78 FR 79477 - Announcement of Funding Awards, Choice Neighborhoods Grant Program, Fiscal Year 2013

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-30

... to community development centered on housing transformation. The program aims to transform...-functioning services, effective schools and education programs, public assets, public transportation, and... comprehensive neighborhood revitalization strategy, or Transformation Plan. The Transformation Plan will become...

Protected transitional solution to transformational satellite communications

NASA Astrophysics Data System (ADS)

Brand, Jerry C.

2005-06-01

As the Warfighter progresses into the next generation battlefield, transformational communications become evident as an enabling technology. Satellite communications become even more vital as the battles range over greater non-contiguous spaces. While current satellite communications provide suitable beyond line-of-sight communications and the Transformational Communications Architecture (TCA) sets the stage for sound information exchange, a realizable transition must occur to ensure successful succession to this higher level. This paper addresses the need for a planned escalation to the next generation satellite communications architecture and offers near-term alternatives. Commercial satellite systems continue to enable the Warfighter to reach back to needed information resources, providing a large majority of available bandwidth. Four areas of concentration for transition include encrypted Telemetry, Tracking and Control (or Command) (TT&C), encrypted and covered data, satellite attack detection and protection, and operational mobility. Solution methodologies include directly embedding COMSEC devices in the satellites and terminals, and supplementing existing terminals with suitable equipment and software. Future satellites planned for near-term launches can be adapted to include commercial grade and higher-level secure equipment. Alternately, the expected use of programmable modems (Software Defined Radios (SDR)) enables incorporation of powerful cipher methods approaching military standards as well as waveforms suitable for on-the-move operation. Minimal equipment and software additions on the satellites can provide reasonable attack detection and protection methods in concert with the planned satellite usage. Network management suite modifications enable cohesive incorporation of these protection schemes. Such transitional ideas offer a smooth and planned transition as the TCA takes life.

Optimal helicopter trajectory planning for terrain following flight

NASA Technical Reports Server (NTRS)

Menon, P. K. A.

1990-01-01

Helicopters operating in high threat areas have to fly close to the earth surface to minimize the risk of being detected by the adversaries. Techniques are presented for low altitude helicopter trajectory planning. These methods are based on optimal control theory and appear to be implementable onboard in realtime. Second order necessary conditions are obtained to provide a criterion for finding the optimal trajectory when more than one extremal passes through a given point. A second trajectory planning method incorporating a quadratic performance index is also discussed. Trajectory planning problem is formulated as a differential game. The objective is to synthesize optimal trajectories in the presence of an actively maneuvering adversary. Numerical methods for obtaining solutions to these problems are outlined. As an alternative to numerical method, feedback linearizing transformations are combined with the linear quadratic game results to synthesize explicit nonlinear feedback strategies for helicopter pursuit-evasion. Some of the trajectories generated from this research are evaluated on a six-degree-of-freedom helicopter simulation incorporating an advanced autopilot. The optimal trajectory planning methods presented are also useful for autonomous land vehicle guidance.

Transforming your professional self: encouraging lifelong personal and professional growth.

PubMed

Rodts, Mary F; Lamb, Karen V

2008-01-01

Transforming from student nurse to registered nurse is often discussed in a capstone class or a hospital orientation program. Changes in professional plans later in the career continuum often occur, but are not always planned. This article discusses the challenges of change, the need for career planning, stages of role acquisition, role socialization, and role transformation. In addition, it outlines the importance of creating a career plan to meet future career goals.

Run-time parallelization and scheduling of loops

NASA Technical Reports Server (NTRS)

Saltz, Joel H.; Mirchandaney, Ravi; Crowley, Kay

1990-01-01

Run time methods are studied to automatically parallelize and schedule iterations of a do loop in certain cases, where compile-time information is inadequate. The methods presented involve execution time preprocessing of the loop. At compile-time, these methods set up the framework for performing a loop dependency analysis. At run time, wave fronts of concurrently executable loop iterations are identified. Using this wavefront information, loop iterations are reordered for increased parallelism. Symbolic transformation rules are used to produce: inspector procedures that perform execution time preprocessing and executors or transformed versions of source code loop structures. These transformed loop structures carry out the calculations planned in the inspector procedures. Performance results are presented from experiments conducted on the Encore Multimax. These results illustrate that run time reordering of loop indices can have a significant impact on performance. Furthermore, the overheads associated with this type of reordering are amortized when the loop is executed several times with the same dependency structure.

10 CFR Appendix C to Subpart C of... - Sampling Plan for Enforcement Testing of Distribution Transformers

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 3 2013-01-01 2013-01-01 false Sampling Plan for Enforcement Testing of Distribution Transformers C Appendix C to Subpart C of Part 429 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION... Testing of Distribution Transformers (a) When testing distribution transformers, the number of units in...

10 CFR Appendix C to Subpart C of... - Sampling Plan for Enforcement Testing of Distribution Transformers

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 3 2014-01-01 2014-01-01 false Sampling Plan for Enforcement Testing of Distribution Transformers C Appendix C to Subpart C of Part 429 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION... Testing of Distribution Transformers (a) When testing distribution transformers, the number of units in...

10 CFR Appendix C to Subpart C of... - Sampling Plan for Enforcement Testing of Distribution Transformers

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 3 2012-01-01 2012-01-01 false Sampling Plan for Enforcement Testing of Distribution Transformers C Appendix C to Subpart C of Part 429 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION... Testing of Distribution Transformers (a) When testing distribution transformers, the number of units in...

Connecting the Dots and Merging Meaning: Using Mixed Methods to Study Primary Care Delivery Transformation

PubMed Central

Scammon, Debra L; Tomoaia-Cotisel, Andrada; Day, Rachel L; Day, Julie; Kim, Jaewhan; Waitzman, Norman J; Farrell, Timothy W; Magill, Michael K

2013-01-01

Objective. To demonstrate the value of mixed methods in the study of practice transformation and illustrate procedures for connecting methods and for merging findings to enhance the meaning derived. Data Source/Study Setting. An integrated network of university-owned, primary care practices at the University of Utah (Community Clinics or CCs). CC has adopted Care by Design, its version of the Patient Centered Medical Home. Study Design. Convergent case study mixed methods design. Data Collection/Extraction Methods. Analysis of archival documents, internal operational reports, in-clinic observations, chart audits, surveys, semistructured interviews, focus groups, Centers for Medicare and Medicaid Services database, and the Utah All Payer Claims Database. Principal Findings. Each data source enriched our understanding of the change process and understanding of reasons that certain changes were more difficult than others both in general and for particular clinics. Mixed methods enabled generation and testing of hypotheses about change and led to a comprehensive understanding of practice change. Conclusions. Mixed methods are useful in studying practice transformation. Challenges exist but can be overcome with careful planning and persistence. PMID:24279836

Are Planning Students becoming Transformational Leaders?

ERIC Educational Resources Information Center

Nagy, Beth

2012-01-01

This research asks us to consider the intersection of three major themes in the pedagogy of teaching Planning students: sustainable community theories, transformational leadership and community engagement. The intersection, a critical Planning pedagogy, should be a part of any Planning program, embedded within the curriculum of higher education.…

Drama Improvisation as a Method of Covering Fairy Tales in School Curriculum.

ERIC Educational Resources Information Center

Sefer, Jasmina; Angelovski, Nada

In order to influence motivation and children's creativity, some attractive methods were introduced into the classical contents of the usual program of material (Serbocroatian) language and literature and other subjects in the curriculum planned for the third grade. Work on a tale was carried out in an atmosphere of slightly transformed space in…

Model Development and Process Analysis for Lean Cellular Design Planning in Aerospace Assembly and Manufacturing

NASA Astrophysics Data System (ADS)

Hilburn, Monty D.

Successful lean manufacturing and cellular manufacturing execution relies upon a foundation of leadership commitment and strategic planning built upon solid data and robust analysis. The problem for this study was to create and employ a simple lean transformation planning model and review process that could be used to identify functional support staff resources required to plan and execute lean manufacturing cells within aerospace assembly and manufacturing sites. The lean planning model was developed using available literature for lean manufacturing kaizen best practices and validated through a Delphi panel of lean experts. The resulting model and a standardized review process were used to assess the state of lean transformation planning at five sites of an international aerospace manufacturing and assembly company. The results of the three day, on-site review were compared with baseline plans collected from each of the five sites to determine if there analyzed, with focus on three critical areas of lean planning: the number and type of manufacturing cells identified, the number, type, and duration of planned lean and continuous kaizen events, and the quantity and type of functional staffing resources planned to support the kaizen schedule. Summarized data of the baseline and on-site reviews was analyzed with descriptive statistics. ANOVAs and paired-t tests at 95% significance level were conducted on the means of data sets to determine if null hypotheses related to cell, kaizen event, and support resources could be rejected. The results of the research found significant differences between lean transformation plans developed by site leadership and plans developed utilizing the structured, on-site review process and lean transformation planning model. The null hypothesis that there was no difference between the means of pre-review and on-site cell counts was rejected, as was the null hypothesis that there was no significant difference in kaizen event plans. These factors are critical inputs into the support staffing resources calculation used by the lean planning model. Null hypothesis related to functional support staff resources was rejected for most functional groups, indicating that the baseline site plan inadequately provided for cross-functional staff involvement to support the lean transformation plan. Null hypotheses related to total lean transformation staffing could not be rejected, indicating that while total staffing plans were not significantly different than plans developed during the on-site review and through the use of the lean planning model, the allocation of staffing among various functional groups such as engineering, production, and materials planning was an issue. The on-site review process and simple lean transformation plan developed was determined to be useful in identifying short-comings in lean transformation planning within aerospace manufacturing and assembly sites. It was concluded that the differences uncovered were likely contributing factors affecting the effectiveness of aerospace manufacturing sites' implementation of lean cellular manufacturing.

78 FR 1570 - Semiannual Regulatory Agenda

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-08

... Transformers (energy efficiency standards) Residential clothes washers (energy efficiency standards... Distribution Transformers (Reg Plan Seq No. 32). 263 Test Procedures for 1904-AC76 Residential Refrigerators... Efficiency Standards for Distribution Transformers Regulatory Plan: This entry is Seq. No. 32 in part II of...

Creating a future worth experiencing: nursing strategic planning in an integrated healthcare delivery system.

PubMed

Drenkard, K N

2001-01-01

The application of a strategic planning methodology for the discipline of nursing is described in use by a large, nonprofit integrated healthcare system. The methodology uses a transformational leadership assessment tool, quality planning methods, and large group intervention to engage nurses in the implementation of strategies. Based on systems theory, the methodology outlined by the author has application at any level in an organization, from an entire delivery network, to a patient care unit. The author discusses getting started on a strategic planning journey, tools that are useful in the process, integrating already existing business plans into the strategies for nursing, preliminary measures to monitor progress, and lessons learned along the journey.

Connecting the dots and merging meaning: using mixed methods to study primary care delivery transformation.

PubMed

Scammon, Debra L; Tomoaia-Cotisel, Andrada; Day, Rachel L; Day, Julie; Kim, Jaewhan; Waitzman, Norman J; Farrell, Timothy W; Magill, Michael K

2013-12-01

To demonstrate the value of mixed methods in the study of practice transformation and illustrate procedures for connecting methods and for merging findings to enhance the meaning derived. An integrated network of university-owned, primary care practices at the University of Utah (Community Clinics or CCs). CC has adopted Care by Design, its version of the Patient Centered Medical Home. Convergent case study mixed methods design. Analysis of archival documents, internal operational reports, in-clinic observations, chart audits, surveys, semistructured interviews, focus groups, Centers for Medicare and Medicaid Services database, and the Utah All Payer Claims Database. Each data source enriched our understanding of the change process and understanding of reasons that certain changes were more difficult than others both in general and for particular clinics. Mixed methods enabled generation and testing of hypotheses about change and led to a comprehensive understanding of practice change. Mixed methods are useful in studying practice transformation. Challenges exist but can be overcome with careful planning and persistence. © Health Research and Educational Trust.

Student Services Revitalization/Transformation

ERIC Educational Resources Information Center

Pipitone, Brenda; Poirer, Wayne

2011-01-01

Over a two year period, a multidisciplinary team developed and implemented a plan to transform the delivery of student services at George Brown College in Toronto. It was a plan that called upon the College to fundamentally overhaul student services, but more importantly, to transform the service culture at the College through the students'…

A Requirements Analysis for Primary Care at Womack Army Medical Center

DTIC Science & Technology

2006-06-16

posed by threats such as weapons of mass destruction and terrorism (Army Transformation Plan, 2001). The Army Transformation Plan revising European...Health Systems Specialist for Clark Health Clinic, Expansion Plan 14 personal comunication , May 2006) . Robinson Health Clinic supports the 8 2 nd

Transformation of Topic-Specific Professional Knowledge into Personal Pedagogical Content Knowledge through Lesson Planning

ERIC Educational Resources Information Center

Stender, Anita; Brückmann, Maja; Neumann, Knut

2017-01-01

This study investigates the relationship between two different types of pedagogical content knowledge (PCK): the topic-specific professional knowledge (TSPK) and practical routines, so-called teaching scripts. Based on the Transformation Model of Lesson Planning, we assume that teaching scripts originate from a transformation of TSPK during lesson…

Transformation of the California mental health system: stakeholder-driven planning as a transformational activity.

PubMed

Cashin, Cheryl; Scheffler, Richard; Felton, Mistique; Adams, Neal; Miller, Leonard

2008-10-01

This study describes strategies developed by California counties to transform their mental health systems under the 2004 Mental Health Services Act (MHSA). This voter initiative places a 1% tax on annual incomes over $1 million; tax monies are earmarked to transform county-operated mental health services into systems that are oriented more toward recovery. MHSA implementation itself can be considered "transformational" by balancing greater standardization of mental health service delivery in the state with a locally driven planning process. A qualitative content analysis of the three-year plans submitted by 12 counties to receive funds under MHSA was conducted to identify common themes, as well as innovative approaches. These 12 (out of 58) counties were chosen to represent both small and large counties, as well as geographic diversity, and they represent 62.3% of the state population. This analysis showed that the state guidelines and local planning process generated consistency across counties in establishing full-service partnerships with a "whatever it takes" approach to providing goal-directed services and supports to consumers and their families. There was, however, little convergence around the specific strategies to achieve this vision, reflecting both the local planning process and a relative lack of clear policy and guidance on evidence-based practices. There are many obstacles to the successful implementation of these ambitious plans. However, the state-guided, but stakeholder-driven, transformation in California appears to generate innovative approaches to recovery-oriented services, involve consumers and family members in service planning and delivery, and build community partnerships that create new opportunities for consumers to meet their recovery goals.

Toward frameless stereotaxy: anatomical-vascular correlation and registration

NASA Astrophysics Data System (ADS)

Henri, Christopher J.; Cukiert, A.; Collins, D. Louis; Olivier, A.; Peters, Terence M.

1992-09-01

We present a method to correlate and register a projection angiogram with volume rendered tomographic data from the same patient. Previously, we have described how this may be accomplished using a stereotactic frame to handle the required coordinate transformations. Here we examine the efficacy of employing anatomically based landmarks as opposed to external fiducials to achieve the same results. The experiments required a neurosurgeon to identify several homologous points in a DSA image and a MRI volume which were subsequently used to compute the coordinate transformations governing the matching procedure. Correlation accuracy was assessed by comparing these results to those employing fiducial markers on a stereotactic frame, and by examining how different levels of noise in the positions of the homologous points affect the resulting coordinate transformations. Further simulations suggest that this method has potential to be used in planning stereotactic procedures without the use of a frame.

Feasibility study for automatic reduction of phase change imagery

NASA Technical Reports Server (NTRS)

Nossaman, G. O.

1971-01-01

The feasibility of automatically reducing a form of pictorial aerodynamic heating data is discussed. The imagery, depicting the melting history of a thin coat of fusible temperature indicator painted on an aerodynamically heated model, was previously reduced by manual methods. Careful examination of various lighting theories and approaches led to an experimentally verified illumination concept capable of yielding high-quality imagery. Both digital and video image processing techniques were applied to reduction of the data, and it was demonstrated that either method can be used to develop superimposed contours. Mathematical techniques were developed to find the model-to-image and the inverse image-to-model transformation using six conjugate points, and methods were developed using these transformations to determine heating rates on the model surface. A video system was designed which is able to reduce the imagery rapidly, economically and accurately. Costs for this system were estimated. A study plan was outlined whereby the mathematical transformation techniques developed to produce model coordinate heating data could be applied to operational software, and methods were discussed and costs estimated for obtaining the digital information necessary for this software.

Scale invariant feature transform in adaptive radiation therapy: a tool for deformable image registration assessment and re-planning indication

NASA Astrophysics Data System (ADS)

Paganelli, Chiara; Peroni, Marta; Riboldi, Marco; Sharp, Gregory C.; Ciardo, Delia; Alterio, Daniela; Orecchia, Roberto; Baroni, Guido

2013-01-01

Adaptive radiation therapy (ART) aims at compensating for anatomic and pathological changes to improve delivery along a treatment fraction sequence. Current ART protocols require time-consuming manual updating of all volumes of interest on the images acquired during treatment. Deformable image registration (DIR) and contour propagation stand as a state of the ART method to automate the process, but the lack of DIR quality control methods hinder an introduction into clinical practice. We investigated the scale invariant feature transform (SIFT) method as a quantitative automated tool (1) for DIR evaluation and (2) for re-planning decision-making in the framework of ART treatments. As a preliminary test, SIFT invariance properties at shape-preserving and deformable transformations were studied on a computational phantom, granting residual matching errors below the voxel dimension. Then a clinical dataset composed of 19 head and neck ART patients was used to quantify the performance in ART treatments. For the goal (1) results demonstrated SIFT potential as an operator-independent DIR quality assessment metric. We measured DIR group systematic residual errors up to 0.66 mm against 1.35 mm provided by rigid registration. The group systematic errors of both bony and all other structures were also analyzed, attesting the presence of anatomical deformations. The correct automated identification of 18 patients who might benefit from ART out of the total 22 cases using SIFT demonstrated its capabilities toward goal (2) achievement.

ICT, Education Transformation, and Economic Development: An Analysis of the US National Educational Technology Plan

ERIC Educational Resources Information Center

Kozma, Robert B.

2011-01-01

In support of the conclusions and recommendations in the National Education Technology Plan (NETP), this article makes explicit the connections between the economic rationale used in the plan and the educational transformations it recommends. The article reviews macroeconomic research, microeconomic research, labor market and workforce studies,…

Going digital: a checklist in preparing for hospital-wide electronic medical record implementation and digital transformation.

PubMed

Scott, Ian A; Sullivan, Clair; Staib, Andrew

2018-05-24

Objective In an era of rapid digitisation of Australian hospitals, practical guidance is needed in how to successfully implement electronic medical records (EMRs) as both a technical innovation and a major transformative change in clinical care. The aim of the present study was to develop a checklist that clearly and comprehensively defines the steps that best prepare hospitals for EMR implementation and digital transformation. Methods The checklist was developed using a formal methodological framework comprised of: literature reviews of relevant issues; an interactive workshop involving a multidisciplinary group of digital leads from Queensland hospitals; a draft document based on literature and workshop proceedings; and a review and feedback from senior clinical leads. Results The final checklist comprised 19 questions, 13 related to EMR implementation and six to digital transformation. Questions related to the former included organisational considerations (leadership, governance, change leaders, implementation plan), technical considerations (vendor choice, information technology and project management teams, system and hardware alignment with clinician workflows, interoperability with legacy systems) and training (user training, post-go-live contingency plans, roll-out sequence, staff support at point of care). Questions related to digital transformation included cultural considerations (clinically focused vision statement and communication strategy, readiness for change surveys), management of digital disruption syndromes and plans for further improvement in patient care (post-go-live optimisation of digital system, quality and benefit evaluation, ongoing digital innovation). Conclusion This evidence-based, field-tested checklist provides guidance to hospitals planning EMR implementation and separates readiness for EMR from readiness for digital transformation. What is known about the topic? Many hospitals throughout Australia have implemented, or are planning to implement, hospital wide electronic medical records (EMRs) with varying degrees of functionality. Few hospitals have implemented a complete end-to-end digital system with the ability to bring about major transformation in clinical care. Although the many challenges in implementing EMRs have been well documented, they have not been incorporated into an evidence-based, field-tested checklist that can practically assist hospitals in preparing for EMR implementation as both a technical innovation and a vehicle for major digital transformation of care. What does this paper add? This paper outlines a 19-question checklist that was developed using a formal methodological framework comprising literature review of relevant issues, proceedings from an interactive workshop involving a multidisciplinary group of digital leads from hospitals throughout Queensland, including three hospitals undertaking EMR implementation and one hospital with complete end-to-end EMR, and review of a draft checklist by senior clinical leads within a statewide digital healthcare improvement network. The checklist distinguishes between issues pertaining to EMR as a technical innovation and EMR as a vehicle for digital transformation of patient care. What are the implications for practitioners? Successful implementation of a hospital-wide EMR requires senior managers, clinical leads, information technology teams and project management teams to fully address key operational and strategic issues. Using an issues checklist may help prevent any one issue being inadvertently overlooked or underemphasised in the planning and implementation stages, and ensure the EMR is fully adopted and optimally used by clinician users in an ongoing digital transformation of care.

An appraisal of statistical procedures used in derivation of reference intervals.

PubMed

Ichihara, Kiyoshi; Boyd, James C

2010-11-01

When conducting studies to derive reference intervals (RIs), various statistical procedures are commonly applied at each step, from the planning stages to final computation of RIs. Determination of the necessary sample size is an important consideration, and evaluation of at least 400 individuals in each subgroup has been recommended to establish reliable common RIs in multicenter studies. Multiple regression analysis allows identification of the most important factors contributing to variation in test results, while accounting for possible confounding relationships among these factors. Of the various approaches proposed for judging the necessity of partitioning reference values, nested analysis of variance (ANOVA) is the likely method of choice owing to its ability to handle multiple groups and being able to adjust for multiple factors. Box-Cox power transformation often has been used to transform data to a Gaussian distribution for parametric computation of RIs. However, this transformation occasionally fails. Therefore, the non-parametric method based on determination of the 2.5 and 97.5 percentiles following sorting of the data, has been recommended for general use. The performance of the Box-Cox transformation can be improved by introducing an additional parameter representing the origin of transformation. In simulations, the confidence intervals (CIs) of reference limits (RLs) calculated by the parametric method were narrower than those calculated by the non-parametric approach. However, the margin of difference was rather small owing to additional variability in parametrically-determined RLs introduced by estimation of parameters for the Box-Cox transformation. The parametric calculation method may have an advantage over the non-parametric method in allowing identification and exclusion of extreme values during RI computation.

Reflections on the Draft National Educational Technology Plan 2010: Foundations for Transformation

ERIC Educational Resources Information Center

Dede, Chris

2010-01-01

This article provides personal reflections about aspects of the draft "National Educational Technology Plan 2010". Its focus is on ideas in the Plan that could be foundational for transforming our industrial-era schooling system. In sharing these thoughts, the author is speaking only for himself: they do not necessarily reflect the discussions or…

The National Educational Technology Plan Doesn't Live up to Its Call for Revolutionary Transformation

ERIC Educational Resources Information Center

Rose, Raymond M.

2011-01-01

The National Educational Technology Plan (NETP) calls for the revolutionary transformation of the American educational system. The plan correctly points to the decisions of the late 1800s that still direct educational policy today, and correctly calls the school change efforts evolutionary tinkering. The author, a pioneer in online education…

Exploration of Potential Future Fleet Architectures

DTIC Science & Technology

2005-07-01

alternative architectures are those espoused by the OFT sponsoring office: flexibility, adaptability, agility, speed, and information dominance through...including naval forces, which we used. The OFT advocates flexibility, adaptability, agility, speed, and information dominance through networking...challenges and transnational threats. In future conflicts, the Navy has plans to expand strike power, realize information dominance , and transform methods

10. Photographic copy of drawing dated January 22, 1908 (Source: ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. Photographic copy of drawing dated January 22, 1908 (Source: Salt River Project) General plans, index to detail plans and sections, transformer house - Theodore Roosevelt Dam, Transformer House, Salt River, Tortilla Flat, Maricopa County, AZ

The Road Less Travelled: The Deep Challenges of Social Transformations

NASA Astrophysics Data System (ADS)

O'Brien, K. L.; Moser, S. C.

2016-12-01

How do we create the societal transformations necessary to stabilize the global climate and address other global goals? The roadmap metaphor guiding this session reflects a managerial approach to deep decarbonization, one that can be planned, charted, guided and implemented with the tools already known. Transformations and systems change involve far more than technical innovations, policy instruments and behavioral change. Drawing on a wide range of research on transformation processes from the social sciences and humanities and systems science, we argue that current approaches to decarbonization are likely to fail if they ignore theories of social change, including insights on the dynamics of social, cultural, economic and political transformations. Climate stabilization also calls for attention to the relationships between human values, political agency, power, and institutional change. It is precisely these deeper dynamics - which are typically ignored - that stall transformative change. Rather than developing a carbon road map, we suggest both a wider and deeper exploration of the territory of social transformation is needed, and suggest both different metaphors and methods to engage individual change agents and communities of actors, who together can create pathways to sustainability.

Design, development and clinical validation of computer-aided surgical simulation system for streamlined orthognathic surgical planning

PubMed Central

Yuan, Peng; Mai, Huaming; Li, Jianfu; Ho, Dennis Chun-Yu; Lai, Yingying; Liu, Siting; Kim, Daeseung; Xiong, Zixiang; Alfi, David M.; Teichgraeber, John F.; Gateno, Jaime

2017-01-01

Purpose There are many proven problems associated with traditional surgical planning methods for orthognathic surgery. To address these problems, we developed a computer-aided surgical simulation (CASS) system, the AnatomicAligner, to plan orthognathic surgery following our streamlined clinical protocol. Methods The system includes six modules: image segmentation and three-dimensional (3D) reconstruction, registration and reorientation of models to neutral head posture, 3D cephalometric analysis, virtual osteotomy, surgical simulation, and surgical splint generation. The accuracy of the system was validated in a stepwise fashion: first to evaluate the accuracy of AnatomicAligner using 30 sets of patient data, then to evaluate the fitting of splints generated by AnatomicAligner using 10 sets of patient data. The industrial gold standard system, Mimics, was used as the reference. Result When comparing the results of segmentation, virtual osteotomy and transformation achieved with AnatomicAligner to the ones achieved with Mimics, the absolute deviation between the two systems was clinically insignificant. The average surface deviation between the two models after 3D model reconstruction in AnatomicAligner and Mimics was 0.3 mm with a standard deviation (SD) of 0.03 mm. All the average surface deviations between the two models after virtual osteotomy and transformations were smaller than 0.01 mm with a SD of 0.01 mm. In addition, the fitting of splints generated by AnatomicAligner was at least as good as the ones generated by Mimics. Conclusion We successfully developed a CASS system, the AnatomicAligner, for planning orthognathic surgery following the streamlined planning protocol. The system has been proven accurate. AnatomicAligner will soon be available freely to the boarder clinical and research communities. PMID:28432489

Multiresolution motion planning for autonomous agents via wavelet-based cell decompositions.

PubMed

Cowlagi, Raghvendra V; Tsiotras, Panagiotis

2012-10-01

We present a path- and motion-planning scheme that is "multiresolution" both in the sense of representing the environment with high accuracy only locally and in the sense of addressing the vehicle kinematic and dynamic constraints only locally. The proposed scheme uses rectangular multiresolution cell decompositions, efficiently generated using the wavelet transform. The wavelet transform is widely used in signal and image processing, with emerging applications in autonomous sensing and perception systems. The proposed motion planner enables the simultaneous use of the wavelet transform in both the perception and in the motion-planning layers of vehicle autonomy, thus potentially reducing online computations. We rigorously prove the completeness of the proposed path-planning scheme, and we provide numerical simulation results to illustrate its efficacy.

A Long-Term Model for the Curriculum of Training for an Electric-Power Specialist

ERIC Educational Resources Information Center

Venikov, V. A.

1978-01-01

Long-term planning for professional training of electric-power specialists in Russia will have to (1) recognize the need for specialists to adapt to unforeseen developments in the field, (2) include new mathematics, physics, and computer technology, and (3) be prepared for changes in methods of production and transformation of energy. (AV)

77 FR 35395 - Draft Five-Year Plan (2013-2017) for the National Toxicology Program Interagency Center for the...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-13

... innovations are driving transformative changes in toxicology and how safety testing is performed. The field of toxicology is evolving from a system based largely on animal testing toward one based on the integration of... methods that protect human and animal health and the environment while reducing, refining (enhancing...

An accurate segmentation method for volumetry of brain tumor in 3D MRI

NASA Astrophysics Data System (ADS)

Wang, Jiahui; Li, Qiang; Hirai, Toshinori; Katsuragawa, Shigehiko; Li, Feng; Doi, Kunio

2008-03-01

Accurate volumetry of brain tumors in magnetic resonance imaging (MRI) is important for evaluating the interval changes in tumor volumes during and after treatment, and also for planning of radiation therapy. In this study, an automated volumetry method for brain tumors in MRI was developed by use of a new three-dimensional (3-D) image segmentation technique. First, the central location of a tumor was identified by a radiologist, and then a volume of interest (VOI) was determined automatically. To substantially simplify tumor segmentation, we transformed the 3-D image of the tumor into a two-dimensional (2-D) image by use of a "spiral-scanning" technique, in which a radial line originating from the center of the tumor scanned the 3-D image spirally from the "north pole" to the "south pole". The voxels scanned by the radial line provided a transformed 2-D image. We employed dynamic programming to delineate an "optimal" outline of the tumor in the transformed 2-D image. We then transformed the optimal outline back into 3-D image space to determine the volume of the tumor. The volumetry method was trained and evaluated by use of 16 cases with 35 brain tumors. The agreement between tumor volumes provided by computer and a radiologist was employed as a performance metric. Our method provided relatively accurate results with a mean agreement value of 88%.

[Teaching methods for clinical settings: a literature review].

PubMed

Brugnolli, Anna; Benaglio, Carla

2017-01-01

. Teaching Methods for clinical settings: a review. The teaching process during internship requires several methods to promote the acquisition of more complex technical skills such as relational, decisional and planning abilities. To describe effective teaching methods to promote the learning of relational, decisional and planning skills. A literature review of the teaching methods that have proven most effective, most appreciated by students, and most frequently used in Italian nursing schools. Clinical teaching is a central element to transform clinical experiences during internship in professional competences. The students are gradually brought to become more independent, because they are offered opportunities to practice in real contexts, to receive feedback, to have positive role models, to become more autonomous: all elements that facilitate and potentiate learning. Clinical teaching should be based on a variety of methods. The students value a gradual progression both in clinical experiences and teaching strategies from more supervised methods to methods more oriented towards reflecting on clinical practice and self-directed learning.

Integrated planning for regional development planning and water resources management under uncertainty: A case study of Xining, China

NASA Astrophysics Data System (ADS)

Fu, Z. H.; Zhao, H. J.; Wang, H.; Lu, W. T.; Wang, J.; Guo, H. C.

2017-11-01

Economic restructuring, water resources management, population planning and environmental protection are subjects to inner uncertainties of a compound system with objectives which are competitive alternatives. Optimization model and water quality model are usually used to solve problems in a certain aspect. To overcome the uncertainty and coupling in reginal planning management, an interval fuzzy program combined with water quality model for regional planning and management has been developed to obtain the absolutely ;optimal; solution in this study. The model is a hybrid methodology of interval parameter programming (IPP), fuzzy programing (FP), and a general one-dimensional water quality model. The method extends on the traditional interval parameter fuzzy programming method by integrating water quality model into the optimization framework. Meanwhile, as an abstract concept, water resources carrying capacity has been transformed into specific and calculable index. Besides, unlike many of the past studies about water resource management, population as a significant factor has been considered. The results suggested that the methodology was applicable for reflecting the complexities of the regional planning and management systems within the planning period. The government policy makers could establish effective industrial structure, water resources utilization patterns and population planning, and to better understand the tradeoffs among economic, water resources, population and environmental objectives.

Poster - Thur Eve - 77: Coordinate transformation from DICOM to DOSXYZnrc.

PubMed

Zhan, L; Jiang, R; Osei, E K

2012-07-01

DICOM format is the de facto standard for communications between therapeutic and diagnostic modalities. A plan generated by a treatment planning system (TPS) is often exported to DICOM format. BEAMnrc/DOSXYZnrc is a widely used Monte Carlo (MC) package for beam and dose simulations in radiotherapy. It has its own definition for beam orientation, which is not in compliance with the one defined in DICOM standard. Dose simulations using TPS generated plans require transformation of beam orientations to DOSXYZnrc coordinate system (c.s.) after extracting the necessary parameters from DICOM RP files. The transformation is nontrivial. There have been two studies for the coordinate transformations. The transformation equation sets derived have been helpful to BEAMnrc/DOSXYZnrc users. However, both the transformation equation sets are complex mathematically and not easy to program. In this study, we derive a new set of transformation equations, which are more compact, better understandable, and easier for computational implementation. The derivation of polar angle θ and azimuthal angle φ is similar to the existing studies by applying a series of rotations to a vector in DICOM patient c.s. The derivation of beam rotation Φ col for DOSXYZnrc, however, is different. It is obtained by a direct combination of the actual collimator rotation with the projection of the couch rotation to the collimator rotating plane. Verification of the transformation has been performed using clinical plans created with Eclipse. The comparison between Eclipse and MC results show exact geometrical agreement for field placements, together with good agreement in dose distributions. © 2012 American Association of Physicists in Medicine.

Beam coordinate transformations from DICOM to DOSXYZnrc

NASA Astrophysics Data System (ADS)

Zhan, Lixin; Jiang, Runqing; Osei, Ernest K.

2012-12-01

Digital imaging and communications in medicine (DICOM) format is the de facto standard for communications between therapeutic and diagnostic modalities. A plan generated by a treatment planning system (TPS) is often exported in DICOM format. BEAMnrc/DOSXYZnrc is a widely used Monte Carlo (MC) package for modelling the Linac head and simulating dose delivery in radiotherapy. It has its own definition of beam orientation, which is not in compliance with the one defined in the DICOM standard. MC dose calculations using information from TPS generated plans require transformation of beam orientations to the DOSXYZnrc coordinate system (c.s.) and the transformation is non-trivial. There have been two studies on the coordinate transformations. The transformation equation sets derived have been helpful to BEAMnrc/DOSXYZnrc users. However, the transformation equation sets are complex mathematically and not easy to program. In this study, we derive a new set of transformation equations, which are more compact, easily understandable, and easier for computational implementation. The derivation of the polar angle θ and the azimuthal angle φ used by DOSXYZnrc is similar to the existing studies by applying a series of rotations to a vector in DICOM patient c.s. The derivation of the beam rotation ϕcol for DOSXYZnrc, however, is different. It is obtained by a direct combination of the actual collimator rotation with the projection of the couch rotation to the collimator rotating plane. Verification of the transformation has been performed using clinical plans. The comparisons between TPS and MC results show very good geometrical agreement for field placements, together with good agreement in dose distributions.

Efficient Digital Implementation of The Sigmoidal Function For Artificial Neural Network

NASA Astrophysics Data System (ADS)

Pratap, Rana; Subadra, M.

2011-10-01

An efficient piecewise linear approximation of a nonlinear function (PLAN) is proposed. This uses simulink environment design to perform a direct transformation from X to Y, where X is the input and Y is the approximated sigmoidal output. This PLAN is then used within the outputs of an artificial neural network to perform the nonlinear approximation. In This paper, is proposed a method to implement in FPGA (Field Programmable Gate Array) circuits different approximation of the sigmoid function.. The major benefit of the proposed method resides in the possibility to design neural networks by means of predefined block systems created in System Generator environment and the possibility to create a higher level design tools used to implement neural networks in logical circuits.

Opportunities and challenges of resident specialists’ attendance plan guidelines (health-care transformation plan) in Isfahan university hospitals in 2015

PubMed Central

Moradi, Reza; Karimi, Saeid; Yarmohammadian, Mohammad Hossein; Kiaei, Mohammad Zakaria; Mazaheri, Elaheh

2018-01-01

BACKGROUND: Given new reforms in Iran's health-care system and due to the need for gathering evidence regarding the implementation of this plan, this study aimed to investigate opportunities and challenges created by resident specialist attendance plan guidelines in university hospitals. MATERIALS AND METHODS: This study used the qualitative method. Semi-structured interviews were used for data gathering. The study population included all experts of Isfahan University of Medical Science. Sampling was carried out using purposeful sampling method and continued until data saturation was reached. In total, 16 experts were interviewed. Criteria such as “reliability of information,” “trustworthiness,” and “verifiability of the information” were considered. Interviewees were assured that their names would keep hidden and that all information is confidential. Subject analysis method was used for data analysis. RESULTS: The findings of this study based on subject analysis led to extracting three themes in regards of challenges in the implementation of resident (specialist or fellowship) plan in hospitals including structural, management, and resource challenges and one theme in the area of opportunities which were improved quality and timely provision of services. CONCLUSION: The findings showed that despite the strengths of this guideline, there are some fundamental challenges in various areas and need better attention by national level policymakers. These results help health-care policymakers to evaluate the problem with a better attitude and improve the necessary plans for implementation of these guidelines. PMID:29619390

Youth Engaging Language Policy and Planning: Ideologies and Transformations from Within

ERIC Educational Resources Information Center

Phyak, Prem; Bui, Thuy Thi Ngoc

2014-01-01

This paper explores language policy and planning from the perspectives of global ideologies, national agendas, and local transformation in two Asian countries, Vietnam and Nepal. Through engaged ethnography, we not only unravel complex ideological contestations of neoliberal and nationalistic agendas, but also portray language policy resistance…

From Spoke to Hub: Transforming Organizational Vision and Strategy With Story and Visual Art

ERIC Educational Resources Information Center

Tyler, Jo A.

2015-01-01

This article reports on a case study at an inner-city nonprofit service agency that inquired into the ways integration of storytelling and visual art as a method of adult learning and way of knowing might influence the process of strategic visioning and planning in a nonprofit organization. The case study focuses on data collected through…

Automated planning of MRI scans of knee joints

NASA Astrophysics Data System (ADS)

Bystrov, Daniel; Pekar, Vladimir; Young, Stewart; Dries, Sebastian P. M.; Heese, Harald S.; van Muiswinkel, Arianne M.

2007-03-01

A novel and robust method for automatic scan planning of MRI examinations of knee joints is presented. Clinical knee examinations require acquisition of a 'scout' image, in which the operator manually specifies the scan volume orientations (off-centres, angulations, field-of-view) for the subsequent diagnostic scans. This planning task is time-consuming and requires skilled operators. The proposed automated planning system determines orientations for the diagnostic scan by using a set of anatomical landmarks derived by adapting active shape models of the femur, patella and tibia to the acquired scout images. The expert knowledge required to position scan geometries is learned from previous manually planned scans, allowing individual preferences to be taken into account. The system is able to automatically discriminate between left and right knees. This allows to use and merge training data from both left and right knees, and to automatically transform all learned scan geometries to the side for which a plan is required, providing a convenient integration of the automated scan planning system in the clinical routine. Assessment of the method on the basis of 88 images from 31 different individuals, exhibiting strong anatomical and positional variability demonstrates success, robustness and efficiency of all parts of the proposed approach, which thus has the potential to significantly improve the clinical workflow.

Goal programming for land use planning.

Treesearch

Enoch F. Bell

1976-01-01

A simple transformation of the linear programing model used in land use planning to a goal programing model allows the multiple goals implied by multiple use management to be explicitly recognized. This report outlines the procedure for accomplishing the transformation and discusses problems with use of goal programing. Of particular concern are the expert opinions...

Full two-dimensional transient solutions of electrothermal aircraft blade deicing

NASA Technical Reports Server (NTRS)

Masiulaniec, K. C.; Keith, T. G., Jr.; Dewitt, K. J.; Leffel, K. L.

1985-01-01

Two finite difference methods are presented for the analysis of transient, two-dimensional responses of an electrothermal de-icer pad of an aircraft wing or blade with attached variable ice layer thickness. Both models employ a Crank-Nicholson iterative scheme, and use an enthalpy formulation to handle the phase change in the ice layer. The first technique makes use of a 'staircase' approach, fitting the irregular ice boundary with square computational cells. The second technique uses a body fitted coordinate transform, and maps the exact shape of the irregular boundary into a rectangular body, with uniformally square computational cells. The numerical solution takes place in the transformed plane. Initial results accounting for variable ice layer thickness are presented. Details of planned de-icing tests at NASA-Lewis, which will provide empirical verification for the above two methods, are also presented.

Maintaining an expert system for the Hubble Space Telescope ground support

NASA Technical Reports Server (NTRS)

Lindenmayer, Kelly; Vick, Shon; Rosenthal, Don

1987-01-01

The transformation portion of the Hubble Space Telescope (HST) Proposal Entry Processor System converts astronomer-oriented description of a scientific observing program into a detailed description of the parameters needed for planning and scheduling. The transformation system is one of a very few rulebased expert systems that has ever entered an operational phase. The day to day operations of the system and its rulebase are no longer the responsibility of the original developer. As a result, software engineering properties of the rulebased approach become more important. Maintenance issues associated with the coupling of rules within a rulebased system are discussed and a method is offered for partitioning a rulebase so that the amount of knowledge needed to modify the rulebase is minimized. This method is also used to develop a measure of the coupling strength of the rulebase.

Planned residential units: New development trajectories

NASA Astrophysics Data System (ADS)

Fedchenko, Irina

2017-01-01

The paper summarizes the transformation patterns of functional, morphological, social, and administrative structures of planned residential units - district (Russia, Eastern Europe), neighborhood (USA), community (UK, Europe), as the smallest structural and planning elements of the settlements. The study is based on the author's own on-site survey of the existing and new planned residential units, as well as on the analysis of theoretical sources. The multidisciplinary analysis of the theoretical concepts and on-site survey results showed that planned residential units formed in the early twentieth century retain their social and planning importance and identity, evolve and acquire new features and forms. At the same time, according to the current regulatory and legal instruments they remain basic planning elements of urban structure in the early twenty-first century. This paper also includes experimental analysis of the theoretical concepts of planned residential units' transformation, their conceptual planning model and formation principles in the early twenty-first century.

Transforming User Needs into Functional Requirements for an Antibiotic Clinical Decision Support System

PubMed Central

Bright, T.J.

2013-01-01

Summary Background Many informatics studies use content analysis to generate functional requirements for system development. Explication of this translational process from qualitative data to functional requirements can strengthen the understanding and scientific rigor when applying content analysis in informatics studies. Objective To describe a user-centered approach transforming emergent themes derived from focus group data into functional requirements for informatics solutions and to illustrate these methods to the development of an antibiotic clinical decision support system (CDS). Methods The approach consisted of five steps: 1) identify unmet therapeutic planning information needs via Focus Group Study-I, 2) develop a coding framework of therapeutic planning themes to refine the domain scope to antibiotic therapeutic planning, 3) identify functional requirements of an antibiotic CDS system via Focus Group Study-II, 4) discover informatics solutions and functional requirements from coded data, and 5) determine the types of information needed to support the antibiotic CDS system and link with the identified informatics solutions and functional requirements. Results The coding framework for Focus Group Study-I revealed unmet therapeutic planning needs. Twelve subthemes emerged and were clustered into four themes; analysis indicated a need for an antibiotic CDS intervention. Focus Group Study-II included five types of information needs. Comments from the Barrier/Challenge to information access and Function/Feature themes produced three informatics solutions and 13 functional requirements of an antibiotic CDS system. Comments from the Patient, Institution, and Domain themes generated required data elements for each informatics solution. Conclusion This study presents one example explicating content analysis of focus group data and the analysis process to functional requirements from narrative data. Illustration of this 5-step method was used to develop an antibiotic CDS system, resolving unmet antibiotic prescribing needs. As a reusable approach, these techniques can be refined and applied to resolve unmet information needs with informatics interventions in additional domains. PMID:24454586

Investigating the Impact of NGSS-Aligned Professional Development on PreK-3 Teachers' Science Content Knowledge and Pedagogy

ERIC Educational Resources Information Center

Tuttle, Nicole; Kaderavek, Joan N.; Molitor, Scott; Czerniak, Charlene M.; Johnson-Whitt, Eugenia; Bloomquist, Debra; Namatovu, Winnifred; Wilson, Grant

2016-01-01

This pilot study investigates the impact of a 2-week professional development Summer Institute on PK-3 teachers' knowledge and practices. This Summer Institute is a component of [program], a large-scale early-childhood science project that aims to transform PK-3 science teaching. The mixed-methods study examined concept maps, lesson plans, and…

10 CFR 429.47 - Distribution transformers.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 3 2014-01-01 2014-01-01 false Distribution transformers. 429.47 Section 429.47 Energy... COMMERCIAL AND INDUSTRIAL EQUIPMENT Certification § 429.47 Distribution transformers. (a) Sampling plan for selection of units for testing. (1) The requirements of § 429.11 are applicable to distribution transformers...

10 CFR 429.47 - Distribution transformers.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 3 2013-01-01 2013-01-01 false Distribution transformers. 429.47 Section 429.47 Energy... COMMERCIAL AND INDUSTRIAL EQUIPMENT Certification § 429.47 Distribution transformers. (a) Sampling plan for selection of units for testing. (1) The requirements of § 429.11 are applicable to distribution transformers...

10 CFR 429.47 - Distribution transformers.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 3 2012-01-01 2012-01-01 false Distribution transformers. 429.47 Section 429.47 Energy... COMMERCIAL AND INDUSTRIAL EQUIPMENT Certification § 429.47 Distribution transformers. (a) Sampling plan for selection of units for testing. (1) The requirements of § 429.11 are applicable to distribution transformers...

Fuzzy robust credibility-constrained programming for environmental management and planning.

PubMed

Zhang, Yimei; Hang, Guohe

2010-06-01

In this study, a fuzzy robust credibility-constrained programming (FRCCP) is developed and applied to the planning for waste management systems. It incorporates the concepts of credibility-based chance-constrained programming and robust programming within an optimization framework. The developed method can reflect uncertainties presented as possibility-density by fuzzy-membership functions. Fuzzy credibility constraints are transformed to the crisp equivalents with different credibility levels, and ordinary fuzzy inclusion constraints are determined by their robust deterministic constraints by setting a-cut levels. The FRCCP method can provide different system costs under different credibility levels (lambda). From the results of sensitivity analyses, the operation cost of the landfill is a critical parameter. For the management, any factors that would induce cost fluctuation during landfilling operation would deserve serious observation and analysis. By FRCCP, useful solutions can be obtained to provide decision-making support for long-term planning of solid waste management systems. It could be further enhanced through incorporating methods of inexact analysis into its framework. It can also be applied to other environmental management problems.

Behavioral and social sciences at the National Institutes of Health: Methods, measures, and data infrastructures as a scientific priority.

PubMed

Riley, William T

2017-01-01

The National Institutes of Health Office of Behavioral and Social Sciences Research (OBSSR) recently released its strategic plan for 2017-2021. This plan focuses on three equally important strategic priorities: 1) improve the synergy of basic and applied behavioral and social sciences research, 2) enhance and promote the research infrastructure, methods, and measures needed to support a more cumulative and integrated approach to behavioral and social sciences research, and 3) facilitate the adoption of behavioral and social sciences research findings in health research and in practice. This commentary focuses on scientific priority two and future directions in measurement science, technology, data infrastructure, behavioral ontologies, and big data methods and analytics that have the potential to transform the behavioral and social sciences into more cumulative, data rich sciences that more efficiently build on prior research. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Transforming School Leadership and Management to Support Student Learning and Development: The Field Guide to Comer Schools in Action

ERIC Educational Resources Information Center

Joyner, Edward T., Ed.; Ben-Avie, Michael, Ed.; Comer, James P., Ed.

2004-01-01

For more than 35 years, the Yale School Development Program (SDP) has been pioneering the Comer Process for planned change in schools. From initial planning and preparation, through foundation building, transformation, institutionalization, and renewal, the Comer Process provides school leaders with a comprehensive and effective framework for…

Defense Business Transformation: A Comprehensive Plan, Integrated Efforts, and Sustained Leadership are Needed to Assure Success

DTIC Science & Technology

2006-11-16

most of DOD’s major business operations. DOD’s failure to effectively resolve these high-risk areas has resulted in billions of dollars of waste each...integrated, enterprise-wide business transformation plan and its related leadership approach, and (2) comply with legislation that addresses business systems

National Research Council Dialogue to Assess Progress on NASA's Transformational Spaceport and Range Technologies Capability Roadmap Development: General Background and Introduction

NASA Technical Reports Server (NTRS)

Skelly, Darin M.

2005-01-01

Viewgraphs on the National Research Council's diaglog to assess progress on NASA's transformational spaceport and range technologies capability roadmap development is presented. The topics include: 1) Agency Goals and Objectives; 2) Strategic Planning Transformation; 3) Advanced Planning Organizational Roles; 4) Public Involvement in Strategic Planning; 5) Strategic Roadmaps; 6) Strategic Roadmaps Schedule; 7) Capability Roadmaps; 8) Capability Charter; 9) Process for Team Selection; 10) Capability Roadmap Development Schedule Overview; 11) Purpose of NRC Review; 12) Technology Readiness Levels; 13) Capability Readiness Levels; 14) Crosswalk Matrix Trans Spaceport & Range; 15) Example linkage to other roadmaps; 16) Capability Readiness Levels Defined; and 17) Crosswalk Matrix Ratings Work In-progress.

Managing change isn't good enough.

PubMed

South, S F

1999-01-01

One lesson learned from past reengineering is that to be successful in the next decade, organizations will need to create and lead transformation, not just manage the process. Two critical aspects of transformation are that it is a process and that it requires leadership. The "five Cs" of transformation are imperative: create the vision, create the plan, communicate the vision and the plan, cultivate motivated and empowered stakeholders, and cement change in the organization's culture. Business skills, the ability to lead others, and the ability to forge and maintain relationships are needed for effective leadership. For successful transformation, businesses must avoid the mistakes made in the past decade, including too much complacency, too little and/or inappropriate communication, and underestimating the importance of vision and leadership to the transformation effort.

Medical Home Transformation in Pediatric Primary Care—What Drives Change?

PubMed Central

McAllister, Jeanne W.; Cooley, W. Carl; Van Cleave, Jeanne; Boudreau, Alexy Arauz; Kuhlthau, Karen

2013-01-01

PURPOSE The aim of this study was to characterize essential factors to the medical home transformation of high-performing pediatric primary care practices 6 to 7 years after their participation in a national medical home learning collaborative. METHODS We evaluated the 12 primary care practice teams having the highest Medical Home Index (MHI) scores after participation in a national medical home learning collaborative with current MHI scores, a clinician staff questionnaire (assessing adaptive reserve), and semistructured interviews. We reviewed factors that emerged from interviews and analyzed domains and subdomains for their agreement with MHI and adaptive reserve domains and subthemes using a process of triangulation. RESULTS At 6 to 7 years after learning collaborative participation, 4 essential medical home attributes emerged as drivers of transformation: (1) a culture of quality improvement, (2) family-centered care with parents as improvement partners, (3) team-based care, and (4) care coordination. These high-performing practices developed comprehensive, family-centered, planned care processes including flexible access options, population approaches, and shared care plans. Eleven practices evolved to employ care coordinators. Family satisfaction appeared to stem from better access, care, and safety, and having a strong relationship with their health care team. Physician and staff satisfaction was high even while leadership activities strained personal time. CONCLUSIONS Participation in a medical home learning collaborative stimulated, but did not complete, medical home changes in 12 pediatric practices. Medical home transformation required continuous development, ongoing quality improvement, family partnership skills, an attitude of teamwork, and strong care coordination functions. PMID:23690392

11. Photographic copy of drawing dated February 17, 1908 (Source: ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. Photographic copy of drawing dated February 17, 1908 (Source: Salt River Project) Transformer building, first floor plan and sections (Transformer floor) - Theodore Roosevelt Dam, Transformer House, Salt River, Tortilla Flat, Maricopa County, AZ

A Rural Transformation Model: The facts of rural development in the Surakarta Metropolitan Region

NASA Astrophysics Data System (ADS)

Puspa Sari, D. P.; Asyifa, I.; Derman, I. F.; Jayanti, D. R.; Hanatya, F. Y.

2018-05-01

Not only cities are entering the urban age but suburban villages are also feeling the impact of this global phenomenon. In Indonesia, the uncontrolled rural transformation has had some negative impacts because of the unpreparedness of various aspects such as land conversion, the emergence of the informal sector, and crime. This phenomenon is often referred to as developmental externalities that need to be anticipated in planning and controlling the growth of cities and villages. This inevitable rural transformation also occurs in the Surakarta Metropolitan Region. The previous rural transformation studies in the Surakarta Metropolitan Region are based on economic, spatial to socio-ecological perspectives and are still rarely studied from the perspective of urban studies. This article aims to examine the model of rural transformation in the Surakarta Metropolitan Region based on the Rural-Urban Transformation theory by Lo, Shalih & Douglass (1998), especially in the Simo, Sambi, Ngemplak, and Nogosari Sub-districts in Boyolali District. The qualitative methods consisting of interviews, 150 questionnaires, and field observations in 2017 and literature study were used for the discussion in this article. The rural to urban transformation of the Surakarta Metropolitan Region follows the Southeast Asian Model. This research opens a new discussion on how to create a sustainable city system in the Surakarta Metropolitan Region.

A novel rail defect detection method based on undecimated lifting wavelet packet transform and Shannon entropy-improved adaptive line enhancer

NASA Astrophysics Data System (ADS)

Hao, Qiushi; Zhang, Xin; Wang, Yan; Shen, Yi; Makis, Viliam

2018-07-01

Acoustic emission (AE) technology is sensitive to subliminal rail defects, however strong wheel-rail contact rolling noise under high-speed condition has gravely impeded detecting of rail defects using traditional denoising methods. In this context, the paper develops an adaptive detection method for rail cracks, which combines multiresolution analysis with an improved adaptive line enhancer (ALE). To obtain elaborate multiresolution information of transient crack signals with low computational cost, lifting scheme-based undecimated wavelet packet transform is adopted. In order to feature the impulsive property of crack signals, a Shannon entropy-improved ALE is proposed as a signal enhancing approach, where Shannon entropy is introduced to improve the cost function. Then a rail defect detection plan based on the proposed method for high-speed condition is put forward. From theoretical analysis and experimental verification, it is demonstrated that the proposed method has superior performance in enhancing the rail defect AE signal and reducing the strong background noise, offering an effective multiresolution approach for rail defect detection under high-speed and strong-noise condition.

Research on optimal path planning algorithm of task-oriented optical remote sensing satellites

NASA Astrophysics Data System (ADS)

Liu, Yunhe; Xu, Shengli; Liu, Fengjing; Yuan, Jingpeng

2015-08-01

GEO task-oriented optical remote sensing satellite, is very suitable for long-term continuous monitoring and quick access to imaging. With the development of high resolution optical payload technology and satellite attitude control technology, GEO optical remote sensing satellites will become an important developing trend for aerospace remote sensing satellite in the near future. In the paper, we focused on GEO optical remote sensing satellite plane array stare imaging characteristics and real-time leading mission of earth observation mode, targeted on satisfying needs of the user with the minimum cost of maneuver, and put forward the optimal path planning algorithm centered on transformation from geographic coordinate space to Field of plane, and finally reduced the burden of the control system. In this algorithm, bounded irregular closed area on the ground would be transformed based on coordinate transformation relations in to the reference plane for field of the satellite payload, and then using the branch and bound method to search for feasible solutions, cutting off the non-feasible solution in the solution space based on pruning strategy; and finally trimming some suboptimal feasible solutions based on the optimization index until a feasible solution for the global optimum. Simulation and visualization presentation software testing results verified the feasibility and effectiveness of the strategy.

A spatially encoded dose difference maximal intensity projection map for patient dose evaluation: A new first line patient quality assurance tool

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hu Weigang; Graff, Pierre; Boettger, Thomas

2011-04-15

Purpose: To develop a spatially encoded dose difference maximal intensity projection (DD-MIP) as an online patient dose evaluation tool for visualizing the dose differences between the planning dose and dose on the treatment day. Methods: Megavoltage cone-beam CT (MVCBCT) images acquired on the treatment day are used for generating the dose difference index. Each index is represented by different colors for underdose, acceptable, and overdose regions. A maximal intensity projection (MIP) algorithm is developed to compress all the information of an arbitrary 3D dose difference index into a 2D DD-MIP image. In such an algorithm, a distance transformation is generatedmore » based on the planning CT. Then, two new volumes representing the overdose and underdose regions of the dose difference index are encoded with the distance transformation map. The distance-encoded indices of each volume are normalized using the skin distance obtained on the planning CT. After that, two MIPs are generated based on the underdose and overdose volumes with green-to-blue and green-to-red lookup tables, respectively. Finally, the two MIPs are merged with an appropriate transparency level and rendered in planning CT images. Results: The spatially encoded DD-MIP was implemented in a dose-guided radiotherapy prototype and tested on 33 MVCBCT images from six patients. The user can easily establish the threshold for the overdose and underdose. A 3% difference between the treatment and planning dose was used as the threshold in the study; hence, the DD-MIP shows red or blue color for the dose difference >3% or {<=}3%, respectively. With such a method, the overdose and underdose regions can be visualized and distinguished without being overshadowed by superficial dose differences. Conclusions: A DD-MIP algorithm was developed that compresses information from 3D into a single or two orthogonal projections while hinting the user whether the dose difference is on the skin surface or deeper.« less

SU-F-T-527: A Novel Dynamic Multileaf Collimator Leaf-Sequencing Algorithm in Radiation Therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jing, J; Lin, H; Chow, J

Purpose: A novel leaf-sequencing algorithm is developed for generating arbitrary beam intensity profiles in discrete levels using dynamic multileaf collimator (MLC). The efficiency of this dynamic MLC leaf-sequencing method was evaluated using external beam treatment plans delivered by intensity modulated radiation therapy technique. Methods: To qualify and validate this algorithm, integral test for the beam segment of MLC generated by the CORVUS treatment planning system was performed with clinical intensity map experiments. The treatment plans were optimized and the fluence maps for all photon beams were determined. This algorithm started with the algebraic expression for the area under the beammore » profile. The coefficients in the expression can be transformed into the specifications for the leaf-setting sequence. The leaf optimization procedure was then applied and analyzed for clinical relevant intensity profiles in cancer treatment. Results: The macrophysical effect of this method can be described by volumetric plan evaluation tools such as dose-volume histograms (DVHs). The DVH results are in good agreement compared to those from the CORVUS treatment planning system. Conclusion: We developed a dynamic MLC method to examine the stability of leaf speed including effects of acceleration and deceleration of leaf motion in order to make sure the stability of leaf speed did not affect the intensity profile generated. It was found that the mechanical requirements were better satisfied using this method. The Project is sponsored by the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry.« less

Transformation (normalization) of slope gradient and surface curvatures, automated for statistical analyses from DEMs

NASA Astrophysics Data System (ADS)

Csillik, O.; Evans, I. S.; Drăguţ, L.

2015-03-01

Automated procedures are developed to alleviate long tails in frequency distributions of morphometric variables. They minimize the skewness of slope gradient frequency distributions, and modify the kurtosis of profile and plan curvature distributions toward that of the Gaussian (normal) model. Box-Cox (for slope) and arctangent (for curvature) transformations are tested on nine digital elevation models (DEMs) of varying origin and resolution, and different landscapes, and shown to be effective. Resulting histograms are illustrated and show considerable improvements over those for previously recommended slope transformations (sine, square root of sine, and logarithm of tangent). Unlike previous approaches, the proposed method evaluates the frequency distribution of slope gradient values in a given area and applies the most appropriate transform if required. Sensitivity of the arctangent transformation is tested, showing that Gaussian-kurtosis transformations are acceptable also in terms of histogram shape. Cube root transformations of curvatures produced bimodal histograms. The transforms are applicable to morphometric variables and many others with skewed or long-tailed distributions. By avoiding long tails and outliers, they permit parametric statistics such as correlation, regression and principal component analyses to be applied, with greater confidence that requirements for linearity, additivity and even scatter of residuals (constancy of error variance) are likely to be met. It is suggested that such transformations should be routinely applied in all parametric analyses of long-tailed variables. Our Box-Cox and curvature automated transformations are based on a Python script, implemented as an easy-to-use script tool in ArcGIS.

Operating and Maintaining Energy Smart Schools Action Plan Template - All Action Plans

DOE Office of Scientific and Technical Information (OSTI.GOV)

none,

2009-07-01

EnergySmart Schools action plan templates for benchmarking, lighting, HVAC, water heating, building envelope, transformer, plug loads, kitchen equipment, swimming pool, building automation system, other.

Primers-4-Yeast: a comprehensive web tool for planning primers for Saccharomyces cerevisiae.

PubMed

Yofe, Ido; Schuldiner, Maya

2014-02-01

The budding yeast Saccharomyces cerevisiae is a key model organism of functional genomics, due to its ease and speed of genetic manipulations. In fact, in this yeast, the requirement for homologous sequences for recombination purposes is so small that 40 base pairs (bp) are sufficient. Hence, an enormous variety of genetic manipulations can be performed by simply planning primers with the correct homology, using a defined set of transformation plasmids. Although designing primers for yeast transformations and for the verification of their correct insertion is a common task in all yeast laboratories, primer planning is usually done manually and a tool that would enable easy, automated primer planning for the yeast research community is still lacking. Here we introduce Primers-4-Yeast, a web tool that allows primers to be designed in batches for S. cerevisiae gene-targeting transformations, and for the validation of correct insertions. This novel tool enables fast, automated, accurate primer planning for large sets of genes, introduces consistency in primer planning and is therefore suggested to serve as a standard in yeast research. Primers-4-Yeast is available at: http://www.weizmann.ac.il/Primers-4-Yeast Copyright © 2013 John Wiley & Sons, Ltd.

Transformation of topic-specific professional knowledge into personal pedagogical content knowledge through lesson planning

NASA Astrophysics Data System (ADS)

Stender, Anita; Brückmann, Maja; Neumann, Knut

2017-08-01

This study investigates the relationship between two different types of pedagogical content knowledge (PCK): the topic-specific professional knowledge (TSPK) and practical routines, so-called teaching scripts. Based on the Transformation Model of Lesson Planning, we assume that teaching scripts originate from a transformation of TSPK during lesson planning: When planning lessons, teachers use their TSPK to create lesson plans. The implementation of these lesson plans and teachers' reflection upon them lead to their improvement. Gradually, successful lesson plans are mentally stored as teaching scripts and can easily be retrieved during instruction. This process is affected by teacher's beliefs, motivation and self-regulation. In order to examine the influence of TSPK on teaching scripts as well as the moderating effects of beliefs, motivation and self-regulation, we conducted a cross-sectional study with n = 49 in-service teachers in physics. The TSPK, beliefs, motivation, self-regulation and the quality of teaching scripts of in-service teachers were assessed by using an online questionnaire adapted to teaching the force concept and Newton's law for 9th grade instruction. Based on the measurement of the quality of teaching scripts, the results provide evidence that TSPK influences the quality of teaching scripts. Motivation and self-regulation moderate this influence.

Research on Robot Pose Control Technology Based on Kinematics Analysis Model

NASA Astrophysics Data System (ADS)

Liu, Dalong; Xu, Lijuan

2018-01-01

In order to improve the attitude stability of the robot, proposes an attitude control method of robot based on kinematics analysis model, solve the robot walking posture transformation, grasping and controlling the motion planning problem of robot kinematics. In Cartesian space analytical model, using three axis accelerometer, magnetometer and the three axis gyroscope for the combination of attitude measurement, the gyroscope data from Calman filter, using the four element method for robot attitude angle, according to the centroid of the moving parts of the robot corresponding to obtain stability inertia parameters, using random sampling RRT motion planning method, accurate operation to any position control of space robot, to ensure the end effector along a prescribed trajectory the implementation of attitude control. The accurate positioning of the experiment is taken using MT-R robot as the research object, the test robot. The simulation results show that the proposed method has better robustness, and higher positioning accuracy, and it improves the reliability and safety of robot operation.

Strategic planning for organizational effectiveness during dynamic change.

PubMed

Carlson, Susan L; Harris, Melodee; McLeskey, Nanci

2013-01-01

The leadership of a professional association is charged with developing a strategic plan to operationalize the organization's goals, tactics, and progress. Within the context of its values and goals, a strategic plan steers the organization toward its mission. While there are a variety of models and approaches used in strategic planning, the National Gerontological Nursing Association (NGNA) has historically used goal-based methodology. This method is congruent with the organization's leadership preferences, consistent with the mission-driven culture of the organization, and collaborative in its approach. In 2009 the NGNA Board of Directors initiated a plan for the organization's transformation to a more dynamic and member-driven association through a deliberate process. This article addresses the process used to arrive at the 2010–2011 NGNA strategic initiatives, including a discussion of pertinent data revealed in the 2011 needs assessment survey and NGNA's future initiatives focused on networking, communication, and membership benefits. This process is relevant for all organizations and groups seeking improvement in serving their constituents.

A faculty created strategic plan for excellence in nursing education.

PubMed

Evans, Connie Joan; Francis Shackell, Eileen; Jean Kerr-Wilson, Selma; Joan Doyle, Glynda; McCutcheon, Jodie Anita; Budz, Bernice

2014-02-08

Strategic planning for nursing education, when seen through a faculty lens creates a deeper, more meaningful critical analysis of effective program development. New strategies are required for academic institutions to transform their curricula to meet the needs of a dynamic healthcare and changing global environment to provide quality education for students. In this article, an evidence-informed process is presented that was progressively co-created by the faculty and facilitators. Seminal business frameworks, leadership development philosophies, and innovative interventions enabled faculty to become engaged and developed as they created a strategic plan for a future-driven nursing program. Phase One presents the process of developing a strategic plan for excellence in nursing education by leveraging faculty potential and preparing for an upcoming accreditation. In Phase Two, four team members from Phase One continue as part of Phase Two team serving as the collective memory for this initial work. This method of strategic planning encouraged faculty engagement and leadership and laid the groundwork for a positive culture change among nursing faculty.

Optimal sample sizes for the design of reliability studies: power consideration.

PubMed

Shieh, Gwowen

2014-09-01

Intraclass correlation coefficients are used extensively to measure the reliability or degree of resemblance among group members in multilevel research. This study concerns the problem of the necessary sample size to ensure adequate statistical power for hypothesis tests concerning the intraclass correlation coefficient in the one-way random-effects model. In view of the incomplete and problematic numerical results in the literature, the approximate sample size formula constructed from Fisher's transformation is reevaluated and compared with an exact approach across a wide range of model configurations. These comprehensive examinations showed that the Fisher transformation method is appropriate only under limited circumstances, and therefore it is not recommended as a general method in practice. For advance design planning of reliability studies, the exact sample size procedures are fully described and illustrated for various allocation and cost schemes. Corresponding computer programs are also developed to implement the suggested algorithms.

SU-E-T-465: Dose Calculation Method for Dynamic Tumor Tracking Using a Gimbal-Mounted Linac

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sugimoto, S; Inoue, T; Kurokawa, C

Purpose: Dynamic tumor tracking using the gimbal-mounted linac (Vero4DRT, Mitsubishi Heavy Industries, Ltd., Japan) has been available when respiratory motion is significant. The irradiation accuracy of the dynamic tumor tracking has been reported to be excellent. In addition to the irradiation accuracy, a fast and accurate dose calculation algorithm is needed to validate the dose distribution in the presence of respiratory motion because the multiple phases of it have to be considered. A modification of dose calculation algorithm is necessary for the gimbal-mounted linac due to the degrees of freedom of gimbal swing. The dose calculation algorithm for the gimbalmore » motion was implemented using the linear transformation between coordinate systems. Methods: The linear transformation matrices between the coordinate systems with and without gimbal swings were constructed using the combination of translation and rotation matrices. The coordinate system where the radiation source is at the origin and the beam axis along the z axis was adopted. The transformation can be divided into the translation from the radiation source to the gimbal rotation center, the two rotations around the center relating to the gimbal swings, and the translation from the gimbal center to the radiation source. After operating the transformation matrix to the phantom or patient image, the dose calculation can be performed as the no gimbal swing. The algorithm was implemented in the treatment planning system, PlanUNC (University of North Carolina, NC). The convolution/superposition algorithm was used. The dose calculations with and without gimbal swings were performed for the 3 × 3 cm{sup 2} field with the grid size of 5 mm. Results: The calculation time was about 3 minutes per beam. No significant additional time due to the gimbal swing was observed. Conclusions: The dose calculation algorithm for the finite gimbal swing was implemented. The calculation time was moderate.« less

Linking Nurses' Clinical Leadership to Patient Care Quality: The Role of Transformational Leadership and Workplace Empowerment.

PubMed

Boamah, Sheila

2018-03-01

Background While improving patient safety requires strong nursing leadership, there has been little empirical research that has examined the mechanisms by which leadership influences patient safety outcomes. Aim To test a model examining relationships among transformational leadership, structural empowerment, staff nurse clinical leadership, and nurse-assessed adverse patient outcomes. Methods A cross-sectional survey was conducted with a randomly selected sample of 378 registered nurses working in direct patient care in acute care hospitals across Ontario, Canada. Structural equation modeling was used to test the hypothesized model. Results The model had an acceptable fit, and all paths were significant. Transformational leadership was significantly associated with decreased adverse patient outcomes through structural empowerment and staff nurse clinical leadership. Discussion This study highlights the importance of transformational leadership in creating empowering practice environments that foster high-quality care. The findings indicate that a more complete understanding of what drives desired patient outcomes warrants the need to focus on how to empower nurses and foster clinical leadership practices at the point of care. Conclusion In planning safety strategies, managers must demonstrate transformational leadership behaviors in order to modify the work environment to create better defenses for averting adverse events.

Applying Wave (registered trademark) to Build an Air Force Community of Interest Shared Space

DTIC Science & Technology

2007-08-01

Performance. It is essential that an inverse transform be defined for every transform, or else the query mediator must be smart enough to figure out how...to invert it. Without an inverse transform , if an incoming query constrains on the transformed attribute, the query mediator might generate a query...plan that is horribly inefficient. If you must code a custom transformation function, you must also code the inverse transform . Putting the

SU-E-T-99: Design and Development of Isocenter Parameter System for CT Simulation Laser Based On DICOM RT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Luo, G

2014-06-01

Purpose: In order to receive DICOM files from treatment planning system and generate patient isocenter positioning parameter file for CT laser system automatically, this paper presents a method for communication with treatment planning system and calculation of isocenter parameter for each radiation field. Methods: Coordinate transformation and laser positioning file formats were analyzed, isocenter parameter was calculated via data from DICOM CT Data and DICOM RTPLAN file. An in-house software-DicomGenie was developed based on the object-oriented program platform-Qt with DCMTK SDK (Germany OFFIS company DICOM SDK) . DicomGenie was tested for accuracy using Philips CT simulation plan system (Tumor LOC,more » Philips) and A2J CT positioning laser system (Thorigny Sur Marne, France). Results: DicomGenie successfully established DICOM communication between treatment planning system, DICOM files were received by DicomGenie and patient laser isocenter information was generated accurately. Patient laser parameter data files can be used for for CT laser system directly. Conclusion: In-house software DicomGenie received and extracted DICOM data, isocenter laser positioning data files were created by DicomGenie and can be use for A2J laser positioning system.« less

Computers in a Learning Society. Testimony given before the House Science and Technology Subcommittee on Domestic and International Planning, Analysis, and Cooperation (Washington, D.C., October 13, 1977).

ERIC Educational Resources Information Center

Brown, John Seely; Goldstein, Ira

A revolution that will transform learning in our society, altering both the methods and the content of education, has been made possible by harnessing tomorrow's powerful computer technology to serve as intelligent instructional systems. The unique quality of the computer that makes a revolution possible is that it can serve not only as a…

Transforming an EPA QA/R-2 quality management plan into an ISO 9002 quality management system.

PubMed

Kell, R A; Hedin, C M; Kassakhian, G H; Reynolds, E S

2001-01-01

The Environmental Protection Agency's (EPA) Office of Emergency and Remedial Response (OERR) requires environmental data of known quality to support Superfund hazardous waste site projects. The Quality Assurance Technical Support (QATS) Program is operated by Shaw Environmental and Infrastructure, Inc. to provide EPA's Analytical Operations Center (AOC) with performance evaluation samples, reference materials, on-site laboratory auditing capabilities, data audits (including electronic media data audits), methods development, and other support services. The new QATS contract awarded in November 2000 required that the QATS Program become ISO 9000 certified. In a first for an EPA contractor, the QATS staff and management successfully transformed EPA's QA/R-2 type Quality Management Plan into a Quality Management System (QMS) that complies with the requirements of the internationally recognized ISO 9002 standard and achieved certification in the United States, Canada, and throughout Europe. The presentation describes how quality system elements of ISO 9002 were implemented on an already existing quality system. The psychological and organizational challenges of the culture change in QATS' day-to-day operations will be discussed for the benefit of other ISO 9000 aspirants.

The Study of Thermal Comfort in Transforming Residential Area in Bandung using ENVI-met Software. Case Study: Progo Street

NASA Astrophysics Data System (ADS)

Aziz Soelaiman, Tubagus M.; Soedarsono, Woerjantari K.; Donny Koerniawan, M.

2018-05-01

Bandung has a high potential in attracting tourists. This potential impact on building function near tourist attraction that can transform residential uses into commercial uses. Progo Street and its surrounding area used as the case study, which is close to Gedung Sate and Riau Street as tourist destinations in Bandung. Moreover, this transformation is also reinforced by the spatial planning policies in Bandung, known as RTRW and RDTR, said that this area will be fully non-residential area. This condition in some cases could affect thermal comfort. This paper provides the changes of thermal comfort phenomenon that occurs using EnviMet software. The study compares Predicted Mean Voted (PMV) as thermal comfort indicator between existing and Bandung detailed spatial plan (RDTR) condition. The result shows that the PMV value of current condition is higher than future planning, nonetheless the planned area will be changed into higher non-residential buildings and less greeneries. Some environmental factors that are used to calculate PMV such as air temperature, mean radiant temperature, humidity, and wind speed are also examined to find out what makes the plan more comfortable than the existing. Simulations using ENVI-met software could be considered in making more objective planning policy in the future.

Measuring dynamics of household vulnerability in selected coastal megacities to inform transformative adaptation

NASA Astrophysics Data System (ADS)

Birkmann, J.; Solecki, W. D.

2016-12-01

Understanding conditions and dynamics of household vulnerability and risk is key for building community resilience. Two different methodological approaches of vulnerability, risk and resilience assessment for selected global megacities are presented to address this research issue. First, an indicator-based approach was executed to compare susceptibility, coping and adaptive capacities for Lagos, Kolkata, Lagos, London, New York, and Tokyo on a neighborhood by neighborhood scale. Second, a household survey that has been conducted in Kolkata, Lagos, and New York to explore specific features of susceptibility, risk management capacities and transformations within at risk neighborhoods. The results of both methods underscore the dynamics of vulnerability. Lessons learned for disaster risk management and urban planning are derived, particularly in terms of defining priorities for a more inclusive and resilient urban development, and transformative adaptation. The findings also provide opportunity to critically review the potential outcomes of the New Urban Agenda (outcome of UN-Habitat III). The research has been undertaken within a larger international research team in the Belmont funded project Transformation of Urban Coasts.

Effective Strategic Planning for Community Colleges Founded upon Transformational Management Theory

ERIC Educational Resources Information Center

Joseph, Oscar, III

2013-01-01

The transformational management philosophy creates a culture that has purpose, moral standards, and high achievement outcomes (Yukl, 2006). The primary focus of transformational management theory is to be humane, while exhibiting behavioral characteristics of kindness, care, compassion, and principled centeredness (ethical disposition) designed to…

Transformation of an academic medical center: lessons learned from restructuring and downsizing.

PubMed

Woodard, B; Fottler, M D; Kilpatrick, A O

1999-01-01

This article reviews management literature on health care transformation and describes the processes, including restructuring, job redesign, and downsizing, involved in one academic medical center's experience. The article concludes with lessons learned at each of the stages of the transformation process: planning, implementation, and process continuation. Managerial implications for similar transformation efforts in other health care organizations are suggested.

High Energy Power and Propulsion Capability Roadmap: General Background and Introduction

NASA Technical Reports Server (NTRS)

Bankston, Perry

2005-01-01

Agency objective are: Strategic Planning Transformation. Advanced Planning Organizational Roles. Public Involvement in Strategic Planning. Strategic Roadmaps and Schedule Capability Roadmaps and Schedule. Purpose of NRC Review. Capability Roadmap Development (Progress to Date).

Situationally driven local navigation for mobile robots. Ph.D. Thesis

NASA Technical Reports Server (NTRS)

Slack, Marc Glenn

1990-01-01

For mobile robots to autonomously accommodate dynamically changing navigation tasks in a goal-directed fashion, they must employ navigation plans. Any such plan must provide for the robot's immediate and continuous need for guidance while remaining highly flexible in order to avoid costly computation each time the robot's perception of the world changes. Due to the world's uncertainties, creation and maintenance of navigation plans cannot involve arbitrarily complex processes, as the robot's perception of the world will be in constant flux, requiring modifications to be made quickly if they are to be of any use. This work introduces navigation templates (NaT's) which are building blocks for the construction and maintenance of rough navigation plans which capture the relationship that objects in the world have to the current navigation task. By encoding only the critical relationship between the objects in the world and the navigation task, a NaT-based navigation plan is highly flexible; allowing new constraints to be quickly incorporated into the plan and existing constraints to be updated or deleted from the plan. To satisfy the robot's need for immediate local guidance, the NaT's forming the current navigation plan are passed to a transformation function. The transformation function analyzes the plan with respect to the robot's current location to quickly determine (a few times a second) the locally preferred direction of travel. This dissertation presents NaT's and the transformation function as well as the needed support systems to demonstrate the usefulness of the technique for controlling the actions of a mobile robot operating in an uncertain world.

Action Research to Support the Sustainability of Strategic Planning

ERIC Educational Resources Information Center

Antheil, Jane H.; Spinelli, Stephen, Jr.

2011-01-01

This article suggests that developing a strategic plan, even through a highly participative and data-driven process, is not sufficient to sustain change if implementation of the plan is not monitored as an organizational change event. To the degree that a strategic plan is institutionally transformative, monitoring change during implementation…

Introduction to Strategic Planning in Student Affairs: A Model for Process and Elements of a Plan

ERIC Educational Resources Information Center

Ellis, Shannon E.

2010-01-01

Planning from a strategic perspective has been a mainstay of organizational management for decades. Founded in the private sector, strategic planning is now embraced by the nonprofit world as a catalyst for sound resource allocation, transformative decision making, and motivating staff. Student affairs professionals who think, plan, and act…

Design, development and clinical validation of computer-aided surgical simulation system for streamlined orthognathic surgical planning.

PubMed

Yuan, Peng; Mai, Huaming; Li, Jianfu; Ho, Dennis Chun-Yu; Lai, Yingying; Liu, Siting; Kim, Daeseung; Xiong, Zixiang; Alfi, David M; Teichgraeber, John F; Gateno, Jaime; Xia, James J

2017-12-01

There are many proven problems associated with traditional surgical planning methods for orthognathic surgery. To address these problems, we developed a computer-aided surgical simulation (CASS) system, the AnatomicAligner, to plan orthognathic surgery following our streamlined clinical protocol. The system includes six modules: image segmentation and three-dimensional (3D) reconstruction, registration and reorientation of models to neutral head posture, 3D cephalometric analysis, virtual osteotomy, surgical simulation, and surgical splint generation. The accuracy of the system was validated in a stepwise fashion: first to evaluate the accuracy of AnatomicAligner using 30 sets of patient data, then to evaluate the fitting of splints generated by AnatomicAligner using 10 sets of patient data. The industrial gold standard system, Mimics, was used as the reference. When comparing the results of segmentation, virtual osteotomy and transformation achieved with AnatomicAligner to the ones achieved with Mimics, the absolute deviation between the two systems was clinically insignificant. The average surface deviation between the two models after 3D model reconstruction in AnatomicAligner and Mimics was 0.3 mm with a standard deviation (SD) of 0.03 mm. All the average surface deviations between the two models after virtual osteotomy and transformations were smaller than 0.01 mm with a SD of 0.01 mm. In addition, the fitting of splints generated by AnatomicAligner was at least as good as the ones generated by Mimics. We successfully developed a CASS system, the AnatomicAligner, for planning orthognathic surgery following the streamlined planning protocol. The system has been proven accurate. AnatomicAligner will soon be available freely to the boarder clinical and research communities.

Transforming the Department of State: Adapting Operational Capacities and Capabilities to the Post-9/11 Reality, Evolving Interagency Responsibilities, and the Challenges of the 21st Century

DTIC Science & Technology

2006-04-14

combination of the Strategic Plan, MPPs, and BPPs goals, along with performance, and accountability plans. Three other documents are inherently important...DOS Strategic Plan, Mission Performance Plan (MPP), Bureau Performance Plan ( BPP ). NSC representation, POLADs, Embassy Country Teams, and...the world. DOS Strategic Plan, Mission Performance Plan (MPP), Bureau Performance Plan ( BPP ). NSC representation, POLADs, Exchange

Transforming user needs into functional requirements for an antibiotic clinical decision support system: explicating content analysis for system design.

PubMed

Bright, T J

2013-01-01

Many informatics studies use content analysis to generate functional requirements for system development. Explication of this translational process from qualitative data to functional requirements can strengthen the understanding and scientific rigor when applying content analysis in informatics studies. To describe a user-centered approach transforming emergent themes derived from focus group data into functional requirements for informatics solutions and to illustrate these methods to the development of an antibiotic clinical decision support system (CDS). THE APPROACH CONSISTED OF FIVE STEPS: 1) identify unmet therapeutic planning information needs via Focus Group Study-I, 2) develop a coding framework of therapeutic planning themes to refine the domain scope to antibiotic therapeutic planning, 3) identify functional requirements of an antibiotic CDS system via Focus Group Study-II, 4) discover informatics solutions and functional requirements from coded data, and 5) determine the types of information needed to support the antibiotic CDS system and link with the identified informatics solutions and functional requirements. The coding framework for Focus Group Study-I revealed unmet therapeutic planning needs. Twelve subthemes emerged and were clustered into four themes; analysis indicated a need for an antibiotic CDS intervention. Focus Group Study-II included five types of information needs. Comments from the Barrier/Challenge to information access and Function/Feature themes produced three informatics solutions and 13 functional requirements of an antibiotic CDS system. Comments from the Patient, Institution, and Domain themes generated required data elements for each informatics solution. This study presents one example explicating content analysis of focus group data and the analysis process to functional requirements from narrative data. Illustration of this 5-step method was used to develop an antibiotic CDS system, resolving unmet antibiotic prescribing needs. As a reusable approach, these techniques can be refined and applied to resolve unmet information needs with informatics interventions in additional domains.

Advanced Telescopes and Observatories and Scientific Instruments and Sensors Capability Roadmaps: General Background and Introduction

NASA Technical Reports Server (NTRS)

Coulter, Dan; Bankston, Perry

2005-01-01

Agency objective are: Strategic Planning Transformation. Advanced Planning Organizational Roles. Public Involvement in Strategic Planning. Strategic Roadmaps and Schedule. Capability Roadmaps and Schedule. Purpose of NRC Review. Capability Roadmap Development (Progress to Date).

The Need for a General Comment for Article 19 of the UN Convention on the Rights of the Child: Toward Enlightenment and Progress for Child Protection

ERIC Educational Resources Information Center

Bennett, Susan; Hart, Stuart N.; Svevo-Cianci, Kimberly Ann

2009-01-01

Objective: To present the need and plan for development of a General Comment for the UN Convention on the Rights of the Child Article 19 which has the potential to transform and advance child protection through the infusion of a child rights approach. Methods: The Committee on the Rights of the Child (Committee) authorized ISPCAN and IICRD to…

A method for acquiring random range uncertainty probability distributions in proton therapy

NASA Astrophysics Data System (ADS)

Holloway, S. M.; Holloway, M. D.; Thomas, S. J.

2018-01-01

In treatment planning we depend upon accurate knowledge of geometric and range uncertainties. If the uncertainty model is inaccurate then the plan will produce under-dosing of the target and/or overdosing of OAR. We aim to provide a method for which centre and site-specific population range uncertainty due to inter-fraction motion can be quantified to improve the uncertainty model in proton treatment planning. Daily volumetric MVCT data from previously treated radiotherapy patients has been used to investigate inter-fraction changes to water equivalent path-length (WEPL). Daily image-guidance scans were carried out for each patient and corrected for changes in CTV position (using rigid transformations). An effective depth algorithm was used to determine residual range changes, after corrections had been applied, throughout the treatment by comparing WEPL within the CTV at each fraction for several beam angles. As a proof of principle this method was used to quantify uncertainties for inter-fraction range changes for a sample of head and neck patients of Σ=3.39 mm, σ = 4.72 mm and overall mean = -1.82 mm. For prostate Σ=5.64 mm, σ = 5.91 mm and overall mean = 0.98 mm. The choice of beam angle for head and neck did not affect the inter-fraction range error significantly; however this was not the same for prostate. Greater range changes were seen using a lateral beam compared to an anterior beam for prostate due to relative motion of the prostate and femoral heads. A method has been developed to quantify population range changes due to inter-fraction motion that can be adapted for the clinic. The results of this work highlight the importance of robust planning and analysis in proton therapy. Such information could be used in robust optimisation algorithms or treatment plan robustness analysis. Such knowledge will aid in establishing beam start conditions at planning and for establishing adaptive planning protocols.

Image Fusion of CT and MR with Sparse Representation in NSST Domain

PubMed Central

Qiu, Chenhui; Wang, Yuanyuan; Zhang, Huan

2017-01-01

Multimodal image fusion techniques can integrate the information from different medical images to get an informative image that is more suitable for joint diagnosis, preoperative planning, intraoperative guidance, and interventional treatment. Fusing images of CT and different MR modalities are studied in this paper. Firstly, the CT and MR images are both transformed to nonsubsampled shearlet transform (NSST) domain. So the low-frequency components and high-frequency components are obtained. Then the high-frequency components are merged using the absolute-maximum rule, while the low-frequency components are merged by a sparse representation- (SR-) based approach. And the dynamic group sparsity recovery (DGSR) algorithm is proposed to improve the performance of the SR-based approach. Finally, the fused image is obtained by performing the inverse NSST on the merged components. The proposed fusion method is tested on a number of clinical CT and MR images and compared with several popular image fusion methods. The experimental results demonstrate that the proposed fusion method can provide better fusion results in terms of subjective quality and objective evaluation. PMID:29250134

Study on Noise Prediction Model and Control Schemes for Substation

PubMed Central

Gao, Yang; Liu, Songtao

2014-01-01

With the government's emphasis on environmental issues of power transmission and transformation project, noise pollution has become a prominent problem now. The noise from the working transformer, reactor, and other electrical equipment in the substation will bring negative effect to the ambient environment. This paper focuses on using acoustic software for the simulation and calculation method to control substation noise. According to the characteristics of the substation noise and the techniques of noise reduction, a substation's acoustic field model was established with the SoundPLAN software to predict the scope of substation noise. On this basis, 4 reasonable noise control schemes were advanced to provide some helpful references for noise control during the new substation's design and construction process. And the feasibility and application effect of these control schemes can be verified by using the method of simulation modeling. The simulation results show that the substation always has the problem of excessive noise at boundary under the conventional measures. The excess noise can be efficiently reduced by taking the corresponding noise reduction methods. PMID:24672356

Wavelets in medical imaging

NASA Astrophysics Data System (ADS)

Zahra, Noor e.; Sevindir, Hulya Kodal; Aslan, Zafer; Siddiqi, A. H.

2012-07-01

The aim of this study is to provide emerging applications of wavelet methods to medical signals and images, such as electrocardiogram, electroencephalogram, functional magnetic resonance imaging, computer tomography, X-ray and mammography. Interpretation of these signals and images are quite important. Nowadays wavelet methods have a significant impact on the science of medical imaging and the diagnosis of disease and screening protocols. Based on our initial investigations, future directions include neurosurgical planning and improved assessment of risk for individual patients, improved assessment and strategies for the treatment of chronic pain, improved seizure localization, and improved understanding of the physiology of neurological disorders. We look ahead to these and other emerging applications as the benefits of this technology become incorporated into current and future patient care. In this chapter by applying Fourier transform and wavelet transform, analysis and denoising of one of the important biomedical signals like EEG is carried out. The presence of rhythm, template matching, and correlation is discussed by various method. Energy of EEG signal is used to detect seizure in an epileptic patient. We have also performed denoising of EEG signals by SWT.

Image Fusion of CT and MR with Sparse Representation in NSST Domain.

PubMed

Qiu, Chenhui; Wang, Yuanyuan; Zhang, Huan; Xia, Shunren

2017-01-01

Multimodal image fusion techniques can integrate the information from different medical images to get an informative image that is more suitable for joint diagnosis, preoperative planning, intraoperative guidance, and interventional treatment. Fusing images of CT and different MR modalities are studied in this paper. Firstly, the CT and MR images are both transformed to nonsubsampled shearlet transform (NSST) domain. So the low-frequency components and high-frequency components are obtained. Then the high-frequency components are merged using the absolute-maximum rule, while the low-frequency components are merged by a sparse representation- (SR-) based approach. And the dynamic group sparsity recovery (DGSR) algorithm is proposed to improve the performance of the SR-based approach. Finally, the fused image is obtained by performing the inverse NSST on the merged components. The proposed fusion method is tested on a number of clinical CT and MR images and compared with several popular image fusion methods. The experimental results demonstrate that the proposed fusion method can provide better fusion results in terms of subjective quality and objective evaluation.

Registration of clinical volumes to beams-eye-view images for real-time tracking

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bryant, Jonathan H.; Rottmann, Joerg; Lewis, John H.

2014-12-15

Purpose: The authors combine the registration of 2D beam’s eye view (BEV) images and 3D planning computed tomography (CT) images, with relative, markerless tumor tracking to provide automatic absolute tracking of physician defined volumes such as the gross tumor volume (GTV). Methods: During treatment of lung SBRT cases, BEV images were continuously acquired with an electronic portal imaging device (EPID) operating in cine mode. For absolute registration of physician-defined volumes, an intensity based 2D/3D registration to the planning CT was performed using the end-of-exhale (EoE) phase of the four dimensional computed tomography (4DCT). The volume was converted from Hounsfield unitsmore » into electron density by a calibration curve and digitally reconstructed radiographs (DRRs) were generated for each beam geometry. Using normalized cross correlation between the DRR and an EoE BEV image, the best in-plane rigid transformation was found. The transformation was applied to physician-defined contours in the planning CT, mapping them into the EPID image domain. A robust multiregion method of relative markerless lung tumor tracking quantified deviations from the EoE position. Results: The success of 2D/3D registration was demonstrated at the EoE breathing phase. By registering at this phase and then employing a separate technique for relative tracking, the authors are able to successfully track target volumes in the BEV images throughout the entire treatment delivery. Conclusions: Through the combination of EPID/4DCT registration and relative tracking, a necessary step toward the clinical implementation of BEV tracking has been completed. The knowledge of tumor volumes relative to the treatment field is important for future applications like real-time motion management, adaptive radiotherapy, and delivered dose calculations.« less

CCBC Academic and Campus Plans, 2002-2004.

ERIC Educational Resources Information Center

Baltimore County Community Coll., MD.

This Community College of Baltimore County (CCBC) (Maryland) academic plan provides direction to the college in its transformation into a learning college of the 21st century. The College's strategic plan, LearningFirst, provides the foundation and the inspiration for the academic plan, which advances two central themes contained in CCBC's vision:…

Transformational Assessment: A Simplified Model of Strategic Planning

ERIC Educational Resources Information Center

Bardwell, Rebecca

2008-01-01

Strategic planning is a way to evaluate a present situation and set a course for the future. While there is no dearth of literature on Strategic Planning, there appears to be reluctance on the part of K-12 educators to engage in strategic planning. Besides the cynicism about change, another roadblock to strategic planning is the time it takes.…

Training for planning tumour resection: augmented reality and human factors.

PubMed

Abhari, Kamyar; Baxter, John S H; Chen, Elvis C S; Khan, Ali R; Peters, Terry M; de Ribaupierre, Sandrine; Eagleson, Roy

2015-06-01

Planning surgical interventions is a complex task, demanding a high degree of perceptual, cognitive, and sensorimotor skills to reduce intra- and post-operative complications. This process requires spatial reasoning to coordinate between the preoperatively acquired medical images and patient reference frames. In the case of neurosurgical interventions, traditional approaches to planning tend to focus on providing a means for visualizing medical images, but rarely support transformation between different spatial reference frames. Thus, surgeons often rely on their previous experience and intuition as their sole guide is to perform mental transformation. In case of junior residents, this may lead to longer operation times or increased chance of error under additional cognitive demands. In this paper, we introduce a mixed augmented-/virtual-reality system to facilitate training for planning a common neurosurgical procedure, brain tumour resection. The proposed system is designed and evaluated with human factors explicitly in mind, alleviating the difficulty of mental transformation. Our results indicate that, compared to conventional planning environments, the proposed system greatly improves the nonclinicians' performance, independent of the sensorimotor tasks performed ( ). Furthermore, the use of the proposed system by clinicians resulted in a significant reduction in time to perform clinically relevant tasks ( ). These results demonstrate the role of mixed-reality systems in assisting residents to develop necessary spatial reasoning skills needed for planning brain tumour resection, improving patient outcomes.

Sequential quadratic programming-based fast path planning algorithm subject to no-fly zone constraints

NASA Astrophysics Data System (ADS)

Liu, Wei; Ma, Shunjian; Sun, Mingwei; Yi, Haidong; Wang, Zenghui; Chen, Zengqiang

2016-08-01

Path planning plays an important role in aircraft guided systems. Multiple no-fly zones in the flight area make path planning a constrained nonlinear optimization problem. It is necessary to obtain a feasible optimal solution in real time. In this article, the flight path is specified to be composed of alternate line segments and circular arcs, in order to reformulate the problem into a static optimization one in terms of the waypoints. For the commonly used circular and polygonal no-fly zones, geometric conditions are established to determine whether or not the path intersects with them, and these can be readily programmed. Then, the original problem is transformed into a form that can be solved by the sequential quadratic programming method. The solution can be obtained quickly using the Sparse Nonlinear OPTimizer (SNOPT) package. Mathematical simulations are used to verify the effectiveness and rapidity of the proposed algorithm.

NASA's Human Planetary Landing Systems Capability Roadmap Development: General Background and Introduction

NASA Technical Reports Server (NTRS)

Mueller, Rob

2005-01-01

General Background and Introduction of Capability Roadmaps Agency Objective. Strategic Planning Transformation. Advanced Planning Organizational Roles. Public Involvement in Strategic Planning. Strategic Roadmaps and Schedule. Capability Roadmaps and Schedule. Purpose of NRC Review. Capability Roadmap Development (Progress to Date)

Enhancing clinical evidence by proactively building quality into clinical trials.

PubMed

Meeker-O'Connell, Ann; Glessner, Coleen; Behm, Mark; Mulinde, Jean; Roach, Nancy; Sweeney, Fergus; Tenaerts, Pamela; Landray, Martin J

2016-08-01

Stakeholders across the clinical trial enterprise have expressed concern that the current clinical trial enterprise is unsustainable. The cost and complexity of trials have continued to increase, threatening our ability to generate reliable evidence essential for making appropriate decisions concerning the benefits and harms associated with clinical interventions. Overcoming this inefficiency rests on improving protocol design, trial planning, and quality oversight. The Clinical Trials Transformation Initiative convened a project to evaluate methods to prospectively build quality into the scientific and operational design of clinical trials ("quality-by-design"), such that trials are feasible to conduct and important errors are prevented rather than remediated. A working group evaluated aspects of trial design and oversight and developed the Clinical Trials Transformation Initiative quality-by-design principles document, outlining a series of factors generally relevant to the reliability of trial conclusions and to patient safety. These principles were then applied and further refined during a series of hands-on workshops to evaluate their utility in facilitating proactive, cross-functional dialogue, and decision-making about trial design and planning. Following these workshops, independent qualitative interviews were conducted with 19 workshop attendees to explore the potential challenges for implementing a quality-by-design approach to clinical trials. The Clinical Trials Transformation Initiative project team subsequently developed recommendations and an online resource guide to support implementation of this approach. The Clinical Trials Transformation Initiative quality-by-design principles provide a framework for assuring that clinical trials adequately safeguard participants and provide reliable information on which to make decisions on the effects of treatments. The quality-by-design workshops highlighted the value of active discussions incorporating the different perspectives within and external to an organization (e.g. clinical investigators, research site staff, and trial participants) in improving trial design. Workshop participants also recognized the value of focusing oversight on those aspects of the trial where errors would have a major impact on participant safety and reliability of results. Applying the Clinical Trials Transformation Initiative quality-by-design recommendations and principles should enable organizations to prioritize the most critical determinants of a trial's quality, identify non-essential activities that can be eliminated to streamline trial conduct and oversight, and formulate appropriate plans to define, avoid, mitigate, monitor, and address important errors. © The Author(s) 2016.

Computational Calculation Of The Ionization Energies Of The Human Prion Protein By The Coarse-grain Method

NASA Astrophysics Data System (ADS)

Lyu, Justin; Andrianarijaona, V. M.

2016-05-01

The causes of the misfolding of prion protein -i.e. the transformation of PrPC to PrPSc - have not been clearly elucidated. Many studies have focused on identifying possible chemical conditions, such as pH, temperature and chemical denaturation, that may trigger the pathological transformation of prion proteins (Weiwei Tao, Gwonchan Yoon, Penghui Cao, `` β-sheet-like formation during the mechanical unfolding of prion protein'', The Journal of Chemical Physics, 2015, 143, 125101). Here, we attempt to calculate the ionization energies of the prion protein, which will be able to shed light onto the possible causes of the misfolding. We plan on using the coarse-grain method which allows for a more feasible calculation time by means of approximation. We believe that by being able to approximate the ionization potential, particularly that of the regions known to form stable β-strands of the PrPSc form, the possible sources of denaturation, be it chemical or mechanical, may be narrowed down.

Birkhoffian symplectic algorithms derived from Hamiltonian symplectic algorithms

NASA Astrophysics Data System (ADS)

Xin-Lei, Kong; Hui-Bin, Wu; Feng-Xiang, Mei

2016-01-01

In this paper, we focus on the construction of structure preserving algorithms for Birkhoffian systems, based on existing symplectic schemes for the Hamiltonian equations. The key of the method is to seek an invertible transformation which drives the Birkhoffian equations reduce to the Hamiltonian equations. When there exists such a transformation, applying the corresponding inverse map to symplectic discretization of the Hamiltonian equations, then resulting difference schemes are verified to be Birkhoffian symplectic for the original Birkhoffian equations. To illustrate the operation process of the method, we construct several desirable algorithms for the linear damped oscillator and the single pendulum with linear dissipation respectively. All of them exhibit excellent numerical behavior, especially in preserving conserved quantities. Project supported by the National Natural Science Foundation of China (Grant No. 11272050), the Excellent Young Teachers Program of North China University of Technology (Grant No. XN132), and the Construction Plan for Innovative Research Team of North China University of Technology (Grant No. XN129).

National Strategies of Ophthalmic Education in Iran

PubMed Central

Entezari, A; Javadi, MA; Einollahi, B

2012-01-01

Background: Academic medicine is in a state of dramatic transformation. For this reason strategic thinking is the most essential part of educational planning. The main purpose of the present study was developing the strategic educational planning of Ophthalmology in Iran from 2007 to 2010 Methods: A qualitative investigation using focus group discussion has been implemented successfully for developing educational planning. Six to twelve representatives of key stakeholders in the ophthalmic education of Iran participated to this study. Results: Strengths, weaknesses, opportunities and threats of ophthalmology education in Iran were analyzed. Strategic goals in education, research, and health service providing domains were being developed. Educational goals were defined as training of human resources in accordance with the community needs at the level of general practitioner, specialist, and fellowships in ophthalmology. Research goals of the program were defined as scientific inter-departmental and international communications, in order to promote the level of education, research, and treatment in the country. Also, in the field of health services according to the community needs, providing services by the means of advanced and cost effective methods were defined as strategic objectives. Conclusion: Based on this strategic plan in the last three years ophthalmic education in Iran shall be many changes in educational, research and health care provision for social accountability. PMID:23113125

Behavioral and Social Sciences at the National Institutes of Health: adoption of research findings in health research and practice as a scientific priority.

PubMed

Riley, William T

2017-06-01

The National Institutes of Health's Office of Behavioral and Social Sciences Research (OBSSR) recently released its Strategic Plan for 2017 to 2021. This plan highlights three scientific priorities: (1) improve the synergy of basic and applied behavioral and social sciences research, (2) enhance and promote the research infrastructure, methods, and measures needed to support a more cumulative and integrated approach to behavioral and social sciences research, and (3) facilitate the adoption of behavioral and social sciences research findings in health research and in practice. This commentary focuses on the challenges and opportunities to facilitate the adoption of research findings in health research and in practice. In addition to the ongoing NIH support for dissemination and implementation (D&I) research, we must address transformative challenges and opportunities such as better disseminating and implementing D&I research, merging research and practice, adopting more rigorous and diverse methods and measures for both D&I and clinical trials research, evaluating technological-based delivery of interventions, and transitioning from minimally adaptable intervention packages to planned adaptations rooted in behavior change principles. Beyond translation into practice and policy, the OBSSR Strategic Plan also highlights the need for translation of behavioral and social science findings into the broader biomedical research enterprise.

Humboldt Goes to the Labour Market: How Academic Higher Education Fuels Labour Market Success in the Czech Republic

ERIC Educational Resources Information Center

Pabian, Petr; Sima, Karel; Kyncilova, Lucie

2011-01-01

The Czech Republic is one of the post-communist countries where the transformation from late industrial to knowledge economies and knowledge societies was complicated by the simultaneous transformations from communist centrally planned economies to democratic regimes and market economies. Furthermore, the transformation of higher education itself…

SU-E-T-04: 3D Dose Based Patient Compensator QA Procedure for Proton Radiotherapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zou, W; Reyhan, M; Zhang, M

2015-06-15

Purpose: In proton double-scattering radiotherapy, compensators are the essential patient specific devices to contour the distal dose distribution to the tumor target. Traditional compensator QA is limited to checking the drilled surface profiles against the plan. In our work, a compensator QA process was established that assess the entire compensator including its internal structure for patient 3D dose verification. Methods: The fabricated patient compensators were CT scanned. Through mathematical image processing and geometric transformations, the CT images of the proton compensator were combined with the patient simulation CT images into a new series of CT images, in which the imagedmore » compensator is placed at the planned location along the corresponding beam line. The new CT images were input into the Eclipse treatment planning system. The original plan was calculated to the combined CT image series without the plan compensator. The newly computed patient 3D dose from the combined patientcompensator images was verified against the original plan dose. Test plans include the compensators with defects intentionally created inside the fabricated compensators. Results: The calculated 3D dose with the combined compensator and patient CT images reflects the impact of the fabricated compensator to the patient. For the test cases in which no defects were created, the dose distributions were in agreement between our method and the corresponding original plans. For the compensator with the defects, the purposely changed material and a purposely created internal defect were successfully detected while not possible with just the traditional compensator profiles detection methods. Conclusion: We present here a 3D dose verification process to qualify the fabricated proton double-scattering compensator. Such compensator detection process assesses the patient 3D impact of the fabricated compensator surface profile as well as the compensator internal material and structure changes. This research receives funding support from CURA Medical Technologies.« less

A 3D global-to-local deformable mesh model based registration and anatomy-constrained segmentation method for image guided prostate radiotherapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou Jinghao; Kim, Sung; Jabbour, Salma

2010-03-15

Purpose: In the external beam radiation treatment of prostate cancers, successful implementation of adaptive radiotherapy and conformal radiation dose delivery is highly dependent on precise and expeditious segmentation and registration of the prostate volume between the simulation and the treatment images. The purpose of this study is to develop a novel, fast, and accurate segmentation and registration method to increase the computational efficiency to meet the restricted clinical treatment time requirement in image guided radiotherapy. Methods: The method developed in this study used soft tissues to capture the transformation between the 3D planning CT (pCT) images and 3D cone-beam CTmore » (CBCT) treatment images. The method incorporated a global-to-local deformable mesh model based registration framework as well as an automatic anatomy-constrained robust active shape model (ACRASM) based segmentation algorithm in the 3D CBCT images. The global registration was based on the mutual information method, and the local registration was to minimize the Euclidian distance of the corresponding nodal points from the global transformation of deformable mesh models, which implicitly used the information of the segmented target volume. The method was applied on six data sets of prostate cancer patients. Target volumes delineated by the same radiation oncologist on the pCT and CBCT were chosen as the benchmarks and were compared to the segmented and registered results. The distance-based and the volume-based estimators were used to quantitatively evaluate the results of segmentation and registration. Results: The ACRASM segmentation algorithm was compared to the original active shape model (ASM) algorithm by evaluating the values of the distance-based estimators. With respect to the corresponding benchmarks, the mean distance ranged from -0.85 to 0.84 mm for ACRASM and from -1.44 to 1.17 mm for ASM. The mean absolute distance ranged from 1.77 to 3.07 mm for ACRASM and from 2.45 to 6.54 mm for ASM. The volume overlap ratio ranged from 79% to 91% for ACRASM and from 44% to 80% for ASM. These data demonstrated that the segmentation results of ACRASM were in better agreement with the corresponding benchmarks than those of ASM. The developed registration algorithm was quantitatively evaluated by comparing the registered target volumes from the pCT to the benchmarks on the CBCT. The mean distance and the root mean square error ranged from 0.38 to 2.2 mm and from 0.45 to 2.36 mm, respectively, between the CBCT images and the registered pCT. The mean overlap ratio of the prostate volumes ranged from 85.2% to 95% after registration. The average time of the ACRASM-based segmentation was under 1 min. The average time of the global transformation was from 2 to 4 min on two 3D volumes and the average time of the local transformation was from 20 to 34 s on two deformable superquadrics mesh models. Conclusions: A novel and fast segmentation and deformable registration method was developed to capture the transformation between the planning and treatment images for external beam radiotherapy of prostate cancers. This method increases the computational efficiency and may provide foundation to achieve real time adaptive radiotherapy.« less

75 FR 18551 - Advisory Committee for Polar Programs; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-12

... Visitors meetings; transformative research; and strategic planning. Dated: April 7, 2010. Susanne Bolton... OPP on issues related to long-range planning. Agenda: Staff presentations and discussion on...

Completing the One EPA Web Transformation (Email Message)

EPA Pesticide Factsheets

Deputy administrator Stan Meiburg urged other administrators to review their web transformation progress, and make sure they have requested extensions and planned to temporarily transfer content to the www3 server, before the September 30, 2015 deadline.

Transformational System Concepts and Technologies for Our Future in Space

NASA Technical Reports Server (NTRS)

Howell, Joe T.; Mankins, John C.

2004-01-01

Continued constrained budgets and growing national and international interests in the commercialization and development of space requires NASA to be constantly vigilant, to be creative, and to seize every opportunity for assuring the maximum return on space infrastructure investments. Accordingly, efforts are underway to forge new and innovative approaches to transform our space systems in the future to ultimately achieve two or three or five times as much with the same resources. This bold undertaking can be achieved only through extensive cooperative efforts throughout the aerospace community and truly effective planning to pursue advanced space system design concepts and high-risk/high-leverage research and technology. Definitive implementation strategies and roadmaps containing new methodologies and revolutionary approaches must be developed to economically accommodate the continued exploration and development of space. Transformation can be realized through modular design and stepping stone development. This approach involves sustainable budget levels and multi-purpose systems development of supporting capabilities that lead to a diverse amy of sustainable future space activities. Transformational design and development requires revolutionary advances by using modular designs and a planned, stepping stone development process. A modular approach to space systems potentially offers many improvements over traditional one-of-a-kind space systems comprised of different subsystem element with little standardization in interfaces or functionality. Modular systems must be more flexible, scaleable, reconfigurable, and evolvable. Costs can be reduced through learning curve effects and economies of scale, and by enabling servicing and repair that would not otherwise be feasible. This paper briefly discusses achieving a promising approach to transforming space systems planning and evolution into a meaningful stepping stone design, development, and implementation process. The success of this well planned and orchestrated approach holds great promise for achieving innovation and revolutionary technology development for supporting future exploration and development of space.

The complexity of organizational change: describing communication during organizational turbulence.

PubMed

Salem, Philip

2013-01-01

Organizational researchers and practitioners have been interested in organizational change for some time. Historically, they have directed most of their efforts at improving the efficiency of planned top-down change. These efforts were strategic attempts at altering parameters leading to transformational change. Most efforts failed to meet their intended purposes. Transformational organizational change has not been likely. The legitimate systems have been robust. There has been little systematic investigation of the communication occurring during these efforts. The purpose of this essay is to describe results of a mixed methods research project answering two research questions. (a) How do organizational members communicate during a time of turbulence? (b) What features of this communication suggest the potential for or resistance to transformative change? Comparing the results at the beginning of the period to other periods, gives insight into how social actors communicate and enact the organization during a threshold period where transformational change was possible. Results reveal identifiable patterns of communication as communication strategies, parameters, or basins of attraction. The overall pattern explains how micro communication patterns intersect and how the accumulation of these patterns may resist or accomplish change at a macro level.

Psychiatrist Health Human Resource Planning - An Essential Component of a Hospital-Based Mental Healthcare System Transformation.

PubMed

Jarmain, Sarah

2016-01-01

The World Health Organization (WHO) defines health human resource planning as "the process of estimating the number of persons and the kinds of knowledge, skills, and attitudes they need to achieve predetermined health targets and ultimately health status objectives" (OHA 2015). Health human resource planning is a critical component of successful organizational and system transformation, and yet little has been written on how to do this for physicians at the local level. This paper will outline a framework for developing and managing key aspects of physician human resource planning related to both the quantity and quality of work within a hospital setting. Using the example of a complex multiphase hospital-based mental health transformation that involved both the reduction and divestment of beds and services, we will outline how we managed the physician human resource aspects to establish the number of psychiatrists needed and the desired attributes of those psychiatrists, and how we helped an existing workforce transition to meet the new expectations. The paper will describe a process for strategically aligning the selection and management of physicians to meet organizational vision and mandate.

Beyond Traditional Outcome-Based Education.

ERIC Educational Resources Information Center

Spady, William G.; Marshall, Kit J.

1991-01-01

Transitional outcome-based education lies in the twilight zone between traditional subject matter curriculum structures and planning processes and the future-role priorities inherent in transformational OBE. Districts go through incorporation, integration, and redefinition stages in implementing transitional OBE. Transformational OBE's guiding…

Automated segmentation of the atrial region and fossa ovalis towards computer-aided planning of inter-atrial wall interventions.

PubMed

Morais, Pedro; Vilaça, João L; Queirós, Sandro; Marchi, Alberto; Bourier, Felix; Deisenhofer, Isabel; D'hooge, Jan; Tavares, João Manuel R S

2018-07-01

Image-fusion strategies have been applied to improve inter-atrial septal (IAS) wall minimally-invasive interventions. Hereto, several landmarks are initially identified on richly-detailed datasets throughout the planning stage and then combined with intra-operative images, enhancing the relevant structures and easing the procedure. Nevertheless, such planning is still performed manually, which is time-consuming and not necessarily reproducible, hampering its regular application. In this article, we present a novel automatic strategy to segment the atrial region (left/right atrium and aortic tract) and the fossa ovalis (FO). The method starts by initializing multiple 3D contours based on an atlas-based approach with global transforms only and refining them to the desired anatomy using a competitive segmentation strategy. The obtained contours are then applied to estimate the FO by evaluating both IAS wall thickness and the expected FO spatial location. The proposed method was evaluated in 41 computed tomography datasets, by comparing the atrial region segmentation and FO estimation results against manually delineated contours. The automatic segmentation method presented a performance similar to the state-of-the-art techniques and a high feasibility, failing only in the segmentation of one aortic tract and of one right atrium. The FO estimation method presented an acceptable result in all the patients with a performance comparable to the inter-observer variability. Moreover, it was faster and fully user-interaction free. Hence, the proposed method proved to be feasible to automatically segment the anatomical models for the planning of IAS wall interventions, making it exceptionally attractive for use in the clinical practice. Copyright © 2018 Elsevier B.V. All rights reserved.

Defense Business Transformation: DOD Should Improve Its Planning with and Performance Monitoring of the Military Departments

DTIC Science & Technology

2016-12-01

Departments Report to Congressional Addressees December 2016 GAO-17-9 United States Government Accountability Office United States...Government Accountability Office Highlights of GAO-17-9, a report to congressional addresses December 2016 DEFENSE BUSINESS TRANSFORMATION DOD Should...specific management responsibility, accountability , and control over business transformation efforts and applicable resources across its business

Hesitant Fuzzy Linguistic Preference Utility Set and Its Application in Selection of Fire Rescue Plans

PubMed Central

Si, Guangsen; Xu, Zeshui

2018-01-01

Hesitant fuzzy linguistic term set provides an effective tool to represent uncertain decision information. However, the semantics corresponding to the linguistic terms in it cannot accurately reflect the decision-makers’ subjective cognition. In general, different decision-makers’ sensitivities towards the semantics are different. Such sensitivities can be represented by the cumulative prospect theory value function. Inspired by this, we propose a linguistic scale function to transform the semantics corresponding to linguistic terms into the linguistic preference values. Furthermore, we propose the hesitant fuzzy linguistic preference utility set, based on which, the decision-makers can flexibly express their distinct semantics and obtain the decision results that are consistent with their cognition. For calculations and comparisons over the hesitant fuzzy linguistic preference utility sets, we introduce some distance measures and comparison laws. Afterwards, to apply the hesitant fuzzy linguistic preference utility sets in emergency management, we develop a method to obtain objective weights of attributes and then propose a hesitant fuzzy linguistic preference utility-TOPSIS method to select the best fire rescue plan. Finally, the validity of the proposed method is verified by some comparisons of the method with other two representative methods including the hesitant fuzzy linguistic-TOPSIS method and the hesitant fuzzy linguistic-VIKOR method. PMID:29614019

Hesitant Fuzzy Linguistic Preference Utility Set and Its Application in Selection of Fire Rescue Plans.

PubMed

Liao, Huchang; Si, Guangsen; Xu, Zeshui; Fujita, Hamido

2018-04-03

Hesitant fuzzy linguistic term set provides an effective tool to represent uncertain decision information. However, the semantics corresponding to the linguistic terms in it cannot accurately reflect the decision-makers' subjective cognition. In general, different decision-makers' sensitivities towards the semantics are different. Such sensitivities can be represented by the cumulative prospect theory value function. Inspired by this, we propose a linguistic scale function to transform the semantics corresponding to linguistic terms into the linguistic preference values. Furthermore, we propose the hesitant fuzzy linguistic preference utility set, based on which, the decision-makers can flexibly express their distinct semantics and obtain the decision results that are consistent with their cognition. For calculations and comparisons over the hesitant fuzzy linguistic preference utility sets, we introduce some distance measures and comparison laws. Afterwards, to apply the hesitant fuzzy linguistic preference utility sets in emergency management, we develop a method to obtain objective weights of attributes and then propose a hesitant fuzzy linguistic preference utility-TOPSIS method to select the best fire rescue plan. Finally, the validity of the proposed method is verified by some comparisons of the method with other two representative methods including the hesitant fuzzy linguistic-TOPSIS method and the hesitant fuzzy linguistic-VIKOR method.

Preparing the Army for Stability Operations: Doctrinal and Interagency Issues

DTIC Science & Technology

2007-01-01

discuss these issues at length in Chapter Three). Similarly, the Draft Planning Framework is not yet part of the military planning process. It remains a...Draft Planning Framework for Reconstruction, Stabilization, and Conflict Transformation . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 The...level from the perspective of impli- cations for the Army and its development of SSTR capabilities. The U.S. Government Draft Planning Framework for

Spatial change transformation of educational areas in Bandung

NASA Astrophysics Data System (ADS)

Yudi Permana, Asep; Wijaya, Karto

2017-12-01

Transformation is a total transfer process from a particular shape into a new figure which can be interpreted as the final stage of a changing process. Transformation, as a gradually progressive process, utilizes space and time factors becoming the aspect that greatly influences the change until reaching the ultimate stage. The changes are completed by responding to the influence of external and internal elements which will lead to a change from an early familiar form. The purpose of this research is to build theory based on phenomenon which occurs in the field as a result of space transformation process in Bandung so that it can be seen the setting adjustment of either physical or non-physical in the area becoming the city identity. The research method is qualitative research method with descriptive survey method approach. The focus of research is aimed at discrete phenomena in the field as an effort to disclose the background essence of the resulted theory formation. The study does not use a theoretical framework, yet there is a consistency in observing a discrete phenomenon of the grand tour results. The phenomenon is raised through the snowball sampling process. The process of collecting data, analyzing, and building theories is conducted jointly and iteratively within one research time range. The study results in the formation of space knowledge based on knitting and the value system of the users’ activities and the space settings. All users’ behaviors in using space are related to social, cultural, economic and creative activities in utilizing the existing space conditions. The results of this study provide an enrichment of architectural theory, planning theory and urban design theory having already existed.

Achieving a Healthy Zoning Policy in Baltimore: Results of a Health Impact Assessment of the TransForm Baltimore Zoning Code Rewrite

PubMed Central

Greiner, Amelia; Fichtenberg, Caroline M.; Feingold, Beth J.; Ellen, Jonathan M.; Jennings, Jacky M.

2013-01-01

Objectives The social determinants of health (SDH) include factors apart from genes and biology that affect population health. Zoning is an urban planning tool that influences neighborhood built environments. We describe the methods and results of a health impact assessment (HIA) of a rezoning effort in Baltimore, Maryland, called TransForm Baltimore. We highlight findings specific to physical activity, violent crime, and obesity. Methods We conducted a multistage HIA of TransForm Baltimore using HIA practice guidelines. Key informant interviews identified focus areas for the quantitative assessment. A literature review and a zoning code analysis evaluated potential impacts on neighborhood factors including physical activity, violent crime, and obesity. We estimated potential impacts in high- and low-poverty neighborhoods. The findings resulted in recommendations to improve the health-promoting potential of TransForm Baltimore. Results Mixed-use and transit-oriented development were key goals of TransForm Baltimore. Health impacts identified by stakeholders included walkability and healthy communities. For Baltimore residents, we estimated that (1) the percentage of people living in districts allowing mixed-use and off-premise alcohol outlets would nearly triple, (2) 18% would live in transit-oriented development zones, and (3) all residents would live in districts with new lighting and landscaping guidelines. Limiting the concentration of off-premise alcohol outlets represented an opportunity to address health promotion. Conclusions Changes to Baltimore's zoning code could improve population health including decreasing violent crime. HIAs are an important platform for applying SDH to public health practice. This HIA specifically linked municipal zoning policy with promoting healthier neighborhoods. PMID:24179284

Transportation planning implications of automated/connected vehicles on Texas highways.

DOT National Transportation Integrated Search

2017-04-01

This research project was focused on the transportation planning implications of automated/connected : vehicles (AV/CVs) on Texas highways. The research assessed how these potentially transformative : technologies can be included in transportation pl...

Quality initiatives: lean approach to improving performance and efficiency in a radiology department.

PubMed

Kruskal, Jonathan B; Reedy, Allen; Pascal, Laurie; Rosen, Max P; Boiselle, Phillip M

2012-01-01

Many hospital radiology departments are adopting "lean" methods developed in automobile manufacturing to improve operational efficiency, eliminate waste, and optimize the value of their services. The lean approach, which emphasizes process analysis, has particular relevance to radiology departments, which depend on a smooth flow of patients and uninterrupted equipment function for efficient operation. However, the application of lean methods to isolated problems is not likely to improve overall efficiency or to produce a sustained improvement. Instead, the authors recommend a gradual but continuous and comprehensive "lean transformation" of work philosophy and workplace culture. Fundamental principles that must consistently be put into action to achieve such a transformation include equal involvement of and equal respect for all staff members, elimination of waste, standardization of work processes, improvement of flow in all processes, use of visual cues to communicate and inform, and use of specific tools to perform targeted data collection and analysis and to implement and guide change. Many categories of lean tools are available to facilitate these tasks: value stream mapping for visualizing the current state of a process and identifying activities that add no value; root cause analysis for determining the fundamental cause of a problem; team charters for planning, guiding, and communicating about change in a specific process; management dashboards for monitoring real-time developments; and a balanced scorecard for strategic oversight and planning in the areas of finance, customer service, internal operations, and staff development. © RSNA, 2012.

Dynamic Simulation on the Installation Process of HGIS in Transformer Substation

NASA Astrophysics Data System (ADS)

Lin, Tao; Li, Shaohua; Wang, Hu; Che, Deyong; Qi, Guangcai; Yao, Jianfeng; Zhang, Qingzhe

The technological requirements of Hypid Gas Insulated Switchgear (HGIS) installation in transformer substation is high and the control points of quality is excessive. Most of the engineers and technicians in the construction enterprises are not familiar with equipments of HGIS. In order to solve these problem, equipments of HGIS is modeled on the computer by SolidWorks software. Installation process of civil foundation and closed-type equipments is optimized dynamically with virtual assemble technology. Announcements and application work are composited into animation file. Skills of modeling and simulation is tidied classify as well. The result of the visual dynamic simulation can instruct the actual construction process of HGIS to a certain degree and can promote reasonable construction planning and management. It can also improve the method and quality of staff training for electric power construction enterprises.

A spatial emergy model for Alachua County, Florida

NASA Astrophysics Data System (ADS)

Lambert, James David

A spatial model of the distribution of energy flows and storages in Alachua County, Florida, was created and used to analyze spatial patterns of energy transformation hierarchy in relation to spatial patterns of human settlement. Emergy, the available energy of one kind previously required directly or indirectly to make a product or service, was used as a measure of the quality of the different forms of energy flows and storages. Emergy provides a common unit of measure for comparing the productive contributions of natural processes with those of economic and social processes---it is an alternative to using money for measuring value. A geographic information system was used to create a spatial model and make maps that show the distribution and magnitude of different types of energy and emergy flows and storages occurring in one-hectare land units. Energy transformities were used to convert individual energy flows and storages into emergy units. Maps of transformities were created that reveal a clear spatial pattern of energy transformation hierarchy. The maps display patterns of widely-dispersed areas with lower transformity energy flows and storages, and smaller, centrally-located areas with higher transformities. Energy signature graphs and spatial unit transformities were used to characterize and compare the types and amounts of energy being consumed and stored according to land use classification, planning unit, and neighborhood categories. Emergy ratio maps and spatial unit ratios were created by dividing the values for specific emergy flows or storages by the values for other emergy flows or storages. Spatial context analysis was used to analyze the spatial distribution patterns of mean and maximum values for emergy flows and storages. The modeling method developed for this study is general and applicable to all types of landscapes and could be applied at any scale. An advantage of this general approach is that the results of other studies using this method will be directly comparable with the results of this study. The results and conclusions of this study reinforce the hypothesis that an urban landscape will develop a predictable spatial pattern that can be described in terms of a universal energy transformation hierarchy.

KSC Press Site Transformer Bldg. (K7-1205c) SWMU 074 Interim Measure Work Plan

NASA Technical Reports Server (NTRS)

Starr, A. Scott; Applegate, Joe

2014-01-01

This document presents and discusses the Interim Measure (IM) Work Plan for the Press Site Transformer Building (K7-1205C). The purpose of the proposed IM activities is to remove soil affected with polychlorinated biphenyls (PCBs) greater than the Florida Department of Environmental Protection (FDEP) residential direct-exposure Soil Cleanup Target Level (R-SCTL) of 0.5 milligrams per kilogram and encapsulate concrete exhibiting PCB concentration greater than the Toxic Substance Control Act (TSCA) threshold of 50 milligrams per kilogram.

National Research Council Dialogue to Assess Progress on NASA's Title of CRM Capability Roadmap Development: General Background and Introduction

NASA Technical Reports Server (NTRS)

Crooke, Julie A.

2005-01-01

Contents include the following: General Background and Introduction of Capability Roadmaps "Title." Agency Objective. Strategic Planning Transformation. Advanced Planning Organizational Roles. Public Involvement in Strategic Planning. Strategic Roadmaps and Schedule. Capability Roadmaps and Schedule. Purpose of NRC Review. Capability Roadmap Development (Progress to Date).

Modularized and Outcomes-Led Planning of Higher Education in Post-Apartheid South Africa.

ERIC Educational Resources Information Center

Ntshoe, I. M.

1999-01-01

Examines modularization and outcomes-based planning of higher education in South Africa as part of transforming higher education in a post-apartheid society. Discusses principles and assumptions of modularization and outcomes-based planning, identifies intended and unintended outcomes, and notes such issues as the origins of outcome-based…

National Research Council Dialogue to Assess Progress on NASA's Human Health & Support Systems Capability Roadmap Development: General Background and Introduction

NASA Technical Reports Server (NTRS)

Aikins, Jan

2005-01-01

Contents include the following: General Background and Introduction of Capability Roadmaps. Agency Objective. Strategic Planning Transformation. Advanced Planning Organizational Roles. Public Involvement in Strategic Planning. Strategic Roadmaps and Schedule. Capability Roadmaps and Schedule. Purpose of NRC Review. Capability Roadmap Development (Progress to Date).

Transforming American Education: Learning Powered by Technology. National Education Technology Plan, 2010

ERIC Educational Resources Information Center

US Department of Education, 2010

2010-01-01

This report presents the Administration's National Education Technology Plan. This plan calls for applying the advanced technologies used in everyone's daily personal and professional lives to the entire education system to improve student learning, accelerate and scale up the adoption of effective practices, and use data and information for…

Base Realignment and Closure Environmental Evaluation (BRAC EE) Fort Devens, Massachusetts

DTIC Science & Technology

1995-09-01

Not Sampled ......... 6 2.3.2 Transformer Sites Sampled ........................ 7 2.4 Soil Sampling Protocol and Analytical Program ...Evaluation (AREE) 66. The study included evaluating the current PCB Transformer Management Program administered by the Fort Devens Environmental Management...Office (EMO), the Fort Devens Spill Contingency Plan, and the ongoing transformer inspection program . Personnel in both the Fort Devens EMO and the Fort

An accurate algorithm to match imperfectly matched images for lung tumor detection without markers

PubMed Central

Rozario, Timothy; Bereg, Sergey; Yan, Yulong; Chiu, Tsuicheng; Liu, Honghuan; Kearney, Vasant; Jiang, Lan

2015-01-01

In order to locate lung tumors on kV projection images without internal markers, digitally reconstructed radiographs (DRRs) are created and compared with projection images. However, lung tumors always move due to respiration and their locations change on projection images while they are static on DRRs. In addition, global image intensity discrepancies exist between DRRs and projections due to their different image orientations, scattering, and noises. This adversely affects comparison accuracy. A simple but efficient comparison algorithm is reported to match imperfectly matched projection images and DRRs. The kV projection images were matched with different DRRs in two steps. Preprocessing was performed in advance to generate two sets of DRRs. The tumors were removed from the planning 3D CT for a single phase of planning 4D CT images using planning contours of tumors. DRRs of background and DRRs of tumors were generated separately for every projection angle. The first step was to match projection images with DRRs of background signals. This method divided global images into a matrix of small tiles and similarities were evaluated by calculating normalized cross‐correlation (NCC) between corresponding tiles on projections and DRRs. The tile configuration (tile locations) was automatically optimized to keep the tumor within a single projection tile that had a bad matching with the corresponding DRR tile. A pixel‐based linear transformation was determined by linear interpolations of tile transformation results obtained during tile matching. The background DRRs were transformed to the projection image level and subtracted from it. The resulting subtracted image now contained only the tumor. The second step was to register DRRs of tumors to the subtracted image to locate the tumor. This method was successfully applied to kV fluoro images (about 1000 images) acquired on a Vero (BrainLAB) for dynamic tumor tracking on phantom studies. Radiation opaque markers were implanted and used as ground truth for tumor positions. Although other organs and bony structures introduced strong signals superimposed on tumors at some angles, this method accurately located tumors on every projection over 12 gantry angles. The maximum error was less than 2.2 mm, while the total average error was less than 0.9 mm. This algorithm was capable of detecting tumors without markers, despite strong background signals. PACS numbers: 87.57.cj, 87.57.cp87.57.nj, 87.57.np, 87.57.Q‐, 87.59.bf, 87.63.lm

Transforming American Education

ERIC Educational Resources Information Center

Horn, Michael B.; Mackey, Katherine

2011-01-01

In this article the authors accept as a given the National Education Technology Plan's vision of a transformed education system powered by technology such that learners receive personalized and engaging learning experiences, and where assessment, teaching, infrastructure, and productivity are redefined. The article analyzes this vision of a…

Global positioning systems for personal travel surveys : Lexington area travel data collection test

DOT National Transportation Integrated Search

1986-12-01

The urban transportation planning process is undergoing critical transformations. Of particular interest is the emergence of private sector involvement in the planning, management, financing, construction of transportation systems and provision of tr...

Transforming transportation through connectivity : ITS strategic research plan, 2010-2014 progress update, 2012

DOT National Transportation Integrated Search

2012-10-31

This document updates the Intelligent Transportation Systems Strategic Research Plan, 20102014, a focused research agenda whose goal is to deliver the foundational systems, technologies, and applications that provide transportation connectivity to...

Generation of synthetic CT data using patient specific daily MR image data and image registration

NASA Astrophysics Data System (ADS)

Melanie Kraus, Kim; Jäkel, Oliver; Niebuhr, Nina I.; Pfaffenberger, Asja

2017-02-01

To fully exploit the advantages of magnetic resonance imaging (MRI) for radiotherapy (RT) treatment planning, a method is required to overcome the problem of lacking electron density information. We aim to establish and evaluate a new method for computed tomography (CT) data generation based on MRI and image registration. The thereby generated CT data is used for dose accumulation. We developed a process flow based on an initial pair of rigidly co-registered CT and T2-weighted MR image representing the same anatomical situation. Deformable image registration using anatomical landmarks is performed between the initial MRI data and daily MR images. The resulting transformation is applied to the initial CT, thus fractional CT data is generated. Furthermore, the dose for a photon intensity modulated RT (IMRT) or intensity modulated proton therapy (IMPT) plan is calculated on the generated fractional CT and accumulated on the initial CT via inverse transformation. The method is evaluated by the use of phantom CT and MRI data. Quantitative validation is performed by evaluation of the mean absolute error (MAE) between the measured and the generated CT. The effect on dose accumulation is examined by means of dose-volume parameters. One patient case is presented to demonstrate the applicability of the method introduced here. Overall, CT data derivation lead to MAEs with a median of 37.0 HU ranging from 29.9 to 66.6 HU for all investigated tissues. The accuracy of image registration showed to be limited in the case of unexpected air cavities and at tissue boundaries. The comparisons of dose distributions based on measured and generated CT data agree well with the published literature. Differences in dose volume parameters kept within 1.6% and 3.2% for photon and proton RT, respectively. The method presented here is particularly suited for application in adaptive RT in current clinical routine, since only minor additional technical equipment is required.

The Drive towards Sustainable Health Systems Needs an Alignment: Where are the Innovations in Health Systems Planning?

PubMed

Murphy, Gail Tomblin; Birch, Stephen; MacKenzie, Adrian; Rigby, Janet; Purkis, Mary Ellen

2017-01-01

Clarifying the healthcare innovation agenda is critical in order to advance the impact of system innovations. As part of this agenda-setting it is important to address the four conditions within which innovations can enhance system sustainability: 1) the innovation agenda reflects and is aligned with healthcare objectives and policy; 2) planning methodologies for services, workforce and funding are aligned with healthcare objectives and policy; 3) innovations in services are accommodated in systems through innovations in policy, planning and funding; and 4) innovations are systematically monitored and evaluated. In order to illustrate these conditions, the authors present a case study of an evaluation of one Canadian Health Authority's efforts to transform healthcare delivery. This case study reveals that aligning innovations in policy, planning, funding and health services is critical to transforming health systems and that, in the absence of such alignment, sustainable health systems are difficult to achieve.

Discrete fourier transform (DFT) analysis for applications using iterative transform methods

NASA Technical Reports Server (NTRS)

Dean, Bruce H. (Inventor)

2012-01-01

According to various embodiments, a method is provided for determining aberration data for an optical system. The method comprises collecting a data signal, and generating a pre-transformation algorithm. The data is pre-transformed by multiplying the data with the pre-transformation algorithm. A discrete Fourier transform of the pre-transformed data is performed in an iterative loop. The method further comprises back-transforming the data to generate aberration data.

Evidence for rare capsular switching in Streptococcus agalactiae.

PubMed

Martins, Elisabete Raquel; Melo-Cristino, José; Ramirez, Mário

2010-03-01

The polysaccharide capsule is a major antigenic factor in Streptococcus agalactiae (Lancefield group B streptococcus [GBS]). Previous observations suggest that exchange of capsular loci is likely to occur rather frequently in GBS, even though GBS is not known to be naturally transformable. We sought to identify and characterize putative capsular switching events, by means of a combination of phenotypic and genotypic methods, including pulsed-field gel electrophoretic profiling, multilocus sequence typing, and surface protein and pilus gene profiling. We show that capsular switching by horizontal gene transfer is not as frequent as previously suggested. Serotyping errors may be the main reason behind the overestimation of capsule switching, since phenotypic techniques are prone to errors of interpretation. The identified putative capsular transformants involved the acquisition of the entire capsular locus and were not restricted to the serotype-specific central genes, the previously suggested main mechanism underlying capsular switching. Our data, while questioning the frequency of capsular switching, provide clear evidence for in vivo capsular transformation in S. agalactiae, which may be of critical importance in planning future vaccination strategies against this pathogen.

Evidence for Rare Capsular Switching in Streptococcus agalactiae▿

PubMed Central

Martins, Elisabete Raquel; Melo-Cristino, José; Ramirez, Mário

2010-01-01

The polysaccharide capsule is a major antigenic factor in Streptococcus agalactiae (Lancefield group B streptococcus [GBS]). Previous observations suggest that exchange of capsular loci is likely to occur rather frequently in GBS, even though GBS is not known to be naturally transformable. We sought to identify and characterize putative capsular switching events, by means of a combination of phenotypic and genotypic methods, including pulsed-field gel electrophoretic profiling, multilocus sequence typing, and surface protein and pilus gene profiling. We show that capsular switching by horizontal gene transfer is not as frequent as previously suggested. Serotyping errors may be the main reason behind the overestimation of capsule switching, since phenotypic techniques are prone to errors of interpretation. The identified putative capsular transformants involved the acquisition of the entire capsular locus and were not restricted to the serotype-specific central genes, the previously suggested main mechanism underlying capsular switching. Our data, while questioning the frequency of capsular switching, provide clear evidence for in vivo capsular transformation in S. agalactiae, which may be of critical importance in planning future vaccination strategies against this pathogen. PMID:20023016

Transformational Leadership in the Planning of a Doctoral Program.

ERIC Educational Resources Information Center

Martinez, Bobby J.; Slater, Charles L.

2000-01-01

The process of developing a doctoral program at the University of the Incarnate Word demonstrates the use of both transformational leadership (empowerment, advocacy, reconciliation) and transactional leadership (power brokering, making legitimate decisions). The contemporary environment needs multiple leaders who exercise different types of…

An Exploration of Social Justice Intent in Photovoice Research Studies: From 2008 to 2013

PubMed Central

Sanon, Marie-Anne; Evans-Agnew, Robin A.; Boutain, Doris M.

2014-01-01

In an age where digital images are omnipresent, the use of participant photography in qualitative research has become accessible and commonplace. Yet, scant attention is paid to the social justice impact of photovoice among studies that have used this innovative method as a way to promote social justice. There is a need to review this method to understand its contributions and possibilities. This literature review of photovoice research studies 1) explores whether authors implicitly or explicitly related the methodologies to their aims of promoting social justice (methodology-method fit), and 2) outlines the social justice research impact of photovoice findings using the framework of social justice awareness, amelioration, and transformation. PubMed, Scopus, PsycINFO, and Web of Science databases were searched from the years 2008–2013 using the keywords: photovoice; photonovella; photovoice and social justice; and photovoice and participatory action research. Of the 30 research studies reviewed, only thirteen identified an underlying methodology guiding the photovoice method. The social justice impacts emphasized were more related to social justice awareness (n= 30) than amelioration (n= 11) or transformation (n=3). Future researchers using photovoice as a way to promote social justice are encouraged to assess and plan for the social justice impact desired. PMID:24602185

An exploration of social justice intent in photovoice research studies from 2008 to 2013.

PubMed

Sanon, Marie-Anne; Evans-Agnew, Robin A; Boutain, Doris M

2014-09-01

In an age where digital images are omnipresent, the use of participant photography in qualitative research has become accessible and commonplace. Yet, scant attention is paid to the social justice impact of photovoice amongst studies that have used this innovative method as a way to promote social justice. There is a need to review this method to understand its contributions and possibilities. This literature review of photovoice research studies (i) explores whether authors implicitly or explicitly related the methodologies to their aims of promoting social justice (methodology-method fit) and (ii) outlines the social justice research impact of photovoice findings using the framework of social justice awareness, amelioration and transformation. PubMed, Scopus, PsycINFO and Web of Science databases were searched from the years 2008-13 using the following keywords: photovoice; photonovella; photovoice and social justice; and photovoice and participatory action research. Of the 30 research studies reviewed, only thirteen identified an underlying methodology guiding the photovoice method. The social justice impacts emphasized were more related to social justice awareness (n = 30) than amelioration (n = 11) or transformation (n = 3). Future researchers using photovoice as a way to promote social justice are encouraged to assess and plan for the social justice impact desired. © 2014 John Wiley & Sons Ltd.

Legal Challenges and Pitfalls for Start-up Companies - 48 Common Questions and Answers.

PubMed

Staehelin, Matthias

2014-12-01

Transforming a business idea into reality requires a legal implementation plan. The following 48 questions and answers address key issues that typically arise in start-up situations. Early planning can help avoid costly mistakes.

The Agenda for Strategic Planning in Social Institutions Such as Government, Post-Secondary Education and Corporations: An Element of the Accreditation Self-Study at College of the Mainland.

ERIC Educational Resources Information Center

Vaughan, Jerry L., Sr.

This paper presents a discussion of strategic planning within social institutions and provides a planning agenda that focuses on modern trends, forecasts, and projections. First, the background of the strategic planning process is reviewed, and historical changes in the nature of modern technology are delineated, including a transformation in…

Next Generation Air Transportation System : progress and challenges in planning and implementing the transformation of the National Airspace System : testimony before the Subcommittee on Aviation, Committee on Transportation and Infrastructure, U.S. Senat

DOT National Transportation Integrated Search

2010-04-21

To prepare for future air traffic growth, the Federal Aviation Administration (FAA), including its Joint Planning and Development Office (JPDO) and Air Traffic Organization, is planning and implementing the Next Generation Air Transportation System (...

Regulating and Negotiating Linguistic Diversity: Top-Down and Bottom-Up Language Planning in the Moroccan City

ERIC Educational Resources Information Center

Hassa, Samira

2012-01-01

This study examines language planning as displayed in street names, advertising posters, billboards, and supermarket product displays in three Moroccan cities: Casablanca, Fes, and Rabat. The study reveals somewhat confusing language planning stemming from on-going political, economic, and social transformation in Morocco. More than 50 years after…

Strategies for Action: An Outline of Factors Which Influence Decisions on Program Plans.

ERIC Educational Resources Information Center

Bogue, E. G.

This paper discusses strategies which can help the admissions officer/registrar be more effective in having his program plans transformed into reality. The program planning process is considered from three prospectives beginning with a brief discussion of the current state of program development in higher education. It is conjectured that the…

Alabama Education Report Card, 2012-2013: A Year in Review

ERIC Educational Resources Information Center

Alabama State Department of Education, 2014

2014-01-01

Beginning in January of 2012, the Alabama State Board of Education embarked on a bold and transformation plan for K-12 public education known as PLAN 2020. Foundational to this plan was a new definition of a successful and prepared high school graduate informed by community colleges, institutions of higher education, and business and industry,…

National Research Council Dialogue to Assess Progress on NASA's Advanced Modeling, Simulation and Analysis Capability and Systems Engineering Capability Roadmap Development

NASA Technical Reports Server (NTRS)

Aikins, Jan

2005-01-01

Contents include the following: General Background and Introduction of Capability Roadmaps. Agency Objective. Strategic Planning Transformation. Advanced Planning Organizational Roles. Public Involvement in Strategic Planning. Strategic Roadmaps and Schedule. Capability Roadmaps and Schedule. Purpose of NRC Review. Capability Roadmap Development (Progress to Date).

Managed care innovation and new product development.

PubMed

Clark, C S; Schuster, T B

1994-01-01

This article explores recent innovative activity by managed care payor plans nationwide with particular emphasis on emerging, new relationships between the plans and their purchasers, enrollees, provider panels, and competitors. Because they already practice what advocates of health care reform are now preaching, many managed care plans are leading the charge to transform our health care delivery and financing systems.

Rehabilitation centers in change: participatory methods for managing redesign and renovation.

PubMed

Lahtinen, Marjaana; Nenonen, Suvi; Rasila, Heidi; Lehtelä, Jouni; Ruohomäki, Virpi; Reijula, Kari

2014-01-01

The aim of this article is to describe a set of participatory methods that we have either developed or modified for developing future work and service environments to better suit renewable rehabilitation processes. We discuss the methods in a larger framework of change process model and participatory design. Rehabilitation organizations are currently in transition; customer groups, financing, services, and the processes of rehabilitation centers are changing. The pressure for change challenges the centers to develop both their processes and facilities. There is a need for methods that support change management. Four participatory methods were developed: future workshop, change survey, multi-method assessment tool, and participatory design generator cards. They were tested and evaluated in three rehabilitation centers at the different phases of their change process. The developed methods were considered useful in creating a mutual understanding of the change goals between different stakeholders, providing a good picture of the work community's attitudes toward the change, forming an integrated overview of the built and perceived environment, inspiring new solutions, and supporting the management in steering the change process. The change process model described in this article serves as a practical framework that combined the viewpoints of organizational and facility development. However, participatory design continues to face challenges concerning communication between different stakeholders, and further development of the methods and processes is still needed. Intervention studies could provide data on the success factors that enhance the transformations in the rehabilitation sector. Design process, methodology, organizational transformation, planning, renovation.

Risky Group Decision-Making Method for Distribution Grid Planning

NASA Astrophysics Data System (ADS)

Li, Cunbin; Yuan, Jiahang; Qi, Zhiqiang

2015-12-01

With rapid speed on electricity using and increasing in renewable energy, more and more research pay attention on distribution grid planning. For the drawbacks of existing research, this paper proposes a new risky group decision-making method for distribution grid planning. Firstly, a mixing index system with qualitative and quantitative indices is built. On the basis of considering the fuzziness of language evaluation, choose cloud model to realize "quantitative to qualitative" transformation and construct interval numbers decision matrices according to the "3En" principle. An m-dimensional interval numbers decision vector is regarded as super cuboids in m-dimensional attributes space, using two-level orthogonal experiment to arrange points uniformly and dispersedly. The numbers of points are assured by testing numbers of two-level orthogonal arrays and these points compose of distribution points set to stand for decision-making project. In order to eliminate the influence of correlation among indices, Mahalanobis distance is used to calculate the distance from each solutions to others which means that dynamic solutions are viewed as the reference. Secondly, due to the decision-maker's attitude can affect the results, this paper defines the prospect value function based on SNR which is from Mahalanobis-Taguchi system and attains the comprehensive prospect value of each program as well as the order. At last, the validity and reliability of this method is illustrated by examples which prove the method is more valuable and superiority than the other.

Selection and Evaluation of Priority Domains in Global Energy Internet Standard Development Based on Technology Foresight

NASA Astrophysics Data System (ADS)

Jin, Yang; Ciwei, Gao; Jing, Zhang; Min, Sun; Jie, Yu

2017-05-01

The selection and evaluation of priority domains in Global Energy Internet standard development will help to break through limits of national investment, thus priority will be given to standardizing technical areas with highest urgency and feasibility. Therefore, in this paper, the process of Delphi survey based on technology foresight is put forward, the evaluation index system of priority domains is established, and the index calculation method is determined. Afterwards, statistical method is used to evaluate the alternative domains. Finally the top four priority domains are determined as follows: Interconnected Network Planning and Simulation Analysis, Interconnected Network Safety Control and Protection, Intelligent Power Transmission and Transformation, and Internet of Things.

Next generation air transportation system : issues associated with midterm implementation of capabilities and full system transformation.

DOT National Transportation Integrated Search

2009-03-01

To prepare for forecasted air traffic : growth, the Federal Aviation : Administration (FAA), including its : Joint Planning and Development : Office (JPDO) and Air Traffic : Organization (ATO), is planning for : and implementing the Next : Generation...

Nurse Leadership and Informatics Competencies: Shaping Transformation of Professional Practice.

PubMed

Kennedy, Margaret Ann; Moen, Anne

2017-01-01

Nurse leaders must demonstrate capacities and develop specific informatics competencies in order to provide meaningful leadership and support ongoing transformation of the healthcare system. Concurrently, staff informatics competencies must be planned and fostered to support critical principles of transformation and patient safety in practice, advance evidence-informed practice, and enable nursing to flourish in complex digital environments across the healthcare continuum. In addition to nurse leader competencies, two key aspects of leadership and informatics competencies will be addressed in this chapter - namely, the transformation of health care and preparation of the nursing workforce.

[Study on different extracts of Chrysanthemum indicum by Fourier transform infrared spectroscopy].

PubMed

Zhang, Yan-Ling; Xia, Yuan; Tsogt; Zhou, Qun; Sun, Su-Qin

2012-12-01

According to the macro-fingerprint characteristic of infrared spectroscopy, Fourier transform infrared spectroscopy and second-derivative infrared spectroscopy were used to analyze the extracts of chrysanthemum indicum L. by different solvents. It was speculated preliminarily that the main component of petroleum ether extract was long chain fatty acids (esters) and terpenes of small molecules, ethyl acetate extract contains terpenes and flavonoids mainly, ethanol and 95% ethanol extract was mainly composed of flavonoids and flavonoid glycosides, and deionized water extract contains polysaccharides and tannins mainly. Besides, the content of flavonoids in ethanol extract is the highest by comparison of the infrared spectroscopy of different extracts with that of buddleoside. Thus, the infrared spectroscopy can analyze directly the extracts of traditional Chinese medicines, recognize the main ingredient preliminarily, and then supply directional reference for further planning the extract scheme and detection methods.

Design of a compact static Fourier transform spectrometer in integrated optics based on a leaky loop structure.

PubMed

Martin, Bruno; Morand, Alain; Benech, Pierre; Leblond, Gregory; Blaize, Sylvain; Lerondel, Gilles; Royer, Pascal; Kern, Pierre; Le Coarer, Etienne

2009-01-15

A compact static Fourier transform spectrometer for integrated optics is proposed. It is based on a plane leaky loop structure combined with a plane waveguide. The interference pattern produced in the loop structure leaks outside of it and is guided in the plane waveguide to the photodetector array. This configuration allows one to control the shape of the field pattern at the end of the plane waveguide. A large fringe pattern with a high interference fringe contrast is obtained. A two-dimensional model based on an aperiodic Fourier modal method is used to modelize the coupling between the bent and the plane waveguides, completed with the Helmholtz-Kirchhoff propagation. This concept gives access to plan and compact spectrometers requiring only a single low-cost realization process step. The simulation has been done to realize a spectrometer in glass integrated optics (Deltalambda=6.1 nm at 1500 nm).

Integration of Visual and Joint Information to Enable Linear Reaching Motions

NASA Astrophysics Data System (ADS)

Eberle, Henry; Nasuto, Slawomir J.; Hayashi, Yoshikatsu

2017-01-01

A new dynamics-driven control law was developed for a robot arm, based on the feedback control law which uses the linear transformation directly from work space to joint space. This was validated using a simulation of a two-joint planar robot arm and an optimisation algorithm was used to find the optimum matrix to generate straight trajectories of the end-effector in the work space. We found that this linear matrix can be decomposed into the rotation matrix representing the orientation of the goal direction and the joint relation matrix (MJRM) representing the joint response to errors in the Cartesian work space. The decomposition of the linear matrix indicates the separation of path planning in terms of the direction of the reaching motion and the synergies of joint coordination. Once the MJRM is numerically obtained, the feedfoward planning of reaching direction allows us to provide asymptotically stable, linear trajectories in the entire work space through rotational transformation, completely avoiding the use of inverse kinematics. Our dynamics-driven control law suggests an interesting framework for interpreting human reaching motion control alternative to the dominant inverse method based explanations, avoiding expensive computation of the inverse kinematics and the point-to-point control along the desired trajectories.

Nonlinear Prediction Model for Hydrologic Time Series Based on Wavelet Decomposition

NASA Astrophysics Data System (ADS)

Kwon, H.; Khalil, A.; Brown, C.; Lall, U.; Ahn, H.; Moon, Y.

2005-12-01

Traditionally forecasting and characterizations of hydrologic systems is performed utilizing many techniques. Stochastic linear methods such as AR and ARIMA and nonlinear ones such as statistical learning theory based tools have been extensively used. The common difficulty to all methods is the determination of sufficient and necessary information and predictors for a successful prediction. Relationships between hydrologic variables are often highly nonlinear and interrelated across the temporal scale. A new hybrid approach is proposed for the simulation of hydrologic time series combining both the wavelet transform and the nonlinear model. The present model employs some merits of wavelet transform and nonlinear time series model. The Wavelet Transform is adopted to decompose a hydrologic nonlinear process into a set of mono-component signals, which are simulated by nonlinear model. The hybrid methodology is formulated in a manner to improve the accuracy of a long term forecasting. The proposed hybrid model yields much better results in terms of capturing and reproducing the time-frequency properties of the system at hand. Prediction results are promising when compared to traditional univariate time series models. An application of the plausibility of the proposed methodology is provided and the results conclude that wavelet based time series model can be utilized for simulating and forecasting of hydrologic variable reasonably well. This will ultimately serve the purpose of integrated water resources planning and management.

3-D surface profilometry based on modulation measurement by applying wavelet transform method

NASA Astrophysics Data System (ADS)

Zhong, Min; Chen, Feng; Xiao, Chao; Wei, Yongchao

2017-01-01

A new analysis of 3-D surface profilometry based on modulation measurement technique by the application of Wavelet Transform method is proposed. As a tool excelling for its multi-resolution and localization in the time and frequency domains, Wavelet Transform method with good localized time-frequency analysis ability and effective de-noizing capacity can extract the modulation distribution more accurately than Fourier Transform method. Especially for the analysis of complex object, more details of the measured object can be well remained. In this paper, the theoretical derivation of Wavelet Transform method that obtains the modulation values from a captured fringe pattern is given. Both computer simulation and elementary experiment are used to show the validity of the proposed method by making a comparison with the results of Fourier Transform method. The results show that the Wavelet Transform method has a better performance than the Fourier Transform method in modulation values retrieval.

Integration of scheduling and discrete event simulation systems to improve production flow planning

NASA Astrophysics Data System (ADS)

Krenczyk, D.; Paprocka, I.; Kempa, W. M.; Grabowik, C.; Kalinowski, K.

2016-08-01

The increased availability of data and computer-aided technologies such as MRPI/II, ERP and MES system, allowing producers to be more adaptive to market dynamics and to improve production scheduling. Integration of production scheduling and computer modelling, simulation and visualization systems can be useful in the analysis of production system constraints related to the efficiency of manufacturing systems. A integration methodology based on semi-automatic model generation method for eliminating problems associated with complexity of the model and labour-intensive and time-consuming process of simulation model creation is proposed. Data mapping and data transformation techniques for the proposed method have been applied. This approach has been illustrated through examples of practical implementation of the proposed method using KbRS scheduling system and Enterprise Dynamics simulation system.

Symbolic feature detection for image understanding

NASA Astrophysics Data System (ADS)

Aslan, Sinem; Akgül, Ceyhun Burak; Sankur, Bülent

2014-03-01

In this study we propose a model-driven codebook generation method used to assign probability scores to pixels in order to represent underlying local shapes they reside in. In the first version of the symbol library we limited ourselves to photometric and similarity transformations applied on eight prototypical shapes of flat plateau , ramp, valley, ridge, circular and elliptic respectively pit and hill and used randomized decision forest as the statistical classifier to compute shape class ambiguity of each pixel. We achieved90% accuracy in identification of known objects from alternate views, however, we could not outperform texture, global and local shape methods, but only color-based method in recognition of unknown objects. We present a progress plan to be accomplished as a future work to improve the proposed approach further.

The Nature of Transformation: Environmental Adult Education. Second Edition.

ERIC Educational Resources Information Center

Clover, Darlene E.; Follen, Shirley; Hall, Budd

This document, which is intended to assist environmental, health, and community-based educators in Canada and elsewhere, discusses the process of drawing upon the theories and methodologies of transformative learning to plan adult environmental education workshops emphasizing the theme of socio-environmental change. The following are among the…

Transformation of the Schoolhouse. Annual Report for 1969.

ERIC Educational Resources Information Center

Coughlin, Gaila, Ed.

This report reviews some of the more important educational innovations that have transformed the arrangement of space and design of the schoolhouse environment. Design, structural, and functional features are described for open plan schools (schools without interior walls). Consideration is given to the use of performance specifications in the…

Strategic Planning in Ireland's Institutes of Technology

ERIC Educational Resources Information Center

Elwood, Larry; Rainnie, Al

2012-01-01

This article focuses upon Ireland's institute of technology sector, which has been transformed from a 1970s technical orientation to its broader current role of research and higher education provision. The transformational shifts experienced by institutes over the previous three decades have been profound: increased autonomy, new managerial and…

Network-based simulation of aircraft at gates in airport terminals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cheng, Y.

1998-03-01

Simulation is becoming an essential tool for planning, design, and management of airport facilities. A simulation of aircraft at gates at an airport can be applied for various periodically performed applications, relating to the dynamic behavior of aircraft at gates in airport terminals for analyses, evaluations, and decision supports. Conventionally, such simulations are implemented using an event-driven method. For a more efficient simulation, this paper proposes a network-based method. The basic idea is to transform all the sequence constraint relations of aircraft at gates into a network. The simulation is done by calculating the longest path to all the nodesmore » in the network. The effect of the algorithm of the proposed method has been examined by experiments, and the superiority of the proposed method over the event-driven method is revealed through comprehensive comparisons of their overall simulation performance.« less

Next generation air transportation system : status of transformation and issues associated with midterm implementation of capabilities.

DOT National Transportation Integrated Search

2009-03-01

"To prepare for forecasted air traffic growth, the Federal Aviation Administration (FAA), including its Joint Planning and Development Office (JPDO) and Air Traffic Organization (ATO), is planning for and implementing the Next Generation Air Transpor...

Person-Centred Reviews as a Mechanism for Planning the Post-School Transition of Young People with Intellectual Disability

ERIC Educational Resources Information Center

Kaehne, A.; Beyer, S.

2014-01-01

Background: Person-centred planning has played a key role in the transformation of intellectual disabilities services for more than a decade. The literature has identified clear advantages for service users when service delivery is planned around the individual rather than the user is made to fit into service structures. Researchers however have…

Educational Planning and Social Responsibility: Eleven Years of Mega Planning at the Sonora Institute of Technology (ITSON)

ERIC Educational Resources Information Center

Guerra, Ingrid J.; Rodriguez, Gonzalo

2005-01-01

The Instituto Tecnologico de Sonora (ITSON), a public and autonomous university in Cuidad Obregon, Sonora in Mexico has, since its inception, maintained a commitment to society and public service. To transform this commitment into valued results, it has used Mega Planning as its framework over the last eleven years. This article illustrates the…

Acting Out the Great Books: A Case Study of How the Implemented Curriculum Can Differ from the Planned Curriculum.

ERIC Educational Resources Information Center

Wortham, Stanton

This paper reports on a study of the complex ways a planned curriculum can get transformed in practice. The analysis also illustrates how the implemented curriculum can have moral and political significance, in ways that critics of the planned curriculum might not foresee. "Participant example," an actual or hypothetical event in which…

National Research Council Dialogue to Assess Progesss on NASA's Human Exploration Systems and Mobility Capability Roadmap Development: General Background and Introduction

NASA Technical Reports Server (NTRS)

Inman, Thomas

2005-01-01

General Background and Introduction of Capability Roadmaps: Agency Objective. Strategic Planning Transformation. Advanced Planning Organizational Roles. Public Involvement in Strategic Planning. Strategic Roadmaps and Schedule. Capability Roadmaps and Schedule. Technology and Capability Readiness Levels. Relationships Between Roadmaps. Purpose of NRC Review. Capability Roadmap Development (Team Progress to Date).

Multimodal Logistics Network Design over Planning Horizon through a Hybrid Meta-Heuristic Approach

NASA Astrophysics Data System (ADS)

Shimizu, Yoshiaki; Yamazaki, Yoshihiro; Wada, Takeshi

Logistics has been acknowledged increasingly as a key issue of supply chain management to improve business efficiency under global competition and diversified customer demands. This study aims at improving a quality of strategic decision making associated with dynamic natures in logistics network optimization. Especially, noticing an importance to concern with a multimodal logistics under multiterms, we have extended a previous approach termed hybrid tabu search (HybTS). The attempt intends to deploy a strategic planning more concretely so that the strategic plan can link to an operational decision making. The idea refers to a smart extension of the HybTS to solve a dynamic mixed integer programming problem. It is a two-level iterative method composed of a sophisticated tabu search for the location problem at the upper level and a graph algorithm for the route selection at the lower level. To keep efficiency while coping with the resulting extremely large-scale problem, we invented a systematic procedure to transform the original linear program at the lower-level into a minimum cost flow problem solvable by the graph algorithm. Through numerical experiments, we verified the proposed method outperformed the commercial software. The results indicate the proposed approach can make the conventional strategic decision much more practical and is promising for real world applications.

TU-C-17A-05: Dose Domain Optimization of MLC Leaf Patterns for Highly Complicated 4Ï€ IMRT Plans

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nguyen, D; Yu, V; Ruan, D

Purpose: Highly conformal non-coplanar 4π radiotherapy plans typically require more than 20 intensity-modulated fields to deliver. A novel method to calculate multileaf collimator (MLC) leaf patterns is introduced to maximize delivery efficiency, accuracy and plan quality. Methods: 4 GBM patients, with a prescription dose of 59.4 Gy or 60 Gy, were evaluated using the 4π algorithm using 20 beams. The MLC calculation utilized a least square minimization of the dose distribution, with an anisotropic total variation regularization term to encourage piecewise continuity in the fluence maps. Transforming the fluence to the dose domain required multiplying the fluence with a sparsemore » matrix. Exploiting this property made it feasible to solve the problem using CVX, a MATLAB-based convex modeling framework. The fluence was stratified into even step sizes, and the MLC segments, limited to 300, were calculated. The patients studied were replanned using Eclipse with the same beam angles. Results: Compared to the original 4π plan, the stratified 4π plan increased the maximum/mean dose for, in Gy, by 1.0/0.0 (brainstem), 0.5/0.2 (chiasm), 0.0/0.0 (spinal cord), 1.9/0.3 (L eye), 0.7/0.2 (R eye), 0.4/0.4 (L lens), 0.3/0.3 (R lens), 1.0/0.8 (L Optical Nerve), 0.5/0.3 (R Optical Nerve), 0.3/0.2 (L Cochlea), 0.1/0.1 (R Cochlea), 4.6/0.2 (brain), 2.4/0.1 (brain-PTV), 5.1/0.9 (PTV). Compared to Eclipse, which generated an average of 607 segments, the stratified plan reduced (−) or increased (+) the maximum/mean dose, in Gy, by −10.2/−4.1 (brainstem), −10.5/−8.9 (chiasm), +0.0/−0.1 (spinal cord), −4.9/−3.4 (L eye), −4.1/−2.5 (R eye), −2.8/−2.7 (L lens), −2.1/−1.9 (R lens), −7.6/−6.5 (L Optical Nerve), −8.9/−6.1 (R Optical Nerve), −1.3/−1.9 (L Cochlea), −1.8/−1.8 (R Cochlea), +1.7/−2.1 (brain), +3.2/−2.6 (brain-PTV), +1.8/+0.3 Gy (PTV. The stratified plan was also more homogeneous in the PTV. Conclusion: This novel solver can transform complicated fluence maps into significantly fewer deliverable MLC segments than the commercial system while achieving superior dosimetry. Funding support partially contributed by Varian.« less

Frameless fractionated stereotactic radiation therapy of intracranial lesions: impact of cone beam CT based setup correction on dose distribution

PubMed Central

2013-01-01

Background The purpose of this study was to evaluate the impact of Cone Beam CT (CBCT) based setup correction on total dose distributions in fractionated frameless stereotactic radiation therapy of intracranial lesions. Methods Ten patients with intracranial lesions treated with 30 Gy in 6 fractions were included in this study. Treatment planning was performed with Oncentra® for a SynergyS® (Elekta Ltd, Crawley, UK) linear accelerator with XVI® Cone Beam CT, and HexaPOD™ couch top. Patients were immobilized by thermoplastic masks (BrainLab, Reuther). After initial patient setup with respect to lasers, a CBCT study was acquired and registered to the planning CT (PL-CT) study. Patient positioning was corrected according to the correction values (translational, rotational) calculated by the XVI® system. Afterwards a second CBCT study was acquired and registered to the PL-CT to confirm the accuracy of the corrections. An in-house developed software was used for rigid transformation of the PL-CT to the CBCT geometry, and dose calculations for each fraction were performed on the transformed CT. The total dose distribution was achieved by back-transformation and summation of the dose distributions of each fraction. Dose distributions based on PL-CT, CBCT (laser set-up), and final CBCT were compared to assess the influence of setup inaccuracies. Results The mean displacement vector, calculated over all treatments, was reduced from (4.3 ± 1.3) mm for laser based setup to (0.5 ± 0.2) mm if CBCT corrections were applied. The mean rotational errors around the medial-lateral, superior-inferior, anterior-posterior axis were reduced from (−0.1 ± 1.4)°, (0.1 ± 1.2)° and (−0.2 ± 1.0)°, to (0.04 ± 0.4)°, (0.01 ± 0.4)° and (0.02 ± 0.3)°. As a consequence the mean deviation between planned and delivered dose in the planning target volume (PTV) could be reduced from 12.3% to 0.4% for D95 and from 5.9% to 0.1% for Dav. Maximum deviation was reduced from 31.8% to 0.8% for D95, and from 20.4% to 0.1% for Dav. Conclusion Real dose distributions differ substantially from planned dose distributions, if setup is performed according to lasers only. Thermoplasic masks combined with a daily CBCT enabled a sufficient accuracy in dose distribution. PMID:23800172

Family planning and family vision in mothers after diagnosis of a child with autism spectrum disorder

PubMed Central

Navot, Noa; Jorgenson, Alicia Grattan; Stoep, Ann Vander; Toth, Karen; Webb, Sara Jane

2016-01-01

The diagnosis of a child with autism has short- and long-term impacts on family functioning. With early diagnosis, the diagnostic process is likely to co-occur with family planning decisions, yet little is known about how parents navigate this process. This study explores family planning decision making process among mothers of young children with autism spectrum disorder in the United States, by understanding the transformation in family vision before and after the diagnosis. A total of 22 mothers of first born children, diagnosed with autism between 2 and 4 years of age, were interviewed about family vision prior to and after their child’s diagnosis. Grounded Theory method was used for data analysis. Findings indicated that coherence of early family vision, maternal cognitive flexibility, and maternal responses to diagnosis were highly influential in future family planning decisions. The decision to have additional children reflected a high level of adaptability built upon a solid internalized family model and a flexible approach to life. Decision to stop childrearing reflected a relatively less coherent family model and more rigid cognitive style followed by ongoing hardship managing life after the diagnosis. This report may be useful for health-care providers in enhancing therapeutic alliance and guiding family planning counseling. PMID:26395237

Family planning and family vision in mothers after diagnosis of a child with autism spectrum disorder.

PubMed

Navot, Noa; Jorgenson, Alicia Grattan; Vander Stoep, Ann; Toth, Karen; Webb, Sara Jane

2016-07-01

The diagnosis of a child with autism has short- and long-term impacts on family functioning. With early diagnosis, the diagnostic process is likely to co-occur with family planning decisions, yet little is known about how parents navigate this process. This study explores family planning decision making process among mothers of young children with autism spectrum disorder in the United States, by understanding the transformation in family vision before and after the diagnosis. A total of 22 mothers of first born children, diagnosed with autism between 2 and 4 years of age, were interviewed about family vision prior to and after their child's diagnosis. Grounded Theory method was used for data analysis. Findings indicated that coherence of early family vision, maternal cognitive flexibility, and maternal responses to diagnosis were highly influential in future family planning decisions. The decision to have additional children reflected a high level of adaptability built upon a solid internalized family model and a flexible approach to life. Decision to stop childrearing reflected a relatively less coherent family model and more rigid cognitive style followed by ongoing hardship managing life after the diagnosis. This report may be useful for health-care providers in enhancing therapeutic alliance and guiding family planning counseling. © The Author(s) 2015.

Preservice Teachers' Perspective Transformations as Social Change Agents

ERIC Educational Resources Information Center

Woodrow, Kelli; Caruana, Vicki

2017-01-01

In this article, we investigate whether, and in what ways, the learning experiences in a capstone course in reflective teaching impact the perspective transformations (PT) of preservice teachers toward a diverse K-12 student population and the plans of preservice teachers to take future action as change agents. Using an adaptation of the Learning…

Transforming the structure of a health system.

PubMed

Reilly, Patrick

2012-06-01

In starting the planning process for an organization's transformation or restructuring, healthcare finance leaders should: Identify strategic imperatives for the organization and physicians, Remember the organization's core area of business, Define the starting point and create clear objectives, Develop a strategy that engages front-line employees to change the culture of the organization.

Planning for Low End Analytics Disruptions in Business School Curricula

ERIC Educational Resources Information Center

Rienzo, Thomas; Chen, Kuanchin

2018-01-01

Analytics is getting a great deal of attention in both industrial and academic venues. Organizations of all types are becoming more serious about transforming data from a variety of sources into insight, and analytics is the key to that transformation. Academic institutions are rapidly responding to the demand for analytics talent, with hundreds…

Teaching/Learning Geometric Transformations in High-School with DGS

ERIC Educational Resources Information Center

Ferrarello, Daniela; Mammana, Maria Flavia; Pennisi, Mario

2014-01-01

In this paper, we present the results of an experimental sequence of classroom activities on geometric transformations, proposed to high-school students. The activity is based on the use of a dynamic geometry system. Planned by a group of four people, two university professors and two research teachers, the activity has been elaborated together…

School and Community Wellness: Transforming Achievement Using a Holistic Orientation to Learning

ERIC Educational Resources Information Center

Oser, Rick; Beck, Ellen; Alvarado, Jose Luis; Pang, Valerie Ooka

2014-01-01

A comprehensive school and community wellness plan was developed and implemented to transform "Lemon Grove Academy" for the Sciences and Humanities, an urban school, where student achievement and faculty satisfaction has soared. The school has become the center for the local neighborhood where culture, language, and equity are valued.…

How a Museum Discovered the Transforming Power of Play

ERIC Educational Resources Information Center

Eberle, Scott G.

2008-01-01

In 2006 the Strong Museum in Rochester, New York reopened as the Strong National Museum of Play. Devising a new interpretive plan proved crucial to transforming the institution's mission and decisive in leading toward a $37 million expansion that drove strong gains in attendance. Still, the new interpretive direction, articulated in the museum's…

Transforming the Corporate Training Function through Developing a Training Strategy and Advisory Board: A Longitudinal Case Study

ERIC Educational Resources Information Center

Kalman, Howard K.

2008-01-01

This study examined use of a strategic planning process to reinvent a corporate training department. The naturalistic case describes how the corporate training function gained credibility and influence with senior management, developed alignment with organizational goals, and began transforming the function into a performance improvement…

Methods for genetic transformation of filamentous fungi.

PubMed

Li, Dandan; Tang, Yu; Lin, Jun; Cai, Weiwen

2017-10-03

Filamentous fungi have been of great interest because of their excellent ability as cell factories to manufacture useful products for human beings. The development of genetic transformation techniques is a precondition that enables scientists to target and modify genes efficiently and may reveal the function of target genes. The method to deliver foreign nucleic acid into cells is the sticking point for fungal genome modification. Up to date, there are some general methods of genetic transformation for fungi, including protoplast-mediated transformation, Agrobacterium-mediated transformation, electroporation, biolistic method and shock-wave-mediated transformation. This article reviews basic protocols and principles of these transformation methods, as well as their advantages and disadvantages.

Emerging Definition of Next-Generation of Aeronautical Communications

NASA Technical Reports Server (NTRS)

Kerczewski, Robert J.

2006-01-01

Aviation continues to experience rapid growth. In regions such as the United States and Europe air traffic congestion is constraining operations, leading to major new efforts to develop methodologies and infrastructures to enable continued aviation growth through transformational air traffic management systems. Such a transformation requires better communications linking airborne and ground-based elements. Technologies for next-generation communications, the required capacities, frequency spectrum of operation, network interconnectivity, and global interoperability are now receiving increased attention. A number of major planning and development efforts have taken place or are in process now to define the transformed airspace of the future. These activities include government and industry led efforts in the United States and Europe, and by international organizations. This paper will review the features, approaches, and activities of several representative planning and development efforts, and identify the emerging global consensus on requirements of next generation aeronautical communications systems for air traffic control.

A bottom-up approach to urban metabolism: the perspective of BRIDGE

NASA Astrophysics Data System (ADS)

Chrysoulakis, N.; Borrego, C.; San Josè, R.; Grimmond, S. B.; Jones, M. B.; Magliulo, V.; Klostermann, J.; Santamouris, M.

2011-12-01

Urban metabolism considers a city as a system and usually distinguishes between energy and material flows as its components. "Metabolic" studies are usually top-down approaches that assess the inputs and outputs of food, water, energy, and pollutants from a city, or that compare the changing metabolic process of several cities. In contrast, bottom-up approaches are based on quantitative estimates of urban metabolism components at local to regional scales. Such approaches consider the urban metabolism as the 3D exchange and transformation of energy and matter between a city and its environment. The city is considered as a system and the physical flows between this system and its environment are quantitatively estimated. The transformation of landscapes from primarily agricultural and forest uses to urbanized landscapes can greatly modify energy and material exchanges and it is, therefore, an important aspect of an urban area. Here we focus on the exchanges and transformation of energy, water, carbon and pollutants. Recent advances in bio-physical sciences have led to new methods and models to estimate local scale energy, water, carbon and pollutant fluxes. However, there is often poor communication of new knowledge and its implications to end-users, such as planners, architects and engineers. The FP7 Project BRIDGE (SustainaBle uRban plannIng Decision support accountinG for urban mEtabolism) aims at bridging this gap and at illustrating the advantages of considering environmental issues in urban planning. BRIDGE does not perform a complete life cycle analysis or calculate whole system urban metabolism, but rather focuses on specific metabolism components (energy, water, carbon and pollutants). Its main goal is the development of a Decision Suport System (DSS) with the potential to select planning actions which better fit the goal of changing the metabolism of urban systems towards sustainability. BRIDGE evaluates how planning alternatives can modify the physical flows of the above urban metabolism components under consideration in five European cities: Helsinki, Athens, London, Firenze and Gliwice. A Multi-Criteria Evaluation approach has been adopted. To cope with the complexity of urban metabolism issues, objectives are defined in relation to the interactions between the environmental elements (fluxes of energy, water, carbon and pollutants) and socio-economic components (investment costs, housing, employment, etc.) of urban sustainability.

The Virginia pharmacy practice transformation conference: outcomes and next steps.

PubMed

Silvester, Janet A

2012-04-01

Thought leaders in Virginia came together to achieve consensus on the pharmacy practice innovations required to advance the medication-related health outcomes of patients in the Commonwealth. The participants identified key elements and strategies needed for practice transformation and these became the foundation for practice change. The primary key elements included legislation and regulation modifications, payment reform, and business model development. The Virginia Pharmacy Congress, which represents key pharmacy stakeholders in the Commonwealth, became the home for the transformation movement and the development and implementation of a unified action plan for achieving the envisioned practice transformation.

Healthcare @ The Speed of Thought: A digital world needs successful transformative leaders.

PubMed

Tremblay, Ken

2017-09-01

In the wake of transformational change powered by the digital era, resultant leadership challenges and strategies essential for successful change, both tactical and cultural, are linked to defined capabilities within the Systems Transformation domain of the LEADS in a Caring Environment framework. Honed from experience, specific softer leadership behaviours supporting system transformation are both described and reinforced. Further, a matrix combining the LEADS framework capabilities with these more specific behaviours is offered as a planning tool that leaders may reflect upon and map out key activities associated with their sponsorship of significant change.

Modelling and Experiment Based on a Navigation System for a Cranio-Maxillofacial Surgical Robot.

PubMed

Duan, Xingguang; Gao, Liang; Wang, Yonggui; Li, Jianxi; Li, Haoyuan; Guo, Yanjun

2018-01-01

In view of the characteristics of high risk and high accuracy in cranio-maxillofacial surgery, we present a novel surgical robot system that can be used in a variety of surgeries. The surgical robot system can assist surgeons in completing biopsy of skull base lesions, radiofrequency thermocoagulation of the trigeminal ganglion, and radioactive particle implantation of skull base malignant tumors. This paper focuses on modelling and experimental analyses of the robot system based on navigation technology. Firstly, the transformation relationship between the subsystems is realized based on the quaternion and the iterative closest point registration algorithm. The hand-eye coordination model based on optical navigation is established to control the end effector of the robot moving to the target position along the planning path. The closed-loop control method, "kinematics + optics" hybrid motion control method, is presented to improve the positioning accuracy of the system. Secondly, the accuracy of the system model was tested by model experiments. And the feasibility of the closed-loop control method was verified by comparing the positioning accuracy before and after the application of the method. Finally, the skull model experiments were performed to evaluate the function of the surgical robot system. The results validate its feasibility and are consistent with the preoperative surgical planning.

Modelling and Experiment Based on a Navigation System for a Cranio-Maxillofacial Surgical Robot

PubMed Central

Duan, Xingguang; Gao, Liang; Li, Jianxi; Li, Haoyuan; Guo, Yanjun

2018-01-01

In view of the characteristics of high risk and high accuracy in cranio-maxillofacial surgery, we present a novel surgical robot system that can be used in a variety of surgeries. The surgical robot system can assist surgeons in completing biopsy of skull base lesions, radiofrequency thermocoagulation of the trigeminal ganglion, and radioactive particle implantation of skull base malignant tumors. This paper focuses on modelling and experimental analyses of the robot system based on navigation technology. Firstly, the transformation relationship between the subsystems is realized based on the quaternion and the iterative closest point registration algorithm. The hand-eye coordination model based on optical navigation is established to control the end effector of the robot moving to the target position along the planning path. The closed-loop control method, “kinematics + optics” hybrid motion control method, is presented to improve the positioning accuracy of the system. Secondly, the accuracy of the system model was tested by model experiments. And the feasibility of the closed-loop control method was verified by comparing the positioning accuracy before and after the application of the method. Finally, the skull model experiments were performed to evaluate the function of the surgical robot system. The results validate its feasibility and are consistent with the preoperative surgical planning. PMID:29599948

A rapid, highly efficient and economical method of Agrobacterium-mediated in planta transient transformation in living onion epidermis.

PubMed

Xu, Kedong; Huang, Xiaohui; Wu, Manman; Wang, Yan; Chang, Yunxia; Liu, Kun; Zhang, Ju; Zhang, Yi; Zhang, Fuli; Yi, Liming; Li, Tingting; Wang, Ruiyue; Tan, Guangxuan; Li, Chengwei

2014-01-01

Transient transformation is simpler, more efficient and economical in analyzing protein subcellular localization than stable transformation. Fluorescent fusion proteins were often used in transient transformation to follow the in vivo behavior of proteins. Onion epidermis, which has large, living and transparent cells in a monolayer, is suitable to visualize fluorescent fusion proteins. The often used transient transformation methods included particle bombardment, protoplast transfection and Agrobacterium-mediated transformation. Particle bombardment in onion epidermis was successfully established, however, it was expensive, biolistic equipment dependent and with low transformation efficiency. We developed a highly efficient in planta transient transformation method in onion epidermis by using a special agroinfiltration method, which could be fulfilled within 5 days from the pretreatment of onion bulb to the best time-point for analyzing gene expression. The transformation conditions were optimized to achieve 43.87% transformation efficiency in living onion epidermis. The developed method has advantages in cost, time-consuming, equipment dependency and transformation efficiency in contrast with those methods of particle bombardment in onion epidermal cells, protoplast transfection and Agrobacterium-mediated transient transformation in leaf epidermal cells of other plants. It will facilitate the analysis of protein subcellular localization on a large scale.

The Transformation of a College.

ERIC Educational Resources Information Center

Wisniewski, Richard

1996-01-01

Describes the restructuring process at the University of Tennessee, Knoxville, focusing on changes in the College of Education over four years. Grant monies allowed faculty members to attend programs and conferences, hire specialists, develop a planning document, implement a plan that included 11 new units, and elect unit leaders. (SM)

Transforming data into information : the development and demonstration of a model to support transportation planning.

DOT National Transportation Integrated Search

2005-04-01

A previous study of information systems at the Division of Planning at the Delaware : Department of Transportation (DelDOT) was conducted in response to concerns about : data management issues and what could be done to improve information systems. So...

Collection and analysis of high-resolution elevation data for the Lincoln Lidar Project, Lincoln, Nebraska, 2004

USGS Publications Warehouse

Meyer, P.D.; Greenlee, Susan K.; Gesch, Dean B.; Hubl, Erik J.; Axmann, Ryan N.

2005-01-01

The Lincoln Lidar Project was a partnership developed between the U.S. Geological Survey National Center for Earth Resources Observations and Science (EROS), Lancaster County and the city of Lincoln, Nebraska. This project demonstrated a successful planning, collection, analysis and integration of high-resolution elevation information using Light Detection and Ranging, (Lidar) data. This report describes the partnership developed to collect local Lidar data and transform the data into information useable at local to national levels. This report specifically describes project planning, quality assurance, processing, transforming raw Lidar points to useable data layers, and visualizing and disseminating the raw and final products.

Water Fountains in Environment Transformation Correcting

NASA Astrophysics Data System (ADS)

Sidorenko, M. Yu; Ponomareva, Zh V.

2017-11-01

The article provides information on the means and principles for adjusting the process of the urban environment transformation. The interest in the topic is caused by the fact that the surrounding artificial environment is turning into a dangerous factor in the mechanism of human visual perception which requires immediate, effective intervention in the adjustment of the existing modern buildings. The paper considers The correction with the help of new dominants, small architectural forms, in particular, water fountains. Fountains are an important part of the measures to create a comfortable, environmentally friendly urban human environment. Their planning and functional links with the system of streets, squares, traffic arteries can create the urban plan basis.

A Quality Assurance Method that Utilizes 3D Dosimetry and Facilitates Clinical Interpretation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oldham, Mark, E-mail: mark.oldham@duke.edu; Thomas, Andrew; O'Daniel, Jennifer

2012-10-01

Purpose: To demonstrate a new three-dimensional (3D) quality assurance (QA) method that provides comprehensive dosimetry verification and facilitates evaluation of the clinical significance of QA data acquired in a phantom. Also to apply the method to investigate the dosimetric efficacy of base-of-skull (BOS) intensity-modulated radiotherapy (IMRT) treatment. Methods and Materials: Two types of IMRT QA verification plans were created for 6 patients who received BOS IMRT. The first plan enabled conventional 2D planar IMRT QA using the Varian portal dosimetry system. The second plan enabled 3D verification using an anthropomorphic head phantom. In the latter, the 3D dose distribution wasmore » measured using the DLOS/Presage dosimetry system (DLOS = Duke Large-field-of-view Optical-CT System, Presage Heuris Pharma, Skillman, NJ), which yielded isotropic 2-mm data throughout the treated volume. In a novel step, measured 3D dose distributions were transformed back to the patient's CT to enable calculation of dose-volume histograms (DVH) and dose overlays. Measured and planned patient DVHs were compared to investigate clinical significance. Results: Close agreement between measured and calculated dose distributions was observed for all 6 cases. For gamma criteria of 3%, 2 mm, the mean passing rate for portal dosimetry was 96.8% (range, 92.0%-98.9%), compared to 94.9% (range, 90.1%-98.9%) for 3D. There was no clear correlation between 2D and 3D passing rates. Planned and measured dose distributions were evaluated on the patient's anatomy, using DVH and dose overlays. Minor deviations were detected, and the clinical significance of these are presented and discussed. Conclusions: Two advantages accrue to the methods presented here. First, treatment accuracy is evaluated throughout the whole treated volume, yielding comprehensive verification. Second, the clinical significance of any deviations can be assessed through the generation of DVH curves and dose overlays on the patient's anatomy. The latter step represents an important development that advances the clinical relevance of complex treatment QA.« less

Toward perception-based navigation using EgoSphere

NASA Astrophysics Data System (ADS)

Kawamura, Kazuhiko; Peters, R. Alan; Wilkes, Don M.; Koku, Ahmet B.; Sekman, Ali

2002-02-01

A method for perception-based egocentric navigation of mobile robots is described. Each robot has a local short-term memory structure called the Sensory EgoSphere (SES), which is indexed by azimuth, elevation, and time. Directional sensory processing modules write information on the SES at the location corresponding to the source direction. Each robot has a partial map of its operational area that it has received a priori. The map is populated with landmarks and is not necessarily metrically accurate. Each robot is given a goal location and a route plan. The route plan is a set of via-points that are not used directly. Instead, a robot uses each point to construct a Landmark EgoSphere (LES) a circular projection of the landmarks from the map onto an EgoSphere centered at the via-point. Under normal circumstances, the LES will be mostly unaffected by slight variations in the via-point location. Thus, the route plan is transformed into a set of via-regions each described by an LES. A robot navigates by comparing the next LES in its route plan to the current contents of its SES. It heads toward the indicated landmarks until its SES matches the LES sufficiently to indicate that the robot is near the suggested via-point. The proposed method is particularly useful for enabling the exchange of robust route informa-tion between robots under low data rate communications constraints. An example of such an exchange is given.

Global temperature patterns 6000 years ago. Progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Webb, T. III

The overall goal is to illustrate the climatic patterns of 5000 to 7000 years ago over as wide an area of the northern hemisphere as possible. Mapping of the patterns in selected climatic variables at 5000 to 7000 years ago that can be reconstructed from pollen and marine-plankton data is planned. Multivariate statistical methods permit using the modern distribution of these data in order to transform their fossil remains into climate estimates of past times. Given these goals and methods, research during the first eight months focused on assembling the available modern and fossil data from each of the mainmore » areas under study. Two workshop conferences were held to help organize the joint work.« less

Searching for Innovations and Methods of Using the Cultural Heritage on the Example of Upper Silesia

NASA Astrophysics Data System (ADS)

Wagner, Tomasz

2017-10-01

The basic subject of this paper is historical and cultural heritage of some parts of Upper Silesia, bind by common history and similar problems at present days. The paper presents some selected historical phenomena that have influenced contemporary space, mentioned above, and contemporary issues of heritage protection in Upper Silesia. The Silesian architecture interpretation, since 1989, is strongly covered with some ideological and national ideas. The last 25 years are the next level of development which contains rapidly transformation of the space what is caused by another economical transformations. In this period, we can observe landscape transformations, liquidation of objects and historical structures, loos of regional features, spontaneous adaptation processes of objects and many methods of implementation forms of protection, and using of cultural resources. Some upheaval linked to the state borders changes, system, economy and ethnic transformation caused that former Upper Silesia border area focuses phenomena that exists in some other similar European areas which are abutments of cultures and traditions. The latest period in the history of Upper Silesia gives us time to reflect the character of changes in architecture and city planning of the area and appraisal of efficiency these practices which are connected to cultural heritage perseveration. The phenomena of the last decades are: decrement of regional features, elimination of objects, which were a key feature of the regional cultural heritage, deformation of these forms that were shaped in the history and some trials of using these elements of cultural heritage, which are widely recognized as cultural values. In this situation, it is important to seek creative solutions that will neutralize bad processes resulting from bad law and practice. The most important phenomena of temporary space is searching of innovative fields and methods and use of cultural resources. An important part of the article is the role of the ‘network community’ in the protection of cultural heritage.

A novel method for accurate needle-tip identification in trans-rectal ultrasound-based high-dose-rate prostate brachytherapy.

PubMed

Zheng, Dandan; Todor, Dorin A

2011-01-01

In real-time trans-rectal ultrasound (TRUS)-based high-dose-rate prostate brachytherapy, the accurate identification of needle-tip position is critical for treatment planning and delivery. Currently, needle-tip identification on ultrasound images can be subject to large uncertainty and errors because of ultrasound image quality and imaging artifacts. To address this problem, we developed a method based on physical measurements with simple and practical implementation to improve the accuracy and robustness of needle-tip identification. Our method uses measurements of the residual needle length and an off-line pre-established coordinate transformation factor, to calculate the needle-tip position on the TRUS images. The transformation factor was established through a one-time systematic set of measurements of the probe and template holder positions, applicable to all patients. To compare the accuracy and robustness of the proposed method and the conventional method (ultrasound detection), based on the gold-standard X-ray fluoroscopy, extensive measurements were conducted in water and gel phantoms. In water phantom, our method showed an average tip-detection accuracy of 0.7 mm compared with 1.6 mm of the conventional method. In gel phantom (more realistic and tissue-like), our method maintained its level of accuracy while the uncertainty of the conventional method was 3.4mm on average with maximum values of over 10mm because of imaging artifacts. A novel method based on simple physical measurements was developed to accurately detect the needle-tip position for TRUS-based high-dose-rate prostate brachytherapy. The method demonstrated much improved accuracy and robustness over the conventional method. Copyright © 2011 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.

Gait biomechanics in the era of data science.

PubMed

Ferber, Reed; Osis, Sean T; Hicks, Jennifer L; Delp, Scott L

2016-12-08

Data science has transformed fields such as computer vision and economics. The ability of modern data science methods to extract insights from large, complex, heterogeneous, and noisy datasets is beginning to provide a powerful complement to the traditional approaches of experimental motion capture and biomechanical modeling. The purpose of this article is to provide a perspective on how data science methods can be incorporated into our field to advance our understanding of gait biomechanics and improve treatment planning procedures. We provide examples of how data science approaches have been applied to biomechanical data. We then discuss the challenges that remain for effectively using data science approaches in clinical gait analysis and gait biomechanics research, including the need for new tools, better infrastructure and incentives for sharing data, and education across the disciplines of biomechanics and data science. By addressing these challenges, we can revolutionize treatment planning and biomechanics research by capitalizing on the wealth of knowledge gained by gait researchers over the past decades and the vast, but often siloed, data that are collected in clinical and research laboratories around the world. Copyright © 2016 Elsevier Ltd. All rights reserved.

Box-Cox transformation for QTL mapping.

PubMed

Yang, Runqing; Yi, Nengjun; Xu, Shizhong

2006-01-01

The maximum likelihood method of QTL mapping assumes that the phenotypic values of a quantitative trait follow a normal distribution. If the assumption is violated, some forms of transformation should be taken to make the assumption approximately true. The Box-Cox transformation is a general transformation method which can be applied to many different types of data. The flexibility of the Box-Cox transformation is due to a variable, called transformation factor, appearing in the Box-Cox formula. We developed a maximum likelihood method that treats the transformation factor as an unknown parameter, which is estimated from the data simultaneously along with the QTL parameters. The method makes an objective choice of data transformation and thus can be applied to QTL analysis for many different types of data. Simulation studies show that (1) Box-Cox transformation can substantially increase the power of QTL detection; (2) Box-Cox transformation can replace some specialized transformation methods that are commonly used in QTL mapping; and (3) applying the Box-Cox transformation to data already normally distributed does not harm the result.

Regional landslide-hazard assessment for Seattle, Washington, USA

USGS Publications Warehouse

Baum, R.L.; Coe, J.A.; Godt, J.W.; Harp, E.L.; Reid, M.E.; Savage, W.Z.; Schulz, W.H.; Brien, D.L.; Chleborad, A.F.; McKenna, J.P.; Michael, J.A.

2005-01-01

Landslides are a widespread, frequent, and costly hazard in Seattle and the Puget Sound area of Washington State, USA. Shallow earth slides triggered by heavy rainfall are the most common type of landslide in the area; many transform into debris flows and cause significant property damage or disrupt transportation. Large rotational and translational slides, though less common, also cause serious property damage. The hundreds of landslides that occurred during the winters of 1995-96 and 1996-97 stimulated renewed interest by Puget Sound communities in identifying landslide-prone areas and taking actions to reduce future landslide losses. Informal partnerships between the U.S. Geological Survey (USGS), the City of Seattle, and private consultants are focusing on the problem of identifying and mapping areas of landslide hazard as well as characterizing temporal aspects of the hazard. We have developed GIS-based methods to map the probability of landslide occurrence as well as empirical rainfall thresholds and physically based methods to forecast times of landslide occurrence. Our methods for mapping landslide hazard zones began with field studies and physically based models to assess relative slope stability, including the effects of material properties, seasonal groundwater levels, and rainfall infiltration. We have analyzed the correlation between historic landslide occurrence and relative slope stability to map the degree of landslide hazard. The City of Seattle is using results of the USGS studies in storm preparedness planning for emergency access and response, planning for development or redevelopment of hillsides, and municipal facility planning and prioritization. Methods we have developed could be applied elsewhere to suit local needs and available data.

O

NASA Astrophysics Data System (ADS)

Donnellan, Karen

My work is driven by the metaphysical and the potential for healing through the manipulation of energy. Points of research include the enso (the only symbol used in Zen Buddhism), which uses the circle as a symbol of wholeness, divinity, and enlightenment. The writings of Alex Grey, Eckhart Tolle and the work of Ann Hamilton will also be investigated. I plan to create work from turned wooden vortex forms, the shapes of which are based on the movement of energy within the body. These objects will be transformed from wood, through rubber, wax, plaster, iron, bronze to cast, and blown glass. This transformation through materials is becoming a metaphor for the continuous transformation of universal light and energy. As part of my material research, I will exploit various casting techniques including kiln casting, hot casting, and pate de verre. Photography, film, and projection also will be explored. Conceptually, the process will become an integral part of the work where involved, repetitive methods will be treated as a meditation or mantra and will, in turn, add a performative dimension to the work. It is through these meditative practices that I intend to imbue the work with healing energies.

[Family planning at the turn of the 21st century].

PubMed

Trias, M

1994-06-01

This work constitutes a plea for the widest possible acceptance and encouragement of family planning throughout the world in order to avoid the irreversible environmental damage that will inevitably come with excessive numbers. Limitation of reproduction, preferably voluntarily, is possible by means of the effective and generally safe contraceptive methods now available. Preservation of the environment will require effective antipollution policies and an unwelcome control of the rampant consumerism of contemporary culture. Alarm among demographers in developed countries concerning exponential population increase developed about a half-century ago, only shortly after the feminist-led struggle for reproductive freedom provided a moral and juridical foundation for family planning. The demographic focus was not used to promote family planning among Third World countries, as that would have been viewed as heavy handed intrusion into the most intimate realm of domestic life. Instead, the nondemographic benefits such as improved maternal and child health and family well-being were stressed. It may be time to modify the focus. Ecologists must strive for a radical transformation of consumerist culture but must not ignore the pressure of numbers. Satisfying the needs of the world's most impoverished will greatly increase pressure on resources. Family planning has been accepted by the majority of the world's couples, but the unsatisfied demand has been estimated to amount to 100 million couples throughout the world. Providing information and services for such couples is the greatest challenge facing family planning programs. Many enemies of family planning have lost influence, but some critics from within family planning programs have deflected attention from the tasks of service delivery and may have postponed progress in some areas. Feminists who object to the concentration on female methods, developmentalists who believe that contraception will be accepted eventually as living standards improve, and integrationists who emphasize maternal-child health services to the detriment of family planning are examples. In view of the environmental threat as the twenty-first century dawns, the time may have come to view family planning not only as a right, but as a duty.

Patient care transformation: the plan and the reality.

PubMed

Drexler, Diane; Malloch, Kathy

2006-01-01

An explosion of new hospital building has created the opportunity for nurse leaders to transform the patient care experience with evidence-based architecture, technology innovations, and new patient care delivery models. The authors share the first-year results of the creation of a hospital of the future in which staff actively participated and addressed the challenges of transforming the patient care experience. Positive results include patient satisfaction at the 99th percentile, successful integration of 63 software applications, and energized nursing staff.

A Unified Method of Finding Laplace Transforms, Fourier Transforms, and Fourier Series. [and] An Inversion Method for Laplace Transforms, Fourier Transforms, and Fourier Series. Integral Transforms and Series Expansions. Modules and Monographs in Undergraduate Mathematics and Its Applications Project. UMAP Units 324 and 325.

ERIC Educational Resources Information Center

Grimm, C. A.

This document contains two units that examine integral transforms and series expansions. In the first module, the user is expected to learn how to use the unified method presented to obtain Laplace transforms, Fourier transforms, complex Fourier series, real Fourier series, and half-range sine series for given piecewise continuous functions. In…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Katsuta, Y; Tohoku University Graduate School of Medicine, Sendal, Miyagi; Kadoya, N

Purpose: In this study, we developed a system to calculate three dimensional (3D) dose that reflects dosimetric error caused by leaf miscalibration for head and neck and prostate volumetric modulated arc therapy (VMAT) without additional treatment planning system calculation on real time. Methods: An original system called clarkson dose calculation based dosimetric error calculation to calculate dosimetric error caused by leaf miscalibration was developed by MATLAB (Math Works, Natick, MA). Our program, first, calculates point doses at isocenter for baseline and modified VMAT plan, which generated by inducing MLC errors that enlarged aperture size of 1.0 mm with clarkson dosemore » calculation. Second, error incuced 3D dose was generated with transforming TPS baseline 3D dose using calculated point doses. Results: Mean computing time was less than 5 seconds. For seven head and neck and prostate plans, between our method and TPS calculated error incuced 3D dose, the 3D gamma passing rates (0.5%/2 mm, global) are 97.6±0.6% and 98.0±0.4%. The dose percentage change with dose volume histogram parameter of mean dose on target volume were 0.1±0.5% and 0.4±0.3%, and with generalized equivalent uniform dose on target volume were −0.2±0.5% and 0.2±0.3%. Conclusion: The erroneous 3D dose calculated by our method is useful to check dosimetric error caused by leaf miscalibration before pre treatment patient QA dosimetry checks.« less

Revenue Forecasting to Integrate CCC Planning and Resource Allocation for Transformative Leadership

ERIC Educational Resources Information Center

Hovey, Ann

2012-01-01

In recent years the majority of California community colleges evaluated for re-accreditation received sanctions requiring documented improvement in the integration of college planning and budgeting processes. This study explores the challenges colleges face and the best practices utilized by successful colleges in implementing integrated…

7 CFR 1724.54 - Requirements for RUS approval of plans and specifications.

Code of Federal Regulations, 2011 CFR

2011-01-01

... specifications for transmission construction projects which are not based on RUS approved line design data or do... section, plans and specifications for transmission construction which use previously approved design data... transformer, and the transmission switchyard at a generating plant. Warehouses and equipment service buildings...

Planning chemical syntheses with deep neural networks and symbolic AI

NASA Astrophysics Data System (ADS)

Segler, Marwin H. S.; Preuss, Mike; Waller, Mark P.

2018-03-01

To plan the syntheses of small organic molecules, chemists use retrosynthesis, a problem-solving technique in which target molecules are recursively transformed into increasingly simpler precursors. Computer-aided retrosynthesis would be a valuable tool but at present it is slow and provides results of unsatisfactory quality. Here we use Monte Carlo tree search and symbolic artificial intelligence (AI) to discover retrosynthetic routes. We combined Monte Carlo tree search with an expansion policy network that guides the search, and a filter network to pre-select the most promising retrosynthetic steps. These deep neural networks were trained on essentially all reactions ever published in organic chemistry. Our system solves for almost twice as many molecules, thirty times faster than the traditional computer-aided search method, which is based on extracted rules and hand-designed heuristics. In a double-blind AB test, chemists on average considered our computer-generated routes to be equivalent to reported literature routes.

National Agenda: A Holistic Approach towards Development of the Campus Improvement Plan Using "Ways of Knowing through the Realms of Meaning" as the Framework

ERIC Educational Resources Information Center

Cloud, Michelle; Kritsonis, William Allan

2006-01-01

This article seeks to examine "Ways of Knowing Through the Realms of Meaning" (2007) by Dr. William Allan Kritsonis as a framework that transformational educational leaders can use to guide members of the Site Based Decision Making Team through development of the Campus Improvement Plan. The Campus Improvement Plan serves as a blueprint for…

A Rapid, Highly Efficient and Economical Method of Agrobacterium-Mediated In planta Transient Transformation in Living Onion Epidermis

PubMed Central

Xu, Kedong; Huang, Xiaohui; Wu, Manman; Wang, Yan; Chang, Yunxia; Liu, Kun; Zhang, Ju; Zhang, Yi; Zhang, Fuli; Yi, Liming; Li, Tingting; Wang, Ruiyue; Tan, Guangxuan; Li, Chengwei

2014-01-01

Transient transformation is simpler, more efficient and economical in analyzing protein subcellular localization than stable transformation. Fluorescent fusion proteins were often used in transient transformation to follow the in vivo behavior of proteins. Onion epidermis, which has large, living and transparent cells in a monolayer, is suitable to visualize fluorescent fusion proteins. The often used transient transformation methods included particle bombardment, protoplast transfection and Agrobacterium-mediated transformation. Particle bombardment in onion epidermis was successfully established, however, it was expensive, biolistic equipment dependent and with low transformation efficiency. We developed a highly efficient in planta transient transformation method in onion epidermis by using a special agroinfiltration method, which could be fulfilled within 5 days from the pretreatment of onion bulb to the best time-point for analyzing gene expression. The transformation conditions were optimized to achieve 43.87% transformation efficiency in living onion epidermis. The developed method has advantages in cost, time-consuming, equipment dependency and transformation efficiency in contrast with those methods of particle bombardment in onion epidermal cells, protoplast transfection and Agrobacterium-mediated transient transformation in leaf epidermal cells of other plants. It will facilitate the analysis of protein subcellular localization on a large scale. PMID:24416168

How Colleges Use Integrated Planning and Advising for Student Success (iPASS) to Transform Student Support. CCRC Working Paper No. 89

ERIC Educational Resources Information Center

Karp, Melinda Mechur; Kalamkarian, Hoori Santikian; Klempin, Serena; Fletcher, Jeffrey

2016-01-01

This paper examines technology-mediated advising reform in order to contribute to the understanding of how colleges engage in transformative change to improve student outcomes. Conceptualizing such change as occurring along three interrelated dimensions of organizational functioning (structural, process, and attitudinal), we seek to understand the…

Using Technology and Innovation for Planning Social and Economic Transformation in a Region of Mexico

ERIC Educational Resources Information Center

Villanueva, Gonzalo Rodriguez; Lagarda Leyva, Ernesto A.

2009-01-01

This article shows the possibility of achieving social transformation by applying the triple helix model, which establishes the university's participation and its research centers, the government and its three levels, and the private sector (Etzkowitz, 2002). These three allies have shared the vision and participated during the entire process,…

The Relationship between Chief Information Officer Transformational Leadership and Computing Platform Operating Systems

ERIC Educational Resources Information Center

Anderson, George W.

2010-01-01

The purpose of this study was to relate the strength of Chief Information Officer (CIO) transformational leadership behaviors to 1 of 5 computing platform operating systems (OSs) that may be selected for a firm's Enterprise Resource Planning (ERP) business system. Research shows executive leader behaviors may promote innovation through the use of…

An Exploration of Transformational Leadership and Its Role in Strategic Planning: A Conceptual Framework.

ERIC Educational Resources Information Center

Turan, Selahattin; Sny, Christopher L.

The literature on transformational leadership is reviewed to provide a theoretical framework for leaders in educational organizations. Our rapidly changing society calls for a new type of educational leadership. Drawing on the work of J. M. Burns (1978) and B. M. Bass (1985) among others, transactional leaders are distinguished from…

Transforming Knowledge in Undergraduate Teacher Education. A Craft Paper 91-1.

ERIC Educational Resources Information Center

Reid, Gem

This paper examines the teacher educator's role in assisting prospective teachers to grasp what it means to transform knowledge so that content and pedagogy intersect. Knowledge is not certain nor is its authority held in the text or the teacher's lesson plans. If students perceive knowledge to be open-ended, requiring vital curiosity, they will…

Complementary Expertise in a Zoo Educator Professional Development Event Contributes to the Construction of Understandings of Affective Transformation

ERIC Educational Resources Information Center

Kelly, Lisa-Anne DeGregoria; Kassing, Sharon

2013-01-01

Cultural Historical Activity Theory served as the analytical framework for the study of a professional development event for a zoo's education department, specifically designed to build understandings of "Affective Transformation," an element pertinent to the organization's strategic plan. Three key products--an Affective…

Towards a Strength-Based Juvenile Correctional Facility: Sustainability and Effects of an Institutional Transformation

ERIC Educational Resources Information Center

Barton, William H.; Mackin, Juliette R.

2012-01-01

In 2006, the administration of a state-run, secure juvenile correctional facility initiated an attempt to transform its institutional culture using a strength-based approach to assessment and case planning. This resulted in a rapid improvement in institutional climate. The current study revisits this setting several years later to see if those…

Combination of oriented partial differential equation and shearlet transform for denoising in electronic speckle pattern interferometry fringe patterns.

PubMed

Xu, Wenjun; Tang, Chen; Gu, Fan; Cheng, Jiajia

2017-04-01

It is a key step to remove the massive speckle noise in electronic speckle pattern interferometry (ESPI) fringe patterns. In the spatial-domain filtering methods, oriented partial differential equations have been demonstrated to be a powerful tool. In the transform-domain filtering methods, the shearlet transform is a state-of-the-art method. In this paper, we propose a filtering method for ESPI fringe patterns denoising, which is a combination of second-order oriented partial differential equation (SOOPDE) and the shearlet transform, named SOOPDE-Shearlet. Here, the shearlet transform is introduced into the ESPI fringe patterns denoising for the first time. This combination takes advantage of the fact that the spatial-domain filtering method SOOPDE and the transform-domain filtering method shearlet transform benefit from each other. We test the proposed SOOPDE-Shearlet on five experimentally obtained ESPI fringe patterns with poor quality and compare our method with SOOPDE, shearlet transform, windowed Fourier filtering (WFF), and coherence-enhancing diffusion (CEDPDE). Among them, WFF and CEDPDE are the state-of-the-art methods for ESPI fringe patterns denoising in transform domain and spatial domain, respectively. The experimental results have demonstrated the good performance of the proposed SOOPDE-Shearlet.

Transformational leadership and shared governance: an action study.

PubMed

Bamford-Wade, Anita; Moss, Cheryle

2010-10-01

The present study demonstrates the practical relevance of the concepts of transformational leadership as a Director of Nursing working with structure (shared governance) and active processes, informed by action research, to achieve the incremental breakthroughs associated with culture change in nursing. Responding to the context of a decade of health reforms in a New Zealand tertiary hospital, the leadership challenge, as a Director of Nursing, was to find ways of transforming the nursing workforce. How could nursing evolve from a relatively disempowered position within the organization (impact of the reforms) and reshape to achieve effectiveness within the new organizational culture? Interwoven with transformational leadership are action processes progressively moving forward through cycles of reconnaissance, planning, implementation and evaluation. The principles of shared governance 'partnership', 'equity', 'accountability' and 'ownership' underpin and work synchronically with the active processes in advancing the effectiveness of nursing. It is leadership for and in action. This study is descriptive and exploratory overall, and more specifically it uses reflective practice and self-reporting as methods. The outcomes of transformational leadership are evident in a confident, competent and committed nursing workforce which embraces continuous learning and expresses a professional respect for each other. The practical inter-weaving of the concepts of transformational leadership, shared governance and action processes provide a framework for sustainable change processes both at a unit and organizational level. It is the interplay between the three concepts that generates a process of creative innovation, questioning and challenging existing structures to try and reach a new level of excellence through the participation and valuing of nurses and nursing practice. © 2010 The Authors. Journal compilation © 2010 Blackwell Publishing Ltd.

Problem Solving in a Middle School Robotics Design Classroom

NASA Astrophysics Data System (ADS)

Norton, Stephen J.; McRobbie, Campbell J.; Ginns, Ian S.

2007-07-01

Little research has been conducted on how students work when they are required to plan, build and evaluate artefacts in technology rich learning environments such as those supported by tools including flow charts, Labview programming and Lego construction. In this study, activity theory was used as an analytic tool to examine the social construction of meaning. There was a focus on the effect of teachers’ goals and the rules they enacted upon student use of the flow chart planning tool, and the tools of the programming language Labview and Lego construction. It was found that the articulation of a teacher’s goals via rules and divisions of labour helped to form distinct communities of learning and influenced the development of different problem solving strategies. The use of the planning tool flow charting was associated with continuity of approach, integration of problem solutions including appreciation of the nexus between construction and programming, and greater educational transformation. Students who flow charted defined problems in a more holistic way and demonstrated more methodical, insightful and integrated approaches to their use of tools. The findings have implications for teaching in design dominated learning environments.

"If at first you don't succeed": using failure to improve teaching.

PubMed

Pinsky, L E; Irby, D M

1997-11-01

The authors surveyed a group of distinguished clinical teachers regarding episodes of failure that had subsequently led to improvements in their teaching. Specifically, they examined how these teachers had used reflection on failed approaches as a tool for experiential learning. The respondents believed that failures were as important as successes in learning to be a good teacher. Using qualitative content analysis of the respondents' comments, the authors identified eight common types of failure associated with each of the three phases of teaching: planning, teaching, and reflection. Common failures associated with the planning stage were misjudging learners, lack of preparation, presenting too much content, lack of purpose, and difficulties with audiovisuals. The primary failure associated with actual teaching was inflexibly using a single teaching method. In the reflection phase, respondents said they most often realized that they had made one of two common errors: selecting the wrong teaching strategy or incorrectly implementing a sound strategy. For each identified failure, the respondents made recommendations for improvement. The deliberative process that had guided planning, teaching, and reflecting had helped all of them transform past failures into successes.

Dynamic Loading of Substation Distribution Transformers: An Application for use in a Production Grade Environment

NASA Astrophysics Data System (ADS)

Zhang, Ming

Recent trends in the electric power industry have led to more attention to optimal operation of power transformers. In a deregulated environment, optimal operation means minimizing the maintenance and extending the life of this critical and costly equipment for the purpose of maximizing profits. Optimal utilization of a transformer can be achieved through the use of dynamic loading. A benefit of dynamic loading is that it allows better utilization of the transformer capacity, thus increasing the flexibility and reliability of the power system. This document presents the progress on a software application which can estimate the maximum time-varying loading capability of transformers. This information can be used to load devices closer to their limits without exceeding the manufacturer specified operating limits. The maximally efficient dynamic loading of transformers requires a model that can accurately predict both top-oil temperatures (TOTs) and hottest-spot temperatures (HSTs). In the previous work, two kinds of thermal TOT and HST models have been studied and used in the application: the IEEE TOT/HST models and the ASU TOT/HST models. And, several metrics have been applied to evaluate the model acceptability and determine the most appropriate models for using in the dynamic loading calculations. In this work, an investigation to improve the existing transformer thermal models performance is presented. Some factors that may affect the model performance such as improper fan status and the error caused by the poor performance of IEEE models are discussed. Additional methods to determine the reliability of transformer thermal models using metrics such as time constant and the model parameters are also provided. A new production grade application for real-time dynamic loading operating purpose is introduced. This application is developed by using an existing planning application, TTeMP, as a start point, which is designed for the dispatchers and load specialists. To overcome the limitations of TTeMP, the new application can perform dynamic loading under emergency conditions, such as loss-of transformer loading. It also has the capability to determine the emergency rating of the transformers for a real-time estimation.

Determination of design and operation parameters for upper atmospheric research instrumentation to yield optimum resolution with deconvolution. Appendix 7. [Transform Domain Skiprope Observer for tethered satellites

NASA Technical Reports Server (NTRS)

Ioup, George E.; Ioup, Juliette W.

1993-01-01

Because of the interesting science which can be performed using a satellite attached by a very long tether to a mother vehicle in orbit, such as the Space Shuttle, NASA will deploy TSS-1 (Tethered Satellite System) in 1992. A very long tether (20 km in this case) has the possibility of undergoing oscillations of several different types, or modes, and higher harmonics of these modes. The purpose of this document is to describe a method for detecting the amplitude, frequency, and phase (and predicting future motion in the steady state) of these modes, in particular, the skiprope mode, using tethered satellite dynamics measurements. Specifically the rotation rate data about two orthogonal axes, calculated from output from satellite gyroscopes, are used. The data of interest are the satellite pitch and roll rate measurements. NASA has determined to use two methods to diagnose skiprope properties and predict future values. One of these, a Fourier transform domain approach, is the subject of this notebook. The main program and all subroutines are described along with the test plan for evaluating the Frequency Domain Skiprope Observer.

STEM Career Changers' Transformation into Science Teachers

NASA Astrophysics Data System (ADS)

Snyder, Catherine; Oliveira, Alandeom W.; Paska, Lawrence M.

2013-06-01

This study examines the transformation (professional growth) of career-changing women scientists who decided to become teachers. Drawing upon Mezirow's Transformative Learning Theory, we tracked their transformation for 3 years. Our findings revealed multiple identities, disorientation, a perceived sense of meaninglessness, loss and eventual regain in confidence, gain in pedagogical knowledge and skill, and changed perceptions of the social roles of science teachers and scientists. Driven by personal choice or need (financial, intellectual), such transformations were achieved through active pursuit of meaning in one's work, critical assessment of assumptions, planning, and trying on the unfamiliar role of a science teacher. It is argued that such transition entails complex changes in thinking about science teaching and identifying oneself as a science teacher.

The case for transforming governmental public health.

PubMed

Salinsky, Eileen; Gursky, Elin A

2006-01-01

Changing threats to the public's health necessitate a profound transformation of the public health enterprise. Despite recent attention to the biodefense role of public health, policymakers have not developed a clear, realistic vision for the structure and functionality of the governmental public health system. Lack of leadership and organizational disconnects across levels of government have prevented strategic alignment of resources and undermined momentum for meaningful change. A transformed public health system is needed to address the demands of emergency preparedness and health protection. Such transformation should include focused, risk-based resource allocation; regional planning; technological upgrades; workforce restructuring; improved integration of private-sector assets; and better performance monitoring.

Engaging blind and partially sighted stakeholders in transformational change.

PubMed

Pearson, Victoria

2016-09-01

For non-profit organizations in the disability sector, engaging stakeholders with disabilities on matters of strategic planning is both a responsibility and an expectation. As part of our current strategic plan, which calls for organizational and systemic transformation, the Canadian National Institute for the Blind (CNIB) has engaged blind and partially sighted stakeholders alongside other interest groups to build and advocate for a more holistic model of vision healthcare and rehabilitation. This article describes the CNIB's multi-year process, including early-stage consultations, collaborative strategy development, and political advocacy and shares our organization's key success factors and learnings in creating meaningful, mutually beneficial engagement. © 2016 The Canadian College of Health Leaders.

The Coordinate Transformation Method of High Resolution dem Data

NASA Astrophysics Data System (ADS)

Yan, Chaode; Guo, Wang; Li, Aimin

2018-04-01

Coordinate transformation methods of DEM data can be divided into two categories. One reconstruct based on original vector elevation data. The other transforms DEM data blocks by transforming parameters. But the former doesn't work in the absence of original vector data, and the later may cause errors at joint places between adjoining blocks of high resolution DEM data. In view of this problem, a method dealing with high resolution DEM data coordinate transformation is proposed. The method transforms DEM data into discrete vector elevation points, and then adjusts positions of points by bi-linear interpolation respectively. Finally, a TIN is generated by transformed points, and the new DEM data in target coordinate system is reconstructed based on TIN. An algorithm which can find blocks and transform automatically is given in this paper. The method is tested in different terrains and proved to be feasible and valid.

Synergizing health and population in Pakistan.

PubMed

Nishtar, Sania; Amjad, Saba; Sheikh, Sobia; Ahmad, Mahbub

2009-09-01

The delivery of health and family planning services in Pakistan is the respective mandate of the Ministry of Health/departments of health and the Ministry of Population Welfare. This institutional separation creates issues due to marginalization of family planning and reproductive health as core health issues. The government of Pakistan has made several attempts in the past to merge both the institutional hierarchal arrangements. This study was conducted to examine if merger is a viable option and to explore a way forward to bridge the current population-health disconnect in the country. Qualitative survey methods, inclusive of review of published and grey literature, archival analysis, informant interviews and focus group discussions were used for the analysis. Findings outline both the imperatives for merging the ministries and the challenges inherent in doing so. Recommendations recognize that although not a sufficient step to improve health and population outcomes, creating synergies between the health and population sectors is an imperative. The sustainable long-term solution to the existing population-health disconnect centres on deep-rooted reform at several levels in both the institutional hierarchies, with transformation of the role of stewardship agencies and reengineering of service delivery arrangements as its hallmarks. Restructured service delivery arrangements are meant to allow the delivery of a set of MDG+ services, where family planning and reproductive health are grouped alongside and together with essential health services. The latter are envisaged to be a yardstick for public delivery of services and the basis of contractual relationships in new management arrangements, which involve a role for the private sector. The short to medium term strategies proposed in this paper centre on a range of specific collaborative measures with a view to building capacity for the broader systems transformation. Sustained political and institutional commitment will be needed to implement these recommendations.

Transforming Student Affairs Strategic Planning into Tangible Results

ERIC Educational Resources Information Center

Taylor, Simone Himbeault; Matney, Malinda M.

2007-01-01

The Division of Student Affairs at the University of Michigan has engaged in an iterative strategic process to create and implement a set of long-range goals. This strategic journey continues to evolve, bringing together the guiding framework of strategic planning steps, a reflective process with an assessment component within each step, and a…

A Model for Planning Vocational Education at the Local Level. Information Series No. 153.

ERIC Educational Resources Information Center

Bregman, Ralph

One of a series of sixteen knowledge transformation papers, this paper presents an educational planning model which incorporates citizen involvement at the local level and provides a more responsive and efficient vocational education system. In the first section techniques are discussed for encouraging community participation, such as general…

One Smithsonian: Greater Reach, Greater Relevance, Profound Impact. Annual Performance Plan, Fiscal Year 2018

ERIC Educational Resources Information Center

Smithsonian Institution, 2018

2018-01-01

In December 2017, the Smithsonian unveiled a new Strategic Plan. It expands on the "Grand Challenges"--Unlocking the Mysteries of the Universe, Understanding and Sustaining a Biodiverse Planet, Valuing World Cultures, Understanding the American Experience, and Magnifying the Transformative Power of Arts and Design--by setting goals to…

78 FR 45934 - The National Institute of Dental and Craniofacial Research (NIDCR) Strategic Plan Request for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-30

... a new strategic plan to guide the Institute's research efforts and priorities over the next six... areas identified below. (1) ``Transformative'' areas of research where new discoveries could have the greatest benefit for advancing dental, oral, and craniofacial research. (2) New technical capabilities or...

10 CFR Appendix B to Subpart K of... - Sampling Plan for Enforcement Testing

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Sampling Plan for Enforcement Testing B Appendix B to Subpart K of Part 431 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL EQUIPMENT Distribution Transformers Pt. 431, Subpt. K, App. B Appendix B...

10 CFR Appendix B to Subpart K of... - Sampling Plan for Enforcement Testing

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 3 2011-01-01 2011-01-01 false Sampling Plan for Enforcement Testing B Appendix B to Subpart K of Part 431 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL EQUIPMENT Distribution Transformers Pt. 431, Subpt. K, App. B Appendix B...

Transformation of a Community College Budgeting Process Driven by the Strategic Plan

ERIC Educational Resources Information Center

Portmann, Renee R.

2017-01-01

Community colleges are unique in the higher education realm. Open access, the demographics of students, communities served, locations, and funding sources all present distinct circumstances. A strategic plan supported by leadership, faculty, staff and the external environment is needed to steer students on pathways to success. The focus on…

Remote sensing for restoration planning: how the big picture can inform stakeholders

Treesearch

Susan Cordell; Erin J. Questad; Gregory P. Asner; Kealoha M. Kinney; Jarrod M. Thaxton; Amanda Uowolo; Sam Brooks; Mark W. Chynoweth

2016-01-01

The use of remote sensing in ecosystem management has transformed how land managers, practitioners, and policymakers evaluate ecosystem loss, gain, and change at multiple spatial and temporal scales. Less developed is the use of these spatial tools for planning, implementing, and evaluating ecosystem restoration projects and especially so in multifunctional...

Pay Now, Learn Later.

ERIC Educational Resources Information Center

Schwartz, John

1986-01-01

Duquesne University's pay-now, learn-later plan is one device that could transform college-fee payment almost as much as the GI Bill did. The further away from college age the child, the more the school earns and the deeper the discount. Some other options are discussed including installment plans and special sales on tuition. (MLW)

Comparison of the convolution quadrature method and enhanced inverse FFT with application in elastodynamic boundary element method

NASA Astrophysics Data System (ADS)

Schanz, Martin; Ye, Wenjing; Xiao, Jinyou

2016-04-01

Transient problems can often be solved with transformation methods, where the inverse transformation is usually performed numerically. Here, the discrete Fourier transform in combination with the exponential window method is compared with the convolution quadrature method formulated as inverse transformation. Both are inverse Laplace transforms, which are formally identical but use different complex frequencies. A numerical study is performed, first with simple convolution integrals and, second, with a boundary element method (BEM) for elastodynamics. Essentially, when combined with the BEM, the discrete Fourier transform needs less frequency calculations, but finer mesh compared to the convolution quadrature method to obtain the same level of accuracy. If further fast methods like the fast multipole method are used to accelerate the boundary element method the convolution quadrature method is better, because the iterative solver needs much less iterations to converge. This is caused by the larger real part of the complex frequencies necessary for the calculation, which improves the conditions of system matrix.

Responsiveness of Higher Education to Changing Job Market Demand in Bangladesh

ERIC Educational Resources Information Center

Dutta, Bipasha; Islam, Kazi Maruful

2017-01-01

Bangladesh economy has been transforming towards a market-based economy from a state-dominated centrally planned economy since the early 1980s, the pace of transformation has been slow though. The aim of this article is to see how the higher education system responds to the changes in the structure of the economy. The article argues that the…

Transforming a High School Media Center into a Library Learning Commons

ERIC Educational Resources Information Center

Chiara, Nancy A.

2014-01-01

This study outlines a planned action based research project focused on studying the transformation of an urban high school media center to a learning commons model. This study includes a descriptive account as well as the impact of steps taken to match the media center to the needs of the 21st century learner. The research focuses on shifting…

Designing the Ideal School as a Transformative Process: An Approach to Promoting Teacher Identity in Pre-Service Teachers

ERIC Educational Resources Information Center

Zur, Ayala; Ravid, Rachel

2018-01-01

This paper presents an approach to planning academic courses for pre-service teachers and for researching development of teacher identity. The approach was implemented in a course, conducted in an Israeli Master Teach program, designed to foster pre-service teacher identity transformation. The research described here addresses two questions: (1)…

Biological Inquiry: A New Course and Assessment Plan in Response to the Call to Transform Undergraduate Biology

ERIC Educational Resources Information Center

Goldey, Ellen S.; Abercrombie, Clarence L.; Ivy, Tracie M.; Kusher, Dave I.; Moeller, John F.; Rayner, Doug A.; Smith, Charles F.; Spivey, Natalie W.

2012-01-01

We transformed our first-year curriculum in biology with a new course, Biological Inquiry, in which greater than 50% of all incoming, first-year students enroll. The course replaced a traditional, content-driven course that relied on outdated approaches to teaching and learning. We diversified pedagogical practices by adopting guided inquiry in…

Five Systematic Transformations and Their Impacts on Academic Profession in China

ERIC Educational Resources Information Center

Dan, Mao; Fengqiao, Yan

2015-01-01

The dynamism of contemporary Chinese society reflects itself in higher education and the academic profession. The remarkable changes in the past 30 years include the shifting from a planned system to a market system on one hand, and the shifting from a closed system to an open system on the other hand. Five obvious transformations in higher…

Instructional Transformation: How Do Teaching and Learning Change with a One-to-One Laptop Implementation?

ERIC Educational Resources Information Center

Branch, John C., IV.

2014-01-01

A one-to-one computing initiative was implemented at high school in rural southern West Virginia in 2011. The program was implemented with limited time for planning and professional development. Teachers had to anticipate the implications the innovation had for instructional transformation and the impact the laptops would have on the learners. The…

3D kinematics using dual quaternions: theory and applications in neuroscience

PubMed Central

Leclercq, Guillaume; Lefèvre, Philippe; Blohm, Gunnar

2013-01-01

In behavioral neuroscience, many experiments are developed in 1 or 2 spatial dimensions, but when scientists tackle problems in 3-dimensions (3D), they often face problems or new challenges. Results obtained for lower dimensions are not always extendable in 3D. In motor planning of eye, gaze or arm movements, or sensorimotor transformation problems, the 3D kinematics of external (stimuli) or internal (body parts) must often be considered: how to describe the 3D position and orientation of these objects and link them together? We describe how dual quaternions provide a convenient way to describe the 3D kinematics for position only (point transformation) or for combined position and orientation (through line transformation), easily modeling rotations, translations or screw motions or combinations of these. We also derive expressions for the velocities of points and lines as well as the transformation velocities. Then, we apply these tools to a motor planning task for manual tracking and to the modeling of forward and inverse kinematics of a seven-dof three-link arm to show the interest of dual quaternions as a tool to build models for these kinds of applications. PMID:23443667

Impact assessment of land use planning driving forces on environment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Longgao, E-mail: chenlonggao@163.com; Yang, Xiaoyan; School of Environment and Spatial Informatics, China University of Mining and Technology, Xuzhou 221116

Land use change may exert a negative impact on environmental quality. A state–impact–state (SIS) model describing a state transform under certain impacts has been integrated into land use planning (LUP) environmental impact assessment (LUPEA). This logical model is intuitive and easy to understand, but the exploration of impact is essential to establish the indicator system and to identify the scope of land use environmental impact when it is applied to a specific region. In this study, we investigated environmental driving forces from land use planning (LUPF), along with the conception, components, scope, and impact of LUPF. This method was illustratedmore » by a case study in Zoucheng, China. Through the results, we concluded that (1) the LUPF on environment are impacts originated from the implementation of LUP on a regional environment, which are characterized by four aspects: magnitude, direction, action point, and its owner; (2) various scopes of LUPF on individual environmental elements based on different standards jointly define the final scope of LUPEA; (3) our case study in Zoucheng demonstrates the practicability of this proposed approach; (4) this method can be embedded into LUPEA with direction, magnitudes, and scopes of the LUPF on individual elements obtained, and the identified indicator system can be directly employed into LUPEA and (5) the assessment helps to identify key indicators and to set up a corresponding strategy to mitigate the negative impact of LUP on the environment, which are two important objectives of strategic environmental assessment (SEA) in LUP. - Highlights: • Environmental driving forces from land use planning (LUPF) are investigated and categorized. • Our method can obtains the direction, magnitudes and scopes of environmental driving forces. • The LUPEA scope is determined by the combination of various scopes of LUPF on individual elements. • LUPF assessment can be embedded into LUPEA. • The method can help to identify key indicators and set up a strategy to mitigate negative environmental impact.« less

Gaussian Quadrature is an efficient method for the back-transformation in estimating the usual intake distribution when assessing dietary exposure.

PubMed

Dekkers, A L M; Slob, W

2012-10-01

In dietary exposure assessment, statistical methods exist for estimating the usual intake distribution from daily intake data. These methods transform the dietary intake data to normal observations, eliminate the within-person variance, and then back-transform the data to the original scale. We propose Gaussian Quadrature (GQ), a numerical integration method, as an efficient way of back-transformation. We compare GQ with six published methods. One method uses a log-transformation, while the other methods, including GQ, use a Box-Cox transformation. This study shows that, for various parameter choices, the methods with a Box-Cox transformation estimate the theoretical usual intake distributions quite well, although one method, a Taylor approximation, is less accurate. Two applications--on folate intake and fruit consumption--confirmed these results. In one extreme case, some methods, including GQ, could not be applied for low percentiles. We solved this problem by modifying GQ. One method is based on the assumption that the daily intakes are log-normally distributed. Even if this condition is not fulfilled, the log-transformation performs well as long as the within-individual variance is small compared to the mean. We conclude that the modified GQ is an efficient, fast and accurate method for estimating the usual intake distribution. Copyright © 2012 Elsevier Ltd. All rights reserved.

Fast frequency domain method to detect skew in a document image

NASA Astrophysics Data System (ADS)

Mehta, Sunita; Walia, Ekta; Dutta, Maitreyee

2015-12-01

In this paper, a new fast frequency domain method based on Discrete Wavelet Transform and Fast Fourier Transform has been implemented for the determination of the skew angle in a document image. Firstly, image size reduction is done by using two-dimensional Discrete Wavelet Transform and then skew angle is computed using Fast Fourier Transform. Skew angle error is almost negligible. The proposed method is experimented using a large number of documents having skew between -90° and +90° and results are compared with Moments with Discrete Wavelet Transform method and other commonly used existing methods. It has been determined that this method works more efficiently than the existing methods. Also, it works with typed, picture documents having different fonts and resolutions. It overcomes the drawback of the recently proposed method of Moments with Discrete Wavelet Transform that does not work with picture documents.

Exact Solution of Gas Dynamics Equations Through Reduced Differential Transform and Sumudu Transform Linked with Pades Approximants

NASA Astrophysics Data System (ADS)

Rao, T. R. Ramesh

2018-04-01

In this paper, we study the analytical method based on reduced differential transform method coupled with sumudu transform through Pades approximants. The proposed method may be considered as alternative approach for finding exact solution of Gas dynamics equation in an effective manner. This method does not require any discretization, linearization and perturbation.

FFT-enhanced IHS transform method for fusing high-resolution satellite images

USGS Publications Warehouse

Ling, Y.; Ehlers, M.; Usery, E.L.; Madden, M.

2007-01-01

Existing image fusion techniques such as the intensity-hue-saturation (IHS) transform and principal components analysis (PCA) methods may not be optimal for fusing the new generation commercial high-resolution satellite images such as Ikonos and QuickBird. One problem is color distortion in the fused image, which causes visual changes as well as spectral differences between the original and fused images. In this paper, a fast Fourier transform (FFT)-enhanced IHS method is developed for fusing new generation high-resolution satellite images. This method combines a standard IHS transform with FFT filtering of both the panchromatic image and the intensity component of the original multispectral image. Ikonos and QuickBird data are used to assess the FFT-enhanced IHS transform method. Experimental results indicate that the FFT-enhanced IHS transform method may improve upon the standard IHS transform and the PCA methods in preserving spectral and spatial information. ?? 2006 International Society for Photogrammetry and Remote Sensing, Inc. (ISPRS).

Image-based path planning for automated virtual colonoscopy navigation

NASA Astrophysics Data System (ADS)

Hong, Wei

2008-03-01

Virtual colonoscopy (VC) is a noninvasive method for colonic polyp screening, by reconstructing three-dimensional models of the colon using computerized tomography (CT). In virtual colonoscopy fly-through navigation, it is crucial to generate an optimal camera path for efficient clinical examination. In conventional methods, the centerline of the colon lumen is usually used as the camera path. In order to extract colon centerline, some time consuming pre-processing algorithms must be performed before the fly-through navigation, such as colon segmentation, distance transformation, or topological thinning. In this paper, we present an efficient image-based path planning algorithm for automated virtual colonoscopy fly-through navigation without the requirement of any pre-processing. Our algorithm only needs the physician to provide a seed point as the starting camera position using 2D axial CT images. A wide angle fisheye camera model is used to generate a depth image from the current camera position. Two types of navigational landmarks, safe regions and target regions are extracted from the depth images. Camera position and its corresponding view direction are then determined using these landmarks. The experimental results show that the generated paths are accurate and increase the user comfort during the fly-through navigation. Moreover, because of the efficiency of our path planning algorithm and rendering algorithm, our VC fly-through navigation system can still guarantee 30 FPS.

Identification of material constants for piezoelectric transformers by three-dimensional, finite-element method and a design-sensitivity method.

PubMed

Joo, Hyun-Woo; Lee, Chang-Hwan; Rho, Jong-Seok; Jung, Hyun-Kyo

2003-08-01

In this paper, an inversion scheme for piezoelectric constants of piezoelectric transformers is proposed. The impedance of piezoelectric transducers is calculated using a three-dimensional finite element method. The validity of this is confirmed experimentally. The effects of material coefficients on piezoelectric transformers are investigated numerically. Six material coefficient variables for piezoelectric transformers were selected, and a design sensitivity method was adopted as an inversion scheme. The validity of the proposed method was confirmed by step-up ratio calculations. The proposed method is applied to the analysis of a sample piezoelectric transformer, and its resonance characteristics are obtained by numerically combined equivalent circuit method.

Understanding NETCOM and Its Role in the 21st Century

DTIC Science & Technology

2007-03-30

information dominance goals that directly support transformation efforts. This project examines the reasons why NETCOM/9th ASC was created, reviews its unique organizational structure and mission, and outlines its role in the Army’s overarching transformation in the 21st century. Although the research reveals that NETCOM/9th ASC’s strategic plans and objectives are nested to support the Army’s transformation efforts, the lack of Army senior leader familiarity with this organization could put at risk some of the programs that support the implementation of its

Transforming home health nursing with telehealth technology.

PubMed

Farrar, Francisca Cisneros

2015-06-01

Telehealth technology is an evidence-based delivery model tool that can be integrated into the plan of care for mental health patients. Telehealth technology empowers access to health care, can help decrease or prevent hospital readmissions, assist home health nurses provide shared decision making, and focuses on collaborative care. Telehealth and the recovery model have transformed the role of the home health nurse. Nurses need to be proactive and respond to rapidly emerging technologies that are transforming their role in home care. Copyright © 2015 Elsevier Inc. All rights reserved.

Dispersion interference in the pulsed-wire measurement method

NASA Astrophysics Data System (ADS)

Shahal, O.; Elkonin, B. V.; Sokolowski, J. S.

1990-10-01

The magnetic profile of the wiggler to be used in the planned Weizmann Institute FEL has been measured using the pulsed-wire method. The main transverse deflection pattern caused by an electrical current pulse in a wire placed along the wiggler was sometimes accompanied by minor faster and slower parasitic components. These components interfered with the main profile, resulting in distorted mapping of the wiggler magnetic field. Their periodical structure being very close to the main pattern could not be easily resolved by applying a numerical Fourier transform. A strong correlation between the wire tension and the amplitude of the parasitic patterns was found. Significant damping of these oscillations was achieved by applying high enough tension to the wire (close the yield point), allowing to disregard their contribution to the measurement accuracy.

A method of power analysis based on piecewise discrete Fourier transform

NASA Astrophysics Data System (ADS)

Xin, Miaomiao; Zhang, Yanchi; Xie, Da

2018-04-01

The paper analyzes the existing feature extraction methods. The characteristics of discrete Fourier transform and piecewise aggregation approximation are analyzed. Combining with the advantages of the two methods, a new piecewise discrete Fourier transform is proposed. And the method is used to analyze the lighting power of a large customer in this paper. The time series feature maps of four different cases are compared with the original data, discrete Fourier transform, piecewise aggregation approximation and piecewise discrete Fourier transform. This new method can reflect both the overall trend of electricity change and its internal changes in electrical analysis.

Comprehensive reliability allocation method for CNC lathes based on cubic transformed functions of failure mode and effects analysis

NASA Astrophysics Data System (ADS)

Yang, Zhou; Zhu, Yunpeng; Ren, Hongrui; Zhang, Yimin

2015-03-01

Reliability allocation of computerized numerical controlled(CNC) lathes is very important in industry. Traditional allocation methods only focus on high-failure rate components rather than moderate failure rate components, which is not applicable in some conditions. Aiming at solving the problem of CNC lathes reliability allocating, a comprehensive reliability allocation method based on cubic transformed functions of failure modes and effects analysis(FMEA) is presented. Firstly, conventional reliability allocation methods are introduced. Then the limitations of direct combination of comprehensive allocation method with the exponential transformed FMEA method are investigated. Subsequently, a cubic transformed function is established in order to overcome these limitations. Properties of the new transformed functions are discussed by considering the failure severity and the failure occurrence. Designers can choose appropriate transform amplitudes according to their requirements. Finally, a CNC lathe and a spindle system are used as an example to verify the new allocation method. Seven criteria are considered to compare the results of the new method with traditional methods. The allocation results indicate that the new method is more flexible than traditional methods. By employing the new cubic transformed function, the method covers a wider range of problems in CNC reliability allocation without losing the advantages of traditional methods.

A study of stress-induced phase transformation and micromechanical behavior of CuZr-based alloy by in-situ neutron diffraction

DOE PAGES

Wang, Dongmei; Mu, Juan; Chen, Yan; ...

2017-03-01

The stress-induced phase transformation and micromechanical behavior of CuZr-based alloy were investigated by in-situ neutron diffraction. The pseudoelastic behavior with a pronounced strain-hardening effect is observed. The retained martensite nuclei and the residual stress obtained from the 1st cycle reduce the stress threshold for the martensitic transformation. A critical stress level is required for the reverse martensitic transformation from martensite to B2 phase. An increase of intensity for the B2 (110) plane in the 1st cycle is caused by the twinning along the {112}<111> twinning system. The convoluted stress partitioning influenced by the elastic and transformation anisotropy along with themore » newly formed martensite determines the microstress partitioning of the studied CuZr-based alloy. The reversible martensitic transformation is responsible for the pseudoelasticity. The macro mechanical behavior of the pure B2 phase can be divided into 3 stages, which are mediated by the evolvement of the martensitic transformation. This manuscript has been authored by UT-Battelle, LLC under Contract No. DE-AC05-00OR22725 with the U.S. Department of Energy. The United States Government retains and the publisher, by accepting the article for publication, acknowledges that the United States Government retains a non-exclusive, paid-up, irrevocable, world-wide license to publish or reproduce the published form of this manuscript, or allow others to do so, for United States Government purposes. The Department of Energy will provide public access to these results of federally sponsored research in accordance with the DOE Public Access Plan (http://energy.gov/downloads/doe-public-access-plan).« less

A study of stress-induced phase transformation and micromechanical behavior of CuZr-based alloy by in-situ neutron diffraction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Dongmei; Mu, Juan; Chen, Yan

The stress-induced phase transformation and micromechanical behavior of CuZr-based alloy were investigated by in-situ neutron diffraction. The pseudoelastic behavior with a pronounced strain-hardening effect is observed. The retained martensite nuclei and the residual stress obtained from the 1st cycle reduce the stress threshold for the martensitic transformation. A critical stress level is required for the reverse martensitic transformation from martensite to B2 phase. An increase of intensity for the B2 (110) plane in the 1st cycle is caused by the twinning along the {112}<111> twinning system. The convoluted stress partitioning influenced by the elastic and transformation anisotropy along with themore » newly formed martensite determines the microstress partitioning of the studied CuZr-based alloy. The reversible martensitic transformation is responsible for the pseudoelasticity. The macro mechanical behavior of the pure B2 phase can be divided into 3 stages, which are mediated by the evolvement of the martensitic transformation. This manuscript has been authored by UT-Battelle, LLC under Contract No. DE-AC05-00OR22725 with the U.S. Department of Energy. The United States Government retains and the publisher, by accepting the article for publication, acknowledges that the United States Government retains a non-exclusive, paid-up, irrevocable, world-wide license to publish or reproduce the published form of this manuscript, or allow others to do so, for United States Government purposes. The Department of Energy will provide public access to these results of federally sponsored research in accordance with the DOE Public Access Plan (http://energy.gov/downloads/doe-public-access-plan).« less

A Transfer Voltage Simulation Method for Generator Step Up Transformers

NASA Astrophysics Data System (ADS)

Funabashi, Toshihisa; Sugimoto, Toshirou; Ueda, Toshiaki; Ametani, Akihiro

It has been found from measurements for 13 sets of GSU transformers that a transfer voltage of a generator step-up (GSU) transformer involves one dominant oscillation frequency. The frequency can be estimated from the inductance and capacitance values of the GSU transformer low-voltage-side. This observation has led to a new method for simulating a GSU transformer transfer voltage. The method is based on the EMTP TRANSFORMER model, but stray capacitances are added. The leakage inductance and the magnetizing resistance are modified using approximate curves for their frequency characteristics determined from the measured results. The new method is validated in comparison with the measured results.

Computing Instantaneous Frequency by normalizing Hilbert Transform

NASA Technical Reports Server (NTRS)

Huang, Norden E. (Inventor)

2005-01-01

This invention presents Normalized Amplitude Hilbert Transform (NAHT) and Normalized Hilbert Transform(NHT), both of which are new methods for computing Instantaneous Frequency. This method is designed specifically to circumvent the limitation set by the Bedorsian and Nuttal Theorems, and to provide a sharp local measure of error when the quadrature and the Hilbert Transform do not agree. Motivation for this method is that straightforward application of the Hilbert Transform followed by taking the derivative of the phase-angle as the Instantaneous Frequency (IF) leads to a common mistake made up to this date. In order to make the Hilbert Transform method work, the data has to obey certain restrictions.

Computing Instantaneous Frequency by normalizing Hilbert Transform

DOEpatents

Huang, Norden E.

2005-05-31

This invention presents Normalized Amplitude Hilbert Transform (NAHT) and Normalized Hilbert Transform(NHT), both of which are new methods for computing Instantaneous Frequency. This method is designed specifically to circumvent the limitation set by the Bedorsian and Nuttal Theorems, and to provide a sharp local measure of error when the quadrature and the Hilbert Transform do not agree. Motivation for this method is that straightforward application of the Hilbert Transform followed by taking the derivative of the phase-angle as the Instantaneous Frequency (IF) leads to a common mistake made up to this date. In order to make the Hilbert Transform method work, the data has to obey certain restrictions.

Electrosprayed chitosan nanoparticles: facile and efficient approach for bacterial transformation

NASA Astrophysics Data System (ADS)

Abyadeh, Morteza; Sadroddiny, Esmaeil; Ebrahimi, Ammar; Esmaeili, Fariba; Landi, Farzaneh Saeedi; Amani, Amir

2017-12-01

A rapid and efficient procedure for DNA transformation is a key prerequisite for successful cloning and genomic studies. While there are efforts to develop a facile method, so far obtained efficiencies for alternative methods have been unsatisfactory (i.e. 105-106 CFU/μg plasmid) compared with conventional method (up to 108 CFU/μg plasmid). In this work, for the first time, we prepared chitosan/pDNA nanoparticles by electrospraying methods to improve transformation process. Electrospray method was used for chitosan/pDNA nanoparticles production to investigate the non-competent bacterial transformation efficiency; besides, the effect of chitosan molecular weight, N/P ratio and nanoparticle size on non-competent bacterial transformation efficiency was evaluated too. The results showed that transformation efficiency increased with decreasing the molecular weight, N/P ratio and nanoparticles size. In addition, transformation efficiency of 1.7 × 108 CFU/μg plasmid was obtained with chitosan molecular weight, N/P ratio and nanoparticles size values of 30 kDa, 1 and 125 nm. Chitosan/pDNA electrosprayed nanoparticles were produced and the effect of molecular weight, N/P and size of nanoparticles on transformation efficiency was evaluated. In total, we present a facile and rapid method for bacterial transformation, which has comparable efficiency with the common method.

Empty tracks optimization based on Z-Map model

NASA Astrophysics Data System (ADS)

Liu, Le; Yan, Guangrong; Wang, Zaijun; Zang, Genao

2017-12-01

For parts with many features, there are more empty tracks during machining. If these tracks are not optimized, the machining efficiency will be seriously affected. In this paper, the characteristics of the empty tracks are studied in detail. Combining with the existing optimization algorithm, a new tracks optimization method based on Z-Map model is proposed. In this method, the tool tracks are divided into the unit processing section, and then the Z-Map model simulation technique is used to analyze the order constraint between the unit segments. The empty stroke optimization problem is transformed into the TSP with sequential constraints, and then through the genetic algorithm solves the established TSP problem. This kind of optimization method can not only optimize the simple structural parts, but also optimize the complex structural parts, so as to effectively plan the empty tracks and greatly improve the processing efficiency.

Online adaptation and verification of VMAT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crijns, Wouter, E-mail: wouter.crijns@uzleuven.be; Defraene, Gilles; Depuydt, Tom

2015-07-15

Purpose: This work presents a method for fast volumetric modulated arc therapy (VMAT) adaptation in response to interfraction anatomical variations. Additionally, plan parameters extracted from the adapted plans are used to verify the quality of these plans. The methods were tested as a prostate class solution and compared to replanning and to their current clinical practice. Methods: The proposed VMAT adaptation is an extension of their previous intensity modulated radiotherapy (IMRT) adaptation. It follows a direct (forward) planning approach: the multileaf collimator (MLC) apertures are corrected in the beam’s eye view (BEV) and the monitor units (MUs) are corrected usingmore » point dose calculations. All MLC and MU corrections are driven by the positions of four fiducial points only, without need for a full contour set. Quality assurance (QA) of the adapted plans is performed using plan parameters that can be calculated online and that have a relation to the delivered dose or the plan quality. Five potential parameters are studied for this purpose: the number of MU, the equivalent field size (EqFS), the modulation complexity score (MCS), and the components of the MCS: the aperture area variability (AAV) and the leaf sequence variability (LSV). The full adaptation and its separate steps were evaluated in simulation experiments involving a prostate phantom subjected to various interfraction transformations. The efficacy of the current VMAT adaptation was scored by target mean dose (CTV{sub mean}), conformity (CI{sub 95%}), tumor control probability (TCP), and normal tissue complication probability (NTCP). The impact of the adaptation on the plan parameters (QA) was assessed by comparison with prediction intervals (PI) derived from a statistical model of the typical variation of these parameters in a population of VMAT prostate plans (n = 63). These prediction intervals are the adaptation equivalent of the tolerance tables for couch shifts in the current clinical practice. Results: The proposed adaptation of a two-arc VMAT plan resulted in the intended CTV{sub mean} (Δ ≤ 3%) and TCP (ΔTCP ≤ 0.001). Moreover, the method assures the intended CI{sub 95%} (Δ ≤ 11%) resulting in lowered rectal NTCP for all cases. Compared to replanning, their adaptation is faster (13 s vs 10 min) and more intuitive. Compared to the current clinical practice, it has a better protection of the healthy tissue. Compared to IMRT, VMAT is more robust to anatomical variations, but it is also less sensitive to the different correction steps. The observed variations of the plan parameters in their database included a linear dependence on the date of treatment planning and on the target radius. The MCS is not retained as QA metric due to a contrasting behavior of its components (LSV and AAV). If three out of four plan parameters (MU, EqFS, AAV, and LSV) need to lie inside a 50% prediction interval (3/4—50%PI), all adapted plans will be accepted. In contrast, all replanned plans do not meet this loose criterion, mainly because they have no connection to the initially optimized and verified plan. Conclusions: A direct (forward) VMAT adaptation performs equally well as (inverse) replanning but is faster and can be extended to real-time adaptation. The prediction intervals for the machine parameters are equivalent to the tolerance tables for couch shifts in the current clinical practice. A 3/4—50%PI QA criterion accepts all the adapted plans but rejects all the replanned plans.« less

Combined chemical and physical transformation method with RbCl and sepiolite for the transformation of various bacterial species.

PubMed

Ren, Jun; Lee, Haram; Yoo, Seung Min; Yu, Myeong-Sang; Park, Hansoo; Na, Dokyun

2017-04-01

DNA transformation that delivers plasmid DNAs into bacterial cells is fundamental in genetic manipulation to engineer and study bacteria. Developed transformation methods to date are optimized to specific bacterial species for high efficiency. Thus, there is always a demand for simple and species-independent transformation methods. We herein describe the development of a chemico-physical transformation method that combines a rubidium chloride (RbCl)-based chemical method and sepiolite-based physical method, and report its use for the simple and efficient delivery of DNA into various bacterial species. Using this method, the best transformation efficiency for Escherichia coli DH5α was 4.3×10 6 CFU/μg of pUC19 plasmid, which is higher than or comparable to the reported transformation efficiencies to date. This method also allowed the introduction of plasmid DNAs into Bacillus subtilis (5.7×10 3 CFU/μg of pSEVA3b67Rb), Bacillus megaterium (2.5×10 3 CFU/μg of pSPAsp-hp), Lactococcus lactis subsp. lactis (1.0×10 2 CFU/μg of pTRKH3-ermGFP), and Lactococcus lactis subsp. cremoris (2.2×10 2 CFU/μg of pMSP3535VA). Remarkably, even when the conventional chemical and physical methods failed to generate transformed cells in Bacillus sp. and Enterococcus faecalis, E. malodoratus and E. mundtii, our combined method showed a significant transformation efficiency (2.4×10 4 , 4.5×10 2 , 2×10 1 , and 0.5×10 1 CFU/μg of plasmid DNA). Based on our results, we anticipate that our simple and efficient transformation method should prove usefulness for introducing DNA into various bacterial species without complicated optimization of parameters affecting DNA entry into the cell. Copyright © 2017. Published by Elsevier B.V.

Marketing urbanistyczny jako instrument aktywizacji turystyki

NASA Astrophysics Data System (ADS)

Polska, Anna

2009-01-01

In the paper there are two studies of cases of council individuals from the Lublin voivodship presented. In order to stimulate the development of tourism and socio-economic activation, authorities of both communes applied in the tools of town-planning marketing. Presented instruments are: the strategy of socio-economic development and the many years' plan of development. Particular attention was paid to modernization of spatial structure and transformation in the sphere of town-planning as well as architecture.

Bladder segmentation in MR images with watershed segmentation and graph cut algorithm

NASA Astrophysics Data System (ADS)

Blaffert, Thomas; Renisch, Steffen; Schadewaldt, Nicole; Schulz, Heinrich; Wiemker, Rafael

2014-03-01

Prostate and cervix cancer diagnosis and treatment planning that is based on MR images benefit from superior soft tissue contrast compared to CT images. For these images an automatic delineation of the prostate or cervix and the organs at risk such as the bladder is highly desirable. This paper describes a method for bladder segmentation that is based on a watershed transform on high image gradient values and gray value valleys together with the classification of watershed regions into bladder contents and tissue by a graph cut algorithm. The obtained results are superior if compared to a simple region-after-region classification.

An Analysis Plan for the ARCOMS II (Armor Combat Operations Model Support II) Experiment.

DTIC Science & Technology

1983-06-01

In order to facilitate Armor Combat Modeling, the data analysis shculd focus upon the methods which transform the data intc descriptive or predictive ...discussed in Chapter III tc predict the Farameter for probability of detection in time ŕt. This should be compared with the results of the N.4gh -t Vision...J 6A 46.) I-I 0 f U-CL 0~ z o -Z 06 09 03 v 0 0 SJldnYS 10 ON Ipgr Cp o LSTm n at emn itgas 4AA rI z ;A (AZ - 090.0 UlA0 -O ON 404 Fiur CAd &P CC

California's "Gold Standard" for Higher Education Falls Upon Hard Times

ERIC Educational Resources Information Center

Keller, Josh

2009-01-01

Few documents in higher education have enjoyed the influence or longevity of the California Master Plan for Higher Education, the 1960 law that transformed the state's public colleges and served as a blueprint for public systems across the country. Even today, almost 50 years after it was written, the master plan retains a mythic status in…

Preventing Dust Collection: Transforming Student Affairs Strategic Planning into Tangible Results

ERIC Educational Resources Information Center

Taylor, Simone Himbeault; Matney, Malinda M.

2007-01-01

The Division of Student Affairs at the University of Michigan in Ann Arbor engaged in an iterative strategic process to create and implement a set of long-range goals. This strategic journey continues to evolve, uniting a guiding framework of strategic planning steps, a reflective process with an assessment component within each step, and a group…

Determining Distance Education Students' Readiness for Mobile Learning at University of Ghana Using the Theory of Planned Behavior

ERIC Educational Resources Information Center

Tagoe, Michael Ayitey; Abakah, Ellen

2014-01-01

The use of mobile technologies in the classroom is transforming teaching and learning in higher institutions. This study investigated University of Ghana Distance Education students' perceptions toward mobile learning. The paper using the theory of planned behaviour (TPB) explained how students' beliefs influenced students' intention to adopt…

Cyclic stress induced phase transformation in super-bainitic microstructure

NASA Astrophysics Data System (ADS)

Xiu, Wencui; Han, Ying; Liu, Cheng; Wu, Hua; Liu, Yunxu

2017-03-01

Not Available Project supported by the National Natural Science Foundation of China (Grant Nos. 51171030 and 51604034), the Scientific and Technological Planning Project of Jilin Province, China (Grant No. 20150520030JH), and the Scientific and Technological Research Fund of Jilin Provincial Education Department during the Twelfth Five-year Plan Period, China (Grant No. 2015-95).

Planning Urban Education: New Ideas and Techniques to Transform Learning in the City.

ERIC Educational Resources Information Center

Roberts, Dennis L., II, Ed.

This volume contains a number of articles which examine the crisis in urban education from a scientific, technological, and "total systems" frame of reference, and propose new strategies for making schools more effective and cities more livable. Urban education is viewed within the context of a total urban community system. Management, planning,…

Where Is the Gap between Internationalisation Strategic Planning and Its Implementation? A Study of 16 Dutch Universities' Internationalisation Plans

ERIC Educational Resources Information Center

de Haan, Helen Haijing

2014-01-01

A dominant concern with internationalisation through the past decades has been the process of strategic transformation of universities. While strategic management has been perceived as a necessary and useful approach in the construction of internationalisation, many criticisms have been levelled against the application of strategic management in…

A Tale of Two Regions: Landscape Ecological Planning for Shale Gas Energy Futures

NASA Astrophysics Data System (ADS)

Murtha, T., Jr.; Schroth, O.; Orland, B.; Goldberg, L.; Mazurczyk, T.

2015-12-01

As we increasingly embrace deep shale gas deposits to meet global energy demands new and dispersed local and regional policy and planning challenges emerge. Even in regions with long histories of energy extraction, such as coal, shale gas and the infrastructure needed to produce the gas and transport it to market offers uniquely complex transformations in land use and landcover not previously experienced. These transformations are fast paced, dispersed and can overwhelm local and regional planning and regulatory processes. Coupled to these transformations is a structural confounding factor. While extraction and testing are carried out locally, regulation and decision-making is multilayered, often influenced by national and international factors. Using a geodesign framework, this paper applies a set of geospatial landscape ecological planning tools in two shale gas settings. First, we describe and detail a series of ongoing studies and tools that we have developed for communities in the Marcellus Shale region of the eastern United States, specifically the northern tier of Pennsylvania. Second, we apply a subset of these tools to potential gas development areas of the Fylde region in Lancashire, United Kingdom. For the past five years we have tested, applied and refined a set of place based and data driven geospatial models for forecasting, envisioning, analyzing and evaluating shale gas activities in northern Pennsylvania. These models are continuously compared to important landscape ecological planning challenges and priorities in the region, e.g. visual and cultural resource preservation. Adapting and applying these tools to a different landscape allow us to not only isolate and define important regulatory and policy exigencies in each specific setting, but also to develop and refine these models for broader application. As we continue to explore increasingly complex energy solutions globally, we need an equally complex comparative set of landscape ecological planning tools to inform policy, design and regional planning. Adapting tools and techniques developed in Pennsylvania where shale gas extraction is ongoing to Lancashire, where industry is still in the exploratory phase offers a key opportunity to test and refine more generalizable models.

The Filtered Abel Transform and Its Application in Combustion Diagnostics

NASA Technical Reports Server (NTRS)

Simons, Stephen N. (Technical Monitor); Yuan, Zeng-Guang

2003-01-01

Many non-intrusive combustion diagnosis methods generate line-of-sight projections of a flame field. To reconstruct the spatial field of the measured properties, these projections need to be deconvoluted. When the spatial field is axisymmetric, commonly used deconvolution method include the Abel transforms, the onion peeling method and the two-dimensional Fourier transform method and its derivatives such as the filtered back projection methods. This paper proposes a new approach for performing the Abel transform method is developed, which possesses the exactness of the Abel transform and the flexibility of incorporating various filters in the reconstruction process. The Abel transform is an exact method and the simplest among these commonly used methods. It is evinced in this paper that all the exact reconstruction methods for axisymmetric distributions must be equivalent to the Abel transform because of its uniqueness and exactness. Detailed proof is presented to show that the two dimensional Fourier methods when applied to axisymmetric cases is identical to the Abel transform. Discrepancies among various reconstruction method stem from the different approximations made to perform numerical calculations. An equation relating the spectrum of a set of projection date to that of the corresponding spatial distribution is obtained, which shows that the spectrum of the projection is equal to the Abel transform of the spectrum of the corresponding spatial distribution. From the equation, if either the projection or the distribution is bandwidth limited, the other is also bandwidth limited, and both have the same bandwidth. If the two are not bandwidth limited, the Abel transform has a bias against low wave number components in most practical cases. This explains why the Abel transform and all exact deconvolution methods are sensitive to high wave number noises. The filtered Abel transform is based on the fact that the Abel transform of filtered projection data is equal to an integral transform of the original projection data with the kernel function being the Abel transform of the filtering function. The kernel function is independent of the projection data and can be obtained separately when the filtering function is selected. Users can select the best filtering function for a particular set of experimental data. When the kernal function is obtained, it can be used repeatedly to a number of projection data sets (rovs) from the same experiment. When an entire flame image that contains a large number of projection lines needs to be processed, the new approach significantly reduces computational effort in comparison with the conventional approach in which each projection data set is deconvoluted separately. Computer codes have been developed to perform the filter Abel transform for an entire flame field. Measured soot volume fraction data of a jet diffusion flame are processed as an example.

ESSA: Will Adding a Nonacademic Accountability Indicator Enhance Student and Learning Supports? Research for School Improvement and Transformation. Center Report

ERIC Educational Resources Information Center

Center for Mental Health in Schools at UCLA, 2016

2016-01-01

As Congress recognized in passing the "Every Student Succeeds Act", it is time for school improvement to encompass policy and planning that enables every school to replace the outdated patchwork of programs and services used in addressing barriers to learning and teaching. The way to do this involves transforming student and learning…

Overview of Models Used in Land Treatment of Wastewater

DTIC Science & Technology

1982-03-01

The limitation of the ratio of fecal califorms to total coliphage as a water pollution index. Water Resources, vol. 10, p. 745-748. Bouma, J. (1981...predicting.Ar water and salt transport in soils, 2)-nitrogen transport and transformations, 3) phosphorus transport and transformations, 4r-virus...1 Models for planning, site selection and cost analysis .......... 2 Models for predicting water and salt transport in soils

Organizational Change in the U.S. Customs and Border Protection Agency

DTIC Science & Technology

2012-05-17

requirements. Models of organizational change, like the Burke- Litwin model, facilitate an assessment of CBP’s transformation because they identify factors...valuable insight. The Burke- Litwin model offers a framework for prioritizing the organizational factors of change. Others outline the importance of an...implementation plan first and then assesses CBP’s efforts against the Burke- Litwin model which stresses transformational factors: strategy, leadership, and

Predictive Validity of the Suicide Trigger Scale (STS-3) for Post-Discharge Suicide Attempt in High-Risk Psychiatric Inpatients

PubMed Central

Yaseen, Zimri S.; Kopeykina, Irina; Gutkovich, Zinoviy; Bassirnia, Anahita; Cohen, Lisa J.; Galynker, Igor I.

2014-01-01

Background The greatly increased risk of suicide after psychiatric hospitalization is a critical problem, yet we are unable to identify individuals who would attempt suicide upon discharge. The Suicide Trigger Scale v.3 (STS-3), was designed to measure the construct of an affective ‘suicide trigger state’ hypothesized to precede a suicide attempt (SA). This study aims to test the predictive validity of the STS-3 for post-discharge SA on a high-risk psychiatric-inpatient sample. Methods The STS-3, and a psychological test battery measuring suicidality, mood, impulsivity, trauma history, and attachment style were administered to 161 adult psychiatric patients hospitalized following suicidal ideation (SI) or SA. Receiver Operator Characteristic and logistic regression analyses were used to assess prediction of SA in the 6-month period following discharge from hospitalization. Results STS-3 scores for the patients who made post-discharge SA followed a bimodal distribution skewed to high and low scores, thus a distance from median transform was applied to the scores. The transformed score was a significant predictor of post-discharge SA (AUC 0.731), and a subset of six STS-3 scale items was identified that produced improved prediction of post-discharge SA (AUC 0.814). Scores on C-SSRS and BSS were not predictive. Patients with ultra-high (90th percentile) STS-3 scores differed significantly from ultra-low (10th percentile) scorers on measures of affective intensity, depression, impulsiveness, abuse history, and attachment security. Conclusion STS-3 transformed scores at admission to the psychiatric hospital predict suicide attempts following discharge among the high-risk group of suicidal inpatients. Patients with high transformed scores appear to comprise two clinically distinct groups; an impulsive, affectively intense, fearfully attached group with high raw STS-3 scores and a low-impulsivity, low affect and low trauma-reporting group with low raw STS-3 scores. These groups may correspond to low-plan and planned suicide attempts, respectively, but this remains to be established by future research. PMID:24466229

The KS Method in Light of Generalized Euler Parameters.

DTIC Science & Technology

1980-01-01

motion for the restricted two-body problem is trans- formed via the Kustaanheimo - Stiefel transformation method (KS) into a dynamical equation in the... Kustaanheimo - Stiefel2 transformation method (KS) in the two-body problem. Many papers have appeared in which specific problems or applications have... TRANSFORMATION MATRIX P. Kustaanheimo and E. Stiefel2 proposed a regularization method by intro- ducing a 4 x 4 transformation matrix and four-component

General method for designing wave shape transformers.

PubMed

Ma, Hua; Qu, Shaobo; Xu, Zhuo; Wang, Jiafu

2008-12-22

An effective method for designing wave shape transformers (WSTs) is investigated by adopting the coordinate transformation theory. Following this method, the devices employed to transform electromagnetic (EM) wave fronts from one style with arbitrary shape and size to another style, can be designed. To verify this method, three examples in 2D spaces are also presented. Compared with the methods proposed in other literatures, this method offers the general procedure in designing WSTs, and thus is of great importance for the potential and practical applications possessed by such kinds of devices.

Transitioning From Volume to Value: One Academic Medical Center's Approach to Improving Population Health.

PubMed

Halvorson, Stephanie A C; Tanski, Mary E; Yackel, Thomas R

2017-05-01

The U.S. health care system is undergoing a major transformation. Clinical delivery systems are now being paid according to the value of the care they provide, in accordance with the Triple Aim, which incorporates improving the quality and cost of care and the patient experience. Increasingly, financial risk is being transferred from insurers to clinical delivery systems that become responsible for both episode-based clinical care and the longitudinal care of patients. Thus, these delivery systems need to develop strategies to manage the health of populations. Academic medical centers (AMCs) serve a unique role in many markets yet may be ill prepared for this transformation. In 2013, Oregon Health & Science University (OHSU) partnered with a large health insurer and six other hospitals across the state to form Propel Health, a collaborative partnership designed to deliver the tools, methods, and support necessary for population health management. OHSU also developed new internal structures and transformed its business model to embrace this value-based care model. Each Propel Health partner included the employees and dependents enrolled in its employee medical plan, for approximately 55,000 covered individuals initially. By 2017, Propel Health is expected to cover 110,000 individuals. Other outcomes to measure in the future include the quality and cost of care provided under this partnership. Anticipated challenges to overcome include insufficient primary care networks, conflicting incentives, local competition, and the magnitude of the transformation. Still, the time is right for AMCs to commit to improving the health of populations.

Enhancing Sustainable Communities With Green Infrastructure

EPA Pesticide Factsheets

This publication aims to help local governments, water utilities, nonprofit organizations, neighborhood groups, and other stakeholders integrate green infrastructure strategies into plans that can transform their communities.

Semilinear programming: applications and implementation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mohan, S.

Semilinear programming is a method of solving optimization problems with linear constraints where the non-negativity restrictions on the variables are dropped and the objective function coefficients can take on different values depending on whether the variable is positive or negative. The simplex method for linear programming is modified in this thesis to solve general semilinear and piecewise linear programs efficiently without having to transform them into equivalent standard linear programs. Several models in widely different areas of optimization such as production smoothing, facility locations, goal programming and L/sub 1/ estimation are presented first to demonstrate the compact formulation that arisesmore » when such problems are formulated as semilinear programs. A code SLP is constructed using the semilinear programming techniques. Problems in aggregate planning and L/sub 1/ estimation are solved using SLP and equivalent linear programs using a linear programming simplex code. Comparisons of CPU times and number iterations indicate SLP to be far superior. The semilinear programming techniques are extended to piecewise linear programming in the implementation of the code PLP. Piecewise linear models in aggregate planning are solved using PLP and equivalent standard linear programs using a simple upper bounded linear programming code SUBLP.« less

ERISTAR: Earth Resources Information Storage, Transformation, Analysis, and Retrieval

NASA Technical Reports Server (NTRS)

1972-01-01

The National Aeronautics and Space Administration (NASA) and the American Society for Engineering Education (ASEE) have sponsored faculty fellowship programs in systems engineering design for the past several years. During the summer of 1972 four such programs were conducted by NASA, with Auburn University cooperating with Marshall Space Flight Center (MSFC). The subject for the Auburn-MSFC design group was ERISTAR, an acronym for Earth Resources Information Storage, Transformation, Analysis and Retrieval, which represents an earth resources information management network of state information centers administered by the respective states and linked to federally administered regional centers and a national center. The considerations for serving the users and the considerations that must be given to processing data from a variety of sources are described. The combination of these elements into a national network is discussed and an implementation plan is proposed for a prototype state information center. The compatibility of the proposed plan with the Department of Interior plan, RALI, is indicated.

Regional energy planning: Some suggestions to public administration

NASA Astrophysics Data System (ADS)

Sozzi, R.

A methodology is proposed to estimate the relevant data and to improve the energy efficiency in regional energy planning. The quantification of the regional energy system is subdivided in three independent parameters which are separetely estimated: energy demand, energy consumption, and transformation capacity. Definitions and estimating procedures are given. The optimization of the regional planning includes the application, wherever possible, of the technologies which centralize the space-heating energy production or combine the production of electric energy with space-heating energy distribution.

Discrete Fourier transforms of nonuniformly spaced data

NASA Technical Reports Server (NTRS)

Swan, P. R.

1982-01-01

Time series or spatial series of measurements taken with nonuniform spacings have failed to yield fully to analysis using the Discrete Fourier Transform (DFT). This is due to the fact that the formal DFT is the convolution of the transform of the signal with the transform of the nonuniform spacings. Two original methods are presented for deconvolving such transforms for signals containing significant noise. The first method solves a set of linear equations relating the observed data to values defined at uniform grid points, and then obtains the desired transform as the DFT of the uniform interpolates. The second method solves a set of linear equations relating the real and imaginary components of the formal DFT directly to those of the desired transform. The results of numerical experiments with noisy data are presented in order to demonstrate the capabilities and limitations of the methods.

Category's analysis and operational project capacity method of transformation in design

NASA Astrophysics Data System (ADS)

Obednina, S. V.; Bystrova, T. Y.

2015-10-01

The method of transformation is attracting widespread interest in fields such contemporary design. However, in theory of design little attention has been paid to a categorical status of the term "transformation". This paper presents the conceptual analysis of transformation based on the theory of form employed in the influential essays by Aristotle and Thomas Aquinas. In the present work the transformation as a method of shaping design has been explored as well as potential application of this term in design has been demonstrated.

Application of Time-Frequency Domain Transform to Three-Dimensional Interpolation of Medical Images.

PubMed

Lv, Shengqing; Chen, Yimin; Li, Zeyu; Lu, Jiahui; Gao, Mingke; Lu, Rongrong

2017-11-01

Medical image three-dimensional (3D) interpolation is an important means to improve the image effect in 3D reconstruction. In image processing, the time-frequency domain transform is an efficient method. In this article, several time-frequency domain transform methods are applied and compared in 3D interpolation. And a Sobel edge detection and 3D matching interpolation method based on wavelet transform is proposed. We combine wavelet transform, traditional matching interpolation methods, and Sobel edge detection together in our algorithm. What is more, the characteristics of wavelet transform and Sobel operator are used. They deal with the sub-images of wavelet decomposition separately. Sobel edge detection 3D matching interpolation method is used in low-frequency sub-images under the circumstances of ensuring high frequency undistorted. Through wavelet reconstruction, it can get the target interpolation image. In this article, we make 3D interpolation of the real computed tomography (CT) images. Compared with other interpolation methods, our proposed method is verified to be effective and superior.

Beyond the Facade of Language Planning for Nepalese Primary Education: Monolingual Hangover, Elitism and Displacement of Local Languages?

ERIC Educational Resources Information Center

Phyak, Prem Bahadur

2011-01-01

The recent political transformation of Nepal from a constitutional monarchy to a federal democratic republic and from a Hindu polity to a secular country has brought about some crucial changes in language planning. The Interim Constitution of Nepal has not only recognized the multilingual and multicultural reality of the country but has also…

Education Stimulus Funds: An Opportunity to Plan Ahead

ERIC Educational Resources Information Center

Shakrani, Sharif

2009-01-01

Designed to stimulate the economy and employment, the "American Recovery and Reinvestment Act of 2009" (ARRA), commonly referred to as the stimulus package or plan, is a crucial step in a massive effort to create and save 3 to 4 million jobs, jump-start the U.S. economy and begin the process of transforming the economy for the 21st…

Strategic Mobility 21 Project Management Plan

DTIC Science & Technology

2006-09-29

California Association of Governments (SCAG), and other stakeholders to transform the former military installation into a modern in-land distribution node... governments , including adversary governments , and may be exported. c. This statement may not be used on technical documents that formerly were...required updates of both the ICD and the Technical Plan. SM21 has established a consortium of public and private, governmental and non

Transforming Barriers into Bridges: The Benefits of a Student-Driven Accessibility Planning Committee. Practice Brief

ERIC Educational Resources Information Center

Cragg, Stephanie J.; Carter, Irene; Nikolova, Kristina

2013-01-01

The School of Social Work and Disability Studies Accessibility Planning Committee (APC) is a student-driven initiative that has been in existence for over 10 years. This practice brief looked at the committee through interviews with faculty and student members. The investigation aimed to determine whether the benefits of having a student-driven…

Budgeting for National Defense Acquisition: Assessing System Linkage and the Impact of Transformation

DTIC Science & Technology

2005-06-30

which develops the Strategic Planning Guidance (SPG). The SPC is led by SECDEF and made up of the Senior Leaders Review Group (SLRG) and the...ASSESSING SYSTEM LINKAGE AND THE IMPACT OF TRANSFORMATION 30 JUNE 2005 by Lawrence R. Jones, Professor, Wagner Chair Graduate School of Business ...Public Policy Jerry McCaffery, Professor Graduate School of Business & Public Policy Kory L. Fierstine, Commander, United States Navy

The Power of the Frame: Systems Transformation Framework for Health Care Leaders.

PubMed

Scott, Kathy A; Pringle, Janice

Health care leaders are responsible for oversight of multiple and competing change interventions. These interventions regularly fail to achieve the desired outcomes and/or sustainable results. This often occurs because of the mental models and approaches that are used to plan, design, implement, and evaluate the system. These do not account for inherent characteristics that determine the system's likely ability to innovate while maintaining operational effectiveness. Theories exist on how to assess a system's readiness to change, but the definitions, constructs, and assessments are diverse and often look at facets of systems in isolation. The Systems Transformation Framework prescriptively defines and characterizes system domains on the basis of complex adaptive systems theory so that domains can be assessed in tandem. As a result, strengths and challenges to implementation are recognized before implementation begins. The Systems Transformation Framework defines 8 major domains: vision, leadership, organizational culture, organizational behavior, organizational structure, performance measurements, internal learning, and external learning. Each domain has principles that are critical for creating the conditions that lead to successful organizational adaptation and change. The Systems Transformation Framework can serve as a guide for health care leaders at all levels of the organization to (1) create environments that are change ready and (2) plan, design, implement, and evaluate change within complex adaptive systems.

Transforming to a computerized system for nursing care: organizational success within Magnet idealism.

PubMed

Lindgren, Carolyn L; Elie, Leslie G; Vidal, Elizabeth C; Vasserman, Alex

2010-01-01

In reaching the goal for standardized, quality care, a not-for-profit healthcare system consisting of seven institutional entities is transforming nursing practice guidelines, patient care workflow, and patient documents into electronic, online, real-time modalities for use across departments and all healthcare delivery entities of the system. Organizational structure and a strategic plan were developed for the 2-year Clinical Transformation Project. The Siemens Patient Care Document System was adopted and adapted to the hospitals' documentation and information needs. Two fast-track sessions of more than 100 nurses and representatives from other health disciplines were held to standardize assessments, histories, care protocols, and interdisciplinary plans of care for the top 10 diagnostic regulatory groups. Education needs of the users were addressed. After the first year, a productive, functional system is evidenced. For example, the bar-coded Medication Administration Check System is in full use on the clinical units of one of the hospitals, and the other institutional entities are at substantial stages of implementation of Patient Care Documentation System. The project requires significant allocation of personnel and financial resources for a highly functional informatics system that will transform clinical care. The project exemplifies four of the Magnet ideals and serves as a model for others who may be deciding about launching a similar endeavor.

A dose error evaluation study for 4D dose calculations

NASA Astrophysics Data System (ADS)

Milz, Stefan; Wilkens, Jan J.; Ullrich, Wolfgang

2014-10-01

Previous studies have shown that respiration induced motion is not negligible for Stereotactic Body Radiation Therapy. The intrafractional breathing induced motion influences the delivered dose distribution on the underlying patient geometry such as the lung or the abdomen. If a static geometry is used, a planning process for these indications does not represent the entire dynamic process. The quality of a full 4D dose calculation approach depends on the dose coordinate transformation process between deformable geometries. This article provides an evaluation study that introduces an advanced method to verify the quality of numerical dose transformation generated by four different algorithms. The used transformation metric value is based on the deviation of the dose mass histogram (DMH) and the mean dose throughout dose transformation. The study compares the results of four algorithms. In general, two elementary approaches are used: dose mapping and energy transformation. Dose interpolation (DIM) and an advanced concept, so called divergent dose mapping model (dDMM), are used for dose mapping. The algorithms are compared to the basic energy transformation model (bETM) and the energy mass congruent mapping (EMCM). For evaluation 900 small sample regions of interest (ROI) are generated inside an exemplary lung geometry (4DCT). A homogeneous fluence distribution is assumed for dose calculation inside the ROIs. The dose transformations are performed with the four different algorithms. The study investigates the DMH-metric and the mean dose metric for different scenarios (voxel sizes: 8 mm, 4 mm, 2 mm, 1 mm 9 different breathing phases). dDMM achieves the best transformation accuracy in all measured test cases with 3-5% lower errors than the other models. The results of dDMM are reasonable and most efficient in this study, although the model is simple and easy to implement. The EMCM model also achieved suitable results, but the approach requires a more complex programming structure. The study discloses disadvantages for the bETM and for the DIM. DIM yielded insufficient results for large voxel sizes, while bETM is prone to errors for small voxel sizes.

A dose error evaluation study for 4D dose calculations.

PubMed

Milz, Stefan; Wilkens, Jan J; Ullrich, Wolfgang

2014-11-07

Previous studies have shown that respiration induced motion is not negligible for Stereotactic Body Radiation Therapy. The intrafractional breathing induced motion influences the delivered dose distribution on the underlying patient geometry such as the lung or the abdomen. If a static geometry is used, a planning process for these indications does not represent the entire dynamic process. The quality of a full 4D dose calculation approach depends on the dose coordinate transformation process between deformable geometries. This article provides an evaluation study that introduces an advanced method to verify the quality of numerical dose transformation generated by four different algorithms.The used transformation metric value is based on the deviation of the dose mass histogram (DMH) and the mean dose throughout dose transformation. The study compares the results of four algorithms. In general, two elementary approaches are used: dose mapping and energy transformation. Dose interpolation (DIM) and an advanced concept, so called divergent dose mapping model (dDMM), are used for dose mapping. The algorithms are compared to the basic energy transformation model (bETM) and the energy mass congruent mapping (EMCM). For evaluation 900 small sample regions of interest (ROI) are generated inside an exemplary lung geometry (4DCT). A homogeneous fluence distribution is assumed for dose calculation inside the ROIs. The dose transformations are performed with the four different algorithms.The study investigates the DMH-metric and the mean dose metric for different scenarios (voxel sizes: 8 mm, 4 mm, 2 mm, 1 mm; 9 different breathing phases). dDMM achieves the best transformation accuracy in all measured test cases with 3-5% lower errors than the other models. The results of dDMM are reasonable and most efficient in this study, although the model is simple and easy to implement. The EMCM model also achieved suitable results, but the approach requires a more complex programming structure. The study discloses disadvantages for the bETM and for the DIM. DIM yielded insufficient results for large voxel sizes, while bETM is prone to errors for small voxel sizes.

Monitoring the effects of land cover change on the supply of ecosystem services in an urban region: A study of Santiago-Valparaíso, Chile

PubMed Central

de la Barrera, Francisco; Salazar, Alejandro; Inostroza, Luis

2017-01-01

Mankind’s quest for well-being results in continuous pressure to transform landscapes, with said transformation driven by land use changes, urbanization, production activity, and protective measures in addition to climate variability and other environmental drivers. The relationship between anthropogenic landscape changes and the provision of ecosystem services (ES) is a topic of increasing interest in Latin America. In Chile, land cover changes due to increased urbanization and forestry, and expansion of agricultural land, in addition to conservation initiatives as a part of land planning, have been intensive in the last few decades. In this study, the effects of anthropogenic landscape changes on the supply of ES were analyzed for the urban region of Santiago-Valparaiso (Chile) using a method based on expert consultation and land cover change assessment. A pool of experts scored the potential of specific land covers to provide certain ES. The results enabled calculation and mapping of changes in the potential of the landscape to supply ES. The aforementioned changes over a period of 15 years were evaluated. The results indicate a tenuous balance between positive and negative changes to the supply of ES derived from land cover changes. Understanding and reporting how these processes occur in urban regions contributes to the conservation of valuable landscapes through spatial planning tools, especially in areas close to housing developments and sensitive ecosystems. PMID:29136016

Monitoring the effects of land cover change on the supply of ecosystem services in an urban region: A study of Santiago-Valparaíso, Chile.

PubMed

Montoya-Tangarife, Claudia; de la Barrera, Francisco; Salazar, Alejandro; Inostroza, Luis

2017-01-01

Mankind's quest for well-being results in continuous pressure to transform landscapes, with said transformation driven by land use changes, urbanization, production activity, and protective measures in addition to climate variability and other environmental drivers. The relationship between anthropogenic landscape changes and the provision of ecosystem services (ES) is a topic of increasing interest in Latin America. In Chile, land cover changes due to increased urbanization and forestry, and expansion of agricultural land, in addition to conservation initiatives as a part of land planning, have been intensive in the last few decades. In this study, the effects of anthropogenic landscape changes on the supply of ES were analyzed for the urban region of Santiago-Valparaiso (Chile) using a method based on expert consultation and land cover change assessment. A pool of experts scored the potential of specific land covers to provide certain ES. The results enabled calculation and mapping of changes in the potential of the landscape to supply ES. The aforementioned changes over a period of 15 years were evaluated. The results indicate a tenuous balance between positive and negative changes to the supply of ES derived from land cover changes. Understanding and reporting how these processes occur in urban regions contributes to the conservation of valuable landscapes through spatial planning tools, especially in areas close to housing developments and sensitive ecosystems.

Semester-long inquiry-based molecular biology laboratory: Transcriptional regulation in yeast.

PubMed

Oelkers, Peter M

2017-03-04

A single semester molecular biology laboratory has been developed in which students design and execute a project examining transcriptional regulation in Saccharomyces cerevisiae. Three weeks of planning are allocated to developing a hypothesis through literature searches and use of bioinformatics. Common experimental plans address a cell process and how three genes that encode for proteins involved in that process are transcriptionally regulated in response to changing environmental conditions. Planning includes designing oligonucleotides to amplify the putative promoters of the three genes of interest. After the PCR, each product is cloned proximal to β-galactosidase in a yeast reporter plasmid. Techniques used include agarose electrophoresis, extraction of DNA from agarose, plasmid purification from bacteria, restriction digestion, ligation, and bacterial transformation. This promoter/reporter plasmid is then transformed into yeast. Transformed yeast are cultured in conditions prescribed in the experimental design, lysed and β-galactosidase activity is measured. The course provides an independent research experience in a group setting. Notebooks are maintained on-line with regular feedback. Projects culminate with the presentation of a poster worth 60% of the grade. Over the last three years, about 65% of students met expectations for experimental design, data acquisition, and analysis. © 2016 by The International Union of Biochemistry and Molecular Biology, 45(2):145-151, 2017. © 2016 The International Union of Biochemistry and Molecular Biology.

Acquisition and generalization of visuomotor transformations by nonhuman primates.

PubMed

Paz, Rony; Nathan, Chen; Boraud, Thomas; Bergman, Hagai; Vaadia, Eilon

2005-02-01

The kinematics of straight reaching movements can be specified vectorially by the direction of the movement and its extent. To explore the representation in the brain of these two properties, psychophysical studies have examined learning of visuomotor transformations of either rotation or gain and their generalization. However, the neuronal substrates of such complex learning are only beginning to be addressed. As an initial step in ensuring the validity of such investigations, it must be shown that monkeys indeed learn and generalize visuomotor transformations in the same manner as humans. Here, we analyze trajectories and velocities of movements as monkeys adapt to either rotational or gain transformations. We used rotations with different signs and magnitudes, and gains with different signs, and analyzed transfer of learning to untrained movements. The results show that monkeys can adapt to both types of transformation with a time course that resembles human learning. Analysis of the aftereffects reveals that rotation is learned locally and generalizes poorly to untrained directions, whereas gain is learned more globally and can be transferred to other amplitudes. The results lend additional support to the hypothesis that reaching movements are learned locally but can be easily rescaled to other magnitudes by scaling the peak velocity. The findings also indicate that reaching movements in monkeys are planned and executed very similarly to those in humans. This validates the underlying presumption that neuronal recordings in primates can help elucidate the mechanisms of motor learning in particular and motor planning in general.

Transformer Incipient Fault Prediction Using Combined Artificial Neural Network and Various Particle Swarm Optimisation Techniques.

PubMed

Illias, Hazlee Azil; Chai, Xin Rui; Abu Bakar, Ab Halim; Mokhlis, Hazlie

2015-01-01

It is important to predict the incipient fault in transformer oil accurately so that the maintenance of transformer oil can be performed correctly, reducing the cost of maintenance and minimise the error. Dissolved gas analysis (DGA) has been widely used to predict the incipient fault in power transformers. However, sometimes the existing DGA methods yield inaccurate prediction of the incipient fault in transformer oil because each method is only suitable for certain conditions. Many previous works have reported on the use of intelligence methods to predict the transformer faults. However, it is believed that the accuracy of the previously proposed methods can still be improved. Since artificial neural network (ANN) and particle swarm optimisation (PSO) techniques have never been used in the previously reported work, this work proposes a combination of ANN and various PSO techniques to predict the transformer incipient fault. The advantages of PSO are simplicity and easy implementation. The effectiveness of various PSO techniques in combination with ANN is validated by comparison with the results from the actual fault diagnosis, an existing diagnosis method and ANN alone. Comparison of the results from the proposed methods with the previously reported work was also performed to show the improvement of the proposed methods. It was found that the proposed ANN-Evolutionary PSO method yields the highest percentage of correct identification for transformer fault type than the existing diagnosis method and previously reported works.

Transformer Incipient Fault Prediction Using Combined Artificial Neural Network and Various Particle Swarm Optimisation Techniques

PubMed Central

2015-01-01

It is important to predict the incipient fault in transformer oil accurately so that the maintenance of transformer oil can be performed correctly, reducing the cost of maintenance and minimise the error. Dissolved gas analysis (DGA) has been widely used to predict the incipient fault in power transformers. However, sometimes the existing DGA methods yield inaccurate prediction of the incipient fault in transformer oil because each method is only suitable for certain conditions. Many previous works have reported on the use of intelligence methods to predict the transformer faults. However, it is believed that the accuracy of the previously proposed methods can still be improved. Since artificial neural network (ANN) and particle swarm optimisation (PSO) techniques have never been used in the previously reported work, this work proposes a combination of ANN and various PSO techniques to predict the transformer incipient fault. The advantages of PSO are simplicity and easy implementation. The effectiveness of various PSO techniques in combination with ANN is validated by comparison with the results from the actual fault diagnosis, an existing diagnosis method and ANN alone. Comparison of the results from the proposed methods with the previously reported work was also performed to show the improvement of the proposed methods. It was found that the proposed ANN-Evolutionary PSO method yields the highest percentage of correct identification for transformer fault type than the existing diagnosis method and previously reported works. PMID:26103634

Mental Health System Transformation: Drivers for Change, Organizational Preparation, Engaging Partners and Outcomes.

PubMed

Corring, Deborah J; Whittall, Sandy; MustinPowell, Jill; Jarmain, Sarah; Chapman, Patty; Sussman, Sam

2016-01-01

St. Joseph's Health Care London (hereafter referred to as St. Joseph's) is a publicly funded hospital that has led mental health (MH) service system transformation in south west Ontario following directives from the Health Services Restructuring Commission (HSRC) (Sinclair 2000). This paper documents how provincial policy; HSRC directives; use of change management activities; organizational planning; and partnerships with other hospitals, community agencies and LHINs drove, shaped and accomplished the transformational change. The transformation included divestment of beds and related ambulatory services to four other hospitals, closure of beds and employment services and the construction of two state-of-the-art facilities. This paper documents the tracking of system performance measures and the outcomes that resulted.

A Rapid Coordinate Transformation Method Applied in Industrial Robot Calibration Based on Characteristic Line Coincidence.

PubMed

Liu, Bailing; Zhang, Fumin; Qu, Xinghua; Shi, Xiaojia

2016-02-18

Coordinate transformation plays an indispensable role in industrial measurements, including photogrammetry, geodesy, laser 3-D measurement and robotics. The widely applied methods of coordinate transformation are generally based on solving the equations of point clouds. Despite the high accuracy, this might result in no solution due to the use of ill conditioned matrices. In this paper, a novel coordinate transformation method is proposed, not based on the equation solution but based on the geometric transformation. We construct characteristic lines to represent the coordinate systems. According to the space geometry relation, the characteristic line scan is made to coincide by a series of rotations and translations. The transformation matrix can be obtained using matrix transformation theory. Experiments are designed to compare the proposed method with other methods. The results show that the proposed method has the same high accuracy, but the operation is more convenient and flexible. A multi-sensor combined measurement system is also presented to improve the position accuracy of a robot with the calibration of the robot kinematic parameters. Experimental verification shows that the position accuracy of robot manipulator is improved by 45.8% with the proposed method and robot calibration.

A Rapid Coordinate Transformation Method Applied in Industrial Robot Calibration Based on Characteristic Line Coincidence

PubMed Central

Liu, Bailing; Zhang, Fumin; Qu, Xinghua; Shi, Xiaojia

2016-01-01

Coordinate transformation plays an indispensable role in industrial measurements, including photogrammetry, geodesy, laser 3-D measurement and robotics. The widely applied methods of coordinate transformation are generally based on solving the equations of point clouds. Despite the high accuracy, this might result in no solution due to the use of ill conditioned matrices. In this paper, a novel coordinate transformation method is proposed, not based on the equation solution but based on the geometric transformation. We construct characteristic lines to represent the coordinate systems. According to the space geometry relation, the characteristic line scan is made to coincide by a series of rotations and translations. The transformation matrix can be obtained using matrix transformation theory. Experiments are designed to compare the proposed method with other methods. The results show that the proposed method has the same high accuracy, but the operation is more convenient and flexible. A multi-sensor combined measurement system is also presented to improve the position accuracy of a robot with the calibration of the robot kinematic parameters. Experimental verification shows that the position accuracy of robot manipulator is improved by 45.8% with the proposed method and robot calibration. PMID:26901203

REGIONAL-SCALE WIND FIELD CLASSIFICATION EMPLOYING CLUSTER ANALYSIS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Glascoe, L G; Glaser, R E; Chin, H S

2004-06-17

The classification of time-varying multivariate regional-scale wind fields at a specific location can assist event planning as well as consequence and risk analysis. Further, wind field classification involves data transformation and inference techniques that effectively characterize stochastic wind field variation. Such a classification scheme is potentially useful for addressing overall atmospheric transport uncertainty and meteorological parameter sensitivity issues. Different methods to classify wind fields over a location include the principal component analysis of wind data (e.g., Hardy and Walton, 1978) and the use of cluster analysis for wind data (e.g., Green et al., 1992; Kaufmann and Weber, 1996). The goalmore » of this study is to use a clustering method to classify the winds of a gridded data set, i.e, from meteorological simulations generated by a forecast model.« less

Methods for transforming and expression screening of filamentous fungal cells with a DNA library

DOEpatents

Teter, Sarah; Lamsa, Michael; Cherry, Joel; Ward, Connie

2015-06-02

The present invention relates to methods for expression screening of filamentous fungal transformants, comprising: (a) isolating single colony transformants of a DNA library introduced into E. coli; (b) preparing DNA from each of the single colony E. coli transformants; (c) introducing a sample of each of the DNA preparations of step (b) into separate suspensions of protoplasts of a filamentous fungus to obtain transformants thereof, wherein each transformant contains one or more copies of an individual polynucleotide from the DNA library; (d) growing the individual filamentous fungal transformants of step (c) on selective growth medium, thereby permitting growth of the filamentous fungal transformants, while suppressing growth of untransformed filamentous fungi; and (e) measuring activity or a property of each polypeptide encoded by the individual polynucleotides. The present invention also relates to isolated polynucleotides encoding polypeptides of interest obtained by such methods, to nucleic acid constructs, expression vectors, and recombinant host cells comprising the isolated polynucleotides, and to methods of producing the polypeptides encoded by the isolated polynucleotides.

A Vision System For A Mars Rover

NASA Astrophysics Data System (ADS)

Wilcox, Brian H.; Gennery, Donald B.; Mishkin, Andrew H.; Cooper, Brian K.; Lawton, Teri B.; Lay, N. Keith; Katzmann, Steven P.

1987-01-01

A Mars rover must be able to sense its local environment with sufficient resolution and accuracy to avoid local obstacles and hazards while moving a significant distance each day. Power efficiency and reliability are extremely important considerations, making stereo correlation an attractive method of range sensing compared to laser scanning, if the computational load and correspondence errors can be handled. Techniques for treatment of these problems, including the use of more than two cameras to reduce correspondence errors and possibly to limit the computational burden of stereo processing, have been tested at JPL. Once a reliable range map is obtained, it must be transformed to a plan view and compared to a stored terrain database, in order to refine the estimated position of the rover and to improve the database. The slope and roughness of each terrain region are computed, which form the basis for a traversability map allowing local path planning. Ongoing research and field testing of such a system is described.

A vision system for a Mars rover

NASA Technical Reports Server (NTRS)

Wilcox, Brian H.; Gennery, Donald B.; Mishkin, Andrew H.; Cooper, Brian K.; Lawton, Teri B.; Lay, N. Keith; Katzmann, Steven P.

1988-01-01

A Mars rover must be able to sense its local environment with sufficient resolution and accuracy to avoid local obstacles and hazards while moving a significant distance each day. Power efficiency and reliability are extremely important considerations, making stereo correlation an attractive method of range sensing compared to laser scanning, if the computational load and correspondence errors can be handled. Techniques for treatment of these problems, including the use of more than two cameras to reduce correspondence errors and possibly to limit the computational burden of stereo processing, have been tested at JPL. Once a reliable range map is obtained, it must be transformed to a plan view and compared to a stored terrain database, in order to refine the estimated position of the rover and to improve the database. The slope and roughness of each terrain region are computed, which form the basis for a traversability map allowing local path planning. Ongoing research and field testing of such a system is described.

Automated flight path planning for virtual endoscopy.

PubMed

Paik, D S; Beaulieu, C F; Jeffrey, R B; Rubin, G D; Napel, S

1998-05-01

In this paper, a novel technique for rapid and automatic computation of flight paths for guiding virtual endoscopic exploration of three-dimensional medical images is described. While manually planning flight paths is a tedious and time consuming task, our algorithm is automated and fast. Our method for positioning the virtual camera is based on the medial axis transform but is much more computationally efficient. By iteratively correcting a path toward the medial axis, the necessity of evaluating simple point criteria during morphological thinning is eliminated. The virtual camera is also oriented in a stable viewing direction, avoiding sudden twists and turns. We tested our algorithm on volumetric data sets of eight colons, one aorta and one bronchial tree. The algorithm computed the flight paths in several minutes per volume on an inexpensive workstation with minimal computation time added for multiple paths through branching structures (10%-13% per extra path). The results of our algorithm are smooth, centralized paths that aid in the task of navigation in virtual endoscopic exploration of three-dimensional medical images.

Symbolic Constraint Maintenance Grid

NASA Technical Reports Server (NTRS)

James, Mark

2006-01-01

Version 3.1 of Symbolic Constraint Maintenance Grid (SCMG) is a software system that provides a general conceptual framework for utilizing pre-existing programming techniques to perform symbolic transformations of data. SCMG also provides a language (and an associated communication method and protocol) for representing constraints on the original non-symbolic data. SCMG provides a facility for exchanging information between numeric and symbolic components without knowing the details of the components themselves. In essence, it integrates symbolic software tools (for diagnosis, prognosis, and planning) with non-artificial-intelligence software. SCMG executes a process of symbolic summarization and monitoring of continuous time series data that are being abstractly represented as symbolic templates of information exchange. This summarization process enables such symbolic- reasoning computing systems as artificial- intelligence planning systems to evaluate the significance and effects of channels of data more efficiently than would otherwise be possible. As a result of the increased efficiency in representation, reasoning software can monitor more channels and is thus able to perform monitoring and control functions more effectively.

Explaining the role of organizational culture on succession-planning at the Ministry of Health and Medical Education: A qualitative study

PubMed Central

Mehrtak, Mohammad; Farzaneh, Esmaeil; Habibzadeh, Shahram; Kamran, Aziz; Zandian, Hamed; Mahdavi, Abdollah

2017-01-01

Background Developing and guiding new knowledge are futile unless the organizational culture can also be transformed. Future leaders cannot emerge out of an organizational environment that is not conducive to the accumulation of experiences. Objective The aim of this study was to explore the role of organizational culture in creating a succession-planning system at the Ministry of Health and Medical Education in 2014. Methods The present qualitative framework analysis held interviews with 23 director generals, administrative directors and deputies from the headquarters of the Iranian Ministry of Health and Medical Education in 2014 who were selected through snowball sampling. The data obtained were analyzed in MAXQDA-10. Codes were extracted using inductive techniques. Results The cultural factors affecting succession-planning at the Ministry of Health and Medical Education were identified and classified under three main areas, including the cultural factors related to the directors with four themes (Directors’ job security, Constructive competition, Transparency and trust development, Creating opportunities), to the personnel with four themes (Organizational identity and loyalty, Trust in the organization, Talent and merit, Peer envy) and to the system with two themes (Values and beliefs, Politicization). Conclusion Findings of the study show that establishment and institutionalization of the succession planning to the Ministry of Health and Medical Education is deeply affected by the components of organizational culture. Accordingly, unprofessional organization culture can deprive the organization of numerous advantages in multiple-succession planning. PMID:29403623

Learning linear transformations between counting-based and prediction-based word embeddings

PubMed Central

Hayashi, Kohei; Kawarabayashi, Ken-ichi

2017-01-01

Despite the growing interest in prediction-based word embedding learning methods, it remains unclear as to how the vector spaces learnt by the prediction-based methods differ from that of the counting-based methods, or whether one can be transformed into the other. To study the relationship between counting-based and prediction-based embeddings, we propose a method for learning a linear transformation between two given sets of word embeddings. Our proposal contributes to the word embedding learning research in three ways: (a) we propose an efficient method to learn a linear transformation between two sets of word embeddings, (b) using the transformation learnt in (a), we empirically show that it is possible to predict distributed word embeddings for novel unseen words, and (c) empirically it is possible to linearly transform counting-based embeddings to prediction-based embeddings, for frequent words, different POS categories, and varying degrees of ambiguities. PMID:28926629

Image encryption with chaotic map and Arnold transform in the gyrator transform domains

NASA Astrophysics Data System (ADS)

Sang, Jun; Luo, Hongling; Zhao, Jun; Alam, Mohammad S.; Cai, Bin

2017-05-01

An image encryption method combing chaotic map and Arnold transform in the gyrator transform domains was proposed. Firstly, the original secret image is XOR-ed with a random binary sequence generated by a logistic map. Then, the gyrator transform is performed. Finally, the amplitude and phase of the gyrator transform are permutated by Arnold transform. The decryption procedure is the inverse operation of encryption. The secret keys used in the proposed method include the control parameter and the initial value of the logistic map, the rotation angle of the gyrator transform, and the transform number of the Arnold transform. Therefore, the key space is large, while the key data volume is small. The numerical simulation was conducted to demonstrate the effectiveness of the proposed method and the security analysis was performed in terms of the histogram of the encrypted image, the sensitiveness to the secret keys, decryption upon ciphertext loss, and resistance to the chosen-plaintext attack.

Comparison and evaluation on image fusion methods for GaoFen-1 imagery

NASA Astrophysics Data System (ADS)

Zhang, Ningyu; Zhao, Junqing; Zhang, Ling

2016-10-01

Currently, there are many research works focusing on the best fusion method suitable for satellite images of SPOT, QuickBird, Landsat and so on, but only a few of them discuss the application of GaoFen-1 satellite images. This paper proposes a novel idea by using four fusion methods, such as principal component analysis transform, Brovey transform, hue-saturation-value transform, and Gram-Schmidt transform, from the perspective of keeping the original image spectral information. The experimental results showed that the transformed images by the four fusion methods not only retain high spatial resolution on panchromatic band but also have the abundant spectral information. Through comparison and evaluation, the integration of Brovey transform is better, but the color fidelity is not the premium. The brightness and color distortion in hue saturation-value transformed image is the largest. Principal component analysis transform did a good job in color fidelity, but its clarity still need improvement. Gram-Schmidt transform works best in color fidelity, and the edge of the vegetation is the most obvious, the fused image sharpness is higher than that of principal component analysis. Brovey transform, is suitable for distinguishing the Gram-Schmidt transform, and the most appropriate for GaoFen-1 satellite image in vegetation and non-vegetation area. In brief, different fusion methods have different advantages in image quality and class extraction, and should be used according to the actual application information and image fusion algorithm.

US effort on HTS power transformers

NASA Astrophysics Data System (ADS)

Mehta, S.

2011-11-01

Waukesha Electric Systems has been working in HTS power transformers development program under the auspices of US Government Department of Energy since 1994. This presentation will describe various milestones for this program and program history along with the lessons learned along the way. Our motivations for working on this development program based on man benefits offered by HTS power transformers to power delivery systems will be discussed. Based on various issues encountered during execution of many HTS projects, DOE has set up an independent program review process that is lead by team of experts. This team reviews are integral part of all DOE HTS projects. Success of all projects would be greatly enhanced by identifying critical issues early in the program. Requiring appropriate actions to mitigate the issues before processing further will lead to proactive interrogation and incorporation of expert's ideas in the project plans. Working of this review process will be also described in this presentation. Waukesha Electric Systems team including: Superpower-Inc, Oak Ridge National Laboratory, University of Houston Center for Superconductivity and Southern California Edison company was awarded a cost share grant by US Government in 2010 for development of a fault current limiting HTS power transformer. This multi year's program will require design, manufacture, installation, and monitoring of a 28 MVA tree phase transformer installed at Irvine CA. Smart Grid demonstration site. Transformer specifications along with requirements for fault current limiting and site requirement will be discussed. Design and development of various sub systems in support of this program including: HTS conductor performance specification, Dielectric system design approach, Dewar development for containing phase assemblies, cryo-cooling system design approach, etc. will be described. Finally; overall program schedule, critical milestone events, test plans and progress to date will be reported.

Efficacy Evaluation of Different Wavelet Feature Extraction Methods on Brain MRI Tumor Detection

NASA Astrophysics Data System (ADS)

Nabizadeh, Nooshin; John, Nigel; Kubat, Miroslav

2014-03-01

Automated Magnetic Resonance Imaging brain tumor detection and segmentation is a challenging task. Among different available methods, feature-based methods are very dominant. While many feature extraction techniques have been employed, it is still not quite clear which of feature extraction methods should be preferred. To help improve the situation, we present the results of a study in which we evaluate the efficiency of using different wavelet transform features extraction methods in brain MRI abnormality detection. Applying T1-weighted brain image, Discrete Wavelet Transform (DWT), Discrete Wavelet Packet Transform (DWPT), Dual Tree Complex Wavelet Transform (DTCWT), and Complex Morlet Wavelet Transform (CMWT) methods are applied to construct the feature pool. Three various classifiers as Support Vector Machine, K Nearest Neighborhood, and Sparse Representation-Based Classifier are applied and compared for classifying the selected features. The results show that DTCWT and CMWT features classified with SVM, result in the highest classification accuracy, proving of capability of wavelet transform features to be informative in this application.

Reliability Overhaul Model

DTIC Science & Technology

1989-08-01

Random variables for the conditional exponential distribution are generated using the inverse transform method. C1) Generate U - UCO,i) (2) Set s - A ln...e - [(x+s - 7)/ n] 0 + [Cx-T)/n]0 c. Random variables from the conditional weibull distribution are generated using the inverse transform method. C1...using a standard normal transformation and the inverse transform method. B - 3 APPENDIX 3 DISTRIBUTIONS SUPPORTED BY THE MODEL (1) Generate Y - PCX S

A Review of Transformer Aging and Control Strategies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gourisetti, Sri Nikhil Gup; Kirkham, Harold; Sivaraman, Deepak

Transformer aging is an important challenge in power system. Distribution transformers themselves are minimally controllable, but smart meters provide excellent, new insights into electrical loads, which insights can be used to understand and mitigate transformer aging. The nature of transformer loads is changing with the integration of distributed energy resources (DERs) and electric vehicles (EVs). This paper first reviews factors that influence the aging of distribution transformers, including root causes of transformer failure. Existing and proposed load control methods are then discussed. A distribution model is introduced to help evaluate potential control methods.

Exploring the contexts of urban science classrooms: Cogenerative dialogues, coteaching, and cosmopolitanism

NASA Astrophysics Data System (ADS)

Emdin, Christopher

The body of work presented in this dissertation is a response to the reported association between poor outcomes in science achievement and students of color in urban schools. By presenting counterexamples to the cultural motif that urban students of color perform poorly in science, I argue that poor achievement cannot be traced to a group of people but can be linked to institutions promoting subject delivery methods that instill distaste for science and compel students to display an illusion of disinterest in school. There are two major goals of this study. First, I plan to demonstrate how plans of action generated by coteachers and cogenerative dialogue groups can coalesce under the ethos of making science and schooling accessible to populations that are traditionally marginalized from science achievement. My second aim is to develop mechanisms for transforming science learning contexts into cosmopolitan learning communities that develop student success in science. Through a three-year ethnographic study of physics and chemistry classrooms in a high school in New York City, I present explorations of the culture and context of the urban classroom as a chief means to meet my goals. In my research, I find that obstacles to identity development around science can be tied to corporate understandings of teaching and learning that are amenable to local efforts toward change. This change is facilitated through the use of transformative tools like cogenerative dialogues, coteaching, and cosmopolitanism. Through the application of these research tools, I uncover and investigate how various misalignments that present themselves in physics and chemistry classrooms serve as signifiers of macro issues that permeate science classrooms from larger fields. By utilizing cogenerative dialogues as a tool for investigating both micro enactments within classrooms and the macro structures that generate these enactments, I show how students and teachers can work together as co-researchers and coteachers that engage in a dual process of questioning existent structures that do not support science success and transforming them.

A simple and reliable multi-gene transformation method for switchgrass.

PubMed

Ogawa, Yoichi; Shirakawa, Makoto; Koumoto, Yasuko; Honda, Masaho; Asami, Yuki; Kondo, Yasuhiro; Hara-Nishimura, Ikuko

2014-07-01

A simple and reliable Agrobacterium -mediated transformation method was developed for switchgrass. Using this method, many transgenic plants carrying multiple genes-of-interest could be produced without untransformed escape. Switchgrass (Panicum virgatum L.) is a promising biomass crop for bioenergy. To obtain transgenic switchgrass plants carrying a multi-gene trait in a simple manner, an Agrobacterium-mediated transformation method was established by constructing a Gateway-based binary vector, optimizing transformation conditions and developing a novel selection method. A MultiRound Gateway-compatible destination binary vector carrying the bar selectable marker gene, pHKGB110, was constructed to introduce multiple genes of interest in a single transformation. Two reporter gene expression cassettes, GUSPlus and gfp, were constructed independently on two entry vectors and then introduced into a single T-DNA region of pHKGB110 via sequential LR reactions. Agrobacterium tumefaciens EHA101 carrying the resultant binary vector pHKGB112 and caryopsis-derived compact embryogenic calli were used for transformation experiments. Prolonged cocultivation for 7 days followed by cultivation on media containing meropenem improved transformation efficiency without overgrowth of Agrobacterium, which was, however, not inhibited by cefotaxime or Timentin. In addition, untransformed escape shoots were completely eliminated during the rooting stage by direct dipping the putatively transformed shoots into the herbicide Basta solution for a few seconds, designated as the 'herbicide dipping method'. It was also demonstrated that more than 90 % of the bar-positive transformants carried both reporters delivered from pHKGB112. This simple and reliable transformation method, which incorporates a new selection technique and the use of a MultiRound Gateway-based binary vector, would be suitable for producing a large number of transgenic lines carrying multiple genes.

Comparison of algorithms for computing the two-dimensional discrete Hartley transform

NASA Technical Reports Server (NTRS)

Reichenbach, Stephen E.; Burton, John C.; Miller, Keith W.

1989-01-01

Three methods have been described for computing the two-dimensional discrete Hartley transform. Two of these employ a separable transform, the third method, the vector-radix algorithm, does not require separability. In-place computation of the vector-radix method is described. Operation counts and execution times indicate that the vector-radix method is fastest.

Through The Decades - Changes in Social, Economic, Legal and Planning Determinants of Residential Development across Decades - Evidence from Suburban Areas in Poland

NASA Astrophysics Data System (ADS)

Źróbek-Różańska, Alina; Zysk, Elżbieta; Źróbek, Ryszard

2017-10-01

Poland has experienced many political, legal, social and economic transformations. For the last twelve decades, this country was under foreign partition, in the war, under the influence of socialist system with centrally planned economy and finally regained autonomy and rapidly introduced market economy. Each epoch had its own characteristic, that can be recognized also in the residential buildings development. Therefore, the authors focused on the social, economic, legal and planning conditionings that shaped the development of the residential buildings with the most characteristic periods: pre-II world war, 50-ties, 60-ties, 70-ties, 80-ties, 90-ties and XXI century. Some of them are visible in the still existing residential buildings, especially in the suburban villages. The most recent process that can be observed in the study area is urban sprawl. Since the beginning of the XXI century, urban population in Poland has been gradually declining, while suburban villages transform into ‘urban-like’ districts. The aim of the study was to arrange and present in the decade-by-decade manner, the social, economic, legal and planning conditionings that were valid in particular periods. It was realized by correlating information on the contemporary social trends, economic conditions, legal framework and planning regulations. Presentation was enriched by the examples of the buildings developed in the accordance with the contemporary restrictions.

Clinical trials recruitment planning: A proposed framework from the Clinical Trials Transformation Initiative.

PubMed

Huang, Grant D; Bull, Jonca; Johnston McKee, Kelly; Mahon, Elizabeth; Harper, Beth; Roberts, Jamie N

2018-03-01

Patient recruitment is widely recognized as a key determinant of success for clinical trials. Yet a substantial number of trials fail to reach recruitment goals-a situation that has important scientific, financial, ethical, and policy implications. Further, there are important effects on stakeholders who directly contribute to the trial including investigators, sponsors, and study participants. Despite efforts over multiple decades to identify and address barriers, recruitment challenges persist. To advance a more comprehensive approach to trial recruitment, the Clinical Trials Transformation Initiative (CTTI) convened a project team to examine the challenges and to issue actionable, evidence-based recommendations for improving recruitment planning that extend beyond common study-specific strategies. We describe our multi-stakeholder effort to develop a framework that delineates three areas essential to strategic recruitment planning efforts: (1) trial design and protocol development, (2) trial feasibility and site selection, and (3) communication. Our recommendations propose an upstream approach to recruitment planning that has the potential to produce greater impact and reduce downstream barriers. Additionally, we offer tools to help facilitate adoption of the recommendations. We hope that our framework and recommendations will serve as a guide for initial efforts in clinical trial recruitment planning irrespective of disease or intervention focus, provide a common basis for discussions in this area and generate targets for further analysis and continual improvement. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

Realigning Resources for District Transformation: Using American Recovery and Reinvestment Act Funds to Advance a Strategic Education Reform Agenda

ERIC Educational Resources Information Center

Education Resource Strategies, 2009

2009-01-01

School districts and states have begun to receive education funds doled out from the American Recovery and Reinvestment Act, or ARRA, and many have a simple plan for the money--prevent teacher layoffs and restore current programs that were heading for the chopping block. This plan aligns with the legislation's intent to address the acute financial…

Progressive Era Industry and Its Legacy: Essays and Lesson Plans for Teaching Industrial History of the Progressive Era.

ERIC Educational Resources Information Center

Murray, William J., Ed.

The Progressive Era, roughly the period between the Spanish American War and the U.S. entry into World War I, was a period of transformation, a time when the United States ceased being predominantly an agricultural economy with a minor industrial base and became predominantly a modern industrialized nation. These essays and lesson plans, the…

Virtual Team E-Leadership: The Effects of Leadership Style and Conflict Management Mode on the Online Learning Performance of Students in a Business-Planning Course

ERIC Educational Resources Information Center

Chang, Wen-Long; Lee, Chun-Yi

2013-01-01

The aim of this study was to investigate the influence of leadership style, whether transactional or transformational, and conflict management mode on the online learning performance of students in a business-planning course. Conflict management was performed using the following five approaches: (1) avoidance, (2) accommodation, (3) competition,…

Enhancing the Sense of Community and Learning Experience Using Self-Paced Instruction and Peer Tutoring in a Computer-Laboratory Course

ERIC Educational Resources Information Center

Buraphadeja, Vasa; Kumnuanta, Jirang

2011-01-01

In its second decade of education reform and its third cycle of national ICT master plans, Thailand struggles to transform its aspirations into practice. This paper chronicles three decades of Thailand's ICT national plans and their relation to education reform. It also discusses the effect of global trends, Asian cultures, and Thai cultures on…

Work plan for determining the occurrence of glyphosate, its transformation product AMPA, other herbicide compounds, and antibiotics in midwestern United States streams, 2002

USGS Publications Warehouse

Battaglin, W.A.; Thurman, E.M.; Kolpin, D.W.; Scribner, E.A.; Sandstrom, M.W.; Kuivila, K.M.

2003-01-01

The objective of this study is to determine the distribution of glyphosate and its primary transformation product aminomethylphosphonic acid (AMPA) in midwestern streams during post-application and harvest-season runoff events. Water samples will be collected in 2002 during two post-herbicide-application runoff events and one harvest-season runoff event from 53 sites on streams in the Midwestern United States. All samples will be analyzed at the U.S. Geological Survey Organic Geochemistry Research Laboratory in Lawrence, Kansas, for glyphosate and 20 other herbicides. Samples will also be analyzed for a glyphosate transformation product (AMPA) and 26 other herbicide transformation products, using GC/MS or HPLC/MS. Selected samples will be analyzed for 36 antibiotics or antibiotic transformational products. Results from this study will represent the first broad-scale investigation of glyphosate and AMPA in U.S. water resources.

An algorithmic interactive planning framework in support of sustainable technologies

NASA Astrophysics Data System (ADS)

Prica, Marija D.

This thesis addresses the difficult problem of generation expansion planning that employs the most effective technologies in today's changing electric energy industry. The electrical energy industry, in both the industrialized world and in developing countries, is experiencing transformation in a number of different ways. This transformation is driven by major technological breakthroughs (such as the influx of unconventional smaller-scale resources), by industry restructuring, changing environmental objectives, and the ultimate threat of resource scarcity. This thesis proposes a possible planning framework in support of sustainable technologies where sustainability is viewed as a mix of multiple attributes ranging from reliability and environmental impact to short- and long-term efficiency. The idea of centralized peak-load pricing, which accounts for the tradeoffs between cumulative operational effects and the cost of new investments, is the key concept in support of long-term planning in the changing industry. To start with, an interactive planning framework for generation expansion is posed as a distributed decision-making model. In order to reconcile the distributed sub-objectives of different decision makers with system-wide sustainability objectives, a new concept of distributed interactive peak load pricing is proposed. To be able to make the right decisions, the decision makers must have sufficient information about the estimated long-term electricity prices. The sub-objectives of power plant owners and load-serving entities are profit maximization. Optimized long-term expansion plans based on predicted electricity prices are communicated to the system-wide planning authority as long-run bids. The long-term expansion bids are cleared by the coordinating planner so that the system-wide long-term performance criteria are satisfied. The interactions between generation owners and the coordinating planning authority are repeated annually. We view the proposed interactive planning framework as a necessary paradigm for planning in the changing industry where choice must be reconciled with societal public objectives.

Comparing transformation methods for DNA microarray data

PubMed Central

Thygesen, Helene H; Zwinderman, Aeilko H

2004-01-01

Background When DNA microarray data are used for gene clustering, genotype/phenotype correlation studies, or tissue classification the signal intensities are usually transformed and normalized in several steps in order to improve comparability and signal/noise ratio. These steps may include subtraction of an estimated background signal, subtracting the reference signal, smoothing (to account for nonlinear measurement effects), and more. Different authors use different approaches, and it is generally not clear to users which method they should prefer. Results We used the ratio between biological variance and measurement variance (which is an F-like statistic) as a quality measure for transformation methods, and we demonstrate a method for maximizing that variance ratio on real data. We explore a number of transformations issues, including Box-Cox transformation, baseline shift, partial subtraction of the log-reference signal and smoothing. It appears that the optimal choice of parameters for the transformation methods depends on the data. Further, the behavior of the variance ratio, under the null hypothesis of zero biological variance, appears to depend on the choice of parameters. Conclusions The use of replicates in microarray experiments is important. Adjustment for the null-hypothesis behavior of the variance ratio is critical to the selection of transformation method. PMID:15202953

Comparing transformation methods for DNA microarray data.

PubMed

Thygesen, Helene H; Zwinderman, Aeilko H

2004-06-17

When DNA microarray data are used for gene clustering, genotype/phenotype correlation studies, or tissue classification the signal intensities are usually transformed and normalized in several steps in order to improve comparability and signal/noise ratio. These steps may include subtraction of an estimated background signal, subtracting the reference signal, smoothing (to account for nonlinear measurement effects), and more. Different authors use different approaches, and it is generally not clear to users which method they should prefer. We used the ratio between biological variance and measurement variance (which is an F-like statistic) as a quality measure for transformation methods, and we demonstrate a method for maximizing that variance ratio on real data. We explore a number of transformations issues, including Box-Cox transformation, baseline shift, partial subtraction of the log-reference signal and smoothing. It appears that the optimal choice of parameters for the transformation methods depends on the data. Further, the behavior of the variance ratio, under the null hypothesis of zero biological variance, appears to depend on the choice of parameters. The use of replicates in microarray experiments is important. Adjustment for the null-hypothesis behavior of the variance ratio is critical to the selection of transformation method.

A 4D-optimization concept for scanned ion beam therapy.

PubMed

Graeff, Christian; Lüchtenborg, Robert; Eley, John Gordon; Durante, Marco; Bert, Christoph

2013-12-01

Scanned carbon beam therapy offers advantageous dose distributions and an increased biological effect. Treating moving targets is complex due to sensitivity to range changes and interplay. We propose a 4D treatment planning concept that considers motion during particle number optimization. The target was subdivided into sectors, one for each motion phase of a 4D-CT. Each sector was non-rigidly transformed to its motion phase and there targeted by a dedicated raster field (RST). Therefore, the resulting 4D-RST compensated target motion and range changes. A 4D treatment control system (TCS) was needed for synchronized delivery to the measured patient motion. 4D-optimized plans were simulated for 9 NSCLC lung cancer patients and compared to static irradiation at end-exhale. A prototype TCS was implemented and successfully tested in a film experiment. The 4D-optimized treatment plan resulted in only slightly lower dose coverage of the target compared to static optimization, with V 95% of 97.9% (median, range 96.5-99.4%) vs. 99.3% (98.5-99.8%), with negligible overdose. The conformity number was comparable at 88.2% (85.1-92.5%) vs. 85.2% (79.9-91.2%) for 4D and static, respectively. We implemented and tested a 4D treatment plan optimization method resulting in highly conformal dose delivery. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

A patient-centered longitudinal care plan: vision versus reality

PubMed Central

Dykes, Patricia C; Samal, Lipika; Donahue, Moreen; Greenberg, Jeffrey O; Hurley, Ann C; Hasan, Omar; O'Malley, Terrance A; Venkatesh, Arjun K; Volk, Lynn A; Bates, David W

2014-01-01

Objective As healthcare systems and providers move toward meaningful use of electronic health records, longitudinal care plans (LCPs) may provide a means to improve communication and coordination as patients transition across settings. The objective of this study was to determine the current state of communication of LCPs across settings and levels of care. Materials and methods We conducted surveys and interviews with professionals from emergency departments, acute care hospitals, skilled nursing facilities, and home health agency settings in six regions in the USA. We coded the transcripts according to the Agency for Healthcare Research and Quality (AHRQ) ‘Broad Approaches’ to care coordination to understand the degree to which current practice meets the definition of an LCP. Results Participants (n=22) from all settings reported that LCPs do not exist in their current state. We found LCPs in practice, and none of these were shared or reconciled across settings. Moreover, we found wide variation in the types and formats of care plan information that was communicated as patients transitioned. The most common formats, even when care plan information was communicated within the same healthcare system, were paper and fax. Discussion These findings have implications for data reuse, interoperability, and achieving widespread adoption of LCPs. Conclusions The use of LCPs to support care transitions is suboptimal. Strategies are needed to transform the LCP from vision to reality. PMID:24996874

Comparison of Dose Decrement from Intrafraction Motion for Prone and Supine Prostate Radiotherapy

PubMed Central

Olsen, Jeffrey; Parikh, Parag J; Watts, Michael; Noel, Camille E; Baker, Kenneth W; Santanam, Lakshmi; Michalski, Jeff M

2012-01-01

Background and Purpose Dose effects of intrafraction motion during prone prostate radiotherapy are unknown. We compared prone and supine treatment using real-time tracking data to model dose coverage. Material and Methods Electromagnetic tracking data was analyzed for 10 patients treated prone, and 15 treated supine, with IMRT for localized prostate cancer. Plans were generated using 0, 3, and 5 mm PTV expansions. Manual beam-hold interventions were applied to reposition the patient when translations exceeded a predetermined threshold. A custom software application (SWIFTER) used intrafraction tracking data acquired during beam-on to model delivered prostate dose, by applying rigid body transformations to the prostate structure contoured at simulation within the planned dose cloud. The delivered minimum prostate dose as a percentage of planned dose (Dmin%), and prostate volume covered by the prescription dose as a percentage of the planned volume (VRx%) were compared for prone and supine treatment. Results Dmin% was reduced for prone treatment for 0 (p=0.02) and 3 mm (p=0.03) PTV margins. VRx% was reduced for prone treatment only for 0 mm margins (p=0.002). No significant differences were found using 5 mm margins. Conclusions Intrafraction motion has a greater impact on target coverage for prone compared to supine prostate radiotherapy. PTV margins of 3 mm or less correlate with a significant decrease in delivered dose for prone treatment. PMID:22809590

Computer-aided surgical planner for a new bone deformity correction device using axis-angle representation.

PubMed

Wu, Ying Ying; Plakseychuk, Anton; Shimada, Kenji

2014-11-01

Current external fixators for distraction osteogenesis (DO) are unable to correct all types of deformities in the lower limb and are difficult to use because of the lack of a pre-surgical planning system. We propose a DO system that consists of a surgical planner and a new, easy-to-setup unilateral fixator that not only corrects all lower limb deformity, but also generates the contralateral/predefined bone shape. Conventionally, bulky constructs with six or more joints (six degrees of freedom, 6DOF) are needed to correct a 3D deformity. By applying the axis-angle representation, we can achieve that with a compact construct with only two joints (2DOF). The proposed system makes use of computer-aided design software and computational methods to plan and simulate the planned procedure. Results of our stress analysis suggest that the stiffness of our proposed fixator is comparable to that of the Orthofix unilateral external fixator. We tested the surgical system on a model of an adult deformed tibia and the resulting bone trajectory deviates from the target bone trajectory by 1.8mm, which is below our defined threshold error of 2mm. We also extracted the transformation matrix that defines the deformity from the bone model and simulated the planned procedure. Copyright © 2014 IPEM. Published by Elsevier Ltd. All rights reserved.

Genetic transformation protocols using zygotic embryos as explants: an overview.

PubMed

Tahir, Muhammad; Waraich, Ejaz A; Stasolla, Claudio

2011-01-01

Genetic transformation of plants is an innovative research tool which has practical significance for the development of new and improved genotypes or cultivars. However, stable introduction of genes of interest into nuclear genomes depends on several factors such as the choice of target tissue, the method of DNA delivery in the target tissue, and the appropriate method to select the transformed plants. Mature or immature zygotic embryos have been a popular choice as explant or target tissue for genetic transformation in both angiosperms and gymnosperms. As a result, considerable protocols have emerged in the literature which have been optimized for various plant species in terms of transformation methods and selection procedures for transformed plants. This article summarizes the recent advances in plant transformation using zygotic embryos as explants.

A fuzzy feature fusion method for auto-segmentation of gliomas with multi-modality diffusion and perfusion magnetic resonance images in radiotherapy.

PubMed

Guo, Lu; Wang, Ping; Sun, Ranran; Yang, Chengwen; Zhang, Ning; Guo, Yu; Feng, Yuanming

2018-02-19

The diffusion and perfusion magnetic resonance (MR) images can provide functional information about tumour and enable more sensitive detection of the tumour extent. We aimed to develop a fuzzy feature fusion method for auto-segmentation of gliomas in radiotherapy planning using multi-parametric functional MR images including apparent diffusion coefficient (ADC), fractional anisotropy (FA) and relative cerebral blood volume (rCBV). For each functional modality, one histogram-based fuzzy model was created to transform image volume into a fuzzy feature space. Based on the fuzzy fusion result of the three fuzzy feature spaces, regions with high possibility belonging to tumour were generated automatically. The auto-segmentations of tumour in structural MR images were added in final auto-segmented gross tumour volume (GTV). For evaluation, one radiation oncologist delineated GTVs for nine patients with all modalities. Comparisons between manually delineated and auto-segmented GTVs showed that, the mean volume difference was 8.69% (±5.62%); the mean Dice's similarity coefficient (DSC) was 0.88 (±0.02); the mean sensitivity and specificity of auto-segmentation was 0.87 (±0.04) and 0.98 (±0.01) respectively. High accuracy and efficiency can be achieved with the new method, which shows potential of utilizing functional multi-parametric MR images for target definition in precision radiation treatment planning for patients with gliomas.

Interactive approach to segment organs at risk in radiotherapy treatment planning

NASA Astrophysics Data System (ADS)

Dolz, Jose; Kirisli, Hortense A.; Viard, Romain; Massoptier, Laurent

2014-03-01

Accurate delineation of organs at risk (OAR) is required for radiation treatment planning (RTP). However, it is a very time consuming and tedious task. The use in clinic of image guided radiation therapy (IGRT) becomes more and more popular, thus increasing the need of (semi-)automatic methods for delineation of the OAR. In this work, an interactive segmentation approach to delineate OAR is proposed and validated. The method is based on the combination of watershed transformation, which groups small areas of similar intensities in homogeneous labels, and graph cuts approach, which uses these labels to create the graph. Segmentation information can be added in any view - axial, sagittal or coronal -, making the interaction with the algorithm easy and fast. Subsequently, this information is propagated within the whole volume, providing a spatially coherent result. Manual delineations made by experts of 6 OAR - lungs, kidneys, liver, spleen, heart and aorta - over a set of 9 computed tomography (CT) scans were used as reference standard to validate the proposed approach. With a maximum of 4 interactions, a Dice similarity coefficient (DSC) higher than 0.87 was obtained, which demonstrates that, with the proposed segmentation approach, only few interactions are required to achieve similar results as the ones obtained manually. The integration of this method in the RTP process may save a considerable amount of time, and reduce the annotation complexity.

Soybean (Glycine max) transformation using mature cotyledonary node explants.

PubMed

Olhoft, Paula M; Donovan, Christopher M; Somers, David A

2006-01-01

Agrobacterium tumefaciens-mediated transformation of soybeans has been steadily improved since its development in 1988. Soybean transformation is now possible in a range of genotypes from different maturity groups using different explants as sources of regenerable cells, various selectable marker genes and selective agents, and different A. tumefaciens strains. The cotyledonary-node method has been extensively investigated and across a number of laboratories yields on average greater than 1% transformation efficiency (one Southern-positive, independent event per 100 cotyledonary-node explants). Continued improvements in the cotyledonary-node method concomitant with further increases in transformation efficiency will enhance broader adoption of this already productive transformation method for use in crop improvement and functional genomics research efforts.

Fast Numerical Simulation of Focused Ultrasound Treatments During Respiratory Motion With Discontinuous Motion Boundaries.

PubMed

Schwenke, Michael; Georgii, Joachim; Preusser, Tobias

2017-07-01

Focused ultrasound (FUS) is rapidly gaining clinical acceptance for several target tissues in the human body. Yet, treating liver targets is not clinically applied due to a high complexity of the procedure (noninvasiveness, target motion, complex anatomy, blood cooling effects, shielding by ribs, and limited image-based monitoring). To reduce the complexity, numerical FUS simulations can be utilized for both treatment planning and execution. These use-cases demand highly accurate and computationally efficient simulations. We propose a numerical method for the simulation of abdominal FUS treatments during respiratory motion of the organs and target. Especially, a novel approach is proposed to simulate the heating during motion by solving Pennes' bioheat equation in a computational reference space, i.e., the equation is mathematically transformed to the reference. The approach allows for motion discontinuities, e.g., the sliding of the liver along the abdominal wall. Implementing the solver completely on the graphics processing unit and combining it with an atlas-based ultrasound simulation approach yields a simulation performance faster than real time (less than 50-s computing time for 100 s of treatment time) on a modern off-the-shelf laptop. The simulation method is incorporated into a treatment planning demonstration application that allows to simulate real patient cases including respiratory motion. The high performance of the presented simulation method opens the door to clinical applications. The methods bear the potential to enable the application of FUS for moving organs.

Strategic planning in healthcare organizations.

PubMed

Rodríguez Perera, Francisco de Paula; Peiró, Manel

2012-08-01

Strategic planning is a completely valid and useful tool for guiding all types of organizations, including healthcare organizations. The organizational level at which the strategic planning process is relevant depends on the unit's size, its complexity, and the differentiation of the service provided. A cardiology department, a hemodynamic unit, or an electrophysiology unit can be an appropriate level, as long as their plans align with other plans at higher levels. The leader of each unit is the person responsible for promoting the planning process, a core and essential part of his or her role. The process of strategic planning is programmable, systematic, rational, and holistic and integrates the short, medium, and long term, allowing the healthcare organization to focus on relevant and lasting transformations for the future. Copyright © 2012 Sociedad Española de Cardiología. Published by Elsevier Espana. All rights reserved.

Use of the Box-Cox Transformation in Detecting Changepoints in Daily Precipitation Data Series

NASA Astrophysics Data System (ADS)

Wang, X. L.; Chen, H.; Wu, Y.; Pu, Q.

2009-04-01

This study integrates a Box-Cox power transformation procedure into two statistical tests for detecting changepoints in Gaussian data series, to make the changepoint detection methods applicable to non-Gaussian data series, such as daily precipitation amounts. The detection power aspects of transformed methods in a common trend two-phase regression setting are assessed by Monte Carlo simulations for data of a log-normal or Gamma distribution. The results show that the transformed methods have increased the power of detection, in comparison with the corresponding original (untransformed) methods. The transformed data much better approximate to a Gaussian distribution. As an example of application, the new methods are applied to a series of daily precipitation amounts recorded at a station in Canada, showing satisfactory detection power.

New method for the transformation of solar radiation energy into electric power for energy feeding of the space vehicles

NASA Astrophysics Data System (ADS)

Ludanov, K. I.

The author proposes a new method for the transformation of solar radiation energy into electric power, which is alternative for photo-transformation. Ukrpatents's positive decisions are obtained for the method and for the installation for its realization. The method includes two phases: concentration of solar radiation by paraboloid mirrors with high potential heat obtaining in the helio receiver and the next heat transformation into electric power in the framework of the thermal cycle "high temperature electrolytic steam decomposition on the components (H2 and O2) + electrochemical generation by the way of the water recombination from H2 and O2 in the low temperature fuel cell". The new method gives the double superiority in comparison with the photo-transformation.

36 CFR 910.11 - Comprehensive urban planning and design.

Code of Federal Regulations, 2010 CFR

2010-07-01

... to accommodate the requirements and needs of historic preservation, affirmative action, business... along Pennsylvania Avenue shall be designed so as to support the transformation of the Avenue into an...

Analysis of temperature rise for piezoelectric transformer using finite-element method.

PubMed

Joo, Hyun-Woo; Lee, Chang-Hwan; Rho, Jong-Seok; Jung, Hyun-Kyo

2006-08-01

Analysis of heat problem and temperature field of a piezoelectric transformer, operated at steady-state conditions, is described. The resonance frequency of the transformer is calculated from impedance and electrical gain analysis using a finite-element method. Mechanical displacement and electric potential of the transformer at the calculated resonance frequency are used to calculate the loss distribution of the transformer. Temperature distribution using discretized heat transfer equation is calculated from the obtained losses of the transformer. Properties of the piezoelectric material, dependent on the temperature field, are measured to recalculate the losses, temperature distribution, and new resonance characteristics of the transformer. Iterative method is adopted to recalculate the losses and resonance frequency due to the changes of the material constants from temperature increase. Computed temperature distributions and new resonance characteristics of the transformer at steady-state temperature are verified by comparison with experimental results.

Fast heap transform-based QR-decomposition of real and complex matrices: algorithms and codes

NASA Astrophysics Data System (ADS)

Grigoryan, Artyom M.

2015-03-01

In this paper, we describe a new look on the application of Givens rotations to the QR-decomposition problem, which is similar to the method of Householder transformations. We apply the concept of the discrete heap transform, or signal-induced unitary transforms which had been introduced by Grigoryan (2006) and used in signal and image processing. Both cases of real and complex nonsingular matrices are considered and examples of performing QR-decomposition of square matrices are given. The proposed method of QR-decomposition for the complex matrix is novel and differs from the known method of complex Givens rotation and is based on analytical equations for the heap transforms. Many examples illustrated the proposed heap transform method of QR-decomposition are given, algorithms are described in detail, and MATLAB-based codes are included.

Reducing aberration effect of Fourier transform lens by modifying Fourier spectrum of diffractive optical element in beam shaping optical system.

PubMed

Zhang, Fang; Zhu, Jing; Song, Qiang; Yue, Weirui; Liu, Jingdan; Wang, Jian; Situ, Guohai; Huang, Huijie

2015-10-20

In general, Fourier transform lenses are considered as ideal in the design algorithms of diffractive optical elements (DOEs). However, the inherent aberrations of a real Fourier transform lens disturb the far field pattern. The difference between the generated pattern and the expected design will impact the system performance. Therefore, a method for modifying the Fourier spectrum of DOEs without introducing other optical elements to reduce the aberration effect of the Fourier transform lens is proposed. By applying this method, beam shaping performance is improved markedly for the optical system with a real Fourier transform lens. The experiments carried out with a commercial Fourier transform lens give evidence for this method. The method is capable of reducing the system complexity as well as improving its performance.

Study and development of techniques for automatic control of remote manipulators

NASA Technical Reports Server (NTRS)

Shaket, E.; Leal, A.

1976-01-01

An overall conceptual design for an autonomous control system of remote manipulators which utilizes feedback was constructed. The system consists of a description of the high-level capabilities of a model from which design algorithms are constructed. The autonomous capability is achieved through automatic planning and locally controlled execution of the plans. The operator gives his commands in high level task-oriented terms. The system transforms these commands into a plan. It uses built-in procedural knowledge of the problem domain and an internal model of the current state of the world.

Sweet Potato [Ipomoea batatas (L.) Lam].

PubMed

Song, Guo-qing; Yamaguchi, Ken-ichi

2006-01-01

Among the available transformation methods reported on sweet potato, Agrobacterium tumefaciens-mediated transformation is more successful and desirable. Stem explants have shown to be ideal for the transformation of sweet potato because of their ready availability as explants, the simple transformation process, and high-frequency-regeneration via somatic embryogenesis. Under the two-step kanamycin-hygromycin selection method and using the appropriate explants type (stem explants), the efficiency of transformation can be considerably improved in cv. Beniazuma. The high efficiency in the transformation of stem explants suggests that the transformation protocol described in this chapter warrants testing for routine stable transformation of diverse varieties of sweet potato.

The Roles of System and Organizational Leadership in System-Wide Evidence-Based Intervention Sustainment: A Mixed-Method Study.

PubMed

Aarons, Gregory A; Green, Amy E; Trott, Elise; Willging, Cathleen E; Torres, Elisa M; Ehrhart, Mark G; Roesch, Scott C

2016-11-01

If evidence-based interventions (EBIs) are not sustained, investments are wasted and public health impact is limited. Leadership has been suggested as a key determinant of implementation and sustainment; however, little empirical work has examined this factor. This mixed-methods study framed using the Exploration, Preparation, Implementation, Sustainment (EPIS) conceptual framework examines leadership in both the outer service system context and inner organizational context in eleven system-wide implementations of the same EBI across two U.S. states and 87 counties. Quantitative data at the outer context (i.e., system) and inner context (i.e., team) levels demonstrated that leadership predicted future sustainment and differentiated between sites with full, partial, or no sustainment. In the outer context positive sustainment leadership was characterized as establishing a project's mission and vision, early and continued planning for sustainment, realistic project plans, and having alternative strategies for project survival. Inner context frontline transformational leadership predicted sustainment while passive-avoidant leadership predicted non-sustainment. Qualitative results found that sustainment was associated with outer context leadership characterized by engagement in ongoing supportive EBI championing, marketing to stakeholders; persevering in these activities; taking action to institutionalize the EBI with funding, contracting, and system improvement plans; and fostering ongoing collaboration between stakeholders at state and county, and community stakeholder levels. For frontline leadership the most important activities included championing the EBI and providing practical support for service providers. There was both convergence and expansion that identified unique contributions of the quantitative and qualitative methods. Greater attention to leadership in both the outer system and inner organizational contexts is warranted to enhance EBI implementation and sustainment.

The Roles of System and Organizational Leadership in System-Wide Evidence-Based Intervention Sustainment: A Mixed-Method Study

PubMed Central

Aarons, Gregory A.; Green, Amy E.; Trott, Elise; Willging, Cathleen E.; Torres, Elisa M.; Ehrhart, Mark G.; Roesch, Scott C.

2017-01-01

If evidence-based interventions (EBIs) are not sustained, investments are wasted and public health impact is limited. Leadership has been suggested as a key determinant of implementation and sustainment; however, little empirical work has examined this factor. This mixed-methods study framed using the Exploration, Preparation, Implementation, Sustainment (EPIS) conceptual framework examines leadership in both the outer service system context and inner organizational context in eleven system-wide implementations of the same EBI across two U.S. states and 87 counties. Quantitative data at the outer context (i.e., system) and inner context (i.e., team) levels demonstrated that leadership predicted future sustainment and differentiated between sites with full, partial, or no sustainment. In the outer context positive sustainment leadership was characterized as establishing a project’s mission and vision, early and continued planning for sustainment, realistic project plans, and having alternative strategies for project survival. Inner context frontline transformational leadership predicted sustainment while passive-avoidant leadership predicted non-sustainment. Qualitative results found that sustainment was associated with outer context leadership characterized by engagement in ongoing supportive EBI championing, marketing to stakeholders; persevering in these activities; taking action to institutionalize the EBI with funding, contracting, and system improvement plans; and fostering ongoing collaboration between stakeholders at state and county, and community stakeholder levels. For frontline leadership the most important activities included championing the EBI and providing practical support for service providers. There was both convergence and expansion that identified unique contributions of the quantitative and qualitative methods. Greater attention to leadership in both the outer system and inner organizational contexts is warranted to enhance EBI implementation and sustainment. PMID:27439504

Sizing Firefighters: Method and Implications

PubMed Central

Hsiao, Hongwei; Whitestone, Jennifer; Kau, Tsui-Ying; Whisler, Richard; Routley, J. Gordon; Wilbur, Michael

2015-01-01

Objective This article reports new anthropometric information of U.S. firefighters for fire apparatus design applications (Study 1) and presents a data method to assist in firefighter anthropometric data usage for research-to-practice propositions (Study 2). Background Up-to-date anthropometric information of the U.S. firefighter population is needed for updating ergonomic and safety specifications for fire apparatus. Method A stratified sampling plan of three-age by three-race/ethnicity combinations was used to collect anthropometric data of 863 male and 88 female firefighters across the U.S. regions; 71 anthropometric dimensions were measured (Study 1). Differences among original, weighted, and normality transformed data from Study 1 were compared to allowable observer errors (Study 2). Results On average, male firefighters were 9.8 kg heavier and female firefighters were 29 mm taller than their counterparts in the general U.S. population. They also have larger upper-body builds than those of the general U.S. population. The data in weighted, unweighted, and normality transformed modes were compatible among each other with a few exceptions. Conclusion The data obtained in this study provide the first available U.S. national firefighter anthropometric information for fire apparatus designs. The data represent the demographic characteristics of the current firefighter population and, except for a few dimensions, can be directly employed into fire apparatus design applications without major weighting or nonnormality concerns. Application The up-to-date firefighter anthropometric data and data method will benefit the design of future fire apparatus and protective equipment, such as seats, body restraints, cabs, gloves, and bunker gear. PMID:25141595

Engineering calculations for communications satellite systems planning

NASA Technical Reports Server (NTRS)

Reilly, C. H.; Levis, C. A.; Mount-Campbell, C.; Gonsalvez, D. J.; Wang, C. W.; Yamamura, Y.

1985-01-01

Computer-based techniques for optimizing communications-satellite orbit and frequency assignments are discussed. A gradient-search code was tested against a BSS scenario derived from the RARC-83 data. Improvement was obtained, but each iteration requires about 50 minutes of IBM-3081 CPU time. Gradient-search experiments on a small FSS test problem, consisting of a single service area served by 8 satellites, showed quickest convergence when the satellites were all initially placed near the center of the available orbital arc with moderate spacing. A transformation technique is proposed for investigating the surface topography of the objective function used in the gradient-search method. A new synthesis approach is based on transforming single-entry interference constraints into corresponding constraints on satellite spacings. These constraints are used with linear objective functions to formulate the co-channel orbital assignment task as a linear-programming (LP) problem or mixed integer programming (MIP) problem. Globally optimal solutions are always found with the MIP problems, but not necessarily with the LP problems. The MIP solutions can be used to evaluate the quality of the LP solutions. The initial results are very encouraging.

[Reflective portfolio: a proposal for teaching and learning geared on competencies].

PubMed

Cotta, Rosângela Minardi Mitre; da Costa, Glauce Dias; Mendonça, Erica Toledo

2013-06-01

This article seeks to analyze the experience of collective construction of portfolios as a teaching-learning method in the discipline of Health Policy, identifying the competencies developed by students. Qualitative research, whose collection and data processing were conducted by means of documental and thematic analysis of 34 portfolios. The "Learning to be" and "Learning to live and work together" competencies were considered according to the proposals of the UNESCO report for Education. The training of critical-reflexive individuals, provided by the portfolio, was particularly observed when students reported the transformation of the negative views that they had about the health care system - an inefficient and precarious policy - to a positive vision - policy which deals with the principles of equity, integrity and universality. This process of critical transformation is the result of the practice and use of communication skills, information management (search, selection, analysis and evaluation of information), leadership, cooperation and human relationships (teamwork, ethics and recognition of diversity), and personal competencies (time management, responsibility and planning), namely important skills in the training of professionals committed to the national health policy.

"The largest Lean transformation in the world": the implementation and evaluation of lean in Saskatchewan healthcare.

PubMed

Kinsman, Leigh; Rotter, Thomas; Stevenson, Katherine; Bath, Brenna; Goodridge, Donna; Harrison, Liz; Dobson, Roy; Sari, Nazmi; Jeffery, Cathy; Bourassa, Carrie; Westhorp, Gill

2014-01-01

The Saskatchewan Ministry of Health has committed to a multi-million dollar investment toward the implementation of Lean methodology across the province's healthcare system. Originating as a production line discipline (the Toyota Production System), Lean has evolved to encompass process improvements including inventory management, waste reduction and quality improvement techniques. With an initial focus on leadership, strategic alignment, training and the creation of a supportive infrastructure (Lean promotion offices), the goal in Saskatchewan is a whole health system transformation that produces "better health, better value, better care, and better teams." Given the scope and scale of the initiative and the commitment of resources, it is vital that a comprehensive, longitudinal evaluation plan be implemented to support ongoing decision-making and program design. The nature of the initiative also offers a unique opportunity to contribute to health quality improvement science by advancing our understanding of the implementation and evaluation of complex, large-scale healthcare interventions. The purpose of this article is to summarize the background to Lean in Saskatchewan and the proposed evaluation methods. Copyright © 2014 Longwoods Publishing.

[Study on Differential Optical Absorption Spectroscopy Data Processing Based on Chirp-Z Transformation].

PubMed

Zheng, Hai-ming; Li, Guang-jie; Wu, Hao

2015-06-01

Differential optical absorption spectroscopy (DOAS) is a commonly used atmospheric pollution monitoring method. Denoising of monitoring spectral data will improve the inversion accuracy. Fourier transform filtering method is effectively capable of filtering out the noise in the spectral data. But the algorithm itself can introduce errors. In this paper, a chirp-z transform method is put forward. By means of the local thinning of Fourier transform spectrum, it can retain the denoising effect of Fourier transform and compensate the error of the algorithm, which will further improve the inversion accuracy. The paper study on the concentration retrieving of SO2 and NO2. The results show that simple division causes bigger error and is not very stable. Chirp-z transform is proved to be more accurate than Fourier transform. Results of the frequency spectrum analysis show that Fourier transform cannot solve the distortion and weakening problems of characteristic absorption spectrum. Chirp-z transform shows ability in fine refactoring of specific frequency spectrum.

2-COLOR Pupil Imaging Method to Detect Stellar Oscillations

NASA Astrophysics Data System (ADS)

Costantino, Sigismondi; Alessandro, Cacciani; Mauro, Dolci; Stuart, Jeffries; Eric, Fossat; Ludovico, Cesario; Paolo, Rapex; Luca, Bertello; Ferenc, Varadi; Wolfgang, Finsterle

Stellar intensity oscillations from the ground are strongly affected by atmospheric noise. For solar-type stars even Antarctic scintillation noise is still overwhelming. We proposed and tested a differential method that images on the same CCD detector two-color pupils of the telescope in order to compensate for intensity sky fluctuations guiding and saturation problems. SOHO data reveal that our method has an efficiency of 70% respect to the absolute amplitude variations. Using two instruments at Dome C and South Pole we can further minimize atmospheric color noise with cross-spectrum methods. This way we also decrease the likelihood of gaps in the data string due to bad weather. Observationally while waiting for the South Pole/Dome-C sites we are carrying on tests from available telescopes and Big Bear Mt. Wilson Teramo Milano. On the data analysis side we use the Random Lag Singular Cross-Spectrum Analysis which eliminates noise from the observed signal better than traditional Fourier transform. This method is also well-suited for extracting common oscillatory components from two or more observations including their relative phases as we are planning to do

Sizing firefighters: method and implications.

PubMed

Hsiao, Hongwei; Whitestone, Jennifer; Kau, Tsui-Ying; Whisler, Richard; Routley, J Gordon; Wilbur, Michael

2014-08-01

This article reports new anthropometric information of U.S. firefighters for fire apparatus design applications (Study 1) and presents a data method to assist in firefighter anthropometric data usage for research-to-practice propositions (Study 2). Up-to-date anthropometric information of the U.S. firefighter population is needed for updating ergonomic and safety specifications for fire apparatus. A stratified sampling plan of three-age by three-race/ethnicity combinations was used to collect anthropometric data of 863 male and 88 female firefighters across the U.S. regions; 71 anthropometric dimensions were measured (Study I). Differences among original, weighted, and normality transformed data from Study 1 were compared to allowable observer errors (Study 2). On average, male firefighters were 9.8 kg heavier and female firefighters were 29 mm taller than their counterparts in the general U.S. population. They also have larger upper-body builds than those of the general U.S. population. The data in weighted, unweighted, and normality transformed modes were compatible among each other with a few exceptions. The data obtained in this study provide the first available U.S. national firefighter anthropometric information for fire apparatus designs. The data represent the demographic characteristics of the current firefighter population and, except for a few dimensions, can be directly employed into fire apparatus design applications without major weighting or nonnormality concerns. The up-to-date firefighter anthropometric data and data method will benefit the design of future fire apparatus and protective equipment, such as seats, body restraints, cabs, gloves, and bunker gear.

SU-G-JeP3-12: Use of Cone Beam CT and Deformable Image Registration for Assessing Geometrical and Dosimetric Variations During Lung Radiotherapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jurkovic, I; Stathakis, S; Markovic, M

Purpose: To assess the value of cone beam CT (CBCT) combined with deformable image registration in estimating the accuracy of the delivered treatment and the suitability of the applied target margins. Methods: Two patients with lung tumor were selected. Using their CT images intensity modulated radiation therapy (IMRT) treatment plans were developed to deliver 66Gy to the 95% of the PTV in 2Gy fractions. Using the Velocity AI software, the planning CT of each patient was registered with the fractional CBCT images that were obtained through the course of the treatment. After a CT to CBCT deformable image registration (DIR),more » the same fractional deformation matrix was used for the deformation of the planned dose distributions, as well as of all the contoured volumes, to each CBCT dataset. The dosimetric differences between the planning target volume (PTV) and various organs at risk (OARs) were recorded and compared. Results: CBCT data such as CTV volume change and PTV coverage was analyzed. There was a moderate relationship between volume changes and contouring method (automatic contouring using the DIR transformation vs. manual contouring on each CBCT) for patient #1 (r = 0.49), and a strong relationship for patient #2 (r = 0.83). The average PTV volume coverage from all the CBCT datasets was 91.2% for patient #1 and 95.6% for patient #2. Conclusion: Daily setup variations, tumor volume motion and lung deformation due to breathing yield differences in the actual delivered dose distributions versus the planned ones. The results presented indicate that these differences are apparent even with the use of daily IGRT. In certain fractions, the margins used seem to be insufficient to ensure acceptable lung tumor coverage. The observed differences notably depend on the tumor volume size and location. A larger cohort of patient is under investigation to verify those findings.« less

KSC-2014-2028

NASA Image and Video Library

2014-04-10

CAPE CANAVERAL, Fla. -- At the Kennedy Space Center in Florida, Trey Carlson, the spaceport's master planner, describes how the Center Planning and Development Directorate CPD is working to help transform Kennedy into a multi-user spaceport through partnerships and resource planning. The event was first of what is planned to be quarterly meetings between NASA's industry partners and representatives of Kennedy's CPD, Safety and Mission Assurance, International Space Station Ground Processing, Chief Financial officer and Ground Processing and Ground Systems Development and Operations directorates. Center Planning and Development is the “front door” for partnerships with NASA’s Kennedy Space Center. Kennedy is now developing the world’s premier spaceport for government and commercial space industries using comprehensive resource planning and partnerships. Photo credit: NASA/Daniel Casper

KSC-2014-2029

NASA Image and Video Library

2014-04-10

CAPE CANAVERAL, Fla. -- At the Kennedy Space Center in Florida, Trey Carlson, the spaceport's master planner, describes how the Center Planning and Development Directorate CPD is working to help transform Kennedy into a multi-user spaceport through partnerships and resource planning. The event was first of what is planned to be quarterly meetings between NASA's industry partners and representatives of Kennedy's CPD, Safety and Mission Assurance, International Space Station Ground Processing, Chief Financial officer and Ground Processing and Ground Systems Development and Operations directorates. Center Planning and Development is the “front door” for partnerships with NASA’s Kennedy Space Center. Kennedy is now developing the world’s premier spaceport for government and commercial space industries using comprehensive resource planning and partnerships. Photo credit: NASA/Daniel Casper

Planning policy, sustainability and housebuilder practices: The move into (and out of?) the redevelopment of previously developed land.

PubMed

Karadimitriou, Nikos

2013-05-01

This paper explores the transformations of the housebuilding industry under the policy requirement to build on previously developed land (PDL). This requirement was a key lever in promoting the sustainable urban development agenda of UK governments from the early 1990s to 2010 and has survived albeit somewhat relaxed and permutated in the latest National Planning Policy Framework (NPPF). The paper therefore looks at the way in which the policy push towards densification and mixed use affected housebuilders' business strategy and practices and their ability to cope with the 2007 downturn of the housing market and its aftermath. It also points out the eventual feedback of some of these practices into planning policy. Following the gradual shift of British urban policy focus towards sustainability which started in the early 1990s, new configurations of actors, new skills, strategies and approaches to managing risk emerged in property development and housebuilding. There were at least two ways in which housebuilders could have responded to the requirements of developing long term mixed use high density projects on PDL. One way was to develop new products and to employ practices and combinations of practices involving phasing, a flexible approach to planning applications and innovative production methods. Alternatively, they could approach PDL development as a temporary turn of policy or view mixed use high density schemes as a niche market to be explored without drastically overhauling the business model of the entire firm. These transformations of the UK housebuilding sector were unfolding during a long period of buoyancy in the housing market which came to an end in 2007. Very little is known both about how housebuilder strategies and production practices evolved during the boom years as well as about how these firms coped with the effects of the 2007 market downturn. The paper draws on published data (company annual reports, government statistics) and primary material (stakeholder interviews, planning applications, unpublished project specific information) to explore two different approaches that two major housebuilders (the Berkeley Group and George Wimpey - now Taylor Wimpey) followed during the boom years in response to the changing requirements, risks and uncertainties embedded in the residential development process. The recent turmoil in the property markets acted as an 'acid test' to business models and practices and not all firms survived it. What is more, the UK government is now embedding some of those business practices into policy, thus completing one loop in a co-evolving feedback spiral between planning policy and business strategy.

Planning policy, sustainability and housebuilder practices: The move into (and out of?) the redevelopment of previously developed land

PubMed Central

Karadimitriou, Nikos

2013-01-01

This paper explores the transformations of the housebuilding industry under the policy requirement to build on previously developed land (PDL). This requirement was a key lever in promoting the sustainable urban development agenda of UK governments from the early 1990s to 2010 and has survived albeit somewhat relaxed and permutated in the latest National Planning Policy Framework (NPPF). The paper therefore looks at the way in which the policy push towards densification and mixed use affected housebuilders’ business strategy and practices and their ability to cope with the 2007 downturn of the housing market and its aftermath. It also points out the eventual feedback of some of these practices into planning policy. Following the gradual shift of British urban policy focus towards sustainability which started in the early 1990s, new configurations of actors, new skills, strategies and approaches to managing risk emerged in property development and housebuilding. There were at least two ways in which housebuilders could have responded to the requirements of developing long term mixed use high density projects on PDL. One way was to develop new products and to employ practices and combinations of practices involving phasing, a flexible approach to planning applications and innovative production methods. Alternatively, they could approach PDL development as a temporary turn of policy or view mixed use high density schemes as a niche market to be explored without drastically overhauling the business model of the entire firm. These transformations of the UK housebuilding sector were unfolding during a long period of buoyancy in the housing market which came to an end in 2007. Very little is known both about how housebuilder strategies and production practices evolved during the boom years as well as about how these firms coped with the effects of the 2007 market downturn. The paper draws on published data (company annual reports, government statistics) and primary material (stakeholder interviews, planning applications, unpublished project specific information) to explore two different approaches that two major housebuilders (the Berkeley Group and George Wimpey – now Taylor Wimpey) followed during the boom years in response to the changing requirements, risks and uncertainties embedded in the residential development process. The recent turmoil in the property markets acted as an ‘acid test’ to business models and practices and not all firms survived it. What is more, the UK government is now embedding some of those business practices into policy, thus completing one loop in a co-evolving feedback spiral between planning policy and business strategy. PMID:23805023

Cotton transformation via pollen tube pathway.

PubMed

Wang, Min; Zhang, Baohong; Wang, Qinglian

2013-01-01

Although many gene transfer methods have been employed for successfully obtaining transgenic cotton, the major constraint in cotton improvement is the limitation of genotype because the majority of transgenic methods require plant regeneration from a single transformed cell which is limited by cotton tissue culture. Comparing with other plant species, it is difficult to induce plant regeneration from cotton; currently, only a limited number of cotton cultivars can be cultured for obtaining regenerated plants. Thus, development of a simple and genotype-independent genetic transformation method is particularly important for cotton community. In this chapter, we present a simple, cost-efficient, and genotype-independent cotton transformation method-pollen tube pathway-mediated transformation. This method uses pollen tube pathway to deliver transgene into cotton embryo sacs and then insert foreign genes into cotton genome. There are three major steps for pollen tube pathway-mediated genetic transformation, which include injection of -foreign genes into pollen tube, integration of foreign genes into plant genome, and selection of transgenic plants.

Poisson denoising on the sphere

NASA Astrophysics Data System (ADS)

Schmitt, J.; Starck, J. L.; Fadili, J.; Grenier, I.; Casandjian, J. M.

2009-08-01

In the scope of the Fermi mission, Poisson noise removal should improve data quality and make source detection easier. This paper presents a method for Poisson data denoising on sphere, called Multi-Scale Variance Stabilizing Transform on Sphere (MS-VSTS). This method is based on a Variance Stabilizing Transform (VST), a transform which aims to stabilize a Poisson data set such that each stabilized sample has an (asymptotically) constant variance. In addition, for the VST used in the method, the transformed data are asymptotically Gaussian. Thus, MS-VSTS consists in decomposing the data into a sparse multi-scale dictionary (wavelets, curvelets, ridgelets...), and then applying a VST on the coefficients in order to get quasi-Gaussian stabilized coefficients. In this present article, the used multi-scale transform is the Isotropic Undecimated Wavelet Transform. Then, hypothesis tests are made to detect significant coefficients, and the denoised image is reconstructed with an iterative method based on Hybrid Steepest Descent (HST). The method is tested on simulated Fermi data.

Progress of gas-insulated transformers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Togawa, Y.; Ikeda, M.; Toda, K.

The world`s first transformer was manufactured at Ganz in Hungary in 1885. Two years later in 1887 patents applications were made for about oil immersed transformers in the US. Since then, oil immersed types have predominated for medium- and large-capacity transformers, which are now giving way to gas insulated transformers in some areas. Behind such trends are plans to construct substations inside buildings or underground, because of the difficulty in acquiring land for substations in large cities where power demand is concentrated. Requirements are protection against accidents, compactness and overall economy. Total gas insulated substations combining GIS units and gasmore » insulated transformers these needs. Demand for gas insulated transformers has been increasing rapidly, particularly in Japan and Hong Kong. First, relatively small-capacity models below 20--30 MVA were put into practical use and today 275 kV, 300 MVa models are in use and 500kV, 1,500 MVA models are coming into use. Engineering is progressing very rapidly in these areas. This paper describes the design techniques and important maintenance techniques for the latest gas insulated transformers from 5,000 kVA to 300 MVA.« less

Reconstructing Information in Large-Scale Structure via Logarithmic Mapping

NASA Astrophysics Data System (ADS)

Szapudi, Istvan

We propose to develop a new method to extract information from large-scale structure data combining two-point statistics and non-linear transformations; before, this information was available only with substantially more complex higher-order statistical methods. Initially, most of the cosmological information in large-scale structure lies in two-point statistics. With non- linear evolution, some of that useful information leaks into higher-order statistics. The PI and group has shown in a series of theoretical investigations how that leakage occurs, and explained the Fisher information plateau at smaller scales. This plateau means that even as more modes are added to the measurement of the power spectrum, the total cumulative information (loosely speaking the inverse errorbar) is not increasing. Recently we have shown in Neyrinck et al. (2009, 2010) that a logarithmic (and a related Gaussianization or Box-Cox) transformation on the non-linear Dark Matter or galaxy field reconstructs a surprisingly large fraction of this missing Fisher information of the initial conditions. This was predicted by the earlier wave mechanical formulation of gravitational dynamics by Szapudi & Kaiser (2003). The present proposal is focused on working out the theoretical underpinning of the method to a point that it can be used in practice to analyze data. In particular, one needs to deal with the usual real-life issues of galaxy surveys, such as complex geometry, discrete sam- pling (Poisson or sub-Poisson noise), bias (linear, or non-linear, deterministic, or stochastic), redshift distortions, pro jection effects for 2D samples, and the effects of photometric redshift errors. We will develop methods for weak lensing and Sunyaev-Zeldovich power spectra as well, the latter specifically targetting Planck. In addition, we plan to investigate the question of residual higher- order information after the non-linear mapping, and possible applications for cosmology. Our aim will be to work out practical methods, with the ultimate goal of cosmological parameter estimation. We will quantify with standard MCMC and Fisher methods (including DETF Figure of merit when applicable) the efficiency of our estimators, comparing with the conventional method, that uses the un-transformed field. Preliminary results indicate that the increase for NASA's WFIRST in the DETF Figure of Merit would be 1.5-4.2 using a range of pessimistic to optimistic assumptions, respectively.

Sampling from a Discrete Distribution While Preserving Monotonicity.

DTIC Science & Technology

1982-02-01

in a table beforehand, this procedure, known as the inverse transform method, requires n storage spaces and EX comparisons on average, which may prove...limitations that deserve attention: a. In general, the alias method does not preserve a monotone relationship between U and X as does the inverse transform method...uses the inverse transform approach but with more information computed beforehand, as in the alias method. The proposed method is not new having been

Leader development transformation in the Army Nurse Corps.

PubMed

Funari, Tamara S; Ford, Kathleen; Schoneboom, Bruce A

2011-01-01

The Army Nurse (AN) Corps is undergoing a historic transformation. Under the leadership of its Chief, MG Patricia Horoho, the Corps developed and implemented the AN Campaign Plan to insure that the Corps has the right capability and capacity to meet the current and future needs of the US Army. This article describes the work conducted by the AN Corps Leadership Imperative Action Team (Leader IAT) to develop full-spectrum leaders for the future. The mission of the Leader IAT is derived from both the AN Campaign plan as well as the operational objectives defined in the AN balanced scorecard. As a result of the analysis conducted during preparation of the AN Campaign Plan, several key gaps were identified regarding the Army Nurse Corps' ability to match leadership talents with the diverse demands of current missions, as well as its adaptability and flexibility to be prepared for unknown future missions. This article also introduces the Leadership Capability Map and other initiatives implemented to ensure the development of full-spectrum leaders who will be effective in the future military healthcare environment.

A transformed path integral approach for solution of the Fokker-Planck equation

NASA Astrophysics Data System (ADS)

Subramaniam, Gnana M.; Vedula, Prakash

2017-10-01

A novel path integral (PI) based method for solution of the Fokker-Planck equation is presented. The proposed method, termed the transformed path integral (TPI) method, utilizes a new formulation for the underlying short-time propagator to perform the evolution of the probability density function (PDF) in a transformed computational domain where a more accurate representation of the PDF can be ensured. The new formulation, based on a dynamic transformation of the original state space with the statistics of the PDF as parameters, preserves the non-negativity of the PDF and incorporates short-time properties of the underlying stochastic process. New update equations for the state PDF in a transformed space and the parameters of the transformation (including mean and covariance) that better accommodate nonlinearities in drift and non-Gaussian behavior in distributions are proposed (based on properties of the SDE). Owing to the choice of transformation considered, the proposed method maps a fixed grid in transformed space to a dynamically adaptive grid in the original state space. The TPI method, in contrast to conventional methods such as Monte Carlo simulations and fixed grid approaches, is able to better represent the distributions (especially the tail information) and better address challenges in processes with large diffusion, large drift and large concentration of PDF. Additionally, in the proposed TPI method, error bounds on the probability in the computational domain can be obtained using the Chebyshev's inequality. The benefits of the TPI method over conventional methods are illustrated through simulations of linear and nonlinear drift processes in one-dimensional and multidimensional state spaces. The effects of spatial and temporal grid resolutions as well as that of the diffusion coefficient on the error in the PDF are also characterized.

Analytical Support to Defence Transformation (Le soutien analytique a la transformation de la Defense)

DTIC Science & Technology

2010-04-01

analytical community. 5.1 Towards a Common Understanding of CD&E and CD&E Project Management Recent developments within NATO have contributed to the... project management purposes it is useful to distinguish four phases [P 21]: a) Preparation, Initiation and Structuring; b) Concept Development Planning...examined in more detail below. While the NATO CD&E policy provides a benchmark for a comprehensive, disciplined management of CD&E projects , it may

Strategic plan for geriatrics and extended care in the veterans health administration: background, plan, and progress to date.

PubMed

Shay, Kenneth; Hyduke, Barbara; Burris, James F

2013-04-01

The leaders of Geriatrics and Extended Care (GEC) in the Veterans Health Administration (VHA) undertook a strategic planning process that led to approval in 2009 of a multidisciplinary, evidence-guided strategic plan. This article reviews the four goals contained in that plan and describes VHA's progress in addressing them. The goals included transforming the healthcare system to a veteran-centric approach, achieving universal access to a panel of services, ensuring that the Veterans Affair's (VA) healthcare workforce was adequately prepared to manage the needs of the growing elderly veteran population, and integrating continuous improvement into all care enhancements. There has been substantial progress in addressing all four goals. All VHA health care has undergone an extensive transformation to patient-centered care, has enriched the services it can offer caregivers of dependent veterans, and has instituted models to better integrate VA and non-VA cares and services. A range of successful models of geriatric care described in the professional literature has been adapted to VA environments to gauge suitability for broader implementation. An executive-level task force developed a three-pronged approach for enhancing the VA's geriatric workforce. The VHA's performance measurement approaches increasingly include incentives to enhance the quality of management of vulnerable elderly adults in primary care. The GEC strategic plan was intended to serve as a road map for keeping VHA aligned with an ambitious but important long-term vision for GEC services. Although no discrete set of resources was appropriated for fulfillment of the plan's recommendations, this initial report reflects substantial progress in addressing most of its goals. © 2013, Copyright the Authors Journal compilation © 2013, The American Geriatrics Society.

Improved FFT-based numerical inversion of Laplace transforms via fast Hartley transform algorithm

NASA Technical Reports Server (NTRS)

Hwang, Chyi; Lu, Ming-Jeng; Shieh, Leang S.

1991-01-01

The disadvantages of numerical inversion of the Laplace transform via the conventional fast Fourier transform (FFT) are identified and an improved method is presented to remedy them. The improved method is based on introducing a new integration step length Delta(omega) = pi/mT for trapezoidal-rule approximation of the Bromwich integral, in which a new parameter, m, is introduced for controlling the accuracy of the numerical integration. Naturally, this method leads to multiple sets of complex FFT computations. A new inversion formula is derived such that N equally spaced samples of the inverse Laplace transform function can be obtained by (m/2) + 1 sets of N-point complex FFT computations or by m sets of real fast Hartley transform (FHT) computations.

Civilian Human Capital Strategic Plan 2006-2010

DTIC Science & Technology

2006-07-01

operations.” “ In a reconfigured Total Force, a new balance of skills must be coupled with greater accessibility to people so that the right forces...Plan for transforming DoD training) and promoting work life balance opportunities. Never before have the challenges facing DoD been greater as it...recruitment, retention, development, worklife , and workforce management strategies and systems in closing mission critical competency gaps—ensuring the right

Fuel Cycle Technologies 2014 Achievement Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hong, Bonnie C.

2015-01-01

The Fuel Cycle Technologies (FCT) program supports the Department of Energy’s (DOE’s) mission to: “Enhance U.S. security and economic growth through transformative science, technology innovation, and market solutions to meet our energy, nuclear security, and environmental challenges.” Goal 1 of DOE’s Strategic Plan is to innovate energy technologies that enhance U.S. economic growth and job creation, energy security, and environmental quality. FCT does this by investing in advanced technologies that could transform the nuclear fuel cycle in the decades to come. Goal 2 of DOE’s Strategic Plan is to strengthen national security by strengthening key science, technology, and engineering capabilities.more » FCT does this by working closely with the National Nuclear Security Administration and the U.S Department of State to develop advanced technologies that support the Nation’s nuclear nonproliferation goals.« less

Technical Review of the Domestic Nuclear Detection Office Transformational and Applied Research Directorate’s Research and Development Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lavietes, Anthony; Trebes, James; Borchers, Robert

2013-01-01

At the request of the Domestic Nuclear Detection Office (DNDO), a Review Committee comprised of representatives from the American Physical Society (APS) Panel on Public Affairs (POPA) and the Institute of Electrical and Electronics Engineers (IEEE) Nuclear and Plasma Sciences Society (NPSS) performed a technical review of the DNDO Transformational and Applied Research Directorate (TARD) research and development program. TARD’s principal objective is to address gaps in the Global Nuclear Detection Architecture (GNDA) through improvements in the performance, cost, and operational burden of detectors and systems. The charge to the Review Committee was to investigate the existing TARD research andmore » development plan and portfolio, recommend changes to the existing plan, and recommend possible new R&D areas and opportunities. The Review Committee has several recommendations.« less

Space Applications in Support of Future Urban Development in Armenia

NASA Astrophysics Data System (ADS)

Alhaddad, Bahaaeddin; Reppucci, Antonio; Moreno, Laura

2016-08-01

The fast growing of some cities has produced important changes in the urban sectors not always following sustainability criteria. As results, most urban growth falls outside formal planning controls and many cities suffer poor urban services management, traffic, and congestion, loss of green areas, poor air quality, and noise. The main advantages of satellite-based EO products are to support the decision-making process, and the development and operation of smart services. Satellite-based urban morphology analysis can help to identify the transformation of the urban development and evolution. The pilot presented here is a demonstration in the framework of the collaboration between ESA and ADB, called EOTAP "Earth Observation for a Transforming Asia Pacific". Aim of the pilot is to exploit satellite Earth observation data for sustainable growth and help preparing a series of city development and investment plans.

Convex reformulation of biologically-based multi-criteria intensity-modulated radiation therapy optimization including fractionation effects

NASA Astrophysics Data System (ADS)

Hoffmann, Aswin L.; den Hertog, Dick; Siem, Alex Y. D.; Kaanders, Johannes H. A. M.; Huizenga, Henk

2008-11-01

Finding fluence maps for intensity-modulated radiation therapy (IMRT) can be formulated as a multi-criteria optimization problem for which Pareto optimal treatment plans exist. To account for the dose-per-fraction effect of fractionated IMRT, it is desirable to exploit radiobiological treatment plan evaluation criteria based on the linear-quadratic (LQ) cell survival model as a means to balance the radiation benefits and risks in terms of biologic response. Unfortunately, the LQ-model-based radiobiological criteria are nonconvex functions, which make the optimization problem hard to solve. We apply the framework proposed by Romeijn et al (2004 Phys. Med. Biol. 49 1991-2013) to find transformations of LQ-model-based radiobiological functions and establish conditions under which transformed functions result in equivalent convex criteria that do not change the set of Pareto optimal treatment plans. The functions analysed are: the LQ-Poisson-based model for tumour control probability (TCP) with and without inter-patient heterogeneity in radiation sensitivity, the LQ-Poisson-based relative seriality s-model for normal tissue complication probability (NTCP), the equivalent uniform dose (EUD) under the LQ-Poisson model and the fractionation-corrected Probit-based model for NTCP according to Lyman, Kutcher and Burman. These functions differ from those analysed before in that they cannot be decomposed into elementary EUD or generalized-EUD functions. In addition, we show that applying increasing and concave transformations to the convexified functions is beneficial for the piecewise approximation of the Pareto efficient frontier.

TU-F-BRF-02: MR-US Prostate Registration Using Patient-Specific Tissue Elasticity Property Prior for MR-Targeted, TRUS-Guided HDR Brachytherapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yang, X; Rossi, P; Ogunleye, T

2014-06-15

Purpose: High-dose-rate (HDR) brachytherapy has become a popular treatment modality for prostate cancer. Conventional transrectal ultrasound (TRUS)-guided prostate HDR brachytherapy could benefit significantly from MR-targeted, TRUS-guided procedure where the tumor locations, acquired from the multiparametric MRI, are incorporated into the treatment planning. In order to enable this integration, we have developed a MR-TRUS registration with a patient-specific biomechanical elasticity prior. Methods: The proposed method used a biomechanical elasticity prior to guide the prostate volumetric B-spline deformation in the MRI and TRUS registration. The patient-specific biomechanical elasticity prior was generated using ultrasound elastography, where two 3D TRUS prostate images were acquiredmore » under different probe-induced pressures during the HDR procedure, which takes 2-4 minutes. These two 3D TRUS images were used to calculate the local displacement (elasticity map) of two prostate volumes. The B-spline transformation was calculated by minimizing the Euclidean distance between the normalized attribute vectors of the prostate surface landmarks on the MR and TRUS. This technique was evaluated through two studies: a prostate-phantom study and a pilot study with 5 patients undergoing prostate HDR treatment. The accuracy of our approach was assessed through the locations of several landmarks in the post-registration and TRUS images; our registration results were compared with the surface-based method. Results: For the phantom study, the mean landmark displacement of the proposed method was 1.29±0.11 mm. For the 5 patients, the mean landmark displacement of the surface-based method was 3.25±0.51 mm; our method, 1.71±0.25 mm. Therefore, our proposed method of prostate registration outperformed the surfaced-based registration significantly. Conclusion: We have developed a novel MR-TRUS prostate registration approach based on patient-specific biomechanical elasticity prior. Successful integration of multi-parametric MR and TRUS prostate images provides a prostate-cancer map for treatment planning, enables accurate dose planning and delivery, and potentially enhances prostate HDR treatment outcome.« less

Solution of Fifth-order Korteweg and de Vries Equation by Homotopy perturbation Transform Method using He's Polynomial

NASA Astrophysics Data System (ADS)

Sharma, Dinkar; Singh, Prince; Chauhan, Shubha

2017-06-01

In this paper, a combined form of the Laplace transform method with the homotopy perturbation method is applied to solve nonlinear fifth order Korteweg de Vries (KdV) equations. The method is known as homotopy perturbation transform method (HPTM). The nonlinear terms can be easily handled by the use of He's polynomials. Two test examples are considered to illustrate the present scheme. Further the results are compared with Homotopy perturbation method (HPM).

Market-implied spread for earthquake CAT bonds: financial implications of engineering decisions.

PubMed

Damnjanovic, Ivan; Aslan, Zafer; Mander, John

2010-12-01

In the event of natural and man-made disasters, owners of large-scale infrastructure facilities (assets) need contingency plans to effectively restore the operations within the acceptable timescales. Traditionally, the insurance sector provides the coverage against potential losses. However, there are many problems associated with this traditional approach to risk transfer including counterparty risk and litigation. Recently, a number of innovative risk mitigation methods, termed alternative risk transfer (ART) methods, have been introduced to address these problems. One of the most important ART methods is catastrophe (CAT) bonds. The objective of this article is to develop an integrative model that links engineering design parameters with financial indicators including spread and bond rating. The developed framework is based on a four-step structural loss model and transformed survival model to determine expected excess returns. We illustrate the framework for a seismically designed bridge using two unique CAT bond contracts. The results show a nonlinear relationship between engineering design parameters and market-implied spread. © 2010 Society for Risk Analysis.

A study of radar cross section measurement techniques

NASA Technical Reports Server (NTRS)

Mcdonald, Malcolm W.

1986-01-01

Past, present, and proposed future technologies for the measurement of radar cross section were studied. The purpose was to determine which method(s) could most advantageously be implemented in the large microwave anechoic chamber facility which is operated at the antenna test range site. The progression toward performing radar cross section measurements of space vehicles with which the Orbital Maneuvering Vehicle will be called upon to rendezvous and dock is a natural outgrowth of previous work conducted in recent years of developing a high accuracy range and velocity sensing radar system. The radar system was designed to support the rendezvous and docking of the Orbital Maneuvering Vehicle with various other space vehicles. The measurement of radar cross sections of space vehicles will be necessary in order to plan properly for Orbital Maneuvering Vehicle rendezvous and docking assignments. The methods which were studied include: standard far-field measurements; reflector-type compact range measurements; lens-type compact range measurement; near field/far field transformations; and computer predictive modeling. The feasibility of each approach is examined.

General properties of the Foldy-Wouthuysen transformation and applicability of the corrected original Foldy-Wouthuysen method

NASA Astrophysics Data System (ADS)

Silenko, Alexander J.

2016-02-01

General properties of the Foldy-Wouthuysen transformation which is widely used in quantum mechanics and quantum chemistry are considered. Merits and demerits of the original Foldy-Wouthuysen transformation method are analyzed. While this method does not satisfy the Eriksen condition of the Foldy-Wouthuysen transformation, it can be corrected with the use of the Baker-Campbell-Hausdorff formula. We show a possibility of such a correction and propose an appropriate algorithm of calculations. An applicability of the corrected Foldy-Wouthuysen method is restricted by the condition of convergence of a series of relativistic corrections.

Face recognition using slow feature analysis and contourlet transform

NASA Astrophysics Data System (ADS)

Wang, Yuehao; Peng, Lingling; Zhe, Fuchuan

2018-04-01

In this paper we propose a novel face recognition approach based on slow feature analysis (SFA) in contourlet transform domain. This method firstly use contourlet transform to decompose the face image into low frequency and high frequency part, and then takes technological advantages of slow feature analysis for facial feature extraction. We named the new method combining the slow feature analysis and contourlet transform as CT-SFA. The experimental results on international standard face database demonstrate that the new face recognition method is effective and competitive.

Accounting for direction and speed of eye motion in planning visually guided manual tracking.

PubMed

Leclercq, Guillaume; Blohm, Gunnar; Lefèvre, Philippe

2013-10-01

Accurate motor planning in a dynamic environment is a critical skill for humans because we are often required to react quickly and adequately to the visual motion of objects. Moreover, we are often in motion ourselves, and this complicates motor planning. Indeed, the retinal and spatial motions of an object are different because of the retinal motion component induced by self-motion. Many studies have investigated motion perception during smooth pursuit and concluded that eye velocity is partially taken into account by the brain. Here we investigate whether the eye velocity during ongoing smooth pursuit is taken into account for the planning of visually guided manual tracking. We had 10 human participants manually track a target while in steady-state smooth pursuit toward another target such that the difference between the retinal and spatial target motion directions could be large, depending on both the direction and the speed of the eye. We used a measure of initial arm movement direction to quantify whether motor planning occurred in retinal coordinates (not accounting for eye motion) or was spatially correct (incorporating eye velocity). Results showed that the eye velocity was nearly fully taken into account by the neuronal areas involved in the visuomotor velocity transformation (between 75% and 102%). In particular, these neuronal pathways accounted for the nonlinear effects due to the relative velocity between the target and the eye. In conclusion, the brain network transforming visual motion into a motor plan for manual tracking adequately uses extraretinal signals about eye velocity.

A new wavelet transform to sparsely represent cortical current densities for EEG/MEG inverse problems.

PubMed

Liao, Ke; Zhu, Min; Ding, Lei

2013-08-01

The present study investigated the use of transform sparseness of cortical current density on human brain surface to improve electroencephalography/magnetoencephalography (EEG/MEG) inverse solutions. Transform sparseness was assessed by evaluating compressibility of cortical current densities in transform domains. To do that, a structure compression method from computer graphics was first adopted to compress cortical surface structure, either regular or irregular, into hierarchical multi-resolution meshes. Then, a new face-based wavelet method based on generated multi-resolution meshes was proposed to compress current density functions defined on cortical surfaces. Twelve cortical surface models were built by three EEG/MEG softwares and their structural compressibility was evaluated and compared by the proposed method. Monte Carlo simulations were implemented to evaluate the performance of the proposed wavelet method in compressing various cortical current density distributions as compared to other two available vertex-based wavelet methods. The present results indicate that the face-based wavelet method can achieve higher transform sparseness than vertex-based wavelet methods. Furthermore, basis functions from the face-based wavelet method have lower coherence against typical EEG and MEG measurement systems than vertex-based wavelet methods. Both high transform sparseness and low coherent measurements suggest that the proposed face-based wavelet method can improve the performance of L1-norm regularized EEG/MEG inverse solutions, which was further demonstrated in simulations and experimental setups using MEG data. Thus, this new transform on complicated cortical structure is promising to significantly advance EEG/MEG inverse source imaging technologies. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Research on Rigid Body Motion Tracing in Space based on NX MCD

NASA Astrophysics Data System (ADS)

Wang, Junjie; Dai, Chunxiang; Shi, Karen; Qin, Rongkang

2018-03-01

In the use of MCD (Mechatronics Concept Designer) which is a module belong to SIEMENS Ltd industrial design software UG (Unigraphics NX), user can define rigid body and kinematic joint to make objects move according to the existing plan in simulation. At this stage, user may have the desire to see the path of some points in the moving object intuitively. In response to this requirement, this paper will compute the pose through the transformation matrix which can be available from the solver engine, and then fit these sampling points through B-spline curve. Meanwhile, combined with the actual constraints of rigid bodies, the traditional equal interval sampling strategy was optimized. The result shown that this method could satisfy the demand and make up for the deficiency in traditional sampling method. User can still edit and model on this 3D curve. Expected result has been achieved.

Improvement of the System of Training of Specialists by University for Coal Mining Enterprises

NASA Astrophysics Data System (ADS)

Mikhalchenko, Vadim; Seredkina, Irina

2017-11-01

In the article the ingenious technique of the Quality Function Deployment with reference to the process of training of specialists with higher education by university is considered. The method is based on the step-by-step conversion of customer requirements into specific organizational, meaningful and functional transformations of the technological process of the university. A fully deployed quality function includes four stages of tracking customer requirements while creating a product: product planning and design, process design, production design. The Quality Function Deployment can be considered as one of the methods for optimizing the technological processes of training of specialists with higher education in the current economic conditions. Implemented at the initial stages of the life cycle of the technological process, it ensures not only the high quality of the "product" of graduate school, but also the fullest possible satisfaction of consumer's requests and expectations.

Organizational ergonomics of occupational health methods and processes in a Brazilian oil refinery.

PubMed

Bau, Lucy M S; Farias, Jean P; Buso, Sandro A; Passero, Carolina R Marcon

2012-01-01

Organizational ergonomics refers to the optimization of social technical systems, including their organizational structures, policies and processes. The relevant topics include communications, management of resources, work projects, temporal organization of work, team work, participative project, new work paradigms, cooperative work, organizational culture, network organizations and quality management (IEA, 2000). The purpose of this study was the reorganization of the methods and processes of the occupational health sector (SMS/SO - Portuguese acronym of the area) of a petrochemical company. The work involved thirty professionals: a coordinator, two occupational physicians, one cardiologist, one occupational dentist, two occupational nurses, eleven occupational health technicians, one social worker, one nutritionist, one phonoaudiologist, one ophthalmologist, one biochemist, two ergonomists, three administrative assistants, one administrator and one psychologist, during a six-month period. The methodology that was used sought to establish a cooperative alliance focused on change, transformation and acquisition of skills, reflecting directly on the attitudes and performance of the leaderships and their work teams. In addition to the feedback practice, the following supporting tools were used for the study's success: "Functional Polyvalence Matrix", "Management of Failures", 5W2H", "6M", "5 Why" and "process mapping". The intended results after the organization ergonomics restructuring process will allow the leader to help his or her team to make a diagnosis of the problems, identify options, develop strategies, establish targets and action plans, remove barriers, review contexts and implement the business management fundaments: planning, organization, management, coordination and control. The transformation possibilities allow us to consider some hypothesis: Before: Focus only on results. After: Engage collaborators to create sustainable results. Before: Operating profile. After: Tactical/strategic profile. Before: Find errors. After: Value effort and development. Before: Listen to what is being said. After: Understand what is being said. Before: Create fears of the consequences. After: Create room for risk. Before: Be the one who approves and decides. After: Be the cooperative support.

Computationally efficient method for Fourier transform of highly chirped pulses for laser and parametric amplifier modeling.

PubMed

Andrianov, Alexey; Szabo, Aron; Sergeev, Alexander; Kim, Arkady; Chvykov, Vladimir; Kalashnikov, Mikhail

2016-11-14

We developed an improved approach to calculate the Fourier transform of signals with arbitrary large quadratic phase which can be efficiently implemented in numerical simulations utilizing Fast Fourier transform. The proposed algorithm significantly reduces the computational cost of Fourier transform of a highly chirped and stretched pulse by splitting it into two separate transforms of almost transform limited pulses, thereby reducing the required grid size roughly by a factor of the pulse stretching. The application of our improved Fourier transform algorithm in the split-step method for numerical modeling of CPA and OPCPA shows excellent agreement with standard algorithms.

Efficient regeneration and improved sonication-assisted Agrobacterium transformation (SAAT) method for Catharanthus roseus.

PubMed

Alam, Pravej; Khan, Zainul Abdeen; Abdin, Malik Zainul; Khan, Jawaid A; Ahmad, Parvaiz; Elkholy, Shereen F; Sharaf-Eldin, Mahmoud A

2017-05-01

Catharanthus roseus is an important medicinal plant known for its pharmacological qualities such as antimicrobial, anticancerous, antifeedant, antisterility, antidiabetic activities. More than 130 bioactive compounds like vinblastine, vindoline and vincristine have been synthesized in this plant. Extensive studies have been carried out for optimization regeneration and transformation protocols. Most of the protocol described are laborious and time-consuming. Due to sophisticated protocol of regeneration and genetic transformation, the production of these bioactive molecules is less and not feasible to be commercialized worldwide. Here we have optimized the efficient protocol for regeneration and transformation to minimize the time scale and enhance the transformation frequency through Agrobacterium and sonication-assisted transformation (SAAT) method. In this study, hypocotyl explants responded best for maximal production of transformed shoots. The callus percentage were recorded 52% with 1.0 mg L -1 (BAP) and 0.5 mg L -1 (NAA) while 80% shoot percentage obtained with 4.0 mg L -1 (BAP) and 0.05 mg L -1 (NAA). The microscopic studies revealed that the expression of GFP was clearly localized in leaf tissue of the C. roseus after transformation of pRepGFP0029 construct. Consequently, transformation efficiency was revealed on the basis of GFP localization. The transformation efficiency of SAAT method was 6.0% comparable to 3.5% as conventional method. Further, PCR analysis confirmed the integration of the nptII gene in the transformed plantlets of C. roseus.

An optical Fourier transform coprocessor with direct phase determination.

PubMed

Macfaden, Alexander J; Gordon, George S D; Wilkinson, Timothy D

2017-10-20

The Fourier transform is a ubiquitous mathematical operation which arises naturally in optics. We propose and demonstrate a practical method to optically evaluate a complex-to-complex discrete Fourier transform. By implementing the Fourier transform optically we can overcome the limiting O(nlogn) complexity of fast Fourier transform algorithms. Efficiently extracting the phase from the well-known optical Fourier transform is challenging. By appropriately decomposing the input and exploiting symmetries of the Fourier transform we are able to determine the phase directly from straightforward intensity measurements, creating an optical Fourier transform with O(n) apparent complexity. Performing larger optical Fourier transforms requires higher resolution spatial light modulators, but the execution time remains unchanged. This method could unlock the potential of the optical Fourier transform to permit 2D complex-to-complex discrete Fourier transforms with a performance that is currently untenable, with applications across information processing and computational physics.

A New Instantaneous Frequency Measure Based on The Stockwell Transform

NASA Astrophysics Data System (ADS)

yedlin, M. J.; Ben-Horrin, Y.; Fraser, J. D.

2011-12-01

We propose the use of a new transform, the Stockwell transform[1], as a means of creating time-frequency maps and applying them to distinguish blasts from earthquakes. This new transform, the Stockwell transform can be considered as a variant of the continuous wavelet transform, that preserves the absolute phase.The Stockwell transform employs a complex Morlet mother wavelet. The novelty of this transform lies in its resolution properties. High frequencies in the candidate signal are well-resolved in time but poorly resolved in frequency, while the converse is true for low frequency signal components. The goal of this research is to obtain the instantaneous frequency as a function of time for both the earthquakes and the blasts. Two methods will be compared. In the first method, we will compute the analytic signal, the envelope and the instantaneous phase as a function of time[2]. The instantaneous phase derivative will yield the instantaneous angular frequency. The second method will be based on time-frequency analysis using the Stockwell transform. The Stockwell transform will be computed in non-redundant fashion using a dyadic representation[3]. For each time-point, the frequency centroid will be computed -- a representation for the most likely frequency at that time. A detailed comparison will be presented for both approaches to the computation of the instantaneous frequency. An advantage of the Stockwell approach is that no differentiation is applied. The Hilbert transform method can be less sensitive to edge effects. The goal of this research is to see if the new Stockwell-based method could be used as a discriminant between earthquakes and blasts. References [1] Stockwell, R.G., Mansinha, L. and Lowe, R.P. "Localization of the complex spectrum: the S transform", IEEE Trans. Signal Processing, vol.44, no.4, pp.998-1001, (1996). [2]Taner, M.T., Koehler, F. "Complex seismic trace analysis", Geophysics, vol. 44, Issue 6, pp. 1041-1063 (1979). [3] Brown, R.A., Lauzon, M.L. and Frayne, R. "General Description of Linear Time-Frequency Transforms and Formulation of a Fast, Invertible Transform That Samples the Continuous S-Transform Spectrum Nonredundantly", IEEE Transactions on Signal Processing, 1:281-90 (2010).

Improved remote gaze estimation using corneal reflection-adaptive geometric transforms

NASA Astrophysics Data System (ADS)

Ma, Chunfei; Baek, Seung-Jin; Choi, Kang-A.; Ko, Sung-Jea

2014-05-01

Recently, the remote gaze estimation (RGE) technique has been widely applied to consumer devices as a more natural interface. In general, the conventional RGE method estimates a user's point of gaze using a geometric transform, which represents the relationship between several infrared (IR) light sources and their corresponding corneal reflections (CRs) in the eye image. Among various methods, the homography normalization (HN) method achieves state-of-the-art performance. However, the geometric transform of the HN method requiring four CRs is infeasible for the case when fewer than four CRs are available. To solve this problem, this paper proposes a new RGE method based on three alternative geometric transforms, which are adaptive to the number of CRs. Unlike the HN method, the proposed method not only can operate with two or three CRs, but can also provide superior accuracy. To further enhance the performance, an effective error correction method is also proposed. By combining the introduced transforms with the error-correction method, the proposed method not only provides high accuracy and robustness for gaze estimation, but also allows for a more flexible system setup with a different number of IR light sources. Experimental results demonstrate the effectiveness of the proposed method.

Solution of time fractional Black-Scholes European option pricing equation arising in financial market

NASA Astrophysics Data System (ADS)

Ravi Kanth, A. S. V.; Aruna, K.

2016-12-01

In this paper, we present fractional differential transform method (FDTM) and modified fractional differential transform method (MFDTM) for the solution of time fractional Black-Scholes European option pricing equation. The method finds the solution without any discretization, transformation, or restrictive assumptions with the use of appropriate initial or boundary conditions. The efficiency and exactitude of the proposed methods are tested by means of three examples.

Fusing terrain and goals: agent control in urban environments

NASA Astrophysics Data System (ADS)

Kaptan, Varol; Gelenbe, Erol

2006-04-01

The changing face of contemporary military conflicts has forced a major shift of focus in tactical planning and evaluation from the classical Cold War battlefield to an asymmetric guerrilla-type warfare in densely populated urban areas. The new arena of conflict presents unique operational difficulties due to factors like complex mobility restrictions and the necessity to preserve civilian lives and infrastructure. In this paper we present a novel method for autonomous agent control in an urban environment. Our approach is based on fusing terrain information and agent goals for the purpose of transforming the problem of navigation in a complex environment with many obstacles into the easier problem of navigation in a virtual obstacle-free space. The main advantage of our approach is its ability to act as an adapter layer for a number of efficient agent control techniques which normally show poor performance when applied to an environment with many complex obstacles. Because of the very low computational and space complexity at runtime, our method is also particularly well suited for simulation or control of a huge number of agents (military as well as civilian) in a complex urban environment where traditional path-planning may be too expensive or where a just-in-time decision with hard real-time constraints is required.

Establishment of an efficient transformation system for Pleurotus ostreatus.

PubMed

Lei, Min; Wu, Xiangli; Zhang, Jinxia; Wang, Hexiang; Huang, Chenyang

2017-11-21

Pleurotus ostreatus is widely cultivated worldwide, but the lack of an efficient transformation system regarding its use restricts its genetic research. The present study developed an improved and efficient Agrobacterium tumefaciens-mediated transformation method in P. ostreatus. Four parameters were optimized to obtain the most efficient transformation method. The strain LBA4404 was the most suitable for the transformation of P. ostreatus. A bacteria-to-protoplast ratio of 100:1, an acetosyringone (AS) concentration of 0.1 mM, and 18 h of co-culture showed the best transformation efficiency. The hygromycin B phosphotransferase gene (HPH) was used as the selective marker, and EGFP was used as the reporter gene in this study. Southern blot analysis combined with EGFP fluorescence assay showed positive results, and mitotic stability assay showed that more than 75% transformants were stable after five generations. These results showed that our transformation method is effective and stable and may facilitate future genetic studies in P. ostreatus.

The whole number axis integer linear transformation reversible information hiding algorithm on wavelet domain

NASA Astrophysics Data System (ADS)

Jiang, Zhuo; Xie, Chengjun

2013-12-01

This paper improved the algorithm of reversible integer linear transform on finite interval [0,255], which can realize reversible integer linear transform in whole number axis shielding data LSB (least significant bit). Firstly, this method use integer wavelet transformation based on lifting scheme to transform the original image, and select the transformed high frequency areas as information hiding area, meanwhile transform the high frequency coefficients blocks in integer linear way and embed the secret information in LSB of each coefficient, then information hiding by embedding the opposite steps. To extract data bits and recover the host image, a similar reverse procedure can be conducted, and the original host image can be lossless recovered. The simulation experimental results show that this method has good secrecy and concealment, after conducted the CDF (m, n) and DD (m, n) series of wavelet transformed. This method can be applied to information security domain, such as medicine, law and military.

Person-centered care planning and service engagement: a study protocol for a randomized controlled trial.

PubMed

Stanhope, Victoria; Tondora, Janis; Davidson, Larry; Choy-Brown, Mimi; Marcus, Steven C

2015-04-22

Service disengagement is a pervasive challenge the mental health care system faces. Mental health services are of little value should persons with mental illnesses continue to opt out of receiving them. Consumers attribute disengagement from care to an absence of choice in their treatment. In response, the mental health system is adopting a person-centered model, based upon recovery principles, to engage consumers more actively in their care. Person-centered care planning is a promising practice involving collaboration to develop and implement an actionable plan to assist the person in achieving personal recovery goals. This study design combines a parallel-group randomized controlled trial of community mental health organizations with qualitative methods to assess the effectiveness of person-centered care planning. Participants at 14 sites in Delaware and Connecticut will be randomized to treatment as usual or the person-centered care planning intervention. Participants will be in leadership (n = 70) or supervisory or direct care (n = 210) roles. The person-centered care planning intervention involves intensive staff training and 12 months of ongoing technical assistance. Quantitative survey data will be collected at baseline, 6 months and 12 months measuring person-centered care planning competency and organizational factors. Consumer outcomes (engagement, medication adherence, functioning and consumer satisfaction) will be assessed by Medicaid and state-level data. Qualitative data focused on process factors will include staff and consumer interviews and focus groups. In this intent-to-treat analysis, we will use mixed-effects multivariate regression models to evaluate the differential impact of the person-centered care planning intervention on each consumer and implementation outcome as well as the extent to which clinician assessments of organizational factors are associated with the implementation outcome. Mixed methods will triangulate and strengthen the interpretation of outcomes. The aim of this study is to generate valuable guidance for state systems engaged in scale-up and transformation efforts. Targeted staff selection for training to support sustainability will serve to provide further insight into important intervention implementation strategies. Person-centered care planning has the potential to enhance the impact of all evidence-based and recovery-oriented practices and bring practice into line with the emerging national guidelines in health care reform. This trial was registered with ClinicalTrials.gov (Identifier: NCT02299492) on 21 November 2014 as New York University Protocol Record PCCP-13-9762, Person-Centered Care Planning and Service Engagement.

Building a transformative adaptation: Comparing municipal government’ and community’s initiatives on minimizing the risk of coastal inundation in Pekalongan

NASA Astrophysics Data System (ADS)

Artiningsih; Worosuprojo, S.; Rijanta, R.; Hardoyo, S. R.; Pratama, M. H. S.; Putri, N. C.

2017-06-01

In 2006, coastal inundation was firstly reported to start entering community’s agriculture land in Northern part of Pekalongan, Central Java, Indonesia. The exposure covered most of paddy fields and fishponds. The disturbance has become bigger, when the exposure of coastal inundation has started to cover some part of settlement areas in 2010. Increasing salinity has prevented farmers to grow paddy cultivation and has forced them to find a new way for living. Pekalongan Municipal Government prepared Pekalongan City’s Resilience Strategy (PCRS) in 2010 in cooperation with PAKLIM-GIZ, and it involved significant and meaningful local stakeholders’ participation process. One of the concerning strategies was to minimize the risk of coastal inundation. In terms of PCRS implementation, observed local community has different planning interpretation in comparison to the municipal government. This paper aims to evaluate the implementation of PCRS by comparing the municipal government’ and community’s initiatives - either in the stage of planning or/and implementation - from a transformative adaptation perspective. Data for this study was collected through interviews with several key informants, who were selected by purposive sampling method. These key informants consist of Pekalongan Municipal Government Agencies’ members and local community figures in Northern Pekalongan Sub-district. This research reveals a double development standard from the side of municipal government, when it comes to prioritize both the economy and the environment. However, the local community prefers to choose a new livelihood, which provides them not just economic security, but also social and ecological benefits.

Development of a Coordinate Transformation method for direct georeferencing in map projection frames

NASA Astrophysics Data System (ADS)

Zhao, Haitao; Zhang, Bing; Wu, Changshan; Zuo, Zhengli; Chen, Zhengchao

2013-03-01

This paper develops a novel Coordinate Transformation method (CT-method), with which the orientation angles (roll, pitch, heading) of the local tangent frame of the GPS/INS system are transformed into those (omega, phi, kappa) of the map projection frame for direct georeferencing (DG). Especially, the orientation angles in the map projection frame were derived from a sequence of coordinate transformations. The effectiveness of orientation angles transformation was verified through comparing with DG results obtained from conventional methods (Legat method and POSPac method) using empirical data. Moreover, the CT-method was also validated with simulated data. One advantage of the proposed method is that the orientation angles can be acquired simultaneously while calculating position elements of exterior orientation (EO) parameters and auxiliary points coordinates by coordinate transformation. These three methods were demonstrated and compared using empirical data. Empirical results show that the CT-method is both as sound and effective as Legat method. Compared with POSPac method, the CT-method is more suitable for calculating EO parameters for DG in map projection frames. DG accuracy of the CT-method and Legat method are at the same level. DG results of all these three methods have systematic errors in height due to inconsistent length projection distortion in the vertical and horizontal components, and these errors can be significantly reduced using the EO height correction technique in Legat's approach. Similar to the results obtained with empirical data, the effectiveness of the CT-method was also proved with simulated data. POSPac method: The method is presented by Applanix POSPac software technical note (Hutton and Savina, 1997). It is implemented in the POSEO module of POSPac software.

A Power Transformers Fault Diagnosis Model Based on Three DGA Ratios and PSO Optimization SVM

NASA Astrophysics Data System (ADS)

Ma, Hongzhe; Zhang, Wei; Wu, Rongrong; Yang, Chunyan

2018-03-01

In order to make up for the shortcomings of existing transformer fault diagnosis methods in dissolved gas-in-oil analysis (DGA) feature selection and parameter optimization, a transformer fault diagnosis model based on the three DGA ratios and particle swarm optimization (PSO) optimize support vector machine (SVM) is proposed. Using transforming support vector machine to the nonlinear and multi-classification SVM, establishing the particle swarm optimization to optimize the SVM multi classification model, and conducting transformer fault diagnosis combined with the cross validation principle. The fault diagnosis results show that the average accuracy of test method is better than the standard support vector machine and genetic algorithm support vector machine, and the proposed method can effectively improve the accuracy of transformer fault diagnosis is proved.

Reengineering the picture archiving and communication system (PACS) process for digital imaging networks PACS.

PubMed

Horton, M C; Lewis, T E; Kinsey, T V

1999-05-01

Prior to June 1997, military picture archiving and communications systems (PACS) were planned, procured, and installed with key decisions on the system, equipment, and even funding sources made through a research and development office called Medical Diagnostic Imaging Systems (MDIS). Beginning in June 1997, the Joint Imaging Technology Project Office (JITPO) initiated a collaborative and consultative process for planning and implementing PACS into military treatment facilities through a new Department of Defense (DoD) contract vehicle called digital imaging networks (DIN)-PACS. The JITPO reengineered this process incorporating multiple organizations and politics. The reengineered PACS process administered through the JITPO transformed the decision process and accountability from a single office to a consultative method that increased end-user knowledge, responsibility, and ownership in PACS. The JITPO continues to provide information and services that assist multiple groups and users in rendering PACS planning and implementation decisions. Local site project managers are involved from the outset and this end-user collaboration has made the sometimes difficult transition to PACS an easier and more acceptable process for all involved. Corporately, this process saved DoD sites millions by having PACS plans developed within the government and proposed to vendors second, and then having vendors respond specifically to those plans. The integrity and efficiency of the process have reduced the opportunity for implementing nonstandard systems while sharing resources and reducing wasted government dollars. This presentation will describe the chronology of changes, encountered obstacles, and lessons learned within the reengineering of the PACS process for DIN-PACS.

Tensor Fukunaga-Koontz transform for small target detection in infrared images

NASA Astrophysics Data System (ADS)

Liu, Ruiming; Wang, Jingzhuo; Yang, Huizhen; Gong, Chenglong; Zhou, Yuanshen; Liu, Lipeng; Zhang, Zhen; Shen, Shuli

2016-09-01

Infrared small targets detection plays a crucial role in warning and tracking systems. Some novel methods based on pattern recognition technology catch much attention from researchers. However, those classic methods must reshape images into vectors with the high dimensionality. Moreover, vectorizing breaks the natural structure and correlations in the image data. Image representation based on tensor treats images as matrices and can hold the natural structure and correlation information. So tensor algorithms have better classification performance than vector algorithms. Fukunaga-Koontz transform is one of classification algorithms and it is a vector version method with the disadvantage of all vector algorithms. In this paper, we first extended the Fukunaga-Koontz transform into its tensor version, tensor Fukunaga-Koontz transform. Then we designed a method based on tensor Fukunaga-Koontz transform for detecting targets and used it to detect small targets in infrared images. The experimental results, comparison through signal-to-clutter, signal-to-clutter gain and background suppression factor, have validated the advantage of the target detection based on the tensor Fukunaga-Koontz transform over that based on the Fukunaga-Koontz transform.

Developing a nurse-led clinic using transformational leadership.

PubMed

Gousy, Mamood; Green, Kim

2015-03-25

Nurses are at the forefront of implementing and managing change, given constantly changing healthcare services and the increase in demand for health care. Therefore, it is important to identify the best style of leadership to engage nurses in implementing service-led improvements. This article explores the effects of transformational leadership in bringing about service-led improvements in health care, using the example of setting up a nurse-led acupuncture clinic to optimise the care of patients with chronic pain. Transformational leadership was used throughout the project - from the initial local planning, training and development, through to liaising with the appropriate staff and deciding on an evaluation strategy. Transformational leadership proved to be an effective way to engage and empower nurses and other members of the chronic pain team to enable them to achieve the project aims.

Comparison between iteration schemes for three-dimensional coordinate-transformed saturated-unsaturated flow model

NASA Astrophysics Data System (ADS)

An, Hyunuk; Ichikawa, Yutaka; Tachikawa, Yasuto; Shiiba, Michiharu

2012-11-01

SummaryThree different iteration methods for a three-dimensional coordinate-transformed saturated-unsaturated flow model are compared in this study. The Picard and Newton iteration methods are the common approaches for solving Richards' equation. The Picard method is simple to implement and cost-efficient (on an individual iteration basis). However it converges slower than the Newton method. On the other hand, although the Newton method converges faster, it is more complex to implement and consumes more CPU resources per iteration than the Picard method. The comparison of the two methods in finite-element model (FEM) for saturated-unsaturated flow has been well evaluated in previous studies. However, two iteration methods might exhibit different behavior in the coordinate-transformed finite-difference model (FDM). In addition, the Newton-Krylov method could be a suitable alternative for the coordinate-transformed FDM because it requires the evaluation of a 19-point stencil matrix. The formation of a 19-point stencil is quite a complex and laborious procedure. Instead, the Newton-Krylov method calculates the matrix-vector product, which can be easily approximated by calculating the differences of the original nonlinear function. In this respect, the Newton-Krylov method might be the most appropriate iteration method for coordinate-transformed FDM. However, this method involves the additional cost of taking an approximation at each Krylov iteration in the Newton-Krylov method. In this paper, we evaluated the efficiency and robustness of three iteration methods—the Picard, Newton, and Newton-Krylov methods—for simulating saturated-unsaturated flow through porous media using a three-dimensional coordinate-transformed FDM.

Application of differential transformation method for solving dengue transmission mathematical model

NASA Astrophysics Data System (ADS)

Ndii, Meksianis Z.; Anggriani, Nursanti; Supriatna, Asep K.

2018-03-01

The differential transformation method (DTM) is a semi-analytical numerical technique which depends on Taylor series and has application in many areas including Biomathematics. The aim of this paper is to employ the differential transformation method (DTM) to solve system of non-linear differential equations for dengue transmission mathematical model. Analytical and numerical solutions are determined and the results are compared to that of Runge-Kutta method. We found a good agreement between DTM and Runge-Kutta method.

Achieving Unity of Effort: Leveraging Interagency Cooperation Between the Department of Defense (DOD) and the United States Agency for International Development (USAID)

DTIC Science & Technology

2009-06-12

Government Printing Office, 2005), 2. 12 Carlos Pascual, ―Unifying our Approach to Conflict Transformation ,‖ U.S. Department of State, http...1 Peter F. Schaefer and P. Clayton Schaefer, ―Planning for Reconstruction and Transformation of Japan after WWII,‖ Applying a ‘Whole-of- Government ...Iraq and continuing challenges. Given, these experiences, senior military and civilian leaders alike have called for a ―whole of government

Bringing the OhioHealth Nursing Strategic Plan to Life With the AONE Care Innovation and Transformation Program.

PubMed

Dials, Kelly; Gossett, Lisa; Osting, Lindsey; Rutherford, David; Stifter, Janet

2017-12-01

Contemporary CNOs are committed to developing the next generation of nurse leaders. At OhioHealth, the nursing strategic vision includes the belief that every nurse will be a leader in improving health across the care continuum. In 2016, the OhioHealth System partnered with AONE to participate in the Care Innovation and Transformation program resulting in bedside nurses living this strategic vision and creating positive changes in quality, safety, and satisfaction for patients and families.

A method to analyze molecular tagging velocimetry data using the Hough transform.

PubMed

Sanchez-Gonzalez, R; McManamen, B; Bowersox, R D W; North, S W

2015-10-01

The development of a method to analyze molecular tagging velocimetry data based on the Hough transform is presented. This method, based on line fitting, parameterizes the grid lines "written" into a flowfield. Initial proof-of-principle illustration of this method was performed to obtain two-component velocity measurements in the wake of a cylinder in a Mach 4.6 flow, using a data set derived from computational fluid dynamics simulations. The Hough transform is attractive for molecular tagging velocimetry applications since it is capable of discriminating spurious features that can have a biasing effect in the fitting process. Assessment of the precision and accuracy of the method were also performed to show the dependence on analysis window size and signal-to-noise levels. The accuracy of this Hough transform-based method to quantify intersection displacements was determined to be comparable to cross-correlation methods. The employed line parameterization avoids the assumption of linearity in the vicinity of each intersection, which is important in the limit of drastic grid deformations resulting from large velocity gradients common in high-speed flow applications. This Hough transform method has the potential to enable the direct and spatially accurate measurement of local vorticity, which is important in applications involving turbulent flowfields. Finally, two-component velocity determinations using the Hough transform from experimentally obtained images are presented, demonstrating the feasibility of the proposed analysis method.

Study protocol: cross-national comparative case study of recovery-focused mental health care planning and coordination (COCAPP).

PubMed

Simpson, Alan; Hannigan, Ben; Coffey, Michael; Jones, Aled; Barlow, Sally; Cohen, Rachel; Všetečková, Jitka; Faulkner, Alison; Haddad, Mark

2015-07-03

The collaborative care planning study (COCAPP) is a cross-national comparative study of care planning and coordination in community mental healthcare settings. The context and delivery of mental health care is diverging between the countries of England and Wales whilst retaining points of common interest, hence providing a rich geographical comparison for research. Across England the key vehicle for the provision of recovery-focused, personalised, collaborative mental health care is the care programme approach (CPA). The CPA is a form of case management introduced in England in 1991, then revised in 2008. In Wales the CPA was introduced in 2003 but has now been superseded by The Mental Health (Care Co-ordination and Care and Treatment Planning) (CTP) Regulations (Mental Health Measure), a new statutory framework. In both countries, the CPA/CTP requires providers to: comprehensively assess health/social care needs and risks; develop a written care plan (which may incorporate risk assessments, crisis and contingency plans, advanced directives, relapse prevention plans, etc.) in collaboration with the service user and carer(s); allocate a care coordinator; and regularly review care. The overarching aim of this study is to identify and describe the factors that ensure CPA/CTP care planning and coordination is personalised, recovery-focused and conducted collaboratively. COCAPP will employ a concurrent transformative mixed methods approach with embedded case studies. Phase 1 (Macro-level) will consider the national context through a meta-narrative mapping (MNM) review of national policies and the relevant research literature. Phase 2 (Meso-level and Micro-level) will include in-depth micro-level case studies of everyday 'frontline' practice and experience with detailed qualitative data from interviews and reviews of individual care plans. This will be nested within larger meso-level survey datasets, senior-level interviews and policy reviews in order to provide potential explanations and understanding. COCAPP will help identify the key components that support and hinder the provision of personalised, recovery-focused care planning and provide an informed rationale for a future planned intervention and evaluation.

Can Perceptions of Environmental and Climate Change in Island Communities Assist in Adaptation Planning Locally?

PubMed

Aswani, Shankar; Vaccaro, Ismael; Abernethy, Kirsten; Albert, Simon; de Pablo, Javier Fernández-López

2015-12-01

Local perceptions of environmental and climate change, as well as associated adaptations made by local populations, are fundamental for designing comprehensive and inclusive mitigation and adaptation plans both locally and nationally. In this paper, we analyze people's perceptions of environmental and climate-related transformations in communities across the Western Solomon Islands through ethnographic and geospatial methods. Specifically, we documented people's observed changes over the past decades across various environmental domains, and for each change, we asked respondents to identify the causes, timing, and people's adaptive responses. We also incorporated this information into a geographical information system database to produce broad-scale base maps of local perceptions of environmental change. Results suggest that people detected changes that tended to be acute (e.g., water clarity, logging intensity, and agricultural diseases). We inferred from these results that most local observations of and adaptations to change were related to parts of environment/ecosystem that are most directly or indirectly related to harvesting strategies. On the other hand, people were less aware of slower insidious/chronic changes identified by scientific studies. For the Solomon Islands and similar contexts in the insular tropics, a broader anticipatory adaptation planning strategy to climate change should include a mix of local scientific studies and local observations of ongoing ecological changes.

Planning Ahead: Object-Directed Sequential Actions Decoded from Human Frontoparietal and Occipitotemporal Networks

PubMed Central

Gallivan, Jason P.; Johnsrude, Ingrid S.; Randall Flanagan, J.

2016-01-01

Object-manipulation tasks (e.g., drinking from a cup) typically involve sequencing together a series of distinct motor acts (e.g., reaching toward, grasping, lifting, and transporting the cup) in order to accomplish some overarching goal (e.g., quenching thirst). Although several studies in humans have investigated the neural mechanisms supporting the planning of visually guided movements directed toward objects (such as reaching or pointing), only a handful have examined how manipulatory sequences of actions—those that occur after an object has been grasped—are planned and represented in the brain. Here, using event-related functional MRI and pattern decoding methods, we investigated the neural basis of real-object manipulation using a delayed-movement task in which participants first prepared and then executed different object-directed action sequences that varied either in their complexity or final spatial goals. Consistent with previous reports of preparatory brain activity in non-human primates, we found that activity patterns in several frontoparietal areas reliably predicted entire action sequences in advance of movement. Notably, we found that similar sequence-related information could also be decoded from pre-movement signals in object- and body-selective occipitotemporal cortex (OTC). These findings suggest that both frontoparietal and occipitotemporal circuits are engaged in transforming object-related information into complex, goal-directed movements. PMID:25576538

A Method to Compute the Force Signature of a Body Impacting on a Linear Elastic Structure Using Fourier Analysis

DTIC Science & Technology

1982-09-17

FK * 1PK (2) The convolution of two transforms in time domain is the inverse transform of the product in frequency domain. Thus Rp(s) - Fgc() Ipg(*) (3...its inverse transform by: R,(r)- R,(a.)e’’ do. (5)2w In order to nuke use f a very accurate numerical method to ompute Fourier "ke and coil...taorm. When the inverse transform it tken by using Eq. (15), the cosine transform, because it converges faster than the sine transform refu-ft the

Applying Triple-Matrix Masking for Privacy Preserving Data Collection and Sharing in HIV Studies.

PubMed

Pei, Qinglin; Chen, Shigang; Xiao, Yao; Wu, Samuel S

2016-01-01

Many HIV research projects are plagued by the high missing rate of selfreported information during data collection. Also, due to the sensitive nature of the HIV research data, privacy protection is always a concern for data sharing in HIV studies. This paper applies a data masking approach, called triple-matrix masking [1], to the context of HIV research for ensuring privacy protection during the process of data collection and data sharing. Using a set of generated HIV patient data, we show step by step how the data are randomly transformed (masked) before leaving the patients' individual data collection device (which ensures that nobody sees the actual data) and how the masked data are further transformed by a masking service provider and a data collector. We demonstrate that the masked data retain statistical utility of the original data, yielding the exactly same inference results in the planned logistic regression on the effect of age on the adherence to antiretroviral therapy and in the Cox proportional hazard model for the age effect on time to viral load suppression. Privacy-preserving data collection method may help resolve the privacy protection issue in HIV research. The individual sensitive data can be completely hidden while the same inference results can still be obtained from the masked data, with the use of common statistical analysis methods.

The future in Agricultural Engineering: news degrees in the Universidad Politécnica de Madrid (UPM)

NASA Astrophysics Data System (ADS)

Cartagena, M. Carmen; Tarquis, A. M.; Vázquez, J.; Serrano, A.; Arce, A.

2010-05-01

The Bologna process is to improve the quality of education, mobility, diversity and the competitiveness and involves three fundamental changes: transform of the structure of titles, changing in methods of teaching and implementation of the systems of quality assurance. Engineer Agronomist at the Universidad Politécnica de Madrid (UPM) has been offered as a degree of five years with a total of 400 credits and seven optional orientations: Crop Production, Plant and Breeding Protection, Environment, Agricultural Economics, Animal Production, Rural Engineering and Food Technology. Actually, the Bologna plan creates three new degrees: Engineering and Science Agronomic, Food Engineering and Agro-Environmental Engineering, with 240 ECTS each one of them and with specific professional characteristics. The changes that involve the introduction of these new degrees is perhaps the largest occurred never at the Spanish university system, not only by the drastic transformation in the structure of titles, but also by the new changes that lie ahead in teaching methods. Among others we will comment the following ones: -A year decreased duration of studies and therefore incorporation into the market. - Elimination of the seven current guidelines to create three specific qualifications of degree. -Decrease of optional subjects and increase in credits for the basic subjects. - Inclusion of business practices. - Increase in the number of credits of final project. - Changes in methodologies and a higher involvement of teachers and students in the education.

Biolistic transformation of cotton zygotic embryo meristem

USDA-ARS?s Scientific Manuscript database

Biolistic transformation of cotton meristems, isolated from mature seed is detailed in this book chapter. This method is simple and avoids the necessity to use genotype-dependent regenerable cell cultures. However, identification of germ line transformation using this method is laborious and time-c...

Genetic transformation of the yeast Dekkera/Brettanomyces bruxellensis with non-homologous DNA.

PubMed

Miklenić, Marina; Štafa, Anamarija; Bajić, Ana; Žunar, Bojan; Lisnić, Berislav; Svetec, Ivan-Krešimir

2013-05-01

Yeast Dekkera/Brettanomyces bruxellensis is probably the most common contaminant in wineries and ethanol production processes. The considerable economic losses caused by this yeast, but also its ability to produce and tolerate high ethanol concentrations, make it an attractive subject for research with potential for industrial applications. Unfortunately, efforts to understand the biology of D. bruxellensis and facilitate its broader use in industry are hampered by the lack of adequate procedures for delivery of exogenous DNA into this organism. Here we describe the development of transformation protocols (spheroplast transformation, LiAc/PEG method, and electroporation) and report the first genetic transformation of yeast D. bruxellensis. A linear heterologous DNA fragment carrying the kanMX4 sequence was used for transformation, which allowed transformants to be selected on plates containing geneticin. We found the spheroplast transformation method using 1M sorbitol as osmotic stabilizer to be inappropriate because sorbitol strikingly decreases the plating efficiency of both D. bruxellensis spheroplast and intact cells. However, we managed to modify the LiAc/ PEG transformation method and electroporation to accommodate D. bruxellensis transformation, achieving efficiencies of 0.6-16 and 10-20 transformants/microg DNA, respectively. The stability of the transformants ranged from 93.6% to 100%. All putative transformants were analyzed by Southern blot using the kanMX4 sequence as a hybridization probe, which confirmed that the transforming DNA fragment had integrated into the genome. The results of the molecular analysis were consistent with the expected illegitimate integration of a heterologous transforming fragment.

Being Relevant in Tough Times: TRIUMF's Five-Year Plan

ScienceCinema

Tim, Mayer [TRIUMF

2017-12-09

Perhaps better known to the international community than its own neighbors, TRIUMF is Canada's national laboratory for particle and nuclear physics.  Working with the Canadian scientific community, TRIUMF has formulated a new vision to transform the laboratory and deliver a whole new level of performance and impact.  The plan capitalizes on platform technologies (superconducting RF cavities for accelerator physics and radiotracers in nuclear medicine) and exploits Canada's role in ATLAS and the LHC.  I will describe the key elements of the plan and discuss the science-policy landscape in which TRIUMF must make its case.

Initial Integrated Strategic Sustainability Plan for Fort Leonard Wood

DTIC Science & Technology

2012-05-01

objective of this work was to develop the initial version of a 25-year ISSP incorporating FLW’s mission and vision with its energy, environmen- tal...plans outlining the tasks and resources needed to achieve the objectives; and development of metrics for assessing progress toward each objective... development and redevelopment at Fort Leonard Wood 4.1.1 Description In the next 25 years, transform into an Installation with an efficient net- work

Strategic Studies Quarterly. Volume 5, Number 2, Summer 2011

DTIC Science & Technology

2011-01-01

Afghanistan. We also made progress in our support of operational planning by the combatant commanders and in building processes for them to issue...transformation of the department’s networks; • work with the combatant commands to synchronize processes and planning to deliver the joint effects...own actions and forces. Note that these and many other factors determining the process of deter- rence have as much to do with an opponent’s unique

Hough transform method for track finding in center drift chamber

NASA Astrophysics Data System (ADS)

Azmi, K. A. Mohammad Kamal; Wan Abdullah, W. A. T.; Ibrahim, Zainol Abidin

2016-01-01

Hough transform is a global tracking method used which had been expected to be faster approach for tracking the circular pattern of electron moving in Center Drift Chamber (CDC), by transforming the point of hit into a circular curve. This paper present the implementation of hough transform method for the reconstruction of tracks in Center Drift Chamber (CDC) which have been generated by random number in C language programming. Result from implementation of this method shows higher peak of circle parameter value (xc,yc,rc) that indicate the similarity value of the parameter needed for circular track in CDC for charged particles in the region of CDC.

Controlling lightwave in Riemann space by merging geometrical optics with transformation optics.

PubMed

Liu, Yichao; Sun, Fei; He, Sailing

2018-01-11

In geometrical optical design, we only need to choose a suitable combination of lenses, prims, and mirrors to design an optical path. It is a simple and classic method for engineers. However, people cannot design fantastical optical devices such as invisibility cloaks, optical wormholes, etc. by geometrical optics. Transformation optics has paved the way for these complicated designs. However, controlling the propagation of light by transformation optics is not a direct design process like geometrical optics. In this study, a novel mixed method for optical design is proposed which has both the simplicity of classic geometrical optics and the flexibility of transformation optics. This mixed method overcomes the limitations of classic optical design; at the same time, it gives intuitive guidance for optical design by transformation optics. Three novel optical devices with fantastic functions have been designed using this mixed method, including asymmetrical transmissions, bidirectional focusing, and bidirectional cloaking. These optical devices cannot be implemented by classic optics alone and are also too complicated to be designed by pure transformation optics. Numerical simulations based on both the ray tracing method and full-wave simulation method are carried out to verify the performance of these three optical devices.

A decade of the Clinical Trials Transformation Initiative: What have we accomplished? What have we learned?

PubMed

Tenaerts, P; Madre, L; Landray, M

2018-02-01

The Clinical Trials Transformation Initiative reflects on 10 years of working to improve the quality and efficiency of clinical trials. This article highlights many of the Clinical Trials Transformation Initiative's accomplishments and offers examples of the impact that the Clinical Trials Transformation Initiative has had on the clinical trials enterprise. After conducting more than 25 projects and issuing recommendations for specific strategies to improve the design and execution of clinical trials, some common themes and lessons learned have emerged. Lessons include the importance of engaging many stakeholders, advanced planning to address critical issues, discontinuation of non-value added practices, and new opportunities presented by technology. Through its work, the Clinical Trials Transformation Initiative has also derived some operational best practices for conducting collaborative, multi-stakeholder projects covering project selection, project team dynamics and execution, and multi-stakeholder meetings and team discussions. Through these initiatives, the Clinical Trials Transformation Initiative has helped move the needle toward needed change in the clinical trials enterprise that has directly impacted stakeholders and patients alike.

Improvement of tissue culture, genetic transformation, and applications of biotechnology to Brassica.

PubMed

Ravanfar, Seyed Ali; Orbovic, Vladimir; Moradpour, Mahdi; Abdul Aziz, Maheran; Karan, Ratna; Wallace, Simon; Parajuli, Saroj

2017-04-01

Development of in vitro plant regeneration method from Brassica explants via organogenesis and somatic embryogenesis is influenced by many factors such as culture environment, culture medium composition, explant sources, and genotypes which are reviewed in this study. An efficient in vitro regeneration system to allow genetic transformation of Brassica is a crucial tool for improving its economical value. Methods to optimize transformation protocols for the efficient introduction of desirable traits, and a comparative analysis of these methods are also reviewed. Hence, binary vectors, selectable marker genes, minimum inhibitory concentration of selection agents, reporter marker genes, preculture media, Agrobacterium concentration and regeneration ability of putative transformants for improvement of Agrobacterium-mediated transformation of Brassica are discussed.

Further distinctive investigations of the Sumudu transform

NASA Astrophysics Data System (ADS)

Belgacem, Fethi Bin Muhammad; Silambarasan, Rathinavel

2017-01-01

The Sumudu transform of time function f (t) is computed by making the transform variable u of Sumudu as factor of function f (t) and then integrated against exp(-t). Being a factor in the original function f (t), becomes f (ut) preserves units and dimension. This preservation property distinguishes Sumudu from other integral transforms. With obtained definition, the related complete set of properties were derived for the Sumudu transform. Framgment of Symbolic C++ program was given for Sumudu computation as series. Also procedure in Maple was given for Sumudu computation in closed form. The Method proposed herein not depends neither on any of homotopy methods such as HPM, HAM nor any of decomposition methods such as ADM.

Quantum Optical Realization of Arbitrary Linear Transformations Allowing for Loss and Gain

NASA Astrophysics Data System (ADS)

Tischler, N.; Rockstuhl, C.; Słowik, K.

2018-04-01

Unitary transformations are routinely modeled and implemented in the field of quantum optics. In contrast, nonunitary transformations, which can involve loss and gain, require a different approach. In this work, we present a universal method to deal with nonunitary networks. An input to the method is an arbitrary linear transformation matrix of optical modes that does not need to adhere to bosonic commutation relations. The method constructs a transformation that includes the network of interest and accounts for full quantum optical effects related to loss and gain. Furthermore, through a decomposition in terms of simple building blocks, it provides a step-by-step implementation recipe, in a manner similar to the decomposition by Reck et al. [Experimental Realization of Any Discrete Unitary Operator, Phys. Rev. Lett. 73, 58 (1994), 10.1103/PhysRevLett.73.58] but applicable to nonunitary transformations. Applications of the method include the implementation of positive-operator-valued measures and the design of probabilistic optical quantum information protocols.

Appreciative inquiry with nurses who work with children of incarcerated parents.

PubMed

Falk, Kathleen J

2014-10-01

An appreciative inquiry study was conducted with 12 nurse-mentors who worked with children of incarcerated parents. The aim was to generate best practice knowledge for working with these children. The nurse-mentoring program, based on theorists Peplau and Erickson and colleagues, was implemented to promote optimum health outcomes among children at high risk for incarceration. Through this study method, nurse mentors discovered what was effective as they created a collective vision for future practice. An action plan was implemented, evaluated, and conclusions were drawn. Data from this study imply that nurse-mentoring can be used with other vulnerable populations. Nurses should use appreciative inquiry to transform healthcare, particularly in situations with seemingly intransigent solutions. © The Author(s) 2014.

Maslow and Mental Health Recovery: A Comparative Study of Homeless Programs for Adults with Serious Mental Illness

PubMed Central

Derejko, Katie-Sue; Couture, Julie; Padgett, Deborah K.

2014-01-01

This mixed-methods study uses Maslow’s hierarchy as a theoretical lens to investigate the experiences of 63 newly enrolled clients of housing first and traditional programs for adults with serious mental illness who have experienced homelessness. Quantitative findings suggests that identifying self-actualization goals is associated with not having one’s basic needs met rather than from the fulfillment of basic needs. Qualitative findings suggest a more complex relationship between basic needs, goal setting, and the meaning of self-actualization. Transforming mental health care into a recovery-oriented system will require further consideration of person-centered care planning as well as the impact of limited resources especially for those living in poverty. PMID:24518968

Maslow and mental health recovery: a comparative study of homeless programs for adults with serious mental illness.

PubMed

Henwood, Benjamin F; Derejko, Katie-Sue; Couture, Julie; Padgett, Deborah K

2015-03-01

This mixed-methods study uses Maslow's hierarchy as a theoretical lens to investigate the experiences of 63 newly enrolled clients of housing first and traditional programs for adults with serious mental illness who have experienced homelessness. Quantitative findings suggests that identifying self-actualization goals is associated with not having one's basic needs met rather than from the fulfillment of basic needs. Qualitative findings suggest a more complex relationship between basic needs, goal setting, and the meaning of self-actualization. Transforming mental health care into a recovery-oriented system will require further consideration of person-centered care planning as well as the impact of limited resources especially for those living in poverty.

Use of ultrasonic array method for positioning multiple partial discharge sources in transformer oil.

PubMed

Xie, Qing; Tao, Junhan; Wang, Yongqiang; Geng, Jianghai; Cheng, Shuyi; Lü, Fangcheng

2014-08-01

Fast and accurate positioning of partial discharge (PD) sources in transformer oil is very important for the safe, stable operation of power systems because it allows timely elimination of insulation faults. There is usually more than one PD source once an insulation fault occurs in the transformer oil. This study, which has both theoretical and practical significance, proposes a method of identifying multiple PD sources in the transformer oil. The method combines the two-sided correlation transformation algorithm in the broadband signal focusing and the modified Gerschgorin disk estimator. The method of classification of multiple signals is used to determine the directions of arrival of signals from multiple PD sources. The ultrasonic array positioning method is based on the multi-platform direction finding and the global optimization searching. Both the 4 × 4 square planar ultrasonic sensor array and the ultrasonic array detection platform are built to test the method of identifying and positioning multiple PD sources. The obtained results verify the validity and the engineering practicability of this method.

Study of Earthquake Disaster Prediction System of Langfang city Based on GIS

NASA Astrophysics Data System (ADS)

Huang, Meng; Zhang, Dian; Li, Pan; Zhang, YunHui; Zhang, RuoFei

2017-07-01

In this paper, according to the status of China’s need to improve the ability of earthquake disaster prevention, this paper puts forward the implementation plan of earthquake disaster prediction system of Langfang city based on GIS. Based on the GIS spatial database, coordinate transformation technology, GIS spatial analysis technology and PHP development technology, the seismic damage factor algorithm is used to predict the damage of the city under different intensity earthquake disaster conditions. The earthquake disaster prediction system of Langfang city is based on the B / S system architecture. Degree and spatial distribution and two-dimensional visualization display, comprehensive query analysis and efficient auxiliary decision-making function to determine the weak earthquake in the city and rapid warning. The system has realized the transformation of the city’s earthquake disaster reduction work from static planning to dynamic management, and improved the city’s earthquake and disaster prevention capability.

A method for encapsulating high voltage power transformers

NASA Astrophysics Data System (ADS)

Sanchez, Robert O.

Voltage breakdowns become a major concern in reducing the size of high-voltage power converter transformers. Even the smallest of voids can provide a path for corona discharge which can cause a dielectric breakdown leading to a transformer failure. A method of encapsulating small high voltage transformers has been developed. The method virtually eliminates voids in the impregnation material, provides an exceptional dielectric between windings and provides a mechanically rugged package. The encapsulation material is a carboxyl terminated butadiene nitril (CTBN) modified mica filled epoxy. The method requires heat/vacuum to impregnate the coil and heat/pressure to cure the encapsulant. The transformer package utilizes a diallyl phthalate (DAP) contact assembly in which a coated core/coil assembly is mounted and soldered. This assembly is then loaded into an RTV mold and the encapsulation process begins.

A novel method for improving the accuracy of coordinate transformation in multiple measurement systems

NASA Astrophysics Data System (ADS)

Liu, W. L.; Li, Y. W.

2017-09-01

Large-scale dimensional metrology usually requires a combination of multiple measurement systems, such as laser tracking, total station, laser scanning, coordinate measuring arm and video photogrammetry, etc. Often, the results from different measurement systems must be combined to provide useful results. The coordinate transformation is used to unify coordinate frames in combination; however, coordinate transformation uncertainties directly affect the accuracy of the final measurement results. In this paper, a novel method is proposed for improving the accuracy of coordinate transformation, combining the advantages of the best-fit least-square and radial basis function (RBF) neural networks. First of all, the configuration of coordinate transformation is introduced and a transformation matrix containing seven variables is obtained. Second, the 3D uncertainty of the transformation model and the residual error variable vector are established based on the best-fit least-square. Finally, in order to optimize the uncertainty of the developed seven-variable transformation model, we used the RBF neural network to identify the uncertainty of the dynamic, and unstructured, owing to its great ability to approximate any nonlinear function to the designed accuracy. Intensive experimental studies were conducted to check the validity of the theoretical results. The results show that the mean error of coordinate transformation decreased from 0.078 mm to 0.054 mm after using this method in contrast with the GUM method.

Missing texture reconstruction method based on error reduction algorithm using Fourier transform magnitude estimation scheme.

PubMed

Ogawa, Takahiro; Haseyama, Miki

2013-03-01

A missing texture reconstruction method based on an error reduction (ER) algorithm, including a novel estimation scheme of Fourier transform magnitudes is presented in this brief. In our method, Fourier transform magnitude is estimated for a target patch including missing areas, and the missing intensities are estimated by retrieving its phase based on the ER algorithm. Specifically, by monitoring errors converged in the ER algorithm, known patches whose Fourier transform magnitudes are similar to that of the target patch are selected from the target image. In the second approach, the Fourier transform magnitude of the target patch is estimated from those of the selected known patches and their corresponding errors. Consequently, by using the ER algorithm, we can estimate both the Fourier transform magnitudes and phases to reconstruct the missing areas.

Viscoelastic damped response of cross-ply laminated shallow spherical shells subjected to various impulsive loads

NASA Astrophysics Data System (ADS)

Şahan, Mehmet Fatih

2017-11-01

In this paper, the viscoelastic damped response of cross-ply laminated shallow spherical shells is investigated numerically in a transformed Laplace space. In the proposed approach, the governing differential equations of cross-ply laminated shallow spherical shell are derived using the dynamic version of the principle of virtual displacements. Following this, the Laplace transform is employed in the transient analysis of viscoelastic laminated shell problem. Also, damping can be incorporated with ease in the transformed domain. The transformed time-independent equations in spatial coordinate are solved numerically by Gauss elimination. Numerical inverse transformation of the results into the real domain are operated by the modified Durbin transform method. Verification of the presented method is carried out by comparing the results with those obtained by the Newmark method and ANSYS finite element software. Furthermore, the developed solution approach is applied to problems with several impulsive loads. The novelty of the present study lies in the fact that a combination of the Navier method and Laplace transform is employed in the analysis of cross-ply laminated shallow spherical viscoelastic shells. The numerical sample results have proved that the presented method constitutes a highly accurate and efficient solution, which can be easily applied to the laminated viscoelastic shell problems.

Analysis and application of Fourier transform spectroscopy in atmospheric remote sensing

NASA Technical Reports Server (NTRS)

Park, J. H.

1984-01-01

An analysis method for Fourier transform spectroscopy is summarized with applications to various types of distortion in atmospheric absorption spectra. This analysis method includes the fast Fourier transform method for simulating the interferometric spectrum and the nonlinear least-squares method for retrieving the information from a measured spectrum. It is shown that spectral distortions can be simulated quite well and that the correct information can be retrieved from a distorted spectrum by this analysis technique.

Phase retrieval of singular scalar light fields using a two-dimensional directional wavelet transform and a spatial carrier.

PubMed

Federico, Alejandro; Kaufmann, Guillermo H

2008-10-01

We evaluate a method based on the two-dimensional directional wavelet transform and the introduction of a spatial carrier to retrieve optical phase distributions in singular scalar light fields. The performance of the proposed phase-retrieval method is compared with an approach based on Fourier transform. The advantages and limitations of the proposed method are discussed.

Shape-preserving transformations of organic matter and compositions thereof

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kaehr, Bryan J.; Meyer, Kristin; Townson, Jason L.

The present invention relates to methods of transforming organic matter into organic-inorganic composites, inorganic replicas, or conductive replicas. Organic matter, such as biological cells and tissue and organs, can be converted into such composites and replicas using the methods described herein. In particular, such methods transform organic matter (into inorganic, organic-inorganic, or conductive constructs), while simultaneously preserving microscopic and/or macroscopic structural detail.

Facilitating Personal Transformations in Small Groups: Part I.

ERIC Educational Resources Information Center

Boyd, Robert D.

1989-01-01

Describes personal transformation in small groups method that employs Matrix Model as its operational structure in Part I of two-part article. Describes method's reliance on metaphors and nature and manner in which they are employed. Defines personal transformation within framework of analytical psychology. (Author/CM)

Collaborative Autoethnography as a Pathway for Transformative Learning

ERIC Educational Resources Information Center

Blalock, A. Emiko; Akehi, Meg

2018-01-01

Through the exercise of collaborative autoethnography, we propose intentional and purposeful dialogue can act as a pathway for transformative learning. We seek to first deepen our understandings of transformative learning, particularly for underserved students in higher education and second to advance autoethnographic methods, a method that…

Development of 600 kV triple resonance pulse transformer.

PubMed

Li, Mingjia; Zhang, Faqiang; Liang, Chuan; Xu, Zhou

2015-06-01

In this paper, a triple-resonance pulse transformer based on an air-core transformer is introduced. The voltage across the high-voltage winding of the air-core transformer is significantly less than the output voltage; instead, the full output voltage appears across the tuning inductor. The maximum ratio of peak load voltage to peak transformer voltage is 2.77 in theory. By analyzing pulse transformer's lossless circuit, the analytical expression for the output voltage and the characteristic equation of the triple-resonance circuit are presented. Design method for the triple-resonance pulse transformer (iterated simulation method) is presented, and a triple-resonance pulse transformer is developed based on the existing air-core transformer. The experimental results indicate that the maximum ratio of peak voltage across the load to peak voltage across the high-voltage winding of the air-core transformer is approximately 2.0 and the peak output voltage of the triple-resonance pulse transformer is approximately 600 kV.

Time-resolved versus time-integrated portal dosimetry: the role of an object’s position with respect to the isocenter in volumetric modulated arc therapy

NASA Astrophysics Data System (ADS)

Schyns, Lotte E. J. R.; Persoon, Lucas C. G. G.; Podesta, Mark; van Elmpt, Wouter J. C.; Verhaegen, Frank

2016-05-01

The aim of this work is to compare time-resolved (TR) and time-integrated (TI) portal dosimetry, focussing on the role of an object’s position with respect to the isocenter in volumetric modulated arc therapy (VMAT). Portal dose images (PDIs) are simulated and measured for different cases: a sphere (1), a bovine bone (2) and a patient geometry (3). For the simulated case (1) and the experimental case (2), several transformations are applied at different off-axis positions. In the patient case (3), three simple plans with different isocenters are created and pleural effusion is simulated in the patient. The PDIs before and after the sphere transformations, as well as the PDIs with and without simulated pleural effusion, are compared using a TI and TR gamma analysis. In addition, the performance of the TI and TR gamma analyses for the detection of real geometric changes in patients treated with clinical plans is investigated and a correlation analysis is performed between gamma fail rates and differences in dose volume histogram (DVH) metrics. The TI gamma analysis can show large differences in gamma fail rates for the same transformation at different off-axis positions (or for different plan isocenters). The TR gamma analysis, however, shows consistent gamma fail rates. For the detection of real geometric changes in patients treated with clinical plans, the TR gamma analysis has a higher sensitivity than the TI gamma analysis. However, the specificity for the TR gamma analysis is lower than for the TI gamma analysis. Both the TI and TR gamma fail rates show no correlation with changes in DVH metrics. This work shows that TR portal dosimetry is fundamentally superior to TI portal dosimetry, because it removes the strong dependence of the gamma fail rate on the off-axis position/plan isocenter. However, for 2D TR portal dosimetry, it is still difficult to interpret gamma fail rates in terms of changes in DVH metrics for patients treated with VMAT.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, M; Suh, T; Cho, W

Purpose: A potential validation tool for compensating patient positioning error was developed using 2D/3D and 3D/3D image registration. Methods: For 2D/3D registration, digitally reconstructed radiography (DRR) and three-dimensional computed tomography (3D-CT) images were applied. The ray-casting algorithm is the most straightforward method for generating DRR. We adopted the traditional ray-casting method, which finds the intersections of a ray with all objects, voxels of the 3D-CT volume in the scene. The similarity between the extracted DRR and orthogonal image was measured by using a normalized mutual information method. Two orthogonal images were acquired from a Cyber-Knife system from the anterior-posterior (AP)more » and right lateral (RL) views. The 3D-CT and two orthogonal images of an anthropomorphic phantom and head and neck cancer patient were used in this study. For 3D/3D registration, planning CT and in-room CT image were applied. After registration, the translation and rotation factors were calculated to position a couch to be movable in six dimensions. Results: Registration accuracies and average errors of 2.12 mm ± 0.50 mm for transformations and 1.23° ± 0.40° for rotations were acquired by 2D/3D registration using an anthropomorphic Alderson-Rando phantom. In addition, registration accuracies and average errors of 0.90 mm ± 0.30 mm for transformations and 1.00° ± 0.2° for rotations were acquired using CT image sets. Conclusion: We demonstrated that this validation tool could compensate for patient positioning error. In addition, this research could be the fundamental step for compensating patient positioning error at the first Korea heavy-ion medical accelerator treatment center.« less

Investigating the Impact of NGSS-Aligned Professional Development on PreK-3 Teachers' Science Content Knowledge and Pedagogy

NASA Astrophysics Data System (ADS)

Tuttle, Nicole; Kaderavek, Joan N.; Molitor, Scott; Czerniak, Charlene M.; Johnson-Whitt, Eugenia; Bloomquist, Debra; Namatovu, Winnifred; Wilson, Grant

2016-11-01

This pilot study investigates the impact of a 2-week professional development Summer Institute on PK-3 teachers' knowledge and practices. This Summer Institute is a component of [program], a large-scale early-childhood science project that aims to transform PK-3 science teaching. The mixed-methods study examined concept maps, lesson plans, and classroom observations to measure possible changes in PK-3 teachers' science content knowledge and classroom practice from 11 teachers who attended the 2014 Summer Institute. Analysis of the concept maps demonstrated statistically significant growth in teachers' science content knowledge. Analysis of teachers' lesson plans demonstrated that the teachers could design high quality science inquiry lessons aligned to the Next Generation Science Standards following the professional development. Finally, examination of teachers' pre- and post-Summer Institute videotaped inquiry lessons showed evidence that teachers were incorporating new inquiry practices into their teaching, especially regarding classroom discourse. Our results suggest that an immersive inquiry experience is effective at beginning a shift towards reform-aligned science and engineering instruction but that early elementary educators require additional support for full mastery.

Highly Efficient Agrobacterium-Mediated Transformation of Wheat Via In Planta Inoculation

NASA Astrophysics Data System (ADS)

Risacher, Thierry; Craze, Melanie; Bowden, Sarah; Paul, Wyatt; Barsby, Tina

This chapter details a reproducible method for the transformation of spring wheat using Agrobacterium tumefaciens via the direct inoculation of bacteria into immature seeds in planta as described in patent WO 00/63398(1. Transformation efficiencies from 1 to 30% have been obtained and average efficiencies of at least 5% are routinely achieved. Regenerated plants are phenotypically normal with 30-50% of transformation events carrying introduced genes at single insertion sites, a higher rate than is typically reported for transgenic plants produced using biolistic transformation methods.

Wheat (Triticum aestivum L.) transformation using mature embryos.

PubMed

Medvecká, Eva; Harwood, Wendy A

2015-01-01

In most protocols for the Agrobacterium-mediated transformation of wheat, the preferred target tissues are immature embryos. However, transformation methods relying on immature embryos require the growth of plants under controlled conditions to provide a continuous supply of good-quality target tissue. The use of mature embryos as a target tissue has the advantage of only requiring good-quality seed as the starting material. Here we describe a transformation method based on the Agrobacterium-mediated transformation of callus cultures derived from mature wheat embryos of the genotype Bobwhite S56.

Multi-Scale Scattering Transform in Music Similarity Measuring

NASA Astrophysics Data System (ADS)

Wang, Ruobai

Scattering transform is a Mel-frequency spectrum based, time-deformation stable method, which can be used in evaluating music similarity. Compared with Dynamic time warping, it has better performance in detecting similar audio signals under local time-frequency deformation. Multi-scale scattering means to combine scattering transforms of different window lengths. This paper argues that, multi-scale scattering transform is a good alternative of dynamic time warping in music similarity measuring. We tested the performance of multi-scale scattering transform against other popular methods, with data designed to represent different conditions.

Gamma Knife surgery for arteriovenous malformations in the brain: integration of time-resolved contrast-enhanced magnetic resonance angiography into dosimetry planning. Technical note.

PubMed

Taschner, Christian A; Le Thuc, Vianney; Reyns, Nicolas; Gieseke, Juergen; Gauvrit, Jean-Yves; Pruvo, Jean-Pierre; Leclerc, Xavier

2007-10-01

The aim of this study was to develop an algorithm for the integration of time-resolved contrast-enhanced magnetic resonance (MR) angiography into dosimetry planning for Gamma Knife surgery (GKS) of arteriovenous malformations (AVMs) in the brain. Twelve patients harboring brain AVMs referred for GKS underwent intraarterial digital subtraction (DS) angiography and time-resolved MR angiography while wearing an externally applied cranial stereotactic frame. Time-resolved MR angiography was performed on a 1.5-tesla MR unit (Achieva, Philips Medical Systems) using contrast-enhanced 3D fast field echo sequencing with stochastic central k-space ordering. Postprocessing with interactive data language (Research Systems, Inc.) produced hybrid data sets containing dynamic angiographic information and the MR markers necessary for stereotactic transformation. Image files were sent to the Leksell GammaPlan system (Elekta) for dosimetry planning. Stereotactic transformation of the hybrid data sets containing the time-resolved MR angiography information with automatic detection of the MR markers was possible in all 12 cases. The stereotactic coordinates of vascular structures predefined from time-resolved MR angiography matched with DS angiography data in all cases. In 10 patients dosimetry planning could be performed based on time-resolved MR angiography data. In two patients, time-resolved MR angiography data alone were considered insufficient. The target volumes showed a notable shift of centers between modalities. Integration of time-resolved MR angiography data into the Leksell GammaPlan system for patients with brain AVMs is feasible. The proposed algorithm seems concise and sufficiently robust for clinical application. The quality of the time-resolved MR angiography sequencing needs further improvement.

Hospital on a page: standardizing data presentation to drive quality improvement.

PubMed

Heenan, Michael; DiEmanuele, Michelle; Hayward-Murray, Kathryn; Dadgar, Ladan

2012-01-01

Over the past five years, the Credit Valley Hospital (CVH) invested time and financial and human resources into performance measurement systems. In doing so, CVH launched a number of data tools including electronic scorecards and dashboards. However, the processes and accountability structures associated with the tools struggled to gain credibility with clinical and administrative leadership as the performance measurement system was primarily driven by the technology rather than a sound information strategy. Although a corporate-level scorecard was regularly updated, program-related scorecards and other measurement tools were only populated when programs reported to the board, at the time of accreditation or as a result of regulatory requirements. In addition, information contained in data reports was often presented in a manner that did not engage clinical and corporate decision-makers in the key issues of quality, access and sustainability. Following the release of its new strategic plan in 2009, CVH renewed its performance measurement framework and the methods by which it presented data so that the organization's strategic plan could be implemented and measured from the boardroom to the bedside. Long, complex spreadsheets were transformed into strategically designed, easy-to-understand, easy-to-access reports released in a standardized method in terms of format, media, content and timing. The following article describes the method CVH adopted to communicate the organization's performance and the role it played in enhancing the culture of quality and patient safety within the hospital.

Reference interval computation: which method (not) to choose?

PubMed

Pavlov, Igor Y; Wilson, Andrew R; Delgado, Julio C

2012-07-11

When different methods are applied to reference interval (RI) calculation the results can sometimes be substantially different, especially for small reference groups. If there are no reliable RI data available, there is no way to confirm which method generates results closest to the true RI. We randomly drawn samples obtained from a public database for 33 markers. For each sample, RIs were calculated by bootstrapping, parametric, and Box-Cox transformed parametric methods. Results were compared to the values of the population RI. For approximately half of the 33 markers, results of all 3 methods were within 3% of the true reference value. For other markers, parametric results were either unavailable or deviated considerably from the true values. The transformed parametric method was more accurate than bootstrapping for sample size of 60, very close to bootstrapping for sample size 120, but in some cases unavailable. We recommend against using parametric calculations to determine RIs. The transformed parametric method utilizing Box-Cox transformation would be preferable way of RI calculation, if it satisfies normality test. If not, the bootstrapping is always available, and is almost as accurate and precise as the transformed parametric method. Copyright © 2012 Elsevier B.V. All rights reserved.

Glass Bead-based Genetic Transformation:An Efficient Method for Transformation of Thraustochytrid Microorganisms.

PubMed

Adachi, Takumi; Sahara, Takehiko; Okuyama, Hidetoshi; Morita, Naoki

2017-07-01

Here, we describe a new method for genetic transformation of thraustochytrids, well-known producers of polyunsaturated fatty acids (PUFAs) like docosahexaenoic acid, by combining mild glass (zirconia) bead treatment and electroporation. Because the cell wall is a barrier against transfer of exogenous DNA into cells, gentle vortexing of cells with glass beads was performed prior to electroporation for partial cell wall disruption. G418-resistant transformants of thraustochytrid cells (Aurantiochytrium limacinum strain SR21 and thraustochytrid strain 12B) were successfully obtained with good reproducibility. The method reported here is simpler than methods using enzymes to generate spheroplasts and may provide advantages for PUFA production by using genetically modified thraustochytrids.

Hough transform method for track finding in center drift chamber

DOE Office of Scientific and Technical Information (OSTI.GOV)

Azmi, K. A. Mohammad Kamal, E-mail: khasmidatul@siswa.um.edu.my; Wan Abdullah, W. A. T., E-mail: wat@um.edu.my; Ibrahim, Zainol Abidin

Hough transform is a global tracking method used which had been expected to be faster approach for tracking the circular pattern of electron moving in Center Drift Chamber (CDC), by transforming the point of hit into a circular curve. This paper present the implementation of hough transform method for the reconstruction of tracks in Center Drift Chamber (CDC) which have been generated by random number in C language programming. Result from implementation of this method shows higher peak of circle parameter value (xc,yc,rc) that indicate the similarity value of the parameter needed for circular track in CDC for charged particlesmore » in the region of CDC.« less

Floral-Dip Transformation of Flax (Linum usitatissimum) to Generate Transgenic Progenies with a High Transformation Rate

PubMed Central

Bastaki, Nasmah K.; Cullis, Christopher A.

2014-01-01

Agrobacterium-mediated plant transformation via floral-dip is a widely used technique in the field of plant transformation and has been reported to be successful for many plant species. However, flax (Linum usitatissimum) transformation by floral-dip has not been reported. The goal of this protocol is to establish that Agrobacterium and the floral-dip method can be used to generate transgenic flax. We show that this technique is simple, inexpensive, efficient, and more importantly, gives a higher transformation rate than the current available methods of flax transformation. In summary, inflorescences of flax were dipped in a solution of Agrobacterium carrying a binary vector plasmid (T-DNA fragment plus the Linum Insertion Sequence, LIS-1) for 1 - 2 min. The plants were laid flat on their side for 24 hr. Then, plants were maintained under normal growth conditions until the next treatment. The process of dipping was repeated 2 - 3 times, with approximately 10 - 14 day intervals between dipping. The T1 seeds were collected and germinated on soil. After approximately two weeks, treated progenies were tested by direct PCR; 2 - 3 leaves were used per plant plus the appropriate T-DNA primers. Positive transformants were selected and grown to maturity. The transformation rate was unexpectedly high, with 50 - 60% of the seeds from treated plants being positive transformants. This is a higher transformation rate than those reported for Arabidopsis thaliana and other plant species, using floral-dip transformation. It is also the highest, which has been reported so far, for flax transformation using other methods for transformation. PMID:25549243

Floral-dip transformation of flax (Linum usitatissimum) to generate transgenic progenies with a high transformation rate.

PubMed

Bastaki, Nasmah K; Cullis, Christopher A

2014-12-19

Agrobacterium-mediated plant transformation via floral-dip is a widely used technique in the field of plant transformation and has been reported to be successful for many plant species. However, flax (Linum usitatissimum) transformation by floral-dip has not been reported. The goal of this protocol is to establish that Agrobacterium and the floral-dip method can be used to generate transgenic flax. We show that this technique is simple, inexpensive, efficient, and more importantly, gives a higher transformation rate than the current available methods of flax transformation. In summary, inflorescences of flax were dipped in a solution of Agrobacterium carrying a binary vector plasmid (T-DNA fragment plus the Linum Insertion Sequence, LIS-1) for 1 - 2 min. The plants were laid flat on their side for 24 hr. Then, plants were maintained under normal growth conditions until the next treatment. The process of dipping was repeated 2 - 3 times, with approximately 10 - 14 day intervals between dipping. The T1 seeds were collected and germinated on soil. After approximately two weeks, treated progenies were tested by direct PCR; 2 - 3 leaves were used per plant plus the appropriate T-DNA primers. Positive transformants were selected and grown to maturity. The transformation rate was unexpectedly high, with 50 - 60% of the seeds from treated plants being positive transformants. This is a higher transformation rate than those reported for Arabidopsis thaliana and other plant species, using floral-dip transformation. It is also the highest, which has been reported so far, for flax transformation using other methods for transformation.

A new method of converter transformer protection without commutation failure

NASA Astrophysics Data System (ADS)

Zhang, Jiayu; Kong, Bo; Liu, Mingchang; Zhang, Jun; Guo, Jianhong; Jing, Xu

2018-01-01

With the development of AC / DC hybrid transmission technology, converter transformer as nodes of AC and DC conversion of HVDC transmission technology, its reliable safe and stable operation plays an important role in the DC transmission. As a common problem of DC transmission, commutation failure poses a serious threat to the safe and stable operation of power grid. According to the commutation relation between the AC bus voltage of converter station and the output DC voltage of converter, the generalized transformation ratio is defined, and a new method of converter transformer protection based on generalized transformation ratio is put forward. The method uses generalized ratio to realize the on-line monitoring of the fault or abnormal commutation components, and the use of valve side of converter transformer bushing CT current characteristics of converter transformer fault accurately, and is not influenced by the presence of commutation failure. Through the fault analysis and EMTDC/PSCAD simulation, the protection can be operated correctly under the condition of various faults of the converter.

Experimental analysis and simulation calculation of the inductances of loosely coupled transformer

NASA Astrophysics Data System (ADS)

Kerui, Chen; Yang, Han; Yan, Zhang; Nannan, Gao; Ying, Pei; Hongbo, Li; Pei, Li; Liangfeng, Guo

2017-11-01

The experimental design of iron-core wireless power transmission system is designed, and an experimental model of loosely coupled transformer is built. Measuring the air gap on both sides of the transformer 15mm inductor under the parameters. The feasibility and feasibility of using the finite element method to calculate the coil inductance parameters of the loosely coupled transformer are analyzed. The system was modeled by ANSYS, and the magnetic field was calculated by finite element method, and the inductance parameters were calculated. The finite element method is used to calculate the inductive parameters of the loosely coupled transformer, and the basis for the accurate compensation of the capacitance of the wireless power transmission system is established.

Cloud-based Communications Planning Collaboration and Interoperability

DTIC Science & Technology

2012-06-01

battle concept is derived from the observation that all actions in the battle space have the ability to affect other areas or functions in the battle... space . This is equally true for tactical networks, which grow and transform dynamically as an operation evolves. Changes in one aspect of the network...availability of any updated network plans not only to the local SYSCON and TECHCON, but to all other units operating in the battle space (keeping in mind

The Application of Time-Frequency Methods to HUMS

NASA Technical Reports Server (NTRS)

Pryor, Anna H.; Mosher, Marianne; Lewicki, David G.; Norvig, Peter (Technical Monitor)

2001-01-01

This paper reports the study of four time-frequency transforms applied to vibration signals and presents a new metric for comparing them for fault detection. The four methods to be described and compared are the Short Time Frequency Transform (STFT), the Choi-Williams Distribution (WV-CW), the Continuous Wavelet Transform (CWT) and the Discrete Wavelet Transform (DWT). Vibration data of bevel gear tooth fatigue cracks, under a variety of operating load levels, are analyzed using these methods. The new metric for automatic fault detection is developed and can be produced from any systematic numerical representation of the vibration signals. This new metric reveals indications of gear damage with all of the methods on this data set. Analysis with the CWT detects mechanical problems with the test rig not found with the other transforms. The WV-CW and CWT use considerably more resources than the STFT and the DWT. More testing of the new metric is needed to determine its value for automatic fault detection and to develop methods of setting the threshold for the metric.

Developing nurses' transformational leadership skills.

PubMed

Fischer, Shelly Ann

2017-08-16

Healthcare is a complex area with significant potential for service improvement despite the effects of increasing economic and social pressures on the quality and safety of patient care. As the largest group of healthcare professionals in direct contact with patients, nurses are well positioned to contribute to improvements in healthcare services and to the development of new policies. To influence healthcare improvements and policies effectively, nurses require leadership skills. Historically, it was thought that only nurses in management roles required leadership skills; however, the ability to influence change is a requirement at all levels of clinical practice. Transformational leadership competencies provide nurses with the skills to contribute to improvements in the quality and safety of patient care, while enhancing their career satisfaction. This article examines how nurses can apply transformational leadership to their practice. It also informs nurses how to conduct an initial self-assessment of their leadership skills and to formulate a transformational leadership development plan.

Spatio-temporal interpolation of precipitation during monsoon periods in Pakistan

NASA Astrophysics Data System (ADS)

Hussain, Ijaz; Spöck, Gunter; Pilz, Jürgen; Yu, Hwa-Lung

2010-08-01

Spatio-temporal estimation of precipitation over a region is essential to the modeling of hydrologic processes for water resources management. The changes of magnitude and space-time heterogeneity of rainfall observations make space-time estimation of precipitation a challenging task. In this paper we propose a Box-Cox transformed hierarchical Bayesian multivariate spatio-temporal interpolation method for the skewed response variable. The proposed method is applied to estimate space-time monthly precipitation in the monsoon periods during 1974-2000, and 27-year monthly average precipitation data are obtained from 51 stations in Pakistan. The results of transformed hierarchical Bayesian multivariate spatio-temporal interpolation are compared to those of non-transformed hierarchical Bayesian interpolation by using cross-validation. The software developed by [11] is used for Bayesian non-stationary multivariate space-time interpolation. It is observed that the transformed hierarchical Bayesian method provides more accuracy than the non-transformed hierarchical Bayesian method.

High-Resolution Wind Measurements for Offshore Wind Energy Development

NASA Technical Reports Server (NTRS)

Nghiem, Son V.; Neumann, Gregory

2011-01-01

A mathematical transform, called the Rosette Transform, together with a new method, called the Dense Sampling Method, have been developed. The Rosette Transform is invented to apply to both the mean part and the fluctuating part of a targeted radar signature using the Dense Sampling Method to construct the data in a high-resolution grid at 1-km posting for wind measurements over water surfaces such as oceans or lakes.

Analogue Transformations in Physics and their Application to Acoustics

PubMed Central

García-Meca, C.; Carloni, S.; Barceló, C.; Jannes, G.; Sánchez-Dehesa, J.; Martínez, A.

2013-01-01

Transformation optics has shaped up a revolutionary electromagnetic design paradigm, enabling scientists to build astonishing devices such as invisibility cloaks. Unfortunately, the application of transformation techniques to other branches of physics is often constrained by the structure of the field equations. We develop here a complete transformation method using the idea of analogue spacetimes. The method is general and could be considered as a new paradigm for controlling waves in different branches of physics, from acoustics in quantum fluids to graphene electronics. As an application, we derive an “analogue transformation acoustics” formalism that naturally allows the use of transformations mixing space and time or involving moving fluids, both of which were impossible with the standard approach. To demonstrate the power of our method, we give explicit designs of a dynamic compressor, a spacetime cloak for acoustic waves and a carpet cloak for a moving aircraft. PMID:23774575

Prospective treatment plan-specific action limits for real-time intrafractional monitoring in surface image guided radiosurgery.

PubMed

Yock, Adam D; Pawlicki, Todd; Kim, Gwe-Ya

2016-07-01

In surface image guided radiosurgery, action limits are created to determine at what point intrafractional motion exhibited by the patient is large enough to warrant intervention. Action limit values remain constant across patients despite the fact that patient motion affects the target coverage of brain metastases differently depending on the planning technique and other treatment plan-specific factors. The purpose of this work was twofold. The first purpose was to characterize the sensitivity of single-met per iso and multimet per iso treatment plans to uncorrected patient motion. The second purpose was to describe a method to prospectively determine treatment plan-specific action limits considering this sensitivity. In their surface image guided radiosurgery technique, patient positioning is achieved with a thermoplastic mask that does not cover the patient's face. The patient's exposed face is imaged by a stereoscopic photogrammetry system. It is then compared to a reference surface and monitored throughout treatment. Seventy-two brain metastases (representing 29 patients) were used for this study. Twenty-five mets were treated individually ("single-met per iso plans"), and 47 were treated in a plan simultaneously with at least one other met ("multimet per iso plans"). For each met, the proportion of the gross tumor volume that remained within the 100% prescription isodose line was estimated under the influence of combinations of translations and rotations (0.0-3.0 mm and 0.0°-3.0°, respectively). The target volume and the prescription dose-volume were considered concentric spheres that each encompassed a volume determined from the treatment plan. Plan-specific contour plots and DVHs were created to illustrate the sensitivity of a specific lesion to uncorrected patient motion. Both single-met per iso and multimet per iso plans exhibited compromised target coverage under translations and rotations, though multimet per iso plans were considerably more sensitive to these transformations (2.3% and 39.8%, respectively). Plan-specific contour plots and DVHs were used to illustrate how size, distance from isocenter, and planning technique affect a particular met's sensitivity to motion. Stereotactic radiosurgery treatment plans that treat multiple brain metastases using a common isocenter are particularly susceptible to compromised target coverage as a result of uncorrected patient motion. The use of such a planning technique along with other treatment plan-specific factors should influence patient motion management. A graphical representation of the effect of translations and rotations on any particular plan can be generated to inform clinicians of the appropriate action limit when monitoring intrafractional motion.

A simple transformation independent method for outlier definition.

PubMed

Johansen, Martin Berg; Christensen, Peter Astrup

2018-04-10

Definition and elimination of outliers is a key element for medical laboratories establishing or verifying reference intervals (RIs). Especially as inclusion of just a few outlying observations may seriously affect the determination of the reference limits. Many methods have been developed for definition of outliers. Several of these methods are developed for the normal distribution and often data require transformation before outlier elimination. We have developed a non-parametric transformation independent outlier definition. The new method relies on drawing reproducible histograms. This is done by using defined bin sizes above and below the median. The method is compared to the method recommended by CLSI/IFCC, which uses Box-Cox transformation (BCT) and Tukey's fences for outlier definition. The comparison is done on eight simulated distributions and an indirect clinical datasets. The comparison on simulated distributions shows that without outliers added the recommended method in general defines fewer outliers. However, when outliers are added on one side the proposed method often produces better results. With outliers on both sides the methods are equally good. Furthermore, it is found that the presence of outliers affects the BCT, and subsequently affects the determined limits of current recommended methods. This is especially seen in skewed distributions. The proposed outlier definition reproduced current RI limits on clinical data containing outliers. We find our simple transformation independent outlier detection method as good as or better than the currently recommended methods.

Female Reproductive Tissues Are the Primary Target of Agrobacterium-Mediated Transformation by the Arabidopsis Floral-Dip Method1

PubMed Central

Desfeux, Christine; Clough, Steven J.; Bent, Andrew F.

2000-01-01

The floral-dip method for Agrobacterium-mediated transformation of Arabidopsis allows efficient plant transformation without need for tissue culture. To facilitate use with other plant species, we investigated the mechanisms that underlie this method. In manual outcrossing experiments, application of Agrobacterium tumefaciens to pollen donor plants did not produce any transformed progeny, whereas application of Agrobacterium to pollen recipient plants yielded transformants at a rate of 0.48%. Agrobacterium strains with T-DNA carrying gusA (encoding β-glucuronidase [GUS]) under the control of 35S, LAT52, or ACT11 promoters revealed delivery of GUS activity to developing ovules, whereas no GUS staining of pollen or pollen tubes was observed. Transformants derived from the same seed pod contained independent T-DNA integration events. In Arabidopsis flowers, the gynoecium develops as an open, vase-like structure that fuses to form closed locules roughly 3 d prior to anthesis. In correlation with this fact, we found that the timing of Agrobacterium infection was critical. Transformants were obtained and GUS staining of ovules and embryo sacs was observed only if the Agrobacterium were applied 5 d or more prior to anthesis. A 6-fold higher rate of transformation was obtained with a CRABS-CLAW mutant that maintains an open gynoecium. Our results suggest that ovules are the site of productive transformation in the floral-dip method, and further suggest that Agrobacterium must be delivered to the interior of the developing gynoecium prior to locule closure if efficient transformation is to be achieved. PMID:10889238

Female reproductive tissues are the primary target of Agrobacterium-mediated transformation by the Arabidopsis floral-dip method.

PubMed

Desfeux, C; Clough, S J; Bent, A F

2000-07-01

The floral-dip method for Agrobacterium-mediated transformation of Arabidopsis allows efficient plant transformation without need for tissue culture. To facilitate use with other plant species, we investigated the mechanisms that underlie this method. In manual outcrossing experiments, application of Agrobacterium tumefaciens to pollen donor plants did not produce any transformed progeny, whereas application of Agrobacterium to pollen recipient plants yielded transformants at a rate of 0.48%. Agrobacterium strains with T-DNA carrying gusA (encoding beta-glucuronidase [GUS]) under the control of 35S, LAT52, or ACT11 promoters revealed delivery of GUS activity to developing ovules, whereas no GUS staining of pollen or pollen tubes was observed. Transformants derived from the same seed pod contained independent T-DNA integration events. In Arabidopsis flowers, the gynoecium develops as an open, vase-like structure that fuses to form closed locules roughly 3 d prior to anthesis. In correlation with this fact, we found that the timing of Agrobacterium infection was critical. Transformants were obtained and GUS staining of ovules and embryo sacs was observed only if the Agrobacterium were applied 5 d or more prior to anthesis. A 6-fold higher rate of transformation was obtained with a CRABS-CLAW mutant that maintains an open gynoecium. Our results suggest that ovules are the site of productive transformation in the floral-dip method, and further suggest that Agrobacterium must be delivered to the interior of the developing gynoecium prior to locule closure if efficient transformation is to be achieved.