accelerator (350–400 kV, 6–8 kA, 80 ns) with a focusing conical diode with B{sub r} external magnetic field (a barrel diode). For analysis of plasma formation at the anode and the distribution of the ions beam energy density, infrared imaging diagnostics (spatial resolution of 1–2 mm) is used. For analysis of the ion beam composition, time-of-flight diagnostics (temporal resolution of 1 ns) were used. Our studies have shown that when the magnetic induction inmore » the A-C gap is much larger than the critical value, the ion beam energy density is close to the one-dimensional Child-Langmuir limit on the entire working surface of the diode. Formation of anode plasma takes place only by the flashover of the dielectric anode surface. In this mode, the ion beam consists primarily of singly ionized carbon ions, and the delay of the start of formation of the anode plasma is 10–15 ns. By reducing the magnetic induction in the A-C gap to a value close to the critical one, the ion beam energy density is 3–6 times higher than that calculated by the one-dimensional Child-Langmuir limit, but the energy density of the ion beam is non-uniform in cross-section. In this mode, the anode plasma formation occurs due to ionization of the anode material with accelerated electrons. In this mode, also, the delay in the start of the formation of the anode plasma is much smaller and the degree of ionization of carbon ions is higher. In all modes occurred effective suppression of the electronic component of the total current, and the diode impedance was 20–30 times higher than the values calculated for the mode without magnetic insulation of the electrons. The divergence of the ion beam was 4.5°–6°.« less

  20. Dynamics of the formation and loss of boron atoms in a H2/B2H6 microwave plasma

    NASA Astrophysics Data System (ADS)

    Duluard, C. Y.; Aubert, X.; Sadeghi, N.; Gicquel, A.

    2016-09-01

    For further improvements in doped-diamond deposition technology, an understanding of the complex chemistry in H2/CH4/B2H6 plasmas is of general importance. In this context, a H2/B2H6 plasma ignited by microwave power in a near resonant cavity at high pressure (100-200 mbar) is studied to measure the B-atom density in the ground state. The discharge is ignited in the gas mixture (0-135 ppm B2H6 in H2) by a 2.45 GHz microwave generator, leading to the formation of a hemispheric plasma core, surrounded by a faint discharge halo filling the remaining reactor volume. Measurements with both laser induced fluorescence and resonant absoption with a boron hollow cathode lamp indicate that the B-atom density is higher in the halo than in the plasma core. When the absorption line-of-sight is positioned in the halo, the absorption is so strong that the upper detection limit is reached. To understand the mechanisms of creation and loss of boron atoms, time-resolved absorption measurements have been carried out in a pulsed plasma regime (10 Hz, duty cycle 50%). The study focuses on the influence of the total pressure, the partial pressure of B2H6, as well as the source power, on the growth and decay rates of boron atoms when the plasma is turned off.

  1. Non-stationary self-focusing of intense laser beam in plasma using ramp density profile

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Habibi, M.; Ghamari, F.

    2011-10-15

    The non-stationary self-focusing of high intense laser beam in under-dense plasma with upward increasing density ramp is investigated. The obtained results show that slowly increasing plasma density ramp is very important in enhancing laser self-focusing. Also, the spot size oscillations of laser beam in front and rear of the pulse for two different density profiles are shown. We have selected density profiles that already were used by Sadighi-Bonabi et al.[Phys. Plasmas 16, 083105 (2009)]. Ramp density profile causes the laser beam to become more focused and penetrations deeps into the plasma by reduction of diffraction effects. Our computations show moremore » reliable results in comparison to the previous works.« less

  2. Time resolved interferometric study of the plasma plume induced shock wave in confined geometry: Two-dimensional mapping of the ambient and plasma density

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Choudhury, Kaushik; Singh, R. K.; Kumar, Ajai, E-mail: ajai@ipr.res.in

    2016-04-15

    An experimental investigation of the laser produced plasma induced shock wave in the presence of confining walls placed along the axial as well as the lateral direction has been performed. A time resolved Mach Zehnder interferometer is set up to track the primary as well as the reflected shock waves and its effect on the evolving plasma plume has been studied. An attempt has been made to discriminate the electronic and medium density contributions towards the changes in the refractive index of the medium. Two dimensional spatial distributions for both ambient medium density and plasma density (electron density) have beenmore » obtained by employing customised inversion technique and algorithm on the recorded interferograms. The observed density pattern of the surrounding medium in the presence of confining walls is correlated with the reflected shock wave propagation in the medium. Further, the shock wave plasma interaction and the subsequent changes in the shape and density of the plasma plume in confined geometry are briefly described.« less

  3. Current drive at plasma densities required for thermonuclear reactors.

    PubMed

    Cesario, R; Amicucci, L; Cardinali, A; Castaldo, C; Marinucci, M; Panaccione, L; Santini, F; Tudisco, O; Apicella, M L; Calabrò, G; Cianfarani, C; Frigione, D; Galli, A; Mazzitelli, G; Mazzotta, C; Pericoli, V; Schettini, G; Tuccillo, A A

    2010-08-10

    Progress in thermonuclear fusion energy research based on deuterium plasmas magnetically confined in toroidal tokamak devices requires the development of efficient current drive methods. Previous experiments have shown that plasma current can be driven effectively by externally launched radio frequency power coupled to lower hybrid plasma waves. However, at the high plasma densities required for fusion power plants, the coupled radio frequency power does not penetrate into the plasma core, possibly because of strong wave interactions with the plasma edge. Here we show experiments performed on FTU (Frascati Tokamak Upgrade) based on theoretical predictions that nonlinear interactions diminish when the peripheral plasma electron temperature is high, allowing significant wave penetration at high density. The results show that the coupled radio frequency power can penetrate into high-density plasmas due to weaker plasma edge effects, thus extending the effective range of lower hybrid current drive towards the domain relevant for fusion reactors.

  4. Statistical results from 10 years of Cassini Langmuir probe plasma measurements

    NASA Astrophysics Data System (ADS)

    Holmberg, M.; Shebanits, O.; Wahlund, J. E.; Morooka, M.; Andre, N.

    2016-12-01

    We use a new analysis method to obtain 10 years of Cassini RPWS Langmuir probe (LP) measurements to study the structure and dynamics of the inner plasma disk of Saturn. The LP plasma density measurements show good agreement with electron densities derived from the RPWS electric field power spectra and confirms and/or improves a number of previous findings about the structure of the plasma disk. E.g., the Enceladus plume is detected as a localised density maximum at the orbit of Enceladus, but the peak density of the inner plasma disk, excluding Enceladus plume passages, is located closer to 4.7 Rs. No density peaks are recorded at the orbits of the moons Mimas, Tethys, Dione, and Rhea. We confirm the previously detected plasma density dayside/nightside asymmetry, which is likely due to a particle drift in the dusk to dawn direction. Presented is also the LP result on the seasonal dependence of the plasma disk within Enceladus' orbit.

  5. Observation of 1-D time dependent non-propagating laser plasma structures using fluid and PIC codes

    NASA Astrophysics Data System (ADS)

    Verma, Deepa; Bera, Ratan Kumar; Kumar, Atul; Patel, Bhavesh; Das, Amita

    2017-12-01

    The manuscript reports the observation of time dependent localized and non-propagating structures in the coupled laser plasma system through 1-D fluid and Particle-In-Cell (PIC) simulations. It is reported that such structures form spontaneously as a result of collision amongst certain exact solitonic solutions. They are seen to survive as coherent entities for a long time up to several hundreds of plasma periods. Furthermore, it is shown that such time dependence can also be artificially recreated by significantly disturbing the delicate balance between the radiation and the density fields required for the exact non-propagating solution obtained by Esirkepov et al., JETP 68(1), 36-41 (1998). The ensuing time evolution is an interesting interplay between kinetic and field energies of the system. The electrostatic plasma oscillations are coupled with oscillations in the electromagnetic field. The inhomogeneity of the background and the relativistic nature, however, invariably produces large amplitude density perturbations leading to its wave breaking. In the fluid simulations, the signature of wave breaking can be discerned by a drop in the total energy which evidently gets lost to the grid. The PIC simulations are observed to closely follow the fluid simulations till the point of wave breaking. However, the total energy in the case of PIC simulations is seen to remain conserved throughout the simulations. At the wave breaking, the particles are observed to acquire thermal kinetic energy in the case of PIC. Interestingly, even after wave breaking, compact coherent structures with trapped radiation inside high-density peaks continue to exist both in PIC and fluid simulations. Although the time evolution does not exactly match in the two simulations as it does prior to the process of wave breaking, the time-dependent features exhibited by the remnant structures are characteristically similar.

  6. Endogenous Cholesterol Excretion Is Negatively Associated With Carotid Intima-Media Thickness in Humans.

    PubMed

    Lin, Xiaobo; Racette, Susan B; Ma, Lina; Wallendorf, Michael; Dávila-Román, Victor G; Ostlund, Richard E

    2017-12-01

    Epidemiological studies strongly suggest that lipid factors independent of low-density lipoprotein cholesterol contribute significantly to cardiovascular disease risk. Because circulating lipoproteins comprise only a small fraction of total body cholesterol, the mobilization and excretion of cholesterol from plasma and tissue pools may be an important determinant of cardiovascular disease risk. Our hypothesis is that fecal excretion of endogenous cholesterol is protective against atherosclerosis. Cholesterol metabolism and carotid intima-media thickness were quantitated in 86 nondiabetic adults. Plasma cholesterol was labeled by intravenous infusion of cholesterol-d 7 solubilized in a lipid emulsion and dietary cholesterol by cholesterol-d 5 and the nonabsorbable stool marker sitostanol-d 4 . Plasma and stool samples were collected while subjects consumed a cholesterol- and phytosterol-controlled metabolic kitchen diet and were analyzed by mass spectrometry. Carotid intima-media thickness was negatively correlated with fecal excretion of endogenous cholesterol ( r =-0.426; P <0.0001), total cholesterol ( r =-0.472; P ≤0.0001), and daily percent excretion of cholesterol from the rapidly mixing cholesterol pool ( r =-0.343; P =0.0012) and was positively correlated with percent cholesterol absorption ( r =+0.279; P =0.0092). In a linear regression model controlling for age, sex, systolic blood pressure, hemoglobin A1c, low-density lipoprotein, high-density lipoprotein cholesterol, and statin drug use, fecal excretion of endogenous cholesterol remained significant ( P =0.0008). Excretion of endogenous cholesterol is strongly, independently, and negatively associated with carotid intima-media thickness. The reverse cholesterol transport pathway comprising the intestine and the rapidly mixing plasma, and tissue cholesterol pool could be an unrecognized determinant of cardiovascular disease risk not reflected in circulating lipoproteins. Further work is needed to relate measures of reverse cholesterol transport to atherosclerotic disease. URL: http://www.clinicaltrials.gov. Unique identifier: NCT01603758. © 2017 American Heart Association, Inc.

  7. A Plasma Diagnostic Set for the Study of a Variable Specific Impulse Magnetoplasma Rocket

    NASA Astrophysics Data System (ADS)

    Squire, J. P.; Chang-Diaz, F. R.; Bengtson Bussell, R., Jr.; Jacobson, V. T.; Wootton, A. J.; Bering, E. A.; Jack, T.; Rabeau, A.

    1997-11-01

    The Advanced Space Propulsion Laboratory (ASPL) is developing a Variable Specific Impulse Magnetoplasma Rocket (VASIMR) using an RF heated magnetic mirror operated asymmetrically. We will describe the initial set of plasma diagnostics and data acquisition system being developed and installed on the VASIMR experiment. A U.T. Austin team is installing two fast reciprocating probes: a quadruple Langmuir and a Mach probe. These measure electron density and temperature profiles, electrostatic plasma fluctuations, and plasma flow profiles. The University of Houston is developing an array of 20 highly directional Retarding Potential Analyzers (RPA) for measuring ion energy distribution function profiles in the rocket plume, giving a measurement of total thrust. We have also developed a CAMAC based data acquisition system using LabView running on a Power Macintosh communicating through a 2 MB/s serial highway. We will present data from initial plasma operations and discuss future diagnostic development.

  8. Transition from wakefield generation to soliton formation.

    PubMed

    Holkundkar, Amol R; Brodin, Gert

    2018-04-01

    It is well known that when a short laser pulse propagates in an underdense plasma, it induces longitudinal plasma oscillations at the plasma frequency after the pulse, typically referred to as the wakefield. However, for plasma densities approaching the critical density, wakefield generation is suppressed, and instead the EM-pulse (electromagnetic pulse) undergoes nonlinear self-modulation. In this article we have studied the transition from the wakefield generation to formation of quasi-solitons as the plasma density is increased. For this purpose we have applied a one-dimensional relativistic cold fluid model, which has also been compared with particle-in-cell simulations. A key result is that the energy loss of the EM-pulse due to wakefield generation has its maximum for a plasma density of the order 10% of the critical density, but that wakefield generation is sharply suppressed when the density is increased further.

  9. Impact of the Hall effect on high-energy-density plasma jets.

    PubMed

    Gourdain, P-A; Seyler, C E

    2013-01-04

    Using a 1-MA, 100 ns-rise-time pulsed power generator, radial foil configurations can produce strongly collimated plasma jets. The resulting jets have electron densities on the order of 10(20) cm(-3), temperatures above 50 eV and plasma velocities on the order of 100 km/s, giving Reynolds numbers of the order of 10(3), magnetic Reynolds and Péclet numbers on the order of 1. While Hall physics does not dominate jet dynamics due to the large particle density and flow inside, it strongly impacts flows in the jet periphery where plasma density is low. As a result, Hall physics affects indirectly the geometrical shape of the jet and its density profile. The comparison between experiments and numerical simulations demonstrates that the Hall term enhances the jet density when the plasma current flows away from the jet compared to the case where the plasma current flows towards it.

  10. A high power, high density helicon discharge for the plasma wakefield accelerator experiment AWAKE

    NASA Astrophysics Data System (ADS)

    Buttenschön, B.; Fahrenkamp, N.; Grulke, O.

    2018-07-01

    A plasma cell prototype for the plasma wakefield accelerator experiment AWAKE based on a helicon discharge is presented. In the 1 m long prototype module a multiple antenna helicon discharge with an rf power density of 100 MW m‑3 is established. Based on the helicon dispersion relation, a linear scaling of plasma density with magnetic field is observed for rf frequencies above the lower hybrid frequency, ω LH ≤ 0.8ω rf. Density profiles are highest on the device axis and show shallow radial gradients, thus providing a relatively constant plasma density in the center over a radial range of Δr ≈ 10 mm with less than 10% variation. Peak plasma densities up to 7 × 1020 m‑3 are transiently achieved with a reproducibility that is sufficient for AWAKE. The results are in good agreement with power balance calculations.

  11. Transition from wakefield generation to soliton formation

    NASA Astrophysics Data System (ADS)

    Holkundkar, Amol R.; Brodin, Gert

    2018-04-01

    It is well known that when a short laser pulse propagates in an underdense plasma, it induces longitudinal plasma oscillations at the plasma frequency after the pulse, typically referred to as the wakefield. However, for plasma densities approaching the critical density, wakefield generation is suppressed, and instead the EM-pulse (electromagnetic pulse) undergoes nonlinear self-modulation. In this article we have studied the transition from the wakefield generation to formation of quasi-solitons as the plasma density is increased. For this purpose we have applied a one-dimensional relativistic cold fluid model, which has also been compared with particle-in-cell simulations. A key result is that the energy loss of the EM-pulse due to wakefield generation has its maximum for a plasma density of the order 10% of the critical density, but that wakefield generation is sharply suppressed when the density is increased further.

  12. Characterization of the C-2W Plasma Guns

    NASA Astrophysics Data System (ADS)

    Dubois, Ami; Sokolov, Vladimir; Korepanov, Sergey; Osin, Dima; Player, Gabriel; TAE Team

    2017-10-01

    Previous use of coaxial arc discharge plasma guns on the C-2U device exhibited great success in plasma stabilization and improved confinement. On the C-2W experiment, arc discharge plasma guns will again be used to facilitate the electrical connection between the plasma core and the divertor electrodes in order to maintain the electrode edge biasing and induce E x B shear to control plasma rotation. Each plasma gun contains an internal solenoid used to shape the plasma stream. Characterization of electron density (ne) , electron temperature (Te) , floating potential (Vf) , and total plasma flux in an arc discharge lasting 6 ms without the internal solenoid are presented. A Langmuir probe located 27 cm axially outside of the plasma gun anode measures a bell-like radial ne profile with peak ne 1018 m-3 and Te 2 - 10 eV. Observed spectral lines of impurity ions provide an estimate of Te, and Balmer series line ratios of the main ion component are used to evaluate ne at both the probe location and near the plasma gun anode. A calorimeter measures the plasma flux to be constant and equivalent to 1 kA.

  13. Entropy generation across Earth's collisionless bow shock.

    PubMed

    Parks, G K; Lee, E; McCarthy, M; Goldstein, M; Fu, S Y; Cao, J B; Canu, P; Lin, N; Wilber, M; Dandouras, I; Réme, H; Fazakerley, A

    2012-02-10

    Earth's bow shock is a collisionless shock wave but entropy has never been directly measured across it. The plasma experiments on Cluster and Double Star measure 3D plasma distributions upstream and downstream of the bow shock allowing calculation of Boltzmann's entropy function H and his famous H theorem, dH/dt≤0. The collisionless Boltzmann (Vlasov) equation predicts that the total entropy does not change if the distribution function across the shock becomes nonthermal, but it allows changes in the entropy density. Here, we present the first direct measurements of entropy density changes across Earth's bow shock and show that the results generally support the model of the Vlasov analysis. These observations are a starting point for a more sophisticated analysis that includes 3D computer modeling of collisionless shocks with input from observed particles, waves, and turbulences.

  14. Compensation of the sheath effects in cylindrical floating probes

    NASA Astrophysics Data System (ADS)

    Park, Ji-Hwan; Chung, Chin-Wook

    2018-05-01

    In cylindrical floating probe measurements, the plasma density and electron temperature are overestimated due to sheath expansion and oscillation. To reduce these sheath effects, a compensation method based on well-developed floating sheath theories is proposed and applied to the floating harmonic method. The iterative calculation of the Allen-Boyd-Reynolds equation can derive the floating sheath thickness, which can be used to calculate the effective ion collection area; in this way, an accurate ion density is obtained. The Child-Langmuir law is used to calculate the ion harmonic currents caused by sheath oscillation of the alternating-voltage-biased probe tip. Accurate plasma parameters can be obtained by subtracting these ion harmonic currents from the total measured harmonic currents. Herein, the measurement principles and compensation method are discussed in detail and an experimental demonstration is presented.

  15. Dietary conjugated linoleic acid alters oxidative stability and alleviates plasma cholesterol content in meat of broiler chickens.

    PubMed

    Kumari Ramiah, Suriya; Meng, Goh Yong; Ebrahimi, Mahdi

    2014-01-01

    This study was conducted to investigate the effects of dietary conjugated linoleic acid (CLA) on fatty acid composition, lipoprotein content, lipid peroxidation, and meat colour of broiler chickens. A total of 180 broiler chickens were allocated to 3 dietary treatments (0, 2.5, and 5% Lutrell) and given a standard broiler starter diet and finisher diet. Body weight of chickens and feed intake were recorded weekly. After slaughter, the breast meat was aged at 4 °C for 0, 3, and 6 days. The fatty acid composition was measured in the breast meat. Body weight (BW) and feed efficiency were decreased by dietary CLA level (P < 0.05). Chicken fed with 2.5% Lutrell had the highest feed intake compared to the control (CON) group. The total CLA increased significantly (P < 0.05) in breast meat from birds supplemented with CLA. Propensity for lipid peroxidation was significantly higher after 6 days of meat storage (P < 0.05) and the redness in chicken breast meat was lower in CLA-fed birds (P < 0.05). It is also notable that a 5% Lutrell supplementation decreased the plasma total cholesterol (TC), low density protein (LDL), and HDL (high-density lipoprotein)/LDL ratio in chickens (P < 0.05).

  16. Dietary Conjugated Linoleic Acid Alters Oxidative Stability and Alleviates Plasma Cholesterol Content in Meat of Broiler Chickens

    PubMed Central

    Kumari Ramiah, Suriya; Meng, Goh Yong

    2014-01-01

    This study was conducted to investigate the effects of dietary conjugated linoleic acid (CLA) on fatty acid composition, lipoprotein content, lipid peroxidation, and meat colour of broiler chickens. A total of 180 broiler chickens were allocated to 3 dietary treatments (0, 2.5, and 5% Lutrell) and given a standard broiler starter diet and finisher diet. Body weight of chickens and feed intake were recorded weekly. After slaughter, the breast meat was aged at 4°C for 0, 3, and 6 days. The fatty acid composition was measured in the breast meat. Body weight (BW) and feed efficiency were decreased by dietary CLA level (P < 0.05). Chicken fed with 2.5% Lutrell had the highest feed intake compared to the control (CON) group. The total CLA increased significantly (P < 0.05) in breast meat from birds supplemented with CLA. Propensity for lipid peroxidation was significantly higher after 6 days of meat storage (P < 0.05) and the redness in chicken breast meat was lower in CLA-fed birds (P < 0.05). It is also notable that a 5% Lutrell supplementation decreased the plasma total cholesterol (TC), low density protein (LDL), and HDL (high-density lipoprotein)/LDL ratio in chickens (P < 0.05). PMID:25386625

  17. Turbulence and sheared flow structures behind the isotopic dependence of the L-H power threshold on DIII-D

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yan, Zheng; Gohil, Punit; McKee, George R.

    Measurements of long wavelength (kmore » $$\\perp$$p i < 1) density fluctuation characteristics in the edge of both Deuterium (D) and Hydrogen (H) plasmas across the L-H transition on DIII-D demonstrate the existence of single or double bands of low-wavenumber turbulence observed near the edge of H and D plasmas. These are strongly correlated with the L to H-mode transition power threshold (P LH) and can help explain the isotopic and density dependence of P LH, and how the P LH difference is reduced at higher density. Understanding and accurately predicting the L-H power threshold is critical to accessing to H-mode, and operating and achieving high confinement in burning plasmas such as ITER. Above about n e ~ 4 × 10 19 m -3, P LH is seen to converge for H and D, and increases for both with higher density. Surprisingly, the P LH increases significantly at low density in H but not in D plasmas. Two distinct frequency bands of density fluctuations are observed in the D plasmas at low density, n e ~ 1.2-1.5 × 10 19 m -3, but not in H plasmas with similar density, which appears to be correlated to the much lower power threshold in D at low density. Consistently, E × B shear in the region of r/a ~ 0.95-1.0 is larger in D plasmas than in H plasmas at low density; as the P LH increases with increasing density, the dual mode structure disappears while E × B shear becomes similar and small for both D and H plasmas at higher density, n e ~ 5 × 10 19 m -3, where P LH is similar for both D and H plasmas. Lastly, the increased edge fluctuations, increased flow shear, and the dualband nature of edge turbulence correlating with lower P LH may account for the strong isotope and density dependencies of PLH and support current L-H transition theories but suggest a complex behavior that can inform a more complete model of the L-H transition threshold.« less

  18. Turbulence and sheared flow structures behind the isotopic dependence of the L-H power threshold on DIII-D

    DOE PAGES

    Yan, Zheng; Gohil, Punit; McKee, George R.; ...

    2017-09-18

    Measurements of long wavelength (kmore » $$\\perp$$p i < 1) density fluctuation characteristics in the edge of both Deuterium (D) and Hydrogen (H) plasmas across the L-H transition on DIII-D demonstrate the existence of single or double bands of low-wavenumber turbulence observed near the edge of H and D plasmas. These are strongly correlated with the L to H-mode transition power threshold (P LH) and can help explain the isotopic and density dependence of P LH, and how the P LH difference is reduced at higher density. Understanding and accurately predicting the L-H power threshold is critical to accessing to H-mode, and operating and achieving high confinement in burning plasmas such as ITER. Above about n e ~ 4 × 10 19 m -3, P LH is seen to converge for H and D, and increases for both with higher density. Surprisingly, the P LH increases significantly at low density in H but not in D plasmas. Two distinct frequency bands of density fluctuations are observed in the D plasmas at low density, n e ~ 1.2-1.5 × 10 19 m -3, but not in H plasmas with similar density, which appears to be correlated to the much lower power threshold in D at low density. Consistently, E × B shear in the region of r/a ~ 0.95-1.0 is larger in D plasmas than in H plasmas at low density; as the P LH increases with increasing density, the dual mode structure disappears while E × B shear becomes similar and small for both D and H plasmas at higher density, n e ~ 5 × 10 19 m -3, where P LH is similar for both D and H plasmas. Lastly, the increased edge fluctuations, increased flow shear, and the dualband nature of edge turbulence correlating with lower P LH may account for the strong isotope and density dependencies of PLH and support current L-H transition theories but suggest a complex behavior that can inform a more complete model of the L-H transition threshold.« less

  19. In situ Observations of Magnetosonic Waves Modulated by Background Plasma Density

    NASA Astrophysics Data System (ADS)

    Yu, X.; Yuan, Z.; Huang, S.; Wang, D.; Funsten, H. O.

    2017-12-01

    We report in situ observations by the Van Allen Probe mission that magnetosonic (MS) waves are clearly relevant to appear relevant to the background plasma number density. As the satellite moved across dense and tenuous plasma alternatively, MS waves occurred only in lower density region. As the observed protons with 'ring' distributions provide free energy, local linear growth rates are calculated and show that magnetosonic waves can be locally excited in tenuous plasma. With variations of the background plasma density, the temporal variations of local wave growth rates calculated with the observed proton ring distributions, show a remarkable agreement with those of the observed wave amplitude. Therefore, the paper provides a direct proof that background plasma densities can modulate the amplitudes of magnetosonic waves through controlling the wave growth rates.

  20. Detailed analysis of the plasma extracellular vesicle proteome after separation from lipoproteins.

    PubMed

    Karimi, Nasibeh; Cvjetkovic, Aleksander; Jang, Su Chul; Crescitelli, Rossella; Hosseinpour Feizi, Mohammad Ali; Nieuwland, Rienk; Lötvall, Jan; Lässer, Cecilia

    2018-02-13

    The isolation of extracellular vesicles (EVs) from blood is of great importance to understand the biological role of circulating EVs and to develop EVs as biomarkers of disease. Due to the concurrent presence of lipoprotein particles, however, blood is one of the most difficult body fluids to isolate EVs from. The aim of this study was to develop a robust method to isolate and characterise EVs from blood with minimal contamination by plasma proteins and lipoprotein particles. Plasma and serum were collected from healthy subjects, and EVs were isolated by size-exclusion chromatography (SEC), with most particles being present in fractions 8-12, while the bulk of the plasma proteins was present in fractions 11-28. Vesicle markers peaked in fractions 7-11; however, the same fractions also contained lipoprotein particles. The purity of EVs was improved by combining a density cushion with SEC to further separate lipoprotein particles from the vesicles, which reduced the contamination of lipoprotein particles by 100-fold. Using this novel isolation procedure, a total of 1187 proteins were identified in plasma EVs by mass spectrometry, of which several proteins are known as EV-associated proteins but have hitherto not been identified in the previous proteomic studies of plasma EVs. This study shows that SEC alone is unable to completely separate plasma EVs from lipoprotein particles. However, combining SEC with a density cushion significantly improved the separation of EVs from lipoproteins and allowed for a detailed analysis of the proteome of plasma EVs, thus making blood a viable source for EV biomarker discovery.

  1. Poloidal asymmetries in edge transport barriersa)

    NASA Astrophysics Data System (ADS)

    Churchill, R. M.; Theiler, C.; Lipschultz, B.; Hutchinson, I. H.; Reinke, M. L.; Whyte, D.; Hughes, J. W.; Catto, P.; Landreman, M.; Ernst, D.; Chang, C. S.; Hager, R.; Hubbard, A.; Ennever, P.; Walk, J. R.

    2015-05-01

    Measurements of impurities in Alcator C-Mod indicate that in the pedestal region, significant poloidal asymmetries can exist in the impurity density, ion temperature, and main ion density. In light of the observation that ion temperature and electrostatic potential are not constant on a flux surface [Theiler et al., Nucl. Fusion 54, 083017 (2014)], a technique based on total pressure conservation to align profiles measured at separate poloidal locations is presented and applied. Gyrokinetic neoclassical simulations with XGCa support the observed large poloidal variations in ion temperature and density, and that the total pressure is approximately constant on a flux surface. With the updated alignment technique, the observed in-out asymmetry in impurity density is reduced from previous publishing [Churchill et al., Nucl. Fusion 53, 122002 (2013)], but remains substantial ( n z , H / n z , L ˜ 6 ). Candidate asymmetry drivers are explored, showing that neither non-uniform impurity sources nor localized fluctuation-driven transport are able to explain satisfactorily the impurity density asymmetry. Since impurity density asymmetries are only present in plasmas with strong electron density gradients, and radial transport timescales become comparable to parallel transport timescales in the pedestal region, it is suggested that global transport effects relating to the strong electron density gradients in the pedestal are the main driver for the pedestal in-out impurity density asymmetry.

  2. Device and method for relativistic electron beam heating of a high-density plasma to drive fast liners

    DOEpatents

    Thode, Lester E.

    1981-01-01

    A device and method for relativistic electron beam heating of a high-density plasma in a small localized region. A relativistic electron beam generator or accelerator produces a high-voltage electron beam which propagates along a vacuum drift tube and is modulated to initiate electron bunching within the beam. The beam is then directed through a low-density gas chamber which provides isolation between the vacuum modulator and the relativistic electron beam target. The relativistic beam is then applied to a high-density target plasma which typically comprises DT, DD, hydrogen boron or similar thermonuclear gas at a density of 10.sup.17 to 10.sup.20 electrons per cubic centimeter. The target gas is ionized prior to application of the electron beam by means of a laser or other preionization source to form a plasma. Utilizing a relativistic electron beam with an individual particle energy exceeding 3 MeV, classical scattering by relativistic electrons passing through isolation foils is negligible. As a result, relativistic streaming instabilities are initiated within the high-density target plasma causing the relativistic electron beam to efficiently deposit its energy and momentum into a small localized region of the high-density plasma target. Fast liners disposed in the high-density target plasma are explosively or ablatively driven to implosion by a heated annular plasma surrounding the fast liner which is generated by an annular relativistic electron beam. An azimuthal magnetic field produced by axial current flow in the annular plasma, causes the energy in the heated annular plasma to converge on the fast liner.

  3. Nonlinear associations between plasma cholesterol levels and neuropsychological function.

    PubMed

    Wendell, Carrington R; Zonderman, Alan B; Katzel, Leslie I; Rosenberger, William F; Plamadeala, Victoria V; Hosey, Megan M; Waldstein, Shari R

    2016-11-01

    Although both high and low levels of total and low-density lipoprotein (LDL) cholesterol have been associated with poor neuropsychological function, little research has examined nonlinear effects. We examined quadratic relations of cholesterol to performance on a comprehensive neuropsychological battery. Participants were 190 older adults (53% men, ages 54-83) free of major medical, neurologic, and psychiatric disease. Measures of fasting plasma total and high-density lipoprotein (HDL) cholesterol were assayed, and LDL cholesterol was calculated. Participants completed neuropsychological measures of attention, executive function, memory, visuospatial judgment, and manual speed and dexterity. Multiple regression analyses examined cholesterol levels as quadratic predictors of each measure of cognitive performance, with age (dichotomized as <70 vs. 70+) as an effect modifier. A significant quadratic effect of Total Cholesterol² × Age was identified for Logical Memory II ( b = -.0013, p = .039), such that the 70+ group performed best at high and low levels of total cholesterol than at midrange total cholesterol (U-shaped) and the <70 group performed worse at high and low levels of total cholesterol than at midrange total cholesterol (inverted U shape). Similarly, significant U- and J-shaped effects of LDL Cholesterol² × Age were identified for Visual Reproduction II ( b = -.0020, p = .026) and log of the Trail Making Test, Part B (b = .0001, p = .044). Quadratic associations between HDL cholesterol and cognitive performance were nonsignificant. Results indicate differential associations between cholesterol and neuropsychological function across different ages and domains of function. High and low total and LDL cholesterol may confer both risk and benefit for suboptimal cognitive function at different ages. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  4. [Comparative analysis of the lipid-protein spectrum of lipoproteins and fatty acid composition of lipids in plasma and erythrocytes of native populations of Chukotka and Moscow].

    PubMed

    Gerasimova, E N; Levachev, M M; Ozerova, I N; Polesskiĭ, V A; Shcherbakova, I A; Metel'skaia, V A; Kulakova, S N; Astakhova, T I; Nikitin, Iu P; Perova, N V

    1989-01-01

    A lower content of total cholesterol, triglycerides, cholesterol of low density lipoproteins (LDL) and apo B as well as a higher content of cholesterol in high density lipoproteins (HDL) were found in coast and continental Chuckchee land inhabitants as compared with moscowites, which are dissimilar in consumption of polyunsaturated fatty acids n-3. At the same time, the lower content of total cholesterol, LDL cholesterol and higher concentration of HDL cholesterol were detected in blood plasma of coast inhabitants as compared with continental residents of the Chuckchee land, while content of apo B and triglycerides was similar. Concentration of apoA-I was the same in all three groups of the persons examined. The diet of coast Chuchkchee land inhabitants, involving the higher level of unsaturated fatty acids n-3, resulted in the higher ratio between HDL cholesterol and apoA-I, in the higher part of unsaturated fatty acids n-3 in blood plasma lipids (phospholipids and cholesterol esters) and erythrocytes; it led to a relative increase of sphingomyelin and phosphatidyl-ethanolamine and to a decrease of phosphatidylcholine in HDL subfractions. The data obtained suggest that the diet, enriched with polyunsaturated fatty acids n-3, exhibited the generalized effect on fatty acid composition of a number of cell membranes and, hence, on their functions.

  5. Plasma density injection and flow during coaxial helicity injection in a tokamak

    NASA Astrophysics Data System (ADS)

    Hooper, E. B.

    2018-02-01

    Whole device, resistive MHD simulations of spheromaks and tokamaks have used a large diffusion coefficient that maintains a nearly constant density throughout the device. In the present work, helicity and plasma are coinjected into a low-density plasma in a tokamak with a small diffusion coefficient. As in previous simulations [Hooper et al., Phys. Plasmas 20, 092510 (2013)], a flux bubble is formed, which expands to fill the tokamak volume. The injected plasma is non-uniform inside the bubble. The flow pattern is analyzed; when the simulation is not axisymmetric, an n = 1 mode on the surface of the bubble generates leakage of plasma into the low-density volume. Closed flux is generated following injection, as in experiments and previous simulations. The result provides a more detailed physics analysis of the injection, including density non-uniformities in the plasma that may affect its use as a startup plasma [Raman et al., Phys. Rev. Lett. 97, 175002 (2006)].

  6. Investigation of key parameters for the development of reliable ITER baseline operation scenarios using CORSICA

    NASA Astrophysics Data System (ADS)

    Kim, S. H.; Casper, T. A.; Snipes, J. A.

    2018-05-01

    ITER will demonstrate the feasibility of burning plasma operation by operating DT plasmas in the ELMy H-mode regime with a high ratio of fusion power gain Q ~ 10. 15 MA ITER baseline operation scenario has been studied using CORSICA, focusing on the entry to burn, flat-top burning plasma operation and exit from burn. The burning plasma operation for about 400 s of the current flat-top was achieved in H-mode within the various engineering constraints imposed by the poloidal field coil and power supply systems. The target fusion gain (Q ~ 10) was achievable in the 15 MA ITER baseline operation with a moderate amount of the total auxiliary heating power (~50 MW). It has been observed that the tungsten (W) concentration needs to be maintained low level (n w/n e up to the order of 1.0  ×  10-5) to avoid the radiative collapse and uncontrolled early termination of the discharge. The dynamic evolution of the density can modify the H-mode access unless the applied auxiliary heating power is significantly higher than the H-mode threshold power. Several qualitative sensitivity studies have been performed to provide guidance for further optimizing the plasma operation and performance. Increasing the density profile peaking factor was quite effective in increasing the alpha particle self-heating power and fusion power multiplication factor. Varying the combination of auxiliary heating power has shown that the fusion power multiplication factor can be reduced along with the increase in the total auxiliary heating power. As the 15 MA ITER baseline operation scenario requires full capacity of the coil and power supply systems, the operation window for H-mode access and shape modification was narrow. The updated ITER baseline operation scenarios developed in this work will become a basis for further optimization studies necessary along with the improvement in understanding the burning plasma physics.

  7. Electron density measurements in STPX plasmas

    NASA Astrophysics Data System (ADS)

    Clark, Jerry; Williams, R.; Titus, J. B.; Mezonlin, E. D.; Akpovo, C.; Thomas, E.

    2017-10-01

    Diagnostics have been installed to measure the electron density of Spheromak Turbulent Physics Experiment (STPX) plasmas at Florida A. & M. University. An insertable probe, provided by Auburn University, consisting of a combination of a triple-tipped Langmuir probe and a radial array consisting of three ion saturation current / floating potential rings has been installed to measure instantaneous plasma density, temperature and plasma potential. As the ramp-up of the experimental program commences, initial electron density measurements from the triple-probe show that the electron density is on the order of 1019 particles/m3. For a passive measurement, a CO2 interferometer system has been designed and installed for measuring line-averaged densities and to corroborate the Langmuir measurements. We describe the design, calibration, and performance of these diagnostic systems on large volume STPX plasmas.

  8. In vitro studies of PBT Nonwoven Fabrics adsorbent for the removal of low density lipoprotein from hyperlipemia plasma

    NASA Astrophysics Data System (ADS)

    Cao, Ye; Wang, Hong; Yang, Chao; Zhong, Rui; Lei, Yu; Sun, Kang; Liu, Jiaxin

    2011-06-01

    Polyanion ligands such as acrylic acid (AA) and heparin were grafted on PBT Nonwoven Fabrics (PBTNF) to study their effect on the adsorption of low density lipoprotein (LDL). These modified PBTNFs were characterized by Horizontal Attenuated Total Reflectance Fourier Transform Infrared spectroscopy and X-ray Photoelectron spectroscopy. The blood compatibilities of the modified PBTNFs were examined using in vitro hemolysis rate (HR), platelet adhesion, total protein (TP) and activated partial thromboplastin time. The results showed that direct immobilized heparin could improve PBTNF-PAA's blood compatibility and decrease the adsorption capability of useful high density lipoprotein, but would possess so low bioactivity that could not further improve the absorption of LDL and TC. Since the PBTNF-PAA55-Heparin adsorbent had quite good adsorption selectivity for these proteins, it can be an excellent candidate for depletion of LDL with good blood compatibility.

  9. Microwave Interferometric Density Measurements of a Pulsed Helicon Source

    NASA Astrophysics Data System (ADS)

    Scime, Ethan; Scime, Earl; Thompson, Derek

    2017-10-01

    The intense rf environment of a helicon plasma source is problematic for electrostatic probe measurements of plasma density, particularly at low neutral pressures. Here we present measurements of the line-integrated plasma density in a helicon plasma source using a multi-frequency (20-40 GHz) microwave interferometer. The design of the diagnostic and the data acquisition system are presented, as well as a comparison to density profiles obtained with a moveable electrostatic probe. A parametric fit to the probe profile measurements is used to determine the peak density from the microwave density measurements. This work supported by U.S. National Science Foundation Grant No. PHY-1360278.

  10. Electron density measurement in gas discharge plasmas by optical and acoustic methods

    NASA Astrophysics Data System (ADS)

    Biagioni, A.; Anania, M. P.; Bellaveglia, M.; Chiadroni, E.; Cianchi, A.; Di Giovenale, D.; Di Pirro, G.; Ferrario, M.; Filippi, F.; Mostacci, A.; Pompili, R.; Shpakov, V.; Vaccarezza, C.; Villa, F.; Zigler, A.

    2016-08-01

    Plasma density represents a very important parameter for both laser wakefield and plasma wakefield acceleration, which use a gas-filled capillary plasma source. Several techniques can be used to measure the plasma density within a capillary discharge, which are mainly based on optical diagnostic methods, as for example the well-known spectroscopic method using the Stark broadening effect. In this work, we introduce a preliminary study on an alternative way to detect the plasma density, based on the shock waves produced by gas discharge in a capillary. Firstly, the measurements of the acoustic spectral content relative to the laser-induced plasmas by a solid target allowed us to understand the main properties of the acoustic waves produced during this kind of plasma generation; afterwards, we have extended such acoustic technique to the capillary plasma source in order to calibrate it by comparison with the stark broadening method.

  11. Vertical structure of the near-surface expanding ionosphere of comet 67P probed by Rosetta

    NASA Astrophysics Data System (ADS)

    Heritier, K. L.; Henri, P.; Vallières, X.; Galand, M.; Odelstad, E.; Eriksson, A. I.; Johansson, F. L.; Altwegg, K.; Behar, E.; Beth, A.; Broiles, T. W.; Burch, J. L.; Carr, C. M.; Cupido, E.; Nilsson, H.; Rubin, M.; Vigren, E.

    2017-07-01

    The plasma environment has been measured for the first time near the surface of a comet. This unique data set has been acquired at 67P/Churyumov-Gerasimenko during ESA/Rosetta spacecraft's final descent on 2016 September 30. The heliocentric distance was 3.8 au and the comet was weakly outgassing. Electron density was continuously measured with Rosetta Plasma Consortium (RPC)-Mutual Impedance Probe (MIP) and RPC-LAngmuir Probe (LAP) during the descent from a cometocentric distance of 20 km down to the surface. Data set from both instruments have been cross-calibrated for redundancy and accuracy. To analyse this data set, we have developed a model driven by Rosetta Orbiter Spectrometer for Ion and Neutral Analysis-COmetary Pressure Sensor total neutral density. The two ionization sources considered are solar extreme ultraviolet radiation and energetic electrons. The latter are estimated from the RPC-Ion and Electron Sensor (IES) and corrected for the spacecraft potential probed by RPC-LAP. We have compared the results of the model to the electron densities measured by RPC-MIP and RPC-LAP at the location of the spacecraft. We find good agreement between observed and modelled electron densities. The energetic electrons have access to the surface of the nucleus and contribute as the main ionization source. As predicted, the measurements exhibit a peak in the ionospheric density close to the surface. The location and magnitude of the peak are estimated analytically. The measured ionospheric densities cannot be explained with a constant outflow velocity model. The use of a neutral model with an expanding outflow is critical to explain the plasma observations.

  12. Density Structures, Dynamics, and Seasonal and Solar Cycle Modulations of Saturn's Inner Plasma Disk

    NASA Astrophysics Data System (ADS)

    Holmberg, M. K. G.; Shebanits, O.; Wahlund, J.-E.; Morooka, M. W.; Vigren, E.; André, N.; Garnier, P.; Persoon, A. M.; Génot, V.; Gilbert, L. K.

    2017-12-01

    We present statistical results from the Cassini Radio and Plasma Wave Science (RPWS) Langmuir probe measurements recorded during the time interval from orbit 3 (1 February 2005) to 237 (29 June 2016). A new and improved data analysis method to obtain ion density from the Cassini LP measurements is used to study the asymmetries and modulations found in the inner plasma disk of Saturn, between 2.5 and 12 Saturn radii (1 RS=60,268 km). The structure of Saturn's plasma disk is mapped, and the plasma density peak, nmax, is shown to be located at ˜4.6 RS and not at the main neutral source region at 3.95 RS. The shift in the location of nmax is due to that the hot electron impact ionization rate peaks at ˜4.6 RS. Cassini RPWS plasma disk measurements show a solar cycle modulation. However, estimates of the change in ion density due to varying EUV flux is not large enough to describe the detected dependency, which implies that an additional mechanism, still unknown, is also affecting the plasma density in the studied region. We also present a dayside/nightside ion density asymmetry, with nightside densities up to a factor of 2 larger than on the dayside. The largest density difference is found in the radial region 4 to 5 RS. The dynamic variation in ion density increases toward Saturn, indicating an internal origin of the large density variability in the plasma disk rather than being caused by an external source origin in the outer magnetosphere.

  13. Ionising sources in the coma of 67P probed by Rosetta

    NASA Astrophysics Data System (ADS)

    Heritier, Kevin; Galand, Marina; Henri, Pierre; Eriksson, Anders; Odelstad, Elias; Altwegg, Kathrin; Beth, Arnaud; Broiles, Thomas; Burch, Jim; Carr, Christopher; Cupido, Emanuele; Glassmeier, Karl-Heinz; Nilsson, Hans; Richter, Ingo; Rubin, Martin; Vallieres, Xavier; Vigren, Erik

    2017-04-01

    An ionospheric model has been developed in order to quantify the ion number density in the coma of 67P/Churyumov-Gerasimenko. The model is driven by Rosetta Orbiter Spectrometer for Ion and Neutral Analysis (ROSINA)/Cometary Pressure Sensor (COPS) neutral density and assumes isentropic expansion for the neutral density profile. The two ionisation sources considered are photo-ionisation by solar extreme ultraviolet (EUV) radiation and electron-impact ionisation. The EUV radiation is estimated from fluxes measured by the Thermosphere Ionosphere Mesosphere Energetics and Dynamics (TIMED)/ Solar EUV Experiment (SEE), taking into account the phase shift and the heliocentric distance ratio; between Earth and comet 67P. The electron-impact ionisation production rates are derived from Rosetta Plasma Consortium (RPC)-Ion and Electron Sensor (IES) integrated electron fluxes and corrected for the S/C potential from RPC/LAngmuir Probe (LAP) measurements. Our results are compared with in situ measurements of the plasma density from RPC-Mutual Impedance Probe (MIP) and RPC-LAP. There is a good agreement between the modelled and RPC observed electron densities. The ionospheric model enables to distinguish the relative contributions of the different sources to the total cometary plasma. At high heliocentric distances, electron-impact ionisation becomes the dominant ionisation source and is enhanced over the winter hemisphere. As the solar activity has decreased since the beginning of the mission in 2014, the relative importance of photo-ionisation has decreased as well. However, at low heliocentric distances, photo-ionisation seems to be the most dominant ionising source, in particular through the perihelion period in summer 2015.

  14. Oxidation-labile subfraction of human plasma low density lipoprotein isolated by ion-exchange chromatography.

    PubMed

    Shimano, H; Yamada, N; Ishibashi, S; Mokuno, H; Mori, N; Gotoda, T; Harada, K; Akanuma, Y; Murase, T; Yazaki, Y

    1991-05-01

    We isolated subfractions of human plasma low density lipoprotein (LDL) using ion-exchange chromatography. Plasma LDL from normolipidemic subjects were applied to a DEAE Sepharose 6B column. After elution of the bulk of LDL at 150 mM NaCl (the major fraction), the residual LDL was eluted at 500 mM NaCl and designated as the minor fraction. The minor fraction, only less than 1% of total LDL, tended to be somewhat similar in certain properties to oxidized LDL, e.g., an increased negative charge, higher protein/cholesterol ratio, and a higher flotation density than native LDL. These results were consistent with data reported by Avogaro et al. (1988. Arteriosclerosis. 8: 79-87). However, assays of 125I-labeled LDL binding activity for LDL receptors equal to that of the major fraction. Incorporation of [14C]oleate into cholesteryl ester [acyl-CoA:cholesterol acyltransferase (ACAT) activity] in mouse peritoneal macrophages incubated with the minor fraction was only slightly greater than that with the major fraction. Incubation of the minor fraction with 0.5 microM Cu2+ caused a remarkable stimulation of ACAT activity, while stimulation by the major fraction required incubation with 5 microM Cu2+, suggesting that the minor fraction was relatively labile to oxidation. The minor but definite presence of a plasma LDL subfraction more negative and susceptible to oxidation implicates the possibility of its association with atherogenesis.

  15. A Numerical Model of Laser-Induced Fluorescence in a Hydrogen Plasma

    DTIC Science & Technology

    1991-03-10

    cross-sections. Lee, et al., cited screened Coulomb potential calculations by several groups to place an up- per limit of 30 A on the Debye length...intensity: RL(t)(1/sec) = B,,(cir 2/erg . sec) . (J,)(erg/sec .cm -. liz) (3.5) 35 The Einstein coefficients are related by the statistical weights of the...impact processes.) These rate matrices were then added together to obtain the total rate matrix for both groups of electrons. The total electron density

  16. Particle transport in DIII-D plasmas

    NASA Astrophysics Data System (ADS)

    Kress, Peter; Mordijck, Saskia

    2017-10-01

    By analyzing the plasma opacity and density evolution during the ELM cycle in DIII-D H-mode plasmas in which the amount of gas fueling was altered, we find evidence for an inward particle pinch at the plasma edge which seems to become more pronounced at higher density. Furthermore, at the plasma edge we find a correlation between the pedestal density and opacity, which measures neutral penetration depth. The changes in edge opacity during an ELM cycle were calculated by using a detailed time history of measured plasma profiles. At the same time, the density evolution during an ELM cycle was investigated. We find that if the edge density increases through an increase in gas fueling, then opacity increases and neutral fueling penetration depth decreases. We also find that density at the top of the pedestal recovers faster following an ELM when the overall density level is higher, leading to a hollow profile inside of the pedestal top. All these results indicate that there must be an inward particle pinch in the pedestal which will be crucial in the fueling of future burning plasma devices. Supported by US DOE DE-SC0007880, DIII-D Grant Number DE-FC02-04ER54698.

  17. A fully-implicit Particle-In-Cell Monte Carlo Collision code for the simulation of inductively coupled plasmas

    NASA Astrophysics Data System (ADS)

    Mattei, S.; Nishida, K.; Onai, M.; Lettry, J.; Tran, M. Q.; Hatayama, A.

    2017-12-01

    We present a fully-implicit electromagnetic Particle-In-Cell Monte Carlo collision code, called NINJA, written for the simulation of inductively coupled plasmas. NINJA employs a kinetic enslaved Jacobian-Free Newton Krylov method to solve self-consistently the interaction between the electromagnetic field generated by the radio-frequency coil and the plasma response. The simulated plasma includes a kinetic description of charged and neutral species as well as the collision processes between them. The algorithm allows simulations with cell sizes much larger than the Debye length and time steps in excess of the Courant-Friedrichs-Lewy condition whilst preserving the conservation of the total energy. The code is applied to the simulation of the plasma discharge of the Linac4 H- ion source at CERN. Simulation results of plasma density, temperature and EEDF are discussed and compared with optical emission spectroscopy measurements. A systematic study of the energy conservation as a function of the numerical parameters is presented.

  18. Particle-in-cell modeling of laser Thomson scattering in low-density plasmas at elevated laser intensities

    NASA Astrophysics Data System (ADS)

    Powis, Andrew T.; Shneider, Mikhail N.

    2018-05-01

    Incoherent Thomson scattering is a non-intrusive technique commonly used for measuring local plasma density. Within low-density, low-temperature plasmas and for sufficient laser intensity, the laser may perturb the local electron density via the ponderomotive force, causing the diagnostic to become intrusive and leading to erroneous results. A theoretical model for this effect is validated numerically via kinetic simulations of a quasi-neutral plasma using the particle-in-cell technique.

  19. Plasma characteristics of direct current enhanced cylindrical inductively coupled plasma source

    NASA Astrophysics Data System (ADS)

    Yue, HUA; Jian, SONG; Zeyu, HAO; Chunsheng, REN

    2018-06-01

    Experimental results of a direct current enhanced inductively coupled plasma (DCE-ICP) source which consists of a typical cylindrical ICP source and a plate-to-grid DC electrode are reported. With the use of this new source, the plasma characteristic parameters, namely, electron density, electron temperature and plasma uniformity, are measured by Langmuir floating double probe. It is found that DC discharge enhances the electron density and decreases the electron temperature, dramatically. Moreover, the plasma uniformity is obviously improved with the operation of DC and radio frequency (RF) hybrid discharge. Furthermore, the nonlinear enhancement effect of electron density with DC + RF hybrid discharge is confirmed. The presented observation indicates that the DCE-ICP source provides an effective method to obtain high-density uniform plasma, which is desirable for practical industrial applications.

  20. [Study of the effect of heat source separation distance on plasma physical properties in laser-pulsed GMAW hybrid welding based on spectral diagnosis technique].

    PubMed

    Liao, Wei; Hua, Xue-Ming; Zhang, Wang; Li, Fang

    2014-05-01

    In the present paper, the authors calculated the plasma's peak electron temperatures under different heat source separation distance in laser- pulse GMAW hybrid welding based on Boltzmann spectrometry. Plasma's peak electron densities under the corresponding conditions were also calculated by using the Stark width of the plasma spectrum. Combined with high-speed photography, the effect of heat source separation distance on electron temperature and electron density was studied. The results show that with the increase in heat source separation distance, the electron temperatures and electron densities of laser plasma did not changed significantly. However, the electron temperatures of are plasma decreased, and the electron densities of are plasma first increased and then decreased.

  1. Mode conversion at density irregularities in the LAPD

    NASA Astrophysics Data System (ADS)

    Kersten, Kristopher; Cattell, Cynthia; van Compernolle, Bart; Gekelman, Walter; Pribyl, Pat; Vincena, Steve

    2010-11-01

    Mode conversion of electrostatic plasma oscillations to electromagnetic radiation is commonly observed in space plasmas as Type II and III radio bursts. Much theoretical work has addressed the phenomenon, but due to the transient nature and generation location of the bursts, experimental verification via in situ observation has proved difficult. The Large Plasma Device (LAPD) provides a reproducible plasma environment that can be tailored for the study of space plasma phenomena. A highly configurable axial magnetic field and flexible diagnostics make the device well suited for the study of plasma instabilities at density gradients. We present preliminary results of mode conversion studies performed at the LAPD. The studies employed an electron beam source configured to drive Langmuir waves towards high density plasma near the cathode discharge. Internal floating potential probes show the expected plasma oscillations ahead of the beam cathode, and external microwave antenna signals reveal a strong band of radiation near the plasma frequency that persists into the low density plasma afterglow.

  2. Hydrodynamic description of an unmagnetized plasma with multiple ion species. I. General formulation

    DOE PAGES

    Simakov, Andrei Nikolaevich; Molvig, Kim

    2016-03-17

    A generalization of the Braginskii ion fluid description [S. I. Braginskii, Sov. Phys. JETP 6, 358 (1958)] to the case of an unmagnetized collisional plasma with multiple ion species is presented. An asymptotic expansion in the ion Knudsen number is used to derive the individual ion species continuity, as well as the total ion mass density, momentum, and energy evolution equations accurate through the second order. Expressions for the individual ion species drift velocities with respect to the center of mass reference frame, as well as for the total ion heat flux and viscosity, which are required to close themore » fluid equations, are evaluated in terms of the first-order corrections to the lowest order Maxwellian ion velocity distribution functions. A variational formulation for evaluating such corrections and its relation to the plasma entropy are presented. Employing trial functions for the corrections, written in terms of expansions in generalized Laguerre polynomials, and maximizing the resulting functionals produces two systems of linear equations (for “vector” and “tensor” portions of the corrections) for the expansion coefficients. A general matrix formulation of the linear systems as well as expressions for the resulting transport fluxes are presented in forms convenient for numerical implementation. The general formulation is employed in the companion paper [A. N. Simakov and K. Molvig, Hydrodynamic description of an unmagnetized plasma with multiple ion species. II. Two and three ion species plasmas, submitted to Phys. Plasmas (2015)] to evaluate the individual ion drift velocities and the total ion heat flux and viscosity for specific cases of two and three ion species plasmas.« less

  3. Construction of multiple linear regression models using blood biomarkers for selecting against abdominal fat traits in broilers.

    PubMed

    Dong, J Q; Zhang, X Y; Wang, S Z; Jiang, X F; Zhang, K; Ma, G W; Wu, M Q; Li, H; Zhang, H

    2018-01-01

    Plasma very low-density lipoprotein (VLDL) can be used to select for low body fat or abdominal fat (AF) in broilers, but its correlation with AF is limited. We investigated whether any other biochemical indicator can be used in combination with VLDL for a better selective effect. Nineteen plasma biochemical indicators were measured in male chickens from the Northeast Agricultural University broiler lines divergently selected for AF content (NEAUHLF) in the fed state at 46 and 48 d of age. The average concentration of every parameter for the 2 d was used for statistical analysis. Levels of these 19 plasma biochemical parameters were compared between the lean and fat lines. The phenotypic correlations between these plasma biochemical indicators and AF traits were analyzed. Then, multiple linear regression models were constructed to select the best model used for selecting against AF content. and the heritabilities of plasma indicators contained in the best models were estimated. The results showed that 11 plasma biochemical indicators (triglycerides, total bile acid, total protein, globulin, albumin/globulin, aspartate transaminase, alanine transaminase, gamma-glutamyl transpeptidase, uric acid, creatinine, and VLDL) differed significantly between the lean and fat lines (P < 0.01), and correlated significantly with AF traits (P < 0.05). The best multiple linear regression models based on albumin/globulin, VLDL, triglycerides, globulin, total bile acid, and uric acid, had higher R2 (0.73) than the model based only on VLDL (0.21). The plasma parameters included in the best models had moderate heritability estimates (0.21 ≤ h2 ≤ 0.43). These results indicate that these multiple linear regression models can be used to select for lean broiler chickens. © 2017 Poultry Science Association Inc.

  4. Z-Scan Analysis: a New Method to Determine the Oxidative State of Low-Density Lipoprotein and Its Association with Multiple Cardiometabolic Biomarkers

    NASA Astrophysics Data System (ADS)

    de Freitas, Maria Camila Pruper; Figueiredo Neto, Antonio Martins; Giampaoli, Viviane; da Conceição Quintaneiro Aubin, Elisete; de Araújo Lima Barbosa, Milena Maria; Damasceno, Nágila Raquel Teixeira

    2016-04-01

    The great atherogenic potential of oxidized low-density lipoprotein has been widely described in the literature. The objective of this study was to investigate whether the state of oxidized low-density lipoprotein in human plasma measured by the Z-scan technique has an association with different cardiometabolic biomarkers. Total cholesterol, high-density lipoprotein cholesterol, triacylglycerols, apolipoprotein A-I and apolipoprotein B, paraoxonase-1, and glucose were analyzed using standard commercial kits, and low-density lipoprotein cholesterol was estimated using the Friedewald equation. A sandwich enzyme-linked immunosorbent assay was used to detect electronegative low-density lipoprotein. Low-density lipoprotein and high-density lipoprotein sizes were determined by Lipoprint® system. The Z-scan technique was used to measure the non-linear optical response of low-density lipoprotein solution. Principal component analysis and correlations were used respectively to resize the data from the sample and test association between the θ parameter, measured with the Z-scan technique, and the principal component. A total of 63 individuals, from both sexes, with mean age 52 years (±11), being overweight and having high levels of total cholesterol and low levels of high-density lipoprotein cholesterol, were enrolled in this study. A positive correlation between the θ parameter and more anti-atherogenic pattern for cardiometabolic biomarkers together with a negative correlation for an atherogenic pattern was found. Regarding the parameters related with an atherogenic low-density lipoprotein profile, the θ parameter was negatively correlated with a more atherogenic pattern. By using Z-scan measurements, we were able to find an association between oxidized low-density lipoprotein state and multiple cardiometabolic biomarkers in samples from individuals with different cardiovascular risk factors.

  5. Correlations and sum rules in a half-space for a quantum two-dimensional one-component plasma

    NASA Astrophysics Data System (ADS)

    Jancovici, B.; Šamaj, L.

    2007-05-01

    This paper is the continuation of a previous one (Šamaj and Jancovici, 2007 J. Stat. Mech. P02002); for a nearly classical quantum fluid in a half-space bounded by a plain plane hard wall (no image forces), we had generalized the Wigner Kirkwood expansion of the equilibrium statistical quantities in powers of Planck's constant \\hbar . As a model system for a more detailed study, we consider the quantum two-dimensional one-component plasma: a system of charged particles of one species, interacting through the logarithmic Coulomb potential in two dimensions, in a uniformly charged background of opposite sign, such that the total charge vanishes. The corresponding classical system is exactly solvable in a variety of geometries, including the present one of a half-plane, when βe2 = 2, where β is the inverse temperature and e is the charge of a particle: all the classical n-body densities are known. In the present paper, we have calculated the expansions of the quantum density profile and truncated two-body density up to order \\hbar ^2 (instead of only to order \\hbar as in the previous paper). These expansions involve the classical n-body densities up to n = 4; thus we obtain exact expressions for these quantum expansions in this special case. For the quantum one-component plasma, two sum rules involving the truncated two-body density (and, for one of them, the density profile) have been derived, a long time ago, by using heuristic macroscopic arguments: one sum rule concerns the asymptotic form along the wall of the truncated two-body density; the other one concerns the dipole moment of the structure factor. In the two-dimensional case at βe2 = 2, we now have explicit expressions up to order \\hbar^2 for these two quantum densities; thus we can microscopically check the sum rules at this order. The checks are positive, reinforcing the idea that the sum rules are correct.

  6. Beam deviation method as a diagnostic tool for the plasma focus.

    PubMed

    Schmidt, H; Rückle, B

    1978-04-15

    The application of an optical method for density measurements in cylindrical plasmas is described. The angular deviation of a probing light beam sent through a plasma is proportional to the maximum of the density in the plasma column. The deviation does not depend on the plasma dimensions; however, it is influenced to a certain degree by the density profile. The method is successfully applied to the investigation of a dense plasma focus with a time resolution of 2 nsec and a spatial resolution (in axial direction) of 2 mm.

  7. Mitochondria-rich cells adjustments and ionic balance in the Neotropical fish Prochilodus lineatus exposed to titanium dioxide nanoparticles.

    PubMed

    Carmo, Talita L L; Azevedo, Vinícius C; Siqueira, Priscila R; Galvão, Tiago D; Santos, Fabrício A; Martinez, Cláudia B R; Appoloni, Carlos R; Fernandes, Marisa N

    2018-07-01

    Manufactured titanium dioxide nanoparticles (TiO 2 -NP) have been intensely applied in numerous industrial products and may be a risk for aquatic systems as they are not completely removed from domestic and industrial wastes after water treatment. This study evaluated the osmo- and ionic balance, Na + /K + -ATPase, H + -ATPase and carbonic anhydrase activities and the mitochondria-rich cells (MRC) in the gills and kidney of the Neotropical fish Prochilodus lineatus after 2 (acute) and 14 (subchronic) days of exposure to nominal 0, 1, 5, 10 and 50 mg L -1 TiO 2 -NP. The nominal concentrations corresponded to 0.0, 0.6, 1.6, 2.7 and 18.1 mg L -1 suspended TiO 2 -NP, respectively, in the water column one hour after NP introduction and were maintained for at least 24 h. Acute exposure to TiO 2 -NP decreased plasma osmolality and Ca 2+ levels. Na + /K + -ATPase, H + -ATPase and carbonic anhydrase activities were inhibited in the gills, but not in the kidney. Total MRC density did not change in gills and kidneys. At gill surface, total MRC density decreased in fish exposed to 50 mg L -1 TiO 2 -NP and the total MRC fractional surface area unchanged although, there were some changes in the fractional area of MRC with apical microvilli (MRCm) and MRC with apical sponge-like structure (MRCs). MRCm was more abundant than MRCs. After subchronic exposure, there was no change in plasma osmolality, ionic balance and enzyme activities. Total gill MRC density increased in the filament epithelium and renal tubules. In the gills, MRC contacting water exhibited some adjustments. Total MRC and fractional surface area unchanged, but there was an increase of MRCs contacting water at gill surface after exposure to10 and 50 mg L -1 TiO 2 -NP. MRC proliferation in filament epithelium and in renal tubules as well as the increasing MRCs at gill surface may have contributed to avoid change in plasma osmolality, ionic balance and enzyme activities and suggested a cellular physiological and morphological response to restore and maintain osmotic and ionic homeostasis after subchronic exposure. Copyright © 2018 Elsevier B.V. All rights reserved.

  8. Study of electromagnetic wave scattering from an inhomogeneous plasma layer using Green's function volume integral equation method

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Soltanmoradi, Elmira; Shokri, Babak, E-mail: b-shokri@sbu.ac.ir; Laser and Plasma Research Institute, Shahid Beheshti University, G. C., Evin, Tehran 19839-63113

    Gigahertz electromagnetic wave scattering from an inhomogeneous collisional plasma layer with bell-like and Epstein electron density distributions is studied by the Green's function volume integral equation method to find the reflectance, transmittance, and absorbance coefficients of this inhomogeneous plasma. Also, the effects of the frequency of the electromagnetic wave, plasma parameters, such as collision frequency, electron density, and plasma thickness, and the effects of the profile of the electron density on the electromagnetic wave scattering from this plasma slab are investigated. According to the results, when the electron density, collision frequency, and plasma thickness are increased, collisional absorbance is enhanced,more » and as a result, the absorbance bandwidth of plasma is broadened. Moreover, this broadening is more evident for plasma with bell-like electron density profile. Also, the bandwidth of the frequency and the range of pressure in which plasma behaves as a good reflector are determined in this article. According to the results, the bandwidth of the frequency is decreased for thicker plasma with bell-like profile, while it does not vary for a different plasma thickness with Epstein profile. Moreover, the range of the pressure is decreased for bell-like profile in comparison with Epstein profile. Furthermore, due to the sharp inhomogeneity of the Epstein profile, the coefficients of plasma that are uniform for plasma with bell-like profile are changed for plasma with Epstein profile, and some perturbations are seen.« less

  9. Establishment of a low recycling state with full density control by active pumping of the closed helical divertor at LHD

    NASA Astrophysics Data System (ADS)

    Motojima, G.; Masuzaki, S.; Tanaka, H.; Morisaki, T.; Sakamoto, R.; Murase, T.; Tsuchibushi, Y.; Kobayashi, M.; Schmitz, O.; Shoji, M.; Tokitani, M.; Yamada, H.; Takeiri, Y.; The LHD Experiment Group

    2018-01-01

    Superior control of particle recycling and hence full governance of plasma density has been established in the Large Helical Device (LHD) using largely enhanced active pumping of the closed helical divertor (CHD). In-vessel cryo-sorption pumping systems inside the CHD in five out of ten inner toroidal divertor sections have been developed and installed step by step in the LHD. The total effective pumping speed obtained was 67  ±  5 m3 s-1 in hydrogen, which is approximately seven times larger than previously obtained. As a result, a low recycling state was observed with CHD pumping for the first time in LHD featuring excellent density control even under intense pellet fueling conditions. A global particle confinement time (τ p* ) is used for comparison of operation with and without the CHD pumping. The τ p* was evaluated from the density decay after the fueling of hydrogen pellet injection or gas puffing in NBI plasmas. A reliably low base density before the fueling and short τ p* after the fueling were obtained during the CHD pumping, demonstrating for the first time full control of the particle balance with active pumping in the CHD.

  10. Research progress on ionic plasmas generated in an intense hydrogen negative ion source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Takeiri, Y., E-mail: takeiri@nifs.ac.jp; Tsumori, K.; Nagaoka, K.

    2015-04-08

    Characteristics of ionic plasmas, observed in a high-density hydrogen negative ion source, are investigated with a multi-diagnostics system. The ionic plasma, which consists of hydrogen positive- and negative-ions with a significantly low-density of electrons, is generated in the ion extraction region, from which the negative ions are extracted through the plasma grid. The negative ion density, i.e., the ionic plasma density, as high as the order of 1×10{sup 17}m{sup −3}, is measured with cavity ring-down spectroscopy, while the electron density is lower than 1×10{sup 16}m{sup −3}, which is confirmed with millimeter-wave interferometer. Reduction of the negative ion density is observedmore » at the negative ion extraction, and at that time the electron flow into the ionic plasma region is observed to conserve the charge neutrality. Distribution of the plasma potential is measured in the extraction region in the direction normal to the plasma grid surface with a Langmuir probe, and the results suggest that the sheath is formed at the plasma boundary to the plasma grid to which the bias voltage is applied. The beam extraction should drive the negative ion transport in the ionic plasma across the sheath formed on the extraction surface. Larger reduction of the negative ions at the beam extraction is observed in a region above the extraction aperture on the plasma grid, which is confirmed with 2D image measurement of the Hα emission and cavity ring-down spectroscopy. The electron distribution is also measured near the plasma grid surface. These various properties observed in the ionic plasma are discussed.« less

  11. Effect of cathode cooling efficiency and oxygen plasma gas pressure on the hafnium cathode wall temperature

    NASA Astrophysics Data System (ADS)

    Ashtekar, Koustubh; Diehl, Gregory; Hamer, John

    2012-10-01

    The hafnium cathode is widely used in DC plasma arc cutting (PAC) under an oxygen gas environment to cut iron and iron alloys. The hafnium erosion is always a concern which is controlled by the surface temperature. In this study, the effect of cathode cooling efficiency and oxygen gas pressure on the hafnium surface temperature are quantified. The two layer cathode sheath model is applied on the refractive hafnium surface while oxygen species (O2, O, O+, O++, e-) are considered within the thermal dis-equilibrium regime. The system of non-linear equations comprising of current density balance, heat flux balance at both the cathode surface and the sheath-ionization layer is coupled with the plasma gas composition solver. Using cooling heat flux, gas pressure and current density as inputs; the cathode wall temperature, electron temperature, and sheath voltage drop are calculated. Additionally, contribution of emitted electron current (Je) and ions current (Ji) to the total current flux are estimated. Higher gas pressure usually reduces Ji and increases Je that reduces the surface temperature by thermionic cooling.

  12. Enhancement of axial momentum lost to the radial wall by the upstream magnetic field in a helicon source

    NASA Astrophysics Data System (ADS)

    Takahashi, Kazunori; Ando, Akira

    2017-05-01

    Individual measurements of forces exerted to an upstream back wall, a radial source wall, and a magnetic field of a helicon plasma thruster, which has two solenoids upstream and downstream of a radiofrequency antenna, are precisely measured. Two different structures of magnetic field lines in the source are tested, where the solenoid current is supplied to either only the downstream solenoid or to both the solenoids. It is observed that the high density plasma exists upstream of the rf antenna when both the solenoids are powered, while the maximum density exists near the rf antenna when only the downstream solenoid is powered. Although the force exerted to the back wall is increased for the two solenoids case, the axial momentum lost to the radial wall is simultaneously enhanced; then the total force exerted to the whole structure of the thruster is found to be very similar for the two magnetic field configurations. It is shown that the individual force measurement provides useful information on the plasma momentum interacting with the physical boundaries and the magnetic fields.

  13. High density operation with Lower Hybrid waves in FTU tokamak

    NASA Astrophysics Data System (ADS)

    Pericoli Ridolfini, V.; Mirizzi, F.; Panaccione, L.; Podda, S.

    2001-10-01

    Since April 2001 the lower hybrid (LH) radiofrequency system in FTU (6 gyrotrons @ f=8 GHz) can deliver to the plasma about 2 MW through two equal launchers with a reflection coefficient = 10%. This value is close to the target value of 2.2 MW (net power density of 6.2 kW/cm2 on the waveguides mouth) which could be reached after further conditioning of the grill and of the transmission lines. In high density plasmas (line density *1*1020 m-3), high magnetic field (BT=7.2 T), with PLH=2 MW we drive about 75% of the total current (Ip=500 kA) and stabilise fully the sawteeth activity. The central electron temperature Te0 increases from 1.6 to 3.3 keV (steady), and the neutron rate by about 10 times. Analysis of these pulses with effective electronic heating will be presented. In post-pellet plasmas ( *6*1020 m-3), good coupling of the LH is achieved with the launcher almost flush to the walls, due to the very dense scrape off-layer. The perturbation here induced by the pellet imposes a delay to the LH of only 20 ms. The exact location of the launcher is critical in these regimes, because the high N|| (parallel index of refraction) requested (N||>2.3) for a good penetration of the waves makes more problematic a good coupling all along the poloidal extension of the grill.

  14. Third harmonic generation of a short pulse laser in a plasma density ripple created by a machining beam

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, C. S.; Tripathi, V. K.

    An intense machining laser beam, impinged on a gas jet target, causes space periodic ionization of the gas and heats the electrons. The nonuniform plasma pressure leads to atomic density redistribution. When, after a suitable time delay, a second more intense laser pulse is launched along the periodicity wave vector q-vector, a plasma density ripple n{sub q} is instantly created, leading to resonant third harmonic generation when q=4{omega}{sub p}{sup 2}/(3{omega}c{gamma}{sub 0}), where {omega}{sub p} is the plasma frequency, {omega} is the laser frequency, and {gamma}{sub 0} is the electron Lorentz factor. The third harmonic is produced through the beating ofmore » ponderomotive force induced second harmonic density oscillations and the quiver velocity of electrons at the fundamental. The relativistic mass nonlinearity plays no role in resonant coupling. The energy conversion efficiency scales as the square of plasma density and square of depth of density ripple, and is {approx}0.2% for normalized laser amplitude a{sub o}{approx}1 in a plasma of 1% critical density with 20% density ripple. The theory explains several features of a recent experiment.« less

  15. Solar wind thermal electrons in the ecliptic plane between 1 and 4 AU - Preliminary results from the Ulysses radio receiver

    NASA Technical Reports Server (NTRS)

    Hoang, S.; Meyer-Vernet, N.; Bougeret, J.-L.; Harvey, C. C.; Lacombe, C.; Mangeney, A.; Moncuquet, M.; Perche, C.; Steinberg, J.-L.; Macdowall, R. J.

    1992-01-01

    The radio receiver of the Unified Radio and Plasma experiment aboard the Ulysses spacecraft records spectra of the quasi-thermal plasma noise. The interpretation of these spectra allows the determination of the total electron density Ne and of the cold (core) electron temperature Tc in the solar wind. A single power law does not fit the variations of Ne which result from the contribution from different solar wind structures. The distribution of the values of Tc suggests that, on the average, the solar wind is nearly isothermal.

  16. Hydrodynamic description of an unmagnetized plasma with multiple ion species. I. General formulation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Simakov, Andrei N., E-mail: simakov@lanl.gov; Molvig, Kim

    2016-03-15

    A generalization of the Braginskii ion fluid description [S. I. Braginskii, Sov. Phys. - JETP 6, 358 (1958)] to the case of an unmagnetized collisional plasma with multiple ion species is presented. An asymptotic expansion in the ion Knudsen number is used to derive the individual ion species continuity, as well as the total ion mass density, momentum, and energy evolution equations accurate through the second order. Expressions for the individual ion species drift velocities with respect to the center of mass reference frame, as well as for the total ion heat flux and viscosity, which are required to closemore » the fluid equations, are evaluated in terms of the first-order corrections to the lowest order Maxwellian ion velocity distribution functions. A variational formulation for evaluating such corrections and its relation to the plasma entropy are presented. Employing trial functions for the corrections, written in terms of expansions in generalized Laguerre polynomials, and maximizing the resulting functionals produce two systems of linear equations (for “vector” and “tensor” portions of the corrections) for the expansion coefficients. A general matrix formulation of the linear systems as well as expressions for the resulting transport fluxes are presented in forms convenient for numerical implementation. The general formulation is employed in Paper II [A. N. Simakov and K. Molvig, Phys. Plasmas 23, 032116 (2016)] to evaluate the individual ion drift velocities and the total ion heat flux and viscosity for specific cases of two and three ion species plasmas.« less

  17. Comparison of surface vacuum ultraviolet emissions with resonance level number densities. II. Rare-gas plasmas and Ar-molecular gas mixtures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Boffard, John B., E-mail: jboffard@wisc.edu; Lin, Chun C.; Wang, Shicong

    2015-03-15

    Vacuum ultraviolet (VUV) emissions from excited plasma species can play a variety of roles in processing plasmas, including damaging the surface properties of materials used in semiconductor processing. Depending on their wavelength, VUV photons can easily transmit thin upper dielectric layers and affect the electrical characteristics of the devices. Despite their importance, measuring VUV fluxes is complicated by the fact that few materials transmit at VUV wavelengths, and both detectors and windows are easily damaged by plasma exposure. The authors have previously reported on measuring VUV fluxes in pure argon plasmas by monitoring the concentrations of Ar(3p{sup 5}4s) resonance atomsmore » that produce the VUV emissions using noninvasive optical emission spectroscopy in the visible/near-infrared wavelength range [Boffard et al., J. Vac. Sci. Technol., A 32, 021304 (2014)]. Here, the authors extend this technique to other rare-gases (Ne, Kr, and Xe) and argon-molecular gas plasmas (Ar/H{sub 2}, Ar/O{sub 2}, and Ar/N{sub 2}). Results of a model for VUV emissions that couples radiation trapping and the measured rare-gas resonance level densities are compared to measurements made with both a calibrated VUV photodiode and a sodium salicylate fluorescence detection scheme. In these more complicated gas mixtures, VUV emissions from a variety of sources beyond the principal resonance levels of the rare gases are found to contribute to the total VUV flux.« less

  18. Spatial distribution of the RF power absorbed in a helicon plasma source

    NASA Astrophysics Data System (ADS)

    Aleksenko, O. V.; Miroshnichenko, V. I.; Mordik, S. N.

    2014-08-01

    The spatial distributions of the RF power absorbed by plasma electrons in an ion source operating in the helicon mode (ω ci < ω < ω ce < ω pe ) are studied numerically by using a simplified model of an RF plasma source in an external uniform magnetic field. The parameters of the source used in numerical simulations are determined by the necessity of the simultaneous excitation of two types of waves, helicons and Trivelpiece-Gould modes, for which the corresponding transparency diagrams are used. The numerical simulations are carried out for two values of the working gas (helium) pressure and two values of the discharge chamber length under the assumption that symmetric modes are excited. The parameters of the source correspond to those of the injector of the nuclear scanning microprobe operating at the Institute of Applied Physics, National Academy of Sciences of Ukraine. It is assumed that the mechanism of RF power absorption is based on the acceleration of plasma electrons in the field of a Trivelpiece-Gould mode, which is interrupted by pair collisions of plasma electrons with neutral atoms and ions of the working gas. The simulation results show that the total absorbed RF power at a fixed plasma density depends in a resonant manner on the magnetic field. The resonance is found to become smoother with increasing working gas pressure. The distributions of the absorbed RF power in the discharge chamber are presented. The achievable density of the extracted current is estimated using the Bohm criterion.

  19. Structured DC Electric Fields With and Without Associated Plasma Density Gradients Observed with the C/NOFS Satellite

    NASA Technical Reports Server (NTRS)

    Pfaff, R.; Rowland, D.; Klenzing, J.; Freudenreich, H.; Bromund, K.; Liebrecht, C.; Roddy, P.; Hunton, D.

    2009-01-01

    DC electric field observations and associated plasma drifts gathered with the Vector Electric Field Investigation on the Air Force Communication/Navigation Outage Forecasting System (C/NOFS) satellite typically reveal considerable variation at large scales (approximately 100's of km), in both daytime and nighttime cases, with enhanced structures usually confined to the nightside. Although such electric field structures are typically associated with plasma density depletions and structures, as observed by the Planar Langmuir Probe on C/NOFS, what is surprising is the number of cases in which large amplitude, structured DC electric fields are observed without a significant plasma density counterpart structure, including their appearance at times when the ambient plasma density appears relatively quiescent. We investigate the relationship of such structured DC electric fields and the ambient plasma density in the C/NOFS satellite measurements observed thus far, taking into account both plasma density depletions and enhancements. We investigate the mapping of the electric fields along magnetic field lines from distant altitudes and latitudes to locations where the density structures, which presumably formed the original seat of the electric fields, are no longer discernible in the observations. In some cases, the electric field structures and spectral characteristics appear to mimic those associated with equatorial spread-F processes, providing important clues to their origins. We examine altitude, seasonal, and longitudinal effects in an effort to establish the origin of such structured DC electric fields observed both with, and without, associated plasma density gradients

  20. Electron density measurement of non-equilibrium atmospheric pressure plasma using dispersion interferometer

    NASA Astrophysics Data System (ADS)

    Yoshimura, Shinji; Kasahara, Hiroshi; Akiyama, Tsuyoshi

    2017-10-01

    Medical applications of non-equilibrium atmospheric plasmas have recently been attracting a great deal of attention, where many types of plasma sources have been developed to meet the purposes. For example, plasma-activated medium (PAM), which is now being studied for cancer treatment, has been produced by irradiating non-equilibrium atmospheric pressure plasma with ultrahigh electron density to a culture medium. Meanwhile, in order to measure electron density in magnetic confinement plasmas, a CO2 laser dispersion interferometer has been developed and installed on the Large Helical Device (LHD) at the National Institute for Fusion Science, Japan. The dispersion interferometer has advantages that the measurement is insensitive to mechanical vibrations and changes in neutral gas density. Taking advantage of these properties, we applied the dispersion interferometer to electron density diagnostics of atmospheric pressure plasmas produced by the NU-Global HUMAP-WSAP-50 device, which is used for producing PAM. This study was supported by the Grant of Joint Research by the National Institutes of Natural Sciences (NINS).

  1. Stability of an ion-ring distribution in a multi-ion component plasma

    NASA Astrophysics Data System (ADS)

    Mithaiwala, Manish; Rudakov, Leonid; Ganguli, Gurudas

    2010-04-01

    The stability of a cold ion-ring velocity distribution in a thermal plasma is analyzed. In particular, the effect of plasma temperature and density on the instability is considered. A high ring density (compared to the background plasma) neutralizes the stabilizing effect of the warm background plasma and the ring is unstable to the generation of waves below the lower-hybrid frequency even for a very high temperature plasma. For ring densities lower than the background plasma density, there is a slow instability where the growth rate is less than the background-ion cyclotron frequency and, consequently, the background-ion response is magnetized. This is in addition to the widely discussed fast instability where the wave growth rate exceeds the background-ion cyclotron frequency and hence the background ions are effectively unmagnetized. Thus, even a low density ring is unstable to waves around the lower-hybrid frequency range for any ring speed. This implies that effectively there is no velocity threshold for a sufficiently cold ring.

  2. Temperature of the plasmasphere from Van Allen Probes HOPE

    NASA Astrophysics Data System (ADS)

    Genestreti, K. J.; Goldstein, J.; Corley, G. D.; Farner, W.; Kistler, L. M.; Larsen, B. A.; Mouikis, C. G.; Ramnarace, C.; Skoug, R. M.; Turner, N. E.

    2017-01-01

    We introduce two novel techniques for estimating temperatures of very low energy space plasmas using, primarily, in situ data from an electrostatic analyzer mounted on a charged and moving spacecraft. The techniques are used to estimate proton temperatures during intervals where the bulk of the ion plasma is well below the energy bandpass of the analyzer. Both techniques assume that the plasma may be described by a one-dimensional E→×B→ drifting Maxwellian and that the potential field and motion of the spacecraft may be accounted for in the simplest possible manner, i.e., by a linear shift of coordinates. The first technique involves the application of a constrained theoretical fit to a measured distribution function. The second technique involves the comparison of total and partial-energy number densities. Both techniques are applied to Van Allen Probes Helium, Oxygen, Proton, and Electron (HOPE) observations of the proton component of the plasmasphere during two orbits on 15 January 2013. We find that the temperatures calculated from these two order-of-magnitude-type techniques are in good agreement with typical ranges of the plasmaspheric temperature calculated using retarding potential analyzer-based measurements—generally between 0.2 and 2 eV (2000-20,000 K). We also find that the temperature is correlated with L shell and hot plasma density and is negatively correlated with the cold plasma density. We posit that the latter of these three relationships may be indicative of collisional or wave-driven heating of the plasmasphere in the ring current overlap region. We note that these techniques may be easily applied to similar data sets or used for a variety of purposes.

  3. Turbulence and sheared flow structures behind the isotopic dependence of the L-H power threshold on DIII-D

    NASA Astrophysics Data System (ADS)

    Yan, Z.; Gohil, P.; McKee, G. R.; Eldon, D.; Grierson, B.; Rhodes, T.; Petty, C. C.

    2017-12-01

    Measurements of long wavelength ({{k}\\bot }{{ρ }i}   <  1) density fluctuation characteristics in the edge of both Deuterium (D) and Hydrogen (H) plasmas across the L-H transition on DIII-D demonstrate the existence of single or double bands of low-wavenumber turbulence observed near the edge of H and D plasmas. These are strongly correlated with the L to H-mode transition power threshold (P LH) and can help explain the isotopic and density dependence of P LH, and how the P LH difference is reduced at higher density. Understanding and accurately predicting the L-H power threshold is critical to accessing to H-mode, and operating and achieving high confinement in burning plasmas such as ITER. Above about n e ~ 4  ×  1019 m-3, P LH is seen to converge for H and D, and increases for both with higher density. Surprisingly, the P LH increases significantly at low density in H but not in D plasmas. Two distinct frequency bands of density fluctuations are observed in the D plasmas at low density, n e ~ 1.2-1.5  ×  1019 m-3, but not in H plasmas with similar density, which appears to be correlated to the much lower power threshold in D at low density. Consistently, E  ×  B shear in the region of r/a ~ 0.95-1.0 is larger in D plasmas than in H plasmas at low density; as the P LH increases with increasing density, the dual mode structure disappears while E  ×  B shear becomes similar and small for both D and H plasmas at higher density, n e ~ 5  ×  1019 m-3, where P LH is similar for both D and H plasmas. The increased edge fluctuations, increased flow shear, and the dual-band nature of edge turbulence correlating with lower P LH may account for the strong isotope and density dependencies of P LH and support current L-H transition theories but suggest a complex behavior that can inform a more complete model of the L-H transition threshold.

  4. Capacitive radio frequency discharges with a single ring-shaped narrow trench of various depths to enhance the plasma density and lateral uniformity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ohtsu, Y., E-mail: ohtsuy@cc.saga-u.ac.jp; Matsumoto, N.; Schulze, J.

    2016-03-15

    Spatial structures of the electron density and temperature in ring-shaped hollow cathode capacitive rf plasma with a single narrow trench of 2 mm width have been investigated at various trench depths of D = 5, 8, 10, 12, and 15 mm. It is found that the plasma density is increased in the presence of the trench and that the radial profile of the plasma density has a peak around the narrow hollow trench near the cathode. The density becomes uniform further away from the cathode at all trench depths, whereas the electron temperature distribution remains almost uniform. The measured radial profiles of the plasmamore » density are in good agreement with a theoretical diffusion model for all the trench depths, which explains the local density increase by a local enhancement of the electron heating. Under the conditions investigated, the trench of 10 mm depth is found to result in the highest plasma density at various axial and radial positions. The results show that the radial uniformity of the plasma density at various axial positions can be improved by using structured electrodes of distinct depths rather than planar electrodes.« less

  5. Modeling ionospheric pre-reversal enhancement and plasma bubble growth rate using data assimilation

    NASA Astrophysics Data System (ADS)

    Rajesh, P. K.; Lin, C. C. H.; Chen, C. H.; Matsuo, T.

    2017-12-01

    We report that assimilating total electron content (TEC) into a coupled thermosphere-ionosphere model by using the ensemble Kalman filter results in improved specification and forecast of eastward pre-reversal enhancement (PRE) electric field (E-field). Through data assimilation, the ionospheric plasma density, thermospheric winds, temperature and compositions are adjusted simultaneously. The improvement of dusk-side PRE E-field over the prior state is achieved primarily by intensification of eastward neutral wind. The improved E-field promotes a stronger plasma fountain and deepens the equatorial trough. As a result, the horizontal gradients of Pedersen conductivity and eastward wind are increased due to greater zonal electron density gradient and smaller ion drag at dusk, respectively. Such modifications provide preferable conditions and obtain a strengthened PRE magnitude closer to the observation. The adjustment of PRE E-field is enabled through self-consistent thermosphere and ionosphere coupling processes captured in the model. The assimilative outputs are further utilized to calculate the flux tube integrated Rayleigh-Taylor instability growth rate during March 2015 for investigation of global plasma bubble occurrence. Significant improvements in the calculated growth rates could be achieved because of the improved update of zonal electric field in the data assimilation forecast. The results suggest that realistic estimate or prediction of plasma bubble occurrence could be feasible by taking advantage of the data assimilation approach adopted in this work.

  6. Study of the phosphine plasma decomposition and its formation by ablation of red phosphorus in hydrogen plasma

    NASA Astrophysics Data System (ADS)

    Bruno, G.; Losurdo, M.; Capezzuto, P.

    1995-03-01

    Mass spectrometry and optical emission spectroscopy have been used to study the chemistry of PH(sub 3) plasma decomposition as well as its formation by ablation of red phosphorus in hydrogen plasma. It has been shown that PH(sub 3) decomposition easily equilibrates at low levels of PH(sub 3) depletion (15%-30%), this depending mainly on the rf power. The ablation of red phosphorus in H(sub 2) plasma produces phosphine in significant amount, depending mainly on the total pressure but also on the rf power. It has also been found that H(sup *) and PH(sup *) emitting species originate not only by the dissociative excitation of H(sub 2) and PH(sub 3), respectively, but also by the direct excitation of the same species in the ground state. Considerations are developed on how to derive the H-atom and PH radical densities by actinometry, under specific experimental conditions. Besides, the linear dependence of PH(sub 3) formation rate, r(sub PH(3)), on H-atom density, (left bracket) H (right bracket), leads to the definition of the kinetic equation r(sub PH(3)) = k (left bracket) H (right bracket), and to the hypothesis that the formation of PH radical on the surface or its desorption is the dominant mechanism for PH(sub 3) production.

  7. Implementation of an Unequal Path Length, Heterodyne Interferometer on the MOCHI LabJet Experiment

    NASA Astrophysics Data System (ADS)

    Card, Alexander Harrison

    The MOCHI LabJet experiment aims to explore the stability of magnetic flux tubes through the medium of laboratory astrophysical plasmas. The boundary conditions of large gravitational bodies, namely accretion disks, are replicated and allowed to influence a plasma over short timescales. Observation of the plasma is enabled through use of a variety of fast diagnostics, including an unequal path length, heterodyne, quadrature phase differential interferometer, the development and implementation of which is described in detail. The LabJet gun, a triple-electrode planar plasma gun featuring azimuthally symmetric gas injection achieves a new, long-duration, highly-stabilized, jet plasma formation. The line-integrated density in this new LabJet formation is found to be ne = (6 +/- 3)x1020 [m-2]. By observing the axial expansion rate of the jet over multiple chord locations (all perpendicular to the propagation axis), the interferometer provides an Alfvén velocity measurement of vA = 41.3 +/- 5.4 [km/s], which at the jet density observed indicates an axial magnetic field strength of Bz = 0.15 +/- 0.04 [T]. Various other laboratory components are also detailed, such as a shot-based MDSplus data storage architecture implemented into the LabVIEW experiment control code, and the production and performance of ten fast neutral gas injection valves which when fired in unison provide a total particle inventory of (7.8 +/- 0.6)x1023 [HI particles].

  8. ADX: A high Power Density, Advanced RF-Driven Divertor Test Tokamak for PMI studies

    NASA Astrophysics Data System (ADS)

    Whyte, Dennis; ADX Team

    2015-11-01

    The MIT PSFC and collaborators are proposing an advanced divertor experiment, ADX; a divertor test tokamak dedicated to address critical gaps in plasma-material interactions (PMI) science, and the world fusion research program, on the pathway to FNSF/DEMO. Basic ADX design features are motivated and discussed. In order to assess the widest range of advanced divertor concepts, a large fraction (>50%) of the toroidal field volume is purpose-built with innovative magnetic topology control and flexibility for assessing different surfaces, including liquids. ADX features high B-field (>6 Tesla) and high global power density (P/S ~ 1.5 MW/m2) in order to access the full range of parallel heat flux and divertor plasma pressures foreseen for reactors, while simultaneously assessing the effect of highly dissipative divertors on core plasma/pedestal. Various options for efficiently achieving high field are being assessed including the use of Alcator technology (cryogenic cooled copper) and high-temperature superconductors. The experimental platform would also explore advanced lower hybrid current drive and ion-cyclotron range of frequency actuators located at the high-field side; a location which is predicted to greatly reduce the PMI effects on the launcher while minimally perturbing the core plasma. The synergistic effects of high-field launchers with high total B on current and flow drive can thus be studied in reactor-relevant boundary plasmas.

  9. Observation of helicon wave with m = 0 antenna in a weakly magnetized inductively coupled plasma source

    NASA Astrophysics Data System (ADS)

    Ellingboe, Bert; Sirse, Nishant; Moloney, Rachel; McCarthy, John

    2015-09-01

    Bounded whistler wave, called ``helicon wave,'' is known to produce high-density plasmas and has been exploited as a high density plasma source for many applications, including electric propulsion for spacecraft. In a helicon plasma source, an antenna wrapped around the magnetized plasma column launches a low frequency wave, ωce/2 >ωhelicon >ωce/100, in the plasma which is responsible for maintaining high density plasma. Several antenna designs have been proposed in order to match efficiently the wave modes. In our experiment, helicon wave mode is observed using an m = 0 antenna. A floating B dot probe, compensated to the capacitively coupled E field, is employed to measure axial-wave-field-profiles (z, r, and θ components) in the plasma at multiple radial positions as a function of rf power and pressure. The Bθ component of the rf-field is observed to be unaffected as the wave propagates in the axial direction. Power coupling between the antenna and the plasma column is identified and agrees with the E, H, and wave coupling regimes previously seen in M =1 antenna systems. That is, the Bz component of the rf-field is observed at low plasma density as the Bz component from the antenna penetrates the plasma. The Bz component becomes very small at medium density due to shielding at the centre of the plasma column; however, with increasing density, a sudden ``jump'' occurs in the Bz component above which a standing wave under the antenna with a propagating wave away from the antenna are observed.

  10. Influence of Plasma Unsteadiness on the Spectrum and Shape of Microwave Pulses in a Plasma Relativistic Microwave Amplifier

    NASA Astrophysics Data System (ADS)

    Kartashov, I. N.; Kuzelev, M. V.; Strelkov, P. S.; Tarakanov, V. P.

    2018-02-01

    Dependence of the shape of a microwave pulse in a plasma relativistic microwave amplifier (PRMA) on the initial plasma electron density in the system is detected experimentally. Depending on the plasma density, fast disruption of amplification, stable operation of the amplifier during the relativistic electron beam (REB) pulse, and its delayed actuation can take place. A reduction in the output signal frequency relative to the input frequency is observed experimentally. The change in the shape of the microwave signal and the reduction in its frequency are explained by a decrease in the plasma density in the system. The dynamics of the plasma density during the REB pulse is determined qualitatively from the experimental data by using the linear theory of a PRMA with a thin-wall hollow electron beam. The processes in a PRMA are analyzed by means of the KARAT particle-in-cell code. It is shown that REB injection is accompanied by an increase in the mean energy of plasma electrons and a significant decrease in their density.

  11. Modeling plasma-assisted growth of graphene-carbon nanotube hybrid

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tewari, Aarti

    2016-08-15

    A theoretical model describing the growth of graphene-CNT hybrid in a plasma medium is presented. Using the model, the growth of carbon nanotube (CNT) on a catalyst particle and thereafter the growth of the graphene on the CNT is studied under the purview of plasma sheath and number density kinetics of different plasma species. It is found that the plasma parameter such as ion density; gas ratios and process parameter such as source power affect the CNT and graphene dimensions. The variation in growth rates of graphene and CNT under different plasma power, gas ratios, and ion densities is analyzed.more » Based on the results obtained, it can be concluded that higher hydrocarbon ion densities and gas ratios of hydrocarbon to hydrogen favor the growth of taller CNTs and graphene, respectively. In addition, the CNT tip radius reduces with hydrogen ion density and higher plasma power favors graphene with lesser thickness. The present study can help in better understanding of the graphene-CNT hybrid growth in a plasma medium.« less

  12. Injection of auxiliary electrons for increasing the plasma density in highly charged and high intensity ion sources.

    PubMed

    Odorici, F; Malferrari, L; Montanari, A; Rizzoli, R; Mascali, D; Castro, G; Celona, L; Gammino, S; Neri, L

    2016-02-01

    Different electron guns based on cold- or hot-cathode technologies have been developed since 2009 at INFN for operating within ECR plasma chambers as sources of auxiliary electrons, with the aim of boosting the source performances by means of a higher plasma lifetime and density. Their application to microwave discharge ion sources, where plasma is not confined, has required an improvement of the gun design, in order to "screen" the cathode from the plasma particles. Experimental tests carried out on a plasma reactor show a boost of the plasma density, ranging from 10% to 90% when the electron guns are used, as explained by plasma diffusion models.

  13. Plasma influence on the dispersion properties of finite-length, corrugated waveguides

    NASA Astrophysics Data System (ADS)

    Shkvarunets, A.; Kobayashi, S.; Weaver, J.; Carmel, Y.; Rodgers, J.; Antonsen, T. M., Jr.; Granatstein, V. L.; Destler, W. W.; Ogura, K.; Minami, K.

    1996-03-01

    We present an experimental study of the electromagnetic properties of transverse magnetic modes in a corrugated-wall cavity filled with a radially inhomogeneous plasma. The shifts of the resonant frequencies of a finite-length, corrugated cavity were measured as a function of the background plasma density and the dispersion diagram was reconstructed up to a peak plasma density of 1012 cm-3. Good agreement with a calculated dispersion diagram is obtained for plasma densities below 5×1011 cm-3.

  14. Plasma and semen ascorbic levels in spermatogenesis.

    PubMed

    Ebesunun, M O; Solademi, B A; Shittu, O B; Anetor, J I; Onuegbu, J A; Olisekodiaka, J M; Agbedana, E O; Onyeaghala, A A

    2004-01-01

    Conflicting reports on the mechanism of action of ascorbic acid level in male reproductive system exist and very little is known about the ascorbic acid status in Nigerian males with weak fertility. Ascorbate that accumulates preferentially in the testis, the lipid and lipoprotein levels were determined in the plasma of Nigerian males. Twenty-seven (27) male with inadequate spermatogenesis (36+/-1.0) years, with mean value of 15.6+/-6.90 million/cm3 sperm count and fourteen (14) controls (34+/-0.6) years, with mean value of 108.0+/-25.42 million/cm3 sperm count were selected for this study. The anthropometric indices were also determined. There were highly significant decreases in sperm cell count, percentage motility and percentage vitality (p<0.001) in each case, while percentage morphologically abnormal sperm cells was significantly elevated (p<0.001) compared with the control values. There were significant decreases in the seminal and plasma ascorbic acid concentrations (p<0.001) in the males who had inadequate spermatogenesis compared with the control values. The plasma total cholesterol (TC) and body mass index (BMI) were not significantly different from the corresponding control values, but the plasma low density lipoprotein (LDLC) (p<0.001) and triglyceride (TG)(p<0.01) concentrations were significantly increased in all the patients. While the plasma high density lipoprotein cholesterol (HDLC)(p<0.001) was significantly decreased compared with the controls. The plasma lipid and lipoprotein levels did not demonstrate any definite pattern with the sperm characteristics. The decreased semen ascorbate level may play a significant role in the reduced sperm characteristics in these patients.

  15. Improving the Nightside Mid-latitude Ionospheric Density in the Global Ionosphere-Thermosphere Model

    NASA Astrophysics Data System (ADS)

    Wu, C.; Ridley, A. J.

    2017-12-01

    The ionosphere and plasmasphere interact with each other through upwelling of plasma into the plasmasphere during the day and downwelling of the plasma into the ionosphere during the night. The storage of ion density in the plasmasphere and subsequent downwelling maintains the ion density in the nighttime mid-latitude ionosphere. Global models of the upper atmosphere that do not contain a plasmasphere, but are limited in altitude, such as the Thermosphere Ionosphere Electrodynamics Global Circulation Model (TIEGCM) and the Global Ionosphere-Thermosphere Model(GITM) need a boundary condition that allows for some sort of downwelling to occur. In the TIEGCM, this has been set to a constant downward flux, while GITM has had no downwelling specification at all, which has caused the nighttime mid-latitude densities to be much too low. We present a new boundary condition in GITM, where there is downward ion flux from the upper boundary, allowing the ionosphere to be maintained during the night. This new boundary condition is dependent on the the Disturbance Storm Time (Dst), since, as the activity level increases (i.e., Dst decreases), the plasmasphere is eroded and will not serve to supply the ionosphere at night. Various quiet time and active time comparisons to ionosonde electron density and total electron content data will be presented that show that the ionospheric density in GITM is improved due to this new boundary condition.

  16. Effects of neutral distribution and external magnetic field on plasma momentum in electrodeless plasma thrusters

    NASA Astrophysics Data System (ADS)

    Takase, Kazuki; Takahashi, Kazunori; Takao, Yoshinori

    2018-02-01

    The effects of neutral distribution and an external magnetic field on plasma distribution and thruster performance are numerically investigated using a particle-in-cell simulation with Monte Carlo collisions (PIC-MCC) and the direct simulation Monte Carlo (DSMC) method. The modeled thruster consists of a quartz tube 1 cm in diameter and 3 cm in length, where a double-turn rf loop antenna is wound at the center of the tube and a solenoid is placed between the loop antenna and the downstream tube exit. A xenon propellant is introduced from both the upstream and downstream sides of the thruster, and the flow rates are varied while maintaining the total gas flow rate of 30 μg/s. The PIC-MCC calculations have been conducted using the neutral distribution obtained from the DSMC calculations, which were applied with different strengths of the magnetic field. The numerical results show that both the downstream gas injection and the external magnetic field with a maximum strength near the thruster exit lead to a shift of the plasma density peak from the upstream to the downstream side. Consequently, a larger total thrust is obtained when increasing the downstream gas injection and the magnetic field strength, which qualitatively agrees with a previous experiment using a helicon plasma source.

  17. Coupling of RF antennas to large volume helicon plasma

    NASA Astrophysics Data System (ADS)

    Chang, Lei; Hu, Xinyue; Gao, Lei; Chen, Wei; Wu, Xianming; Sun, Xinfeng; Hu, Ning; Huang, Chongxiang

    2018-04-01

    Large volume helicon plasma sources are of particular interest for large scale semiconductor processing, high power plasma propulsion and recently plasma-material interaction under fusion conditions. This work is devoted to studying the coupling of four typical RF antennas to helicon plasma with infinite length and diameter of 0.5 m, and exploring its frequency dependence in the range of 13.56-70 MHz for coupling optimization. It is found that loop antenna is more efficient than half helix, Boswell and Nagoya III antennas for power absorption; radially parabolic density profile overwhelms Gaussian density profile in terms of antenna coupling for low-density plasma, but the superiority reverses for high-density plasma. Increasing the driving frequency results in power absorption more near plasma edge, but the overall power absorption increases with frequency. Perpendicular stream plots of wave magnetic field, wave electric field and perturbed current are also presented. This work can serve as an important reference for the experimental design of large volume helicon plasma source with high RF power.

  18. Self-injection of electrons in a laser-wakefield accelerator by using longitudinal density ripple

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dahiya, Deepak; Sharma, A. K.; Sajal, Vivek

    By introducing a longitudinal density ripple (periodic modulation in background plasma density), we demonstrate self-injection of electrons in a laser-wakefield accelerator. The wakefield driven plasma wave, in presence of density ripple excites two side band waves of same frequency but different wave numbers. One of these side bands, having smaller phase velocity compared to wakefield driven plasma wave, preaccelerates the background plasma electrons. Significant number of these preaccelerated electrons get trapped in the laser-wakefield and further accelerated to higher energies.

  19. In-flight calibration of mesospheric rocket plasma probes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Havnes, Ove; University Studies Svalbard; Hartquist, Thomas W.

    Many effects and factors can influence the efficiency of a rocket plasma probe. These include payload charging, solar illumination, rocket payload orientation and rotation, and dust impact induced secondary charge production. As a consequence, considerable uncertainties can arise in the determination of the effective cross sections of plasma probes and measured electron and ion densities. We present a new method for calibrating mesospheric rocket plasma probes and obtaining reliable measurements of plasma densities. This method can be used if a payload also carries a probe for measuring the dust charge density. It is based on that a dust probe's effectivemore » cross section for measuring the charged component of dust normally is nearly equal to its geometric cross section, and it involves the comparison of variations in the dust charge density measured with the dust detector to the corresponding current variations measured with the electron and/or ion probes. In cases in which the dust charge density is significantly smaller than the electron density, the relation between plasma and dust charge density variations can be simplified and used to infer the effective cross sections of the plasma probes. We illustrate the utility of the method by analysing the data from a specific rocket flight of a payload containing both dust and electron probes.« less

  20. In-flight calibration of mesospheric rocket plasma probes.

    PubMed

    Havnes, Ove; Hartquist, Thomas W; Kassa, Meseret; Morfill, Gregor E

    2011-07-01

    Many effects and factors can influence the efficiency of a rocket plasma probe. These include payload charging, solar illumination, rocket payload orientation and rotation, and dust impact induced secondary charge production. As a consequence, considerable uncertainties can arise in the determination of the effective cross sections of plasma probes and measured electron and ion densities. We present a new method for calibrating mesospheric rocket plasma probes and obtaining reliable measurements of plasma densities. This method can be used if a payload also carries a probe for measuring the dust charge density. It is based on that a dust probe's effective cross section for measuring the charged component of dust normally is nearly equal to its geometric cross section, and it involves the comparison of variations in the dust charge density measured with the dust detector to the corresponding current variations measured with the electron and/or ion probes. In cases in which the dust charge density is significantly smaller than the electron density, the relation between plasma and dust charge density variations can be simplified and used to infer the effective cross sections of the plasma probes. We illustrate the utility of the method by analysing the data from a specific rocket flight of a payload containing both dust and electron probes.

  1. Effects of fiber density and plasma modification of nanofibrous membranes on the adhesion and growth of HaCaT keratinocytes.

    PubMed

    Bacakova, Marketa; Lopot, Frantisek; Hadraba, Daniel; Varga, Marian; Zaloudkova, Margit; Stranska, Denisa; Suchy, Tomas; Bacakova, Lucie

    2015-01-01

    It may be possible to regulate the cell colonization of biodegradable polymer nanofibrous membranes by plasma treatment and by the density of the fibers. To test this hypothesis, nanofibrous membranes of different fiber densities were treated by oxygen plasma with a range of plasma power and exposure times. Scanning electron microscopy and mechanical tests showed significant modification of nanofibers after plasma treatment. The intensity of the fiber modification increased with plasma power and exposure time. The exposure time seemed to have a stronger effect on modifying the fiber. The mechanical behavior of the membranes was influenced by the plasma treatment, the fiber density, and their dry or wet state. Plasma treatment increased the membrane stiffness; however, the membranes became more brittle. Wet membranes displayed significantly lower stiffness than dry membranes. X-ray photoelectron spectroscopy (XPS) analysis showed a slight increase in oxygen-containing groups on the membrane surface after plasma treatment. Plasma treatment enhanced the adhesion and growth of HaCaT keratinocytes on nanofibrous membranes. The cells adhered and grew preferentially on membranes of lower fiber densities, probably due to the larger area of void spaces between the fibers. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  2. Analysis of density effects in plasmas and their influence on electron-impact cross sections

    NASA Astrophysics Data System (ADS)

    Belkhiri, M.; Poirier, M.

    2014-12-01

    Density effects in plasmas are analyzed using a Thomas-Fermi approach for free electrons. First, scaling properties are determined for the free-electron potential and density. For hydrogen-like ions, the first two terms of an analytical expansion of this potential as a function of the plasma coupling parameter are obtained. In such ions, from these properties and numerical calculations, a simple analytical fit is proposed for the plasma potential, which holds for any electron density, temperature, and atomic number, at least assuming that Maxwell-Boltzmann statistics is applicable. This allows one to analyze perturbatively the influence of the plasma potential on energies, wave functions, transition rates, and electron-impact collision rates for single-electron ions. Second, plasmas with an arbitrary charge state are considered, using a modified version of the Flexible Atomic Code (FAC) package with a plasma potential based on a Thomas-Fermi approach. Various methods for the collision cross-section calculations are reviewed. The influence of plasma density on these cross sections is analyzed in detail. Moreover, it is demonstrated that, in a given transition, the radiative and collisional-excitation rates are differently affected by the plasma density. Some analytical expressions are proposed for hydrogen-like ions in the limit where the Born or Lotz approximation applies and are compared to the numerical results from the FAC.

  3. Measurements of Plasma Density in a Fast and Compact Plasma Focus Operating at Hundreds of Joules

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pavez, Cristian; Universidad de Concepcion, Facultad de Ciencias, Departamento de Fisica, Concepcion; Silva, Patricio

    2006-12-04

    It is known that there are plasma parameters that remain relatively constant for plasma focus facilities operating in a wide range of de energy, from 1kJ to 1MJ, such as: electron density, temperature and plasma energy density. Particularly the electron density is of the order of 1025m-3. Recently the experimental studies in plasma focus has been extended to devices operating under 1kJ, in the range of hundreds and tens of joules. In this work an optical refractive system was implemented in order to measure the electron density in a plasma focus devices of hundred of joules, PF-400J (880 nF, 30more » kV, 120 kA, 400 J, 300 ns time to peak current, dI/dt{approx}4x1011 A/s. The plasma discharge was synchronized with a pulsed Nd-YAG laser ({approx}6ns FWHM at 532nm) in order to obtain optical diagnostics as interferometry and Schlieren. An electron density of (0.9{+-}0.25)x1025m-3 was obtained at the axis of the plasma column close to the pinch time. This value is of the same order that the obtained in devices oparating in the energy range of 1kJ to 1MJ.« less

  4. One-dimensional particle-in-cell simulation on the influence of electron and ion temperature on the sheath expansion process in the post-arc stage of vacuum circuit breaker

    NASA Astrophysics Data System (ADS)

    Mo, Yongpeng; Shi, Zongqian; Jia, Shenli; Wang, Lijun

    2015-02-01

    The inter-contact region of vacuum circuit breakers is filled with residual plasma at the moment when the current is zero after the burning of metal vapor arc. The residual plasma forms an ion sheath in front of the post-arc cathode. The sheath then expands towards the post-arc anode under the influence of a transient recovery voltage. In this study, a one-dimensional particle-in-cell model is developed to investigate the post-arc sheath expansion. The influence of ion and electron temperatures on the decrease in local plasma density at the post-arc cathode side and post-arc anode side is discussed. When the decay in the local plasma density develops from the cathode and anode sides into the high-density region and merges, the overall plasma density in the inter-contact region begins to decrease. Meanwhile, the ion sheath begins to expand faster. Furthermore, the theory of ion rarefaction wave only explains quantitatively the decrease in the overall plasma density at relatively low ion temperatures. With the increase of ion temperature to certain extent, another possible reason for the decrease in the overall plasma density is proposed and results from the more active thermal diffusion of plasma.

  5. Plasma lipids, lipoproteins, and triglyceride turnover in eu- and hypo-thyroid rats and rats on a hypocaloric diet.

    PubMed

    Dory, L; Krause, B R; Roheim, P S

    1981-08-01

    Lipid and lipoprotein concentration, and triglyceride turnover were studied in control, thyroidectomized, and pair-fed control rats (pair-fed to match the food intake of the thyroidectomized rats). Thyroidectomy induced a significant increase in plasma cholesterol (and low density lipoprotein) concentrations and a decrease in plasma triglyceride (and very low density lipoprotein) concentrations. Changes in similar direction but of smaller magnitude were observed in the plasma of the pair-fed control rats. To further investigate triglyceride metabolism in these three groups of animals, triglyceride turnover was studied in fasted, unrestrained, and unanesthetized rats, following injection of [2-3H]glycerol. Peak incorporation of [2-3H]glycerol into plasma triglyceride occurred in all three groups of animals at 25 min after precursor administration, although the maximal incorporation was substantially lower in the thyroidectomized group than in either of the control groups. Thereafter, plasma triglyceride radioactivity decayed monoexponentially with a half-life of 24 +/- 1 min for both normal and pair-fed control rats, compared with the half-life of 41 +/- 3 min observed in the thyroidectomized rats. The calculated apparent fractional catabolic rates were thus 0.029 min-1 for both control groups and only 0.017 min-1 for the thyroidectomized animals. The apparent total catabolic rates of plasma triglyceride were 299 +/- 11, 138 +/- 11, and 48 +/- 4 micrograms triglyceride . min-1 for the normal controls, pair-fed controls, and thyroidectomized rats, respectively. These data further emphasize the importance of thyroid hormones in regulating plasma lipid and lipoprotein metabolism and, specifically, indicate that hypothyroidism results in a reduction of triglyceride secretion into, and the removal from, circulation. Furthermore, evidence was presented that the decreased caloric intake of the hypothyroid animals cannot, in itself, account for this observation.

  6. Plasma oscillations in spherical Gaussian shaped ultracold neutral plasma

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chen, Tianxing; Lu, Ronghua, E-mail: lurh@siom.ac.cn; Guo, Li

    2016-04-15

    The collective plasma oscillations are investigated in ultracold neutral plasma with a non-uniform density profile. Instead of the plane configuration widely used, we derive the plasma oscillation equations with spherically symmetric distribution and Gaussian density profile. The damping of radial oscillation is found. The Tonks–Dattner resonances of the ultracold neutral plasma with an applied RF field are also calculated.

  7. Plasma Properties of Microwave Produced Plasma in a Toroidal Device

    NASA Astrophysics Data System (ADS)

    Singh, Ajay; Edwards, W. F.; Held, Eric

    2011-10-01

    We have modified a small tokamak, STOR-1M, on loan from University of Saskatchewan, to operate as a low-temperature (~5 eV) toroidal plasma machine with externally induced toroidal magnetic fields ranging from zero to ~50 G. The plasma is produced using microwave discharges at relatively high pressures. Microwaves are produced by a kitchen microwave-oven magnetron operating at 2.45 GHz in continuous operating mode, resulting in pulses ~0.5 s in duration. Initial measurements of plasma formation in this device with and without applied magnetic fields are presented. Plasma density and temperature profiles have been measured using Langmuir probes and the magnetic field profile inside the plasma has been obtained using Hall probes. When the discharge is created with no applied toroidal magnetic field, the plasma does not fill the entire torus due to high background pressure. However, when a toroidal magnetic field is applied, the plasma flows along the applied field, filling the torus. Increasing the applied magnetic field seems to aid plasma formation - the peak density increases and the density gradient becomes steeper. Above a threshold magnetic field, the plasma develops low-frequency density oscillations due to probable excitation of flute modes in the plasma.

  8. Dielectronic recombination data for dynamic finite-density plasmas. XV. The silicon isoelectronic sequence

    NASA Astrophysics Data System (ADS)

    Kaur, Jagjit; Gorczyca, T. W.; Badnell, N. R.

    2018-02-01

    Context. We aim to present a comprehensive theoretical investigation of dielectronic recombination (DR) of the silicon-like isoelectronic sequence and provide DR and radiative recombination (RR) data that can be used within a generalized collisional-radiative modelling framework. Aims: Total and final-state level-resolved DR and RR rate coefficients for the ground and metastable initial levels of 16 ions between P+ and Zn16+ are determined. Methods: We carried out multi-configurational Breit-Pauli DR calculations for silicon-like ions in the independent processes, isolated resonance, distorted wave approximation. Both Δnc = 0 and Δnc = 1 core excitations are included using LS and intermediate coupling schemes. Results: Results are presented for a selected number of ions and compared to all other existing theoretical and experimental data. The total dielectronic and radiative recombination rate coefficients for the ground state are presented in tabulated form for easy implementation into spectral modelling codes. These data can also be accessed from the Atomic Data and Analysis Structure (ADAS) OPEN-ADAS database. This work is a part of an assembly of a dielectronic recombination database for the modelling of dynamic finite-density plasmas.

  9. Fully non-inductive plasma start-up with lower-hybrid waves using the outboard-launch and top-launch antennas on the TST-2 spherical tokamak

    NASA Astrophysics Data System (ADS)

    Tsujii, Naoto; Takase, Yuichi; Ejiri, Akira; Shinya, Takahiro; Yajima, Satoru; Yamazaki, Hibiki; Togashi, Hiro; Moeller, Charles P.; Roidl, Benedikt; Takahashi, Wataru; Toida, Kazuya; Yoshida, Yusuke

    2017-10-01

    Removal of the central solenoid is essential to realize an economical spherical tokamak fusion reactor, but non-inductive plasma start-up is a challenge. On the TST-2 spherical tokamak, non-inductive plasma start-up using lower-hybrid (LH) waves has been investigated. Using the capacitively-coupled combline (CCC) antenna installed at the outboard midplane, fully non-inductive plasma current ramp-up up to a quarter of that of the typical Ohmic discharges has been achieved. Although it was desirable to keep the density low during the plasma current ramp-up to avoid the LH density limit, it was recognized that there was a maximum current density that could be carried by a given electron density. Since the density needed to increase as the plasma current was ramped-up, the achievable plasma current was limited by the maximum operational toroidal field of TST-2. The top-launch CCC antenna was installed to access higher density with up-shift of the parallel index of refraction. Numerical analysis of LH current drive with the outboard-launch and top-launch antennas was performed and the results were qualitatively consistent with the experimental observations.

  10. Longitudinal gas-density profilometry for plasma-wakefield acceleration targets

    NASA Astrophysics Data System (ADS)

    Schaper, Lucas; Goldberg, Lars; Kleinwächter, Tobias; Schwinkendorf, Jan-Patrick; Osterhoff, Jens

    2014-03-01

    Precise tailoring of plasma-density profiles has been identified as one of the critical points in achieving stable and reproducible conditions in plasma wakefield accelerators. Here, the strict requirements of next generation plasma-wakefield concepts, such as hybrid-accelerators, with densities around 1017 cm-3 pose challenges to target fabrication as well as to their reliable diagnosis. To mitigate these issues we combine target simulation with fabrication and characterization. The resulting density profiles in capillaries with gas jet and multiple in- and outlets are simulated with the fluid code OpenFOAM. Satisfactory simulation results then are followed by fabrication of the desired target shapes with structures down to the 10 μm level. The detection of Raman scattered photons using lenses with large collection solid angle allows to measure the corresponding longitudinal density profiles at different number densities and allows a detection sensitivity down to the low 1017 cm-3 density range at high spatial resolution. This offers the possibility to gain insight into steep density gradients as for example in gas jets and at the plasma-to-vacuum transition.

  11. High-power, kilojoule laser interactions with near-critical density plasma

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Willingale, L.; Thomas, A. G. R.; Maksimchuk, A.

    Experiments were performed using the Omega EP laser, which provided pulses containing 1kJ of energy in 9ps and was used to investigate high-power, relativistic intensity laser interactions with near-critical density plasmas, created from foam targets with densities of 3-100 mg/cm{sup 3}. The effect of changing the plasma density on both the laser light transmitted through the targets and the proton beam accelerated from the interaction was investigated. Two-dimensional particle-in-cell simulations enabled the interaction dynamics and laser propagation to be studied in detail. The effect of the laser polarization and intensity in the two-dimensional simulations on the channel formation and electronmore » heating are discussed. In this regime, where the plasma density is above the critical density, but below the relativistic critical density, the channel formation speed and therefore length are inversely proportional to the plasma density, which is faster than the hole boring model prediction. A general model is developed to describe the channel length in this regime.« less

  12. The lipid-lowering effects of 4 weeks of daily soymilk or dairy milk ingestion in a postmenopausal female population.

    PubMed

    Beavers, Kristen M; Serra, Monica C; Beavers, Daniel P; Hudson, Geoffrey M; Willoughby, Darryn S

    2010-06-01

    Alterations in plasma cholesterol concentrations, especially increases in low-density lipoprotein (LDL), are well-known risk factors in the development of atherosclerosis. Numerous studies have examined the lipid-lowering effects of functional soy-containing foods, but few have specifically examined soymilk, with equivocal findings reported. In September 2008, a single-blind, randomized, controlled trial was conducted on 32 postmenopausal women at Baylor University, Waco, TX, USA. After a 2-week run-in period, subjects were randomly assigned to consume three servings of vanilla soy (n = 16) or reduced-fat dairy (n = 16) milk per day for 4 weeks. Plasma lipid profiles were obtained pre- and post-supplementation. Plasma high-density lipoprotein, LDL, and triglycerides were not significantly different between groups post-intervention (P = .45) or from baseline (P = .83). Separate analysis of plasma total cholesterol levels yielded similar results (P = .19 and P = .92, respectively). Furthermore, subanalyses controlling for dyslipidemia (n = 23) and lipid-lowering medication usage (n = 28) did not significantly alter results. Despite good dietary compliance, our study failed to show a significant hypocholesterolemic effect of soymilk consumption in this postmenopausal female population. Potential reasons for this nonsignificant finding are discussed, and future research directions are presented.

  13. Interhemispheric Propagation and Interactions of Auroral LSTIDs near the Equator

    NASA Astrophysics Data System (ADS)

    Pradipta, R.; Valladares, C.; Carter, B. A.; Doherty, P.

    2016-12-01

    In this work, we used experimental observations based on GPS total electron content (TEC) and ionosonde measurements to study some of the physics behind large-scale traveling ionospheric disturbances (LSTIDs) during the 26 September 2011 geomagnetic storm. In particular, we looked at how these LSTIDs propagate from the auroral zones all the way to the equatorial region and examined how the auroral LSTIDs from opposite hemispheres interact/interfere near the geomagnetic equator. We found that these LSTIDs had an overall propagation speed of ˜700 m/s. Furthermore, the resultant amplitude of the LSTID interference pattern was found to far exceed the sum of individual amplitudes of the incoming LSTIDs. We suspect that this peculiar intensification of auroral LSTIDs around the geomagnetic equator is facilitated by the significantly higher ceiling/canopy of the ionospheric plasma layer there. Normally, acoustic-gravity waves (AGWs) that leak upward (and thus increase in amplitude) would find a negligible level of plasma density at the topside ionosphere. However, the tip of the equatorial fountain at the geomagnetic equator constitutes a significant amount of plasma at a topside-equivalent altitude. The combination of increased AGW amplitudes and a higher plasma density at such altitude would therefore result in higher-amplitude LSTIDs in this particular region, as demonstrated in our observations and analysis.

  14. New detection system and signal processing for the tokamak ISTTOK heavy ion beam diagnostic.

    PubMed

    Henriques, R B; Nedzelskiy, I S; Malaquias, A; Fernandes, H

    2012-10-01

    The tokamak ISTTOK havy ion beam diagnostic (HIBD) operates with a multiple cell array detector (MCAD) that allows for the plasma density and the plasma density fluctuations measurements simultaneously at different sampling volumes across the plasma. To improve the capability of the plasma density fluctuations investigations, a new detection system and new signal conditioning amplifier have been designed and tested. The improvements in MCAD design are presented which allow for nearly complete suppression of the spurious plasma background signal by applying a biasing potential onto special electrodes incorporated into MCAD. The new low cost and small size transimpedance amplifiers are described with the parameters of 400 kHz, 10(7) V/A, 0.4 nA of RMS noise, adequate for the plasma density fluctuations measurements.

  15. Numerical study of the inductive plasma coupling to ramp up the plasma density for the Linac4 H- ion source

    NASA Astrophysics Data System (ADS)

    Ohta, M.; Mattei, S.; Yasumoto, M.; Hatayama, A.; Lettry, J.

    2014-02-01

    In the Linac4 H- ion source, the plasma is generated by an RF antenna operated at 2 MHz. In order to investigate the conditions necessary for ramping up the plasma density of the Linac4 H- ion source in the low plasma density, a numerical study has been performed for a wide range of parameter space of RF coil current and initial pressure from H2 gas injection. We have employed an Electromagnetic Particle in Cell model, in which the collision processes have been calculated by a Monte Carlo method. The results have shown that the range of initial gas pressure from 2 to 3 Pa is suitable for ramping up plasma density via inductive coupling.

  16. Long-term stability of the Io high-temperature plasma torus

    NASA Technical Reports Server (NTRS)

    Moos, H. W.; Skinner, T. E.; Durrance, S. T.; Feldman, P. D.; Festou, M. C.

    1985-01-01

    The short wavelength camera of the International Ultraviolet Explorer satellite was used to measure S II 1256, S III 1199, semiforbidden S III 1729, and semiforbidden S IV 1406 emission from the high-temperature region of the Io plasma torus. Observations over a period of five years (1979-1984) indicate that the Io plasma parameters have relatively small variations, particularly in the case of the mixing ratio for the dominant constituent S(++), and electron temperature. A simple three-dimensional model of the plasma torus was used to obtain the ion mixing ratios and the plasma density for each observation. The results are compared with Voyager 1 data for mixing ratio (ion density divided by electron density); ionization balance; and plasma density. The results of the comparison are discussed in detail.

  17. Injection of auxiliary electrons for increasing the plasma density in highly charged and high intensity ion sources

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Odorici, F., E-mail: fabrizio.odorici@bo.infn.it; Malferrari, L.; Montanari, A.

    Different electron guns based on cold- or hot-cathode technologies have been developed since 2009 at INFN for operating within ECR plasma chambers as sources of auxiliary electrons, with the aim of boosting the source performances by means of a higher plasma lifetime and density. Their application to microwave discharge ion sources, where plasma is not confined, has required an improvement of the gun design, in order to “screen” the cathode from the plasma particles. Experimental tests carried out on a plasma reactor show a boost of the plasma density, ranging from 10% to 90% when the electron guns are used,more » as explained by plasma diffusion models.« less

  18. Extreme plasma states in laser-governed vacuum breakdown.

    PubMed

    Efimenko, Evgeny S; Bashinov, Aleksei V; Bastrakov, Sergei I; Gonoskov, Arkady A; Muraviev, Alexander A; Meyerov, Iosif B; Kim, Arkady V; Sergeev, Alexander M

    2018-02-05

    Triggering vacuum breakdown at laser facility is expected to provide rapid electron-positron pair production for studies in laboratory astrophysics and fundamental physics. However, the density of the produced plasma may cease to increase at a relativistic critical density, when the plasma becomes opaque. Here, we identify the opportunity of breaking this limit using optimal beam configuration of petawatt-class lasers. Tightly focused laser fields allow generating plasma in a small focal volume much less than λ 3 and creating extreme plasma states in terms of density and produced currents. These states can be regarded to be a new object of nonlinear plasma physics. Using 3D QED-PIC simulations we demonstrate a possibility of reaching densities over 10 25  cm -3 , which is an order of magnitude higher than expected earlier. Controlling the process via initial target parameters provides an opportunity to reach the discovered plasma states at the upcoming laser facilities.

  19. Probing a dusty magnetized plasma with self-excited dust-density waves

    NASA Astrophysics Data System (ADS)

    Tadsen, Benjamin; Greiner, Franko; Piel, Alexander

    2018-03-01

    A cloud of nanodust particles is created in a reactive argon-acetylene plasma. It is then transformed into a dusty magnetized argon plasma. Plasma parameters are obtained with the dust-density wave diagnostic introduced by Tadsen et al. [Phys. Plasmas 22, 113701 (2015), 10.1063/1.4934927]. A change from an open to a cylindrically enclosed nanodust cloud, which was observed earlier, can now be explained by a stronger electric confinement if a vertical magnetic field is present. Using two-dimensional extinction measurements and the inverse Abel transform to determine the dust density, a redistribution of the dust with increasing magnetic induction is found. The dust-density profile changes from being peaked around the central void to being peaked at an outer torus ring resulting in a hollow profile. As the plasma parameters cannot explain this behavior, we propose a rotation of the nanodust cloud in the magnetized plasma as the origin of the modified profile.

  20. Device and method for electron beam heating of a high density plasma

    DOEpatents

    Thode, Lester E.

    1981-01-01

    A device and method for relativistic electron beam heating of a high density plasma in a small localized region. A relativistic electron beam generator produces a high voltage electron beam which propagates along a vacuum drift tube and is modulated to initiate electron bunching within the beam. The beam is then directed through a low density gas chamber which provides isolation between the vacuum modulator and the relativistic electron beam target. The relativistic beam is then applied to a high density target plasma which typically comprises DT, DD, hydrogen boron or similar thermonuclear gas at a density of 10.sup.17 to 10.sup.20 electrons per cubic centimeter. The target plasma is ionized prior to application of the electron beam by means of a laser or other preionization source. Utilizing a relativistic electron beam with an individual particle energy exceeding 3 MeV, classical scattering by relativistic electrons passing through isolation foils is negligible. As a result, relativistic streaming instabilities are initiated within the high density target plasma causing the relativistic electron beam to efficiently deposit its energy into a small localized region within the high density plasma target.

  1. Human absorption of a supplement containing purified hydroxytyrosol, a natural antioxidant from olive oil, and evidence for its transient association with low-density lipoproteins.

    PubMed

    González-Santiago, Maria; Fonollá, Juristo; Lopez-Huertas, Eduardo

    2010-04-01

    There is growing interest in the health effects of olive oil polyphenols, particularly hydroxytyrosol (HT), for their potential application in the treatment of inflammatory conditions such as cardiovascular disease (CVD). As oxidative modification of low-density lipoproteins (LDL) plays a central role in the development of CVD, natural antioxidants are a main target for the nutraceutical industry. In this study we firstly investigated the absorption of pure hydroxytyrosol (99.5%) administered as a supplement in an aqueous solution (2.5mg/kg BW) in the plasma and urine of healthy volunteers (n=10). Plasma C(max) for HT and homovanillic alcohol (HvOH) were detected at 13.0+/-1.5 and 16.7+/-2.4min, respectively. The HT and HvOH levels were undetectable 2-h after the administration. HT, HvOH, homovanillic acid and 3,4-dihydroxyphenylacetic acid were found as free forms (44%) or as glucuronide (34.4%) or sulphate (21.2%) conjugates in the 24-h urine samples of the subjects. In a second phase of the study, the same amounts of HT were administered to the subjects and the presence of HT in purified plasma lipoproteins was investigated in LDL fractions freshly isolated. 10min after the ingestion of the HT supplement, more than 50% of the total amount detected was present in the LDL-purified fractions and its concentration declined in accordance with its presence in plasma but no changes were found in total antioxidant capacity, malondialdehyde or LDL lag time. These results indicate that pure HT transiently associates with LDL lipoproteins in vivo. Copyright 2009 Elsevier Ltd. All rights reserved.

  2. Effects of rose hip intake on risk markers of type 2 diabetes and cardiovascular disease: a randomized, double-blind, cross-over investigation in obese persons

    PubMed Central

    Andersson, U; Berger, K; Högberg, A; Landin-Olsson, M; Holm, C

    2012-01-01

    BACKGROUND/OBJECTIVES: In studies performed in mice, rose hip powder has been shown to both prevent and reverse high-fat diet-induced obesity and glucose intolerance as well as reduce plasma levels of cholesterol. The aim of this study was to investigate whether daily intake of rose hip powder over 6 weeks exerts beneficial metabolic effects in obese individuals. SUBJECTS/METHODS: A total of 31 obese individuals with normal or impaired glucose tolerance were enrolled in a randomized, double-blind, cross-over study in which metabolic effects of daily intake of a rose hip powder drink over 6 weeks was compared with a control drink. Body weight, glucose tolerance, blood pressure, blood lipids and markers of inflammation were assessed in the subjects. RESULTS: In comparison with the control drink, 6 weeks of daily consumption of the rose hip drink resulted in a significant reduction of systolic blood pressure (−3.4% P=0.021), total plasma cholesterol (−4.9% P=0.0018), low-density lipoprotein (LDL) cholesterol (−6.0% P=0.012) and LDL/HDL ratio (−6.5% P=0.041). The Reynolds risk assessment score for cardiovascular disease was decreased in the rose hip group compared with the control group (−17% P=0.007). Body weight, diastolic blood pressure, glucose tolerance, and plasma levels of high-density lipoprotein (HDL) cholesterol, triglycerides, incretins and markers of inflammation did not differ between the two groups. CONCLUSIONS: Daily consumption of 40 g of rose hip powder for 6 weeks can significantly reduce cardiovascular risk in obese people through lowering of systolic blood pressure and plasma cholesterol levels. PMID:22166897

  3. Shack-Hartmann Electron Densitometer (SHED): An Optical System for Diagnosing Free Electron Density in Laser-Produced Plasmas

    DTIC Science & Technology

    2016-11-01

    a few nanoseconds. The challenge remains to diagnose plasmas via the free electron density in this short window of time and often in a small volume ...Free Electron Density in Laser-Produced Plasmas by Anthony R Valenzuela Approved for public release; distribution is...US Army Research Laboratory Shack-Hartmann Electron Densitometer (SHED): An Optical System for Diagnosing Free Electron Density in Laser

  4. Surface currents associated with external kink modes in tokamak plasmas during a major disruption

    NASA Astrophysics Data System (ADS)

    Ng, C. S.; Bhattacharjee, A.

    2017-10-01

    The surface current on the plasma-vacuum interface during a disruption event involving kink instability can play an important role in driving current into the vacuum vessel. However, there have been disagreements over the nature or even the sign of the surface current in recent theoretical calculations based on idealized step-function background plasma profiles. We revisit such calculations by replacing step-function profiles with more realistic profiles characterized by a strong but finite gradient along the radial direction. It is shown that the resulting surface current is no longer a delta-function current density, but a finite and smooth current density profile with an internal structure, concentrated within the region with a strong plasma pressure gradient. Moreover, this current density profile has peaks of both signs, unlike the delta-function case with a sign opposite to, or the same as the plasma current. We show analytically and numerically that such current density can be separated into two parts, with one of them, called the convective current density, describing the transport of the background plasma density by the displacement, and the other part that remains, called the residual current density. It is argued that consideration of both types of current density is important and can resolve past controversies.

  5. Device and method for imploding a microsphere with a fast liner

    DOEpatents

    Thode, Lester E.

    1981-01-01

    A device and method for relativistic electron beam heating of a high-density plasma in a small localized region. A relativistic electron beam generator or accelerator produces a high-voltage electron beam which propagates along a vacuum drift tube and is modulated to initiate electron bunching within the beam. The beam is then directed through a low-density gas chamber which provides isolation between the vacuum modulator and the relativistic electron beam target. The relativistic beam is then applied to a high-density target plasma which typically comprises DT, DD, hydrogen boron or similar thermonuclear gas at a density of 10.sup.17 to 10.sup.20 electrons per cubic centimeter. The target gas is ionized prior to application of the electron beam by means of a laser or other preionization source to form a plasma. Utilizing a relativistic electron beam with an individual particle energy exceeding 3 MeV, classical scattering by relativistic electrons passing through isolation foils is negligible. As a result, relativistic streaming instabilities are initiated within the high-density target plasma causing the relativistic electron beam to efficiently deposit its energy and momentum into a small localized region of the high-density plasma target. Fast liners disposed in the high-density target plasma are explosively or ablatively driven to implosion by a heated annular plasma surrounding the fast liner generated by an annular relativistic electron beam. An azimuthal magnetic field produced by axial current flow in the annular plasma, causes the energy in the heated annular plasma to converge on the fast liner to drive the fast liner to implode a microsphere.

  6. Battery-Powered RF Pre-Ionization System for the Caltech Magnetohydrodynamically-Driven Jet Experiment: RF Discharge Properties and MHD-Driven Jet Dynamics

    NASA Astrophysics Data System (ADS)

    Chaplin, Vernon H.

    This thesis describes investigations of two classes of laboratory plasmas with rather different properties: partially ionized low pressure radiofrequency (RF) discharges, and fully ionized high density magnetohydrodynamically (MHD)-driven jets. An RF pre-ionization system was developed to enable neutral gas breakdown at lower pressures and create hotter, faster jets in the Caltech MHD-Driven Jet Experiment. The RF plasma source used a custom pulsed 3 kW 13.56 MHz RF power amplifier that was powered by AA batteries, allowing it to safely float at 4-6 kV with the cathode of the jet experiment. The argon RF discharge equilibrium and transport properties were analyzed, and novel jet dynamics were observed. Although the RF plasma source was conceived as a wave-heated helicon source, scaling measurements and numerical modeling showed that inductive coupling was the dominant energy input mechanism. A one-dimensional time-dependent fluid model was developed to quantitatively explain the expansion of the pre-ionized plasma into the jet experiment chamber. The plasma transitioned from an ionizing phase with depressed neutral emission to a recombining phase with enhanced emission during the course of the experiment, causing fast camera images to be a poor indicator of the density distribution. Under certain conditions, the total visible and infrared brightness and the downstream ion density both increased after the RF power was turned off. The time-dependent emission patterns were used for an indirect measurement of the neutral gas pressure. The low-mass jets formed with the aid of the pre-ionization system were extremely narrow and collimated near the electrodes, with peak density exceeding that of jets created without pre-ionization. The initial neutral gas distribution prior to plasma breakdown was found to be critical in determining the ultimate jet structure. The visible radius of the dense central jet column was several times narrower than the axial current channel radius, suggesting that the outer portion of the jet must have been force free, with the current parallel to the magnetic field. The studies of non-equilibrium flows and plasma self-organization being carried out at Caltech are relevant to astrophysical jets and fusion energy research.

  7. Plasma density characterization at SPARC_LAB through Stark broadening of Hydrogen spectral lines

    NASA Astrophysics Data System (ADS)

    Filippi, F.; Anania, M. P.; Bellaveglia, M.; Biagioni, A.; Chiadroni, E.; Cianchi, A.; Di Giovenale, D.; Di Pirro, G.; Ferrario, M.; Mostacci, A.; Palumbo, L.; Pompili, R.; Shpakov, V.; Vaccarezza, C.; Villa, F.; Zigler, A.

    2016-09-01

    Plasma-based acceleration techniques are of great interest for future, compact accelerators due to their high accelerating gradient. Both particle-driven and laser-driven Plasma Wakefield Acceleration experiments are foreseen at the SPARC_LAB Test Facility (INFN National Laboratories of Frascati, Italy), with the aim to accelerate high-brightness electron beams. In order to optimize the efficiency of the acceleration in the plasma and preserve the quality of the accelerated beam, the knowledge of the plasma electron density is mandatory. The Stark broadening of the Hydrogen spectral lines is one of the candidates used to characterize plasma density. The implementation of this diagnostic for plasma-based experiments at SPARC_LAB is presented.

  8. Entropy Generation Across Earth's Bow Shock

    NASA Technical Reports Server (NTRS)

    Parks, George K.; McCarthy, Michael; Fu, Suiyan; Lee E. s; Cao, Jinbin; Goldstein, Melvyn L.; Canu, Patrick; Dandouras, Iannis S.; Reme, Henri; Fazakerley, Andrew; hide

    2011-01-01

    Earth's bow shock is a transition layer that causes an irreversible change in the state of plasma that is stationary in time. Theories predict entropy increases across the bow shock but entropy has never been directly measured. Cluster and Double Star plasma experiments measure 3D plasma distributions upstream and downstream of the bow shock that allow calculation of Boltzmann's entropy function H and his famous H-theorem, dH/dt O. We present the first direct measurements of entropy density changes across Earth's bow shock. We will show that this entropy generation may be part of the processes that produce the non-thermal plasma distributions is consistent with a kinetic entropy flux model derived from the collisionless Boltzmann equation, giving strong support that solar wind's total entropy across the bow shock remains unchanged. As far as we know, our results are not explained by any existing shock models and should be of interests to theorists.

  9. Effect of exponential density transition on self-focusing of q-Gaussian laser beam in collisionless plasma

    NASA Astrophysics Data System (ADS)

    Valkunde, Amol T.; Vhanmore, Bandopant D.; Urunkar, Trupti U.; Gavade, Kusum M.; Patil, Sandip D.; Takale, Mansing V.

    2018-05-01

    In this work, nonlinear aspects of a high intensity q-Gaussian laser beam propagating in collisionless plasma having upward density ramp of exponential profiles is studied. We have employed the nonlinearity in dielectric function of plasma by considering ponderomotive nonlinearity. The differential equation governing the dimensionless beam width parameter is achieved by using Wentzel-Kramers-Brillouin (WKB) and paraxial approximations and solved it numerically by using Runge-Kutta fourth order method. Effect of exponential density ramp profile on self-focusing of q-Gaussian laser beam for various values of q is systematically carried out and compared with results Gaussian laser beam propagating in collisionless plasma having uniform density. It is found that exponential plasma density ramp causes the laser beam to become more focused and gives reasonably interesting results.

  10. Measurements of neutral helium density in helicon plasmas.

    PubMed

    Houshmandyar, Saeid; Sears, Stephanie H; Thakur, Saikat Chakraborty; Carr, Jerry; Galante, Matthew E; Scime, Earl E

    2010-10-01

    Laser-induced-fluorescence (LIF) is used to measure the density of helium atoms in a helicon plasma source. For a pump wavelength of 587.725 nm (vacuum) and laser injection along the magnetic field, the LIF signal exhibits a signal decrease at the Doppler shifted central wavelength. The drop in signal results from the finite optical depth of the plasma and the magnitude of the decrease is proportional to the density of excited state neutral atoms. Using Langmuir probe measurements of plasma density and electron temperature and a collisional-radiative model, the absolute ground state neutral density is calculated from the optical depth measurements. Optimal plasma performance, i.e., the largest neutral depletion on the axis of the system, is observed for antenna frequencies of 13.0 and 13.5 MHz and magnetic field strengths of 550-600 G.

  11. Ionospheric TEC Weather Map Over South America

    NASA Astrophysics Data System (ADS)

    Takahashi, H.; Wrasse, C. M.; Denardini, C. M.; Pádua, M. B.; de Paula, E. R.; Costa, S. M. A.; Otsuka, Y.; Shiokawa, K.; Monico, J. F. Galera; Ivo, A.; Sant'Anna, N.

    2016-11-01

    Ionospheric weather maps using the total electron content (TEC) monitored by ground-based Global Navigation Satellite Systems (GNSS) receivers over South American continent, TECMAP, have been operationally produced by Instituto Nacional de Pesquisas Espaciais's Space Weather Study and Monitoring Program (Estudo e Monitoramento Brasileiro de Clima Especial) since 2013. In order to cover the whole continent, four GNSS receiver networks, (Rede Brasileiro de Monitoramento Contínuo) RBMC/Brazilian Institute for Geography and Statistics, Low-latitude Ionospheric Sensor Network, International GNSS Service, and Red Argentina de Monitoreo Satelital Continuo, in total 140 sites, have been used. TECMAPs with a time resolution of 10 min are produced in 12 h time delay. Spatial resolution of the map is rather low, varying between 50 and 500 km depending on the density of the observation points. Large day-to-day variabilities of the equatorial ionization anomaly have been observed. Spatial gradient of TEC from the anomaly trough (total electron content unit, 1 TECU = 1016 el m-2 (TECU) <10) to the crest region (TECU > 80) causes a large ionospheric range delay in the GNSS positioning system. Ionospheric plasma bubbles, their seeding and development, could be monitored. This plasma density (spatial and temporal) variability causes not only the GNSS-based positioning error but also radio wave scintillations. Monitoring of these phenomena by TEC mapping becomes an important issue for space weather concern for high-technology positioning system and telecommunication.

  12. Chromatographic analysis of lipid fractions in healthy dogs and dogs with obesity or hyperadrenocorticism.

    PubMed

    Jericó, Márcia Marques; De Camargo Chiquito, Fernanda; Kajihara, Kazuo; Moreira, Márcio Antonio Bastistela; Gonzales, Rodrigo; Machado, Fabricio Lorenzini Aranha; Nunes, Valéria Sutti; Catanozi, Sergio; Nakandakare, Edna Regina

    2009-03-01

    Obesity and endogenous hyperadrenocorticism (HAC) are common clinical conditions in veterinary practice, and both conditions have clinical and laboratory similarities, such as weight gain and dyslipidemia. The objective of the present study was to characterize and compare the lipid profiles and plasma lipoprotein fractions in healthy dogs (n = 10), in obese dogs (n = 10), and in dogs with HAC (n = 6). All of the dogs were client owned. The lipoproteins were separated by fast protein liquid chromatography, and the plasma concentrations of total cholesterol and total triacylglycerol (TAG) were determined by enzymatic methods. When compared with the healthy and obese groups, dogs with HAC had a significant increase (P < 0.01) in the total concentrations of TAGs and cholesterol (CHOL), with higher distribution in the very low-density lipoprotein (VLDL)-CHOL fractions. In addition, the distributions of the high-density lipoprotein (HDL)-CHOL and HDL-TAG fractions were significantly lower (P < 0.01) in dogs with HAC than in healthy dogs. Considering the animals in this study, it was determined that the dogs with HAC differed significantly from the healthy and obese dogs regarding the metabolism of CHOL and TAG, as well as their VLDL and HDL fractions. Similar laboratory findings could allow veterinarians to distinguish obese dogs from those with HAC. In addition, dogs with HAC may be at higher risk for developing metabolic and atherosclerotic complications.

  13. Hepatoprotective effect of Arctium lappa root extract on cadmium toxicity in adult Wistar rats.

    PubMed

    de Souza Predes, Fabricia; da Silva Diamante, Maria Aparecida; Foglio, Mary Ann; Camargo, Camila de Andrade; Camargo, Camila Almeida; Aoyama, Hiroshi; Miranda, Silvio Cesar; Cruz, Bread; Gomes Marcondes, Maria Cristina Cintra; Dolder, Heidi

    2014-08-01

    This study was performed to determine the effects of Arctium lappa (Al) to protect against cadmium damage in the rat liver. Male rats received a single i.p. dose of CdCl2 (1.2 mg/kg body weight (BW)) with or without Al extract administered daily by gavage (300 mg/kg BW) for 7 or 56 days. After 7 days, Al caused plasma transaminase activity to diminish in groups Al (glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT)) and CdAl (GPT). After 56 days, GOT and GPT plasma activities were reduced in the Cd group. No alteration in plasma levels of creatinine, total bilirubin, and total protein were observed. GOT liver activity increased in the Cd group. No alteration was observed in superoxide dismutase (SOD), catalase (CAT), glutathione-S-transferase (GST), and malondialdehyde (MDA) dosage. In the Cd group, hepatocyte proportion decreased and sinusoid capillary proportion increased. In the Al and CdAl groups, the nuclear proportion increased and the cytoplasmic proportion decreased. The hepatocyte nucleus density reduced in Cd and increased in the Al group. After 56 days, there was no alteration in the Cd group. In Al and CdAl groups, the nuclear proportion increased without cytoplasmic proportion variation, but the sinusoid capillary proportion was reduced. The hepatocyte nucleus density decreased in the Cd group and increased in the Al and CdAl groups. In conclusion, the liver function indicators showed that A. lappa protected the liver against cadmium toxicity damage.

  14. Spectral effects in the propagation of chirped laser pulses in uniform underdense plasma

    NASA Astrophysics Data System (ADS)

    Pathak, Naveen; Zhidkov, Alexei; Hosokai, Tomonao; Kodama, Ryosuke

    2018-01-01

    Propagation of linearly chirped and linearly polarized, powerful laser pulses in uniform underdense plasma with their duration exceeding the plasma wave wavelength is examined via 3D fully relativistic particle-in-cell simulations. Spectral evolution of chirped laser pulses, determined by Raman scattering, essentially depends on the nonlinear electron evacuation from the first wake bucket via modulation of the known parameter /n e ( r ) ω0 2 γ . Conversely, the relative motion of different spectral components inside a pulse changes the evolution of the pulse length and, therefore, the ponderomotive forces at the pulse rear. Such longitudinal dynamics of the pulse length provoke a parametric resonance in the laser wake with continuous electron self-injection for any chirped pulses. However, the total charge of accelerated electrons and their energy distribution essentially depends on the chirp. Besides, negatively chirped laser pulses are shown to be useful for spatially resolved measurements of the plasma density profiles and for rough estimations of the laser pulse intensity evolution in underdense plasma.

  15. Fine Structure of a Laser-Plasma Filament in Air

    NASA Astrophysics Data System (ADS)

    Eisenmann, Shmuel; Pukhov, Anatoly; Zigler, Arie

    2007-04-01

    The ability to select and stabilize a single filament during propagation of an ultrashort high-intensity laser pulse in air makes it possible to examine the longitudinal structure of the plasma channel left in its wake. We present detailed measurements of plasma density variations along laser propagation. Over the length of the filament, electron density variations of 3 orders of magnitude are measured. They display evidence of a meter-long postionization range, along which a self-guided structure is observed coupled with a low plasma density, corresponding to ˜3 orders of magnitude decrease from the peak density level.

  16. Atomic oxygen behavior at downstream of AC excited atmospheric pressure He plasma jet

    NASA Astrophysics Data System (ADS)

    Takeda, Keigo; Ishikawa, Kenji; Tanaka, Hiromasa; Sekine, Makoto; Hori, Masaru

    2016-09-01

    Applications of atmospheric pressure plasma jets (APPJ) have been investigated in the plasma medical fields such as cancer therapy, blood coagulation, etc. Reactive species generated by the plasma jet interacts with the biological surface. Therefore, the issue attracts much attentions to investigate the plasma effects on targets. In our group, a spot-size AC excited He APPJ have been used for the plasma medicine. From diagnostics of the APPJ using optical emission spectroscopy, the gas temperature and the electron density was estimated to be 299 K and 3.4 ×1015 cm-3. The AC excited He APPJ which affords high density plasma at room temperature is considered to be a powerful tool for the medical applications. In this study, by using vacuum ultraviolet absorption spectroscopy, the density of atomic oxygen on a floating copper as a target irradiated by the He APPJ was measured as a function of the distance between the plasma source and the copper wire. The measured density became a maximum value around 8 ×1013 cm-3 at 12 mm distance, and then decreased over the distance. It is considered that the behavior was due to the changes in the plasma density on the copper wire and influence of ambient air.

  17. Radiative transition of hydrogen-like ions in quantum plasma

    NASA Astrophysics Data System (ADS)

    Hu, Hongwei; Chen, Zhanbin; Chen, Wencong

    2016-12-01

    At fusion plasma electron temperature and number density regimes of 1 × 103-1 × 107 K and 1 × 1028-1 × 1031/m3, respectively, the excited states and radiative transition of hydrogen-like ions in fusion plasmas are studied. The results show that quantum plasma model is more suitable to describe the fusion plasma than the Debye screening model. Relativistic correction to bound-state energies of the low-Z hydrogen-like ions is so small that it can be ignored. The transition probability decreases with plasma density, but the transition probabilities have the same order of magnitude in the same number density regime.

  18. Wire array Z-pinch insights for enhanced x-ray production

    NASA Astrophysics Data System (ADS)

    Sanford, T. W. L.; Mock, R. C.; Spielman, R. B.; Haines, M. G.; Chittenden, J. P.; Whitney, K. G.; Apruzese, J. P.; Peterson, D. L.; Greenly, J. B.; Sinars, D. B.; Reisman, D. B.; Mosher, D.

    1999-05-01

    Comparisons of measured total radiated x-ray power from annular wire-array z-pinches with a variety of models as a function of wire number, array mass, and load radius are reviewed. The data, which are comprehensive, have provided important insights into the features of wire-array dynamics that are critical for high x-ray power generation. Collectively, the comparisons of the data with the model calculations suggest that a number of underlying dynamical mechanisms involving cylindrical asymmetries and plasma instabilities contribute to the measured characteristics. For example, under the general assumption that the measured risetime of the total-radiated-power pulse is related to the thickness of the plasma shell formed on axis, the Heuristic Model [IEEE Trans. Plasma Sci. 26, 1275 (1998)] agrees with the measured risetime under a number of specific assumptions about the way the breakdown of the wires, the wire-plasma expansion, and the Rayleigh-Taylor instability in the r-z plane, develop. Likewise, in the high wire-number regime (where the wires are calculated to form a plasma shell prior to significant radial motion of the shell) the comparisons show that the variation in the power of the radiation generated as a function of load mass and array radius can be simulated by the two-dimensional Eulerian-radiation- magnetohydrodynamics code (E-RMHC) [Phys. Plasmas 3, 368 (1996)], using a single random-density perturbation that seeds the Rayleigh-Taylor instability in the r-z plane. For a given pulse-power generator, the comparisons suggest that (1) the smallest interwire gaps compatible with practical load construction and (2) the minimum implosion time consistent with the optimum required energy coupling of the generator to the load should produce the highest total-radiated-power levels.

  19. Effect of Piper betle on plasma antioxidant status and lipid profile against D-galactosamine-induced hepatitis in rats.

    PubMed

    Pushpavalli, Ganesan; Veeramani, Chinnadurai; Pugalendi, Kodukkur Viswanathan

    2009-01-01

    Betle leaf chewing is an old traditional practice in India and other countries of East Asia. We have investigated the antioxidant and antihyperlipidaemic potential of an alcoholic leaf-extract of Piper betle against D-galactosamine (D-GalN; 400 mg/kg body weight, i.p. single dose) intoxication in male albino Wistar rats. Rats were treated with leaf-extract (200 mg/kg body weight) by intragastric intubations daily for 20 days. The animals were divided randomly into five groups of six animals each as control, control plus extract, D-GalN control, D-GalN-rats on treatment with extract or silymarin, a standard drug. We observed an increase in the plasma levels of thiobarbituric acid reactive substances (TBARS), lipid hydroperoxides, and a decrease in vitamin C, vitamin E and reduced glutathione concentrations. Very low density lipoprotein cholesterol and low density lipoprotein cholesterol increased significantly while high density lipoprotein cholesterol decreased. Further, increase in the levels of total cholesterol, phospholipids, triglycerides, free fatty acids in the plasma and tissues of liver and kidney were observed in D-GalN-treated rats. Administration of P. betle leaf-extract prevented the increase or decrease of these parameters and brought towards normality. These results suggest that P. betle could afford a significant antioxidant and antihyperlipidaemic effect against D-GalN-intoxication.

  20. Estimations of Kappa parameter using quasi-thermal noise spectroscopy: Applications on Wind spacecraft

    NASA Astrophysics Data System (ADS)

    Martinović, M.

    2017-12-01

    Quasi-thermal noise (QTN) spectroscopy is an accurate technique for in situ measurements of electron density and temperature in space plasmas. The QTN spectrum has a characteristic noise peak just above the plasma frequency produced by electron quasi-thermal fluctuations, which allows a very accurate measurement of the electron density. The size and shape of the peak are determined by suprathermal electrons. Since this nonthermal electron population is well described by a generalized Lorentzian - Kappa velocity distribution, it is possible to determinate the distribution properties in the solar wind from a measured spectrum. In this work, we discuss some basic properties of the QTN spectrum dependence of the Kappa distribution parameters - total electron density, temperature and the Kappa index, giving an overview on how instrument characteristics and environment conditions affect quality of the measurements. Further on, we aim to apply the method to Wind Thermal Noise Receiver (TNR) measurements. However, the spectra observed by this instrument usually contain contributions from nonthermal phenomena, like ion acoustic waves below, or galactic noise above the plasma frequency. This is why, besides comparison of the theory with observations, work with Wind data requires development of a sophisticated algorithm that distinguish parts of the spectra that are dominated by the QTN, and therefore can be used in our study. Postulates of this algorithm, as well as major results of its implementation, are also presented.

  1. Plasma Disks and Rings with ``High'' Magnetic Energy Densities

    NASA Astrophysics Data System (ADS)

    Coppi, B.; Rousseau, F.

    2006-04-01

    The nonlinear theory of rotating axisymmetric thin structures in which the magnetic field energy density is comparable with the thermal plasma energy density is formulated. The only flow velocity included in the theory is the velocity of rotation around a central object whose gravity is dominant. The periodic sequence, in the radial direction, of pairs of opposite current channels that can form is shown to lead to relatively large plasma density and pressure modulations, while the relevant magnetic surfaces can acquire a ``crystal structure.'' A new class of equilibria consisting of a series of plasma rings is identified, in the regimes where the plasma pressure is comparable to the magnetic pressure associated with the fields produced by the internal currents. The possible relevance of this result to the formation of dusty plasma rings is pointed out.

  2. Kinetic simulations of the stability of a plasma confined by the magnetic field of a current rod

    NASA Astrophysics Data System (ADS)

    Tonge, J.; Leboeuf, J. N.; Huang, C.; Dawson, J. M.

    2003-09-01

    The kinetic stability of a plasma in the magnetic field of a current rod is investigated for various temperature and density profiles using three-dimensional particle-in-cell simulations. Such a plasma obeys similar physics to a plasma in a dipole magnetic field, while it is easier to perform computer simulations, and do theoretical analysis, of a plasma in the field of a current rod. Simple energy principle calculations and simulations with a variety of temperature and density profiles show that the plasma is stable to interchange for pressure profiles proportional to r-10/3. As predicted by theory the simulations also show that the density profile will be stationary as long as density is proportional to r-2 even though the temperature profile may not be stable.

  3. THEMIS two‐point measurements of the cross‐tail current density: A thick bifurcated current sheet in the near‐Earth plasma sheet

    PubMed Central

    2015-01-01

    Abstract The basic properties of the near‐Earth current sheet from 8 RE to 12 RE were determined based on Time History of Events and Macroscale Interactions during Substorms (THEMIS) observations from 2007 to 2013. Ampere's law was used to estimate the current density when the locations of two spacecraft were suitable for the calculation. A total of 3838 current density observations were obtained to study the vertical profile. For typical solar wind conditions, the current density near (off) the central plane of the current sheet ranged from 1 to 2 nA/m2 (1 to 8 nA/m2). All the high current densities appeared off the central plane of the current sheet, indicating the formation of a bifurcated current sheet structure when the current density increased above 2 nA/m2. The median profile also showed a bifurcated structure, in which the half thickness was about 3 RE. The distance between the peak of the current density and the central plane of the current sheet was 0.5 to 1 RE. High current densities above 4 nA/m2 were observed in some cases that occurred preferentially during substorms, but they also occurred in quiet times. In contrast to the commonly accepted picture, these high current densities can form without a high solar wind dynamic pressure. In addition, these high current densities can appear in two magnetic configurations: tail‐like and dipolar structures. At least two mechanisms, magnetic flux depletion and new current system formation during the expansion phase, other than plasma sheet compression are responsible for the formation of the bifurcated current sheets. PMID:27722039

  4. EFFECTS OF LASER RADIATION ON MATTER. LASER PLASMA: Steepening of the density profile under the action of a ponderomotive force during isothermal planar plasma expansion

    NASA Astrophysics Data System (ADS)

    Garanin, Sergey G.; Kir'yanov, Yu F.; Kochemasov, G. G.

    1990-06-01

    A theoretical investigation is reported of the deformation of the density profile of a plasma by a ponderomotive force under transient conditions. Initially, the structure of the density profile near the critical point coincides exactly with the solution of the steady-state problem. Plasma expansion is accompanied by growth of a spiky instability in the form of stimulated Brillouin scattering.

  5. One-dimensional particle-in-cell simulation on the influence of electron and ion temperature on the sheath expansion process in the post-arc stage of vacuum circuit breaker

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mo, Yongpeng; Shi, Zongqian; Jia, Shenli

    2015-02-15

    The inter-contact region of vacuum circuit breakers is filled with residual plasma at the moment when the current is zero after the burning of metal vapor arc. The residual plasma forms an ion sheath in front of the post-arc cathode. The sheath then expands towards the post-arc anode under the influence of a transient recovery voltage. In this study, a one-dimensional particle-in-cell model is developed to investigate the post-arc sheath expansion. The influence of ion and electron temperatures on the decrease in local plasma density at the post-arc cathode side and post-arc anode side is discussed. When the decay inmore » the local plasma density develops from the cathode and anode sides into the high-density region and merges, the overall plasma density in the inter-contact region begins to decrease. Meanwhile, the ion sheath begins to expand faster. Furthermore, the theory of ion rarefaction wave only explains quantitatively the decrease in the overall plasma density at relatively low ion temperatures. With the increase of ion temperature to certain extent, another possible reason for the decrease in the overall plasma density is proposed and results from the more active thermal diffusion of plasma.« less

  6. Investigation of radiofrequency plasma sources for space travel

    NASA Astrophysics Data System (ADS)

    Charles, C.; Boswell, R. W.; Takahashi, K.

    2012-12-01

    Optimization of radiofrequency (RF) plasma sources for the development of space thrusters differs from other applications such as plasma processing of materials since power efficiency, propellant usage, particle acceleration or heating become driving parameters. The development of two RF (13.56 MHz) plasma sources, the high-pressure (˜1 Torr) capacitively coupled ‘pocket rocket’ plasma micro-thruster and the low-pressure (˜1 mTorr) inductively coupled helicon double layer thruster (HDLT), is discussed within the context of mature and emerging electric propulsion devices. The density gradient in low-pressure expanding RF plasmas creates an electric field that accelerates positive ions out of the plasma. Generally, the total potential drop is similar to that of a wall sheath allowing the plasma electrons to neutralize the ion beam. A high-pressure expansion with no applied magnetic field can result in large dissociation rates and/or a collimated beam of ions of small area and a flowing heated neutral beam (‘pocket rocket’). A low-pressure expansion dominated by a magnetic field can result in the formation of electric double layers which produce a very directed neutralized beam of ions of large area (HDLT).

  7. Use of the TLX ultracentrifuge for the isolation of different density lipoproteins and effects of freeze/thawing of human plasma before ultracentrifugation.

    PubMed

    Charlton-Menys, Valentine; Chobotova, Jelena; Durrington, Paul N

    2008-01-01

    Isolation of different density lipoproteins by ultracentrifugation can require lengthy centrifugation times and freeze/thawing of plasma may influence recovery. We isolated a range of lipoproteins using a preparative ultracentrifuge and the TLX micro-ultracentrifuge and determined the effect of freeze/thawing of plasma beforehand. In fresh plasma, there was no significant difference in results for small-dense low-density lipoprotein apolipoprotein B (LDL apoB) (density >1.044 g/mL) or cholesterol at density >1.006 g/mL. Freeze/thawing had no effect on closely correlated results for small-dense LDL apoB (r=0.85; p<0.0001) or high-density lipoprotein (r=0.93; p<0.0001). The TLX micro-ultracentrifuge is a reliable alternative to the preparative ultracentrifuge and freeze/thawing has only a small effect on small-dense LDL apoB or high-density lipoprotein cholesterol.

  8. Aronia melanocarpa (chokeberry) polyphenol-rich extract improves antioxidant function and reduces total plasma cholesterol in apolipoprotein E knockout mice.

    PubMed

    Kim, Bohkyung; Ku, Chai Siah; Pham, Tho X; Park, Youngki; Martin, Derek A; Xie, Liyang; Taheri, Rod; Lee, Jiyoung; Bolling, Bradley W

    2013-05-01

    We hypothesized that a polyphenol-rich chokeberry extract (CBE) would modulate hepatic lipid metabolism and improve antioxidant function in apolipoprotein E knockout (apoE(-/-)) mice. ApoE(-/-) mice were fed diets containing 15% fat with 0.2% cholesterol alone or supplemented with 0.005% or 0.05% CBE for 4 weeks. CBE polyphenol content was determined by the total phenols, 4-dimethylaminocinnamaldehyde, and ultra high-performance liquid chromatography-mass spectrometry methods. The 0.05% CBE diet provided mice with mean daily doses of 1.2 mg gallic acid equivalents of total phenols, 0.19 mg anthocyanins, 0.17 mg phenolic acids, 0.06 mg proanthocyanidins (as catechin-equivalents), and 0.02 mg flavonols. The 0.05% CBE group had 12% less plasma total cholesterol concentrations than the control. Despite the hypocholesterolemic effect of CBE, hepatic mRNA levels of low-density lipoprotein receptor, hydroxyl-3-methylglutaryl coenzyme A reductase and cholesterol 7α-hydroxylase in CBE-fed mice were not significantly different from controls. Dietary CBE did not alter hepatic lipid content or the hepatic expression of genes involved in lipogenesis and fatty acid β-oxidation such as fatty acid synthase, carnitine palmitoyltransferase 1 and acyl-CoA oxidase. Plasma paraoxonase and catalase activities were significantly increased in mice fed 0.05% CBE. Both CBE diets increased hepatic glutathione peroxidase (GPx) activity but the 0.05% CBE group had 24% less proximal intestine GPx activity relative to controls. Thus, dietary CBE lowered total cholesterol and improved plasma and hepatic antioxidant function at nutritionally-relevant doses in apoE(-/-) mice. Furthermore, the CBE cholesterol-lowering mechanism in apoE(-/-) mice was independent of hepatic expression of genes involved in cholesterol metabolism. Copyright © 2013 Elsevier Inc. All rights reserved.

  9. Surface density of accumulated electrons on walls in contact with a plasma

    NASA Technical Reports Server (NTRS)

    De, B. R.

    1975-01-01

    It is shown that the surface density of accumulated electrons on a wall in contact with a plasma can be expressed as a simple function of the Debye shielding distance in the plasma. The result may have applications to problems involving objects immersed in a space plasma.

  10. Nanosecond pulsed humid Ar plasma jet in air: shielding, discharge characteristics and atomic hydrogen production

    NASA Astrophysics Data System (ADS)

    Yatom, Shurik; Luo, Yuchen; Xiong, Qing; Bruggeman, Peter J.

    2017-10-01

    Gas phase non-equilibrium plasmas jets containing water vapor are of growing interest for many applications. In this manuscript, we report a detailed study of an atmospheric pressure nanosecond pulsed Ar  +  0.26% H2O plasma jet. The plasma jet operates in an atmospheric pressure air surrounding but is shielded with a coaxial argon flow to limit the air diffusion into the jet effluent core. The jet impinges on a metal plate electrode and produces a stable plasma filament (transient spark) between the needle electrode in the jet and the metal plate. The stable plasma filament is characterized by spatially and time resolved electrical and optical diagnostics. This includes Rayleigh scattering, Stark broadening of the hydrogen Balmer lines and two-photon absorption laser induced fluorescence (TaLIF) to obtain the gas temperature, the electron density and the atomic hydrogen density respectively. Electron densities and atomic hydrogen densities up to 5 × 1022 m-3 and 2 × 1022 m-3 have been measured. This shows that atomic hydrogen is one of the main species in high density Ar-H2O plasmas. The gas temperature does not exceed 550 K in the core of the plasma. To enable in situ calibration of the H TaLIF at atmospheric pressure a previously published O density calibration scheme is extended to include a correction for the line profiles by including overlap integrals as required by H TaLIF. The line width of H TaLIF, due to collision broadening has the same trend as the neutral density obtained by Rayleigh scattering. This suggests the possibility to use this technique to in situ probe neutral gas densities.

  11. Determination of plasma density from data on the ion current to cylindrical and planar probes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Voloshin, D. G., E-mail: dvoloshin@mics.msu.su; Vasil’eva, A. N.; Kovalev, A. S.

    2016-12-15

    To improve probe methods of plasma diagnostics, special probe measurements were performed and numerical models describing ion transport to a probe with allowance for collisions were developed. The current–voltage characteristics of cylindrical and planar probes were measured in an RF capacitive discharge in argon at a frequency of 81 MHz and plasma densities of 10{sup 10}–10{sup 11} cm{sup –3}, typical of modern RF reactors. 1D and 2D numerical models based on the particle-in-cell method with Monte Carlo collisions for simulating ion motion and the Boltzmann equilibrium for electrons are developed to describe current collection by a probe. The models weremore » used to find the plasma density from the ion part of the current–voltage characteristic, study the effect of ion collisions, and verify simplified approaches to determining the plasma density. A 1D hydrodynamic model of the ion current to a cylindrical probe with allowance for ion collisions is proposed. For a planar probe, a method to determine the plasma density from the averaged numerical results is developed. A comparative analysis of different approaches to calculating the plasma density from the ion current to a probe is performed.« less

  12. High energy density Z-pinch plasmas using flow stabilization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shumlak, U., E-mail: shumlak@uw.edu; Golingo, R. P., E-mail: shumlak@uw.edu; Nelson, B. A., E-mail: shumlak@uw.edu

    The ZaP Flow Z-Pinch research project[1] at the University of Washington investigates the effect of sheared flows on MHD instabilities. Axially flowing Z-pinch plasmas are produced that are 100 cm long with a 1 cm radius. The plasma remains quiescent for many radial Alfvén times and axial flow times. The quiescent periods are characterized by low magnetic mode activity measured at several locations along the plasma column and by stationary visible plasma emission. Plasma evolution is modeled with high-resolution simulation codes – Mach2, WARPX, NIMROD, and HiFi. Plasma flow profiles are experimentally measured with a multi-chord ion Doppler spectrometer. Amore » sheared flow profile is observed to be coincident with the quiescent period, and is consistent with classical plasma viscosity. Equilibrium is determined by diagnostic measurements: interferometry for density; spectroscopy for ion temperature, plasma flow, and density[2]; Thomson scattering for electron temperature; Zeeman splitting for internal magnetic field measurements[3]; and fast framing photography for global structure. Wall stabilization has been investigated computationally and experimentally by removing 70% of the surrounding conducting wall to demonstrate no change in stability behavior.[4] Experimental evidence suggests that the plasma lifetime is only limited by plasma supply and current waveform. The flow Z-pinch concept provides an approach to achieve high energy density plasmas,[5] which are large, easy to diagnose, and persist for extended durations. A new experiment, ZaP-HD, has been built to investigate this approach by separating the flow Z-pinch formation from the radial compression using a triaxial-electrode configuration. This innovation allows more detailed investigations of the sheared flow stabilizing effect, and it allows compression to much higher densities than previously achieved on ZaP by reducing the linear density and increasing the pinch current. Experimental results and scaling analyses will be presented. In addition to studying fundamental plasma science and high energy density physics, the ZaP and ZaP-HD experiments can be applied to laboratory astrophysics.« less

  13. Formation of Plasma Around a Small Meteoroid: Simulation and Theory

    NASA Astrophysics Data System (ADS)

    Sugar, G.; Oppenheim, M. M.; Dimant, Y. S.; Close, S.

    2018-05-01

    High-power large-aperture radars detect meteors by reflecting radio waves off dense plasma that surrounds a hypersonic meteoroid as it ablates in the Earth's atmosphere. If the plasma density profile around the meteoroid is known, the plasma's radar cross section can be used to estimate meteoroid properties such as mass, density, and composition. This paper presents head echo plasma density distributions obtained via two numerical simulations of a small ablating meteoroid and compares the results to an analytical solution found in Dimant and Oppenheim (2017a, https://doi.org/10.1002/2017JA023960, 2017b, https://doi.org/10.1002/2017JA023963). The first simulation allows ablated meteoroid particles to experience only a single collision to match an assumption in the analytical solution, while the second is a more realistic simulation by allowing multiple collisions. The simulation and analytical results exhibit similar plasma density distributions. At distances much less than λT, the average distance an ablated particle travels from the meteoroid before a collision with an atmospheric particle, the plasma density falls off as 1/R, where R is the distance from the meteoroid center. At distances substantially greater than λT, the plasma density profile has an angular dependence, falling off as 1/R2 directly behind the meteoroid, 1/R3 in a plane perpendicular to the meteoroid's path that contains the meteoroid center, and exp[-1.5(R/λT2/3)]/R in front of the meteoroid. When used for calculating meteoroid masses, this new plasma density model can give masses that are orders of magnitude different than masses calculated from a spherically symmetric Gaussian distribution, which has been used to calculate masses in the past.

  14. Ionospheric chemical releases

    NASA Technical Reports Server (NTRS)

    Bernhardt, Paul A.; Scales, W. A.

    1990-01-01

    Ionospheric plasma density irregularities can be produced by chemical releases into the upper atmosphere. F-region plasma modification occurs by: (1) chemically enhancing the electron number density; (2) chemically reducing the electron population; or (3) physically convecting the plasma from one region to another. The three processes (production, loss, and transport) determine the effectiveness of ionospheric chemical releases in subtle and surprising ways. Initially, a chemical release produces a localized change in plasma density. Subsequent processes, however, can lead to enhanced transport in chemically modified regions. Ionospheric modifications by chemical releases excites artificial enhancements in airglow intensities by exothermic chemical reactions between the newly created plasma species. Numerical models were developed to describe the creation and evolution of large scale density irregularities and airglow clouds generated by artificial means. Experimental data compares favorably with theses models. It was found that chemical releases produce transient, large amplitude perturbations in electron density which can evolve into fine scale irregularities via nonlinear transport properties.

  15. Optimization of laser-plasma injector via beam loading effects using ionization-induced injection

    NASA Astrophysics Data System (ADS)

    Lee, P.; Maynard, G.; Audet, T. L.; Cros, B.; Lehe, R.; Vay, J.-L.

    2018-05-01

    Simulations of ionization-induced injection in a laser driven plasma wakefield show that high-quality electron injectors in the 50-200 MeV range can be achieved in a gas cell with a tailored density profile. Using the PIC code Warp with parameters close to existing experimental conditions, we show that the concentration of N2 in a hydrogen plasma with a tailored density profile is an efficient parameter to tune electron beam properties through the control of the interplay between beam loading effects and varying accelerating field in the density profile. For a given laser plasma configuration, with moderate normalized laser amplitude, a0=1.6 and maximum electron plasma density, ne 0=4 ×1018 cm-3 , the optimum concentration results in a robust configuration to generate electrons at 150 MeV with a rms energy spread of 4% and a spectral charge density of 1.8 pC /MeV .

  16. Plasma density limits for hole boring by intense laser pulses.

    PubMed

    Iwata, Natsumi; Kojima, Sadaoki; Sentoku, Yasuhiko; Hata, Masayasu; Mima, Kunioki

    2018-02-12

    High-power lasers in the relativistic intensity regime with multi-picosecond pulse durations are available in many laboratories around the world. Laser pulses at these intensities reach giga-bar level radiation pressures, which can push the plasma critical surface where laser light is reflected. This process is referred to as the laser hole boring (HB), which is critical for plasma heating, hence essential for laser-based applications. Here we derive the limit density for HB, which is the maximum plasma density the laser can reach, as a function of laser intensity. The time scale for when the laser pulse reaches the limit density is also derived. These theories are confirmed by a series of particle-in-cell simulations. After reaching the limit density, the plasma starts to blowout back toward the laser, and is accompanied by copious superthermal electrons; therefore, the electron energy can be determined by varying the laser pulse length.

  17. Space-dependent characterization of laser-induced plasma plume during fiber laser welding

    NASA Astrophysics Data System (ADS)

    Xiao, Xianfeng; Song, Lijun; Xiao, Wenjia; Liu, Xingbo

    2016-12-01

    The role of a plasma plume in high power fiber laser welding is of considerable interest due to its influence on the energy transfer mechanism. In this study, the space-dependent plasma characteristics including spectrum intensity, plasma temperature and electron density were investigated using optical emission spectroscopy technique. The plasma temperature was calculated using the Boltzmann plot of atomic iron lines, whereas the electron density was determined from the Stark broadening of the Fe I line at 381.584 nm. Quantitative analysis of plasma characteristics with respect to the laser radiation was performed. The results show that the plasma radiation increases as the laser power increases during the partial penetration mode, and then decreases sharply after the initiation of full penetration. Both the plasma temperature and electron density increase with the increase of laser power until they reach steady state values after full penetration. Moreover, the hottest core of the plasma shifts toward the surface of the workpiece as the penetration depth increases, whereas the electron density is more evenly distributed above the surface of the workpiece. The results also indicate that the absorption and scattering of nanoparticles in the plasma plume is the main mechanism for laser power attenuation.

  18. Electron density and gas density measurements in a millimeter-wave discharge

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schaub, S. C., E-mail: sschaub@mit.edu; Hummelt, J. S.; Guss, W. C.

    2016-08-15

    Electron density and neutral gas density have been measured in a non-equilibrium air breakdown plasma using optical emission spectroscopy and two-dimensional laser interferometry, respectively. A plasma was created with a focused high frequency microwave beam in air. Experiments were run with 110 GHz and 124.5 GHz microwaves at powers up to 1.2 MW. Microwave pulses were 3 μs long at 110 GHz and 2.2 μs long at 124.5 GHz. Electron density was measured over a pressure range of 25 to 700 Torr as the input microwave power was varied. Electron density was found to be close to the critical density, where the collisional plasma frequency is equal tomore » the microwave frequency, over the pressure range studied and to vary weakly with input power. Neutral gas density was measured over a pressure range from 150 to 750 Torr at power levels high above the threshold for initiating breakdown. The two-dimensional structure of the neutral gas density was resolved. Intense, localized heating was found to occur hundreds of nanoseconds after visible plasma formed. This heating led to neutral gas density reductions of greater than 80% where peak plasma densities occurred. Spatial structure and temporal dynamics of gas heating at atmospheric pressure were found to agree well with published numerical simulations.« less

  19. Effects of combination of sibutramine and L-carnitine compared with sibutramine monotherapy on inflammatory parameters in diabetic patients.

    PubMed

    Derosa, Giuseppe; Maffioli, Pamela; Salvadeo, Sibilla A T; Ferrari, Ilaria; Gravina, Alessia; Mereu, Roberto; D'Angelo, Angela; Palumbo, Ilaria; Randazzo, Sabrina; Cicero, Arrigo F G

    2011-03-01

    The aim of the study was to evaluate the effects of 12-month treatment with sibutramine plus L-carnitine compared with sibutramine alone on body weight, glycemic control, insulin resistance, and inflammatory state in type 2 diabetes mellitus patients. Two hundred fifty-four patients with uncontrolled type 2 diabetes mellitus (glycated hemoglobin [HbA(1c)] >8.0%) in therapy with different oral hypoglycemic agents or insulin were enrolled in this study and randomized to take sibutramine 10 mg plus L-carnitine 2 g or sibutramine 10 mg in monotherapy. We evaluated at baseline and after 3, 6, 9, and 12 months these parameters: body weight, body mass index, HbA(1c), fasting plasma glucose, postprandial plasma glucose, fasting plasma insulin, homeostasis model assessment of insulin resistance index, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, leptin, tumor necrosis factor-α, adiponectin, vaspin, and high-sensitivity C-reactive protein. Sibutramine plus L-carnitine gave a faster improvement of fasting plasma glucose, postprandial plasma glucose, lipid profile, leptin, tumor necrosis factor-α, and high-sensitivity C-reactive protein compared with sibutramine alone. Furthermore, there was a better improvement of body weight, HbA(1c), fasting plasma insulin, homeostasis model assessment of insulin resistance index, vaspin, and adiponectin with sibutramine plus L-carnitine compared with sibutramine alone. Sibutramine plus L-carnitine gave a better and faster improvement of all the analyzed parameters compared with sibutramine alone without giving any severe adverse effect. Copyright © 2011 Elsevier Inc. All rights reserved.

  20. Multi-instrumental Study of Storm-induced Ionospheric Irregularities at Midlatitudes

    NASA Astrophysics Data System (ADS)

    Cherniak, I.; Zakharenkova, I.; Sokolovskiy, S. V.

    2017-12-01

    We present multi-instrumental analysis of the unusually intense plasma density irregularities occurred over European midlatitudes during geomagnetic storm of 22-23 June 2015. We combine GPS/GLONASS observations derived from the dense ground-based networks ( 1500 stations) with in situ plasma density onboard Swarm and DMSP satellites and COSMIC Radio Occultation (RO) ionospheric electron density profiles. During this geomagnetic storm, the strong ionospheric irregularities of auroral origin were registered over the Northern Europe sub-auroral and midlatitudes. Meanwhile, another kind of ionospheric irregularities of equatorial origin reached European midlatitudes from the south. The prompt penetration electric fields caused the occurrence of plasma bite-outs in the post-sunset sector over the Western Africa low latitudes and extension of the large-scale plasma bubbles toward Europe. Using GPS/GLONASS observations, the plasma bubble signatures were mapped in Europe. They were observed for more than 8 h (20-04 UT) and covered a broad area within 30o-40o N and 20o W-10o E. In this region, the steep plasma gradients, as large as 5-10 TECU/degree, and numerous embedded deep plasma depletions were developed on the background of high plasma density. For low latitude region, the bite-out signature was recognized in the form of the significantly modified shape of the COSMIC-derived ionospheric electron density profiles. These unique results were confirmed by the in situ density and upward-looking GPS data onboard the Swarm satellites at 500 km altitude, in situ density measured by DMSP and ground-based absolute TEC observations. It was found that close similarity between in situ Ne and Swarm-derived topside vertical TEC suggests that plasma density enhancements and depletions are developed in the topside ionosphere (>500 km). The intensity of plasma gradients at different altitudes was also estimated by COSMIC-based measurements of GPS signal intensity and phase fluctuations as well as by rate of TEC changes on COSMIC-GPS links. Occurrence of the plasma bubbles in Europe affected GNSS measurements over number of reference stations and led to performance degradation of SBAS EGNOS.

  1. Physiological proteins in resource-limited herbivores experiencing a population die-off

    NASA Astrophysics Data System (ADS)

    Garnier, R.; Bento, A. I.; Hansen, C.; Pilkington, J. G.; Pemberton, J. M.; Graham, A. L.

    2017-08-01

    Nutrient availability is predicted to interact with herbivore population densities. Competition for low quality food at high density may reduce summer food intake, and in turn winter survival. Conversely, low population density may favor physiological recovery through better access to better quality spring forage. Here, we take advantage of the long-term study of the Soay sheep population of St. Kilda (Scotland) to measure plasma protein markers and immunity in two consecutive summers with contrasting population densities. We show that, following a winter die-off resulting in a shift to low population density, albumin and total proteins increased, but only in adult sheep. The effect was not solely attributable to selective disappearance of malnourished sheep. Similarly, the concentration of antibodies was higher following the die-off, potentially indicating recovery of immune function. Overall, our results are consistent with the physiological recovery of surviving individuals after a harsh winter.

  2. DBD Plasma Actuators for Flow Control in Air Vehicles and Jet Engines - Simulation of Flight Conditions in Test Chambers by Density Matching

    NASA Technical Reports Server (NTRS)

    Ashpis, David E.; Thurman, Douglas R.

    2011-01-01

    Dielectric Barrier Discharge (DBD) Plasma actuators for active flow control in aircraft and jet engines need to be tested in the laboratory to characterize their performance at flight operating conditions. DBD plasma actuators generate a wall-jet electronically by creating weakly ionized plasma, therefore their performance is affected by gas discharge properties, which, in turn, depend on the pressure and temperature at the actuator placement location. Characterization of actuators is initially performed in a laboratory chamber without external flow. The pressure and temperature at the actuator flight operation conditions need to be simultaneously set in the chamber. A simplified approach is desired. It is assumed that the plasma discharge depends only on the gas density, while other temperature effects are assumed to be negligible. Therefore, tests can be performed at room temperature with chamber pressure set to yield the same density as in operating flight conditions. The needed chamber pressures are shown for altitude flight of an air vehicle and for jet engines at sea-level takeoff and altitude cruise conditions. Atmospheric flight conditions are calculated from standard atmosphere with and without shock waves. The engine data was obtained from four generic engine models; 300-, 150-, and 50-passenger (PAX) aircraft engines, and a military jet-fighter engine. The static and total pressure, temperature, and density distributions along the engine were calculated for sea-level takeoff and for altitude cruise conditions. The corresponding chamber pressures needed to test the actuators were calculated. The results show that, to simulate engine component flows at in-flight conditions, plasma actuator should be tested over a wide range of pressures. For the four model engines the range is from 12.4 to 0.03 atm, depending on the placement of the actuator in the engine. For example, if a DBD plasma actuator is to be placed at the compressor exit of a 300 PAX engine, it has to be tested at 12.4 atm for takeoff, and 6 atm for cruise conditions. If it is to be placed at the low-pressure turbine, it has to be tested at 0.5 and 0.2 atm, respectively. These results have implications for the feasibility and design of DBD plasma actuators for jet engine flow control applications. In addition, the distributions of unit Reynolds number, Mach number, and velocity along the engine are provided. The engine models are non-proprietary and this information can be used for evaluation of other types of actuators and for other purposes.

  3. Plasma Periostin Levels Are Increased in Chinese Subjects with Obesity and Type 2 Diabetes and Are Positively Correlated with Glucose and Lipid Parameters.

    PubMed

    Luo, Yuanyuan; Qu, Hua; Wang, Hang; Wei, Huili; Wu, Jing; Duan, Yang; Liu, Dan; Deng, Huacong

    2016-01-01

    The purpose of this study is to examine the relations among plasma periostin, glucose and lipid metabolism, insulin resistance and inflammation in Chinese patients with obesity (OB), and type 2 diabetes mellitus (T2DM). Plasma periostin levels in the T2DM group were significantly higher than the NGT group (P < 0.01). Patients with both OB and T2DM had the highest periostin levels. Correlation analysis showed that plasma periostin levels were positively correlated with weight, waist circumference (WC), body mass index (BMI), waist-hip ratio (WHR), fasting plasma glucose (FPG), 2 h postchallenge plasma glucose (2 h PG), glycated hemoglobin (HbA1c), triglyceride (TG), total cholesterol (TC), fasting insulin (FINS), homeostasis model assessment of insulin resistance (HOMA-IR), TNF-α, and IL-6 (P < 0.05 or 0.001) and negatively correlated with high-density lipoprotein cholesterol (HDL-C) (P < 0.001). Multiple linear regression analysis showed that TG, TNF-α, and HOMA-IR were independent related factors in influencing the levels of plasma periostin (P < 0.001). These results suggested that Chinese patients with obesity and T2DM had significantly higher plasma periostin levels. Plasma periostin levels were strongly associated with plasma TG, chronic inflammation, and insulin resistance.

  4. 2D microwave imaging reflectometer electronics.

    PubMed

    Spear, A G; Domier, C W; Hu, X; Muscatello, C M; Ren, X; Tobias, B J; Luhmann, N C

    2014-11-01

    A 2D microwave imaging reflectometer system has been developed to visualize electron density fluctuations on the DIII-D tokamak. Simultaneously illuminated at four probe frequencies, large aperture optics image reflections from four density-dependent cutoff surfaces in the plasma over an extended region of the DIII-D plasma. Localized density fluctuations in the vicinity of the plasma cutoff surfaces modulate the plasma reflections, yielding a 2D image of electron density fluctuations. Details are presented of the receiver down conversion electronics that generate the in-phase (I) and quadrature (Q) reflectometer signals from which 2D density fluctuation data are obtained. Also presented are details on the control system and backplane used to manage the electronics as well as an introduction to the computer based control program.

  5. A microwave interferometer for small and tenuous plasma density measurements.

    PubMed

    Tudisco, O; Lucca Fabris, A; Falcetta, C; Accatino, L; De Angelis, R; Manente, M; Ferri, F; Florean, M; Neri, C; Mazzotta, C; Pavarin, D; Pollastrone, F; Rocchi, G; Selmo, A; Tasinato, L; Trezzolani, F; Tuccillo, A A

    2013-03-01

    The non-intrusive density measurement of the thin plasma produced by a mini-helicon space thruster (HPH.com project) is a challenge, due to the broad density range (between 10(16) m(-3) and 10(19) m(-3)) and the small size of the plasma source (2 cm of diameter). A microwave interferometer has been developed for this purpose. Due to the small size of plasma, the probing beam wavelength must be small (λ = 4 mm), thus a very high sensitivity interferometer is required in order to observe the lower density values. A low noise digital phase detector with a phase noise of 0.02° has been used, corresponding to a density of 0.5 × 10(16) m(-3).

  6. Effects of dietary phospholipid level in cobia (Rachycentron canadum) larvae: growth, survival, plasma lipids and enzymes of lipid metabolism.

    PubMed

    Niu, J; Liu, Y J; Tian, L X; Mai, K S; Yang, H J; Ye, C X; Zhu, Y

    2008-03-01

    A study was conducted to determine the effects of dietary phospholipid (PL) levels in cobia (Rachycentron canadum) larvae with regard to growth, survival, plasma lipids and enzymes of lipid metabolism. Fish with an average weight of 0.4 g were fed diets containing four levels of PL (0, 20, 40 and 80 g kg(-1)dry matter: purity 97%) for 42 days. Final body weight (FBW), weight gain (WG) and survival ratio were highest in the 8% PL diet group and mortality was highest in PL-free diet group. We examined the activities of lipoprotein lipase (LPL) and hepatic lipase (HL) in liver, lecithin-cholesterolacyltransferase (LCAT) in plasma as well as plasma lipids and lipoprotein. LCAT activity showed a decrease of more than two-fold in PL-supplemented diet groups compared with the PL-free diet group. HL activity was highest in the 8% PL diet group and the other three groups showed no difference. LPL activity was significantly higher in the PL-supplemented diet groups than in the PL-free diet group. The dietary intervention significantly increased plasma phospholipids and total cholesterol (TC) levels, and the higher free cholesterol (FC) level contributed to the TC level. However, the fish fed PL exhibited a significantly decreased plasma triglyceride (TG) level. The lipoprotein fractions were also affected significantly by the PL. The PL-supplemented diet groups had significantly higher high-density lipoprotein (HDL) compared with the PL-free diet group, but showed a marked decrease in very low-density lipoprotein (VLDL). The results suggested that PL could modify plasma lipoprotein metabolism and lipid profile, and that the optimal dietary PL level may well exceed 80 g kg(-1) for cobia larvae according to growth and survival.

  7. Imaging Magnetospheric Perturbations of the Ionosphere/Plasmasphere System from the Ground and Space

    NASA Astrophysics Data System (ADS)

    Foster, J. C.

    2004-05-01

    The thermal plasmas of the inner magnetosphere and ionosphere move across the magnetic field under the influence of electric fields. Irrespective of their source, these electric fields extend along magnetic field lines coupling the motion of thermal plasmas in the various altitude regimes. Modern remote-sensing techniques based both on the ground and in space are providing a new view of the large and meso-scale characteristics and dynamics of the plasmas of the extended ionosphere and their importance in understanding processes and effects observed throughout the coupled spheres of Earth's upper atmosphere. During strong geomagnetic storms, disturbance electric fields uplift and redistribute the thermal plasma of the low-latitude ionosphere and inner magnetosphere, producing a pronounced poleward shift of the equatorial anomalies (EA) and enhancements of plasma concentration (total electric content, TEC) in the post-noon plasmasphere. Strong SAPS (subauroral polarization stream) electric fields erode the plasmasphere boundary layer in the region of the dusk-sector bulge, producing plasmaspheric drainage plumes which carry the high-altitude material towards the dayside magnetopause. The near-Earth footprint of these flux tubes constitutes the mid-latitude streams of storm-enhanced density (SED) which produce considerable space weather effects across the North American continent. We use ground-based GPS propagation data to produce two-dimensional maps and movies of the evolution of these TEC features as they progress from equatorial regions to the polar caps. DMSP satellite overflights provide in-situ density and plasma flow/electric field observations, while the array of incoherent scatter radars probe the altitude distribution and characteristics of these dynamic thermal plasma features. IMAGE EUV and FUV observations reveal the space-based view of spatial extent and temporal evolution of these phenomena.

  8. [Effects of APOC3 polymorphisms on the plasma lipids in healthy adolescents with different body mass index].

    PubMed

    Song, Yong-yan; Gong, Ren-rong; Zhang, Zhen; Li, Yuan-hao; Fan, Mei; Hu, Min-shan; Fang, Ding-zhi

    2015-01-01

    To investigate the possible effects of apolipoprotein C I gene (APOC3) polymorphisms on plasma lipids in healthy adolescents with different body mass index (BMI). Seven hundred and twenty three adolescents were divided into four groups according to BMI: group 1 CBMI= (17.80 +/- 0.75) kg/m2,n=180], group 2 [BMI = (19.39 +/- 0.32) kg/m2, n=182), group 3 [BMI= (20.68 +/- 0.43) kg/m2, n=1813 and group 4 [BMI= (23.40 +/- 2.05) kg/m2 ,n=180J. Fasting venous blood samples were collected, plasma lipids were determined and genome DNA was extracted for determining the genotypes of the APOC3 Sst I and -482C>T polymorphisms by PCR-RFLP. With the elevation of BMI, height and plasma high-density lipoprotein cholesterol decreased significantly (P<0.001 for both), body mass, waist circumference, hip circumference, waist/hip ratio, plasma triglycerides (TG), total cholesterol and low-density lipoprotein cholesterol levels increased significantly (P<0.001 for all). No significant differences in TG levels among Sst I genotypes were observed in group 1, group 2 and group 3; but in group 4, significant differences in TG levels among Sst I genotypes were observed, S2 carriers had higher TG levels than the adolescents with S1S1 genotype. No significant differences in plasma lipids among -482C>T genotypes were observed in all groups. The elevation of plasma TG levels by the S2 allele of APOC3 Sst I polymorphism is associated with BMI. It is possible that the reduction of body mass could favorably modulate the elevation of TG levels by S2 allele in healthy adolescents.

  9. Predawn plasma bubble cluster observed in Southeast Asia

    NASA Astrophysics Data System (ADS)

    Watthanasangmechai, Kornyanat; Yamamoto, Mamoru; Saito, Akinori; Tsunoda, Roland; Yokoyama, Tatsuhiro; Supnithi, Pornchai; Ishii, Mamoru; Yatini, Clara

    2016-06-01

    Predawn plasma bubble was detected as deep plasma depletion by GNU Radio Beacon Receiver (GRBR) network and in situ measurement onboard Defense Meteorological Satellite Program F15 (DMSPF15) satellite and was confirmed by sparse GPS network in Southeast Asia. In addition to the deep depletion, the GPS network revealed the coexisting submesoscale irregularities. A deep depletion is regarded as a primary bubble. Submesoscale irregularities are regarded as secondary bubbles. Primary bubble and secondary bubbles appeared together as a cluster with zonal wavelength of 50 km. An altitude of secondary bubbles happened to be lower than that of the primary bubble in the same cluster. The observed pattern of plasma bubble cluster is consistent with the simulation result of the recent high-resolution bubble (HIRB) model. This event is only a single event out of 76 satellite passes at nighttime during 3-25 March 2012 that significantly shows plasma depletion at plasma bubble wall. The inside structure of the primary bubble was clearly revealed from the in situ density data of DMSPF15 satellite and the ground-based GRBR total electron content.

  10. Plasma Drift Rates During and Preceding Equatorial Spread F Inferred by the HF Doppler Technique

    NASA Astrophysics Data System (ADS)

    Miller, E. S.; Hilton, A. J.; Chartier, A.

    2017-12-01

    The quiet time afternoon and evening equatorial and low-latitude ionosphere is characterized by increasing vertical drift and sharpening plasma density gradient in the lower F region. This combination of effects leads to the plasma instability cascade known imprecisely as "equatorial spread F." In this work, we utilize a simple transequatorial HF Doppler observation to infer the vertical and horizontal plasma drifts preceding and during spread-F conditions. The data exhibit three behavior regimes indicative of three different processes: The first is a slow vertical drift that may be due to either increasing vertical plasma drifts or recombination of the bottomside. The second is an explosive spread Doppler signature (indicating relative velocities of 600 m/s or more) that is associated with the initiation of the spread-F depletions. Finally, the third is a structure that represents a changing HF propagation channel as radio rays propagate through the regions of depleted-but still unstable-plasma. Observations of the March 2016 Pacific total solar eclipse will also be included as a test case for the effects of vertical drifts versus recombination.

  11. The WHISPER Relaxation Sounder and the CLUSTER Active Archive

    NASA Astrophysics Data System (ADS)

    Trotignon, J. G.; Décréau, P. M. E.; Rauch, J. L.; Vallières, X.; Rochel, A.; Kougblénou, S.; Lointier, G.; Facskó, G.; Canu, P.; Darrouzet, F.; Masson, A.

    The Waves of HIgh frequency and Sounder for Probing of Electron density by Relaxation (WHISPER) instrument is part of the Wave Experiment Consortium (WEC) of the CLUSTER mission. With the help of the long double sphere antennae of the Electric Field and Wave (EFW) instrument and the Digital Wave Processor (DWP), it delivers active (sounding) and natural (transmitter off) electric field spectra, respectively from 4 to 82 kHz, and from 2 to 80 kHz. These frequency ranges have been chosen to include the electron plasma frequency, which is closely related to the total electron density, in most of the regions encountered by the CLUSTER spacecraft. Presented here is an overview of the WHISPER data products available in the CLUSTER Active Archive (CAA). The instrument and its performance are first recalled. The way the WHISPER products are obtained is then described, with particular attention being paid to the density determination. Both sounding and natural measurements are commonly used in this process, which depends on the ambient plasma regime. This is illustrated using drawings similar to the Bryant plots commonly used in the CLUSTER master science plan. These give a clear overview of typical density values and the parts of the orbits where they are obtained. More information on the applied software or on the quality/reliability of the density determination can also be highlighted.

  12. The effect of shear flow and the density gradient on the Weibel instability growth rate in the dense plasma

    NASA Astrophysics Data System (ADS)

    Amininasab, S.; Sadighi-Bonabi, R.; Khodadadi Azadboni, F.

    2018-02-01

    Shear stress effect has been often neglected in calculation of the Weibel instability growth rate in laser-plasma interactions. In the present work, the role of the shear stress in the Weibel instability growth rate in the dense plasma with density gradient is explored. By increasing the density gradient, the shear stress threshold is increasing and the range of the propagation angles of growing modes is limited. Therefore, by increasing steps of the density gradient plasma near the relativistic electron beam-emitting region, the Weibel instability occurs at a higher stress flow. Calculations show that the minimum value of the stress rate threshold for linear polarization is greater than that of circular polarization. The Wiebel instability growth rate for linear polarization is 18.3 times circular polarization. One sees that for increasing stress and density gradient effects, there are smaller maximal growth rates for the range of the propagation angles of growing modes /π 2 < θ m i n < π and /3 π 2 < θ m i n < 2 π in circular polarized plasma and for /k c ω p < 4 in linear polarized plasma. Therefore, the shear stress and density gradient tend to stabilize the Weibel instability for /k c ω p < 4 in linear polarized plasma. Also, the shear stress and density gradient tend to stabilize the Weibel instability for the range of the propagation angles of growing modes /π 2 < θ m i n < π and /3 π 2 < θ m i n < 2 π in circular polarized plasma.

  13. Dense simple plasmas as high-temperature liquid simple metals

    NASA Technical Reports Server (NTRS)

    Perrot, F.

    1990-01-01

    The thermodynamic properties of dense plasmas considered as high-temperature liquid metals are studied. An attempt is made to show that the neutral pseudoatom picture of liquid simple metals may be extended for describing plasmas in ranges of densities and temperatures where their electronic structure remains 'simple'. The primary features of the model when applied to plasmas include the temperature-dependent self-consistent calculation of the electron charge density and the determination of a density and temperature-dependent ionization state.

  14. Native protein mapping and visualization of protein interactions in the area of human plasma high-density lipoprotein by combining nondenaturing micro 2DE and quantitative LC-MS/MS.

    PubMed

    Jin, Ya; Bu, Shujie; Zhang, Jun; Yuan, Qi; Manabe, Takashi; Tan, Wen

    2014-07-01

    A human plasma sample was subjected to nondenaturing micro 2DE and a gel area (5 mm × 18 mm) that includes high-density lipoprotein (HDL) was cut into 1 mm × 1 mm squares, then the proteins in the 90 gel pieces were analyzed by quantitative LC-MS/MS. Grid-cutting of the gel was employed to; (i) ensure the total analysis of the proteins in the area, (ii) standardize the conditions of analysis by LC-MS/MS, (iii) reconstruct the protein distribution patterns from the quantity data. Totally 154 proteins were assigned in the 90 gel pieces and the quantity distribution of each was reconstructed as a color density pattern (a native protein map). The map of apolipoprotein (Apo) A-I showed a wide apparent mass distribution characteristic to HDL and was compared with the maps of the other 153 proteins. Eleven proteins showed maps of wide distribution that overlapped with the map of Apo A-I, and all have been reported to be the components of HDL. Further, seven minor proteins associated with HDL were detected at the gel positions of high Apo A-I quantity. These results for the first time visualized the localization of HDL apolipoproteins on a nondenaturing 2DE gel and strongly suggested their interactions. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. Beneficial effects of coconut water feeding on lipid metabolism in cholesterol-fed rats.

    PubMed

    Sandhya, V G; Rajamohan, T

    2006-01-01

    The purpose of this study was to determine the effect of coconut water feeding in cholesterol-fed rats. Male albino rats were fed tender coconut water and mature coconut water at a dose level of 4 mL/100 g of body weight. Cholesterol feeding caused a marked increase in total cholesterol, very low-density lipoprotein (VLDL) + low-density lipoprotein (LDL) cholesterol, and triglycerides in serum. Administration of coconut water counteracts the increase in total cholesterol, VLDL + LDL cholesterol, and triglycerides, while high-density lipoprotein cholesterol was higher. Lipid levels in the tissues viz. liver, heart, kidney, and aorta were markedly decreased in cholesterol-fed rats supplemented with coconut water. Feeding coconut water resulted in increased activities of 3-hydroxy-3-methylglutaryl-CoA reductase in liver, lipoprotein lipase in heart and adipose tissue, and plasma lecithin:cholesterol acyl transferase, while lipogenic enzymes showed decreased activities. An increased rate of cholesterol conversion to bile acid and an increased excretion of bile acids and neutral sterols were observed in rats fed coconut water. Histopathological studies of liver and aorta revealed much less fatty accumulation in these tissues in cholesterol-fed rats supplemented with coconut water. Feeding coconut water resulted in increased plasma L-arginine content, urinary nitrite level, and nitric oxide synthase activity. These results indicate that both tender and mature coconut water has beneficial effects on serum and tissue lipid parameters in rats fed cholesterol-containing diet.

  16. Hydrodynamics simulations of 2{omega} laser propagation in underdense gasbag plasmas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meezan, N.B.; Divol, L.; Marinak, M.M.

    2004-12-01

    Recent 2{omega} laser propagation and stimulated Raman backscatter (SRS) experiments performed on the Helen laser have been analyzed using the radiation-hydrodynamics code HYDRA [M. M. Marinak, G. D. Kerbel, N. A. Gentile, O. Jones, D. Munro, S. Pollaine, T. R. Dittrich, and S. W. Haan, Phys. Plasmas 8, 2275 (2001)]. These experiments utilized two diagnostics sensitive to the hydrodynamics of gasbag targets: a fast x-ray framing camera (FXI) and a SRS streak spectrometer. With a newly implemented nonlocal thermal transport model, HYDRA is able to reproduce many features seen in the FXI images and the SRS streak spectra. Experimental andmore » simulated side-on FXI images suggest that propagation can be explained by classical laser absorption and the resulting hydrodynamics. Synthetic SRS spectra generated from the HYDRA results reproduce the details of the experimental SRS streak spectra. Most features in the synthetic spectra can be explained solely by axial density and temperature gradients. The total SRS backscatter increases with initial gasbag fill density up to {approx_equal}0.08 times the critical density, then decreases. Data from a near-backscatter imaging camera show that severe beam spray is not responsible for the trend in total backscatter. Filamentation does not appear to be a significant factor in gasbag hydrodynamics. The simulation and analysis techniques established here can be used in ongoing experimental campaigns on the Omega laser facility and the National Ignition Facility.« less

  17. Overview of ASDEX Upgrade results

    NASA Astrophysics Data System (ADS)

    Stroth, U.; Adamek, J.; Aho-Mantila, L.; Äkäslompolo, S.; Amdor, C.; Angioni, C.; Balden, M.; Bardin, S.; Barrera Orte, L.; Behler, K.; Belonohy, E.; Bergmann, A.; Bernert, M.; Bilato, R.; Birkenmeier, G.; Bobkov, V.; Boom, J.; Bottereau, C.; Bottino, A.; Braun, F.; Brezinsek, S.; Brochard, T.; Brüdgam, M.; Buhler, A.; Burckhart, A.; Casson, F. J.; Chankin, A.; Chapman, I.; Clairet, F.; Classen, I. G. J.; Coenen, J. W.; Conway, G. D.; Coster, D. P.; Curran, D.; da Silva, F.; de Marné, P.; D'Inca, R.; Douai, D.; Drube, R.; Dunne, M.; Dux, R.; Eich, T.; Eixenberger, H.; Endstrasser, N.; Engelhardt, K.; Esposito, B.; Fable, E.; Fischer, R.; Fünfgelder, H.; Fuchs, J. C.; Gál, K.; García Muñoz, M.; Geiger, B.; Giannone, L.; Görler, T.; da Graca, S.; Greuner, H.; Gruber, O.; Gude, A.; Guimarais, L.; Günter, S.; Haas, G.; Hakola, A. H.; Hangan, D.; Happel, T.; Härtl, T.; Hauff, T.; Heinemann, B.; Herrmann, A.; Hobirk, J.; Höhnle, H.; Hölzl, M.; Hopf, C.; Houben, A.; Igochine, V.; Ionita, C.; Janzer, A.; Jenko, F.; Kantor, M.; Käsemann, C.-P.; Kallenbach, A.; Kálvin, S.; Kantor, M.; Kappatou, A.; Kardaun, O.; Kasparek, W.; Kaufmann, M.; Kirk, A.; Klingshirn, H.-J.; Kocan, M.; Kocsis, G.; Konz, C.; Koslowski, R.; Krieger, K.; Kubic, M.; Kurki-Suonio, T.; Kurzan, B.; Lackner, K.; Lang, P. T.; Lauber, P.; Laux, M.; Lazaros, A.; Leipold, F.; Leuterer, F.; Lindig, S.; Lisgo, S.; Lohs, A.; Lunt, T.; Maier, H.; Makkonen, T.; Mank, K.; Manso, M.-E.; Maraschek, M.; Mayer, M.; McCarthy, P. J.; McDermott, R.; Mehlmann, F.; Meister, H.; Menchero, L.; Meo, F.; Merkel, P.; Merkel, R.; Mertens, V.; Merz, F.; Mlynek, A.; Monaco, F.; Müller, S.; Müller, H. W.; Münich, M.; Neu, G.; Neu, R.; Neuwirth, D.; Nocente, M.; Nold, B.; Noterdaeme, J.-M.; Pautasso, G.; Pereverzev, G.; Plöckl, B.; Podoba, Y.; Pompon, F.; Poli, E.; Polozhiy, K.; Potzel, S.; Püschel, M. J.; Pütterich, T.; Rathgeber, S. K.; Raupp, G.; Reich, M.; Reimold, F.; Ribeiro, T.; Riedl, R.; Rohde, V.; Rooij, G. v.; Roth, J.; Rott, M.; Ryter, F.; Salewski, M.; Santos, J.; Sauter, P.; Scarabosio, A.; Schall, G.; Schmid, K.; Schneider, P. A.; Schneider, W.; Schrittwieser, R.; Schubert, M.; Schweinzer, J.; Scott, B.; Sempf, M.; Sertoli, M.; Siccinio, M.; Sieglin, B.; Sigalov, A.; Silva, A.; Sommer, F.; Stäbler, A.; Stober, J.; Streibl, B.; Strumberger, E.; Sugiyama, K.; Suttrop, W.; Tala, T.; Tardini, G.; Teschke, M.; Tichmann, C.; Told, D.; Treutterer, W.; Tsalas, M.; Van Zeeland, M. A.; Varela, P.; Veres, G.; Vicente, J.; Vianello, N.; Vierle, T.; Viezzer, E.; Viola, B.; Vorpahl, C.; Wachowski, M.; Wagner, D.; Wauters, T.; Weller, A.; Wenninger, R.; Wieland, B.; Willensdorfer, M.; Wischmeier, M.; Wolfrum, E.; Würsching, E.; Yu, Q.; Zammuto, I.; Zasche, D.; Zehetbauer, T.; Zhang, Y.; Zilker, M.; Zohm, H.

    2013-10-01

    The medium size divertor tokamak ASDEX Upgrade (major and minor radii 1.65 m and 0.5 m, respectively, magnetic-field strength 2.5 T) possesses flexible shaping and versatile heating and current drive systems. Recently the technical capabilities were extended by increasing the electron cyclotron resonance heating (ECRH) power, by installing 2 × 8 internal magnetic perturbation coils, and by improving the ion cyclotron range of frequency compatibility with the tungsten wall. With the perturbation coils, reliable suppression of large type-I edge localized modes (ELMs) could be demonstrated in a wide operational window, which opens up above a critical plasma pedestal density. The pellet fuelling efficiency was observed to increase which gives access to H-mode discharges with peaked density profiles at line densities clearly exceeding the empirical Greenwald limit. Owing to the increased ECRH power of 4 MW, H-mode discharges could be studied in regimes with dominant electron heating and low plasma rotation velocities, i.e. under conditions particularly relevant for ITER. The ion-pressure gradient and the neoclassical radial electric field emerge as key parameters for the transition. Using the total simultaneously available heating power of 23 MW, high performance discharges have been carried out where feed-back controlled radiative cooling in the core and the divertor allowed the divertor peak power loads to be maintained below 5 MW m-2. Under attached divertor conditions, a multi-device scaling expression for the power-decay length was obtained which is independent of major radius and decreases with magnetic field resulting in a decay length of 1 mm for ITER. At higher densities and under partially detached conditions, however, a broadening of the decay length is observed. In discharges with density ramps up to the density limit, the divertor plasma shows a complex behaviour with a localized high-density region in the inner divertor before the outer divertor detaches. Turbulent transport is studied in the core and the scrape-off layer (SOL). Discharges over a wide parameter range exhibit a close link between core momentum and density transport. Consistent with gyro-kinetic calculations, the density gradient at half plasma radius determines the momentum transport through residual stress and thus the central toroidal rotation. In the SOL a close comparison of probe data with a gyro-fluid code showed excellent agreement and points to the dominance of drift waves. Intermittent structures from ELMs and from turbulence are shown to have high ion temperatures even at large distances outside the separatrix.

  18. The association between high plasma homocysteine levels and lower bone mineral density in Slovak women: the impact of vegetarian diet.

    PubMed

    Krivosíková, Zora; Krajcovicová-Kudlácková, Marica; Spustová, Viera; Stefíková, Kornélia; Valachovicová, Martina; Blazícek, Pavel; Nĕmcová, Tatiana

    2010-04-01

    A long-term vegetarian diet is generally poor in vitamin B group. The lack of vitamin B(12) together with vitamin B(6) and folate deficiency is closely related to homocysteine metabolism. Hyperhomocysteinemia was found to be associated with increased bone turnover markers and increased fracture risk. Thus, hyperhomocysteinemia, vitamin B(12) and folate deficiency may be regarded as novel risk factors for micronutrient deficiency-related osteoporosis. To assess the possible impact of a vegetarian diet on bone mineral density in cohort of Slovak vegetarian women. Fasting serum glucose, albumin, calcium, phosphorous and creatinine as well as bone markers, serum vitamin B(12), folate and plasma levels of total homocysteine were assessed in two nutritional groups (vegetarians vs. nonvegetarians) of apparently healthy women (age range 20-70 years). Bone mineral density of the femoral neck, trochanter, total femur and lumbar spine was measured in all subjects. Vegetarians had a significantly lower weight (p < 0.05), higher PTH (p < 0.01) and homocysteine (p < 0.001). Vitamin B(12) was significantly higher in nonvegetarians (p < 0.001). No differences were observed in folate levels. Univariate analysis showed significant association between homocysteine and B(12) (p < 0.01), folate (p < 0.001), creatinine (p < 0.001), total proteins (p < 0.049), age (p < 0.001) and vegetarian food intake (p < 0.001). Vegetarians had a significantly lower TrFBMD (p < 0.05) and ToFBMD (p < 0.05). Age and CTx were significant predictors in all sites of measured BMD and PTH. A strong correlation between homocysteine and FNBMD (r = -0.2009, p < 0.002), TrFBMD (r = -0.1810, p < 0.004) and ToFBMD (r = -0.2225, p < 0.001) was found in all subjects. Homocysteine is one of the predictors of bone mineral density, and hyperhomocysteinemia is associated with lower bone mineral density. In healthy adults, homocysteine levels are dependent on age as well as on nutritional habits. Thus, elderly women on a vegetarian diet seem to be at higher risk of osteoporosis development than nonvegetarian women.

  19. Lecithin has no effect on serum lipoprotein, plasma fibrinogen and macro molecular protein complex levels in hyperlipidaemic men in a double-blind controlled study.

    PubMed

    Oosthuizen, W; Vorster, H H; Vermaak, W J; Smuts, C M; Jerling, J C; Veldman, F J; Burger, H M

    1998-06-01

    To examine the effects of lecithin on serum lipoprotein, plasma fibrinogen and macro molecular protein complex (MPC) levels. Twenty free living hyperlipidaemic men participated in this double-blind study which controlled for possible indirect effects. The subjects were randomly assigned to one of three treatments: frozen yoghurt or frozen yoghurt with 20 g soya bean lecithin or frozen yoghurt with 17 g sunflower oil. Sunflower oil was used to control for the increased energy and linoleic acid intake from lecithin. Yoghurt served as the 'vehicle' for the lecithin and sunflower oil and yoghurt alone was given to one group to control for possible effects due to the yoghurt 'vehicle', as well as other environmental influences. Variables were measured with standard methods twice at baseline and after 2 and 4 weeks of treatment. Plasma linoleic acid levels increased significantly with lecithin and sunflower oil treatments indicating that compliance to the treatments were obtained. Lecithin treatment did not have significant effects on serum total cholesterol, triglyceride, high density lipoprotein cholesterol, low density lipoprotein cholesterol, apolipoprotein A, apolipoprotein B or lipoprotein (a) levels. Plasma fibrinogen and MPC levels were also not affected by lecithin therapy. Sunflower oil treatment resulted in significant increased body weight, serum TC and decreased MPC levels. Lecithin treatment had no independent effects on serum lipoprotein, plasma fibrinogen or MPC levels in hyperlipidaemic men.

  20. Diamagnetic region(s): structure of the unmagnetized plasma around Comet 67P/CG

    NASA Astrophysics Data System (ADS)

    Henri, P.; Vallières, X.; Hajra, R.; Goetz, C.; Richter, I.; Glassmeier, K.-H.; Galand, M.; Rubin, M.; Eriksson, A. I.; Nemeth, Z.; Vigren, E.; Beth, A.; Burch, J. L.; Carr, C.; Nilsson, H.; Tsurutani, B.; Wattieaux, G.

    2017-07-01

    The ESA's comet chaser Rosetta has monitored the evolution of the ionized atmosphere of comet 67P/Churyumov-Gerasimenko (67P/CG) and its interaction with the solar wind, during more than 2 yr. Around perihelion, while the cometary outgassing rate was highest, Rosetta crossed hundreds of unmagnetized regions, but did not seem to have crossed a large-scale diamagnetic cavity as anticipated. Using in situ Rosetta observations, we characterize the structure of the unmagnetized plasma found around comet 67P/CG. Plasma density measurements from RPC-MIP are analysed in the unmagnetized regions identified with RPC-MAG. The plasma observations are discussed in the context of the cometary escaping neutral atmosphere, observed by ROSINA/COPS. The plasma density in the different diamagnetic regions crossed by Rosetta ranges from ˜100 to ˜1500 cm-3. They exhibit a remarkably systematic behaviour that essentially depends on the comet activity and the cometary ionosphere expansion. An effective total ionization frequency is obtained from in situ observations during the high outgassing activity phase of comet 67P/CG. Although several diamagnetic regions have been crossed over a large range of distances to the comet nucleus (from 50 to 400 km) and to the Sun (1.25-2.4 au), in situ observations give strong evidence for a single diamagnetic region, located close to the electron exobase. Moreover, the observations are consistent with an unstable contact surface that can locally extend up to about 10 times the electron exobase.

  1. [Lack of association between the S447X variant of the lipoprotein lipase gene and plasma lipids. A preliminary study].

    PubMed

    Zambrano Morales, Mariana; Fernández Salgado, Erika; Balzán Urdaneta, Ligia; Labastidas, Neila; Aranguren-Méndez, José; Connell, Lissette; Molero Paredes, Tania; Rojas, Alicia; Panunzio, Amelia

    2014-06-01

    The increase in lipid plasma values is an important cardiovascular risk factor. Lipoprotein lipase (LPL) plays an important role in the lipoprotein metabolism and metabolic and genetic factors may influence its levels and functions. The S447X variant of the lipoprotein lipase gene is associated with changes in plasma lipids in different populations. The objective of this research was to analyze the S447X variant of the LPL gene and its relation with plasma lipids of individuals in Zulia state, Venezuela. With this purpose, we studied 75 individuals (34 men and 41 women) between 20 and 60 years of age. Each subject had a medical history which included family history, anthropometric characteristics, nutritional status evaluation and biochemical tests. Genomic DNA was extracted for the molecular study and the polymerase chain reaction was used, followed by enzyme digestion, for restriction fragments length polymorphisms using the Hinf I enzyme. The individuals studied had normal levels of blood glucose, triglycerides, total cholesterol and low density lipoproteins (LDL-C) and slightly decreased levels of high density lipoproteins (HDL-C). The genotypic distribution of the LPL gene S447X variant in the studied population was 90.6% for the homozygous genotype SS447 and 9.4% for the heterozygote SX447. The genotype 447XX was not identified. The population was found in Hardy Weinberg genetic equilibrium. No association between the S447X polymorphism of lipoprotein lipase gene and plasma lipids was observed.

  2. Size and oxidative susceptibility of low-density lipoprotein particles in breast cancer patients with tamoxifen-induced fatty liver.

    PubMed

    Wakatsuki, Akihiko; Ogawa, Yasuhiro; Saibara, Toshiji; Okatani, Yuji; Fukaya, Takao

    2002-08-01

    The purpose of the present study was to investigate the effects of tamoxifen on the size and oxidative susceptibility of low-density lipoprotein (LDL) particles in breast cancer patients with tamoxifen-induced fatty liver. We investigated the following breast cancer patients: 13 receiving no tamoxifen (group A), 13 receiving tamoxifen 40 mg daily but without fatty liver (group B), and 13 receiving tamoxifen 40 mg daily with fatty liver (group C). Plasma lipids and diameter of LDL particles were measured. Susceptibility of LDL to oxidation was analyzed by incubation with CuSO(4) while monitoring conjugated diene formation and assaying thiobarbituric acid reactive substances (TBARS). Plasma total and LDL cholesterol concentrations in groups B and C were significantly lower than those in group A. In group C, concentrations of plasma triglyceride (TG) and TBARS were significantly greater, but LDL particle diameter and lag time for LDL oxidation were significantly smaller than those in groups A and B. Plasma TG concentrations correlated negatively with computed tomography ratio of liver to spleen (r = -0.76; P < 0.001). LDL particle diameter correlated negatively with plasma TG (r = -0.62; P < 0.001) and TBARS (r = -0.44; P < 0.01), but positively with LDL lag time (r = 0.47; P < 0.01). Tamoxifen-induced fatty liver in breast cancer patients may be atherogenic, via increased TG and consequent small, easily oxidized LDL particles.

  3. The effect of a longitudinal density gradient on electron plasma wake field acceleration

    NASA Astrophysics Data System (ADS)

    Tsiklauri, David

    2016-12-01

    Three-dimensional, particle-in-cell, fully electromagnetic simulations of electron plasma wake field acceleration in the blow-out regime are presented. Earlier results are extended by (i) studying the effect of a longitudinal density gradient, (ii) avoiding the use of a co-moving simulation box, (iii) inclusion of ion motion, and (iv) studying fully electromagnetic plasma wake fields. It is established that injecting driving and trailing electron bunches into a positive density gradient of 10-fold increasing density over 10 cm long lithium vapour plasma results in spatially more compact and three times larger, compared with the uniform density case, electric fields (-6.4×1010 V m-1), leading to acceleration of the trailing bunch up to 24.4 GeV (starting from an initial 20.4 GeV), with energy transfer efficiencies from the leading to trailing bunch of 75%. In the uniform density case, a -2.5×1010 V m-1 wake is created leading to acceleration of the trailing bunch up to 22.4 GeV, with energy transfer efficiencies of 65%. It is also established that injecting the electron bunches into a negative density gradient of 10-fold decreasing density over 10 cm long plasma results in spatially more spread and two and a half smaller electric fields (-1.0×1010 V m-1), leading to a weaker acceleration of the trailing bunch up to 21.4 GeV, with energy transfer efficiencies of 45%. Taking ion motions into consideration shows that in the plasma wake ion number density can increase over a few times the background value. It is also shown that transverse electromagnetic fields in a plasma wake are of the same order as the longitudinal (electrostatic) ones.

  4. Ponderomotive perturbations of low density low-temperature plasma under laser Thomson scattering diagnostics

    NASA Astrophysics Data System (ADS)

    Shneider, Mikhail N.

    2017-10-01

    The ponderomotive perturbation in the interaction region of laser radiation with a low density and low-temperature plasma is considered. Estimates of the perturbation magnitude are determined from the plasma parameters, geometry, intensity, and wavelength of laser radiation. It is shown that ponderomotive perturbations can lead to large errors in the electron density when measured using Thomson scattering.

  5. Effects of low-dose monophasic levonorgestrel with ethinyl estradiol preparation on serum lipid levels: A twenty-four month clinical trial.

    PubMed

    Young, R L; DelConte, A

    1999-11-01

    The aim of this 24-cycle study was to evaluate the effects on serum lipid concentrations of an oral contraceptive preparation containing 100 microg levonorgestrel and 20 microg ethinyl estradiol. Forty-two healthy women were enrolled in a study designed to evaluate the effects on serum lipid concentrations of an oral contraceptive containing 100 microg levonorgestrel and 20 microg ethinyl estradiol. Lipid data were evaluated for 28 women who completed 24 cycles of treatment with a preparation of 100 microg levonorgestrel with 20 microg ethinyl estradiol for 21 days followed by placebo for 7 days. Concentrations of triglycerides, total cholesterol, high-density lipoprotein cholesterol, high-density lipoprotein cholesterol subfractions 2 and 3, low-density lipoprotein cholesterol, and apolipoproteins A-I and B were analyzed. Mean percentage changes from baseline were tested for significance by means of paired Student t tests. Total cholesterol, high-density lipoprotein cholesterol, high-density lipoprotein subfraction 2, and apolipoprotein A-I concentrations were not significantly changed from baseline. Neither was the ratio of high-density lipoprotein subfraction 2 to high-density lipoprotein subfraction 3. Mean percentage increases in concentrations of triglyceride, high-density lipoprotein subfraction 3, apolipoprotein B, and low-density lipoprotein cholesterol and increases in the ratios of total cholesterol to high-density lipoprotein cholesterol, low-density lipoprotein cholesterol to high-density lipoprotein cholesterol, and apolipoprotein B to apolipoprotein A-I were significant (P <.05) at >/=1 cycle. By cycle 24, however, only the concentration of high-density lipoprotein subfraction 3 remained significantly elevated. Changes in the plasma lipid profiles among women receiving monophasic 100 microg levonorgestrel with 20 microg ethinyl estradiol were similar to those seen with other low-dose oral contraceptives, but by cycle 24 only 1 of 7 mean values remained significantly different from baseline.

  6. Plasma Density Effects on Toroidal Flow Stabilization of Edge Localized Modes

    NASA Astrophysics Data System (ADS)

    Cheng, Shikui; Zhu, Ping; Banerjee, Debabrata

    2016-10-01

    Recent EAST experiments have demonstrated mitigation and suppression of edge localized modes (ELMs) with toroidal rotation flow in higher collisionality regime, suggesting potential roles of plasma density. In this work, the effects of plasma density on the toroidal flow stabilization of the high- n edge localized modes have been extensively studied in linear calculations for a circular-shaped limiter H-mode tokamak, using the initial-value extended MHD code NIMROD. In the single MHD model, toroidal flow has a weak stabilizing effects on the high- n modes. Such a stabilization, however, can be significantly enhanced with the increase in plasma density. Furthermore, our calculations show that the enhanced stabilization of high- n modes from toroidal flow with higher edge plasma density persists in the 2-fluid MHD model. These findings may explain the ELM mitigation and suppression by toroidal rotation in higher collisionality regime due to the enhancement of plasma density obtained in EAST experiment. Supported by the National Magnetic Confinement Fusion Program of China under Grant Nos. 2014GB124002 and 2015GB101004, the 100 Talent Program and the President International Fellowship Initiative of Chinese Academy of Sciences.

  7. Effect of platelet activating factor on endothelial permeability to plasma macromolecules

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Handley, D.A.; Arbeeny, C.M.; Lee, M.L.

    The effect of intrajugular administration of platelet activating factor (PAF-C16) on vascular permeability was examined in the guinea pig. To examine the loss of selective endothelial permeability, the extravasative effect of PAF was assessed by monitoring hemoconcentration and the plasma loss of /sup 125/I-albumin (6.7 nm), /sup 125/I-low density lipoproteins (22.0 nm) or /sup 125/I-very low density lipoproteins (62.1 nm). Extravasation was dose-dependent and began 1 min after PAF administration, continuing for 5-7 min. During extravasation, there was no evidence for selective plasma retention of any of the labeled plasma tracers, as measured by plasma radioactivity. These results suggest thatmore » PAF-induced extravasation is dose-dependent, with increases in vascular permeability sufficient to permit similar plasma efflux rates of albumin, low density lipoproteins and very low density lipoproteins.« less

  8. Harmonic plasma waves excitation and structure evolution of intense ion beams in background plasmas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hu, Zhang-Hu, E-mail: zhanghu@dlut.edu.cn; Wang, You-Nian

    2016-08-15

    The long-term dynamic evolutions of intense ion beams in plasmas have been investigated with two-dimensional electromagnetic particle simulations, taking into account the effect of the two-stream instability between beam ions and plasma electrons. Depending on the initial beam radial density profile and velocity distribution, ring structures may be formed in the beam edge regions. At the later stage of beam-plasma interactions, the ion beams are strongly modulated by the two-stream instability and multiple density spikes are formed in the longitudinal direction. The formation of these density spikes is shown to result from the excitation of harmonic plasma waves when themore » instability gets saturated. Comparisons between the beam cases with initial flat-top and Gaussian radial density profiles are made, and a higher instability growth rate is observed for the flat-top profile case.« less

  9. Investigation of surface boundary conditions for continuum modeling of RF plasmas

    NASA Astrophysics Data System (ADS)

    Wilson, A.; Shotorban, B.

    2018-05-01

    This work was motivated by a lacking general consensus in the exact form of the boundary conditions (BCs) required on the solid surfaces for the continuum modeling of Radiofrequency (RF) plasmas. Various kinds of number and energy density BCs on solid surfaces were surveyed, and how they interacted with the electric potential BC to affect the plasma was examined in two fundamental RF plasma reactor configurations. A second-order local mean energy approximation with equations governing the electron and ion number densities and the electron energy density was used to model the plasmas. Zero densities and various combinations of drift, diffusion, and thermal fluxes were considered to set up BCs. It was shown that the choice of BC can have a significant impact on the sheath and bulk plasma. The thermal and diffusion fluxes to the surface were found to be important. A pure drift BC for dielectric walls failed to produce a sheath.

  10. Mode conversion in cold low-density plasma with a sheared magnetic field

    DOE PAGES

    Dodin, I. Y.; Ruiz, D. E.; Kubo, S.

    2017-12-19

    Here, a theory is proposed that describes mutual conversion of two electromagnetic modes in cold low-density plasma, specifically, in the high-frequency limit where the ion response is negligible. In contrast to the classic (Landau–Zener-type) theory of mode conversion, the region of resonant coupling in low-density plasma is not necessarily narrow, so the coupling matrix cannot be approximated with its first-order Taylor expansion; also, the initial conditions are set up differently. For the case of strong magnetic shear, a simple method is identified for preparing a two-mode wave such that it transforms into a single-mode wave upon entering high-density plasma. Themore » theory can be used for reduced modeling of wave-power input in fusion plasmas. In particular, applications are envisioned in stellarator research, where the mutual conversion of two electromagnetic modes near the plasma edge is a known issue.« less

  11. Mode conversion in cold low-density plasma with a sheared magnetic field

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dodin, I. Y.; Ruiz, D. E.; Kubo, S.

    Here, a theory is proposed that describes mutual conversion of two electromagnetic modes in cold low-density plasma, specifically, in the high-frequency limit where the ion response is negligible. In contrast to the classic (Landau–Zener-type) theory of mode conversion, the region of resonant coupling in low-density plasma is not necessarily narrow, so the coupling matrix cannot be approximated with its first-order Taylor expansion; also, the initial conditions are set up differently. For the case of strong magnetic shear, a simple method is identified for preparing a two-mode wave such that it transforms into a single-mode wave upon entering high-density plasma. Themore » theory can be used for reduced modeling of wave-power input in fusion plasmas. In particular, applications are envisioned in stellarator research, where the mutual conversion of two electromagnetic modes near the plasma edge is a known issue.« less

  12. Electrostatic Debye layer formed at a plasma-liquid interface

    NASA Astrophysics Data System (ADS)

    Rumbach, Paul; Clarke, Jean Pierre; Go, David B.

    2017-05-01

    We construct an analytic model for the electrostatic Debye layer formed at a plasma-liquid interface by combining the Gouy-Chapman theory for the liquid with a simple parabolic band model for the plasma sheath. The model predicts a nonlinear scaling between the plasma current density and the solution ionic strength, and we confirmed this behavior with measurements using a liquid-anode plasma. Plots of the measured current density as a function of ionic strength collapse the data and curve fits yield a plasma electron density of ˜1019m-3 and an electric field of ˜104V /m on the liquid side of the interface. Because our theory is based firmly on fundamental physics, we believe it can be widely applied to many emerging technologies involving the interaction of low-temperature, nonequilibrium plasma with aqueous media, including plasma medicine and various plasma chemical synthesis techniques.

  13. The study of helicon plasma source.

    PubMed

    Miao, Ting-Ting; Zhao, Hong-Wei; Liu, Zhan-Wen; Shang, Yong; Sun, Liang-Ting; Zhang, Xue-Zhen; Zhao, Huan-Yu

    2010-02-01

    Helicon plasma source is known as efficient generator of uniform and high density plasma. A helicon plasma source was developed for investigation of plasma neutralization and plasma lens in the Institute of Modern Physics in China. In this paper, the characteristics of helicon plasma have been studied by using Langmuir four-probe and a high argon plasma density up to 3.9x10(13) cm(-3) have been achieved with the Nagoya type III antenna at the conditions of the magnetic intensity of 200 G, working gas pressure of 2.8x10(-3) Pa, and rf power of 1200 W with a frequency of 27.12 MHz. In the experiment, the important phenomena have been found: for a given magnetic induction intensity, the plasma density became greater with the increase in rf power and tended to saturation, and the helicon mode appeared at the rf power between 200 and 400 W.

  14. In vitro production of beta-very low density lipoproteins and small, dense low density lipoproteins in mildly hypertriglyceridemic plasma: role of activities of lecithin:cholester acyltransferase, cholesterylester transfer proteins and lipoprotein lipase.

    PubMed

    Chung, B H; Segrest, J P; Franklin, F

    1998-12-01

    As a model for the formation of beta-very low density lipoproteins (VLDL) and small, dense LDL by the intraplasma metabolic activities in vivo, lipoproteins in fresh plasma were interacted in vitro with endogenous lecithin:cholesterol acyltransferase (LCAT) and cholesterylester transfer proteins (CETP) and subsequently with purified lipoprotein lipase (LpL). The LCAT and CETP reactions in a mildly hypertriglyceridemic (HTG) plasma at 37 degrees C for 18 h resulted in (1) esterification of about 45% plasma unesterified cholesterol (UC), (2) a marked increase in cholesterylester (CE) (+129%) and a decrease in triglyceride (TG) (-45%) in VLDL, and (3) a marked increase of TG (+ 341%) with a small net decrease of CE (-3.6%) in LDL, causing a significant alteration in the TG/CE of VLDL (from 8.0 to 1.9) and of LDL (from 0.20 to 0.93). The LDL in LCAT and CETP-reacted plasma is larger and more buoyant than that in control plasma. In vitro lipolysis of control and LCAT and CETP-reacted plasma by LpL, which hydrolyzed >90% of VLDL-TG and about 50-60% of LDL-TG, converted most of VLDL in control plasma (>85%) but less than half (40%) of VLDL in LCAT and CETP-reacted plasma into the IDL-LDL density fraction and transformed the large, buoyant LDL in the LCAT and CETP-reacted plasma into particles smaller and denser than those in the control plasma. The remnants that accumulated in the VLDL density region of the postlipolysis LCAT and CETP-reacted plasma contained apo B-100 and E but little or no detectable apo Cs and consisted of particles having pre-beta and beta-electrophoretic mobilities. The inhibition of LCAT during incubation of plasma, which lessened the extent of alteration in VLDL and LDL core lipids, increased the extent of lipolytic removal of VLDL from the VLDL density region but lowered the extent of alteration in the size and density of LDL. The LCAT, CETP and/or LpL-mediated alterations in the density of LDL in normolipidemic fasting plasma were less pronounced than that in mildly HTG plasma, but they became highly pronounced upon increase of its TG-rich lipoprotein level by the addition of preisolated VLDL or by the induction of postprandial lipemia. Although the effect of LCAT, CETP and LpL reactions in non-circulating plasma in vitro may be different from that in vivo, the above data suggests that the plasma TG-rich lipoprotein level and the extent of intraplasma LCAT, CETP, LpL and likely hepatic lipase (HL) reactions in vivo may play a role in determining the LDL phenotype.

  15. Laser-plasma interaction experiments and diagnostics at NRL (Naval Research Laboratory). Memorandum report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ripin, B.H.; Grun, J.; Herbst, M.J.

    Laser plasma interaction experiments have now advanced to the point where very quantitative measurements are required to elucidate the physic issues important for laser fusion and other applications. Detailed time-resolved knowledge of the plasma density, temperature, velocity gradients, spatial structure, heat flow characteristics, radiation emission, etc, are needed over tremendou ranges of plasma density and temperature. Moreover, the time scales are very short, aggrevating the difficulty of the measurements further. Nonetheless, such substantial progress has been made in diagnostic development during the past few years that we are now able to do well diagnosed experiments. In this paper the authorsmore » review recent diagnostic developments for laser-plasma interactions, outline their regimes of applicability, and show examples of their utility. In addition to diagnostics for the high densities and temperature characteristic of laser fusion physics studies, diagnostics designed to study the two-stream interactions of laser created plasma flowing through an ambient low density plasma will be described.« less

  16. Local thermodynamic equilibrium in rapidly heated high energy density plasmas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aslanyan, V.; Tallents, G. J.

    Emission spectra and the dynamics of high energy density plasmas created by optical and Free Electron Lasers (FELs) depend on the populations of atomic levels. Calculations of plasma emission and ionization may be simplified by assuming Local Thermodynamic Equilibrium (LTE), where populations are given by the Saha-Boltzmann equation. LTE can be achieved at high densities when collisional processes are much more significant than radiative processes, but may not be valid if plasma conditions change rapidly. A collisional-radiative model has been used to calculate the times taken by carbon and iron plasmas to reach LTE at varying densities and heating rates.more » The effect of different energy deposition methods, as well as Ionization Potential Depression are explored. This work shows regimes in rapidly changing plasmas, such as those created by optical lasers and FELs, where the use of LTE is justified, because timescales for plasma changes are significantly longer than the times needed to achieve an LTE ionization balance.« less

  17. The influence of the Ar/O2 ratio on the electron density and electron temperature in microwave discharges

    NASA Astrophysics Data System (ADS)

    Espinho, S.; Hofmann, S.; Palomares, J. M.; Nijdam, S.

    2017-10-01

    The aim of this work is to study the properties of Ar-O2 microwave driven surfatron plasmas as a function of the Ar/O2 ratio in the gas mixture. The key parameters are the plasma electron density and electron temperature, which are estimated with Thomson scattering (TS) for O2 contents up to 50% of the total gas flow. A sharp drop in the electron density from {10}20 {{{m}}}-3 to approximately {10}18 {{{m}}}-3 is estimated as the O2 content in the gas mixture is increased up to 15%. For percentages of O2 lower than 10%, the electron temperature is estimated to be about 2-3 times higher than in the case of a pure argon discharge in the same conditions ({T}{{e}}≈ 1 eV) and gradually decreases as the O2 percentage is raised to 50%. However, for O2 percentages above 30%, the scattering spectra become Raman dominated, resulting in large uncertainties in the estimated electron densities and temperatures. The influence of photo-detached electrons from negative ions caused by the typical TS laser fluences is also likely to contribute to the uncertainty in the measured electron densities for high O2 percentages. Moreover, the detection limit of the system is reached for percentages of O2 higher than 25%. Additionally, both the electron density and temperature of microwave discharges with large Ar/O2 ratios are more sensitive to gas pressure variations.

  18. Self-consistent average-atom scheme for electronic structure of hot and dense plasmas of mixture.

    PubMed

    Yuan, Jianmin

    2002-10-01

    An average-atom model is proposed to treat the electronic structures of hot and dense plasmas of mixture. It is assumed that the electron density consists of two parts. The first one is a uniform distribution with a constant value, which is equal to the electron density at the boundaries between the atoms. The second one is the total electron density minus the first constant distribution. The volume of each kind of atom is proportional to the sum of the charges of the second electron part and of the nucleus within each atomic sphere. By this way, one can make sure that electrical neutrality is satisfied within each atomic sphere. Because the integration of the electron charge within each atom needs the size of that atom in advance, the calculation is carried out in a usual self-consistent way. The occupation numbers of electron on the orbitals of each kind of atom are determined by the Fermi-Dirac distribution with the same chemical potential for all kinds of atoms. The wave functions and the orbital energies are calculated with the Dirac-Slater equations. As examples, the electronic structures of the mixture of Au and Cd, water (H2O), and CO2 at a few temperatures and densities are presented.

  19. Lipoprotein profile, lipoprotein-associated phospholipase A2 and cardiovascular risk in hemodialysis patients.

    PubMed

    Rolla, Roberta; De Mauri, Andreana; Valsesia, Ambra; Vidali, Matteo; Chiarinotti, Doriana; Bellomo, Giorgio

    2015-12-01

    Cardiovascular disease is the leading cause of morbidity and mortality in hemodialysis patients; the increased risk of cardiovascular disease is due to accelerated atherosclerosis, inflammation and impaired lipoprotein metabolism. We aimed to evaluate lipoprotein-associated phospholipase A2 (Lp-PLA2) and some pro-inflammatory aspects of the lipoprotein profile in dialyzed patients in order to evaluate the relationship with the accelerated atherosclerosis and vascular accidents. In 102 dialysis patients and 40 non-uremic controls, we investigated the lipoprotein plasma profile, high sensitivity C-reactive protein (CRP), ceruloplasmin and serum amyloid A protein (SAA), and followed patients for 1 year to analyze the risk of acute cardiovascular events. Total cholesterol, low-density lipoprotein and high-density lipoprotein plasma levels were significantly lower in uremic patients than controls, whereas CRP, SAA, ceruloplasmin, Lp-PLA2 and their ratio with apolipoprotein A1 were significantly higher. Patients with Lp-PLA2 levels >194 nmol/min/ml had more acute cardiovascular events than patients with lower values. Our results show that in dialysis subjects: (1) low-density lipoproteins show a more atherogenic phenotype than in the general population; (2) high-density lipoproteins are less anti-inflammatory; (3) Lp-PLA2 could potentially be used to evaluate cardiovascular risk.

  20. A contoured gap coaxial plasma gun with injected plasma armature.

    PubMed

    Witherspoon, F Douglas; Case, Andrew; Messer, Sarah J; Bomgardner, Richard; Phillips, Michael W; Brockington, Samuel; Elton, Raymond

    2009-08-01

    A new coaxial plasma gun is described. The long term objective is to accelerate 100-200 microg of plasma with density above 10(17) cm(-3) to greater than 200 km/s with a Mach number above 10. Such high velocity dense plasma jets have a number of potential fusion applications, including plasma refueling, magnetized target fusion, injection of angular momentum into centrifugally confined mirrors, high energy density plasmas, and others. The approach uses symmetric injection of high density plasma into a coaxial electromagnetic accelerator having an annular gap geometry tailored to prevent formation of the blow-by instability. The injected plasma is generated by numerous (currently 32) radially oriented capillary discharges arranged uniformly around the circumference of the angled annular injection region of the accelerator. Magnetohydrodynamic modeling identified electrode profiles that can achieve the desired plasma jet parameters. The experimental hardware is described along with initial experimental results in which approximately 200 microg has been accelerated to 100 km/s in a half-scale prototype gun. Initial observations of 64 merging injector jets in a planar cylindrical testing array are presented. Density and velocity are presently limited by available peak current and injection sources. Steps to increase both the drive current and the injected plasma mass are described for next generation experiments.

  1. Density measurements in low pressure, weakly magnetized, RF plasmas: experimental verification of the sheath expansion effect

    NASA Astrophysics Data System (ADS)

    Zhang, Yunchao; Charles, Christine; Boswell, Roderick W.

    2017-07-01

    This experimental study shows the validity of Sheridan's method in determining plasma density in low pressure, weakly magnetized, RF plasmas using ion saturation current data measured by a planar Langmuir probe. The ion density derived from Sheridan's method which takes into account the sheath expansion around the negatively biased probe tip, presents a good consistency with the electron density measured by a cylindrical RF-compensated Langmuir probe using the Druyvesteyn theory. The ion density obtained from the simplified method which neglects the sheath expansion effect, overestimates the true density magnitude, e.g., by a factor of 3 to 12 for the present experiment.

  2. A Campaign to Study Equatorial Ionospheric Phenomena over Guam

    NASA Astrophysics Data System (ADS)

    Habash Krause, L.; Balthazor, R.; Dearborn, M.; Enloe, L.; Lawrence, T.; McHarg, M.; Petrash, D.; Reinisch, B. W.; Stuart, T.

    2007-05-01

    With the development of a series of ground-based and space-based experiments, the United States Air Force Academy (USAFA) is in the process of planning a campaign to investigate the relationship between equatorial ionospheric plasma dynamics and a variety of space weather effects, including: 1) ionospheric plasma turbulence in the F region, and 2) scintillation of radio signals at low latitudes. A Digisonde Portable Sounder DPS-4 will operate from the island of Guam (with a magnetic latitude of 5.6° N) and will provide measurements of ionospheric total electron content (TEC), vertical drifts of the bulk ionospheric plasma, and electron density profiles. Additionally, a dual-frequency GPS TEC/scintillation monitor will be located along the Guam magnetic meridian at a magnetic latitude of approximately 15° N. In campaign mode, we will combine these ground-based observations with those collected from space during USAFA's FalconSAT-3 and FalconSAT-5 low-earth orbit satellite missions, the first of which is scheduled to be active over a period of several months beginning in the 2007 calendar year. The satellite experiments are designed to characterize in situ irregularities in plasma density, and include measurements of bulk ion density and temperature, minority-to- majority ion mixing ratios, small scale (10 cm to 1 m) plasma turbulence, and ion distribution spectra in energy with sufficient resolution for observations of non-thermalized distributions that may be associated with velocity- space instabilities. Specific targets of investigation include: a) a comparison of plasma turbulence observed on- orbit with spread F on ionograms as measured with the Digisonde, b) a correlation between the vertical lifting of the ionospheric layer over Guam and the onset of radio scintillation activity along the Guam meridian at 15° N magnetic latitude, and c) a correlation between on-orbit turbulence and ionospheric scintillation at 15° N magnetic latitude. These relationships may provide further clues into understanding the trigger mechanisms responsible for instigating disturbances in the ionospheric plasma, thus resulting in a turbulent radio propagation medium that may cause outages of radio based communication and navigation systems.

  3. [Effect of electroacupuncture stimulation of "Fenglong" (ST 40) on expression of inflammatory cytokines of celiac macrophages in hyperlipidemia rats].

    PubMed

    Tian, Jia-Yu; Wang, Qiong; Chen, Ying-Fang; Xiao, Ying; Yue, Wei; Zhang, Hong-Xing

    2014-08-01

    To observe the effect of electroacupuncture (EA) stimulation of "Fenglong" (ST 40) on celiac inflammatory factors in rats with hyperlipemia (HLP), so as to reveal its mechanism underlying improvement of HLP. A total of 40 SD rats were randomized into normal control, high fat forage, high fat + common forage, high fat + EA, and high fat + common forage+ EA groups, with 8 rats in each group. The HLP model was established by feeding the animals with high fat forage for 28 days. EA (2 mA, 2 Hz/100 Hz) was applied to bilateral ST 40 for 30 min, once daily for 28 days. Contents of plasma total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) were detected by using an automatic biochemistry analyzer. Intercellular adhesion molecule-1 (ICAM-1), monocyte chemoattractant protein 1 (MCP-1), and interleukin-1 gamma (IL-1gamma) in macrophages of the abdominal cavity were detected using flow cytometry (FCM). Compared with the normal control group, the contents of plasma TC and LDL-C, and celiac macrophages' MCP-1, ICAM-1 and IL-1gamma contents were significantly increased in the high fat forage group and high fat + common forage group (P < 0.01). In comparison with the high fat forage group, contents of plasma TC and LDL-C, and macrophages' MCP-1, ICAM-1 and IL-1gamma were considerably down-regulated in the high fat + EA group (P < 0.01). Similarly, the levels of plasma TC and LDL-C, and macrophages' MCP-1, ICAM-1 and IL-1gamma were obviously lower in the high fat+ common forage+ EA group than in the high fat + common forage group (P < 0.01). No significant differences were found in plasma TG and HDL-C levels among the five groups (P > 0.05). EA stimulation of "Fenglong" (ST 40) has a role in down-regulating contents of plasma TC and LDL-C and celiac macrophages' MCP-1, ICAM-1 and IL-1gamma in the abdominal cavity in hyperlipemia rats, which may contribute to its effect in improving hyperlipemia.

  4. Duodenal L cell density correlates with features of metabolic syndrome and plasma metabolites.

    PubMed

    van Baar, Annieke C G; Prodan, Andrei; Wahlgren, Camilla D; Poulsen, Steen S; Knop, Filip K; Groen, Albert K; Bergman, Jacques J; Nieuwdorp, Max; Levin, Evgeni

    2018-05-01

    Enteroendocrine cells are essential for the regulation of glucose metabolism, but it is unknown whether they are associated with clinical features of metabolic syndrome (MetS) and fasting plasma metabolites. We aimed to identify fasting plasma metabolites that associate with duodenal L cell, K cell and delta cell densities in subjects with MetS with ranging levels of insulin resistance. In this cross-sectional study, we evaluated L, K and delta cell density in duodenal biopsies from treatment-naïve males with MetS using machine-learning methodology. We identified specific clinical biomarkers and plasma metabolites associated with L cell and delta cell density. L cell density was associated with increased plasma metabolite levels including symmetrical dimethylarginine, 3-aminoisobutyric acid, kynurenine and glycine. In turn, these L cell-linked fasting plasma metabolites correlated with clinical features of MetS. Our results indicate a link between duodenal L cells, plasma metabolites and clinical characteristics of MetS. We conclude that duodenal L cells associate with plasma metabolites that have been implicated in human glucose metabolism homeostasis. Disentangling the causal relation between L cells and these metabolites might help to improve the (small intestinal-driven) pathophysiology behind insulin resistance in human obesity. © 2018 The authors.

  5. Effect of discharge polarity on the propagation of atmospheric-pressure helium plasma jets and the densities of OH, NO, and O radicals.

    PubMed

    Yonemori, Seiya; Ono, Ryo

    2015-06-01

    The atmospheric-pressure helium plasma jet is an emerging technology for plasma biomedical applications. In this paper, the authors focus on the effect of discharge polarity on propagation of the discharge and the densities of OH, NO, and O radicals. The plasma jet is applied to a glass surface placed on a grounded metal plate. Positive or negative voltage pulses with 25 μs duration, 8 kV amplitude, and 10 kpps repetition rate are used for the plasma jet. The plasma propagation is measured using a short-gated ICCD camera. The light emission intensity of the discharge generated at the rising phase of the voltage pulse is approximately equivalent for both polarities, while that generated during the falling phase is much higher for the negative discharge than the positive one. The shape of the discharge changes with the discharge polarity. The OH, NO, and O densities in the plasma jet are also measured for both polarities. It is found that the OH density is almost the same regardless the discharge polarity. Conversely, the negative discharge produces more O atoms and the positive discharge produces more NO molecules. These results indicate that the polarity of the discharge affects the densities of some reactive species produced in the plasma jet.

  6. Study of ND3-enhanced MAR processes in D2-N2 plasmas to induce plasma detachment

    NASA Astrophysics Data System (ADS)

    Abe, Shota; Chakraborty Thakur, Saikat; Doerner, Russ; Tynan, George

    2017-10-01

    The Molecular Assisted Recombination (MAR) process is thought to be a main channel of volumetric recombination to induce the plasma detachment operation. Authors have focused on a new plasma recombination process supported by ammonia molecules, which will be formed by impurity seeding of N2 for controlling divertor plasma temperature and heat loads in ITER. This ammonia-enhanced MAR process would occur throughout two steps. In this study, the first step of the new MAR process is investigated in low density plasmas (Ne 1016 m-3, Te 4 eV) fueled by D2 and N2. Ion and neutral densities are measured by a calibrated Electrostatic Quadrupole Plasma (EQP) analyzer, combination of an ion energy analyzer and mass spectrometer. The EQP shows formation of ND3 during discharges. Ion densities calculated by a rate equation model are compared with experimental results. We find that the model can reproduce the observed ion densities in the plasma. The model calculation shows that the dominant neutralization channel of Dx+(x =1-3) ions in the volume is the formation of NDy+(y =3 or 4) throughout charge/D+ exchange reactions with ND3. Furthermore, high density plasmas (Ne 1016 m-3) have been achieved to investigate electron-impact dissociative recombination processes of formed NDy+,which is the second step of this MAR process.

  7. Numerical modeling of lower hybrid current drive in fully non-inductive plasma start-up experiments on TST-2

    NASA Astrophysics Data System (ADS)

    Tsujii, N.; Takase, Y.; Ejiri, A.; Shinya, T.; Togashi, H.; Yajima, S.; Yamazaki, H.; Moeller, C. P.; Roidl, B.; Sonehara, M.; Takahashi, W.; Toida, K.; Yoshida, Y.

    2017-12-01

    Non-inductive plasma start-up is a critical issue for spherical tokamaks since there is not enough room to provide neutron shielding for the center solenoid. Start-up using lower hybrid (LH) waves has been studied on the TST-2 spherical tokamak. Because of the low magnetic field of a spherical tokamak, the plasma density needs to be kept at a very low value during the plasma current ramp-up so that the plasma core remains accessible to the LH waves. However, we have found that higher density was required to sustain larger plasma current. The achievable plasma current was limited by the maximum operational toroidal field of TST-2. The existence of an optimum density for LH current drive and its toroidal field dependence is explained through a numerical simulation based on a ray tracing code and a Fokker-Planck solver. In order to access higher density at the same magnetic field, a top-launch antenna was recently installed in addition to the existing outboard-launch antenna. Increase in the density limit was observed when the power was launched from the top antenna, consistently with the numerical predictions.

  8. Ultra-High Intensity Magnetic Field Generation in Dense Plasma

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fisch, Nathaniel J.

    2014-01-08

    The main objective of this grant proposal was to explore the efficient generation of intense currents. Whereas the efficient generation of electric current in low-­energy-­density plasma has occupied the attention of the magnetic fusion community for several decades, scant attention has been paid to carrying over to high-­energy-­density plasma the ideas for steady-­state current drive developed for low-­energy-­density plasma, or, for that matter, to inventing new methodologies for generating electric current in high-­energy-­density plasma. What we proposed to do was to identify new mechanisms to accomplish current generation, and to assess the operation, physics, and engineering basis of new formsmore » of current drive in regimes appropriate for new fusion concepts.« less

  9. Electron density and plasma dynamics of a spherical theta pinch

    NASA Astrophysics Data System (ADS)

    Teske, C.; Liu, Y.; Blaes, S.; Jacoby, J.

    2012-03-01

    A spherical theta pinch for plasma stripper applications has been developed and investigated regarding the electron density and the plasma confinement during the pinching sequence. The setup consists of a 6 μH induction coil surrounding a 4000 ml spherical discharge vessel and a capacitor bank with interchangeable capacitors leading to an overall capacitance of 34 μF and 50 μF, respectively. A thyristor switch is used for driving the resonant circuit. Pulsed coil currents reached values of up to 26 kA with maximum induction of 500 mT. Typical gas pressures were 0.7 Pa up to 120 Pa with ArH2 (2.8% H2)-gas as a discharge medium. Stark broadening measurements of the Hβ emission line were carried out in order to evaluate the electron density of the discharge. In accordance with the density measurements, the transfer efficiency was estimated and a scaling law between electron density and discharge energy was established for the current setup. The densities reached values of up to 8 × 1022 m-3 for an energy of 1.6 kJ transferred into the plasma. Further, the pinching of the discharge plasma was documented and the different stages of the pinching process were analyzed. The experimental evidence suggests that concerning the recent setup of the spherical theta pinch, a linear scaling law between the transferred energy and the achievable plasma density can be applied for various applications like plasma strippers and pulsed ion sources.

  10. Development of a High Energy Density Capacitor for Plasma Thrusters.

    DTIC Science & Technology

    1980-10-01

    AD-A091 839 MAXWELL LAOS INC SAN DIEGO CA FIG 81/3 DEVELOPMENT OF A HIGH ENERGY DENSITY CAPACITOR FOR PLASMA THRUS--ETC(U) OCT 80 A RAMRUS FO*611-77...of the program was the investigation of certain capacitor impregnants and their influence on high energy density capacitors which are employed in...PERIOD 1704,60~ 13 DEVELOPMENT OF A HIGH ENERGY DENSITY CAPA- Final Technical Report CITOR FOR PLASMA THRUSTERS July 1977 - May 1980 6 PERFORMING

  11. Correlation of quantitative histopathological morphology and quantitative radiological analysis during aseptic loosening of hip endoprostheses.

    PubMed

    Bertz, S; Kriegsmann, J; Eckardt, A; Delank, K-S; Drees, P; Hansen, T; Otto, M

    2006-01-01

    Aseptic hip prosthesis loosening is the most important long-term complication in total hip arthroplasty. Polyethylene (PE) wear is the dominant etiologic factor in aseptic loosening, which together with other factors induces mechanisms resulting in bone loss, and finally in implant loosening. The single-shot radiograph analysis (EBRA, abbreviation for the German term "Einzel-Bild-Röntgenanalyse") is a computerized method for early radiological prediction of aseptic loosening. In this study, EBRA parameters were correlated with histomorphological parameters of the periprosthetic membrane. Periprosthetic membranes obtained from 19 patients during revision surgery of loosened ABG I-type total hip pros-theses were analyzed histologically and morphometrically. The pre-existing EBRA parameters, the thickness of the PE debris lay-er and the dimension of inclination and anteversion, were compared with the density of macrophages and giant cells. Addi-tionally, the semiquantitatively determined density of lymphocytes, plasma cells, giant cells and the size of the necrotic areas were correlated with the EBRA results. All periprosthetic membranes were classified as debris-induced type membranes. We found a positive correlation between the number of giant cells and the thickness of the PE debris layer. There was no significant correlation between the number of macrophages or all semiquantitative parameters and EBRA parameters. The number of giant cells decreased with implant duration. The morphometrically measured number of foreign body giant cells more closely reflects the results of the EBRA. The semiquantitative estimation of giant cell density could not substitute for the morphometrical analysis. The density of macrophages, lymphocytes, plasma cells and the size of necrotic areas did not correlate with the EBRA parameters, indicating that there is no correlation with aseptic loosening.

  12. A study of single and binary ion plasma expansion into laboratory-generated plasma wakes

    NASA Technical Reports Server (NTRS)

    Wright, Kenneth Herbert, Jr.

    1988-01-01

    Plasma expansion into the wake of a large rectangular plate immersed in a collisionless, supersonic plasma was investigated in laboratory experiments. The experimental conditions address both single ion and binary ion plasma flows for the case of a body whose size is large in comparison with the Debye length, when the potential difference between the body and the plasma is relatively small. A new plasma source was developed to generate equi-velocity, binary ion plasma flows, which allows access to new parameter space that have previously been unavailable for laboratory studies. Specifically, the new parameters are the ionic mass ratio and the ionic component density ratio. In a series of experiments, a krypton-neon plasma is employed where the ambient density ratio of neon to krypton is varied more than an order of magnitude. The expansion in both the single ion and binary ion plasma cases is limited to early times, i.e., a few ion plasma periods, by the combination of plasma density, plasma drift speed, and vacuum chamber size, which prevented detailed comparison with self-similar theory.

  13. Laser frequency modulation with electron plasma

    NASA Technical Reports Server (NTRS)

    Burgess, T. J.; Latorre, V. R.

    1972-01-01

    When laser beam passes through electron plasma its frequency shifts by amount proportional to plasma density. This density varies with modulating signal resulting in corresponding modulation of laser beam frequency. Necessary apparatus is relatively inexpensive since crystals are not required.

  14. Digital holographic interferometry employing Fresnel transform reconstruction for the study of flow shear stabilized Z-pinch plasmas.

    PubMed

    Ross, M P; Shumlak, U

    2016-10-01

    The ZaP-HD flow Z-pinch project provides a platform to explore how shear flow stabilized Z-pinches could scale to high-energy-density plasma (plasma with pressures exceeding 1 Mbar) and fusion reactor conditions. The Z-pinch is a linear plasma confinement geometry in which the plasma carries axial electric current and is confined by its self-induced magnetic field. ZaP-HD generates shear stabilized, axisymmetric Z-pinches with stable lifetimes approaching 60 μs. The goal of the project is to increase the plasma density and temperature compared to the previous ZaP project by compressing the plasma to smaller radii (≈1 mm). Radial and axial plasma electron density structure is measured using digital holographic interferometry (DHI), which provides the necessary fine spatial resolution. ZaP-HD's DHI system uses a 2 ns Nd:YAG laser pulse with a second harmonic generator (λ = 532 nm) to produce holograms recorded by a Nikon D3200 digital camera. The holograms are numerically reconstructed with the Fresnel transform reconstruction method to obtain the phase shift caused by the interaction of the laser beam with the plasma. This provides a two-dimensional map of line-integrated electron density, which can be Abel inverted to determine the local number density. The DHI resolves line-integrated densities down to 3 × 10 20 m -2 with spatial resolution near 10 μm. This paper presents the first application of Fresnel transform reconstruction as an analysis technique for a plasma diagnostic, and it analyzes the method's accuracy through study of synthetic data. It then presents an Abel inversion procedure that utilizes data on both sides of a Z-pinch local number density profile to maximize profile symmetry. Error estimation and Abel inversion are applied to the measured data.

  15. Precision Electron Density Measurements in the SSX MHD Wind Tunnel

    NASA Astrophysics Data System (ADS)

    Suen-Lewis, Emma M.; Barbano, Luke J.; Shrock, Jaron E.; Kaur, Manjit; Schaffner, David A.; Brown, Michael R.

    2017-10-01

    We characterize fluctuations of the line averaged electron density of Taylor states produced by the magnetized coaxial plasma gun of the SSX device using a 632.8 nm HeNe laser interferometer. The analysis method uses the electron density dependence of the refractive index of the plasma to determine the electron density of the Taylor states. Typical magnetic field and density values in the SSX device approach about B ≅ 0.3 T and n = 0 . 4 ×1016 cm-3 . Analysis is improved from previous density measurement methods by developing a post-processing method to remove relative phase error between interferometer outputs and to account for approximately linear phase drift due to low-frequency mechanical vibrations of the interferometer. Precision density measurements coupled with local measurements of the magnetic field will allow us to characterize the wave composition of SSX plasma via density vs. magnetic field correlation analysis, and compare the wave composition of SSX plasma with that of the solar wind. Preliminary results indicate that density and magnetic field appear negatively correlated. Work supported by DOE ARPA-E ALPHA program.

  16. Plasma density perturbation caused by probes at low gas pressure

    NASA Astrophysics Data System (ADS)

    Sternberg, Natalia; Godyak, Valery

    2017-09-01

    An analysis of plasma parameter perturbations caused by a spherical probe immersed into a spherical plasma is presented for arbitrary collisionality and arbitrary ratios of probe to plasma dimensions. The plasma was modeled by the fluid plasma equations with ion inertia and nonlinear ion friction force that dominate plasma transport at low gas pressures. Significant depletion of the plasma density around the probe surface has been found. The area of plasma depletion coincides with the sensing area of different kinds of magnetic and microwave probes and will therefore lead to errors in data inferred from measurements with such probes.

  17. Momentum balance in four solar flares

    NASA Technical Reports Server (NTRS)

    Canfield, Richard C.; Metcalf, Thomas R.; Zarro, Dominic M.; Lemen, James R.

    1990-01-01

    Solar Maximum Mission soft X-ray spectra and National Solar Observatory (Sacramento Peak) H-alpha spectra were combined in a study of high-speed flows during the impulsive phase of four solar flares. In all events, a blue asymmetry (indicative of upflows) was observed in the coronal Ca XIX line during the soft X-ray rise phase. In all events a red asymmetry (indicative of downflows) was observed simultaneously in chromospheric H-alpha. These oppositely directed flows were concurrent with impulsive hard X-ray emission. Combining the velocity data with estimates of the density based on emission measurements and volume estimates, it is shown that for the impulsive phase as a whole the total momentum of upflowing soft X-ray plasma equaled that of the downflowing H-alpha plasma, to within an order of magnitude, in all four events. Only the chromospheric evaporation model predicts equal total momentum in the upflowing soft X-ray-emitting and downflowing H-alphba-emitting materials.

  18. Staging and laser acceleration of ions in underdense plasma

    NASA Astrophysics Data System (ADS)

    Ting, Antonio; Hafizi, Bahman; Helle, Michael; Chen, Yu-Hsin; Gordon, Daniel; Kaganovich, Dmitri; Polyanskiy, Mikhail; Pogorelsky, Igor; Babzien, Markus; Miao, Chenlong; Dover, Nicholas; Najmudin, Zulfikar; Ettlinger, Oliver

    2017-03-01

    Accelerating ions from rest in a plasma requires extra considerations because of their heavy mass. Low phase velocity fields or quasi-electrostatic fields are often necessary, either by operating above or near the critical density or by applying other slow wave generating mechanisms. Solid targets have been a favorite and have generated many good results. High density gas targets have also been reported to produce energetic ions. It is interesting to consider acceleration of ions in laser-driven plasma configurations that will potentially allow continuous acceleration in multiple consecutive stages. The plasma will be derived from gaseous targets, producing plasma densities slightly below the critical plasma density (underdense) for the driving laser. Such a plasma is experimentally robust, being repeatable and relatively transparent to externally injected ions from a previous stage. When optimized, multiple stages of this underdense laser plasma acceleration mechanism can progressively accelerate the ions to a high final energy. For a light mass ion such as the proton, relativistic velocities could be reached, making it suitable for further acceleration by high phase velocity plasma accelerators to energies appropriate for High Energy Physics applications. Negatively charged ions such as antiprotons could be similarly accelerated in this multi-staged ion acceleration scheme.

  19. Measurement of electron density and electron temperature of a cascaded arc plasma using laser Thomson scattering compared to an optical emission spectroscopic approach

    NASA Astrophysics Data System (ADS)

    Yong, WANG; Cong, LI; Jielin, SHI; Xingwei, WU; Hongbin, DING

    2017-11-01

    As advanced linear plasma sources, cascaded arc plasma devices have been used to generate steady plasma with high electron density, high particle flux and low electron temperature. To measure electron density and electron temperature of the plasma device accurately, a laser Thomson scattering (LTS) system, which is generally recognized as the most precise plasma diagnostic method, has been established in our lab in Dalian University of Technology. The electron density has been measured successfully in the region of 4.5 × 1019 m-3 to 7.1 × 1020 m-3 and electron temperature in the region of 0.18 eV to 0.58 eV. For comparison, an optical emission spectroscopy (OES) system was established as well. The results showed that the electron excitation temperature (configuration temperature) measured by OES is significantly higher than the electron temperature (kinetic electron temperature) measured by LTS by up to 40% in the given discharge conditions. The results indicate that the cascaded arc plasma is recombining plasma and it is not in local thermodynamic equilibrium (LTE). This leads to significant error using OES when characterizing the electron temperature in a non-LTE plasma.

  20. Analysis of Rotation and Transport Data in C-Mod ITB Plasmas

    NASA Astrophysics Data System (ADS)

    Fiore, C. L.; Rice, J. E.; Reinke, M. L.; Podpaly, Y.; Bespamyatnov, I. O.; Rowan, W. L.

    2009-11-01

    Internal transport barriers (ITBs) spontaneously form near the half radius of Alcator C-Mod plasmas when the EDA H-mode is sustained for several energy confinement times in either off-axis ICRF heated discharges or in purely ohmic heated plasmas. These plasmas exhibit strongly peaked density and pressure profiles, static or peaking temperature profiles, peaking impurity density profiles, and thermal transport coefficients that approach neoclassical values in the core. It has long been observed that the intrinsic central plasma rotation that is strongly co-current following the H-mode transition slows and often reverses as the density peaks as the ITB forms. Recent spatial measurements demonstrate that the rotation profile develops a well in the core region that decreases continuously as central density rises while the value outside of the core remains strongly co-current. This results in the formation of a steep potential gradient/strong electric field at the location of the foot of the ITB density profile. The resulting E X B shearing rate is also quite significant at the foot. These analyses and the implications for plasma transport and stability will be presented.

  1. High Efficacy but Low Potency of δ-Opioid Receptor-G Protein Coupling in Brij-58-Treated, Low-Density Plasma Membrane Fragments.

    PubMed

    Roubalova, Lenka; Vosahlikova, Miroslava; Brejchova, Jana; Sykora, Jan; Rudajev, Vladimir; Svoboda, Petr

    2015-01-01

    HEK293 cells stably expressing PTX-insensitive δ-opioid receptor-Gi1α (C351I) fusion protein were homogenized, treated with low concentrations of non-ionic detergent Brij-58 at 0°C and fractionated by flotation in sucrose density gradient. In optimum range of detergent concentrations (0.025-0.05% w/v), Brij-58-treated, low-density membranes exhibited 2-3-fold higher efficacy of DADLE-stimulated, high-affinity [32P]GTPase and [35S]GTPγS binding than membranes of the same density prepared in the absence of detergent. The potency of agonist DADLE response was significantly decreased. At high detergent concentrations (>0.1%), the functional coupling between δ-opioid receptors and G proteins was completely diminished. The same detergent effects were measured in plasma membranes isolated from PTX-treated cells. Therefore, the effect of Brij-58 on δ-opioid receptor-G protein coupling was not restricted to the covalently bound Gi1α within δ-opioid receptor-Gi1α fusion protein, but it was also valid for PTX-sensitive G proteins of Gi/Go family endogenously expressed in HEK293 cells. Characterization of the direct effect of Brij-58 on the hydrophobic interior of isolated plasma membranes by steady-state anisotropy of diphenylhexatriene (DPH) fluorescence indicated a marked increase of membrane fluidity. The time-resolved analysis of decay of DPH fluorescence by the "wobble in cone" model of DPH motion in the membrane indicated that the exposure to the increasing concentrations of Brij-58 led to a decreased order and higher motional freedom of the dye. Limited perturbation of plasma membrane integrity by low concentrations of non-ionic detergent Brij-58 results in alteration of δ-OR-G protein coupling. Maximum G protein-response to agonist stimulation (efficacy) is increased; affinity of response (potency) is decreased. The total degradation plasma membrane structure at high detergent concentrations results in diminution of functional coupling between δ-opioid receptors and G proteins.

  2. Reducing wall plasma expansion with gold foam irradiated by laser

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Lu; Ding, Yongkun, E-mail: ding-yk@vip.sina.com; Jiang, Shaoen, E-mail: jiangshn@vip.sina.com

    The experimental study on the expanding plasma movement of low-density gold foam (∼1% solid density) irradiated by a high power laser is reported in this paper. Experiments were conducted using the SG-III prototype laser. Compared to solid gold with 19.3 g/cc density, the velocities of X-ray emission fronts moving off the wall are much smaller for gold foam with 0.3 g/cc density. Theoretical analysis and MULTI 1D simulation results also show less plasma blow-off, and that the density contour movement velocities of gold foam are smaller than those of solid gold, agreeing with experimental results. These results indicate that foam walls havemore » advantages in symmetry control and lowering plasma fill when used in ignition hohlraum.« less

  3. Preparation of synaptic plasma membrane and postsynaptic density proteins using a discontinuous sucrose gradient.

    PubMed

    Bermejo, Marie Kristel; Milenkovic, Marija; Salahpour, Ali; Ramsey, Amy J

    2014-09-03

    Neuronal subcellular fractionation techniques allow the quantification of proteins that are trafficked to and from the synapse. As originally described in the late 1960's, proteins associated with the synaptic plasma membrane can be isolated by ultracentrifugation on a sucrose density gradient. Once synaptic membranes are isolated, the macromolecular complex known as the post-synaptic density can be subsequently isolated due to its detergent insolubility. The techniques used to isolate synaptic plasma membranes and post-synaptic density proteins remain essentially the same after 40 years, and are widely used in current neuroscience research. This article details the fractionation of proteins associated with the synaptic plasma membrane and post-synaptic density using a discontinuous sucrose gradient. Resulting protein preparations are suitable for western blotting or 2D DIGE analysis.

  4. Total fluid pressure imbalance in the scrape-off layer of tokamak plasmas

    NASA Astrophysics Data System (ADS)

    Churchill, R. M.; Canik, J. M.; Chang, C. S.; Hager, R.; Leonard, A. W.; Maingi, R.; Nazikian, R.; Stotler, D. P.

    2017-04-01

    Simulations using the fully kinetic neoclassical code XGCa (X-point included guiding- center axisymmetric) were undertaken to explore the impact of kinetic effects on scrape-off layer (SOL) physics in DIII-D H-mode plasmas. XGCa is a total-f, gyrokinetic code which self-consistently calculates the axisymmetric electrostatic potential and plasma dynamics, and includes modules for Monte Carlo neutral transport. Previously presented XGCa results showed several noteworthy features, including large variations of ion density and pressure along field lines in the SOL, experimentally relevant levels of SOL parallel ion flow (Mach number  ˜ 0.5), skewed ion distributions near the sheath entrance leading to subsonic flow there, and elevated sheath potentials (Churchill 2016 Nucl. Mater. Energy 1-6). In this paper, we explore in detail the question of pressure balance in the SOL, as it was observed in the simulation that there was a large deviation from a simple total pressure balance (the sum of ion and electron static pressure plus ion inertia). It will be shown that both the contributions from the ion viscosity (driven by ion temperature anisotropy) and neutral source terms can be substantial, and should be retained in the parallel momentum equation in the SOL, but still falls short of accounting for the observed fluid pressure imbalance in the XGCa simulation results.

  5. Thermodynamics of strongly coupled repulsive Yukawa particles in ambient neutralizing plasma: Thermodynamic instability and the possibility of observation in fine particle plasmas

    NASA Astrophysics Data System (ADS)

    Totsuji, Hiroo

    2008-07-01

    The thermodynamics is analyzed for a system composed of particles with hard cores, interacting via the repulsive Yukawa potential (Yukawa particulates), and neutralizing ambient (background) plasma. An approximate equation of state is given with proper account of the contribution of ambient plasma and it is shown that there exists a possibility for the total isothermal compressibility of Yukawa particulates and ambient plasma to diverge when the coupling between Yukawa particulates is sufficiently strong. In this case, the system undergoes a transition into separated phases with different densities and we have a critical point for this phase separation. Examples of approximate phase diagrams related to this transition are given. It is emphasized that the critical point can be in the solid phase and we have the possibility to observe a solid-solid phase separation. The applicability of these results to fine particle plasmas is investigated. It is shown that, though the values of the characteristic parameters are semiquantitative due to the effects not described by this model, these phenomena are expected to be observed in fine particle plasmas, when approximately isotropic bulk systems are realized with a very strong coupling between fine particles.

  6. Generation of a wakefield undulator in plasma with transverse density gradient

    DOE PAGES

    Stupakov, Gennady V.

    2017-11-30

    Here, we show that a short relativistic electron beam propagating in a plasma with a density gradient perpendicular to the direction of motion generates a wakefield in which a witness bunch experiences a transverse force. A density gradient oscillating along the beam path would create a periodically varying force$-$an undulator, with an estimated strength of the equivalent magnetic field more than ten Tesla. This opens an avenue for creation of a high-strength, short-period undulators, which eventually may lead to all-plasma, free electron lasers where a plasma wakefield acceleration is naturally combined with a plasma undulator in a unifying, compact setup.

  7. Generation of a wakefield undulator in plasma with transverse density gradient

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stupakov, Gennady V.

    Here, we show that a short relativistic electron beam propagating in a plasma with a density gradient perpendicular to the direction of motion generates a wakefield in which a witness bunch experiences a transverse force. A density gradient oscillating along the beam path would create a periodically varying force$-$an undulator, with an estimated strength of the equivalent magnetic field more than ten Tesla. This opens an avenue for creation of a high-strength, short-period undulators, which eventually may lead to all-plasma, free electron lasers where a plasma wakefield acceleration is naturally combined with a plasma undulator in a unifying, compact setup.

  8. Plasma digital density determining device

    DOEpatents

    Sprott, Julien C.; Lovell, Thomas W.; Holly, Donald J.

    1976-01-01

    The density of a decaying plasma in an electrically conducting enclosure is determined by applying an excitation to the cavity formed by the enclosure and counting digitally the number of resonant frequencies traversed by the combination of the cavity and the decaying plasma.

  9. A parametric study of the microwave plasma-assisted combustion of premixed ethylene/air mixtures

    NASA Astrophysics Data System (ADS)

    Fuh, Che A.; Wu, Wei; Wang, Chuji

    2017-11-01

    A parametric study of microwave argon plasma assisted combustion (PAC) of premixed ethylene/air mixtures was carried out using visual imaging, optical emission spectroscopy and cavity ringdown spectroscopy as diagnostic tools. The parameters investigated included the plasma feed gas flow rate, the plasma power, the fuel equivalence ratio and the total flow rate of the fuel/air mixture. The combustion enhancement effects were characterized by the minimum ignition power, the flame length and the fuel efficiency of the combustor. It was found that: (1) increasing the plasma feed gas flow rate resulted in a decrease in the flame length, an increase in the minimum ignition power for near stoichiometric fuel equivalence ratios and a corresponding decrease in the minimum ignition power for ultra-lean and rich fuel equivalence ratios; (2) at a constant plasma power, increasing the total flow rate of the ethylene/air mixture from 1.0 slm to 1.5 slm resulted in an increase in the flame length and a reduction in the fuel efficiency; (3) increasing the plasma power resulted in a slight increase in flame length as well as improved fuel efficiency with fewer C2(d) and CH(A) radicals present downstream of the flame; (4) increasing the fuel equivalence ratio caused an increase in flame length but at a reduced fuel efficiency when plasma power was kept constant; and (5) the ground state OH(X) number density was on the order of 1015 molecules/cm3 and was observed to drop downstream along the propagation axis of the flame at all parameters investigated. Results suggest that each of the parameters independently influences the PAC processes.

  10. Thicker carotid intima-media thickness and increased plasma VEGF levels suffered by post-acute thrombotic stroke patients.

    PubMed

    Yueniwati, Yuyun; Darmiastini, Ni Komang; Arisetijono, Eko

    2016-01-01

    Atherosclerosis causes reduction of the oxygen supply to structures in the far arterial wall, provoking the release of factors that drive angiogenesis of vasa vasorum, including VEGF. Other studies have revealed the inflammatory response in atherosclerosis and the role of platelet factor 4 (PF4) as an anti-angiogenic chemokine through the inhibition of VEGF. This cross-sectional study aims at measuring the effect of atherosclerosis assessed through carotid intima-media thickness (CIMT) against plasma VEGF levels in patients with post-acute thrombotic stroke. CIMT was assessed sonographically using GE Logiq S6 with 13 MHz frequency linear probe. VEGF-A plasma levels were measured using enzyme-linked immunosorbent assay (ELISA) method. Differences among variables were compared statistically. The data were analyzed using Pearson correlation. A total of 25 patients with post-acute thrombotic stroke were identified in days 7 to 90. CIMT thickening was indicated in 88% of patients (1.202 ± 0.312 mm), while an increase in plasma VEGF was identified in all patients (178.28 ± 93.96 ng/mL). There was no significant correlation between CIMT and plasma VEGF levels in patients with post-acute thrombotic stroke ( p =0.741). A significant correlation was recognized between CIMT and total cholesterol ( p =0.029) and low-density lipoprotein ( p =0.018). There were no significant correlations between CIMT and plasma VEGF levels in patients with post-acute thrombotic stroke. However, plasma VEGF increased in patients with thrombotic stroke. CIMT measurement is a promising noninvasive modality to assess the vascular condition of patients with stroke and diabetes, while plasma VEGF cannot specifically assess vascular condition as it can be triggered by ischemic conditions in tissues of the whole body.

  11. Radiation source

    DOEpatents

    Thode, Lester E.

    1981-01-01

    A device and method for relativistic electron beam heating of a high-density plasma in a small localized region. A relativistic electron beam generator or accelerator produces a high-voltage electron beam which propagates along a vacuum drift tube and is modulated to initiate electron bunching within the beam. The beam is then directed through a low-density gas chamber which provides isolation between the vacuum modulator and the relativistic electron beam target. The relativistic beam is then applied to a high-density target plasma which typically comprises DT, DD, or similar thermonuclear gas at a density of 10.sup.17 to 10.sup.20 electrons per cubic centimeter. The target gas is ionized prior to application of the relativistic electron beam by means of a laser or other preionization source to form a plasma. Utilizing a relativistic electron beam with an individual particle energy exceeding 3 MeV, classical scattering by relativistic electrons passing through isolation foils is negligible. As a result, relativistic streaming instabilities are initiated within the high-density target plasma causing the relativistic electron beam to efficiently deposit its energy into a small localized region of the high-density plasma target.

  12. RF attenuation as a dusty plasma diagnostic

    NASA Astrophysics Data System (ADS)

    Doyle, Brandon; Konopka, Uwe; Thomas, Edward

    2017-10-01

    When a dusty plasma is formed by adding dust to a plasma environment, the electron density of the background plasma is depleted as the dust particles acquire their negative charge. The magnitude of the electron depletion depends on the dust particle charge, and thus its properties, as well as the dust number density. A direct measurement of the electron density in a dusty plasma therefore contains information about the charging state of the dust particles. This measurement is difficult to obtain without influencing the system. For example, Langmuir probes influence the system by creating voids, or they become unreliable due to their potential contamination with dust. A less invasive diagnostic tool might be realized using plasma chamber electrodes for a plasma impedance measurement as it depends on the excitation frequency: the spatially averaged electron density is derived from the electron plasma frequency, which is related to the radio frequency attenuation characteristic. We present preliminary experiments using two impedance probe designs: probes immersed in a plasma and electrodes located at the edge of the plasma. We evaluate the potential application of this method for ground-based laboratory experiments and future microgravity experiment facilities aboard the ISS. This work was supported by JPL/NASA (JPL-RSA 1571699) the US Dept. of Energy (DE-SC0016330) and NSF (PHY-1613087).

  13. Analytical and experimental investigation of the coaxial plasma gun for use as a particle accelerator

    NASA Technical Reports Server (NTRS)

    Shriver, E. L.

    1972-01-01

    The coaxial plasma accelerator for use as a projectile accelerator is discussed. The accelerator is described physically and analytically by solution of circuit equations, and by solving for the magnetic pressures which are formed by the j cross B vector forces on the plasma. It is shown that the plasma density must be increased if the accelerator is to be used as a projectile accelerator. Three different approaches to increasing plasma density are discussed. When a magnetic field containment scheme was used to increase the plasma density, glass beads of 0.66 millimeter diameter were accelerated to 7 to 8 kilometers per second velocities. Glass beads of smaller diameter were accelerated to more than twice this velocity.

  14. Impact of Gas Heating in Inductively Coupled Plasmas

    NASA Technical Reports Server (NTRS)

    Hash, D. B.; Bose, D.; Rao, M. V. V. S.; Cruden, B. A.; Meyyappan, M.; Sharma, S. P.; Biegel, Bryan (Technical Monitor)

    2001-01-01

    Recently it has been recognized that the neutral gas in inductively coupled plasma reactors heats up significantly during processing. The resulting gas density variations across the reactor affect reaction rates, radical densities, plasma characteristics, and uniformity within the reactor. A self-consistent model that couples the plasma generation and transport to the gas flow and heating has been developed and used to study CF4 discharges. A Langmuir probe has been used to measure radial profiles of electron density and temperature. The model predictions agree well with the experimental results. As a result of these comparisons along with the poorer performance of the model without the gas-plasma coupling, the importance of gas heating in plasma processing has been verified.

  15. Controllable robust laser driven ion acceleration from near-critical density relativistic self-transparent plasma

    NASA Astrophysics Data System (ADS)

    Liu, Bin; Meyer-Ter-Vehn, Juergen; Ruhl, Hartmut

    2017-10-01

    We introduce an alternative approach for laser driven self-injected high quality ion acceleration. We call it ion wave breaking acceleration. It operates in relativistic self-transparent plasma for ultra-intense ultra-short laser pulses. Laser propagating in a transparent plasma excites an electron wave as well as an ion wave. When the ion wave breaks, a fraction of ions is self-injected into the positive part of the laser driven wake. This leads to a superior ion pulse with peaked energy spectra; in particular in realistic three-dimensional geometry, the injection occurs localized close to the laser axis producing highly directed bunches. A theory is developed to investigate the ion wave breaking dynamics. Three dimensional Particle-in-Cell simulations with pure-gaussian laser pulses and pre-expanded near-critical density plasma targets have been done to verify the theoretical results. It is shown that hundreds of MeV, easily controllable and manipulable, micron-scale size, highly collimated and quasi-mono-energetic ion beams can be produced by using ultra-intense ultra-short laser pulses with total laser energies less than 10 Joules. Such ion beams may find important applications in tumour therapy. B. Liu acknowledges support from the Alexander von Humboldt Foundation. B. Liu and H. Ruhl acknowledge supports from the Gauss Centre for Supercomputing (GCS), and the Cluster-of-Excellence Munich Centre for Advanced Photonics (MAP).

  16. Thyroid function status and plasma lipids among cardiology patients in Georgia.

    PubMed

    Chapidze, G; Enquobahrie, D; Kapanadze, S; Dolidze, N; Soh, J; Williams, M

    2007-01-01

    Thyroid dysfunction as an important cardiovascular risk factor, is not well characterized among cardiology patients of Georgia. Further, a consensus has not been reached about the relationships between thyroid function markers and plasma lipids. We investigated these risk factors among 250 cardiology patients admitted to the Emergency Cardiology Center. A cross sectional study was conducted using in-person interviews, medical records, physical exams and laboratory studies. Thyroid stimulating hormone, free thyroxine 3, free thyroxine 4 and plasma lipids were measured using standardized assays. Overall, thyroid dysfunction was detected among 28.6% of the study population (19.5% males and 39.6% females). Overt hypo- and hyperthyroidism were present among 12.4% and 6.0% of patients, while, subclinical hypo- and hyperthyroidism were present among 2.8% and 6.4% of patients respectively. Both clinical and subclinical hypothyroidism were associated with elevated total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) concentrations (p-values for trend <0.005). Further, TC and LDL-C were highly correlated with thyroid function markers (all p-values <0.000). Triglycerides and high-density lipoprotein cholesterol concentrations were not associated with thyroid function status. Hyperthyroidism was not associated with plasma lipid variation. thyroid dysfunction was prevalent among cardiology patients in Georgia. Hypothyroidism was associated with elevated TC and LDL-C concentrations. Future studies that examine the clinical relevance of observed differences in lipid profiles among this population are needed.

  17. Systemic delivery of estradiol, but not testosterone or progesterone, alters very low density lipoprotein-triglyceride kinetics in postmenopausal women.

    PubMed

    Smith, Gordon I; Reeds, Dominic N; Okunade, Adewole L; Patterson, Bruce W; Mittendorfer, Bettina

    2014-07-01

    Sexual dimorphism in plasma triglyceride (TG) metabolism is well established but it is unclear to what extent it is driven by differences in the sex hormone milieu. RESULTS from previous studies evaluating the effects of sex steroids on plasma TG homeostasis are inconclusive because they relied on orally administered synthetic hormone preparations or evaluated only plasma lipid concentrations but not kinetics. The purpose of this study was to evaluate the effects of systemically delivered 17β-estradiol, progesterone, and T on very low density lipoprotein-triglyceride (VLDL-TG) concentration and kinetics in postmenopausal women. VLDL-TG concentration and kinetics were evaluated by using stable isotope-labeled tracer techniques in four groups of postmenopausal women (n = 27 total) who were studied before and after treatment with either 17β-estradiol (0.1 mg/d via continuous delivery skin patch), progesterone (100 mg/d via vaginal insert) and T (12.5 mg/d via skin gel), or no intervention (control group). VLDL-TG concentration and kinetics were unchanged in the control group and not altered by T and progesterone administration. Estradiol treatment, in contrast, reduced VLDL-TG concentration by approximately 30% due to accelerated VLDL-TG plasma clearance (25.1 ± 2.5 vs. 17.4 ± 2.7 mL/min; P < .01). Estradiol, but not progesterone or T, is a major regulator of VLDL-TG metabolism.

  18. Electron dynamics in high energy density plasma bunch generation driven by intense picosecond laser pulse

    NASA Astrophysics Data System (ADS)

    Li, M.; Yuan, T.; Xu, Y. X.; Luo, S. N.

    2018-05-01

    When an intense picosecond laser pulse is loaded upon a dense plasma, a high energy density plasma bunch, including electron bunch and ion bunch, can be generated in the target. We simulate this process through one-dimensional particle-in-cell simulation and find that the electron bunch generation is mainly due to a local high energy density electron sphere originated in the plasma skin layer. Once generated the sphere rapidly expands to compress the surrounding electrons and induce high density electron layer, coupled with that, hot electrons are efficiently triggered in the local sphere and traveling in the whole target. Under the compressions of light pressure, forward-running and backward-running hot electrons, a high energy density electron bunch generates. The bunch energy density is as high as TJ/m3 order of magnitude in our conditions, which is significant in laser driven dynamic high pressure generation and may find applications in high energy density physics.

  19. Plasma Flow During RF Discharges in VASIMR

    NASA Technical Reports Server (NTRS)

    Jacobson, V. T.; Chang Diaz, F. R.; Squire, J. P.; Ilin, A. V.; Bengtson, R. D.; Carter, M. D.; Goulding, R. H.

    1999-01-01

    The Variable Specific Impulse Magnetoplasma Rocket (VASIMR) plasma source consists of a helical antenna, driven at frequencies of 4 to 19 MHz with powers up to 1 kW, in a magnetic field up to 3 kG. Helium is the current test gas, and future experiments with hydrogen are planned. Plasma density and temperature profiles were measured by a reciprocating Langmuir probe, and plasma flow profiles were measured with a reciprocating Mach probe. Both probes were located about 0.5 m downstream from the helical antenna. The plasma source operated in capacitive and inductive modes in addition to a helicon mode. During capacitive and inductive modes, densities were low and plasma flow was < 0.5 Cs. When the plasma operated in a helicon mode, the densities measured downstream from the source were higher [10(exp 12) / cubic cm ] and plasma flow along the magnetic field was of the order Mach 1. Details of the measurements will be shown.

  20. Space-Time Characterization of Laser Plasma Interactions in the Warm Dense Matter Regime

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cao, L F; Uschmann, I; Forster, E

    2008-04-30

    Laser plasma interaction experiments have been performed using a fs Titanium Sapphire laser. Plasmas have been generated from planar PMMA targets using single laser pulses with 3.3 mJ pulse energy, 50 fs pulse duration at 800 nm wavelength. The electron density distributions of the plasmas in different delay times have been characterized by means of Nomarski Interferometry. Experimental data were compared with hydrodynamic simulation. First results to characterize the plasma density and temperature as a function of space and time are obtained. This work aims to generate plasmas in the warm dense matter (WDM) regime at near solid-density in anmore » ultra-fast laser target interaction process. Plasmas under these conditions can serve as targets to develop x-ray Thomson scattering as a plasma diagnostic tool, e.g., using the VUV free-electron laser (FLASH) at DESY Hamburg.« less

  1. Spectroscopic measurements of plasma emission light for plasma-based acceleration experiments

    NASA Astrophysics Data System (ADS)

    Filippi, F.; Anania, M. P.; Biagioni, A.; Chiadroni, E.; Cianchi, A.; Ferrario, M.; Mostacci, A.; Palumbo, L.; Zigler, A.

    2016-09-01

    Advanced particle accelerators are based on the excitation of large amplitude plasma waves driven by either electron or laser beams. Future experiments scheduled at the SPARC_LAB test facility aim to demonstrate the acceleration of high brightness electron beams through the so-called resonant Plasma Wakefield Acceleration scheme in which a train of electron bunches (drivers) resonantly excites wakefields into a preformed hydrogen plasma; the last bunch (witness) injected at the proper accelerating phase gains energy from the wake. The quality of the accelerated beam depends strongly on plasma density and its distribution along the acceleration length. The measurements of plasma density of the order of 1016-1017 cm-3 can be performed with spectroscopic measurements of the plasma-emitted light. The measured density distribution for hydrogen filled capillary discharge with both Balmer alpha and Balmer beta lines and shot-to-shot variation are here reported.

  2. Radiation characteristics of input power from surface wave sustained plasma antenna

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Naito, T., E-mail: Naito.Teruki@bc.MitsubishiElectric.co.jp; Yamaura, S.; Fukuma, Y.

    This paper reports radiation characteristics of input power from a surface wave sustained plasma antenna investigated theoretically and experimentally, especially focusing on the power consumption balance between the plasma generation and the radiation. The plasma antenna is a dielectric tube filled with argon and small amount of mercury, and the structure is a basic quarter wavelength monopole antenna at 2.45 GHz. Microwave power at 2.45 GHz is supplied to the plasma antenna. The input power is partially consumed to sustain the plasma, and the remaining part is radiated as a signal. The relationship between the antenna gain and the input powermore » is obtained by an analytical derivation and numerical simulations. As a result, the antenna gain is kept at low values, and most of the input power is consumed to increase the plasma volume until the tube is filled with the plasma whose electron density is higher than the critical electron density required for sustaining the surface wave. On the other hand, the input power is consumed to increase the electron density after the tube is fully filled with the plasma, and the antenna gain increases with increasing the electron density. The dependence of the antenna gain on the electron density is the same as that of a plasma antenna sustained by a DC glow discharge. These results are confirmed by experimental results of the antenna gain and radiation patterns. The antenna gain of the plasma is a few dB smaller than that of the identical metal antenna. The antenna gain of the plasma antenna is sufficient for the wireless communication, although it is difficult to substitute the plasma antenna for metal antennas completely. The plasma antenna is suitable for applications having high affinity with the plasma characteristics such as low interference and dynamic controllability.« less

  3. Temporal-spatial measurement of electron relaxation time in femtosecond laser induced plasma using two-color pump-probe imaging technique

    NASA Astrophysics Data System (ADS)

    Pan, Changji; Jiang, Lan; Wang, Qingsong; Sun, Jingya; Wang, Guoyan; Lu, Yongfeng

    2018-05-01

    The femtosecond (fs) laser is a powerful tool to study ultrafast plasma dynamics, especially electron relaxation in strong ionization of dielectrics. Herein, temporal-spatial evolution of femtosecond laser induced plasma in fused silica was investigated using a two-color pump-probe technique (i.e., 400 nm and 800 nm, respectively). We demonstrated that when ionized electron density is lower than the critical density, free electron relaxation time is inversely proportional to electron density, which can be explained by the electron-ion scattering regime. In addition, electron density evolution within plasma was analyzed in an early stage (first 800 fs) of the laser-material interaction.

  4. Reduced aortic lesions and elevated high density lipoprotein levels in transgenic mice overexpressing mouse apolipoprotein A-IV.

    PubMed Central

    Cohen, R D; Castellani, L W; Qiao, J H; Van Lenten, B J; Lusis, A J; Reue, K

    1997-01-01

    Transgenic mouse lines carrying several copies of the mouse apo A-IV gene were produced. Lipoprotein composition and function, and aortic lesion development were examined. Apo A-IV levels in the plasma of transgenic mice were elevated threefold compared with nontransgenic littermates on a chow diet, and sixfold in mice fed an atherogenic diet. Plasma concentrations of total cholesterol, HDL cholesterol, triglycerides, and free fatty acids were similar in transgenic and control mice fed a chow diet. However, with the atherogenic diet, male transgenic mice exhibited significantly higher levels of plasma triglycerides (P < 0.05), total cholesterol (P < 0.01), HDL cholesterol (P < 0.0001), and free fatty acids (P < 0.05), and lower levels of unesterified cholesterol (P < 0.05), than nontransgenic littermates. Expression of the apo A-IV transgene had a protective effect against the formation of diet-induced aortic lesions, with transgenics exhibiting lesion scores of approximately 30% those seen in control mice. HDL-sized lipoproteins isolated from transgenic mice fed the atherogenic diet promoted cholesterol efflux from cholesterol-loaded human monocytes more efficiently than comparable lipoproteins from nontransgenic counterparts. Plasma from transgenics also exhibited higher endogenous cholesterol esterification rates. Taken together, these results suggest that apo A-IV levels influence the metabolism and antiatherogenic properties of HDL. PMID:9109435

  5. Effects of dietary amylose/amylopectin ratio on growth performance, feed utilization, digestive enzymes, and postprandial metabolic responses in juvenile obscure puffer Takifugu obscurus.

    PubMed

    Liu, Xiang-he; Ye, Chao-xia; Ye, Ji-dan; Shen, Bi-duan; Wang, Chun-yan; Wang, An-li

    2014-10-01

    The effect of dietary amylose/amylopectin (AM/AP) ratio on growth, feed utilization, digestive enzyme activities, plasma parameters, and postprandial blood glucose responses was evaluated in juvenile obscure puffer, Takifugu obscurus. Five isonitrogenous (430 g kg(-1) crude protein) and isolipidic (90 g kg(-1) crude lipid) diets containing an equal starch level (250 g kg(-1) starch) with different AM/AP ratio diets of 0/25, 3/22, 6/19, 9/16 and 12/13 were formulated. Each experimental diet was fed to triplicate groups (25 fish per tank), twice daily during a period of 60 days. After the growth trial, a postprandial blood response test was carried out. Fish fed diet 6/19 showed best growth, feed efficiency and protein efficiency ratio. Hepatosomatic index, plasma total cholesterol concentration, liver glycogen and lipid content, and gluconokinase, pyruvate kinase and fructose-1,6-bisphosphatase activities were lower in fish fed highest AM/AP diet (12/13) than in fish fed the low-amylose diets. Activities of liver and intestinal trypsin in fish fed diet 3/22 and diet 6/19 were higher than in fish fed diet 9/16 and diet 12/13. Activities of liver and intestinal amylase and intestinal lipase, and starch digestibility were negatively correlated with dietary AM/AP ratio. Fish fed diet 3/22 and diet 6/19 showed higher plasma total amino acid concentration than fish fed the other diets, while plasma urea nitrogen concentration and activities of alanine aminotransferase and aspartate aminotransferase showed the opposite trend. Equal values were found for viscerosomatic index and condition factor, whole body and muscle composition, plasma high-density and low-density lipoprotein cholesterol concentrations, and activities of lipase and hexokinase and glucose-6-phosphatase in liver. Postprandial plasma glucose and triglyceride peak value of fish fed diet 12/13 were lower than in fish fed the low-amylose diets, and the peak time of plasma glucose was later than in fish fed the other diets. Plasma glucose and triglyceride concentrations showed a significant difference at 2 and 4 h after a meal and varied between dietary treatments. According to regression analysis of weight gain against dietary AM/AP ratio, the optimum dietary AM/AP ratio for maximum growth of obscure puffer was 0.25. The present result indicates that dietary AM/AP ratio could affect growth performance and feed utilization, some plasma parameters, digestive enzyme as well as hepatic glucose metabolic enzyme activities in juvenile obscure puffer.

  6. Plasma and cyclotron frequency effects on output power of the plasma wave-pumped free-electron lasers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zolghadr, S. H.; Jafari, S., E-mail: sjafari@guilan.ac.ir; Raghavi, A.

    2016-05-15

    Significant progress has been made employing plasmas in the free-electron lasers (FELs) interaction region. In this regard, we study the output power and saturation length of the plasma whistler wave-pumped FEL in a magnetized plasma channel. The small wavelength of the whistler wave (in sub-μm range) in plasma allows obtaining higher radiation frequency than conventional wiggler FELs. This configuration has a higher tunability by adjusting the plasma density relative to the conventional ones. A set of coupled nonlinear differential equations is employed which governs on the self-consistent evolution of an electromagnetic wave. The electron bunching process of the whistler-pumped FELmore » has been investigated numerically. The result reveals that for a long wiggler length, the bunching factor can appreciably change as the electron beam propagates through the wiggler. The effects of plasma frequency (or plasma density) and cyclotron frequency on the output power and saturation length have been studied. Simulation results indicate that with increasing the plasma frequency, the power increases and the saturation length decreases. In addition, when density of background plasma is higher than the electron beam density (i.e., for a dense plasma channel), the plasma effects are more pronounced and the FEL-power is significantly high. It is also found that with increasing the strength of the external magnetic field frequency, the power decreases and the saturation length increases, noticeably.« less

  7. Lipid-lowering effects of TAK-475, a squalene synthase inhibitor, in animal models of familial hypercholesterolemia.

    PubMed

    Amano, Yuichiro; Nishimoto, Tomoyuki; Tozawa, Ryu ichi; Ishikawa, Eiichiro; Imura, Yoshimi; Sugiyama, Yasuo

    2003-04-11

    The lipid-lowering effects of 1-[2-[(3R,5S)-1-(3-acetoxy-2,2-dimethylpropyl)-7-chloro-1,2,3,5-tetrahydro-2-oxo-5-(2,3-dimethoxyphenyl)-4,1-benzoxazepine-3-yl] acetyl] piperidin-4-acetic acid (TAK-475), a novel squalene synthase inhibitor, were examined in two models of familial hypercholesterolemia, low-density lipoprotein (LDL) receptor knockout mice and Watanabe heritable hyperlipidemic (WHHL) rabbits. Two weeks of treatment with TAK-475 in a diet admixture (0.02% and 0.07%; approximately 30 and 110 mg/kg/day, respectively) significantly lowered plasma non-high-density lipoprotein (HDL) cholesterol levels by 19% and 41%, respectively, in homozygous LDL receptor knockout mice. The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, simvastatin and atorvastatin (in 0.02% and 0.07% admixtures), also reduced plasma levels of non-HDL cholesterol. In homozygous WHHL rabbits, 4 weeks of treatment with TAK-475 (0.27%; approximately 100 mg/kg/day) lowered plasma total cholesterol, triglyceride and phospholipid levels by 17%, 52% and 26%, respectively. In Triton WR-1339-treated rabbits, TAK-475 inhibited to the same extent the rate of secretion from the liver of the cholesterol, triglyceride and phospholipid components of very-low-density lipoprotein (VLDL). These results suggest that the lipid-lowering effects of TAK-475 in WHHL rabbits are based partially on the inhibition of secretion of VLDL from the liver. TAK-475 had no effect on plasma aspartate aminotransferase and alanine aminotransferase activities. Thus, the squalene synthase inhibitor TAK-475 revealed lipid-lowering effects in both LDL receptor knockout mice and WHHL rabbits.

  8. Distribution and Kinetics of Lipoprotein-Bound Lipoteichoic Acid

    PubMed Central

    Levels, Johannes H. M.; Abraham, Philip R.; van Barreveld, Erik P.; Meijers, Joost C. M.; van Deventer, Sander J. H.

    2003-01-01

    Lipoteichoic acid (LTA), a major cell wall component of gram-positive bacteria, is an amphipathic anionic glycolipid with structural similarities to lipopolysaccharide (LPS) from gram-negative bacteria. LTA has been implicated as one of the primary immunostimulatory components that may trigger the systemic inflammatory response syndrome. Plasma lipoproteins have been shown to sequester LPS, which results in attenuation of the host response to infection, but little is known about the LTA binding characteristics of plasma lipid particles. In this study, we have examined the LTA binding capacities and association kinetics of the major lipoprotein classes under simulated physiological conditions in human whole blood (ex vivo) by using biologically active, fluorescently labeled LTA and high-performance gel permeation chromatography. The average distribution of an LTA preparation from Staphylococcus aureus in whole blood from 10 human volunteers revealed that >95% of the LTA was associated with total plasma lipoproteins in the following proportions: high-density lipoprotein (HDL), 68% ± 10%; low-density lipoprotein (LDL), 28% ± 8%; and very low density lipoprotein (VLDL), 4% ± 5%. The saturation capacity of lipoproteins for LTA was in excess of 150 μg/ml. The LTA distribution was temperature dependent, with an optimal binding between 22 and 37°C. The binding of LTA by lipoproteins was essentially complete within 10 min and was followed by a subsequent redistribution from HDL and VLDL to LDL. We conclude that HDL has the highest binding capacity for LTA and propose that the loading and redistribution of LTA among plasma lipoproteins is a specific process that closely resembles that previously described for LPS (J. H. M. Levels, P. R. Abraham, A. van den Ende, and S. J. H. van Deventer, Infect. Immun. 68:2821-2828, 2001). PMID:12761109

  9. A review of low density porous materials used in laser plasma experiments

    NASA Astrophysics Data System (ADS)

    Nagai, Keiji; Musgrave, Christopher S. A.; Nazarov, Wigen

    2018-03-01

    This review describes and categorizes the synthesis and properties of low density porous materials, which are commonly referred to as foams and are utilized for laser plasma experiments. By focusing a high-power laser on a small target composed of these materials, high energy and density states can be produced. In the past decade or so, various new target fabrication techniques have been developed by many laboratories that use high energy lasers and consequently, many publications and reviews followed these developments. However, the emphasis so far has been on targets that did not utilize low density porous materials. This review therefore, attempts to redress this balance and endeavors to review low density materials used in laser plasma experiments in recent years. The emphasis of this review will be on aspects of low density materials that are of relevance to high energy laser plasma experiments. Aspects of low density materials such as densities, elemental compositions, macroscopic structures, nanostructures, and characterization of these materials will be covered. Also, there will be a brief mention of how these aspects affect the results in laser plasma experiments and the constrictions that these requirements put on the fabrication of low density materials relevant to this field. This review is written from the chemists' point of view to aid physicists and the new comers to this field.

  10. Implementation of the new multichannel X-mode edge density profile reflectometer for the ICRF antenna on ASDEX Upgrade

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aguiam, D. E., E-mail: daguiam@ipfn.tecnico.ulisboa.pt; Silva, A.; Carvalho, P. J.

    A new multichannel frequency modulated continuous-wave reflectometry diagnostic has been successfully installed and commissioned on ASDEX Upgrade to measure the plasma edge electron density profile evolution in front of the Ion Cyclotron Range of Frequencies (ICRF) antenna. The design of the new three-strap ICRF antenna integrates ten pairs (sending and receiving) of microwave reflectometry antennas. The multichannel reflectometer can use three of these to measure the edge electron density profiles up to 2 × 10{sup 19} m{sup −3}, at different poloidal locations, allowing the direct study of the local plasma layers in front of the ICRF antenna. ICRF power coupling,more » operational effects, and poloidal variations of the plasma density profile can be consistently studied for the first time. In this work the diagnostic hardware architecture is described and the obtained density profile measurements were used to track outer radial plasma position and plasma shape.« less

  11. A novel male contraceptive pill-patch combination: oral desogestrel and transdermal testosterone in the suppression of spermatogenesis in normal men.

    PubMed

    Hair, W M; Kitteridge, K; O'Connor, D B; Wu, F C

    2001-11-01

    This study investigated the effect of transdermal T and oral desogestrel on the reproductive axis of healthy men. Twenty-three men were randomized to 1 of 3 treatment groups and received a daily transdermal T patch plus oral desogestrel at a dose of 75, 150, or 300 microg/d for 24 wk. Baseline blood and semen samples were obtained and then every 4 wk thereafter for 32 wk. The outcome measures were sperm density and plasma levels of FSH, LH, total and free T. The results show a dose-dependent suppression of spermatogenesis and gonadotropins. Seven of the 17 subjects became azoospermic. Desogestrel (300 microg daily) in combination with 5 mg daily transdermal T was the most effective (57% azoospermic), whereas a dose of 75 microg was ineffective (0% azoospermic). Total and free plasma T were reduced by approximately 30%. High density lipoprotein cholesterol was significantly reduced. No serious side-effects were encountered. We conclude that daily self-administered desogestrel with transdermal T is capable of suppressing the male reproductive axis, although the efficacy was less marked and less consistent than injectable regimens. The lower efficacy is likely to be due to failure of the transdermal T system to maintain circulating T levels consistently in the required range.

  12. Intercorrelations among plasma high density lipoprotein, obesity and triglycerides in a normal population.

    PubMed

    Albrink, M J; Krauss, R M; Lindgrem, F T; von der Groeben, J; Pan, S; Wood, P D

    1980-09-01

    The interrelationships among fatness measures, plasma triglycerides and high density lipoproteins (HDL) were examined in 131 normal adult subjects: 38 men aged 27-46, 40 men aged 47-66, 29 women aged 27-46 and 24 women aged 47-66. None of the women were taking estrogens or oral contraceptive medication. The HDL concentration was subdivided into HDL2b, HDL2a and HDL3 by a computerized fitting of the total schlieren pattern to reference schlieren patterns. Anthropometric measures employed included skinfolds at 3 sites. 2 weight/height indices and 2 girth measurements. A high correlation was found among the various fatness measures. These measures were negatively correlated with total HDL, reflecting the negative correlation between fatness measures and HDL2 (as the sum of HDL2a and 2b). Fatness measures showed no relationship to HDL3. There was also an inverse correlation between triglyceride concentration and HDL2. No particular fatness measure was better than any other for demonstrating the inverse correlation with HDL but multiple correlations using all of the measures of obesity improved the correlations. Partial correlations controlling for fatness did not reduce any of the significant correlations between triglycerides and HDL2 to insignificance. The weak correlation between fatness and triglycerides was reduced to insignificance when controlled for HDL2.

  13. The transition mechanisms of the E to H mode and the H to E mode in an inductively coupled argon-mercury mixture discharge

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Xiao; Yu, Peng-Cheng; Liu, Yu

    2015-10-15

    In our experiment, the transition points between the two operational modes of capacitive coupling (E mode) and inductive coupling (H mode) were investigated at a wide range of mercury vapor pressures in an inductively coupled plasma, varying with the input radio-frequency powers and the total filling pressures (10 Pa–30 Pa). The electron temperatures were calculated versus with the mercury vapor pressures for different values of the total filling pressures. The transition power points and electron density also were measured in this study. It is shown that the transition powers, whether the E to H mode transition or the H to E modemore » transition, are lower than that of the argon discharge, and these powers almost increase with the mercury vapor pressure rising. However, the transition electron density follows an inverse relationship with the mercury vapor pressures compared with the transition powers. In addition, at the lower pressures and higher mercury vapor pressures, an inverse hysteresis was observed clearly, which did not appear in the argon gas plasma. We suggest that all these results are attributed to the electron-neutral collision frequency changed with the additional mercury vapor pressures.« less

  14. Thomson-scattering measurements in the collective and noncollective regimes in laser produced plasmas (invited).

    PubMed

    Ross, J S; Glenzer, S H; Palastro, J P; Pollock, B B; Price, D; Tynan, G R; Froula, D H

    2010-10-01

    We present simultaneous Thomson-scattering measurements of light scattered from ion-acoustic and electron-plasma fluctuations in a N(2) gas jet plasma. By varying the plasma density from 1.5×10(18) to 4.0×10(19) cm(-3) and the temperature from 100 to 600 eV, we observe the transition from the collective regime to the noncollective regime in the high-frequency Thomson-scattering spectrum. These measurements allow an accurate local measurement of fundamental plasma parameters: electron temperature, density, and ion temperature. Furthermore, experiments performed in the high densities typically found in laser produced plasmas result in scattering from electrons moving near the phase velocity of the relativistic plasma waves. Therefore, it is shown that even at low temperatures relativistic corrections to the scattered power must be included.

  15. Effects of diets containing high or low amounts of stearic acid on plasma lipoprotein fractions and fecal fatty acid excretion of men.

    PubMed

    Dougherty, R M; Allman, M A; Iacono, J M

    1995-05-01

    Ten middle-aged males participated in a crossover study to determine the cholesterolemic effect of high amounts of stearic acid in a natural diet. They consumed a 20-d stabilization diet followed by two 40-d intervention diets containing either 1.5% of energy as stearic (18:0) acid and 7.3% of energy as palmitic (16:0) acid (low stearate: LS) or 2.4% of energy as 16:0 and 7.3% of energy as 18:0 (high stearate: HS). The experimental diets also contained approximately 10% of energy each as saturated and monounsaturated fatty acids and 7.2-8% of energy as polyunsaturated fatty acids. The primary source of 18:0 in the HS diet was sheanut oil (commercially referred to as shea butter) and palm oil and butter in the LS diet. Plasma total, low-density-lipoprotein, and high-density-lipoprotein cholesterol were significantly lower with the HS than with the LS diet. Total fecal fatty acid excretion was higher throughout the HS period. Apparent digestibility of the major dietary fatty acids showed that all of the selected fatty acids, except 18:0, were > or = 95% absorbed. These data demonstrate that feeding diets containing about two times the usual amount of stearic acid consumed in the United States, contributed to an increase in plasma lipoprotein concentrations at 40 d from an earlier decrease at 20 d. The time required to achieve stable cholesterol concentrations appears to vary depending on the kind of saturated fatty acids present in the diet.

  16. Application and Analysis of the Isoelectronic Line Ratio Temperature Diagnostic in a Planar Ablating-Plasma Experiment at the National Ignition Facility

    NASA Astrophysics Data System (ADS)

    Epstein, R.; Rosenberg, M. J.; Solodov, A. A.; Myatt, J. F.; Regan, S. P.; Seka, W.; Hohenberger, M.; Barrios, M. A.; Moody, J. D.

    2015-11-01

    The Mn/Co isoelectronic emission-line ratio from a microdot source in planar CH foil targets was measured to infer the electron temperature (Te) in the ablating plasma during two-plasmon-decay experiments at the National Ignition Facility (NIF). We examine the systematic uncertainty in the Te estimate based on the temperature and density sensitivities of the line ratio in conjunction with plausible density constraints, and its contribution to the total Te estimate uncertainty. The potential advantages of alternative microdot elements (e.g., Ti/Cr and Sc/V) are considered. The microdot mass was selected to provide ample line strength while minimizing the effect of self-absorption on the line emission, which is of particular concern, given the narrow linewidths of mid- Z emitters at subcritical electron densities. Atomic line-formation theory and detailed atomic-radiative simulations show that the straight forward interpretation of the isoelectronic ratio solely in terms of its temperature independence remains valid with lines of moderate optical thickness (up to ~ 10) at line center. This material is based upon work supported by the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944.

  17. The influence of anode position and structure on cusped field thruster

    NASA Astrophysics Data System (ADS)

    Niu, Xiang; Liu, Hui; Yang, Chiyu; Jiang, Wenjia; Yu, Daren; Ning, Zhongxi

    2018-04-01

    A cusped field thruster is a kind of electric propulsion device using multi-stage cusped fields to realize plasma discharges and produce thrust. A previous study showed that plasma discharges in this thruster are non-uniform. In this work, a multi-annulus anode is used to measure the radial distribution of anode current density at different anode positions. The experimental results reveal that some electrons may reach the anode along the axis after they accelerate from the final cusp regardless of the anode positions. To further validate this idea and find out the mechanism of this central path along the axis, the central part of the anode is replaced with ceramics. This results in an increase in the total current with larger contributions at larger radii. The current oscillations also get larger. This brief letter is helpful to further understand the movement of electrons in cusped field thrusters and provide guidance on reducing the non-uniform degree of current density.

  18. Volume Measurements of Laser-generated Pits for In Situ Geochronology using KArLE (Potassium-Argon Laser Experiment)

    NASA Technical Reports Server (NTRS)

    French, R. A.; Cohen, B. A.; Miller, J. S.

    2014-01-01

    The Potassium-Argon Laser Experiment( KArLE), is composed of two main instruments: a spectrometer as part of the Laser-Induced Breakdown Spectroscopy (LIBS) method and a Mass Spectrometer (MS). The LIBS laser ablates a sample and creates a plasma cloud, generating a pit in the sample. The LIBS plasma is measured for K abundance in weight percent and the released gas is measured using the MS, which calculates Ar abundance in mols. To relate the K and Ar measurements, total mass of the ablated sample is needed but can be difficult to directly measure. Instead, density and volume are used to calculate mass, where density is calculated based on the elemental composition of the rock (from the emission spectrum) and volume is determined by pit morphology. This study aims to reduce the uncertainty for KArLE by analyzing pit volume relationships in several analog materials and comparing methods of pit volume measurements and their associated uncertainties.

  19. CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL.

    PubMed

    Bartuzi, Paulina; Billadeau, Daniel D; Favier, Robert; Rong, Shunxing; Dekker, Daphne; Fedoseienko, Alina; Fieten, Hille; Wijers, Melinde; Levels, Johannes H; Huijkman, Nicolette; Kloosterhuis, Niels; van der Molen, Henk; Brufau, Gemma; Groen, Albert K; Elliott, Alison M; Kuivenhoven, Jan Albert; Plecko, Barbara; Grangl, Gernot; McGaughran, Julie; Horton, Jay D; Burstein, Ezra; Hofker, Marten H; van de Sluis, Bart

    2016-03-11

    The low-density lipoprotein receptor (LDLR) plays a pivotal role in clearing atherogenic circulating low-density lipoprotein (LDL) cholesterol. Here we show that the COMMD/CCDC22/CCDC93 (CCC) and the Wiskott-Aldrich syndrome protein and SCAR homologue (WASH) complexes are both crucial for endosomal sorting of LDLR and for its function. We find that patients with X-linked intellectual disability caused by mutations in CCDC22 are hypercholesterolaemic, and that COMMD1-deficient dogs and liver-specific Commd1 knockout mice have elevated plasma LDL cholesterol levels. Furthermore, Commd1 depletion results in mislocalization of LDLR, accompanied by decreased LDL uptake. Increased total plasma cholesterol levels are also seen in hepatic COMMD9-deficient mice. Inactivation of the CCC-associated WASH complex causes LDLR mislocalization, increased lysosomal degradation of LDLR and impaired LDL uptake. Furthermore, a mutation in the WASH component KIAA0196 (strumpellin) is associated with hypercholesterolaemia in humans. Altogether, this study provides valuable insights into the mechanisms regulating cholesterol homeostasis and LDLR trafficking.

  20. Early Evolution of Comet 67P Studied with the RPC-LAP onboard Rosetta

    NASA Astrophysics Data System (ADS)

    Miloch, W. J.; Yang, L.; Paulsson, J. J.; Wedlund, C. S.; Odelstad, E.; Edberg, N. J. T.; Koenders, C.; Eriksson, A.

    2016-12-01

    In-situ measurements within the Rosetta mission allow for studies of the cometary environment at different stages of cometary evolution. The Rosetta Plasma Consortium (RPC) is a set of five instruments on board the spacecraft that specialise in the measurements of plasma environment of comet 67P. One of the instruments is RPC-LAP, which consists of two Langmuir Probes and can measure the density, temperature, and flow speed of the plasma in the vicinity of the comet. At the early stage of the Rosetta mission, when the spacecraft is far from the nucleus of comet 67P, the ion part of the current-voltage characteristics of RPC-LAP1 is dominated by the photoemission current, which surpasses the currents from the dilute solar wind plasma. As Rosetta starts orbiting around the nucleus in September 2014, LAP1 picks up signatures of local plasma density enhancements corresponding to variations of water-group ions observed in the vicinity of the comet. With the help of current-voltage characteristics and the spacecraft potential, we identify and characterise in space and time the entering of this coma-dominated, high-density plasma region. This high-density region is observed at the northern hemisphere of the comet during early activity. The transition manifests as a steep gradient in the density with respect to the distance to the comet nucleus. We discuss these RPC-LAP results together with the corresponding measurements by other instruments to provide a comprehensive picture of the transition. We show that the early cometary plasma can be seen as composed of two distinct regions: an outer region characterised by solar wind plasma and small quantities of pickup ions, and an inner region with enhanced plasma densities.

  1. Density Variations in the Earth's Magnetospheric Cusps

    NASA Technical Reports Server (NTRS)

    Walsh, B. M.; Niehof, J.; Collier, M. R.; Welling, D. T.; Sibeck, D. G.; Mozer, F. S.; Fritz, T. A.; Kuntz, K. D.

    2016-01-01

    Seven years of measurements from the Polar spacecraft are surveyed to monitor the variations of plasma density within the magnetospheric cusps. The spacecraft's orbital precession from 1998 through 2005 allows for coverage of both the northern and southern cusps from low altitude out to the magnetopause. In the mid- and high- altitude cusps, plasma density scales well with the solar wind density (n(sub cusp)/n(sub sw) approximately 0.8). This trend is fairly steady for radial distances greater then 4 R(sub E). At low altitudes (r less than 4R(sub E)) the density increases with decreasing altitude and even exceeds the solar wind density due to contributions from the ionosphere. The density of high charge state oxygen (O(greater +2) also displays a positive trend with solar wind density within the cusp. A multifluid simulation with the Block-Adaptive-Tree Solar Wind Roe-Type Upwind Scheme MHD model was run to monitor the relative contributions of the ionosphere and solar wind plasma within the cusp. The simulation provides similar results to the statistical measurements from Polar and confirms the presence of ionospheric plasma at low altitudes.

  2. A comparative study of radiofrequency antennas for Helicon plasma sources

    NASA Astrophysics Data System (ADS)

    Melazzi, D.; Lancellotti, V.

    2015-04-01

    Since Helicon plasma sources can efficiently couple power and generate high-density plasma, they have received interest also as spacecraft propulsive devices, among other applications. In order to maximize the power deposited into the plasma, it is necessary to assess the performance of the radiofrequency (RF) antenna that drives the discharge, as typical plasma parameters (e.g. the density) are varied. For this reason, we have conducted a comparative analysis of three Helicon sources which feature different RF antennas, namely, the single-loop, the Nagoya type-III and the fractional helix. These antennas are compared in terms of input impedance and induced current density; in particular, the real part of the impedance constitutes a measure of the antenna ability to couple power into the plasma. The results presented in this work have been obtained through a full-wave approach which (being hinged on the numerical solution of a system of integral equations) allows computing the antenna current and impedance self-consistently. Our findings indicate that certain combinations of plasma parameters can indeed maximize the real part of the input impedance and, thus, the deposited power, and that one of the three antennas analyzed performs best for a given plasma. Furthermore, unlike other strategies which rely on approximate antenna models, our approach enables us to reveal that the antenna current density is not spatially uniform, and that a correlation exists between the plasma parameters and the spatial distribution of the current density.

  3. Placental malaria and modulation of immune and hormonal responses in Cameroonian women.

    PubMed

    Megnekou, Rosette; Tenou, Sandrine; Bigoga, Jude D; Djontu, Jean Claude; Medou, Fabrice Mbah; Lissom, Abel

    2015-07-01

    Adverse pregnancy outcomes place the lives of mother and new born babies in jeopardy, especially in Sub Saharan Africa. Although a well-balanced network of the pregnancy-associated hormones and lipid fractions is necessary for healthy pregnancy, the profiles of some of these biomarkers alongside those of some cytokines in relation to placental malaria (PM) and poor pregnancy outcomes are unknown. Therefore between 2013 and 2014, paired peripheral and placental blood samples were collected from 135 Cameroonian women at delivery. Parasitaemia was determined microscopically and haemoglobin levels using Coulter counter. Plasma levels of cytokines (IFN-γ, IL-1β and IL-7) and pregnancy-associated hormones (17β oestradiol and progesterone) were measured by ELISA and the levels of lipid fractions: total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG) determined by Colorimetric enzymatic methods. Parasitaemia was inversely related to parity, haemoglobin levels and birth weight (P≤0.019). While the levels of IFN-γ and cholesterol (total, HDL and LDL) were higher in peripheral plasma, those of IL-1β, 17β oestradiol, progesterone and triglyceride were higher in placental blood (P<0.001). Absence of PM was significantly associated with high plasma levels of IFN-γ, IL-7 and HDL-C and low plasma levels of 17β oestradiol and TG. Moreover, IL-7 levels correlated positively and significantly with haemoglobin levels and with both peripheral and placental levels of progesterone. Baby birth weight increased with plasma levels of progesterone and HDL-C. Levels of IFN-γ correlated positively and significantly with HDL-C, but negatively with LDL-C; thus, might prevent pregnant women from atherogenic risk. Study of the inter-relationship between hormones, cytokines and lipids revealed that the association between IL-7 and progesterone and/or some lipid fractions followed inverse trends from that of IFN-γ. These results suggest that in PM, IFN-γ and IL-7 might protect against poor pregnancy outcomes, which decrease plasma levels of progesterone, maternal haemoglobin and HDL-C, leading to low birth weight. However, these cytokines may act differently with regards to progesterone and some lipid fractions. PM may also lower plasma levels of HDL-C and increase that of TG which is the most important risk factor for cardiovascular disorders and consequently poor pregnancy outcomes. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Dietary Choline Intake Is Directly Associated with Bone Mineral Density in the Hordaland Health Study.

    PubMed

    Øyen, Jannike; Gjesdal, Clara Gram; Karlsson, Therese; Svingen, Gard Ft; Tell, Grethe S; Strand, Elin; Drevon, Christian A; Vinknes, Kathrine J; Meyer, Klaus; Ueland, Per Magne; Nygård, Ottar

    2017-04-01

    Background: Choline is an important nutrient either obtained from a variety of foods or synthesized endogenously, and it is the precursor of betaine. We previously reported positive associations between plasma free choline and bone mineral density (BMD). Animal studies suggest an impact of dietary choline on bone metabolism, but the role of dietary intake of choline and betaine for human bone health is unknown. Objectives: The main aims were to examine the associations of dietary choline, choline species, and betaine with BMD and to study the relations between dietary and plasma free choline and betaine. Methods: Study subjects were participants in the Hordaland Health Study, including 2649 women and 1983 men (aged 46-49 or 71-74 y). BMD was measured by dual-energy X-ray absorptiometry, and dietary intake was obtained by using a validated 169-item food-frequency questionnaire. Risk associations were assessed by logistic regression and correlations by ρ (Spearman's bivariate rank order correlation). Results: Subjects in the lowest compared with the highest tertile of dietary total choline, free choline, glycerophosphocholine, phosphocholine, phosphatidylcholine, and sphingomyelin had a higher risk of low-femoral neck BMD, defined as the lowest BMD quintile. Particularly strong associations were found among middle-aged men for intake of free choline (OR: 1.83; 95% CI: 1.24, 2.69; P = 0.002) and glycerophosphocholine (OR: 2.13; 95% CI: 1.43, 3.16; P < 0.001) and among elderly women for total choline (OR: 1.96; 95% CI: 1.33, 2.88; P = 0.001) and phosphatidylcholine (OR: 1.94; 95% CI: 1.33, 2.84: P = 0.001) intake. No significant associations were observed between dietary betaine and BMD. Dietary total choline, free choline, glycerophosphocholine, phosphatidylcholine, and sphingomyelin correlated weakly with plasma free choline (ρ: 0.07, 0.05, 0.07, 0.07, and 0.05, respectively; P < 0.01). Dietary betaine correlated with plasma betaine (ρ: 0.23; P < 0.001). Conclusion: Dietary choline was positively associated with BMD in middle-aged and elderly participants. © 2017 American Society for Nutrition.

  5. Analysis by oxygen atom number density measurement of high-speed hydrophilic treatment of polyimide using atmospheric pressure microwave plasma

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ono, S.

    2015-03-30

    This paper describes the fundamental experimental data of the plasma surface modification of the polyimide using atmospheric pressure microwave plasma source. The experimental results were discussed from the point of view of the radical’s behavior, which significantly affects the modification mechanism. The purpose of the study is to examine how the value of the oxygen atom density will affect the hydrophilic treatment in the upstream region of the plasma where gas temperature is very high. The surface modification experiments were performed by setting the polyimide film sample in the downstream region of the plasma. The degree of the modification wasmore » measured by a water contact angle measurement. The water contact angle decreased less than 30 degrees within 1 second treatment time in the upstream region. Very high speed modification was observed. The reason of this high speed modification seems that the high density radical which contributes the surface modification exist in the upstream region of the plasma. This tendency is supposed to the measured relatively high electron density (~10{sup 15}cm{sup −3}) at the center of the plasma. We used the electric heating catalytic probe method for oxygen radical measurement. An absolute value of oxygen radical density was determined by catalytic probe measurement and the results show that ~10{sup 15}cm{sup −3} of the oxygen radical density in the upstream region and decreases toward downstream region. The experimental results of the relation of the oxygen radical density and hydrophilic modification of polyimide was discussed.« less

  6. Radiation reabsorption in a laser-produced plasma

    NASA Astrophysics Data System (ADS)

    Brunner, W.; John, R. W.; Paul, H.; Steudel, H.

    1988-11-01

    Taking into account the emission and absorption of resonance radiation in a recombining laser-produced plasma of intermediate density, the system of rate equations for the population densities coupled with the radiative transfer equation is approximately treated. In the case of spatially varying absorption, an approximate form of the rate equation determining the population density of the upper resonance level is derived. By applying this relation to an axially symmetric plasma, a simple formula that describes the effect of radiation reabsorption on the spatial behavior of the population density is obtained.

  7. Self-consistent discharge growing model of helicon plasma

    NASA Astrophysics Data System (ADS)

    Isayama, Shogo; Hada, Tohru; Shinohara, Shunjiro; Tanikawa, Takao

    2015-11-01

    Helicon plasma is a high-density and low-temperature plasma generated by the electromagnetic (Helicon) wave excited in the plasma. It is thought to be useful for various applications including electric thrusters. Physics of helicon plasma production involves such fundamental processes as the wave propagation (dispersion relation), collisional and non-collisional wave damping, plasma heating, ionization/recombination of neutral particles, and modification of the dispersion relation by newly ionized plasma. There remain a number of unsolved physical issues such as, how the Helicon and the TG modes influence the plasma density, electron temperature and their spatial profiles. While the Helicon mode is absorbed in the bulk plasma, the TG mode is mostly absorbed near the edge of the plasma. The local power deposition in the helicon plasma is mostly balanced by collisional loss. This local power balance can give rise to the inhomogeneous electron temperature profile that leads to time evolution of density profile and dispersion relation. In our study, we construct a self-consistent model of the discharge evolution that includes the wave excitation, electron heat transfer, and diffusion of charged particles.

  8. Plasma waves associated with the first AMPTE magnetotail barium release

    NASA Technical Reports Server (NTRS)

    Gurnett, D. A.; Anderson, R. R.; Bernhardt, P. A.; Luehr, H.; Haerendel, G.

    1986-01-01

    Plasma waves observed during the March 21, 1985, AMPTE magnetotail barium release are described. Electron plasma oscillations provided local measurements of the plasma density during both the expansion and decay phases. Immediately after the explosion, the electron density reached a peak of about 400,000/cu cm, and then started decreasing approximately as t to the -2.4 as the cloud expanded. About 6 minutes after the explosion, the electron density suddenly began to increase, reached a secondary peak of about 240/cu cm, and then slowly decayed down to the preevent level over a period of about 15 minutes. The density increase is believed to be caused by the collapse of the ion cloud into the diamagnetic cavity created by the initial expansion. The plasma wave intensities observed during the entire event were quite low. In the diamagnetic cavity, electrostatic emissions were observed near the barium ion plasma frequency, and in another band at lower frequencies. A broadband burst of electrostatic noise was also observed at the boundary of the diamagnetic cavity. Except for electron plasma oscillations, no significant wave activity was observed outside of the diamagnetic cavity.

  9. Core Radial Electric Field and Transport in Wendelstein 7-X Plasmas

    NASA Astrophysics Data System (ADS)

    Pablant, Novimir

    2016-10-01

    Results from the investigation of core transport and the role of the radial electric field profile (Er) in the first operational phase of the Wendelstein 7-X (W7-X) stellarator are presented. In stellarator plasmas, the details of the Er profile are expected to have a strong effect on both the particle and heat fluxes. Neoclassical particle fluxes are not intrinsically ambipolar, which leads to the formation of a radial electric field that enforces ambipolarity. The radial electric field is closely related to the perpendicular plasma flow (u⊥) through the force balance equation. This allows the radial electric field to be inferred from measurements of the perpendicular flow velocity from the x-ray imaging crystal spectrometer (XICS) and correlation reflectometry diagnostics. Large changes in the perpendicular rotation, on the order of Δu⊥ 5km /s (ΔEr 12kV / m), have been observed within a set of experiments where the heating power was stepped down from 2 MW to 0.6 MW . These experiments are examined in detail to explore the relationship between, heating power, response of the temperature and density profiles and the response of the radial electric field. Estimations of the core transport are based on power balance and utilize electron temperature (Te) profiles from the ECE and Thomson scattering, electron density profiles (ne) from interferometry and Thomson scattering, ion temperature (Ti) profiles from XICS, along with measurements of the total stored energy and radiated power. Also described are a set core impurity confinement experiments and results. Impurity confinement has been investigated through the injection of trace amount of argon impurity gas at the plasma edge in conjunction with measurements of the density of various ionization states of argon from the XICS and High Efficiency eXtreme-UV Overview Spectrometer (HEXOS) diagnostics. Finally the inferred Er and heat flux profiles are compared to initial neoclassical calculations using measured plasma profiles. On behalf of the W7-X Team.

  10. Fluid simulation of the bias effect in inductive/capacitive discharges

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Yu-Ru; Research Group PLASMANT, Department of Chemistry, University of Antwerp, Universiteitsplein 1, Wilrijk, BE-2610 Antwerp; Gao, Fei

    Computer simulations are performed for an argon inductively coupled plasma (ICP) with a capacitive radio-frequency bias power, to investigate the bias effect on the discharge mode transition and on the plasma characteristics at various ICP currents, bias voltages, and bias frequencies. When the bias frequency is fixed at 13.56 MHz and the ICP current is low, e.g., 6 A, the spatiotemporal averaged plasma density increases monotonically with bias voltage, and the bias effect is already prominent at a bias voltage of 90 V. The maximum of the ionization rate moves toward the bottom electrode, which indicates clearly the discharge mode transition in inductive/capacitivemore » discharges. At higher ICP currents, i.e., 11 and 13 A, the plasma density decreases first and then increases with bias voltage, due to the competing mechanisms between the ion acceleration power dissipation and the capacitive power deposition. At 11 A, the bias effect is still important, but it is noticeable only at higher bias voltages. At 13 A, the ionization rate is characterized by a maximum at the reactor center near the dielectric window at all selected bias voltages, which indicates that the ICP power, instead of the bias power, plays a dominant role under this condition, and no mode transition is observed. Indeed, the ratio of the bias power to the total power is lower than 0.4 over a wide range of bias voltages, i.e., 0–300 V. Besides the effect of ICP current, also the effect of various bias frequencies is investigated. It is found that the modulation of the bias power to the spatiotemporal distributions of the ionization rate at 2 MHz is strikingly different from the behavior observed at higher bias frequencies. Furthermore, the minimum of the plasma density appears at different bias voltages, i.e., 120 V at 2 MHz and 90 V at 27.12 MHz.« less

  11. Study of Volumetrically Heated Ultra-High Energy Density Plasmas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rocca, Jorge J.

    2016-10-27

    Heating dense matter to millions of degrees is important for applications, but requires complex and expensive methods. The major goal of the project was to demonstrate using a compact laser the creation of a new ultra-high energy density plasma regime characterized by simultaneous extremely high temperature and high density, and to study it combining experimental measurements and advanced simulations. We have demonstrated that trapping of intense femtosecond laser pulses deep within ordered nanowire arrays can heat near solid density matter into a new ultra hot plasma regime. Extreme electron densities, and temperatures of several tens of million degrees were achievedmore » using laser pulses of only 0.5 J energy from a compact laser. Our x-ray spectra and simulations showed that extremely highly ionized plasma volumes several micrometers in depth are generated by irradiation of gold and Nickel nanowire arrays with femtosecond laser pulses of relativistic intensities. We obtained extraordinarily high degrees of ionization (e.g. we peeled 52 electrons from gold atoms, and up to 26 electrons from nickel atoms). In the process we generated Gigabar pressures only exceeded in the central hot spot of highly compressed thermonuclear fusion plasmas.. The plasma created after the dissolved wires expand, collide, and thermalize, is computed to have a thermal energy density of 0.3 GJ cm -3 and a pressure of 1-2 Gigabar. These are pressures only exceeded in highly compressed thermonuclear fusion plasmas. Scaling these results to higher laser intensities promises to create plasmas with temperatures and pressures exceeding those in the center of the sun.« less

  12. Flux of OH and O radicals onto a surface by an atmospheric-pressure helium plasma jet measured by laser-induced fluorescence

    NASA Astrophysics Data System (ADS)

    Yonemori, Seiya; Ono, Ryo

    2014-03-01

    The atmospheric-pressure helium plasma jet is of emerging interest as a cutting-edge biomedical device for cancer treatment, wound healing and sterilization. Reactive oxygen species such as OH and O radicals are considered to be major factors in the application of biological plasma. In this study, density distribution, temporal behaviour and flux of OH and O radicals on a surface are measured using laser-induced fluorescence. A helium plasma jet is generated by applying pulsed high voltage of 8 kV with 10 kHz using a quartz tube with an inner diameter of 4 mm. To evaluate the relation between the surface condition and active species production, three surfaces are used: dry, wet and rat skin. When the helium flow rate is 1.5 l min-1, radial distribution of OH density on the rat skin surface shows a maximum density of 1.2 × 1013 cm-3 at the centre of the plasma-mediated area, while O atom density shows a maximum of 1.0 × 1015 cm-3 at 2.0 mm radius from the centre of the plasma-mediated area. Their densities in the effluent of the plasma jet are almost constant during the intervals of the discharge pulses because their lifetimes are longer than the pulse interval. Their density distribution depends on the helium flow rate and the surface humidity. With these results, OH and O production mechanisms in the plasma jet and their flux onto the surface are discussed.

  13. Sheared-flow induced confinement transition in a linear magnetized plasma

    NASA Astrophysics Data System (ADS)

    Zhou, S.; Heidbrink, W. W.; Boehmer, H.; McWilliams, R.; Carter, T. A.; Vincena, S.; Friedman, B.; Schaffner, D.

    2012-01-01

    A magnetized plasma cylinder (12 cm in diameter) is induced by an annular shape obstacle at the Large Plasma Device [W. Gekelman, H. Pfister, Z. Lucky, J. Bamber, D. Leneman, and J. Maggs, Rev. Sci. Instrum. 62, 2875 (1991)]. Sheared azimuthal flow is driven at the edge of the plasma cylinder through edge biasing. Strong fluctuations of density and potential (δn /n~eδφ/kTe~0.5) are observed at the plasma edge, accompanied by a large density gradient (Ln=|∇lnn |-1~2cm) and shearing rate (γ ~300kHz). Edge turbulence and cross-field transport are modified by changing the bias voltage (Vbias) on the obstacle and the axial magnetic field (Bz) strength. In cases with low Vbias and large Bz, improved plasma confinement is observed, along with steeper edge density gradients. The radially sheared flow induced by E ×B drift dramatically changes the cross-phase between density and potential fluctuations, which causes the wave-induced particle flux to reverse its direction across the shear layer. In cases with higher bias voltage or smaller Bz, large radial transport and rapid depletion of the central plasma density are observed. Two-dimensional cross-correlation measurement shows that a mode with azimuthal mode number m =1 and large radial correlation length dominates the outward transport in these cases. Linear analysis based on a two-fluid Braginskii model suggests that the fluctuations are driven by both density gradient (drift wave like) and flow shear (Kelvin-Helmholtz like) at the plasma edge.

  14. Temporal variations of electron density and temperature in Kr/Ne/H2 photoionized plasma induced by nanosecond pulses from extreme ultraviolet source

    NASA Astrophysics Data System (ADS)

    Saber, I.; Bartnik, A.; Wachulak, P.; Skrzeczanowski, W.; Jarocki, R.; Fiedorowicz, H.

    2017-06-01

    Spectral investigations of low-temperature photoionized plasmas created in a Kr/Ne/H2 gas mixture were performed. The low-temperature plasmas were generated by gas mixture irradiation using extreme ultraviolet pulses from a laser-plasma source. Emission spectra in the ultraviolet/visible range from the photoionized plasmas contained lines that mainly corresponded to neutral atoms and singly charged ions. Temporal variations in the plasma electron temperature and electron density were studied using different characteristic emission lines at various delay times. Results, based on Kr II lines, showed that the electron temperature decreased from 1.7 to 0.9 eV. The electron densities were estimated using different spectral lines at each delay time. In general, except for the Hβ line, in which the electron density decreased from 3.78 × 1016 cm-3 at 200 ns to 5.77 × 1015 cm-3 at 2000 ns, most of the electron density values measured from the different lines were of the order of 1015 cm-3 and decreased slightly while maintaining the same order when the delay time increased. The time dependences of the measured and simulated intensities of a spectral line of interest were also investigated. The validity of the partial or full local thermodynamic equilibrium (LTE) conditions in plasma was explained based on time-resolved electron density measurements. The partial LTE condition was satisfied for delay times in the 200 ns to 1500 ns range. The results are summarized, and the dominant basic atomic processes in the gas mixture photoionized plasma are discussed.

  15. A Concept for Directly Coupled Pulsed Electromagnetic Acceleration of Plasmas

    NASA Technical Reports Server (NTRS)

    Thio, Y.C. Francis; Cassibry, Jason T.; Eskridge, Richard; Smith, James; Wu, S. T.; Rodgers, Stephen L. (Technical Monitor)

    2001-01-01

    Plasma jets with high momentum flux density are required for a variety of applications in propulsion research. Methods of producing these plasma jets are being investigated at NASA Marshall Space Flight Center. The experimental goal in the immediate future is to develop plasma accelerators which are capable of producing plasma jets with momentum flux density represented by velocities up to 200 km/s and ion density up to 10(exp 24) per cu m, with sufficient precision and reproducibility in their properties, and with sufficiently high efficiency. The jets must be sufficiently focused to allow them to be transported over several meters. A plasma accelerator concept is presented that might be able to meet these requirements. It is a self-switching, shaped coaxial pulsed plasma thruster, with focusing of the plasma flow by shaping muzzle current distribution as in plasma focus devices, and by mechanical tapering of the gun walls. Some 2-D MHD modeling in support of the conceptual design will be presented.

  16. Injection of a coaxial-gun-produced magnetized plasma into a background helicon plasma

    NASA Astrophysics Data System (ADS)

    Zhang, Yue; Lynn, Alan; Gilmore, Mark; Hsu, Scott

    2014-10-01

    A compact coaxial plasma gun is employed for experimental investigation of plasma bubble relaxation into a lower density background plasma. Experiments are being conducted in the linear device HelCat at UNM. The gun is powered by a 120-uF ignitron-switched capacitor bank, which is operated in a range of 5 to 10 kV and 100 kA. Multiple diagnostics are employed to investigate the plasma relaxation process. Magnetized argon plasma bubbles with velocities 1.2Cs, densities 1020 m-3 and electron temperature 13eV have been achieved. The background helicon plasma has density 1013 m-3, magnetic field from 200 to 500 Gauss and electron temperature 1eV. Several distinct operational regimes with qualitatively different dynamics are identified by fast CCD camera images. Additionally a B-dot probe array has been employed to measure the spatial toroidal and poloidal magnetic flux evolution to identify plasma bubble configurations. Experimental data and analysis will be presented.

  17. The study of helicon plasma source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miao Tingting; Shang Yong; Graduate University of Chinese Academy of Sciences, Beijing 100049

    2010-02-15

    Helicon plasma source is known as efficient generator of uniform and high density plasma. A helicon plasma source was developed for investigation of plasma neutralization and plasma lens in the Institute of Modern Physics in China. In this paper, the characteristics of helicon plasma have been studied by using Langmuir four-probe and a high argon plasma density up to 3.9x10{sup 13} cm{sup -3} have been achieved with the Nagoya type III antenna at the conditions of the magnetic intensity of 200 G, working gas pressure of 2.8x10{sup -3} Pa, and rf power of 1200 W with a frequency of 27.12more » MHz. In the experiment, the important phenomena have been found: for a given magnetic induction intensity, the plasma density became greater with the increase in rf power and tended to saturation, and the helicon mode appeared at the rf power between 200 and 400 W.« less

  18. Gas-filled capillaries for plasma-based accelerators

    NASA Astrophysics Data System (ADS)

    Filippi, F.; Anania, M. P.; Brentegani, E.; Biagioni, A.; Cianchi, A.; Chiadroni, E.; Ferrario, M.; Pompili, R.; Romeo, S.; Zigler, A.

    2017-07-01

    Plasma Wakefield Accelerators are based on the excitation of large amplitude plasma waves excited by either a laser or a particle driver beam. The amplitude of the waves, as well as their spatial dimensions and the consequent accelerating gradient depend strongly on the background electron density along the path of the accelerated particles. The process needs stable and reliable plasma sources, whose density profile must be controlled and properly engineered to ensure the appropriate accelerating mechanism. Plasma confinement inside gas filled capillaries have been studied in the past since this technique allows to control the evolution of the plasma, ensuring a stable and repeatable plasma density distribution during the interaction with the drivers. Moreover, in a gas filled capillary plasma can be pre-ionized by a current discharge to avoid ionization losses. Different capillary geometries have been studied to allow the proper temporal and spatial evolution of the plasma along the acceleration length. Results of this analysis obtained by varying the length and the number of gas inlets will be presented.

  19. Enhanced pair plasma generation in the relativistic transparency regime

    NASA Astrophysics Data System (ADS)

    Liu, W. Y.; Luo, W.; Yuan, T.; Yu, J. Y.; Chen, M.; Sheng, Z. M.

    2017-10-01

    Electron-positron ( e - e + ) pair plasma generation in the relativistic transparency regime in a thin foil with a fixed thickness irradiated by two counter-propagating laser pulses is investigated through multi-dimensional particle-in-cell simulations. It is shown that target transparency can significantly enhance the pair generation due to the formation of a stable standing wave. An optimum foil density of 200-280 n c (with nc being the critical plasma density of the incident laser at the wavelength of 1 μm) is found for enhanced e - e + pair generation for laser intensity around 10 PW. With such foil density, laser energy transformed to pair plasma formation is approximately four times higher than that with a foil density of 710 nc, while the laser energy transformed to γ-photons remains almost the same. Dense e - e + plasma with a density as high as 10 22 cm - 3 ( ≃ 10 n c ) can be produced accordingly. Comparison of pair plasma generation between cases with fundamental and double frequency driver lasers further demonstrates such an enhancement effect. It shows that when the duration of the laser pulse is relatively short, the double frequency driver can generate more pair plasmas due to the earlier excitation of relativistic transparency.

  20. Plasma diagnosis from thermal noise and limits on dust flux or mass in comet Giacobini-Zinner

    NASA Technical Reports Server (NTRS)

    Meyer-Vernet, N.; Couturier, P.; Hoang, S.; Perche, C.; Steinberg, J. L.; Fainberg, J.

    1986-01-01

    Thermal noise spectroscopy was used to measure the density and temperature of the main (cold) electron plasma population during two hours around the point of closest approach of the International Cometary Explorer (ICE) to comet Giacobini-Zinner. The time resolution was 18 seconds in the plasma tail and 54 seconds elsewhere. Near the tail axis, the maximum plasma density was 670/cu cm and the temperature slightly above one volt. Away from the axis, the plasma density dropped to 100/cu cm over 2000 km, then decreased to 10/cu cm over 15,000 km; at the plasma tail, the density fluctuated between 10 and 30/cu cm, and the temperature, between 100,000 and 400,000 K. No evidence was found of grain impact on the spacecraft or antennas in the plasma tail. This yields an upper limit for the dust flux or particle mass, indicating either fluxes or masses in the tail smaller than those implied by models or an anomalous grain structure. Outside the tail, and particularly near 100,000 km from its axis, impulsive noises indicating plasma turbulence were observed.

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