Numerical analysis of multicomponent responses of surface-hole transient electromagnetic method
NASA Astrophysics Data System (ADS)
Meng, Qing-Xin; Hu, Xiang-Yun; Pan, He-Ping; Zhou, Feng
2017-03-01
We calculate the multicomponent responses of surface-hole transient electromagnetic method. The methods and models are unsuitable as geoelectric models of conductive surrounding rocks because they are based on regular local targets. We also propose a calculation and analysis scheme based on numerical simulations of the subsurface transient electromagnetic fields. In the modeling of the electromagnetic fields, the forward modeling simulations are performed by using the finite-difference time-domain method and the discrete image method, which combines the Gaver-Stehfest inverse Laplace transform with the Prony method to solve the initial electromagnetic fields. The precision in the iterative computations is ensured by using the transmission boundary conditions. For the response analysis, we customize geoelectric models consisting of near-borehole targets and conductive wall rocks and implement forward modeling simulations. The observed electric fields are converted into induced electromotive force responses using multicomponent observation devices. By comparing the transient electric fields and multicomponent responses under different conditions, we suggest that the multicomponent-induced electromotive force responses are related to the horizontal and vertical gradient variations of the transient electric field at different times. The characteristics of the response are determined by the varying the subsurface transient electromagnetic fields, i.e., diffusion, attenuation and distortion, under different conditions as well as the electromagnetic fields at the observation positions. The calculation and analysis scheme of the response consider the surrounding rocks and the anomalous field of the local targets. It therefore can account for the geological data better than conventional transient field response analysis of local targets.
NASA Astrophysics Data System (ADS)
Wang, Xi; Yang, Bintang; Yu, Hu; Gao, Yulong
2017-04-01
The impulse excitation of mechanism causes transient vibration. In order to achieve adaptive transient vibration control, a method which can exactly model the response need to be proposed. This paper presents an analytical model to obtain the response of the primary system attached with dynamic vibration absorber (DVA) under impulse excitation. The impulse excitation which can be divided into single-impulse excitation and multi-impulse excitation is simplified as sinusoidal wave to establish the analytical model. To decouple the differential governing equations, a transform matrix is applied to convert the response from the physical coordinate to model coordinate. Therefore, the analytical response in the physical coordinate can be obtained by inverse transformation. The numerical Runge-Kutta method and experimental tests have demonstrated the effectiveness of the analytical model proposed. The wavelet of the response indicates that the transient vibration consists of components with multiple frequencies, and it shows that the modeling results coincide with the experiments. The optimizing simulations based on genetic algorithm and experimental tests demonstrate that the transient vibration of the primary system can be decreased by changing the stiffness of the DVA. The results presented in this paper are the foundations for us to develop the adaptive transient vibration absorber in the future.
Unsteady hovering wake parameters identified from dynamic model tests, part 1
NASA Technical Reports Server (NTRS)
Hohenemser, K. H.; Crews, S. T.
1977-01-01
The development of a 4-bladed model rotor is reported that can be excited with a simple eccentric mechanism in progressing and regressing modes with either harmonic or transient inputs. Parameter identification methods were applied to the problem of extracting parameters for linear perturbation models, including rotor dynamic inflow effects, from the measured blade flapping responses to transient pitch stirring excitations. These perturbation models were then used to predict blade flapping response to other pitch stirring transient inputs, and rotor wake and blade flapping responses to harmonic inputs. The viability and utility of using parameter identification methods for extracting the perturbation models from transients are demonstrated through these combined analytical and experimental studies.
On transient rheology and glacial isostasy
NASA Technical Reports Server (NTRS)
Yuen, David A.; Sabadini, Roberto C. A.; Gasperini, Paolo; Boschi, Enzo
1986-01-01
The effect of transient creep on the inference of long-term mantle viscosity is investigated using theoretical predictions from self-gravitating, layered earth models with Maxwell, Burgers' body, and standard linear solid rheologies. The interaction between transient and steady-state rheologies is studied. The responses of the standard linear solid and Burgers' body models to transient creep in the entire mantle, and of the Burgers' body and Maxwell models to creep in the lower mantle are described. The models' responses are examined in terms of the surface displacement, free air gravity anomaly, wander of the rotation pole, and the secular variation of the degree 2 zonal coefficient of the earth's gravitational potential field. The data reveal that transient creep cannot operate throughout the entire mantle.
Inhomogeneous Forcing and Transient Climate Sensitivity
NASA Technical Reports Server (NTRS)
Shindell, Drew T.
2014-01-01
Understanding climate sensitivity is critical to projecting climate change in response to a given forcing scenario. Recent analyses have suggested that transient climate sensitivity is at the low end of the present model range taking into account the reduced warming rates during the past 10-15 years during which forcing has increased markedly. In contrast, comparisons of modelled feedback processes with observations indicate that the most realistic models have higher sensitivities. Here I analyse results from recent climate modelling intercomparison projects to demonstrate that transient climate sensitivity to historical aerosols and ozone is substantially greater than the transient climate sensitivity to CO2. This enhanced sensitivity is primarily caused by more of the forcing being located at Northern Hemisphere middle to high latitudes where it triggers more rapid land responses and stronger feedbacks. I find that accounting for this enhancement largely reconciles the two sets of results, and I conclude that the lowest end of the range of transient climate response to CO2 in present models and assessments (less than 1.3 C) is very unlikely.
Encoding model of temporal processing in human visual cortex.
Stigliani, Anthony; Jeska, Brianna; Grill-Spector, Kalanit
2017-12-19
How is temporal information processed in human visual cortex? Visual input is relayed to V1 through segregated transient and sustained channels in the retina and lateral geniculate nucleus (LGN). However, there is intense debate as to how sustained and transient temporal channels contribute to visual processing beyond V1. The prevailing view associates transient processing predominately with motion-sensitive regions and sustained processing with ventral stream regions, while the opposing view suggests that both temporal channels contribute to neural processing beyond V1. Using fMRI, we measured cortical responses to time-varying stimuli and then implemented a two temporal channel-encoding model to evaluate the contributions of each channel. Different from the general linear model of fMRI that predicts responses directly from the stimulus, the encoding approach first models neural responses to the stimulus from which fMRI responses are derived. This encoding approach not only predicts cortical responses to time-varying stimuli from milliseconds to seconds but also, reveals differential contributions of temporal channels across visual cortex. Consistent with the prevailing view, motion-sensitive regions and adjacent lateral occipitotemporal regions are dominated by transient responses. However, ventral occipitotemporal regions are driven by both sustained and transient channels, with transient responses exceeding the sustained. These findings propose a rethinking of temporal processing in the ventral stream and suggest that transient processing may contribute to rapid extraction of the content of the visual input. Importantly, our encoding approach has vast implications, because it can be applied with fMRI to decipher neural computations in millisecond resolution in any part of the brain. Copyright © 2017 the Author(s). Published by PNAS.
Understanding Epileptiform After-Discharges as Rhythmic Oscillatory Transients.
Baier, Gerold; Taylor, Peter N; Wang, Yujiang
2017-01-01
Electro-cortical activity in patients with epilepsy may show abnormal rhythmic transients in response to stimulation. Even when using the same stimulation parameters in the same patient, wide variability in the duration of transient response has been reported. These transients have long been considered important for the mapping of the excitability levels in the epileptic brain but their dynamic mechanism is still not well understood. To investigate the occurrence of abnormal transients dynamically, we use a thalamo-cortical neural population model of epileptic spike-wave activity and study the interaction between slow and fast subsystems. In a reduced version of the thalamo-cortical model, slow wave oscillations arise from a fold of cycles (FoC) bifurcation. This marks the onset of a region of bistability between a high amplitude oscillatory rhythm and the background state. In vicinity of the bistability in parameter space, the model has excitable dynamics, showing prolonged rhythmic transients in response to suprathreshold pulse stimulation. We analyse the state space geometry of the bistable and excitable states, and find that the rhythmic transient arises when the impending FoC bifurcation deforms the state space and creates an area of locally reduced attraction to the fixed point. This area essentially allows trajectories to dwell there before escaping to the stable steady state, thus creating rhythmic transients. In the full thalamo-cortical model, we find a similar FoC bifurcation structure. Based on the analysis, we propose an explanation of why stimulation induced epileptiform activity may vary between trials, and predict how the variability could be related to ongoing oscillatory background activity. We compare our dynamic mechanism with other mechanisms (such as a slow parameter change) to generate excitable transients, and we discuss the proposed excitability mechanism in the context of stimulation responses in the epileptic cortex.
USDA-ARS?s Scientific Manuscript database
This study examines the impact of a sloping base on the movement of transients through groundwater systems. Dimensionless variables and regression of model results are employed to develop functions relating the transient change in saturated thickness to the distance upgradient and downgradient from ...
Effects of Activation Energy to Transient Response of Semiconductor Gas Sensor
NASA Astrophysics Data System (ADS)
Fujimoto, Akira; Ohtani, Tatsuki
The smell classifiable gas sensor will be desired for many applications such as gas detection alarms, process controls for food production and so on. We have tried to realize the sensor using transient responses of semiconductor gas sensor consisting of tin dioxide and pointed out that the sensor gave us different transient responses for kinds of gas. Results of model calculation showed the activation energy of chemical reaction on the sensor surface strongly depended on the transient response. We tried to estimate the activation energies by molecular orbital calculation with SnO2 Cluster. The results show that there is a liner relationship between the gradient of the transient responses and activation energies for carboxylic and alcoholic gases. Transient response will be predicted from activation energy in the same kind of gas and the smell discrimination by single semiconductor gas sensor will be realized by this relationship.
NASA Astrophysics Data System (ADS)
Raffray, A. René; Federici, Gianfranco
1997-04-01
RACLETTE (Rate Analysis Code for pLasma Energy Transfer Transient Evaluation), a comprehensive but relatively simple and versatile model, was developed to help in the design analysis of plasma facing components (PFCs) under 'slow' high power transients, such as those associated with plasma vertical displacement events. The model includes all the key surface heat transfer processes such as evaporation, melting, and radiation, and their interaction with the PFC block thermal response and the coolant behaviour. This paper represents part I of two sister and complementary papers. It covers the model description, calibration and validation, and presents a number of parametric analyses shedding light on and identifying trends in the PFC armour block response to high plasma energy deposition transients. Parameters investigated include the plasma energy density and deposition time, the armour thickness and the presence of vapour shielding effects. Part II of the paper focuses on specific design analyses of ITER plasma facing components (divertor, limiter, primary first wall and baffle), including improvements in the thermal-hydraulic modeling required for better understanding the consequences of high energy deposition transients in particular for the ITER limiter case.
Model of the transient neurovascular response based on prompt arterial dilation
Kim, Jung Hwan; Khan, Reswanul; Thompson, Jeffrey K; Ress, David
2013-01-01
Brief neural stimulation results in a stereotypical pattern of vascular and metabolic response that is the basis for popular brain-imaging methods such as functional magnetic resonance imagine. However, the mechanisms of transient oxygen transport and its coupling to cerebral blood flow (CBF) and oxygen metabolism (CMRO2) are poorly understood. Recent experiments show that brief stimulation produces prompt arterial vasodilation rather than venous vasodilation. This work provides a neurovascular response model for brief stimulation based on transient arterial effects using one-dimensional convection–diffusion transport. Hemoglobin oxygen dissociation is included to enable predictions of absolute oxygen concentrations. Arterial CBF response is modeled using a lumped linear flow model, and CMRO2 response is modeled using a gamma function. Using six parameters, the model successfully fit 161/166 measured extravascular oxygen time courses obtained for brief visual stimulation in cat cerebral cortex. Results show how CBF and CMRO2 responses compete to produce the observed features of the hemodynamic response: initial dip, hyperoxic peak, undershoot, and ringing. Predicted CBF and CMRO2 response amplitudes are consistent with experimental measurements. This model provides a powerful framework to quantitatively interpret oxygen transport in the brain; in particular, its intravascular oxygen concentration predictions provide a new model for fMRI responses. PMID:23756690
NASA Astrophysics Data System (ADS)
Chang, Jiang-Hao; Yu, Jing-Cun; Liu, Zhi-Xin
2016-09-01
The full-space transient electromagnetic response of water-filled goaves in coal mines were numerically modeled. Traditional numerical modeling methods cannot be used to simulate the underground full-space transient electromagnetic field. We used multiple transmitting loops instead of the traditional single transmitting loop to load the transmitting loop into Cartesian grids. We improved the method for calculating the z-component of the magnetic field based on the characteristics of full space. Then, we established the fullspace 3D geoelectrical model using geological data for coalmines. In addition, the transient electromagnetic responses of water-filled goaves of variable shape at different locations were simulated by using the finite-difference time-domain (FDTD) method. Moreover, we evaluated the apparent resistivity results. The numerical modeling results suggested that the resistivity differences between the coal seam and its roof and floor greatly affect the distribution of apparent resistivity, resulting in nearly circular contours with the roadway head at the center. The actual distribution of apparent resistivity for different geoelectrical models of water in goaves was consistent with the models. However, when the goaf water was located in one side, a false low-resistivity anomaly would appear on the other side owing to the full-space effect but the response was much weaker. Finally, the modeling results were subsequently confirmed by drilling, suggesting that the proposed method was effective.
Nonlinear transient analysis of multi-mass flexible rotors - theory and applications
NASA Technical Reports Server (NTRS)
Kirk, R. G.; Gunter, E. J.
1973-01-01
The equations of motion necessary to compute the transient response of multi-mass flexible rotors are formulated to include unbalance, rotor acceleration, and flexible damped nonlinear bearing stations. A method of calculating the unbalance response of flexible rotors from a modified Myklestad-Prohl technique is discussed in connection with the method of solution for the transient response. Several special cases of simplified rotor-bearing systems are presented and analyzed for steady-state response, stability, and transient behavior. These simplified rotor models produce extensive design information necessary to insure stable performance to elastic mounted rotor-bearing systems under varying levels and forms of excitation. The nonlinear journal bearing force expressions derived from the short bearing approximation are utilized in the study of the stability and transient response of the floating bush squeeze damper support system. Both rigid and flexible rotor models are studied, and results indicate that the stability of flexible rotors supported by journal bearings can be greatly improved by the use of squeeze damper supports. Results from linearized stability studies of flexible rotors indicate that a tuned support system can greatly improve the performance of the units from the standpoint of unbalanced response and impact loading. Extensive stability and design charts may be readily produced for given rotor specifications by the computer codes presented in this analysis.
Cui, Haoyang; Xu, Yongpeng; Yang, Junjie; Tang, Naiyun; Tang, Zhong
2013-01-01
The transient photovoltaic (PV) characteristic of HgCdTe PV array is studied using an ultrafast laser. The photoresponse shows an apparent negative valley first, then it evolves into a positive peak. By employing a combined theoretical model of pn junction and Schottky potential, this photo-response polarity changing curves can be interpreted well. An obvious decreasing of ratio of negative valley to positive peak can be realized by limiting the illumination area of the array electrode. This shows that the photoelectric effect of Schottky barrier at metal-semiconductor (M/S) interface is suppressed, which will verify the correctness of the model. The characteristic parameters of transient photo-response induced from p-n junction and Schottky potential are extracted by fitting the response curve utilizing this model. It shows that the negative PV response induced by the Schottky barrier decreases the positive photovoltage generated by the pn junction. PMID:24194676
Cui, Haoyang; Xu, Yongpeng; Yang, Junjie; Tang, Naiyun; Tang, Zhong
2013-01-01
The transient photovoltaic (PV) characteristic of HgCdTe PV array is studied using an ultrafast laser. The photoresponse shows an apparent negative valley first, then it evolves into a positive peak. By employing a combined theoretical model of pn junction and Schottky potential, this photo-response polarity changing curves can be interpreted well. An obvious decreasing of ratio of negative valley to positive peak can be realized by limiting the illumination area of the array electrode. This shows that the photoelectric effect of Schottky barrier at metal-semiconductor (M/S) interface is suppressed, which will verify the correctness of the model. The characteristic parameters of transient photo-response induced from p-n junction and Schottky potential are extracted by fitting the response curve utilizing this model. It shows that the negative PV response induced by the Schottky barrier decreases the positive photovoltage generated by the pn junction.
NASA Technical Reports Server (NTRS)
O'Connor, Brian; Hernandez, Deborah; Hornsby, Linda; Brown, Maria; Horton-Mullins, Kathryn
2017-01-01
Outline: Background of ISS (International Space Station) Material Science Research Rack; NASA SCA (Sample Cartridge Assembly) Design; GEDS (Gravitational Effects in Distortion in Sintering) Experiment Ampoule Design; Development Testing Summary; Thermal Modeling and Analysis. Summary: GEDS design development challenging (GEDS Ampoule design developed through MUGS (Microgravity) testing; Short duration transient sample processing; Unable to measure sample temperatures); MUGS Development testing used to gather data (Actual LGF (Low Gradient Furnace)-like furnace response; Provided sample for sintering evaluation); Transient thermal model integral to successful GEDS experiment (Development testing provided furnace response; PI (Performance Indicator) evaluation of sintering anchored model evaluation of processing durations; Thermal transient model used to determine flight SCA sample processing profiles).
NASA Technical Reports Server (NTRS)
Mahan, J. R.; Kowsary, F.; Tira, N.; Gardiner, B. D.
1987-01-01
A NASA-developed finite element-based model of a generic active cavity radiometer (ACR) has been developed in order to study the dependence on operating temperature of the closed-loop and open-loop transient response of the instrument. Transient conduction within the sensing element is explored, and the transient temperature distribution resulting from the application of a time-varying radiative boundary condition is calculated. The results verify the prediction that operation of an ACR at cryogenic temperatures results in large gains in frequency response.
Transient response of sap flow to wind speed.
Chu, Chia R; Hsieh, Cheng-I; Wu, Shen-Yuang; Phillips, Nathan G
2009-01-01
Transient responses of sap flow to step changes in wind speed were experimentally investigated in a wind tunnel. A Granier-type sap flow sensor was calibrated and tested in a cylindrical tube for analysis of its transient time response. Then the sensor was used to measure the transient response of a well-watered Pachira macrocarpa plant to wind speed variations. The transient response of sap flow was described using the resistance-capacitance model. The steady sap flow rate increased as the wind speed increased at low wind speeds. Once the wind speed exceeded 8.0 m s(-1), the steady sap flow rate did not increase further. The transpiration rate, measured gravimetrically, showed a similar trend. The response of nocturnal sap flow to wind speed variation was also measured and compared with the results in the daytime. Under the same wind speed, the steady sap flow rate was smaller than that in the daytime, indicating differences between diurnal and nocturnal hydraulic function, and incomplete stomatal closure at night. In addition, it was found that the temporal response of the Granier sensor is fast enough to resolve the transient behaviour of water flux in plant tissue.
Transient responses of phosphoric acid fuel cell power plant system. Ph.D. Thesis
NASA Technical Reports Server (NTRS)
Lu, Cheng-Yi
1983-01-01
An analytical and computerized study of the steady state and transient response of a phosphoric acid fuel cell (PAFC) system was completed. Parametric studies and sensitivity analyses of the PAFC system's operation were accomplished. Four non-linear dynamic models of the fuel cell stack, reformer, shift converters, and heat exchangers were developed based on nonhomogeneous non-linear partial differential equations, which include the material, component, energy balance, and electrochemical kinetic features. Due to a lack of experimental data for the dynamic response of the components only the steady state results were compared with data from other sources, indicating reasonably good agreement. A steady state simulation of the entire system was developed using, nonlinear ordinary differential equations. The finite difference method and trial-and-error procedures were used to obtain a solution. Using the model, a PAFC system, that was developed under NASA Grant, NCC3-17, was improved through the optimization of the heat exchanger network. Three types of cooling configurations for cell plates were evaluated to obtain the best current density and temperature distributions. The steady state solutions were used as the initial conditions in the dynamic model. The transient response of a simplified PAFC system, which included all of the major components, subjected to a load change was obtained. Due to the length of the computation time for the transient response calculations, analysis on a real-time computer was not possible. A simulation of the real-time calculations was developed on a batch type computer. The transient response characteristics are needed for the optimization of the design and control of the whole PAFC system. All of the models, procedures and simulations were programmed in Fortran and run on IBM 370 computers at Cleveland State University and the NASA Lewis Research Center.
Electrically-Assisted Turbocharger Development for Performance and Emissions
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bailey, Milton
2000-08-20
Turbocharger transient lag inherently imposes a tradeoff between a robust engine response to transient load shifts and exhaust emissions. By itself, a well matched turbocharger for an engine has limited flexibility in improving this transient response. Electrically-assisted turbocharging has been seen as an attractive option to improve response and lower transient emissions. This paper presents the results of a multi-year joint CRADA between DDC and ORNL. Virtual lab diesel simulation models characterized the performance improvement potential of an electrically assisted turbocharger technology. Operating requirements to reduce transient duration between load shift time by up to 50% were determined. A turbomachinemore » has been conceptualized with an integrated motor-generator, providing transient burst boost plus energy recovery capability. Numerous electric motor designs were considered, and a prototype motor was developed, fabricated, and is undergoing tests. Power controls have been designed and fabricated.« less
Transient behavior of redox flow battery connected to circuit based on global phase structure
NASA Astrophysics Data System (ADS)
Mannari, Toko; Hikihara, Takashi
A Redox Flow Battery (RFB) is one of the promising energy storage systems in power grid. An RFB has many advantages such as a quick response, a large capacity, and a scalability. Due to these advantages, an RFB can operate in mixed time scale. Actually, it has been demonstrated that an RFB can be used for load leveling, compensating sag, and smoothing the output of the renewable sources. An analysis on transient behaviors of an RFB is a key issue for these applications. An RFB is governed by electrical, chemical, and fluid dynamics. The hybrid structure makes the analysis difficult. To analyze transient behaviors of an RFB, the exact model is necessary. In this paper, we focus on a change in a concentration of ions in the electrolyte, and simulate the change with a model which is mainly based on chemical kinetics. The simulation results introduces transient behaviors of an RFB in a response to a load variation. There are found three kinds of typical transient behaviors including oscillations. As results, it is clarified that the complex transient behaviors, due to slow and fast dynamics in the system, arise by the quick response to load.
Thermal modelling and control of 130kw direct contact (salt/air) heat exchanger
NASA Astrophysics Data System (ADS)
Qureshi, Omer A.; Calvet, Nicolas; Armstrong, Peter R.
2017-06-01
This work investigates the transient response of a certain type of direct contact heat exchanger (DCHX) that consists of packing (Raschig Rings) to increase the surface area for effective heat transfer between molten salt and air. Molten salt from the hot tank enters the heat exchanger (HX) and exit after heating the air still in the molten form. Thermal capacitance of the HX, mainly due to packing and resident salt inside the HX, results in strong transient response. Pure delay from salt residence time may also impact transient response. Both phenomena have been modelled in this paper. A Proportional-Integral controller (PI control) performance has been evaluated to maintain the minimum salt temperature above avoid crystallization temperature of the salt.
Transient Response of a PEM Fuel Cell Representing Variable Load for a Moving Vehicle on Urban Roads
DOT National Transportation Integrated Search
2001-01-01
Three-dimensional numerical simulation of transient response of a Polymer Electrolyte Membrane (PEM) fuel cell subjected to a variable load is developed. The model parameters are typical of experimental cell for a 10-cm2 reactive area with serpentine...
Enhancing photocurrent transient spectroscopy by electromagnetic modeling.
Diesinger, H; Panahandeh-Fard, M; Wang, Z; Baillargeat, D; Soci, C
2012-05-01
The shape and duration of photocurrent transients generated by a photoconductive switch depend on both the intrinsic response of the active material and the geometry of the transmission line structure. The present electromagnetic model decouples both shape forming contributions. In contrast to previously published work, it accounts for the particular operating mode of transient spectroscopy. The objective is to increase the time resolution by two approaches, by optimizing structural response and by deconvolving it from experimental data. The switch structure is represented by an effective transimpedance onto which the active material acts as current generator. As proof of concept, the response of a standard microstrip switch is modeled and deconvolved from experimental data acquired in GaAs, yielding a single exponential material response and hence supporting the validity of the approach. Beyond compensating for the response deterioration by the structure, switch architectures can be a priori optimized with respect to frequency response. As an example, it is shown that a microstrip gap that can be deposited on materials incompatible with standard lithography reduces pulse broadening by an order of magnitude if it is provided with transitions to coplanar access lines.
Modeling of environmentally induced transients within satellites
NASA Technical Reports Server (NTRS)
Stevens, N. John; Barbay, Gordon J.; Jones, Michael R.; Viswanathan, R.
1987-01-01
A technique is described that allows an estimation of possible spacecraft charging hazards. This technique, called SCREENS (spacecraft response to environments of space), utilizes the NASA charging analyzer program (NASCAP) to estimate the electrical stress locations and the charge stored in the dielectric coatings due to spacecraft encounter with a geomagnetic substorm environment. This information can then be used to determine the response of the spacecraft electrical system to a surface discharge by means of lumped element models. The coupling into the electronics is assumed to be due to magnetic linkage from the transient currents flowing as a result of the discharge transient. The behavior of a spinning spacecraft encountering a severe substorm is predicted using this technique. It is found that systems are potentially vulnerable to upset if transient signals enter through the ground lines.
A novel approach to model the transient behavior of solid-oxide fuel cell stacks
NASA Astrophysics Data System (ADS)
Menon, Vikram; Janardhanan, Vinod M.; Tischer, Steffen; Deutschmann, Olaf
2012-09-01
This paper presents a novel approach to model the transient behavior of solid-oxide fuel cell (SOFC) stacks in two and three dimensions. A hierarchical model is developed by decoupling the temperature of the solid phase from the fluid phase. The solution of the temperature field is considered as an elliptic problem, while each channel within the stack is modeled as a marching problem. This paper presents the numerical model and cluster algorithm for coupling between the solid phase and fluid phase. For demonstration purposes, results are presented for a stack operated on pre-reformed hydrocarbon fuel. Transient response to load changes is studied by introducing step changes in cell potential and current. Furthermore, the effect of boundary conditions and stack materials on response time and internal temperature distribution is investigated.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kleidon, Alex; Kravitz, Benjamin S.; Renner, Maik
2015-01-16
We derive analytic expressions of the transient response of the hydrological cycle to surface warming from an extremely simple energy balance model in which turbulent heat fluxes are constrained by the thermodynamic limit of maximum power. For a given magnitude of steady-state temperature change, this approach predicts the transient response as well as the steady-state change in surface energy partitioning and the hydrologic cycle. We show that the transient behavior of the simple model as well as the steady state hydrological sensitivities to greenhouse warming and solar geoengineering are comparable to results from simulations using highly complex models. Many ofmore » the global-scale hydrological cycle changes can be understood from a surface energy balance perspective, and our thermodynamically-constrained approach provides a physically robust way of estimating global hydrological changes in response to altered radiative forcing.« less
Nonthermal response of YBa2Cu3O7-δ thin films to picosecond THz pulses
NASA Astrophysics Data System (ADS)
Probst, P.; Semenov, A.; Ries, M.; Hoehl, A.; Rieger, P.; Scheuring, A.; Judin, V.; Wünsch, S.; Il'in, K.; Smale, N.; Mathis, Y.-L.; Müller, R.; Ulm, G.; Wüstefeld, G.; Hübers, H.-W.; Hänisch, J.; Holzapfel, B.; Siegel, M.; Müller, A.-S.
2012-05-01
The photoresponse of YBa2Cu3O7-δ thin film microbridges with thicknesses between 15 and 50 nm was studied in the optical and terahertz frequency range. The voltage transients in response to short radiation pulses were recorded in real time with a resolution of a few tens of picoseconds. The bridges were excited by either femtosecond pulses at a wavelength of 0.8 μm or broadband (0.1-1.5 THz) picosecond pulses of coherent synchrotron radiation. The transients in response to optical radiation are qualitatively well explained in the framework of the two-temperature model with a fast component in the picosecond range and a bolometric nanosecond component whose decay time depends on the film thickness. The transients in the THz regime showed no bolometric component and had amplitudes up to three orders of magnitude larger than the two-temperature model predicts. Additionally THz field-dependent transients in the absence of DC bias were observed. We attribute the response in the THz regime to a rearrangement of vortices caused by high-frequency currents.
Transient Simulation of Last Deglaciation with a New Mechanism for B lling-Aller d Warming
DOE Office of Scientific and Technical Information (OSTI.GOV)
Erickson, David J
2009-01-01
We conducted the first synchronously coupled atmosphere-ocean general circulation model simulation from the Last Glacial Maximum to the Boelling-Alleroed (BA) warming. Our model reproduces several major features of the deglacial climate evolution, suggesting a good agreement in climate sensitivity between the model and observations. In particular, our model simulates the abrupt BA warming as a transient response of the Atlantic meridional overturning circulation (AMOC) to a sudden termination of freshwater discharge to the North Atlantic before the BA. In contrast to previous mechanisms that invoke AMOC multiple equilibrium and Southern Hemisphere climate forcing, we propose that the BA transition ismore » caused by the superposition of climatic responses to the transient CO{sub 2} forcing, the AMOC recovery from Heinrich Event 1, and an AMOC overshoot.« less
Nonlinear dynamic analysis of traveling wave-type ultrasonic motors.
Nakagawa, Yosuke; Saito, Akira; Maeno, Takashi
2008-03-01
In this paper, nonlinear dynamic response of a traveling wave-type ultrasonic motor was investigated. In particular, understanding the transient dynamics of a bar-type ultrasonic motor, such as starting up and stopping, is of primary interest. First, the transient response of the bar-type ultrasonic motor at starting up and stopping was measured using a laser Doppler velocimeter, and its driving characteristics are discussed in detail. The motor is shown to possess amplitude-dependent nonlinearity that greatly influences the transient dynamics of the motor. Second, a dynamical model of the motor was constructed as a second-order nonlinear oscillator, which represents the dynamics of the piezoelectric ceramic, stator, and rotor. The model features nonlinearities caused by the frictional interface between the stator and the rotor, and cubic nonlinearity in the dynamics of the stator. Coulomb's friction model was employed for the interface model, and a stick-slip phenomenon is considered. Lastly, it was shown that the model is capable of representing the transient dynamics of the motor accurately. The critical parameters in the model were identified from measured results, and numerical simulations were conducted using the model with the identified parameters. Good agreement between the results of measurements and numerical simulations is observed.
NASA Astrophysics Data System (ADS)
Matussek, Robert; Dzienis, Cezary; Blumschein, Jörg; Schulte, Horst
2014-12-01
In this paper, a generic enhanced protection current transformer (CT) model with saturation effects and transient behavior is presented. The model is used for the purpose of analysis and design of power system protection algorithms. Three major classes of protection CT have been modeled which all take into account the nonlinear inductance with remanence effects. The transient short-circuit currents in power systems are simulated under CT saturation condition. The response of a common power system protection algorithm with respect to robustness to nominal parameter variations and sensitivity against maloperation is demonstrated by simulation studies.
Transients control in Raman fiber amplifiers
NASA Astrophysics Data System (ADS)
Freitas, Marcio; Givigi, Sidney N., Jr.; Klein, Jackson; Calmon, Luiz C.; de Almeida, Ailson R.
2004-11-01
Raman fiber amplifiers (RFA) are being used in optical transmission communication systems in the recent years due to their advantages in comparison to erbium-doped fiber amplifiers (EDFA). Recently the analysis of RFAs dynamic response and transients control has become important in order to predict the system response to add/drop of channels or cable cuts in optical systems, and avoid impairments caused by the power transients. Fast signal power transients in the surviving channels are caused by the cross-gain saturation effect in RFA and the slope of the gain saturation characteristics determines the steady-state surviving channel power excursion. We are presenting the modeling and analysis of power transients and its control using a pump control method for a single and multi-pump scheme.
Nonstationary Transient Vibroacoustic Response of a Beam Structure
NASA Technical Reports Server (NTRS)
Caimi, R. E.; Margasahayam, R. N.; Nayfeh, Jamal F.
1997-01-01
This study consists of an investigation into the nonstationary transient response of the Verification Test Article (VETA) when subjected to random acoustic excitation. The goal is to assess excitation models that can be used in the design of structures and equipment when knowledge of the structure and the excitation is limited. The VETA is an instrumented cantilever beam that was exposed to acoustic loading during five Space Shuttle launches. The VETA analytical structural model response is estimated using the direct averaged power spectral density and the normalized pressure spectra methods. The estimated responses are compared to the measured response of the VETA. These comparisons are discussed with a focus on prediction conservatism and current design practice.
NASA Technical Reports Server (NTRS)
Delp, P.; Crossman, E. R. F. W.; Szostak, H.
1972-01-01
The automobile-driver describing function for lateral position control was estimated for three subjects from frequency response analysis of straight road test results. The measurement procedure employed an instrumented full size sedan with known steering response characteristics, and equipped with a lateral lane position measuring device based on video detection of white stripe lane markings. Forcing functions were inserted through a servo driven double steering wheel coupling the driver to the steering system proper. Random appearing, Gaussian, and transient time functions were used. The quasi-linear models fitted to the random appearing input frequency response characterized the driver as compensating for lateral position error in a proportional, derivative, and integral manner. Similar parameters were fitted to the Gabor transformed frequency response of the driver to transient functions. A fourth term corresponding to response to lateral acceleration was determined by matching the time response histories of the model to the experimental results. The time histories show evidence of pulse-like nonlinear behavior during extended response to step transients which appear as high frequency remnant power.
Shu, Hongying; Wang, Lin; Watmough, James
2014-01-01
Sustained and transient oscillations are frequently observed in clinical data for immune responses in viral infections such as human immunodeficiency virus, hepatitis B virus, and hepatitis C virus. To account for these oscillations, we incorporate the time lag needed for the expansion of immune cells into an immunosuppressive infection model. It is shown that the delayed antiviral immune response can induce sustained periodic oscillations, transient oscillations and even sustained aperiodic oscillations (chaos). Both local and global Hopf bifurcation theorems are applied to show the existence of periodic solutions, which are illustrated by bifurcation diagrams and numerical simulations. Two types of bistability are shown to be possible: (i) a stable equilibrium can coexist with another stable equilibrium, and (ii) a stable equilibrium can coexist with a stable periodic solution.
Sensitivity analysis of reactive ecological dynamics.
Verdy, Ariane; Caswell, Hal
2008-08-01
Ecological systems with asymptotically stable equilibria may exhibit significant transient dynamics following perturbations. In some cases, these transient dynamics include the possibility of excursions away from the equilibrium before the eventual return; systems that exhibit such amplification of perturbations are called reactive. Reactivity is a common property of ecological systems, and the amplification can be large and long-lasting. The transient response of a reactive ecosystem depends on the parameters of the underlying model. To investigate this dependence, we develop sensitivity analyses for indices of transient dynamics (reactivity, the amplification envelope, and the optimal perturbation) in both continuous- and discrete-time models written in matrix form. The sensitivity calculations require expressions, some of them new, for the derivatives of equilibria, eigenvalues, singular values, and singular vectors, obtained using matrix calculus. Sensitivity analysis provides a quantitative framework for investigating the mechanisms leading to transient growth. We apply the methodology to a predator-prey model and a size-structured food web model. The results suggest predator-driven and prey-driven mechanisms for transient amplification resulting from multispecies interactions.
Organization of extratropical transients during El Nino
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hoerling, M.P.; Ting, Mingfang
Four observed El Nino-Southern Oscillation (ENSO) events are studied to determine the mechanisms responsible for the anomalous extratropical atmospheric circulation during northern winter. A parallel analysis of a GCM's response to El Nino is performed in order to assess if similar mechanisms are operative in the model atmosphere. The observed stationary wave anomalies over the Pacific/North American (PNA) region are found to be similar during the four winters despite appreciable differences in sea surface temperatures. The anomalous transient vorticity fluxes are remarkably robust over the North Pacific during each even, with an eastward extension of the climatological storm track leadingmore » to strong cyclonic forcing near 40[degrees]N, 150[degrees]W. This forcing is in phase with the seasonal mean Aleutian trough anomaly suggesting the important of eddy-mean flow interaction. By comparison, the intersample variability of the GCM response over the PNA region is found to exceed the observed inter-El Nino variability. This stems primarily from a large variability in the model's anomalous transients over the North Pacific. Further analysis reveals that extratropical vorticity transients are the primary mechanism maintaining the stationary wave anomalies over the PNA region during all four observed ENSO winters. In the case of the GCM, the organization of transient eddies is ill defined over the North Pacific, a behavior indicative of model error. A physical model is proposed to explain the robustness of the tropical controlling influence of the extratropical transients in nature. A simple equatorial Pacific heat source directly forces a tropical anticyclone whose phase relative to the climatological tropical anticyclone leads to an eastward extension of the subtropical jet stream. This mechanism appears to be equally effective for a heat source located either in the central or eastern Pacific basin. 36 refs., 14 figs.« less
What Climate Sensitivity Index Is Most Useful for Projections?
NASA Astrophysics Data System (ADS)
Grose, Michael R.; Gregory, Jonathan; Colman, Robert; Andrews, Timothy
2018-02-01
Transient climate response (TCR), transient response at 140 years (T140), and equilibrium climate sensitivity (ECS) indices are intended as benchmarks for comparing the magnitude of climate response projected by climate models. It is generally assumed that TCR or T140 would explain more variability between models than ECS for temperature change over the 21st century, since this timescale is the realm of transient climate change. Here we find that TCR explains more variability across Coupled Model Intercomparison Project phase 5 than ECS for global temperature change since preindustrial, for 50 or 100 year global trends up to the present, and for projected change under representative concentration pathways in regions of delayed warming such as the Southern Ocean. However, unexpectedly, we find that ECS correlates higher than TCR for projected change from the present in the global mean and in most regions. This higher correlation does not relate to aerosol forcing, and the physical cause requires further investigation.
NASA Technical Reports Server (NTRS)
Li, Peng; Chou, Ming-Dah; Arking, Albert
1987-01-01
The transient response of the climate to increasing CO2 is studied using a modified version of the multilayer energy balance model of Peng et al. (1982). The main characteristics of the model are described. Latitudinal and seasonal distributions of planetary albedo, latitude-time distributions of zonal mean temperatures, and latitudinal distributions of evaporation, water vapor transport, and snow cover generated from the model and derived from actual observations are analyzed and compared. It is observed that in response to an atmospheric doubling of CO2, the model reaches within 1/e of the equilibrium response of global mean surface temperature in 9-35 years for the probable range of vertical heat diffusivity in the ocean. For CO2 increases projected by the National Research Council (1983), the model's transient response in annually and globally averaged surface temperatures is 60-75 percent of the corresponding equilibrium response, and the disequilibrium increases with increasing heat diffusivity of the ocean.
Efficient multidimensional regularization for Volterra series estimation
NASA Astrophysics Data System (ADS)
Birpoutsoukis, Georgios; Csurcsia, Péter Zoltán; Schoukens, Johan
2018-05-01
This paper presents an efficient nonparametric time domain nonlinear system identification method. It is shown how truncated Volterra series models can be efficiently estimated without the need of long, transient-free measurements. The method is a novel extension of the regularization methods that have been developed for impulse response estimates of linear time invariant systems. To avoid the excessive memory needs in case of long measurements or large number of estimated parameters, a practical gradient-based estimation method is also provided, leading to the same numerical results as the proposed Volterra estimation method. Moreover, the transient effects in the simulated output are removed by a special regularization method based on the novel ideas of transient removal for Linear Time-Varying (LTV) systems. Combining the proposed methodologies, the nonparametric Volterra models of the cascaded water tanks benchmark are presented in this paper. The results for different scenarios varying from a simple Finite Impulse Response (FIR) model to a 3rd degree Volterra series with and without transient removal are compared and studied. It is clear that the obtained models capture the system dynamics when tested on a validation dataset, and their performance is comparable with the white-box (physical) models.
Doidy, Joan; Li, Ying; Neymotin, Benjamin; Edwards, Molly B; Varala, Kranthi; Gresham, David; Coruzzi, Gloria M
2016-02-03
Dynamic transcriptional regulation is critical for an organism's response to environmental signals and yet remains elusive to capture. Such transcriptional regulation is mediated by master transcription factors (TF) that control large gene regulatory networks. Recently, we described a dynamic mode of TF regulation named "hit-and-run". This model proposes that master TF can interact transiently with a set of targets, but the transcription of these transient targets continues after the TF dissociation from the target promoter. However, experimental evidence validating active transcription of the transient TF-targets is still lacking. Here, we show that active transcription continues after transient TF-target interactions by tracking de novo synthesis of RNAs made in response to TF nuclear import. To do this, we introduced an affinity-labeled 4-thiouracil (4tU) nucleobase to specifically isolate newly synthesized transcripts following conditional TF nuclear import. Thus, we extended the TARGET system (Transient Assay Reporting Genome-wide Effects of Transcription factors) to include 4tU-labeling and named this new technology TARGET-tU. Our proof-of-principle example is the master TF Basic Leucine Zipper 1 (bZIP1), a central integrator of metabolic signaling in plants. Using TARGET-tU, we captured newly synthesized mRNAs made in response to bZIP1 nuclear import at a time when bZIP1 is no longer detectably bound to its target. Thus, the analysis of de novo transcripomics demonstrates that bZIP1 may act as a catalyst TF to initiate a transcriptional complex ("hit"), after which active transcription by RNA polymerase continues without the TF being bound to the gene promoter ("run"). Our findings provide experimental proof for active transcription of transient TF-targets supporting a "hit-and-run" mode of action. This dynamic regulatory model allows a master TF to catalytically propagate rapid and broad transcriptional responses to changes in environment. Thus, the functional read-out of de novo transcripts produced by transient TF-target interactions allowed us to capture new models for genome-wide transcriptional control.
On the feasibility of a transient dynamic design analysis
NASA Astrophysics Data System (ADS)
Cunniff, Patrick F.; Pohland, Robert D.
1993-05-01
The Dynamic Design Analysis Method has been used for the past 30 years as part of the Navy's efforts to shock-harden heavy shipboard equipment. This method which has been validated several times employs normal mode theory and design shock values. This report examines the degree of success that may be achieved by using simple equipment-vehicle models that produce time history responses which are equivalent to the responses that would be achieved using spectral design values employed by the Dynamic Design Analysis Method. These transient models are constructed by attaching the equipment's modal oscillators to the vehicle which is composed of rigid masses and elastic springs. Two methods have been developed for constructing these transient models. Each method generates the parameters of the vehicles so as to approximate the required damaging effects, such that the transient model is excited by an idealized impulse applied to the vehicle mass to which the equipment modal oscillators are attached. The first method called the Direct Modeling Method, is limited to equipment with at most three-degrees of freedom and the vehicle consists of a single lumped mass and spring. The Optimization Modeling Method, which is based on the simplex method for optimization, has been used successfully with a variety of vehicle models and equipment sizes.
NASA Astrophysics Data System (ADS)
Crowther, Ashley R.; Singh, Rajendra; Zhang, Nong; Chapman, Chris
2007-10-01
Impulsive responses in geared systems with multiple clearances are studied when the mean torque excitation and system load change abruptly, with application to a vehicle driveline with an automatic transmission. First, torsional lumped-mass models of the planetary and differential gear sets are formulated using matrix elements. The model is then reduced to address tractable nonlinear problems while successfully retaining the main modes of interest. Second, numerical simulations for the nonlinear model are performed for transient conditions and a typical driving situation that induces an impulsive behaviour simulated. However, initial conditions and excitation and load profiles have to be carefully defined before the model can be numerically solved. It is shown that the impacts within the planetary or differential gears may occur under combinations of engine, braking and vehicle load transients. Our analysis shows that the shaping of the engine transient by the torque converter before reaching the clearance locations is more critical. Third, a free vibration experiment is developed for an analogous driveline with multiple clearances and three experiments that excite different response regimes have been carried out. Good correlations validate the proposed methodology.
Transient water stress in a vegetation canopy - Simulations and measurements
NASA Technical Reports Server (NTRS)
Carlson, Toby N.; Belles, James E.; Gillies, Robert R.
1991-01-01
Consideration is given to observational and modeling evidence of transient water stress, the effects of the transpiration plateau on the canopy radiometric temperature, and the factors responsible for the onset of the transpiration plateau, such as soil moisture. Attention is also given to the point at which the transient stress can be detected by remote measurement of surface temperature.
The design of a turboshaft speed governor using modern control techniques
NASA Technical Reports Server (NTRS)
Delosreyes, G.; Gouchoe, D. R.
1986-01-01
The objectives of this program were: to verify the model of off schedule compressor variable geometry in the T700 turboshaft engine nonlinear model; to evaluate the use of the pseudo-random binary noise (PRBN) technique for obtaining engine frequency response data; and to design a high performance power turbine speed governor using modern control methods. Reduction of T700 engine test data generated at NASA-Lewis indicated that the off schedule variable geometry effects were accurate as modeled. Analysis also showed that the PRBN technique combined with the maximum likelihood model identification method produced a Bode frequency response that was as accurate as the response obtained from standard sinewave testing methods. The frequency response verified the accuracy of linear models consisting of engine partial derivatives and used for design. A power turbine governor was designed using the Linear Quadratic Regulator (LQR) method of full state feedback control. A Kalman filter observer was used to estimate helicopter main rotor blade velocity. Compared to the baseline T700 power turbine speed governor, the LQR governor reduced droop up to 25 percent for a 490 shaft horsepower transient in 0.1 sec simulating a wind gust, and up to 85 percent for a 700 shaft horsepower transient in 0.5 sec simulating a large collective pitch angle transient.
Transient Response in a Dendritic Neuron Model for Current Injected at One Branch
Rinzel, John; Rall, Wilfrid
1974-01-01
Mathematical expressions are obtained for the response function corresponding to an instantaneous pulse of current injected to a single dendritic branch in a branched dendritic neuron model. The theoretical model assumes passive membrane properties and the equivalent cylinder constraint on branch diameters. The response function when used in a convolution formula enables one to compute the voltage transient at any specified point in the dendritic tree for an arbitrary current injection at a given input location. A particular numerical example, for a brief current injection at a branch terminal, illustrates the attenuation and delay characteristics of the depolarization peak as it spreads throughout the neuron model. In contrast to the severe attenuation of voltage transients from branch input sites to the soma, the fraction of total input charge actually delivered to the soma and other trees is calculated to be about one-half. This fraction is independent of the input time course. Other numerical examples, which compare a branch terminal input site with a soma input site, demonstrate that, for a given transient current injection, the peak depolarization is not proportional to the input resistance at the injection site and, for a given synaptic conductance transient, the effective synaptic driving potential can be significantly reduced, resulting in less synaptic current flow and charge, for a branch input site. Also, for the synaptic case, the two inputs are compared on the basis of the excitatory post-synaptic potential (EPSP) seen at the soma and the total charge delivered to the soma. PMID:4424185
Robust Adaptive Control Using a Filtering Action
2009-09-01
research performed on this class of control systems , sensitivity to external disturbances and modeling errors together with poor transient response...dissertation, we address the problems of designing a class of Adaptive Control systems which yield fast adaptation, thus good transient response, and...unable to stabilize the system . Although this approach requires more knowledge about the system in order to control it, it is still attractive in cases
Generalized hydromechanical model for stomatal responses to hydraulic perturbations.
Kwon, H W; Choi, M Y
2014-01-07
Stomata respond in a common pattern to various hydraulic perturbations on any part of the 'soil-plant-air' system: initial transient 'wrong-way' responses and final stationary 'right-way' responses. In order to describe this pattern on the basis of statistical physics, we propose a simple model where turgor pressure of a cell is taken to be a power function of its volume, and obtain results in qualitative agreement with experimental data for responses to a variety of hydraulic perturbations: Firstly, stationary stomatal conductance as a function of the vapor pressure deficit divides into three regimes characterized by sensitivities of the stomatal conductance and the transpiration rate with respect to vapor pressure deficit; secondly, for every hydraulic perturbation, the initial transient 'wrong-way' responses always appear; thirdly, on condition that water is supplied insufficiently, stomatal oscillations are often observed; finally, stomatal responses following leaf excision exhibit, after the initial transient wrong-way responses, slow relaxation to stomatal closing. In particular, comparison of areoles having different numbers of stomata demonstrates that areoles with small numbers of stomata tend to provoke lack of water in the soil as well as in the plant. In addition, our model also describes well dependence of the stomatal conductance on temperature. It may be extended further to describe stomatal responses to other environmental factors such as carbon dioxide, light, and temperature. © 2013 Elsevier Ltd. All rights reserved.
Neural control and transient analysis of the LCL-type resonant converter
NASA Astrophysics Data System (ADS)
Zouggar, S.; Nait Charif, H.; Azizi, M.
2000-07-01
This paper proposes a generalised inverse learning structure to control the LCL converter. A feedforward neural network is trained to act as an inverse model of the LCL converter then both are cascaded such that the composed system results in an identity mapping between desired response and the LCL output voltage. Using the large signal model, we analyse the transient output response of the controlled LCL converter in the case of large variation of the load. The simulation results show the efficiency of using neural networks to regulate the LCL converter.
NASA Technical Reports Server (NTRS)
Witmer, E. A.
1975-01-01
The sheet explosive loading technique (SELT) was employed to obtain elastic-plastic, large-deflection transient and/or permanent strain data on simple well-defined structural specimens and materials: initially-flat 6061-T651 aluminum beams with both ends ideally clamped via integral construction. The SELT loading technique was chosen since it is both convenient and provides forcing function information of small uncertainty. These data will be useful for evaluating pertinent structural response prediction methods. A second objective was to obtain high-quality transient-strain data for a well-defined structural/material model subjected to impact by a rigid body of known mass, impact velocity, and geometry; large-deflection, elastic-plastic transient response conditions are of primary interest. The beam with both ends clamped and a steel sphere as the impacting body were chosen. The steel sphere was launched vertically by explosive propulsion to achieve various desired impact velocities. The sphere/beam impact tests resulted in producing a wide range of structural responses and permanent deformations, including rupture of the beam from excessive structural response in two cases. The transient and permanent strain data as well as the permanent deflection data obtained are of high quality and should be useful for checking and evaluating methods for predicting the responses of simple 2-d structures to fragment (sphere) impact. Transient strain data very close to the point of impact were not obtained over as long a time as desirable because the gage(s) in that region became detached during the transient response.
NASA Astrophysics Data System (ADS)
Phan, Leon L.
The motivation behind this thesis mainly stems from previous work performed at Hispano-Suiza (Safran Group) in the context of the European research project "Power Optimised Aircraft". Extensive testing on the COPPER Bird RTM, a test rig designed to characterize aircraft electrical networks, demonstrated the relevance of transient regimes in the design and development of dynamic systems. Transient regimes experienced by dynamic systems may have severe impacts on the operation of the aircraft. For example, the switching on of a high electrical load might cause a network voltage drop inducing a loss of power available to critical aircraft systems. These transient behaviors are thus often regulated by dynamic constraints, requiring the dynamic signals to remain within bounds whose values vary with time. The verification of these peculiar types of constraints, which generally requires high-fidelity time-domain simulation, intervenes late in the system development process, thus potentially causing costly design iterations. The research objective of this thesis is to develop a methodology that integrates the verification of dynamic constraints in the early specification of dynamic systems. In order to circumvent the inefficiencies of time-domain simulation, multivariate dynamic surrogate models of the original time-domain simulation models are generated, building on a nonlinear system identification technique using wavelet neural networks (or wavenets), which allow the multiscale nature of transient signals to be captured. However, training multivariate wavenets can become computationally prohibitive as the number of design variables increases. Therefore, an alternate approach is formulated, in which dynamic surrogate models using sigmoid-based neural networks are used to emulate the transient behavior of the envelopes of the time-domain response. Thus, in order to train the neural network, the envelopes are extracted by first separating the scales of the dynamic response, using a multiresolution analysis (MRA) based on the discrete wavelet transform. The MRA separates the dynamic response into a trend and a noise signal (ripple). The envelope of the noise is then computed with a windowing method, and recombined with the trend in order to reconstruct the global envelope of the dynamic response. The run-time efficiency of the resulting dynamic surrogate models enable the implementation of a data farming approach, in which a Monte-Carlo simulation generates time-domain behaviors of transient responses for a vast set of design and operation scenarios spanning the design and operation space. An interactive visualization environment, enabling what-if analyses, will be developed; the user can thereby instantaneously comprehend the transient response of the system (or its envelope) and its sensitivities to design and operation variables, as well as filter the design space to have it exhibit only the design scenarios verifying the dynamic constraints. The proposed methodology, along with its foundational hypotheses, are tested on the design and optimization of a 350VDC network, where a generator and its control system are concurrently designed in order to minimize the electrical losses, while ensuring that the transient undervoltage induced by peak demands in the consumption of a motor does not violate transient power quality constraints.
On the transient dynamics of piezoelectric-based, state-switched systems
NASA Astrophysics Data System (ADS)
Lopp, Garrett K.; Kelley, Christopher R.; Kauffman, Jeffrey L.
2018-01-01
This letter reports on the induced mechanical transients for piezoelectric-based, state-switching approaches utilizing both experimental tests and a numerical model that more accurately captures the dynamics associated with a switch between stiffness states. Currently, switching models instantaneously dissipate the stored piezoelectric voltage, resulting in a discrete change in effective stiffness states and a discontinuity in the system dynamics during the switching event. The proposed model allows for a rapid but continuous voltage dissipation and the corresponding variation between stiffness states, as one sees in physical implementations. This rapid variation in system stiffness when switching at a point of non-zero strain leads to high-frequency, large-amplitude transients in the system acceleration response. Utilizing a fundamental piezoelectric bimorph, a comparison between the numerical and experimental results reveals that these mechanical transients are much stronger than originally anticipated and masked by measurement hardware limitations, thus highlighting the significance of an appropriate system model governing the switch dynamics. Such a model enables designers to analyze systems that incorporate piezoelectric-based state switching with greater accuracy to ensure that these transients do not degrade the intended performance. Finally, if the switching does create unacceptable transients, controlling the duration of voltage dissipation enables control over the frequency content and peak amplitudes associated with the switch-induced acceleration transients.
Calcagno, B; Eyles, D; van Alphen, B; van Swinderen, B
2013-01-08
It has been observed that certain developmental environmental risk factors for schizophrenia when modeled in rodents alter the trajectory of dopaminergic development, leading to persistent behavioural changes in adults. This has recently been articulated as the "dopamine ontogeny hypothesis of schizophrenia". To test one aspect of this hypothesis, namely that transient dopaminergic effects during development modulate attention-like behavior and arousal in adults, we turned to a small-brain model, Drosophila melanogaster. By applying genetic tools allowing transient activation or silencing of dopaminergic neurons in the fly brain, we investigated whether a critical window exists during development when altered dopamine (DA) activity levels could lead to impairments in arousal states in adult animals. We found that increased activity in dopaminergic neurons in later stages of development significantly increased visual responsiveness and locomotion, especially in adult males. This misallocation of visual salience and hyperactivity mimicked the effect of acute methamphetamine feeding to adult flies, suggesting up-regulated DA signaling could result from developmental manipulations. Finally, brain recordings revealed significantly reduced gamma-band activity in adult animals exposed to the transient developmental insult. Together, these data support the idea that transient alterations in DA signaling during development can permanently alter behavior in adults, and that a reductionist model such as Drosophila can be used to investigate potential mechanisms underlying complex cognitive disorders such as schizophrenia.
James, A.L.; McDonnell, Jeffery J.; Tromp-Van Meerveld, I.; Peters, N.E.
2010-01-01
As a fundamental unit of the landscape, hillslopes are studied for their retention and release of water and nutrients across a wide range of ecosystems. The understanding of these near-surface processes is relevant to issues of runoff generation, groundwater-surface water interactions, catchment export of nutrients, dissolved organic carbon, contaminants (e.g. mercury) and ultimately surface water health. We develop a 3-D physics-based representation of the Panola Mountain Research Watershed experimental hillslope using the TOUGH2 sub-surface flow and transport simulator. A recent investigation of sub-surface flow within this experimental hillslope has generated important knowledge of threshold rainfall-runoff response and its relation to patterns of transient water table development. This work has identified components of the 3-D sub-surface, such as bedrock topography, that contribute to changing connectivity in saturated zones and the generation of sub-surface stormflow. Here, we test the ability of a 3-D hillslope model (both calibrated and uncalibrated) to simulate forested hillslope rainfall-runoff response and internal transient sub-surface stormflow dynamics. We also provide a transparent illustration of physics-based model development, issues of parameterization, examples of model rejection and usefulness of data types (e.g. runoff, mean soil moisture and transient water table depth) to the model enterprise. Our simulations show the inability of an uncalibrated model based on laboratory and field characterization of soil properties and topography to successfully simulate the integrated hydrological response or the distributed water table within the soil profile. Although not an uncommon result, the failure of the field-based characterized model to represent system behaviour is an important challenge that continues to vex scientists at many scales. We focus our attention particularly on examining the influence of bedrock permeability, soil anisotropy and drainable porosity on the development of patterns of transient groundwater and sub-surface flow. Internal dynamics of transient water table development prove to be essential in determining appropriate model parameterization. ?? 2010 John Wiley & Sons, Ltd.
NASA Technical Reports Server (NTRS)
Chow, S. H.
1974-01-01
The possible response of the atmosphere, as simulated by the two level Mintz-Arakawa global general circulation model, to a transient North Pacific sea surface temperature anomaly is investigated in terms of the energetics both in the spatial and wave number domains. Results indicate that the transient SST variations of reasonable magnitude in the North Pacific Ocean can induce a disturbing effect on the global energetics both in the spatial and wave number domains. The ability of the two level Mintz-Arakawa model to simulate the atmospheric energetics is also examined. Except in the tropics, the model exhibits a reasonable and realistic energy budget.
NASA Astrophysics Data System (ADS)
Jiang, L.; Shi, Z.; Xia, J.; Liang, J.; Lu, X.; Wang, Y.; Luo, Y.
2017-12-01
Uptake of anthropogenically emitted carbon (C) dioxide by terrestrial ecosystem is critical for determining future climate. However, Earth system models project large uncertainties in future C storage. To help identify sources of uncertainties in model predictions, this study develops a transient traceability framework to trace components of C storage dynamics. Transient C storage (X) can be decomposed into two components, C storage capacity (Xc) and C storage potential (Xp). Xc is the maximum C amount that an ecosystem can potentially store and Xp represents the internal capacity of an ecosystem to equilibrate C input and output for a network of pools. Xc is co-determined by net primary production (NPP) and residence time (𝜏N), with the latter being determined by allocation coefficients, transfer coefficients, environmental scalar, and exit rate. Xp is the product of redistribution matrix (𝜏ch) and net ecosystem exchange. We applied this framework to two contrasting ecosystems, Duke Forest and Harvard Forest with an ecosystem model. This framework helps identify the mechanisms underlying the responses of carbon cycling in the two forests to climate change. The temporal trajectories of X are similar between the two ecosystems. Using this framework, we found that two different mechanisms leading to the similar trajectory. This framework has potential to reveal mechanisms behind transient C storage in response to various global change factors. It can also identify sources of uncertainties in predicted transient C storage across models and can therefore be useful for model intercomparison.
Nonlinear rotordynamics analysis. [Space Shuttle Main Engine turbopumps
NASA Technical Reports Server (NTRS)
Noah, Sherif T.
1991-01-01
Effective analysis tools were developed for predicting the nonlinear rotordynamic behavior of the Space Shuttle Main Engine (SSME) turbopumps under steady and transient operating conditions. Using these methods, preliminary parametric studies were conducted on both generic and actual HPOTP (high pressure oxygen turbopump) models. In particular, a novel modified harmonic balance/alternating Fourier transform (HB/AFT) method was developed and used to conduct a preliminary study of the effects of fluid, bearing and seal forces on the unbalanced response of a multi-disk rotor in the presence of bearing clearances. The method makes it possible to determine periodic, sub-, super-synchronous and chaotic responses of a rotor system. The method also yields information about the stability of the obtained response, thus allowing bifurcation analyses. This provides a more effective capability for predicting the response under transient conditions by searching in proximity of resonance peaks. Preliminary results were also obtained for the nonlinear transient response of an actual HPOTP model using an efficient, newly developed numerical method based on convolution integration. Currently, the HB/AFT is being extended for determining the aperiodic response of nonlinear systems. Initial results show the method to be promising.
Nonthermal model for ultrafast laser-induced plasma generation around a plasmonic nanorod
NASA Astrophysics Data System (ADS)
Labouret, Timothée; Palpant, Bruno
2016-12-01
The excitation of plasmonic gold nanoparticles by ultrashort laser pulses can trigger interesting electron-based effects in biological media such as production of reactive oxygen species or cell membrane optoporation. In order to better understand the optical and thermal processes at play, we modeled the interaction of a subpicosecond, near-infrared laser pulse with a gold nanorod in water. A nonthermal model is used and compared to a simple two-temperature thermal approach. For both models, the computation of the transient optical response reveals strong plasmon damping. Electron emission from the metal into the water is also calculated in a specific way for each model. The dynamics of the resulting local plasma in water is assessed by a rate equation model. While both approaches provide similar results for the transient optical properties, the simple thermal one is unable to properly describe electron emission and plasma generation. The latter is shown to mostly originate from electron-electron thermionic emission and photoemission from the metal. Taking into account the transient optical response is mandatory to properly calculate both electron emission and local plasma dynamics in water.
A Nonlinear Model for Transient Responses from Light-Adapted Wolf Spider Eyes
DeVoe, Robert D.
1967-01-01
A quantitative model is proposed to test the hypothesis that the dynamics of nonlinearities in retinal action potentials from light-adapted wolf spider eyes may be due to delayed asymmetries in responses of the visual cells. For purposes of calculation, these delayed asymmetries are generated in an analogue by a time-variant resistance. It is first shown that for small incremental stimuli, the linear behavior of such a resistance describes peaking and low frequency phase lead in frequency responses of the eye to sinusoidal modulations of background illumination. It also describes the overshoots in linear step responses. It is next shown that the analogue accounts for nonlinear transient and short term DC responses to large positive and negative step stimuli and for the variations in these responses with changes in degree of light adaptation. Finally, a physiological model is proposed in which the delayed asymmetries in response are attributed to delayed rectification by the visual cell membrane. In this model, cascaded chemical reactions may serve to transduce visual stimuli into membrane resistance changes. PMID:6056011
Modeling fluvial incision and transient landscape evolution: Influence of dynamic channel adjustment
NASA Astrophysics Data System (ADS)
Attal, M.; Tucker, G. E.; Whittaker, A. C.; Cowie, P. A.; Roberts, G. P.
2008-09-01
Channel geometry exerts a fundamental control on fluvial processes. Recent work has shown that bedrock channel width depends on a number of parameters, including channel slope, and is not solely a function of drainage area as is commonly assumed. The present work represents the first attempt to investigate the consequences of dynamic, gradient-sensitive channel adjustment for drainage-basin evolution. We use the Channel-Hillslope Integrated Landscape Development (CHILD) model to analyze the response of a catchment to a given tectonic perturbation, using, as a template, the topography of a well-documented catchment in the footwall of an active normal fault in the Apennines (Italy) that is known to be undergoing a transient response to tectonic forcing. We show that the observed transient response can be reproduced to first order with a simple detachment-limited fluvial incision law. Transient landscape is characterized by gentler gradients and a shorter response time when dynamic channel adjustment is allowed. The differences in predicted channel geometry between the static case (width dependent solely on upstream area) and dynamic case (width dependent on both drainage area and channel slope) lead to contrasting landscape morphologies when integrated at the scale of a whole catchment, particularly in presence of strong tilting and/or pronounced slip-rate acceleration. Our results emphasize the importance of channel width in controlling fluvial processes and landscape evolution. They stress the need for using a dynamic hydraulic scaling law when modeling landscape evolution, particularly when the relative uplift field is nonuniform.
Transient thermal modeling of the nonscanning ERBE detector
NASA Technical Reports Server (NTRS)
Mahan, J. R.
1983-01-01
A numerical model to predict the transient thermal response of the ERBE nonscanning wide field of view total radiometer channel was developed. The model, which uses Monte Carlo techniques to characterize the radiative component of heat transfer, is described and a listing of the computer program is provided. Application of the model to simulate the actual blackbody calibration procedure is discussed. The use of the model to establish a real time flight data interpretation strategy is recommended. Modification of the model to include a simulated Earth radiation source field and a filter dome is indicated.
Multiple Systems of Spatial Memory: Evidence from Described Scenes
ERIC Educational Resources Information Center
Avraamides, Marios N.; Kelly, Jonathan W.
2010-01-01
Recent models in spatial cognition posit that distinct memory systems are responsible for maintaining transient and enduring spatial relations. The authors used perspective-taking performance to assess the presence of these enduring and transient spatial memories for locations encoded through verbal descriptions. Across 3 experiments, spatial…
CIRCUS--A digital computer program for transient analysis of electronic circuits
NASA Technical Reports Server (NTRS)
Moore, W. T.; Steinbert, L. L.
1968-01-01
Computer program simulates the time domain response of an electronic circuit to an arbitrary forcing function. CIRCUS uses a charge-control parameter model to represent each semiconductor device. Given the primary photocurrent, the transient behavior of a circuit in a radiation environment is determined.
Kinematic Model of Transient Shape-Induced Anisotropy in Dense Granular Flow
NASA Astrophysics Data System (ADS)
Nadler, B.; Guillard, F.; Einav, I.
2018-05-01
Nonspherical particles are ubiquitous in nature and industry, yet previous theoretical models of granular media are mostly limited to systems of spherical particles. The problem is that in systems of nonspherical anisotropic particles, dynamic particle alignment critically affects their mechanical response. To study the tendency of such particles to align, we propose a simple kinematic model that relates the flow to the evolution of particle alignment with respect to each other. The validity of the proposed model is supported by comparison with particle-based simulations for various particle shapes ranging from elongated rice-like (prolate) to flattened lentil-like (oblate) particles. The model shows good agreement with the simulations for both steady-state and transient responses, and advances the development of comprehensive constitutive models for shape-anisotropic particles.
Thermoviscoplastic response of thin plates subjected to intense local heating
NASA Technical Reports Server (NTRS)
Byrom, Ted G.; Allen, David H.; Thornton, Earl A.
1992-01-01
A finite element method is employed to investigate the thermoviscoplastic response of a half-cylinder to intense localized transient heating. Thermoviscoplastic material behavior is characterized by the Bodner-Partom constitutive model. Structure geometry is modeled with a three-dimensional assembly of CST-DKT plate elements incorporating the large deflection von Karman assumptions. The paper compares the results of a dynamic analysis with a quasi-static analysis for the half-cylinder structure with a step-function transient temperature loading similar to that which may be encountered with shock wave interference on a hypersonic leading edge.
Environmentally-induced discharge transient coupling to spacecraft
NASA Technical Reports Server (NTRS)
Viswanathan, R.; Barbay, G.; Stevens, N. J.
1985-01-01
The Hughes SCREENS (Space Craft Response to Environments of Space) technique was applied to generic spin and 3-axis stabilized spacecraft models. It involved the NASCAP modeling for surface charging and lumped element modeling for transients coupling into a spacecraft. A differential voltage between antenna and spun shelf of approx. 400 V and current of 12 A resulted from discharge at antenna for the spinner and approx. 3 kv and 0.3 A from a discharge at solar panels for the 3-axis stabilized Spacecraft. A typical interface circuit response was analyzed to show that the transients would couple into the Spacecraft System through ground points, which are most vulnerable. A compilation and review was performed on 15 years of available data from electron and ion current collection phenomena. Empirical models were developed to match data and compared with flight data of Pix-1 and Pix-2 mission. It was found that large space power systems would float negative and discharge if operated at or above 300 V. Several recommendations are given to improve the models and to apply them to large space systems.
NASA Astrophysics Data System (ADS)
Steinacher, M.; Joos, F.
2016-02-01
Information on the relationship between cumulative fossil CO2 emissions and multiple climate targets is essential to design emission mitigation and climate adaptation strategies. In this study, the transient response of a climate or environmental variable per trillion tonnes of CO2 emissions, termed TRE, is quantified for a set of impact-relevant climate variables and from a large set of multi-forcing scenarios extended to year 2300 towards stabilization. An ˜ 1000-member ensemble of the Bern3D-LPJ carbon-climate model is applied and model outcomes are constrained by 26 physical and biogeochemical observational data sets in a Bayesian, Monte Carlo-type framework. Uncertainties in TRE estimates include both scenario uncertainty and model response uncertainty. Cumulative fossil emissions of 1000 Gt C result in a global mean surface air temperature change of 1.9 °C (68 % confidence interval (c.i.): 1.3 to 2.7 °C), a decrease in surface ocean pH of 0.19 (0.18 to 0.22), and a steric sea level rise of 20 cm (13 to 27 cm until 2300). Linearity between cumulative emissions and transient response is high for pH and reasonably high for surface air and sea surface temperatures, but less pronounced for changes in Atlantic meridional overturning, Southern Ocean and tropical surface water saturation with respect to biogenic structures of calcium carbonate, and carbon stocks in soils. The constrained model ensemble is also applied to determine the response to a pulse-like emission and in idealized CO2-only simulations. The transient climate response is constrained, primarily by long-term ocean heat observations, to 1.7 °C (68 % c.i.: 1.3 to 2.2 °C) and the equilibrium climate sensitivity to 2.9 °C (2.0 to 4.2 °C). This is consistent with results by CMIP5 models but inconsistent with recent studies that relied on short-term air temperature data affected by natural climate variability.
Rheological effects on friction in elastohydrodynamic lubrication
NASA Technical Reports Server (NTRS)
Trachman, E. G.; Cheng, H. S.
1973-01-01
An analytical and experimental investigation is presented of the friction in a rolling and sliding elastohydrodynamic lubricated contact. The rheological behavior of the lubricant is described in terms of two viscoelastic models. These models represent the separate effects of non-Newtonian behavior and the transient response of the fluid. A unified description of the non-Newtonian shear rate dependence of the viscosity is presented as a new hyperbolic liquid model. The transient response of viscosity, following the rapid pressure rise encountered in the contact, is described by a compressional viscoelastic model of the volume response of a liquid to an applied pressure step. The resulting momentum and energy equations are solved by an iterative numerical technique, and a friction coefficient is calculated. The experimental study was performed, with two synthetic paraffinic lubricants, to verify the friction predictions of the analysis. The values of friction coefficient from theory and experiment are in close agreement.
VO2 Off Transient Kinetics in Extreme Intensity Swimming.
Sousa, Ana; Figueiredo, Pedro; Keskinen, Kari L; Rodríguez, Ferran A; Machado, Leandro; Vilas-Boas, João P; Fernandes, Ricardo J
2011-01-01
Inconsistencies about dynamic asymmetry between the on- and off- transient responses in oxygen uptake are found in the literature. Therefore, the purpose of this study was to characterize the oxygen uptake off-transient kinetics during a maximal 200-m front crawl effort, as examining the degree to which the on/off regularity of the oxygen uptake kinetics response was preserved. Eight high level male swimmers performed a 200-m front crawl at maximal speed during which oxygen uptake was directly measured through breath-by-breath oxymetry (averaged every 5 s). This apparatus was connected to the swimmer by a low hydrodynamic resistance respiratory snorkel and valve system. The on- and off-transient phases were symmetrical in shape (mirror image) once they were adequately fitted by a single-exponential regression models, and no slow component for the oxygen uptake response was developed. Mean (± SD) peak oxygen uptake was 69.0 (± 6.3) mL·kg(-1)·min(-1), significantly correlated with time constant of the off- transient period (r = 0.76, p < 0.05) but not with any of the other oxygen off-transient kinetic parameters studied. A direct relationship between time constant of the off-transient period and mean swimming speed of the 200-m (r = 0.77, p < 0.05), and with the amplitude of the fast component of the effort period (r = 0.72, p < 0.05) were observed. The mean amplitude and time constant of the off-transient period values were significantly greater than the respective on- transient. In conclusion, although an asymmetry between the on- and off kinetic parameters was verified, both the 200-m effort and the respectively recovery period were better characterized by a single exponential regression model. Key pointsThe VO2 slow component was not observed in the recovery period of swimming extreme efforts;The on and off transient periods were better fitted by a single exponential function, and so, these effort and recovery periods of swimming extreme efforts are symmetrical;The rate of VO2 decline during the recovery period may be due to not only the magnitude of oxygen debt but also the VO2peak obtained during the effort period.
NASA Technical Reports Server (NTRS)
Kana, D. D.; Vargas, L. M.
1977-01-01
Transient excitation forces were applied separately to simple beam-and-mass launch vehicle and payload models to develop complex admittance functions for the interface and other appropriate points on the structures. These measured admittances were then analytically combined by a matrix representation to obtain a description of the coupled system dynamic characteristics. Response of the payload model to excitation of the launch vehicle model was predicted and compared with results measured on the combined models. These results are also compared with results of earlier work in which a similar procedure was employed except that steady-state sinusoidal excitation techniques were included. It is found that the method employing transient tests produces results that are better overall than the steady state methods. Furthermore, the transient method requires far less time to implement, and provides far better resolution in the data. However, the data acquisition and handling problem is more complex for this method. It is concluded that the transient test and admittance matrix prediction method can be a valuable tool for development of payload vibration tests.
Effect of clothing material on thermal responses of the human body
NASA Astrophysics Data System (ADS)
Fengzhi, Li; Yi, Li
2005-09-01
The influence of clothing material on thermal responses of the human body are investigated by using an integrated model of a clothed thermoregulatory human body. A modified 25-nodes model considering the sweat accumulation on the skin surface is applied to simulate the human physiological regulatory responses. The heat and moisture coupled transfer mechanisms, including water vapour diffusion, the moisture evaporation/condensation, the moisture sorbtion/desorption by fibres, liquid sweat transfer under capillary pressure, and latent heat absorption/release due to phase change, are considered in the clothing model. On comparing prediction results with the experimental data in the literature, the proposed model seems able to predict dynamic heat and moisture transfer between the human body and the clothing system. The human body's thermal responses and clothing temperature and moisture variations are compared for different clothing materials during transient periods. We concluded that the hygroscopicity of clothing materials influences the human thermoregulation process significantly during environmental transients.
Transient hot-film sensor response in a shock tube
NASA Technical Reports Server (NTRS)
Roberts, A. S., Jr.; Ortgies, K. R.; Gartenberg, E.
1989-01-01
Shock tube experiments were performed to determine the response of a hot-film sensor, mounted flush on the side wall of a shock tube, to unsteady flow behind a normal shock wave. The present experiments attempt to isolate the response of the anemometer due only to the change in convective heat transfer at the hot-film surface. The experiments, performed at low supersonic shock speeds in air, are described along with the data acquisition procedure. The change in convective heat transfer is deduced from the data and the results are compared with those from transient boundary layer theory and another set of experimental results. Finally, a transient local heat transfer coefficient is formulated for use as the forcing function in a hot-film sensor instrument model simulation.
Data-driven Modeling of Metal-oxide Sensors with Dynamic Bayesian Networks
NASA Astrophysics Data System (ADS)
Gosangi, Rakesh; Gutierrez-Osuna, Ricardo
2011-09-01
We present a data-driven probabilistic framework to model the transient response of MOX sensors modulated with a sequence of voltage steps. Analytical models of MOX sensors are usually built based on the physico-chemical properties of the sensing materials. Although building these models provides an insight into the sensor behavior, they also require a thorough understanding of the underlying operating principles. Here we propose a data-driven approach to characterize the dynamical relationship between sensor inputs and outputs. Namely, we use dynamic Bayesian networks (DBNs), probabilistic models that represent temporal relations between a set of random variables. We identify a set of control variables that influence the sensor responses, create a graphical representation that captures the causal relations between these variables, and finally train the model with experimental data. We validated the approach on experimental data in terms of predictive accuracy and classification performance. Our results show that DBNs can accurately predict the dynamic response of MOX sensors, as well as capture the discriminatory information present in the sensor transients.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Miller, Nicholas W.; Shao, Miaolei; Pajic, Slobodan
The addition of large amounts of wind and solar generation to bulk power systems that are traditionally subject to operating constraints set by transient stability and frequency response limitations is the subject of considerable concern in the industry. The US Western Interconnection (WI) is expected to experience substantial additional growth in both wind and solar generation. These plants will, to some extent, displace large central station thermal generation, both coal and gas-fired, which have traditionally helped maintain stability. This paper reports the results of a study that investigated the transient stability and frequency response of the WI with high penetrationsmore » of wind and solar generation. The main goals of this work were to (1) create a realistic, baseline model of the WI, (2) test selected transient stability and frequency events, (3) investigate the impact of large amounts of wind and solar generation, and (4) examine means to improve performance.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Clark, Kara; Miller, Nicholas W.; Shao, Miaolei
Adding large amounts of wind and solar generation to bulk power systems that are traditionally subject to operating constraints set by transient stability and frequency response limitations is the subject of considerable concern in the industry. The US Western Interconnection (WI) is expected to experience substantial additional growth in both wind and solar generation. These plants will, to some extent, displace large central station thermal generation, both coal and gas-fired, which have traditionally helped maintain stability. Our paper reports the results of a study that investigated the transient stability and frequency response of the WI with high penetrations of windmore » and solar generation. Moreover, the main goals of this work were to (1) create a realistic, baseline model of the WI, (2) test selected transient stability and frequency events, (3) investigate the impact of large amounts of wind and solar generation, and (4) examine means to improve performance.« less
Convective response of a wall-mounted hot-film sensor in a shock tube
NASA Technical Reports Server (NTRS)
Roberts, A. Sidney, Jr.; Ortgies, Kelly R.; Gartenberg, Ehud; Carraway, Debra L.
1991-01-01
Shock tube experiments were performed in order to determine the response of a single hot-film element of a sensor array to transiently induced flow behind weak normal shock waves. The experiments attempt to isolate the response due only to the change in convective heat transfer at the hot-film surface mounted on the wall of the shock tube. The experiments are described, the results being correlated with transient boundary layer theory and compared with an independent set of experimental results. One of the findings indicates that the change in the air properties (temperature and pressure) precedes the air mass transport, causing an ambiguity in the sensor response to the development of the velocity boundary layer. Also, a transient, local heat transfer coefficient is formulated to be used as a forcing function in an hot-film instrument model and simulation which remains under investigation.
Transient Catalytic Combustor Model With Detailed Gas and Surface Chemistry
NASA Technical Reports Server (NTRS)
Struk, Peter M.; Dietrich, Daniel L.; Mellish, Benjamin P.; Miller, Fletcher J.; Tien, James S.
2005-01-01
In this work, we numerically investigate the transient combustion of a premixed gas mixture in a narrow, perfectly-insulated, catalytic channel which can represent an interior channel of a catalytic monolith. The model assumes a quasi-steady gas-phase and a transient, thermally thin solid phase. The gas phase is one-dimensional, but it does account for heat and mass transfer in a direction perpendicular to the flow via appropriate heat and mass transfer coefficients. The model neglects axial conduction in both the gas and in the solid. The model includes both detailed gas-phase reactions and catalytic surface reactions. The reactants modeled so far include lean mixtures of dry CO and CO/H2 mixtures, with pure oxygen as the oxidizer. The results include transient computations of light-off and system response to inlet condition variations. In some cases, the model predicts two different steady-state solutions depending on whether the channel is initially hot or cold. Additionally, the model suggests that the catalytic ignition of CO/O2 mixtures is extremely sensitive to small variations of inlet equivalence ratios and parts per million levels of H2.
Design and model for the giant magnetostrictive actuator used on an electronic controlled injector
NASA Astrophysics Data System (ADS)
Xue, Guangming; Zhang, Peilin; He, Zhongbo; Li, Ben; Rong, Ce
2017-05-01
Giant magnetostrictive actuator (GMA) may be a promising candidate actuator to drive an electronic controlled injector as giant magnetostrictive material (GMM) has excellent performances as large output, fast response and high operating stability etc. To meet the driving requirement of the injector, the GMA should produce maximal shortening displacement when energized. An unbiased GMA with a ‘T’ shaped output rod is designed to reach the target. Furthermore, an open-hold-fall type driving voltage is exerted on the actuator coil to accelerate the response speed of the coil current. The actuator displacement is modeled from establishing the sub-models of coil current, magnetic field within GMM rod, magnetization and magnetostrictive strain sequentially. Two modifications are done to make the model more accurate. Firstly, consider the model fails to compute the transient-state response precisely, a dead-zone and delay links are embedded into the coil current sub-model. Secondly, as the magnetization and magnetostrictive strain sub-models just influence the change rule of the transient-state response the linear magnetostrictive strain-magnetic field sub-model is introduced. From experimental results, the modified model with linear magnetostrictive stain expression can predict the actuator displacement quite effectively.
A Model of Solid State Gas Sensors
NASA Astrophysics Data System (ADS)
Woestman, J. T.; Brailsford, A. D.; Shane, M.; Logothetis, E. M.
1997-03-01
Solid state gas sensors are widely used to measure the concentrations of gases such as CO, CH_4, C_3H_6, H_2, C_3H8 and O2 The applications of these sensors range from air-to-fuel ratio control in combustion processes including those in automotive engines and industrial furnaces to leakage detection of inflammable and toxic gases in domestic and industrial environments. As the need increases to accurately measure smaller and smaller concentrations, problems such as poor selectivity, stability and response time limit the use of these sensors. In an effort to overcome some of these limitations, a theoretical model of the transient behavior of solid state gas sensors has been developed. In this presentation, a model for the transient response of an electrochemical gas sensor to gas mixtures containing O2 and one reducing species, such as CO, is discussed. This model accounts for the transport of the reactive species to the sampling electrode, the catalyzed oxidation/reduction reaction of these species and the generation of the resulting electrical signal. The model will be shown to reproduce the results of published steady state models and to agree with experimental steady state and transient data.
NASA Astrophysics Data System (ADS)
Schurer, Andrew; Hegerl, Gabriele
2016-04-01
The evaluation of the transient climate response (TCR) is of critical importance to policy makers as it can be used to calculate a simple estimate of the expected warming given predicted greenhouse gas emissions. Previous studies using optimal detection techniques have been able to estimate a TCR value from the historic record using simulations from some of the models which took part in the Coupled Model Intercomparison Project Phase 5 (CMIP5) but have found that others give unconstrained results. At least partly this is due to degeneracy between the greenhouse gas and aerosol signals which makes separation of the temperature response to these forcings problematic. Here we re-visit this important topic by using an adapted optimal detection analysis within a Bayesian framework. We account for observational uncertainty by the use of an ensemble of instrumental observations, and model uncertainty by combining the results from several different models. This framework allows the use of prior information which is found to help separate the response to the different forcings leading to a more constrained estimate of TCR.
Perception of differences in naturalistic dynamic scenes, and a V1-based model.
To, Michelle P S; Gilchrist, Iain D; Tolhurst, David J
2015-01-16
We investigate whether a computational model of V1 can predict how observers rate perceptual differences between paired movie clips of natural scenes. Observers viewed 198 pairs of movies clips, rating how different the two clips appeared to them on a magnitude scale. Sixty-six of the movie pairs were naturalistic and those remaining were low-pass or high-pass spatially filtered versions of those originals. We examined three ways of comparing a movie pair. The Spatial Model compared corresponding frames between each movie pairwise, combining those differences using Minkowski summation. The Temporal Model compared successive frames within each movie, summed those differences for each movie, and then compared the overall differences between the paired movies. The Ordered-Temporal Model combined elements from both models, and yielded the single strongest predictions of observers' ratings. We modeled naturalistic sustained and transient impulse functions and compared frames directly with no temporal filtering. Overall, modeling naturalistic temporal filtering improved the models' performance; in particular, the predictions of the ratings for low-pass spatially filtered movies were much improved by employing a transient impulse function. The correlations between model predictions and observers' ratings rose from 0.507 without temporal filtering to 0.759 (p = 0.01%) when realistic impulses were included. The sustained impulse function and the Spatial Model carried more weight in ratings for normal and high-pass movies, whereas the transient impulse function with the Ordered-Temporal Model was most important for spatially low-pass movies. This is consistent with models in which high spatial frequency channels with sustained responses primarily code for spatial details in movies, while low spatial frequency channels with transient responses code for dynamic events. © 2015 ARVO.
Investigation of models for large-scale meteorological prediction experiments
NASA Technical Reports Server (NTRS)
Spar, J.
1973-01-01
Studies are reported of the long term responses of the model atmosphere to anomalies in snow cover and sea surface temperature. An abstract of a previously issued report on the computed response to surface anomalies in a global atmospheric model is presented, and the experiments on the effects of transient sea surface temperature on the Mintz-Arakawa atmospheric model are reported.
NASA Astrophysics Data System (ADS)
Leach, J.; Moore, D.
2015-12-01
Winter stream temperature of coastal mountain catchments influences fish growth and development. Transient snow cover and advection associated with lateral throughflow inputs are dominant controls on stream thermal regimes in these regions. Existing stream temperature models lack the ability to properly simulate these processes. Therefore, we developed and evaluated a conceptual-parametric catchment-scale stream temperature model that includes the role of transient snow cover and lateral advection associated with throughflow. The model provided reasonable estimates of observed stream temperature at three test catchments. We used the model to simulate winter stream temperature for virtual catchments located at different elevations within the rain-on-snow zone. The modelling exercise examined stream temperature response associated with interactions between elevation, snow regime, and changes in air temperature. Modelling results highlight that the sensitivity of winter stream temperature response to changes in climate may be dependent on catchment elevation and landscape position.
NASA Astrophysics Data System (ADS)
Takahashi, Toshimichi
2018-05-01
The tyre model which formerly developed by the author et al. and describes the tyre transient responses of side force and aligning moment under the time-varying vertical force was implemented to the vehicle dynamics simulation software and the influence of tyre side force transient property on the vehicle behaviour was investigated. The vehicle responses with/without tyre transient property on sinusoidally undulated road surfaces were simulated and compared. It was found that the average lateral acceleration of the vehicle at the sinusoidal steering wheel angle input decreases on the undulated road of long wavelength (3 m) for both cases, but when the wavelength becomes shorter (1 m), the average lateral acceleration increases only in the case that the transient property is considered. The cause of those changes is explained by using the tyre-related variables. Also the steady-state turning behaviour of the vehicle on undulated roads are shown and discussed.
Data Assimilation with the Extended Cmam: Nudging to Re-Analyses of the Lower Atmosphere
NASA Astrophysics Data System (ADS)
Fomichev, V. I.; Beagley, S. R.; Shepherd, M. G.; Semeniuk, K.; Mclandress, C. W.; Scinocca, J.; McConnell, J. C.
2012-12-01
The extended CMAM is currently being run in a forecast mode allowing the use of the model to simulate specific events. The current analysis period covers 1990-2010. The model is forced using ERA-Interim re-analyses via a nudging technique for the troposphere/stratosphere in combination with the GCM evolution in the lower atmosphere. Thus a transient forced model state is created in the lower atmosphere. The upper atmosphere is allowed to evolve in response to the observed conditions occurring in the lower atmosphere and in response to other transient forcing's such as SSTs, solar flux, and CO2 and CFC boundary changes. This methodology allows specific events and observations to be more successfully compared with the model. The model results compared to TOMS and ACE observations show a good agreement.
Computational modeling of cardiovascular response to orthostatic stress
NASA Technical Reports Server (NTRS)
Heldt, Thomas; Shim, Eun B.; Kamm, Roger D.; Mark, Roger G.
2002-01-01
The objective of this study is to develop a model of the cardiovascular system capable of simulating the short-term (< or = 5 min) transient and steady-state hemodynamic responses to head-up tilt and lower body negative pressure. The model consists of a closed-loop lumped-parameter representation of the circulation connected to set-point models of the arterial and cardiopulmonary baroreflexes. Model parameters are largely based on literature values. Model verification was performed by comparing the simulation output under baseline conditions and at different levels of orthostatic stress to sets of population-averaged hemodynamic data reported in the literature. On the basis of experimental evidence, we adjusted some model parameters to simulate experimental data. Orthostatic stress simulations are not statistically different from experimental data (two-sided test of significance with Bonferroni adjustment for multiple comparisons). Transient response characteristics of heart rate to tilt also compare well with reported data. A case study is presented on how the model is intended to be used in the future to investigate the effects of post-spaceflight orthostatic intolerance.
Li, Xiaogai; von Holst, Hans; Kleiven, Svein
2013-01-01
A 3D finite element (FE) model has been developed to study the mean intracranial pressure (ICP) response during constant-rate infusion using linear poroelasticity. Due to the uncertainties in the poroelastic constants for brain tissue, the influence of each of the main parameters on the transient ICP infusion curve was studied. As a prerequisite for transient analysis, steady-state simulations were performed first. The simulated steady-state pressure distribution in the brain tissue for a normal cerebrospinal fluid (CSF) circulation system showed good correlation with experiments from the literature. Furthermore, steady-state ICP closely followed the infusion experiments at different infusion rates. The verified steady-state models then served as a baseline for the subsequent transient models. For transient analysis, the simulated ICP shows a similar tendency to that found in the experiments, however, different values of the poroelastic constants have a significant effect on the infusion curve. The influence of the main poroelastic parameters including the Biot coefficient α, Skempton coefficient B, drained Young's modulus E, Poisson's ratio ν, permeability κ, CSF absorption conductance C(b) and external venous pressure p(b) was studied to investigate the influence on the pressure response. It was found that the value of the specific storage term S(ε) is the dominant factor that influences the infusion curve, and the drained Young's modulus E was identified as the dominant parameter second to S(ε). Based on the simulated infusion curves from the FE model, artificial neural network (ANN) was used to find an optimised parameter set that best fit the experimental curve. The infusion curves from both the FE simulation and using ANN confirmed the limitation of linear poroelasticity in modelling the transient constant-rate infusion.
Transient combustion in hybrid rockets
NASA Astrophysics Data System (ADS)
Karabeyoglu, Mustafa Arif
1998-09-01
Hybrid rockets regained interest recently as an alternative chemical propulsion system due to their advantages over the solid and liquid systems that are currently in use. Development efforts on hybrids revealed two important problem areas: (1) low frequency instabilities and (2) slow transient response. Both of these are closely related to the transient behavior which is a poorly understood aspect of hybrid operation. This thesis is mainly involved with a theoretical study of transient combustion in hybrid rockets. We follow the methodology of identifying and modeling the subsystems of the motor such as the thermal lags in the solid, boundary layer combustion and chamber gasdynamics from a dynamic point of view. We begin with the thermal lag in the solid which yield the regression rate for any given wall heat flux variation. Interesting phenomena such as overshooting during throttling and the amplification and phase lead regions in the frequency domain are discovered. Later we develop a quasi-steady transient hybrid combustion model supported with time delays for the boundary layer processes. This is integrated with the thermal lag system to obtain the thermal combustion (TC) coupled response. The TC coupled system with positive delays generated low frequency instabilities. The scaling of the instabilities are in good agreement with actual motor test data. Finally, we formulate a gasdynamic model for the hybrid chamber which successfully resolves the filling/emptying and longitudinal acoustic behavior of the motor. The TC coupled system is later integrated to the gasdynamic model to obtain the overall response (TCG coupled system) of gaseous oxidizer motors with stiff feed systems. Low frequency instabilities were also encountered for the TCG coupled system. Apart from the transient investigations, the regression rate behavior of liquefying hybrid propellants such as solid cryogenic materials are also studied. The theory is based on the possibility of enhancement of regression rate by the entrainment mass transfer from a liquid layer formed on the fuel surface. The predicted regression rates are in good agreement with the cryogenic experimental findings obtained recently at Edwards Airforce Base with a frozen pentane and gaseous oxygen system.
NASA Astrophysics Data System (ADS)
Qi, Youzheng; Huang, Ling; Wu, Xin; Zhu, Wanhua; Fang, Guangyou; Yu, Gang
2017-07-01
Quantitative modeling of the transient electromagnetic (TEM) response requires consideration of the full transmitter waveform, i.e., not only the specific current waveform in a half cycle but also the bipolar repetition. In this paper, we present a novel temporal interpolation and convolution (TIC) method to facilitate the accurate TEM modeling. We first calculate the temporal basis response on a logarithmic scale using the fast digital-filter-based methods. Then, we introduce a function named hamlogsinc in the framework of discrete signal processing theory to reconstruct the basis function and to make the convolution with the positive half of the waveform. Finally, a superposition procedure is used to take account of the effect of previous bipolar waveforms. Comparisons with the established fast Fourier transform method demonstrate that our TIC method can get the same accuracy with a shorter computing time.
Transient quantum coherent response to a partially coherent radiation field.
Sadeq, Zaheen S; Brumer, Paul
2014-02-21
The response of an arbitrary closed quantum system to a partially coherent electric field is investigated, with a focus on the transient coherences in the system. As a model we examine, both perturbatively and numerically, the coherences induced in a three level V system. Both rapid turn-on and pulsed turn-on effects are investigated. The effect of a long and incoherent pulse is also considered, demonstrating that during the pulse the system shows a coherent response which reduces after the pulse is over. Both the pulsed scenario and the thermally broadened CW case approach a mixed state in the long time limit, with rates dictated by the adjacent level spacings and the coherence time of the light, and via a mechanism that is distinctly different from traditional decoherence. These two excitation scenarios are also explored for a minimal "toy" model of the electronic levels in pigment protein complex PC645 by both a collisionally broadened CW laser and by a noisy pulse, where unexpectedly long transient coherence times are observed and explained. The significance of environmentally induced decoherence is noted.
Equivalent circuit simulation of HPEM-induced transient responses at nonlinear loads
NASA Astrophysics Data System (ADS)
Kotzev, Miroslav; Bi, Xiaotang; Kreitlow, Matthias; Gronwald, Frank
2017-09-01
In this paper the equivalent circuit modeling of a nonlinearly loaded loop antenna and its transient responses to HPEM field excitations are investigated. For the circuit modeling the general strategy to characterize the nonlinearly loaded antenna by a linear and a nonlinear circuit part is pursued. The linear circuit part can be determined by standard methods of antenna theory and numerical field computation. The modeling of the nonlinear circuit part requires realistic circuit models of the nonlinear loads that are given by Schottky diodes. Combining both parts, appropriate circuit models are obtained and analyzed by means of a standard SPICE circuit simulator. It is the main result that in this way full-wave simulation results can be reproduced. Furthermore it is clearly seen that the equivalent circuit modeling offers considerable advantages with respect to computation speed and also leads to improved physical insights regarding the coupling between HPEM field excitation and nonlinearly loaded loop antenna.
Performance Enhancement of the NPS Transient Electromagnetic Scattering Laboratory
1991-09-01
MASTER OF SCIENCE IN ELECTRICAL ENGINEERING MASTER OF SCIENCE IN SYSTEMS ENGINEERING (ELECTRONIC WARFARE) from NAVAL POSTGRADUATE S OOL Author: JvAlo...Bresani Approved by: Michael A. Morgan, Thesis Advisor Jeffrey B. Knorr, Second Reader Michael A. Morgan, Chairman, Department of Electrical & Computer...SYSTEM REPRESENTATION ... .......... 13 B. MATHEMATICAL MODEL ......... ..... 15 C. TRANSIENT RESPONSE EVALUATION .. ......... . 17 IV. MEASUREMENT
Modeling of the Multiparameter Inverse Task of Transient Thermography
NASA Technical Reports Server (NTRS)
Plotnikov, Y. A.
1998-01-01
Transient thermography employs preheated surface temperature variations caused by delaminations, cracks, voids, corroded regions, etc. Often, it is enough to detect these changes to declare a defect in a workpiece. It is also desirable to obtain additional information about the defect from the thermal response. The planar size, depth, and thermal resistance of the detected defects are the parameters of interest. In this paper a digital image processing technique is applied to simulated thermal responses in order to obtain the geometry of the inclusion-type defects in a flat panel. A three-dimensional finite difference model in Cartesian coordinates is used for the numerical simulations. Typical physical properties of polymer graphite composites are assumed. Using different informative parameters of the thermal response for depth estimation is discussed.
Calculation of transient potential rise on the wind turbine struck by lightning.
Xiaoqing, Zhang
2014-01-01
A circuit model is proposed in this paper for calculating the transient potential rise on the wind turbine struck by lightning. The model integrates the blade, sliding contact site, and tower and grounding system of the wind turbine into an equivalent circuit. The lightning current path from the attachment point to the ground can be fully described by the equivalent circuit. The transient potential responses are obtained in the different positions on the wind turbine by solving the circuit equations. In order to check the validity of the model, the laboratory measurement is made with a reduced-scale wind turbine. The measured potential waveform is compared with the calculated one and a better agreement is shown between them. The practical applicability of the model is also examined by a numerical example of a 2 MW Chinese-built wind turbine.
Electromagnetic Test-Facility characterization: an identification approach
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zicker, J.E.; Candy, J.V.
The response of an object subjected to high energy, transient electromagnetic (EM) fields sometimes called electromagnetic pulses (EMP), is an important issue in the survivability of electronic systems (e.g., aircraft), especially when the field has been generated by a high altitude nuclear burst. The characterization of transient response information is a matter of national concern. In this report we discuss techniques to: (1) improve signal processing at a test facility; and (2) parameterize a particular object response. First, we discuss the application of identification-based signal processing techniques to improve signal levels at the Lawrence Livermore National Laboratory (LLNL) EM Transientmore » Test Facility. We identify models of test equipment and then use these models to deconvolve the input/output sequences for the object under test. A parametric model of the object is identified from this data. The model can be used to extrapolate the response to these threat level EMP. Also discussed is the development of a facility simulator (EMSIM) useful for experimental design and calibration and a deconvolution algorithm (DECONV) useful for removing probe effects from the measured data.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cartas, Raul; Mimendia, Aitor; Valle, Manel del
2009-05-23
Calibration models for multi-analyte electronic tongues have been commonly built using a set of sensors, at least one per analyte under study. Complex signals recorded with these systems are formed by the sensors' responses to the analytes of interest plus interferents, from which a multivariate response model is then developed. This work describes a data treatment method for the simultaneous quantification of two species in solution employing the signal from a single sensor. The approach used here takes advantage of the complex information recorded with one electrode's transient after insertion of sample for building the calibration models for both analytes.more » The departure information from the electrode was firstly processed by discrete wavelet for transforming the signals to extract useful information and reduce its length, and then by artificial neural networks for fitting a model. Two different potentiometric sensors were used as study case for simultaneously corroborating the effectiveness of the approach.« less
NASA Technical Reports Server (NTRS)
Solomon, Sean C.; Frey, H. V. (Technical Monitor)
2002-01-01
This is the Final Technical Report on research conducted between 1 June 1997 and 14 September 2001 entitled "Transients in Pacific/North American plate boundary deformation: Synthesis and modeling of GPS and borehole strain observations." As the project title implies, our effort involved a geodetic study of strain transients, i.e., temporal variations in deformation rates, that occur within plate boundary zones and their relationship to earthquakes and plate motions. Important transients occur during and following large earthquakes, and there are also strain transients not apparently associated with earthquakes. A particularly intriguing class of transients, for which there is a modest but growing list of examples, are preseismic anomalies. Such earthquake precursors, if further documented and understood, would have obvious importance for earthquake hazard mitigation. Because the timescales for these diverse transients range over at least 6 orders of magnitude (minutes to years), no single geodetic technique is optimum. We therefore undertook a systematic synthesis of Global Positioning Satellite (GPS) and borehole strainmeter data in three areas in California where there are adequate numbers of both types of instruments (or their equivalent): the San Francisco Bay region (within the Bay Area Regional Deformation network), southern California (within the Southern California Integrated GPS Network), and Parkfield (where a two-color laser system provides a proxy for continuous GPS measurements). An integral component of our study was the elucidation of the physical mechanisms by which such transients occur and propagate. We therefore initiated the development of multiple forward models, using two independent approaches. In the first, we explored the response to specified earthquake slip in viscoelastic models that incorporated failure criteria and the geometry of major faults in California. In the second approach, we examined the dynamical response of a complex rheological medium to the application of a far-field stress imposed by plate motions. The forward models were used both to gain insight into the range of strain transients to be expected under different assumed mechanical conditions and to develop representations for strain fields that allow GPS, borehole, and other strain data to be combined in a self-consistent, yet well-determined, manner. The models also provided a basis for hypothesis testing, by which data from a strain transient well characterized by GPS and borehole observations were utilized to distinguish among competing candidates for the causative physical mechanism and the governing physical characteristics. During the three years of this project, continued to a fourth year through a no-cost extension of the grant, we published 14 papers and presented or co-authored 37 papers at national scientific meetings.
Capilla, Almudena; Pazo-Alvarez, Paula; Darriba, Alvaro; Campo, Pablo; Gross, Joachim
2011-01-01
Background One common criterion for classifying electrophysiological brain responses is based on the distinction between transient (i.e. event-related potentials, ERPs) and steady-state responses (SSRs). The generation of SSRs is usually attributed to the entrainment of a neural rhythm driven by the stimulus train. However, a more parsimonious account suggests that SSRs might result from the linear addition of the transient responses elicited by each stimulus. This study aimed to investigate this possibility. Methodology/Principal Findings We recorded brain potentials elicited by a checkerboard stimulus reversing at different rates. We modeled SSRs by sequentially shifting and linearly adding rate-specific ERPs. Our results show a strong resemblance between recorded and synthetic SSRs, supporting the superposition hypothesis. Furthermore, we did not find evidence of entrainment of a neural oscillation at the stimulation frequency. Conclusions/Significance This study provides evidence that visual SSRs can be explained as a superposition of transient ERPs. These findings have critical implications in our current understanding of brain oscillations. Contrary to the idea that neural networks can be tuned to a wide range of frequencies, our findings rather suggest that the oscillatory response of a given neural network is constrained within its natural frequency range. PMID:21267081
Modeling rate sensitivity of exercise transient responses to limb motion.
Yamashiro, Stanley M; Kato, Takahide
2014-10-01
Transient responses of ventilation (V̇e) to limb motion can exhibit predictive characteristics. In response to a change in limb motion, a rapid change in V̇e is commonly observed with characteristics different than during a change in workload. This rapid change has been attributed to a feed-forward or adaptive response. Rate sensitivity was explored as a specific hypothesis to explain predictive V̇e responses to limb motion. A simple model assuming an additive feed-forward summation of V̇e proportional to the rate of change of limb motion was studied. This model was able to successfully account for the adaptive phase correction observed during human sinusoidal changes in limb motion. Adaptation of rate sensitivity might also explain the reduction of the fast component of V̇e responses previously reported following sudden exercise termination. Adaptation of the fast component of V̇e response could occur by reduction of rate sensitivity. Rate sensitivity of limb motion was predicted by the model to reduce the phase delay between limb motion and V̇e response without changing the steady-state response to exercise load. In this way, V̇e can respond more quickly to an exercise change without interfering with overall feedback control. The asymmetry between responses to an incremental and decremental ramp change in exercise can also be accounted for by the proposed model. Rate sensitivity leads to predicted behavior, which resembles responses observed in exercise tied to expiratory reserve volume. Copyright © 2014 the American Physiological Society.
Near contact phenomena and transient effects in far infrared photoconductors
NASA Technical Reports Server (NTRS)
Haegel, Nancy M.
1989-01-01
A combination of experimental and modeling work is summarized in two areas: first, the calculation of excess free carrier and space charge distributions near contacts and their effects on device resistivity, and second, the characterization of a slow transient response (tau approx. 1 sec) in Ge:Be detectors which is due to trapping associated with Be(+) formation. In both cases, analytical models, based on continuity and rate equations, have been developed to enable the application of these findings to a wide variety of photoconductor materials.
NASA Astrophysics Data System (ADS)
Seo, H.; Kwon, Y. O.; Joyce, T. M.; Ummenhofer, C.
2016-12-01
This study examines the North Atlantic atmospheric circulation response to the meridional shift of Gulf Stream path using a large-ensemble, high-resolution, and hemispheric-scale WRF simulations. The model is forced with wintertime SST anomalies derived from a wide range of Gulf Stream shift scenarios. The key result of the model experiments, supported in part by an independent analysis of a reanalysis data set, is that the large-scale, quasi-steady North Atlantic circulation response is unambiguously nonlinear about the sign and amplitude of chosen SST anomalies. This nonlinear response prevails over the weak linear response and resembles the negative North Atlantic Oscillation, the leading intrinsic mode of variability in the model and the observations. Further analysis of the associated dynamics reveals that the nonlinear responses are accompanied by the anomalous southward shift of the North Atlantic eddy-driven jet stream, which is reinforced nearly equally by the high-frequency transient eddy feedback and the low-frequency high-latitude wave breaking events. The result highlights the importance of the intrinsically nonlinear transient eddy dynamics and eddy-mean flow interactions in generating the nonlinear forced response to the meridional shift in the Gulf Stream.
Transient modeling in simulation of hospital operations for emergency response.
Paul, Jomon Aliyas; George, Santhosh K; Yi, Pengfei; Lin, Li
2006-01-01
Rapid estimates of hospital capacity after an event that may cause a disaster can assist disaster-relief efforts. Due to the dynamics of hospitals, following such an event, it is necessary to accurately model the behavior of the system. A transient modeling approach using simulation and exponential functions is presented, along with its applications in an earthquake situation. The parameters of the exponential model are regressed using outputs from designed simulation experiments. The developed model is capable of representing transient, patient waiting times during a disaster. Most importantly, the modeling approach allows real-time capacity estimation of hospitals of various sizes and capabilities. Further, this research is an analysis of the effects of priority-based routing of patients within the hospital and the effects on patient waiting times determined using various patient mixes. The model guides the patients based on the severity of injuries and queues the patients requiring critical care depending on their remaining survivability time. The model also accounts the impact of prehospital transport time on patient waiting time.
A discourse on sensitivity analysis for discretely-modeled structures
NASA Technical Reports Server (NTRS)
Adelman, Howard M.; Haftka, Raphael T.
1991-01-01
A descriptive review is presented of the most recent methods for performing sensitivity analysis of the structural behavior of discretely-modeled systems. The methods are generally but not exclusively aimed at finite element modeled structures. Topics included are: selections of finite difference step sizes; special consideration for finite difference sensitivity of iteratively-solved response problems; first and second derivatives of static structural response; sensitivity of stresses; nonlinear static response sensitivity; eigenvalue and eigenvector sensitivities for both distinct and repeated eigenvalues; and sensitivity of transient response for both linear and nonlinear structural response.
Do Magnetic Fields Drive High-Energy Explosive Transients?
NASA Astrophysics Data System (ADS)
Mundell, Carole
2017-10-01
I will review the current state-of-the-art in real-time, rapid response optical imaging and polarimetric followup of transient sources such as Gamma Ray Bursts. I will interpret current results within the context of the external shock model and present predictions for future mm- and cm-wave radio observatories. Recent observational results from new radio pilot studies will also be presented.
Analysis and testing of a space crane articulating joint testbed
NASA Technical Reports Server (NTRS)
Sutter, Thomas R.; Wu, K. Chauncey
1992-01-01
The topics are presented in viewgraph form and include: space crane concept with mobile base; mechanical versus structural articulating joint; articulating joint test bed and reference truss; static and dynamic characterization completed for space crane reference truss configuration; improved linear actuators reduce articulating joint test bed backlash; 1-DOF space crane slew maneuver; boom 2 tip transient response finite element dynamic model; boom 2 tip transient response shear-corrected component modes torque driver profile; peak root member force vs. slew time torque driver profile; and open loop control of space crane motion.
Aubry-Hivet, D; Nziengui, H; Rapp, K; Oliveira, O; Paponov, I A; Li, Y; Hauslage, J; Vagt, N; Braun, M; Ditengou, F A; Dovzhenko, A; Palme, K
2014-01-01
Plant roots are among most intensively studied biological systems in gravity research. Altered gravity induces asymmetric cell growth leading to root bending. Differential distribution of the phytohormone auxin underlies root responses to gravity, being coordinated by auxin efflux transporters from the PIN family. The objective of this study was to compare early transcriptomic changes in roots of Arabidopsis thaliana wild type, and pin2 and pin3 mutants under parabolic flight conditions and to correlate these changes to auxin distribution. Parabolic flights allow comparison of transient 1-g, hypergravity and microgravity effects in living organisms in parallel. We found common and mutation-related genes differentially expressed in response to transient microgravity phases. Gene ontology analysis of common genes revealed lipid metabolism, response to stress factors and light categories as primarily involved in response to transient microgravity phases, suggesting that fundamental reorganisation of metabolic pathways functions upstream of a further signal mediating hormonal network. Gene expression changes in roots lacking the columella-located PIN3 were stronger than in those deprived of the epidermis and cortex cell-specific PIN2. Moreover, repetitive exposure to microgravity/hypergravity and gravity/hypergravity flight phases induced an up-regulation of auxin responsive genes in wild type and pin2 roots, but not in pin3 roots, suggesting a critical function of PIN3 in mediating auxin fluxes in response to transient microgravity phases. Our study provides important insights towards understanding signal transduction processes in transient microgravity conditions by combining for the first time the parabolic flight platform with the transcriptome analysis of different genetic mutants in the model plant, Arabidopsis. © 2013 German Botanical Society and The Royal Botanical Society of the Netherlands.
Aeroelastic Modeling of a Nozzle Startup Transient
NASA Technical Reports Server (NTRS)
Wang, Ten-See; Zhao, Xiang; Zhang, Sijun; Chen, Yen-Sen
2014-01-01
Lateral nozzle forces are known to cause severe structural damage to any new rocket engine in development during test. While three-dimensional, transient, turbulent, chemically reacting computational fluid dynamics methodology has been demonstrated to capture major side load physics with rigid nozzles, hot-fire tests often show nozzle structure deformation during major side load events, leading to structural damages if structural strengthening measures were not taken. The modeling picture is incomplete without the capability to address the two-way responses between the structure and fluid. The objective of this study is to develop a tightly coupled aeroelastic modeling algorithm by implementing the necessary structural dynamics component into an anchored computational fluid dynamics methodology. The computational fluid dynamics component is based on an unstructured-grid, pressure-based computational fluid dynamics formulation, while the computational structural dynamics component is developed under the framework of modal analysis. Transient aeroelastic nozzle startup analyses at sea level were performed, and the computed transient nozzle fluid-structure interaction physics presented,
Transient analysis using conical shell elements
NASA Technical Reports Server (NTRS)
Yang, J. C. S.; Goeller, J. E.; Messick, W. T.
1973-01-01
The use of the NASTRAN conical shell element in static, eigenvalue, and direct transient analyses is demonstrated. The results of a NASTRAN static solution of an externally pressurized ring-stiffened cylinder agree well with a theoretical discontinuity analysis. Good agreement is also obtained between the NASTRAN direct transient response of a uniform cylinder to a dynamic end load and one-dimensional solutions obtained using a method of characteristics stress wave code and a standing wave solution. Finally, a NASTRAN eigenvalue analysis is performed on a hydroballistic model idealized with conical shell elements.
NASA Technical Reports Server (NTRS)
Padovan, Joe
1987-01-01
In a three-part series of papers, a generalized finite element analysis scheme is developed to handle the steady and transient response of moving/rolling nonlinear viscoelastic structure. This paper considers the development of the moving/rolling element strategy, including the effects of large deformation kinematics and viscoelasticity modeled by fractional integrodifferential operators. To improve the solution strategy, a special hierarchical constraint procedure is developed for the case of steady rolling/translating, as well as a transient scheme involving the use of a Grunwaldian representation of the fractional operator.
NASA Astrophysics Data System (ADS)
Yang, Shuang-Long; Liang, Li-Ping; Liu, Hou-De; Xu, Ke-Jun
2018-03-01
Aiming at reducing the estimation error of the sensor frequency response function (FRF) estimated by the commonly used window-based spectral estimation method, the error models of interpolation and transient errors are derived in the form of non-parameter models. Accordingly, window effects on the errors are analyzed and reveal that the commonly used hanning window leads to smaller interpolation error which can also be significantly eliminated by the cubic spline interpolation method when estimating the FRF from the step response data, and window with smaller front-end value can restrain more transient error. Thus, a new dual-cosine window with its non-zero discrete Fourier transform bins at -3, -1, 0, 1, and 3 is constructed for FRF estimation. Compared with the hanning window, the new dual-cosine window has the equivalent interpolation error suppression capability and better transient error suppression capability when estimating the FRF from the step response; specifically, it reduces the asymptotic property of the transient error from O(N-2) of the hanning window method to O(N-4) while only increases the uncertainty slightly (about 0.4 dB). Then, one direction of a wind tunnel strain gauge balance which is a high order, small damping, and non-minimum phase system is employed as the example for verifying the new dual-cosine window-based spectral estimation method. The model simulation result shows that the new dual-cosine window method is better than the hanning window method for FRF estimation, and compared with the Gans method and LPM method, it has the advantages of simple computation, less time consumption, and short data requirement; the actual data calculation result of the balance FRF is consistent to the simulation result. Thus, the new dual-cosine window is effective and practical for FRF estimation.
Ocean Circulation-Cloud Interactions Reduce the Pace of Transient Climate Change
NASA Astrophysics Data System (ADS)
Trossman, D.; Palter, J. B.; Merlis, T. M.; Huang, Y.; Xia, Y.
2016-12-01
We argue that a substantial fraction of the uncertainty in the cloud radiative feedback during transient climate change may be due to uncertainty in the ocean circulation perturbation. A suite of climate model simulations in which the ocean circulation, the cloud radiative feedback, or a combination of both are held fixed while CO2 doubles, shows that changes in the ocean circulation reduce the amount of transient global warming caused by the radiative cloud feedback. Specifically, a slowdown in the Atlantic Meridional Overturning Circulation (AMOC) helps to maintain low cloud cover in the Northern Hemisphere extratropics. We propose that the AMOC decline increases the meridional SST gradient, strengthening the storm track, its attendant clouds and the amount of shortwave radiation they reflect back to space. If the results of our model were to scale proportionately in the CMIP5 models, whose AMOC decline ranges from 15 to 60% under RCP8.5, then as much as 70% of the intermodel spread in the cloud radiative feedback and 35% of the spread in the transient climate response could possibly stem from the model representations of AMOC decline.
Calculation of Transient Potential Rise on the Wind Turbine Struck by Lightning
Xiaoqing, Zhang
2014-01-01
A circuit model is proposed in this paper for calculating the transient potential rise on the wind turbine struck by lightning. The model integrates the blade, sliding contact site, and tower and grounding system of the wind turbine into an equivalent circuit. The lightning current path from the attachment point to the ground can be fully described by the equivalent circuit. The transient potential responses are obtained in the different positions on the wind turbine by solving the circuit equations. In order to check the validity of the model, the laboratory measurement is made with a reduced-scale wind turbine. The measured potential waveform is compared with the calculated one and a better agreement is shown between them. The practical applicability of the model is also examined by a numerical example of a 2 MW Chinese-built wind turbine. PMID:25254231
"Hit-and-Run" leaves its mark: catalyst transcription factors and chromatin modification.
Varala, Kranthi; Li, Ying; Marshall-Colón, Amy; Para, Alessia; Coruzzi, Gloria M
2015-08-01
Understanding how transcription factor (TF) binding is related to gene regulation is a moving target. We recently uncovered genome-wide evidence for a "Hit-and-Run" model of transcription. In this model, a master TF "hits" a target promoter to initiate a rapid response to a signal. As the "hit" is transient, the model invokes recruitment of partner TFs to sustain transcription over time. Following the "run", the master TF "hits" other targets to propagate the response genome-wide. As such, a TF may act as a "catalyst" to mount a broad and acute response in cells that first sense the signal, while the recruited TF partners promote long-term adaptive behavior in the whole organism. This "Hit-and-Run" model likely has broad relevance, as TF perturbation studies across eukaryotes show small overlaps between TF-regulated and TF-bound genes, implicating transient TF-target binding. Here, we explore this "Hit-and-Run" model to suggest molecular mechanisms and its biological relevance. © 2015 The Authors. Bioessays published by WILEY Periodicals, Inc.
“Hit‐and‐Run” leaves its mark: Catalyst transcription factors and chromatin modification
Varala, Kranthi; Li, Ying; Marshall‐Colón, Amy; Para, Alessia
2015-01-01
Understanding how transcription factor (TF) binding is related to gene regulation is a moving target. We recently uncovered genome‐wide evidence for a “Hit‐and‐Run” model of transcription. In this model, a master TF “hits” a target promoter to initiate a rapid response to a signal. As the “hit” is transient, the model invokes recruitment of partner TFs to sustain transcription over time. Following the “run”, the master TF “hits” other targets to propagate the response genome‐wide. As such, a TF may act as a “catalyst” to mount a broad and acute response in cells that first sense the signal, while the recruited TF partners promote long‐term adaptive behavior in the whole organism. This “Hit‐and‐Run” model likely has broad relevance, as TF perturbation studies across eukaryotes show small overlaps between TF‐regulated and TF‐bound genes, implicating transient TF‐target binding. Here, we explore this “Hit‐and‐Run” model to suggest molecular mechanisms and its biological relevance. PMID:26108710
NASA Technical Reports Server (NTRS)
Padovan, Joe
1986-01-01
In a three part series of papers, a generalized finite element analysis scheme is developed to handle the steady and transient response of moving/rolling nonlinear viscoelastic structure. This paper considers the development of the moving/rolling element strategy, including the effects of large deformation kinematics and viscoelasticity modelled by fractional integro-differential operators. To improve the solution strategy, a special hierarchical constraint procedure is developed for the case of steady rolling/translating as well as a transient scheme involving the use of a Grunwaldian representation of the fractional operator. In the second and third parts of the paper, 3-D extensions are developed along with transient contact strategies enabling the handling of impacts with obstructions. Overall, the various developments are benchmarked via comprehensive 2- and 3-D simulations. These are correlated with experimental data to define modelling capabilities.
NASA Astrophysics Data System (ADS)
Szymanski, Marek Z.; Kulszewicz-Bajer, Irena; Faure-Vincent, Jérôme; Djurado, David
2012-05-01
Space-charge-limited current transients (also referred as time resolved dark injection) is an attractive technique for mobility measurements in low mobility materials, particularly the organic semiconductors. Transients are generally analyzed in terms of the Many-Rakavy theory, which is an approximate analytical solution of the time-dependent drift-diffusion problem after application of a voltage step. In this contribution, we perform full time-dependent drift-diffusion simulation and compare simulated and experimental transients measured on a sample of triaryl-amine based electroactive dendrimer (experimental conditions: μ≈10-5 cm2/(Vs), L=300 nm, E<105 V/cm). We have found that the Many-Rakavy theory is indeed valid for estimating the mobility value, but it fails to predict quantitatively the time-dependent current response. In order to obtain a good agreement in between simulation and experiment, trapping and quasi-ohmic contact models were needed to be taken into account. In the case of the studied electroactive dendrimer, the experimental results were apparently consistent with the constant mobility Many-Rakavy theory, but with this model, a large uncertainty of 20% was found for the mobility value. We show that this uncertainty can be significantly reduced to 10% if a field-dependent mobility is taken into account in the framework of the extended Gaussian disorder model. Finally, we demonstrate that this fitting procedure between simulated and experimental transient responses also permits to unambiguously provide the values of the contact barrier, the trap concentration, the trap depth in addition to that of the mobility of carriers.
Engineering Inertial and Primary-Frequency Response for Distributed Energy Resources: Preprint
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dall-Anese, Emiliano; Zhao, Changhong; Guggilam, Swaroop
We propose a framework to engineer synthetic-inertia and droop-control parameters for distributed energy resources (DERs) so that the system frequency in a network composed of DERs and synchronous generators conforms to prescribed transient and steady-state performance specifications. Our approach is grounded in a second-order lumped-parameter model that captures the dynamics of synchronous generators and frequency-responsive DERs endowed with inertial and droop control. A key feature of this reduced-order model is that its parameters can be related to those of the originating higher-order dynamical model. This allows one to systematically design the DER inertial and droop-control coefficients leveraging classical frequency-domain responsemore » characteristics of second-order systems. Time-domain simulations validate the accuracy of the model-reduction method and demonstrate how DER controllers can be designed to meet steady-state-regulation and transient-performance specifications.« less
Engineering Inertial and Primary-Frequency Response for Distributed Energy Resources
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dall-Anese, Emiliano; Zhao, Changhong; Guggilam, Swaroop
We propose a framework to engineer synthetic-inertia and droop-control parameters for distributed energy resources (DERs) so that the system frequency in a network composed of DERs and synchronous generators conforms to prescribed transient and steady-state performance specifications. Our approach is grounded in a second-order lumped-parameter model that captures the dynamics of synchronous generators and frequency-responsive DERs endowed with inertial and droop control. A key feature of this reduced-order model is that its parameters can be related to those of the originating higherorder dynamical model. This allows one to systematically design the DER inertial and droop-control coefficients leveraging classical frequency-domain responsemore » characteristics of second-order systems. Time-domain simulations validate the accuracy of the model-reduction method and demonstrate how DER controllers can be designed to meet steady-state-regulation and transient-performance specifications.« less
Development of higher-order modal methods for transient thermal and structural analysis
NASA Technical Reports Server (NTRS)
Camarda, Charles J.; Haftka, Raphael T.
1989-01-01
A force-derivative method which produces higher-order modal solutions to transient problems is evaluated. These higher-order solutions converge to an accurate response using fewer degrees-of-freedom (eigenmodes) than lower-order methods such as the mode-displacement or mode-acceleration methods. Results are presented for non-proportionally damped structural problems as well as thermal problems modeled by finite elements.
The $10 trillion value of better information about the transient climate response.
Hope, Chris
2015-11-13
How much is better information about climate change worth? Here, I use PAGE09, a probabilistic integrated assessment model, to find the optimal paths of CO(2) emissions over time and to calculate the value of better information about one aspect of climate change, the transient climate response (TCR). Approximately halving the uncertainty range for TCR has a net present value of about $10.3 trillion (year 2005 US$) if accomplished in time for emissions to be adjusted in 2020, falling to $9.7 trillion if accomplished by 2030. Probabilistic integrated assessment modelling is the only method we have for making estimates like these for the value of better information about the science and impacts of climate change. © 2015 The Author(s).
On the Locality of Transient Electromagnetic Soundings with a Single-Loop Configuration
NASA Astrophysics Data System (ADS)
Barsukov, P. O.; Fainberg, E. B.
2018-03-01
The possibilities of reconstructing two-dimensional (2D) cross sections based on the data of the profile soundings by the transient electromagnetic method (TEM) with a single ungrounded loop are illustrated on three-dimensional (3D) models. The process of reconstruction includes three main steps: transformation of the responses in the depth dependence of resistivity ρ(h) measured along the profile, with their subsequent stitching into the 2D pseudo section; point-by-point one-dimensional (1D) inversion of the responses with the starting model constructed based on the transformations; and correction of the 2D cross section with the use of 2.5-dimensional (2.5D) block inversion. It is shown that single-loop TEM soundings allow studying the geological media within a local domain the lateral dimensions of which are commensurate with the depth of the investigation. The structure of the medium beyond this domain insignificantly affects the sounding results. This locality enables the TEM to reconstruct the geoelectrical structure of the medium from the 2D cross sections with the minimal distortions caused by the lack of information beyond the profile of the transient response measurements.
The calcium–frequency response in the rat ventricular myocyte: an experimental and modelling study
Gattoni, Sara; Røe, Åsmund Treu; Frisk, Michael; Louch, William E.; Niederer, Steven A.
2016-01-01
Key points In the majority of species, including humans, increased heart rate increases cardiac contractility. This change is known as the force–frequency response (FFR). The majority of mammals have a positive force–frequency relationship (FFR). In rat the FFR is controversial.We derive a species‐ and temperature‐specific data‐driven model of the rat ventricular myocyte.As a measure of the FFR, we test the effects of changes in frequency and extracellular calcium on the calcium–frequency response (CFR) in our model and three altered models.The results show a biphasic peak calcium–frequency response, due to biphasic behaviour of the ryanodine receptor and the combined effect of the rapid calmodulin buffer and the frequency‐dependent increase in diastolic calcium.Alterations to the model reveal that inclusion of Ca2+/calmodulin‐dependent protein kinase II (CAMKII)‐mediated L‐type channel and transient outward K+ current activity enhances the positive magnitude calcium–frequency response, and the absence of CAMKII‐mediated increase in activity of the sarco/endoplasmic reticulum Ca2+‐ATPase induces a negative magnitude calcium–frequency response. Abstract An increase in heart rate affects the strength of cardiac contraction by altering the Ca2+ transient as a response to physiological demands. This is described by the force–frequency response (FFR), a change in developed force with pacing frequency. The majority of mammals, including humans, have a positive FFR, and cardiac contraction strength increases with heart rate. However, the rat and mouse are exceptions, with the majority of studies reporting a negative FFR, while others report either a biphasic or a positive FFR. Understanding the differences in the FFR between humans and rats is fundamental to interpreting rat‐based experimental findings in the context of human physiology. We have developed a novel model of rat ventricular electrophysiology and calcium dynamics, derived predominantly from experimental data recorded under physiological conditions. As a measure of FFR, we tested the effects of changes in stimulation frequency and extracellular calcium concentration on the simulated Ca2+ transient characteristics and showed a biphasic peak calcium–frequency relationship, consistent with recent observations of a shift from negative to positive FFR when approaching the rat physiological frequency range. We tested the hypotheses that (1) inhibition of Ca2+/calmodulin‐dependent protein kinase II (CAMKII)‐mediated increase in sarco/endoplasmic reticulum Ca2+‐ATPase (SERCA) activity, (2) CAMKII modulation of SERCA, L‐type channel and transient outward K+ current activity and (3) Na+/K+ pump dynamics play a significant role in the rat FFR. The results reveal a major role for CAMKII modulation of SERCA in the peak Ca2+–frequency response, driven most significantly by the cytosolic calcium buffering system and changes in diastolic Ca2+. PMID:26916026
Transient Analysis of Pressurization and Pneumatic Subsystems of the X-34 Main Propulsion System
NASA Technical Reports Server (NTRS)
Hedayat, A.; Knight, K. C.; Chamption, R. H., Jr.; Kennedy, Jim W. (Technical Monitor)
2000-01-01
Transient models for the pressurization, vent/relief, and pneumatic subsystems of the X-34 Main Propulsion System are presented and simulation of their operation within prescribed requirements are provided. First, using ROCket Engine Transient Simulation (ROCETS) program, pressurization subsystem operation was simulated and helium requirements and the ullage thermodynamic condition within each propellant tank were calculated. Then, Overpressurization scenarios of propellant tanks and the response of vent/relief valves were evaluated using ROCETS simulation of simultaneous operation of the pressurization and vent/relief subsystems by incorporating the valves data into the model. Finally, the ROCETS simulation of in-flight operation of pneumatic subsystem predicted the overall helium consumption, Inter-Propellant Seal (IPS) purge flowrate and thermodynamic conditions, and Spin Start power.
Structural-Vibration-Response Data Analysis
NASA Technical Reports Server (NTRS)
Smith, W. R.; Hechenlaible, R. N.; Perez, R. C.
1983-01-01
Computer program developed as structural-vibration-response data analysis tool for use in dynamic testing of Space Shuttle. Program provides fast and efficient time-domain least-squares curve-fitting procedure for reducing transient response data to obtain structural model frequencies and dampings from free-decay records. Procedure simultaneously identifies frequencies, damping values, and participation factors for noisy multiple-response records.
Single-Event Effects in High-Frequency Linear Amplifiers: Experiment and Analysis
NASA Astrophysics Data System (ADS)
Zeinolabedinzadeh, Saeed; Ying, Hanbin; Fleetwood, Zachary E.; Roche, Nicolas J.-H.; Khachatrian, Ani; McMorrow, Dale; Buchner, Stephen P.; Warner, Jeffrey H.; Paki-Amouzou, Pauline; Cressler, John D.
2017-01-01
The single-event transient (SET) response of two different silicon-germanium (SiGe) X-band (8-12 GHz) low noise amplifier (LNA) topologies is fully investigated in this paper. The two LNAs were designed and implemented in 130nm SiGe HBT BiCMOS process technology. Two-photon absorption (TPA) laser pulses were utilized to induce transients within various devices in these LNAs. Impulse response theory is identified as a useful tool for predicting the settling behavior of the LNAs subjected to heavy ion strikes. Comprehensive device and circuit level modeling and simulations were performed to accurately simulate the behavior of the circuits under ion strikes. The simulations agree well with TPA measurements. The simulation, modeling and analysis presented in this paper can be applied for any other circuit topologies for SET modeling and prediction.
Visually Evoked Potential Markers of Concussion History in Patients with Convergence Insufficiency
Poltavski, Dmitri; Lederer, Paul; Cox, Laurie Kopko
2017-01-01
ABSTRACT Purpose We investigated whether differences in the pattern visual evoked potentials exist between patients with convergence insufficiency and those with convergence insufficiency and a history of concussion using stimuli designed to differentiate between magnocellular (transient) and parvocellular (sustained) neural pathways. Methods Sustained stimuli included 2-rev/s, 85% contrast checkerboard patterns of 1- and 2-degree check sizes, whereas transient stimuli comprised 4-rev/s, 10% contrast vertical sinusoidal gratings with column width of 0.25 and 0.50 cycles/degree. We tested two models: an a priori clinical model based on an assumption of at least a minimal (beyond instrumentation’s margin of error) 2-millisecond lag of transient response latencies behind sustained response latencies in concussed patients and a statistical model derived from the sample data. Results Both models discriminated between concussed and nonconcussed groups significantly above chance (with 76% and 86% accuracy, respectively). In the statistical model, patients with mean vertical sinusoidal grating response latencies greater than 119 milliseconds to 0.25-cycle/degree stimuli (or mean vertical sinusoidal latencies >113 milliseconds to 0.50-cycle/degree stimuli) and mean vertical sinusoidal grating amplitudes of less than 14.75 mV to 0.50-cycle/degree stimuli were classified as having had a history of concussion. The resultant receiver operating characteristic curve for this model had excellent discrimination between the concussed and nonconcussed (area under the curve = 0.857; P < .01) groups with sensitivity of 0.92 and specificity of 0.80. Conclusions The results suggest a promising electrophysiological approach to identifying individuals with convergence insufficiency and a history of concussion. PMID:28609417
Understanding the Implications of a LINAC’s Microstructure on Devices and Photocurrent Models
McLain, Michael Lee; McDonald, Joseph Kyle; Hembree, Charles E.; ...
2017-10-20
Here, the effect of a linear accelerator’s (LINAC’s) microstructure (i.e., train of narrow pulses) on devices and the associated transient photocurrent models are investigated. The data indicate that the photocurrent response of Si-based RF bipolar junction transistors and RF p-i-n diodes is considerably higher when taking into account the microstructure effects. Similarly, the response of diamond, SiO 2, and GaAs photoconductive detectors (standard radiation diagnostics) is higher when taking into account the microstructure. This has obvious hardness assurance implications when assessing the transient response of devices because the measured photocurrent and dose rate levels could be underestimated if microstructure effectsmore » are not captured. Indeed, the rate the energy is deposited in a material during the microstructure peaks is much higher than the filtered rate which is traditionally measured. In addition, photocurrent models developed with filtered LINAC data may be inherently inaccurate if a device is able to respond to the microstructure.« less
Understanding the Implications of a LINAC’s Microstructure on Devices and Photocurrent Models
DOE Office of Scientific and Technical Information (OSTI.GOV)
McLain, Michael Lee; McDonald, Joseph Kyle; Hembree, Charles E.
Here, the effect of a linear accelerator’s (LINAC’s) microstructure (i.e., train of narrow pulses) on devices and the associated transient photocurrent models are investigated. The data indicate that the photocurrent response of Si-based RF bipolar junction transistors and RF p-i-n diodes is considerably higher when taking into account the microstructure effects. Similarly, the response of diamond, SiO 2, and GaAs photoconductive detectors (standard radiation diagnostics) is higher when taking into account the microstructure. This has obvious hardness assurance implications when assessing the transient response of devices because the measured photocurrent and dose rate levels could be underestimated if microstructure effectsmore » are not captured. Indeed, the rate the energy is deposited in a material during the microstructure peaks is much higher than the filtered rate which is traditionally measured. In addition, photocurrent models developed with filtered LINAC data may be inherently inaccurate if a device is able to respond to the microstructure.« less
Experimentally validated finite element model of electrocaloric multilayer ceramic structures
DOE Office of Scientific and Technical Information (OSTI.GOV)
Smith, N. A. S., E-mail: nadia.smith@npl.co.uk, E-mail: maciej.rokosz@npl.co.uk, E-mail: tatiana.correia@npl.co.uk; Correia, T. M., E-mail: nadia.smith@npl.co.uk, E-mail: maciej.rokosz@npl.co.uk, E-mail: tatiana.correia@npl.co.uk; Rokosz, M. K., E-mail: nadia.smith@npl.co.uk, E-mail: maciej.rokosz@npl.co.uk, E-mail: tatiana.correia@npl.co.uk
2014-07-28
A novel finite element model to simulate the electrocaloric response of a multilayer ceramic capacitor (MLCC) under real environment and operational conditions has been developed. The two-dimensional transient conductive heat transfer model presented includes the electrocaloric effect as a source term, as well as accounting for radiative and convective effects. The model has been validated with experimental data obtained from the direct imaging of MLCC transient temperature variation under application of an electric field. The good agreement between simulated and experimental data, suggests that the novel experimental direct measurement methodology and the finite element model could be used to supportmore » the design of optimised electrocaloric units and operating conditions.« less
Transient Postseismic Relaxation With Burger's Body Viscoelasticity
NASA Astrophysics Data System (ADS)
Hetland, E. A.; Hager, B. H.; O'Connell, R. J.
2002-12-01
Typical models used to investigate postseismic deformation are composed of an elastic layer over a Maxwell viscoelastic region. Geodetic observations made after a number of large earthquakes show a rapid exponential decay in postseismic velocity immediately after the rupture, followed by a more slowly decaying (or constant) velocity at a later time. Models of a Maxwell viscoelastic interior predict a single exponential postseismic velocity relaxation. To account for observed rapid, short-term relaxation decay, surprisingly low viscosities in the lower-crust or upper-mantle have been proposed. To model the difference in short and long time decay rates, the Maxwell element is sometimes modified to have a non-linear rheology, which results in a lower effective viscosity immediately after the rupture, evolving to a higher effective viscosity as the co-seismic stresses relax. Incorporation of models of after-slip in the lower crust on a down-dip extension of the fault have also had some success at modeling the above observations. When real rocks are subjected to a sudden change in stress or strain, e.g., that caused by an earthquake, they exhibit a transient response. The transient deformation is typically accommodated by grain boundary sliding and the longer-time deformation is accommodated by motion of dislocations. Both a short-term transient response and long-term steady creep are exhibited by a Burger's body, a Maxwell element (a spring in series with a viscous dash-pot) in series with a Voigt element (a spring in parallel with a viscous dash-pot). Typically the (transient) viscosity of the Voigt element is 10 - 100 times less than the (steady) viscosity of the Maxwell element. Thus, with a Burger's body, stress relaxation is a superposition of two exponential decays. For a model composed of an elastic layer over a viscoelastic region, the coseismic changes in stress (and strain) depend only on the elastic moduli, and are independent of the description of the viscous component of the rheology. In a Burger's body model of viscoelasticity, if the viscosity of the Voigt element is much less than that of the Maxwell element, the initial relaxation time is given by the decay time τ = η {Voigt}}/G{ {Maxwell}. Whereas, for a Maxwell rheology, the initial relaxation time is given by τ = η {Maxwell}}/G{ {Maxwell}. For both models, the initial spatial distribution of stresses is the same, which results in identical initial spatial distribution of velocities. Thus it is easy to mistake the transient response of a Burger's body for that of a Maxwell rheology with unrealistically low viscosity. Only later in the seismic cycle do the spatial patterns of velocity differ for the two rheologies.
Transient response to three-phase faults on a wind turbine generator. Ph.D. Thesis - Toledo Univ.
NASA Technical Reports Server (NTRS)
Gilbert, L. J.
1978-01-01
In order to obtain a measure of its responses to short circuits a large horizontal axis wind turbine generator was modeled and its performance was simulated on a digital computer. Simulation of short circuit faults on the synchronous alternator of a wind turbine generator, without resort to the classical assumptions generally made for that analysis, indicates that maximum clearing times for the system tied to an infinite bus are longer than the typical clearing times for equivalent capacity conventional machines. Also, maximum clearing times are independent of tower shadow and wind shear. Variation of circuit conditions produce the modifications in the transient response predicted by analysis.
Thermal Response Of Composite Insulation
NASA Technical Reports Server (NTRS)
Stewart, David A.; Leiser, Daniel B.; Smith, Marnell; Kolodziej, Paul
1988-01-01
Engineering model gives useful predictions. Pair of reports presents theoretical and experimental analyses of thermal responses of multiple-component, lightweight, porous, ceramic insulators. Particular materials examined destined for use in Space Shuttle thermal protection system, test methods and heat-transfer theory useful to chemical, metallurgical, and ceramic engineers needing to calculate transient thermal responses of refractory composites.
A simplified model for equilibrium and transient swelling of thermo-responsive gels.
Drozdov, A D; deClaville Christiansen, J
2017-11-01
A simplified model is developed for the elastic response of thermo-responsive gels subjected to swelling under an arbitrary deformation with finite strains. The constitutive equations involve five adjustable parameters that are determined by fitting observations in equilibrium water uptake tests and T-jump transient tests on thin gel disks. Two scenarios for water release under heating are revealed by means of numerical simulation. When the final temperature in a T-jump test is below the volume-phase transition temperature, deswelling is characterized by smooth distribution of water molecules and small tensile stresses. When the final temperature exceeds the critical temperature, a gel disk is split into three regions (central part with a high concentration of water molecules and two domains near the boundaries with low water content) separated by sharp interfaces, whose propagation is accompanied by development of large (comparable with the elastic modulus) tensile stresses. Copyright © 2017 Elsevier Ltd. All rights reserved.
Fast-responding property of electromagnetically induced transparency in Rydberg atoms
NASA Astrophysics Data System (ADS)
Zhang, Qi; Bai, Zhengyang; Huang, Guoxiang
2018-04-01
We investigate the transient optical response property of an electromagnetically induced transparency (EIT) in a cold Rydberg atomic gas. We show that both the transient behavior and the steady-state EIT spectrum of the system depend strongly on Rydberg interaction. Especially, the response speed of the Rydberg-EIT can be five times faster (and even higher) than the conventional EIT without the Rydberg interaction. For comparison, two different theoretical approaches (i.e., two-atom model and many-atom model) are considered, revealing that Rydberg blockade effect plays a significant role for increasing the response speed of the Rydberg-EIT. The fast-responding Rydberg-EIT by using the strong, tunable Rydberg interaction uncovered here is not only helpful for enhancing the understanding of the many-body dynamics of Rydberg atoms but also useful for practical applications in quantum information processing by using Rydberg atoms.
Advanced Computational Modeling Approaches for Shock Response Prediction
NASA Technical Reports Server (NTRS)
Derkevorkian, Armen; Kolaini, Ali R.; Peterson, Lee
2015-01-01
Motivation: (1) The activation of pyroshock devices such as explosives, separation nuts, pin-pullers, etc. produces high frequency transient structural response, typically from few tens of Hz to several hundreds of kHz. (2) Lack of reliable analytical tools makes the prediction of appropriate design and qualification test levels a challenge. (3) In the past few decades, several attempts have been made to develop methodologies that predict the structural responses to shock environments. (4) Currently, there is no validated approach that is viable to predict shock environments overt the full frequency range (i.e., 100 Hz to 10 kHz). Scope: (1) Model, analyze, and interpret space structural systems with complex interfaces and discontinuities, subjected to shock loads. (2) Assess the viability of a suite of numerical tools to simulate transient, non-linear solid mechanics and structural dynamics problems, such as shock wave propagation.
Development of time-domain differential Raman for transient thermal probing of materials
Xu, Shen; Wang, Tianyu; Hurley, David; ...
2015-01-01
A novel transient thermal characterization technology is developed based on the principles of transient optical heating and Raman probing: time-domain differential Raman. It employs a square-wave modulated laser of varying duty cycle to realize controlled heating and transient thermal probing. Very well defined extension of the heating time in each measurement changes the temperature evolution profile and the probed temperature field at μs resolution. Using this new technique, the transient thermal response of a tipless Si cantilever is investigated along the length direction. A physical model is developed to reconstruct the Raman spectrum considering the temperature evolution, while taking intomore » account the temperature dependence of the Raman emission. By fitting the variation of the normalized Raman peak intensity, wavenumber, and peak area against the heating time, the thermal diffusivity is determined as 9.17 × 10⁻⁵, 8.14 × 10⁻⁵, and 9.51 × 10⁻⁵ m²/s. These results agree well with the reference value of 8.66 × 10⁻⁵ m²/s considering the 10% fitting uncertainty. The time-domain differential Raman provides a novel way to introduce transient thermal excitation of materials, probe the thermal response, and measure the thermal diffusivity, all with high accuracy.« less
Role of the ocean's AMOC in setting the uptake efficiency of transient tracers
NASA Astrophysics Data System (ADS)
Romanou, A.; Marshall, J.; Kelley, M.; Scott, J. R.
2017-12-01
The central role played by the ocean's Atlantic Meridional Overturning Circulation (AMOC) in the uptake and sequestration of transient tracers is studied in a series of experiments with the Goddard Institute for Space Studies and Massachusetts Institute of Technology ocean circulation models. Forced by observed atmospheric time series of CFC-11, both models exhibit realistic distributions in the ocean, with similar surface biases but different response over time. To better understand what controls uptake, we ran idealized forcing experiments in which the AMOC strength varied over a wide range, bracketing the observations. We found that differences in the strength and vertical scale of the AMOC largely accounted for the different rates of CFC-11 uptake and vertical distribution thereof. A two-box model enables us to quantify and relate uptake efficiency of passive tracers to AMOC strength and how uptake efficiency decreases in time. We also discuss the relationship between passive tracer and heat uptake efficiency, of which the latter controls the transient climate response to anthropogenic forcing in the North Atlantic. We find that heat uptake efficiency is substantially less (by about a factor of 5) than that for a passive tracer.
NASA Astrophysics Data System (ADS)
Wang, Yong; Tao, Zhengwu; Chen, Liang; Ma, Xin
2017-10-01
Carbonate reservoir is one of the important reservoirs in the world. Because of the characteristics of carbonate reservoir, horizontal well has become a key technology for efficiently developing carbonate reservoir. Establishing corresponding mathematical models and analyzing transient pressure behaviors of this type of well-reservoir configuration can provide a better understanding of fluid flow patterns in formation as well as estimations of important parameters. A mathematical model for a oil-water two-phase flow horizontal well in triple media carbonate reservoir by conceptualizing vugs as spherical shapes are presented in this article. A semi-analytical solution is obtained in the Laplace domain using source function theory, Laplace transformation, and superposition principle. Analysis of transient pressure responses indicates that seven characteristic flow periods of horizontal well in triple media carbonate reservoir can be identified. Parametric analysis shows that water saturation of matrix, vug and fracture system, horizontal section length, and horizontal well position can significantly influence the transient pressure responses of horizontal well in triple media carbonate reservoir. The model presented in this article can be applied to obtain important parameters pertinent to reservoir by type curve matching.
Analgesia induced by morphine microinjected into the nucleus raphe magnus: effects on tonic pain.
Dualé, Christian; Sierralta, Fernando; Dallel, Radhouane
2007-07-01
One of the possible sites of action of the analgesic effect of morphine is the Nucleus Raphe Magnus, as morphine injected into this structure induces analgesia in transient pain models. In order to test if morphine in the Nucleus Raphe Magnus is also analgesic in a tonic pain model, 5 microg of morphine or saline (control) were microinjected into the Nucleus Raphe Magnus of the rat. Analgesic effects were assessed following nociceptive stimulation using transient heating of the tail (phasic pain) and subcutaneous orofacial injection of 1.5 % formalin (tonic pain). While morphine was strongly analgesic for the tail-flick response (p <0.0001 compared to control), analgesia on the response to formalin was also observed for both early (p = 0.007) and late responses (p = 0.02). However, the response to formalin was not completely blunted. These results suggest that the Nucleus Raphe Magnus is not the exclusive site of action of morphine-induced analgesia in clinical conditions.
NASA Astrophysics Data System (ADS)
Chevalier, A.; Rejiba, F.; Schamper, C.; Thiesson, J.; Hovhannissian, G.
2016-12-01
From airborne applications to field scale measurements of Transient Electromagnetic Methods(TEM), an accurate knowledge of the sensitivity of the inductive coil sensors (system response) is aprerequisite to interpret the measured transient magnetic flux density into a subsurface distributionof conductivity. The system response is a term that refers to the cumulative effect of inductive andcapacitive couplings (cross-talks) between each component constituting a TEM apparatus and thenearby conductive structures. As a result, the frequency sensitivity of the voltage coil sensor (Rx)along with the emitted current waveform in the current emitting coil (Tx) are controlled by thegeometry and electronic characteristic of the set-up as well as the near surface electromagneticproperties. During the early development of an innovative airborne TEM solutions (French nationalTEMas project), determining the coil geometries and the impedance matching between all parts ofthe transmission link (electronic parts and coils) for various environmental set-ups, has been a majorissue. In this study, we review the required theoretical framework and propose a versatile numericalmethodology to ease the coil design and impedance matching process while extending ourunderstanding of short-time transient that operates from DC to moderately high frequencies (0 to 20Mhz). We used a full Maxwell equations FDTD model along with a semi-analytical 1D modeler to infercoils emitting and receiving properties, for various coil geometries and site-dependent conditions.Results highlight the influence of the environment on the emitting and sensing properties. Theincreasing effects of cross-talks between the Tx and the Rx coils depending on their size is shown.Strategies regarding the impedance adaptation between the electronical components and the coilsensors are then discussed for different geophysical specifications.
NASA Astrophysics Data System (ADS)
Sundberg, Marshall; Cooper, Reid F.
2010-07-01
A new viscoelastic creep function that incorporates both the effects of elastically-accommodated grain boundary sliding (GBS) and transient diffusion creep is proposed. It is demonstrated that this model can simultaneously describe both the transient microcreep curves and the shear attenuation/modulus dispersion in a fine-grained (d ∼ 5 µm) peridotite (olivine + 39 vol. % orthopyroxene) specimen. Low-frequency shear attenuation, ? , and modulus dispersion, G(ω), spectra were measured in a one-atmosphere reciprocating torsion apparatus at temperatures of 1200 ≤ T ≤ 1300°C and frequencies of 10-2.25 ≤ f ≤ 100 Hz. Reciprocating tests were complemented by a series of small stress (τ ∼ 90 kPa) microcreep experiments at the same temperatures. In contrast to previous models where the parameters of viscoelastic models are derived by fitting the Laplace transform of the creep function to measured attenuation spectra, the parameters are derived solely from the fit of the creep function to the experimental microcreep curves using different published expressions for the relaxation strength of elastically-accommodated GBS. This approach may allow future studies to better link the large dataset of steady-state creep response to the dynamic attenuation behavior.
Application of Discrete Huygens Method for Diffraction of Transient Ultrasonic Field
NASA Astrophysics Data System (ADS)
Alia, A.
2018-01-01
Several time-domain methods have been widely used to predict impulse response in acoustics. Despite its great potential, Discrete Huygens Method (DHM) has not been as widely used in the domain of ultrasonic diffraction as in other fields. In fact, little can be found in literature about the application of the DHM to diffraction phenomenon that can be described in terms of direct and edge waves, a concept suggested by Young since 1802. In this paper, a simple axisymmetric DHM-model has been used to simulate the transient ultrasonic field radiation of a baffled transducer and its diffraction by a target located on axis. The results are validated by impulse response based calculations. They indicate the capability of DHM to simulate diffraction occurring at transducer and target edges and to predict the complicated transient field in pulse mode.
NASA Astrophysics Data System (ADS)
Shi, Zongyang; Liu, Lihua; Xiao, Pan; Geng, Zhi; Liu, Fubo; Fang, Guangyou
2018-02-01
An ungrounded loop in the shallow subsurface transient electromagnetic surveys has been studied as the transmission line model for early turn-off stage, which can accurately explicate the early turn-off current waveform inconsistency along the loop. In this paper, the Gauss-Legendre numerical integration method is proposed for the first time to simulate and analyze the transient electromagnetic (TEM) response considering the different early turn-off current waveforms along the loop. During the simulation, these integral node positions along the loop are firstly determined by solving these zero points of Legendre polynomial, then the turn-off current of each node position is simulated by using the transfer function of the transmission line. Finally, the total TEM response is calculated by using the Gauss-Legendre integral formula. In addition, the comparison and analysis between the results affected by the distributed parameters and that generated by lumped parameters are presented. It is found that the TEM responses agree well with each other after current is thoroughly switched off, while the transient responses in turn-off stage are completely different. It means that the position dependence of the early turn-off current should be introduced into the forward model during the early response data interpretation of the shallow TEM detection of the ungrounded loop. Furthermore, the TEM response simulations at four geometric symmetry points are made. It shows that early responses of different geometric symmetry points are also inconsistent. The research on the influence of turn-off current position dependence on the early response of geometric symmetry point is of great significance to guide the layout of the survey lines and the transmitter location.
Temporal and spatial adaptation of transient responses to local features
O'Carroll, David C.; Barnett, Paul D.; Nordström, Karin
2012-01-01
Interpreting visual motion within the natural environment is a challenging task, particularly considering that natural scenes vary enormously in brightness, contrast and spatial structure. The performance of current models for the detection of self-generated optic flow depends critically on these very parameters, but despite this, animals manage to successfully navigate within a broad range of scenes. Within global scenes local areas with more salient features are common. Recent work has highlighted the influence that local, salient features have on the encoding of optic flow, but it has been difficult to quantify how local transient responses affect responses to subsequent features and thus contribute to the global neural response. To investigate this in more detail we used experimenter-designed stimuli and recorded intracellularly from motion-sensitive neurons. We limited the stimulus to a small vertically elongated strip, to investigate local and global neural responses to pairs of local “doublet” features that were designed to interact with each other in the temporal and spatial domain. We show that the passage of a high-contrast doublet feature produces a complex transient response from local motion detectors consistent with predictions of a simple computational model. In the neuron, the passage of a high-contrast feature induces a local reduction in responses to subsequent low-contrast features. However, this neural contrast gain reduction appears to be recruited only when features stretch vertically (i.e., orthogonal to the direction of motion) across at least several aligned neighboring ommatidia. Horizontal displacement of the components of elongated features abolishes the local adaptation effect. It is thus likely that features in natural scenes with vertically aligned edges, such as tree trunks, recruit the greatest amount of response suppression. This property could emphasize the local responses to such features vs. those in nearby texture within the scene. PMID:23087617
How Does a Divided Population Respond to Change?
Qubbaj, Murad R.; Muneepeerakul, Rachata; Aggarwal, Rimjhim M.; Anderies, John M.
2015-01-01
Most studies on the response of socioeconomic systems to a sudden shift focus on long-term equilibria or end points. Such narrow focus forgoes many valuable insights. Here we examine the transient dynamics of regime shift on a divided population, exemplified by societies divided ideologically, politically, economically, or technologically. Replicator dynamics is used to investigate the complex transient dynamics of the population response. Though simple, our modeling approach exhibits a surprisingly rich and diverse array of dynamics. Our results highlight the critical roles played by diversity in strategies and the magnitude of the shift. Importantly, it allows for a variety of strategies to arise organically as an integral part of the transient dynamics—as opposed to an independent process—of population response to a regime shift, providing a link between the population's past and future diversity patterns. Several combinations of different populations' strategy distributions and shifts were systematically investigated. Such rich dynamics highlight the challenges of anticipating the response of a divided population to a change. The findings in this paper can potentially improve our understanding of a wide range of socio-ecological and technological transitions. PMID:26161859
How Does a Divided Population Respond to Change?
Qubbaj, Murad R; Muneepeerakul, Rachata; Aggarwal, Rimjhim M; Anderies, John M
2015-01-01
Most studies on the response of socioeconomic systems to a sudden shift focus on long-term equilibria or end points. Such narrow focus forgoes many valuable insights. Here we examine the transient dynamics of regime shift on a divided population, exemplified by societies divided ideologically, politically, economically, or technologically. Replicator dynamics is used to investigate the complex transient dynamics of the population response. Though simple, our modeling approach exhibits a surprisingly rich and diverse array of dynamics. Our results highlight the critical roles played by diversity in strategies and the magnitude of the shift. Importantly, it allows for a variety of strategies to arise organically as an integral part of the transient dynamics--as opposed to an independent process--of population response to a regime shift, providing a link between the population's past and future diversity patterns. Several combinations of different populations' strategy distributions and shifts were systematically investigated. Such rich dynamics highlight the challenges of anticipating the response of a divided population to a change. The findings in this paper can potentially improve our understanding of a wide range of socio-ecological and technological transitions.
Fluid-solid coupled simulation of the ignition transient of solid rocket motor
NASA Astrophysics Data System (ADS)
Li, Qiang; Liu, Peijin; He, Guoqiang
2015-05-01
The first period of the solid rocket motor operation is the ignition transient, which involves complex processes and, according to chronological sequence, can be divided into several stages, namely, igniter jet injection, propellant heating and ignition, flame spreading, chamber pressurization and solid propellant deformation. The ignition transient should be comprehensively analyzed because it significantly influences the overall performance of the solid rocket motor. A numerical approach is presented in this paper for simulating the fluid-solid interaction problems in the ignition transient of the solid rocket motor. In the proposed procedure, the time-dependent numerical solutions of the governing equations of internal compressible fluid flow are loosely coupled with those of the geometrical nonlinearity problems to determine the propellant mechanical response and deformation. The well-known Zeldovich-Novozhilov model was employed to model propellant ignition and combustion. The fluid-solid coupling interface data interpolation scheme and coupling instance for different computational agents were also reported. Finally, numerical validation was performed, and the proposed approach was applied to the ignition transient of one laboratory-scale solid rocket motor. For the application, the internal ballistics were obtained from the ground hot firing test, and comparisons were made. Results show that the integrated framework allows us to perform coupled simulations of the propellant ignition, strong unsteady internal fluid flow, and propellant mechanical response in SRMs with satisfactory stability and efficiency and presents a reliable and accurate solution to complex multi-physics problems.
NASA Astrophysics Data System (ADS)
Kinsey, J. E.; Waltz, R. E.; DeBoo, J. C.
1999-05-01
It is difficult to discriminate between various tokamak transport models using standardized statistical measures to assess the goodness of fit with steady-state density and temperature profiles in tokamaks. This motivates consideration of transient transport experiments as a technique for testing the temporal response predicted by models. Results are presented comparing the predictions from the Institute for Fusion Studies—Princeton Plasma Physics Laboratory (IFS/PPPL), gyro-Landau-fluid (GLF23), Multi-mode (MM), Current Diffusive Ballooning Mode (CDBM), and Mixed-shear (MS) transport models against data from ohmic cold pulse and modulated electron cyclotron heating (ECH) experiments. In ohmically heated discharges with rapid edge cooling due to trace impurity injection, it is found that critical gradient models containing a strong temperature ratio (Ti/Te) dependence can exhibit behavior that is qualitatively consistent both spatially and temporally with experimental observation while depending solely on local parameters. On the DIII-D tokamak [J. L. Luxon and L. G. Davis, Fusion Technol. 8, 441 (1985)], off-axis modulated ECH experiments have been conducted in L-mode (low confinement mode) and the perturbed electron and ion temperature response to multiple heat pulses has been measured across the plasma core. Comparing the predicted Fourier phase of the temperature perturbations, it is found that no single model yielded agreement with both electron and ion phases for all cases. In general, it was found that the IFS/PPPL, GLF23, and MS models agreed well with the ion response, but not with the electron response. The CDBM and MM models agreed well with the electron response, but not with the ion response. For both types of transient experiments, temperature coupling between the electron and ion transport is found to be an essential feature needed in the models for reproducing the observed perturbative response.
Static and dynamic deflection studies of the SRM aft case-nozzle joint
NASA Technical Reports Server (NTRS)
Christian, David C.; Kos, Lawrence D.; Torres, Isaias
1989-01-01
The redesign of the joints on the solid rocket motor (SRM) has prompted the need for analyzing the behavior of the joints using several different types of analyses. The types of analyses performed include modal analysis, static analysis, transient response analysis, and base driving response analysis. The forces used in these analyses to drive the mathematical model include SRM internal chamber pressure, nozzle blowout and side forces, shuttle vehicle lift-off dynamics, SRM pressure transient rise curve, gimbal forces and moments, actuator gimbal loads, and vertical and radial bolt preloads. The math model represented the SRM from the aft base tangent point (1,823.95 in) all the way back to the nozzle, where a simplified, tuned nozzle model was attached. The new design used the radial bolts as an additional feature to reduce the gap opening at the aft dome/nozzle fixed housing interface.
Transient response of a liquid injector to a steep-fronted transverse pressure wave
NASA Astrophysics Data System (ADS)
Lim, D.; Heister, S.; Stechmann, D.; Kan, B.
2017-12-01
Motivated by the dynamic injection environment posed by unsteady pressure gain combustion processes, an experimental apparatus was developed to visualize the dynamic response of a transparent liquid injector subjected to a single steep-fronted transverse pressure wave. Experiments were conducted at atmospheric pressure with a variety of acrylic injector passage designs using water as the working fluid. High-speed visual observations were made of the injector exit near field, and the extent of backflow and the time to refill the orifice passage were characterized over a range of injection pressures. A companion transient one-dimensional model was developed for interpretation of the results and to elucidate the trends with regard to the strength of the transverse pressure wave. Results from the model were compared with the experimental observations.
Transient response of a liquid injector to a steep-fronted transverse pressure wave
NASA Astrophysics Data System (ADS)
Lim, D.; Heister, S.; Stechmann, D.; Kan, B.
2018-07-01
Motivated by the dynamic injection environment posed by unsteady pressure gain combustion processes, an experimental apparatus was developed to visualize the dynamic response of a transparent liquid injector subjected to a single steep-fronted transverse pressure wave. Experiments were conducted at atmospheric pressure with a variety of acrylic injector passage designs using water as the working fluid. High-speed visual observations were made of the injector exit near field, and the extent of backflow and the time to refill the orifice passage were characterized over a range of injection pressures. A companion transient one-dimensional model was developed for interpretation of the results and to elucidate the trends with regard to the strength of the transverse pressure wave. Results from the model were compared with the experimental observations.
NASA Technical Reports Server (NTRS)
Balakrishna, S.; Goglia, G. L.
1979-01-01
The details of the efforts to synthesize a control-compatible multivariable model of a liquid nitrogen cooled, gaseous nitrogen operated, closed circuit, cryogenic pressure tunnel are presented. The synthesized model was transformed into a real-time cryogenic tunnel simulator, and this model is validated by comparing the model responses to the actual tunnel responses of the 0.3 m transonic cryogenic tunnel, using the quasi-steady-state and the transient responses of the model and the tunnel. The global nature of the simple, explicit, lumped multivariable model of a closed circuit cryogenic tunnel is demonstrated.
Joshi, Shailendra; Singh-Moon, Rajinder; Wang, Mei; Bruce, Jeffrey N.; Bigio, Irving J.; Mayevsky, Avraham
2014-01-01
Disruption of blood brain barrier (BBB) is used to enhance chemotherapeutic drug delivery. The purpose of this study was to understand the time course of hemodynamic and metabolic response to intraarterial (IA) mannitol infusions in order to optimize the delivery of drugs for treating brain tumors. Principal results We compared hemodynamic response, EEG changes, and mitochondrial function as judged by relative changes in tissue NADH concentrations, after intracarotid (IC) infusion of equal volumes of normal saline and mannitol in our rabbit IC drug delivery model. We observed significantly greater, though transient, hyperemic response to IC infusion of mannitol compared to normal saline. Infusion of mannitol also resulted in a greater increase in tissue NADH concentrations relative to the baseline. These hemodynamic, and metabolic changes returned to baseline within 5 min of mannitol injection. Conclusion Significant, though transient, changes in blood flow and brain metabolism occur with IA mannitol infusion. The observed transient hyperemia would suggest that intravenous (IV) chemotherapy should be administered either just before, or concurrent with IA mannitol injections. On the other hand, IA chemotherapy should be delayed until the peak hyperemic response has subsided. PMID:24440631
Golan-Lavi, Roni; Giacomelli, Chiara; Fuks, Garold; Zeisel, Amit; Sonntag, Johanna; Sinha, Sanchari; Köstler, Wolfgang; Wiemann, Stefan; Korf, Ulrike; Yarden, Yosef; Domany, Eytan
2017-03-28
Protein responses to extracellular cues are governed by gene transcription, mRNA degradation and translation, and protein degradation. In order to understand how these time-dependent processes cooperate to generate dynamic responses, we analyzed the response of human mammary cells to the epidermal growth factor (EGF). Integrating time-dependent transcript and protein data into a mathematical model, we inferred for several proteins their pre-and post-stimulus translation and degradation coefficients and found that they exhibit complex, time-dependent variation. Specifically, we identified strategies of protein production and degradation acting in concert to generate rapid, transient protein bursts in response to EGF. Remarkably, for some proteins, for which the response necessitates rapidly decreased abundance, cells exhibit a transient increase in the corresponding degradation coefficient. Our model and analysis allow inference of the kinetics of mRNA translation and protein degradation, without perturbing cells, and open a way to understanding the fundamental processes governing time-dependent protein abundance profiles. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.
Modeling the reversible, diffusive sink effect in response to transient contaminant sources.
Zhao, D; Little, J C; Hodgson, A T
2002-09-01
A physically based diffusion model is used to evaluate the sink effect of diffusion-controlled indoor materials and to predict the transient contaminant concentration in indoor air in response to several time-varying contaminant sources. For simplicity, it is assumed the predominant indoor material is a homogeneous slab, initially free of contaminant, and the air within the room is well mixed. The model enables transient volatile organic compound (VOC) concentrations to be predicted based on the material/air partition coefficient (K) and the material-phase diffusion coefficient (D) of the sink. Model predictions are made for three scenarios, each mimicking a realistic situation in a building. Styrene, phenol, and naphthalene are used as representative VOCs. A styrene butadiene rubber (SBR) backed carpet, vinyl flooring (VF), and a polyurethane foam (PUF) carpet cushion are considered as typical indoor sinks. In scenarios involving a sinusoidal VOC input and a double exponential decaying input, the model predicts the sink has a modest impact for SBR/styrene, but the effect increases for VF/phenol and PUF/naphthalene. In contrast, for an episodic chemical spill, SBR is predicted to reduce the peak styrene concentration considerably. A parametric study reveals for systems involving a large equilibrium constant (K), the kinetic constant (D) will govern the shape of the resulting gasphase concentration profile. On the other hand, for systems with a relaxed mass transfer resistance, K will dominate the profile.
Cross-bridge elasticity in single smooth muscle cells
1983-01-01
In smooth muscle, a cross-bridge mechanism is believed to be responsible for active force generation and fiber shortening. In the present studies, the viscoelastic and kinetic properties of the cross- bridge were probed by eliciting tension transients in response to small, rapid, step length changes (delta L = 0.3-1.0% Lcell in 2 ms). Tension transients were obtained in a single smooth muscle cell isolated from the toad (Bufo marinus) stomach muscularis, which was tied between a force transducer and a displacement device. To record the transients, which were of extremely small magnitude (0.1 microN), a high-frequency (400 Hz), ultrasensitive force transducer (18 mV/microN) was designed and built. The transients obtained during maximal force generation (Fmax = 2.26 microN) were characterized by a linear elastic response (Emax = 1.26 X 10(4) mN/mm2) coincident with the length step, which was followed by a biphasic tension recovery made up of two exponentials (tau fast = 5-20 ms, tau slow = 50-300 ms). During the development of force upon activation, transients were elicited. The relationship between stiffness and force was linear, which suggests that the transients originate within the cross-bridge and reflect the cross-bridge's viscoelastic and kinetic properties. The observed fiber elasticity suggests that the smooth muscle cross-bridge is considerably more compliant than in fast striated muscle. A thermodynamic model is presented that allows for an analysis of the factors contributing to the increased compliance of the smooth muscle cross-bridge. PMID:6413640
Inverse Transient Analysis for Classification of Wall Thickness Variations in Pipelines
Tuck, Jeffrey; Lee, Pedro
2013-01-01
Analysis of transient fluid pressure signals has been investigated as an alternative method of fault detection in pipeline systems and has shown promise in both laboratory and field trials. The advantage of the method is that it can potentially provide a fast and cost effective means of locating faults such as leaks, blockages and pipeline wall degradation within a pipeline while the system remains fully operational. The only requirement is that high speed pressure sensors are placed in contact with the fluid. Further development of the method requires detailed numerical models and enhanced understanding of transient flow within a pipeline where variations in pipeline condition and geometry occur. One such variation commonly encountered is the degradation or thinning of pipe walls, which can increase the susceptible of a pipeline to leak development. This paper aims to improve transient-based fault detection methods by investigating how changes in pipe wall thickness will affect the transient behaviour of a system; this is done through the analysis of laboratory experiments. The laboratory experiments are carried out on a stainless steel pipeline of constant outside diameter, into which a pipe section of variable wall thickness is inserted. In order to detect the location and severity of these changes in wall conditions within the laboratory system an inverse transient analysis procedure is employed which considers independent variations in wavespeed and diameter. Inverse transient analyses are carried out using a genetic algorithm optimisation routine to match the response from a one-dimensional method of characteristics transient model to the experimental time domain pressure responses. The accuracy of the detection technique is evaluated and benefits associated with various simplifying assumptions and simulation run times are investigated. It is found that for the case investigated, changes in the wavespeed and nominal diameter of the pipeline are both important to the accuracy of the inverse analysis procedure and can be used to differentiate the observed transient behaviour caused by changes in wall thickness from that caused by other known faults such as leaks. Further application of the method to real pipelines is discussed.
Study on DFIG wind turbines control strategy for improving frequency response characteristics
NASA Astrophysics Data System (ADS)
Zhao, Dongmei; Wu, Di; Liu, Yanhua; Zhou, Zhiyu
2012-01-01
The active and reactive power decoupling control for the double-fed induction generator wind turbines(DFIG) does not play a positive role to the frequency response ability of power grid because it performs as the hidden inertia for the power grid. If we want to improve the transient frequency stability of the wind turbine when it is integrated with the system, we must ameliorate its frequency response characteristics. The inability of frequency control due to DFIG decoupling control could be overcome through releasing (or absorbing) a part of the kinetic energy stored in the rotor, so as to increase (or decrease) active power injected to the power system when the deviation of power system frequency appears. This paper discusses the mathematical model of the variable speed DFIG, including the aerodynamic model, pitch control system model, shaft model, generator model and inverter control model, and other key components, focusing on the mathematical model of the converters in rotor side and grid side. Based on the existing model of wind generator, the paper attaches the frequency control model on the platform of the simulation software DIgSILENT/PowerFactory. The simulation results show that the proposed control strategy can response quickly to transient frequency deviation and prove that wind farms can participate in the system frequency regulation to a certain extent. Finally, the result verifies the accuracy and plausibility of the inverter control model which attaches the frequency control module.
Study on DFIG wind turbines control strategy for improving frequency response characteristics
NASA Astrophysics Data System (ADS)
Zhao, Dongmei; Wu, Di; Liu, Yanhua; Zhou, Zhiyu
2011-12-01
The active and reactive power decoupling control for the double-fed induction generator wind turbines(DFIG) does not play a positive role to the frequency response ability of power grid because it performs as the hidden inertia for the power grid. If we want to improve the transient frequency stability of the wind turbine when it is integrated with the system, we must ameliorate its frequency response characteristics. The inability of frequency control due to DFIG decoupling control could be overcome through releasing (or absorbing) a part of the kinetic energy stored in the rotor, so as to increase (or decrease) active power injected to the power system when the deviation of power system frequency appears. This paper discusses the mathematical model of the variable speed DFIG, including the aerodynamic model, pitch control system model, shaft model, generator model and inverter control model, and other key components, focusing on the mathematical model of the converters in rotor side and grid side. Based on the existing model of wind generator, the paper attaches the frequency control model on the platform of the simulation software DIgSILENT/PowerFactory. The simulation results show that the proposed control strategy can response quickly to transient frequency deviation and prove that wind farms can participate in the system frequency regulation to a certain extent. Finally, the result verifies the accuracy and plausibility of the inverter control model which attaches the frequency control module.
ENEL overall PWR plant models and neutronic integrated computing systems
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pedroni, G.; Pollachini, L.; Vimercati, G.
1987-01-01
To support the design activity of the Italian nuclear energy program for the construction of pressurized water reactors, the Italian Electricity Board (ENEL) needs to verify the design as a whole (that is, the nuclear steam supply system and balance of plant) both in steady-state operation and in transient. The ENEL has therefore developed two computer models to analyze both operational and incidental transients. The models, named STRIP and SFINCS, perform the analysis of the nuclear as well as the conventional part of the plant (the control system being properly taken into account). The STRIP model has been developed bymore » means of the French (Electricite de France) modular code SICLE, while SFINCS is based on the Italian (ENEL) modular code LEGO. STRIP validation was performed with respect to Fessenheim French power plant experimental data. Two significant transients were chosen: load step and total load rejection. SFINCS validation was performed with respect to Saint-Laurent French power plant experimental data and also by comparing the SFINCS-STRIP responses.« less
Development of an Aeroelastic Modeling Capability for Transient Nozzle Side Load Analysis
NASA Technical Reports Server (NTRS)
Wang, Ten-See; Zhao, Xiang; Zhang, Sijun; Chen, Yen-Sen
2013-01-01
Lateral nozzle forces are known to cause severe structural damage to any new rocket engine in development during test. While three-dimensional, transient, turbulent, chemically reacting computational fluid dynamics methodology has been demonstrated to capture major side load physics with rigid nozzles, hot-fire tests often show nozzle structure deformation during major side load events, leading to structural damages if structural strengthening measures were not taken. The modeling picture is incomplete without the capability to address the two-way responses between the structure and fluid. The objective of this study is to develop a coupled aeroelastic modeling capability by implementing the necessary structural dynamics component into an anchored computational fluid dynamics methodology. The computational fluid dynamics component is based on an unstructured-grid, pressure-based computational fluid dynamics formulation, while the computational structural dynamics component is developed in the framework of modal analysis. Transient aeroelastic nozzle startup analyses of the Block I Space Shuttle Main Engine at sea level were performed. The computed results from the aeroelastic nozzle modeling are presented.
Transient processes in the combustion of nitramine propellants
NASA Technical Reports Server (NTRS)
Cohen, N. S.; Strand, L. D.
1978-01-01
A transient combustion model of nitramine propellants is combined with an isentropic compression shock formation model to determine the role of nitramine propellant combustion in DDT, excluding effects associated with propellant structural properties or mechanical behavior. The model is derived to represent the closed pipe experiment that is widely used to characterize explosives, except that the combustible material is a monolithic charge rather than compressed powder. Computations reveal that the transient combustion process cannot by itself produce DDT by this model. Compressibility of the solid at high pressure is the key factor limiting pressure buildups created by the combustion. On the other hand, combustion mechanisms which promote pressure buildups are identified and related to propellant formulation variables. Additional combustion instability data for nitramine propellants are presented. Although measured combustion response continues to be low, more data are required to distinguish HMX and active binder component contributions. A design for a closed vessel apparatus for experimental studies of high pressure combustion is discussed.
Fast luminous blue transients from newborn black holes
NASA Astrophysics Data System (ADS)
Kashiyama, Kazumi; Quataert, Eliot
2015-08-01
Newborn black holes in collapsing massive stars can be accompanied by a fallback disc. The accretion rate is typically super-Eddington and strong disc outflows are expected. Such outflows could be directly observed in some failed explosions of compact (blue supergiants or Wolf-Rayet stars) progenitors, and may be more common than long-duration gamma-ray bursts. Using an analytical model, we show that the fallback disc outflows produce blue UV-optical transients with a peak bolometric luminosity of ˜ 1042-43 erg s- 1 (peak R-band absolute AB magnitudes of -16 to -18) and an emission duration of ˜ a few to ˜10 d. The spectra are likely dominated intermediate mass elements, but will lack much radioactive nuclei and iron-group elements. The above properties are broadly consistent with some of the rapid blue transients detected by Panoramic Survey Telescope & Rapid Response System and Palomar Transient Factory. This scenario can be distinguished from alternative models using radio observations within a few years after the optical peak.
USDA-ARS?s Scientific Manuscript database
An integrated foundation is presented to study the impacts of external forcings on irrigated agricultural systems. Individually, models are presented that simulate groundwater hydrogeology and econometric farm level crop choices and irrigated water use. The natural association between groundwater we...
The calcium-frequency response in the rat ventricular myocyte: an experimental and modelling study.
Gattoni, Sara; Røe, Åsmund Treu; Frisk, Michael; Louch, William E; Niederer, Steven A; Smith, Nicolas P
2016-08-01
In the majority of species, including humans, increased heart rate increases cardiac contractility. This change is known as the force-frequency response (FFR). The majority of mammals have a positive force-frequency relationship (FFR). In rat the FFR is controversial. We derive a species- and temperature-specific data-driven model of the rat ventricular myocyte. As a measure of the FFR, we test the effects of changes in frequency and extracellular calcium on the calcium-frequency response (CFR) in our model and three altered models. The results show a biphasic peak calcium-frequency response, due to biphasic behaviour of the ryanodine receptor and the combined effect of the rapid calmodulin buffer and the frequency-dependent increase in diastolic calcium. Alterations to the model reveal that inclusion of Ca(2+) /calmodulin-dependent protein kinase II (CAMKII)-mediated L-type channel and transient outward K(+) current activity enhances the positive magnitude calcium-frequency response, and the absence of CAMKII-mediated increase in activity of the sarco/endoplasmic reticulum Ca(2+) -ATPase induces a negative magnitude calcium-frequency response. An increase in heart rate affects the strength of cardiac contraction by altering the Ca(2+) transient as a response to physiological demands. This is described by the force-frequency response (FFR), a change in developed force with pacing frequency. The majority of mammals, including humans, have a positive FFR, and cardiac contraction strength increases with heart rate. However, the rat and mouse are exceptions, with the majority of studies reporting a negative FFR, while others report either a biphasic or a positive FFR. Understanding the differences in the FFR between humans and rats is fundamental to interpreting rat-based experimental findings in the context of human physiology. We have developed a novel model of rat ventricular electrophysiology and calcium dynamics, derived predominantly from experimental data recorded under physiological conditions. As a measure of FFR, we tested the effects of changes in stimulation frequency and extracellular calcium concentration on the simulated Ca(2+) transient characteristics and showed a biphasic peak calcium-frequency relationship, consistent with recent observations of a shift from negative to positive FFR when approaching the rat physiological frequency range. We tested the hypotheses that (1) inhibition of Ca(2+) /calmodulin-dependent protein kinase II (CAMKII)-mediated increase in sarco/endoplasmic reticulum Ca(2+) -ATPase (SERCA) activity, (2) CAMKII modulation of SERCA, L-type channel and transient outward K(+) current activity and (3) Na(+) /K(+) pump dynamics play a significant role in the rat FFR. The results reveal a major role for CAMKII modulation of SERCA in the peak Ca(2+) -frequency response, driven most significantly by the cytosolic calcium buffering system and changes in diastolic Ca(2+) . © 2016 The Authors. The Journal of Physiology © 2016 The Physiological Society.
Thermal Analysis and Design of an Advanced Space Suit
NASA Technical Reports Server (NTRS)
Lin, Chin H.; Campbell, Anthony B.; French, Jonathan D.; French, D.; Nair, Satish S.; Miles, John B.
2000-01-01
The thermal dynamics and design of an Advanced Space Suit are considered. A transient model of the Advanced Space Suit has been developed and implemented using MATLAB/Simulink to help with sizing, with design evaluation, and with the development of an automatic thermal comfort control strategy. The model is described and the thermal characteristics of the Advanced Space suit are investigated including various parametric design studies. The steady state performance envelope for the Advanced Space Suit is defined in terms of the thermal environment and human metabolic rate and the transient response of the human-suit-MPLSS system is analyzed.
Model of THz Magnetization Dynamics.
Bocklage, Lars
2016-03-09
Magnetization dynamics can be coherently controlled by THz laser excitation, which can be applied in ultrafast magnetization control and switching. Here, transient magnetization dynamics are calculated for excitation with THz magnetic field pulses. We use the ansatz of Smit and Beljers, to formulate dynamic properties of the magnetization via partial derivatives of the samples free energy density, and extend it to solve the Landau-Lifshitz-equation to obtain the THz transients of the magnetization. The model is used to determine the magnetization response to ultrafast multi- and single-cycle THz pulses. Control of the magnetization trajectory by utilizing the THz pulse shape and polarization is demonstrated.
Observations on autoregulation in skeletal muscle - The effects of arterial hypoxia
NASA Technical Reports Server (NTRS)
Pohost, G. M.; Newell, J. B.; Hamlin, N. P.; Powell, W. J., Jr.
1976-01-01
An experimental study was carried out on 25 mongrel dogs of both sexes to re-evaluate autoregulation of blood flow in skeletal muscle, with particular reference to the steady-state resistance and transient response in muscle blood flow following a square wave increase in arterial perfusion pressure and to the examination of the effect of arterial hypoxia on this transient response. The data emphasize the importance of considering the transient changes in blood flow in evaluating the autoregulatory response in skeletal muscle. For quantification purposes, a parameter termed alpha is introduced which represents the ratio between the increase in blood flow from baseline to peak and the return of blood flow from the peak to the new steady-state. Such a quantification of the transient response in flow with step increases in perfusion pressure demonstrates substantial transient responses under conditions of normal oxygenation and progressive attenuation of flow transients with increasing hypoxia.
NASA Astrophysics Data System (ADS)
Wallis, D.; Hansen, L. N.; Kempton, I.; Wilkinson, A. J.
2017-12-01
Geodynamic phenomena, including glacial isostatic adjustment and postseismic deformation, can involve transient deformation in response to changes in differential stress acting on mantle rocks. As such, rheological models of transient deformation are incorporated in predictions of associated processes, including sea-level rise and stress redistribution after earthquakes. However, experimental constraints on rheological models for transient deformation of mantle materials are sparse. In particular, experiments involving stress reductions have been lacking. Moreover, a material's response to a reduction in stress can provide clues to the microphysical processes controlling deformation. To constrain models of transient deformation of mantle rocks we performed stress-reduction tests on single crystals of olivine at 1250-1300°C. Mechanical and piezoelectric actuators controlled constant initial stress during creep. At various strain intervals stress was reduced near-instantaneously using the piezoelectric actuator, inducing both elastic and anelastic (time-dependent) lengthening of the samples. A range of magnitudes of stress reduction were applied, typically unloading 10-90% of the initial stress. High-angular resolution electron backscatter diffraction (HR-EBSD), based on cross-correlation of diffraction patterns, was used to map dislocation density and elastic strain distributions in the recovered samples. Magnitudes of anelastic back-strain increase with increasing magnitudes of stress reduction and show a marked increase when stress reductions exceed 50% of the initial stress, consistent with previous observations in metals and alloys. This observation is inconsistent with the Burgers rheological model commonly used to describe transient behaviour and suggests that the style of rheological behaviour depends on the magnitude of stress change. HR-EBSD maps reveal that the crystal lattices are smoothly curved and generally lack subgrain boundaries and elastic strain heterogeneities. The dependence of the anelastic behaviour on the initial stress, combined with the lack of subgrain boundaries, suggest that the anelastic behaviour is controlled by local interactions between dislocations, rather than resistance imposed by the lattice or subgrain boundaries.
Coupled loads analysis for Space Shuttle payloads
NASA Technical Reports Server (NTRS)
Eldridge, J.
1992-01-01
Described here is a method for determining the transient response of, and the resultant loads in, a system exposed to predicted external forces. In this case, the system consists of four racks mounted on the inside of a space station resource node module (SSRNMO) which is mounted in the payload bay of the space shuttle. The predicted external forces are forcing functions which envelope worst case forces applied to the shuttle during liftoff and landing. This analysis, called a coupled loads analysis, is used to couple the payload and shuttle models together, determine the transient response of the system, and then recover payload loads, payload accelerations, and payload to shuttle interface forces.
NASA Astrophysics Data System (ADS)
Ferrier, Ken L.; West, Nicole
2017-09-01
Understanding the relationship between chemical erosion rates (W) and physical erosion rates (E) is of wide interest due to their roles in driving landscape evolution, supplying nutrients to soils and streams, and modulating the global carbon cycle. Measured relationships between W and E vary around the globe, with some regions exhibiting positive correlations between W and E, some negative correlations, and others no correlation within uncertainty. Here we use a numerical model for mineral weathering in well-mixed ridgetop regolith to explore how complex W- E relationships can be generated by simple transient perturbations in E. We show that a Gaussian perturbation in E can produce positive or negative responses in W, and can result in a variety of hysteresis loops - clockwise, counterclockwise, or figure-eight - in plots of W against E. The nature of the transient response depends on the shape of the steady-state W- E relationship, which is set by regolith mineralogy, and the ratio of E to the maximum possible regolith production rate. The response time of W is controlled by the response time of soluble mineral concentrations at low E, where soluble mineral concentrations are low, and by the response time of regolith thickness at high E, where regolith thickness is low. These complex W- E relationships arise in the absence of variations in climate and lithology, which suggests that transients may account for some of the observed differences in W- E relationships among field sites, even among sites that share the same climate and lithology.
Generation of linear dynamic models from a digital nonlinear simulation
NASA Technical Reports Server (NTRS)
Daniele, C. J.; Krosel, S. M.
1979-01-01
The results and methodology used to derive linear models from a nonlinear simulation are presented. It is shown that averaged positive and negative perturbations in the state variables can reduce numerical errors in finite difference, partial derivative approximations and, in the control inputs, can better approximate the system response in both directions about the operating point. Both explicit and implicit formulations are addressed. Linear models are derived for the F 100 engine, and comparisons of transients are made with the nonlinear simulation. The problem of startup transients in the nonlinear simulation in making these comparisons is addressed. Also, reduction of the linear models is investigated using the modal and normal techniques. Reduced-order models of the F 100 are derived and compared with the full-state models.
Shnitko, Tatiana A; Mace, Kyla D; Sullivan, Kaitlin M; Martin, W Kyle; Andersen, Elizabeth H; Williams Avram, Sarah K; Johns, Josephine M; Robinson, Donita L
2017-12-01
Maternal behavior (MB) is a complex response to infant cues, orchestrated by postpartum neurophysiology. Although mesolimbic dopamine contributes toward MB, little is known about real-time dopamine fluctuations during the postpartum period. Thus, we used fast-scan cyclic voltammetry to measure individual dopamine transients in the nucleus accumbens of early postpartum rats and compared them with dopamine transients in virgins and in postpartum females exposed to cocaine during pregnancy, which is known to disrupt MB. We hypothesized that dopamine transients are normally enhanced postpartum and support MB. In anesthetized rats, electrically evoked dopamine release was larger and clearance was faster in postpartum females than in virgins and gestational cocaine exposure blocked the change in clearance. In awake rats, control mothers showed more dopamine transients than cocaine-exposed mothers during MB. Salient pup-produced stimuli may contribute toward differences in maternal phasic dopamine by evoking dopamine transients; supporting the feasibility of this hypothesis, urine composition (glucose, ketones, and leukocytes) differed between unexposed and cocaine-exposed infants. These data, resulting from the novel application of fast-scan cyclic voltammetry to models of MB, support the hypothesis that phasic dopamine signaling is enhanced postpartum. Future studies with additional controls can delineate which aspects of gestational cocaine reduce dopamine clearance and transient frequency.
Stepwise and Pulse Transient Methods of Thermophysical Parameters Measurement
NASA Astrophysics Data System (ADS)
Malinarič, Svetozár; Dieška, Peter
2016-12-01
Stepwise transient and pulse transient methods are experimental techniques for measuring the thermal diffusivity and conductivity of solid materials. Theoretical models and experimental apparatus are presented, and the influence of the heat source capacity and the heat transfer coefficient is investigated using the experiment simulation. The specimens from low-density polyethylene (LDPE) and polymethylmethacrylate (PMMA) were measured by both methods. Coefficients of variation were better than 0.9 % for LDPE and 2.8 % for PMMA measurements. The time dependence of the temperature response to the input heat flux showed a small drop, which was caused by thermoelastic wave generated by thermal expansions of the heat source.
Investigation of transient cavitating flow in viscoelastic pipes
NASA Astrophysics Data System (ADS)
Keramat, A.; Tijsseling, A. S.; Ahmadi, A.
2010-08-01
A study on water hammer in viscoelastic pipes when the fluid pressure drops to liquid vapour pressure is performed. Two important concepts including column separation and the effects of retarded strains in the pipe wall on the fluid response have been investigated separately in recent works, but there is some curiosity as to how the results for pressure and discharge are when column separation occurs in a viscoelastic pipe. For pipes made of plastic such as polyethylene (PE) and polyvinyl chloride (PVC), viscoelasticity is a crucial mechanical property which changes the hydraulic and structural transient responses. Based on previous developments in the analysis of water hammer, a model which is capable of analysing column separation in viscoelastic pipes is presented and used for solving the selected case studies. For the column-separation modelling the Discrete Vapour Cavity Model (DVCM) is utilised and the viscoelasticity property of the pipe wall is modelled by Kelvin-Voigt elements. The effects of viscoelasticity play an important role in the column separation phenomenon because it changes the water hammer fundamental frequency and so affects the time of opening or collapse of the cavities. Verification of the implemented computer code is performed for the effects of viscoelasticity and column separation - separately and simultaneously - using experimental results from the literature. In the provided examples the focus is placed on the simultaneous effect of viscoelasticity and column separation on the hydraulic transient response. The final conclusions drawn are that if rectangular grids are utilised the DVCM gives acceptable predictions of the phenomenon and that the pipe wall material's retarded behaviour strongly dampens the pressure spikes caused by column separation.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Honrubia-Escribano, A.; Gomez Lazaro, E.; Jimenez-Buendia, F.
The International Electrotechnical Commission Standard 61400-27-1 was published in February 2015. This standard deals with the development of generic terms and parameters to specify the electrical characteristics of wind turbines. Generic models of very complex technological systems, such as wind turbines, are thus defined based on the four common configurations available in the market. Due to its recent publication, the comparison of the response of generic models with specific vendor models plays a key role in ensuring the widespread use of this standard. This paper compares the response of a specific Gamesa dynamic wind turbine model to the corresponding genericmore » IEC Type III wind turbine model response when the wind turbine is subjected to a three-phase voltage dip. This Type III model represents the doubly-fed induction generator wind turbine, which is not only one of the most commonly sold and installed technologies in the current market but also a complex variable-speed operation implementation. In fact, active and reactive power transients are observed due to the voltage reduction. Special attention is given to the reactive power injection provided by the wind turbine models because it is a requirement of current grid codes. Further, the boundaries of the generic models associated with transient events that cannot be represented exactly are included in the paper.« less
Adeeb A. Rahman; Thomas J. Urbanik; Mustafa Mahamid
2006-01-01
This paper presents a model using finite element method to study the response of a typical commercial corrugated fiberboard due to an induced moisture function at one side of the fiberboard. The model predicts how the moisture diffusion will permeate through the fiberboardâs layers(medium and liners) providing information on moisture content at any given point...
NASA Technical Reports Server (NTRS)
Lyle, Karen H.; Vassilakos, Gregory J.
2015-01-01
This report summarizes initial modeling of the local response of the Bigelow Expandable Activity Module (BEAM) to micrometeorite and orbital debris (MMOD) impacts using a structural, non-linear, transient dynamic finite element code. Complementary test results for a local BEAM structure are presented for both hammer and projectile impacts. Review of these data provided guidance for the transient dynamic model development. The local model is intended to support predictions using the global BEAM model, described in a companion report. Two types of local models were developed. One mimics the simplified Soft-Goods (fabric envelop) part of the BEAM NASTRAN model delivered by the project. The second investigates through-the-thickness modeling challenges for MMOD-type impacts. Both the testing and the analysis summaries contain lessons learned and areas for future efforts.
NASA Technical Reports Server (NTRS)
Lovejoy, Andrew E.; Jegley, Dawn C. (Technical Monitor)
2007-01-01
Structures often comprise smaller substructures that are connected to each other or attached to the ground by a set of finite connections. Under static loading one or more of these connections may exceed allowable limits and be deemed to fail. Of particular interest is the structural response when a connection is severed (failed) while the structure is under static load. A transient failure analysis procedure was developed by which it is possible to examine the dynamic effects that result from introducing a discrete failure while a structure is under static load. The failure is introduced by replacing a connection load history by a time-dependent load set that removes the connection load at the time of failure. The subsequent transient response is examined to determine the importance of the dynamic effects by comparing the structural response with the appropriate allowables. Additionally, this procedure utilizes a standard finite element transient analysis that is readily available in most commercial software, permitting the study of dynamic failures without the need to purchase software specifically for this purpose. The procedure is developed and explained, demonstrated on a simple cantilever box example, and finally demonstrated on a real-world example, the American Airlines Flight 587 (AA587) vertical tail plane (VTP).
Topology optimization of finite strain viscoplastic systems under transient loads
Ivarsson, Niklas; Wallin, Mathias; Tortorelli, Daniel
2018-02-08
In this paper, a transient finite strain viscoplastic model is implemented in a gradient-based topology optimization framework to design impact mitigating structures. The model's kinematics relies on the multiplicative split of the deformation gradient, and the constitutive response is based on isotropic hardening viscoplasticity. To solve the mechanical balance laws, the implicit Newmark-beta method is used together with a total Lagrangian finite element formulation. The optimization problem is regularized using a partial differential equation filter and solved using the method of moving asymptotes. Sensitivities required to solve the optimization problem are derived using the adjoint method. To demonstrate the capabilitymore » of the algorithm, several protective systems are designed, in which the absorbed viscoplastic energy is maximized. Finally, the numerical examples demonstrate that transient finite strain viscoplastic effects can successfully be combined with topology optimization.« less
Almquist, Joachim; Bendrioua, Loubna; Adiels, Caroline Beck; Goksör, Mattias; Hohmann, Stefan; Jirstrand, Mats
2015-01-01
The last decade has seen a rapid development of experimental techniques that allow data collection from individual cells. These techniques have enabled the discovery and characterization of variability within a population of genetically identical cells. Nonlinear mixed effects (NLME) modeling is an established framework for studying variability between individuals in a population, frequently used in pharmacokinetics and pharmacodynamics, but its potential for studies of cell-to-cell variability in molecular cell biology is yet to be exploited. Here we take advantage of this novel application of NLME modeling to study cell-to-cell variability in the dynamic behavior of the yeast transcription repressor Mig1. In particular, we investigate a recently discovered phenomenon where Mig1 during a short and transient period exits the nucleus when cells experience a shift from high to intermediate levels of extracellular glucose. A phenomenological model based on ordinary differential equations describing the transient dynamics of nuclear Mig1 is introduced, and according to the NLME methodology the parameters of this model are in turn modeled by a multivariate probability distribution. Using time-lapse microscopy data from nearly 200 cells, we estimate this parameter distribution according to the approach of maximizing the population likelihood. Based on the estimated distribution, parameter values for individual cells are furthermore characterized and the resulting Mig1 dynamics are compared to the single cell times-series data. The proposed NLME framework is also compared to the intuitive but limited standard two-stage (STS) approach. We demonstrate that the latter may overestimate variabilities by up to almost five fold. Finally, Monte Carlo simulations of the inferred population model are used to predict the distribution of key characteristics of the Mig1 transient response. We find that with decreasing levels of post-shift glucose, the transient response of Mig1 tend to be faster, more extended, and displays an increased cell-to-cell variability. PMID:25893847
A comparative analysis of hazard models for predicting debris flows in Madison County, VA
Morrissey, Meghan M.; Wieczorek, Gerald F.; Morgan, Benjamin A.
2001-01-01
During the rainstorm of June 27, 1995, roughly 330-750 mm of rain fell within a sixteen-hour period, initiating floods and over 600 debris flows in a small area (130 km2) of Madison County, Virginia. Field studies showed that the majority (70%) of these debris flows initiated with a thickness of 0.5 to 3.0 m in colluvium on slopes from 17 o to 41 o (Wieczorek et al., 2000). This paper evaluated and compared the approaches of SINMAP, LISA, and Iverson's (2000) transient response model for slope stability analysis by applying each model to the landslide data from Madison County. Of these three stability models, only Iverson's transient response model evaluated stability conditions as a function of time and depth. Iverson?s model would be the preferred method of the three models to evaluate landslide hazards on a regional scale in areas prone to rain-induced landslides as it considers both the transient and spatial response of pore pressure in its calculation of slope stability. The stability calculation used in SINMAP and LISA is similar and utilizes probability distribution functions for certain parameters. Unlike SINMAP that only considers soil cohesion, internal friction angle and rainfall-rate distributions, LISA allows the use of distributed data for all parameters, so it is the preferred model to evaluate slope stability over SINMAP. Results from all three models suggested similar soil and hydrologic properties for triggering the landslides that occurred during the 1995 storm in Madison County, Virginia. The colluvium probably had cohesion of less than 2KPa. The root-soil system is above the failure plane and consequently root strength and tree surcharge had negligible effect on slope stability. The result that the final location of the water table was near the ground surface is supported by the water budget analysis of the rainstorm conducted by Smith et al. (1996).
Lefkoff, L.J.; Gorelick, S.M.
1987-01-01
A FORTRAN-77 computer program code that helps solve a variety of aquifer management problems involving the control of groundwater hydraulics. It is intended for use with any standard mathematical programming package that uses Mathematical Programming System input format. The computer program creates the input files to be used by the optimization program. These files contain all the hydrologic information and management objectives needed to solve the management problem. Used in conjunction with a mathematical programming code, the computer program identifies the pumping or recharge strategy that achieves a user 's management objective while maintaining groundwater hydraulic conditions within desired limits. The objective may be linear or quadratic, and may involve the minimization of pumping and recharge rates or of variable pumping costs. The problem may contain constraints on groundwater heads, gradients, and velocities for a complex, transient hydrologic system. Linear superposition of solutions to the transient, two-dimensional groundwater flow equation is used by the computer program in conjunction with the response matrix optimization method. A unit stress is applied at each decision well and transient responses at all control locations are computed using a modified version of the U.S. Geological Survey two dimensional aquifer simulation model. The program also computes discounted cost coefficients for the objective function and accounts for transient aquifer conditions. (Author 's abstract)
Linkages between ocean circulation, heat uptake and transient warming: a sensitivity study
NASA Astrophysics Data System (ADS)
Pfister, Patrik; Stocker, Thomas
2016-04-01
Transient global warming due to greenhouse gas radiative forcing is substantially reduced by ocean heat uptake (OHU). However, the fraction of equilibrium warming that is realized in transient climate model simulations differs strongly between models (Frölicher and Paynter 2015). It has been shown that this difference is not only related to the magnitude of OHU, but also to the radiative response the OHU causes, measured by the OHU efficacy (Winton et al., 2010). This efficacy is strongly influenced by the spatial pattern of the OHU and its changes (Rose et al. 2014, Winton et al. 2013), predominantly caused by changes in the Atlantic meridional overturning circulation (AMOC). Even in absence of external greenhouse gas forcing, an AMOC weakening causes a radiative imbalance at the top of the atmosphere (Peltier and Vettoretti, 2014), inducing in a net warming of the Earth System. We investigate linkages between those findings by performing both freshwater and greenhouse gas experiments in an Earth System Model of Intermediate Complexity. To assess the sensitivity of the results to ocean and atmospheric transport as well as climate sensitivity, we use an ensemble of model versions, systematically varying key parameters. We analyze circulation changes and radiative adjustments in conjunction with traditional warming metrics such as the transient climate response and the equilibrium climate sensitivity. This aims to improve the understanding of the influence of ocean circulation and OHU on transient climate change, and of the relevance of different metrics for describing this influence. References: Frölicher, T. L. and D.J. Paynter (2015), Extending the relationship between global warming and cumulative carbon emissions to multi-millennial timescales, Environ. Res. Lett., 10, 075022 Peltier, W. R., and G. Vettoretti (2014), Dansgaard-Oeschger oscillations predicted in a comprehensive model of glacial climate: A "kicked" salt oscillator in the Atlantic, Geophys. Res. Lett., 41, 7306-7313 Rose, B. E. J., K. C. Armour, D. S. Battisti, N. Feldl, and D. D. B. Koll (2014), The dependence of transient climate sensitivity and radiative feedbacks on the spatial pattern of ocean heat uptake, Geophys. Res. Lett., 41, 1071-1078 Winton M., K. Takahashi and I. M. Held (2010), Importance of ocean heat uptake efficacy to transient climate change, J. Clim., 23, 2333-44 Winton, M., S. M. Griffies, B. Samuels, J. L. Sarmiento and T. L. Frölicher (2013) Connecting changing ocean circulation with changing climate, J. Clim., 26, 2268-78
Razavi, Payam; Ravicz, Michael E; Dobrev, Ivo; Cheng, Jeffrey Tao; Furlong, Cosme; Rosowski, John J
2016-10-01
The response of the tympanic membrane (TM) to transient environmental sounds and the contributions of different parts of the TM to middle-ear sound transmission were investigated by measuring the TM response to global transients (acoustic clicks) and to local transients (mechanical impulses) applied to the umbo and various locations on the TM. A lightly-fixed human temporal bone was prepared by removing the ear canal, inner ear, and stapes, leaving the incus, malleus, and TM intact. Motion of nearly the entire TM was measured by a digital holography system with a high speed camera at a rate of 42 000 frames per second, giving a temporal resolution of <24 μs for the duration of the TM response. The entire TM responded nearly instantaneously to acoustic transient stimuli, though the peak displacement and decay time constant varied with location. With local mechanical transients, the TM responded first locally at the site of stimulation, and the response spread approximately symmetrically and circumferentially around the umbo and manubrium. Acoustic and mechanical transients provide distinct and complementary stimuli for the study of TM response. Spatial variations in decay and rate of spread of response imply local variations in TM stiffness, mass, and damping. Copyright © 2016 Elsevier B.V. All rights reserved.
Razavi, Payam; Ravicz, Michael E.; Dobrev, Ivo; Cheng, Jeffrey Tao; Furlong, Cosme; Rosowski, John J.
2016-01-01
The response of the tympanic membrane (TM) to transient environmental sounds and the contributions of different parts of the TM to middle-ear sound transmission were investigated by measuring the TM response to global transients (acoustic clicks) and to local transients (mechanical impulses) applied to the umbo and various locations on the TM. A lightly-fixed human temporal bone was prepared by removing the ear canal, inner ear, and stapes, leaving the incus, malleus, and TM intact. Motion of nearly the entire TM was measured by a digital holography system with a high speed camera at a rate of 42 000 frames per second, giving a temporal resolution of <24 μs for the duration of the TM response. The entire TM responded nearly instantaneously to acoustic transient stimuli, though the peak displacement and decay time constant varied with location. With local mechanical transients, the TM responded first locally at the site of stimulation, and the response spread approximately symmetrically and circumferentially around the umbo and manubrium. Acoustic and mechanical transients provide distinct and complementary stimuli for the study of TM response. Spatial variations in decay and rate of spread of response imply local variations in TM stiffness, mass, and damping. PMID:26880098
Transient dynamic analysis of the Bao'An Stadium
NASA Astrophysics Data System (ADS)
Knight, David; Whitefield, Rowan; Nhieu, Eric; Tahmasebinia, Faham; Ansourian, Peter; Alonso-Marroquin, Fernando
2016-08-01
Bao'An Stadium is a unique structure that utilises 54m span cantilevers with tensioned members to support the roof. This report involves a simplified finite element model of Bao'An stadium using Strand7 to analyse the effects of deflections, buckling and earthquake loading. Modelling the cantilevers of the original structure with a double curvature was problematic due to unrealistic deflections and no total mass participation using the Spectral Response Solver. To rectify this, a simplified symmetrical stadium was created and the cable free length attribute was used to induce tension in the inner ring and bottom chord members to create upwards deflection. Further, in place of the Spectral Response Solver, the Transient Linear Dynamic Solver was inputted with an El-Centro earthquake. The stadium's response to a 0.20g earthquake and self-weight indicated the deflections satisfied AS1170.0, the loading in the columns was below the critical buckling load, and all structural members satisfied AS4100.
NASA Technical Reports Server (NTRS)
Ray, Ronald J.
1994-01-01
New flight test maneuvers and analysis techniques for evaluating the dynamic response of in-flight thrust models during throttle transients have been developed and validated. The approach is based on the aircraft and engine performance relationship between thrust and drag. Two flight test maneuvers, a throttle step and a throttle frequency sweep, were developed and used in the study. Graphical analysis techniques, including a frequency domain analysis method, were also developed and evaluated. They provide quantitative and qualitative results. Four thrust calculation methods were used to demonstrate and validate the test technique. Flight test applications on two high-performance aircraft confirmed the test methods as valid and accurate. These maneuvers and analysis techniques were easy to implement and use. Flight test results indicate the analysis techniques can identify the combined effects of model error and instrumentation response limitations on the calculated thrust value. The methods developed in this report provide an accurate approach for evaluating, validating, or comparing thrust calculation methods for dynamic flight applications.
Temporal Treatment of a Thermal Response for Defect Depth Estimation
NASA Technical Reports Server (NTRS)
Plotnikov, Y. A.; Winfree, W. P.
2004-01-01
Transient thermography, which employs pulse surface heating of an inspected component followed by acquisition of the thermal decay stage, is gaining wider acceptance as a result of its remoteness and rapidness. Flaws in the component s material may induce a thermal contrast in surface thermograms. An important issue in transient thermography is estimating the depth of a subsurface flaw from the thermal response. This improves the quantitative ability of the thermal evaluation: from one scan it is possible to locate regions of anomalies in thickness (caused by corrosion) and estimate the implications of the flaw on the integrity of the structure. Our research focuses on thick composite aircraft components. A long square heating pulse and several minutes observation period are required to receive an adequate thermal response from such a component. Application of various time-related informative parameters of the thermal response for depth estimation is discussed. A three-dimensional finite difference model of heat propagation in solids in Cartesian coordinates is used to simulate the thermographic process. Typical physical properties of polymer graphite composites are assumed for the model.
Jackson, Tracie R.; Fenelon, Joseph M.
2018-05-31
This report identifies water-level trends in wells and provides a conceptual framework that explains the hydrologic stresses and factors causing the trends in the Pahute Mesa–Oasis Valley (PMOV) groundwater basin, southern Nevada. Water levels in 79 wells were analyzed for trends between 1966 and 2016. The magnitude and duration of water-level responses to hydrologic stresses were analyzed graphically, statistically, and with water-level models.The conceptual framework consists of multiple stress-specific conceptual models to explain water-level responses to the following hydrologic stresses: recharge, evapotranspiration, pumping, nuclear testing, and wellbore equilibration. Dominant hydrologic stresses affecting water-level trends in each well were used to categorize trends as nonstatic, transient, or steady state.The conceptual framework of water-level responses to hydrologic stresses and trend analyses provide a comprehensive understanding of the PMOV basin and vicinity. The trend analysis links water-level fluctuations in wells to hydrologic stresses and potential factors causing the trends. Transient and steady-state trend categorizations can be used to determine the appropriate water-level data for groundwater studies.
A lumped parameter mathematical model for simulation of subsonic wind tunnels
NASA Technical Reports Server (NTRS)
Krosel, S. M.; Cole, G. L.; Bruton, W. M.; Szuch, J. R.
1986-01-01
Equations for a lumped parameter mathematical model of a subsonic wind tunnel circuit are presented. The equation state variables are internal energy, density, and mass flow rate. The circuit model is structured to allow for integration and analysis of tunnel subsystem models which provide functions such as control of altitude pressure and temperature. Thus the model provides a useful tool for investigating the transient behavior of the tunnel and control requirements. The model was applied to the proposed NASA Lewis Altitude Wind Tunnel (AWT) circuit and included transfer function representations of the tunnel supply/exhaust air and refrigeration subsystems. Both steady state and frequency response data are presented for the circuit model indicating the type of results and accuracy that can be expected from the model. Transient data for closed loop control of the tunnel and its subsystems are also presented, demonstrating the model's use as a control analysis tool.
NASA Technical Reports Server (NTRS)
Wu, R. W.; Witmer, E. A.
1972-01-01
Assumed-displacement versions of the finite-element method are developed to predict large-deformation elastic-plastic transient deformations of structures. Both the conventional and a new improved finite-element variational formulation are derived. These formulations are then developed in detail for straight-beam and curved-beam elements undergoing (1) Bernoulli-Euler-Kirchhoff or (2) Timoshenko deformation behavior, in one plane. For each of these categories, several types of assumed-displacement finite elements are developed, and transient response predictions are compared with available exact solutions for small-deflection, linear-elastic transient responses. The present finite-element predictions for large-deflection elastic-plastic transient responses are evaluated via several beam and ring examples for which experimental measurements of transient strains and large transient deformations and independent finite-difference predictions are available.
Naito, M; Fuchikami, N; Sasaki, N; Kambara, T
1991-01-01
The dynamic response of the lipid bilayer membrane is studied theoretically using a microscopic model of the membrane. The time courses of membrane potential variations due to monovalent salt stimulation are calculated explicitly under various conditions. A set of equations describing the time evolution of membrane surface potential and diffusion potential is derived and solved numerically. It is shown that a rather simple membrane such as lipid bilayer has functions capable of reproducing the following properties of dynamic response observed in gustatory receptor potential. Initial transient depolarization does not occur under Ringer adaptation but does under water. It appears only for comparatively rapid flows of stimuli, the peak height of transient response is expressed by a power function of the flow rate, and the membrane potential gradually decreases after reaching its peak under long and strong stimulation. The dynamic responses in the present model arise from the differences between the time dependences in the surface potential phi s and the diffusion potential phi d across a membrane. Under salt stimulation phi d cannot immediately follow the variation in phi s because of the delay due to the charging up of membrane capacitance. It is suggested that lipid bilayer in the apical membrane is the most probable agency producing the initial phasic response to the stimulation. PMID:1873461
Analysis of shell type structures subjected to time dependent mechanical and thermal loading
NASA Technical Reports Server (NTRS)
Simitses, G. J.; Carlson, R. L.; Riff, R.
1985-01-01
A general mathematical model and solution methodologies for analyzing structural response of thin, metallic shell-type structures under large transient, cyclic or static thermomechanical loads is considered. Among the system responses, which are associated with these load conditions, are thermal buckling, creep buckling and ratchetting. Thus, geometric as well as material-type nonlinearities (of high order) can be anticipated and must be considered in the development of the mathematical model.
Effects of nearshore recharge on groundwater interactions with a lake in mantled karst terrain
Lee, Terrie M.
2000-01-01
The recharge and discharge of groundwater were investigated for a lake basin in the mantled karst terrain of central Florida to determine the relative importance of transient groundwater inflow to the lake water budget. Variably saturated groundwater flow modeling simulated water table responses observed beneath two hillsides radiating outward from the groundwater flow‐through lake. Modeling results indicated that transient water table mounding and groundwater flow reversals in the nearshore region following large daily rainfall events generated most of the net groundwater inflow to the lake. Simulated daily groundwater inflow was greatest following water table mounding near the lake, not following subsequent peaks in the water level of upper basin wells. Transient mounding generated net groundwater inflow to the lake, that is, groundwater inflow in excess of the outflow occurring through the deeper lake bottom. The timing of the modeled net groundwater inflow agreed with an independent lake water budget; however, the quantity was considerably less than the budget‐derived value.
Evaluating transient performance of servo mechanisms by analysing stator current of PMSM
NASA Astrophysics Data System (ADS)
Zhang, Qing; Tan, Luyao; Xu, Guanghua
2018-02-01
Smooth running and rapid response are the desired performance goals for the transient motions of servo mechanisms. Because of the uncertain and unobservable transient behaviour of servo mechanisms, it is difficult to evaluate their transient performance. Under the effects of electromechanical coupling, the stator current signals of a permanent-magnet synchronous motor (PMSM) potentially contain the performance information regarding servo mechanisms in use. In this paper, a novel method based on analysing the stator current of the PMSM is proposed for quantifying the transient performance. First, a vector control model is constructed to simulate the stator current behaviour in the transient processes of consecutive speed changes, consecutive load changes, and intermittent start-stops. It is discovered that the amplitude and frequency of the stator current are modulated by the transient load torque and motor speed, respectively. The stator currents under different performance conditions are also simulated and compared. Then, the stator current is processed using a local means decomposition (LMD) algorithm to extract the instantaneous amplitude and instantaneous frequency. The sample entropy of the instantaneous amplitude, which reflects the complexity of the load torque variation, is calculated as a performance indicator of smooth running. The peak-to-peak value of the instantaneous frequency, which defines the range of the motor speed variation, is set as a performance indicator of rapid response. The proposed method is applied to both simulated data in an intermittent start-stops process and experimental data measured for a batch of servo turrets for turning lathes. The results show that the performance evaluations agree with the actual performance.
Earth system responses to cumulative carbon emissions
NASA Astrophysics Data System (ADS)
Steinacher, M.; Joos, F.
2015-07-01
Information on the relationship between cumulative fossil carbon emissions and multiple climate targets are essential to design emission mitigation and climate adaptation strategies. In this study, the transient responses in different climate variables are quantified for a large set of multi-forcing scenarios extended to year 2300 towards stabilization and in idealized experiments using the Bern3D-LPJ carbon-climate model. The model outcomes are constrained by 26 physical and biogeochemical observational data sets in a Bayesian, Monte-Carlo type framework. Cumulative fossil emissions of 1000 Gt C result in a global mean surface air temperature change of 1.88 °C (68 % confidence interval (c.i.): 1.28 to 2.69 °C), a decrease in surface ocean pH of 0.19 (0.18 to 0.22), and in steric sea level rise of 20 cm (13 to 27 cm until 2300). Linearity between cumulative emissions and transient response is high for pH and reasonably high for surface air and sea surface temperatures, but less pronounced for changes in Atlantic Meridional Overturning, Southern Ocean and tropical surface water saturation with respect to biogenic structures of calcium carbonate, and carbon stocks in soils. The slopes of the relationships change when CO2 is stabilized. The Transient Climate Response is constrained, primarily by long-term ocean heat observations, to 1.7 °C (68 % c.i.: 1.3 to 2.2 °C) and the Equilibrium Climate Sensitivity to 2.9 °C (2.0 to 4.2 °C). This is consistent with results by CMIP5 models, but inconsistent with recent studies that relied on short-term air temperature data affected by natural climate variability.
Ay, Hakan; Arsava, E Murat; Johnston, S Claiborne; Vangel, Mark; Schwamm, Lee H; Furie, Karen L; Koroshetz, Walter J; Sorensen, A Gregory
2009-01-01
Predictive instruments based on clinical features for early stroke risk after transient ischemic attack suffer from limited specificity. We sought to combine imaging and clinical features to improve predictions for 7-day stroke risk after transient ischemic attack. We studied 601 consecutive patients with transient ischemic attack who had MRI within 24 hours of symptom onset. A logistic regression model was developed using stroke within 7 days as the response criterion and diffusion-weighted imaging findings and dichotomized ABCD(2) score (ABCD(2) >/=4) as covariates. Subsequent stroke occurred in 25 patients (5.2%). Dichotomized ABCD(2) score and acute infarct on diffusion-weighted imaging were each independent predictors of stroke risk. The 7-day risk was 0.0% with no predictor, 2.0% with ABCD(2) score >/=4 alone, 4.9% with acute infarct on diffusion-weighted imaging alone, and 14.9% with both predictors (an automated calculator is available at http://cip.martinos.org). Adding imaging increased the area under the receiver operating characteristic curve from 0.66 (95% CI, 0.57 to 0.76) using the ABCD(2) score to 0.81 (95% CI, 0.74 to 0.88; P=0.003). The sensitivity of 80% on the receiver operating characteristic curve corresponded to a specificity of 73% for the CIP model and 47% for the ABCD(2) score. Combining acute imaging findings with clinical transient ischemic attack features causes a dramatic boost in the accuracy of predictions with clinical features alone for early risk of stroke after transient ischemic attack. If validated in relevant clinical settings, risk stratification by the CIP model may assist in early implementation of therapeutic measures and effective use of hospital resources.
Lifetime Reliability Prediction of Ceramic Structures Under Transient Thermomechanical Loads
NASA Technical Reports Server (NTRS)
Nemeth, Noel N.; Jadaan, Osama J.; Gyekenyesi, John P.
2005-01-01
An analytical methodology is developed to predict the probability of survival (reliability) of ceramic components subjected to harsh thermomechanical loads that can vary with time (transient reliability analysis). This capability enables more accurate prediction of ceramic component integrity against fracture in situations such as turbine startup and shutdown, operational vibrations, atmospheric reentry, or other rapid heating or cooling situations (thermal shock). The transient reliability analysis methodology developed herein incorporates the following features: fast-fracture transient analysis (reliability analysis without slow crack growth, SCG); transient analysis with SCG (reliability analysis with time-dependent damage due to SCG); a computationally efficient algorithm to compute the reliability for components subjected to repeated transient loading (block loading); cyclic fatigue modeling using a combined SCG and Walker fatigue law; proof testing for transient loads; and Weibull and fatigue parameters that are allowed to vary with temperature or time. Component-to-component variation in strength (stochastic strength response) is accounted for with the Weibull distribution, and either the principle of independent action or the Batdorf theory is used to predict the effect of multiaxial stresses on reliability. The reliability analysis can be performed either as a function of the component surface (for surface-distributed flaws) or component volume (for volume-distributed flaws). The transient reliability analysis capability has been added to the NASA CARES/ Life (Ceramic Analysis and Reliability Evaluation of Structures/Life) code. CARES/Life was also updated to interface with commercially available finite element analysis software, such as ANSYS, when used to model the effects of transient load histories. Examples are provided to demonstrate the features of the methodology as implemented in the CARES/Life program.
Transient Thermal Testing and Analysis of a Thermally Insulating Structural Sandwich Panel
NASA Technical Reports Server (NTRS)
Blosser, Max L.; Daryabeigi, Kamran; Bird, Richard K.; Knutson, Jeffrey R.
2015-01-01
A core configuration was devised for a thermally insulating structural sandwich panel. Two titanium prototype panels were constructed to illustrate the proposed sandwich panel geometry. The core of one of the titanium panels was filled with Saffil(trademark) alumina fibrous insulation and the panel was tested in a series of transient thermal tests. Finite element analysis was used to predict the thermal response of the panel using one- and two-dimensional models. Excellent agreement was obtained between predicted and measured temperature histories.
NASA Astrophysics Data System (ADS)
Suzuki, Masato; Nagata, Kazuma; Tanushi, Yuichiro; Yokoyama, Shin
2007-04-01
We have fabricated Mach-Zhender interferometers (MZIs) using the (Ba,Sr)TiO3 (BST) film sputter-deposited at 450 °C, which is a critical temperature for the process after metallization. An optical modulation of about 10% is achieved when 200 V is applied (electric field in BST is 1.2× 104 V/cm). However, the response time of optical modulation to step function voltage is slow (1.0-6.3 s). We propose a model for the slow transient behavior based on movable ions and a long dielectric relaxation time for the BST film, and good qualitative agreement is obtained with experimental results.
Baum, Rex L.; Godt, Jonathan W.; Savage, William Z.
2010-01-01
Shallow rainfall-induced landslides commonly occur under conditions of transient infiltration into initially unsaturated soils. In an effort to predict the timing and location of such landslides, we developed a model of the infiltration process using a two-layer system that consists of an unsaturated zone above a saturated zone and implemented this model in a geographic information system (GIS) framework. The model links analytical solutions for transient, unsaturated, vertical infiltration above the water table to pressure-diffusion solutions for pressure changes below the water table. The solutions are coupled through a transient water table that rises as water accumulates at the base of the unsaturated zone. This scheme, though limited to simplified soil-water characteristics and moist initial conditions, greatly improves computational efficiency over numerical models in spatially distributed modeling applications. Pore pressures computed by these coupled models are subsequently used in one-dimensional slope-stability computations to estimate the timing and locations of slope failures. Applied over a digital landscape near Seattle, Washington, for an hourly rainfall history known to trigger shallow landslides, the model computes a factor of safety for each grid cell at any time during a rainstorm. The unsaturated layer attenuates and delays the rainfall-induced pore-pressure response of the model at depth, consistent with observations at an instrumented hillside near Edmonds, Washington. This attenuation results in realistic estimates of timing for the onset of slope instability (7 h earlier than observed landslides, on average). By considering the spatial distribution of physical properties, the model predicts the primary source areas of landslides.
Time-domain approach for the transient responses in stratified viscoelastic Earth models
NASA Technical Reports Server (NTRS)
Hanyk, L.; Moser, J.; Yuen, D. A.; Matyska, C.
1995-01-01
We have developed the numerical algorithm for the computation of transient viscoelastic responses in the time domain for a radially stratified Earth model. Stratifications in both the elastic parameters and the viscosity profile have been considered. The particular viscosity profile employed has a viscosity maximum with a constrast of O(100) in the mid lower mantle. The distribution of relaxation times reveals the presence of a continuous spectrum situated between O(100) and O(exp 4) years. The principal mode is embedded within this continuous spectrum. From this initial-value approach we have found that for the low degree harmonics the non-modal contributions are comparable to the modal contributions. For this viscosity model the differences between the time-domain and normal-mode results are found to decrease strongly with increasing angular order. These calculations also show that a time-dependent effective relaxation time can be defined, which can be bounded by the relaxation times of the principal modes.
Ribbon synapses compute temporal contrast and encode luminance in retinal rod bipolar cells
Oesch, Nicholas W.; Diamond, Jeffrey S.
2011-01-01
Contrast is computed throughout the nervous system to encode changing inputs efficiently. The retina encodes luminance and contrast over a wide range of visual conditions and so must adapt its responses to maintain sensitivity and avoid saturation. Here we show how one type of adaptation allows individual synapses to compute contrast and encode luminance in biphasic responses to step changes in light levels. Light-evoked depletion of the readily releasable vesicle pool (RRP) at rod bipolar cell (RBC) ribbon synapses in rat retina limits the dynamic range available to encode transient but not sustained responses, thereby allowing the transient and sustained components of release to compute temporal contrast and encode mean light levels, respectively. A release/replenishment model shows that a single, homogeneous pool of synaptic vesicles is sufficient to generate this behavior and reveals that the dominant mechanism shaping the biphasic contrast/luminance response is the partial depletion of the RRP. PMID:22019730
Transient Region Coverage in the Propulsion IVHM Technology Experiment
NASA Technical Reports Server (NTRS)
Balaban, Edward; Sweet, Adam; Bajwa, Anupa; Maul, William; Fulton, Chris; Chicatelli, amy
2004-01-01
Over the last several years researchers at NASA Glenn and Ames Research Centers have developed a real-time fault detection and isolation system for propulsion subsystems of future space vehicles. The Propulsion IVHM Technology Experiment (PITEX), as it is called follows the model-based diagnostic methodology and employs Livingstone, developed at NASA Ames, as its reasoning engine. The system has been tested on,flight-like hardware through a series of nominal and fault scenarios. These scenarios have been developed using a highly detailed simulation of the X-34 flight demonstrator main propulsion system and include realistic failures involving valves, regulators, microswitches, and sensors. This paper focuses on one of the recent research and development efforts under PITEX - to provide more complete transient region coverage. It describes the development of the transient monitors, the corresponding modeling methodology, and the interface software responsible for coordinating the flow of information between the quantitative monitors and the qualitative, discrete representation Livingstone.
NASA Technical Reports Server (NTRS)
Gallardo, V. C.; Storace, A. S.; Gaffney, E. F.; Bach, L. J.; Stallone, M. J.
1981-01-01
The component element method was used to develop a transient dynamic analysis computer program which is essentially based on modal synthesis combined with a central, finite difference, numerical integration scheme. The methodology leads to a modular or building-block technique that is amenable to computer programming. To verify the analytical method, turbine engine transient response analysis (TETRA), was applied to two blade-out test vehicles that had been previously instrumented and tested. Comparison of the time dependent test data with those predicted by TETRA led to recommendations for refinement or extension of the analytical method to improve its accuracy and overcome its shortcomings. The development of working equations, their discretization, numerical solution scheme, the modular concept of engine modelling, the program logical structure and some illustrated results are discussed. The blade-loss test vehicles (rig full engine), the type of measured data, and the engine structural model are described.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ivarsson, Niklas; Wallin, Mathias; Tortorelli, Daniel
In this paper, a transient finite strain viscoplastic model is implemented in a gradient-based topology optimization framework to design impact mitigating structures. The model's kinematics relies on the multiplicative split of the deformation gradient, and the constitutive response is based on isotropic hardening viscoplasticity. To solve the mechanical balance laws, the implicit Newmark-beta method is used together with a total Lagrangian finite element formulation. The optimization problem is regularized using a partial differential equation filter and solved using the method of moving asymptotes. Sensitivities required to solve the optimization problem are derived using the adjoint method. To demonstrate the capabilitymore » of the algorithm, several protective systems are designed, in which the absorbed viscoplastic energy is maximized. Finally, the numerical examples demonstrate that transient finite strain viscoplastic effects can successfully be combined with topology optimization.« less
Ivarsson, Niklas; Wallin, Mathias; Tortorelli, Daniel
2018-02-08
In this paper, a transient finite strain viscoplastic model is implemented in a gradient-based topology optimization framework to design impact mitigating structures. The model's kinematics relies on the multiplicative split of the deformation gradient, and the constitutive response is based on isotropic hardening viscoplasticity. To solve the mechanical balance laws, the implicit Newmark-beta method is used together with a total Lagrangian finite element formulation. The optimization problem is regularized using a partial differential equation filter and solved using the method of moving asymptotes. Sensitivities required to solve the optimization problem are derived using the adjoint method. To demonstrate the capabilitymore » of the algorithm, several protective systems are designed, in which the absorbed viscoplastic energy is maximized. Finally, the numerical examples demonstrate that transient finite strain viscoplastic effects can successfully be combined with topology optimization.« less
NASA Astrophysics Data System (ADS)
Jost, A.; Violette, S.; Gonçalvès, J.; Ledoux, E.; Guyomard, Y.; Guillocheau, F.; Kageyama, M.; Ramstein, G.; Suc, J.-P.
In the framework of safe underground storage of radioactive waste in low-permeability layers, it is essential to evaluate the mobility of deep groundwaters over timescales of several million years. On these timescales, the environmental evolution of a repository should depend upon a range of natural processes that are primarily driven by climate and geomorphologic variations. In this paper, the response of the Paris basin groundwater system to variations in its hydrodynamic boundary conditions induced by past climate and geodynamic changes over the last five million years is investigated. A three-dimensional transient modelling of the Paris basin aquifer/aquitard system was developed using the code NEWSAM (Ecole des Mines de Paris, ENSMP). The geometry and hydrodynamic parameters of the model originate from a basin model, NEWBAS (ENSMP), built to simulate the geological history of the basin. Geomorphologic evolution is deduced from digital elevation model analysis, which allows to estimate river-valley incision and alpine surrection. Climate forcing results from palaeoclimate modelling experiments using the LMDz atmospheric general circulation model (Institut Pierre Simon Laplace) with a refined spatial resolution, for the present, the Last Glacial Maximum (21 ka) and the Middle Pliocene Warmth (˜3 Ma). The water balance is computed by the distributed hydrological model MODSUR (ENSMP). Results about the simulated evolution of piezometric heads in the system in response to the altered boundary conditions are presented, in particular in the vicinity of ANDRA’s Bure potential repository site within the Callovo-Oxfordian argillaceous layer. For the present, the comparison of head patterns between steady state and time dependent simulation shows little differences for aquifer layers close to the surface but suggests a transient state of the current system in the main aquitards of the basin and in the deep aquifers, characterized by abnormally low fluid potentials. The dependence of the boundary-induced transient effects on the hydraulic diffusivity is illustrated by means of a sensitivity study.
Modeling static and dynamic human cardiovascular responses to exercise.
Stremel, R W; Bernauer, E M; Harter, L W; Schultz, R A; Walters, R F
1975-08-01
A human performance model has been developed and described [9] which portrays the human circulatory, thermo regulatory and energy-exchange systems as an intercoupled set. In this model, steady state or static relationships are used to describe oxygen consumption and blood flow. For example, heart rate (HTRT) is calculated as a function of the oxygen and the thermo-regulatory requirements of each body compartment, using the steady state work values of cardiac output (CO, sum of all compartment blood flows) and stroke volume (SV, assumed maximal after 40% maximal oxygen consumption): HTRT=CO/SV. The steady state model has proven to be an acceptable first approximation, but the inclusion of transient characteristics are essential in describing the overall systems' adjustment to exercise stress. In the present study, the dynamic transient characteristics of heart rate, stroke volume and cardiac output were obtained from experiments utilizing step and sinusoidal forcing of work. The gain and phase relationships reveal a probable first order system with a six minute time constant, and are utilized to model the transient characteristics of these parameters. This approach leads to a more complex model but a more accurate representation of the physiology involved. The instrumentation and programming essential to these experiments are described.
Efficient Charge Collection in Coplanar-Grid Radiation Detectors
NASA Astrophysics Data System (ADS)
Kunc, J.; Praus, P.; Belas, E.; Dědič, V.; Pekárek, J.; Grill, R.
2018-05-01
We model laser-induced transient-current waveforms in radiation coplanar-grid detectors. Poisson's equation is solved by the finite-element method and currents induced by a photogenerated charge are obtained using the Shockley-Ramo theorem. The spectral response on a radiation flux is modeled by Monte Carlo simulations. We show a 10 × improved spectral resolution of the coplanar-grid detector using differential signal sensing. We model the current waveform dependence on the doping, depletion width, diffusion, and detector shielding, and their mutual dependence is discussed in terms of detector optimization. The numerical simulations are successfully compared to experimental data, and further model simplifications are proposed. The space charge below electrodes and a nonhomogeneous electric field on a coplanar-grid anode are found to be the dominant contributions to laser-induced transient-current waveforms.
Short-term depression and transient memory in sensory cortex.
Gillary, Grant; Heydt, Rüdiger von der; Niebur, Ernst
2017-12-01
Persistent neuronal activity is usually studied in the context of short-term memory localized in central cortical areas. Recent studies show that early sensory areas also can have persistent representations of stimuli which emerge quickly (over tens of milliseconds) and decay slowly (over seconds). Traditional positive feedback models cannot explain sensory persistence for at least two reasons: (i) They show attractor dynamics, with transient perturbations resulting in a quasi-permanent change of system state, whereas sensory systems return to the original state after a transient. (ii) As we show, those positive feedback models which decay to baseline lose their persistence when their recurrent connections are subject to short-term depression, a common property of excitatory connections in early sensory areas. Dual time constant network behavior has also been implemented by nonlinear afferents producing a large transient input followed by much smaller steady state input. We show that such networks require unphysiologically large onset transients to produce the rise and decay observed in sensory areas. Our study explores how memory and persistence can be implemented in another model class, derivative feedback networks. We show that these networks can operate with two vastly different time courses, changing their state quickly when new information is coming in but retaining it for a long time, and that these capabilities are robust to short-term depression. Specifically, derivative feedback networks with short-term depression that acts differentially on positive and negative feedback projections are capable of dynamically changing their time constant, thus allowing fast onset and slow decay of responses without requiring unrealistically large input transients.
Modeling Fluvial Incision and Transient Landscape Evolution: Influence of Dynamic Channel Adjustment
NASA Astrophysics Data System (ADS)
Attal, M.; Tucker, G. E.; Cowie, P. A.; Whittaker, A. C.; Roberts, G. P.
2007-12-01
Channel geometry exerts a fundamental control on fluvial processes. Recent work has shown that bedrock channel width (W) depends on a number of parameters, including channel slope, and is not only a function of drainage area (A) as is commonly assumed. The present work represents the first attempt to investigate the consequences, for landscape evolution, of using a static expression of channel width (W ~ A0.5) versus a relationship that allows channels to dynamically adjust to changes in slope. We consider different models for the evolution of the channel geometry, including constant width-to-depth ratio (after Finnegan et al., Geology, v. 33, no. 3, 2005), and width-to-depth ratio varying as a function of slope (after Whittaker et al., Geology, v. 35, no. 2, 2007). We use the Channel-Hillslope Integrated Landscape Development (CHILD) model to analyze the response of a catchment to a given tectonic disturbance. The topography of a catchment in the footwall of an active normal fault in the Apennines (Italy) is used as a template for the study. We show that, for this catchment, the transient response can be fairly well reproduced using a simple detachment-limited fluvial incision law. We also show that, depending on the relationship used to express channel width, initial steady-state topographies differ, as do transient channel width, slope, and the response time of the fluvial system. These differences lead to contrasting landscape morphologies when integrated at the scale of a whole catchment. Our results emphasize the importance of channel width in controlling fluvial processes and landscape evolution. They stress the need for using a dynamic hydraulic scaling law when modeling landscape evolution, particularly when the uplift field is non-uniform.
Coupled wave model for large magnet coils
NASA Technical Reports Server (NTRS)
Gabriel, G. J.
1980-01-01
A wave coupled model based on field theory is evolved for analysis of fast electromagnetic transients on superconducting coils. It is expected to play a useful role in the design of protection methods against damage due to high voltages or any adverse effects that might arise from unintentional transients. The significant parameters of the coil are identified to be the turn to turn wave coupling coefficients and the travel time of an electromagnetic disturbance around a single turn. Unlike circuit theoretic inductor, the coil response evolves in discrete steps having durations equal to this travel time. It is during such intervals that high voltages are likely to occur. The model also bridges the gap between the low and high ends of the frequency spectrum.
West, Robert; Braver, Todd
2009-01-01
Current theories are divided as to whether prospective memory (PM) involves primarily sustained processes such as strategic monitoring, or transient processes such as the retrieval of intentions from memory when a relevant cue is encountered. The current study examined the neural correlates of PM using a functional magnetic resonance imaging design that allows for the decomposition of brain activity into sustained and transient components. Performance of the PM task was primarily associated with sustained responses in a network including anterior prefrontal cortex (lateral Brodmann area 10), and these responses were dissociable from sustained responses associated with active maintenance in working memory. Additionally, the sustained responses in anterior prefrontal cortex correlated with faster response times for prospective responses. Prospective cues also elicited selective transient activity in a region of interest along the right middle temporal gyrus. The results support the conclusion that both sustained and transient processes contribute to efficient PM and provide novel constraints on the functional role of anterior PFC in higher-order cognition. PMID:18854581
Ehrensberger, Mark T; Gilbert, Jeremy L
2010-05-01
The measurement of electrochemical impedance is a valuable tool to assess the electrochemical environment that exists at the surface of metallic biomaterials. This article describes the development and validation of a new technique, potential step impedance analysis (PSIA), to assess the electrochemical impedance of materials whose interface with solution can be modeled as a simplified Randles circuit that is modified with a constant phase element. PSIA is based upon applying a step change in voltage to a working electrode and analyzing the subsequent current transient response in a combined time and frequency domain technique. The solution resistance, polarization resistance, and interfacial capacitance are found directly in the time domain. The experimental current transient is numerically transformed to the frequency domain to determine the constant phase exponent, alpha. This combined time and frequency approach was tested using current transients generated from computer simulations, from resistor-capacitor breadboard circuits, and from commercially pure titanium samples immersed in phosphate buffered saline and polarized at -800 mV or +1000 mV versus Ag/AgCl. It was shown that PSIA calculates equivalent admittance and impedance behavior over this range of potentials when compared to standard electrochemical impedance spectroscopy. This current transient approach characterizes the frequency response of the system without the need for expensive frequency response analyzers or software. Copyright 2009 Wiley Periodicals, Inc.
Dynamic Fluid in a Porous Transducer-Based Angular Accelerometer
Cheng, Siyuan; Fu, Mengyin; Wang, Meiling; Ming, Li; Fu, Huijin; Wang, Tonglei
2017-01-01
This paper presents a theoretical model of the dynamics of liquid flow in an angular accelerometer comprising a porous transducer in a circular tube of liquid. Wave speed and dynamic permeability of the transducer are considered to describe the relation between angular acceleration and the differential pressure on the transducer. The permeability and streaming potential coupling coefficient of the transducer are determined in the experiments, and special prototypes are utilized to validate the theoretical model in both the frequency and time domains. The model is applied to analyze the influence of structural parameters on the frequency response and the transient response of the fluidic system. It is shown that the radius of the circular tube and the wave speed affect the low frequency gain, as well as the bandwidth of the sensor. The hydrodynamic resistance of the transducer and the cross-section radius of the circular tube can be used to control the transient performance. The proposed model provides the basic techniques to achieve the optimization of the angular accelerometer together with the methodology to control the wave speed and the hydrodynamic resistance of the transducer. PMID:28230793
NASA Technical Reports Server (NTRS)
Brown, Andrew M.; Schmauch, Preston
2012-01-01
Turbine blades in rocket and jet engine turbomachinery experience enormous harmonic loading conditions. These loads result from the integer number of upstream and downstream stator vanes as well as the other turbine stages. Assessing the blade structural integrity is a complex task requiring an initial characterization of whether resonance is possible and then performing a forced response analysis if that condition is met. The standard technique for forced response analysis in rocket engine turbines is to decompose a computational fluid dynamics (CFD).generated flow field into its harmonic components, and to then perform a frequency response analysis at the problematic natural frequencies using cyclically symmetric structural dynamic models. Recent CFD analysis and water-flow testing at NASA/MSFC, though, indicates that this technique may miss substantial harmonic and non ]harmonic excitation sources that become present in complex flows. This complex content can only be captured by a CFD flow field encompassing at least an entire revolution. A substantial development effort to create a series of software programs to enable application of the 360 degree forcing function in a frequency response analysis on cyclic symmetric models has been completed (to be described in a future paper), but the question still remains whether the frequency response analysis itself is capable of capturing the excitation content sufficiently. Two studies comparing frequency response analysis with transient response analysis, therefore, of bladed-disks undergoing this complex flow environment have been performed. The first is of a bladed disk with each blade modeled by simple beam elements and the disk modeled with plates (using the finite element code MSC/NASTRAN). The focus of this model is to be representative of response of realistic bladed disks, and so the dimensions are roughly equivalent to the new J2X rocket engine 1st stage fuel pump turbine. The simplicity of the model allows the CFD load to be able to be readily applied, along with analytical and experimental variations in both the temporal and spatial fourier components of the excitation. In addition, this model is a first step in identifying response differences between transient and frequency forced response analysis techniques. The second phase assesses this difference for a much more realistic solid model of a bladed-disk in order to evaluate the effect of the spatial variation in loading on blade dominated modes. Neither research on the accuracy of the frequency response method when used in this context or a comprehensive study of the effect of test-observed variation on blade forced response have been found in the literature, so this research is a new contribution to practical structural dynamic analysis of gas turbines. The primary excitation of the upstream nozzles interacts with the blades on fuel pump of the J2X causes the 5th Nodal diameter modes to be excited, as explained by Tyler and Sofrin1, so a modal analysis was first performed on the beam/plate model and the 5ND bladed-disk mode at 40167 hz was identified and chosen to be the one excited at resonance (see figure 1). The first forced response analysis with this model focuses on identifying differences between frequency and transient response analyses. A hypothesis going into the analysis was that perhaps the frequency response was enforcing a temporal periodicity that did not really exist, and so therefore it would overestimate the response. As high dynamic response was a considerable source of stress in the J2X, examining this concept could potentially be beneficial for the program.
Dynamic analysis of solid propellant grains subjected to ignition pressurization loading
NASA Astrophysics Data System (ADS)
Chyuan, Shiang-Woei
2003-11-01
Traditionally, the transient analysis of solid propellant grains subjected to ignition pressurization loading was not considered, and quasi-elastic-static analysis was widely adopted for structural integrity because the analytical task gets simplified. But it does not mean that the dynamic effect is not useful and could be neglected arbitrarily, and this effect usually plays a very important role for some critical design. In order to simulate the dynamic response for solid rocket motor, a transient finite element model, accompanied by concepts of time-temperature shift principle, reduced integration and thermorheologically simple material assumption, was used. For studying the dynamic response, diverse ignition pressurization loading cases were used and investigated in the present paper. Results show that the dynamic effect is important for structural integrity of solid propellant grains under ignition pressurization loading. Comparing the effective stress of transient analysis and of quasi-elastic-static analysis, one can see that there is an obvious difference between them because of the dynamic effect. From the work of quasi-elastic-static and transient analyses, the dynamic analysis highlighted several areas of interest and a more accurate and reasonable result could be obtained for the engineer.
Heavy Ion Microbeam- and Broadbeam-Induced Current Transients in SiGe HBTs
NASA Technical Reports Server (NTRS)
Pellish, Jonathan A.; Reed, R. A.; McMorrow, D.; Vizkelethy, G.; Ferlet-Cavrois, V.; Baggio, J.; Duhamel, O.; Moen, K. A.; Phillips, S. D.; Diestelhorst, R. M.;
2009-01-01
IBM 5AM SiGe HBT is device-under-test. High-speed measurement setup. Low-impedance current transient measurements. SNL, JYFL, GANIL. Microbeam to broadbeam position inference. Improvement to state-of-the-art. Microbeam (SNL) transients reveal position dependent heavy ion response, Unique response for different device regions Unique response for different bias schemes. Similarities to TPA pulsed-laser data. Broadbeam transients (JYFL and GANIL) provide realistic heavy ion response. Feedback using microbeam data. Overcome issues of LET and ion range with microbeam. **Angled Ar-40 data in full paper. Data sets yield first-order results, suitable for TCAD calibration feedback.
Satir, Sarp; Zahorian, Jaime; Degertekin, F. Levent
2014-01-01
A large signal, transient model has been developed to predict the output characteristics of a CMUT array operated in the non-collapse mode. The model is based on separation of the nonlinear electrostatic voltage-to-force relation and the linear acoustic array response. For linear acoustic radiation and crosstalk effects, the boundary element method is used. The stiffness matrix in the vibroacoustics calculations is obtained using static finite element analysis of a single membrane which can have arbitrary geometry and boundary conditions. A lumped modeling approach is used to reduce the order of the system for modeling the transient nonlinear electrostatic actuation. To accurately capture the dynamics of the non-uniform electrostatic force distribution over the CMUT electrode during large deflections, the membrane electrode is divided into patches shaped to match higher order membrane modes, each introducing a variable to the system model. This reduced order nonlinear lumped model is solved in the time domain using Simulink. The model has two linear blocks to calculate the displacement profile of the electrode patches and the output pressure for a given force distribution over the array, respectively. The force to array displacement block uses the linear acoustic model, and the Rayleigh integral is evaluated to calculate the pressure at any field point. Using the model, the transient transmitted pressure can be simulated for different large signal drive signal configurations. The acoustic model is verified by comparison to harmonic FEA in vacuum and fluid for high and low aspect ratio membranes as well as mass-loaded membranes. The overall Simulink model is verified by comparison to transient 3D FEA and experimental results for different large drive signals; and an example for a phased array simulation is given. PMID:24158297
Sensing the heat stress by Mammalian cells.
Cates, Jordan; Graham, Garrett C; Omattage, Natalie; Pavesich, Elizabeth; Setliff, Ian; Shaw, Jack; Smith, Caitlin Lee; Lipan, Ovidiu
2011-08-11
The heat-shock response network controls the adaptation and survival of the cell against environmental stress. This network is highly conserved and is connected with many other signaling pathways. A key element of the heat-shock network is the heat-shock transcription factor-1 (HSF), which is transiently activated by elevated temperatures. HSF translocates to the nucleus upon elevated temperatures, forming homotrimeric complexes. The HSF homotrimers bind to the heat shock element on the DNA and control the expression of the hsp70 gene. The Hsp70 proteins protect cells from thermal stress. Thermal stress causes the unfolding of proteins, perturbing thus the pathways under their control. By binding to these proteins, Hsp70 allows them to refold and prevents their aggregation. The modulation of the activity of the hsp70-promoter by the intensity of the input stress is thus critical for cell's survival. The promoter activity starts from a basal level and rapidly increases once the stress is applied, reaches a maximum level and attenuates slowely back to the basal level. This phenomenon is the hallmark of many experimental studies and of all computational network analysis. The molecular construct used as a measure of the response to thermal stress is a Hsp70-GFP fusion gene transfected in Chinese hamster ovary (CHO) cells. The time profile of the GFP protein depends on the transient activity, Transient(t), of the heat shock system. The function Transient(t) depends on hsp70 promoter activity, transcriptional regulation and the translation initiation effects elicited by the heat stress. The GFP time profile is recorded using flow cytometry measurements, a technique that allows a quantitative measurement of the fluorescence of a large number of cells (104). The GFP responses to one and two heat shocks were measured for 261 conditions of different temperatures and durations. We found that: (i) the response of the cell to two consecutive shocks (i.e., no recovery time in between shocks) depends on the order of the input shocks, that is the shocks do not commute; (ii) the responses may be classified as mild or severe, depending on the temperature level and the duration of the heat shock and (iii) the response is highly sensitive to small variations in temperature. We propose a mathematical model that maps temperature into the transient activity using experimental data that describes the time course of the response to input thermal stress. The model is built on thermotolerance without recovery time, sharp sensitivity to small variations in temperature and the existence of mild and severe classes of stress responses. The theoretical predictions are tested against experimental data using a series of double-shock inputs. The theoretical structure is represented by a sequence of three cascade processes that transform the input stress into the transient activity. The structure of the cascade is nonlinear-linear-nonlinear (NLN). The first nonlinear system (N) from the NLN structure represents the amplification of small changes in the environmental temperature; the linear system (L) represents the thermotolerance without recovery time, whereas the last system (N) represents the transition of the cell's response from a mild to a severe shock.
Negroni, Jorge A.; Morotti, Stefano; Lascano, Elena C.; Gomes, Aldrin V.; Grandi, Eleonora; Puglisi, José L; Bers, Donald M.
2015-01-01
A five-state model of myofilament contraction was integrated into a well-established rabbit ventricular myocyte model of ion channels, Ca2+ transporters and kinase signaling to analyze the relative contribution of different phosphorylation targets to the overall mechanical response driven by β-adrenergic stimulation (β-AS). β-AS effect on sarcoplasmic reticulum Ca2+ handling, Ca2+, K+ and Cl− currents, and Na+/K+-ATPase properties were included based on experimental data. The inotropic effect on the myofilaments was represented as reduced myofilament Ca2+ sensitivity (XBCa) and titin stiffness, and increased cross-bridge (XB) cycling rate (XBcy). Assuming independent roles of XBCa and XBcy, the model reproduced experimental β-AS responses on action potentials and Ca2+ transient amplitude and kinetics. It also replicated the behavior of force-Ca2+, release-restretch, length-step, stiffness-frequency and force-velocity relationships, and increased force and shortening in isometric and isotonic twitch contractions. The β-AS effect was then switched off from individual targets to analyze their relative impact on contractility. Preventing β-AS effects on L-type Ca2+ channels or phospholamban limited Ca2+ transients and contractile responses in parallel, while blocking phospholemman and K+ channel (IKs) effects enhanced Ca2+ and inotropy. Removal of β-AS effects from XBCa enhanced contractile force while decreasing peak Ca2+ (due to greater Ca2+ buffering), but had less effect on shortening. Conversely, preventing β-AS effects on XBcy preserved Ca2+ transient effects, but blunted inotropy (both isometric force and especially shortening). Removal of titin effects had little impact on contraction. Finally, exclusion of β-AS from XBCa and XBcy while preserving effects on other targets resulted in preserved peak isometric force response (with slower kinetics) but nearly abolished enhanced shortening. β-AS effects on XBCa vs. XBcy have greater impact on isometric vs. isotonic contraction, respectively. PMID:25724724
Transient Creep of a Composite Lower Crust. 1; Constitutive Theory
NASA Technical Reports Server (NTRS)
Ivins, Erik R.; Sammis, Charles G.
1996-01-01
A composite model is proposed to describe the time-dependent response of the Earth's lower crust. The motivation for such it model is twofold: First, new observations of widespread postseismic deformation indicate that the deep continental crust responds viscoelastically, having both long-and short-term decay times. Second, by any number of observationally based rationales, the lower crust is compositionally and structurally heterogeneous over many length scales. For heterogeneities that have much smaller characteristic lengths than the minimum deformation wavelength of interest, the aggregate rheology can be described by composite media theory. For wavelengths of the order of the thickness of the lower crust (approx. = 25-40 km) and larger, composite theory may be applied to heterogeneities that are smaller than about several hundred meters, or equivalent to the vertical extent of a thick lower crustal mylonitic shear zone. The composite media theory developed here is constructed using both Eshelhy-Mori-Tanaka theory for aligned generalized spheroidal inclusions and a generalized self-consistent method. The inclusions and matrix are considered to be Maxwellian viscoelastic: a rheology that is consistent with past homogeneous models of postseismic stress relaxation. The composite theory presented here introduces a transient response to a suddenly imposed stress field which does not appear in homogeneous Maxwell models. Analytic expressions for the amplitude and duration of the transient and for the effective long-and short-term viscosities of the composite are given which describe the sensitivity to inclusion concentration (phi), to shape, and to ratio of inclusion-to-matrix viscosity (R).
NASA Astrophysics Data System (ADS)
Eakins, D. E.; Thadhani, N. N.
2006-10-01
Instrumented Taylor anvil-on-rod impact tests have been conducted on oxygen-free electronic copper to validate the accuracy of current strength models for predicting transient states during dynamic deformation events. The experiments coupled the use of high-speed digital photography to record the transient deformation states and laser interferometry to monitor the sample back (free surface) velocity as a measure of the elastic/plastic wave propagation through the sample length. Numerical continuum dynamics simulations of the impact and plastic wave propagation employing the Johnson-Cook [Proceedings of the Seventh International Symposium on Ballistics, 1983, The Netherlands (Am. Def. Prep. Assoc. (ADPA)), pp. 541-547], Zerilli-Armstrong [J. Appl. Phys. C1, 1816 (1987)], and Steinberg-Guinan [J. Appl. Phys. 51, 1498 (1980)] constitutive equations were used to generate transient deformation profiles and the free surface velocity traces. While these simulations showed good correlation with the measured free surface velocity traces and the final deformed sample shape, varying degrees of deviations were observed between the photographed and calculated specimen profiles at intermediate deformation states. The results illustrate the usefulness of the instrumented Taylor anvil-on-rod impact technique for validating constitutive equations that can describe the path-dependent deformation response and can therefore predict the transient and final deformation states.
NASA Astrophysics Data System (ADS)
Heinrich, S. M.; Wenzel, M. J.; Josse, F.; Dufour, I.
2009-06-01
The problem governing the transient deformation of an elastic cantilever beam with viscoelastic coating, subjected to a time-dependent coating eigenstrain, is mathematically formulated. An analytical solution for an exponential eigenstrain history, exact within the context of beam theory, is obtained in terms of the coating and base layer thicknesses, the elastic modulus of the base material, the initial coating modulus, the coating relaxation percentage (0%-100%), and the time constants of the coating's relaxation process and its eigenstrain history. Approximate formulas, valid for thin coatings, are derived as special cases to provide insight into system behavior. Main results include (1) the time histories of the beam curvature and the coating stresses, (2) a criterion governing the response type (monotonic or "overshoot" response), and (3) simple expressions for the overshoot ratio, defined as the peak response scaled by the steady-state response, and the time at which the peak response occurs. Applications to polymer-coated microcantilever-based chemical sensors operating in the static mode are discussed.
NASA Astrophysics Data System (ADS)
Seo, H.; Kwon, Y. O.; Joyce, T. M.
2016-02-01
A remarkably strong nonlinear behavior of the atmospheric circulation response to North Atlantic SST anomalies (SSTA) is revealed from a set of large-ensemble, high-resolution, and hemispheric-scale Weather Research and Forecasting (WRF) model simulations. The model is forced with the SSTA associated with meridional shift of the Gulf Stream (GS) path, constructed from a lag regression of the winter SST on a GS Index from observation. Analysis of the systematic set of experiments with SSTAs of varied amplitudes and switched signs representing various GS-shift scenarios provides unique insights into mechanism for emergence and evolution of transient and equilibrium response of atmospheric circulation to extratropical SSTA. Results show that, independent of sign of the SSTA, the equilibrium response is characterized by an anomalous trough over the North Atlantic Ocean and the Western Europe concurrent with enhanced storm track, increased rainfall, and reduced blocking days. To the north of the anomalous low, an anomalous ridge emerges over the Greenland, Iceland, and Norwegian Seas accompanied by weakened storm track, reduced rainfall and increased blocking days. This nonlinear component of the total response dominates the weak and oppositely signed linear response that is directly forced by the SSTA, yielding an anomalous ridge (trough) downstream of the warm (cold) SSTA. The amplitude of the linear response is proportional to that of the SSTA, but this is masked by the overwhelmingly strong nonlinear behavior showing no clear correspondence to the SSTA amplitude. The nonlinear pattern emerges 3-4 weeks after the model initialization in November and reaches its first peak amplitude in December/January. It appears that altered baroclinic wave activity due to the GS SSTA in November lead to low-frequency height responses in December/January through transient eddy vorticity flux convergence.
Pupillary transient responses to within-task cognitive load variation.
Wong, Hoe Kin; Epps, Julien
2016-12-01
Changes in physiological signals due to task evoked cognitive load have been reported extensively. However, pupil size based approaches for estimating cognitive load on a moment-to-moment basis are not as well understood as estimating cognitive load on a task-to-task basis, despite the appeal these approaches have for continuous load estimation. In particular, the pupillary transient response to instantaneous changes in induced load has not been experimentally quantified, and the within-task changes in pupil dilation have not been investigated in a manner that allows their consistency to be quantified with a view to biomedical system design. In this paper, a variation of the digit span task is developed which reliably induces rapid changes of cognitive load to generate task-evoked pupillary responses (TEPRs) associated with large, within-task load changes. Linear modelling and one-way ANOVA reveals that increasing the rate of cognitive loading, while keeping task demands constant, results in a steeper pupillary response. Instantaneous drops in cognitive load are shown to produce statistically significantly different transient pupillary responses relative to sustained load, and when characterised using an exponential decay response, the task-evoked pupillary response time constant is in the order of 1-5 s. Within-task test-retest analysis confirms the reliability of the moment-to-moment measurements. Based on these results, estimates of pupil diameter can be employed with considerably more confidence in moment-to-moment cognitive load estimation systems. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
Sustained and transient attention in the continuous performance task.
Smid, H G O M; de Witte, M R; Homminga, I; van den Bosch, R J
2006-08-01
One of the most frequently applied methods to study abnormal cognition is the Continuous Performance Task (CPT). It is unclear, however, which cognitive functions are engaged in normal CPT performance. The aims of the present study were to identify the neurocognitive functions engaged in the main variants of the CPT and to determine to what extent these variants differentially engage these functions. We hypothesized that the main CPT versions (CPT-X, CPT-AX, CPT-Identical Pairs) can be distinguished by whether they demand sustained or transient attention and sustained or transient response preparation. Transient attention to objects like letters or digits, that is, the need to switch attention to different objects from trial to trial, impairs target detection accuracy relative to sustained attention to a single object. Transient response preparation, that is, the possibility to switch response preparation on and off from trial to trial, improves response speed relative to having to sustain response preparation across all trials. Comparison of task performance and Event-Related brain Potentials (ERPs) of healthy participants obtained in the main CPT variants confirmed these hypotheses. Behavioral and ERP measures indicated worse target detection in the CPT-AX than in the CPT-X, consistent with a higher demand on transient attention in that task. In contrast, behavioral and ERP measures indicated higher response speed in the CPT-AX than in the CPT-X, associated with more response preparation in advance of the targets. This supports the idea of increased transient response preparation in the CPT-AX. We conclude that CPTs differ along at least two task variables that each influences a different cognitive function.
NASA Astrophysics Data System (ADS)
Fu, Chao; Ren, Xingmin; Yang, Yongfeng; Xia, Yebao; Deng, Wangqun
2018-07-01
A non-intrusive interval precise integration method (IPIM) is proposed in this paper to analyze the transient unbalance response of uncertain rotor systems. The transfer matrix method (TMM) is used to derive the deterministic equations of motion of a hollow-shaft overhung rotor. The uncertain transient dynamic problem is solved by combing the Chebyshev approximation theory with the modified precise integration method (PIM). Transient response bounds are calculated by interval arithmetic of the expansion coefficients. Theoretical error analysis of the proposed method is provided briefly, and its accuracy is further validated by comparing with the scanning method in simulations. Numerical results show that the IPIM can keep good accuracy in vibration prediction of the start-up transient process. Furthermore, the proposed method can also provide theoretical guidance to other transient dynamic mechanical systems with uncertainties.
Transient response in granular bounded heap flows
NASA Astrophysics Data System (ADS)
Xiao, Hongyi; Ottino, Julio M.; Lueptow, Richard M.; Umbanhowar, Paul B.
2017-11-01
Heap formation, a canonical granular flow, is common in industry and is also found in nature. Here, we study the transition between steady flow states in quasi-2D bounded heaps by suddenly changing the feed rate from one fixed value to another. During the transition, in both experiments and discrete element method simulations, an additional wedge of flowing particles propagates over the rising free surface. The downstream edge of the wedge - the wedge front - moves downstream with velocity inversely proportional to the square root of time. An additional longer duration transient process continues after the wedge front reaches the downstream wall. The transient flux profile during the entire transition is well modeled by a diffusion-like equation derived from local mass balance and a local linear relation between the flux and the surface slope. Scalings for the transient kinematics during the flow transitions are developed based on the flux profiles. Funded by NSF Grant CBET-1511450.
Pearce, Timothy C.; Karout, Salah; Rácz, Zoltán; Capurro, Alberto; Gardner, Julian W.; Cole, Marina
2012-01-01
We present a biologically-constrained neuromorphic spiking model of the insect antennal lobe macroglomerular complex that encodes concentration ratios of chemical components existing within a blend, implemented using a set of programmable logic neuronal modeling cores. Depending upon the level of inhibition and symmetry in its inhibitory connections, the model exhibits two dynamical regimes: fixed point attractor (winner-takes-all type), and limit cycle attractor (winnerless competition type) dynamics. We show that, when driven by chemosensor input in real-time, the dynamical trajectories of the model's projection neuron population activity accurately encode the concentration ratios of binary odor mixtures in both dynamical regimes. By deploying spike timing-dependent plasticity in a subset of the synapses in the model, we demonstrate that a Hebbian-like associative learning rule is able to organize weights into a stable configuration after exposure to a randomized training set comprising a variety of input ratios. Examining the resulting local interneuron weights in the model shows that each inhibitory neuron competes to represent possible ratios across the population, forming a ratiometric representation via mutual inhibition. After training the resulting dynamical trajectories of the projection neuron population activity show amplification and better separation in their response to inputs of different ratios. Finally, we demonstrate that by using limit cycle attractor dynamics, it is possible to recover and classify blend ratio information from the early transient phases of chemosensor responses in real-time more rapidly and accurately compared to a nearest-neighbor classifier applied to the normalized chemosensor data. Our results demonstrate the potential of biologically-constrained neuromorphic spiking models in achieving rapid and efficient classification of early phase chemosensor array transients with execution times well beyond biological timescales. PMID:23874265
Focused cognitive control in dishonesty: Evidence for predominantly transient conflict adaptation.
Foerster, Anna; Pfister, Roland; Schmidts, Constantin; Dignath, David; Wirth, Robert; Kunde, Wilfried
2018-04-01
Giving a dishonest response to a question entails cognitive conflict due to an initial activation of the truthful response. Following conflict monitoring theory, dishonest responding could therefore elicit transient and sustained control adaptation processes to mitigate such conflict, and the current experiments take on the scope and specificity of such conflict adaptation in dishonesty. Transient adaptation reduces differences between honest and dishonest responding following a recent dishonest response. Sustained adaptation has a similar behavioral signature but is driven by the overall frequency of dishonest responding. Both types of adaptation to recent and frequent dishonest responses have been separately documented, leaving open whether control processes in dishonest responding can flexibly adapt to transient and sustained conflict signals of dishonest and other actions. This was the goal of the present experiments which studied (dis)honest responding to autobiographical yes/no questions. Experiment 1 showed robust transient adaptation to recent dishonest responses whereas sustained control adaptation failed to exert an influence on behavior. It further revealed that transient effects may create a spurious impression of sustained adaptation in typical experimental settings. Experiments 2 and 3 examined whether dishonest responding can profit from transient and sustained adaption processes triggered by other behavioral conflicts. This was clearly not the case: Dishonest responding adapted markedly to recent (dis)honest responses but not to any context of other conflicts. These findings indicate that control adaptation in dishonest responding is strong but surprisingly focused and they point to a potential trade-off between transient and sustained adaptation. (PsycINFO Database Record (c) 2018 APA, all rights reserved).
Low-Dimensional Model of a Cylinder Wake
NASA Astrophysics Data System (ADS)
Luchtenburg, Mark; Cohen, Kelly; Siegel, Stefan; McLaughlin, Tom
2003-11-01
In a two-dimensional cylinder wake, self-excited oscillations in the form of periodic shedding of vortices are observed above a critical Reynolds number of about 47. These flow-induced non-linear oscillations lead to some undesirable effects associated with unsteady pressures such as fluid-structure interactions. An effective way of suppressing the self-excited flow oscillations is by the incorporation of closed-loop flow control. In this effort, a low dimensional, proper orthogonal decomposition (POD) model is based on data obtained from direct numerical simulations of the Navier Stokes equations for the two dimensional circular cylinder wake at a Reynolds number of 100. Three different conditions are examined, namely, the unforced wake experiencing steady-state vortex shedding, the transient behavior of the unforced wake at the startup of the simulation, and transient response to open-loop harmonic forcing by translation. We discuss POD mode selection and the number of modes that need to be included in the low-dimensional model. It is found that the transient dynamics need to be represented by a coupled system that includes an aperiodic mean-flow mode, an aperiodic shift mode and the periodic von Karman modes. Finally, a least squares mapping method is introduced to develop the non-linear state equations. The predictive capability of the state equations demonstrates the ability of the above approach to model the transient dynamics of the wake.
Godt, J.W.; Baum, R.L.; Savage, W.Z.; Salciarini, D.; Schulz, W.H.; Harp, E.L.
2008-01-01
Application of transient deterministic shallow landslide models over broad regions for hazard and susceptibility assessments requires information on rainfall, topography and the distribution and properties of hillside materials. We survey techniques for generating the spatial and temporal input data for such models and present an example using a transient deterministic model that combines an analytic solution to assess the pore-pressure response to rainfall infiltration with an infinite-slope stability calculation. Pore-pressures and factors of safety are computed on a cell-by-cell basis and can be displayed or manipulated in a grid-based GIS. Input data are high-resolution (1.8??m) topographic information derived from LiDAR data and simple descriptions of initial pore-pressure distribution and boundary conditions for a study area north of Seattle, Washington. Rainfall information is taken from a previously defined empirical rainfall intensity-duration threshold and material strength and hydraulic properties were measured both in the field and laboratory. Results are tested by comparison with a shallow landslide inventory. Comparison of results with those from static infinite-slope stability analyses assuming fixed water-table heights shows that the spatial prediction of shallow landslide susceptibility is improved using the transient analyses; moreover, results can be depicted in terms of the rainfall intensity and duration known to trigger shallow landslides in the study area.
NASA Astrophysics Data System (ADS)
Mailen, Russell W.; Dickey, Michael D.; Genzer, Jan; Zikry, Mohammed
2017-11-01
Shape memory polymer (SMP) sheets patterned with black ink hinges change shape in response to external stimuli, such as absorbed thermal energy from an infrared (IR) light. The geometry of these hinges, including size, orientation, and location, and the applied thermal loads significantly influence the final folded shape of the sheet, but these variables have not been fully investigated. We perform a systematic study on SMP sheets to fundamentally understand the effects of single and double hinge geometries, hinge orientation and spacing, initial temperature, heat flux intensity, and pattern width on the folding behavior. We have developed thermo-viscoelastic finite element models to characterize and quantify the stresses, strains, and temperatures as they relate to SMP shape changes. Our predictions indicate that hinge orientation can be used to reduce the total bending angle, which is the angle traversed by the folding face of the sheet. Two parallel hinges increase the total bending angle, and heat conduction between the hinges affects the transient folding response. IR intensity and initial temperatures can also influence the transient folding behavior. These results can provide guidelines to optimize the transient folding response and the three-dimensional folded structure obtained from self-folding polymer origami sheets that can be applied for myriad applications.
Transient Performance of a Vertical Axis Wind Turbine
NASA Astrophysics Data System (ADS)
Onol, Aykut; Yesilyurt, Serhat
2016-11-01
A coupled CFD/rotor dynamics modeling approach is presented for the analysis of realistic transient behavior of a height-normalized, three-straight-bladed VAWT subject to inertial effects of the rotor and generator load which is manipulated by a feedback control under standardized wind gusts. The model employs the k- ɛ turbulence model to approximate unsteady Reynolds-averaged Navier-Stokes equations and is validated with data from field measurements. As distinct from related studies, here, the angular velocity is calculated from the rotor's equation of motion; thus, the dynamic response of the rotor is taken into account. Results include the following: First, the rotor's inertia filters large amplitude oscillations in the wind torque owing to the first-order dynamics. Second, the generator and wind torques differ especially during wind transients subject to the conservation of angular momentum of the rotor. Third, oscillations of the power coefficient exceed the Betz limit temporarily due to the energy storage in the rotor, which acts as a temporary buffer that stores the kinetic energy like a flywheel in short durations. Last, average of transient power coefficients peaks at a smaller tip-speed ratio for wind gusts than steady winds. This work was supported by the Sabanci University Internal Research Grant Program (SU-IRG-985).
DOE Office of Scientific and Technical Information (OSTI.GOV)
Feltus, M.A.
1987-01-01
Analysis results for multiple steam generator blow down caused by an auxiliary feedwater steam-line break performed with the RETRAN-02 MOD 003 computer code are presented to demonstrate the capabilities of the RETRAN code to predict system transient response for verifying changes in operational procedures and supporting plant equipment modifications. A typical four-loop Westinghouse pressurized water reactor was modeled using best-estimate versus worst case licensing assumptions. This paper presents analyses performed to evaluate the necessity of implementing an auxiliary feedwater steam-line isolation modification. RETRAN transient analysis can be used to determine core cooling capability response, departure from nucleate boiling ratio (DNBR)more » status, and reactor trip signal actuation times.« less
Linear simulation of the stationary eddies in a GCM. II - The 'Mountain' model
NASA Technical Reports Server (NTRS)
Nigam, Sumant; Held, Isaac M.; Lyons, Steven W.
1988-01-01
Linear stationary wave theory is used to account for zonal asymmetries of the winter-averaged tropospheric circulation obtained in a GCM. The eddy zonal velocity field in the upper troposphere indicates that the orographic and thermal plus transient contributions are nearly equal in amplitude, while the eddy meridional velocity field (which is dominated by shorter zonal scales) shows the orographic contribution to be dominant. The two contributions are found to be roughly in phase over the east Asian coast, and they contribute roughly equal amounts to the low level Siberian high. Results indicate that the 300 mb extratropical response to tropical forcing reaches 50 gpm over Alaska, and that the responses to sensible heating and lower tropospheric transients are strongly anticorrelated.
Renewable source controls for grid stability.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Byrne, Raymond Harry; Elliott, Ryan Thomas; Neely, Jason C.
2012-12-01
The goal of this study was to evaluate the small signal and transient stability of the Western Electric- ity Coordinating Council (WECC) under high penetrations of renewable energy, and to identify control technologies that would improve the system performance. The WECC is the regional entity responsible for coordinating and promoting bulk electric system reliability in the Western Interconnection. Transient stability is the ability of the power system to maintain synchronism after a large disturbance while small signal stability is the ability of the power system to maintain synchronism after a small disturbance. Tran- sient stability analysis usually focuses on themore » relative rotor angle between synchronous machines compared to some stability margin. For this study we employed generator speed relative to system speed as a metric for assessing transient stability. In addition, we evaluated the system transient response using the system frequency nadir, which provides an assessment of the adequacy of the primary frequency control reserves. Small signal stability analysis typically identi es the eigenvalues or modes of the system in response to a disturbance. For this study we developed mode shape maps for the di erent scenarios. Prony analysis was applied to generator speed after a 1.4 GW, 0.5 second, brake insertion at various locations. Six di erent WECC base cases were analyzed, including the 2022 light spring case which meets the renewable portfolio standards. Because of the di culty in identifying the cause and e ect relationship in large power system models with di erent scenarios, several simulations were run on a 7-bus, 5-generator system to isolate the e ects of di erent con gurations. Based on the results of the study, for a large power system like the WECC, incorporating frequency droop into wind/solar systems provides a larger bene t to system transient response than replacing the lost inertia with synthetic inertia. From a small signal stability perspective, the increase in renewable penetration results in subtle changes to the system modes. In gen- eral, mode frequencies increase slightly, and mode shapes remain similar. The system frequency nadir for the 2022 light spring case was slightly lower than the other cases, largely because of the reduced system inertia. However, the nadir is still well above the minimum load shedding frequency of 59.5 Hz. Finally, several discrepancies were identi ed between actual and reported wind penetration, and additional work on wind/solar modeling is required to increase the delity of the WECC models.« less
Blade loss transient dynamics analysis with flexible bladed disk
NASA Technical Reports Server (NTRS)
Gallardo, V. C.; Black, G.; Bach, L.; Cline, S.; Storace, A.
1983-01-01
The transient dynamic response of a flexible bladed disk on a flexible rotor in a two rotor system is formulated by modal synthesis and a Lagrangian approach. Only the nonequilibrated one diameter flexible mode is considered for the flexible bladed disk, while the two flexible rotors are represented by their normal modes. The flexible bladed disk motion is modeled as a combination of two one diameter standing waves, and is coupled inertially and gyroscopically to the flexible rotors. Application to a two rotor model shows that a flexible bladed disk on one rotor can be driven into resonance by an unbalance in the other rotor, and at a frequency equal to the difference in the rotor speeds.
Scott W. Bailey; Patricia A. Brousseau; Kevin J. McGuire; Donald S. Ross
2014-01-01
Upland headwater catchments, such as those in the AppalachianMountain region, are typified by coarse textured soils, flashy hydrologic response, and low baseflow of streams, suggesting well drained soils and minimal groundwater storage. Model formulations of soil genesis, nutrient cycling, critical loads and rainfall/runoff response are typically based on vertical...
NASA Technical Reports Server (NTRS)
Key, Samuel W.
1993-01-01
The explicit transient dynamics technology in use today for simulating the impact and subsequent transient dynamic response of a structure has its origins in the 'hydrocodes' dating back to the late 1940's. The growth in capability in explicit transient dynamics technology parallels the growth in speed and size of digital computers. Computer software for simulating the explicit transient dynamic response of a structure is characterized by algorithms that use a large number of small steps. In explicit transient dynamics software there is a significant emphasis on speed and simplicity. The finite element technology used to generate the spatial discretization of a structure is based on a compromise between completeness of the representation for the physical processes modelled and speed in execution. That is, since it is expected in every calculation that the deformation will be finite and the material will be strained beyond the elastic range, the geometry and the associated gradient operators must be reconstructed, as well as complex stress-strain models evaluated at every time step. As a result, finite elements derived for explicit transient dynamics software use the simplest and barest constructions possible for computational efficiency while retaining an essential representation of the physical behavior. The best example of this technology is the four-node bending quadrilateral derived by Belytschko, Lin and Tsay. Today, the speed, memory capacity and availability of computer hardware allows a number of the previously used algorithms to be 'improved.' That is, it is possible with today's computing hardware to modify many of the standard algorithms to improve their representation of the physical process at the expense of added complexity and computational effort. The purpose is to review a number of these algorithms and identify the improvements possible. In many instances, both the older, faster version of the algorithm and the improved and somewhat slower version of the algorithm are found implemented together in software. Specifically, the following seven algorithmic items are examined: the invariant time derivatives of stress used in material models expressed in rate form; incremental objectivity and strain used in the numerical integration of the material models; the use of one-point element integration versus mean quadrature; shell elements used to represent the behavior of thin structural components; beam elements based on stress-resultant plasticity versus cross-section integration; the fidelity of elastic-plastic material models in their representation of ductile metals; and the use of Courant subcycling to reduce computational effort.
NASA Astrophysics Data System (ADS)
Ghosh, A.; Majumder, S. B.
2017-07-01
Iso-butane (i-C4H10) is one of the major components of liquefied petroleum gas which is used as fuel in domestic and industrial applications. Developing chemi-resistive selective i-C4H10 thin film sensors remains a major challenge. Two strategies were undertaken to differentiate carbon monoxide, hydrogen, and iso-butane gases from the measured conductance transients of cobalt doped zinc oxide thin films. Following the first strategy, the response and recovery transients of conductances in these gas environments are fitted using the Langmuir adsorption kinetic model to estimate the heat of adsorption, response time constant, and activation energies for adsorption (response) and desorption (recovery). Although these test gases have seemingly different vapor densities, molecular diameters, and reactivities, analyzing the estimated heat of adsorption and activation energies (for both adsorption and desorption), we could not differentiate these gases unequivocally. However, we have found that the lower the vapor density, the faster the response time irrespective of the test gas concentration. As a second strategy, we demonstrated that feature extraction of conductance transients (using fast Fourier transformation) in conjunction with the pattern recognition algorithm (principal component analysis) is more fruitful to address the cross-sensitivity of Co doped ZnO thin film sensors. We have found that although the dispersion among different concentrations of hydrogen and carbon monoxide could not be avoided, each of these three gases forms distinct clusters in the plot of principal component 2 versus 1 and therefore could easily be differentiated.
NASA Astrophysics Data System (ADS)
Kimura, T.; Hiraki, Y.; Tao, C.; Tsuchiya, F.; Delamere, P. A.; Yoshioka, K.; Murakami, G.; Yamazaki, A.; Kita, H.; Badman, S. V.; Fukazawa, K.; Yoshikawa, I.; Fujimoto, M.
2018-03-01
The production and transport of plasma mass are essential processes in the dynamics of planetary magnetospheres. At Jupiter, it is hypothesized that Io's volcanic plasma carried out of the plasma torus is transported radially outward in the rotating magnetosphere and is recurrently ejected as plasmoid via tail reconnection. The plasmoid ejection is likely associated with particle energization, radial plasma flow, and transient auroral emissions. However, it has not been demonstrated that plasmoid ejection is sensitive to mass loading because of the lack of simultaneous observations of both processes. We report the response of plasmoid ejection to mass loading during large volcanic eruptions at Io in 2015. Response of the transient aurora to the mass loading rate was investigated based on a combination of Hisaki satellite monitoring and a newly developed analytic model. We found that the transient aurora frequently recurred at a 2-6 day period in response to a mass loading increase from 0.3 to 0.5 t/s. In general, the recurrence of the transient aurora was not significantly correlated with the solar wind, although there was an exceptional event with a maximum emission power of 10 TW after the solar wind shock arrival. The recurrence of plasmoid ejection requires the precondition that an amount comparable to the total mass of magnetosphere, 1.5 Mt, is accumulated in the magnetosphere. A plasmoid mass of more than 0.1 Mt is necessary in case that the plasmoid ejection is the only process for mass release.
Analysis of shell-type structures subjected to time-dependent mechanical and thermal loading
NASA Technical Reports Server (NTRS)
Simitses, G. J.; Riff, R.
1987-01-01
A general mathematical model and solution methodologies for analyzing structural response of thin, metallic shell-type structures under large transient, cyclic, or static thermomechanical loads are developed. Among the system responses, which are associated with these load conditions, are thermal buckling, creep buckling and ratcheting. Thus, geometric as well as material type nonlinearities (of high order) can be anticipated and must be considered in the development of the mathematical model. Furthermore, this must also be accommodated in the solution procedures.
Analysis of shell-type structures subjected to time-dependent mechanical and thermal loading
NASA Technical Reports Server (NTRS)
Simitses, G. J.; Carlson, R. L.; Riff, R.
1987-01-01
A general mathematical model and solution methodologies are being developed for analyzing structural response of thin, metallic shell-type structures under large transient, cyclic, or static thermomechanical loads. Among the system responses, which were associated with these load conditions, were thermal buckling, creep buckling, and ratcheting. Thus, geometric as well as material-type nonlinearities (of high order) can be anticipated and must be considered in the development of the mathematical model. Furthermore, this must also be accommodated in the solution process.
Unraveling the Age Hardening Response in U-Nb Alloys
Hackenberg, Robert Errol; Hemphill, Geralyn M. Sewald; Forsyth, Robert Thomas; ...
2016-11-15
Complicating factors that have stymied understanding of uranium-niobium’s aging response are briefly reviewed, including (1) niobium inhomogeneity, (2) machining damage effects on tensile properties, (3) early-time transients of ductility increase, and (4) the variety of phase transformations. A simple Logistic-Arrhenius model was applied to predict yield and ultimate tensile strengths and tensile elongation of U-4Nb as a function of thermal age. Lastly, fits to each model yielded an apparent activation energy that was compared with phase transformation mechanisms.
USDA-ARS?s Scientific Manuscript database
In this paper we proposed: (1) an algorithm of glacier melt, sublimation/evaporation, accumulation, mass balance and retreat; (2) a dynamic Hydrological Response Unit approach for incorporating the algorithm into the Soil and Water Assessment Tool (SWAT) model; and (3) simulated the transient glacie...
Cone-shaped source characteristics and inductance effect of transient electromagnetic method
NASA Astrophysics Data System (ADS)
Yang, Hai-Yan; Li, Feng-Ping; Yue, Jian-Hua; Guo, Fu-Sheng; Liu, Xu-Hua; Zhang, Hua
2017-03-01
Small multi-turn coil devices are used with the transient electromagnetic method (TEM) in areas with limited space, particularly in underground environments such as coal mines roadways and engineering tunnels, and for detecting shallow geological targets in environmental and engineering fields. However, the equipment involved has strong mutual inductance coupling, which causes a lengthy turn-offtime and a deep "blind zone". This study proposes a new transmitter device with a conical-shape source and derives the radius formula of each coil and the mutual inductance coefficient of the cone. According to primary field characteristics, results of the two fields created, calculation of the conical-shaped source in a uniform medium using theoretical analysis, and a comparison of the inductance of the new device with that of the multi-turn coil, show that inductance of the multi-turn coil is nine times greater than that of the conical source with the same equivalent magnetic moment of 926.1 A·m2. This indicates that the new source leads to a much shallower "blind zone." Furthermore, increasing the bottom radius and turn of the cone creates a larger mutual inductance but increasing the cone height results in a lower mutual inductance. Using the superposition principle, the primary and secondary magnetic fields for a conical source in a homogeneous medium are calculated; results indicate that the magnetic behavior of the cone is the same as that of the multi-turn coils, but the transient responses of the secondary field and the total field are more stronger than those of the multi-turn coils. To study the transient response characteristics using a cone-shaped source in a layered earth, a numerical filtering algorithm is then developed using the fast Hankel transform and the improved cosine transform, again using the superposition principle. During development, an average apparent resistivity inverted from the induced electromotive force using each coil is defined to represent the comprehensive resistivity of the conical source. To verify the forward calculation method, the transient responses of H type models and KH type models are calculated, and data are inverted using a "smoke ring" inversion. The results of inversion have good agreement with original models and show that the forward calculation method is effective. The results of this study provide an option for solving the problem of a deep "blind zone" and also provide a theoretical indicator for further research.
Climate variability and vadose zone controls on damping of transient recharge
Corona, Claudia R.; Gurdak, Jason J.; Dickinson, Jesse; Ferré, T.P.A.; Maurer, Edwin P.
2018-01-01
Increasing demand on groundwater resources motivates understanding of the controls on recharge dynamics so model predictions under current and future climate may improve. Here we address questions about the nonlinear behavior of flux variability in the vadose zone that may explain previously reported teleconnections between global-scale climate variability and fluctuations in groundwater levels. We use hundreds of HYDRUS-1D simulations in a sensitivity analysis approach to evaluate the damping depth of transient recharge over a range of periodic boundary conditions and vadose zone geometries and hydraulic parameters that are representative of aquifer systems of the conterminous United States (U.S). Although the models were parameterized based on U.S. aquifers, findings from this study are applicable elsewhere that have mean recharge rates between 3.65 and 730 mm yr–1. We find that mean infiltration flux, period of time varying infiltration, and hydraulic conductivity are statistically significant predictors of damping depth. The resulting framework explains why some periodic infiltration fluxes associated with climate variability dampen with depth in the vadose zone, resulting in steady-state recharge, while other periodic surface fluxes do not dampen with depth, resulting in transient recharge. We find that transient recharge in response to the climate variability patterns could be detected at the depths of water levels in most U.S. aquifers. Our findings indicate that the damping behavior of transient infiltration fluxes is linear across soil layers for a range of texture combinations. The implications are that relatively simple, homogeneous models of the vadose zone may provide reasonable estimates of the damping depth of climate-varying transient recharge in some complex, layered vadose zone profiles.
Suppression of thermal transients in advanced LIGO interferometers using CO2 laser preheating
NASA Astrophysics Data System (ADS)
Jaberian Hamedan, V.; Zhao, C.; Ju, L.; Blair, C.; Blair, D. G.
2018-06-01
In high optical power interferometric gravitational wave detectors, such as Advanced LIGO, the thermal effects due to optical absorption in the mirror coatings and the slow thermal response of fused silica substrate cause time dependent changes in the mirror profile. After locking, high optical power builds up in the arm cavities. Absorption induced heating causes optical cavity transverse mode frequencies to drift over a period of hours, relative to the fundamental mode. At high optical power this can cause time dependent transient parametric instability, which can lead to interferometer disfunction. In this paper, we model the use of CO2 laser heating designed to enable the interferometer to be maintained in a thermal condition such that transient changes in the mirrors are greatly reduced. This can minimize transient parametric instability and compensate dark port power fluctuations. Modeling results are presented for both single compensation where a CO2 laser acting on one test mass per cavity, and double compensation using one CO2 laser for each test mass. Using parameters of the LIGO Hanford Observatory X-arm as an example, single compensation allows the maximum mode frequency shift to be limited to 6% of its uncompensated value. However, single compensation causes transient degradation of the contrast defect. Double compensation minimise contrast defect degradation and reduces transients to less than 1% if the CO2 laser spot is positioned within 2 mm of the cavity beam position.
NASA Astrophysics Data System (ADS)
Deng, Jiechun; Xu, Haiming; Shi, Ning; Zhang, Leying; Ma, Jing
2017-08-01
Roles of the Tibetan Plateau (TP) in forming and changing the seasonal Asian climate system have been widely explored. However, little is known about modulation effects of the TP on extratropical transient eddies (TEs) and subsequent synoptic responses of the East Asian rainfall. In this study, the Community Atmosphere Model version 5.1 coupled with a slab ocean model is employed to highlight the important role of the TP in regulating the upper-tropospheric transient wave train. Comparison between sensitivity experiments with and without the TP shows that the northern TP excites a strong anomalous anticyclone, which shifts the upper-level East Asian westerly jet northward and helps transfer barotropic and baroclinic energy from the mean flow to the synoptic TE flow. The transient wave train is primarily shifted northward by northern TP and is forced to propagate southeastward along the eastern flank of the TP until reaching eastern China. Before the strengthening of monsoonal southerlies, the TP-modulated transient wave train cools the troposphere, which decreases the static stability over northern China. Meanwhile, the associated anomalous warm advection induces ascending motion, leading to excessive rainfall by releasing unstable energy as the southerly strengthens. Due to the southeastward propagation of the wave train, anomalous heavy rainfall subsequently appears over eastern China from north to south, which increases day-to-day rainfall variation in this region. Additionally, occurrence of this upper-tropospheric transient wave train associated with low-level southerly peak is substantially increased by northern TP.
Martin, Nellie Anne; Bonner, Helena; Elkjær, Maria Louise; D’Orsi, Beatrice; Chen, Gang; König, Hans Georg; Svensson, Martina; Deierborg, Tomas; Pfeiffer, Shona; Prehn, Jochen H.; Lambertsen, Kate Lykke
2016-01-01
The BH3 interacting-domain death agonist (BID) is a pro-apoptotic protein involved in death receptor-induced and mitochondria-mediated apoptosis. Recently, it has also been suggested that BID is involved in the regulation of inflammatory responses in the central nervous system. We found that BID deficiency protected organotypic hippocampal slice cultures in vitro from neuronal injury induced by oxygen-glucose deprivation. In vivo, BID-knockout (KO) mice and wild type (WT) mice were subjected to 60 min of transient middle cerebral artery occlusion (tMCAO) to induce focal cerebral ischemia, and allowed to recover for 24 h. Infarct volumes and functional outcome were assessed and the inflammatory response was evaluated using immunofluorescence, Western blotting, quantitative PCR (qPCR) and Mesoscale multiplex analysis. We observed no difference in the infarct volume or neurological outcome between BID-KO and WT mice. The inflammatory response was reduced by BID deficiency as indicated by a change in microglial/leukocyte response. In conclusion, our data suggest that BID deficiency is neuroprotective in an in vitro model and modulates the inflammatory response to focal cerebral ischemia in vivo. However, this is not translated into a robust neuroprotection in vivo. PMID:26869884
Long-Lasting Crossmodal Cortical Reorganization Triggered by Brief Postnatal Visual Deprivation.
Collignon, Olivier; Dormal, Giulia; de Heering, Adelaide; Lepore, Franco; Lewis, Terri L; Maurer, Daphne
2015-09-21
Animal and human studies have demonstrated that transient visual deprivation early in life, even for a very short period, permanently alters the response properties of neurons in the visual cortex and leads to corresponding behavioral visual deficits. While it is acknowledged that early-onset and longstanding blindness leads the occipital cortex to respond to non-visual stimulation, it remains unknown whether a short and transient period of postnatal visual deprivation is sufficient to trigger crossmodal reorganization that persists after years of visual experience. In the present study, we characterized brain responses to auditory stimuli in 11 adults who had been deprived of all patterned vision at birth by congenital cataracts in both eyes until they were treated at 9 to 238 days of age. When compared to controls with typical visual experience, the cataract-reversal group showed enhanced auditory-driven activity in focal visual regions. A combination of dynamic causal modeling with Bayesian model selection indicated that this auditory-driven activity in the occipital cortex was better explained by direct cortico-cortical connections with the primary auditory cortex than by subcortical connections. Thus, a short and transient period of visual deprivation early in life leads to enduring large-scale crossmodal reorganization of the brain circuitry typically dedicated to vision. Copyright © 2015 Elsevier Ltd. All rights reserved.
Weitlauf, Carl; Ward, Nicholas J; Lambert, Wendi S; Sidorova, Tatiana N; Ho, Karen W; Sappington, Rebecca M; Calkins, David J
2014-11-12
Progression of neurodegeneration in disease and injury is influenced by the response of individual neurons to stressful stimuli and whether this response includes mechanisms to counter declining function. Transient receptor potential (TRP) cation channels transduce a variety of disease-relevant stimuli and can mediate diverse stress-dependent changes in physiology, both presynaptic and postsynaptic. Recently, we demonstrated that knock-out or pharmacological inhibition of the TRP vanilloid-1 (TRPV1) capsaicin-sensitive subunit accelerates degeneration of retinal ganglion cell neurons and their axons with elevated ocular pressure, the critical stressor in the most common optic neuropathy, glaucoma. Here we probed the mechanism of the influence of TRPV1 on ganglion cell survival in mouse models of glaucoma. We found that induced elevations of ocular pressure increased TRPV1 in ganglion cells and its colocalization at excitatory synapses to their dendrites, whereas chronic elevation progressively increased ganglion cell Trpv1 mRNA. Enhanced TRPV1 expression in ganglion cells was transient and supported a reversal of the effect of TRPV1 on ganglion cells from hyperpolarizing to depolarizing, which was also transient. Short-term enhancement of TRPV1-mediated activity led to a delayed increase in axonal spontaneous excitation that was absent in ganglion cells from Trpv1(-/-) retina. In isolated ganglion cells, pharmacologically activated TRPV1 mobilized to discrete nodes along ganglion cell dendrites that corresponded to sites of elevated Ca(2+). These results suggest that TRPV1 may promote retinal ganglion cell survival through transient enhancement of local excitation and axonal activity in response to ocular stress. Copyright © 2014 the authors 0270-6474/14/3415369-13$15.00/0.
NASA Astrophysics Data System (ADS)
Porter, Ian Edward
A nuclear reactor systems code has the ability to model the system response in an accident scenario based on known initial conditions at the onset of the transient. However, there has been a tendency for these codes to lack the detailed thermo-mechanical fuel rod response models needed for accurate prediction of fuel rod failure. This proposed work will couple today's most widely used steady-state (FRAPCON) and transient (FRAPTRAN) fuel rod models with a systems code TRACE for best-estimate modeling of system response in accident scenarios such as a loss of coolant accident (LOCA). In doing so, code modifications will be made to model gamma heating in LWRs during steady-state and accident conditions and to improve fuel rod thermal/mechanical analysis by allowing axial nodalization of burnup-dependent phenomena such as swelling, cladding creep and oxidation. With the ability to model both burnup-dependent parameters and transient fuel rod response, a fuel dispersal study will be conducted using a hypothetical accident scenario under both PWR and BWR conditions to determine the amount of fuel dispersed under varying conditions. Due to the fuel fragmentation size and internal rod pressure both being dependent on burnup, this analysis will be conducted at beginning, middle and end of cycle to examine the effects that cycle time can play on fuel rod failure and dispersal. Current fuel rod and system codes used by the Nuclear Regulatory Commission (NRC) are compilations of legacy codes with only commonly used light water reactor materials, Uranium Dioxide (UO2), Mixed Oxide (U/PuO 2) and zirconium alloys. However, the events at Fukushima Daiichi and Three Mile Island accident have shown the need for exploration into advanced materials possessing improved accident tolerance. This work looks to further modify the NRC codes to include silicon carbide (SiC), an advanced cladding material proposed by current DOE funded research on accident tolerant fuels (ATF). Several additional fuels will also be analyzed, including uranium nitride (UN), uranium carbide (UC) and uranium silicide (U3Si2). Focusing on the system response in an accident scenario, an emphasis is placed on the fracture mechanics of the ceramic cladding by design the fuel rods to eliminate pellet cladding mechanical interaction (PCMI). The time to failure and how much of the fuel in the reactor fails with an advanced fuel design will be analyzed and compared to the current UO2/Zircaloy design using a full scale reactor model.
THETRIS: A MICRO-SCALE TEMPERATURE AND GAS RELEASE MODEL FOR TRISO FUEL
DOE Office of Scientific and Technical Information (OSTI.GOV)
J. Ortensi; A.M. Ougouag
2011-12-01
The dominating mechanism in the passive safety of gas-cooled, graphite-moderated, high-temperature reactors (HTRs) is the Doppler feedback effect. These reactor designs are fueled with sub-millimeter sized kernels formed into TRISO particles that are imbedded in a graphite matrix. The best spatial and temporal representation of the feedback effect is obtained from an accurate approximation of the fuel temperature. Most accident scenarios in HTRs are characterized by large time constants and slow changes in the fuel and moderator temperature fields. In these situations a meso-scale, pebble and compact scale, solution provides a good approximation of the fuel temperature. Micro-scale models aremore » necessary in order to obtain accurate predictions in faster transients or when parameters internal to the TRISO are needed. Since these coated particles constitute one of the fundamental design barriers for the release of fission products, it becomes important to understand the transient behavior inside this containment system. An explicit TRISO fuel temperature model named THETRIS has been developed and incorporated into the CYNOD-THERMIX-KONVEK suite of coupled codes. The code includes gas release models that provide a simple predictive capability of the internal pressure during transients. The new model yields similar results to those obtained with other micro-scale fuel models, but with the added capability to analyze gas release, internal pressure buildup, and effects of a gap in the TRISO. The analyses show the instances when the micro-scale models improve the predictions of the fuel temperature and Doppler feedback. In addition, a sensitivity study of the potential effects on the transient behavior of high-temperature reactors due to the presence of a gap is included. Although the formation of a gap occurs under special conditions, its consequences on the dynamic behavior of the reactor can cause unexpected responses during fast transients. Nevertheless, the strong Doppler feedback forces the reactor to quickly stabilize.« less
Ant groups optimally amplify the effect of transiently informed individuals
NASA Astrophysics Data System (ADS)
Gelblum, Aviram; Pinkoviezky, Itai; Fonio, Ehud; Ghosh, Abhijit; Gov, Nir; Feinerman, Ofer
2015-07-01
To cooperatively transport a large load, it is important that carriers conform in their efforts and align their forces. A downside of behavioural conformism is that it may decrease the group's responsiveness to external information. Combining experiment and theory, we show how ants optimize collective transport. On the single-ant scale, optimization stems from decision rules that balance individuality and compliance. Macroscopically, these rules poise the system at the transition between random walk and ballistic motion where the collective response to the steering of a single informed ant is maximized. We relate this peak in response to the divergence of susceptibility at a phase transition. Our theoretical models predict that the ant-load system can be transitioned through the critical point of this mesoscopic system by varying its size; we present experiments supporting these predictions. Our findings show that efficient group-level processes can arise from transient amplification of individual-based knowledge.
Hagan, Cindy C; Woods, Will; Johnson, Sam; Calder, Andrew J; Green, Gary G R; Young, Andrew W
2009-11-24
An influential neural model of face perception suggests that the posterior superior temporal sulcus (STS) is sensitive to those aspects of faces that produce transient visual changes, including facial expression. Other researchers note that recognition of expression involves multiple sensory modalities and suggest that the STS also may respond to crossmodal facial signals that change transiently. Indeed, many studies of audiovisual (AV) speech perception show STS involvement in AV speech integration. Here we examine whether these findings extend to AV emotion. We used magnetoencephalography to measure the neural responses of participants as they viewed and heard emotionally congruent fear and minimally congruent neutral face and voice stimuli. We demonstrate significant supra-additive responses (i.e., where AV > [unimodal auditory + unimodal visual]) in the posterior STS within the first 250 ms for emotionally congruent AV stimuli. These findings show a role for the STS in processing crossmodal emotive signals.
Ant groups optimally amplify the effect of transiently informed individuals
Gelblum, Aviram; Pinkoviezky, Itai; Fonio, Ehud; Ghosh, Abhijit; Gov, Nir; Feinerman, Ofer
2015-01-01
To cooperatively transport a large load, it is important that carriers conform in their efforts and align their forces. A downside of behavioural conformism is that it may decrease the group's responsiveness to external information. Combining experiment and theory, we show how ants optimize collective transport. On the single-ant scale, optimization stems from decision rules that balance individuality and compliance. Macroscopically, these rules poise the system at the transition between random walk and ballistic motion where the collective response to the steering of a single informed ant is maximized. We relate this peak in response to the divergence of susceptibility at a phase transition. Our theoretical models predict that the ant-load system can be transitioned through the critical point of this mesoscopic system by varying its size; we present experiments supporting these predictions. Our findings show that efficient group-level processes can arise from transient amplification of individual-based knowledge. PMID:26218613
Application of the finite element groundwater model FEWA to the engineered test facility
DOE Office of Scientific and Technical Information (OSTI.GOV)
Craig, P.M.; Davis, E.C.
1985-09-01
A finite element model for water transport through porous media (FEWA) has been applied to the unconfined aquifer at the Oak Ridge National Laboratory Solid Waste Storage Area 6 Engineered Test Facility (ETF). The model was developed in 1983 as part of the Shallow Land Burial Technology - Humid Task (ONL-WL14) and was previously verified using several general hydrologic problems for which an analytic solution exists. Model application and calibration, as described in this report, consisted of modeling the ETF water table for three specialized cases: a one-dimensional steady-state simulation, a one-dimensional transient simulation, and a two-dimensional transient simulation. Inmore » the one-dimensional steady-state simulation, the FEWA output accurately predicted the water table during a long period in which there were no man-induced or natural perturbations to the system. The input parameters of most importance for this case were hydraulic conductivity and aquifer bottom elevation. In the two transient cases, the FEWA output has matched observed water table responses to a single rainfall event occurring in February 1983, yielding a calibrated finite element model that is useful for further study of additional precipitation events as well as contaminant transport at the experimental site.« less
Chouet, Bernard A.; Dawson, Phillip B.; Nakano, Masaru
2006-01-01
We present a model of gas exsolution and bubble expansion in a melt supersaturated in response to a sudden pressure drop. In our model, the melt contains a suspension of gas bubbles of identical sizes and is encased in a penny-shaped crack embedded in an elastic solid. The suspension is modeled as a three-dimensional lattice of spherical cells with slight overlap, where each elementary cell consists of a gas bubble surrounded by a shell of volatile-rich melt. The melt is then subjected to a step drop in pressure, which induces gas exsolution and bubble expansion, resulting in the compression of the melt and volumetric expansion of the crack. The dynamics of diffusion-driven bubble growth and volumetric crack expansion span 9 decades in time. The model demonstrates that the speed of the crack response depends strongly on volatile diffusivity in the melt and bubble number density and is markedly sensitive to the ratio of crack thickness to crack radius and initial bubble radius but is relatively insensitive to melt viscosity. The net drop in gas concentration in the melt after pressure recovery represents only a small fraction of the initial concentration prior to the drop, suggesting the melt may undergo numerous pressure transients before becoming significantly depleted of gases. The magnitude of pressure and volume recovery in the crack depends sensitively on the size of the input-pressure transient, becoming relatively larger for smaller-size transients in a melt containing bubbles with initial radii less than 10-5 m. Amplification of the input transient may be large enough to disrupt the crack wall and induce brittle failure in the rock matrix surrounding the crack. Our results provide additional basis for the interpretation of volume changes in the magma conduit under Popocatépetl Volcano during Vulcanian degassing bursts in its eruptive activity in April–May 2000.
Pernik, Meribeth
1987-01-01
The sensitivity of a multilayer finite-difference regional flow model was tested by changing the calibrated values for five parameters in the steady-state model and one in the transient-state model. The parameters that changed under the steady-state condition were those that had been routinely adjusted during the calibration process as part of the effort to match pre-development potentiometric surfaces, and elements of the water budget. The tested steady-state parameters include: recharge, riverbed conductance, transmissivity, confining unit leakance, and boundary location. In the transient-state model, the storage coefficient was adjusted. The sensitivity of the model to changes in the calibrated values of these parameters was evaluated with respect to the simulated response of net base flow to the rivers, and the mean value of the absolute head residual. To provide a standard measurement of sensitivity from one parameter to another, the standard deviation of the absolute head residual was calculated. The steady-state model was shown to be most sensitive to changes in rates of recharge. When the recharge rate was held constant, the model was more sensitive to variations in transmissivity. Near the rivers, the riverbed conductance becomes the dominant parameter in controlling the heads. Changes in confining unit leakance had little effect on simulated base flow, but greatly affected head residuals. The model was relatively insensitive to changes in the location of no-flow boundaries and to moderate changes in the altitude of constant head boundaries. The storage coefficient was adjusted under transient conditions to illustrate the model 's sensitivity to changes in storativity. The model is less sensitive to an increase in storage coefficient than it is to a decrease in storage coefficient. As the storage coefficient decreased, the aquifer drawdown increases, the base flow decreased. The opposite response occurred when the storage coefficient was increased. (Author 's abstract)
NASA Astrophysics Data System (ADS)
Ou, Shiqi; Zhao, Yi; Aaron, Douglas S.; Regan, John M.; Mench, Matthew M.
2016-10-01
This work describes experiments and computational simulations to analyze single-chamber, air-cathode microbial fuel cell (MFC) performance and cathodic limitations in terms of current generation, power output, mass transport, biomass competition, and biofilm growth. Steady-state and transient cathode models were developed and experimentally validated. Two cathode gas mixtures were used to explore oxygen transport in the cathode: the MFCs exposed to a helium-oxygen mixture (heliox) produced higher current and power output than the group of MFCs exposed to air or a nitrogen-oxygen mixture (nitrox), indicating a dependence on gas-phase transport in the cathode. Multi-substance transport, biological reactions, and electrochemical reactions in a multi-layer and multi-biomass cathode biofilm were also simulated in a transient model. The transient model described biofilm growth over 15 days while providing insight into mass transport and cathodic dissolved species concentration profiles during biofilm growth. Simulation results predict that the dissolved oxygen content and diffusion in the cathode are key parameters affecting the power output of the air-cathode MFC system, with greater oxygen content in the cathode resulting in increased power output and fully-matured biomass.
Ou, Shiqi; Zhao, Yi; Aaron, Douglas S.; ...
2016-08-15
This work describes experiments and computational simulations to analyze single-chamber, air-cathode microbial fuel cell (MFC) performance and cathodic limitations in terms of current generation, power output, mass transport, biomass competition, and biofilm growth. Steady-state and transient cathode models were developed and experimentally validated. Two cathode gas mixtures were used to explore oxygen transport in the cathode: the MFCs exposed to a helium-oxygen mixture (heliox) produced higher current and power output than the group of MFCs exposed to air or a nitrogen-oxygen mixture (nitrox), indicating a dependence on gas-phase transport in the cathode. Multi-substance transport, biological reactions, and electrochemical reactions inmore » a multi-layer and multi-biomass cathode biofilm were also simulated in a transient model. The transient model described biofilm growth over 15 days while providing insight into mass transport and cathodic dissolved species concentration profiles during biofilm growth. Lastly, simulation results predict that the dissolved oxygen content and diffusion in the cathode are key parameters affecting the power output of the air-cathode MFC system, with greater oxygen content in the cathode resulting in increased power output and fully-matured biomass.« less
The impact of model detail on power grid resilience measures
NASA Astrophysics Data System (ADS)
Auer, S.; Kleis, K.; Schultz, P.; Kurths, J.; Hellmann, F.
2016-05-01
Extreme events are a challenge to natural as well as man-made systems. For critical infrastructure like power grids, we need to understand their resilience against large disturbances. Recently, new measures of the resilience of dynamical systems have been developed in the complex system literature. Basin stability and survivability respectively assess the asymptotic and transient behavior of a system when subjected to arbitrary, localized but large perturbations in frequency and phase. To employ these methods that assess power grid resilience, we need to choose a certain model detail of the power grid. For the grid topology we considered the Scandinavian grid and an ensemble of power grids generated with a random growth model. So far the most popular model that has been studied is the classical swing equation model for the frequency response of generators and motors. In this paper we study a more sophisticated model of synchronous machines that also takes voltage dynamics into account, and compare it to the previously studied model. This model has been found to give an accurate picture of the long term evolution of synchronous machines in the engineering literature for post fault studies. We find evidence that some stable fix points of the swing equation become unstable when we add voltage dynamics. If this occurs the asymptotic behavior of the system can be dramatically altered, and basin stability estimates obtained with the swing equation can be dramatically wrong. We also find that the survivability does not change significantly when taking the voltage dynamics into account. Further, the limit cycle type asymptotic behaviour is strongly correlated with transient voltages that violate typical operational voltage bounds. Thus, transient voltage bounds are dominated by transient frequency bounds and play no large role for realistic parameters.
An alternative approach to measure similarity between two deterministic transient signals
NASA Astrophysics Data System (ADS)
Shin, Kihong
2016-06-01
In many practical engineering applications, it is often required to measure the similarity of two signals to gain insight into the conditions of a system. For example, an application that monitors machinery can regularly measure the signal of the vibration and compare it to a healthy reference signal in order to monitor whether or not any fault symptom is developing. Also in modal analysis, a frequency response function (FRF) from a finite element model (FEM) is often compared with an FRF from experimental modal analysis. Many different similarity measures are applicable in such cases, and correlation-based similarity measures may be most frequently used among these such as in the case where the correlation coefficient in the time domain and the frequency response assurance criterion (FRAC) in the frequency domain are used. Although correlation-based similarity measures may be particularly useful for random signals because they are based on probability and statistics, we frequently deal with signals that are largely deterministic and transient. Thus, it may be useful to develop another similarity measure that takes the characteristics of the deterministic transient signal properly into account. In this paper, an alternative approach to measure the similarity between two deterministic transient signals is proposed. This newly proposed similarity measure is based on the fictitious system frequency response function, and it consists of the magnitude similarity and the shape similarity. Finally, a few examples are presented to demonstrate the use of the proposed similarity measure.
NASA Astrophysics Data System (ADS)
Jazebi, Saeed
This thesis is a step forward toward achieving the final objective of creating a fully dual model for transformers including eddy currents and nonlinearities of the iron core using the fundamental electrical components already available in the EMTP-type programs. The model is effective for the study of the performance of transformers during power system transients. This is very important for transformer designers, because the insulation of transformers is determined with the overvoltages caused by lightning or switching operations. There are also internally induced transients that occur when a switch is actuated. For example switching actions for reconfiguration of distribution systems that offers economic advantages, or protective actions to clear faults and large short-circuit currents. Many of the smart grid concepts currently under development by many utilities rely heavily on switching to optimize resources that produce transients in the system. On the other hand, inrush currents produce mechanical forces which deform transformer windings and cause malfunction of the differential protection. Also, transformer performance under ferroresonance and geomagnetic induced currents are necessary to study. In this thesis, a physically consistent dual model applicable to single-phase two-winding transformers is proposed. First, the topology of a dual electrical equivalent circuit is obtained from the direct application of the principle of duality. Then, the model parameters are computed considering the variations of the transformer electromagnetic behavior under various operating conditions. Current modeling techniques use different topological models to represent diverse transient situations. The reversible model proposed in this thesis unifies the terminal and topological equivalent circuits. The model remains invariable for all low-frequency transients including deep saturation conditions driven from any of the two windings. The very high saturation region of the iron core magnetizing characteristic is modified with the accurate measurement of the air-core inductance. The air-core inductance is measured using a non-ideal low-power rectifier. Its dc output serves to drive the transformer into deep saturation, and its ripple provides low-amplitude variable excitation. The principal advantage of this method is its simplicity. To model the eddy current effects in the windings, a novel equivalent circuit is proposed. The circuit is derived from the principle of duality and therefore, matches the electromagnetic physical behavior of the transformer windings. It properly models the flux paths and current distribution from dc to MHz. The model is synthesized from a non-uniform concentric discretization of the windings. Concise guidelines are given to optimally calculate the width of the sub-divisions for various transient simulations. To compute the circuit parameters only information about the geometry of the windings and about their material properties is needed. The calculation of the circuit parameters does not require an iterative process. Therefore, the parameters are always real, positive, and free from convergence problems. The proposed model is tested with single-phase transformers for the calculation of magnetizing inrush currents, series ferroresonance, and Geomagnetic Induced Currents (GIC). The electromagnetic transient response of the model is compared to laboratory measurements for validation. Also, 3D finite element simulations are used to validate the electromagnetic behavior of the transformer model. Large manufacturer of transformers, power system designers, and electrical utility companies can benefit from the new model. It simplifies the design and optimization of the transformers' insulation, thereby reducing cost, and enhancing reliability of the system. The model could also be used for inrush current and differential protection studies, geomagnetic induced current studies, harmonic penetration studies, and switching transient studies.
Dynamic Modeling of Solar Dynamic Components and Systems
NASA Technical Reports Server (NTRS)
Hochstein, John I.; Korakianitis, T.
1992-01-01
The purpose of this grant was to support NASA in modeling efforts to predict the transient dynamic and thermodynamic response of the space station solar dynamic power generation system. In order to meet the initial schedule requirement of providing results in time to support installation of the system as part of the initial phase of space station, early efforts were executed with alacrity and often in parallel. Initially, methods to predict the transient response of a Rankine as well as a Brayton cycle were developed. Review of preliminary design concepts led NASA to select a regenerative gas-turbine cycle using a helium-xenon mixture as the working fluid and, from that point forward, the modeling effort focused exclusively on that system. Although initial project planning called for a three year period of performance, revised NASA schedules moved system installation to later and later phases of station deployment. Eventually, NASA selected to halt development of the solar dynamic power generation system for space station and to reduce support for this project to two-thirds of the original level.
Echeverría, E L; Robles, L W
1983-02-01
Cochlear microphonic (CM) responses to acoustic transient stimuli were studied at the three more basal turns of the cochlea in the guinea pig. The responses to rarefaction and condensation pressure pulses of less than 100-mus duration were recorded using the differential electrode technique. In some animals the CM response to pure tones was recorded at the same position at which the transient response was obtained. The transient responses recorded at the three turns of the cochlea displayed a damped oscillation at a frequency consistent with the values of cutoff frequency already known for the electrode positions. Some of the responses were significantly less damped than click responses previously reported. There was a good correlation between the cutoff frequency in the frequency response curve and the frequency of oscillation in the transient response for recordings obtained at the same position in the cochlea. A nonlinear effect was observed for changes in stimulus intensity. There was a less than proportional decrease in amplitude of the initial part of the damped oscillation for a decrease of the stimulus intensity, while the late part of the response behaved almost linearly. This nonlinearity observed in the CM transient response could not be explained by a nonlinear characteristic of the sort reported in the basilar membrane of the squirrel monkey by Robles et al. [J. Acoust. Soc. Am. 59, 926-939 (1976)]; rather it seems to be a saturation nonlinearity similar to the one known for sinusoidal stimulation.
Neurophysiological bases of exponential sensory decay and top-down memory retrieval: a model.
Zylberberg, Ariel; Dehaene, Stanislas; Mindlin, Gabriel B; Sigman, Mariano
2009-01-01
Behavioral observations suggest that multiple sensory elements can be maintained for a short time, forming a perceptual buffer which fades after a few hundred milliseconds. Only a subset of this perceptual buffer can be accessed under top-down control and broadcasted to working memory and consciousness. In turn, single-cell studies in awake-behaving monkeys have identified two distinct waves of response to a sensory stimulus: a first transient response largely determined by stimulus properties and a second wave dependent on behavioral relevance, context and learning. Here we propose a simple biophysical scheme which bridges these observations and establishes concrete predictions for neurophsyiological experiments in which the temporal interval between stimulus presentation and top-down allocation is controlled experimentally. Inspired in single-cell observations, the model involves a first transient response and a second stage of amplification and retrieval, which are implemented biophysically by distinct operational modes of the same circuit, regulated by external currents. We explicitly investigated the neuronal dynamics, the memory trace of a presented stimulus and the probability of correct retrieval, when these two stages were bracketed by a temporal gap. The model predicts correctly the dependence of performance with response times in interference experiments suggesting that sensory buffering does not require a specific dedicated mechanism and establishing a direct link between biophysical manipulations and behavioral observations leading to concrete predictions.
NASA Astrophysics Data System (ADS)
Dhakal, B.; Nicholson, D. E.; Saleeb, A. F.; Padula, S. A., II; Vaidyanathan, R.
2016-09-01
Shape memory alloy (SMA) actuators often operate under a complex state of stress for an extended number of thermomechanical cycles in many aerospace and engineering applications. Hence, it becomes important to account for multi-axial stress states and deformation characteristics (which evolve with thermomechanical cycling) when calibrating any SMA model for implementation in large-scale simulation of actuators. To this end, the present work is focused on the experimental validation of an SMA model calibrated for the transient and cyclic evolutionary behavior of shape memory Ni49.9Ti50.1, for the actuation of axially loaded helical-coil springs. The approach requires both experimental and computational aspects to appropriately assess the thermomechanical response of these multi-dimensional structures. As such, an instrumented and controlled experimental setup was assembled to obtain temperature, torque, degree of twist and extension, while controlling end constraints during heating and cooling of an SMA spring under a constant externally applied axial load. The computational component assesses the capabilities of a general, multi-axial, SMA material-modeling framework, calibrated for Ni49.9Ti50.1 with regard to its usefulness in the simulation of SMA helical-coil spring actuators. Axial extension, being the primary response, was examined on an axially-loaded spring with multiple active coils. Two different conditions of end boundary constraint were investigated in both the numerical simulations as well as the validation experiments: Case (1) where the loading end is restrained against twist (and the resulting torque measured as the secondary response) and Case (2) where the loading end is free to twist (and the degree of twist measured as the secondary response). The present study focuses on the transient and evolutionary response associated with the initial isothermal loading and the subsequent thermal cycles under applied constant axial load. The experimental results for the helical-coil actuator under two different boundary conditions are found to be within error to their counterparts in the numerical simulations. The numerical simulation and the experimental validation demonstrate similar transient and evolutionary behavior in the deformation response under the complex, inhomogeneous, multi-axial stress-state and large deformations of the helical-coil actuator. This response, although substantially different in magnitude, exhibited similar evolutionary characteristics to the simple, uniaxial, homogeneous, stress-state of the isobaric tensile tests results used for the model calibration. There was no significant difference in the axial displacement (primary response) magnitudes observed between Cases (1) and (2) for the number of cycles investigated here. The simulated secondary responses of the two cases evolved in a similar manner when compared to the experimental validation of the respective cases.
Parameterized and resolved Southern Ocean eddy compensation
NASA Astrophysics Data System (ADS)
Poulsen, Mads B.; Jochum, Markus; Nuterman, Roman
2018-04-01
The ability to parameterize Southern Ocean eddy effects in a forced coarse resolution ocean general circulation model is assessed. The transient model response to a suite of different Southern Ocean wind stress forcing perturbations is presented and compared to identical experiments performed with the same model in 0.1° eddy-resolving resolution. With forcing of present-day wind stress magnitude and a thickness diffusivity formulated in terms of the local stratification, it is shown that the Southern Ocean residual meridional overturning circulation in the two models is different in structure and magnitude. It is found that the difference in the upper overturning cell is primarily explained by an overly strong subsurface flow in the parameterized eddy-induced circulation while the difference in the lower cell is mainly ascribed to the mean-flow overturning. With a zonally constant decrease of the zonal wind stress by 50% we show that the absolute decrease in the overturning circulation is insensitive to model resolution, and that the meridional isopycnal slope is relaxed in both models. The agreement between the models is not reproduced by a 50% wind stress increase, where the high resolution overturning decreases by 20%, but increases by 100% in the coarse resolution model. It is demonstrated that this difference is explained by changes in surface buoyancy forcing due to a reduced Antarctic sea ice cover, which strongly modulate the overturning response and ocean stratification. We conclude that the parameterized eddies are able to mimic the transient response to altered wind stress in the high resolution model, but partly misrepresent the unperturbed Southern Ocean meridional overturning circulation and associated heat transports.
NASA Technical Reports Server (NTRS)
Brown, Andrew M.; Schmauch, Preston
2012-01-01
Turbine blades in rocket and jet engine turbomachinery experience enormous harmonic loading conditions. These loads result from the integer number of upstream and downstream stator vanes as well as the other turbine stages. The standard technique for forced response analysis to assess structural integrity is to decompose a CFD generated flow field into its harmonic components, and to then perform a frequency response analysis at the problematic natural frequencies. Recent CFD analysis and water-flow testing at NASA/MSFC, though, indicates that this technique may miss substantial harmonic and non-harmonic excitation sources that become present in complex flows. These complications suggest the question of whether frequency domain analysis is capable of capturing the excitation content sufficiently. Two studies comparing frequency response analysis with transient response analysis, therefore, have been performed. The first is of a bladed disk with each blade modeled by simple beam elements. It was hypothesized that the randomness and other variation from the standard harmonic excitation would reduce the blade structural response, but the results showed little reduction. The second study was of a realistic model of a bladed-disk excited by the same CFD used in the J2X engine program. The results showed that the transient analysis results were up to 10% higher for "clean" nodal diameter excitations and six times larger for "messy" excitations, where substantial Fourier content around the main harmonic exists.
Numerical analysis of transient laminar forced convection of nanofluids in circular ducts
NASA Astrophysics Data System (ADS)
Sert, İsmail Ozan; Sezer-Uzol, Nilay; Kakaç, Sadık
2013-10-01
In this study, forced convection heat transfer characteristics of nanofluids are investigated by numerical analysis of incompressible transient laminar flow in a circular duct under step change in wall temperature and wall heat flux. The thermal responses of the system are obtained by solving energy equation under both transient and steady-state conditions for hydro-dynamically fully-developed flow. In the analyses, temperature dependent thermo-physical properties are also considered. In the numerical analysis, Al2O3/water nanofluid is assumed as a homogenous single-phase fluid. For the effective thermal conductivity of nanofluids, Hamilton-Crosser model is used together with a model for Brownian motion in the analysis which takes the effects of temperature and the particle diameter into account. Temperature distributions across the tube for a step jump of wall temperature and also wall heat flux are obtained for various times during the transient calculations at a given location for a constant value of Peclet number and a particle diameter. Variations of thermal conductivity in turn, heat transfer enhancement is obtained at various times as a function of nanoparticle volume fractions, at a given nanoparticle diameter and Peclet number. The results are given under transient and steady-state conditions; steady-state conditions are obtained at larger times and enhancements are found by comparison to the base fluid heat transfer coefficient under the same conditions.
NASA Technical Reports Server (NTRS)
Greene, William H.
1989-01-01
A study has been performed focusing on the calculation of sensitivities of displacements, velocities, accelerations, and stresses in linear, structural, transient response problems. One significant goal was to develop and evaluate sensitivity calculation techniques suitable for large-order finite element analyses. Accordingly, approximation vectors such as vibration mode shapes are used to reduce the dimensionality of the finite element model. Much of the research focused on the accuracy of both response quantities and sensitivities as a function of number of vectors used. Two types of sensitivity calculation techniques were developed and evaluated. The first type of technique is an overall finite difference method where the analysis is repeated for perturbed designs. The second type of technique is termed semianalytical because it involves direct, analytical differentiation of the equations of motion with finite difference approximation of the coefficient matrices. To be computationally practical in large-order problems, the overall finite difference methods must use the approximation vectors from the original design in the analyses of the perturbed models.
A 3-D SPH model for simulating water flooding of a damaged floating structure
NASA Astrophysics Data System (ADS)
Guo, Kai; Sun, Peng-nan; Cao, Xue-yan; Huang, Xiao
2017-10-01
With the quasi-static analysis method, the terminal floating state of a damaged ship is usually evaluated for the risk assessment. But this is not enough since the ship has the possibility to lose its stability during the transient flooding process. Therefore, an enhanced smoothed particle hydrodynamics (SPH) model is applied in this paper to investigate the response of a simplified cabin model under the condition of the transient water flooding. The enhanced SPH model is presented firstly including the governing equations, the diffusive terms, the boundary implementations and then an algorithm regarding the coupling motions of six degrees of freedom (6-DOF) between the structure and the fluid is described. In the numerical results, a non-damaged cabin floating under the rest condition is simulated. It is shown that a stable floating state can be reached and maintained by using the present SPH scheme. After that, three-dimensional (3-D) test cases of the damaged cabin with a hole at different locations are simulated. A series of model tests are also carried out for the validation. Fairly good agreements are achieved between the numerical results and the experimental data. Relevant conclusions are drawn with respect to the mechanism of the responses of the damaged cabin model under water flooding conditions.
Transient thermohydraulic heat pipe modeling
NASA Astrophysics Data System (ADS)
Hall, Michael L.; Doster, Joseph M.
Many space based reactor designs employ heat pipes as a means of conveying heat. In these designs, thermal radiation is the principle means for rejecting waste heat from the reactor system, making it desirable to operate at high temperatures. Lithium is generally the working fluid of choice as it undergoes a liquid-vapor transformation at the preferred operating temperature. The nature of remote startup, restart, and reaction to threats necessitates an accurate, detailed transient model of the heat pipe operation. A model is outlined of the vapor core region of the heat pipe which is part of a large model of the entire heat pipe thermal response. The vapor core is modeled using the area averaged Navier-Stokes equations in one dimension, which take into account the effects of mass, energy and momentum transfer. The core model is single phase (gaseous), but contains two components: lithium gas and a noncondensible vapor. The vapor core model consists of the continuity equations for the mixture and noncondensible, as well as mixture equations for internal energy and momentum.
Jensch, Antje; Thomaseth, Caterina; Radde, Nicole E
2017-01-25
Positive and negative feedback loops are ubiquitous motifs in biochemical signaling pathways. The mitogen-activated protein kinase (MAPK) pathway module is part of many distinct signaling networks and comprises several of these motifs, whose functioning depends on the cell line at hand and on the particular context. The maintainance of specificity of the response of the MAPK module to distinct stimuli has become a key paradigm especially in PC-12 cells, where the same module leads to different cell fates, depending on the stimulating growth factor. This cell fate is regulated by differences in the ERK (MAPK) activation profile, which shows a transient response upon stimulation with EGF, while the response is sustained in case of NGF. This behavior was explained by different effective network topologies. It is widely believed that this sustained response requires a bistable system. In this study we present a sampling-based Bayesian model analysis on a dataset, in which PC-12 cells have been stimulated with different growth factors. This is combined with novel analysis methods to investigate the role of feedback interconnections to shape ERK response. Results strongly suggest that, besides bistability, an additional effect called quasi-bistability can contribute to explain the observed responses of the system to different stimuli. Quasi-bistability is the ability of a monostable system to maintain two distinct states over a long time period upon a transient signal, which is also related to positive feedback, but cannot be detected by standard steady state analysis methods. Although applied on a specific example, our framework is generic enough to be also relevant for other regulatory network modeling studies that comprise positive feedback to explain cellular decision making processes. Overall, this study advices to focus not only on steady states, but also to take transient behavior into account in the analysis.
Transient thermal analysis for radioactive liquid mixing operations in a large-scaled tank
Lee, S. Y.; Smith, III, F. G.
2014-07-25
A transient heat balance model was developed to assess the impact of a Submersible Mixer Pump (SMP) on radioactive liquid temperature during the process of waste mixing and removal for the high-level radioactive materials stored in Savannah River Site (SRS) tanks. The model results will be mainly used to determine the SMP design impacts on the waste tank temperature during operations and to develop a specification for a new SMP design to replace existing longshaft mixer pumps used during waste removal. The present model was benchmarked against the test data obtained by the tank measurement to examine the quantitative thermalmore » response of the tank and to establish the reference conditions of the operating variables under no SMP operation. The results showed that the model predictions agreed with the test data of the waste temperatures within about 10%.« less
Modeling of outgassing and matrix decomposition in carbon-phenolic composites
NASA Technical Reports Server (NTRS)
Mcmanus, Hugh L.
1994-01-01
Work done in the period Jan. - June 1994 is summarized. Two threads of research have been followed. First, the thermodynamics approach was used to model the chemical and mechanical responses of composites exposed to high temperatures. The thermodynamics approach lends itself easily to the usage of variational principles. This thermodynamic-variational approach has been applied to the transpiration cooling problem. The second thread is the development of a better algorithm to solve the governing equations resulting from the modeling. Explicit finite difference method is explored for solving the governing nonlinear, partial differential equations. The method allows detailed material models to be included and solution on massively parallel supercomputers. To demonstrate the feasibility of the explicit scheme in solving nonlinear partial differential equations, a transpiration cooling problem was solved. Some interesting transient behaviors were captured such as stress waves and small spatial oscillations of transient pressure distribution.
The modeling and simulation of visuospatial working memory
Liang, Lina; Zhang, Zhikang
2010-01-01
Camperi and Wang (Comput Neurosci 5:383–405, 1998) presented a network model for working memory that combines intrinsic cellular bistability with the recurrent network architecture of the neocortex. While Fall and Rinzel (Comput Neurosci 20:97–107, 2006) replaced this intrinsic bistability with a biological mechanism-Ca2+ release subsystem. In this study, we aim to further expand the above work. We integrate the traditional firing-rate network with Ca2+ subsystem-induced bistability, amend the synaptic weights and suggest that Ca2+ concentration only increase the efficacy of synaptic input but has nothing to do with the external input for the transient cue. We found that our network model maintained the persistent activity in response to a brief transient stimulus like that of the previous two models and the working memory performance was resistant to noise and distraction stimulus if Ca2+ subsystem was tuned to be bistable. PMID:22132045
A framework for studying transient dynamics of population projection matrix models.
Stott, Iain; Townley, Stuart; Hodgson, David James
2011-09-01
Empirical models are central to effective conservation and population management, and should be predictive of real-world dynamics. Available modelling methods are diverse, but analysis usually focuses on long-term dynamics that are unable to describe the complicated short-term time series that can arise even from simple models following ecological disturbances or perturbations. Recent interest in such transient dynamics has led to diverse methodologies for their quantification in density-independent, time-invariant population projection matrix (PPM) models, but the fragmented nature of this literature has stifled the widespread analysis of transients. We review the literature on transient analyses of linear PPM models and synthesise a coherent framework. We promote the use of standardised indices, and categorise indices according to their focus on either convergence times or transient population density, and on either transient bounds or case-specific transient dynamics. We use a large database of empirical PPM models to explore relationships between indices of transient dynamics. This analysis promotes the use of population inertia as a simple, versatile and informative predictor of transient population density, but criticises the utility of established indices of convergence times. Our findings should guide further development of analyses of transient population dynamics using PPMs or other empirical modelling techniques. © 2011 Blackwell Publishing Ltd/CNRS.
NASA Astrophysics Data System (ADS)
Yu, Pingchao; Zhang, Dayi; Ma, Yanhong; Hong, Jie
2018-06-01
Fan Blade Out (FBO) from a running rotor of the turbofan engine will not only introduce the sudden unbalance and inertia asymmetry into the rotor, but also apply large impact load and induce rotor-to-stator rubbing on the rotor, which makes the mass, gyroscopic and stiffness matrixes of the dynamic equation become time-varying and highly nonlinear, consequently leads to the system's complicated vibration. The dynamic analysis of the aero-engine rotor system is one essential requirement of the authorities and is vital to the aero-engine's safety. The paper aims at studying the dynamic responses of the complicated dual-rotor systems at instantaneous and windmilling statuses when FBO event occurs. The physical process and mechanical characteristics of the FBO event are described qualitatively, based on which the dynamic modeling for an aero-engine dual-rotor system is carried out considering several excitations caused by FBO. Meanwhile the transient response during the instantaneous status and steady-state response at the windmilling status are obtained. The results reveal that the sudden unbalance can induce impact load to the rotor, and lead to the sharp increase of the vibration amplitude and reaction force. The rub-impact will apply constraint effects on the rotor and restrict the transient vibration amplitude, while the inertia asymmetry has little influence on the transient response. When the rotor with huge unbalance operates at windmilling status, the rub-impact turns to be the main factor determining the rotor's dynamic behavior, and several potential motion states, such as instable dry whip, intermittent rubbing and synchronous full annular rubbing would happen on certain conditions.
Application of Probabilistic Analysis to Aircraft Impact Dynamics
NASA Technical Reports Server (NTRS)
Lyle, Karen H.; Padula, Sharon L.; Stockwell, Alan E.
2003-01-01
Full-scale aircraft crash simulations performed with nonlinear, transient dynamic, finite element codes can incorporate structural complexities such as: geometrically accurate models; human occupant models; and advanced material models to include nonlinear stressstrain behaviors, laminated composites, and material failure. Validation of these crash simulations is difficult due to a lack of sufficient information to adequately determine the uncertainty in the experimental data and the appropriateness of modeling assumptions. This paper evaluates probabilistic approaches to quantify the uncertainty in the simulated responses. Several criteria are used to determine that a response surface method is the most appropriate probabilistic approach. The work is extended to compare optimization results with and without probabilistic constraints.
Modeling slip system strength evolution in Ti-7Al informed by in-situ grain stress measurements
Pagan, Darren C.; Shade, Paul A; Barton, Nathan R.; ...
2017-02-17
Far-field high-energy X-ray diffraction microscopy is used to asses the evolution of slip system strengths in hexagonal close-packed (HCP) Ti-7A1 during tensile deformation in-situ. The following HCP slip system families are considered: basal < a >, prismatic < a >, pyramidal < a >, and first-order pyramidal < c + a >. A 1 mm length of the specimen's gauge section, marked with fiducials and comprised of an aggregate of over 500 grains, is tracked during continuous deformation. The response of each slip system family is quantified using 'slip system strength curves' that are calculated from the average stress tensorsmore » of each grain over the applied deformation history. These curves, which plot the average resolved shear stress for each slip system family versus macroscopic strain, represent a mesoscopic characterization of the aggregate response. A short time-scale transient softening is observed in the basal < a >, prismatic < a >, and pyramidal < a > slip systems, while a long time-scale transient hardening is observed in the pyramidal < c + a > slip systems. These results are used to develop a slip system strength model as part of an elasto-viscoplastic constitutive model for the single crystal behavior. A suite of finite element simulations is performed on a virtual polycrystal to demonstrate the relative effects of the different parameters in the slip system strength model. Finally, the model is shown to accurately capture the macroscopic stress-strain response using parameters that are chosen to capture the mesoscopic slip system responses.« less
Bahraminejad, Behzad; Basri, Shahnor; Isa, Maryam; Hambli, Zarida
2010-01-01
In this study, the ability of the Capillary-attached conductive gas sensor (CGS) in real-time gas identification was investigated. The structure of the prototype fabricated CGS is presented. Portions were selected from the beginning of the CGS transient response including the first 11 samples to the first 100 samples. Different feature extraction and classification methods were applied on the selected portions. Validation of methods was evaluated to study the ability of an early portion of the CGS transient response in target gas (TG) identification. Experimental results proved that applying extracted features from an early part of the CGS transient response along with a classifier can distinguish short-chain alcohols from each other perfectly. Decreasing time of exposition in the interaction between target gas and sensing element improved the reliability of the sensor. Classification rate was also improved and time of identification was decreased. Moreover, the results indicated the optimum interval of the early transient response of the CGS for selecting portions to achieve the best classification rates. PMID:22219666
Optical method for the determination of grain orientation in films
Maris, Humphrey J.
2001-01-01
A method for the determination of grain orientation in a film sample is provided comprising the steps of measuring a first transient optical response of the film and determining the contribution to the transient optical response arising from a change in the energy distribution of the electrons in the sample, determining the contribution to the transient optical response arising from a propagating strain pulse within the sample, and determining the contribution to the transient optical response arising from a change in sample temperature of the sample. The grain orientation of the sample may be determined using the contributions to the transient optical response arising from the change in the energy distribution of the electrons, the propagating strain pulse, and the change in sample temperature. Additionally, a method for determination of the thickness of a film sample is provided. The grain orientation of the sample is first determined. The grain orientation, together with the velocity of sound and a propagation time of a strain pulse through the sample are then used to determine the thickness of the film sample.
Optical method for the determination of grain orientation in films
Maris, Humphrey J.
2003-05-13
A method for the determination of grain orientation in a film sample is provided comprising the steps of measuring a first transient optical response of the film and determining the contribution to the transient optical response arising from a change in the energy distribution of the electrons in the sample, determining the contribution to the transient optical response arising from a propagating strain pulse within the sample, and determining the contribution to the transient optical response arising from a change in sample temperature of the sample. The grain orientation of the sample may be determined using the contributions to the transient optical response arising from the change in the energy distribution of the electrons, the propagating strain pulse, and the change in sample temperature. Additionally, a method for determination of the thickness of a film sample is provided. The grain orientation of the sample is first determined. The grain orientation, together with the velocity of sound and a propagation time of a strain pulse through the sample are then used to determine the thickness of the film sample.
NASA Astrophysics Data System (ADS)
Wu, Guohong; Shirato, Hideyuki
SCG (Superconducting Generator) has a superconducting field winding, which leads to many advantages such as small size, high generation efficiency, low impedance, and so on, and be considered as one of the candidates to meet the needs of high stability and high efficiency in the future power system networks. SCG with high response excitation is especially expected to be able to enhance the transient stability of power system by its SMES (Superconducting Magnetic Energy System) effect. The SMES effect of SCG is recognized that its behaviors are dominated by the structures and controls of its excitation system. For this reason, in order to verify exactly how the SMES effect of SCG influences on the power system stability, the electrical circuits of SCG high response excitation are modeled in detail for conducting digital simulation, and its influence on excitation voltage and active power output of SCG are discussed as well. The simulation results with a typical one machine - infinite bus power system model shows that the SMES effect can be certainly obtained when its exciting power is supplied from SCG terminal bus and may considerably lead to an improvement of power system transient stability.
NASA Astrophysics Data System (ADS)
Juang, Jia-Yang; Zheng, Jinglin
2016-10-01
Thermal responses of multilayer films play essential roles in state-of-the-art electronic systems, such as photo/micro-electronic devices, data storage systems, and silicon-on-insulator transistors. In this paper, we focus on the thermal aspects of multilayer films in the presence of a nanoscale hot spot induced by near field laser heating. The problem is set up in the scenario of heat assisted magnetic recording (HAMR), the next-generation technology to overcome the data storage density limit imposed by superparamagnetism. We characterized thermal responses of both continuous and patterned multilayer media films using transient thermal modeling. We observed that material configurations, in particular, the thermal barriers at the material layer interfaces crucially impact the temperature field hence play a key role in determining the hot spot geometry, transient response and power consumption. With a representative generic media model, we further explored the possibility of optimizing thermal performances by designing layers of heat sink and thermal barrier. The modeling approach demonstrates an effective way to characterize thermal behaviors of micro and nano-scale electronic devices with multilayer thin film structures. The insights into the thermal transport scheme will be critical for design and operations of such electronic devices.
Modeling biotic uptake by periphyton and transient hyporrheic storage of nitrate in a natural stream
Kim, Brian K.A.; Jackman, Alan P.; Triska, Frank J.
1992-01-01
To a convection-dispersion hydrologic transport model we coupled a transient storage submodel (Bencala, 1984) and a biotic uptake submodel based on Michaelis-Menten kinetics (Kim et al., 1990). Our purpose was threefold: (1) to simulate nitrate retention in response to change in load in a third-order stream, (2) to differentiate biotic versus hydrologie factors in nitrate retention, and (3) to produce a research tool whose properties are consistent with laboratory and field observations. Hydrodynamic parameters were fitted from chloride concentration during a 20-day chloride-nitrate coinjection (Bencala, 1984), and biotic uptake kinetics were based on flume studies by Kim et al. (1990) and Triska et al. (1983). Nitrate concentration from the 20-day coinjection experiment served as a base for model validation. The complete transport retention model reasonably predicted the observed nitrate concentration. However, simulations which lacked either the transient storage submodel or the biotic uptake submodel poorly predicted the observed nitrate concentration. Model simulations indicated that transient storage in channel and hyporrheic interstices dominated nitrate retention within the first 24 hours, whereas biotic uptake dominated thereafter. A sawtooth function for Vmax ranging from 0.10 to 0.17 μg NO3-N s−1 gAFDM−1 (grams ash free dry mass) slightly underpredicted nitrate retention in simulations of 2–7 days. This result was reasonable since uptake by other nitrate-demanding processes were not included. The model demonstrated how ecosystem retention is an interaction between physical and biotic processes and supports the validity of coupling separate hydrodynamic and reactive submodels to established solute transport models in biological studies of fluvial ecosystems.
Blade loss transient dynamics analysis, volume 2. Task 2: TETRA 2 user's manual
NASA Technical Reports Server (NTRS)
Black, Gerald; Gallardo, Vincente C.
1986-01-01
This is the user's manual for the TETRA 2 Computer Code, a program developed in the NASA-Lewis Blade Loss Program. TETRA 2 calculates a turbine engine's dynamic structural response from applied stimuli. The calculation options are: (1) transient response; and (2) steady state forced response. Based on the method of modal syntheses, the program allows the use of linear, as well as nonlinear connecting elements. Both transient and steady state options can include: flexible Bladed Disk Module, and Nonlinear Connecting Elements (including deadband, hardening/softening spring). The transient option has the additional capability to calculate response with a squeeze film bearing module. TETRA 2 output is summarized in a plotfile which permits post processing such as FFT or graphical animation with the proper software and computer equipment.
Identification of Synchronous Machine Stability - Parameters: AN On-Line Time-Domain Approach.
NASA Astrophysics Data System (ADS)
Le, Loc Xuan
1987-09-01
A time-domain modeling approach is described which enables the stability-study parameters of the synchronous machine to be determined directly from input-output data measured at the terminals of the machine operating under normal conditions. The transient responses due to system perturbations are used to identify the parameters of the equivalent circuit models. The described models are verified by comparing their responses with the machine responses generated from the transient stability models of a small three-generator multi-bus power system and of a single -machine infinite-bus power network. The least-squares method is used for the solution of the model parameters. As a precaution against ill-conditioned problems, the singular value decomposition (SVD) is employed for its inherent numerical stability. In order to identify the equivalent-circuit parameters uniquely, the solution of a linear optimization problem with non-linear constraints is required. Here, the SVD appears to offer a simple solution to this otherwise difficult problem. Furthermore, the SVD yields solutions with small bias and, therefore, physically meaningful parameters even in the presence of noise in the data. The question concerning the need for a more advanced model of the synchronous machine which describes subtransient and even sub-subtransient behavior is dealt with sensibly by the concept of condition number. The concept provides a quantitative measure for determining whether such an advanced model is indeed necessary. Finally, the recursive SVD algorithm is described for real-time parameter identification and tracking of slowly time-variant parameters. The algorithm is applied to identify the dynamic equivalent power system model.
NASA Astrophysics Data System (ADS)
Sahoo, Sasmita; Jha, Madan K.
2017-12-01
Process-based groundwater models are useful to understand complex aquifer systems and make predictions about their response to hydrological changes. A conceptual model for evaluating responses to environmental changes is presented, considering the hydrogeologic framework, flow processes, aquifer hydraulic properties, boundary conditions, and sources and sinks of the groundwater system. Based on this conceptual model, a quasi-three-dimensional transient groundwater flow model was designed using MODFLOW to simulate the groundwater system of Mahanadi River delta, eastern India. The model was constructed in the context of an upper unconfined aquifer and lower confined aquifer, separated by an aquitard. Hydraulic heads of 13 shallow wells and 11 deep wells were used to calibrate transient groundwater conditions during 1997-2006, followed by validation (2007-2011). The aquifer and aquitard hydraulic properties were obtained by pumping tests and were calibrated along with the rainfall recharge. The statistical and graphical performance indicators suggested a reasonably good simulation of groundwater flow over the study area. Sensitivity analysis revealed that groundwater level is most sensitive to the hydraulic conductivities of both the aquifers, followed by vertical hydraulic conductivity of the confining layer. The calibrated model was then employed to explore groundwater-flow dynamics in response to changes in pumping and recharge conditions. The simulation results indicate that pumping has a substantial effect on the confined aquifer flow regime as compared to the unconfined aquifer. The results and insights from this study have important implications for other regional groundwater modeling studies, especially in multi-layered aquifer systems.
Separation of distinct photoexcitation species in femtosecond transient absorption microscopy
Xiao, Kai; Ma, Ying -Zhong; Simpson, Mary Jane; ...
2016-02-03
Femtosecond transient absorption microscopy is a novel chemical imaging capability with simultaneous high spatial and temporal resolution. Although several powerful data analysis approaches have been developed and successfully applied to separate distinct chemical species in such images, the application of such analysis to distinguish different photoexcited species is rare. In this paper, we demonstrate a combined approach based on phasor and linear decomposition analysis on a microscopic level that allows us to separate the contributions of both the excitons and free charge carriers in the observed transient absorption response of a composite organometallic lead halide perovskite film. We found spatialmore » regions where the transient absorption response was predominately a result of excitons and others where it was predominately due to charge carriers, and regions consisting of signals from both contributors. Lastly, quantitative decomposition of the transient absorption response curves further enabled us to reveal the relative contribution of each photoexcitation to the measured response at spatially resolved locations in the film.« less
A study of the kinetic energy generation with general circulation models
NASA Technical Reports Server (NTRS)
Chen, T.-C.; Lee, Y.-H.
1983-01-01
The history data of winter simulation by the GLAS climate model and the NCAR community climate model are used to examine the generation of atmospheric kinetic energy. The contrast between the geographic distributions of the generation of kinetic energy and divergence of kinetic energy flux shows that kinetic energy is generated in the upstream side of jets, transported to the downstream side and destroyed there. The contributions from the time-mean and transient modes to the counterbalance between generation of kinetic energy and divergence of kinetic energy flux are also investigated. It is observed that the kinetic energy generated by the time-mean mode is essentially redistributed by the time-mean flow, while that generated by the transient flow is mainly responsible for the maintenance of the kinetic energy of the entire atmospheric flow.
NASA Astrophysics Data System (ADS)
Lundgren, P.; Poland, M. P.; Miklius, A.; Anderson, K. R.
2014-12-01
Interferometric synthetic aperture radar (InSAR) and continuous GPS observations at the summit of Kīlauea Volcano, Hawaíi, show spatially and temporally transient surface displacements in the months and weeks before the 5-9 March 2011 Kamoamoa fissure eruption. Interferograms computed from the Italian Space Agency's COSMO-SkyMed satellites and the German Aerospace Center's TerraSAR-X satellite show a distinctive triangular pattern of surface deformation that extends to the SE of Kīlauea Caldera starting approximately one month prior to the Kamoamoa eruption. GPS and electronic tilt meter time series for sites in the vicinity of this deformation show that this inflation transient is superimposed on the longer (~4-6 month) summit inflation. We examine and model the spatiotemporal evolution of the summit deformation. InSAR data from ascending and descending tracks are used to constrain models of the transient. To achieve low-levels of atmospheric phase noise required interferograms spanning four months prior to the eruption, thus involving multiple sources within the summit region (see figure). To solve for model parameters we use a Markov Chain Monte Carlo optimization approach. First, we model the co-eruption summit deflation to isolate the intra-caldera sources, consisting of a steeply dipping tensile dislocation (D) beneath the western edge of the caldera and a sub-horizontal, NE trending spheroidal pressure source (Y) in the center of the caldera at 1.5 km depth. We use these sources as starting models for the pre-eruption transient, which requires the addition of a sill (S) to explain the deformation that extends to the SE of the caldera. In a third step we add a simplified model for Kīlauea's rifts and basal detachment system to explain the coupled summit and south flank motion. Modeled at over 3 km beneath the surface, the transient sill source inflates over the month before the eruption and deflates during the four-day eruption. The sill runs parallel to and to the west of upper East Rift Zone (ERZ) seismicity, considered to delineate the primary magma conduit to the ERZ at 3 km depth. The deflation of the sill during the eruption fits with the current standard model for Kīlauea: response to the overall depressurization of the summit and ERZ conduit system due to the Kamoamoa dike intrusion and eruption.
Modeling landslide recurrence in Seattle, Washington, USA
Salciarini, Diana; Godt, Jonathan W.; Savage, William Z.; Baum, Rex L.; Conversini, Pietro
2008-01-01
To manage the hazard associated with shallow landslides, decision makers need an understanding of where and when landslides may occur. A variety of approaches have been used to estimate the hazard from shallow, rainfall-triggered landslides, such as empirical rainfall threshold methods or probabilistic methods based on historical records. The wide availability of Geographic Information Systems (GIS) and digital topographic data has led to the development of analytic methods for landslide hazard estimation that couple steady-state hydrological models with slope stability calculations. Because these methods typically neglect the transient effects of infiltration on slope stability, results cannot be linked with historical or forecasted rainfall sequences. Estimates of the frequency of conditions likely to cause landslides are critical for quantitative risk and hazard assessments. We present results to demonstrate how a transient infiltration model coupled with an infinite slope stability calculation may be used to assess shallow landslide frequency in the City of Seattle, Washington, USA. A module called CRF (Critical RainFall) for estimating deterministic rainfall thresholds has been integrated in the TRIGRS (Transient Rainfall Infiltration and Grid-based Slope-Stability) model that combines a transient, one-dimensional analytic solution for pore-pressure response to rainfall infiltration with an infinite slope stability calculation. Input data for the extended model include topographic slope, colluvial thickness, initial water-table depth, material properties, and rainfall durations. This approach is combined with a statistical treatment of rainfall using a GEV (General Extreme Value) probabilistic distribution to produce maps showing the shallow landslide recurrence induced, on a spatially distributed basis, as a function of rainfall duration and hillslope characteristics.
On-Die Sensors for Transient Events
NASA Astrophysics Data System (ADS)
Suchak, Mihir Vimal
Failures caused by transient electromagnetic events like Electrostatic Discharge (ESD) are a major concern for embedded systems. The component often failing is an integrated circuit (IC). Determining which IC is affected in a multi-device system is a challenging task. Debugging errors often requires sophisticated lab setups which require intentionally disturbing and probing various parts of the system which might not be easily accessible. Opening the system and adding probes may change its response to the transient event, which further compounds the problem. On-die transient event sensors were developed that require relatively little area on die, making them inexpensive, they consume negligible static current, and do not interfere with normal operation of the IC. These circuits can be used to determine the pin involved and the level of the event in the event of a transient event affecting the IC, thus allowing the user to debug system-level transient events without modifying the system. The circuit and detection scheme design has been completed and verified in simulations with Cadence Virtuoso environment. Simulations accounted for the impact of the ESD protection circuits, parasitics from the I/O pin, package and I/O ring, and included a model of an ESD gun to test the circuit's response to an ESD pulse as specified in IEC 61000-4-2. Multiple detection schemes are proposed. The final detection scheme consists of an event detector and a level sensor. The event detector latches on the presence of an event at a pad, to determine on which pin an event occurred. The level sensor generates current proportional to the level of the event. This current is converted to a voltage and digitized at the A/D converter to be read by the microprocessor. Detection scheme shows good performance in simulations when checked against process variations and different kind of events.
Analysis of shell-type structures subjected to time-dependent mechanical and thermal loading
NASA Technical Reports Server (NTRS)
Simitses, G. J.; Riff, R.
1988-01-01
This research is performed to develop a general mathematical model and solution methodologies for analyzing structural response of thin, metallic shell-type structures under large transient, cyclic or static thermomechanical loads. Among the system responses, which are associated with these load conditions, are thermal buckling, creep buckling, and ratcheting. Thus, geometric as well as material-type nonlinearities (of high order) can be anticipated and must be considered in the development of the mathematical model. Furthermore, this must also be accommodated in the solution procedures.
Analysis of shell-type structures subjected to time-dependent mechanical and thermal loading
NASA Technical Reports Server (NTRS)
Simitses, G. J.
1989-01-01
The objective is to develop a general mathematical model and solution methodologies for analyzing structural response of thin, metallic shell-type structures under large transient, cyclic, or static thermomechanical loads. Among the system responses, which are associated with these load conditions, are thermal buckling, creep buckling, and racheting. Thus, geometric as well as material-type nonlinearities (of high order) can be anticipated and must be considered in the development of the mathematical model. Furthermore, this must also be accommodated in the solution procedures.
Analysis of shell-type structures subjected to time-dependent mechanical and thermal loading
NASA Technical Reports Server (NTRS)
Simitses, G. J.; Riff, R.
1988-01-01
The objective of this research is to develop a general mathematical model and solution methodologies for analyzing structural response of thin, metallic shell-type structures under large transient, cyclic or static thermomechanical loads. Among the system responses, which are associated with these load conditions, are thermal buckling, creep buckling and racheting. Thus, geometric as well as material-type nonlinearities (of high order) can be anticipated and must be considered in the development of the mathematical model. Furthermore, this must also be accommodated in the solution procedures.
Dynamics at Intermediate Time Scales and Management of Ecological Populations
2017-05-10
thinking about the importance of transients is to recognize the importance of serial autocorrelation in time of forcing terms over realistic ecological time...rich areas helps produce divergent home range responses bet - ween individuals from difference age classes. This model has broad applications for
NASA Technical Reports Server (NTRS)
Tamma, Kumar K.; D'Costa, Joseph F.
1991-01-01
This paper describes the evaluation of mixed implicit-explicit finite element formulations for hyperbolic heat conduction problems involving non-Fourier effects. In particular, mixed implicit-explicit formulations employing the alpha method proposed by Hughes et al. (1987, 1990) are described for the numerical simulation of hyperbolic heat conduction models, which involves time-dependent relaxation effects. Existing analytical approaches for modeling/analysis of such models involve complex mathematical formulations for obtaining closed-form solutions, while in certain numerical formulations the difficulties include severe oscillatory solution behavior (which often disguises the true response) in the vicinity of the thermal disturbances, which propagate with finite velocities. In view of these factors, the alpha method is evaluated to assess the control of the amount of numerical dissipation for predicting the transient propagating thermal disturbances. Numerical test models are presented, and pertinent conclusions are drawn for the mixed-time integration simulation of hyperbolic heat conduction models involving non-Fourier effects.
TRACE Model for Simulation of Anticipated Transients Without Scram in a BWR
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cheng L. Y.; Baek J.; Cuadra,A.
2013-11-10
A TRACE model has been developed for using theTRACE/PARCS computational package [1, 2] to simulate anticipated transients without scram (ATWS) events in a boiling water reactor (BWR). The model represents a BWR/5 housed in a Mark II containment. The reactor and the balance of plant systems are modeled in sufficient detail to enable the evaluation of plant responses and theeffectiveness of automatic and operator actions tomitigate this beyond design basis accident.The TRACE model implements features thatfacilitate the simulation of ATWS events initiated by turbine trip and closure of the main steam isolation valves (MSIV). It also incorporates control logic tomore » initiate actions to mitigate the ATWS events, such as water levelcontrol, emergency depressurization, and injection of boron via the standby liquid control system (SLCS). Two different approaches have been used to model boron mixing in the lower plenum of the reactor vessel: modulate coolant flow in the lower plenum by a flow valve, and use control logic to modular.« less
Salmonella Fecal Shedding and Immune Responses are Dose- and Serotype- Dependent in Pigs
Ivanek, Renata; Österberg, Julia; Gautam, Raju; Sternberg Lewerin, Susanna
2012-01-01
Despite the public health importance of Salmonella infection in pigs, little is known about the associated dynamics of fecal shedding and immunity. In this study, we investigated the transitions of pigs through the states of Salmonella fecal shedding and immune response post-Salmonella inoculation as affected by the challenge dose and serotype. Continuous-time multistate Markov models were developed using published experimental data. The model for shedding had four transient states, of which two were shedding (continuous and intermittent shedding) and two non-shedding (latency and intermittent non-shedding), and one absorbing state representing permanent cessation of shedding. The immune response model had two transient states representing responses below and above the seroconversion level. The effects of two doses [low (0.65×106 CFU/pig) and high (0.65×109 CFU/pig)] and four serotypes (Salmonella Yoruba, Salmonella Cubana, Salmonella Typhimurium, and Salmonella Derby) on the models' transition intensities were evaluated using a proportional intensities model. Results indicated statistically significant effects of the challenge dose and serotype on the dynamics of shedding and immune response. The time spent in the specific states was also estimated. Continuous shedding was on average 10–26 days longer, while intermittent non-shedding was 2–4 days shorter, in pigs challenged with the high compared to low dose. Interestingly, among pigs challenged with the high dose, the continuous and intermittent shedding states were on average up to 10–17 and 3–4 days longer, respectively, in pigs infected with S. Cubana compared to the other three serotypes. Pigs challenged with the high dose of S. Typhimurium or S. Derby seroconverted on average up to 8–11 days faster compared to the low dose. These findings highlight that Salmonella fecal shedding and immune response following Salmonella challenge are dose- and serotype-dependent and that the detection of specific Salmonella strains and immune responses in pigs are time-sensitive. PMID:22523553
NASA Technical Reports Server (NTRS)
Branscome, Lee E.; Gutowski, William J., Jr.
1991-01-01
Atmospheric transient eddies contribute significantly to mid-latitude energy and water vapor transports. Changes in the global climate, as induced by greenhouse enhancement, will likely alter transient eddy behavior. Unraveling all the feedbacks that occur in general circulation models (GCMs) can be difficult. The transient eddies are isolated from the feedbacks and are focused on the response of the eddies to zonal-mean climate changes that result from CO2-doubling. Using a primitive-equation spectral model, the impact of climate change on the life cycles of transient eddies is examined. Transient eddy behavior in experiments is compared with initial conditions that are given by the zonal-mean climates of the GCMs with current and doubled amounts of CO2. The smaller meridional temperature gradient in a doubled CO2 climate leads to a reduction in eddy kinetic energy, especially in the subtropics. The decrease in subtropical eddy energy is related to a substantial reduction in equatorward flux of eddy activity during the latter part of the life cycle. The reduction in equatorward energy flux alters the moisture cycle. Eddy meridional transport of water vapor is shifted slightly poleward and subtropical precipitation is reduced. The water vapor transport exhibits a relatively small change in magnitude, compared to changes in eddy energy, due to the compensating effect of higher specific humidity in the doubled-CO2 climate. An increase in high-latitude precipitation is related to the poleward shift in eddy water vapor flux. Surface evaporation amplifies climatic changes in water vapor transport and precipitation in the experiments.
NASA Technical Reports Server (NTRS)
Lyle, Karen H.; Vassilakos, Gregory J.
2015-01-01
This report summarizes the initial modeling of the global response of the Bigelow Expandable Activity Module (BEAM) to micrometeorite and orbital debris(MMOD) impacts using a structural, nonlinear, transient dynamic, finite element code. These models complement the on-orbit deployment of the Distributed Impact Detection System (DIDS) to support structural health monitoring studies. Two global models were developed. The first focused exclusively on impacts on the soft-goods (fabric-envelop) portion of BEAM. The second incorporates the bulkhead to support understanding of bulkhead impacts. These models were exercised for random impact locations and responses monitored at the on-orbit sensor locations. The report concludes with areas for future study.
Ou, Yvonne; Jo, Rebecca E; Ullian, Erik M; Wong, Rachel O L; Della Santina, Luca
2016-08-31
Key issues concerning ganglion cell type-specific loss and synaptic changes in animal models of experimental glaucoma remain highly debated. Importantly, changes in the structure and function of various RGC types that occur early, within 14 d after acute, transient intraocular pressure elevation, have not been previously assessed. Using biolistic transfection of individual RGCs and multielectrode array recordings to measure light responses in mice, we examined the effects of laser-induced ocular hypertension on the structure and function of a subset of RGCs. Among the α-like RGCs studied, αOFF-transient RGCs exhibited higher rates of cell death, with corresponding reductions in dendritic area, dendritic complexity, and synapse density. Functionally, OFF-transient RGCs displayed decreases in spontaneous activity and receptive field size. In contrast, neither αOFF-sustained nor αON-sustained RGCs displayed decreases in light responses, although they did exhibit a decrease in excitatory postsynaptic sites, suggesting that synapse loss may be one of the earliest signs of degeneration. Interestingly, presynaptic ribbon density decreased to a greater degree in the OFF sublamina of the inner plexiform layer, corroborating the hypothesis that RGCs with dendrites stratifying in the OFF sublamina may be damaged early. Indeed, OFF arbors of ON-OFF RGCs lose complexity more rapidly than ON arbors. Our results reveal type-specific differences in RGC responses to injury with a selective vulnerability of αOFF-transient RGCs, and furthermore, an increased susceptibility of synapses in the OFF sublamina. The selective vulnerability of specific RGC types offers new avenues for the design of more sensitive functional tests and targeted neuroprotection. Conflicting reports regarding the selective vulnerability of specific retinal ganglion cell (RGC) types in glaucoma exist. We examine, for the first time, the effects of transient intraocular pressure elevation on the structure and function of various RGC types. Among the α-like RGCs studied, αOFF-transient RGCs are the most vulnerable to transient transient intraocular pressure elevation as measured by rates of cell death, morphologic alterations in dendrites and synapses, and physiological dysfunction. Specifically, we found that presynaptic ribbon density decreased to a greater degree in the OFF sublamina of the inner plexiform layer. Our results suggest selective vulnerability both of specific types of RGCs and of specific inner plexiform layer sublaminae, opening new avenues for identifying novel diagnostic and treatment targets in glaucoma. Copyright © 2016 the authors 0270-6474/16/369240-13$15.00/0.
The effects of transient rheology on the interpretation of lower mantle viscosity
NASA Technical Reports Server (NTRS)
Sabadini, R.; Yuen, D. A.; Gasperini, P.
1985-01-01
The role played by transient rheology in the interpretation of mantle viscosity is reexamined. The investigation has been carried out by comparing the amplitude responses with the data of secular variation of J(2), the relative sea-level histories at sites well within the ice margins and at the ice margin like the city of Boston. A linear Burgers body rheology has been assumed in ther lower mantle. The data near the edge of the ice load proves most sensitive to the transient viscosity structure. The non-monotonic behavior of sea-level data near Boston can be explained both by a steady-state lower mantle viscosity of 10 to the 22nd P with a thick lithosphere and by a transient lower mantle rheology but with a thin lithosphere. The long-term viscosity of the lower mantle in this second model has a steady-state value of around 5 x 10 to the 23rd P.
Nonlinear interaction between underwater explosion bubble and structure based on fully coupled model
NASA Astrophysics Data System (ADS)
Zhang, A. M.; Wu, W. B.; Liu, Y. L.; Wang, Q. X.
2017-08-01
The interaction between an underwater explosion bubble and an elastic-plastic structure is a complex transient process, accompanying violent bubble collapsing, jet impact, penetration through the bubble, and large structural deformation. In the present study, the bubble dynamics are modeled using the boundary element method and the nonlinear transient structural response is modeled using the explicit finite element method. A new fully coupled 3D model is established through coupling the equations for the state variables of the fluid and structure and solving them as a set of coupled linear algebra equations. Based on the acceleration potential theory, the mutual dependence between the hydrodynamic load and the structural motion is decoupled. The pressure distribution in the flow field is calculated with the Bernoulli equation, where the partial derivative of the velocity potential in time is calculated using the boundary integral method to avoid numerical instabilities. To validate the present fully coupled model, the experiments of small-scale underwater explosion near a stiffened plate are carried out. High-speed imaging is used to capture the bubble behaviors and strain gauges are used to measure the strain response. The numerical results correspond well with the experimental data, in terms of bubble shapes and structural strain response. By both the loosely coupled model and the fully coupled model, the interaction between a bubble and a hollow spherical shell is studied. The bubble patterns vary with different parameters. When the fully coupled model and the loosely coupled model are advanced with the same time step, the error caused by the loosely coupled model becomes larger with the coupling effect becoming stronger. The fully coupled model is more stable than the loosely coupled model. Besides, the influences of the internal fluid on the dynamic response of the spherical shell are studied. At last, the case that the bubble interacts with an air-backed stiffened plate is simulated. The associated interesting physical phenomenon is obtained and expounded.
NASA Astrophysics Data System (ADS)
Piggott, Alfred J., III
With increased public interest in protecting the environment, scientists and engineers aim to improve energy conversion efficiency. Thermoelectrics offer many advantages as thermal management technology. When compared to vapor compression refrigeration, above approximately 200 to 600 watts, cost in dollars per watt as well as COP are not advantageous for thermoelectrics. The goal of this work was to determine if optimized pulse supercooling operation could improve cooling capacity or efficiency of a thermoelectric device. The basis of this research is a thermal-electrical analogy based modeling study using SPICE. Two models were developed. The first model, a standalone thermocouple with no attached mass to be cooled. The second, a system that includes a module attached to a heat generating mass. With the thermocouple study, a new approach of generating response surfaces with characteristic parameters was applied. The current pulse height and pulse on-time was identified for maximizing Net Transient Advantage, a newly defined metric. The corresponding pulse height and pulse on-time was utilized for the system model. Along with the traditional steady state starting current of Imax, Iopt was employed. The pulse shape was an isosceles triangle. For the system model, metrics new to pulse cooling were Qc, power consumption and COP. The effects of optimized current pulses were studied by changing system variables. Further studies explored time spacing between pulses and temperature distribution in the thermoelement. It was found net Q c over an entire pulse event can be improved over Imax steady operation but not over steady I opt operation. Qc can be improved over Iopt operation but only during the early part of the pulse event. COP is reduced in transient pulse operation due to the different time constants of Qc and Pin. In some cases lower performance interface materials allow more Qc and better COP during transient operation than higher performance interface materials. Important future work might look at developing innovative ways of biasing Joule heat to Th..
Optimal plant nitrogen use improves model representation of vegetation response to elevated CO2
NASA Astrophysics Data System (ADS)
Caldararu, Silvia; Kern, Melanie; Engel, Jan; Zaehle, Sönke
2017-04-01
Existing global vegetation models often cannot accurately represent observed ecosystem behaviour under transient conditions such as elevated atmospheric CO2, a problem that can be attributed to an inflexibility in model representation of plant responses. Plant optimality concepts have been proposed as a solution to this problem as they offer a way to represent plastic plant responses in complex models. Here we present a novel, next generation vegetation model which includes optimal nitrogen allocation to and within the canopy as well as optimal biomass allocation between above- and belowground components in response to nutrient and water availability. The underlying hypothesis is that plants adjust their use of nitrogen in response to environmental conditions and nutrient availability in order to maximise biomass growth. We show that for two FACE (Free Air CO2 enrichment) experiments, the Duke forest and Oak Ridge forest sites, the model can better predict vegetation responses over the duration of the experiment when optimal processes are included. Specifically, under elevated CO2 conditions, the model predicts a lower optimal leaf N concentration as well as increased biomass allocation to fine roots, which, combined with a redistribution of leaf N between the Rubisco and chlorophyll components, leads to a continued NPP response under high CO2, where models with a fixed canopy stoichiometry predict a quick onset of N limitation.Existing global vegetation models often cannot accurately represent observed ecosystem behaviour under transient conditions such as elevated atmospheric CO2, a problem that can be attributed to an inflexibility in model representation of plant responses. Plant optimality concepts have been proposed as a solution to this problem as they offer a way to represent plastic plant responses in complex models. Here we present a novel, next generation vegetation model which includes optimal nitrogen allocation to and within the canopy as well as optimal biomass allocation between above- and belowground components in response to nutrient and water availability. The underlying hypothesis is that plants adjust their use of nitrogen in response to environmental conditions and nutrient availability in order to maximise biomass growth. We show that for two FACE (Free Air CO2 enrichment) experiments, the Duke forest and Oak Ridge forest sites, the model can better predict vegetation responses over the duration of the experiment when optimal processes are included. Specifically, under elevated CO2 conditions, the model predicts a lower optimal leaf N concentration as well as increased biomass allocation to fine roots, which, combined with a redistribution of leaf N between the Rubisco and chlorophyll components, leads to a continued NPP response under high CO2, where models with a fixed canopy stoichiometry predict a quick onset of N limitation.
Hydro-mechanical mechanism and thresholds of rainfall-induced unsaturated landslides
NASA Astrophysics Data System (ADS)
Yang, Zongji; Lei, Xiaoqin; Huang, Dong; Qiao, Jianping
2017-04-01
The devastating Ms 8 Wenchuan earthquake in 2008 created the greatest number of co-seismic mountain hazards ever recorded in China. However, the dynamics of rainfall induced mass remobilization and transport deposits after giant earthquake are not fully understood. Moreover, rainfall intensity and duration (I-D) methods are the predominant early warning indicators of rainfall-induced landslides in post-earthquake region, which are a convenient and straight-forward way to predict the hazards. However, the rainfall-based criteria and thresholds are generally empirical and based on statistical analysis,consequently, they ignore the failure mechanisms of the landslides. This study examines the mechanism and hydro-mechanical behavior and thresholds of these unsaturated deposits under the influence of rainfall. To accomplish this, in situ experiments were performed in an instrumented landslide deposit, The field experimental tests were conducted on a natural co-seismic fractured slope to 1) simulate rainfall-induced shallow failures in the depression channels of a debris flow catchment in an earthquake-affected region, 2)explore the mechanisms and transient processes associated with hydro-mechanical parameter variations in response to the infiltration of rainfall, and 3) identify the hydrologic parameter thresholds and critical criteria of gravitational erosion in areas prone to mass remobilization as a source of debris flows. These experiments provided instrumental evidence and directly proved that post-earthquake rainfall-induced mass remobilization occurred under unsaturated conditions in response to transient rainfall infiltration, and revealed the presence of transient processes and the dominance of preferential flow paths during rainfall infiltration. A hydro-mechanical method was adopted for the transient hydrologic process modelling and unsaturated slope stability analysis. and the slope failures during the experimental test were reproduced by the model, indicating that the decrease in matrix suction and increase in moisture content in response to rainfall infiltration contributed greatly to post-earthquake shallow mass movement. Thus, a threshold model for the initiation of mass remobilization is proposed based on correlations between slope stability and volumetric water content and matrix suction As a complement to rainfall-based early warning strategies, the water content and suction threshold models based on the water infiltration induced slope failure mechanism. the proposed method are expected to improve the accuracy of prediction and early warnings of post-earthquake mountain hazards
Thermohydrodynamic analysis of cryogenic liquid turbulent flow fluid film bearings, phase 2
NASA Technical Reports Server (NTRS)
Sanandres, Luis
1994-01-01
The Phase 2 (1994) Annual Progress Report presents two major report sections describing the thermal analysis of tilting- and flexure-pad hybrid bearings, and the unsteady flow and transient response of a point mass rotor supported on fluid film bearings. A literature review on the subject of two-phase flow in fluid film bearings and part of the proposed work for 1995 are also included. The programs delivered at the end of 1994 are named hydroflext and hydrotran. Both codes are fully compatible with the hydrosealt (1993) program. The new programs retain the same calculating options of hydrosealt plus the added bearing geometries, and unsteady flow and transient forced response. Refer to the hydroflext & hydrotran User's Manual and Tutorial for basic information on the analysis and instructions to run the programs. The Examples Handbook contains the test bearing cases along with comparisons with experimental data or published analytical values. The following major tasks were completed in 1994 (Phase 2): (1) extension of the thermohydrodynamic analysis and development of computer program hydroflext to model various bearing geometries, namely, tilting-pad hydrodynamic journal bearings, flexure-pad cylindrical bearings (hydrostatic and hydrodynamic), and cylindrical pad bearings with a simple elastic matrix (ideal foil bearings); (2) improved thermal model including radial heat transfer through the bearing stator; (3) calculation of the unsteady bulk-flow field in fluid film bearings and the transient response of a point mass rotor supported on bearings; and (4) a literature review on the subject of two-phase flows and homogeneous-mixture flows in thin-film geometries.
Martinez-Sanchez, Mariana Esther; Mendoza, Luis; Villarreal, Carlos; Alvarez-Buylla, Elena R.
2015-01-01
CD4+ T cells orchestrate the adaptive immune response in vertebrates. While both experimental and modeling work has been conducted to understand the molecular genetic mechanisms involved in CD4+ T cell responses and fate attainment, the dynamic role of intrinsic (produced by CD4+ T lymphocytes) versus extrinsic (produced by other cells) components remains unclear, and the mechanistic and dynamic understanding of the plastic responses of these cells remains incomplete. In this work, we studied a regulatory network for the core transcription factors involved in CD4+ T cell-fate attainment. We first show that this core is not sufficient to recover common CD4+ T phenotypes. We thus postulate a minimal Boolean regulatory network model derived from a larger and more comprehensive network that is based on experimental data. The minimal network integrates transcriptional regulation, signaling pathways and the micro-environment. This network model recovers reported configurations of most of the characterized cell types (Th0, Th1, Th2, Th17, Tfh, Th9, iTreg, and Foxp3-independent T regulatory cells). This transcriptional-signaling regulatory network is robust and recovers mutant configurations that have been reported experimentally. Additionally, this model recovers many of the plasticity patterns documented for different T CD4+ cell types, as summarized in a cell-fate map. We tested the effects of various micro-environments and transient perturbations on such transitions among CD4+ T cell types. Interestingly, most cell-fate transitions were induced by transient activations, with the opposite behavior associated with transient inhibitions. Finally, we used a novel methodology was used to establish that T-bet, TGF-β and suppressors of cytokine signaling proteins are keys to recovering observed CD4+ T cell plastic responses. In conclusion, the observed CD4+ T cell-types and transition patterns emerge from the feedback between the intrinsic or intracellular regulatory core and the micro-environment. We discuss the broader use of this approach for other plastic systems and possible therapeutic interventions. PMID:26090929
Strychnine blocks transient but not sustained inhibition in mudpuppy retinal ganglion cells.
Belgum, J H; Dvorak, D R; McReynolds, J S
1984-01-01
Transient and sustained inhibitory synaptic inputs to on-centre, off-centre, and on-off ganglion cells in the mudpuppy retina were studied using intracellular recording in the superfused eye-cup preparation. When chemical transmission was blocked with 4 mM-Co2+, application of either glycine or gamma-aminobutyric acid (GABA) caused a hyperpolarization and conductance increase in all ganglion cells. For both amino acids, the responses were dose dependent in the range 0.05-10 mM, with a half-maximal response at about 0.7 mM. Glycine and GABA sensitivities were very similar in all three types of ganglion cells. The response to applied glycine was selectively antagonized by 10(-5) M-strychnine and the response to applied GABA was selectively antagonized by 10(-5) M-picrotoxin. In all ganglion cells, 10(-5) M-strychnine eliminated the transient inhibitory events which occur at the onset and termination of a light stimulus. The block of transient inhibition was associated with a relative depolarization of membrane potential and decrease in conductance at these times. Strychnine had no effect on membrane potential or conductance in darkness or during sustained inhibitory responses to light. Picrotoxin (10(-5) M) did not block transient inhibitory events in any ganglion cells, but did affect other components of their responses. The results suggest that in all three classes of ganglion cells transient inhibition, but not sustained inhibition, may be mediated by glycine or a closely related substance. PMID:6481635
Adeeb A. Rahman; Thomas J. Urbanik; Mustafa Mahamid
2003-01-01
Collapse of fiberboard packaging boxes, in the shipping industry, due to rise in humidity conditions is common and very costly. A 3D FE nonlinear model is developed to predict the moisture flow throughout a corrugated packaging fiberboard sandwich structure. The model predicts how the moisture diffusion will permeate through the layers of a fiberboard (medium and...
Modeling of ESD events from polymeric surfaces
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pfeifer, Kent Bryant
2014-03-01
Transient electrostatic discharge (ESD) events are studied to assemble a predictive model of discharge from polymer surfaces. An analog circuit simulation is produced and its response is compared to various literature sources to explore its capabilities and limitations. Results suggest that polymer ESD events can be predicted to within an order of magnitude. These results compare well to empirical findings from other sources having similar reproducibility.
Posttest data analysis of FIST experimental TRAC-BD1/MOD1 power transient experiment
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wheatley, P.D.; Wagner, K.C.
The FIST power transient test 6PMC2 was analyzed to further the understanding of the FIST facility and provide an assessment of TRAC-BD1/MOD1. FIST power transient 6PMC2 investigated the thermal-hydraulic response following inadvertent closure of the main steam isolation valve and the subsequent failure of the reactor to scram. Failure of the high pressure core spray system was also assumed, resulting in only the reactor core isolation cooling flow for inventory makeup during the transient. The experiment was a sensitivity study with relatively high core power and low makeup rates. This study provides one of the first opportunities to assess TRAC-BD1/MOD1more » under power transient and natural circulation conditions with data from a facility with prototypical BWR geometry. The power transient test was analyzed with emphasis on the following phenomena: (a) the system pressure response, (b) the natural circulation flows and rates, and (c) the heater rod cladding temperature response. Based on the results of this study, TRAC-BD1/MOD1 can be expected to calculate the thermal-hydraulic behavior of a BWR during a power transient.« less
Vaas, Markus; Enzmann, Gaby; Perinat, Therese; Siler, Ulrich; Reichenbach, Janine; Licha, Kai; Kipar, Anja; Rudin, Markus; Engelhardt, Britta; Klohs, Jan
2017-08-01
Near-infrared fluorescence (NIRF) imaging enables non-invasive monitoring of molecular and cellular processes in live animals. Here we demonstrate the suitability of NIRF imaging to investigate the neutrophil response in the brain after transient middle cerebral artery occlusion (tMCAO). We established procedures for ex vivo fluorescent labelling of neutrophils without affecting their activation status. Adoptive transfer of labelled neutrophils in C57BL/6 mice before surgery resulted in higher fluorescence intensities over the ischaemic hemisphere in tMCAO mice with NIRF imaging when compared with controls, corroborated by ex vivo detection of labelled neutrophils using fluorescence microscopy. NIRF imaging showed that neutrophils started to accumulate immediately after tMCAO, peaking at 18 h, and were still visible until 48 h after reperfusion. Our data revealed accumulation of neutrophils also in extracranial tissue, indicating damage in the external carotid artery territory in the tMCAO model. Antibody-mediated inhibition of α4-integrins did reduce fluorescence signals at 18 and 24, but not at 48 h after reperfusion, compared with control treatment animals. Antibody treatment reduced cerebral lesion volumes by 19%. In conclusion, the non-invasive nature of NIRF imaging allows studying the dynamics of neutrophil recruitment and its modulation by targeted interventions in the mouse brain after transient experimental cerebral ischaemia.
Vaas, Markus; Enzmann, Gaby; Perinat, Therese; Siler, Ulrich; Reichenbach, Janine; Licha, Kai; Kipar, Anja; Rudin, Markus; Engelhardt, Britta
2016-01-01
Near-infrared fluorescence (NIRF) imaging enables non-invasive monitoring of molecular and cellular processes in live animals. Here we demonstrate the suitability of NIRF imaging to investigate the neutrophil response in the brain after transient middle cerebral artery occlusion (tMCAO). We established procedures for ex vivo fluorescent labelling of neutrophils without affecting their activation status. Adoptive transfer of labelled neutrophils in C57BL/6 mice before surgery resulted in higher fluorescence intensities over the ischaemic hemisphere in tMCAO mice with NIRF imaging when compared with controls, corroborated by ex vivo detection of labelled neutrophils using fluorescence microscopy. NIRF imaging showed that neutrophils started to accumulate immediately after tMCAO, peaking at 18 h, and were still visible until 48 h after reperfusion. Our data revealed accumulation of neutrophils also in extracranial tissue, indicating damage in the external carotid artery territory in the tMCAO model. Antibody-mediated inhibition of α4-integrins did reduce fluorescence signals at 18 and 24, but not at 48 h after reperfusion, compared with control treatment animals. Antibody treatment reduced cerebral lesion volumes by 19%. In conclusion, the non-invasive nature of NIRF imaging allows studying the dynamics of neutrophil recruitment and its modulation by targeted interventions in the mouse brain after transient experimental cerebral ischaemia. PMID:27789786
PID Controller Settings Based on a Transient Response Experiment
ERIC Educational Resources Information Center
Silva, Carlos M.; Lito, Patricia F.; Neves, Patricia S.; Da Silva, Francisco A.
2008-01-01
An experimental work on controller tuning for chemical engineering undergraduate students is proposed using a small heat exchange unit. Based upon process reaction curves in open-loop configuration, system gain and time constant are determined for first order model with time delay with excellent accuracy. Afterwards students calculate PID…
NASA Technical Reports Server (NTRS)
Eggleston, John M; Mathews, Charles W
1954-01-01
In the process of analyzing the longitudinal frequency-response characteristics of aircraft, information on some of the methods of analysis has been obtained by the Langley Aeronautical Laboratory of the National Advisory Committee for Aeronautics. In the investigation of these methods, the practical applications and limitations were stressed. In general, the methods considered may be classed as: (1) analysis of sinusoidal response, (2) analysis of transient response as to harmonic content through determination of the Fourier integral by manual or machine methods, and (3) analysis of the transient through the use of least-squares solutions of the coefficients of an assumed equation for either the transient time response or frequency response (sometimes referred to as curve-fitting methods). (author)
Kim, Kyung Man; Baratta, Michael V; Yang, Aimei; Lee, Doheon; Boyden, Edward S; Fiorillo, Christopher D
2012-01-01
Activation of dopamine receptors in forebrain regions, for minutes or longer, is known to be sufficient for positive reinforcement of stimuli and actions. However, the firing rate of dopamine neurons is increased for only about 200 milliseconds following natural reward events that are better than expected, a response which has been described as a "reward prediction error" (RPE). Although RPE drives reinforcement learning (RL) in computational models, it has not been possible to directly test whether the transient dopamine signal actually drives RL. Here we have performed optical stimulation of genetically targeted ventral tegmental area (VTA) dopamine neurons expressing Channelrhodopsin-2 (ChR2) in mice. We mimicked the transient activation of dopamine neurons that occurs in response to natural reward by applying a light pulse of 200 ms in VTA. When a single light pulse followed each self-initiated nose poke, it was sufficient in itself to cause operant reinforcement. Furthermore, when optical stimulation was delivered in separate sessions according to a predetermined pattern, it increased locomotion and contralateral rotations, behaviors that are known to result from activation of dopamine neurons. All three of the optically induced operant and locomotor behaviors were tightly correlated with the number of VTA dopamine neurons that expressed ChR2, providing additional evidence that the behavioral responses were caused by activation of dopamine neurons. These results provide strong evidence that the transient activation of dopamine neurons provides a functional reward signal that drives learning, in support of RL theories of dopamine function.
Analyzing neuronal networks using discrete-time dynamics
NASA Astrophysics Data System (ADS)
Ahn, Sungwoo; Smith, Brian H.; Borisyuk, Alla; Terman, David
2010-05-01
We develop mathematical techniques for analyzing detailed Hodgkin-Huxley like models for excitatory-inhibitory neuronal networks. Our strategy for studying a given network is to first reduce it to a discrete-time dynamical system. The discrete model is considerably easier to analyze, both mathematically and computationally, and parameters in the discrete model correspond directly to parameters in the original system of differential equations. While these networks arise in many important applications, a primary focus of this paper is to better understand mechanisms that underlie temporally dynamic responses in early processing of olfactory sensory information. The models presented here exhibit several properties that have been described for olfactory codes in an insect’s Antennal Lobe. These include transient patterns of synchronization and decorrelation of sensory inputs. By reducing the model to a discrete system, we are able to systematically study how properties of the dynamics, including the complex structure of the transients and attractors, depend on factors related to connectivity and the intrinsic and synaptic properties of cells within the network.
Ohashi, Nobuko; Uta, Daisuke; Sasaki, Mika; Ohashi, Masayuki; Kamiya, Yoshinori; Kohno, Tatsuro
2017-08-01
The widely used analgesic acetaminophen is metabolized to N-acylphenolamine, which induces analgesia by acting directly on transient receptor potential vanilloid 1 or cannabinoid 1 receptors in the brain. Although these receptors are also abundant in the spinal cord, no previous studies have reported analgesic effects of acetaminophen or N-acylphenolamine mediated by the spinal cord dorsal horn. We hypothesized that clinical doses of acetaminophen induce analgesia via these spinal mechanisms. We assessed our hypothesis in a rat model using behavioral measures. We also used in vivo and in vitro whole cell patch-clamp recordings of dorsal horn neurons to assess excitatory synaptic transmission. Intravenous acetaminophen decreased peripheral pinch-induced excitatory responses in the dorsal horn (53.1 ± 20.7% of control; n = 10; P < 0.01), while direct application of acetaminophen to the dorsal horn did not reduce these responses. Direct application of N-acylphenolamine decreased the amplitudes of monosynaptic excitatory postsynaptic currents evoked by C-fiber stimulation (control, 462.5 ± 197.5 pA; N-acylphenolamine, 272.5 ± 134.5 pA; n = 10; P = 0.022) but not those evoked by stimulation of Aδ-fibers. These phenomena were mediated by transient receptor potential vanilloid 1 receptors, but not cannabinoid 1 receptors. The analgesic effects of acetaminophen and N-acylphenolamine were stronger in rats experiencing an inflammatory pain model compared to naïve rats. Our results suggest that the acetaminophen metabolite N-acylphenolamine induces analgesia directly via transient receptor potential vanilloid 1 receptors expressed on central terminals of C-fibers in the spinal dorsal horn and leads to conduction block, shunt currents, and desensitization of these fibers.
Exact finite element method analysis of viscoelastic tapered structures to transient loads
NASA Technical Reports Server (NTRS)
Spyrakos, Constantine Chris
1987-01-01
A general method is presented for determining the dynamic torsional/axial response of linear structures composed of either tapered bars or shafts to transient excitations. The method consists of formulating and solving the dynamic problem in the Laplace transform domain by the finite element method and obtaining the response by a numerical inversion of the transformed solution. The derivation of the torsional and axial stiffness matrices is based on the exact solution of the transformed governing equation of motion, and it consequently leads to the exact solution of the problem. The solution permits treatment of the most practical cases of linear tapered bars and shafts, and employs modeling of structures with only one element per member which reduces the number of degrees of freedom involved. The effects of external viscous or internal viscoelastic damping are also taken into account.
Wave Response during Hydrostatic and Geostrophic Adjustment. Part I: Transient Dynamics.
NASA Astrophysics Data System (ADS)
Chagnon, Jeffrey M.; Bannon, Peter R.
2005-05-01
The adjustment of a compressible, stably stratified atmosphere to sources of hydrostatic and geostrophic imbalance is investigated using a linear model. Imbalance is produced by prescribed, time-dependent injections of mass, heat, or momentum that model those processes considered “external” to the scales of motion on which the linearization and other model assumptions are justifiable. Solutions are demonstrated in response to a localized warming characteristic of small isolated clouds, larger thunderstorms, and convective systems.For a semi-infinite atmosphere, solutions consist of a set of vertical modes of continuously varying wavenumber, each of which contains time dependencies classified as steady, acoustic wave, and buoyancy wave contributions. Additionally, a rigid lower-boundary condition implies the existence of a discrete mode—the Lamb mode— containing only a steady and acoustic wave contribution. The forced solutions are generalized in terms of a temporal Green's function, which represents the response to an instantaneous injection.The response to an instantaneous warming with geometry representative of a small, isolated cloud takes place in two stages. Within the first few minutes, acoustic and Lamb waves accomplish an expansion of the heated region. Within the first quarter-hour, nonhydrostatic buoyancy waves accomplish an upward displacement inside of the heated region with inflow below, outflow above, and weak subsidence on the periphery—all mainly accomplished by the lowest vertical wavenumber modes, which have the largest horizontal group speed. More complicated transient patterns of inflow aloft and outflow along the lower boundary are accomplished by higher vertical wavenumber modes. Among these is an outwardly propagating rotor along the lower boundary that effectively displaces the low-level inflow upward and outward.A warming of 20 min duration with geometry representative of a large thunderstorm generates only a weak acoustic response in the horizontal by the Lamb waves. The amplitude of this signal increases during the onset of the heating and decreases as the heating is turned off. The lowest vertical wavenumber buoyancy waves still dominate the horizontal adjustment, and the horizontal scale of displacements is increased by an order of magnitude. Within a few hours the transient motions remove the perturbations and an approximately trivial balanced state is established.A warming of 2 h duration with geometry representative of a large convective system generates a weak but discernible Lamb wave signal. The response to the conglomerate system is mainly hydrostatic. After several hours, the only signal in the vicinity of the heated region is that of inertia-gravity waves oscillating about a nontrivial hydrostatic and geostrophic state.This paper is the first of two parts treating the transient dynamics of hydrostatic and geostrophic adjustment. Part II examines the potential vorticity conservation and the partitioning of total energy.
NASA Astrophysics Data System (ADS)
Legro, J. R.; Abi-Samra, N. C.; Tesche, F. M.
1985-05-01
In addition to the initial transients designated as fast transient high-altitude EMP (HEMP) and intermediate time EMP, electromagnetic signals are also perceived at times from seconds to hundreds of seconds after a high-altitude nuclear burst. This signal was defined by the term magnetohydrodynamic-electromagnetic pulse (MHD-EMP). The MHD-EMP phenomena was detected in actual weapon tests and predicted from theoretical models. A preliminary research effort to investigate the nature and coupling of the MHD-EMP environments to electric power systems documented the construction of approximate system response network models, and the development of a unified methodology to assess equipment and systematic vulnerability are defined. The MHD-EMP environment is compared to a qualitatively similar natural event, the electromagnetic environment produced by geomagnetic storms.
NASA Astrophysics Data System (ADS)
Federici, Gianfranco; Raffray, A. René
1997-04-01
The transient thermal model RACLETTE (acronym of Rate Analysis Code for pLasma Energy Transfer Transient Evaluation) described in part I of this paper is applied here to analyse the heat transfer and erosion effects of various slow (100 ms-10 s) high power energy transients on the actively cooled plasma facing components (PFCs) of the International Thermonuclear Experimental Reactor (ITER). These have a strong bearing on the PFC design and need careful analysis. The relevant parameters affecting the heat transfer during the plasma excursions are established. The temperature variation with time and space is evaluated together with the extent of vaporisation and melting (the latter only for metals) for the different candidate armour materials considered for the design (i.e., Be for the primary first wall, Be and CFCs for the limiter, Be, W, and CFCs for the divertor plates) and including for certain cases low-density vapour shielding effects. The critical heat flux, the change of the coolant parameters and the possible severe degradation of the coolant heat removal capability that could result under certain conditions during these transients, for example for the limiter, are also evaluated. Based on the results, the design implications on the heat removal performance and erosion damage of the variuos ITER PFCs are critically discussed and some recommendations are made for the selection of the most adequate protection materials and optimum armour thickness.
An Improved Dynamic Model for the Respiratory Response to Exercise
Serna, Leidy Y.; Mañanas, Miguel A.; Hernández, Alher M.; Rabinovich, Roberto A.
2018-01-01
Respiratory system modeling has been extensively studied in steady-state conditions to simulate sleep disorders, to predict its behavior under ventilatory diseases or stimuli and to simulate its interaction with mechanical ventilation. Nevertheless, the studies focused on the instantaneous response are limited, which restricts its application in clinical practice. The aim of this study is double: firstly, to analyze both dynamic and static responses of two known respiratory models under exercise stimuli by using an incremental exercise stimulus sequence (to analyze the model responses when step inputs are applied) and experimental data (to assess prediction capability of each model). Secondly, to propose changes in the models' structures to improve their transient and stationary responses. The versatility of the resulting model vs. the other two is shown according to the ability to simulate ventilatory stimuli, like exercise, with a proper regulation of the arterial blood gases, suitable constant times and a better adjustment to experimental data. The proposed model adjusts the breathing pattern every respiratory cycle using an optimization criterion based on minimization of work of breathing through regulation of respiratory frequency. PMID:29467674
NASA Technical Reports Server (NTRS)
Spilker, R. L.; Witmer, E. A.; French, S. E.; Rodal, J. J. A.
1980-01-01
Two computer programs are described for predicting the transient large deflection elastic viscoplastic responses of thin single layer, initially flat unstiffened or integrally stiffened, Kirchhoff-Lov ductile metal panels. The PLATE 1 program pertains to structural responses produced by prescribed externally applied transient loading or prescribed initial velocity distributions. The collision imparted velocity method PLATE 1 program concerns structural responses produced by impact of an idealized nondeformable fragment. Finite elements are used to represent the structure in both programs. Strain hardening and strain rate effects of initially isotropic material are considered.
Analysis of the thermal performance of heat pipe radiators
NASA Technical Reports Server (NTRS)
Boo, J. H.; Hartley, J. G.
1990-01-01
A comprehensive mathematical model and computational methodology are presented to obtain numerical solutions for the transient behavior of a heat pipe radiator in a space environment. The modeling is focused on a typical radiator panel having a long heat pipe at the center and two extended surfaces attached to opposing sides of the heat pipe shell in the condenser section. In the set of governing equations developed for the model, each region of the heat pipe - shell, liquid, and vapor - is thermally lumped to the extent possible, while the fin is lumped only in the direction normal to its surface. Convection is considered to be the only significant heat transfer mode in the vapor, and the evaporation and condensation velocity at the liquid-vapor interface is calculated from kinetic theory. A finite-difference numerical technique is used to predict the transient behavior of the entire radiator in response to changing loads.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Steiner, J.L.; Lime, J.F.; Elson, J.S.
One dimensional TRAC transient calculations of the process inherent ultimate safety (PIUS) advanced reactor design were performed for a pump-trip SCRAM. The TRAC calculations showed that the reactor power response and shutdown were in qualitative agreement with the one-dimensional analyses presented in the PIUS Preliminary Safety Information Document (PSID) submitted by Asea Brown Boveri (ABB) to the US Nuclear Regulatory Commission for preapplication safety review. The PSID analyses were performed with the ABB-developed RIGEL code. The TRAC-calculated phenomena and trends were also similar to those calculated with another one-dimensional PIUS model, the Brookhaven National Laboratory developed PIPA code. A TRACmore » pump-trip SCRAM transient has also been calculated with a TRAC model containing a multi-dimensional representation of the PIUS intemal flow structures and core region. The results obtained using the TRAC fully one-dimensional PIUS model are compared to the RIGEL, PIPA, and TRAC multi-dimensional results.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cina, Jeffrey A., E-mail: cina@uoregon.edu; Kovac, Philip A.; Jumper, Chanelle C.
We rebuild the theory of ultrafast transient-absorption/transmission spectroscopy starting from the optical response of an individual molecule to incident femtosecond pump and probe pulses. The resulting description makes use of pulse propagators and free molecular evolution operators to arrive at compact expressions for the several contributions to a transient-absorption signal. In this alternative description, which is physically equivalent to the conventional response-function formalism, these signal contributions are conveniently expressed as quantum mechanical overlaps between nuclear wave packets that have undergone different sequences of pulse-driven optical transitions and time-evolution on different electronic potential-energy surfaces. Using this setup in application to amore » simple, multimode model of the light-harvesting chromophores of PC577, we develop wave-packet pictures of certain generic features of ultrafast transient-absorption signals related to the probed-frequency dependence of vibrational quantum beats. These include a Stokes-shifting node at the time-evolving peak emission frequency, antiphasing between vibrational oscillations on opposite sides (i.e., to the red or blue) of this node, and spectral fingering due to vibrational overtones and combinations. Our calculations make a vibrationally abrupt approximation for the incident pump and probe pulses, but properly account for temporal pulse overlap and signal turn-on, rather than neglecting pulse overlap or assuming delta-function excitations, as are sometimes done.« less
Raphan, T
1998-05-01
This study evaluates the effects of muscle axis shifts on the performance of a vector velocity-position integrator in the CNS. Earlier models of the oculomotor plant assumed that the muscle axes remained fixed relative to the head as the eye rotated into secondary and tertiary eye positions. Under this assumption, the vector integrator model generates torsional transients as the eye moves from secondary to tertiary positions of fixation. The torsional transient represents an eye movement response to a spatial mismatch between the torque axes that remain fixed in the head and the displacement plane that changes by half the angle of the change in eye orientation. When muscle axis shifts were incorporated into the model, the torque axes were closer to the displacement plane at each eye orientation throughout the trajectory, and torsional transients were reduced dramatically. Their size and dynamics were close to reported data. It was also shown that when the muscle torque axes were rotated by 50% of the eye rotation, there was no torsional transient and Listing's law was perfectly obeyed. When muscle torque axes rotated >50%, torsional transients reversed direction compared with what occurred for muscle axis shifts of <50%. The model indicates that Listing's law is implemented by the oculomotor plant subject to a two-dimensional command signal that is confined to the pitch-yaw plane, having zero torsion. Saccades that bring the eye to orientations outside Listing's plane could easily be corrected by a roll pulse that resets the roll state of the velocity-position integrator to zero. This would be a simple implementation of the corrective controller suggested by Van Opstal and colleagues. The model further indicates that muscle axis shifts together with the torque orientation relationship for tissue surrounding the eye and Newton's laws of motion form a sufficient plant model to explain saccadic trajectories and periods of fixation when driven by a vector command confined to the pitch-yaw plane. This implies that the velocity-position integrator is probably realized as a subtractive feedback vector integrator and not as a quaternion-based integrator that implements kinematic transformations to orient the eye.
Hrabcová, Dana; Pásek, Michal; Šimurda, Jiří; Christé, Georges
2013-12-13
We have developed a computer model of human cardiac ventricular myocyte (CVM), including t-tubular and cleft spaces with the aim of evaluating the impact of accumulation-depletion of ions in restricted extracellular spaces on transmembrane ion transport and ionic homeostasis in human CVM. The model was based on available data from human CVMs. Under steady state, the effect of ion concentration changes in extracellular spaces on [Ca2+]i-transient was explored as a function of critical fractions of ion transporters in t-tubular membrane (not documented for human CVM). Depletion of Ca2+ and accumulation of K+ occurring in extracellular spaces slightly affected the transmembrane Ca2+ flux, but not the action potential duration (APD90). The [Ca2+]i-transient was reduced (by 2%-9%), depending on the stimulation frequency, the rate of ion exchange between t-tubules and clefts and fractions of ion-transfer proteins in the t-tubular membrane. Under non-steady state, the responses of the model to changes of stimulation frequency were analyzed. A sudden increase of frequency (1-2.5 Hz) caused a temporal decrease of [Ca2+] in both extracellular spaces, a reduction of [Ca2+]i-transient (by 15%) and APD90 (by 13 ms). The results reveal different effects of activity-related ion concentration changes in human cardiac t-tubules (steady-state effects) and intercellular clefts (transient effects) in the modulation of membrane ion transport and Ca2+ turnover.
Oyler-Yaniv, Jennifer; Oyler-Yaniv, Alon; Shakiba, Mojdeh; Min, Nina K; Chen, Ying-Han; Cheng, Sheue-Yann; Krichevsky, Oleg; Altan-Bonnet, Nihal; Altan-Bonnet, Grégoire
2017-06-01
Immune cells constantly survey the host for pathogens or tumors and secrete cytokines to alert surrounding cells of these threats. In vivo, activated immune cells secrete cytokines for several hours, yet an acute immune reaction occurs over days. Given these divergent timescales, we addressed how cytokine-responsive cells translate brief cytokine exposure into phenotypic changes that persist over long timescales. We studied melanoma cell responses to transient exposure to the cytokine interferon γ (IFNγ) by combining a systems-scale analysis of gene expression dynamics with computational modeling and experiments. We discovered that IFNγ is captured by phosphatidylserine (PS) on the surface of viable cells both in vitro and in vivo then slowly released to drive long-term transcription of cytokine-response genes. This mechanism introduces an additional function for PS in dynamically regulating inflammation across diverse cancer and primary cell types and has potential to usher in new immunotherapies targeting PS and inflammatory pathways. Published by Elsevier Inc.
NASA Astrophysics Data System (ADS)
Hu, Yanpu; Egbert, Gary; Ji, Yanju; Fang, Guangyou
2017-01-01
In this study, we apply fictitious wave domain (FWD) methods, based on the correspondence principle for the wave and diffusion fields, to finite difference (FD) modeling of transient electromagnetic (TEM) diffusion problems for geophysical applications. A novel complex frequency shifted perfectly matched layer (PML) boundary condition is adapted to the FWD to truncate the computational domain, with the maximum electromagnetic wave propagation velocity in the FWD used to set the absorbing parameters for the boundary layers. Using domains of varying spatial extent we demonstrate that these boundary conditions offer significant improvements over simpler PML approaches, which can result in spurious reflections and large errors in the FWD solutions, especially for low frequencies and late times. In our development, resistive air layers are directly included in the FWD, allowing simulation of TEM responses in the presence of topography, as is commonly encountered in geophysical applications. We compare responses obtained by our new FD-FWD approach and with the spectral Lanczos decomposition method on 3-D resistivity models of varying complexity. The comparisons demonstrate that our absorbing boundary condition in FWD for the TEM diffusion problems works well even in complex high-contrast conductivity models.
Thirumala, Parthasarathy; Zhou, James; Krishnan, Rohan; Manem, Nihita; Umredkar, Shreya; Hamilton, D K; Balzer, Jeffrey R; Oudega, Martin
2016-03-01
Iatrogenic spinal cord injury (SCI) is a cause of potentially debilitating post-operative neurologic complications. Currently, intra-operative neurophysiological monitoring (IONM) via somatosensory evoked potentials and motor-evoked potentials is used to detect and prevent impending SCI. However, no empirically validated interventions exist to halt the progression of iatrogenic SCI once it is detected. This is in part due to the lack of a suitable translational model that mimics the circumstances surrounding iatrogenic SCI detected via IONM. Here, we evaluate a model of simulated contusive iatrogenic SCI detected via IONM in adult female Sprague-Dawley rats. We show that transient losses of somatosensory evoked potentials responses are 88.24% sensitive (95% confidence interval [CI] 63.53-98.20) and 80% specific (95% CI 51.91-95.43) for significant functional impairment following simulated iatrogenic SCI. Similarly, we show that transient losses in motor-evoked potentials responses are 70.83% sensitive (95% CI 48.91-87.33) and 100% specific (95% CI 62.91-100.00) for significant functional impairment following simulated iatrogenic SCI. These results indicate that our model is a suitable replica of the circumstances surrounding clinical iatrogenic SCI. Copyright © 2015 Elsevier Ltd. All rights reserved.
Salciarini, D.; Godt, J.W.; Savage, W.Z.; Conversini, P.; Baum, R.L.; Michael, J.A.
2006-01-01
We model the rainfall-induced initiation of shallow landslides over a broad region using a deterministic approach, the Transient Rainfall Infiltration and Grid-based Slope-stability (TRIGRS) model that couples an infinite-slope stability analysis with a one-dimensional analytical solution for transient pore pressure response to rainfall infiltration. This model permits the evaluation of regional shallow landslide susceptibility in a Geographic Information System framework, and we use it to analyze susceptibility to shallow landslides in an area in the eastern Umbria Region of central Italy. As shown on a landslide inventory map produced by the Italian National Research Council, the area has been affected in the past by shallow landslides, many of which have transformed into debris flows. Input data for the TRIGRS model include time-varying rainfall, topographic slope, colluvial thickness, initial water table depth, and material strength and hydraulic properties. Because of a paucity of input data, we focus on parametric analyses to calibrate and test the model and show the effect of variation in material properties and initial water table conditions on the distribution of simulated instability in the study area in response to realistic rainfall. Comparing the results with the shallow landslide inventory map, we find more than 80% agreement between predicted shallow landslide susceptibility and the inventory, despite the paucity of input data.
Cascade flutter analysis with transient response aerodynamics
NASA Technical Reports Server (NTRS)
Bakhle, Milind A.; Mahajan, Aparajit J.; Keith, Theo G., Jr.; Stefko, George L.
1991-01-01
Two methods for calculating linear frequency domain aerodynamic coefficients from a time marching Full Potential cascade solver are developed and verified. In the first method, the Influence Coefficient, solutions to elemental problems are superposed to obtain the solutions for a cascade in which all blades are vibrating with a constant interblade phase angle. The elemental problem consists of a single blade in the cascade oscillating while the other blades remain stationary. In the second method, the Pulse Response, the response to the transient motion of a blade is used to calculate influence coefficients. This is done by calculating the Fourier Transforms of the blade motion and the response. Both methods are validated by comparison with the Harmonic Oscillation method and give accurate results. The aerodynamic coefficients obtained from these methods are used for frequency domain flutter calculations involving a typical section blade structural model. An eigenvalue problem is solved for each interblade phase angle mode and the eigenvalues are used to determine aeroelastic stability. Flutter calculations are performed for two examples over a range of subsonic Mach numbers.
PSH Transient Simulation Modeling
DOE Office of Scientific and Technical Information (OSTI.GOV)
Muljadi, Eduard
PSH Transient Simulation Modeling presentation from the WPTO FY14 - FY16 Peer Review. Transient effects are an important consideration when designing a PSH system, yet numerical techniques for hydraulic transient analysis still need improvements for adjustable-speed (AS) reversible pump-turbine applications.
Hasegawa, Kunihiro; Takahashi, Shin'ya
2013-01-01
Cognitive control in response compatibility tasks is modulated by the task context. Two types of contextual modulations have been demonstrated; sustained (block-wise) and transient (trial-by-trial). Recent research suggests that these modulations have different underlying mechanisms. This study presents new evidence supporting this claim by comparing false alarm (FA) responses on no-go trials of the Simon task between the sustained and transient contexts. In Experiment 1, the sustained context was manipulated so that a block included a larger number of incongruent trials. Results showed that participants made more FA responses by the hand opposite to the stimulus location. This suggests a generation of response bias in which the task-irrelevant location information is utilized in a reversed manner (i.e., to respond with the right hand to a stimulus presented on the left side and vice versa). Next, Experiment 2 examined the effect of the transient context and found that overall FA rate was lower when a no-go trial was preceded by an incongruent trial than by a congruent trial, whereas such response bias as that shown in Experiment 1 was not demonstrated. This suggests that the transient conflict context enhances inhibition of the task-irrelevant process but does not make the task-irrelevant information actively usable. Based on these results, we propound two types of cognitive control modulations as adaptive behaviors: response biasing based on utilization of the task-irrelevant information under the sustained conflict context and transient enhancement of inhibition of the task-irrelevant process based on the online conflict monitoring.
Feedback control of acoustic disturbance transient growth in triggering thermoacoustic instability
NASA Astrophysics Data System (ADS)
Zhao, Dan; Reyhanoglu, Mahmut
2014-08-01
Transient growth of acoustic disturbances could trigger thermoacoustic instability in a combustion system with non-orthogonal eigenmodes, even with stable eigenvalues. In this work, feedback control of transient growth of flow perturbations in a Rijke-type combustion system is considered. For this, a generalized thermoacoustic model with distributed monopole-like actuators is developed. The model is formulated in state-space to gain insights on the interaction between various eigenmodes and the dynamic response of the system to the actuators. Three critical parameters are identified: (1) the mode number, (2) the number of actuators, and (3) the locations of the actuators. It is shown that in general the number of the actuators K is related to the mode number N as K=N2. For simplicity in illustrating the main results of the paper, two different thermoacoustic systems are considered: system (a) with one mode and system (b) that involves two modes. The actuator location effect is studied in system (a) and it is found that the actuator location plays an important role in determining the control effort. In addition, sensitivity analysis of pressure- and velocity-related control parameters is conducted. In system (b), when the actuators are turned off (i.e., open-loop configuration), it is observed that acoustic energy transfers from the high frequency mode to the lower frequency mode. After some time, the energy is transferred back. Moreover, the high frequency oscillation grows into nonlinear limit cycle with the low frequency oscillation amplified. As a linear-quadratic regulator (LQR) is implemented to tune the actuators, both systems become asymptotically stable. However, the LQR controller fails in eliminating the transient growth, which may potentially trigger thermoacoustic instability. In order to achieve strict dissipativity (i.e., unity maximum transient growth), a transient growth controller is systematically designed and tested in both systems. Comparison is then made between the performance of the LQR controller and that of the transient growth controller. It is found in both systems that the transient growth controller achieves both exponential decay of the flow disturbance energy and unity maximum transient growth.
Transient triggering of near and distant earthquakes
Gomberg, J.; Blanpied, M.L.; Beeler, N.M.
1997-01-01
We demonstrate qualitatively that frictional instability theory provides a context for understanding how earthquakes may be triggered by transient loads associated with seismic waves from near and distance earthquakes. We assume that earthquake triggering is a stick-slip process and test two hypotheses about the effect of transients on the timing of instabilities using a simple spring-slider model and a rate- and state-dependent friction constitutive law. A critical triggering threshold is implicit in such a model formulation. Our first hypothesis is that transient loads lead to clock advances; i.e., transients hasten the time of earthquakes that would have happened eventually due to constant background loading alone. Modeling results demonstrate that transient loads do lead to clock advances and that the triggered instabilities may occur after the transient has ceased (i.e., triggering may be delayed). These simple "clock-advance" models predict complex relationships between the triggering delay, the clock advance, and the transient characteristics. The triggering delay and the degree of clock advance both depend nonlinearly on when in the earthquake cycle the transient load is applied. This implies that the stress required to bring about failure does not depend linearly on loading time, even when the fault is loaded at a constant rate. The timing of instability also depends nonlinearly on the transient loading rate, faster rates more rapidly hastening instability. This implies that higher-frequency and/or longer-duration seismic waves should increase the amount of clock advance. These modeling results and simple calculations suggest that near (tens of kilometers) small/moderate earthquakes and remote (thousands of kilometers) earthquakes with magnitudes 2 to 3 units larger may be equally effective at triggering seismicity. Our second hypothesis is that some triggered seismicity represents earthquakes that would not have happened without the transient load (i.e., accumulated strain energy would have been relieved via other mechanisms). We test this using two "new-seismicity" models that (1) are inherently unstable but slide at steady-state conditions under the background load and (2) are conditionally stable such that instability occurs only for sufficiently large perturbations. For the new-seismicity models, very small-amplitude transients trigger instability relative to the clock-advance models. The unstable steady-state models predict that the triggering delay depends inversely and nonlinearly on the transient amplitude (as in the clock-advance models). We were unable to generate delayed triggering with conditionally stable models. For both new-seismicity models, the potential for triggering is independent of when the transient load is applied or, equivalently, of the prestress (unlike in the clock-advance models). In these models, a critical triggering threshold appears to be inversely proportional to frequency. Further advancement of our understanding will require more sophisticated, quantitative models and observations that distinguish between our qualitative, yet distinctly different, model predictions.
The modelling of an SF6 arc in a supersonic nozzle: II. Current zero behaviour of the nozzle arc
NASA Astrophysics Data System (ADS)
Zhang, Q.; Liu, J.; Yan, J. D.; Fang, M. T. C.
2016-08-01
The present work (part II) forms the second part of an investigation into the behaviour of SF6 nozzle arc. It is concerned with the aerodynamic and electrical behaviour of a transient nozzle arc under a current ramp specified by a rate of current decay (di/dt) before current zero and a voltage ramp (dV/dt) after current zero. The five flow models used in part I [1] for cold gas flow and DC nozzle arcs have been applied to study the transient arc at three stagnation pressures (P 0) and two values of di/dt for the current ramp, representing a wide range of arcing conditions. An analysis of the physical mechanisms encompassed in each flow model is given with an emphasis on the adequacy of a particular model in describing the rapidly varying arc around current zero. The critical rate of rise of recovery voltage (RRRV) is found computationally and compared with test results of Benenson et al [2]. For transient nozzle arcs, the RRRV is proportional to the square of P 0, rather than to the square root of P 0 for DC nozzle arcs. The physical mechanisms responsible for the strong dependence of RRRV on P 0 have been investigated. The relative merits of the flow models employed are discussed.
Kleynhans, E; Clusella-Trullas, S; Terblanche, J S
2014-02-01
Physiological responses to transient conditions may result in costly responses with little fitness benefits, and therefore, a trade-off must exist between the speed of response and the duration of exposure to new conditions. Here, using the puparia of an important insect disease vector, Glossina pallidipes, we examine this potential trade-off using a novel combination of an experimental approach and a population dynamics model. Specifically, we explore and dissect the interactions between plastic physiological responses, treatment-duration and -intensity using an experimental approach. We then integrate these experimental results from organismal water-balance data and their plastic responses into a population dynamics model to examine the potential relative fitness effects of simulated transient weather conditions on population growth rates. The results show evidence for the predicted trade-off for plasticity of water loss rate (WLR) and the duration of new environmental conditions. When altered environmental conditions lasted for longer durations, physiological responses could match the new environmental conditions, and this resulted in a lower WLR and lower rates of population decline. At shorter time-scales however, a mismatch between acclimation duration and physiological responses was reflected by reduced overall population growth rates. This may indicate a potential fitness cost due to insufficient time for physiological adjustments to take place. The outcomes of this work therefore suggest plastic water balance responses have both costs and benefits, and these depend on the time-scale and magnitude of variation in environmental conditions. These results are significant for understanding the evolution of plastic physiological responses and changes in population abundance in the context of environmental variability. © 2014 The Authors. Journal of Evolutionary Biology © 2014 European Society For Evolutionary Biology.
Dynamics of mechanical feedback-type hydraulic servomotors under inertia loads
NASA Technical Reports Server (NTRS)
Gold, Harold; Otto, Edward W; Ransom, Victor L
1953-01-01
An analysis of the dynamics of mechanical feedback-type hydraulic servomotors under inertia loads is developed and experimental verification is presented. The analysis, which is developed in terms of two physical parameters, yields direct expressions for the following dynamic responses: (1) the transient response to a step input and the maximum cylinder pressure during the transient and (2) the variation of amplitude attenuation and phase shift with the frequency of a sinusoidally varying input. The validity of the analysis is demonstrated by means of recorded transient and frequency responses obtained on two servomotors. The calculated responses are in close agreement with the measured responses. The relations presented are readily applicable to the design as well as to the analysis of hydraulic servomotors.
Estimating the impact of oyster restoration scenarios on transient fish production
McCoy, Elizabeth; Borrett, Stuart R.; LaPeyre, Megan K.; Peterson, Bradley J.
2017-01-01
Oyster reef restoration projects are increasing in number both to enhance oyster density and to retain valuable ecosystem services provided by oyster reefs. Although some oyster restoration projects have demonstrated success by increasing density and biomass of transient fish, it still remains a challenge to quantify the effects of oyster restoration on transient fish communities. We developed a bioenergetics model to assess the impact of selected oyster reef restoration scenarios on associated transient fish species. We used the model to analyze the impact of changes in (1) oyster population carrying capacity; (2) oyster population growth rate; and (3) diet preference of transient fish on oyster reef development and associated transient fish species. Our model results indicate that resident fish biomass is directly affected by oyster restoration and oyster biomass, and oyster restoration can have cascading impacts on transient fish biomass. Furthermore, the results highlight the importance of a favorable oyster population growth rate during early restoration years, as it can lead to rapid increases in mean oyster biomass and biomass of transient fish species. The model also revealed that a transient fish's diet solely dependent on oyster reef-derived prey could limit the biomass of transient fish species, emphasizing the importance of habitat connectivity in estuarine areas to enhance transient fish species biomass. Simple bioenergetics models can be developed to understand the dynamics of a system and make qualitative predictions of management and restoration scenarios.
Transient lower esophageal sphincter relaxation and esophageal motor response.
Schneider, Joachim H; Küper, Markus A; Königsrainer, Alfred; Brücher, Björn L D M
2010-04-01
Gastroesophageal reflux is caused by transient lower esophageal sphincter relaxations (TLESRs) in healthy individuals and in most patients with gastroesophageal reflux disease (GERD). Refluxate is normally propelled by pharyngeally induced swallowing events, but TLESRs may also be accompanied by retrograde esophageal motor responses (EMRs). These contractions have not previously been investigated and their effect on esophageal clearance is not known. The aim of this study was to assess the frequency of EMRs after TLESR in healthy individuals and GERD patients and to develop an animal model for further investigation of EMRs. The frequency of TLESRs and esophageal body contractions after TLESRs was assessed using ambulatory manometry in five healthy individuals and five GERD patients. An animal model was developed for reproducible provocation of TLESRs and subsequent EMRs. Patients with GERD have significantly more TLESRs than healthy individuals. However, post-TLESR EMRs were not more frequent in the GERD group. All post-TLESR EMRs presented as simultaneous contractions of the esophagus. The feline model allowed reproducible initiation of the esophageal motor response after TLESR, showing that EMRs can be induced by external mechanoreceptor stimulation simultaneously with LES relaxation. This experimental design imitates the conditions after fundoplication in humans. The study demonstrated that GERD patients have significantly more TLESRs in comparison with healthy individuals, but these were only incidental to EMRs. Further research is needed to improve our understanding of esophageal motility disorders. The animal model presented offers a feasible tool for investigating TLESR-induced esophageal motility.
Transient response in granular quasi-two-dimensional bounded heap flow.
Xiao, Hongyi; Ottino, Julio M; Lueptow, Richard M; Umbanhowar, Paul B
2017-10-01
We study the transition between steady flows of noncohesive granular materials in quasi-two-dimensional bounded heaps by suddenly changing the feed rate. In both experiments and simulations, the primary feature of the transition is a wedge of flowing particles that propagates downstream over the rising free surface with a wedge front velocity inversely proportional to the square root of time. An additional longer duration transient process continues after the wedge front reaches the downstream wall. The entire transition is well modeled as a moving boundary problem with a diffusionlike equation derived from local mass balance and a local relation between the flux and the surface slope.
NASA Astrophysics Data System (ADS)
Johnson, B.; Zhurina, E. N.
2001-12-01
We are developing and assessing field testing and analysis methodologies for quantitative characterization of aquifer heterogenities using data measured in an array of multilevel monitoring wells (MLW) during pumping and recovery well tests. We have developed a unique field laboratory to determine the permeability field in a 20m by 40m by 70m volume in the fault partitioned, siliciclastic Hickory aquifer system in central Texas. The site incorporates both stratigraphic variations and a normal fault system that partially offsets the aquifer and impedes cross-fault flow. We constructed a high-resolution geologic model of the site based upon 1050 m of core and a suite of geophysical logs from eleven, closely spaced (3-10m), continuously cored boreholes to depths of 125 m. Westbay multilevel monitoring systems installed in eight holes provide 94 hydraulically isolated measurement zones and 25 injection zones. A good geologic model is critical to proper installation of the MLW. Packers are positioned at all significant fault piercements and selected, laterally extensive, clay-rich strata. Packers in adjacent MLW bracket selected hydrostratigraphic intervals. Pump tests utilized two, uncased, fully penetrating irrigation wells that straddle the fault system and are in close proximity (7 to 65 m) to the MLW. Pumping and recovery transient pressure histories were measured in 85 zones using pressure transducers with a resolution of 55 Pa (0.008 psi). The hydraulic response is that of an anisotropic, unconfined aquifer. The transient pressure histories vary significantly from zone to zone in a single MLW as well as between adjacent MLW. Derivative plots are especially useful for differentiating details of pressure histories. Based on the geologic model, the derivative curve of a zone reflects its absolute vertical position, vertical stratigraphic position, and proximity to either a fault or significant stratigraphic heterogeneity. Additional forward modeling is needed to assist qualitative interpretation of response curves. Prior geologic knowledge appears critical. Quantitative interpretation of the transient pressure histories requires utilizing a numerical aquifer response model coupled with a geophysical inversion algorithm.
So, Rosa Q; McConnell, George C; Grill, Warren M
2017-03-01
Methamphetamine-induced circling is used to quantify the behavioral effects of subthalamic nucleus (STN) deep brain stimulation (DBS) in hemiparkinsonian rats. We observed a frequency-dependent transient effect of DBS on circling, and quantified this effect to determine its neuronal basis. High frequency STN DBS (75-260Hz) resulted in transient circling contralateral to the lesion at the onset of stimulation, which was not sustained after the first several seconds of stimulation. Following the transient behavioral change, DBS resulted in a frequency-dependent steady-state reduction in pathological ipsilateral circling, but no change in overall movement. Recordings from single neurons in globus pallidus externa (GPe) and substantia nigra pars reticulata (SNr) revealed that high frequency, but not low frequency, STN DBS elicited transient changes in both firing rate and neuronal oscillatory power at the stimulation frequency in a subpopulation of GPe and SNr neurons. These transient changes were not sustained, and most neurons exhibited a different response during the steady-state phase of DBS. During the steady-state, DBS produced elevated neuronal oscillatory power at the stimulus frequency in a majority of GPe and SNr neurons, and the increase was more pronounced during high frequency DBS than during low frequency DBS. Changes in oscillatory power during both transient and steady-state DBS were highly correlated with changes in firing rates. These results suggest that distinct neural mechanisms were responsible for transient and sustained behavioral responses to STN DBS. The transient contralateral turning behavior following the onset of high frequency DBS was paralleled by transient changes in firing rate and oscillatory power in the GPe and SNr, while steady-state suppression of ipsilateral turning was paralleled by sustained increased synchronization of basal ganglia neurons to the stimulus pulses. Our analysis of distinct frequency-dependent transient and steady-state responses to DBS lays the foundation for future mechanistic studies of the immediate and persistent effects of DBS. Copyright © 2016 Elsevier B.V. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wheatley, P.D.; Wagner, K.C.
The FIST power transient test 6PMC2 was analyzed to further the understanding of the FIST facility and provide an assessment of TRAC-BD1/MOD1. FIST power transient 6PMC2 investigated the thermal-hydraulic response following inadvertent closure of the main steam isolation valve and the subsequent failure of the reactor to scram. Failure of the high pressure core spray system was also assumed, resulting on only the reactor core isolation cooling flow for inventory makeup during the transient. The experiment was a sensitivity study with relatively high core power and low makeup rates. This study provides one of the first opportunities to assess TRAC-BD1/MOD1more » under power transient and natural circulation conditions with data from a facility with prototypical BWR geometry. The power transient test was analyzed with emphasis on the following phenomena; (a) the system pressure response, (b) the natural circulation flows and rates, and (c) the heater rod cladding temperature response. Based on the results of this study, TRAC-BD1/MOD1 can be expected to calculate the thermal-hydraulic behavior of a BWR during a power transient.« less
NASA Astrophysics Data System (ADS)
Amaral, P.; Marques, R.; Zêzere, J. L.; Marques, F.; Queiroz, G.
2009-04-01
In the last 15 years, several heavy rainstorms have occurred in Povoação County (S. Miguel Island, Azores), namely in the Ribeira Quente Valley. These rainfall events have triggered hundreds of shallow landslides that killed tens of people and have been responsible for direct and indirect damages amounting to tens of millions of Euros. On the 6th March 2005 an intense rainfall episode, up to 160 mm of rain in less than 24 h, triggered several shallow landslides that caused 3 victims and damaged/blocked roads. The Ribeira Quente Valley has an area of about 9.5 km2 and is mainly constituted by pyroclastic materials (pumice ash and lapilli), that were produced by the Furnas Volcano explosive eruptions. To provide an assessment of slope-failure conditions for the 6th March 2005 rainfall event, it was applied a distributed transient response model for slope stability analysis. The adopted methodology is a modified version of Iversońs (2000) transient response model, which couple an infinite slope stability analysis with an analytic solution of the Richard's equation for vertical water infiltration in quasi-saturated soil. The validation was made on two different scales: (1) at a slope scale, using two distinct test sites where landslides were triggered; and (2) at the basin scale, using the entire landslide database and generalizing the modeling input parameters for the regional spatialization of results. At the slope scale, the obtained results were very accurate, and it was possible to predict the precise time of the slope failures. At the basin scale, the obtained results were very conservative, even though the model predicted all the observed landslide locations, in the 23.7% of the area classified as untable at the time of the slope failures. This methodology revealed to be a reasonable tool for landslide forecast for both temporal and spatial distributions, on both slope and regional scales. In the future, the model components will be integrated into a GIS based system that will publish the FS values to a WebGIS platform, based on near real time ground-based rainfall monitoring. This application will allow the evaluation of scenarios considering the variation of the pressure head response, related to transient rainfall regime. The resultant computational platform combined with regional empirical rainfall triggered landslides threshold (Marques et al. 2008) can be incorporated in a common server with the Regional Civil Protection for emergency planning purposes. This work is part of the project VOLCSOILRISK (Volcanic Soils Geotechnical Characterization for Landslide Risk Mitigation), supported by Direcção Regional da Ciência e Tecnologia do Governo Regional dos Açores. References: IVERSON, R.M. (2000) - Landslide triggering by rain infiltration. Water Resources Research 36, 1897-1910. MARQUES, R., ZÊZERE, J.L., TRIGO, R., GASPAR, J.L., TRIGO, I. (2008) - Rainfall patterns and critical values associated with landslides in Povoação County (São Miguel Island, Azores): relationships with the North Atlantic Oscillation. Hydrol. Process. 22, 478-494. DOI: 10.1002/hyp.6879.
Force transients and minimum cross-bridge models in muscular contraction
Halvorson, Herbert R.
2010-01-01
Two- and three-state cross-bridge models are considered and examined with respect to their ability to predict three distinct phases of the force transients that occur in response to step change in muscle fiber length. Particular attention is paid to satisfying the Le Châtelier–Brown Principle. This analysis shows that the two-state model can account for phases 1 and 2 of a force transient, but is barely adequate to account for phase 3 (delayed force) unless a stretch results in a sudden increase in the number of cross-bridges in the detached state. The three-state model (A → B → C → A) makes it possible to account for all three phases if we assume that the A → B transition is fast (corresponding to phase 2), the B → C transition is of intermediate speed (corresponding to phase 3), and the C → A transition is slow; in such a scenario, states A and C can support or generate force (high force states) but state B cannot (detached, or low-force state). This model involves at least one ratchet mechanism. In this model, force can be generated by either of two transitions: B → A or B → C. To determine which of these is the major force-generating step that consumes ATP and transduces energy, we examine the effects of ATP, ADP, and phosphate (Pi) on force transients. In doing so, we demonstrate that the fast transition (phase 2) is associated with the nucleotide-binding step, and that the intermediate-speed transition (phase 3) is associated with the Pi-release step. To account for all the effects of ligands, it is necessary to expand the three-state model into a six-state model that includes three ligand-bound states. The slowest phase of a force transient (phase 4) cannot be explained by any of the models described unless an additional mechanism is introduced. Here we suggest a role of series compliance to account for this phase, and propose a model that correlates the slowest step of the cross-bridge cycle (transition C → A) to: phase 4 of step analysis, the rate constant ktr of the quick-release and restretch experiment, and the rate constant kact for force development time course following Ca2+ activation. PMID:18425593
Force transients and minimum cross-bridge models in muscular contraction.
Kawai, Masataka; Halvorson, Herbert R
2007-01-01
Two- and three-state cross-bridge models are considered and examined with respect to their ability to predict three distinct phases of the force transients that occur in response to step change in muscle fiber length. Particular attention is paid to satisfying the Le Châtelier-Brown Principle. This analysis shows that the two-state model can account for phases 1 and 2 of a force transient, but is barely adequate to account for phase 3 (delayed force) unless a stretch results in a sudden increase in the number of cross-bridges in the detached state. The three-state model (A-->B-->C-->A) makes it possible to account for all three phases if we assume that the A-->B transition is fast (corresponding to phase 2), the B-->A transition is of intermediate speed (corresponding to phase 3), and the C-->A transition is slow; in such a scenario, states A and C can support or generate force (high force states) but state B cannot (detached, or low-force state). This model involves at least one ratchet mechanism. In this model, force can be generated by either of two transitions: B-->A or B-->C. To determine which of these is the major force-generating step that consumes ATP and transduces energy, we examine the effects of ATP, ADP, and phosphate (Pi) on force transients. In doing so, we demonstrate that the fast transition (phase 2) is associated with the nucleotide-binding step, and that the intermediate-speed transition (phase 3) is associated with the Pi-release step. To account for all the effects of ligands, it is necessary to expand the three-state model into a six-state model that includes three ligand-bound states. The slowest phase of a force transient (phase 4) cannot be explained by any of the models described unless an additional mechanism is introduced. Here we suggest a role of series compliance to account for this phase, and propose a model that correlates the slowest step of the cross-bridge cycle (transition C-->A) to: phase 4 of step analysis, the rate constant k(tr) of the quick-release and restretch experiment, and the rate constant k(act) for force development time course following Ca(2+) activation.
Tropic responses of Phycomyces sporangiophores to gravitational and centrifugal stimuli.
DENNISON, D S
1961-09-01
A low-speed centrifuge was used to study the tropic responses of Phycomyces sporangiophores in darkness to the stimulus of combined gravitational and centrifugal forces. If this stimulus is constant the response is a relatively slow tropic reaction, which persists for up to 12 hours. The response is accelerated by increasing the magnitude of the gravitational-centrifugal force. A wholly different tropic response, the transient response, is elicited by an abrupt change in the gravitational-centrifugal stimulus. The transient response has a duration of only about 6 min. but is characterized by a high bending speed (about 5 degrees /min.). An analysis of the distribution of the transient response along the growing zone shows that the active phase of the response has a distribution similar to that of the light sensitivity for the light-growth and phototropic responses. Experiments in which sporangiophores are centrifuged in an inert dense fluid indicate that the sensory mechanism of the transient response is closely related to the physical deformation of the growing zone caused by the action of the gravitational-centrifugal force on the sporangiophore as a whole. However, the response to a steady gravitational-centrifugal force is most likely not connected with this deformation, but is probably triggered by the shifting of regions or particles of differing density relative to one another inside the cell.
Bayguinov, Orline; Hagen, Brian; Sanders, Kenton M
2003-01-01
Neurokinins contribute to the neural regulation of gastrointestinal (GI) smooth muscles. We studied responses of murine colonic smooth muscle cells to substance P (SP) and NK1 and NK2 agonists using confocal microscopy and the patch clamp technique. Colonic myocytes generated localized Ca2+ transients that were coupled to spontaneous transient outward currents (STOCs). SP (10−10 M) increased Ca2+ transients and STOCs. Higher concentrations of SP (10−6 M) increased basal Ca2+ and inhibited Ca2+ transients and STOCs. Effects of SP were due to increased Ca2+ entry via L-type Ca2+ channels, and were mediated by protein kinase C (PKC). Nifedipine (10−6 M) and the PKC inhibitor, GF 109203X (10−6 M) reduced L-type Ca2+ current and blocked the effects of SP. SP responses depended upon parallel stimulation of NK1 and NK2 receptors. NK1 agonist ([Sar9,Met(O2)11]-substance P; SSP) and NK2 agonists (neurokinin A (NKA) or GR-64349) did not mimic the effects of SP alone, but NK1 and NK2 agonists were effective when added in combination (10−10–10−6 M). Consistent with this, either an NK1-specific antagonist (GR-82334; 10−7 M) or an NK2-specific antagonist (MEN 10,627; 10−7 M) blocked responses to SP (10−6 M). Ryanodine (10−5 M) blocked the increase in Ca2+ transients and STOCs in response to SP (10−10 M). Our findings show that low concentrations of SP, via PKC-dependent enhancement of L-type Ca2+ current and recruitment of ryanodine receptors, stimulate Ca2+ transients. At higher concentrations of SP (10−6 M), basal Ca2+ increases and spontaneous Ca2+ transients and STOCs are inhibited. PMID:12711623
Cárdenas, Luis; Martínez, Adán; Sánchez, Federico; Quinto, Carmen
2008-12-01
The role of reactive oxygen species (ROS) in root-nodule development and metabolism has been extensively studied. However, there is limited evidence showing ROS changes during the earliest stages of the interaction between legumes and rhizobia. Herein, using ratio-imaging analysis, increasing and transient ROS levels were detected at the tips of actively growing root hair cells within seconds after addition of Nod factors (NFs). This transient response (which lasted up to 3 min) was Nod-factor-specific, as chitin oligomers (pentamers) failed to induce a similar response. When chitosan, a fungal elicitor, or ATP was used instead, a sustained increasing signal was observed. As ROS levels are transiently elevated after the perception of NFs, we propose that this ROS response is characteristic of the symbiotic interaction. Furthermore, we discuss the remarkable spatial and temporal coincidences between ROS and transiently increased calcium levels observed in root hair cells immediately after the detection of NFs.
Transient photoresponse in amorphous In-Ga-Zn-O thin films under stretched exponential analysis
NASA Astrophysics Data System (ADS)
Luo, Jiajun; Adler, Alexander U.; Mason, Thomas O.; Bruce Buchholz, D.; Chang, R. P. H.; Grayson, M.
2013-04-01
We investigated transient photoresponse and Hall effect in amorphous In-Ga-Zn-O thin films and observed a stretched exponential response which allows characterization of the activation energy spectrum with only three fit parameters. Measurements of as-grown films and 350 K annealed films were conducted at room temperature by recording conductivity, carrier density, and mobility over day-long time scales, both under illumination and in the dark. Hall measurements verify approximately constant mobility, even as the photoinduced carrier density changes by orders of magnitude. The transient photoconductivity data fit well to a stretched exponential during both illumination and dark relaxation, but with slower response in the dark. The inverse Laplace transforms of these stretched exponentials yield the density of activation energies responsible for transient photoconductivity. An empirical equation is introduced, which determines the linewidth of the activation energy band from the stretched exponential parameter β. Dry annealing at 350 K is observed to slow the transient photoresponse.
Modeling rainfall conditions for shallow landsliding in Seattle, Washington
Godt, Jonathan W.; Schulz, William H.; Baum, Rex L.; Savage, William Z.
2008-01-01
We describe the results from an application of a distributed, transient infiltration–slope-stability model for an 18 km2 area of southwestern Seattle, Washington, USA. The model (TRIGRS) combines an infinite slope-stability calculation and an analytic, one-dimensional solution for pore-pressure diffusion in a soil layer of finite depth in response to time-varying rainfall. The transient solution for pore-pressure response can be superposed on any steady-state groundwater-flow field that is consistent with model assumptions. Applied over digital topography, the model computes a factor of safety for each grid cell at any time during a rainstorm. Input variables may vary from cell to cell, and the rainfall rate can vary in both space and time. For Seattle, topographic slope derived from an airborne laser swath mapping (ALSM)–based 3 m digital elevation model (DEM), maps of soil and water-table depths derived from geotechnical borings, and hourly rainfall intensities were used as model inputs. Material strength and hydraulic properties used in the model were determined from field and laboratory measurements, and a tension-saturated initial condition was assumed. Results are given in terms of a destabilizing intensity and duration of rainfall, and they were evaluated by comparing the locations of 212 historical landslides with the area mapped as potentially unstable. Because the equations of groundwater flow are explicitly solved with respect to time, the results from TRIGRS simulations can be portrayed quantitatively to assess the potential landslide hazard based on rainfall conditions.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Stroh, K.R.
1980-01-01
The Composite HTGR Analysis Program (CHAP) consists of a model-independent systems analysis mainframe named LASAN and model-dependent linked code modules, each representing a component, subsystem, or phenomenon of an HTGR plant. The Fort St. Vrain (FSV) version (CHAP-2) includes 21 coded modules that model the neutron kinetics and thermal response of the core; the thermal-hydraulics of the reactor primary coolant system, secondary steam supply system, and balance-of-plant; the actions of the control system and plant protection system; the response of the reactor building; and the relative hazard resulting from fuel particle failure. FSV steady-state and transient plant data are beingmore » used to partially verify the component modeling and dynamic smulation techniques used to predict plant response to postulated accident sequences.« less
NASA Technical Reports Server (NTRS)
Giltrud, M. E.; Lucas, D. S.
1979-01-01
The transient response of an elastic cylindrical shell immersed in an acoustic media that is engulfed by a plane wave is determined numerically. The method applies to the USA-STAGS code which utilizes the finite element method for the structural analysis and the doubly asymptotic approximation for the fluid-structure interaction. The calculations are compared to an exact analysis for two separate loading cases: a plane step wave and an exponentially decaying plane wave.
Transient analysis mode participation for modal survey target mode selection using MSC/NASTRAN DMAP
NASA Technical Reports Server (NTRS)
Barnett, Alan R.; Ibrahim, Omar M.; Sullivan, Timothy L.; Goodnight, Thomas W.
1994-01-01
Many methods have been developed to aid analysts in identifying component modes which contribute significantly to component responses. These modes, typically targeted for dynamic model correlation via a modal survey, are known as target modes. Most methods used to identify target modes are based on component global dynamic behavior. It is sometimes unclear if these methods identify all modes contributing to responses important to the analyst. These responses are usually those in areas of hardware design concerns. One method used to check the completeness of target mode sets and identify modes contributing significantly to important component responses is mode participation. With this method, the participation of component modes in dynamic responses is quantified. Those modes which have high participation are likely modal survey target modes. Mode participation is most beneficial when it is used with responses from analyses simulating actual flight events. For spacecraft, these responses are generated via a structural dynamic coupled loads analysis. Using MSC/NASTRAN DMAP, a method has been developed for calculating mode participation based on transient coupled loads analysis results. The algorithm has been implemented to be compatible with an existing coupled loads methodology and has been used successfully to develop a set of modal survey target modes.
Hight, Ariel E; Kalluri, Radha
2016-08-01
The vestibular nerve is characterized by two broad groups of neurons that differ in the timing of their interspike intervals; some fire at highly regular intervals, whereas others fire at highly irregular intervals. Heterogeneity in ion channel properties has been proposed as shaping these firing patterns (Highstein SM, Politoff AL. Brain Res 150: 182-187, 1978; Smith CE, Goldberg JM. Biol Cybern 54: 41-51, 1986). Kalluri et al. (J Neurophysiol 104: 2034-2051, 2010) proposed that regularity is controlled by the density of low-voltage-activated potassium currents (IKL). To examine the impact of IKL on spike timing regularity, we implemented a single-compartment model with three conductances known to be present in the vestibular ganglion: transient sodium (gNa), low-voltage-activated potassium (gKL), and high-voltage-activated potassium (gKH). Consistent with in vitro observations, removing gKL depolarized resting potential, increased input resistance and membrane time constant, and converted current step-evoked firing patterns from transient (1 spike at current onset) to sustained (many spikes). Modeled neurons were driven with a time-varying synaptic conductance that captured the random arrival times and amplitudes of glutamate-driven synaptic events. In the presence of gKL, spiking occurred only in response to large events with fast onsets. Models without gKL exhibited greater integration by responding to the superposition of rapidly arriving events. Three synaptic conductance were modeled, each with different kinetics to represent a variety of different synaptic processes. In response to all three types of synaptic conductance, models containing gKL produced spike trains with irregular interspike intervals. Only models lacking gKL when driven by rapidly arriving small excitatory postsynaptic currents were capable of generating regular spiking. Copyright © 2016 the American Physiological Society.
Thermal characterizations analysis of high-power ThinGaN cool-white light-emitting diodes
NASA Astrophysics Data System (ADS)
Raypah, Muna E.; Devarajan, Mutharasu; Ahmed, Anas A.; Sulaiman, Fauziah
2018-03-01
Analysis of thermal properties plays an important role in the thermal management of high-power (HP) lighting-emitting diodes (LEDs). Thermal resistance, thermal capacitance, and thermal time constant are essential parameters for the optimal design of the LED device and system, particularly for dynamic performance study. In this paper, thermal characterization and thermal time constant of ThinGaN HP LEDs are investigated. Three HP cool-white ThinGaN LEDs from different manufacturers are used in this study. A forward-voltage method using thermal transient tester (T3Ster) system is employed to determine the LEDs' thermal parameters at various operating conditions. The junction temperature transient response is described by a multi-exponential function model to extract thermal time constants. The transient response curve is divided into three layers and expressed by three exponential functions. Each layer is associated with a particular thermal time constant, thermal resistance, and thermal capacitance. It is found that the thermal time constant of LED package is on the order of 22 to 100 ms. Comparison between the experimental results is carried out to show the design effects on thermal performance of the LED package.
Systems analysis of the single photon response in invertebrate photoreceptors.
Pumir, Alain; Graves, Jennifer; Ranganathan, Rama; Shraiman, Boris I
2008-07-29
Photoreceptors of Drosophila compound eye employ a G protein-mediated signaling pathway that transduces single photons into transient electrical responses called "quantum bumps" (QB). Although most of the molecular components of this pathway are already known, the system-level understanding of the mechanism of QB generation has remained elusive. Here, we present a quantitative model explaining how QBs emerge from stochastic nonlinear dynamics of the signaling cascade. The model shows that the cascade acts as an "integrate and fire" device and explains how photoreceptors achieve reliable responses to light although keeping low background in the dark. The model predicts the nontrivial behavior of mutants that enhance or suppress signaling and explains the dependence on external calcium, which controls feedback regulation. The results provide insight into physiological questions such as single-photon response efficiency and the adaptation of response to high incident-light level. The system-level analysis enabled by modeling phototransduction provides a foundation for understanding G protein signaling pathways less amenable to quantitative approaches.
NASA Technical Reports Server (NTRS)
Ramaty, R.; Bussard, R. W.; Lingenfelter, R. E.
1981-01-01
Positron-electron pair radiation is examined as a mechanism that could be responsible for the impulsive phase emission of the 5 March, 1979 transient. Synchrotron cooling and subsequent annihilation of the pairs can account for the energy spectrum, the very high brightness, and the 0.4 MeV feature observed from this transient, whose source is likely to be a neutron star in the supernova remnant N49 in the Large Magellanic Cloud. In this model, the observed radiation is produced in the skin layer of a hot, radiation-dominated pair atmosphere, probably confined to the vicinity of the neutron star by a strong magnetic field. In this layer, about 10 to the 12th generations of pairs are formed (by photon-photon collisions), cooled and annihilated during the 0.15 s duration of the impulsive phase.
NASA Technical Reports Server (NTRS)
Brown, Andrew M.; Schmauch, Preston
2011-01-01
Turbine blades in rocket and jet engine turbomachinery experience enormous harmonic loading conditions. These loads result from the integer number of upstream and downstream stator vanes as well as the other turbine stages. Assessing the blade structural integrity is a complex task requiring an initial characterization of whether resonance is possible and then performing a forced response analysis if that condition is met. The standard technique for forced response analysis in rocket engines is to decompose a CFD-generated flow field into its harmonic components, and to then perform a frequency response analysis at the problematic natural frequencies. Recent CFD analysis and water-flow testing at NASA/MSFC, though, indicates that this technique may miss substantial harmonic and non-harmonic excitation sources that become present in complex flows. A substantial effort has been made to account for this denser spatial Fourier content in frequency response analysis (described in another paper by the author), but the question still remains whether the frequency response analysis itself is capable of capturing the excitation content sufficiently. Two studies comparing frequency response analysis with transient response analysis, therefore, of bladed-disks undergoing this complex flow environment have been performed. The first is of a bladed disk with each blade modeled by simple beam elements. Six loading cases were generated by varying a baseline harmonic excitation in different ways based upon cold-flow testing from Heritage Fuel Air Turbine Test. It was hypothesized that the randomness and other variation from the standard harmonic excitation would reduce the blade structural response, but the results showed little reduction. The second study was of a realistic model of a bladed-disk excited by the same CFD used in the J2X engine program. It was hypothesized that enforcing periodicity in the CFD (inherent in the frequency response technique) would overestimate the response. The results instead showed that the transient analysis results were up to 10% higher for "clean" nodal diameter excitations and six times larger for "messy" excitations, where substantial Fourier content around the main harmonic exists. Because the bulk of resonance problems are due to the "clean" excitations, a 10% underprediction is not necessarily a problem, especially since the average response in the transient is similar to the frequency response result, and so in a realistic finite life calculation, the life would be same. However, in the rare cases when the "messy" excitations harmonics are identified as the source of potential resonance concerns, this research does indicate that frequency response analysis is inadequate for accurate characterization of blade structural capability.
2012-01-01
Background Oestrogenic contaminants are widespread in the aquatic environment and have been shown to induce adverse effects in both wildlife (most notably in fish) and humans, raising international concern. Available detecting and testing systems are limited in their capacity to elucidate oestrogen signalling pathways and physiological impacts. Here we developed a transient expression assay to investigate the effects of oestrogenic chemicals in fish early life stages and to identify target organs for oestrogenic effects. To enhance the response sensitivity to oestrogen, we adopted the use of multiple tandem oestrogen responsive elements (EREc38) in a Tol2 transposon mediated Gal4ff-UAS system. The plasmid constructed (pTol2_ERE-TATA-Gal4ff), contains three copies of oestrogen response elements (3ERE) that on exposure to oestrogen induces expression of Gal4ff which this in turn binds Gal4-responsive Upstream Activated Sequence (UAS) elements, driving the expression of a second reporter gene, EGFP (Enhanced Green Fluorescent Protein). Results The response of our construct to oestrogen exposure in zebrafish embryos was examined using a transient expression assay. The two plasmids were injected into 1–2 cell staged zebrafish embryos, and the embryos were exposed to various oestrogens including the natural steroid oestrogen 17ß-oestradiol (E2), the synthetic oestrogen 17α- ethinyloestradiol (EE2), and the relatively weak environmental oestrogen nonylphenol (NP), and GFP expression was examined in the subsequent embryos using fluorescent microscopy. There was no GFP expression detected in unexposed embryos, but specific and mosaic expression of GFP was detected in the liver, heart, somite muscle and some other tissue cells for exposures to steroid oestrogen treatments (EE2; 10 ng/L, E2; 100 ng/L, after 72 h exposures). For the NP exposures, GFP expression was observed at 10 μg NP/L after 72 h (100 μg NP/L was toxic to the fish). We also demonstrate that our construct works in medaka, another model fish test species, suggesting the transient assay is applicable for testing oestrogenic chemicals in fish generally. Conclusion Our results indicate that the transient expression assay system can be used as a rapid integrated testing system for environmental oestrogens and to detect the oestrogenic target sites in developing fish embryos. PMID:22726887
Ruocco, Gaetano; Nuti, Ranuccio; Giambelluca, Amalia; Evangelista, Isabella; De Vivo, Oreste; Daniello, Cosimo; Palazzuoli, Alberto
2017-11-01
Worsening renal function (WRF) occurs in one-third of patients hospitalized for acute decompensated heart failure. Recently, WRF was categorized in two subtypes: persistent and transient WRF. Thus, we sought to investigate the different prognostic impact of persistent vs. transient WRF; we also evaluate the relation of two WRF phenotypes with congestion, B-type natriuretic peptide (BNP) changes, and diuretic response at discharge. The prospective was a single centre study including patients screened for interventional Diur-heart failure Trial (NCT01441245). Patients were eligible if they were admitted with a primary diagnosis of acute heart failure with evidence of volume overload. Persistent WRF was defined as a sustained creatinine increase by at least 0.3 mg/dl throughout the hospitalisation; transient WRF was defined as creatinine increase by at least 0.3 mg/dl within 72 h and a return to baseline levels at discharge. Patients were followed for 6 months after discharge. Our population included 192 acute decompensated heart failure patients. In total, 61 patients developed persistent WRF and 29 developed transient WRF. Patients with persistent WRF showed a lower mean urine output with respect to the transient WRF group and patients with preserved renal function (1618 ± 374 vs. 2132 ± 392 vs. 2075 ± 442 ml; P < 0.001). Similarly, patients with transient WRF demonstrated a higher rate of BNP decrease more than 30% than seen in patients with stable creatinine levels and in the persistent WRF group (95 vs. 76 vs. 54%; P = 0.001). Univariate Cox regression analysis demonstrated that BNP decrease less than 30% [HR 2.15 (1.40-3.40); P < 0.001] and persistent WRF [HR 1.70 (1.11-2.61); P = 0.01] were related to poor outcome; conversely, transient WRF should be considered as a protective factor [HR 0.42 (0.19-0.93); P = 0.03]. In the multivariable model, only persistent WRF appeared to be related to poor prognosis [HR 1.61 (1.02-2.57); P = 0.04]. WRF occurring during hospitalization has a different significance: transient deterioration appears to be associated with a favourable clinical course; conversely, persistent WRF is related to poor outcome.
Bazzazi, Hojjat; Sang, Lingjie; Dick, Ivy E; Joshi-Mukherjee, Rosy; Yang, Wanjun; Yue, David T
2015-01-01
Abstract The phosphatase calcineurin is a central component of many calcium signalling pathways, relaying calcium signals from the plasma membrane to the nucleus. It has critical functions in a multitude of systems, including immune, cardiac and neuronal. Given the widespread importance of calcineurin in both normal and pathological conditions, new tools that elucidate the spatiotemporal dynamics of calcineurin activity would be invaluable. Here we develop two separate genetically encoded fluorescence resonance energy transfer (FRET)-based sensors of calcineurin activation, DuoCaN and UniCaN. Both sensors showcase a large dynamic range and rapid response kinetics, differing primarily in the linker structure between the FRET pairs. Both sensors were calibrated in HEK293 cells and their responses correlated well with NFAT translocation to the nucleus, validating the biological relevance of the sensor readout. The sensors were subsequently expressed in neonatal rat ventricular myocytes and acutely isolated adult guinea pig ventricular myocytes. Both sensors demonstrated robust responses in myocytes and revealed kinetic differences in calcineurin activation during changes in pacing rate for neonatal versus adult myocytes. Finally, mathematical modelling combined with quantitative FRET measurements provided novel insights into the kinetics and integration of calcineurin activation in response to myocyte Ca transients. In all, DuoCaN and UniCaN stand as valuable new tools for understanding the role of calcineurin in normal and pathological signalling. Key points Novel fluorescence resonance energy transfer-based genetically encoded reporters of calcineurin are constructed by fusing the two subunits of calcineurin with P2A-based linkers retaining the expected native conformation of calcineurin. Calcineurin reporters display robust responses to calcium transients in HEK293 cells. The sensor responses are correlated with NFATc1 translocation dynamics in HEK293 cells. The sensors are uniformly distributed in neonatal myocytes and respond efficiently to single electrically evoked calcium transients and show cumulative activation at frequencies of 0.5 and 1 Hz. In adult myocytes, the calcineurin sensors appear to be localized to the cardiac z-lines, and respond to cumulative calcium transients at frequencies of 0.5 and 1 Hz. PMID:26096996
Transient and Dynamic Stability Analysis | Grid Modernization | NREL
are investigating the impact of high penetrations of wind and solar power on the frequency response ) Transient Stability and Frequency Response of the US Western Interconnection under Conditions of High Wind Subcontract Report (2013) Frequency Response of the US Eastern Interconnection under Condition of High Wind
NASA Astrophysics Data System (ADS)
Demir, Ozgur; Sahin, Abdurrahman; Yilmaz, Tamer
2012-09-01
Underwater explosion induced shock loads are capable of causing considerable structural damage. Investigations of the underwater explosion (UNDEX) effects on structures have seen continuous developments because of security risks. Most of the earlier experimental investigations were performed by military since the World War I. Subsequently; Cole [1] established mathematical relations for modeling underwater explosion shock loading, which were the outcome of many experimental investigations This study predicts and establishes the transient responses of a panel structure to underwater explosion shock loads using non-linear finite element code Ls-Dyna. Accordingly, in this study a new MATLAB code has been developed for predicting shock loading profile for different weight of explosive and different shock factors. Numerical analysis was performed for various test conditions and results are compared with Ramajeyathilagam's experimental study [8].
Recent Applications of Higher-Order Spectral Analysis to Nonlinear Aeroelastic Phenomena
NASA Technical Reports Server (NTRS)
Silva, Walter A.; Hajj, Muhammad R.; Dunn, Shane; Strganac, Thomas W.; Powers, Edward J.; Stearman, Ronald
2005-01-01
Recent applications of higher-order spectral (HOS) methods to nonlinear aeroelastic phenomena are presented. Applications include the analysis of data from a simulated nonlinear pitch and plunge apparatus and from F-18 flight flutter tests. A MATLAB model of the Texas A&MUniversity s Nonlinear Aeroelastic Testbed Apparatus (NATA) is used to generate aeroelastic transients at various conditions including limit cycle oscillations (LCO). The Gaussian or non-Gaussian nature of the transients is investigated, related to HOS methods, and used to identify levels of increasing nonlinear aeroelastic response. Royal Australian Air Force (RAAF) F/A-18 flight flutter test data is presented and analyzed. The data includes high-quality measurements of forced responses and LCO phenomena. Standard power spectral density (PSD) techniques and HOS methods are applied to the data and presented. The goal of this research is to develop methods that can identify the onset of nonlinear aeroelastic phenomena, such as LCO, during flutter testing.
NASA Technical Reports Server (NTRS)
Boland, J. S., III
1973-01-01
The derivation of an approximate error characteristic equation describing the transient system error response is given, along with a procedure for selecting adaptive gain parameters so as to relate to the transient error response. A detailed example of the application and implementation of these methods for a space shuttle type vehicle is included. An extension of the characteristic equation technique is used to provide an estimate of the magnitude of the maximum system error and an estimate of the time of occurrence of this maximum after a plant parameter disturbance. Techniques for relaxing certain stability requirements and the conditions under which this can be done and still guarantee asymptotic stability of the system error are discussed. Such conditions are possible because the Lyapunov methods used in the stability derivation allow for overconstraining a problem in the process of insuring stability.
Transient thermal stresses of work roll by coupled thermoelasticity
NASA Astrophysics Data System (ADS)
Lai, W. B.; Chen, T. C.; Weng, C. I.
1991-01-01
A numerical method, based on a two-dimensional plane strain model, is developed to predict the transient responses (that include distributions of temperature, thermal deformation, and thermal stress) of work roll during strip rolling by coupled thermoelasticity. The method consists of discretizing the space domain of the problem by finite element method first, and then treating the time domain by implicit time integration techniques. In order to avoid the difficulty in analysis due to relative movement between work roll and its thermal boundary, the energy equation is formulated with respect to a fixed Eulerian reference frame. The effect of thermoelastic coupling term, that is generally disregarded in strip rolling, can be considered and assessed. The influences of some important process parameters, such as rotational speed of the roll and intensity of heat flux, on transient solutions are also included and discussed. Furthermore, since the stress history at any point of the roll in both transient and steady state could be accurately evaluated, it is available to perform the analysis of thermal fatigue for the roll by means of previous data.
Benzodiazepine temazepam suppresses the transient auditory 40-Hz response amplitude in humans.
Jääskeläinen, I P; Hirvonen, J; Saher, M; Pekkonen, E; Sillanaukee, P; Näätänen, R; Tiitinen, H
1999-06-18
To discern the role of the GABA(A) receptors in the generation and attentive modulation of the transient auditory 40-Hz response, the effects of the benzodiazepine temazepam (10 mg) were studied in 10 healthy social drinkers, using a double-blind placebo-controlled design. Three hundred Hertz standard and 330 Hz rare deviant tones were presented to the left, and 1000 Hz standards and 1100 Hz deviants to the right ear of the subjects. Subjects attended to a designated ear and were to detect deviants therein while ignoring tones to the other. Temazepam significantly suppressed the amplitude of the 40-Hz response, the effect being equal for attended and non-attended tone responses. This suggests involvement of GABA(A) receptors in transient auditory 40-Hz response generation, however, not in the attentive modulation of the 40-Hz response.
Identification of quasi-steady compressor characteristics from transient data
NASA Technical Reports Server (NTRS)
Nunes, K. B.; Rock, S. M.
1984-01-01
The principal goal was to demonstrate that nonlinear compressor map parameters, which govern an in-stall response, can be identified from test data using parameter identification techniques. The tasks included developing and then applying an identification procedure to data generated by NASA LeRC on a hybrid computer. Two levels of model detail were employed. First was a lumped compressor rig model; second was a simplified turbofan model. The main outputs are the tools and procedures generated to accomplish the identification.
NASA Astrophysics Data System (ADS)
Avigo, I.; Cortés, R.; Rettig, L.; Thirupathaiah, S.; Jeevan, H. S.; Gegenwart, P.; Wolf, T.; Ligges, M.; Wolf, M.; Fink, J.; Bovensiepen, U.
2013-03-01
We employed femtosecond time- and angle-resolved photoelectron spectroscopy to analyze the response of the electronic structure of the 122 Fe-pnictide parent compounds Ba/EuFe2As2 and optimally doped BaFe1.85Co0.15As2 near the Γ point to optical excitation by an infrared femtosecond laser pulse. We identify pronounced changes of the electron population within several 100 meV above and below the Fermi level, which we explain as a combination of (i) coherent lattice vibrations, (ii) a hot electron and hole distribution, and (iii) transient modifications of the chemical potential. The responses of the three different materials are very similar. In the coherent response we identify three modes at 5.6, 3.3, and 2.6 THz. While the highest frequency mode is safely assigned to the A1g mode, the other two modes require a discussion in comparison to the literature. Employing a transient three temperature model we deduce from the transient evolution of the electron distribution a rather weak, momentum-averaged electron-phonon coupling quantified by values for λ<ω2> between 30 and 70 meV2. The chemical potential is found to present pronounced transient changes reaching a maximum of 15 meV about 0.6 ps after optical excitation and is modulated by the coherent phonons. This change in the chemical potential is particularly strong in a multiband system like the 122 Fe-pnictide compounds investigated here due to the pronounced variation of the electron density of states close to the equilibrium chemical potential.
NASA Astrophysics Data System (ADS)
Momox, Ernesto; Zakhleniuk, Nick; Balkan, Naci
2012-11-01
A detailed study of high-field transient and direct-current (DC) transport in GaN-based Gunn diode oscillators is carried out using the commercial simulator Sentaurus Device. Applicability of drift-diffusion (DD) and hydrodynamic (HD) models to high-speed, high-frequency devices is discussed in depth, and the results of the simulations from these models are compared. It is shown, for a highly homogeneous device based on a short (2 μm) supercritically doped (1017 cm-3) GaN specimen, that the DD model is unable to correctly take into account some essential physical effects which determine the operation mode of the device. At the same time, the HD model is ideally suited to solve such problems due to its ability to incorporate non-local effects. We show that the velocity overshoot near the device contacts and space charge injection and extraction play a crucial role in defining the operation mode of highly homogeneous short diodes in both the transient regime and the voltage-controlled oscillation regime. The transient conduction current responses are fundamentally different in the DD and HD models. The DD current simply repeats the velocity-field (v-F) characteristics, and the sample remains in a completely homogeneous state. In the HD model, the transient current pulse with a full width at half maximum of approximately 0.2 ps is increased about twofold due to the carrier injection (extraction) into (from) the active region and the velocity overshoot. The electron gas is characterized by highly inhomogeneous distributions of the carrier density, the electric field and the electron temperature. The simulation of the DC steady states of the diodes also shows very different results for the two models. The HD model shows the trapped stable anodic domain in the device, while the DD model completely retains all features of the v-F characteristics in a homogeneous gas. Simulation of the voltage-controlled oscillator shows that it operates in the accumulation layer mode generating microwave signals at 0.3 to 0.7 THz. In spite of the fact that the known criterion of a Gunn domain mode n 0 L > ( n 0 L)0 was satisfied, no Gunn domains were observed. The explanation of this phenomenon is given.
NASA Astrophysics Data System (ADS)
Scarlat, Raluca Olga
This dissertation treats system design, modeling of transient system response, and characterization of individual phenomena and demonstrates a framework for integration of these three activities early in the design process of a complex engineered system. A system analysis framework for prioritization of experiments, modeling, and development of detailed design is proposed. Two fundamental topics in thermal-hydraulics are discussed, which illustrate the integration of modeling and experimentation with nuclear reactor design and safety analysis: thermal-hydraulic modeling of heat generating pebble bed cores, and scaled experiments for natural circulation heat removal with Boussinesq liquids. The case studies used in this dissertation are derived from the design and safety analysis of a pebble bed fluoride salt cooled high temperature nuclear reactor (PB-FHR), currently under development in the United States at the university and national laboratories level. In the context of the phenomena identification and ranking table (PIRT) methodology, new tools and approaches are proposed and demonstrated here, which are specifically relevant to technology in the early stages of development, and to analysis of passive safety features. A system decomposition approach is proposed. Definition of system functional requirements complements identification and compilation of the current knowledge base for the behavior of the system. Two new graphical tools are developed for ranking of phenomena importance: a phenomena ranking map, and a phenomena identification and ranking matrix (PIRM). The functional requirements established through this methodology were used for the design and optimization of the reactor core, and for the transient analysis and design of the passive natural circulation driven decay heat removal system for the PB-FHR. A numerical modeling approach for heat-generating porous media, with multi-dimensional fluid flow is presented. The application of this modeling approach to the PB-FHR annular pebble bed core cooled by fluoride salt mixtures generated a model that is called Pod. Pod. was used to show the resilience of the PB-FHR core to generation of hot spots or cold spots, due to the effect of buoyancy on the flow and temperature distribution in the packed bed. Pod. was used to investigate the PB-FHR response to ATWS transients. Based on the functional requirements for the core, Pod. was used to generate an optimized design of the flow distribution in the core. An analysis of natural circulation loops cooled by single-phase Boussinesq fluids is presented here, in the context of reactor design that relies on natural circulation decay heat removal, and design of scaled experiments. The scaling arguments are established for a transient natural circulation loop, for loops that have long fluid residence time, and negligible contribution of fluid inertia to the momentum equation. The design of integral effects tests for the loss of forced circulation (LOFC) for PB-FHR is discussed. The special case of natural circulation decay heat removal from a pebble bed reactor was analyzed. A way to define the Reynolds number in a multi-dimensional pebble bed was identified. The scaling methodology for replicating pebble bed friction losses using an electrically resistance heated annular pipe and a needle valve was developed. The thermophysical properties of liquid fluoride salts lead to design of systems with low flow velocities, and hence long fluid residence times. A comparison among liquid coolants for the performance of steady state natural circulation heat removal from a pebble bed was performed. Transient natural circulation experimental data with simulant fluids for fluoride salts is given here. The low flow velocity and the relatively high viscosity of the fluoride salts lead to low Reynolds number flows, and a low Reynolds number in conjunction with a sufficiently high coefficient of thermal expansion makes the system susceptible to local buoyancy effects Experiments indicate that slow exchange of stagnant fluid in static legs can play a significant role in the transient response of natural circulation loops. The effect of non-linear temperature profiles on the hot or cold legs or other segments of the flow loop, which may develop during transient scenarios, should be considered when modeling the performance of natural circulation loops. The data provided here can be used for validation of the application of thermal-hydraulic systems codes to the modeling of heat removal by natural circulation with liquid fluoride salts and its simulant fluids.
Experimental Validation of a Closed Brayton Cycle System Transient Simulation
NASA Technical Reports Server (NTRS)
Johnson, Paul K.; Hervol, David S.
2006-01-01
The Brayton Power Conversion Unit (BPCU) is a closed cycle system with an inert gas working fluid. It is located in Vacuum Facility 6 at NASA Glenn Research Center. Was used in previous solar dynamic technology efforts (SDGTD). Modified to its present configuration by replacing the solar receiver with an electrical resistance heater. The first closed-Brayton-cycle to be coupled with an ion propulsion system. Used to examine mechanical dynamic characteristics and responses. The focus of this work was the validation of a computer model of the BPCU. Model was built using the Closed Cycle System Simulation (CCSS) design and analysis tool. Test conditions were then duplicated in CCSS. Various steady-state points. Transients involving changes in shaft rotational speed and heat input. Testing to date has shown that the BPCU is able to generate meaningful, repeatable data that can be used for computer model validation. Results generated by CCSS demonstrated that the model sufficiently reproduced the thermal transients exhibited by the BPCU system. CCSS was also used to match BPCU steady-state operating points. Cycle temperatures were within 4.1% of the data (most were within 1%). Cycle pressures were all within 3.2%. Error in alternator power (as much as 13.5%) was attributed to uncertainties in the compressor and turbine maps and alternator and bearing loss models. The acquired understanding of the BPCU behavior gives useful insight for improvements to be made to the CCSS model as well as ideas for future testing and possible system modifications.
NASA Astrophysics Data System (ADS)
Dimastrodonato, Valeria; Pelucchi, Emanuele; Zestanakis, Panagiotis A.; Vvedensky, Dimitri D.
2013-07-01
We present a theoretical model of the formation of self-limited (Al)GaAs quantum wires within V-grooves on GaAs(001) substrates during metalorganic vapor-phase epitaxy. We identify the facet-dependent rates of the kinetic processes responsible for the formation of the self-limiting profile, which is accompanied by Ga segregation along the axis perpendicular to the bottom of the original template, and analyze their interplay with the facet geometry in the transient regime. A reduced model is adopted for the evolution of the patterned profile, as determined by the angle between the different crystallographic planes as a function of the growth conditions. Our results provide a comprehensive phenomenological understanding of the self-ordering mechanism on patterned surfaces which can be harnessed for designing the quantum optical properties of low-dimensional systems.
Convergence of finite difference transient response computations for thin shells.
NASA Technical Reports Server (NTRS)
Sobel, L. H.; Geers, T. L.
1973-01-01
Numerical studies pertaining to the limits of applicability of the finite difference method in the solution of linear transient shell response problems are performed, and a computational procedure for the use of the method is recommended. It is found that the only inherent limitation of the finite difference method is its inability to reproduce accurately response discontinuities. This is not a serious limitation in view of natural constraints imposed by the extension of Saint Venant's principle to transient response problems. It is also found that the short wavelength limitations of thin shell (Bernoulli-Euler) theory create significant convergence difficulties in computed response to certain types of transverse excitations. These difficulties may be overcome, however, through proper selection of finite difference mesh dimensions and temporal smoothing of the excitation.
Tilles, Paulo F C; Petrovskii, Sergei V
2016-07-01
Patterns of individual animal movement have been a focus of considerable attention recently. Of particular interest is a question how different macroscopic properties of animal dispersal result from the stochastic processes occurring on the microscale of the individual behavior. In this paper, we perform a comprehensive analytical study of a model where the animal changes the movement velocity as a result of its behavioral response to environmental stochasticity. The stochasticity is assumed to manifest itself through certain signals, and the animal modifies its velocity as a response to the signals. We consider two different cases, i.e. where the change in the velocity is or is not correlated to its current value. We show that in both cases the early, transient stage of the animal movement is super-diffusive, i.e. ballistic. The large-time asymptotic behavior appears to be diffusive in the uncorrelated case but super-ballistic in the correlated case. We also calculate analytically the dispersal kernel of the movement and show that, whilst it converge to a normal distribution in the large-time limit, it possesses a fatter tail during the transient stage, i.e. at early and intermediate time. Since the transients are known to be highly relevant in ecology, our findings may indicate that the fat tails and superdiffusive spread that are sometimes observed in the movement data may be a feature of the transitional dynamics rather than an inherent property of the animal movement.
NASA Technical Reports Server (NTRS)
Mahan, J. R.; Tira, N. E.; Lee, Robert B., III; Keynton, R. J.
1989-01-01
The Earth Radiation Budget Experiment consists of an array of radiometric instruments placed in earth orbit by the National Aeronautics and Space Administration to monitor the longwave and visible components of the earth's radiation budget. Presented is a dynamic electrothermal model of the active cavity radiometer used to measure the earth's total radiative exitance. Radiative exchange is modeled using the Monte Carlo method and transient conduction is treated using the finite element method. Also included is the feedback circuit which controls electrical substitution heating of the cavity. The model is shown to accurately predict the dynamic response of the instrument during solar calibration.
NASA Technical Reports Server (NTRS)
Wilson, Jeffrey D.; Zimmerli, Gregory A.
2012-01-01
Good antenna-mode coupling is needed for determining the amount of propellant in a tank through the method of radio frequency mass gauging (RFMG). The antenna configuration and position in a tank are important factors in coupling the antenna to the natural electromagnetic modes. In this study, different monopole and dipole antenna mounting configurations and positions were modeled and responses simulated in a full-scale tank model with the transient solver of CST Microwave Studio (CST Computer Simulation Technology of America, Inc.). The study was undertaken to qualitatively understand the effect of antenna design and placement within a tank on the resulting radio frequency (RF) tank spectrum.
Combustor liner durability analysis
NASA Technical Reports Server (NTRS)
Moreno, V.
1981-01-01
An 18 month combustor liner durability analysis program was conducted to evaluate the use of advanced three dimensional transient heat transfer and nonlinear stress-strain analyses for modeling the cyclic thermomechanical response of a simulated combustor liner specimen. Cyclic life prediction technology for creep/fatigue interaction is evaluated for a variety of state-of-the-art tools for crack initiation and propagation. The sensitivity of the initiation models to a change in the operating conditions is also assessed.
The Shock and Vibration Digest. Volume 18, Number 9
1986-09-01
microprocessors. ods for mobility measurements, methods for Modeling and computation of transient rotor analyzing mobility data, mathematical modeling...behavior and nonlinear fluid-film bearing from mobility data, and applications of modal behavior will be described. Sessions will be test results will be...Zoned Viscoelastic Analysis of the Response of Dams to Earth- soil, quakesR. Abascal, J. Dominguez V. Lotfi , N6 445 • . , .-e ’SJ. PP %-’ , Ph.D. Thesis
Valentino, Francesco; Beccari, Mario; Villano, Marianna; Tandoi, Valter; Majone, Mauro
2017-05-25
A pure culture of the filamentous bacterium Thiothrix, strain CT3, was aerobically cultured in a chemostat under continuous acetate feeding at three different culture residence times (RT 6, 12 or 22 d) and the same volumetric organic load rate (OLR 0.12gCOD/L/d). Cells cultured at decreasing RT in the chemostat had an increasing transient response to acetate spikes in batch tests. The maximum specific acetate removal rate increased from 25 to 185mgCOD/gCOD/h, corresponding to a 1.8 to 8.1 fold higher respective steady-state rate in the chemostat. The transient response was mainly due to acetate storage in the form of poly(3-hydroxybutyrate) (PHB), whereas no growth response was observed at any RT. Interestingly, even though the storage rate also decreased as the RT increased, the storage yield increased from 0.41 to 0.50 COD/COD. This finding does not support the traditional view that storage plays a more important role as the transient response increases. The transient response of the steady-state cells was much lower than in cells cultured under periodic feeding (at 6 d RT, from 82 to 247mgCOD/gCOD/h), with the latter cells showing both storage and growth responses. On the other hand, even though steady-state cells had no growth response and their storage rate was also less, steady-state cells showed a higher storage yield than cells cultured under dynamic feeding. This suggests that in Thiothrix strain CT3, the growth response is triggered by periodic feeding, whereas the storage response is a constitutive mechanism, independent from previous acclimation to transient conditions. Copyright © 2016 Elsevier B.V. All rights reserved.
Experimental Study of Hydraulic Systems Transient Response Characteristics
1978-12-01
of Filter .. ... ...... ..... ..... 28 Effects of Quincke -Tube. .. ..... ...... ... 28 Error ’Estimation. .. ... ...... ..... ..... 33 I. CONCLUSIONS...System With Quincke -Tube i Configuration ..... ..................... ... 11 6 Schematic of Pump System .... ............... ... 12 7 Example of Computer...Filter Configuration ........ ..................... 32 20 Transient Response, Reservoir System, Quincke -Tube (Short) Configuration, 505 PSIA
NASA Astrophysics Data System (ADS)
Wu, Q.; Yao, Y.; Liu, S.
2017-12-01
The impact of the Eurasian snow cover extent (SCE) on the Northern Hemisphere (NH) circulation is first investigated by applying a lagged maximum covariance analysis (MCA) to monthly satellite-derived SCE and NCEP reanalysis data. Wintertime atmospheric signals significantly correlated with persistently autumn-early winter SCE anomalies are found in the leading two MCA modes. The first MCA mode indicates the effect of Eurasian snow cover anomalies on the Arctic Oscillation/North Atlantic Oscillation (AO/NAO). The second MCA mode links a persistent dipole of autumn and winter SCE anomalies over the Tibetan Plateau (TP) and Mongolia with winter Pacific-North America (PNA)-like atmospheric variations. A modeling study further investigates atmospheric responses to above TP and Mongolia snow forcings using multiple ensemble transient integrations of the CAM4 and CLM4.0 models. Model boundary conditions are based on climatological sea ice extent (SIE) and sea surface temperature (SST), and satellite observations of SCE and snow water equivalent (SWE) over the TP and Mongolia from October to March in 1997/98 (heavy TP and light Mongolia snow) and 1984/85 (light TP and heavy Mongolia snow), with model derived SCE and SWE elsewhere. In various forcing experiments, the ensemble-mean difference between simulations with these two extreme snow states identifies local, distant, concurrent, and delayed climatic responses. The main atmospheric responses to a dipole of high TP and low Mongolia SCE persisting from October to March (versus the opposite extreme) are strong TP surface cooling, warming in the surrounding China and Mongolia region, and a winter positive PNA-like response. The localized response is maintained by persistent diabatic cooling or heating, and the remote PNA response results mainly from the increased horizontal eastward propagation of stationary Rossby wave energy due to persistent TP snow forcing and also a winter transient eddy feedback mechanism. With a less persistent dipole anomaly in autumn or winter only, local responses are similar depending on the specific anomalies, but the winter PNA-like response is nearly absent or noticeably reduced.
Force encoding in muscle spindles during stretch of passive muscle
Blum, Kyle P.; Zytnicki, Daniel
2017-01-01
Muscle spindle proprioceptive receptors play a primary role in encoding the effects of external mechanical perturbations to the body. During externally-imposed stretches of passive, i.e. electrically-quiescent, muscles, the instantaneous firing rates (IFRs) of muscle spindles are associated with characteristics of stretch such as length and velocity. However, even in passive muscle, there are history-dependent transients of muscle spindle firing that are not uniquely related to muscle length and velocity, nor reproduced by current muscle spindle models. These include acceleration-dependent initial bursts, increased dynamic response to stretch velocity if a muscle has been isometric, and rate relaxation, i.e., a decrease in tonic IFR when a muscle is held at a constant length after being stretched. We collected muscle spindle spike trains across a variety of muscle stretch kinematic conditions, including systematic changes in peak length, velocity, and acceleration. We demonstrate that muscle spindle primary afferents in passive muscle fire in direct relationship to muscle force-related variables, rather than length-related variables. Linear combinations of whole muscle-tendon force and the first time derivative of force (dF/dt) predict the entire time course of transient IFRs in muscle spindle Ia afferents during stretch (i.e., lengthening) of passive muscle, including the initial burst, the dynamic response to lengthening, and rate relaxation following lengthening. Similar to acceleration scaling found previously in postural responses to perturbations, initial burst amplitude scaled equally well to initial stretch acceleration or dF/dt, though later transients were only described by dF/dt. The transient increase in dF/dt at the onset of lengthening reflects muscle short-range stiffness due to cross-bridge dynamics. Our work demonstrates a critical role of muscle cross-bridge dynamics in history-dependent muscle spindle IFRs in passive muscle lengthening conditions relevant to the detection and sensorimotor response to mechanical perturbations to the body, and to previously-described history-dependence in perception of limb position. PMID:28945740
Force encoding in muscle spindles during stretch of passive muscle.
Blum, Kyle P; Lamotte D'Incamps, Boris; Zytnicki, Daniel; Ting, Lena H
2017-09-01
Muscle spindle proprioceptive receptors play a primary role in encoding the effects of external mechanical perturbations to the body. During externally-imposed stretches of passive, i.e. electrically-quiescent, muscles, the instantaneous firing rates (IFRs) of muscle spindles are associated with characteristics of stretch such as length and velocity. However, even in passive muscle, there are history-dependent transients of muscle spindle firing that are not uniquely related to muscle length and velocity, nor reproduced by current muscle spindle models. These include acceleration-dependent initial bursts, increased dynamic response to stretch velocity if a muscle has been isometric, and rate relaxation, i.e., a decrease in tonic IFR when a muscle is held at a constant length after being stretched. We collected muscle spindle spike trains across a variety of muscle stretch kinematic conditions, including systematic changes in peak length, velocity, and acceleration. We demonstrate that muscle spindle primary afferents in passive muscle fire in direct relationship to muscle force-related variables, rather than length-related variables. Linear combinations of whole muscle-tendon force and the first time derivative of force (dF/dt) predict the entire time course of transient IFRs in muscle spindle Ia afferents during stretch (i.e., lengthening) of passive muscle, including the initial burst, the dynamic response to lengthening, and rate relaxation following lengthening. Similar to acceleration scaling found previously in postural responses to perturbations, initial burst amplitude scaled equally well to initial stretch acceleration or dF/dt, though later transients were only described by dF/dt. The transient increase in dF/dt at the onset of lengthening reflects muscle short-range stiffness due to cross-bridge dynamics. Our work demonstrates a critical role of muscle cross-bridge dynamics in history-dependent muscle spindle IFRs in passive muscle lengthening conditions relevant to the detection and sensorimotor response to mechanical perturbations to the body, and to previously-described history-dependence in perception of limb position.
The matrix exponential in transient structural analysis
NASA Technical Reports Server (NTRS)
Minnetyan, Levon
1987-01-01
The primary usefulness of the presented theory is in the ability to represent the effects of high frequency linear response with accuracy, without requiring very small time steps in the analysis of dynamic response. The matrix exponential contains a series approximation to the dynamic model. However, unlike the usual analysis procedure which truncates the high frequency response, the approximation in the exponential matrix solution is in the time domain. By truncating the series solution to the matrix exponential short, the solution is made inaccurate after a certain time. Yet, up to that time the solution is extremely accurate, including all high frequency effects. By taking finite time increments, the exponential matrix solution can compute the response very accurately. Use of the exponential matrix in structural dynamics is demonstrated by simulating the free vibration response of multi degree of freedom models of cantilever beams.
Flare Seismology from SDO Observations
NASA Astrophysics Data System (ADS)
Lindsey, Charles; Martinez Oliveros, Juan Carlos; Hudson, Hugh
2011-10-01
Some flares release intense seismic transients into the solar interior. These transients are the sole instance we know of in which the Sun's corona exerts a conspicuous influence on the solar interior through flares. The desire to understand this phenomenon has led to ambitious efforts to model the mechanisms by which energy stored in coronal magnetic fields drives acoustic waves that penetrate deep into the Sun's interior. These mechanisms potentially involve the hydrodynamic response of the chromosphere to thick-target heating by high-energy particles, radiative exchange in the chromosphere and photosphere, and Lorentz-force transients to account for acoustic energies estimated up to at 5X10^27 erg and momenta of order 6X10^19 dyne sec. An understanding of these components of flare mechanics promises more than a powerful diagnostic for local helioseismology. It could give us fundamental new insight into flare mechanics themselves. The key is appropriate observations to match the models. Helioseismic observations have identified the compact sources of transient seismic emission at the foot points of flares. The Solar Dynamics Observatory is now giving us high quality continuum-brightness and Doppler observations of acoustically active flares from HMI concurrent with high-resolution EUV observations from AIA. Supported by HXR observations from RHESSI and a broad variety of other observational resources, the SDO promises a leading role in flare research in solar cycle 24.
Cha, Chae Young; Nakamura, Yasuhiko; Himeno, Yukiko; Wang, JianWu; Fujimoto, Shinpei; Inagaki, Nobuya; Earm, Yung E
2011-01-01
To clarify the mechanisms underlying the pancreatic β-cell response to varying glucose concentrations ([G]), electrophysiological findings were integrated into a mathematical cell model. The Ca2+ dynamics of the endoplasmic reticulum (ER) were also improved. The model was validated by demonstrating quiescent potential, burst–interburst electrical events accompanied by Ca2+ transients, and continuous firing of action potentials over [G] ranges of 0–6, 7–18, and >19 mM, respectively. These responses to glucose were completely reversible. The action potential, input impedance, and Ca2+ transients were in good agreement with experimental measurements. The ionic mechanisms underlying the burst–interburst rhythm were investigated by lead potential analysis, which quantified the contributions of individual current components. This analysis demonstrated that slow potential changes during the interburst period were attributable to modifications of ion channels or transporters by intracellular ions and/or metabolites to different degrees depending on [G]. The predominant role of adenosine triphosphate–sensitive K+ current in switching on and off the repetitive firing of action potentials at 8 mM [G] was taken over at a higher [G] by Ca2+- or Na+-dependent currents, which were generated by the plasma membrane Ca2+ pump, Na+/K+ pump, Na+/Ca2+ exchanger, and TRPM channel. Accumulation and release of Ca2+ by the ER also had a strong influence on the slow electrical rhythm. We conclude that the present mathematical model is useful for quantifying the role of individual functional components in the whole cell responses based on experimental findings. PMID:21708953
NASA Technical Reports Server (NTRS)
Ambur, Damodar R.; Starnes, James H., Jr.; Prasad, Chunchu B.
1993-01-01
An analytical procedure is presented for determining the transient response of simply supported, rectangular laminated composite plates subjected to impact loads from airgun-propelled or dropped-weight impactors. A first-order shear-deformation theory is included in the analysis to represent properly any local short-wave-length transient bending response. The impact force is modeled as a locally distributed load with a cosine-cosine distribution. A double Fourier series expansion and the Timoshenko small-increment method are used to determine the contact force, out-of-plane deflections, and in-plane strains and stresses at any plate location due to an impact force at any plate location. The results of experimental and analytical studies are compared for quasi-isotropic laminates. The results indicate that using the appropriate local force distribution for the locally loaded area and including transverse-shear-deformation effects in the laminated plate response analysis are important. The applicability of the present analytical procedure based on small deformation theory is investigated by comparing analytical and experimental results for combinations of quasi-isotropic laminate thicknesses and impact energy levels. The results of this study indicate that large-deformation effects influence the response of both 24- and 32-ply laminated plates, and that a geometrically nonlinear analysis is required for predicting the response accurately.
NASA Astrophysics Data System (ADS)
Liu, Fei; Tong, Huan; Ma, Rui; Ou-Yang, Zhong-can
2010-12-01
A formal apparatus is developed to unify derivations of the linear response theory and a variety of transient fluctuation relations for continuous diffusion processes from a backward point of view. The basis is a perturbed Kolmogorov backward equation and the path integral representation of its solution. We find that these exact transient relations could be interpreted as a consequence of a generalized Chapman-Kolmogorov equation, which intrinsically arises from the Markovian characteristic of diffusion processes.
Diffenbaugh, Noah S.; Ashfaq, Moetasim; Scherer, Martin
2013-01-01
Integrating the potential for climate change impacts into policy and planning decisions requires quantification of the emergence of sub-regional climate changes that could occur in response to transient changes in global radiative forcing. Here we report results from a high-resolution, century-scale, ensemble simulation of climate in the United States, forced by atmospheric constituent concentrations from the Special Report on Emissions Scenarios (SRES) A1B scenario. We find that 21st century summer warming permanently emerges beyond the baseline decadal-scale variability prior to 2020 over most areas of the continental U.S. Permanent emergence beyond the baseline annual-scale variability shows much greater spatial heterogeneity, with emergence occurring prior to 2030 over areas of the southwestern U.S., but not prior to the end of the 21st century over much of the southcentral and southeastern U.S. The pattern of emergence of robust summer warming contrasts with the pattern of summer warming magnitude, which is greatest over the central U.S. and smallest over the western U.S. In addition to stronger warming, the central U.S. also exhibits stronger coupling of changes in surface air temperature, precipitation, and moisture and energy fluxes, along with changes in atmospheric circulation towards increased anticylonic anomalies in the mid-troposphere and a poleward shift in the mid-latitude jet aloft. However, as a fraction of the baseline variability, the transient warming over the central U.S. is smaller than the warming over the southwestern or northeastern U.S., delaying the emergence of the warming signal over the central U.S. Our comparisons with observations and the Coupled Model Intercomparison Project Phase 3 (CMIP3) ensemble of global climate model experiments suggest that near-term global warming is likely to cause robust sub-regional-scale warming over areas that exhibit relatively little baseline variability. In contrast, where there is greater variability in the baseline climate dynamics, there can be greater variability in the response to elevated greenhouse forcing, decreasing the robustness of the transient warming signal. PMID:24307747
Time-domain electromagnetic tests in the Wadi Bidah District, Kingdom of Saudi Arabia
Flanigan, Vincent J.; Sadek, Hamdy; Smith, Bruce; Tippens, C.L.
1983-01-01
A time-domain electromagnetic (TDEM) method was tested in two areas of mineralization in Precambrian rocks in the Wadi Bidah district, Kingdom of Saudi Arabia. Transient-decay voltages in profile mode were measured across the Sha'ab at Tare and Rabathan prospects by use of three transmitterreceiver loop configurations. At the Sha'ab at Tare prospect all of the loop configurations indicated the mineralized zone. Analysis of the coincident loop data at Sha'ab at Tare reveals that gossanous and altered rock of i0 ohm-m resistivity extends to a depth of 35 m, where there is an unweathered, dry mineralized zone of about 1 ohm-m resistivity. The model further suggests that the rocks at a depth of 55 m and below the water table are even less resistive (0. 1 ohm-m). The TDEM method successfully discriminated conductors within from those below the weathered zone at the Rabathan prospect. Conductors below the weathered zone are identified by a lack of transient response in the early part of the transient decay curve, followed by an increasing response in the middle to late parts of the transient decay curve. Results of these limited tests suggest the potential value of integrating TDEM with other geophysical tools in the Kingdom. Recommendations are made to expand these tests into a more comprehensive program that will evaluate the TDEM potential in various geologic environments that are host to mineral deposits of diverse origin.
NASA Astrophysics Data System (ADS)
Otsuka, Mioko; Hasegawa, Yasuhiro; Arisaka, Taichi; Shinozaki, Ryo; Morita, Hiroyuki
2017-11-01
The dimensionless figure of merit and its efficiency for the transient response of a Π-shaped thermoelectric module are estimated according to the theory of impedance spectroscopy. The effective dimensionless figure of merit is described as a function of the product of the characteristic time to reduce the temperature and the representative angular frequency of the module, which is expressed by the thermal diffusivity and the length of the elements used. The characteristic time required for achieving a higher dimensionless figure of merit and efficiency is derived quantitatively for the transient response using the properties of a commercial thermoelectric module.
On the Origin of Genres by Natural Selection: Inventing Genres Online.
ERIC Educational Resources Information Center
Hunt, Russell A.
The study of discourse genres as social action has steadily displaced more traditional views of genre, proposing the organic and ecological model that any consistent pattern of response to a recurrent rhetorical situation might constitute a genre. Observation of the life cycles of genres as transient social events can occur in a classroom using…
Dynamic responses of railroad car models to vertical and lateral rail inputs
NASA Technical Reports Server (NTRS)
Sewall, J. L.; Parrish, R. V.; Durling, B. J.
1971-01-01
Simplified dynamic models were applied in a study of vibration in a high-speed railroad car. The mathematical models used were a four-degree-of-freedom model for vertical responses to vertical rail inputs and a ten-degree-of-freedom model for lateral response to lateral or rolling (cross-level) inputs from the rails. Elastic properties of the passenger car body were represented by bending and torsion of a uniform beam. Rail-to-car (truck) suspensions were modeled as spring-mass-dashpot oscillators. Lateral spring nonlinearities approximating certain complicated truck mechanisms were introduced. The models were excited by displacement and, in some cases, velocity inputs from the rails by both deterministic (including sinusoidal) and random input functions. Results were obtained both in the frequency and time domains. Solutions in the time domain for the lateral model were obtained for a wide variety of transient and random inputs generated on-line by an analog computer. Variations in one of the damping properties of the lateral car suspension gave large fluctuations in response over a range of car speeds for a given input. This damping coefficient was significant in reducing lateral car responses that were higher for nonlinear springs for three different inputs.
NASA Astrophysics Data System (ADS)
Attal, M.; Tucker, G.; Whittaker, A.; Cowie, P.; Roberts, G.
2005-12-01
River systems constitute some of the most efficient agents that shape terrestrial landscapes. Fluvial incision rates govern landscape evolution but, due to the variety of processed involved and the difficulty of quantifying them in the field, there is no "universal theory" describing the way rivers incise into bedrock. The last decades have seen the birth of numerous fluvial incision laws associated with models that assign different roles to hydrodynamic variables and to sediments. In order to discriminate between models and constrain their parameters, the transient response of natural river systems to a disturbance (tectonic or climatic) can be used. Indeed, the different models predict different kinds of transient response whereas most models predict a similar power law relationship between slope and drainage area at equilibrium. To this end, a coupled field - modeling study is in progress. The field area consists of the Central Apennines that are subject to active faulting associated with a regional extensional regime. Fault initiation occurred 3 My ago, associated with throw rates of 0.3 +/- 0.2 mm/yr. Due to fault interaction and linkage, the throw rate on the faults located near the center of the fault system increased dramatically 0.7 My ago (up to 2 mm/yr), whereas slip rates on distal faults either decayed or remained approximately constant. The present study uses the landscape evolution model, CHILD, to examine the behavior of rivers draining across these active faults. Distal and central faults are considered in order to track the effects of the fault acceleration on the development of the fluvial network. River characteristics have been measured in the field (e.g. channel width, slope, sediment grain size) and extracted from a 20m DEM (e.g. channel profile, drainage area). We use CHILD to test the ability of alternative incision laws to reproduce observed topography under known tectonic forcing. For each of the fluvial incision models, a Monte-Carlo simulation has been performed, allowing the exploration of a wide range of values for the different parameters relative to tectonic, climate, sediment characteristics, and channel geometry. Observed profiles are consistent with a dominantly wave-like, as opposed to diffusive, transient response to accelerated fault motion. The ability of the different models to reproduce more or less accurately the catchment characteristics, in particular the specific profiles exhibited by the rivers, are discussed in light of our first results.
Relation of earphone transient response to measurement of onset-duration.
DOT National Transportation Integrated Search
1963-03-01
Measurements were made of the transient response of PDR-8 earphones. These data indicate that the original estimate of the onset-duration of auditory stimuli can be revised downward to 0.8 ms. Implicit in the results is a caveat on the faith one shou...
Identification of visual evoked response parameters sensitive to pilot mental state
NASA Technical Reports Server (NTRS)
Zacharias, G. L.
1988-01-01
Systems analysis techniques were developed and demonstrated for modeling the electroencephalographic (EEG) steady state visual evoked response (ssVER), for use in EEG data compression and as an indicator of mental workload. The study focused on steady state frequency domain stimulation and response analysis, implemented with a sum-of-sines (SOS) stimulus generator and an off-line describing function response analyzer. Three major tasks were conducted: (1) VER related systems identification material was reviewed; (2) Software for experiment control and data analysis was developed and implemented; and (3) ssVER identification and modeling was demonstrated, via a mental loading experiment. It was found that a systems approach to ssVER functional modeling can serve as the basis for eventual development of a mental workload indicator. The review showed how transient visual evoked response (tVER) and ssVER research are related at the functional level, the software development showed how systems techniques can be used for ssVER characterization, and the pilot experiment showed how a simple model can be used to capture the basic dynamic response of the ssVER, under varying loads.
Fast-Response Fiber-Optic Anemometer with Temperature Self-Compensation
2015-05-18
be considered to be a function of time only. With a heating source within the sensor, the model for LSA is expressed as [13], ( ) ( ),s w s s shA ... shA C Vρ , in the exponent of the transient term in RHS of Eq. (7) characterizes the response time of the anemometer. Conversion of the temperature...circulator, and the reflected signal night was acquired by a high-speed spectrometer (Ibsen Photonics, I-MON 256 USB) which was connected to a computer
Domain of validity of the perturbative approach to femtosecond optical spectroscopy
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gelin, Maxim F.; Rao, B. Jayachander; Nest, Mathias
2013-12-14
We have performed numerical nonperturbative simulations of transient absorption pump-probe responses for a series of molecular model systems. The resulting signals as a function of the laser field strength and the pump-probe delay time are compared with those obtained in the perturbative response function formalism. The simulations and their theoretical analysis indicate that the perturbative description remains valid up to moderately strong laser pulses, corresponding to a rather substantial depopulation (population) of the initial (final) electronic states.
Gene Expression and Structural Skeletal Responses to Long-Duration Simulated Microgravity in Rats
NASA Technical Reports Server (NTRS)
Shirazi-Fard, Yasaman; Rael, Victoria E.; Torres, Samantha; Steczina, Sonette; Bryant, Sheenah; Tahimic, Candice; Globus, Ruth K.
2017-01-01
In this study, we aim to examine skeletal responses to simulated long-duration spaceflight (90 days) and weight-bearing recovery on bone loss using the ground-based hindlimb unloading (HU) model in adolescent (3-month old) male rats. We hypothesized that simulated microgravity leads to the temporal regulation of oxidative defense genes and pro-bone resorption factors, where there is a progression and eventual plateau; furthermore, early transient changes in these pathways precede skeletal adaptations.
Analysis methods for Kevlar shield response to rotor fragments
NASA Technical Reports Server (NTRS)
Gerstle, J. H.
1977-01-01
Several empirical and analytical approaches to rotor burst shield sizing are compared and principal differences in metal and fabric dynamic behavior are discussed. The application of transient structural response computer programs to predict Kevlar containment limits is described. For preliminary shield sizing, present analytical methods are useful if insufficient test data for empirical modeling are available. To provide other information useful for engineering design, analytical methods require further developments in material characterization, failure criteria, loads definition, and post-impact fragment trajectory prediction.
Transient response of nonlinear polymer networks: A kinetic theory
NASA Astrophysics Data System (ADS)
Vernerey, Franck J.
2018-06-01
Dynamic networks are found in a majority of natural materials, but also in engineering materials, such as entangled polymers and physically cross-linked gels. Owing to their transient bond dynamics, these networks display a rich class of behaviors, from elasticity, rheology, self-healing, or growth. Although classical theories in rheology and mechanics have enabled us to characterize these materials, there is still a gap in our understanding on how individuals (i.e., the mechanics of each building blocks and its connection with others) affect the emerging response of the network. In this work, we introduce an alternative way to think about these networks from a statistical point of view. More specifically, a network is seen as a collection of individual polymer chains connected by weak bonds that can associate and dissociate over time. From the knowledge of these individual chains (elasticity, transient attachment, and detachment events), we construct a statistical description of the population and derive an evolution equation of their distribution based on applied deformation and their local interactions. We specifically concentrate on nonlinear elastic response that follows from the strain stiffening response of individual chains of finite size. Upon appropriate averaging operations and using a mean field approximation, we show that the distribution can be replaced by a so-called chain distribution tensor that is used to determine important macroscopic measures such as stress, energy storage and dissipation in the network. Prediction of the kinetic theory are then explored against known experimental measurement of polymer responses under uniaxial loading. It is found that even under the simplest assumptions of force-independent chain kinetics, the model is able to reproduce complex time-dependent behaviors of rubber and self-healing supramolecular polymers.
Analytical modeling of intumescent coating thermal protection system in a JP-5 fuel fire environment
NASA Technical Reports Server (NTRS)
Clark, K. J.; Shimizu, A. B.; Suchsland, K. E.; Moyer, C. B.
1974-01-01
The thermochemical response of Coating 313 when exposed to a fuel fire environment was studied to provide a tool for predicting the reaction time. The existing Aerotherm Charring Material Thermal Response and Ablation (CMA) computer program was modified to treat swelling materials. The modified code is now designated Aerotherm Transient Response of Intumescing Materials (TRIM) code. In addition, thermophysical property data for Coating 313 were analyzed and reduced for use in the TRIM code. An input data sensitivity study was performed, and performance tests of Coating 313/steel substrate models were carried out. The end product is a reliable computational model, the TRIM code, which was thoroughly validated for Coating 313. The tasks reported include: generation of input data, development of swell model and implementation in TRIM code, sensitivity study, acquisition of experimental data, comparisons of predictions with data, and predictions with intermediate insulation.
NASA Astrophysics Data System (ADS)
Hedman, Mojdeh Khorsand
After a major disturbance, the power system response is highly dependent on protection schemes and system dynamics. Improving power systems situational awareness requires proper and simultaneous modeling of both protection schemes and dynamic characteristics in power systems analysis tools. Historical information and ex-post analysis of blackouts reaffirm the critical role of protective devices in cascading events, thereby confirming the necessity to represent protective functions in transient stability studies. This dissertation is aimed at studying the importance of representing protective relays in power system dynamic studies. Although modeling all of the protective relays within transient stability studies may result in a better estimation of system behavior, representing, updating, and maintaining the protection system data becomes an insurmountable task. Inappropriate or outdated representation of the relays may result in incorrect assessment of the system behavior. This dissertation presents a systematic method to determine essential relays to be modeled in transient stability studies. The desired approach should identify protective relays that are critical for various operating conditions and contingencies. The results of the transient stability studies confirm that modeling only the identified critical protective relays is sufficient to capture system behavior for various operating conditions and precludes the need to model all of the protective relays. Moreover, this dissertation proposes a method that can be implemented to determine the appropriate location of out-of-step blocking relays. During unstable power swings, a generator or group of generators may accelerate or decelerate leading to voltage depression at the electrical center along with generator tripping. This voltage depression may cause protective relay mis-operation and unintentional separation of the system. In order to avoid unintentional islanding, the potentially mis-operating relays should be blocked from tripping with the use of out-of-step blocking schemes. Blocking these mis-operating relays, combined with an appropriate islanding scheme, help avoid a system wide collapse. The proposed method is tested on data from the Western Electricity Coordinating Council. A triple line outage of the California-Oregon Intertie is studied. The results show that the proposed method is able to successfully identify proper locations of out-of-step blocking scheme.
NASA Astrophysics Data System (ADS)
Matveev, A.; Matthews, H. D.
2009-04-01
Carbon fluxes from land conversion are among the most uncertain variables in our understanding of the contemporary carbon cycle, which limits our ability to estimate both the total human contribution to current climate forcing and the net effect of terrestrial biosphere changes on atmospheric CO2 increases. The current generation of coupled climate-carbon models have made significant progress in simulating the coupled climate and carbon cycle response to anthropogenic CO2 emissions, but do not typically include land-use change as a dynamic component of the simulation. In this work we have incorporated a book-keeping land-use carbon accounting model into the University of Victoria Earth System Climate Model (UVic ESCM), and intermediate-complexity coupled climate-carbon model. The terrestrial component of the UVic ESCM allows an aerial competition of five plant functional types (PFTs) in response to climatic conditions and area availability, and tracks the associated changes in affected carbon pools. In order to model CO2 emissions from land conversion in the terrestrial component of the model, we calculate the allocation of carbon to short and long-lived wood products following specified land-cover change, and use varying decay timescales to estimate CO2 emissions. We use recently available spatial datasets of both crop and pasture distributions to drive a series of transient simulations and estimate the net contribution of human land-use change to historical carbon emissions and climate change.
Some useful innovations with TRASYS and SINDA-85
NASA Technical Reports Server (NTRS)
Amundsen, Ruth M.
1993-01-01
Several innovative methods were used to allow more efficient and accurate thermal analysis using SINDA-85 and TRASYS, including model integration and reduction, planetary surface calculations, and model animation. Integration with other modeling and analysis codes allows an analyst to import a geometry from a solid modeling or computer-aided design (CAD) software package, rather than building the geometry 'by hand.' This is more efficient as well as potentially more accurate. However, the use of solid modeling software often generates large analytical models. The problem of reducing large models was elegantly solved using the response of the transient derivative to a forcing step function. The thermal analysis of a lunar rover implemented two unusual features of the TRASYS/SINDA system. A little-known TRASYS routine SURFP calculates the solar heating of a rover on the lunar surface for several different rover positions and orientations. This is used not only to determine the rover temperatures, but also to automatically determine the power generated by the solar arrays. The animation of transient thermal results is an effective tool, especially in a vivid case such as the 14-day progress of the sun over the lunar rover. An animated color map on the solid model displays the progression of temperatures.
On the time to steady state: insights from numerical modeling
NASA Astrophysics Data System (ADS)
Goren, L.; Willett, S.; McCoy, S. W.; Perron, J.
2013-12-01
How fast do fluvial landscapes approach steady state after an application of tectonic or climatic perturbation? While theory and some numerical models predict that the celerity of the advective wave (knickpoint) controls the response time for perturbations, experiments and other landscape evolution models demonstrate that the time to steady state is much longer than the theoretically predicted response time. We posit that the longevity of transient features and the time to steady state are controlled by the stability of the topology and geometry of channel networks. Evolution of a channel network occurs by a combination of discrete capture events and continuous migration of water divides, processes, which are difficult to represent accurately in landscape evolution models. We therefore address the question of the time to steady state using the DAC landscape evolution model that solves accurately for the location of water divides, using a combination of analytical solution for hillslopes and low-order channels together with a numerical solution for higher order channels. DAC also includes an explicit capture criterion. We have tested fundamental predictions from DAC and show that modeled networks reproduce natural network characteristics such as the Hack's exponent and coefficient and the fractal dimension. We define two steady-state criteria: a topographic steady state, defined by global, pointwise steady elevation, and a topological steady state defined as the state in which no further reorganization of the drainage network takes place. Analyzing block uplift simulations, we find that the time to achieve either topographic or topological steady state exceeds by an order of magnitude the theoretical response time of the fluvial network. The longevity of the transient state is the result of the area feedback, by which, migration of a divide changes the local contributing area. This change propagates downstream as a slope adjustment, forcing further divide migrations and area change in adjacent tributaries and basins. In order to characterize the evolution of the drainage network on its way to steady state, we define a proxy to steady state elevation, χ, which is also the characteristic parameter of the transient stream power PDE. Through simulations of tectonic tilting we find that reorganization tends to minimize moments of the χ distribution of the landscape and of Δχ across divides.
Thermo-mechanical concepts applied to modeling liquid propellant rocket engine stability
NASA Astrophysics Data System (ADS)
Kassoy, David R.; Norris, Adam
2016-11-01
The response of a gas to transient, spatially distributed energy addition can be quantified mathematically using thermo-mechanical concepts available in the literature. The modeling demonstrates that the ratio of the energy addition time scale to the acoustic time scale of the affected volume, and the quantity of energy added to that volume during the former determine the whether the responses to heating can be described as occurring at nearly constant volume, fully compressible or nearly constant pressure. Each of these categories is characterized by significantly different mechanical responses. Application to idealized configurations of liquid propellant rocket engines provides an opportunity to identify physical conditions compatible with gasdynamic disturbances that are sources of engine instability. Air Force Office of Scientific Research.
NASA Astrophysics Data System (ADS)
Gurnon, Amanda Kate
The complex, nonlinear flow behavior of soft materials transcends industrial applications, smart material design and non-equilibrium thermodynamics. A long-standing, fundamental challenge in soft-matter science is establishing a quantitative connection between the deformation field, local microstructure and macroscopic dynamic flow properties i.e., the rheology. Soft materials are widely used in consumer products and industrial processes including energy recovery, surfactants for personal healthcare (e.g. soap and shampoo), coatings, plastics, drug delivery, medical devices and therapeutics. Oftentimes, these materials are processed by, used during, or exposed to non-equilibrium conditions for which the transient response of the complex fluid is critical. As such, designing new dynamic experiments is imperative to testing these materials and further developing micromechanical models to predict their transient response. Two of the most common classes of these soft materials stand as the focus of the present research; they are: solutions of polymer-like micelles (PLM or also known as wormlike micelles, WLM) and concentrated colloidal suspensions. In addition to their varied applications these two different classes of soft materials are also governed by different physics. In contrast, to the shear thinning behavior of the WLMs at high shear rates, the near hard-sphere colloidal suspensions are known to display increases, sometimes quite substantial, in viscosity (known as shear thickening). The stress response of these complex fluids derive from the shear-induced microstructure, thus measurements of the microstructure under flow are critical for understanding the mechanisms underlying the complex, nonlinear rheology of these complex fluids. A popular micromechanical model is reframed from its original derivation for predicting steady shear rheology of polymers and WLMs to be applicable to weakly nonlinear oscillatory shear flow. The validity, utility and limits of this constitutive model are tested by comparison with experiments on model WLM solutions. Further comparisons to the nonlinear oscillatory shear responses measured from colloidal suspensions establishes this analysis as a promising, quantitative method for understanding the underlying mechanisms responsible for the nonlinear dynamic response of complex fluids. A new experimental technique is developed to measure the microstructure of complex fluids during steady and transient shear flow using small-angle neutron scattering (SANS). The Flow-SANS experimental method is now available to the broader user communities at the NIST Center for Neutron Research, Gaithersburg, MD and the Institut Laue-Langevin, Grenoble, France. Using this new method, a model shear banding WLM solution is interrogated under steady and oscillatory shear. For the first time, the flow-SANS methods identify new metastable states for shear banding WLM solutions, thus establishing the method as capable of probing new states not accessible using traditional steady or linear oscillatory shear methods. The flow-induced three-dimensional microstructure of a colloidal suspension under steady and dynamic oscillatory shear is also measured using these rheo- and flow-SANS methods. A new structure state is identified in the shear thickening regime that proves critical for defining the "hydrocluster" microstructure state of the suspension that is responsible for shear thickening. For both the suspensions and the WLM solutions, stress-SANS rules with the measured microstructures define the individual stress components arising separately from conservative and hydrodynamic forces and these are compared with the macroscopic rheology. Analysis of these results defines the crucial length- and time-scales of the transient microstructure response. The novel dynamic microstructural measurements presented in this dissertation provide new insights into the complexities of shear thickening and shear banding flow phenomena, which are effects observed more broadly across many different types of soft materials. Consequently, the microstructure-rheology property relationships developed for these two classes of complex fluids will aid in the testing and advancement of micromechanical constitutive model development, smart material design, industrial processing and fundamental non-equilibrium thermodynamic research of a broad range of soft materials.
Single Droplet Combustion of Decane in Microgravity: Experiments and Numerical Modeling
NASA Technical Reports Server (NTRS)
Dietrich, D. L.; Struk, P. M.; Ikegam, M.; Xu, G.
2004-01-01
This paper presents experimental data on single droplet combustion of decane in microgravity and compares the results to a numerical model. The primary independent experiment variables are the ambient pressure and oxygen mole fraction, pressure, droplet size (over a relatively small range) and ignition energy. The droplet history (D(sup 2) history) is non-linear with the burning rate constant increasing throughout the test. The average burning rate constant, consistent with classical theory, increased with increasing ambient oxygen mole fraction and was nearly independent of pressure, initial droplet size and ignition energy. The flame typically increased in size initially, and then decreased in size, in response to the shrinking droplet. The flame standoff increased linearly for the majority of the droplet lifetime. The flame surrounding the droplet extinguished at a finite droplet size at lower ambient pressures and an oxygen mole fraction of 0.15. The extinction droplet size increased with decreasing pressure. The model is transient and assumes spherical symmetry, constant thermo-physical properties (specific heat, thermal conductivity and species Lewis number) and single step chemistry. The model includes gas-phase radiative loss and a spherically symmetric, transient liquid phase. The model accurately predicts the droplet and flame histories of the experiments. Good agreement requires that the ignition in the experiment be reasonably approximated in the model and that the model accurately predict the pre-ignition vaporization of the droplet. The model does not accurately predict the dependence of extinction droplet diameter on pressure, a result of the simplified chemistry in the model. The transient flame behavior suggests the potential importance of fuel vapor accumulation. The model results, however, show that the fractional mass consumption rate of fuel in the flame relative to fuel vaporized is close to 1.0 for all but the lowest ambient oxygen mole fractions.
Design and calibration of a novel transient radiative heat flux meter for a spacecraft thermal test
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sheng, Chunchen; Hu, Peng, E-mail: hupeng@ustc.edu.cn; Cheng, Xiaofang
2016-06-15
Radiative heat flux measurement is significantly important for a spacecraft thermal test. To satisfy the requirements of both high accuracy and fast response, a novel transient radiative heat flux meter was developed. Its thermal receiver consists of a central thermal receiver and two thermal guarded annular plates, which ensure the temperature distribution of the central thermal receiver to be uniform enough for reasonably applying lumped heat capacity method in a transient radiative heat flux measurement. This novel transient radiative heat flux meter design can also take accurate measurements regardless of spacecraft surface temperature and incident radiation spectrum. The measurement principlemore » was elaborated and the coefficients were calibrated. Experimental results from testing a blackbody furnace and an Xenon lamp show that this novel transient radiative heat flux meter can be used to measure transient radiative heat flux up to 1400 W/m{sup 2} with high accuracy and the response time of less than 10 s.« less
A finite element program for postbuckling calculations (PSTBKL)
NASA Technical Reports Server (NTRS)
Simitses, G. T.; Carlson, R. L.; Riff, R.
1991-01-01
The object of the research reported herein was to develop a general mathematical model and solution methodologies for analyzing the structural response of thin, metallic shell structures under large transient, cyclic, or static thermochemical loads. This report describes the computer program resulting from the research. Among the system responses associated with these loads and conditions are thermal buckling, creep buckling, and ratcheting. Thus geometric and material nonlinearities (of high order) have been anticipated and are considered in developing the mathematical model. The methodology is demonstrated through different problems of extension, shear, and of planar curved beams. Moreover, importance of the inclusion of large strains is clearly demonstrated, through the chosen applications.
NASA Technical Reports Server (NTRS)
Simitses, George J.; Carlson, Robert L.; Riff, Richard
1991-01-01
The object of the research reported herein was to develop a general mathematical model and solution methodologies for analyzing the structural response of thin, metallic shell structures under large transient, cyclic, or static thermomechanical loads. Among the system responses associated with these loads and conditions are thermal buckling, creep buckling, and ratcheting. Thus geometric and material nonlinearities (of high order) can be anticipated and must be considered in developing the mathematical model. The methodology is demonstrated through different problems of extension, shear, and of planar curved beams. Moreover, importance of the inclusion of large strain is clearly demonstrated, through the chosen applications.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ito, Kota, E-mail: kotaito@mosk.tytlabs.co.jp; Nishikawa, Kazutaka; Iizuka, Hideo
Thermal information processing is attracting much interest as an analog of electronic computing. We experimentally demonstrated a radiative thermal memory utilizing a phase change material. The hysteretic metal-insulator transition of vanadium dioxide (VO{sub 2}) allows us to obtain a multilevel memory. We developed a Preisach model to explain the hysteretic radiative heat transfer between a VO{sub 2} film and a fused quartz substrate. The transient response of our memory predicted by the Preisach model agrees well with the measured response. Our multilevel thermal memory paves the way for thermal information processing as well as contactless thermal management.
Engineering an in vitro organotypic model for studying cardiac hypertrophy.
Jain, Aditi; Hasan, Jafar; Desingu, Perumal Arumugam; Sundaresan, Nagalingam R; Chatterjee, Kaushik
2018-05-01
Neonatal cardiomyocytes cultured on flat surfaces are commonly used as a model to study cardiac failure of diverse origin. A major drawback of such a system is that the cardiomyocytes do not exhibit alignment, organization and calcium transients, similar to the native heart. Therefore, there is a need to develop in vitro platforms that recapitulate the cellular microenvironment of the murine heart as organotypic models to study cardiovascular diseases. In this study, we report an engineered platform that mimics cardiac cell organization and function of the heart. For this purpose, microscale ridges were fabricated on silicon using ultraviolet lithography and reactive ion etching techniques. Physical characterization of the microstructures was done using scanning electron microscopy and atomic force microscopy. Cardiomyocytes grown on these micro-ridges showed global parallel alignment and elliptical nuclear morphology as observed in the heart. Interestingly, calcium currents traversed the engineered cardiomyocytes in a coordinated and directional manner. Moreover, the cardiomyocytes on the engineered substrates were found to be responsive to hypertrophic stimuli, as observed by the expression of a fetal gene, atrial natriuretic peptide and increase in calcium transients upon agonist treatment. Taken together, our work demonstrates that micro-ridges can be used to obtain cardiomyocyte response in vitro, which closely resembles mammalian heart. Copyright © 2018 Elsevier B.V. All rights reserved.
NASA Astrophysics Data System (ADS)
Herrera, María. S.; Monti Hughes, Andrea; Salva, Natalia; Padra, Claudio; Schwint, Amanda; Santa Cruz, Gustavo A.
2017-05-01
Biomedical infrared thermography, a non-invasive and functional imaging method, provides information on the normal and abnormal status and response of tissues in terms of spatial and temporal variations in body infrared radiance. It is especially attractive in cancer research due to the hypervascular and hypermetabolic activity of solid tumors. Moreover, healthy tissues like skin or mucosa exposed to radiation can be examined since inflammation, changes in water content, exudation, desquamation, erosion and necrosis, between others, are factors that modify their thermal properties. In this work we performed Dynamic Infrared Imaging (DIRI) to contribute to the understanding and evaluation of normal tissue, tumor and precancerous tissue response and radiotoxicity in an in vivo model, the hamster cheek pouch, exposed to Boron Neutron Capture Therapy. In this study, we particularly focused on the observation of temperature changes under forced transient conditions associated with mass moisture transfer in the tissue-air interface, in each tissue with or without treatment. We proposed a simple mathematical procedure that considerers the heat transfer from tissue to ambient through convection and evaporation to model the transient (exponential decay o recover) thermal study. The data was fitted to determined the characteristic decay and recovery time constants of the temperature as a function of time. Also this model allowed to explore the mass flux of moisture, as a degree of evaporation occurring on the tissue surface. Tissue thermal responses under provocation tests could be used as a non-invasive method to characterize tissue physiology.
Statistical analysis of modeling error in structural dynamic systems
NASA Technical Reports Server (NTRS)
Hasselman, T. K.; Chrostowski, J. D.
1990-01-01
The paper presents a generic statistical model of the (total) modeling error for conventional space structures in their launch configuration. Modeling error is defined as the difference between analytical prediction and experimental measurement. It is represented by the differences between predicted and measured real eigenvalues and eigenvectors. Comparisons are made between pre-test and post-test models. Total modeling error is then subdivided into measurement error, experimental error and 'pure' modeling error, and comparisons made between measurement error and total modeling error. The generic statistical model presented in this paper is based on the first four global (primary structure) modes of four different structures belonging to the generic category of Conventional Space Structures (specifically excluding large truss-type space structures). As such, it may be used to evaluate the uncertainty of predicted mode shapes and frequencies, sinusoidal response, or the transient response of other structures belonging to the same generic category.
Time and flow-direction responses of shear-styress-sensitive liquid crystal coatings
NASA Technical Reports Server (NTRS)
Reda, Daniel C.; Muraqtore, J. J.; Heinick, James T.
1994-01-01
Time and flow-direction responses of shear-stress liquid crystal coatings were exploresd experimentally. For the time-response experiments, coatings were exposed to transient, compressible flows created during the startup and off-design operation of an injector-driven supersonic wind tunnel. Flow transients were visualized with a focusing schlieren system and recorded with a 100 frame/s color video camera.
NASA Astrophysics Data System (ADS)
Ejiri, Arata; Sasaki, Jun; Kinoshita, Yusuke; Fujimoto, Junya; Maruyama, Tsugito; Shimotani, Keiji
For the purpose of contributing to global environment protection, several research studies have been conducted involving clean-burning diesel engines. In recent diesel engines with Exhaust Gas Recirculation (EGR) systems and a Variable Nozzle Turbocharger (VNT), mutual interference between EGR and VNT has been noted. Hence, designing and adjusting control of the conventional PID controller is particularly difficult at the transient state in which the engine speed and fuel injection rate change. In this paper, we formulate 1st principal model of air intake system of diesel engines and transform it to control oriented model including an engine steady state model and a transient model. And we propose a model-based control system with the LQR Controller, Saturation Compensator, the Dynamic Feed-forward and Disturbance Observer using a transient model. Using this method, we achieved precise reference tracking and emission reduction in transient mode test with the real engine evaluations.
Belugin, Sergei; Diogenes, Anibal R.; Patil, Mayur J.; Ginsburg, Erika; Henry, Michael A.; Akopian, Armen N.
2013-01-01
Prolactin (PRL) regulates activity of nociceptors and causes hyperalgesia in pain conditions. PRL enhances nociceptive responses by rapidly modulating channels in nociceptors. The molecular mechanisms underlying PRL-induced transient signaling in neurons are not well understood. Here we use a variety of cell biology and pharmacological approaches to show that PRL transiently enhanced capsaicin-evoked responses involve protein kinase C ϵ (PKCϵ) or phosphatidylinositol 3-kinase (PI3K) pathways in female rat trigeminal (TG) neurons. We next reconstituted PRL-induced signaling in a heterologous expression system and TG neurons from PRL receptor (PRLR)-null mutant mice by expressing rat PRLR-long isoform (PRLR-L), PRLR-short isoform (PRLR-S), or a mix of both. Results show that PRLR-S, but not PRLR-L, is capable of mediating PRL-induced transient enhancement of capsaicin responses in both male and female TG neurons. However, co-expression of PRLR-L with PRLR-S (1:1 ratio) leads to the inhibition of the transient PRL actions. Co-expression of PRLR-L deletion mutants with PRLR-S indicated that the cytoplasmic site adjacent to the trans-membrane domain of PRLR-L was responsible for inhibitory effects of PRLR-L. Furthermore, in situ hybridization and immunohistochemistry data indicate that in normal conditions, PRLR-L is expressed mainly in glia with little expression in rat sensory neurons (3–5%) and human nerves. The predominant PRLR form in TG neurons/nerves from rats and humans is PRLR-S. Altogether, PRL-induced transient signaling in sensory neurons is governed by PI3K or PKCϵ, mediated via the PRLR-S isoform, and transient effects mediated by PRLR-S are inhibited by presence of PRLR-L in these cells. PMID:24142695
Belugin, Sergei; Diogenes, Anibal R; Patil, Mayur J; Ginsburg, Erika; Henry, Michael A; Akopian, Armen N
2013-11-29
Prolactin (PRL) regulates activity of nociceptors and causes hyperalgesia in pain conditions. PRL enhances nociceptive responses by rapidly modulating channels in nociceptors. The molecular mechanisms underlying PRL-induced transient signaling in neurons are not well understood. Here we use a variety of cell biology and pharmacological approaches to show that PRL transiently enhanced capsaicin-evoked responses involve protein kinase C ε (PKCε) or phosphatidylinositol 3-kinase (PI3K) pathways in female rat trigeminal (TG) neurons. We next reconstituted PRL-induced signaling in a heterologous expression system and TG neurons from PRL receptor (PRLR)-null mutant mice by expressing rat PRLR-long isoform (PRLR-L), PRLR-short isoform (PRLR-S), or a mix of both. Results show that PRLR-S, but not PRLR-L, is capable of mediating PRL-induced transient enhancement of capsaicin responses in both male and female TG neurons. However, co-expression of PRLR-L with PRLR-S (1:1 ratio) leads to the inhibition of the transient PRL actions. Co-expression of PRLR-L deletion mutants with PRLR-S indicated that the cytoplasmic site adjacent to the trans-membrane domain of PRLR-L was responsible for inhibitory effects of PRLR-L. Furthermore, in situ hybridization and immunohistochemistry data indicate that in normal conditions, PRLR-L is expressed mainly in glia with little expression in rat sensory neurons (3-5%) and human nerves. The predominant PRLR form in TG neurons/nerves from rats and humans is PRLR-S. Altogether, PRL-induced transient signaling in sensory neurons is governed by PI3K or PKCε, mediated via the PRLR-S isoform, and transient effects mediated by PRLR-S are inhibited by presence of PRLR-L in these cells.
NASA Astrophysics Data System (ADS)
Li, Yi-Chao; Cui, Wan-Xing; Wang, Xu-Jing; Amthor, Franklin; Yao, Xin-Cheng
2011-03-01
Intrinsic optical signal (IOS) imaging has been established for noninvasive monitoring of stimulus-evoked physiological responses in the retina and other neural tissues. Recently, we extended the IOS imaging technology for functional evaluation of insulin secreting INS-1 cells. INS-1 cells provide a popular model for investigating β-cell dysfunction and diabetes. Our experiments indicate that IOS imaging allows simultaneous monitoring of glucose-stimulated physiological responses in multiple cells with high spatial (sub-cellular) and temporal (sub-second) resolution. Rapid image sequences reveal transient optical responses that have time courses comparable to glucose-evoked β-cell electrical activities.
Transient hazard model using radar data for predicting debris flows in Madison County, Virginia
Morrissey, M.M.; Wieczorek, G.F.; Morgan, B.A.
2004-01-01
During the rainstorm of June 27, 1995, roughly 330-750 mm of rain fell within a 16-hour period, initiating floods and over 600 debris flows in a small area (130 km2) of Madison County, VA. We developed a distributed version of Iverson's transient response model for regional slope stability analysis for the Madison County debris flows. This version of the model evaluates pore-pressure head response and factor of safety on a regional scale in areas prone to rainfall-induced shallow (<2-3 m) landslides. These calculations used soil properties of shear strength and hydraulic conductivity from laboratory measurements of soil samples collected from field sites where debris flows initiated. Rainfall data collected by radar every 6 minutes provided a basis for calculating the temporal variation of slope stability during the storm. The results demonstrate that the spatial and temporal variation of the factor of safety correlates with the movement of the storm cell. When the rainstorm was treated as two separate rainfall events and a larger hydraulic conductivity and friction angle than the laboratory values were used, the timing and location of landslides predicted by the model were in closer agreement with eyewitness observations of debris flows. Application of spatially variable initial pre-storm water table depth and soil properties may improve both the spatial and temporal prediction of instability.
Modeling hypertrophic IP3 transients in the cardiac myocyte.
Cooling, Michael; Hunter, Peter; Crampin, Edmund J
2007-11-15
Cardiac hypertrophy is a known risk factor for heart disease, and at the cellular level is caused by a complex interaction of signal transduction pathways. The IP3-calcineurin pathway plays an important role in stimulating the transcription factor NFAT which binds to DNA cooperatively with other hypertrophic transcription factors. Using available kinetic data, we construct a mathematical model of the IP3 signal production system after stimulation by a hypertrophic alpha-adrenergic agonist (endothelin-1) in the mouse atrial cardiac myocyte. We use a global sensitivity analysis to identify key controlling parameters with respect to the resultant IP3 transient, including the phosphorylation of cell-membrane receptors, the ligand strength and binding kinetics to precoupled (with G(alpha)GDP) receptor, and the kinetics associated with precoupling the receptors. We show that the kinetics associated with the receptor system contribute to the behavior of the system to a great extent, with precoupled receptors driving the response to extracellular ligand. Finally, by reparameterizing for a second hypertrophic alpha-adrenergic agonist, angiotensin-II, we show that differences in key receptor kinetic and membrane density parameters are sufficient to explain different observed IP3 transients in essentially the same pathway.
On the origin of reproducible sequential activity in neural circuits
NASA Astrophysics Data System (ADS)
Afraimovich, V. S.; Zhigulin, V. P.; Rabinovich, M. I.
2004-12-01
Robustness and reproducibility of sequential spatio-temporal responses is an essential feature of many neural circuits in sensory and motor systems of animals. The most common mathematical images of dynamical regimes in neural systems are fixed points, limit cycles, chaotic attractors, and continuous attractors (attractive manifolds of neutrally stable fixed points). These are not suitable for the description of reproducible transient sequential neural dynamics. In this paper we present the concept of a stable heteroclinic sequence (SHS), which is not an attractor. SHS opens the way for understanding and modeling of transient sequential activity in neural circuits. We show that this new mathematical object can be used to describe robust and reproducible sequential neural dynamics. Using the framework of a generalized high-dimensional Lotka-Volterra model, that describes the dynamics of firing rates in an inhibitory network, we present analytical results on the existence of the SHS in the phase space of the network. With the help of numerical simulations we confirm its robustness in presence of noise in spite of the transient nature of the corresponding trajectories. Finally, by referring to several recent neurobiological experiments, we discuss possible applications of this new concept to several problems in neuroscience.
On the origin of reproducible sequential activity in neural circuits.
Afraimovich, V S; Zhigulin, V P; Rabinovich, M I
2004-12-01
Robustness and reproducibility of sequential spatio-temporal responses is an essential feature of many neural circuits in sensory and motor systems of animals. The most common mathematical images of dynamical regimes in neural systems are fixed points, limit cycles, chaotic attractors, and continuous attractors (attractive manifolds of neutrally stable fixed points). These are not suitable for the description of reproducible transient sequential neural dynamics. In this paper we present the concept of a stable heteroclinic sequence (SHS), which is not an attractor. SHS opens the way for understanding and modeling of transient sequential activity in neural circuits. We show that this new mathematical object can be used to describe robust and reproducible sequential neural dynamics. Using the framework of a generalized high-dimensional Lotka-Volterra model, that describes the dynamics of firing rates in an inhibitory network, we present analytical results on the existence of the SHS in the phase space of the network. With the help of numerical simulations we confirm its robustness in presence of noise in spite of the transient nature of the corresponding trajectories. Finally, by referring to several recent neurobiological experiments, we discuss possible applications of this new concept to several problems in neuroscience.
Highlights of Transient Plume Impingement Model Validation and Applications
NASA Technical Reports Server (NTRS)
Woronowicz, Michael
2011-01-01
This paper describes highlights of an ongoing validation effort conducted to assess the viability of applying a set of analytic point source transient free molecule equations to model behavior ranging from molecular effusion to rocket plumes. The validation effort includes encouraging comparisons to both steady and transient studies involving experimental data and direct simulation Monte Carlo results. Finally, this model is applied to describe features of two exotic transient scenarios involving NASA Goddard Space Flight Center satellite programs.
Equivalent reduced model technique development for nonlinear system dynamic response
NASA Astrophysics Data System (ADS)
Thibault, Louis; Avitabile, Peter; Foley, Jason; Wolfson, Janet
2013-04-01
The dynamic response of structural systems commonly involves nonlinear effects. Often times, structural systems are made up of several components, whose individual behavior is essentially linear compared to the total assembled system. However, the assembly of linear components using highly nonlinear connection elements or contact regions causes the entire system to become nonlinear. Conventional transient nonlinear integration of the equations of motion can be extremely computationally intensive, especially when the finite element models describing the components are very large and detailed. In this work, the equivalent reduced model technique (ERMT) is developed to address complicated nonlinear contact problems. ERMT utilizes a highly accurate model reduction scheme, the System equivalent reduction expansion process (SEREP). Extremely reduced order models that provide dynamic characteristics of linear components, which are interconnected with highly nonlinear connection elements, are formulated with SEREP for the dynamic response evaluation using direct integration techniques. The full-space solution will be compared to the response obtained using drastically reduced models to make evident the usefulness of the technique for a variety of analytical cases.
Sensitivity of Antarctic sea ice to the Southern Annular Mode in coupled climate models
NASA Astrophysics Data System (ADS)
Holland, Marika M.; Landrum, Laura; Kostov, Yavor; Marshall, John
2017-09-01
We assess the sea ice response to Southern Annular Mode (SAM) anomalies for pre-industrial control simulations from the Coupled Model Intercomparison Project (CMIP5). Consistent with work by Ferreira et al. (J Clim 28:1206-1226, 2015. doi: 10.1175/JCLI-D-14-00313.1), the models generally simulate a two-timescale response to positive SAM anomalies, with an initial increase in ice followed by an eventual sea ice decline. However, the models differ in the cross-over time at which the change in ice response occurs, in the overall magnitude of the response, and in the spatial distribution of the response. Late twentieth century Antarctic sea ice trends in CMIP5 simulations are related in part to different modeled responses to SAM variability acting on different time-varying transient SAM conditions. This explains a significant fraction of the spread in simulated late twentieth century southern hemisphere sea ice extent trends across the model simulations. Applying the modeled sea ice response to SAM variability but driven by the observed record of SAM suggests that variations in the austral summer SAM, which has exhibited a significant positive trend, have driven a modest sea ice decrease. However, additional work is needed to narrow the considerable model uncertainty in the climate response to SAM variability and its implications for 20th-21st century trends.
Fuel-injection control of S.I. engines
DOE Office of Scientific and Technical Information (OSTI.GOV)
Choi, S.B.; Won, M.; Hedrick, J.K.
1994-12-31
It is known that about 50% of air pollutants comes from automotive engine exhaust, and mostly in a transient state operation. However, the wide operating range, the inherent nonlinearities of the induction process and the large modeling uncertainties make the design of the fuel-injection controller very difficult. Also, the unavoidable large time-delay between control action and measurement causes the problem of chattering. In this paper, an observer-based control algorithm based on sliding mode control technique is suggested for fast response and small amplitude chattering of the air-to-fuel ratio. A direct adaptive control using Gaussian networks is applied to the compensationmore » of transient fueling dynamics. The proposed controller is simple enough for on-line computation and is implemented on an automotive engine using a PC-386. The simulation and the experimental results show that this algorithm reduces the chattering magnitude considerably and is robust to modeling errors.« less
Baruch, Kuti; Rosenzweig, Neta; Kertser, Alexander; Deczkowska, Aleksandra; Sharif, Alaa Mohammad; Spinrad, Amit; Tsitsou-Kampeli, Afroditi; Sarel, Ayelet; Cahalon, Liora; Schwartz, Michal
2015-01-01
Alzheimer's disease (AD) is a neurodegenerative disorder in which chronic neuroinflammation contributes to disease escalation. Nevertheless, while immunosuppressive drugs have repeatedly failed in treating this disease, recruitment of myeloid cells to the CNS was shown to play a reparative role in animal models. Here we show, using the 5XFAD AD mouse model, that transient depletion of Foxp3+ regulatory T cells (Tregs), or pharmacological inhibition of their activity, is followed by amyloid-β plaque clearance, mitigation of the neuroinflammatory response and reversal of cognitive decline. We further show that transient Treg depletion affects the brain's choroid plexus, a selective gateway for immune cell trafficking to the CNS, and is associated with subsequent recruitment of immunoregulatory cells, including monocyte-derived macrophages and Tregs, to cerebral sites of plaque pathology. Our findings suggest targeting Treg-mediated systemic immunosuppression for treating AD. PMID:26284939
Arctic-North Pacific Coupled Impacts on the Late Autumn Cold in North America
NASA Technical Reports Server (NTRS)
Sung, Mi-Kyung; Kim, Baek-Min; Baik, Eun-Hyuk; Lim, Young-Kwon; Kim, Seong-Joong
2016-01-01
The Pacific Decadal Oscillation (PDO) is known to bring an anomalously cold (warm) period to southeastern (northwestern) North America during the cold season of its positive phase through a Rossby wave linkage. This study provides evidence that the remote connection between the North Pacific and the downstream temperature over central North America is strengthened by the warm arctic conditions over the Chukchi and East Siberian Sea, especially in the late autumn season. The modulation effect of the Arctic manifests itself as an altered Rossby wave response to a transient vorticity forcing that results from an equatorward storm track shift, which is induced collaboratively by the PDO and the warm Arctic. This observational finding is supported by two independent modeling experiments: 1) an idealized coupled GCM experiment being nudged toward the warm arctic surface condition and 2) a simple stationary wave model (SWM) experiment forced by transient eddy forcing.
Sakashita, Y.; Kanai, M.; Sugimoto, T.; Taki, S.; Takamori, M.
1997-01-01
OBJECTIVE—Previous reports about changes in cerebral blood flow (CBF) in transient global amnesia disclosed decreased flow in some parts of the brain. However, CBF analyses in most reports were qualitative but not quantitative. The purpose of this study was to determine changes in CBF in transient global amnesia. METHODS—The CBF was measured and the vasoreactive response to acetazolamide was evaluated in six patients with transient global amnesia using technetium-99m hexamethylpropylene amine oxime single-photon emission computed tomography (SPECT). The CBF was measured during an attack in two patients and soon after an attack in the other four. About one month later, CBF was re-evaluated in each patient. RESULTS—Two patients examined during an attack and one patient examined five hours after an attack had increased blood flow in the occipital cortex and cerebellum. Three patients examined at six to 10 hours after an attack had decreased blood flow in the thalamus, cerebellum, or putamen. These abnormalities of blood flow almost disappeared in all patients one month after onset. The vasodilatory response to acetazolamide, which was evaluated initially using SPECT, was poor in areas of increased blood flow. By the second evaluation of CBF with acetazolamide, the vasodilatory response had returned to normal. CONCLUSIONS—In a patient with transient global amnesia, CBF increased in the vertebrobasilar territory during the attack and decreased afterwards. The vasodilatory response to acetazolamide may be impaired in the parts of the brain with increased blood flow. It is suggested that transient global amnesia is distinct from migraine but may share the same underlying mechanism. PMID:9408101
Integrated Turbine-Based Combined Cycle Dynamic Simulation Model
NASA Technical Reports Server (NTRS)
Haid, Daniel A.; Gamble, Eric J.
2011-01-01
A Turbine-Based Combined Cycle (TBCC) dynamic simulation model has been developed to demonstrate all modes of operation, including mode transition, for a turbine-based combined cycle propulsion system. The High Mach Transient Engine Cycle Code (HiTECC) is a highly integrated tool comprised of modules for modeling each of the TBCC systems whose interactions and controllability affect the TBCC propulsion system thrust and operability during its modes of operation. By structuring the simulation modeling tools around the major TBCC functional modes of operation (Dry Turbojet, Afterburning Turbojet, Transition, and Dual Mode Scramjet) the TBCC mode transition and all necessary intermediate events over its entire mission may be developed, modeled, and validated. The reported work details the use of the completed model to simulate a TBCC propulsion system as it accelerates from Mach 2.5, through mode transition, to Mach 7. The completion of this model and its subsequent use to simulate TBCC mode transition significantly extends the state-of-the-art for all TBCC modes of operation by providing a numerical simulation of the systems, interactions, and transient responses affecting the ability of the propulsion system to transition from turbine-based to ramjet/scramjet-based propulsion while maintaining constant thrust.
NASA Astrophysics Data System (ADS)
Villar, V. Ashley; Berger, Edo; Metzger, Brian D.; Guillochon, James
2017-11-01
The duration-luminosity phase space (DLPS) of optical transients is used, mostly heuristically, to compare various classes of transient events, to explore the origin of new transients, and to influence optical survey observing strategies. For example, several observational searches have been guided by intriguing voids and gaps in this phase space. However, we should ask, do we expect to find transients in these voids given our understanding of the various heating sources operating in astrophysical transients? In this work, we explore a broad range of theoretical models and empirical relations to generate optical light curves and to populate the DLPS. We explore transients powered by adiabatic expansion, radioactive decay, magnetar spin-down, and circumstellar interaction. For each heating source, we provide a concise summary of the basic physical processes, a physically motivated choice of model parameter ranges, an overall summary of the resulting light curves and their occupied range in the DLPS, and how the various model input parameters affect the light curves. We specifically explore the key voids discussed in the literature: the intermediate-luminosity gap between classical novae and supernovae, and short-duration transients (≲ 10 days). We find that few physical models lead to transients that occupy these voids. Moreover, we find that only relativistic expansion can produce fast and luminous transients, while for all other heating sources events with durations ≲ 10 days are dim ({M}{{R}}≳ -15 mag). Finally, we explore the detection potential of optical surveys (e.g., Large Synoptic Survey Telescope) in the DLPS and quantify the notion that short-duration and dim transients are exponentially more difficult to discover in untargeted surveys.
The Rapid Gamma-ray Burst Response Campaign with ROTSE
NASA Astrophysics Data System (ADS)
Balsano, R.; Bloch, J.; Casperson, D.; Fletcher, S.; Gisler, G.; Hills, J.; Priedhorsky, W.; Szymanski, J.; Wren, J.; Akerlof, C.; Kehoe, R.; McKay, T.; Pawl, A.; Marshall, S.; Lee, B.; Barthelmy, S.; Butterworth, P.; Cline, T.
2000-04-01
The main goal of the Robotic Optical Transient Search Experiment (ROTSE) is to detect optical emission from Gamma-ray Bursts (GRBs) during and immediately following GRBs. The instruments comprising ROTSE consist of wide-field optics on rapidly slewing mounts optimized for quick response to GRBs localized to several degree regions. Thus far, only one prompt optical counterpart to a GRB has been discovered although simple scaling arguments suggest more should be easily detected. This talk will cover ROTSE responses to GRBs detected by the Burst and Transient Source Experiment and the soon-to-be-launched High Energy Transient Experiment. The expansion of ROTSE to a global network of identical telescopes will also be briefly discussed.
Circuit transients due to negative bias arcs-II. [on solar cell power systems in low earth orbit
NASA Technical Reports Server (NTRS)
Metz, R. N.
1986-01-01
Two new models of negative-bias arcing on a solar cell power system in Low Earth Orbit are presented. One is an extended, analytical model and the other is a non-linear, numerical model. The models are based on an earlier analytical model in which the interactions between solar cell interconnects and the space plasma as well as the parameters of the power circuit are approximated linearly. Transient voltages due to arcs struck at the negative thermal of the solar panel are calculated in the time domain. The new models treat, respectively, further linear effects within the solar panel load circuit and non-linear effects associated with the plasma interactions. Results of computer calculations with the models show common-mode voltage transients of the electrically floating solar panel struck by an arc comparable to the early model but load transients that differ substantially from the early model. In particular, load transients of the non-linear model can be more than twice as great as those of the early model and more than twenty times as great as the extended, linear model.
Reversal learning and resurgence of operant behavior in zebrafish (Danio rerio).
Kuroda, Toshikazu; Mizutani, Yuto; Cançado, Carlos R X; Podlesnik, Christopher A
2017-09-01
Zebrafish are used extensively as vertebrate animal models in biomedical research for having such features as a fully sequenced genome and transparent embryo. Yet, operant-conditioning studies with this species are scarce. The present study investigated reversal learning and resurgence of operant behavior in zebrafish. A target response (approaching a sensor) was reinforced in Phase 1. In Phase 2, the target response was extinguished while reinforcing an alternative response (approaching a different sensor). In Phase 3, extinction was in effect for the target and alternative responses. Reversal learning was demonstrated when responding tracked contingency changes between Phases 1 and 2. Moreover, resurgence occurred in 10 of 13 fish in Phase 3: Target response rates increased transiently and exceeded rates of an unreinforced control response. The present study provides the first evidence with zebrafish supporting reversal learning between discrete operant responses and a laboratory model of relapse. These findings open the possibility to assessing genetic influences of operant behavior generally and in models of relapse (e.g., resurgence, renewal, reinstatement). Copyright © 2017 Elsevier B.V. All rights reserved.
Climate system properties determining the social cost of carbon
NASA Astrophysics Data System (ADS)
Otto, Alexander; Todd, Benjamin J.; Bowerman, Niel; Frame, David J.; Allen, Myles R.
2013-06-01
The choice of an appropriate scientific target to guide global mitigation efforts is complicated by uncertainties in the temperature response to greenhouse gas emissions. Much climate policy discourse has been based on the equilibrium global mean temperature increase following a concentration stabilization scenario. This is determined by the equilibrium climate sensitivity (ECS) which, in many studies, shows persistent, fat-tailed uncertainty. However, for many purposes, the equilibrium response is less relevant than the transient response. Here, we show that one prominent policy variable, the social cost of carbon (SCC), is generally better constrained by the transient climate response (TCR) than by the ECS. Simple analytic expressions show the SCC to be directly proportional to the TCR under idealized assumptions when the rate at which we discount future damage equals 2.8%. Using ensemble simulations of a simple climate model we find that knowing the true value of the TCR can reduce the relative uncertainty in the SCC substantially more, up to a factor of 3, than knowing the ECS under typical discounting assumptions. We conclude that the TCR, which is better constrained by observations, less subject to fat-tailed uncertainty and more directly related to the SCC, is generally preferable to the ECS as a single proxy for the climate response in SCC calculations.
NASA Astrophysics Data System (ADS)
Yanites, Brian J.; Becker, Jens K.; Madritsch, Herfried; Schnellmann, Michael; Ehlers, Todd A.
2017-11-01
Landscape evolution is a product of the forces that drive geomorphic processes (e.g., tectonics and climate) and the resistance to those processes. The underlying lithology and structural setting in many landscapes set the resistance to erosion. This study uses a modified version of the Channel-Hillslope Integrated Landscape Development (CHILD) landscape evolution model to determine the effect of a spatially and temporally changing erodibility in a terrain with a complex base level history. Specifically, our focus is to quantify how the effects of variable lithology influence transient base level signals. We set up a series of numerical landscape evolution models with increasing levels of complexity based on the lithologic variability and base level history of the Jura Mountains of northern Switzerland. The models are consistent with lithology (and therewith erodibility) playing an important role in the transient evolution of the landscape. The results show that the erosion rate history at a location depends on the rock uplift and base level history, the range of erodibilities of the different lithologies, and the history of the surface geology downstream from the analyzed location. Near the model boundary, the history of erosion is dominated by the base level history. The transient wave of incision, however, is quite variable in the different model runs and depends on the geometric structure of lithology used. It is thus important to constrain the spatiotemporal erodibility patterns downstream of any given point of interest to understand the evolution of a landscape subject to variable base level in a quantitative framework.
Modeling of Nonlinear Optical Response in Gaseous Media and Its Comparison with Experiment
NASA Astrophysics Data System (ADS)
Xia, Yi
This thesis demonstrates the model and application of nonlinear optical response with Metastable Electronic State Approach (MESA) in ultrashort laser propagation and verifies accuracy of MESA through extensive comparison with experimental data. The MESA is developed from quantum mechanics to describe the nonlinear off-resonant optical response together with strong-field ionization in gaseous medium. The conventional light-matter interaction models are based on a piece-wise approach where Kerr effect and multi-photon ionization are treated as independent nonlinear responses. In contrast, MESA is self-consistent as the response from freed electrons and bound electrons are microscopically linked. It also can be easily coupled to the Unidirectional Pulse Propagation Equations (UPPE) for large scale simulation of experiments. This work tests the implementation of MESA model in simulation of nonlinear phase transients of ultrashort pulse propagation in a gaseous medium. The phase transient has been measured through Single-Shot Supercontinuum Spectral Interferometry. This technique can achieve high temporal resolution (10 fs) and spatial resolution (5 mum). Our comparison between simulation and experiment gives a quantitive test of MESA model including post-adiabatic corrections. This is the first time such a comparison was achieved for a theory suitable for large scale numerical simulation of modern nonlinear-optics experiments. In more than one respect, ours is a first-of-a-kind achievement. In particular, • Large amount of data are compared. We compare the data of nonlinear response induced by different pump intensity in Ar and Nitrogen. The data sets are three dimensions including two transverse spacial dimensions and one axial temporal dimension which reflect the whole structure of nonlinear response including the interplay between Kerr and plasma-induced effects. The resolutions of spatial and temporal dimension are about a few micrometer and several femtosecond. • The regime of light-matter interaction investigated here is between the strong and perturbative, where the pulse intensity can induce nonlinear refractive index change and partial ionization of dielectric medium. Obviously, such regimes are difficult to study both experimentally and theoretically. • MESA is a quantum based model, but it retains the same computation complexity as conventional light-matter interaction model. MESA contains the response from both bound and continuum states in a single self-consistent "Package". So, it is fair to say that this experiment-theory comparison sets a new standard for nonlinear light-matter interaction models and their verification in the area of extreme nonlinear optics.
NASA Astrophysics Data System (ADS)
Kreider, Kenneth G.; DeWitt, David P.; Fowler, Joel B.; Proctor, James E.; Kimes, William A.; Ripple, Dean C.; Tsai, Benjamin K.
2004-04-01
Recent studies on dynamic temperature profiling and lithographic performance modeling of the post-exposure bake (PEB) process have demonstrated that the rate of heating and cooling may have an important influence on resist lithographic response. Measuring the transient surface temperature during the heating or cooling process with such accuracy can only be assured if the sensors embedded in or attached to the test wafer do not affect the temperature distribution in the bare wafer. In this paper we report on an experimental and analytical study to compare the transient response of embedded platinum resistance thermometer (PRT) sensors with surface-deposited, thin-film thermocouples (TFTC). The TFTCs on silicon wafers have been developed at NIST to measure wafer temperatures in other semiconductor thermal processes. Experiments are performed on a test bed built from a commercial, fab-qualified module with hot and chill plates using wafers that have been instrumented with calibrated type-E (NiCr/CuNi) TFTCs and commercial PRTs. Time constants were determined from an energy-balance analysis fitting the temperature-time derivative to the wafer temperature during the heating and cooling processes. The time constants for instrumented wafers ranged from 4.6 s to 5.1 s on heating for both the TFTC and PRT sensors, with an average difference less than 0.1 s between the TFTCs and PRTs and slightly greater differences on cooling.
Student Learning in an Electric Circuit Theory Course: Critical Aspects and Task Design
ERIC Educational Resources Information Center
Carstensen, Anna-Karin; Bernhard, Jonte
2009-01-01
Understanding time-dependent responses, such as transients, is important in electric circuit theory and other branches of engineering. However, transient response is considered difficult to learn since familiarity with advanced mathematical tools such as Laplace transforms is required. Here, we analyse and describe a novel learning environment…
Central circulatory hemodynamics as a function of gravitational stress
NASA Technical Reports Server (NTRS)
Latham, Rick D.; White, C. D.; Fanton, J. W.; Owens, R. W.; Barber, J. F.; Lewkowski, B. E.; Goff, O. T.
1991-01-01
This study focuses on an evaluation of the central hemodynamics in a nonhuman primate model to variations in gravitational states. The baboon, phylogenectically close to man, was chosen as the human surrogate. The study environments selected are head-down and head-up tilt in the physiology laboratory, centrifugation to test hypergravic stress, and parabolic flights to test transient acute responses to microgravity.
Input filter compensation for switching regulators
NASA Technical Reports Server (NTRS)
Lee, F. C.
1984-01-01
Problems caused by input filter interaction and conventional input filter design techniques are discussed. The concept of feedforward control is modeled with an input filter and a buck regulator. Experimental measurement and comparison to the analytical predictions is carried out. Transient response and the use of a feedforward loop to stabilize the regulator system is described. Other possible applications for feedforward control are included.
H∞ control of combustion in diesel engines using a discrete dynamics model
NASA Astrophysics Data System (ADS)
Hirata, Mitsuo; Ishizuki, Sota; Suzuki, Masayasu
2016-09-01
This paper proposes a control method for combustion in diesel engines using a discrete dynamics model. The proposed two-degree-of-freedom control scheme achieves not only good feedback properties such as disturbance suppression and robust stability but also a good transient response. The method includes a feedforward controller constructed from the inverse model of the plant, and a feedback controller designed by an Hcontrol method, which reduces the effect of the turbocharger lag. The effectiveness of the proposed method is evaluated via numerical simulations.
NASA Technical Reports Server (NTRS)
1974-01-01
The transient and steady state response of the respiratory control system for variations in volumetric fractions of inspired gases and special system parameters are modeled. The program contains the capability to change workload. The program is based on Grodins' respiratory control model and can be envisioned as a feedback control system comprised of a plant (the controlled system) and the regulating component (controlling system). The controlled system is partitioned into 3 compartments corresponding to lungs, brain, and tissue with a fluid interconnecting patch representing the blood.
Time-resolved spectroscopy at surfaces and adsorbate dynamics:insights from a model-system approach
NASA Astrophysics Data System (ADS)
Boström, Emil; Mikkelsen, Anders; Verdozzi, Claudio
We introduce a finite-system, model description of the initial stages of femtosecond laser induced desorption at surfaces. Using the exact many-body time evolution and also results from a novel time-dependent DFT description for electron-nuclear systems, we analyse the competition between several surface-response mechanisms and electronic correlations in the transient and longer time dynamics under the influence of dipole-coupled fields. Our model allows us to explore how coherent multiple-pulse protocols impact desorption in a variety of prototypical experiments.
NASA Astrophysics Data System (ADS)
Alamri, Sagr; Li, Bing; Tan, K. T.
2018-03-01
Dissipative elastic metamaterials have attracted increased attention in recent times. This paper presents the development of a dissipative elastic metamaterial with multiple Maxwell-type resonators for stress wave attenuation. The mechanism of the dissipation effect on the vibration characteristics is systematically investigated by mass-spring-damper models with single and dual resonators. Based on the parameter optimization, it is revealed that a broadband wave attenuation region (stopping band) can be obtained by properly utilizing interactions from resonant motions and viscoelastic effects of the Maxwell-type oscillators. The relevant numerical verifications are conducted for various cases, and excellent agreement between the numerical and theoretical frequency response functions is shown. The design of this dissipative metamaterial system is further applied for dynamic load mitigation and blast wave attenuation. Moreover, the transient response in the continuum model is designed and analyzed for more robust design. By virtue of the bandgap merging effect induced by the Maxwell-type damper, the transient blast wave can be almost completely suppressed in the low frequency range. A significantly improved performance of the proposed dissipative metamaterials for stress wave mitigation is verified in both time and frequency domains.
Transient Approximation of SAFE-100 Heat Pipe Operation
NASA Technical Reports Server (NTRS)
Bragg-Sitton, Shannon M.; Reid, Robert S.
2005-01-01
Engineers at Los Alamos National Laboratory (LANL) have designed several heat pipe cooled reactor concepts, ranging in power from 15 kWt to 800 kWt, for both surface power systems and nuclear electric propulsion systems. The Safe, Affordable Fission Engine (SAFE) is now being developed in a collaborative effort between LANL and NASA Marshall Space Flight Center (NASA/MSFC). NASA is responsible for fabrication and testing of non-nuclear, electrically heated modules in the Early Flight Fission Test Facility (EFF-TF) at MSFC. In-core heat pipes must be properly thawed as the reactor power starts. Computational models have been developed to assess the expected operation of a specific heat pipe design during start-up, steady state operation, and shutdown. While computationally intensive codes provide complete, detailed analyses of heat pipe thaw, a relatively simple. concise routine can also be applied to approximate the response of a heat pipe to changes in the evaporator heat transfer rate during start-up and power transients (e.g., modification of reactor power level) with reasonably accurate results. This paper describes a simplified model of heat pipe start-up that extends previous work and compares the results to experimental measurements for a SAFE-100 type heat pipe design.
INITIAL ANALYSIS OF TRANSIENT POWER TIME LAG DUE TO HETEROGENEITY WITHIN THE TREAT FUEL MATRIX.
DOE Office of Scientific and Technical Information (OSTI.GOV)
D.M. Wachs; A.X. Zabriskie, W.R. Marcum
2014-06-01
The topic Nuclear Safety encompasses a broad spectrum of focal areas within the nuclear industry; one specific aspect centers on the performance and integrity of nuclear fuel during a reactivity insertion accident (RIA). This specific accident has proven to be fundamentally difficult to theoretically characterize due to the numerous empirically driven characteristics that quantify the fuel and reactor performance. The Transient Reactor Test (TREAT) facility was designed and operated to better understand fuel behavior under extreme (i.e. accident) conditions; it was shutdown in 1994. Recently, efforts have been underway to commission the TREAT facility to continue testing of advanced accidentmore » tolerant fuels (i.e. recently developed fuel concepts). To aid in the restart effort, new simulation tools are being used to investigate the behavior of nuclear fuels during facility’s transient events. This study focuses specifically on the characterizing modeled effects of fuel particles within the fuel matrix of the TREAT. The objective of this study was to (1) identify the impact of modeled heterogeneity within the fuel matrix during a transient event, and (2) demonstrate acceptable modeling processes for the purpose of TREAT safety analyses, specific to fuel matrix and particle size. Hypothetically, a fuel that is dominantly heterogeneous will demonstrate a clearly different temporal heating response to that of a modeled homogeneous fuel. This time difference is a result of the uniqueness of the thermal diffusivity within the fuel particle and fuel matrix. Using MOOSE/BISON to simulate the temperature time-lag effect of fuel particle diameter during a transient event, a comparison of the average graphite moderator temperature surrounding a spherical particle of fuel was made for both types of fuel simulations. This comparison showed that at a given time and with a specific fuel particle diameter, the fuel particle (heterogeneous) simulation and the homogeneous simulation were related by a multiplier relative to the average moderator temperature. As time increases the multiplier is comparable to the factor found in a previous analytical study from literature. The implementation of this multiplier and the method of analysis may be employed to remove assumptions and increase fidelity for future research on the effect of fuel particles during transient events.« less
Kontis, Angelo L.
1999-01-01
The seaward limit of the fresh ground-water system underlying Kings and Queens Counties on Long Island, N.Y., is at the freshwater-saltwater transition zone. This zone has been conceptualized in transient-state, three-dimensional models of the aquifer system as a sharp interface between freshwater and saltwater, and represented as a stationary, zero lateral-flow boundary. In this study, a pair of two-dimensional, four-layer ground-water flow models representing a generalized vertical section in Kings County and one in adjacent Queens County were developed to evaluate the validity of the boundary condition used in three-dimensional models of the aquifer system. The two-dimensional simulations used a model code that can simulate the movement of a sharp interface in response to transient stress. Sensitivity of interface movement to four factors was analyzed; these were (1) the method of simulating vertical leakage between freshwater and saltwater; (2) recharge at the normal rate, at 50-percent of the normal rate, and at zero for a prolonged (3-year) period; (3) high, medium, and low pumping rates; and (4) pumping from a hypothetical cluster of wells at two locations. Results indicate that the response of the interfaces to the magnitude and duration of pumping and the location of the hypothetical wells is probably sufficiently slow that the interfaces in three-dimensional models can reasonably be approximated as stationary, zero-lateral- flow boundaries.
NASA Astrophysics Data System (ADS)
Kramm, Gerhard
2010-07-01
In this paper we discuss the meaning of feedback parameter, greenhouse effect and transient climate response usually related to the globally averaged energy balance model of Schneider and Mass. After scrutinizing this model and the corresponding planetary radiation balance we state that (a) the this globally averaged energy balance model is flawed by unsuitable physical considerations, (b) the planetary radiation balance for an Earth in the absence of an atmosphere is fraught by the inappropriate assumption of a uniform surface temperature, the so-called radiative equilibrium temperature of about 255 K, and (c) the effect of the radiative anthropogenic forcing, considered as a perturbation to the natural system, is much smaller than the uncertainty involved in the solution of the model of Schneider and Mass. This uncertainty is mainly related to the empirical constants suggested by various authors and used for predicting the emission of infrared radiation by the Earth's skin. Furthermore, after inserting the absorption of solar radiation by atmospheric constituents and the exchange of sensible and latent heat between the Earth and the atmosphere into the model of Schneider and Mass the surface temperatures become appreciably lesser than the radiative equilibrium temperature. Moreover, neither the model of Schneider and Mass nor the Dines-type two-layer energy balance model for the Earth-atmosphere system, both contain the planetary radiation balance for an Earth in the absence of an atmosphere as an asymptotic solution, do not provide evidence for the existence of the so-called atmospheric greenhouse effect if realistic empirical data are used.
Red Blood Cell Passage of Small Capillaries Is Associated with Transient Ca2+-mediated Adaptations.
Danielczok, Jens G; Terriac, Emmanuel; Hertz, Laura; Petkova-Kirova, Polina; Lautenschläger, Franziska; Laschke, Matthias W; Kaestner, Lars
2017-01-01
When red blood cells (RBCs) pass constrictions or small capillaries they need to pass apertures falling well below their own cross section size. We used different means of mechanical stimulations (hypoosmotic swelling, local mechanical stimulation, passing through microfluidic constrictions) to observe cellular responses of human RBCs in terms of intracellular Ca 2+ -signaling by confocal microscopy of Fluo-4 loaded RBCs. We were able to confirm our in vitro results in a mouse dorsal skinfold chamber model showing a transiently increased intracellular Ca 2+ when RBCs were passing through small capillaries in vivo . Furthermore, we performed the above-mentioned in vitro experiments as well as measurements of RBCs filterability under various pharmacological manipulations (GsMTx-4, TRAM-34) to explore the molecular mechanism of the Ca 2+ -signaling. Based on these experiments we conclude that mechanical stimulation of RBCs activates mechano-sensitive channels most likely Piezo1. This channel activity allows Ca 2+ to enter the cell, leading to a transient activation of the Gardos-channel associated with K + , Cl - , and water loss, i.e., with a transient volume adaptation facilitating the passage of the RBCs through the constriction.
Red Blood Cell Passage of Small Capillaries Is Associated with Transient Ca2+-mediated Adaptations
Danielczok, Jens G.; Terriac, Emmanuel; Hertz, Laura; Petkova-Kirova, Polina; Lautenschläger, Franziska; Laschke, Matthias W.; Kaestner, Lars
2017-01-01
When red blood cells (RBCs) pass constrictions or small capillaries they need to pass apertures falling well below their own cross section size. We used different means of mechanical stimulations (hypoosmotic swelling, local mechanical stimulation, passing through microfluidic constrictions) to observe cellular responses of human RBCs in terms of intracellular Ca2+-signaling by confocal microscopy of Fluo-4 loaded RBCs. We were able to confirm our in vitro results in a mouse dorsal skinfold chamber model showing a transiently increased intracellular Ca2+ when RBCs were passing through small capillaries in vivo. Furthermore, we performed the above-mentioned in vitro experiments as well as measurements of RBCs filterability under various pharmacological manipulations (GsMTx-4, TRAM-34) to explore the molecular mechanism of the Ca2+-signaling. Based on these experiments we conclude that mechanical stimulation of RBCs activates mechano-sensitive channels most likely Piezo1. This channel activity allows Ca2+ to enter the cell, leading to a transient activation of the Gardos-channel associated with K+, Cl−, and water loss, i.e., with a transient volume adaptation facilitating the passage of the RBCs through the constriction. PMID:29259557
NASA Astrophysics Data System (ADS)
Ducci, L.; Sidoli, L.; Paizis, A.
2010-11-01
We performed a systematic analysis of all INTEGRAL observations from 2003 to 2009 of 14 supergiant fast X-ray transients (SFXTs), implying a net exposure time of about 30 Ms. For each source we obtained light curves and spectra (3-100 keV), discovering several new outbursts. We discuss the X-ray behaviour of SFXTs emerging from our analysis in the framework of the clumpy wind accretion mechanism we proposed. We discuss the effect of X-ray photoionization on accretion in close binary systems such as IGR J16479-4514 and IGR J17544-2619. We show that, because of X-ray photoionization, there is a high probability of an accretion disc forming from the capture of angular momentum in IGR J16479-4514, and we suggest that the formation of transient accretion discs could be partly responsible for the flaring activity in SFXTs with narrow orbits. We also propose an alternative way to explain the origin of flares with peculiar shapes observed in our analysis applying the model of Lamb et al., which is based on accretion via the Rayleigh-Taylor instability and was originally proposed to explain Type II bursts.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Vermeul, Vincent R.; Cole, Charles R.; Bergeron, Marcel P.
2001-08-29
The baseline three-dimensional transient inverse model for the estimation of site-wide scale flow parameters, including their uncertainties, using data on the transient behavior of the unconfined aquifer system over the entire historical period of Hanford operations, has been modified to account for the effects of basalt intercommunication between the Hanford unconfined aquifer and the underlying upper basalt confined aquifer. Both the baseline and alternative conceptual models (ACM-1) considered only the groundwater flow component and corresponding observational data in the 3-Dl transient inverse calibration efforts. Subsequent efforts will examine both groundwater flow and transport. Comparisons of goodness of fit measures andmore » parameter estimation results for the ACM-1 transient inverse calibrated model with those from previous site-wide groundwater modeling efforts illustrate that the new 3-D transient inverse model approach will strengthen the technical defensibility of the final model(s) and provide the ability to incorporate uncertainty in predictions related to both conceptual model and parameter uncertainty. These results, however, indicate that additional improvements are required to the conceptual model framework. An investigation was initiated at the end of this basalt inverse modeling effort to determine whether facies-based zonation would improve specific yield parameter estimation results (ACM-2). A description of the justification and methodology to develop this zonation is discussed.« less
NASA Technical Reports Server (NTRS)
Karimi, Amir
1990-01-01
METMAN is a 41-node transient metabolic computer code developed in 1970 and revised in 1989 by Lockheed Engineering and Sciences, Inc. This program relies on a mathematical model to predict the transient temperature distribution in a body influenced by metabolic heat generation and thermal interaction with the environment. A more complex 315-node model is also available that not only simulates the thermal response of a body exposed to a warm environment, but is also capable of describing the thermal response resulting from exposure to a cold environment. It is important to compare the two models for the prediction of the body's thermal response to metabolic heat generation and exposure to various environmental conditions. Discrepancies between the twi models may warrant an investigation of METMAN to ensure its validity for describing the body's thermal response in space environment. The Liquid Cooling and Ventilation Garment is a subsystem of the Extravehicular Mobility Unit (EMU). This garment, worn under the pressure suit, contains the liquid cooling tubing and gas ventilation manifolds; its purpose is to alleviate or reduce thermal stress resulting from metabolic heat generation. There is renewed interest in modifying this garment through identification of the locus of maximum heat transfer at body-liquid cooled tubing interface. The sublimator is a vital component of the Primary Life Support System (PLSS) in the EMU. It acts as a heat sink to remove heat and humidity from the gas ventilating circuit and the liquid cooling loop of the LCVG. The deficiency of the sublimator is that the ice, used as the heat sink, sublimates into space. There is an effort to minimize water losses in the feedwater circuit of the EMU. This requires developing new concepts to design an alternative heat sink system. Efforts are directed to review and verify the heat transfer formulation of the analytical model employed by METMAN. A conceptual investigation of regenerative non-venting heat-sink subsystem for the EMU is recommended.
NASA Astrophysics Data System (ADS)
Tang, J.; Riley, W. J.
2017-12-01
Most existing soil carbon cycle models have modeled the moisture and temperature dependence of soil respiration using deterministic response functions. However, empirical data suggest abundant variability in both of these dependencies. We here use the recently developed SUPECA (Synthesizing Unit and Equilibrium Chemistry Approximation) theory and a published dynamic energy budget based microbial model to investigate how soil carbon decomposition responds to changes in soil moisture and temperature under the influence of organo-mineral interactions. We found that both the temperature and moisture responses are hysteretic and cannot be represented by deterministic functions. We then evaluate how the multi-scale variability in temperature and moisture forcing affect soil carbon decomposition. Our results indicate that when the model is run in scenarios mimicking laboratory incubation experiments, the often-observed temperature and moisture response functions can be well reproduced. However, when such response functions are used for model extrapolation involving more transient variability in temperature and moisture forcing (as found in real ecosystems), the dynamic model that explicitly accounts for hysteresis in temperature and moisture dependency produces significantly different estimations of soil carbon decomposition, suggesting there are large biases in models that do not resolve such hysteresis. We call for more studies on organo-mineral interactions to improve modeling of such hysteresis.
Evaluating Zeolite-Modified Sensors: towards a faster set of chemical sensors
NASA Astrophysics Data System (ADS)
Berna, A. Z.; Vergara, A.; Trincavelli, M.; Huerta, R.; Afonja, A.; Parkin, I. P.; Binions, R.; Trowell, S.
2011-09-01
The responses of zeolite-modified sensors, prepared by screen printing layers of chromium titanium oxide (CTO), were compared to unmodified tin oxide sensors using amplitude and transient responses. For transient responses we used a family of features, derived from the exponential moving average (EMA), to characterize chemo-resistive responses. All sensors were tested simultaneously against 20 individual volatile compounds from four chemical groups. The responses of the two types of sensors showed some independence. The zeolite-modified CTO sensors discriminated compounds better using either amplitude response or EMA features and CTO-modified sensors also responded three times faster.
Numerical conversion of transient to harmonic response functions for linear viscoelastic materials.
Buschmann, M D
1997-02-01
Viscoelastic material behavior is often characterized using one of the three measurements: creep, stress-relaxation or dynamic sinusoidal tests. A two-stage numerical method was developed to allow representation of data from creep and stress-relaxation tests on the Fourier axis in the Laplace domain. The method assumes linear behavior and is theoretically applicable to any transient test which attains an equilibrium state. The first stage numerically resolves the Laplace integral to convert temporal stress and strain data, from creep or stress-relaxation, to the stiffness function, G(s), evaluated on the positive real axis in the Laplace domain. This numerical integration alone allows the direct comparison of data from transient experiments which attain a final equilibrium state, such as creep and stress relaxation, and allows such data to be fitted to models expressed in the Laplace domain. The second stage of this numerical procedure maps the stiffness function, G(s), from the positive real axis to the positive imaginary axis to reveal the harmonic response function, or dynamic stiffness, G(j omega). The mapping for each angular frequency, s, is accomplished by fitting a polynomial to a subset of G(s) centered around a particular value of s, substituting js for s and thereby evaluating G(j omega). This two-stage transformation circumvents previous numerical difficulties associated with obtaining Fourier transforms of the stress and strain time domain signals. The accuracy of these transforms is verified using model functions from poroelasticity, corresponding to uniaxial confined compression of an isotropic material and uniaxial unconfined compression of a transversely isotropic material. The addition of noise to the model data does not significantly deteriorate the transformed results and data points need not be equally spaced in time. To exemplify its potential utility, this two-stage transform is applied to experimental stress relaxation data to obtain the dynamic stiffness which is then compared to direct measurements of dynamic stiffness using steady-state sinusoidal tests of the same cartilage disk in confined compression. In addition to allowing calculation of the dynamic stiffness from transient tests and the direct comparison of experimental data from different tests, these numerical methods should aid in the experimental analysis of linear and nonlinear material behavior, and increase the speed of curve-fitting routines by fitting creep or stress relaxation data to models expressed in the Laplace domain.
Propulsion system mathematical model for a lift/cruise fan V/STOL aircraft
NASA Technical Reports Server (NTRS)
Cole, G. L.; Sellers, J. F.; Tinling, B. E.
1980-01-01
A propulsion system mathematical model is documented that allows calculation of internal engine parameters during transient operation. A non-realtime digital computer simulation of the model is presented. It is used to investigate thrust response and modulation requirements as well as the impact of duty cycle on engine life and design criteria. Comparison of simulation results with steady-state cycle deck calculations showed good agreement. The model was developed for a specific 3-fan subsonic V/STOL aircraft application, but it can be adapted for use with any similar lift/cruise V/STOL configuration.
Optical properties and electronic energy relaxation of metallic Au144(SR)60 nanoclusters.
Yi, Chongyue; Tofanelli, Marcus A; Ackerson, Christopher J; Knappenberger, Kenneth L
2013-12-04
Electronic energy relaxation of Au144(SR)60(q) ligand-protected nanoclusters, where SR = SC6H13 and q = -1, 0, +1, and +2, was examined using femtosecond time-resolved transient absorption spectroscopy. The observed differential transient spectra contained three distinct components: (1) transient bleaches at 525 and 600 nm, (2) broad visible excited-state absorption (ESA), and (3) stimulated emission (SE) at 670 nm. The bleach recovery kinetics depended upon the excitation pulse energy and were thus attributed to electron-phonon coupling typical of metallic nanostructures. The prominent bleach at 525 nm was assigned to a core-localized plasmon resonance (CLPR). ESA decay kinetics were oxidation-state dependent and could be described using a metal-sphere charging model. The dynamics, emission energy, and intensity of the SE peak exhibited dielectric-dependent responses indicative of Superatom charge transfer states. On the basis of these data, the Au144(SR)60 system is the smallest-known nanocluster to exhibit quantifiable electron dynamics and optical properties characteristic of metals.
Hansen, Katrina J; Favreau, John T; Gershlak, Joshua R; Laflamme, Michael A; Albrecht, Dirk R; Gaudette, Glenn R
2017-08-01
Differentiation of human pluripotent stem cells into cardiomyocytes (hPS-CMs) holds promise for myocardial regeneration therapies, drug discovery, and models of cardiac disease. Potential cardiotoxicities may affect hPS-CM mechanical contraction independent of calcium signaling. Herein, a method using an image capture system is described to measure hPS-CM contractility and intracellular calcium concurrently, with high spatial and temporal resolution. The image capture system rapidly alternates between brightfield and epifluorescent illumination of contracting cells. Mechanical contraction is quantified by a speckle tracking algorithm applied to brightfield image pairs, whereas calcium transients are measured by a fluorescent calcium reporter. This technique captured changes in contractile strain, calcium transients, and beat frequency of hPS-CMs over 21 days in culture, as well as acute responses to isoproterenol and Cytochalasin D. The technique described above can be applied without the need to alter the culture platform, allowing for determination of hPS-CM behavior over weeks in culture for drug discovery and myocardial regeneration applications.
Modeling Single-Event Transient Propagation in a SiGe BiCMOS Direct-Conversion Receiver
NASA Astrophysics Data System (ADS)
Ildefonso, Adrian; Song, Ickhyun; Tzintzarov, George N.; Fleetwood, Zachary E.; Lourenco, Nelson E.; Wachter, Mason T.; Cressler, John D.
2017-08-01
The propagation of single-event transient (SET) signals in a silicon-germanium direct-conversion receiver carrying modulated data is explored. A theoretical analysis of transient propagation, verified by simulation, is presented. A new methodology to characterize and quantify the impact of SETs in communication systems carrying modulated data is proposed. The proposed methodology uses a pulsed radiation source to induce distortions in the signal constellation. The error vector magnitude due to SETs can then be calculated to quantify errors. Two different modulation schemes were simulated: QPSK and 16-QAM. The distortions in the constellation diagram agree with the presented circuit theory. Furthermore, the proposed methodology was applied to evaluate the improvements in the SET response due to a known radiation-hardening-by-design (RHBD) technique, where the common-base device of the low-noise amplifier was operated in inverse mode. The proposed methodology can be a valid technique to determine the most sensitive parts of a system carrying modulated data.
Infrared radiometer for measuring thermophysical properties of wind tunnel models
NASA Technical Reports Server (NTRS)
Corwin, R. R.; Moorman, S. L.; Becker, E. C.
1978-01-01
An infrared radiometer is described which was developed to measure temperature rises of wind tunnel models undergoing transient heating over a temperature range of -17.8 C to 260 C. This radiometer interfaces directly with a system which measures the effective thermophysical property square root of rho ck. It has an output temperature fluctuation of 0.26 C at low temperatures and 0.07 C at high temperatures, and the output frequency response of the radiometer is from dc to 400 hertz.
NASA Technical Reports Server (NTRS)
Ross, H. D.; Schiller, D. N.; Disimile, P.; Sirignano, W. A.
1989-01-01
The temperature and velocity fields have been investigated for a single-phase gas system and a two-layer gas-and-liquid system enclosed in a circular cylinder being heated suddenly and nonuniformly from above. The transient response of the gas, liquid, and container walls was modelled numerically in normal and reduced gravity (10 to the -5 g). Verification of the model was accomplished via flow visualization experiments in 10 cm high by 10 cm diameter plexiglass cylinders.
Transfer function modeling of damping mechanisms in viscoelastic plates
NASA Technical Reports Server (NTRS)
Slater, J. C.; Inman, D. J.
1991-01-01
This work formulates a method for the modeling of material damping characteristics in plates. The Sophie German equation of classical plate theory is modified to incorporate hysteresis effects represented by complex stiffness using the transfer function approach proposed by Golla and Hughes, (1985). However, this procedure is not limited to this representation. The governing characteristic equation is decoupled through separation of variables, yielding a solution similar to that of undamped classical plate theory, allowing solution of the steady state as well as the transient response problem.
Heat Pipe Reactor Dynamic Response Tests: SAFE-100 Reactor Core Prototype
NASA Technical Reports Server (NTRS)
Bragg-Sitton, Shannon M.
2005-01-01
The SAFE-I00a test article at the NASA Marshall Space Flight Center was used to simulate a variety of potential reactor transients; the SAFEl00a is a resistively heated, stainless-steel heat-pipe (HP)-reactor core segment, coupled to a gas-flow heat exchanger (HX). For these transients the core power was controlled by a point kinetics model with reactivity feedback based on core average temperature; the neutron generation time and the temperature feedback coefficient are provided as model inputs. This type of non-nuclear test is expected to provide reasonable approximation of reactor transient behavior because reactivity feedback is very simple in a compact fast reactor (simple, negative, and relatively monotonic temperature feedback, caused mostly by thermal expansion) and calculations show there are no significant reactivity effects associated with fluid in the HP (the worth of the entire inventory of Na in the core is .
Rodgers, J.E.; Elebi, M.
2011-01-01
The 1994 Northridge earthquake caused brittle fractures in steel moment frame building connections, despite causing little visible building damage in most cases. Future strong earthquakes are likely to cause similar damage to the many un-retrofitted pre-Northridge buildings in the western US and elsewhere. Without obvious permanent building deformation, costly intrusive inspections are currently the only way to determine if major fracture damage that compromises building safety has occurred. Building instrumentation has the potential to provide engineers and owners with timely information on fracture occurrence. Structural dynamics theory predicts and scale model experiments have demonstrated that sudden, large changes in structure properties caused by moment connection fractures will cause transient dynamic response. A method is proposed for detecting the building-wide level of connection fracture damage, based on observing high-frequency, fracture-induced transient dynamic responses in strong motion accelerograms. High-frequency transients are short (<1 s), sudden-onset waveforms with frequency content above 25 Hz that are visually apparent in recorded accelerations. Strong motion data and damage information from intrusive inspections collected from 24 sparsely instrumented buildings following the 1994 Northridge earthquake are used to evaluate the proposed method. The method's overall success rate for this data set is 67%, but this rate varies significantly with damage level. The method performs reasonably well in detecting significant fracture damage and in identifying cases with no damage, but fails in cases with few fractures. Combining the method with other damage indicators and removing records with excessive noise improves the ability to detect the level of damage. ?? 2010 Elsevier B.V. All rights reserved.
[Cardiopulmonary dynamics during a maximal exertion test in Mexican endurance athletes].
Padilla, J; Martínez, E; Olvera, G; Ojeda Cruz, P; Caudillo Pérez, D
2000-01-01
To search for cardiopulmonary (CP) kinetic and dynamic differences between Mexican resistance athletes (RES = 10) and non athletes (NON = 19). From the expired volume (Ve), measured by an open circuit spirometry, we calculated both VO2 and VCO2 during stress test while the volunteer pedalled seated on an electronic cycloergometer that started at 50 W.2 min-1 followed by increments of 25 W.2 min-1 each, until VO2máx was reached. The exercise transient time course (min) response (VO2, VCO2, Ve and heart rate, HR; and also O2 pulse, PulO2) was transformed to seconds and modelled by computer using linear regression technique by the interactive minimum squares method, and the mean response time (MRT) was used as an overall kinetic CP parameter. The transient MRTs for VO2, VCO2 and Ve were slow in RES compared to NON. While the transient CP dynamics in NON lasted MRT_VO2 < (MRT_PulO2, MRT_FC) < MRT_VCO2 < MRT_Ve; the RES: both MRT_PulO2 and MRT_HR shifted to the right ((MRT_VO2, MRT_VCO2) < (MRT_PulO2, MRT_FC) < MRT_Ve). The relationships between the best sport profit mean velocity and both the MRT_VO2, MRT_VCO2 and MRT_PulO2 (GEK = gas exchange kinetics) showed fast_RES and slow_GEK, and slow_RES and fast_GEK. The transient CP kinetics was slow in RES compared NON. It is possible to distinguish cardiopulmonary kinetic differences among resistance athletes holding different sport profiles.
Wu, Yang; You, Huihui; Ma, Ping; Li, Li; Yuan, Ye; Li, Jinquan; Ye, Xin; Liu, Xudong; Yao, Hanchao; Chen, Ruchong; Lai, Kefang; Yang, Xu
2013-01-01
Objective Asthma is a complex pulmonary inflammatory disease characterized by the hyper-responsiveness, remodeling and inflammation of airways. Formaldehyde is a common indoor air pollutant that can cause asthma in people experiencing long-term exposure. The irritant effect and adjuvant effect are the two possible pathways of formaldehyde promoted asthma. Methodology/Principal Findings To explore the neural mechanisms and adjuvant effect of formaldehyde, 48 Balb/c mice in six experimental groups were exposed to (a) vehicle control; (b) ovalbumin; (c) formaldehyde (3.0 mg/m3); (d) ovalbumin+formaldehyde (3.0 mg/m3); (e) ovalbumin+formaldehyde (3.0 mg/m3)+HC-030031 (transient receptor potential ankyrin 1 antagonist); (f) ovalbumin+formaldehyde (3.0 mg/m3)+ capsazepine (transient receptor potential vanilloid 1 antagonist). Experiments were conducted after 4 weeks of combined exposure and 1-week challenge with aerosolized ovalbumin. Airway hyper-responsiveness, pulmonary tissue damage, eosinophil infiltration, and increased levels of interleukin-4, interleukin-6, interleukin-1β, immunoglobulin E, substance P and calcitonin gene-related peptide in lung tissues were found in the ovalbumin+formaldehyde (3.0 mg/m3) group compared with the values seen in ovalbumin -only immunized mice. Except for interleukin-1β levels, other changes in the levels of biomarker could be inhibited by HC-030031 and capsazepine. Conclusions/Significance Formaldehyde might be a key risk factor for the rise in asthma cases. Transient receptor potential ion channels and neuropeptides have important roles in formaldehyde promoted-asthma. PMID:23671638
Dewald, Oliver; Ren, Guofeng; Duerr, Georg D.; Zoerlein, Martin; Klemm, Christina; Gersch, Christine; Tincey, Sophia; Michael, Lloyd H.; Entman, Mark L.; Frangogiannis, Nikolaos G.
2004-01-01
Large animal models have provided much of the descriptive data regarding the cellular and molecular events in myocardial infarction and repair. The availability of genetically altered mice may provide a valuable tool for specific cellular and molecular dissection of these processes. In this report we compare closed chest models of canine and mouse infarction/reperfusion qualitatively and quantitatively for temporal, cellular, and spatial differences. Much like the canine model, reperfused mouse hearts are associated with marked induction of endothelial adhesion molecules, cytokines, and chemokines. Reperfused mouse infarcts show accelerated replacement of cardiomyocytes by granulation tissue leading to a thin mature scar at 14 days, when the canine infarction is still cellular and evolving. Infarcted mouse hearts demonstrate a robust but transient postreperfusion inflammatory reaction, associated with a rapid up-regulation of interleukin-10 and transforming growth factor-β. Unlike canine infarcts, infarcted mouse hearts show only transient macrophage infiltration and no significant mast cell accumulation. In correlation, the growth factor for macrophages, M-CSF, shows modest and transient up-regulation in the early days of reperfusion; and the obligate growth factor for mast cells, stem cell factor, SCF, is not induced. In summary, the postinfarction inflammatory response and resultant repair in the mouse heart shares many common characteristics with large mammalian species, but has distinct temporal and qualitative features. These important species-specific differences should be considered when interpreting findings derived from studies using genetically altered mice. PMID:14742270
NASA Technical Reports Server (NTRS)
Hippensteele, Steven A.; Poinsatte, Philip E.
1993-01-01
In this transient technique the preheated isothermal model wall simulates the classic one-dimensional, semi-infinite wall heat transfer conduction problem. By knowing the temperature of the air flowing through the model, the initial temperature of the model wall, and the surface cooling rate measured at any location with time (using the fast-response liquid-crystal patterns recorded on video tape), the heat transfer coefficient can be calculated for the color isothermal pattern produced. Although the test was run transiently, the heat transfer coefficients are for the steady-state case. The upstream thermal boundary condition was considered to be isothermal. This transient liquid-crystal heat-transfer technique was used in a transient air tunnel in which a square-inlet, 3-to-1 exit transition duct was placed. The duct was preheated prior to allowing room temperature air to be suddenly drawn through it. The resulting isothermal contours on the duct surfaces were revealed using a surface coating of thermochromic liquid crystals that display distinctive colors at particular temperatures. A video record was made of the temperature and time data for all points on the duct surfaces during each test. The duct surfaces were uniformly heated using two heating systems: the first was an automatic temperature-controlled heater blanket completely surrounding the test duct like an oven, and the second was an internal hot-air loop through the inside of the test duct. The hot-air loop path was confined inside the test duct by insulated heat dams located at the inlet and exit ends of the test duct. A recirculating fan moved hot air into the duct inlet, through the duct, out of the duct exit, through the oven, and back to the duct inlet. The temperature nonuniformity of the test duct model wall was held very small. Test results are reported for two inlet Reynolds numbers of 200,000 and 1,150,000 (based on the square-inlet hydraulic diameter) and two free-stream turbulence intensities of about 1 percent, which is typical of wind tunnels, and up to 20 percent (using a grid), which is typical of real engine conditions.
Revealing transient strain in geodetic data with Gaussian process regression
NASA Astrophysics Data System (ADS)
Hines, T. T.; Hetland, E. A.
2018-03-01
Transient strain derived from global navigation satellite system (GNSS) data can be used to detect and understand geophysical processes such as slow slip events and post-seismic deformation. Here we propose using Gaussian process regression (GPR) as a tool for estimating transient strain from GNSS data. GPR is a non-parametric, Bayesian method for interpolating scattered data. In our approach, we assume a stochastic prior model for transient displacements. The prior describes how much we expect transient displacements to covary spatially and temporally. A posterior estimate of transient strain is obtained by differentiating the posterior transient displacements, which are formed by conditioning the prior with the GNSS data. As a demonstration, we use GPR to detect transient strain resulting from slow slip events in the Pacific Northwest. Maximum likelihood methods are used to constrain a prior model for transient displacements in this region. The temporal covariance of our prior model is described by a compact Wendland covariance function, which significantly reduces the computational burden that can be associated with GPR. Our results reveal the spatial and temporal evolution of strain from slow slip events. We verify that the transient strain estimated with GPR is in fact geophysical signal by comparing it to the seismic tremor that is associated with Pacific Northwest slow slip events.
Transient and sustained neural responses to death-related linguistic cues
Shi, Zhenhao
2013-01-01
Recent research showed that perception of death-related vs death-unrelated linguistic cues produced increased frontoparietal activity but decreased insular activity. This study investigated (i) whether the increased frontoparietal and decreased insular activities are, respectively, associated with transient trial-specific processes of death-related linguistic cues and sustained death-related thought during death-relevance judgments on linguistic cues and (ii) whether the neural activity underlying death-related thought can predict individuals’ dispositional death anxiety. Participants were presented with death-related/unrelated words, life-related/unrelated words, and negative-valence/neutral words in separate sessions. Participants were scanned using functional magnetic resonance imaging while performing death-relevance, life-relevance, and valence judgments on the words, respectively. The contrast of death-related vs death-unrelated words during death-relevance judgments revealed transient increased activity in the left inferior parietal lobule, the right frontal eye field, and the right superior parietal lobule. The contrast of death-relevance judgments vs life-relevance/valence judgments showed decreased activity in the bilateral insula. The sustained insular activity was correlated with dispositional death anxiety, but only in those with weak transient frontoparietal responses to death-related words. Our results dissociate the transient and sustained neural responses to death-related linguistic cues and suggest that the combination of the transient and sustained neural activities can predict dispositional death anxiety. PMID:22422804
NASA Astrophysics Data System (ADS)
Griebel, Matt; Buleri, Christine; Baylor, Andrew; Gunnels, Steve; Hull, Charlie; Palunas, Povilas; Phillips, Mark
2016-07-01
The Magellan Telescopes are a set of twin 6.5 meter ground based optical/near-IR telescopes operated by the Carnegie Institution for Science at the Las Campanas Observatory (LCO) in Chile. The primary mirrors are f/1.25 paraboloids made of borosilicate glass and a honeycomb structure. The secondary mirror provides both f/11 and f/5 focal lengths with two Nasmyth, three auxiliary, and a Cassegrain port on the optical support structure (OSS). The telescopes have been in operation since 2000 and have experienced several small earthquakes with no damage. Measurement of in situ response of the telescopes to seismic events showed significant dynamic amplification, however, the response of the telescopes to a survival level earthquake, including component level forces, displacements, accelerations, and stresses were unknown. The telescopes are supported with hydrostatic bearings that can lift up under high seismic loading, thus causing a nonlinear response. For this reason, the typical response spectrum analysis performed to analyze a survival level seismic earthquake is not sufficient in determining the true response of the structure. Therefore, a nonlinear transient finite element analysis (FEA) of the telescope structure was performed to assess high risk areas and develop acceleration responses for future instrument design. Several configurations were considered combining different installed components and altitude pointing directions. A description of the models, methodology, and results are presented.
Electrowetting-driven spreading and jumping of drops in oil
NASA Astrophysics Data System (ADS)
Hong, Jiwoo; Lee, Sang Joon
2013-11-01
Electrowetting-based practical applications include digital microfluidics, liquid lenses, and reflective displays. Most of them are performed in water/oil system, because oil medium reduces the contact-angle hysteresis and prevents drop evaporation. In this study, the effects of drop volume, oil viscosity, and applied voltage on the dynamic behaviors of spreading drops, such as transition of spreading pattern and response time, are investigated. Interestingly, jumping phenomena of drops are observed in oil when the applied voltage is turned off after reaching the electrowetted equilibrium radius of drops. A numerical model to predict the transient behavior of jumping drops is formulated based on the phase-field method. The numerical results for the transient deformation of jumping drops show quantitative agreement with the experimental results.
Heat transfer rate and film cooling effectiveness measurements in a transient cascade
NASA Astrophysics Data System (ADS)
Schultz, D. L.; Oldfield, M. L. G.; Jones, T. V.
1980-09-01
A transient cascade useful for heat transfer rate measurements is briefly described. The facility employs a free piston which compresses the test gas to temperatures around 450 K and pressures of about 3.5 to 7.5 Atm. The model is initially at room temperature and it is necessary to attain the correct gas to wall temperature ratio. The exit Mach number is set by the inlet total pressure and the pressure in the exit dump tank. Thin film heat transfer gauges are used for the measurement of heat transfer rate, deposited on machineable glass ceramic blades. The inherently fast response of these transducers makes them useful for the investigation of boundary layer transition on blade surfaces and some typical results are included.
Chan, Roger W; Siegmund, Thomas; Zhang, Kai
2009-12-01
Accurate characterization of biomechanical characteristics of the vocal fold is critical for understanding the regulation of vocal fundamental frequency (F(0)), which depends on the active control of the intrinsic laryngeal muscles as well as the passive biomechanical response of the vocal fold lamina propria. Specifically, the tissue stress-strain response and viscoelastic properties under cyclic tensile deformation are relevant, when the vocal folds are subjected to length and tension changes due to posturing. This paper describes a constitutive modeling approach quantifying the relationship between vocal fold stress and strain (or stretch), and establishes predictions of F(0) with the string model of phonation based on the constitutive parameters. Results indicated that transient and time-dependent changes in F(0), including global declinations in declarative sentences, as well as local F(0) overshoots and undershoots, can be partially attributed to the time-dependent viscoplastic response of the vocal fold cover.
NASA Technical Reports Server (NTRS)
Cheng, Rendy P.; Tischler, Mark B.; Celi, Roberto
2006-01-01
This research describes a new methodology for the extraction of a high-order, linear time invariant model, which allows the periodicity of the helicopter response to be accurately captured. This model provides the needed level of dynamic fidelity to permit an analysis and optimization of the AFCS and HHC algorithms. The key results of this study indicate that the closed-loop HHC system has little influence on the AFCS or on the vehicle handling qualities, which indicates that the AFCS does not need modification to work with the HHC system. However, the results show that the vibration response to maneuvers must be considered during the HHC design process, and this leads to much higher required HHC loop crossover frequencies. This research also demonstrates that the transient vibration responses during maneuvers can be reduced by optimizing the closed-loop higher harmonic control algorithm using conventional control system analyses.
Liu, W M; Chu, W M; Choudary, P V; Schmid, C W
1995-01-01
The abundance of Alu RNA is transiently increased by heat shock in human cell lines. This effect is specific to Alu repeats among Pol III transcribed genes, since the abundance of 7SL, 7SK, 5S and U6 RNAs is essentially unaffected by heat shock. The rapid induction of Alu expression precedes the heat shock induction of mRNAs for the ubiquitin and HSP 70 heat shock genes. Heat shock mimetics also transiently induce Alu expression indicating that increased Alu expression is a general cell-stress response. Cycloheximide treatment rapidly and transiently increases the abundance of Alu RNA. Again, compared with other genes transcribed by Pol III, this increase is specific to Alu. However, as distinguished from the cell stress response, cycloheximide does not induce expression of HSP 70 and ubiquitin mRNAs. Puromycin also increases Alu expression, suggesting that this response is generally caused by translational inhibition. The response of mammalian SINEs to cell stress and translational inhibition is not limited to SINEs which are Alu homologues. Heat shock and cycloheximide each transiently induce Pol III directed expression of B1 and B2 RNAs in mouse cells and C-element RNA in rabbit cells. Together, these three species exemplify the known SINE composition of placental mammals, suggesting that mammalian SINEs are similarly regulated and may serve a common function. Images PMID:7784180
The dynamics of a flexible bladed disc on a flexible rotor in a two-rotor system
NASA Technical Reports Server (NTRS)
Gallardo, V. C.; Stallone, M. J.
1984-01-01
This paper describes the development of the analysis of the transient dynamic response of a bladed disk on a flexible rotor. The rotating flexible bladed disk is considered as a module in a complete turbine engine structure. The analysis of the flexible bladed disk (FBD) module is developed for the non-equilibrated one-diameter axial mode. The FBD motion is considered as a sum of two standing axial waves constrained to the rotor. The FBD is coupled inertially and gyroscopically to its rotor support, and indirectly through connecting elements, to the adjacent rotor and/or other supporting structures. Incorporated in the basic Turbine Engine Transient Response Analysis program (TETRA), the FBD module is demonstrated with a two-rotor model where the FBD can be excited into resonance by an unbalance in the adjacent rotor and at a frequency equal to the differential rotor speed. The FBD module also allows the analysis of two flexible bladed disks in the same rotor.
Molecular mechanism of emotional stress-induced and catecholamine-induced heart attack.
Ueyama, Takashi; Senba, Emiko; Kasamatsu, Ken; Hano, Takuzo; Yamamoto, Katsuhiro; Nishio, Ichiro; Tsuruo, Yoshihiro; Yoshida, Ken-ichi
2003-01-01
Emotional or physical stress triggers 'tako-tsubo' cardiomyopathy or 'transient left ventricular apical ballooning', but the pathogenesis is unclear. In response to the immobilization stress of rats, a useful model of emotional stress, rapid activation of p44/p42 mitogen-activated protein kinase was observed in the heart, followed by a transient upregulation of immediate early genes in the smooth muscle cells of coronary arteries, the endothelial cells and the myocardium. Heat shock protein 70 was induced in the aortic and coronary arterial smooth muscle cells and in the myocardium. Natriuretic peptide genes were also upregulated in the myocardium. Sequential gene expression can be considered as an adaptive response to emotional stress. Blocking of both alpha-adrenoceptors and beta-adrenoceptors eliminated the upregulation of immediate early genes induced by stress, while alpha-agonists and beta-agonists upregulated immediate early genes in the perfused heart. Activation of alpha-adrenoceptors and beta-adrenoceptors is the primary trigger of emotional stress-induced molecular changes in the heart.