Sample records for traditional processing method

  1. Exploring Non-Traditional Learning Methods in Virtual and Real-World Environments

    ERIC Educational Resources Information Center

    Lukman, Rebeka; Krajnc, Majda

    2012-01-01

    This paper identifies the commonalities and differences within non-traditional learning methods regarding virtual and real-world environments. The non-traditional learning methods in real-world have been introduced within the following courses: Process Balances, Process Calculation, and Process Synthesis, and within the virtual environment through…

  2. A review of traditional and current methods used to potentially reduce toxicity of Aconitum roots in Traditional Chinese Medicine.

    PubMed

    Liu, Shuai; Li, Fei; Li, Yan; Li, Weifei; Xu, Jinkai; Du, Hong

    2017-07-31

    Aconitum species are well-known for their medicinal value and high lethal toxicity in many Asian countries, notably China, India and Japan. The tubers are only used after processing in Traditional Chinese Medicine (TCM). They can be used safely and effectively with the methods of decoction, rational compatibility, and correct processing based on traditional experiences and new technologies. However, high toxicological risks still remain due to improper preparation and usage in China and other countries. Therefore, there is a need to clarify the methods of processing and compatibility to ensure their effectiveness and minimize the potential risks. The aim of this paper is to provide a review of traditional and current methods used to potentially reduce toxicity of Aconitum roots in TCM. The use of Aconitum has been investigated and the methods of processing and compatibility throughout history, including recent research, have been reviewed. Using of the methods of rational preparation, reasonable compatibility, and proper processing based on traditional experiences and new technologies, can enable Aconitum to be used safely and effectively. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

  3. Bioactive lipids in the butter production chain from Parmigiano Reggiano cheese area.

    PubMed

    Verardo, Vito; Gómez-Caravaca, Ana M; Gori, Alessandro; Losi, Giuseppe; Caboni, Maria F

    2013-11-01

    Bovine milk contains hundreds of diverse components, including proteins, peptides, amino acids, lipids, lactose, vitamins and minerals. Specifically, the lipid composition is influenced by different variables such as breed, feed and technological process. In this study the fatty acid and phospholipid compositions of different samples of butter and its by-products from the Parmigiano Reggiano cheese area, produced by industrial and traditional churning processes, were determined. The fatty acid composition of samples manufactured by the traditional method showed higher levels of monounsaturated and polyunsaturated fatty acids compared with industrial samples. In particular, the contents of n-3 fatty acids and conjugated linoleic acids were higher in samples produced by the traditional method than in samples produced industrially. Sample phospholipid composition also varied between the two technological processes. Phosphatidylethanolamine was the major phospholipid in cream, butter and buttermilk samples obtained by the industrial process as well as in cream and buttermilk samples from the traditional process, while phosphatidylcholine was the major phospholipid in traditionally produced butter. This result may be explained by the different churning processes causing different types of membrane disruption. Generally, samples produced traditionally had higher contents of total phospholipids; in particular, butter produced by the traditional method had a total phospholipid content 33% higher than that of industrially produced butter. The samples studied represent the two types of products present in the Parmigiano Reggiano cheese area, where the industrial churning process is widespread compared with the traditional processing of Reggiana cow's milk. This is because Reggiana cow's milk production is lower than that of other breeds and the traditional churning process is time-consuming and economically disadvantageous. However, its products have been demonstrated to contain more bioactive lipids compared with products obtained from other breeds and by the industrial process. © 2013 Society of Chemical Industry.

  4. [Analysis and countermeasure for quality risk in process of traditional Chinese medicine preparations].

    PubMed

    Yang, Ming; Yang, Yuan-Zhen; Wang, Ya-Qi; Wu, Zhen-Feng; Wang, Xue-Cheng; Luo, Jing

    2017-03-01

    Product quality relies on not only testing methods,but also the design and development, production control and product manufacturing all aspects of logistics management. Quality comes from the process control level.Therefore, it is very important to accurately identify the factors that may induce quality risk in the production process and quality control measures correspondingly.This article systematically analyzes the source of the quality risk of all aspects of the production process in traditional Chinese medicine preparation. Discussing ways and methods of quality risk identification of traditional Chinese medicine preparation and providing references for perfecting the whole process quality management of traditional Chinese medicine preparation. Copyright© by the Chinese Pharmaceutical Association.

  5. Actively Teaching Research Methods with a Process Oriented Guided Inquiry Learning Approach

    ERIC Educational Resources Information Center

    Mullins, Mary H.

    2017-01-01

    Active learning approaches have shown to improve student learning outcomes and improve the experience of students in the classroom. This article compares a Process Oriented Guided Inquiry Learning style approach to a more traditional teaching method in an undergraduate research methods course. Moving from a more traditional learning environment to…

  6. Comparative study on the nutritional and antioxidant properties of two Mexican corn (Zea mays) based meals versus processed cereals.

    PubMed

    Sánchez-Herrera, Marissa; Martínez-Cano, Evelia; Maldonado-Santoyo, María; Aparicio-Fernández, Xochitl

    2014-06-01

    The present study was conducted to analyze the chemical composition, total phenolics content and antioxidant capacity of two whole corn (Zea mays) based meals traditional from Mexico: "traditional pinole" and "seven grain pinole"; and compare it with information available from ready to eat cereal products based on refined corn and whole grain cereals. Proximate analyses (moisture, ash, fat, protein and fiber) were carried out according to the procedures of AOAC, sugars content was determined by HPLC method; calcium and iron were quantified using atomic absorption spectroscopy. Total phenolic compounds were determined by Folin-Ciocalteu spectrophotometric method; the antiradical capacity was determined by DPPH colorimetric method and total antioxidant capacity was determined by FRAP method. Traditional and seven grain pinole presented higher energy content and nutrient density (protein and fat) than processed cereals. Calcium content was higher in processed cereals than pinole; seven grain pinole presented the highest conentration of iron. Polyphenolic concentration was higher in both kinds of pinole compared to processed cereals; traditional pinole presented the highest antioxidant activity measured by DPPH and FRAP methods. The results provide evidence about the important nutrient and antioxidant content of traditional and seven grain pinole compared to processed cereals based on corn and other grains. It is recommended their incorporation in to regular diet as a healthy food, with a good protein level, low sugar content and good antioxidant capacity.

  7. Soft tissue deformation estimation by spatio-temporal Kalman filter finite element method.

    PubMed

    Yarahmadian, Mehran; Zhong, Yongmin; Gu, Chengfan; Shin, Jaehyun

    2018-01-01

    Soft tissue modeling plays an important role in the development of surgical training simulators as well as in robot-assisted minimally invasive surgeries. It has been known that while the traditional Finite Element Method (FEM) promises the accurate modeling of soft tissue deformation, it still suffers from a slow computational process. This paper presents a Kalman filter finite element method to model soft tissue deformation in real time without sacrificing the traditional FEM accuracy. The proposed method employs the FEM equilibrium equation and formulates it as a filtering process to estimate soft tissue behavior using real-time measurement data. The model is temporally discretized using the Newmark method and further formulated as the system state equation. Simulation results demonstrate that the computational time of KF-FEM is approximately 10 times shorter than the traditional FEM and it is still as accurate as the traditional FEM. The normalized root-mean-square error of the proposed KF-FEM in reference to the traditional FEM is computed as 0.0116. It is concluded that the proposed method significantly improves the computational performance of the traditional FEM without sacrificing FEM accuracy. The proposed method also filters noises involved in system state and measurement data.

  8. Effects of the traditional method and an alternative parboiling process on the fatty acids, vitamin E, γ-oryzanol and phenolic acids of glutinous rice.

    PubMed

    Thammapat, Pornpisanu; Meeso, Naret; Siriamornpun, Sirithon

    2016-03-01

    The impacts of traditional and alternative parboiling processes on the concentrations of fatty acids, tocopherol, tocotrienol, γ-oryzanol and phenolic acids in glutinous rice were investigated. Differences between the two methods were the soaking temperatures and the steaming methods. Results showed that parboiling processes significantly increased the concentrations of saturated fatty acids (SFA), mono-unsaturated fatty acids (MUFA), γ-oryzanol, γ-tocotrienol and total phenolic acids (TPA) in glutinous rice, while α-tocopherol, γ-tocopherol and polyunsaturated fatty acids (PUFA) decreased (p<0.05). Both the traditional and alternative parboiling methods increased the levels of γ-oryzanol by three or fourfold compared with the level of γ-oryzanol in raw rice. Parboiling caused both adverse and favorable effects on phenolic acids content (p<0.05). We found that glutinous rice, parboiled using our newly developed method, had higher levels of PUFA, total vitamin E, γ-oryzanol, hydrobenzoic acid, hydroxycinnamic acid and TPA compared to the traditional method. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. A comparative study on the traditional Indian Shodhana and Chinese processing methods for aconite roots by characterization and determination of the major components

    PubMed Central

    2013-01-01

    Background Aconitum is an indispensable entity of the traditional medicine therapy in Ayurveda and Traditional Chinese medicine (TCM), in spite of its known fatal toxicity characteristics. The prolonged use of this drug, irrespective of its known lethal effects, is governed by the practice of effective detoxification processes that have been used for decades. However, the processing methods of Ayurveda and TCM are different, and no comparative study has been carried out to evaluate their differences. The objective of the present study was to carry out comparative chemical profiling of the roots of Aconitum heterophyllum Wall, A. carmichaelii Debx., and A. kusnezoffii Reichb. after application of two detoxification methods used in Ayurveda and one method used in TCM . Results Analysis of the processed samples was carried out by ultra-high performance liquid chromatography combined with quadrupole time-of-flight mass spectrometry (UHPLC-QTOF/MS). The results obtained in the study demonstrate that all three processing methods used in Ayurveda and TCM effectively extract the diester diterpenoid alkaloids and led to their conversion into monoester diterpenoid alkaloids. The efficiency of the processes in reduction of toxic alkaloid contents can be stated as: Processing with water > Shodhana with cow milk > Shodhana with cow urine. The analysis method was validated as per ICH-Q2R1 guidelines and all the parameters were found to comply with the recommendations stated in the guidelines. Conclusions There have been no reports till date, to compare the processing methods used in Ayurveda with the methods used in TCM for detoxification of aconite roots. Our study demonstrates that, these methods used in both the traditional systems of medicine, efficiently detoxify the aconite roots. Amongst the three selected procedures, the TCM method of decoction with water is the most efficient. Through experimental evidences, we prove the conversion of toxic diester diterpenoid alkaloids to relatively safer monoester diterpenoid alkaloids. Thus, this study demonstrates that comparative study on the traditional experiences accumulated in different medical systems is useful for expanding their respective applications. PMID:24156713

  10. [Comparison of analgesic effect between locally vinegar-processed preparation of fresh rhizoma Corydalis and traditionally vinegar-processed rhizoma Corydalis].

    PubMed

    Liu, L; Li, G; Zhu, F; Wang, L; Wang, Y

    1990-11-01

    Hot plate and writhing methods were used in the comparison of the analgesic effect of vinegar-processed fresh tuber corydalis and the traditionally vinegar-processed Rhizoma Corydalis. The result shows that the effect of the former is stronger than that of the latter.

  11. Proposed correlation of modern processing principles for Ayurvedic herbal drug manufacturing: A systematic review.

    PubMed

    Jain, Rahi; Venkatasubramanian, Padma

    2014-01-01

    Quality Ayurvedic herbal medicines are potential, low-cost solutions for addressing contemporary healthcare needs of both Indian and global community. Correlating Ayurvedic herbal preparations with modern processing principles (MPPs) can help develop new and use appropriate technology for scaling up production of the medicines, which is necessary to meet the growing demand. Understanding the fundamental Ayurvedic principles behind formulation and processing is also important for improving the dosage forms. Even though Ayurvedic industry has adopted technologies from food, chemical and pharmaceutical industries, there is no systematic study to correlate the traditional and modern processing methods. This study is an attempt to provide a possible correlation between the Ayurvedic processing methods and MPPs. A systematic literature review was performed to identify the Ayurvedic processing methods by collecting information from English editions of classical Ayurveda texts on medicine preparation methods. Correlation between traditional and MPPs was done based on the techniques used in Ayurvedic drug processing. It was observed that in Ayurvedic medicine preparations there were two major types of processes, namely extraction, and separation. Extraction uses membrane rupturing and solute diffusion principles, while separation uses volatility, adsorption, and size-exclusion principles. The study provides systematic documentation of methods used in Ayurveda for herbal drug preparation along with its interpretation in terms of MPPs. This is the first step which can enable improving or replacing traditional techniques. New technologies or use of existing technologies can be used to improve the dosage forms and scaling up while maintaining the Ayurvedic principles similar to traditional techniques.

  12. Eventogram: A Visual Representation of Main Events in Biomedical Signals.

    PubMed

    Elgendi, Mohamed

    2016-09-22

    Biomedical signals carry valuable physiological information and many researchers have difficulty interpreting and analyzing long-term, one-dimensional, quasi-periodic biomedical signals. Traditionally, biomedical signals are analyzed and visualized using periodogram, spectrogram, and wavelet methods. However, these methods do not offer an informative visualization of main events within the processed signal. This paper attempts to provide an event-related framework to overcome the drawbacks of the traditional visualization methods and describe the main events within the biomedical signal in terms of duration and morphology. Electrocardiogram and photoplethysmogram signals are used in the analysis to demonstrate the differences between the traditional visualization methods, and their performance is compared against the proposed method, referred to as the " eventogram " in this paper. The proposed method is based on two event-related moving averages that visualizes the main time-domain events in the processed biomedical signals. The traditional visualization methods were unable to find dominant events in processed signals while the eventogram was able to visualize dominant events in signals in terms of duration and morphology. Moreover, eventogram -based detection algorithms succeeded with detecting main events in different biomedical signals with a sensitivity and positive predictivity >95%. The output of the eventogram captured unique patterns and signatures of physiological events, which could be used to visualize and identify abnormal waveforms in any quasi-periodic signal.

  13. Evaluation of toxicity of ‘Vatsanabha’ (Aconitum ferox, Ranunculaceae) Before and After Shodhana

    PubMed Central

    Deore, S.L.; Moon, K.V.; Khadabadi, S.S.; Deokate, U.A.; Baviskar, B.A.

    2013-01-01

    Ayurvedic preparations contain toxic elements like heavy metals and other chemicals exceeding their permissible limits. Ayurvedic method of detoxification of such products involves Shodhana. Hence, in present paper it has been decided to replace Ayurvedic Shodhana process by chemical purification method and to study the benefits and/or drawbacks of the traditional Ayurvedic Shodhana process. Crude aconite root, Ayurvedic Shodhana treated aconite root and chemical Shodhana treated aconite root samples were evaluated for toxicity and changes by animal studies and thin layer chromatography (TLC) respectively. The results of the toxicity study suggest that the modified method of Shodhana is less efficient as compared to the traditional Ayurvedic Shodhana process. TLC studies have shown that pseudoaconitine and aconitine were converted into far less toxic substances like veratroyl pseudoaconine and benzoylaconine respectively only in traditional Ayurvedic Shodhana. PMID:24023444

  14. Reduce conflicts in traditional merariq traditions through the long tradition of the tribal people of sasak lombok

    NASA Astrophysics Data System (ADS)

    Sarmini; Nadiroh, Ulin; Saeun Fahmi, Muhammad

    2018-01-01

    Marriage is a container for framing the inner-to-heart relationship, the bond of love and affection between a man and woman to nurture a joy of happiness. This study aims to find out how the process and stages in traditional merariq traditions in the Sasak people, conflicts arising from merariq traditions, and reduce conflict through the tradition of selabar. The method used in this research is qualitative analysis method. In the process, merariq tradition is done by kidnapping the bride without the knowledge of the parents or the family of the women. There are several stages that must be passed by the bride and groom in the tradition merariq, namely: besejati, nyelabar, bait wali, sorong serah dan nyongkolang. Conflict that often arises, for internal family, merariq often become a place of coercion against the female family. For society, merariq impact on disruption of harmony of social life. In order to reduce the conflicts done selabar tradition, the tragedy is regarded as an alternative problem solving in the form of negotiations between the bride and groom’s family and the bride-to-be relating to ajikrame and pisuke transactions.

  15. How Many Batches Are Needed for Process Validation under the New FDA Guidance?

    PubMed

    Yang, Harry

    2013-01-01

    The newly updated FDA Guidance for Industry on Process Validation: General Principles and Practices ushers in a life cycle approach to process validation. While the guidance no longer considers the use of traditional three-batch validation appropriate, it does not prescribe the number of validation batches for a prospective validation protocol, nor does it provide specific methods to determine it. This potentially could leave manufacturers in a quandary. In this paper, I develop a Bayesian method to address the issue. By combining process knowledge gained from Stage 1 Process Design (PD) with expected outcomes of Stage 2 Process Performance Qualification (PPQ), the number of validation batches for PPQ is determined to provide a high level of assurance that the process will consistently produce future batches meeting quality standards. Several examples based on simulated data are presented to illustrate the use of the Bayesian method in helping manufacturers make risk-based decisions for Stage 2 PPQ, and they highlight the advantages of the method over traditional Frequentist approaches. The discussions in the paper lend support for a life cycle and risk-based approach to process validation recommended in the new FDA guidance. The newly updated FDA Guidance for Industry on Process Validation: General Principles and Practices ushers in a life cycle approach to process validation. While the guidance no longer considers the use of traditional three-batch validation appropriate, it does not prescribe the number of validation batches for a prospective validation protocol, nor does it provide specific methods to determine it. This potentially could leave manufacturers in a quandary. In this paper, I develop a Bayesian method to address the issue. By combining process knowledge gained from Stage 1 Process Design (PD) with expected outcomes of Stage 2 Process Performance Qualification (PPQ), the number of validation batches for PPQ is determined to provide a high level of assurance that the process will consistently produce future batches meeting quality standards. Several examples based on simulated data are presented to illustrate the use of the Bayesian method in helping manufacturers make risk-based decisions for Stage 2 PPQ, and THEY highlight the advantages of the method over traditional Frequentist approaches. The discussions in the paper lend support for a life cycle and risk-based approach to process validation recommended in the new FDA guidance.

  16. School Improvement Model to Foster Student Learning

    ERIC Educational Resources Information Center

    Rulloda, Rudolfo Barcena

    2011-01-01

    Many classroom teachers are still using the traditional teaching methods. The traditional teaching methods are one-way learning process, where teachers would introduce subject contents such as language arts, English, mathematics, science, and reading separately. However, the school improvement model takes into account that all students have…

  17. [Perspective and application of metabonomics in modern study of traditional Chinese medicine].

    PubMed

    Qin, Kun-Ming; Wang, Bin; Chen, Lin-Wei; Zhang, Mao-Sen; Yang, Guang-Ming; Shu, Ya-Chun; Cai, Bao-Chang

    2014-08-01

    Metabonomics is a new method to study on the metabolic network and the relationship between body and environment, which conforms to the way of traditional Chinese medicine (TCM) research. In the study process of modernization of traditional Chinese medicine, effectively conjunction with metabonomics method will facilitate the integration of TCM with modern biological science and technology, and promote the modernization of TCM. This paper introduce the application of metabonomics in the research of toxicity mechanism of TCM, compatibility mechanism of TCM formula, pharmacology effect of TCM and processing mechanism of TCM. This paper summarize the problems in the TCM metabonomics research and prospect its bright future.

  18. [Current situations and problem analysis of influencing factors of traditional Chinese medicine tablets on forming quality].

    PubMed

    Li, Yan-Nian; Wu, Zhen-Feng; Wan, Na; Li, Yuan-Hui; Li, Hui-Ting; Yang, Ming

    2018-04-01

    The compressibility of tablets is the essential operating unit during the preparation of traditional Chinese medicine tablets, as well as a complicated process. Therefore, it is of great significance to comprehensively study the influencing factors on the formation process. This paper aimed to review the evaluation methods for the tablet forming quality and highlight the effects of material powder properties, excipients and preparation technology on the quality of traditional Chinese medicine tablets on the basis of relevant literatures. Furthermore, the common problems in tablet forming process are also analyzed to provide useful references for the development of tablet forming quality of traditional Chinese medicines. Copyright© by the Chinese Pharmaceutical Association.

  19. Failure mode and effects analysis: a comparison of two common risk prioritisation methods.

    PubMed

    McElroy, Lisa M; Khorzad, Rebeca; Nannicelli, Anna P; Brown, Alexandra R; Ladner, Daniela P; Holl, Jane L

    2016-05-01

    Failure mode and effects analysis (FMEA) is a method of risk assessment increasingly used in healthcare over the past decade. The traditional method, however, can require substantial time and training resources. The goal of this study is to compare a simplified scoring method with the traditional scoring method to determine the degree of congruence in identifying high-risk failures. An FMEA of the operating room (OR) to intensive care unit (ICU) handoff was conducted. Failures were scored and ranked using both the traditional risk priority number (RPN) and criticality-based method, and a simplified method, which designates failures as 'high', 'medium' or 'low' risk. The degree of congruence was determined by first identifying those failures determined to be critical by the traditional method (RPN≥300), and then calculating the per cent congruence with those failures designated critical by the simplified methods (high risk). In total, 79 process failures among 37 individual steps in the OR to ICU handoff process were identified. The traditional method yielded Criticality Indices (CIs) ranging from 18 to 72 and RPNs ranging from 80 to 504. The simplified method ranked 11 failures as 'low risk', 30 as medium risk and 22 as high risk. The traditional method yielded 24 failures with an RPN ≥300, of which 22 were identified as high risk by the simplified method (92% agreement). The top 20% of CI (≥60) included 12 failures, of which six were designated as high risk by the simplified method (50% agreement). These results suggest that the simplified method of scoring and ranking failures identified by an FMEA can be a useful tool for healthcare organisations with limited access to FMEA expertise. However, the simplified method does not result in the same degree of discrimination in the ranking of failures offered by the traditional method. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  20. The Oshun Festival: An African Traditional Religious Healing Process.

    ERIC Educational Resources Information Center

    Idowu, Adeyemi I.

    1992-01-01

    Examines the Oshun Festival, an African traditional religious festival, from a healing perspective. Highlights the value of religion in the African culture and discusses various myths. Explores the role of myths in and the place of beliefs in the healing process. Explains rituals and the healing environment, healers, and healing methods. Offers…

  1. Effect of a traditional processing method on the chemical composition of local white lupin (Lupinus albus L.) seed in North-Western Ethiopia.

    PubMed

    Yeheyis, Likawent; Kijora, Claudia; Wink, Michael; Peters, Kurt J

    2011-01-01

    The effect of a traditional Ethiopian lupin processing method on the chemical composition of lupin seed samples was studied. Two sampling districts, namely Mecha and Sekela, representing the mid- and high-altitude areas of north-western Ethiopia, respectively, were randomly selected. Different types of traditionally processed and marketed lupin seed samples (raw, roasted, and finished) were collected in six replications from each district. Raw samples are unprocessed, and roasted samples are roasted using firewood. Finished samples are those ready for human consumption as snack. Thousand seed weight for raw and roasted samples within a study district was similar (P > 0.05), but it was lower (P < 0.01) for finished samples compared to raw and roasted samples. The crude fibre content of finished lupin seed sample from Mecha was lower (P < 0.01) than that of raw and roasted samples. However, the different lupin samples from Sekela had similar crude fibre content (P > 0.05). The crude protein and crude fat contents of finished samples within a study district were higher (P < 0.01) than those of raw and roasted samples, respectively. Roasting had no effect on the crude protein content of lupin seed samples. The crude ash content of raw and roasted lupin samples within a study district was higher (P < 0.01) than that of finished lupin samples of the respective study districts. The content of quinolizidine alkaloids of finished lupin samples was lower than that of raw and roasted samples. There was also an interaction effect between location and lupin sample type. The traditional processing method of lupin seeds in Ethiopia has a positive contribution improving the crude protein and crude fat content, and lowering the alkaloid content of the finished product. The study showed the possibility of adopting the traditional processing method to process bitter white lupin for the use as protein supplement in livestock feed in Ethiopia, but further work has to be done on the processing method and animal evaluation.

  2. Knowledge Transfer in Online Learning Environments

    ERIC Educational Resources Information Center

    Hansen, David E.

    2008-01-01

    Research comparing online and traditional course delivery methods has sought to demonstrate the equivalence of student performance in online and traditional courses. This study examines the unique proposition that online course delivery is superior to traditional when it comes to applied learning and is thus superior in the process of knowledge…

  3. [Study on culture and philosophy of processing of traditional Chinese medicines].

    PubMed

    Yang, Ming; Zhang, Ding-Kun; Zhong, Ling-Yun; Wang, Fang

    2013-07-01

    According to cultural views and philosophical thoughts, this paper studies the cultural origin, thinking modes, core principles, general regulation and methods of processing, backtracks processing's culture and history which contains generation and deduction process, experienced and promoting process, and core value, summarizes processing's basic principles which are directed by holistic, objective, dynamic, balanced and appropriate thoughts; so as to propagate cultural characteristic and philosophical wisdom of traditional Chinese medicine processing, to promote inheritance and development of processing and to ensure the maximum therapeutic value of Chinese medical clinical.

  4. Comparison of traditional nondestructive analysis of RERTR fuel plates with digital radiographic techniques

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Davidsmeier, T.; Koehl, R.; Lanham, R.

    2008-07-15

    The current design and fabrication process for RERTR fuel plates utilizes film radiography during the nondestructive testing and characterization. Digital radiographic methods offer a potential increases in efficiency and accuracy. The traditional and digital radiographic methods are described and demonstrated on a fuel plate constructed with and average of 51% by volume fuel using the dispersion method. Fuel loading data from each method is analyzed and compared to a third baseline method to assess accuracy. The new digital method is shown to be more accurate, save hours of work, and provide additional information not easily available in the traditional method.more » Additional possible improvements suggested by the new digital method are also raised. (author)« less

  5. A Metallurgical Study of Nāga Bhasma

    PubMed Central

    Singh Gautam, Dev Nath

    2017-01-01

    Background: The metal Nāga (Lead) is being used by Indians since ancient times. Its external and internal uses have been described in Caraka, Suśruta and other Ayurvedic Saṃhitā. According to most of the Rasa texts, Nāga Bhasma and its formulations are used in many diseases such as Prameha, Jvara, Gulma, Śukrameha etc. Objectives: In the present study, Nāga Bhasma was prepared by the traditional Puṭa method (TPM) and by the electric muffle furnace Puṭa method (EMFPM) and standardized using Metallographic studies. Doing so helps in the study of the microstructure of Nāga Bhasma and also helps in the identification of the metal particles along with the nature of compound formed during the Māraṇa (Bhasmīkaraṇa) process. Setting and Design: Different samples from initial raw material to final product of Nāga Bhasma were collected during the pharmaceutical process (1st, 30th and 60th Puṭa) from both methods i.e. TPM and EMFPM. Samples from both methods were studied using metallographic examination. Materials and Methods: The processing of the Nāga Bhasma (ṣaṣṭipuṭa) was done according to Ānanda Kanda[9] Samples from the raw material i.e. Aśodhita Nāga (raw Lead) and that processed after 1st, 30th and 60th Puṭa from both methods i.e. traditional Puṭa method (using heat from burning of cow dung cakes) and electric muffle furnace Puṭa method were taken. They were mounted on self hardening acrylic base. After careful polishing to obtain scratch free surface of product, they were used for metallurgical study. Conclusion: This study shows that traditional Puṭa method may be better than electric muffle furnace Puṭa method because of more homogeneous distribution of Lead sulphide in the Nāga Bhasma which is prepared by traditional method. PMID:29269968

  6. Comparative Study of Powdered Ginger Drink Processed by Different Method:Traditional and using Evaporation Machine

    NASA Astrophysics Data System (ADS)

    Apriyana, Wuri; Taufika Rosyida, Vita; Nur Hayati, Septi; Darsih, Cici; Dewi Poeloengasih, Crescentiana

    2017-12-01

    Ginger drink is one of the traditional beverage that became one of the products of interest by consumers in Indonesia. This drink is believed to have excellent properties for the health of the body. In this study, we have compared the moisture content, ash content, metal content and the identified compound of product which processed with traditional technique and using an evaporator machine. The results show that both of products fulfilled some parameters of the Indonesian National Standard for the traditional powdered drink. GC-MS analysis data showed the identified compound of both product. The major of hydrocarbon groups that influenced the flavor such as zingiberene, camphene, beta-phelladrine, beta-sesquepelladrine, curcumene, and beta-bisabolene were found higher in ginger drink powder treated with a machine than those processed traditionally.

  7. Research on the selection of innovation compound using Possibility Construction Space Theory and fuzzy pattern recognition

    NASA Astrophysics Data System (ADS)

    Xie, Songhua; Li, Dehua; Nie, Hui

    2009-10-01

    There are a large number of fuzzy concepts and fuzzy phenomena in traditional Chinese medicine, which have led to great difficulties for study of traditional Chinese medicine. In this paper, the mathematical methods are used to quantify fuzzy concepts of drugs and prescription. We put forward the process of innovation formulations and selection method in Chinese medicine based on the Possibility Construction Space Theory (PCST) and fuzzy pattern recognition. Experimental results show that the method of selecting medicines from a number of characteristics of traditional Chinese medicine is consistent with the basic theory of traditional Chinese medicine. The results also reflect the integrated effects of the innovation compound. Through the use of the innovation formulations system, we expect to provide software tools for developing new traditional Chinese medicine and to inspire traditional Chinese medicine researchers to develop novel drugs.

  8. GIS Based Distributed Runoff Predictions in Variable Source Area Watersheds Employing the SCS-Curve Number

    NASA Astrophysics Data System (ADS)

    Steenhuis, T. S.; Mendoza, G.; Lyon, S. W.; Gerard Marchant, P.; Walter, M. T.; Schneiderman, E.

    2003-04-01

    Because the traditional Soil Conservation Service Curve Number (SCS-CN) approach continues to be ubiquitously used in GIS-BASED water quality models, new application methods are needed that are consistent with variable source area (VSA) hydrological processes in the landscape. We developed within an integrated GIS modeling environment a distributed approach for applying the traditional SCS-CN equation to watersheds where VSA hydrology is a dominant process. Spatial representation of hydrologic processes is important for watershed planning because restricting potentially polluting activities from runoff source areas is fundamental to controlling non-point source pollution. The methodology presented here uses the traditional SCS-CN method to predict runoff volume and spatial extent of saturated areas and uses a topographic index to distribute runoff source areas through watersheds. The resulting distributed CN-VSA method was incorporated in an existing GWLF water quality model and applied to sub-watersheds of the Delaware basin in the Catskill Mountains region of New York State. We found that the distributed CN-VSA approach provided a physically-based method that gives realistic results for watersheds with VSA hydrology.

  9. [Investigation on production process quality control of traditional Chinese medicine--Banlangen granule as an example].

    PubMed

    Tan, Manrong; Yan, Dan; Qiu, Lingling; Chen, Longhu; Yan, Yan; Jin, Cheng; Li, Hanbing; Xiao, Xiaohe

    2012-04-01

    For the quality management system of herbal medicines, intermediate and finished products it exists the " short board" effect of methodologies. Based on the concept of process control, new strategies and new methods of the production process quality control had been established with the consideration of the actual production of traditional Chinese medicine an the characteristics of Chinese medicine. Taking Banlangen granule as a practice example, which was effective and widespread application, character identification, determination of index components, chemical fingerprint and biometrics technology were sequentially used respectively to assess the quality of Banlangen herbal medicines, intermediate (water extraction and alcohol precipitation) and finished product. With the transfer rate of chemical information and biological potency as indicators, the effectiveness and transmission of the above different assessments and control methods had been researched. And ultimately, the process quality control methods of Banlangen granule, which were based on chemical composition analysis-biometric analysis, had been set up. It can not only validly solute the current status that there were many manufacturers varying quality of Banlangen granule, but also ensure and enhance its clinical efficacy. Furthermore it provided a foundation for the construction of the quality control of traditional Chinese medicine production process.

  10. A Metallurgical Study of Nāga Bhasma.

    PubMed

    Singh Gautam, Dev Nath

    2017-01-01

    The metal Nāga (Lead) is being used by Indians since ancient times. Its external and internal uses have been described in Caraka, Suśruta and other Ayurvedic Saṃhitā . According to most of the Rasa texts, Nāga Bhasma and its formulations are used in many diseases such as Prameha , Jvara , Gulma , Śukrameha etc. In the present study, Nāga Bhasma was prepared by the traditional Puṭa method (TPM) and by the electric muffle furnace Puṭa method (EMFPM) and standardized using Metallographic studies. Doing so helps in the study of the microstructure of Nāga Bhasma and also helps in the identification of the metal particles along with the nature of compound formed during the Māraṇa (Bhasmīkaraṇa) process. Different samples from initial raw material to final product of Nāga Bhasma were collected during the pharmaceutical process (1 st , 30 th and 60 th Puṭa ) from both methods i.e. TPM and EMFPM. Samples from both methods were studied using metallographic examination. The processing of the Nāga Bhasma ( ṣaṣṭipuṭa ) was done according to Ānanda Kanda [9] Samples from the raw material i.e. Aśodhita Nāga (raw Lead) and that processed after 1 st , 30 th and 60 th Puṭa from both methods i.e. traditional Puṭa method (using heat from burning of cow dung cakes) and electric muffle furnace Puṭa method were taken. They were mounted on self hardening acrylic base. After careful polishing to obtain scratch free surface of product, they were used for metallurgical study. This study shows that traditional Puṭa method may be better than electric muffle furnace Puṭa method because of more homogeneous distribution of Lead sulphide in the Nāga Bhasma which is prepared by traditional method.

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jacques Hugo

    Traditional engineering methods do not make provision for the integration of human considerations, while traditional human factors methods do not scale well to the complexity of large-scale nuclear power plant projects. Although the need for up-to-date human factors engineering processes and tools is recognised widely in industry, so far no formal guidance has been developed. This article proposes such a framework.

  12. The Feasibility of Applying PBL Teaching Method to Surgery Teaching of Chinese Medicine

    ERIC Educational Resources Information Center

    Tang, Qianli; Yu, Yuan; Jiang, Qiuyan; Zhang, Li; Wang, Qingjian; Huang, Mingwei

    2008-01-01

    The traditional classroom teaching mode is based on the content of the subject, takes the teacher as the center and gives priority to classroom instruction. While PBL (Problem Based Learning) teaching method breaches the traditional mode, combining the basic science with clinical practice and covering the process from discussion to self-study to…

  13. A modified indirect mathematical model for evaluation of ethanol production efficiency in industrial-scale continuous fermentation processes.

    PubMed

    Canseco Grellet, M A; Castagnaro, A; Dantur, K I; De Boeck, G; Ahmed, P M; Cárdenas, G J; Welin, B; Ruiz, R M

    2016-10-01

    To calculate fermentation efficiency in a continuous ethanol production process, we aimed to develop a robust mathematical method based on the analysis of metabolic by-product formation. This method is in contrast to the traditional way of calculating ethanol fermentation efficiency, where the ratio between the ethanol produced and the sugar consumed is expressed as a percentage of the theoretical conversion yield. Comparison between the two methods, at industrial scale and in sensitivity studies, showed that the indirect method was more robust and gave slightly higher fermentation efficiency values, although fermentation efficiency of the industrial process was found to be low (~75%). The traditional calculation method is simpler than the indirect method as it only requires a few chemical determinations in samples collected. However, a minor error in any measured parameter will have an important impact on the calculated efficiency. In contrast, the indirect method of calculation requires a greater number of determinations but is much more robust since an error in any parameter will only have a minor effect on the fermentation efficiency value. The application of the indirect calculation methodology in order to evaluate the real situation of the process and to reach an optimum fermentation yield for an industrial-scale ethanol production is recommended. Once a high fermentation yield has been reached the traditional method should be used to maintain the control of the process. Upon detection of lower yields in an optimized process the indirect method should be employed as it permits a more accurate diagnosis of causes of yield losses in order to correct the problem rapidly. The low fermentation efficiency obtained in this study shows an urgent need for industrial process optimization where the indirect calculation methodology will be an important tool to determine process losses. © 2016 The Society for Applied Microbiology.

  14. An Assessment of Nondestructive Evaluation Capability for Complex Additive Manufacturing Aerospace Components

    NASA Technical Reports Server (NTRS)

    Walker, James; Beshears, Ron; Lambert, Dennis; Tilson, William

    2016-01-01

    The primary focus of this work is to investigate some of the fundamental relationships between processing, mechanical testing, materials characterization, and NDE for additively manufactured (AM) components using the powder bed fusion direct melt laser sintered process. The goal is to understand the criticality of defects unique to the AM process and then how conventional nondestructive evaluation methods as well as some of the more non-traditional methods such as computed tomography, are effected by the AM material. Specific defects including cracking, porosity and partially/unfused powder will be addressed. Besides line-of-site NDE, as appropriate these inspection capabilities will be put into the context of complex AM geometries where hidden features obscure, or inhibit traditional NDE methods.

  15. Using a topographic index to distribute variable source area runoff predicted with the SCS curve-number equation

    NASA Astrophysics Data System (ADS)

    Lyon, Steve W.; Walter, M. Todd; Gérard-Marchant, Pierre; Steenhuis, Tammo S.

    2004-10-01

    Because the traditional Soil Conservation Service curve-number (SCS-CN) approach continues to be used ubiquitously in water quality models, new application methods are needed that are consistent with variable source area (VSA) hydrological processes in the landscape. We developed and tested a distributed approach for applying the traditional SCS-CN equation to watersheds where VSA hydrology is a dominant process. Predicting the location of source areas is important for watershed planning because restricting potentially polluting activities from runoff source areas is fundamental to controlling non-point-source pollution. The method presented here used the traditional SCS-CN approach to predict runoff volume and spatial extent of saturated areas and a topographic index, like that used in TOPMODEL, to distribute runoff source areas through watersheds. The resulting distributed CN-VSA method was applied to two subwatersheds of the Delaware basin in the Catskill Mountains region of New York State and one watershed in south-eastern Australia to produce runoff-probability maps. Observed saturated area locations in the watersheds agreed with the distributed CN-VSA method. Results showed good agreement with those obtained from the previously validated soil moisture routing (SMR) model. When compared with the traditional SCS-CN method, the distributed CN-VSA method predicted a similar total volume of runoff, but vastly different locations of runoff generation. Thus, the distributed CN-VSA approach provides a physically based method that is simple enough to be incorporated into water quality models, and other tools that currently use the traditional SCS-CN method, while still adhering to the principles of VSA hydrology.

  16. Analysis of preparation of Chinese traditional medicine based on the fiber fingerprint drop trace

    NASA Astrophysics Data System (ADS)

    Zhang, Zhilin; Wang, Jialu; Sun, Weimin; Yan, Qi

    2010-11-01

    The purpose of the fiber micro-drop analyzing technique is to measure the characteristics of liquids using optical methods. The fiber fingerprint drop trace (FFDT) is a curve of light intensity vs. time. This curve indicates the forming, growing and dripping processes of the liquid drops. A pair of fibers was used to monitor the dripping process. The FFDTs are acquired and analyzed by a computer. Different liquid samples of many kinds of preparation of Chinese traditional medicines were tested by using the fiber micro-drop sensor in the experiments. The FFDTs of preparation of Chinese traditional medicines with different concentrations were analyzed in different ways. Considering the characters of the FFDTs, a novel method is proposed to measure the different preparation of Chinese traditional medicines and its concentration based on the corresponding relationship of FFDTs and the physical and chemical parameters of the liquids.

  17. [Construction of research system for processing mechanism of traditional Chinese medicine based on chemical composition transformation combined with intestinal absorption barrier].

    PubMed

    Sun, E; Xu, Feng-Juan; Zhang, Zhen-Hai; Wei, Ying-Jie; Tan, Xiao-Bin; Cheng, Xu-Dong; Jia, Xiao-Bin

    2014-02-01

    Based on practice of Epimedium processing mechanism for many years and integrated multidisciplinary theory and technology, this paper initially constructs the research system for processing mechanism of traditional Chinese medicine based on chemical composition transformation combined with intestinal absorption barrier, which to form an innovative research mode of the " chemical composition changes-biological transformation-metabolism in vitro and in vivo-intestinal absorption-pharmacokinetic combined pharmacodynamic-pharmacodynamic mechanism". Combined with specific examples of Epimedium and other Chinese herbal medicine processing mechanism, this paper also discusses the academic thoughts, research methods and key technologies of this research system, which will be conducive to systematically reveal the modem scientific connotation of traditional Chinese medicine processing, and enrich the theory of Chinese herbal medicine processing.

  18. The Application of Linear and Nonlinear Water Tanks Case Study in Teaching of Process Control

    NASA Astrophysics Data System (ADS)

    Li, Xiangshun; Li, Zhiang

    2018-02-01

    In the traditional process control teaching, the importance of passing knowledge is emphasized while the development of creative and practical abilities of students is ignored. Traditional teaching methods are not very helpful to breed a good engineer. Case teaching is a very useful way to improve students’ innovative and practical abilities. In the traditional case teaching, knowledge points are taught separately based on different examples or no examples, thus it is very hard to setup the whole knowledge structure. Though all the knowledge is learned, how to use the knowledge to solve engineering problems keeps challenging for students. In this paper, the linear and nonlinear tanks are taken as illustrative examples which involves several knowledge points of process control. The application method of each knowledge point is discussed in detail and simulated. I believe the case-based study will be helpful for students.

  19. Comparing removal of trace organic compounds and assimilable organic carbon (AOC) at advanced and traditional water treatment plants.

    PubMed

    Lou, Jie-Chung; Lin, Chung-Yi; Han, Jia-Yun; Tseng, Wei-Biu; Hsu, Kai-Lin; Chang, Ting-Wei

    2012-06-01

    Stability of drinking water can be indicated by the assimilable organic carbon (AOC). This AOC value represents the regrowth capacity of microorganisms and has large impacts on the quality of drinking water in a distribution system. With respect to the effectiveness of traditional and advanced processing methods in removing trace organic compounds (including TOC, DOC, UV(254), and AOC) from water, experimental results indicate that the removal rate of AOC at the Cheng Ching Lake water treatment plant (which utilizes advanced water treatment processes, and is hereinafter referred to as CCLWTP) is 54%, while the removal rate of AOC at the Gong Yuan water treatment plant (which uses traditional water treatment processes, and is hereinafter referred to as GYWTP) is 36%. In advanced water treatment units, new coagulation-sedimentation processes, rapid filters, and biological activated carbon filters can effectively remove AOC, total organic carbon (TOC), and dissolved organic carbon (DOC). In traditional water treatment units, coagulation-sedimentation processes are most effective in removing AOC. Simulation results and calculations made using the AutoNet method indicate that TOC, TDS, NH(3)-N, and NO(3)-N should be regularly monitored in the CCLWTP, and that TOC, temperature, and NH(3)-N should be regularly monitored in the GYWTP.

  20. Randomized evaluation of a web based interview process for urology resident selection.

    PubMed

    Shah, Satyan K; Arora, Sanjeev; Skipper, Betty; Kalishman, Summers; Timm, T Craig; Smith, Anthony Y

    2012-04-01

    We determined whether a web based interview process for resident selection could effectively replace the traditional on-site interview. For the 2010 to 2011 match cycle, applicants to the University of New Mexico urology residency program were randomized to participate in a web based interview process via Skype or a traditional on-site interview process. Both methods included interviews with the faculty, a tour of facilities and the opportunity to ask current residents any questions. To maintain fairness the applicants were then reinterviewed via the opposite process several weeks later. We assessed comparative effectiveness, cost, convenience and satisfaction using anonymous surveys largely scored on a 5-point Likert scale. Of 39 total participants (33 applicants and 6 faculty) 95% completed the surveys. The web based interview was less costly to applicants (mean $171 vs $364, p=0.05) and required less time away from school (10% missing 1 or more days vs 30%, p=0.04) compared to traditional on-site interview. However, applicants perceived the web based interview process as less effective than traditional on-site interview, with a mean 6-item summative effectiveness score of 21.3 vs 25.6 (p=0.003). Applicants and faculty favored continuing the web based interview process in the future as an adjunct to on-site interviews. Residency interviews can be successfully conducted via the Internet. The web based interview process reduced costs and improved convenience. The findings of this study support the use of videoconferencing as an adjunct to traditional interview methods rather than as a replacement. Copyright © 2012 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  1. The Classification of Tongue Colors with Standardized Acquisition and ICC Profile Correction in Traditional Chinese Medicine

    PubMed Central

    Tu, Li-ping; Chen, Jing-bo; Hu, Xiao-juan; Zhang, Zhi-feng

    2016-01-01

    Background and Goal. The application of digital image processing techniques and machine learning methods in tongue image classification in Traditional Chinese Medicine (TCM) has been widely studied nowadays. However, it is difficult for the outcomes to generalize because of lack of color reproducibility and image standardization. Our study aims at the exploration of tongue colors classification with a standardized tongue image acquisition process and color correction. Methods. Three traditional Chinese medical experts are chosen to identify the selected tongue pictures taken by the TDA-1 tongue imaging device in TIFF format through ICC profile correction. Then we compare the mean value of L * a * b * of different tongue colors and evaluate the effect of the tongue color classification by machine learning methods. Results. The L * a * b * values of the five tongue colors are statistically different. Random forest method has a better performance than SVM in classification. SMOTE algorithm can increase classification accuracy by solving the imbalance of the varied color samples. Conclusions. At the premise of standardized tongue acquisition and color reproduction, preliminary objectification of tongue color classification in Traditional Chinese Medicine (TCM) is feasible. PMID:28050555

  2. The Classification of Tongue Colors with Standardized Acquisition and ICC Profile Correction in Traditional Chinese Medicine.

    PubMed

    Qi, Zhen; Tu, Li-Ping; Chen, Jing-Bo; Hu, Xiao-Juan; Xu, Jia-Tuo; Zhang, Zhi-Feng

    2016-01-01

    Background and Goal . The application of digital image processing techniques and machine learning methods in tongue image classification in Traditional Chinese Medicine (TCM) has been widely studied nowadays. However, it is difficult for the outcomes to generalize because of lack of color reproducibility and image standardization. Our study aims at the exploration of tongue colors classification with a standardized tongue image acquisition process and color correction. Methods . Three traditional Chinese medical experts are chosen to identify the selected tongue pictures taken by the TDA-1 tongue imaging device in TIFF format through ICC profile correction. Then we compare the mean value of L * a * b * of different tongue colors and evaluate the effect of the tongue color classification by machine learning methods. Results . The L * a * b * values of the five tongue colors are statistically different. Random forest method has a better performance than SVM in classification. SMOTE algorithm can increase classification accuracy by solving the imbalance of the varied color samples. Conclusions . At the premise of standardized tongue acquisition and color reproduction, preliminary objectification of tongue color classification in Traditional Chinese Medicine (TCM) is feasible.

  3. Synthesis and characterization of Shanku bhasma-an anti-ulcer herbomineral formulation

    NASA Astrophysics Data System (ADS)

    Rasheed, Shebina P.; Shivashankar, Murugesh

    2017-11-01

    The traditional systems of Medicines are considered as a safer therapy. This context urges the need of Characterization of traditional medicines for their worldwide acceptance and for the safer, efficacious use. Bhasma the traditional Herbo mineral Ayurvedic formulation prepared by bhasmikaran process. Shanka Bhasma is prepared from the shell of a marine organism is a well-known herbo mineral formulation used for the treatment of peptic ulcer. In the present study, shanka bhasma was prepared and its characterization was done by traditional methods and by modern analytical Parameters like IR, X-ray, EDAX TGA and atomic absorption methods. Its antiulcer effect was also evaluated by animal studies.

  4. [Construction of biopharmaceutics classification system of Chinese materia medica].

    PubMed

    Liu, Yang; Wei, Li; Dong, Ling; Zhu, Mei-Ling; Tang, Ming-Min; Zhang, Lei

    2014-12-01

    Based on the characteristics of multicomponent of traditional Chinese medicine and drawing lessons from the concepts, methods and techniques of biopharmaceutics classification system (BCS) in chemical field, this study comes up with the science framework of biopharmaceutics classification system of Chinese materia medica (CMMBCS). Using the different comparison method of multicomponent level and the CMMBCS method of overall traditional Chinese medicine, the study constructs the method process while setting forth academic thoughts and analyzing theory. The basic role of this system is clear to reveal the interaction and the related absorption mechanism of multicomponent in traditional Chinese medicine. It also provides new ideas and methods for improving the quality of Chinese materia medica and the development of new drug research.

  5. Improvement in the traditional processing method and nutritional quality of traditional extruded cassava-based snack (modified Ajogun).

    PubMed

    Obadina, Adewale O; Oyewole, Olusola B; Williams, Oluwasolabomi E

    2013-07-01

    This study was carried out to investigate and improve the traditional processing method and nutritional quality of the traditional cassava snack (Ajogun). Cassava root (Manihot esculenta Crantz L.) of TME 419 variety was processed into mash (40% moisture content). The cassava mash was mixed into different blends to produce fried traditional "Ajogun", fried and baked extrudates (modified Ajogun) as snacks. These products were analyzed to determine the proximate composition including carbohydrate, fat, protein, fiber, ash, and moisture contents and functional properties such as bulk density. The results obtained for the moisture, fat, protein, and ash contents showed significant difference (P < 0.05) between the control sample and the extrudates. However, there was no significant difference (P > 0.05) in the carbohydrate and fiber contents between the three samples. There was no significant difference (P > 0.05) in the bulk density of the snacks. Also, sensory evaluation was carried out on the cassava-based snacks using the 9-point hedonic scale to determine the degree of acceptability. Results obtained showed significant difference (P < 0.05) between the extrudates and control sample in terms of appearance, taste, flavor, color, aroma, texture, and overall acceptability. The highest acceptability level of the product was at 8.04 for the control sample (traditional Ajogun). This study has shown that "Ajogun", which is a lesser known cassava product, is rich in protein and fat.

  6. [Optimization theory and practical application of membrane science technology based on resource of traditional Chinese medicine residue].

    PubMed

    Zhu, Hua-Xu; Duan, Jin-Ao; Guo, Li-Wei; Li, Bo; Lu, Jin; Tang, Yu-Ping; Pan, Lin-Mei

    2014-05-01

    Resource of traditional Chinese medicine residue is an inevitable choice to form new industries characterized of modem, environmental protection and intensive in the Chinese medicine industry. Based on the analysis of source and the main chemical composition of the herb residue, and for the advantages of membrane science and technology used in the pharmaceutical industry, especially membrane separation technology used in improvement technical reserves of traditional extraction and separation process in the pharmaceutical industry, it is proposed that membrane science and technology is one of the most important choices in technological design of traditional Chinese medicine resource industrialization. Traditional Chinese medicine residue is a very complex material system in composition and character, and scientific and effective "separation" process is the key areas of technology to re-use it. Integrated process can improve the productivity of the target product, enhance the purity of the product in the separation process, and solve many tasks which conventional separation is difficult to achieve. As integrated separation technology has the advantages of simplified process and reduced consumption, which are in line with the trend of the modern pharmaceutical industry, the membrane separation technology can provide a broad platform for integrated process, and membrane separation technology with its integrated technology have broad application prospects in achieving resource and industrialization process of traditional Chinese medicine residue. We discuss the principles, methods and applications practice of effective component resources in herb residue using membrane separation and integrated technology, describe the extraction, separation, concentration and purification application of membrane technology in traditional Chinese medicine residue, and systematically discourse suitability and feasibility of membrane technology in the process of traditional Chinese medicine resource industrialization in this paper.

  7. Beyond the standard plate count: genomic views into microbial food ecology

    USDA-ARS?s Scientific Manuscript database

    Food spoilage is a complex process that involves multiple species with specific niches and metabolic processes; bacterial culturing techniques are the traditional methods for identifying the microbes responsible. These culture-dependent methods may be considered selective, targeting the isolation of...

  8. The comparison of two methods to manufacture fused biconical tapered optical fiber coupler

    NASA Astrophysics Data System (ADS)

    Wang, Yue; Liu, Hairong

    2009-08-01

    Optical fiber coupler is a directional coupler which is crucial component for optical fiber communication systems. The fused biconical taper is the most important method in facture of optical fiber coupler, with many advantages of low excess loss, precise coupling ratio, good consistency and stability. In this paper we have introduced a new method to manufacture optical fiber coupler. And more over the new manufacture process has been compared with the traditional manufacture method. In the traditional crafts, two optical fibers are parallel placed, and then use the method of tie a knot of the two optical fibers. In the new process, a new program of fiber placement is introduced. Two optical fibers are parallel placed in the middle of the fixture, and then in order to make the bare part of the optical fiber close as much as possible, the new plan using high temperature resistant material bind the both end of the fiber which are not removing the cladding. After many contrast tests, we can see that adopt the improved method of fiber placement, during the process of fiber pulling, the variation of optical power in the directional arm and the coupler arm are more smooth and steady. But the excess loss (EL) generated in the process of pulling is a bit higher than the traditional method of tie a knot. The tests show that the new method of optical fiber placement is feasible in the actual projects for the manufacture of coupler with low coupling ratio, but for the control of the EL still need further studying.

  9. Bridging the clinician/researcher gap with systemic research: the case for process research, dyadic, and sequential analysis.

    PubMed

    Oka, Megan; Whiting, Jason

    2013-01-01

    In Marriage and Family Therapy (MFT), as in many clinical disciplines, concern surfaces about the clinician/researcher gap. This gap includes a lack of accessible, practical research for clinicians. MFT clinical research often borrows from the medical tradition of randomized control trials, which typically use linear methods, or follow procedures distanced from "real-world" therapy. We review traditional research methods and their use in MFT and propose increased use of methods that are more systemic in nature and more applicable to MFTs: process research, dyadic data analysis, and sequential analysis. We will review current research employing these methods, as well as suggestions and directions for further research. © 2013 American Association for Marriage and Family Therapy.

  10. DNA Barcoding for the Identification and Authentication of Animal Species in Traditional Medicine.

    PubMed

    Yang, Fan; Ding, Fei; Chen, Hong; He, Mingqi; Zhu, Shixin; Ma, Xin; Jiang, Li; Li, Haifeng

    2018-01-01

    Animal-based traditional medicine not only plays a significant role in therapeutic practices worldwide but also provides a potential compound library for drug discovery. However, persistent hunting and illegal trade markedly threaten numerous medicinal animal species, and increasing demand further provokes the emergence of various adulterants. As the conventional methods are difficult and time-consuming to detect processed products or identify animal species with similar morphology, developing novel authentication methods for animal-based traditional medicine represents an urgent need. During the last decade, DNA barcoding offers an accurate and efficient strategy that can identify existing species and discover unknown species via analysis of sequence variation in a standardized region of DNA. Recent studies have shown that DNA barcoding as well as minibarcoding and metabarcoding is capable of identifying animal species and discriminating the authentics from the adulterants in various types of traditional medicines, including raw materials, processed products, and complex preparations. These techniques can also be used to detect the unlabelled and threatened animal species in traditional medicine. Here, we review the recent progress of DNA barcoding for the identification and authentication of animal species used in traditional medicine, which provides a reference for quality control and trade supervision of animal-based traditional medicine.

  11. DNA Barcoding for the Identification and Authentication of Animal Species in Traditional Medicine

    PubMed Central

    Yang, Fan; Ding, Fei; Chen, Hong; He, Mingqi; Zhu, Shixin; Ma, Xin; Jiang, Li

    2018-01-01

    Animal-based traditional medicine not only plays a significant role in therapeutic practices worldwide but also provides a potential compound library for drug discovery. However, persistent hunting and illegal trade markedly threaten numerous medicinal animal species, and increasing demand further provokes the emergence of various adulterants. As the conventional methods are difficult and time-consuming to detect processed products or identify animal species with similar morphology, developing novel authentication methods for animal-based traditional medicine represents an urgent need. During the last decade, DNA barcoding offers an accurate and efficient strategy that can identify existing species and discover unknown species via analysis of sequence variation in a standardized region of DNA. Recent studies have shown that DNA barcoding as well as minibarcoding and metabarcoding is capable of identifying animal species and discriminating the authentics from the adulterants in various types of traditional medicines, including raw materials, processed products, and complex preparations. These techniques can also be used to detect the unlabelled and threatened animal species in traditional medicine. Here, we review the recent progress of DNA barcoding for the identification and authentication of animal species used in traditional medicine, which provides a reference for quality control and trade supervision of animal-based traditional medicine. PMID:29849709

  12. [Effect and regulation of drying on quality of traditional Chinese medicine pills].

    PubMed

    Qi, Ya-Ru; Li, Yuan-Hui; Han, Li; Wu, Zhen-Feng; Yue, Peng-Fei; Wang, Xue-Cheng; Xiong, Yao-Kun; Yang, Ming

    2017-06-01

    The dry quality of traditional Chinese medicine pills is the hot spot of pills research, because their quality has a crucial effect on the efficacy and development of dosage forms. Through literature research and statistical analysis, we would review the current problems on the drying of traditional Chinese medicine pills in this paper, and surrounding the evaluation system for traditional Chinese medicine pills, analyze the characteristics of common drying equipment and processes as well as their effect on quality of pills, discuss the problems in drying equipment and process as well as quality, and put forward the corresponding strategies, hoping to provide new ideas and new methods for the quality improvement of traditional Chinese medicine pills and quality standards. Copyright© by the Chinese Pharmaceutical Association.

  13. [Sulfur dioxide limit standard and residues in Chinese medicinal materials].

    PubMed

    Kang, Chuan-Zhi; Yang, Wan-Zhen; Mo, Ge; Zhou, Li; Jiang, Jing-Yi; Lv, Chao-Geng; Wang, Sheng; Zhou, Tao; Yang, Ye; Guo, Lan-Ping

    2018-01-01

    The traditional sulfur fumigation processing method has been widely used in the initial processing and storage of traditional Chinese medicinal materials due to its economy, efficiency, convenience, high operability and effect on mold and insect prevention. However, excessive sulfur fumigation of traditional Chinese medicinal materials would lead to the changes in chemical compositions, and even endanger human health. This study showed that traditional Chinese medicinal materials were sulfur fumigated directly after being harvested for quick drying, or fumigated after being weted in the storage process for preventing mold and insects. We found that the sulfur dioxide limits for traditional Chinese medicinal materials were stricter than those for foods. Based on the existing limit standards, we obtained the data of sulfur dioxide residues for 35 types of traditional Chinese medicinal materials in a total of 862 batches. According to the limit standard in the Chinese Pharmacopoeia (150, 400 mg·kg⁻¹), the average over-standard rate of sulfur dioxide was as high as 52.43%, but it was reduced to 29.47% if calculated based on the limit for vegetable additive standard (500 mg·kg⁻¹). Sulfur fumigation issue shall be considered correctly: sulfur dioxide is a type of low toxic substance and less dangerous than aflatoxin and other highly toxic substances, and a small amount of residue would not increase the toxicity of traditional Chinese medicinal materials. However, sulfur fumigation might change the content of chemical substances and affect the quality of traditional Chinese medicinal materials. Furthermore, the exposure hazards of toxic substances are comprehensively correlated with exposure cycle, exposure frequency, and application method. In conclusion, it is suggested to strengthen the studies on the limit standard of traditional Chinese medicinal materials, formulate practical and feasible limit standard for sulfur dioxide residues in traditional Chinese medicinal materials that are consistent with the medication characteristics of traditional Chinese medicinal materials and can guarantee people's demand for safe medication. Copyright© by the Chinese Pharmaceutical Association.

  14. Comparison of an automated Most Probable Number (MPN) technique to traditional plating methods for estimating populations of total aerobes, coliforms and E. coli associated with freshly processed broiler chickens

    USDA-ARS?s Scientific Manuscript database

    Recently, an instrument (TEMPOTM) has been developed to automate the Most Probable Number (MPN) technique and reduce the effort required to estimate some bacterial populations. We compared the automated MPN technique to traditional microbiological plating methods or PetrifilmTM for estimating the t...

  15. Establishment of one-step approach to detoxification of hypertoxic aconite based on the evaluation of alkaloids contents and quality.

    PubMed

    Zhang, Ding-Kun; Han, Xue; Tan, Peng; Li, Rui-Yu; Niu, Ming; Zhang, Cong-En; Wang, Jia-Bo; Yang, Ming; Xiao, Xiao-He

    2017-01-01

    Aconite is a valuable drug and also a toxic material, which can be used only after detoxification processing. Although traditional processing methods can achieve detoxification effect as desired, there are some obvious drawbacks, including a significant loss of alkaloids and poor quality consistency. It is thus necessary to develop a new detoxification approach. In the present study, we designed a novel one-step detoxification approach by quickly drying fresh-cut aconite particles. In order to evaluate the technical advantages, the contents of mesaconitine, aconitine, hypaconitine, benzoylmesaconine, benzoylaconine, benzoylhypaconine, neoline, fuziline, songorine, and talatisamine were determined using HPLC and UHPLC/Q-TOF-MS. Multivariate analysis methods, such as Clustering analysis and Principle component analysis, were applied to determine the quality differences between samples. Our results showed that traditional processes could reduce toxicity as desired, but also led to more than 85.2% alkaloids loss. However, our novel one-step method was capable of achieving virtually the same detoxification effect, with only an approximately 30% alkaloids loss. Cluster analysis and Principal component analysis analyses suggested that Shengfupian and the novel products were significantly different from various traditional products. Acute toxicity testing showed that the novel products achieved a good detoxification effect, with its maximum tolerated dose being equivalent to 20 times of adult dosage. And cardiac effect testing also showed that the activity of the novel products was stronger than that of traditional products. Moreover, particles specification greatly improved the quality consistency of the novel products, which was immensely superior to the traditional products. These results would help guide the rational optimization of aconite processing technologies, providing better drugs for clinical treatment. Copyright © 2017 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.

  16. Aconitum in traditional Chinese medicine: a valuable drug or an unpredictable risk?

    PubMed

    Singhuber, Judith; Zhu, Ming; Prinz, Sonja; Kopp, Brigitte

    2009-10-29

    Aconitum species have been used in China as an essential drug in Traditional Chinese Medicine (TCM) for 2000 years. Reviewing the clinical application of Aconitum, their pharmacological effects, toxicity and detoxifying measures, herb-herb interactions, clinical taboos, famous herbal formulas, traditional and current herbal processing methods based upon a wide range of literature investigations serve as a case study to explore the multidisciplinary implications of botanicals used in TCM. The toxicological risk of improper usage of Aconitum remains very high, especially in countries like China, India and Japan. The toxicity of Aconitum mainly derives from the diester diterpene alkaloids (DDAs) including aconitine (AC), mesaconitine (MA) and hypaconitine (HA). They can be decomposed into less or non-toxic derivatives through Chinese traditional processing methods (Paozhi), which play an essential role in detoxification. Using Paozhi, the three main forms of processed aconite -- yanfuzi, heishunpian and baifupian -- can be obtained (CPCommission, 2005). Moreover, some new processing techniques have been developed in China such as pressure-steaming. The current development of fingerprint assays, in particular HPLC, has set a good basis to conduct an appropriate quality control for TCM crude herbs and their ready-made products. Therefore, a stipulation for a maximum level of DDA content of Aconitum is highly desirable in order to guarantee the clinical safety and its low toxicity in decoctions. Newly developed HPLC methods have made the accurate and simultaneous determination and quantification of DDA content interesting.

  17. Automated Cellient(™) cytoblocks: better, stronger, faster?

    PubMed

    Prendeville, S; Brosnan, T; Browne, T J; McCarthy, J

    2014-12-01

    Cytoblocks (CBs), or cell blocks, provide additional morphological detail and a platform for immunocytochemistry (ICC) in cytopathology. The Cellient(™) system produces CBs in 45 minutes using methanol fixation, compared with traditional CBs, which require overnight formalin fixation. This study compares Cellient and traditional CB methods in terms of cellularity, morphology and immunoreactivity, evaluates the potential to add formalin fixation to the Cellient method for ICC studies and determines the optimal sectioning depth for maximal cellularity in Cellient CBs. One hundred and sixty CBs were prepared from 40 cytology samples (32 malignant, eight benign) using four processing methods: (A) traditional; (B) Cellient (methanol fixation); (C) Cellient using additional formalin fixation for 30 minutes; (D) Cellient using additional formalin fixation for 60 minutes. Haematoxylin and eosin-stained sections were assessed for cellularity and morphology. ICC was assessed on 14 cases with a panel of antibodies. Three additional Cellient samples were serially sectioned to determine the optimal sectioning depth. Scoring was performed by two independent, blinded reviewers. For malignant cases, morphology was superior with Cellient relative to traditional CBs (P < 0.001). Cellularity was comparable across all methods. ICC was excellent in all groups and the addition of formalin at any stage during the Cellient process did not influence the staining quality. Serial sectioning through Cellient CBs showed optimum cellularity at 30-40 μm with at least 27 sections obtainable. Cellient CBs provide superior morphology to traditional CBs and, if required, formalin fixation may be added to the Cellient process for ICC. Optimal Cellient CB cellularity is achieved at 30-40 μm, which will impact on the handling of cases in daily practice. © 2014 John Wiley & Sons Ltd.

  18. Optimized Laplacian image sharpening algorithm based on graphic processing unit

    NASA Astrophysics Data System (ADS)

    Ma, Tinghuai; Li, Lu; Ji, Sai; Wang, Xin; Tian, Yuan; Al-Dhelaan, Abdullah; Al-Rodhaan, Mznah

    2014-12-01

    In classical Laplacian image sharpening, all pixels are processed one by one, which leads to large amount of computation. Traditional Laplacian sharpening processed on CPU is considerably time-consuming especially for those large pictures. In this paper, we propose a parallel implementation of Laplacian sharpening based on Compute Unified Device Architecture (CUDA), which is a computing platform of Graphic Processing Units (GPU), and analyze the impact of picture size on performance and the relationship between the processing time of between data transfer time and parallel computing time. Further, according to different features of different memory, an improved scheme of our method is developed, which exploits shared memory in GPU instead of global memory and further increases the efficiency. Experimental results prove that two novel algorithms outperform traditional consequentially method based on OpenCV in the aspect of computing speed.

  19. Study on algorithm of process neural network for soft sensing in sewage disposal system

    NASA Astrophysics Data System (ADS)

    Liu, Zaiwen; Xue, Hong; Wang, Xiaoyi; Yang, Bin; Lu, Siying

    2006-11-01

    A new method of soft sensing based on process neural network (PNN) for sewage disposal system is represented in the paper. PNN is an extension of traditional neural network, in which the inputs and outputs are time-variation. An aggregation operator is introduced to process neuron, and it makes the neuron network has the ability to deal with the information of space-time two dimensions at the same time, so the data processing enginery of biological neuron is imitated better than traditional neuron. Process neural network with the structure of three layers in which hidden layer is process neuron and input and output are common neurons for soft sensing is discussed. The intelligent soft sensing based on PNN may be used to fulfill measurement of the effluent BOD (Biochemical Oxygen Demand) from sewage disposal system, and a good training result of soft sensing was obtained by the method.

  20. Parameter prediction based on Improved Process neural network and ARMA error compensation in Evaporation Process

    NASA Astrophysics Data System (ADS)

    Qian, Xiaoshan

    2018-01-01

    The traditional model of evaporation process parameters have continuity and cumulative characteristics of the prediction error larger issues, based on the basis of the process proposed an adaptive particle swarm neural network forecasting method parameters established on the autoregressive moving average (ARMA) error correction procedure compensated prediction model to predict the results of the neural network to improve prediction accuracy. Taking a alumina plant evaporation process to analyze production data validation, and compared with the traditional model, the new model prediction accuracy greatly improved, can be used to predict the dynamic process of evaporation of sodium aluminate solution components.

  1. Study on process evaluation model of students' learning in practical course

    NASA Astrophysics Data System (ADS)

    Huang, Jie; Liang, Pei; Shen, Wei-min; Ye, Youxiang

    2017-08-01

    In practical course teaching based on project object method, the traditional evaluation methods include class attendance, assignments and exams fails to give incentives to undergraduate students to learn innovatively and autonomously. In this paper, the element such as creative innovation, teamwork, document and reporting were put into process evaluation methods, and a process evaluation model was set up. Educational practice shows that the evaluation model makes process evaluation of students' learning more comprehensive, accurate, and fairly.

  2. Improvement in the traditional processing method and nutritional quality of traditional extruded cassava-based snack (modified Ajogun)

    PubMed Central

    Obadina, Adewale O; Oyewole, Olusola B; Williams, Oluwasolabomi E

    2013-01-01

    This study was carried out to investigate and improve the traditional processing method and nutritional quality of the traditional cassava snack (Ajogun). Cassava root (Manihot esculenta Crantz L.) of TME 419 variety was processed into mash (40% moisture content). The cassava mash was mixed into different blends to produce fried traditional “Ajogun”, fried and baked extrudates (modified Ajogun) as snacks. These products were analyzed to determine the proximate composition including carbohydrate, fat, protein, fiber, ash, and moisture contents and functional properties such as bulk density. The results obtained for the moisture, fat, protein, and ash contents showed significant difference (P < 0.05) between the control sample and the extrudates. However, there was no significant difference (P > 0.05) in the carbohydrate and fiber contents between the three samples. There was no significant difference (P > 0.05) in the bulk density of the snacks. Also, sensory evaluation was carried out on the cassava-based snacks using the 9-point hedonic scale to determine the degree of acceptability. Results obtained showed significant difference (P < 0.05) between the extrudates and control sample in terms of appearance, taste, flavor, color, aroma, texture, and overall acceptability. The highest acceptability level of the product was at 8.04 for the control sample (traditional Ajogun). This study has shown that “Ajogun”, which is a lesser known cassava product, is rich in protein and fat. PMID:24804039

  3. [Contention on the theory of processing techniques of Chinese materia medica in the Ming-Qing period].

    PubMed

    Chen, Bin; Jia, Tianzhu

    2015-03-01

    On the basis of the golden stage of development of processing techniques of medicinals in the Song dynasty, the theory and techniques of processing in the Ming-Qing dynasties developed and accomplished further. The knowledge of some physicians on the processing of common medicinal, such as Radix rehmannia and Radixophiopogonis, was questioned, with new idea of processing methods put forward and argued against those insisting traditional ones, marking the progress of the art of processing. By reviewing the contention of technical theory of medicinal processing in the Ming-Qing period, useful references can be provided for the inheritance and development of the traditional art of processing medicinals.

  4. Finite Element Analysis in Concurrent Processing: Computational Issues

    NASA Technical Reports Server (NTRS)

    Sobieszczanski-Sobieski, Jaroslaw; Watson, Brian; Vanderplaats, Garrett

    2004-01-01

    The purpose of this research is to investigate the potential application of new methods for solving large-scale static structural problems on concurrent computers. It is well known that traditional single-processor computational speed will be limited by inherent physical limits. The only path to achieve higher computational speeds lies through concurrent processing. Traditional factorization solution methods for sparse matrices are ill suited for concurrent processing because the null entries get filled, leading to high communication and memory requirements. The research reported herein investigates alternatives to factorization that promise a greater potential to achieve high concurrent computing efficiency. Two methods, and their variants, based on direct energy minimization are studied: a) minimization of the strain energy using the displacement method formulation; b) constrained minimization of the complementary strain energy using the force method formulation. Initial results indicated that in the context of the direct energy minimization the displacement formulation experienced convergence and accuracy difficulties while the force formulation showed promising potential.

  5. Effect of processing methods on the stability and nutritional profiles of navy bean-soybean emulsions

    USDA-ARS?s Scientific Manuscript database

    In this study, an innovative emulsion made from soybean and navy bean blends of different proportionalities was developed. In addition, two processing methods were evaluated: traditional cooking and jet-cooking. The physical attributes and storage stability were measured and compared. This study fou...

  6. The classification and application of toxic Chinese materia medica.

    PubMed

    Liu, Xinmin; Wang, Qiong; Song, Guangqing; Zhang, Guangping; Ye, Zuguang; Williamson, Elizabeth M

    2014-03-01

    Many important drugs in the Chinese materia medica (CMM) are known to be toxic, and it has long been recognized in classical Chinese medical theory that toxicity can arise directly from the components of a single CMM or may be induced by an interaction between combined CMM. Traditional Chinese Medicine presents a unique set of pharmaceutical theories that include particular methods for processing, combining and decocting, and these techniques contribute to reducing toxicity as well as enhancing efficacy. The current classification of toxic CMM drugs, traditional methods for processing toxic CMM and the prohibited use of certain combinations, is based on traditional experience and ancient texts and monographs, but accumulating evidence increasingly supports their use to eliminate or reduce toxicity. Modern methods are now being used to evaluate the safety of CMM; however, a new system for describing the toxicity of Chinese herbal medicines may need to be established to take into account those herbs whose toxicity is delayed or otherwise hidden, and which have not been incorporated into the traditional classification. This review explains the existing classification and justifies it where appropriate, using experimental results often originally published in Chinese and previously not available outside China. Copyright © 2013 John Wiley & Sons, Ltd.

  7. Traditional coping strategies and disaster response: examples from the South Pacific region.

    PubMed

    Fletcher, Stephanie M; Thiessen, Jodi; Gero, Anna; Rumsey, Michele; Kuruppu, Natasha; Willetts, Juliet

    2013-01-01

    The Pacific Islands are vulnerable to climate change and increased risk of disasters not only because of their isolated and often low lying geographical setting but because of their economic status which renders them reliant on donor support. In a qualitative study exploring the adaptive capacity of Pacific Island Countries (PICs) across four countries, Cook Islands, Fiji, Samoa, and Vanuatu, it was clear that traditional coping strategies are consistently being applied as part of response to disasters and climate changes. This paper describes five common strategies employed in PICs as understood through this research: recognition of traditional methods; faith and religious beliefs; traditional governance and leadership; family and community involvement; and agriculture and food security. While this study does not trial the efficacy of these methods, it provides an indication of what methods are being used and therefore a starting point for further research into which of these traditional strategies are beneficial. These findings also provide important impetus for Pacific Island governments to recognise traditional approaches in their disaster preparedness and response processes.

  8. Traditional Coping Strategies and Disaster Response: Examples from the South Pacific Region

    PubMed Central

    Fletcher, Stephanie M.; Kuruppu, Natasha

    2013-01-01

    The Pacific Islands are vulnerable to climate change and increased risk of disasters not only because of their isolated and often low lying geographical setting but because of their economic status which renders them reliant on donor support. In a qualitative study exploring the adaptive capacity of Pacific Island Countries (PICs) across four countries, Cook Islands, Fiji, Samoa, and Vanuatu, it was clear that traditional coping strategies are consistently being applied as part of response to disasters and climate changes. This paper describes five common strategies employed in PICs as understood through this research: recognition of traditional methods; faith and religious beliefs; traditional governance and leadership; family and community involvement; and agriculture and food security. While this study does not trial the efficacy of these methods, it provides an indication of what methods are being used and therefore a starting point for further research into which of these traditional strategies are beneficial. These findings also provide important impetus for Pacific Island governments to recognise traditional approaches in their disaster preparedness and response processes. PMID:24454413

  9. Cults and Satanism: Threats to Teens. A "Bulletin" Special.

    ERIC Educational Resources Information Center

    Rudin, Marcia R.

    1990-01-01

    Administrators, teachers, and counselors must learn to recognize the signs of cult or Satanic-influenced youngsters. The process and effects of mind-control are unique and cannot be understood in traditional psychiatric terms or treated by traditional therapeutic methods. Schools should hold preventive cult-education programs. The International…

  10. How to Use TCM Informatics to Study Traditional Chinese Medicine in Big Data Age.

    PubMed

    Shi, Cheng; Gong, Qing-Yue; Zhou, Jinhai

    2017-01-01

    This paper introduces the characteristics and complexity of traditional Chinese medicine (TCM) data, considers that modern big data processing technology has brought new opportunities for the research of TCM, and gives some ideas and methods to apply big data technology in TCM.

  11. Teaching Methods Influencing the Sustainability of the Teaching Process in Technology Education in General Education Schools

    ERIC Educational Resources Information Center

    Soobik, Mart

    2014-01-01

    The sustainability of technology education is related to a traditional understanding of craft and the methods used to teach it; however, the methods used in the teaching process have been influenced by the innovative changes accompanying the development of technology. In respect to social and economic development, it is important to prepare young…

  12. [Establishment of design space for production process of traditional Chinese medicine preparation].

    PubMed

    Xu, Bing; Shi, Xin-Yuan; Qiao, Yan-Jiang; Wu, Zhi-Sheng; Lin, Zhao-Zhou

    2013-03-01

    The philosophy of quality by design (QbD) is now leading the changes in the drug manufacturing mode from the conventional test-based approach to the science and risk based approach focusing on the detailed research and understanding of the production process. Along with the constant deepening of the understanding of the manufacturing process, the design space will be determined, and the emphasis of quality control will be shifted from the quality standards to the design space. Therefore, the establishment of the design space is core step in the implementation of QbD, and it is of great importance to study the methods for building the design space. This essay proposes the concept of design space for the production process of traditional Chinese medicine (TCM) preparations, gives a systematic introduction of the concept of the design space, analyzes the feasibility and significance to build the design space in the production process of traditional Chinese medicine preparations, and proposes study approaches on the basis of examples that comply with the characteristics of traditional Chinese medicine preparations, as well as future study orientations.

  13. A Novel Residual Frequency Estimation Method for GNSS Receivers.

    PubMed

    Nguyen, Tu Thi-Thanh; La, Vinh The; Ta, Tung Hai

    2018-01-04

    In Global Navigation Satellite System (GNSS) receivers, residual frequency estimation methods are traditionally applied in the synchronization block to reduce the transient time from acquisition to tracking, or they are used within the frequency estimator to improve its accuracy in open-loop architectures. There are several disadvantages in the current estimation methods, including sensitivity to noise and wide search space size. This paper proposes a new residual frequency estimation method depending on differential processing. Although the complexity of the proposed method is higher than the one of traditional methods, it can lead to more accurate estimates, without increasing the size of the search space.

  14. Manufacture of ultra high precision aerostatic bearings based on glass guide

    NASA Astrophysics Data System (ADS)

    Guo, Meng; Dai, Yifan; Peng, Xiaoqiang; Tie, Guipeng; Lai, Tao

    2017-10-01

    The aerostatic guide in the traditional three-coordinate measuring machine and profilometer generally use metal or ceramics material. Limited by the guide processing precision, the measurement accuracy of these traditional instruments is around micro-meter level. By selection of optical materials as guide material, optical processing method and laser interference measurement can be introduced to the traditional aerostatic bearings manufacturing field. By using the large aperture wave-front interference measuring equipment , the shape and position error of the glass guide can be obtained in high accuracy and then it can be processed to 0.1μm or even better with the aid of Magnetorheological Finishing(MRF) and Computer Controlled Optical Surfacing (CCOS) process and other modern optical processing method, so the accuracy of aerostatic bearings can be fundamentally improved and ultra high precision coordinate measuring can be achieved. This paper introduces the fabrication and measurement process of the glass guide by K9 with 300mm measuring range, and its working surface accuracy is up to 0.1μm PV, the verticality and parallelism error between the two guide rail face is better than 2μm, and the straightness of the aerostatic bearings by this K9 glass guide is up to 40nm after error compensation.

  15. The use of computational inspection to identify process window limiting hotspots and predict sub-15nm defects with high capture rate

    NASA Astrophysics Data System (ADS)

    Ham, Boo-Hyun; Kim, Il-Hwan; Park, Sung-Sik; Yeo, Sun-Young; Kim, Sang-Jin; Park, Dong-Woon; Park, Joon-Soo; Ryu, Chang-Hoon; Son, Bo-Kyeong; Hwang, Kyung-Bae; Shin, Jae-Min; Shin, Jangho; Park, Ki-Yeop; Park, Sean; Liu, Lei; Tien, Ming-Chun; Nachtwein, Angelique; Jochemsen, Marinus; Yan, Philip; Hu, Vincent; Jones, Christopher

    2017-03-01

    As critical dimensions for advanced two dimensional (2D) DUV patterning continue to shrink, the exact process window becomes increasingly difficult to determine. The defect size criteria shrink with the patterning critical dimensions and are well below the resolution of current optical inspection tools. As a result, it is more challenging for traditional bright field inspection tools to accurately discover the hotspots that define the process window. In this study, we use a novel computational inspection method to identify the depth-of-focus limiting features of a 10 nm node mask with 2D metal structures (single exposure) and compare the results to those obtained with a traditional process windows qualification (PWQ) method based on utilizing a focus modulated wafer and bright field inspection (BFI) to detect hotspot defects. The method is extended to litho-etch litho-etch (LELE) on a different test vehicle to show that overlay related bridging hotspots also can be identified.

  16. A Multilevel Comprehensive Assessment of International Accreditation for Business Programmes-Based on AMBA Accreditation of GDUFS

    ERIC Educational Resources Information Center

    Jiang, Yong

    2017-01-01

    Traditional mathematical methods built around exactitude have limitations when applied to the processing of educational information, due to their uncertainty and imperfection. Alternative mathematical methods, such as grey system theory, have been widely applied in processing incomplete information systems and have proven effective in a number of…

  17. Phytoforensics—Using trees to find contamination

    USGS Publications Warehouse

    Wilson, Jordan L.

    2017-09-28

    The water we drink, air we breathe, and soil we come into contact with have the potential to adversely affect our health because of contaminants in the environment. Environmental samples can characterize the extent of potential contamination, but traditional methods for collecting water, air, and soil samples below the ground (for example, well drilling or direct-push soil sampling) are expensive and time consuming. Trees are closely connected to the subsurface and sampling tree trunks can indicate subsurface pollutants, a process called phytoforensics. Scientists at the Missouri Water Science Center were among the first to use phytoforensics to screen sites for contamination before using traditional sampling methods, to guide additional sampling, and to show the large cost savings associated with tree sampling compared to traditional methods. 

  18. On eco-efficient technologies to minimize industrial water consumption

    NASA Astrophysics Data System (ADS)

    Amiri, Mohammad C.; Mohammadifard, Hossein; Ghaffari, Ghasem

    2016-07-01

    Purpose - Water scarcity will further stress on available water systems and decrease the security of water in many areas. Therefore, innovative methods to minimize industrial water usage and waste production are of paramount importance in the process of extending fresh water resources and happen to be the main life support systems in many arid regions of the world. This paper demonstrates that there are good opportunities for many industries to save water and decrease waste water in softening process by substituting traditional with echo-friendly methods. The patented puffing method is an eco-efficient and viable technology for water saving and waste reduction in lime softening process. Design/methodology/approach - Lime softening process (LSP) is a very sensitive process to chemical reactions. In addition, optimal monitoring not only results in minimizing sludge that must be disposed of but also it reduces the operating costs of water conditioning. Weakness of the current (regular) control of LSP based on chemical analysis has been demonstrated experimentally and compared with the eco-efficient puffing method. Findings - This paper demonstrates that there is a good opportunity for many industries to save water and decrease waste water in softening process by substituting traditional method with puffing method, a patented eco-efficient technology. Originality/value - Details of the required innovative works to minimize industrial water usage and waste production are outlined in this paper. Employing the novel puffing method for monitoring of lime softening process results in saving a considerable amount of water while reducing chemical sludge.

  19. Application of Ozone MBBR Process in Refinery Wastewater Treatment

    NASA Astrophysics Data System (ADS)

    Lin, Wang

    2018-01-01

    Moving Bed Biofilm Reactor (MBBR) is a kind of sewage treatment technology based on fluidized bed. At the same time, it can also be regarded as an efficient new reactor between active sludge method and the biological membrane method. The application of ozone MBBR process in refinery wastewater treatment is mainly studied. The key point is to design the ozone +MBBR combined process based on MBBR process. The ozone +MBBR process is used to analyze the treatment of concentrated water COD discharged from the refinery wastewater treatment plant. The experimental results show that the average removal rate of COD is 46.0%~67.3% in the treatment of reverse osmosis concentrated water by ozone MBBR process, and the effluent can meet the relevant standard requirements. Compared with the traditional process, the ozone MBBR process is more flexible. The investment of this process is mainly ozone generator, blower and so on. The prices of these items are relatively inexpensive, and these costs can be offset by the excess investment in traditional activated sludge processes. At the same time, ozone MBBR process has obvious advantages in water quality, stability and other aspects.

  20. FEM-based strain analysis study for multilayer sheet forming process

    NASA Astrophysics Data System (ADS)

    Zhang, Rongjing; Lang, Lihui; Zafar, Rizwan

    2015-12-01

    Fiber metal laminates have many advantages over traditional laminates (e.g., any type of fiber and resin material can be placed anywhere between the metallic layers without risk of failure of the composite fabric sheets). Furthermore, the process requirements to strictly control the temperature and punch force in fiber metal laminates are also less stringent than those in traditional laminates. To further explore the novel method, this study conducts a finite element method-based (FEM-based) strain analysis on multilayer blanks by using the 3A method. Different forming modes such as wrinkling and fracture are discussed by using experimental and numerical studies. Hydroforming is used for multilayer forming. The Barlat 2000 yield criteria and DYNAFORM/LS-DYNA are used for the simulations. Optimal process parameters are determined on the basis of fixed die-binder gap and variable cavity pressure. The results of this study will enhance the knowledge on the mechanics of multilayer structures formed by using the 3A method and expand its commercial applications.

  1. Comparing Traditional versus Alternative Sequencing of Instruction When Using Simulation Modeling

    ERIC Educational Resources Information Center

    Bowen, Bradley; DeLuca, William

    2015-01-01

    Many engineering and technology education classrooms incorporate simulation modeling as part of curricula to teach engineering and STEM-based concepts. The traditional method of the learning process has students first learn the content from the classroom teacher and then may have the opportunity to apply the learned content through simulation…

  2. [Study on two preparation methods for beta-CD inclusion compound of four traditional Chinese medicine volatile oils].

    PubMed

    Li, Hailiang; Cui, Xiaoli; Tong, Yan; Gong, Muxin

    2012-04-01

    To compare inclusion effects and process conditions of two preparation methods-colloid mill and saturated solution-for beta-CD inclusion compound of four traditional Chinese medicine volatile oils and study the relationship between each process condition and volatile oil physical properties and the regularity of selective inclusion of volatile oil components. Volatile oils from Nardostachyos Radix et Rhizoma, Amomi Fructus, Zingiberis Rhizoma and Angelicaesinensis Radix were prepared using two methods in the orthogonal test. These inclusion compounds by optimized processes were assessed and compared by such methods as TLC, IR and scanning electron microscope. Inclusion oils were extracted by steam distillation, and the components found before and after inclusion were analyzed by GC-MS. Analysis showed that new inclusion compounds, but inclusion compounds prepared by the two processes had differences to some extent. The colloid mill method showed a better inclusion effect than the saturated solution method, indicating that their process conditions had relations with volatile oil physical properties. There were differences in the inclusion selectivity of components between each other. The colloid mill method for inclusion preparation is more suitable for industrial requirements. To prepare volatile oil inclusion compounds with heavy gravity and high refractive index, the colloid mill method needs longer time and more water, while the saturated solution method requires higher temperature and more beta-cyclodextrin. The inclusion complex prepared with the colloid mill method contains extended molecular weight chemical composition, but the kinds of components are reduced.

  3. Developing a Phonological Awareness Curriculum: Reflections on an Implementation Science Framework

    ERIC Educational Resources Information Center

    Goldstein, Howard; Olszewski, Arnold

    2015-01-01

    Purpose: This article describes the process of developing and implementing a supplemental early literacy curriculum designed for preschoolers demonstrating delays in literacy development. Method: Intervention research and implementation research have traditionally been viewed as sequential processes. This article illustrates a process of…

  4. Evaluation of MALDI-TOF mass spectrometry for differentiation of Pichia kluyveri strains isolated from traditional fermentation processes.

    PubMed

    De la Torre González, Francisco Javier; Gutiérrez Avendaño, Daniel Oswaldo; Gschaedler Mathis, Anne Christine; Kirchmayr, Manuel Reinhart

    2018-06-06

    Non- Saccharomyces yeasts are widespread microorganisms and some time ago were considered contaminants in the beverage industry. However, nowadays they have gained importance for their ability to produce aromatic compounds, which in alcoholic beverages improves aromatic complexity and therefore the overall quality. Thus, identification and differentiation of the species involved in fermentation processes is vital and can be classified in traditional methods and techniques based on molecular biology. Traditional methods, however, can be expensive, laborious and/or unable to accurately discriminate on strain level. In the present study, a total of 19 strains of Pichia kluyveri isolated from mezcal, tejuino and cacao fermentations were analyzed with rep-PCR fingerprinting and matrix assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). The comparative analysis between MS spectra and rep-PCR patterns obtained from these strains showed a high similarity between both methods. However, minimal differences between the obtained rep-PCR and MALDI-TOF MS clusters could be observed. The data shown suggests that MALDI-TOF MS is a promising alternative technique for rapid, reliable and cost-effective differentiation of natives yeast strains isolated from different traditional fermented foods and beverages. This article is protected by copyright. All rights reserved.

  5. Performance of statistical process control methods for regional surgical site infection surveillance: a 10-year multicentre pilot study.

    PubMed

    Baker, Arthur W; Haridy, Salah; Salem, Joseph; Ilieş, Iulian; Ergai, Awatef O; Samareh, Aven; Andrianas, Nicholas; Benneyan, James C; Sexton, Daniel J; Anderson, Deverick J

    2017-11-24

    Traditional strategies for surveillance of surgical site infections (SSI) have multiple limitations, including delayed and incomplete outbreak detection. Statistical process control (SPC) methods address these deficiencies by combining longitudinal analysis with graphical presentation of data. We performed a pilot study within a large network of community hospitals to evaluate performance of SPC methods for detecting SSI outbreaks. We applied conventional Shewhart and exponentially weighted moving average (EWMA) SPC charts to 10 previously investigated SSI outbreaks that occurred from 2003 to 2013. We compared the results of SPC surveillance to the results of traditional SSI surveillance methods. Then, we analysed the performance of modified SPC charts constructed with different outbreak detection rules, EWMA smoothing factors and baseline SSI rate calculations. Conventional Shewhart and EWMA SPC charts both detected 8 of the 10 SSI outbreaks analysed, in each case prior to the date of traditional detection. Among detected outbreaks, conventional Shewhart chart detection occurred a median of 12 months prior to outbreak onset and 22 months prior to traditional detection. Conventional EWMA chart detection occurred a median of 7 months prior to outbreak onset and 14 months prior to traditional detection. Modified Shewhart and EWMA charts additionally detected several outbreaks earlier than conventional SPC charts. Shewhart and SPC charts had low false-positive rates when used to analyse separate control hospital SSI data. Our findings illustrate the potential usefulness and feasibility of real-time SPC surveillance of SSI to rapidly identify outbreaks and improve patient safety. Further study is needed to optimise SPC chart selection and calculation, statistical outbreak detection rules and the process for reacting to signals of potential outbreaks. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  6. Compressive sensing method for recognizing cat-eye effect targets.

    PubMed

    Li, Li; Li, Hui; Dang, Ersheng; Liu, Bo

    2013-10-01

    This paper proposes a cat-eye effect target recognition method with compressive sensing (CS) and presents a recognition method (sample processing before reconstruction based on compressed sensing, or SPCS) for image processing. In this method, the linear projections of original image sequences are applied to remove dynamic background distractions and extract cat-eye effect targets. Furthermore, the corresponding imaging mechanism for acquiring active and passive image sequences is put forward. This method uses fewer images to recognize cat-eye effect targets, reduces data storage, and translates the traditional target identification, based on original image processing, into measurement vectors processing. The experimental results show that the SPCS method is feasible and superior to the shape-frequency dual criteria method.

  7. Reproducing the old masters: applying colour mixing and painting methodologies to inkjet printing

    NASA Astrophysics Data System (ADS)

    Olen, Melissa; Padfield, Joseph; Parraman, Carinna

    2014-01-01

    This research investigates multi-channel inkjet printing methods, which deviate from standard colour management workflows by reflecting on art historical processes, including the construction of colour in old master works, to reproduce specific colour pigment mixes in print. This is approached by incorporating artist colour mixing principles relevant to traditional art making processes through direct n-channel printing and the implementation of multiple pass printing. By demanding specific ink colourants to be employed in print, as well as the application of mixing colour though layering, we can mimic the effects of the traditional processes. These printing methods also generate colour through a variety of colour mixtures that may not have been employed or achieved by the printer driver. The objective of this research is to explore colour mixing and layering techniques in the printing of inkjet reproductions of original artworks that will maintain subtle colour transitions in dark shadow regions. While these colours are lost in traditional inkjet reproduction, by using direct n-channel editing capabilities to reproduce a painted original with high dynamic range we can improve colour variation in the shadow regions.

  8. Fatigue resistance of engine-driven rotary nickel-titanium instruments produced by new manufacturing methods.

    PubMed

    Gambarini, Gianluca; Grande, Nicola Maria; Plotino, Gianluca; Somma, Francesco; Garala, Manish; De Luca, Massimo; Testarelli, Luca

    2008-08-01

    The aim of the present study was to investigate whether cyclic fatigue resistance is increased for nickel-titanium instruments manufactured by using new processes. This was evaluated by comparing instruments produced by using the twisted method (TF; SybronEndo, Orange, CA) and those using the M-wire alloy (GTX; Dentsply Tulsa-Dental Specialties, Tulsa, OK) with instruments produced by a traditional NiTi grinding process (K3, SybronEndo). Tests were performed with a specific cyclic fatigue device that evaluated cycles to failure of rotary instruments inside curved artificial canals. Results indicated that size 06-25 TF instruments showed a significant increase (p < 0.05) in the mean number of cycles to failure when compared with size 06-25 K3 files. Size 06-20 K3 instruments showed no significant increase (p > 0.05) in the mean number of cycles to failure when compared with size 06-20 GT series X instruments. The new manufacturing process produced nickel-titanium rotary files (TF) significantly more resistant to fatigue than instruments produced with the traditional NiTi grinding process. Instruments produced with M-wire (GTX) were not found to be more resistant to fatigue than instruments produced with the traditional NiTi grinding process.

  9. [Thinking of study on secondary development of major traditional Chinese medicine varieties based on system theory].

    PubMed

    Cheng, Xu-Dong; Jia, Xiao-Bin; Feng, Liang; Jiang, Jun

    2013-12-01

    The secondary development of traditional Chinese medicines (TCMs) is an important content of TCM modernization process, as well as an important path for developing new TCM drugs. Under the guidance of the system theory, in response to the lack of the overall guideline and practical methods for the secondary development of TCMs at present, we introduced the overall thought of the secondary development of major TCM varieties, as well as the roles and contents of clinical research, pharmacology and pharmaceutics in the process of the secondary development of major TCM varieties, so as to provide systematic strategies and methods for the development of major TCM varieties.

  10. The Effect of Process Oriented Guided Inquiry Learning (POGIL) on 11th Graders' Conceptual Understanding of Electrochemistry

    ERIC Educational Resources Information Center

    Sen, Senol; Yilmaz, Ayhan; Geban, Ömer

    2016-01-01

    The purpose of this study was to investigate the effect of Process Oriented Guided Inquiry Learning (POGIL) method compared to traditional teaching method on 11th grade students' conceptual understanding of electrochemistry concepts. Participants were 115 students from a public school in Turkey. Nonequivalent control group design was used. Two…

  11. Functional porous composites by blending with solution-processable molecular pores.

    PubMed

    Jiang, S; Chen, L; Briggs, M E; Hasell, T; Cooper, A I

    2016-05-25

    We present a simple method for rendering non-porous materials porous by solution co-processing with organic cage molecules. This method can be used both for small functional molecules and for polymers, thus creating porous composites by molecular blending, rather than the more traditional approach of supporting functional molecules on pre-frabricated porous supports.

  12. Assessing Smart Phones for Generating Life-space Indicators.

    PubMed

    Wan, Neng; Qu, Wenyu; Whittington, Jackie; Witbrodt, Bradley C; Henderson, Mary Pearl; Goulding, Evan H; Schenk, A Katrin; Bonasera, Stephen J; Lin, Ge

    2013-04-01

    Life-space is a promising method for estimating older adults' functional status. However, traditional life-space measures are costly and time consuming because they often rely on active subject participation. This study assesses the feasibility of using the global positioning system (GPS) function of smart phones to generate life-space indicators. We first evaluated the location accuracy of smart phone collected GPS points versus those acquired by a commercial GPS unit. We then assessed the specificity of the smart phone processed life-space information against the traditional diary method. Our results suggested comparable location accuracy between the smart phone and the standard GPS unit in most outdoor situations. In addition, the smart phone method revealed more comprehensive life-space information than the diary method, which leads to higher and more consistent life-space scores. We conclude that the smart phone method is more reliable than traditional methods for measuring life-space. Further improvements will be required to develop a robust application of this method that is suitable for health-related practices.

  13. Community-based Inquiry Improves Critical Thinking in General Education Biology

    PubMed Central

    Faiola, Celia L.; Johnson, James E.; Kurtz, Martha J.

    2008-01-01

    National stakeholders are becoming increasingly concerned about the inability of college graduates to think critically. Research shows that, while both faculty and students deem critical thinking essential, only a small fraction of graduates can demonstrate the thinking skills necessary for academic and professional success. Many faculty are considering nontraditional teaching methods that incorporate undergraduate research because they more closely align with the process of doing investigative science. This study compared a research-focused teaching method called community-based inquiry (CBI) with traditional lecture/laboratory in general education biology to discover which method would elicit greater gains in critical thinking. Results showed significant critical-thinking gains in the CBI group but decreases in a traditional group and a mixed CBI/traditional group. Prior critical-thinking skill, instructor, and ethnicity also significantly influenced critical-thinking gains, with nearly all ethnicities in the CBI group outperforming peers in both the mixed and traditional groups. Females, who showed decreased critical thinking in traditional courses relative to males, outperformed their male counterparts in CBI courses. Through the results of this study, it is hoped that faculty who value both research and critical thinking will consider using the CBI method. PMID:18765755

  14. Feasibility study and sensory test of turmeric tamarind traditional drink with various processing

    NASA Astrophysics Data System (ADS)

    Rudyatmi, E.; Bintari, S. H.; Iswari, R. S.

    2018-03-01

    Turmeric tamarind traditional drink as anti-oxidant, good for health, and has a potency to developed. The objectives of this study are to determine the feasibility and the favorite level of consumer towards two turmerics tamarind traditional drink which processed differently. Feasibility depended on sensory test and microbe's contamination according to a quality standard of BPOM and complemented with an anti-bacterial test. The anti-bacterial test is determined by a diameter of inhibition zone towards E coli and B subtilist. Consumer’s favorites level is determined by organoleptic test to 40 testers. Sensory test results to form, odor, taste, and color are normal. TPC first traditional drink 6,9 x 102 col/gr and TKK ≤1,0x10 col/gr, TPC second traditional drink 2,0 x 101 col/gr and TKK ≤1,0x10 col/gr; all tests toward E coli, Salmonella SP, Staphylococcus aureus, Pseudomonas aeruginosa, shigella sp negative/gr; inhibiting capabilities towards B.subtilis and E coli of first traditional drink > second traditional drink. Inhibiting capabilities towards B.subtilis > E coli. All parameters comply with BPOM standard. Most of the tester love the first method turmeric tamarind traditional drink.

  15. The Effects of Process Oriented Guided Inquiry Learning on Secondary Student ACT Science Scores

    NASA Astrophysics Data System (ADS)

    Judd, William Lindsey

    The purpose of this study was to examine any significant difference on secondary school chemistry students' ACT Science Test scores between students taught by the Process Oriented Guided Inquiry Learning (POGIL) method versus students taught by traditional, teacher-centered pedagogy. This study also examined any difference between students taught by the POGIL method versus students taught by traditional, teacher-centered pedagogy in regard to the three different types of questions on the ACT Science Test: data representation, research summaries, and conflicting viewpoints. The sample consisted of sophomore-level students at two private, suburban Christian schools. A pretest-posttest design was used to compare the mean difference in scores from ACT issued sample test booklets before and after each group had received instruction via the POGIL method or more traditional methods. This study found that there was no significant difference in the mean difference of test scores between the two groups. This study also found that there was not a significant difference in the mean difference of scores in regard to the three different types of questions on the ACT Science Test. Further implications of this study are discussed.

  16. Mining knowledge in noisy audio data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Czyzewski, A.

    1996-12-31

    This paper demonstrates a KDD method applied to audio data analysis, particularly, it presents possibilities which result from replacing traditional methods of analysis and acoustic signal processing by KDD algorithms when restoring audio recordings affected by strong noise.

  17. Microscale patterning of thermoplastic polymer surfaces by selective solvent swelling.

    PubMed

    Rahmanian, Omid; Chen, Chien-Fu; DeVoe, Don L

    2012-09-04

    A new method for the fabrication of microscale features in thermoplastic substrates is presented. Unlike traditional thermoplastic microfabrication techniques, in which bulk polymer is displaced from the substrate by machining or embossing, a unique process termed orogenic microfabrication has been developed in which selected regions of a thermoplastic surface are raised from the substrate by an irreversible solvent swelling mechanism. The orogenic technique allows thermoplastic surfaces to be patterned using a variety of masking methods, resulting in three-dimensional features that would be difficult to achieve through traditional microfabrication methods. Using cyclic olefin copolymer as a model thermoplastic material, several variations of this process are described to realize growth heights ranging from several nanometers to tens of micrometers, with patterning techniques include direct photoresist masking, patterned UV/ozone surface passivation, elastomeric stamping, and noncontact spotting. Orogenic microfabrication is also demonstrated by direct inkjet printing as a facile photolithography-free masking method for rapid desktop thermoplastic microfabrication.

  18. Non-codified traditional medicine practices from Belgaum Region in Southern India: present scenario

    PubMed Central

    2014-01-01

    Background Traditional medicine in India can be classified into codified (Ayurveda, Unani, Siddha, Homeopathy) and non-codified (folk medicine) systems. Both the systems contributing equally to the primary healthcare in India. The present study is aimed to understand the current scenario of medicinal practices of non-codified system of traditional medicine in Belgaum region, India. Methods The study has been conducted as a basic survey of identified non-codified traditional practitioners by convenience sampling with semi structured, open ended interviews and discussions. The learning process, disease diagnosis, treatment, remuneration, sharing of knowledge and socio-demographic data was collected, analysed and discussed. Results One hundred and forty traditional practitioners were identified and interviewed for the present study. These practitioners are locally known as “Vaidya”. The study revealed that the non-codified healthcare tradition is practiced mainly by elderly persons in the age group of 61 years and above (40%). 73% of the practitioners learnt the tradition from their forefathers, and 19% of practitioners developed their own practices through experimentation, reading and learning. 20% of the practitioners follow distinctive “Nadi Pariksha” (pulse examination) for disease diagnosis, while others follow bodily symptoms and complaints. 29% of the traditional practitioners do not charge anything, while 59% practitioners receive money as remuneration. Plant and animal materials are used as sources of medicines, with a variety of preparation methods. The preference ranking test revealed higher education and migration from villages are the main reasons for decreasing interest amongst the younger generation, while deforestation emerged as the main cause of medicinal plants depletion. Conclusion Patrilineal transfer of the knowledge to younger generation was observed in Belgaum region. The observed resemblance in disease diagnosis, plant collection and processing between non-codified traditional system of medicine and Ayurveda require further methodical studies to establish the relationship between the two on a more objective basis. However, the practice appears to be at crossroads with threat of extinction, because of non-inheritance of the knowledge and non-availability of medicinal plants. Hence conservation strategies for both knowledge and resources at societal, scientific and legislative levels are urgently required to preserve the traditional wisdom. PMID:24934868

  19. Process Recording in Supervision of Students Learning to Practice with Children

    ERIC Educational Resources Information Center

    Mullin, Walter J.; Canning, James J.

    2007-01-01

    This article addresses the use of process recordings in supervising social work students learning to practice with children. Although process recordings are a traditional method of teaching and learning social work practice, they have received little attention in the literature of social work practice and social work education. Process recordings…

  20. Quality assessment of raw and processed Arctium lappa L. through multicomponent quantification, chromatographic fingerprint, and related chemometric analysis.

    PubMed

    Qin, Kunming; Wang, Bin; Li, Weidong; Cai, Hao; Chen, Danni; Liu, Xiao; Yin, Fangzhou; Cai, Baochang

    2015-05-01

    In traditional Chinese medicine, raw and processed herbs are used to treat different diseases. Suitable quality assessment methods are crucial for the discrimination between raw and processed herbs. The dried fruit of Arctium lappa L. and their processed products are widely used in traditional Chinese medicine, yet their therapeutic effects are different. In this study, a novel strategy using high-performance liquid chromatography and diode array detection coupled with multivariate statistical analysis to rapidly explore raw and processed Arctium lappa L. was proposed and validated. Four main components in a total of 30 batches of raw and processed Fructus Arctii samples were analyzed, and ten characteristic peaks were identified in the fingerprint common pattern. Furthermore, similarity evaluation, principal component analysis, and hierachical cluster analysis were applied to demonstrate the distinction. The results suggested that the relative amounts of the chemical components of raw and processed Fructus Arctii samples are different. This new method has been successfully applied to detect the raw and processed Fructus Arctii in marketed herbal medicinal products. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Cross-Cultural Equivalence and Psychometric Properties of the Traditional Chinese Version of the Inviting School Survey-Revised

    ERIC Educational Resources Information Center

    Smith, Kenneth H.

    2011-01-01

    The Inviting School Survey-Revised (ISS-R) was adapted and translated into Traditional Chinese (ISS-RC), using a five-step process, based on international test administration guidelines, involving judgmental, logical, and empirical methods. Both versions were administered to a convenience sample of Chinese-English fluent Hong Kong school community…

  2. Modelling energy and environmental impacts of traditional and improved shea butter production in West Africa for food security.

    PubMed

    Naughton, Colleen C; Zhang, Qiong; Mihelcic, James R

    2017-01-15

    This study improves the global application of methods and analyses, especially Life Cycle Assessment (LCA), that properly incorporates environmental impacts of firewood and a social sustainability indicator (human energy) as tools for sustainable human development. Specifically shea butter production processes, common throughout sub-Saharan Africa and crucial to food security, environmental sustainability, and women's empowerment, are analyzed. Many economic activities in the world rely on firewood for energy and labor that aren't included in traditional LCAs. Human energy (entirely from women) contributed 25-100% of shea butter production processes (2000-6100kJ/kg of shea butter) and mechanized production processes had reduced human energy without considerably greater total energy. Firewood accounted for 94-100% of total embodied energy (103 and 172MJ/kg of shea butter for improved and traditional shea butter production processes respectively) and global warming potential and 18-100% of human toxicity of the production processes. Implementation of improved cookstoves modeled in this study could reduce: (1) global warming potential by 78% (from 18 to 4.1kg CO 2 eq/kg and 11 to 2.4kg CO 2 eq/kg of shea butter for the traditional and improved processes respectively), (2) the embodied energy of using firewood by 52% (from 170 to 82MJ/kg and 103 to 49MJ/kg for the traditional and improved processes respectively), and (3) human toxicity by 83% for the non-mechanized traditional and improved processes (from 0.041 to 0.0071 1,4 DB eq/kg and 0.025 to 0.0042 1,4 DB eq/kg respectively). In addition, this is the first study to compare Economic Input-Output Life Cycle Assessment (EIO-LCA) and process-based LCA in a developing country and evaluate five traditional and improved shea butter production processes over different impact categories. Overall, this study developed a framework to evaluate and improve processes for achievement of the United Nation's Sustainable Development Goals for 2030 particularly to obtain food security. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. An Improved Spectral Analysis Method for Fatigue Damage Assessment of Details in Liquid Cargo Tanks

    NASA Astrophysics Data System (ADS)

    Zhao, Peng-yuan; Huang, Xiao-ping

    2018-03-01

    Errors will be caused in calculating the fatigue damages of details in liquid cargo tanks by using the traditional spectral analysis method which is based on linear system, for the nonlinear relationship between the dynamic stress and the ship acceleration. An improved spectral analysis method for the assessment of the fatigue damage in detail of a liquid cargo tank is proposed in this paper. Based on assumptions that the wave process can be simulated by summing the sinusoidal waves in different frequencies and the stress process can be simulated by summing the stress processes induced by these sinusoidal waves, the stress power spectral density (PSD) is calculated by expanding the stress processes induced by the sinusoidal waves into Fourier series and adding the amplitudes of each harmonic component with the same frequency. This analysis method can take the nonlinear relationship into consideration and the fatigue damage is then calculated based on the PSD of stress. Take an independent tank in an LNG carrier for example, the accuracy of the improved spectral analysis method is proved much better than that of the traditional spectral analysis method by comparing the calculated damage results with the results calculated by the time domain method. The proposed spectral analysis method is more accurate in calculating the fatigue damages in detail of ship liquid cargo tanks.

  4. Botanical drugs in Ayurveda and Traditional Chinese Medicine.

    PubMed

    Jaiswal, Yogini; Liang, Zhitao; Zhao, Zhongzhen

    2016-12-24

    China and India have a long history in the therapeutic application of botanical drugs in traditional medicine. Traditional Chinese Medicine (TCM) and Ayurveda are considered as two of the most ancient systems of medicine, with history of more than two millennia. Medicinal plants are the principal medicinal materials used in both these systems. This review discusses about the histories of Ayurveda and TCM, the common medicinal plants species, the drug processing strategies used, and the current statuses of these traditional systems of medicine (TSM). Through the views presented in this article, we aim to provide a new perspective to herbal drug researchers for expanding and improving the utilization of botanical drugs and their therapeutic applications. A bibliographic investigation of Chinese and Indian pharmacopoeias, monographs and official websites was performed. Furthermore, information was obtained from scientific databases on ethnobotany and ethno medicines. The review of Ayurveda and TCM ethno medicine indicates that both these systems have many medicinal materials in common. The studies carried out by the authors for comparison of plants from same genus from both these TSM's have been discussed to further bring focus to the utilization of "qualitatively" similar species which can be utilized and substituted for endangered or economically valued species. The overview of ancient literature and scientific findings for drugs in both these systems suggests that, the botanical drugs used in common and their processing methods can be explored further for extensive utilization in traditional medicine. This review describes the histories, common medicinal plant species, their processing methods and therapeutic applications in Ayurveda and TCM. The insights provided through this article may be used by herbal drug researchers and pharmacologists for further exploration of botanical drugs from these two traditional systems of medicine. Copyright © 2016. Published by Elsevier Ireland Ltd.

  5. [Online endpoint detection algorithm for blending process of Chinese materia medica].

    PubMed

    Lin, Zhao-Zhou; Yang, Chan; Xu, Bing; Shi, Xin-Yuan; Zhang, Zhi-Qiang; Fu, Jing; Qiao, Yan-Jiang

    2017-03-01

    Blending process, which is an essential part of the pharmaceutical preparation, has a direct influence on the homogeneity and stability of solid dosage forms. With the official release of Guidance for Industry PAT, online process analysis techniques have been more and more reported in the applications in blending process, but the research on endpoint detection algorithm is still in the initial stage. By progressively increasing the window size of moving block standard deviation (MBSD), a novel endpoint detection algorithm was proposed to extend the plain MBSD from off-line scenario to online scenario and used to determine the endpoint in the blending process of Chinese medicine dispensing granules. By online learning of window size tuning, the status changes of the materials in blending process were reflected in the calculation of standard deviation in a real-time manner. The proposed method was separately tested in the blending processes of dextrin and three other extracts of traditional Chinese medicine. All of the results have shown that as compared with traditional MBSD method, the window size changes according to the proposed MBSD method (progressively increasing the window size) could more clearly reflect the status changes of the materials in blending process, so it is suitable for online application. Copyright© by the Chinese Pharmaceutical Association.

  6. Exploiting interfacial water properties for desalination and purification applications.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xu, Hongwu; Varma, Sameer; Nyman, May Devan

    2008-09-01

    A molecular-scale interpretation of interfacial processes is often downplayed in the analysis of traditional water treatment methods. However, such an approach is critical for the development of enhanced performance in traditional desalination and water treatments. Water confined between surfaces, within channels, or in pores is ubiquitous in technology and nature. Its physical and chemical properties in such environments are unpredictably different from bulk water. As a result, advances in water desalination and purification methods may be accomplished through an improved analysis of water behavior in these challenging environments using state-of-the-art microscopy, spectroscopy, experimental, and computational methods.

  7. A novel data processing technique for image reconstruction of penumbral imaging

    NASA Astrophysics Data System (ADS)

    Xie, Hongwei; Li, Hongyun; Xu, Zeping; Song, Guzhou; Zhang, Faqiang; Zhou, Lin

    2011-06-01

    CT image reconstruction technique was applied to the data processing of the penumbral imaging. Compared with other traditional processing techniques for penumbral coded pinhole image such as Wiener, Lucy-Richardson and blind technique, this approach is brand new. In this method, the coded aperture processing method was used for the first time independent to the point spread function of the image diagnostic system. In this way, the technical obstacles was overcome in the traditional coded pinhole image processing caused by the uncertainty of point spread function of the image diagnostic system. Then based on the theoretical study, the simulation of penumbral imaging and image reconstruction was carried out to provide fairly good results. While in the visible light experiment, the point source of light was used to irradiate a 5mm×5mm object after diffuse scattering and volume scattering. The penumbral imaging was made with aperture size of ~20mm. Finally, the CT image reconstruction technique was used for image reconstruction to provide a fairly good reconstruction result.

  8. Hepatitis Diagnosis Using Facial Color Image

    NASA Astrophysics Data System (ADS)

    Liu, Mingjia; Guo, Zhenhua

    Facial color diagnosis is an important diagnostic method in traditional Chinese medicine (TCM). However, due to its qualitative, subjective and experi-ence-based nature, traditional facial color diagnosis has a very limited application in clinical medicine. To circumvent the subjective and qualitative problems of facial color diagnosis of Traditional Chinese Medicine, in this paper, we present a novel computer aided facial color diagnosis method (CAFCDM). The method has three parts: face Image Database, Image Preprocessing Module and Diagnosis Engine. Face Image Database is carried out on a group of 116 patients affected by 2 kinds of liver diseases and 29 healthy volunteers. The quantitative color feature is extracted from facial images by using popular digital image processing techni-ques. Then, KNN classifier is employed to model the relationship between the quantitative color feature and diseases. The results show that the method can properly identify three groups: healthy, severe hepatitis with jaundice and severe hepatitis without jaundice with accuracy higher than 73%.

  9. A Composite Model of Wound Segmentation Based on Traditional Methods and Deep Neural Networks

    PubMed Central

    Wang, Changjian; Liu, Xiaohui; Jin, Shiyao

    2018-01-01

    Wound segmentation plays an important supporting role in the wound observation and wound healing. Current methods of image segmentation include those based on traditional process of image and those based on deep neural networks. The traditional methods use the artificial image features to complete the task without large amounts of labeled data. Meanwhile, the methods based on deep neural networks can extract the image features effectively without the artificial design, but lots of training data are required. Combined with the advantages of them, this paper presents a composite model of wound segmentation. The model uses the skin with wound detection algorithm we designed in the paper to highlight image features. Then, the preprocessed images are segmented by deep neural networks. And semantic corrections are applied to the segmentation results at last. The model shows a good performance in our experiment. PMID:29955227

  10. Using internet-based approaches to collect qualitative data from vulnerable groups: reflections from the field.

    PubMed

    Neville, Stephen; Adams, Jeffery; Cook, Catherine

    2016-12-01

    Undertaking qualitative research with vulnerable populations is a complex and challenging process for researchers. Traditional and common modes of collecting qualitative data with these groups have been via face-to-face recorded interviews. This article reports on three internet-based data collection methods; email and synchronous online interviews, as well as online qualitative survey. The key characteristics of using email, sychronous online interviews and an online qualitative survey including the strengths and limitations of each are presented. Reflections and insights on the use of these internet-based data collection methods are provided to encourage researchers to embrace technology and move away from using traditional face-to-face interviews when researching with vulnerable populations. Using the internet to collect qualitative data offers additional ways to gather qualitative data over traditional data collection methods. The use of alternative interview methods may encourage participation of vulnerable participants.

  11. Methods for Conducting Cognitive Task Analysis for a Decision Making Task.

    DTIC Science & Technology

    1996-01-01

    Cognitive task analysis (CTA) improves traditional task analysis procedures by analyzing the thought processes of performers while they complete a...for using these methods to conduct a CTA for domains which involve critical decision making tasks in naturalistic settings. The cognitive task analysis methods

  12. Growing Organic Crystals By The Czochralski Method

    NASA Technical Reports Server (NTRS)

    Shields, Angela; Frazier, Donald O.; Penn, Benjamin G.; Aggarwal, M. D.; Wang, W. S.

    1994-01-01

    Apparatus grows high-quality single crystals of organic compounds by Czochralski method. In Czochralski process, growing crystal lifted from middle of molten material without touching walls. Because of low melting temperatures of organic crystals, glass vessels usable. Traditional method for inorganic semiconductors adapted to optically nonlinear organic materials.

  13. Personalizing Behavior Modification.

    ERIC Educational Resources Information Center

    White, Debra G.; And Others

    1987-01-01

    Process reinforcement is proposed as a reinforcement method that is more comfortable, personal, comprehensive, and interactive than traditional behavior modification. Process reinforcement strengthens desired behaviors by engaging learners in a one-on-one examination of how they achieved correct responses and by practicing comfortable eye contact…

  14. Enhancing healthcare process design with human factors engineering and reliability science, part 1: setting the context.

    PubMed

    Boston-Fleischhauer, Carol

    2008-01-01

    The design and implementation of efficient, effective, and safe processes are never-ending challenges in healthcare. Less than optimal performance levels and rising concerns about patient safety suggest that traditional process design methods are insufficient to meet design requirements. In this 2-part series, the author presents human factors engineering and reliability science as important knowledge to enhance existing operational and clinical process design methods in healthcare. An examination of these theories, application approaches, and examples are presented.

  15. Altering allergenicity of cow's milk by food processing for applications in infant formula.

    PubMed

    Golkar, Abdolkhalegh; Milani, Jafar M; Vasiljevic, Todor

    2018-04-16

    Cow's milk-based infant formulas have a long tradition in infant nutrition, although some infants are unable to use them due to presence of several known allergens. Various processing methods have been identified capable of reducing cow's milk protein allergenicity including thermal and non-thermal methods and their combinations. Heat treatment and enzymatic hydrolysis have been in production of hypoallergenic infant formulas. However, modulation of allergenic epitopes depends on the extent of heat treatment applied, which consequently may also reduce a nutritional value of these proteins. In addition, enzymatic hydrolysis may not target allergenic epitopes thus allergenicity may persist; however released peptides may have detrimental impact on taste and functional properties of final products. Modulation of allergenicity of milk proteins appears to require a concerted effort to minimize detrimental effects as clinical studies conducted on commercial hypoallergenic formulas demonstrated persistence of allergic symptoms. This article covers traditional and novel processing methods and their impact on reduction of cow's milk allergenicity in milk-based infant formulas.

  16. Novel DNPH-based method for determination of protein carbonylation in muscle and meat.

    PubMed

    Soglia, Francesca; Petracci, Massimiliano; Ertbjerg, Per

    2016-04-15

    Protein oxidation is considered an ongoing deteriorative process during storage of fresh and processed meat. Carbonyl compounds have traditionally been detected spectrophotometrically after derivatization with 2,4-dinitrophenylhydrazine (DNPH) to form protein-bound hydrazones with absorbance at 370 nm. Here we describe a novel DNPH-based method to quantify protein carbonylation in muscle and meat. The additional steps of the novel method aimed at increasing the protein solubility and inducing protein unfolding before labeling with DNPH. Compared to the traditional method, the new procedure reflected an increased protein carbonylation level measuring overall two to fourfold more carbonyls in muscles from different species as well as in soluble, salt-soluble and insoluble protein fractions. The study suggested that protein unfolding is a more important phenomenon than solubilization for increased DNPH labeling. The novel method resulted in three to fourfold larger carbonyl content determined in chicken, pork and beef (2.8, 3.6 and 3.1 nmol/mg of protein, respectively). Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. New parameters in adaptive testing of ferromagnetic materials utilizing magnetic Barkhausen noise

    NASA Astrophysics Data System (ADS)

    Pal'a, Jozef; Ušák, Elemír

    2016-03-01

    A new method of magnetic Barkhausen noise (MBN) measurement and optimization of the measured data processing with respect to non-destructive evaluation of ferromagnetic materials was tested. Using this method we tried to found, if it is possible to enhance sensitivity and stability of measurement results by replacing the traditional MBN parameter (root mean square) with some new parameter. In the tested method, a complex set of the MBN from minor hysteresis loops is measured. Afterward, the MBN data are collected into suitably designed matrices and optimal parameters of MBN with respect to maximum sensitivity to the evaluated variable are searched. The method was verified on plastically deformed steel samples. It was shown that the proposed measuring method and measured data processing bring an improvement of the sensitivity to the evaluated variable when comparing with measuring traditional MBN parameter. Moreover, we found a parameter of MBN, which is highly resistant to the changes of applied field amplitude and at the same time it is noticeably more sensitive to the evaluated variable.

  18. Source-based neurofeedback methods using EEG recordings: training altered brain activity in a functional brain source derived from blind source separation

    PubMed Central

    White, David J.; Congedo, Marco; Ciorciari, Joseph

    2014-01-01

    A developing literature explores the use of neurofeedback in the treatment of a range of clinical conditions, particularly ADHD and epilepsy, whilst neurofeedback also provides an experimental tool for studying the functional significance of endogenous brain activity. A critical component of any neurofeedback method is the underlying physiological signal which forms the basis for the feedback. While the past decade has seen the emergence of fMRI-based protocols training spatially confined BOLD activity, traditional neurofeedback has utilized a small number of electrode sites on the scalp. As scalp EEG at a given electrode site reflects a linear mixture of activity from multiple brain sources and artifacts, efforts to successfully acquire some level of control over the signal may be confounded by these extraneous sources. Further, in the event of successful training, these traditional neurofeedback methods are likely influencing multiple brain regions and processes. The present work describes the use of source-based signal processing methods in EEG neurofeedback. The feasibility and potential utility of such methods were explored in an experiment training increased theta oscillatory activity in a source derived from Blind Source Separation (BSS) of EEG data obtained during completion of a complex cognitive task (spatial navigation). Learned increases in theta activity were observed in two of the four participants to complete 20 sessions of neurofeedback targeting this individually defined functional brain source. Source-based EEG neurofeedback methods using BSS may offer important advantages over traditional neurofeedback, by targeting the desired physiological signal in a more functionally and spatially specific manner. Having provided preliminary evidence of the feasibility of these methods, future work may study a range of clinically and experimentally relevant brain processes where individual brain sources may be targeted by source-based EEG neurofeedback. PMID:25374520

  19. Determination of maize hardness by biospeckle and fuzzy granularity.

    PubMed

    Weber, Christian; Dai Pra, Ana L; Passoni, Lucía I; Rabal, Héctor J; Trivi, Marcelo; Poggio Aguerre, Guillermo J

    2014-09-01

    In recent years there has been renewed interest in the development of novel grain classification methods that could complement traditional empirical tests. A speckle pattern occurs when a laser beam illuminates an optically rough surface that flickers when the object is active and is called biospeckle. In this work, we use laser biospeckle to classify maize (Zea mays L.) kernel hardness. A series of grains of three types of maize were cut and illuminated by a laser. A series of images were then registered, stored, and processed. These were compared with results obtained by floating test. The laser speckle technique was effective in discriminating the grains based on the presence of floury or vitreous endosperm and could be considered a feasible alternative to traditional floating methods. The results indicate that this methodology can distinguish floury and vitreous grains. Moreover, the assay showed higher discrimination capability than traditional tests. It could be potentially useful for maize classification and to increase the efficiency of processing dry milling corn.

  20. Traditional methods v. new technologies - dilemmas for dietary assessment in large-scale nutrition surveys and studies: a report following an international panel discussion at the 9th International Conference on Diet and Activity Methods (ICDAM9), Brisbane, 3 September 2015.

    PubMed

    Amoutzopoulos, B; Steer, T; Roberts, C; Cade, J E; Boushey, C J; Collins, C E; Trolle, E; de Boer, E J; Ziauddeen, N; van Rossum, C; Buurma, E; Coyle, D; Page, P

    2018-01-01

    The aim of the present paper is to summarise current and future applications of dietary assessment technologies in nutrition surveys in developed countries. It includes the discussion of key points and highlights of subsequent developments from a panel discussion to address strengths and weaknesses of traditional dietary assessment methods (food records, FFQ, 24 h recalls, diet history with interviewer-assisted data collection) v. new technology-based dietary assessment methods (web-based and mobile device applications). The panel discussion 'Traditional methods v. new technologies: dilemmas for dietary assessment in population surveys', was held at the 9th International Conference on Diet and Activity Methods (ICDAM9), Brisbane, September 2015. Despite respondent and researcher burden, traditional methods have been most commonly used in nutrition surveys. However, dietary assessment technologies offer potential advantages including faster data processing and better data quality. This is a fast-moving field and there is evidence of increasing demand for the use of new technologies amongst the general public and researchers. There is a need for research and investment to support efforts being made to facilitate the inclusion of new technologies for rapid, accurate and representative data.

  1. Extrusion Process by Finite Volume Method Using OpenFoam Software

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Matos Martins, Marcelo; Tonini Button, Sergio; Divo Bressan, Jose

    The computational codes are very important tools to solve engineering problems. In the analysis of metal forming process, such as extrusion, this is not different because the computational codes allow analyzing the process with reduced cost. Traditionally, the Finite Element Method is used to solve solid mechanic problems, however, the Finite Volume Method (FVM) have been gaining force in this field of applications. This paper presents the velocity field and friction coefficient variation results, obtained by numerical simulation using the OpenFoam Software and the FVM to solve an aluminum direct cold extrusion process.

  2. Comparison of immunomagnetic separation/adenosine triphosphate rapid method to traditional culture-based method for E. coli and enterococci enumeration in wastewater

    USGS Publications Warehouse

    Bushon, R.N.; Likirdopulos, C.A.; Brady, A.M.G.

    2009-01-01

    Untreated wastewater samples from California, North Carolina, and Ohio were analyzed by the immunomagnetic separation/adenosine triphosphate (IMS/ATP) method and the traditional culture-based method for E. coli and enterococci concentrations. The IMS/ATP method concentrates target bacteria by immunomagnetic separation and then quantifies captured bacteria by measuring bioluminescence induced by release of ATP from the bacterial cells. Results from this method are available within 1 h from the start of sample processing. Significant linear correlations were found between the IMS/ATP results and results from traditional culture-based methods for E. coli and enterococci enumeration for one location in California, two locations in North Carolina, and one location in Ohio (r??values ranged from 0.87 to 0.97). No significant linear relation was found for a second location in California that treats a complex mixture of residential and industrial wastewater. With the exception of one location, IMS/ATP showed promise as a rapid method for the quantification of faecal-indicator organisms in wastewater.

  3. Challenges in Producing a Portfolio for Assessment: In Search of Underpinning Educational Theories

    ERIC Educational Resources Information Center

    Tisani, Nomathamsanqa

    2008-01-01

    The use of portfolios for assessment is gaining popularity in higher education. Despite acknowledged difficulties and flaws associated with this assessment method, portfolios have advantages over traditional methods. Handbooks on methods of constructing portfolios often emphasise the mechanics of the "process" of building portfolios.…

  4. The role of traditional health practitioners in Rural KwaZulu-Natal, South Africa: generic or mode specific?

    PubMed

    Zuma, Thembelihle; Wight, Daniel; Rochat, Tamsen; Moshabela, Mosa

    2016-08-22

    Traditional health practitioners (THPs) play a vital role in the health care of the majority of the South African population and elsewhere on the African continent. However, many studies have challenged the role of THPs in health care. Concerns raised in the literature include the rationale, safety and effectiveness of traditional health practices and methods, as well as what informs them. This paper explores the processes followed in becoming a traditional healer and how these processes are related to THP roles. A qualitative research design was adopted, using four repeat group discussions with nine THPs, as part of a larger qualitative study conducted within the HIV Treatment as Prevention trial in rural South Africa. THPs were sampled through the local THP association and snowballing techniques. Data collection approaches included photo-voice and community walks. The role identity theory and content analysis were used to explore the data following transcription and translation. In the context of rural Northern KwaZulu-Natal, three types of THPs were identified: 1) Isangoma (diviner); 2) Inyanga (one who focuses on traditional medical remedies) and 3) Umthandazi (faith healer). Findings revealed that THPs are called by ancestors to become healers and/or go through an intensive process of learning about traditional medicines including plant, animal or mineral substances to provide health care. Some THPs identified themselves primarily as one type of healer, while most occupied multiple healing categories, that is, they practiced across different healing types. Our study also demonstrates that THPs fulfil roles that are not specific to the type of healer they are, these include services that go beyond the uses of herbs for physical illnesses or divination. THPs serve roles which include, but are not limited to, being custodians of traditional African religion and customs, educators about culture, counsellors, mediators and spiritual protectors. THPs' mode specific roles are influenced by the processes by which they become healers. However, whichever type of healer they identified as, most THPs used similar, generic methods and practices to focus on the physical, spiritual, cultural, psychological, emotional and social elements of illness.

  5. Comparison of an automated Most Probable Number (MPN) technique to traditional plating methods for estimating populations of total aerobes, coliforms and E. coli associated with freshly processed broiler chickens

    USDA-ARS?s Scientific Manuscript database

    Traditional microbiological techniques for estimating populations of viable bacteria can be laborious and time consuming. The Most Probable Number (MPN) technique is especially tedious as multiple series of tubes must be inoculated at several different dilutions. Recently, an instrument (TEMPOTM) ...

  6. Study of activity based costing implementation for palm oil production using value-added and non-value-added activity consideration in PT XYZ palm oil mill

    NASA Astrophysics Data System (ADS)

    Sembiring, M. T.; Wahyuni, D.; Sinaga, T. S.; Silaban, A.

    2018-02-01

    Cost allocation at manufacturing industry particularly in Palm Oil Mill still widely practiced based on estimation. It leads to cost distortion. Besides, processing time determined by company is not in accordance with actual processing time in work station. Hence, the purpose of this study is to eliminates non-value-added activities therefore processing time could be shortened and production cost could be reduced. Activity Based Costing Method is used in this research to calculate production cost with Value Added and Non-Value-Added Activities consideration. The result of this study is processing time decreasing for 35.75% at Weighting Bridge Station, 29.77% at Sorting Station, 5.05% at Loading Ramp Station, and 0.79% at Sterilizer Station. Cost of Manufactured for Crude Palm Oil are IDR 5.236,81/kg calculated by Traditional Method, IDR 4.583,37/kg calculated by Activity Based Costing Method before implementation of Activity Improvement and IDR 4.581,71/kg after implementation of Activity Improvement Meanwhile Cost of Manufactured for Palm Kernel are IDR 2.159,50/kg calculated by Traditional Method, IDR 4.584,63/kg calculated by Activity Based Costing Method before implementation of Activity Improvement and IDR 4.582,97/kg after implementation of Activity Improvement.

  7. Design of an FT-NIR spectrometer for online quality analysis of traditional Chinese medicine manufacturing process

    NASA Astrophysics Data System (ADS)

    Zhu, Ren; Wu, Lan; Wang, Shiming; Ye, Linhua; Ding, Zhihua

    2008-03-01

    As a fast, non-destructive analysis method, Fourier transform (FT) near-infrared (NIR) spectroscopy is very suitable and effective for online quality analysis of traditional Chinese medicine (TCM) manufacturing process. In this thesis, the theoretics of FT-NIRS was analyzed and an FT-NIR spectrometer with 4 cm -1 resolution in the 12500-5000 cm -1 frequency range was designed. The spectrometer was based on a Michelson interferometer with Bromine tungsten lamp as the NIR light source and InGaAs detector to collect the interference signal. Each element was designed and chosen to provide maximum sensitivity in the NIR spectral region. A fiber-optic flow cell system was used to realize online analysis of traditional Chinese medicine. The performance of the spectrometer was evaluated and the feasibility of using FT-NIR spectrometer to get absorption spectra of traditional Chinese medicine was demonstrated.

  8. Automation in the Teaching of Descriptive Geometry and CAD. High-Level CAD Templates Using Script Languages

    NASA Astrophysics Data System (ADS)

    Moreno, R.; Bazán, A. M.

    2017-10-01

    The main purpose of this work is to study improvements to the learning method of technical drawing and descriptive geometry through exercises with traditional techniques that are usually solved manually by applying automated processes assisted by high-level CAD templates (HLCts). Given that an exercise with traditional procedures can be solved, detailed step by step in technical drawing and descriptive geometry manuals, CAD applications allow us to do the same and generalize it later, incorporating references. Traditional teachings have become obsolete and current curricula have been relegated. However, they can be applied in certain automation processes. The use of geometric references (using variables in script languages) and their incorporation into HLCts allows the automation of drawing processes. Instead of repeatedly creating similar exercises or modifying data in the same exercises, users should be able to use HLCts to generate future modifications of these exercises. This paper introduces the automation process when generating exercises based on CAD script files, aided by parametric geometry calculation tools. The proposed method allows us to design new exercises without user intervention. The integration of CAD, mathematics, and descriptive geometry facilitates their joint learning. Automation in the generation of exercises not only saves time but also increases the quality of the statements and reduces the possibility of human error.

  9. NONSTATIONARY SPATIAL MODELING OF ENVIRONMENTAL DATA USING A PROCESS CONVOLUTION APPROACH

    EPA Science Inventory

    Traditional approaches to modeling spatial processes involve the specification of the covariance structure of the field. Although such methods are straightforward to understand and effective in some situations, there are often problems in incorporating non-stationarity and in ma...

  10. Evaluation of a Freezer Mill for Bone Pulverization prior to DNA Extraction: An Improved Workflow for STR Analysis.

    PubMed

    Morales Colón, Emely; Hernández, Mireya; Candelario, Mariel; Meléndez, María; Dawson Cruz, Tracey

    2018-03-01

    Traditional methods for bone pulverization typically generate heat, risking stability of DNA sample. SPEX™ has developed cryogenic grinders which introduce liquid nitrogen to cool the sample and aid in the grinding process. In this study, the Freezer Mill 6970 EFM was used with two DNA extraction methods and routine downstream STR analysis procedures. DNA from as little as 0.1 g of bone powder was used to develop full STR profiles after freezer mill pulverization, and the method was reproducible. Further, no contamination was detected upon cleaning/reuse of the sample vials. There were no significant differences in DNA yield, STR alleles detected, or peak heights using the freezer mill as compared to traditional grinding, and successful DNA profiles were achieved from as low as 0.1 g of bone powder with this method. Overall, this work indicates that this cryogenic mill method may be used as a viable alternative to traditional tissue grinders. © 2017 American Academy of Forensic Sciences.

  11. An Intelligent Optical Dissolved Oxygen Measurement Method Based on a Fluorescent Quenching Mechanism.

    PubMed

    Li, Fengmei; Wei, Yaoguang; Chen, Yingyi; Li, Daoliang; Zhang, Xu

    2015-12-09

    Dissolved oxygen (DO) is a key factor that influences the healthy growth of fishes in aquaculture. The DO content changes with the aquatic environment and should therefore be monitored online. However, traditional measurement methods, such as iodometry and other chemical analysis methods, are not suitable for online monitoring. The Clark method is not stable enough for extended periods of monitoring. To solve these problems, this paper proposes an intelligent DO measurement method based on the fluorescence quenching mechanism. The measurement system is composed of fluorescent quenching detection, signal conditioning, intelligent processing, and power supply modules. The optical probe adopts the fluorescent quenching mechanism to detect the DO content and solves the problem, whereas traditional chemical methods are easily influenced by the environment. The optical probe contains a thermistor and dual excitation sources to isolate visible parasitic light and execute a compensation strategy. The intelligent processing module adopts the IEEE 1451.2 standard and realizes intelligent compensation. Experimental results show that the optical measurement method is stable, accurate, and suitable for online DO monitoring in aquaculture applications.

  12. An Intelligent Optical Dissolved Oxygen Measurement Method Based on a Fluorescent Quenching Mechanism

    PubMed Central

    Li, Fengmei; Wei, Yaoguang; Chen, Yingyi; Li, Daoliang; Zhang, Xu

    2015-01-01

    Dissolved oxygen (DO) is a key factor that influences the healthy growth of fishes in aquaculture. The DO content changes with the aquatic environment and should therefore be monitored online. However, traditional measurement methods, such as iodometry and other chemical analysis methods, are not suitable for online monitoring. The Clark method is not stable enough for extended periods of monitoring. To solve these problems, this paper proposes an intelligent DO measurement method based on the fluorescence quenching mechanism. The measurement system is composed of fluorescent quenching detection, signal conditioning, intelligent processing, and power supply modules. The optical probe adopts the fluorescent quenching mechanism to detect the DO content and solves the problem, whereas traditional chemical methods are easily influenced by the environment. The optical probe contains a thermistor and dual excitation sources to isolate visible parasitic light and execute a compensation strategy. The intelligent processing module adopts the IEEE 1451.2 standard and realizes intelligent compensation. Experimental results show that the optical measurement method is stable, accurate, and suitable for online DO monitoring in aquaculture applications. PMID:26690176

  13. Cognitive Process Modeling of Spatial Ability: The Assembling Objects Task

    ERIC Educational Resources Information Center

    Ivie, Jennifer L.; Embretson, Susan E.

    2010-01-01

    Spatial ability tasks appear on many intelligence and aptitude tests. Although the construct validity of spatial ability tests has often been studied through traditional correlational methods, such as factor analysis, less is known about the cognitive processes involved in solving test items. This study examines the cognitive processes involved in…

  14. Sustainability Characterization for Additive Manufacturing.

    PubMed

    Mani, Mahesh; Lyons, Kevin W; Gupta, S K

    2014-01-01

    Additive manufacturing (AM) has the potential to create geometrically complex parts that require a high degree of customization, using less material and producing less waste. Recent studies have shown that AM can be an economically viable option for use by the industry, yet there are some inherent challenges associated with AM for wider acceptance. The lack of standards in AM impedes its use for parts production since industries primarily depend on established standards in processes and material selection to ensure the consistency and quality. Inability to compare AM performance against traditional manufacturing methods can be a barrier for implementing AM processes. AM process sustainability has become a driver due to growing environmental concerns for manufacturing. This has reinforced the importance to understand and characterize AM processes for sustainability. Process characterization for sustainability will help close the gaps for comparing AM performance to traditional manufacturing methods. Based on a literature review, this paper first examines the potential environmental impacts of AM. A methodology for sustainability characterization of AM is then proposed to serve as a resource for the community to benchmark AM processes for sustainability. Next, research perspectives are discussed along with relevant standardization efforts.

  15. Android malware detection based on evolutionary super-network

    NASA Astrophysics Data System (ADS)

    Yan, Haisheng; Peng, Lingling

    2018-04-01

    In the paper, an android malware detection method based on evolutionary super-network is proposed in order to improve the precision of android malware detection. Chi square statistics method is used for selecting characteristics on the basis of analyzing android authority. Boolean weighting is utilized for calculating characteristic weight. Processed characteristic vector is regarded as the system training set and test set; hyper edge alternative strategy is used for training super-network classification model, thereby classifying test set characteristic vectors, and it is compared with traditional classification algorithm. The results show that the detection method proposed in the paper is close to or better than traditional classification algorithm. The proposed method belongs to an effective Android malware detection means.

  16. Affordable Design: A Methodolgy to Implement Process-Based Manufacturing Cost into the Traditional Performance-Focused Multidisciplinary Design Optimization

    NASA Technical Reports Server (NTRS)

    Bao, Han P.; Samareh, J. A.

    2000-01-01

    The primary objective of this paper is to demonstrate the use of process-based manufacturing and assembly cost models in a traditional performance-focused multidisciplinary design and optimization process. The use of automated cost-performance analysis is an enabling technology that could bring realistic processbased manufacturing and assembly cost into multidisciplinary design and optimization. In this paper, we present a new methodology for incorporating process costing into a standard multidisciplinary design optimization process. Material, manufacturing processes, and assembly processes costs then could be used as the objective function for the optimization method. A case study involving forty-six different configurations of a simple wing is presented, indicating that a design based on performance criteria alone may not necessarily be the most affordable as far as manufacturing and assembly cost is concerned.

  17. [Investigation on Spray Drying Technology of Auricularia auricular Extract].

    PubMed

    Zhou, Rong; Chen, Hui; Xie, Yuan; Chen, Peng; Wang, Luo-lin

    2015-07-01

    To investigate the feasibility of spray drying technology of Auricularia auricular extract and its optimum process. On the basis of single factor test, with the yield of dry extract and the content of polysaccharide as indexes, orthogonal test method was used to optimize the spray drying technology on the inlet air temperature, injection speed and crude drug content. Using ultraviolet spectrophotometry, thin layer chromatography(TLC) and pharmacodynamics as indicators, extracts prepared by traditional alcohol precipitation drying process and spray drying process were compared. Compared with the traditional preparation method, the extract prepared by spray drying had little differences from the polysaccharide content, TLC and the function of reducing TG and TC, and its optimum technology condition were as follows: The inlet air temperature was 180 °C, injection speed was 10 ml/min and crude drugs content was 0. 4 g/mL. Auricularia auricular extract by spray drying technology is stable and feasible with high economic benefit.

  18. Preliminary study on the inactivation of anisakid larvae in baccalà prepared according to traditional methods.

    PubMed

    Smaldone, Giorgio; Marrone, Raffaele; Palma, Giuseppe; Sarnelli, Paolo; Anastasio, Aniello

    2017-10-20

    The European Food Safety Authority stated that many traditional marinating and cold smoking methods are not sufficient to kill A. simplex and asked to evaluate alternative treatments for killing viable parasites in fishery . Baccalà is a well-liked traditional product. The aim of study was to evaluate the effectiveness of the salting process on the inactivation of nematodes of the genus Anisakis in naturally infected Baccalà fillets. N. 19 fillets, subjected to a dual salting process (brine and dry salting) were analyzed. Visual inspection and chloropeptic digestion were performed. Larvae viability was evaluated, and parameters such as NaCl (%), moisture (%), WPS and a w were determined. In n. 17 samples parasites were found 123 parasites with a mean intensity of 7.23±4.78 and an mean abundance of 6.47±5.05. Visual examination has revealed 109 parasites. 61.8% of larvae were found in the ventral portions. The results show that salting process with a salt concentration of 18.6%, a w values of 0.7514 and 24.15% WPS in all parts of baccalà fillets, devitalise Anisakidae larvae in a 15-day period.

  19. Preliminary study on the inactivation of anisakid larvae in baccalà prepared according to traditional methods

    PubMed Central

    Smaldone, Giorgio; Marrone, Raffaele; Palma, Giuseppe; Sarnelli, Paolo; Anastasio, Aniello

    2017-01-01

    The European Food Safety Authority stated that many traditional marinating and cold smoking methods are not sufficient to kill A. simplex and asked to evaluate alternative treatments for killing viable parasites in fishery. Baccalà is a well-liked traditional product. The aim of study was to evaluate the effectiveness of the salting process on the inactivation of nematodes of the genus Anisakis in naturally infected Baccalà fillets. N. 19 fillets, subjected to a dual salting process (brine and dry salting) were analyzed. Visual inspection and chloropeptic digestion were performed. Larvae viability was evaluated, and parameters such as NaCl (%), moisture (%), WPS and aw were determined. In n. 17 samples parasites were found 123 parasites with a mean intensity of 7.23±4.78 and an mean abundance of 6.47±5.05. Visual examination has revealed 109 parasites. 61.8% of larvae were found in the ventral portions. The results show that salting process with a salt concentration of 18.6%, aw values of 0.7514 and 24.15% WPS in all parts of baccalà fillets, devitalise Anisakidae larvae in a 15-day period. PMID:29564240

  20. A Method of Classifying Tongue Colors for Traditional Chinese Medicine Diagnosis Based on the CIELAB Color Space

    NASA Astrophysics Data System (ADS)

    Li, Bocong; Huang, Qingmei; Lu, Yan; Chen, Songhe; Liang, Rong; Wang, Zhaoping

    Objective tongue color analysis is an important research point for tongue diagnosis in Traditional Chinese Medicine. In this paper a research based on the clinical process of diagnosing tongue color is reported. The color data in RGB color space were first transformed into the data in CIELAB color space, and the color gamut of the displayed tongue was obtained. Then a numerical method of tongue color classification based on the Traditional Chinese Medicine (for example: light white tongue, light red tongue, red tongue) was developed. The conclusion is that this research can give the description and classification of the tongue color close to those given by human vision and may be carried out in clinical diagnosis.

  1. [Applications of near-infrared spectroscopy to analysis of traditional Chinese herbal medicine].

    PubMed

    Li, Yan-Zhou; Min, Shun-Geng; Liu, Xia

    2008-07-01

    Analysis of traditional Chinese herbal medicine is of great importance to its quality control Conventional analysis methods can not meet the requirement of rapid and on-line analysis because of complex process more experiences or needed. In recent years, near-infrared spectroscopy technique has been used for rapid determination of active components, on-line quality control, identification of counterfeit and discrimination of geographical origins of herbal medicines and so on, due to its advantages of simple pretreatment, high efficiency, convenience to use solid diffuse reflection spectroscopy and fiber. In the present paper, the principles and methods of near-infrared spectroscopy technique are introduced concisely. Especially, the applications of this technique in quantitative analysis and qualitative analysis of traditional Chinese herbal medicine are reviewed.

  2. The performance evaluation model of mining project founded on the weight optimization entropy value method

    NASA Astrophysics Data System (ADS)

    Mao, Chao; Chen, Shou

    2017-01-01

    According to the traditional entropy value method still have low evaluation accuracy when evaluating the performance of mining projects, a performance evaluation model of mineral project founded on improved entropy is proposed. First establish a new weight assignment model founded on compatible matrix analysis of analytic hierarchy process (AHP) and entropy value method, when the compatibility matrix analysis to achieve consistency requirements, if it has differences between subjective weights and objective weights, moderately adjust both proportions, then on this basis, the fuzzy evaluation matrix for performance evaluation. The simulation experiments show that, compared with traditional entropy and compatible matrix analysis method, the proposed performance evaluation model of mining project based on improved entropy value method has higher accuracy assessment.

  3. Research on registration algorithm for check seal verification

    NASA Astrophysics Data System (ADS)

    Wang, Shuang; Liu, Tiegen

    2008-03-01

    Nowadays seals play an important role in China. With the development of social economy, the traditional method of manual check seal identification can't meet the need s of banking transactions badly. This paper focus on pre-processing and registration algorithm for check seal verification using theory of image processing and pattern recognition. First of all, analyze the complex characteristics of check seals. To eliminate the difference of producing conditions and the disturbance caused by background and writing in check image, many methods are used in the pre-processing of check seal verification, such as color components transformation, linearity transform to gray-scale image, medium value filter, Otsu, close calculations and labeling algorithm of mathematical morphology. After the processes above, the good binary seal image can be obtained. On the basis of traditional registration algorithm, a double-level registration method including rough and precise registration method is proposed. The deflection angle of precise registration method can be precise to 0.1°. This paper introduces the concepts of difference inside and difference outside and use the percent of difference inside and difference outside to judge whether the seal is real or fake. The experimental results of a mass of check seals are satisfied. It shows that the methods and algorithmic presented have good robustness to noise sealing conditions and satisfactory tolerance of difference within class.

  4. Remaining Useful Life Prediction for Lithium-Ion Batteries Based on Gaussian Processes Mixture

    PubMed Central

    Li, Lingling; Wang, Pengchong; Chao, Kuei-Hsiang; Zhou, Yatong; Xie, Yang

    2016-01-01

    The remaining useful life (RUL) prediction of Lithium-ion batteries is closely related to the capacity degeneration trajectories. Due to the self-charging and the capacity regeneration, the trajectories have the property of multimodality. Traditional prediction models such as the support vector machines (SVM) or the Gaussian Process regression (GPR) cannot accurately characterize this multimodality. This paper proposes a novel RUL prediction method based on the Gaussian Process Mixture (GPM). It can process multimodality by fitting different segments of trajectories with different GPR models separately, such that the tiny differences among these segments can be revealed. The method is demonstrated to be effective for prediction by the excellent predictive result of the experiments on the two commercial and chargeable Type 1850 Lithium-ion batteries, provided by NASA. The performance comparison among the models illustrates that the GPM is more accurate than the SVM and the GPR. In addition, GPM can yield the predictive confidence interval, which makes the prediction more reliable than that of traditional models. PMID:27632176

  5. Examining the extraction of artemisinin from artemisia annua using ultrasound

    NASA Astrophysics Data System (ADS)

    Briars, Rhianna; Paniwnyk, Larysa

    2012-05-01

    Artemisinin suppresses the life-cycle of the plasmodium parasite which causes malaria. It is found naturally occurring within the trichome glands of the Artemisia annua plant. Traditional methods for extracting artemisinin are time-consuming and have high environmental impact due to the temperatures and organic solvents which must be employed. Ultrasound decreases these through acoustic streaming and micro-jets. But to fully utilise this technology parameters, such as frequency, temperature and the properties of leaf and solvent, must be explored. As with the extraction process there is also no set analysis method for identification of artemisinin. Therefore several methods of analysing these extracts are employed. Initial results indicate that sonication is able to enhance levels of artemisinin extracted when compared to the conventional/traditional extraction process. In addition Thin Layer Chromatography (TLC) and High Performance Liquid Chromatography (HPLC) have been shown to have a high level of reproducible calibration.

  6. [An Improved Spectral Quaternion Interpolation Method of Diffusion Tensor Imaging].

    PubMed

    Xu, Yonghong; Gao, Shangce; Hao, Xiaofei

    2016-04-01

    Diffusion tensor imaging(DTI)is a rapid development technology in recent years of magnetic resonance imaging.The diffusion tensor interpolation is a very important procedure in DTI image processing.The traditional spectral quaternion interpolation method revises the direction of the interpolation tensor and can preserve tensors anisotropy,but the method does not revise the size of tensors.The present study puts forward an improved spectral quaternion interpolation method on the basis of traditional spectral quaternion interpolation.Firstly,we decomposed diffusion tensors with the direction of tensors being represented by quaternion.Then we revised the size and direction of the tensor respectively according to different situations.Finally,we acquired the tensor of interpolation point by calculating the weighted average.We compared the improved method with the spectral quaternion method and the Log-Euclidean method by the simulation data and the real data.The results showed that the improved method could not only keep the monotonicity of the fractional anisotropy(FA)and the determinant of tensors,but also preserve the tensor anisotropy at the same time.In conclusion,the improved method provides a kind of important interpolation method for diffusion tensor image processing.

  7. [Risk control of traditional Chinese medicines containing aristolochis acids (AAs) based on influencing factors of content of AAs].

    PubMed

    Tian, Jing-Zhuo; Liang, Ai-Hua; Liu, Jing; Zhang, Bo-Li

    2017-12-01

    Aristolochic acids (AAs) widely exist in such plants as Aristolochia and Asarum. The renal toxicity of AAs as well as its carcinogenicity to urinary system have been widely known. In 2003 and 2004, China prohibited the use of Aristolochiae Radix, Aristolochiae Manshuriensis Caulis and Aristolochiae Fangchi Radix, and required administering other AAs-containing medicines in accordance with the regulations for prescription drugs. In this paper, we retrieved literatures on the content determination of AAs in recent 10 years in China. It suggested that the AAs content is lower in Asarum herb, especially in its roots and rhizomes, and most of which do not show detectable amount of AA-I. Some of traditional Chinese medicines show fairly small amount of detectable AA-I. The AAs content in Aristolochia herb (including Fructus Aristolochiae, kaempfer dutchmanspipe root) is relatively high; however, there are fewer literatures for studying the content determination of AAs in Chinese patent medicines. There were many factors affecting AAs content, including the parts used, origins, processing methods, extraction process. It suggested that we should pay attention to the toxicity of Chinese medicines containing AAs and use these decoction pieces and traditional Chinese medicines cautiously. In addition, basic studies for the origins, processing methods and extraction process of Chinese patent medicines containing AAs, as well as supervision and detection of AAs content in traditional Chinese medicinal materials, decoction pieces and Chinese patent medicines shall be strengthened for reducing medication risk and guaranteeing clinical medication safety. Copyright© by the Chinese Pharmaceutical Association.

  8. Talk that talk: storytelling and analysis rooted in African American oral tradition.

    PubMed

    Banks-Wallace, JoAnne

    2002-03-01

    Stories are the foundation of qualitative research. However, the development of qualitative methods rooted in oral traditions remains largely unexplored by researchers. The contextual and historical influences on storytelling and storytaking are critical features of the African American oral tradition that are often ignored or minimized in qualitative research. Despite the complex and often contentious history of African Americans, their oral traditions have not been explored to reveal the depth of their lived experiences and the way those experiences inform their health concerns. The purpose of this article is twofold. First, dialogues about storytelling and storytaking are revisited and critiqued. Second, a comprehensive analytic process for gathering and interpreting stories rooted in African American oral tradition is outlined.

  9. Indian medical students' perspectives on problem-based learning experiences in the undergraduate curriculum: One size does not fit all.

    PubMed

    Nanda, Bijli; Manjunatha, Shankarappa

    2013-01-01

    Problem-based learning (PBL) is a well-established method for facilitating the learning of basic science concepts in the context of clinical cases. Relevant evidence is lacking regarding PBL's effectiveness and acceptability as perceived by students accustomed to classical traditional teaching in India. Hence, this study gathered students' opinions on PBL versus Traditional teaching methods to generate a foundation for institutional policymaking and ultimately, changes in the policy of regulatory bodies. A total of 773 first year medical students admitted from 2007-2010 in Kasturba Medical College Manipal, Manipal University, India were asked to respond to a 15-item questionnaire evaluating their preferences for PBL or traditional methods such as lectures after undergoing a systematically conducted PBL session in physiology. Their responses were analyzed with an unpaired t-test. Their comments were also collected. PBL scored significantly higher for most items in the questionnaire for "learning efficiency" and "student-teacher relationship". The students' comments highlighted the importance of a trained tutor/facilitator to enhance the learning process. Our students are willing to adapt to the PBL method, although they recognize certain benefits of traditional pedagogy. For learning efficiency and the student-teacher relationship, the students feel that neither method holds an advantage. We recommend that the future medical curriculum in India be a hybrid form of PBL and traditional methods with specific training on the unfamiliar PBL approach for both faculty and students.

  10. Syntactic Processing in the Human Brain: What We Know, What We Don't Know, and a Suggestion for How to Proceed

    ERIC Educational Resources Information Center

    Fedorenko, Evelina; Nieto-Castanon, Alfonso; Kanwisher, Nancy

    2012-01-01

    For every claim in the neuroimaging literature about a particular brain region supporting syntactic processing, there exist other claims implicating the target region in different linguistic processes, and, in many cases, in non-linguistic cognitive processes (e.g., Blumstein, 2009). We argue that traditional group analysis methods in neuroimaging…

  11. Development and Validation of an Instrument to Assess the Implementation of Family-Centred Care in Traditional Open Bay Neonatal Intensive Care Units

    ERIC Educational Resources Information Center

    Al-Motlaq, Mohammad A.; Abuidhail, Jamila; Salameh, Taghreed; Awwad, Wesam

    2017-01-01

    Objective: To develop an instrument to study family-centred care (FCC) in traditional open bay Neonatal Intensive Care Units (NICUs). Methods: The development process involved constructing instrument's items, establishing content validity by an expert panel and testing the instrument for validity and reliability with a convenience sample of 25…

  12. Integrating traditional nursing service orientation content with electronic medical record orientation.

    PubMed

    Harton, Brenda B; Borrelli, Larry; Knupp, Ann; Rogers, Necolen; West, Vickie R

    2009-01-01

    Traditional nursing service orientation classes at an acute care hospital were integrated with orientation to the electronic medical record to blend the two components in a user-friendly format so that the learner is introduced to the culture, processes, and documentation methods of the organization, with an opportunity to document online in a practice domain while lecture and discussion information is fresh.

  13. Research on signal processing method for total organic carbon of water quality online monitor

    NASA Astrophysics Data System (ADS)

    Ma, R.; Xie, Z. X.; Chu, D. Z.; Zhang, S. W.; Cao, X.; Wu, N.

    2017-08-01

    At present, there is no rapid, stable and effective approach of total organic carbon (TOC) measurement in the Marine environmental online monitoring field. Therefore, this paper proposes an online TOC monitor of chemiluminescence signal processing method. The weak optical signal detected by photomultiplier tube can be enhanced and converted by a series of signal processing module: phase-locked amplifier module, fourth-order band pass filter module and AD conversion module. After a long time of comparison test & measurement, compared with the traditional method, on the premise of sufficient accuracy, this chemiluminescence signal processing method can offer greatly improved measuring speed and high practicability for online monitoring.

  14. Dendritic tree extraction from noisy maximum intensity projection images in C. elegans.

    PubMed

    Greenblum, Ayala; Sznitman, Raphael; Fua, Pascal; Arratia, Paulo E; Oren, Meital; Podbilewicz, Benjamin; Sznitman, Josué

    2014-06-12

    Maximum Intensity Projections (MIP) of neuronal dendritic trees obtained from confocal microscopy are frequently used to study the relationship between tree morphology and mechanosensory function in the model organism C. elegans. Extracting dendritic trees from noisy images remains however a strenuous process that has traditionally relied on manual approaches. Here, we focus on automated and reliable 2D segmentations of dendritic trees following a statistical learning framework. Our dendritic tree extraction (DTE) method uses small amounts of labelled training data on MIPs to learn noise models of texture-based features from the responses of tree structures and image background. Our strategy lies in evaluating statistical models of noise that account for both the variability generated from the imaging process and from the aggregation of information in the MIP images. These noisy models are then used within a probabilistic, or Bayesian framework to provide a coarse 2D dendritic tree segmentation. Finally, some post-processing is applied to refine the segmentations and provide skeletonized trees using a morphological thinning process. Following a Leave-One-Out Cross Validation (LOOCV) method for an MIP databse with available "ground truth" images, we demonstrate that our approach provides significant improvements in tree-structure segmentations over traditional intensity-based methods. Improvements for MIPs under various imaging conditions are both qualitative and quantitative, as measured from Receiver Operator Characteristic (ROC) curves and the yield and error rates in the final segmentations. In a final step, we demonstrate our DTE approach on previously unseen MIP samples including the extraction of skeletonized structures, and compare our method to a state-of-the art dendritic tree tracing software. Overall, our DTE method allows for robust dendritic tree segmentations in noisy MIPs, outperforming traditional intensity-based methods. Such approach provides a useable segmentation framework, ultimately delivering a speed-up for dendritic tree identification on the user end and a reliable first step towards further morphological characterizations of tree arborization.

  15. MEASUREMENT OF VOCS DESORBED FROM BUILDING MATERIALS--A HIGH TEMPERATURE DYNAMIC CHAMBER METHOD

    EPA Science Inventory

    Mass balance is a commonly used approach for characterizing the source and sink behavior of building materials. Because the traditional sink test methods evaluate the adsorption and desorption of volatile organic compounds (VOC) at ambient temperatures, the desorption process is...

  16. ITPI: Initial Transcription Process-Based Identification Method of Bioactive Components in Traditional Chinese Medicine Formula

    PubMed Central

    Zhang, Baixia; Li, Yanwen; Zhang, Yanling; Li, Zhiyong; Bi, Tian; He, Yusu; Song, Kuokui; Wang, Yun

    2016-01-01

    Identification of bioactive components is an important area of research in traditional Chinese medicine (TCM) formula. The reported identification methods only consider the interaction between the components and the target proteins, which is not sufficient to explain the influence of TCM on the gene expression. Here, we propose the Initial Transcription Process-based Identification (ITPI) method for the discovery of bioactive components that influence transcription factors (TFs). In this method, genome-wide chip detection technology was used to identify differentially expressed genes (DEGs). The TFs of DEGs were derived from GeneCards. The components influencing the TFs were derived from STITCH. The bioactive components in the formula were identified by evaluating the molecular similarity between the components in formula and the components that influence the TF of DEGs. Using the formula of Tian-Zhu-San (TZS) as an example, the reliability and limitation of ITPI were examined and 16 bioactive components that influence TFs were identified. PMID:27034696

  17. Microscale Patterning of Thermoplastic Polymer Surfaces by Selective Solvent Swelling

    PubMed Central

    Rahmanian, Omid; Chen, Chien-Fu; DeVoe, Don L.

    2012-01-01

    A new method for the fabrication of microscale features in thermoplastic substrates is presented. Unlike traditional thermoplastic microfabrication techniques, in which bulk polymer is displaced from the substrate by machining or embossing, a unique process termed orogenic microfabrication has been developed in which selected regions of a thermoplastic surface are raised from the substrate by an irreversible solvent swelling mechanism. The orogenic technique allows thermoplastic surfaces to be patterned using a variety of masking methods, resulting in three-dimensional features that would be difficult to achieve through traditional microfabrication methods. Using cyclic olefin copolymer as a model thermoplastic material, several variations of this process are described to realize growth heights ranging from several nanometers to tens of microns, with patterning techniques include direct photoresist masking, patterned UV/ozone surface passivation, elastomeric stamping, and noncontact spotting. Orogenic microfabrication is also demonstrated by direct inkjet printing as a facile photolithography-free masking method for rapid desktop thermoplastic microfabrication. PMID:22900539

  18. Minimization of the environmental impact of chrome tanning: a new process with high chrome exhaustion.

    PubMed

    Morera, Josep M; Bacardit, Anna; Ollé, Lluís; Bartolí, Esther; Borràs, Maria D

    2007-11-01

    In all tanning technology operations wastes are generated. These reach the environment as residual waters, solid and liquid waste as well as atmospheric emissions and odours. This study tests an alternative method to the traditional tanning method at an industrial level. The new method is based on tanning without float and by significantly increasing the temperature at the end of the tanning process. The properties of the leathers obtained using the two methods have been compared and the results indicate that those leathers have similar physical, chemical, and organoleptic properties. However, the differences existing from the environmental point of view are significant. It is not necessary to use clean water for this tanning. Moreover, there is a 75% reduction of the residual float, a 91% reduction of the chrome discharged, and a 94% reduction of the chlorides discharged. A financial assessment was carried out to demonstrate that the newly proposed system is 32% more economic than the traditional one.

  19. Multidimensional upwind hydrodynamics on unstructured meshes using graphics processing units - I. Two-dimensional uniform meshes

    NASA Astrophysics Data System (ADS)

    Paardekooper, S.-J.

    2017-08-01

    We present a new method for numerical hydrodynamics which uses a multidimensional generalization of the Roe solver and operates on an unstructured triangular mesh. The main advantage over traditional methods based on Riemann solvers, which commonly use one-dimensional flux estimates as building blocks for a multidimensional integration, is its inherently multidimensional nature, and as a consequence its ability to recognize multidimensional stationary states that are not hydrostatic. A second novelty is the focus on graphics processing units (GPUs). By tailoring the algorithms specifically to GPUs, we are able to get speedups of 100-250 compared to a desktop machine. We compare the multidimensional upwind scheme to a traditional, dimensionally split implementation of the Roe solver on several test problems, and we find that the new method significantly outperforms the Roe solver in almost all cases. This comes with increased computational costs per time-step, which makes the new method approximately a factor of 2 slower than a dimensionally split scheme acting on a structured grid.

  20. Effect of raw materials and hardening process on hardness of manually forged knife

    NASA Astrophysics Data System (ADS)

    Balkhaya, Suwarno

    2017-06-01

    Knives are normally made by forging process either using a machine or traditional method by means of hammering process. This present work was conducted to study the effects of steel raw materials and hardening process on the hardness of manually forged knives. The knife samples were made by traditional hammering (forging) process done by local blacksmith. Afterward, the samples were heat treated with two different hardening procedures, the first was based on the blacksmith procedure and the second was systematically done at the laboratory. The forging was done in the temperature ranged between 900-950°C, while the final temperature ranged between 650-675°C. The results showed that knives made of spring steel and heat treated in simulated condition at the laboratory obtained higher level of hardness, i.e. 62 HRC. In general, knives heat treated by local blacksmith had lower level of hardness that those obtained from simulated condition. Therefore, we concluded that the traditional knife quality in term of hardness can be improved by optimizing the heat treatment schedule.

  1. Microwave-Assisted Hydro-Distillation of Essential Oil from Rosemary: Comparison with Traditional Distillation

    PubMed Central

    Moradi, Sara; Fazlali, Alireza; Hamedi, Hamid

    Background: Hydro-distillation (HD) method is a traditional technique which is used in most industrial companies. Microwave-assisted Hydro-distillation (MAHD) is an advanced HD technique utilizing a microwave oven in the extraction process. Methods: In this research, MAHD of essential oils from the aerial parts (leaves) of rosemary (Rosmarinus officinalis L.) was studied and the results were compared with those of the conventional HD in terms of extraction time, extraction efficiency, chemical composition, quality of the essential oils and cost of the operation. Results: Microwave hydro-distillation was superior in terms of saving energy and extraction time (30 min, compared to 90 min in HD). Chromatography was used for quantity analysis of the essential oils composition. Quality of essential oil improved in MAHD method due to an increase of 17% in oxygenated compounds. Conclusion: Consequently, microwave hydro-distillation can be used as a substitute of traditional hydro-distillation. PMID:29296263

  2. An AK-LDMeans algorithm based on image clustering

    NASA Astrophysics Data System (ADS)

    Chen, Huimin; Li, Xingwei; Zhang, Yongbin; Chen, Nan

    2018-03-01

    Clustering is an effective analytical technique for handling unmarked data for value mining. Its ultimate goal is to mark unclassified data quickly and correctly. We use the roadmap for the current image processing as the experimental background. In this paper, we propose an AK-LDMeans algorithm to automatically lock the K value by designing the Kcost fold line, and then use the long-distance high-density method to select the clustering centers to further replace the traditional initial clustering center selection method, which further improves the efficiency and accuracy of the traditional K-Means Algorithm. And the experimental results are compared with the current clustering algorithm and the results are obtained. The algorithm can provide effective reference value in the fields of image processing, machine vision and data mining.

  3. Traditional learning and problem-based learning: self-perception of preparedness for internship.

    PubMed

    Millan, Laís Pereira Bueno; Semer, Beatriz; Rodrigues, José Mauro da Silva; Gianini, Reinaldo José

    2012-01-01

    This study aims to evaluate Pontificia Universidade Católica de São Paulo (PUC-SP) medical students' perception of their preparedness to attend the internship course by comparing students who entered the internship in 2009, who were taught according to the traditional learning method, and those who entered the internship in 2010, who were taught according to the new method, i.e. problem-based learning (PBL). 50 traditional learning method students answered a standard Lickert scale questionnaire upon entering internship in 2009. In 2010, the process was repeated with PBL students. The questionnaire was based upon the Preparation for Hospital Practice Questionnaire. This questionnaire was evaluated by professors from three medical schools in Brazil regarding its applicability. The original questions were classified according to the importance these professors attributed to them, and less important questions were removed. Scores obtained from the Student's t-test were considered significant with p < 0.05. A significant statistical difference was observed in 16 questions, and the traditional learning method students reported higher average scores. When questions were divided into dimensions, a significant statistical difference appeared in the dimensions " social aspects of health", "medical skills", and "ethical concepts"; traditional learning method students again reported higher scores (p < 0.001 for all dimensions). Higher scores were also reported when the average of the answers to the whole questionnaire was calculated. Traditional learning method students consider themselves to be better prepared for internship activities than PBL students, according to the following three comparative means: by analyzing the answers to each question, by grouping these answers into dimensions, and by calculating the means of answers to the whole questionnaire.

  4. Cochrane Qualitative and Implementation Methods Group guidance series-paper 5: methods for integrating qualitative and implementation evidence within intervention effectiveness reviews.

    PubMed

    Harden, Angela; Thomas, James; Cargo, Margaret; Harris, Janet; Pantoja, Tomas; Flemming, Kate; Booth, Andrew; Garside, Ruth; Hannes, Karin; Noyes, Jane

    2018-05-01

    The Cochrane Qualitative and Implementation Methods Group develops and publishes guidance on the synthesis of qualitative and mixed-method evidence from process evaluations. Despite a proliferation of methods for the synthesis of qualitative research, less attention has focused on how to integrate these syntheses within intervention effectiveness reviews. In this article, we report updated guidance from the group on approaches, methods, and tools, which can be used to integrate the findings from quantitative studies evaluating intervention effectiveness with those from qualitative studies and process evaluations. We draw on conceptual analyses of mixed methods systematic review designs and the range of methods and tools that have been used in published reviews that have successfully integrated different types of evidence. We outline five key methods and tools as devices for integration which vary in terms of the levels at which integration takes place; the specialist skills and expertise required within the review team; and their appropriateness in the context of limited evidence. In situations where the requirement is the integration of qualitative and process evidence within intervention effectiveness reviews, we recommend the use of a sequential approach. Here, evidence from each tradition is synthesized separately using methods consistent with each tradition before integration takes place using a common framework. Reviews which integrate qualitative and process evaluation evidence alongside quantitative evidence on intervention effectiveness in a systematic way are rare. This guidance aims to support review teams to achieve integration and we encourage further development through reflection and formal testing. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Visible Light Responsive Liquid Crystal Polymers Containing Reactive Moieties with Good Processability.

    PubMed

    Liu, Yuyun; Wu, Wei; Wei, Jia; Yu, Yanlei

    2017-01-11

    Two types of novel reactive linear liquid crystal polymers (LLCPs) with different azotolene concentrations have been synthesized and processed into films and fibers by solution and melting processing methods. Then, the LLCPs in the obtained monodomain fiber and polydomain film were easily cross-linked with difunctional primary amines. The resulted cross-linked liquid crystal polymers (CLCPs) underwent reversible photoinduced bending and unbending behaviors in response to 445 and 530 nm visible light at room temperature, respectively. The post-cross-linking method provides a facile way to prepare the CLCP films and fibers with different shapes from LLCPs, which can be processed by traditional melting and solution methods.

  6. The Arrangement of Students' Extracurricular Piano Practice Process with the Asynchronous Distance Piano Teaching Method

    ERIC Educational Resources Information Center

    Karahan, Ahmet Suat

    2015-01-01

    That the students do their extracurricular piano practices in the direction of the teacher's warnings is a key factor in achieving success in the teaching-learning process. However, the teachers cannot adequately control the students' extracurricular practices in the process of traditional piano education. Under the influence of this lack of…

  7. Process-Driven Math: An Auditory Method of Mathematics Instruction and Assessment for Students Who Are Blind or Have Low Vision

    ERIC Educational Resources Information Center

    Gulley, Ann P.; Smith, Luke A.; Price, Jordan A.; Prickett, Logan C.; Ragland, Matthew F.

    2017-01-01

    Process-Driven Math is a fully audio method of mathematics instruction and assessment that was created at Auburn University at Montgomery, Alabama, to meet the needs of one particular student, Logan. He was blind, mobility impaired, and he could not speak above a whisper. Logan was not able to use traditional low vision tools like braille and…

  8. Low-temperature technique for thick film resist stabilization and curing

    NASA Astrophysics Data System (ADS)

    Minter, Jason P.; Wong, Selmer S.; Marlowe, Trey; Ross, Matthew F.; Narcy, Mark E.; Livesay, William R.

    1999-06-01

    For a range of thick film photoresist applications, including MeV ion implant processing, thin film head manufacturing, and microelectromechanical systems processing, there is a need for a low-temperature method for resist stabilization and curing. Traditional methods of stabilizing or curing resist films have relied on thermal cycling, which may not be desirable due to device temperature limitations or thermally-induced distortion of the resist features.

  9. Multi-parameters monitoring during traditional Chinese medicine concentration process with near infrared spectroscopy and chemometrics

    NASA Astrophysics Data System (ADS)

    Liu, Ronghua; Sun, Qiaofeng; Hu, Tian; Li, Lian; Nie, Lei; Wang, Jiayue; Zhou, Wanhui; Zang, Hengchang

    2018-03-01

    As a powerful process analytical technology (PAT) tool, near infrared (NIR) spectroscopy has been widely used in real-time monitoring. In this study, NIR spectroscopy was applied to monitor multi-parameters of traditional Chinese medicine (TCM) Shenzhiling oral liquid during the concentration process to guarantee the quality of products. Five lab scale batches were employed to construct quantitative models to determine five chemical ingredients and physical change (samples density) during concentration process. The paeoniflorin, albiflorin, liquiritin and samples density were modeled by partial least square regression (PLSR), while the content of the glycyrrhizic acid and cinnamic acid were modeled by support vector machine regression (SVMR). Standard normal variate (SNV) and/or Savitzkye-Golay (SG) smoothing with derivative methods were adopted for spectra pretreatment. Variable selection methods including correlation coefficient (CC), competitive adaptive reweighted sampling (CARS) and interval partial least squares regression (iPLS) were performed for optimizing the models. The results indicated that NIR spectroscopy was an effective tool to successfully monitoring the concentration process of Shenzhiling oral liquid.

  10. The efficacy of a continuous quality improvement (CQI) method in a radiological department. Comparison with non-CQI control material.

    PubMed

    Laurila, J; Standertskjöld-Nordenstam, C G; Suramo, I; Tolppanen, E M; Tervonen, O; Korhola, O; Brommels, M

    2001-01-01

    To study the efficacy of continuous quality improvement (CQI) compared to ordinary management in an on-duty radiology department. Because of complaints regarding delivery of on-duty radiological services, an improvement was initiated simultaneously at two hospitals, at the HUCH (Helsinki University Central Hospital) utilising the CQI-method, and at the OUH (Oulu University Hospital) with a traditional management process. For the CQI project, a team was formed to evaluate the process with flow-charts, cause and effect diagrams, Pareto analysis and control charts. Interventions to improve the process were based on the results of these analyses. The team at the HUCH implemented the following changes: A radiologist was added to the evening shift between 15:00-22:00 and a radiographer was moved from the morning shift to 15:00-22:00. A clear improvement was achieved in the turn-around time, but in the follow-up some of the gains were lost. Only minimal changes were achieved at the OUH, where the intervention was based on traditional management processes. CQI was an effective method for improving the quality of performance of a radiology department compared with ordinary management methods, but some of this improvement may be subsequently lost without a continuous measurement system.

  11. Near-infrared Spectroscopy as a Process Analytical Technology Tool for Monitoring the Parching Process of Traditional Chinese Medicine Based on Two Kinds of Chemical Indicators.

    PubMed

    Li, Kaiyue; Wang, Weiying; Liu, Yanping; Jiang, Su; Huang, Guo; Ye, Liming

    2017-01-01

    The active ingredients and thus pharmacological efficacy of traditional Chinese medicine (TCM) at different degrees of parching process vary greatly. Near-infrared spectroscopy (NIR) was used to develop a new method for rapid online analysis of TCM parching process, using two kinds of chemical indicators (5-(hydroxymethyl) furfural [5-HMF] content and 420 nm absorbance) as reference values which were obviously observed and changed in most TCM parching process. Three representative TCMs, Areca ( Areca catechu L.), Malt ( Hordeum Vulgare L.), and Hawthorn ( Crataegus pinnatifida Bge.), were used in this study. With partial least squares regression, calibration models of NIR were generated based on two kinds of reference values, i.e. 5-HMF contents measured by high-performance liquid chromatography (HPLC) and 420 nm absorbance measured by ultraviolet-visible spectroscopy (UV/Vis), respectively. In the optimized models for 5-HMF, the root mean square errors of prediction (RMSEP) for Areca, Malt, and Hawthorn was 0.0192, 0.0301, and 0.2600 and correlation coefficients ( R cal ) were 99.86%, 99.88%, and 99.88%, respectively. Moreover, in the optimized models using 420 nm absorbance as reference values, the RMSEP for Areca, Malt, and Hawthorn was 0.0229, 0.0096, and 0.0409 and R cal were 99.69%, 99.81%, and 99.62%, respectively. NIR models with 5-HMF content and 420 nm absorbance as reference values can rapidly and effectively identify three kinds of TCM in different parching processes. This method has great promise to replace current subjective color judgment and time-consuming HPLC or UV/Vis methods and is suitable for rapid online analysis and quality control in TCM industrial manufacturing process. Near-infrared spectroscopy.(NIR) was used to develop a new method for online analysis of traditional Chinese medicine.(TCM) parching processCalibration and validation models of Areca, Malt, and Hawthorn were generated by partial least squares regression using 5.(hydroxymethyl) furfural contents and 420.nm absorbance as reference values, respectively, which were main indicator components during parching process of most TCMThe established NIR models of three TCMs had low root mean square errors of prediction and high correlation coefficientsThe NIR method has great promise for use in TCM industrial manufacturing processes for rapid online analysis and quality control. Abbreviations used: NIR: Near-infrared Spectroscopy; TCM: Traditional Chinese medicine; Areca: Areca catechu L.; Hawthorn: Crataegus pinnatifida Bge.; Malt: Hordeum vulgare L.; 5-HMF: 5-(hydroxymethyl) furfural; PLS: Partial least squares; D: Dimension faction; SLS: Straight line subtraction, MSC: Multiplicative scatter correction; VN: Vector normalization; RMSECV: Root mean square errors of cross-validation; RMSEP: Root mean square errors of validation; R cal : Correlation coefficients; RPD: Residual predictive deviation; PAT: Process analytical technology; FDA: Food and Drug Administration; ICH: International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use.

  12. A Quadrupole Dalton-based multi-attribute method for product characterization, process development, and quality control of therapeutic proteins.

    PubMed

    Xu, Weichen; Jimenez, Rod Brian; Mowery, Rachel; Luo, Haibin; Cao, Mingyan; Agarwal, Nitin; Ramos, Irina; Wang, Xiangyang; Wang, Jihong

    2017-10-01

    During manufacturing and storage process, therapeutic proteins are subject to various post-translational modifications (PTMs), such as isomerization, deamidation, oxidation, disulfide bond modifications and glycosylation. Certain PTMs may affect bioactivity, stability or pharmacokinetics and pharmacodynamics profile and are therefore classified as potential critical quality attributes (pCQAs). Identifying, monitoring and controlling these PTMs are usually key elements of the Quality by Design (QbD) approach. Traditionally, multiple analytical methods are utilized for these purposes, which is time consuming and costly. In recent years, multi-attribute monitoring methods have been developed in the biopharmaceutical industry. However, these methods combine high-end mass spectrometry with complicated data analysis software, which could pose difficulty when implementing in a quality control (QC) environment. Here we report a multi-attribute method (MAM) using a Quadrupole Dalton (QDa) mass detector to selectively monitor and quantitate PTMs in a therapeutic monoclonal antibody. The result output from the QDa-based MAM is straightforward and automatic. Evaluation results indicate this method provides comparable results to the traditional assays. To ensure future application in the QC environment, this method was qualified according to the International Conference on Harmonization (ICH) guideline and applied in the characterization of drug substance and stability samples. The QDa-based MAM is shown to be an extremely useful tool for product and process characterization studies that facilitates facile understanding of process impact on multiple quality attributes, while being QC friendly and cost-effective.

  13. A novel calibration method for non-orthogonal shaft laser theodolite measurement system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wu, Bin, E-mail: wubin@tju.edu.cn, E-mail: xueting@tju.edu.cn; Yang, Fengting; Ding, Wen

    2016-03-15

    Non-orthogonal shaft laser theodolite (N-theodolite) is a new kind of large-scale metrological instrument made up by two rotary tables and one collimated laser. There are three axes for an N-theodolite. According to naming conventions in traditional theodolite, rotary axes of two rotary tables are called as horizontal axis and vertical axis, respectively, and the collimated laser beam is named as sight axis. And the difference between N-theodolite and traditional theodolite is obvious, since the former one with no orthogonal and intersecting accuracy requirements. So the calibration method for traditional theodolite is no longer suitable for N-theodolite, while the calibration methodmore » applied currently is really complicated. Thus this paper introduces a novel calibration method for non-orthogonal shaft laser theodolite measurement system to simplify the procedure and to improve the calibration accuracy. A simple two-step process, calibration for intrinsic parameters and for extrinsic parameters, is proposed by the novel method. And experiments have shown its efficiency and accuracy.« less

  14. Ethnobotany in Traditional Ceremony at Kanagarian Sontang Cubadak Padang Gelugur Subdistrict, Pasaman District

    NASA Astrophysics Data System (ADS)

    Des, M.; Rizki, R.; Hidayati, H.

    2018-04-01

    Kanagarian Sontang Cubadak has two distinct customary cultures namely Minang and Mandailing customs. Each costum has a sequence of processions performed on the customs of marriage, birth, coronation of community elders, the events of new society, salvation and death. In the implementation of the community using plants in the ceremonial procession of the ceremony. To know the types, meanings and ways of using plants in this traditional ceremony, conduct ethnobotany research on traditional ceremonies of marriage, birth, and death. Research conducted in May - June 2016 in Kanagarian Sontang Cubadak Padang Gelugur Subdistrict, Pasaman District, West Sumatra, Indonesia. Sampling using descriptive survey method, by interviewing village elders and the community. The sample identification was done in the botanical laboratory of Universitas Negeri Padang and STKIP PGRI West Sumatra. The results obtained 30 species from 19 family. In the Minang tribe ceremony found 16 species of 10 family, while in the Mandailing tribe 26 species of 18 family. Utilization of plants that eventually found in species Oryza sativa L. with a benefit value of 0.56. The meaning of plants in traditional ceremonies, relationships kinship, related social relations, related prayers and related aesthetics. The use of plants in traditional ceremonies is used in a raw state and some are processed before use.

  15. Recent advances in the reconstruction of cranio-maxillofacial defects using computer-aided design/computer-aided manufacturing.

    PubMed

    Oh, Ji-Hyeon

    2018-12-01

    With the development of computer-aided design/computer-aided manufacturing (CAD/CAM) technology, it has been possible to reconstruct the cranio-maxillofacial defect with more accurate preoperative planning, precise patient-specific implants (PSIs), and shorter operation times. The manufacturing processes include subtractive manufacturing and additive manufacturing and should be selected in consideration of the material type, available technology, post-processing, accuracy, lead time, properties, and surface quality. Materials such as titanium, polyethylene, polyetheretherketone (PEEK), hydroxyapatite (HA), poly-DL-lactic acid (PDLLA), polylactide-co-glycolide acid (PLGA), and calcium phosphate are used. Design methods for the reconstruction of cranio-maxillofacial defects include the use of a pre-operative model printed with pre-operative data, printing a cutting guide or template after virtual surgery, a model after virtual surgery printed with reconstructed data using a mirror image, and manufacturing PSIs by directly obtaining PSI data after reconstruction using a mirror image. By selecting the appropriate design method, manufacturing process, and implant material according to the case, it is possible to obtain a more accurate surgical procedure, reduced operation time, the prevention of various complications that can occur using the traditional method, and predictive results compared to the traditional method.

  16. The importance of activity-based methods in radiology and the technology that now makes this possible.

    PubMed

    Monge, Paul

    2006-01-01

    Activity-based methods serve as a dynamic process that has allowed many other industries to reduce and control their costs, increase productivity, and streamline their processes while improving product quality and service. The method could serve the healthcare industry in an equally beneficial way. Activity-based methods encompass both activity based costing (ABC) and activity-based management (ABM). ABC is a cost management approach that links resource consumption to activities that an enterprise performs, and then assigns those activities and their associated costs to customers, products, or product lines. ABM uses the resource assignments derived in ABC so that operation managers can improve their departmental processes and workflows. There are three fundamental problems with traditional cost systems. First, traditional systems fail to reflect the underlying diversity of work taking place within an enterprise. Second, it uses allocations that are, for the most part, arbitrary Single step allocations fail to reflect the real work-the activities being performed and the associate resources actually consumed. Third, they only provide a cost number that, standing alone, does not provide any guidance on how to improve performance by lowering cost or enhancing throughput.

  17. The Distinctive Vocation of Business Education in Catholic Universities

    ERIC Educational Resources Information Center

    Goodpaster, Kenneth E.; Maines, T. Dean

    2012-01-01

    Catholic business schools need a process to shape their operations intentionally in light of the Catholic moral tradition. Recent developments in Catholic health care suggest a model they might follow. This model uses a method known as the "Self-Assessment and Improvement Process" (SAIP), which helps leaders deploy moral principles…

  18. Hands-On Hydroponics

    ERIC Educational Resources Information Center

    Carver, Jeffrey; Wasserman, Bradley

    2012-01-01

    Hydroponics is a process in which plants are grown using nutrient-rich water instead of soil. Because this process maximizes the use of water and nutrients--providing only what the plant uses in controlled and easily maintained systems--it is a viable alternative to traditional farming methods. The amount of control in these systems also ensures…

  19. Evaluation of Models of the Reading Process.

    ERIC Educational Resources Information Center

    Balajthy, Ernest

    A variety of reading process models have been proposed and evaluated in reading research. Traditional approaches to model evaluation specify the workings of a system in a simplified fashion to enable organized, systematic study of the system's components. Following are several statistical methods of model evaluation: (1) empirical research on…

  20. A one pot organic/CdSe nanoparticle hybrid material synthesis with in situ π-conjugated ligand functionalization.

    PubMed

    Mazzio, Katherine A; Okamoto, Ken; Li, Zhi; Gutmann, Sebastian; Strein, Elisabeth; Ginger, David S; Schlaf, Rudy; Luscombe, Christine K

    2013-02-14

    A one pot method for organic/colloidal CdSe nanoparticle hybrid material synthesis is presented. Relative to traditional ligand exchange processes, these materials require smaller amounts of the desired capping ligand, shorter syntheses and fewer processing steps, while maintaining nanoparticle morphology.

  1. Law Firm: A First-Year Course on Lawyering.

    ERIC Educational Resources Information Center

    Braveman, Daan

    1989-01-01

    An experimental first-year course introducing law students to the law firm addressed: a single issue in contract law from both sides, writing as an advocate, the lawyer's role, legal research methods, the legislative process, the counseling function, the appellate process, and traditional legal writing. An interdisciplinary approach was used. (MSE)

  2. Using Teacher Effectiveness Data for Information-Rich Hiring

    ERIC Educational Resources Information Center

    Cannata, Marisa; Rubin, Mollie; Goldring, Ellen; Grissom, Jason A.; Neumerski, Christine M.; Drake, Timothy A.; Schuermann, Patrick

    2017-01-01

    Purpose: New teacher effectiveness measures have the potential to influence how principals hire teachers as they provide new and richer information about candidates to a traditionally information-poor process. This article examines how the hiring process is changing as a result of teacher evaluation reforms. Research Methods: Data come from…

  3. An efficient nontraditional method of directly converting a cotton fibrous material into a woven-like hydroentangled nonwoven cotton fabric

    USDA-ARS?s Scientific Manuscript database

    The traditional technology of producing cotton woven fabrics is comprised of about 20 mechanical and chemical processes that generally are costly, slow, inefficient, and environmentally somewhat unfriendly. A modern system, using fewer preparatory processes, of fabricating hydro-entangled cotton and...

  4. Traditional cheeses: rich and diverse microbiota with associated benefits.

    PubMed

    Montel, Marie-Christine; Buchin, Solange; Mallet, Adrien; Delbes-Paus, Céline; Vuitton, Dominique A; Desmasures, Nathalie; Berthier, Françoise

    2014-05-02

    The risks and benefits of traditional cheeses, mainly raw milk cheeses, are rarely set out objectively, whence the recurrent confused debate over their pros and cons. This review starts by emphasizing the particularities of the microbiota in traditional cheeses. It then describes the sensory, hygiene, and possible health benefits associated with traditional cheeses. The microbial diversity underlying the benefits of raw milk cheese depends on both the milk microbiota and on traditional practices, including inoculation practices. Traditional know-how from farming to cheese processing helps to maintain both the richness of the microbiota in individual cheeses and the diversity between cheeses throughout processing. All in all more than 400 species of lactic acid bacteria, Gram and catalase-positive bacteria, Gram-negative bacteria, yeasts and moulds have been detected in raw milk. This biodiversity decreases in cheese cores, where a small number of lactic acid bacteria species are numerically dominant, but persists on the cheese surfaces, which harbour numerous species of bacteria, yeasts and moulds. Diversity between cheeses is due particularly to wide variations in the dynamics of the same species in different cheeses. Flavour is more intense and rich in raw milk cheeses than in processed ones. This is mainly because an abundant native microbiota can express in raw milk cheeses, which is not the case in cheeses made from pasteurized or microfiltered milk. Compared to commercial strains, indigenous lactic acid bacteria isolated from milk/cheese, and surface bacteria and yeasts isolated from traditional brines, were associated with more complex volatile profiles and higher scores for some sensorial attributes. The ability of traditional cheeses to combat pathogens is related more to native antipathogenic strains or microbial consortia than to natural non-microbial inhibitor(s) from milk. Quite different native microbiota can protect against Listeria monocytogenes in cheeses (in both core and surface) and on the wooden surfaces of traditional equipment. The inhibition seems to be associated with their qualitative and quantitative composition rather than with their degree of diversity. The inhibitory mechanisms are not well elucidated. Both cross-sectional and cohort studies have evidenced a strong association of raw-milk consumption with protection against allergic/atopic diseases; further studies are needed to determine whether such association extends to traditional raw-milk cheese consumption. In the future, the use of meta-omics methods should help to decipher how traditional cheese ecosystems form and function, opening the way to new methods of risk-benefit management from farm to ripened cheese. Published by Elsevier B.V.

  5. Evaluation of Team-Based Learning and Traditional Instruction in Teaching Removable Partial Denture Concepts.

    PubMed

    Echeto, Luisa F; Sposetti, Venita; Childs, Gail; Aguilar, Maria L; Behar-Horenstein, Linda S; Rueda, Luis; Nimmo, Arthur

    2015-09-01

    The aim of this study was to evaluate the effectiveness of team-based learning (TBL) methodology on dental students' retention of knowledge regarding removable partial denture (RPD) treatment. The process of learning RPD treatment requires that students first acquire foundational knowledge and then use critical thinking skills to apply that knowledge to a variety of clinical situations. The traditional approach to teaching, characterized by a reliance on lectures, is not the most effective method for learning clinical applications. To address the limitations of that approach, the teaching methodology of the RPD preclinical course at the University of Florida was changed to TBL, which has been shown to motivate student learning and improve clinical performance. A written examination was constructed to compare the impact of TBL with that of traditional teaching regarding students' retention of knowledge and their ability to evaluate, diagnose, and treatment plan a partially edentulous patient with an RPD prosthesis. Students taught using traditional and TBL methods took the same examination. The response rate (those who completed the examination) for the class of 2013 (traditional method) was 94% (79 students of 84); for the class of 2014 (TBL method), it was 95% (78 students of 82). The results showed that students who learned RPD with TBL scored higher on the examination than those who learned RPD with traditional methods. Compared to the students taught with the traditional method, the TBL students' proportion of passing grades was statistically significantly higher (p=0.002), and 23.7% more TBL students passed the examination. The mean score for the TBL class (0.758) compared to the conventional class (0.700) was statistically significant with a large effect size, also demonstrating the practical significance of the findings. The results of the study suggest that TBL methodology is a promising approach to teaching RPD with successful outcomes.

  6. Alternative contracting research : final report.

    DOT National Transportation Integrated Search

    2016-08-01

    Alternative contracting methods have become popular alternatives to the traditional practice whose emphasis is on low bid acquisition. The benefits of decreased project schedule, increased job quality, and improved delivery process have demonstrated ...

  7. Managing change in the nursing handover from traditional to bedside handover – a case study from Mauritius

    PubMed Central

    Kassean, Hemant K; Jagoo, Zaheda B

    2005-01-01

    Background The shift handover forms an important part of the communication process that takes place twice within the nurses' working day in the gynaecological ward. This paper addresses the topic of implementing a new system of bedside handover, which puts patients central to the whole process of managing care and also addresses some of the shortcomings of the traditional handover system. Methods A force field analysis in terms of the driving forces had shown that there was dissatisfaction with the traditional method of handover which had led to an increase in the number of critical incidents and complaints from patients, relatives and doctors. The restraining forces identified were a fear of accountability, lack of confidence and that this change would lead to more work. A 3 – step planned change model consisting of unfreezing, moving and refreezing was used to guide us through the change process. Resistance to change was managed by creating a climate of open communication where stakeholders were allowed to voice opinions, share concerns, insights, and ideas thereby actively participating in decision making. Results An evaluation had shown that this process was successfully implemented to the satisfaction of patients, and staff in general. Conclusion This successful change should encourage other nurses to become more proactive in identifying areas for change management in order to improve our health care system. PMID:15676078

  8. [Effect of sand-stabilization engineering on soil humus and components by analysis by several spectroscopy methods].

    PubMed

    Zhang, Yu-lan; Sun, Cai-xia; Duan, Zheng-hu; Chen, Li-jun; Wu, Zhi-jie; Chen, Xiao-hong; Zhang, Ai-ming; Liu, Xing-bin; Wang, Jun-yu

    2010-01-01

    After the potassium bichromate-strong sulfuric acid hot process, the ultraviolet spectrophotometer was used on the contrast with the traditional titrimetric method to analyze soil (51 years, 43 year, 32 year, 20 year vegetations restores in the Tenggeli sand) humus and the humus components content. At the same time, the infrared spectrum was used to discuss their structure change during restoring process. The result indicated that using the visible spectroscopy method for the determination of the humus and the humus component is feasible. The spectroscopy method determination of organic matter is better (coefficient of variation at most is 7.26%) than the traditional titrimetric method, as it is accurate, fast and simple, and favors large quantities. The result indicated that humus content presents increasing tendency along with restoring ages. Change is big in early restore time, and tends to be stable in the later period. Infrared spectrum shape is similar, but the characteristic peak intensity has obvious difference. Compared with the wind-drift sand, little molecule saccharides decrease and aryl-groups increase.

  9. Improving runoff risk estimates: Formulating runoff as a bivariate process using the SCS curve number method

    NASA Astrophysics Data System (ADS)

    Shaw, Stephen B.; Walter, M. Todd

    2009-03-01

    The Soil Conservation Service curve number (SCS-CN) method is widely used to predict storm runoff for hydraulic design purposes, such as sizing culverts and detention basins. As traditionally used, the probability of calculated runoff is equated to the probability of the causative rainfall event, an assumption that fails to account for the influence of variations in soil moisture on runoff generation. We propose a modification to the SCS-CN method that explicitly incorporates rainfall return periods and the frequency of different soil moisture states to quantify storm runoff risks. Soil moisture status is assumed to be correlated to stream base flow. Fundamentally, this approach treats runoff as the outcome of a bivariate process instead of dictating a 1:1 relationship between causative rainfall and resulting runoff volumes. Using data from the Fall Creek watershed in western New York and the headwaters of the French Broad River in the mountains of North Carolina, we show that our modified SCS-CN method improves frequency discharge predictions in medium-sized watersheds in the eastern United States in comparison to the traditional application of the method.

  10. Computational Process Modeling for Additive Manufacturing (OSU)

    NASA Technical Reports Server (NTRS)

    Bagg, Stacey; Zhang, Wei

    2015-01-01

    Powder-Bed Additive Manufacturing (AM) through Direct Metal Laser Sintering (DMLS) or Selective Laser Melting (SLM) is being used by NASA and the Aerospace industry to "print" parts that traditionally are very complex, high cost, or long schedule lead items. The process spreads a thin layer of metal powder over a build platform, then melts the powder in a series of welds in a desired shape. The next layer of powder is applied, and the process is repeated until layer-by-layer, a very complex part can be built. This reduces cost and schedule by eliminating very complex tooling and processes traditionally used in aerospace component manufacturing. To use the process to print end-use items, NASA seeks to understand SLM material well enough to develop a method of qualifying parts for space flight operation. Traditionally, a new material process takes many years and high investment to generate statistical databases and experiential knowledge, but computational modeling can truncate the schedule and cost -many experiments can be run quickly in a model, which would take years and a high material cost to run empirically. This project seeks to optimize material build parameters with reduced time and cost through modeling.

  11. Rational Choice or Leap of Faith? The Creation and Defence of a Management Orthodoxy

    ERIC Educational Resources Information Center

    Oliver, Nick

    2008-01-01

    Purpose: In the 1980s and 1990s enthusiasm for Japanese or "lean" manufacturing methods swept through Western industry. At the time, commentators argued that these methods represented a new paradigm of manufacturing, a radical break with traditional methods. The purpose of this paper is to explore the process of conversion from one…

  12. Implementation and Evaluation of Flipped Classroom as IoT Element into Learning Process of Computer Network Education

    ERIC Educational Resources Information Center

    Zhamanov, Azamat; Yoo, Seong-Moo; Sakhiyeva, Zhulduz; Zhaparov, Meirambek

    2018-01-01

    Students nowadays are hard to be motivated to study lessons with traditional teaching methods. Computers, smartphones, tablets and other smart devices disturb students' attentions. Nevertheless, those smart devices can be used as auxiliary tools of modern teaching methods. In this article, the authors review two popular modern teaching methods:…

  13. Optimization technique for rolled edge control process based on the acentric tool influence functions.

    PubMed

    Du, Hang; Song, Ci; Li, Shengyi; Xu, Mingjin; Peng, Xiaoqiang

    2017-05-20

    In the process of computer controlled optical surfacing (CCOS), the uncontrollable rolled edge restricts further improvements of the machining accuracy and efficiency. Two reasons are responsible for the rolled edge problem during small tool polishing. One is that the edge areas cannot be processed because of the orbit movement. The other is that changing the tool influence function (TIF) is difficult to compensate for in algorithms, since pressure step appears in the local pressure distribution at the surface edge. In this paper, an acentric tool influence function (A-TIF) is designed to remove the rolled edge after CCOS polishing. The model of A-TIF is analyzed theoretically, and a control point translation dwell time algorithm is used to verify that the full aperture of the workpiece can be covered by the peak removal point of the tool influence functions. Thus, surface residual error in the full aperture can be effectively corrected. Finally, the experiments are carried out. Two fused silica glass samples of 100  mm×100  mm are polished by traditional CCOS and the A-TIF method, respectively. The rolled edge was clearly produced in the sample polished by the traditional CCOS, while residual errors do not show this problem the sample polished by the A-TIF method. Therefore, the rolled edge caused by the traditional CCOS process is successfully suppressed during the A-TIF process. The ability to suppress the rolled edge of the designed A-TIF has been confirmed.

  14. Expanding the printable design space for lithography processes utilizing a cut mask

    NASA Astrophysics Data System (ADS)

    Wandell, Jerome; Salama, Mohamed; Wilkinson, William; Curtice, Mark; Feng, Jui-Hsuan; Gao, Shao Wen; Asthana, Abhishek

    2016-03-01

    The utilization of a cut-mask in semiconductor patterning processes has been in practice for logic devices since the inception of 32nm-node devices, notably with unidirectional gate level printing. However, the microprocessor applications where cut-mask patterning methods are used are expanding as Self-Aligned Double Patterning (SADP) processes become mainstream for 22/14nm fin diffusion, and sub-14nm metal levels. One common weakness for these types of lithography processes is that the initial pattern requiring the follow-up cut-mask typically uses an extreme off-axis imaging source such as dipole to enhance the resolution and line-width roughness (LWR) for critical dense patterns. This source condition suffers from poor process margin in the semi-dense (forbidden pitch) realm and wrong-way directional design spaces. Common pattern failures in these limited design regions include bridging and extra-printing defects that are difficult to resolve with traditional mask improvement means. This forces the device maker to limit the allowable geometries that a designer may use on a device layer. This paper will demonstrate methods to expand the usable design space on dipole-like processes such as unidirectional gate and SADP processes by utilizing the follow-up cut mask to improve the process window. Traditional mask enhancement means for improving the process window in this design realm will be compared to this new cut-mask approach. The unique advantages and disadvantages of the cut-mask solution will be discussed in contrast to those customary methods.

  15. Pre-analytical effects of blood sampling and handling in quantitative immunoassays for rheumatoid arthritis.

    PubMed

    Zhao, Xiaoyan; Qureshi, Ferhan; Eastman, P Scott; Manning, William C; Alexander, Claire; Robinson, William H; Hesterberg, Lyndal K

    2012-04-30

    Variability in pre-analytical blood sampling and handling can significantly impact results obtained in quantitative immunoassays. Understanding the impact of these variables is critical for accurate quantification and validation of biomarker measurements. Particularly, in the design and execution of large clinical trials, even small differences in sample processing and handling can have dramatic effects in analytical reliability, results interpretation, trial management and outcome. The effects of two common blood sampling methods (serum vs. plasma) and two widely-used serum handling methods (on the clot with ambient temperature shipping, "traditional", vs. centrifuged with cold chain shipping, "protocol") on protein and autoantibody concentrations were examined. Matched serum and plasma samples were collected from 32 rheumatoid arthritis (RA) patients representing a wide range of disease activity status. Additionally, a set of matched serum samples with two sample handling methods was collected. One tube was processed per manufacturer's instructions and shipped overnight on cold packs (protocol). The matched tube, without prior centrifugation, was simultaneously shipped overnight at ambient temperatures (traditional). Upon delivery, the traditional tube was centrifuged. All samples were subsequently aliquoted and frozen prior to analysis of protein and autoantibody biomarkers. Median correlation between paired serum and plasma across all autoantibody assays was 0.99 (0.98-1.00) with a median % difference of -3.3 (-7.5 to 6.0). In contrast, observed protein biomarker concentrations were significantly affected by sample types, with median correlation of 0.99 (0.33-1.00) and a median % difference of -10 (-55 to 23). When the two serum collection/handling methods were compared, the median correlation between paired samples for autoantibodies was 0.99 (0.91-1.00) with a median difference of 4%. In contrast, significant increases were observed in protein biomarker concentrations among certain biomarkers in samples processed with the 'traditional' method. Autoantibody quantification appears robust to both sample type (plasma vs. serum) and pre-analytical sample collection/handling methods (protocol vs. traditional). In contrast, for non-antibody protein biomarker concentrations, sample type had a significant impact; plasma samples generally exhibit decreased protein biomarker concentrations relative to serum. Similarly, sample handling significantly impacted the variability of protein biomarker concentrations. When biomarker concentrations are combined algorithmically into a single test score such as a multi-biomarker disease activity test for rheumatoid arthritis (MBDA), changes in protein biomarker concentrations may result in a bias of the score. These results illustrate the importance of characterizing pre-analytical methodology, sample type, sample processing and handling procedures for clinical testing in order to ensure test accuracy. Copyright © 2012 Elsevier B.V. All rights reserved.

  16. On Systems Thinking and Ways of Building It in Learning

    ERIC Educational Resources Information Center

    Abdyrova, Aitzhan; Galiyev, Temir; Yessekeshova, Maral; Aldabergenova, Saule; Alshynbayeva, Zhuldyz

    2016-01-01

    The article focuses on the issue of shaping learners' systems thinking skills in the context of traditional education using specially elaborated system methods that are implemented based on the standard textbook. Applying these methods naturally complements the existing learning process and contributes to an efficient development of learners'…

  17. Robust Methods for Sensing and Reconstructing Sparse Signals

    ERIC Educational Resources Information Center

    Carrillo, Rafael E.

    2012-01-01

    Compressed sensing (CS) is an emerging signal acquisition framework that goes against the traditional Nyquist sampling paradigm. CS demonstrates that a sparse, or compressible, signal can be acquired using a low rate acquisition process. Since noise is always present in practical data acquisition systems, sensing and reconstruction methods are…

  18. Rapid assessment of forest canopy and light regime using smartphone hemispherical photography.

    PubMed

    Bianchi, Simone; Cahalan, Christine; Hale, Sophie; Gibbons, James Michael

    2017-12-01

    Hemispherical photography (HP), implemented with cameras equipped with "fisheye" lenses, is a widely used method for describing forest canopies and light regimes. A promising technological advance is the availability of low-cost fisheye lenses for smartphone cameras. However, smartphone camera sensors cannot record a full hemisphere. We investigate whether smartphone HP is a cheaper and faster but still adequate operational alternative to traditional cameras for describing forest canopies and light regimes. We collected hemispherical pictures with both smartphone and traditional cameras in 223 forest sample points, across different overstory species and canopy densities. The smartphone image acquisition followed a faster and simpler protocol than that for the traditional camera. We automatically thresholded all images. We processed the traditional camera images for Canopy Openness (CO) and Site Factor estimation. For smartphone images, we took two pictures with different orientations per point and used two processing protocols: (i) we estimated and averaged total canopy gap from the two single pictures, and (ii) merging the two pictures together, we formed images closer to full hemispheres and estimated from them CO and Site Factors. We compared the same parameters obtained from different cameras and estimated generalized linear mixed models (GLMMs) between them. Total canopy gap estimated from the first processing protocol for smartphone pictures was on average significantly higher than CO estimated from traditional camera images, although with a consistent bias. Canopy Openness and Site Factors estimated from merged smartphone pictures of the second processing protocol were on average significantly higher than those from traditional cameras images, although with relatively little absolute differences and scatter. Smartphone HP is an acceptable alternative to HP using traditional cameras, providing similar results with a faster and cheaper methodology. Smartphone outputs can be directly used as they are for ecological studies, or converted with specific models for a better comparison to traditional cameras.

  19. An exploration of the knowledge, attitudes and beliefs of Xhosa men concerning traditional circumcision.

    PubMed

    Froneman, Salome; Kapp, Paul A

    2017-10-13

    The practice of traditional circumcision is associated with considerable morbidity and mortality, yet there is a paucity of literature that provides an understanding of the cultural values that influence men to choose traditional rather than medical circumcision.The aim of this study was to better understand the culture surrounding traditional circumcision, with a view to addressing morbidity and mortality rates associated with the Xhosa male initiation rituals.We explored Xhosa men's perceptions regarding the need for the risks and the social pressure to undergo traditional circumcision, the impact of non-initiation or failed initiation and the perceived barriers to obtaining medical help for the complications of traditional circumcisions. Individual in-depth interviews were conducted with 10 purposively sampled teenagers and adult men. The interviews were recorded, translated, transcribed and analysed using the framework method. Traditional circumcision was seen as essential to Xhosa culture. Participants rationalised many reasons for participating, including personal growth and development, family and peer pressure, independence and knowledge gained, a connection with ancestors and initiation into manhood. Despite publicity of the dangers of traditional circumcision and the hardships they have to endure, most young men still saw this process as necessary and worthwhile. Traditional initiation and circumcision are here to stay. The majority of boys still trust the elders and supernatural processes to guide them. However, some participants welcomed government initiatives to reduce human error causing unnecessary death and suffering. Current systems to prevent morbidity and mortality are insufficient and should be prioritised.

  20. Effect of wine processing and acute blood stasis on the serum pharmacochemistry of rhubarb: a possible explanation for processing mechanism.

    PubMed

    Wang, Min; Fu, Jinfeng; Lv, Mengying; Tian, Yuan; Xu, Fengguo; Song, Rui; Zhang, Zunjian

    2014-09-01

    As a specific item mentioned in traditional Chinese medicine theory, processing can fulfill different requirements of therapies. Crude and wine-processed rhubarbs are used as drastic and mild laxatives, respectively. In this study, a practical method based on ultra-fast liquid chromatography coupled with diode-array detection and ion trap time-of-flight mass spectrometry was developed to screen and analyze multiple absorbed bioactive components and metabolites in the serum of both normal and acute blood stasis rats after oral administration of crude or wine-processed rhubarbs. A total of 16 compounds, mainly including phase II metabolites, were tentatively identified. Possible explanations for the processing-induced changes in pharmacological effects of traditional Chinese medicines were first explored at serum pharmacochemistry level. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Sustainability Characterization for Additive Manufacturing

    PubMed Central

    Mani, Mahesh; Lyons, Kevin W; Gupta, SK

    2014-01-01

    Additive manufacturing (AM) has the potential to create geometrically complex parts that require a high degree of customization, using less material and producing less waste. Recent studies have shown that AM can be an economically viable option for use by the industry, yet there are some inherent challenges associated with AM for wider acceptance. The lack of standards in AM impedes its use for parts production since industries primarily depend on established standards in processes and material selection to ensure the consistency and quality. Inability to compare AM performance against traditional manufacturing methods can be a barrier for implementing AM processes. AM process sustainability has become a driver due to growing environmental concerns for manufacturing. This has reinforced the importance to understand and characterize AM processes for sustainability. Process characterization for sustainability will help close the gaps for comparing AM performance to traditional manufacturing methods. Based on a literature review, this paper first examines the potential environmental impacts of AM. A methodology for sustainability characterization of AM is then proposed to serve as a resource for the community to benchmark AM processes for sustainability. Next, research perspectives are discussed along with relevant standardization efforts. PMID:26601038

  2. Quantification of Protozoa and Viruses from Small Water Volumes

    PubMed Central

    Bonilla, J. Alfredo; Bonilla, Tonya D.; Abdelzaher, Amir M.; Scott, Troy M.; Lukasik, Jerzy; Solo-Gabriele, Helena M.; Palmer, Carol J.

    2015-01-01

    Large sample volumes are traditionally required for the analysis of waterborne pathogens. The need for large volumes greatly limits the number of samples that can be processed. The goals of this study were to compare extraction and detection procedures for quantifying protozoan parasites and viruses from small volumes of marine water. The intent was to evaluate a logistically simpler method of sample collection and processing that would facilitate direct pathogen measures as part of routine monitoring programs. Samples were collected simultaneously using a bilayer device with protozoa capture by size (top filter) and viruses capture by charge (bottom filter). Protozoan detection technologies utilized for recovery of Cryptosporidium spp. and Giardia spp. were qPCR and the more traditional immunomagnetic separation—IFA-microscopy, while virus (poliovirus) detection was based upon qPCR versus plaque assay. Filters were eluted using reagents consistent with the downstream detection technologies. Results showed higher mean recoveries using traditional detection methods over qPCR for Cryptosporidium (91% vs. 45%) and poliovirus (67% vs. 55%) whereas for Giardia the qPCR-based methods were characterized by higher mean recoveries (41% vs. 28%). Overall mean recoveries are considered high for all detection technologies. Results suggest that simultaneous filtration may be suitable for isolating different classes of pathogens from small marine water volumes. More research is needed to evaluate the suitability of this method for detecting pathogens at low ambient concentration levels. PMID:26114244

  3. Quantification of Protozoa and Viruses from Small Water Volumes.

    PubMed

    Bonilla, J Alfredo; Bonilla, Tonya D; Abdelzaher, Amir M; Scott, Troy M; Lukasik, Jerzy; Solo-Gabriele, Helena M; Palmer, Carol J

    2015-06-24

    Large sample volumes are traditionally required for the analysis of waterborne pathogens. The need for large volumes greatly limits the number of samples that can be processed. The aims of this study were to compare extraction and detection procedures for quantifying protozoan parasites and viruses from small volumes of marine water. The intent was to evaluate a logistically simpler method of sample collection and processing that would facilitate direct pathogen measures as part of routine monitoring programs. Samples were collected simultaneously using a bilayer device with protozoa capture by size (top filter) and viruses capture by charge (bottom filter). Protozoan detection technologies utilized for recovery of Cryptosporidium spp. and Giardia spp. were qPCR and the more traditional immunomagnetic separation-IFA-microscopy, while virus (poliovirus) detection was based upon qPCR versus plaque assay. Filters were eluted using reagents consistent with the downstream detection technologies. Results showed higher mean recoveries using traditional detection methods over qPCR for Cryptosporidium (91% vs. 45%) and poliovirus (67% vs. 55%) whereas for Giardia the qPCR-based methods were characterized by higher mean recoveries (41% vs. 28%). Overall mean recoveries are considered high for all detection technologies. Results suggest that simultaneous filtration may be suitable for isolating different classes of pathogens from small marine water volumes. More research is needed to evaluate the suitability of this method for detecting pathogens at low ambient concentration levels.

  4. A preliminary microbiological assessment of process hygiene of traditional outdoor camel slaughter in Sahrawi refugee camps.

    PubMed

    Corrò, M; Saleh-Mohamed-Lamin, S; Jatri-Hamdi, S; Slut-Ahmed, B; Mohamed-Lejlifa, S; Di Lello, S; Rossi, D; Broglia, A; Vivas-Alegre, L

    2012-10-01

    The aim of this study was to investigate the hygiene performance of a camel (Camelus dromedarius) slaughtering process as carried out with the traditional method in the Sahrawi refugee camps located in southwestern Algeria. The camel slaughtering process in this region differs significantly from that carried out in commercial abattoirs. Slaughtering is performed outdoors in desert areas, and dehiding of the carcass is approached via the dorsoventral route rather than the classic ventrodorsal route. Samples were taken from 10 camel carcasses from three different areas: the hide, the carcass meat immediately after dehiding, and the meat after final cutting. Enterobacteriaceae counts (EC) were enumerated employing conventional laboratory techniques. Carcass meat samples resulted in EC below the detection limit more frequently if the hide samples from the same carcass had also EC counts below the detection limit. Because of the low number of trials, the calculation of statistical significance of the results was not possible. Further experimental research is needed in order to validate the results presented in this study. The comparison of the microbiological hygiene performance between dorsal dehiding and traditional ventral dehiding of slaughtered animals could serve to validate the hypothesis of the potential positive impact of the dorsal dehiding method in carcass meat hygiene.

  5. A Bayesian Approach to Determination of F, D, and Z Values Used in Steam Sterilization Validation.

    PubMed

    Faya, Paul; Stamey, James D; Seaman, John W

    2017-01-01

    For manufacturers of sterile drug products, steam sterilization is a common method used to provide assurance of the sterility of manufacturing equipment and products. The validation of sterilization processes is a regulatory requirement and relies upon the estimation of key resistance parameters of microorganisms. Traditional methods have relied upon point estimates for the resistance parameters. In this paper, we propose a Bayesian method for estimation of the well-known D T , z , and F o values that are used in the development and validation of sterilization processes. A Bayesian approach allows the uncertainty about these values to be modeled using probability distributions, thereby providing a fully risk-based approach to measures of sterility assurance. An example is given using the survivor curve and fraction negative methods for estimation of resistance parameters, and we present a means by which a probabilistic conclusion can be made regarding the ability of a process to achieve a specified sterility criterion. LAY ABSTRACT: For manufacturers of sterile drug products, steam sterilization is a common method used to provide assurance of the sterility of manufacturing equipment and products. The validation of sterilization processes is a regulatory requirement and relies upon the estimation of key resistance parameters of microorganisms. Traditional methods have relied upon point estimates for the resistance parameters. In this paper, we propose a Bayesian method for estimation of the critical process parameters that are evaluated in the development and validation of sterilization processes. A Bayesian approach allows the uncertainty about these parameters to be modeled using probability distributions, thereby providing a fully risk-based approach to measures of sterility assurance. An example is given using the survivor curve and fraction negative methods for estimation of resistance parameters, and we present a means by which a probabilistic conclusion can be made regarding the ability of a process to achieve a specified sterility criterion. © PDA, Inc. 2017.

  6. Rapid and low-cost prototyping of medical devices using 3D printed molds for liquid injection molding.

    PubMed

    Chung, Philip; Heller, J Alex; Etemadi, Mozziyar; Ottoson, Paige E; Liu, Jonathan A; Rand, Larry; Roy, Shuvo

    2014-06-27

    Biologically inert elastomers such as silicone are favorable materials for medical device fabrication, but forming and curing these elastomers using traditional liquid injection molding processes can be an expensive process due to tooling and equipment costs. As a result, it has traditionally been impractical to use liquid injection molding for low-cost, rapid prototyping applications. We have devised a method for rapid and low-cost production of liquid elastomer injection molded devices that utilizes fused deposition modeling 3D printers for mold design and a modified desiccator as an injection system. Low costs and rapid turnaround time in this technique lower the barrier to iteratively designing and prototyping complex elastomer devices. Furthermore, CAD models developed in this process can be later adapted for metal mold tooling design, enabling an easy transition to a traditional injection molding process. We have used this technique to manufacture intravaginal probes involving complex geometries, as well as overmolding over metal parts, using tools commonly available within an academic research laboratory. However, this technique can be easily adapted to create liquid injection molded devices for many other applications.

  7. Modified glass fibre reinforced polymer composites

    NASA Astrophysics Data System (ADS)

    Cao, Yumei

    A high ratio of strength to density and relatively low-cost are some of the significant features of glass fibre reinforced polymer composites (GFRPCs) that made them one of the most rapidly developed materials in recent years. They are widely used as the material of construction in the areas of aerospace, marine and everyday life, such as airplane, helicopter, boat, canoe, fishing rod, racket, etc. Traditionally, researchers tried to raise the mechanical properties and keep a high strength/weight ratio using all or some of the following methods: increasing the volume fraction of the fibre; using different polymeric matrix material; or changing the curing conditions. In recent years, some new techniques and processing methods were developed to further improve the mechanical properties of glass fibre (GF) reinforced polymer composite. For example, by modifying the surface condition of the GF, both the interface strength between the GF and the polymer matrix and the shear strength of the final composite can be significantly increased. Also, by prestressing the fibre during the curing process of the composite, the tensile, flexural and the impact properties of the composite can be greatly improved. In this research project, a new method of preparing GFRPCs, which combined several traditional and modern techniques together, was developed. This new method includes modification of the surface of the GF with silica particles, application of different levels of prestressing on the GF during the curing process, and the change of the fibre volume fraction and curing conditions in different sets of experiments. The results of the new processing were tested by the three-point bend test, the short beam shear test and the impact test to determine the new set of properties so formed in the composite material. Scanning electronic microscopy (SEM) was used to study the fracture surface of the new materials after the mechanical tests were performed. By taking advantages of the traditional and modern techniques at the same time, the newly developed modified glass fibre reinforced epoxy matrix composites (MGFRECs) have much improved comprehensive properties. The flexural strength, the flexural modulus, the shear modulus and the impact energy (Izod impact test) of the composites were improved up to 87%, 74%, 30% and 89% respectively when modified samples were compared to the samples made by the traditional methods.

  8. [Survey scheme of the main Chinese medicines resources].

    PubMed

    Chen, Shi-lin; Zhang, Ben-gang; Yang, Zhi; Su, Gang-qiang; Zhao, Run-huai; Huang, Lin-fang; Ma, Xiao-jun; Zhang, Jin-sheng; Xiao, Pei-gen

    2005-08-01

    The survey of Chinese medicines resources concerns the development of the traditional Chinese medicine industry. It also directly influences the modernization process of traditional Chinese medicines. Owing to lacking of the scientific data on the Chinese medicines resources, it is a extremely urgent work to carry out survey of main Chinese medicine resources in nationwide. This paper explains the meaning and necessity. And it also investigated the survey object, contents, new technologies and methods.

  9. Deep Learning and Image Processing for Automated Crack Detection and Defect Measurement in Underground Structures

    NASA Astrophysics Data System (ADS)

    Panella, F.; Boehm, J.; Loo, Y.; Kaushik, A.; Gonzalez, D.

    2018-05-01

    This work presents the combination of Deep-Learning (DL) and image processing to produce an automated cracks recognition and defect measurement tool for civil structures. The authors focus on tunnel civil structures and survey and have developed an end to end tool for asset management of underground structures. In order to maintain the serviceability of tunnels, regular inspection is needed to assess their structural status. The traditional method of carrying out the survey is the visual inspection: simple, but slow and relatively expensive and the quality of the output depends on the ability and experience of the engineer as well as on the total workload (stress and tiredness may influence the ability to observe and record information). As a result of these issues, in the last decade there is the desire to automate the monitoring using new methods of inspection. The present paper has the goal of combining DL with traditional image processing to create a tool able to detect, locate and measure the structural defect.

  10. Adjacent slice prostate cancer prediction to inform MALDI imaging biomarker analysis

    NASA Astrophysics Data System (ADS)

    Chuang, Shao-Hui; Sun, Xiaoyan; Cazares, Lisa; Nyalwidhe, Julius; Troyer, Dean; Semmes, O. John; Li, Jiang; McKenzie, Frederic D.

    2010-03-01

    Prostate cancer is the second most common type of cancer among men in US [1]. Traditionally, prostate cancer diagnosis is made by the analysis of prostate-specific antigen (PSA) levels and histopathological images of biopsy samples under microscopes. Proteomic biomarkers can improve upon these methods. MALDI molecular spectra imaging is used to visualize protein/peptide concentrations across biopsy samples to search for biomarker candidates. Unfortunately, traditional processing methods require histopathological examination on one slice of a biopsy sample while the adjacent slice is subjected to the tissue destroying desorption and ionization processes of MALDI. The highest confidence tumor regions gained from the histopathological analysis are then mapped to the MALDI spectra data to estimate the regions for biomarker identification from the MALDI imaging. This paper describes a process to provide a significantly better estimate of the cancer tumor to be mapped onto the MALDI imaging spectra coordinates using the high confidence region to predict the true area of the tumor on the adjacent MALDI imaged slice.

  11. Rethinking the architectural design concept in the digital culture (in architecture's practice perspective)

    NASA Astrophysics Data System (ADS)

    Prawata, Albertus Galih

    2017-11-01

    The architectural design stages in architectural practices or in architectural design studio consist of many aspects. One of them is during the early phases of the design process, where the architects or designers try to interpret the project brief into the design concept. This paper is a report of the procedure of digital tools in the early design process in an architectural practice in Jakarta. It targets principally the use of BIM and digital modeling to generate information and transform them into conceptual forms, which is not very common in Indonesian architectural practices. Traditionally, the project brief is transformed into conceptual forms by using sketches, drawings, and physical model. The new method using digital tools shows that it is possible to do the same thing during the initial stage of the design process to create early architectural design forms. Architect's traditional tools and methods begin to be replaced effectively by digital tools, which would drive bigger opportunities for innovation.

  12. What Makes School Ethnography "Ethnographic?"

    ERIC Educational Resources Information Center

    Erickson, Frederick

    Ethnography as an inquiry process guided by a point of view rather than as a reporting process guided by a standard technique or set of techniques is the main point of this essay which suggests the application of Malinowski's theories and methods to an ethnology of the school, indicates reasons why traditional ethnography is inadequate to the…

  13. Explosively generated shock wave processing of metal powders by instrumented detonics

    NASA Astrophysics Data System (ADS)

    Sharma, A. D.; Sharma, A. K.; Thakur, N.

    2013-06-01

    The highest pressures generated by dynamic processes resulting either from high velocity impact or by spontaneous release of high energy rate substances in direct contact with a metal find superior applications over normal mechanical means. The special feature of explosive loading to the powder materials over traditional methods is its controlled detonation pressure which directly transmits shock energy to the materials which remain entrapped inside powder resulting into several micro-structural changes and hence improved mechanical properties. superalloy powders have been compacted nearer to the theoretical density by shock wave consolidation. In a single experimental set-up, compaction of metal powder and measurement of detonation velocity have been achieved successfully by using instrumented detonics. The thrust on the work is to obtain uniform, crack-free and fracture-less compacts of superalloys having intact crystalline structure as has been examined from FE-SEM, XRD and mechanical studies. Shock wave processing is an emerging technique and receiving much attention of the materials scientists and engineers owing to its excellent advantages over traditional metallurgical methods due to short processing time, scaleup advantage and controlled detonation pressure.

  14. Assessing the economics of processing end-of-life vehicles through manual dismantling.

    PubMed

    Tian, Jin; Chen, Ming

    2016-10-01

    Most dismantling enterprises in a number of developing countries, such as China, usually adopt the "manual+mechanical" dismantling approach to process end-of-life vehicles. However, the automobile industry does not have a clear indicator to reasonably and effectively determine the manual dismantling degree for end-of-life vehicles. In this study, five different dismantling scenarios and an economic system for end-of-life vehicles were developed based on the actual situation of end-of-life vehicles. The fuzzy analytic hierarchy process was applied to set the weights of direct costs, indirect costs, and sales and to obtain an optimal manual dismantling scenario. Results showed that although the traditional method of "dismantling to the end" can guarantee the highest recycling rate, this method is not the best among all the scenarios. The profit gained in the optimal scenario is 100.6% higher than that in the traditional scenario. The optimal manual dismantling scenario showed that enterprises are required to select suitable parts to process through manual dismantling. Selecting suitable parts maximizes economic profit and improves dismantling speed. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Effect of processing methods on the nutritional content of three traditional vegetables leaves: Amaranth, black nightshade and jute mallow.

    PubMed

    Traoré, Korotimi; Parkouda, Charles; Savadogo, Aly; Ba/Hama, Fatoumata; Kamga, Regine; Traoré, Yves

    2017-11-01

    The study assessed changes in nutritional content of some commonly consumed traditional vegetables subjected to postharvest processes. Amaranth ( Amaranthus cruentus L.), black nightshade ( Solanum scabrum Mill.) and jute mallow ( Corchorus olitorius L.) leaves used as vegetables were subjected to blanching, boiling and drying. The proximate composition and β-carotene content of fresh and processed leaves were determined. Amaranth, black nightshade and jute mallow leaves had 25.21%, 39.74% and 29.18% of protein, respectively. The β-carotene levels were 16.40, 25.25 and 27.74 mg/100 g for black nightshade amaranth and jute mallow leaves, respectively. The ash content was 10.57% for black nightshade, 12.40% for jute mallow and 16.33% for amaranth. Processing methods caused decreases of β-carotene and crude lipid content. Boiling for 30 min or more resulted in large loss of β-carotene. Drying under shade resulted in less loss of β-carotene than drying in cabinet at 50 and 60°C.

  16. Fast cat-eye effect target recognition based on saliency extraction

    NASA Astrophysics Data System (ADS)

    Li, Li; Ren, Jianlin; Wang, Xingbin

    2015-09-01

    Background complexity is a main reason that results in false detection in cat-eye target recognition. Human vision has selective attention property which can help search the salient target from complex unknown scenes quickly and precisely. In the paper, we propose a novel cat-eye effect target recognition method named Multi-channel Saliency Processing before Fusion (MSPF). This method combines traditional cat-eye target recognition with the selective characters of visual attention. Furthermore, parallel processing enables it to achieve fast recognition. Experimental results show that the proposed method performs better in accuracy, robustness and speed compared to other methods.

  17. Introduction of an all-electronic administrative process for a major international pediatric surgical meeting.

    PubMed

    Applebaum, Harry; Boles, Kay; Atkinson, James B

    2003-12-01

    The administrative process for annual meetings is time consuming and increasingly costly when accomplished by traditional postal, fax, and telephone methods. The Pacific Association of Pediatric Surgeons introduced an all-electronic communication format for its 2002 annual meeting. Attendee acceptance and administrative and financial impact were evaluated. Interested physicians were directed to a Website containing detailed information and electronic forms. E-mail was used for the abstract selection and manuscript submission processes. Attendees were surveyed to evaluate the new format. Administrative costs for the new format were compared with estimated costs for a comparable traditionally managed meeting. Attendance was similar to that at previous US meetings. Eighty-two percent of respondents approved of the all-electronic format, although 48% believed a choice should remain. None suggested a complete return to the traditional format. Abstract and manuscript processing time was reduced substantially as were administrative costs (79.43 dollars savings per physician registrant). Adoption of an all-electronic annual meeting administrative process was associated with substantial cost reduction, increased efficiency, and excellent attendee satisfaction. This technology can help avoid increased registration fees while easing the burden on physician volunteers.

  18. On the possibility of producing true real-time retinal cross-sectional images using a graphics processing unit enhanced master-slave optical coherence tomography system.

    PubMed

    Bradu, Adrian; Kapinchev, Konstantin; Barnes, Frederick; Podoleanu, Adrian

    2015-07-01

    In a previous report, we demonstrated master-slave optical coherence tomography (MS-OCT), an OCT method that does not need resampling of data and can be used to deliver en face images from several depths simultaneously. In a separate report, we have also demonstrated MS-OCT's capability of producing cross-sectional images of a quality similar to those provided by the traditional Fourier domain (FD) OCT technique, but at a much slower rate. Here, we demonstrate that by taking advantage of the parallel processing capabilities offered by the MS-OCT method, cross-sectional OCT images of the human retina can be produced in real time. We analyze the conditions that ensure a true real-time B-scan imaging operation and demonstrate in vivo real-time images from human fovea and the optic nerve, with resolution and sensitivity comparable to those produced using the traditional FD-based method, however, without the need of data resampling.

  19. Detecting subtle hydrochemical anomalies with multivariate statistics: an example from homogeneous groundwaters in the Great Artesian Basin, Australia

    NASA Astrophysics Data System (ADS)

    O'Shea, Bethany; Jankowski, Jerzy

    2006-12-01

    The major ion composition of Great Artesian Basin groundwater in the lower Namoi River valley is relatively homogeneous in chemical composition. Traditional graphical techniques have been combined with multivariate statistical methods to determine whether subtle differences in the chemical composition of these waters can be delineated. Hierarchical cluster analysis and principal components analysis were successful in delineating minor variations within the groundwaters of the study area that were not visually identified in the graphical techniques applied. Hydrochemical interpretation allowed geochemical processes to be identified in each statistically defined water type and illustrated how these groundwaters differ from one another. Three main geochemical processes were identified in the groundwaters: ion exchange, precipitation, and mixing between waters from different sources. Both statistical methods delineated an anomalous sample suspected of being influenced by magmatic CO2 input. The use of statistical methods to complement traditional graphical techniques for waters appearing homogeneous is emphasized for all investigations of this type. Copyright

  20. Salting by Vacuum Brine Impregnation in Nitrite-Free Lonza: Effect on Enterobacteriaceae.

    PubMed

    Serio, Annalisa; Chaves-López, Clemencia; Rossi, Chiara; Pittia, Paola; Rosa, Marco Dalla; Paparella, Antonello

    2017-01-24

    Lonza is a traditional Italian meat product made from whole pork muscles, which is typically cured by dry salting. In this work, we study the effects of vacuum brine impregnation (VBI) as an alternative salting method on the survival of Enterobacteriaceae, in presence and in absence of nitrites. In comparison with the traditional brining process, VBI contributed to reducing the Enterobacteriaceae population on product surface but induced contamination of the inner muscle tissues. Our results suggest that the species isolated became adapted to processing conditions, and salt tolerance was species- or strain-dependent. This result is of particular importance for future applications of VBI in lonza manufacturing.

  1. The research on the mean shift algorithm for target tracking

    NASA Astrophysics Data System (ADS)

    CAO, Honghong

    2017-06-01

    The traditional mean shift algorithm for target tracking is effective and high real-time, but there still are some shortcomings. The traditional mean shift algorithm is easy to fall into local optimum in the tracking process, the effectiveness of the method is weak when the object is moving fast. And the size of the tracking window never changes, the method will fail when the size of the moving object changes, as a result, we come up with a new method. We use particle swarm optimization algorithm to optimize the mean shift algorithm for target tracking, Meanwhile, SIFT (scale-invariant feature transform) and affine transformation make the size of tracking window adaptive. At last, we evaluate the method by comparing experiments. Experimental result indicates that the proposed method can effectively track the object and the size of the tracking window changes.

  2. Hospital positioning: a strategic tool for the 1990s.

    PubMed

    San Augustine, A J; Long, W J; Pantzallis, J

    1992-03-01

    The authors extend the process of market positioning in the health care sector by focusing on the simultaneous utilization of traditional research methods and emerging new computer-based adaptive perceptual mapping technologies and techniques.

  3. Comparing Thermal Process Validation Methods for Salmonella Inactivation on Almond Kernels.

    PubMed

    Jeong, Sanghyup; Marks, Bradley P; James, Michael K

    2017-01-01

    Ongoing regulatory changes are increasing the need for reliable process validation methods for pathogen reduction processes involving low-moisture products; however, the reliability of various validation methods has not been evaluated. Therefore, the objective was to quantify accuracy and repeatability of four validation methods (two biologically based and two based on time-temperature models) for thermal pasteurization of almonds. Almond kernels were inoculated with Salmonella Enteritidis phage type 30 or Enterococcus faecium (NRRL B-2354) at ~10 8 CFU/g, equilibrated to 0.24, 0.45, 0.58, or 0.78 water activity (a w ), and then heated in a pilot-scale, moist-air impingement oven (dry bulb 121, 149, or 177°C; dew point <33.0, 69.4, 81.6, or 90.6°C; v air = 2.7 m/s) to a target lethality of ~4 log. Almond surface temperatures were measured in two ways, and those temperatures were used to calculate Salmonella inactivation using a traditional (D, z) model and a modified model accounting for process humidity. Among the process validation methods, both methods based on time-temperature models had better repeatability, with replication errors approximately half those of the surrogate ( E. faecium ). Additionally, the modified model yielded the lowest root mean squared error in predicting Salmonella inactivation (1.1 to 1.5 log CFU/g); in contrast, E. faecium yielded a root mean squared error of 1.2 to 1.6 log CFU/g, and the traditional model yielded an unacceptably high error (3.4 to 4.4 log CFU/g). Importantly, the surrogate and modified model both yielded lethality predictions that were statistically equivalent (α = 0.05) to actual Salmonella lethality. The results demonstrate the importance of methodology, a w , and process humidity when validating thermal pasteurization processes for low-moisture foods, which should help processors select and interpret validation methods to ensure product safety.

  4. Teaching to Think: Applying the Socratic Method outside the Law School Setting

    ERIC Educational Resources Information Center

    Peterson, Evan

    2009-01-01

    An active learning process has the potential to provide educational benefits above-and-beyond what they might receive from more traditional, passive approaches. The Socratic Method is a unique approach to passive learning that facilitates critical thinking, open-mindedness, and teamwork. By imposing a series of guided questions to students, an…

  5. A method of fast mosaic for massive UAV images

    NASA Astrophysics Data System (ADS)

    Xiang, Ren; Sun, Min; Jiang, Cheng; Liu, Lei; Zheng, Hui; Li, Xiaodong

    2014-11-01

    With the development of UAV technology, UAVs are used widely in multiple fields such as agriculture, forest protection, mineral exploration, natural disaster management and surveillances of public security events. In contrast of traditional manned aerial remote sensing platforms, UAVs are cheaper and more flexible to use. So users can obtain massive image data with UAVs, but this requires a lot of time to process the image data, for example, Pix4UAV need approximately 10 hours to process 1000 images in a high performance PC. But disaster management and many other fields require quick respond which is hard to realize with massive image data. Aiming at improving the disadvantage of high time consumption and manual interaction, in this article a solution of fast UAV image stitching is raised. GPS and POS data are used to pre-process the original images from UAV, belts and relation between belts and images are recognized automatically by the program, in the same time useless images are picked out. This can boost the progress of finding match points between images. Levenberg-Marquard algorithm is improved so that parallel computing can be applied to shorten the time of global optimization notably. Besides traditional mosaic result, it can also generate superoverlay result for Google Earth, which can provide a fast and easy way to show the result data. In order to verify the feasibility of this method, a fast mosaic system of massive UAV images is developed, which is fully automated and no manual interaction is needed after original images and GPS data are provided. A test using 800 images of Kelan River in Xinjiang Province shows that this system can reduce 35%-50% time consumption in contrast of traditional methods, and increases respond speed of UAV image processing rapidly.

  6. An improved correlation method for determining the period of a torsion pendulum

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Luo Jie; Wang Dianhong

    Considering variation of environment temperature and unhomogeneity of background gravitational field, an improved correlation method was proposed to determine the variational period of a torsion pendulum with high precision. The result of processing experimental data shows that the uncertainty of determining the period with this method has been improved about twofolds than traditional correlation method, which is significant for the determination of gravitational constant with time-of-swing method.

  7. Transient simulation of hydropower station with consideration of three-dimensional unsteady flow in turbine

    NASA Astrophysics Data System (ADS)

    Huang, W. D.; Fan, H. G.; Chen, N. X.

    2012-11-01

    To study the interaction between the transient flow in pipe and the unsteady turbulent flow in turbine, a coupled model of the transient flow in the pipe and three-dimensional unsteady flow in the turbine is developed based on the method of characteristics and the fluid governing equation in the accelerated rotational relative coordinate. The load-rejection process under the closing of guide vanes of the hydraulic power plant is simulated by the coupled method, the traditional transient simulation method and traditional three-dimensional unsteady flow calculation method respectively and the results are compared. The pressure, unit flux and rotation speed calculated by three methods show a similar change trend. However, because the elastic water hammer in the pipe and the pressure fluctuation in the turbine have been considered in the coupled method, the increase of pressure at spiral inlet is higher and the pressure fluctuation in turbine is stronger.

  8. A Portable Dynamic Laser Speckle System for Sensing Long-Term Changes Caused by Treatments in Painting Conservation.

    PubMed

    Pérez, Alberto J; González-Peña, Rolando J; Braga, Roberto; Perles, Ángel; Pérez-Marín, Eva; García-Diego, Fernando J

    2018-01-11

    Dynamic laser speckle (DLS) is used as a reliable sensor of activity for all types of materials. Traditional applications are based on high-rate captures (usually greater than 10 frames-per-second, fps). Even for drying processes in conservation treatments, where there is a high level of activity in the first moments after the application and slower activity after some minutes or hours, the process is based on the acquisition of images at a time rate that is the same in moments of high and low activity. In this work, we present an alternative approach to track the drying process of protective layers and other painting conservation processes that take a long time to reduce their levels of activity. We illuminate, using three different wavelength lasers, a temporary protector (cyclododecane) and a varnish, and monitor them using a low fps rate during long-term drying. The results are compared to the traditional method. This work also presents a monitoring method that uses portable equipment. The results present the feasibility of using the portable device and show the improved sensitivity of the dynamic laser speckle when sensing the long-term process for drying cyclododecane and varnish in conservation.

  9. Performance of Traditional and Molecular Methods for Detecting Biological Agents in Drinking Water

    USGS Publications Warehouse

    Francy, Donna S.; Bushon, Rebecca N.; Brady, Amie M.G.; Bertke, Erin E.; Kephart, Christopher M.; Likirdopulos, Christina A.; Mailot, Brian E.; Schaefer, Frank W.; Lindquist, H.D. Alan

    2009-01-01

    To reduce the impact from a possible bioterrorist attack on drinking-water supplies, analytical methods are needed to rapidly detect the presence of biological agents in water. To this end, 13 drinking-water samples were collected at 9 water-treatment plants in Ohio to assess the performance of a molecular method in comparison to traditional analytical methods that take longer to perform. Two 100-liter samples were collected at each site during each sampling event; one was seeded in the laboratory with six biological agents - Bacillus anthracis (B. anthracis), Burkholderia cepacia (as a surrogate for Bu. pseudomallei), Francisella tularensis (F. tularensis), Salmonella Typhi (S. Typhi), Vibrio cholerae (V. cholerae), and Cryptospordium parvum (C. parvum). The seeded and unseeded samples were processed by ultrafiltration and analyzed by use of quantiative polymerase chain reaction (qPCR), a molecular method, and culture methods for bacterial agents or the immunomagnetic separation/fluorescent antibody (IMS/FA) method for C. parvum as traditional methods. Six replicate seeded samples were also processed and analyzed. For traditional methods, recoveries were highly variable between samples and even between some replicate samples, ranging from below detection to greater than 100 percent. Recoveries were significantly related to water pH, specific conductance, and dissolved organic carbon (DOC) for all bacteria combined by culture methods, but none of the water-quality characteristics tested were related to recoveries of C. parvum by IMS/FA. Recoveries were not determined by qPCR because of problems in quantifying organisms by qPCR in the composite seed. Instead, qPCR results were reported as detected, not detected (no qPCR signal), or +/- detected (Cycle Threshold or 'Ct' values were greater than 40). Several sample results by qPCR were omitted from the dataset because of possible problems with qPCR reagents, primers, and probes. For the remaining 14 qPCR results (including some replicate samples), F. tularensis and V. cholerae were detected in all samples after ultrafiltration, B. anthracis was detected in 13 and +/- detected in 1 sample, and C. parvum was detected in 9 and +/- detected in 4 samples. Bu. cepacia was detected in nine samples, +/- detected in two samples, and not detected in three samples (for two out of three samples not detected, a different strain was used). The qPCR assay for V. cholerae provided two false positive - but late - signals in one unseeded sample. Numbers found by qPCR after ultrafiltration were significantly or nearly significantly related to those found by traditional methods for B. anthracis, F. tularensis, and V. cholerae but not for Bu. cepacia and C. parvum. A qPCR assay for S. Typhi was not available. The qPCR method can be used to rapidly detect B. anthracis, F. tularensis, and V. cholerae with some certainty in drinking-water samples, but additional work would be needed to optimize and test qPCR for Bu. cepacia and C. parvum and establish relations to traditional methods. The specificity for the V. cholerae assay needs to be further investigated. Evidence is provided that ultrafiltration and qPCR are promising methods to rapidly detect biological agents in the Nation's drinking-water supplies and thus reduce the impact and consequences from intentional bioterrorist events. To our knowledge, this is the first study to compare the use of traditional and qPCR methods to detect biological agents in large-volume drinking-water samples.

  10. Acoustics based assessment of respiratory diseases using GMM classification.

    PubMed

    Mayorga, P; Druzgalski, C; Morelos, R L; Gonzalez, O H; Vidales, J

    2010-01-01

    The focus of this paper is to present a method utilizing lung sounds for a quantitative assessment of patient health as it relates to respiratory disorders. In order to accomplish this, applicable traditional techniques within the speech processing domain were utilized to evaluate lung sounds obtained with a digital stethoscope. Traditional methods utilized in the evaluation of asthma involve auscultation and spirometry, but utilization of more sensitive electronic stethoscopes, which are currently available, and application of quantitative signal analysis methods offer opportunities of improved diagnosis. In particular we propose an acoustic evaluation methodology based on the Gaussian Mixed Models (GMM) which should assist in broader analysis, identification, and diagnosis of asthma based on the frequency domain analysis of wheezing and crackles.

  11. Improving traditional balancing methods for high-speed rotors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ling, J.; Cao, Y.

    1996-01-01

    This paper introduces frequency response functions, analyzes the relationships between the frequency response functions and influence coefficients theoretically, and derives corresponding mathematical equations for high-speed rotor balancing. The relationships between the imbalance masses on the rotor and frequency response functions are also analyzed based upon the modal balancing method, and the equations related to the static and dynamic imbalance masses and the frequency response function are obtained. Experiments on a high-speed rotor balancing rig were performed to verify the theory, and the experimental data agree satisfactorily with the analytical solutions. The improvement on the traditional balancing method proposed in thismore » paper will substantially reduce the number of rotor startups required during the balancing process of rotating machinery.« less

  12. Interdiffusion of Polycarbonate in Fused Deposition Modeling Welds

    NASA Astrophysics Data System (ADS)

    Seppala, Jonathan; Forster, Aaron; Satija, Sushil; Jones, Ronald; Migler, Kalman

    2015-03-01

    Fused deposition modeling (FDM), a now common and inexpensive additive manufacturing method, produces 3D objects by extruding molten polymer layer-by-layer. Compared to traditional polymer processing methods (injection, vacuum, and blow molding), FDM parts have inferior mechanical properties, surface finish, and dimensional stability. From a polymer processing point of view the polymer-polymer weld between each layer limits the mechanical strength of the final part. Unlike traditional processing methods, where the polymer is uniformly melted and entangled, FDM welds are typically weaker due to the short time available for polymer interdiffusion and entanglement. To emulate the FDM process thin film bilayers of polycarbonate/d-polycarbonate were annealed using scaled times and temperatures accessible in FDM. Shift factors from Time-Temperature Superposition, measured by small amplitude oscillatory shear, were used to calculate reasonable annealing times (min) at temperatures below the actual extrusion temperature. The extent of interdiffusion was then measured using neutron reflectivity. Analogous specimens were prepared to characterize the mechanical properties. FDM build parameters were then related to interdiffusion between welded layers and mechanical properties. Understating the relationship between build parameters, interdiffusion, and mechanical strength will allow FDM users to print stronger parts in an intelligent manner rather than using trial-and-error and build parameter lock-in.

  13. The characterization of lactic acid bacteria isolated during the traditional production of Užička sausage

    NASA Astrophysics Data System (ADS)

    Borović, B.; Velebit, B.; Vesković, S.; Lakićević, B.; Baltić, T.

    2017-09-01

    Užička sausage is a traditionally fermented dry sausage that is produced in western Serbia. It is made of beef and pork with the addition of solid fat and natural spices. The whole manufacturing process lasted for 21 days. The goal of this study was to create a collection of lactic acid bacteria isolated during the ripening and identify them using molecular methods. A total of 50 isolates from different stages of ripening (fermentation and drying) were identified by molecular methods. Leuconococcus mesenteroides, Lactobacillus brevis, and Lactobacillus sakei were the predominant microorganisms in Užička sausage.

  14. Sensory and Quality Evaluation of Traditional Compared with Power Ultrasound Processed Corn (Zea Mays) Tortilla Chips.

    PubMed

    Janve, Bhaskar; Yang, Wade; Sims, Charles

    2015-06-01

    Power ultrasound reduces the traditional corn steeping time from 18 to 1.5 h during tortilla chips dough (masa) processing. This study sought to examine consumer (n = 99) acceptability and quality of tortilla chips made from the masa by traditional compared with ultrasonic methods. Overall appearance, flavor, and texture acceptability scores were evaluated using a 9-point hedonic scale. The baked chips (process intermediate) before and after frying (finished product) were analyzed using a texture analyzer and machine vision. The texture values were determined using the 3-point bend test using breaking force gradient (BFG), peak breaking force (PBF), and breaking distance (BD). The fracturing properties determined by the crisp fracture support rig using fracture force gradient (FFG), peak fracture force (PFF), and fracture distance (FD). The machine vision evaluated the total surface area, lightness (L), color difference (ΔE), Hue (°h), and Chroma (C*). The results were evaluated by analysis of variance and means were separated using Tukey's test. Machine vision values of L, °h, were higher (P < 0.05) and ΔE was lower (P < 0.05) for fried and L, °h were significantly (P < 0.05) higher for baked chips produced from ultra-sonication as compare to traditional. Baked chips texture for ultra-sonication was significantly higher (P < 0.05) on BFG, BPD, PFF, and FD. Fried tortilla chips texture were higher significantly (P < 0.05) in BFG and PFF for ultra-sonication than traditional processing. However, the instrumental differences were not detected in sensory analysis, concluding possibility of power ultrasound as potential tortilla chips processing aid. © 2015 Institute of Food Technologists®

  15. A Principled Approach to the Specification of System Architectures for Space Missions

    NASA Technical Reports Server (NTRS)

    McKelvin, Mark L. Jr.; Castillo, Robert; Bonanne, Kevin; Bonnici, Michael; Cox, Brian; Gibson, Corrina; Leon, Juan P.; Gomez-Mustafa, Jose; Jimenez, Alejandro; Madni, Azad

    2015-01-01

    Modern space systems are increasing in complexity and scale at an unprecedented pace. Consequently, innovative methods, processes, and tools are needed to cope with the increasing complexity of architecting these systems. A key systems challenge in practice is the ability to scale processes, methods, and tools used to architect complex space systems. Traditionally, the process for specifying space system architectures has largely relied on capturing the system architecture in informal descriptions that are often embedded within loosely coupled design documents and domain expertise. Such informal descriptions often lead to misunderstandings between design teams, ambiguous specifications, difficulty in maintaining consistency as the architecture evolves throughout the system development life cycle, and costly design iterations. Therefore, traditional methods are becoming increasingly inefficient to cope with ever-increasing system complexity. We apply the principles of component-based design and platform-based design to the development of the system architecture for a practical space system to demonstrate feasibility of our approach using SysML. Our results show that we are able to apply a systematic design method to manage system complexity, thus enabling effective data management, semantic coherence and traceability across different levels of abstraction in the design chain. Just as important, our approach enables interoperability among heterogeneous tools in a concurrent engineering model based design environment.

  16. The Dosage Form of Aragh in Treatment, from the Iranian Traditional Medicine Perspective

    PubMed Central

    Adl, Mehdi; Emtiazi, Majid

    2016-01-01

    Background: The Iranian traditional medicine is one of the branches of complementary medicine and it is based on using the dosage forms of plants. One of the most common forms of pharmaceutical plants is Aragh. Due to ease-of-use, distillate is a more acceptable form among the public. In this article, it is attempted to study the usage forms and effects of Aragh according to the valid traditional medicine resources. Methods: This article is a review of Iranian traditional medicine textbooks such as Makhzan-ul-dawiah, Gharabadin Kabir, Cannon of Medicine, and other recent texts on medical plants. Results: According to the traditional medicine, the process of getting Aragh is a kind of distillation, which is performed by using Ghar and Alembic (the equipment that are used in distillation). Distillation is the process of extracting and refining the fluid of a plant. Aragh of the plants is much more effective on the body than the plant itself. Traditional medicine regards Aragh as a new kind of drug (medicine) that is rarely mentioned in older texts (except for golab). However, the modern medicine regards it as a dosage form of essence, which is dissolved in water. The more the essence, the better the distillate gets. Conclusion: According to the traditional medicine sources, since the time of Hakim Aghil Khorasani, Aragh was used more and more every day. About 100 kinds of Araghs are mentioned in ancient texts, which are extracted from simple plants. Considering the distillation process and the way it performs, and by knowing that Aragh is a plant’s softest and the most influential entity, it seems that it has a huge effect on Arvah and Ghova, the main parts like heart and brain and nervous parts. PMID:27840528

  17. The Dosage Form of Aragh in Treatment, from the Iranian Traditional Medicine Perspective

    PubMed Central

    Adl, Mehdi; Emtiazi, Majid

    2016-01-01

    Background: The Iranian traditional medicine is one of the branches of complementary medicine and it is based on using the dosage forms of plants. One of the most common forms of pharmaceutical plants is Aragh. Due to ease-of-use, distillate is a more acceptable form among the public. In this article, it is attempted to study the usage forms and effects of Aragh according to the valid traditional medicine resources. Methods: This article is a review of Iranian traditional medicine textbooks such as Makhzan-ul-dawiah, Gharabadin Kabir, Cannon of Medicine, and other recent texts on medical plants. Results: According to the traditional medicine, the process of getting Aragh is a kind of distillation, which is performed by using Ghar and Alembic (the equipment that are used in distillation). Distillation is the process of extracting and refining the fluid of a plant. Aragh of the plants is much more effective on the body than the plant itself. Traditional medicine regards Aragh as a new kind of drug (medicine) that is rarely mentioned in older texts (except for golab). However, the modern medicine regards it as a dosage form of essence, which is dissolved in water. The more the essence, the better the distillate gets. Conclusion: According to the traditional medicine sources, since the time of Hakim Aghil Khorasani, Aragh was used more and more every day. About 100 kinds of Araghs are mentioned in ancient texts, which are extracted from simple plants. Considering the distillation process and the way it performs, and by knowing that Aragh is a plant’s softest and the most influential entity, it seems that it has a huge effect on Arvah and Ghova, the main parts like heart and brain and nervous parts. PMID:27516693

  18. The Effects of Problem-Solving Teaching on Creative Thinking among District 2 High School Students in Sari City.

    PubMed

    Nozari, Ali Yazdanpanah; Siamian, Hasan

    2014-12-01

    Nowadays, regarding the learners' needs and social conditions, it is obviously needed to revise and reconsider the traditional methods and approaches in teaching. The problem solving approach is one of the new ways in Teaching and learning process. This study aimed at studying and examining the effect of "problem-solving" approach on creative thinking of high school female students. An experimental method is used for this research. In this research, 342 out of 3047 female-students from Sari high schools were randomly selected. These 342 students were divided into two groups (experimental and control) in which there were seven classrooms. The total number of students in every group was about 171. After testing them with Jamal Abedi creativity test, it was revealed that two groups were equal in creativity score. The tests were done through Requirements. The experimental group was taught by problem solving method for three months while the control group was taught by traditional method. The research results showed that using descriptive indices and t-test for the two independent sample groups in which problem solving teaching method was used in teaching processes had an effect on creativity level in comparison with traditional method used in the control group. Considering the results of this study, the application of problem-solving teaching methods increased the creativity and its components (fluidity, expansion, originality and flexibility) in learners, therefore, it is recommended that students be encouraged to take classes on frequent responses on various topics (variability) and draw attention on different issues, and expand their analysis on elements in particular courses like art (expansion). To enhance the learner's mental flexibility and attention to various aspects, they are encouraged to provide a variety of responses.

  19. Conservation of batik: Conseptual framework of design and process development

    NASA Astrophysics Data System (ADS)

    Syamwil, Rodia

    2018-03-01

    Development of Conservation Batik concept becomes critical due to the recessive of traditional batik as the intangible cultural heritage of humanity. The existence of printed batik, polluting process, and new stream design becomes the consequences of batik industry transformation to creative industry. Conservation Batik was proposed to answer all the threats to traditional batik, in the aspect of technique, process, and motif. However, creativities are also critical to meet consumer satisfaction. Research and development was conducted, start with the initial research in formulating the concept, and exploration of ideas to develop the designs of conservation motifs. In development steps, cyclical process to complete motif with high preferences, in the aspect of aesthetics, productivity, and efficiency. Data were collected through bibliography, documentation, observation, and interview, and analyzed in qualitative methods. The concept of Conservation Batik adopted from the principles of Universitas Negeri Semarang (UNNES) vision, as well as theoretical analyses, and expert judgment. Conservation Batik are assessed from three aspect, design, process, and consumer preferences. Conservation means the effort of safeguarding, promoting, maintaining, and preserving. Concervation Batik concept could be interpreted as batik with: (1) traditional values and authenticity; (2) the values of philosophycal meanings; (3) eco-friendly process with minimum waste; (4) conservation as idea resources of design; and (5) raising up of classic motifs.

  20. Microbial succession and the functional potential during the fermentation of Chinese soy sauce brine

    PubMed Central

    Sulaiman, Joanita; Gan, Han Ming; Yin, Wai-Fong; Chan, Kok-Gan

    2014-01-01

    The quality of traditional Chinese soy sauce is determined by microbial communities and their inter-related metabolic roles in the fermentation tank. In this study, traditional Chinese soy sauce brine samples were obtained periodically to monitor the transitions of the microbial population and functional properties during the 6 months of fermentation process. Whole genome shotgun method revealed that the fermentation brine was dominated by the bacterial genus Weissella and later dominated by the fungal genus Candida. Metabolic reconstruction of the metagenome sequences demonstrated a characteristic profile of heterotrophic fermentation of proteins and carbohydrates. This was supported by the detection of ethanol with stable decrease of pH values. To the best of our knowledge, this is the first study that explores the temporal changes in microbial successions over a period of 6 months, through metagenome shotgun sequencing in traditional Chinese soy sauce fermentation and the biological processes therein. PMID:25400624

  1. Microbial succession and the functional potential during the fermentation of Chinese soy sauce brine.

    PubMed

    Sulaiman, Joanita; Gan, Han Ming; Yin, Wai-Fong; Chan, Kok-Gan

    2014-01-01

    The quality of traditional Chinese soy sauce is determined by microbial communities and their inter-related metabolic roles in the fermentation tank. In this study, traditional Chinese soy sauce brine samples were obtained periodically to monitor the transitions of the microbial population and functional properties during the 6 months of fermentation process. Whole genome shotgun method revealed that the fermentation brine was dominated by the bacterial genus Weissella and later dominated by the fungal genus Candida. Metabolic reconstruction of the metagenome sequences demonstrated a characteristic profile of heterotrophic fermentation of proteins and carbohydrates. This was supported by the detection of ethanol with stable decrease of pH values. To the best of our knowledge, this is the first study that explores the temporal changes in microbial successions over a period of 6 months, through metagenome shotgun sequencing in traditional Chinese soy sauce fermentation and the biological processes therein.

  2. 36 CFR 242.16 - Customary and traditional use determination process.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... specific seasons for many years; (3) A pattern of use consisting of methods and means of harvest which are... which includes the handing down of knowledge of fishing and hunting skills, values, and lore from...

  3. Humidity Measurements: A Psychrometer Suitable for On-Line Data Acquisition.

    ERIC Educational Resources Information Center

    Caporaloni, Marina; Ambrosini, Roberto

    1992-01-01

    Explains the typical design, operation, and calibration of a traditional psychrometer. Presents the method utilized for this class project with design considerations, calibration techniques, remote data sensing schematic, and specifics of the implementation process. (JJK)

  4. A Novel Computer-Aided Design/Computer-Assisted Manufacture Method for One-Piece Removable Partial Denture and Evaluation of Fit.

    PubMed

    Ye, Hongqiang; Li, Xinxin; Wang, Guanbo; Kang, Jing; Liu, Yushu; Sun, Yuchun; Zhou, Yongsheng

    2018-02-15

    To investigate a computer-aided design/computer-aided manufacturing (CAD/CAM) process for producing one-piece removable partial dentures (RPDs) and to evaluate their fits in vitro. A total of 15 one-piece RPDs were designed using dental CAD and reverse engineering software and then fabricated with polyetheretherketone (PEEK) using CAM. The gaps between RPDs and casts were measured and compared with traditional cast framework RPDs. Gaps were lower for one-piece PEEK RPDs compared to traditional RPDs. One-piece RPDs can be manufactured by CAD/CAM, and their fits were better than those of traditional RPDs.

  5. The commercialization of traditional medicine in modern Cambodia

    PubMed Central

    Ros, Bandeth; Lê, Gillian; McPake, Barbara; Fustukian, Suzanne

    2018-01-01

    Abstract Globally, traditional medicine has long been used to address relatively common illness, mental ill health and during childbirth and post-natal care. However, traditional medicine is primarily provided by the private sector and it is unclear how far expenditures on traditional medicine contribute to household impoverishment. A life history method was used to understand the health seeking experience of 24 households over the last 60 years in Cambodia, a country with high out-of-pocket expenditures for health. The life histories suggest that traditional medicine in Cambodia has been undergoing a process of commercialization, with significant impacts on poor households. In the earlier lives of respondents, payments for traditional medicine were reported to have been flexible, voluntary or appropriate to patients’ financial means. In contrast, contemporary practitioners appear to seek immediate cash payments that have frequently led to considerable debt and asset sales by traditional medicine users. Given traditional medicine‘s popularity as a source of treatment in Cambodia and its potential to contribute to household impoverishment, we suggest that it needs to be included in a national conversation about achieving Universal Health Coverage in the country. PMID:29040469

  6. An initial investigation into the validity of a computer-based auditory processing assessment (Feather Squadron).

    PubMed

    Barker, Matthew D; Purdy, Suzanne C

    2016-01-01

    This research investigates a novel method for identifying and measuring school-aged children with poor auditory processing through a tablet computer. Feasibility and test-retest reliability are investigated by examining the percentage of Group 1 participants able to complete the tasks and developmental effects on performance. Concurrent validity was investigated against traditional tests of auditory processing using Group 2. There were 847 students aged 5 to 13 years in group 1, and 46 aged 5 to 14 years in group 2. Some tasks could not be completed by the youngest participants. Significant correlations were found between results of most auditory processing areas assessed by the Feather Squadron test and traditional auditory processing tests. Test-retest comparisons indicated good reliability for most of the Feather Squadron assessments and some of the traditional tests. The results indicate the Feather Squadron assessment is a time-efficient, feasible, concurrently valid, and reliable approach for measuring auditory processing in school-aged children. Clinically, this may be a useful option for audiologists when performing auditory processing assessments as it is a relatively fast, engaging, and easy way to assess auditory processing abilities. Research is needed to investigate further the construct validity of this new assessment by examining the association between performance on Feather Squadron and objective evoked potential, lesion studies, and/or functional imaging measures of auditory function.

  7. Write Another Poem about Marigold: Meaningful Writing as a Process of Change.

    ERIC Educational Resources Information Center

    Teichmann, Sandra Gail

    1995-01-01

    Considers a process approach toward the goal of meaningful writing which may aid in positive personal change. Outlines recent criticism of contemporary poetry; argues against tradition and practice of craft in writing poetry. Proposes a means of writing centered on a method of inquiry involving elements of self-involvement, curiosity, and risk to…

  8. NREL Develops Novel Method to Produce Renewable Acrylonitrile | News | NREL

    Science.gov Websites

    to Produce Renewable Acrylonitrile December 7, 2017 Research paves the way for cost-competitive , and Eric Karp, part of the NREL team working on a cost-competitive, sustainable process for creating traditional process in terms of cost and yield. Now, new NREL research is showing promise toward achieving

  9. An Examination of Native and Immigrant Students' Social Networking Using the College Search and Selection Process

    ERIC Educational Resources Information Center

    Neimeyer, Bruce Carlton

    2009-01-01

    This dissertation explores the use of formal and informal networks through cyber- and traditional communication methods in the college search and selection process by native and immigrant students to examine various postulates and propositions of social capital theory. In addition, the analysis of cybernetworks used by disadvantaged, college bound…

  10. Taguchi's off line method and Multivariate loss function approach for quality management and optimization of process parameters -A review

    NASA Astrophysics Data System (ADS)

    Bharti, P. K.; Khan, M. I.; Singh, Harbinder

    2010-10-01

    Off-line quality control is considered to be an effective approach to improve product quality at a relatively low cost. The Taguchi method is one of the conventional approaches for this purpose. Through this approach, engineers can determine a feasible combination of design parameters such that the variability of a product's response can be reduced and the mean is close to the desired target. The traditional Taguchi method was focused on ensuring good performance at the parameter design stage with one quality characteristic, but most products and processes have multiple quality characteristics. The optimal parameter design minimizes the total quality loss for multiple quality characteristics. Several studies have presented approaches addressing multiple quality characteristics. Most of these papers were concerned with maximizing the parameter combination of signal to noise (SN) ratios. The results reveal the advantages of this approach are that the optimal parameter design is the same as the traditional Taguchi method for the single quality characteristic; the optimal design maximizes the amount of reduction of total quality loss for multiple quality characteristics. This paper presents a literature review on solving multi-response problems in the Taguchi method and its successful implementation in various industries.

  11. Business Process-Based Resource Importance Determination

    NASA Astrophysics Data System (ADS)

    Fenz, Stefan; Ekelhart, Andreas; Neubauer, Thomas

    Information security risk management (ISRM) heavily depends on realistic impact values representing the resources’ importance in the overall organizational context. Although a variety of ISRM approaches have been proposed, well-founded methods that provide an answer to the following question are still missing: How can business processes be used to determine resources’ importance in the overall organizational context? We answer this question by measuring the actual importance level of resources based on business processes. Therefore, this paper presents our novel business process-based resource importance determination method which provides ISRM with an efficient and powerful tool for deriving realistic resource importance figures solely from existing business processes. The conducted evaluation has shown that the calculation results of the developed method comply to the results gained in traditional workshop-based assessments.

  12. Dimensional Precision Research of Wax Molding Rapid Prototyping based on Droplet Injection

    NASA Astrophysics Data System (ADS)

    Mingji, Huang; Geng, Wu; yan, Shan

    2017-11-01

    The traditional casting process is complex, the mold is essential products, mold quality directly affect the quality of the product. With the method of rapid prototyping 3D printing to produce mold prototype. The utility wax model has the advantages of high speed, low cost and complex structure. Using the orthogonal experiment as the main method, analysis each factors of size precision. The purpose is to obtain the optimal process parameters, to improve the dimensional accuracy of production based on droplet injection molding.

  13. New criteria for the characterization of traditional East Asian papers.

    PubMed

    Avataneo, Chiara; Sablier, Michel

    2017-01-01

    We report a pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS) method capable of analyzing traditional East Asian papers. The method proposed is based on rapid and easy single step Py-GC/MS analysis that can be carried out with a minimum amount of matter, in the few microgram range. Three reference papers manufactured from kozo (Broussonetia kazinoki Siebold & Zucc.), mitsumata (Edgeworthia chrysantha Lindl.), and gampi (Wikstroemia sikokiana Franch. & Sav.) with the traditional hand paper making processes were examined. The method allows discrimination between terpenic and steroid compounds, which were revealed as chemical markers of origin of the plant fibers. Each paper investigated was found to have characteristic pyrolysis fingerprints that were unique to the traditional handmade paper, demonstrating the potential for differentiation of these biochemical components of fiber plants on East Asian papers towards identification and conservation of cultural heritage. The investigation on Py-GC/MS was extended to liquid extraction followed by GC/MS analysis to characterize the biochemical components of fiber plants. The main contribution of this study is to provide molecular criteria for discriminating plant species used for traditional East Asian hand papermaking. Py-GC/MS complements efficiently microscope identification especially for adverse cases. A case study of archaeological Chinese paper painting artefacts was thereafter successfully investigated to address informative potential and efficiency of the criteria of identification on ancient and degraded East Asian paperworks.

  14. Personality preference distribution of dental students admitted to one dental school using different selection methods.

    PubMed

    von Bergmann, Hsingchi; Dalrymple, Kirsten R; Shuler, Charles F

    2014-04-01

    This study sought to determine whether using the Myers-Briggs Type Indicator (MBTI) would detect differences in personality preferences in first-year dental students admitted to the same dental school through different admission methods. First-year dental students admitted in 2000 and 2001 were given the MBTI instrument during orientation prior to the start of classes. In fall 2000, the Class of 2004 had 140 students, with 116 in the traditional track and twenty-four in the parallel problem-based learning (PBL) track. In fall 2001, the Class of 2005 had 144 students, all enrolled in the PBL curriculum. All students admitted to the PBL track had experienced a process that included evaluation of their participation in a small group. Students in the traditional track had individual interviews with faculty members. Both student groups were required to meet the same baseline grade point average and Dental Admission Test standards. In 2000, the PBL students showed personality preferences that were distinctly different from the personality preferences of traditional track students in the categories of Extroversion (89 percent PBL, 44 percent traditional) and Thinking (72 percent PBL, 39 percent traditional). In 2001, the all-PBL class retained the trend towards Extroversion (69 percent). This study suggests that admission method may effectively change the personality preference distribution exhibited by the students who are admitted to dental school.

  15. Using Mosix for Wide-Area Compuational Resources

    USGS Publications Warehouse

    Maddox, Brian G.

    2004-01-01

    One of the problems with using traditional Beowulf-type distributed processing clusters is that they require an investment in dedicated computer resources. These resources are usually needed in addition to pre-existing ones such as desktop computers and file servers. Mosix is a series of modifications to the Linux kernel that creates a virtual computer, featuring automatic load balancing by migrating processes from heavily loaded nodes to less used ones. An extension of the Beowulf concept is to run a Mosixenabled Linux kernel on a large number of computer resources in an organization. This configuration would provide a very large amount of computational resources based on pre-existing equipment. The advantage of this method is that it provides much more processing power than a traditional Beowulf cluster without the added costs of dedicating resources.

  16. On the Interplay Between Adhesion Strength and Tensile Properties of Thermal Spray Coated Laminates—Part II: Low-Velocity Thermal Spray Coatings

    NASA Astrophysics Data System (ADS)

    Luo, Xiaotao; Smith, Gregory M.; Sampath, Sanjay

    2018-02-01

    In this two-part study, uniaxial tensile testing was used to evaluate coating/substrate bonding and compared with traditional ASTM C633 bond pull test results for thermal spray (TS) coated steel laminates. In Part I, the rationale, methodology, and applicability of the test to high-velocity TS coatings were demonstrated. In this Part II, the method was investigated for low-velocity TS processes (air plasma spray and arc spray) on equivalent materials. Ni and Ni-5wt.%Al coatings were deposited on steel substrates with three different roughness levels and tested using both uniaxial tensile and ASTM C633 methods. The results indicate the uniaxial tensile approach provides useful information about the nature of the coating/substrate bonding and goes beyond the traditional bond pull test in providing insightful information on the load sharing processes across the interface. Additionally, this proposed methodology alleviates some of the longstanding shortcomings and potentially reduces error associated with the traditional ASTM C633 test. The mechanisms governing the load transfer between the substrate and the coating were investigated, and the influence of Al in the coating material evaluated.

  17. Semi-automating the manual literature search for systematic reviews increases efficiency.

    PubMed

    Chapman, Andrea L; Morgan, Laura C; Gartlehner, Gerald

    2010-03-01

    To minimise retrieval bias, manual literature searches are a key part of the search process of any systematic review. Considering the need to have accurate information, valid results of the manual literature search are essential to ensure scientific standards; likewise efficient approaches that minimise the amount of personnel time required to conduct a manual literature search are of great interest. The objective of this project was to determine the validity and efficiency of a new manual search method that utilises the scopus database. We used the traditional manual search approach as the gold standard to determine the validity and efficiency of the proposed scopus method. Outcome measures included completeness of article detection and personnel time involved. Using both methods independently, we compared the results based on accuracy of the results, validity and time spent conducting the search, efficiency. Regarding accuracy, the scopus method identified the same studies as the traditional approach indicating its validity. In terms of efficiency, using scopus led to a time saving of 62.5% compared with the traditional approach (3 h versus 8 h). The scopus method can significantly improve the efficiency of manual searches and thus of systematic reviews.

  18. Sterilization processes. Meeting the demands of today's health care technology.

    PubMed

    Crow, S

    1993-09-01

    Universal Precautions dictate sterilization for all invasive equipment that break the blood barrier; however, current methods of sterilization, such as steam and ethylene oxide gas (ETO), are not compatible with many of the delicate, heat-sensitive surgical instruments used in modern health care. In addition, traditional sterilization methods are often too time consuming for practical use in the operating room. Clearly, new sterilization processes need to be developed. In this article, the criteria modern sterilization processes must meet and how some manufacturers plan to meet this challenge are discussed. In addition, the pros and cons of using peracetic acid (the newest sterilization process currently available) are examined.

  19. Rapid microscale in-gel processing and digestion of proteins using surface acoustic waves.

    PubMed

    Kulkarni, Ketav P; Ramarathinam, Sri H; Friend, James; Yeo, Leslie; Purcell, Anthony W; Perlmutter, Patrick

    2010-06-21

    A new method for in-gel sample processing and tryptic digestion of proteins is described. Sample preparation, rehydration, in situ digestion and peptide extraction from gel slices are dramatically accelerated by treating the gel slice with surface acoustic waves (SAWs). Only 30 minutes total workflow time is required for this new method to produce base peak chromatograms (BPCs) of similar coverage and intensity to those observed for traditional processing and overnight digestion. Simple set up, good reproducibility, excellent peptide recoveries, rapid turnover of samples and high confidence protein identifications put this technology at the fore-front of the next generation of proteomics sample processing tools.

  20. Bridging the gap between finance and clinical operations with activity-based cost management.

    PubMed

    Storfjell, J L; Jessup, S

    1996-12-01

    Activity-based cost management (ABCM) is an exciting management tool that links financial information with operations. By determining the costs of specific activities and processes, nurse managers accurately determine true costs of services more accurately than traditional cost accounting methods, and then can target processes for improvement and monitor them for change and improvement. The authors describe the ABCM process applied to nursing management situations.

  1. Ambient Noise Correlation Amplitudes and Local Site Response

    NASA Astrophysics Data System (ADS)

    Bowden, D. C.; Tsai, V. C.; Lin, F. C.

    2014-12-01

    We investigate amplitudes from ambient noise cross correlations in a spatially dense array. Our study of wave propagation effects and ambient noise is focused on the Long Beach Array, with more than 5000 single component geophones in an area of about 100 square kilometers, providing high resolution imaging of shallow crustal features. The method allows for observations of ground properties like site response and attenuation, which can well supplement traditional velocity models and simulations for seismic hazard. Traditional ambient noise cross correlations have proven to be an effective means of measuring velocity information about surface waves, but the amplitudes of such signals in traditional processing are often distorted. We discuss a method of signal processing which preserves relative amplitudes of signals within an array, and the subsequent processing to track wave motion across the array. Previous work showed promising correlation to known local structure, but did not represent a thorough application of tomographic methods. Now we extend the methodology to more robustly consider wavefront focusing and defocusing, interference with higher modes, and discuss the differing effects of local site response, attenuation, and scattering. Application of Helmholtz tomography and determination of local site amplification has previously been demonstrated using earthquake data on the continental scale with USArray, but the exploitation of the ambient noise field is required both for the higher frequencies needed by seismic hazard studies and for the short deployment time of a Long Beach scale array. We outline both the successes and shortcomings of the methodology, and show how it can be extended for use on future arrays.

  2. Unidirectional Fabric Drape Testing Method

    PubMed Central

    Mei, Zaihuan; Yang, Jingzhi; Zhou, Ting; Zhou, Hua

    2015-01-01

    In most cases, fabrics such as curtains, skirts, suit pants and so on are draped under their own gravity parallel to fabric plane while the gravity is perpendicular to fabric plane in traditional drape testing method. As a result, it does not conform to actual situation and the test data is not convincing enough. To overcome this problem, this paper presents a novel method which simulates the real mechanical conditions and ensures the gravity is parallel to the fabric plane. This method applied a low-cost Kinect Sensor device to capture the 3-dimensional (3D) drape profile, thus we obtained the drape degree parameters and aesthetic parameters by 3D reconstruction and image processing and analysis techniques. The experiment was conducted on our self-devised drape-testing instrument by choosing different kinds of weave structure fabrics as our testing samples and the results were compared with those of traditional method and subjective evaluation. Through regression and correlation analysis we found that this novel testing method was significantly correlated with the traditional and subjective evaluation method. We achieved a new, non-contact 3D measurement method for drape testing, namely unidirectional fabric drape testing method. This method is more suitable for evaluating drape behavior because it is more in line with actual mechanical conditions of draped fabrics and has a well consistency with the requirements of visual and aesthetic style of fabrics. PMID:26600387

  3. Pre-Nursing Students Perceptions of Traditional and Inquiry Based Chemistry Laboratories

    NASA Astrophysics Data System (ADS)

    Rogers, Jessica

    This paper describes a process that attempted to meet the needs of undergraduate students in a pre-nursing chemistry class. The laboratory was taught in traditional verification style and students were surveyed to assess their perceptions of the educational goals of the laboratory. A literature review resulted in an inquiry based method and analysis of the needs of nurses resulted in more application based activities. This new inquiry format was implemented the next semester, the students were surveyed at the end of the semester and results were compared to the previous method. Student and instructor response to the change in format was positive. Students in the traditional format placed goals concerning technique above critical thinking and felt the lab was easy to understand and carry out. Students in the inquiry based lab felt they learned more critical thinking skills and enjoyed the independence of designing experiments and answering their own questions.

  4. Leaking in history space: A way to analyze systems subjected to arbitrary driving

    NASA Astrophysics Data System (ADS)

    Kaszás, Bálint; Feudel, Ulrike; Tél, Tamás

    2018-03-01

    Our aim is to unfold phase space structures underlying systems with a drift in their parameters. Such systems are non-autonomous and belong to the class of non-periodically driven systems where the traditional theory of chaos (based e.g., on periodic orbits) does not hold. We demonstrate that even such systems possess an underlying topological horseshoe-like structure at least for a finite period of time. This result is based on a specifically developed method which allows to compute the corresponding time-dependent stable and unstable foliations. These structures can be made visible by prescribing a certain type of history for an ensemble of trajectories in phase space and by analyzing the trajectories fulfilling this constraint. The process can be considered as a leaking in history space—a generalization of traditional leaking, a method that has become widespread in traditional chaotic systems, to leaks depending on time.

  5. Microwave-Assisted Hydro-Distillation of Essential Oil from Rosemary: Comparison with Traditional Distillation.

    PubMed

    Moradi, Sara; Fazlali, Alireza; Hamedi, Hamid

    2018-01-01

    Hydro-distillation (HD) method is a traditional technique which is used in most industrial companies. Microwave-assisted Hydro-distillation (MAHD) is an advanced HD technique utilizing a microwave oven in the extraction process. In this research, MAHD of essential oils from the aerial parts (leaves) of rosemary ( Rosmarinus officinalis L. ) was studied and the results were compared with those of the conventional HD in terms of extraction time, extraction efficiency, chemical composition, quality of the essential oils and cost of the operation. Microwave hydro-distillation was superior in terms of saving energy and extraction time (30 min , compared to 90 min in HD). Chromatography was used for quantity analysis of the essential oils composition. Quality of essential oil improved in MAHD method due to an increase of 17% in oxygenated compounds. Consequently, microwave hydro-distillation can be used as a substitute of traditional hydro-distillation.

  6. Comparison of elicitation methods for moral and affective beliefs in the theory of planned behaviour.

    PubMed

    Dean, M; Arvola, A; Vassallo, M; Lähteenmäki, L; Raats, M M; Saba, A; Shepherd, R

    2006-09-01

    Although the theory of planned behaviour (TPB) has been applied successfully in the area of food choice, it has been criticized for its pure utilitarian approach to the factors determining behaviour. Despite the increase in predictive power of the model with added components such as affective attitude and moral and ethical concerns, in most studies the elicitation process still only addresses people's utilitarian beliefs about the behaviour with little attention paid to other aspects. This study compares the traditional method of elicitation of advantages and disadvantages with two other methods (word association and open-ended) in the elicitations of beliefs, attitudes and moral concerns in relation to the consumption of organic foods. Results show the traditional method to be best for eliciting cognitive beliefs, open-ended emotion task for eliciting emotional beliefs and open-ended beliefs task best for moral concerns. The advantages and disadvantages of each method are discussed.

  7. A clustering method of Chinese medicine prescriptions based on modified firefly algorithm.

    PubMed

    Yuan, Feng; Liu, Hong; Chen, Shou-Qiang; Xu, Liang

    2016-12-01

    This paper is aimed to study the clustering method for Chinese medicine (CM) medical cases. The traditional K-means clustering algorithm had shortcomings such as dependence of results on the selection of initial value, trapping in local optimum when processing prescriptions form CM medical cases. Therefore, a new clustering method based on the collaboration of firefly algorithm and simulated annealing algorithm was proposed. This algorithm dynamically determined the iteration of firefly algorithm and simulates sampling of annealing algorithm by fitness changes, and increased the diversity of swarm through expansion of the scope of the sudden jump, thereby effectively avoiding premature problem. The results from confirmatory experiments for CM medical cases suggested that, comparing with traditional K-means clustering algorithms, this method was greatly improved in the individual diversity and the obtained clustering results, the computing results from this method had a certain reference value for cluster analysis on CM prescriptions.

  8. Using the Halstead-Reitan Battery to diagnose brain damage: a comparison of the predictive power of traditional techniques to Rohling's Interpretive Method.

    PubMed

    Rohling, Martin L; Williamson, David J; Miller, L Stephen; Adams, Russell L

    2003-11-01

    The aim of this project was to validate an alternative global measure of neurocognitive impairment (Rohling Interpretive Method, or RIM) that could be generated from data gathered from a flexible battery approach. A critical step in this process is to establish the utility of the technique against current standards in the field. In this paper, we compared results from the Rohling Interpretive Method to those obtained from the General Neuropsychological Deficit Scale (GNDS; Reitan & Wolfson, 1988) and the Halstead-Russell Average Impairment Rating (AIR; Russell, Neuringer & Goldstein, 1970) on a large previously published sample of patients assessed with the Halstead-Reitan Battery (HRB). Findings support the use of the Rohling Interpretive Method in producing summary statistics similar in diagnostic sensitivity and specificity to the traditional HRB indices.

  9. Inactivation of Vibrio parahaemolyticus in hard clams (Mercanaria mercanaria) by high hydrostatic pressure (HHP) and the effect of HHP on the physical characteristics of hard clam meat.

    PubMed

    Mootian, Gabriel K; Flimlin, George E; Karwe, Mukund V; Schaffner, Donald W

    2013-02-01

    Shellfish may internalize dangerous pathogens during filter feeding. Traditional methods of depuration have been found ineffective against certain pathogens. The objective was to explore high hydrostatic pressure (HHP) as an alternative to the traditional depuration process. The effect of HHP on the survival of Vibrio parahaemolyticus in live clams (Mercanaria mercanaria) and the impact of HHP on physical characteristics of clam meat were investigated. Clams were inoculated with up to 7 log CFU/g of a cocktail of V. parahaemolyticus strains via filter feeding. Clams were processed at pressures ranging from 250 to 552 MPa for hold times ranging between 2 and 6 min. Processing conditions of 450 MPa for 4 min and 350 MPa for 6 min reduced the initial concentration of V. parahaemolyticus to a nondetectable level (<10(1) CFU/g), achieving >5 log reductions. The volume of clam meat (processed in shell) increased with negligible change in mass after exposure to pressure at 552 MPa for 3 min, while the drip loss was reduced. Clams processed at 552 MPa were softer compared to those processed at 276 MPa. However, all HHP processed clams were found to be harder compared to unprocessed. The lightness (L*) of the meat increased although the redness (a*) decreased with increasing pressure. Although high pressure-processed clams may pose a significantly lower risk from V. parahaemolyticus, the effect of the accompanied physical changes on the consumer's decision to purchase HHP clams remains to be determined. Shellfish may contain dangerous foodborne pathogens. Traditional methods of removing those pathogen have been found ineffective against certain pathogens. The objective of this research was to determine the effect of high hydrostatic pressure on V. parahaemolyticus in clams. Processing conditions of 450 MPa for 4 min and 350 MPa for 6 min reduced the initial concentration of V. parahaemolyticus to a nondetectable level, achieving >5 log reductions. © 2013 Institute of Food Technologists®

  10. Implementing a Flipped Classroom: A Case Study of Biology Teaching in a Greek High School

    ERIC Educational Resources Information Center

    Gariou-Papalexiou, Angeliki; Papadakis, Spyros; Manousou, Evangelia; Georgiadu, Irene

    2017-01-01

    The purpose of this study was to investigate the application of the model of the "flipped classroom" as a complementary method to school distance education in junior high school Biology. The "flipped classroom" model attempts a different way of organizing the educational process according to which the traditional methods of…

  11. Art Dialogue Methods: Phronèsis and Its Potential for Restoring an Embodied Moral Authority in Local Communities

    ERIC Educational Resources Information Center

    Muijen, Heidi S. C. A.; Brohm, René

    2018-01-01

    We put forward Art-Dialogue-Methods (ADM) as an inquiry for practical wisdom within communities. It draws from a series of methodological traditions like artistic inquiry, participatory action research and narrative research. The practice of ADM could facilitate healing processes in fractured communities and organisations in today's world. ADM…

  12. Near ground level sensing for spatial analysis of vegetation

    NASA Technical Reports Server (NTRS)

    Sauer, Tom; Rasure, John; Gage, Charlie

    1991-01-01

    Measured changes in vegetation indicate the dynamics of ecological processes and can identify the impacts from disturbances. Traditional methods of vegetation analysis tend to be slow because they are labor intensive; as a result, these methods are often confined to small local area measurements. Scientists need new algorithms and instruments that will allow them to efficiently study environmental dynamics across a range of different spatial scales. A new methodology that addresses this problem is presented. This methodology includes the acquisition, processing, and presentation of near ground level image data and its corresponding spatial characteristics. The systematic approach taken encompasses a feature extraction process, a supervised and unsupervised classification process, and a region labeling process yielding spatial information.

  13. Traditional Chinese Biotechnology

    NASA Astrophysics Data System (ADS)

    Xu, Yan; Wang, Dong; Fan, Wen Lai; Mu, Xiao Qing; Chen, Jian

    The earliest industrial biotechnology originated in ancient China and developed into a vibrant industry in traditional Chinese liquor, rice wine, soy sauce, and vinegar. It is now a significant component of the Chinese economy valued annually at about 150 billion RMB. Although the production methods had existed and remained basically unchanged for centuries, modern developments in biotechnology and related fields in the last decades have greatly impacted on these industries and led to numerous technological innovations. In this chapter, the main biochemical processes and related technological innovations in traditional Chinese biotechnology are illustrated with recent advances in functional microbiology, microbial ecology, solid-state fermentation, enzymology, chemistry of impact flavor compounds, and improvements made to relevant traditional industrial facilities. Recent biotechnological advances in making Chinese liquor, rice wine, soy sauce, and vinegar are reviewed.

  14. PREFACE: MARINE AND COASTAL APPLICATIONS IN LANDSCAPE ECOLOGY

    EPA Science Inventory

    Landscape ecology traditionally has been limited to the study of terrestrial systems; however, the questions and methods defining the science are equally relevant for marine and coastal systems. The reciprocal relationship between spatial pattern and ecological processes and the...

  15. Bayesian Computation for Log-Gaussian Cox Processes: A Comparative Analysis of Methods

    PubMed Central

    Teng, Ming; Nathoo, Farouk S.; Johnson, Timothy D.

    2017-01-01

    The Log-Gaussian Cox Process is a commonly used model for the analysis of spatial point pattern data. Fitting this model is difficult because of its doubly-stochastic property, i.e., it is an hierarchical combination of a Poisson process at the first level and a Gaussian Process at the second level. Various methods have been proposed to estimate such a process, including traditional likelihood-based approaches as well as Bayesian methods. We focus here on Bayesian methods and several approaches that have been considered for model fitting within this framework, including Hamiltonian Monte Carlo, the Integrated nested Laplace approximation, and Variational Bayes. We consider these approaches and make comparisons with respect to statistical and computational efficiency. These comparisons are made through several simulation studies as well as through two applications, the first examining ecological data and the second involving neuroimaging data. PMID:29200537

  16. Using natural language processing to identify problem usage of prescription opioids.

    PubMed

    Carrell, David S; Cronkite, David; Palmer, Roy E; Saunders, Kathleen; Gross, David E; Masters, Elizabeth T; Hylan, Timothy R; Von Korff, Michael

    2015-12-01

    Accurate and scalable surveillance methods are critical to understand widespread problems associated with misuse and abuse of prescription opioids and for implementing effective prevention and control measures. Traditional diagnostic coding incompletely documents problem use. Relevant information for each patient is often obscured in vast amounts of clinical text. We developed and evaluated a method that combines natural language processing (NLP) and computer-assisted manual review of clinical notes to identify evidence of problem opioid use in electronic health records (EHRs). We used the EHR data and text of 22,142 patients receiving chronic opioid therapy (≥70 days' supply of opioids per calendar quarter) during 2006-2012 to develop and evaluate an NLP-based surveillance method and compare it to traditional methods based on International Classification of Disease, Ninth Edition (ICD-9) codes. We developed a 1288-term dictionary for clinician mentions of opioid addiction, abuse, misuse or overuse, and an NLP system to identify these mentions in unstructured text. The system distinguished affirmative mentions from those that were negated or otherwise qualified. We applied this system to 7336,445 electronic chart notes of the 22,142 patients. Trained abstractors using a custom computer-assisted software interface manually reviewed 7751 chart notes (from 3156 patients) selected by the NLP system and classified each note as to whether or not it contained textual evidence of problem opioid use. Traditional diagnostic codes for problem opioid use were found for 2240 (10.1%) patients. NLP-assisted manual review identified an additional 728 (3.1%) patients with evidence of clinically diagnosed problem opioid use in clinical notes. Inter-rater reliability among pairs of abstractors reviewing notes was high, with kappa=0.86 and 97% agreement for one pair, and kappa=0.71 and 88% agreement for another pair. Scalable, semi-automated NLP methods can efficiently and accurately identify evidence of problem opioid use in vast amounts of EHR text. Incorporating such methods into surveillance efforts may increase prevalence estimates by as much as one-third relative to traditional methods. Copyright © 2015. Published by Elsevier Ireland Ltd.

  17. Sentiment analysis of feature ranking methods for classification accuracy

    NASA Astrophysics Data System (ADS)

    Joseph, Shashank; Mugauri, Calvin; Sumathy, S.

    2017-11-01

    Text pre-processing and feature selection are important and critical steps in text mining. Text pre-processing of large volumes of datasets is a difficult task as unstructured raw data is converted into structured format. Traditional methods of processing and weighing took much time and were less accurate. To overcome this challenge, feature ranking techniques have been devised. A feature set from text preprocessing is fed as input for feature selection. Feature selection helps improve text classification accuracy. Of the three feature selection categories available, the filter category will be the focus. Five feature ranking methods namely: document frequency, standard deviation information gain, CHI-SQUARE, and weighted-log likelihood -ratio is analyzed.

  18. A fast positioning algorithm for the asymmetric dual Mach-Zehnder interferometric infrared fiber vibration sensor

    NASA Astrophysics Data System (ADS)

    Jiang, Junfeng; An, Jianchang; Liu, Kun; Ma, Chunyu; Li, Zhichen; Liu, Tiegen

    2017-09-01

    We propose a fast positioning algorithm for the asymmetric dual Mach-Zehnder interferometric infrared fiber vibration sensor. Using the approximately derivation method and the enveloping detection method, we successfully eliminate the asymmetry of the interference outputs and improve the processing speed. A positioning measurement experiment was carried out to verify the effectiveness of the proposed algorithm. At the sensing length of 85 km, the experimental results show that the mean positioning error is 18.9 m and the mean processing time is 116 ms. The processing speed is improved by 5 times compared to what can be achieved by using the traditional time-frequency analysis-based positioning method.

  19. Improved Linear Algebra Methods for Redshift Computation from Limited Spectrum Data - II

    NASA Technical Reports Server (NTRS)

    Foster, Leslie; Waagen, Alex; Aijaz, Nabella; Hurley, Michael; Luis, Apolo; Rinsky, Joel; Satyavolu, Chandrika; Gazis, Paul; Srivastava, Ashok; Way, Michael

    2008-01-01

    Given photometric broadband measurements of a galaxy, Gaussian processes may be used with a training set to solve the regression problem of approximating the redshift of this galaxy. However, in practice solving the traditional Gaussian processes equation is too slow and requires too much memory. We employed several methods to avoid this difficulty using algebraic manipulation and low-rank approximation, and were able to quickly approximate the redshifts in our testing data within 17 percent of the known true values using limited computational resources. The accuracy of one method, the V Formulation, is comparable to the accuracy of the best methods currently used for this problem.

  20. Rapid and Low-cost Prototyping of Medical Devices Using 3D Printed Molds for Liquid Injection Molding

    PubMed Central

    Chung, Philip; Heller, J. Alex; Etemadi, Mozziyar; Ottoson, Paige E.; Liu, Jonathan A.; Rand, Larry; Roy, Shuvo

    2014-01-01

    Biologically inert elastomers such as silicone are favorable materials for medical device fabrication, but forming and curing these elastomers using traditional liquid injection molding processes can be an expensive process due to tooling and equipment costs. As a result, it has traditionally been impractical to use liquid injection molding for low-cost, rapid prototyping applications. We have devised a method for rapid and low-cost production of liquid elastomer injection molded devices that utilizes fused deposition modeling 3D printers for mold design and a modified desiccator as an injection system. Low costs and rapid turnaround time in this technique lower the barrier to iteratively designing and prototyping complex elastomer devices. Furthermore, CAD models developed in this process can be later adapted for metal mold tooling design, enabling an easy transition to a traditional injection molding process. We have used this technique to manufacture intravaginal probes involving complex geometries, as well as overmolding over metal parts, using tools commonly available within an academic research laboratory. However, this technique can be easily adapted to create liquid injection molded devices for many other applications. PMID:24998993

  1. Effects of processing adjuvants on traditional Chinese herbs.

    PubMed

    Chen, Lin-Lin; Verpoorte, Robert; Yen, Hung-Rong; Peng, Wen-Huang; Cheng, Yung-Chi; Chao, Jung; Pao, Li-Heng

    2018-04-01

    Processing of Chinese medicines is a pharmaceutical technique that transforms medicinal raw materials into decoction pieces for use in different therapies. Various adjuvants, such as vinegar, wine, honey, and brine, are used in the processing to enhance the efficacy and reduce the toxicity of crude drugs. Proper processing is essential to ensure the quality and safety of traditional Chinese medicines (TCMs). Therefore, sound knowledge of processing principles is crucial to the standardized use of these processing adjuvants and to facilitate the production and clinical use of decoction pieces. Many scientific reports have indicated the synergistic effects of processing mechanisms on the chemistry, pharmacology, and pharmacokinetics of the active ingredients in TCMs. Under certain conditions, adjuvants change the content of active or toxic components in drugs by chemical or physical transformation, increase or decrease drug dissolution, exert their own pharmacological effects, or alter drug pharmacokinetics. This review summarizes various processing methods adopted in the last two decades, and highlights current approaches to identify the effects of processing parameters on TCMs. Copyright © 2018. Published by Elsevier B.V.

  2. Manufacturing PDMS micro lens array using spin coating under a multiphase system

    NASA Astrophysics Data System (ADS)

    Sun, Rongrong; Yang, Hanry; Rock, D. Mitchell; Danaei, Roozbeh; Panat, Rahul; Kessler, Michael R.; Li, Lei

    2017-05-01

    The development of micro lens arrays has garnered much interest due to increased demand of miniaturized systems. Traditional methods for manufacturing micro lens arrays have several shortcomings. For example, they require expensive facilities and long lead time, and traditional lens materials (i.e. glass) are typically heavy, costly and difficult to manufacture. In this paper, we explore a method for manufacturing a polydimethylsiloxane (PDMS) micro lens array using a simple spin coating technique. The micro lens array, formed under an interfacial tension dominated system, and the influence of material properties and process parameters on the fabricated lens shape are examined. The lenses fabricated using this method show comparable optical properties—including surface finish and image quality—with a reduced cost and manufacturing lead time.

  3. Using Penelope to assess the correctness of NASA Ada software: A demonstration of formal methods as a counterpart to testing

    NASA Technical Reports Server (NTRS)

    Eichenlaub, Carl T.; Harper, C. Douglas; Hird, Geoffrey

    1993-01-01

    Life-critical applications warrant a higher level of software reliability than has yet been achieved. Since it is not certain that traditional methods alone can provide the required ultra reliability, new methods should be examined as supplements or replacements. This paper describes a mathematical counterpart to the traditional process of empirical testing. ORA's Penelope verification system is demonstrated as a tool for evaluating the correctness of Ada software. Grady Booch's Ada calendar utility package, obtained through NASA, was specified in the Larch/Ada language. Formal verification in the Penelope environment established that many of the package's subprograms met their specifications. In other subprograms, failed attempts at verification revealed several errors that had escaped detection by testing.

  4. Design and Realization of Controllable Ultrasonic Fault Detector Automatic Verification System

    NASA Astrophysics Data System (ADS)

    Sun, Jing-Feng; Liu, Hui-Ying; Guo, Hui-Juan; Shu, Rong; Wei, Kai-Li

    The ultrasonic flaw detection equipment with remote control interface is researched and the automatic verification system is developed. According to use extensible markup language, the building of agreement instruction set and data analysis method database in the system software realizes the controllable designing and solves the diversification of unreleased device interfaces and agreements. By using the signal generator and a fixed attenuator cascading together, a dynamic error compensation method is proposed, completes what the fixed attenuator does in traditional verification and improves the accuracy of verification results. The automatic verification system operating results confirms that the feasibility of the system hardware and software architecture design and the correctness of the analysis method, while changes the status of traditional verification process cumbersome operations, and reduces labor intensity test personnel.

  5. The Evaluation of Synchronous Distance Ear Training Compared to the Traditional Ear Training

    ERIC Educational Resources Information Center

    Karahan, Ahmet Suat

    2014-01-01

    It is clearly seen that distance education, spreading all over the world recently, is increasingly used in music education process. That the method brings great flexibility to the teaching-learning process destroys the limits depending on time and space and it can easily reach wide audiences and so on outstanding features are the main factors…

  6. Propagation method for persistent high yield of diverse Listeria phages on permissive hosts at refrigeration temperatures.

    PubMed

    Radford, Devon R; Ahmadi, Hanie; Leon-Velarde, Carlos G; Balamurugan, Sampathkumar

    2016-10-01

    The efficient production of a high concentration of bacteriophage in large volumes has been a limiting factor in the exploration of the true potential of these organisms for biotechnology, agriculture and medicine. Traditional methods focus on generating small volumes of highly concentrated samples as the end product of extensive mechanical and osmotic processing. To function at an industrial scale mandates extensive investment in infrastructure and input materials not feasible for many smaller facilities. To address this, we developed a novel, scalable, generic method for producing significantly higher titer psychrophilic phage (P < 2.0 × 10(-6)), 2- to 4-fold faster than traditional methods. We generate renewable high yields from single source cultures by propagating phage under refrigeration conditions in which Listeria, Yersinia and their phages grow in equilibrium. Diverse Yersinia and Listeria phages tested yielded averages of 3.49 × 10(8) to 3.36 × 10(12) PFU/ml/day compared to averages of 1.28 × 10(5) to 1.30 × 10(10) PFU/ml/day by traditional methods. Host growth and death kinetics made this method ineffective for extended propagation of mesophilic phages. Crown Copyright © 2016. Published by Elsevier Masson SAS. All rights reserved.

  7. Reconstruction of electrical impedance tomography (EIT) images based on the expectation maximum (EM) method.

    PubMed

    Wang, Qi; Wang, Huaxiang; Cui, Ziqiang; Yang, Chengyi

    2012-11-01

    Electrical impedance tomography (EIT) calculates the internal conductivity distribution within a body using electrical contact measurements. The image reconstruction for EIT is an inverse problem, which is both non-linear and ill-posed. The traditional regularization method cannot avoid introducing negative values in the solution. The negativity of the solution produces artifacts in reconstructed images in presence of noise. A statistical method, namely, the expectation maximization (EM) method, is used to solve the inverse problem for EIT in this paper. The mathematical model of EIT is transformed to the non-negatively constrained likelihood minimization problem. The solution is obtained by the gradient projection-reduced Newton (GPRN) iteration method. This paper also discusses the strategies of choosing parameters. Simulation and experimental results indicate that the reconstructed images with higher quality can be obtained by the EM method, compared with the traditional Tikhonov and conjugate gradient (CG) methods, even with non-negative processing. Copyright © 2012 ISA. Published by Elsevier Ltd. All rights reserved.

  8. Developing indicators of pattern identification in patients with stroke using traditional Korean medicine

    PubMed Central

    2012-01-01

    Background The traditional Korean medical diagnoses employ pattern identification (PI), a diagnostic system that entails the comprehensive analysis of symptoms and signs. The PI needs to be standardized due to its ambiguity. Therefore, this study was performed to establish standard indicators of the PI for stroke through the traditional Korean medical literature, expert consensus and a clinical field test. Methods We sorted out stroke patterns with an expert committee organized by the Korean Institute of Oriental Medicine. The expert committee composed a document for a standardized pattern of identification for stroke based on the traditional Korean medical literature, and we evaluated the clinical significance of the document through a field test. Results We established five stroke patterns from the traditional Korean medical literature and extracted 117 indicators required for diagnosis. The indicators were evaluated by a field test and verified by the expert committee. Conclusions This study sought to develop indicators of PI based on the traditional Korean medical literature. This process contributed to the standardization of traditional Korean medical diagnoses. PMID:22410195

  9. The pedagogical toolbox: computer-generated visual displays, classroom demonstration, and lecture.

    PubMed

    Bockoven, Jerry

    2004-06-01

    This analogue study compared the effectiveness of computer-generated visual displays, classroom demonstration, and traditional lecture as methods of instruction used to teach neuronal structure and processes. Randomly assigned 116 undergraduate students participated in 1 of 3 classrooms in which they experienced the same content but different teaching approaches presented by 3 different student-instructors. Then participants completed a survey of their subjective reactions and a measure of factual information designed to evaluate objective learning outcomes. Participants repeated this factual measure 5 wk. later. Results call into question the use of classroom demonstration methods as well as the trend towards devaluing traditional lecture in favor of computer-generated visual display.

  10. New distributed activation energy model: numerical solution and application to pyrolysis kinetics of some types of biomass.

    PubMed

    Cai, Junmeng; Liu, Ronghou

    2008-05-01

    In the present paper, a new distributed activation energy model has been developed, considering the reaction order and the dependence of frequency factor on temperature. The proposed DAEM cannot be solved directly in a closed from, thus a method was used to obtain the numerical solution of the new DAEM equation. Two numerical examples to illustrate the proposed method were presented. The traditional DAEM and new DAEM have been used to simulate the pyrolytic process of some types of biomass. The new DAEM fitted the experimental data much better than the traditional DAEM as the dependence of the frequency factor on temperature was taken into account.

  11. [Exploration and practice of genetics teaching assisted by network technology platform].

    PubMed

    Li, Ya-Xuan; Zhang, Fei-Xiong; Zhao, Xin; Cai, Min-Hua; Yan, Yue-Ming; Hu, Ying-Kao

    2010-04-01

    More teaching techniques have been brought out gradually along with the development of new technologies. On the basis of those traditional teaching methods, a new platform has been set up by the network technology for teaching process. In genetics teaching, it is possible to use the network platform to guide student studying, promote student's learning interest and study independently by themselves. It has been proved, after exploring and applying for many years, that network teaching is one of the most useful methods and has inimitable advantage comparing to the traditional ones in genetics teaching. The establishment of network teaching platform, the advantage and deficiency and relevant strategies were intro-duced in this paper.

  12. [Study on arsenic speciation changes in crude and processed traditional Chinese medicines by HPLC-ICP-MS].

    PubMed

    Jin, Peng-fei; Wu, Xue-jun; Zou, Ding; Kuang, Yong-mei; Hu, Xin; Jiang, Wen-qing; Sun, Chun-hua

    2011-03-01

    A HPLC-ICP-MS method for simultaneous determination of As(III), As(V), MMA and DMA in traditional Chinese medicines (TCMs) was established, and the contents of As(III), As(V), MMA and DMA in a TCM with high total arsenic content (Cordyceps) and 5 crude and processed TCMs (Radix Astragali, Radix et Rhizoma Rhei, Radix Scutellariae, Radix Polygoni Multiflori and Radix Rehmanniae) were determined and analyzed. The method validation indicated that the correlative coefficients (r) for all speciations were bigger than 0.9984; the limits of quantitation (LOQ) were from 0.8 to 1.0 microg x L(-1); the reproducibility and stability were satisfactory with all RSDs less than 10%; the spiked recoveries ranged from 82.40% to 119.5%. The results of samples analysis showed that the inorganic arsenic (As(III) and As(V)) was the dominating speciation in the tested TCMs; MMA and DMA were not found in all plant resourced TCMs, but MMA was found in Cordyceps; all the tested TCMs indicated a content increasing of inorganic arsenic after processing.

  13. Automatic data-processing equipment of moon mark of nail for verifying some experiential theory of Traditional Chinese Medicine.

    PubMed

    Niu, Renjie; Fu, Chenyu; Xu, Zhiyong; Huang, Jianyuan

    2016-04-29

    Doctors who practice Traditional Chinese Medicine (TCM) diagnose using four methods - inspection, auscultation and olfaction, interrogation, and pulse feeling/palpation. The shape and shape changes of the moon marks on the nails are an important indication when judging the patient's health. There are a series of classical and experimental theories about moon marks in TCM, which does not have support from statistical data. To verify some experiential theories on moon mark in TCM by automatic data-processing equipment. This paper proposes the equipment that utilizes image processing technology to collect moon mark data of different target groups conveniently and quickly, building a database that combines this information with that gathered from the health and mental status questionnaire in each test. This equipment has a simple design, a low cost, and an optimized algorithm. The practice has been proven to quickly complete automatic acquisition and preservation of key data about moon marks. In the future, some conclusions will likely be obtained from these data; some changes of moon marks related to a special pathological change will be established with statistical methods.

  14. [Monitoring method of extraction process for Schisandrae Chinensis Fructus based on near infrared spectroscopy and multivariate statistical process control].

    PubMed

    Xu, Min; Zhang, Lei; Yue, Hong-Shui; Pang, Hong-Wei; Ye, Zheng-Liang; Ding, Li

    2017-10-01

    To establish an on-line monitoring method for extraction process of Schisandrae Chinensis Fructus, the formula medicinal material of Yiqi Fumai lyophilized injection by combining near infrared spectroscopy with multi-variable data analysis technology. The multivariate statistical process control (MSPC) model was established based on 5 normal batches in production and 2 test batches were monitored by PC scores, DModX and Hotelling T2 control charts. The results showed that MSPC model had a good monitoring ability for the extraction process. The application of the MSPC model to actual production process could effectively achieve on-line monitoring for extraction process of Schisandrae Chinensis Fructus, and can reflect the change of material properties in the production process in real time. This established process monitoring method could provide reference for the application of process analysis technology in the process quality control of traditional Chinese medicine injections. Copyright© by the Chinese Pharmaceutical Association.

  15. A method based on IHS cylindrical transform model for quality assessment of image fusion

    NASA Astrophysics Data System (ADS)

    Zhu, Xiaokun; Jia, Yonghong

    2005-10-01

    Image fusion technique has been widely applied to remote sensing image analysis and processing, and methods for quality assessment of image fusion in remote sensing have also become the research issues at home and abroad. Traditional assessment methods combine calculation of quantitative indexes and visual interpretation to compare fused images quantificationally and qualitatively. However, in the existing assessment methods, there are two defects: on one hand, most imdexes lack the theoretic support to compare different fusion methods. On the hand, there is not a uniform preference for most of the quantitative assessment indexes when they are applied to estimate the fusion effects. That is, the spatial resolution and spectral feature could not be analyzed synchronously by these indexes and there is not a general method to unify the spatial and spectral feature assessment. So in this paper, on the basis of the approximate general model of four traditional fusion methods, including Intensity Hue Saturation(IHS) triangle transform fusion, High Pass Filter(HPF) fusion, Principal Component Analysis(PCA) fusion, Wavelet Transform(WT) fusion, a correlation coefficient assessment method based on IHS cylindrical transform is proposed. By experiments, this method can not only get the evaluation results of spatial and spectral features on the basis of uniform preference, but also can acquire the comparison between fusion image sources and fused images, and acquire differences among fusion methods. Compared with the traditional assessment methods, the new methods is more intuitionistic, and in accord with subjective estimation.

  16. Assessment selection in human-automation interaction studies: The Failure-GAM2E and review of assessment methods for highly automated driving.

    PubMed

    Grane, Camilla

    2018-01-01

    Highly automated driving will change driver's behavioural patterns. Traditional methods used for assessing manual driving will only be applicable for the parts of human-automation interaction where the driver intervenes such as in hand-over and take-over situations. Therefore, driver behaviour assessment will need to adapt to the new driving scenarios. This paper aims at simplifying the process of selecting appropriate assessment methods. Thirty-five papers were reviewed to examine potential and relevant methods. The review showed that many studies still relies on traditional driving assessment methods. A new method, the Failure-GAM 2 E model, with purpose to aid assessment selection when planning a study, is proposed and exemplified in the paper. Failure-GAM 2 E includes a systematic step-by-step procedure defining the situation, failures (Failure), goals (G), actions (A), subjective methods (M), objective methods (M) and equipment (E). The use of Failure-GAM 2 E in a study example resulted in a well-reasoned assessment plan, a new way of measuring trust through feet movements and a proposed Optimal Risk Management Model. Failure-GAM 2 E and the Optimal Risk Management Model are believed to support the planning process for research studies in the field of human-automation interaction. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Ethnomathematics elements in Batik Bali using backpropagation method

    NASA Astrophysics Data System (ADS)

    Lestari, Mei; Irawan, Ari; Rahayu, Wanti; Wayan Parwati, Ni

    2018-05-01

    Batik is one of traditional arts that has been established by the UNESCO as Indonesia’s cultural heritage. Batik has varieties and motifs, and each motifs has its own uniqueness but seems similar, that makes it difficult to identify. This study aims to develop an application that can identify typical batik Bali with etnomatematics elements on it. Etnomatematics is a study that shows relation between culture and mathematics concepts. Etnomatematics in Batik Bali is more to geometrical concept in line of strong Balinese culture element. The identification process is use backpropagation method. Steps of backpropagation methods are image processing (including scalling and tresholding image process). Next step is insert the processed image to an artificial neural network. This study resulted an accuracy of identification of batik Bali that has Etnomatematics elements on it.

  18. Plasma technologies application for building materials surface modification

    NASA Astrophysics Data System (ADS)

    Volokitin, G. G.; Skripnikova, N. K.; Volokitin, O. G.; Shehovtzov, V. V.; Luchkin, A. G.; Kashapov, N. F.

    2016-01-01

    Low temperature arc plasma was used to process building surface materials, such as silicate brick, sand lime brick, concrete and wood. It was shown that building surface materials modification with low temperature plasma positively affects frost resistance, water permeability and chemical resistance with high adhesion strength. Short time plasma processing is rather economical than traditional processing thermic methods. Plasma processing makes wood surface uniquely waterproof and gives high operational properties, dimensional and geometrical stability. It also increases compression resistance and decreases inner tensions level in material.

  19. System identification of a small low-cost unmanned aerial vehicle using flight data from low-cost sensors

    NASA Astrophysics Data System (ADS)

    Hoffer, Nathan Von

    Remote sensing has traditionally been done with satellites and manned aircraft. While. these methods can yield useful scientificc data, satellites and manned aircraft have limitations in data frequency, process time, and real time re-tasking. Small low-cost unmanned aerial vehicles (UAVs) provide greater possibilities for personal scientic research than traditional remote sensing platforms. Precision aerial data requires an accurate vehicle dynamics model for controller development, robust flight characteristics, and fault tolerance. One method of developing a model is system identification (system ID). In this thesis system ID of a small low-cost fixed-wing T-tail UAV is conducted. The linerized longitudinal equations of motion are derived from first principles. Foundations of Recursive Least Squares (RLS) are presented along with RLS with an Error Filtering Online Learning scheme (EFOL). Sensors, data collection, data consistency checking, and data processing are described. Batch least squares (BLS) and BLS with EFOL are used to identify aerodynamic coecoefficients of the UAV. Results of these two methods with flight data are discussed.

  20. A Roadmap for Using Agile Development in a Traditional Environment

    NASA Technical Reports Server (NTRS)

    Streiffert, Barbara; Starbird, Thomas; Grenander, Sven

    2006-01-01

    One of the newer classes of software engineering techniques is called 'Agile Development'. In Agile Development software engineers take small implementation steps and, in some cases, they program in pairs. In addition, they develop automatic tests prior to implementing their small functional piece. Agile Development focuses on rapid turnaround, incremental planning, customer involvement and continuous integration. Agile Development is not the traditional waterfall method or even a rapid prototyping method (although this methodology is closer to Agile Development). At the Jet Propulsion Laboratory (JPL) a few groups have begun Agile Development software implementations. The difficulty with this approach becomes apparent when Agile Development is used in an organization that has specific criteria and requirements handed down for how software development is to be performed. The work at the JPL is performed for the National Aeronautics and Space Agency (NASA). Both organizations have specific requirements, rules and processes for developing software. This paper will discuss some of the initial uses of the Agile Development methodology, the spread of this method and the current status of the successful incorporation into the current JPL development policies and processes.

  1. Hybrid sentiment analysis utilizing multiple indicators to determine temporal shifts of opinion in OSNs

    NASA Astrophysics Data System (ADS)

    White, Joshua S.; Hall, Robert T.; Fields, Jeremy; White, Holly M.

    2016-05-01

    Utilization of traditional sentiment analysis for predicting the outcome of an event on a social network depends on: precise understanding of what topics relate to the event, selective elimination of trends that don't fit, and in most cases, expert knowledge of major players of the event. Sentiment analysis has traditionally taken one of two approaches to derive a quantitative value from qualitative text. These approaches include the bag of words model", and the usage of "NLP" to attempt a real understanding of the text. Each of these methods yield very similar accuracy results with the exception of some special use cases. To do so, however, they both impose a large computational burden on the analytic system. Newer approaches have this same problem. No matter what approach is used, SA typically caps out around 80% in accuracy. However, accuracy is the result of both polarity and degree of polarity, nothing else. In this paper we present a method for hybridizing traditional SA methods to better determine shifts in opinion over time within social networks. This hybridization process involves augmenting traditional SA measurements with contextual understanding, and knowledge about writers' demographics. Our goal is to not only to improve accuracy, but to do so with minimal impact to computation requirements.

  2. [An improved algorithm for electrohysterogram envelope extraction].

    PubMed

    Lu, Yaosheng; Pan, Jie; Chen, Zhaoxia; Chen, Zhaoxia

    2017-02-01

    Extraction uterine contraction signal from abdominal uterine electromyogram(EMG) signal is considered as the most promising method to replace the traditional tocodynamometer(TOCO) for detecting uterine contractions activity. The traditional root mean square(RMS) algorithm has only some limited values in canceling the impulsive noise. In our study, an improved algorithm for uterine EMG envelope extraction was proposed to overcome the problem. Firstly, in our experiment, zero-crossing detection method was used to separate the burst of uterine electrical activity from the raw uterine EMG signal. After processing the separated signals by employing two filtering windows which have different width, we used the traditional RMS algorithm to extract uterus EMG envelope. To assess the performance of the algorithm, the improved algorithm was compared with two existing intensity of uterine electromyogram(IEMG) extraction algorithms. The results showed that the improved algorithm was better than the traditional ones in eliminating impulsive noise present in the uterine EMG signal. The measurement sensitivity and positive predictive value(PPV) of the improved algorithm were 0.952 and 0.922, respectively, which were not only significantly higher than the corresponding values(0.859 and 0.847) of the first comparison algorithm, but also higher than the values(0.928 and 0.877) of the second comparison algorithm. Thus the new method is reliable and effective.

  3. Mobile Laser Scanning for Indoor Modelling

    NASA Astrophysics Data System (ADS)

    Thomson, C.; Apostolopoulos, G.; Backes, D.; Boehm, J.

    2013-10-01

    The process of capturing and modelling buildings has gained increased focus in recent years with the rise of Building Information Modelling (BIM). At the heart of BIM is a process change for the construction and facilities management industries whereby a BIM aids more collaborative working through better information exchange, and as a part of the process Geomatic/Land Surveyors are not immune from the changes. Terrestrial laser scanning has been proscribed as the preferred method for rapidly capturing buildings for BIM geometry. This is a process change from a traditional measured building survey just with a total station and is aided by the increasing acceptance of point cloud data being integrated with parametric building models in BIM tools such as Autodesk Revit or Bentley Architecture. Pilot projects carried out previously by the authors to investigate the geometry capture and modelling of BIM confirmed the view of others that the process of data capture with static laser scan setups is slow and very involved requiring at least two people for efficiency. Indoor Mobile Mapping Systems (IMMS) present a possible solution to these issues especially in time saved. Therefore this paper investigates their application as a capture device for BIM geometry creation over traditional static methods through a fit-for-purpose test.

  4. A Portable Dynamic Laser Speckle System for Sensing Long-Term Changes Caused by Treatments in Painting Conservation

    PubMed Central

    Pérez, Alberto J.; Braga, Roberto; Perles, Ángel; Pérez–Marín, Eva; García-Diego, Fernando J.

    2018-01-01

    Dynamic laser speckle (DLS) is used as a reliable sensor of activity for all types of materials. Traditional applications are based on high-rate captures (usually greater than 10 frames-per-second, fps). Even for drying processes in conservation treatments, where there is a high level of activity in the first moments after the application and slower activity after some minutes or hours, the process is based on the acquisition of images at a time rate that is the same in moments of high and low activity. In this work, we present an alternative approach to track the drying process of protective layers and other painting conservation processes that take a long time to reduce their levels of activity. We illuminate, using three different wavelength lasers, a temporary protector (cyclododecane) and a varnish, and monitor them using a low fps rate during long-term drying. The results are compared to the traditional method. This work also presents a monitoring method that uses portable equipment. The results present the feasibility of using the portable device and show the improved sensitivity of the dynamic laser speckle when sensing the long-term process for drying cyclododecane and varnish in conservation. PMID:29324692

  5. Chemical Compounds and Extraction Methods of "Maollahm".

    PubMed

    Sadeghpoor, Omid; Dayeni, Manijeh; Razi, Samane

    2016-05-01

    Maollahm or meat juice, a by-product of meat, is a traditional remedy in Persian medicine. This product was used as a nourishment or treatment substance for sick people. According to the ancient Persian medicine, animal meat has more affinity with the human body and the body easily absorbs its nutrition. Therefore, one could resort to maollahm for patients requiring urgent nourishment to boost and strengthen their body. In this work, different ways of preparing maollahm from poultry, goat, cow, and sheep meat are studied. Most of these methods are based on distillation or barbecue before distillation, as prescribed by traditional medicine books. The reactions, chemical processes, and volatile compounds related to different types of cooked meat are also compared with the outcome of recent research studies. The difference between various types of meat is related to their compounds. Different cooking processes such as barbecuing, roasting, cooking, and boiling have an effect on the taste, smell and the chemical constituents of maollahm. Additionally, the type of meat, animal feed, as well as using or removing the fat during the cooking process, have an effect on the produced volatile compounds. Cooking process and the type of meat have a direct effect on the compounds of maollahm. Possible reactions in the preparation process of maollahm are investigated and presented according to the new research studies.

  6. Assessing and evaluating multidisciplinary translational teams: a mixed methods approach.

    PubMed

    Wooten, Kevin C; Rose, Robert M; Ostir, Glenn V; Calhoun, William J; Ameredes, Bill T; Brasier, Allan R

    2014-03-01

    A case report illustrates how multidisciplinary translational teams can be assessed using outcome, process, and developmental types of evaluation using a mixed-methods approach. Types of evaluation appropriate for teams are considered in relation to relevant research questions and assessment methods. Logic models are applied to scientific projects and team development to inform choices between methods within a mixed-methods design. Use of an expert panel is reviewed, culminating in consensus ratings of 11 multidisciplinary teams and a final evaluation within a team-type taxonomy. Based on team maturation and scientific progress, teams were designated as (a) early in development, (b) traditional, (c) process focused, or (d) exemplary. Lessons learned from data reduction, use of mixed methods, and use of expert panels are explored.

  7. Studies on Tasar Cocoon Cooking Using Permeation Method

    NASA Astrophysics Data System (ADS)

    Javali, Uday C.; Malali, Kiran B.; Ramya, H. G.; Naik, Subhas V.; Padaki, Naveen V.

    2018-02-01

    Cocoon cooking is an important process before reeling of tasar silk yarn. Cooking ensures loosening of the filaments in the tasar cocoons thereby easing the process of yarn withdrawal during reeling process. Tasar cocoons have very hard shell and hence these cocoons need chemical cooking process to loosen the silk filaments. Attempt has been made in this article to study the effect of using vacuum permeation chamber for tasar cocoon cooking in order to reduce the cooking time and improve the quality of tasar silk yarn. Vacuum assisted permeation cooking method has been studied in this article on tasar daba cocoons for cooking efficiency, deflossing and reelability. Its efficiency has been evaluated with respect to different cooking methods viz, traditional and open pan cooking methods. The tasar silk produced after reeling process has been tested for fineness, strength and cohesion properties. Results indicate that permeation method of tasar cooking ensures uniform cooking with higher efficiency along with better reeling performance and improved yarn properties.

  8. Application of 3d Model of Cultural Relics in Virtual Restoration

    NASA Astrophysics Data System (ADS)

    Zhao, S.; Hou, M.; Hu, Y.; Zhao, Q.

    2018-04-01

    In the traditional cultural relics splicing process, in order to identify the correct spatial location of the cultural relics debris, experts need to manually splice the existing debris. The repeated contact between debris can easily cause secondary damage to the cultural relics. In this paper, the application process of 3D model of cultural relic in virtual restoration is put forward, and the relevant processes and ideas are verified with the example of Terracotta Warriors data. Through the combination of traditional cultural relics restoration methods and computer virtual reality technology, virtual restoration of high-precision 3D models of cultural relics can provide a scientific reference for virtual restoration, avoiding the secondary damage to the cultural relics caused by improper restoration. The efficiency and safety of the preservation and restoration of cultural relics have been improved.

  9. [Application progress on near infrared spectroscopy in quality control and process monitoring of traditional Chinese medicine].

    PubMed

    Li, Wenlong; Qu, Haibin

    2017-01-25

    The industry of traditional Chinese medicine (TCM) encounters problems like quality fluctuation of raw materials and unstandardized production process. Near infrared (NIR) spectroscopy technology is widely used in quality control of TCM because of its abundant information, fast and nondestructive characters. The main applications include quantitative analysis of Chinese medicinal materials, intermediates and Chinese patent medicines; the authenticity of TCM, species, origins and manufacturers; monitoring and control of the extraction, alcohol precipitation, column chromatography and blending process. This article reviews the progress on the application of NIR spectroscopy technology in TCM field. In view of the problems existing in the application, the article proposes that the standardization of NIR analysis method should be developed according to specific characteristics of TCM, which will promote the application of NIR technology in the TCM industry.

  10. High-throughput process development: determination of dynamic binding capacity using microtiter filter plates filled with chromatography resin.

    PubMed

    Bergander, Tryggve; Nilsson-Välimaa, Kristina; Oberg, Katarina; Lacki, Karol M

    2008-01-01

    Steadily increasing demand for more efficient and more affordable biomolecule-based therapies put a significant burden on biopharma companies to reduce the cost of R&D activities associated with introduction of a new drug to the market. Reducing the time required to develop a purification process would be one option to address the high cost issue. The reduction in time can be accomplished if more efficient methods/tools are available for process development work, including high-throughput techniques. This paper addresses the transitions from traditional column-based process development to a modern high-throughput approach utilizing microtiter filter plates filled with a well-defined volume of chromatography resin. The approach is based on implementing the well-known batch uptake principle into microtiter plate geometry. Two variants of the proposed approach, allowing for either qualitative or quantitative estimation of dynamic binding capacity as a function of residence time, are described. Examples of quantitative estimation of dynamic binding capacities of human polyclonal IgG on MabSelect SuRe and of qualitative estimation of dynamic binding capacity of amyloglucosidase on a prototype of Capto DEAE weak ion exchanger are given. The proposed high-throughput method for determination of dynamic binding capacity significantly reduces time and sample consumption as compared to a traditional method utilizing packed chromatography columns without sacrificing the accuracy of data obtained.

  11. Automated system for definition of life-cycle resources of electromechanical equipment

    NASA Astrophysics Data System (ADS)

    Zhukovskiy, Y.; Koteleva, N.

    2017-02-01

    The frequency of maintenance of electromechanical equipment depends on the plant, which uses and runs this equipment. Very often the maintenance frequency is poorly correlated with the actual state of the electromechanical equipment. Furthermore, traditional methods of diagnosis sometimes cannot work without stopping the process (for example, for equipment located in hard to reach places) and so the maintenance costs are increased. This problem can be solved using the indirect methods of diagnosing of the electromechanical equipment. The indirect methods often use the parameters in the real time and seldom use the parameters of traditional diagnostic methods for determination of the resource of electromechanical equipment. This article is dedicated to developing the structure of a special automated control system. This system must use the big flow of the information about the direct and indirect parameters of the equipment state from plants from different areas of industry and factories which produce the electromechanical equipment.

  12. Ultrasound image edge detection based on a novel multiplicative gradient and Canny operator.

    PubMed

    Zheng, Yinfei; Zhou, Yali; Zhou, Hao; Gong, Xiaohong

    2015-07-01

    To achieve the fast and accurate segmentation of ultrasound image, a novel edge detection method for speckle noised ultrasound images was proposed, which was based on the traditional Canny and a novel multiplicative gradient operator. The proposed technique combines a new multiplicative gradient operator of non-Newtonian type with the traditional Canny operator to generate the initial edge map, which is subsequently optimized by the following edge tracing step. To verify the proposed method, we compared it with several other edge detection methods that had good robustness to noise, with experiments on the simulated and in vivo medical ultrasound image. Experimental results showed that the proposed algorithm has higher speed for real-time processing, and the edge detection accuracy could be 75% or more. Thus, the proposed method is very suitable for fast and accurate edge detection of medical ultrasound images. © The Author(s) 2014.

  13. The commercialization of traditional medicine in modern Cambodia.

    PubMed

    Ros, Bandeth; Lê, Gillian; McPake, Barbara; Fustukian, Suzanne

    2018-01-01

    Globally, traditional medicine has long been used to address relatively common illness, mental ill health and during childbirth and post-natal care. However, traditional medicine is primarily provided by the private sector and it is unclear how far expenditures on traditional medicine contribute to household impoverishment. A life history method was used to understand the health seeking experience of 24 households over the last 60 years in Cambodia, a country with high out-of-pocket expenditures for health. The life histories suggest that traditional medicine in Cambodia has been undergoing a process of commercialization, with significant impacts on poor households. In the earlier lives of respondents, payments for traditional medicine were reported to have been flexible, voluntary or appropriate to patients' financial means. In contrast, contemporary practitioners appear to seek immediate cash payments that have frequently led to considerable debt and asset sales by traditional medicine users. Given traditional medicine's popularity as a source of treatment in Cambodia and its potential to contribute to household impoverishment, we suggest that it needs to be included in a national conversation about achieving Universal Health Coverage in the country. © The Author 2017. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine.

  14. [Ideas and methods on efficient screening of traditional medicines for anti-osteoporosis activity based on M-Act/Tox integrated evaluation using zebrafish].

    PubMed

    Wang, Mo; Ling, Jie; Chen, Ying; Song, Jie; Sun, E; Shi, Zi-Qi; Feng, Liang; Jia, Xiao-Bin; Wei, Ying-Jie

    2017-11-01

    The increasingly apparent liver injury problems of bone strengthening Chinese medicines have brought challenges for clinical application, and it is necessary to consider both effectiveness and safety in screening anti-osteoporosis Chinese medicines. Metabolic transformation is closely related to drug efficacy and toxicity, so it is significant to comprehensively consider metabolism-action/toxicity(M-Act/Tox) for screening anti-osteoporosis Chinese medicines. The current evaluation models and the number of compounds(including metabolites) severely restrict efficient screening in vivo. By referring to previous relevant research and domestic and abroad literature, zebrafish M-Act/Tox integrative method was put forward for efficiently screening anti-osteoporosis herb medicines, which has organically integrated zebrafish metabolism model, osteoporosis model and toxicity evaluation method. This method can break through the bottleneck and blind spots that trace compositions can't achieve efficient and integrated in vivo evaluation, and realize both efficient and comprehensive screening on anti-osteoporosis traditional medicines based on in vivo process taking both safety and effectiveness into account, which is significant to accelerate discovery of effective and safe innovative traditional Chinese medicines for osteoporosis. Copyright© by the Chinese Pharmaceutical Association.

  15. Study on light weight design of truss structures of spacecrafts

    NASA Astrophysics Data System (ADS)

    Zeng, Fuming; Yang, Jianzhong; Wang, Jian

    2015-08-01

    Truss structure is usually adopted as the main structure form for spacecrafts due to its high efficiency in supporting concentrated loads. Light-weight design is now becoming the primary concern during conceptual design of spacecrafts. Implementation of light-weight design on truss structure always goes through three processes: topology optimization, size optimization and composites optimization. During each optimization process, appropriate algorithm such as the traditional optimality criterion method, mathematical programming method and the intelligent algorithms which simulate the growth and evolution processes in nature will be selected. According to the practical processes and algorithms, combined with engineering practice and commercial software, summary is made for the implementation of light-weight design on truss structure for spacecrafts.

  16. Information Technology and Academic Productivity.

    ERIC Educational Resources Information Center

    Massy, William F.; Zemsky, Robert

    1996-01-01

    Enumerates the challenges of adopting information technology (IT)-based teaching and learning strategies in higher education. Concerns addressed include whether IT should supplant rather than augment traditional teaching methods, the financing of IT acquisition, change of teaching and learning processes to increase productivity per person, and…

  17. QUANTIFYING SPATIAL POSITION OF WETLANDS FOR STREAM HABITAT QUALITY PREDICTION

    EPA Science Inventory

    A watershed's capacity to store and filter water, and the resulting effects on the hydrologic regine, is a key forcing function for insteam processes and community structure. However, methods for describing wetland position have traditionally been qualitative. A Geographic Info...

  18. Determination of Carbonyl Functional Groups in Bio-oils by Potentiometric Titration: The Faix Method.

    PubMed

    Black, Stuart; Ferrell, Jack R

    2017-02-07

    Carbonyl compounds present in bio-oils are known to be responsible for bio-oil property changes upon storage and during upgrading. Specifically, carbonyls cause an increase in viscosity (often referred to as 'aging') during storage of bio-oils. As such, carbonyl content has previously been used as a method of tracking bio-oil aging and condensation reactions with less variability than viscosity measurements. Additionally, carbonyls are also responsible for coke formation in bio-oil upgrading processes. Given the importance of carbonyls in bio-oils, accurate analytical methods for their quantification are very important for the bio-oil community. Potentiometric titration methods based on carbonyl oximation have long been used for the determination of carbonyl content in pyrolysis bio-oils. Here, we present a modification of the traditional carbonyl oximation procedures that results in less reaction time, smaller sample size, higher precision, and more accurate carbonyl determinations. While traditional carbonyl oximation methods occur at room temperature, the Faix method presented here occurs at an elevated temperature of 80 °C.

  19. Multivariate fault isolation of batch processes via variable selection in partial least squares discriminant analysis.

    PubMed

    Yan, Zhengbing; Kuang, Te-Hui; Yao, Yuan

    2017-09-01

    In recent years, multivariate statistical monitoring of batch processes has become a popular research topic, wherein multivariate fault isolation is an important step aiming at the identification of the faulty variables contributing most to the detected process abnormality. Although contribution plots have been commonly used in statistical fault isolation, such methods suffer from the smearing effect between correlated variables. In particular, in batch process monitoring, the high autocorrelations and cross-correlations that exist in variable trajectories make the smearing effect unavoidable. To address such a problem, a variable selection-based fault isolation method is proposed in this research, which transforms the fault isolation problem into a variable selection problem in partial least squares discriminant analysis and solves it by calculating a sparse partial least squares model. As different from the traditional methods, the proposed method emphasizes the relative importance of each process variable. Such information may help process engineers in conducting root-cause diagnosis. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

  20. Weaving a Formal Methods Education with Problem-Based Learning

    NASA Astrophysics Data System (ADS)

    Gibson, J. Paul

    The idea of weaving formal methods through computing (or software engineering) degrees is not a new one. However, there has been little success in developing and implementing such a curriculum. Formal methods continue to be taught as stand-alone modules and students, in general, fail to see how fundamental these methods are to the engineering of software. A major problem is one of motivation — how can the students be expected to enthusiastically embrace a challenging subject when the learning benefits, beyond passing an exam and achieving curriculum credits, are not clear? Problem-based learning has gradually moved from being an innovative pedagogique technique, commonly used to better-motivate students, to being widely adopted in the teaching of many different disciplines, including computer science and software engineering. Our experience shows that a good problem can be re-used throughout a student's academic life. In fact, the best computing problems can be used with children (young and old), undergraduates and postgraduates. In this paper we present a process for weaving formal methods through a University curriculum that is founded on the application of problem-based learning and a library of good software engineering problems, where students learn about formal methods without sitting a traditional formal methods module. The process of constructing good problems and integrating them into the curriculum is shown to be analagous to the process of engineering software. This approach is not intended to replace more traditional formal methods modules: it will better prepare students for such specialised modules and ensure that all students have an understanding and appreciation for formal methods even if they do not go on to specialise in them.

  1. Remote sensing of coal mine pollution in the upper Potomac River basin

    NASA Technical Reports Server (NTRS)

    1974-01-01

    A survey of remote sensing data pertinent to locating and monitoring sources of pollution resulting from surface and shaft mining operations was conducted in order to determine the various methods by which ERTS and aircraft remote sensing data can be used as a replacement for, or a supplement to traditional methods of monitoring coal mine pollution of the upper Potomac Basin. The gathering and analysis of representative samples of the raw and processed data obtained during the survey are described, along with plans to demonstrate and optimize the data collection processes.

  2. Interpretation of interference signals in label free integrated interferometric biosensors

    NASA Astrophysics Data System (ADS)

    Heikkinen, Hanna; Wang, Meng; Okkonen, Matti; Hast, Jukka; Myllylä, Risto

    2006-02-01

    In the future fast, simple and reliable biosensors will be needed to detect various analytes from different biosamples. This is due to fact that the needs of traditional health care are changing. In the future homecare of patients and peoples' responsibility for their own health will increase. Also, different wellness applications need new parameters to be analysed, reducing costs of traditional health care, which are increasing rapidly. One fascinating and promising sensor type for these applications is an integrated optical interferometric immunosensor, which is manufactured using organic materials. The use of organic materials opens up enormous possibilities to develop different biochemical functions. In label free biosensors the measurement is based on detecting changes in refractive index, which typically are in the range of 10 -6-10 -8 [1]. In this research, theoretically generated interferograms are used to compare various signal processing methods. The goal is to develop an efficient method to analyse the interferogram. Different time domain signal processing methods are studied to determine the measuring resolution and efficiency of these methods. A low cost CCD -element is used in detecting the interferogram dynamics. It was found that in most of the signal processing methods the measuring resolution was mainly limited by pixel size. With calculation of Pearson's correlation coefficient, subpixel resolution was achieved which means that nanometer range optical path differences can be measured. This results in the refractive index resolution of the order of 10 -7.

  3. Comparison of Satellite Surveying to Traditional Surveying Methods for the Resources Industry

    NASA Astrophysics Data System (ADS)

    Osborne, B. P.; Osborne, V. J.; Kruger, M. L.

    Modern ground-based survey methods involve detailed survey, which provides three-space co-ordinates for surveyed points, to a high level of accuracy. The instruments are operated by surveyors, who process the raw results to create survey location maps for the subject of the survey. Such surveys are conducted for a location or region and referenced to the earth global co- ordinate system with global positioning system (GPS) positioning. Due to this referencing the survey is only as accurate as the GPS reference system. Satellite survey remote sensing utilise satellite imagery which have been processed using commercial geographic information system software. Three-space co-ordinate maps are generated, with an accuracy determined by the datum position accuracy and optical resolution of the satellite platform.This paper presents a case study, which compares topographic surveying undertaken by traditional survey methods with satellite surveying, for the same location. The purpose of this study is to assess the viability of satellite remote sensing for surveying in the resources industry. The case study involves a topographic survey of a dune field for a prospective mining project area in Pakistan. This site has been surveyed using modern surveying techniques and the results are compared to a satellite survey performed on the same area.Analysis of the results from traditional survey and from the satellite survey involved a comparison of the derived spatial co- ordinates from each method. In addition, comparisons have been made of costs and turnaround time for both methods.The results of this application of remote sensing is of particular interest for survey in areas with remote and extreme environments, weather extremes, political unrest, poor travel links, which are commonly associated with mining projects. Such areas frequently suffer language barriers, poor onsite technical support and resources.

  4. Review: magnetically assisted resistance spot welding

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Y. B.; Li, D. L.; Lin, Z. Q.

    2016-02-25

    Currently, the use of advanced high strength steels (AHSSs) is the most cost effective means of reducing vehicle body weight and maintaining structural integrity at the same time. However, AHSSs present a big challenge to the traditional resistance spot welding (RSW) widely applied in automotive industries because the rapid heating and cooling procedures during RSW produce hardened weld microstructures, which lower the ductility and fatigue properties of welded joints and raise the probability of interfacial failure under external loads. Changing process parameters or post-weld heat treatment may reduce the weld brittleness, but those traditional quality control methods also increase energymore » consumption and prolong cycle time. In recent years, a magnetically assisted RSW (MA-RSW) method was proposed, in which an externally applied magnetic field would interact with the conduction current to produce a Lorentz force that would affect weld nugget formation. This paper is a review of an experimental MA-RSW platform, the mode of the external magnetic field and the mechanism that controls nugget shape, weld microstructures and joint performance. In conclusion, the advantages of the MA-RSW method in improving the weldability of AHSSs are given, a recent application of the MA-RSW process to light metals is described and the outlook for the MA-RSW process is presented.« less

  5. Photonic crystal beads from gravity-driven microfluidics.

    PubMed

    Gu, Hongcheng; Rong, Fei; Tang, Baocheng; Zhao, Yuanjin; Fu, Degang; Gu, Zhongze

    2013-06-25

    This Letter reports a simple method for the mass production of 3D colloidal photonic crystal beads (PCBs) by using a gravity-driven microfluidic device and online droplet drying method. Compared to traditional methods, the droplet templates of the PCBs are generated by using the ultrastable gravity as the driving force for the microfluidics, thus the PCBs are formed with minimal polydispersity. Moreover, drying of the droplet templates is integrated into the production process, and the nanoparticles in the droplets self-assemble online. Overall, this process results in PCBs with good morphology, low polydispersity, brilliant structural colors, and narrow stop bands. PCBs could be bulk generated by this process for many practical applications, such as multiplex-encoded assays and the construction of novel optical materials.

  6. Evaluation Measures and Methods: Some Intersections.

    ERIC Educational Resources Information Center

    Elliott, John

    The literature is reviewed for four combinations of evaluation measures and methods: traditional methods with traditional measures (T-Meth/T-Mea), nontraditional methods with traditional measures (N-Meth/T-Mea), traditional measures with nontraditional measures (T-Meth/N-Mea), and nontraditional methods with nontraditional measures (N-Meth/N-Mea).…

  7. Chemical profiling in Moutan Cortex after sulfuring and desulfuring processes reveals further insights into the quality control of TCMs by nontargeted metabolomic analysis.

    PubMed

    Zhan, Zhi-Lai; Deng, Ai-Ping; Kang, Li-Ping; Tang, Jin-Fu; Nan, Tie-Gui; Chen, Tong; He, Ya-Li; Guo, Lan-Ping; Huang, Lu-Qi

    2018-05-01

    As a traditional processing method, sulfuring has been used in the processing of many traditional Chinese medicines (TCMs). Desulfuring, which has emerged in recent years, is a new method applied to sulfured herbs so they can comply with regulations regarding residual SO 2 . Due to the chemical transformations and the residual SO 2 in the herbs, both sulfuring and desulfuring have negative effects on the safety and therapeutic effects of TCMs, and Moutan Cortex is one of the TCMs most susceptible to these effects. Here, a new strategy was developed to differentiate normal, sulfured and desulfured Moutan Cortex, and the transformations of compounds in sulfuring and desulfuring processes were analyzed using ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC/Q-TOF-MSE) method based on metabolomic analysis. Our findings were as follows: (1) a total of 119 compounds were identified or tentatively identified, including 9 compounds that are being reported for the first time as natural products; (2) 15 sulfocompounds were generated during the sulfuring process; (3) these sulfocompounds could not be converted back into their corresponding glycosides by the desulfuring process, and the desulfuring decreased the residual SO 2 ,while also removing some soluble compounds in the sulfured Moutan Cortex; and (4) 28 compounds were screened and tentatively identified as markers for distinguishing normal, sulfured and desulfured Moutan Cortex. Our findings provide a new practical strategy for evaluating how sulfuring and desulfuring affect the quality of TCMs. Copyright © 2018 Elsevier B.V. All rights reserved.

  8. Brightness checkerboard lattice method for the calibration of the coaxial reverse Hartmann test

    NASA Astrophysics Data System (ADS)

    Li, Xinji; Hui, Mei; Li, Ning; Hu, Shinan; Liu, Ming; Kong, Lingqin; Dong, Liquan; Zhao, Yuejin

    2018-01-01

    The coaxial reverse Hartmann test (RHT) is widely used in the measurement of large aspheric surfaces as an auxiliary method for interference measurement, because of its large dynamic range, highly flexible test with low frequency of surface errors, and low cost. And the accuracy of the coaxial RHT depends on the calibration. However, the calibration process remains inefficient, and the signal-to-noise ratio limits the accuracy of the calibration. In this paper, brightness checkerboard lattices were used to replace the traditional dot matrix. The brightness checkerboard method can reduce the number of dot matrix projections in the calibration process, thus improving efficiency. An LCD screen displayed a brightness checkerboard lattice, in which the brighter checkerboard and the darker checkerboard alternately arranged. Based on the image on the detector, the relationship between the rays at certain angles and the photosensitive positions of the detector coordinates can be obtained. And a differential de-noising method can effectively reduce the impact of noise on the measurement results. Simulation and experimentation proved the feasibility of the method. Theoretical analysis and experimental results show that the efficiency of the brightness checkerboard lattices is about four times that of the traditional dot matrix, and the signal-to-noise ratio of the calibration is significantly improved.

  9. Research on key technologies of data processing in internet of things

    NASA Astrophysics Data System (ADS)

    Zhu, Yangqing; Liang, Peiying

    2017-08-01

    The data of Internet of things (IOT) has the characteristics of polymorphism, heterogeneous, large amount and processing real-time. The traditional structured and static batch processing method has not met the requirements of data processing of IOT. This paper studied a middleware that can integrate heterogeneous data of IOT, and integrated different data formats into a unified format. Designed a data processing model of IOT based on the Storm flow calculation architecture, integrated the existing Internet security technology to build the Internet security system of IOT data processing, which provided reference for the efficient transmission and processing of IOT data.

  10. A mathematical method for precisely calculating the radiographic angles of the cup after total hip arthroplasty.

    PubMed

    Zhao, Jing-Xin; Su, Xiu-Yun; Xiao, Ruo-Xiu; Zhao, Zhe; Zhang, Li-Hai; Zhang, Li-Cheng; Tang, Pei-Fu

    2016-11-01

    We established a mathematical method to precisely calculate the radiographic anteversion (RA) and radiographic inclination (RI) angles of the acetabular cup based on anterior-posterior (AP) pelvic radiographs after total hip arthroplasty. Using Mathematica software, a mathematical model for an oblique cone was established to simulate how AP pelvic radiographs are obtained and to address the relationship between the two-dimensional and three-dimensional geometry of the opening circle of the cup. In this model, the vertex was the X-ray beam source, and the generatrix was the ellipse in radiographs projected from the opening circle of the acetabular cup. Using this model, we established a series of mathematical formulas to reveal the differences between the true RA and RI cup angles and the measurements results achieved using traditional methods and AP pelvic radiographs and to precisely calculate the RA and RI cup angles based on post-operative AP pelvic radiographs. Statistical analysis indicated that traditional methods should be used with caution if traditional measurements methods are used to calculate the RA and RI cup angles with AP pelvic radiograph. The entire calculation process could be performed by an orthopedic surgeon with mathematical knowledge of basic matrix and vector equations. Copyright © 2016 IPEM. Published by Elsevier Ltd. All rights reserved.

  11. Ontology method for 3DGIS modeling

    NASA Astrophysics Data System (ADS)

    Sun, Min; Chen, Jun

    2006-10-01

    Data modeling is a baffling problem in 3DGIS, no satisfied solution has been provided until today, reason come from various sides. In this paper, a new solution named "Ontology method" is proposed. GIS traditional modeling method mainly focus on geometrical modeling, i.e., try to abstract geometry primitives for objects representation, this kind modeling method show it's awkward in 3DGIS modeling process. Ontology method begins modeling from establishing a set of ontology with different levels. The essential difference of this method is to swap the position of 'spatial data' and 'attribute data' in 2DGIS modeling process for 3DGIS modeling. Ontology method has great advantages in many sides, a system based on ontology is easy to realize interoperation for communication and data mining for knowledge deduction, in addition has many other advantages.

  12. Analysis of mixed model in gear transmission based on ADAMS

    NASA Astrophysics Data System (ADS)

    Li, Xiufeng; Wang, Yabin

    2012-09-01

    The traditional method of mechanical gear driving simulation includes gear pair method and solid to solid contact method. The former has higher solving efficiency but lower results accuracy; the latter usually obtains higher precision of results while the calculation process is complex, also it is not easy to converge. Currently, most of the researches are focused on the description of geometric models and the definition of boundary conditions. However, none of them can solve the problems fundamentally. To improve the simulation efficiency while ensure the results with high accuracy, a mixed model method which uses gear tooth profiles to take the place of the solid gear to simulate gear movement is presented under these circumstances. In the process of modeling, build the solid models of the mechanism in the SolidWorks firstly; Then collect the point coordinates of outline curves of the gear using SolidWorks API and create fit curves in Adams based on the point coordinates; Next, adjust the position of those fitting curves according to the position of the contact area; Finally, define the loading conditions, boundary conditions and simulation parameters. The method provides gear shape information by tooth profile curves; simulates the mesh process through tooth profile curve to curve contact and offer mass as well as inertia data via solid gear models. This simulation process combines the two models to complete the gear driving analysis. In order to verify the validity of the method presented, both theoretical derivation and numerical simulation on a runaway escapement are conducted. The results show that the computational efficiency of the mixed model method is 1.4 times over the traditional method which contains solid to solid contact. Meanwhile, the simulation results are more closely to theoretical calculations. Consequently, mixed model method has a high application value regarding to the study of the dynamics of gear mechanism.

  13. Cyclic fatigue resistance of four nickel-titanium rotary instruments: a comparative study

    PubMed Central

    Pedullà, Eugenio; Plotino, Gianluca; Grande, Nicola Maria; Pappalardo, Alfio; Rapisarda, Ernesto

    2012-01-01

    Summary Aims The aim of this study is to investigate cyclic fatigue resistance of four nickel – titanium rotary (NTR) instruments produced by a new method or traditional grinding processes. Methods Four NTR instruments from different brands were selected: group 1. Twisted File produced by a new thermal treatment of nickel – titanium alloy; group 2. Revo S SU; group 3. Mtwo and group 4. BioRaCe BR3 produced by traditional grinding processes. A total of 80 instruments (20 for each group) were tested for cyclic fatigue resistance inside a curved artificial canal with a 60 degree angle of curvature and 5 mm radius of curvature. Time to fracture (TtF) from the start of the test until the moment of file breakage and the length of the fractured tip was recorded for each instrument. Means and standard deviations (SD) of TtF and fragment length were calculated. Data were subjected to one-way analysis of variance (ANOVA). Results Group 1 (Twisted File) showed the highest value of TtF means. Cyclic fatigue resistance of Twisted File and Mtwo was significantly higher than group 2 (Revo S SU) and 4 (BioRace BR3), while no significant differences were found between group 1 (Twisted File) and 3 (Mtwo) or group 2 (Revo S SU) and 4 (BioRaCe BR3). Conclusions The cyclic fatigue resistance of Twisted File was significantly frigher than instruments produced with traditional grinding process except of Mtwo files. PMID:23087787

  14. Method and algorithm for image processing

    DOEpatents

    He, George G.; Moon, Brain D.

    2003-12-16

    The present invention is a modified Radon transform. It is similar to the traditional Radon transform for the extraction of line parameters and similar to traditional slant stack for the intensity summation of pixels away from a given pixel, for example ray paths that spans 360 degree at a given grid in the time and offset domain. However, the present invention differs from these methods in that the intensity and direction of a composite intensity for each pixel are maintained separately instead of combined after the transformation. An advantage of this approach is elimination of the work required to extract the line parameters in the transformed domain. The advantage of the modified Radon Transform method is amplified when many lines are present in the imagery or when the lines are just short segments which both occur in actual imagery.

  15. MFAHP: A novel method on the performance evaluation of the industrial wireless networked control system

    NASA Astrophysics Data System (ADS)

    Wu, Linqin; Xu, Sheng; Jiang, Dezhi

    2015-12-01

    Industrial wireless networked control system has been widely used, and how to evaluate the performance of the wireless network is of great significance. In this paper, considering the shortcoming of the existing performance evaluation methods, a comprehensive performance evaluation method of networks multi-indexes fuzzy analytic hierarchy process (MFAHP) combined with the fuzzy mathematics and the traditional analytic hierarchy process (AHP) is presented. The method can overcome that the performance evaluation is not comprehensive and subjective. Experiments show that the method can reflect the network performance of real condition. It has direct guiding role on protocol selection, network cabling, and node setting, and can meet the requirements of different occasions by modifying the underlying parameters.

  16. Theoretical approaches to creation of robotic coal mines based on the synthesis of simulation technologies

    NASA Astrophysics Data System (ADS)

    Fryanov, V. N.; Pavlova, L. D.; Temlyantsev, M. V.

    2017-09-01

    Methodological approaches to theoretical substantiation of the structure and parameters of robotic coal mines are outlined. The results of mathematical and numerical modeling revealed the features of manifestation of geomechanical and gas dynamic processes in the conditions of robotic mines. Technological solutions for the design and manufacture of technical means for robotic mine are adopted using the method of economic and mathematical modeling and in accordance with the current regulatory documents. For a comparative performance evaluation of technological schemes of traditional and robotic mines, methods of cognitive modeling and matrix search for subsystem elements in the synthesis of a complex geotechnological system are applied. It is substantiated that the process of technical re-equipment of a traditional mine with a phased transition to a robotic mine will reduce unit costs by almost 1.5 times with a significant social effect due to a reduction in the number of personnel engaged in hazardous work.

  17. Traditional and nontraditional evaluations of student outcomes in a practical final examination of veterinary radiology.

    PubMed

    Koskinen, Heli I

    2010-01-01

    The Faculty of Veterinary Medicine at the University of Helsinki recognized the lack of systems to measure the quality of education. At the department level, this meant lack of systems to measure the quality of students' outcomes. The aim of this article was to compare the quality of outcomes of a final examination in veterinary radiology by calculating the correlations between traditional (quantitative scores traditionally given by veterinary teachers) and nontraditional (qualitative Structure of the Observed Learning Outcome, or SOLO, method) grading results. Evaluation of the quality of the questions is also included. The results indicate that SOLO offers criteria for quality evaluation, especially for questions. A correlation of 0.60 (p<0.01) existed between qualitative and quantitative estimations, and a correlation of 0.79 (p<0.01) existed between evaluators, both using traditional scores. Two suggestions for a better system to evaluate quality in the future: First, development of problem-solving skills during the learning process should also be assessed. Second, both the scoring of factual correctness of answers (knowledge) and the grammatical structure of an answer and the quality of presentation should be included in the quality evaluation process.

  18. Accuracy and reliability testing of two methods to measure internal rotation of the glenohumeral joint.

    PubMed

    Hall, Justin M; Azar, Frederick M; Miller, Robert H; Smith, Richard; Throckmorton, Thomas W

    2014-09-01

    We compared accuracy and reliability of a traditional method of measurement (most cephalad vertebral spinous process that can be reached by a patient with the extended thumb) to estimates made with the shoulder in abduction to determine if there were differences between the two methods. Six physicians with fellowship training in sports medicine or shoulder surgery estimated measurements in 48 healthy volunteers. Three were randomly chosen to make estimates of both internal rotation measurements for each volunteer. An independent observer made objective measurements on lateral scoliosis films (spinous process method) or with a goniometer (abduction method). Examiners were blinded to objective measurements as well as to previous estimates. Intraclass coefficients for interobserver reliability for the traditional method averaged 0.75, indicating good agreement among observers. The difference in vertebral level estimated by the examiner and the actual radiographic level averaged 1.8 levels. The intraclass coefficient for interobserver reliability for the abduction method averaged 0.81 for all examiners, indicating near-perfect agreement. Confidence intervals indicated that estimates were an average of 8° different from the objective goniometer measurements. Pearson correlation coefficients of intraobserver reliability for the abduction method averaged 0.94, indicating near-perfect agreement within observers. Confidence intervals demonstrated repeated estimates between 5° and 10° of the original. Internal rotation estimates made with the shoulder abducted demonstrated interobserver reliability superior to that of spinous process estimates, and reproducibility was high. On the basis of this finding, we now take glenohumeral internal rotation measurements with the shoulder in abduction and use a goniometer to maximize accuracy and objectivity. Copyright © 2014 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Mosby, Inc. All rights reserved.

  19. Research on subsurface deformed layer in ultra-precision cutting of single crystal copper by focused ion beam etching method

    NASA Astrophysics Data System (ADS)

    Chen, Y.; Huang, X. J.; Kong, J. X.

    2018-03-01

    In this paper, the focused ion beam was used to study the subsurface deformed layer of single crystal copper caused by the nanoscale single-point diamond fly cutting, and the possibility of using nanometer ultra-precision cutting to remove the larger deformation layer caused by traditional rough cutting process was explored. The maximum cutting thickness of single-point diamond cutting was about 146 nm, and the surface of the single-crystal copper after cutting was etched and observed by using the focused ion beam method. It was found that the morphology of the near-surface layer and the intermediate layer of the copper material were larger differences: the near-surface of the material was smaller and more compact, and the intermediate material layer of the material was more coarse sparse. The results showed that the traditional precision cutting would residual significant subsurface deformed layer and the thickness was on micron level. Even more, the subsurface deformed layer was obviously removed from about 12μm to 5μm after single-point diamond fly cutting in this paper. This paper proved that the large-scale subsurface deformed layer caused by traditional cutting process could be removed by nanometer ultra-precision cutting. It was of great significance to further establish the method that control of the deformation of weak rigid components by reducing the depth of the subsurface deformed layers.

  20. Business Process Design Method Based on Business Event Model for Enterprise Information System Integration

    NASA Astrophysics Data System (ADS)

    Kobayashi, Takashi; Komoda, Norihisa

    The traditional business process design methods, in which the usecase is the most typical, have no useful framework to design the activity sequence with. Therefore, the design efficiency and quality vary widely according to the designer’s experience and skill. In this paper, to solve this problem, we propose the business events and their state transition model (a basic business event model) based on the language/action perspective, which is the result in the cognitive science domain. In the business process design, using this model, we decide event occurrence conditions so that every event synchronizes with each other. We also propose the design pattern to decide the event occurrence condition (a business event improvement strategy). Lastly, we apply the business process design method based on the business event model and the business event improvement strategy to the credit card issue process and estimate its effect.

  1. Isoflavone profile in soymilk as affected by soybean variety, grinding, and heat-processing methods.

    PubMed

    Zhang, Yan; Chang, Sam K C; Liu, Zhisheng

    2015-05-01

    Isoflavones impart health benefits and their overall content and profile in foods are greatly influenced at each step during processing. In this study, 2 soybean varieties (Prosoy and black soybean) were processed with 3 different grinding (ambient, cold, and hot grinding) and heating methods (traditional stove cooking, 1-phase UHT, and 2-phase UHT) for soymilk making. The results showed after cold, ambient, and hot grinding, the total isoflavones were 3917, 5013, and 5949 nmol/g for Prosoy; the total isoflavones were 4073, 3966, and 4284 nmol/g for black soybean. Grinding could significantly increase isoflavone extraction. The grinding process had a destructive effect on isoflavones and this effect varied with grinding temperature. Different heating methods had different effects on different isoflavone forms. Two soybean varieties showed distinct patterns with respect to the change of isoflavone profile during processing. © 2015 Institute of Food Technologists®

  2. Layer stacking: A novel algorithm for individual forest tree segmentation from LiDAR point clouds

    Treesearch

    Elias Ayrey; Shawn Fraver; John A. Kershaw; Laura S. Kenefic; Daniel Hayes; Aaron R. Weiskittel; Brian E. Roth

    2017-01-01

    As light detection and ranging (LiDAR) technology advances, it has become common for datasets to be acquired at a point density high enough to capture structural information from individual trees. To process these data, an automatic method of isolating individual trees from a LiDAR point cloud is required. Traditional methods for segmenting trees attempt to isolate...

  3. Processing Electromyographic Signals to Recognize Words

    NASA Technical Reports Server (NTRS)

    Jorgensen, C. C.; Lee, D. D.

    2009-01-01

    A recently invented speech-recognition method applies to words that are articulated by means of the tongue and throat muscles but are otherwise not voiced or, at most, are spoken sotto voce. This method could satisfy a need for speech recognition under circumstances in which normal audible speech is difficult, poses a hazard, is disturbing to listeners, or compromises privacy. The method could also be used to augment traditional speech recognition by providing an additional source of information about articulator activity. The method can be characterized as intermediate between (1) conventional speech recognition through processing of voice sounds and (2) a method, not yet developed, of processing electroencephalographic signals to extract unspoken words directly from thoughts. This method involves computational processing of digitized electromyographic (EMG) signals from muscle innervation acquired by surface electrodes under a subject's chin near the tongue and on the side of the subject s throat near the larynx. After preprocessing, digitization, and feature extraction, EMG signals are processed by a neural-network pattern classifier, implemented in software, that performs the bulk of the recognition task as described.

  4. Multi-scale Slip Inversion Based on Simultaneous Spatial and Temporal Domain Wavelet Transform

    NASA Astrophysics Data System (ADS)

    Liu, W.; Yao, H.; Yang, H. Y.

    2017-12-01

    Finite fault inversion is a widely used method to study earthquake rupture processes. Some previous studies have proposed different methods to implement finite fault inversion, including time-domain, frequency-domain, and wavelet-domain methods. Many previous studies have found that different frequency bands show different characteristics of the seismic rupture (e.g., Wang and Mori, 2011; Yao et al., 2011, 2013; Uchide et al., 2013; Yin et al., 2017). Generally, lower frequency waveforms correspond to larger-scale rupture characteristics while higher frequency data are representative of smaller-scale ones. Therefore, multi-scale analysis can help us understand the earthquake rupture process thoroughly from larger scale to smaller scale. By the use of wavelet transform, the wavelet-domain methods can analyze both the time and frequency information of signals in different scales. Traditional wavelet-domain methods (e.g., Ji et al., 2002) implement finite fault inversion with both lower and higher frequency signals together to recover larger-scale and smaller-scale characteristics of the rupture process simultaneously. Here we propose an alternative strategy with a two-step procedure, i.e., firstly constraining the larger-scale characteristics with lower frequency signals, and then resolving the smaller-scale ones with higher frequency signals. We have designed some synthetic tests to testify our strategy and compare it with the traditional one. We also have applied our strategy to study the 2015 Gorkha Nepal earthquake using tele-seismic waveforms. Both the traditional method and our two-step strategy only analyze the data in different temporal scales (i.e., different frequency bands), while the spatial distribution of model parameters also shows multi-scale characteristics. A more sophisticated strategy is to transfer the slip model into different spatial scales, and then analyze the smooth slip distribution (larger scales) with lower frequency data firstly and more detailed slip distribution (smaller scales) with higher frequency data subsequently. We are now implementing the slip inversion using both spatial and temporal domain wavelets. This multi-scale analysis can help us better understand frequency-dependent rupture characteristics of large earthquakes.

  5. A resource management scenario for traditional and scientific management of pink shrimp (Farfantepenaeus paulensis) in the Patos Lagoon estuary (RS), Brazil

    PubMed Central

    2013-01-01

    Background This article aims to discuss the incorporation of traditional time in the construction of a management scenario for pink shrimp in the Patos Lagoon estuary (RS), Brazil. To meet this objective, two procedures have been adopted; one at a conceptual level and another at a methodological level. At the conceptual level, the concept of traditional time as a form of traditional ecological knowledge (TEK) was adopted. Method At the methodological level, we conduct a wide literature review of the scientific knowledge (SK) that guides recommendations for pink shrimp management by restricting the fishing season in the Patos Lagoon estuary; in addition, we review the ethno-scientific literature which describes traditional calendars as a management base for artisanal fishers in the Patos Lagoon estuary. Results Results demonstrate that TEK and SK describe similar estuarine biological processes, but are incommensurable at a resource management level. On the other hand, the construction of a “management scenario” for pink shrimp is possible through the development of “criteria for hierarchies of validity” which arise from a productive dialog between SK and TEK. Conclusions The commensurable and the incommensurable levels reveal different basis of time-space perceptions between traditional ecological knowledge and scientific knowledge. Despite incommensurability at the management level, it is possible to establish guidelines for the construction of “management scenarios” and to support a co-management process. PMID:23311826

  6. Use of overburden rocks from open-pit coal mines and waste coals of Western Siberia for ceramic brick production with a defect-free structure

    NASA Astrophysics Data System (ADS)

    Stolboushkin, A. Yu; Ivanov, A. I.; Storozhenko, G. I.; Syromyasov, V. A.; Akst, D. V.

    2017-09-01

    The rational technology for the production of ceramic bricks with a defect-free structure from coal mining and processing wastes was developed. The results of comparison of physical and mechanical properties and the structure of ceramic bricks manufactured from overburden rocks and waste coal with traditional for semi-dry pressing mass preparation and according to the developed method are given. It was established that a homogeneous, defect-free brick texture obtained from overburden rocks of open-pit mines and waste coal improves the quality of ceramic wall materials produced by the method of compression molding by more than 1.5 times compared to the brick with a traditional mass preparation.

  7. Feasibility study for converting traditional line assembly into work cells for termination of fiber optics cable

    NASA Astrophysics Data System (ADS)

    Caldeira, Rylan; Honnungar, Sunilkumar

    2018-04-01

    Most of small to medium industries tend to follow traditional systems of manufacturing which aims at maximum resource utilization irrespective of giving attention to customers volatile demand. In recent times manufacturing is being shifted to be consumers centered, with intense competition among industries to satisfy the customer needs in the required quantity and at the right time. To achieve this, companies investigate the possibility of implementation of cellular manufacturing which is characterized by high variety with optimum usage of resources. Cellular layout coupled with the application of lean methodology, places focus on the production process rather than the production methods so as to identify the wastage and apply methods to further improve productivity.

  8. Development and Application of Collaborative Optimization Software for Plate - fin Heat Exchanger

    NASA Astrophysics Data System (ADS)

    Chunzhen, Qiao; Ze, Zhang; Jiangfeng, Guo; Jian, Zhang

    2017-12-01

    This paper introduces the design ideas of the calculation software and application examples for plate - fin heat exchangers. Because of the large calculation quantity in the process of designing and optimizing heat exchangers, we used Visual Basic 6.0 as a software development carrier to design a basic calculation software to reduce the calculation quantity. Its design condition is plate - fin heat exchanger which was designed according to the boiler tail flue gas. The basis of the software is the traditional design method of the plate-fin heat exchanger. Using the software for design and calculation of plate-fin heat exchangers, discovery will effectively reduce the amount of computation, and similar to traditional methods, have a high value.

  9. Research on intelligent machine self-perception method based on LSTM

    NASA Astrophysics Data System (ADS)

    Wang, Qiang; Cheng, Tao

    2018-05-01

    In this paper, we use the advantages of LSTM in feature extraction and processing high-dimensional and complex nonlinear data, and apply it to the autonomous perception of intelligent machines. Compared with the traditional multi-layer neural network, this model has memory, can handle time series information of any length. Since the multi-physical domain signals of processing machines have a certain timing relationship, and there is a contextual relationship between states and states, using this deep learning method to realize the self-perception of intelligent processing machines has strong versatility and adaptability. The experiment results show that the method proposed in this paper can obviously improve the sensing accuracy under various working conditions of the intelligent machine, and also shows that the algorithm can well support the intelligent processing machine to realize self-perception.

  10. A Complex Network Approach to Stylometry

    PubMed Central

    Amancio, Diego Raphael

    2015-01-01

    Statistical methods have been widely employed to study the fundamental properties of language. In recent years, methods from complex and dynamical systems proved useful to create several language models. Despite the large amount of studies devoted to represent texts with physical models, only a limited number of studies have shown how the properties of the underlying physical systems can be employed to improve the performance of natural language processing tasks. In this paper, I address this problem by devising complex networks methods that are able to improve the performance of current statistical methods. Using a fuzzy classification strategy, I show that the topological properties extracted from texts complement the traditional textual description. In several cases, the performance obtained with hybrid approaches outperformed the results obtained when only traditional or networked methods were used. Because the proposed model is generic, the framework devised here could be straightforwardly used to study similar textual applications where the topology plays a pivotal role in the description of the interacting agents. PMID:26313921

  11. Image gathering and restoration - Information and visual quality

    NASA Technical Reports Server (NTRS)

    Mccormick, Judith A.; Alter-Gartenberg, Rachel; Huck, Friedrich O.

    1989-01-01

    A method is investigated for optimizing the end-to-end performance of image gathering and restoration for visual quality. To achieve this objective, one must inevitably confront the problems that the visual quality of restored images depends on perceptual rather than mathematical considerations and that these considerations vary with the target, the application, and the observer. The method adopted in this paper is to optimize image gathering informationally and to restore images interactively to obtain the visually preferred trade-off among fidelity resolution, sharpness, and clarity. The results demonstrate that this method leads to significant improvements in the visual quality obtained by the traditional digital processing methods. These traditional methods allow a significant loss of visual quality to occur because they treat the design of the image-gathering system and the formulation of the image-restoration algorithm as two separate tasks and fail to account for the transformations between the continuous and the discrete representations in image gathering and reconstruction.

  12. A Novel Adjuvant to the Resident Selection Process: the Hartman Value Profile

    PubMed Central

    Cone, Jeffrey D.; Byrum, C. Stephen; Payne, Wyatt G.; Smith, David J.

    2012-01-01

    Objectives: The goal of resident selection is twofold: (1) select candidates who will be successful residents and eventually successful practitioners and (2) avoid selecting candidates who will be unsuccessful residents and/or eventually unsuccessful practitioners. Traditional tools used to select residents have well-known limitations. The Hartman Value Profile (HVP) is a proven adjuvant tool to predicting future performance in candidates for advanced positions in the corporate setting. Methods: No literature exists to indicate use of the HVP for resident selection. Results: The HVP evaluates the structure and the dynamics of an individual value system. Given the potential impact, we implemented its use beginning in 2007 as an adjuvant tool to the traditional selection process. Conclusions: Experience gained from incorporating the HVP into the residency selection process suggests that it may add objectivity and refinement in predicting resident performance. Further evaluation is warranted with longer follow-up times. PMID:22720114

  13. Impact of agile methodologies on team capacity in automotive radio-navigation projects

    NASA Astrophysics Data System (ADS)

    Prostean, G.; Hutanu, A.; Volker, S.

    2017-01-01

    The development processes used in automotive radio-navigation projects are constantly under adaption pressure. While the software development models are based on automotive production processes, the integration of peripheral components into an automotive system will trigger a high number of requirement modifications. The use of traditional development models in automotive industry will bring team’s development capacity to its boundaries. The root cause lays in the inflexibility of actual processes and their adaption limits. This paper addresses a new project management approach for the development of radio-navigation projects. The understanding of weaknesses of current used models helped us in development and integration of agile methodologies in traditional development model structure. In the first part we focus on the change management methods to reduce request for change inflow. Established change management risk analysis processes enables the project management to judge the impact of a requirement change and also gives time to the project to implement some changes. However, in big automotive radio-navigation projects the saved time is not enough to implement the large amount of changes, which are submitted to the project. In the second phase of this paper we focus on increasing team capacity by integrating at critical project phases agile methodologies into the used traditional model. The overall objective of this paper is to prove the need of process adaption in order to solve project team capacity bottlenecks.

  14. Assessing and Evaluating Multidisciplinary Translational Teams: A Mixed Methods Approach

    PubMed Central

    Wooten, Kevin C.; Rose, Robert M.; Ostir, Glenn V.; Calhoun, William J.; Ameredes, Bill T.; Brasier, Allan R.

    2014-01-01

    A case report illustrates how multidisciplinary translational teams can be assessed using outcome, process, and developmental types of evaluation using a mixed methods approach. Types of evaluation appropriate for teams are considered in relation to relevant research questions and assessment methods. Logic models are applied to scientific projects and team development to inform choices between methods within a mixed methods design. Use of an expert panel is reviewed, culminating in consensus ratings of 11 multidisciplinary teams and a final evaluation within a team type taxonomy. Based on team maturation and scientific progress, teams were designated as: a) early in development, b) traditional, c) process focused, or d) exemplary. Lessons learned from data reduction, use of mixed methods, and use of expert panels are explored. PMID:24064432

  15. [Scientific connotation of processing Bombyx Batryticatus under high temperature].

    PubMed

    Ma, Li; Wang, Xuan; Ma, Lin; Wang, Man-yuan; Qiu, Feng

    2015-12-01

    The aim of this study was to elucidate the scientific connotation of Bombyx Batryticatus processing with wheat bran under high temperature. The contents of soluble protein extracted from Bombyx Batryticatus and its processed products and the limited content of AFT in Bombyx Batryticatus and the processed one were compared. The concentration of protein was measured with the Bradford methods and the difference of protein between Bombyx Batryticatus and its processed products was compared by SDS-PAGE analysis. Aflatoxin B1, B2, G1, and G2 were determined by reversed-phase HPLC. The results showed that the soluble protein content of Bombyx Batryticatus and its processed products were (47.065 +/- 0.249), (29.756 +/- 1.961) mg x g(-1), correspondingly. Analysis of protein gel electrophoresis showed that there were no significant differences between the crude and processed one in protein varieties. 6 bands were detected: 31.90, 26.80, 18.71, 15.00, 10.18, 8.929 kDa. Below 10 kDa, the color of bands of the processed one was deeper than the crude one, which demonstrate that macromolecular protein was degradated into micromolecule. The content of AFG1, AFB1, AFG2, AFB2 were 0.382, 0.207, 0.223, 0.073 g x kg(-1), not exceeded 5 microg x kg(-1) while the processed one was not detected. Through processing with wheat bran under high temperature, the content of soluble protein in Bombyx Batryticatus decreased, the processing purpose for alleviating drug property was achieved. Meanwhile, the limited content of aflatoxins were reduced or cleared by processing procedure or absorbed by processing auxillary material, adding the safety of the traditional Chinese Medicine. In conclusion, as a traditional processing method, bran frying Bombyx Batryticatus was scientific and reasonable.

  16. A reliable sealing method for microbatteries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Yuxing; Cartmell, Samuel; Li, Qiuyan

    2017-02-01

    With continuous downsizing of electronic devices, lithium batteries of traditional shapes cannot meet the demand where small-size high energy density batteries are needed. Conventional sealing methods become increasingly difficult to apply and impose high processing cost as the size of batteries decreases. In this report, a facile sealing method is proposed and demonstrated in CFx/Li mini-batteries. The method employs a temporary barrier to liquid electrolytes while relies on the epoxies/cell casings bond for the hermetic sealing. Cells sealed by this method show no degradation for an extended period of storage time.

  17. A study for high accuracy measurement of residual stress by deep hole drilling technique

    NASA Astrophysics Data System (ADS)

    Kitano, Houichi; Okano, Shigetaka; Mochizuki, Masahito

    2012-08-01

    The deep hole drilling technique (DHD) received much attention in recent years as a method for measuring through-thickness residual stresses. However, some accuracy problems occur when residual stress evaluation is performed by the DHD technique. One of the reasons is that the traditional DHD evaluation formula applies to the plane stress condition. The second is that the effects of the plastic deformation produced in the drilling process and the deformation produced in the trepanning process are ignored. In this study, a modified evaluation formula, which is applied to the plane strain condition, is proposed. In addition, a new procedure is proposed which can consider the effects of the deformation produced in the DHD process by investigating the effects in detail by finite element (FE) analysis. Then, the evaluation results obtained by the new procedure are compared with that obtained by traditional DHD procedure by FE analysis. As a result, the new procedure evaluates the residual stress fields better than the traditional DHD procedure when the measuring object is thick enough that the stress condition can be assumed as the plane strain condition as in the model used in this study.

  18. Use of Traditional Birth Practices by Chinese Women in the United States.

    PubMed

    Saito, Maki; Lyndon, Audrey

    The purpose of our study was to explore how foreign-born Chinese women living in California engage in various traditional and American birth practices. A descriptive qualitative study was conducted using a grounded theory approach. Chinese women from Mainland China, Hong Kong, and Taiwan who had childbirth experiences in the United States were purposively sampled. Semistructured interviews were conducted with 13 women, with follow-up interviews with 5 women. Interview data were analyzed using grounded theory according to the method of Strauss and Corbin. There are many traditional practices for pregnancy and childbirth. Women investigated the traditions through various means, and built their own perspective on each tradition by integrating an evaluation of the Chinese perspective and an evaluation of the American perspective. Women considered several factors in the process of evaluating the Chinese and American perspectives to reach their own integrated perspective on each tradition. These factors included whether or not the tradition made sense to them, how the traditional practice affected their comfort, nature of available options, attitudes of female elders, previous experiences of their peers and themselves, and outcomes of temporary trials of traditional or nontraditional practices. Healthcare providers should respect women's diverse perspectives on traditional practices and encourage flexible arrangements. Including the elder generation in health education may be useful in helping women manage conflicts and to support their decisions.

  19. The Building Commissioning Handbook.

    ERIC Educational Resources Information Center

    Heinz, John A.; Casault, Rick

    This book discusses building commissioning, which is the process of certifying that a new facility meets the required specifications. As buildings have become more complex, the traditional methods for building start-up and final acceptance have been proven inadequate, and building commissioning has been developed, which often necessitates the use…

  20. Classroom Control: Some Cybernetic Comments on the Possible and the Impossible.

    ERIC Educational Resources Information Center

    Robinson, Michael

    1979-01-01

    Application of cybernetic laws and information processing principles suggests that traditional and modern teaching methods are radically incompatible, in the sense that techniques developed in the one cannot be transferred to the other without dislocation of the system as a whole. (Author/WBC)

  1. Community, know thyself: caring about place.

    Treesearch

    Sally Duncan

    2000-01-01

    Traditional scientific assessments have limitations in providing full understanding of the potential impacts forest management has on communities. Much of the knowledge communities have of themselves is inaccessible to quantitative methods but can be provided through participatory processes, or what is termed "civic science." Self-assessment by communities,...

  2. Simulation Techniques in Training College Administrators.

    ERIC Educational Resources Information Center

    Fincher, Cameron

    Traditional methods of recruitment and selection in academic administration have not placed an emphasis on formal training or preparation but have relied heavily on informal notions of experiential learning. Simulation as a device for representing complex processes in a manageable form, gaming as an organizing technique for training and…

  3. [Development of whole process quality control and management system of traditional Chinese medicine decoction pieces based on traditional Chinese medicine quality tree].

    PubMed

    Yu, Wen-Kang; Dong, Ling; Pei, Wen-Xuan; Sun, Zhi-Rong; Dai, Jun-Dong; Wang, Yun

    2017-12-01

    The whole process quality control and management of traditional Chinese medicine (TCM) decoction pieces is a system engineering, involving the base environment, seeds and seedlings, harvesting, processing and other multiple steps, so the accurate identification of factors in TCM production process that may induce the quality risk, as well as reasonable quality control measures are very important. At present, the concept of quality risk is mainly concentrated in the aspects of management and regulations, etc. There is no comprehensive analysis on possible risks in the quality control process of TCM decoction pieces, or analysis summary of effective quality control schemes. A whole process quality control and management system for TCM decoction pieces based on TCM quality tree was proposed in this study. This system effectively combined the process analysis method of TCM quality tree with the quality risk management, and can help managers to make real-time decisions while realizing the whole process quality control of TCM. By providing personalized web interface, this system can realize user-oriented information feedback, and was convenient for users to predict, evaluate and control the quality of TCM. In the application process, the whole process quality control and management system of the TCM decoction pieces can identify the related quality factors such as base environment, cultivation and pieces processing, extend and modify the existing scientific workflow according to their own production conditions, and provide different enterprises with their own quality systems, to achieve the personalized service. As a new quality management model, this paper can provide reference for improving the quality of Chinese medicine production and quality standardization. Copyright© by the Chinese Pharmaceutical Association.

  4. [Effect of gas-turbine green discoloring and drying processing methods on herbal quality of tetraploid Lonicerae Japonicae Flos].

    PubMed

    Hu, Xuan; Li, Wei-dong; Li, Ou; Hao, Jiang-bo; Liu, Jia-kun

    2012-09-01

    To study the effect of gas-turbine green discoloring and drying processing method on the quality of various Lonicerae Japonicae Flos herbs. DIKMA DiamonsilTM-C18 column (4.6 mm x 250 mm, 5 microm) was adopted using HPLC Waters 1525 and eluted with acetonitrile and 0.1% phosphate acid as the mobile phase. The flow rate was 1.0 mL x min(-1) , the column temperature was 25 degrees C the detection wavelength was 355 nm. After being processed by the gas-turbine green discoloring and drying method, tetraploid Lonicerae Japonicae Flos showed a green color. The contents of chlorogenic acid and galuteolin were 5.31% and 0.105% , both significantly higher by 18.0% and 32.1% than those of diploid Lonicerae Japonicae Flos processed by the same method. The content of chlorogenic acid in tetraploid Lonicerae Japonicae Flos processed the gas-turbine green discoloring and drying method were also remarkably higher than that of tetraploid and diploid Lonicerae Japonicae Flos processed by traditional processing method of natural drying. The gas-turbine green discoloring and drying processing method is a new-type drying method suitable for tetraploid Lonicerae Japonicae Flos. Under the condition of gas-turbine green discoloring and drying processing, tetraploid Lonicerae Japonicae Flos shows much higher quality than Lonicerae Japonicae Flos, suggesting that it is a good variety worth popularizing and applying.

  5. Stratospheric Aerosol and Gas Experiment, SAGE III on ISS, An Earth Science Mission on the International Space Station, Schedule Risk Analysis, A Project Perspective

    NASA Technical Reports Server (NTRS)

    Bonine, Lauren

    2015-01-01

    The presentation provides insight into the schedule risk analysis process used by the Stratospheric Aerosol and Gas Experiment III on the International Space Station Project. The presentation focuses on the schedule risk analysis process highlighting the methods for identification of risk inputs, the inclusion of generic risks identified outside the traditional continuous risk management process, and the development of tailored analysis products used to improve risk informed decision making.

  6. Comparison of Chemical Sensitivity of Fresh and Long-Stored Heat Resistant Neosartorya fischeri Environmental Isolates Using BIOLOG Phenotype MicroArray System

    PubMed Central

    Panek, Jacek; Frąc, Magdalena; Bilińska-Wielgus, Nina

    2016-01-01

    Spoilage of heat processed food and beverage by heat resistant fungi (HRF) is a major problem for food industry in many countries. Neosartorya fischeri is the leading source of spoilage in thermally processed products. Its resistance to heat processing and toxigenicity makes studies about Neosartorya fischeri metabolism and chemical sensitivity essential. In this study chemical sensitivity of two environmental Neosartorya fischeri isolates were compared. One was isolated from canned apples in 1923 (DSM3700), the other from thermal processed strawberry product in 2012 (KC179765), used as long-stored and fresh isolate, respectively. The study was conducted using Biolog Phenotype MicroArray platforms of chemical sensitivity panel and traditional hole-plate method. The study allowed for obtaining data about Neosartorya fischeri growth inhibitors. The fresh isolate appeared to be much more resistant to chemical agents than the long-stored isolate. Based on phenotype microarray assay nitrogen compounds, toxic cations and membrane function compounds were the most effective in growth inhibition of N. fischeri isolates. According to the study zaragozic acid A, thallium(I) acetate and sodium selenate were potent and promising N. fischeri oriented fungicides which was confirmed by both chemical sensitivity microplates panel and traditional hole-plate methods. PMID:26815302

  7. The Impact of Social Media on Dissemination and Implementation of Clinical Practice Guidelines: A Longitudinal Observational Study

    PubMed Central

    Gronseth, Gary; Dubinsky, Richard; Penfold-Murray, Rebecca; Cox, Julie; Bever Jr, Christopher; Martins, Yolanda; Rheaume, Carol; Shouse, Denise; Getchius, Thomas SD

    2015-01-01

    Background Evidence-based clinical practice guidelines (CPGs) are statements that provide recommendations to optimize patient care for a specific clinical problem or question. Merely reading a guideline rarely leads to implementation of recommendations. The American Academy of Neurology (AAN) has a formal process of guideline development and dissemination. The last few years have seen a burgeoning of social media such as Facebook, Twitter, and LinkedIn, and newer methods of dissemination such as podcasts and webinars. The role of these media in guideline dissemination has not been studied. Systematic evaluation of dissemination methods and comparison of the effectiveness of newer methods with traditional methods is not available. It is also not known whether specific dissemination methods may be more effectively targeted to specific audiences. Objective Our aim was to (1) develop an innovative dissemination strategy by adding social media-based dissemination methods to traditional methods for the AAN clinical practice guidelines “Complementary and alternative medicine in multiple sclerosis” (“CAM in MS”) and (2) evaluate whether the addition of social media outreach improves awareness of the CPG and knowledge of CPG recommendations, and affects implementation of those recommendations. Methods Outcomes were measured by four surveys in each of the two target populations: patients and physicians/clinicians (“physicians”). The primary outcome was the difference in participants’ intent to discuss use of complementary and alternative medicine (CAM) with their physicians or patients, respectively, after novel dissemination, as compared with that after traditional dissemination. Secondary outcomes were changes in awareness of the CPG, knowledge of CPG content, and behavior regarding CAM use in multiple sclerosis (MS). Results Response rates were 25.08% (622/2480) for physicians and 43.5% (348/800) for patients. Awareness of the CPG increased after traditional dissemination (absolute difference, 95% confidence interval: physicians 36%, 95% CI 25-46, and patients 10%, 95% CI 1-11) but did not increase further after novel dissemination (physicians 0%, 95% CI -11 to 11, and patients -4%, 95% CI -6 to 14). Intent to discuss CAM also increased after traditional dissemination but did not change after novel dissemination (traditional: physicians 12%, 95% CI 2-22, and patients 19%, 95% CI 3-33; novel: physicians 11%, 95% CI -1 to -21, and patients -8%, 95% CI -22 to 8). Knowledge of CPG recommendations and behavior regarding CAM use in MS did not change after either traditional dissemination or novel dissemination. Conclusions Social media-based dissemination methods did not confer additional benefit over print-, email-, and Internet-based methods in increasing CPG awareness and changing intent in physicians or patients. Research on audience selection, message formatting, and message delivery is required to utilize Web 2.0 technologies optimally for dissemination. PMID:26272267

  8. Product-oriented Software Certification Process for Software Synthesis

    NASA Technical Reports Server (NTRS)

    Nelson, Stacy; Fischer, Bernd; Denney, Ewen; Schumann, Johann; Richardson, Julian; Oh, Phil

    2004-01-01

    The purpose of this document is to propose a product-oriented software certification process to facilitate use of software synthesis and formal methods. Why is such a process needed? Currently, software is tested until deemed bug-free rather than proving that certain software properties exist. This approach has worked well in most cases, but unfortunately, deaths still occur due to software failure. Using formal methods (techniques from logic and discrete mathematics like set theory, automata theory and formal logic as opposed to continuous mathematics like calculus) and software synthesis, it is possible to reduce this risk by proving certain software properties. Additionally, software synthesis makes it possible to automate some phases of the traditional software development life cycle resulting in a more streamlined and accurate development process.

  9. Interferometric architectures based All-Optical logic design methods and their implementations

    NASA Astrophysics Data System (ADS)

    Singh, Karamdeep; Kaur, Gurmeet

    2015-06-01

    All-Optical Signal Processing is an emerging technology which can avoid costly Optical-electronic-optical (O-E-O) conversions which are usually compulsory in traditional Electronic Signal Processing systems, thus greatly enhancing operating bit rate with some added advantages such as electro-magnetic interference immunity and low power consumption etc. In order to implement complex signal processing tasks All-Optical logic gates are required as backbone elements. This review describes the advances in the field of All-Optical logic design methods based on interferometric architectures such as Mach-Zehnder Interferometer (MZI), Sagnac Interferometers and Ultrafast Non-Linear Interferometer (UNI). All-Optical logic implementations for realization of arithmetic and signal processing applications based on each interferometric arrangement are also presented in a categorized manner.

  10. Characterization of Korean Red Ginseng (Panax ginseng Meyer): History, preparation method, and chemical composition

    PubMed Central

    Lee, Sang Myung; Bae, Bong-Seok; Park, Hee-Weon; Ahn, Nam-Geun; Cho, Byung-Gu; Cho, Yong-Lae; Kwak, Yi-Seong

    2015-01-01

    It has been reported that Korean Red Ginseng has been manufactured for 1,123 y as described in the GoRyeoDoGyeong record. The Korean Red Ginseng manufactured by the traditional preparation method has its own chemical component characteristics. The ginsenoside content of the red ginseng is shown as Rg1: 3.3 mg/g, Re: 2.0 mg/g, Rb1: 5.8 mg/g, Rc:1.7 mg/g, Rb2: 2.3 mg/g, and Rd: 0.4 mg/g, respectively. It is known that Korean ginseng generally consists of the main root and the lateral or fine roots at a ratio of about 75:25. Therefore, the red ginseng extract is prepared by using this same ratio of the main root and lateral or fine roots and processed by the historical traditional medicine prescription. The red ginseng extract is prepared through a water extraction (90°C for 14–16 h) and concentration process (until its final concentration is 70–73 Brix at 50–60°C). The ginsenoside contents of the red ginseng extract are shown as Rg1: 1.3 mg/g, Re: 1.3 mg/g, Rb1: 6.4 mg/g, Rc:2.5 mg/g, Rb2: 2.3 mg/g, and Rd: 0.9 mg/g, respectively. Arginine-fructose-glucose (AFG) is a specific amino-sugar that can be produced by chemical reaction of the process when the fresh ginseng is converted to red ginseng. The content of AFG is 1.0–1.5% in red ginseng. Acidic polysaccharide, which has been known as an immune activator, is at levels of 4.5–7.5% in red ginseng. Therefore, we recommended that the chemical profiles of Korean Red Ginseng made through the defined traditional method should be well preserved and it has had its own chemical characteristics since its traditional development. PMID:26869832

  11. Evaluating a voice recognition system: finding the right product for your department.

    PubMed

    Freeh, M; Dewey, M; Brigham, L

    2001-06-01

    The Department of Radiology at the University of Utah Health Sciences Center has been in the process of transitioning from the traditional film-based department to a digital imaging department for the past 2 years. The department is now transitioning from the traditional method of dictating reports (dictation by radiologist to transcription to review and signing by radiologist) to a voice recognition system. The transition to digital operations will not be complete until we have the ability to directly interface the dictation process with the image review process. Voice recognition technology has advanced to the level where it can and should be an integral part of the new way of working in radiology and is an integral part of an efficient digital imaging department. The transition to voice recognition requires the task of identifying the product and the company that will best meet a department's needs. This report introduces the methods we used to evaluate the vendors and the products available as we made our purchasing decision. We discuss our evaluation method and provide a checklist that can be used by other departments to assist with their evaluation process. The criteria used in the evaluation process fall into the following major categories: user operations, technical infrastructure, medical dictionary, system interfaces, service support, cost, and company strength. Conclusions drawn from our evaluation process will be detailed, with the intention being to shorten the process for others as they embark on a similar venture. As more and more organizations investigate the many products and services that are now being offered to enhance the operations of a radiology department, it becomes increasingly important that solid methods are used to most effectively evaluate the new products. This report should help others complete the task of evaluating a voice recognition system and may be adaptable to other products as well.

  12. Preparation and characterisation of hydrocortisone particles using a supercritical fluids extraction process.

    PubMed

    Velaga, Sitaram P; Ghaderi, Raouf; Carlfors, Johan

    2002-01-14

    Crystallisation and subsequent milling of pharmaceutical powders by traditional methods often cause variations in physicochemical properties thereby influencing bioavailability of the formulation. Crystallisation of drug substances using supercritical fluids (SFs) offers some advantages over existing traditional methods in controlling particle characteristics. The novel particle formation method, solution enhanced dispersion by supercritical (SEDS) fluids was used for the preparation of hydrocortisone (HC) particles. The influence of processing conditions on the solid-state properties of the particles was studied. HC, an anti-inflammatory corticosteroid, particles were prepared from acetone and methanol solutions using the SEDS process. The solutions were dispersed with supercritical CO(2), acting as an anti-solvent, through a specially designed co-axial nozzle into a pressured vessel maintained at a specific constant temperature and pressure. The temperatures and pressures studied were 40-90 degrees C and 90-180 bar, respectively. The relative flow rates of drug solution to CO(2) were varied between 0.002 and 0.03. Solid-state characterisation of particles included differential scanning calorimetry (DSC), X-ray powder diffraction (XRPD), solubility studies and scanning electron microscopy (SEM) examination. The aerodynamic properties of SEDS prepared particles were determined by a multistage liquid impinger (MLI). Particles produced from acetone solutions were crystalline needles, melting at 221+/-2 degrees C. Their morphology was independent of processing conditions. With methanol solutions, particles were flakes or needles depending on the processing temperature and pressure. This material melted at 216+/-1 degrees C, indicating a different crystal structure from the original material, in agreement with observed differences in the position and intensity of the XRPD peaks. The simulated lung deposition, using the MLI, for HC powder was improved after SEDS processing. It was possible to produce and control the crystallinity, morphology, and aerodynamic properties of HC particles with the SEDS technique. This method may be useful for the processing of inhalation powders.

  13. Removable partial denture alloys processed by laser-sintering technique.

    PubMed

    Alageel, Omar; Abdallah, Mohamed-Nur; Alsheghri, Ammar; Song, Jun; Caron, Eric; Tamimi, Faleh

    2018-04-01

    Removable partial dentures (RPDs) are traditionally made using a casting technique. New additive manufacturing processes based on laser sintering has been developed for quick fabrication of RPDs metal frameworks at low cost. The objective of this study was to characterize the mechanical, physical, and biocompatibility properties of RPD cobalt-chromium (Co-Cr) alloys produced by two laser-sintering systems and compare them to those prepared using traditional casting methods. The laser-sintered Co-Cr alloys were processed by the selective laser-sintering method (SLS) and the direct metal laser-sintering (DMLS) method using the Phenix system (L-1) and EOS system (L-2), respectively. L-1 and L-2 techniques were 8 and 3.5 times more precise than the casting (CC) technique (p < 0.05). Co-Cr alloys processed by L-1 and L-2 showed higher (p < 0.05) hardness (14-19%), yield strength (10-13%), and fatigue resistance (71-72%) compared to CC alloys. This was probably due to their smaller grain size and higher microstructural homogeneity. All Co-Cr alloys exhibited low porosity (2.1-3.3%); however, pore distribution was more homogenous in L-1 and L-2 alloys when compared to CC alloys. Both laser-sintered and cast alloys were biocompatible. In conclusion, laser-sintered alloys are more precise and present better mechanical and fatigue properties than cast alloys for RPDs. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 1174-1185, 2018. © 2017 Wiley Periodicals, Inc.

  14. Near-Zero Emissions Oxy-Combustion Flue Gas Purification Task 2: SOx/Nox/Hg Removal for High Sulfur Coal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nick Degenstein; Minish Shah; Doughlas Louie

    2012-05-01

    The goal of this project is to develop a near-zero emissions flue gas purification technology for existing PC (pulverized coal) power plants that are retrofitted with oxy-combustion technology. The objective of Task 2 of this project was to evaluate an alternative method of SOx, NOx and Hg removal from flue gas produced by burning high sulfur coal in oxy-combustion power plants. The goal of the program was not only to investigate a new method of flue gas purification but also to produce useful acid byproduct streams as an alternative to using a traditional FGD and SCR for flue gas processing.more » During the project two main constraints were identified that limit the ability of the process to achieve project goals. 1) Due to boiler island corrosion issues >60% of the sulfur must be removed in the boiler island with the use of an FGD. 2) A suitable method could not be found to remove NOx from the concentrated sulfuric acid product, which limits sale-ability of the acid, as well as the NOx removal efficiency of the process. Given the complexity and safety issues inherent in the cycle it is concluded that the acid product would not be directly saleable and, in this case, other flue gas purification schemes are better suited for SOx/NOx/Hg control when burning high sulfur coal, e.g. this project's Task 3 process or a traditional FGD and SCR.« less

  15. Collision Visualization of a Laser-Scanned Point Cloud of Streets and a Festival Float Model Used for the Revival of a Traditional Procession Route

    NASA Astrophysics Data System (ADS)

    Li, W.; Shigeta, K.; Hasegawa, K.; Li, L.; Yano, K.; Tanaka, S.

    2017-09-01

    Recently, laser-scanning technology, especially mobile mapping systems (MMSs), has been applied to measure 3D urban scenes. Thus, it has become possible to simulate a traditional cultural event in a virtual space constructed using measured point clouds. In this paper, we take the festival float procession in the Gion Festival that has a long history in Kyoto City, Japan. The city government plans to revive the original procession route that is narrow and not used at present. For the revival, it is important to know whether a festival float collides with houses, billboards, electric wires or other objects along the original route. Therefore, in this paper, we propose a method for visualizing the collisions of point cloud objects. The advantageous features of our method are (1) a see-through visualization with a correct depth feel that is helpful to robustly determine the collision areas, (2) the ability to visualize areas of high collision risk as well as real collision areas, and (3) the ability to highlight target visualized areas by increasing the point densities there.

  16. Rapid Freeform Sheet Metal Forming: Technology Development and System Verification

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kiridena, Vijitha; Verma, Ravi; Gutowski, Timothy

    The objective of this project is to develop a transformational RApid Freeform sheet metal Forming Technology (RAFFT) in an industrial environment, which has the potential to increase manufacturing energy efficiency up to ten times, at a fraction of the cost of conventional technologies. The RAFFT technology is a flexible and energy-efficient process that eliminates the need for having geometry-specific forming dies. The innovation lies in the idea of using the energy resource at the local deformation area which provides greater formability, process control, and process flexibility relative to traditional methods. Double-Sided Incremental Forming (DSIF), the core technology in RAFFT, ismore » a new concept for sheet metal forming. A blank sheet is clamped around its periphery and gradually deformed into a complex 3D freeform part by two strategically aligned stylus-type tools that follow a pre-described toolpath. The two tools, one on each side of the blank, can form a part with sharp features for both concave and convex shapes. Since deformation happens locally, the forming force at any instant is significantly decreased when compared to traditional methods. The key advantages of DSIF are its high process flexibility, high energy-efficiency, low capital investment, and the elimination of the need for massive amounts of die casting and machining. Additionally, the enhanced formability and process flexibility of DSIF can open up design spaces and result in greater weight savings.« less

  17. An Integrated Strategy to Qualitatively Differentiate Components of Raw and Processed Viticis Fructus Based on NIR, HPLC and UPLC-MS Analysis.

    PubMed

    Diao, Jiayin; Xu, Can; Zheng, Huiting; He, Siyi; Wang, Shumei

    2018-06-21

    Viticis Fructus is a traditional Chinese herbal drug processed by various methods to achieve different clinical purposes. Thermal treatment potentially alters chemical composition, which may impact on effectiveness and toxicity. In order to interpret the constituent discrepancies of raw versus processed (stir-fried) Viticis Fructus, a multivariate detection method (NIR, HPLC, and UPLC-MS) based on metabonomics and chemometrics was developed. Firstly, synergy interval partial least squares and partial least squares-discriminant analysis were employed to screen the distinctive wavebands (4319 - 5459 cm -1 ) based on preprocessed near-infrared spectra. Then, HPLC with principal component analysis was performed to characterize the distinction. Subsequently, a total of 49 compounds were identified by UPLC-MS, among which 42 compounds were eventually characterized as having a significant change during processing via the semiquantitative volcano plot analysis. Moreover, based on the partial least squares-discriminant analysis, 16 compounds were chosen as characteristic markers that could be in close correlation with the discriminatory near-infrared wavebands. Together, all of these characterization techniques effectively discriminated raw and processed products of Viticis Fructus. In general, our work provides an integrated way of classifying Viticis Fructus, and a strategy to explore discriminatory chemical markers for other traditional Chinese herbs, thus ensuring safety and efficacy for consumers. Georg Thieme Verlag KG Stuttgart · New York.

  18. From traditional cognitive-behavioural therapy to acceptance and commitment therapy for chronic pain: a mixed-methods study of staff experiences of change.

    PubMed

    Barker, Estelle; McCracken, Lance M

    2014-08-01

    Health care organizations, both large and small, frequently undergo processes of change. In fact, if health care organizations are to improve over time, they must change; this includes pain services. The purpose of the present study was to examine a process of change in treatment model within a specialty interdisciplinary pain service in the UK. This change entailed a switch from traditional cognitive-behavioural therapy to a form of cognitive-behavioural therapy called acceptance and commitment therapy. An anonymous online survey, including qualitative and quantitative components, was carried out approximately 15 months after the initial introduction of the new treatment model and methods. Fourteen out of 16 current clinical staff responded to the survey. Three themes emerged in qualitative analyses: positive engagement in change; uncertainty and discomfort; and group cohesion versus discord. Quantitative results from closed questions showed a pattern of uncertainty about the superiority of one model over the other, combined with more positive views on progress reflected, and the experience of personal benefits, from adopting the new model. The psychological flexibility model, the model behind acceptance and commitment therapy, may clarify both processes in patient behaviour and processes of staff experience and skilful treatment delivery. This integration of processes on both sides of treatment delivery may be a strength of acceptance and commitment therapy.

  19. Instructional Design Processes and Traditional Colleges

    ERIC Educational Resources Information Center

    Vasser, Nichole

    2010-01-01

    Traditional colleges who have implemented distance education programs would benefit from using instructional design processes to develop their courses. Instructional design processes provide the framework for designing and delivering quality online learning programs in a highly-competitive educational market. Traditional college leaders play a…

  20. [Research and development strategies in classical herbal formulae].

    PubMed

    Chen, Chang; Cheng, Jin-Tang; Liu, An

    2017-05-01

    As an outstanding representative of traditional Chinese medicine prescription, classical herbal formulae are the essence of traditional Chinese medicine great treasure. To support the development of classical herbal formulae, the state and relevant administrative departments have successively promulgated the relevant encouraged policies.But some key issues of classic herbal formulae in the development process have not reached a unified consensus and standard, and these problems were discussed in depth here.The authors discussed the registration requirements of classical herbal formulae, proposed the screening specific indicators of classical herbal formulae, determination basis of prescription and dosage,screening method of production process, and the basic principle of clinical localization, in order to bring out valuable opinions and provide a reference for classical herbal formulae development and policy formulation. Copyright© by the Chinese Pharmaceutical Association.

  1. Traditional Chinese rehabilitative therapy in the process of modernization.

    PubMed

    Zhuo, D H

    1988-01-01

    In the past few years modalities of traditional Chinese rehabilitative therapy have changed from an experimental approach towards the shaping of a modernized and scientific system. The landmark of this process is characterized by adoption of scientific methods in the appraisal of efficacy, provision of experimental evidence to unveil the mechanisms for the treatments and development of new modalities by innovation with modern technology. Recent advances in clinical and experimental studies on acupuncture, Chinese massage and manipulation, qigong, and Tai Ji exercise are reviewed, with a focus on new findings in physiological mechanisms and effects on anti-senility. Comments are made on new modalities such as 'physical therapy on acupoints'. Progress in the use of qigong (meditation therapy) in tapping mental potentials and remediating mental deficiency is also reported.

  2. Drug Delivery for Peripheral Nerve Regeneration

    DTIC Science & Technology

    2015-11-01

    components are shown in Figure 2. The solvent casting method was used for manufacturing devices, with the 75/25 PLGA pellets dissolved in acetone at a...bottom-up process that minimizes wrinkling of the sheet as it expands and contracts. Following 4 hours on a hot plate, the sheet was submerged into...glass transition temperature (40-60°C), eliminating many traditional sterilization methods like autoclaving. We evaluated deformation of the device

  3. Finite Element Method Applied to Fuse Protection Design

    NASA Astrophysics Data System (ADS)

    Li, Sen; Song, Zhiquan; Zhang, Ming; Xu, Liuwei; Li, Jinchao; Fu, Peng; Wang, Min; Dong, Lin

    2014-03-01

    In a poloidal field (PF) converter module, fuse protection is of great importance to ensure the safety of the thyristors. The fuse is pre-selected in a traditional way and then verified by finite element analysis. A 3D physical model is built by ANSYS software to solve the thermal-electric coupled problem of transient process in case of external fault. The result shows that this method is feasible.

  4. Make no mistake—errors can be controlled*

    PubMed Central

    Hinckley, C

    2003-01-01

    

 Traditional quality control methods identify "variation" as the enemy. However, the control of variation by itself can never achieve the remarkably low non-conformance rates of world class quality leaders. Because the control of variation does not achieve the highest levels of quality, an inordinate focus on these techniques obscures key quality improvement opportunities and results in unnecessary pain and suffering for patients, and embarrassment, litigation, and loss of revenue for healthcare providers. Recent experience has shown that mistakes are the most common cause of problems in health care as well as in other industrial environments. Excessive product and process complexity contributes to both excessive variation and unnecessary mistakes. The best methods for controlling variation, mistakes, and complexity are each a form of mistake proofing. Using these mistake proofing techniques, virtually every mistake and non-conformance can be controlled at a fraction of the cost of traditional quality control methods. PMID:14532368

  5. The Social Consequences of Disability: An Experiential Approach.

    ERIC Educational Resources Information Center

    Brooks, Nancy A.

    1980-01-01

    Reports on the application of experiential learning to a college level sociology course on the social consequences of disability. The course involves traditional methods such as reading/lecture/examination and more innovative approaches such as experiential learning and directing students to manage their own learning processes. (Author/DB)

  6. Diagnosis of Periodontal Diseases: Building a Bridge from Today's Methods to Tomorrow's Technology.

    ERIC Educational Resources Information Center

    Jeffcoat, Marjorie K.

    1994-01-01

    A discussion of advancements in diagnosis of periodontal diseases looks first at the screening process, reviews specific periodontal diseases and their clinical signs and symptoms, and explains both traditional and newly developed diagnostic tests. A framework for understanding the tests' clinical usefulness is also presented. (MSE)

  7. Assessing the Psychological Impact of Sociocultural Change: A Life-History Methodology.

    ERIC Educational Resources Information Center

    Schroder, Sherrie Brownstein

    The twentieth century has been an era of rapid, world-wide industrialization. Very little is known about the psychological impact of this process, and traditional assessment methods which universalize Western values are largely inappropriate. A prime example of universalizing Western characteristics is Inkeles' and Smith's popular Modernity Scales…

  8. Situated Instructional Coaching: A Case Study of Faculty Professional Development

    ERIC Educational Resources Information Center

    Czajka, Charles Doug; McConnell, David

    2016-01-01

    Background: Barriers to reforming traditional lecture-based undergraduate STEM classes are numerous and include time constraints, lack of training, and instructor's beliefs about teaching and learning. This case study documents the use of a situated instructional coaching process as a method of faculty professional development. In this model, a…

  9. Conducting Randomized Controlled Trials with Offenders in an Administrative Setting

    ERIC Educational Resources Information Center

    Ahlin, Eileen M.

    2015-01-01

    Evaluation research conducted in agencies that sanction law violators is often challenging and due process may preclude evaluators from using experimental methods in traditional criminal justice agencies such as police, courts, and corrections. However, administrative agencies often deal with the same population but are not bound by due process…

  10. Novel deboning method of chilled broiler carcasses (prior to evisceration) and its effect on meat quality

    USDA-ARS?s Scientific Manuscript database

    During traditional poultry processing, the two main sources of contamination of the broiler carcasses are (1) microorganisms on the exterior of the carcasses, that results in skin surface contamination and (2) microorganisms from the gastrointestinal contents of the carcass and subsequent cross cont...

  11. Examining Portfolio-Based Assessment in an Upper-Level Biology Course

    ERIC Educational Resources Information Center

    Ziegler, Brittany Ann

    2012-01-01

    Historically, students have been viewed as empty vessels and passive participants in the learning process but students actually are active forming their own conceptions. One way student learning is impacted is through assessment. Alternative assessment, which contrasts traditional assessment methods, takes into account how students learn by…

  12. Animation Model to Conceptualize ATP Generation: A Mitochondrial Oxidative Phosphorylation

    ERIC Educational Resources Information Center

    Jena, Ananta Kumar

    2015-01-01

    Adenosine triphosphate (ATP) is the molecular unit of intracellular energy and it is the product of oxidative phosphorylation of cellular respiration uses in cellular processes. The study explores the growth of the misconception levels amongst the learners and evaluates the effectiveness of animation model over traditional methods. The data…

  13. In the Midst of Their Journeys: Professors' Reports of Transitions in Teaching

    ERIC Educational Resources Information Center

    Langenegger, Joyce A.

    2010-01-01

    This descriptive study focused on the ways college and university professors described their transition process from reliance on traditional teaching strategies to the integration of nontraditional teaching methods in their classrooms. Study participants included 24 community college and university professors from 6 institutions in the…

  14. Effect of CorrelatedRotational Noise

    NASA Astrophysics Data System (ADS)

    Hancock, Benjamin; Wagner, Caleb; Baskaran, Aparna

    The traditional model of a self-propelled particle (SPP) is one where the body axis along which the particle travels reorients itself through rotational diffusion. If the reorientation process was driven by colored noise, instead of the standard Gaussian white noise, the resulting statistical mechanics cannot be accessed through conventional methods. In this talk we present results comparing three methods of deriving the statistical mechanics of a SPP with a reorientation process driven by colored noise. We illustrate the differences/similarities in the resulting statistical mechanics by their ability to accurately capture the particles response to external aligning fields.

  15. Multicriteria decision analysis: Overview and implications for environmental decision making

    USGS Publications Warehouse

    Hermans, Caroline M.; Erickson, Jon D.; Erickson, Jon D.; Messner, Frank; Ring, Irene

    2007-01-01

    Environmental decision making involving multiple stakeholders can benefit from the use of a formal process to structure stakeholder interactions, leading to more successful outcomes than traditional discursive decision processes. There are many tools available to handle complex decision making. Here we illustrate the use of a multicriteria decision analysis (MCDA) outranking tool (PROMETHEE) to facilitate decision making at the watershed scale, involving multiple stakeholders, multiple criteria, and multiple objectives. We compare various MCDA methods and their theoretical underpinnings, examining methods that most realistically model complex decision problems in ways that are understandable and transparent to stakeholders.

  16. [Methodology of determination of the time of death and outlooks for the further development].

    PubMed

    Novikov, P I; Vlasov, A Iu; Shved, E F; Natsentov, E O; Korshunov, N V; Belykh, S A

    2004-01-01

    A methodological analysis of diagnosing the prescription of death coming (PDC) is described in the paper. Key philosophic fundamentals for further novel and more effective methods of PDC determination are elucidated. Main requirement applicable to postmortem diagnosis are defined. Different methods of modeling the postmortem process are demonstrated by the example of cadaver cooling, i.e. in real time, by analogue computer systems and by mathematic modeling. The traditional empiric and the adaptive approaches are comparatively analyzed in modeling the postmortem processes for the PDC diagnosis. A variety of promising trends for further related research is outlined.

  17. Enhancing requirements engineering for patient registry software systems with evidence-based components.

    PubMed

    Lindoerfer, Doris; Mansmann, Ulrich

    2017-07-01

    Patient registries are instrumental for medical research. Often their structures are complex and their implementations use composite software systems to meet the wide spectrum of challenges. Commercial and open-source systems are available for registry implementation, but many research groups develop their own systems. Methodological approaches in the selection of software as well as the construction of proprietary systems are needed. We propose an evidence-based checklist, summarizing essential items for patient registry software systems (CIPROS), to accelerate the requirements engineering process. Requirements engineering activities for software systems follow traditional software requirements elicitation methods, general software requirements specification (SRS) templates, and standards. We performed a multistep procedure to develop a specific evidence-based CIPROS checklist: (1) A systematic literature review to build a comprehensive collection of technical concepts, (2) a qualitative content analysis to define a catalogue of relevant criteria, and (3) a checklist to construct a minimal appraisal standard. CIPROS is based on 64 publications and covers twelve sections with a total of 72 items. CIPROS also defines software requirements. Comparing CIPROS with traditional software requirements elicitation methods, SRS templates and standards show a broad consensus but differences in issues regarding registry-specific aspects. Using an evidence-based approach to requirements engineering for registry software adds aspects to the traditional methods and accelerates the software engineering process for registry software. The method we used to construct CIPROS serves as a potential template for creating evidence-based checklists in other fields. The CIPROS list supports developers in assessing requirements for existing systems and formulating requirements for their own systems, while strengthening the reporting of patient registry software system descriptions. It may be a first step to create standards for patient registry software system assessments. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. A novel, integrated forensic microdevice on a rotation-driven platform: Buccal swab to STR product in less than 2 h.

    PubMed

    Cox, Jordan O; DeCarmen, Teresa Sikes; Ouyang, Yiwen; Strachan, Briony; Sloane, Hillary; Connon, Cathey; Gibson, Kemper; Jackson, Kimberly; Landers, James P; Cruz, Tracey Dawson

    2016-12-01

    This work describes the development of a novel microdevice for forensic DNA processing of reference swabs. This microdevice incorporates an enzyme-based assay for DNA preparation, which allows for faster processing times and reduced sample handling. Infrared-mediated PCR (IR-PCR) is used for STR amplification using a custom reaction mixture, allowing for amplification of STR loci in 45 min while circumventing the limitations of traditional block thermocyclers. Uniquely positioned valves coupled with a simple rotational platform are used to exert fluidic control, eliminating the need for bulky external equipment. All microdevices were fabricated using laser ablation and thermal bonding of PMMA layers. Using this microdevice, the enzyme-mediated DNA liberation module produced DNA yields similar to or higher than those produced using the traditional (tube-based) protocol. Initial microdevice IR-PCR experiments to test the amplification module and reaction (using Phusion Flash/SpeedSTAR) generated near-full profiles that suffered from interlocus peak imbalance and poor adenylation (significant -A). However, subsequent attempts using KAPA 2G and Pfu Ultra polymerases generated full STR profiles with improved interlocus balance and the expected adenylated product. A fully integrated run designed to test microfluidic control successfully generated CE-ready STR amplicons in less than 2 h (<1 h of hands-on time). Using this approach, high-quality STR profiles were developed that were consistent with those produced using conventional DNA purification and STR amplification methods. This method is a smaller, more elegant solution than current microdevice methods and offers a cheaper, hands-free, closed-system alternative to traditional forensic methods. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. [Application of chemometrics in composition-activity relationship research of traditional Chinese medicine].

    PubMed

    Han, Sheng-Nan

    2014-07-01

    Chemometrics is a new branch of chemistry which is widely applied to various fields of analytical chemistry. Chemometrics can use theories and methods of mathematics, statistics, computer science and other related disciplines to optimize the chemical measurement process and maximize access to acquire chemical information and other information on material systems by analyzing chemical measurement data. In recent years, traditional Chinese medicine has attracted widespread attention. In the research of traditional Chinese medicine, it has been a key problem that how to interpret the relationship between various chemical components and its efficacy, which seriously restricts the modernization of Chinese medicine. As chemometrics brings the multivariate analysis methods into the chemical research, it has been applied as an effective research tool in the composition-activity relationship research of Chinese medicine. This article reviews the applications of chemometrics methods in the composition-activity relationship research in recent years. The applications of multivariate statistical analysis methods (such as regression analysis, correlation analysis, principal component analysis, etc. ) and artificial neural network (such as back propagation artificial neural network, radical basis function neural network, support vector machine, etc. ) are summarized, including the brief fundamental principles, the research contents and the advantages and disadvantages. Finally, the existing main problems and prospects of its future researches are proposed.

  20. Toward Mixed Method Evaluations of Scientific Visualizations and Design Process as an Evaluation Tool.

    PubMed

    Jackson, Bret; Coffey, Dane; Thorson, Lauren; Schroeder, David; Ellingson, Arin M; Nuckley, David J; Keefe, Daniel F

    2012-10-01

    In this position paper we discuss successes and limitations of current evaluation strategies for scientific visualizations and argue for embracing a mixed methods strategy of evaluation. The most novel contribution of the approach that we advocate is a new emphasis on employing design processes as practiced in related fields (e.g., graphic design, illustration, architecture) as a formalized mode of evaluation for data visualizations. To motivate this position we describe a series of recent evaluations of scientific visualization interfaces and computer graphics strategies conducted within our research group. Complementing these more traditional evaluations our visualization research group also regularly employs sketching, critique, and other design methods that have been formalized over years of practice in design fields. Our experience has convinced us that these activities are invaluable, often providing much more detailed evaluative feedback about our visualization systems than that obtained via more traditional user studies and the like. We believe that if design-based evaluation methodologies (e.g., ideation, sketching, critique) can be taught and embraced within the visualization community then these may become one of the most effective future strategies for both formative and summative evaluations.

  1. Toward Mixed Method Evaluations of Scientific Visualizations and Design Process as an Evaluation Tool

    PubMed Central

    Jackson, Bret; Coffey, Dane; Thorson, Lauren; Schroeder, David; Ellingson, Arin M.; Nuckley, David J.

    2017-01-01

    In this position paper we discuss successes and limitations of current evaluation strategies for scientific visualizations and argue for embracing a mixed methods strategy of evaluation. The most novel contribution of the approach that we advocate is a new emphasis on employing design processes as practiced in related fields (e.g., graphic design, illustration, architecture) as a formalized mode of evaluation for data visualizations. To motivate this position we describe a series of recent evaluations of scientific visualization interfaces and computer graphics strategies conducted within our research group. Complementing these more traditional evaluations our visualization research group also regularly employs sketching, critique, and other design methods that have been formalized over years of practice in design fields. Our experience has convinced us that these activities are invaluable, often providing much more detailed evaluative feedback about our visualization systems than that obtained via more traditional user studies and the like. We believe that if design-based evaluation methodologies (e.g., ideation, sketching, critique) can be taught and embraced within the visualization community then these may become one of the most effective future strategies for both formative and summative evaluations. PMID:28944349

  2. Automating the training development process for mission flight operations

    NASA Technical Reports Server (NTRS)

    Scott, Carol J.

    1994-01-01

    Traditional methods of developing training do not effectively support the changing needs of operational users in a multimission environment. The Automated Training Development System (ATDS) provides advantages over conventional methods in quality, quantity, turnaround, database maintenance, and focus on individualized instruction. The Operations System Training Group at the JPL performed a six-month study to assess the potential of ATDS to automate curriculum development and to generate and maintain course materials. To begin the study, the group acquired readily available hardware and participated in a two-week training session to introduce the process. ATDS is a building activity that combines training's traditional information-gathering with a hierarchical method for interleaving the elements. The program can be described fairly simply. A comprehensive list of candidate tasks determines the content of the database; from that database, selected critical tasks dictate which competencies of skill and knowledge to include in course material for the target audience. The training developer adds pertinent planning information about each task to the database, then ATDS generates a tailored set of instructional material, based on the specific set of selection criteria. Course material consistently leads students to a prescribed level of competency.

  3. Comparison of Chemical Constituents in Scrophulariae Radix Processed by Different Methods based on UFLC-MS Combined with Multivariate Statistical Analysis.

    PubMed

    Wang, Shengnan; Hua, Yujiao; Zou, Lisi; Liu, Xunhong; Yan, Ying; Zhao, Hui; Luo, Yiyuan; Liu, Juanxiu

    2018-02-01

    Scrophulariae Radix is one of the most popular traditional Chinese medicines (TCMs). Primary processing of Scrophulariae Radix is an important link which closely related to the quality of products in this TCM. The aim of this study is to explore the influence of different processing methods on chemical constituents in Scrophulariae Radix. The difference of chemical constituents in Scrophulariae Radix processed by different methods was analyzed by using ultra fast liquid chromatography-triple quadrupole-time of flight mass spectrometry coupled with principal component analysis and orthogonal partial least squares discriminant analysis. Furthermore, the contents of 12 index differential constituents in Scrophulariae Radix processed by different methods were simultaneously determined by using ultra fast liquid chromatography coupled with triple quadrupole-linear ion trap mass spectrometry. Gray relational analysis was performed to evaluate the different processed samples according to the contents of 12 constituents. All of the results demonstrated that the quality of Scrophulariae Radix processed by "sweating" method was better. This study will provide the basic information for revealing the change law of chemical constituents in Scrophulariae Radix processed by different methods and facilitating selection of the suitable processing method of this TCM. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  4. The Impact of Social Media on Dissemination and Implementation of Clinical Practice Guidelines: A Longitudinal Observational Study.

    PubMed

    Narayanaswami, Pushpa; Gronseth, Gary; Dubinsky, Richard; Penfold-Murray, Rebecca; Cox, Julie; Bever, Christopher; Martins, Yolanda; Rheaume, Carol; Shouse, Denise; Getchius, Thomas S D

    2015-08-13

    Evidence-based clinical practice guidelines (CPGs) are statements that provide recommendations to optimize patient care for a specific clinical problem or question. Merely reading a guideline rarely leads to implementation of recommendations. The American Academy of Neurology (AAN) has a formal process of guideline development and dissemination. The last few years have seen a burgeoning of social media such as Facebook, Twitter, and LinkedIn, and newer methods of dissemination such as podcasts and webinars. The role of these media in guideline dissemination has not been studied. Systematic evaluation of dissemination methods and comparison of the effectiveness of newer methods with traditional methods is not available. It is also not known whether specific dissemination methods may be more effectively targeted to specific audiences. Our aim was to (1) develop an innovative dissemination strategy by adding social media-based dissemination methods to traditional methods for the AAN clinical practice guidelines "Complementary and alternative medicine in multiple sclerosis" ("CAM in MS") and (2) evaluate whether the addition of social media outreach improves awareness of the CPG and knowledge of CPG recommendations, and affects implementation of those recommendations. Outcomes were measured by four surveys in each of the two target populations: patients and physicians/clinicians ("physicians"). The primary outcome was the difference in participants' intent to discuss use of complementary and alternative medicine (CAM) with their physicians or patients, respectively, after novel dissemination, as compared with that after traditional dissemination. Secondary outcomes were changes in awareness of the CPG, knowledge of CPG content, and behavior regarding CAM use in multiple sclerosis (MS). Response rates were 25.08% (622/2480) for physicians and 43.5% (348/800) for patients. Awareness of the CPG increased after traditional dissemination (absolute difference, 95% confidence interval: physicians 36%, 95% CI 25-46, and patients 10%, 95% CI 1-11) but did not increase further after novel dissemination (physicians 0%, 95% CI -11 to 11, and patients -4%, 95% CI -6 to 14). Intent to discuss CAM also increased after traditional dissemination but did not change after novel dissemination (traditional: physicians 12%, 95% CI 2-22, and patients 19%, 95% CI 3-33; novel: physicians 11%, 95% CI -1 to -21, and patients -8%, 95% CI -22 to 8). Knowledge of CPG recommendations and behavior regarding CAM use in MS did not change after either traditional dissemination or novel dissemination. Social media-based dissemination methods did not confer additional benefit over print-, email-, and Internet-based methods in increasing CPG awareness and changing intent in physicians or patients. Research on audience selection, message formatting, and message delivery is required to utilize Web 2.0 technologies optimally for dissemination.

  5. Microwave-assisted routes for rapid and efficient modification of layered perovskites.

    PubMed

    Akbarian-Tefaghi, S; Wiley, J B

    2018-02-27

    Recent advances in exploiting microwave radiation in the topochemical modification of layered oxide perovskites are presented. Such methods work well for rapid bulk synthetic steps used in the production of novel inorganic-organic hybrids (protonation, grafting, intercalation, and in situ click reactions), exfoliation to produce dispersed nanosheets, and post-exfoliation processing to rapidly vary nanosheet surface groups. Compared to traditional methods that often take days, microwave methods can produce quality products in as little as 1-2 h.

  6. Achieving real-time capsule endoscopy (CE) video visualization through panoramic imaging

    NASA Astrophysics Data System (ADS)

    Yi, Steven; Xie, Jean; Mui, Peter; Leighton, Jonathan A.

    2013-02-01

    In this paper, we mainly present a novel and real-time capsule endoscopy (CE) video visualization concept based on panoramic imaging. Typical CE videos run about 8 hours and are manually reviewed by physicians to locate diseases such as bleedings and polyps. To date, there is no commercially available tool capable of providing stabilized and processed CE video that is easy to analyze in real time. The burden on physicians' disease finding efforts is thus big. In fact, since the CE camera sensor has a limited forward looking view and low image frame rate (typical 2 frames per second), and captures very close range imaging on the GI tract surface, it is no surprise that traditional visualization method based on tracking and registration often fails to work. This paper presents a novel concept for real-time CE video stabilization and display. Instead of directly working on traditional forward looking FOV (field of view) images, we work on panoramic images to bypass many problems facing traditional imaging modalities. Methods on panoramic image generation based on optical lens principle leading to real-time data visualization will be presented. In addition, non-rigid panoramic image registration methods will be discussed.

  7. Confirmation of filament dissolution behavior by analyzing electrical field effect during reset process in oxide-based RRAM

    NASA Astrophysics Data System (ADS)

    Pan, Chih-Hung; Chang, Ting-Chang; Tsai, Tsung-Ming; Chang, Kuan-Chang; Chu, Tian-Jian; Lin, Wen-Yan; Chen, Min-Chen; Sze, Simon M.

    2016-09-01

    In this letter, we demonstrate completely different characteristics with different operating modes and analyze the electrical field effect to confirm the filament dissolution behavior. The device exhibited a larger memory window when using a single voltage sweep method during reset process rather than the traditional double sweep method. The phenomenon was verified by using fast I-V measurement to simulate the two operating methods. A better high resistance state (HRS) will be obtained with a very short rising time pulse, but quite notably, lower power consumption was needed. We proposed the electrical field effect to explain the phenomenon and demonstrate distribution by COMSOL simulation.

  8. “The prayer circles in the air”: a qualitative study about traditional healer profiles and practice in Northern Norway

    PubMed Central

    Langås-Larsen, Anette; Salamonsen, Anita; Kristoffersen, Agnete Egilsdatter; Stub, Trine

    2018-01-01

    ABSTRACT In Northern Norway, traditional healing has been preserved by passing down the knowledge through generations. Religious prayers of healing (reading) and Sami rituals (curing) are examples of methods that are used. We have examined traditional healers’ understanding of traditional healing, the healing process and their own practice, as well as what characteristics healers should have. Semi-structured individual interviews and focus group interviews were conducted among 15 traditional healers in two coastal Sami municipalities in Norway. The traditional healers understood traditional healing as the initiation of the patient’s self-healing power. This power was initiated through healing rituals and explained as the power of God and placebo effect. During the healing ritual, the doctor’s medical diagnoses, the patient’s personal data and a prayer in the name of The Father, The Son and The Holy Spirit were used in combination with steel and elements from the nature. The traditional healers stated that they had to be trustworthy, calm and mentally strong. Healers who claimed that they had supernatural abilities (clairvoyant or warm hands) were regarded as extra powerful. According to the participants in this study, the healers must be trustworthy, calm and mentally strong. Moreover, these traditional healers drew on information from conventional medicine when performing their rituals. PMID:29848221

  9. [Research on whole blending end-point evaluation method of Angong Niuhuang Wan based on QbD concept].

    PubMed

    Liu, Xiao-Na; Zheng, Qiu-Sheng; Che, Xiao-Qing; Wu, Zhi-Sheng; Qiao, Yan-Jiang

    2017-03-01

    The blending end-point determination of Angong Niuhuang Wan (AGNH) is a key technology problem. The control strategy based on quality by design (QbD) concept proposes a whole blending end-point determination method, and provides a methodology for blending the Chinese materia medica containing mineral substances. Based on QbD concept, the laser induced breakdown spectroscopy (LIBS) was used to assess the cinnabar, realgar and pearl powder blending of AGNH in a pilot-scale experiment, especially the whole blending end-point in this study. The blending variability of three mineral medicines including cinnabar, realgar and pearl powder, was measured by moving window relative standard deviation (MWRSD) based on LIBS. The time profiles of realgar and pearl powder did not produce consistent results completely, but all of them reached even blending at the last blending stage, so that the whole proposal blending end point was determined. LIBS is a promising Process Analytical Technology (PAT) for process control. Unlike other elemental determination technologies such ICP-OES, LIBS does not need an elaborate digestion procedure, which is a promising and rapid technique to understand the blending process of Chinese materia medica (CMM) containing cinnabar, realgar and other mineral traditional Chinese medicine. This study proposed a novel method for the research of large varieties of traditional Chinese medicines.. Copyright© by the Chinese Pharmaceutical Association.

  10. An integral design strategy combining optical system and image processing to obtain high resolution images

    NASA Astrophysics Data System (ADS)

    Wang, Jiaoyang; Wang, Lin; Yang, Ying; Gong, Rui; Shao, Xiaopeng; Liang, Chao; Xu, Jun

    2016-05-01

    In this paper, an integral design that combines optical system with image processing is introduced to obtain high resolution images, and the performance is evaluated and demonstrated. Traditional imaging methods often separate the two technical procedures of optical system design and imaging processing, resulting in the failures in efficient cooperation between the optical and digital elements. Therefore, an innovative approach is presented to combine the merit function during optical design together with the constraint conditions of image processing algorithms. Specifically, an optical imaging system with low resolution is designed to collect the image signals which are indispensable for imaging processing, while the ultimate goal is to obtain high resolution images from the final system. In order to optimize the global performance, the optimization function of ZEMAX software is utilized and the number of optimization cycles is controlled. Then Wiener filter algorithm is adopted to process the image simulation and mean squared error (MSE) is taken as evaluation criterion. The results show that, although the optical figures of merit for the optical imaging systems is not the best, it can provide image signals that are more suitable for image processing. In conclusion. The integral design of optical system and image processing can search out the overall optimal solution which is missed by the traditional design methods. Especially, when designing some complex optical system, this integral design strategy has obvious advantages to simplify structure and reduce cost, as well as to gain high resolution images simultaneously, which has a promising perspective of industrial application.

  11. Oral anatomy laboratory examinations in a physical therapy program.

    PubMed

    Fabrizio, Philip A

    2013-01-01

    The process of creating and administering traditional tagged anatomy laboratory examinations is time consuming for instructors and limits laboratory access for students. Depending on class size and the number of class, sections, creating, administering, and breaking down a tagged laboratory examination may involve one to two eight-hour days. During the time that a tagged examination is being created, student productivity may be reduced as the anatomy laboratory is inaccessible to students. Further, the type of questions that can be asked in a tagged laboratory examination may limit student assessment to lower level cognitive abilities and may limit the instructors' ability to assess the students' understanding of anatomical and clinical concepts. Anatomy is a foundational science in the Physical Therapy curriculum and a thorough understanding of anatomy is necessary to progress through the subsequent clinical courses. Physical therapy curricula have evolved to reflect the changing role of physical therapists to primary caregivers by introducing a greater scope of clinical courses earlier in the curriculum. Physical therapy students must have a thorough understanding of clinical anatomy early in the education process. However, traditional anatomy examination methods may not be reflective of the clinical thought processes required of physical therapy students. Traditional laboratory examination methods also reduce student productivity by limiting access during examination set-up and breakdown. To provide a greater complexity of questions and reduced overall laboratory time required for examinations, the Physical Therapy Program at Mercer University has introduced oral laboratory examinations for the gross anatomy course series. © 2012 American Association of Anatomists.

  12. An automatic and effective parameter optimization method for model tuning

    NASA Astrophysics Data System (ADS)

    Zhang, T.; Li, L.; Lin, Y.; Xue, W.; Xie, F.; Xu, H.; Huang, X.

    2015-11-01

    Physical parameterizations in general circulation models (GCMs), having various uncertain parameters, greatly impact model performance and model climate sensitivity. Traditional manual and empirical tuning of these parameters is time-consuming and ineffective. In this study, a "three-step" methodology is proposed to automatically and effectively obtain the optimum combination of some key parameters in cloud and convective parameterizations according to a comprehensive objective evaluation metrics. Different from the traditional optimization methods, two extra steps, one determining the model's sensitivity to the parameters and the other choosing the optimum initial value for those sensitive parameters, are introduced before the downhill simplex method. This new method reduces the number of parameters to be tuned and accelerates the convergence of the downhill simplex method. Atmospheric GCM simulation results show that the optimum combination of these parameters determined using this method is able to improve the model's overall performance by 9 %. The proposed methodology and software framework can be easily applied to other GCMs to speed up the model development process, especially regarding unavoidable comprehensive parameter tuning during the model development stage.

  13. Determination of Carbonyl Functional Groups in Bio-oils by Potentiometric Titration: The Faix Method

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Black, Stuart; Ferrell, Jack R.

    We know that carbonyl compounds, present in bio-oils, are responsible for bio-oil property changes upon storage and during upgrading. Specifically, carbonyls cause an increase in viscosity (often referred to as 'aging') during storage of bio-oils. As such, carbonyl content has previously been used as a method of tracking bio-oil aging and condensation reactions with less variability than viscosity measurements. In addition, carbonyls are also responsible for coke formation in bio-oil upgrading processes. Given the importance of carbonyls in bio-oils, accurate analytical methods for their quantification are very important for the bio-oil community. Potentiometric titration methods based on carbonyl oximation havemore » long been used for the determination of carbonyl content in pyrolysis bio-oils. Here, we present a modification of the traditional carbonyl oximation procedures that results in less reaction time, smaller sample size, higher precision, and more accurate carbonyl determinations. And while traditional carbonyl oximation methods occur at room temperature, the Faix method presented here occurs at an elevated temperature of 80 degrees C.« less

  14. Determination of Carbonyl Functional Groups in Bio-oils by Potentiometric Titration: The Faix Method

    DOE PAGES

    Black, Stuart; Ferrell, Jack R.

    2017-02-07

    We know that carbonyl compounds, present in bio-oils, are responsible for bio-oil property changes upon storage and during upgrading. Specifically, carbonyls cause an increase in viscosity (often referred to as 'aging') during storage of bio-oils. As such, carbonyl content has previously been used as a method of tracking bio-oil aging and condensation reactions with less variability than viscosity measurements. In addition, carbonyls are also responsible for coke formation in bio-oil upgrading processes. Given the importance of carbonyls in bio-oils, accurate analytical methods for their quantification are very important for the bio-oil community. Potentiometric titration methods based on carbonyl oximation havemore » long been used for the determination of carbonyl content in pyrolysis bio-oils. Here, we present a modification of the traditional carbonyl oximation procedures that results in less reaction time, smaller sample size, higher precision, and more accurate carbonyl determinations. And while traditional carbonyl oximation methods occur at room temperature, the Faix method presented here occurs at an elevated temperature of 80 degrees C.« less

  15. An Improved Computing Method for 3D Mechanical Connectivity Rates Based on a Polyhedral Simulation Model of Discrete Fracture Network in Rock Masses

    NASA Astrophysics Data System (ADS)

    Li, Mingchao; Han, Shuai; Zhou, Sibao; Zhang, Ye

    2018-06-01

    Based on a 3D model of a discrete fracture network (DFN) in a rock mass, an improved projective method for computing the 3D mechanical connectivity rate was proposed. The Monte Carlo simulation method, 2D Poisson process and 3D geological modeling technique were integrated into a polyhedral DFN modeling approach, and the simulation results were verified by numerical tests and graphical inspection. Next, the traditional projective approach for calculating the rock mass connectivity rate was improved using the 3D DFN models by (1) using the polyhedral model to replace the Baecher disk model; (2) taking the real cross section of the rock mass, rather than a part of the cross section, as the test plane; and (3) dynamically searching the joint connectivity rates using different dip directions and dip angles at different elevations to calculate the maximum, minimum and average values of the joint connectivity at each elevation. In a case study, the improved method and traditional method were used to compute the mechanical connectivity rate of the slope of a dam abutment. The results of the two methods were further used to compute the cohesive force of the rock masses. Finally, a comparison showed that the cohesive force derived from the traditional method had a higher error, whereas the cohesive force derived from the improved method was consistent with the suggested values. According to the comparison, the effectivity and validity of the improved method were verified indirectly.

  16. The research of computer multimedia assistant in college English listening

    NASA Astrophysics Data System (ADS)

    Zhang, Qian

    2012-04-01

    With the technology development of network information, there exists more and more seriously questions to our education. Computer multimedia application breaks the traditional foreign language teaching and brings new challenges and opportunities for the education. Through the multiple media application, the teaching process is full of animation, image, voice, and characters. This can improve the learning initiative and objective with great development of learning efficiency. During the traditional foreign language teaching, people use characters learning. However, through this method, the theory performance is good but the practical application is low. During the long time computer multimedia application in the foreign language teaching, many teachers still have prejudice. Therefore, the method is not obtaining the effect. After all the above, the research has significant meaning for improving the teaching quality of foreign language.

  17. Regularized Embedded Multiple Kernel Dimensionality Reduction for Mine Signal Processing.

    PubMed

    Li, Shuang; Liu, Bing; Zhang, Chen

    2016-01-01

    Traditional multiple kernel dimensionality reduction models are generally based on graph embedding and manifold assumption. But such assumption might be invalid for some high-dimensional or sparse data due to the curse of dimensionality, which has a negative influence on the performance of multiple kernel learning. In addition, some models might be ill-posed if the rank of matrices in their objective functions was not high enough. To address these issues, we extend the traditional graph embedding framework and propose a novel regularized embedded multiple kernel dimensionality reduction method. Different from the conventional convex relaxation technique, the proposed algorithm directly takes advantage of a binary search and an alternative optimization scheme to obtain optimal solutions efficiently. The experimental results demonstrate the effectiveness of the proposed method for supervised, unsupervised, and semisupervised scenarios.

  18. Visualization techniques for tongue analysis in traditional Chinese medicine

    NASA Astrophysics Data System (ADS)

    Pham, Binh L.; Cai, Yang

    2004-05-01

    Visual inspection of the tongue has been an important diagnostic method of Traditional Chinese Medicine (TCM). Clinic data have shown significant connections between various viscera cancers and abnormalities in the tongue and the tongue coating. Visual inspection of the tongue is simple and inexpensive, but the current practice in TCM is mainly experience-based and the quality of the visual inspection varies between individuals. The computerized inspection method provides quantitative models to evaluate color, texture and surface features on the tongue. In this paper, we investigate visualization techniques and processes to allow interactive data analysis with the aim to merge computerized measurements with human expert's diagnostic variables based on five-scale diagnostic conditions: Healthy (H), History Cancers (HC), History of Polyps (HP), Polyps (P) and Colon Cancer (C).

  19. Big data mining analysis method based on cloud computing

    NASA Astrophysics Data System (ADS)

    Cai, Qing Qiu; Cui, Hong Gang; Tang, Hao

    2017-08-01

    Information explosion era, large data super-large, discrete and non-(semi) structured features have gone far beyond the traditional data management can carry the scope of the way. With the arrival of the cloud computing era, cloud computing provides a new technical way to analyze the massive data mining, which can effectively solve the problem that the traditional data mining method cannot adapt to massive data mining. This paper introduces the meaning and characteristics of cloud computing, analyzes the advantages of using cloud computing technology to realize data mining, designs the mining algorithm of association rules based on MapReduce parallel processing architecture, and carries out the experimental verification. The algorithm of parallel association rule mining based on cloud computing platform can greatly improve the execution speed of data mining.

  20. Orthorectification by Using Gpgpu Method

    NASA Astrophysics Data System (ADS)

    Sahin, H.; Kulur, S.

    2012-07-01

    Thanks to the nature of the graphics processing, the newly released products offer highly parallel processing units with high-memory bandwidth and computational power of more than teraflops per second. The modern GPUs are not only powerful graphic engines but also they are high level parallel programmable processors with very fast computing capabilities and high-memory bandwidth speed compared to central processing units (CPU). Data-parallel computations can be shortly described as mapping data elements to parallel processing threads. The rapid development of GPUs programmability and capabilities attracted the attentions of researchers dealing with complex problems which need high level calculations. This interest has revealed the concepts of "General Purpose Computation on Graphics Processing Units (GPGPU)" and "stream processing". The graphic processors are powerful hardware which is really cheap and affordable. So the graphic processors became an alternative to computer processors. The graphic chips which were standard application hardware have been transformed into modern, powerful and programmable processors to meet the overall needs. Especially in recent years, the phenomenon of the usage of graphics processing units in general purpose computation has led the researchers and developers to this point. The biggest problem is that the graphics processing units use different programming models unlike current programming methods. Therefore, an efficient GPU programming requires re-coding of the current program algorithm by considering the limitations and the structure of the graphics hardware. Currently, multi-core processors can not be programmed by using traditional programming methods. Event procedure programming method can not be used for programming the multi-core processors. GPUs are especially effective in finding solution for repetition of the computing steps for many data elements when high accuracy is needed. Thus, it provides the computing process more quickly and accurately. Compared to the GPUs, CPUs which perform just one computing in a time according to the flow control are slower in performance. This structure can be evaluated for various applications of computer technology. In this study covers how general purpose parallel programming and computational power of the GPUs can be used in photogrammetric applications especially direct georeferencing. The direct georeferencing algorithm is coded by using GPGPU method and CUDA (Compute Unified Device Architecture) programming language. Results provided by this method were compared with the traditional CPU programming. In the other application the projective rectification is coded by using GPGPU method and CUDA programming language. Sample images of various sizes, as compared to the results of the program were evaluated. GPGPU method can be used especially in repetition of same computations on highly dense data, thus finding the solution quickly.

  1. A novel scalable manufacturing process for the production of hydrogel-forming microneedle arrays.

    PubMed

    Lutton, Rebecca E M; Larrañeta, Eneko; Kearney, Mary-Carmel; Boyd, Peter; Woolfson, A David; Donnelly, Ryan F

    2015-10-15

    A novel manufacturing process for fabricating microneedle arrays (MN) has been designed and evaluated. The prototype is able to successfully produce 14×14 MN arrays and is easily capable of scale-up, enabling the transition from laboratory to industry and subsequent commercialisation. The method requires the custom design of metal MN master templates to produce silicone MN moulds using an injection moulding process. The MN arrays produced using this novel method was compared with centrifugation, the traditional method of producing aqueous hydrogel-forming MN arrays. The results proved that there was negligible difference between either methods, with each producing MN arrays with comparable quality. Both types of MN arrays can be successfully inserted in a skin simulant. In both cases the insertion depth was approximately 60% of the needle length and the height reduction after insertion was in both cases approximately 3%. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. Adaptive interference cancel filter for evoked potential using high-order cumulants.

    PubMed

    Lin, Bor-Shyh; Lin, Bor-Shing; Chong, Fok-Ching; Lai, Feipei

    2004-01-01

    This paper is to present evoked potential (EP) processing using adaptive interference cancel (AIC) filter with second and high order cumulants. In conventional ensemble averaging method, people have to conduct repetitively experiments to record the required data. Recently, the use of AIC structure with second statistics in processing EP has proved more efficiency than traditional averaging method, but it is sensitive to both of the reference signal statistics and the choice of step size. Thus, we proposed higher order statistics-based AIC method to improve these disadvantages. This study was experimented in somatosensory EP corrupted with EEG. Gradient type algorithm is used in AIC method. Comparisons with AIC filter on second, third, fourth order statistics are also presented in this paper. We observed that AIC filter with third order statistics has better convergent performance for EP processing and is not sensitive to the selection of step size and reference input.

  3. A novel scalable manufacturing process for the production of hydrogel-forming microneedle arrays

    PubMed Central

    Lutton, Rebecca E.M.; Larrañeta, Eneko; Kearney, Mary-Carmel; Boyd, Peter; Woolfson, A.David; Donnelly, Ryan F.

    2015-01-01

    A novel manufacturing process for fabricating microneedle arrays (MN) has been designed and evaluated. The prototype is able to successfully produce 14 × 14 MN arrays and is easily capable of scale-up, enabling the transition from laboratory to industry and subsequent commercialisation. The method requires the custom design of metal MN master templates to produce silicone MN moulds using an injection moulding process. The MN arrays produced using this novel method was compared with centrifugation, the traditional method of producing aqueous hydrogel-forming MN arrays. The results proved that there was negligible difference between either methods, with each producing MN arrays with comparable quality. Both types of MN arrays can be successfully inserted in a skin simulant. In both cases the insertion depth was approximately 60% of the needle length and the height reduction after insertion was in both cases approximately 3%. PMID:26302858

  4. An expert system for natural language processing

    NASA Technical Reports Server (NTRS)

    Hennessy, John F.

    1988-01-01

    A solution to the natural language processing problem that uses a rule based system, written in OPS5, to replace the traditional parsing method is proposed. The advantage to using a rule based system are explored. Specifically, the extensibility of a rule based solution is discussed as well as the value of maintaining rules that function independently. Finally, the power of using semantics to supplement the syntactic analysis of a sentence is considered.

  5. Recherche Empirique sur les Processes de reequilibrage de l'attention dans le traitement des problemes educatifs. (Empirical Study on the Process of Redirecting Attention in Educational Problem-Solving.)

    ERIC Educational Resources Information Center

    Wasserstein-Warnet, Marc M.

    2000-01-01

    Asserts that traditional strategies of problem-solving are inadequate and that a new method is needed. Suggests four ways to redirect attention in problem solving: overcoming an instant or linear perception of time, interacting between the problem's components and its whole, searching for the meaning or sense of a problem, and studying the…

  6. Investigation of KDP crystal surface based on an improved bidimensional empirical mode decomposition method

    NASA Astrophysics Data System (ADS)

    Lu, Lei; Yan, Jihong; Chen, Wanqun; An, Shi

    2018-03-01

    This paper proposed a novel spatial frequency analysis method for the investigation of potassium dihydrogen phosphate (KDP) crystal surface based on an improved bidimensional empirical mode decomposition (BEMD) method. Aiming to eliminate end effects of the BEMD method and improve the intrinsic mode functions (IMFs) for the efficient identification of texture features, a denoising process was embedded in the sifting iteration of BEMD method. With removing redundant information in decomposed sub-components of KDP crystal surface, middle spatial frequencies of the cutting and feeding processes were identified. Comparative study with the power spectral density method, two-dimensional wavelet transform (2D-WT), as well as the traditional BEMD method, demonstrated that the method developed in this paper can efficiently extract texture features and reveal gradient development of KDP crystal surface. Furthermore, the proposed method was a self-adaptive data driven technique without prior knowledge, which overcame shortcomings of the 2D-WT model such as the parameters selection. Additionally, the proposed method was a promising tool for the application of online monitoring and optimal control of precision machining process.

  7. Identification of modal parameters including unmeasured forces and transient effects

    NASA Astrophysics Data System (ADS)

    Cauberghe, B.; Guillaume, P.; Verboven, P.; Parloo, E.

    2003-08-01

    In this paper, a frequency-domain method to estimate modal parameters from short data records with known input (measured) forces and unknown input forces is presented. The method can be used for an experimental modal analysis, an operational modal analysis (output-only data) and the combination of both. A traditional experimental and operational modal analysis in the frequency domain starts respectively, from frequency response functions and spectral density functions. To estimate these functions accurately sufficient data have to be available. The technique developed in this paper estimates the modal parameters directly from the Fourier spectra of the outputs and the known input. Instead of using Hanning windows on these short data records the transient effects are estimated simultaneously with the modal parameters. The method is illustrated, tested and validated by Monte Carlo simulations and experiments. The presented method to process short data sequences leads to unbiased estimates with a small variance in comparison to the more traditional approaches.

  8. A new direct growth method of graphene on Si-face of 6H-SiC by synergy of the inner and external carbon sources

    NASA Astrophysics Data System (ADS)

    Yang, Zhiyuan; Xu, Shicai; Zhao, Lili; Zhang, Jing; Wang, Zhengping; Chen, Xiufang; Cheng, Xiufeng; Yu, Fapeng; Zhao, Xian

    2018-04-01

    Graphene is a promising two-dimensional material that has possible application in various disciplines, due to its super properties, including high carrier mobility, chemical stability, and optical transparency etc. In this paper, we report an inner and external carbon synergy (IECS) method to grow graphene on Si-face of 6H-SiC. This method combined the advantages of chemical vapor deposition (CVD) and traditional epitaxial growth (EG) based on silicon carbide, which providing a feasible approach for growing graphene on the SiC substrates. The graphene was synthesized within just 3 min, which was more than one order of magnitude faster than the graphene grown on 6H-SiC substrates by the traditional EG method. The growth temperature was ∼200 °C lower than the EG process. The directly grown graphene maintained the compatibility with the semiconductor technique, which is benefit for use in graphene-based microelectronic devices.

  9. An automatic and effective parameter optimization method for model tuning

    NASA Astrophysics Data System (ADS)

    Zhang, T.; Li, L.; Lin, Y.; Xue, W.; Xie, F.; Xu, H.; Huang, X.

    2015-05-01

    Physical parameterizations in General Circulation Models (GCMs), having various uncertain parameters, greatly impact model performance and model climate sensitivity. Traditional manual and empirical tuning of these parameters is time consuming and ineffective. In this study, a "three-step" methodology is proposed to automatically and effectively obtain the optimum combination of some key parameters in cloud and convective parameterizations according to a comprehensive objective evaluation metrics. Different from the traditional optimization methods, two extra steps, one determines parameter sensitivity and the other chooses the optimum initial value of sensitive parameters, are introduced before the downhill simplex method to reduce the computational cost and improve the tuning performance. Atmospheric GCM simulation results show that the optimum combination of these parameters determined using this method is able to improve the model's overall performance by 9%. The proposed methodology and software framework can be easily applied to other GCMs to speed up the model development process, especially regarding unavoidable comprehensive parameters tuning during the model development stage.

  10. Performance analysis of a Principal Component Analysis ensemble classifier for Emotiv headset P300 spellers.

    PubMed

    Elsawy, Amr S; Eldawlatly, Seif; Taher, Mohamed; Aly, Gamal M

    2014-01-01

    The current trend to use Brain-Computer Interfaces (BCIs) with mobile devices mandates the development of efficient EEG data processing methods. In this paper, we demonstrate the performance of a Principal Component Analysis (PCA) ensemble classifier for P300-based spellers. We recorded EEG data from multiple subjects using the Emotiv neuroheadset in the context of a classical oddball P300 speller paradigm. We compare the performance of the proposed ensemble classifier to the performance of traditional feature extraction and classifier methods. Our results demonstrate the capability of the PCA ensemble classifier to classify P300 data recorded using the Emotiv neuroheadset with an average accuracy of 86.29% on cross-validation data. In addition, offline testing of the recorded data reveals an average classification accuracy of 73.3% that is significantly higher than that achieved using traditional methods. Finally, we demonstrate the effect of the parameters of the P300 speller paradigm on the performance of the method.

  11. Conventional and dense gas techniques for the production of liposomes: a review.

    PubMed

    Meure, Louise A; Foster, Neil R; Dehghani, Fariba

    2008-01-01

    The aim of this review paper is to compare the potential of various techniques developed for production of homogenous, stable liposomes. Traditional techniques, such as Bangham, detergent depletion, ether/ethanol injection, reverse-phase evaporation and emulsion methods, were compared with the recent advanced techniques developed for liposome formation. The major hurdles for scaling up the traditional methods are the consumption of large quantities of volatile organic solvent, the stability and homogeneity of the liposomal product, as well as the lengthy multiple steps involved. The new methods have been designed to alleviate the current issues for liposome formulation. Dense gas liposome techniques are still in their infancy, however they have remarkable advantages in reducing the use of organic solvents, providing fast, single-stage production and producing stable, uniform liposomes. Techniques such as the membrane contactor and heating methods are also promising as they eliminate the use of organic solvent, however high temperature is still required for processing.

  12. [Technical efficiency of traditional hospitals and public enterprises in Andalusia (Spain)].

    PubMed

    Herrero Tabanera, Luis; Martín Martín, José Jesús; López del Amo González, Ma del Puerto

    2015-01-01

    To assess the technical efficiency of traditional public hospitals without their own legal identity and subject to administrative law, and that of public enterprise hospitals, with their own legal identities and partly governed by private law, all of them belonging to the taxypayer-funded health system of Andalusia during the period 2005 -2008. The study included the 32 publicly-owned hospitals in Andalusia during the period 2005-2008. The method consisted of two stages. In the first stage, the indices of technical efficiency of the hospitals were calculated using Data Envelopment Analysis, and the change in total factor productivity was estimated using the Malmquist index. The results were compared according to perceived quality, and a sensitivity analysis was conducted through an auxiliary model and bootstrapping. In the second stage, a bivariate analysis was performed between hospital efficiency and organization type. Public enterprises were more efficient than traditional hospitals (on average by over 10%) in each of the study years. Nevertheless, a process of convergence was observed between the two types of organizations because, while the efficiency of traditional hospitals increased slightly (by 0.50%) over the study period, the performance of public enterprises declined by over 2%. The possible reasons for the greater efficiency of public enterprises include their greater budgetary and employment flexibility. However, the convergence process observed points to a process of mutual learning that is not necessarily efficient. Copyright © 2014 SESPAS. Published by Elsevier Espana. All rights reserved.

  13. Niobium superconducting rf cavity fabrication by electrohydraulic forming

    NASA Astrophysics Data System (ADS)

    Cantergiani, E.; Atieh, S.; Léaux, F.; Perez Fontenla, A. T.; Prunet, S.; Dufay-Chanat, L.; Koettig, T.; Bertinelli, F.; Capatina, O.; Favre, G.; Gerigk, F.; Jeanson, A. C.; Fuzeau, J.; Avrillaud, G.; Alleman, D.; Bonafe, J.; Marty, P.

    2016-11-01

    Superconducting rf (SRF) cavities are traditionally fabricated from superconducting material sheets or made of copper coated with superconducting material, followed by trim machining and electron-beam welding. An alternative technique to traditional shaping methods, such as deep-drawing and spinning, is electrohydraulic forming (EHF). In EHF, half-cells are obtained through ultrahigh-speed deformation of blank sheets, using shockwaves induced in water by a pulsed electrical discharge. With respect to traditional methods, such a highly dynamic process can yield interesting results in terms of effectiveness, repeatability, final shape precision, higher formability, and reduced springback. In this paper, the first results of EHF on high purity niobium are presented and discussed. The simulations performed in order to master the multiphysics phenomena of EHF and to adjust its process parameters are presented. The microstructures of niobium half-cells produced by EHF and by spinning have been compared in terms of damage created in the material during the forming operation. The damage was assessed through hardness measurements, residual resistivity ratio (RRR) measurements, and electron backscattered diffraction analyses. It was found that EHF does not worsen the damage of the material during forming and instead, some areas of the half-cell have shown lower damage compared to spinning. Moreover, EHF is particularly advantageous to reduce the forming time, preserve roughness, and to meet the final required shape accuracy.

  14. A web-based knowledge management system integrating Western and Traditional Chinese Medicine for relational medical diagnosis.

    PubMed

    Herrera-Hernandez, Maria C; Lai-Yuen, Susana K; Piegl, Les A; Zhang, Xiao

    2016-10-26

    This article presents the design of a web-based knowledge management system as a training and research tool for the exploration of key relationships between Western and Traditional Chinese Medicine, in order to facilitate relational medical diagnosis integrating these mainstream healing modalities. The main goal of this system is to facilitate decision-making processes, while developing skills and creating new medical knowledge. Traditional Chinese Medicine can be considered as an ancient relational knowledge-based approach, focusing on balancing interrelated human functions to reach a healthy state. Western Medicine focuses on specialties and body systems and has achieved advanced methods to evaluate the impact of a health disorder on the body functions. Identifying key relationships between Traditional Chinese and Western Medicine opens new approaches for health care practices and can increase the understanding of human medical conditions. Our knowledge management system was designed from initial datasets of symptoms, known diagnosis and treatments, collected from both medicines. The datasets were subjected to process-oriented analysis, hierarchical knowledge representation and relational database interconnection. Web technology was implemented to develop a user-friendly interface, for easy navigation, training and research. Our system was prototyped with a case study on chronic prostatitis. This trial presented the system's capability for users to learn the correlation approach, connecting knowledge in Western and Traditional Chinese Medicine by querying the database, mapping validated medical information, accessing complementary information from official sites, and creating new knowledge as part of the learning process. By addressing the challenging tasks of data acquisition and modeling, organization, storage and transfer, the proposed web-based knowledge management system is presented as a tool for users in medical training and research to explore, learn and update relational information for the practice of integrated medical diagnosis. This proposal in education has the potential to enable further creation of medical knowledge from both Traditional Chinese and Western Medicine for improved care providing. The presented system positively improves the information visualization, learning process and knowledge sharing, for training and development of new skills for diagnosis and treatment, and a better understanding of medical diseases. © IMechE 2016.

  15. Comparison of ultrasound-assisted and traditional caustic leaching of spent cathode carbon (SCC) from aluminum electrolysis.

    PubMed

    Xiao, Jin; Yuan, Jie; Tian, Zhongliang; Yang, Kai; Yao, Zhen; Yu, Bailie; Zhang, Liuyun

    2018-01-01

    The spent cathode carbon (SCC) from aluminum electrolysis was subjected to caustic leaching to investigate the different effects of ultrasound-assisted and traditional methods on element fluorine (F) leaching rate and leaching residue carbon content. Sodium hydroxide (NaOH) dissolved in deionized water was used as the reaction system. Through single-factor experiments and a comparison of two leaching techniques, the optimum F leaching rate and residue carbon content for ultrasound-assisted leaching process were obtained at a temperature of 70°C, residue time of 40min, initial mass ratio of alkali to SCC (initial alkali-to-material ratio) of 0.6, liquid-to-solid ratio of 10mL/g, and ultrasonic power of 400W, respectively. Under the optimal conditions, the leaching residue carbon content was 94.72%, 2.19% larger than the carbon content of traditional leaching residue. Leaching wastewater was treated with calcium chloride (CaCl 2 ) and bleaching powder and the treated wastewater was recycled caustic solution. All in all, benefiting from advantage of the ultrasonication effects, ultrasound-assisted caustic leaching on spent cathode carbon had 55.6% shorter residue time than the traditional process with a higher impurity removal rate. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. [Establishment and practice of traditional Chinese medicine property cognitive model based on three elements].

    PubMed

    Zhang, Bing; Jin, Rui; Huang, Jianmei; Liu, Xiaoqing; Xue, Chunmiao; Lin, Zhijian

    2012-08-01

    Traditional Chinese medicine (TCM) property theory is believed to be a key and difficult point of basic theory studies of TCM. Complex concepts, components and characteristics of TCM property have long puzzled researchers and urged them to develop new angles and approaches. In the view of cognitive science, TCM property theory is a cognitive process of storing, extracting, rebuilding and summarizing the sensory information about TCMs and their effects during the medical practice struggling against diseases under the guidance of traditional Chinese philosophical thinking. The cognitive process of TCM property has particular cognitive elements and strategies. Taking into account clinical application characteristics of TCMs, this study defines the particular cognitive elements. In the combination of research methods of modern chemistry, biology and mathematics, and on the basis early-stage work for five years, we have built a TCM property cognition model based on three elements and practiced with drugs with pungent and hot properties as example, in the hope of interpreting TCM properties with modern science and providing thoughts for the nature of medical properties and instruction for rational clinical prescription.

  17. A Novel Method for Electroplating Ultra-High-Strength Glassy Metals

    NASA Technical Reports Server (NTRS)

    Ramsey, Brian; Engelhaupt, Darell; Six, N. Frank (Technical Monitor)

    2002-01-01

    A novel method for electroplating ultra-high-strength glassy metals, nickel-phosphorous and nickel-cobalt-phosphorous, has been developed at NASA Marshall Space Flight Center, cooperatively with the University of Alabama in Huntsville. Traditionally, thin coatings of these metals are achieved via electroless deposition. Benefits of the new electrolytic process include thick, low-stress deposits, free standing shapes, lower plating temperature, low maintenance, and safer operation with substantially lower cost.

  18. Comparison of automatic denoising methods for phonocardiograms with extraction of signal parameters via the Hilbert Transform

    NASA Astrophysics Data System (ADS)

    Messer, Sheila R.; Agzarian, John; Abbott, Derek

    2001-05-01

    Phonocardiograms (PCGs) have many advantages over traditional auscultation (listening to the heart) because they may be replayed, may be analyzed for spectral and frequency content, and frequencies inaudible to the human ear may be recorded. However, various sources of noise may pollute a PCG including lung sounds, environmental noise and noise generated from contact between the recording device and the skin. Because PCG signals are known to be nonlinear and it is often not possible to determine their noise content, traditional de-noising methods may not be effectively applied. However, other methods including wavelet de-noising, wavelet packet de-noising and averaging can be employed to de-noise the PCG. This study examines and compares these de-noising methods. This study answers such questions as to which de-noising method gives a better SNR, the magnitude of signal information that is lost as a result of the de-noising process, the appropriate uses of the different methods down to such specifics as to which wavelets and decomposition levels give best results in wavelet and wavelet packet de-noising. In general, the wavelet and wavelet packet de-noising performed roughly equally with optimal de-noising occurring at 3-5 levels of decomposition. Averaging also proved a highly useful de- noising technique; however, in some cases averaging is not appropriate. The Hilbert Transform is used to illustrate the results of the de-noising process and to extract instantaneous features including instantaneous amplitude, frequency, and phase.

  19. Wavelet Filter Banks for Super-Resolution SAR Imaging

    NASA Technical Reports Server (NTRS)

    Sheybani, Ehsan O.; Deshpande, Manohar; Memarsadeghi, Nargess

    2011-01-01

    This paper discusses Innovative wavelet-based filter banks designed to enhance the analysis of super resolution Synthetic Aperture Radar (SAR) images using parametric spectral methods and signal classification algorithms, SAR finds applications In many of NASA's earth science fields such as deformation, ecosystem structure, and dynamics of Ice, snow and cold land processes, and surface water and ocean topography. Traditionally, standard methods such as Fast-Fourier Transform (FFT) and Inverse Fast-Fourier Transform (IFFT) have been used to extract Images from SAR radar data, Due to non-parametric features of these methods and their resolution limitations and observation time dependence, use of spectral estimation and signal pre- and post-processing techniques based on wavelets to process SAR radar data has been proposed. Multi-resolution wavelet transforms and advanced spectral estimation techniques have proven to offer efficient solutions to this problem.

  20. The role of strategies in motor learning

    PubMed Central

    Taylor, Jordan A.; Ivry, Richard B.

    2015-01-01

    There has been renewed interest in the role of strategies in sensorimotor learning. The combination of new behavioral methods and computational methods has begun to unravel the interaction between processes related to strategic control and processes related to motor adaptation. These processes may operate on very different error signals. Strategy learning is sensitive to goal-based performance error. In contrast, adaptation is sensitive to prediction errors between the desired and actual consequences of a planned movement. The former guides what the desired movement should be, whereas the latter guides how to implement the desired movement. Whereas traditional approaches have favored serial models in which an initial strategy-based phase gives way to more automatized forms of control, it now seems that strategic and adaptive processes operate with considerable independence throughout learning, although the relative weight given the two processes will shift with changes in performance. As such, skill acquisition involves the synergistic engagement of strategic and adaptive processes. PMID:22329960

  1. A Science and Risk-Based Pragmatic Methodology for Blend and Content Uniformity Assessment.

    PubMed

    Sayeed-Desta, Naheed; Pazhayattil, Ajay Babu; Collins, Jordan; Doshi, Chetan

    2018-04-01

    This paper describes a pragmatic approach that can be applied in assessing powder blend and unit dosage uniformity of solid dose products at Process Design, Process Performance Qualification, and Continued/Ongoing Process Verification stages of the Process Validation lifecycle. The statistically based sampling, testing, and assessment plan was developed due to the withdrawal of the FDA draft guidance for industry "Powder Blends and Finished Dosage Units-Stratified In-Process Dosage Unit Sampling and Assessment." This paper compares the proposed Grouped Area Variance Estimate (GAVE) method with an alternate approach outlining the practicality and statistical rationalization using traditional sampling and analytical methods. The approach is designed to fit solid dose processes assuring high statistical confidence in both powder blend uniformity and dosage unit uniformity during all three stages of the lifecycle complying with ASTM standards as recommended by the US FDA.

  2. Teaching to Strengths: Engaging Young Boys in Learning

    ERIC Educational Resources Information Center

    Johnson, Cynthia; Gooliaff, Shauna

    2013-01-01

    Traditional teaching methods often fail to engage male students in learning. The purpose of this research was to increase student engagement in the story writing process and increase self-confidence in boys at risk. A qualitative approach included student surveys as well as teacher journaling and portfolios (including e-portfolios). The student…

  3. Computer Aided Phenomenography: The Role of Leximancer Computer Software in Phenomenographic Investigation

    ERIC Educational Resources Information Center

    Penn-Edwards, Sorrel

    2010-01-01

    The qualitative research methodology of phenomenography has traditionally required a manual sorting and analysis of interview data. In this paper I explore a potential means of streamlining this procedure by considering a computer aided process not previously reported upon. Two methods of lexicological analysis, manual and automatic, were examined…

  4. Utilization of pyrosequencing to monitor the microbiome dynamics of probiotic treated poultry (Gallus gallus domesticus) during downstream poultry processing

    USDA-ARS?s Scientific Manuscript database

    Antibiotic growth promoters that have been historically employed to control pathogens and increase the rate of animal development for human consumption are currently banned in many countries. Probiotics have been proposed as an alternative to control pathogenic bacteria. Traditional culture method...

  5. Beyond the Google Search Bar: Evaluating Source Credibility in Contemporary Research

    ERIC Educational Resources Information Center

    Sorenson, Mary E.

    2016-01-01

    Courses: Research Methods, Public Speaking, Communication Theory, any other course that requires college students to engage in a formal research process. Can be conducted in traditional, online, or hybrid courses. Objectives: In this original single-class activity, students will be able to evaluate source credibility for resources that extend…

  6. Who Needs Lewis Structures to Get VSEPR Geometries?

    ERIC Educational Resources Information Center

    Lindmark, Alan F.

    2010-01-01

    Teaching the VSEPR (valence shell electron-pair repulsion) model can be a tedious process. Traditionally, Lewis structures are drawn and the number of "electron clouds" (groups) around the central atom are counted and related to the standard VSEPR table of possible geometries. A simpler method to deduce the VSEPR structure without first drawing…

  7. Bridging the School-Home Divide in the Middle Grades: A Process for Strengthening School-Family Partnerships

    ERIC Educational Resources Information Center

    Kyzar, Kathleen; Jimerson, Jo Beth

    2018-01-01

    Evidence around adolescent learning and development is clear: School-family partnerships matter. However, traditional methods for engaging families that narrowly define who is involved and what constitutes involvement fall short of promoting optimal outcomes. Meaningful family engagement practices involve reciprocal, two-way interactions between…

  8. Critical Perspectives of Pedagogical Approaches to Reversing the Order of Integration in Double Integrals

    ERIC Educational Resources Information Center

    Tisdell, Christopher C.

    2017-01-01

    This paper presents some critical perspectives regarding pedagogical approaches to the method of reversing the order of integration in double integrals from prevailing educational literature on multivariable calculus. First, we question the message found in popular textbooks that the traditional process of reversing the order of integration is…

  9. The Process and Product: Crafting Community Portraits with Young People in Flexible Learning Settings

    ERIC Educational Resources Information Center

    Baker, Alison M.

    2016-01-01

    Community-based alternative education is situated on the margins in relation to mainstream education. Young people attending these learning sites are often characterised as "disengaged learners", who have fallen through the cracks of the traditional schooling system. The aim of this project was to use participatory visual methods with…

  10. Information and Communication Technology in the International Business Classroom: Comparing Faculty and Student Perspectives

    ERIC Educational Resources Information Center

    Van Deusen, Cheryl A.; Jones, Gordon; Mueller, Carolyn B.; Ricks, David A.; Schlegelmilch, Bodo B.

    2004-01-01

    The use of information and communication technology (ICT) is revolutionizing traditional educational methods in university contexts and changing the process of how educators do their jobs. However, research offers conflicting views regarding the benefits of ICT in the classroom. To better understand the various advantages and disadvantages of…

  11. TESTING SOLIDS SETTING APPARATUSES FOR DESIGN AND OPERATION OF WET-WEATHER FLOW SOLIDS-LIQUID SEPARATION PROCESSES

    EPA Science Inventory

    This study was a side-by-side comparison of two settling evaluation methods: one traditional and one new. The project investigated whether these column tests were capable of capturing or representing the rapidly settling particles present in wet-weather flows (WWF). The report r...

  12. Conceptual design of flapping-wing micro air vehicles.

    PubMed

    Whitney, J P; Wood, R J

    2012-09-01

    Traditional micro air vehicles (MAVs) are miniature versions of full-scale aircraft from which their design principles closely follow. The first step in aircraft design is the development of a conceptual design, where basic specifications and vehicle size are established. Conceptual design methods do not rely on specific knowledge of the propulsion system, vehicle layout and subsystems; these details are addressed later in the design process. Non-traditional MAV designs based on birds or insects are less common and without well-established conceptual design methods. This paper presents a conceptual design process for hovering flapping-wing vehicles. An energy-based accounting of propulsion and aerodynamics is combined with a one degree-of-freedom dynamic flapping model. Important results include simple analytical expressions for flight endurance and range, predictions for maximum feasible wing size and body mass, and critical design space restrictions resulting from finite wing inertia. A new figure-of-merit for wing structural-inertial efficiency is proposed and used to quantify the performance of real and artificial insect wings. The impact of these results on future flapping-wing MAV designs is discussed in detail.

  13. Solvent replacement for green processing.

    PubMed Central

    Sherman, J; Chin, B; Huibers, P D; Garcia-Valls, R; Hatton, T A

    1998-01-01

    The implementation of the Montreal Protocol, the Clean Air Act, and the Pollution Prevention Act of 1990 has resulted in increased awareness of organic solvent use in chemical processing. The advances made in the search to find "green" replacements for traditional solvents are reviewed, with reference to solvent alternatives for cleaning, coatings, and chemical reaction and separation processes. The development of solvent databases and computational methods that aid in the selection and/or design of feasible or optimal environmentally benign solvent alternatives for specific applications is also discussed. Images Figure 2 Figure 3 PMID:9539018

  14. Model-Based Verification and Validation of the SMAP Uplink Processes

    NASA Technical Reports Server (NTRS)

    Khan, M. Omair; Dubos, Gregory F.; Tirona, Joseph; Standley, Shaun

    2013-01-01

    This case study stands as an example of how a project can validate a system-level design earlier in the project life cycle than traditional V&V processes by using simulation on a system model. Specifically, this paper describes how simulation was added to a system model of the Soil Moisture Active-Passive (SMAP) mission's uplink process.Also discussed are the advantages and disadvantages of the methods employed and the lessons learned; which are intended to benefit future model-based and simulation-based V&V development efforts.

  15. GAPscreener: an automatic tool for screening human genetic association literature in PubMed using the support vector machine technique.

    PubMed

    Yu, Wei; Clyne, Melinda; Dolan, Siobhan M; Yesupriya, Ajay; Wulf, Anja; Liu, Tiebin; Khoury, Muin J; Gwinn, Marta

    2008-04-22

    Synthesis of data from published human genetic association studies is a critical step in the translation of human genome discoveries into health applications. Although genetic association studies account for a substantial proportion of the abstracts in PubMed, identifying them with standard queries is not always accurate or efficient. Further automating the literature-screening process can reduce the burden of a labor-intensive and time-consuming traditional literature search. The Support Vector Machine (SVM), a well-established machine learning technique, has been successful in classifying text, including biomedical literature. The GAPscreener, a free SVM-based software tool, can be used to assist in screening PubMed abstracts for human genetic association studies. The data source for this research was the HuGE Navigator, formerly known as the HuGE Pub Lit database. Weighted SVM feature selection based on a keyword list obtained by the two-way z score method demonstrated the best screening performance, achieving 97.5% recall, 98.3% specificity and 31.9% precision in performance testing. Compared with the traditional screening process based on a complex PubMed query, the SVM tool reduced by about 90% the number of abstracts requiring individual review by the database curator. The tool also ascertained 47 articles that were missed by the traditional literature screening process during the 4-week test period. We examined the literature on genetic associations with preterm birth as an example. Compared with the traditional, manual process, the GAPscreener both reduced effort and improved accuracy. GAPscreener is the first free SVM-based application available for screening the human genetic association literature in PubMed with high recall and specificity. The user-friendly graphical user interface makes this a practical, stand-alone application. The software can be downloaded at no charge.

  16. Two-and-a-half-year-olds succeed at a traditional false-belief task with reduced processing demands.

    PubMed

    Setoh, Peipei; Scott, Rose M; Baillargeon, Renée

    2016-11-22

    When tested with traditional false-belief tasks, which require answering a standard question about the likely behavior of an agent with a false belief, children perform below chance until age 4 y or later. When tested without such questions, however, children give evidence of false-belief understanding much earlier. Are traditional tasks difficult because they tap a more advanced form of false-belief understanding (fundamental-change view) or because they impose greater processing demands (processing-demands view)? Evidence that young children succeed at traditional false-belief tasks when processing demands are reduced would support the latter view. In prior research, reductions in inhibitory-control demands led to improvements in young children's performance, but often only to chance (instead of below-chance) levels. Here we examined whether further reductions in processing demands might lead to success. We speculated that: (i) young children could respond randomly in a traditional low-inhibition task because their limited information-processing resources are overwhelmed by the total concurrent processing demands in the task; and (ii) these demands include those from the response-generation process activated by the standard question. This analysis suggested that 2.5-y-old toddlers might succeed at a traditional low-inhibition task if response-generation demands were also reduced via practice trials. As predicted, toddlers performed above chance following two response-generation practice trials; toddlers failed when these trials either were rendered less effective or were used in a high-inhibition task. These results support the processing-demands view: Even toddlers succeed at a traditional false-belief task when overall processing demands are reduced.

  17. A New Test Method of Circuit Breaker Spring Telescopic Characteristics Based Image Processing

    NASA Astrophysics Data System (ADS)

    Huang, Huimin; Wang, Feifeng; Lu, Yufeng; Xia, Xiaofei; Su, Yi

    2018-06-01

    This paper applied computer vision technology to the fatigue condition monitoring of springs, and a new telescopic characteristics test method is proposed for circuit breaker operating mechanism spring based on image processing technology. High-speed camera is utilized to capture spring movement image sequences when high voltage circuit breaker operated. Then the image-matching method is used to obtain the deformation-time curve and speed-time curve, and the spring expansion and deformation parameters are extracted from it, which will lay a foundation for subsequent spring force analysis and matching state evaluation. After performing simulation tests at the experimental site, this image analyzing method could solve the complex problems of traditional mechanical sensor installation and monitoring online, status assessment of the circuit breaker spring.

  18. Decorin content and near infrared spectroscopy analysis of dried collagenous biomaterial samples.

    PubMed

    Aldema-Ramos, Mila L; Castell, Joan Carles; Muir, Zerlina E; Adzet, Jose Maria; Sabe, Rosa; Schreyer, Suzanne

    2012-12-14

    The efficient removal of proteoglycans, such as decorin, from the hide when processing it to leather by traditional means is generally acceptable and beneficial for leather quality, especially for softness and flexibility. A patented waterless or acetone dehydration method that can generate a product similar to leather called Dried Collagenous Biomaterial (known as BCD) was developed but has no effect on decorin removal efficiency. The Alcian Blue colorimetric technique was used to assay the sulfated glycosaminoglycan (sGAG) portion of decorin. The corresponding residual decorin content was correlated to the mechanical properties of the BCD samples and was comparable to the control leather made traditionally. The waterless dehydration and instantaneous chrome tanning process is a good eco-friendly alternative to transforming hides to leather because no additional effects were observed after examination using NIR spectroscopy and additional chemometric analysis.

  19. Prevalence of depressive symptoms among medical students taught using problem-based learning versus traditional methods.

    PubMed

    Aragão, José Aderval; Freire, Marianna Ribeiro de Menezes; Nolasco Farias, Lucas Guimarães; Diniz, Sarah Santana; Sant'anna Aragão, Felipe Matheus; Sant'anna Aragão, Iapunira Catarina; Lima, Tarcisio Brandão; Reis, Francisco Prado

    2018-06-01

    To compare depressive symptoms among medical students taught using problem-based learning (PBL) and the traditional method. Beck's Depression Inventory was applied to 215 medical students. The prevalence of depression was calculated as the number of individuals with depression divided by the total number in the sample from each course, with 95% confidence intervals. The statistical significance level used was 5% (p ≤ .05). Among the 215 students, 52.1% were male and 47.9% were female; and 51.6% were being taught using PBL methodology and 48.4% using traditional methods. The prevalence of depression was 29.73% with PBL and 22.12% with traditional methods. There was higher prevalence among females: 32.8% with PBL and 23.1% with traditional methods. The prevalence of depression with PBL among students up to 21 years of age was 29.4% and among those over 21 years, 32.1%. With traditional methods among students up to 21 years of age, it was 16.7%%, and among those over 21 years, 30.1%. The prevalence of depression with PBL was highest among students in the second semester and with traditional methods, in the eighth. Depressive symptoms were highly prevalent among students taught both with PBL and with traditional methods.

  20. Comparison of DIGE and post-stained gel electrophoresis with both traditional and SameSpots analysis for quantitative proteomics.

    PubMed

    Karp, Natasha A; Feret, Renata; Rubtsov, Denis V; Lilley, Kathryn S

    2008-03-01

    2-DE is an important tool in quantitative proteomics. Here, we compare the deep purple (DP) system with DIGE using both a traditional and the SameSpots approach to gel analysis. Missing values in the traditional approach were found to be a significant issue for both systems. SameSpots attempts to address the missing value problem. SameSpots was found to increase the proportion of low volume data for DP but not for DIGE. For all the analysis methods applied in this study, the assumptions of parametric tests were met. Analysis of the same images gave significantly lower noise with SameSpots (over traditional) for DP, but no difference for DIGE. We propose that SameSpots gave lower noise with DP due to the stabilisation of the spot area by the common spot outline, but this was not seen with DIGE due to the co-detection process which stabilises the area selected. For studies where measurement of small abundance changes is required, a cost-benefit analysis highlights that DIGE was significantly cheaper regardless of the analysis methods. For studies analysing large changes, DP with SameSpots could be an effective alternative to DIGE but this will be dependent on the biological noise of the system under investigation.

  1. Characterization of heavy-metal-contaminated sediment by using unsupervised multivariate techniques and health risk assessment.

    PubMed

    Wang, Yeuh-Bin; Liu, Chen-Wuing; Wang, Sheng-Wei

    2015-03-01

    This study characterized the sediment quality of the severely contaminated Erjen River in Taiwan by using multivariate analysis methods-including factor analysis (FA), self-organizing maps (SOMs), and positive matrix factorization (PMF)-and health risk assessment. The SOMs classified the dataset with similar heavy-metal-contaminated sediment into five groups. FA extracted three major factors-traditional electroplating and metal-surface processing factor, nontraditional heavy-metal-industry factor, and natural geological factor-which accounted for 80.8% of the variance. The SOMs and FA revealed the heavy-metal-contaminated-sediment hotspots in the middle and upper reaches of the major tributary in the dry season. The hazardous index value for health risk via ingestion was 0.302. PMF further qualified the source apportionment, indicating that traditional electroplating and metal-surface-processing industries comprised 47% of the health risk posed by heavy-metal-contaminated sediment. Contaminants discharged from traditional electroplating and metal-surface-processing industries in the middle and upper reaches of the major tributary must be eliminated first to improve the sediment quality in Erjen River. The proposed assessment framework for heavy-metal-contaminated sediment can be applied to contaminated-sediment river sites in other regions. Copyright © 2014 Elsevier Inc. All rights reserved.

  2. Manufacturing of Proteins and Antibodies: Chapter Downstream Processing Technologies : Harvest Operations.

    PubMed

    Turner, Richard; Joseph, Adrian; Titchener-Hooker, Nigel; Bender, Jean

    2017-08-04

    Cell harvesting is the separation or retention of cells and cellular debris from the supernatant containing the target molecule Selection of harvest method strongly depends on the type of cells, mode of bioreactor operation, process scale, and characteristics of the product and cell culture fluid. Most traditional harvesting methods use some form of filtration, centrifugation, or a combination of both for cell separation and/or retention. Filtration methods include normal flow depth filtration and tangential flow microfiltration. The ability to scale down predictably the selected harvest method helps to ensure successful production and is critical for conducting small-scale characterization studies for confirming parameter targets and ranges. In this chapter we describe centrifugation and depth filtration harvesting methods, share strategies for harvest optimization, present recent developments in centrifugation scale-down models, and review alternative harvesting technologies.

  3. Is traditional contraceptive use in Moldova associated with poverty and isolation?

    PubMed

    Lyons-Amos, Mark J; Durrant, Gabriele B; Padmadas, Sabu S

    2011-05-01

    This study investigates the correlates of traditional contraceptive use in Moldova, a poor country in Europe with one of the highest proportions of traditional contraceptive method users. The high reliance on traditional methods, particularly in the context of sub-replacement level fertility rate, has not been systematically evaluated in demographic research. Using cross-sectional data on a sub-sample of 6039 sexually experienced women from the 2005 Moldovan Demographic and Health Survey, this study hypothesizes that (a) economic and spatial disadvantages increase the likelihood of traditional method use, and (b) high exposure to family planning/reproductive health (FP/RH) programmes increases the propensity to modern method use. Multilevel multinomial models are used to examine the correlates of traditional method use controlling for exposure to sexual activity, socioeconomic and demographic characteristics and data structure. The results show that economic disadvantage increases the probability of traditional method use, but the overall effect is small. Although higher family planning media exposure decreases the reliance on traditional methods among younger women, it has only a marginal effect in increasing modern method use among older women. Family planning programmes designed to encourage women to switch from traditional to modern methods have some success--although the effect is considerably reduced in regions outside of the capital Chisinau. The study concludes that FP/RH efforts directed towards the poorest may have limited impact, but interventions targeted at older women could reduce the burden of unwanted pregnancies and abortions. Addressing differentials in accessing modern methods could improve uptake in rural areas.

  4. [Essential procedure and key methods for survey of traditional knowledge related to Chinese materia medica resources].

    PubMed

    Cheng, Gong; Huang, Lu-qi; Xue, Da-yuan; Zhang, Xiao-bo

    2014-12-01

    The survey of traditional knowledge related to Chinese materia medica resources is the important component and one of the innovative aspects of the fourth national survey of the Chinese materia medica resources. China has rich traditional knowledge of traditional Chinese medicine (TCM) and the comprehensive investigation of TCM traditional knowledge aims to promote conservation and sustainable use of Chinese materia medica resources. Building upon the field work of pilot investigations, this paper introduces the essential procedures and key methods for conducting the survey of traditional knowledge related to Chinese materia medica resources. The essential procedures are as follows. First is the preparation phrase. It is important to review all relevant literature and provide training to the survey teams so that they have clear understanding of the concept of traditional knowledge and master key survey methods. Second is the field investigation phrase. When conducting field investigations, survey teams should identify the traditional knowledge holders by using the 'snowball method', record the traditional knowledge after obtaining prior informed concerned from the traditional knowledge holders. Researchers should fill out the survey forms provided by the Technical Specification of the Fourth National Survey of Chinese Materia Medica Resources. Researchers should pay particular attention to the scope of traditional knowledge and the method of inheriting the knowledge, which are the key information for traditional knowledge holders and potential users to reach mutual agreed terms to achieve benefit sharing. Third is the data compilation and analysis phrase. Researchers should try to compile and edit the TCM traditional knowledge in accordance with intellectual property rights requirements so that the information collected through the national survey can serve as the basic data for the TCM traditional knowledge database. The key methods of the survey include regional division of Chinese materia medica resources, interview of key information holders and standardization of information.' In particular, using "snowball method" can effectively identify traditional knowledge holder in the targeted regions and ensuring traditional knowledge holders receiving prior informed concerned before sharing the information with researcher to make sure the rights of traditional knowledge holders are protected. Employing right survey methods is not only the key to obtain traditional knowledge related to Chinese materia medica resources, but also the pathway to fulfill the objectives of access and benefit sharing stipulated in Convention on Biological Resources. It will promote the legal protection of TCM traditional knowledge and conservation of TCM intangible, cultural heritage.

  5. In-Process Atomic-Force Microscopy (AFM) Based Inspection

    PubMed Central

    Mekid, Samir

    2017-01-01

    A new in-process atomic-force microscopy (AFM) based inspection is presented for nanolithography to compensate for any deviation such as instantaneous degradation of the lithography probe tip. Traditional method used the AFM probes for lithography work and retract to inspect the obtained feature but this practice degrades the probe tip shape and hence, affects the measurement quality. This paper suggests a second dedicated lithography probe that is positioned back-to-back to the AFM probe under two synchronized controllers to correct any deviation in the process compared to specifications. This method shows that the quality improvement of the nanomachining, in progress probe tip wear, and better understanding of nanomachining. The system is hosted in a recently developed nanomanipulator for educational and research purposes. PMID:28561747

  6. Comparison of quality attributes of buffalo meat curry at different storage temperature.

    PubMed

    Kandeepan, Gurunathan; Anjaneyulu, Anne Seet Ram; Kondaiah, Napa; Mendiratta, Sanjod Kumar

    2011-01-01

    The product quality of curry is determined by the food animal source, raw materials and the method of processing. Moreover the scientific information on processing and quality of traditional buffalo meat curry from different groups of buffaloes is not available. This study was undertaken to develop processed curry from different buffalo groups and to compare its quality during storage at ambient and refrigeration temperature. The meat samples were collected from the longissimus dorsi muscle of the carcasses from each group of buffaloes slaughtered according to the traditional halal method. Buffalo meat curry was prepared in a pressure cooker with the standardized formulation. This final product was subjected to evaluation of quality and shelf life. To evaluate the effect of different groups of meat samples on the quality of curry, product yield, pH, proximate composition, water activity (aw), thiobarbituric acid reactive substances (TBARS), calorific value, sensory attributes and microbiological assay were determined The energy of meat curry from young buffaloes was significantly lower than the meat curry from spent animal groups. The overall acceptability of curry decreased significantly during 3 days ambient storage compared to refrigeration storage. Scientific processing by adopting good manufacturing practices and suitable packaging helped greatly to improve the shelf life of the ambient temperature stored buffalo meat curry. Buffalo meat curry from young male group showed better product characteristics and overall acceptability scores than spent buffalo group.

  7. Alcohols as alkylating agents in heteroarene C–H functionalization

    PubMed Central

    Jin, Jian; MacMillan, David W. C.

    2015-01-01

    Redox processes and radical intermediates are found in many biochemical processes, including deoxyribonucleotide synthesis and oxidative DNA damage1. One of the core principles that underlies DNA biosynthesis is the radical-mediated elimnation of H2O to deoxygenate ribonucleotides, an example of ‘spin-center shift’ (SCS)2, during which an alcohol C–O bond is cleaved, resulting in a carbon-centered radical intermediate. While SCS is a well-understood biochemical process, it is underutilized by the synthetic organic chemistry community. We wondered whether it would be possible to take advantage of this naturally occurring process to accomplish mild, non-traditional alkylations using alcohols as radical precursors. Considering traditional radical-based alkylation methods require the use of stoichiometric oxidants, elevated temperatures, or peroxides3–7, the development of a mild protocol using simple and abundant alkylating agents would have significant utility in the synthesis of diversely functionalized pharmacophores. In this manuscript, we describe the successful execution of this idea via the development of a dual catalytic alkylation of heteroarenes using alcohols as mild alkylating reagents. This method represents the first broadly applicable use of unactivated alcohols as latent alkylating reagents, achieved via the successful merger of photoredox and hydrogen atom transfer (HAT) catalysis. The utility of this multi-catalytic protocol has been demonstrated through the late-stage functionalization of the medicinal agents, fasudil and milrinone. PMID:26308895

  8. Multivariate cross-frequency coupling via generalized eigendecomposition

    PubMed Central

    Cohen, Michael X

    2017-01-01

    This paper presents a new framework for analyzing cross-frequency coupling in multichannel electrophysiological recordings. The generalized eigendecomposition-based cross-frequency coupling framework (gedCFC) is inspired by source-separation algorithms combined with dynamics of mesoscopic neurophysiological processes. It is unaffected by factors that confound traditional CFC methods—such as non-stationarities, non-sinusoidality, and non-uniform phase angle distributions—attractive properties considering that brain activity is neither stationary nor perfectly sinusoidal. The gedCFC framework opens new opportunities for conceptualizing CFC as network interactions with diverse spatial/topographical distributions. Five specific methods within the gedCFC framework are detailed, these are validated in simulated data and applied in several empirical datasets. gedCFC accurately recovers physiologically plausible CFC patterns embedded in noise that causes traditional CFC methods to perform poorly. The paper also demonstrates that spike-field coherence in multichannel local field potential data can be analyzed using the gedCFC framework, which provides significant advantages over traditional spike-field coherence analyses. Null-hypothesis testing is also discussed. DOI: http://dx.doi.org/10.7554/eLife.21792.001 PMID:28117662

  9. Cross-coherent vector sensor processing for spatially distributed glider networks.

    PubMed

    Nichols, Brendan; Sabra, Karim G

    2015-09-01

    Autonomous underwater gliders fitted with vector sensors can be used as a spatially distributed sensor array to passively locate underwater sources. However, to date, the positional accuracy required for robust array processing (especially coherent processing) is not achievable using dead-reckoning while the gliders remain submerged. To obtain such accuracy, the gliders can be temporarily surfaced to allow for global positioning system contact, but the acoustically active sea surface introduces locally additional sensor noise. This letter demonstrates that cross-coherent array processing, which inherently mitigates the effects of local noise, outperforms traditional incoherent processing source localization methods for this spatially distributed vector sensor network.

  10. Effect of bioaugmented inoculation on microbiota dynamics during solid-state fermentation of Daqu starter using autochthonous of Bacillus, Pediococcus, Wickerhamomyces and Saccharomycopsis.

    PubMed

    Li, Pan; Lin, Weifeng; Liu, Xiong; Wang, Xiaowen; Gan, Xing; Luo, Lixin; Lin, Wei-Tie

    2017-02-01

    Daqu, a traditional fermentation starter that is used for Chinese liquor and vinegar production, is still manufactured through a traditional spontaneous solid-state fermentation process with no selected microorganisms are intentionally inoculated. The aim of this work was to analyze the microbiota dynamics during the solid-state fermentation process of Daqu using a traditional and bioaugmented inoculation with autochthonous of Bacillus, Pediococcus, Saccharomycopsis and Wickerhamomyces at an industrial scale. Highly similar dynamics of physicochemical parameters, enzymatic activities and microbial communities were observed during the traditional and bioaugmented solid-state fermentation processes. Both in the two cases, groups of Streptophyta, Rickettsiales and Xanthomonadales only dominated the first two days, but Bacillales and Eurotiales became predominant members after 2 and 10 days fermentation, respectively. Phylotypes of Enterobacteriales, Lactobacillales, Saccharomycetales and Mucorales dominated the whole fermentation process. No significant difference (P > 0.05) in microbial structure was observed between the traditional and bioaugmented fermentation processes. However, slightly higher microbial richness was found during the bioaugmented fermentation process after 10 days fermentation. Our results reinforced the microbiota dynamic stability during the solid-state fermentation process of Daqu, and might aid in controlling the traditional Daqu manufacturing process. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. [Progress on studies of impact on CYP450 enzymes activity of traditional Chinese medicine by Cocktail probe substrates approach].

    PubMed

    Du, Xi; He, Xin; Huang, Yu-Hong; Li, Zi-Qiang

    2016-12-01

    Cocktail probe substrates approach is a fast, sensitive and high through put method to determine cytochrome P450 enzymes activity. It has been widely used to screen early drug development, analyze drug metabolism types and confirm the metabolism pathways, study drug-drug interactions, optimize clinical regimen, evaluate post marketing drugs and help liver/kidney pathological studies. This article reviewed characteristics of Cocktail probe substrates, focused on the application to traditional Chinese medicine to CYP450 system as follows: the metabolic pathway research of Chinese herb active ingredients; processing way and compatibility of medical herbs affect CYP450; find out the metabolic characteristic of Chinese patent medicine, study in pharmacy of national minority; do research in liver protective effect of traditional Chinese medicine and evaluate traditional Chinese medicine syndromes in animal models. This article make a summary of existing research results and also make a comparison of cocktail probe substrates approach application to western medicine and Chinese medicine. Copyright© by the Chinese Pharmaceutical Association.

  12. [Research and development on efficacy of Chinese herbal compound].

    PubMed

    Liu, Jian-Xun; Ren, Jian-Xun; Lin, Cheng-Ren

    2016-03-01

    The efficacy not only is summarized by clinical effect of Chinese herbal compound on theory of traditional Chinese medicine, but also is manifested to clinical effect by interaction of many intricate chemical substances. The efficacy of Chinese herbal compound is current research focus in field of traditional Chinese medicine. By currently knowing in different aspects which included the progression in efficacy of Chinese herbal compound, symptomatic efficacy of Chinese herbal compound, the relationship between the efficacy and pharmacologic effect of Chinese herbal compound, the efficacy related pharmacodynamic substance and the evaluation of efficacy, it had been summarized mainly problems and methods in research and development process of the efficacy of Chinese herbal compound in this paper. Paper also elucidated problems that need to pay attention in research of efficacy in order to provide references for clinical and experimental studies of efficacy in Chinese herbal compound, boost research and development level of new traditional Chinese drug and facilitate modernization of traditional Chinese medicines. Copyright© by the Chinese Pharmaceutical Association.

  13. Integrating conflict analysis and consensus reaching in a decision support system for water resource management.

    PubMed

    Giordano, R; Passarella, G; Uricchio, V F; Vurro, M

    2007-07-01

    The importance of shared decision processes in water management derives from the awareness of the inadequacy of traditional--i.e. engineering--approaches in dealing with complex and ill-structured problems. It is becoming increasingly obvious that traditional problem solving and decision support techniques, based on optimisation and factual knowledge, have to be combined with stakeholder based policy design and implementation. The aim of our research is the definition of an integrated decision support system for consensus achievement (IDSS-C) able to support a participative decision-making process in all its phases: problem definition and structuring, identification of the possible alternatives, formulation of participants' judgments, and consensus achievement. Furthermore, the IDSS-C aims at structuring, i.e. systematising the knowledge which has emerged during the participative process in order to make it comprehensible for the decision-makers and functional for the decision process. Problem structuring methods (PSM) and multi-group evaluation methods (MEM) have been integrated in the IDSS-C. PSM are used to support the stakeholders in providing their perspective of the problem and to elicit their interests and preferences, while MEM are used to define not only the degree of consensus for each alternative, highlighting those where the agreement is high, but also the consensus label for each alternative and the behaviour of individuals during the participative decision-making. The IDSS-C is applied experimentally to a decision process regarding the use of treated wastewater for agricultural irrigation in the Apulia Region (southern Italy).

  14. A new chapter in pharmaceutical manufacturing: 3D-printed drug products.

    PubMed

    Norman, James; Madurawe, Rapti D; Moore, Christine M V; Khan, Mansoor A; Khairuzzaman, Akm

    2017-01-01

    FDA recently approved a 3D-printed drug product in August 2015, which is indicative of a new chapter for pharmaceutical manufacturing. This review article summarizes progress with 3D printed drug products and discusses process development for solid oral dosage forms. 3D printing is a layer-by-layer process capable of producing 3D drug products from digital designs. Traditional pharmaceutical processes, such as tablet compression, have been used for decades with established regulatory pathways. These processes are well understood, but antiquated in terms of process capability and manufacturing flexibility. 3D printing, as a platform technology, has competitive advantages for complex products, personalized products, and products made on-demand. These advantages create opportunities for improving the safety, efficacy, and accessibility of medicines. Although 3D printing differs from traditional manufacturing processes for solid oral dosage forms, risk-based process development is feasible. This review highlights how product and process understanding can facilitate the development of a control strategy for different 3D printing methods. Overall, the authors believe that the recent approval of a 3D printed drug product will stimulate continual innovation in pharmaceutical manufacturing technology. FDA encourages the development of advanced manufacturing technologies, including 3D-printing, using science- and risk-based approaches. Published by Elsevier B.V.

  15. Development of volatile compounds during the manufacture of dry-cured "lacón," a Spanish traditional meat product.

    PubMed

    Purriños, Laura; Bermúdez, Roberto; Franco, Daniel; Carballo, Javier; Lorenzo, José M

    2011-01-01

    Volatile compounds were determined throughout the manufacture of dry-cured "lacón," a traditional dry-salted, and ripened meat product made in the north-west of Spain from the foreleg of the pig following a similar process to that of dry-cured ham. Volatiles were extracted by a purge-and-trap method and analyzed by gas chromatographic/mass spectrometry. One hundred and two volatile compounds were identified. In raw material, only 34 volatile compounds were found and at very low levels. The number of volatile compounds increased during processing. The substances identified belonged to several chemical classes: aldehydes (23), alcohols (9), ketones (15), hydrocarbons (37), esters (4), acids (3), furans (4), sulphur compounds (1), chloride compounds (1), and other compounds (4). Results indicated that the most abundant chemical family in flavor at the end of the manufacturing process was aldehydes, followed by hydrocarbons and ketones. Lipids were the most important precursor of flavor compounds of dry-cured "lacón."

  16. Stochastic production phase design for an open pit mining complex with multiple processing streams

    NASA Astrophysics Data System (ADS)

    Asad, Mohammad Waqar Ali; Dimitrakopoulos, Roussos; van Eldert, Jeroen

    2014-08-01

    In a mining complex, the mine is a source of supply of valuable material (ore) to a number of processes that convert the raw ore to a saleable product or a metal concentrate for production of the refined metal. In this context, expected variation in metal content throughout the extent of the orebody defines the inherent uncertainty in the supply of ore, which impacts the subsequent ore and metal production targets. Traditional optimization methods for designing production phases and ultimate pit limit of an open pit mine not only ignore the uncertainty in metal content, but, in addition, commonly assume that the mine delivers ore to a single processing facility. A stochastic network flow approach is proposed that jointly integrates uncertainty in supply of ore and multiple ore destinations into the development of production phase design and ultimate pit limit. An application at a copper mine demonstrates the intricacies of the new approach. The case study shows a 14% higher discounted cash flow when compared to the traditional approach.

  17. Adopting best practices: "Agility" moves from software development to healthcare project management.

    PubMed

    Kitzmiller, Rebecca; Hunt, Eleanor; Sproat, Sara Breckenridge

    2006-01-01

    It is time for a change in mindset in how nurses operationalize system implementations and manage projects. Computers and systems have evolved over time from unwieldy mysterious machines of the past to ubiquitous computer use in every aspect of daily lives and work sites. Yet, disconcertingly, the process used to implement these systems has not evolved. Technology implementation does not need to be a struggle. It is time to adapt traditional plan-driven implementation methods to incorporate agile techniques. Agility is a concept borrowed from software development and is presented here because it encourages flexibility, adaptation, and continuous learning as part of the implementation process. Agility values communication and harnesses change to an advantage, which facilitates the natural evolution of an adaptable implementation process. Specific examples of agility in an implementation are described, and plan-driven implementation stages are adapted to incorporate relevant agile techniques. This comparison demonstrates how an agile approach enhances traditional implementation techniques to meet the demands of today's complex healthcare environments.

  18. a New Approach for Accuracy Improvement of Pulsed LIDAR Remote Sensing Data

    NASA Astrophysics Data System (ADS)

    Zhou, G.; Huang, W.; Zhou, X.; He, C.; Li, X.; Huang, Y.; Zhang, L.

    2018-05-01

    In remote sensing applications, the accuracy of time interval measurement is one of the most important parameters that affect the quality of pulsed lidar data. The traditional time interval measurement technique has the disadvantages of low measurement accuracy, complicated circuit structure and large error. A high-precision time interval data cannot be obtained in these traditional methods. In order to obtain higher quality of remote sensing cloud images based on the time interval measurement, a higher accuracy time interval measurement method is proposed. The method is based on charging the capacitance and sampling the change of capacitor voltage at the same time. Firstly, the approximate model of the capacitance voltage curve in the time of flight of pulse is fitted based on the sampled data. Then, the whole charging time is obtained with the fitting function. In this method, only a high-speed A/D sampler and capacitor are required in a single receiving channel, and the collected data is processed directly in the main control unit. The experimental results show that the proposed method can get error less than 3 ps. Compared with other methods, the proposed method improves the time interval accuracy by at least 20 %.

  19. First arrival time picking for microseismic data based on DWSW algorithm

    NASA Astrophysics Data System (ADS)

    Li, Yue; Wang, Yue; Lin, Hongbo; Zhong, Tie

    2018-03-01

    The first arrival time picking is a crucial step in microseismic data processing. When the signal-to-noise ratio (SNR) is low, however, it is difficult to get the first arrival time accurately with traditional methods. In this paper, we propose the double-sliding-window SW (DWSW) method based on the Shapiro-Wilk (SW) test. The DWSW method is used to detect the first arrival time by making full use of the differences between background noise and effective signals in the statistical properties. Specifically speaking, we obtain the moment corresponding to the maximum as the first arrival time of microseismic data when the statistic of our method reaches its maximum. Hence, in our method, there is no need to select the threshold, which makes the algorithm more facile when the SNR of microseismic data is low. To verify the reliability of the proposed method, a series of experiments is performed on both synthetic and field microseismic data. Our method is compared with the traditional short-time and long-time average (STA/LTA) method, the Akaike information criterion, and the kurtosis method. Analysis results indicate that the accuracy rate of the proposed method is superior to that of the other three methods when the SNR is as low as - 10 dB.

  20. Evaluation of a modified team based learning method for teaching general embryology to 1st year medical graduate students.

    PubMed

    Shankar, Nachiket; Roopa, R

    2009-01-01

    To encourage student participation in the learning process, the authors introduced a modified team based learning (TBL) method to cover two general embryology topics in the 1st year MBBS curriculum. The aim of this study was to evaluate students' perception of this method vis-à-vis the lecture method of teaching. A questionnaire was used to survey and evaluate the perceptions of 1st year MBBS students at the Department of Anatomy at our medical college in India. A total of eight classes were allotted to cover General Embryology. Six of these classes were conducted using the traditional didactic lecture method. Two topics were covered using the modified TBL method. Five teams of students were constituted, and each team was given handouts which contained basic factual material, four clinical case histories, and previous university exam questions from the topic. On the day of the session, these were discussed in the presence of the faculty facilitator. Students evaluated these sessions through a questionnaire. A majority of students felt that the modified TBL sessions were better at fulfilling learning objectives (46 students, 85%), enabled better understanding (43 students, 79%), were more interesting (43 students, 81%), ensured greater student participation (51 students, 94%) and involved greater effort on the part of students (53 students, 98%), as compared to traditional teaching methods. Most of the students (43 students, 79%) opined that more such sessions should be organized in the future. Responses from students show that the modified TBL classes could be utilized judiciously along with the traditional didactic lectures for teaching embryology.

  1. Digital Microdroplet Ejection Technology-Based Heterogeneous Objects Prototyping

    PubMed Central

    Yang, Jiquan; Feng, Chunmei; Yang, Jianfei; Zhu, Liya; Guo, Aiqing

    2016-01-01

    An integrate fabrication framework is presented to build heterogeneous objects (HEO) using digital microdroplets injecting technology and rapid prototyping. The heterogeneous materials part design and manufacturing method in structure and material was used to change the traditional process. The net node method was used for digital modeling that can configure multimaterials in time. The relationship of material, color, and jetting nozzle was built. The main important contributions are to combine the structure, material, and visualization in one process and give the digital model for manufacture. From the given model, it is concluded that the method is effective for HEO. Using microdroplet rapid prototyping and the model given in the paper HEO could be gotten basically. The model could be used in 3D biomanufacturing. PMID:26981110

  2. Digital Microdroplet Ejection Technology-Based Heterogeneous Objects Prototyping.

    PubMed

    Li, Na; Yang, Jiquan; Feng, Chunmei; Yang, Jianfei; Zhu, Liya; Guo, Aiqing

    2016-01-01

    An integrate fabrication framework is presented to build heterogeneous objects (HEO) using digital microdroplets injecting technology and rapid prototyping. The heterogeneous materials part design and manufacturing method in structure and material was used to change the traditional process. The net node method was used for digital modeling that can configure multimaterials in time. The relationship of material, color, and jetting nozzle was built. The main important contributions are to combine the structure, material, and visualization in one process and give the digital model for manufacture. From the given model, it is concluded that the method is effective for HEO. Using microdroplet rapid prototyping and the model given in the paper HEO could be gotten basically. The model could be used in 3D biomanufacturing.

  3. Fast principal component analysis for stacking seismic data

    NASA Astrophysics Data System (ADS)

    Wu, Juan; Bai, Min

    2018-04-01

    Stacking seismic data plays an indispensable role in many steps of the seismic data processing and imaging workflow. Optimal stacking of seismic data can help mitigate seismic noise and enhance the principal components to a great extent. Traditional average-based seismic stacking methods cannot obtain optimal performance when the ambient noise is extremely strong. We propose a principal component analysis (PCA) algorithm for stacking seismic data without being sensitive to noise level. Considering the computational bottleneck of the classic PCA algorithm in processing massive seismic data, we propose an efficient PCA algorithm to make the proposed method readily applicable for industrial applications. Two numerically designed examples and one real seismic data are used to demonstrate the performance of the presented method.

  4. Most Probable Number Rapid Viability PCR Method to Detect Viable Spores of Bacillus anthracis in Swab Samples

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Letant, S E; Kane, S R; Murphy, G A

    2008-05-30

    This note presents a comparison of Most-Probable-Number Rapid Viability (MPN-RV) PCR and traditional culture methods for the quantification of Bacillus anthracis Sterne spores in macrofoam swabs generated by the Centers for Disease Control and Prevention (CDC) for a multi-center validation study aimed at testing environmental swab processing methods for recovery, detection, and quantification of viable B. anthracis spores from surfaces. Results show that spore numbers provided by the MPN RV-PCR method were in statistical agreement with the CDC conventional culture method for all three levels of spores tested (10{sup 4}, 10{sup 2}, and 10 spores) even in the presence ofmore » dirt. In addition to detecting low levels of spores in environmental conditions, the MPN RV-PCR method is specific, and compatible with automated high-throughput sample processing and analysis protocols.« less

  5. Dehydration of Traditional Dried Instant Noodle (Mee Siput) Using Controlled Temperature & Humidity Dryer

    NASA Astrophysics Data System (ADS)

    Mamat, K. A.; Yusof, M. S.; Yusoff, Wan Fauziah Wan; Zulafif Rahim, M.; Hassan, S.; Rahman, M. Qusyairi. A.; Karim, M. A. Abd

    2017-05-01

    Drying process is an essential step to produce instant noodles. Yet, the industries especially Small and Medium Enterprises (SMEs), is seeking for an efficient method to dry the noodles. This paper discusses the performance of an invented drying system which employed heating and humidifying process. The drying system was tested using 30 kilogram of the raw noodle known as “Mee Siput”. Temperature controlled system were used in the study to control the temperature of the drying process and prevent the dried noodles from damage by maintaining the temperature of lower than 80°C. The analysis shows that the system was drastically decreased the humidity from 80% to 40% just after 200 minutes of the drying process. The complete dehydration time of noodle has also decreased to only 4 hours from 16 hours when using traditional drying system without sacrificed the good quality of the dried noodle. In overall, the invented system believed to increase the production capacity of the noodle, reduce cost of production which would highly beneficial for Small Medium Industries (SMEs) in Malaysia.

  6. Riverine Settlement Adaptation Characteristic in Mentaya River, East Kotawaringin Regency, Kalimantan Province

    NASA Astrophysics Data System (ADS)

    Esariti, L.; Yuliastuti, N.; Ratih, N. K.

    2018-02-01

    The research looks for the importance of riverine settlement preservation as one of the efforts to carry out sustainable management of a traditional settlement. East Kalimantan, more specifically riverine settlement in Mentaya River is known as one of the traditional settlements that put river as the central of their livelihood activities. The theory of Rapopport [1] was used to investigate the importance of cultural aspect influence to the settlement process, and to seek for the behavioural and environment relationship in determining the pattern of adaptation process. Mix method approach was conducted by utilizing in depth interviews among 40 respondents within three districts, namely in Baamang, Mentaya Seberang and Mentawa Baru Ketapang subdistrict. The result shows that culture dominantly affect the process of settlement adaptation, especially the aspect of family structure, social network, and kinship. The adaptation pattern is influenced significantly by physical environment, type of physical condition of the houses, economic condition and the degree of heritage preservation motive. It sums up that adaptation process could be effective if the integration of culture, activities and government regulations is performed.

  7. [Consideration about chemistry, manufacture and control (CMC) key problems in simplified registration of classical traditional Chinese medicine excellent prescriptions].

    PubMed

    Wang, Zhi-Min; Liu, Ju-Yan; Liu, Xiao-Qian; Wang, De-Qin; Yan, Li-Hua; Zhu, Jin-Jin; Gao, Hui-Min; Li, Chun; Wang, Jin-Yu; Li, Chu-Yuan; Ni, Qing-Chun; Huang, Ji-Sheng; Lin, Juan

    2017-05-01

    As an outstanding representative of traditional Chinese medicine(TCM) prescriptions accumulated from famous TCM doctors' clinical experiences in past dynasties, classical TCM excellent prescriptions (cTCMeP) are the most valuable part of TCM system. To support the research and development of cTCMeP, a series of regulations and measures were issued to encourage its simplified registration. There is still a long-way to go because many key problems and puzzles about technology, registration and administration in cTCMeP R&D process are not resolved. Based on the analysis of registration and management regulations of botanical drug products in FDA of USA and Japan, and EMA of Europe, the possible key problems and countermeasures in chemistry, manufacture and control (CMC) of simplified registration of cTCMeP were analyzed on the consideration of its actual situation. The method of "reference decoction extract by traditional prescription" (RDETP) was firstly proposed as standard to evaluate the quality and preparation uniformity between the new developing product under simplified registration and traditional original usages of cTCMeP, instead of Standard Decoction method in Japan. "Totality of the evidence" approach, mass balance and bioassay/biological assay of cTCMeP were emphatically suggested to introduce to the quality uniformity evaluation system in the raw drug material, drug substance and final product between the modern product and traditional decoction. Copyright© by the Chinese Pharmaceutical Association.

  8. [Physical fingerprint for quality control of traditional Chinese medicine extract powders].

    PubMed

    Zhang, Yi; Xu, Bing; Sun, Fei; Wang, Xin; Zhang, Na; Shi, Xin-Yuan; Qiao, Yan-Jiang

    2016-06-01

    The physical properties of both raw materials and excipients are closely correlated with the quality of traditional Chinese medicine preparations in oral solid dosage forms. In this paper, based on the concept of the chemical fingerprint for quality control of traditional Chinese medicine products, the method of physical fingerprint for quality evaluation of traditional Chinese medicine extract powders was proposed. This novel physical fingerprint was built by the radar map, and consisted of five primary indexes (i.e. stackablity, homogeneity, flowability, compressibility and stability) and 12 secondary indexes (i.e. bulk density, tap density, particle size<50 μm percentage, relative homogeneity index, hausner ratio, angle of repose, powder flow time, inter-particle porosity, Carr index, cohesion index, loss on drying, hygroscopicity). Panax notoginseng saponins (PNS) extract was taken for an example. This paper introduced the application of physical fingerprint in the evaluation of source-to-source and batch-to-batch quality consistence of PNS extract powders. Moreover, the physical fingerprint of PNS was built by calculating the index of parameters, the index of parametric profile and the index of good compressibility, in order to successfully predict the compressibility of the PNS extract powder and relevant formulations containing PNS extract powder and conventional pharmaceutical excipients. The results demonstrated that the proposed method could not only provide new insights into the development and process control of traditional Chinese medicine solid dosage forms. Copyright© by the Chinese Pharmaceutical Association.

  9. Close partner as sculptor of the ideal self: behavioral affirmation and the Michelangelo phenomenon.

    PubMed

    Drigotas, S M; Rusbult, C E; Wieselquist, J; Whitton, S W

    1999-08-01

    This work incorporates concepts from the behavioral confirmation tradition, self tradition, and interdependence tradition to identify an interpersonal process termed the Michelangelo phenomenon. The Michelangelo phenomenon describes the means by which the self is shaped by a close partner's perceptions and behavior. Specifically, self movement toward the ideal self is described as a product of partner affirmation, or the degree to which a partner's perceptions of the self and behavior toward the self are congruent with the self's ideal. The results of 4 studies revealed strong associations between perceived partner affirmation and self movement toward the ideal self, using a variety of participant populations and measurement methods. In addition, perceived partner affirmation--particularly perceived partner behavioral affirmation--was strongly associated with quality of couple functioning and stability in ongoing relationships.

  10. A Deconvolution Approach for the Mapping of Acoustic Sources (DAMAS) Determined from Phased Microphone Arrays

    NASA Technical Reports Server (NTRS)

    Brooks, Thomas F.; Humphreys, William M.

    2006-01-01

    Current processing of acoustic array data is burdened with considerable uncertainty. This study reports an original methodology that serves to demystify array results, reduce misinterpretation, and accurately quantify position and strength of acoustic sources. Traditional array results represent noise sources that are convolved with array beamform response functions, which depend on array geometry, size (with respect to source position and distributions), and frequency. The Deconvolution Approach for the Mapping of Acoustic Sources (DAMAS) method removes beamforming characteristics from output presentations. A unique linear system of equations accounts for reciprocal influence at different locations over the array survey region. It makes no assumption beyond the traditional processing assumption of statistically independent noise sources. The full rank equations are solved with a new robust iterative method. DAMAS is quantitatively validated using archival data from a variety of prior high-lift airframe component noise studies, including flap edge/cove, trailing edge, leading edge, slat, and calibration sources. Presentations are explicit and straightforward, as the noise radiated from a region of interest is determined by simply summing the mean-squared values over that region. DAMAS can fully replace existing array processing and presentations methodology in most applications. It appears to dramatically increase the value of arrays to the field of experimental acoustics.

  11. An approach to optimize the batch mixing process for improving the quality consistency of the products made from traditional Chinese medicines*

    PubMed Central

    Yan, Bin-jun; Qu, Hai-bin

    2013-01-01

    The efficacy of traditional Chinese medicine (TCM) is based on the combined effects of its constituents. Variation in chemical composition between batches of TCM has always been the deterring factor in achieving consistency in efficacy. The batch mixing process can significantly reduce the batch-to-batch quality variation in TCM extracts by mixing them in a well-designed proportion. However, reducing the quality variation without sacrificing too much of the production efficiency is one of the challenges. Accordingly, an innovative and practical batch mixing method aimed at providing acceptable efficiency for industrial production of TCM products is proposed in this work, which uses a minimum number of batches of extracts to meet the content limits. The important factors affecting the utilization ratio of the extracts (URE) were studied by simulations. The results have shown that URE was affected by the correlation between the contents of constituents, and URE decreased with the increase in the number of targets and the relative standard deviations of the contents. URE could be increased by increasing the number of storage tanks. The results have provided a reference for designing the batch mixing process. The proposed method has possible application value in reducing the quality variation in TCM and providing acceptable production efficiency simultaneously. PMID:24190450

  12. An approach to optimize the batch mixing process for improving the quality consistency of the products made from traditional Chinese medicines.

    PubMed

    Yan, Bin-jun; Qu, Hai-bin

    2013-11-01

    The efficacy of traditional Chinese medicine (TCM) is based on the combined effects of its constituents. Variation in chemical composition between batches of TCM has always been the deterring factor in achieving consistency in efficacy. The batch mixing process can significantly reduce the batch-to-batch quality variation in TCM extracts by mixing them in a well-designed proportion. However, reducing the quality variation without sacrificing too much of the production efficiency is one of the challenges. Accordingly, an innovative and practical batch mixing method aimed at providing acceptable efficiency for industrial production of TCM products is proposed in this work, which uses a minimum number of batches of extracts to meet the content limits. The important factors affecting the utilization ratio of the extracts (URE) were studied by simulations. The results have shown that URE was affected by the correlation between the contents of constituents, and URE decreased with the increase in the number of targets and the relative standard deviations of the contents. URE could be increased by increasing the number of storage tanks. The results have provided a reference for designing the batch mixing process. The proposed method has possible application value in reducing the quality variation in TCM and providing acceptable production efficiency simultaneously.

  13. Trends in the nursing doctoral comprehensive examination process: a national survey.

    PubMed

    Mawn, Barbara E; Goldberg, Shari

    2012-01-01

    The doctoral comprehensive or qualifying examination (CE/QE) is a traditional rite of passage into the community of scholars for the nursing profession. This exploratory, descriptive cross-sectional study examined trends in the process, timing, and methodology of comprehensive and qualifying examinations in nursing doctoral programs in the United States. Administrators from 45 schools responded to an online survey from 27 states across the country (37% response rate). Participants reported wide variations in the process. The most common method of implementation was the written take-home test (47%), two thirds of which had a subsequent oral examination. Eleven survey respondents (24%) reported using a form of the traditional written, timed, on-site examination; however, only 4 of these also followed up with an oral defense. Nine schools (20%) moved to a requirement for a written publishable paper; three schools consider the written proposal and its defense as the CE/QE. Approximately half had changed their policy in the past 5 years. With the increase in nursing doctor of philosophy programs over the past decade, information is needed to facilitate the development of methods to achieve program outcomes. An understanding of national CE/QE trends can provide a starting point for discussion and allow innovative ideas to meet the need of individual programs. Copyright © 2012 Elsevier Inc. All rights reserved.

  14. Fundamental and applied studies in nanoparticle biomedical imaging, stabilization, and processing

    NASA Astrophysics Data System (ADS)

    Pansare, Vikram J.

    Nanoparticle carrier systems are gaining importance in the rapidly expanding field of biomedical whole animal imaging where they provide long circulating, real time imaging capability. This thesis presents a new paradigm in imaging whereby long wavelength fluorescent or photoacoustically active contrast agents are embedded in the hydrophobic core of nanocarriers formed by Flash NanoPrecipitation. The long wavelength allows for improved optical penetration depth. Compared to traditional contrast agents where fluorophores are placed on the surface, this allows for improved signal, increased stability, and molecular targeting capabilities. Several types of long wavelength hydrophobic dyes based on acene, cyanine, and bacteriochlorin scaffolds are utilized and animal results obtained for nanocarrier systems used in both fluorescent and photoacoustic imaging modes. Photoacoustic imaging is particularly promising due to its high resolution, excellent penetration depth, and ability to provide real-time functional information. Fundamental studies in nanoparticle stabilization are also presented for two systems: model alumina nanoparticles and charge stabilized polystyrene nanoparticles. Motivated by the need for stable suspensions of alumina-based nanocrystals for security printing applications, results are presented for the adsorption of various small molecule charged hydrophobes onto the surface of alumina nanoparticles. Results are also presented for the production of charge stabilized polystyrene nanoparticles via Flash NanoPrecipitation, allowing for the independent control of polymer molecular weight and nanoparticle size, which is not possible by traditional emulsion polymerization routes. Lastly, methods for processing nanoparticle systems are explored. The increasing use of nanoparticle therapeutics in the pharmaceutical industry has necessitated the development of scalable, industrially relevant processing methods. Ultrafiltration is particularly well suited for concentrating and purifying macromolecular suspensions. Processing parameters are defined and optimized for PEGylated nanoparticles, charge stabilized latices, and solutions of albumin. The fouling characteristics are compared and scale-up recommendations made. Finally, a pilot scale spray drying system to produce stable nanocrystalline powders of highly crystalline drugs which cannot be stably formulated by traditional spray drying methods is presented. To accomplish this, a novel mixing device was developed and implemented at pilot scale, demonstrating feasibility beyond the lab scale.

  15. High-efficiency non-uniformity correction for wide dynamic linear infrared radiometry system

    NASA Astrophysics Data System (ADS)

    Li, Zhou; Yu, Yi; Tian, Qi-Jie; Chang, Song-Tao; He, Feng-Yun; Yin, Yan-He; Qiao, Yan-Feng

    2017-09-01

    Several different integration times are always set for a wide dynamic linear and continuous variable integration time infrared radiometry system, therefore, traditional calibration-based non-uniformity correction (NUC) are usually conducted one by one, and furthermore, several calibration sources required, consequently makes calibration and process of NUC time-consuming. In this paper, the difference of NUC coefficients between different integration times have been discussed, and then a novel NUC method called high-efficiency NUC, which combines the traditional calibration-based non-uniformity correction, has been proposed. It obtains the correction coefficients of all integration times in whole linear dynamic rangesonly by recording three different images of a standard blackbody. Firstly, mathematical procedure of the proposed non-uniformity correction method is validated and then its performance is demonstrated by a 400 mm diameter ground-based infrared radiometry system. Experimental results show that the mean value of Normalized Root Mean Square (NRMS) is reduced from 3.78% to 0.24% by the proposed method. In addition, the results at 4 ms and 70 °C prove that this method has a higher accuracy compared with traditional calibration-based NUC. In the meantime, at other integration time and temperature there is still a good correction effect. Moreover, it greatly reduces the number of correction time and temperature sampling point, and is characterized by good real-time performance and suitable for field measurement.

  16. Thermal, High Pressure, and Electric Field Processing Effects on Plant Cell Membrane Integrity and Relevance to Fruit and Vegetable Quality

    PubMed Central

    Gonzalez, Maria E; Barrett, Diane M

    2010-01-01

    Advanced food processing methods that accomplish inactivation of microorganisms but minimize adverse thermal exposure are of great interest to the food industry. High pressure (HP) and pulsed electric field (PEF) processing are commercially applied to produce high quality fruit and vegetable products in the United States, Europe, and Japan. Both microbial and plant cell membranes are significantly altered following exposure to heat, HP, or PEF. Our research group sought to quantify the degree of damage to plant cell membranes that occurs as a result of exposure to heat, HP, or PEF, using the same analytical methods. In order to evaluate whether new advanced processing methods are superior to traditional thermal processing methods, it is necessary to compare them. In this review, we describe the existing state of knowledge related to effects of heat, HP, and PEF on both microbial and plant cells. The importance and relevance of compartmentalization in plant cells as it relates to fruit and vegetable quality is described and various methods for quantification of plant cell membrane integrity are discussed. These include electrolyte leakage, cell viability, and proton nuclear magnetic resonance (1H-NMR). PMID:20492210

  17. Thermal, high pressure, and electric field processing effects on plant cell membrane integrity and relevance to fruit and vegetable quality.

    PubMed

    Gonzalez, Maria E; Barrett, Diane M

    2010-09-01

    Advanced food processing methods that accomplish inactivation of microorganisms but minimize adverse thermal exposure are of great interest to the food industry. High pressure (HP) and pulsed electric field (PEF) processing are commercially applied to produce high quality fruit and vegetable products in the United States, Europe, and Japan. Both microbial and plant cell membranes are significantly altered following exposure to heat, HP, or PEF. Our research group sought to quantify the degree of damage to plant cell membranes that occurs as a result of exposure to heat, HP, or PEF, using the same analytical methods. In order to evaluate whether new advanced processing methods are superior to traditional thermal processing methods, it is necessary to compare them. In this review, we describe the existing state of knowledge related to effects of heat, HP, and PEF on both microbial and plant cells. The importance and relevance of compartmentalization in plant cells as it relates to fruit and vegetable quality is described and various methods for quantification of plant cell membrane integrity are discussed. These include electrolyte leakage, cell viability, and proton nuclear magnetic resonance (¹H-NMR).

  18. Research on application of intelligent computation based LUCC model in urbanization process

    NASA Astrophysics Data System (ADS)

    Chen, Zemin

    2007-06-01

    Global change study is an interdisciplinary and comprehensive research activity with international cooperation, arising in 1980s, with the largest scopes. The interaction between land use and cover change, as a research field with the crossing of natural science and social science, has become one of core subjects of global change study as well as the front edge and hot point of it. It is necessary to develop research on land use and cover change in urbanization process and build an analog model of urbanization to carry out description, simulation and analysis on dynamic behaviors in urban development change as well as to understand basic characteristics and rules of urbanization process. This has positive practical and theoretical significance for formulating urban and regional sustainable development strategy. The effect of urbanization on land use and cover change is mainly embodied in the change of quantity structure and space structure of urban space, and LUCC model in urbanization process has been an important research subject of urban geography and urban planning. In this paper, based upon previous research achievements, the writer systematically analyzes the research on land use/cover change in urbanization process with the theories of complexity science research and intelligent computation; builds a model for simulating and forecasting dynamic evolution of urban land use and cover change, on the basis of cellular automation model of complexity science research method and multi-agent theory; expands Markov model, traditional CA model and Agent model, introduces complexity science research theory and intelligent computation theory into LUCC research model to build intelligent computation-based LUCC model for analog research on land use and cover change in urbanization research, and performs case research. The concrete contents are as follows: 1. Complexity of LUCC research in urbanization process. Analyze urbanization process in combination with the contents of complexity science research and the conception of complexity feature to reveal the complexity features of LUCC research in urbanization process. Urban space system is a complex economic and cultural phenomenon as well as a social process, is the comprehensive characterization of urban society, economy and culture, and is a complex space system formed by society, economy and nature. It has dissipative structure characteristics, such as opening, dynamics, self-organization, non-balance etc. Traditional model cannot simulate these social, economic and natural driving forces of LUCC including main feedback relation from LUCC to driving force. 2. Establishment of Markov extended model of LUCC analog research in urbanization process. Firstly, use traditional LUCC research model to compute change speed of regional land use through calculating dynamic degree, exploitation degree and consumption degree of land use; use the theory of fuzzy set to rewrite the traditional Markov model, establish structure transfer matrix of land use, forecast and analyze dynamic change and development trend of land use, and present noticeable problems and corresponding measures in urbanization process according to research results. 3. Application of intelligent computation research and complexity science research method in LUCC analog model in urbanization process. On the basis of detailed elaboration of the theory and the model of LUCC research in urbanization process, analyze the problems of existing model used in LUCC research (namely, difficult to resolve many complexity phenomena in complex urban space system), discuss possible structure realization forms of LUCC analog research in combination with the theories of intelligent computation and complexity science research. Perform application analysis on BP artificial neural network and genetic algorithms of intelligent computation and CA model and MAS technology of complexity science research, discuss their theoretical origins and their own characteristics in detail, elaborate the feasibility of them in LUCC analog research, and bring forward improvement methods and measures on existing problems of this kind of model. 4. Establishment of LUCC analog model in urbanization process based on theories of intelligent computation and complexity science. Based on the research on abovementioned BP artificial neural network, genetic algorithms, CA model and multi-agent technology, put forward improvement methods and application assumption towards their expansion on geography, build LUCC analog model in urbanization process based on CA model and Agent model, realize the combination of learning mechanism of BP artificial neural network and fuzzy logic reasoning, express the regulation with explicit formula, and amend the initial regulation through self study; optimize network structure of LUCC analog model and methods and procedures of model parameters with genetic algorithms. In this paper, I introduce research theory and methods of complexity science into LUCC analog research and presents LUCC analog model based upon CA model and MAS theory. Meanwhile, I carry out corresponding expansion on traditional Markov model and introduce the theory of fuzzy set into data screening and parameter amendment of improved model to improve the accuracy and feasibility of Markov model in the research on land use/cover change.

  19. 3D superwide-angle one-way propagator and its application in seismic modeling and imaging

    NASA Astrophysics Data System (ADS)

    Jia, Xiaofeng; Jiang, Yunong; Wu, Ru-Shan

    2018-07-01

    Traditional one-way wave-equation based propagators have been widely used in past decades. Comparing to two-way propagators, one-way methods have higher efficiency and lower memory demands. These two features are especially important in solving large-scale 3D problems. However, regular one-way propagators cannot simulate waves that propagate in large angles within 90° because of their inherent wide angle limitation. Traditional one-way can only propagate along the determined direction (e.g., z-direction), so simulation of turning waves is beyond the ability of one-way methods. We develop 3D superwide-angle one-way propagator to overcome angle limitation and to simulate turning waves with superwide-angle propagation angle (>90°) for modeling and imaging complex geological structures. Wavefields propagating along vertical and horizontal directions are combined using typical stacking scheme. A weight function related to the propagation angle is used for combining and updating wavefields in each propagating step. In the implementation, we use graphics processing units (GPU) to accelerate the process. Typical workflow is designed to exploit the advantages of GPU architecture. Numerical examples show that the method achieves higher accuracy in modeling and imaging steep structures than regular one-way propagators. Actually, superwide-angle one-way propagator can be applied based on any one-way method to improve the effects of seismic modeling and imaging.

  20. Electron-Ion Dynamics with Time-Dependent Density Functional Theory: Towards Predictive Solar Cell Modeling: Final Technical Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Maitra, Neepa

    2016-07-14

    This project investigates the accuracy of currently-used functionals in time-dependent density functional theory, which is today routinely used to predict and design materials and computationally model processes in solar energy conversion. The rigorously-based electron-ion dynamics method developed here sheds light on traditional methods and overcomes challenges those methods have. The fundamental research undertaken here is important for building reliable and practical methods for materials discovery. The ultimate goal is to use these tools for the computational design of new materials for solar cell devices of high efficiency.

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