Optical Diagnostics of Multi-Gap Gas Switches for Linear Transformer Drivers

NASA Astrophysics Data System (ADS)

Sheng, Liang; Li, Yang; Sun, Tieping; Cong, Peitian; Zhang, Mei; Peng, Bodong; Zhao, Jizhen; Yue, Zhiqin; Wei, Fuli; Yuan, Yuan

2014-07-01

The trigger characteristics of a multi-gap gas switch with double insulating layers, a square-groove electrode supporter and a UV pre-ionizing structure are investigated aided by a high sensitivity fiber-bundle array detector, a UV fiber detector, and a framing camera, in addition to standard electrical diagnostics. The fiber-bundle-array detector is used to track the turn-on sequence of each electrode gap at a timing precision of 0.6 ns. Each fiber bundle, including five fibers with different azimuth angles, aims at the whole emitting area of each electrode gap and is fed to a photomultiplier tube. The UV fiber detector with a spectrum response of 260-320 nm, including a fused-quartz fiber of 200 μm in diameter and a solar-blinded photomultiplier tube, is adopted to study the effect of UV pre-ionizing on trigger characteristics. The framing camera, with a capacity of 4 frames per shot and an exposure time of 5 ns, is employed to capture the evolution of channel arcs. Based on the turn-on light signal of each electrode gap, the breakdown delay is divided into statistical delay and formative delay. A decrease in both of them, a smaller switch jitter and more channel arcs are observed with lower gas pressure. An increase in trigger voltage can reduce the statistical delay and its jitter, while higher trigger voltage has a relatively small influence on the formative delay and the number of channel arcs. With the UV pre-ionizing structure at 0.24 MPa gas pressure and 60 kV trigger voltage, the statistical delay and its jitter can be reduced by 1.8 ns and 0.67 ns, while the formative delay and its jitter can only be reduced by 0.5 ns and 0.25 ns.

Temporally Shaped Current Pulses on a Two-Cavity Linear Transformer Driver System

DTIC Science & Technology

2011-06-01

essentially at a fraction of the total switch voltage. Non-uniform corona current characteristics of the different corona needles could cause imperfect...withstand twice the capacitor voltage. A pulse applied to the switch trigger electrodes initiate closure of each switch. We have arranged triggering in...internal cavity potential to ground, allows the trigger electrode of the spark gaps to be at ground potential during charging, and eliminates a

NDAS Hardware Translation Layer Development

NASA Technical Reports Server (NTRS)

Nazaretian, Ryan N.; Holladay, Wendy T.

2011-01-01

The NASA Data Acquisition System (NDAS) project is aimed to replace all DAS software for NASA s Rocket Testing Facilities. There must be a software-hardware translation layer so the software can properly talk to the hardware. Since the hardware from each test stand varies, drivers for each stand have to be made. These drivers will act more like plugins for the software. If the software is being used in E3, then the software should point to the E3 driver package. If the software is being used at B2, then the software should point to the B2 driver package. The driver packages should also be filled with hardware drivers that are universal to the DAS system. For example, since A1, A2, and B2 all use the Preston 8300AU signal conditioners, then the driver for those three stands should be the same and updated collectively.

Steering disturbance rejection using a physics-based neuromusculoskeletal driver model

NASA Astrophysics Data System (ADS)

Mehrabi, Naser; Sharif Razavian, Reza; McPhee, John

2015-10-01

The aim of this work is to develop a comprehensive yet practical driver model to be used in studying driver-vehicle interactions. Drivers interact with their vehicle and the road through the steering wheel. This interaction forms a closed-loop coupled human-machine system, which influences the driver's steering feel and control performance. A hierarchical approach is proposed here to capture the complexity of the driver's neuromuscular dynamics and the central nervous system in the coordination of the driver's upper extremity activities, especially in the presence of external disturbance. The proposed motor control framework has three layers: the first (or the path planning) plans a desired vehicle trajectory and the required steering angles to perform the desired trajectory; the second (or the musculoskeletal controller) actuates the musculoskeletal arm to rotate the steering wheel accordingly; and the final layer ensures the precision control and disturbance rejection of the motor control units. The physics-based driver model presented here can also provide insights into vehicle control in relaxed and tensed driving conditions, which are simulated by adjusting the driver model parameters such as cognition delay and muscle co-contraction dynamics.

Distributed solid state programmable thermostat/power controller

NASA Technical Reports Server (NTRS)

Smith, Dennis A. (Inventor); Alexander, Jane C. (Inventor); Howard, David E. (Inventor)

2008-01-01

A self-contained power controller having a power driver switch, programmable controller, communication port, and environmental parameter measuring device coupled to a controllable device. The self-contained power controller needs only a single voltage source to power discrete devices, analog devices, and the controlled device. The programmable controller has a run mode which, when selected, upon the occurrence of a trigger event changes the state of a power driver switch and wherein the power driver switch is maintained by the programmable controller at the same state until the occurrence of a second event.

Value of peripheral nodes in controlling multilayer scale-free networks

NASA Astrophysics Data System (ADS)

Zhang, Yan; Garas, Antonios; Schweitzer, Frank

2016-01-01

We analyze the controllability of a two-layer network, where driver nodes can be chosen randomly only from one layer. Each layer contains a scale-free network with directed links and the node dynamics depends on the incoming links from other nodes. We combine the in-degree and out-degree values to assign an importance value w to each node, and distinguish between peripheral nodes with low w and central nodes with high w . Based on numerical simulations, we find that the controllable part of the network is larger when choosing low w nodes to connect the two layers. The control is as efficient when peripheral nodes are driver nodes as it is for the case of more central nodes. However, if we assume a cost to utilize nodes that is proportional to their overall degree, utilizing peripheral nodes to connect the two layers or to act as driver nodes is not only the most cost-efficient solution, it is also the one that performs best in controlling the two-layer network among the different interconnecting strategies we have tested.

Drivers of Emerging Infectious Disease Events as a Framework for Digital Detection.

PubMed

Olson, Sarah H; Benedum, Corey M; Mekaru, Sumiko R; Preston, Nicholas D; Mazet, Jonna A K; Joly, Damien O; Brownstein, John S

2015-08-01

The growing field of digital disease detection, or epidemic intelligence, attempts to improve timely detection and awareness of infectious disease (ID) events. Early detection remains an important priority; thus, the next frontier for ID surveillance is to improve the recognition and monitoring of drivers (antecedent conditions) of ID emergence for signals that precede disease events. These data could help alert public health officials to indicators of elevated ID risk, thereby triggering targeted active surveillance and interventions. We believe that ID emergence risks can be anticipated through surveillance of their drivers, just as successful warning systems of climate-based, meteorologically sensitive diseases are supported by improved temperature and precipitation data. We present approaches to driver surveillance, gaps in the current literature, and a scientific framework for the creation of a digital warning system. Fulfilling the promise of driver surveillance will require concerted action to expand the collection of appropriate digital driver data.

Drivers of deep-water renewal events observed over 13 years in the South Basin of Lake Baikal

NASA Astrophysics Data System (ADS)

Tsimitri, Chrysanthi; Rockel, Burkhardt; Wüest, Alfred; Budnev, Nikolay M.; Sturm, Michael; Schmid, Martin

2015-03-01

Lake Baikal, with a depth of 1637 m, is characterized by deep-water intrusions that bridge the near-surface layer to the hypolimnion. These episodic events transfer heat and oxygen over large vertical scales and maintain the permanent temperature stratified deep-water status of the lake. Here we evaluate a series of intrusion events that reached the bottom of the lake in terms of the stratification and the wind conditions under which they occurred and provide a new insight into the triggering mechanisms. We make use of long-term temperature and current meter data (2000-2013) recorded in the South Basin of the lake combined with wind data produced with a regional downscaling of the global NCEP-RA1 reanalysis product. A total of 13 events were observed during which near-surface cold water reached the bottom of the South Basin at 1350 m depth. We found that the triggering mechanism of the events is related to the time of the year that they take place. We categorized the events in three groups: (1) winter events, observed shortly before the complete ice cover of the lake that are triggered by Ekman coastal downwelling, (2) under-ice events, and (3) spring events, that show no correlation to the wind conditions and are possibly connected to the increased spring outflow of the Selenga River. This article was corrected on 18 MAR 2015. See the end of the full text for details.

Acoustically induced slip in sheared granular layers: Application to dynamic earthquake triggering: TRIGGERED SLIP IN SHEARED GRANULAR GOUGE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ferdowsi, Behrooz; Griffa, Michele; Guyer, Robert A.

A fundamental mystery in earthquake physics is “how can an earthquake be triggered by distant seismic sources?” We use discrete element method simulations of a granular layer, during stick slip, that is subject to transient vibrational excitation to gain further insight into the physics of dynamic earthquake triggering. We also observe delayed triggering of slip in the granular gouge, using Coulomb friction law for grains interaction. We find that at a critical vibrational amplitude (strain) there is an abrupt transition from negligible time-advanced slip (clock advance) to full clock advance; i.e., transient vibration and triggered slip are simultaneous. Moreover, themore » critical strain is of order 10 -6, similar to observations in the laboratory and in Earth. The transition is related to frictional weakening of the granular layer due to a dramatic decrease in coordination number and the weakening of the contact force network. Associated with this frictional weakening is a pronounced decrease in the elastic modulus of the layer. The study has important implications for mechanisms of triggered earthquakes and induced seismic events and points out the underlying processes in response of the fault gouge to dynamic transient stresses.« less

Acoustically induced slip in sheared granular layers: Application to dynamic earthquake triggering: TRIGGERED SLIP IN SHEARED GRANULAR GOUGE

DOE PAGES

Ferdowsi, Behrooz; Griffa, Michele; Guyer, Robert A.; ...

2015-11-19

A fundamental mystery in earthquake physics is “how can an earthquake be triggered by distant seismic sources?” We use discrete element method simulations of a granular layer, during stick slip, that is subject to transient vibrational excitation to gain further insight into the physics of dynamic earthquake triggering. We also observe delayed triggering of slip in the granular gouge, using Coulomb friction law for grains interaction. We find that at a critical vibrational amplitude (strain) there is an abrupt transition from negligible time-advanced slip (clock advance) to full clock advance; i.e., transient vibration and triggered slip are simultaneous. Moreover, themore » critical strain is of order 10 -6, similar to observations in the laboratory and in Earth. The transition is related to frictional weakening of the granular layer due to a dramatic decrease in coordination number and the weakening of the contact force network. Associated with this frictional weakening is a pronounced decrease in the elastic modulus of the layer. The study has important implications for mechanisms of triggered earthquakes and induced seismic events and points out the underlying processes in response of the fault gouge to dynamic transient stresses.« less

How the propagation of heat-flux modulations triggers E × B flow pattern formation.

PubMed

Kosuga, Y; Diamond, P H; Gürcan, O D

2013-03-08

We propose a novel mechanism to describe E×B flow pattern formation based upon the dynamics of propagation of heat-flux modulations. The E × B flows of interest are staircases, which are quasiregular patterns of strong, localized shear layers and profile corrugations interspersed between regions of avalanching. An analogy of staircase formation to jam formation in traffic flow is used to develop an extended model of heat avalanche dynamics. The extension includes a flux response time, during which the instantaneous heat flux relaxes to the mean heat flux, determined by symmetry constraints. The response time introduced here is the counterpart of the drivers' response time in traffic, during which drivers adjust their speed to match the background traffic flow. The finite response time causes the growth of mesoscale temperature perturbations, which evolve to form profile corrugations. The length scale associated with the maximum growth rate scales as Δ(2) ~ (v(thi)/λT(i))ρ(i)sqrt[χ(neo)τ], where λT(i) is a typical heat pulse speed, χ(neo) is the neoclassical thermal diffusivity, and τ is the response time of the heat flux. The connection between the scale length Δ(2) and the staircase interstep scale is discussed.

GERICOS: A Generic Framework for the Development of On-Board Software

NASA Astrophysics Data System (ADS)

Plasson, P.; Cuomo, C.; Gabriel, G.; Gauthier, N.; Gueguen, L.; Malac-Allain, L.

2016-08-01

This paper presents an overview of the GERICOS framework (GEneRIC Onboard Software), its architecture, its various layers and its future evolutions. The GERICOS framework, developed and qualified by LESIA, offers a set of generic, reusable and customizable software components for the rapid development of payload flight software. The GERICOS framework has a layered structure. The first layer (GERICOS::CORE) implements the concept of active objects and forms an abstraction layer over the top of real-time kernels. The second layer (GERICOS::BLOCKS) offers a set of reusable software components for building flight software based on generic solutions to recurrent functionalities. The third layer (GERICOS::DRIVERS) implements software drivers for several COTS IP cores of the LEON processor ecosystem.

High performance thyratron driver with low jitter.

PubMed

Verma, Rishi; Lee, P; Springham, S V; Tan, T L; Rawat, R S

2007-08-01

We report the design and development of insulated gate bipolar junction transistor based high performance driver for operating thyratrons in grounded grid mode. With careful design, the driver meets the specification of trigger output pulse rise time less than 30 ns, jitter less than +/-1 ns, and time delay less than 160 ns. It produces a -600 V pulse of 500 ns duration (full width at half maximum) at repetition rate ranging from 1 Hz to 1.14 kHz. The developed module also facilitates heating and biasing units along with protection circuitry in one complete package.

Altering rainfall patterns through aerosol dispersion

NASA Astrophysics Data System (ADS)

Emetere, M. E.; Bakeko, M.; Onyechekwa, L.; Ayara, W.

2017-05-01

The possibility of recirculation mechanism on rainfall patterns is salient for sustenance of the human race through agricultural produce. The peculiarity of the lower atmosphere of south west region of Nigeria was explored using theoretical and experimental approach. In the theoretical approach, the reconstruction of 1D model as an extraction from the 3D aerosol dispersion model was used to examine the physics of the recirculation theory. The experimental approach which consists of obtaining dataset from ground instruments was used to provide on-site guide for developing the new recirculation theories. The data set was obtained from the Davis weather station, Nigeria Meteorological agency and Multi-angle Imaging Spectro-radiometer (MISR). We looked at the main drivers of recirculation and propounded that recirculation is a complex process which triggers a reordering of the mixing layer- a key factor for initiating the type of rainfall in this region.

Distinct microbial communities in the active and permafrost layers on the Tibetan Plateau.

PubMed

Chen, Yong-Liang; Deng, Ye; Ding, Jin-Zhi; Hu, Hang-Wei; Xu, Tian-Le; Li, Fei; Yang, Gui-Biao; Yang, Yuan-He

2017-12-01

Permafrost represents an important understudied genetic resource. Soil microorganisms play important roles in regulating biogeochemical cycles and maintaining ecosystem function. However, our knowledge of patterns and drivers of permafrost microbial communities is limited over broad geographic scales. Using high-throughput Illumina sequencing, this study compared soil bacterial, archaeal and fungal communities between the active and permafrost layers on the Tibetan Plateau. Our results indicated that microbial alpha diversity was significantly higher in the active layer than in the permafrost layer with the exception of fungal Shannon-Wiener index and Simpson's diversity index, and microbial community structures were significantly different between the two layers. Our results also revealed that environmental factors such as soil fertility (soil organic carbon, dissolved organic carbon and total nitrogen contents) were the primary drivers of the beta diversity of bacterial, archaeal and fungal communities in the active layer. In contrast, environmental variables such as the mean annual precipitation and total phosphorus played dominant roles in driving the microbial beta diversity in the permafrost layer. Spatial distance was important for predicting the bacterial and archaeal beta diversity in both the active and permafrost layers, but not for fungal communities. Collectively, these results demonstrated different driving factors of microbial beta diversity between the active layer and permafrost layer, implying that the drivers of the microbial beta diversity observed in the active layer cannot be used to predict the biogeographic patterns of the microbial beta diversity in the permafrost layer. © 2017 John Wiley & Sons Ltd.

Energy recapture through deceleration - regenerative braking in electric vehicles from a user perspective.

PubMed

Cocron, Peter; Bühler, Franziska; Franke, Thomas; Neumann, Isabel; Dielmann, Benno; Krems, Josef F

2013-01-01

We report results from a 1-year field study (N = 80) on user interactions with regenerative braking in electric vehicles. Designed to recapture energy in vehicles with electric powertrains, regenerative braking has an important influence on both the task of driving and energy consumption. Results from user assessments and data from onboard data loggers indicate that most drivers quickly learned to interact with the system, which was triggered via accelerator. Further, conventional braking manoeuvres decreased significantly as the majority of deceleration episodes could only be executed through regenerative braking. Still, some drivers reported difficulties when adapting to the system. These difficulties could be addressed by offering different levels of regeneration so that the intensity of the deceleration could be individually modified. In general, the system is trusted and regarded as a valuable tool for prolonging range. Regenerative braking in electric vehicles has direct implications for the driving task. We found that drivers quickly learn to use and accept a system, which is triggered via accelerator. For those reporting difficulties in the interaction, it appears reasonable to integrate options to customise or switch off the system.

UWB multi-burst transmit driver for averaging receivers

DOEpatents

Dallum, Gregory E

2012-11-20

A multi-burst transmitter for ultra-wideband (UWB) communication systems generates a sequence of precisely spaced RF bursts from a single trigger event. There are two oscillators in the transmitter circuit, a gated burst rate oscillator and a gated RF burst or RF power output oscillator. The burst rate oscillator produces a relatively low frequency, i.e., MHz, square wave output for a selected transmit cycle, and drives the RF burst oscillator, which produces RF bursts of much higher frequency, i.e., GHz, during the transmit cycle. The frequency of the burst rate oscillator sets the spacing of the RF burst packets. The first oscillator output passes through a bias driver to the second oscillator. The bias driver conditions, e.g., level shifts, the signal from the first oscillator for input into the second oscillator, and also controls the length of each RF burst. A trigger pulse actuates a timing circuit, formed of a flip-flop and associated reset time delay circuit, that controls the operation of the first oscillator, i.e., how long it oscillates (which defines the transmit cycle).

Reversible Modulation of DNA-Based Hydrogel Shapes by Internal Stress Interactions.

PubMed

Hu, Yuwei; Kahn, Jason S; Guo, Weiwei; Huang, Fujian; Fadeev, Michael; Harries, Daniel; Willner, Itamar

2016-12-14

We present the assembly of asymmetric two-layer hybrid DNA-based hydrogels revealing stimuli-triggered reversibly modulated shape transitions. Asymmetric, linear hydrogels that include layer-selective switchable stimuli-responsive elements that control the hydrogel stiffness are designed. Trigger-induced stress in one of the layers results in the bending of the linear hybrid structure, thereby minimizing the elastic free energy of the systems. The removal of the stress by a counter-trigger restores the original linear bilayer hydrogel. The stiffness of the DNA hydrogel layers is controlled by thermal, pH (i-motif), K + ion/crown ether (G-quadruplexes), chemical (pH-doped polyaniline), or biocatalytic (glucose oxidase/urease) triggers. A theoretical model relating the experimental bending radius of curvatures of the hydrogels with the Young's moduli and geometrical parameters of the hydrogels is provided. Promising applications of shape-regulated stimuli-responsive asymmetric hydrogels include their use as valves, actuators, sensors, and drug delivery devices.

A novel integrated chassis controller for full drive-by-wire vehicles

NASA Astrophysics Data System (ADS)

Song, Pan; Tomizuka, Masayoshi; Zong, Changfu

2015-02-01

In this paper, a systematic design with multiple hierarchical layers is adopted in the integrated chassis controller for full drive-by-wire vehicles. A reference model and the optimal preview acceleration driver model are utilised in the driver control layer to describe and realise the driver's anticipation of the vehicle's handling characteristics, respectively. Both the sliding mode control and terminal sliding mode control techniques are employed in the vehicle motion control (MC) layer to determine the MC efforts such that better tracking performance can be attained. In the tyre force allocation layer, a polygonal simplification method is proposed to deal with the constraints of the tyre adhesive limits efficiently and effectively, whereby the load transfer due to both roll and pitch is also taken into account which directly affects the constraints. By calculating the motor torque and steering angle of each wheel in the executive layer, the total workload of four wheels is minimised during normal driving, whereas the MC efforts are maximised in extreme handling conditions. The proposed controller is validated through simulation to improve vehicle stability and handling performance in both open- and closed-loop manoeuvres.

Development of modular scalable pulsed power systems for high power magnetized plasma experiments

NASA Astrophysics Data System (ADS)

Bean, I. A.; Weber, T. E.; Adams, C. S.; Henderson, B. R.; Klim, A. J.

2017-10-01

New pulsed power switches and trigger drivers are being developed in order to explore higher energy regimes in the Magnetic Shock Experiment (MSX) at Los Alamos National Laboratory. To achieve the required plasma velocities, high-power (approx. 100 kV, 100s of kA), high charge transfer (approx. 1 C), low-jitter (few ns) gas switches are needed. A study has been conducted on the effects of various electrode geometries and materials, dielectric media, and triggering strategies; resulting in the design of a low-inductance annular field-distortion switch, optimized for use with dry air at 90 psig, and triggered by a low-jitter, rapid rise-time solid-state Linear Transformer Driver. The switch geometry and electrical characteristics are designed to be compatible with Syllac style capacitors, and are intended to be deployed in modular configurations. The scalable nature of this approach will enable the rapid design and implementation of a wide variety of high-power magnetized plasma experiments. This work is supported by the U.S. Department of Energy, National Nuclear Security Administration. Approved for unlimited release, LA-UR-17-2578.

The Influence of Individual Driver Characteristics on Congestion Formation

NASA Astrophysics Data System (ADS)

Wang, Lanjun; Zhang, Hao; Meng, Huadong; Wang, Xiqin

Previous works have pointed out that one of the reasons for the formation of traffic congestion is instability in traffic flow. In this study, we investigate theoretically how the characteristics of individual drivers influence the instability of traffic flow. The discussions are based on the optimal velocity model, which has three parameters related to individual driver characteristics. We specify the mappings between the model parameters and driver characteristics in this study. With linear stability analysis, we obtain a condition for when instability occurs and a constraint about how the model parameters influence the unstable traffic flow. Meanwhile, we also determine how the region of unstable flow densities depends on these parameters. Additionally, the Langevin approach theoretically validates that under the constraint, the macroscopic characteristics of the unstable traffic flow becomes a mixture of free flows and congestions. All of these results imply that both overly aggressive and overly conservative drivers are capable of triggering traffic congestion.

Recognising safety critical events: can automatic video processing improve naturalistic data analyses?

PubMed

Dozza, Marco; González, Nieves Pañeda

2013-11-01

New trends in research on traffic accidents include Naturalistic Driving Studies (NDS). NDS are based on large scale data collection of driver, vehicle, and environment information in real world. NDS data sets have proven to be extremely valuable for the analysis of safety critical events such as crashes and near crashes. However, finding safety critical events in NDS data is often difficult and time consuming. Safety critical events are currently identified using kinematic triggers, for instance searching for deceleration below a certain threshold signifying harsh braking. Due to the low sensitivity and specificity of this filtering procedure, manual review of video data is currently necessary to decide whether the events identified by the triggers are actually safety critical. Such reviewing procedure is based on subjective decisions, is expensive and time consuming, and often tedious for the analysts. Furthermore, since NDS data is exponentially growing over time, this reviewing procedure may not be viable anymore in the very near future. This study tested the hypothesis that automatic processing of driver video information could increase the correct classification of safety critical events from kinematic triggers in naturalistic driving data. Review of about 400 video sequences recorded from the events, collected by 100 Volvo cars in the euroFOT project, suggested that drivers' individual reaction may be the key to recognize safety critical events. In fact, whether an event is safety critical or not often depends on the individual driver. A few algorithms, able to automatically classify driver reaction from video data, have been compared. The results presented in this paper show that the state of the art subjective review procedures to identify safety critical events from NDS can benefit from automated objective video processing. In addition, this paper discusses the major challenges in making such video analysis viable for future NDS and new potential applications for NDS video processing. As new NDS such as SHRP2 are now providing the equivalent of five years of one vehicle data each day, the development of new methods, such as the one proposed in this paper, seems necessary to guarantee that these data can actually be analysed. Copyright © 2013 Elsevier Ltd. All rights reserved.

Temporal separation and self-rating of alertness as indicators of driver fatigue in commercial motor vehicle operators.

PubMed

Belz, Steven M; Robinson, Gary S; Casali, John G

2004-01-01

This on-road field investigation employed, for the first time, a completely automated trigger-based data collection system capable of evaluating driver performance in an extended-duration real-world commercial motor vehicle environment. The study examined the use of self-assessment of fatigue (Karolinska Sleepiness Scale) and temporal separation (minimum time to collision, minimum headway, and mean headway) as indicators of driver fatigue. Without exception, the correlation analyses for both the self-rating of alertness and temporal separation yielded models low in associative ability; neither metric was found to be a valid indicator of driver fatigue. In addition, based upon the data collected for this research, preliminary evidence suggests that driver fatigue onset within a real-world driving environment does not appear to follow the standard progression of events associated with the onset of fatigue within a simulated driving environment. Application of this research includes the development of an on-board driver performance/fatigue monitoring system that could potentially assist drivers in identifying the onset of fatigue.

An empirical assessment of driver motivation and emotional states in perceived safety margins under varied driving conditions.

PubMed

Zhang, Yu; Kaber, David B

2013-01-01

Motivation models in driving behaviour postulate that driver motives and emotional states dictate risk tolerance under various traffic conditions. The present study used time and driver performance-based payment systems to manipulate motivation and risk-taking behaviour. Ten participants drove to a predefined location in a simulated driving environment. Traffic patterns (density and velocity) were manipulated to cause driver behaviour adjustments due to the need to conform with the social norms of the roadway. The driving environment complexity was investigated as a mediating factor in risk tolerance. Results revealed the performance-based payment system to closely relate to risk-taking behaviour as compared with the time-based payment system. Drivers conformed with social norms associated with specific traffic patterns. Higher roadway complexity led to a more conservative safety margins and speeds. This research contributes to the further development of motivational models of driver behaviour. This study provides empirical justification for two motivation factors in driver risk-taking decisions, including compliance with social norm and emotions triggered by incentives. Environment complexity was identified as a mediating factor in motivational behaviour model. This study also recommended safety margin measures sensitive to changes in driver risk tolerance.

Spark gaps synchronization using electrical trigger pulses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Agarwal, Ritu; Saroj, P.C.; Sharma, Archana

In pulse power systems, it is required to have synchronized triggering of two or more high voltage spark gaps capable of switching large currents, using electrical trigger pulses. This paper intends to study the synchronization of spark gaps using electrical trigger. The trigger generator consists of dc supply, IGBT switch and driver circuit which generates 8kV, 400ns (FWHM) pulses. The experiment was carried out using two 0.15uF/50kV energy storage capacitors charged to 12kV and discharged through stainless steel spark gaps of diameter 9 mm across 10 ohm non inductive load. The initial experiment shows that synchronization has been achieved withmore » jitter of 50 to 100ns. Further studies carried out to reduce the jitter time by varying various electrical parameters will be presented. (author)« less

Low-jitter high-power thyristor array pulse driver and generator

DOEpatents

Hanks, Roy L.

2002-01-01

A method and apparatus for generating low-jitter, high-voltage and high-current pulses for driving low impedance loads such as detonator fuses uses a MOSFET driver which, when triggered, discharges a high-voltage pre-charged capacitor into the primary of a toroidal current-multiplying transformer with multiple isolated secondary windings. The secondary outputs are suitable for driving an array of thyristors that discharge a precharged high-voltage capacitor and thus generating the required high-voltage and high-current pulse.

Is the useful field of view a good predictor of at-fault crash risk in elderly Japanese drivers?

PubMed

Sakai, Hiroyuki; Uchiyama, Yuji; Takahara, Miwa; Doi, Shun'ichi; Kubota, Fumiko; Yoshimura, Takayoshi; Tachibana, Atsumichi; Kurahashi, Tetsuo

2015-05-01

Although age-related decline in the useful field of view (UFOV) is well recognized as a risk factor for at-fault crash involvement in elderly drivers, there is still room to study its applicability to elderly Japanese drivers. In the current study, we thus examined the relationship between UFOV and at-fault crash history in an elderly Japanese population. We also explored whether potential factors that create awareness of reduced driving fitness could be a trigger for the self-regulation of driving in elderly drivers. We measured UFOV and at-fault crash history from 151 community-dwelling Japanese aged 60 years or older, and compared UFOV of at-fault crash-free and crash-involved drivers. We also measured self-evaluated driving style using a questionnaire. UFOV in crash-involved drivers was significantly lower than that in crash-free drivers. No significant difference was found in self-evaluated driving style between crash-free and crash-involved drivers. In addition, there was no significant association between UFOV and self-evaluated driving style. The present study showed that UFOV is a good predictor of at-fault crash risk in elderly Japanese drivers. Furthermore, our data imply that it might be difficult for elderly drivers to adopt appropriate driving strategies commensurate with their current driving competence. © 2014 Japan Geriatrics Society.

Development and Packaging of Microsystems Using Foundry Services

DTIC Science & Technology

1998-06-01

DEVELOPMENT AND PACKAGING OF MICROSYSTEMS USING FOUNDRY SERVICES Jeffrey T. Butler, BSEE, MSEE Captain, USAF Approved: Paul H . Ostdiek, PhD, Lt...structural polysilicon layers. CMOS Device Area Micromechanical Device Area arsenic-daped epitaxial layer >J1M* ’ MM t° H 0J n-type ailioon...Ö ♦ * ♦ m B 1 —i ft H 035 0.045 0.055 0.065 0.075 Power Applied to Driver (W) (b) Figure 4-4. (a) Driver output loading

Amplified Arctic warming by phytoplankton under greenhouse warming.

PubMed

Park, Jong-Yeon; Kug, Jong-Seong; Bader, Jürgen; Rolph, Rebecca; Kwon, Minho

2015-05-12

Phytoplankton have attracted increasing attention in climate science due to their impacts on climate systems. A new generation of climate models can now provide estimates of future climate change, considering the biological feedbacks through the development of the coupled physical-ecosystem model. Here we present the geophysical impact of phytoplankton, which is often overlooked in future climate projections. A suite of future warming experiments using a fully coupled ocean-atmosphere model that interacts with a marine ecosystem model reveals that the future phytoplankton change influenced by greenhouse warming can amplify Arctic surface warming considerably. The warming-induced sea ice melting and the corresponding increase in shortwave radiation penetrating into the ocean both result in a longer phytoplankton growing season in the Arctic. In turn, the increase in Arctic phytoplankton warms the ocean surface layer through direct biological heating, triggering additional positive feedbacks in the Arctic, and consequently intensifying the Arctic warming further. Our results establish the presence of marine phytoplankton as an important potential driver of the future Arctic climate changes.

Molecular control of steady-state dendritic cell maturation and immune homeostasis.

PubMed

Hammer, Gianna Elena; Ma, Averil

2013-01-01

Dendritic cells (DCs) are specialized sentinels responsible for coordinating adaptive immunity. This function is dependent upon coupled sensitivity to environmental signs of inflammation and infection to cellular maturation-the programmed alteration of DC phenotype and function to enhance immune cell activation. Although DCs are thus well equipped to respond to pathogens, maturation triggers are not unique to infection. Given that immune cells are exquisitely sensitive to the biological functions of DCs, we now appreciate that multiple layers of suppression are required to restrict the environmental sensitivity, cellular maturation, and even life span of DCs to prevent aberrant immune activation during the steady state. At the same time, steady-state DCs are not quiescent but rather perform key functions that support homeostasis of numerous cell types. Here we review these functions and molecular mechanisms of suppression that control steady-state DC maturation. Corruption of these steady-state operatives has diverse immunological consequences and pinpoints DCs as potent drivers of autoimmune and inflammatory disease.

Amplified Arctic warming by phytoplankton under greenhouse warming

PubMed Central

Park, Jong-Yeon; Kug, Jong-Seong; Bader, Jürgen; Rolph, Rebecca; Kwon, Minho

2015-01-01

Phytoplankton have attracted increasing attention in climate science due to their impacts on climate systems. A new generation of climate models can now provide estimates of future climate change, considering the biological feedbacks through the development of the coupled physical–ecosystem model. Here we present the geophysical impact of phytoplankton, which is often overlooked in future climate projections. A suite of future warming experiments using a fully coupled ocean−atmosphere model that interacts with a marine ecosystem model reveals that the future phytoplankton change influenced by greenhouse warming can amplify Arctic surface warming considerably. The warming-induced sea ice melting and the corresponding increase in shortwave radiation penetrating into the ocean both result in a longer phytoplankton growing season in the Arctic. In turn, the increase in Arctic phytoplankton warms the ocean surface layer through direct biological heating, triggering additional positive feedbacks in the Arctic, and consequently intensifying the Arctic warming further. Our results establish the presence of marine phytoplankton as an important potential driver of the future Arctic climate changes. PMID:25902494

Seepage from an arctic shallow marine gas hydrate reservoir is insensitive to momentary ocean warming

PubMed Central

Hong, Wei-Li; Torres, Marta E.; Carroll, JoLynn; Crémière, Antoine; Panieri, Giuliana; Yao, Haoyi; Serov, Pavel

2017-01-01

Arctic gas hydrate reservoirs located in shallow water and proximal to the sediment-water interface are thought to be sensitive to bottom water warming that may trigger gas hydrate dissociation and the release of methane. Here, we evaluate bottom water temperature as a potential driver for hydrate dissociation and methane release from a recently discovered, gas-hydrate-bearing system south of Spitsbergen (Storfjordrenna, ∼380 m water depth). Modelling of the non-steady-state porewater profiles and observations of distinct layers of methane-derived authigenic carbonate nodules in the sediments indicate centurial to millennial methane emissions in the region. Results of temperature modelling suggest limited impact of short-term warming on gas hydrates deeper than a few metres in the sediments. We conclude that the ongoing and past methane emission episodes at the investigated sites are likely due to the episodic ventilation of deep reservoirs rather than warming-induced gas hydrate dissociation in this shallow water seep site. PMID:28589962

Seepage from an arctic shallow marine gas hydrate reservoir is insensitive to momentary ocean warming

DOE PAGES

Hong, Wei-Li; Torres, Marta E.; Carroll, JoLynn; ...

2017-06-07

Arctic gas hydrate reservoirs located in shallow water and proximal to the sediment-water interface are thought to be sensitive to bottom water warming that may trigger gas hydrate dissociation and the release of methane. Here, we evaluate bottom water temperature as a potential driver for hydrate dissociation and methane release from a recently discovered, gas-hydrate-bearing system south of Spitsbergen (Storfjordrenna, ~380m water depth). Modelling of the non-steady-state porewater profiles and observations of distinct layers of methane-derived authigenic carbonate nodules in the sediments indicate centurial to millennial methane emissions in the region. The results of temperature modelling suggest limited impact ofmore » short-term warming on gas hydrates deeper than a few metres in the sediments. We conclude that the ongoing and past methane emission episodes at the investigated sites are likely due to the episodic ventilation of deep reservoirs rather than warming-induced gas hydrate dissociation in this shallow water seep site.« less

Seepage from an arctic shallow marine gas hydrate reservoir is insensitive to momentary ocean warming.

PubMed

Hong, Wei-Li; Torres, Marta E; Carroll, JoLynn; Crémière, Antoine; Panieri, Giuliana; Yao, Haoyi; Serov, Pavel

2017-06-07

Arctic gas hydrate reservoirs located in shallow water and proximal to the sediment-water interface are thought to be sensitive to bottom water warming that may trigger gas hydrate dissociation and the release of methane. Here, we evaluate bottom water temperature as a potential driver for hydrate dissociation and methane release from a recently discovered, gas-hydrate-bearing system south of Spitsbergen (Storfjordrenna, ∼380 m water depth). Modelling of the non-steady-state porewater profiles and observations of distinct layers of methane-derived authigenic carbonate nodules in the sediments indicate centurial to millennial methane emissions in the region. Results of temperature modelling suggest limited impact of short-term warming on gas hydrates deeper than a few metres in the sediments. We conclude that the ongoing and past methane emission episodes at the investigated sites are likely due to the episodic ventilation of deep reservoirs rather than warming-induced gas hydrate dissociation in this shallow water seep site.

Seepage from an arctic shallow marine gas hydrate reservoir is insensitive to momentary ocean warming

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hong, Wei-Li; Torres, Marta E.; Carroll, JoLynn

Arctic gas hydrate reservoirs located in shallow water and proximal to the sediment-water interface are thought to be sensitive to bottom water warming that may trigger gas hydrate dissociation and the release of methane. Here, we evaluate bottom water temperature as a potential driver for hydrate dissociation and methane release from a recently discovered, gas-hydrate-bearing system south of Spitsbergen (Storfjordrenna, ~380m water depth). Modelling of the non-steady-state porewater profiles and observations of distinct layers of methane-derived authigenic carbonate nodules in the sediments indicate centurial to millennial methane emissions in the region. The results of temperature modelling suggest limited impact ofmore » short-term warming on gas hydrates deeper than a few metres in the sediments. We conclude that the ongoing and past methane emission episodes at the investigated sites are likely due to the episodic ventilation of deep reservoirs rather than warming-induced gas hydrate dissociation in this shallow water seep site.« less

Perception and biodynamics in unalerted precrash response.

PubMed

McGehee, Daniel V; Carsten, Oliver M J

2010-01-01

This research seeks to better understand unalerted driver response just prior to a serious vehicle crash. Few studies have been able to view a crash from the inside-with a camera focused on the driver and occupants. Four studies are examined: 1) a high-fidelity simulator study with an unalerted intersection incursion crash among 107 drivers; 2) four crashes from the Virginia Tech Transportation Institute (VTTI) 100 car study; 3) 58 crashes from vehicles equipped with an event triggered video recorder; and 4) a custom-designed high-fidelity simulator experiment that examined unalerted driver response to a head-on crash with a heavy truck. Analyses concentrate on decomposing driver perception, action, facial and postural changes with a focus on describing the neurophysiologic mechanisms designed to respond to danger. Results indicate that drivers involved in severe crashes generally have preview that an impact is about to occur. They respond first with vehicle control inputs (accelerator pedal release) along with facial state changes and withdrawal of the head back towards the head restraint. These responses frequently occur almost simultaneously, providing safety system designers with a number of reliable driver performance measures to monitor. Understanding such mechanisms may assist future advanced driver assistance systems (ADAS), advanced restraints, model development of advanced anthropomorphic test dummies (ATDs), injury prediction and the integration of active and passive safety systems.

Applications of a new mass-driver concept

NASA Technical Reports Server (NTRS)

Oneill, G. K.

1981-01-01

A description of the operating principles and requirements of a novel mass-driver concept is presented. The design obtains acceleration of payload bucket coils by means of transverse focussing from strong, off-axis restoring forces that are produced by drive coils operating in a 'pull-only' mode. The concept offers the unprecedented possibility of operating high-performance mass-drivers entirely within the limitations of existing commercial switching devices, such as silicon-controlled rectifiers, spark gaps, vacuum-triggered arcs or vacuum mechanical switches. Representative applications of the concept described are: (1) a large-diameter magnetic lunar launcher for payloads having autonomous maneuvering; (2) an intermediate-diameter launcher with long operational life; and (3) a reaction engine for orbit transfer of large, massive objects.

Using event-triggered naturalistic data to examine the prevalence of teen driver distractions in rear-end crashes.

PubMed

Carney, Cher; Harland, Karisa K; McGehee, Daniel V

2016-06-01

While teen driver distraction is cited as a leading cause of crashes, especially rear-end crashes, little information is available regarding its true prevalence. The majority of distraction studies rely on data derived from police reports, which provide limited information regarding driver distraction. This study examined over 400 teen driver rear-end crashes captured by in-vehicle event recorders. A secondary data analysis was conducted, paying specific attention to driver behaviors, eyes-off-road time, and response times to lead-vehicle braking. Among teens in moderate to severe rear-end crashes, over 75% of drivers were observed engaging in a potentially distracting behavior. The most frequently seen driver behaviors were cell phone use, attending to a location outside the vehicle, and attending to passengers. Drivers using a cell phone had a significantly longer response time than drivers not engaged in any behaviors, while those attending to passengers did not. Additionally, in about 50% of the rear-end crashes where the driver was operating/looking at a phone (e.g., texting), the driver showed no driver response (i.e., braking or steering input) before impact, compared to 10% of crashes where the driver was attending to a passenger. The high frequency of attending to passengers and use of a cell phone leading up to a crash, compounded with the associated risks, underlines the importance of continued investigation in these areas. Parents and teens must be educated regarding the frequency of and the potential effects of distractions. Additional enforcement may be necessary if Graduated Driver Licensing (GDL) programs are to be effective. Systems that alert distracted teens could also be especially helpful in reducing rear-end collisions. Copyright © 2016 Elsevier Ltd and National Safety Council. All rights reserved.

Rootkit Detection Using a Cross-View Clean Boot Method

DTIC Science & Technology

2013-03-01

FindNextFile: [2] Kernel32.dll 4. SSDTHooks r -- ... CALL NtQueryDirectoryFile 5. Code Patch ing - 6. Layered Driver 4 NtQueryDirectoryFile : 7...NTFS Driver 0 Volume Manger Disk Driver [2] I. Disk Driver r ! J IAT hooks take advantage of function calls in applications [13]. When an...f36e923898161fa7be50810288e2f48a 61 Appendix D: Windows Source Code Windows Batch File @echo o f f py thon walk . py pause shutdown − r − t 0 Walk.py in

Investigating the effectiveness of using Bluetooth low-energy technology to trigger in-vehicle messages in work zones : final report.

DOT National Transportation Integrated Search

2016-12-01

In order to reduce risky behavior around workzones, this project examines the effectiveness of using in-vehicle : messages to heighten drivers awareness of safety-critical and pertinent workzone information. : This investigation centers around an ...

Implement an adjustable delay time digital trigger for an NI data acquisition card in a high-speed demodulation system

NASA Astrophysics Data System (ADS)

Zhang, Hongtao; Fan, Lingling; Wang, Pengfei; Park, Seong-Wook

2012-06-01

A National Instruments (NI) DAQ card PCI 5105 is installed in a high-speed demodulation system based on Fiber Fabry-Pérot Tunable Filter. The instability of the spectra of Fiber Bragg Grating sensors caused by intrinsic drifts of FFP-TF needs an appropriate, flexible trigger. However, the driver of the DAQ card in the current development environment does not provide the functions of analog trigger but digital trigger type. Moreover, the high level of the trigger signal from the tuning voltage of FFP-TF is larger than the maximum input overload voltage of PCI 5105 card. To resolve this incompatibility, a novel converter to change an analog trigger signal into a digital trigger signal has been reported previously. However, the obvious delay time between input and output signals limits the function of demodulation system. Accordingly, we report an improved low-cost, small-size converter with an adjustable delay time. This new scheme can decline the delay time to or close to zero when the frequency of trigger signal is less than 3,000 Hz. This method might be employed to resolve similar problems or to be applied in semiconductor integrated circuits.

Methods for batch fabrication of cold cathode vacuum switch tubes

DOEpatents

Walker, Charles A [Albuquerque, NM; Trowbridge, Frank R [Albuquerque, NM

2011-05-10

Methods are disclosed for batch fabrication of vacuum switch tubes that reduce manufacturing costs and improve tube to tube uniformity. The disclosed methods comprise creating a stacked assembly of layers containing a plurality of adjacently spaced switch tube sub-assemblies aligned and registered through common layers. The layers include trigger electrode layer, cathode layer including a metallic support/contact with graphite cathode inserts, trigger probe sub-assembly layer, ceramic (e.g. tube body) insulator layer, and metallic anode sub-assembly layer. Braze alloy layers are incorporated into the stacked assembly of layers, and can include active metal braze alloys or direct braze alloys, to eliminate costs associated with traditional metallization of the ceramic insulator layers. The entire stacked assembly is then heated to braze/join/bond the stack-up into a cohesive body, after which individual switch tubes are singulated by methods such as sawing. The inventive methods provide for simultaneously fabricating a plurality of devices as opposed to traditional methods that rely on skilled craftsman to essentially hand build individual devices.

Perception and Biodynamics in Unalerted Precrash Response

PubMed Central

McGehee, Daniel V.; Carsten, Oliver M.J.

2010-01-01

This research seeks to better understand unalerted driver response just prior to a serious vehicle crash. Few studies have been able to view a crash from the inside—with a camera focused on the driver and occupants. Four studies are examined: 1) a high-fidelity simulator study with an unalerted intersection incursion crash among 107 drivers; 2) four crashes from the Virginia Tech Transportation Institute (VTTI) 100 car study; 3) 58 crashes from vehicles equipped with an event triggered video recorder; and 4) a custom-designed high-fidelity simulator experiment that examined unalerted driver response to a head-on crash with a heavy truck. Analyses concentrate on decomposing driver perception, action, facial and postural changes with a focus on describing the neurophysiologic mechanisms designed to respond to danger. Results indicate that drivers involved in severe crashes generally have preview that an impact is about to occur. They respond first with vehicle control inputs (accelerator pedal release) along with facial state changes and withdrawal of the head back towards the head restraint. These responses frequently occur almost simultaneously, providing safety system designers with a number of reliable driver performance measures to monitor. Understanding such mechanisms may assist future advanced driver assistance systems (ADAS), advanced restraints, model development of advanced anthropomorphic test dummies (ATDs), injury prediction and the integration of active and passive safety systems. PMID:21050614

Thin layer composite unimorph ferroelectric driver and sensor

NASA Technical Reports Server (NTRS)

Hellbaum, Richard F. (Inventor); Bryant, Robert G. (Inventor); Fox, Robert L. (Inventor); Jalink, Jr., Antony (Inventor); Rohrbach, Wayne W. (Inventor); Simpson, Joycelyn O. (Inventor)

2004-01-01

A method for forming ferroelectric wafers is provided. A prestress layer is placed on the desired mold. A ferroelectric wafer is placed on top of the prestress layer. The layers are heated and then cooled, causing the ferroelectric wafer to become prestressed. The prestress layer may include reinforcing material and the ferroelectric wafer may include electrodes or electrode layers may be placed on either side of the ferroelectric layer. Wafers produced using this method have greatly improved output motion.

Thin Layer Composite Unimorph Ferroelectric Driver and Sensor

NASA Technical Reports Server (NTRS)

Helbaum, Richard F. (Inventor); Bryant, Robert G. (Inventor); Fox, Robert L. (Inventor); Jalink, Antony, Jr. (Inventor); Rohrbach, Wayne W. (Inventor); Simpson, Joycelyn O. (Inventor)

1995-01-01

A method for forming ferroelectric wafers is provided. A prestress layer is placed on the desired mold. A ferroelectric wafer is placed on top of the prestress layer. The layers are heated and then cooled, causing the ferroelectric wafer to become prestressed. The prestress layer may include reinforcing material and the ferroelectric wafer may include electrodes or electrode layers may be placed on either side of the ferroelectric layer. Wafers produced using this method have greatly improved output motion.

A Cross-Layer User Centric Vertical Handover Decision Approach Based on MIH Local Triggers

NASA Astrophysics Data System (ADS)

Rehan, Maaz; Yousaf, Muhammad; Qayyum, Amir; Malik, Shahzad

Vertical handover decision algorithm that is based on user preferences and coupled with Media Independent Handover (MIH) local triggers have not been explored much in the literature. We have developed a comprehensive cross-layer solution, called Vertical Handover Decision (VHOD) approach, which consists of three parts viz. mechanism for collecting and storing user preferences, Vertical Handover Decision (VHOD) algorithm and the MIH Function (MIHF). MIHF triggers the VHOD algorithm which operates on user preferences to issue handover commands to mobility management protocol. VHOD algorithm is an MIH User and therefore needs to subscribe events and configure thresholds for receiving triggers from MIHF. In this regard, we have performed experiments in WLAN to suggest thresholds for Link Going Down trigger. We have also critically evaluated the handover decision process, proposed Just-in-time interface activation technique, compared our proposed approach with prominent user centric approaches and analyzed our approach from different aspects.

Root assays to study pattern-triggered immunity in plant-nematode interactions

USDA-ARS?s Scientific Manuscript database

Plants employ extracellular immune receptors to perceive conserved pathogen-associated molecular patterns (PAMPs), triggering the first layer of defense known as pattern-triggered immunity (PTI). The understanding of PTI is mainly based on the studies focusing on leaves. Plants are vulnerable to att...

Teaching as a Career Choice: Triggers and Drivers

ERIC Educational Resources Information Center

Low, Ee Ling; Ng, Pak Tee; Hui, Chenri; Cai, Li

2017-01-01

Why people are drawn to teaching has been a focal research area. However, previous studies seem to centre on the traditional conceptualisations of intrinsic, altruistic, and extrinsic motivations as well as some other similar categorisations. This study attempts to discuss the issue from a different conceptual stance, proposing a distinction…

High enthalpy hypersonic boundary layer flow

NASA Technical Reports Server (NTRS)

Yanow, G.

1972-01-01

A theoretical and experimental study of an ionizing laminar boundary layer formed by a very high enthalpy flow (in excess of 12 eV per atom or 7000 cal/gm) with allowance for the presence of helium driver gas is described. The theoretical investigation has shown that the use of variable transport properties and their respective derivatives is very important in the solution of equilibrium boundary layer equations of high enthalpy flow. The effect of low level helium contamination on the surface heat transfer rate is minimal. The variation of ionization is much smaller in a chemically frozen boundary layer solution than in an equilibrium boundary layer calculation and consequently, the variation of the transport properties in the case of the former was not essential in the integration. The experiments have been conducted in a free piston shock tunnel, and a detailed study of its nozzle operation, including the effects of low levels of helium driver gas contamination has been made. Neither the extreme solutions of an equilibrium nor of a frozen boundary layer will adequately predict surface heat transfer rate in very high enthalpy flows.

The reaction times of drivers aged 20 to 80 during a divided attention driving.

PubMed

Svetina, Matija

2016-11-16

Many studies addressing age-related changes in driving performance focus on comparing young vs. older drivers, which might lead to the biased conclusion that driving performance decreases only after the age of 65. The main aim of the study was to show that changes in driving performance are progressive throughout the adult years. A sample of 351 drivers aged 20 to 80 was assessed for their reaction times while driving between road cones. The drivers were exposed to 2 conditions varying according to task complexity. In single task conditions, the drivers performed a full stopping maneuver at a given signal; in dual task conditions, the drivers were distracted before the signal for stopping maneuver was triggered. Reaction times were compared across conditions and age groups. The results showed that both reaction times and variability of driving performance increased progressively between the ages of 20 and 80. The increase in both reaction times and variability was greater in the complex task condition. The high-performing quarter of elderly drivers performed equally well or better than younger drivers did. The data clearly supported the claim that driving performance changes steadily across age groups: both mean reaction time and interindividual variability progressively increase with age. In addition, a significant group of older drivers was identified who did not show the expected age-related decrease in performance. The findings have important implications, suggesting that in relation to driving, aging is a progressive phenomenon and may lead to variety of driving performance; age-related studies of driving performance should put more emphasis on investigating changes across the whole driver age range rather than only comparing younger and older drivers.

Carpet: Adaptive Mesh Refinement for the Cactus Framework

NASA Astrophysics Data System (ADS)

Schnetter, Erik; Hawley, Scott; Hawke, Ian

2016-11-01

Carpet is an adaptive mesh refinement and multi-patch driver for the Cactus Framework (ascl:1102.013). Cactus is a software framework for solving time-dependent partial differential equations on block-structured grids, and Carpet acts as driver layer providing adaptive mesh refinement, multi-patch capability, as well as parallelization and efficient I/O.

Intercomparison of Air-Sea Fluxes in the Bay of Bengal

NASA Astrophysics Data System (ADS)

Buckley, J.; Weller, R. A.; Farrar, J. T.; Tandon, A.

2016-02-01

Heat and momentum exchange between the air and sea in the Bay of Bengal is an important driver of atmospheric convection during the Asian Monsoon. Warm sea surface temperatures resulting from salinity stratified shallow mixed layers trigger widespread showers and thunderstorms. In this study, we compare atmospheric reanalysis flux products to air-sea flux values calculated from shipboard observations from four cruises and an air-sea flux mooring in the Bay of Bengal as part of the Air-Sea Interactions in the Northern Indian Ocean (ASIRI) experiment. Comparisons with months of mooring data show that most long timescale reanalysis error arises from the overestimation of longwave and shortwave radiation. Ship observations and select data from the air-sea flux mooring reveals significant errors on shorter timescales (2-4 weeks) which are greatly influenced by errors in shortwave radiation and latent and sensible heat. During these shorter periods, the reanalyses fail to properly show sharp decreases in air temperature, humidity, and shortwave radiation associated with mesoscale convective systems. Simulations with the Price-Weller-Pinkel (PWP) model show upper ocean mixing and deepening mixed layers during these events that effect the long term upper ocean stratification. Mesoscale convective systems associated with cloudy skies and cold and dry air can reduce net heat into the ocean for minutes to a few days, significantly effecting air-sea heat transfer, upper ocean stratification, and ocean surface temperature and salinity.

A Scalable Data Access Layer to Manage Structured Heterogeneous Biomedical Data.

PubMed

Delussu, Giovanni; Lianas, Luca; Frexia, Francesca; Zanetti, Gianluigi

2016-01-01

This work presents a scalable data access layer, called PyEHR, designed to support the implementation of data management systems for secondary use of structured heterogeneous biomedical and clinical data. PyEHR adopts the openEHR's formalisms to guarantee the decoupling of data descriptions from implementation details and exploits structure indexing to accelerate searches. Data persistence is guaranteed by a driver layer with a common driver interface. Interfaces for two NoSQL Database Management Systems are already implemented: MongoDB and Elasticsearch. We evaluated the scalability of PyEHR experimentally through two types of tests, called "Constant Load" and "Constant Number of Records", with queries of increasing complexity on synthetic datasets of ten million records each, containing very complex openEHR archetype structures, distributed on up to ten computing nodes.

Drowsy driver mobile application: Development of a novel scleral-area detection method.

PubMed

Mohammad, Faisal; Mahadas, Kausalendra; Hung, George K

2017-10-01

A reliable and practical app for mobile devices was developed to detect driver drowsiness. It consisted of two main components: a Haar cascade classifier, provided by a computer vision framework called OpenCV, for face/eye detection; and a dedicated JAVA software code for image processing that was applied over a masked region circumscribing the eye. A binary threshold was performed over the masked region to provide a quantitative measure of the number of white pixels in the sclera, which represented the state of eye opening. A continuously low white-pixel count would indicate drowsiness, thereby triggering an alarm to alert the driver. This system was successfully implemented on: (1) a static face image, (2) two subjects under laboratory conditions, and (3) a subject in a vehicle environment. Copyright © 2017 Elsevier Ltd. All rights reserved.

Designing high speed diagnostics

NASA Astrophysics Data System (ADS)

Veliz Carrillo, Gerardo; Martinez, Adam; Mula, Swathi; Prestridge, Kathy; Extreme Fluids Team Team

2017-11-01

Timing and firing for shock-driven flows is complex because of jitter in the shock tube mechanical drivers. Consequently, experiments require dynamic triggering of diagnostics from pressure transducers. We explain the design process and criteria for setting up re-shock experiments at the Los Alamos Vertical Shock Tube facility, and the requirements for particle image velocimetry and planar laser induced fluorescence measurements necessary for calculating Richtmeyer-Meshkov variable density turbulent statistics. Dynamic triggering of diagnostics allows for further investigation of the development of the Richtemeyer-Meshkov instability at both initial shock and re-shock. Thanks to the Los Alamos National Laboratory for funding our project.

Driver drowsiness detection using ANN image processing

NASA Astrophysics Data System (ADS)

Vesselenyi, T.; Moca, S.; Rus, A.; Mitran, T.; Tătaru, B.

2017-10-01

The paper presents a study regarding the possibility to develop a drowsiness detection system for car drivers based on three types of methods: EEG and EOG signal processing and driver image analysis. In previous works the authors have described the researches on the first two methods. In this paper the authors have studied the possibility to detect the drowsy or alert state of the driver based on the images taken during driving and by analyzing the state of the driver’s eyes: opened, half-opened and closed. For this purpose two kinds of artificial neural networks were employed: a 1 hidden layer network and an autoencoder network.

Spying or steering? Views of parents of young novice drivers on the use and ethics of driver-monitoring technologies.

PubMed

Guttman, Nurit; Lotan, Tsippy

2011-01-01

In-vehicle technologies that document driving practices have the potential to enhance the driving safety of young drivers, but their installation depends largely on their parents' willingness and raises ethical dilemmas. This study investigated, using closed and open-ended questions, the views of 906 parents of young drivers in Israel regarding their willingness to install such a technology, and their conceptions of social norms and ethical issues associated with the technology and of factors that would encourage or discourage parents to adopt it. Most believed parents should feel morally obligated to install it. When cost was not a consideration, most said they would, and believed other parents would be willing to install the technology. Fewer (about half) expressed willingness to install it after being told about its estimated cost. Monetary cost was rated as a barrier to install it by about half. Environmental considerations were viewed as an incentive. Parents who supported the installation believed it would serve as a trigger for parent-young driver communication but those who did not thought it would erode trust in the parent-young driver relationship. Most said parents should have access to the monitoring data. Policy implications regarding issues of privacy and resources for parents are discussed. Copyright © 2010 Elsevier Ltd. All rights reserved.

Inner layer-embedded contact lenses for pH-triggered controlled ocular drug delivery.

PubMed

Zhu, Qiang; Liu, Chang; Sun, Zheng; Zhang, Xiaofei; Liang, Ning; Mao, Shirui

2018-07-01

Contact lenses (CLs) are ideally suited for controlled ocular drug delivery, but are limited by short release duration, poor storage stability and low drug loading. In this study, we present a novel inner layer-embedded contact lens capable of pH-triggered extended ocular drug delivery with good storage stability. Blend film of ethyl cellulose and Eudragit S100 was used as the inner layer, while pHEMA hydrogel was used as outer layer to fabricate inner layer-embedded contact lens. Using diclofenac sodium(DS) as a drug model, influence of polymer ratio in the blend film, EC viscosity, drug/polymer ratio, inner layer thickness and outlayer thickness of pHEMA hydrogel on drug release behavior was studied and optimized for daily use. The pH-triggered drug eluting pattern enables the inner layer-embedded contact lens being stored in phosphate buffer solution pH 6.8 with ignorable drug loss and negligible changes in drug release pattern. In vivo pharmacokinetic study in rabbits showed sustained drug release for over 24 h in tear fluid, indicating significant improvement in drug corneal residence time. A level A IVIVC was established between in vitro drug release and in vivo drug concentration in tear fluid. In conclusion, this inner layer embedded contact lens design could be used as a platform for extended ocular drug delivery with translational potential for both anterior and posterior ocular diseases therapy. Copyright © 2018 Elsevier B.V. All rights reserved.

Microtopographic Evidence of Hillslope Susceptibility to Active Layer Detachments and Rapid Soil Erosion in Permafrost-dominated Watersheds

NASA Astrophysics Data System (ADS)

Rowland, J. C.; Shelef, E.; Sutfin, N. A.; Piliouras, A.; Andresen, C. G.; Wilson, C. J.

2017-12-01

Movement and storage rates of soil and carbon along permafrost-dominated hillslopes may vary dramatically from long-term steady creeping, at centimeters per year, to rapid gullying, land sliding, and active layer detachments of meter to decimeter sized portions of hillslopes. The rate and drivers of hillslope soil processes may have strong feedbacks on microtopography and hydrology that in turn strongly influence vegetation dynamics and biogeochemistry within watersheds. We observed evidence of both steady soil creep and more catastrophic soil erosion processes occurring across three small watersheds in the southern Seward Peninsula, AK. In these watersheds, we inferred active soil creep processes from the occurrence of solifluction lobes with partially buried shrubs and tilted survey benchmarks on slopes lacking lobes. More dramatic and rapid erosion of soils was evidenced by active layer detachments, extensional cracks in the tundra vegetation, gullying, and both small- and large-scale soil failure scarps. The margins and heads of valley hollows exhibited failure scars up to 4m in height. The spatial distribution of actively eroding areas suggests that some portions of hilllslopes may be more susceptible to rapid erosion. Coring of hillslope soils suggests a possible association between more actively eroding areas and the presence of an ice-rich layer (> 50%) at depths of approximately 90 cm down to the inferred top of bedrock at depths at 170 to 200 cm. We observed that the surface of these hillslope regions appears to have greater microtopographic roughness with a more chaotic and "lumpy" surface than portions of the hillslope were no massive ice layers were encountered. We hypothesize that the extensional cracking and chaotic surface roughness may arise from small-scale soil failures triggered when the seasonal thaw depth intersects the ice-rich layer. It may be possible to identify hillslope regions underlain by ice-rich layers with greater susceptibility for localized erosion and deformation based on a quantitative characterization of the hillslope microtopography. Using drone-based LiDAR topographic data to be acquired in late summer of 2017, we will quantitatively explore the relationship between microtopography and hillslope ice-content.

Wildland fire emissions, carbon, and climate: Science overview and knowledge needs

Treesearch

William T. Sommers; Rachel A. Loehman; Colin C. Hardy

2014-01-01

Wildland fires have influenced the global carbon cycle for 420 million years of Earth history, interacting with climate to define vegetation characteristics and distributions, trigger abrupt ecosystem shifts, and move carbon among terrestrial and atmospheric pools. Carbon dioxide (CO2) is the dominant driver of ongoing climate change and the principal emissions...

Assessing the impact of emerging forest disease on wildfire using Landsat and KOMPSAT-2 data

Treesearch

Gang Chen; Yinan He; Angela De Santis; Guosheng Li; Richard Cobb; Ross K. Meentemeyer

2017-01-01

Environmental disturbance regimes are more frequently being altered by historically novel events and disturbance interactions, which may trigger reorganizations of new ecosystem states and processes. Here we examine synergies between emerging forest disease and wildfire to determine whether disease outbreak changes environmental drivers of burn severity using sudden...

Herbivore impacts to the moss layer determine tundra ecosystem response to grazing and warming.

PubMed

Gornall, Jemma L; Woodin, Sarah J; Jónsdóttir, Ingibjörg S; Van der Wal, Rene

2009-10-01

Herbivory and climate are key environmental drivers, shaping ecosystems at high latitudes. Here, we focus on how these two drivers act in concert, influencing the high arctic tundra. We aim to investigate mechanisms through which herbivory by geese influences vegetation and soil processes in tundra ecosystems under ambient and warmed conditions. To achieve this, two grazing treatments, clipping plus faecal additions and moss removal, were implemented in conjunction with passive warming. Our key finding was that, in many cases, the tundra ecosystem response was determined by treatment impacts on the moss layer. Moss removal reduced the remaining moss layer depth by 30% and increased peak grass biomass by 27%. These impacts were probably due to observed higher soil temperatures and decomposition rates associated with moss removal. The positive impact of moss removal on grass biomass was even greater with warming, further supporting this conclusion. In contrast, moss removal reduced dwarf shrub biomass possibly resulting from increased exposure to desiccating winds. An intact moss layer buffered the soil to increased air temperature and as a result there was no response of vascular plant productivity to warming over the course of this study. In fact, moss removal impacts on soil temperature were nearly double those of warming, suggesting that the moss layer is a key component in controlling soil conditions. The moss layer also absorbed nutrients from faeces, promoting moss growth. We conclude that both herbivory and warming influence this high arctic ecosystem but that herbivory is the stronger driver of the two. Disturbance to the moss layer resulted in a shift towards a more grass-dominated system with less abundant mosses and shrubs, a trend that was further enhanced by warming. Thus herbivore impacts to the moss layer are key to understanding arctic ecosystem response to grazing and warming.

Self-defensive antibiotic-loaded layer-by-layer coatings: Imaging of localized bacterial acidification and pH-triggering of antibiotic release.

PubMed

Albright, Victoria; Zhuk, Iryna; Wang, Yuhao; Selin, Victor; van de Belt-Gritter, Betsy; Busscher, Henk J; van der Mei, Henny C; Sukhishvili, Svetlana A

2017-10-01

Self-defensive antibiotic-loaded coatings have shown promise in inhibiting growth of pathogenic bacteria adhering to biomaterial implants and devices, but direct proof that their antibacterial release is triggered by bacterially-induced acidification of the immediate environment under buffered conditions remained elusive. Here, we demonstrate that Staphylococcus aureus and Escherichia coli adhering to such coatings generate highly localized acidification, even in buffered conditions, to activate pH-triggered, self-defensive antibiotic release. To this end, we utilized chemically crosslinked layer-by-layer hydrogel coatings of poly(methacrylic acid) with a covalently attached pH-sensitive SNARF-1 fluorescent label for imaging, and unlabeled-antibiotic (gentamicin or polymyxin B) loaded coatings for antibacterial studies. Local acidification of the coatings induced by S. aureus and E. coli adhering to the coatings was demonstrated by confocal-laser-scanning-microscopy via wavelength-resolved imaging. pH-triggered antibiotic release under static, small volume conditions yielded high bacterial killing efficiencies for S. aureus and E. coli. Gentamicin-loaded films retained their antibacterial activity against S. aureus under fluid flow in buffered conditions. Antibacterial activity increased with the number of polymer layers in the films. Altogether, pH-triggered, self-defensive antibiotic-loaded coatings become activated by highly localized acidification in the immediate environment of an adhering bacterium, offering potential for clinical application with minimized side-effects. Polymeric coatings were created that are able to uptake and selectively release antibiotics upon stimulus by adhering bacteria in order to understand the fundamental mechanisms behind pH-triggered antibiotic release as a potential way to prevent biomaterial-associated infections. Through fluorescent imaging studies, this work importantly shows that adhering bacteria produce highly localized pH changes even in buffer. Accordingly such coatings only demonstrate antibacterial activity by antibiotic release in the presence of adhering bacteria. This is clinically important, because ad libitum releasing antibiotic coatings usually show a burst release and have often lost their antibiotic content when bacteria adhere. Copyright © 2017 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

A Scalable Data Access Layer to Manage Structured Heterogeneous Biomedical Data

PubMed Central

Lianas, Luca; Frexia, Francesca; Zanetti, Gianluigi

2016-01-01

This work presents a scalable data access layer, called PyEHR, designed to support the implementation of data management systems for secondary use of structured heterogeneous biomedical and clinical data. PyEHR adopts the openEHR’s formalisms to guarantee the decoupling of data descriptions from implementation details and exploits structure indexing to accelerate searches. Data persistence is guaranteed by a driver layer with a common driver interface. Interfaces for two NoSQL Database Management Systems are already implemented: MongoDB and Elasticsearch. We evaluated the scalability of PyEHR experimentally through two types of tests, called “Constant Load” and “Constant Number of Records”, with queries of increasing complexity on synthetic datasets of ten million records each, containing very complex openEHR archetype structures, distributed on up to ten computing nodes. PMID:27936191

Drivers of land use/land cover changes in Munessa-Shashemene landscape of the south-central highlands of Ethiopia.

PubMed

Kindu, Mengistie; Schneider, Thomas; Teketay, Demel; Knoke, Thomas

2015-07-01

Understanding drivers of changes in land use/land cover (LULC) is essential for modeling future dynamics or development of management strategies to ameliorate or prevent further decline of natural resources. In this study, an attempt has been made to identify the main drivers behind the LULC changes that had occurred in the past four decades in Munessa-Shashemene landscape of the south-central highlands of Ethiopia. The datasets required for the study were generated through both primary and secondary sources. Combination of techniques, including descriptive statistics, GIS-based processing, and regression analyses were employed for data analyses. Changes triggered by the interplay of more than 12 drivers were identified related to social, economic, environmental, policy/institutional, and technological factors. Specifically, population growth, expansion of cultivated lands and settlements, livestock ranching, cutting of woody species for fuelwood, and charcoal making were the top six important drivers of LULC change as viewed by the local people and confirmed by quantitative analyses. Differences in respondents' perceptions related to environmental (i.e., location specific) and socioeconomic determinants (e.g., age and literacy) about drivers were statically significant (P = 0.001). LULC changes were also determined by distances to major drivers (e.g., the further a pixel is from the road, the less likelihood of changes) as shown by the landscape level analyses. Further studies are suggested targeting these drivers to explore the consequences and future options and formulate intervention strategies for sustainable development in the studied landscape and elsewhere with similar geographic settings.

Regenerative braking failures in battery electric vehicles and their impact on the driver.

PubMed

Cocron, Peter; Neumann, Isabel; Kreußlein, Maria; Wanner, Daniel; Bierbach, Maxim; Krems, Josef F

2018-09-01

A unique feature of battery electric vehicles (BEV) is their regenerative braking system (RBS) to recapture kinetic energy in deceleration maneuvers. If such a system is triggered via gas pedal, most deceleration maneuvers can be executed by just using this pedal. This impacts the driving task as different deceleration strategies can be applied. Previous research has indicated that a RBS failure leading to a sudden reduced deceleration represents an adverse event for BEV drivers. In the present study, we investigated such a failure's impact on the driver's evaluation and behavior. We conducted an experiment on a closed-off test track using a modified BEV that could temporarily switch off the RBS. One half of the 44 participants in the study received information about an upcoming RBS failure whereas the other half did not. While 91% of the drivers receiving prior information noticed the RBS failure, only 48% recognized it in the "uniformed" group. In general, the failure and the perception of its occurrence influenced the driver's evaluation and behavior more than receiving prior information. Nevertheless, under the tested conditions, drivers kept control and were able to compensate for the RBS failure. As the participants drove quite simple maneuvers in our experiment, further studies are needed to validate our findings using more complex driving settings. Given that RBS failures could have severe consequences, appropriate information and warning strategies for drivers are necessary. Copyright © 2018 Elsevier Ltd. All rights reserved.

Drivers of Rift Valley fever epidemics in Madagascar

PubMed Central

Lancelot, Renaud; Béral, Marina; Rakotoharinome, Vincent Michel; Andriamandimby, Soa-Fy; Héraud, Jean-Michel; Coste, Caroline; Apolloni, Andrea; Squarzoni-Diaw, Cécile; de La Rocque, Stéphane; Wint, G. R. William; Cardinale, Eric

2017-01-01

Rift Valley fever (RVF) is a vector-borne viral disease widespread in Africa. The primary cycle involves mosquitoes and wild and domestic ruminant hosts. Humans are usually contaminated after contact with infected ruminants. As many environmental, agricultural, epidemiological, and anthropogenic factors are implicated in RVF spread, the multidisciplinary One Health approach was needed to identify the drivers of RVF epidemics in Madagascar. We examined the environmental patterns associated with these epidemics, comparing human and ruminant serological data with environmental and cattle-trade data. In contrast to East Africa, environmental drivers did not trigger the epidemics: They only modulated local Rift Valley fever virus (RVFV) transmission in ruminants. Instead, RVFV was introduced through ruminant trade and subsequent movement of cattle between trade hubs caused its long-distance spread within the country. Contact with cattle brought in from infected districts was associated with higher infection risk in slaughterhouse workers. The finding that anthropogenic rather than environmental factors are the main drivers of RVF infection in humans can be used to design better prevention and early detection in the case of RVF resurgence in the region. PMID:28096420

Drivers of Rift Valley fever epidemics in Madagascar.

PubMed

Lancelot, Renaud; Béral, Marina; Rakotoharinome, Vincent Michel; Andriamandimby, Soa-Fy; Héraud, Jean-Michel; Coste, Caroline; Apolloni, Andrea; Squarzoni-Diaw, Cécile; de La Rocque, Stéphane; Formenty, Pierre B H; Bouyer, Jérémy; Wint, G R William; Cardinale, Eric

2017-01-31

Rift Valley fever (RVF) is a vector-borne viral disease widespread in Africa. The primary cycle involves mosquitoes and wild and domestic ruminant hosts. Humans are usually contaminated after contact with infected ruminants. As many environmental, agricultural, epidemiological, and anthropogenic factors are implicated in RVF spread, the multidisciplinary One Health approach was needed to identify the drivers of RVF epidemics in Madagascar. We examined the environmental patterns associated with these epidemics, comparing human and ruminant serological data with environmental and cattle-trade data. In contrast to East Africa, environmental drivers did not trigger the epidemics: They only modulated local Rift Valley fever virus (RVFV) transmission in ruminants. Instead, RVFV was introduced through ruminant trade and subsequent movement of cattle between trade hubs caused its long-distance spread within the country. Contact with cattle brought in from infected districts was associated with higher infection risk in slaughterhouse workers. The finding that anthropogenic rather than environmental factors are the main drivers of RVF infection in humans can be used to design better prevention and early detection in the case of RVF resurgence in the region.

Impact of In-Cloud Aqueous Processes on the Chemistry and Transport of Biogenic Volatile Organic Compounds

NASA Astrophysics Data System (ADS)

Li, Yang; Barth, Mary C.; Patton, Edward G.; Steiner, Allison L.

2017-10-01

We investigate the impacts of cloud aqueous processes on the chemistry and transport of biogenic volatile organic compounds (BVOC) using the National Center for Atmospheric Research's large-eddy simulation code with an updated chemical mechanism that includes both gas- and aqueous-phase reactions. We simulate transport and chemistry for a meteorological case with a diurnal pattern of nonprecipitating cumulus clouds from the Baltimore-Washington area DISCOVER-AQ campaign. We evaluate two scenarios with and without aqueous-phase chemical reactions. In the cloud layer (2-3 km), the addition of aqueous phase reactions decreases HCHO by 18% over the domain due to its solubility and the fast depletion from aqueous reactions, resulting in a corresponding decrease in radical oxidants (e.g., 18% decrease in OH). The decrease of OH increases the mixing ratios of isoprene and methacrolein (MACR) (100% and 15%, respectively) in the cloud layer because the reaction rate is lower. Aqueous-phase reactions can modify the segregation between OH and BVOC by changing the sign of the segregation intensity, causing up to 55% reduction in the isoprene-OH reaction rate and 40% reduction for the MACR-OH reaction when clouds are present. Analysis of the isoprene-OH covariance budget shows the chemistry term is the primary driver of the strong segregation in clouds, triggered by the decrease in OH. All organic acids except acetic acid are formed only through aqueous-phase reactions. For acids formed in the aqueous phase, turbulence mixes these compounds on short time scales, with the near-surface mixing ratios of these acids reaching 20% of the mixing ratios in the cloud layer within 1 h of cloud formation.

Cyclists and drivers in road interactions: A comparison of perceived crash risk.

PubMed

Chaurand, Nadine; Delhomme, Patricia

2013-01-01

Today's increase in the number of cyclists has triggered a change in the interactions to be handled by road users. However, few studies have investigated crash risk perceived by cyclists interacting with other users, and few have compared cyclists' and drivers' perceptions of crash risk in bike-car interactions, the most dangerous situation for cyclists. Our aims here are to study perceived crash risk (no matter the seriousness of the crash) in six common road situations during which cyclist crashes are frequent and also to study cyclists' and drivers' perceived risk in bike-car interactions, in comparison to other interaction types (cyclist vs. cyclist and driver vs. driver). We predicted that perceived risk of being involved in a crash during a particular interaction would be greater when in interaction with a car than with a bike, and that drivers would perceive more risk than cyclists would. We also predicted that perceived risk would decrease with drivers' and cyclists' experience of their transportation mode and their perceived control over the interaction situation. We ran an online survey on two samples, experienced cyclists (N=336) and non-cyclist car drivers (N=92). Participants evaluated their personal risk - as cyclists or as drivers - of being involved in a road crash if they were in an interaction with a bike or a car for each of six risky road situations. Experience was measured in terms of years of vehicle driving and driven km; perceived control was measured in terms of perceived skill and responsibility for the risky behavior. The results validated our hypotheses: perceived risk was higher for car drivers than for cyclists and for interacting with a car than with a bike. The implications of these results for interventions to improve road safety for both cyclists and car drivers are discussed. Copyright © 2012 Elsevier Ltd. All rights reserved.

Sedimentary dynamics and high-frequency sequence stratigraphy of the southwestern slope of Great Bahama Bank

NASA Astrophysics Data System (ADS)

Wunsch, Marco; Betzler, Christian; Eberli, Gregor P.; Lindhorst, Sebastian; Lüdmann, Thomas; Reijmer, John J. G.

2018-01-01

New geophysical data from the leeward slope of Great Bahama Bank show how contour currents shape the slope and induce re-sedimentation processes. Along slope segments with high current control, drift migration and current winnowing at the toe of slope form a deep moat. Here, the slope progradation is inhibited by large channel incisions and the accumulation of large mass transport complexes, triggered by current winnowing. In areas where the slope is bathed by weaker currents, the accumulation of mass transport complexes and channel incision is rather controlled by the position of the sea level. Large slope failures were triggered during the Mid-Pleistocene transition and Mid-Brunhes event, both periods characterized by changes in the cyclicity or the amplitude of sea-level fluctuations. Within the seismic stratigraphic framework of third order sequences, four sequences of higher order were identified in the succession of the upper Pleistocene. These higher order sequences also show clear differences in function of the slope exposure to contour currents. Two stochastic models emphasize the role of the contour currents and slope morphology in the facies distribution in the upper Pleistocene sequences. In areas of high current influence the interplay of erosional and depositional processes form a complex facies pattern with downslope and along strike facies alterations. In zones with lower current influence, major facies alternations occur predominately in downslope direction, and a layer-cake pattern characterizes the along strike direction. Therefore, this study highlights that contour currents are an underestimated driver for the sediment distribution and architecture of carbonate slopes.

Detection of gene communities in multi-networks reveals cancer drivers

NASA Astrophysics Data System (ADS)

Cantini, Laura; Medico, Enzo; Fortunato, Santo; Caselle, Michele

2015-12-01

We propose a new multi-network-based strategy to integrate different layers of genomic information and use them in a coordinate way to identify driving cancer genes. The multi-networks that we consider combine transcription factor co-targeting, microRNA co-targeting, protein-protein interaction and gene co-expression networks. The rationale behind this choice is that gene co-expression and protein-protein interactions require a tight coregulation of the partners and that such a fine tuned regulation can be obtained only combining both the transcriptional and post-transcriptional layers of regulation. To extract the relevant biological information from the multi-network we studied its partition into communities. To this end we applied a consensus clustering algorithm based on state of art community detection methods. Even if our procedure is valid in principle for any pathology in this work we concentrate on gastric, lung, pancreas and colorectal cancer and identified from the enrichment analysis of the multi-network communities a set of candidate driver cancer genes. Some of them were already known oncogenes while a few are new. The combination of the different layers of information allowed us to extract from the multi-network indications on the regulatory pattern and functional role of both the already known and the new candidate driver genes.

Autonomous vehicles' disengagements: Trends, triggers, and regulatory limitations.

PubMed

Favarò, Francesca; Eurich, Sky; Nader, Nazanin

2018-01-01

Autonomous Vehicle (AV) technology is quickly becoming a reality on US roads. Testing on public roads is currently undergoing, with many AV makers located and testing in Silicon Valley, California. The California Department of Motor Vehicles (CA DMV) currently mandates that any vehicle tested on California public roads be retrofitted to account for a back-up human driver, and that data related to disengagements of the AV technology be publicly available. Disengagements data is analyzed in this work, given the safety-critical role of AV disengagements, which require the control of the vehicle to be handed back to the human driver in a safe and timely manner. This study provides a comprehensive overview of the fragmented data obtained from AV manufacturers testing on California public roads from 2014 to 2017. Trends of disengagement reporting, associated frequencies, average mileage driven before failure, and an analysis of triggers and contributory factors are here presented. The analysis of the disengagements data also highlights several shortcomings of the current regulations. The results presented thus constitute an important starting point for improvements on the current drafts of the testing and deployment regulations for autonomous vehicles on public roads. Copyright © 2017 Elsevier Ltd. All rights reserved.

Electron holes appear to trigger cancer-implicated mutations

NASA Astrophysics Data System (ADS)

Miller, John; Villagran, Martha

Malignant tumors are caused by mutations, which also affect their subsequent growth and evolution. We use a novel approach, computational DNA hole spectroscopy [M.Y. Suarez-Villagran & J.H. Miller, Sci. Rep. 5, 13571 (2015)], to compute spectra of enhanced hole probability based on actual sequence data. A hole is a mobile site of positive charge created when an electron is removed, for example by radiation or contact with a mutagenic agent. Peaks in the hole spectrum depict sites where holes tend to localize and potentially trigger a base pair mismatch during replication. Our studies of reveal a correlation between hole spectrum peaks and spikes in human mutation frequencies. Importantly, we also find that hole peak positions that do not coincide with large variant frequencies often coincide with cancer-implicated mutations and/or (for coding DNA) encoded conserved amino acids. This enables combining hole spectra with variant data to identify critical base pairs and potential cancer `driver' mutations. Such integration of DNA hole and variance spectra could also prove invaluable for pinpointing critical regions, and sites of driver mutations, in the vast non-protein-coding genome. Supported by the State of Texas through the Texas Ctr. for Superconductivity.

Multifunctional pulse generator for high-intensity focused ultrasound system

NASA Astrophysics Data System (ADS)

Tamano, Satoshi; Yoshizawa, Shin; Umemura, Shin-Ichiro

2017-07-01

High-intensity focused ultrasound (HIFU) can achieve high spatial resolution for the treatment of diseases. A major technical challenge in implementing a HIFU therapeutic system is to generate high-voltage high-current signals for effectively exciting a multichannel HIFU transducer at high efficiencies. In this paper, we present the development of a multifunctional multichannel generator/driver. The generator can produce a long burst as well as an extremely high-voltage short pulse of pseudosinusoidal waves (trigger HIFU) and second-harmonic superimposed waves for HIFU transmission. The transmission timing, waveform, and frequency can be controlled using a field-programmable gate array (FPGA) via a universal serial bus (USB) microcontroller. The hardware is implemented in a compact printed circuit board. The test results of trigger HIFU reveal that the power consumption and the temperature rise of metal-oxide semiconductor field-effect transistors were reduced by 19.9% and 38.2 °C, respectively, from the previous design. The highly flexible performance of the novel generator/driver is demonstrated in the generation of second-harmonic superimposed waves, which is useful for cavitation-enhanced HIFU treatment, although the previous design exhibited difficulty in generating it.

Oxygen, ecology, and the Cambrian radiation of animals

NASA Astrophysics Data System (ADS)

Sperling, Erik A.; Frieder, Christina A.; Raman, Akkur V.; Girguis, Peter R.; Levin, Lisa A.; Knoll, Andrew H.

2013-08-01

The Proterozoic-Cambrian transition records the appearance of essentially all animal body plans (phyla), yet to date no single hypothesis adequately explains both the timing of the event and the evident increase in diversity and disparity. Ecological triggers focused on escalatory predator-prey "arms races" can explain the evolutionary pattern but not its timing, whereas environmental triggers, particularly ocean/atmosphere oxygenation, do the reverse. Using modern oxygen minimum zones as an analog for Proterozoic oceans, we explore the effect of low oxygen levels on the feeding ecology of polychaetes, the dominant macrofaunal animals in deep-sea sediments. Here we show that low oxygen is clearly linked to low proportions of carnivores in a community and low diversity of carnivorous taxa, whereas higher oxygen levels support more complex food webs. The recognition of a physiological control on carnivory therefore links environmental triggers and ecological drivers, providing an integrated explanation for both the pattern and timing of Cambrian animal radiation.

Thin-Layer Composite Unimorph Ferroelectric Driver Sensor Properties

NASA Technical Reports Server (NTRS)

Mossi, Karla M.; Selby, Gregory V.; Bryant, Robert G.

1998-01-01

Tests were conducted on 13 different configurations of a new class of piezoelectric devices called THUNDER (thin layer composite unimorph ferroelectric driver and sensor). These configurations consisted of a combination of 1, 3, 5, 7, and 9 layers of 25.4 micron thick aluminium as a backing material, with and without a top layer of 25.4 micrometer aluminum. All of these configurations used the same piezoelectric ceramic wafer (PZT-5A) with dimensions of 5.08 x 3.81 x 0.018 cm. The above configurations were tested at two stages of the manufacturing process: before and after repoling. The parameters measured included frequency, driving voltage. displacement, capacitance, and radius of curvature. An optic sensor recorded the displacement at a fixed voltage(100 - 400 V peak to peak) over a predetermined frequency range (1 - 1000 Hz). These displacement measurements were performed using a computer that controlled the process of activating and measuring the displacement of the device. A parameter alpha was defined which can be used to predict the which configuration will produce the most displacement for a free standing device.

Biocatalysis: Unmasked by stretching

NASA Astrophysics Data System (ADS)

Kharlampieva, Eugenia; Tsukruk, Vladimir V.

2009-09-01

The biocatalytic activity of enzyme-loaded responsive layer-by-layer films can be switched on and off by simple mechanical stretching. Soft materials could thus be used to trigger biochemical reactions under mechanical action, with potential therapeutic applications.

Muon Trigger for Mobile Phones

NASA Astrophysics Data System (ADS)

Borisyak, M.; Usvyatsov, M.; Mulhearn, M.; Shimmin, C.; Ustyuzhanin, A.

2017-10-01

The CRAYFIS experiment proposes to use privately owned mobile phones as a ground detector array for Ultra High Energy Cosmic Rays. Upon interacting with Earth’s atmosphere, these events produce extensive particle showers which can be detected by cameras on mobile phones. A typical shower contains minimally-ionizing particles such as muons. As these particles interact with CMOS image sensors, they may leave tracks of faintly-activated pixels that are sometimes hard to distinguish from random detector noise. Triggers that rely on the presence of very bright pixels within an image frame are not efficient in this case. We present a trigger algorithm based on Convolutional Neural Networks which selects images containing such tracks and are evaluated in a lazy manner: the response of each successive layer is computed only if activation of the current layer satisfies a continuation criterion. Usage of neural networks increases the sensitivity considerably comparable with image thresholding, while the lazy evaluation allows for execution of the trigger under the limited computational power of mobile phones.

Influences of meteorological parameters on indoor radon concentrations (222Rn) excluding the effects of forced ventilation and radon exhalation from soil and building materials.

PubMed

Schubert, Michael; Musolff, Andreas; Weiss, Holger

2018-06-13

Elevated indoor radon concentrations ( 222 Rn) in dwellings pose generally a potential health risk to the inhabitants. During the last decades a considerable number of studies discussed both the different sources of indoor radon and the drivers for diurnal and multi day variations of its concentration. While the potential sources are undisputed, controversial opinions exist regarding their individual relevance and regarding the driving influences that control varying radon indoor concentrations. These drivers include (i) cyclic forced ventilation of dwellings, (ii) the temporal variance of the radon exhalation from soil and building materials due to e.g. a varying moisture content and (iii) diurnal and multi day temperature and pressure patterns. The presented study discusses the influences of last-mentioned temporal meteorological parameters by effectively excluding the influences of forced ventilation and undefined radon exhalation. The results reveal the continuous variation of the indoor/outdoor pressure gradient as key driver for a constant "breathing" of any interior space, which affects the indoor radon concentration with both diurnal and multi day patterns. The diurnally recurring variation of the pressure gradient is predominantly triggered by the day/night cycle of the indoor temperature that is associated with an expansion/contraction of the indoor air volume. Multi day patterns, on the other hand, are mainly due to periods of negative air pressure indoors that is triggered by periods of elevated wind speeds as a result of Bernoulli's principle. Copyright © 2018 Elsevier Ltd. All rights reserved.

Assessing driving forces of land use and land cover change by a mixed-method approach in north-eastern Ghana, West Africa.

PubMed

Kleemann, Janina; Baysal, Gülendam; Bulley, Henry N N; Fürst, Christine

2017-07-01

Land use and land cover change (LULCC) is the result of complex human-environmental interactions. The high interdependencies in social-ecological systems make it difficult to identify the main drivers. However, knowledge of key drivers of LULCC, including indirect (underlying) drivers which cannot be easily determined by spatial or economic analyses, is essential for land use planning and especially important in developing countries. We used a mixed-method approach in order to detect drivers of LULCC in the Upper East Region of northern Ghana by different qualitative and quantitative methods which were compared in a confidence level analysis. Viewpoints from experts help to answer why the land use is changing, since many triggering effects, especially non-spatial and indirect drivers of LULCC, are not measurable by other methodological approaches. Geo-statistical or economic analyses add to validate the relevance of the expert-based results. First, we conducted in-depth interviews and developed a list of 34 direct and indirect drivers of LULCC. Subsequently, a group of experts was asked in a questionnaire to select the most important drivers by using a Likert scale. This information was complemented by remote sensing analysis. Finally, the driver analysis was compared to information from literature. Based on these analyses there is a very high confidence that population growth, especially in rural areas, is a major driver of LULCC. Further, current farming practice, bush fires, livestock, the road network and climate variability were the main direct drivers while the financial capital of farmers and customary norms regarding land tenure were listed as important indirect drivers with high confidence. Many of these driving forces, such as labour shortage and migration, are furthermore interdependent. Governmental laws, credits, the service by extension officers, conservational agriculture and foreign agricultural medium-scale investments are currently not driving land use changes. We conclude that the mixed-method approach improves the confidence of findings and the selection of most important drivers for modelling LULCC, especially in developing countries. Copyright © 2017 Elsevier Ltd. All rights reserved.

Phosphorus in agricultural soils: drivers of its distribution at the global scale

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ringeval, Bruno; Augusto, Laurent; Monod, Herve

Phosphorus (P) availability in soils limits crop yields in many regions of the world, while excess of soil P triggers aquatic eutrophication in other regions. Numerous processes drive the global spatial distribution of P in agricultural soils, but their relative roles remain unclear. Here, we combined several global datasets describing these drivers with a soil P dynamics model to simulate the distribution of P in agricultural soils and to assess the contributions of the different drivers at the global scale. We analyzed both the labile inorganic P (P ILAB), a proxy of the pool involved in plant nutrition and themore » total soil P (P TOT). We found that the soil biogeochemical background (BIOG) and farming practices (FARM) were the main drivers of the spatial variability in cropland soil P content but that their contribution varied between P TOT vs P ILAB. Indeed, 97% of the P TOT spatial variability could be explained by BIOG, while BIOG and FARM explained 41% and 58% of P ILAB spatial variability, respectively. Other drivers such as climate, soil erosion, atmospheric P deposition and soil buffering capacity made only very small contribution. Lastly, our study is a promising approach to investigate the potential effect of P as a limiting factor for agricultural ecosystems and for global food production. Additionally, we quantified the anthropogenic perturbation of P cycle and demonstrated how the different drivers are combined to explain the global distribution of agricultural soil P.« less

Impaired driving from medical conditions: A 70-year-old man trying to decide if he should continue driving

PubMed Central

Rizzo, Matthew

2012-01-01

Some medical disorders can impair performance, increasing the risk of driving safety errors that can lead to vehicle crashes. The causal pathway often involves a concatenation of factors or events, some of which can be prevented or controlled. Effective interventions can operate before, during, or after a crash occurs at the levels of driver capacity, vehicle and road design, and public policy. A variety of systemic, neurological, psychiatric, and developmental disorders put drivers at potential increased risk of a car crash in the short or long term. Medical diagnosis and age alone are usually insufficient criteria for determining fitness to drive. Strategies are needed for determining what types and levels of reduced function provide a threshold for disqualification in drivers with medical disorders. Evidence of decreased mileage, self-restriction to driving in certain situations, collisions, moving violations, aggressive driving, sleepiness, alcohol abuse, metabolic disorders, and multiple medications may trigger considerations of driver safety. A general framework for evaluating driver fitness relies on a functional evaluation of multiple domains (cognitive, motor, perceptual, and psychiatric) that are important for safe driving and can be applied across many disorders, including conditions that have rarely been studied with respect to driving, and in patients with multiple conditions and medications. Neurocognitive tests, driving simulation, and road tests provide complementary sources of evidence to evaluate driver safety. No single test is sufficient to determine who should drive and who should not. PMID:21364126

Impaired driving from medical conditions: a 70-year-old man trying to decide if he should continue driving.

PubMed

Rizzo, Matthew

2011-03-09

Some medical disorders can impair performance, increasing the risk of driving safety errors that can lead to vehicle crashes. The causal pathway often involves a concatenation of factors or events, some of which can be prevented or controlled. Effective interventions can operate before, during, or after a crash occurs at the levels of driver capacity, vehicle and road design, and public policy. A variety of systemic, neurological, psychiatric, and developmental disorders put drivers at potential increased risk of a car crash in the short or long term. Medical diagnosis and age alone are usually insufficient criteria for determining fitness to drive. Strategies are needed for determining what types and levels of reduced function provide a threshold for disqualification in drivers with medical disorders. Evidence of decreased mileage, self-restriction to driving in certain situations, collisions, moving violations, aggressive driving, sleepiness, alcohol abuse, metabolic disorders, and multiple medications may trigger considerations of driver safety. A general framework for evaluating driver fitness relies on a functional evaluation of multiple domains (cognitive, motor, perceptual, and psychiatric) that are important for safe driving and can be applied across many disorders, including conditions that have rarely been studied with respect to driving, and in patients with multiple conditions and medications. Neurocognitive tests, driving simulation, and road tests provide complementary sources of evidence to evaluate driver safety. No single test is sufficient to determine who should drive and who should not.

Near-infrared spectroscopy assessment of divided visual attention task-invoked cerebral hemodynamics during prolonged true driving

NASA Astrophysics Data System (ADS)

Li, Ting; Zhao, Yue; Sun, Yunlong; Gao, Yuan; Su, Yu; Hetian, Yiyi; Chen, Min

2015-03-01

Driver fatigue is one of the leading causes of traffic accidents. It is imperative to develop a technique to monitor fatigue of drivers in real situation. Near-infrared spectroscopy (fNIRS) is now capable of measuring brain functional activity noninvasively in terms of hemodynamic responses sensitively, which shed a light to us that it may be possible to detect fatigue-specified brain functional activity signal. We developed a sensitive, portable and absolute-measure fNIRS, and utilized it to monitor cerebral hemodynamics on car drivers during prolonged true driving. An odd-ball protocol was employed to trigger the drivers' visual divided attention, which is a critical function in safe driving. We found that oxyhemoglobin concentration and blood volume in prefrontal lobe dramatically increased with driving duration (stand for fatigue degree; 2-10 hours), while deoxyhemoglobin concentration increased to the top at 4 hours then decreased slowly. The behavior performance showed clear decrement only after 6 hours. Our study showed the strong potential of fNIRS combined with divided visual attention protocol in driving fatigue degree monitoring. Our findings indicated the fNIRS-measured hemodynamic parameters were more sensitive than behavior performance evaluation.

River logjams cause frequent large-scale forest die-off events in southwestern Amazonia

NASA Astrophysics Data System (ADS)

Lombardo, Umberto

2017-07-01

This paper investigates the dynamics of logjam-induced floods and alluvial deposition in the Bolivian Amazon and the effects these have on forest disturbance and recovery cycles. It expands on previous work by Gullison et al. (1996) who reported a case of catastrophic floods triggered by logjams in the Chimane Forest in the Bolivian Amazon. No further studies have followed up on this observation and no research has been published on the effects of large wood in tropical lowland rivers. The study is based on the analysis of a time series of Landsat imagery (1984-2016) and field evidence. Results show that logjam-induced floods are a major driver of forest disturbance along the Andean piedmont in the Bolivian Amazon. New logjams form on an almost yearly basis, always further upriver, until an avulsion takes place. Logjam-induced floods are characterized here by the sudden deposition of a thick sand layer and the death of forest in a V-shaped area. The Bolivian Amazon offers a unique opportunity for further research on how large wood affects river behavior in lowland tropical settings and how large and frequent forest disturbance events resulting from river logjams affect forest biodiversity and community successions.

Taped Random Spectra for Reliability Demonstration Testing

DTIC Science & Technology

1981-04-01

circuit , barrier strip terminals 9A and 9B. Closure of the normally-open contacts provides the gate current necessary to trigger the control TRIAC ... Circuit contains a TRIAC , DIAC, Reed Relay (R3) and the Tape Running Relay Driver. The Cam on/off switching is accomplished through the barrier strip...2-25 2I; Input Power Circuit .. .. .... ...... ...... ...... ........... 2-26 2-13 Typical Control Circuit

The role of Energy Deposition in the Epitaxial Layer in Triggering SEGR in Power MOSFETs

NASA Technical Reports Server (NTRS)

Selva, L.; Swift, G.; Taylor, W.; Edmonds, L.

1999-01-01

In these SEGR experiments, three identical-oxide MOSFET types were irradiated with six ions of significantly different ranges. Results show the prime importance of the total energy deposited in the epitaxial layer.

Plant immunity triggered by microbial molecular signatures.

PubMed

Zhang, Jie; Zhou, Jian-Min

2010-09-01

Pathogen/microbe-associated molecular patterns (PAMPs/MAMPs) are recognized by host cell surface-localized pattern-recognition receptors (PRRs) to activate plant immunity. PAMP-triggered immunity (PTI) constitutes the first layer of plant immunity that restricts pathogen proliferation. PTI signaling components often are targeted by various Pseudomonas syringae virulence effector proteins, resulting in diminished plant defenses and increased bacterial virulence. Some of the proteins targeted by pathogen effectors have evolved to sense the effector activity by associating with cytoplasmic immune receptors classically known as resistance proteins. This allows plants to activate a second layer of immunity termed effector-triggered immunity (ETI). Recent studies on PTI regulation and P. syringae effector targets have uncovered new components in PTI signaling. Although MAP kinase (MAPK) cascades have been considered crucial for PTI, emerging evidence indicates that a MAPK-independent pathway also plays an important role in PTI signaling.

Forward Collision Warning: Clues to Optimal Timing of Advisory Warnings

PubMed Central

Aksan, Nazan; Sager, Lauren; Hacker, Sarah; Marini, Robert; Dawson, Jeffrey; Anderson, Steven; Rizzo, Matthew

2016-01-01

We examined the effectiveness of a heads-up Forward Collision Warning (FCW) system in 39 younger to middle aged drivers (25-50, mean = 35 years) and 37 older drivers (66-87, mean = 77 years). The warnings were implemented in a fixed based, immersive, 180 degree forward field of view simulator. The FCW included a visual advisory component consisting of a red horizontal bar which flashed in the center screen of the simulator that was triggered at time-to-collision (TTC) 4 seconds. The bar roughly overlapped the rear bumper of the lead vehicle, just below the driver's line-of-sight. A sustained auditory tone (~80 dB) was activated at TTC=2 to alert the driver to an imminent collision. Hence, the warning system differed from the industry standard in significant ways. 95% Confidence intervals for the safety gains ranged from −.03 to .19 seconds in terms of average correction time across several activations. Older and younger adults did not differ in terms of safety gains. Closer inspection of data revealed that younger to middle aged drivers were already braking (42%) on a larger proportion of FCW activations than older drivers (26%), p < .001. Conversely, older drivers were still accelerating (38%) on a larger proportion of FCW activations than younger to middle aged drivers (23%) at the time FCW was activated, p < .009. There were no differences in the proportion of activations when drivers were coasting at the time FCW was activated, p = .240. Furthermore, large individual differences in basic visual, motor, and cognitive function predicted the tendency to brake prior to FCW activation. Those who tended to be better functioning in each of these domains were more likely to be already braking prior to FCW activation at the fixed threshold of TTC=4. These findings suggest optimal timing for advisory alerts for forward events may need to be larger than TTC=4. PMID:27648455

An eddy-viscosity treatment of the unsteady turbulent boundary layer on a flat plate in an expansion tube

NASA Technical Reports Server (NTRS)

Gupta, R. N.; Trimpi, R. L.

1974-01-01

An analysis is presented for the relaxation of a turbulent boundary layer on a semiinfinite flat plate after passage of a shock wave and a trailing driver gas-driven gas interface. The problem has special application to expansion tube flows. The flow-governing equations have been transformed into the Lamcrocco variables. The numerical results indicate that a fully turbulent boundary layer relaxes faster to the final steady-state values of heat transfer and skin-friction than a fully laminar boundary layer.

Synthesis of CO2/N2-triggered reversible stability-controllable poly(2-(diethylamino)ethyl methacrylate)-grafted-AuNPs by surface-initiated atom transfer radical polymerization.

PubMed

Kitayama, Yukiya; Takeuchi, Toshifumi

2014-10-28

CO2/N2-triggered stability-controllable gold nanoparticles (AuNPs) grafted with poly(2-(diethylamino)ethyl methacrylate) (PDEAEMA) layers (PDEAEMA-g-AuNPs) were synthesized by the surface-initiated atom transfer radical polymerization of DEAEMA with AuNPs bearing the bis[2-(2-bromoisobutyryloxy)undecyl] layer (grafting from method). Extension of the PDEAEMA chain length increased the stability of the PDEAEMA-g-AuNPs in CO2-bubbled water because of the electrosteric repulsion of the protonated PDEAEMA layer. The chain-length-dependent stability of PDEAEMA-g-AuNPs was confirmed by DLS and UV-vis spectra by using the localized surface plasmon resonance property of the AuNPs, where the extinction wavelength was shifted toward shorter wavelength with increasing PDEAEMA chain length. The reversible stability change with the gas stimuli of CO2/N2 was also successfully demonstrated. Finally, the transfer across the immiscible interface between water and organic solvent was successfully demonstrated by N2-triggered insolubilization of PDEAEMA layer on AuNPs in the aqueous phase, leading to the successful collection of AuNPs using organic solvent from the aqueous phase. Our "grafting from" method of reversible stability-controllable AuNPs can be applied to develop advanced materials such as reusable optical AuNP-based nanosensors because the molecular recognition layer can be constructed by two-step polymerization.

Drivers' communicative interactions: on-road observations and modelling for integration in future automation systems.

PubMed

Portouli, Evangelia; Nathanael, Dimitris; Marmaras, Nicolas

2014-01-01

Social interactions with other road users are an essential component of the driving activity and may prove critical in view of future automation systems; still up to now they have received only limited attention in the scientific literature. In this paper, it is argued that drivers base their anticipations about the traffic scene to a large extent on observations of social behaviour of other 'animate human-vehicles'. It is further argued that in cases of uncertainty, drivers seek to establish a mutual situational awareness through deliberate communicative interactions. A linguistic model is proposed for modelling these communicative interactions. Empirical evidence from on-road observations and analysis of concurrent running commentary by 25 experienced drivers support the proposed model. It is suggested that the integration of a social interactions layer based on illocutionary acts in future driving support and automation systems will improve their performance towards matching human driver's expectations. Practitioner Summary: Interactions between drivers on the road may play a significant role in traffic coordination. On-road observations and running commentaries are presented as empirical evidence to support a model of such interactions; incorporation of drivers' interactions in future driving support and automation systems may improve their performance towards matching driver's expectations.

LSTM, GRU, Highway and a Bit of Attention: An Empirical Overview for Language Modeling in Speech Recognition

DTIC Science & Technology

2016-09-12

on learning word triggers with an attention mechanism. 5.1. Model descriptions 5.1.1. Attention layer A minimalistic attention mechanism can be...word trigger model based on a minimalistic attention mechanism: it already showed some interesting qualitative re- sults, while the performance was not

Knowledge-Driven Creative Destruction, or Leveraging Knowledge for Competitive Advantage: Strategic Knowledge Arbitrage and Serendipity as Real Options Drivers Triggered by Co-Opetition, Co-Evolution and Co-Specialization

ERIC Educational Resources Information Center

Carayannis, Elias G.

2008-01-01

In today's globalizing and hypercompetitive marketplace, knowledge and learning are the only capabilities that can provide sustained competitive advantage. "Knowledge" is the content of learning, and a firm gains competitive superiority either by knowing something that its competitors do not know or by having a certain type of knowledge that…

Discrete element simulation of the Jiufengershan rock-and-soil avalanche triggered by the 1999 Chi-Chi earthquake, Taiwan

NASA Astrophysics Data System (ADS)

Chang, Kuo-Jen; Taboada, Alfredo

2009-09-01

We present Contact Dynamics discrete element simulations of the earthquake-triggered Jiufengershan avalanche, which mobilized a 60 m thick, 1.5 km long sedimentary layer, dipping ˜22°SE toward a valley. The dynamic behavior of the avalanche is simulated under different assumptions about rock behavior, water table height, and boundary shear strength. Additionally, seismic shaking is introduced using strong motion records from nearby stations. We assume that seismic shaking generates shearing and frictional heating along the surface of rupture, which, in turn, may induce dynamic weakening and avalanche triggering; a simple "slip-weakening" criterion was adopted to simulate shear strength drop along the rupture surface. We investigate the mechanical processes occurring during triggering and propagation of an avalanche mobilizing shallowly dipping layers. Incipient deformation forms a pop-up structure at the toe of the dip slope. As the avalanche propagates, the pop-up deforms into an overturned fold, which overrides the surface of separation along a décollement. Simultaneously, uphill layers slide at high velocity (125 km/h) and are folded and disrupted as they reach the toe of the dip slope. The avalanche foot forms a wedge that is pushed forward as deformed rocks accrete at its rear. We simulated five cross sections across the Jiufengershan avalanche, which differ in the geometry of the surface of separation. Topographic and simulated surface profiles are similar. The friction coefficient at the surface of separation determined from back analysis is abnormally low (μSS = 0.2), possibly due to lubrication by liquefied soils. The granular deposits of simulated earthquake- and rain-triggered avalanches are similar.

The distraction effects of phone use during a crucial driving maneuver.

PubMed

Hancock, P A; Lesch, M; Simmons, L

2003-07-01

Forty-two licensed drivers were tested in an experiment that required them to respond to an in-vehicle phone at the same time that they were faced with making a crucial stopping decision. Using test track facilities, we also examined the influence of driver gender and driver age on these dual-task response capacities. Each driver was given task practice and then performed a first block of 24 trials, where one trial represented one circuit of the test track. Half of the trials were control conditions in which neither the stop-light was activated nor was the in-vehicle phone triggered. Four trials required only stop-light response and a further four, phone response only. The remaining four trials required the driver to complete each task simultaneously. The order of presentation of specific trials was randomized and the whole sequence was repeated in a second block giving 48 trials per driver. In-vehicle phone response also contained an embedded memory task that was evaluated at the end of each trial circuit. Results confirmed our previous observation that in the dual-task condition there was a slower response to the light change. To compensate for this slowed response, drivers subsequently brake more intensely. Most importantly, we recorded a critical 15% increase in non-response to the stop-light in the presence of the phone distraction task which equates with increased stop-light violations on the open road. These response patterns varied by driver age and driver gender. In particular, age had a large effect on task components that required speed of response to multiple, simultaneous demands. Since driving represents a highly complex and interactive environment, it is not possible to specify a simplistic relationship between these distraction effects and outcome crash patterns. However, we can conclude that such in-vehicle technologies erode performance safety margin and distract drivers from their critical primary task of vehicle control. As such it can be anticipated that a causal relation exists to collision events. This is a crucial concern for all in-vehicle device designers and for the many safety researchers and professionals seeking to reduce the adverse impacts of vehicle collisions.

Electric field-triggered metal-insulator transition resistive switching of bilayered multiphasic VOx

NASA Astrophysics Data System (ADS)

Won, Seokjae; Lee, Sang Yeon; Hwang, Jungyeon; Park, Jucheol; Seo, Hyungtak

2018-01-01

Electric field-triggered Mott transition of VO2 for next-generation memory devices with sharp and fast resistance-switching response is considered to be ideal but the formation of single-phase VO2 by common deposition techniques is very challenging. Here, VOx films with a VO2-dominant phase for a Mott transition-based metal-insulator transition (MIT) switching device were successfully fabricated by the combined process of RF magnetron sputtering of V metal and subsequent O2 annealing to form. By performing various material characterizations, including scanning transmission electron microscopy-electron energy loss spectroscopy, the film is determined to have a bilayer structure consisting of a VO2-rich bottom layer acting as the Mott transition switching layer and a V2O5/V2O3 mixed top layer acting as a control layer that suppresses any stray leakage current and improves cyclic performance. This bilayer structure enables excellent electric field-triggered Mott transition-based resistive switching of Pt-VOx-Pt metal-insulator-metal devices with a set/reset current ratio reaching 200, set/reset voltage of less than 2.5 V, and very stable DC cyclic switching upto 120 cycles with a great set/reset current and voltage distribution less than 5% of standard deviation at room temperature, which are specifications applicable for neuromorphic or memory device applications. [Figure not available: see fulltext.

Oxygen, ecology, and the Cambrian radiation of animals

PubMed Central

Sperling, Erik A.; Frieder, Christina A.; Raman, Akkur V.; Girguis, Peter R.; Levin, Lisa A.; Knoll, Andrew H.

2013-01-01

The Proterozoic-Cambrian transition records the appearance of essentially all animal body plans (phyla), yet to date no single hypothesis adequately explains both the timing of the event and the evident increase in diversity and disparity. Ecological triggers focused on escalatory predator–prey “arms races” can explain the evolutionary pattern but not its timing, whereas environmental triggers, particularly ocean/atmosphere oxygenation, do the reverse. Using modern oxygen minimum zones as an analog for Proterozoic oceans, we explore the effect of low oxygen levels on the feeding ecology of polychaetes, the dominant macrofaunal animals in deep-sea sediments. Here we show that low oxygen is clearly linked to low proportions of carnivores in a community and low diversity of carnivorous taxa, whereas higher oxygen levels support more complex food webs. The recognition of a physiological control on carnivory therefore links environmental triggers and ecological drivers, providing an integrated explanation for both the pattern and timing of Cambrian animal radiation. PMID:23898193

A novel microsphere with a three-layer structure for duodenum-specific drug delivery.

PubMed

Zhu, Xi; Zhou, Dan; Jin, Yun; Song, Yu-pin; Zhang, Zhi-rong; Huang, Yuan

2011-07-15

Owing to the quick elimination of drug from duodenum and the depth of Helicobacter pylori (H. pylori) colonized in mucus, antibiotic therapy often fails in the eradication of H. pylori infection for duodenal ulcer. A novel duodenum-specific microsphere (DSM) consisting of three-layer structure was developed to enhance the drug concentration and retention time in duodenal mucus layer. Firstly a core-shell mucoadhesive microsphere was prepared with a novel emulsification/coagulation coating method by introducing drug loaded Eudragit cores into a thiolated chitosan mucoadhesive layer. Then the obtained core-shell mucoadhesive microspheres were further coated with hydroxypropyl methylcellulose acetate maleate as the pH-sensitive layer for the trigger of mucoadhesion and drug release in duodenum. From the fluorescence microscopic and scanning electron microscopic images, the three-layer structure was successfully established. The microspheres exhibited a duodenum-specific trigger performance, good mucoadhesive property and pH-dependent drug release. In vivo study performed in rats demonstrated that DSM exhibited about 3-fold augmentation of AUC and about 5-fold augmentation of C(max) for duodenal mucus drug concentration compared with free drug suspension. These results suggest that the three-layer structure microspheres may provide a promising approach for duodenum-targeting drug delivery system. Copyright © 2011 Elsevier B.V. All rights reserved.

Molecular and Dusty Layers of Asymptotic Giant Branch Stars Studied with the VLT Interferometer

DTIC Science & Technology

2011-09-01

the evolution of low to intermediate mass stars towards planetary nebulae . It is also one of the most important sources of chemical enrichment of...planetary nebula (PN) phases, and is thus the most important driver for the further stellar evolution (e.g., Habing & Olofsson, 2003). Mass loss from AGB...branch (AGB) stars is the most important driver for the evolution of low to intermediate mass stars towards planetary nebulae . It is also one of the

A fuzzy gear shifting strategy for manual transmissions

NASA Astrophysics Data System (ADS)

Mashadi, B.; Kazemkhani, A.

2005-12-01

Governing parameters in decision making for gear changing of an automated manual transmission are discussed based on two different criteria, namely engine working conditions and driver's intention. By taking into consideration the effects of these parameters, gear shifting strategy is designed with the application of Fuzzy control method. The controller structure is formed in two layers. In the first layer two fuzzy inference modules are used to determine necessary outputs. In second layer a fuzzy inference module makes the decision of shifting by up-shift, downshift or maintain commands. The quality of Fuzzy controller behavior is examined by making use of ADVISOR software. It is shown that at different driving conditions the controller makes correct decisions for gear shifting accounting for dynamical requirements of vehicle. It is also shown that the controller based on both engine state and driver's intention eliminates unnecessary shiftings that are present when the intention is ignored. A micro-trip is designed in which a required speed in the form of a step function is demanded for the vehicle. Starting from rest both strategies change the gear to reach maximum speed more or less in a similar fashion. In deceleration phase, however, large differences are observed between the two strategies. The engine-state strategy is less sensitive to downshift, taking even unnecessary up shift decisions. The state-intention strategy, however, correctly interprets the driver's intention for decreasing speed and utilizes engine brake torque to reduce vehicle speed in a shorter time.

Convergence of Cortical and Sensory Driver Inputs on Single Thalamocortical Cells

PubMed Central

Groh, Alexander; Bokor, Hajnalka; Mease, Rebecca A.; Plattner, Viktor M.; Hangya, Balázs; Stroh, Albrecht; Deschenes, Martin; Acsády, László

2014-01-01

Ascending and descending information is relayed through the thalamus via strong, “driver” pathways. According to our current knowledge, different driver pathways are organized in parallel streams and do not interact at the thalamic level. Using an electron microscopic approach combined with optogenetics and in vivo physiology, we examined whether driver inputs arising from different sources can interact at single thalamocortical cells in the rodent somatosensory thalamus (nucleus posterior, POm). Both the anatomical and the physiological data demonstrated that ascending driver inputs from the brainstem and descending driver inputs from cortical layer 5 pyramidal neurons converge and interact on single thalamocortical neurons in POm. Both individual pathways displayed driver properties, but they interacted synergistically in a time-dependent manner and when co-activated, supralinearly increased the output of thalamus. As a consequence, thalamocortical neurons reported the relative timing between sensory events and ongoing cortical activity. We conclude that thalamocortical neurons can receive 2 powerful inputs of different origin, rather than only a single one as previously suggested. This allows thalamocortical neurons to integrate raw sensory information with powerful cortical signals and transfer the integrated activity back to cortical networks. PMID:23825316

Linear and nonlinear effects of temperature and precipitation on ecosystem properties in tidal saline wetlands

USGS Publications Warehouse

Feher, Laura C.; Osland, Michael J.; Griffith, Kereen T.; Grace, James B.; Howard, Rebecca J.; Stagg, Camille L.; Enwright, Nicholas M.; Krauss, Ken W.; Gabler, Christopher A.; Day, Richard H.; Rogers, Kerrylee

2017-01-01

Climate greatly influences the structure and functioning of tidal saline wetland ecosystems. However, there is a need to better quantify the effects of climatic drivers on ecosystem properties, particularly near climate-sensitive ecological transition zones. Here, we used climate- and literature-derived ecological data from tidal saline wetlands to test hypotheses regarding the influence of climatic drivers (i.e., temperature and precipitation regimes) on the following six ecosystem properties: canopy height, biomass, productivity, decomposition, soil carbon density, and soil carbon accumulation. Our analyses quantify and elucidate linear and nonlinear effects of climatic drivers. We quantified positive linear relationships between temperature and above-ground productivity and strong positive nonlinear (sigmoidal) relationships between (1) temperature and above-ground biomass and canopy height and (2) precipitation and canopy height. Near temperature-controlled mangrove range limits, small changes in temperature are expected to trigger comparatively large changes in biomass and canopy height, as mangrove forests grow, expand, and, in some cases, replace salt marshes. However, within these same transition zones, temperature-induced changes in productivity are expected to be comparatively small. Interestingly, despite the significant above-ground height, biomass, and productivity relationships across the tropical–temperate mangrove–marsh transition zone, the relationships between temperature and soil carbon density or soil carbon accumulation were not significant. Our literature review identifies several ecosystem properties and many regions of the world for which there are insufficient data to fully evaluate the influence of climatic drivers, and the identified data gaps can be used by scientists to guide future research. Our analyses indicate that near precipitation-controlled transition zones, small changes in precipitation are expected to trigger comparatively large changes in canopy height. However, there are scant data to evaluate the influence of precipitation on other ecosystem properties. There is a need for more decomposition data across climatic gradients, and to advance understanding of the influence of changes in precipitation and freshwater availability, additional ecological data are needed from tidal saline wetlands in arid climates. Collectively, our results can help scientists and managers better anticipate the linear and nonlinear ecological consequences of climate change for coastal wetlands.

Patterns and Drivers of Vertical Distribution of the Ciliate Community from the Surface to the Abyssopelagic Zone in the Western Pacific Ocean.

PubMed

Zhao, Feng; Filker, Sabine; Xu, Kuidong; Huang, Pingping; Zheng, Shan

2017-01-01

The deep sea is one of the largest but least understood ecosystems on earth. Knowledge about the diversity and distribution patterns as well as drivers of microbial eukaryote (including ciliates) along the water column, particularly below the photic zone, is scarce. In this study, we investigated the diversity of pelagic ciliates, the main group of marine microeukaryotes, their vertical distribution from the surface to the abyssopelagic zone, as well as their horizontal distribution over a distance of 1,300 km in the Western Pacific Ocean, using high-throughput DNA and cDNA (complementary DNA) sequencing. No distance-decay relationship could be detected along the horizontal scale; instead, a distinct vertical distribution within the ciliate communities was revealed. The alpha diversity of the ciliate communities in the deep chlorophyll maximum (DCM) and the 200 m layer turned out to be significantly higher compared with the other water layers. The ciliate communities in the 200 m water layer appeared to be more similar to those in deeper layers from 1,000 m to about 5,000 m than to the surface and DCM ciliate communities. Dominant species in the bathypelagic and abyssopelagic zone, particularly some parasites, were also detected in the 200 m layer, but were almost absent in the surface layer. The 200 m layer, therefore, seems to be an important "species bank" for deep ocean layers. Statistical analyses further revealed significant effects of temperature and chlorophyll a on the partitioning of ciliate diversity, indicating that environmental factors are a stronger force in shaping marine pelagic ciliate communities than the geographic distance.

Laser pumping of thyristors for fast high current rise-times

DOEpatents

Glidden, Steven C.; Sanders, Howard D.

2013-06-11

An optically triggered semiconductor switch includes an anode metallization layer; a cathode metallization layer; a semiconductor between the anode metallization layer and the cathode metallization layer and a photon source. The semiconductor includes at least four layers of alternating doping in the form P-N-P-N, in which an outer layer adjacent to the anode metallization layer forms an anode and an outer layer adjacent the cathode metallization layer forms a cathode and in which the anode metallization layer has a window pattern of optically transparent material exposing the anode layer to light. The photon source emits light having a wavelength, with the light from the photon source being configured to match the window pattern of the anode metallization layer.

Mitochondrial dysfunction as a trigger of innate immune responses and inflammation.

PubMed

West, A Phillip

2017-11-01

A growing literature indicates that mitochondria are key participants in innate immune pathways, functioning as both signaling platforms and contributing to effector responses. In addition to regulating antiviral signaling and antibacterial immunity, mitochondria are also important drivers of inflammation caused by sterile injury. Much research on mitochondrial control of immunity now centers on understanding how mitochondrial constituents released during cellular damage simulate the innate immune system. When mitochondrial integrity is compromised, mitochondrial damage-associated molecular patterns engage pattern recognition receptors, trigger inflammation, and promote pathology in an expanding list of diseases. Here, I review the emerging knowledge of mitochondrial dysfunction in innate immune responses and discuss how environmental exposures may induce mitochondrial damage to potentiate inflammation and human disease. Copyright © 2017 Elsevier B.V. All rights reserved.

Triggering soft bombs at the LHC

DOE PAGES

Knapen, Simon; Griso, Simone Pagan; Papucci, Michele; ...

2017-08-18

Very high multiplicity, spherically-symmetric distributions of soft particles, with p T ~ few×100 MeV, may be a signature of strongly-coupled hidden valleys that exhibit long, efficient showering windows. With traditional triggers, such ‘soft bomb’ events closely resemble pile-up and are therefore only recorded with minimum bias triggers at a very low efficiency. We demonstrate a proof-of-concept for a high-level triggering strategy that efficiently separates soft bombs from pile-up by searching for a ‘belt of fire’: a high density band of hits on the innermost layer of the tracker. Seeding our proposed high-level trigger with existing jet, missing transverse energy ormore » lepton hardware-level triggers, we show that net trigger efficiencies of order 10% are possible for bombs of mass several × 100 GeV. We also consider the special case that soft bombs are the result of an exotic decay of the 125 GeV Higgs. The fiducial rate for ‘Higgs bombs’ triggered in this manner is marginally higher than the rate achievable by triggering directly on a hard muon from associated Higgs production.« less

Triggering soft bombs at the LHC

NASA Astrophysics Data System (ADS)

Knapen, Simon; Griso, Simone Pagan; Papucci, Michele; Robinson, Dean J.

2017-08-01

Very high multiplicity, spherically-symmetric distributions of soft particles, with p T ˜ few×100 MeV, may be a signature of strongly-coupled hidden valleys that exhibit long, efficient showering windows. With traditional triggers, such `soft bomb' events closely resemble pile-up and are therefore only recorded with minimum bias triggers at a very low efficiency. We demonstrate a proof-of-concept for a high-level triggering strategy that efficiently separates soft bombs from pile-up by searching for a `belt of fire': a high density band of hits on the innermost layer of the tracker. Seeding our proposed high-level trigger with existing jet, missing transverse energy or lepton hardware-level triggers, we show that net trigger efficiencies of order 10% are possible for bombs of mass several × 100 GeV. We also consider the special case that soft bombs are the result of an exotic decay of the 125 GeV Higgs. The fiducial rate for `Higgs bombs' triggered in this manner is marginally higher than the rate achievable by triggering directly on a hard muon from associated Higgs production.

Triggering soft bombs at the LHC

DOE Office of Scientific and Technical Information (OSTI.GOV)

Knapen, Simon; Griso, Simone Pagan; Papucci, Michele

Very high multiplicity, spherically-symmetric distributions of soft particles, with p T ~ few×100 MeV, may be a signature of strongly-coupled hidden valleys that exhibit long, efficient showering windows. With traditional triggers, such ‘soft bomb’ events closely resemble pile-up and are therefore only recorded with minimum bias triggers at a very low efficiency. We demonstrate a proof-of-concept for a high-level triggering strategy that efficiently separates soft bombs from pile-up by searching for a ‘belt of fire’: a high density band of hits on the innermost layer of the tracker. Seeding our proposed high-level trigger with existing jet, missing transverse energy ormore » lepton hardware-level triggers, we show that net trigger efficiencies of order 10% are possible for bombs of mass several × 100 GeV. We also consider the special case that soft bombs are the result of an exotic decay of the 125 GeV Higgs. The fiducial rate for ‘Higgs bombs’ triggered in this manner is marginally higher than the rate achievable by triggering directly on a hard muon from associated Higgs production.« less

Small beetle, large-scale drivers: how regional and landscape factors affect outbreaks of the European spruce bark beetle

PubMed Central

Seidl, Rupert; Müller, Jörg; Hothorn, Torsten; Bässler, Claus; Heurich, Marco; Kautz, Markus

2016-01-01

Summary 1. Unprecedented bark beetle outbreaks have been observed for a variety of forest ecosystems recently, and damage is expected to further intensify as a consequence of climate change. In Central Europe, the response of ecosystem management to increasing infestation risk has hitherto focused largely on the stand level, while the contingency of outbreak dynamics on large-scale drivers remains poorly understood. 2. To investigate how factors beyond the local scale contribute to the infestation risk from Ips typographus (Col., Scol.), we analysed drivers across seven orders of magnitude in scale (from 103 to 1010 m2) over a 23-year period, focusing on the Bavarian Forest National Park. Time-discrete hazard modelling was used to account for local factors and temporal dependencies. Subsequently, beta regression was applied to determine the influence of regional and landscape factors, the latter characterized by means of graph theory. 3. We found that in addition to stand variables, large-scale drivers also strongly influenced bark beetle infestation risk. Outbreak waves were closely related to landscape-scale connectedness of both host and beetle populations as well as to regional bark beetle infestation levels. Furthermore, regional summer drought was identified as an important trigger for infestation pulses. Large-scale synchrony and connectivity are thus key drivers of the recently observed bark beetle outbreak in the area. 4. Synthesis and applications. Our multiscale analysis provides evidence that the risk for biotic disturbances is highly dependent on drivers beyond the control of traditional stand-scale management. This finding highlights the importance of fostering the ability to cope with and recover from disturbance. It furthermore suggests that a stronger consideration of landscape and regional processes is needed to address changing disturbance regimes in ecosystem management. PMID:27041769

Review Of Existing Facilities: Shock Tunnels, Part of AIAA Short Course On Aerothermodynamic Facilities and Applications

NASA Technical Reports Server (NTRS)

Bogdanoff, David W.; Edwards, Thomas A. (Technical Monitor)

1995-01-01

This review is divided into two main sections. The first section described the various types of shock tunnel facilities - reflected shock tunnels, non-reflected shock tunnels and expansion tubes/tunnels. Driver technology is then described, followed by a discussion of the performance obtainable from various driver-driven combinations. A survey of a number of facilities is then presented. The second part of the review deals with details of the operation of the facilities. Operation of combustion drivers, electrically heated drivers and piston compression drivers is discussed in some detail. Main diaphragm break techniques are discussed, with particular attention being paid to maintaining the integrity of the diaphragm petals. Secondary diaphragm techniques are discussed. Phenomena which limit test time are discussed and a number of techniques to increase test time are presented. Contamination of the flow with material ablated from the wall is discussed along with the relative suitability of various materials for lining the tubes and nozzle. Finally, boundary layer effects in shock tunnels and expansion tubes are discussed.

EEG-based driver fatigue detection using hybrid deep generic model.

PubMed

Phyo Phyo San; Sai Ho Ling; Rifai Chai; Tran, Yvonne; Craig, Ashley; Hung Nguyen

2016-08-01

Classification of electroencephalography (EEG)-based application is one of the important process for biomedical engineering. Driver fatigue is a major case of traffic accidents worldwide and considered as a significant problem in recent decades. In this paper, a hybrid deep generic model (DGM)-based support vector machine is proposed for accurate detection of driver fatigue. Traditionally, a probabilistic DGM with deep architecture is quite good at learning invariant features, but it is not always optimal for classification due to its trainable parameters are in the middle layer. Alternatively, Support Vector Machine (SVM) itself is unable to learn complicated invariance, but produces good decision surface when applied to well-behaved features. Consolidating unsupervised high-level feature extraction techniques, DGM and SVM classification makes the integrated framework stronger and enhance mutually in feature extraction and classification. The experimental results showed that the proposed DBN-based driver fatigue monitoring system achieves better testing accuracy of 73.29 % with 91.10 % sensitivity and 55.48 % specificity. In short, the proposed hybrid DGM-based SVM is an effective method for the detection of driver fatigue in EEG.

A Simulation of the Front End Signal Digitization for the ATLAS Muon Spectrometer thin RPC trigger upgrade project

NASA Astrophysics Data System (ADS)

Meng, Xiangting; Chapman, John; Levin, Daniel; Dai, Tiesheng; Zhu, Junjie; Zhou, Bing; Um Atlas Group Team

2016-03-01

The ATLAS Muon Spectrometer Phase-I (and Phase-II) upgrade includes the BIS78 muon trigger detector project: two sets of eight very thin Resistive Place Chambers (tRPCs) combined with small Monitored Drift Tube (MDT) chambers in the pseudorapidity region 1<| η|<1.3. The tRPCs will be comprised of triplet readout layer in each of the eta and azimuthal phi coordinates, with about 400 readout strips per layer. The anticipated hit rate is 100-200 kHz per strip. Digitization of the strip signals will be done by 32-channel CERN HPTDC chips. The HPTDC is a highly configurable ASIC designed by the CERN Microelectronics group. It can work in both trigger and trigger-less modes, be readout in parallel or serially. For Phase-I operation, a stringent latency requirement of 43 bunch crossings (1075 ns) is imposed. The latency budget for the front end digitization must be kept to a minimal value, ideally less than 350 ns. We conducted detailed HPTDC latency simulations using the Behavioral Verilog code from the CERN group. We will report the results of these simulations run for the anticipated detector operating environment and for various HPTDC configurations.

Gyrotactic trapping: A numerical study

NASA Astrophysics Data System (ADS)

Ghorai, S.

2016-04-01

Gyrotactic trapping is a mechanism proposed by Durham et al. ["Disruption of vertical motility by shear triggers formation of thin Phytoplankton layers," Science 323, 1067-1070 (2009)] to explain the formation of thin phytoplankton layer just below the ocean surface. This mechanism is examined numerically using a rational model based on the generalized Taylor dispersion theory. The crucial role of sedimentation speed in the thin layer formation is demonstrated. The effects of variation in different parameters on the thin layer formation are also investigated.

Dynamically triggered slip leading to sustained fault gouge weakening under laboratory shear conditions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Paul Allan

We investigate dynamic wave-triggered slip under laboratory shear conditions. The experiment is composed of a three-block system containing two gouge layers composed of glass beads and held in place by a fixed load in a biaxial configuration. When the system is sheared under steady state conditions at a normal load of 4 MPa, we find that shear failure may be instantaneously triggered by a dynamic wave, corresponding to material weakening and softening if the system is in a critical shear stress state (near failure). Following triggering, the gouge material remains in a perturbed state over multiple slip cycles as evidencedmore » by the recovery of the material strength, shear modulus, and slip recurrence time. This work suggests that faults must be critically stressed to trigger under dynamic conditions and that the recovery process following a dynamically triggered event differs from the recovery following a spontaneous event.« less

Dynamically triggered slip leading to sustained fault gouge weakening under laboratory shear conditions

DOE PAGES

Johnson, Paul Allan

2016-02-28

We investigate dynamic wave-triggered slip under laboratory shear conditions. The experiment is composed of a three-block system containing two gouge layers composed of glass beads and held in place by a fixed load in a biaxial configuration. When the system is sheared under steady state conditions at a normal load of 4 MPa, we find that shear failure may be instantaneously triggered by a dynamic wave, corresponding to material weakening and softening if the system is in a critical shear stress state (near failure). Following triggering, the gouge material remains in a perturbed state over multiple slip cycles as evidencedmore » by the recovery of the material strength, shear modulus, and slip recurrence time. This work suggests that faults must be critically stressed to trigger under dynamic conditions and that the recovery process following a dynamically triggered event differs from the recovery following a spontaneous event.« less

Tsunamis warning from space :Ionosphere seismology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Larmat, Carene

2012-09-04

Ionosphere is the layer of the atmosphere from about 85 to 600km containing electrons and electrically charged atoms that are produced by solar radiation. Perturbations - layering affected by day and night, X-rays and high-energy protons from the solar flares, geomagnetic storms, lightning, drivers-from-below. Strategic for radio-wave transmission. This project discusses the inversion of ionosphere signals, tsunami wave amplitude and coupling parameters, which improves tsunami warning systems.

Tearing modes induced by perpendicular electron cyclotron resonance heating in the KSTAR tokamak

NASA Astrophysics Data System (ADS)

Lee, H. H.; Lee, S. G.; Seol, J.; Aydemir, A. Y.; Bae, C.; Yoo, J. W.; Na, Y. S.; Kim, H. S.; Woo, M. H.; Kim, J.; Joung, M.; You, K. I.; Park, B. H.

2014-10-01

This paper reports on experimental evidence that shows perpendicular electron cyclotron resonance heating (ECRH) can trigger classical tearing modes when deposited near a rational flux surface. The complex evolution of an m = 2 island is followed during current ramp-up in KSTAR plasmas, from its initial onset as the rational surface enters the ECRH resonance layer to its eventual lock on the wall after the rational surface leaves the layer. Stability analysis coupled to a transport calculation of the current profile with ECRH shows that the perpendicular ECRH may play a significant role in triggering and destabilizing classical m = 2 tearing modes, in agreement with our experimental observation.

Zombie Turbulence and More in Stratified Couette Flow

NASA Astrophysics Data System (ADS)

Marcus, Philip; Barranco, Joe; Pei, Suyang; Jiang, Chung-Hsiang

2016-11-01

Zombie turbulence occurs in rotating, shearing vertically-stratified flows such as stratified Couette flows. The turbulence is triggered by a neutrally-stable eigenmode with a critical layer receptive to finite-amplitude perturbations. Once excited, the critical layer becomes a vortex layer pair that rolls up into discrete vortices. Those vortices excite new critical layers, and the process repeats ad infinitum. When the vortex amplitudes become sufficiently large, the flow becomes turbulent. Although possessing a mid-range energy spectrum with E (k) k - 5 / 3 , the turbulence is non-Kolmogorov, highly anisotropic, and with large turbulent, but coherent, structures that retain the length scales of the spacing between the critical layers. The motivation for this study is protoplanetary disks (PPDs) where new stars form. In the PPD the Brunt-Vaisala frequency N increases as a function of distance from the midplane where it is zero. We cannot trigger the initial finite amplitude instability where N is small (close to the midplane). However, computations in PPDs and Couette flows show that zombie turbulence forms where N is large, and then a new type of turbulence, that is neither zombie nor Kolmogorov turbulence, fills in the remainder of the domain even where N = 0 .

Examining the influence of aggressive driving behavior on driver injury severity in traffic crashes.

PubMed

Paleti, Rajesh; Eluru, Naveen; Bhat, Chandra R

2010-11-01

In this paper, we capture the moderating effect of aggressive driving behavior while assessing the influence of a comprehensive set of variables on injury severity. In doing so, we are able to account for the indirect effects of variables on injury severity through their influence on aggressive driving behavior, as well as the direct effect of variables on injury severity. The methodology used in the paper to accommodate the moderating effect of aggressive driving behavior takes the form of two models--one for aggressive driving and another for injury severity. These are appropriately linked to obtain the indirect and direct effects of variables. The data for estimation is obtained from the National Motor Vehicle Crash Causation Study (NMVCCS). From an empirical standpoint, we consider a fine age categorization until 20 years of age when examining age effects on aggressive driving behavior and injury severity. There are several important results from the empirical analysis undertaken in the current paper based on post-crash data collection on aggressive behavior participation just prior to the crash and injury severity sustained in a crash. Young drivers (especially novice drivers between 16 and 17 years of age), drivers who are not wearing seat belt, under the influence of alcohol, not having a valid license, and driving a pick-up are found to be most likely to behave aggressively. Situational, vehicle, and roadway factors such as young drivers traveling with young passengers, young drivers driving an SUV or a pick-up truck, driving during the morning rush hour, and driving on roads with high speed limits are also found to trigger aggressive driving behavior. In terms of vehicle occupants, the safest situation from a driver injury standpoint is when there are two or more passengers in the vehicle, at least one of whom is above the age of 20 years. These and many other results are discussed, along with implications of the result for graduated driving licensing (GDL) programs. 2010 Elsevier Ltd. All rights reserved.

Ultrafast triggered transient energy storage by atomic layer deposition into porous silicon for integrated transient electronics

NASA Astrophysics Data System (ADS)

Douglas, Anna; Muralidharan, Nitin; Carter, Rachel; Share, Keith; Pint, Cary L.

2016-03-01

Here we demonstrate the first on-chip silicon-integrated rechargeable transient power source based on atomic layer deposition (ALD) coating of vanadium oxide (VOx) into porous silicon. A stable specific capacitance above 20 F g-1 is achieved until the device is triggered with alkaline solutions. Due to the rational design of the active VOx coating enabled by ALD, transience occurs through a rapid disabling step that occurs within seconds, followed by full dissolution of all active materials within 30 minutes of the initial trigger. This work demonstrates how engineered materials for energy storage can provide a basis for next-generation transient systems and highlights porous silicon as a versatile scaffold to integrate transient energy storage into transient electronics.Here we demonstrate the first on-chip silicon-integrated rechargeable transient power source based on atomic layer deposition (ALD) coating of vanadium oxide (VOx) into porous silicon. A stable specific capacitance above 20 F g-1 is achieved until the device is triggered with alkaline solutions. Due to the rational design of the active VOx coating enabled by ALD, transience occurs through a rapid disabling step that occurs within seconds, followed by full dissolution of all active materials within 30 minutes of the initial trigger. This work demonstrates how engineered materials for energy storage can provide a basis for next-generation transient systems and highlights porous silicon as a versatile scaffold to integrate transient energy storage into transient electronics. Electronic supplementary information (ESI) available: (i) Experimental details for ALD and material fabrication, ellipsometry film thickness, preparation of gel electrolyte and separator, details for electrochemical measurements, HRTEM image of VOx coated porous silicon, Raman spectroscopy for VOx as-deposited as well as annealed in air for 1 hour at 450 °C, SEM and transient behavior dissolution tests of uniformly coated VOx on porous silicon, dissolution tests for 0.1 M and 0.01 M NaOH trigger solutions, EIS analysis for VOx coated devices, and EDS compositional analysis of VOx. (ii) Video showing transient behavior of integrated VOx/porous silicon scaffolds. See DOI: 10.1039/c5nr09095d

Creating pedestrian crash scenarios in a driving simulator environment.

PubMed

Chrysler, Susan T; Ahmad, Omar; Schwarz, Chris W

2015-01-01

In 2012 in the United States, pedestrian injuries accounted for 3.3% of all traffic injuries but, disproportionately, pedestrian fatalities accounted for roughly 14% of traffic-related deaths (NHTSA 2014 ). In many other countries, pedestrians make up more than 50% of those injured and killed in crashes. This research project examined driver response to crash-imminent situations involving pedestrians in a high-fidelity, full-motion driving simulator. This article presents a scenario development method and discusses experimental design and control issues in conducting pedestrian crash research in a simulation environment. Driving simulators offer a safe environment in which to test driver response and offer the advantage of having virtual pedestrian models that move realistically, unlike test track studies, which by nature must use pedestrian dummies on some moving track. An analysis of pedestrian crash trajectories, speeds, roadside features, and pedestrian behavior was used to create 18 unique crash scenarios representative of the most frequent and most costly crash types. For the study reported here, we only considered scenarios where the car is traveling straight because these represent the majority of fatalities. We manipulated driver expectation of a pedestrian both by presenting intersection and mid-block crossing as well as by using features in the scene to direct the driver's visual attention toward or away from the crossing pedestrian. Three visual environments for the scenarios were used to provide a variety of roadside environments and speed: a 20-30 mph residential area, a 55 mph rural undivided highway, and a 40 mph urban area. Many variables of crash situations were considered in selecting and developing the scenarios, including vehicle and pedestrian movements; roadway and roadside features; environmental conditions; and characteristics of the pedestrian, driver, and vehicle. The driving simulator scenarios were subjected to iterative testing to adjust time to arrival triggers for the pedestrian actions. This article discusses the rationale behind creating the simulator scenarios and some of the procedural considerations for conducting this type of research. Crash analyses can be used to construct test scenarios for driver behavior evaluations using driving simulators. By considering trajectories, roadway, and environmental conditions of real-world crashes, representative virtual scenarios can serve as safe test beds for advanced driver assistance systems. The results of such research can be used to inform pedestrian crash avoidance/mitigation systems by identifying driver error, driver response time, and driver response choice (i.e., steering vs. braking).

GPU-based low-level trigger system for the standalone reconstruction of the ring-shaped hit patterns in the RICH Cherenkov detector of NA62 experiment

NASA Astrophysics Data System (ADS)

Ammendola, R.; Biagioni, A.; Chiozzi, S.; Cretaro, P.; Cotta Ramusino, A.; Di Lorenzo, S.; Fantechi, R.; Fiorini, M.; Frezza, O.; Gianoli, A.; Lamanna, G.; Lo Cicero, F.; Lonardo, A.; Martinelli, M.; Neri, I.; Paolucci, P. S.; Pastorelli, E.; Piandani, R.; Piccini, M.; Pontisso, L.; Rossetti, D.; Simula, F.; Sozzi, M.; Vicini, P.

2017-03-01

This project aims to exploit the parallel computing power of a commercial Graphics Processing Unit (GPU) to implement fast pattern matching in the Ring Imaging Cherenkov (RICH) detector for the level 0 (L0) trigger of the NA62 experiment. In this approach, the ring-fitting algorithm is seedless, being fed with raw RICH data, with no previous information on the ring position from other detectors. Moreover, since the L0 trigger is provided with a more elaborated information than a simple multiplicity number, it results in a higher selection power. Two methods have been studied in order to reduce the data transfer latency from the readout boards of the detector to the GPU, i.e., the use of a dedicated NIC device driver with very low latency and a direct data transfer protocol from a custom FPGA-based NIC to the GPU. The performance of the system, developed through the FPGA approach, for multi-ring Cherenkov online reconstruction obtained during the NA62 physics runs is presented.

Drivers of atmospheric evaporative demand during African droughts

NASA Astrophysics Data System (ADS)

Blakeley, S. L.; Harrison, L.; Hobbins, M.; Dewes, C.; Funk, C. C.; Shukla, S.; Husak, G. J.

2017-12-01

Seeking to advance the practice of famine early warning across sub-Saharan Africa we illuminate past drivers of high-impact droughts to gain a better understanding of the evaporative processes involved in drought dynamics. Atmospheric evaporative demand (ETo) is often used to estimate plant water balance and drought impacts to vegetation, and previously demonstrated linkages between precipitation, temperature, and ETo need to be better understood. This work is timely as new data streams will enable near-real-time monitoring of ETo and incorporation of ETo forecasts into seasonal outlooks for African growing seasons. For historical droughts during major growing seasons in sub-Saharan Africa, we evaluate ETo and identify main drivers for drought cases-identified based on below-normal precipitation during the wettest three months of the growing season-and contrast these with the ETo drivers that dominate in wetter years (we also consider droughts triggered by above normal ETo). Our focus is on regions of Africa where adequate precipitation is important for productive agriculture and pastoral activities and where evaporative demand might exacerbate moisture limitations. It is expected that important ETo drivers are partly connected with precipitation-related processes but that there are variations between regions and events. The goal here is to provide a generalized understanding of what aspects of evaporative demand historically have posed an additional hazard to plant stress and how precipitation outcomes are responsible for the ETo drivers. In addition, we explore whether there have been discernible changes through time in regard to ETo drivers during below-normal precipitation seasons. Upper and lower terciles of CHIRPS precipitation are used to identify anomalous dry and wet cases. The ETo dataset spans the 1980-near present period and is calculated following ASCE's formulation of Penman-Monteith method driven by daily temperature, humidity, wind speed, and solar radiation from NASA's MERRA-2; this data is the basis for the Evaporative Demand Drought Index (EDDI). ETo drivers are identified with the decomposition method from Hobbins et al. (2016), which considers the anomalies in meteorological variables and the sensitivity of ETo to each of them.

Remote direct memory access over datagrams

DOEpatents

Grant, Ryan Eric; Rashti, Mohammad Javad; Balaji, Pavan; Afsahi, Ahmad

2014-12-02

A communication stack for providing remote direct memory access (RDMA) over a datagram network is disclosed. The communication stack has a user level interface configured to accept datagram related input and communicate with an RDMA enabled network interface card (NIC) via an NIC driver. The communication stack also has an RDMA protocol layer configured to supply one or more data transfer primitives for the datagram related input of the user level. The communication stack further has a direct data placement (DDP) layer configured to transfer the datagram related input from a user storage to a transport layer based on the one or more data transfer primitives by way of a lower layer protocol (LLP) over the datagram network.

Target-molecule-triggered rupture of aptamer-encapsulated polyelectrolyte microcapsules.

PubMed

Zhang, Xueru; Chabot, Denise; Sultan, Yasir; Monreal, Carlos; DeRosa, Maria C

2013-06-26

Polyelectrolyte microcapsules have great potential for serving as carriers for the delivery of their contents when triggered by an external stimulus. Aptamers are synthetic ssDNA or RNA that can bind to specific targets with high affinity and selectivity. Aptamers may retain these superior molecular recognition properties after encapsulation within polymer microcapsules. In this work, stable polyelectrolyte microcapsules with encapsulated aptamers were obtained by the layer-by-layer (LbL) method. Polyelectrolyte films were deposited onto a CaCO3 template that had been predoped with polystyrene sulfonate (PSS) and aptamer sequences (SA) that have an affinity for the dye sulforhodamine B (SRB). The PSS and aptamers are thought to serve as an internal scaffold supporting the microcapsule walls. These microcapsules would present target-molecule-triggered rupture properties. Microcapsule collapse was triggered by the binding of SRB to the encapsulated aptamer. The specificity of microcapsule collapse was investigated using a similar dye, tetramethylrosamine (TMR), which does not have affinity for SA. A high concentration of TMR did not lead to the collapse of the microcapsules. The effect of target binding on the microcapsules was confirmed by scanning electron microscopy (SEM) and confocal laser scanning microscopy (CLSM). These microcapsules may have potential applications in targeted delivery systems for the controlled release of drugs, pesticides, or other payloads.

Driver Behavior During Overtaking Maneuvers from the 100-Car Naturalistic Driving Study.

PubMed

Chen, Rong; Kusano, Kristofer D; Gabler, Hampton C

2015-01-01

Lane changes with the intention to overtake the vehicle in front are especially challenging scenarios for forward collision warning (FCW) designs. These overtaking maneuvers can occur at high relative vehicle speeds and often involve no brake and/or turn signal application. Therefore, overtaking presents the potential of erroneously triggering the FCW. A better understanding of driver behavior during lane change events can improve designs of this human-machine interface and increase driver acceptance of FCW. The objective of this study was to aid FCW design by characterizing driver behavior during lane change events using naturalistic driving study data. The analysis was based on data from the 100-Car Naturalistic Driving Study, collected by the Virginia Tech Transportation Institute. The 100-Car study contains approximately 1.2 million vehicle miles of driving and 43,000 h of data collected from 108 primary drivers. In order to identify overtaking maneuvers from a large sample of driving data, an algorithm to automatically identify overtaking events was developed. The lead vehicle and minimum time to collision (TTC) at the start of lane change events was identified using radar processing techniques developed in a previous study. The lane change identification algorithm was validated against video analysis, which manually identified 1,425 lane change events from approximately 126 full trips. Forty-five drivers with valid time series data were selected from the 100-Car study. From the sample of drivers, our algorithm identified 326,238 lane change events. A total of 90,639 lane change events were found to involve a closing lead vehicle. Lane change events were evenly distributed between left side and right side lane changes. The characterization of lane change frequency and minimum TTC was divided into 10 mph speed bins for vehicle travel speeds between 10 and 90 mph. For all lane change events with a closing lead vehicle, the results showed that drivers change lanes most frequently in the 40-50 mph speed range. Minimum TTC was found to increase with travel speed. The variability in minimum TTC between drivers also increased with travel speed. This study developed and validated an algorithm to detect lane change events in the 100-Car Naturalistic Driving Study and characterized lane change events in the database. The characterization of driver behavior in lane change events showed that driver lane change frequency and minimum TTC vary with travel speed. The characterization of overtaking maneuvers from this study will aid in improving the overall effectiveness of FCW systems by providing active safety system designers with further understanding of driver action in overtaking maneuvers, thereby increasing system warning accuracy, reducing erroneous warnings, and improving driver acceptance.

An International Comparative Study on Driving Regulations on People with Dementia.

PubMed

Kim, You Joung; An, Hoyoung; Kim, Binna; Park, Young Shin; Kim, Ki Woong

2017-01-01

Over 40% of people with dementia drive, with a two to five times greater accident risk than controls. This has fueled public concerns about the risk of traffic accidents by drivers with dementia (DWD). We compared driving regulations on seniors and DWD between ten European and Asia-Pacific countries to identify key implications for national strategies. Moderate to severe dementia was a reason for driver's license revocation in all countries. However, regulations on mild dementia varied considerably, with most basing their decisions on severity, rather than simply the presence of dementia. Most used validated assessments, but responsibility for triggering the administrative process fell on drivers in some countries and on physicians in others. Administrations should consider the following when developing driving policies: 1) ideal regulations on DWD should ensure that restrictions are implemented only when needed; 2) fitness to drive should be assessed using validated instruments; 3) the use of processes that automatically initiate driving competency examinations following a diagnosis of dementia should be explored; and 4) restrictions should be delicately tailored to a range of driving competence levels, and assistive incentives compensating for lost driving privileges should be provided.

Meteorological variables associated with deep slab avalanches on persistent weak layers

USGS Publications Warehouse

Marienthal, Alex; Hendrikx, Jordy; Birkeland, Karl; Irvine, Kathryn M.

2014-01-01

Deep slab avalanches are a particularly challenging avalanche forecasting problem. These avalanches are typically difficult to trigger, yet when they are triggered they tend to propagate far and result in large and destructive avalanches. For this work we define deep slab avalanches as those that fail on persistent weak layers deeper than 0.9m (3 feet), and that occur after February 1st. We utilized a 44-year record of avalanche control and meteorological data from Bridger Bowl Ski Area to test the usefulness of meteorological variables for predicting deep slab avalanches. As in previous studies, we used data from the days preceding deep slab cycles, but we also considered meteorological metrics over the early months of the season. We utilized classification trees for our analyses. Our results showed warmer temperatures in the prior twenty-four hours and more loading over the seven days before days with deep slab avalanches on persistent weak layers. In line with previous research, extended periods of above freezing temperatures led to days with deep wet slab avalanches on persistent weak layers. Seasons with either dry or wet avalanches on deep persistent weak layers typically had drier early months, and often had some significant snow depth prior to those dry months. This paper provides insights for ski patrollers, guides, and avalanche forecasters who struggle to forecast deep slab avalanches on persistent weak layers late in the season.

A trial of retrofitted advisory collision avoidance technology in government fleet vehicles.

PubMed

Thompson, James P; Mackenzie, Jamie R R; Dutschke, Jeffrey K; Baldock, Matthew R J; Raftery, Simon J; Wall, John

2018-06-01

In-vehicle collision avoidance technology (CAT) has the potential to prevent crash involvement. In 2015, Transport for New South Wales undertook a trial of a Mobileye 560 CAT system that was installed in 34 government fleet vehicles for a period of seven months. The system provided headway monitoring, lane departure, forward collision and pedestrian collision warnings, using audio and visual alerts. The purpose of the trial was to determine whether the technology could change the driving behaviour of fleet vehicle drivers and improve their safety. The evaluation consisted of three components: (1) analysis of objective data to examine effects of the technology on driving behaviour, (2) analysis of video footage taken from a sample of the vehicles to examine driving circumstances that trigger headway monitoring and forward collision warnings, and (3) a survey completed by 122 of the 199 individuals who drove the trial vehicles to examine experiences with, and attitudes to, the technology. Analysis of the objective data found that the system resulted in changes in behaviour with increased headway and improved lane keeping, but that these improvements dissipated once the warning alerts were switched off. Therefore, the system is capable of altering behaviour but only when it is actively providing alerts. In-vehicle video footage revealed that over a quarter of forward collision warnings were false alarms, in which a warning event was triggered despite there being no vehicle travelling ahead. The surveyed drivers recognised that the system could improve safety but most did not wish to use it themselves as they found it to be distracting and felt that it would not prevent them from having a crash. The results demonstrate that collision avoidance technology can improve driving behaviour but drivers may need to be educated about the potential benefits for their driving in order to accept the technology. Copyright © 2018 Elsevier Ltd. All rights reserved.

LES on Plume Dispersion in the Convective Boundary Layer Capped by a Temperature Inversion

NASA Astrophysics Data System (ADS)

Nakayama, Hiromasa; Tamura, Tetsuro; Abe, Satoshi

Large-eddy simulation (LES) is applied to the problem of plume dispersion in the spatially-developing convective boundary layer (CBL) capped by a temperature inversion. In order to generate inflow turbulence with buoyant forcing, we first, simulate the neutral boundary layer flow (NBL) in the driver region using Lund's method. At the same time, the temperature profile possessing the inversion part is imposed at the entrance of the driver region and the temperature field is calculated as a passive scalar. Next, the buoyancy effect is introduced into the flow field in the main region. We evaluate the applicability of the LES model for atmospheric dispersion in the CBL flow and compare the characteristics of plume dispersion in the CBL flow with those in the neutral boundary layer. The Richardson number based on the temperature increment across the inversion obtained by the present LES model is 22.4 and the capping effect of the temperature inversion can be captured qualitatively in the upper portion of the CBL. Characteristics of flow and temperature fields in the main portion of CBL flow are similar to those of previous experiments[1],[2] and observations[3]. Concerning dispersion behavior, we also find that mean concentrations decrease immediately above the inversion height and the peak values of r.m.s concentrations are located near the inversion height at larger distances from the point source.

Evidence for remotely triggered micro-earthquakes during salt cavern collapse

NASA Astrophysics Data System (ADS)

Jousset, P.; Rohmer, J.

2012-04-01

Micro-seismicity is a good indicator of spatio-temporal evolution of physical properties of rocks prior to catastrophic events like volcanic eruptions or landslides and may be triggered by a number of causes including dynamic characteristics of processes in play or/and external forces. Micro-earthquake triggering has been in the recent years the subject of intense research and our work contribute to showing further evidence of possible triggering of micro-earthquakes by remote large earthquakes. We show evidence of triggered micro-seismicity in the vicinity of an underground salt cavern prone to collapse by a remote M~7.2 earthquake, which occurred ~12000 kilometres away. We demonstrate the near critical state of the cavern before the collapse by means of 2D axisymmetric elastic finite-element simulations. Pressure was lowered in the cavern by pumping operations of brine out of the cavern. We demonstrate that a very small stress increase would be sufficient to break the overburden. High-dynamic broadband records reveal a remarkable time-correlation between a dramatic increase of the local high-frequency micro-seismicity rate associated with the break of the stiffest layer stabilizing the overburden and the passage of low-frequency remote seismic waves, including body, Love and Rayleigh surface waves. Stress oscillations due to the seismic waves exceeded the strength required for the rupture of the complex media made of brine and rock triggering micro-earthquakes and leading to damage of the overburden and eventually collapse of the salt cavern. The increment of stress necessary for the failure of a Dolomite layer is of the same order or magnitude as the maximum dynamic stress magnitude observed during the passage of the earthquakes waves. On this basis, we discuss the possible contribution of the Love and Rayleigh low-frequency surfaces waves.

Numerical simulation of strong wake/boundary layer interaction

NASA Astrophysics Data System (ADS)

Ovchinnikov, Victor; Piomelli, Ugo; Choudhari, Meelan M.

2003-11-01

DNS and LES of the strong interaction between an unsteady cylinder wake and a flat-plate boundary layer are carried out. Of the two Reynolds numbers examined, in the lower Reynolds number case (Re=385 based on cylinder diameter) the boundary layer is buffeted by the vortices shed off the cylinder, but the Reynolds number is too low to trigger transition to turbulence. In contrast, in the higher Reyolds number case (Re=1155) we observe the inception of a self-sustained turbulence-generation mechanism triggered by the Karman vortex street behind the cylinder. In previously performed simulations the computational box was not long enough to extend into the turbulent region; therefore, we have lengthened the streamwise domain using a second computational box in order to capture the transition point. In addition to examining turbulence statistics, we look at the Reynolds stress budgets up to and through the transitional regime to obtain further insights into the physics of bypass transition via wake contamination.

The CMS Level-1 Calorimeter Trigger for LHC Run II

NASA Astrophysics Data System (ADS)

Sinthuprasith, Tutanon

2017-01-01

The phase-1 upgrades of the CMS Level-1 calorimeter trigger have been completed. The Level-1 trigger has been fully commissioned and it will be used by CMS to collect data starting from the 2016 data run. The new trigger has been designed to improve the performance at high luminosity and large number of simultaneous inelastic collisions per crossing (pile-up). For this purpose it uses a novel design, the Time Multiplexed Design, which enables the data from an event to be processed by a single trigger processor at full granularity over several bunch crossings. The TMT design is a modular design based on the uTCA standard. The architecture is flexible and the number of trigger processors can be expanded according to the physics needs of CMS. Intelligent, more complex, and innovative algorithms are now the core of the first decision layer of CMS: the upgraded trigger system implements pattern recognition and MVA (Boosted Decision Tree) regression techniques in the trigger processors for pT assignment, pile up subtraction, and isolation requirements for electrons, and taus. The performance of the TMT design and the latency measurements and the algorithm performance which has been measured using data is also presented here.

Investigating land-atmosphere coupling and convective triggering associated with the moistening of the northern North American Great Plains

NASA Astrophysics Data System (ADS)

Gerken, Tobias; Bromley, Gabriel; Stoy, Paul

2017-04-01

Parts of the North American northern Great Plains have undergone a 6 W m-2 decrease in summertime radiative forcing. At the same time agricultural practices have shifted from keeping fields fallow during the summer ("summer fallow") towards no-till cropping systems that increase summertime evapotranspiration and decrease soil carbon loss. MERRA (Modern-Era Retrospective analysis for Research and Applications) for the area near Fort Peck, Montana, (a FLUXNET site established in 2000) shows a decrease of summertime (June-August) sensible heat fluxes ranging from -3.6 to -8.5 W m-2 decade-1, which is associated with an increase of latent heat fluxes of similar magnitude (5.2-9.1 W m-2 decade-1). While net radiation changed little, increasing downward longwave radiation (2.2-4.6 W m-2 decade-1) due to greater cloud cover, was mostly compensated by reduced solar irradiance. The result was a strong decrease of summer Bowen ratios from 1.5-2 in 1980 to approximately 1-1.25 in 2015. At the same time, atmospheric soundings have shown significant increases in both convective available convective energy (CAPE) and convective inhibition (CIN) for the same time span. Overall, these findings are consistent with the effects on increased summertime evapotranspiration due to reduction in summer fallow that should lead to smaller Bowen ratios and a larger build-up of moist static energy as expressed in higher values of CAPE. In order to further investigate the impact of the surface energy balance and flux partitioning on convective development and local land-atmosphere coupling in the North American prairies, a 1-dimensional mixed-layer model is used to compare the evolution of mixed-layer heights to the lifted condensation level, a necessary but not sufficient condition for the occurrence of convective precipitation. Using summertime eddy covariance data from Fort Peck and atmospheric soundings from the nearby Glasgow airport, we establish that the mixed-layer model adequately captures mixed-layer heights and timing of locally triggered convection at the site. The model is then used to quantify the sensitivity of mixing-layer height, CAPE and convective triggering potential, in response to changes in surface flux partitioning between latent and sensible heat due to changes in soil moisture and agricultural management. Results are used to establish the exact nature or land-atmosphere coupling associated with moistening of the atmospheric boundary-layer and increases in convective triggering and will contribute to disentangling local and regional effects on trends in observed precipitation in the northern Great Plains.

Observation of the L-H confinement bifurcation triggered by a turbulence-driven shear flow in a tokamak plasma.

PubMed

Yan, Z; McKee, G R; Fonck, R; Gohil, P; Groebner, R J; Osborne, T H

2014-03-28

Comprehensive 2D turbulence and eddy flow velocity measurements on DIII-D demonstrate a rapidly increasing turbulence-driven shear flow that develops ∼100  μs prior to the low-confinement (L mode) to high-confinement (H mode) transition and appears to trigger it. These changes are localized to a narrow layer 1-2 cm inside the magnetic boundary. Increasing heating power increases the Reynolds stress, the energy transfer from turbulence to the poloidal flow, and the edge flow shearing rate that then exceeds the decorrelation rate, suppressing turbulence and triggering the transition.

Fundamental studies on initiation and evolution of multi-channel discharges and their application to next generation pulsed power machines.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schwarz, Jens; Savage, Mark E.; Lucero, Diego Jose

Future pulsed power systems may rely on linear transformer driver (LTD) technology. The LTD's will be the building blocks for a driver that can deliver higher current than the Z-Machine. The LTD's would require tens of thousands of low inductance ( %3C 85nH), high voltage (200 kV DC) switches with high reliability and long lifetime ( 10 4 shots). Sandia's Z-Machine employs 36 megavolt class switches that are laser triggered by a single channel discharge. This is feasible for tens of switches but the high inductance and short switch life- time associated with the single channel discharge are undesirable formore » future machines. Thus the fundamental problem is how to lower inductance and losses while increasing switch life- time and reliability. These goals can be achieved by increasing the number of current-carrying channels. The rail gap switch is ideal for this purpose. Although those switches have been extensively studied during the past decades, each effort has only characterized a particular switch. There is no comprehensive understanding of the underlying physics that would allow predictive capability for arbitrary switch geometry. We have studied rail gap switches via an extensive suite of advanced diagnostics in synergy with theoretical physics and advanced modeling capability. Design and topology of multichannel switches as they relate to discharge dynamics are investigated. This involves electrically and optically triggered rail gaps, as well as discrete multi-site switch concepts.« less

Driving behavior recognition using EEG data from a simulated car-following experiment.

PubMed

Yang, Liu; Ma, Rui; Zhang, H Michael; Guan, Wei; Jiang, Shixiong

2018-07-01

Driving behavior recognition is the foundation of driver assistance systems, with potential applications in automated driving systems. Most prevailing studies have used subjective questionnaire data and objective driving data to classify driving behaviors, while few studies have used physiological signals such as electroencephalography (EEG) to gather data. To bridge this gap, this paper proposes a two-layer learning method for driving behavior recognition using EEG data. A simulated car-following driving experiment was designed and conducted to simultaneously collect data on the driving behaviors and EEG data of drivers. The proposed learning method consists of two layers. In Layer I, two-dimensional driving behavior features representing driving style and stability were selected and extracted from raw driving behavior data using K-means and support vector machine recursive feature elimination. Five groups of driving behaviors were classified based on these two-dimensional driving behavior features. In Layer II, the classification results from Layer I were utilized as inputs to generate a k-Nearest-Neighbor classifier identifying driving behavior groups using EEG data. Using independent component analysis, a fast Fourier transformation, and linear discriminant analysis sequentially, the raw EEG signals were processed to extract two core EEG features. Classifier performance was enhanced using the adaptive synthetic sampling approach. A leave-one-subject-out cross validation was conducted. The results showed that the average classification accuracy for all tested traffic states was 69.5% and the highest accuracy reached 83.5%, suggesting a significant correlation between EEG patterns and car-following behavior. Copyright © 2017 Elsevier Ltd. All rights reserved.

EzyAmp signal amplification cascade enables isothermal detection of nucleic acid and protein targets.

PubMed

Linardy, Evelyn M; Erskine, Simon M; Lima, Nicole E; Lonergan, Tina; Mokany, Elisa; Todd, Alison V

2016-01-15

Advancements in molecular biology have improved the ability to characterize disease-related nucleic acids and proteins. Recently, there has been an increasing desire for tests that can be performed outside of centralised laboratories. This study describes a novel isothermal signal amplification cascade called EzyAmp (enzymatic signal amplification) that is being developed for detection of targets at the point of care. EzyAmp exploits the ability of some restriction endonucleases to cleave substrates containing nicks within their recognition sites. EzyAmp uses two oligonucleotide duplexes (partial complexes 1 and 2) which are initially cleavage-resistant as they lack a complete recognition site. The recognition site of partial complex 1 can be completed by hybridization of a triggering oligonucleotide (Driver Fragment 1) that is generated by a target-specific initiation event. Binding of Driver Fragment 1 generates a completed complex 1, which upon cleavage, releases Driver Fragment 2. In turn, binding of Driver Fragment 2 to partial complex 2 creates completed complex 2 which when cleaved releases additional Driver Fragment 1. Each cleavage event separates fluorophore quencher pairs resulting in an increase in fluorescence. At this stage a cascade of signal production becomes independent of further target-specific initiation events. This study demonstrated that the EzyAmp cascade can facilitate detection and quantification of nucleic acid targets with sensitivity down to aM concentration. Further, the same cascade detected VEGF protein with a sensitivity of 20nM showing that this universal method for amplifying signal may be linked to the detection of different types of analytes in an isothermal format. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

High throughput CIGS solar cell fabrication via ultra-thin absorber layer with optical confinement and (Cd, CBD)-free heterojunction partner

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marsillac, Sylvain

2015-11-30

The main objective of this proposal was to use several pathways to reduce the production cost of Cu(In,Ga)Se 2 (CIGS) PV modules and therefore the levelized cost of energy (LCOE) associated with this technology. Three high cost drivers were identified, nominally: 1) Materials cost and availability; 2) Large scale uniformity; 3) Improved throughput These three cost drivers were targeted using the following pathways: 1) Reducing the thickness of the CIGS layer while enhancing materials quality; 2) Developing and applying enhanced in-situ metrology via real time spectroscopic ellipsometry; 3) Looking into alternative heterojunction partner, back contact and anti-reflection (AR) coating Elevenmore » main Tasks were then defined to achieve these goals (5 in Phase 1 and 6 in Phase 2), with 11 Milestones and 2 Go/No-go decision points at the end of Phase 1. The key results are summarized below« less

Transformative environmental governance

USGS Publications Warehouse

Chaffin, Brian C.; Garmestani, Ahjond S.; Gunderson, Lance H.; Harm Benson, Melinda; Angeler, David G.; Arnold, Craig Anthony (Tony); Cosens, Barbara; Kundis Craig, Robin; Ruhl, J.B.; Allen, Craig R.

2016-01-01

Transformative governance is an approach to environmental governance that has the capacity to respond to, manage, and trigger regime shifts in coupled social-ecological systems (SESs) at multiple scales. The goal of transformative governance is to actively shift degraded SESs to alternative, more desirable, or more functional regimes by altering the structures and processes that define the system. Transformative governance is rooted in ecological theories to explain cross-scale dynamics in complex systems, as well as social theories of change, innovation, and technological transformation. Similar to adaptive governance, transformative governance involves a broad set of governance components, but requires additional capacity to foster new social-ecological regimes including increased risk tolerance, significant systemic investment, and restructured economies and power relations. Transformative governance has the potential to actively respond to regime shifts triggered by climate change, and thus future research should focus on identifying system drivers and leading indicators associated with social-ecological thresholds.

Drivers of Environmental Institutional Dynamics in Decentralized African Countries.

PubMed

Hassenforder, Emeline; Barreteau, Olivier; Daniell, Katherine Anne; Pittock, Jamie; Ferrand, Nils

2015-12-01

This paper builds on the assumption that an effective approach to support the sustainability of natural resource management initiatives is institutional "bricolage." We argue that participatory planning processes can foster institutional bricolage by encouraging stakeholders to make their own arrangements based on the hybridization of old and new institutions. This papers aims at identifying how participatory process facilitators can encourage institutional bricolage. Specifically the paper investigates the specific contextual and procedural drivers of institutional dynamics in two case studies: the Rwenzori region in Uganda and the Fogera woreda in Ethiopia. In both cases, participatory planning processes were implemented. This research has three innovative aspects. First, it establishes a clear distinction between six terms which are useful for identifying, describing, and analyzing institutional dynamics: formal and informal; institutions and organizations; and emergence and change. Secondly, it compares the contrasting institutional dynamics in the two case studies. Thirdly, process-tracing is used to identify contextual and procedural drivers to institutional dynamics. We assume that procedural drivers can be used as "levers" by facilitators to trigger institutional bricolage. We found that facilitators need to pay particular attention to the institutional context in which the participatory planning process takes place, and especially at existing institutional gaps or failures. We identified three clusters of procedural levers: the selection and engagement of participants; the legitimacy, knowledge, and ideas of facilitators; and the design of the process, including the scale at which it is developed, the participatory tools used and the management of the diversity of frames.

Drivers of Environmental Institutional Dynamics in Decentralized African Countries

NASA Astrophysics Data System (ADS)

Hassenforder, Emeline; Barreteau, Olivier; Daniell, Katherine Anne; Pittock, Jamie; Ferrand, Nils

2015-12-01

This paper builds on the assumption that an effective approach to support the sustainability of natural resource management initiatives is institutional "bricolage." We argue that participatory planning processes can foster institutional bricolage by encouraging stakeholders to make their own arrangements based on the hybridization of old and new institutions. This papers aims at identifying how participatory process facilitators can encourage institutional bricolage. Specifically the paper investigates the specific contextual and procedural drivers of institutional dynamics in two case studies: the Rwenzori region in Uganda and the Fogera woreda in Ethiopia. In both cases, participatory planning processes were implemented. This research has three innovative aspects. First, it establishes a clear distinction between six terms which are useful for identifying, describing, and analyzing institutional dynamics: formal and informal; institutions and organizations; and emergence and change. Secondly, it compares the contrasting institutional dynamics in the two case studies. Thirdly, process-tracing is used to identify contextual and procedural drivers to institutional dynamics. We assume that procedural drivers can be used as "levers" by facilitators to trigger institutional bricolage. We found that facilitators need to pay particular attention to the institutional context in which the participatory planning process takes place, and especially at existing institutional gaps or failures. We identified three clusters of procedural levers: the selection and engagement of participants; the legitimacy, knowledge, and ideas of facilitators; and the design of the process, including the scale at which it is developed, the participatory tools used and the management of the diversity of frames.

Patterns and drivers of bacterial α- and β-diversity across vertical profiles from surface to subsurface sediments.

PubMed

Luna, Gian Marco; Corinaldesi, Cinzia; Rastelli, Eugenio; Danovaro, Roberto

2013-10-01

We investigated the patterns and drivers of bacterial α- and β-diversity, along with viral and prokaryotic abundance and the carbon production rates, in marine surface and subsurface sediments (down to 1 m depth) in two habitats: vegetated sediments (seagrass meadow) and non-vegetated sediments. Prokaryotic abundance and production decreased with depth in the sediment, but cell-specific production rates and the virus-to-prokaryote ratio increased, highlighting unexpectedly high activity in the subsurface. The highest diversity was observed in vegetated sediments. Bacterial β-diversity between sediment horizons was high, and only a minor number of taxa was shared between surface and subsurface layers. Viruses significantly contributed to explain α- and β-diversity patterns. Despite potential limitations due to the only use of fingerprinting techniques, this study indicates that the coastal subsurface host highly active and diversified bacterial assemblages, that subsurface cells are more active than expected and that viruses promote β-diversity and stimulate bacterial metabolism in subsurface layers. The limited number of taxa shared between habitats, and between surface and subsurface sediment horizons, suggests that future investigations of the shallow subsurface will provide insights into the census of bacterial diversity, and the comprehension of the patterns and drivers of prokaryotic diversity in marine ecosystems. © 2013 John Wiley & Sons Ltd and Society for Applied Microbiology.

Stability of Boundary Layer Flow.

DTIC Science & Technology

1980-03-01

climato- logical frequency of convection in the North Atlantic, and offered recom- U mendations on the modelling of triggered convection. The current ...support of the current investigation we have carried out several additional calculations of the marine boundary layer with SIGMET. These calculations...In a fixed coordinate system x ( positive eastward), y ( positive northward), and z ( positive vertically upward) the equations are au .U +vE + W+-U

Disruption of vertical motility by shear triggers formation of thin phytoplankton layers.

PubMed

Durham, William M; Kessler, John O; Stocker, Roman

2009-02-20

Thin layers of phytoplankton are important hotspots of ecological activity that are found in the coastal ocean, meters beneath the surface, and contain cell concentrations up to two orders of magnitude above ambient concentrations. Current interpretations of their formation favor abiotic processes, yet many phytoplankton species found in these layers are motile. We demonstrated that layers formed when the vertical migration of phytoplankton was disrupted by hydrodynamic shear. This mechanism, which we call gyrotactic trapping, can be responsible for the thin layers of phytoplankton commonly observed in the ocean. These results reveal that the coupling between active microorganism motility and ambient fluid motion can shape the macroscopic features of the marine ecological landscape.

The trigger and data acquisition for the NEMO-Phase 2 tower

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pellegrino, C.; Biagi, S.; Fusco, L. A.

In the framework of the Phase 2 of the NEMO neutrino telescope project, a tower with 32 optical modules is being operated since march 2013. A new scalable Trigger and Data Acquisition System (TriDAS) has been developed and extensively tested with the data from this tower. Adopting the all-data-to-shore concept, the NEMO TriDAS is optimized to deal with a continuous data-stream from off-shore to on-shore with a large bandwidth. The TriDAS consists of four computing layers: (i) data aggregation of isochronal hits from all optical modules; (ii) data filtering by means of concurrent trigger algorithms; (iii) composition of the filteredmore » events into post-trigger files; (iv) persistent data storage. The TriDAS implementation is reported together with a review of dedicated on-line monitoring tools.« less

Database and interactive monitoring system for the photonics and electronics of RPC Muon Trigger in CMS experiment

NASA Astrophysics Data System (ADS)

Wiacek, Daniel; Kudla, Ignacy M.; Pozniak, Krzysztof T.; Bunkowski, Karol

2005-02-01

The main task of the RPC (Resistive Plate Chamber) Muon Trigger monitoring system design for the CMS (Compact Muon Solenoid) experiment (at LHC in CERN Geneva) is the visualization of data that includes the structure of electronic trigger system (e.g. geometry and imagery), the way of its processes and to generate automatically files with VHDL source code used for programming of the FPGA matrix. In the near future, the system will enable the analysis of condition, operation and efficiency of individual Muon Trigger elements, registration of information about some Muon Trigger devices and present previously obtained results in interactive presentation layer. A broad variety of different database and programming concepts for design of Muon Trigger monitoring system was presented in this article. The structure and architecture of the system and its principle of operation were described. One of ideas for building this system is use object-oriented programming and design techniques to describe real electronics systems through abstract object models stored in database and implement these models in Java language.

Spacewire on Earth orbiting scatterometers

NASA Technical Reports Server (NTRS)

Bachmann, Alex; Lang, Minh; Lux, James; Steffke, Richard

2002-01-01

The need for a high speed, reliable and easy to implement communication link has led to the development of a space flight oriented version of IEEE 1355 called SpaceWire. SpaceWire is based on high-speed (200 Mbps) serial point-to-point links using Low Voltage Differential Signaling (LVDS). SpaceWIre has provisions for routing messages between a large network of processors, using wormhole routing for low overhead and latency. {additionally, there are available space qualified hybrids, which provide the Link layer to the user's bus}. A test bed of multiple digital signal processor breadboards, demonstrating the ability to meet signal processing requirements for an orbiting scatterometer has been implemented using three Astrium MCM-DSPs, each breadboard consists of a Multi Chip Module (MCM) that combines a space qualified Digital Signal Processor and peripherals, including IEEE-1355 links. With the addition of appropriate physical layer interfaces and software on the DSP, the SpaceWire link is used to communicate between processors on the test bed, e.g. sending timing references, commands, status, and science data among the processors. Results are presented on development issues surrounding the use of SpaceWire in this environment, from physical layer implementation (cables, connectors, LVDS drivers) to diagnostic tools, driver firmware, and development methodology. The tools, methods, and hardware, software challenges and preliminary performance are investigated and discussed.

Earthquakes drive large-scale submarine canyon development and sediment supply to deep-ocean basins.

PubMed

Mountjoy, Joshu J; Howarth, Jamie D; Orpin, Alan R; Barnes, Philip M; Bowden, David A; Rowden, Ashley A; Schimel, Alexandre C G; Holden, Caroline; Horgan, Huw J; Nodder, Scott D; Patton, Jason R; Lamarche, Geoffroy; Gerstenberger, Matthew; Micallef, Aaron; Pallentin, Arne; Kane, Tim

2018-03-01

Although the global flux of sediment and carbon from land to the coastal ocean is well known, the volume of material that reaches the deep ocean-the ultimate sink-and the mechanisms by which it is transferred are poorly documented. Using a globally unique data set of repeat seafloor measurements and samples, we show that the moment magnitude ( M w ) 7.8 November 2016 Kaikōura earthquake (New Zealand) triggered widespread landslides in a submarine canyon, causing a powerful "canyon flushing" event and turbidity current that traveled >680 km along one of the world's longest deep-sea channels. These observations provide the first quantification of seafloor landscape change and large-scale sediment transport associated with an earthquake-triggered full canyon flushing event. The calculated interevent time of ~140 years indicates a canyon incision rate of 40 mm year -1 , substantially higher than that of most terrestrial rivers, while synchronously transferring large volumes of sediment [850 metric megatons (Mt)] and organic carbon (7 Mt) to the deep ocean. These observations demonstrate that earthquake-triggered canyon flushing is a primary driver of submarine canyon development and material transfer from active continental margins to the deep ocean.

Earthquakes drive large-scale submarine canyon development and sediment supply to deep-ocean basins

PubMed Central

Mountjoy, Joshu J.; Howarth, Jamie D.; Orpin, Alan R.; Barnes, Philip M.; Bowden, David A.; Rowden, Ashley A.; Schimel, Alexandre C. G.; Holden, Caroline; Horgan, Huw J.; Nodder, Scott D.; Patton, Jason R.; Lamarche, Geoffroy; Gerstenberger, Matthew; Micallef, Aaron; Pallentin, Arne; Kane, Tim

2018-01-01

Although the global flux of sediment and carbon from land to the coastal ocean is well known, the volume of material that reaches the deep ocean—the ultimate sink—and the mechanisms by which it is transferred are poorly documented. Using a globally unique data set of repeat seafloor measurements and samples, we show that the moment magnitude (Mw) 7.8 November 2016 Kaikōura earthquake (New Zealand) triggered widespread landslides in a submarine canyon, causing a powerful “canyon flushing” event and turbidity current that traveled >680 km along one of the world’s longest deep-sea channels. These observations provide the first quantification of seafloor landscape change and large-scale sediment transport associated with an earthquake-triggered full canyon flushing event. The calculated interevent time of ~140 years indicates a canyon incision rate of 40 mm year−1, substantially higher than that of most terrestrial rivers, while synchronously transferring large volumes of sediment [850 metric megatons (Mt)] and organic carbon (7 Mt) to the deep ocean. These observations demonstrate that earthquake-triggered canyon flushing is a primary driver of submarine canyon development and material transfer from active continental margins to the deep ocean. PMID:29546245

Alternative sensor system and MLP neural network for vehicle pedal activity estimation.

PubMed

Wefky, Ahmed M; Espinosa, Felipe; Jiménez, José A; Santiso, Enrique; Rodríguez, José M; Fernández, Alfredo J

2010-01-01

It is accepted that the activity of the vehicle pedals (i.e., throttle, brake, clutch) reflects the driver's behavior, which is at least partially related to the fuel consumption and vehicle pollutant emissions. This paper presents a solution to estimate the driver activity regardless of the type, model, and year of fabrication of the vehicle. The solution is based on an alternative sensor system (regime engine, vehicle speed, frontal inclination and linear acceleration) that reflects the activity of the pedals in an indirect way, to estimate that activity by means of a multilayer perceptron neural network with a single hidden layer.

Helicobacter pylori infection

MedlinePlus

H pylori infection ... H pylori bacteria are most likely passed directly from person to person. This tends to happen during ... bacteria may trigger ulcers in the following way: H pylori enters the mucus layer of the stomach ...

On the Nonlinear Dynamics of a Tunable Shock Micro-switch

NASA Astrophysics Data System (ADS)

Azizi, Saber; Javaheri, Hamid; Ghanati, Parisa

2016-12-01

A tunable shock micro-switch based on piezoelectric excitation is proposed in this study. This model includes a clamped-clamped micro-beam sandwiched with two piezoelectric layers throughout the entire length. Actuation of the piezoelectric layers via a DC voltage leads to an initial axial force in the micro-beam and directly affects on its overall bending stiffness; accordingly enables two-side tuning of both the trigger time and threshold shock. The governing motion equation, in the presence of an electrostatic actuation and a shock wave, is derived using Hamilton's principle. We employ the finite element method based on the Galerkin technique to obtain the temporal and phase responses subjected to three different shock waves including half sine, triangular and rectangular forms. Subsequently, we investigate the effect of the piezoelectric excitations on the threshold shock amplitude and trigger time.

23 CFR Appendix A to Part 1313 - Tamper Resistant Driver's License

Code of Federal Regulations, 2010 CFR

2010-04-01

...) Block graphics. (15) Security fonts and graphics with known hidden flaws. (16) Card stock, layer with colors. (17) Micro-graphics. (18) Retroflective security logos. (19) Machine readable technologies such... permit that has one or more of the following security features: (1) Ghost image. (2) Ghost graphic. (3...

Construction and Design of a full size sTGC prototype for the ATLAS New Small Wheel upgrade

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

For the forthcoming Phase-I upgrade to the LHC (2018/19), the first station of the ATLAS muon end-cap system, Small Wheel, will need to be replaced. The New Small Wheel (NSW) will have to operate in a high background radiation region while reconstructing muon tracks with high precision as well as furnishing information for the Level-1 trigger. In particular, the precision reconstruction of tracks requires a spatial resolution of about 100 μm, and the Level-1 trigger track segments have to be reconstructed with an angular resolution of approximately 1 mrad. The NSW will have two chamber technologies, one primarily devoted tomore » the Level-1 trigger function the small-strip Thin Gap Chambers (sTGC) and one dedicated to precision tracking, Micromegas detectors, (MM). The single sTGC planes of a quadruplet consists of an anode layer of 50 μm gold plated tungsten wire sandwiched between two resistive cathode layers. Behind one of the resistive cathode layers, a PCB with precise machined strips (thus the name sTGC's) spaced every 3.2 mm allows to achieve the position resolution that ranges from 70 to 150 μm, depending on the incident particle angle. Behind the second cathode, a PCB that contains an arrangement of pads, allows for a fast coincidence between successive sTGC layers to tag the passage of a track and reads only the corresponding strips for triggering. To be able to profit from the high accuracy of each of the sTGC planes for trigger purposes, their relative geometrical position between planes has to be controlled to within a precision of about 40 μm in their parallelism, as well (due to the various incident angles), to within a precision of 80 μm in the relative distance between the planes to achieve the overall angular resolution of 1 mrad. The needed accuracy in the position and parallelism of the strips is achieved by machining brass inserts together when machining the strip patterns into the cathode boards in a single step. The inserts can then be used as external references on a granite table. Precision methods are used to maintain high accuracy when combining four single detector gaps first into two doublets and then into a quadruplet. We will present results on the ongoing construction of full size (∼1 x 1 m) sTGC quadruplet prototypes before full construction starts in 2015. (authors)« less

The need for drugged driving per se laws: a commentary.

PubMed

DuPont, Robert L; Voas, Robert B; Walsh, J Michael; Shea, Corinne; Talpins, Stephen K; Neil, Mark M

2012-01-01

Triggered by the new federal commitment announced by the Office of National Drug Control Policy (ONCDP) to encourage states to enact drugged driving per se laws, this article reviews the reasons to establish such laws and the issues that may arise when trying to enforce them. A review of the state of drunk driving per se laws and their implications for drugged driving is presented, with a review of impaired driving enforcement procedures and drug testing technology. Currently, enforcement of drugged driving laws is an adjunct to the enforcement of laws regarding alcohol impairment. Drivers are apprehended when showing signs of alcohol intoxication and only in the relatively few cases where the blood alcohol concentration of the arrested driver does not account for the observed behavior is the possibility of drug impairment pursued. In most states, the term impaired driving covers both alcohol and drug impairment; thus, driver conviction records may not distinguish between the two different sources of impairment. As a result, enforcement statistics do not reflect the prevalence of drugged driving. Based on the analysis presented, this article recommends a number of steps that can be taken to evaluate current drugged driving enforcement procedures and to move toward the enactment of drug per se laws.

Global fire at the Cretaceous-Tertiary boundary

NASA Technical Reports Server (NTRS)

Wolbach, Wendy S.; Gilmour, Iain; Anders, Edward; Orth, Charles J.; Brooks, Robert R.

1988-01-01

Cretaceous-Tertiary boundary clays rich in iridium from five sites in Europe and New Zealand were investigated. The clays are found to be 100-10,000-fold-enriched in elemental carbon (mainly soot), which is isotopically uniform and apparently comes from a single global fire. The soot layer coincides with the iridium layer, suggesting that the fire was triggered by meteorite impact and began before the ejecta had settled.

Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance

PubMed Central

Fazakerley, Daniel J; Chaudhuri, Rima; Yang, Pengyi; Maghzal, Ghassan J; Thomas, Kristen C; Krycer, James R; Humphrey, Sean J; Parker, Benjamin L; Fisher-Wellman, Kelsey H; Meoli, Christopher C; Hoffman, Nolan J; Diskin, Ciana; Burchfield, James G; Cowley, Mark J; Kaplan, Warren; Modrusan, Zora; Kolumam, Ganesh; Yang, Jean YH; Chen, Daniel L; Samocha-Bonet, Dorit; Greenfield, Jerry R; Hoehn, Kyle L

2018-01-01

Insulin resistance in muscle, adipocytes and liver is a gateway to a number of metabolic diseases. Here, we show a selective deficiency in mitochondrial coenzyme Q (CoQ) in insulin-resistant adipose and muscle tissue. This defect was observed in a range of in vitro insulin resistance models and adipose tissue from insulin-resistant humans and was concomitant with lower expression of mevalonate/CoQ biosynthesis pathway proteins in most models. Pharmacologic or genetic manipulations that decreased mitochondrial CoQ triggered mitochondrial oxidants and insulin resistance while CoQ supplementation in either insulin-resistant cell models or mice restored normal insulin sensitivity. Specifically, lowering of mitochondrial CoQ caused insulin resistance in adipocytes as a result of increased superoxide/hydrogen peroxide production via complex II. These data suggest that mitochondrial CoQ is a proximal driver of mitochondrial oxidants and insulin resistance, and that mechanisms that restore mitochondrial CoQ may be effective therapeutic targets for treating insulin resistance. PMID:29402381

Flood, Seismic or Volcanic Deposits? New Insights from X-Ray Computed Tomography

NASA Astrophysics Data System (ADS)

Van Daele, M. E.; Moernaut, J.; Vermassen, F.; Llurba, M.; Praet, N.; Strupler, M. M.; Anselmetti, F.; Cnudde, V.; Haeussler, P. J.; Pino, M.; Urrutia, R.; De Batist, M. A. O.

2014-12-01

Event deposits, such as e.g. turbidites incorporated in marine or lacustrine sediment sequences, may be caused by a wide range of possible triggering processes: failure of underwater slopes - either spontaneous or in response to earthquake shaking, hyperpycnal flows and floods, volcanic processes, etc. Determining the exact triggering process remains, however, a major challenge. Especially when studying the event deposits on sediment cores, which typically have diameters of only a few cm, only a small spatial window is available to analyze diagnostic textural and facies characteristics. We have performed X-ray CT scans on sediment cores from Chilean, Alaskan and Swiss lakes. Even when using relatively low-resolution CT scans (0.6 mm voxel size), many sedimentary structures and fabrics that are not visible by eye, are revealed. For example, the CT scans allow to distinguish tephra layers that are deposited by fall-out, from those that reached the basin by river transport or mud flows and from tephra layers that have been reworked and re-deposited by turbidity currents. The 3D data generated by the CT scans also allow to examine relative orientations of sedimentary structures (e.g. convolute lamination) and fabrics (e.g. imbricated mud clasts), which can be used to reconstruct flow directions. Such relative flow directions allow to determine whether a deposit (e.g. a turbidite) had one or several source areas, the latter being typical for seismically triggered turbidites. When the sediment core can be oriented (e.g. using geomagnetic properties), absolute flow directions can be reconstructed. X-ray CT scanning, at different resolution, is thus becoming an increasingly important tool for discriminating the exact origin of EDs, as it can help determining whether e.g. an ash layer was deposited as fall out from an ash cloud or fluvially washed into the lake, or whether a turbidite was triggered by an earthquake or a flood.

Event Recognition Based on Deep Learning in Chinese Texts

PubMed Central

Zhang, Yajun; Liu, Zongtian; Zhou, Wen

2016-01-01

Event recognition is the most fundamental and critical task in event-based natural language processing systems. Existing event recognition methods based on rules and shallow neural networks have certain limitations. For example, extracting features using methods based on rules is difficult; methods based on shallow neural networks converge too quickly to a local minimum, resulting in low recognition precision. To address these problems, we propose the Chinese emergency event recognition model based on deep learning (CEERM). Firstly, we use a word segmentation system to segment sentences. According to event elements labeled in the CEC 2.0 corpus, we classify words into five categories: trigger words, participants, objects, time and location. Each word is vectorized according to the following six feature layers: part of speech, dependency grammar, length, location, distance between trigger word and core word and trigger word frequency. We obtain deep semantic features of words by training a feature vector set using a deep belief network (DBN), then analyze those features in order to identify trigger words by means of a back propagation neural network. Extensive testing shows that the CEERM achieves excellent recognition performance, with a maximum F-measure value of 85.17%. Moreover, we propose the dynamic-supervised DBN, which adds supervised fine-tuning to a restricted Boltzmann machine layer by monitoring its training performance. Test analysis reveals that the new DBN improves recognition performance and effectively controls the training time. Although the F-measure increases to 88.11%, the training time increases by only 25.35%. PMID:27501231

Event Recognition Based on Deep Learning in Chinese Texts.

PubMed

Zhang, Yajun; Liu, Zongtian; Zhou, Wen

2016-01-01

Event recognition is the most fundamental and critical task in event-based natural language processing systems. Existing event recognition methods based on rules and shallow neural networks have certain limitations. For example, extracting features using methods based on rules is difficult; methods based on shallow neural networks converge too quickly to a local minimum, resulting in low recognition precision. To address these problems, we propose the Chinese emergency event recognition model based on deep learning (CEERM). Firstly, we use a word segmentation system to segment sentences. According to event elements labeled in the CEC 2.0 corpus, we classify words into five categories: trigger words, participants, objects, time and location. Each word is vectorized according to the following six feature layers: part of speech, dependency grammar, length, location, distance between trigger word and core word and trigger word frequency. We obtain deep semantic features of words by training a feature vector set using a deep belief network (DBN), then analyze those features in order to identify trigger words by means of a back propagation neural network. Extensive testing shows that the CEERM achieves excellent recognition performance, with a maximum F-measure value of 85.17%. Moreover, we propose the dynamic-supervised DBN, which adds supervised fine-tuning to a restricted Boltzmann machine layer by monitoring its training performance. Test analysis reveals that the new DBN improves recognition performance and effectively controls the training time. Although the F-measure increases to 88.11%, the training time increases by only 25.35%.

Soil respiration across a permafrost transition zone: spatial structure and environmental correlates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stegen, James C.; Anderson, Carolyn G.; Bond-Lamberty, Ben

Soil respiration is a key ecosystem function whereby shifts in respiration rates can shift systems from carbon sinks to sources. Soil respiration in permafrost-associated systems is particularly important given climate change driven permafrost thaw that leads to significant uncertainty in resulting ecosystem carbon dynamics. Here we characterize the spatial structure and environmental drivers of soil respiration across a permafrost transition zone. We find that soil respiration is characterized by a non-linear threshold that occurs at active-layer depths greater than 140 cm. We also find that within each season, tree basal area is a dominant driver of soil respiration regardless of spatial scale, but onlymore » in spatial domains with significant spatial variability in basal area. Our analyses further show that spatial variation (the coefficient of variation) and mean-variance power-law scaling of soil respiration in our boreal system are consistent with previous work in other ecosystems (e.g., tropical forests) and in population ecology, respectively. Comparing our results to those in other ecosystems suggests that temporally stable features such as tree-stand structure are often primary drivers of spatial variation in soil respiration. If so, this provides an opportunity to better estimate the magnitude and spatial variation in soil respiration through remote sensing. Finally, combining such an approach with broader knowledge of thresholding behavior – here related to active layer depth – would provide empirical constraints on models aimed at predicting ecosystem responses to ongoing permafrost thaw.« less

Soil respiration across a permafrost transition zone: spatial structure and environmental correlates

DOE PAGES

Stegen, James C.; Anderson, Carolyn G.; Bond-Lamberty, Ben; ...

2017-09-28

Soil respiration is a key ecosystem function whereby shifts in respiration rates can shift systems from carbon sinks to sources. Soil respiration in permafrost-associated systems is particularly important given climate change driven permafrost thaw that leads to significant uncertainty in resulting ecosystem carbon dynamics. Here we characterize the spatial structure and environmental drivers of soil respiration across a permafrost transition zone. We find that soil respiration is characterized by a non-linear threshold that occurs at active-layer depths greater than 140 cm. We also find that within each season, tree basal area is a dominant driver of soil respiration regardless of spatial scale, but onlymore » in spatial domains with significant spatial variability in basal area. Our analyses further show that spatial variation (the coefficient of variation) and mean-variance power-law scaling of soil respiration in our boreal system are consistent with previous work in other ecosystems (e.g., tropical forests) and in population ecology, respectively. Comparing our results to those in other ecosystems suggests that temporally stable features such as tree-stand structure are often primary drivers of spatial variation in soil respiration. If so, this provides an opportunity to better estimate the magnitude and spatial variation in soil respiration through remote sensing. Finally, combining such an approach with broader knowledge of thresholding behavior – here related to active layer depth – would provide empirical constraints on models aimed at predicting ecosystem responses to ongoing permafrost thaw.« less

Soil respiration across a permafrost transition zone: spatial structure and environmental correlates

NASA Astrophysics Data System (ADS)

Stegen, James C.; Anderson, Carolyn G.; Bond-Lamberty, Ben; Crump, Alex R.; Chen, Xingyuan; Hess, Nancy

2017-09-01

Soil respiration is a key ecosystem function whereby shifts in respiration rates can shift systems from carbon sinks to sources. Soil respiration in permafrost-associated systems is particularly important given climate change driven permafrost thaw that leads to significant uncertainty in resulting ecosystem carbon dynamics. Here we characterize the spatial structure and environmental drivers of soil respiration across a permafrost transition zone. We find that soil respiration is characterized by a non-linear threshold that occurs at active-layer depths greater than 140 cm. We also find that within each season, tree basal area is a dominant driver of soil respiration regardless of spatial scale, but only in spatial domains with significant spatial variability in basal area. Our analyses further show that spatial variation (the coefficient of variation) and mean-variance power-law scaling of soil respiration in our boreal system are consistent with previous work in other ecosystems (e.g., tropical forests) and in population ecology, respectively. Comparing our results to those in other ecosystems suggests that temporally stable features such as tree-stand structure are often primary drivers of spatial variation in soil respiration. If so, this provides an opportunity to better estimate the magnitude and spatial variation in soil respiration through remote sensing. Combining such an approach with broader knowledge of thresholding behavior - here related to active layer depth - would provide empirical constraints on models aimed at predicting ecosystem responses to ongoing permafrost thaw.

Analytical model of tilted driver–pickup coils for eddy current nondestructive evaluation

NASA Astrophysics Data System (ADS)

Cao, Bing-Hua; Li, Chao; Fan, Meng-Bao; Ye, Bo; Tian, Gui-Yun

2018-03-01

A driver-pickup probe possesses better sensitivity and flexibility due to individual optimization of a coil. It is frequently observed in an eddy current (EC) array probe. In this work, a tilted non-coaxial driver-pickup probe above a multilayered conducting plate is analytically modeled with spatial transformation for eddy current nondestructive evaluation. Basically, the core of the formulation is to obtain the projection of magnetic vector potential (MVP) from the driver coil onto the vector along the tilted pickup coil, which is divided into two key steps. The first step is to make a projection of MVP along the pickup coil onto a horizontal plane, and the second one is to build the relationship between the projected MVP and the MVP along the driver coil. Afterwards, an analytical model for the case of a layered plate is established with the reflection and transmission theory of electromagnetic fields. The calculated values from the resulting model indicate good agreement with those from the finite element model (FEM) and experiments, which validates the developed analytical model. Project supported by the National Natural Science Foundation of China (Grant Nos. 61701500, 51677187, and 51465024).

NIR‐Triggered Crystal Phase Transformation of NiTi‐Layered Double Hydroxides Films for Localized Chemothermal Tumor Therapy

PubMed Central

Wang, Donghui; Ge, Naijian; Yang, Tingting; Peng, Feng; Qiao, Yuqin; Li, Qianwen

2018-01-01

Abstract Construction of localized drug‐eluting systems with synergistic chemothermal tumor‐killing abilities is promising for biomedical implants directly contacting with tumor tissues. In this study, an intelligent and biocompatible drug‐loading platform, based on a gold nanorods‐modified butyrate‐inserted NiTi‐layered double hydroxides film (Au@LDH/B), is prepared on the surface of nitinol alloy. The prepared films function as drug‐loading “sponges,” which pump butyrate out under near‐infrared (NIR) irradiation and resorb drugs in water when the NIR laser is shut off. The stimuli‐responsive release of butyrate is verified to be related with the NIR‐triggered crystal phase transformation of Au@LDH/B. In vitro and in vivo studies reveal that the prepared films possess excellent biosafety and high efficiency in synergistic thermochemo tumor therapy, showing a promising application in the construction of localized stimuli‐responsive drug‐delivery systems. PMID:29721424

p-wave triggered superconductivity in single-layer graphene on an electron-doped oxide superconductor.

PubMed

Di Bernardo, A; Millo, O; Barbone, M; Alpern, H; Kalcheim, Y; Sassi, U; Ott, A K; De Fazio, D; Yoon, D; Amado, M; Ferrari, A C; Linder, J; Robinson, J W A

2017-01-19

Electron pairing in the vast majority of superconductors follows the Bardeen-Cooper-Schrieffer theory of superconductivity, which describes the condensation of electrons into pairs with antiparallel spins in a singlet state with an s-wave symmetry. Unconventional superconductivity was predicted in single-layer graphene (SLG), with the electrons pairing with a p-wave or chiral d-wave symmetry, depending on the position of the Fermi energy with respect to the Dirac point. By placing SLG on an electron-doped (non-chiral) d-wave superconductor and performing local scanning tunnelling microscopy and spectroscopy, here we show evidence for a p-wave triggered superconducting density of states in SLG. The realization of unconventional superconductivity in SLG offers an exciting new route for the development of p-wave superconductivity using two-dimensional materials with transition temperatures above 4.2 K.

p-wave triggered superconductivity in single-layer graphene on an electron-doped oxide superconductor

PubMed Central

Di Bernardo, A.; Millo, O.; Barbone, M.; Alpern, H.; Kalcheim, Y.; Sassi, U.; Ott, A. K.; De Fazio, D.; Yoon, D.; Amado, M.; Ferrari, A. C.; Linder, J.; Robinson, J. W. A.

2017-01-01

Electron pairing in the vast majority of superconductors follows the Bardeen–Cooper–Schrieffer theory of superconductivity, which describes the condensation of electrons into pairs with antiparallel spins in a singlet state with an s-wave symmetry. Unconventional superconductivity was predicted in single-layer graphene (SLG), with the electrons pairing with a p-wave or chiral d-wave symmetry, depending on the position of the Fermi energy with respect to the Dirac point. By placing SLG on an electron-doped (non-chiral) d-wave superconductor and performing local scanning tunnelling microscopy and spectroscopy, here we show evidence for a p-wave triggered superconducting density of states in SLG. The realization of unconventional superconductivity in SLG offers an exciting new route for the development of p-wave superconductivity using two-dimensional materials with transition temperatures above 4.2 K. PMID:28102222

The phase 1 upgrade of the CMS Pixel Front-End Driver

NASA Astrophysics Data System (ADS)

Friedl, M.; Pernicka, M.; Steininger, H.

2010-12-01

The pixel detector of the CMS experiment at the LHC is read out by analog optical links, sending the data to 9U VME Front-End Driver (FED) boards located in the electronics cavern. There are plans for the phase 1 upgrade of the pixel detector (2016) to add one more layer, while significantly cutting down the overall material budget. At the same time, the optical data transmission will be replaced by a serialized digital scheme. A plug-in board solution with a high-speed digital optical receiver has been developed for the Pixel-FED readout boards and will be presented along with first tests of the future optical link.

The effects of fire on the thermal stability of permafrost in lowland and upland black spruce forests of interior Alaska in a changing climate

Treesearch

E.E. Jafarov; V.E. Romanovsky; H. Genet; A.D. McGuire; S.S. Marchenko

2013-01-01

Fire is an important factor controlling the composition and thickness of the organic layer in the black spruce forest ecosystems of interior Alaska. Fire that burns the organic layer can trigger dramatic changes in the underlying permafrost, leading to accelerated ground thawing within a relatively short time. In this study, we addressed the following questions. (1)...

Energetic composites

DOEpatents

Danen, Wayne C.; Martin, Joe A.

1993-01-01

A method for providing chemical energy and energetic compositions of matter consisting of thin layers of substances which will exothermically react with one another. The layers of reactive substances are separated by thin layers of a buffer material which prevents the reactions from taking place until the desired time. The reactions are triggered by an external agent, such as mechanical stress or an electric spark. The compositions are known as metastable interstitial composites (MICs). This class of compositions includes materials which have not previously been capable of use as energetic materials. The speed and products of the reactions can be varied to suit the application.

Energetic composites

DOEpatents

Danen, W.C.; Martin, J.A.

1993-11-30

A method for providing chemical energy and energetic compositions of matter consisting of thin layers of substances which will exothermically react with one another. The layers of reactive substances are separated by thin layers of a buffer material which prevents the reactions from taking place until the desired time. The reactions are triggered by an external agent, such as mechanical stress or an electric spark. The compositions are known as metastable interstitial composites (MICs). This class of compositions includes materials which have not previously been capable of use as energetic materials. The speed and products of the reactions can be varied to suit the application. 3 figures.

Versatile digital micromirror device-based method for the recording of multilevel optical diffractive elements in photosensitive chalcogenide layers (AMTIR-1).

PubMed

Joerg, Alexandre; Vignaux, Mael; Lumeau, Julien

2016-08-01

A new alternative and versatile method for the production of diffractive optical elements (DOEs) with up to four phase levels in AMTIR-1 (Ge₃₃As₁₂Se₅₅) layers is demonstrated. The developed method proposes the use of the photosensitive properties of the layers and a specific in situ optical monitoring coupled with a reverse engineering algorithm to control the trigger points of the writing of the different diffractive patterns. Examples of various volume DOEs are presented.

Climate drivers of the Amazon forest greening.

PubMed

Wagner, Fabien Hubert; Hérault, Bruno; Rossi, Vivien; Hilker, Thomas; Maeda, Eduardo Eiji; Sanchez, Alber; Lyapustin, Alexei I; Galvão, Lênio Soares; Wang, Yujie; Aragão, Luiz E O C

2017-01-01

Our limited understanding of the climate controls on tropical forest seasonality is one of the biggest sources of uncertainty in modeling climate change impacts on terrestrial ecosystems. Combining leaf production, litterfall and climate observations from satellite and ground data in the Amazon forest, we show that seasonal variation in leaf production is largely triggered by climate signals, specifically, insolation increase (70.4% of the total area) and precipitation increase (29.6%). Increase of insolation drives leaf growth in the absence of water limitation. For these non-water-limited forests, the simultaneous leaf flush occurs in a sufficient proportion of the trees to be observed from space. While tropical cycles are generally defined in terms of dry or wet season, we show that for a large part of Amazonia the increase in insolation triggers the visible progress of leaf growth, just like during spring in temperate forests. The dependence of leaf growth initiation on climate seasonality may result in a higher sensitivity of these ecosystems to changes in climate than previously thought.

Ventilation and Heart Rate Monitoring in Drivers using a Contactless Electrical Bioimpedance System

NASA Astrophysics Data System (ADS)

Macías, R.; García, M. A.; Ramos, J.; Bragós, R.; Fernández, M.

2013-04-01

Nowadays, the road safety is one of the most important priorities in the automotive industry. Many times, this safety is jeopardized because of driving under inappropriate states, e.g. drowsiness, drugs and/or alcohol. Therefore several systems for monitoring the behavior of subjects during driving are researched. In this paper, a device based on a contactless electrical bioimpedance system is shown. Using the four-wire technique, this system is capable of obtaining the heart rate and the ventilation of the driver through multiple textile electrodes. These textile electrodes are placed on the car seat and the steering wheel. Moreover, it is also reported several measurements done in a controlled environment, i.e. a test room where there are no artifacts due to the car vibrations or the road state. In the mentioned measurements, the system response can be observed depending on several parameters such as the placement of the electrodes or the number of clothing layers worn by the driver.

A recellularized human colon model identifies cancer driver genes

PubMed Central

Chen, Huanhuan Joyce; Wei, Zhubo; Sun, Jian; Bhattacharya, Asmita; Savage, David J; Serda, Rita; Mackeyev, Yuri; Curley, Steven A.; Bu, Pengcheng; Wang, Lihua; Chen, Shuibing; Cohen-Gould, Leona; Huang, Emina; Shen, Xiling; Lipkin, Steven M.; Copeland, Neal G.; Jenkins, Nancy A.; Shuler, Michael L.

2016-01-01

Refined cancer models are needed to bridge the gap between cell-line, animal and clinical research. Here we describe the engineering of an organotypic colon cancer model by recellularization of a native human matrix that contains cell-populated mucosa and an intact muscularis mucosa layer. This ex vivo system recapitulates the pathophysiological progression from APC-mutant neoplasia to submucosal invasive tumor. We used it to perform a Sleeping Beauty transposon mutagenesis screen to identify genes that cooperate with mutant APC in driving invasive neoplasia. 38 candidate invasion driver genes were identified, 17 of which have been previously implicated in colorectal cancer progression, including TCF7L2, TWIST2, MSH2, DCC and EPHB1/2. Six invasion driver genes that to our knowledge have not been previously described were validated in vitro using cell proliferation, migration and invasion assays, and ex vivo using recellularized human colon. These results demonstrate the utility of our organoid model for studying cancer biology. PMID:27398792

Liquefaction features interpreted as seismites in the Pleistocene fluvio-lacustrine deposits of the Neuquén Basin (Northern Patagonia)

NASA Astrophysics Data System (ADS)

Moretti, M.; Ronchi, A.

2011-04-01

Superbly exposed soft-sediment deformation structures in Pleistocene fluvio-lacustrine deposits along the southern border of the depression area called Bajo de Añelo (Departamento de Añelo, Neuquén Basin) have been analysed. In the study area, five stratigraphic sections were measured in detail: facies distributions and stacking patterns show that these sediments result from the interaction between fluvial and lacustrine systems, represented by cross-bedded and rippled strata, and varved deposits. The lateral extent of the deformation is some hundred metres and the deformed bed involves the lower-mid part of the 30-metre-thick succession. Deformation affects about 1.5 m of coarse-grained sand, fine-grained sand and rare gravel alternations. The base and top of the deformed layer are defined by planar surfaces: undeformed beds of similar thickness, lithology and facies to the deformed layer occur above and below. Deformation is represented by a complex vertical succession of disturbed layers: each layer shows a general load-structure morphology. It can be described as a multilayered unstable density gradient system: in each bed a partial gravitational re-adjustment occurred after liquefaction. Unequal loading related to lateral variation of both bed thickness and grain packing and porosity is a probable additional driving force that can be described in the undeformed beds. Trigger mechanism recognition for the observed liquefaction features can be based on the study of the geometry of deformed beds and on facies analysis results. Two key factors drive our interpretation: (1) the occurrence of undeformed beds below and above the deformed bed; (2) deformed and undeformed beds showing the same sedimentological features. These field data allow us to exclude the action of internal erosive and/or sedimentary processes (such as overloading, wave action, etc.) as possible trigger agents for liquefaction since deformation is totally absent in beds with similar sedimentary features. Furthermore, each internal erosive and/or sedimentary process can be discussed and easily excluded by analysing its specific signature in the geological record. Having excluded every possible internal trigger (autokinetic processes), the observed liquefaction effects can reasonably be interpreted as seismically induced (allokinetic trigger). From this point of view, this deformed bed is an important record of seismic activity in this sector of the Neuquén Basin during the Pleistocene.

Bivalve aquaculture-environment interactions in the context of climate change.

PubMed

Filgueira, Ramón; Guyondet, Thomas; Comeau, Luc A; Tremblay, Réjean

2016-12-01

Coastal embayments are at risk of impacts by climate change drivers such as ocean warming, sea level rise and alteration in precipitation regimes. The response of the ecosystem to these drivers is highly dependent on their magnitude of change, but also on physical characteristics such as bay morphology and river discharge, which play key roles in water residence time and hence estuarine functioning. These considerations are especially relevant for bivalve aquaculture sites, where the cultured biomass can alter ecosystem dynamics. The combination of climate change, physical and aquaculture drivers can result in synergistic/antagonistic and nonlinear processes. A spatially explicit model was constructed to explore effects of the physical environment (bay geomorphic type, freshwater inputs), climate change drivers (sea level, temperature, precipitation) and aquaculture (bivalve species, stock) on ecosystem functioning. A factorial design led to 336 scenarios (48 hydrodynamic × 7 management). Model outcomes suggest that the physical environment controls estuarine functioning given its influence on primary productivity (bottom-up control dominated by riverine nutrients) and horizontal advection with the open ocean (dominated by bay geomorphic type). The intensity of bivalve aquaculture ultimately determines the bivalve-phytoplankton trophic interaction, which can range from a bottom-up control triggered by ammonia excretion to a top-down control via feeding. Results also suggest that temperature is the strongest climate change driver due to its influence on the metabolism of poikilothermic organisms (e.g. zooplankton and bivalves), which ultimately causes a concomitant increase of top-down pressure on phytoplankton. Given the different thermal tolerance of cultured species, temperature is also critical to sort winners from losers, benefiting Crassostrea virginica over Mytilus edulis under the specific conditions tested in this numerical exercise. In general, it is predicted that bays with large rivers and high exchange with the open ocean will be more resilient under climate change when bivalve aquaculture is present. © 2016 John Wiley & Sons Ltd.

Medical review licensing outcomes in drivers with visual field loss in Victoria, Australia

PubMed Central

Muir, Carlyn; Charlton, Judith L; Odell, Morris; Keeffe, Jill; Wood, Joanne; Bohensky, Megan; Fildes, Brian; Oxley, Jennifer; Bentley, Sharon; Rizzo, Matthew

2017-01-01

Background Good vision is essential for safe driving and studies have associated visual impairment with an increased crash risk. Currently, there is little information about the medical review of drivers with visual field loss. This study examines the prevalence of visual field loss among drivers referred for medical review in one Australian jurisdiction and investigates factors associated with licence outcome in this group. Methods A random sample of 10,000 (31.25 per cent) medical review cases was extracted for analysis from the Victorian licensing authority. Files were screened for the presence of six visual field-related medical conditions. Data were captured on a range of variables, including referral source, age, gender, health status, crash history and licence outcome. Prevalence analyses were univariate and descriptive. Logistic regression was used to assess factors associated with licence outcomes in the visual field loss group. Results Approximately 1.9 per cent of the 10,000 medical review cases screened had a visual field loss condition identified (n=194). Among the visual field loss group, 57.2 per cent were permitted to continue driving (conditional/unconditional licence). Primary referral sources were the police, self-referrals and general medical practitioners. Key factors associated with licence test outcomes were visual field condition, age group, crash involvement and referral to the Driver Licensing Authority’s Medical Advisors. Those who were younger had a crash involvement triggering referral and those who were referred to the Medical Advisors were more likely to have a positive licensing outcome. Conclusion The evidence base for making licensing decisions is complicated by the variable causes, patterns, progressions and measuring technologies for visual field loss. This study highlighted that the involvement of an expert medical advisory service in Victoria resulted in an increased likelihood that drivers with visual field loss will be allowed to continue driving. Further research is warranted to explore issues relating to severity of field loss and the capacity for compensation. PMID:27530283

Improving understanding of trigger points and widespread pressure pain sensitivity in tension-type headache patients: clinical implications.

PubMed

Fernández-De-Las-Peñas, César; Arendt-Nielsen, Lars

2017-09-01

The underlying etiology of tension type headache (TTH) is not understood. The current paper highlights the etiologic role of muscle trigger points (TrPs) to the development and maintenance of central sensitization in TTH and its clinical repercussion for proper management of these patients. Areas covered: A literature search on Pub Med for English-language published papers between 1990 and May 2017 to provide the most updated data on the topic was conducted. Current literature suggests that the referred pain elicited by active trigger points (TrPs) contributes to the manifestations of TTH. There is also evidence supporting that TrPs represent a peripheral source of nociception and thereby a driver in the development of central sensitization. In fact, TrPs have been found to be associated with widespread pressure pain sensitivity in TTH. Temporal and spatial summation of TrP nociception suggests that inactivating TrP in the neck, head and shoulder muscles could help these patients; however, current evidence supporting the therapeutic role of TrPs in TTH is conflicting. Expert commentary: Understanding the role of TrPs in TTH in widespread pain sensitization may help to develop better management regimes and possibly prevent TTH from developing into more chronic conditions.

Death from drought in tropical forests is triggered by hydraulics not carbon starvation

NASA Astrophysics Data System (ADS)

Rowland, L.; da Costa, A. C. L.; Galbraith, D. R.; Oliveira, R. S.; Binks, O. J.; Oliveira, A. A. R.; Pullen, A. M.; Doughty, C. E.; Metcalfe, D. B.; Vasconcelos, S. S.; Ferreira, L. V.; Malhi, Y.; Grace, J.; Mencuccini, M.; Meir, P.

2015-12-01

Drought threatens tropical rainforests over seasonal to decadal timescales, but the drivers of tree mortality following drought remain poorly understood. It has been suggested that reduced availability of non-structural carbohydrates (NSC) critically increases mortality risk through insufficient carbon supply to metabolism (‘carbon starvation’). However, little is known about how NSC stores are affected by drought, especially over the long term, and whether they are more important than hydraulic processes in determining drought-induced mortality. Using data from the world’s longest-running experimental drought study in tropical rainforest (in the Brazilian Amazon), we test whether carbon starvation or deterioration of the water-conducting pathways from soil to leaf trigger tree mortality. Biomass loss from mortality in the experimentally droughted forest increased substantially after >10 years of reduced soil moisture availability. The mortality signal was dominated by the death of large trees, which were at a much greater risk of hydraulic deterioration than smaller trees. However, we find no evidence that the droughted trees suffered carbon starvation, as their NSC concentrations were similar to those of non-droughted trees, and growth rates did not decline in either living or dying trees. Our results indicate that hydraulics, rather than carbon starvation, triggers tree death from drought in tropical rainforest.

Death from drought in tropical forests is triggered by hydraulics not carbon starvation.

PubMed

Rowland, L; da Costa, A C L; Galbraith, D R; Oliveira, R S; Binks, O J; Oliveira, A A R; Pullen, A M; Doughty, C E; Metcalfe, D B; Vasconcelos, S S; Ferreira, L V; Malhi, Y; Grace, J; Mencuccini, M; Meir, P

2015-12-03

Drought threatens tropical rainforests over seasonal to decadal timescales, but the drivers of tree mortality following drought remain poorly understood. It has been suggested that reduced availability of non-structural carbohydrates (NSC) critically increases mortality risk through insufficient carbon supply to metabolism ('carbon starvation'). However, little is known about how NSC stores are affected by drought, especially over the long term, and whether they are more important than hydraulic processes in determining drought-induced mortality. Using data from the world's longest-running experimental drought study in tropical rainforest (in the Brazilian Amazon), we test whether carbon starvation or deterioration of the water-conducting pathways from soil to leaf trigger tree mortality. Biomass loss from mortality in the experimentally droughted forest increased substantially after >10 years of reduced soil moisture availability. The mortality signal was dominated by the death of large trees, which were at a much greater risk of hydraulic deterioration than smaller trees. However, we find no evidence that the droughted trees suffered carbon starvation, as their NSC concentrations were similar to those of non-droughted trees, and growth rates did not decline in either living or dying trees. Our results indicate that hydraulics, rather than carbon starvation, triggers tree death from drought in tropical rainforest.

Capacitance of the Double Layer Formed at the Metal/Ionic-Conductor Interface: How Large Can It Be?

NASA Astrophysics Data System (ADS)

Skinner, Brian; Loth, M. S.; Shklovskii, B. I.

2010-03-01

The capacitance of the double layer formed at a metal/ionic-conductor interface can be remarkably large, so that the apparent width of the double layer is as small as 0.3 Å. Mean-field theories fail to explain such large capacitance. We propose an alternate theory of the ionic double layer which allows for the binding of discrete ions to their image charges in the metal. We show that at small voltages the capacitance of the double layer is limited only by the weak dipole-dipole repulsion between bound ions, and is therefore very large. At large voltages the depletion of bound ions from one of the capacitor electrodes triggers a collapse of the capacitance to the mean-field value.

Long-term impacts of boreal wildfire on carbon cycling dynamics in Interior Alaska

NASA Astrophysics Data System (ADS)

Gaglioti, B.; Mann, D. H.; Finney, B.; Pohlman, J.; Jones, B. M.; Arp, C. D.; Wooller, M. J.

2013-12-01

Wildland fire is a major disturbance in the boreal forest, and warming climate will likely increase the frequency and severity of burning. Fires trigger thermokarst, the thawing of permafrost (perennially frozen ground), which can release large amounts of ancient carbon to the atmosphere. But how vulnerable is the organic carbon stored in permafrost in the boreal forest to a changing fire regime? Paleolimnological records can tell us how the landscape actually responded during prehistoric fires and provide a valuable perspective on future events. Here we present a whole-watershed summary of terrestrial and aquatic carbon dynamics during multiple fire and thermokarst disturbances over the last millennia. We use laminated lake sediments laid down in a permanently stratified, thermokarst lake basin in Interior Alaska to decipher the impacts of wildfires on permafrost carbon release from the surrounding watershed. Sediment chronologies based on layer counts, lead and cesium dating, and radiocarbon dating of plant macrofossils, provide a near-annual resolution of environmental changes over the last 1100 years. Charcoal accumulation rates quantified from sediment thin-sections and fire-scarred spruce trees constrain the timing of fires. The variability of permafrost carbon release before and after fires was investigated by analyzing several geochemical indices including radiocarbon dating on the sediment organic matter directly above and below charcoal layers in the sediment stack. The difference between a sediment layers 'true' age of deposition based on layer counts and the apparent radiocarbon age on the same bulk sediment material (radiocarbon age offset) is then used as a proxy for permafrost carbon release. The relative age of permafrost-derived organic carbon entering the lake before and after past fires was determined by radiocarbon age offsets before and after wildfire events. Fires are not the only triggers of permafrost-C release. Thermokarst caused by shoreline erosion triggered by some combination of fires, beaver dams that raise lake levels, and chance events complicate the larger watershed signal of C release.

Remote sensing observations of phytoplankton increases triggered by successive typhoons

NASA Astrophysics Data System (ADS)

Huang, Lei; Zhao, Hui; Pan, Jiayi; Devlin, Adam

2017-12-01

Phytoplankton blooms in the Western North Pacific, triggered by two successive typhoons with different intensities and translation speeds under different pre-existing oceanic conditions, were observed and analyzed using remotely sensed chlorophyll-a (Chl-a), sea surface temperature (SST), and sea surface height anomaly (SSHA) data, as well as typhoon parameters and CTD (conductivity, temperature, and depth) profiles. Typhoon Sinlaku, with relatively weaker intensity and slower translation speed, induced a stronger phytoplankton bloom than Jangmi with stronger intensity and faster translation speed (Chl-a>0.18 mg·m‒3 versus Chl-a<0.15 mg·m‒3) east of Taiwan Island. Translation speed may be one of the important mechanisms that affect phytoplankton blooms in the study area. Pre-existing cyclonic circulations provided a relatively unstable thermodynamic structure for Sinlaku, and therefore cold water with rich nutrients could be brought up easily. The mixed-layer deepening caused by Typhoon Sinlaku, which occurred first, could have triggered an unfavorable condition for the phytoplankton bloom induced by Typhoon Jangmi which followed afterwards. The sea surface temperature cooling by Jangmi was suppressed due to the presence of the thick upper-ocean mixed-layer, which prevented the deeper cold water from being entrained into the upper-ocean mixed layer, leading to a weaker phytoplankton augment. The present study suggests that both wind (including typhoon translation speed and intensity) and pre-existing conditions (e.g., mixed-layer depths, eddies, and nutrients) play important roles in the strong phytoplankton bloom, and are responsible for the stronger phytoplankton bloom after Sinlaku's passage than that after Jangmi's passage. A new typhoon-influencing parameter is introduced that combines the effects of the typhoon forcing (including the typhoon intensity and translation speed) and the oceanic pre-condition. This parameter shows that the forcing effect of Sinlaku was stronger than that of Jangmi.

Vehicle emission implications of drivers' smart advisory system for traffic operations in work zones.

PubMed

Li, Qing; Qiao, Fengxiang; Yu, Lei

2016-05-01

Wireless communication systems have been broadly applied in various complicated traffic operations to improve mobility and safety on roads, which may raise a concern about the implication of the new technology on vehicle emissions. This paper explores how the wireless communication systems improve drivers' driving behaviors and its contributions to the emission reduction, in terms of Operating Mode (OpMode) IDs distribution used in emission estimation. A simulated work zone with completed traffic operation was selected as a test bed. Sixty subjects were recruited for the tests, whose demographic distribution was based on the Census data in Houston, Texas. A scene of a pedestrian's crossing in the work zone was designed for the driving test. Meanwhile, a wireless communication system called Drivers Smart Advisory System (DSAS) was proposed and introduced in the driving simulation, which provided drivers with warning messages in the work zone. Two scenarios were designed for a leading vehicle as well as for a following vehicle driving through the work zone, which included a base test without any wireless communication systems, and a driving test with the trigger of the DSAS. Subjects' driving behaviors in the simulation were recorded to evaluate safety and estimate the vehicle emission using the Environmental Protection Agency (EPA) released emission model MOVES. The correlation between drivers' driving behavior and the distribution of the OpMode ID during each scenario was investigated. Results show that the DSAS was able to induce drivers to accelerate smoothly, keep longer headway distance and stop earlier for a hazardous situation in the work zone, which driving behaviors result in statistically significant reduction in vehicle emissions for almost all studied air pollutants (p-values range from 4.10E-51 to 2.18E-03). The emission reduction was achieved by the switching the distribution of the OpMode IDs from higher emission zones to lower emission zones. Transportation section is a significant source of greenhouse gas emissions. Many studies demonstrate that the wireless communication system dedicated for safety and mobility issues may contribute to the induction in vehicle emissions through changing driving behaviors. An insight into the correlation between the driving behaviors and the distribution of Operating Mode (OpMode) IDs is essential to enhance the emission reduction. The result of this study shows that with a Drivers Smart Advisory System (DSAS) drivers accelerated smoothly and stopped earlier for a hazardous situation, which induce the switch of the OpMode IDs from high emission zones to lower emission zones.

A combined STM and SPA-LEED study of the “explosive” nucleation and collective diffusion in Pb/Si(111)

DOE PAGES

Hattab, H.; Hupalo, M.; Hershberger, M. T.; ...

2015-08-20

A novel type of very fast nucleation was recently found in Pb/Si(111) with 4- to 7-layer high islands becoming crystalline in an “explosive” way, when the Pb deposited amount in the wetting layer is compressed to θ c ~ 1.22 ML, well above the metallic Pb(111) density. This “explosive” nucleation is very different from classical nucleation when island growth is more gradual and islands grow in size by single adatom aggregation [8]. In order to identify the key parameters that control the nucleation we used scanning tunneling microscopy (STM) and spot profile analysis low energy electron diffraction (SPA-LEED). It wasmore » found that the number and duration of steps in iterative deposition used to approach θc and the flux rate have dramatic effects on the crystallization process. Larger depositions over shorter times induce greater spatial coverage fluctuations, so local areas can reach the critical coverage θ c easier. This can trigger the collective motion of the wetting layer from far away to build the Pb islands “explosively”. Here, the SPA-LEED experiments show that even low flux experiments in iterative deposition experiments can trigger transfer of material to the superstable 7-layer islands, as seen from the stronger satellite rings close to the (00) spot.« less

Arc initiation in cathodic arc plasma sources

DOEpatents

Anders, Andre

2002-01-01

A "triggerless" arc initiation method and apparatus is based on simply switching the arc supply voltage to the electrodes (anode and cathode). Neither a mechanical trigger electrode nor a high voltage flashover from a trigger electrode is required. A conducting path between the anode and cathode is provided, which allows a hot spot to form at a location where the path connects to the cathode. While the conductive path is eroded by the cathode spot action, plasma deposition ensures the ongoing repair of the conducting path. Arc initiation is achieved by simply applying the relatively low voltage of the arc power supply, e.g. 500 V-1 kV, with the insulator between the anode and cathode coated with a conducting layer and the current at the layer-cathode interface concentrated at one or a few contact points. The local power density at these contact points is sufficient for plasma production and thus arc initiation. A conductive surface layer, such as graphite or the material being deposited, is formed on the surface of the insulator which separates the cathode from the anode. The mechanism of plasma production (and arc initiation) is based on explosive destruction of the layer-cathode interface caused by joule heating. The current flow between the thin insulator coating and cathode occurs at only a few contact points so the current density is high.

Application of High-Throughput In Vitro Assays for Risk-Based Chemical Safety Decisions of Environmental and Industrial Chemicals (SOT presentation)

EPA Science Inventory

Multiple drivers shape the types of human-health assessments performed on chemicals by U.S. EPA resulting in chemical assessments are “fit-for-purpose” ranging from prioritization for further testing to full risk assessments. Layered on top of the diverse assessment needs are the...

LLE review. Quarterly report, January 1994--March 1994, Volume 58

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simon, A.

1994-07-01

This volume of the LLE Review, covering the period Jan - Mar 1994, contains articles on backlighting diagnostics; the effect of electron collisions on ion-acoustic waves and heat flow; using PIC code simulations for analysis of ultrashort laser pulses interacting with solid targets; creating a new instrument for characterizing thick cryogenic layers; and a description of a large-aperture ring amplifier for laser-fusion drivers. Three of these articles - backlighting diagnostics; characterizing thick cryogenic layers; and large-aperture ring amplifier - are directly related to the OMEGA Upgrade, now under construction. Separate abstracts have been prepared for articles from this report.

VIPRAM_L1CMS: a 2-Tier 3D Architecture for Pattern Recognition for Track Finding

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hoff, J. R.; Joshi, Joshi,S.; Liu, Liu,

In HEP tracking trigger applications, flagging an individual detector hit is not important. Rather, the path of a charged particle through many detector layers is what must be found. Moreover, given the increased luminosity projected for future LHC experiments, this type of track finding will be required within the Level 1 Trigger system. This means that future LHC experiments require not just a chip capable of high-speed track finding but also one with a high-speed readout architecture. VIPRAM_L1CMS is 2-Tier Vertically Integrated chip designed to fulfill these requirements. It is a complete pipelined Pattern Recognition Associative Memory (PRAM) architecture includingmore » pattern recognition, result sparsification, and readout for Level 1 trigger applications in CMS with 15-bit wide detector addresses and eight detector layers included in the track finding. Pattern recognition is based on classic Content Addressable Memories with a Current Race Scheme to reduce timing complexity and a 4-bit Selective Precharge to minimize power consumption. VIPRAM_L1CMS uses a pipelined set of priority-encoded binary readout structures to sparsify and readout active road flags at frequencies of at least 100MHz. VIPRAM_L1CMS is designed to work directly with the Pulsar2b Architecture.« less

Impact of virus strain characteristics on early detection of highly pathogenic avian influenza infection in commercial table-egg layer flocks and implications for outbreak control.

PubMed

Weaver, J Todd; Malladi, Sasidhar; Goldsmith, Timothy J; Hueston, Will; Hennessey, Morgan; Lee, Brendan; Voss, Shauna; Funk, Janel; Der, Christina; Bjork, Kathe E; Clouse, Timothy L; Halvorson, David A

2012-12-01

Early detection of highly pathogenic avian influenza (HPAI) infection in commercial poultry flocks is a critical component of outbreak control. Reducing the time to detect HPAI infection can reduce the risk of disease transmission to other flocks. The timeliness of different types of detection triggers could be dependent on clinical signs that are first observed in a flock, signs that might vary due to HPAI virus strain characteristics. We developed a stochastic disease transmission model to evaluate how transmission characteristics of various HPAI strains might effect the relative importance of increased mortality, drop in egg production, or daily real-time reverse transcriptase (RRT)-PCR testing, toward detecting HPAI infection in a commercial table-egg layer flock. On average, daily RRT-PCR testing resulted in the shortest time to detection (from 3.5 to 6.1 days) depending on the HPAI virus strain and was less variable over a range of transmission parameters compared with other triggers evaluated. Our results indicate that a trigger to detect a drop in egg production would be useful for HPAI virus strains with long infectious periods (6-8 days) and including an egg-drop detection trigger in emergency response plans would lead to earlier and consistent reporting in some cases. We discuss implications for outbreak control and risk of HPAI spread attributed to different HPAI strain characteristics where an increase in mortality or a drop in egg production or both would be among the first clinical signs observed in an infected flock.

Physical and mathematical modeling of transient infiltration through shallow layered pyroclastic deposits

NASA Astrophysics Data System (ADS)

Damiano, Emilia; Greco, Roberto; Guida, Andrea; Olivares, Lucio; Picarelli, Luciano

2017-04-01

Layered pyroclastic deposits covering steep slopes, characteristic of large mountainous areas of Campania (southern Italy), are often affected by shallow landslides triggered by heavy rainfall events. In fact, the equilibrium of such deposits is usually guaranteed by the contribution to soil shear strength offered by soil suction, which decreases during wetting. As the return period of the triggering events has been in many cases not extreme, other factors concur to establish triggering conditions. In this respect, heterogeneities, strongly affecting transient infiltration, may in some cases play a crucial role. In this study, the effect of the presence of soil layers, characterized by markedly different hydraulic properties, on the rainwater infiltration process is investigated. In fact, the pyroclastic covers of Campania, being the result of the deposition of materials originated by several eruptions of the nearby volcanic complexes, usually consist of alternating layers of ashes (silty sands) and pumices (gravel with sand). The presence of coarse-textured pumices between finer ashes strongly affects the infiltration process. In fact, the pumices, which are characterized by saturated hydraulic conductivity larger than ashes, are capable of retaining less water than ashes in unsaturated conditions, so that their unsaturated hydraulic conductivity is usually very small. Hence, depending on the water potential distribution throughout the cover at the onset of rainfall, pumices may act as a barrier to the propagation of the wet front (the so-called capillary barrier effect), or, approaching saturation, let the water pass through them very quickly. Such a complex behavior has been studied by means of a series of infiltration experiments carried out in an instrumented flume in the Geotechnical Laboratory of the University of Campania (http://www.dicdea.unina2.it/it/dipartimento/laboratori/laboratorio-di-geotecnica). Starting from different initial moisture conditions, small scale physical models of layered slopes, with various geometry and inclination, have been subjected to rainfalls of various intensities. During the infiltration processes and the following water redistribution phases, soil moisture and matric potential have been measured at various locations by means of TDR probes and tensiometers, respectively. The interpretation of the experimental results has been aided by a 2D mathematical model based on the integration of Richards' equation with the finite differences method. The obtained results indicate that a layer of dry pumices may induce lateral redistribution of water through the overlying ashes. In steep sloping deposits, this may favor the establishment of downslope directed subsurface runoff, which drains part of the infiltrating water towards the toe of the slope. In real slopes, depending on local morphology, such a downslope flow may have a beneficial effect on slope stability, as some water is drained out of the slope, or may even contribute to the establishment of triggering conditions, as it can result in flow concentration leading to local failure.

Effect of Ag as a surfactant on the thermal stability in Cu/Co multilayers

NASA Astrophysics Data System (ADS)

Gupta, M.; Gupta, A.; Amir, S. M.; Stahn, J.; Zegenhagen, J.

2010-02-01

In the present work we studied the effect of Ag as a surfactant in Cu/Co multilayers prepared by ion beam sputtering. Two identical samples of Cu/Co multilayers with 0.2nm Ag on a Cu buffer layer and without this Ag layer were deposited on Si substrates. It is known that Cu has a lower free energy than Co, and therefore, the Cu/Co interfaces are not symmetric. Addition of Ag alters the kinetics and thermodynamics of the growth and triggers the layer by layer growth as Ag floats on the growing front balancing the surface free energy of Cu and Co. It was found that with addition of Ag surfactant the thermal stability of Cu/Co multilayer improves.

Climatic Signals from Intra-annual Density Fluctuation Frequency in Mediterranean Pines at a Regional Scale

PubMed Central

Zalloni, Enrica; de Luis, Martin; Campelo, Filipe; Novak, Klemen; De Micco, Veronica; Di Filippo, Alfredo; Vieira, Joana; Nabais, Cristina; Rozas, Vicente; Battipaglia, Giovanna

2016-01-01

Tree rings provide information about the climatic conditions during the growing season by recording them in different anatomical features, such as intra-annual density fluctuations (IADFs). IADFs are intra-annual changes of wood density appearing as latewood-like cells within earlywood, or earlywood-like cells within latewood. The occurrence of IADFs is dependent on the age and size of the tree, and it is triggered by climatic drivers. The variations of IADF frequency of different species and their dependence on climate across a wide geographical range have still to be explored. The objective of this study is to investigate the effect of age, tree-ring width and climate on IADF formation and frequency at a regional scale across the Mediterranean Basin in Pinus halepensis Mill., Pinus pinaster Ait., and Pinus pinea L. The analyzed tree-ring network was composed of P. pinea trees growing at 10 sites (2 in Italy, 4 in Spain, and 4 in Portugal), P. pinaster from 19 sites (2 in Italy, 13 in Spain, and 4 in Portugal), and P. halepensis from 38 sites in Spain. The correlations between IADF frequency and monthly minimum, mean and maximum temperatures, as well as between IADF frequency and total precipitation, were analyzed. A significant negative relationship between IADF frequency and tree-ring age was found for the three Mediterranean pines. Moreover, IADFs were more frequent in wider rings than in narrower ones, although the widest rings showed a reduced IADF frequency. Wet conditions during late summer/early autumn triggered the formation of IADFs in the three species. Our results suggest the existence of a common climatic driver for the formation of IADFs in Mediterranean pines, highlighting the potential use of IADF frequency as a proxy for climate reconstructions with geographical resolution. PMID:27200052

Reactive power compensator

DOEpatents

El-Sharkawi, Mohamed A.; Venkata, Subrahmanyam S.; Chen, Mingliang; Andexler, George; Huang, Tony

1992-01-01

A system and method for determining and providing reactive power compensation for an inductive load. A reactive power compensator (50,50') monitors the voltage and current flowing through each of three distribution lines (52a, 52b, 52c), which are supplying three-phase power to one or more inductive loads. Using signals indicative of the current on each of these lines when the voltage waveform on the line crosses zero, the reactive power compensator determines a reactive power compensator capacitance that must be connected to the lines to maintain a desired VAR level, power factor, or line voltage. Alternatively, an operator can manually select a specific capacitance for connection to each line, or the capacitance can be selected based on a time schedule. The reactive power compensator produces control signals, which are coupled through optical fibers (102/106) to a switch driver (110, 110') to select specific compensation capacitors (112) for connections to each line. The switch driver develops triggering signals that are supplied to a plurality of series-connected solid state switches (350), which control charge current in one direction in respect to ground for each compensation capacitor. During each cycle, current flows from ground to charge the capacitors as the voltage on the line begins to go negative from its positive peak value. The triggering signals are applied to gate the solid state switches into a conducting state when the potential on the lines and on the capacitors reaches a negative peak value, thereby minimizing both the potential difference and across the charge current through the switches when they begin to conduct. Any harmonic distortion on the potential and current carried by the lines is filtered out from the current and potential signals used by the reactive power compensator so that it does not affect the determination of the required reactive compensation.

Reactive Power Compensator.

DOEpatents

El-Sharkawi, M.A.; Venkata, S.S.; Chen, M.; Andexler, G.; Huang, T.

1992-07-28

A system and method for determining and providing reactive power compensation for an inductive load. A reactive power compensator (50,50') monitors the voltage and current flowing through each of three distribution lines (52a, 52b, 52c), which are supplying three-phase power to one or more inductive loads. Using signals indicative of the current on each of these lines when the voltage waveform on the line crosses zero, the reactive power compensator determines a reactive power compensator capacitance that must be connected to the lines to maintain a desired VAR level, power factor, or line voltage. Alternatively, an operator can manually select a specific capacitance for connection to each line, or the capacitance can be selected based on a time schedule. The reactive power compensator produces control signals, which are coupled through optical fibers (102/106) to a switch driver (110, 110') to select specific compensation capacitors (112) for connections to each line. The switch driver develops triggering signals that are supplied to a plurality of series-connected solid state switches (350), which control charge current in one direction in respect to ground for each compensation capacitor. During each cycle, current flows from ground to charge the capacitors as the voltage on the line begins to go negative from its positive peak value. The triggering signals are applied to gate the solid state switches into a conducting state when the potential on the lines and on the capacitors reaches a negative peak value, thereby minimizing both the potential difference and across the charge current through the switches when they begin to conduct. Any harmonic distortion on the potential and current carried by the lines is filtered out from the current and potential signals used by the reactive power compensator so that it does not affect the determination of the required reactive compensation. 26 figs.

Logical enzyme triggered (LET) layer-by-layer nanocapsules for drug delivery system

NASA Astrophysics Data System (ADS)

Kelley, Marie-Michelle

Breast cancer is the second leading cause of morbidity and mortality among women in the United States. Early detection and treatment methods have resulted in 100% 5-year survival rates for stage 0-I breast cancer. Unfortunately, the 5-year survival rate of metastatic breast cancer (stage IV) is reduced fivefold. The most challenging issues of metastatic breast cancer treatment are the ability to selectively target the adenoma and adenocarcinoma cells both in their location of origin and as they metastasize following initial treatment. Multilayer/Layer-by-Layer (LbL) nanocapsules have garnered vast interest as anticancer drug delivery systems due to their ability to be easily modified, their capacity to encapsulate a wide range of chemicals and proteins, and their improved pharmacokinetics. Multilayer nanocapsule formation requires the layering of opposing charged polyelectrolytic polymers over a removable core nanoparticle. Our goal is to have a programmable nanocapsules degrade only after receiving and validating specific breast cancer biomarkers. The overall objective is to fabricate a novel programmable LbL nanocapsule with a specific logical system that will enhance functions pertinent to drug delivery systems. Our central hypothesis is that LbL technology coupled with extracellular matrix (ECM) protein substrates will result in a logical enzyme triggered LbL nanocapsule drug delivery system. This platform represents a novel approach toward a logically regulated nano-encapsulated cancer therapy that can selectively follow and deliver chemotherapeutics to cancer cells. The rationale for this project is to overcome a crucial limitation of existing drug delivery systems where chemotherapeutic can be erroneously delivered to non-carcinogenic cells.

Field coupling-induced pattern formation in two-layer neuronal network

NASA Astrophysics Data System (ADS)

Qin, Huixin; Wang, Chunni; Cai, Ning; An, Xinlei; Alzahrani, Faris

2018-07-01

The exchange of charged ions across membrane can generate fluctuation of membrane potential and also complex effect of electromagnetic induction. Diversity in excitability of neurons induces different modes selection and dynamical responses to external stimuli. Based on a neuron model with electromagnetic induction, which is described by magnetic flux and memristor, a two-layer network is proposed to discuss the pattern control and wave propagation in the network. In each layer, gap junction coupling is applied to connect the neurons, while field coupling is considered between two layers of the network. The field coupling is approached by using coupling of magnetic flux, which is associated with distribution of electromagnetic field. It is found that appropriate intensity of field coupling can enhance wave propagation from one layer to another one, and beautiful spatial patterns are formed. The developed target wave in the second layer shows some difference from target wave triggered in the first layer of the network when two layers are considered by different excitabilities. The potential mechanism could be pacemaker-like driving from the first layer will be encoded by the second layer.

Energetic composites and method of providing chemical energy

DOEpatents

Danen, Wayne C.; Martin, Joe A.

1997-01-01

A method for providing chemical energy and energetic compositions of matter consisting of thin layers of substances which will exothermically react with one another. The layers of reactive substances are separated by thin layers of a buffer material which prevents the reactions from taking place until the desired time. The reactions are triggered by an external agent, such as mechanical stress or an electric spark. The compositions are known as metastable interstitial composites (MICs). This class of compositions includes materials which have not previously been capable of use as energetic materials. The speed and products of the reactions can be varied to suit the application.

Energetic composites and method of providing chemical energy

DOEpatents

Danen, W.C.; Martin, J.A.

1997-02-25

A method is described for providing chemical energy and energetic compositions of matter consisting of thin layers of substances which will exothermically react with one another. The layers of reactive substances are separated by thin layers of a buffer material which prevents the reactions from taking place until the desired time. The reactions are triggered by an external agent, such as mechanical stress or an electric spark. The compositions are known as metastable interstitial composites (MICs). This class of compositions includes materials which have not previously been capable of use as energetic materials. The speed and products of the reactions can be varied to suit the application. 3 figs.

Friction-Induced Changes in the Surface Structure of Basalt and Granite

NASA Astrophysics Data System (ADS)

Vettegren, V. I.; Arora, K.; Ponomarev, A. V.; Mamalimov, R. I.; Shcherbakov, I. P.; Kulik, V. B.

2018-05-01

Friction-induced changes in the structure of the surface layer of basalt and granite samples extracted from a well in the triggered seismicity zone in the Koyna-Warna region, India, have been studied by infrared, Raman, and photoluminescence spectroscopy. It has been found that friction leads to a partial degradation of quartz, albite, and clinopyroxenes crystals. Instead of these crystals, a thin layer of a mineral with a low coefficient of friction—kaolinite—is formed on the surface.

Globalization, marine regime shifts and the Soviet Union

PubMed Central

Österblom, Henrik; Folke, Carl

2015-01-01

Regime shifts have been observed in marine ecosystems around the world, with climate and fishing suggested as major drivers of such shifts. The global and regional dynamics of the climate system have been studied in this context, and efforts to develop an analogous understanding of fishing activities are developing. Here, we investigate the timing of pelagic marine regime shifts in relation to the emergence of regional and global fishing activities of the Soviet Union. Our investigation of official catch statistics reflects that the Soviet Union was a major fishing actor in all large marine ecosystems where regime shifts have been documented, including in ecosystems where overfishing has been established as a key driver of these changes (in the Baltic and Black Seas and the Scotian Shelf). Globalization of Soviet Union fishing activities pushed exploitation to radically new levels and triggered regional and global governance responses for improved management. Since then, exploitation levels have remained and increased with new actors involved. Based on our exploratory work, we propose that a deeper understanding of the role of global fishing actors is central for improved management of marine ecosystems.

Decaying and decayless transverse oscillations of a coronal loop

NASA Astrophysics Data System (ADS)

Nisticò, G.; Nakariakov, V. M.; Verwichte, E.

2013-04-01

Aims: We investigate kink oscillations of loops observed in an active region with the Atmospheric Imaging Assembly (AIA) instrument on board the Solar Dynamics Observatory (SDO) spacecraft before and after a flare. Methods: The oscillations were depicted and analysed with time-distance maps, extracted from the cuts taken parallel or perpendicular to the loop axis. Moving loops were followed in time with steadily moving slits. The period of oscillations and its time variation were determined by best-fitting harmonic functions. Results: We show that before and well after the occurrence of the flare, the loops experience low-amplitude decayless oscillations. The flare and the coronal mass ejection associated to it trigger large-amplitude oscillations that decay exponentially in time. The periods of the kink oscillations in both regimes (about 240 s) are similar. An empirical model of the phenomenon in terms of a damped linear oscillator excited by a continuous low-amplitude harmonic driver and by an impulsive high-amplitude driver is found to be consistent with the observations. Two movies are available in electronic form at http://www.aanda.org

A late and failure of airbag deployment case study for drivers of passenger cars in rear-end collisions

NASA Astrophysics Data System (ADS)

Toganel, George-Radu; Ovidiu Soica, Adrian

2017-10-01

The presented study was directed at two types of airbag miss-deployments: late deployment and non-deployment. Late deployment can be a product of override or underride road traffic accidents. Non-deployment can be a product of technical failure or trigger algorithm’s inability to correctly assume the state of the accident to happen. In order to analyse the phenomena through physical tests, a specialized test device was used for a series of 8 non-deployment tests and a series of 4 airbag firing tests, totalling 12 tests. Acceleration based data was recorded and analysed for the movement of the device part simulating the driver head. High speed video recording was used to analyse the mechanics of airbag deployment and correlate with the acceleration based data. It has been determined, in the limitations of the laboratory testing environment, a significant variation of the time frame for the airbag deployments, despite using similar testing conditions and identical tested products. Also, the initial time frame for airbag deployment delay was overshadowed by other factors such as time to impact.

Compact sub-nanosecond pulse seed source with diode laser driven by a high-speed circuit

NASA Astrophysics Data System (ADS)

Wang, Xiaoqian; Wang, Bo; Wang, Junhua; Cheng, Wenyong

2018-06-01

A compact sub-nanosecond pulse seed source with 1550 nm diode laser (DL) was obtained by employing a high-speed circuit. The circuit mainly consisted of a short pulse generator and a short pulse driver. The short pulse generator, making up of a complex programmable logic device (CPLD), a level translator, two programmable delay chips and an AND gate chip, output a triggering signal to control metal-oxide-semiconductor field-effect transistor (MOSFET) switch of the short pulse driver. The MOSFET switch with fast rising time and falling time both shorter than 1 ns drove the DL to emit short optical pulses. Performances of the pulse seed source were tested. The results showed that continuously adjustable repetition frequency ranging from 500 kHz to 100 MHz and pulse duration in the range of 538 ps to 10 ns were obtained, respectively. 537 μW output was obtained at the highest repetition frequency of 100 MHz with the shortest pulse duration of 538 ps. These seed pulses were injected into an fiber amplifier, and no optical pulse distortions were found.

Full-color reflective cholesteric liquid crystal display

NASA Astrophysics Data System (ADS)

Huang, Xiao-Yang; Khan, Asad A.; Davis, Donald J.; Podojil, Gregg M.; Jones, Chad M.; Miller, Nick; Doane, J. William

1999-03-01

We report a full color 1/4 VGA reflective cholesteric display with 4096 colors. The display can deliver a brightness approaching 40 percent reflected luminance, far exceeding all other reflective technologies. With its zero voltage bistability, images can be stored for days and months without ny power consumption. This property can significantly extend the battery life. The capability of displaying full color complex graphics and images is a must in order to establish a market position in this multimedia age. Color is achieved by stacking RGB cells. The top layer is blue with right chirality, the middle layer is green with left chirality, and the bottom layer is red with right chirality. The choice of opposite chirality prevents the loss in the green and red spectra from the blue layer on the top. We also adjusted the thickness of each layer to achieve color balance. We implement gray scale in each layer with pulse width modulation. This modulation method is the best choice consideration of lower driver cost, simpler structure with fewer cross talk problems. Various drive schemes and modulation methods will be discussed in the conference.

Relaxation of an unsteady turbulent boundary layer on a flat plate in an expansion tube

NASA Technical Reports Server (NTRS)

Gurta, R. N.; Trimpi, R. L.

1974-01-01

An analysis is presented for the relaxation of a turbulent boundary layer on a semi-infinite flat plate after passage of a shock wave and a trailing driver gas-driven gas interface. The problem has special application to expansion-tube flows. The flow-governing equations have been transformed into the Crocco variables, and a time-similar solution is presented in terms of the dimensionless distance-time variable alpha and the dimensionless velocity variable beta. An eddy-viscosity model, similar to that of time-steady boundary layers, is applied to the inner and outer regions of the boundary layer. A turbulent Prandtl number equal to the molecular Prandtl number is used to relate the turbulent heat flux to the eddy viscosity. The numerical results, obtained by using the Gauss-Seidel line-relaxation method, indicate that a fully turbulent boundary layer relaxes faster to the final steady-state values of heat transfer and skin friction than a laminar boundary layer. The results also give a fairly good estimate of the local skin friction and heat transfer for near steady-flow conditions.

Strong Motion Seismograph Based On MEMS Accelerometer

NASA Astrophysics Data System (ADS)

Teng, Y.; Hu, X.

2013-12-01

The MEMS strong motion seismograph we developed used the modularization method to design its software and hardware.It can fit various needs in different application situation.The hardware of the instrument is composed of a MEMS accelerometer,a control processor system,a data-storage system,a wired real-time data transmission system by IP network,a wireless data transmission module by 3G broadband,a GPS calibration module and power supply system with a large-volumn lithium battery in it. Among it,the seismograph's sensor adopted a three-axis with 14-bit high resolution and digital output MEMS accelerometer.Its noise level just reach about 99μg/√Hz and ×2g to ×8g dynamically selectable full-scale.Its output data rates from 1.56Hz to 800Hz. Its maximum current consumption is merely 165μA,and the device is so small that it is available in a 3mm×3mm×1mm QFN package. Furthermore,there is access to both low pass filtered data as well as high pass filtered data,which minimizes the data analysis required for earthquake signal detection. So,the data post-processing can be simplified. Controlling process system adopts a 32-bit low power consumption embedded ARM9 processor-S3C2440 and is based on the Linux operation system.The processor's operating clock at 400MHz.The controlling system's main memory is a 64MB SDRAM with a 256MB flash-memory.Besides,an external high-capacity SD card data memory can be easily added.So the system can meet the requirements for data acquisition,data processing,data transmission,data storage,and so on. Both wired and wireless network can satisfy remote real-time monitoring, data transmission,system maintenance,status monitoring or updating software.Linux was embedded and multi-layer designed conception was used.The code, including sensor hardware driver,the data acquisition,earthquake setting out and so on,was written on medium layer.The hardware driver consist of IIC-Bus interface driver, IO driver and asynchronous notification driver. The application program layer mainly concludes: earthquake parameter module, local database managing module, data transmission module, remote monitoring, FTP service and so on. The application layer adopted multi-thread process. The whole strong motion seismograph was encapsulated in a small aluminum box, which size is 80mm×120mm×55mm. The inner battery can work continuesly more than 24 hours. The MEMS accelerograph uses modular design for its software part and hardware part. It has remote software update function and can meet the following needs: a) Auto picking up the earthquake event; saving the data on wave-event files and hours files; It may be used for monitoring strong earthquake, explosion, bridge and house health. b) Auto calculate the earthquake parameters, and transferring those parameters by 3G wireless broadband network. This kind of seismograph has characteristics of low cost, easy installation. They can be concentrated in the urban region or areas need to specially care. We can set up a ground motion parameters quick report sensor network while large earthquake break out. Then high-resolution-fine shake-map can be easily produced for the need of emergency rescue. c) By loading P-wave detection program modules, it can be used for earthquake early warning for large earthquakes; d) Can easily construct a high-density layout seismic monitoring network owning remote control and modern intelligent earthquake sensor.

Holocene earthquake-triggered turbidites from the Saguenay (Eastern Canada) and Reloncavi (Chilean margin) fjords

NASA Astrophysics Data System (ADS)

St-Onge, Guillaume; Chapron, Emmanuel; Mulsow, Sandor; Salas, Marcos; Debret, Maxime; Foucher, Anthony; Mulder, Thierry; Desmet, Marc; Costa, Pedro; Ghaleb, Bassam; Locat, Jacques

2013-04-01

Fjords are unique archives of climatic and environmental changes, but also of natural hazards. They can preserve thick sedimentary sequences deposited under very high sediment accumulation rates, making them ideally suited to record historical and pre-historical sedimentological events such as major landslides, floods or earthquakes. In fact, by carefully characterizing and dating the sediments and by comparing the basin fill seismic stratigraphy and sedimentary records with historical events, it is possible to "calibrate" recent rapidly deposited layers such as turbidites with a trigger mechanism and extend these observations further back in time by using seismic reflection profiles and longer sediment cores. Here, we will compare earthquake-triggered turbidites in fjords from the Southern and Northern Hemispheres: the Saguenay (Eastern Canada) and Reloncavi fjords (southern Chilean margin). In both settings, we will first look at basin fill geometries and at the sedimentological properties of historical events before extending the records further back in time. In both fjords, several turbidites were associated with large magnitude historic and pre-historic earthquakes including the 1663 AD (M>7) earthquake in the Saguenay Fjord, and the 1960 (M 9.5), 1837 (M~8) and 1575 AD major Chilean subduction earthquakes in the Reloncavi Fjord. In addition, a sand layer with sea urchin fragments and the exoscopic characteristics typical of a tsunami deposit was observed immediately above the turbidite associated with the 1575 AD earthquake in the Reloncavi Fjord and supports both the chronology and the large magnitude of that historic earthquake. In both fjords, as well as in other recently recognized earthquake-triggered turbidites, the decimeter-to meter-thick normally-graded turbidites are characterized by a homogeneous, but slightly fining upward tail. Finally, new radiocarbon results will be presented and indicate that at least 19 earthquake-triggered turbidites were recorded in the Reloncavi Fjord during the last 7500 cal BP.

Role of zonal flow predator-prey oscillations in triggering the transition to H-mode confinement.

PubMed

Schmitz, L; Zeng, L; Rhodes, T L; Hillesheim, J C; Doyle, E J; Groebner, R J; Peebles, W A; Burrell, K H; Wang, G

2012-04-13

Direct evidence of zonal flow (ZF) predator-prey oscillations and the synergistic roles of ZF- and equilibrium E×B flow shear in triggering the low- to high-confinement (L- to H-mode) transition in the DIII-D tokamak is presented. Periodic turbulence suppression is first observed in a narrow layer at and just inside the separatrix when the shearing rate transiently exceeds the turbulence decorrelation rate. The final transition to H mode with sustained turbulence and transport reduction is controlled by equilibrium E×B shear due to the increasing ion pressure gradient.

Pulsed laser triggered high speed microfluidic fluorescence activated cell sorter†‡

PubMed Central

Wu, Ting-Hsiang; Chen, Yue; Park, Sung-Yong; Hong, Jason; Teslaa, Tara; Zhong, Jiang F.; Di Carlo, Dino; Teitell, Michael A.

2014-01-01

We report a high speed and high purity pulsed laser triggered fluorescence activated cell sorter (PLACS) with a sorting throughput up to 20 000 mammalian cells s−1 with 37% sorting purity, 90% cell viability in enrichment mode, and >90% purity in high purity mode at 1500 cells s−1 or 3000 beads s−1. Fast switching (30 μs) and a small perturbation volume (~90 pL) is achieved by a unique sorting mechanism in which explosive vapor bubbles are generated using focused laser pulses in a single layer microfluidic PDMS channel. PMID:22361780

Ionospheric Change and Solar EUV Irradiance

NASA Astrophysics Data System (ADS)

Sojka, J. J.; David, M.; Jensen, J. B.; Schunk, R. W.

2011-12-01

The ionosphere has been quantitatively monitored for the past six solar cycles. The past few years of observations are showing trends that differ from the prior cycles! Our good statistical relationships between the solar radio flux index at 10.7 cm, the solar EUV Irradiance, and the ionospheric F-layer peak density are showing indications of divergence! Present day discussion of the Sun-Earth entering a Dalton Minimum would suggest change is occurring in the Sun, as the driver, followed by the Earth, as the receptor. The dayside ionosphere is driven by the solar EUV Irradiance. But different components of this spectrum affect the ionospheric layers differently. For a first time the continuous high cadence EUV spectra from the SDO EVE instrument enable ionospheric scientists the opportunity to evaluate solar EUV variability as a driver of ionospheric variability. A definitive understanding of which spectral components are responsible for the E- and F-layers of the ionosphere will enable assessments of how over 50 years of ionospheric observations, the solar EUV Irradiance has changed. If indeed the evidence suggesting the Sun-Earth system is entering a Dalton Minimum periods is correct, then the comprehensive EVE solar EUV Irradiance data base combined with the ongoing ionospheric data bases will provide a most fortuitous fiduciary reference baseline for Sun-Earth dependencies. Using the EVE EUV Irradiances, a physics based ionospheric model (TDIM), and 50 plus years of ionospheric observation from Wallops Island (Virginia) the above Sun-Earth ionospheric relationship will be reported on.

Annually laminated lake sediments as recorders of flood events: evidence from combining monitoring and calibration

NASA Astrophysics Data System (ADS)

Kämpf, Lucas; Brauer, Achim; Mueller, Philip; Güntner, Andreas; Merz, Bruno

2015-04-01

The relation of changing climate and the occurrence of strong flood events has been controversially debated over the last years. One major limitation in this respect is the temporal extension of instrumental flood time series, rarely exceeding 50-100 years, which is too short to reflect the full range of natural climate variability in a region. Therefore, geoarchives are increasingly explored as natural flood recorders far beyond the range of instrumental flood time series. Annually laminated (varved) lake sediments provide particularly valuable archives since (i) lakes form ideal traps in the landscape continuously recording sediment flux from the catchment and (ii) individual flood events are recorded as detrital layers and can be dated with seasonal precision by varve counting. Despite the great potential of varved lake sediments for reconstructing long flood time series, there are still some confinements with respect to their interpretation due to a lack in understanding processes controlling the formation of detrital layers. For this purpose, we investigated the formation of detrital flood layers in Lake Mondsee (Upper Austria) in great detail by monitoring flood-related sediment flux and comparing detrital layers in sub-recent sediments with river runoff data. Sediment flux at the lake bottom was trapped over a three-year period (2011-2013) at two locations in Lake Mondsee, one located 0.9 km off the main inflow (proximal) and one in a more distal position at a distance of 2.8 km. The monitoring data include 26 floods of different amplitude (max. hourly discharge=10-110 cbm/s) which triggered variable fluxes of catchment sediment to the lake floor (4-760 g/(sqm*d)). The comparison of runoff and sediment data revealed empiric runoff thresholds for triggering significant detrital sediment influx to the proximal (20 cbm/s) and distal lake basin (30 cbm/s) and an exponential relation between runoff amplitude and the amount of deposited sediment. A succession of 20 sub-millimetre to maximum 8 mm thick flood-triggered detrital layers, deposited between 1976 and 2005, was detected in two varved surface sediment cores from the same locations as the sediment traps. Calibration of the detrital layer record with river runoff data revealed empirical thresholds for flood layer deposition. These thresholds are higher than those for trapped sediment flux but, similarly to the trap results, increasing from the proximal (50-60 cbm/s; daily mean=40 cbm/s) to the distal lake basin (80 cbm/s, 2 days>40 cbm/s). Three flood events above the threshold for detrital layer formation in the proximal and one in the distal lake basin were also recorded in the monitoring period. These events resulted in exceptional sediment transfer to the lake of more than 400 g/sqm at both sites, which is therefore interpreted as the minimum sediment amount for producing a visible detrital layer.

The cytoskeleton is disrupted by the bacterial effector HrpZ, but not by the bacterial PAMP flg22, in tobacco BY-2 cells.

PubMed

Guan, Xin; Buchholz, Günther; Nick, Peter

2013-04-01

Plant innate immunity is composed of two layers. Basal immunity is triggered by pathogen-associated molecular patterns (PAMPs) such as the flagellin-peptide flg22 and is termed PAMP-triggered immunity (PTI). In addition, effector-triggered immunity (ETI) linked with programmed cell death and cytoskeletal reorganization can be induced by pathogen-derived factors, such as the Harpin proteins originating from phytopathogenic bacteria. To get insight into the link between cytoskeleton and PTI or ETI, this study followed the responses of actin filaments and microtubules to flg22 and HrpZ in vivo by spinning-disc confocal microscopy in GFP-tagged marker lines of tobacco BY-2. At a concentration that clearly impairs mitosis, flg22 can induce only subtle cytoskeletal responses. In contrast, HrpZ causes a rapid and massive bundling of actin microfilaments (completed in ~20 min, i.e. almost simultaneously with extracellular alkalinization), which is followed by progressive disintegration of actin cables and cytoplasmic microtubules, a loss of cytoplasmic structure, and vacuolar disintegration. Cytoskeletal disruption is proposed as an early event that discriminates HrpZ-triggered ETI-like defence from flg22-triggered PTI.

The cytoskeleton is disrupted by the bacterial effector HrpZ, but not by the bacterial PAMP flg22, in tobacco BY-2 cells

PubMed Central

Guan, Xin; Buchholz, Günther; Nick, Peter

2013-01-01

Plant innate immunity is composed of two layers. Basal immunity is triggered by pathogen-associated molecular patterns (PAMPs) such as the flagellin-peptide flg22 and is termed PAMP-triggered immunity (PTI). In addition, effector-triggered immunity (ETI) linked with programmed cell death and cytoskeletal reorganization can be induced by pathogen-derived factors, such as the Harpin proteins originating from phytopathogenic bacteria. To get insight into the link between cytoskeleton and PTI or ETI, this study followed the responses of actin filaments and microtubules to flg22 and HrpZ in vivo by spinning-disc confocal microscopy in GFP-tagged marker lines of tobacco BY-2. At a concentration that clearly impairs mitosis, flg22 can induce only subtle cytoskeletal responses. In contrast, HrpZ causes a rapid and massive bundling of actin microfilaments (completed in ~20min, i.e. almost simultaneously with extracellular alkalinization), which is followed by progressive disintegration of actin cables and cytoplasmic microtubules, a loss of cytoplasmic structure, and vacuolar disintegration. Cytoskeletal disruption is proposed as an early event that discriminates HrpZ-triggered ETI-like defence from flg22-triggered PTI. PMID:23408828

Phreatic eruptions and deformation of Ioto Island (Iwo-jima), Japan, triggered by deep magma injection

NASA Astrophysics Data System (ADS)

Ueda, Hideki; Nagai, Masashi; Tanada, Toshikazu

2018-03-01

On Ioto Island (Iwo-jima), 44 phreatic eruptions have been recorded since 1889, when people began to settle there. Four of these eruptions, after the beginning of continuous observation by seismometers in 1976, were accompanied by intense seismic activity and rapid crustal deformation beforehand. Other eruptions on Ioto were without obvious crustal activities. In this paper, we discuss the mechanisms of phreatic eruptions on Ioto. Regular geodetic surveys and continuous GNSS observations show that Ioto intermittently uplifts at an abnormally high rate. All of the four eruptions accompanied by the precursors took place during intermittent uplifts. The crustal deformation before and after one of these eruptions revealed that a sill-like deformation source in the shallow part of Motoyama rapidly inflated before and deflated after the beginning of the eruption. From the results of a seismic array and a borehole survey, it is estimated that there is a layer of lava at a depth of about 100-200 m, and there is a tuff layer about 200-500 m beneath it. The eruptions accompanied by the precursors probably occurred due to abrupt boiling of hot water in hydrothermal reservoirs in the tuff layer, sealed by the lava layer and triggered by intermittent uplift. For the eruptions without precursors, the hydrothermal systems are weakly sealed by clay or probably occurred on the same principle as a geyser because phreatic eruptions had occurred beforehand and hydrostatic pressure is applied to the hydrothermal reservoirs.

Shallow convection on day 261 of GATE - Mesoscale arcs

NASA Technical Reports Server (NTRS)

Warner, C.; Simpson, J.; Martin, D. W.; Suchman, D.; Mosher, F. R.; Reinking, R. F.

1979-01-01

Cloudy convection in the moist layer of a cloud cluster growing in the GATE ship array is examined. Analyses suggest that the moist layer was dominated by features of horizontal dimension roughly 40 km and lifetime roughly 2 h, with arc patterns triggered by dense downdraft air accompanying rainfall, and composed of many small cumulus clouds. Aircraft recorded data on thermodynamic quantities and winds, indicating that the arcs persisted as mesoscale circulations driven by the release of latent heat in the clouds, rather than being driven by the original density current at the surface. It is also suggested that the mesoscale cloud patterns of the moist layer play a primary role in heat transfer upward within this layer, and contribute to the forcing of showering midtropospheric clouds.

Dual-Polarization Radar Observations of Upward Lightning-Producing Storms

NASA Astrophysics Data System (ADS)

Lueck, R.; Helsdon, J. H.; Warner, T.

2013-12-01

The Upward Lightning Triggering Study (UPLIGHTS) seeks to determine how upward lightning, which originates from the tips of tall objects, is triggered by nearby flash activity. As a component of this study we analyze standard and dual-polarization weather radar data. The Correlation Coefficient (CC) in particular can be used to identify and quantify the melting layer associated with storms that produce upward lightning. It has been proposed that positive charge generation due to aggregate shedding at the melting layer results in a positive charge region just above the cloud base. This positive charge region may serve as a positive potential well favorable for negative leader propagation, which initiate upward positive leaders from tall objects. We characterize the horizontal coverage, thickness and height of the melting layer in addition to cloud base heights when upward lightning occurs to determine trends and possible threshold criteria relating to upward lightning production. Furthermore, we characterize storm type and morphology using relevant schemes as well as precipitation type using the Hydrometer Classification Algorithm (HCA) for upward lightning-producing storms. Ice-phase hydrometeors have been shown to be a significant factor in thunderstorm electrification. Only a small fraction of storms produce upward lightning, so null cases will be examined and compared as well.

Collision avoidance using neural networks

NASA Astrophysics Data System (ADS)

Sugathan, Shilpa; Sowmya Shree, B. V.; Warrier, Mithila R.; Vidhyapathi, C. M.

2017-11-01

Now a days, accidents on roads are caused due to the negligence of drivers and pedestrians or due to unexpected obstacles that come into the vehicle’s path. In this paper, a model (robot) is developed to assist drivers for a smooth travel without accidents. It reacts to the real time obstacles on the four critical sides of the vehicle and takes necessary action. The sensor used for detecting the obstacle was an IR proximity sensor. A single layer perceptron neural network is used to train and test all possible combinations of sensors result by using Matlab (offline). A microcontroller (ARM Cortex-M3 LPC1768) is used to control the vehicle through the output data which is received from Matlab via serial communication. Hence, the vehicle becomes capable of reacting to any combination of real time obstacles.

Debris flows associated with the 2015 Gorkha Earthquake in Nepal

NASA Astrophysics Data System (ADS)

Dahlquist, M. P.; West, A. J.; Martinez, J.

2017-12-01

Debris flows are a primary driver of erosion and a major geologic hazard in many steep landscapes, particularly near the headwaters of rivers, and are generated in large numbers by extreme events. The 2015 Mw 7.8 Gorkha Earthquake triggered 25,000 coseismic landslides in central Nepal. During the ensuing monsoon, sediment delivered to channels by landslides was mobilized in the heavy rains, and new postseismic landslides were triggered in rock weakened by the shaking. These coseismic and postseismic landslide-generated debris flows form a useful dataset for studying the impact and behavior of debris flows on one of the most active landscapes on Earth. Debris flow-dominated channel reaches are generally understood to have a topographic signature recognizable in slope-area plots and distinct from fluvial channels, but in examining debris flows associated with the Gorkha earthquake we find they frequently extend into reaches with geometry typically associated with fluvial systems. We examine a dataset of these debris flows, considering whether they are generated by coseismic or postseismic landslides, whether they are likely to be driving active incision into bedrock, and whether their channels correspond with those typically associated with debris flows. Preliminary analysis of debris flow channels in Nepal suggests there may be systematic differences in the geometry of channels containing debris flows triggered by coseismic versus postseismic landslides, which potentially holds implications for hazard analyses and the mechanics behind the different debris flow types.

Magnetically triggered release of molecular cargo from iron oxide nanoparticle loaded microcapsules

NASA Astrophysics Data System (ADS)

Carregal-Romero, Susana; Guardia, Pablo; Yu, Xiang; Hartmann, Raimo; Pellegrino, Teresa; Parak, Wolfgang J.

2014-12-01

Photothermal release of cargo molecules has been extensively studied for bioapplications. For instance, microcapsules decorated with plasmonic nanoparticles have been widely used in in vitro assays. However, some concerns about their suitability for some in vivo applications cannot be easily overcome, in particular the limited penetration depth of light (even infrared). Magnetic nanoparticles are alternative heat-mediators for local heating, which can be triggered by applying an alternating magnetic field (AMF). AMFs are much less absorbed by tissue than light and thus can penetrate deeper overcoming the above mentioned limitations. Here we present iron oxide nanocube-modified microcapsules as a platform for magnetically triggered molecular release. Layer-by-layer assembled polyelectrolyte microcapsules with 4.6 μm diameter, which had 18 nm diameter iron oxide nanocubes integrated in their walls, were synthesized. The microcapsules were further loaded with an organic fluorescent polymer (Cascade Blue-labelled dextran), which was used as a model of molecular cargo. Through an AMF the magnetic nanoparticles were able to heat their surroundings and destroy the microcapsule walls, leading to a final release of the embedded cargo to the surrounding solution. The cargo release was monitored in solution by measuring the increase in both absorbance and fluorescence signal after the exposure to an AMF. Our results demonstrate that magnetothermal release of the encapsulated material is possible using magnetic nanoparticles with a high heating performance.Photothermal release of cargo molecules has been extensively studied for bioapplications. For instance, microcapsules decorated with plasmonic nanoparticles have been widely used in in vitro assays. However, some concerns about their suitability for some in vivo applications cannot be easily overcome, in particular the limited penetration depth of light (even infrared). Magnetic nanoparticles are alternative heat-mediators for local heating, which can be triggered by applying an alternating magnetic field (AMF). AMFs are much less absorbed by tissue than light and thus can penetrate deeper overcoming the above mentioned limitations. Here we present iron oxide nanocube-modified microcapsules as a platform for magnetically triggered molecular release. Layer-by-layer assembled polyelectrolyte microcapsules with 4.6 μm diameter, which had 18 nm diameter iron oxide nanocubes integrated in their walls, were synthesized. The microcapsules were further loaded with an organic fluorescent polymer (Cascade Blue-labelled dextran), which was used as a model of molecular cargo. Through an AMF the magnetic nanoparticles were able to heat their surroundings and destroy the microcapsule walls, leading to a final release of the embedded cargo to the surrounding solution. The cargo release was monitored in solution by measuring the increase in both absorbance and fluorescence signal after the exposure to an AMF. Our results demonstrate that magnetothermal release of the encapsulated material is possible using magnetic nanoparticles with a high heating performance. Electronic supplementary information (ESI) available. See DOI: 10.1039/c4nr04055d

Review: Potential biotechnological assets related to plant immunity modulation applicable in engineering disease-resistant crops.

PubMed

Silva, Marilia Santos; Arraes, Fabrício Barbosa Monteiro; Campos, Magnólia de Araújo; Grossi-de-Sa, Maira; Fernandez, Diana; Cândido, Elizabete de Souza; Cardoso, Marlon Henrique; Franco, Octávio Luiz; Grossi-de-Sa, Maria Fátima

2018-05-01

This review emphasizes the biotechnological potential of molecules implicated in the different layers of plant immunity, including, pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI), effector-triggered susceptibility (ETS), and effector-triggered immunity (ETI) that can be applied in the development of disease-resistant genetically modified (GM) plants. These biomolecules are produced by pathogens (viruses, bacteria, fungi, oomycetes) or plants during their mutual interactions. Biomolecules involved in the first layers of plant immunity, PTI and ETS, include inhibitors of pathogen cell-wall-degrading enzymes (CWDEs), plant pattern recognition receptors (PRRs) and susceptibility (S) proteins, while the ETI-related biomolecules include plant resistance (R) proteins. The biomolecules involved in plant defense PTI/ETI responses described herein also include antimicrobial peptides (AMPs), pathogenesis-related (PR) proteins and ribosome-inhibiting proteins (RIPs), as well as enzymes involved in plant defensive secondary metabolite biosynthesis (phytoanticipins and phytoalexins). Moreover, the regulation of immunity by RNA interference (RNAi) in GM disease-resistant plants is also considered. Therefore, the present review does not cover all the classes of biomolecules involved in plant innate immunity that may be applied in the development of disease-resistant GM crops but instead highlights the most common strategies in the literature, as well as their advantages and disadvantages. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

Hypodermal delivery of cosmetic actives for improved facial skin morphology and functionality.

PubMed

Bojanowski, K

2013-12-01

Skin compartments traditionally targeted by cosmetic actives - epidermis and dermis - are anchored and nourished by the underlying hypodermis, which therefore should be a key target for skin-rejuvenating formulations. However, given the difficulty to reach even the superficial layers of the skin, and to its 'unglamorous' fatty composition, the regenerative potential of hypodermis remains largely untapped. Therefore, this study was to investigate the capacity of a cosmetic material to trigger a regenerative response in dermis and epidermis through a selective action on hypodermis. Furthermore, it aimed to establish the effect of such cosmetic material in transbuccal hypodermal delivery form, on the hypodermal precursor cells - the preadipocytes. A combination of grape seed extract and soy phospholipids was formulated and standardized for elastase activity and free radical inhibition. This formulation was then used to contact the hypodermal layer of human skin biopsies and - under a transbuccal delivery vehicle form - the 3T3-L1 preadipocytes, and its effects were quantified using PCR arrays and histochemistry. Application of the standardized grape/soy material to the hypodermal layer of skin triggered modulation of gene expression in the upper layers of the skin and resulted in the clear morphological improvement at the dermal and epidermal levels. Furthermore, when this material was formulated in a mucoadhesive, intraoral film and applied on 3T3-L1 preadipocytes, the resulting modulation of gene expression in these cells was consistent with differentiation and detoxification effects. These results suggest that transbuccal formulations of nutraceutical grade cosmetics have potential to induce signal transduction pathways in facial hypodermis, resulting in anti-aging effects throughout all skin compartments, including dermal and epidermal layers. © 2013 Society of Cosmetic Scientists and the Société Française de Cosmétologie.

m6A-Driver: Identifying Context-Specific mRNA m6A Methylation-Driven Gene Interaction Networks

PubMed Central

Zhang, Song-Yao; Zhang, Shao-Wu; Liu, Lian; Huang, Yufei

2016-01-01

As the most prevalent mammalian mRNA epigenetic modification, N6-methyladenosine (m6A) has been shown to possess important post-transcriptional regulatory functions. However, the regulatory mechanisms and functional circuits of m6A are still largely elusive. To help unveil the regulatory circuitry mediated by mRNA m6A methylation, we develop here m6A-Driver, an algorithm for predicting m6A-driven genes and associated networks, whose functional interactions are likely to be actively modulated by m6A methylation under a specific condition. Specifically, m6A-Driver integrates the PPI network and the predicted differential m6A methylation sites from methylated RNA immunoprecipitation sequencing (MeRIP-Seq) data using a Random Walk with Restart (RWR) algorithm and then builds a consensus m6A-driven network of m6A-driven genes. To evaluate the performance, we applied m6A-Driver to build the context-specific m6A-driven networks for 4 known m6A (de)methylases, i.e., FTO, METTL3, METTL14 and WTAP. Our results suggest that m6A-Driver can robustly and efficiently identify m6A-driven genes that are functionally more enriched and associated with higher degree of differential expression than differential m6A methylated genes. Pathway analysis of the constructed context-specific m6A-driven gene networks further revealed the regulatory circuitry underlying the dynamic interplays between the methyltransferases and demethylase at the epitranscriptomic layer of gene regulation. PMID:28027310

Dynamic High-Pressure Behavior of Hierarchical Heterogeneous Geological Materials

DTIC Science & Technology

2016-04-01

sandwiched between two 25µm FEP copolymer layers attached to the copper driver plate . The total package thickness with thin-film epoxy on all bonding...public release. 3 OUTLINE Page # ABSTRACT 2 1. BACKGROUND 4 2. CHARACTERISTICS OF SAND INVESTIGATED 8 3. PLATE ...constituents, phases, inter-phase boundaries ; distributions in shock states; as well as the structural evolutions which can result in strain

The competition of densification and structure ordering during crystallization of HCP-Mg in the framework of layering

NASA Astrophysics Data System (ADS)

Luo, Jie; Jiang, Yewei; Yu, Ronggang; Wu, Yongquan

2017-06-01

In this paper, we performed an NPT molecular dynamics simulation of crystallization process of HCP-Mg to probe the competition between densification and structural ordering. Two opposite layering patterns, i.e. outward and inward, were designed for analysis. From the perspective of solid-like cluster (SLC) itself, structural ordering always precedes densification; but from the perspective of SLC's precursor, structural ordering always lags behind densification; the reversion occurs at the closest two liquid layers around SLC. We call it dip-rebound phenomenon. This phenomenon is a completely new finding. It resolves, to some extent, recent debate about whether densification or structural ordering triggers crystallization.

Behavior-dependent Routing: Responding to Anomalies with Automated Low-cost Measures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oehmen, Christopher S.; Carroll, Thomas E.; Paulson, Patrick R.

2015-10-12

This is a conference paper submission describing research and software implementation of a cybersecurity concept that uses behavior models to trigger changes in routing of network traffic. As user behavior deviates more and more from baseline models, traffic is routed through more elevated layers of analysis and control.

2D Si island nucleation on the Si(111) surface at initial and late growth stages: On the role of step permeability in pyramidlike growth

NASA Astrophysics Data System (ADS)

Rogilo, D. I.; Fedina, L. I.; Kosolobov, S. S.; Ranguelov, B. S.; Latyshev, A. V.

2017-01-01

Initial and late stages of 2D Si island nucleation and growth (2DNG) on extra-large ( 100 μm) and medium size (1-10 μm) atomically flat Si(111)-(7×7) terraces bordered by step bunches have been studied by in situ REM at T =600-750 °С. At first, the layer-by-layer 2DNG takes place on whole terraces and 2D island concentration dependence on deposition rate R corresponds to critical nucleus size i =1. Continuous 2DNG triggers morphological instabilities: elongated pyramidlike waves and separate pyramids emerge on all terraces at T ≤720 °С and T =750 °С, respectively. Both instabilities arise due to the imbalance of uphill/downhill adatom currents related with large Ehrlich-Schwöbel (ES) barriers and permeability of straight [ 11 bar 2 ] -type step edges. However, the first one is initiated by dominant downhill adatom current to distant sinks: bunches, wave's step edges, and "vacancy" islands emerging on terraces due to 2D island coalescence. As a result, top layer size decreases to the critical terrace width λ where 2DNG takes place. From the analysis of λ ∝ R - χ / 2 scaling at T =650 °C, we have found that i increases from i =2 on a three-layer wave to i =6-8 on a six-layer wave. This authenticates the significance of downhill adatom sink to distant steps related to the step permeability. The second instability type at T >720 °C is related to the raising of uphill adatom current due to slightly larger ES barrier for step-up attachment comparing to the step-down one (EES- 0.9 eV [Phys. Rev. Lett. 111 (2013) 036105]). This leads to "second layer" 2D nucleation on top layers, which triggers the growth of separate pyramids. Because of small difference between ES barriers, net uphill/downhill adatom currents are nearly equivalent, and therefore layer coverage distributions of both instabilities display similar linear slopes.

GaAs photoconductive semiconductor switch

DOEpatents

Loubriel, Guillermo M.; Baca, Albert G.; Zutavern, Fred J.

1998-01-01

A high gain, optically triggered, photoconductive semiconductor switch (PCSS) implemented in GaAs as a reverse-biased pin structure with a passivation layer above the intrinsic GaAs substrate in the gap between the two electrodes of the device. The reverse-biased configuration in combination with the addition of the passivation layer greatly reduces surface current leakage that has been a problem for prior PCSS devices and enables employment of the much less expensive and more reliable DC charging systems instead of the pulsed charging systems that needed to be used with prior PCSS devices.

Linear servomotor probe drive system with real-time self-adaptive position control for the Alcator C-Mod tokamak

NASA Astrophysics Data System (ADS)

Brunner, D.; Kuang, A. Q.; LaBombard, B.; Burke, W.

2017-07-01

A new servomotor drive system has been developed for the horizontal reciprocating probe on the Alcator C-Mod tokamak. Real-time measurements of plasma temperature and density—through use of a mirror Langmuir probe bias system—combined with a commercial linear servomotor and controller enable self-adaptive position control. Probe surface temperature and its rate of change are computed in real time and used to control probe insertion depth. It is found that a universal trigger threshold can be defined in terms of these two parameters; if the probe is triggered to retract when crossing the trigger threshold, it will reach the same ultimate surface temperature, independent of velocity, acceleration, or scrape-off layer heat flux scale length. In addition to controlling the probe motion, the controller is used to monitor and control all aspects of the integrated probe drive system.

Mediodorsal Thalamic Neurons Mirror the Activity of Medial Prefrontal Neurons Responding to Movement and Reinforcement during a Dynamic DNMTP Task

PubMed Central

Miller, Rikki L.A.

2017-01-01

Abstract The mediodorsal nucleus (MD) interacts with medial prefrontal cortex (mPFC) to support learning and adaptive decision-making. MD receives driver (layer 5) and modulatory (layer 6) projections from PFC and is the main source of driver thalamic projections to middle cortical layers of PFC. Little is known about the activity of MD neurons and their influence on PFC during decision-making. We recorded MD neurons in rats performing a dynamic delayed nonmatching to position (dDNMTP) task and compared results to a previous study of mPFC with the same task (Onos et al., 2016). Criterion event-related responses were observed for 22% (254/1179) of neurons recorded in MD, 237 (93%) of which exhibited activity consistent with mPFC response types. More MD than mPFC neurons exhibited responses related to movement (45% vs. 29%) and reinforcement (51% vs. 27%). MD had few responses related to lever presses, and none related to preparation or memory delay, which constituted 43% of event-related activity in mPFC. Comparison of averaged normalized population activity and population response times confirmed the broad similarity of common response types in MD and mPFC and revealed differences in the onset and offset of some response types. Our results show that MD represents information about actions and outcomes essential for decision-making during dDNMTP, consistent with evidence from lesion studies that MD supports reward-based learning and action-selection. These findings support the hypothesis that MD reinforces task-relevant neural activity in PFC that gives rise to adaptive behavior. PMID:29034318

Mediodorsal Thalamic Neurons Mirror the Activity of Medial Prefrontal Neurons Responding to Movement and Reinforcement during a Dynamic DNMTP Task.

PubMed

Miller, Rikki L A; Francoeur, Miranda J; Gibson, Brett M; Mair, Robert G

2017-01-01

The mediodorsal nucleus (MD) interacts with medial prefrontal cortex (mPFC) to support learning and adaptive decision-making. MD receives driver (layer 5) and modulatory (layer 6) projections from PFC and is the main source of driver thalamic projections to middle cortical layers of PFC. Little is known about the activity of MD neurons and their influence on PFC during decision-making. We recorded MD neurons in rats performing a dynamic delayed nonmatching to position (dDNMTP) task and compared results to a previous study of mPFC with the same task (Onos et al., 2016). Criterion event-related responses were observed for 22% (254/1179) of neurons recorded in MD, 237 (93%) of which exhibited activity consistent with mPFC response types. More MD than mPFC neurons exhibited responses related to movement (45% vs. 29%) and reinforcement (51% vs. 27%). MD had few responses related to lever presses, and none related to preparation or memory delay, which constituted 43% of event-related activity in mPFC. Comparison of averaged normalized population activity and population response times confirmed the broad similarity of common response types in MD and mPFC and revealed differences in the onset and offset of some response types. Our results show that MD represents information about actions and outcomes essential for decision-making during dDNMTP, consistent with evidence from lesion studies that MD supports reward-based learning and action-selection. These findings support the hypothesis that MD reinforces task-relevant neural activity in PFC that gives rise to adaptive behavior.

Prediction of Rainfall-Induced Landslides

NASA Astrophysics Data System (ADS)

Nadim, F.; Sandersen, F.

2009-12-01

Rainfall-induced landslides can be triggered by two main mechanisms: shear failure due to build-up of pore water pressure and erosion by surface water runoff when flow velocity exceeds a critical value. Field measurements indicate that, in the initial phase, the slip surface of a landslide often occurs along the top of a relatively impermeable layer located at some depth within the soil profile, e.g. at the contact with a shallow underlying bedrock or parent rock. The shear strength along this surface and hence the stability of the slope is governed by the pore water pressure. The pore pressure is in turn controlled by water seepage through the slope, either from infiltrated rain, or from groundwater that follows bedrock joints and soil layers with high permeability. When the infiltration rate of the underlying layer is too low for further downward penetration of water or when a wetting front is produced, pore water pressure builds up, reducing the soil shear strength. During high intensity rainfall, surface water runoff will exert shear stresses on the bed material. De-pending on the grain size distribution and specific gravity of the material, erosion might occur when the flow velocity exceeds a critical value. As erosion progresses and sediment concentration increases, the flow regime may become unstable with heavy erosion at high flow velocity locations triggering a debris flow. In many cases, previous landslides along steep gully walls have fed an abundance of loose soil material into the gullies. Landslides along gully walls that obstruct the water transport may also trigger debris flows when the landslide-dam collapses, creating a surge downstream. Both the long-duration (1 or more days) and short-duration precipitation (of the order of 1 hour) are significant in the triggering of shallow landslides, since the critical short-duration rainfall intensity reduces as the antecedent accumulated rainfall increases. Experiences in Norway indicate that the maxi-mum intensity of rain within a short period of time (1-3 hours) during a storm is most critical for triggering of debris flows. Therefore empirical methods developed for prediction of initiation of debris flows include both long-duration and short-duration rain-fall. More recent research has focused on the spatial distribution of unstable areas and on better spatial resolution of the occurrence of landslide-triggering precipitation events. Spatial distribution can be assessed by analyzing the stability conditions for shallow landslides if reasonable estimates of strength parameters are available. In general, two different approaches may be adopted for the assessment of threshold values for rainfall-induced landslides: empirical methods that are based on past observations and statistical analyses, and numerical analyses that are based on geo-mechanical modelling. The former approach together with very short-term weather forecasting (now-casting) are commonly used in the design of early warning systems for debris flows.

Layered Metal Nanoparticle Structures on Electrodes for Sensing, Switchable Controlled Uptake/Release, and Photo-electrochemical Applications.

PubMed

Tel-Vered, Ran; Kahn, Jason S; Willner, Itamar

2016-01-06

Layered metal nanoparticle (NP) assemblies provide highly porous and conductive composites of unique electrical and optical (plasmonic) properties. Two methods to construct layered metal NP matrices are described, and these include the layer-by-layer deposition of NPs, or the electropolymerization of monolayer-functionalized NPs, specifically thioaniline-modified metal NPs. The layered NP composites are used as sensing matrices through the use of electrochemistry or surface plasmon resonance (SPR) as transduction signals. The crosslinking of the metal NP composites with molecular receptors, or the imprinting of molecular recognition sites into the electropolymerized NP matrices lead to selective and chiroselective sensing interfaces. Furthermore, the electrosynthesis of redox-active, imprinted, bis-aniline bridged Au NP composites yields electrochemically triggered "sponges" for the switchable uptake and release of electron-acceptor substrates, and results in conductive surfaces of electrochemically controlled wettability. Also, photosensitizer-relay-crosslinked Au NP composites, or electrochemically polymerized layered semiconductor quantum dot/metal NP matrices on electrodes, are demonstrated as functional nanostructures for photoelectrochemical applications. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Chassis integrated control for active suspension, active front steering and direct yaw moment systems using hierarchical strategy

NASA Astrophysics Data System (ADS)

Zhao, Jing; Wong, Pak Kin; Ma, Xinbo; Xie, Zhengchao

2017-01-01

This paper proposes a novel integrated controller with three-layer hierarchical structure to coordinate the interactions among active suspension system (ASS), active front steering (AFS) and direct yaw moment control (DYC). First of all, a 14-degree-of-freedom nonlinear vehicle dynamic model is constructed. Then, an upper layer is designed to calculate the total corrected moment for ASS and intermediate layer based on linear moment distribution. By considering the working regions of the AFS and DYC, the intermediate layer is functionalised to determine the trigger signal for the lower layer with corresponding weights. The lower layer is utilised to separately trace the desired value of each local controller and achieve the local control objectives of each subsystem. Simulation results show that the proposed three-layer hierarchical structure is effective in handling the working region of the AFS and DYC, while the quasi-experimental result shows that the proposed integrated controller is able to improve the lateral and vertical dynamics of the vehicle effectively as compared with a conventional electronic stability controller.

Gamma-telescopes Fermi/LAT and GAMMA-400 Trigger Systems Event Recognizing Methods Comparison

NASA Astrophysics Data System (ADS)

Arkhangelskaja, I. V.; Murchenko, A. E.; Chasovikov, E. N.; Arkhangelskiy, A. I.; Kheymits, M. D.

Usually instruments for high-energy γ-quanta registration consists of converter (where γ-quanta produced pairs) and calorimeter for particles energy measurements surrounded by anticoincidence shield used to events identification (whether incident particle was charged or neutral). The influence of pair formation by γ-quanta in shield and the backsplash (moved in the opposite direction particles created due high energy γ-rays interact with calorimeter) should be taken into account. It leads to decrease both effective area and registration efficiency at E>10 GeV. In the presented article the event recognizing methods used in Fermi/LAT trigger system is considered in comparison with the ones applied in counting and triggers signals formation system of gamma-telescope GAMMA-400. The GAMMA-400 (Gamma Astronomical Multifunctional Modular Apparatus) will be the new high-apogee space γ-observatory. The GAMMA-400 consist of converter-tracker based on silicon-strip coordinate detectors interleaved with tungsten foils, imaging calorimeter make of 2 layers of double (x, y) silicon strip coordinate detectors interleaved with planes of CsI(Tl) crystals and the electromagnetic calorimeter CC2 consists only of CsI(Tl) crystals. Several plastics detections systems used as anticoincidence shield, for particles energy and moving direction estimations. The main differences of GAMMA-400 constructions from Fermi/LAT one are using the time-of-flight system with base of 50 cm and double layer structure of plastic detectors provides more effective particles direction definition and backsplash rejection. Also two calorimeters in GAMMA-400 composed the total absorbtion spectrometer with total thickness ∼ 25 X0 or ∼1.2 λ0 for vertical incident particles registration and 54 X0 or 2.5 λ0 for laterally incident ones (where λ0 is nuclear interaction length). It provides energy resolution 1-2% for 10 GeV-3.0×103 GeV events while the Fermi/LAT energy resolution does not reach such a value because of its calorimeter thickness is only ∼10 X0 and energy of registered particles is defined by shower profile analysis. Less than 3% photons will be wrongly recognized as electrons or protons in double-layer ACtop taking into account both temporal and amplitude trigger marker analysis methods during onboard processing in the counting and triggers signals formation system of GAMMA-400. The proton rejection factor will be ∼10-5. The Fermi/LAT based on a 4 × 4 array of identical towers each contains a tracker, calorimeter and data acquisition module. Each tracker consists of 18 x-y silicon-strip layers. The calorimeter in each tower made of eight layers in a hodoscopic arrangement for measure the three-dimensional profiles of showers permits corrections for energy leakage and enhances the capability to discriminate hadronic cosmic rays. The each layer consists of 12 CsI(Tl) based bars. The segmented anticoincidence shield covers the array of towers. Unfortunately, several types of biases lead to systematic effects caused high values of relative systematic uncertainties of the exposure, the number of signal events, the induced fractional signal and so on. For example non confirmed announcement of ∼133 GeV line detection and lost sources in different Fermi catalogues (1FGL, 2FGL, 3FGL) - just well seen in 2FGL Cygnus X-3 (J2032.1+4049) does not appear in 3FGL. It allows to conclude sufficient biases in LAT characteristics obtained methods and event recognized algorithms. Now Fermi/LAT operates during ∼ 7 years but effective caveats methods continuously to be proposed. Respectively, continuation of measurements with use of other telescopes is necessary, and realization of GAMMA-400 will allow improving the results.

Anti-Fas Antibody Conjugated Nanoparticles Enhancing the Antitumor Effect of Camptothecin by Activating the Fas-FasL Apoptotic Pathway.

PubMed

Yu, Hongliang; He, Jian; Lu, Qian; Huo, Da; Yuan, Shanmei; Zhou, Zhengyang; Xu, Peipei; Hu, Yong

2016-11-09

Emerging evidence suggest that the introduction of Fas ligand (FasL) can enhance the Fas-dependent apoptosis and induce durable immune responses against tumor. However, selective triggering of apoptosis in tumor cells while sparing normal cells remains a great challenge for the application of FasL-based therapeutic strategies. Herein, smart nanoparticles (NPs) with a sandwich structure were fabricated. These NPs consist of a matrix metalloproteinase (MMP) cleavable PEG outer layer, an anti-Fas antibody middle layer, and a camptothecin (CPT)-loaded inner core. They could accumulate at a tumor site by the enhanced permeability and retention (EPR) effect. The removable PEG layer protects the cytotoxic anti-Fas antibody from premature contact with normal tissues, thus avoiding the unexpected lethal side effect before they reach the tumor site. Due to the high level of MMP expressed by tumor cells inside the tumor tissue, these NPs would shed their PEG layers, resulting in the exposure of anti-Fas antibody to bind the Fas receptor and triggering the apoptosis of tumor cells. Results of Western blot confirmed that these NPs could mimic the function of activated cytotoxic lymphocyte (CTL) to activate the Fas-FasL apoptosis pathway of tumor cells. With the aid of CPT payload, these anti-Fas antibody conjugated NPs achieved a high tumor inhibition in the B16 allograft tumor animal model. The design of these NPs provides a method for delivering cytotoxic ligand to targeting tissue, which may be valuable in cancer therapy.

Annular arc accelerator shock tube

NASA Technical Reports Server (NTRS)

Leibowitz, L. P. (Inventor)

1976-01-01

An annular arc accelerator shock tube employs a cold gas driver to flow a stream of gas from an expansion section through a high voltage electrode section to a test section, thus driving a shock wave in front of it. A glow discharge detects the shock wave and actuates a trigger generator which in turn fires spark-gap switches to discharge a bank of capacitors across a centered cathode and an annular anode in tandem electrode sections. The initial shock wave passes through the anode section from the cathode section thereby depositing energy into the flow gas without the necessity of any diaphragm opening in the gas flow from the expansion section through the electrode sections.

Access to CAMAC from VxWorks and UNIX in DART

DOE Office of Scientific and Technical Information (OSTI.GOV)

Streets, J.; Meadows, J.; Moore, C.

1996-02-01

All High Energy Physics experiments at Fermilab include CAMAC modules which need to be read out for each triggered event. There is also a need to access CAMAC modules for control and monitoring of the experiment. As part of the DART Project the authors have developed a package of software for CAMAC access from UNIX and VxWorks platforms, with support for several hardware interfaces. The authors report on developments for the CES CBD8210 VME to parallel CAMAC, the Hytec VSD2992 VME to serial CAMAC and Jorway 411S SCSI to parallel and serial CAMAC branch drivers, and give a summary ofmore » the timings obtained.« less

Multiple "Curriculum" Meanings Heighten Debate over Standards

ERIC Educational Resources Information Center

Gewertz, Catherine

2011-01-01

Calls for shared curricula for the common standards have triggered renewed debates about who decides what students learn, and even about varied meanings of the word "curriculum," adding layers of complexity to the job of translating the broad learning goals into classroom teaching. The most recent calls for common curricula came from the American…

Near-infrared light-triggered "on/off" motion of polymer multilayer rockets.

PubMed

Wu, Zhiguang; Lin, Xiankun; Wu, Yingjie; Si, Tieyan; Sun, Jianmin; He, Qiang

2014-06-24

We describe an approach to modulating the on-demand motion of catalytic polymer-based microengines via near-infrared (NIR) laser irradiation. The polymer multilayer motor was fabricated by the template-assisted layer-by-layer assembly and subsequently deposition of platinum nanoparticles inside and a thin gold shell outside. Then a mixed monolayer of a tumor-targeted peptide and an antifouling poly(ethylene glycol) was functionalized on the gold shell. The microengines remain motionless at the critical peroxide concentration (0.1%, v/v); however, NIR illumination on the engines leads to a photothermal effect and thus rapidly triggers the motion of the catalytic engines. Computational modeling explains the photothermal effect and gives the temperature profile accordingly. Also, the photothermal effect can alone activate the motion of the engines in the absence of the peroxide fuel, implying that it may eliminate the use of toxic fuel in the future. The targeted recognition ability and subsequently killing of cancer cells by the photothermal effect under the higher power of a NIR laser were illustrated. Our results pave the way to apply self-propelled synthetic engines in biomedical fields.

Electrodeposition to construct free-standing chitosan/layered double hydroxides hydro-membrane for electrically triggered protein release.

PubMed

Zhao, Pengkun; Zhao, Yanan; Xiao, Ling; Deng, Hongbing; Du, Yumin; Chen, Yun; Shi, Xiaowen

2017-10-01

In this study, we report the electrodeposition of a chitosan/layered double hydroxides (LDHs) hydro-membrane for protein release triggered by an electrical signal. The electrodeposition was performed in a chitosan and insulin loaded LDHs suspension in the absence of salt. A free-standing chitosan/LDHs hydro-membrane was generated on the electrode with improved mechanical properties, which is dramatically different from the weak hydrogel deposited in the presence of salt. The amount of LDHs in the hydro-membrane affects the optical transmittance and multilayered structure of the hybrid membrane. Compared to the weak chitosan/LDHs hydrogel, the hydro-membrane has a higher insulin loading capacity and the release of insulin is relatively slow. By biasing electrical potentials to the hydro-membrane, the release behavior of insulin can be adjusted accordingly. In addition, the chitosan/LDHs hydro-membrane showed no toxicity to cells. Our results provide a facile method to construct a chitosan/LDHs hybrid multilayered hydro-membrane and suggest the great potential of the hydro-membrane in controlled protein release. Copyright © 2017 Elsevier B.V. All rights reserved.

3-Dimensional Root Cause Diagnosis via Co-analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zheng, Ziming; Lan, Zhiling; Yu, Li

2012-01-01

With the growth of system size and complexity, reliability has become a major concern for large-scale systems. Upon the occurrence of failure, system administrators typically trace the events in Reliability, Availability, and Serviceability (RAS) logs for root cause diagnosis. However, RAS log only contains limited diagnosis information. Moreover, the manual processing is time-consuming, error-prone, and not scalable. To address the problem, in this paper we present an automated root cause diagnosis mechanism for large-scale HPC systems. Our mechanism examines multiple logs to provide a 3-D fine-grained root cause analysis. Here, 3-D means that our analysis will pinpoint the failure layer,more » the time, and the location of the event that causes the problem. We evaluate our mechanism by means of real logs collected from a production IBM Blue Gene/P system at Oak Ridge National Laboratory. It successfully identifies failure layer information for 219 failures during 23-month period. Furthermore, it effectively identifies the triggering events with time and location information, even when the triggering events occur hundreds of hours before the resulting failures.« less

Environmental drivers of Ixodes ricinus abundance in forest fragments of rural European landscapes.

PubMed

Ehrmann, Steffen; Liira, Jaan; Gärtner, Stefanie; Hansen, Karin; Brunet, Jörg; Cousins, Sara A O; Deconchat, Marc; Decocq, Guillaume; De Frenne, Pieter; De Smedt, Pallieter; Diekmann, Martin; Gallet-Moron, Emilie; Kolb, Annette; Lenoir, Jonathan; Lindgren, Jessica; Naaf, Tobias; Paal, Taavi; Valdés, Alicia; Verheyen, Kris; Wulf, Monika; Scherer-Lorenzen, Michael

2017-09-06

The castor bean tick (Ixodes ricinus) transmits infectious diseases such as Lyme borreliosis, which constitutes an important ecosystem disservice. Despite many local studies, a comprehensive understanding of the key drivers of tick abundance at the continental scale is still lacking. We analyze a large set of environmental factors as potential drivers of I. ricinus abundance. Our multi-scale study was carried out in deciduous forest fragments dispersed within two contrasting rural landscapes of eight regions, along a macroclimatic gradient stretching from southern France to central Sweden and Estonia. We surveyed the abundance of I. ricinus, plant community composition, forest structure and soil properties and compiled data on landscape structure, macroclimate and habitat properties. We used linear mixed models to analyze patterns and derived the relative importance of the significant drivers. Many drivers had, on their own, either a moderate or small explanatory value for the abundance of I. ricinus, but combined they explained a substantial part of variation. This emphasizes the complex ecology of I. ricinus and the relevance of environmental factors for tick abundance. Macroclimate only explained a small fraction of variation, while properties of macro- and microhabitat, which buffer macroclimate, had a considerable impact on tick abundance. The amount of forest and the composition of the surrounding rural landscape were additionally important drivers of tick abundance. Functional (dispersules) and structural (density of tree and shrub layers) properties of the habitat patch played an important role. Various diversity metrics had only a small relative importance. Ontogenetic tick stages showed pronounced differences in their response. The abundance of nymphs and adults is explained by the preceding stage with a positive relationship, indicating a cumulative effect of drivers. Our findings suggest that the ecosystem disservices of tick-borne diseases, via the abundance of ticks, strongly depends on habitat properties and thus on how humans manage ecosystems from the scale of the microhabitat to the landscape. This study stresses the need to further evaluate the interaction between climate change and ecosystem management on I. ricinus abundance.

Computational DNA hole spectroscopy: A new tool to predict mutation hotspots, critical base pairs, and disease 'driver' mutations.

PubMed

Villagrán, Martha Y Suárez; Miller, John H

2015-08-27

We report on a new technique, computational DNA hole spectroscopy, which creates spectra of electron hole probabilities vs. nucleotide position. A hole is a site of positive charge created when an electron is removed. Peaks in the hole spectrum depict sites where holes tend to localize and potentially trigger a base pair mismatch during replication. Our studies of mitochondrial DNA reveal a correlation between L-strand hole spectrum peaks and spikes in the human mutation spectrum. Importantly, we also find that hole peak positions that do not coincide with large variant frequencies often coincide with disease-implicated mutations and/or (for coding DNA) encoded conserved amino acids. This enables combining hole spectra with variant data to identify critical base pairs and potential disease 'driver' mutations. Such integration of DNA hole and variance spectra could ultimately prove invaluable for pinpointing critical regions of the vast non-protein-coding genome. An observed asymmetry in correlations, between the spectrum of human mtDNA variations and the L- and H-strand hole spectra, is attributed to asymmetric DNA replication processes that occur for the leading and lagging strands.

Climate variability rather than overstocking causes recent large scale cover changes of Tibetan pastures.

PubMed

Lehnert, L W; Wesche, K; Trachte, K; Reudenbach, C; Bendix, J

2016-04-13

The Tibetan Plateau (TP) is a globally important "water tower" that provides water for nearly 40% of the world's population. This supply function is claimed to be threatened by pasture degradation on the TP and the associated loss of water regulation functions. However, neither potential large scale degradation changes nor their drivers are known. Here, we analyse trends in a high-resolution dataset of grassland cover to determine the interactions among vegetation dynamics, climate change and human impacts on the TP. The results reveal that vegetation changes have regionally different triggers: While the vegetation cover has increased since the year 2000 in the north-eastern part of the TP due to an increase in precipitation, it has declined in the central and western parts of the TP due to rising air temperature and declining precipitation. Increasing livestock numbers as a result of land use changes exacerbated the negative trends but were not their exclusive driver. Thus, we conclude that climate variability instead of overgrazing has been the primary cause for large scale vegetation cover changes on the TP since the new millennium. Since areas of positive and negative changes are almost equal in extent, pasture degradation is not generally proceeding.

Environmental Drivers of West Nile Fever Epidemiology in Europe and Western Asia—A Review

PubMed Central

Paz, Shlomit; Semenza, Jan C.

2013-01-01

Abiotic and biotic conditions are both important determinants of West Nile Fever (WNF) epidemiology. Ambient temperature plays an important role in the growth rates of vector populations, the interval between blood meals, viral replication rates and transmission of West Nile Virus (WNV). The contribution of precipitation is more complex and less well understood. In this paper we discuss impacts of climatic parameters (temperature, relative humidity, precipitation) and other environmental drivers (such as bird migration, land use) on WNV transmission in Europe. WNV recently became established in southeastern Europe, with a large outbreak in the summer of 2010 and recurrent outbreaks in 2011 and 2012. Abundant competent mosquito vectors, bridge vectors, infected (viremic) migrating and local (amplifying) birds are all important characteristics of WNV transmission. In addition, certain key climatic factors, such as increased ambient temperatures, and by extension climate change, may also favor WNF transmission, and they should be taken into account when evaluating the risk of disease spread in the coming years. Monitoring epidemic precursors of WNF, such as significant temperature deviations in high risk areas, could be used to trigger vector control programs and public education campaigns. PMID:23939389

Metronome LKM: An open source virtual keyboard driver to measure experiment software latencies.

PubMed

Garaizar, Pablo; Vadillo, Miguel A

2017-10-01

Experiment software is often used to measure reaction times gathered with keyboards or other input devices. In previous studies, the accuracy and precision of time stamps has been assessed through several means: (a) generating accurate square wave signals from an external device connected to the parallel port of the computer running the experiment software, (b) triggering the typematic repeat feature of some keyboards to get an evenly separated series of keypress events, or (c) using a solenoid handled by a microcontroller to press the input device (keyboard, mouse button, touch screen) that will be used in the experimental setup. Despite the advantages of these approaches in some contexts, none of them can isolate the measurement error caused by the experiment software itself. Metronome LKM provides a virtual keyboard to assess an experiment's software. Using this open source driver, researchers can generate keypress events using high-resolution timers and compare the time stamps collected by the experiment software with those gathered by Metronome LKM (with nanosecond resolution). Our software is highly configurable (in terms of keys pressed, intervals, SysRq activation) and runs on 2.6-4.8 Linux kernels.

Different regional climatic drivers of Holocene large wildfires in boreal forests of northeastern America

NASA Astrophysics Data System (ADS)

Remy, Cécile C.; Hély, Christelle; Blarquez, Olivier; Magnan, Gabriel; Bergeron, Yves; Lavoie, Martin; Ali, Adam A.

2017-03-01

Global warming could increase climatic instability and large wildfire activity in circumboreal regions, potentially impairing both ecosystem functioning and human health. However, links between large wildfire events and climatic and/or meteorological conditions are still poorly understood, partly because few studies have covered a wide range of past climate-fire interactions. We compared palaeofire and simulated climatic data over the last 7000 years to assess causes of large wildfire events in three coniferous boreal forest regions in north-eastern Canada. These regions span an east-west cline, from a hilly region influenced by the Atlantic Ocean currently dominated by Picea mariana and Abies balsamea to a flatter continental region dominated by Picea mariana and Pinus banksiana. The largest wildfires occurred across the entire study zone between 3000 and 1000 cal. BP. In western and central continental regions these events were triggered by increases in both the fire-season length and summer/spring temperatures, while in the eastern region close to the ocean they were likely responses to hydrological (precipitation/evapotranspiration) variability. The impact of climatic drivers on fire size varied spatially across the study zone, confirming that regional climate dynamics could modulate effects of global climate change on wildfire regimes.

Wireless acquisition of multi-channel seismic data using the Seismobile system

NASA Astrophysics Data System (ADS)

Isakow, Zbigniew

2017-11-01

This paper describes the wireless acquisition of multi-channel seismic data using a specialized mobile system, Seismobile, designed for subsoil diagnostics for transportation routes. The paper presents examples of multi-channel seismic records obtained during system tests in a configuration with 96 channels (4 landstreamers of 24-channel) and various seismic sources. Seismic waves were generated at the same point using different sources: a 5-kg hammer, a Gisco's source with a 90-kg pile-driver, and two other the pile-drivers of 45 and 70 kg. Particular attention is paid to the synchronization of source timing, the measurement of geometry by autonomous GPS systems, and the repeatability of triggering measurements constrained by an accelerometer identifying the seismic waveform. The tests were designed to the registration, reliability, and range of the wireless transmission of survey signals. The effectiveness of the automatic numbering of measuring modules was tested as the system components were arranged and fixed to the streamers. After measurements were completed, the accuracy and speed of data downloading from the internal memory (SDHC 32GB WiFi) was determined. Additionally, the functionality of automatic battery recharging, the maximum survey duration, and the reliability of battery discharge signalling were assessed.

Shifted energy fluxes, increased Bowen ratios, and reduced thaw depths linked with drainage-induced changes in permafrost ecosystem structure

NASA Astrophysics Data System (ADS)

Göckede, Mathias; Kittler, Fanny; Kwon, Min Jung; Burjack, Ina; Heimann, Martin; Kolle, Olaf; Zimov, Nikita; Zimov, Sergey

2017-12-01

Hydrologic conditions are a key factor in Arctic ecosystems, with strong influences on ecosystem structure and related effects on biogeophysical and biogeochemical processes. With systematic changes in water availability expected for large parts of the northern high-latitude region in the coming centuries, knowledge on shifts in ecosystem functionality triggered by altered water levels is crucial for reducing uncertainties in climate change predictions. Here, we present findings from paired ecosystem observations in northeast Siberia comprising a drained and a control site. At the drainage site, the water table has been artificially lowered by up to 30 cm in summer for more than a decade. This sustained primary disturbance in hydrologic conditions has triggered a suite of secondary shifts in ecosystem properties, including vegetation community structure, snow cover dynamics, and radiation budget, all of which influence the net effects of drainage. Reduced thermal conductivity in dry organic soils was identified as the dominating drainage effect on energy budget and soil thermal regime. Through this effect, reduced heat transfer into deeper soil layers leads to shallower thaw depths, initially leading to a stabilization of organic permafrost soils, while the long-term effects on permafrost temperature trends still need to be assessed. At the same time, more energy is transferred back into the atmosphere as sensible heat in the drained area, which may trigger a warming of the lower atmospheric surface layer.

Triggered instabilities in rocket motors and active combustion control for an incinerator afterburner

NASA Astrophysics Data System (ADS)

Wicker, Josef M.

1999-11-01

Two branches of research are conducted in this thesis. The first deals with nonlinear combustion response as a mechanism for triggering combustion instabilities in solid rocket motors. A nonlinear wave equation is developed to study a wide class of combustion response functions to second-order in fluctuation amplitude. Conditions for triggering are derived from analysis of limit cycles, and regions of triggering are found in parametric space. Introduction of linear cross-coupling and quadratic self-coupling among the acoustic modes appears to be how the nonlinear combustion response produces triggering to a stable limit cycle. Regions of initial conditions corresponding to stable pulses were found, suggesting that stability depends on initial phase angle and harmonic content, as well as the composite amplitude, of the pulse. Also, dependence of nonlinear stability upon system parameters is considered. The second part of this thesis presents research for a controller to improve the emissions of an incinerator afterburner. The developed controller was experimentally tested at the Naval Air Warfare Center (NAWC), on a 50kW-scale model of an afterburner for Naval shipboard incinerator applications. Acoustic forcing of the combustor's reacting shear layer is used to control the formation of coherent vortical structures, within which favorable fuel-air mixing and efficient combustion can occur. Laser-based measurements of CO emissions are used as the performance indicator for the combustor. The controller algorithm is based on the downhill simplex method and adjusts the shear layer forcing parameters in order to minimize the CO emissions. The downhill simplex method was analyzed with respect to its behavior in the face of time-variation of the plant and noise in the sensor signal, and was modified to account for these difficulties. The control system has experimentally demonstrated the ability (1) to find optimal control action for single- and multi-variable control, (2) to maintain optimal control for time-varying operating states, and (3) to automatically adjust auxiliary fuel in response to changing stoichiometry of the incoming waste pyrolysis gas. Also presented but not tested in the experiments are an expert-type model-guidance feature to aid convergence of the controller to optimum control, and methodology for maintaining flammability.

Onset of a Declining Trend in Fatal Motor Vehicle Crashes Involving Drunk-driving in Japan

PubMed Central

Nakahara, Shinji; Katanoda, Kota; Ichikawa, Masao

2013-01-01

Background In Japan, introduction of severe drunk-driving penalties and a lower blood alcohol concentration (BAC) limit in June 2002 was followed by a substantial reduction in fatal alcohol-related crashes. However, previous research suggests that this reduction started before the legal amendments. The causes of the decrease have not been studied in detail. Methods Monthly police data on fatal road traffic crashes from January 1995 to August 2006 were analyzed using a joinpoint regression model to identify change-points in the trends of the proportion of drunk-driving among drivers primarily responsible for fatal crashes. We analyzed the data by BAC level (≥0.5 or <0.5 mg/ml), then conducted analyses stratified by vehicle type (car or motorcycle) and age group (<45 or ≥45 years) only for the proportion of those with a BAC of 0.5 mg/ml or higher. Results Among all drivers, the proportion of those with a BAC of 0.5 mg/ml or higher and those with a BAC greater than 0 but less than 0.5 mg/ml showed a change-point from increase to decrease in February 2000 and in May 2002, respectively. The proportion of those with a BAC of 0.5 mg/ml or higher showed a change-point from increase to decrease in October 1999 among car drivers and in April 2000 among drivers younger than 45 years. There was no change-point among motorcyclists. A change-point from no trend to a decrease in January 2002 was observed among those 45 years or older. Conclusions The change-point identified around the end of 1999 to the start of 2000 suggests that a high-profile fatal crash in November 1999, which drew media attention and provoked public debate, triggered subsequent changes in drunk-driving behavior. PMID:23604061

How to Assess Vulnerabilities of Water Policies to Global Change?

NASA Astrophysics Data System (ADS)

Kumar, A.; Haasnoot, M.; Weijs, S.

2017-12-01

Water managers are confronted with uncertainties arising from hydrological, societal, economical and political drivers. To manage these uncertainties two paradigms have been identified: top-down and bottom-up approaches. Top-down or prediction-based approaches use socio-economic scenarios together with a discrete set of GCM projections (often downscaled) to assess the expected impact of drivers and policies on water resource system through various hydrological and social systems models. Adaptation strategies to alleviate these impacts are then identified and tested against the scenarios. To address GCM and downscaling uncertainties, these approaches put more focus on climate predictions, rather than the decision problem itself. Triggered by the wish to have a more scenario-neutral approach and address downscaling uncertainties, recent analyses have been shifted towards vulnerability-based (bottom-up or decision-centric) approaches. They begin at the local scale by addressing socio-economic responses to climate, often involving stakeholder's input; identify vulnerabilities under a larger sample of plausible futures and evaluate sensitivity and robustness of possible adaptation options. Several bottom-up approaches have emerged so far and are increasingly recommended. Fundamentally they share several core ideas, however, subtle differences exist in vulnerability assessment, visualization tools for exploring vulnerabilities and computational methods used for identifying robust water policies. Through this study, we try to identify how these approaches are progressing, how the climate and non-climate uncertainties are being confronted and how to integrate existing and new tools. We find that choice of a method may depend on the number of vulnerability drivers identified and type of threshold levels (environmental conditions or policy objectives) defined. Certain approaches are suited well for assessing adaptive capacities, tipping points and sequencing of decisions. However, visualization of the vulnerability domain is still challenging if multiple drivers are present. New emerging tools are focused on generating synthetic scenarios, addressing multiple objectives, linking decision-making frameworks to adaptation pathways and communicating risks to the stakeholders.

Heathlands confronting global change: drivers of biodiversity loss from past to future scenarios

PubMed Central

Fagúndez, Jaime

2013-01-01

Background Heathlands are dynamic plant communities characterized by a high cover of sclerophyllous, ericoid shrubs that develop over nutrient-poor soils. Interest in the preservation of these habitats in Europe has increased over the last decades, but over this time there has been a general decline in habitat quality, affecting community structure, ecosystem functions and biodiversity. Negative drivers that trigger these changes include land-use changes (i.e. habitat destruction and fragmentation), pollution, climate change, natural succession and human management, as well as the presence of invasive exotic species. Scope Based on recent scientific literature, the effect of each of these potential drivers on a wide set of factors, including physiological traits, species richness and diversity, community structure, ecosystem functions and soil conditions, is reviewed. The effects of these drivers are generally understood, but the direction and magnitude of factor interactions, whenever studied, have shown high variability. Conclusions Habitat loss and fragmentation affect sensitive species and ecosystem functions. The nature of the surrounding area will condition the quality of the heathland remnants by, for example, propagule pressure from invasive species. The dominant ericoid shrubs can be out-competed by vigorous perennial grasses with increased atmospheric nitrogen deposition, although interactions with climate and management practices may either counteract or enhance this process. Grazing or periodic burning promotes heath loss but site-specific combined treatments maintain species diversity and community structure. Climate change alone moderately affects plant diversity, community structure and ecosystem functions. Combined with other factors, climatic changes will condition heath development, mainly with regard to key aspects such as seed set and seedling establishment, rare species occurrence and nutrient cycling in the soil. It is essential to address the effects of not only individual factors, but their interactions, together with land-use history, on heathland development and conservation in order to predict habitat response to future scenarios. PMID:23223202

Heathlands confronting global change: drivers of biodiversity loss from past to future scenarios.

PubMed

Fagúndez, Jaime

2013-02-01

Heathlands are dynamic plant communities characterized by a high cover of sclerophyllous, ericoid shrubs that develop over nutrient-poor soils. Interest in the preservation of these habitats in Europe has increased over the last decades, but over this time there has been a general decline in habitat quality, affecting community structure, ecosystem functions and biodiversity. Negative drivers that trigger these changes include land-use changes (i.e. habitat destruction and fragmentation), pollution, climate change, natural succession and human management, as well as the presence of invasive exotic species. Based on recent scientific literature, the effect of each of these potential drivers on a wide set of factors, including physiological traits, species richness and diversity, community structure, ecosystem functions and soil conditions, is reviewed. The effects of these drivers are generally understood, but the direction and magnitude of factor interactions, whenever studied, have shown high variability. Habitat loss and fragmentation affect sensitive species and ecosystem functions. The nature of the surrounding area will condition the quality of the heathland remnants by, for example, propagule pressure from invasive species. The dominant ericoid shrubs can be out-competed by vigorous perennial grasses with increased atmospheric nitrogen deposition, although interactions with climate and management practices may either counteract or enhance this process. Grazing or periodic burning promotes heath loss but site-specific combined treatments maintain species diversity and community structure. Climate change alone moderately affects plant diversity, community structure and ecosystem functions. Combined with other factors, climatic changes will condition heath development, mainly with regard to key aspects such as seed set and seedling establishment, rare species occurrence and nutrient cycling in the soil. It is essential to address the effects of not only individual factors, but their interactions, together with land-use history, on heathland development and conservation in order to predict habitat response to future scenarios.

Sloshing of a bubbly magma reservoir as a mechanism of triggered eruptions

NASA Astrophysics Data System (ADS)

Namiki, Atsuko; Rivalta, Eleonora; Woith, Heiko; Walter, Thomas R.

2016-06-01

Large earthquakes sometimes activate volcanoes both in the near field as well as in the far field. One possible explanation is that shaking may increase the mobility of the volcanic gases stored in magma reservoirs and conduits. Here experimentally and theoretically we investigate how sloshing, the oscillatory motion of fluids contained in a shaking tank, may affect the presence and stability of bubbles and foams, with important implications for magma conduits and reservoirs. We adopt this concept from engineering: severe earthquakes are known to induce sloshing and damage petroleum tanks. Sloshing occurs in a partially filled tank or a fully filled tank with density-stratified fluids. These conditions are met at open summit conduits or at sealed magma reservoirs where a bubbly magma layer overlays a newly injected denser magma layer. We conducted sloshing experiments by shaking a rectangular tank partially filled with liquids, bubbly fluids (foams) and fully filled with density-stratified fluids; i.e., a foam layer overlying a liquid layer. In experiments with foams, we find that foam collapse occurs for oscillations near the resonance frequency of the fluid layer. Low viscosity and large bubble size favor foam collapse during sloshing. In the layered case, the collapsed foam mixes with the underlying liquid layer. Based on scaling considerations, we constrain the conditions for the occurrence of foam collapse in natural magma reservoirs. We find that seismic waves with lower frequencies < 1 Hz, usually excited by large earthquakes, can resonate with magma reservoirs whose width is > 0.5 m. Strong ground motion > 0.1 m s- 1 can excite sloshing with sufficient amplitude to collapse a magma foam in an open conduit or a foam overlying basaltic magma in a closed magma reservoir. The gas released from the collapsed foam may infiltrate the rock or diffuse through pores, enhancing heat transfer, or may generate a gas slug to cause a magmatic eruption. The overturn in the magma reservoir provides new nucleation sites which may help to prepare a following/delayed eruption. Mt. Fuji erupted 49 days after the large Hoei earthquake (1707) both dacitic and basaltic magmas. The eruption might have been triggered by magma mixing through sloshing.

Fire induced reproductive mechanisms of a Symphoricarpos (Caprifoliaceae) shrub after dormant season burning.

PubMed

Scasta, John Derek; Engle, David M; Harr, Ryan N; Debinski, Diane M

2014-12-01

Symphoricarpos, a genus of the Caprifoliaceae family, consists of about 15 species of clonal deciduous shrubs in North America and 1 species endemic to China. In North American tallgrass prairie, Symphoricarpos orbiculatus (buckbrush) is the dominant shrub often forming large colonies via sexual and asexual reproductive mechanisms. Symphoricarpos shrubs, in particular S. orbiculatus, use a unique sexual reproductive mechanism known as layering where vertical stems droop and the tips root upon contact with the soil. Because of conflicting societal values of S. orbiculatus for conservation and agriculture and the current attempt to restore historical fire regimes, there is a need for basic research on the biological response of S. orbiculatus to anthropogenic burning regimes. From 2007 through 2013 we applied prescribed fires in the late dormant season on grazed pastures in the Grand River Grasslands of Iowa. From 2011 to 2013, we measured how S. orbiculatus basal resprouting and layering stems were affected by patchy fires on grazed pastures, complete pasture fires on grazed pastures or fire exclusion without grazing for more than three years. We measured ramet height, ramet canopy diameter, stems per ramet, ramets per 100 m 2 , and probability of new layering stems 120 days after fire. Height in burned plots was lower than unburned plots but S. orbiculatus reached ~ 84% of pre-burn height 120 days after fire. Stems per ramet were 2x greater in the most recently burned plots due to basal re-sprouting. Canopy diameter and density of ramets was not affected by time since fire, but burned pastures had marginally lower densities than plots excluded from fire (P = 0.07). Fire triggered new layering stems and no new layering stems were found in plots excluded from fire. The mechanisms of both basal sprouting and aerial layering after fire suggest S. orbiculatus is tolerant to dormant season fires. Furthermore, dormant season fires, regardless if they were patchy fires or complete pasture fires, did not result in mortality of S. orbiculatus. Dormant season fires can reduce S. orbiculatus structural dominance and maintain lower ramet densities but also trigger basal resprouting and layering.

Adaptive Water Sampling based on Unsupervised Clustering

NASA Astrophysics Data System (ADS)

Py, F.; Ryan, J.; Rajan, K.; Sherman, A.; Bird, L.; Fox, M.; Long, D.

2007-12-01

Autonomous Underwater Vehicles (AUVs) are widely used for oceanographic surveys, during which data is collected from a number of on-board sensors. Engineers and scientists at MBARI have extended this approach by developing a water sampler specialy for the AUV, which can sample a specific patch of water at a specific time. The sampler, named the Gulper, captures 2 liters of seawater in less than 2 seconds on a 21" MBARI Odyssey AUV. Each sample chamber of the Gulper is filled with seawater through a one-way valve, which protrudes through the fairing of the AUV. This new kind of device raises a new problem: when to trigger the gulper autonomously? For example, scientists interested in studying the mobilization and transport of shelf sediments would like to detect intermediate nepheloïd layers (INLs). To be able to detect this phenomenon we need to extract a model based on AUV sensors that can detect this feature in-situ. The formation of such a model is not obvious as identification of this feature is generally based on data from multiple sensors. We have developed an unsupervised data clustering technique to extract the different features which will then be used for on-board classification and triggering of the Gulper. We use a three phase approach: 1) use data from past missions to learn the different classes of data from sensor inputs. The clustering algorithm will then extract the set of features that can be distinguished within this large data set. 2) Scientists on shore then identify these features and point out which correspond to those of interest (e.g. nepheloïd layer, upwelling material etc) 3) Embed the corresponding classifier into the AUV control system to indicate the most probable feature of the water depending on sensory input. The triggering algorithm looks to this result and triggers the Gulper if the classifier indicates that we are within the feature of interest with a predetermined threshold of confidence. We have deployed this method of online classification and sampling based on AUV depth and HOBI Labs Hydroscat-2 sensor data. Using approximately 20,000 data samples the clustering algorithm generated 14 clusters with one identified as corresponding to a nepheloïd layer. We demonstrate that such a technique can be used to reliably and efficiently sample water based on multiple sources of data in real-time.

The muon pretrigger system of the HERA-B experiment

NASA Astrophysics Data System (ADS)

Bocker, M.; Adams, M.; Bechtle, P.; Buchholz, P.; Cruse, C.; Husemann, U.; Klaus, E.; Koch, N.; Kolander, M.; Kolotaev, I.; Riege, H.; Schutt, J.; Schwenninger, B.; van Staa, R.; Wegener, D.

2001-08-01

One of the main goals of the HERA-B experiment at DESY in Hamburg, Germany, is to study the properties of B-mesons with the emphasis on CP violation. B-mesons are produced in hadronic interactions of a 920-GeV proton beam with an internal wire target. An effective bunch crossing rate of about 8.5 MHz leads to about 200 charged tracks per event. Therefore, a highly selective and efficient trigger system providing high suppression of background events is required. The HERA-B trigger system consists of four levels. A rate reduction factor of 200 is aimed at by the first-level trigger (FLT). The muon pretrigger system, as a part of the FLT, is a modular system consisting of about 100 large-size VME modules of three different types: the pretrigger link board (PLB), the pretrigger coincidence unit (PCU), and the pretrigger message generator (PMG). The data rate processed by the pretrigger system is about 19.5 GByte/s. The PLBs process digitized hit information in eight independent electronic channels in parallel. Every electronic channel handles 32 bits of hit information received from the front-end driver buffer system. Optical links operating at 800 Mb/s transmit the data after serialization to PCUs, which calculate coincidences using complex programmable logic devices. The PMGs transform this coincidence information into messages for the FLT processors. The concept and design as well as results of the muon pretrigger running at HERA-B are presented.

Reference Data Layers for Earth and Environmental Science: History, Frameworks, Science Needs, Approaches, and New Technologies

NASA Astrophysics Data System (ADS)

Lenhardt, W. C.

2015-12-01

Global Mapping Project, Web-enabled Landsat Data (WELD), International Satellite Land Surface Climatology Project (ISLSCP), hydrology, solid earth dynamics, sedimentary geology, climate modeling, integrated assessments and so on all have needs for or have worked to develop consistently integrated data layers for Earth and environmental science. This paper will present an overview of an abstract notion of data layers of this types, what we are referring to as reference data layers for Earth and environmental science, highlight some historical examples, and delve into new approaches. The concept of reference data layers in this context combines data availability, cyberinfrastructure and data science, as well as domain science drivers. We argue that current advances in cyberinfrastructure such as iPython notebooks and integrated science processing environments such as iPlant's Discovery Environment coupled with vast arrays of new data sources warrant another look at the how to create, maintain, and provide reference data layers. The goal is to provide a context for understanding science needs for reference data layers to conduct their research. In addition, to the topics described above this presentation will also outline some of the challenges to and present some ideas for new approaches to addressing these needs. Promoting the idea of reference data layers is relevant to a number of existing related activities such as EarthCube, RDA, ESIP, the nascent NSF Regional Big Data Innovation Hubs and others.

Should drivers be operating within an automation-free bandwidth? Evaluating haptic steering support systems with different levels of authority.

PubMed

Petermeijer, Sebastiaan M; Abbink, David A; de Winter, Joost C F

2015-02-01

The aim of this study was to compare continuous versus bandwidth haptic steering guidance in terms of lane-keeping behavior, aftereffects, and satisfaction. An important human factors question is whether operators should be supported continuously or only when tolerance limits are exceeded. We aimed to clarify this issue for haptic steering guidance by investigating costs and benefits of both approaches in a driving simulator. Thirty-two participants drove five trials, each with a different level of haptic support: no guidance (Manual); guidance outside a 0.5-m bandwidth (Band1); a hysteresis version of Band1, which guided back to the lane center once triggered (Band2); continuous guidance (Cont); and Cont with double feedback gain (ContS). Participants performed a reaction time task while driving. Toward the end of each trial, the guidance was unexpectedly disabled to investigate aftereffects. All four guidance systems prevented large lateral errors (>0.7 m). Cont and especially ContS yielded smaller lateral errors and higher time to line crossing than Manual, Band1, and Band2. Cont and ContS yielded short-lasting aftereffects, whereas Band1 and Band2 did not. Cont yielded higher self-reported satisfaction and faster reaction times than Band1. Continuous and bandwidth guidance both prevent large driver errors. Continuous guidance yields improved performance and satisfaction over bandwidth guidance at the cost of aftereffects and variability in driver torque (indicating human-automation conflicts). The presented results are useful for designers of haptic guidance systems and support critical thinking about the costs and benefits of automation support systems.

Simulations of Atmospheric Neutral Wave Coupling to the Ionosphere

NASA Astrophysics Data System (ADS)

Siefring, C. L.; Bernhardt, P. A.

2005-12-01

The densities in the E- and F-layer plasmas are much less than the density of background neutral atmosphere. Atmospheric neutral waves are primary sources of plasma density fluctuations and are the sources for triggering plasma instabilities. The neutral atmosphere supports acoustic waves, acoustic gravity waves, and Kelvin Helmholtz waves from wind shears. These waves help determine the structure of the ionosphere by changes in neutral density that affect ion-electron recombination and by neutral velocities that couple to the plasma via ion-neutral collisions. Neutral acoustic disturbances can arise from thunderstorms, chemical factory explosions and intentional high-explosive tests. Based on conservation of energy, acoustic waves grow in amplitude as they propagate upwards to lower atmospheric densities. Shock waves can form in an acoustic pulse that is eventually damped by viscosity. Ionospheric effects from acoustic waves include transient perturbations of E- and F-Regions and triggering of E-Region instabilities. Acoustic-gravity waves affect the ionosphere over large distances. Gravity wave sources include thunderstorms, auroral region disturbances, Space Shuttle launches and possibly solar eclipses. Low frequency acoustic-gravity waves propagate to yield traveling ionospheric disturbances (TID's), triggering of Equatorial bubbles, and possible periodic structuring of the E-Region. Gravity wave triggering of equatorial bubbles is studied numerically by solving the equations for plasma continuity and ion velocity along with Ohms law to provide an equation for the induced electric potential. Slow moving gravity waves provide density depressions on bottom of ionosphere and a gravitational Rayleigh-Taylor instability is initiated. Radar scatter detects field aligned irregularities in the resulting plasma bubble. Neutral Kelvin-Helmholtz waves are produced by strong mesospheric wind shears that are also coincident with the formation of intense E-layers. An atmospheric model for periodic structures with Kelvin-Helmholtz (KH) wavelengths is used to show the development of quasi-periodic structures in the E-layer. For the model, a background atmosphere near 100 km altitude with a scale height of 12.2 km is subjected to a wind shear profile varying by 100 m/s over a distance of 1.7 km. This neutral speed shear drives the KH instability with a growth time of about 100 seconds. The neutral KH wave is a source of plasma turbulence. The E-layer responds to the KH-Wave structure in the neutral atmosphere as an electrodynamic tracer. The plasma flow leads to small scale plasma field aligned irregularities from a gradient drift, plasma interchange instability (GDI) or a Farley-Buneman, two-stream instability (FBI). These irregularities are detected by radar scatter as quasi-periodic structures. All of these plasma phenomena would not occur without the initiation by neutral atmospheric waves.

GaAs photoconductive semiconductor switch

DOEpatents

Loubriel, G.M.; Baca, A.G.; Zutavern, F.J.

1998-09-08

A high gain, optically triggered, photoconductive semiconductor switch (PCSS) implemented in GaAs as a reverse-biased pin structure with a passivation layer above the intrinsic GaAs substrate in the gap between the two electrodes of the device is disclosed. The reverse-biased configuration in combination with the addition of the passivation layer greatly reduces surface current leakage that has been a problem for prior PCSS devices and enables employment of the much less expensive and more reliable DC charging systems instead of the pulsed charging systems that needed to be used with prior PCSS devices. 5 figs.

A stable lithium-rich surface structure for lithium-rich layered cathode materials

PubMed Central

Kim, Sangryun; Cho, Woosuk; Zhang, Xiaobin; Oshima, Yoshifumi; Choi, Jang Wook

2016-01-01

Lithium ion batteries are encountering ever-growing demand for further increases in energy density. Li-rich layered oxides are considered a feasible solution to meet this demand because their specific capacities often surpass 200 mAh g−1 due to the additional lithium occupation in the transition metal layers. However, this lithium arrangement, in turn, triggers cation mixing with the transition metals, causing phase transitions during cycling and loss of reversible capacity. Here we report a Li-rich layered surface bearing a consistent framework with the host, in which nickel is regularly arranged between the transition metal layers. This surface structure mitigates unwanted phase transitions, improving the cycling stability. This surface modification enables a reversible capacity of 218.3 mAh g−1 at 1C (250 mA g−1) with improved cycle retention (94.1% after 100 cycles). The present surface design can be applied to various battery electrodes that suffer from structural degradations propagating from the surface. PMID:27886178

Influences and interactions of inundation, peat, and snow on active layer thickness

DOE PAGES

Atchley, Adam L.; Coon, Ethan T.; Painter, Scott L.; ...

2016-05-18

Active layer thickness (ALT), the uppermost layer of soil that thaws on an annual basis, is a direct control on the amount of organic carbon potentially available for decomposition and release to the atmosphere as carbon-rich Arctic permafrost soils thaw in a warming climate. Here, we investigate how key site characteristics affect ALT using an integrated surface/subsurface permafrost thermal hydrology model. ALT is most sensitive to organic layer thickness followed by snow depth but is relatively insensitive to the amount of water on the landscape with other conditions held fixed. Furthermore, the weak ALT sensitivity to subsurface saturation suggests thatmore » changes in Arctic landscape hydrology may only have a minor effect on future ALT. But, surface inundation amplifies the sensitivities to the other parameters and under large snowpacks can trigger the formation of near-surface taliks.« less

Development of a new scintillation-trigger detector for the MTV experiment using aluminum-metallized film tape

NASA Astrophysics Data System (ADS)

Sakamoto, Yuko; Ozaki, Sachi; Tanaka, Saki; Tanuma, Ryosuke; Yoshida, Tatsuru; Murata, Jiro

2014-09-01

A new type of trigger-scintillation counter array designed for the MTV experiment at TRIUMF-ISAC has been developed, using aluminum-metallized film tape for wrapping. The MTV experiment aims to perform the finest precision test of time reversal symmetry in nuclear beta decay. In that purpose, we search non-zero T-Violating transverse polarization of electrons emitted from polarized Li-8 nuclei. It uses a cylindrical drift chamber (CDC) as the main electron-tracking detector. The trigger-scintillation counter consists of 12-segmented 1 mm thick 300 mm long thin plastic scintillation counters. This counter is placed inside the CDC to generate a trigger signal. The required assembling precision of +-0.5 mm was a tricky point when we tried to use conventional total reflection mode. Indeed, produce an air-layer surrounding the scintillating bar to keep good light transmission was the main issue. For this reason, we tried to use a new wrapping material made of metallized-aluminum tape, which has a good mirror-like reflecting surface on both sides of the tape. Through this report, we will compare detection efficiency and light attenuation between conventional and new wrapping materials.

Effect of n = 3 perturbation field amplitudes below the ELM triggering threshold on edge and SOL transport in NSTX

DOE PAGES

J. M. Canik; Lore, J. D.; Ahn, J. -W.; ...

2013-01-12

Here, the pulsed application of n = 3 magnetic perturbation fields with amplitudes below that which triggers ELMs results in distinct, transient responses observable on several edge and divertor diagnostics in NSTX. We refer to these responses as Sub-Threshold Edge Perturbations (STEPs). An analysis of edge measurements suggests that STEPs result in increased transport in the plasma edge and scrape-off layer, which leads to augmentation of the intrinsic strike point splitting due to error fields, i.e., an intensification of the helical divertor footprint flux pattern. These effects are much smaller in magnitude than those of triggered ELMs, and are observedmore » for the duration of the field perturbation measured internal to the vacuum vessel. In addition, STEPs are correlated with changes to the MHD activity, along with transient reductions in the neutron production rate. Ideally the STEPs could be used to provide density control and prevent impurity accumulation, in the same manner that on-demand ELM triggering is used on NSTX, without the impulsive divertor fluxes and potential for damage to plasma facing components associated with ELMs.« less

14 CFR Appendix G to Part 417 - Natural and Triggered Lightning Flight Commit Criteria

Code of Federal Regulations, 2010 CFR

2010-01-01

... time. A cumulus cloud formed locally and a cirrus layer that is physically separated from that cumulus... launch point at the same time. Bright band means an enhancement of radar reflectivity caused by frozen.... Cloud means a visible mass of water droplets or ice crystals produced by condensation of water vapor in...

14 CFR Appendix G to Part 417 - Natural and Triggered Lightning Flight Commit Criteria

Code of Federal Regulations, 2011 CFR

2011-01-01

... time. A cumulus cloud formed locally and a cirrus layer that is physically separated from that cumulus... launch point at the same time. Bright band means an enhancement of radar reflectivity caused by frozen.... Cloud means a visible mass of water droplets or ice crystals produced by condensation of water vapor in...

Adaptive management of large aquatic ecosystem recovery programs in the United States.

PubMed

Thom, Ronald; St Clair, Tom; Burns, Rebecca; Anderson, Michael

2016-12-01

Adaptive management (AM) is being employed in a number of programs in the United States to guide actions to restore aquatic ecosystems because these programs are both expensive and are faced with significant uncertainties. Many of these uncertainties are associated with prioritizing when, where, and what kind of actions are needed to meet the objectives of enhancing ecosystem services and recovering threatened and endangered species. We interviewed nine large-scale aquatic ecosystem restoration programs across the United States to document the lessons learned from implementing AM. In addition, we recorded information on ecological drivers (e.g., endangered fish species) for the program, and inferred how these drivers reflected more generic ecosystem services. Ecosystem services (e.g., genetic diversity, cultural heritage), albeit not explicit drivers, were either important to the recovery or enhancement of the drivers, or were additional benefits associated with actions to recover or enhance the program drivers. Implementing programs using AM lessons learned has apparently helped achieve better results regarding enhancing ecosystem services and restoring target species populations. The interviews yielded several recommendations. The science and AM program must be integrated into how the overall restoration program operates in order to gain understanding and support, and effectively inform management decision-making. Governance and decision-making varied based on its particular circumstances. Open communication within and among agency and stakeholder groups and extensive vetting lead up to decisions. It was important to have an internal agency staff member to implement the AM plan, and a clear designation of roles and responsibilities, and long-term commitment of other involved parties. The most important management questions and information needs must be identified up front. It was imperative to clearly identify, link and continually reinforce the essential components of an AM plan, including objectives, constraints, uncertainties, hypotheses, management actions, decision criteria and triggers, monitoring, and research. Some employed predictive models and the results of research on uncertainties to vet options for actions. Many relied on best available science and professional judgment to decide if adjustments to actions were needed. All programs emphasized the need to be nimble enough to be responsive to new information and make necessary adjustments to management action implementation. We recommend that ecosystem services be explicit drivers of restoration programs to facilitate needed funding and communicate to the general public and with the global efforts on restoring and conserving ecosystems. Copyright © 2016 Elsevier Ltd. All rights reserved.

Indocyanine Green-Loaded Liposomes for Light-Triggered Drug Release.

PubMed

Lajunen, Tatu; Kontturi, Leena-Stiina; Viitala, Lauri; Manna, Moutusi; Cramariuc, Oana; Róg, Tomasz; Bunker, Alex; Laaksonen, Timo; Viitala, Tapani; Murtomäki, Lasse; Urtti, Arto

2016-06-06

Light-triggered drug delivery systems enable site-specific and time-controlled drug release. In previous work, we have achieved this with liposomes containing gold nanoparticles in the aqueous core. Gold nanoparticles absorb near-infrared light and release the energy as heat that increases the permeability of the liposomal bilayer, thus releasing the contents of the liposome. In this work, we replaced the gold nanoparticles with the clinically approved imaging agent indocyanine green (ICG). The ICG liposomes were stable at storage conditions (4-22 °C) and at body temperature, and fast near-infrared (IR) light-triggered drug release was achieved with optimized phospholipid composition and a 1:50 ICG-to-lipid molar ratio. Encapsulated small molecular calcein and FITC-dextran (up to 20 kDa) were completely released from the liposomes after light exposure for 15 s. Location of ICG in the PEG layer of the liposomes was simulated with molecular dynamics. ICG has important benefits as a light-triggering agent in liposomes: fast content release, improved stability, improved possibility of liposomal size control, regulatory approval to use in humans, and the possibility of imaging the in vivo location of the liposomes based on the fluorescence of ICG. Near-infrared light used as a triggering mechanism has good tissue penetration and safety. Thus, ICG liposomes are an attractive option for light-controlled and efficient delivery of small and large drug molecules.

Natural wind variability triggered drop in German redispatch volume and costs from 2015 to 2016.

PubMed

Wohland, Jan; Reyers, Mark; Märker, Carolin; Witthaut, Dirk

2018-01-01

Avoiding dangerous climate change necessitates the decarbonization of electricity systems within the next few decades. In Germany, this decarbonization is based on an increased exploitation of variable renewable electricity sources such as wind and solar power. While system security has remained constantly high, the integration of renewables causes additional costs. In 2015, the costs of grid management saw an all time high of about € 1 billion. Despite the addition of renewable capacity, these costs dropped substantially in 2016. We thus investigate the effect of natural climate variability on grid management costs in this study. We show that the decline is triggered by natural wind variability focusing on redispatch as a main cost driver. In particular, we find that 2016 was a weak year in terms of wind generation averages and the occurrence of westerly circulation weather types. Moreover, we show that a simple model based on the wind generation time series is skillful in detecting redispatch events on timescales of weeks and beyond. As a consequence, alterations in annual redispatch costs in the order of hundreds of millions of euros need to be understood and communicated as a normal feature of the current system due to natural wind variability.

ATL response to arsenic/interferon therapy is triggered by SUMO/PML/RNF4-dependent Tax degradation.

PubMed

Dassouki, Zeina; Sahin, Umut; El Hajj, Hiba; Jollivet, Florence; Kfoury, Youmna; Lallemand-Breitenbach, Valérie; Hermine, Olivier; de Thé, Hugues; Bazarbachi, Ali

2015-01-15

The human T-cell lymphotropic virus type I (HTLV-1) Tax transactivator initiates transformation in adult T-cell leukemia/lymphoma (ATL), a highly aggressive chemotherapy-resistant malignancy. The arsenic/interferon combination, which triggers degradation of the Tax oncoprotein, selectively induces apoptosis of ATL cell lines and has significant clinical activity in Tax-driven murine ATL or human patients. However, the role of Tax loss in ATL response is disputed, and the molecular mechanisms driving degradation remain elusive. Here we demonstrate that ATL-derived or HTLV-1-transformed cells are dependent on continuous Tax expression, suggesting that Tax degradation underlies clinical responses to the arsenic/interferon combination. The latter enforces promyelocytic leukemia protein (PML) nuclear body (NB) formation and partner protein recruitment. In arsenic/interferon-treated HTLV-1 transformed or ATL cells, Tax is recruited onto NBs and undergoes PML-dependent hyper-sumoylation by small ubiquitin-like modifier (SUMO)2/3 but not SUMO1, ubiquitination by RNF4, and proteasome-dependent degradation. Thus, the arsenic/interferon combination clears ATL through degradation of its Tax driver, and this regimen could have broader therapeutic value by promoting degradation of other pathogenic sumoylated proteins. © 2015 by The American Society of Hematology.

Seasonal patterns of seismicity and deformation at the Alutu geothermal reservoir, Ethiopia, induced by hydrological loading

NASA Astrophysics Data System (ADS)

Birhanu, Yelebe; Wilks, Matthew; Biggs, Juliet; Kendall, J.-Michael; Ayele, Atalay; Lewi, Elias

2018-05-01

Seasonal variations in the seismicity of volcanic and geothermal reservoirs are usually attributed to the hydrological cycle. Here, we focus on the Aluto-Langano geothermal system, Ethiopia, where the climate is monsoonal and there is abundant shallow seismicity. We deployed temporary networks of seismometers and GPS receivers to understand the drivers of unrest. First, we show that a statistically significant peak in seismicity occurred 2-3 months after the main rainy season, with a second, smaller peak of variable timing. Seasonal seismicity is commonly attributed to variations in either surface loading or reservoir pore pressure. As loading will cause subsidence and overpressure will cause uplift, comparing seismicity rates with continuous GPS, enables us to distinguish between mechanisms. At Aluto, the major peak in seismicity is coincident with the high stand of nearby lakes and maximum subsidence, indicating that it is driven by surface loading. The magnitude of loading is insufficient to trigger widespread crustal seismicity but the geothermal reservoir at Aluto is likely sensitive to small perturbations in the stress field. Thus we demonstrate that monsoonal loading can produce seismicity in geothermal reservoirs, and the likelihood of both triggered and induced seismicity varies seasonally.

Microprocessor-controlled, wide-range streak camera

DOE Office of Scientific and Technical Information (OSTI.GOV)

Amy E. Lewis, Craig Hollabaugh

Bechtel Nevada/NSTec recently announced deployment of their fifth generation streak camera. This camera incorporates many advanced features beyond those currently available for streak cameras. The arc-resistant driver includes a trigger lockout mechanism, actively monitors input trigger levels, and incorporates a high-voltage fault interrupter for user safety and tube protection. The camera is completely modular and may deflect over a variable full-sweep time of 15 nanoseconds to 500 microseconds. The camera design is compatible with both large- and small-format commercial tubes from several vendors. The embedded microprocessor offers Ethernet connectivity, and XML [extensible markup language]-based configuration management with non-volatile parameter storagemore » using flash-based storage media. The camera’s user interface is platform-independent (Microsoft Windows, Unix, Linux, Macintosh OSX) and is accessible using an AJAX [asynchronous Javascript and XML]-equipped modem browser, such as Internet Explorer 6, Firefox, or Safari. User interface operation requires no installation of client software or browser plug-in technology. Automation software can also access the camera configuration and control using HTTP [hypertext transfer protocol]. The software architecture supports multiple-simultaneous clients, multiple cameras, and multiple module access with a standard browser. The entire user interface can be customized.« less

Microprocessor-controlled wide-range streak camera

NASA Astrophysics Data System (ADS)

Lewis, Amy E.; Hollabaugh, Craig

2006-08-01

Bechtel Nevada/NSTec recently announced deployment of their fifth generation streak camera. This camera incorporates many advanced features beyond those currently available for streak cameras. The arc-resistant driver includes a trigger lockout mechanism, actively monitors input trigger levels, and incorporates a high-voltage fault interrupter for user safety and tube protection. The camera is completely modular and may deflect over a variable full-sweep time of 15 nanoseconds to 500 microseconds. The camera design is compatible with both large- and small-format commercial tubes from several vendors. The embedded microprocessor offers Ethernet connectivity, and XML [extensible markup language]-based configuration management with non-volatile parameter storage using flash-based storage media. The camera's user interface is platform-independent (Microsoft Windows, Unix, Linux, Macintosh OSX) and is accessible using an AJAX [asynchronous Javascript and XML]-equipped modem browser, such as Internet Explorer 6, Firefox, or Safari. User interface operation requires no installation of client software or browser plug-in technology. Automation software can also access the camera configuration and control using HTTP [hypertext transfer protocol]. The software architecture supports multiple-simultaneous clients, multiple cameras, and multiple module access with a standard browser. The entire user interface can be customized.

Alternative Lengthening of Telomeres Mediated by Mitotic DNA Synthesis Engages Break-Induced Replication Processes

PubMed Central

Min, Jaewon; Wright, Woodring E.

2017-01-01

ABSTRACT Alternative lengthening of telomeres (ALT) is a telomerase-independent telomere maintenance mechanism that occurs in a subset of cancers. By analyzing telomerase-positive cells and their human TERC knockout-derived ALT human cell lines, we show that ALT cells harbor more fragile telomeres representing telomere replication problems. ALT-associated replication defects trigger mitotic DNA synthesis (MiDAS) at telomeres in a RAD52-dependent, but RAD51-independent, manner. Telomeric MiDAS is a conservative DNA synthesis process, potentially mediated by break-induced replication, similar to type II ALT survivors in Saccharomyces cerevisiae. Replication stresses induced by ectopic oncogenic expression of cyclin E, G-quadruplexes, or R-loop formation facilitate the ALT pathway and lead to telomere clustering, a hallmark of ALT cancers. The TIMELESS/TIPIN complex suppresses telomere clustering and telomeric MiDAS, whereas the SMC5/6 complex promotes them. In summary, ALT cells exhibit more telomere replication defects that result in persistent DNA damage responses at telomeres, leading to the engagement of telomeric MiDAS (spontaneous mitotic telomere synthesis) that is triggered by DNA replication stress, a potential driver of genomic duplications in cancer. PMID:28760773

Host-induced bacterial cell wall decomposition mediates pattern-triggered immunity in Arabidopsis

PubMed Central

Liu, Xiaokun; Grabherr, Heini M; Willmann, Roland; Kolb, Dagmar; Brunner, Frédéric; Bertsche, Ute; Kühner, Daniel; Franz-Wachtel, Mirita; Amin, Bushra; Felix, Georg; Ongena, Marc; Nürnberger, Thorsten; Gust, Andrea A

2014-01-01

Peptidoglycans (PGNs) are immunogenic bacterial surface patterns that trigger immune activation in metazoans and plants. It is generally unknown how complex bacterial structures such as PGNs are perceived by plant pattern recognition receptors (PRRs) and whether host hydrolytic activities facilitate decomposition of bacterial matrices and generation of soluble PRR ligands. Here we show that Arabidopsis thaliana, upon bacterial infection or exposure to microbial patterns, produces a metazoan lysozyme-like hydrolase (lysozyme 1, LYS1). LYS1 activity releases soluble PGN fragments from insoluble bacterial cell walls and cleavage products are able to trigger responses typically associated with plant immunity. Importantly, LYS1 mutant genotypes exhibit super-susceptibility to bacterial infections similar to that observed on PGN receptor mutants. We propose that plants employ hydrolytic activities for the decomposition of complex bacterial structures, and that soluble pattern generation might aid PRR-mediated immune activation in cell layers adjacent to infection sites. DOI: http://dx.doi.org/10.7554/eLife.01990.001 PMID:24957336

Phase separation of metal-added corium and its effect on a steam explosion

NASA Astrophysics Data System (ADS)

Min, B. T.; Kim, J. H.; Hong, S. W.; Hong, S. H.; Park, I. K.; Song, J. H.; Kim, H. D.

2008-07-01

To simulate a relocation of molten core material and its interaction phenomenon with water during a severe accident in a nuclear reactor, a typical corium of UO 2/ZrO 2/Zr/Stainless steel mixed at a 62 wt%, 15 wt%, 12 wt% and 11 wt%, respectively, was melted and then cooled down to become a solidified ingot. It was shown that the molten corium was separated into two layers, of which the upper layer was oxide mixtures and the lower layer was metal alloys. The upper layer was UO 2 and ZrO 2 and the lower layer mostly consisted of metal mixtures such as uranium, zirconium and stainless steel. Iron content varied with the positions and about a half of it existed as an alloy such as Fe 2U. Uranium metal was produced by reduction of UO 2 by zirconium metal. The average densities of the upper oxide layer and the lower metal layer were 8.802 and 9.411 g/cm 3, respectively. In another test, metal-added molten corium was poured into water and it showed that a steam explosion could occur by applying an external trigger.

Sustained ophthalmic delivery of highly soluble drug using pH-triggered inner layer-embedded contact lens.

PubMed

Zhu, Qiang; Cheng, Hongbo; Huo, Yingnan; Mao, Shirui

2018-06-10

In the present work the feasibility of using inner layer-embedded contact lenses (CLs) to achieve sustained release of highly water soluble drug, betaxolol hydrochloride (BH) on the ocular surface was investigated. Blend film of cellulose acetate and Eudragit S100 was selected as the inner layer, while silicone hydrogel was used as outer layer to construct inner layer-embedded contact lenses. Influence of polymer ratio in the blend film on in vitro drug release behavior in phosphate buffered solution or simulated tear fluid was studied and drug-polymer interaction, erosion and swelling of the blend film were characterized to better understand drug-release mechanism. Storage stability of the inner layer-embedded contact lenses in phosphate buffer solution was also conducted, with ignorable drug loss and negligible change in drug release pattern within 30 days. In vivo pharmacokinetic study in rabbits showed sustained drug release for over 240 h in tear fluid, indicating prolonged drug precorneal residence time. In conclusion, cellulose acetate/Eudragit S100 inner layer-embedded contact lenses are quite promising as controlled-release carrier of highly water soluble drug for ophthalmic delivery. Copyright © 2018 Elsevier B.V. All rights reserved.

Cloud-Resolving Model Simulations of Aerosol-Cloud Interactions Triggered by Strong Aerosol Emissions in the Arctic

NASA Astrophysics Data System (ADS)

Wang, H.; Kravitz, B.; Rasch, P. J.; Morrison, H.; Solomon, A.

2014-12-01

Previous process-oriented modeling studies have highlighted the dependence of effectiveness of cloud brightening by aerosols on cloud regimes in warm marine boundary layer. Cloud microphysical processes in clouds that contain ice, and hence the mechanisms that drive aerosol-cloud interactions, are more complicated than in warm clouds. Interactions between ice particles and liquid drops add additional levels of complexity to aerosol effects. A cloud-resolving model is used to study aerosol-cloud interactions in the Arctic triggered by strong aerosol emissions, through either geoengineering injection or concentrated sources such as shipping and fires. An updated cloud microphysical scheme with prognostic aerosol and cloud particle numbers is employed. Model simulations are performed in pure super-cooled liquid and mixed-phase clouds, separately, with or without an injection of aerosols into either a clean or a more polluted Arctic boundary layer. Vertical mixing and cloud scavenging of particles injected from the surface is still quite efficient in the less turbulent cold environment. Overall, the injection of aerosols into the Arctic boundary layer can delay the collapse of the boundary layer and increase low-cloud albedo. The pure liquid clouds are more susceptible to the increase in aerosol number concentration than the mixed-phase clouds. Rain production processes are more effectively suppressed by aerosol injection, whereas ice precipitation (snow) is affected less; thus the effectiveness of brightening mixed-phase clouds is lower than for liquid-only clouds. Aerosol injection into a clean boundary layer results in a greater cloud albedo increase than injection into a polluted one, consistent with current knowledge about aerosol-cloud interactions. Unlike previous studies investigating warm clouds, the impact of dynamical feedback due to precipitation changes is small. According to these results, which are dependent upon the representation of ice nucleation processes in the employed microphysical scheme, Arctic geoengineering/shipping could have substantial local radiative effects, but is unlikely to be effective as the sole means of counterbalancing warming due to climate change.

Superposition of polarized waves at layered media: theoretical modeling and measurement

NASA Astrophysics Data System (ADS)

Finkele, Rolf; Wanielik, Gerd

1997-12-01

The detection of ice layers on road surfaces is a crucial requirement for a system that is designed to warn vehicle drivers of hazardous road conditions. In the millimeter wave regime at 76 GHz the dielectric constant of ice and conventional road surface materials (i.e. asphalt, concrete) is found to be nearly similar. Thus, if the layer of ice is very thin and thus is of the same shape of roughness as the underlying road surface it cannot be securely detected using conventional algorithmic approaches. The method introduced in this paper extents and applies the theoretical work of Pancharatnam on the superposition of polarized waves. The projection of the Stokes vectors onto the Poincare sphere traces a circle due to the variation of the thickness of the ice layer. The paper presents a method that utilizes the concept of wave superposition to detect this trace even if it is corrupted by stochastic variation due to rough surface scattering. Measurement results taken under real traffic conditions prove the validity of the proposed algorithms. Classification results are presented and the results discussed.

Anomalies of the upper water column in the Mediterranean Sea

NASA Astrophysics Data System (ADS)

Rivetti, Irene; Boero, Ferdinando; Fraschetti, Simonetta; Zambianchi, Enrico; Lionello, Piero

2017-04-01

The evolution of the upper water column in the Mediterranean Sea during more than 60 years is reconstructed in terms of few parameters describing the mixed layer and the seasonal thermocline. The analysis covers the period 1945-2011 using data from three public sources: MEDAR-MEDATLAS, World Ocean Database, MFS-VOS program. Five procedures for estimating the mixed layer depth are described, discussed and compared using the 20-year long time series of temperature profiles of the DYFAMED station in the Ligurian Sea. On this basis the so-called three segments profile model (which approximates the upper water column with three segments representing mixed layer, thermocline and deep layer) has been selected for a systematic analysis at Mediterranean scale. A widespread increase of the thickness and temperature of the mixed layer, increase of the depth and decrease of the temperature of the thermocline base have been observed in summer and autumn during the recent decades. It is shown that positive temperature extremes of the mixed layer and of its thickness are potential drivers of the mass mortalities of benthic invertebrates documented since 1983. Hotspots of mixed layer anomalies have been also identified. These results refine previous analyses showing that ongoing and future warming of upper Mediterranean is likely to increase mass mortalities by producing environmental conditions beyond the limit of tolerance of some benthic species.

The three-dimensional evolution of a plane mixing layer. Part 2: Pairing and transition to turbulence

NASA Technical Reports Server (NTRS)

Moser, Robert D.; Rogers, Michael M.

1992-01-01

The evolution of three-dimensional temporally evolving plane mixing layers through as many as three pairings was simulated numerically. Initial conditions for all simulations consisted of a few low-wavenumber disturbances, usually derived from linear stability theory, in addition to the mean velocity. Three-dimensional perturbations were used with amplitudes ranging from infinitesimal to large enough to trigger a rapid transition to turbulence. Pairing is found both to inhibit the growth of infinitesimal three-dimensional disturbances and to trigger the transition to turbulence in highly three dimensional flows. The mechanisms responsible for the growth of three-dimensionality as well as the initial phases of the transition to turbulence are described. The transition to turbulence is accompanied by the formation of thin sheets of span wise vorticity, which undergo a secondary roll up. Transition also produces an increase in the degree of scalar mixing, in agreement with experimental observations of mixing transition. Simulations were also conducted to investigate changes in span wise length scale that may occur in response to the change in stream wise length scale during a pairing. The linear mechanism for this process was found to be very slow, requiring roughly three pairings to complete a doubling of the span wise scale. Stronger three-dimensionality can produce more rapid scale changes but is also likely to trigger transition to turbulence. No evidence was found for a change from an organized array of rib vortices at one span wise scale to a similar array at a larger span wise scale.

The Presence of Dense Material in the Deep Mantle: Implications for Plate Motion

NASA Astrophysics Data System (ADS)

Stein, C.; Hansen, U.

2017-12-01

The dense material in the deep mantle strongly interacts with the convective flow in the mantle. On the one hand, it has a restoring effect on rising plumes. On the other hand, the dense material is swept about by the flow forming dense piles. Consequently this affects the plate motion and, in particular, the onset time and the style of plate tectonics varies considerably for different model scenarios. In this study we apply a thermochemical mantle convection model combined with a rheological model (temperature- and stress-dependent viscosity) that allows for plate formation according to the convective flow. The model's starting condition is the post-magma ocean period. We analyse a large number of model scenarios ranging from variations in thickness, density and depth of a layer of dense material to different initial temperatures.Furthermore, we present a mechanism in which the dense layer at the core-mantle boundary forms without prescribing the thickness or the density contrast. Due to advection-assisted diffusion, long-lived piles can be established that act on the style of convection and therefore on plate motion. We distinguish between the subduction-triggered regime with early plate tectonics and the plume-triggered regime with a late onset of plate tectonics. The formation of piles by advection-assisted diffusion is a typical phenomenon that appears not only at the lower boundary, but also at internal boundaries that form in the layering phase during the evolution of the system.

Exogenous Hydrogen Peroxide Contributes to Heme Oxygenase-1 Delaying Programmed Cell Death in Isolated Aleurone Layers of Rice Subjected to Drought Stress in a cGMP-Dependent Manner

PubMed Central

Wang, Guanghui; Xiao, Yu; Deng, Xiaojiang; Zhang, Heting; Li, Tingge; Chen, Huiping

2018-01-01

Hydrogen peroxide (H2O2) is a reactive oxygen species (ROS) that plays a dual role in plant cells. Here, we discovered that drought (20% polyethylene glycol-6000, PEG)-triggered decreases of HO-1 transcript expression and HO activity. However, exogenous H2O2 contributed toward the increase in HO-1 gene expression and activity of the enzyme under drought stress. Meanwhile, the HO-1 inducer hematin could mimic the effects of the H2O2 scavengers ascorbic acid (AsA) and dimethylthiourea (DMTU) and the H2O2 synthesis inhibitor diphenyleneiodonium (DPI) for scavenging or diminishing drought-induced endogenous H2O2. Conversely, the zinc protoporphyrin IX (ZnPPIX), an HO-1-specific inhibitor, reversed the effects of hematin. We further analyzed the endogenous H2O2 levels and HO-1 transcript expression levels of aleurone layers treated with AsA, DMTU, and DPI in the presence of exogenous H2O2 under drought stress, respectively. The results showed that in aleurone layers subjected to drought stress, when the endogenous H2O2 level was inhibited, the effect of exogenous H2O2 on the induction of HO-1 was enhanced. Furthermore, exogenous H2O2-activated HO-1 effectively enhanced amylase activity. Application of 8-bromoguanosine 3′,5′-cyclic guanosine monophosphate (8-Br-cGMP) (the membrane permeable cGMP analog) promoted the effect of exogenous H2O2-delayed PCD of aleurone layers in response to drought stress. More importantly, HO-1 delayed the programmed cell death (PCD) of aleurone layers by cooperating with nitric oxide (NO), and the delayed effect of NO on PCD was achieved via mediation by cGMP under drought stress. In short, in rice aleurone layers, exogenous H2O2 (as a signaling molecule) triggered HO-1 and delayed PCD via cGMP which possibly induced amylase activity under drought stress. In contrast, as a toxic by-product of cellular metabolism, the drought-generated H2O2 promoted cell death. PMID:29449858

Exogenous Hydrogen Peroxide Contributes to Heme Oxygenase-1 Delaying Programmed Cell Death in Isolated Aleurone Layers of Rice Subjected to Drought Stress in a cGMP-Dependent Manner.

PubMed

Wang, Guanghui; Xiao, Yu; Deng, Xiaojiang; Zhang, Heting; Li, Tingge; Chen, Huiping

2018-01-01

Hydrogen peroxide (H 2 O 2 ) is a reactive oxygen species (ROS) that plays a dual role in plant cells. Here, we discovered that drought (20% polyethylene glycol-6000, PEG)-triggered decreases of HO-1 transcript expression and HO activity. However, exogenous H 2 O 2 contributed toward the increase in HO-1 gene expression and activity of the enzyme under drought stress. Meanwhile, the HO-1 inducer hematin could mimic the effects of the H 2 O 2 scavengers ascorbic acid (AsA) and dimethylthiourea (DMTU) and the H 2 O 2 synthesis inhibitor diphenyleneiodonium (DPI) for scavenging or diminishing drought-induced endogenous H 2 O 2 . Conversely, the zinc protoporphyrin IX (ZnPPIX), an HO-1-specific inhibitor, reversed the effects of hematin. We further analyzed the endogenous H 2 O 2 levels and HO-1 transcript expression levels of aleurone layers treated with AsA, DMTU, and DPI in the presence of exogenous H 2 O 2 under drought stress, respectively. The results showed that in aleurone layers subjected to drought stress, when the endogenous H 2 O 2 level was inhibited, the effect of exogenous H 2 O 2 on the induction of HO-1 was enhanced. Furthermore, exogenous H 2 O 2 -activated HO-1 effectively enhanced amylase activity. Application of 8-bromoguanosine 3',5'-cyclic guanosine monophosphate (8-Br-cGMP) (the membrane permeable cGMP analog) promoted the effect of exogenous H 2 O 2 -delayed PCD of aleurone layers in response to drought stress. More importantly, HO-1 delayed the programmed cell death (PCD) of aleurone layers by cooperating with nitric oxide (NO), and the delayed effect of NO on PCD was achieved via mediation by cGMP under drought stress. In short, in rice aleurone layers, exogenous H 2 O 2 (as a signaling molecule) triggered HO-1 and delayed PCD via cGMP which possibly induced amylase activity under drought stress. In contrast, as a toxic by-product of cellular metabolism, the drought-generated H 2 O 2 promoted cell death.

Improving water content estimation on landslide-prone hillslopes using structurally-constrained inversion of electrical resistivity data

NASA Astrophysics Data System (ADS)

Heinze, Thomas; Möhring, Simon; Budler, Jasmin; Weigand, Maximilian; Kemna, Andreas

2017-04-01

Rainfall-triggered landslides are a latent danger in almost any place of the world. Due to climate change heavy rainfalls might occur more often, increasing the risk of landslides. With pore pressure as mechanical trigger, knowledge of water content distribution in the ground is essential for hazard analysis during monitoring of potentially dangerous rainfall events. Geophysical methods like electrical resistivity tomography (ERT) can be utilized to determine the spatial distribution of water content using established soil physical relationships between bulk electrical resistivity and water content. However, often more dominant electrical contrasts due to lithological structures outplay these hydraulic signatures and blur the results in the inversion process. Additionally, the inversion of ERT data requires further constraints. In the standard Occam inversion method, a smoothness constraint is used, assuming that soil properties change softly in space. This applies in many scenarios, as for example during infiltration of water without a clear saturation front. Sharp lithological layers with strongly divergent hydrological parameters, as often found in landslide prone hillslopes, on the other hand, are typically badly resolved by standard ERT. We use a structurally constrained ERT inversion approach for improving water content estimation in landslide prone hills by including a-priori information about lithological layers. Here the standard smoothness constraint is reduced along layer boundaries identified using seismic data or other additional sources. This approach significantly improves water content estimations, because in landslide prone hills often a layer of rather high hydraulic conductivity is followed by a hydraulic barrier like clay-rich soil, causing higher pore pressures. One saturated layer and one almost drained layer typically result also in a sharp contrast in electrical resistivity, assuming that surface conductivity of the soil does not change in similar order. Using synthetic data, we study the influence of uncertainties in the a-priori information on the inverted resistivity and estimated water content distribution. Based on our simulation results, we provide best-practice recommendations for field applications and suggest important tests to obtain reliable, reproducible and trustworthy results. We finally apply our findings to field data, compare conventional and improved analysis results, and discuss limitations of the structurally-constrained inversion approach.

The Farley-Buneman Instability in the Solar Chromosphere

NASA Astrophysics Data System (ADS)

Madsen, Chad A.; Dimant, Yakov S.; Oppenheim, Meers M.; Fontenla, Juan M.

2012-10-01

Strong currents drive the Farley-Buneman Instability (FBI) in the E-region ionosphere creating turbulence and heating. The solar chromosphere is a similar weakly ionized region with strong local Pedersen currents, and the FBI may play a role in sustaining the thin layer of enhanced temperature observed there. The plasma of the solar chromosphere requires a new theory of the FBI accounting for the presence of multiple ion species, higher temperatures and collisions between ionized metals and neutral hydrogen. This paper discusses the assumptions underlying the derivation of the multi-species FBI dispersion relation. It presents the predicted critical electron drift velocity needed to trigger the instability. Finally, this work argues that observed chromospheric neutral flow speeds are sufficiently large to trigger the multi-species FBI.

Dynamic Triggering around Fangshan Pluton near Beijing,China

NASA Astrophysics Data System (ADS)

Wang, W.; Gong, X.; Peng, Z.; Chen, Q.; Wu, C.

2011-12-01

Fangshan Pluton lies at SW of Beijing City and is formed at about 133-128Ma. The Pluton is surrounded by the NNE-trending Taihang mountain in the west as an "C" shape, and is in conjunction with the Northern China Plain along the Baobashan fault in the east. This region currently does not have abundant background seismicity, but previous studies (Peng et al., 2010, Wu et al. 2011) have shown that at least 4 major earthquakes in East Asia have triggered clear seismic events in this region. To further understand the dynamic triggering mechanism and improve the station coverage, we deployed the first batch temporal seismic array with 5 stations from 12/2008 to 7/2010 and the second batch with 11 stations around this area since 12/2010. Our temporary deployment was fortunate to capture the triggered seismicity following the 2011 Mw9.0 Tohoku-Oki, Japan, earthquake sequence. In this study, we use seismic data recorded by the permanent stations in the Capital Circle seismic network and our temporary deployment to investigate triggered seismicity following the 2010 Mw8.8 Chile earthquake and the Tohoku-Oki earthquake sequence. As was done before, we identify triggered earthquakes as impulsive seismic arrivals with clear P- and S-waves in 5 Hz high-pass-filtered three-component velocity seismograms and recorded by at least 3 stations. Most triggered earthquakes coincide with the large-amplitude Rayleigh waves. For the Tohoku-Oki case, we identify one weak event during the P-wave of the mainshock, and delayed triggering following the large-amplitude surface waves. In addition, triggered earthquakes can be seen in the Mw7.3 foreshock and mainshock of Tohoku earthquake, but not in aftershocks with 2 Mw>7.5 earthquakes in the following two months. These events mainly occurred at southwestern and western boundary region of the Pluton and are shallower (<5km) than normal earthquakes, which is similar to previous studies. Considering the abundant solution cavities and syncline/anticline structures developed during the magma intrusion, we suggest that the triggered earthquakes could occur at the weak boundary regions with abundant underground water that permeate into deep layer through the cracked syncline tips or faults. Our next step is to locate the triggered and background seismicity more precisely, and determine the focal mechanisms of the triggered events for better understanding of the source faults and necessary conditions for dynamic triggering in this region.

Synaptogenesis in the rat cerebellum: effects of early hypo- and hyperthyroidism.

PubMed

Nicholson, J L; Altman, J

1972-05-05

The number of synapses in the molecular layer of the rat cerebellum is reduced by early hypo-and hyperthyroidism within 30 days. Hypothyroidism retards synaptogenesis after 10 days, while hyperthyroidism accelerates synaptogenesis initially, but by 21 days the number of synapses is reduced. The sensitivity of developing synapses to thyroid hormone may permit analysis of the events triggering synaptogenesis.

The response of Fraxinus nigra forest ground-layer vegetation to emulated emerald ash borer mortality and management strategies in northern Minnesota, USA

Treesearch

Christopher E. Looney; Anthony W. D' Amato; Brian J. Palik; Robert A. Slesak; Mitchell A. Slater

2017-01-01

When an invasive organism targets a dominant tree species, it can trigger unprecedented shifts in forest plant communities. Emerald ash borer (EAB; Agrilus planipennis Fairmaire), an invasive insect that kills by girdling trees, represents a significant threat to North American Fraxinus (ash) species. EAB has already decimated...

Effects of fire severity on plant nutrient uptake reinforce alternate pathways of succession in boreal forests

Treesearch

A. Shenoy; K. Kielland; J.F. Johnstone

2013-01-01

Fire activity in the North American boreal region is projected to increase under a warming climate and trigger changes in vegetation composition. In black spruce forests of interior Alaska, fire severity impacts residual organic layer depth which is strongly linked to the relative dominance of deciduous versus coniferous trees in early succession. These alternate...

Climate‐Dependent Heat‐Triggered Opening Mechanism of Banksia Seed Pods

PubMed Central

Schoeppler, Vanessa; Merritt, David J.; Best, Christine; Maire, Eric; Adrien, Jérôme; Spaeker, Oliver; Janssen, Nils; Gladisch, Johannes; Gierlinger, Notburga; Miller, Ben P.; Fratzl, Peter

2017-01-01

Abstract Heat‐triggered fruit opening and delayed release of mature seeds are widespread among plants in fire‐prone ecosystems. Here, the material characteristics of the seed‐containing follicles of Banksia attenuata (Proteaceae), which open in response to heat frequently caused by fire, are investigated. Material analysis reveals that long‐term dimensional stability and opening temperatures of follicles collected across an environmental gradient increase as habitats become drier, hotter, and more fire prone. A gradual increase in the biaxial curvature of the hygroscopic valves provides the follicles in the driest region with the highest flexural rigidity. The irreversible deformation of the valves for opening is enabled via a temperature‐dependent reduction of the elastic modulus of the innermost tissue layer, which then allows releasing the stresses previously generated by shrinkage of the fiber bundles in the adjacent layer during follicle drying. These findings illustrate the level of sophistication by which this species optimizes its fruit opening mechanism over a large distribution range with varying environmental conditions, and may not only have great relevance for developing biomimetic actuators, but also for elucidating the species' capacity to cope with climatic changes. PMID:29375977

Mast cells in atherosclerotic cardiovascular disease - Activators and actions.

PubMed

Kovanen, Petri T; Bot, Ilze

2017-12-05

Mast cells are potent actors involved in inflammatory reactions in various tissues, including both in the intimal and the adventitial layers of atherosclerotic arteries. In the arterial intima, the site of atherogenesis, mast cells are activated to degranulate, and thereby triggered to release an abundance of preformed inflammatory mediators, notably histamine, heparin, neutral proteases and cytokines stored in their cytoplasmic secretory granules. Depending on the stimulus, mast cell activation may also launch prolonged synthesis and secretion of single bioactive molecules, such as cytokines and derivatives of arachidonic acid. The mast cell-derived mediators may impede the functions of different types of cells present in atherosclerotic lesions, and also compromise the structural and functional integrity of the intimal extracellular matrix. In the adventitial layer of atherosclerotic coronary arteries, mast cells locate next to peptidergic sensory nerve fibers, which, by releasing neuropeptides may activate mast cells to release vasoactive compounds capable of triggering local vasoconstriction. The concerted actions of arterial mast cells have the potential to contribute to the initiation and progression of atherosclerosis, and ultimately to destabilization and rupture of an advanced atherosclerotic plaque with ensuing atherothrombotic complications. Copyright © 2017 Elsevier B.V. All rights reserved.

Responsive block copolymer photonics triggered by protein-polyelectrolyte coacervation.

PubMed

Fan, Yin; Tang, Shengchang; Thomas, Edwin L; Olsen, Bradley D

2014-11-25

Ionic interactions between proteins and polyelectrolytes are demonstrated as a method to trigger responsive transitions in block copolymer (BCP) photonic gels containing one neutral hydrophobic block and one cationic hydrophilic block. Poly(2-vinylpyridine) (P2VP) blocks in lamellar poly(styrene-b-2-vinylpyridine) block copolymer thin films are quaternized with primary bromides to yield swollen gels that show strong reflectivity peaks in the visible range; exposure to aqueous solutions of various proteins alters the swelling ratios of the quaternized P2VP (QP2VP) gel layers in the PS-QP2VP materials due to the ionic interactions between proteins and the polyelectrolyte. Parameters such as charge density, hydrophobicity, and cross-link density of the QP2VP gel layers as well as the charge and size of the proteins play significant roles on the photonic responses of the BCP gels. Differences in the size and pH-dependent charge of proteins provide a basis for fingerprinting proteins based on their temporal and equilibrium photonic response. The results demonstrate that the BCP gels and their photonic effect provide a robust and visually interpretable method to differentiate different proteins.

On the Resonant Behavior of a Weakly Compressible Water Layer During Tsunamigenic Earthquakes

NASA Astrophysics Data System (ADS)

Cecioni, Claudia; Bellotti, Giorgio

2018-01-01

Tsunamigenic earthquakes trigger pressure waves in the ocean, given the weak compressibility of the sea water. For particular conditions, a resonant behavior of the water layer can occur, which influences the energy transfer from the sea-bed motion to the ocean. In this paper, the resonance conditions are explained and analyzed, focusing on the hydro-acoustic waves in the proximity of the earthquake area. A preliminary estimation of the generation parameters (sea-bed rising time, velocity) is given, by means of parametric numerical simulations for simplified conditions. The results confirm the importance of measuring, modeling, and interpreting such waves for tsunami early detection and warning.

On the Resonant Behavior of a Weakly Compressible Water Layer During Tsunamigenic Earthquakes

NASA Astrophysics Data System (ADS)

Cecioni, Claudia; Bellotti, Giorgio

2018-04-01

Tsunamigenic earthquakes trigger pressure waves in the ocean, given the weak compressibility of the sea water. For particular conditions, a resonant behavior of the water layer can occur, which influences the energy transfer from the sea-bed motion to the ocean. In this paper, the resonance conditions are explained and analyzed, focusing on the hydro-acoustic waves in the proximity of the earthquake area. A preliminary estimation of the generation parameters (sea-bed rising time, velocity) is given, by means of parametric numerical simulations for simplified conditions. The results confirm the importance of measuring, modeling, and interpreting such waves for tsunami early detection and warning.

SiC/GaN Based Optically Triggered MESFET for High Power Efficiency and High Radiation Resistance Solid State Switch Application for Actuator System

DTIC Science & Technology

2016-06-23

somnath.chattopadhyay@csun.edu 1-818-677-7197 clean/etch. Excessively hard- baked photoresist can usually be dissolved in piranha etching solution. 48 hours of...coated onto the freshly cleaned and dried wafer at 3000RPM, then soft- baked at 180ºC for 120 seconds. This gives a PMGI layer of about 0.4µm. Then the...PR is spin coated onto the wafer at about 4000RPM and soft baked at 115ºC for 90seconds, resulting in a PR layer about 1.3µm thick. The wafer is

A fluidic diode, valves, and a sequential-loading circuit fabricated on layered paper.

PubMed

Chen, Hong; Cogswell, Jeremy; Anagnostopoulos, Constantine; Faghri, Mohammad

2012-08-21

Current microfluidic paper-based devices lack crucial components for fluid manipulation. We created a fluidic diode fabricated entirely on a single layer of paper to control the wicking of fluids. The fluidic diode is a two-terminal component that promotes or stops wicking along a paper channel. We further constructed a trigger and a delay valve based on the fluidic diode. Furthermore, we demonstrated a high-level functional circuit, consisting of a diode and a delay valve, to manipulate two fluids in a sequential manner. Our study provides new, transformative tools to manipulate fluid in microfluidic paper-based devices.

Untangling the proximate causes and underlying drivers of deforestation and forest degradation in Myanmar.

PubMed

Lim, Cheng Ling; Prescott, Graham W; De Alban, Jose Don T; Ziegler, Alan D; Webb, Edward L

2017-12-01

Political transitions often trigger substantial environmental changes. In particular, deforestation can result from the complex interplay among the components of a system-actors, institutions, and existing policies-adapting to new opportunities. A dynamic conceptual map of system components is particularly useful for systems in which multiple actors, each with different worldviews and motivations, may be simultaneously trying to alter different facets of the system, unaware of the impacts on other components. In Myanmar, a global biodiversity hotspot with the largest forest area in mainland Southeast Asia, ongoing political and economic reforms are likely to change the dynamics of deforestation drivers. A fundamental conceptual map of these dynamics is therefore a prerequisite for interventions to reduce deforestation. We used a system-dynamics approach and causal-network analysis to determine the proximate causes and underlying drivers of forest loss and degradation in Myanmar from 1995 to 2016 and to articulate the linkages among them. Proximate causes included infrastructure development, timber extraction, and agricultural expansion. These were stimulated primarily by formal agricultural, logging, mining, and hydropower concessions and economic investment and social issues relating to civil war and land tenure. Reform of land laws, the link between natural resource extraction and civil war, and the allocation of agricultural concessions will influence the extent of future forest loss and degradation in Myanmar. The causal-network analysis identified priority areas for policy interventions, for example, creating a public registry of land-concession holders to deter corruption in concession allocation. We recommend application of this analytical approach to other countries, particularly those undergoing political transition, to inform policy interventions to reduce forest loss and degradation. © 2017 The Authors. Conservation Biology published by Wiley Periodicals, Inc. on behalf of Society for Conservation Biology.

MAP3K11/GDF15 axis is a critical driver of cancer cachexia

PubMed Central

Tao, Julie; Liu, Qing; Nicoletti, Richard; Feng, Bin; Krieger, Brian; Mazsa, Elizabeth; Siddiquee, Zakir; Wang, Ruoji; Huang, Lucia; Shen, Luhua; Lin, Jie; Vigano, Antonio; Chiu, M. Isabel; Weng, Zhigang; Winston, William; Weiler, Solly

2015-01-01

Abstract Background Cancer associated cachexia affects the majority of cancer patients during the course of the disease and thought to be directly responsible for about a quarter of all cancer deaths. Current evidence suggests that a pro‐inflammatory state may be associated with this syndrome although the molecular mechanisms responsible for the development of cachexia are poorly understood. The purpose of this work was the identification of key drivers of cancer cachexia that could provide a potential point of intervention for the treatment and/or prevention of this syndrome. Methods Genetically engineered and xenograft tumour models were used to dissect the molecular mechanisms driving cancer cachexia. Cytokine profiling from the plasma of cachectic and non‐cachectic cancer patients and mouse models was utilized to correlate circulating cytokine levels with the cachexia phenotype. Results Utilizing engineered tumour models we identified MAP3K11/GDF15 pathway activation as a potent inducer of cancer cachexia. Increased expression and high circulating levels of GDF15 acted as a key mediator of this process. In animal models, tumour‐produced GDF15 was sufficient to trigger the cachexia phenotype. Elevated GDF15 circulating levels correlated with the onset and progression of cachexia in animal models and in patients with cancer. Inhibition of GDF15 biological activity with a specific antibody reversed body weight loss and restored muscle and fat tissue mass in several cachectic animal models regardless of their complex secreted cytokine profile. Conclusions The combination of correlative observations, gain of function, and loss of function experiments validated GDF15 as a key driver of cancer cachexia and as a potential therapeutic target for the treatment and/or prevention of this syndrome. PMID:27239403

Factors contributing to commercial vehicle rear-end conflicts in China: A study using on-board event data recorders.

PubMed

Bianchi Piccinini, Giulio; Engström, Johan; Bärgman, Jonas; Wang, Xuesong

2017-09-01

In the last 30years, China has undergone a dramatic increase in vehicle ownership and a resulting escalation in the number of road crashes. Although crash figures are decreasing today, they remain high; it is therefore important to investigate crash causation mechanisms to further improve road safety in China. To shed more light on the topic, naturalistic driving data was collected in Shanghai as part of the evaluation of a behavior-based safety service. The data collection included instrumenting 47 vehicles belonging to a commercial fleet with data acquisition systems. From the overall sample, 91 rear-end crash or near-crash (CNC) events, triggered by 24 drivers, were used in the analysis. The CNC were annotated by three researchers, through an expert assessment methodology based on videos and kinematic variables. The results show that the main factor behind the rear-end CNC was the adoption of very small safety margins. In contrast to results from previous studies in the US, the following vehicles' drivers typically had their eyes on the road and reacted quickly in response to the evolving conflict in most events. When delayed reactions occurred, they were mainly due to driving-related visual scanning mismatches (e.g., mirror checks) rather than visual distraction. Finally, the study identified four main conflict scenarios that represent the typical development of rear-end conflicts in this data. The findings of this study have several practical applications, such as informing the specifications of in-vehicle safety measures and automated driving and providing input into the design of coaching/training procedures to improve the driving habits of drivers. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

Characterisation of re-entrant circuit (or rotational activity) in vitro using the HL1-6 myocyte cell line.

PubMed

Houston, Charles; Tzortzis, Konstantinos N; Roney, Caroline; Saglietto, Andrea; Pitcher, David S; Cantwell, Chris D; Chowdhury, Rasheda A; Ng, Fu Siong; Peters, Nicholas S; Dupont, Emmanuel

2018-06-01

Fibrillation is the most common arrhythmia observed in clinical practice. Understanding of the mechanisms underlying its initiation and maintenance remains incomplete. Functional re-entries are potential drivers of the arrhythmia. Two main concepts are still debated, the "leading circle" and the "spiral wave or rotor" theories. The homogeneous subclone of the HL1 atrial-derived cardiomyocyte cell line, HL1-6, spontaneously exhibits re-entry on a microscopic scale due to its slow conduction velocity and the presence of triggers, making it possible to examine re-entry at the cellular level. We therefore investigated the re-entry cores in cell monolayers through the use of fluorescence optical mapping at high spatiotemporal resolution in order to obtain insights into the mechanisms of re-entry. Re-entries in HL1-6 myocytes required at least two triggers and a minimum colony area to initiate (3.5 to 6.4 mm 2 ). After electrical activity was completely stopped and re-started by varying the extracellular K + concentration, re-entries never returned to the same location while 35% of triggers re-appeared at the same position. A conduction delay algorithm also allows visualisation of the core of the re-entries. This work has revealed that the core of re-entries is conduction blocks constituted by lines and/or groups of cells rather than the round area assumed by the other concepts of functional re-entry. This highlights the importance of experimentation at the microscopic level in the study of re-entry mechanisms. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

Magnetic Flux Cancellation as the Trigger Mechanism of Solar Coronal Jets

NASA Technical Reports Server (NTRS)

McGlasson, Riley A.; Panesar, Navdeep K.; Sterling, Alphonse C.; Moore, Ronald L.

2017-01-01

Coronal jets are narrow eruptions in the solar corona, and are often observed in extreme ultraviolet (EUV) and X-Ray images. They occur everywhere on the solar disk: in active regions, quiet regions, and coronal holes (Raouafi et al. 2016). Recent studies indicate that most coronal jets in quiet regions and coronal holes are driven by the eruption of a minifilament (Sterling et al. 2015), and that this eruption follows flux cancellation at the magnetic neutral line under the pre-eruption minifilament (Panesar et al. 2016). We confirm this picture for a large sample of jets in quiet regions and coronal holes using multithermal extreme ultraviolet (EUV) images from the Solar Dynamics Observatory (SDO)/Atmospheric Imaging Assembly (AIA) and line-of-sight magnetograms from the SDO/Helioseismic and Magnetic Imager (HMI). We report observations of 60 randomly selected jet eruptions. We have analyzed the magnetic cause of these eruptions and measured the base size and the duration of each jet using routines in SolarSoft IDL. By examining the evolutionary changes in the magnetic field before, during, and after jet eruption, we found that each of these jets resulted from minifilament eruption triggered by flux cancellation at the neutral line. In agreement with the above studies, we found our jets to have an average base diameter of 7600 +/- 2700 km and an average jet-growth duration of 9.0 +/- 3.6 minutes. These observations confirm that minifilament eruption is the driver and that magnetic flux cancellation is the primary trigger mechanism for nearly all coronal hole and quiet region coronal jet eruptions.

Climate variability rather than overstocking causes recent large scale cover changes of Tibetan pastures

PubMed Central

Lehnert, L. W.; Wesche, K.; Trachte, K.; Reudenbach, C.; Bendix, J.

2016-01-01

The Tibetan Plateau (TP) is a globally important “water tower” that provides water for nearly 40% of the world’s population. This supply function is claimed to be threatened by pasture degradation on the TP and the associated loss of water regulation functions. However, neither potential large scale degradation changes nor their drivers are known. Here, we analyse trends in a high-resolution dataset of grassland cover to determine the interactions among vegetation dynamics, climate change and human impacts on the TP. The results reveal that vegetation changes have regionally different triggers: While the vegetation cover has increased since the year 2000 in the north-eastern part of the TP due to an increase in precipitation, it has declined in the central and western parts of the TP due to rising air temperature and declining precipitation. Increasing livestock numbers as a result of land use changes exacerbated the negative trends but were not their exclusive driver. Thus, we conclude that climate variability instead of overgrazing has been the primary cause for large scale vegetation cover changes on the TP since the new millennium. Since areas of positive and negative changes are almost equal in extent, pasture degradation is not generally proceeding. PMID:27073126

Climate variability rather than overstocking causes recent large scale cover changes of Tibetan pastures

NASA Astrophysics Data System (ADS)

Lehnert, L. W.; Wesche, K.; Trachte, K.; Reudenbach, C.; Bendix, J.

2016-04-01

The Tibetan Plateau (TP) is a globally important “water tower” that provides water for nearly 40% of the world’s population. This supply function is claimed to be threatened by pasture degradation on the TP and the associated loss of water regulation functions. However, neither potential large scale degradation changes nor their drivers are known. Here, we analyse trends in a high-resolution dataset of grassland cover to determine the interactions among vegetation dynamics, climate change and human impacts on the TP. The results reveal that vegetation changes have regionally different triggers: While the vegetation cover has increased since the year 2000 in the north-eastern part of the TP due to an increase in precipitation, it has declined in the central and western parts of the TP due to rising air temperature and declining precipitation. Increasing livestock numbers as a result of land use changes exacerbated the negative trends but were not their exclusive driver. Thus, we conclude that climate variability instead of overgrazing has been the primary cause for large scale vegetation cover changes on the TP since the new millennium. Since areas of positive and negative changes are almost equal in extent, pasture degradation is not generally proceeding.

Flip-chip bonded optoelectronic integration based on ultrathin silicon (UTSi) CMOS

NASA Astrophysics Data System (ADS)

Hong, Sunkwang; Ho, Tawei; Zhang, Liping; Sawchuk, Alexander A.

2003-06-01

We describe the design and test of flip-chip bonded optoelectronic CMOS devices based on Peregrine Semiconductor's 0.5 micron Ultra-Thin Silicon on sapphire (UTSi) technology. The UTSi process eliminates the substrate leakage that typically results in crosstalk and reduces parasitic capacitance to the substrate, providing many benefits compared to bulk silicon CMOS. The low-loss synthetic sapphire substrate is optically transparent and has a coefficient of thermal expansion suitable for flip-chip bonding of vertical cavity surface emitting lasers (VCSELs) and detectors. We have designed two different UTSi CMOS chips. One contains a flip-chip bonded 1 x 4 photodiode array, a receiver array, a double edge triggered D-flip flop-based 2047-pattern pseudo random bit stream (PRBS) generator and a quadrature-phase LC-voltage controlled oscillator (VCO). The other chip contains a flip-chip bonded 1 x 4 VCSEL array, a driver array based on high-speed low-voltage differential signals (LVDS) and a full-balanced differential LC-VCO. Each VCSEL driver and receiver has individual input and bias voltage adjustments. Each UTSi chip is mounted on different printed circuit boards (PCBs) which have holes with about 1 mm radius for optical output and input paths through the sapphire substrate. We discuss preliminary testing of these chips.

Experiments on Hypersonic Roughness Induced Transition by Means of Infrared Thermography

NASA Astrophysics Data System (ADS)

Schrijer, F. F. J.; Scarano, F.; van Oudheusden, B. W.; Bannink, W. J.

2005-02-01

Roughness induced boundary layer transition is experimentally investigated in the hypersonic flow regime at M = 9. The primary interest is the possible effect of stepwise geometry imperfections (2D isolated roughness) on (boundary layer) transition which may be caused on the EXPERT vehicle by the difference in thermal expansion due to the different materials used in the vehicle-nose construction. Also 3D isolated and 3D distributed roughness configurations were studied. Quantitative Infra-Red Thermography (QIRT) is used as primary diagnostic technique to measure the surface convective heat transfer and to detect boundary layer laminar-to-turbulent transition. The investigation shows that for a given height of the roughness element, the boundary layer is least sensitive to a step-like disturbance, whereas distributed 3D roughness was found to be effective in triggering transition. The experimental results have been compared to existing hypersonic transition correlations (PANT and Shuttle). Finally a transition criterion is evaluated which is based on the critical roughness height Reynolds number. Usage of this criterion enables a straightforward extrapolation to flight. Key words: hypersonic flow, boundary layer transition.

Physical modelling of LNG rollover in a depressurized container filled with water

NASA Astrophysics Data System (ADS)

Maksim, Dadonau; Denissenko, Petr; Hubert, Antoine; Dembele, Siaka; Wen, Jennifer

2015-11-01

Stable density stratification of multi-component Liquefied Natural Gas causes it to form distinct layers, with upper layer having a higher fraction of the lighter components. Heat flux through the walls and base of the container results in buoyancy-driven convection accompanied by heat and mass transfer between the layers. The equilibration of densities of the top and bottom layers, normally caused by the preferential evaporation of Nitrogen, may induce an imbalance in the system and trigger a rapid mixing process, so-called rollover. Numerical simulation of the rollover is complicated and codes require validation. Physical modelling of the phenomenon has been performed in a water-filled depressurized vessel. Reducing gas pressure in the container to levels comparable to the hydrostatic pressure in the water column allows modelling of tens of meters industrial reservoirs using a 20 cm laboratory setup. Additionally, it allows to model superheating of the base fluid layer at temperatures close the room temperature. Flow visualizations and parametric studies are presented. Results are related to outcomes of numerical modelling.

Light dosimetry for focused and defocused beam irradiation in multi-layered tissue models

NASA Astrophysics Data System (ADS)

Petrova, Kremena S.; Stoykova, Elena V.

2006-09-01

Treatment of acupuncture points, trigger points, joint inflammations in low level laser therapy as well as various applications of lasers for treatment of soft tissues in dental medicine, require irradiation by a narrow converging laser beam. The aim of this study is to compare light delivery produced by focused or defocused narrow beam irradiation in a multi-layered skin tissue model at increasing depth of the target. The task is solved by 3-D Monte-Carlo simulation for matched and mismatched refractive indices at the tissue/ambient medium interface. The modeled light beams have a circular cross-section at the tissue entrance with uniform or Gaussian intensity distribution. Three are the tissue models used in simulation : i) a bloodless skin layer; ii) a bloodless skin layer with embedded scattering object; iii) a skin layer with small blood vessels of varying size, which are modeled as infinite cylinders parallel to the tissue surface located at different depths. Optical properties (absorption coefficient, scattering coefficient, anisotropy factor, g, and index of refraction) of different tissue constituents are chosen from the literature.

Mechanistic Drivers of Reemergence of Anthropogenic Carbon in the Equatorial Pacific

NASA Astrophysics Data System (ADS)

Zhai, Ping; Rodgers, Keith B.; Griffies, Stephen M.; Slater, Richard D.; Iudicone, Daniele; Sarmiento, Jorge L.; Resplandy, Laure

2017-09-01

Relatively rapid reemergence of anthropogenic carbon (Cant) in the Equatorial Pacific is of potential importance for its impact on the carbonate buffering capacity of surface seawater and thereby impeding the ocean's ability to further absorb Cant from the atmosphere. We explore the mechanisms sustaining Cant reemergence (upwelling) from the thermocline to surface layers by applying water mass transformation diagnostics to a global ocean/sea ice/biogeochemistry model. We find that the upwelling rate of Cant (0.4 PgC yr-1) from the thermocline to the surface layer is almost twice as large as air-sea Cant fluxes (0.203 PgC yr-1). The upwelling of Cant from the thermocline to the surface layer can be understood as a two-step process: The first being due to diapycnal diffusive transformation fluxes and the second due to surface buoyancy fluxes. We also find that this reemergence of Cant decreases dramatically during the 1982/1983 and 1997/1998 El Niño events.

Upgrade of the TOTEM DAQ using the Scalable Readout System (SRS)

NASA Astrophysics Data System (ADS)

Quinto, M.; Cafagna, F.; Fiergolski, A.; Radicioni, E.

2013-11-01

The main goals of the TOTEM Experiment at the LHC are the measurements of the elastic and total p-p cross sections and the studies of the diffractive dissociation processes. At LHC, collisions are produced at a rate of 40 MHz, imposing strong requirements for the Data Acquisition Systems (DAQ) in terms of trigger rate and data throughput. The TOTEM DAQ adopts a modular approach that, in standalone mode, is based on VME bus system. The VME based Front End Driver (FED) modules, host mezzanines that receive data through optical fibres directly from the detectors. After data checks and formatting are applied in the mezzanine, data is retransmitted to the VME interface and to another mezzanine card plugged in the FED module. The VME bus maximum bandwidth limits the maximum first level trigger (L1A) to 1 kHz rate. In order to get rid of the VME bottleneck and improve scalability and the overall capabilities of the DAQ, a new system was designed and constructed based on the Scalable Readout System (SRS), developed in the framework of the RD51 Collaboration. The project aims to increase the efficiency of the actual readout system providing higher bandwidth, and increasing data filtering, implementing a second-level trigger event selection based on hardware pattern recognition algorithms. This goal is to be achieved preserving the maximum back compatibility with the LHC Timing, Trigger and Control (TTC) system as well as with the CMS DAQ. The obtained results and the perspectives of the project are reported. In particular, we describe the system architecture and the new Opto-FEC adapter card developed to connect the SRS with the FED mezzanine modules. A first test bench was built and validated during the last TOTEM data taking period (February 2013). Readout of a set of 3 TOTEM Roman Pot silicon detectors was carried out to verify performance in the real LHC environment. In addition, the test allowed a check of data consistency and quality.

Heat-Assisted Multiferroic Solid-State Memory

PubMed Central

2017-01-01

A heat-assisted multiferroic solid-state memory design is proposed and analysed, based on a PbNbZrSnTiO3 antiferroelectric layer and Ni81Fe19 magnetic free layer. Information is stored as magnetisation direction in the free layer of a magnetic tunnel junction element. The bit writing process is contactless and relies on triggering thermally activated magnetisation switching of the free layer towards a strain-induced anisotropy easy axis. A stress is generated using the antiferroelectric layer by voltage-induced antiferroelectric to ferroelectric phase change, and this is transmitted to the magnetic free layer by strain-mediated coupling. The thermally activated strain-induced magnetisation switching is analysed here using a three-dimensional, temperature-dependent magnetisation dynamics model, based on simultaneous evaluation of the stochastic Landau-Lifshitz-Bloch equation and heat flow equation, together with stochastic thermal fields and magnetoelastic contributions. The magnetisation switching probability is calculated as a function of stress magnitude and maximum heat pulse temperature. An operating region is identified, where magnetisation switching always occurs, with stress values ranging from 80 to 180 MPa, and maximum temperatures normalised to the Curie temperature ranging from 0.65 to 0.99. PMID:28841185

Inducing electric polarization in ultrathin insulating layers

NASA Astrophysics Data System (ADS)

Martinez-Castro, Jose; Piantek, Marten; Persson, Mats; Serrate, David; Hirjibehedin, Cyrus F.

Studies of ultrathin polar oxide films have attracted the interest of researchers for a long time due to their different properties compared to bulk materials. However they present several challenges such as the difficulty in the stabilization of the polar surfaces and the limited success in tailoring their properties. Moreover, recently developed Van der Waals materials have shown that the stacking of 2D-layers trigger new collective states thanks to the interaction between layers. Similarly, interface phenomena emerge in polar oxides, like induced ferroelectricity. This represents a promising way for the creation of new materials with customized properties that differ from those of the isolated layers. Here we present a new approach for the fabrication and study of atomically thin insulating films. We show that the properties of insulating polar layers of sodium chloride (NaCl) can be engineered when they are placed on top of a charge modulated template of copper nitride (Cu2N). STM studies carried out in ultra-high vacuum and at low temperatures over NaCl/Cu2N/Cu(001) show that we are able to build up and stabilize interfaces of polar surface at the limit of one atomic layer showing new properties not present before at the atomic scale.

Heat-Assisted Multiferroic Solid-State Memory.

PubMed

Lepadatu, Serban; Vopson, Melvin M

2017-08-25

A heat-assisted multiferroic solid-state memory design is proposed and analysed, based on a PbNbZrSnTiO₃ antiferroelectric layer and Ni 81 Fe 19 magnetic free layer. Information is stored as magnetisation direction in the free layer of a magnetic tunnel junction element. The bit writing process is contactless and relies on triggering thermally activated magnetisation switching of the free layer towards a strain-induced anisotropy easy axis. A stress is generated using the antiferroelectric layer by voltage-induced antiferroelectric to ferroelectric phase change, and this is transmitted to the magnetic free layer by strain-mediated coupling. The thermally activated strain-induced magnetisation switching is analysed here using a three-dimensional, temperature-dependent magnetisation dynamics model, based on simultaneous evaluation of the stochastic Landau-Lifshitz-Bloch equation and heat flow equation, together with stochastic thermal fields and magnetoelastic contributions. The magnetisation switching probability is calculated as a function of stress magnitude and maximum heat pulse temperature. An operating region is identified, where magnetisation switching always occurs, with stress values ranging from 80 to 180 MPa, and maximum temperatures normalised to the Curie temperature ranging from 0.65 to 0.99.

Prediction of Laminar-to-Turbulent Boundary Layer Transition in Axial-Flow Turbomachinery.

DTIC Science & Technology

1981-09-01

Reynolds number. A curve fit was applied to the data of Dryden, Hall and Hislop , and Schubauer and Skramstad; the correlation was then extended to the . 24...turbulence ,~~~~1 4- . . :,7" 35 1000 900 SPONTANEOUS TRANSITION 0 800 0 SCHUBAUER AND SKRAMSTAD 8o HALL AND HISLOP o DRYDEN 700 = > 600 500 4-) C1 P 400...Engineering for Power, January, 1980 , pp. 5-12. 33. Rogler, H. L. "The Coupling Between Freestream Disturbances, Driver Oscillations, Forced

Objectives | Office of Cancer Clinical Proteomics Research

Cancer.gov

The overall objective of CPTAC is to systematically identify proteins that derive from alterations in cancer genomes and related biological processes, in order to understand the molecular basis of cancer that is not fully elucidated or not possible through genomics and to accelerate the translation of molecular findings into the clinic.  This is to be achieved through enhancing our understanding of cancer genome biology by adding a complementary functional layer of protein biology (a “proteogenome” approach) that refines/prioritizes driver genes, enhances understanding of pathogenesis

Characterization of the Time-Dependent Fluid-Structure Interaction of Passive Flow Control of Low Reynolds Number Membrane Wings

DTIC Science & Technology

2013-07-01

plates usually experiences separation near or at the leading-edge, creating an aerodynamic shear layer that either reattaches to form a separation...blunt-body shedding. At low angle-of-attack, however, flat plates do not exhibit strong blunt-body shedding, thus, is an unlikely driver. Additionally...range from 0 – 10% for typical flat plate membrane models in low-Re flow. Two distinct regions of membrane vibration relative to the tensioning

Interferometric and schlieren characterization of the plasmas and shock wave dynamics during laser-triggered discharge in atmospheric air

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wei, Wenfu; Li, Xingwen, E-mail: xwli@mail.xjtu.edu.cn; Wu, Jian

2014-08-15

This paper describes our efforts to reveal the underlying physics of laser-triggered discharges in atmospheric air using a Mach-Zehnder interferometer and schlieren photography. Unlike the hemispherical shock waves that are produced by laser ablation, bell-like morphologies are observed during laser-triggered discharges. Phase shifts are recovered from the interferograms at a time of 1000 ns by the 2D fast Fourier transform method, and then the values of the refractive index are deduced using the Abel inversion. An abundance of free electrons is expected near the cathode surface. The schlieren photographs visualize the formation of stagnation layers at ∼600 ns in the interaction zonesmore » of the laser- and discharge-produced plasmas. Multiple reflected waves are observed at later times with the development of shock wave propagations. Estimations using the Taylor-Sedov self-similar solution indicated that approximately 45.8% and 51.9% of the laser and electrical energies are transferred into the gas flow motions, respectively. Finally, numerical simulations were performed, which successfully reproduced the main features of the experimental observations, and provided valuable insights into the plasma and shock wave dynamics during the laser-triggered discharge.« less

Nuclear accumulation of the Arabidopsis immune receptor RPS4 is necessary for triggering EDS1-dependent defense.

PubMed

Wirthmueller, Lennart; Zhang, Yan; Jones, Jonathan D G; Parker, Jane E

2007-12-04

Recognition of specific pathogen molecules inside the cell by nucleotide-binding domain and leucine-rich repeat (NB-LRR) receptors constitutes an important layer of innate immunity in plants. Receptor activation triggers host cellular reprogramming involving transcriptional potentiation of basal defenses and localized programmed cell death. The sites and modes of action of NB-LRR receptors are, however, poorly understood. Arabidopsis Toll/Interleukin-1 (TIR) type NB-LRR receptor RPS4 recognizes the bacterial type III effector AvrRps4. We show that epitope-tagged RPS4 expressed under its native regulatory sequences distributes between endomembranes and nuclei in healthy and AvrRps4-triggered tissues. RPS4 accumulation in the nucleus, mediated by a bipartite nuclear localization sequence (NLS) at its C terminus, is necessary for triggering immunity through authentic activation by AvrRps4 in Arabidopsis or as an effector-independent "deregulated" receptor in tobacco. A strikingly conserved feature of TIR-NB-LRR receptors is their recruitment of the nucleocytoplasmic basal-defense regulator EDS1 in resistance to diverse pathogens. We find that EDS1 is an indispensable component of RPS4 signaling and that it functions downstream of RPS4 activation but upstream of RPS4-mediated transcriptional reprogramming in the nucleus.

Statistical distributions of avalanche size and waiting times in an inter-sandpile cascade model

NASA Astrophysics Data System (ADS)

Batac, Rene; Longjas, Anthony; Monterola, Christopher

2012-02-01

Sandpile-based models have successfully shed light on key features of nonlinear relaxational processes in nature, particularly the occurrence of fat-tailed magnitude distributions and exponential return times, from simple local stress redistributions. In this work, we extend the existing sandpile paradigm into an inter-sandpile cascade, wherein the avalanches emanating from a uniformly-driven sandpile (first layer) is used to trigger the next (second layer), and so on, in a successive fashion. Statistical characterizations reveal that avalanche size distributions evolve from a power-law p(S)≈S-1.3 for the first layer to gamma distributions p(S)≈Sαexp(-S/S0) for layers far away from the uniformly driven sandpile. The resulting avalanche size statistics is found to be associated with the corresponding waiting time distribution, as explained in an accompanying analytic formulation. Interestingly, both the numerical and analytic models show good agreement with actual inventories of non-uniformly driven events in nature.

Self-assembly of dodecaphenyl POSS thin films

NASA Astrophysics Data System (ADS)

Handke, Bartosz; Klita, Łukasz; Niemiec, Wiktor

2017-12-01

The self-assembly abilities of Dodecaphenyl Polyhedral Oligomeric Silsesquioxane thin films on Si(1 0 0) surfaces were studied. Due to their thermal properties - relatively low sublimation temperature and preservation of molecular structure - cage type silsesquioxanes are ideal material for the preparation of a thin films by Physical Vapor Deposition. The Ultra-High Vacuum environment and the deposition precision of the PVD method enable the study of early stages of thin film growth and its molecular organization. X-ray Reflectivity and Atomic Force Microscopy measurements allow to pursuit size-effects in the structure of thin films with thickness ranges from less than a single molecular layer up to several tens of layers. Thermal treatment of the thin films triggered phase change: from a poorly ordered polycrystalline film into a well-ordered multilayer structure. Self-assembly of the layers is the effect of the π-stacking of phenyl rings, which force molecules to arrange in a superlattice, forming stacks of alternating organic-inorganic layers.

Subduction of a low-salinity water mass around the Xisha Islands in the South China Sea.

PubMed

Huang, Zhida; Zhuang, Wei; Liu, Hailong; Hu, Jianyu

2018-02-15

Based on three climatologically observed temperature and salinity datasets (i.e., GDEM-V3, SCSPOD14 and WOA13), this paper reports a low-salinity (~34.32) water mass in the subsurface-to-intermediate layer around the Xisha Islands in the South China Sea. This water mass mainly subducts from the surface layer into the intermediate layer, characterized by a relatively low potential vorticity tongue extending from the bottom of mixed layer to the thermocline, and accompanied by a thermocline ventilation in spring (especially in April). The potential dynamics are the joint effects of negative wind stress curl, and an anticyclonic eddy triggered by the inherent topographic effect of the Xisha Islands, reflecting that downward vertical motion dominates the subduction. Despite lacking of the homogenous temperature and density, the low-salinity water mass is to some extent similar to the classic mode water and can be regarded as a deformed mode water in the South China Sea.

Confined Electroconvective and Flexoelectric Instabilities Deep in the Freedericksz State of Nematic CB7CB.

PubMed

Krishnamurthy, Kanakapura S; Palakurthy, Nani Babu; Yelamaggad, Channabasaveshwar V

2017-06-01

We report wormlike flexoelectric structures evolving deep in the Freedericksz state of a nematic layer of the liquid crystal cyanobiphenyl-(CH2) 7 -cyanobiphenyl. They form in the predominantly splay-bend thin boundary layers and are built up of solitary flexoelectric domains of the Bobylev-Pikin type. Their formation is possibly triggered by the gradient flexoelectric surface instability that remains optically discernible up to unusually high frequencies. The threshold voltage at which the worms form scales as square root of the frequency; in their extended state, worms often appear as labyrinthine structures on a section of loops that separate regions of opposite director deviation. Such asymmetric loops are also derived through pincement-like dissociation of ring-shaped walls. Formation of isolated domains of bulk electroconvection precedes the onset of surface instabilities. In essence, far above the Freedericksz threshold, the twisted nematic layer behaves as a combination of two orthogonally oriented planar half-layers destabilized by localized flexoelectric distortion.

Environmental drivers of epibenthic megafauna on a deep temperate continental shelf: A multiscale approach

NASA Astrophysics Data System (ADS)

Lacharité, Myriam; Metaxas, Anna

2018-03-01

Evaluating the role of abiotic factors in influencing the distribution of deep-water (>75-100 m depth) epibenthic megafaunal communities at mid-to-high latitudes is needed to estimate effects of environmental change, and support marine spatial planning since these factors can be effectively mapped. Given the disparity in scales at which these factors operate, incorporating multiple spatial and temporal scales is necessary. In this study, we determined the relative importance of 3 groups of environmental drivers at different scales (sediment, geomorphology, and oceanography) on epibenthic megafauna on a deep temperate continental shelf in the eastern Gulf of Maine (northwest Atlantic). Twenty benthic photographic transects (range: 611-1021 m; total length surveyed: 18,902 m; 996 images; average of 50 ± 16 images per transect) were performed in July and August 2009 to assess the abundance, composition and diversity of these communities. Surficial geology was assessed using seafloor imagery processed with a novel approach based on computer vision. A bathymetric terrain model (horizontal resolution: 100 m) was used to derive bathymetric variability in the vicinity of transects (1.5, 5 km). Oceanography at the seafloor (temperature, salinity, current speed, current direction) over 10 years (1999-2008) was determined using empirical (World Ocean Database 2013) and modelled data (Finite-Volume Community Ocean Model; 45 vertical layers; horizontal resolution: 1.7-9.5 km). The relative influence of environmental drivers differed between community traits. Abundance was enhanced primarily by swift current speeds, while higher diversity was observed in coarser and more heterogeneous substrates. In both cases, the role of geomorphological features was secondary to these drivers. Environmental variables were poor predictors of change in community composition at the scale of the eastern Gulf of Maine. This study demonstrated the need for explicitly incorporating scales into habitat modelling studies in these regions, and targeting specific drivers for community traits of interest.

Exploring drivers of wetland hydrologic fluxes across parameters and space

NASA Astrophysics Data System (ADS)

Jones, C. N.; Cheng, F. Y.; Mclaughlin, D. L.; Basu, N. B.; Lang, M.; Alexander, L. C.

2017-12-01

Depressional wetlands provide diverse ecosystem services, ranging from critical habitat to the regulation of landscape hydrology. The latter is of particular interest, because while hydrologic connectivity between depressional wetlands and downstream waters has been a focus of both scientific research and policy, it remains difficult to quantify the mode, magnitude, and timing of this connectivity at varying spatial and temporary scales. To do so requires robust empirical and modeling tools that accurately represent surface and subsurface flowpaths between depressional wetlands and other landscape elements. Here, we utilize a parsimonious wetland hydrology model to explore drivers of wetland water fluxes in different archetypal wetland-rich landscapes. We validated the model using instrumented sites from regions that span North America: Prairie Pothole Region (south-central Canada), Delmarva Peninsula (Mid-Atlantic Coastal Plain), and Big Cypress Swamp (southern Florida). Then, using several national scale datasets (e.g., National Wetlands Inventory, USFWS; National Hydrography Dataset, USGS; Soil Survey Geographic Database, NRCS), we conducted a global sensitivity analysis to elucidate dominant drivers of simulated fluxes. Finally, we simulated and compared wetland hydrology in five contrasting landscapes dominated by depressional wetlands: prairie potholes, Carolina and Delmarva bays, pocosins, western vernal pools, and Texas coastal prairie wetlands. Results highlight specific drivers that vary across these regions. Largely, hydroclimatic variables (e.g., PET/P ratios) controlled the timing and magnitude of wetland connectivity, whereas both wetland morphology (e.g., storage capacity and watershed size) and soil characteristics (e.g., ksat and confining layer depth) controlled the duration and mode (surface vs. subsurface) of wetland connectivity. Improved understanding of the drivers of wetland hydrologic connectivity supports enhanced, region-specific management and conservation of these critical ecosystems through more informed decision-making. Findings and conclusions expressed in this article are those of the authors and do not necessarily reflect the views or policies of the US EPA or USFWS.

Research data management and libraries: relationships, activities, drivers and influences.

PubMed

Pinfield, Stephen; Cox, Andrew M; Smith, Jen

2014-01-01

The management of research data is now a major challenge for research organisations. Vast quantities of born-digital data are being produced in a wide variety of forms at a rapid rate in universities. This paper analyses the contribution of academic libraries to research data management (RDM) in the wider institutional context. In particular it: examines the roles and relationships involved in RDM, identifies the main components of an RDM programme, evaluates the major drivers for RDM activities, and analyses the key factors influencing the shape of RDM developments. The study is written from the perspective of library professionals, analysing data from 26 semi-structured interviews of library staff from different UK institutions. This is an early qualitative contribution to the topic complementing existing quantitative and case study approaches. Results show that although libraries are playing a significant role in RDM, there is uncertainty and variation in the relationship with other stakeholders such as IT services and research support offices. Current emphases in RDM programmes are on developments of policies and guidelines, with some early work on technology infrastructures and support services. Drivers for developments include storage, security, quality, compliance, preservation, and sharing with libraries associated most closely with the last three. The paper also highlights a 'jurisdictional' driver in which libraries are claiming a role in this space. A wide range of factors, including governance, resourcing and skills, are identified as influencing ongoing developments. From the analysis, a model is constructed designed to capture the main aspects of an institutional RDM programme. This model helps to clarify the different issues involved in RDM, identifying layers of activity, multiple stakeholders and drivers, and a large number of factors influencing the implementation of any initiative. Institutions may usefully benchmark their activities against the data and model in order to inform ongoing RDM activity.

Research Data Management and Libraries: Relationships, Activities, Drivers and Influences

PubMed Central

Pinfield, Stephen; Cox, Andrew M.; Smith, Jen

2014-01-01

The management of research data is now a major challenge for research organisations. Vast quantities of born-digital data are being produced in a wide variety of forms at a rapid rate in universities. This paper analyses the contribution of academic libraries to research data management (RDM) in the wider institutional context. In particular it: examines the roles and relationships involved in RDM, identifies the main components of an RDM programme, evaluates the major drivers for RDM activities, and analyses the key factors influencing the shape of RDM developments. The study is written from the perspective of library professionals, analysing data from 26 semi-structured interviews of library staff from different UK institutions. This is an early qualitative contribution to the topic complementing existing quantitative and case study approaches. Results show that although libraries are playing a significant role in RDM, there is uncertainty and variation in the relationship with other stakeholders such as IT services and research support offices. Current emphases in RDM programmes are on developments of policies and guidelines, with some early work on technology infrastructures and support services. Drivers for developments include storage, security, quality, compliance, preservation, and sharing with libraries associated most closely with the last three. The paper also highlights a ‘jurisdictional’ driver in which libraries are claiming a role in this space. A wide range of factors, including governance, resourcing and skills, are identified as influencing ongoing developments. From the analysis, a model is constructed designed to capture the main aspects of an institutional RDM programme. This model helps to clarify the different issues involved in RDM, identifying layers of activity, multiple stakeholders and drivers, and a large number of factors influencing the implementation of any initiative. Institutions may usefully benchmark their activities against the data and model in order to inform ongoing RDM activity. PMID:25485539

Landslide trigger factors on populated, unstable slopes, Tusion, Tajikistan.

NASA Astrophysics Data System (ADS)

Domej, Gisela

2015-04-01

The Pamir region close to the Tajik-Afghan border is regularly affected by severe landslides threatening local population, their livelihood and infrastructure. In addition to landslides appearing as immediate consequence of earthquake, a high number of ground movements without previous seismic activity are also observed. The number of reported events and problem areas has strongly increased within the last ten to fifteen years. Consequently, a study was conducted to determine the triggering factors of these landslides without seismic cause. For accessibility reasons, the community of Tusion, southeast of Khorog, Gorno-Badakhshan, southern Tajikistan, where the capital township is located on a slowly moving slope, was chosen for the pilot project, and geologic mapping as well as seismic refraction and Schlumberger geoelectrics were applied. The geologic survey showed that the valley flanks around Tusion are covered with large amounts of postglacial and fluvial debris as well as moraine deposits. The absence of glacial ice and the retreat of remaining glaciers caused unstable valley flanks at many sites and, in consequence, extensive gravitational mass movements in the past, which are responsible for the today's layered ground structure as well as many secondary slumps. The latter often damage irrigation lines, which tends to further destabilize the slope. To obtain an accurate image of the superposed layers, the geophysical survey was conducted on three inhabited flanks. Arguments in favour for those three locations were not only the possibility of direct risk estimation for the region, but also the fact that the number of landslides increases constantly with population growth. Seismic and electric methods were applied in parallel to distinguish soil types and structural properties as well as to estimate the degree of water saturation. Despite of the methods' simplicity, they revealed precise explanations on triggering factors of landslides. The geophysical survey showed different density and electric conductivity regimes in the upper layers resulting from exposure and decomposition during the last centuries and especially from uncontrolled irrigation since the 1990s. The electric prospection showed a high water saturation in the weathering layers which is explained on one hand by a higher porosity of the material close to the surface, and on the other hand by the fact that crystalline rocks decompose to clay which, in turn, is able to take up water. Almost all landslides start in a depth where surveys show firstly a rapid decrease of water saturation, and secondly a transition to more compact material. Thus, it can be concluded that decomposition and irrigation provoke a (re-)activation of sliding surfaces inside the postglacial debris body. The upper layers slide on a humid surface and create the frequently observed landslides in inhabited areas.

The hydrological response to precipitations of a layered shallow sloping deposit: physical experiments and mathematical modeling

NASA Astrophysics Data System (ADS)

Damiano, Emilia; Greco, Roberto; Guida, Andrea; Olivares, Lucio; Picarelli, Luciano

2016-04-01

Although rainfall-induced landslides are frequent, so that they can be probably considered the most widespread natural hazards, fortunately the occurrence of an extreme rainfall event only rarely corresponds to the triggering of landslides. This is due to the fact that slopes, although often considered as separated systems in the stability analyses, are actually part of a larger, more complex hydrological system, with which continuously exchange water. Indeed, most of the slopes do not fail, and when they are subjected to heavy precipitation, effective draining mechanisms spontaneously develop, such as overland and subsurface runoff, and sometimes even new preferential flow paths originated by mechanical processes, such as piping erosion or deformation cracks. Hence, the triggering of a rainfall-induced landslide requires these dynamically evolving (non-linear) drainage processes to be incapable of releasing the excess of water (and pressure) accumulating within the slope. For the case of shallow sloping covers, the capability of the slope to effectively drain the infiltrating water depends on the hydraulic properties of the involved soils (hydraulic conductivity and water retention curves) and on the hydraulic boundary conditions (at the base of the cover, where it lays upon the bedrock, and at the foot of the slope), which are in turn strongly influenced by the initial moisture state (often indicated as a predisposing cause), owing to the non-linearity of the hydraulic processes. Such an already complex picture is furthermore complicated by heterogeneity. In this study, we focus our attention onto the effects of a layered soil cover with contrasting hydraulic properties on the infiltration and drainage processes in a shallow pyroclastic deposit. This is a typical situation along many pyroclastic-covered slopes of Campania (southern Italy), which present alternations of ashes (silty sands) and pumices (sands with gravel) deposited by volcanic eruptions, and where shallow landslides are sometimes triggered by intense and long-lasting precipitations. Several studies have already pointed out that layering may play a crucial role in the development of the infiltration process, as the coarse-grained pumice layers may behave as capillary barriers, leading to the formation of perched saturated zones. The hydrological behavior of such kind of layered slopes is investigated by means of small-scale infiltration experiments carried out in an instrumented flume in the laboratory. The interpretation of the experimental results is made with the help of a mathematical model of 2-D Richards equation, which allows shedding some light in the hydraulic properties of the pumices, which are hardly measurable with standard laboratory techniques. The obtained results show how, depending on initial moisture conditions, slope inclination angle and applied rainfall intensity, the response of the slope may be very different, and that the formation of a capillary barrier is not always observed.

Design, fabrication, and testing of an ultrasonic de-icing system for helicopter rotor blades

NASA Astrophysics Data System (ADS)

Palacios, Jose Luis

A low-power, non-thermal ultrasonic de-icing system is introduced as a possible substitute for current electro-thermal systems. The system generates delaminating ultrasonic transverse shear stresses at the interface of accreted ice. A PZT-4 disk driven at 28.5 KHz (radial resonance of the disk) instantaneously de-bonds 2 mm thick freezer ice layers. The ice layers are accreted to a 0.7 mm thick, 30.4 cm x 30.4 cm steel plate at an environment temperature of -20°C. A power input of 50 Watts is applied to the actuator (50 V, 19.6 KV/m), which translates to a de-icing power of 0.07 W/cm2. A finite element model of the actuator bonded to the isotropic plate is used to guide the design of the system, and predicts the transverse shear stresses at the ice interface. Wind tunnel icing tests were conducted to demonstrate the potential use of the proposed system under impact icing conditions. Both glaze ice and rime ice were generated on steel and composite plates by changing the cloud conditions of the wind tunnel. Continuous ultrasonic vibration prevented impact ice formation around the actuator location at an input power not exceeding 0.18 W/cm 2 (1.2 W/in2). As ice thickness reached a critical thickness of approximately 1.2 mm, shedding occurred on those locations where ultrasonic transverse shear stresses exceeded the shear adhesion strength of the ice. Finite element transverse shear stress predictions correlate with observed experimental impact ice de-bonding behavior. To increase the traveling distance of propagating ultrasonic waves, ultrasonic shear horizontal wave modes are studied. Wave modes providing large modal interface transverse shear stress concentration coefficients (ISCC) between the host structure (0.7 mm thick steel plate) and accreted ice (2.5 mm thick ice layer) are identified and investigated for a potential increase in the wave propagation distance. Ultrasonic actuators able to trigger these optimum wave modes are designed and fabricated. Despite exciting wave modes with high ISCC values, instantaneous ice de-bonding is not observed at input powers under 100 Watts. The two triggered ultrasonic wave modes of the structure occur at high excitation frequencies, 202 KHz and 500 KHz respectively. At these frequencies, the ultrasonic actuators do not provide large enough transverse shear stresses to exceed the shear adhesion strength of the ice layer. Neither the actuator exciting the SH1 mode (202 KHz), nor the actuator triggering the SH2 mode (500 KHz) instantaneously de-bonds ice layers with an input power under 100 Watts.

Mobile Bay river plume mixing in the inner shelf

NASA Astrophysics Data System (ADS)

Parra, S. M.; Book, J. W.; Warner, S. J.; Moum, J.

2017-12-01

The microtidal region (0.5 m spring tides) of the inner shelf outside Mobile Bay presented a complex circulation pattern driven by the pulsed river discharge and winds. Currents, salinity, temperature, and turbulence profiles were measured for up to three weeks in April 2016 at six moorings outside Mobile Bay. Currents varied between locations and with depth. During neap and spring tides the currents were reliably >0.4 and <0.4 m/s, respectively. The outflow from Mobile Bay generated a complex density circulation, where two to three layers were normally present. Multiple density layers included a thicker brackish middle layer (5-10 m thickness), and a salty bottom layer (5-10 m thickness), with a thin ( 1-3 m) freshwater surface layer found intermittently. The multilayer currents were strongest at neap tides (>0.5 m/s) and toward deeper waters, concurrent with the strongest stratification. The possible flow drivers considered include tides, winds, inertial oscillations, waves, and stratification. Turbulent kinetic energy production and dissipation were calculated with multiple methods using data from bottom-mounted, upward-looking acoustic Doppler current profilers sampling at 1 Hz, and using data from line-moored chi-pod turbulent temperature microstructure instruments sampling at 100 Hz. This work explores different forcing mechanisms involved in modulating the circulation and turbulence in a multi-layered pulsed-river inner shelf region in the Gulf of Mexico.

Hydroclimatology of Dual Peak Cholera Incidence in Bengal Region: Inferences from a Spatial Explicit Model

NASA Astrophysics Data System (ADS)

Bertuzzo, E.; Mari, L.; Righetto, L.; Casagrandi, R.; Gatto, M.; Rodriguez-Iturbe, I.; Rinaldo, A.

2010-12-01

The seasonality of cholera and its relation with environmental drivers are receiving increasing interest and research efforts, yet they remain unsatisfactorily understood. A striking example is the observed annual cycle of cholera incidence in the Bengal region which exhibits two peaks despite the main environmental drivers that have been linked to the disease (air and sea surface temperature, zooplankton density, river discharge) follow a synchronous single-peak annual pattern. A first outbreak, mainly affecting the coastal regions, occurs in spring and it is followed, after a period of low incidence during summer, by a second, usually larger, peak in autumn also involving regions situated farther inland. A hydroclimatological explanation for this unique seasonal cycle has been recently proposed: the low river spring flows favor the intrusion of brackish water (the natural environment of the causative agent of the disease) which, in turn, triggers the first outbreak. The summer rising river discharges have a temporary dilution effect and prompt the repulsion of contaminated water which lowers the disease incidence. However, the monsoon flooding, together with the induced crowding of the population and the failure of the sanitation systems, can possibly facilitate the spatial transmission of the disease and promote the autumn outbreak. We test this hypothesis using a mechanistic, spatially explicit model of cholera epidemic. The framework directly accounts for the role of the river network in transporting and redistributing cholera bacteria among human communities as well as for the annual fluctuation of the river flow. The model is forced with the actual environmental drivers of the region, namely river flow and temperature. Our results show that these two drivers, both having a single peak in the summer, can generate a double peak cholera incidence pattern. Besides temporal patterns, the model is also able to qualitatively reproduce spatial patterns characterized by a spring peak confined to the coastal area and a autumn peak involving the whole region. The modeling exercise allows to identify the relevant processes and to understand how they concert to the generation of this peculiar pattern. Finally, the range of epidemiological and hydrological conditions under which dual or a single peaks are expected is quantified.

Community Health Workers as Drivers of a Successful Community-Based Disease Management Initiative

PubMed Central

Peretz, Patricia J.; Matiz, Luz Adriana; Findley, Sally; Lizardo, Maria; Evans, David; McCord, Mary

2012-01-01

In 2005, local leaders in New York City developed the Washington Heights/Inwood Network for Asthma Program to address the burden of asthma in their community. Bilingual community health workers based in community organizations and the local hospital provided culturally appropriate education and support to families who needed help managing asthma. Families participating in the yearlong care coordination program received comprehensive asthma education, home environmental assessments, trigger reduction strategies, and clinical and social referrals. Since 2006, 472 families have enrolled in the yearlong program. After 12 months, hospitalizations and emergency department visits decreased by more than 50%, and caregiver confidence in controlling the child's asthma increased to nearly 100%. Key to the program's success was the commitment and involvement of community partners from program inception to date. PMID:22515859

PPARγ in emphysema: blunts the damage and triggers repair?

PubMed Central

Kelly, Neil J.; Shapiro, Steven D.

2014-01-01

Cigarette smoke is the most common cause of pulmonary emphysema, which results in an irreversible loss of lung structure and function. Th1 and Th17 immune responses have been implicated in emphysema pathogenesis; however, the drivers of emphysema-associated immune dysfunction are not fully understood. In this issue of the JCI, Shan and colleagues found that peroxisome proliferator–activated receptor γ (PPARγ) is downregulated in APCs isolated from the lungs of emphysematous chronic smokers and mice exposed to cigarette smoke. Furthermore, treatment with a PPARγ agonist prevented emphysema development and appeared to reduce emphysema-associated lung volume expansion in mice exposed to cigarette smoke. Further work will need to be done to evaluate the potential of PPARγ agonists to restore lung capacity in emphysematous patients. PMID:24569365

Platelet bioreactor-on-a-chip

PubMed Central

Mazutis, Linas; Wu, Stephen; Sylman, Joanna L.; Ehrlicher, Allen; Machlus, Kellie R.; Feng, Qiang; Lu, Shijiang; Lanza, Robert; Neeves, Keith B.; Weitz, David A.; Italiano, Joseph E.

2014-01-01

Platelet transfusions total >2.17 million apheresis-equivalent units per year in the United States and are derived entirely from human donors, despite clinically significant immunogenicity, associated risk of sepsis, and inventory shortages due to high demand and 5-day shelf life. To take advantage of known physiological drivers of thrombopoiesis, we have developed a microfluidic human platelet bioreactor that recapitulates bone marrow stiffness, extracellular matrix composition, micro-channel size, hemodynamic vascular shear stress, and endothelial cell contacts, and it supports high-resolution live-cell microscopy and quantification of platelet production. Physiological shear stresses triggered proplatelet initiation, reproduced ex vivo bone marrow proplatelet production, and generated functional platelets. Modeling human bone marrow composition and hemodynamics in vitro obviates risks associated with platelet procurement and storage to help meet growing transfusion needs. PMID:25606631

Community health workers as drivers of a successful community-based disease management initiative.

PubMed

Peretz, Patricia J; Matiz, Luz Adriana; Findley, Sally; Lizardo, Maria; Evans, David; McCord, Mary

2012-08-01

In 2005, local leaders in New York City developed the Washington Heights/Inwood Network for Asthma Program to address the burden of asthma in their community. Bilingual community health workers based in community organizations and the local hospital provided culturally appropriate education and support to families who needed help managing asthma. Families participating in the yearlong care coordination program received comprehensive asthma education, home environmental assessments, trigger reduction strategies, and clinical and social referrals. Since 2006, 472 families have enrolled in the yearlong program. After 12 months, hospitalizations and emergency department visits decreased by more than 50%, and caregiver confidence in controlling the child's asthma increased to nearly 100%. Key to the program's success was the commitment and involvement of community partners from program inception to date.

Characterization of LiBC by phase-contrast scanning transmission electron microscopy.

PubMed

Krumeich, Frank; Wörle, Michael; Reibisch, Philipp; Nesper, Reinhard

2014-08-01

LiBC was used as a model compound for probing the applicability of phase-contrast (PC) imaging in an aberration-corrected scanning transmission electron microscope (STEM) to visualize lithium distributions. In the LiBC structure, boron and carbon are arranged to hetero graphite layers between which lithium is incorporated. The crystal structure is reflected in the PC-STEM images recorded perpendicular to the layers. The experimental images and their defocus dependence match with multi-slice simulations calculated utilizing the reciprocity principle. The observation that a part of the Li positions is not occupied is likely an effect of the intense electron beam triggering Li displacement. Copyright © 2013 Elsevier Ltd. All rights reserved.

Apparatus for coating a surface with a metal utilizing a plasma source

DOEpatents

Brown, I.G.; MacGill, R.A.; Galvin, J.E.

1991-05-07

An apparatus and method are disclosed for coating or layering a surface with a metal utilizing a metal vapor vacuum arc plasma source. The apparatus includes a trigger mechanism for actuating the metal vacuum vapor arc plasma source in a pulsed mode at a predetermined rate. The surface or substrate to be coated or layered is supported in position with the plasma source in a vacuum chamber. The surface is electrically biased for a selected period of time during the pulsed mode of operation of the plasma source. Both the pulsing of the metal vapor vacuum arc plasma source and the electrical biasing of the surface are synchronized for selected periods of time. 10 figures.

Apparatus for coating a surface with a metal utilizing a plasma source

DOEpatents

Brown, Ian G.; MacGill, Robert A.; Galvin, James E.

1991-01-01

An apparatus and method for coating or layering a surface with a metal utilizing a metal vapor vacuum arc plasma source. The apparatus includes a trigger mechanism for actuating the metal vacuum vapor arc plasma source in a pulsed mode at a predetermined rate. The surface or substrate to be coated or layered is supported in position with the plasma source in a vacuum chamber. The surface is electrically biased for a selected period of time during the pulsed mode of operation of the plasma source. Both the pulsing of the metal vapor vacuum arc plasma source and the electrical biasing of the surface are synchronized for selected periods of time.

Swellable clay minerals in weathering products of volcanic sediments related to landslides by 2016 Kumamoto Earthquake

NASA Astrophysics Data System (ADS)

Isobe, H.; Torii, M.

2016-12-01

2016 Kumamoto Earthquake triggered numerous landslides in Aso caldera area, Japan and incurred heavy casualties. Landslides occurred not only on steep slopes at the caldera cliffs or the barranco but also on relatively gradual slopes at the side of the central cones in the Aso caldera. The Aso volcano is a volcanic complex with huge caldera formed by catastrophic eruption at approximately 90ka and central cones formed by subsequent activities to recent years. The central cones are volcanic peaks contain various rocks including basaltic, andesitic and rhoyolitic lavas and pyroclastic materials. In this study, we analyzed the samples collected from the bottom surface of landslides occurred at the gradual hillside on the western flank of the Aso central cones. The subsurface geology of the site is Takanoobane rhyolite lava, 51ka, covered by dark silty or pelitic tuffs and black soil strata including Kusasenri pumice layer, 31ka. The bottom plane of the landslides can be seen as flat surfaces at boundaries between units in the Kusasenri pumice or bottom of the Kusasenri pumice on the pelitic tuff with charcoaled plants. The Kusasenri pumice layer is a coarse grained and highly permeable but poorly continuous. X-ray diffraction analysis revealed that the main component of the samples is halloysite (10Å). Halloysite (10Å) is alteration product of fine grained volcanic ash, and swellable clay with interlayer water molecules which bring sticky and deformable characteristics. The landslides caused by 2016 Kumamoto Earthquake occurred without precipitation within a week. Strong earthquake may fluidize swellable clay layers in gradual slopes and triggered heavy landslides.

Was the extreme and wide-spread marine oil-snow sedimentation and flocculent accumulation (MOSSFA) event during the Deepwater Horizon blow-out unique?

PubMed

Vonk, Sophie M; Hollander, David J; Murk, AlberTinka J

2015-11-15

During the Deepwater Horizon blowout, thick layers of oiled material were deposited on the deep seafloor. This large scale benthic concentration of oil is suggested to have occurred via the process of Marine Oil Snow Sedimentation and Flocculent Accumulation (MOSSFA). This meta-analysis investigates whether MOSSFA occurred in other large oil spills and identifies the main drivers of oil sedimentation. MOSSFA was found to have occurred during the IXTOC I blowout and possibly during the Santa Barbara blowout. Unfortunately, benthic effects were not sufficiently studied for the 52 spills we reviewed. However, based on the current understanding of drivers involved, we conclude that MOSSFA and related benthic contamination may be widespread. We suggest to collect and analyze sediment cores at specific spill locations, as improved understanding of the MOSSFA process will allow better informed spill responses in the future, taking into account possible massive oil sedimentation and smothering of (deep) benthic ecosystems. Copyright © 2015 Elsevier Ltd. All rights reserved.

Tree water relations can trigger monoterpene emissions from Scots pine stems during spring recovery

NASA Astrophysics Data System (ADS)

Vanhatalo, A.; Chan, T.; Aalto, J.; Korhonen, J. F.; Kolari, P.; Hölttä, T.; Nikinmaa, E.; Bäck, J.

2015-09-01

Tree canopies are known to emit large amounts of VOCs (volatile organic compounds) such as monoterpenes into the surrounding air. High VOC emission rates from boreal forests have been observed during the transition from winter to summer activity. The most important sources of these are considered to be the green foliage, understory vegetation and soil organisms, but emissions from the living stand woody compartments have so far not been quantified. We analyzed whether the non-foliar components could partially explain the springtime high emission rates. We measured the monoterpene emissions from Scots pine (Pinus sylvestris L.) stem and shoots during the dehardening phase of trees in field conditions in two consecutive springs. We observed a large, transient monoterpene burst from the stem, while the shoot monoterpene emissions remained low. The burst lasted about 12 h. Simultaneously, an unusual nighttime sap flow and a non-systematic diurnal pattern of tree diameter were detected. Hence, we suggest that the monoterpene burst was a consequence of the recovery of the stem from wintertime, and likely related to the refilling of embolized tracheids and/or phenological changes in the living cells of the stem. This indicates that the dominant processes and environmental drivers triggering the monoterpene emissions are different between the stem and the foliage.

Natural wind variability triggered drop in German redispatch volume and costs from 2015 to 2016

PubMed Central

Reyers, Mark; Märker, Carolin; Witthaut, Dirk

2018-01-01

Avoiding dangerous climate change necessitates the decarbonization of electricity systems within the next few decades. In Germany, this decarbonization is based on an increased exploitation of variable renewable electricity sources such as wind and solar power. While system security has remained constantly high, the integration of renewables causes additional costs. In 2015, the costs of grid management saw an all time high of about € 1 billion. Despite the addition of renewable capacity, these costs dropped substantially in 2016. We thus investigate the effect of natural climate variability on grid management costs in this study. We show that the decline is triggered by natural wind variability focusing on redispatch as a main cost driver. In particular, we find that 2016 was a weak year in terms of wind generation averages and the occurrence of westerly circulation weather types. Moreover, we show that a simple model based on the wind generation time series is skillful in detecting redispatch events on timescales of weeks and beyond. As a consequence, alterations in annual redispatch costs in the order of hundreds of millions of euros need to be understood and communicated as a normal feature of the current system due to natural wind variability. PMID:29329349

The nature of conflict in palliative care: A qualitative exploration of the experiences of staff and family members.

PubMed

François, Karemah; Lobb, Elizabeth; Barclay, Sarah; Forbat, Liz

2017-08-01

Conflict is a significant and recurring problem in healthcare. This study aimed to understand staff and relatives' perspectives on the characteristics of conflict and serious disagreement in adult palliative care, including triggers, risk factors and the impact on themselves and clinical care. Qualitative study of 25 staff and seven bereaved relatives using individual interviews, recruited from a multidisciplinary specialist palliative care setting in Australia. Data were analysed thematically. Communication was frequently cited as a cause of conflict. Further, different understandings regarding disease process, syringe drivers and providing nutrition/hydration caused conflict. Staff applied empathy to moderate their responses to conflict. Relatives' reactions to conflict followed a trend of anger/frustration followed by explanations or justifications of the conflict. Relatives identified systemic rather than interpersonal issues as triggering conflict. The data illustrate connections with conflict literature in other clinical areas, but also points of convergence such as the compassion shown by both families and staff, and the identification of systemic rather than always individual causes. Family meetings may fruitfully be applied to prevent and de-escalate conflict. Clinical audits may be useful to identify and provide support to families where there may be unresolved conflict impacting grief process. Copyright © 2017 Elsevier B.V. All rights reserved.

Clinical and Pathophysiological Overview of Acinetobacter Infections: a Century of Challenges

PubMed Central

Nielsen, Travis B.; Bonomo, Robert A.; Pantapalangkoor, Paul; Luna, Brian; Spellberg, Brad

2016-01-01

SUMMARY Acinetobacter is a complex genus, and historically, there has been confusion about the existence of multiple species. The species commonly cause nosocomial infections, predominantly aspiration pneumonia and catheter-associated bacteremia, but can also cause soft tissue and urinary tract infections. Community-acquired infections by Acinetobacter spp. are increasingly reported. Transmission of Acinetobacter and subsequent disease is facilitated by the organism's environmental tenacity, resistance to desiccation, and evasion of host immunity. The virulence properties demonstrated by Acinetobacter spp. primarily stem from evasion of rapid clearance by the innate immune system, effectively enabling high bacterial density that triggers lipopolysaccharide (LPS)–Toll-like receptor 4 (TLR4)-mediated sepsis. Capsular polysaccharide is a critical virulence factor that enables immune evasion, while LPS triggers septic shock. However, the primary driver of clinical outcome is antibiotic resistance. Administration of initially effective therapy is key to improving survival, reducing 30-day mortality threefold. Regrettably, due to the high frequency of this organism having an extreme drug resistance (XDR) phenotype, early initiation of effective therapy is a major clinical challenge. Given its high rate of antibiotic resistance and abysmal outcomes (up to 70% mortality rate from infections caused by XDR strains in some case series), new preventative and therapeutic options for Acinetobacter spp. are desperately needed. PMID:27974412

Development and test of the DAQ system for a Micromegas prototype to be installed in the ATLAS experiment

NASA Astrophysics Data System (ADS)

Bianco, M.; Martoiu, S.; Sidiropoulou, O.; Zibell, A.

2015-12-01

A Micromegas (MM) quadruplet prototype with an active area of 0.5 m2 that adopts the general design foreseen for the upgrade of the innermost forward muon tracking systems (Small Wheels) of the ATLAS detector in 2018-2019, has been built at CERN and is going to be tested in the ATLAS cavern environment during the LHC RUN-II period 2015-2017. The integration of this prototype detector into the ATLAS data acquisition system using custom ATCA equipment is presented. An ATLAS compatible Read Out Driver (ROD) based on the Scalable Readout System (SRS), the Scalable Readout Unit (SRU), will be used in order to transmit the data after generating valid event fragments to the high-level Read Out System (ROS). The SRU will be synchronized with the LHC bunch crossing clock (40.08 MHz) and will receive the Level-1 trigger signals from the Central Trigger Processor (CTP) through the TTCrx receiver ASIC. The configuration of the system will be driven directly from the ATLAS Run Control System. By using the ATLAS TDAQ Software, a dedicated Micromegas segment has been implemented, in order to include the detector inside the main ATLAS DAQ partition. A full set of tests, on the hardware and software aspects, is presented.

Biodegradable protein-based rockets for drug transportation and light-triggered release.

PubMed

Wu, Zhiguang; Lin, Xiankun; Zou, Xian; Sun, Jianmin; He, Qiang

2015-01-14

We describe a biodegradable, self-propelled bovine serum albumin/poly-l-lysine (PLL/BSA) multilayer rocket as a smart vehicle for efficient anticancer drug encapsulation/delivery to cancer cells and near-infrared light controlled release. The rockets were constructed by a template-assisted layer-by-layer assembly of the PLL/BSA layers, followed by incorporation of a heat-sensitive gelatin hydrogel containing gold nanoparticles, doxorubicin, and catalase. These rockets can rapidly deliver the doxorubicin to the targeted cancer cell with a speed of up to 68 μm/s, through a combination of biocatalytic bubble propulsion and magnetic guidance. The photothermal effect of the gold nanoparticles under NIR irradiation enable the phase transition of the gelatin hydrogel for rapid release of the loaded doxorubicin and efficient killing of the surrounding cancer cells. Such biodegradable and multifunctional protein-based microrockets provide a convenient and efficient platform for the rapid delivery and controlled release of therapeutic drugs.

Structure of Rotavirus Outer-Layer Protein VP7 Bound with a Neutralizing Fab

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aoki, Scott T.; Settembre, Ethan C.; Trask, Shane D.

2009-06-17

Rotavirus outer-layer protein VP7 is a principal target of protective antibodies. Removal of free calcium ions (Ca{sup 2+}) dissociates VP7 trimers into monomers, releasing VP7 from the virion, and initiates penetration-inducing conformational changes in the other outer-layer protein, VP4. We report the crystal structure at 3.4 angstrom resolution of VP7 bound with the Fab fragment of a neutralizing monoclonal antibody. The Fab binds across the outer surface of the intersubunit contact, which contains two Ca{sup 2+} sites. Mutations that escape neutralization by other antibodies suggest that the same region bears the epitopes of most neutralizing antibodies. The monovalent Fab ismore » sufficient to neutralize infectivity. We propose that neutralizing antibodies against VP7 act by stabilizing the trimer, thereby inhibiting the uncoating trigger for VP4 rearrangement. A disulfide-linked trimer is a potential subunit immunogen.« less

How Does Tropical Cyclone Size Affect the Onset Timing of Secondary Eyewall Formation?

NASA Astrophysics Data System (ADS)

Guan, Liang; Ge, Xuyang

2018-02-01

By using idealized numerical simulations, the impact of tropical cyclone size on secondary eyewall formation (SEF) is examined. Both unbalanced boundary layer and balanced processes are examined to reveal the underlying mechanism. The results show that a tropical cyclone (TC) with a larger initial size favors a quicker SEF and a larger outer eyewall. For a TC with a larger initial size, it will lead to a stronger surface entropy flux, and thus more active outer convection. Meanwhile, a greater inertial stability helps the conversion from diabatic heating to kinetic energy. Furthermore, the progressively broadening of the tangential wind field will induce significant boundary layer imbalances. This unbalanced boundary layer process results in a supergradient wind zone that acts as an important mechanism for triggering and maintaining deep convection. In short, different behaviors of balanced and unbalanced processes associated with the initial wind profile lead to different development rates of the secondary eyewall.

Seasonal, inter-annual and decadal drivers of tree and grass productivity in an Australian tropical savanna.

NASA Astrophysics Data System (ADS)

Moore, C.; Beringer, J.; Hutley, L. B.; Evans, B. J.; Tapper, N. J.; Donohue, R. J.; Exbrayat, J. F.

2016-12-01

Tree-grass savannas are a widespread biome and are highly valued for their ecosystem services. Natural or anthropogenic shifts in the savanna tree-grass ratio have wide-reaching implications for food production, timber harvesting, biodiversity, the water cycle and carbon sequestration. It is important to understand the long-term dynamics and drivers of both tree and grass productivity separately, in order to successfully manage savannas in the future. This study investigates the inter-annual variability (IAV) of tree (overstory) and grass (understory) productivity at the Howard Springs OzFlux/Fluxnet site by combining a long-term (15 year) eddy covariance flux record and DIFFUSE model estimates of tree and grass productivity inferred from satellite remote sensing. On a seasonal basis, the primary drivers of overstory and understory productivity were solar radiation in the wet season and soil moisture in the dry season, with deeper soil layers becoming more important as the dry season progressed. On an inter-annual basis, variability in the amount of annual rainfall and length of the rainy season determined soil water availability, which had a positive effect on overstory productivity and a negative effect on understory productivity. No linear trend in the tree-grass ratio was observed over the 15-year study period, indicating that woody encroachment was not occurring to a significant degree at the study site. However, the tree-grass ratio was well correlated with modes of climate variability, namely the Southern Oscillation Index. This study has provided important insight into the long-term contributions of trees and grasses to savanna productivity, along with the respective drivers of IAV. The results will contribute towards model development and building better links with remote sensing techniques in order to more comprehensively monitor savanna structure and function across space and time.

Impact craters and landslide volume distribution in Valles Marineris, Mars

NASA Astrophysics Data System (ADS)

De Blasio, Fabio

2014-05-01

The landslides in the wide gorge system of Valles Marineris (Mars) exhibit volumes of the or-der of several hundred 1,000 km3 and runouts often in the excess of 80 km. Most landslides have occurred at the borders of the valleys, where the unbalanced weight of the 5-8 km high headwalls has been evidently sufficient to cause instability. Previous analysis has shown that the mechanical conditions of instability would not have been reached without external triggering fac-tors, if the wallslope consisted of intact rock. Among the factors that have likely promoted instability, we are currently analyzing: i) the possibility of rock weakening due to weathering; ii) the alternation of weak layers within more massive rock; weak layers might for example due to evaporites, the possible presence of ice table at some depth, or water; iii) weakening due to impact damage prior to the formation of Valles Marineris; studies of impact craters on Earth show that the volumes of damaged rock extends much deeper than the crater itself; iv) direct triggering of a landslide due to the seismic waves generated by a large meteoroid impact in the vicinity, and v) direct triggering of a landslide con-sequent to impact at the headwall, with impulsive release of momentum and short but intense increase of the triggering force. We gathered a large database for about 3000 Martian landslides that allow us to infer some of their statistical properties supporting our analyses, and especially to discriminate among some of the above listed predisposing and triggering factors. In particular, we analyse in this contribution the frequency distribution of landslide volumes starting from the assumption that these events are controlled by the extent of the shock damage zones. Relative position of the impact point and damage zones with respect to the Valles Marineris slopes could in fact control the released volumes. We perform 3D slope stability analy-sis under different geometrical constraints (e.g. crater size and position, slope angle and height, size of the relative shock damage zone) starting from rock mass properties calibrated in a previous study (Crosta et al., 2014). We report about the synthetic volume frequency distribution gen-erated by considering the most critical failure surfaces for the different geometrical constraints and the frequency distribution of craters on Mars surface (e.g., Hartmann and Neukum, 2001). 1. Crosta, G.B., Utili, S., De Blasio, F.V., Castellanza, R. (2014)Reassessing rock mass properties and slope instability triggering conditions in Valles Marineris, Mars.Earth Planetary Science Letters, 338, 329-343. http://dx.doi.org/10.1016/j.epsl.2013.11.053 2. Hartmann, W., and Neukum, G., (2001). Crater Chronology and the evolution of Mars. Space Science Reviews 96: 165-194.

Full-scale physical model of landslide triggering

NASA Astrophysics Data System (ADS)

Lora, M.; Camporese, M.; Salandin, P.

2013-12-01

Landslide triggering induced by high-intensity rainfall infiltration in hillslopes is a complex phenomenon that involves hydrological processes operating at different spatio-temporal scales. Empirical methods give rough information about landslide-prone areas, without investigating the theoretical framework needed to achieve an in-depth understanding of the involved physical processes. In this study, we tackle this issue through physical experiments developed in an artificial hillslope realized in the Department of Civil, Environmental and Architectural Engineering of the University of Padua. The structure consists of a reinforced concrete box containing a soil prism with the following maximum dimensions: 3.5 m high, 6 m long, and 2 m wide. In order to analyze and examine the triggered failure state, the experiments are carried out with intensive monitoring of pore water pressure and moisture content response. Subsurface monitoring instruments are installed at several locations and depths to measure downward infiltration and/or a rising groundwater table. We measure the unsaturated soil water pressure as well as positive pore pressures preceding failure in each experiments with six tensiometers. The volumetric water content is determined through six Time Domain Reflectometry probes. Two pressure transducers are located in observation wells to determine the position of the water table in time. Two stream gauges are positioned at the toeslope, for measuring both runoff and subsurface outflow. All data are collected and recorded by an acquisition data system from Campbell Scientific. The artificial hillslope is characterized by well-known and controlled conditions, which are designed to reproduce an ideal set-up susceptible to heavy rainfall landslide. The hydrologic forcing is generated by a rainfall simulator realized with nozzles from Sprying System and. specifically designed to produce a spatially uniform rainfall of intensity ranging from 50 to 150 mm/h. The aim of our experiments is to reproduce the instability trigger that occurs in saturated or partially unsaturated conditions depending on the specific characteristics of the soil and its initial conditions; the retention curve of fine sand and the initial porosity are taken into account to highlight the hydrological condition of the surface layer during the trigger occurrence. Through our experimental setup we can investigate the succession of phases and their magnitude that cause the landslide trigger, in order to understand the instability mechanism that heavy rainfall can induce in fine sandy hillslopes. Particular attention is given on the role of water pressure head, not only with respect to the violation of Coulomb failure within a sloping soil, but also with respect to the subsequent deformation that involves the upper hillslope layers. In particular, we report here on the characterization of the sandy terrain used in the experiments and the preliminary results, together with a first discussion of the observed data.

Importance of the Gulf of Mexico as a climate driver for U.S. severe thunderstorm activity

NASA Astrophysics Data System (ADS)

Molina, M. J.; Timmer, R. P.; Allen, J. T.

2016-12-01

Different features of the Gulf of Mexico (GOM), such as the Loop Current and warm-core rings, are found to influence monthly-to-seasonal severe weather occurrence in different regions of the United States (U.S.). The warmer (cooler) the GOM sea surface temperatures, the more (less) hail and tornadoes occur during March-May over the southern U.S. This pattern is reflected physically in boundary layer specific humidity and mixed-layer convective available potential energy, two large-scale atmospheric conditions favorable for severe weather occurrence. This relationship is complicated by interactions between the GOM and El Niño-Southern Oscillation (ENSO) but persists when analyzing ENSO neutral conditions. This suggests that the GOM can influence hail and tornado occurrence and provides another source of regional predictability for seasonal severe weather.

[PVFS 2000: An operational parallel file system for Beowulf

NASA Technical Reports Server (NTRS)

Ligon, Walt

2004-01-01

The approach has been to develop Parallel Virtual File System version 2 (PVFS2) , retaining the basic philosophy of the original file system but completely rewriting the code. It shows the architecture of the server and client components. BMI - BMI is the network abstraction layer. It is designed with a common driver and modules for each protocol supported. The interface is non-blocking, and provides mechanisms for optimizations including pinning user buffers. Currently TCP/IP and GM(Myrinet) modules have been implemented. Trove -Trove is the storage abstraction layer. It provides for storing both data spaces and name/value pairs. Trove can also be implemented using different underlying storage mechanisms including native files, raw disk partitions, SQL and other databases. The current implementation uses native files for data spaces and Berkeley db for name/value pairs.

pH-Triggered SERS via Modulated Plasmonic Coupling in Individual Bimetallic Nanocobs

DTIC Science & Technology

2011-01-01

dry states. In contrast with previous examples of such bimetallic nano- cobs, we utilize here a responsive polyacrylic acid (PAA) nanocoating that...Moreover, placing nanoparticles inside a polymer- gel layer in close proximity to the nanowire surface effectively prevents any potential aggregation of...unexpected result even for gel materials. This expanded state allowed for observation of the molecular ordering in the swollen-dried state (Figure 3

Bidirectional Hebbian Plasticity Induced by Low-Frequency Stimulation in Basal Dendrites of Rat Barrel Cortex Layer 5 Pyramidal Neurons.

PubMed

Díez-García, Andrea; Barros-Zulaica, Natali; Núñez, Ángel; Buño, Washington; Fernández de Sevilla, David

2017-01-01

According to Hebb's original hypothesis (Hebb, 1949), synapses are reinforced when presynaptic activity triggers postsynaptic firing, resulting in long-term potentiation (LTP) of synaptic efficacy. Long-term depression (LTD) is a use-dependent decrease in synaptic strength that is thought to be due to synaptic input causing a weak postsynaptic effect. Although the mechanisms that mediate long-term synaptic plasticity have been investigated for at least three decades not all question have as yet been answered. Therefore, we aimed at determining the mechanisms that generate LTP or LTD with the simplest possible protocol. Low-frequency stimulation of basal dendrite inputs in Layer 5 pyramidal neurons of the rat barrel cortex induces LTP. This stimulation triggered an EPSP, an action potential (AP) burst, and a Ca 2+ spike. The same stimulation induced LTD following manipulations that reduced the Ca 2+ spike and Ca 2+ signal or the AP burst. Low-frequency whisker deflections induced similar bidirectional plasticity of action potential evoked responses in anesthetized rats. These results suggest that both in vitro and in vivo similar mechanisms regulate the balance between LTP and LTD. This simple induction form of bidirectional hebbian plasticity could be present in the natural conditions to regulate the detection, flow, and storage of sensorimotor information.

Impact of topography on the diurnal cycle of summertime moist convection in idealized simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hassanzadeh, Hanieh; Schmidli, Jürg; Langhans, Wolfgang

The impact of an isolated mesoscale mountain on the diurnal cycle of moist convection and its spatial variation is investigated. Convection-resolving simulations of flow over 3D Gaussian-shaped mountains are performed for a conditionally unstable atmosphere under diurnal radiative forcing. The results show considerable spatial variability in terms of timing and amount of convective precipitation. This variability relates to different physical mechanisms responsible for convection initiation in different parts of the domain. During the late morning, the mass convergence from the radiatively driven diurnal upslope flow confronting the large-scale incident background flow triggers strong convective precipitation over the mountain lee slope.more » As a consequence, instabilities in the boundary layer are swept out by the emerging cold pool in the vicinity of the mountain, and some parts over the mountain near-field receive less rainfall than the far-field. Over the latter, an unperturbed boundary-layer growth allows for sporadic convective initiation. Still, secondary convection triggered over the leading edge of the cold pool spreads some precipitation over the downstream near-field. Detailed analysis of our control simulation provides further explanation of this frequently observed precipitation pattern over mountains and adjacent plains. Sensitivity experiments indicate a significant influence of the mountain height on the precipitation pattern over the domain.« less

SABRE: a bio-inspired fault-tolerant electronic architecture.

PubMed

Bremner, P; Liu, Y; Samie, M; Dragffy, G; Pipe, A G; Tempesti, G; Timmis, J; Tyrrell, A M

2013-03-01

As electronic devices become increasingly complex, ensuring their reliable, fault-free operation is becoming correspondingly more challenging. It can be observed that, in spite of their complexity, biological systems are highly reliable and fault tolerant. Hence, we are motivated to take inspiration for biological systems in the design of electronic ones. In SABRE (self-healing cellular architectures for biologically inspired highly reliable electronic systems), we have designed a bio-inspired fault-tolerant hierarchical architecture for this purpose. As in biology, the foundation for the whole system is cellular in nature, with each cell able to detect faults in its operation and trigger intra-cellular or extra-cellular repair as required. At the next level in the hierarchy, arrays of cells are configured and controlled as function units in a transport triggered architecture (TTA), which is able to perform partial-dynamic reconfiguration to rectify problems that cannot be solved at the cellular level. Each TTA is, in turn, part of a larger multi-processor system which employs coarser grain reconfiguration to tolerate faults that cause a processor to fail. In this paper, we describe the details of operation of each layer of the SABRE hierarchy, and how these layers interact to provide a high systemic level of fault tolerance.

Impact of topography on the diurnal cycle of summertime moist convection in idealized simulations

DOE PAGES

Hassanzadeh, Hanieh; Schmidli, Jürg; Langhans, Wolfgang; ...

2015-08-31

The impact of an isolated mesoscale mountain on the diurnal cycle of moist convection and its spatial variation is investigated. Convection-resolving simulations of flow over 3D Gaussian-shaped mountains are performed for a conditionally unstable atmosphere under diurnal radiative forcing. The results show considerable spatial variability in terms of timing and amount of convective precipitation. This variability relates to different physical mechanisms responsible for convection initiation in different parts of the domain. During the late morning, the mass convergence from the radiatively driven diurnal upslope flow confronting the large-scale incident background flow triggers strong convective precipitation over the mountain lee slope.more » As a consequence, instabilities in the boundary layer are swept out by the emerging cold pool in the vicinity of the mountain, and some parts over the mountain near-field receive less rainfall than the far-field. Over the latter, an unperturbed boundary-layer growth allows for sporadic convective initiation. Still, secondary convection triggered over the leading edge of the cold pool spreads some precipitation over the downstream near-field. Detailed analysis of our control simulation provides further explanation of this frequently observed precipitation pattern over mountains and adjacent plains. Sensitivity experiments indicate a significant influence of the mountain height on the precipitation pattern over the domain.« less

Bidirectional Hebbian Plasticity Induced by Low-Frequency Stimulation in Basal Dendrites of Rat Barrel Cortex Layer 5 Pyramidal Neurons

PubMed Central

Díez-García, Andrea; Barros-Zulaica, Natali; Núñez, Ángel; Buño, Washington; Fernández de Sevilla, David

2017-01-01

According to Hebb's original hypothesis (Hebb, 1949), synapses are reinforced when presynaptic activity triggers postsynaptic firing, resulting in long-term potentiation (LTP) of synaptic efficacy. Long-term depression (LTD) is a use-dependent decrease in synaptic strength that is thought to be due to synaptic input causing a weak postsynaptic effect. Although the mechanisms that mediate long-term synaptic plasticity have been investigated for at least three decades not all question have as yet been answered. Therefore, we aimed at determining the mechanisms that generate LTP or LTD with the simplest possible protocol. Low-frequency stimulation of basal dendrite inputs in Layer 5 pyramidal neurons of the rat barrel cortex induces LTP. This stimulation triggered an EPSP, an action potential (AP) burst, and a Ca2+ spike. The same stimulation induced LTD following manipulations that reduced the Ca2+ spike and Ca2+ signal or the AP burst. Low-frequency whisker deflections induced similar bidirectional plasticity of action potential evoked responses in anesthetized rats. These results suggest that both in vitro and in vivo similar mechanisms regulate the balance between LTP and LTD. This simple induction form of bidirectional hebbian plasticity could be present in the natural conditions to regulate the detection, flow, and storage of sensorimotor information. PMID:28203145

Assessing the indirect effects due to natural hazards on a mesoscale

NASA Astrophysics Data System (ADS)

Pfurtscheller, C.; Schwarze, R.

2009-04-01

Measuring indirect economic costs and other effects from natural hazards, especially floods in alpine and other mountainous regions, are a necessary part of a comprehensive economic assessment. Their omission seriously affects the relative economic benefits of structural or non structural measures of flood defence. Surpassing controversial, IO-model-based economic estimates, analysing indirect economic effects lead to the key question of identifying and evaluating the drivers of indirect economic effects and resilience to system effects in the regional economy, i.e. at the meso-level. This investigation takes place for the catastrophic floods in summer 2005 in the provinces of Tyrol and Vorarlberg, Austria, which caused an estimated € 670 Mio direct loss on private and public assets and severe interruptions in lifeline services. The paper starts out with differentiating the concept of indirect economic costs from direct costs, examing different temporal (short vs. long-term) and spatial (macro-, meso- vs. microeconomic) system boundaries. It surveys common theories of economic resilience and vulnerability at the regional economy level. Indirect effects at the regional economy level can be defined as interferences of the economic exchange of goods and services triggered by breakdowns of transport lines and critical production inputs. The extent and persistence of indirect effects of natural hazards is not only by parameters of the extreme event, such as duration and amplitude of the flood, but much more by resilience parameters of the regional economy such as size of enterprises, the network structure (linkages) of the regional economy, availability of insurance and relief funds, and the stock of inventory. These effects can only be dissected by means of expert judgement and event studies. This paper presents the results of a survey conducted among business practioneers, members of chamber of commerce, civil protection agencies to identify and scale the drivers of indirect costs triggered by floods on a local and regional scale. We develop a risk point scale and explain how it can be nested into IO-model-based economic tools such as the HAZUS indirect economic loss calculator

Recalibration of the earthworm tier 1 risk assessment of plant protection products.

PubMed

Christl, Heino; Bendall, Julie; Bergtold, Matthias; Coulson, Mike; Dinter, Axel; Garlej, Barbara; Hammel, Klaus; Kabouw, Patrick; Sharples, Amanda; von Mérey, Georg; Vrbka, Silvie; Ernst, Gregor

2016-10-01

In the first step of earthworm risk assessment for plant protection products (PPPs), the risk is assessed by comparing the no-observed effect levels (NOELs) from laboratory reproduction tests with the predicted exposure of the PPP in soil, while applying a trigger value (assessment factor [AF]) to cover uncertainties. If this step indicates a potential risk, field studies are conducted. However, the predicted environmental concentration in soil, which can be calculated, for example, for different soil layers (ranging from 0-1 cm to 0-20 cm), and the AF determine the conservatism that is applied in this first step. In this review paper, the tier 1 earthworm risk assessment for PPPs is calibrated by comparing the NOEL in earthworm reproduction tests with effect levels on earthworm populations under realistic field conditions. A data set of 54 pairs of studies conducted in the laboratory and in the field with the same PPP was compiled, allowing a direct comparison of relevant endpoints. The results indicate that a tier 1 AF of 5 combined with a regulatory relevant soil layer of 0 to 5 cm provides a conservative tier 1 risk assessment. A risk was identified by the tier 1 risk assessment in the majority of the cases at application rates that were of low risk for natural earthworm populations under field conditions. Increasing the conservatism in the tier 1 risk assessment by reducing the depth of the regulatory relevant soil layer or by increasing the tier 1 AF would increase the number of false positives and trigger a large number of additional field studies. This increased conservatism, however, would not increase the margin of safety for earthworm populations. The analysis revealed that the risk assessment is conservative if an AF of 5 and a regulatory relevant soil layer of 0 to 5 cm is used. Integr Environ Assess Manag 2016;12:643-650. © 2015 SETAC. © 2015 SETAC.

Disease-related amyloidogenic variants of human lysozyme trigger the unfolded protein response and disturb eye development in Drosophila melanogaster

PubMed Central

Kumita, Janet R.; Helmfors, Linda; Williams, Jocy; Luheshi, Leila M.; Menzer, Linda; Dumoulin, Mireille; Lomas, David A.; Crowther, Damian C.; Dobson, Christopher M.; Brorsson, Ann-Christin

2012-01-01

We have created a Drosophila model of lysozyme amyloidosis to investigate the in vivo behavior of disease-associated variants. To achieve this objective, wild-type (WT) protein and the amyloidogenic variants F57I and D67H were expressed in Drosophila melanogaster using the UAS-gal4 system and both the ubiquitous and retinal expression drivers Act5C-gal4 and gmr-gal4. The nontransgenic w1118 Drosophila line was used as a control throughout. We utilized ELISA experiments to probe lysozyme protein levels, scanning electron microscopy for eye phenotype classification, and immunohistochemistry to detect the unfolded protein response (UPR) activation. We observed that expressing the destabilized F57I and D67H lysozymes triggers UPR activation, resulting in degradation of these variants, whereas the WT lysozyme is secreted into the fly hemolymph. Indeed, the level of WT was up to 17 times more abundant than the variant proteins. In addition, the F57I variant gave rise to a significant disruption of the eye development, and this correlated to pronounced UPR activation. These results support the concept that the onset of familial amyloid disease is linked to an inability of the UPR to degrade completely the amyloidogenic lysozymes prior to secretion, resulting in secretion of these destabilized variants, thereby leading to deposition and associated organ damage.—Kumita, J. R., Helmfors, L., Williams, J., Luheshi, L. M., Menzer, L., Dumoulin, M., Lomas, D. A., Crowther, D. C., Dobson, C. M., Brorsson, A.-C. Disease-related amyloidogenic variants of human lysozyme trigger the unfolded protein response and disturb eye development in Drosophila melanogaster. PMID:21965601

Investigation of the process chain leading to the development of convection during COP IOP 4b

NASA Astrophysics Data System (ADS)

Bauer, H.-S.; Schwitalla, T.; Aoshima, F.; Behrendt, A.; Wulfmeyer, V.

2012-04-01

The COPS IOP 4b took place from June 20th to June 21st 2007. It was characterized by widespread convection in the COPS domain. The development was steered by a strong low pressure system southwest of the British Isles. On its eastern side warm and moist subtropical air was directed to central Europe. First convection was triggered over the Vosges Mountains around noon on the 20th of June long before the front approached the COPS region. After a calm early afternoon, severe convection was triggered in wide regions of the COPS region in the evening and moved eastwards to Bavaria during the night to the 21st of June. In contrast to other IOPs, the situation was not captured correctly by most of the involved prediction models, no matter whether they were operated with or without sophisticated data assimilation. Aim of this presentation is to unravel the mechanisms responsible for the triggering of convection and to understand the processes preparing the atmosphere for the development of severe convection during the afternoon and night. For this purpose, many different data sets will be investigated ranging from the high resolution Vienna Enhanced Resolution Analysis (VERA), high resolution radar and satellite images and composites to soundings and data as well as retrieved products from the instruments at the COPS supersites. First impression is that the complicated low-level wind field is the major driver for the preparation of the atmosphere and therefore for the development of convection during the day. The inaccuracies in representing the low level wind field are also expected to be the major reason for the failure of the models to correctly predict the situation.

Magnetic Flux Cancellation as the Trigger of Solar Coronal Jets

NASA Astrophysics Data System (ADS)

McGlasson, R.; Panesar, N. K.; Sterling, A. C.; Moore, R. L.

2017-12-01

Coronal jets are narrow eruptions in the solar corona, and are often observed in extreme ultraviolet (EUV) and X-ray images. They occur everywhere on the solar disk: in active regions, quiet regions, and coronal holes (Raouafi et al. 2016). Recent studies indicate that most coronal jets in quiet regions and coronal holes are driven by the eruption of a minifilament (Sterling et al. 2015), and that this eruption follows flux cancellation at the magnetic neutral line under the pre-eruption minifilament (Panesar et al. 2016). We confirm this picture for a large sample of jets in quiet regions and coronal holes using multithermal (304 Å 171 Å, 193 Å, and 211 Å) extreme ultraviolet (EUV) images from the Solar Dynamics Observatory (SDO) /Atmospheric Imaging Assembly (AIA) and line-of-sight magnetograms from the SDO /Helioseismic and Magnetic Imager (HMI). We report observations of 60 randomly selected jet eruptions. We have analyzed the magnetic cause of these eruptions and measured the base size and the duration of each jet using routines in SolarSoft IDL. By examining the evolutionary changes in the magnetic field before, during, and after jet eruption, we found that each of these jets resulted from minifilament eruption triggered by flux cancellation at the neutral line. In agreement with the above studies, we found our jets to have an average base diameter of 7600 ± 2700 km and an average duration of 9.0 ± 3.6 minutes. These observations confirm that minifilament eruption is the driver and magnetic flux cancellation is the primary trigger mechanism for nearly all coronal hole and quiet region coronal jet eruptions.

Holocene tsunamigenic sediments and tsunami modelling in the Thermaikos Gulf area (northern Greece)

NASA Astrophysics Data System (ADS)

Reicherter, Klaus; Papanikolaou, Ioannis D.; Roger, Jean; Grützner, Christoph; Stamatis, Georgios; Papanikolaou, Dimitrios

2010-05-01

Shallow drill cores in flat and southerly exposed coastal areas around the Thermaikos Gulf (Thessalonica, northern Greece) provided evidence for past high energy sedimentary events, which are interpreted as tsunamites. A tsunamigenic source is located along the western tip of the North Anatolian Fault Zone (NAFZ) in the North Aegean Basin, where water depths ranging between 1.200 and 1.650 m are sufficiently deep to generate tsunamis. However, the event layers up to now cannot be assigned to individual seismic or landslide sources, but the potential of a tsunami threat in the Thermaikos Gulf area can now be tested, following both sedimentological and modelling processes. Such potential threat regarding the Thermaikos Gulf has only recently been notified but never tested and studied in depth. As a result, several Holocene coarse clastic layers have been found intercalated in clayey or gypsiferous lagoonal deposits. These layers have erosive bases, show fining-up and thinning-up sequences, and include shell debris, foraminifera and rip-up clasts of lagoonal sediments. A widely observed significant feature of these layers involves mud-coated beach clasts, clasts that rework the high-plasticity clays of lagoons. Such features that indicate highly disturbed sedimentological condition (hyperpyncal flows) are rarely described elsewhere. Multiple intercalations of these layers with all the mentioned indicative features downhole are interpreted paleotsunami deposits from tsunamis generated by earthquakes or earthquake-triggered submarine landslides triggered by seismic shaking in the Thermaikos Gulf. Modelling of the tsunami potential of the basin-bounding fault southwards of the Thermaikos Gulf provides an example for possible tsunami generation at only one segment of NAFZ along an approx. 55 km normal fault at the southern fault-bound margin of the North Aegean Basin. The Herodotus Histories report on inundations and sea withdrawals occurring during the Greek-Persian war, which occurred near Potidea. In the ancient Greek village Mende we found evidence for a tsunamigenic layer, dated with shells to 2500 BP, which may tentatively be interpreted as the sedimentary remains of the "Herodotus tsunami" in 479 BC. Acknowledgements: This work has been supported financially by the DAAD-IKYDA Project (Tracing tsunami deposits in the Thermaikos Gulf, Northern Greece. Implications for seismic and tsunami hazard and archaeology) and the RWTH Aachen University.

Redox responsive nanotubes from organometallic polymers by template assisted layer by layer fabrication

NASA Astrophysics Data System (ADS)

Song, Jing; Jańczewski, Dominik; Guo, Yuanyuan; Xu, Jianwei; Vancso, G. Julius

2013-11-01

Redox responsive nanotubes were fabricated by the template assisted layer-by-layer (LbL) assembly method and employed as platforms for molecular payload release. Positively and negatively charged organometallic poly(ferrocenylsilane)s (PFS) were used to construct the nanotubes, in combination with other polyions. During fabrication, multilayers of these polyions were deposited onto the inner pores of template porous membranes, followed by subsequent removal of the template. Anodized porous alumina and track-etched polycarbonate membranes were used as templates. The morphology, electrochemistry, composition and other properties of the obtained tubular structure were characterized by fluorescence microscopy, scanning (SEM) and transmission electron microscopy (TEM) and energy-dispersive X-ray (EDX) spectroscopy. Composite nanotubes, consisting of poly(acrylic acid) anions with PFS+ and nanoparticles including fluorophore labelled dextran and decorated quantum dots, with PFS polyelectrolytes were also fabricated, broadening the scope of the structures. Cyclic voltammograms of PFS containing nanotubes showed similar redox responsive behaviour to thin LbL assembled films. Redox triggered release of labelled macromolecules from these tubular structures demonstrated application potential in controlled molecular delivery.Redox responsive nanotubes were fabricated by the template assisted layer-by-layer (LbL) assembly method and employed as platforms for molecular payload release. Positively and negatively charged organometallic poly(ferrocenylsilane)s (PFS) were used to construct the nanotubes, in combination with other polyions. During fabrication, multilayers of these polyions were deposited onto the inner pores of template porous membranes, followed by subsequent removal of the template. Anodized porous alumina and track-etched polycarbonate membranes were used as templates. The morphology, electrochemistry, composition and other properties of the obtained tubular structure were characterized by fluorescence microscopy, scanning (SEM) and transmission electron microscopy (TEM) and energy-dispersive X-ray (EDX) spectroscopy. Composite nanotubes, consisting of poly(acrylic acid) anions with PFS+ and nanoparticles including fluorophore labelled dextran and decorated quantum dots, with PFS polyelectrolytes were also fabricated, broadening the scope of the structures. Cyclic voltammograms of PFS containing nanotubes showed similar redox responsive behaviour to thin LbL assembled films. Redox triggered release of labelled macromolecules from these tubular structures demonstrated application potential in controlled molecular delivery. Electronic supplementary information (ESI) available: Nanotube wall thickness determination protocol. See DOI: 10.1039/c3nr03927g

Mechanisms affecting the transition from shallow to deep convection over land: Inferences from observations collected at the ARM Southern Great Plains site

NASA Astrophysics Data System (ADS)

Zhang, Y.; Klein, S. A.

2009-12-01

11 years of summertime observations at the Atmospheric Radiation Measurement (ARM) Climate Research Facility Southern Great Plains (SGP) site are used to investigate mechanisms controlling the transition from shallow to deep convection over land. A more humid environment above the boundary layer favors the occurrence of late-afternoon heavy precipitation events. The higher moisture content is brought by wind from south. Greater boundary layer inhomogeneity in moist static energy (MSE) is correlated to larger rain rates at the initial stage of precipitation. MSE inhomogeneity is attributed to both moisture and temperature fields, and is correlated with westerly winds. In an examination of afternoon rain statistics, higher relative humidity above the boundary layer is correlated to an earlier onset and longer duration of precipitation, while greater boundary layer inhomogeneity and atmospheric instability are positively correlated to the total rain amount and the maximum rain rate. On balance, these observations favor theories for the transition that involve a moist free troposphere and boundary layer heterogeneity in preference to those that involve convective available potential energy or convective inhibition. Thus the evidence presented here supports the current emphasis in the modeling community on the entraining nature of convection and the role of boundary layer cold pools in triggering new convection.

Dynamics of Complex Systems Built as Coupled Physical, Communication and Decision Layers

PubMed Central

Kühnlenz, Florian; Nardelli, Pedro H. J.

2016-01-01

This paper proposes a simple model to capture the complexity of multilayer systems where their constituent layers affect, and are affected by, each other. The physical layer is a circuit composed by a power source and resistors in parallel. Every individual agent aims at maximizing its own delivered power by adding, removing or keeping the resistors it has; the delivered power is in turn a non-linear function that depends on the other agents’ behavior, its own internal state, its global state perception, the information received from its neighbors via the communication network and a randomized selfishness. We develop an agent-based simulation to analyze the effects of number of agents (system size), communication network topology, communication errors and the minimum power gain that triggers a behavioral change on the system dynamic. Our results show that a wave-like behavior at macro-level (caused by individual changes in the decision layer) can only emerge for a specific system size. The ratio between cooperators and defectors depends on the minimum gain assumed—lower minimal gains lead to less cooperation, and vice-versa. Different communication network topologies imply different levels of power utilization and fairness at the physical layer, and a certain level of error in the communication layer induces more cooperation. PMID:26730590

Small-scale impacts as potential trigger for landslides on small Solar system bodies

NASA Astrophysics Data System (ADS)

Hofmann, Marc; Sierks, Holger; Blum, Jürgen

2017-07-01

We conducted a set of experiments to investigate whether millimetre-sized impactors impinging on a granular material at several m s-1 are able to trigger avalanches on small, atmosphereless planetary bodies. These experiments were carried out at the Zentrum für angewandte Raumfahrttechnologie und Mikrogravitation (ZARM) drop tower facility in Bremen, Germany to facilitate a reduced gravity environment. Additional data were gathered at Earth gravity levels in the laboratory. As sample materials we used a ground Howardites, Eucrites and Diogenites (HED) meteorite and the Johnson Space Center (JSC) Mars-1 Martian soil simulant. We found that this type of small-scale impact can trigger avalanches with a moderate probability, if the target material is tilted to an angle close to the angle of repose. We additionally simulated a small-scale impact using the discrete element method code esys-particle. These simulations show that energy transfer from impactor to the target material is most efficient at low- and moderate-impactor inclinations and the transferred energy is retained in particles close to the surface due to a rapid dissipation of energy in lower material layers driven by inelastic collisions. Through Monte Carlo simulations we estimate the time-scale on which small-scale impacts with the observed characteristics will trigger avalanches covering all steep slopes on the surface of a small planetary body to be of the order 105 yr.

Observing Physical and Biological Drivers of pH and O2 in a Seasonal Ice Zone in the Ross Sea Using Profiling Float Data

NASA Astrophysics Data System (ADS)

Briggs, E.; Martz, T. R.; Talley, L. D.; Mazloff, M. R.

2015-12-01

Ice cover has strong influence over gas exchange, vertical stability, and biological production which are critical to understanding the Southern Ocean's central role in oceanic biogeochemical cycling and heat and carbon uptake under a changing climate. However the relative influence of physical versus biological processes in this hard-to-study region is poorly understood due to limited observations. Here we present new findings from a profiling float equipped with biogeochemical sensors in the seasonal ice zone of the Ross Sea capturing, for the first time, under-ice pH profile data over a two year timespan from 2014 to the present. The relative influence of physical (e.g. vertical mixing and air-sea gas exchange) and biological (e.g. production and respiration) drivers of pH and O2 within the mixed layer are explored during the phases of ice formation, ice cover, and ice melt over the two seasonal cycles. During the austral fall just prior to and during ice formation, O2 increases as expected due to surface-layer undersaturation and enhanced gas exchange. A small increase in pH is also observed during this phase, but without a biological signal in accompanying profiling float chlorophyll data, which goes against common reasoning from both a biological and physical standpoint. During the phase of ice cover, gas exchange is inhibited and a clear respiration signal is observed in pH and O2 data from which respiration rates are calculated. In the austral spring, ice melt gives rise to substantial ice edge phytoplankton blooms indicated by O2 supersaturation and corresponding increase in pH and large chlorophyll signal. The influence of the duration of ice cover and mixed layer depth on the magnitude of the ice edge blooms is explored between the two seasonal cycles.

Self-Propagating Combustion Triggered Synthesis of 3D Lamellar Graphene/BaFe12O19 Composite and Its Electromagnetic Wave Absorption Properties

PubMed Central

Zhao, Tingkai; Ji, Xianglin; Jin, Wenbo; Yang, Wenbo; Peng, Xiarong; Duan, Shichang; Dang, Alei; Li, Hao; Li, Tiehu

2017-01-01

The synthesis of 3D lamellar graphene/BaFe12O19 composites was performed by oxidizing graphite and sequentially self-propagating combustion triggered process. The 3D lamellar graphene structures were formed due to the synergistic effect of the tremendous heat induced gasification as well as huge volume expansion. The 3D lamellar graphene/BaFe12O19 composites bearing 30 wt % graphene present the reflection loss peak at −27.23 dB as well as the frequency bandwidth at 2.28 GHz (< −10 dB). The 3D lamellar graphene structures could consume the incident waves through multiple reflection and scattering within the layered structures, prolonging the propagation path of electromagnetic waves in the absorbers. PMID:28336889

Binary selectable detector holdoff circuit: Design, testing, and application. [to laser radar data acquisition system

NASA Technical Reports Server (NTRS)

Kadrmas, K. A.

1973-01-01

A very high speed switching circuit, part of a laser radar data acquisition system, has been designed and tested. The primary function of this circuit was to provide computer controlled switching of photodiode detector preamplifier power supply voltages, typically less than plus or minus 20 volts, in approximately 10 nanoseconds. Thus, in actual use, detector and/or detector preamplifier damage can be avoided as a result of sudden extremely large values of backscattered radiation being detected, such as might be due to short range, very thin atmospheric dust layers. Switching of the power supply voltages was chosen over direct switching the photodiode detector input to the preamplifier, based on system noise considerations. Also, the circuit provides a synchronized trigger pulse output for triggering devices such as the Biomation Model 8100 100 MHz analog to digital converter.

Adjacent Vehicle Number-Triggered Adaptive Transmission for V2V Communications.

PubMed

Wei, Yiqiao; Chen, Jingjun; Hwang, Seung-Hoon

2018-03-02

For vehicle-to-vehicle (V2V) communication, such issues as continuity and reliability still have to be solved. Specifically, it is necessary to consider a more scalable physical layer due to the high-speed mobility of vehicles and the complex channel environment. Adaptive transmission has been adapted in channel-dependent scheduling. However, it has been neglected with regards to the physical topology changes in the vehicle network. In this paper, we propose a physical topology-triggered adaptive transmission scheme which adjusts the data rate between vehicles according to the number of connectable vehicles nearby. Also, we investigate the performance of the proposed method using computer simulations and compare it with the conventional methods. The numerical results show that the proposed method can provide more continuous and reliable data transmission for V2V communications.

Adjacent Vehicle Number-Triggered Adaptive Transmission for V2V Communications

PubMed Central

Wei, Yiqiao; Chen, Jingjun

2018-01-01

For vehicle-to-vehicle (V2V) communication, such issues as continuity and reliability still have to be solved. Specifically, it is necessary to consider a more scalable physical layer due to the high-speed mobility of vehicles and the complex channel environment. Adaptive transmission has been adapted in channel-dependent scheduling. However, it has been neglected with regards to the physical topology changes in the vehicle network. In this paper, we propose a physical topology-triggered adaptive transmission scheme which adjusts the data rate between vehicles according to the number of connectable vehicles nearby. Also, we investigate the performance of the proposed method using computer simulations and compare it with the conventional methods. The numerical results show that the proposed method can provide more continuous and reliable data transmission for V2V communications. PMID:29498646

The theory of planned behavior, materialism, and aggressive driving.

PubMed

Efrat, Kalanit; Shoham, Aviv

2013-10-01

Aggressive driving is a growing problem worldwide. Previous research has provided us with some insights into the characteristics of drivers prone to aggressiveness on the road and into the external conditions triggering such behavior. Little is known, however, about the personality traits of aggressive drivers. The present study proposes planned behavior and materialism as predictors of aggressive driving behavior. Data was gathered using a questionnaire-based survey of 220 individuals from twelve large industrial organizations in Israel. Our hypotheses were tested using structural equation modeling. Our results indicate that while planned behavior is a good predictor of the intention to behave aggressively, it has no impact on the tendency to behave aggressively. Materialism, however, was found to be a significant indicator of aggressive driving behavior. Our study is based on a self-reported survey, therefore might suffer from several issues concerning the willingness to answer truthfully. Furthermore, the sampling group might be seen as somewhat biased due to the relatively high income/education levels of the respondents. While both issues, aggressive driving and the theory of planned behavior, have been studied previously, the linkage between the two as well as the ability of materialism to predict aggressive behavior received little attention previously. The present study encompasses these constructs providing new insights into the linkage between them. Copyright © 2013 Elsevier Ltd. All rights reserved.

Climate warming and humans played different roles in triggering Late Quaternary extinctions in east and west Eurasia

PubMed Central

Wan, Xinru

2017-01-01

Climate change and humans are proposed as the two key drivers of total extinction of many large mammals in the Late Pleistocene and Early Holocene, but disentangling their relative roles remains challenging owing to a lack of quantitative evaluation of human impact and climate-driven distribution changes on the extinctions of these large mammals in a continuous temporal–spatial dimension. Here, our analyses showed that temperature change had significant effects on mammoth (genus Mammuthus), rhinoceros (Rhinocerotidae), horse (Equidae) and deer (Cervidae). Rapid global warming was the predominant factor driving the total extinction of mammoths and rhinos in frigid zones from the Late Pleistocene and Early Holocene. Humans showed significant, negative effects on extirpations of the four mammalian taxa, and were the predominant factor causing the extinction or major extirpations of rhinos and horses. Deer survived both rapid climate warming and extensive human impacts. Our study indicates that both the current rates of warming and range shifts of species are much faster than those from the Late Pleistocene to Holocene. Our results provide new insight into the extinction of Late Quaternary megafauna by demonstrating taxon-, period- and region-specific differences in extinction drivers of climate change and human disturbances, and some implications about the extinction risk of animals by recent and ongoing climate warming. PMID:28330916

Development of a hybrid mode linear transformer driver stage

NASA Astrophysics Data System (ADS)

Zhang, Le; Wang, Meng; Zhou, Liangji; Tian, Qing; Guo, Fan; Wang, Lingyun; Qing, Yanling; Zhao, Yue; Dai, Yingmin; Han, Wenhui; Chen, Lin; Xie, Weiping

2018-02-01

At present, the mainstream technologies of primary power sources of large pulse power devices adopt Marx or linear transformer driver (LTD) designs. Based on the analysis of the characteristics of these two types of circuit topologies, the concept of a hybrid mode LTD stage based on Marx branches is proposed. The analysis shows that the hybrid mode LTD stage can realize the following goals: (a) to reduce the energy and power handled by the basic components (switch and capacitor) to lengthen their lifetime; (b) to reduce the requirements of the multipath synchronous trigger system; and (c) to improve the maintainability of the LTD stage by using independent Marx generators instead of "traditional LTD bricks." To verify the technique, a hybrid mode LTD stage consisting of 50 branches (four-stage compact Marx generators) was designed, manufactured and tested. The stage has a radius of about 3.3 m and a height of 0.6 m. The single Marx circuit's load current is about 21 kA, with a rise time of ˜90 ns (10%-90%), under the conditions of capacitors charged to ±40 kV and a 6.9 Ω matched load. The whole stage's load current is ˜1 MA , with a rise time of ˜112 ns (10%-90%), when the capacitors are charged to ±45 kV and the matched load is 0.14 Ω .

A palaeo-ecological assessment of the resilience of south-east Asian dry forests to monsoon extremes

NASA Astrophysics Data System (ADS)

Hamilton, R. J.; Penny, D.; Maxwell, A.

2014-12-01

Predictions that the frequency and intensity of monsoon extremes will rise in coming decades are being made with increasing confidence. There is concern that these climatic changes may drive tropical monsoon forests across critical thresholds, triggering ecological regime shifts. The global consequences of such shifts, coupled with knowledge gaps around the nature and intensity of drivers needed to instigate ecosystem reorganization, highlights the need for research that analyses the resilience of these seasonal forest to future climatic change. While work has indicated that these forests may be susceptible to reorganization to savanna under changing precipitation regimes, the interactions between climatic drivers and ecosystem response is still poorly understood, particularly in the seasonal forests outside of the neo- and afro-tropics. This study presents results on the threshold dynamics of the extensive south-east Asian seasonally dry tropical forest ecoregion (SASDTF) through analysis of plant microfossils and charcoal archived in sediment cores extracted from two tropical crater lakes in Cambodia. These data are compared with regional paleoclimatic reconstructions to gauge past forest response to monsoon extremes, and provide insight into the magnitude and duration of climatic events most likely to result in the breaching of critical thresholds. Our results suggest that, at a biome level, the SASDTF appears resilient to low-amplitude climatic variations over millennia, despite instrumental observations of strong precipitation-tree cover coupling in global dry forest resilience models.

Climate warming and humans played different roles in triggering Late Quaternary extinctions in east and west Eurasia.

PubMed

Wan, Xinru; Zhang, Zhibin

2017-03-29

Climate change and humans are proposed as the two key drivers of total extinction of many large mammals in the Late Pleistocene and Early Holocene, but disentangling their relative roles remains challenging owing to a lack of quantitative evaluation of human impact and climate-driven distribution changes on the extinctions of these large mammals in a continuous temporal-spatial dimension. Here, our analyses showed that temperature change had significant effects on mammoth (genus Mammuthus ), rhinoceros (Rhinocerotidae), horse (Equidae) and deer (Cervidae). Rapid global warming was the predominant factor driving the total extinction of mammoths and rhinos in frigid zones from the Late Pleistocene and Early Holocene. Humans showed significant, negative effects on extirpations of the four mammalian taxa, and were the predominant factor causing the extinction or major extirpations of rhinos and horses. Deer survived both rapid climate warming and extensive human impacts. Our study indicates that both the current rates of warming and range shifts of species are much faster than those from the Late Pleistocene to Holocene. Our results provide new insight into the extinction of Late Quaternary megafauna by demonstrating taxon-, period- and region-specific differences in extinction drivers of climate change and human disturbances, and some implications about the extinction risk of animals by recent and ongoing climate warming. © 2017 The Author(s).

Generation of long subharmonic internal waves by surface waves

NASA Astrophysics Data System (ADS)

Tahvildari, Navid; Kaihatu, James M.; Saric, William S.

2016-10-01

A new set of Boussinesq equations is derived to study the nonlinear interactions between long waves in a two-layer fluid. The fluid layers are assumed to be homogeneous, inviscid, incompressible, and immiscible. Based on the Boussinesq equations, an analytical model is developed using a second-order perturbation theory and applied to examine the transient evolution of a resonant triad composed of a surface wave and two oblique subharmonic internal waves. Wave damping due to weak viscosity in both layers is considered. The Boussinesq equations and the analytical model are verified. In contrast to previous studies which focus on short internal waves, we examine long waves and investigate some previously unexplored characteristics of this class of triad interaction. In viscous fluids, surface wave amplitudes must be larger than a threshold to overcome viscous damping and trigger internal waves. The dependency of this critical amplitude as well as the growth and damping rates of internal waves on important parameters in a two-fluid system, namely the directional angle of the internal waves, depth, density, and viscosity ratio of the fluid layers, and surface wave amplitude and frequency is investigated.

Lyotropic chromonic liquid crystals as materials for optical and biosensing applications

NASA Astrophysics Data System (ADS)

Tortora, L.; Park, H.-S.; Antion, K.; Finotello, D.; Lavrentovich, O. D.

2007-02-01

Lyotropic chromonic liquid crystals (LCLCs) are formed by molecules with rigid polyaromatic cores and ionic groups at the periphery that form aggregates while in water. Most of the LCLCs are not toxic to the biological cells and can be used as an amplifying medium in real-time biosensors. The detector is based on the principle that the immune aggregates growing in the LCLC bulk trigger the director distortions. Self-assembly of LCLC molecules into oriented structures allows one to use them in various structured films. For example, layer-by-layer electrostatic deposition produces monomolecular layers and stacks of layers of LCLC with long-range in-plane orientational order which sets them apart from the standard Langmuir-Blodgett films. We demonstrate that divalent and multivalent salts as well as acidic and basic materials that alter pH of the LCLC water solutions, are drastically modifying the phase diagrams of LCLC, from shifting the phase transition temperatures by tens of degrees, to causing condensation of the LCLC aggregates into more compact structures, such as birefringent bundles or formation of a columnar hexagonal phase from the nematic phase.

Piecewise Potential Vorticity Inversion for Intense Extratropical Cyclones

NASA Astrophysics Data System (ADS)

Seiler, C.; Zwiers, F. W.

2017-12-01

Global climate models (GCMs) tend to simulate too few intense extratropical cyclones (ETCs) in the Northern Hemisphere (NH) under historic climate conditions. This bias may arise from the interactions of multiple drivers, including surface temperature gradients, latent heating in the lower troposphere, and the upper-level jet stream. Previous attempts to quantify the importance of these drivers include idealized model experiments or statistical approaches. The first method however cannot easily be implemented for a multi-GCM ensemble, and the second approach does not disentangle the interactions among drivers, nor does it prove causality. An alternative method that overcomes these limitations is piecewise potential vorticity inversion (PPVI). PPVI derives the wind and geopotential height fields by inverting potential vorticity (PV) for discrete atmospheric levels. Despite being a powerful diagnostic tool, PPVI has primarily been used to study the dynamics of individual events only. This study presents the first PPVI climatology for the 5% most intense NH ETCs that occurred from 1980 to 2016. Conducting PPVI to 3273 ETC tracks identified in ERA-Interim reanalysis, we quantified the contributions from 3 atmospheric layers to ETC intensity. The respective layers are the surface (1000 hPa), a lower atmospheric level (700-850 hPa) and an upper atmospheric level (100-500 hPa) that are associated with the contributions from surface temperature gradients, latent heating, and the jet stream, respectively. Results show that contributions are dominated by the lower level (40%), followed by the upper level (20%) and the surface (17%), while the remaining 23% are associated with the background flow. Contributions from the surface and the lower level are stronger in the western ocean basins owed to the presence of the warm ocean currents, while contributions from the upper level are stronger in the eastern basins. Vertical cross sections of ETC-centered composites show an undulation of the dynamic tropopause and the formation of a PV tower with values exceeding 1 PV unit during maximum ETC intensity. The dominant contribution from the lower level underlines the importance of latent heating for intense ETCs. The ability of GCMs to reproduce this mechanism remains to be assessed.

Reconstructing Historical Changes in Watersheds from Environmental Records: An Information Theory Approach

NASA Astrophysics Data System (ADS)

Guerrero, F. J.; Hatten, J. A.; Ruddell, B.; Penaranda, V.; Murillo, P.

2015-12-01

A 20% of the world's population is living in watersheds that suffer from water shortage. This situation has complex causes associated with historical changes in watersheds. However, disentangling the role of key drivers of water availability like climate change or land use practices is challenging. Part of the difficulty resides in that historical analysis is basically a process of empirical reconstruction from available environmental records (e.g. sediment cores or long-term hydrologic time series). We developed a mathematical approach, based on information theory, for historical reconstructions in watersheds. We analyze spectral entropies calculated directly or indirectly for sediment cores or long-term hydrologic time series respectively. Spectral entropy measures changes in Shannon's information of natural patterns (e.g. particle size distributions in lake bottoms or streamflow regimes) as they respond to different drivers. We illustrate the application of our approach with two case studies: a reconstruction of a time series of historical changes from a sediment core, and the detection of hydrologic alterations in watersheds associated to climate and forestry activities. In the first case we calculated spectral entropies from 700 sediment layers encompassing 1500 years of history in Loon Lake (Southern Oregon). In the second case, we calculated annual spectral entropies from daily discharge for the last 45 years in two experimental watersheds in the H. J. Andrews LTER site (Oregon Cascades). In Loon Lake our approach separated, without supervision, earthquakes from landslides and floods. It can also help to improve age models for sedimentary layers. At H. J. Andrews's sites our approach was able to identify hydrological alterations following a complete clear cut in 1975. It is also helpful to identify potential long-term impacts of these forestry activities, enhanced by climate change. Our results suggest that spectral entropy is central for translating between historical structural changes in natural patterns, and their timing and relevance in watershed history. Therefore, a more robust reconstruction of watershed history and a better identification of drivers for pressing environmental issues, seems possible under the framework of Shannon's information theory.

Meteorological variables to aid forecasting deep slab avalanches on persistent weak layers

USGS Publications Warehouse

Marienthal, Alex; Hendrikx, Jordy; Birkeland, Karl; Irvine, Kathryn M.

2015-01-01

Deep slab avalanches are particularly challenging to forecast. These avalanches are difficult to trigger, yet when they release they tend to propagate far and can result in large and destructive avalanches. We utilized a 44-year record of avalanche control and meteorological data from Bridger Bowl ski area in southwest Montana to test the usefulness of meteorological variables for predicting seasons and days with deep slab avalanches. We defined deep slab avalanches as those that failed on persistent weak layers deeper than 0.9 m, and that occurred after February 1st. Previous studies often used meteorological variables from days prior to avalanches, but we also considered meteorological variables over the early months of the season. We used classification trees and random forests for our analyses. Our results showed seasons with either dry or wet deep slabs on persistent weak layers typically had less precipitation from November through January than seasons without deep slabs on persistent weak layers. Days with deep slab avalanches on persistent weak layers often had warmer minimum 24-hour air temperatures, and more precipitation over the prior seven days, than days without deep slabs on persistent weak layers. Days with deep wet slab avalanches on persistent weak layers were typically preceded by three days of above freezing air temperatures. Seasonal and daily meteorological variables were found useful to aid forecasting dry and wet deep slab avalanches on persistent weak layers, and should be used in combination with continuous observation of the snowpack and avalanche activity.

Sprites, elf transients, and positive ground strokes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boccippio, D.J.; Boldi, R.; Williams, E.R.

1995-08-25

In two summertime mesoscale convective systems (MCSs), mesospheric optical sprite phenomena were often coincident with both large-amplitude positive cloud-to-ground lightning and transient Schumann resonance excitations of the entire Earth-ionosphere cavity. These observations, together with earlier studies of MCS electrification, suggest that sprites are triggered when the rapid removal of large quantities of positive charge from an areally extensive charge layer stresses the mesosphere to dielectric breakdown. 46 refs., 7 figs., 1 tab.

The Photospheric Footprints of Coronal Hole Jets

NASA Astrophysics Data System (ADS)

Muglach, Karin

2016-10-01

Coronal jets are transient, collimated ejections of plasma that are a common feature of solar X-ray and EUV image sequences. Of special interest are jets in coronal holes due to their possible contribution to the solar wind outflow. From a sample of 35 jet events I will investigate the photospheric signatures at the footpoints of these jets. White light images from the HMI on board SDO are used to derive the plane-of-sky flow field using local correlation tracking, and HMI magnetograms show the development of the magnetic flux. Both the evolution of the magnetic field and flows allow one to study the photospheric driver of these jets. One particularly interesting example demonstrates that the untwisting jet involves a tiny filament whose eruption is most likely triggered by the emergence of a small magnetic bipole close to one of its legs.

Very early warning of next El Niño.

PubMed

Ludescher, Josef; Gozolchiani, Avi; Bogachev, Mikhail I; Bunde, Armin; Havlin, Shlomo; Schellnhuber, Hans Joachim

2014-02-11

The most important driver of climate variability is the El Niño Southern Oscillation, which can trigger disasters in various parts of the globe. Despite its importance, conventional forecasting is still limited to 6 mo ahead. Recently, we developed an approach based on network analysis, which allows projection of an El Niño event about 1 y ahead. Here we show that our method correctly predicted the absence of El Niño events in 2012 and 2013 and now announce that our approach indicated (in September 2013 already) the return of El Niño in late 2014 with a 3-in-4 likelihood. We also discuss the relevance of the next El Niño to the question of global warming and the present hiatus in the global mean surface temperature.

High pulse rate high resolution optical radar system

NASA Technical Reports Server (NTRS)

Goss, W. C.; Burns, R. H.; Chi, K. (Inventor)

1973-01-01

The system is composed of an optical cavity with a laser and a mode locking means to build up an optical pulse. An optical switch is also provided within the cavity to convert the polarization of the optical pulse generated within the cavity. The optical switch comprises an electro-optical crystal driven by a time delayed driver circuit which is triggered by a coincident signal made from an optical pulse signal and a gating pulse signal. The converted optical pulse strikes a polarization sensitive prism and is deflected out of the cavity toward the pending target in the form of a pulse containing most of the optical energy generated by the laser in the pulse build-up period. After striking the target, the reflected energy is picked up by a transceiver with the total travel time of the pulse being recorded.

Seismically-triggered soft-sediment deformation structures close to a major strike-slip fault system in the Eastern Alps (Hirlatz cave, Austria)

NASA Astrophysics Data System (ADS)

Salomon, Martina Lan; Grasemann, Bernhard; Plan, Lukas; Gier, Susanne; Schöpfer, Martin P. J.

2018-05-01

We investigate episodic soft-sediment deformation structures cross-cut by normal faults preserved in unlithified finely laminated calcite rich sediments in the Hirlatz cave in the Northern Calcareous Alps (Austria). These sediments comprise varve-like alternations of brighter carbonate/quartz rich layers, and darker clay mineral rich layers. The deformed sediments contain abundant millimeter to centimeter-scale soft-sediment structures (load casts, ball-and-pillow structures), sheet slumps (thrust faults and folds), erosive channels filled with slides and chaotic slumps. After deposition and soft-sediment deformation normal faults developed within the entire sedimentary succession, an event that probably correlates with an offset of c. 10 cm of the passage wall above the outcrop. Our major conclusions are: (i) The sediments have a glacial origin and were deposited in the Hirlatz cave under phreatic fluvio-lacustrine conditions. The deposition and the soft-sediment deformation occurred most likely during the last glaciation (i.e. around 25 ka ago); (ii) The liquefaction and formation of the soft-sediment structures in water-saturated stratified layers was triggered by episodic seismic events; (iii) The internally deformed sediments were later displaced by normal faults; (iv) A possible source for the seismic events is the active sinistral Salzach-Ennstal-Mariazeller-Puchberger (SEMP) strike-slip fault which is located about 10 km south of the outcrop and plays a major role in accommodating the extrusion of the Eastern Alps towards the Pannonian Basin. To our knowledge, the described structures are the first report of liquefaction and seismically induced soft-sediment deformations in Quaternary sediments in the Eastern Alps.

Aberrant c-erbB2 expression in cell clusters overlying focally disrupted breast myoepithelial cell layers: a trigger or sign for emergence of more aggressive cell clones?

PubMed Central

Zhang, Xichen; Hashemi, Shahreyar Shar; Yousefi, Morvarid; Ni, Jinsong; Wang, Qiuyue; Gao, Ling; Gong, Pengtao; Gao, Chunling; Sheng, Joy; Mason, Jeffrey; Man, Yan-gao

2008-01-01

Our recent studies revealed that cell clusters overlying focal myoepithelial cell layer disruption (FMCLD) had a significantly higher frequency of genetic instabilities and expression of invasion-related genes than their adjacent counterparts within the same duct. Our current study attempted to assess whether these cell clusters would also have elevated c-erbB2 expression. Human breast tumors (n=50) with a high frequency of FMCLD were analyzed with double immunohistochemistry, real-time RT-PCR, and chromogenic in situ hybridization for c-erbB2 protein and gene expression. Of 448 FMCLD detected, 404 (90.2%) were associated with cell clusters that had intense c-erbB2 immunoreactivities primarily in their cytoplasm, in contrast to their adjacent counterparts within the same duct, which had no or barely detectable c-erbB2 expression. These c-erbB2 positive cells were arranged as tongue-like projections, “puncturing” into the stroma, and about 20% of them were in direct continuity with tube-like structures that resembled blood vessels. Aberrant c-erbB2 expression was also seen in clusters of architecturally normal-appearing ducts that had distinct cytological abnormalities in both ME and epithelial cells, whereas not in their clear-cut normal counterparts. Molecular assays detected markedly higher c-erbB2 mRNA and gene amplification in cell clusters associated with FMCLD than in those associated with non-disrupted ME cell layers. Our findings suggest that cell clusters overlying FMCLD may represent the precursors of pending invasive lesions, and that aberrant cerbB2 expression may trigger or signify the emergence of biologically more aggressive cell clones. PMID:18726004

Specifically Formed Corona on Silica Nanoparticles Enhances Transforming Growth Factor β1 Activity in Triggering Lung Fibrosis.

PubMed

Wang, Zhenzhen; Wang, Chunming; Liu, Shang; He, Wei; Wang, Lintao; Gan, JingJing; Huang, Zhen; Wang, Zhenheng; Wei, Haoyang; Zhang, Junfeng; Dong, Lei

2017-02-28

A corona is a layer of macromolecules formed on a nanoparticle surface in vivo. It can substantially change the biological identity of nanomaterials and possibly trigger adverse responses from the body tissues. Dissecting the role of the corona in the development of a particular disease may provide profound insights for understanding toxicity of nanomaterials in general. In our present study, we explored the capability of different silica nanoparticles (SiNPs) to induce silicosis in the mouse lung and analyzed the composition of coronas formed on these particles. We found that SiNPs of certain size and surface chemistry could specifically recruit transforming growth factor β1 (TGF-β1) into their corona, which subsequently induces the development of lung fibrosis. Once embedded into the corona on SiNPs, TGF-β1 was remarkably more stable than in its free form, and its fibrosis-triggering activity was significantly prolonged. Our study meaningfully demonstrates that a specific corona component on a certain nanoparticle could initiate a particular pathogenic process in a clinically relevant disease model. Our findings may shed light on the understanding of molecular mechanisms of human health risks correlated with exposure to small-scale substances.

Triggers and Manifestations of Flare Energy Release in the Low Atmosphere

NASA Astrophysics Data System (ADS)

Kosovichev, A. G.; Sharykin, I. N.; Sadykov, V. M.; Vargas, S.; Zimovets, I. V.

2016-12-01

The main goal is to understand triggers and manifestations of the flare energy release in the lower layers of the solar atmosphere (the photosphere and chromosphere) using high-resolution optical observations and magnetic field measurements. As a case study we present results for an M-class flare. We analyze optical images, HMI Dopplergrams and vector magnetograms, and use Non-Linear Force-Free Field (NLFFF) extrapolation for reconstruction of the magnetic topology. The NLFFF modelling reveals interaction of oppositely directed magnetic flux-tubes in the Polarity Inversion Line (PIL). These two interacting magnetic flux tubes are observed as a compact sheared arcade along the PIL in the high-resolution broad-band continuum images from New Solar Telescope (NST). In the vicinity of the PIL, the NST H-alpha observations reveal formation of a thin three-ribbon structure corresponding to the small-scale photospheric magnetic arcade. Magnetic reconnection is triggered by two interacting magnetic flux tubes with forming current sheet extended along the PIL. Presented observational results evidence in favor of location of the primary energy release site in the dense chromosphere where plasma is partially ionized in the region of strong electric currents concentrated near the polarity inversion line.

Specific Barriers and Drivers in Different Stages of Decision-Making about Energy Efficiency Upgrades in Private Homes

PubMed Central

Klöckner, Christian A.; Nayum, Alim

2016-01-01

Energy efficiency upgrades of privately owned homes like adding to the insulation layers in the walls, roof or floor, or replacing windows with more efficiently insulated versions can contribute significantly to reducing the energy impact of the building sector and thus also the CO2 footprint of a household. However, even in countries like Norway that have a rather high rate of renovation, energy upgrades are not always integrated into such a refurbishment project. This study tests which structural and internal psychological barriers hinder and which drivers foster decision-making to implement such measures, once a renovation project is planned. With a theoretical background in stage-based models of decision-making 24 barriers and drivers were tested for their specific effect in the stages of decision-making. The four stages of decision-making assumed in this study were (1) “not being in a decision mode,” (2) “deciding what to do,” (3) “deciding how to do it,” and (4) “planning implementation.” Based on an online survey of 3787 Norwegian households, it was found that the most important barriers toward deciding to implement energy efficiency upgrades were not owning the dwelling and feeling the right time had not come yet. The most important drivers of starting to decide were higher expected comfort levels, better expected living conditions, and an expected reduction of energy costs. For the transition from deciding what to do to how to do it, not managing to make a decision and feeling the right point in time has not come yet were the strongest barriers, easily accessible information and an expected reduction of energy costs were the most important drivers. The final transition from deciding how to do the upgrades to planning implementation was driven by expecting a payoff within a reasonable time frame and higher expected comfort levels; the most important barriers were time demands for supervising contractors and—again—a feeling that the right point in time has not come yet. Implications for policy-making and marketing are discussed. PMID:27660618

Specific Barriers and Drivers in Different Stages of Decision-Making about Energy Efficiency Upgrades in Private Homes.

PubMed

Klöckner, Christian A; Nayum, Alim

2016-01-01

Energy efficiency upgrades of privately owned homes like adding to the insulation layers in the walls, roof or floor, or replacing windows with more efficiently insulated versions can contribute significantly to reducing the energy impact of the building sector and thus also the CO2 footprint of a household. However, even in countries like Norway that have a rather high rate of renovation, energy upgrades are not always integrated into such a refurbishment project. This study tests which structural and internal psychological barriers hinder and which drivers foster decision-making to implement such measures, once a renovation project is planned. With a theoretical background in stage-based models of decision-making 24 barriers and drivers were tested for their specific effect in the stages of decision-making. The four stages of decision-making assumed in this study were (1) "not being in a decision mode," (2) "deciding what to do," (3) "deciding how to do it," and (4) "planning implementation." Based on an online survey of 3787 Norwegian households, it was found that the most important barriers toward deciding to implement energy efficiency upgrades were not owning the dwelling and feeling the right time had not come yet. The most important drivers of starting to decide were higher expected comfort levels, better expected living conditions, and an expected reduction of energy costs. For the transition from deciding what to do to how to do it, not managing to make a decision and feeling the right point in time has not come yet were the strongest barriers, easily accessible information and an expected reduction of energy costs were the most important drivers. The final transition from deciding how to do the upgrades to planning implementation was driven by expecting a payoff within a reasonable time frame and higher expected comfort levels; the most important barriers were time demands for supervising contractors and-again-a feeling that the right point in time has not come yet. Implications for policy-making and marketing are discussed.

Functional Basis for Efficient Physical Layer Classical Control in Quantum Processors

NASA Astrophysics Data System (ADS)

Ball, Harrison; Nguyen, Trung; Leong, Philip H. W.; Biercuk, Michael J.

2016-12-01

The rapid progress seen in the development of quantum-coherent devices for information processing has motivated serious consideration of quantum computer architecture and organization. One topic which remains open for investigation and optimization relates to the design of the classical-quantum interface, where control operations on individual qubits are applied according to higher-level algorithms; accommodating competing demands on performance and scalability remains a major outstanding challenge. In this work, we present a resource-efficient, scalable framework for the implementation of embedded physical layer classical controllers for quantum-information systems. Design drivers and key functionalities are introduced, leading to the selection of Walsh functions as an effective functional basis for both programing and controller hardware implementation. This approach leverages the simplicity of real-time Walsh-function generation in classical digital hardware, and the fact that a wide variety of physical layer controls, such as dynamic error suppression, are known to fall within the Walsh family. We experimentally implement a real-time field-programmable-gate-array-based Walsh controller producing Walsh timing signals and Walsh-synthesized analog waveforms appropriate for critical tasks in error-resistant quantum control and noise characterization. These demonstrations represent the first step towards a unified framework for the realization of physical layer controls compatible with large-scale quantum-information processing.

Determination of monomethylmercury and dimethylmercury in the Arctic marine boundary layer.

PubMed

Baya, Pascale A; Gosselin, Michel; Lehnherr, Igor; St Louis, Vincent L; Hintelmann, Holger

2015-01-06

Our understanding of the biogeochemical cycling of monomethylmercury (MMHg) in the Arctic is incomplete because atmospheric sources and sinks of MMHg are still unclear. We sampled air in the Canadian Arctic marine boundary layer to quantify, for the first time, atmospheric concentrations of methylated Hg species (both MMHg and dimethylmercury (DMHg)), and, estimate the importance of atmospheric deposition as a source of MMHg to Arctic land- and sea-scapes. Overall atmospheric MMHg and DMHg concentrations (mean ± SD) were 2.9 ± 3.6 and 3.8 ± 3.1 (n = 37) pg m(-3), respectively. Concentrations of methylated Hg species in the marine boundary layer varied significantly among our sites, with a predominance of MMHg over Hudson Bay (HB), and DMHg over Canadian Arctic Archipelago (CAA) waters. We concluded that DMHg is of marine origin and that primary production rate and sea-ice cover are major drivers of its concentration in the Canadian Arctic marine boundary layer. Summer wet deposition rates of atmospheric MMHg, likely to be the product of DMHg degradation in the atmosphere, were estimated at 188 ± 117.5 ng m(-2) and 37 ± 21.7 ng m(-2) for HB and CAA, respectively, sustaining MMHg concentrations available for biomagnification in the pelagic food web.

Relationship between PC index and magnetospheric field-aligned currents measured by Swarm satellites

NASA Astrophysics Data System (ADS)

Troshichev, O.; Sormakov, D.; Behlke, R.

2018-03-01

The relationship between the magnetospheric field-aligned currents (FAC) monitored by the Swarm satellites and the magnetic activity PC index (which is a proxy of the solar wind energy incoming into the magnetosphere) is examined. It is shown that current intensities measured in the R1 and R2 FAC layers at the poleward and equtorward boundaries of the auroral oval are well correlated, the R2 currents being evidently secondary in relation to R1 currents and correlation in the dawn and dusk oval sectors being better than in the noon and night sectors. There is evident relationship between the PC index and the intensity of field-aligned currents in the R1 dawn and dusk layers: increase of FAC intensity in the course of substorm development is accompanied by increasing the PC index values. Correlation between PC and FAC intensities in the R2 dawn and dusk layers is also observed, but it is much weaker. No correlation is observed between PC and field-aligned currents in the midnight as well as in the noon sectors ahead of the substorm expansion phase. The results are indicative of the R1 field-aligned currents as a driver of the polar cap magnetic activity (PC index) and currents in the R2 layer.

Moisture Content Numerical Simulation on Structural Damage of Hot Mix Asphaltic Pavement

NASA Astrophysics Data System (ADS)

Abejide, O. S.; Mostafa, M. M. H.

2017-06-01

Considering the merits of road transportation in the economy and communication activities of the modern societies, it is imperative to design a safe, stable, efficient and cost effective road that will lead to increased economic development and growth of the South African nation. Although, the overarching effect of failed roads has in many ways led to increased travel time, loss of life and property; leading to reduced driver control on failed road sections (riding quality). Thus, time rate delamination of flexible pavement is a major focus of this study. Since structural collapse in a flexible pavement structure is caused by the evolution of different types of damage mechanisms; fatigue cracking, advanced crushing, temperature variation, and delamination. The effect of moisture content on HMA was analysed. The analysis from the multi-layered elastic model indicates that increase in moisture content in the underlying layer of HMA pavement results to increase in the strain of the individual layers and culminates to a decrease in the structural carrying capacity of the pavement with respect to number of load cycles that can be carried on the HMA pavement. This study shows a clear relationship between the moisture/saturation coefficient and the Elastic Modulus of the underlying geometric material layer properties of the pavement during the service life of the pavement.

Deleterious localized stress fields: the effects of boundaries and stiffness tailoring in anisotropic laminated plates

PubMed Central

Weaver, P. M.

2016-01-01

The safe design of primary load-bearing structures requires accurate prediction of stresses, especially in the vicinity of geometric discontinuities where deleterious three-dimensional stress fields can be induced. Even for thin-walled structures significant through-thickness stresses arise at edges and boundaries, and this is especially precarious for laminates of advanced fibre-reinforced composites because through-thickness stresses are the predominant drivers in delamination failure. Here, we use a higher-order equivalent single-layer model derived from the Hellinger–Reissner mixed variational principle to examine boundary layer effects in laminated plates comprising constant-stiffness and variable-stiffness laminae and deforming statically in cylindrical bending. The results show that zigzag deformations, which arise due to layerwise differences in the transverse shear moduli, drive boundary layers towards clamped edges and are therefore critically important in quantifying localized stress gradients. The relative significance of the boundary layer scales with the degree of layerwise anisotropy and the thickness to characteristic length ratio. Finally, we demonstrate that the phenomenon of alternating positive and negative transverse shearing deformation through the thickness of composite laminates, previously only observed at clamped boundaries, can also occur at other locations as a result of smoothly varying the material properties over the in-plane dimensions of the laminate. PMID:27843401

Microbial community diversity of the eastern Atlantic Ocean reveals geographic differences

NASA Astrophysics Data System (ADS)

Friedline, C. J.; Franklin, R. B.; McCallister, S. L.; Rivera, M. C.

2012-01-01

Prokaryotic communities are recognized as major drivers of the biogeochemical processes in the oceans. However, the genetic diversity and composition of those communities is poorly understood. The aim of this study was to investigate the eubacterial communities in three different water layers: surface (2-20 m), deep chlorophyll maximum (DCM; 28-90 m), and deep (100-4600 m) at nine stations along the eastern Atlantic Ocean from 42.8° N to 23.7° S. In order to describe the dynamics of the eubacterial assemblages in relation to depth, associated environmental properties, and Longhurstian ecological provinces community DNA was extracted from 16 samples, from which the V6 region of 16s rDNA was PCR-amplified with eubacteria-specific primers, and the PCR amplicons were pyrosequenced. A total of 352 029 sequences were generated; after quality filtering and processing, 257 260 sequences were clustered into 2871 normalized Operational Taxonomic Units (OTU) using a definition of 97% sequence identity. Comparisons of the phylogenetic affiliation of those 2871 OTUs show more than 54% of them were assigned to the Proteobacteria, with the Alphaproteobacteria representing 4% of the total Proteobacteria OTUs, and the Gammaproteobacteria representing 22%. Within the Alphaproteobacteria-affiliated OTUs, 44% of the OTUs were associated with the ubiquitous SAR11 clade. The phylum Cyanobacteria represent 10% of the reads, with the majority of those reads among the GpIIa family including Prochlorococcus and Synechococcus. Among the Gammaproteobacteria, a single OTU affiliated to Alteromonas comprises ~3% of the abundance. The phyla Bacteroidetes, Verrucomicrobia, Actinobacteria, and Firmicutes represent approximately 7%, 0.8%, 2%, and 0.05% of the read abundance, respectively. Community ecology statistical analyses and a novel implementation of Bayesian inference suggests that eastern Atlantic Ocean eubacterial assemblages are vertically stratified and associated with water layers characterized by unique environmental signals (e.g., temperature, salinity, and nutrients). Genetic composition of eubacterial communities from the same water layer are more similar to each other than to the communities from different water layers. Moreover, within the same water layer the separation of the communities appears to show a significant distance effect. Surface eubacterial communities displayed a general congruency with the ecological provinces defined by Longhurst with exceptions usually associated with unique hydrographic and biogeochemical features. Collectively, our findings suggest that a vertical and latitudinal biogeographical signature is present in the studied communities and that both environmental parameters and ecological provinces are drivers of eubacterial assemblages in the eastern Atlantic Ocean.

Evidence of organized intraseasonal convection linked to ocean dynamics in the Seychelles-Chagos thermocline ridge

NASA Astrophysics Data System (ADS)

D'Addezio, Joseph M.; Subrahmanyam, Bulusu

2018-01-01

The Madden-Julian oscillation (MJO) is the dominant driver of intraseasonal variability across the equatorial domain of the global ocean with alternating wet and dry bands that propagate eastward primarily between 5°N and 5°S. Past research has shown that MJOs impact the surface and subsurface variability of the Seychelles-Chagos thermocline ridge (SCTR) (55°E-65°E, 5°S-12°S) located in the southwest tropical Indian Ocean (SWTIO), but investigations of how SWTIO internal dynamics may play an important role in producing MJO events remain limited. This study uses Argo, in conjunction with several remote sensing and reanalysis products, to demonstrate that SWTIO oceanic dynamics, particularly barrier layer formation and near surface heat buildup, may be associated with MJO genesis between August and December of most years between 2005 and 2013. A total of eight SWTIO specific MJO events are observed, all occurring between August and December. Four of the eight events are correlated with positive SWTIO total heat content (THC) and barrier layer thickness (BLT) interannual anomalies. Two others formed over the SWTIO during times when only one of the variables was at or above their seasonal average, while two additional events occurred when both variables experienced negative interannual anomalies. Lacking complete 1:1 correlation between the hypothesized oceanic state and the identified SWTIO MJO events, we conclude that additional work is required to better understand when variability in key oceanic variables plays a primary role in regional MJO genesis or when other factors, such as atmospheric variability, are the dominate drivers.

The influence of tree species composition on the storage and mobility of semivolatile organic compounds in forest soils.

PubMed

Komprdová, Klára; Komprda, Jiří; Menšík, Ladislav; Vaňková, Lenka; Kulhavý, Jiří; Nizzetto, Luca

2016-05-15

Soil contamination with PCBs and PAHs in adjacent forest plots, characterized by a distinct composition in tree species (spruce only, mixed and beech only), was analyzed to investigate the influence of ecosystem type on contaminant mobility in soil under very similar climate and exposure conditions. Physical-chemical properties and contaminant concentrations in litter (L), organic (F, H) and mineral (A, B) soil horizons were analyzed. Contaminant distribution in the soil core varied both in relation to forest type and contaminant group/properties. Contaminant mobility in soil was assessed by examining the ratios of total organic carbon (TOC)-standardized concentrations across soil horizons (Enrichment factors, EFTOC) and the relationship between EFTOC and the octanol-water equilibrium partitioning coefficient (KOW). Contaminant distribution appeared to be highly unsteady, with pedogenic/biogeochemical drivers controlling contaminant mobility in organic layers and leaching controlling accumulation in mineral layers. Lighter PCBs displayed higher mobility in all forest types primarily controlled by leaching and, to a minor extent, diffusion. Pedogenic processes controlling the formation of soil horizons were found to be crucial drivers of PAHs and heavier PCBs distribution. All contaminants appeared to be more mobile in the soil of the broadleaved plot, followed by mixed canopy and spruce forest. Increasing proportion of deciduous broadleaf species in the forest can thus lead to faster degradation or the faster leaching of PAHs and PCBs. The composition of humic substances was found to be a better descriptor of contaminant concentration than TOC. Copyright © 2016 Elsevier B.V. All rights reserved.

Drivers of tall shrub proliferation adjacent to the Dempster Highway, Northwest Territories, Canada

NASA Astrophysics Data System (ADS)

Cameron, Emily A.; Lantz, Trevor C.

2016-04-01

Arctic ecosystems are undergoing rapid changes as a result of climate warming and more frequent disturbances. Disturbances can have particularly large effects on high-latitude ecosystems when ecosystem structure and function is controlled by strong feedbacks between soil conditions, vegetation, and ground thermal regime. In this study we investigated the impact of road construction and maintenance on vegetation structure and biomass along the Dempster Highway where it crosses the Peel Plateau in the Northwest Territories. To explore drivers of tall shrub proliferation and to quantify shrub proliferation in this region of continuous permafrost, greyscale air photos (1975) and Quickbird satellite imagery (2008) were used to map landcover change within two 0.6 km2 belts next to the road and two 0.6 km2 belts 500 m away from the road. Maps showing areas where: 1) tall shrubs expanded, and 2) dwarf shrub tundra resisted invasion were then used to select field sites where a suite of biophysical variables were measured. Rapid tall shrub proliferation and greater biomass adjacent to the road indicate that disturbance can facilitate vegetation change in tundra environments. Our field data also suggests that increased shrub proliferation adjacent to the road was caused by greater soil moisture. Tall shrub proliferation adjacent to the road occurred at lower elevation sites characterized by wetter soils with thicker organic layers. Areas that resisted tall shrub encroachment were located at higher elevations and had drier soils with thin organic layers. Our observations also support previous work illustrating that tall shrub expansion next to the highway promotes strong positive feedbacks to ongoing shrub growth and proliferation.

Fire timing in relation to masting: an important determinant of post-fire recruitment success for the obligate-seeding arid zone soft spinifex (Triodia pungens).

PubMed

Wright, Boyd R; Fensham, Roderick J

2018-01-25

Plant species with fire-triggered germination are common in many fire-prone ecosystems. For such plants, fire timing in relation to the timing of reproduction may strongly influence post-fire population regeneration if: (a) flowering occurs infrequently (e.g. plants are mast seeders); and (b) seed survival rates are low and input from the current year's flowering therefore contributes a large proportion of the viable dormant seedbank. The role of fire timing in relation to masting as a driver of post-fire recruitment has rarely been examined directly, so this study tested the hypothesis that fires shortly after masting trigger increased recruitment of the obligate-seeding arid zone spinifex, Triodia pungens R. Br., an iteroparous masting grass with smoke-cued germination. Phenological monitoring of T. pungens was conducted over 5 years, while a longitudinal seedbank study assessed the influence of seeding events on soil-stored seedbank dynamics. Concurrently, a fire experiment with randomized blocking was undertaken to test whether T. pungens hummocks burnt shortly after masting have greater post-fire recruitment than hummocks burnt when there has not been recent input of seeds. Triodia pungens flowered in all years, though most flowerings were characterized by high rates of flower abortion. A mast flowering with high seed set in 2012 triggered approx. 200-fold increases in seedbank densities, and seedbank densities remained elevated for 24 months after this event. The fire experiment showed significantly higher recruitment around hummocks burnt 6 months after the 2012 mast event than around hummocks that were burnt but prevented from masting by having inflorescences clipped. Fires shortly after masting trigger mass recruitment in T. pungens because such fires synchronize an appropriate germination cue (smoke) with periods when seedbank densities are elevated. Interactions between natural fire regimes, seedbank dynamics and fire management prescriptions must be considered carefully when managing fire-sensitive masting plants such as T. pungens. © The Author(s) 2017. Published by Oxford University Press on behalf of the Annals of Botany Company. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Investigate moped-car conflicts in China using a naturalistic driving study approach.

PubMed

Glaser, Yi G; Guo, Feng; Fang, Youjia; Deng, Bing; Hankey, Jonathan

2017-12-01

Mopeds are a popular transportation mode in Europe and Asia. Moped-related traffic accidents account for a large proportion of crash fatalities. To develop moped-related crash countermeasures, it is important to understand the characteristics of moped-related conflicts. Naturalistic driving study data were collected in Shanghai, China from 36 car drivers. The data included 2,878h and 78,296km driven from 13,149 trips. Moped-car conflicts were identified and examined from the passenger car driver's perspective using kinematic trigger algorithms and manual video reduction. A total of 119 moped-car conflicts were identified, including 74 high g-force conflicts and 45 low g-force events. These conflicts were classified into 22 on-road configurations where both similarities and differences were found as compared to Western Countries. The majority of the conflicts occurred on secondary main roads and branch roads. Hard braking was the primary response that the car drivers made to these conflicts rather than hard steering. The identified on-road vehicle-moped conflict configurations in Shanghai, China may be attributed to the complicated traffic environment and risky behavior of moped riders. The lower prevalence of hard steering in Shanghai as compared to the United States may be due to the lower speeds at event onsets or less available steering space, e.g., less available shoulder area on Chinese urban roads. The characteristics of moped-car conflicts may impact the design of active safety countermeasures on passenger cars. The pilot data from Shanghai urban areas suggest that countermeasures developed for China may require some modifications to those developed for the United States and European countries, although this recommendation may not be conclusive given the small sample size of the study. Future studies with large samples may help better understand the characteristics of moped-car conflicts. Copyright © 2017 National Safety Council and Elsevier Ltd. All rights reserved.

Performance Evaluation of CMUT-Based Ultrasonic Transformers for Galvanic Isolation.

PubMed

Heller, Jacques; Boulme, Audren; Alquier, Daniel; Ngo, Sophie; Certon, Dominique

2018-04-01

This paper presents the development of a novel acoustic transformer with high galvanic isolation dedicated to power switch triggering. The transformer is based on two capacitive micromachined ultrasonic transducers layered on each side of a silicon substrate; one is the primary circuit, and the other is the secondary circuit. The thickness mode resonance of the substrate is leveraged to transmit the triggering signal. The fabrication and characterization of an initial prototype is presented in this paper. All experimental results are discussed, from the electrical impedance measurements to the power efficiency measurements, for different electrical load conditions. A comparison with a specifically developed finite-element method model is done. Simulations are finally used to identify the optimization rules of this initial prototype. It is shown that the power efficiency can be increased from 35% to 60%, and the transmitted power can be increased from 1.6 to 45 mW/Volt.

A vertical handoff decision algorithm based on ARMA prediction model

NASA Astrophysics Data System (ADS)

Li, Ru; Shen, Jiao; Chen, Jun; Liu, Qiuhuan

2012-01-01

With the development of computer technology and the increasing demand for mobile communications, the next generation wireless networks will be composed of various wireless networks (e.g., WiMAX and WiFi). Vertical handoff is a key technology of next generation wireless networks. During the vertical handoff procedure, handoff decision is a crucial issue for an efficient mobility. Based on auto regression moving average (ARMA) prediction model, we propose a vertical handoff decision algorithm, which aims to improve the performance of vertical handoff and avoid unnecessary handoff. Based on the current received signal strength (RSS) and the previous RSS, the proposed approach adopt ARMA model to predict the next RSS. And then according to the predicted RSS to determine whether trigger the link layer triggering event and complete vertical handoff. The simulation results indicate that the proposed algorithm outperforms the RSS-based scheme with a threshold in the performance of handoff and the number of handoff.

Readiness of the ATLAS Trigger and Data Acquisition system for the first LHC beams

NASA Astrophysics Data System (ADS)

Vandelli, W.; Atlas Tdaq Collaboration

2009-12-01

The ATLAS Trigger and Data Acquisition (TDAQ) system is based on O(2k) processing nodes, interconnected by a multi-layer Gigabit network, and consists of a combination of custom electronics and commercial products. In its final configuration, O(20k) applications will provide the needed capabilities in terms of event selection, data flow, local storage and data monitoring. In preparation for the first LHC beams, many TDAQ sub-systems already reached the final configuration and roughly one third of the final processing power has been deployed. Therefore, the current system allows for a sensible evaluation of the performance and scaling properties. In this paper we introduce the ATLAS TDAQ system requirements and architecture and we discuss the status of software and hardware component. We moreover present the results of performance measurements validating the system design and providing a figure for the ATLAS data acquisition capabilities in the initial data taking period.

Fundamental Processes of Atomization in Fluid-Fluid Flows

NASA Technical Reports Server (NTRS)

McCready, M. J.; Chang, H.-C.; Leighton, D. T.

2001-01-01

This report outlines the major results of the grant "Fundamental Processes of Atomization in Fluid-Fluid Flows." These include: 1) the demonstration that atomization in liquid/liquid shear flow is driven by a viscous shear instability that triggers the formation of a long thin sheet; 2) discovery of a new mode of interfacial instability for oscillatory two-layer systems whereby a mode that originates within the less viscous liquid phase causes interfacial deformation as the oscillation proceeds; 3) the demonstration that rivulet formation from gravity front occurs because the local front shape specified by gravity and surface tension changes from a nose to a wedge geometry, thus triggering a large increase in viscous resistance; and 4) extension of the studies on nonlinear wave evolution on falling films and in stratified flow, particularly the evolution towards large-amplitude solitary waves that tend to generate drops.

Disease-related amyloidogenic variants of human lysozyme trigger the unfolded protein response and disturb eye development in Drosophila melanogaster.

PubMed

Kumita, Janet R; Helmfors, Linda; Williams, Jocy; Luheshi, Leila M; Menzer, Linda; Dumoulin, Mireille; Lomas, David A; Crowther, Damian C; Dobson, Christopher M; Brorsson, Ann-Christin

2012-01-01

We have created a Drosophila model of lysozyme amyloidosis to investigate the in vivo behavior of disease-associated variants. To achieve this objective, wild-type (WT) protein and the amyloidogenic variants F57I and D67H were expressed in Drosophila melanogaster using the UAS-gal4 system and both the ubiquitous and retinal expression drivers Act5C-gal4 and gmr-gal4. The nontransgenic w(1118) Drosophila line was used as a control throughout. We utilized ELISA experiments to probe lysozyme protein levels, scanning electron microscopy for eye phenotype classification, and immunohistochemistry to detect the unfolded protein response (UPR) activation. We observed that expressing the destabilized F57I and D67H lysozymes triggers UPR activation, resulting in degradation of these variants, whereas the WT lysozyme is secreted into the fly hemolymph. Indeed, the level of WT was up to 17 times more abundant than the variant proteins. In addition, the F57I variant gave rise to a significant disruption of the eye development, and this correlated to pronounced UPR activation. These results support the concept that the onset of familial amyloid disease is linked to an inability of the UPR to degrade completely the amyloidogenic lysozymes prior to secretion, resulting in secretion of these destabilized variants, thereby leading to deposition and associated organ damage.

Improving Robot Motor Learning with Negatively Valenced Reinforcement Signals

PubMed Central

Navarro-Guerrero, Nicolás; Lowe, Robert J.; Wermter, Stefan

2017-01-01

Both nociception and punishment signals have been used in robotics. However, the potential for using these negatively valenced types of reinforcement learning signals for robot learning has not been exploited in detail yet. Nociceptive signals are primarily used as triggers of preprogrammed action sequences. Punishment signals are typically disembodied, i.e., with no or little relation to the agent-intrinsic limitations, and they are often used to impose behavioral constraints. Here, we provide an alternative approach for nociceptive signals as drivers of learning rather than simple triggers of preprogrammed behavior. Explicitly, we use nociception to expand the state space while we use punishment as a negative reinforcement learning signal. We compare the performance—in terms of task error, the amount of perceived nociception, and length of learned action sequences—of different neural networks imbued with punishment-based reinforcement signals for inverse kinematic learning. We contrast the performance of a version of the neural network that receives nociceptive inputs to that without such a process. Furthermore, we provide evidence that nociception can improve learning—making the algorithm more robust against network initializations—as well as behavioral performance by reducing the task error, perceived nociception, and length of learned action sequences. Moreover, we provide evidence that punishment, at least as typically used within reinforcement learning applications, may be detrimental in all relevant metrics. PMID:28420976

Regional Landslide Hazard Assessment Considering Potential Climate Change

NASA Astrophysics Data System (ADS)

Almeida, S.; Holcombe, E.; Pianosi, F.; Wagener, T.

2016-12-01

Landslides have many negative economic and societal impacts, including the potential for significant loss of life and damage to infrastructure. These risks are likely to be exacerbated in the future by a combination of climatic and socio-economic factors. Climate change, for example, is expected to increase the occurrence of rainfall-triggered landslides, because a warmer atmosphere tends to produce more high intensity rainfall events. Prediction of future changes in rainfall, however, is subject to high levels of uncertainty, making it challenging for decision-makers to identify the areas and populations that are most vulnerable to landslide hazards. In this study, we demonstrate how a physically-based model - the Combined Hydrology and Stability Model (CHASM) - can be used together with Global Sensitivity Analysis (GSA) to explore the underlying factors controlling the spatial distribution of landslide risks across a regional landscape, while also accounting for deep uncertainty around potential future rainfall triggers. We demonstrate how GSA can be used to analyse CHASM which in turn represents the spatial variability of hillslope characteristics in the study region, while accounting for other uncertainties. Results are presented in the form of landslide hazard maps, utilising high-resolution digital elevation datasets for a case study in St Lucia in the Caribbean. Our findings about spatial landslide hazard drivers have important implications for data collection approaches and for long-term decision-making about land management practices.

Urothelium-adherent, ion-triggered liposome-in-gel system as a platform for intravesical drug delivery.

PubMed

GuhaSarkar, Shruti; More, Prachi; Banerjee, Rinti

2017-01-10

Instillations of therapeutic agents into the urinary bladder have limited efficacy due to drug washout and inadequate attachment to and penetration into the bladder wall. Instilled nanoparticles alone have low stability and high susceptibility to washout, while gel-based systems are difficult to administer and retain. To overcome disadvantages of current technologies, a biodegradable, in situ-gelling liposome-in-gel (LP-Gel) system was developed for instillation into the bladder, composed of nano-sized, fluidizing liposomes incorporated into a "smart" biopolymeric, urine-triggered hydrogel. The liposomes are optimized for their fluidizing composition in order to enhance cellular penetration through the urothelial barrier, while the hydrogel co-delivers the suspended nanocarriers and enhances adhesion on the mucin layer of the urothelium. The composite system thus mimics both the lipid membranes and mucosal layer that comprise the urothelial barrier. LP-Gel showed appreciable cytotoxicity in rat and human bladder cancer cells, and instillation into rat bladder showed enhanced adhesion on the urothelium and increased penetration into the bladder wall. Instillation of paclitaxel-loaded LP-Gel showed drug retention for at least 7days, substantially higher than free drug (few hours), and with negligible systemic levels. The LP-Gel platform system thus facilitates prolonged drug localization in the bladder, showing potential use in intravesical applications. Copyright © 2016. Published by Elsevier B.V.

Aerogeophysical evidence for active volcanism beneath the West Antarctic Ice Sheet

NASA Technical Reports Server (NTRS)

Blankenship, Donald D.; Bell, Robin E.; Hodge, Steven M.; Brozena, John M.; Behrendt, John C.

1993-01-01

Although it is widely understood that the collapse of the West Antarctic Ice Sheet (WAIS) would cause a global sea-level rise of 6 m, there continues to be considerable debate about the response of this ice sheet to climate change. The stability of the WAIS, which is characterized by a bed grounded well below sea level, may depend on geologically controlled conditions at the base, which are independent of climate. Ice streams moving up to 750 m/yr disperse material from the interior through to the oceans. As these ice streams tend to buffer the reservoir of slow-moving inland ice from exposure to oceanic degradation, understanding the ice-streaming process is important for evaluating WAIS stability. There is strong evidence that ice streams slide on a lubricating layer of water-saturated till. Development of this basal layer requires both water and easily eroded sediments. Active lithospheric extension may elevate regional heat flux, increase basal melting, and trigger ice streaming. If a geologically defined boundary with a sharp contrast in geothermal flux exists beneath the WAIS, ice streams may only be capable of operating as a buffer over a restricted region. Should ocean waters penetrate beyond this boundary, the ice-stream buffer would disappear, possibly triggering a collapse of the inland ice reservoir. Aerogeophysical evidence for active volcanism and elevated heat flux beneath the WAIS near the critical region where ice streaming begins is presented.

Hydroxyapatite coating on cobalt alloys using electrophoretic deposition method for bone implant application

NASA Astrophysics Data System (ADS)

Aminatun; M, Shovita; I, Chintya K.; H, Dyah; W, Dwi

2017-05-01

Damage on bone due to osteoporosis and cancer triggered high demand for bone implant prosthesis which is a permanent implant. Thus, a prosthesis coated with hydroxyapatite (HA) is required because it is osteoconductive that can trigger the growth of osteoblast cells. The purpose of this study is to determine the optimum concentration of HA suspension in terms of the surface morphology, coating thickness, adhesion strength and corrosion rate resulting in the HA coating with the best characteristics for bone implant. Coating using electrophoretic deposition (EPD) method with concentrations of 0.02M, 0.04M, 0.06M, 0.08M, and 0.1M was performed on the voltage and time of 120V and 30 minutes respectively. The process was followed by sintering at the temperature of 900 °C for 10 minutes. The results showed that the concentration of HA suspension influences the thickness and the adhesion of layer of HA. The higher the concentration of HA-ethanol suspension the thicker the layer of HA, but its coating adhesion strength values became lower. The concentration of HA suspension of 0.04 M is the best concentration, with characteristics that meet the standards of the bone implant prosthesis. The characteristics are HA coating thickness of 199.93 ± 4.85 μm, the corrosion rate of 0.0018 mmpy and adhesion strength of 4.175 ± 0.716 MPa.

Phylogenetic Analysis of a Microbialite-Forming Microbial Mat from a Hypersaline Lake of the Kiritimati Atoll, Central Pacific

PubMed Central

Schneider, Dominik; Arp, Gernot; Reimer, Andreas; Reitner, Joachim; Daniel, Rolf

2013-01-01

On the Kiritimati atoll, several lakes exhibit microbial mat-formation under different hydrochemical conditions. Some of these lakes trigger microbialite formation such as Lake 21, which is an evaporitic, hypersaline lake (salinity of approximately 170‰). Lake 21 is completely covered with a thick multilayered microbial mat. This mat is associated with the formation of decimeter-thick highly porous microbialites, which are composed of aragonite and gypsum crystals. We assessed the bacterial and archaeal community composition and its alteration along the vertical stratification by large-scale analysis of 16S rRNA gene sequences of the nine different mat layers. The surface layers are dominated by aerobic, phototrophic, and halotolerant microbes. The bacterial community of these layers harbored Cyanobacteria (Halothece cluster), which were accompanied with known phototrophic members of the Bacteroidetes and Alphaproteobacteria. In deeper anaerobic layers more diverse communities than in the upper layers were present. The deeper layers were dominated by Spirochaetes, sulfate-reducing bacteria (Deltaproteobacteria), Chloroflexi (Anaerolineae and Caldilineae), purple non-sulfur bacteria (Alphaproteobacteria), purple sulfur bacteria (Chromatiales), anaerobic Bacteroidetes (Marinilabiacae), Nitrospirae (OPB95), Planctomycetes and several candidate divisions. The archaeal community, including numerous uncultured taxonomic lineages, generally changed from Euryarchaeota (mainly Halobacteria and Thermoplasmata) to uncultured members of the Thaumarchaeota (mainly Marine Benthic Group B) with increasing depth. PMID:23762495

Hardness and microstructure analysis of damaged gear caused by adhesive wear

NASA Astrophysics Data System (ADS)

Mahendra, Rizky Budi; Nugroho, Sri; Ismail, Rifky

2018-03-01

This study was a result from research on repairing project of damaged elevator gear box. The objective of this research is to analyze the failure part on elevator gearbox at flourmill factory. The equipment was damaged after one year installed and running on factory. Severe wear was occurred on high speed helical gear. These helical gear was one of main part of elevator gearbox in flour mill manufacture. Visually, plastic deformation didn't occurred and not visible on the failure helical gear shaft. Some test would be performed to check the chemical composition, microstructure and hardness of failure helical gear. The material of failure helical gear shaft was a medium carbon steel alloy. The microstructure was showed a martensitic phase formed on the surface to the center area of gear shaft. Otherwise, the depth of hardness layer slight formed on surface and lack depth of hardness layer was a main trigger of severe wear. It was not enough to resist wear due to friction caused by rolling and sliding on surface between high speed gear and low speed gear. Enhancement of hardness layer on surface and depth of hardness layer will make the component has more long life time. Furthermore, to perform next research is needed to analyze the reliability of enhanced hardness on layer and depth of hardness layer on helical gear shaft.

Test beam demonstration of silicon microstrip modules with transverse momentum discrimination for the future CMS tracking detector

NASA Astrophysics Data System (ADS)

Adam, W.; Bergauer, T.; Brondolin, E.; Dragicevic, M.; Friedl, M.; Frühwirth, R.; Hoch, M.; Hrubec, J.; König, A.; Steininger, H.; Treberspurg, W.; Waltenberger, W.; Alderweireldt, S.; Beaumont, W.; Janssen, X.; Lauwers, J.; Van Mechelen, P.; Van Remortel, N.; Van Spilbeeck, A.; Beghin, D.; Brun, H.; Clerbaux, B.; De Lentdecker, G.; Delannoy, H.; Fasanella, G.; Favart, L.; Goldouzian, R.; Grebenyuk, A.; Karapostoli, G.; Lenzi, T.; Léonard, A.; Luetic, J.; Maerschalk, T.; Marinov, A.; Postiau, N.; Randle-Conde, A.; Seva, T.; Vanlaer, P.; Vannerom, D.; Yonamine, R.; Wang, Q.; Yang, Y.; Zenoni, F.; Zhang, F.; Abu Zeid, S.; Blekman, F.; De Bruyn, I.; De Clercq, J.; D'Hondt, J.; Deroover, K.; Lowette, S.; Moortgat, S.; Moreels, L.; Python, Q.; Skovpen, K.; Van Mulders, P.; Van Parijs, I.; Bakhshiansohi, H.; Bondu, O.; Brochet, S.; Bruno, G.; Caudron, A.; Delaere, C.; Delcourt, M.; De Visscher, S.; Francois, B.; Giammanco, A.; Jafari, A.; Cabrera Jamoulle, J.; De Favereau De Jeneret, J.; Komm, M.; Krintiras, G.; Lemaitre, V.; Magitteri, A.; Mertens, A.; Michotte, D.; Musich, M.; Piotrzkowski, K.; Quertenmont, L.; Szilasi, N.; Vidal Marono, M.; Wertz, S.; Beliy, N.; Caebergs, T.; Daubie, E.; Hammad, G. H.; Härkönen, J.; Lampén, T.; Luukka, P.; Peltola, T.; Tuominen, E.; Tuovinen, E.; Eerola, P.; Baulieu, G.; Boudoul, G.; Caponetto, L.; Combaret, C.; Contardo, D.; Dupasquier, T.; Gallbit, G.; Lumb, N.; Mirabito, L.; Perries, S.; Vander Donckt, M.; Viret, S.; Agram, J.-L.; Andrea, J.; Bloch, D.; Bonnin, C.; Brom, J.-M.; Chabert, E.; Chanon, N.; Charles, L.; Conte, E.; Fontaine, J.-Ch.; Gross, L.; Hosselet, J.; Jansova, M.; Tromson, D.; Autermann, C.; Feld, L.; Karpinski, W.; Kiesel, K. M.; Klein, K.; Lipinski, M.; Ostapchuk, A.; Pierschel, G.; Preuten, M.; Rauch, M.; Schael, S.; Schomakers, C.; Schulz, J.; Schwering, G.; Wlochal, M.; Zhukov, V.; Pistone, C.; Fluegge, G.; Kuensken, A.; Pooth, O.; Stahl, A.; Aldaya, M.; Asawatangtrakuldee, C.; Beernaert, K.; Bertsche, D.; Contreras-Campana, C.; Eckerlin, G.; Eckstein, D.; Eichhorn, T.; Gallo, E.; Garay Garcia, J.; Hansen, K.; Haranko, M.; Harb, A.; Hauk, J.; Keaveney, J.; Kalogeropoulos, A.; Kleinwort, C.; Lohmann, W.; Mankel, R.; Maser, H.; Mittag, G.; Muhl, C.; Mussgiller, A.; Pitzl, D.; Reichelt, O.; Savitskyi, M.; Schuetze, P.; Walsh, R.; Zuber, A.; Biskop, H.; Buhmann, P.; Centis-Vignali, M.; Garutti, E.; Haller, J.; Hoffmann, M.; Klanner, R.; Matysek, M.; Perieanu, A.; Scharf, Ch.; Schleper, P.; Schmidt, A.; Schwandt, J.; Sonneveld, J.; Steinbrück, G.; Vormwald, B.; Wellhausen, J.; Abbas, M.; Amstutz, C.; Barvich, T.; Barth, Ch.; Boegelspacher, F.; De Boer, W.; Butz, E.; Casele, M.; Colombo, F.; Dierlamm, A.; Freund, B.; Hartmann, F.; Heindl, S.; Husemann, U.; Kornmeyer, A.; Kudella, S.; Muller, Th.; Printz, M.; Simonis, H. J.; Steck, P.; Weber, M.; Weiler, Th.; Anagnostou, G.; Asenov, P.; Assiouras, P.; Daskalakis, G.; Kyriakis, A.; Loukas, D.; Paspalaki, L.; Siklér, F.; Veszprémi, V.; Bhardwaj, A.; Dalal, R.; Jain, G.; Ranjan, K.; Dutta, S.; Chowdhury, S. Roy; Bakhshiansohl, H.; Behnamian, H.; Khakzad, M.; Naseri, M.; Cariola, P.; Creanza, D.; De Palma, M.; De Robertis, G.; Fiore, L.; Franco, M.; Loddo, F.; Sala, G.; Silvestris, L.; Maggi, G.; My, S.; Selvaggi, G.; Albergo, S.; Costa, S.; Di Mattia, A.; Giordano, F.; Potenza, R.; Saizu, M. A.; Tricomi, A.; Tuve, C.; Barbagli, G.; Brianzi, M.; Ciaranfi, R.; Ciulli, V.; Civinini, C.; D'Alessandro, R.; Focardi, E.; Latino, G.; Lenzi, P.; Meschini, M.; Paoletti, S.; Russo, L.; Scarlini, E.; Sguazzoni, G.; Strom, D.; Viliani, L.; Ferro, F.; Lo Vetere, M.; Robutti, E.; Dinardo, M. E.; Fiorendi, S.; Gennai, S.; Malvezzi, S.; Manzoni, R. A.; Menasce, D.; Moroni, L.; Pedrini, D.; Azzi, P.; Bacchetta, N.; Bisello, D.; Dall'Osso, M.; Pozzobon, N.; Tosi, M.; De Canio, F.; Gaioni, L.; Manghisoni, M.; Nodari, B.; Riceputi, E.; Re, V.; Traversi, G.; Comotti, D.; Ratti, L.; Alunni Solestizi, L.; Biasini, M.; Bilei, G. M.; Cecchi, C.; Checcucci, B.; Ciangottini, D.; Fanò, L.; Gentsos, C.; Ionica, M.; Leonardi, R.; Manoni, E.; Mantovani, G.; Marconi, S.; Mariani, V.; Menichelli, M.; Modak, A.; Morozzi, A.; Moscatelli, F.; Passeri, D.; Placidi, P.; Postolache, V.; Rossi, A.; Saha, A.; Santocchia, A.; Storchi, L.; Spiga, D.; Androsov, K.; Azzurri, P.; Arezzini, S.; Bagliesi, G.; Basti, A.; Boccali, T.; Borrello, L.; Bosi, F.; Castaldi, R.; Ciampa, A.; Ciocci, M. A.; Dell'Orso, R.; Donato, S.; Fedi, G.; Giassi, A.; Grippo, M. T.; Ligabue, F.; Lomtadze, T.; Magazzu, G.; Martini, L.; Mazzoni, E.; Messineo, A.; Moggi, A.; Morsani, F.; Palla, F.; Palmonari, F.; Raffaelli, F.; Rizzi, A.; Savoy-Navarro, A.; Spagnolo, P.; Tenchini, R.; Tonelli, G.; Venturi, A.; Verdini, P. G.; Bellan, R.; Costa, M.; Covarelli, R.; Da Rocha Rolo, M.; Demaria, N.; Rivetti, A.; Dellacasa, G.; Mazza, G.; Migliore, E.; Monteil, E.; Pacher, L.; Ravera, F.; Solano, A.; Fernandez, M.; Gomez, G.; Jaramillo Echeverria, R.; Moya, D.; Gonzalez Sanchez, F. J.; Vila, I.; Virto, A. L.; Abbaneo, D.; Ahmed, I.; Albert, E.; Auzinger, G.; Berruti, G.; Bianchi, G.; Blanchot, G.; Bonnaud, J.; Caratelli, A.; Ceresa, D.; Christiansen, J.; Cichy, K.; Daguin, J.; D'Auria, A.; Detraz, S.; Deyrail, D.; Dondelewski, O.; Faccio, F.; Frank, N.; Gadek, T.; Gill, K.; Honma, A.; Hugo, G.; Jara Casas, L. M.; Kaplon, J.; Kornmayer, A.; Kottelat, L.; Kovacs, M.; Krammer, M.; Lenoir, P.; Mannelli, M.; Marchioro, A.; Marconi, S.; Mersi, S.; Martina, S.; Michelis, S.; Moll, M.; Onnela, A.; Orfanelli, S.; Pavis, S.; Peisert, A.; Pernot, J.-F.; Petagna, P.; Petrucciani, G.; Postema, H.; Rose, P.; Tropea, P.; Troska, J.; Tsirou, A.; Vasey, F.; Vichoudis, P.; Verlaat, B.; Zwalinski, L.; Bachmair, F.; Becker, R.; di Calafiori, D.; Casal, B.; Berger, P.; Djambazov, L.; Donega, M.; Grab, C.; Hits, D.; Hoss, J.; Kasieczka, G.; Lustermann, W.; Mangano, B.; Marionneau, M.; Martinez Ruiz del Arbol, P.; Masciovecchio, M.; Meinhard, M.; Perozzi, L.; Roeser, U.; Starodumov, A.; Tavolaro, V.; Wallny, R.; Zhu, D.; Amsler, C.; Bösiger, K.; Caminada, L.; Canelli, F.; Chiochia, V.; de Cosa, A.; Galloni, C.; Hreus, T.; Kilminster, B.; Lange, C.; Maier, R.; Ngadiuba, J.; Pinna, D.; Robmann, P.; Taroni, S.; Yang, Y.; Bertl, W.; Deiters, K.; Erdmann, W.; Horisberger, R.; Kaestli, H.-C.; Kotlinski, D.; Langenegger, U.; Meier, B.; Rohe, T.; Streuli, S.; Chen, P.-H.; Dietz, C.; Grundler, U.; Hou, W.-S.; Lu, R.-S.; Moya, M.; Cussans, D.; Flacher, H.; Goldstein, J.; Grimes, M.; Jacob, J.; Seif El Nasr-Storey, S.; Cole, J.; Hoad, C.; Hobson, P.; Morton, A.; Reid, I. D.; Auzinger, G.; Bainbridge, R.; Dauncey, P.; Fulcher, J.; Hall, G.; James, T.; Magnan, A.-M.; Pesaresi, M.; Raymond, D. M.; Uchida, K.; Braga, D.; Coughlan, J. A.; Harder, K.; Jones, L.; Ilic, J.; Murray, P.; Prydderch, M.; Tomalin, I. R.; Garabedian, A.; Heintz, U.; Narain, M.; Nelson, J.; Sagir, S.; Speer, T.; Swanson, J.; Tersegno, D.; Watson-Daniels, J.; Chertok, M.; Conway, J.; Conway, R.; Flores, C.; Lander, R.; Pellett, D.; Ricci-Tam, F.; Squires, M.; Thomson, J.; Yohay, R.; Burt, K.; Ellison, J.; Hanson, G.; Olmedo, M.; Si, W.; Yates, B. R.; Gerosa, R.; Sharma, V.; Vartak, A.; Yagil, A.; Zevi Della Porta, G.; Dutta, V.; Gouskos, L.; Incandela, J.; Kyre, S.; Mullin, S.; Qu, H.; White, D.; Dominguez, A.; Bartek, R.; Cumalat, J. P.; Ford, W. T.; Jensen, F.; Johnson, A.; Krohn, M.; Leontsinis, S.; Mulholland, T.; Stenson, K.; Wagner, S. R.; Apresyan, A.; Bolla, G.; Burkett, K.; Butler, J. N.; Cheung, H. W. K.; Chramowicz, J.; Christian, D.; Cooper, W. E.; Deptuch, G.; Derylo, G.; Gingu, C.; Grünendahl, S.; Hasegawa, S.; Hoff, J.; Howell, J.; Hrycyk, M.; Jindariani, S.; Johnson, M.; Kahlid, F.; Lei, C. M.; Lipton, R.; Lopes De Sá, R.; Liu, T.; Los, S.; Matulik, M.; Merkel, P.; Nahn, S.; Prosser, A.; Rivera, R.; Schneider, B.; Sellberg, G.; Shenai, A.; Spiegel, L.; Tran, N.; Uplegger, L.; Voirin, E.; Berry, D. R.; Chen, X.; Ennesser, L.; Evdokimov, A.; Evdokimov, O.; Gerber, C. E.; Hofman, D. J.; Makauda, S.; Mills, C.; Sandoval Gonzalez, I. D.; Alimena, J.; Antonelli, L. J.; Francis, B.; Hart, A.; Hill, C. S.; Parashar, N.; Stupak, J.; Bortoletto, D.; Bubna, M.; Hinton, N.; Jones, M.; Miller, D. H.; Shi, X.; Tan, P.; Baringer, P.; Bean, A.; Khalil, S.; Kropivnitskaya, A.; Majumder, D.; Wilson, G.; Ivanov, A.; Mendis, R.; Mitchell, T.; Skhirtladze, N.; Taylor, R.; Anderson, I.; Fehling, D.; Gritsan, A.; Maksimovic, P.; Martin, C.; Nash, K.; Osherson, M.; Swartz, M.; Xiao, M.; Acosta, J. G.; Cremaldi, L. M.; Oliveros, S.; Perera, L.; Summers, D.; Bloom, K.; Claes, D. R.; Fangmeier, C.; Gonzalez Suarez, R.; Monroy, J.; Siado, J.; Hahn, K.; Sevova, S.; Sung, K.; Trovato, M.; Bartz, E.; Gershtein, Y.; Halkiadakis, E.; Kyriacou, S.; Lath, A.; Nash, K.; Osherson, M.; Schnetzer, S.; Stone, R.; Walker, M.; Malik, S.; Norberg, S.; Ramirez Vargas, J. E.; Alyari, M.; Dolen, J.; Godshalk, A.; Harrington, C.; Iashvili, I.; Kharchilava, A.; Nguyen, D.; Parker, A.; Rappoccio, S.; Roozbahani, B.; Alexander, J.; Chaves, J.; Chu, J.; Dittmer, S.; McDermott, K.; Mirman, N.; Rinkevicius, A.; Ryd, A.; Salvati, E.; Skinnari, L.; Soffi, L.; Tao, Z.; Thom, J.; Tucker, J.; Zientek, M.; Akgün, B.; Ecklund, K. M.; Kilpatrick, M.; Nussbaum, T.; Zabel, J.; Betchart, B.; Covarelli, R.; Demina, R.; Hindrichs, O.; Petrillo, G.; Eusebi, R.; Patel, R.; Perloff, A.; Ulmer, K. A.; Delannoy, A. G.; D'Angelo, P.; Johns, W.

2018-03-01

A new CMS Tracker is under development for operation at the High Luminosity LHC from 2026 onwards. It includes an outer tracker based on dedicated modules that will reconstruct short track segments, called stubs, using spatially coincident clusters in two closely spaced silicon sensor layers. These modules allow the rejection of low transverse momentum track hits and reduce the data volume before transmission to the first level trigger. The inclusion of tracking information in the trigger decision is essential to limit the first level trigger accept rate. A customized front-end readout chip, the CMS Binary Chip (CBC), containing stub finding logic has been designed for this purpose. A prototype module, equipped with the CBC chip, has been constructed and operated for the first time in a 4 GeemVem/emc positron beam at DESY. The behaviour of the stub finding was studied for different angles of beam incidence on a module, which allows an estimate of the sensitivity to transverse momentum within the future CMS detector. A sharp transverse momentum threshold around 2 emVem/emc was demonstrated, which meets the requirement to reject a large fraction of low momentum tracks present in the LHC environment on-detector. This is the first realistic demonstration of a silicon tracking module that is able to select data, based on the particle's transverse momentum, for use in a first level trigger at the LHC . The results from this test are described here.

Comparison of earthquake-triggered turbidites from the Saguenay (Eastern Canada) and Reloncavi (Chilean margin) Fjords: Implications for paleoseismicity and sedimentology

NASA Astrophysics Data System (ADS)

St-Onge, Guillaume; Chapron, Emmanuel; Mulsow, Sandor; Salas, Marcos; Viel, Matias; Debret, Maxime; Foucher, Anthony; Mulder, Thierry; Winiarski, Thierry; Desmet, Marc; Costa, Pedro J. M.; Ghaleb, Bassam; Jaouen, Alain; Locat, Jacques

2012-01-01

High-resolution seismic profiles along with physical and sedimentological properties of sediment cores from the Saguenay (Eastern Canada) and Reloncavi (Chile) Fjords allowed the identification of several decimeter to meter-thick turbidites. In both fjords, the turbidites were associated with large magnitude historic and pre-historic earthquakes including the 1663 AD (M > 7) earthquake in the Saguenay Fjord, and the 1960 (M 9.5), 1837 (M ~ 8) and 1575 AD major Chilean subduction earthquakes in the Reloncavi Fjord. In addition, a sand layer with exoscopic characteristics typical of a tsunami deposit was observed immediately above the turbidite associated with the 1575 AD earthquake in the Reloncavi Fjord and supports both the chronology and the large magnitude of that historic earthquake. In the Saguenay Fjord, the earthquake-triggered turbidites are sometimes underlying a hyperpycnite associated with the rapid breaching and draining of a natural dam formed by earthquake-triggered landslides. Similar hyperpycnal floods were also recorded in historical and continental geological archives for the 1960 and 1575 AD Chilean subduction earthquakes, highlighting the risk of such flood events several weeks or months after main earthquake. In both fjords, as well as in other recently recognized earthquake-triggered turbidites, the decimeter-to meter-thick normally-graded turbidites are characterized by a homogeneous, but slightly fining upward tail. Finally, this paper also emphasizes the sensitivity of fjords to record historic and pre-historic seismicity.

The South African Astronomical Observatory instrumentation software architecture and the SHOC instruments

NASA Astrophysics Data System (ADS)

van Gend, Carel; Lombaard, Briehan; Sickafoose, Amanda; Whittal, Hamish

2016-07-01

Until recently, software for instruments on the smaller telescopes at the South African Astronomical Observatory (SAAO) has not been designed for remote accessibility and frequently has not been developed using modern software best-practice. We describe a software architecture we have implemented for use with new and upgraded instruments at the SAAO. The architecture was designed to allow for multiple components and to be fast, reliable, remotely- operable, support different user interfaces, employ as much non-proprietary software as possible, and to take future-proofing into consideration. Individual component drivers exist as standalone processes, communicating over a network. A controller layer coordinates the various components, and allows a variety of user interfaces to be used. The Sutherland High-speed Optical Cameras (SHOC) instruments incorporate an Andor electron-multiplying CCD camera, a GPS unit for accurate timing and a pair of filter wheels. We have applied the new architecture to the SHOC instruments, with the camera driver developed using Andor's software development kit. We have used this to develop an innovative web-based user-interface to the instrument.

Luminance compensation for AMOLED displays using integrated MIS sensors

NASA Astrophysics Data System (ADS)

Vygranenko, Yuri; Fernandes, Miguel; Louro, Paula; Vieira, Manuela

2017-05-01

Active-matrix organic light-emitting diodes (AMOLEDs) are ideal for future TV applications due to their ability to faithfully reproduce real images. However, pixel luminance can be affected by instability of driver TFTs and aging effect in OLEDs. This paper reports on a pixel driver utilizing a metal-insulator-semiconductor (MIS) sensor for luminance control of the OLED element. In the proposed pixel architecture for bottom-emission AMOLEDs, the embedded MIS sensor shares the same layer stack with back-channel etched a Si:H TFTs to maintain the fabrication simplicity. The pixel design for a large-area HD display is presented. The external electronics performs image processing to modify incoming video using correction parameters for each pixel in the backplane, and also sensor data processing to update the correction parameters. The luminance adjusting algorithm is based on realistic models for pixel circuit elements to predict the relation between the programming voltage and OLED luminance. SPICE modeling of the sensing part of the backplane is performed to demonstrate its feasibility. Details on the pixel circuit functionality including the sensing and programming operations are also discussed.

Evaluation of a High Temperature SOI Half-Bridge MOSFET Driver, Type CHT-HYPERION

NASA Technical Reports Server (NTRS)

Patterson, Richard; Hammoud, Ahmad

2010-01-01

Silicon-On-Insulator (SOI) technology utilizes the addition of an insulation layer in its structure to reduce leakage currents and to minimize parasitic junctions. As a result, SOIbased devices exhibit reduced internal heating as compared to the conventional silicon devices, consume less power, and can withstand higher operating temperatures. In addition, SOI electronic integrated circuits display good tolerance to radiation by virtue of introducing barriers or lengthening the path for penetrating particles and/or providing a region for trapping incident ionization. The benefits of these parts make them suitable for use in deep space and planetary exploration missions where extreme temperatures and radiation are encountered. Although designed for high temperatures, very little data exist on the operation of SOI devices and circuits at cryogenic temperatures. In this work, the performance of a commercial-off-the-shelf (COTS) SOI half-bridge driver integrated circuit was evaluated under extreme temperatures and thermal cycling. The investigations were carried out to establish a baseline on the functionality and to determine suitability of this device for use in space exploration missions under extreme temperature conditions.

Assessment of pseudo-bilayer structures in the heterogate germanium electron-hole bilayer tunnel field-effect transistor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Padilla, J. L., E-mail: jose.padilladelatorre@epfl.ch; Alper, C.; Ionescu, A. M.

2015-06-29

We investigate the effect of pseudo-bilayer configurations at low operating voltages (≤0.5 V) in the heterogate germanium electron-hole bilayer tunnel field-effect transistor (HG-EHBTFET) compared to the traditional bilayer structures of EHBTFETs arising from semiclassical simulations where the inversion layers for electrons and holes featured very symmetric profiles with similar concentration levels at the ON-state. Pseudo-bilayer layouts are attained by inducing a certain asymmetry between the top and the bottom gates so that even though the hole inversion layer is formed at the bottom of the channel, the top gate voltage remains below the required value to trigger the formation of themore » inversion layer for electrons. Resulting benefits from this setup are improved electrostatic control on the channel, enhanced gate-to-gate efficiency, and higher I{sub ON} levels. Furthermore, pseudo-bilayer configurations alleviate the difficulties derived from confining very high opposite carrier concentrations in very thin structures.« less

Simultaneous monitoring of humidity and chemical changes using quartz crystal microbalance sensors modified with nano-thin films.

PubMed

Selyanchyn, Roman; Korposh, Serhiy; Wakamatsu, Shunichi; Lee, Seung-Woo

2011-01-01

Quartz crystal microbalance (QCM) electrodes modified with nano-thin films were used to develop a system for measuring significant environment changes (smoke, humidity, hazardous material release). A layer-by-layer approach was used for the deposition of sensitive coatings with a nanometer thickness on the electrode surface. The QCM electrode was modified with self-assembled alternate layers of tetrakis-(4-sulfophenyl) porphine (TSPP) (or its manganese derivative, MnTSPP) and poly(diallyldimethylammonium chloride) (PDDA). The QCM sensors, which had been reported previously for humidity sensing purposes, revealing a high possibility to recognize significant environmental changes. Identifying of the origin of environmental change is possible via differential signal analysis of the obtained data. The sensors showed different responses to humidity changes, hazardous gas (ammonia) or cigarette smoke exposure. Even qualitative analysis is not yet available; it has been shown that ventilation triggers or alarms for monitoring smoke or hazardous material release can be built using the obtained result.

Dielectric-wall linear accelerator with a high voltage fast rise time switch that includes a pair of electrodes between which are laminated alternating layers of isolated conductors and insulators

DOEpatents

Caporaso, G.J.; Sampayan, S.E.; Kirbie, H.C.

1998-10-13

A dielectric-wall linear accelerator is improved by a high-voltage, fast rise-time switch that includes a pair of electrodes between which are laminated alternating layers of isolated conductors and insulators. A high voltage is placed between the electrodes sufficient to stress the voltage breakdown of the insulator on command. A light trigger, such as a laser, is focused along at least one line along the edge surface of the laminated alternating layers of isolated conductors and insulators extending between the electrodes. The laser is energized to initiate a surface breakdown by a fluence of photons, thus causing the electrical switch to close very promptly. Such insulators and lasers are incorporated in a dielectric wall linear accelerator with Blumlein modules, and phasing is controlled by adjusting the length of fiber optic cables that carry the laser light to the insulator surface. 12 figs.

Dielectric-wall linear accelerator with a high voltage fast rise time switch that includes a pair of electrodes between which are laminated alternating layers of isolated conductors and insulators

DOEpatents

Caporaso, George J.; Sampayan, Stephen E.; Kirbie, Hugh C.

1998-01-01

A dielectric-wall linear accelerator is improved by a high-voltage, fast rise-time switch that includes a pair of electrodes between which are laminated alternating layers of isolated conductors and insulators. A high voltage is placed between the electrodes sufficient to stress the voltage breakdown of the insulator on command. A light trigger, such as a laser, is focused along at least one line along the edge surface of the laminated alternating layers of isolated conductors and insulators extending between the electrodes. The laser is energized to initiate a surface breakdown by a fluence of photons, thus causing the electrical switch to close very promptly. Such insulators and lasers are incorporated in a dielectric wall linear accelerator with Blumlein modules, and phasing is controlled by adjusting the length of fiber optic cables that carry the laser light to the insulator surface.

Photoelectrical Stimulation of Neuronal Cells by an Organic Semiconductor-Electrolyte Interface.

PubMed

Abdullaeva, Oliya S; Schulz, Matthias; Balzer, Frank; Parisi, Jürgen; Lützen, Arne; Dedek, Karin; Schiek, Manuela

2016-08-23

As a step toward the realization of neuroprosthetics for vision restoration, we follow an electrophysiological patch-clamp approach to study the fundamental photoelectrical stimulation mechanism of neuronal model cells by an organic semiconductor-electrolyte interface. Our photoactive layer consisting of an anilino-squaraine donor blended with a fullerene acceptor is supporting the growth of the neuronal model cell line (N2A cells) without an adhesion layer on it and is not impairing cell viability. The transient photocurrent signal upon illumination from the semiconductor-electrolyte layer is able to trigger a passive response of the neuronal cells under physiological conditions via a capacitive coupling mechanism. We study the dynamics of the capacitive transmembrane currents by patch-clamp recordings and compare them to the dynamics of the photocurrent signal and its spectral responsivity. Furthermore, we characterize the morphology of the semiconductor-electrolyte interface by atomic force microscopy and study the stability of the interface in dark and under illuminated conditions.

Anisotropic dielectric phase transition triggered by pendulum-like motion coupled with proton transfer in a layered hybrid crystalline material (4-nitroanilinium+) (18-crown-6) (H2PO4-) (H3PO4)2

NASA Astrophysics Data System (ADS)

Liu, Yang; Zhu, Chun-li; Qin, Liu-lei; Zheng, Xiao-yuan; Liu, Zun-qi

2018-07-01

The organic-inorganic hybrid phase-transition material, (4-nitroanilinium+) (18-crown-6) (H2PO4-) (H3PO4)2 (1), was successfully synthesized. The organic (4-nitroanilinium) (18-crown-6)+ supramolecular cation layer and inorganic phosphate anion layer were arranged alternately. Differential scanning calorimetry (DSC), temperature-dependent dielectric measurements, and variable-temperature single-crystal X-ray diffraction analysis confirmed the reversible isostructural phase transition of 1 with the same space group Pbca at 225 K, wherein the synergistic effect between the pendulum-like motion of organic cations and the proton transfer in the Osbnd H⋯O hydrogen bonding of inorganic anions was mainly responsible for the phase-transition behavior of 1. The most striking dielectric property was the remarkable anisotropy along various crystallographic axes. A potential-energy calculation further supported the possibility of dynamic motion of cations in the crystal.

Livestock systems and rangeland degradation in the new World Atlas of Desertification

NASA Astrophysics Data System (ADS)

Zucca, Claudio; Reynolds, James F.; Cherlet, Michael

2015-04-01

Livestock systems and rangeland degradation in the new World Atlas of Desertification Land degradation and desertification (LDD), which are widespread in global rangelands, are complex processes. They are caused by multiple (but limited) number of biophysical and socioeconomic drivers that lead to an unbalance in the capacity of the land to sustainably produce ecosystem services and economic value. Converging evidence indicates that the key biophysical and socioeconomic drivers include agricultural or pastoral land use and management practices, population growth, societal demands (e.g., urbanization), and climate change (e.g., increasing aridity and drought). The new World Atlas of Desertification (WAD) describes these global issues, documents their spatial change, and highlights the importance of these drivers in relation to land degradation processes. The impacts of LDD on the atmosphere, on water and on biodiversity are also covered. The WAD spatially illustrates relevant types of livestock and rangeland management systems, related (over-under) use of resources, various management activities, and some of the common features and transitions that contribute to LDD. For example, livestock grazing in marginal areas is increasing due to competition with agricultural encroachment and, hence, vulnerable lands are under threat. The integration of stratified global data layers facilitates identifying areas where stress on the land system can be linked to underlying causal issues. One of the objectives of the new WAD is to provide synthesis and tools for scientists and stakeholders to design sustainable solutions for efficient land use in global rangelands.

Seasonal prediction of lightning activity in North Western Venezuela: Large-scale versus local drivers

NASA Astrophysics Data System (ADS)

Muñoz, Á. G.; Díaz-Lobatón, J.; Chourio, X.; Stock, M. J.

2016-05-01

The Lake Maracaibo Basin in North Western Venezuela has the highest annual lightning rate of any place in the world (~ 200 fl km- 2 yr- 1), whose electrical discharges occasionally impact human and animal lives (e.g., cattle) and frequently affect economic activities like oil and natural gas exploitation. Lightning activity is so common in this region that it has a proper name: Catatumbo Lightning (plural). Although short-term lightning forecasts are now common in different parts of the world, to the best of the authors' knowledge, seasonal prediction of lightning activity is still non-existent. This research discusses the relative role of both large-scale and local climate drivers as modulators of lightning activity in the region, and presents a formal predictability study at seasonal scale. Analysis of the Catatumbo Lightning Regional Mode, defined in terms of the second Empirical Orthogonal Function of monthly Lightning Imaging Sensor (LIS-TRMM) and Optical Transient Detector (OTD) satellite data for North Western South America, permits the identification of potential predictors at seasonal scale via a Canonical Correlation Analysis. Lightning activity in North Western Venezuela responds to well defined sea-surface temperature patterns (e.g., El Niño-Southern Oscillation, Atlantic Meridional Mode) and changes in the low-level meridional wind field that are associated with the Inter-Tropical Convergence Zone migrations, the Caribbean Low Level Jet and tropical cyclone activity, but it is also linked to local drivers like convection triggered by the topographic configuration and the effect of the Maracaibo Basin Nocturnal Low Level Jet. The analysis indicates that at seasonal scale the relative contribution of the large-scale drivers is more important than the local (basin-wide) ones, due to the synoptic control imposed by the former. Furthermore, meridional CAPE transport at 925 mb is identified as the best potential predictor for lightning activity in the Lake Maracaibo Basin. It is found that the predictive skill is slightly higher for the minimum lightning season (Jan-Feb) than for the maximum one (Sep-Oct), but that in general the skill is high enough to be useful for decision-making processes related to human safety, oil and natural gas exploitation, energy and food security.

Mechanism of Gaseous Detonation Propagation Through Reactant Layers Bounded by Inert Gas

NASA Astrophysics Data System (ADS)

Houim, Ryan

2017-11-01

Vapor cloud explosions and rotating detonation engines involve the propagation of gaseous detonations through a layer of reactants that is bounded by inert gas. Mechanistic understanding of how detonations propagate stably or fail in these scenarios is incomplete. Numerical simulations were used to investigate mechanisms of gaseous detonation propagation through reactant layers bounded by inert gas. The reactant layer was a stoichiometric mixture of C2H4/O2 at 1 atm and 300K and is 4 detonation cells in height. Cases where the inert gas temperature was 300, 1500, and 3500 K will be discussed. The detonation failed for the 300 K case and propagated marginally for the 1500 K case. Surprisingly, the detonation propagated stably for the 3500 K case. A shock structure forms that involves a detached shock in the inert gas and a series of oblique shocks in the reactants. A small local explosion is triggered when the Mach stem of a detonation cell interacts with the compressed reactants behind one of these oblique shocks. The resulting pressure wave produces a new Mach stem and a new triple point that leads to a stable detonation. Preliminary results on the influence of a deflagration at the inert/reactant interface on the stability of a layered detonation will be discussed.

Developing Present-day Proxy Cases Based on NARVAL Data for Investigating Low Level Cloud Responses to Future Climate Change.

NASA Astrophysics Data System (ADS)

Reilly, Stephanie

2017-04-01

The energy budget of the entire global climate is significantly influenced by the presence of boundary layer clouds. The main aim of the High Definition Clouds and Precipitation for Advancing Climate Prediction (HD(CP)2) project is to improve climate model predictions by means of process studies of clouds and precipitation. This study makes use of observed elevated moisture layers as a proxy of future changes in tropospheric humidity. The associated impact on radiative transfer triggers fast responses in boundary layer clouds, providing a framework for investigating this phenomenon. The investigation will be carried out using data gathered during the Next-generation Aircraft Remote-sensing for VALidation (NARVAL) South campaigns. Observational data will be combined with ECMWF reanalysis data to derive the large scale forcings for the Large Eddy Simulations (LES). Simulations will be generated for a range of elevated moisture layers, spanning a multi-dimensional phase space in depth, amplitude, elevation, and cloudiness. The NARVAL locations will function as anchor-points. The results of the large eddy simulations and the observations will be studied and compared in an attempt to determine how simulated boundary layer clouds react to changes in radiative transfer from the free troposphere. Preliminary LES results will be presented and discussed.

Effects of fire on the thermal stability of permafrost in lowland and upland black spruce forests of interior Alaska in a changing climate

USGS Publications Warehouse

Jafarov, Elchin E.; Romanovsky, Vladimir E.; Genet, Helene; McGuire, Anthony David; Marchenko, Sergey S.

2013-01-01

Fire is an important factor controlling the composition and thickness of the organic layer in the black spruce forest ecosystems of interior Alaska. Fire that burns the organic layer can trigger dramatic changes in the underlying permafrost, leading to accelerated ground thawing within a relatively short time. In this study, we addressed the following questions. (1) Which factors determine post-fire ground temperature dynamics in lowland and upland black spruce forests? (2) What levels of burn severity will cause irreversible permafrost degradation in these ecosystems? We evaluated these questions in a transient modeling–sensitivity analysis framework to assess the sensitivity of permafrost to climate, burn severity, soil organic layer thickness, and soil moisture content in lowland (with thick organic layers, ~80 cm) and upland (with thin organic layers, ~30 cm) black spruce ecosystems. The results indicate that climate warming accompanied by fire disturbance could significantly accelerate permafrost degradation. In upland black spruce forest, permafrost could completely degrade in an 18 m soil column within 120 years of a severe fire in an unchanging climate. In contrast, in a lowland black spruce forest, permafrost is more resilient to disturbance and can persist under a combination of moderate burn severity and climate warming.

Interannual drivers of the seasonal cycle of CO2 in the Southern Ocean

NASA Astrophysics Data System (ADS)

Gregor, Luke; Kok, Schalk; Monteiro, Pedro M. S.

2018-04-01

Resolving and understanding the drivers of variability of CO2 in the Southern Ocean and its potential climate feedback is one of the major scientific challenges of the ocean-climate community. Here we use a regional approach on empirical estimates of pCO2 to understand the role that seasonal variability has in long-term CO2 changes in the Southern Ocean. Machine learning has become the preferred empirical modelling tool to interpolate time- and location-restricted ship measurements of pCO2. In this study we use an ensemble of three machine-learning products: support vector regression (SVR) and random forest regression (RFR) from Gregor et al. (2017), and the self-organising-map feed-forward neural network (SOM-FFN) method from Landschützer et al. (2016). The interpolated estimates of ΔpCO2 are separated into nine regions in the Southern Ocean defined by basin (Indian, Pacific, and Atlantic) and biomes (as defined by Fay and McKinley, 2014a). The regional approach shows that, while there is good agreement in the overall trend of the products, there are periods and regions where the confidence in estimated ΔpCO2 is low due to disagreement between the products. The regional breakdown of the data highlighted the seasonal decoupling of the modes for summer and winter interannual variability. Winter interannual variability had a longer mode of variability compared to summer, which varied on a 4-6-year timescale. We separate the analysis of the ΔpCO2 and its drivers into summer and winter. We find that understanding the variability of ΔpCO2 and its drivers on shorter timescales is critical to resolving the long-term variability of ΔpCO2. Results show that ΔpCO2 is rarely driven by thermodynamics during winter, but rather by mixing and stratification due to the stronger correlation of ΔpCO2 variability with mixed layer depth. Summer pCO2 variability is consistent with chlorophyll a variability, where higher concentrations of chlorophyll a correspond with lower pCO2 concentrations. In regions of low chlorophyll a concentrations, wind stress and sea surface temperature emerged as stronger drivers of ΔpCO2. In summary we propose that sub-decadal variability is explained by summer drivers, while winter variability contributes to the long-term changes associated with the SAM. This approach is a useful framework to assess the drivers of ΔpCO2 but would greatly benefit from improved estimates of ΔpCO2 and a longer time series.

Arctic mosses govern below-ground environment and ecosystem processes.

PubMed

Gornall, J L; Jónsdóttir, I S; Woodin, S J; Van der Wal, R

2007-10-01

Mosses dominate many northern ecosystems and their presence is integral to soil thermal and hydrological regimes which, in turn, dictate important ecological processes. Drivers, such as climate change and increasing herbivore pressure, affect the moss layer thus, assessment of the functional role of mosses in determining soil characteristics is essential. Field manipulations conducted in high arctic Spitsbergen (78 degrees N), creating shallow (3 cm), intermediate (6 cm) and deep (12 cm) moss layers over the soil surface, had an immediate impact on soil temperature in terms of both average temperatures and amplitude of fluctuations. In soil under deep moss, temperature was substantially lower and organic layer thaw occurred 4 weeks later than in other treatment plots; the growing season for vascular plants was thereby reduced by 40%. Soil moisture was also reduced under deep moss, reflecting the influence of local heterogeneity in moss depth, over and above the landscape-scale topographic control of soil moisture. Data from field and laboratory experiments show that moss-mediated effects on the soil environment influenced microbial biomass and activity, resulting in warmer and wetter soil under thinner moss layers containing more plant-available nitrogen. In arctic ecosystems, which are limited by soil temperature, growing season length and nutrient availability, spatial and temporal variation in the depth of the moss layer has significant repercussions for ecosystem function. Evidence from our mesic tundra site shows that any disturbance causing reduction in the depth of the moss layer will alleviate temperature and moisture constraints and therefore profoundly influence a wide range of ecosystem processes, including nutrient cycling and energy transfer.

Time-dependent Calculations of an Impact-triggered Runaway Greenhouse Atmosphere on Mars

NASA Technical Reports Server (NTRS)

Segura, T. L.; Toon, O. B.; Colaprete, A.

2003-01-01

Large asteroid and comet impacts result in the production of thick (greater than tens of meters) global debris layers of 1500+ K and the release through precipitation of impact-injected steam and melting ground ice) of large amounts (greater than tens of meters global equivalent thickness) of water on the surface of Mars. Modeling shows that the surface of Mars is still above the freezing point of water after the rainout of the impact-injected steam and melting of subsurface ice. The energy remaining in the hot debris layer will allow evaporation of this water back into the atmosphere where it may rain out at a later time. Given a sufficiently rapid supply of this water to the atmosphere it will initiate a temporary "runaway" greenhouse state.

Poly(N-isopropylacrylamide) hydrogel-based shape-adjustable polyimide films triggered by near-human-body temperature.

PubMed

Huanqing Cui; Xuemin Du; Juan Wang; Tianhong Tang; Tianzhun Wu

2016-08-01

Hydrogel-based shape-adjustable films were successfully fabricated via grafting poly(N-isopropylacrylamide) (PNIPAM) onto one side of polyimide (PI) films. The prepared PI-g-PNIPAM films exhibited rapid, reversible, and repeatable bending/unbending property by heating to near-human-body temperature (37 °C) or cooling to 25 °C. The excellent property of PI-g-PNIPAM films resulted from a lower critical solution temperature (LCST) of PNIPAM at about 32 °C. Varying the thickness of PNIPAM hydrogel layer regulated the thermo-responsive shape bending degree and response speed of PI-g-PNIPAM films. The thermo-induced shrinkage of hydrogel layers can tune the curvature of PI films, which have potential applications in the field of wearable and implantable devices.

Collagen implants equipped with 'fish scale'-like nanoreservoirs of growth factors for bone regeneration.

PubMed

Eap, Sandy; Ferrand, Alice; Schiavi, Jessica; Keller, Laetitia; Kokten, Tunay; Fioretti, Florence; Mainard, Didier; Ladam, Guy; Benkirane-Jessel, Nadia

2014-01-01

Implants triggering rapid, robust and durable tissue regeneration are needed to shorten recovery times and decrease risks of postoperative complications for patients. Here, we describe active living collagen implants with highly promising bone regenerative properties. Bioactivity of the implants is obtained through the protective and stabilizing layer-by-layer immobilization of a protein growth factor in association with a polysaccharide (chitosan), within the form of nanocontainers decorating the collagen nanofibers. All components of the implants are US FDA approved. From both in vitro and in vivo evaluations, the sophisticated strategy described here should enhance, at a reduced cost, the safety and efficacy of the therapeutic implants in terms of large bone defects repair compared with current simplistic approaches based on the soaking of the implants with protein growth factor.

Lineage-Specific Differences between the gp120 Inner Domain Layer 3 of Human Immunodeficiency Virus and That of Simian Immunodeficiency Virus

PubMed Central

Ding, Shilei; Medjahed, Halima; Prévost, Jérémie; Coutu, Mathieu; Xiang, Shi-Hua

2016-01-01

ABSTRACT Binding of human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) gp120 exterior envelope glycoprotein to CD4 triggers conformational changes in gp120 that promote its interaction with one of the chemokine receptors, usually CCR5, ultimately leading to gp41-mediated virus-cell membrane fusion and entry. We previously described that topological layers (layer 1, layer 2, and layer 3) in the gp120 inner domain contribute to gp120-trimer association in the unliganded state but also help secure CD4 binding. Relative to layer 1 of HIV-1 gp120, the SIVmac239 gp120 layer 1 plays a more prominent role in maintaining gp120-trimer association but is minimally involved in promoting CD4 binding, which could be explained by the existence of a well-conserved tryptophan at position 375 (Trp 375) in HIV-2/SIVsmm. In this study, we investigated the role of SIV layer 3 in viral entry, cell-to-cell fusion, and CD4 binding. We observed that a network of interactions involving some residues of the β8-α5 region in SIVmac239 layer 3 may contribute to CD4 binding by helping shape the nearby Phe 43 cavity, which directly contacts CD4. In summary, our results suggest that layer 3 in SIV has a greater impact on CD4 binding than in HIV-1. This work defines lineage-specific differences in layer 3 from HIV-1 and that from SIV. IMPORTANCE CD4-induced conformational changes in the gp120 inner domain involve rearrangements between three topological layers. While the role of layers 1 to 3 for HIV-1 and layers 1 and 2 for SIV on gp120 transition to the CD4-bound conformation has been reported, the role of SIV layer 3 remains unknown. Here we report that SIV layer 3 has a greater impact on CD4 binding than does layer 3 in HIV-1 gp120. This work defines lineage-specific differences in layer 3 from HIV-1 and SIV. PMID:27535053

Non-Linear Finite Element Modeling of THUNDER Piezoelectric Actuators

NASA Technical Reports Server (NTRS)

Taleghani, Barmac K.; Campbell, Joel F.

1999-01-01

A NASTRAN non-linear finite element model has been developed for predicting the dome heights of THUNDER (THin Layer UNimorph Ferroelectric DrivER) piezoelectric actuators. To analytically validate the finite element model, a comparison was made with a non-linear plate solution using Von Karmen's approximation. A 500 volt input was used to examine the actuator deformation. The NASTRAN finite element model was also compared with experimental results. Four groups of specimens were fabricated and tested. Four different input voltages, which included 120, 160, 200, and 240 Vp-p with a 0 volts offset, were used for this comparison.

The high-energy-density counterpropagating shear experiment and turbulent self-heating

DOE PAGES

Doss, F. W.; Fincke, J. R.; Loomis, E. N.; ...

2013-12-06

The counterpropagating shear experiment has previously demonstrated the ability to create regions of shockdriven shear, balanced symmetrically in pressure and experiencing minimal net drift. This allows for the creation of a high-Mach-number high-energy-density shear environment. New data from the counterpropagating shear campaign is presented, and both hydrocode modeling and theoretical analysis in the context of a Reynolds-averaged-Navier-Stokes model suggest turbulent dissipation of energy from the supersonic flow bounding the layer is a significant driver in its expansion. A theoretical minimum shear flow Mach number threshold is suggested for substantial thermal-turbulence coupling.

Direct reading of charge multipliers with a self-triggering CMOS analog chip with 105 k pixels at 50 μm pitch

NASA Astrophysics Data System (ADS)

Bellazzini, R.; Spandre, G.; Minuti, M.; Baldini, L.; Brez, A.; Cavalca, F.; Latronico, L.; Omodei, N.; Massai, M. M.; Sgro', C.; Costa, E.; Soffitta, P.; Krummenacher, F.; de Oliveira, R.

2006-10-01

We report on a large area (15×15 mm2), high channel density (470 pixel/mm2), self-triggering CMOS analog chip that we have developed as a pixelized charge collecting electrode of a Micropattern Gas Detector. This device represents a big step forward both in terms of size and performance, and is in fact the last version of three generations of custom ASICs of increasing complexity. The top metal layer of the CMOS pixel array is patterned in a matrix of 105,600 hexagonal pixels with a 50 μm pitch. Each pixel is directly connected to the underlying full electronics chain which has been realized in the remaining five metal and single poly-silicon layers of a 0.18 μm VLSI technology. The chip, which has customizable self-triggering capabilities, also includes a signal pre-processing function for the automatic localization of the event coordinates. Thanks to these advances it is possible to significantly reduce the read-out time and the data volume by limiting the signal output only to those pixels belonging to the region of interest. In addition to the reduced read-out time and data volume, the very small pixel area and the use of a deep sub-micron CMOS technology has allowed bringing the noise down to 50 electrons ENC. Results from in depth tests of this device when coupled to a fine pitch (50 μm on a triangular pattern) Gas Electron Multiplier are presented. It was found that matching the read-out and gas amplification pitch allows getting optimal results. The experimental detector response to polarized and unpolarized X-ray radiation when working with two gas mixtures and two different photon energies is shown and the application of this detector for Astronomical X-ray Polarimetry is discussed. Results from a full Monte-Carlo simulation for several galactic and extragalactic astronomical sources are also reported.

Ischemia Reperfusion Injury Triggers TNFα Induced-Necroptosis in Rat Retina.

PubMed

Kim, Cho Rong; Kim, Jie Hyun; Park, Hae-Young Lopilly; Park, Chan Kee

2017-05-01

A recent study revealed a novel form of cell death, termed necroptosis, or programmed necrosis. Previous research indicated that after ischemia-reperfusion (IR) injury to the retina, Tumor Necrosis Factor α (TNFα) is increased, which may activate necroptosis. This study observed macroglial cell activation, and in particular, astrocyte activation, after the release of TNFα and other necroptosis factors in the rat retina due to IR. IR was induced in the retinas of adult male Sprague-Dawley rats by increasing the intraocular pressure to 160 mmHg and then allowing reperfusion. In addition, to inhibit necroptosis, Nec-1 (necrostatin-1) was injected intravitreally after IR. Rats were sacrificed after reperfusion at 12 hours, 1, 3, and 5 days, and 1 and 2 weeks. Retinas from each time point were analyzed by immunohistochemistry (IHC) and Western blotting (WB) to identify the initiator of necroptosis, TNFα, the expression of necroptosis factors, such as receptor interacting protein (RIP) 1, 3, and inactive caspase 8, and Brn3a. Cell death in the IR-injured retinas was identified by cell counting. We found decreased retinal cell numbers in the inner and outer nuclear layers (INL and ONL), as well as in the ganglion cell layer (GCL). Increased glial cell activation was detected by using glial fibrillary acidic protein (GFAP) IHC. TNFα, RIP1, RIP3, and inactive caspase 8 were mainly expressed in the GCL after IR, as determined by IHC and WB. Nec-1 inhibited RIP1, a necroptosis factor, indicating protection against retinal cell loss after IR injury. We showed that IR injury triggered increases in both activation of astrocytes and the expression of TNFα. In addition, TNFα, which was activated by IR, triggered the release of necroptosis factors, particularly, in GCL. Inhibition of necroptosis using Nec-1 decreased the level of RIP1 and retinal cell loss in IR-injured retinas.

Lack of evidence of rotavirus-dependent molecular mimicry as a trigger of coeliac disease.

PubMed

Ziberna, F; De Lorenzo, G; Schiavon, V; Arnoldi, F; Quaglia, S; De Leo, L; Vatta, S; Martelossi, S; Burrone, O R; Ventura, A; Not, T

2016-12-01

New data suggest the involvement of rotavirus (RV) in triggering autoimmunity in coeliac disease (CD) by molecular mimicry between the human-transglutaminase protein and the dodecapeptide (260-271 aa) of the RV protein VP7 (pVP7). To assess the role of RV in the onset of CD, we measured anti-pVP7 antibodies in the sera of children with CD and of control groups. We analysed serum samples of 118 biopsy-proven CD patients and 46 patients with potential CD; 32 children with other gastrointestinal diseases; 107 no-CD children and 107 blood donors. Using enzyme-linked immunosorbent assay (ELISA) assay, we measured immunoglobulin (Ig)A-IgG antibodies against the synthetic peptides pVP7, the human transglutaminase-derived peptide (476-487 aa) which shows a homology with VP7 protein and a control peptide. The triple-layered RV particles (TLPs) containing the VP7 protein and the double-layered RV-particles (DLPs) lacking the VP7 protein were also used as antigens in ELISA assay. Antibody reactivity to the RV-TLPs was positive in 22 of 118 (18%) CD patients and in both paediatric (17 of 107, 16%) and adult (29 of 107, 27%) control groups, without showing a statistically significant difference among them (P = 0·6, P = 0·1). Biopsy-proven CD patients as well as the adult control group demonstrated a high positive antibody reactivity against both pVP7 (34 of 118, 29% CD patients; 66 of 107, 62% adult controls) and control synthetic peptides (35 of 118, 30% CD patients; 56 of 107, 52% adult controls), suggesting a non-specific response against RV pVP7. We show that children with CD do not have higher immune reactivity to RV, thus questioning the molecular mimicry mechanism as a triggering factor of CD. © 2016 British Society for Immunology.

The influence of anisotropy on preferential flow in landslides

NASA Astrophysics Data System (ADS)

Cristiano, Elena; Barontini, Stefano; Bogaard, Thom A.; Shao, Wei

2015-04-01

Infiltration is one of the most important landslides triggering mechanisms and it is controlled by the hydraulic characteristics of the soil, which depends on the degree of saturation, the existence of preferential flow paths and by anisotropy. Many soils, indeed, exhibit a certain degree of anisotropy due to the stratification associated with soil forming process. Recently, various authors investigated the effect of rainfall in layered soils and its effect on rainfall triggered landslides by means of experimental, conceptual, numerical and theoretical approaches. However, the combined effect of anisotropy and preferential flow on infiltration process and related to rainfall induced landslides has, according to the authors best knowledge, not been studied yet. Aiming at better understanding the soil hydrological processes which take place during an infiltration process, the stability of a synthetic hill slope is numerically investigated. The geometry we considered for the model is a slope with two different layers: the upper soil layer consists of sandy loam, while the lower soil layer is made out of clay. The geometry was studied using both a single permeability and a dual permeability model. In the first case the hydraulic conductivity at saturation was considered isotropic, equal in all directions. Then the vertical component of the hydraulic conductivity tensor at saturation was reduced, while in the third scenario the horizontal component was reduced. In this way the anisotropy effects on both the principal directions were studied. In the dual permeability model, the influence of the anisotropy was considered only in the preferential flow domain, and the hydraulic conductivity at saturation of the soil matrix domain was defined as being isotropic. In order to evaluate also the effects of rainfall intensity on the slope, two different rainfall events were studied: a low intensity rainfall with a long time duration (2 mmh-1,150 h) and an high intensity rainfall with a short duration (20 mmh-1,15 h). The results show that the anisotropy facilitates the saturation process in the slope and that the vertical component of the soil water flow is set especially in the soil matrix domain, while the lateral component dominates in the preferential flow domain. In some scenarios the patterns of the water content in the unsaturated soil layers suggest the possibility of the onset of a perched water table.

A role of NF-E2 in chronic inflammation and clonal evolution in essential thrombocythemia, polycythemia vera and myelofibrosis?

PubMed

Hasselbalch, Hans C

2014-02-01

A novel murine model for myeloproliferative neoplasms (MPNs) generated by overexpression of the transcription factor NF-E2 has recently been described. Sustained overexpression of NF-E2 in this model induced myeloid expansion with anemia, leukocytosis and thrombocytosis. Herein, it is debated if NF-E2 overexpression also might have induced a sustained state of in vivo leukocyte and platelet activation with chronic and self-perpetuating production of inflammatory products from activated leukocytes and platelets. If so, this novel murine model also may excellently describe the deleterious impact of sustained chronic NF-E2 overexpression during uncontrolled chronic inflammation upon the hematopoietic system--the development of clonal myeloproliferation. Accordingly, this novel murine model may also have delivered the proof of concept of chronic inflammation as a trigger and driver of clonal evolution in MPNs. Copyright © 2013 Elsevier Ltd. All rights reserved.

Distant storms as drivers of environmental change at Pacific atolls.

PubMed

Gardner, Jonathan P A; Garton, David W; Collen, John D; Zwartz, Daniel

2014-01-01

The central Pacific Ocean with its many low lying islands and atolls is under threat from sea level rise and increased storm activity. Here, we illustrate how increasing frequency and severity of large scale storm events associated with global climate change may be particularly profound at the local scale for human populations that rely on lagoon systems for provision of a variety of goods and services. In August 2011 a storm originating in the Southern Ocean caused a large amplitude ocean swell to move northward through the Pacific Ocean. Its arrival at Palmyra Atoll coincided with transient elevated sea surface height and triggered turnover of the lagoon water column. This storm-induced change to the lagoon reflects long distance connectivity with propagated wave energy from the Southern Ocean and illustrates the increasing threats generated by climate change that are faced by human populations on most low-lying Pacific islands and atolls.

Stellar flare oscillations: evidence for oscillatory reconnection and evolution of MHD modes

NASA Astrophysics Data System (ADS)

Doyle, J. G.; Shetye, J.; Antonova, A. E.; Kolotkov, D. Y.; Srivastava, A. K.; Stangalini, M.; Gupta, G. R.; Avramova, A.; Mathioudakis, M.

2018-04-01

Here, we report on the detection of a range of quasi-periodic pulsations (20-120 s; QPPs) observed during flaring activity of several magnetically active dMe stars, namely AF Psc, CR Dra, GJ 3685A, Gl 65, SDSS J084425.9+513830, and SDSS J144738.47+035312.1 in the GALEX NUV filter. Based on a solar analogy, this work suggests that many of these flares may be triggered by external drivers creating a periodic reconnection in the flare current sheet or an impulsive energy release giving rise to an avalanche of periodic bursts that occur at time intervals that correspond to the detected periods, thus generating QPPs in their rising and peak phases. Some of these flares also show fast QPPs in their decay phase, indicating the presence of fast sausage mode oscillations either driven externally by periodic reconnection or intrinsically in the post-flare loop system during the flare energy release.

Distant Storms as Drivers of Environmental Change at Pacific Atolls

PubMed Central

Gardner, Jonathan P. A.; Garton, David W.; Collen, John D.; Zwartz, Daniel

2014-01-01

The central Pacific Ocean with its many low lying islands and atolls is under threat from sea level rise and increased storm activity. Here, we illustrate how increasing frequency and severity of large scale storm events associated with global climate change may be particularly profound at the local scale for human populations that rely on lagoon systems for provision of a variety of goods and services. In August 2011 a storm originating in the Southern Ocean caused a large amplitude ocean swell to move northward through the Pacific Ocean. Its arrival at Palmyra Atoll coincided with transient elevated sea surface height and triggered turnover of the lagoon water column. This storm-induced change to the lagoon reflects long distance connectivity with propagated wave energy from the Southern Ocean and illustrates the increasing threats generated by climate change that are faced by human populations on most low-lying Pacific islands and atolls. PMID:24498232

Gut Microbiota as a Driver of Inflammation in Nonalcoholic Fatty Liver Disease

PubMed Central

Ianiro, Gianluca; Simonelli, Claudia; Newton, Estelle E.

2018-01-01

The prevalence of nonalcoholic fatty liver disease and the consequent burden of metabolic syndrome have increased in recent years. Although the pathogenesis of nonalcoholic fatty liver disease is not completely understood, it is thought to be the hepatic manifestation of the dysregulation of insulin-dependent pathways leading to insulin resistance and adipose tissue accumulation in the liver. Recently, the gut-liver axis has been proposed as a key player in the pathogenesis of NAFLD, as the passage of bacteria-derived products into the portal circulation could lead to a trigger of innate immunity, which in turn leads to liver inflammation. Additionally, higher prevalence of intestinal dysbiosis, larger production of endogenous ethanol, and higher prevalence of increased intestinal permeability and bacterial translocation were found in patients with liver injury. In this review, we describe the role of intestinal dysbiosis in the activation of the inflammatory cascade in NAFLD. PMID:29563854

Disease prevention--should we target obesity or sedentary lifestyle?

PubMed

Charansonney, Olivier L; Després, Jean-Pierre

2010-08-01

Obesity is a major health challenge facing the modern world. Some evidence points to obesity itself as the main driver of premature mortality. We propose that this view is oversimplified. For example, high levels of physical activity and cardiorespiratory fitness are associated with lower mortality, even in those who are overweight or obese. To address this issue, we combine epidemiological and physiological evidence in a new paradigm that integrates excess calorie intake, sedentary behavior, and a maladaptive response to stress. Human physiology is optimized to allow large distances to be covered on foot every day in order to find enough food to sustain brain metabolism. Furthermore, when the body is immobilized by an injury, it triggers efficient life-saving metabolic and inflammatory responses. Both these critical adaptations are, however, confounded by a sedentary lifestyle. The implications of these issues for clinical trial design and epidemiologic data analysis are discussed in this article.

Mitochondria in the Aging Muscles of Flies and Mice: New Perspectives for Old Characters

PubMed Central

2016-01-01

Sarcopenia is the loss of muscle mass accompanied by a decrease in muscle strength and resistance and is the main cause of disability among the elderly. Muscle loss begins long before there is any clear physical impact in the senior adult. Despite all this, the molecular mechanisms underlying muscle aging are far from being understood. Recent studies have identified that not only mitochondrial metabolic dysfunction but also mitochondrial dynamics and mitochondrial calcium uptake could be involved in the degeneration of skeletal muscle mass. Mitochondrial homeostasis influences muscle quality which, in turn, could play a triggering role in signaling of systemic aging. Thus, it has become apparent that mitochondrial status in muscle cells could be a driver of whole body physiology and organismal aging. In the present review, we discuss the existing evidence for the mitochondria related mechanisms underlying the appearance of muscle aging and sarcopenia in flies and mice. PMID:27630760

Mitochondria in the Aging Muscles of Flies and Mice: New Perspectives for Old Characters.

PubMed

Del Campo, Andrea; Jaimovich, Enrique; Tevy, Maria Florencia

2016-01-01

Sarcopenia is the loss of muscle mass accompanied by a decrease in muscle strength and resistance and is the main cause of disability among the elderly. Muscle loss begins long before there is any clear physical impact in the senior adult. Despite all this, the molecular mechanisms underlying muscle aging are far from being understood. Recent studies have identified that not only mitochondrial metabolic dysfunction but also mitochondrial dynamics and mitochondrial calcium uptake could be involved in the degeneration of skeletal muscle mass. Mitochondrial homeostasis influences muscle quality which, in turn, could play a triggering role in signaling of systemic aging. Thus, it has become apparent that mitochondrial status in muscle cells could be a driver of whole body physiology and organismal aging. In the present review, we discuss the existing evidence for the mitochondria related mechanisms underlying the appearance of muscle aging and sarcopenia in flies and mice.

Macrofossil evidence for a rapid and severe Cretaceous-Paleogene mass extinction in Antarctica.

PubMed

Witts, James D; Whittle, Rowan J; Wignall, Paul B; Crame, J Alistair; Francis, Jane E; Newton, Robert J; Bowman, Vanessa C

2016-05-26

Debate continues about the nature of the Cretaceous-Paleogene (K-Pg) mass extinction event. An abrupt crisis triggered by a bolide impact contrasts with ideas of a more gradual extinction involving flood volcanism or climatic changes. Evidence from high latitudes has also been used to suggest that the severity of the extinction decreased from low latitudes towards the poles. Here we present a record of the K-Pg extinction based on extensive assemblages of marine macrofossils (primarily new data from benthic molluscs) from a highly expanded Cretaceous-Paleogene succession: the López de Bertodano Formation of Seymour Island, Antarctica. We show that the extinction was rapid and severe in Antarctica, with no significant biotic decline during the latest Cretaceous, contrary to previous studies. These data are consistent with a catastrophic driver for the extinction, such as bolide impact, rather than a significant contribution from Deccan Traps volcanism during the late Maastrichtian.

Macrofossil evidence for a rapid and severe Cretaceous-Paleogene mass extinction in Antarctica

NASA Astrophysics Data System (ADS)

Witts, James D.; Whittle, Rowan J.; Wignall, Paul B.; Crame, J. Alistair; Francis, Jane E.; Newton, Robert J.; Bowman, Vanessa C.

2016-05-01

Debate continues about the nature of the Cretaceous-Paleogene (K-Pg) mass extinction event. An abrupt crisis triggered by a bolide impact contrasts with ideas of a more gradual extinction involving flood volcanism or climatic changes. Evidence from high latitudes has also been used to suggest that the severity of the extinction decreased from low latitudes towards the poles. Here we present a record of the K-Pg extinction based on extensive assemblages of marine macrofossils (primarily new data from benthic molluscs) from a highly expanded Cretaceous-Paleogene succession: the López de Bertodano Formation of Seymour Island, Antarctica. We show that the extinction was rapid and severe in Antarctica, with no significant biotic decline during the latest Cretaceous, contrary to previous studies. These data are consistent with a catastrophic driver for the extinction, such as bolide impact, rather than a significant contribution from Deccan Traps volcanism during the late Maastrichtian.

Macrofossil evidence for a rapid and severe Cretaceous–Paleogene mass extinction in Antarctica

PubMed Central

Witts, James D.; Whittle, Rowan J.; Wignall, Paul B.; Crame, J. Alistair; Francis, Jane E.; Newton, Robert J.; Bowman, Vanessa C.

2016-01-01

Debate continues about the nature of the Cretaceous–Paleogene (K–Pg) mass extinction event. An abrupt crisis triggered by a bolide impact contrasts with ideas of a more gradual extinction involving flood volcanism or climatic changes. Evidence from high latitudes has also been used to suggest that the severity of the extinction decreased from low latitudes towards the poles. Here we present a record of the K–Pg extinction based on extensive assemblages of marine macrofossils (primarily new data from benthic molluscs) from a highly expanded Cretaceous–Paleogene succession: the López de Bertodano Formation of Seymour Island, Antarctica. We show that the extinction was rapid and severe in Antarctica, with no significant biotic decline during the latest Cretaceous, contrary to previous studies. These data are consistent with a catastrophic driver for the extinction, such as bolide impact, rather than a significant contribution from Deccan Traps volcanism during the late Maastrichtian. PMID:27226414

Inter-Cellular Forces Orchestrate Contact Inhibition of Locomotion

PubMed Central

Davis, John R.; Luchici, Andrei; Mosis, Fuad; Thackery, James; Salazar, Jesus A.; Mao, Yanlan; Dunn, Graham A.; Betz, Timo; Miodownik, Mark; Stramer, Brian M.

2015-01-01

Summary Contact inhibition of locomotion (CIL) is a multifaceted process that causes many cell types to repel each other upon collision. During development, this seemingly uncoordinated reaction is a critical driver of cellular dispersion within embryonic tissues. Here, we show that Drosophila hemocytes require a precisely orchestrated CIL response for their developmental dispersal. Hemocyte collision and subsequent repulsion involves a stereotyped sequence of kinematic stages that are modulated by global changes in cytoskeletal dynamics. Tracking actin retrograde flow within hemocytes in vivo reveals synchronous reorganization of colliding actin networks through engagement of an inter-cellular adhesion. This inter-cellular actin-clutch leads to a subsequent build-up in lamellar tension, triggering the development of a transient stress fiber, which orchestrates cellular repulsion. Our findings reveal that the physical coupling of the flowing actin networks during CIL acts as a mechanotransducer, allowing cells to haptically sense each other and coordinate their behaviors. PMID:25799385

Special report: Occlusive cuff controller

NASA Technical Reports Server (NTRS)

Baker, J. T.

1975-01-01

A mechanical occlusive cuff controller suitable for blood flow experiments in space shuttle flights is described. The device requires 115 volt ac power and a pressurized gas source. Two occluding cuff pressures (30 and 50 mmHg) are selectable by a switch on the front panel. A screw driver adjustment allows accurate cuff pressurization levels for under or oversized limbs. Two pressurization cycles (20 second and 2 minutes) can be selected by a front panel switch. Adjustment of the timing cycles is also available through the front panel. A pushbutton hand switch allows remote start of the cuff inflation cycle. A stop/reset switch permits early termination of the cycle and disabling of the controller to prevent inadvertent reactivation. Pressure in the cuff is monitored by a differential aneroid barometer. In addition, an electrocardiogram trigger circuit permits the initiation of the pressurization cycle by an externally supplied ECG cycle.

Alcohol reduces aversion to ambiguity.

PubMed

Tyszka, Tadeusz; Macko, Anna; Stańczak, Maciej

2014-01-01

Several years ago, Cohen et al. (1958) demonstrated that under the influence of alcohol drivers became more risk prone, although their risk perception remained unchanged. Research shows that ambiguity aversion is to some extent positively correlated with risk aversion, though not very highly (Camerer and Weber, 1992). The question addressed by the present research is whether alcohol reduces ambiguity aversion. Our research was conducted in a natural setting (a restaurant bar), where customers with differing levels of alcohol intoxication were offered a choice between a risky and an ambiguous lottery. We found that alcohol reduced ambiguity aversion and that the effect occurred in men but not women. We interpret these findings in terms of the risk-as-value hypothesis, according to which, people in Western culture tend to value risk, and suggest that alcohol consumption triggers adherence to socially and culturally valued patterns of conduct different for men and women.

Evidence for ice-ocean albedo feedback in the Arctic Ocean shifting to a seasonal ice zone.

PubMed

Kashiwase, Haruhiko; Ohshima, Kay I; Nihashi, Sohey; Eicken, Hajo

2017-08-15

Ice-albedo feedback due to the albedo contrast between water and ice is a major factor in seasonal sea ice retreat, and has received increasing attention with the Arctic Ocean shifting to a seasonal ice cover. However, quantitative evaluation of such feedbacks is still insufficient. Here we provide quantitative evidence that heat input through the open water fraction is the primary driver of seasonal and interannual variations in Arctic sea ice retreat. Analyses of satellite data (1979-2014) and a simplified ice-upper ocean coupled model reveal that divergent ice motion in the early melt season triggers large-scale feedback which subsequently amplifies summer sea ice anomalies. The magnitude of divergence controlling the feedback has doubled since 2000 due to a more mobile ice cover, which can partly explain the recent drastic ice reduction in the Arctic Ocean.

Upgrading the ATLAS Tile Calorimeter Electronics

NASA Astrophysics Data System (ADS)

Carrió, Fernando

2013-11-01

This work summarizes the status of the on-detector and off-detector electronics developments for the Phase 2 Upgrade of the ATLAS Tile Calorimeter at the LHC scheduled around 2022. A demonstrator prototype for a slice of the calorimeter including most of the new electronics is planned to be installed in ATLAS in the middle of 2014 during the first Long Shutdown. For the on-detector readout, three different front-end boards (FEB) alternatives are being studied: a new version of the 3-in-1 card, the QIE chip and a dedicated ASIC called FATALIC. The Main Board will provide communication and control to the FEBs and the Daughter Board will transmit the digitized data to the off-detector electronics in the counting room, where the super Read-Out Driver (sROD) will perform processing tasks on them and will be the interface to the trigger levels 0, 1 and 2.

Parameterization of Rocket Dust Storms on Mars in the LMD Martian GCM: Modeling Details and Validation

NASA Astrophysics Data System (ADS)

Wang, Chao; Forget, François; Bertrand, Tanguy; Spiga, Aymeric; Millour, Ehouarn; Navarro, Thomas

2018-04-01

The origin of the detached dust layers observed by the Mars Climate Sounder aboard the Mars Reconnaissance Orbiter is still debated. Spiga et al. (2013, https://doi.org/10.1002/jgre.20046) revealed that deep mesoscale convective "rocket dust storms" are likely to play an important role in forming these dust layers. To investigate how the detached dust layers are generated by this mesoscale phenomenon and subsequently evolve at larger scales, a parameterization of rocket dust storms to represent the mesoscale dust convection is designed and included into the Laboratoire de Météorologie Dynamique (LMD) Martian Global Climate Model (GCM). The new parameterization allows dust particles in the GCM to be transported to higher altitudes than in traditional GCMs. Combined with the horizontal transport by large-scale winds, the dust particles spread out and form detached dust layers. During the Martian dusty seasons, the LMD GCM with the new parameterization is able to form detached dust layers. The formation, evolution, and decay of the simulated dust layers are largely in agreement with the Mars Climate Sounder observations. This suggests that mesoscale rocket dust storms are among the key factors to explain the observed detached dust layers on Mars. However, the detached dust layers remain absent in the GCM during the clear seasons, even with the new parameterization. This implies that other relevant atmospheric processes, operating when no dust storms are occurring, are needed to explain the Martian detached dust layers. More observations of local dust storms could improve the ad hoc aspects of this parameterization, such as the trigger and timing of dust injection.

Thermal Rayleigh-Marangoni convection in a three-layer liquid-metal-battery model.

PubMed

Köllner, Thomas; Boeck, Thomas; Schumacher, Jörg

2017-05-01

The combined effects of buoyancy-driven Rayleigh-Bénard convection (RC) and surface tension-driven Marangoni convection (MC) are studied in a triple-layer configuration which serves as a simplified model for a liquid metal battery (LMB). The three-layer model consists of a liquid metal alloy cathode, a molten salt separation layer, and a liquid metal anode at the top. Convection is triggered by the temperature gradient between the hot electrolyte and the colder electrodes, which is a consequence of the release of resistive heat during operation. We present a linear stability analysis of the state of pure thermal conduction in combination with three-dimensional direct numerical simulations of the nonlinear turbulent evolution on the basis of a pseudospectral method. Five different modes of convection are identified in the configuration, which are partly coupled to each other: RC in the upper electrode, RC with internal heating in the molten salt layer, and MC at both interfaces between molten salt and electrode as well as anticonvection in the middle layer and lower electrode. The linear stability analysis confirms that the additional Marangoni effect in the present setup increases the growth rates of the linearly unstable modes, i.e., Marangoni and Rayleigh-Bénard instability act together in the molten salt layer. The critical Grashof and Marangoni numbers decrease with increasing middle layer thickness. The calculated thresholds for the onset of convection are found for realistic current densities of laboratory-sized LMBs. The global turbulent heat transfer follows scaling predictions for internally heated RC. The global turbulent momentum transfer is comparable with turbulent convection in the classical Rayleigh-Bénard case. In summary, our studies show that incorporating Marangoni effects generates smaller flow structures, alters the velocity magnitudes, and enhances the turbulent heat transfer across the triple-layer configuration.

Thermal Rayleigh-Marangoni convection in a three-layer liquid-metal-battery model

NASA Astrophysics Data System (ADS)

Köllner, Thomas; Boeck, Thomas; Schumacher, Jörg

2017-05-01

The combined effects of buoyancy-driven Rayleigh-Bénard convection (RC) and surface tension-driven Marangoni convection (MC) are studied in a triple-layer configuration which serves as a simplified model for a liquid metal battery (LMB). The three-layer model consists of a liquid metal alloy cathode, a molten salt separation layer, and a liquid metal anode at the top. Convection is triggered by the temperature gradient between the hot electrolyte and the colder electrodes, which is a consequence of the release of resistive heat during operation. We present a linear stability analysis of the state of pure thermal conduction in combination with three-dimensional direct numerical simulations of the nonlinear turbulent evolution on the basis of a pseudospectral method. Five different modes of convection are identified in the configuration, which are partly coupled to each other: RC in the upper electrode, RC with internal heating in the molten salt layer, and MC at both interfaces between molten salt and electrode as well as anticonvection in the middle layer and lower electrode. The linear stability analysis confirms that the additional Marangoni effect in the present setup increases the growth rates of the linearly unstable modes, i.e., Marangoni and Rayleigh-Bénard instability act together in the molten salt layer. The critical Grashof and Marangoni numbers decrease with increasing middle layer thickness. The calculated thresholds for the onset of convection are found for realistic current densities of laboratory-sized LMBs. The global turbulent heat transfer follows scaling predictions for internally heated RC. The global turbulent momentum transfer is comparable with turbulent convection in the classical Rayleigh-Bénard case. In summary, our studies show that incorporating Marangoni effects generates smaller flow structures, alters the velocity magnitudes, and enhances the turbulent heat transfer across the triple-layer configuration.

Unexpected winter phytoplankton blooms in the North Atlantic subpolar gyre

NASA Astrophysics Data System (ADS)

Lacour, L.; Ardyna, M.; Stec, K. F.; Claustre, H.; Prieur, L.; Poteau, A.; D'Alcala, M. Ribera; Iudicone, D.

2017-11-01

In mid- and high-latitude oceans, winter surface cooling and strong winds drive turbulent mixing that carries phytoplankton to depths of several hundred metres, well below the sunlit layer. This downward mixing, in combination with low solar radiation, drastically limits phytoplankton growth during the winter, especially that of the diatoms and other species that are involved in seeding the spring bloom. Here we present observational evidence for widespread winter phytoplankton blooms in a large part of the North Atlantic subpolar gyre from autonomous profiling floats equipped with biogeochemical sensors. These blooms were triggered by intermittent restratification of the mixed layer when mixed-layer eddies led to a horizontal transport of lighter water over denser layers. Combining a bio-optical index with complementary chemotaxonomic and modelling approaches, we show that these restratification events increase phytoplankton residence time in the sunlight zone, resulting in greater light interception and the emergence of winter blooms. Restratification also caused a phytoplankton community shift from pico- and nanophytoplankton to phototrophic diatoms. We conclude that transient winter blooms can maintain active diatom populations throughout the winter months, directly seeding the spring bloom and potentially making a significant contribution to over-winter carbon export.

Balloon-borne measurements of aerosol, condensation nuclei, and cloud particles in the stratosphere at McMurdo Station, Antarctica, during the spring of 1987

NASA Technical Reports Server (NTRS)

Hofmann, D. J.; Rosen, J. M.; Harder, J. W.; Hereford, J. V.

1989-01-01

Measurements of the vertical profile of particles with condensation nuclei counters and eight channel aerosol detectors at McMurdo Station, Antarctica, in 1987 verified observations made in 1986 concerning the absence of upwelling in the polar vortex and the presence of a condensation nuclei layer in conjunction with the ozone hole region. New observations of a bimodal aerosol size distribution, consisting of a large-particle mode mixed in with the small-particle sulfate mode, at temperatures below -79 C are consistent with the presence of nitric acid-water particles at low concentrations. Higher concentrations of large particles were observed in association with nacreous clouds. An unusual particle layer which contained enhanced concentrations of both the small-particle (sulfate) mode and the large-particle (nitric acid) mode was detected at temperatures below -85 C, suggesting simultaneous nucleation and growth phenomena. The vortex condensation nuclei layer was observed to form at the same time as the ozone hole, indicating that formation of the layer is triggered by photochemical processes and may be important in controlling ozone depletion above 22 km.

A global geochemical model for the evolution of the mantle

NASA Technical Reports Server (NTRS)

Anderson, D. L.

1979-01-01

It is proposed that the upper mantle transition region, 220 to 670 km, is composed of eclogite which has been derived from primitive mantle by about 20 percent partial melting and that this is the source and sink of oceanic crust. The remainder of the upper mantle is garnet peridotite which is the source of continental basalts and hotspot magmas. This region is enriched in incompatible elements by hydrous and CO2 rich metasomatic fluids which have depleted the underlying layers in the L.I.L. elements and L.R.E.E. The volatiles make this a low-velocity, high attenuation, low viscosity region. The eclogite layer is internally heated and its controls the convection pattern in the upper mantle. Plate tectonics is intermittent. The continental thermal anomaly at a depth of 150-220 km triggers kimberlite and carbonatite activity, alkali and flood basalt volcanism, vertical tectonics and continental breakup. Hot spots remain active after the continents leave and build the oceanic islands. Mantle plumes rise from a depth of about 220 km. Midocean ridge basalts rise from the depleted layer below this depth. Material from this layer can also be displaced upwards by subducted oceanic lithosphere to form back-arc basins.

Microporous polymeric 3D scaffolds templated by the layer-by-layer self-assembly.

PubMed

Paulraj, Thomas; Feoktistova, Natalia; Velk, Natalia; Uhlig, Katja; Duschl, Claus; Volodkin, Dmitry

2014-08-01

Polymeric scaffolds serve as valuable supports for biological cells since they offer essential features for guiding cellular organization and tissue development. The main challenges for scaffold fabrication are i) to tune an internal structure and ii) to load bio-molecules such as growth factors and control their local concentration and distribution. Here, a new approach for the design of hollow polymeric scaffolds using porous CaCO3 particles (cores) as templates is presented. The cores packed into a microfluidic channel are coated with polymers employing the layer-by-layer (LbL) technique. Subsequent core elimination at mild conditions results in formation of the scaffold composed of interconnected hollow polymer microspheres. The size of the cores determines the feature dimensions and, as a consequence, governs cellular adhesion: for 3T3 fibroblasts an optimal microsphere size is 12 μm. By making use of the carrier properties of the porous CaCO3 cores, the microspheres are loaded with BSA as a model protein. The scaffolds developed here may also be well suited for the localized release of bio-molecules using external triggers such as IR-light. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Electrolyte-stimulated biphasic dissolution profile and stability enhancement for tablets containing drug-polyelectrolyte complexes.

PubMed

Kindermann, Christoph; Matthée, Karin; Sievert, Frank; Breitkreutz, Jörg

2012-10-01

Recently introduced drug-polyelectrolyte complexes prepared by hot-melt extrusion should be processed to solid dosage forms with tailor-made release properties. Their potential of stability enhancement should be investigated. Milled hot-melt extruded naproxen-EUDRAGIT® E PO polyelectrolyte complexes were subsequently processed to double-layer tablets with varying complex loadings on a rotary-die press. Physicochemical interactions were studied under ICH guideline conditions and using the Gordon-Taylor equation. Sorption and desorption were determined to investigate the influence of moisture and temperature on the complex and related to stability tests under accelerated conditions. Naproxen release from the drug-polyelectrolyte complex is triggered by electrolyte concentration. Depending on the complex loading, phosphate buffer pH 6.8 stimulated a biphasic dissolution profile of the produced double-layer tablets: immediate release from the first layer with 65% loading and prolonged release from the second layer within 24 h (98.5% loading). XRPD patterns proved pseudopolymorphism for tablets containing the pure drug under common storage conditions whereas the drug-complex was stable in the amorphous state. Drug-polyelectrolyte complexes enable tailor-made dissolution profiles of solid dosage forms by electrolyte stimulation and increase stability under common storage conditions.

The concept of self-organizing systems. Why bother?

NASA Astrophysics Data System (ADS)

Elverfeldt, Kirsten v.; Embleton-Hamann, Christine; Slaymaker, Olav

2016-04-01

Complexity theory and the concept of self-organizing systems provide a rather challenging conceptual framework for explaining earth systems change. Self-organization - understood as the aggregate processes internal to an environmental system that lead to a distinctive spatial or temporal organization - reduces the possibility of implicating a specific process as being causal, and it poses some restrictions on the idea that external drivers cause a system to change. The concept of self-organizing systems suggests that many phenomena result from an orchestration of different mechanisms, so that no causal role can be assigned to an individual factor or process. The idea that system change can be due to system-internal processes of self-organization thus proves a huge challenge to earth system research, especially in the context of global environmental change. In order to understand the concept's implications for the Earth Sciences, we need to know the characteristics of self-organizing systems and how to discern self-organizing systems. Within the talk, we aim firstly at characterizing self-organizing systems, and secondly at highlighting the advantages and difficulties of the concept within earth system sciences. The presentation concludes that: - The concept of self-organizing systems proves especially fruitful for small-scale earth surface systems. Beach cusps and patterned ground are only two of several other prime examples of self-organizing earth surface systems. They display characteristics of self-organization like (i) system-wide order from local interactions, (ii) symmetry breaking, (iii) distributed control, (iv) robustness and resilience, (v) nonlinearity and feedbacks, (vi) organizational closure, (vii) adaptation, and (viii) variation and selection. - It is comparatively easy to discern self-organization in small-scale systems, but to adapt the concept to larger scale systems relevant to global environmental change research is more difficult: Self-organizing systems seem to form nested hierarchies, and on different hierarchical levels self-organizing and externally driven subsystems might occur simultaneously. - Traditional geomorphological concepts such as sensitivity to change, and intrinsic or extrinsic thresholds are compatible with the concept of self-organizing system, and these concepts are even enriched in their explanatory power when viewed in the larger framework of self-organization. The conceptual step to acknowledge self-organizing system change within earth system sciences thus can be regarded as relatively small. The concept of self-organization suggests a change of focus for earth system change research: a shift from input-output relations toward the inner organization of systems, since external controls rather limit the degrees of freedom of a system instead of triggering changes. Many systems might in fact be rather autonomous, and the specific and observable external trigger might be less important than the intrinsic system state. Hence, neither gradual nor catastrophic system changes necessarily need an external driver. The concept of self-organization provides important caveats to generally attributing environmental change to external drivers, and it encourages a frank admission of ignorance in the face of complexity.

Non-methane hydrocarbons in the atmosphere of Mexico City: Results of the 2012 ozone-season campaign

NASA Astrophysics Data System (ADS)

Jaimes-Palomera, Mónica; Retama, Armando; Elias-Castro, Gabriel; Neria-Hernández, Angélica; Rivera-Hernández, Olivia; Velasco, Erik

2016-05-01

With the aim to strengthen the verification capabilities of the local air quality management, the air quality monitoring network of Mexico City has started the monitoring of selected non-methane hydrocarbons (NMHCs). Previous information on the NMHC characterization had been obtained through individual studies and comprehensive intensive field campaigns, in both cases restricted to sampling periods of short duration. This new initiative will address the NMHC pollution problem during longer monitoring periods and provide robust information to evaluate the effectiveness of new control measures. The article introduces the design of the monitoring network and presents results from the first campaign carried out during the first six months of 2012 covering the ozone-season (Mar-May). Using as reference data collected in 2003, results show reductions during the morning rush hour (6-9 h) in the mixing ratios of light alkanes associated with the consumption and distribution of liquefied petroleum gas and aromatic compounds related with the evaporation of fossil fuels and solvents, in contrast to olefins from vehicular traffic. The increase in mixing ratios of reactive olefins is of relevance to understand the moderate success in the ozone and fine aerosols abatement in recent years in comparison to other criteria pollutants. In the case of isoprene, the typical afternoon peak triggered by biogenic emissions was clearly observed for the first time within the city. The diurnal profiles of the monitored compounds are analyzed in terms of the energy balance throughout the day as a surrogate of the boundary layer evolution. Particular features of the diurnal profiles and correlation between individual NMHCs and carbon monoxide are used to investigate the influence of specific emission sources. The results discussed here highlight the importance of monitoring NMHCs to better understand the drivers and impacts of air pollution in large cities like Mexico City.

Saving the injured: Rescue behavior in the termite-hunting ant Megaponera analis.

PubMed

Frank, Erik Thomas; Schmitt, Thomas; Hovestadt, Thomas; Mitesser, Oliver; Stiegler, Jonas; Linsenmair, Karl Eduard

2017-04-01

Predators of highly defensive prey likely develop cost-reducing adaptations. The ant Megaponera analis is a specialized termite predator, solely raiding termites of the subfamily Macrotermitinae (in this study, mostly colonies of Pseudocanthotermes sp.) at their foraging sites. The evolutionary arms race between termites and ants led to various defensive mechanisms in termites (for example, a caste specialized in fighting predators). Because M. analis incurs high injury/mortality risks when preying on termites, some risk-mitigating adaptations seem likely to have evolved. We show that a unique rescue behavior in M. analis , consisting of injured nestmates being carried back to the nest, reduces combat mortality. After a fight, injured ants are carried back by their nestmates; these ants have usually lost an extremity or have termites clinging to them and are able to recover within the nest. Injured ants that are forced experimentally to return without help, die in 32% of the cases. Behavioral experiments show that two compounds, dimethyl disulfide and dimethyl trisulfide, present in the mandibular gland reservoirs, trigger the rescue behavior. A model accounting for this rescue behavior identifies the drivers favoring its evolution and estimates that rescuing enables maintenance of a 28.7% larger colony size. Our results are the first to explore experimentally the adaptive value of this form of rescue behavior focused on injured nestmates in social insects and help us to identify evolutionary drivers responsible for this type of behavior to evolve in animals.

Saving the injured: Rescue behavior in the termite-hunting ant Megaponera analis

PubMed Central

Frank, Erik Thomas; Schmitt, Thomas; Hovestadt, Thomas; Mitesser, Oliver; Stiegler, Jonas; Linsenmair, Karl Eduard

2017-01-01

Predators of highly defensive prey likely develop cost-reducing adaptations. The ant Megaponera analis is a specialized termite predator, solely raiding termites of the subfamily Macrotermitinae (in this study, mostly colonies of Pseudocanthotermes sp.) at their foraging sites. The evolutionary arms race between termites and ants led to various defensive mechanisms in termites (for example, a caste specialized in fighting predators). Because M. analis incurs high injury/mortality risks when preying on termites, some risk-mitigating adaptations seem likely to have evolved. We show that a unique rescue behavior in M. analis, consisting of injured nestmates being carried back to the nest, reduces combat mortality. After a fight, injured ants are carried back by their nestmates; these ants have usually lost an extremity or have termites clinging to them and are able to recover within the nest. Injured ants that are forced experimentally to return without help, die in 32% of the cases. Behavioral experiments show that two compounds, dimethyl disulfide and dimethyl trisulfide, present in the mandibular gland reservoirs, trigger the rescue behavior. A model accounting for this rescue behavior identifies the drivers favoring its evolution and estimates that rescuing enables maintenance of a 28.7% larger colony size. Our results are the first to explore experimentally the adaptive value of this form of rescue behavior focused on injured nestmates in social insects and help us to identify evolutionary drivers responsible for this type of behavior to evolve in animals. PMID:28439543