Sample records for two three four

  1. Proof of Monogamy of non-local correlations in three and four qubit states

    NASA Astrophysics Data System (ADS)

    Sharma, Santosh Shelly; Sharma, Naresh Kumar

    2015-03-01

    Recently, we used the process of selective construction of invariants to obtain physically meaningful polynomial invariants for three and four qubit pure states. In this article, we report the exact relations between the concurrence of a two qubit reduced state and corresponding three or four qubit pure state invariants. Firstly, we obtain an analytical expression for concurrence of a given mixed state of two qubits in terms of determinants of negativity fonts in the three or four qubit pure state. For three qubits, a comparison with three tangle and squared negativity expressed in terms of determinants of negativity fonts leads to three relations. These three conditions satisfied by the two-way and three-way correlations sum together and lead to well known CKW inequality. When a qubit pair is part of a four qubit pure state, it may be entangled to the rest of the system through two-way, three-way and four-way correlations. Monogamy equalities, satisfied by two-way, three-way and four-way non-local quantum correlatios are presented for states belonging to classes of four qubit pure states with distinct entanglement types. We gratefully acknowledge financial support from CNPq and Capes Brazil.

  2. A Common Force-Sharing Pattern in Joint Action That Consists of Four People.

    PubMed

    Masumoto, Junya; Inui, Nobuyuki

    2017-12-20

    The authors examined the force-sharing patterns in a joint action performed by a group of two, three, or four people compared with a solo action. In the joint actions, 28 participants produced periodic isometric forces such that the sum of forces they produced cycled between 5% and 10% maximum voluntary contraction with the right hand at 1 Hz. In both the three- and four-person tasks, the correlation between forces produced by two of the three or four participants was negative, and the remaining one or two participants produced intermediate forces. The errors of force and interval and force variabilities were smaller in four- and three-people groups than individuals. Four- and three-people groups thus performed better than individuals.

  3. On monogamy of four-qubit entanglement

    NASA Astrophysics Data System (ADS)

    Sharma, S. Shelly; Sharma, N. K.

    2018-07-01

    Our main result is a monogamy inequality satisfied by the entanglement of a focus qubit (one-tangle) in a four-qubit pure state and entanglement of subsystems. Analytical relations between three-tangles of three-qubit marginal states, two-tangles of two-qubit marginal states and unitary invariants of four-qubit pure state are used to obtain the inequality. The contribution of three-tangle to one-tangle is found to be half of that suggested by a simple extension of entanglement monogamy relation for three qubits. On the other hand, an additional contribution due to a two-qubit invariant which is a function of three-way correlations is found. We also show that four-qubit monogamy inequality conjecture of Regula et al. (Phys Rev Lett 113:110501, 2014), in which three-tangles are raised to the power 3/2, does not estimate the residual correlations, correctly, for certain subsets of four-qubit states. A lower bound on residual four-qubit correlations is obtained.

  4. The Differences among Three-, Four-, and Five-Option-Item Formats in the Context of a High-Stakes English-Language Listening Test

    ERIC Educational Resources Information Center

    Lee, HyeSun; Winke, Paula

    2013-01-01

    We adapted three practice College Scholastic Ability Tests (CSAT) of English listening, each with five-option items, to create four- and three-option versions by asking 73 Korean speakers or learners of English to eliminate the least plausible options in two rounds. Two hundred and sixty-four Korean high school English-language learners formed…

  5. Two-, Three-, and Four-Year Follow-Up on the Self-Regulatory Treatment of Chronic Headache.

    ERIC Educational Resources Information Center

    Blanchard, Edward B.; And Others

    1987-01-01

    Chronic tension and vascular headache patients, initially treated with relaxation and biofeedback, were followed-up on an annual basis at two-, three-, and four-years posttreatment. Tension headache patients generally showed good maintenance of initial headache reduction at Year Four. Vascular patients showed a nonsignificant trend for gradual…

  6. Wood Preference of Reticulitermes virginicus (Blattodea: Rhinotermitidae) Using No-, Two-, and Four-Choice Designs and Seven Different Measures of Wood Consumption.

    PubMed

    Lee, T-Y; Forschler, B T

    2016-04-01

    Three hundred Reticulitermes virginicus (Banks) workers were exposed to three 1-cm3 wood blocks of either Quercus sp. (Red Oak), Populus sp. (Poplar), Pinus sp. (Pine), or Sequoia sp. (Redwood) placed into one of the three bioassay designs (no-, two-, and four-choice) for 21 d. Termite wood consumption was measured by wood weight loss, resistance class, and visual rating. Wood consumption rates were determined using four formulas in addition to two standardized visual rating scales (American Society for Testing and Materials [ASTM] and American Wood Protection Association [AWPA]) and a preference ranking obtained for each measure. The wood consumption formula, rating scale, and preference rankings were compared by bioassay design. The overall preference ranking of the four wood types as determined by the combination of all three designs was—1) Pine, 2) Red Oak, 3) Redwood, and 4) Poplar. Results indicate that bioassay design influenced both wood consumption and preference rankings. A no-choice design can determine aversion; a four-choice design the most preferred wood; and a two-choice design can illuminate the fine details of comparative preference. The different formulas employed for calculation of consumption rate influenced preference ranking in the no- and four-choice designs but not the two-choice design.

  7. Trisections in Three and Four Dimensions

    NASA Astrophysics Data System (ADS)

    Koenig, Dale R.

    Every closed orientable three dimensional manifold has a Heegaard splitting, a decomposition into two handlebodies. Any two Heegaard splittings of the same manifold can be made isotopic after a finite number of stabilization operations. The notion of trisections, developed by Gay and Kirby, provided an analogue in four dimensions. They showed that any closed smooth orientable four dimensional manifold can be broken into three four dimensional handlebodies, with "niceness" conditions on their intersections, and showed that any two trisections are isotopic after stabilizations. In this thesis we investigate the notion of trisections in both three and four dimensions. In dimension three we define trisections of 3-manifolds and stabilization on these trisections. We use this to define the trisection genus of a 3-manifold. We then present several examples, showing among other things that the trisection genus is not additive under connect sum. We prove a stable equivalence theorem for trisections of 3-manifolds, showing that any two trisections of the same three-manifold can be made isotopic after stabilizations. We also show that trisections of S3 can be very complicated, so there is no analogue of Waldhausen's theorem for trisections of three manifolds. We then move on to trisections in four dimensions. We first show that if there exist four manifolds with unbalanced trisection genus lower than their balanced trisection genus, then trisection genus as defined by Gay and Kirby is not additive under connect sum. We produce several new classes of trisections, including several likely such examples. We include a class of examples that are provably minimal genus. We provide trisection diagrams for many of these trisections, and summarize some methods for quickly checking that these diagrams produce valid trisections.

  8. Effect of the number of blades and solidity on the performance of a vertical axis wind turbine

    NASA Astrophysics Data System (ADS)

    Delafin, PL; Nishino, T.; Wang, L.; Kolios, A.

    2016-09-01

    Two, three and four bladed ϕ-shape Vertical Axis Wind Turbines are simulated using a free-wake vortex model. Two versions of the three and four bladed turbines are considered, one having the same chord length as the two-bladed turbine and the other having the same solidity as the two-bladed turbine. Results of the two-bladed turbine are validated against published experimental data of power coefficient and instantaneous torque. The effect of solidity on the power coefficient is presented and the instantaneous torque, thrust and lateral force of the two-, three- and four-bladed turbines are compared for the same solidity. It is found that increasing the number of blades from two to three significantly reduces the torque, thrust and lateral force ripples. Adding a fourth blade further reduces the ripples except for the torque at low tip speed ratio. This work aims to help choosing the number of blades during the design phase of a vertical axis wind turbine.

  9. Four-body trajectory optimization

    NASA Technical Reports Server (NTRS)

    Pu, C. L.; Edelbaum, T. N.

    1973-01-01

    A collection of typical three-body trajectories from the L1 libration point on the sun-earth line to the earth is presented. These trajectories in the sun-earth system are grouped into four distinct families which differ in transfer time and delta V requirements. Curves showing the variations of delta V with respect to transfer time, and typical two and three-impulse primer vector histories, are included. The development of a four-body trajectory optimization program to compute fuel optimal trajectories between the earth and a point in the sun-earth-moon system are also discussed. Methods for generating fuel optimal two-impulse trajectories which originate at the earth or a point in space, and fuel optimal three-impulse trajectories between two points in space, are presented. A brief qualitative comparison of these methods is given. An example of a four-body two-impulse transfer from the Li libration point to the earth is included.

  10. Mapping the four-horned locus and testing the polled locus in three Chinese sheep breeds.

    PubMed

    He, Xiaohong; Zhou, Zhengkui; Pu, Yabin; Chen, Xiaofei; Ma, Yuehui; Jiang, Lin

    2016-10-01

    Four-horned sheep are an ideal animal model for illuminating the genetic basis of horn development. The objective of this study was to locate the genetic region responsible for the four-horned phenotype and to verify a previously reported polled locus in three Chinese breeds. A genome-wide association study (GWAS) was performed using 34 two-horned and 32 four-horned sheep from three Chinese indigenous breeds: Altay, Mongolian and Sishui Fur sheep. The top two significant single nucleotide polymorphisms (SNPs) associated with the four-horned phenotype were both located in a region spanning positions 132.6 to 132.7 Mb on sheep chromosome 2. Similar locations for the four-horned trait were previously identified in Jacob, Navajo-Churro, Damara and Sishui Fur sheep, suggesting a common genetic component underlying the four-horned phenotype. The two identified SNPs were both downstream of the metaxin 2 (MTX2) gene and the HOXD gene cluster. For the top SNP-OAR2:g.132619300G>A-the strong associations of the AA and AG genotypes with the four-horned phenotype and the GG genotype with the two-horned phenotype indicated the dominant inheritance of the four-horned trait. No significant SNPs for the polled phenotype were identified in the GWAS analysis, and a PCR analysis for the detection of the 1.8-kb insertion associated with polled sheep in other breeds failed to verify the association with polledness in the three Chinese breeds. This study supports the hypothesis that two different loci are responsible for horn existence and number. This study contributes to the understanding of the molecular regulation of horn development and enriches the knowledge of qualitative traits in domestic animals. © 2016 Stichting International Foundation for Animal Genetics.

  11. 76 FR 57728 - Texas Eastern Transmission, LP, Algonquin Gas Transmission, LLC; Notice of Availability of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-16

    ... protection regulation at two existing M&R stations; Installation of three pig launchers and two pig receivers, relocation of four pig receivers, and removal of two pig launchers; Installation of four mainline and three... to accommodate a temporary pig receiver. The draft EIS has been placed in the public files of the...

  12. Maxwell's conjecture on three point charges with equal magnitudes

    NASA Astrophysics Data System (ADS)

    Tsai, Ya-Lun

    2015-08-01

    Maxwell's conjecture on three point charges states that the number of non-degenerate equilibrium points of the electrostatic field generated by them in R3 is at most four. We prove the conjecture in the cases when three point charges have equal magnitudes and show the number of isolated equilibrium points can only be zero, two, three, or four. Specifically, fixing positions of two positive charges in R3, we know exactly where to place the third positive charge to have two, three, or four equilibrium points. All equilibrium points are isolated and there are no other possibilities for the number of isolated equilibrium points. On the other hand, if both two of the fixed charges have negative charge values, there are always two equilibrium points except when the third positive charge lies in the line segment connecting the two negative charges. The exception cases are when the field contains only a curve of equilibrium points. In this paper, computations assisted by computer involve symbolic and exact integer computations. Therefore, all the results are proved rigorously.

  13. Critical anisotropies of a geometrically frustrated triangular-lattice antiferromagnet

    NASA Astrophysics Data System (ADS)

    Swanson, M.; Haraldsen, J. T.; Fishman, R. S.

    2009-05-01

    This work examines the critical anisotropy required for the local stability of the collinear ground states of a geometrically frustrated triangular-lattice antiferromagnet (TLA). Using a Holstein-Primakoff expansion, we calculate the spin-wave frequencies for the one-, two-, three-, four-, and eight-sublattice (SL) ground states of a TLA with up to third neighbor interactions. Local stability requires that all spin-wave frequencies are real and positive. The two-, four-, and eight-SL phases break up into several regions where the critical anisotropy is a different function of the exchange parameters. We find that the critical anisotropy is a continuous function everywhere except across the two-SL/three-SL and three-SL/four-SL phase boundaries, where the three-SL phase has the higher critical anisotropy.

  14. Mach number scaling of helicopter rotor blade/vortex interaction noise

    NASA Technical Reports Server (NTRS)

    Leighton, Kenneth P.; Harris, Wesley L.

    1985-01-01

    A parametric study of model helicopter rotor blade slap due to blade vortex interaction (BVI) was conducted in a 5 by 7.5-foot anechoic wind tunnel using model helicopter rotors with two, three, and four blades. The results were compared with a previously developed Mach number scaling theory. Three- and four-bladed rotor configurations were found to show very good agreement with the Mach number to the sixth power law for all conditions tested. A reduction of conditions for which BVI blade slap is detected was observed for three-bladed rotors when compared to the two-bladed baseline. The advance ratio boundaries of the four-bladed rotor exhibited an angular dependence not present for the two-bladed configuration. The upper limits for the advance ratio boundaries of the four-bladed rotors increased with increasing rotational speed.

  15. Local Gram-Schmidt and covariant Lyapunov vectors and exponents for three harmonic oscillator problems

    NASA Astrophysics Data System (ADS)

    Hoover, Wm. G.; Hoover, Carol G.

    2012-02-01

    We compare the Gram-Schmidt and covariant phase-space-basis-vector descriptions for three time-reversible harmonic oscillator problems, in two, three, and four phase-space dimensions respectively. The two-dimensional problem can be solved analytically. The three-dimensional and four-dimensional problems studied here are simultaneously chaotic, time-reversible, and dissipative. Our treatment is intended to be pedagogical, for use in an updated version of our book on Time Reversibility, Computer Simulation, and Chaos. Comments are very welcome.

  16. Speech-Action Coordination in Young Children.

    ERIC Educational Resources Information Center

    Balamore, Usha; Wozniak, Robert H.

    1984-01-01

    Speech-action coordination in 100 three and four year olds was measured according to a modified version of Wozniak's hammering-board task. Four instructional conditions (instructional, demonstration, vocalization, no vocalization) were presented in a numerical task ("Hit four times") and in two spatial tasks: three-color ("Hit red,…

  17. Effect of restricted motion in high temperature on enzymatic activity of the pancreas

    NASA Technical Reports Server (NTRS)

    Abdusattarov, A.; Smirnova, G. I.

    1980-01-01

    Effects of 30 day hypodynamia coupled with high temperature (35-36 C) on enzymatic activity of the pancreas of male adult rats were studied. The test animals were divided into four groups. Group one served as controls (freedom of movement and a temperature of 25-26 C, considered optimal). The remaining animals were divided into three additional groups: Group two freedom of movement but high temperature (35-36 C); group three hypodynamia but an optimal temperature; group four hypodynamia and 35-36 C. Considerable change in the enzymatic activity in the pancreas of the four groups is observed in three experimental groups (two, three, and four) as compared to the control (group one). The results indicate that adaption of the organism to the thermal factor and restricted movement is accompanied by a change in the enzymatic spectrum of the pancreas. With the combined effect of these two stresses under conditions of the adaption of the organism especially sharp shifts occur in the enzymatic activity.

  18. Chemistry of Living Matter, Energy Capture & Growth, Parts Three & Four of an Integrated Science Sequence, Teacher's Guide, 1973 Edition.

    ERIC Educational Resources Information Center

    Portland Project Committee, OR.

    This teacher's guide includes parts three and four of the four-part third year Portland Project, a three-year integrated secondary science curriculum sequence. The underlying intention of the third year is to study energy and its importance to life. Energy-related concepts considered in year one and two, and the concepts related to atomic…

  19. 21 CFR 150.160 - Fruit preserves and jams.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... jams. (a) The preserves or jams for which definitions and standards of identity are prescribed by this... combination of two, three, four, or five of such fruits in which the weight of each is not less than one-fifth... of the weight of the combination. (ii) Any combination of apple and one, two, three, or four of such...

  20. SU-E-T-340: Use of Intensity Modulated Proton Therapy (IMPT) for Reducing the Dose to Cochlea in Craniospinal Irradiation (CSI) of Pediatric Patients

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dormer, J; Kassaee, A; Lin, H

    2014-06-01

    Purpose: To evaluate use of intensity modulated proton therapy (IMPT) and number of beams for sparing cochlea in treatment of whole brain for pediatric medulloblastoma patients. Methods: In our institution, craniospinal irradiation patients are treated in supine position on our proton gantries using pencil beam scanning with each beam uniformly covering the target volume (SFUD). Each treatment plan consists of two opposed lateral whole brain fields and one or two spinal fields. For sparing the cochlea for the whole brain treatment, we created three different plans using IMPT for five pediatric patients. The first plan consisted of two lateral fields,more » the second two lateral fields and a superior-inferior field, and the third two lateral fields and two superior oblique fields. Optimization was performed with heavy weights applied to the eye, lens and cochlea while maintaining a dose prescription of 36 Gy to the whole brain. Results: IMPT plans reduce the dose to the cochlea. Increasing the number of treatment fields was found to lower the average dose to the cochlea: 15.0, 14.5 and 12.5 Gy for the two-field, three-field, and four-field plans respectively. The D95 for the two-field plan was 98.2%, compared to 100.0% for both the three-field and four-field plan. Coverage in the mid-brain was noticeably better in the three- and four-field plans, with more dose conformality surrounding the cochlea. Conclusion: IMPT plans for CSI and the whole brain irradiations are capable of sparing cochlea and reduce the dose considerably without compromising treating brain tissues. The reduction in average dose increases with three and four field plans as compared to traditional two lateral beam plans.« less

  1. Dental Assisting Education in California.

    ERIC Educational Resources Information Center

    California State Dept. of Education, Sacramento. Bureau of Industrial Education.

    A survey of 22 dental assisting programs showed an average of 1,124 hours of instruction in dental assisting for 15 four-semester, 955 for three three-semester, and 1,042 for four two-semester programs. The average instructional hours for the four-semester programs were 48 in introduction to dental assisting, 179 in the life sciences, 221 in the…

  2. Paintability of four woods in Hawaii

    Treesearch

    Roger G. Skolmen

    1972-01-01

    Four paint combinations applied to simulated vertical siding of four wood species have been exposed outdoors in Hawaii since 1964. A three-coat, self-primed latex application is holding up best, with oil base primed latex, three-coat oil base, and two-coat oil base combinations next best in that order. Australian toon is holding paint best, followed by redwood, robusta...

  3. Effects of Amphetamine-CNS Depressant Combinations and of Other CNS Stimulants in Four-Choice Drug Discriminations

    ERIC Educational Resources Information Center

    Li, Mi; Wessinger, William D.; McMillan, D. E.

    2005-01-01

    Three pigeons were trained to discriminate among 5 mg/kg pentobarbital, 2 mg/kg amphetamine, a combination of these two drugs at these doses, and saline using a four-choice procedure (amphetamine--pentobarbital group). Three other pigeons were trained to discriminate among 5 mg/kg morphine, 2 mg/kg methamphetamine, a combination of these two drugs…

  4. Two-, three-, and four-poster jets in cross flow

    NASA Technical Reports Server (NTRS)

    Vukits, Thomas J.; Sullivan, John P.; Murthy, S. N. B.

    1993-01-01

    In connection with the problems of the ingestion of hot exhaust gases in engines of V/STOL and STOVL aircraft in ground effect, a series of studies have been undertaken. Ground impinging, two- and three-poster jets operating in the presence of cross flow were studied. The current paper is divided into two parts. The first part is a comparison of the low speed, two-, three-, and four-poster jet cases, with respect to the flowfield in the region of interaction between the forward and the jet flows. These include cases with mass balanced inlet suction. An analysis of the inlet entry plane of the low speed two- and three-poster jet cases is also given. In the second part, high speed results for a two jet configuration without inlet suction are given. The results are based on quantitative, marker concentration distributions obtained by digitizing video images.

  5. Periodic orbits in the restricted four-body problem with two equal masses

    NASA Astrophysics Data System (ADS)

    Burgos-García, Jaime; Delgado, Joaquín

    2013-06-01

    The restricted (equilateral) four-body problem consists of three bodies of masses m 1, m 2 and m 3 (called primaries) lying in a Lagrangian configuration of the three-body problem i.e., they remain fixed at the apices of an equilateral triangle in a rotating coordinate system. A massless fourth body moves under the Newtonian gravitation law due to the three primaries; as in the restricted three-body problem (R3BP), the fourth mass does not affect the motion of the three primaries. In this paper we explore symmetric periodic orbits of the restricted four-body problem (R4BP) for the case of two equal masses where they satisfy approximately the Routh's critical value. We will classify them in nine families of periodic orbits. We offer an exhaustive study of each family and the stability of each of them.

  6. Oak Regeneration: Four Years After Three Harvesting Treatments in a North Alabama Upland Hardwood Stand

    Treesearch

    David Shostak; Michael S. Golden; Mark R. Dubois

    2002-01-01

    Fourth year regeneration of upland oaks (Quercus spp.) was compared within three harvesting treatments in the mountains of northern Alabama. Six four-acre experimental blocks were established on north facing slopes. Each of the three harvesting treatments (deferment cutting, strip clearcutting, and block clearcutting) was randomly assigned to two...

  7. AIDS therapy with two, three or four agent combinations, applied in short sequences, differing from each other by drug rotation. I. First of two parts: a phase I trial equivalent, concerning five virostatics: AZT, ddI, ddC, acriflavine and an ellipticine analogue.

    PubMed

    Mathé, G; Pontiggia, P; Orbach-Arbouys, S; Triana, K; Ambetima, N; Morette, C; Hallard, M; Blanquet, D

    1996-01-01

    We have individually treated ten AIDS patients whose CD4 numbers were inferior to 200/mm3, with the five following HIV1 virostatics: a) azido-deoxythymidine (AZT), dideoxyinosine (ddI) and dideoxycytidine (ddC), which affect the same viral target, retrotranscriptase, b) acriflavine (ACF) and methyl-hydroxy-ellipticine (MHE) which we have discovered to be strong virostatics in vivo, in mice, against Friend's virus, and in man, against AZT resistant HIV1. We have shown that their combinations with AZT, hitting three viral targets, reduces in mice, the blood Friend's virus load below detectable level. Due to the short doubling time of HIV1, AIDS therapy must be continuous, and to allow the best tolerance, the five virostatic combinations were applied in short, three-week sequences, each differing as much as possible from the former and from the following one, due to drug rotation [1]. Among the ten patients, a) three received the two-drug combinations for 15 to 30 months, followed by the three-drug combinations, b) three received the three-drug combinations from the beginning, c) four received the four-drug combinations also from the beginning, two having less than 10 CD4/mm3 at initiation of treatment, and two having more than 100. The tolerance was remarkable: the only side-effect being macrocytosis. The application of the two-drug combination sequences maintained stable CD4 levels in two subjects whose viral load (the evaluation of which had became available) was, at the end of this period, of 4,486 and 39,238 RNA copies. The third subject who had received, an intensive UV irradiation for a psoriasis, presented an irreversible decrease in his CD4 count and a high viral load (1,352,495 RNA copies/mL) at the end of the two-drug period. Fifteen to 25 months after the shift to the three-drug combinations, the viral load decreased, from 39,328 to 13,291 in one of the non-UV irradiated subjects, and from 1,352,495 to 314,387 in the irradiated one. No subject had an increase in CD4 number. In the three patients having initially received the three-drug combinations, a very strong decrease of viral load was registered after periods of observation varying from 77 to 40 months, while the CD4 counts increased moderately in two subjects, and noticeably in the third (from 126 to 266). Out of the four subjects initially treated with four-drug combinations, the two with less than 10 CD4/mm3 had a moderate decrease in viral load in about three months, and the CD4 increased from 9 to 34/mm3 in one. But the two subjects, because of opportunistic infections and psychological reasons, abandoned their treatments. In the two subjects who had more than 100 CD4/mm2 at initiation of the four-drug combination treatment, the viral load decreased to undetectable levels after four months: but their CD4 counts, after some oscillations, had very moderately increased at the end of the observation period (respectively, from 200 to 222, and from 129 to 134). In practice, these results suggest the interest of conducting phase II or III studies of AIDS treatment protocols, starting with the four-drug combination model, and attempting to maintain the effect with the three-drug combination one. As for theoretical considerations, one must underline the contrast between the remarkable reduction of the viral load and the usually moderate increase of the CD4 counts. The study but not the trial has been interrupted, due to the unavailability of three antiproteases, saquinavir, ritonavir and indinavir, which are now introduced in the same type of combinations, one by one, in replacement of one of the studied agents as shown in figure 1. The effect of increasing the total number of virostatics from five to eight will be published in the second part of this article series.

  8. Numerical calculation of phase-matching properties in photonic crystal fibers with three and four zero-dispersion wavelengths.

    PubMed

    Zhao, Xingtao; Liu, Xiaoxu; Wang, Shutao; Wang, Wei; Han, Ying; Liu, Zhaolun; Li, Shuguang; Hou, Lantian

    2015-10-19

    Photonic crystal fibers with three and four zero-dispersion wavelengths are presented through special design of the structural parameters, in which the closing to zero and ultra-flattened dispersion can be obtained. The unique phase-matching properties of the fibers with three and four zero-dispersion wavelengths are analyzed. Variation of the phase-matching wavelengths with the pump wavelengths, pump powers, dispersion properties, and fiber structural parameters is analyzed. The presence of three and four zero-dispersion wavelengths can realize wavelength conversion of optical soliton between two anomalous dispersion regions, generate six phase-matching sidebands through four-wave mixing and create more new photon pairs, which can be used for the study of supercontinuum generation, optical switches and quantum optics.

  9. Mice and Men Environmental Balance, Parts Three and Four of an Integrated Science Sequence, Student Guide, 1970 Edition.

    ERIC Educational Resources Information Center

    Portland Project Committee, OR.

    This student guide is divided into two sections: "Mice and Men" and "Environmental Balance," and constitutes parts three and four of the first year of the Portland Project, a three-year, integrated high school science curriculum. Part One of the guide deals with topics such as cell, reproduction, embryology, genetics, genetic…

  10. Four Professors, Three Universities, Two Modes of Technology, and One Eighth Grade Classroom: Collaboration in Middle Level Teacher Education

    ERIC Educational Resources Information Center

    Howell, Penny B.; Rintamaa, Margaret; Faulkner, Shawn; DiCicco, Mike

    2017-01-01

    This article focuses on four university teacher educators across three mid-western institutions working together to collaborate and develop a shared understanding of practice in middle level teacher education while modeling a team approach to teaching and learning. Three institutions, University of Louisville (UL), University of Kentucky (UK), and…

  11. Equivalent D = 3 supergravity amplitudes from double copies of three-algebra and two-algebra gauge theories.

    PubMed

    Huang, Yu-tin; Johansson, Henrik

    2013-04-26

    We show that three-dimensional supergravity amplitudes can be obtained as double copies of either three-algebra super-Chern-Simons matter theory or two-algebra super-Yang-Mills theory when either theory is organized to display the color-kinematics duality. We prove that only helicity-conserving four-dimensional gravity amplitudes have nonvanishing descendants when reduced to three dimensions, implying the vanishing of odd-multiplicity S-matrix elements, in agreement with Chern-Simons matter theory. We explicitly verify the double-copy correspondence at four and six points for N = 12,10,8 supergravity theories and discuss its validity for all multiplicity.

  12. Lax representations for matrix short pulse equations

    NASA Astrophysics Data System (ADS)

    Popowicz, Z.

    2017-10-01

    The Lax representation for different matrix generalizations of Short Pulse Equations (SPEs) is considered. The four-dimensional Lax representations of four-component Matsuno, Feng, and Dimakis-Müller-Hoissen-Matsuno equations are obtained. The four-component Feng system is defined by generalization of the two-dimensional Lax representation to the four-component case. This system reduces to the original Feng equation, to the two-component Matsuno equation, or to the Yao-Zang equation. The three-component version of the Feng equation is presented. The four-component version of the Matsuno equation with its Lax representation is given. This equation reduces the new two-component Feng system. The two-component Dimakis-Müller-Hoissen-Matsuno equations are generalized to the four-parameter family of the four-component SPE. The bi-Hamiltonian structure of this generalization, for special values of parameters, is defined. This four-component SPE in special cases reduces to the new two-component SPE.

  13. Guidelines for the conversion of urban four-lane undivided roadways to three-lane two-way left-turn lane facilities

    DOT National Transportation Integrated Search

    2001-04-01

    The primary objective of this research project was to develop a set of guidelines to assist in the selection of candidate roadways for urban four-lane undivided to three-lane cross section conversions. The authors evaluated and assessed the physical,...

  14. 7 CFR 1212.41 - Term of office.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... members shall be staggered for two-, three-, and four-year terms. For the initial Board, one producer, one... serve a three-year term of office. One producer, one first handler, and one importer will serve a four...

  15. Assessing the acquisition and generalization of two mand forms with adults with severe developmental disabilities.

    PubMed

    Chambers, Mark; Rehfeldt, Ruth Anne

    2003-01-01

    The purpose of this study was to determine whether manual sign or the Picture Exchange Communication System (P.E.C.S.) (Frost and Bondy, 1994) would be more effective in teaching mand skills to adults with mental retardation in the severe and profound range. Four participants were taught to mand for four reinforcing items using both communication modalities, in an alternating treatments design. Three of four participants demonstrated criterion performance across all four mands using P.E.C.S. first. Two of those three participants later demonstrated criterion performance for the mands using manual sign. The fourth participant was removed from the study during training due to illness, but her progress indicated greater acquisition with P.E.C.S. Generalization probes conducted at participants' respective residences showed that three participants demonstrated generalization across settings using P.E.C.S., and two participants demonstrated generalization across settings using manual sign. Participants were also more likely to mand for reinforcing items not present using P.E.C.S. than using manual sign.

  16. Chemistry of Living Matter, Energy Capture & Growth, Parts Three & Four of an Integrated Science Sequence, Student Guide, 1971 Edition.

    ERIC Educational Resources Information Center

    Portland Project Committee, OR.

    This student guide is divided into two sections, "Chemistry of Living Matter" and "Energy Capture and Growth," constituting parts three and four of the third year of the Portland Project, a three-year high school integrated science curriculum. The underlying intention of the third year is to study energy and its importance to…

  17. In vitro evaluation of the flexural properties of All-on-Four provisional fixed denture base resin partially reinforced with fibers.

    PubMed

    Li, Bei Bei; Xu, Jia Bin; Cui, Hong Yan; Lin, Ye; Di, Ping

    2016-01-01

    The aim of this study was to assess the effects of partial carbon or glass fiber reinforcement on the flexural properties of All-on-Four provisional fixed denture base resin. The carbon or glass fibers were woven (3% by weight) together in three strands and twisted and tightened between the two abutments in a figure-of-"8" pattern. Four types of specimens were fabricated for the three-point loading test. The interface between the denture base resin and fibers was examined using scanning electron microscopy (SEM). Reinforcement with carbon or glass fibers between two abutments significantly increased the flexural strength and flexural modulus. SEM revealed relatively continuous contact between the fibers and acrylic resin. The addition of carbon or glass fibers between two abutments placed on All-on-Four provisional fixed denture base resin may be clinically effective in preventing All-on-Four denture fracture and can provide several advantages for clinical use.

  18. 7 CFR 1219.35 - Term of office.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... years, except the members of the initial Board shall serve terms as follows: Four members and four alternates shall serve for two-year terms; four members and four alternates shall serve for three-year terms...

  19. Health sciences library building projects, 1996-1997 survey.

    PubMed Central

    Bowden, V M

    1998-01-01

    Nine building projects are briefly described, including four new libraries, two renovations, and three combined renovations and additions. The libraries range in size from 657 square feet to 136,832 square feet, with seating varying from 14 to 635. Three hospital libraries and four academic health sciences libraries are described in more detail. In each case an important consideration was the provision for computer access. Two of the libraries expanded their space for historical collections. Three of the libraries added mobile shelving as a way of storing print materials while providing space for other activities. Images PMID:9549012

  20. Healing of osteotomy sites applying either piezosurgery or two conventional saw blades: a pilot study in rabbits.

    PubMed

    Ma, Li; Stübinger, Stefan; Liu, Xi Ling; Schneider, Urs A; Lang, Niklaus P

    2013-08-01

    The purpose of this study was to compare bone healing of experimental osteotomies applying either piezosurgery or two different oscillating saw blades in a rabbit model. The 16 rabbits were randomly assigned into four groups to comply with observation periods of one, two, three and five weeks. In all animals, four osteotomy lines were performed on the left and right nasal bone using a conventional saw blade, a novel saw blade and piezosurgery. All three osteotomy techniques revealed an advanced gap healing starting after one week. The most pronounced new bone formation took place between two and three weeks, whereby piezoelectric surgery revealed a tendency to faster bone formation and remodelling. Yet, there were no significant differences between the three modalities. The use of a novel as well as the piezoelectric bone-cutting instrument revealed advanced bone healing with a favourable surgical performance compared to a traditional saw.

  1. Three axis velocity probe system

    DOEpatents

    Fasching, George E.; Smith, Jr., Nelson S.; Utt, Carroll E.

    1992-01-01

    A three-axis velocity probe system for determining three-axis positional velocities of small particles in fluidized bed systems and similar applications. This system has a sensor head containing four closely-spaced sensing electrodes of small wires that have flat ends to establish a two axis plane, e.g. a X-Y plane. Two of the sensing electrodes are positioned along one of the axes and the other two are along the second axis. These four sensing electrodes are surrounded by a guard electrode, and the outer surface is a ground electrode and support member for the sensing head. The electrodes are excited by, for example, sinusoidal voltage having a peak-to-peak voltage of up to 500 volts at a frequency of 2 MHz. Capacitive currents flowing between the four sensing electrodes and the ground electrode are influenced by the presence and position of a particle passing the sensing head. Any changes in these currents due to the particle are amplified and synchronously detected to produce positional signal values that are converted to digital form. Using these digital forms and two values of time permit generation of values of the three components of the particle vector and thus the total velocity vector.

  2. Evaluation of chlorophyll-a retrieval algorithms based on MERIS bands for optically varying eutrophic inland lakes.

    PubMed

    Lyu, Heng; Li, Xiaojun; Wang, Yannan; Jin, Qi; Cao, Kai; Wang, Qiao; Li, Yunmei

    2015-10-15

    Fourteen field campaigns were conducted in five inland lakes during different seasons between 2006 and 2013, and a total of 398 water samples with varying optical characteristics were collected. The characteristics were analyzed based on remote sensing reflectance, and an automatic cluster two-step method was applied for water classification. The inland waters could be clustered into three types, which we labeled water types I, II and III. From water types I to III, the effect of the phytoplankton on the optical characteristics gradually decreased. Four chlorophyll-a retrieval algorithms for Case II water, a two-band, three-band, four-band and SCI (Synthetic Chlorophyll Index) algorithm were evaluated for three water types based on the MERIS bands. Different MERIS bands were used for the three water types in each of the four algorithms. The four algorithms had different levels of retrieval accuracy for each water type, and no single algorithm could be successfully applied to all water types. For water types I and III, the three-band algorithm performed the best, while the four-band algorithm had the highest retrieval accuracy for water type II. However, the three-band algorithm is preferable to the two-band algorithm for turbid eutrophic inland waters. The SCI algorithm is recommended for highly turbid water with a higher concentration of total suspended solids. Our research indicates that the chlorophyll-a concentration retrieval by remote sensing for optically contrasted inland water requires a specific algorithm that is based on the optical characteristics of inland water bodies to obtain higher estimation accuracy. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. The Development of Comprehensive Search Skills.

    ERIC Educational Resources Information Center

    Wellman, Henry M.; And Others

    1984-01-01

    One experiment examined two and one-half, three and one-half and four and one-half year olds' ability to conduct nonredundant comprehensive searches of small lidded trash cans. A second experiment examined three , four, and five year olds' ability to find Easter eggs hidden on a large playground. Results were discussed in relation to developmental…

  4. Activities of the National Institute of Radiological Sciences

    NASA Astrophysics Data System (ADS)

    1994-01-01

    This annual report presents activities at the National Institute of Radiological Sciences (NIRS) in Japan during the period April 1992-March 1993. The activities are divided into research, technical aids, training, medical services, management, library or editing, and international cooperation. Research activities are arranged with twelve sections. The first section on special researches deals with continuing research projects entitled: (1) 'Biological Risk Evaluation in Public Exposure'; (2) 'Exposure Assessment in the Environment and the Public Through Food Chain'; (3) 'Medical Use of Accelerated Heavy Ions'; and (4) 'Preliminary Study for the Demonstration of Dose-Response Relationships in Low-Dose Range'. All projects except for project (4) will be finished up to March 1993. The section of assigned researches covers four titles. The section of ordinary researches covers physics (four titles), pharmacochemistry (four), biology (three), genetics (four), physiopathology (four), cytological radiation injuries (three), internal exposure (four), environmental science (four), clinical research (four), clinical research for radiation injuries (three), medical use of heavy particles (three), environmental radiation ecology (three), and aquatic radiation ecology (two). The section on technical aids gives an overview of technical services, radiation safety, animal and plant management, and cyclotron management. Appendices give the information on personnel in NIRS.

  5. Multipion Bose-Einstein correlations in p p ,p -Pb, and Pb-Pb collisions at energies available at the CERN Large Hadron Collider

    NASA Astrophysics Data System (ADS)

    Adam, J.; Adamová, D.; Aggarwal, M. M.; Aglieri Rinella, G.; Agnello, M.; Agrawal, N.; Ahammed, Z.; Ahmad, S.; Ahn, S. U.; Aiola, S.; Akindinov, A.; Alam, S. N.; Aleksandrov, D.; Alessandro, B.; Alexandre, D.; Alfaro Molina, R.; Alici, A.; Alkin, A.; Almaraz, J. R. M.; Alme, J.; Alt, T.; Altinpinar, S.; Altsybeev, I.; Alves Garcia Prado, C.; Andrei, C.; Andronic, A.; Anguelov, V.; Antičić, T.; Antinori, F.; Antonioli, P.; Aphecetche, L.; Appelshäuser, H.; Arcelli, S.; Arnaldi, R.; Arnold, O. W.; Arsene, I. C.; Arslandok, M.; Audurier, B.; Augustinus, A.; Averbeck, R.; Azmi, M. D.; Badalà, A.; Baek, Y. W.; Bagnasco, S.; Bailhache, R.; Bala, R.; Balasubramanian, S.; Baldisseri, A.; Baral, R. C.; Barbano, A. M.; Barbera, R.; Barile, F.; Barnaföldi, G. G.; Barnby, L. S.; Barret, V.; Bartalini, P.; Barth, K.; Bartke, J.; Bartsch, E.; Basile, M.; Bastid, N.; Basu, S.; Bathen, B.; Batigne, G.; Batista Camejo, A.; Batyunya, B.; Batzing, P. C.; Bearden, I. G.; Beck, H.; Bedda, C.; Behera, N. K.; Belikov, I.; Bellini, F.; Bello Martinez, H.; Bellwied, R.; Belmont, R.; Belmont-Moreno, E.; Belyaev, V.; Benacek, P.; Bencedi, G.; Beole, S.; Berceanu, I.; Bercuci, A.; Berdnikov, Y.; Berenyi, D.; Bertens, R. A.; Berzano, D.; Betev, L.; Bhasin, A.; Bhat, I. R.; Bhati, A. K.; Bhattacharjee, B.; Bhom, J.; Bianchi, L.; Bianchi, N.; Bianchin, C.; Bielčík, J.; Bielčíková, J.; Bilandzic, A.; Biro, G.; Biswas, R.; Biswas, S.; Bjelogrlic, S.; Blair, J. T.; Blau, D.; Blume, C.; Bock, F.; Bogdanov, A.; Bøggild, H.; Boldizsár, L.; Bombara, M.; Book, J.; Borel, H.; Borissov, A.; Borri, M.; Bossú, F.; Botta, E.; Bourjau, C.; Braun-Munzinger, P.; Bregant, M.; Breitner, T.; Broker, T. A.; Browning, T. A.; Broz, M.; Brucken, E. J.; Bruna, E.; Bruno, G. E.; Budnikov, D.; Buesching, H.; Bufalino, S.; Buncic, P.; Busch, O.; Buthelezi, Z.; Butt, J. B.; Buxton, J. T.; Caffarri, D.; Cai, X.; Caines, H.; Calero Diaz, L.; Caliva, A.; Calvo Villar, E.; Camerini, P.; Carena, F.; Carena, W.; Carnesecchi, F.; Castillo Castellanos, J.; Castro, A. J.; Casula, E. A. R.; Ceballos Sanchez, C.; Cerello, P.; Cerkala, J.; Chang, B.; Chapeland, S.; Chartier, M.; Charvet, J. L.; Chattopadhyay, S.; Chattopadhyay, S.; Chauvin, A.; Chelnokov, V.; Cherney, M.; Cheshkov, C.; Cheynis, B.; Chibante Barroso, V.; Chinellato, D. D.; Cho, S.; Chochula, P.; Choi, K.; Chojnacki, M.; Choudhury, S.; Christakoglou, P.; Christensen, C. H.; Christiansen, P.; Chujo, T.; Chung, S. U.; Cicalo, C.; Cifarelli, L.; Cindolo, F.; Cleymans, J.; Colamaria, F.; Colella, D.; Collu, A.; Colocci, M.; Conesa Balbastre, G.; Conesa Del Valle, Z.; Connors, M. E.; Contreras, J. G.; Cormier, T. M.; Corrales Morales, Y.; Cortés Maldonado, I.; Cortese, P.; Cosentino, M. R.; Costa, F.; Crochet, P.; Cruz Albino, R.; Cuautle, E.; Cunqueiro, L.; Dahms, T.; Dainese, A.; Danisch, M. C.; Danu, A.; Das, D.; Das, I.; Das, S.; Dash, A.; Dash, S.; de, S.; de Caro, A.; de Cataldo, G.; de Conti, C.; de Cuveland, J.; de Falco, A.; de Gruttola, D.; De Marco, N.; de Pasquale, S.; Deisting, A.; Deloff, A.; Dénes, E.; Deplano, C.; Dhankher, P.; di Bari, D.; di Mauro, A.; di Nezza, P.; Diaz Corchero, M. A.; Dietel, T.; Dillenseger, P.; Divià, R.; Djuvsland, Ø.; Dobrin, A.; Domenicis Gimenez, D.; Dönigus, B.; Dordic, O.; Drozhzhova, T.; Dubey, A. K.; Dubla, A.; Ducroux, L.; Dupieux, P.; Ehlers, R. J.; Elia, D.; Endress, E.; Engel, H.; Epple, E.; Erazmus, B.; Erdemir, I.; Erhardt, F.; Espagnon, B.; Estienne, M.; Esumi, S.; Eum, J.; Evans, D.; Evdokimov, S.; Eyyubova, G.; Fabbietti, L.; Fabris, D.; Faivre, J.; Fantoni, A.; Fasel, M.; Feldkamp, L.; Feliciello, A.; Feofilov, G.; Ferencei, J.; Fernández Téllez, A.; Ferreiro, E. G.; Ferretti, A.; Festanti, A.; Feuillard, V. J. G.; Figiel, J.; Figueredo, M. A. S.; Filchagin, S.; Finogeev, D.; Fionda, F. M.; Fiore, E. M.; Fleck, M. G.; Floris, M.; Foertsch, S.; Foka, P.; Fokin, S.; Fragiacomo, E.; Francescon, A.; Frankenfeld, U.; Fronze, G. G.; Fuchs, U.; Furget, C.; Furs, A.; Fusco Girard, M.; Gaardhøje, J. J.; Gagliardi, M.; Gago, A. M.; Gallio, M.; Gangadharan, D. R.; Ganoti, P.; Gao, C.; Garabatos, C.; Garcia-Solis, E.; Gargiulo, C.; Gasik, P.; Gauger, E. F.; Germain, M.; Gheata, A.; Gheata, M.; Ghosh, P.; Ghosh, S. K.; Gianotti, P.; Giubellino, P.; Giubilato, P.; Gladysz-Dziadus, E.; Glässel, P.; Goméz Coral, D. M.; Gomez Ramirez, A.; Gonzalez, V.; González-Zamora, P.; Gorbunov, S.; Görlich, L.; Gotovac, S.; Grabski, V.; Grachov, O. A.; Graczykowski, L. K.; Graham, K. L.; Grelli, A.; Grigoras, A.; Grigoras, C.; Grigoriev, V.; Grigoryan, A.; Grigoryan, S.; Grinyov, B.; Grion, N.; Gronefeld, J. M.; Grosse-Oetringhaus, J. F.; Grossiord, J.-Y.; Grosso, R.; Guber, F.; Guernane, R.; Guerzoni, B.; Gulbrandsen, K.; Gunji, T.; Gupta, A.; Gupta, R.; Haake, R.; Haaland, Ø.; Hadjidakis, C.; Haiduc, M.; Hamagaki, H.; Hamar, G.; Hamon, J. C.; Harris, J. W.; Harton, A.; Hatzifotiadou, D.; Hayashi, S.; Heckel, S. T.; Helstrup, H.; Herghelegiu, A.; Herrera Corral, G.; Hess, B. A.; Hetland, K. F.; Hillemanns, H.; Hippolyte, B.; Horak, D.; Hosokawa, R.; Hristov, P.; Huang, M.; Humanic, T. J.; Hussain, N.; Hussain, T.; Hutter, D.; Hwang, D. S.; Ilkaev, R.; Inaba, M.; Incani, E.; Ippolitov, M.; Irfan, M.; Ivanov, M.; Ivanov, V.; Izucheev, V.; Jacazio, N.; Jacobs, P. M.; Jadhav, M. B.; Jadlovska, S.; Jadlovsky, J.; Jahnke, C.; Jakubowska, M. J.; Jang, H. J.; Janik, M. A.; Jayarathna, P. H. S. Y.; Jena, C.; Jena, S.; Jimenez Bustamante, R. T.; Jones, P. G.; Jusko, A.; Kalinak, P.; Kalweit, A.; Kamin, J.; Kang, J. H.; Kaplin, V.; Kar, S.; Karasu Uysal, A.; Karavichev, O.; Karavicheva, T.; Karayan, L.; Karpechev, E.; Kebschull, U.; Keidel, R.; Keijdener, D. L. D.; Keil, M.; Mohisin Khan, M.; Khan, P.; Khan, S. A.; Khanzadeev, A.; Kharlov, Y.; Kileng, B.; Kim, D. W.; Kim, D. J.; Kim, D.; Kim, H.; Kim, J. S.; Kim, M.; Kim, S.; Kim, T.; Kirsch, S.; Kisel, I.; Kiselev, S.; Kisiel, A.; Kiss, G.; Klay, J. L.; Klein, C.; Klein, J.; Klein-Bösing, C.; Klewin, S.; Kluge, A.; Knichel, M. L.; Knospe, A. G.; Kobdaj, C.; Kofarago, M.; Kollegger, T.; Kolojvari, A.; Kondratiev, V.; Kondratyeva, N.; Kondratyuk, E.; Konevskikh, A.; Kopcik, M.; Kostarakis, P.; Kour, M.; Kouzinopoulos, C.; Kovalenko, O.; Kovalenko, V.; Kowalski, M.; Koyithatta Meethaleveedu, G.; Králik, I.; Kravčáková, A.; Kretz, M.; Krivda, M.; Krizek, F.; Kryshen, E.; Krzewicki, M.; Kubera, A. M.; Kučera, V.; Kuhn, C.; Kuijer, P. G.; Kumar, A.; Kumar, J.; Kumar, L.; Kumar, S.; Kurashvili, P.; Kurepin, A.; Kurepin, A. B.; Kuryakin, A.; Kweon, M. J.; Kwon, Y.; La Pointe, S. L.; La Rocca, P.; Ladron de Guevara, P.; Lagana Fernandes, C.; Lakomov, I.; Langoy, R.; Lara, C.; Lardeux, A.; Lattuca, A.; Laudi, E.; Lea, R.; Leardini, L.; Lee, G. R.; Lee, S.; Lehas, F.; Lemmon, R. C.; Lenti, V.; Leogrande, E.; León Monzón, I.; León Vargas, H.; Leoncino, M.; Lévai, P.; Li, S.; Li, X.; Lien, J.; Lietava, R.; Lindal, S.; Lindenstruth, V.; Lippmann, C.; Lisa, M. A.; Ljunggren, H. M.; Lodato, D. F.; Loenne, P. I.; Loginov, V.; Loizides, C.; Lopez, X.; López Torres, E.; Lowe, A.; Luettig, P.; Lunardon, M.; Luparello, G.; Lutz, T. H.; Maevskaya, A.; Mager, M.; Mahajan, S.; Mahmood, S. M.; Maire, A.; Majka, R. D.; Malaev, M.; Maldonado Cervantes, I.; Malinina, L.; Mal'Kevich, D.; Malzacher, P.; Mamonov, A.; Manko, V.; Manso, F.; Manzari, V.; Marchisone, M.; Mareš, J.; Margagliotti, G. V.; Margotti, A.; Margutti, J.; Marín, A.; Markert, C.; Marquard, M.; Martin, N. A.; Martin Blanco, J.; Martinengo, P.; Martínez, M. I.; Martínez García, G.; Martinez Pedreira, M.; Mas, A.; Masciocchi, S.; Masera, M.; Masoni, A.; Massacrier, L.; Mastroserio, A.; Matyja, A.; Mayer, C.; Mazer, J.; Mazzoni, M. A.; McDonald, D.; Meddi, F.; Melikyan, Y.; Menchaca-Rocha, A.; Meninno, E.; Mercado Pérez, J.; Meres, M.; Miake, Y.; Mieskolainen, M. M.; Mikhaylov, K.; Milano, L.; Milosevic, J.; Minervini, L. M.; Mischke, A.; Mishra, A. N.; Miśkowiec, D.; Mitra, J.; Mitu, C. M.; Mohammadi, N.; Mohanty, B.; Molñar, L.; Montaño Zetina, L.; Montes, E.; Moreira de Godoy, D. A.; Moreno, L. A. P.; Moretto, S.; Morreale, A.; Morsch, A.; Muccifora, V.; Mudnic, E.; Mühlheim, D.; Muhuri, S.; Mukherjee, M.; Mulligan, J. D.; Munhoz, M. G.; Munzer, R. H.; Murakami, H.; Murray, S.; Musa, L.; Musinsky, J.; Naik, B.; Nair, R.; Nandi, B. K.; Nania, R.; Nappi, E.; Naru, M. U.; Natal da Luz, H.; Nattrass, C.; Navarro, S. R.; Nayak, K.; Nayak, R.; Nayak, T. K.; Nazarenko, S.; Nedosekin, A.; Nellen, L.; Ng, F.; Nicassio, M.; Niculescu, M.; Niedziela, J.; Nielsen, B. S.; Nikolaev, S.; Nikulin, S.; Nikulin, V.; Noferini, F.; Nomokonov, P.; Nooren, G.; Noris, J. C. C.; Norman, J.; Nyanin, A.; Nystrand, J.; Oeschler, H.; Oh, S.; Oh, S. K.; Ohlson, A.; Okatan, A.; Okubo, T.; Olah, L.; Oleniacz, J.; Oliveira da Silva, A. C.; Oliver, M. H.; Onderwaater, J.; Oppedisano, C.; Orava, R.; Ortiz Velasquez, A.; Oskarsson, A.; Otwinowski, J.; Oyama, K.; Ozdemir, M.; Pachmayer, Y.; Pagano, P.; Paić, G.; Pal, S. K.; Pan, J.; Pandey, A. K.; Papikyan, V.; Pappalardo, G. S.; Pareek, P.; Park, W. J.; Parmar, S.; Passfeld, A.; Paticchio, V.; Patra, R. N.; Paul, B.; Pei, H.; Peitzmann, T.; Pereira da Costa, H.; Peresunko, D.; Pérez Lara, C. E.; Perez Lezama, E.; Peskov, V.; Pestov, Y.; Petráček, V.; Petrov, V.; Petrovici, M.; Petta, C.; Piano, S.; Pikna, M.; Pillot, P.; Pimentel, L. O. D. L.; Pinazza, O.; Pinsky, L.; Piyarathna, D. B.; Płoskoń, M.; Planinic, M.; Pluta, J.; Pochybova, S.; Podesta-Lerma, P. L. M.; Poghosyan, M. G.; Polichtchouk, B.; Poljak, N.; Poonsawat, W.; Pop, A.; Porteboeuf-Houssais, S.; Porter, J.; Pospisil, J.; Prasad, S. K.; Preghenella, R.; Prino, F.; Pruneau, C. A.; Pshenichnov, I.; Puccio, M.; Puddu, G.; Pujahari, P.; Punin, V.; Putschke, J.; Qvigstad, H.; Rachevski, A.; Raha, S.; Rajput, S.; Rak, J.; Rakotozafindrabe, A.; Ramello, L.; Rami, F.; Raniwala, R.; Raniwala, S.; Räsänen, S. S.; Rascanu, B. T.; Rathee, D.; Read, K. F.; Redlich, K.; Reed, R. J.; Rehman, A.; Reichelt, P.; Reidt, F.; Ren, X.; Renfordt, R.; Reolon, A. R.; Reshetin, A.; Revol, J.-P.; Reygers, K.; Riabov, V.; Ricci, R. A.; Richert, T.; Richter, M.; Riedler, P.; Riegler, W.; Riggi, F.; Ristea, C.; Rocco, E.; Rodríguez Cahuantzi, M.; Rodriguez Manso, A.; Røed, K.; Rogochaya, E.; Rohr, D.; Röhrich, D.; Romita, R.; Ronchetti, F.; Ronflette, L.; Rosnet, P.; Rossi, A.; Roukoutakis, F.; Roy, A.; Roy, C.; Roy, P.; Rubio Montero, A. J.; Rui, R.; Russo, R.; Ryabinkin, E.; Ryabov, Y.; Rybicki, A.; Sadovsky, S.; Šafařík, K.; Sahlmuller, B.; Sahoo, P.; Sahoo, R.; Sahoo, S.; Sahu, P. K.; Saini, J.; Sakai, S.; Saleh, M. A.; Salzwedel, J.; Sambyal, S.; Samsonov, V.; Šándor, L.; Sandoval, A.; Sano, M.; Sarkar, D.; Sarma, P.; Scapparone, E.; Scarlassara, F.; Schiaua, C.; Schicker, R.; Schmidt, C.; Schmidt, H. R.; Schuchmann, S.; Schukraft, J.; Schulc, M.; Schuster, T.; Schutz, Y.; Schwarz, K.; Schweda, K.; Scioli, G.; Scomparin, E.; Scott, R.; Šefčík, M.; Seger, J. E.; Sekiguchi, Y.; Sekihata, D.; Selyuzhenkov, I.; Senosi, K.; Senyukov, S.; Serradilla, E.; Sevcenco, A.; Shabanov, A.; Shabetai, A.; Shadura, O.; Shahoyan, R.; Shahzad, M. I.; Shangaraev, A.; Sharma, A.; Sharma, M.; Sharma, M.; Sharma, N.; Shigaki, K.; Shtejer, K.; Sibiriak, Y.; Siddhanta, S.; Sielewicz, K. M.; Siemiarczuk, T.; Silvermyr, D.; Silvestre, C.; Simatovic, G.; Simonetti, G.; Singaraju, R.; Singh, R.; Singha, S.; Singhal, V.; Sinha, B. C.; Sinha, T.; Sitar, B.; Sitta, M.; Skaali, T. B.; Slupecki, M.; Smirnov, N.; Snellings, R. J. M.; Snellman, T. W.; Søgaard, C.; Song, J.; Song, M.; Song, Z.; Soramel, F.; Sorensen, S.; de Souza, R. D.; Sozzi, F.; Spacek, M.; Spiriti, E.; Sputowska, I.; Spyropoulou-Stassinaki, M.; Stachel, J.; Stan, I.; Stankus, P.; Stefanek, G.; Stenlund, E.; Steyn, G.; Stiller, J. H.; Stocco, D.; Strmen, P.; Suaide, A. A. P.; Sugitate, T.; Suire, C.; Suleymanov, M.; Suljic, M.; Sultanov, R.; Šumbera, M.; Szabo, A.; Szanto de Toledo, A.; Szarka, I.; Szczepankiewicz, A.; Szymanski, M.; Tabassam, U.; Takahashi, J.; Tambave, G. J.; Tanaka, N.; Tangaro, M. A.; Tarhini, M.; Tariq, M.; Tarzila, M. G.; Tauro, A.; Tejeda Muñoz, G.; Telesca, A.; Terasaki, K.; Terrevoli, C.; Teyssier, B.; Thäder, J.; Thomas, D.; Tieulent, R.; Timmins, A. R.; Toia, A.; Trogolo, S.; Trombetta, G.; Trubnikov, V.; Trzaska, W. H.; Tsuji, T.; Tumkin, A.; Turrisi, R.; Tveter, T. S.; Ullaland, K.; Uras, A.; Usai, G. L.; Utrobicic, A.; Vajzer, M.; Vala, M.; Valencia Palomo, L.; Vallero, S.; van der Maarel, J.; van Hoorne, J. W.; van Leeuwen, M.; Vanat, T.; Vande Vyvre, P.; Varga, D.; Vargas, A.; Vargyas, M.; Varma, R.; Vasileiou, M.; Vasiliev, A.; Vauthier, A.; Vechernin, V.; Veen, A. M.; Veldhoen, M.; Velure, A.; Venaruzzo, M.; Vercellin, E.; Vergara Limón, S.; Vernet, R.; Verweij, M.; Vickovic, L.; Viesti, G.; Viinikainen, J.; Vilakazi, Z.; Villalobos Baillie, O.; Villatoro Tello, A.; Vinogradov, A.; Vinogradov, L.; Vinogradov, Y.; Virgili, T.; Vislavicius, V.; Viyogi, Y. P.; Vodopyanov, A.; Völkl, M. A.; Voloshin, K.; Voloshin, S. A.; Volpe, G.; von Haller, B.; Vorobyev, I.; Vranic, D.; Vrláková, J.; Vulpescu, B.; Wagner, B.; Wagner, J.; Wang, H.; Wang, M.; Watanabe, D.; Watanabe, Y.; Weber, M.; Weber, S. G.; Weiser, D. F.; Wessels, J. P.; Westerhoff, U.; Whitehead, A. M.; Wiechula, J.; Wikne, J.; Wilk, G.; Wilkinson, J.; Williams, M. C. S.; Windelband, B.; Winn, M.; Yang, H.; Yang, P.; Yano, S.; Yasin, Z.; Yin, Z.; Yokoyama, H.; Yoo, I.-K.; Yoon, J. H.; Yurchenko, V.; Yushmanov, I.; Zaborowska, A.; Zaccolo, V.; Zaman, A.; Zampolli, C.; Zanoli, H. J. C.; Zaporozhets, S.; Zardoshti, N.; Zarochentsev, A.; Závada, P.; Zaviyalov, N.; Zbroszczyk, H.; Zgura, I. S.; Zhalov, M.; Zhang, H.; Zhang, X.; Zhang, Y.; Zhang, C.; Zhang, Z.; Zhao, C.; Zhigareva, N.; Zhou, D.; Zhou, Y.; Zhou, Z.; Zhu, H.; Zhu, J.; Zichichi, A.; Zimmermann, A.; Zimmermann, M. B.; Zinovjev, G.; Zyzak, M.; Alice Collaboration

    2016-05-01

    Three- and four-pion Bose-Einstein correlations are presented in p p ,p -Pb, and Pb-Pb collisions at the LHC. We compare our measured four-pion correlations to the expectation derived from two- and three-pion measurements. Such a comparison provides a method to search for coherent pion emission. We also present mixed-charge correlations in order to demonstrate the effectiveness of several analysis procedures such as Coulomb corrections. Same-charge four-pion correlations in p p and p -Pb appear consistent with the expectations from three-pion measurements. However, the presence of non-negligible background correlations in both systems prevent a conclusive statement. In Pb-Pb collisions, we observe a significant suppression of three- and four-pion Bose-Einstein correlations compared to expectations from two-pion measurements. There appears to be no centrality dependence of the suppression within the 0%-50% centrality interval. The origin of the suppression is not clear. However, by postulating either coherent pion emission or large multibody Coulomb effects, the suppression may be explained.

  6. Multipion Bose-Einstein correlations in p p , p -Pb, and Pb-Pb collisions at energies available at the CERN Large Hadron Collider

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Adam, J.; Adamová, D.; Aggarwal, M. M.

    Three- and four-pion Bose-Einstein correlations are presented in pp,p-Pb, and Pb-Pb collisions at the LHC. We compare our measured four-pion correlations to the expectation derived from two- and three-pion measurements. Such a comparison provides a method to search for coherent pion emission. We also present mixed-charge correlations in order to demonstrate the effectiveness of several analysis procedures such as Coulomb corrections. Same-charge four-pion correlations in pp and p-Pb appear consistent with the expectations from three-pion measurements. However, the presence of non-negligible background correlations in both systems prevent a conclusive statement. In Pb-Pb collisions, we observe a significant suppression of three-more » and four-pion Bose-Einstein correlations compared to expectations from two-pion measurements. There appears to be no centrality dependence of the suppression within the 0%-50% centrality interval. The origin of the suppression is not clear. However, by postulating either coherent pion emission or large multibody Coulomb effects, the suppression may be explained.« less

  7. Multipion Bose-Einstein correlations in p p , p -Pb, and Pb-Pb collisions at energies available at the CERN Large Hadron Collider

    DOE PAGES

    Adam, J.; Adamová, D.; Aggarwal, M. M.; ...

    2016-05-18

    Three- and four-pion Bose-Einstein correlations are presented in pp,p-Pb, and Pb-Pb collisions at the LHC. We compare our measured four-pion correlations to the expectation derived from two- and three-pion measurements. Such a comparison provides a method to search for coherent pion emission. We also present mixed-charge correlations in order to demonstrate the effectiveness of several analysis procedures such as Coulomb corrections. Same-charge four-pion correlations in pp and p-Pb appear consistent with the expectations from three-pion measurements. However, the presence of non-negligible background correlations in both systems prevent a conclusive statement. In Pb-Pb collisions, we observe a significant suppression of three-more » and four-pion Bose-Einstein correlations compared to expectations from two-pion measurements. There appears to be no centrality dependence of the suppression within the 0%-50% centrality interval. The origin of the suppression is not clear. However, by postulating either coherent pion emission or large multibody Coulomb effects, the suppression may be explained.« less

  8. Three Axis Control of the Hubble Space Telescope Using Two Reaction Wheels and Magnetic Torquer Bars for Science Observations

    NASA Technical Reports Server (NTRS)

    Hur-Diaz, Sun; Wirzburger, John; Smith, Dan

    2008-01-01

    The Hubble Space Telescope (HST) is renowned for its superb pointing accuracy of less than 10 milli-arcseconds absolute pointing error. To accomplish this, the HST relies on its complement of four reaction wheel assemblies (RWAs) for attitude control and four magnetic torquer bars (MTBs) for momentum management. As with most satellites with reaction wheel control, the fourth RWA provides for fault tolerance to maintain three-axis pointing capability should a failure occur and a wheel is lost from operations. If an additional failure is encountered, the ability to maintain three-axis pointing is jeopardized. In order to prepare for this potential situation, HST Pointing Control Subsystem (PCS) Team developed a Two Reaction Wheel Science (TRS) control mode. This mode utilizes two RWAs and four magnetic torquer bars to achieve three-axis stabilization and pointing accuracy necessary for a continued science observing program. This paper presents the design of the TRS mode and operational considerations necessary to protect the spacecraft while allowing for a substantial science program.

  9. Evaluation of swabs and transport media for the recovery of ...

    EPA Pesticide Factsheets

    Journal Article Two Y. pestis strains (virulent and avirulent), four swab types (polyester, macrofoam, rayon, and cotton), two pre-moistening solutions, six transport media, three temperatures, two levels of organic load, and four processing methods were evaluated to determine the conditions that would yield the highest percent of cultivable Y. pestis cells after storage.

  10. Alcohol Use Screening

    MedlinePlus

    ... an interactive version of this tool. Select your gender. Female Male How often do you have a drink containing alcohol? Never Monthly or Less Two to four times a month Two to Three Times a Week Four or more times a week How many drinks containing alcohol do you have on a ...

  11. Crash Models For Rural Intersections: Four-Lane By Two-Lane Stop-Controlled And Two-Lane By Two-Lane Signalized

    DOT National Transportation Integrated Search

    1999-10-01

    This report describes the collection, analysis, and modeling of crash and roadway data for intersections on rural roads in California and Michigan for the years 1993-1995. Three classes of intersections are considered: (1) three-legged intersections ...

  12. Family Size, Interaction, Affect and Stress

    ERIC Educational Resources Information Center

    Nye, F. Ivan; And Others

    1970-01-01

    Synthesizes previous research on relationship of family size to attitudes. Reduces findings to four propositions and submits these propositions to additional tests utilizing secondary data from two large surveys. Substantively, families of three or four children rank lower in all of the analyses than do families with one or two children. Presented…

  13. Avalanche of entanglement and correlations at quantum phase transitions.

    PubMed

    Krutitsky, Konstantin V; Osterloh, Andreas; Schützhold, Ralf

    2017-06-16

    We study the ground-state entanglement in the quantum Ising model with nearest neighbor ferromagnetic coupling J and find a sequential increase of entanglement depth d with growing J. This entanglement avalanche starts with two-point entanglement, as measured by the concurrence, and continues via the three-tangle and four-tangle, until finally, deep in the ferromagnetic phase for J = ∞, arriving at a pure L-partite (GHZ type) entanglement of all L spins. Comparison with the two, three, and four-point correlations reveals a similar sequence and shows strong ties to the above entanglement measures for small J. However, we also find a partial inversion of the hierarchy, where the four-point correlation exceeds the three- and two-point correlations, well before the critical point is reached. Qualitatively similar behavior is also found for the Bose-Hubbard model, suggesting that this is a general feature of a quantum phase transition. This should be taken into account in the approximations starting from a mean-field limit.

  14. Experimental design for three-color and four-color gene expression microarrays.

    PubMed

    Woo, Yong; Krueger, Winfried; Kaur, Anupinder; Churchill, Gary

    2005-06-01

    Three-color microarrays, compared with two-color microarrays, can increase design efficiency and power to detect differential expression without additional samples and arrays. Furthermore, three-color microarray technology is currently available at a reasonable cost. Despite the potential advantages, clear guidelines for designing and analyzing three-color experiments do not exist. We propose a three- and a four-color cyclic design (loop) and a complementary graphical representation to help design experiments that are balanced, efficient and robust to hybridization failures. In theory, three-color loop designs are more efficient than two-color loop designs. Experiments using both two- and three-color platforms were performed in parallel and their outputs were analyzed using linear mixed model analysis in R/MAANOVA. These results demonstrate that three-color experiments using the same number of samples (and fewer arrays) will perform as efficiently as two-color experiments. The improved efficiency of the design is somewhat offset by a reduced dynamic range and increased variability in the three-color experimental system. This result suggests that, with minor technological improvements, three-color microarrays using loop designs could detect differential expression more efficiently than two-color loop designs. http://www.jax.org/staff/churchill/labsite/software Multicolor cyclic design construction methods and examples along with additional results of the experiment are provided at http://www.jax.org/staff/churchill/labsite/pubs/yong.

  15. Contrasting the effects of duration and number of syllables on the perceptual normalization of lexical tones

    NASA Astrophysics Data System (ADS)

    Ciocca, Valter; Francis, Alexander L.; Yau, Teresa S.-K.

    2004-05-01

    In tonal languages, syllabic fundamental frequency (F0) patterns (``lexical tones'') convey lexical meaning. Listeners need to relate such pitch patterns to the pitch range of a speaker (``tone normalization'') to accurately identify lexical tones. This study investigated the amount of tonal information required to perform tone normalization. A target CV syllable, perceived as either a high level, a low level, or a mid level Cantonese tone, was preceded by a four-syllable carrier sentence whose F0 was shifted (1 semitone), or not shifted. Four conditions were obtained by gating one, two, three, or four syllables from the onset of the target. Presentation rate (normal versus fast) was set such that the duration of the one, two, and three syllable conditions (normal carrier) was equal to that of the two, three, and four syllable conditions (fast carrier). Results suggest that tone normalization is largely accomplished within 250 ms or so prior to target onset, independent of the number of syllables; additional tonal information produces a relatively small increase in tone normalization. Implications for models of lexical tone normalization will be discussed. [Work supported by the RGC of the Hong Kong SAR, Project No. HKU 7193/00H.

  16. Optical and structural characterization of InAs/GaAs quantum wells

    NASA Technical Reports Server (NTRS)

    Ksendzov, A.; George, T.; Grunthaner, F. J.; Liu, J. K.; Rich, D. H.; Terhune, R. W.; Wilson, B. A.; Pollak, F. H.; Huang, Y.-S.

    1991-01-01

    Three InAs/GaAs single quantum wells of two-, three-, and four-monolayer thickness were characterized using optical and structural techniques. The results of high-resolution transmission electron (HRTEM) microscopy and optical studies which combine absorption, photoluminescence (PL), photoreflectance, and cathodoluminescence are presented. Using the polarization modulated absorptance technique, we observed two absorption features in our samples at 77 K. On the basis of their polarization properties and comparison with an envelope function calculation, these structures are assigned to transitions between the confined heavy-hole and confined and unconfined electron levels. Photoreflectance spectra of the three-monolayer sample in 77-300 K range show only the fundamental quantum well transition. The temperature dependence of this transition is approximately linear with a slope of 2.2 x 10 exp -4 eV/K, which is significantly lower than in both constituent materials. Comparison to the absorption data reveals that the PL spectra are affected by the carrier diffusion and therefore do not provide direct measure of the exciton density of states. The HRTEM images indicate that, while the interfaces of the two-monolayer sample are smooth and the well thickness is uniform, the four-monolayer sample has uneven interfaces and contains domains of two, three, and four monolayers.

  17. COSMOS-e'-soft Higgsotic attractors

    NASA Astrophysics Data System (ADS)

    Choudhury, Sayantan

    2017-07-01

    In this work, we have developed an elegant algorithm to study the cosmological consequences from a huge class of quantum field theories (i.e. superstring theory, supergravity, extra dimensional theory, modified gravity, etc.), which are equivalently described by soft attractors in the effective field theory framework. In this description we have restricted our analysis for two scalar fields - dilaton and Higgsotic fields minimally coupled with Einstein gravity, which can be generalized for any arbitrary number of scalar field contents with generalized non-canonical and non-minimal interactions. We have explicitly used R^2 gravity, from which we have studied the attractor and non-attractor phases by exactly computing two point, three point and four point correlation functions from scalar fluctuations using the In-In (Schwinger-Keldysh) and the δ N formalisms. We have also presented theoretical bounds on the amplitude, tilt and running of the primordial power spectrum, various shapes (equilateral, squeezed, folded kite or counter-collinear) of the amplitude as obtained from three and four point scalar functions, which are consistent with observed data. Also the results from two point tensor fluctuations and the field excursion formula are explicitly presented for the attractor and non-attractor phase. Further, reheating constraints, scale dependent behavior of the couplings and the dynamical solution for the dilaton and Higgsotic fields are also presented. New sets of consistency relations between two, three and four point observables are also presented, which shows significant deviation from canonical slow-roll models. Additionally, three possible theoretical proposals have presented to overcome the tachyonic instability at the time of late time acceleration. Finally, we have also provided the bulk interpretation from the three and four point scalar correlation functions for completeness.

  18. Use of Parsimony Analysis to Identify Areas of Endemism of Chinese Birds: Implications for Conservation and Biogeography

    PubMed Central

    Huang, Xiao-Lei; Qiao, Ge-Xia; Lei, Fu-Min

    2010-01-01

    Parsimony analysis of endemicity (PAE) was used to identify areas of endemism (AOEs) for Chinese birds at the subregional level. Four AOEs were identified based on a distribution database of 105 endemic species and using 18 avifaunal subregions as the operating geographical units (OGUs). The four AOEs are the Qinghai-Zangnan Subregion, the Southwest Mountainous Subregion, the Hainan Subregion and the Taiwan Subregion. Cladistic analysis of subregions generally supports the division of China’s avifauna into Palaearctic and Oriental realms. Two PAE area trees were produced from two different distribution datasets (year 1976 and 2007). The 1976 topology has four distinct subregional branches; however, the 2007 topology has three distinct branches. Moreover, three Palaearctic subregions in the 1976 tree clustered together with the Oriental subregions in the 2007 tree. Such topological differences may reflect changes in the distribution of bird species through circa three decades. PMID:20559504

  19. The many faces of intestinal tract gastric heterotopia; a series of four cases highlighting clinical and pathological heterogeneity.

    PubMed

    Nasir, Aqsa; Amateau, Stuart K; Khan, Sabina; Simpson, Ross W; Snover, Dale C; Amin, Khalid

    2018-04-01

    Gastric heterotopia of the intestinal tract can have a diverse clinicopathologic presentation, resulting in a diagnostic dilemma. We present a series of four cases, two male and two female patients with age range of 31-82 years, found in the duodenum, jejunum, and transverse colon. The most common and rather unusual clinical presentation was iron deficiency anemia, seen in three cases, while one patient presented with abdominal pain. Endoscopically, two cases were visualized as pedunculated polyps and two as sessile/plaque-like lesions. Polypectomy was performed in three patients, and one patient underwent biopsy followed by resection. Two cases showed oxyntic-type epithelium, and two cases exhibited pyloric-type gastric epithelium. Three patients were relieved of their presenting symptoms after therapeutic procedures with no evidence of recurrence noted on follow-up. Follow-up was not available on one patient. This case series highlights a diverse clinicopathologic spectrum of gastric heterotopia. Accurate diagnosis is essential for proper management. Copyright © 2018. Published by Elsevier Inc.

  20. Life cycle of the multiarmed sea star Coscinasterias acutispina (Stimpson, 1862) in laboratory culture: sexual and asexual reproductive pathways.

    PubMed

    Shibata, Daisuke; Hirano, Yoshiaki; Komatsu, Miéko

    2011-05-01

    The multiarmed sea star Coscinasterias acutispina generally has 7-10 arms and 2-5 madreporites. It is known to be able to reproduce by asexual fission, and we have previously observed that this species also has the ability to reproduce sexually; however, there has been no report until now of spawning in this species. We succeeded in establishing a long-term culture of juveniles produced by artificial fertilization. Twelve months after the completion of metamorphosis, three individuals had six arms of the same length and a madreporite. At this time, fission occurred in two of these individuals, while the remaining individual underwent fission four months later. Each sea star divided into two halves, provided with three arms each. Thereafter, four or five new arms and two or four madreporites were formed anew in each of the six daughter sea-stars, so that by 30 days after the first fission the number of arms and madreporites in each was similar to that in adults. A second fission occurred in four of these six individuals, four or five months after the first fission, and in three of them the plane of division was the same as that of the first fission. The original three individuals eventually proliferated to 12 by undergoing fission. All individuals had fully developed gonads by 1-3 months after the second fission. Some of them eventually spawned under laboratory culture, and the resulting larvae metamorphosed into juveniles. Our observations demonstrate that individuals of C. acutispina possess the potential for both sexual and asexual reproduction.

  1. Calculation of unsteady aerodynamics for four AGARD standard aeroelastic configurations

    NASA Technical Reports Server (NTRS)

    Bland, S. R.; Seidel, D. A.

    1984-01-01

    Calculated unsteady aerodynamic characteristics for four Advisory Group for Aeronautical Research Development (AGARD) standard aeroelastic two-dimensional airfoils and for one of the AGARD three-dimensional wings are reported. Calculations were made using the finite-difference codes XTRAN2L (two-dimensional flow) and XTRAN3S (three-dimensional flow) which solve the transonic small disturbance potential equations. Results are given for the 36 AGARD cases for the NACA 64A006, NACA 64A010, and NLR 7301 airfoils with experimental comparisons for most of these cases. Additionally, six of the MBB-A3 airfoil cases are included. Finally, results are given for three of the cases for the rectangular wing.

  2. The role of ultrasound in the management of flexor tendon injuries.

    PubMed

    Jeyapalan, K; Bisson, M A; Dias, J J; Griffin, Y; Bhatt, R

    2008-08-01

    The use of ultrasound scanning to establish tendon pathologies was assessed retrospectively in 17 patients in 18 digits. The ultrasound scan demonstrated four patterns: (1) normal intact tendons in four, (2) ruptured tendons in three, (3) tendons in continuity but attenuated in five and (4) tendons in continuity but thickened with fibrosis and decreased movement representing adhesions in five patients. Surgery was undertaken in only three cases, confirming the ultrasound diagnosis in two. Surgery was offered to all three patients with ruptures but was declined by two. Ultrasound imaging helped to avoid surgery in 14 cases by excluding flexor tendon re-ruptures. This allowed on-going mobilisation, leading to recovery of function.

  3. A comparative study on pathological features of transgenic rat lines expressing either three or four repeat misfolded tau.

    PubMed

    Valachova, Bernadeta; Brezovakova, Veronika; Bugos, Ondrej; Jadhav, Santosh; Smolek, Tomas; Novak, Petr; Zilka, Norbert

    2018-08-01

    Human tauopathies represent a heterogeneous group of neurodegenerative disorders characterized by distinct clinical features, typical histopathological structures, and defined ratio(s) of three-repeat and four-repeat tau isoforms within pathological aggregates. How the optional microtubule-binding repeat of tau influences this differentiation of pathologies is understudied. We have previously generated and characterized transgenic rodent models expressing human truncated tau aa151-391 with either three (SHR24) or four microtubule-binding repeats (SHR72). Here, we compare the behavioral and neuropathological hallmarks of these two transgenic lines using a battery of tests for sensorimotor, cognitive, and neurological functions over the age range of 3.5-15 months. Progression of sensorimotor and neurological deficits was similar in both transgenic lines; however, the lifespan of transgenic line SHR72 expressing truncated four-repeat tau was markedly shorter than SHR24. Moreover, the expression of three or four-repeat tau induced distinct neurofibrillary pathology in these lines. Transgenic lines displayed different distribution of tau pathology and different type of neurofibrillary tangles. Our results suggest that three- and four-repeat isoforms of tau may display different modes of action in the diseased brain. © 2018 Wiley Periodicals, Inc.

  4. Probing a four flavor vis-a-vis three flavor neutrino mixing for ultrahigh energy neutrino signals at a 1 km2 detector

    NASA Astrophysics Data System (ADS)

    Pandey, Madhurima; Majumdar, Debasish; Dutta Banik, Amit

    2018-05-01

    We consider a four-flavor scenario for the neutrinos where an extra sterile neutrino is introduced to the three families of active neutrinos and study the deviation from the three-flavor scenario in the ultrahigh-energy (UHE) regime. We calculate the possible muon and shower yields at a 1 km2 detector such as IceCube for these neutrinos from distant UHE sources, e.g., gamma-ray bursts, etc. Similar estimations for muon and shower yields are also obtained for the three-flavor case. Comparing the two results, we find considerable differences between the yields for these two cases. This can be useful for probing the existence of a fourth sterile component using UHE neutrino flux.

  5. Entropy and temperature from black-hole/near-horizon-CFT duality

    NASA Astrophysics Data System (ADS)

    Rodriguez, Leo; Yildirim, Tuna

    2010-08-01

    We construct a two-dimensional CFT, in the form of a Liouville theory, in the near-horizon limit of four- and three-dimensional black holes. The near-horizon CFT assumes two-dimensional black hole solutions first introduced by Christensen and Fulling (1977 Phys. Rev. D 15 2088-104) and expanded to a greater class of black holes via Robinson and Wilczek (2005 Phys. Rev. Lett. 95 011303). The two-dimensional black holes admit a Diff(S1) subalgebra, which upon quantization in the horizon limit becomes Virasoro with calculable central charge. This charge and the lowest Virasoro eigen-mode reproduce the correct Bekenstein-Hawking entropy of the four- and three-dimensional black holes via the known Cardy formula (Blöte et al 1986 Phys. Rev. Lett. 56 742; Cardy 1986 Nucl. Phys. B 270 186). Furthermore, the two-dimensional CFT's energy-momentum tensor is anomalous. However, in the horizon limit the energy-momentum tensor becomes holomorphic equaling the Hawking flux of the four- and three-dimensional black holes. This encoding of both entropy and temperature provides a uniformity in the calculation of black hole thermodynamic and statistical quantities for the non-local effective action approach.

  6. Hierarchical Controlled Remote State Preparation by Using a Four-Qubit Cluster State

    NASA Astrophysics Data System (ADS)

    Ma, Peng-Cheng; Chen, Gui-Bin; Li, Xiao-Wei; Zhan, You-Bang

    2018-06-01

    We propose a scheme for hierarchical controlled remote preparation of an arbitrary single-qubit state via a four-qubit cluster state as the quantum channel. In this scheme, a sender wishes to help three agents to remotely prepare a quantum state, respectively. The three agents are divided into two grades, that is, an agent is in the upper grade and other two agents are in the lower grade. In this process of remote state preparation, the agent of the upper grade only needs the assistance of any one of the other two agents for recovering the sender's original state, while an agent of the lower grade needs the collaboration of all the other two agents. In other words, the agents of two grades have different authorities to reconstruct sender's original state.

  7. The Effects of Test Preparation on Second-Language Listening Test Performance

    ERIC Educational Resources Information Center

    Winke, Paula; Lim, Hyojung

    2017-01-01

    To examine the effects of listening test preparation, we had three groups, two experimental and one control (63 learners total), partake in three types of instruction sandwiched between two equally difficult listening tests (pretests and posttests). The first experimental group took four practice tests and received "explicit"…

  8. Innovative strategies for a successful SLMTA country programme: The Rwanda story

    PubMed Central

    Sebasirimu, Sabin; Gatabazi, John B.; Ruzindana, Emmanuel; Kayobotsi, Claver; Linde, Mary K.; Mazarati, Jean B.; Ntagwabira, Edouard; Serumondo, Janvier; Dahourou, Georges A.; Gatei, Wangeci; Muvunyi, Claude M.

    2014-01-01

    Background In 2009, to improve the performance of laboratories and strengthen healthcare systems, the World Health Organization Regional Office for Africa (WHO AFRO) and partners launched two initiatives: a laboratory quality improvement programme called Strengthening Laboratory Management Toward Accreditation (SLMTA), and what is now called the Stepwise Laboratory Quality Improvement Process Towards Accreditation (SLIPTA). Objectives This study describes the achievements of Rwandan laboratories four years after the introduction of SLMTA in the country, using the SLIPTA scoring system to measure laboratory progress. Methods Three cohorts of five laboratories each were enrolled in the SLMTA programme in 2010, 2011 and 2013. The cohorts used SLMTA workshops, improvement projects, mentorship and quarterly performance-based financing incentives to accelerate laboratory quality improvement. Baseline, exit and follow-up audits were conducted over a two-year period from the time of enrolment. Audit scores were used to categorise laboratory quality on a scale of zero (< 55%) to five (95% – 100%) stars. Results At baseline, 14 of the 15 laboratories received zero stars with the remaining laboratory receiving a two-star rating. At exit, five laboratories received one star, six received two stars and four received three stars. At the follow-up audit conducted in the first two cohorts approximately one year after exit, one laboratory scored two stars, five laboratories earned three stars and four laboratories, including the National Reference Laboratory, achieved four stars. Conclusion Rwandan laboratories enrolled in SLMTA showed improvement in quality management systems. Sustaining the gains and further expansion of the SLMTA programme to meet country targets will require continued programme strengthening. PMID:29043189

  9. PROFESSIONAL NEGOTIATION IN EDUCATION--A BARGAINING GAME WITH SUPPLEMENTARY MATERIALS. INSTRUCTOR'S MANUAL. FIRST REVISED EDITION.

    ERIC Educational Resources Information Center

    HORVAT, JOHN J.

    IN AN APPLICATION OF GAME THEORY TO PREPARE PARTICIPATING PERSONNEL FOR EFFECTIVE PROFESSIONAL NEGOTIATION IN EDUCATION, THREE FORMS OF COLLECTIVE BARGAINING ARE SIMULATED--ONE FOR A FOUR- TO EIGHT-HOUR TIME PERIOD, A SECOND FOR A TWO- TO FOUR-DAY TIME PERIOD, AND A THIRD FOR A ONE- TO THREE-WEEK WORKSHOP OR SEMINAR. LONGER FORMS PRESENT MORE…

  10. A survey of ab initio conical intersections for the H+H2 system

    NASA Astrophysics Data System (ADS)

    Halász, Gábor; Vibók, Ágnes; Mebel, Alexander M.; Baer, Michael

    2003-02-01

    In this article we present a survey of the various conical intersections which govern potential transitions between the three lower electronic states for the title molecular system. It was revealed that these three states, for a given fixed HH distance, RHH, usually form four conical intersections: two, between the two lower states and two, between the two upper states. One of the four is the well known equilateral D3h ci and the others are, essentially, C2v cis: One of them is located on the symmetry line perpendicular to the HH axis (just like the D3h ci) and the other two are located on both sides of this symmetry line and in this way form the ci-twins. The study was carried out for four RHH-values, namely, RHH=0.74, 0.5417, 0.52, and 0.4777 Å. It was also established that there exists one single RHH-value designated as R˜HH, located in the interval {0.52, 0.53 Å}, for which all four cis coalesce to become one kind of "super" ci which couples the three states. The numerical study was carried out employing the line integral approach for groups of two and three states. As for the two-state calculations we found that all D3h-cis, at close proximity, are circular (ordinary) Jahn-Teller-type cis, whereas all C2v-cis, at close proximity, are elliptic Jahn-Teller cis [Chem. Phys. Lett 354, 243 (2002)]. Particular attention is given to the 3-state quantization of the nonadiabatic coupling matrix. The quantization is found to be fulfilled in all situations as long as the regions in configuration space are not too far from the relevant cis. In the Discussion and Conclusion we discuss, among other subjects, the possibility to diabatize the adiabatic potential matrix.

  11. Dermatomyositis in five Shetland sheepdogs in the United Kingdom.

    PubMed

    Ferguson, E A; Cerundolo, R; Lloyd, D H; Rest, J; Cappello, R

    2000-02-19

    Five cases of dermatomyositis in four Shetland sheepdog puppies and one adult bitch are described. The dogs all had well-defined patches of scaling, crusting and alopecia over the muzzle, periorbital skin and distal limbs, and the tail, perineum and pinnae were affected in some of them. The affected puppies were all sired by the same stud dog. The affected adult bitch was unrelated to the puppies. Three of the four dogs tested had high serum creatine kinase concentrations and electromyographic abnormalities were detected in three of the four dogs tested. The histological changes observed in the skin of four of the dogs strongly supported the diagnosis of dermatomyositis, and in the fifth dog they were compatible with this diagnosis. Two of the puppies were euthanised shortly after being diagnosed. In the other two puppies and the adult the disease remains stable and non-progressive 15 to 18 months after diagnosis. The sire of the four affected puppies has been used extensively because it was considered to be genetically clear of collie eye anomaly.

  12. Emergent fuzzy geometry and fuzzy physics in four dimensions

    NASA Astrophysics Data System (ADS)

    Ydri, Badis; Rouag, Ahlam; Ramda, Khaled

    2017-03-01

    A detailed Monte Carlo calculation of the phase diagram of bosonic mass-deformed IKKT Yang-Mills matrix models in three and six dimensions with quartic mass deformations is given. Background emergent fuzzy geometries in two and four dimensions are observed with a fluctuation given by a noncommutative U (1) gauge theory very weakly coupled to normal scalar fields. The geometry, which is determined dynamically, is given by the fuzzy spheres SN2 and SN2 × SN2 respectively. The three and six matrix models are effectively in the same universality class. For example, in two dimensions the geometry is completely stable, whereas in four dimensions the geometry is stable only in the limit M ⟶ ∞, where M is the mass of the normal fluctuations. The behaviors of the eigenvalue distribution in the two theories are also different. We also sketch how we can obtain a stable fuzzy four-sphere SN2 × SN2 in the large N limit for all values of M as well as models of topology change in which the transition between spheres of different dimensions is observed. The stable fuzzy spheres in two and four dimensions act precisely as regulators which is the original goal of fuzzy geometry and fuzzy physics. Fuzzy physics and fuzzy field theory on these spaces are briefly discussed.

  13. Crystal structure of four-stranded Oxytricha telomeric DNA

    NASA Technical Reports Server (NTRS)

    Kang, C.; Zhang, X.; Ratliff, R.; Moyzis, R.; Rich, A.

    1992-01-01

    The sequence d(GGGGTTTTGGGG) from the 3' overhang of the Oxytricha telomere has been crystallized and its three-dimensional structure solved to 2.5 A resolution. The oligonucleotide forms hairpins, two of which join to make a four-stranded helical structure with the loops containing four thymine residues at either end. The guanine residues are held together by cyclic hydrogen bonding and an ion is located in the centre. The four guanine residues in each segment have a glycosyl conformation that alternates between anti and syn. There are two four-stranded molecules in the asymmetric unit showing that the structure has some intrinsic flexibility.

  14. Composite rogue waves and modulation instability for the three-coupled Hirota system in an optical fiber

    NASA Astrophysics Data System (ADS)

    Chai, Han-Peng; Tian, Bo; Chai, Jun; Du, Zhong

    2017-10-01

    We investigate the three-coupled Hirota system, which is applied to model the long distance communication and ultrafast signal routing systems governing the propagation of light pulses. With the aid of the Darboux dressing transformation, composite rogue wave solutions are derived. Spatial-temporal structures, including the four-petaled structure for the three-coupled Hirota system, are exhibited. We find that the four-petaled rogue waves occur in two of the three components, whereas the eye-shaped rogue wave occurs in the other one. The composite rogue waves can split up into two or three single rogue waves. The corresponding conditions for the occurrence of such phenomena are discussed and presented. We find that the relative position of every single rogue wave is influenced by the ratios of certain parameters. Besides, the linear instability analysis is performed, and our results agree with those from the baseband modulation instability theory.

  15. Three rooted, four canalled mandibular first molar (Radix Entomolaris).

    PubMed

    Parolia, Abhishek; Kundabala, M; Thomas, M S; Mohan, M; Joshi, N

    2009-01-01

    A mandibular first molar with two distal roots is an interesting example of anatomic variation. This paper describes case reports of mandibular first molar with three roots (one mesial and two distal) and four canals (two in mesial and one in each distobuccal and distolingual root). The canals were shaped with protaper rotary files and irrigated with 5.25% sodium hyochlorite, 0.2 %w/v of chlorhexidine gluconate and normal saline as the fi nal irrigant. The canals were then obturated with gutta- percha and AH plus sealer. These case reports show an anatomic variation of internal morphology of the tooth and points out the importance of searching for additional canals.

  16. Implementation of curing, texturing, subbase, and compaction measurement alternatives for continuously reinforced concrete pavement.

    DOT National Transportation Integrated Search

    2014-04-01

    This report evaluates four different subbase types, two different concrete mix designs (a standard Texas : Department of Transportation gradation and an optimized gradation), three different curing compounds, and : four different surface textures tha...

  17. After Two Years, Three Elementary Math Curricula Outperform a Fourth. NCEE Evaluation Brief. NCEE 2013-4019

    ERIC Educational Resources Information Center

    Agodini, Roberto; Harris, Barbara; Seftor, Neil; Remillard, Janine; Thomas, Melissa

    2013-01-01

    This brief aims to help educators understand the implications of math curriculum choice in the early elementary grades by presenting new findings from a study that examined how four math curricula affect students' achievement across two years--from 1st through 2nd grades. The four curricula were (1) Investigations in Number, Data, and Space…

  18. Hierarchically controlled remote preparation of an arbitrary single-qubit state by using a four-qubit |χ > entangled state

    NASA Astrophysics Data System (ADS)

    Ma, Peng-Cheng; Chen, Gui-Bin; Li, Xiao-Wei; Zhan, You-Bang

    2018-05-01

    In this paper, we present a scheme for Hierarchically controlled remote preparation of an arbitrary single-qubit state via a four-qubit |χ > state as the quantum channel. In this scheme, a sender wishes to help three agents to remotely prepare a quantum state, respectively. The three agents are divided into two grades, that is, an agent is in the upper grade and other two agents are in the lower grade. It is shown that the agent of the upper grade only needs the assistance of any one of the other two agents for recovering the sender's original state, while an agent of the lower grade needs the collaboration of all the other two agents. In other words, the agents of two grades have different authorities to recover sender's original state.

  19. EXCESS CANCER MORTALITY IN AGRICULTURAL REGIONS OF MINNESOTA

    EPA Science Inventory

    Because of its unique geology, Minnesota can be divided into four agricultural regions: south-central region one (corn, soybeans); west-central region two (wheat, corn, soybeans); northwest region three (wheat, sugar beets, potatoes); and northeast region four (forested and urban...

  20. When is four far more than three? Children's generalization of newly acquired number words.

    PubMed

    Huang, Yi Ting; Spelke, Elizabeth; Snedeker, Jesse

    2010-04-01

    What is the relationship between children's first number words and number concepts? We used training tasks to explore children's interpretation of number words as they acquired the words' meanings. Children who had mastered the meanings of only the first two or three number words were systematically provided with varied input on the next word-to-quantity mapping, and their extension of the newly trained word was assessed across a variety of test items. Children who had already mastered number words to three generalized training on four to new objects and nouns, such that their representation of the newly learned number was approximate. In contrast, children who had mastered only one and two learned to apply three reliably within a single count-noun context (e.g., three dogs), but did not generalize training to new objects labeled with different nouns (e.g., three cows). Both findings suggest that children fail to map newly learned words in their counting routine to the fully abstract concepts of natural numbers.

  1. Sensing the Sea: A Curriculum Guide in Marine Education for Grades Two and Three.

    ERIC Educational Resources Information Center

    Odell-Fisher, Ellen; Giese, Ronald N.

    This is a curriculum guide in marine education for grades two and three. It gives information for the setup and maintenance of marine aquariums, as well as information on the care and feeding of marine animals. The unit should take about three or four weeks. A calendar is given showing the amount of time needed for each part. The guide is divided…

  2. Clinical study of concurrent chemoradiotherapy or radiotherapy alone for esophageal cancer patients with positive lymph node metastasis.

    PubMed

    Han, Jihua; Zhu, Weiguo; Yu, Changhua; Zhou, Xilei; Li, Tao; Zhang, Xiaoye

    2012-01-01

    Esophageal cancer patients with pathologic lymph node involvement generally have a poor prognosis. Many randomized controlled trials have not achieved consistent results similar to those of the RTOG8501 trial, and the long-term survival rate has not increased. The present study aimed to compare the efficacy and toxic side effects of concurrent chemoradiotherapy and radiotherapy alone to treat N1 esophageal carcinoma. A total of 130 N1 esophageal carcinoma patients were enrolled and randomly divided into two groups: concurrent chemoradiotherapy group (n = 65) and radiotherapy group (n = 65). Both groups received three-dimensional conformal radiotherapy with a total dose of 64-66 Gy. Meanwhile, to the concurrent chemoradiotherapy group, an additional chemotherapy protocol (nedaplatin, 20 mg/m²/d, 5-FU, 500 mg/m²/d for four days) was given from day 1, and such treatment was repeated until day 29. From day 21 after radiotherapy, two cycles of a consolidated chemotherapy protocol were given at an interval of 28 days. The survival rates at one, two, and three years were 72.3%, 55.3%, and 40% in the concurrent chemoradiotherapy group, respectively, and 75.3%, 38.5%, and 18.5% in the radiotheray group (P = 0.007), respectively. The survival rates of the patients in the concurrent chemoradiotherapy group who completed one to two cycles and three to four cycles at one, two, and three years were 70%, 53.3%, and 30%, and 74.2%, 57.1%, 48.6% (P = 0.128), respectively. Three-year distant metastasis rates were 10.7% in the concurrent chemoradiotherapy group and 16.9% in the radiotherapy group. Acute toxicity in the concurrent chemoradiotherapy group was higher than in the radiotherapy group. Late toxic side effects were similar in the two groups. Compared with radiotherapy alone, concurrent chemoradiotherapy in the treatment of esophageal carcinoma with local lymph node enlargement can improve the three-year survival rate. Moreover, completion of three to four cycles of chemotherapy may have better efficacy than one to two cycles.

  3. Comparing Item Performance on Three- Versus Four-Option Multiple Choice Questions in a Veterinary Toxicology Course.

    PubMed

    Royal, Kenneth; Dorman, David

    2018-06-09

    The number of answer options is an important element of multiple-choice questions (MCQs). Many MCQs contain four or more options despite the limited literature suggesting that there is little to no benefit beyond three options. The purpose of this study was to evaluate item performance on 3-option versus 4-option MCQs used in a core curriculum course in veterinary toxicology at a large veterinary medical school in the United States. A quasi-experimental, crossover design was used in which students in each class were randomly assigned to take one of two versions (A or B) of two major exams. Both the 3-option and 4-option MCQs resulted in similar psychometric properties. The findings of our study support earlier research in other medical disciplines and settings that likewise concluded there was no significant change in the psychometric properties of three option MCQs when compared to the traditional MCQs with four or more options.

  4. Phytochemical analysis and biological evaluation of selected African propolis samples from Cameroon and Congo.

    PubMed

    Papachroni, Danai; Graikou, Konstantia; Kosalec, Ivan; Damianakos, Harilaos; Ingram, Verina; Chinou, Ioanna

    2015-01-01

    The objective of this study was the chemical analysis of four selected samples of African propolis (Congo and Cameroon) and their biological evaluation. Twenty-one secondary metabolites belonging to four different chemical groups were isolated from the 70% ethanolic extracts of propolis and their structures were elucidated on the basis of spectral evidence. Three triterpenes and two diprenyl-flavonoids were identified from Congo propolis, which has been investigated for the first time, while thirteen triterpenes, three diprenyl-flavonoids, two monoterpenic alcohols and one fatty acid ester have been identified from Cameroon propolis samples. To our knowledge, the identified diprenyl-flavonoids, as well as five of the isolated and determined triterpenes, are reported for the first time in propolis. Moreover, the total polyphenol content was estimated in all extracts and the antimicrobial activities of all four extracts were studied against six Gram-positive and -negative bacteria and three pathogenic fungi, showing an interesting antibacterial profile.

  5. Kinematic synthesis of bevel-gear-type robotic wrist mechanisms

    NASA Astrophysics Data System (ADS)

    Lin, Chen-Chou

    Bevel-gear-type robotic wrist mechanisms are commonly used in industry. The reasons for their popularity are that they are compact, light-weight, and relatively inexpensive. However, there are singularities in their workspace, which substantially degrade their manipulative performance. The objective of this research is to develop an atlas of three-degree-of-freedom bevel-gear-type wrist mechanisms, and through dimensional synthesis to improve their kinematic performance. The dissertation contains two major parts: the first is structural analysis and synthesis, the other is kinematic analysis and dimensional synthesis. To synthesize the kinematic structures of bevel-gear-type wrist mechanisms, the kinematic structures are separated from their functional considerations. All kinematic structures which satisfy the mobility condition are enumerated in an unbiased, systematic manner. Then the bevel-gear-type wrist mechanisms are identified by applying the functional requirements. Structural analysis shows that a three-degree-of-freedom wrist mechanism usually consists of non-fractionated, two degree-of-freedom epicyclic gear train jointed with the base link. Therefore, the structural synthesis can be simplified into a problem of examining the atlas of non-fractionated, two-degree-of-freedom epicyclic gear trains. The resulting bevel-gear-type wrist mechanism has been categorized and evaluated. It is shown that three-degree-of-freedom, four-jointed wrist mechanisms are promising for further improving the kinematic performance. It is found that a spherical planetary gear train is necessarily imbedded in a three-degree-of-freedom, four-jointed wrist mechanism. Therefore, to study the workspace and singularity problems of three-degree-of-freedom four-jointed spherical wrist mechanisms, we have to study the trajectories of spherical planetary gear trains. The parametric equations of the trajectories and some useful geometric properties for the analysis and synthesis of workplace are derived. The workspace boundary equations can be derived via both geometric consideration and Jacobian analysis. The workspace is divided by inner and outer boundaries into regions of accessibility of zero, two, and four. The design criteria of full workspace and a maximum four-root region are established.

  6. Procedure-related haemorrhage in embolisation of intracranial aneurysms with Guglielmi detachable coils.

    PubMed

    Kwon, B J; Han, M H; Oh, C W; Kim, K H; Chang, K H

    2003-08-01

    We reviewed the haemorrhagic complications of the endovascular treatment of intracranial aneurysms, in terms of frequency, pre-embolisation clinical status, clinical and radiological manifestations, management and prognosis. In 275 patients treated for 303 aneurysms over 7 years we had seven (one man and six women--2.3%) with haemorrhage during or immediately after endovascular treatment. All procedures were performed with a standardised protocol of heparinisation and anaesthesia. Four had ruptured aneurysms, two at the tip of the basilar artery, and one ach on the internal carotid and posterior cerebral artery, treated after 12, 5, 14, and 2 days, respectively, three were in Hunt and Hess grade 2 and one in grade 1. Bleeding occurred during coiling in three, after placement of at least four coils, and during manipulation of the guidewire to enter the aneurysm in the fourth. Haemorrhage was manifest as extravasation of contrast medium, with a sudden rise in systolic blood pressure in three patients. The other three patients had unruptured aneurysms; they had stable blood pressure and angiographic findings during the procedure, but one, under sedation, had seizures immediately after insertion of four coils, and the other two had seizures, headache and vomiting on the day following the procedure. Heparin reversal with protamine sulphate was started promptly started when bleeding was detected in four patients, and the embolisation was completed with additional coils in three. Emergency ventricular drainage was performed in the two patients with ruptured aneurysm and one with an unruptured aneurysm who had abnormal neurological responses or hydrocephalus. The bleeding caused a third nerve palsy in one patient, which might have been due to ischaemia and progressively improved.

  7. Isolation of Three Triterpene Saponins, Including Two New Oleanane Derivatives, from Soldanella alpina and Hydrophilic Interaction Liquid Chromatography-Evaporative Light Scattering Detection of these Three Saponins in Four Soldenella Species.

    PubMed

    Haller, Julia; Schwaiger, Stefan; Stuppner, Hermann; Gafner, Frank; Ganzera, Markus

    2017-11-01

    The genus Soldanella is one of the few endemic to Europe. Some of its species have relevance in local traditional medicine. Earlier work has indicated the possible presence of saponins in S. alpina. To investigate S. alpina and other related species for the occurrence of saponins. Following sequential extraction with n-hexane, dichloromethane and ethyl acetate the subsequent methanolic extract of S. alpina roots was fractionated after solvent precipitation using fast centrifugal partition chromatography and column chromatography. Structures were elucidated by LC-MS n , high-resolution MS, hydrolysis experiments and one-dimensional (1D)- and two-dimensional (2D)-NMR. A hydrophilic interaction liquid chromatography method was developed to quantitate saponins in the leaves and roots of four Soldanella species. Three triterpene saponins, two of them new natural products, were isolated from S. alpina. Based on an epoxyoleanal aglycone substituted with four sugar units, they were analytically quantitated using a Kinetex 2.6 μm hydrophilic interaction liquid chromatography (HILIC) column together with a mobile phase comprising of ammonium acetate, water and acetonitrile. Method validation confirmed that the assay meets all requirements in respect to linearity, accuracy, sensitivity and precision. All four Soldanella species investigated contained the three saponins. The lowest total level of the three saponins (1.09%) was observed in S. montana leaves while the highest saponin content (5.14%) was determined in S. alpina roots. The detection of saponins within the genus Soldanella is an indication that further phytochemical examination of this genus may reveal more secondary metabolites of interest. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  8. Target recognition of ladar range images using slice image: comparison of four improved algorithms

    NASA Astrophysics Data System (ADS)

    Xia, Wenze; Han, Shaokun; Cao, Jingya; Wang, Liang; Zhai, Yu; Cheng, Yang

    2017-07-01

    Compared with traditional 3-D shape data, ladar range images possess properties of strong noise, shape degeneracy, and sparsity, which make feature extraction and representation difficult. The slice image is an effective feature descriptor to resolve this problem. We propose four improved algorithms on target recognition of ladar range images using slice image. In order to improve resolution invariance of the slice image, mean value detection instead of maximum value detection is applied in these four improved algorithms. In order to improve rotation invariance of the slice image, three new improved feature descriptors-which are feature slice image, slice-Zernike moments, and slice-Fourier moments-are applied to the last three improved algorithms, respectively. Backpropagation neural networks are used as feature classifiers in the last two improved algorithms. The performance of these four improved recognition systems is analyzed comprehensively in the aspects of the three invariances, recognition rate, and execution time. The final experiment results show that the improvements for these four algorithms reach the desired effect, the three invariances of feature descriptors are not directly related to the final recognition performance of recognition systems, and these four improved recognition systems have different performances under different conditions.

  9. A Qualitative Study of Tribal Colleges and Universities that Have Transitioned: From Two-Year Associate Degree Granting Institutions to Targeted Four-Year Bachelor Degree Granting Institutions

    ERIC Educational Resources Information Center

    Chandler, Lynette

    2010-01-01

    The purpose of this qualitative case study was to analyze how tribal colleges and Universities have transitioned from two-year associate degree granting institutions to offering four-year bachelor degree granting institutions. This case study includes three tribal colleges: Sitting Bull College, Salish Kootenai College and Turtle Mountain…

  10. Comparison of norfloxacin versus nalidixic acid in therapy of acute urinary tract infections

    PubMed Central

    Selin, Liisa K; Harding, Godfrey KM; Thomson, Margaret J; Kennedy, James K; Urias, Barbara A; Ronald, Allan R

    1990-01-01

    Thirty-seven adult patients with acute urinary tract infections (UTI) were randomized to receive either a seven day (lower UTI) or a 14 day (upper UTI) course of norfloxacin 400 mg orally twice daily, or nalidixic acid 1 g orally four times per day. Mean age, underlying disease and infecting organisms were similar in the two groups. Nine patients in the norfloxacin group and seven in the nalidixic acid group had presumptive evidence of upper UTI. Overall, 12 patients had antibody-coated bacteria-positive infections. The infecting organisms were: Escherichia coli (27), coagulase-negative staphylococci (four), Citrobacter freundii (three), Klebsiella pneumoniae (three), and Proteus mirabilis, Proteus vulgaris, Pseudomonas aeruginosa, Enterobacter agglomerans, Streptococcus agalactiae, Enterococcus faecalis (one of each). All of the organisms were susceptible to norfloxacin, while 81% were susceptible to nalidixic acid. The effects on the periurethral and anal canal flora were similar in both groups. Five patients in each group experienced adverse clinical effects. The cure rates for norfloxacin and nalidixic acid were 79 and 83%, respectively. There were two failures, two relapses and four reinfections in the norfloxacin group. In the nalidixic acid group, there were two failures, one relapse and four reinfections. One of the failure patients in the nalidixic acid group developed resistance to the drug, and two of the four reinfections were due to organisms resistant to nalidixic acid. In this patient population it was concluded that nalidixic acid may be as effective as norfloxacin in the treatment of acute, symptomatic UTI. PMID:22553437

  11. Outcomes Evaluation of Zero-Profile Devices Compared to Stand-Alone PEEK Cages for the Treatment of Three- and Four-Level Cervical Disc Disease.

    PubMed

    Gerszten, Peter C; Paschel, Erin; Mashaly, Hazem; Sabry, Hatem; Jalalod'din, Hasan; Saoud, Khaled

    2016-09-10

    Anterior cervical discectomy and fusion (ACDF) is a well-accepted treatment option for patients with cervical spine disease. Three- and four-level discectomies are known to be associated with a higher complication rate and lower fusion rate than single-level surgery. This study was performed to evaluate and compare zero-profile fixation and stand-alone PEEK cages for three- and four-level ACDF. Two cohorts of patients who underwent ACDF for the treatment of three- and four-level disease were compared. Thirty-three patients underwent implantation of zero-profile devices that included titanium screw fixation (Group A). Thirty-five patients underwent implantation of stand-alone PEEK cages without any form of screw fixation (Group B). In Group A, twenty-seven patients underwent a three-level and six patients a four-level ACDF, with a total of 105 levels. In Group B, thirty patients underwent a three-level and five patients underwent a four-level ACDF, with a total number of 110 levels. In Group A, the mean preoperative visual analog scale score (VAS) for arm pain was 6.4 (range 3-8), and the mean postoperative VAS for arm pain decreased to 2.5 (range 1-7). In group B, the mean preoperative VAS of arm pain was 7.1 (range 3-10), and the mean postoperative VAS of arm pain decreased to 2 (range 0-4). In Group A, four patients (12%) developed dysphagia, and in Group B, three patients (9%) developed dysphagia.  Conclusions: This study found zero-profile instrumentation and PEEK cages to be both safe and effective for patients who underwent three- and four-level ACDF, comparable to reported series using plate devices. Rates of dysphagia for the cohort were much lower than reports using plate devices. Zero-profile segmental fixation devices and PEEK cages may be considered as viable alternatives over plate fixation for patients requiring multi-level anterior cervical fusion surgery.

  12. 40 CFR 80.101 - Standards applicable to refiners and importers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... are produced or imported over a period no longer than one month; (iii) Uses the total of the volumes... Administrator may grant an averaging period of two, three, four or five years upon petition of a refiner who: (A... for a two or three year averaging period must be submitted by June 1, 2003. Regardless of the...

  13. 40 CFR 80.101 - Standards applicable to refiners and importers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... are produced or imported over a period no longer than one month; (iii) Uses the total of the volumes... Administrator may grant an averaging period of two, three, four or five years upon petition of a refiner who: (A... for a two or three year averaging period must be submitted by June 1, 2003. Regardless of the...

  14. 40 CFR 80.101 - Standards applicable to refiners and importers.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... are produced or imported over a period no longer than one month; (iii) Uses the total of the volumes... Administrator may grant an averaging period of two, three, four or five years upon petition of a refiner who: (A... for a two or three year averaging period must be submitted by June 1, 2003. Regardless of the...

  15. A Comparison of IRT Proficiency Estimation Methods under Adaptive Multistage Testing

    ERIC Educational Resources Information Center

    Kim, Sooyeon; Moses, Tim; Yoo, Hanwook

    2015-01-01

    This inquiry is an investigation of item response theory (IRT) proficiency estimators' accuracy under multistage testing (MST). We chose a two-stage MST design that includes four modules (one at Stage 1, three at Stage 2) and three difficulty paths (low, middle, high). We assembled various two-stage MST panels (i.e., forms) by manipulating two…

  16. Stiffness and shrinkage of green and dry joists

    Treesearch

    Lyman W. Wood; Lawrence A. Soltis

    1964-01-01

    This report gives information on the edgewise modulus of elasticity, stiffness, and shrinkage of 360 joists in three species, three grades, and two sizes, each species obtained from two sources. Each joist was evaluated nondestructively at four moisture content values ranging from the green condition to about 11 percent. Information is also given on specific gravity,...

  17. Investigation of Lyapunov stability of a central configuration in the restricted four-body problem

    NASA Astrophysics Data System (ADS)

    Bardin, B. S.; Esipov, P. A.

    2018-05-01

    The restricted planar four-body problem is considered. It is supposed that one of four bodies has infinitesimal mass and does not affect on motions of three other bodies. If two bodies have equal masses then there exists a central configuration such that three bodies are located in vertex of an equilateral triangle and the fourth body having infinitesimal mass is located in perpendicular bisector of the triangle. By using the method of normal forms and KAM theory stability of the above configuration is studied in the sense of Lyapunov.

  18. Poikiloderma with Neutropenia in Morocco: a Report of Four Cases.

    PubMed

    Aglaguel, Ayoub; Abdelghaffar, Houria; Ailal, Fatima; Habti, Norddine; Hesse, Sebastian; Kohistani, Naschla; Klein, Christoph; Bousfiha, Ahmed Aziz

    2017-05-01

    Poikiloderma with Neutropenia (PN) is inherited genodermatosis which results from a biallelic mutation in the USB1 gene (U Six Biogenesis 1). PN, first described in Navajo Native Americans, is characterized by early onset poikiloderma, pachyonychia, palmo-plantar hyperkeratosis, and permanent neutropenia. This condition results in frequent respiratory tract infections during infancy and childhood. From 2011 to 2013, four cases of PN were diagnosed in Morocco. In this paper, we report the first four cases of PN diagnosed in Morocco, out of three unrelated consanguinous families. We investigated the genetic, immunological, and clinical features of four Moroccan patients with PN from three unrelated consanguinous families. Mean age at onset was 3 months and mean age at diagnosis was 7.5 years. The diagnosis of these PN patients was made based on clinical features and confirmed by molecular analysis for three cases. We identified two undescribed homozygous mutations in the USB1 gene: c.609 + 1G>A in two siblings and c.518 T>G(p.(Leu173Arg)) in the other case. This report confirms the clinical and genetic identity of Poikiloderma with Neutropenia syndrome.

  19. Multivariate analysis of chromatographic retention data as a supplementary means for grouping structurally related compounds.

    PubMed

    Fasoula, S; Zisi, Ch; Sampsonidis, I; Virgiliou, Ch; Theodoridis, G; Gika, H; Nikitas, P; Pappa-Louisi, A

    2015-03-27

    In the present study a series of 45 metabolite standards belonging to four chemically similar metabolite classes (sugars, amino acids, nucleosides and nucleobases, and amines) was subjected to LC analysis on three HILIC columns under 21 different gradient conditions with the aim to explore whether the retention properties of these analytes are determined from the chemical group they belong. Two multivariate techniques, principal component analysis (PCA) and discriminant analysis (DA), were used for statistical evaluation of the chromatographic data and extraction similarities between chemically related compounds. The total variance explained by the first two principal components of PCA was found to be about 98%, whereas both statistical analyses indicated that all analytes are successfully grouped in four clusters of chemical structure based on the retention obtained in four or at least three chromatographic runs, which, however should be performed on two different HILIC columns. Moreover, leave-one-out cross-validation of the above retention data set showed that the chemical group in which an analyte belongs can be 95.6% correctly predicted when the analyte is subjected to LC analysis under the same four or three experimental conditions as the all set of analytes was run beforehand. That, in turn, may assist with disambiguation of analyte identification in complex biological extracts. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Inclusive three- and four-jet production in multi-Regge kinematics at the LHC

    NASA Astrophysics Data System (ADS)

    Caporale, Francesco; Celiberto, Francesco G.; Chachamis, Grigorios; Gómez, D. Gordo; Vera, Agustín Sabio

    2017-03-01

    A study of differential cross sections for the production of three and four jets in multi-Regge kinematics is presented. The main focus lies on the azimuthal angle dependences in events with two forward/backward jets tagged in the final state. Furthermore, the tagging of one or two extra jets in more central regions of the detector with a relative separation in rapidity from each other is requested. It is found that the dependence of the cross sections on the transverse momenta and the rapidities of the central jet(s) can offer new means of studying the onset of BFKL dynamics.

  1. Reformulations of Yang–Mills theories with space–time tensor fields

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Guo, Zhi-Qiang, E-mail: gzhqedu@gmail.com

    2016-01-15

    We provide the reformulations of Yang–Mills theories in terms of gauge invariant metric-like variables in three and four dimensions. The reformulations are used to analyze the dimension two gluon condensate and give gauge invariant descriptions of gluon polarization. In three dimensions, we obtain a non-zero dimension two gluon condensate by one loop computation, whose value is similar to the square of photon mass in the Schwinger model. In four dimensions, we obtain a Lagrangian with the dual property, which shares the similar but different property with the dual superconductor scenario. We also make discussions on the effectiveness of one loopmore » approximation.« less

  2. Upper Airway Injury in Dogs Secondary to Trauma: 10 Dogs (2000-2011).

    PubMed

    Basdani, Eleni; Papazoglou, Lysimachos G; Patsikas, Michail N; Kazakos, Georgios M; Adamama-Moraitou, Katerina K; Tsokataridis, Ioannis

    2016-01-01

    Ten dogs that presented with trauma-induced upper airway rupture or stenosis were reviewed. Tracheal rupture was seen in seven dogs, tracheal stenosis in one dog, and laryngeal rupture in two dogs. Clinical abnormalities included respiratory distress in five dogs, subcutaneous emphysema in eight, air leakage through the cervical wound in seven, stridor in three dogs, pneumomediastinum in four and pneumothorax in one dog. Reconstruction with simple interrupted sutures was performed in four dogs, tracheal resection and end-to-end anastomosis in five dogs, and one dog was euthanized intraoperatively. Complications were seen in three dogs including aspiration pneumonia in one and vocalization alterations in two dogs.

  3. Efficacy and tolerability of a new topical nitric-zinc preparation for "difficult-to-treat" warts.

    PubMed

    Janniger, Camila K; Schwartz, Robert A

    2017-03-01

    Treating plantar, periungual, and external genital warts can be challenging. A prospective study from four centers in Italy evaluated 37 immunocompetent patients with single or multiple warts and treated each lesion with a nitric-zinc topical solution composed of organic and inorganic acids meant to devitalize tissue and destroy HPV DNA in infected keratinocytes. Thirty of the 37 patients had external genital warts, two had plantar warts, two had palm and finger warts, and three had subungual warts for a total of 55 lesions treated. Nitric-zinc aqueous solution was applied over each wart utilizing a 30 µL capillary tube until a whitening response was observed. Additional applications as needed were accomplished at 2-week intervals until the wart was gone. In those with hand, plantar, and subungual warts, there was a 100% clearance after two to three sessions. Three with external genital warts had only a partial response and one no benefit after four applications. Thus, this approach was effective in external genital and other "difficult-to-treat" warts in 90% of patients after one to four applications. It also was easy to use with no adverse events noted. © 2016 Wiley Periodicals, Inc.

  4. Apparent predation by cattle at grassland bird nests

    USGS Publications Warehouse

    Nack, Jamie L.; Ribic, C.A.

    2005-01-01

    We document the first cases of cattle behaving as avian predators, removing nestlings and eggs from three active ground nests in continuously grazed pastures in southwestern Wisconsin, 2000-2001. Cows removed three of four Savannah Sparrow (Passerculus sandwichensis) eggs from one nest (the fourth egg was damaged), all four Eastern Meadowlark (Sturnella magna) nestlings from another, and all three Savannah Sparrow nestlings from a third. We found only two of three missing eggs (intact) and one of seven missing nestlings (dead) near two of the nests. Cows may have eaten the egg and nestlings we were unable to account for; alternatively, the egg and nestlings may have been scavenged by predators or removed from the area by the adult birds. Without videotape documentation, we would have attributed nest failure to traditional predators and cattle would not have been implicated. We may be underestimating the impact of cattle on ground nests by not considering cattle as potential predators.

  5. Factor structure of overall autobiographical memory usage: the directive, self and social functions revisited.

    PubMed

    Rasmussen, Anne S; Habermas, Tilmann

    2011-08-01

    According to theory, autobiographical memory serves three broad functions of overall usage: directive, self, and social. However, there is evidence to suggest that the tripartite model may be better conceptualised in terms of a four-factor model with two social functions. In the present study we examined the two models in Danish and German samples, using the Thinking About Life Experiences Questionnaire (TALE; Bluck, Alea, Habermas, & Rubin, 2005), which measures the overall usage of the three functions generalised across concrete memories. Confirmatory factor analysis supported the four-factor model and rejected the theoretical three-factor model in both samples. The results are discussed in relation to cultural differences in overall autobiographical memory usage as well as sharing versus non-sharing aspects of social remembering.

  6. Heterobimetallic thiocyanato-bridged coordination polymers based on [Hg(SCN) 4] 2-: Synthesis, crystal structure, magnetic properties and ESR studies

    NASA Astrophysics Data System (ADS)

    Jian, Fang-Fang; Xiao, Hai-Lian; Liu, Fa Qian

    2006-12-01

    Three new M/Hg bimetallic thiocyanato-bridged coordination polymers; [Hg(SCN) 4Ni(Im) 3] ∞1, [Hg(SCN) 4Mn(Im) 2] ∞2, and [Hg(SCN) 4Cu(Me-Im) 2 Hg(SCN) 4Cu(Me-Im) 4] ∞3, (Im=imidazole, Me-Im= N-methyl-imidazole), have been synthesized and characterized by means of elemental analysis, ESR, and single-crystal X-ray. X-ray diffraction analysis reveals that these three complexes all form 3D network structure, and their structures all contain a thiocyanato-bridged Hg⋯M⋯Hg chain ( M=Mn, Ni, Cu) in which the metal and mercury centers exhibit different coordination environments. In complex 1, the [Hg(SCN) 4] 2- anion connects three [Ni(Im) 3] 2+ using three SCN ligands giving rise to a 3D structure, and in complex 2, four SCN ligands bridge [Hg(SCN) 4] 2- and [Mn(Im) 2] 2+ to form a 3D structure. The structure of 3 contains two copper atoms with distinct coordination environment; one is coordinated by four N-methyl-imidazole ligands and two axially elongated SCN groups, and another by four SCN groups (two elongated) and two N-methyl-imidazole ligands. The magnetic property of complex 1 has been investigated. The spin state structure in hetermetallic NiHgNi systems of complex 1 is irregular. The ESR spectra results of complex 3 demonstrate Cu 2+ ion lie on octahedral environment.

  7. Chemotherapy for neuroendocrine tumors: the Beatson Oncology Centre experience.

    PubMed

    Hatton, M Q; Reed, N S

    1997-01-01

    The role of chemotherapy in malignant neuroendocrine tumours is difficult to assess because of their rarity and variation in biological behaviour. We present a retrospective review of chemotherapy given to 18 patients with metastatic and one with locally advanced neuroendocrine tumours. There were eight poorly differentiated neuroendocrine tumours, six thyroid medullary carcinomas, two phaeochromocytomas, two pancreatic islet cell tumours and one undifferentiated neuroblastoma. Four patients were given 3-weekly dacarbazine, vincristine and cyclophosphamide (DOC) chemotherapy. In eight patients, this regimen was modified by substituting the dacarbazine and cisplatin and etoposide (OPEC). A further six patients were treated with dacarbazine reintroduced into the 3-weekly regimen (DOPEC). The remaining patient received cisplatin and etoposide. There were two complete responses (both with OPEC) and eight partial responses (two with DOC, three with OPEC and three with DOPEC). Five patients had stable disease and four progressed. Four received further chemotherapy on relapse, producing one complete and one partial response. The median response duration to initial chemotherapy was 10 months (range 3-34). The median survival was 12 months (range 1-42). The main toxicity was haematological, with grade 3-4 neutropenia in 12 patients; eight suffered episodes of sepsis. One death was treatment related. Other toxicity was mild although three patients discontinued vincristine with grade 2 neurotoxicity. The response rate and side effects of these three regimens appear comparable. We conclude that, although these patient numbers are small, combination chemotherapy produces an encouraging response rate (53%; 95% CI 30-75) in malignant neuroendocrine tumours, with acceptable toxicity.

  8. Quantum Tasks with Non-maximally Quantum Channels via Positive Operator-Valued Measurement

    NASA Astrophysics Data System (ADS)

    Peng, Jia-Yin; Luo, Ming-Xing; Mo, Zhi-Wen

    2013-01-01

    By using a proper positive operator-valued measure (POVM), we present two new schemes for probabilistic transmission with non-maximally four-particle cluster states. In the first scheme, we demonstrate that two non-maximally four-particle cluster states can be used to realize probabilistically sharing an unknown three-particle GHZ-type state within either distant agent's place. In the second protocol, we demonstrate that a non-maximally four-particle cluster state can be used to teleport an arbitrary unknown multi-particle state in a probabilistic manner with appropriate unitary operations and POVM. Moreover the total success probability of these two schemes are also worked out.

  9. Comparison in the quality of distractors in three and four options type of multiple choice questions

    PubMed Central

    Rahma, Nourelhouda A A; Shamad, Mahdi M A; Idris, Muawia E A; Elfaki, Omer Abdelgadir; Elfakey, Walyedldin E M; Salih, Karimeldin M A

    2017-01-01

    Introduction The number of distractors needed for high quality multiple choice questions (MCQs) will be determined by many factors. These include firstly whether English language is their mother tongue or a foreign language; secondly whether the instructors who construct the questions are experts or not; thirdly the time spent on constructing the options is also an important factor. It has been observed by Tarrant et al that more time is often spent on constructing questions than on tailoring sound, reliable, and valid distractors. Objectives Firstly, to investigate the effects of reducing the number of options on psychometric properties of the item. Secondly, to determine the frequency of functioning distractors among three or four options in the MCQs examination of the dermatology course in University of Bahri, College of Medicine. Materials and methods This is an experimental study which was performed by means of a dermatology exam, MCQs type. Forty MCQs, with one correct answer for each question were constructed. Two sets of this exam paper were prepared: in the first one, four options were given, including one key answer and three distractors. In the second set, one of the three distractors was deleted randomly, and the sequence of the questions was kept in the same order. Any distracter chosen by less than 5% of the students was regarded as non-functioning. Kuder-Richardson Formula 20 (Kr-20) measures the internal consistency and reliability of an examination with an acceptable range 0.8–1.0. Chi square test was used to compare the distractors in the two exams. Results A significant difference was observed in discrimination and difficulty indexes for both sets of MCQs. More distractors were non-functional for set one (of four options), but slightly more reliable. The reliability (Kr-20) was slightly higher for set one (of four options). The average marks in option three and four were 34.163 and 33.140, respectively. Conclusion Compared to set 1 (four options), set 2 (of three options) was more discriminating and associated with low difficulty index but its reliability was low. PMID:28442942

  10. Comparison in the quality of distractors in three and four options type of multiple choice questions.

    PubMed

    Rahma, Nourelhouda A A; Shamad, Mahdi M A; Idris, Muawia E A; Elfaki, Omer Abdelgadir; Elfakey, Walyedldin E M; Salih, Karimeldin M A

    2017-01-01

    The number of distractors needed for high quality multiple choice questions (MCQs) will be determined by many factors. These include firstly whether English language is their mother tongue or a foreign language; secondly whether the instructors who construct the questions are experts or not; thirdly the time spent on constructing the options is also an important factor. It has been observed by Tarrant et al that more time is often spent on constructing questions than on tailoring sound, reliable, and valid distractors. Firstly, to investigate the effects of reducing the number of options on psychometric properties of the item. Secondly, to determine the frequency of functioning distractors among three or four options in the MCQs examination of the dermatology course in University of Bahri, College of Medicine. This is an experimental study which was performed by means of a dermatology exam, MCQs type. Forty MCQs, with one correct answer for each question were constructed. Two sets of this exam paper were prepared: in the first one, four options were given, including one key answer and three distractors. In the second set, one of the three distractors was deleted randomly, and the sequence of the questions was kept in the same order. Any distracter chosen by less than 5% of the students was regarded as non-functioning. Kuder-Richardson Formula 20 (Kr-20) measures the internal consistency and reliability of an examination with an acceptable range 0.8-1.0. Chi square test was used to compare the distractors in the two exams. A significant difference was observed in discrimination and difficulty indexes for both sets of MCQs. More distractors were non-functional for set one (of four options), but slightly more reliable. The reliability (Kr-20) was slightly higher for set one (of four options). The average marks in option three and four were 34.163 and 33.140, respectively. Compared to set 1 (four options), set 2 (of three options) was more discriminating and associated with low difficulty index but its reliability was low.

  11. Clifford Algebra Implying Three Fermion Generations Revisited

    NASA Astrophysics Data System (ADS)

    Krolikowski, Wojciech

    2002-09-01

    The author's idea of algebraic compositeness of fundamental particles, allowing to understand the existence in Nature of three fermion generations, is revisited. It is based on two postulates. Primo, for all fundamental particles of matter the Dirac square-root procedure √ {p2} → {Γ }(N)p works, leading to a sequence N = 1,2,3, ... of Dirac-type equations, where four Dirac-type matrices {Γ }(N)μ are embedded into a Clifford algebra via a Jacobi definition introducing four ``centre-of-mass'' and (N-1)× four ``relative'' Dirac-type matrices. These define one ``centre-of-mass'' and (N-1) ``relative'' Dirac bispinor indices. Secundo, the ``centre-of-mass'' Dirac bispinor index is coupled to the Standard Model gauge fields, while (N-1) ``relative'' Dirac bispinor indices are all free indistinguishable physical objects obeying Fermi statistics along with the Pauli principle which requires the full antisymmetry with respect to ``relative'' Dirac indices. This allows only for three Dirac-type equations with N = 1,3,5 in the case of N odd, and two with N = 2,4 in the case of N even. The first of these results implies unavoidably the existence of three and only three generations of fundamental fermions, namely leptons and quarks, as labelled by the Standard Model signature. At the end, a comment is added on the possible shape of Dirac 3x3 mass matrices for four sorts of spin-1/2 fundamental fermions appearing in three generations. For charged leptons a prediction is mτ = 1776.80 MeV, when the input of experimental me and mμ is used.

  12. Antimicrobial-resistant bacterial populations and antimicrobial resistance genes obtained from environments impacted by livestock and municipal waste

    USDA-ARS?s Scientific Manuscript database

    This study compared the populations of antimicrobial-resistant bacteria and the repertoire of antimicrobial resistance genes in four environments: effluent of three municipal waste water treatment facilities, three cattle feedlot runoff catchment ponds, three swine waste lagoons, and two "low impact...

  13. Lasting effects of short-term training on preschoolers' street-crossing behavior.

    PubMed

    Albert, Rachel R; Dolgin, Kim G

    2010-03-01

    Can short-term training improve preschoolers' knowledge of road-crossing concepts as well as behavior in a real traffic situation? Forty children, aged four to five years, were assigned to one of four conditions (game, story, song, and control). Each condition participated in four 15-min classroom-based lessons over four weeks. Two assessments measuring knowledge of street-crossing concepts and one assessment measuring behavior on a real street were used to evaluate performance at baseline and one week and six months post-training. Children in all three experimental conditions showed a significant improvement over the control on the two conceptual assessments. Only children in the game condition significantly improved their behavior on the street-crossing assessment. Furthermore, children in all three experimental conditions retained the same levels of improvement at the six-month follow-up. These results demonstrate that one hour of training can create lasting improvements on preschool children's conceptual knowledge of traffic safety and road-crossing behavior on a real street. Copyright 2009 Elsevier Ltd. All rights reserved.

  14. Four-phase or two-phase signal plan? A study on four-leg intersection by cellular automaton simulations

    NASA Astrophysics Data System (ADS)

    Jin, Cheng-Jie; Wang, Wei; Jiang, Rui

    2016-08-01

    The proper setting of traffic signals at signalized intersections is one of the most important tasks in traffic control and management. This paper has evaluated the four-phase traffic signal plans at a four-leg intersection via cellular automaton simulations. Each leg consists of three lanes, an exclusive left-turn lane, a through lane, and a through/right-turn lane. For a comparison, we also evaluate the two-phase signal plan. The diagram of the intersection states in the space of inflow rate versus turning ratio has been presented, which exhibits four regions: In region I/II/III, congestion will propagate upstream and laterally and result in queue spillover with both signal plans/two-phase signal plan/four-phase signal plan, respectively. Therefore, neither signal plan works in region I, and only the four-phase signal plan/two-phase signal plan works in region II/III. In region IV, both signal plans work, but two-phase signal plan performs better in terms of average delays of vehicles. Finally, we study the diagram of the intersection states and average delays in the asymmetrical configurations.

  15. Efficient schemes for deterministic joint remote preparation of an arbitrary four-qubit W-type entangled state

    NASA Astrophysics Data System (ADS)

    Fu, Hao; Ma, Peng-Cheng; Chen, Gui-Bin; Li, Xiao-Wei; Zhan, You-Bang

    2017-06-01

    We present three schemes for the joint remote state preparation (JRSP) of an arbitrary four-qubit W-type entangled state with complex coefficients via four and two three-qubit GHZ states as the quantum channel. In these schemes, two senders (or N senders) share the original state which they wish to help the receiver to remotely prepare. To complete the JRSP schemes, some novel sets of mutually orthogonal basis vectors are introduced. It is shown that, only if two senders (or N senders) collaborate with each other, and perform projective measurements under suitable measuring basis on their own qubits, the receiver can reconstruct the original state by means of some appropriate unitary operations. It is shown that, in all our schemes, the total success probability of the JRSP can reach 1. Specially, compared with the first scheme in our paper, the entanglement resource in the second scheme can be reduced. This means that the scheme is more efficient and economical.

  16. Three-dimensional volume containing multiple two-dimensional information patterns

    NASA Astrophysics Data System (ADS)

    Nakayama, Hirotaka; Shiraki, Atsushi; Hirayama, Ryuji; Masuda, Nobuyuki; Shimobaba, Tomoyoshi; Ito, Tomoyoshi

    2013-06-01

    We have developed an algorithm for recording multiple gradated two-dimensional projection patterns in a single three-dimensional object. When a single pattern is observed, information from the other patterns can be treated as background noise. The proposed algorithm has two important features: the number of patterns that can be recorded is theoretically infinite and no meaningful information can be seen outside of the projection directions. We confirmed the effectiveness of the proposed algorithm by performing numerical simulations of two laser crystals: an octagonal prism that contained four patterns in four projection directions and a dodecahedron that contained six patterns in six directions. We also fabricated and demonstrated an actual prototype laser crystal from a glass cube engraved by a laser beam. This algorithm has applications in various fields, including media art, digital signage, and encryption technology.

  17. Joint Remote State Preparation Schemes for Two Different Quantum States Selectively

    NASA Astrophysics Data System (ADS)

    Shi, Jin

    2018-05-01

    The scheme for joint remote state preparation of two different one-qubit states according to requirement is proposed by using one four-dimensional spatial-mode-entangled KLM state as quantum channel. The scheme for joint remote state preparation of two different two-qubit states according to requirement is also proposed by using one four-dimensional spatial-mode-entangled KLM state and one three-dimensional spatial-mode-entangled GHZ state as quantum channels. Quantum non-demolition measurement, Hadamard gate operation, projective measurement and unitary transformation are included in the schemes.

  18. Virtual screening applications: a study of ligand-based methods and different structure representations in four different scenarios.

    PubMed

    Hristozov, Dimitar P; Oprea, Tudor I; Gasteiger, Johann

    2007-01-01

    Four different ligand-based virtual screening scenarios are studied: (1) prioritizing compounds for subsequent high-throughput screening (HTS); (2) selecting a predefined (small) number of potentially active compounds from a large chemical database; (3) assessing the probability that a given structure will exhibit a given activity; (4) selecting the most active structure(s) for a biological assay. Each of the four scenarios is exemplified by performing retrospective ligand-based virtual screening for eight different biological targets using two large databases--MDDR and WOMBAT. A comparison between the chemical spaces covered by these two databases is presented. The performance of two techniques for ligand--based virtual screening--similarity search with subsequent data fusion (SSDF) and novelty detection with Self-Organizing Maps (ndSOM) is investigated. Three different structure representations--2,048-dimensional Daylight fingerprints, topological autocorrelation weighted by atomic physicochemical properties (sigma electronegativity, polarizability, partial charge, and identity) and radial distribution functions weighted by the same atomic physicochemical properties--are compared. Both methods were found applicable in scenario one. The similarity search was found to perform slightly better in scenario two while the SOM novelty detection is preferred in scenario three. No method/descriptor combination achieved significant success in scenario four.

  19. Detection of Atmospheric Carbon Dioxide from a Shuttle-Borne Lidar.

    DTIC Science & Technology

    1982-12-01

    d, e_! *Pnl * cooling of the stratosphere. This will occur due to absorp- tion of the earth’s infrared radiation by CO2, and subse- quent emission of...and four vibrational modes. The available energy bands are a function of three vibrational quantum numbers describing the four vibrational modes: 1...insufficient to describe the energy levels based solely on three vibrational quantum numbers, and the rotational quantum number (J). Two additional .".,. 8

  20. Brant (Branta bernnicla)

    USGS Publications Warehouse

    Ward, David H.; Derksen, Dirk V.; Reed, A.; Sedinger, J.S.

    2013-01-01

    The Brant (called Brent Goose in Europe) is a small dark goose that occurs throughout much of the northern hemisphere. In contrast to other goose species, Brant are characterized by their extensive use of native coastal habitats outside the breeding season. Three to four subspecies are recognized (see Systematics), mainly on the basis of plumage characteristics. The two/three North American subspecies are further separated into four subpopulations based on genetics, location of breeding and wintering areas, and migration routes.

  1. "Developing a Perspective", "Inter-Connecting", and "Bringing It Together": Who Chooses to Use a Labelling Feature in Online Conversations in a Graduate Course?

    ERIC Educational Resources Information Center

    Bures, Eva Mary; Schmid, Richard F.; Abrami, Philip C.

    2009-01-01

    This study explores a labelling feature that allows students to tag parts of their online messages. Data comes from four sequentially offered sessions of a graduate education course. Students engaged in two to three online activities in groups of three or four. Students (n = 53) contributed from 0 to 56 labels (M = 12.42, SD = 13.50) and 18 to 114…

  2. Two Cathelicidin Genes Are Present in both Rainbow Trout (Oncorhynchus mykiss) and Atlantic Salmon (Salmo salar)

    PubMed Central

    Chang, Chin-I; Zhang, Yong-An; Zou, Jun; Nie, Pin; Secombes, Christopher J.

    2006-01-01

    Further to the previous finding of the rainbow trout rtCATH_1 gene, this paper describes three more cathelicidin genes found in salmonids: two in Atlantic salmon, named asCATH_1 and asCATH_2, and one in rainbow trout, named rtCATH_2. All the three new salmonid cathelicidin genes share the common characteristics of mammalian cathelicidin genes, such as consisting of four exons and possessing a highly conserved preproregion and four invariant cysteines clustered in the C-terminal region of the cathelin-like domain. The asCATH_1 gene is homologous to the rainbow trout rtCATH_1 gene, in that it possesses three repeat motifs of TGGGGGTGGC in exon IV and two cysteine residues in the predicted mature peptide, while the asCATH_2 gene and rtCATH_2 gene are homologues of each other, with 96% nucleotide identity. Salmonid cathelicidins possess the same elastase-sensitive residue, threonine, as hagfish cathelicidins and the rabbit CAP18 molecule. The cleavage site of the four salmonid cathelicidins is within a conserved amino acid motif of QKIRTRR, which is at the beginning of the sequence encoded by exon IV. Two 36-residue peptides corresponding to the core part of rtCATH_1 and rtCATH_2 were chemically synthesized and shown to exhibit potent antimicrobial activity. rtCATH_2 was expressed constitutively in gill, head kidney, intestine, skin and spleen, while the expression of rtCATH_1 was inducible in gill, head kidney, and spleen after bacterial challenge. Four cathelicidin genes have now been characterized in salmonids and two were identified in hagfish, confirming that cathelicidin genes evolved early and are likely present in all vertebrates. PMID:16377685

  3. An experimental comparison of conventional two-bank and novel four-bank dynamic MLC tracking.

    PubMed

    Davies, G A; Clowes, P; McQuaid, D; Evans, P M; Webb, S; Poludniowski, G

    2013-03-07

    The AccuLeaf mMLC featuring four multileaf-collimator (MLC) banks has been used for the first time for an experimental comparison of conventional two-bank with novel four-bank dynamic MLC tracking of a two-dimensional sinusoidal respiratory motion. This comparison was performed for a square aperture, and for three conformal treatment apertures from clinical radiotherapy lung cancer patients. The system latency of this prototype tracking system was evaluated and found to be 1.0 s and the frequency at which MLC positions could be updated, 1 Hz, and therefore accurate MLC tracking of irregular patient motion would be difficult with the system in its current form. The MLC leaf velocity required for two-bank-MLC and four-bank-MLC tracking was evaluated for the apertures studied and a substantial decrease was found in the maximum MLC velocity required when four-banks were used for tracking rather than two. A dosimetric comparison of the two techniques was also performed and minimal difference was found between two-bank-MLC and four-bank-MLC tracking. The use of four MLC banks for dynamic MLC tracking is shown to be potentially advantageous for increasing the delivery efficiency compared with two-bank-MLC tracking where difficulties are encountered if large leaf shifts are required to track motion perpendicular to the direction of leaf travel.

  4. Defining a Bobath clinical framework - A modified e-Delphi study.

    PubMed

    Vaughan-Graham, Julie; Cott, Cheryl

    2016-11-01

    To gain consensus within the expert International Bobath Instructors Training Association (IBITA) on a Bobath clinical framework on which future efficacy studies can be based. A three-round modified e-Delphi approach was used with 204 full members of the IBITA. Twenty-one initial statements were generated from the literature. Consensus was defined a priori as at least 80% of the respondents with a level of agreement on a Likert scale of 4 or 5. The Delphi questionnaire for each round was available online for two weeks. Summary reports and subsequent questionnaires were posted within four weeks. Ninety-four IBITA members responded, forming the Delphi panel, of which 68 and 66 responded to Rounds Two and Three, respectively. The 21 initial statements were revised to 17 statements and five new statements in Round Two in which eight statements were accepted and two statements were eliminated. Round Three presented 12 revised statements, all reaching consensus. The Delphi was successful in gaining consensus on a Bobath clinical framework in a geographically diverse expert association, identifying the unique components of Bobath clinical practice. Discussion throughout all three Rounds revolved primarily around the terminology of atypical and compensatory motor behavior and balance.

  5. Catalogue of distribution of lizards (Reptilia: Squamata) from the Brazilian Amazonia. II. Gekkonidae, Phyllodactylidae, Sphaerodactylidae.

    PubMed

    Ribeiro-Júnior, Marco A

    2015-07-02

    I present distribution data of all geckos (Gekkonidae, Phyllodactylidae and Sphaerodactylidae) known from the Brazilian Amazonia, totaling 19 species, belonging to nine genera. This represents six more taxa than previously reported for these families. Data were based on the direct examination of 23,094 specimens deposited in three North American and eight Brazilian museums. Most species (68.4%) are endemic to the Amazonia; non-endemic species are mainly associated with open dry (semideciduous) forest or open vegetation (savanna) enclaves in Amazonia. As a whole, three taxa are widespread in Amazonia, two are restricted to eastern Amazonia, two to western Amazonia, three to northern Amazonia (either widespread or restriced to parts of the Guiana region), one to southern Amazonia, one to southwestern Amazonia, and three to the southern peripheral portion of Amazonia. Additionally, four species have unique distributions and four species have a distribution that is congruent with one of the areas of endemism recognized for other organisms (birds and primates), of which two occur in the area of endemism of Guiana, one in Inambari, and one in Tapajós.

  6. Keratocystic odontogenic tumors related to Gorlin–Goltz syndrome: A clinicopathological study

    PubMed Central

    Khaliq, Mohammed Israr Ul; Shah, Ajaz A.; Ahmad, Irshad; Hasan, Shahid; Jangam, Sagar S.; Farah; Anwar

    2015-01-01

    Background Assess clinicopathological features of patients with keratocystic odontogenic tumor (KCOT) associated with Gorlin–Goltz syndrome in our institution from 2004 to 2015. Method After histopathological analyses of KCOT related to Gorlin–Goltz syndrome, 7 patients were assessed. These patients presented a total of 15 primary and 2 recurrent KCOT. Results All patients presented a multiple KCOT, and 13 lesions were located in mandible (77%) and 4 (23%) in maxilla. Most of the tumors presented a unilocular pattern (71%) and had tooth association (88%). Four patients (57%) were in the age group of 10–19 years and three patients (43%) were in the age group of 20–29 years. There were four male and three female patients. Conclusion KCOT is a frequent manifestation of Gorlin–Goltz syndrome and can be its first sign, mainly in young patients. The four patients presented with two lesions (57%) and three lesions in three patients (43%). PMID:27195205

  7. Keratocystic odontogenic tumors related to Gorlin-Goltz syndrome: A clinicopathological study.

    PubMed

    Khaliq, Mohammed Israr Ul; Shah, Ajaz A; Ahmad, Irshad; Hasan, Shahid; Jangam, Sagar S; Farah; Anwar

    2016-01-01

    Assess clinicopathological features of patients with keratocystic odontogenic tumor (KCOT) associated with Gorlin-Goltz syndrome in our institution from 2004 to 2015. After histopathological analyses of KCOT related to Gorlin-Goltz syndrome, 7 patients were assessed. These patients presented a total of 15 primary and 2 recurrent KCOT. All patients presented a multiple KCOT, and 13 lesions were located in mandible (77%) and 4 (23%) in maxilla. Most of the tumors presented a unilocular pattern (71%) and had tooth association (88%). Four patients (57%) were in the age group of 10-19 years and three patients (43%) were in the age group of 20-29 years. There were four male and three female patients. KCOT is a frequent manifestation of Gorlin-Goltz syndrome and can be its first sign, mainly in young patients. The four patients presented with two lesions (57%) and three lesions in three patients (43%).

  8. Four-Component Catalytic Machinery: Reversible Three-State Control of Organocatalysis by Walking Back and Forth on a Track.

    PubMed

    Mittal, Nikita; Özer, Merve S; Schmittel, Michael

    2018-04-02

    A three-component supramolecular walker system is presented where a two-footed ligand (biped) walks back and forth on a tetrahedral 3D track upon the addition and removal of copper(I) ions, respectively. The addition of N-methylpyrrolidine as a catalyst to the walker system generates a four-component catalytic machinery, which acts as a three-state switchable catalytic ensemble in the presence of substrates for a conjugate addition. The copper(I)-ion-initiated walking process of the biped ligand on the track regulates the catalytic activity in three steps: ON versus int ON (intermediate ON) versus OFF. To establish the operation of the four-component catalytic machinery in a mixture of all constituents, forward and backward cycles were performed in situ illustrating that both the walking process and catalytic action are fully reversible and reproducible.

  9. View Combination: A Generalization Mechanism for Visual Recognition

    ERIC Educational Resources Information Center

    Friedman, Alinda; Waller, David; Thrash, Tyler; Greenauer, Nathan; Hodgson, Eric

    2011-01-01

    We examined whether view combination mechanisms shown to underlie object and scene recognition can integrate visual information across views that have little or no three-dimensional information at either the object or scene level. In three experiments, people learned four "views" of a two dimensional visual array derived from a three-dimensional…

  10. Two Rooms, Two Representations? Episodic-Like Memory in Toddlers and Preschoolers

    ERIC Educational Resources Information Center

    Newcombe, Nora S.; Balcomb, Frances; Ferrara, Katrina; Hansen, Melissa; Koski, Jessica

    2014-01-01

    Episodic memory involves binding together what-where-when associations. In three experiments, we tested the development of memory for such contextual associations in a naturalistic setting. Children searched for toys in two rooms with two different experimenters; each room contained two identical sets of four containers, but arranged differently.…

  11. Moral Judgment in Children: Their Responses to Children's Literature Examined Against Piaget's Stages of Moral Development.

    ERIC Educational Resources Information Center

    Weiger, Myra

    Three stories were presented via audiovisual media to each of three classes in grade two, three classes in grade four, and three in grade six. Children were interviewed individually after the presentations and were asked which misdemeanor in the stories was naughtiest, whether the punishment was fair, what punishment would be fair, and why.…

  12. The science of computing - The evolution of parallel processing

    NASA Technical Reports Server (NTRS)

    Denning, P. J.

    1985-01-01

    The present paper is concerned with the approaches to be employed to overcome the set of limitations in software technology which impedes currently an effective use of parallel hardware technology. The process required to solve the arising problems is found to involve four different stages. At the present time, Stage One is nearly finished, while Stage Two is under way. Tentative explorations are beginning on Stage Three, and Stage Four is more distant. In Stage One, parallelism is introduced into the hardware of a single computer, which consists of one or more processors, a main storage system, a secondary storage system, and various peripheral devices. In Stage Two, parallel execution of cooperating programs on different machines becomes explicit, while in Stage Three, new languages will make parallelism implicit. In Stage Four, there will be very high level user interfaces capable of interacting with scientists at the same level of abstraction as scientists do with each other.

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Seaborg, Glenn T.

    The document represents the 1961 Annual Report of the Atomic Energy Commission (AEC) to Congress. This year's report consists of four parts: Part One, The Atomic Energy Industry for 1961 and Related Activities; Part Two, Nuclear Power Programs for 1961; Part Three, Major Activities in Atomic Energy Programs; and Part Four, Regulatory Activities. Sixteen appendices are also included.

  14. Models for the Representation of Four-Component Systems.

    ERIC Educational Resources Information Center

    Kartzmark, Elinor M.

    1980-01-01

    Describes construction of two inexpensive three-dimensional models (tetrahedrons) using glass tubing and colored plastic sheeting. Diagrams show how these models are used in explaining how a point is plotted in a four-component system and how the composition of a point is deduced from its position in the model. (CS)

  15. Some Effects of Race of Inexperienced Lay Counselors on Black Junior High School Students

    ERIC Educational Resources Information Center

    Heffernon, Andrew; Bruehl, Dieter

    1971-01-01

    Four black and four white college men without prior counseling experience were given eight hours of training in Rogerian counseling and were each assigned two groups, each group composed of three eighth grade black boys. The behavioral measure suggested greater preference for black counselors. (Author)

  16. Environmental Influences on Independent Collaborative Play

    ERIC Educational Resources Information Center

    Mawson, Brent

    2010-01-01

    Data from two qualitative research projects indicated a relationship between the type of early childhood setting and children's independent collaborative play. The first research project involved 22 three and four-year-old children in a daylong setting and 47 children four-year-old children in a sessional kindergarten. The second project involved…

  17. Steady-state analysis of a faulted three-phase four-wire system supplying induction motors with neutrals connected and other single-phase line-to-neutral loads

    NASA Technical Reports Server (NTRS)

    Wood, M. E.

    1980-01-01

    Four wire Wye connected ac power systems exhibit peculiar steady state fault characteristics when the fourth wire of three phase induction motors is connected. The loss of one phase of power source due to a series or shunt fault results in currents higher than anticipated on the remaining two phases. A theoretical approach to compute the fault currents and voltages is developed. A FORTRAN program is included in the appendix.

  18. Evolution of the complications of laparoscopic hysterectomy after a decade: a follow up of the Monash experience.

    PubMed

    Tan, Jason J; Tsaltas, Jim; Hengrasmee, Pattaya; Lawrence, Anthony; Najjar, Haider

    2009-04-01

    A retrospective review of medical records was performed to assess the incidence and types of significant complications encountered during laparoscopic hysterectomy which would affect the use of a laparoscopic approach versus other routes of hysterectomy. A total of 526 consecutive patients' medical data between January 1994 and August 2007 were reviewed. Two hundred and thirty-two laparoscopic-assisted vaginal hysterectomies and 294 total laparoscopic hysterectomies were performed at Monash Medical Centre, a Melbourne tertiary public hospital, and three Melbourne private hospitals, by or under the supervision of three surgeons. Sixteen significant complications occurred. There were two cases of ureteric fistula, two bladder injuries, two bowel obstructions, four postoperative haematomas, one case of a bladder fistula, four conversions to laparotomy and one superficial epigastric artery injury. Inpatient stay ranged from two to six days. Our complication and inpatient stay rates are consistent with the previously reported rates, although there has been a reduction of incidence of visceral injuries with experience and introduction of new equipment.

  19. Treatment of metastatic testicular tumours with bleomycin, etoposide, cisplatin and vincristine (BEPV).

    PubMed Central

    Price, B A; Peters, N H

    1992-01-01

    Between August 1983 and December 1988, 47 patients with metastatic testicular tumours (44 non-seminomatous, three seminomas) were treated with two to six courses of bleomycin, etoposide, cisplatin and vincristine (BEPV). Five stage I tumours were included, three because of raised tumour markers following orchidectomy, one with vascular invasion of spermatic cord vessels and the other with both these features. Forty-four patients (93.6%) are alive and disease free 12-75 months (median 39 months) after completion of BEPV. Further treatment was necessary in 12 of the survivors. Eight had residual disease excised, one of whom received radiotherapy, one additional chemotherapy and one both radiotherapy and chemotherapy. Of the remaining four, two had radiotherapy and two second line chemotherapy. Thirty-one non-seminomatous and the three seminoma patients had small volume disease and all are in complete remission. Ten of the 13 patients with bulky disease are alive. It is concluded that BEPV is a well-tolerated, effective, first line therapy for patients with metastatic testicular tumour. PMID:1282160

  20. APPARENT BIAS IN RIVER WATER INOCULUM FOLLOWING CENTRIFUGATION

    EPA Science Inventory

    We collected four measures of viable bacterial concentration (heterotrophic plate count, total coliform, fecal coliform, and Escherichia coli) and three measures of well color development in Biolog GN2 microtiter plates from water samples that were collected on two or three separ...

  1. Cinematographic analysis of bovine embryo development in serum-free oviduct-conditioned medium.

    PubMed

    Grisart, B; Massip, A; Dessy, F

    1994-07-01

    Development of bovine embryos produced in vitro from the one-cell to the blastocyst stage in serum-free oviduct-conditioned medium was investigated for 8 days consecutively by time-lapse cinematography. Three movies were analysed (130 embryos). The following observations were made. (1) Development under cine-recording conditions was similar to that in a classical incubator. (2) The highest proportion of embryos at the two-cell, three-four-cell, five-eight-cell, 9-16-cell, morula and blastocyst stages were recorded at 34, 46, 61, 115, 149 and 192 h after insemination, respectively. Cleavage asynchrony between blastomeres within individual embryos started at the two-cell stage. (3) The duration of the first three cell cycles was 35 h, 14 h and 11-62 h, respectively. (4) Detailed analysis of 13 embryos revealed that developmental arrest ('Lag-phase') occurred at the four-cell (1 of 13), five-cell (2 of 13), six-cell (3 of 13), seven-cell (3 of 13) or eight-cell stage (4 of 13); this phase lasted about 59 h. Embryos arrested at the eight-cell stage developed into morula-blastocysts (3 of 4) at a higher rate than did those arrested at earlier stages (2 of 9). (5) The faster the embryos cleaved into early stages (two-cell, three-four-cell and five-eight-cell), the higher the probability that they developed into morula-blastocyst: 70% of the embryos reaching the two-cell stage before 30-31 h after insemination developed into morula-blastocyst.(ABSTRACT TRUNCATED AT 250 WORDS)

  2. Treatment of giant intradural (perimedullary) arteriovenous fistulas.

    PubMed

    Halbach, V V; Higashida, R T; Dowd, C F; Fraser, K W; Edwards, M S; Barnwell, S L

    1993-12-01

    Ten patients with giant intradural spinal arteriovenous fistulas (perimedullary Types II and III) were treated with embolization alone (three patients) or in combination with surgery (seven patients). Their ages at the time of treatment ranged from 2 to 40 years, with a mean of 19.5 years. The indications for treatment included progressive myelopathy in five patients, spinal subarachnoid hemorrhage in four, and acute paraplegia in one. Associated conditions included Rendu-Osler-Weber syndrome in two patients, and Cobb's syndrome in two patients. In one patient, the cause of the fistula may have been related to epidural anesthesia traumatizing a low tethered cord. Angiographically, the fistulas were subclassified in three groups: a single-hole fistula supplied by a single feeding medullary artery (three patients); a single-hole fistula supplied by multiple medullary arteries (three patients); and multiple separate fistulas supplied by multiple medullary arteries (four patients). Eight patients were classified as perimedullary Type III and two as perimedullary Type II. Embolic agents were delivered from transarterial routes in 14 procedures and transvenous routes in 2 procedures. A total of 16 embolizations and 8 operations were performed in 10 patients. Seven patients were cured of their fistula (as demonstrated by angiography), two patients had 5% residual filling and are scheduled for future therapy. One refused a follow-up angiographic examination. Complications related to embolization included rupture of the anterior spinal artery by a detachable balloon, resulting in transient worsening of paraplegia with recovery to baseline. Transient worsening of symptoms after surgery was common, but all patients returned to baseline or better. Dramatic improvement was observed in four patients.(ABSTRACT TRUNCATED AT 250 WORDS)

  3. Crusted scabies (sarcoptic mange) in four cats due to Sarcoptes scabiei infestation.

    PubMed

    Malik, Richard; McKellar Stewart, Keith; Sousa, Candace A; Krockenberger, Mark B; Pope, Sally; Ihrke, Peter; Beatty, Julia; Barrs, Vanessa R D; Walton, Shelley

    2006-10-01

    Four new cases of sarcoptic mange in cats are described. Two cats resided in areas known to be frequented by foxes, another cohabited with a dog recently diagnosed with sarcoptic mange, while the final cat lived with a mixed breed dog that had been treated for sarcoptic mange 7 months previously. Three cases were diagnosed on the basis of characteristic mite size and morphology in skin scraping from representative lesions, situated on the head (two cases) or head and distal hind limbs (one case). Mites were highly mobile and abundant in all instances, and easily detected also in skin biopsy specimens procured from two cases. Eosinophilic inflammation, hyperkeratosis and parakeratosis were prominent in the tissue sections. In the remaining case, the diagnosis was presumptive, based on characteristic lesions, cohabitation with a canine scabies patient and positive response to scabicide therapy. Pruritus was not a prominent clinical feature in any patient and was considered to be absent in three of the four cases. Lesions in three cats with long-standing disease were reminiscent of crusted scabies (synonym: Norwegian scabies, parakeratotic scabies) as seen in human patients. In three cases, in-contact human carriers developed itchy cutaneous papular lesions. Two cases responded promptly to therapy with systemic avermectin drugs, while one responded to topical treatment with lime sulphur and the remaining cat received both a lime sulphur rinse and ivermectin. Sarcoptic mange should be considered in the differential diagnosis of cats with non-pruritic crusting skin diseases, especially when there is contact with foxes or dogs, and when owners have itchy papular lesions.

  4. A comparison of several methods of solving nonlinear regression groundwater flow problems

    USGS Publications Warehouse

    Cooley, Richard L.

    1985-01-01

    Computational efficiency and computer memory requirements for four methods of minimizing functions were compared for four test nonlinear-regression steady state groundwater flow problems. The fastest methods were the Marquardt and quasi-linearization methods, which required almost identical computer times and numbers of iterations; the next fastest was the quasi-Newton method, and last was the Fletcher-Reeves method, which did not converge in 100 iterations for two of the problems. The fastest method per iteration was the Fletcher-Reeves method, and this was followed closely by the quasi-Newton method. The Marquardt and quasi-linearization methods were slower. For all four methods the speed per iteration was directly related to the number of parameters in the model. However, this effect was much more pronounced for the Marquardt and quasi-linearization methods than for the other two. Hence the quasi-Newton (and perhaps Fletcher-Reeves) method might be more efficient than either the Marquardt or quasi-linearization methods if the number of parameters in a particular model were large, although this remains to be proven. The Marquardt method required somewhat less central memory than the quasi-linearization metilod for three of the four problems. For all four problems the quasi-Newton method required roughly two thirds to three quarters of the memory required by the Marquardt method, and the Fletcher-Reeves method required slightly less memory than the quasi-Newton method. Memory requirements were not excessive for any of the four methods.

  5. Aggregates and Superaggregates of Soot with Four Distinct Fractal Morphologies

    NASA Technical Reports Server (NTRS)

    Sorensen, C. M.; Kim, W.; Fry, D.; Chakrabarti, A.

    2004-01-01

    Soot formed in laminar diffusion flames of heavily sooting fuels evolves through four distinct growth stages which give rise to four distinct aggregate fractal morphologies. These results were inferred from large and small angle static light scattering from the flames, microphotography of the flames, and analysis of soot sampled from the flames. The growth stages occur approximately over four successive orders of magnitude in aggregate size. Comparison to computer simulations suggests that these four growth stages involve either diffusion limited cluster aggregation or percolation in either three or two dimensions.

  6. Virginia Pine (Pinus virginiana Mill.) Provenanve and Progeny Performance in Oklahoma

    Treesearch

    C.G. Tauer; Syeyd Rashid Hussain Shah; Ronald C. Schmidtling

    1998-01-01

    One hundred and twenty-three open-pollinated families from 38 stands of Virginia pine were tested in Oklahoma. Height and survival data at age 5 for two Christmas tree plantations and at age 5 and 7 for two progenytest plantations were analyzed In the Christmas tree tests, four stands from North Carolina, three from Tennessee, and one each from Alabama, Kentucky, South...

  7. Performance Evaluation of Existing Wedgewater and Vacuum-Assisted Bed Dewatering Systems

    DTIC Science & Technology

    1992-01-01

    prior to dewatering by the wedgewater method. Of the 20 satisfied users, 11 preferred aerobic digestion , two employed anaerobic digestion, and seven...did not further process their sludge. Of the seven dissatisfied users, four used aerobic digestion and three employed anaerobic digestion. A meelic...queried, 11 employed aerobic digestion , two employed anaerobic digestion, and three did not process their sludge. Eight dissatisfied users employed

  8. Children of Two to Three Years of Age in France: Early Childhood Settings and Age Divisions

    ERIC Educational Resources Information Center

    Garnier, Pascale; Rayna, Sylvie; Brougère, Gilles; Rupin, Pablo

    2017-01-01

    In a French early childhood care and education system that is strongly divided by age and institution, the current research studies the collective life of children at the pivotal age of two to three years of age in four different early childhood settings: (1) a group of "grands" (nursery) in a "crèche" (daycare centre), (2) a…

  9. Interannual to Decadal Variability of Atlantic Water in the Nordic and Adjacent Seas

    NASA Technical Reports Server (NTRS)

    Carton, James A.; Chepurin, Gennady A.; Reagan, James; Haekkinen, Sirpa

    2011-01-01

    Warm salty Atlantic Water is the main source water for the Arctic Ocean and thus plays an important role in the mass and heat budget of the Arctic. This study explores interannual to decadal variability of Atlantic Water properties in the Nordic Seas area where Atlantic Water enters the Arctic, based on a reexamination of the historical hydrographic record for the years 1950-2009, obtained by combining multiple data sets. The analysis shows a succession of four multi-year warm events where temperature anomalies at 100m depth exceed 0.4oC, and three cold events. Three of the four warm events lasted 3-4 years, while the fourth began in 1999 and persists at least through 2009. This most recent warm event is anomalous in other ways as well, being the strongest, having the broadest geographic extent, being surface-intensified, and occurring under exceptional meteorological conditions. Three of the four warm events were accompanied by elevated salinities consistent with enhanced ocean transport into the Nordic Seas, with the exception of the event spanning July 1989-July 1993. Of the three cold events, two lasted for four years, while the third lasted for nearly 14 years. Two of the three cold events are associated with reduced salinities, but the cold event of the 1960s had elevated salinities. The relationship of these events to meteorological conditions is examined. The results show that local surface heat flux variations act in some cases to reinforce the anomalies, but are too weak to be the sole cause.

  10. Exploring inter-task transfer following a CO-OP approach with four children with DCD: A single subject multiple baseline design.

    PubMed

    Capistran, Julie; Martini, Rose

    2016-10-01

    Cognitive Orientation to daily Occupational Performance (CO-OP) approach has been shown to be effective for improving the performance of tasks worked on in therapy and the use of cognitive strategies. No study to date seems to have explored its effectiveness for improving performance of untrained tasks (inter-task transfer) in children with Developmental Coordination Disorder (DCD). This study aimed to determine whether CO-OP leads to improved performance in an untrained task. A single-subject design with multiple baselines across skills was adopted, with three replications. Four children with DCD (7-12years) received 10 sessions of CO-OP intervention where each child worked on three tasks during therapy sessions and a fourth task was identified, but not worked on, to verify inter-task transfer. Task performance was rated over four phases (baseline, intervention, post-intervention, follow-up) using the Performance Quality Rating Scale (PQRS-OD). Graphed data was statistically analyzed using a two or three standard deviation band method. Significant improvement was obtained for 11 of 12 tasks worked on during therapy and for two of the four untrained tasks. These results indicate that the effectiveness of CO-OP to improve untrained tasks in children merit further exploration. Copyright © 2016 Elsevier B.V. All rights reserved.

  11. Functional outcome of plate fusions for disorders of the occipitocervical junction.

    PubMed

    Huckell, C B; Buchowski, J M; Richardson, W J; Williams, D; Kostuik, J P

    1999-02-01

    Twenty-eight patients with average followup of 27 months (range, 12-51 months) required occipitocervical fusion with plates. A 1992 to 1996 consecutive case series enrolled patients prospectively from two institutions. Five surgeons participated. Sixteen patients had inflammatory arthritis; four, osteogenesis imperfecta; three, tumors; three, congenital anomalies; one, pseudarthrosis after odontoid fracture; and one, osteoarthritis. Twenty-two of 28 (78.6%) patients had serious comorbid medical conditions. Additional halo immobilization of 6 weeks was used in 16 of 27 patients. Four patients required revision surgery. No patients showed a decline in neurologic status and average neurologic improvement was one Nurick grade. Two-year followup showed 13 (50%) excellent, nine (34.6%) good, two (7.7%) fair, and two (7.7%) poor outcomes based on a functional outcome scale. There were three deaths during the followup period (overall mortality rate of 10.7%). One death was attributable to airway obstruction, one death 14 months postoperatively was attributable to late Methicillin resistant Staphylococcus aureus sepsis at the bone graft donor site, and one death 41 months postoperatively was attributable to a stroke. The overall fusion rate was 85.2% (23 of 27 patients), with a 96.3% (26 of 27 patients) occipitocervical fusion rate. Three patients had a possible asymptomatic end segment pseudarthrosis with screw loosening. Twenty-two of 26 (84.6%) interviewed patients would choose the surgery again if given the choice.

  12. Modeling Primary Breakup: A Three-Dimensional Eulerian Level Set/Vortex Sheet Method for Two-Phase Interface Dynamics

    NASA Technical Reports Server (NTRS)

    Herrmann, M.

    2003-01-01

    This paper is divided into four parts. First, the level set/vortex sheet method for three-dimensional two-phase interface dynamics is presented. Second, the LSS model for the primary breakup of turbulent liquid jets and sheets is outlined and all terms requiring subgrid modeling are identified. Then, preliminary three-dimensional results of the level set/vortex sheet method are presented and discussed. Finally, conclusions are drawn and an outlook to future work is given.

  13. RELATIONSHIP BETWEEN RIGIDITY OF EXTERNAL FIXATOR AND NUMBER OF PINS: COMPUTER ANALYSIS USING FINITE ELEMENTS

    PubMed Central

    Sternick, Marcelo Back; Dallacosta, Darlan; Bento, Daniela Águida; do Reis, Marcelo Lemos

    2015-01-01

    Objective: To analyze the rigidity of a platform-type external fixator assembly, according to different numbers of pins on each clamp. Methods: Computer simulation on a large-sized Cromus dynamic external fixator (Baumer SA) was performed using a finite element method, in accordance with the standard ASTM F1541. The models were generated with approximately 450,000 quadratic tetrahedral elements. Assemblies with two, three and four Schanz pins of 5.5 mm in diameter in each clamp were compared. Every model was subjected to a maximum force of 200 N, divided into 10 sub-steps. For the components, the behavior of the material was assumed to be linear, elastic, isotropic and homogeneous. For each model, the rigidity of the assembly and the Von Mises stress distribution were evaluated. Results: The rigidity of the system was 307.6 N/mm for two pins, 369.0 N/mm for three and 437.9 N/mm for four. Conclusion: The results showed that four Schanz pins in each clamp promoted rigidity that was 19% greater than in the configuration with three pins and 42% greater than with two pins. Higher tension occurred in configurations with fewer pins. In the models analyzed, the maximum tension occurred on the surface of the pin, close to the fixation area. PMID:27047879

  14. Late onset familial dystonia: could mitochondrial deficits induce a diffuse lesioning process of the whole basal ganglia system?

    PubMed Central

    Caparros-Lefebvre, D; Destee, A; Petit, H

    1997-01-01

    BACKGROUND—Striatal necrosis has been related to various clinical syndromes, with acute or chronic progression, and juvenile or late occurrence, but the most common type is Leigh's encephalopathy.
METHODS—Between 1967 and 1995, six out of seven related patients with chronic familial dystonia were examined. MRIs were performed in four, between 1992-1994. The seven members, affected over three generations, were the father, three daughters (one surviving), and three surviving grandsons.
RESULTS—The leading symptoms were gait disorders and dystonia in all, dysarthria in six, verbal and motor stereotypies in two, and parkinsonian and cerebellar signs in three. Optic neuropathy was found in three. A frontal lobe syndrome without amnesia occurred in two. Symptoms occurred between the second and the fifth decade, with progressive deterioration. Magnetic resonance imaging, performed in four, showed in the two patients with severe neurological signs diffuse striatopallidal abnormal hyposignal (comparable with CSF signal) in T1 weighted images, suggesting extensive necrosis of the striatum and pallidum, associated with thalamo-subthalamo-rubro-dentato-nigral and substantia innominata hypersignals in T2 weighted images suggesting gliosis in these respective areas. The same images were described to a lesser extent in a third patient. Concentrations of lactate in CSF and serum were normal in three. Muscle biopsy, performed in four, was shown to be normal. Enzyme histochemistry showed complex I, III, and IV deficiency in surviving patients.
CONCLUSION—This familial dystonia of chronic progression may be related to basal ganglia necrosis or gliosis, associated with alterations in the respiratory chain. These metabolic alterations probably play a part in the pathophysiology of these unusual brain lesions.

 PMID:9285458

  15. Subject-independent emotion recognition based on physiological signals: a three-stage decision method.

    PubMed

    Chen, Jing; Hu, Bin; Wang, Yue; Moore, Philip; Dai, Yongqiang; Feng, Lei; Ding, Zhijie

    2017-12-20

    Collaboration between humans and computers has become pervasive and ubiquitous, however current computer systems are limited in that they fail to address the emotional component. An accurate understanding of human emotions is necessary for these computers to trigger proper feedback. Among multiple emotional channels, physiological signals are synchronous with emotional responses; therefore, analyzing physiological changes is a recognized way to estimate human emotions. In this paper, a three-stage decision method is proposed to recognize four emotions based on physiological signals in the multi-subject context. Emotion detection is achieved by using a stage-divided strategy in which each stage deals with a fine-grained goal. The decision method consists of three stages. During the training process, the initial stage transforms mixed training subjects to separate groups, thus eliminating the effect of individual differences. The second stage categorizes four emotions into two emotion pools in order to reduce recognition complexity. The third stage trains a classifier based on emotions in each emotion pool. During the testing process, a test case or test trial will be initially classified to a group followed by classification into an emotion pool in the second stage. An emotion will be assigned to the test trial in the final stage. In this paper we consider two different ways of allocating four emotions into two emotion pools. A comparative analysis is also carried out between the proposal and other methods. An average recognition accuracy of 77.57% was achieved on the recognition of four emotions with the best accuracy of 86.67% to recognize the positive and excited emotion. Using differing ways of allocating four emotions into two emotion pools, we found there is a difference in the effectiveness of a classifier on learning each emotion. When compared to other methods, the proposed method demonstrates a significant improvement in recognizing four emotions in the multi-subject context. The proposed three-stage decision method solves a crucial issue which is 'individual differences' in multi-subject emotion recognition and overcomes the suboptimal performance with respect to direct classification of multiple emotions. Our study supports the observation that the proposed method represents a promising methodology for recognizing multiple emotions in the multi-subject context.

  16. [Four infants with upper urinary tract infection due to extended-spectrum bata lactamase (ESBL)-producing Escherichia coli].

    PubMed

    Hibino, Satoshi; Fukuchi, Kunihiko; Abe, Yoshifusa; Hoshino, Akihiro; Sakurai, Shunsuke; Mikawa, Takeshi; Fuke, Toshiya; Yoshida, Koichiro; Itabashi, Kazuo

    2011-09-01

    Bacteria producing extended-spectrum beta lactamase (ESBL) are detected mainly in adult urinary specimens, and are believed to cause hospital-acquired infection due to their resistance to many drugs. The incidence of community-acquired infection due to such bacteria is increasing, but few cases of infant upper urinary tract infection (UUTI) have been reported in Japan. We treated four infants with UUTI caused by ESBL-producing Escherichia coli, as determined by genotyping. Using medical records, we retrospectively evaluated the clinical course, antibiotic use and efficacy, antimicrobial susceptibility results, and the presence of underlying disease. One of the four had been previously hospitalized for occult bacteremia. Two developed UUTI after antibiotic treatment, indicating that previous antibiotic use may have been a risk factor in these cases. We could not identify the infection route in all cases. Two of the four had bilateral vesicoureteral reflux (VUR). Renal scintigraphy was done in three. Although an initial dimercaptosuccinic acid (DMSA) defect was detected in all four, only one had renal scarring. E. coli isolates from all four showed PCR signals for blaCTX-M-; one isolate positive for the blaCTX-M3 group and three positive for blaCTX-M14. Antimicrobial susceptibility test results showed all isolates to be resistant to cephalosporins, but discrepancies existed between antimicrobial susceptibility results and actual clinical efficacy. Clinically, cefazolin (CEZ) was effective in two subjects and ceftazidime (CAZ) effective in one. Panipenem/betamipron (PAPM/BP) was effective in one. None of the four developed sepsis or meningitis. Post hospitalization antibiotic prophylaxis showed that none of the four has had UUTI recur. Japan's ESBL-producing bacterial infection incidence is increasing, so medical professionals should watch for such UUTI even in first-case occurrence in infants.

  17. Single phase four pole/six pole motor

    DOEpatents

    Kirschbaum, Herbert S.

    1984-01-01

    A single phase alternating current electric motor is provided with a main stator winding having two coil groups each including the series connection of three coils. These coil groups can be connected in series for six pole operation and in parallel for four pole operation. The coils are approximately equally spaced around the periphery of the machine but are not of equal numbers of turns. The two coil groups are identically wound and spaced 180 mechanical degrees apart. One coil of each group has more turns and a greater span than the other two coils.

  18. The primary structure of stinging nettle (Urtica dioica) agglutinin. A two-domain member of the hevein family.

    PubMed

    Beintema, J J; Peumans, W J

    1992-03-09

    The primary structure of stinging nettle (Urtica dioica) agglutinin has been determined by sequence analysis of peptides obtained from three overlapping proteolytic digests. The sequence of 80 residues consists of two hevein-like domains with the same spacing of half-cystine residues and several other conserved residues as observed earlier in other proteins with hevein-like domains. The hinge region between the two domains is four residues longer than those between the four domains in cereal lectins like wheat germ agglutinin.

  19. A new balancing three level three dimensional space vector modulation strategy for three level neutral point clamped four leg inverter based shunt active power filter controlling by nonlinear back stepping controllers.

    PubMed

    Chebabhi, Ali; Fellah, Mohammed Karim; Kessal, Abdelhalim; Benkhoris, Mohamed F

    2016-07-01

    In this paper is proposed a new balancing three-level three dimensional space vector modulation (B3L-3DSVM) strategy which uses a redundant voltage vectors to realize precise control and high-performance for a three phase three-level four-leg neutral point clamped (NPC) inverter based Shunt Active Power Filter (SAPF) for eliminate the source currents harmonics, reduce the magnitude of neutral wire current (eliminate the zero-sequence current produced by single-phase nonlinear loads), and to compensate the reactive power in the three-phase four-wire electrical networks. This strategy is proposed in order to gate switching pulses generation, dc bus voltage capacitors balancing (conserve equal voltage of the two dc bus capacitors), and to switching frequency reduced and fixed of inverter switches in same times. A Nonlinear Back Stepping Controllers (NBSC) are used for regulated the dc bus voltage capacitors and the SAPF injected currents to robustness, stabilizing the system and to improve the response and to eliminate the overshoot and undershoot of traditional PI (Proportional-Integral). Conventional three-level three dimensional space vector modulation (C3L-3DSVM) and B3L-3DSVM are calculated and compared in terms of error between the two dc bus voltage capacitors, SAPF output voltages and THDv, THDi of source currents, magnitude of source neutral wire current, and the reactive power compensation under unbalanced single phase nonlinear loads. The success, robustness, and the effectiveness of the proposed control strategies are demonstrated through simulation using Sim Power Systems and S-Function of MATLAB/SIMULINK. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

  20. Human transinformation rates during one-to-four axis tracking with a concurrent audio task

    NASA Technical Reports Server (NTRS)

    Baty, D. L.

    1972-01-01

    The information processing rates of six subjects performing one-, two-, three-, and four-axis compensatory tracking tasks, with and without a concurrent four-choice auditory task were determined. The purpose was to obtain further evidence concerning the nature of an hypothesized ceiling on human transinformation rates. Interference was found among tasks, but the evidence concerning a ceiling on information processing rates was inconclusive.

  1. GRIN1 mutations cause encephalopathy with infantile-onset epilepsy, and hyperkinetic and stereotyped movement disorders.

    PubMed

    Ohba, Chihiro; Shiina, Masaaki; Tohyama, Jun; Haginoya, Kazuhiro; Lerman-Sagie, Tally; Okamoto, Nobuhiko; Blumkin, Lubov; Lev, Dorit; Mukaida, Souichi; Nozaki, Fumihito; Uematsu, Mitsugu; Onuma, Akira; Kodera, Hirofumi; Nakashima, Mitsuko; Tsurusaki, Yoshinori; Miyake, Noriko; Tanaka, Fumiaki; Kato, Mitsuhiro; Ogata, Kazuhiro; Saitsu, Hirotomo; Matsumoto, Naomichi

    2015-06-01

    Recently, de novo mutations in GRIN1 have been identified in patients with nonsyndromic intellectual disability and epileptic encephalopathy. Whole exome sequencing (WES) analysis of patients with genetically unsolved epileptic encephalopathies identified four patients with GRIN1 mutations, allowing us to investigate the phenotypic spectrum of GRIN1 mutations. Eighty-eight patients with unclassified early onset epileptic encephalopathies (EOEEs) with an age of onset <1 year were analyzed by WES. The effect of mutations on N-methyl-D-aspartate (NMDA) receptors was examined by mapping altered amino acids onto three-dimensional models. We identified four de novo missense GRIN1 mutations in 4 of 88 patients with unclassified EOEEs. In these four patients, initial symptoms appeared within 3 months of birth, including hyperkinetic movements in two patients (2/4, 50%), and seizures in two patients (2/4, 50%). Involuntary movements, severe developmental delay, and intellectual disability were recognized in all four patients. In addition, abnormal eye movements resembling oculogyric crises and stereotypic hand movements were observed in two and three patients, respectively. All the four patients exhibited only nonspecific focal and diffuse epileptiform abnormality, and never showed suppression-burst or hypsarrhythmia during infancy. A de novo mosaic mutation (c.1923G>A) with a mutant allele frequency of 16% (in DNA of blood leukocytes) was detected in one patient. Three mutations were located in the transmembrane domain (3/4, 75%), and one in the extracellular loop near transmembrane helix 1. All the mutations were predicted to impair the function of the NMDA receptor. Clinical features of de novo GRIN1 mutations include infantile involuntary movements, seizures, and hand stereotypies, suggesting that GRIN1 mutations cause encephalopathy resulting in seizures and movement disorders. Wiley Periodicals, Inc. © 2015 International League Against Epilepsy.

  2. Road diet informational guide.

    DOT National Transportation Integrated Search

    2014-11-01

    A classic Road Diet converts an existing four-lane undivided roadway segment to a three-lane segment consisting of two : through lanes and a center two-way left turn lane (TWLTL). A Road Diet improves safety by including a protected left-turn lane : ...

  3. International Space Station (ISS)

    NASA Image and Video Library

    2001-05-08

    This is the insignia for the STS-108 mission, which marked a major milestone in the assembly of the International Space Station (ISS) as the first designated Utilization Flight, UF-1. The crew of Endeavour delivered the Expedition Four crew to ISS and returned the Expedition Three crew to Earth. Endeavour launched with a Multi-Purpose Logistics Module (MPLM) that was berthed to the ISS and unloaded. The MPLM was returned to Endeavour for the trip home and used again on a later flight. The crew patch depicts Endeavour and the ISS in the configuration at the time of arrival and docking. The Station is shown viewed along the direction of flight as seen by the Shuttle crew during their final approach and docking along the X-axis. The three ribbons and stars on the left side of the patch signify the returning Expedition Three crew. The red, white and blue order of the ribbons represents the American commander for that mission. The three ribbons and stars on the right depict the arriving Expedition Four crew. The white, blue, and red order of the Expedition Four ribbon matches the color of the Russian flag and signifies that the commander of Expedition Four is a Russian cosmonaut. Each white star in the center of the patch represents the four Endeavour crew members. The names of the four astronauts who crewed Endeavour are shown along the top border of the patch. The three astronauts and three cosmonauts of the two expedition crews are shown on the chevron at the bottom of the patch.

  4. Two-loop renormalization of quantum gravity simplified

    NASA Astrophysics Data System (ADS)

    Bern, Zvi; Chi, Huan-Hang; Dixon, Lance; Edison, Alex

    2017-02-01

    The coefficient of the dimensionally regularized two-loop R3 divergence of (nonsupersymmetric) gravity theories has recently been shown to change when nondynamical three-forms are added to the theory, or when a pseudoscalar is replaced by the antisymmetric two-form field to which it is dual. This phenomenon involves evanescent operators, whose matrix elements vanish in four dimensions, including the Gauss-Bonnet operator which is also connected to the trace anomaly. On the other hand, these effects appear to have no physical consequences for renormalized scattering processes. In particular, the dependence of the two-loop four-graviton scattering amplitude on the renormalization scale is simple. We explain this result for any minimally-coupled massless gravity theory with renormalizable matter interactions by using unitarity cuts in four dimensions and never invoking evanescent operators.

  5. Noninvasive treatment alternative for intractable startle epilepsy

    PubMed Central

    Klinkenberg, Sylvia; Ubbink, Sander; Vles, Johannes; de Louw, Anton; van Hall, Mariette Debeij; Scheijen, Dyon; Brokx, Jan

    2014-01-01

    We describe a treatment alternative for intractable, startle-provoked, epileptic seizures in four children aged between 8 and 14. Three of the four children had symptomatic localization-related epilepsy. They all suffered from intractable epilepsy precipitated by sudden sounds. The fact that seizures tended to occur with high frequency – more than one seizure a day – had a clear impact on daily life. Clinical seizure pattern demonstrated asymmetric tonic posturing in all four children. Three children experienced several seizure types including focal seizure onset. All children had focal neurological signs or learning disabilities or a combination of both. Our noninvasive treatment method using psychoeducational counseling and sound generators was applied in four children, resulting in a seizure frequency reduction of ≥ 50% in two of them. PMID:25667869

  6. Nonpharmacological treatments for patients with Parkinson's disease.

    PubMed

    Bloem, Bastiaan R; de Vries, Nienke M; Ebersbach, Georg

    2015-09-15

    Since 2013, a number of studies have enhanced the literature and have guided clinicians on viable treatment interventions outside of pharmacotherapy and surgery. Thirty-three randomized controlled trials and one large observational study on exercise and physiotherapy were published in this period. Four randomized controlled trials focused on dance interventions, eight on treatment of cognition and behavior, two on occupational therapy, and two on speech and language therapy (the latter two specifically addressed dysphagia). Three randomized controlled trials focused on multidisciplinary care models, one study on telemedicine, and four studies on alternative interventions, including music therapy and mindfulness. These studies attest to the marked interest in these therapeutic approaches and the increasing evidence base that places nonpharmacological treatments firmly within the integrated repertoire of treatment options in Parkinson's disease. © 2015 International Parkinson and Movement Disorder Society.

  7. Multitasking a three-dimensional Navier-Stokes algorithm on the Cray-2

    NASA Technical Reports Server (NTRS)

    Swisshelm, Julie M.

    1989-01-01

    A three-dimensional computational aerodynamics algorithm has been multitasked for efficient parallel execution on the Cray-2. It provides a means for examining the multitasking performance of a complete CFD application code. An embedded zonal multigrid scheme is used to solve the Reynolds-averaged Navier-Stokes equations for an internal flow model problem. The explicit nature of each component of the method allows a spatial partitioning of the computational domain to achieve a well-balanced task load for MIMD computers with vector-processing capability. Experiments have been conducted with both two- and three-dimensional multitasked cases. The best speedup attained by an individual task group was 3.54 on four processors of the Cray-2, while the entire solver yielded a speedup of 2.67 on four processors for the three-dimensional case. The multiprocessing efficiency of various types of computational tasks is examined, performance on two Cray-2s with different memory access speeds is compared, and extrapolation to larger problems is discussed.

  8. Exchange donor transplantation: ethical option for living renal transplantation.

    PubMed

    Gürkan, A; Kaçar, S; Varılsuha, C; Tilif, S; Turunç, V; Doǧan, M; Dheir, H; Sahin, S

    2011-04-01

    Taking in consideration the opinion of our team, which necessitates obligation of a relative relation between donors and recipients (genetic or matrimonial), we performed donor exchanges as an ethical alternative in living donor transplantations. We reviewed the outcomes of our exchange series. Between July 2003 and August 2010 we performed 110 exchange donor transplantations in four hospitals: one four-way, two three-way, and 100 two-way cases. Donors were mostly spouses (n = 71) or mothers (n = 15). The mean age of the donors was 48.8 (range = 23-69) and the recipients 41.4 years (range = 5-66). Two were transplanted preemptively and the others had a mean dialysis duration of 43 months (range = 1-120). Among 110 patients, three compatible pairs joined the group voluntarily; 71, due to ABO incompatibility and 36, due to crossmatch positivity. Induction therapy was used in 92 patients. HLA mismatches (MM) were: one MM in three; two MM in three; three MM in 18, four MM in 36; five MM in 34; and six MM in 18. Among 90 patients tested for panel-reactive antibodies PRA, five showed class I and 10, class II positivity. In 11 patients, B-cell positivity was detected by flow cytometry. Delayed graft function (n = 2), acute rejection (n = 11), BK virus infection (n = 1), and cytomegalovirus infection (n = 3) were seen postoperatively. Three (2.7%) patients died due to sepsis. Five patients returned to dialysis program due to interstitial fibrosis tubular atrophy (IFTA) (n = 2), renal vein thrombosis (n = 1), de novo glomerulopathy (n = 1), or primary nonfunction (n = 1). The 1- and 5-year patient and graft survival rates were 96% and 96%, 95% and 89%, respectively. We believe that exchange donor transplantation is as successful as direct transplants; it is a good, ethical alternative to unrelated living transplantations. Copyright © 2011 Elsevier Inc. All rights reserved.

  9. Chemical investigation of predator-deterred macroalgae from the Antarctic peninsula.

    PubMed

    Ankisetty, Sridevi; Nandiraju, Santhisree; Win, Hla; Park, Young Chul; Amsler, Charles D; McClintock, James B; Baker, Jill A; Diyabalanage, Thushara K; Pasaribu, Albert; Singh, Maya P; Maiese, William M; Walsh, Rosa D; Zaworotko, Michael J; Baker, Bill J

    2004-08-01

    Chemical investigation of five Antarctic macroalgae whose tissues and crude extracts displayed ecologically relevant feeding deterrence in field bioassays was performed. Eleven compounds were characterized from the three red algae studied, of which four (1-3 and 9) were previously unreported, and four compounds were found from two brown algae, two (12 and 14) of which are new natural products. Several of these pure compounds have been individually investigated in ecological and/or pharmacological bioassays.

  10. Pigeons' Discrimination of Michotte's Launching Effect

    ERIC Educational Resources Information Center

    Young, Michael E.; Beckmann, Joshua S.; Wasserman, Edward A.

    2006-01-01

    We trained four pigeons to discriminate a Michotte launching animation from three other animations using a go/no-go task. The pigeons received food for pecking at one of the animations, but not for pecking at the others. The four animations featured two types of interactions among objects: causal (direct launching) and noncausal (delayed, distal,…

  11. Confirmatory Factor Analysis of the WISC-III with Child Psychiatric Inpatients.

    ERIC Educational Resources Information Center

    Tupa, David J.; Wright, Margaret O'Dougherty; Fristad, Mary A.

    1997-01-01

    Factor models of the Wechsler Intelligence Scale for Children-Third Edition (WISC-III) for one, two, three, and four factors were tested using confirmatory factor analysis with a sample of 177 child psychiatric inpatients. The four-factor model proposed in the WISC-III manual provided the best fit to the data. (SLD)

  12. Closing the Gap. SREB Program Blends Academic Standards, Vocational Courses.

    ERIC Educational Resources Information Center

    Bottoms, Gene

    1992-01-01

    Southern Regional Education Board's State Vocational Education Consortium developed a model for integrating vocational and academic education that includes at least three credits each in math and science; four English courses; and four credits in a vocational major and two in related fields. Eight sites implementing the model have narrowed gap…

  13. Multi-Institutional Assessment of Adverse Health Outcomes Among North American Testicular Cancer Survivors After Modern Cisplatin-Based Chemotherapy

    PubMed Central

    Fung, Chunkit; Sesso, Howard D.; Williams, Annalynn M.; Kerns, Sarah L.; Monahan, Patrick; Abu Zaid, Mohammad; Feldman, Darren R.; Hamilton, Robert J.; Vaughn, David J.; Beard, Clair J.; Kollmannsberger, Christian K.; Cook, Ryan; Althouse, Sandra; Ardeshir-Rouhani-Fard, Shirin; Lipshultz, Steve E.; Fossa, Sophie D.; Travis, Lois B.

    2017-01-01

    Purpose To provide new information on adverse health outcomes (AHOs) in testicular cancer survivors (TCSs) after four cycles of etoposide and cisplatin (EPX4) or three or four cycles of bleomycin, etoposide, cisplatin (BEPX3/BEPX4). Methods Nine hundred fifty-two TCSs > 1 year postchemotherapy underwent physical examination and completed a questionnaire. Multinomial logistic regression estimated AHOs odds ratios (ORs) in relation to age, cumulative cisplatin and/or bleomycin dose, time since chemotherapy, sociodemographic factors, and health behaviors. Results Median age at evaluation was 37 years; median time since chemotherapy was 4.3 years. Chemotherapy consisted largely of BEPX3 (38.2%), EPX4 (30.9%), and BEPX4 (17.9%). None, one to two, three to four, or five or more AHOs were reported by 20.4%, 42.0%, 25.1%, and 12.5% of TCSs, respectively. Median number after EPX4 or BEPX3 was two (range, zero to nine and zero to 11, respectively; P > .05) and two (range, zero to 10) after BEPX4. When comparing individual AHOs for EPX4 versus BEPX3, Raynaud phenomenon (11.6% v 21.4%; P < .01), peripheral neuropathy (29.2% v 21.4%; P = .02), and obesity (25.5% v 33.0%; P = .04) differed. Larger cumulative bleomycin doses (OR, 1.44 per 90,000 IU) were significantly associated with five or more AHOs. Increasing age was a significant risk factor for one to two, three to four, or five or more AHOs versus zero AHOs (OR, 1.22, 1.50, and 1.87 per 5 years, respectively; P < .01); vigorous physical activity was protective (OR, 0.62, 0.51, and 0.41, respectively; P < .05). Significant risk factors for three to four and five or more AHOs included current (OR, 3.05 and 3.73) or former (OR, 1.61 and 1.76) smoking (P < .05). Self-reported health was excellent/very good in 59.9% of TCSs but decreased as AHOs increased (P < .001). Conclusion Numbers of AHOs after EPX4 or BEPX3 appear similar, with median follow-up of 4.3 years. A healthy lifestyle was associated with reduced number of AHOs. PMID:28240972

  14. Effects of ocean acidification on the shells of four Mediterranean gastropod species near a CO2 seep.

    PubMed

    Duquette, Ashley; McClintock, James B; Amsler, Charles D; Pérez-Huerta, Alberto; Milazzo, Marco; Hall-Spencer, Jason M

    2017-11-30

    Marine CO 2 seeps allow the study of the long-term effects of elevated pCO 2 (ocean acidification) on marine invertebrate biomineralization. We investigated the effects of ocean acidification on shell composition and structure in four ecologically important species of Mediterranean gastropods (two limpets, a top-shell snail, and a whelk). Individuals were sampled from three sites near a volcanic CO 2 seep off Vulcano Island, Italy. The three sites represented ambient (8.15pH), moderate (8.03pH) and low (7.73pH) seawater mean pH. Shell mineralogy, microstructure, and mechanical strength were examined in all four species. We found that the calcite/aragonite ratio could vary and increased significantly with reduced pH in shells of one of the two limpet species. Moreover, each of the four gastropods displayed reductions in either inner shell toughness or elasticity at the Low pH site. These results suggest that near-future ocean acidification could alter shell biomineralization and structure in these common gastropods. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Time-fixed rendezvous by impulse factoring with an intermediate timing constraint. [for transfer orbits

    NASA Technical Reports Server (NTRS)

    Green, R. N.; Kibler, J. F.; Young, G. R.

    1974-01-01

    A method is presented for factoring a two-impulse orbital transfer into a three- or four-impulse transfer which solves the rendezvous problem and satisfies an intermediate timing constraint. Both the time of rendezvous and the intermediate time of a alinement are formulated as any element of a finite sequence of times. These times are integer multiples of a constant plus an additive constant. The rendezvous condition is an equality constraint, whereas the intermediate alinement is an inequality constraint. The two timing constraints are satisfied by factoring the impulses into collinear parts that vectorially sum to the original impulse and by varying the resultant period differences and the number of revolutions in each orbit. Five different types of solutions arise by considering factoring either or both of the two impulses into two or three parts with a limit for four total impulses. The impulse-factoring technique may be applied to any two-impulse transfer which has distinct orbital periods.

  16. Compartmental analysis of [11C]flumazenil kinetics for the estimation of ligand transport rate and receptor distribution using positron emission tomography.

    PubMed

    Koeppe, R A; Holthoff, V A; Frey, K A; Kilbourn, M R; Kuhl, D E

    1991-09-01

    The in vivo kinetic behavior of [11C]flumazenil ([11C]FMZ), a non-subtype-specific central benzodiazepine antagonist, is characterized using compartmental analysis with the aim of producing an optimized data acquisition protocol and tracer kinetic model configuration for the assessment of [11C]FMZ binding to benzodiazepine receptors (BZRs) in human brain. The approach presented is simple, requiring only a single radioligand injection. Dynamic positron emission tomography data were acquired on 18 normal volunteers using a 60- to 90-min sequence of scans and were analyzed with model configurations that included a three-compartment, four-parameter model, a three-compartment, three-parameter model, with a fixed value for free plus nonspecific binding; and a two-compartment, two-parameter model. Statistical analysis indicated that a four-parameter model did not yield significantly better fits than a three-parameter model. Goodness of fit was improved for three- versus two-parameter configurations in regions with low receptor density, but not in regions with moderate to high receptor density. Thus, a two-compartment, two-parameter configuration was found to adequately describe the kinetic behavior of [11C]FMZ in human brain, with stable estimates of the model parameters obtainable from as little as 20-30 min of data. Pixel-by-pixel analysis yields functional images of transport rate (K1) and ligand distribution volume (DV"), and thus provides independent estimates of ligand delivery and BZR binding.

  17. Once or twice daily versus three times daily amoxicillin with or without clavulanate for the treatment of acute otitis media.

    PubMed

    Thanaviratananich, Sanguansak; Laopaiboon, Malinee; Vatanasapt, Patravoot

    2013-12-13

    Acute otitis media (AOM) is a common problem in children, for which amoxicillin, with or without clavulanate, is frequently prescribed as a treatment of choice. The conventional recommendation is either three or four daily doses. However, nowadays it is frequently prescribed as once or twice daily doses. If once or twice daily amoxicillin, with or without clavulanate, is as effective for acute otitis media as three or four times a day, it may be more convenient to give the medication once or twice a day to children and hence improve compliance. To compare the effectiveness of one or two daily doses with three or four daily doses of amoxicillin, with or without clavulanate, for the treatment of AOM in children; and to compare complication rates and adverse reactions. We searched CENTRAL 2013, Issue 2, MEDLINE (January 1950 to March week 1, 2013), EMBASE (1974 to March 2013) and the Science Citation Index (2001 to March 2013). We included randomised controlled trials (RCTs) of children aged 12 years or younger with AOM, diagnosed by acute ear pain (otalgia) and inflamed ear drum (confirmed by positive tympanocentesis or tympanogram of type B or C). Two review authors independently extracted data on treatment outcomes from individual trials and assessed trial quality based on selection bias, performance bias and detection bias, attrition bias, reporting bias and other biases. We defined the quality grading as low risk of bias, high risk of bias or unclear risk of bias. We summarised the results as risk ratio (RR) with 95% confidence intervals (CI). We included five studies with 1601 children in the review. Pooled analysis demonstrated that the following outcomes were comparable between the two groups: clinical cure at the end of therapy (RR 1.03, 95% CI 0.99 to 1.07); during therapy (RR 1.06, 95% CI 0.85 to 1.33) and at follow-up (RR 1.02, 95% CI 0.95 to 1.09); recurrent AOM (RR 1.21, 95% CI 0.52 to 2.81); compliance rate (RR 1.04, 95% CI 0.98 to 1.10) and overall adverse events (RR 0.92, 95% CI 0.52 to 1.63). When we performed subgroup analysis separately for trials with amoxicillin only and amoxicillin/clavulanate only, it showed that all important outcomes were comparable between once or twice daily groups and the three times daily group. The risk of bias amongst the five included studies was as follows: for random sequence generation we graded two studies as low and three unclear risk of bias; for allocation concealment all studies were at unclear risk of bias; for blinding (performance and detection bias) we graded four as high and one as unclear risk of bias; for incomplete outcome data (attrition bias) we graded two low, two high and one as unclear risk of bias; for reporting bias four were at low and one at high risk; and for 'other' bias four were at low and one at unclear risk of bias. This review showed that the results of using once or twice daily doses of amoxicillin, with or without clavulanate, were comparable with three doses for the treatment of AOM.

  18. Three essays on energy and economic growth

    NASA Astrophysics Data System (ADS)

    Peach, Nathanael David

    2011-12-01

    This dissertation explores the relationship between energy and economic growth. Chapter Two, Three, and Four examine the interaction of energy-related measures and economic outcomes by applying different methodologies across various spatial dimensions. Chapter Two shows that increases in energy consumption are necessary for increases in state level economic growth to occur. Chapter Three estimates a simultaneous supply and demand energy market at the state level. This system allows for estimates of structural elasticities to be obtained. Findings indicate that energy supply is considerably more elastic than energy demand. Energy demand is found to be determined by responses to short run shocks rather than long run processes. Chapter Four estimates the impact of changes in various elements of governance and institutional quality impact genuine investment within an economy. Increases in democracy are predicted to decrease genuine investment in energy-rich nations. The dissertation concludes with Chapter Five.

  19. Evolutionary games combining two or three pair coordinations on a square lattice

    NASA Astrophysics Data System (ADS)

    Király, Balázs; Szabó, György

    2017-10-01

    We study multiagent logit-rule-driven evolutionary games on a square lattice whose pair interactions are composed of a maximal number of nonoverlapping elementary coordination games describing Ising-type interactions between just two of the available strategies. Using Monte Carlo simulations we investigate the macroscopic noise-level-dependent behavior of the two- and three-pair games and the critical properties of the continuous phase transtitions these systems exhibit. The four-strategy game is shown to be equivalent to a system that consists of two independent and identical Ising models.

  20. Evolutionary games combining two or three pair coordinations on a square lattice.

    PubMed

    Király, Balázs; Szabó, György

    2017-10-01

    We study multiagent logit-rule-driven evolutionary games on a square lattice whose pair interactions are composed of a maximal number of nonoverlapping elementary coordination games describing Ising-type interactions between just two of the available strategies. Using Monte Carlo simulations we investigate the macroscopic noise-level-dependent behavior of the two- and three-pair games and the critical properties of the continuous phase transtitions these systems exhibit. The four-strategy game is shown to be equivalent to a system that consists of two independent and identical Ising models.

  1. Pump CFD code validation tests

    NASA Technical Reports Server (NTRS)

    Brozowski, L. A.

    1993-01-01

    Pump CFD code validation tests were accomplished by obtaining nonintrusive flow characteristic data at key locations in generic current liquid rocket engine turbopump configurations. Data were obtained with a laser two-focus (L2F) velocimeter at scaled design flow. Three components were surveyed: a 1970's-designed impeller, a 1990's-designed impeller, and a four-bladed unshrouded inducer. Two-dimensional velocities were measured upstream and downstream of the two impellers. Three-dimensional velocities were measured upstream, downstream, and within the blade row of the unshrouded inducer.

  2. A discussion of the several types of two-stroke-cycle engines

    NASA Technical Reports Server (NTRS)

    Venediger, Herbert J

    1935-01-01

    This report discusses different types of two-stroke engines as well as the three most important design factors: volume of scavenge and charge delivery, scavenging process (scavenging result), and result of charge. Some of the types of engines discussed include: single cylinder with crank-chamber scavenge pump and auxiliary suction piston linked to working connecting rod; and two cylinder engines with a rotary scavenge pump arrangement. Three and four cylinder engines are also discussed in various designs.

  3. Optical switching property of electromagnetically induced transparency in a Λ system

    NASA Astrophysics Data System (ADS)

    Zhang, Lianshui; Wang, Jian; Feng, Xiaomin; Yang, Lijun; Li, Xiaoli; Zhao, Min

    2008-12-01

    In this paper we study the coherent transient property of a Λ-three-level system (Ωd = 0) and a quasi- Λ -four-level system (Ωd>0). Optical switching of the probe field can be achieved by applying a pulsed coupling field or rf field. In Λ -shaped three-level system, when the coupling field was switched on, there is a almost total transparency of the probe field and the time required for the absorption changing from 90% to 10% of the maximum absorption is 2.9Γ0 (Γ0 is spontaneous emission lifetime). When the coupling field was switched off, there is an initial increase of the probe field absorption and then gradually evolves to the maximum of absorption of the two-level absorption, the time required for the absorption of the system changing from 10% to 90% is 4.2Γ0. In four-level system, where rf driving field is used as switching field, to achieve the same depth of the optical switching, the time of the optical switching is 2.5Γ0 and 6.1Γ0, respectively. The results show that with the same depth of the optical switching, the switch-on time of the four-level system is shorter than that of the three-level system, while the switch-off time of the four-level system is longer. The depth of the optical switching of the four-level system was much larger than that of the three-level system, where the depth of the optical switching of the latter is merely 14.8% of that of the former. The speed of optical switching of the two systems can be increased by the increase of Rabi frequency of coupling field or rf field.

  4. Interleaved power converter

    DOEpatents

    Zhu, Lizhi

    2007-11-13

    A power converter architecture interleaves full bridge converters to alleviate thermal management problems in high current applications, and may, for example, double the output power capability while reducing parts count and costs. For example, one phase of a three phase inverter is shared between two transformers, which provide power to a rectifier such as a current doubler rectifier to provide two full bridge DC/DC converters with three rather than four high voltage inverter legs.

  5. 20. INTERIOR OF BEDROOM NUMBER THREE SHOWING OPEN DOOR TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. INTERIOR OF BEDROOM NUMBER THREE SHOWING OPEN DOOR TO THE LIVING ROOM AT PHOTO LEFT, CLOSED PANEL DOOR TO WALK-IN CLOSET AT PHOTO CENTER LEFT, AND OPEN PANEL DOOR TO BATHROOM NUMBER TWO AT PHOTO RIGHT. OPEN DOOR TO BATHROOM NUMER TWO LOOKS THROUGH TO BEDROOM NUMBER FOUR. VIEW TO SOUTHEAST. - Rush Creek Hydroelectric System, Clubhouse Cottage, Rush Creek, June Lake, Mono County, CA

  6. [Appearance of hepatitis B in a family environment].

    PubMed

    Marinković, V; Letica, Z; Zivanović-Marinković, V; Mijusković, P; Kapulica, I; Dokić, M

    1981-01-01

    The study comprised 20 families with total of 83 members of whom 45 with hepatitis B. The selection was made of families with at least two members diseased which was the most common case, the marital couples being in question. Of other families, three families had three members and one family four members with hepatitis B virus infection. The largest number had severe clinical picture (44%) and 13 (28%) chronic active hepatitis. Four patients with the most severe clinical picture of chronic active hepatitis, together with HBeantigens, had positive HBeantigen for more than two years since the onset of the disease. Importance of damaged skin and mucosa in spreading of hepatitis B infection in family environment has been pointed out.

  7. Entanglement of two, three, or four plasmonically coupled quantum dots

    NASA Astrophysics Data System (ADS)

    Otten, Matthew; Shah, Raman A.; Scherer, Norbert F.; Min, Misun; Pelton, Matthew; Gray, Stephen K.

    2015-09-01

    We model the quantum dynamics of two, three, or four quantum dots (QDs) in proximity to a plasmonic system such as a metal nanoparticle or an array of metal nanoparticles. For all systems, an initial state with only one QD in its excited state evolves spontaneously into a state with entanglement between all pairs of QDs. The entanglement arises from the couplings of the QDs to the dissipative, plasmonic environment. Moreover, we predict that similarly entangled states can be generated in systems with appropriate geometries, starting in their ground states, by exciting the entire system with a single, ultrafast laser pulse. By using a series of repeated pulses, the system can also be prepared in an entangled state at an arbitrary time.

  8. Semivolatile and Volatile Organic Compound Emissions from Wood-Fired Hydronic Heaters

    EPA Science Inventory

    Four commercially available HH technologies were studied: a single-stage combustor with natural updraft, a three-stage downdraft combustion system, a bottom-fed pellet burner, and a two-stage heater with both a combustion and gasification chamber. The fuel consisted of three wood...

  9. Effect of neoadjuvant chemotherapy on resectability of stage III and IV hepatoblastoma.

    PubMed

    Venkatramani, R; Stein, J E; Sapra, A; Genyk, Y; Jhaveri, V; Malogolowkin, M; Mascarenhas, L

    2015-01-01

    The potential for surgical resection of primary hepatoblastoma tumours was assessed at diagnosis, and after two and four cycles of neoadjuvant chemotherapy. Available radiographic images for patients with stage III and IV hepatoblastoma diagnosed between 1991 and 2008 were reviewed. The extent of disease was determined at diagnosis using the PRETEXT staging system, and after two and four cycles of therapy by POST-TEXT staging. Tumour resectability based on radiographic studies was assessed independently by two surgeons with expertise in hepatic surgery who were blinded to treatment and clinical outcome. Radiographic images from 20 patients with hepatoblastoma were reviewed. Six of 20 tumours were downstaged after two cycles, and three additional tumours were downstaged following four cycles. All PRETEXT stage III and IV tumours were determined to be surgically unresectable at diagnosis. The number of tumours considered unresectable decreased from 16 of 20 at diagnosis to seven of 20 after two cycles, and to four of 20 after four cycles. Five of the seven tumours that were unresectable after two cycles, and all four tumours that were unresectable after four cycles would have qualified for liver transplant based on radiographic studies. The majority of stage III and IV hepatoblastomas achieved radiographic resectability after two cycles of chemotherapy. There may be an opportunity for earlier surgical intervention and potential for a reduction in chemotherapy in a considerable number of patients. © 2014 BJS Society Ltd. Published by John Wiley & Sons Ltd.

  10. Effects of antithrombotic drugs in patients with left ventricular thrombi: assessment with indium-111 platelet imaging and two-dimensional echocardiography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stratton, J.R.; Ritchie, J.L.

    Patients with left ventricular thrombi not caused by recent myocardial infarction were prospectively studied by indium-111 platelet imaging and two-dimensional echocardiography to determine the reproducibility of these techniques and the short-term effects of sulfinpyrazone (200 mg four times daily), aspirin (325 mg three times daily) plus dipyridamole (75 mg three times daily), and full-dose warfarin. At baseline, all patients underwent indium-111 platelet imaging and echocardiography, and the results were positive for thrombus. In six patients on no antithrombotic drug therapy, repeat platelet scans and echocardiographic studies at 6.0 +/- 3.3 weeks remained positive and were unchanged. In seven patients studiedmore » on sulfinpyrazone, three platelet scans became negative, two became equivocal, and two were unchanged; the presence and size of thrombus was constant by echocardiography in all seven patients. Of the six patients studied on aspirin plus dipyridamole, one platelet scan became negative, those of three became equivocal, and two were unchanged; all echocardiographic findings remained positive, but one patient had decreased thrombus size. Among four warfarin-treated patients, three had resolution of platelet deposition and one was unchanged; by echocardiography, thrombus resolved in one patient, was decreased in size in one, and was unchanged in two. We conclude that, in the absence of antithrombotic drug therapy, platelet imaging and echocardiographic findings are stable in patients with left ventricular thrombi not caused by recent myocardial infarction. Sulfinpyrazone, aspirin plus dipyridamole, and warfarin all interrupt platelet deposition in some patients with chronic left ventricular thrombi.« less

  11. Part-time occlusion therapy for amblyopia in older children.

    PubMed

    Singh, Inderpreet; Sachdev, Nishant; Brar, Gagandeep S; Kaushik, Sushmita

    2008-01-01

    To compare the efficacy of part-time versus full-time occlusion for treatment of amblyopia in children aged 7-12 years. Prospective interventional case series. One hundred children between 7-12 years of age with anisometropic (57), strabismic (25) and mixed (18) unilateral amblyopia were randomized (simple randomization) into four groups (25 each) to receive two hours, four hours, six hours or full-time occlusion therapy. Children were regularly followed up at six-weekly intervals for a minimum of three visits. Intragroup visual improvement was analyzed using paired t-test while intergroup comparisons were done using ANOVA and unpaired t-test. All four groups showed significant visual improvement after 18 weeks of occlusion therapy ( P < 0.001). Seventy-three (73%) of the total 100 eyes responded to amblyopia therapy with 11 eyes (44%), 17 eyes (68%), 22 eyes (88%) and 23 eyes (92%) being amblyopia responders in the four groups respectively, with the least number of responders in the two hours group. In mild to moderate amblyopia (vision 20/30 to 20/80), there was no significant difference in visual outcome among the four groups ( P =0.083). However, in severe amblyopia (vision 20/100 or worse), six hours ( P =0.048) and full-time occlusion ( P =0.027) treatment were significantly more effective than two hours occlusion. All grades of part-time occlusion are comparable to full-time occlusion in effectiveness of treatment for mild to moderate amblyopia in children between 7-12 years of age unlike in severe amblyopia, where six hours and full-time occlusion were more effective than two hours occlusion therapy.

  12. Occupational exposure to pesticides and respiratory health.

    PubMed

    Mamane, Ali; Baldi, Isabelle; Tessier, Jean-François; Raherison, Chantal; Bouvier, Ghislaine

    2015-06-01

    This article aims to review the available literature regarding the link between occupational exposure to pesticides and respiratory symptoms or diseases. Identification of epidemiological studies was performed using PubMed. 41 articles were included, 36 regarding agricultural workers and five regarding industry workers. Among the 15 cross-sectional studies focusing on respiratory symptoms and agricultural pesticide exposure, 12 found significant associations with chronic cough, wheeze, dyspnoea, breathlessness or chest tightness. All four studies on asthma found a relationship with occupational exposure, as did all three studies on chronic bronchitis. The four studies that performed spirometry reported impaired respiratory function linked to pesticide exposure, suggestive of either obstructive or restrictive syndrome according to the chemical class of pesticide. 12 papers reported results from cohort studies. Three out of nine found a significant relationship with increased risk of wheeze, five out of nine with asthma and three out of three with chronic bronchitis. In workers employed in pesticide production, elevated risks of chronic obstructive pulmonary disease (two studies out of three) and impaired respiratory function suggestive of an obstructive syndrome (two studies out of two) were reported. In conclusion, this article suggests that occupational exposure to pesticides is associated with an increased risk of respiratory symptoms, asthma and chronic bronchitis, but the causal relationship is still under debate. Copyright ©ERS 2015.

  13. Prediction of supercritical ethane bulk solvent densities for pyrazine solvation shell average occupancy by 1, 2, 3, and 4 ethanes: combined experimental and ab initio approach.

    PubMed

    Hrnjez, Bruce J; Sultan, Samuel T; Natanov, Georgiy R; Kastner, David B; Rosman, Michael R

    2005-11-17

    We introduce a method that addresses the elusive local density at the solute in the highly compressible regime of a supercritical fluid. Experimentally, the red shift of the pyrazine n-pi electronic transition was measured at infinite dilution in supercritical ethane as a function of pressure from 0 to about 3000 psia at two temperatures, one close (35.0 degrees C) to the critical temperature and the other remote (55.0 degrees C). Computationally, stationary points were located on the potential surfaces for pyrazine and one, two, three, and four ethanes at the MP2/6-311++G(d,p) level. The vertical n-pi ((1)B(3u)) transition energies were computed for each of these geometries with a TDDFT/B3LYP/6-311++G(d,p) method. The combination of experiment and computation allows prediction of supercritical ethane bulk densities at which the pyrazine primary solvation shell contains an average of one, two, three, and four ethane molecules. These density predictions were achieved by graphical superposition of calculated shifts on the experimental shift versus density curves for 35.0 and 55.0 degrees C. Predicted densities are 0.0635, 0.0875, and 0.0915 g cm(-3) for average pyrazine primary solvation shell occupancy by one, two, and three ethanes at both 35.0 and 55.0 degrees C. Predicted densities are 0.129 and 0.150 g cm(-3) for occupancy by four ethanes at 35.0 and 55.0 degrees C, respectively. An alternative approach, designed to "average out" geometry specific shifts, is based on the relationship Deltanu = -23.9n cm(-1), where n = ethane number. Graphical treatment gives alternative predicted densities of 0.0490, 0.0844, and 0.120 g cm(-3) for average pyrazine primary solvation shell occupancy by one, two, and three ethanes at both 35.0 and 55.0 degrees C, and densities of 0.148 and 0.174 g cm(-3) for occupancy by four ethanes at 35.0 and 55.0 degrees C, respectively.

  14. Earth-approaching asteroid streams

    NASA Astrophysics Data System (ADS)

    Drummond, J. D.

    1991-01-01

    Three association patterns have been noted among 139 earth-approaching asteroids on the basis of current orbital similarity; these asteroid streams, consisting of two groups of five members and one of four, can be matched to three of the four meteorite-producing fireball streams determined by Halliday et al. (1990). If the asteroid streams are true nonrandom associations, the opportunity arises for studies of an 'exploded' asteroid in the near-earth environment. Near-earth asteroid-search projects are encouraged to search the mean orbit of the present streams in order to discover additional association members.

  15. Distributions of topological observables in inclusive three- and four-jet events in pp collisions at

    NASA Astrophysics Data System (ADS)

    Khachatryan, V.; Sirunyan, A. M.; Tumasyan, A.; Adam, W.; Bergauer, T.; Dragicevic, M.; Erö, J.; Friedl, M.; Frühwirth, R.; Ghete, V. M.; Hartl, C.; Hörmann, N.; Hrubec, J.; Jeitler, M.; Kiesenhofer, W.; Knünz, V.; Krammer, M.; Krätschmer, I.; Liko, D.; Mikulec, I.; Rabady, D.; Rahbaran, B.; Rohringer, H.; Schöfbeck, R.; Strauss, J.; Treberer-Treberspurg, W.; Waltenberger, W.; Wulz, C.-E.; Mossolov, V.; Shumeiko, N.; Suarez Gonzalez, J.; Alderweireldt, S.; Bansal, S.; Cornelis, T.; De Wolf, E. A.; Janssen, X.; Knutsson, A.; Lauwers, J.; Luyckx, S.; Ochesanu, S.; Rougny, R.; Van De Klundert, M.; Van Haevermaet, H.; Van Mechelen, P.; Van Remortel, N.; Van Spilbeeck, A.; Blekman, F.; Blyweert, S.; D'Hondt, J.; Daci, N.; Heracleous, N.; Keaveney, J.; Lowette, S.; Maes, M.; Olbrechts, A.; Python, Q.; Strom, D.; Tavernier, S.; Van Doninck, W.; Van Mulders, P.; Van Onsem, G. P.; Villella, I.; Caillol, C.; Clerbaux, B.; De Lentdecker, G.; Dobur, D.; Favart, L.; Gay, A. P. R.; Grebenyuk, A.; Léonard, A.; Mohammadi, A.; Perniè, L.; Randle-conde, A.; Reis, T.; Seva, T.; Thomas, L.; Vander Velde, C.; Vanlaer, P.; Wang, J.; Zenoni, F.; Adler, V.; Beernaert, K.; Benucci, L.; Cimmino, A.; Costantini, S.; Crucy, S.; Dildick, S.; Fagot, A.; Garcia, G.; Mccartin, J.; Ocampo Rios, A. A.; Ryckbosch, D.; Salva Diblen, S.; Sigamani, M.; Strobbe, N.; Thyssen, F.; Tytgat, M.; Yazgan, E.; Zaganidis, N.; Basegmez, S.; Beluffi, C.; Bruno, G.; Castello, R.; Caudron, A.; Ceard, L.; Da Silveira, G. G.; Delaere, C.; du Pree, T.; Favart, D.; Forthomme, L.; Giammanco, A.; Hollar, J.; Jafari, A.; Jez, P.; Komm, M.; Lemaitre, V.; Nuttens, C.; Pagano, D.; Perrini, L.; Pin, A.; Piotrzkowski, K.; Popov, A.; Quertenmont, L.; Selvaggi, M.; Vidal Marono, M.; Vizan Garcia, J. M.; Beliy, N.; Caebergs, T.; Daubie, E.; Hammad, G. H.; Júnior, W. L. Aldá; Alves, G. A.; Brito, L.; Correa Martins Junior, M.; Martins, T. Dos Reis; Mora Herrera, C.; Pol, M. E.; Rebello Teles, P.; Carvalho, W.; Chinellato, J.; Custódio, A.; Da Costa, E. M.; De Jesus Damiao, D.; De Oliveira Martins, C.; Fonseca De Souza, S.; Malbouisson, H.; Matos Figueiredo, D.; Mundim, L.; Nogima, H.; Prado Da Silva, W. L.; Santaolalla, J.; Santoro, A.; Sznajder, A.; Tonelli Manganote, E. J.; Vilela Pereira, A.; Bernardes, C. A.; Dogra, S.; Fernandez Perez Tomei, T. R.; Gregores, E. M.; Mercadante, P. G.; Novaes, S. F.; Padula, Sandra S.; Aleksandrov, A.; Genchev, V.; Hadjiiska, R.; Iaydjiev, P.; Marinov, A.; Piperov, S.; Rodozov, M.; Sultanov, G.; Vutova, M.; Dimitrov, A.; Glushkov, I.; Litov, L.; Pavlov, B.; Petkov, P.; Bian, J. G.; Chen, G. M.; Chen, H. S.; Chen, M.; Cheng, T.; Du, R.; Jiang, C. H.; Plestina, R.; Romeo, F.; Tao, J.; Wang, Z.; Asawatangtrakuldee, C.; Ban, Y.; Li, Q.; Liu, S.; Mao, Y.; Qian, S. J.; Wang, D.; Xu, Z.; Zou, W.; Avila, C.; Cabrera, A.; Chaparro Sierra, L. F.; Florez, C.; Gomez, J. P.; Gomez Moreno, B.; Sanabria, J. C.; Godinovic, N.; Lelas, D.; Polic, D.; Puljak, I.; Antunovic, Z.; Kovac, M.; Brigljevic, V.; Kadija, K.; Luetic, J.; Mekterovic, D.; Sudic, L.; Attikis, A.; Mavromanolakis, G.; Mousa, J.; Nicolaou, C.; Ptochos, F.; Razis, P. A.; Bodlak, M.; Finger, M.; Finger, M.; Assran, Y.; Ellithi Kamel, A.; Mahmoud, M. A.; Radi, A.; Kadastik, M.; Murumaa, M.; Raidal, M.; Tiko, A.; Eerola, P.; Fedi, G.; Voutilainen, M.; Härkönen, J.; Karimäki, V.; Kinnunen, R.; Kortelainen, M. J.; Lampén, T.; Lassila-Perini, K.; Lehti, S.; Lindén, T.; Luukka, P.; Mäenpää, T.; Peltola, T.; Tuominen, E.; Tuominiemi, J.; Tuovinen, E.; Wendland, L.; Talvitie, J.; Tuuva, T.; Besancon, M.; Couderc, F.; Dejardin, M.; Denegri, D.; Fabbro, B.; Faure, J. L.; Favaro, C.; Ferri, F.; Ganjour, S.; Givernaud, A.; Gras, P.; Hamel de Monchenault, G.; Jarry, P.; Locci, E.; Malcles, J.; Rander, J.; Rosowsky, A.; Titov, M.; Baffioni, S.; Beaudette, F.; Busson, P.; Charlot, C.; Dahms, T.; Dalchenko, M.; Dobrzynski, L.; Filipovic, N.; Florent, A.; Granier de Cassagnac, R.; Mastrolorenzo, L.; Miné, P.; Mironov, C.; Naranjo, I. N.; Nguyen, M.; Ochando, C.; Ortona, G.; Paganini, P.; Regnard, S.; Salerno, R.; Sauvan, J. B.; Sirois, Y.; Veelken, C.; Yilmaz, Y.; Zabi, A.; Agram, J.-L.; Andrea, J.; Aubin, A.; Bloch, D.; Brom, J.-M.; Chabert, E. C.; Collard, C.; Conte, E.; Fontaine, J.-C.; Gelé, D.; Goerlach, U.; Goetzmann, C.; Le Bihan, A.-C.; Skovpen, K.; Van Hove, P.; Gadrat, S.; Beauceron, S.; Beaupere, N.; Boudoul, G.; Bouvier, E.; Brochet, S.; Carrillo Montoya, C. A.; Chasserat, J.; Chierici, R.; Contardo, D.; Depasse, P.; El Mamouni, H.; Fan, J.; Fay, J.; Gascon, S.; Gouzevitch, M.; Ille, B.; Kurca, T.; Lethuillier, M.; Mirabito, L.; Perries, S.; Ruiz Alvarez, J. D.; Sabes, D.; Sgandurra, L.; Sordini, V.; Vander Donckt, M.; Verdier, P.; Viret, S.; Xiao, H.; Tsamalaidze, Z.; Autermann, C.; Beranek, S.; Bontenackels, M.; Edelhoff, M.; Feld, L.; Heister, A.; Hindrichs, O.; Klein, K.; Ostapchuk, A.; Raupach, F.; Sammet, J.; Schael, S.; Schulte, J. F.; Weber, H.; Wittmer, B.; Zhukov, V.; Ata, M.; Brodski, M.; Dietz-Laursonn, E.; Duchardt, D.; Erdmann, M.; Fischer, R.; Güth, A.; Hebbeker, T.; Heidemann, C.; Hoepfner, K.; Klingebiel, D.; Knutzen, S.; Kreuzer, P.; Merschmeyer, M.; Meyer, A.; Millet, P.; Olschewski, M.; Padeken, K.; Papacz, P.; Reithler, H.; Schmitz, S. A.; Sonnenschein, L.; Teyssier, D.; Thüer, S.; Weber, M.; Cherepanov, V.; Erdogan, Y.; Flügge, G.; Geenen, H.; Geisler, M.; Haj Ahmad, W.; Hoehle, F.; Kargoll, B.; Kress, T.; Kuessel, Y.; Künsken, A.; Lingemann, J.; Nowack, A.; Nugent, I. M.; Pooth, O.; Stahl, A.; Aldaya Martin, M.; Asin, I.; Bartosik, N.; Behr, J.; Behrens, U.; Bell, A. J.; Bethani, A.; Borras, K.; Burgmeier, A.; Cakir, A.; Calligaris, L.; Campbell, A.; Choudhury, S.; Costanza, F.; Diez Pardos, C.; Dolinska, G.; Dooling, S.; Dorland, T.; Eckerlin, G.; Eckstein, D.; Eichhorn, T.; Flucke, G.; Garcia, J. Garay; Geiser, A.; Gunnellini, P.; Hauk, J.; Hempel, M.; Jung, H.; Kalogeropoulos, A.; Kasemann, M.; Katsas, P.; Kieseler, J.; Kleinwort, C.; Korol, l.; Krücker, D.; Lange, W.; Leonard, J.; Lipka, K.; Lobanov, A.; Lohmann, W.; Lutz, B.; Mankel, R.; Marfin, I.; Melzer-Pellmann, I.-A.; Meyer, A. B.; Mittag, G.; Mnich, J.; Mussgiller, A.; Naumann-Emme, S.; Nayak, A.; Ntomari, E.; Perrey, H.; Pitzl, D.; Placakyte, R.; Raspereza, A.; Ribeiro Cipriano, P. M.; Roland, B.; Ron, E.; Sahin, M. Ö.; Salfeld-Nebgen, J.; Saxena, P.; Schoerner-Sadenius, T.; Schröder, M.; Seitz, C.; Spannagel, S.; Vargas Trevino, A. D. R.; Walsh, R.; Wissing, C.; Blobel, V.; Centis Vignali, M.; Draeger, A. R.; Erfle, J.; Garutti, E.; Goebel, K.; Görner, M.; Haller, J.; Hoffmann, M.; Höing, R. S.; Junkes, A.; Kirschenmann, H.; Klanner, R.; Kogler, R.; Lange, J.; Lapsien, T.; Lenz, T.; Marchesini, I.; Ott, J.; Peiffer, T.; Perieanu, A.; Pietsch, N.; Poehlsen, J.; Poehlsen, T.; Rathjens, D.; Sander, C.; Schettler, H.; Schleper, P.; Schlieckau, E.; Schmidt, A.; Seidel, M.; Sola, V.; Stadie, H.; Steinbrück, G.; Troendle, D.; Usai, E.; Vanelderen, L.; Vanhoefer, A.; Barth, C.; Baus, C.; Berger, J.; Böser, C.; Butz, E.; Chwalek, T.; De Boer, W.; Descroix, A.; Dierlamm, A.; Feindt, M.; Frensch, F.; Giffels, M.; Gilbert, A.; Hartmann, F.; Hauth, T.; Husemann, U.; Katkov, I.; Kornmayer, A.; Kuznetsova, E.; Lobelle Pardo, P.; Mozer, M. U.; Müller, T.; Müller, Th.; Nürnberg, A.; Quast, G.; Rabbertz, K.; Röcker, S.; Simonis, H. J.; Stober, F. M.; Ulrich, R.; Wagner-Kuhr, J.; Wayand, S.; Weiler, T.; Wolf, R.; Anagnostou, G.; Daskalakis, G.; Geralis, T.; Giakoumopoulou, V. A.; Kyriakis, A.; Loukas, D.; Markou, A.; Markou, C.; Psallidas, A.; Topsis-Giotis, I.; Agapitos, A.; Kesisoglou, S.; Panagiotou, A.; Saoulidou, N.; Stiliaris, E.; Aslanoglou, X.; Evangelou, I.; Flouris, G.; Foudas, C.; Kokkas, P.; Manthos, N.; Papadopoulos, I.; Paradas, E.; Strologas, J.; Bencze, G.; Hajdu, C.; Hidas, P.; Horvath, D.; Sikler, F.; Veszpremi, V.; Vesztergombi, G.; Zsigmond, A. J.; Beni, N.; Czellar, S.; Karancsi, J.; Molnar, J.; Palinkas, J.; Szillasi, Z.; Makovec, A.; Raics, P.; Trocsanyi, Z. L.; Ujvari, B.; Swain, S. K.; Beri, S. B.; Bhatnagar, V.; Gupta, R.; Bhawandeep, U.; Kalsi, A. K.; Kaur, M.; Kumar, R.; Mittal, M.; Nishu, N.; Singh, J. B.; Kumar, Ashok; Kumar, Arun; Ahuja, S.; Bhardwaj, A.; Choudhary, B. C.; Kumar, A.; Malhotra, S.; Naimuddin, M.; Ranjan, K.; Sharma, V.; Banerjee, S.; Bhattacharya, S.; Chatterjee, K.; Dutta, S.; Gomber, B.; Jain, Sa.; Jain, Sh.; Khurana, R.; Modak, A.; Mukherjee, S.; Roy, D.; Sarkar, S.; Sharan, M.; Abdulsalam, A.; Dutta, D.; Kumar, V.; Mohanty, A. K.; Pant, L. M.; Shukla, P.; Topkar, A.; Aziz, T.; Banerjee, S.; Bhowmik, S.; Chatterjee, R. M.; Dewanjee, R. K.; Dugad, S.; Ganguly, S.; Ghosh, S.; Guchait, M.; Gurtu, A.; Kole, G.; Kumar, S.; Maity, M.; Majumder, G.; Mazumdar, K.; Mohanty, G. B.; Parida, B.; Sudhakar, K.; Wickramage, N.; Bakhshiansohi, H.; Behnamian, H.; Etesami, S. M.; Fahim, A.; Goldouzian, R.; Khakzad, M.; Mohammadi Najafabadi, M.; Naseri, M.; Paktinat Mehdiabadi, S.; Rezaei Hosseinabadi, F.; Safarzadeh, B.; Zeinali, M.; Felcini, M.; Grunewald, M.; Abbrescia, M.; Calabria, C.; Chhibra, S. S.; Colaleo, A.; Creanza, D.; De Filippis, N.; De Palma, M.; Fiore, L.; Iaselli, G.; Maggi, G.; Maggi, M.; My, S.; Nuzzo, S.; Pompili, A.; Pugliese, G.; Radogna, R.; Selvaggi, G.; Sharma, A.; Silvestris, L.; Venditti, R.; Verwilligen, P.; Abbiendi, G.; Benvenuti, A. C.; Bonacorsi, D.; Braibant-Giacomelli, S.; Brigliadori, L.; Campanini, R.; Capiluppi, P.; Castro, A.; Cavallo, F. R.; Codispoti, G.; Cuffiani, M.; Dallavalle, G. M.; Fabbri, F.; Fanfani, A.; Fasanella, D.; Giacomelli, P.; Grandi, C.; Guiducci, L.; Marcellini, S.; Masetti, G.; Montanari, A.; Navarria, F. L.; Perrotta, A.; Rossi, A. M.; Primavera, F.; Rovelli, T.; Siroli, G. P.; Tosi, N.; Travaglini, R.; Albergo, S.; Cappello, G.; Chiorboli, M.; Costa, S.; Giordano, F.; Potenza, R.; Tricomi, A.; Tuve, C.; Barbagli, G.; Ciulli, V.; Civinini, C.; D'Alessandro, R.; Focardi, E.; Gallo, E.; Gonzi, S.; Gori, V.; Lenzi, P.; Meschini, M.; Paoletti, S.; Sguazzoni, G.; Tropiano, A.; Benussi, L.; Bianco, S.; Fabbri, F.; Piccolo, D.; Ferretti, R.; Ferro, F.; Lo Vetere, M.; Robutti, E.; Tosi, S.; Dinardo, M. E.; Fiorendi, S.; Gennai, S.; Gerosa, R.; Ghezzi, A.; Govoni, P.; Lucchini, M. T.; Malvezzi, S.; Manzoni, R. A.; Martelli, A.; Marzocchi, B.; Menasce, D.; Moroni, L.; Paganoni, M.; Pedrini, D.; Ragazzi, S.; Redaelli, N.; Tabarelli de Fatis, T.; Buontempo, S.; Cavallo, N.; Di Guida, S.; Fabozzi, F.; Iorio, A. O. M.; Lista, L.; Meola, S.; Merola, M.; Paolucci, P.; Azzi, P.; Bacchetta, N.; Bellato, M.; Biasotto, M.; Dall'Osso, M.; Dorigo, T.; Galanti, M.; Giubilato, P.; Gonella, F.; Gozzelino, A.; Kanishchev, K.; Lacaprara, S.; Margoni, M.; Meneguzzo, A. T.; Montecassiano, F.; Passaseo, M.; Pazzini, J.; Pegoraro, M.; Pozzobon, N.; Ronchese, P.; Simonetto, F.; Torassa, E.; Tosi, M.; Vanini, S.; Ventura, S.; Zotto, P.; Zucchetta, A.; Gabusi, M.; Ratti, S. P.; Re, V.; Riccardi, C.; Salvini, P.; Vitulo, P.; Biasini, M.; Bilei, G. M.; Ciangottini, D.; Fanò, L.; Lariccia, P.; Mantovani, G.; Menichelli, M.; Saha, A.; Santocchia, A.; Spiezia, A.; Androsov, K.; Azzurri, P.; Bagliesi, G.; Bernardini, J.; Boccali, T.; Broccolo, G.; Castaldi, R.; Ciocci, M. A.; Dell'Orso, R.; Donato, S.; Fedi, G.; Fiori, F.; Foà, L.; Giassi, A.; Grippo, M. T.; Ligabue, F.; Lomtadze, T.; Martini, L.; Messineo, A.; Moon, C. S.; Palla, F.; Rizzi, A.; Savoy-Navarro, A.; Serban, A. T.; Spagnolo, P.; Squillacioti, P.; Tenchini, R.; Tonelli, G.; Venturi, A.; Verdini, P. G.; Vernieri, C.; Barone, L.; Cavallari, F.; D'imperio, G.; Del Re, D.; Diemoz, M.; Jorda, C.; Longo, E.; Margaroli, F.; Meridiani, P.; Micheli, F.; Nourbakhsh, S.; Organtini, G.; Paramatti, R.; Rahatlou, S.; Rovelli, C.; Santanastasio, F.; Soffi, L.; Traczyk, P.; Amapane, N.; Arcidiacono, R.; Argiro, S.; Arneodo, M.; Bellan, R.; Biino, C.; Cartiglia, N.; Casasso, S.; Costa, M.; Degano, A.; Demaria, N.; Finco, L.; Mariotti, C.; Maselli, S.; Migliore, E.; Monaco, V.; Musich, M.; Obertino, M. M.; Pacher, L.; Pastrone, N.; Pelliccioni, M.; Pinna Angioni, G. L.; Potenza, A.; Romero, A.; Ruspa, M.; Sacchi, R.; Solano, A.; Staiano, A.; Tamponi, U.; Belforte, S.; Candelise, V.; Casarsa, M.; Cossutti, F.; Della Ricca, G.; Gobbo, B.; La Licata, C.; Marone, M.; Schizzi, A.; Umer, T.; Zanetti, A.; Chang, S.; Kropivnitskaya, T. A.; Nam, S. K.; Kim, D. H.; Kim, G. N.; Kim, M. S.; Kim, M. S.; Kong, D. J.; Lee, S.; Oh, Y. D.; Park, H.; Sakharov, A.; Son, D. C.; Kim, T. J.; Kim, J. 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R.; Faulkner, J.; Kovitanggoon, K.; Kunori, S.; Lee, S. W.; Libeiro, T.; Volobouev, I.; Appelt, E.; Delannoy, A. G.; Greene, S.; Gurrola, A.; Johns, W.; Maguire, C.; Mao, Y.; Melo, A.; Sharma, M.; Sheldon, P.; Snook, B.; Tuo, S.; Velkovska, J.; Arenton, M. W.; Boutle, S.; Cox, B.; Francis, B.; Goodell, J.; Hirosky, R.; Ledovskoy, A.; Li, H.; Lin, C.; Neu, C.; Wood, J.; Clarke, C.; Harr, R.; Karchin, P. E.; Kottachchi Kankanamge Don, C.; Lamichhane, P.; Sturdy, J.; Belknap, D. A.; Carlsmith, D.; Cepeda, M.; Dasu, S.; Dodd, L.; Duric, S.; Friis, E.; Hall-Wilton, R.; Herndon, M.; Hervé, A.; Klabbers, P.; Lanaro, A.; Lazaridis, C.; Levine, A.; Loveless, R.; Mohapatra, A.; Ojalvo, I.; Perry, T.; Pierro, G. A.; Polese, G.; Ross, I.; Sarangi, T.; Savin, A.; Smith, W. H.; Taylor, D.; Vuosalo, C.; Woods, N.

    2015-07-01

    This paper presents distributions of topological observables in inclusive three- and four-jet events produced in pp collisions at a centre-of-mass energy of 7 with a data sample collected by the CMS experiment corresponding to a luminosity of 5.1. The distributions are corrected for detector effects, and compared with several event generators based on two- and multi-parton matrix elements at leading order. Among the considered calculations, MadGraph interfaced with pythia6 displays the overall best agreement with data.

  16. On non-primitively divergent vertices of Yang-Mills theory

    NASA Astrophysics Data System (ADS)

    Huber, Markus Q.

    2017-11-01

    Two correlation functions of Yang-Mills beyond the primitively divergent ones, the two-ghost-two-gluon and the four-ghost vertices, are calculated and their influence on lower vertices is examined. Their full (transverse) tensor structure is taken into account. As input, a solution of the full two-point equations - including two-loop terms - is used that respects the resummed perturbative ultraviolet behavior. A clear hierarchy is found with regard to the color structure that reduces the number of relevant dressing functions. The impact of the two-ghost-two-gluon vertex on the three-gluon vertex is negligible, which is explained by the fact that all non-small dressing functions drop out due to their color factors. Only in the ghost-gluon vertex a small net effect below 2% is seen. The four-ghost vertex is found to be extremely small in general. Since these two four-point functions do not enter into the propagator equations, these findings establish their small overall effect on lower correlation functions.

  17. Clinical features of congenital portosystemic shunt in children.

    PubMed

    Kim, Myung Jin; Ko, Jae Sung; Seo, Jeong Kee; Yang, Hye Ran; Chang, Ju Young; Kim, Gi Beom; Cheon, Jung-Eun; Kim, Woo Sun

    2012-02-01

    Clinical features, images, complications, treatments, and prognosis of 10 children with congenital portosystemic shunt (CPSS) were reviewed. Nine children were diagnosed with intrahepatic shunts while one presented with extrahepatic shunt. CPSS was detected by prenatal ultrasonography in four infants. Three infants presented with galactosemia without an enzyme deficiency. Two children presented with mental retardation and attention deficit hyperactivity disorder. Pulmonary hypertension developed in two patients. Spontaneous closure occurred in four infants with intrahepatic shunts including patent ductus venosus. The shunts were closed using transcatheter embolizations in four patients with intrahepatic shunts. Intrahepatic shunts may close spontaneously. Transcatheter embolization is effective for the treatment of symptomatic intrahepatic shunts.

  18. Cancer-prone syndrome of mosaic variegated aneuploidy and total premature chromatid separation: report of five infants.

    PubMed

    Kajii, T; Ikeuchi, T; Yang, Z Q; Nakamura, Y; Tsuji, Y; Yokomori, K; Kawamura, M; Fukuda, S; Horita, S; Asamoto, A

    2001-11-15

    Five infants (two girls and three boys) from four families all had severe pre- and postnatal growth retardation, profound developmental delay, microcephaly, hypoplasia of the brain with Dandy-Walker complex or other posterior fossa malformations, and developed uncontrollable clonic seizures. Four infants developed Wilms tumors, and one showed cystic lesions in bilateral kidneys. All five infants showed variegated mosaic aneuploidy in cultured lymphocytes. In two infants whose chromosomes were prepared by us, 48.5%-83.2% lymphocytes showed total premature chromatid separation (PCS). Their parents had 3.5%-41.7% of their lymphocytes in total PCS. The remaining three infants and their parents, whose chromosomes were prepared at outside laboratories, tended to show lower frequencies of total PCS. Another five infants reported with the disorder were reviewed together with the five infants we described. Together, their clinical and cytogenetic manifestations were similar enough to suggest a syndrome. Seven of the 10 infants developed proven or probable Wilms tumors. The age at diagnosis of the tumors was younger than usual at 2-16 months. The tumors were bilateral in four infants and unilateral in three infants, and cystic changes were present in six infants. Two infants developed botryoid rhabdomyosarcoma. The carriers of the syndrome are thus liable to tumorigenesis. The possible role of mitotic checkpoint defects, proven in two infants with the syndrome (Matsuura et al. [2000: Am J Hum Genet 69:483-486]), was discussed in connection with tumor development and progression. Copyright 2001 Wiley-Liss, Inc.

  19. A study of the influence of the sun on optimal two-impulse Earth-to-Moon trajectories with moderate time of flight in the three-body and four-body models

    NASA Astrophysics Data System (ADS)

    Filho, Luiz Arthur Gagg; da Silva Fernandes, Sandro

    2017-05-01

    In this work, a study about the influence of the Sun on optimal two-impulse Earth-to-Moon trajectories for interior transfers with moderate time of flight is presented considering the three-body and the four-body models. The optimization criterion is the total characteristic velocity which represents the fuel consumption of an infinite thrust propulsion system. The optimization problem has been formulated using the classic planar circular restricted three-body problem (PCR3BP) and the planar bi-circular restricted four-body problem (PBR4BP), and, it consists of transferring a spacecraft from a circular low Earth orbit (LEO) to a circular low Moon orbit (LMO) with minimum fuel consumption. The Sequential Gradient Restoration Algorithm (SGRA) is applied to determine the optimal solutions. Numerical results are presented for several final altitudes of a clockwise or a counterclockwise circular low Moon orbit considering a specified altitude of a counterclockwise circular low Earth orbit. Two types of analysis are performed: in the first one, the initial position of the Sun is taken as a parameter and the major parameters describing the optimal trajectories are obtained by solving an optimization problem of one degree of freedom. In the second analysis, an optimization problem with two degrees of freedom is considered and the initial position of the Sun is taken as an additional unknown.

  20. Abrasion of acrylic veneers by simulated toothbrushing.

    PubMed

    Xu, H C; Söremark, R; Wiktorsson, G; Wang, T; Liu, W Y

    1984-12-01

    The abrasion responses were tested on four acrylic veneer materials, K + B Plus, K + B 75, Isosit, and Ivocron. The studies were performed in two independent research laboratories. Two different brushing machines were used with an abrasive slurry. The results were used for comparing the degree of abrasion for the resin materials. Three analytical methods of measuring the degree of abrasive wear were used: surface profile measurement, microscopic evaluation, and measurement of loss of volume. Isosit showed the best abrasion resistance of the four materials tested.

  1. The AGARD tip research agenda for Scientific and Technical Information (STI)

    NASA Technical Reports Server (NTRS)

    Blados, Walter R.

    1992-01-01

    The Research Agenda contains three themes: information management, provision of information, and access to information. Provision of information is further divided into two subordinate themes, dissemination and bibliographic control; access to information is also further divided into two subordinate themes, barriers and equity and networking. Each theme or sub-theme was examined from four possible aspects, namely, human resources, quality assurance, cost, and technology. It was concluded that, in fact, a theme or sub-theme need not contain all four aspects.

  2. NOTE: Do acupuncture points exist?

    NASA Astrophysics Data System (ADS)

    Yan, Xiaohui; Zhang, Xinyi; Liu, Chenglin; Dang, Ruishan; Huang, Yuying; He, Wei; Ding, Guanghong

    2009-05-01

    We used synchrotron x-ray fluorescence analysis to probe the distribution of four chemical elements in and around acupuncture points, two located in the forearm and two in the lower leg. Three of the four acupuncture points showed significantly elevated concentrations of elements Ca, Fe, Cu and Zn in relation to levels in the surrounding tissue, with similar elevation ratios for Cu and Fe. The mapped distribution of these elements implies that each acupuncture point seems to be elliptical with the long axis along the meridian.

  3. Streamlining emergent hand and wrist radiography with a modified four-view protocol.

    PubMed

    Chou, Henry Y; Steenburg, Scott D; Dunkle, Jeffrey W; Gussick, Sean D; Petersen, Matthew J; Kohli, Marc D; Shen, Changyu; Lin, Hongbo

    2016-08-01

    This study aims to determine whether a modified four-view hand and wrist study performs comparably to the traditional seven views in the evaluation of acute hand and wrist fractures. This retrospective study was approved by the institutional review board with waiver of informed consent. Two hundred forty patients (50 % male; ages 18-92 years) with unilateral three-view hand (posteroanterior, oblique, and lateral) and four-view wrist (posteroanterior, oblique, lateral, and ulnar deviation) radiographs obtained concurrently following trauma were included in this study. Four emergency radiologists interpreted the original seven images, with two radiologists independently evaluating each study. The patients' radiographs were then recombined into four-view series using the three hand images and the ulnar deviated wrist image. These were interpreted by the same radiologists following an 8-week delay. Kappa statistics were generated to measure inter-observer and inter-method agreement. Generalized linear mixed model analysis was performed between the seven- and four-view methods. Of the 480 reports generated in each of the seven- and four-view image sets, 142 (29.6 %) of the seven-view and 126 (26.2 %) of the four-view reports conveyed certain or suspected acute osseous findings. Average inter-observer kappa coefficients were 0.7845 and 0.8261 for the seven- and four-view protocols, respectively. The average inter-method kappa was 0.823. The odds ratio of diagnosing injury using the four-view compared to the seven-view algorithm was 0.69 (CI 0.45-1.06, P = 0.0873). The modified four-view hand and wrist radiographic series produces diagnostic results comparable to the traditional seven views for acute fracture evaluation.

  4. Two-dimensional Zn(II) and one-dimensional Co(II) coordination polymers based on benzene-1,4-dicarboxylate and pyridine ligands.

    PubMed

    Zhou, Li-Juan; Han, Chang-Bao; Wang, Yu-Ling

    2016-02-01

    Coordination polymers constructed from metal ions and organic ligands have attracted considerable attention owing to their diverse structural topologies and potential applications. Ligands containing carboxylate groups are among the most extensively studied because of their versatile coordination modes. Reactions of benzene-1,4-dicarboxylic acid (H2BDC) and pyridine (py) with Zn(II) or Co(II) yielded two new coordination polymers, namely, poly[(μ4-benzene-1,4-dicarboxylato-κ(4)O:O':O'':O''')(pyridine-κN)zinc(II)], [Zn(C8H4O2)(C5H5N)]n, (I), and catena-poly[aqua(μ3-benzene-1,4-dicarboxylato-κ(3)O:O':O'')bis(pyridine-κN)cobalt(II)], [Co(C8H4O2)(C5H5N)2(H2O)]n, (II). In compound (I), the Zn(II) cation is five-coordinated by four carboxylate O atoms from four BDC(2-) ligands and one pyridine N atom in a distorted square-pyramidal coordination geometry. Four carboxylate groups bridge two Zn(II) ions to form centrosymmetric paddle-wheel-like Zn2(μ2-COO)4 units, which are linked by the benzene rings of the BDC(2-) ligands to generate a two-dimensional layered structure. The two-dimensional layer is extended into a three-dimensional supramolecular structure with the help of π-π stacking interactions between the aromatic rings. Compound (II) has a one-dimensional double-chain structure based on Co2(μ2-COO)2 units. The Co(II) cations are bridged by BDC(2-) ligands and are octahedrally coordinated by three carboxylate O atoms from three BDC(2-) ligands, one water O atom and two pyridine N atoms. Interchain O-H...O hydrogen-bonding interactions link these chains to form a three-dimensional supramolecular architecture.

  5. Operative treatment of hip fractures in patients receiving hemodialysis.

    PubMed

    Tosun, Bilgehan; Atmaca, Halil; Gok, Umit

    2010-11-01

    Fifteen hips in 13 patients with hip fracture were treated in patients receiving hemodialysis for chronic renal failure. There were four intertrochanteric and 11 femoral neck fractures. 10 of the 11 femoral neck fractures and one of the four intertrochanteric fractures were treated with cemented bipolar hemiarthroplasty. Two intertrochanteric fractures fixed with sliding compression screws. External fixation was used for stabilization in two patients who had femoral neck and intertrochanteric fractures. Two intertrochanteric fractures that were treated with sliding hip screw showed radiological union postoperatively at the 6th month. Of the 11 hemiarthroplasty, four hips developed aseptic loosening (36%). According to Harris hip score grading system, three (37.5%) poor, two (25%) fair, two (25%) good and one (12.5%) case had excellent outcome in the hemiarthroplasty group. The survival of dialysis patients with a hip fracture is markedly reduced. Initial treatment of hemiarthroplasty allows early mobilization and prevents revision surgery.

  6. Add Another Dimension to Your Life: With a Bonus Recipe for Making Tesseracts

    ERIC Educational Resources Information Center

    Chick, Helen

    2007-01-01

    A cube is a solid in three dimensions, with three mutually perpendicular right angles evident at the vertices. In this article, the author describes how to create a four-dimensional cube. Before searching this extra dimension, she first reviews what people know about zero, one, two, and three dimensions, and certain shapes in each of these. She…

  7. English Vocabulary Instruction in Six Early Childhood Classrooms in Hong Kong

    ERIC Educational Resources Information Center

    Lau, Carrie; Rao, Nirmala

    2013-01-01

    Vocabulary instruction during English language learning was observed for one week in six classrooms (three K2 classes for four-year olds and three K3 classes for five-year olds) from three kindergartens in two districts of Hong Kong. From 23 sessions of observations and 535 minutes of data, field notes were coded to identify instances of…

  8. Search for consanguinity within and among families of patients with trichothiodystrophy associated with xeroderma pigmentosum.

    PubMed Central

    Nuzzo, F; Zei, G; Stefanini, M; Colognola, R; Santachiara, A S; Lagomarsini, P; Marinoni, S; Salvaneschi, L

    1990-01-01

    The association of two rare hereditary disorders, trichothiodystrophy (TTD) and xeroderma pigmentosum (XP), was found in four patients from three families, apparently unrelated but living in the same geographical area. In order to test the hypothesis of a common ancestor, consanguinity within and among the families was checked using three different approaches: reconstruction of genealogical trees, typing of blood markers, and surname analysis. The results of the three types of analyses strengthen the hypothesis that, in at least two out of the three families, the genetic defect determining the TTD/XP phenotype is identical by descent, as a consequence of remote inbreeding. This implies that if two mutations are responsible for the two diseases they are at linked loci or affect the same gene. PMID:2308151

  9. A fiber-laser-pumped four-wavelength continuous-wave mid-infrared optical parametric oscillator

    NASA Astrophysics Data System (ADS)

    Wang, Peng; Shang, Yaping; Li, Xiao; Xu, Xiaojun

    2017-10-01

    In this paper, a four-wavelength continuous-wave mid-infrared optical parametric oscillator was demonstrated for the first time. The pump source was a home-built linearly polarized Yb-doped fiber laser and the maximum output power was 72.5 W. The pump source had three central wavelengths locating at 1060 nm, 1065 nm and 1080 nm. Four idler emissions with different wavelengths were generated which were 3132 nm, 3171 nm, 3310 nm and 3349 nm under the maximum pump power. The maximum idler output reached 8.7 W, indicating a 15% pump-to-idler slope efficiency. The signal wave generated in the experiment had two wavelengths which were 1595 nm and 1603 nm under the maximum pump power. It was analyzed that four nonlinear progresses occurred in the experiment, two of them being optical parametric oscillation and the rest two being intracavity difference frequency generation.

  10. The Ostomy: Part One of Two Parts.

    ERIC Educational Resources Information Center

    Watt, Rosemary C.; And Others

    1985-01-01

    Teaches nurses to identify four common indications for fecal diversion surgery: list three types of colostomies; distinguish a colostomy from an ileostomy; describe the two basic methods of colostomy management; and identify factors that influence the choice of method of colostomy care. (CT)

  11. Multilaboratory Validation of First Action Method 2016.04 for Determination of Four Arsenic Species in Fruit Juice by High-Performance Liquid Chromatography-Inductively Coupled Plasma-Mass Spectrometry.

    PubMed

    Kubachka, Kevin; Heitkemper, Douglas T; Conklin, Sean

    2017-07-01

    Before being designated AOAC First Action Official MethodSM 2016.04, the U.S. Food and Drug Administration's method, EAM 4.10 High Performance Liquid Chromatography-Inductively Coupled Plasma-Mass Spectrometric Determination of Four Arsenic Species in Fruit Juice, underwent both a single-laboratory validation and a multilaboratory validation (MLV) study. Three federal and five state regulatory laboratories participated in the MLV study, which is the primary focus of this manuscript. The method was validated for inorganic arsenic (iAs) measured as the sum of the two iAs species arsenite [As(III)] and arsenate [As(V)], dimethylarsinic acid (DMA), and monomethylarsonic acid (MMA) by analyses of 13 juice samples, including three apple juice, three apple juice concentrate, four grape juice, and three pear juice samples. In addition, two water Standard Reference Materials (SRMs) were analyzed. The method LODs and LOQs obtained among the eight laboratories were approximately 0.3 and 2 ng/g, respectively, for each of the analytes and were adequate for the intended purpose of the method. Each laboratory analyzed method blanks, fortified method blanks, reference materials, triplicate portions of each juice sample, and duplicate fortified juice samples (one for each matrix type) at three fortification levels. In general, repeatability and reproducibility of the method was ≤15% RSD for each species present at a concentration >LOQ. The average recovery of fortified analytes for all laboratories ranged from 98 to 104% iAs, DMA, and MMA for all four juice sample matrixes. The average iAs results for SRMs 1640a and 1643e agreed within the range of 96-98% of certified values for total arsenic.

  12. A Typology of Students Based on Academic Entitlement

    ERIC Educational Resources Information Center

    Luckett, Michael; Trocchia, Philip J.; Noel, Noel Mark; Marlin, Dan

    2017-01-01

    Two hundred ninety-three university business students were surveyed using an academic entitlement (AE) scale updated to include new technologies. Using factor analysis, three components of AE were identified: grade entitlement, behavioral entitlement, and service entitlement. A k-means clustering procedure was then applied to identify four groups…

  13. Reliability of Test Scores in Nonparametric Item Response Theory.

    ERIC Educational Resources Information Center

    Sijtsma, Klaas; Molenaar, Ivo W.

    1987-01-01

    Three methods for estimating reliability are studied within the context of nonparametric item response theory. Two were proposed originally by Mokken and a third is developed in this paper. Using a Monte Carlo strategy, these three estimation methods are compared with four "classical" lower bounds to reliability. (Author/JAZ)

  14. Decatur House: A Home of the Rich and Powerful. Teaching with Historic Places.

    ERIC Educational Resources Information Center

    Schuldt, Robin Fogg

    1994-01-01

    Presents a lesson based on Decatur House, the home of Stephen Decatur, a military commander during the war with the Barbary Pirates and the War of 1812. Outlines student objectives and three learning activities. Includes four student readings, one map, three drawings, and two photographs. (CFR)

  15. Cles: Etes-vous bon detective?; Enigmes grammaticales; Problemes policiers; Kidnapping (Keys: Are You a Good Detective?; Grammatical Puzzles; Detective Mysteries; Kidnapping).

    ERIC Educational Resources Information Center

    Debyser, Francis; And Others

    1984-01-01

    Four sets of French classroom activities are presented: a mystery whose clues include two postcard messages; three puzzles with grammar-related clues; a mystery contained in three comic strip frames; and the solving of a kidnapping mystery. (MSE)

  16. Public Speaking Practices: Analysis of Aristotle's "Rhetoric."

    ERIC Educational Resources Information Center

    Markham, Reed

    Aristotle's "Rhetoric" is divided into three books which describe the stages of preparing a public address. Book One establishes the philosophical position of rhetoric to logic. It also establishes four purposes of rhetoric and discusses three types of proof. Aristotle defines rhetoric as a faculty for providing two modes of…

  17. District Response to the Demonstration: The Practice of Technology.

    ERIC Educational Resources Information Center

    Fleming-McCormick, Treseen; And Others

    This paper reports on how technology is currently used in nine schools that educators view as "promising" exemplars of technology use. Four elementary, three middle and two high schools from Arizona, California and Nevada (three schools from each state) were examined. Extensive document review and telephone interviews were conducted in…

  18. Two-loop renormalization of quantum gravity simplified

    DOE PAGES

    Bern, Zvi; Chi, Huan -Hang; Dixon, Lance; ...

    2017-02-22

    The coefficient of the dimensionally regularized two-loop R 3 divergence of (nonsupersymmetric) gravity theories has recently been shown to change when nondynamical three-forms are added to the theory, or when a pseudoscalar is replaced by the antisymmetric two-form field to which it is dual. This phenomenon involves evanescent operators, whose matrix elements vanish in four dimensions, including the Gauss-Bonnet operator which is also connected to the trace anomaly. On the other hand, these effects appear to have no physical consequences for renormalized scattering processes. In particular, the dependence of the two-loop four-graviton scattering amplitude on the renormalization scale is simple.more » As a result, we explain this result for any minimally-coupled massless gravity theory with renormalizable matter interactions by using unitarity cuts in four dimensions and never invoking evanescent operators.« less

  19. Continuum modeling of three-dimensional truss-like space structures

    NASA Technical Reports Server (NTRS)

    Nayfeh, A. H.; Hefzy, M. S.

    1978-01-01

    A mathematical and computational analysis capability has been developed for calculating the effective mechanical properties of three-dimensional periodic truss-like structures. Two models are studied in detail. The first, called the octetruss model, is a three-dimensional extension of a two-dimensional model, and the second is a cubic model. Symmetry considerations are employed as a first step to show that the specific octetruss model has four independent constants and that the cubic model has two. The actual values of these constants are determined by averaging the contributions of each rod element to the overall structure stiffness. The individual rod member contribution to the overall stiffness is obtained by a three-dimensional coordinate transformation. The analysis shows that the effective three-dimensional elastic properties of both models are relatively close to each other.

  20. Clinical findings and effect of sodium hydrogen carbonate in patients with glutathione synthetase deficiency.

    PubMed

    Gündüz, Mehmet; Ünal, Özlem; Kavurt, Sumru; Türk, Emrecan; Mungan, Neslihan Önenli

    2016-04-01

    Glutathione synthetase (GS) deficiency is a rare inborn error of glutathione (GSH) metabolism manifested by severe metabolic acidosis, hemolytic anemia, neurological problems and massive excretion of pyroglutamic acid (5-oxoproline) in the urine. The disorder has mild, moderate, and severe clinical variants. We aimed to report clinical and laboratory findings of four patients, effect of sodium hydrogen carbonate treatment and long-term follow up of three patients. Urine organic acid analysis was performed with gas chromatography-mass spectrometry. Molecular genetic analysis was performed in three patients, mutation was found in two of them. Enzyme analysis was performed in one patient. Clinical and laboratory findings of four patients were evaluated. One patient died at 4 months old, one patient's growth and development are normal, two patients have developed intellectual disability and seizures in the long term follow up period. Three patients benefited from sodium hydrogen carbonate treatment. The clinical picture varies from patient to patient, so it is difficult to predict the prognosis and the effectiveness of treatment protocols. We reported long term follow up of four patients and demonstrated that sodium hydrogen carbonate is effective for treatment of chronic metabolic acidosis in GS deficieny.

  1. The Limited Role of Number of Nested Syntactic Dependencies in Accounting for Processing Cost: Evidence from German Simplex and Complex Verbal Clusters

    PubMed Central

    Bader, Markus

    2018-01-01

    This paper presents three acceptability experiments investigating German verb-final clauses in order to explore possible sources of sentence complexity during human parsing. The point of departure was De Vries et al.'s (2011) generalization that sentences with three or more crossed or nested dependencies are too complex for being processed by the human parsing mechanism without difficulties. This generalization is partially based on findings from Bach et al. (1986) concerning the acceptability of complex verb clusters in German and Dutch. The first experiment tests this generalization by comparing two sentence types: (i) sentences with three nested dependencies within a single clause that contains three verbs in a complex verb cluster; (ii) sentences with four nested dependencies distributed across two embedded clauses, one center-embedded within the other, each containing a two-verb cluster. The results show that sentences with four nested dependencies are judged as acceptable as control sentences with only two nested dependencies, whereas sentences with three nested dependencies are judged as only marginally acceptable. This argues against De Vries et al.'s (2011) claim that the human parser can process no more than two nested dependencies. The results are used to refine the Verb-Cluster Complexity Hypothesis of Bader and Schmid (2009a). The second and the third experiment investigate sentences with four nested dependencies in more detail in order to explore alternative sources of sentence complexity: the number of predicted heads to be held in working memory (storage cost in terms of the Dependency Locality Theory [DLT], Gibson, 2000) and the length of the involved dependencies (integration cost in terms of the DLT). Experiment 2 investigates sentences for which storage cost and integration cost make conflicting predictions. The results show that storage cost outweighs integration cost. Experiment 3 shows that increasing integration cost in sentences with two degrees of center embedding leads to decreased acceptability. Taken together, the results argue in favor of a multifactorial account of the limitations on center embedding in natural languages. PMID:29410633

  2. The Limited Role of Number of Nested Syntactic Dependencies in Accounting for Processing Cost: Evidence from German Simplex and Complex Verbal Clusters.

    PubMed

    Bader, Markus

    2017-01-01

    This paper presents three acceptability experiments investigating German verb-final clauses in order to explore possible sources of sentence complexity during human parsing. The point of departure was De Vries et al.'s (2011) generalization that sentences with three or more crossed or nested dependencies are too complex for being processed by the human parsing mechanism without difficulties. This generalization is partially based on findings from Bach et al. (1986) concerning the acceptability of complex verb clusters in German and Dutch. The first experiment tests this generalization by comparing two sentence types: (i) sentences with three nested dependencies within a single clause that contains three verbs in a complex verb cluster; (ii) sentences with four nested dependencies distributed across two embedded clauses, one center-embedded within the other, each containing a two-verb cluster. The results show that sentences with four nested dependencies are judged as acceptable as control sentences with only two nested dependencies, whereas sentences with three nested dependencies are judged as only marginally acceptable. This argues against De Vries et al.'s (2011) claim that the human parser can process no more than two nested dependencies. The results are used to refine the Verb-Cluster Complexity Hypothesis of Bader and Schmid (2009a). The second and the third experiment investigate sentences with four nested dependencies in more detail in order to explore alternative sources of sentence complexity: the number of predicted heads to be held in working memory (storage cost in terms of the Dependency Locality Theory [DLT], Gibson, 2000) and the length of the involved dependencies (integration cost in terms of the DLT). Experiment 2 investigates sentences for which storage cost and integration cost make conflicting predictions. The results show that storage cost outweighs integration cost. Experiment 3 shows that increasing integration cost in sentences with two degrees of center embedding leads to decreased acceptability. Taken together, the results argue in favor of a multifactorial account of the limitations on center embedding in natural languages.

  3. Single phase four pole/six pole motor

    DOEpatents

    Kirschbaum, H.S.

    1984-10-09

    A single phase alternating current electric motor is provided with a main stator winding having two coil groups each including the series connection of three coils. These coil groups can be connected in series for six pole operation and in parallel for four pole operation. The coils are approximately equally spaced around the periphery of the machine but are not of equal numbers of turns. The two coil groups are identically wound and spaced 180 mechanical degrees apart. One coil of each group has more turns and a greater span than the other two coils. 10 figs.

  4. Virtual Mirrors

    ERIC Educational Resources Information Center

    Greenslade, Thomas B., Jr.

    2010-01-01

    The multiple-reflection photograph in Fig. 1 was taken in an elevator on board the cruise ship Norwegian Jade in March 2008. Three of the four walls of the elevator were mirrored, allowing me to see the combination of two standard arrangements of plane mirrors: two mirrors set at 90 degrees to each other and two parallel mirrors. Optical phenomena…

  5. Durable antibody responses following one dose of the bivalent human papillomavirus L1 virus-like particle vaccine in the Costa Rica Vaccine Trial.

    PubMed

    Safaeian, Mahboobeh; Porras, Carolina; Pan, Yuanji; Kreimer, Aimee; Schiller, John T; Gonzalez, Paula; Lowy, Douglas R; Wacholder, Sholom; Schiffman, Mark; Rodriguez, Ana C; Herrero, Rolando; Kemp, Troy; Shelton, Gloriana; Quint, Wim; van Doorn, Leen-Jan; Hildesheim, Allan; Pinto, Ligia A

    2013-11-01

    The Costa Rica HPV16/18 Vaccine Trial (CVT) showed that four-year vaccine efficacy against 12-month HPV16/18 persistent infection was similarly high among women who received one, two, or the recommended three doses of the bivalent HPV16/18 L1 virus-like particle (VLP) vaccine. Live-attenuated viral vaccines, but not simple-subunit vaccines, usually induce durable lifelong antibody responses after a single dose. It is unclear whether noninfectious VLP vaccines behave more like live-virus or simple-subunit vaccines in this regard. To explore the likelihood that efficacy will persist longer term, we investigated the magnitude and durability of antibodies to this vaccine by measuring HPV16- and HPV18-specific antibodies by VLP-ELISA using serum from enrollment, vaccination, and annual visits through four years in four vaccinated groups; one-dose (n = 78), two-doses separated by one month (n = 140), two doses separated by six months (n = 52), and three scheduled doses (n = 120, randomly selected). We also tested enrollment sera from n = 113 HPV16- or HPV18 L1-seropositive women prevaccination, presumably from natural infection. At four years, 100% of women in all groups remained HPV16/18 seropositive; both HPV16/18 geometric mean titers (GMT) among the extended two-dose group were non-inferior to the three-dose group, and ELISA titers were highly correlated with neutralization titers in all groups. Compared with the natural infection group, HPV16/18 GMTs were, respectively, at least 24 and 14 times higher among the two-dose and 9 and 5 times higher among one-dose vaccinees. Antibody levels following one-dose remained stable from month 6 through month 48. Results raise the possibility that even a single dose of HPV VLPs will induce long-term protection. ©2013 AACR.

  6. Dengue virus in Mexican bats.

    PubMed

    Aguilar-Setién, A; Romero-Almaraz, M L; Sánchez-Hernández, C; Figueroa, R; Juárez-Palma, L P; García-Flores, M M; Vázquez-Salinas, C; Salas-Rojas, M; Hidalgo-Martínez, A C; Pierlé, S Aguilar; García-Estrada, C; Ramos, C

    2008-12-01

    Individuals belonging to five families, 12 genera, and 19 different species of bats from dengue endemic areas in the Gulf and Pacific coasts of Mexico were examined by ELISA, RT-PCR, and for the presence of dengue virus (DV) NS1 protein. Nine individuals from four species were seropositive by ELISA: three insectivorous, Myotis nigricans (four positives/12 examined), Pteronotus parnellii (3/19), and Natalus stramineus (1/4), and one frugivorous Artibeus jamaicensis (1/35) (12.86% seroprevalence in positive species). DV serotype 2 was detected by RT-PCR in four samples from three species (all from the Gulf coast - rainy season): two frugivorous, A. jamaicensis (2/9), and Carollia brevicauda (1/2), and one insectivorous, M. nigricans (1/11). The latter was simultaneously positive for NS1 protein. DV RT-PCR positive animals were all antibody seronegative. M. nigricans showed positive individuals for all three tests. This is the first evidence suggesting the presence of DV in bats from Mexico.

  7. A Clifford algebra approach to chiral symmetry breaking and fermion mass hierarchies

    NASA Astrophysics Data System (ADS)

    Lu, Wei

    2017-09-01

    We propose a Clifford algebra approach to chiral symmetry breaking and fermion mass hierarchies in the context of composite Higgs bosons. Standard model fermions are represented by algebraic spinors of six-dimensional binary Clifford algebra, while ternary Clifford algebra-related flavor projection operators control allowable flavor-mixing interactions. There are three composite electroweak Higgs bosons resulted from top quark, tau neutrino, and tau lepton condensations. Each of the three condensations gives rise to masses of four different fermions. The fermion mass hierarchies within these three groups are determined by four-fermion condensations, which break two global chiral symmetries. The four-fermion condensations induce axion-like pseudo-Nambu-Goldstone bosons and can be dark matter candidates. In addition to the 125 GeV Higgs boson observed at the Large Hadron Collider, we anticipate detection of tau neutrino composite Higgs boson via the charm quark decay channel.

  8. Pediatric Lassa fever: a review of 33 Liberian cases.

    PubMed

    Monson, M H; Cole, A K; Frame, J D; Serwint, J R; Alexander, S; Jahrling, P B

    1987-03-01

    Thirty-three cases of pediatric Lassa fever were identified at Curran Lutheran Hospital and Phebe Hospital in Liberia between January 1980 and March 1984. All 18 fetal cases died and the case-fatality rate for 15 childhood cases was 27%. We identified four clinical presentations according to age, including a case of congenital Lassa fever, a condition not reported previously. Two cases of Lassa fever were found serologically during a one-month survey of all pediatric admissions at Curran Lutheran Hospital, 2.4% of those children who had serum pairs collected. We also identified a "swollen baby syndrome" consisting of widespread edema, abdominal distention, and bleeding. This distinctive clinical presentation of Lassa fever ended in death in three of four cases and was present in three of the four childhood deaths in this series. Its absence seems to be a good prognostic indicator in children.

  9. Minimizing the Sum of Completion Times with Resource Dependant Times

    NASA Astrophysics Data System (ADS)

    Yedidsion, Liron; Shabtay, Dvir; Kaspi, Moshe

    2008-10-01

    We extend the classical minimization sum of completion times problem to the case where the processing times are controllable by allocating a nonrenewable resource. The quality of a solution is measured by two different criteria. The first criterion is the sum of completion times and the second is the total weighted resource consumption. We consider four different problem variations for treating the two criteria. We prove that this problem is NP-hard for three of the four variations even if all resource consumption weights are equal. However, somewhat surprisingly, the variation of minimizing the integrated objective function is solvable in polynomial time. Although the sum of completion times is arguably the most important scheduling criteria, the complexity of this problem, up to this paper, was an open question for three of the four variations. The results of this research have various implementations, including efficient battery usage on mobile devices such as mobile computer, phones and GPS devices in order to prolong their battery duration.

  10. Exploration of the factor structure of the Kirton Adaption-Innovation Inventory using bootstrapping estimation.

    PubMed

    Im, Subin; Min, Soonhong

    2013-04-01

    Exploratory factor analyses of the Kirton Adaption-Innovation Inventory (KAI), which serves to measure individual cognitive styles, generally indicate three factors: sufficiency of originality, efficiency, and rule/group conformity. In contrast, a 2005 study by Im and Hu using confirmatory factor analysis supported a four-factor structure, dividing the sufficiency of originality dimension into two subdimensions, idea generation and preference for change. This study extends Im and Hu's (2005) study of a derived version of the KAI by providing additional evidence of the four-factor structure. Specifically, the authors test the robustness of the parameter estimates to the violation of normality assumptions in the sample using bootstrap methods. A bias-corrected confidence interval bootstrapping procedure conducted among a sample of 356 participants--members of the Arkansas Household Research Panel, with middle SES and average age of 55.6 yr. (SD = 13.9)--showed that the four-factor model with two subdimensions of sufficiency of originality fits the data significantly better than the three-factor model in non-normality conditions.

  11. BACTERIAL MENINGITIS AND OTHER DISEASES AFFECTING THE MENINGES—A Review of 349 Cases

    PubMed Central

    Cover, William L.

    1949-01-01

    Three hundred and forty-nine cases of disease affecting the meninges were observed at the San Bernardino County Charity Hospital in an eight year period. A total of 29 patients with meningococcal, H. influenzae and pneumococcal meningitis were treated. There were four deaths, of which three occurred during the first 24 hours in the hospital. Of 22 cases of unclassified meningitis, four probably were tuberculous, four probably were meningococcal and two probably were of virus origin. Under present treatment programs the differentiation between viral and bacterial meningitides is difficult and it is possible, therefore, that the reported incidence of the two groups may not represent the facts. Of 22 cases of unclassified meningitis, 12 had no specific characteristics which would permit a clinical diagnosis. One of the patients died. Of 70 cases of clinical meningitis, the infecting organism was identified in 69 per cent. Meningococcal meningitis made up only 17 per cent of 70 cases of purulent meningitis observed between July 1, 1945, and July 1, 1948. PMID:18137216

  12. Effect of Attachment Type on Denture Strain in Maxillary Implant Overdentures: Part 1. Overdenture with Palate.

    PubMed

    Takahashi, Toshihito; Gonda, Tomoya; Maeda, Yoshinobu

    This study examined the effects of attachments on strain in maxillary implant overdentures supported by two or four implants. A maxillary edentulous model with implants inserted into anterior, premolar, and molar areas was fabricated, and three types of unsplinted attachments-ball, locator, and magnet-were set on the implants distributed under various conditions. Maxillary experimental dentures were fabricated, and two strain gauges were attached at the anterior midline on the labial and palatal sides. A vertical occlusal load of 98 N was applied and shear strain of the dentures was measured. On both sides, magnet attachments resulted in the lowest shear strain, while ball attachments resulted in the highest shear strain under most conditions. However, differences in shear strain among the three attachment types were not significant when supported by four implants, especially molar implants. Shear strain of the maxillary implant overdenture was lowest when using magnet attachments. Magnet attachments mounted on four implants are recommended to prevent denture complications when using maxillary implant overdentures.

  13. Four-body interaction energy for compressed solid krypton from quantum theory.

    PubMed

    Tian, Chunling; Wu, Na; Liu, Fusheng; Saxena, Surendra K; Zheng, Xingrong

    2012-07-28

    The importance of the four-body contribution in compressed solid krypton was first evaluated using the many-body expansion method and the coupled cluster theory with full single and double excitations plus perturbative treatment of triples. All different four-atom clusters existing in the first- and second-nearest neighbor shells of face-centered cubic krypton were considered, and both self-consistent-field Hartree-Fock and correlation parts of the four-body interaction were accurately determined from the ambient conditions up to eightfold volume compression. We find that the four-body interaction energy is negative at compression ratio lower than 2, where the dispersive forces play a dominant role. With increasing the compression, the four-body contribution becomes repulsive and significantly cancels the over-softening effects of the three-body potential. The obtained equation of state (EOS) was compared with the experiments and the density-functional theory calculations. It shows that combination of the four-body effects with two- and three-body interactions leads to an excellent agreement with EOS measurements throughout the whole experimental range 0-130 GPa, and extends the prediction to 300 GPa.

  14. Generation of a composite grid for turbine flows and consideration of a numerical scheme

    NASA Technical Reports Server (NTRS)

    Choo, Y.; Yoon, S.; Reno, C.

    1986-01-01

    A composite grid was generated for flows in turbines. It consisted of the C-grid (or O-grid) in the immediate vicinity of the blade and the H-grid in the middle of the blade passage between the C-grids and in the upstream region. This new composite grid provides better smoothness, resolution, and orthogonality than any single grid for a typical turbine blade with a large camber and rounded leading and trailing edges. The C-H (or O-H) composite grid has an unusual grid point that is connected to more than four neighboring nodes in two dimensions (more than six neighboring nodes in three dimensions). A finite-volume lower-upper (LU) implicit scheme to be used on this grid poses no problem and requires no special treatment because each interior cell of this composite grid has only four neighboring cells in two dimensions (six cells in three dimensions). The LU implicit scheme was demonstrated to be efficient and robust for external flows in a broad flow regime and can be easily applied to internal flows and extended from two to three dimensions.

  15. International Symposium On the Ecological Effects of Arctic Airborne Contaminants, held in Reykjavik, Iceland on October 4 - 8, 1993. Abstracts

    DTIC Science & Technology

    1993-10-08

    fluctuations occur, there appears to be a general increase in concentration of the lighter congener groups (two, three, and four chlorines) toward the...traditional diet in communities across the NWT. Caribou were collected from four herds in the first year of a study to examine levels of organo- chlorine...organochlorine pesticides, and PCBs. Results of variability studies comparing concentrations of target analytes in four species (Cetraria cucullata

  16. Invasion percolation between two sites in two, three, and four dimensions

    NASA Astrophysics Data System (ADS)

    Lee, Sang Bub

    2009-06-01

    The mass distribution of invaded clusters in non-trapping invasion percolation between an injection site and an extraction site has been studied, in two, three, and four dimensions. This study is an extension of the recent study focused on two dimensions by Araújo et al. [A.D. Araújo, T.F. Vasconcelos, A.A. Moreira, L.S. Lucena, J.S. Andrade Jr., Phys. Rev. E 72 (2005) 041404] with respect to higher dimensions. The mass distribution exhibits a power-law behavior, P(m)∝m. It has been found that the index α for pe

  17. Assessing the content, presentation, and readability of dental informed consents.

    PubMed

    Glick, Aaron; Taylor, David; Valenza, John A; Walji, Muhammad F

    2010-08-01

    Informed consents are important aids in helping patients make optimal decisions. Little knowledge exists about the quality of dental informed consents. Fifty-two informed consents used throughout the University of Texas Health Science Center at Houston Dental Branch were evaluated based on the quality of their content, readability, and presentation. Content quality was judged on four basic elements: description of procedure, risk, benefits, and alternatives. Of the clinical consents, 26 percent of forms contained all four of the basic content elements, 48 percent contained three of four elements, 16 percent contained two of four elements, and 10 percent contained one of four elements. Presentation quality was judged on twelve criteria items. The average clinical consent included seven out of twelve presentation items, and the average nonclinical consent included eight out of twelve items. Readability was judged using three standard instruments for rating readability: Flesch Reading Ease, Flesch-Kincaid Grade-Level, and Simple Measure of Gobbledygook (SMOG) grading. Average Flesch-Kincaid Grade-Level was 12.7 (range, 7.4 to 19.1), significantly higher than the recommended ninth grade level (p<.001). The results suggest that many existing dental informed consents may be improved by 1) increasing the comprehensiveness of the content, 2) improving the design and layout, and 3) reducing the readability levels for patient comprehension.

  18. Some finite terms from ladder diagrams in three and four loop maximal supergravity

    NASA Astrophysics Data System (ADS)

    Basu, Anirban

    2015-10-01

    We consider the finite part of the leading local interactions in the low energy expansion of the four graviton amplitude from the ladder skeleton diagrams in maximal supergravity on T 2, at three and four loops. At three loops, we express the {D}8{{R}}4 and {D}10{{R}}4 amplitudes as integrals over the moduli space of an underlying auxiliary geometry. These amplitudes are evaluated exactly for special values of the the moduli of the auxiliary geometry, where the integrand simplifies. We also perform a similar analysis for the {D}8{{R}}4 amplitude at four loops that arise from the ladder skeleton diagrams for a special value of a parameter in the moduli space of the auxiliary geometry. While the dependence of the amplitudes on the volume of the T 2 is very simple, the dependence on the complex structure of the T 2 is quite intricate. In some of the cases, the amplitude consists of terms each of which factorizes into a product of two {SL}(2,{{Z}}) invariant modular forms. While one of the factors is a non-holomorphic Eisenstein series, the other factor splits into a sum of modular forms each of which satisfies a Poisson equation on moduli space with source terms that are bilinear in the Eisenstein series. This leads to several possible perturbative contributions unto genus 5 in type II string theory on S1. Unlike the one and two loop supergravity analysis, these amplitudes also receive non-perturbative contributions from bound states of three D-(anti)instantons in the IIB theory.

  19. A comparative analysis of massed vs. distributed practice on basic math fact fluency growth rates.

    PubMed

    Schutte, Greg M; Duhon, Gary J; Solomon, Benjamin G; Poncy, Brian C; Moore, Kathryn; Story, Bailey

    2015-04-01

    To best remediate academic deficiencies, educators need to not only identify empirically validated interventions but also be able to apply instructional modifications that result in more efficient student learning. The current study compared the effect of massed and distributed practice with an explicit timing intervention to evaluate the extent to which these modifications lead to increased math fact fluency on basic addition problems. Forty-eight third-grade students were placed into one of three groups with each of the groups completing four 1-min math explicit timing procedures each day across 19 days. Group one completed all four 1-min timings consecutively; group two completed two back-to-back 1-min timings in the morning and two back-to-back 1-min timings in the afternoon, and group three completed one, 1-min independent timing four times distributed across the day. Growth curve modeling was used to examine the progress throughout the course of the study. Results suggested that students in the distributed practice conditions, both four times per day and two times per day, showed significantly higher fluency growth rates than those practicing only once per day in a massed format. These results indicate that combining distributed practice with explicit timing procedures is a useful modification that enhances student learning without the addition of extra instructional time when targeting math fact fluency. Copyright © 2015 Society for the Study of School Psychology. Published by Elsevier Ltd. All rights reserved.

  20. A two-class self-paced BCI to control a robot in four directions.

    PubMed

    Ron-Angevin, Ricardo; Velasco-Alvarez, Francisco; Sancha-Ros, Salvador; da Silva-Sauer, Leandro

    2011-01-01

    In this work, an electroencephalographic analysis-based, self-paced (asynchronous) brain-computer interface (BCI) is proposed to control a mobile robot using four different navigation commands: turn right, turn left, move forward and move back. In order to reduce the probability of misclassification, the BCI is to be controlled with only two mental tasks (relaxed state versus imagination of right hand movements), using an audio-cued interface. Four healthy subjects participated in the experiment. After two sessions controlling a simulated robot in a virtual environment (which allowed the user to become familiar with the interface), three subjects successfully moved the robot in a real environment. The obtained results show that the proposed interface enables control over the robot, even for subjects with low BCI performance. © 2011 IEEE

  1. Calibration of Passive Microwave Polarimeters that Use Hybrid Coupler-Based Correlators

    NASA Technical Reports Server (NTRS)

    Piepmeier, J. R.

    2003-01-01

    Four calibration algorithms are studied for microwave polarimeters that use hybrid coupler-based correlators: 1) conventional two-look of hot and cold sources, 2) three looks of hot and cold source combinations, 3) two-look with correlated source, and 4) four-look combining methods 2 and 3. The systematic errors are found to depend on the polarimeter component parameters and accuracy of calibration noise temperatures. A case study radiometer in four different remote sensing scenarios was considered in light of these results. Applications for Ocean surface salinity, Ocean surface winds, and soil moisture were found to be sensitive to different systematic errors. Finally, a standard uncertainty analysis was performed on the four-look calibration algorithm, which was found to be most sensitive to the correlated calibration source.

  2. Flight Crew Workload Evaluation Based on the Workload Function Distribution Method.

    PubMed

    Zheng, Yiyuan; Lu, Yanyu; Jie, Yuwen; Fu, Shan

    2017-05-01

    The minimum flight crew on the flight deck should be established according to the workload for individual crewmembers. Typical workload measures consist of three types: subjective rating scale, task performance, and psychophysiological measures. However, all these measures have their own limitations. To reflect flight crew workload more specifically and comprehensively within the flight environment, and more directly comply with airworthiness regulations, the Workload Function Distribution Method, which combined the basic six workload functions, was proposed. The analysis was based on the different conditions of workload function numbers. Each condition was analyzed from two aspects, which were overall proportion and effective proportion. Three types of approach tasks were used in this study and the NASA-TLX scale was implemented for comparison. Neither the one-function condition nor the two-function condition had the same results with NASA-TLX. However, both the three-function and the four- to six- function conditions were identical with NASA-TLX. Further, the significant differences were different on four to six conditions. The overall proportion was insignificant, while the effective proportions were significant. The results show that the conditions with one function and two functions seemed to have no influence on workload, while executing three functions and four to six functions had an impact on workload. Besides, effective proportions of workload functions were more precisely compared with the overall proportions to indicate workload, especially in the conditions with multiple functions.Zheng Y, Lu Y, Jie Y, Fu S. Flight crew workload evaluation based on the workload function distribution method. Aerosp Med Hum Perform. 2017; 88(5):481-486.

  3. Effect of C-G (Hithiol capsule) on radiotoxemia (in Japanese)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huruta, A.; Nakada, J.

    1973-03-01

    C-G capsule was administered to the patients treated with a large quantity of remote cobalt irradiation, and its effect on symptoms of radiotoxemia was examined. One capsule of C-G containing 80 mg of cysteine and 120 mg of glucose within one capsule were administered three times a day and one capsule out of three was administered between meals. Symptoms of radiotoxemia such as total fatigue, nausea and vomiting, and anorexia were observed. Blood examination was carried out before irradiation, and after irradiation it was carried out once a week. The reported cases consist of 10 cases of breast cancer andmore » its metastasis, four of brain neoplasms, three of penis neoplasms, two of uterus cancer (cervical uterus), two of larynx cancer, and one case each of maxilla cancer, tonsil cancer, parotid gland cancer, lung cancer, ovarian tumor, malignant lympadenoma, and chondrosarcoma. Six control subjects were used. Out of 28 cases, a dramatic response of the patients was recognized in five cases, an effective response in 19 cases, and an ineffective response in four cases. Two cases out of five that were treated with other preventives against radiotoxemia showed an ineffective response, and three cases showed effects thought to be potentiation. Especially, decrease of leukocytes was mild with prompt recovery. In the case of the chest and abdomen irradiation, four control subjects showed strong general radiotoxemia and marked decrease of leukocytes, and in the group administered C-G, one case discontinued irradiation. Moreover, symptoms, radiotherapy, radiotoxemia, and blood findings of the group administered C-G were also explained. (JA)« less

  4. Polysomnographic Technology

    MedlinePlus

    ... a center, but most of the polysomnographic technologists’ work is done at night. Typical shifts are three to four ten to twelve hour shifts per week. The recommended workload is two patients per night. ...

  5. Dynamic analysis, circuit implementation and passive control of a novel four-dimensional chaotic system with multiscroll attractor and multiple coexisting attractors

    NASA Astrophysics Data System (ADS)

    Lai, Bang-Cheng; He, Jian-Jun

    2018-03-01

    In this paper, we construct a novel 4D autonomous chaotic system with four cross-product nonlinear terms and five equilibria. The multiple coexisting attractors and the multiscroll attractor of the system are numerically investigated. Research results show that the system has various types of multiple attractors, including three strange attractors with a limit cycle, three limit cycles, two strange attractors with a pair of limit cycles, two coexisting strange attractors. By using the passive control theory, a controller is designed for controlling the chaos of the system. Both analytical and numerical studies verify that the designed controller can suppress chaotic motion and stabilise the system at the origin. Moreover, an electronic circuit is presented for implementing the chaotic system.

  6. Solar hot water system installed at Quality Inn, Key West, Florida

    NASA Astrophysics Data System (ADS)

    1980-04-01

    The solar energy hot water system installed in the Quality Inn, Key West, Florida, which consists of four buildings is described. Three buildings are low-rise, two-story buildings containing 100 rooms. The fourth is a four-story building with 48 rooms. The solar system was designed to provide approximately 50 percent of the energy required for the domestic hot water system. The solar system consists of approximately 1400 square feet of flat plate collector, two 500 gallon storage tanks, a circulating pump, and a controller. Operation of the system was begun in April 1978, and has continued to date with only three minor interruptions for pump repair. In the first year of operation, it was determined that the use of the solar facility resulted in forty percent fuel savings.

  7. Solar hot water system installed at Quality Inn, Key West, Florida

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The solar energy hot water system installed in the Quality Inn, Key West, Florida, which consists of four buildings is described. Three buildings are low-rise, two-story buildings containing 100 rooms. The fourth is a four-story building with 48 rooms. The solar system was designed to provide approximately 50 percent of the energy required for the domestic hot water system. The solar system consists of approximately 1400 square feet of flat plate collector, two 500 gallon storage tanks, a circulating pump, and a controller. Operation of the system was begun in April 1978, and has continued to date with only three minor interruptions for pump repair. In the first year of operation, it was determined that the use of the solar facility resulted in forty percent fuel savings.

  8. An Analysis of Digital Inclusion Projects: Three Crucial Factors and Four Key Components

    ERIC Educational Resources Information Center

    Smith, Chris

    2015-01-01

    This paper provides an in-depth analysis into two case studies aimed at addressing the digital divide in two developing countries. A detailed description is provided for each case study along with an analysis of how successful the two projects were at addressing the digital divide in Siyabuswa, South Africa and Ennis, Ireland. The two case studies…

  9. Transferability and within- and between-laboratory reproducibilities of EpiSensA for predicting skin sensitization potential in vitro: A ring study in three laboratories.

    PubMed

    Mizumachi, Hideyuki; Sakuma, Megumi; Ikezumi, Mayu; Saito, Kazutoshi; Takeyoshi, Midori; Imai, Noriyasu; Okutomi, Hiroko; Umetsu, Asami; Motohashi, Hiroko; Watanabe, Mika; Miyazawa, Masaaki

    2018-05-03

    The epidermal sensitization assay (EpiSensA) is an in vitro skin sensitization test method based on gene expression of four markers related to the induction of skin sensitization; the assay uses commercially available reconstructed human epidermis. EpiSensA has exhibited an accuracy of 90% for 72 chemicals, including lipophilic chemicals and pre-/pro-haptens, when compared with the results of the murine local lymph node assay. In this work, a ring study was performed by one lead and two naive laboratories to evaluate the transferability, as well as within- and between-laboratory reproducibilities, of EpiSensA. Three non-coded chemicals (two lipophilic sensitizers and one non-sensitizer) were tested for the assessment of transferability and 10 coded chemicals (seven sensitizers and three non-sensitizers, including four lipophilic chemicals) were tested for the assessment of reproducibility. In the transferability phase, the non-coded chemicals (two sensitizers and one non-sensitizer) were correctly classified at the two naive laboratories, indicating that the EpiSensA protocol was transferred successfully. For the within-laboratory reproducibility, the data generated with three coded chemicals tested in three independent experiments in each laboratory gave consistent predictions within laboratories. For the between-laboratory reproducibility, 9 of the 10 coded chemicals tested once in each laboratory provided consistent predictions among the three laboratories. These results suggested that EpiSensA has good transferability, as well as within- and between-laboratory reproducibility. Copyright © 2018 John Wiley & Sons, Ltd.

  10. An in vitro investigation into retention strength and fatigue resistance of various designs of tooth/implant supported overdentures.

    PubMed

    Fatalla, Abdalbseet A; Song, Ke; Du, Tianfeng; Cao, Yingguang

    2012-02-01

    Previously, the choice of prosthetic implant-retained overdentures has depended on data from previous studies about the retention-fatigue strength of the attachment system selected. Little or no data have been available on the correlation between the attachment system selected and the overdenture support configuration. The purpose of the present study was to evaluate the retention force and fatigue resistance of three attachment systems and four support designs of overdenture prosthesis. Four lower edentulous acrylic models were prepared and eight combinations of attachments groups were investigated in the study. These included: O-Rings with mini-dental implants (MDIs), Dalbo elliptic with Dalbo Rotex and fabricated flexible acrylic attachments with both MDI and Dalbo Rotex. The study was divided into four test groups: groups A and B, controls, and groups C and D, experimental groups. Control group A contained three overdenture supports: two free standing MDIs in the canine region and at the midline, and one simulated tooth root with Dalbo Rotex screwed in. Control group B contained four overdenture support foundations: two free standing MDIs in the right canine region and the first premolar region, and two simulated tooth roots with Dalbo Rotex screwed in at the same MDI position, but on the left side of the model. Experimental group C contained three overdenture support foundations: two free standing MDIs in the canine region and at the midline, and one simulated tooth root with MDI screwed in. Experimental group D contained four overdenture support foundations: two free standing MDIs in the right canine region and the first premolar region, and two simulated tooth roots with MDIs screwed in at the same MDI position, but on the left side of the model. Each group was further divided into two subgroups according to attachment type used. Five samples were prepared for each group. Retention force (N) values were recorded initially (0 cycles) and after 360, 720, 1440 and 2880 insertion and removal cycles. During the tensile test a cross-head speed of 10 mm/min was applied. Values of absolute force (AF) and relative force (RF) were statistically analyzed by two-way ANOVA and multiple comparison Tukey's tests between groups and cycles periods. The results of fatigue tests showed a 50% reduction in retention force in the subgroups with flexible attachments. A triangular design of overdenture support foundations with O-Ring attachments revealed the lowest value of AF and a relatively high reduction in RF. The four overdenture support designs with flexible acrylic attachments improved the retention force and reduced the fatigue retention. Furthermore, the results of the investigation demonstrate that flexible acrylic attachments for both teeth and implant-supported overdentures offer a wide range of retention forces.

  11. Fault Detection and Correction for the Solar Dynamics Observatory Attitude Control System

    NASA Technical Reports Server (NTRS)

    Starin, Scott R.; Vess, Melissa F.; Kenney, Thomas M.; Maldonado, Manuel D.; Morgenstern, Wendy M.

    2007-01-01

    The Solar Dynamics Observatory is an Explorer-class mission that will launch in early 2009. The spacecraft will operate in a geosynchronous orbit, sending data 24 hours a day to a devoted ground station in White Sands, New Mexico. It will carry a suite of instruments designed to observe the Sun in multiple wavelengths at unprecedented resolution. The Atmospheric Imaging Assembly includes four telescopes with focal plane CCDs that can image the full solar disk in four different visible wavelengths. The Extreme-ultraviolet Variability Experiment will collect time-correlated data on the activity of the Sun's corona. The Helioseismic and Magnetic Imager will enable study of pressure waves moving through the body of the Sun. The attitude control system on Solar Dynamics Observatory is responsible for four main phases of activity. The physical safety of the spacecraft after separation must be guaranteed. Fine attitude determination and control must be sufficient for instrument calibration maneuvers. The mission science mode requires 2-arcsecond control according to error signals provided by guide telescopes on the Atmospheric Imaging Assembly, one of the three instruments to be carried. Lastly, accurate execution of linear and angular momentum changes to the spacecraft must be provided for momentum management and orbit maintenance. In thsp aper, single-fault tolerant fault detection and correction of the Solar Dynamics Observatory attitude control system is described. The attitude control hardware suite for the mission is catalogued, with special attention to redundancy at the hardware level. Four reaction wheels are used where any three are satisfactory. Four pairs of redundant thrusters are employed for orbit change maneuvers and momentum management. Three two-axis gyroscopes provide full redundancy for rate sensing. A digital Sun sensor and two autonomous star trackers provide two-out-of-three redundancy for fine attitude determination. The use of software to maximize chances of recovery from any hardware or software fault is detailed. A generic fault detection and correction software structure is used, allowing additions, deletions, and adjustments to fault detection and correction rules. This software structure is fed by in-line fault tests that are also able to take appropriate actions to avoid corruption of the data stream.

  12. History of Higher Education Annual, 1988.

    ERIC Educational Resources Information Center

    History of Higher Education Annual, 1988

    1988-01-01

    Four articles and two review papers are presented on themes relating to educational leadership within institutions, organizations, and networks and to the development and promulgation of ideas within academic disciplines. Three of the articles explore the opportunity structures that promoted the rise of two college presidents and one powerful…

  13. Experimental multilocation remote state preparation

    NASA Astrophysics Data System (ADS)

    Rådmark, Magnus; Wieśniak, Marcin; Żukowski, Marek; Bourennane, Mohamed

    2013-09-01

    Transmission of quantum states is a central task in quantum information science. Remote state preparation (RSP) has the same goal as teleportation, i.e., transferring quantum information without sending physically the information carrier, but in RSP the sender knows the state which is to be transmitted. We present experimental demonstrations of RSP for two and three locations. In our experimental scheme Alice (the preparer) and her three partners share four and six photon polarization entangled singlets. This allows us to perform RSP of two or three copies of a single-qubit state, a two-qubit Bell state, and a three-qubit W, or W¯ state. A possibility to prepare two-qubit nonmaximally entangled and GHZ states is also discussed. The ability to remotely prepare an entangled states by local projections at Alice is a distinguishing feature of our scheme.

  14. Noise squeezing of fields that bichromatically excite atoms in a cavity.

    PubMed

    Li, Lingchao; Hu, Xiangming; Rao, Shi; Xu, Jun

    2016-11-14

    It is well known that bichromatic excitation on one common transition can tune the emission or absorption spectra of atoms due to the modulation frequency dependent non-linearities. However little attention has been focused on the quantum dynamics of fields under bichromatic excitation. Here we present dissipative effects on noise correlations of fields in bichromatic interactions with atoms in cavities. We first consider an ensemble of two-level atoms that interacts with the two cavity fields of different frequencies and considerable amplitudes. By transferring the atom-field nonlinearities to the dressed atoms we separate out the dissipative interactions of Bogoliubov modes with the dressed atoms. The Bogoliubov mode dissipation establishes stable two-photon processes of two involved fields and therefore leads to two-mode squeezing. As a generalization, we then consider an ensemble of three-level Λ atoms for cascade bichromatic interactions. We extract the Bogoliubov-like four-mode interactions, which establish a quadrilateral of the two-photon processes of four involved fields and thus result in four-mode squeezing.

  15. CMOS-array design-automation techniques

    NASA Technical Reports Server (NTRS)

    Feller, A.; Lombardt, T.

    1979-01-01

    Thirty four page report discusses design of 4,096-bit complementary metal oxide semiconductor (CMOS) read-only memory (ROM). CMOSROM is either mask or laser programable. Report is divided into six sections; section one describes background of ROM chips; section two presents design goals for chip; section three discusses chip implementation and chip statistics; conclusions and recommendations are given in sections four thru six.

  16. An Analysis of Adult-Child Interaction Patterns in Three-Generational Black Families.

    ERIC Educational Resources Information Center

    Wilson, Melvin N.; Tolson, Timothy F. J.

    This report describes results of contingency-table analyses conducted on four types of black families. Eight families from a sample of 30 families who had been filmed on four occasions during evening meals are discussed as case studies. Two families chosen from each cell of a 2 x 2 factorial design consisting of family structure (one versus two…

  17. Comparisons between Paternal and Maternal Involvement with Sons: Early to Middle Childhood

    ERIC Educational Resources Information Center

    Keown, Louise J.; Palmer, Melanie

    2014-01-01

    This study compared father-son and mother-son involvement in two-parent families from early to middle childhood. Ninety-four families were recruited for a three-year follow-up study that began when the children were four years old. At each time point, in comparison to mothers, fathers were less accessible to their son on weekdays, and spent more…

  18. Restaurant Industry. Grade Three. One in a Series of Career Development Curriculum Units for the Elementary Classroom. (Third Edition).

    ERIC Educational Resources Information Center

    Briggs, Gail; And Others

    Focusing on the occupational clusters of health, hospitality and recreation, this unit entitled "Restaurant Industry" is one of four grade 3 units which are part of a total set of twenty-seven career development curriculum units for grades K-6. This unit is organized into four sections. Section 1 identifies two career…

  19. Adolescence Education: Physical Aspect, Module One; Social Aspects, Module Two; Sex Roles, Module Three; Sexually Transmitted Diseases, Module Four.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific and Cultural Organization, Bangkok (Thailand). Principal Regional Office for Asia and the Pacific.

    Adolescence Education is a family life education training program designed to assist young people in their physical, social, emotional, and moral development as they prepare for adulthood, marriage, parenthood, aging, and social relationships in the context of family and society. This package consists of four individually bound modules: (1)…

  20. Four-Year Myth: Make College More Affordable. Restore the Promise of Graduating on Time

    ERIC Educational Resources Information Center

    Complete College America, 2014

    2014-01-01

    In American higher education, it has become the accepted standard to measure graduation rates at four-year colleges on a six-year time frame. Evaluations of two-year community colleges are now based on three-year graduation rates. Metrics like these are unacceptable, especially when we consider that students and their families are trying…

  1. Fine-needle aspiration cytology of malignant hemangiopericytomas with ultrastructural and flow cytometric analyses.

    PubMed

    Geisinger, K R; Silverman, J F; Cappellari, J O; Dabbs, D J

    1990-07-01

    A hemangiopericytoma (HPC) is an uncommon soft-tissue neoplasm that may arise in many body sites. The cytologic features of fine-needle aspirates (FNAs) of HPCs have only rarely been described in the literature. We examined FNAs of malignant HPCs from the head and neck region (three) and the retroperitoneum (one) in four adults (aged 38 to 83 years). All four FNAs yielded cellular specimens that consisted of uninuclear tumor cells with high nuclear-cytoplasmic ratios. The cytomorphological spectrum included nuclei that were oval to elongate and had very finely granular, evenly distributed chromatin with one or two small but distinct nucleoli. Hemangiopericytomas yield aspirates that may be considered malignant and may suggest sarcoma. Histologically, all four neoplasms manifested high mitotic activity. The ultrastructural features of all four tumors were supportive of the diagnosis of HPC. Although a specific primary diagnosis of HPC on FNA of a soft-tissue mass is unlikely, cytologic analysis may allow diagnosis of recurrent or metastatic HPC. We were able to perform flow cytometric determinations of tumor DNA content on three of the resected neoplasms. In two, an aneuploid pattern was found, including the neoplasm with the most marked pleomorphism in the FNA. The third was diploid.

  2. Network analysis of a regional fishery: Implications for management of natural resources, and recruitment and retention of anglers

    USGS Publications Warehouse

    Martin, Dustin R.; Shizuka, Daizaburo; Chizinski, Christopher J.; Pope, Kevin L.

    2017-01-01

    Angler groups and water-body types interact to create a complex social-ecological system. Network analysis could inform detailed mechanistic models on, and provide managers better information about, basic patterns of fishing activity. Differences in behavior and reservoir selection among angler groups in a regional fishery, the Salt Valley fishery in southeastern Nebraska, USA, were assessed using a combination of cluster and network analyses. The four angler groups assessed ranged from less active, unskilled anglers (group One) to highly active, very skilled anglers (group Four). Reservoir use patterns and the resulting network communities of these four angler groups differed; the number of reservoir communities for these groups ranged from two to three and appeared to be driven by reservoir location (group One), reservoir size and its associated attributes (groups Two and Four), or an interaction between reservoir size and location (group Three). Network analysis is a useful tool to describe differences in participation among angler groups within a regional fishery, and provides new insights about possible recruitment of anglers. For example, group One anglers fished reservoirs closer to home and had a greater probability of dropping out if local reservoir access were restricted.

  3. Relationship of sleep abnormalities to patient genotypes in Prader-Willi syndrome

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vgontzas, A.N.; Kales, A.; Bixler, E.O.

    To assess whether sleep abnormalities are related to the genetic abnormalities in Prader-Willi Syndrome (PWS), we performed polysomnographic studies (nighttime and daytime) and determined the chromosome 15 genotypes in eight patients with PWS. Four patients demonstrated sleep onset REM periods (SOREM), and five met the objective polysomnographic criteria for severe or moderate excessive daytime sleepiness (EDS). Three of the four patients with SOREM displayed a paternally derived deletion of chromosome 15q11-q13, whereas the fourth exhibited maternal uniparental heterodisomy in this chromosomal region (UPD). Two of the four patients that did not display SOREM carried paternally derived deletions; the remaining twomore » demonstrated UPD. Four of the five patients with EDS displayed paternal deletions, and the fifth exhibited UPD. One of three patients without evidence of EDS demonstrated paternal deletion; the remaining two showed UPD. Although neither EDS nor SOREM was not consistently associated with a specific genetic abnormality, these phenotypes may be more common in patients with paternal deletions than in those with UPD. Sleep abnormalities in PWS cannot be explained by a single genetic model. 32 refs., 1 tab.« less

  4. Novel polymorphisms of the APOA2 gene and its promoter region affect body traits in cattle.

    PubMed

    Zhou, Yang; Li, Caixia; Cai, Hanfang; Xu, Yao; Lan, Xianyong; Lei, Chuzhao; Chen, Hong

    2013-12-01

    Apolipoprotein A-II (APOA2) is one of the major constituents of high-density lipoprotein and plays a critical role in lipid metabolism and obesity. However, similar research for the bovine APOA2 gene is lacking. In this study, polymorphisms of the bovine APOA2 gene and its promoter region were detected in 1021 cows from four breeds by sequencing and PCR-RFLP methods. Totally, we detected six novel mutations which included one mutation in the promoter region, two mutations in the exons and three mutations in the introns. There were four polymorphisms within APOA2 gene were analyzed. The allele A, T, T and G frequencies of the four loci were predominant in the four breeds when in separate or combinations analysis which suggested cows with those alleles to be more adapted to the steppe environment. The association analysis indicated three SVs in Nangyang cows, two SVs in Qinchun cows and the 9 haplotypes in Nangyang cows were significantly associated with body traits (P<0.05 or P<0.01). The results of this study suggested the bovine APOA2 gene may be a strong candidate gene for body traits in the cattle breeding program. © 2013.

  5. Population growth and development of the psocid Liposcelis rufa (Psocoptera: Liposcelididae) at constant temperatures and relative humidities.

    PubMed

    Gautam, S G; Opit, G P; Giles, K L

    2010-10-01

    We investigated the effects of eight temperatures (22.5, 25.0, 27.5, 30.0, 32.5, 35.0, 37.5, and 40.0 degrees C) and four relative humidities (43, 55, 63, and 75%) on population growth and development of the psocid Liposcelis rufa Broadhead (Psocoptera: Liposcelididae). L. rufa did not survive at 43% RH, at all temperatures tested; at 55% RH, at the highest four temperatures; and at 63% RH and 40.0 degrees C. The greatest population growth was recorded at 35.0 degrees C and 75% RH (73-fold growth). At 40.0 degrees C, L. rufa populations declined or barely grew. L. rufa males have two to four nymphal instars, and the percentages of males with two, three, and four instars were 31, 54, and 15%, respectively. Female L. rufa have two to five instars, and the percentages of females with two, three, four, and five instars were 2, 44, 42, and 12%, respectively. The life cycle was shorter for males than females. We developed temperature-dependent developmental equations for male and female eggs, individual nymphal, combined nymphal, and combined immature stages. The ability of L. rufa to reproduce at a relative humidity of 55% and temperatures of 22.5-30.0 degrees C and at relative humidities of 63-75% and temperatures of 22.5-37.5 degrees C, in addition to being able to survive at 40.0 degrees C, suggests that this species would be expected to have a broader distribution than other Liposcelis species. These data provide a better understanding of L. rufa population dynamics and can be used to help develop effective management strategies for this psocid.

  6. Part-time occlusion therapy for amblyopia in older children

    PubMed Central

    Singh, Inderpreet; Sachdev, Nishant; Kaushik, Sushmita

    2008-01-01

    Aim: To compare the efficacy of part-time versus full-time occlusion for treatment of amblyopia in children aged 7-12 years. Materials and Methods: Prospective interventional case series. One hundred children between 7-12 years of age with anisometropic (57), strabismic (25) and mixed (18) unilateral amblyopia were randomized (simple randomization) into four groups (25 each) to receive two hours, four hours, six hours or full-time occlusion therapy. Children were regularly followed up at six-weekly intervals for a minimum of three visits. Statistical Analysis: Intragroup visual improvement was analyzed using paired t-test while intergroup comparisons were done using ANOVA and unpaired t-test. Results: All four groups showed significant visual improvement after 18 weeks of occlusion therapy (P<0.001). Seventy-three (73%) of the total 100 eyes responded to amblyopia therapy with 11 eyes (44%), 17 eyes (68%), 22 eyes (88%) and 23 eyes (92%) being amblyopia responders in the four groups respectively, with the least number of responders in the two hours group. In mild to moderate amblyopia (vision 20/30 to 20/80), there was no significant difference in visual outcome among the four groups (P=0.083). However, in severe amblyopia (vision 20/100 or worse), six hours (P=0.048) and full-time occlusion (P=0.027) treatment were significantly more effective than two hours occlusion. Conclusion: All grades of part-time occlusion are comparable to full-time occlusion in effectiveness of treatment for mild to moderate amblyopia in children between 7-12 years of age unlike in severe amblyopia, where six hours and full-time occlusion were more effective than two hours occlusion therapy. PMID:18974515

  7. One Potato, Two Potato, Three Potato, Four.

    ERIC Educational Resources Information Center

    Fargnoli, Betty Ann

    1984-01-01

    Describes the unorthodox methods used by a high school English teacher to get the meaning of such literary terms as "classicism,""romanticism,""realism," and "naturalism" across to her students. (RBW)

  8. A Figure-of-Merit for Designing High-Performance Inductive Power Transmission Links

    PubMed Central

    Kiani, Mehdi; Ghovanloo, Maysam

    2014-01-01

    Power transfer efficiency (PTE) and power delivered to the load (PDL) are two key inductive link design parameters that relate to the power source and driver specs, power loss, transmission range, robustness against misalignment, variations in loading, and interference with other devices. Designers need to strike a delicate balance between these two because designing the link to achieve high PTE will degrade the PDL and vice versa. We are proposing a new figure-of-merit (FoM), which can help designers to find out whether a two-, three-, or four-coil link is appropriate for their particular application and guide them through an iterative design procedure to reach optimal coil geometries based on how they weigh the PTE versus PDL for that application. Three design examples at three different power levels have been presented based on the proposed FoM for implantable microelectronic devices, handheld mobile devices, and electric vehicles. The new FoM suggests that the two-coil links are suitable when the coils are strongly coupled, and a large PDL is needed. Three-coil links are the best when the coils are loosely coupled, the coupling distance varies considerably, and large PDL is necessary. Finally, four-coil links are optimal when the PTE is paramount, the coils are loosely coupled, and their relative distance and alignment are stable. Measurement results support the accuracy of the theoretical design procedure and conclusions. PMID:25382898

  9. A Figure-of-Merit for Designing High-Performance Inductive Power Transmission Links.

    PubMed

    Kiani, Mehdi; Ghovanloo, Maysam

    2012-11-16

    Power transfer efficiency (PTE) and power delivered to the load (PDL) are two key inductive link design parameters that relate to the power source and driver specs, power loss, transmission range, robustness against misalignment, variations in loading, and interference with other devices. Designers need to strike a delicate balance between these two because designing the link to achieve high PTE will degrade the PDL and vice versa. We are proposing a new figure-of-merit (FoM), which can help designers to find out whether a two-, three-, or four-coil link is appropriate for their particular application and guide them through an iterative design procedure to reach optimal coil geometries based on how they weigh the PTE versus PDL for that application. Three design examples at three different power levels have been presented based on the proposed FoM for implantable microelectronic devices, handheld mobile devices, and electric vehicles. The new FoM suggests that the two-coil links are suitable when the coils are strongly coupled, and a large PDL is needed. Three-coil links are the best when the coils are loosely coupled, the coupling distance varies considerably, and large PDL is necessary. Finally, four-coil links are optimal when the PTE is paramount, the coils are loosely coupled, and their relative distance and alignment are stable. Measurement results support the accuracy of the theoretical design procedure and conclusions.

  10. [Role of creative discussion in the learning of critical reading of scientific articles].

    PubMed

    Cobos-Aguilar, Héctor; Viniegra-Velázquez, Leonardo; Pérez-Cortés, Patricia

    2011-01-01

    To compare two active educational strategies on critical reading (two and three stages) for research learning in medical students. Four groups were conformed in a quasi-experimental design. The medical student group, related to three stages (critical reading guide resolution, creative discussion, group discussion) g1, n = 9 with school marks > 90 and g2, n = 19 with a < 90, respectively. The two-stage groups (guide resolution and group discussion) were conformed by pre-graduate interns, g3, n = 17 and g4, n = 12, who attended social security general hospitals. A validated and consistent survey with 144 items was applied to the four groups before and after educational strategies. Critical reading with its subcomponents: interpretation, judgment and proposal were evaluated with 47, 49 and 48 items, respectively. The case control studies, cohort studies, diagnostic test and clinical trial designs were evaluated. Nonparametric significance tests were performed to compare the groups and their results. A bias calculation was performed for each group. The highest median was obtained by the three-stage groups (g1 and g2) and so were the medians in interpretation, judgment and proposal. The several research design results were higher in the same groups. An active educational strategy with three stages is superior to another with two stages in medical students. It is advisable to perform these activities in goal of better learning in our students.

  11. Mutually unbiased bases in six dimensions: The four most distant bases

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Raynal, Philippe; Lue Xin; Englert, Berthold-Georg

    2011-06-15

    We consider the average distance between four bases in six dimensions. The distance between two orthonormal bases vanishes when the bases are the same, and the distance reaches its maximal value of unity when the bases are unbiased. We perform a numerical search for the maximum average distance and find it to be strictly smaller than unity. This is strong evidence that no four mutually unbiased bases exist in six dimensions. We also provide a two-parameter family of three bases which, together with the canonical basis, reach the numerically found maximum of the average distance, and we conduct a detailedmore » study of the structure of the extremal set of bases.« less

  12. Two-dimensional strain-mapping by electron backscatter diffraction and confocal Raman spectroscopy

    NASA Astrophysics Data System (ADS)

    Gayle, Andrew J.; Friedman, Lawrence H.; Beams, Ryan; Bush, Brian G.; Gerbig, Yvonne B.; Michaels, Chris A.; Vaudin, Mark D.; Cook, Robert F.

    2017-11-01

    The strain field surrounding a spherical indentation in silicon is mapped in two dimensions (2-D) using electron backscatter diffraction (EBSD) cross-correlation and confocal Raman spectroscopy techniques. The 200 mN indentation created a 4 μm diameter residual contact impression in the silicon (001) surface. Maps about 50 μm × 50 μm area with 128 pixels × 128 pixels were generated in several hours, extending, by comparison, assessment of the accuracy of both techniques to mapping multiaxial strain states in 2-D. EBSD measurements showed a residual strain field dominated by in-surface normal and shear strains, with alternating tensile and compressive lobes extending about three to four indentation diameters from the contact and exhibiting two-fold symmetry. Raman measurements showed a residual Raman shift field, dominated by positive shifts, also extending about three to four indentation diameters from the contact but exhibiting four-fold symmetry. The 2-D EBSD results, in combination with a mechanical-spectroscopic analysis, were used to successfully predict the 2-D Raman shift map in scale, symmetry, and shift magnitude. Both techniques should be useful in enhancing the reliability of microelectromechanical systems (MEMS) through identification of the 2-D strain fields in MEMS devices.

  13. Development and fabrication of large vented nickel-zinc cells

    NASA Technical Reports Server (NTRS)

    Donnel, C. P., III

    1975-01-01

    A preliminary cell design for a 300AH vented nickel-zinc cell was established based on volume requirements and cell component materials selected by NASA Lewis Research Center. A 100AH cell configuration was derived from the 300AH cell design utilizing the same size electrodes, separators, and cell terminal hardware. The first cells fabricated were four groups of three cells each in the 100AH size. These 100AH experimental nickel-zinc cells had as common components the nickel positive electrodes (GFM), flexible inorganic separator (GFM) bags on the negative electrodes, pressed powder zinc oxide electrodes, and cell containers with hardware. The variations introduced were four differing electrolyte absorber (interseparator) systems used to encase the nickel positive electrodes of each cell group. The four groups of 100AH experimental vented nickel-zinc cells were tested to determine, based on cell performance, the best two interseparator systems. Using the two interseparator systems, two groups of experimental 300AH cells were fabricated. Each group of three cells differed only in the interseparator material used. The six cells were filled, formed and tested to evaluate the interseparator materials and investigate the performance characteristics of the 300AH cell configuration and its components.

  14. Schemes for deterministic joint remote preparation of an arbitrary tripartite four-qubit entangled state

    NASA Astrophysics Data System (ADS)

    Ma, Peng-Cheng; Chen, Gui-Bin; Li, Xiao-Wei; Zhan, You-Bang

    2016-10-01

    We present two schemes for the joint remote state preparation (JRSP) of an arbitrary tripartite four-qubit entangled state with complex coefficients via four and two three-qubit GHZ states as the quantum channel, respectively. In these schemes, the two senders share the original state which they wish to help the receiver remotely prepare. To complete the JRSP schemes, some novel sets of mutually orthogonal basis vectors are introduced. It is shown that, only if the two senders collaborate with each other, and perform projective measurements under a suitable measuring basis on their own qubits respectively, can the receiver reconstruct the original state by means of some appropriate unitary operations. We demonstrate, in our both schemes, the total success probability of the JRSP can reach 1. Moreover, compared with the first scheme in this paper, the advantage of the second scheme is that the entanglement resource can be reduced.

  15. Quantum entanglement properties of geometrical and topological quantum gates

    NASA Astrophysics Data System (ADS)

    Sezer, Hasan Cavit; Duy, Hoang Ngoc; Heydari, Hoshang

    2011-03-01

    In this paper we will investigate the action of holonomic and topological quantum gates on different classes of four qubit states. In particular, we review the construction of holonomic quantum gate based on geometric phase and topological quantum gate based on braid group. Then, we investigate the entanglement properties of three different classes of four-qubit states based on geometric invariants. The result shows that entanglement properties of the two most generic classes of four-qubit states can be controlled by holonomic and topological quantum gate..

  16. Four infants presenting with severe vomiting in solid food protein-induced enterocolitis syndrome: a case series.

    PubMed

    Bansal, Amolak S; Bhaskaran, Sree; Bansal, Rhea A

    2012-06-26

    Several different foods have been implicated in inducing the delayed and very significant vomiting and sometimes diarrhea that occurs in food protein-induced enterocolitis syndrome. While immunoglobulin E is not involved, the mechanism(s) that result in the food-induced gastrointestinal symptoms are unclear, although T cell activation has been considered. We report four cases of food protein-induced enterocolitis syndrome caused by different solid foods and without concomitant immunoglobulin E sensitization to milk and soya. Clinical and laboratory evidence of type I immunoglobulin E mediated food reactivity and food-induced T cell activation was absent in each case. Case 1 concerned a 20-month-old South Asian boy who had experienced four episodes of severe vomiting with flaccidity since four months of age and two hours after consuming rice.Case 2 involved a nine-month-old Caucasian boy who had suffered three episodes of severe vomiting with flaccidity since six months of age and three hours after consuming wheat.The child in Case 3 was a 16-month-old Caucasian boy who had suffered three episodes of severe vomiting with flaccidity since nine months of age and two hours after consuming cod.Case 4 involved a 15-month-old South Asian boy who had suffered three episodes of severe vomiting since eight months of age and two hours after consuming chicken. In children with recurrent marked delayed vomiting after the ingestion of specific foods and in whom bronchospasm, skin rash and angioedema are absent, food protein-induced enterocolitis syndrome should be considered. Skin prick testing and specific immunoglobulin E antibodies are negative and the mechanism of the vomiting is unclear. We speculate whether food protein-induced oligoclonal T cell activation may be present. This has similarities to various animal models and improvement may involve deletion of these T cells.

  17. Distributions of topological observables in inclusive three- and four-jet events in pp collisions at [Formula: see text][Formula: see text].

    PubMed

    Khachatryan, V; Sirunyan, A M; Tumasyan, A; Adam, W; Bergauer, T; Dragicevic, M; Erö, J; Friedl, M; Frühwirth, R; Ghete, V M; Hartl, C; Hörmann, N; Hrubec, J; Jeitler, M; Kiesenhofer, W; Knünz, V; Krammer, M; Krätschmer, I; Liko, D; Mikulec, I; Rabady, D; Rahbaran, B; Rohringer, H; Schöfbeck, R; Strauss, J; Treberer-Treberspurg, W; Waltenberger, W; Wulz, C-E; Mossolov, V; Shumeiko, N; Suarez Gonzalez, J; Alderweireldt, S; Bansal, S; Cornelis, T; De Wolf, E A; Janssen, X; Knutsson, A; Lauwers, J; Luyckx, S; Ochesanu, S; Rougny, R; Van De Klundert, M; Van Haevermaet, H; Van Mechelen, P; Van Remortel, N; Van Spilbeeck, A; Blekman, F; Blyweert, S; D'Hondt, J; Daci, N; Heracleous, N; Keaveney, J; Lowette, S; Maes, M; Olbrechts, A; Python, Q; Strom, D; Tavernier, S; Van Doninck, W; Van Mulders, P; Van Onsem, G P; Villella, I; Caillol, C; Clerbaux, B; De Lentdecker, G; Dobur, D; Favart, L; Gay, A P R; Grebenyuk, A; Léonard, A; Mohammadi, A; Perniè, L; Randle-Conde, A; Reis, T; Seva, T; Thomas, L; Vander Velde, C; Vanlaer, P; Wang, J; Zenoni, F; Adler, V; Beernaert, K; Benucci, L; Cimmino, A; Costantini, S; Crucy, S; Dildick, S; Fagot, A; Garcia, G; Mccartin, J; Ocampo Rios, A A; Ryckbosch, D; Salva Diblen, S; Sigamani, M; Strobbe, N; Thyssen, F; Tytgat, M; Yazgan, E; Zaganidis, N; Basegmez, S; Beluffi, C; Bruno, G; Castello, R; Caudron, A; Ceard, L; Da Silveira, G G; Delaere, C; du Pree, T; Favart, D; Forthomme, L; Giammanco, A; Hollar, J; Jafari, A; Jez, P; Komm, M; Lemaitre, V; Nuttens, C; Pagano, D; Perrini, L; Pin, A; Piotrzkowski, K; Popov, A; Quertenmont, L; Selvaggi, M; Vidal Marono, M; Vizan Garcia, J M; Beliy, N; Caebergs, T; Daubie, E; Hammad, G H; Júnior, W L Aldá; Alves, G A; Brito, L; Correa Martins Junior, M; Martins, T Dos Reis; Mora Herrera, C; Pol, M E; Rebello Teles, P; Carvalho, W; Chinellato, J; Custódio, A; Da Costa, E M; De Jesus Damiao, D; De Oliveira Martins, C; Fonseca De Souza, S; Malbouisson, H; Matos Figueiredo, D; Mundim, L; Nogima, H; Prado Da Silva, W L; Santaolalla, J; Santoro, A; Sznajder, A; Tonelli Manganote, E J; Vilela Pereira, A; Bernardes, C A; Dogra, S; Fernandez Perez Tomei, T R; Gregores, E M; Mercadante, P G; Novaes, S F; Padula, Sandra S; Aleksandrov, A; Genchev, V; Hadjiiska, R; Iaydjiev, P; Marinov, A; Piperov, S; Rodozov, M; Sultanov, G; Vutova, M; Dimitrov, A; Glushkov, I; Litov, L; Pavlov, B; Petkov, P; Bian, J G; Chen, G M; Chen, H S; Chen, M; Cheng, T; Du, R; Jiang, C H; Plestina, R; Romeo, F; Tao, J; Wang, Z; Asawatangtrakuldee, C; Ban, Y; Li, Q; Liu, S; Mao, Y; Qian, S J; Wang, D; Xu, Z; Zou, W; Avila, C; Cabrera, A; Chaparro Sierra, L F; Florez, C; Gomez, J P; Gomez Moreno, B; Sanabria, J C; Godinovic, N; Lelas, D; Polic, D; Puljak, I; Antunovic, Z; Kovac, M; Brigljevic, V; Kadija, K; Luetic, J; Mekterovic, D; Sudic, L; Attikis, A; Mavromanolakis, G; Mousa, J; Nicolaou, C; Ptochos, F; Razis, P A; Bodlak, M; Finger, M; Finger, M; Assran, Y; Ellithi Kamel, A; Mahmoud, M A; Radi, A; Kadastik, M; Murumaa, M; Raidal, M; Tiko, A; Eerola, P; Fedi, G; Voutilainen, M; Härkönen, J; Karimäki, V; Kinnunen, R; Kortelainen, M J; Lampén, T; Lassila-Perini, K; Lehti, S; Lindén, T; Luukka, P; Mäenpää, T; Peltola, T; Tuominen, E; Tuominiemi, J; Tuovinen, E; Wendland, L; Talvitie, J; Tuuva, T; Besancon, M; Couderc, F; Dejardin, M; Denegri, D; Fabbro, B; Faure, J L; Favaro, C; Ferri, F; Ganjour, S; Givernaud, A; Gras, P; Hamel de Monchenault, G; Jarry, P; Locci, E; Malcles, J; Rander, J; Rosowsky, A; Titov, M; Baffioni, S; Beaudette, F; Busson, P; Charlot, C; Dahms, T; Dalchenko, M; Dobrzynski, L; Filipovic, N; Florent, A; Granier de Cassagnac, R; Mastrolorenzo, L; Miné, P; Mironov, C; Naranjo, I N; Nguyen, M; Ochando, C; Ortona, G; Paganini, P; Regnard, S; Salerno, R; Sauvan, J B; Sirois, Y; Veelken, C; Yilmaz, Y; Zabi, A; Agram, J-L; Andrea, J; Aubin, A; Bloch, D; Brom, J-M; Chabert, E C; Collard, C; Conte, E; Fontaine, J-C; Gelé, D; Goerlach, U; Goetzmann, C; Le Bihan, A-C; Skovpen, K; Van Hove, P; Gadrat, S; Beauceron, S; Beaupere, N; Boudoul, G; Bouvier, E; Brochet, S; Carrillo Montoya, C A; Chasserat, J; Chierici, R; Contardo, D; Depasse, P; El Mamouni, H; Fan, J; Fay, J; Gascon, S; Gouzevitch, M; Ille, B; Kurca, T; Lethuillier, M; Mirabito, L; Perries, S; Ruiz Alvarez, J D; Sabes, D; Sgandurra, L; Sordini, V; Vander Donckt, M; Verdier, P; Viret, S; Xiao, H; Tsamalaidze, Z; Autermann, C; Beranek, S; Bontenackels, M; Edelhoff, M; Feld, L; Heister, A; Hindrichs, O; Klein, K; Ostapchuk, A; Raupach, F; Sammet, J; Schael, S; Schulte, J F; Weber, H; Wittmer, B; Zhukov, V; Ata, M; Brodski, M; Dietz-Laursonn, E; Duchardt, D; Erdmann, M; Fischer, R; Güth, A; Hebbeker, T; Heidemann, C; Hoepfner, K; Klingebiel, D; Knutzen, S; Kreuzer, P; Merschmeyer, M; Meyer, A; Millet, P; Olschewski, M; Padeken, K; Papacz, P; Reithler, H; Schmitz, S A; Sonnenschein, L; Teyssier, D; Thüer, S; Weber, M; Cherepanov, V; Erdogan, Y; Flügge, G; Geenen, H; Geisler, M; Haj Ahmad, W; Hoehle, F; Kargoll, B; Kress, T; Kuessel, Y; Künsken, A; 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Valuev, V; Weber, M; Burt, K; Clare, R; Ellison, J; Gary, J W; Hanson, G; Heilman, J; Ivova Rikova, M; Jandir, P; Kennedy, E; Lacroix, F; Long, O R; Luthra, A; Malberti, M; Negrete, M Olmedo; Shrinivas, A; Sumowidagdo, S; Wimpenny, S; Branson, J G; Cerati, G B; Cittolin, S; D'Agnolo, R T; Holzner, A; Kelley, R; Klein, D; Letts, J; Macneill, I; Olivito, D; Padhi, S; Palmer, C; Pieri, M; Sani, M; Sharma, V; Simon, S; Tadel, M; Tu, Y; Vartak, A; Welke, C; Würthwein, F; Yagil, A; Barge, D; Bradmiller-Feld, J; Campagnari, C; Danielson, T; Dishaw, A; Dutta, V; Flowers, K; Franco Sevilla, M; Geffert, P; George, C; Golf, F; Gouskos, L; Incandela, J; Justus, C; Mccoll, N; Richman, J; Stuart, D; To, W; West, C; Yoo, J; Apresyan, A; Bornheim, A; Bunn, J; Chen, Y; Duarte, J; Mott, A; Newman, H B; Pena, C; Pierini, M; Spiropulu, M; Vlimant, J R; Wilkinson, R; Xie, S; Zhu, R Y; Azzolini, V; Calamba, A; Carlson, B; Ferguson, T; Iiyama, Y; Paulini, M; Russ, J; Vogel, H; Vorobiev, I; Cumalat, J P; Ford, W T; Gaz, A; Krohn, M; Luiggi Lopez, E; Nauenberg, U; Smith, J G; Stenson, K; Wagner, S R; Alexander, J; Chatterjee, A; Chaves, J; Chu, J; Dittmer, S; Eggert, N; Mirman, N; Nicolas Kaufman, G; Patterson, J R; Ryd, A; Salvati, E; Skinnari, L; Sun, W; Teo, W D; Thom, J; Thompson, J; Tucker, J; Weng, Y; Winstrom, L; Wittich, P; Winn, D; Abdullin, S; Albrow, M; Anderson, J; Apollinari, G; Bauerdick, L A T; Beretvas, A; Berryhill, J; Bhat, P C; Bolla, G; Burkett, K; Butler, J N; Cheung, H W K; Chlebana, F; Cihangir, S; Elvira, V D; Fisk, I; Freeman, J; Gao, Y; Gottschalk, E; Gray, L; Green, D; Grünendahl, S; Gutsche, O; Hanlon, J; Hare, D; Harris, R M; Hirschauer, J; Hooberman, B; Jindariani, S; Johnson, M; Joshi, U; Kaadze, K; Klima, B; Kreis, B; Kwan, S; Linacre, J; Lincoln, D; Lipton, R; Liu, T; Lykken, J; Maeshima, K; Marraffino, J M; Martinez Outschoorn, V I; Maruyama, S; Mason, D; McBride, P; Merkel, P; Mishra, K; Mrenna, S; Nahn, S; Newman-Holmes, C; O'Dell, V; Prokofyev, O; Sexton-Kennedy, E; Sharma, S; Soha, A; Spalding, W J; Spiegel, L; Taylor, L; Tkaczyk, S; Tran, N V; Uplegger, L; Vaandering, E W; Vidal, R; Whitbeck, A; Whitmore, J; Yang, F; Acosta, D; Avery, P; Bortignon, P; Bourilkov, D; Carver, M; Curry, D; Das, S; De Gruttola, M; Di Giovanni, G P; Field, R D; Fisher, M; Furic, I K; Hugon, J; Konigsberg, J; Korytov, A; Kypreos, T; Low, J F; Matchev, K; Mei, H; Milenovic, P; Mitselmakher, G; Muniz, L; Rinkevicius, A; Shchutska, L; Snowball, M; Sperka, D; Yelton, J; Zakaria, M; Hewamanage, S; Linn, S; Markowitz, P; Martinez, G; Rodriguez, J L; Adams, T; Askew, A; Bochenek, J; Diamond, B; Haas, J; Hagopian, S; Hagopian, V; Johnson, K F; Prosper, H; Veeraraghavan, V; Weinberg, M; Baarmand, M M; Hohlmann, M; Kalakhety, H; Yumiceva, F; Adams, M R; Apanasevich, L; Berry, D; Betts, R R; Bucinskaite, I; Cavanaugh, R; Evdokimov, O; Gauthier, L; Gerber, C E; Hofman, D J; Kurt, P; Moon, D H; O'Brien, C; Sandoval Gonzalez, L D; Silkworth, C; Turner, P; Varelas, N; Bilki, B; Clarida, W; Dilsiz, K; Haytmyradov, M; Merlo, J-P; Mermerkaya, H; Mestvirishvili, A; Moeller, A; Nachtman, J; Ogul, H; Onel, Y; Ozok, F; Penzo, A; Rahmat, R; Sen, S; Tan, P; Tiras, E; Wetzel, J; Yi, K; Barnett, B A; Blumenfeld, B; Bolognesi, S; Fehling, D; Gritsan, A V; Maksimovic, P; Martin, C; Swartz, M; Baringer, P; Bean, A; Benelli, G; Bruner, C; Kenny, R P; Malek, M; Murray, M; Noonan, D; Sanders, S; Sekaric, J; Stringer, R; Wang, Q; Wood, J S; Chakaberia, I; Ivanov, A; Khalil, S; Makouski, M; Maravin, Y; Saini, L K; Skhirtladze, N; Svintradze, I; Gronberg, J; Lange, D; Rebassoo, F; Wright, D; Baden, A; Belloni, A; Calvert, B; Eno, S C; Gomez, J A; Hadley, N J; Kellogg, R G; Kolberg, T; Lu, Y; Mignerey, A C; Pedro, K; Skuja, A; Tonjes, M B; Tonwar, S C; Apyan, A; Barbieri, R; Busza, W; Cali, I A; Chan, M; Di Matteo, L; Gomez Ceballos, G; Goncharov, M; Gulhan, D; Klute, M; Lai, Y S; Lee, Y-J; Levin, A; Luckey, P D; Paus, C; Ralph, D; Roland, C; Roland, G; Stephans, G S F; Sumorok, K; Velicanu, D; Veverka, J; Wyslouch, B; Yang, M; Zanetti, M; Zhukova, V; Dahmes, B; Gude, A; Kao, S C; Klapoetke, K; Kubota, Y; Mans, J; Pastika, N; Rusack, R; Singovsky, A; Tambe, N; Turkewitz, J; Acosta, J G; Oliveros, S; Avdeeva, E; Bloom, K; Bose, S; Claes, D R; Dominguez, A; Gonzalez Suarez, R; Keller, J; Knowlton, D; Kravchenko, I; Lazo-Flores, J; Meier, F; Ratnikov, F; Snow, G R; Zvada, M; Dolen, J; Godshalk, A; Iashvili, I; Kharchilava, A; Kumar, A; Rappoccio, S; Alverson, G; Barberis, E; Baumgartel, D; Chasco, M; Massironi, A; Morse, D M; Nash, D; Orimoto, T; Trocino, D; Wang, R J; Wood, D; Zhang, J; Hahn, K A; Kubik, A; Mucia, N; Odell, N; Pollack, B; Pozdnyakov, A; Schmitt, M; Stoynev, S; Sung, K; Velasco, M; Won, S; Brinkerhoff, A; Chan, K M; Drozdetskiy, A; Hildreth, M; Jessop, C; Karmgard, D J; Kellams, N; Lannon, K; Lynch, S; Marinelli, N; Musienko, Y; Pearson, T; Planer, M; Ruchti, R; Smith, G; Valls, N; Wayne, M; Wolf, M; Woodard, A; Antonelli, L; Brinson, J; Bylsma, B; Durkin, L S; Flowers, S; Hart, A; Hill, C; Hughes, R; Kotov, K; Ling, T Y; Luo, W; Puigh, D; Rodenburg, M; Winer, B L; Wolfe, H; Wulsin, H W; Driga, O; Elmer, P; Hardenbrook, J; Hebda, P; Hunt, A; Koay, S A; Lujan, P; Marlow, D; Medvedeva, T; Mooney, M; Olsen, J; Piroué, P; Quan, X; Saka, H; Stickland, D; Tully, C; Werner, J S; Zuranski, A; Brownson, E; Malik, S; Mendez, H; Ramirez Vargas, J E; Barnes, V E; Benedetti, D; Bortoletto, D; De Mattia, M; Gutay, L; Hu, Z; Jha, M K; Jones, M; Jung, K; Kress, M; Leonardo, N; Miller, D H; Neumeister, N; Radburn-Smith, B C; Shi, X; Shipsey, I; Silvers, D; Svyatkovskiy, A; Wang, F; Xie, W; Xu, L; Zablocki, J; Parashar, N; Stupak, J; Adair, A; Akgun, B; Ecklund, K M; Geurts, F J M; Li, W; Michlin, B; Padley, B P; Redjimi, R; Roberts, J; Zabel, J; Betchart, B; Bodek, A; Covarelli, R; de Barbaro, P; Demina, R; Eshaq, Y; Ferbel, T; Garcia-Bellido, A; Goldenzweig, P; Han, J; Harel, A; Khukhunaishvili, A; Korjenevski, S; Petrillo, G; Vishnevskiy, D; Ciesielski, R; Demortier, L; Goulianos, K; Mesropian, C; Arora, S; Barker, A; Chou, J P; Contreras-Campana, C; Contreras-Campana, E; Duggan, D; Ferencek, D; Gershtein, Y; Gray, R; Halkiadakis, E; Hidas, D; Kaplan, S; Lath, A; Panwalkar, S; Park, M; Patel, R; Salur, S; Schnetzer, S; Somalwar, S; Stone, R; Thomas, S; Thomassen, P; Walker, M; Rose, K; Spanier, S; York, A; Bouhali, O; Castaneda Hernandez, A; Eusebi, R; Flanagan, W; Gilmore, J; Kamon, T; Khotilovich, V; Krutelyov, V; Montalvo, R; Osipenkov, I; Pakhotin, Y; Perloff, A; Roe, J; Rose, A; Safonov, A; Suarez, I; Tatarinov, A; Ulmer, K A; Akchurin, N; Cowden, C; Damgov, J; Dragoiu, C; Dudero, P R; Faulkner, J; Kovitanggoon, K; Kunori, S; Lee, S W; Libeiro, T; Volobouev, I; Appelt, E; Delannoy, A G; Greene, S; Gurrola, A; Johns, W; Maguire, C; Mao, Y; Melo, A; Sharma, M; Sheldon, P; Snook, B; Tuo, S; Velkovska, J; Arenton, M W; Boutle, S; Cox, B; Francis, B; Goodell, J; Hirosky, R; Ledovskoy, A; Li, H; Lin, C; Neu, C; Wood, J; Clarke, C; Harr, R; Karchin, P E; Kottachchi Kankanamge Don, C; Lamichhane, P; Sturdy, J; Belknap, D A; Carlsmith, D; Cepeda, M; Dasu, S; Dodd, L; Duric, S; Friis, E; Hall-Wilton, R; Herndon, M; Hervé, A; Klabbers, P; Lanaro, A; Lazaridis, C; Levine, A; Loveless, R; Mohapatra, A; Ojalvo, I; Perry, T; Pierro, G A; Polese, G; Ross, I; Sarangi, T; Savin, A; Smith, W H; Taylor, D; Vuosalo, C; Woods, N

    This paper presents distributions of topological observables in inclusive three- and four-jet events produced in pp collisions at a centre-of-mass energy of 7[Formula: see text] with a data sample collected by the CMS experiment corresponding to a luminosity of 5.1[Formula: see text]. The distributions are corrected for detector effects, and compared with several event generators based on two- and multi-parton matrix elements at leading order. Among the considered calculations, MadGraph interfaced with pythia6 displays the overall best agreement with data.

  18. Distributions of topological observables in inclusive three- and four-jet events in pp collisions at √s = 7 TeV

    DOE PAGES

    Khachatryan, Vardan

    2015-07-01

    This paper presents distributions of topological observables in inclusive three- and four-jet events produced in pp collisions at a centre-of-mass energy of 7TeV with a data sample collected by the CMS experiment corresponding to a luminosity of 5.1fb -1. We corrected the distributions for detector effects, and compared with several event generators based on two- and multi-parton matrix elements at leading order. Thus, among the considered calculations, MADGRAPH interfaced with PYTHIA6displays the overall best agreement with data.

  19. Financial performance in the social health maintenance organization, 1985-88

    PubMed Central

    Leutz, Walter; Malone, Joelyn; Kistner, Marlin; O'Bar, Tim; Ripley, Jeanne M.; Sandhaus, Martin

    1990-01-01

    Since early 1985, four social health maintenance organizations have delivered integrated health and long-term care services to Medicare beneficiaries under congressionally mandated waivers that included shared public-program risk for losses. Three of four sites had substantial losses in the first 3 years, primarily because of slow enrollment and resultant high marketing and administrative costs. After assuming full risk, two of the three showed surpluses in 1988. Service and management costs for expanded long-term care were similar across sites and were affordable within the framework of Medicare and Medicaid reimbursement and private premiums. PMID:10113466

  20. Fulfilling human resources development goal in West Africa: can the training of ophthalmologist diplomates be improved?

    PubMed

    Ayanniyi, A A; Taoheed, A A

    2009-05-01

    To ascertain the perspectives of Trainee Ophthalmologist Diplomats (TOD) on the Ophthalmic Diploma Training (ODT) in West Africa with a view to improving the programme. A survey of set 2005 TOD on ODT was carried out in Ghana, 2006. The trainees included 10 (83.35%) males and two (16.7%) females whose ages ranged between thirty-two and fifty-one years. The sponsors of the trainees included Sight Savers International, five (41.7%); Christian Blind Mission International, three (25.0%); Eye Foundation, Lagos, Nigeria two (16.7%); Ministry of Defence Nigeria, one (8.3%); and Health Authority Ghana, one (8.3%). Nine trainees (75.0%) felt the programme was well structured, training allowances were adequate eight (66.7%) and inadequate four (33.3%). Eleven (91.7%) trainees would work wherever they were posted; ten (83.3%) trainees had sense of fulfillment and three (25%) would like to proceed for residency training. All trainees were at least good in chalazion surgery and treatment of common medical eye conditions. Majority were at least good in eye surgery like cataract, eleven (91.7%); trabeculectomy nine (75.0%); pterygium 10 (83.3%); eyelid, eight (66.7%); destructive 11 (91.6%) and refraction 9 (75.0%). Some trainees' perceived problems included inadequate sponsorship (33.3%), short duration of the course four (33.3%) and poor accommodation facility two (16.7%). However, trainees' suggested increase in training posts, four (33.3); training allowance three (25.0%); and incentives for trainers/training hospitals two (16.7%). The ODT programme ensures ophthalmic manpower for secondary eye care level despite challenges. The stakeholders should look into problems facing the programme in order to improve it.

  1. Poly[[(μ2-acetato-κ3 O,O′:O′)aqua­bis­(μ3-isonicotinato-κ3 O:O′:N)samarium(III)silver(I)] perchlorate

    PubMed Central

    Zhu, Li-Cai; Zhu, Si-Ming

    2011-01-01

    The title compound, {[AgSm(C6H4NO2)2(CH3CO2)(H2O)]ClO4}n, is a three-dimensional heterobimetallic complex constructed from a repeating dimeric unit. Only half of the dimeric moiety is found in the asymmetric unit; the unit cell is completed by crystallographic inversion symmetry. The SmIII ion is eight-coordinated by four O atoms of four different isonicotinate ligands, three O atoms of two different acetate ligands, and one O atom of a water mol­ecule. The two-coordinate AgI ion is bonded to two N atoms of two different isonicotinate anions, thereby connecting the disamarium units. In addition, the isonicotinate ligands also act as bridging ligands, generating a three-dimensional network. The coordinated water mol­ecules link the carboxyl­ate group and acetate ligands by O—H⋯O hydrogen bonding. Another O—H⋯O hydrogen bond is observed in the crystal structure. The perchlorate ion is disordered over two sites with site-occupancy factors of 0.560 (11) and 0.440 (11), whereas the methyl group of the acetate ligand is disordered over two sites with site-occupancy factors of 0.53 (5) and 0.47 (5). PMID:22090841

  2. Cosmetic surgery volume and its correlation with the major US stock market indices.

    PubMed

    Gordon, Chad R; Pryor, Landon; Afifi, Ahmed M; Benedetto, Paul X; Langevin, C J; Papay, Francis; Yetman, Randall; Zins, James E

    2010-01-01

    As a consumer-driven industry, cosmetic plastic surgery is subject to ebbs and flows as the economy changes. There have been many predictions about the short, intermediate, and long-term impact on cosmetic plastic surgery as a result of difficulties in the current economic climate, but no studies published in the literature have quantified a direct correlation. The authors investigate a possible correlation between cosmetic surgery volume and the economic trends of the three major US stock market indices. A volume analysis for the time period from January 1992 to October 2008 was performed (n = 7360 patients, n = 8205 procedures). Four cosmetic procedures-forehead lift (FL), rhytidectomy (Rh), breast augmentation (BA), and liposuction (Li)-were chosen; breast reduction (BRd), breast reconstruction (BRc), and carpal tunnel release (CTR) were selected for comparison. Case volumes for each procedure and fiscal quarter were compared to the trends of the S&P 500, Dow Jones (DOW), and NASDAQ (NASD) indices. Pearson correlation statistics were used to evaluate a relationship between the market index trends and surgical volume. P values <.05 were considered statistically significant. Three of the four cosmetic surgery procedures investigated (Rh, n = 1540; Li, n = 1291; BA, n = 1959) demonstrated a direct (ie, positive) statistical correlation to all three major market indices. FL (n =312) only correlated to the NASD (P = .021) and did not reach significance with the S&P 500 (P = .077) or DOW (P = .14). BRd and BRc demonstrated a direct correlation to two of the three stock market indices, whereas CTR showed an inverse (ie, negative) correlation to two of the three indices. This study, to our knowledge, is the first to suggest a direct correlation of four cosmetic and two reconstructive plastic surgery procedures to the three major US stock market indices and further emphasizes the importance of a broad-based plastic surgery practice in times of economic recession.

  3. Minimally differentiated erythroleukaemia (AML M6 'variant'): a rare subset of AML distinct from AML M6. Groupe Français d'Hématologie Cellulaire.

    PubMed

    Garand, R; Duchayne, E; Blanchard, D; Robillard, N; Kuhlein, E; Fenneteau, O; Salomon-Nguyen, F; Grange, M J; Rousselot, P; Demur, C

    1995-08-01

    We describe eight cases of erythroleukaemia distinct from FAB-AML M6, which demonstrate minimal erythroid differentiation not associated with a myeloblastic component. Three infants (including a Down's syndrome) and two adults presented with a de novo leukaemia. One case was preceded by an untreated refractory anaemia with excess of blasts and one by polycythaemia vera. One case presented with an inaugural blast crisis of chronic myeloid leukaemia. In four patients the leukaemic cells showed a proerythroblast-like morphology. The four other were initially classified as undifferentiated AL (two cases) or AML MO (two cases) because of the immature aspect of the cells, their lack of myeloperoxidase activity and the absence of B, T lymphoid and myeloid (My) marker expressions apart from the CD33 antigen. Immunophenotyping in three cases showed an immature erythroblast profile (glycophorins A and B+, spectrin+). In the five others the erythroid nature was recognized by the expression of ABH blood group system on fresh cells (four cases) and glycophorin A on cells after 3 d in vitro culture with erythropoietin (EPO) + IL3 (two cases). Moreover, an erythroid colony growth of leukaemic origin was observed in three patients. In conclusion, the study of erythroid marker expression is of particular importance when immunophenotyping leukaemic cells with a proerythroblast-like morphology or an undifferentiated aspect and a HLA DR-, CD36++, B-, T-, My- (CD33 +/-) phenotype. We propose the term AML M6 'variant' for this rare type of AML.

  4. Robotic Arm Manipulator Using Active Control for Sample Acquisition and Transfer, and Passive Mode for Surface Compliance

    NASA Technical Reports Server (NTRS)

    Liu, Jun; Underhill, Michael L.; Trease, Brian P.; Lindemann, Randel A.

    2010-01-01

    A robotic arm that consists of three joints with four degrees of freedom (DOF) has been developed. It can carry an end-effector to acquire and transfer samples by using active control and comply with surface topology in a passive mode during a brief surface contact. The three joints are arranged in such a way that one joint of two DOFs is located at the shoulder, one joint of one DOF is located at the elbow, and one joint of one DOF is located at the wrist. Operationally, three DOFs are moved in the same plane, and the remaining one on the shoulder is moved perpendicular to the other three for better compliance with ground surface and more flexibility of sample handling. Three out of four joints are backdriveable, making the mechanism less complex and more cost effective

  5. Personality and Strategy: How the Personalities of General MacArthur and Admiral King Shaped Allied Strategy in the Pacific in World War Two

    DTIC Science & Technology

    2002-05-31

    one corner of New Mexico to another.9 While it is unlikely that a four - year -old kept pace at the head of the column for very...final year . Not surprisingly Reminiscences contains no mention of the incident above. In fact his memoirs spend only three brief pages on the four years ...dominant personalities 4 of two men primarily directing the course of the war, yields a highly illuminating case study in the influence of

  6. Instantons and Massless Fermions in Two Dimensions

    DOE R&D Accomplishments Database

    Callan, C. G. Jr.; Dashen, R.; Gross, D. J.

    1977-05-01

    The role of instantons in the breakdown of chiral U(N) symmetry is studied in a two dimensional model. Chiral U(1) is always destroyed by the axial vector anomaly. For N = 2 chiral SU(N) is also spontaneously broken yielding massive fermions and three (decoupled) Goldstone bosons. For N greater than or equal to 3 the fermions remain massless. Realistic four dimensional theories are believed to behave in a similar way but the critical N above which the fermions cease to be massive is not known in four dimensions.

  7. System For Characterizing Three-Phase Brushless dc Motors

    NASA Technical Reports Server (NTRS)

    Howard, David E.; Smith, Dennis A.

    1996-01-01

    System of electronic hardware and software developed to automate measurements and calculations needed to characterize electromechanical performances of three-phase brushless dc motors, associated shaft-angle sensors needed for commutation, and associated brushless tachometers. System quickly takes measurements on all three phases of motor, tachometer, and shaft-angle sensor simultaneously and processes measurements into performance data. Also useful in development and testing of motors with not only three phases but also two, four, or more phases.

  8. Advantage of four-electrode over two-electrode defibrillators

    NASA Astrophysics Data System (ADS)

    Bragard, J.; Šimić, A.; Laroze, D.; Elorza, J.

    2015-12-01

    Defibrillation is the standard clinical treatment used to stop ventricular fibrillation. An electrical device delivers a controlled amount of electrical energy via a pair of electrodes in order to reestablish a normal heart rate. We propose a technique that is a combination of biphasic shocks applied with a four-electrode system rather than the standard two-electrode system. We use a numerical model of a one-dimensional ring of cardiac tissue in order to test and evaluate the benefit of this technique. We compare three different shock protocols, namely a monophasic and two types of biphasic shocks. The results obtained by using a four-electrode system are compared quantitatively with those obtained with the standard two-electrode system. We find that a huge reduction in defibrillation threshold is achieved with the four-electrode system. For the most efficient protocol (asymmetric biphasic), we obtain a reduction in excess of 80% in the energy required for a defibrillation success rate of 90%. The mechanisms of successful defibrillation are also analyzed. This reveals that the advantage of asymmetric biphasic shocks with four electrodes lies in the duration of the cathodal and anodal phase of the shock.

  9. The efficacy of choline magnesium trisalicylate (CMT) in the management of metastatic bone pain: a pilot study.

    PubMed

    Johnson, J R; Miller, A J

    1994-01-01

    Twenty-six patients with painful, bony metastases were recruited into a randomized, double-blind, single dose, two-treatment, three-part crossover study of choline magnesium trisalicylate (CMT) and placebo. Assessments were made prior to and at one, two, three and four hours after dosing. Bone pain caused by metastatic cancer was significantly relieved one hour after the administration of 1500 mg CMT (p = 0.04). At all four time points the pain was less than baseline with CMT and at three time points greater than baseline with placebo but these results did not reach statistical significance. The summed pain intensity difference for patients was greater with CMT than with placebo, but this also did not reach significance. The incidence of volunteered side-effects was similar for both treatments. The results suggest that a nonacetylating, nonsteroidal anti-inflammatory drug may have a role complementary to that of an opioid in the management of metastatic bone pain.

  10. Helminths of foxes and other wild carnivores from rural areas in Greece.

    PubMed

    Papdopoulos, H; Himonas, C; Papazahariadou, M; Antoniadou-Sotiriadou, K

    1997-09-01

    Twenty species of helminth parasites were identified from fox, wolf, jackal and wild cat material collected in Greece. Of the 314 foxes (Vulpes vulpes) examined, 18 helminth species were recovered comprising one trematode, eight cestodes, seven nematodes and two acanthocephalans, with the cestode species Mesocestoides sp. (73.2%), Joyeuxiella echinorhynchoides (24.5%) and the nematode species Uncinaria stenocephala (43.9%), and Toxara canis (28.6%) being the most prevalent. Five cestode and three nematode species were reported from six wolves (CaniS lupus), together with one trematode, three cestode and four nematode species from five jackals (Canis aureus) and two cestode and three nematode species from four wild cats (Felis silvestris) examined. The species J. echinorhynchoides, Taenia crassiceps and Onicola canis and the genera Spirometra, Rictularia and Pachysentis are reported here for the first time in Greece. The results are discussed in the light of the feeding characteristics of wild carnivores in rural areas of Greece.

  11. Feasibility of four-dimensional preoperative simulation for elbow debridement arthroplasty.

    PubMed

    Yamamoto, Michiro; Murakami, Yukimi; Iwatsuki, Katsuyuki; Kurimoto, Shigeru; Hirata, Hitoshi

    2016-04-02

    Recent advances in imaging modalities have enabled three-dimensional preoperative simulation. A four-dimensional preoperative simulation system would be useful for debridement arthroplasty of primary degenerative elbow osteoarthritis because it would be able to detect the impingement lesions. We developed a four-dimensional simulation system by adding the anatomical axis to the three-dimensional computed tomography scan data of the affected arm in one position. Eleven patients with primary degenerative elbow osteoarthritis were included. A "two rings" method was used to calculate the flexion-extension axis of the elbow by converting the surface of the trochlea and capitellum into two rings. A four-dimensional simulation movie was created and showed the optimal range of motion and the impingement area requiring excision. To evaluate the reliability of the flexion-extension axis, interobserver and intraobserver reliabilities regarding the assessment of bony overlap volumes were calculated twice for each patient by two authors. Patients were treated by open or arthroscopic debridement arthroplasties. Pre- and postoperative examinations included elbow range of motion measurement, and completion of the patient-rated questionnaire Hand20, Japanese Orthopaedic Association-Japan Elbow Society Elbow Function Score, and the Mayo Elbow Performance Score. Measurement of the bony overlap volume showed an intraobserver intraclass correlation coefficient of 0.93 and 0.90, and an interobserver intraclass correlation coefficient of 0.94. The mean elbow flexion-extension arc significantly improved from 101° to 125°. The mean Hand20 score significantly improved from 52 to 22. The mean Japanese Orthopaedic Association-Japan Elbow Society Elbow Function Score significantly improved from 67 to 88. The mean Mayo Elbow Performance Score significantly improved from 71 to 91 at the final follow-up evaluation. We showed that four-dimensional, preoperative simulation can be generated by adding the rotation axis to the one-position, three-dimensional computed tomography image of the affected arm. This method is feasible for elbow debridement arthroplasty.

  12. Alternating Incubation Effects in the Generation of Category Exemplars

    ERIC Educational Resources Information Center

    Smith, Steven M.; Gerkens, David R.; Angello, Genna

    2017-01-01

    Four experiments tested the forgetting fixation hypothesis of incubation effects, comparing continuous vs. alternating generation of exemplars from three different types of categories. In two experiments, participants who listed as many members as possible from two different categories produced more responses, and more novel responses, when they…

  13. Effects of Two Listening Strategies for Melodic Dictation

    ERIC Educational Resources Information Center

    Buonviri, Nathan O.

    2017-01-01

    The purpose of this research was to examine effects of two listening strategies on melodic dictation scores. Fifty-four undergraduate music majors completed short tonal melodic dictations in a within-subjects design with three conditions: (a) no specified strategy in the instructions, (b) required listening before writing, and (c) required writing…

  14. Student Approaches to Learning in Relation to Online Course Completion

    ERIC Educational Resources Information Center

    Balter, Olle; Cleveland-Innes, Martha; Pettersson, Kerstin; Scheja, Max; Svedin, Maria

    2013-01-01

    This study investigates the relationship between approaches to studying and course completion in two online preparatory university courses in mathematics and computer programming. The students participating in the two courses are alike in age, gender, and approaches to learning. Four hundred and ninety-three students participating in these courses…

  15. Curriculum Development in Non-Formal Education.

    ERIC Educational Resources Information Center

    Thompson, J. D. Ekundayo

    The two parts of this book consider two main facets of nonformal curriculum development: theory and practice. Part I on nonformal curriculum theory has four chapters. Chapter 1 addresses the origins, meaning, purpose, and scope of nonformal education. Chapter 2 examines three major themes in discussions on nonformal education: nonformal education…

  16. Influences on Preservice Teacher Socialization: A Qualitative Study

    ERIC Educational Resources Information Center

    Marks, Melissa J.

    2007-01-01

    This qualitative two-year study traces the changes in beliefs and actions of four preservice teachers through the final two years of their university education program. Dialectical Theory of Socialization and Cognitive Dissonance Theory provide the theoretical framework. The findings show that three main factors affect the transfer of learning…

  17. Discriminability and Sensitivity to Reinforcer Magnitude in a Detection Task

    ERIC Educational Resources Information Center

    Alsop, Brent; Porritt, Melissa

    2006-01-01

    Three pigeons discriminated between two sample stimuli (intensities of red light). The difficulty of the discrimination was varied over four levels. At each level, the relative reinforcer magnitude for the two correct responses was varied across conditions, and the reinforcer rates were equal. Within levels, discriminability between the sample…

  18. Progress in development of male sterile germplasm for hybrid rice breeding

    USDA-ARS?s Scientific Manuscript database

    Currently, there are two types of male sterility mainly commercialized in hybrid rice production, three-line type or cytoplasmic male sterility (CMS) and two-line type or environmental male sterility (EMS). The great majority belongs to the CMS and there are four strategies that have been proven suc...

  19. Multi-layer compression: comparison of four different four-layer bandage systems applied to the leg.

    PubMed

    Dale, J J; Ruckley, C V; Gibson, B; Brown, D; Lee, A J; Prescott, R J

    2004-01-01

    To compare performance of four commercial four-layer bandage systems when applied to the leg. Four experienced bandagers applied each system: [Profore Regular (Smith and Nephew); Ultra-Four (Robinson); System 4 (Seton) and K Four (Parema)] to the same leg. Bandages were applied as single layers and as completed systems using standard techniques. For each application, 18 pressure measurements were taken using the Borgnis Medical Stocking Tester (MST) at three measuring points (ankle, gaiter and mid-calf) on medial and lateral aspects in three postures: (horizontal, standing and sitting). In all 2304 observations were made, 576 for each bandager, 576 for each bandaging system, 768 for each measuring point, 1152 for each aspect and 768 for each posture. The increase in pressure produced by each additional layer was 65-75% of the pressure of the same bandage when used as a single layer. There were significant differences in the final pressures achieved by the bandagers (means: 45-54 mmHg, p<0.001) and between bandage systems (means: System 4: 46 mmHg, Profore: 47 mmHg, K Four: 52 mmHg, Ultra-Four: 54 mmHg; p=0.005). The relationships between the final pressures achieved at each of the three measuring points, the three postures and the two aspects were not consistent among the bandage systems (p<0.01). When a bandage is applied as part of a multi-layered system it exerts approximately 70% of the pressure exerted when applied alone, thus challenging the commonly-held assumption that the final pressure achieved by a multi-layer bandaging system is the sum of the pressures exerted by each individual layer. Each of the four bandaging systems exerted different final pressures and gradients and different changes with posture change. These differences have important implications, which could influence the selection (or avoidance) of a particular bandage system according to a patient's condition and circumstances.

  20. Hypnosis and behavioral treatment in a worksite smoking cessation program.

    PubMed

    Frank, R G; Umlauf, R L; Wonderlich, S A; Ashkanazi, G S

    1986-01-01

    In the initial study, 48 subjects of the total (N = 63) ultimately used, were assigned to one of three treatments: four hypnotic sessions with a booster, two hypnotic sessions, or two hypnotic and two behavioral sessions with a booster. A follow-up group was later recruited composed of 15 subjects who received four hypnotic sessions and a booster session with less time between sessions. The results indicated no difference in smoking cessation 6 months after treatment regardless of the frequency, length between sessions, or addition of behavioral methods. Successful subjects were more educated, less able to utilize their imagination, and had fewer smokers at home.

  1. Four competing interactions for models with an uncountable set of spin values on a Cayley tree

    NASA Astrophysics Data System (ADS)

    Rozikov, U. A.; Haydarov, F. H.

    2017-06-01

    We consider models with four competing interactions ( external field, nearest neighbor, second neighbor, and three neighbors) and an uncountable set [0, 1] of spin values on the Cayley tree of order two. We reduce the problem of describing the splitting Gibbs measures of the model to the problem of analyzing solutions of a nonlinear integral equation and study some particular cases for Ising and Potts models. We also show that periodic Gibbs measures for the given models either are translation invariant or have the period two. We present examples where periodic Gibbs measures with the period two are not unique.

  2. Equivalence Class Formation in a Trace Stimulus Pairing Two-Response Format: Effects of Response Labels and Prior Programmed Transitivity Induction

    ERIC Educational Resources Information Center

    Fields, Lanny; Doran, Erica; Marroquin, Michael

    2009-01-01

    Three experiments identified factors that did and did not enhance the formation of two-node four-member equivalence classes when training and testing were conducted with trials presented in a trace stimulus pairing two-response (SP2R) format. All trials contained two separately presented stimuli. Half of the trials, called within-class trials,…

  3. [Laser Induced Fluorescence Spectroscopic Analysis of Aromatics from One Ring to Four Rings].

    PubMed

    Zhang, Peng; Liu, Hai-feng; Yue, Zong-yu; Chen, Bei-ling; Yao, Ming-fa

    2015-06-01

    In order to distinguish small aromatics preferably, a Nd : YAG Laser was used to supply an excitation laser, which was adjusted to 0.085 J x cm(-2) at 266 nm. Benzene, toluene, naphthalene, phenanthrene, anthracene, pyrene and chrysene were used as the representative of different rings aromatics. The fluorescence emission spectra were researched for each aromatic hydrocarbon and mixtures by Laser induced fluorescence (LIF). Results showed that the rings number determined the fluorescence emission spectra, and the structure with same rings number did not affect the emission fluorescence spectrum ranges. This was due to the fact that the absorption efficiency difference at 266 nm resulted in that the fluorescence intensities of each aromatic hydrocarbon with same rings number were different and the fluorescence intensities difference were more apparently with aromatic ring number increasing. When the absorption efficiency was similar at 266 nm and the concentrations of each aromatic hydrocarbon were same, the fluorescence intensities were increased with aromatic ring number increasing. With aromatic ring number increasing, the fluorescence spectrum and emission peak wavelength were all red-shifted from ultraviolet to visible and the fluorescence spectrum range was also wider as the absorption efficiency was similar. The fluorescence emission spectra from one to four rings could be discriminated in the following wavelengths, 275 to 320 nm, 320 to 375 nm, 375 to 425 nm, 425 to 556 nm, respectively. It can be used for distinguish the type of the polycyclic aromatic hydrocarbons (PAHs) as it exists in single type. As PAHs are usually exist in a variety of different rings number at the same time, the results for each aromatic hydrocarbon may not apply to the aromatic hydrocarbon mixtures. For the aromatic hydrocarbon mixtures, results showed that the one- or two-ring PAHs in mixtures could not be detected by fluorescence as three- or four-ring PAHs existed in mixture. This was caused by radiation energy transfer mechanism, in which the ultraviolet light was lost in mixtures but the fluorescence intensities were increased with the one- or two-ring PAHs adding. When the mixture only contained three- and four-ring PAHs, the fluorescence emission spectrum showed the both characteristics of three- and four-ring PAHs fluorescence. When three- and four-ring PAHs existed in mixtures at the same time, the fluorescence emission spectra were related to each concentration, so the rings number could be discriminated to a certain extent.

  4. Wear of the Primary WaveOne single file when shaping vestibular root canals of first maxillary molar

    PubMed Central

    Borie, Eduardo; Betancourt, Pablo; Aracena, Angella; Guzmán, Mario

    2017-01-01

    Background It is very important for a clinician to know the increased wear of mechanized files when establishing endodontic therapy. The aim of this study was to check the wear of the Primary WaveOne file upon shaping two, four and six maxillary molar vestibular canals. Material and Methods The deterioration of 40 files, divided into four groups, was evaluated microscopically: group 1, control (unused); group 2, two canals; group 3, four canals; and group 4, six canals. After instrumentation, the files were embedded in resin and sectioned at their apical third into three equal parts. To analyze the wear of edges in the different sections, AutoCAD software was used and analysis of variance (ANOVA) was then performed to compare the mean rake angles. Results The files with two and four uses showed slight wear, whereas those with six applications showed significant wear (p<0.05). Conclusions Primary WaveOne files can be used in up to four root canals without their edges losing effectiveness. Key words:Files wear, reciprocating motion, shaping capacity, WaveOne. PMID:28298976

  5. Wear of the Primary WaveOne single file when shaping vestibular root canals of first maxillary molar.

    PubMed

    Aracena, Daniel; Borie, Eduardo; Betancourt, Pablo; Aracena, Angella; Guzmán, Mario

    2017-03-01

    It is very important for a clinician to know the increased wear of mechanized files when establishing endodontic therapy. The aim of this study was to check the wear of the Primary WaveOne file upon shaping two, four and six maxillary molar vestibular canals. The deterioration of 40 files, divided into four groups, was evaluated microscopically: group 1, control (unused); group 2, two canals; group 3, four canals; and group 4, six canals. After instrumentation, the files were embedded in resin and sectioned at their apical third into three equal parts. To analyze the wear of edges in the different sections, AutoCAD software was used and analysis of variance (ANOVA) was then performed to compare the mean rake angles. The files with two and four uses showed slight wear, whereas those with six applications showed significant wear ( p <0.05). Primary WaveOne files can be used in up to four root canals without their edges losing effectiveness. Key words: Files wear, reciprocating motion, shaping capacity, WaveOne.

  6. Design survey of X-ray/XUV projection lithography systems

    NASA Astrophysics Data System (ADS)

    Shealy, David L.; Viswanathan, V. K.

    1991-02-01

    Several configurations of two- to four-multilayer mirror systems that have been proposed for use in soft-X-ray projection lithography are examined. The performance capabilities of spherical and aspherical two-mirror projection systems are compared, and a two-spherical-mirror four-reflection system that can resolve 0.1-micron features over a 10 x 10 mm field is described. It is emphasized that three-mirror systems show promise of high resolution in telescope applications, but have not been fully analyzed for projection lithography applications. It has been shown that a four-mirror aspheric system can be designed to meet the resolution requirements, but a trade-off must be made between reducing distortion below 10 microns over the field of view and increasing the modulation transfer function greater than 50 percent at spatial frequency of 5000 cycles/mm.

  7. Dimensionality of organizational justice in a call center context.

    PubMed

    Flint, Douglas; Haley, Lynn M; McNally, Jeffrey J

    2012-04-01

    Summary.-Employees in three call centers were surveyed about their perceptions of organizational justice. Four factors were measured: distributive justice, procedural justice, interpersonal justice, and informational justice. Structural equation modeling was employed to test whether a two-, three-, or four-factor model best fit the call center data. A three-factor model of distributive, procedural, and informational justice provided the best fit to these data. The three-factor model that showed the best fit does not conform to any of the more traditional models identified in the organizational justice literature. This implies that the context in which organizational justice is measured may play a role in identifying which justice factors are relevant to employees. Findings add to the empirical evidence on the dimensionality of organizational justice and imply that dimensionality of organizational justice is more context-dependent than previously thought.

  8. Further studies on the use of enzyme profiles to monitor residue accumulation in wildlife: Plasma enzymes in starlings fed graded concentrations of morsodren, DDE, Aroclor 1254, and malathion

    USGS Publications Warehouse

    Dieter, M.P.

    1975-01-01

    Wild-trapped starlings (Sturnus vulgaris) were fed concentrations of Morsodren (2, 4, and 8 ppm), DDE or Aroclor 1254 (5, 25, and 100 ppm), or malathion (8, 35, and 160 ppm) that were found to be sublethal in pen-reared Coturnix quail fed these amounts for 12 weeks. Plasma enzymes had to be measured earlier than planned in starlings fed Morsodren (at three weeks) or the organochlorine compounds (at seven weeks) because of unexpected, subsequent mortality. Variations in enzyme response were greater in wild than in pen-reared birds, but not enough to mask the toxicant-induced changes in enzyme activity. Cholinesterase activities decreased in birds fed Morsodren or malathion, and increased in those fed the organochlorine compounds. Lactate dehydrogenase activities increased two-fold in starlings fed Morsodren and two- to four-fold in those fed the organochlorine compounds, but only 50% in those fed malathion. Further examination of enzyme profiles showed that creatine kinase and aspartate aminotransferase activities increased two-to four-fold in birds fed Morsodren or the organochlorine compounds but not at all in those fed malathion. Thus the classes of environmental contaminants fed to starlings could be easily distinguished by these enzymatic parameters. Evaluation of enzymatic profiles appears to be a potentially valuable technique to monitor the presence of toxicants in wild populations, especially if used to complement standard chemical residue analyses. Here the residue analyses showed, after three weeks feeding, that mercury in the carcasses reflected the concentrations fed daily, whereas accumulation in the livers was two- to four-fold greater. After seven weeks feeding, liver residues of either organochlorine compound were about three-fold higher than the concentrations fed daily. However, four times as much DDE as Aroclor 1254 had accumulated in the carcasses.

  9. Population Growth and Development of the Psocid Liposcelis fusciceps (Psocoptera: Liposcelididae) at Constant Temperatures and Relative Humidities.

    PubMed

    Gautam, S G; Opit, G P; Shakya, K

    2016-02-01

    We investigated the effects of seven temperatures (22.5, 25.0, 27.5, 30.0, 32.5, 35.0, and 37.5°C) and four relative humidities (43, 55, 63, and 75%) on population growth and development of the psocid Liposcelis fusciceps Badonnel (Psocoptera: Liposcelididae). Results demonstrated that L. fusciceps did not survive at 43% RH, at all temperatures tested. At 55% RH, L. fusciceps did not survive at the highest three temperatures and no psocids survived at 37.5°C and 63% RH. The highest population growth was recorded at 30.0°C and 75% RH where populations increased 16-fold from an initial population of five females. L. fusciceps males have two to four nymphal instars, and the percentages of males with two, three, and four instars were 28, 70, and 2%, respectively. Female L. fusciceps have two to five instars, and the percentages of females with two, three, four, and five instars were 2, 33, 63, and 2%, respectively. The total developmental time for males was shorter than females. We developed temperature-dependent development equations for male and female eggs, individual nymphal, combined nymphal, and combined immature stages. Based on 30-d population growth, L. fusciceps can survive and multiply at a relative humidity of 55% at 22.5-30.0°C, but does better at 27.5-32.5°C and a higher relative humidity of 75%. Relative humidities of ≤ 63% and temperatures of ≥ 32.5°C are detrimental to L. fusciceps. These data provide a better understanding of L. fusciceps population dynamics and can be used to develop effective management strategies for this psocid. © The Authors 2015. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  10. Endwall flows and blading design for axial flow compressors

    NASA Astrophysics Data System (ADS)

    Robinson, Christopher J.

    Literature relevant to blading design in the endwall region is reviewed, and important three dimensional flow phenomena occurring in embedded stages of axial compressors are described. A low speed axial flow four stage compressor rig is described and bladings studied are detailed: two conventional and two with end bends. The application of a three dimensional Navier-Stokes solver to the bladings' stators, to assess the effectiveness of the code, is reported. Calculation results of exit whirl angles, losses, and surface static pressures are compared with experiment.

  11. Molecular phylogenetics of the gomphoid-phalloid fungi with an establishment of the new subclass Phallomycetidae and two new orders

    Treesearch

    Kentaro Hosaka; Scott T. Bates; Ross E. Beever; Michael A. Castellano; Wesley Colgan; Laura S. Dominguez; Eduardo R. Nouhra; Jozsef Geml; Admir J. Giachini; S. Ray Kenney; Nicholas B. Simpson; Joseph W. Spatafora; James M. Trappe

    2006-01-01

    Molecular phylogenetic analyses for the gomphoid-phalloid fungi were conducted based on the five gene dataset with extensive taxon sampling. The monophyly of the gomphoid-phalloid clade was strongly supported, and four well supported major subclades were recognized. Three of the four subclades were represented entirely by gastroid taxa, and only Gomphales contained...

  12. Responding Behaviors. Grade Three. One in a Series of Career Development Curriculum Units for the Elementary Classroom. (Second Edition).

    ERIC Educational Resources Information Center

    Anderson, Karen; Tutton, Joyce

    Focusing on self awareness (emotional and social), this unit entitled "Responding Behavior" is one of four grade 3 units which are part of a total set of twenty-seven career development curriculum units for grades K-6. This unit is organized into four sections. Section 1 identifies two career development-centered curriculum (CDCC)…

  13. Comparison between all-on-four and all-on-six treatment concepts and framework material on stress distribution in atrophic maxilla: A prototyping guided 3D-FEA study.

    PubMed

    Bhering, Cláudia Lopes Brilhante; Mesquita, Marcelo Ferraz; Kemmoku, Daniel Takanori; Noritomi, Pedro Yoshito; Consani, Rafael Leonardo Xediek; Barão, Valentim Adelino Ricardo

    2016-12-01

    We evaluated two treatment concepts for the rehabilitation of moderate atrophic maxilla with dental implants (all-on-four and all-on-six) and the effect of framework material on the stress distribution of implant-support system. A three-dimensional finite element model based on a prototype was built to simulate an entirely edentulous maxilla with moderate sinus pneumatization that was rehabilitated with a full-arch fixed dental prosthesis. Four standard implants were positioned according to the all-on-four concept and four standard implants and two short implants were placed according to the all-on-six concept. Three framework materials were evaluated: cobalt-chrome (CoCr), titanium (Ti) and zirconia (Zr), totalizing six groups. A unilateral oblique force of 150N was applied to the posterior teeth. The von Mises (σVM), maximum (σmax) and minimum (σmin) principal stress and displacements were obtained. All-on-six showed smaller σmin, σVM and σmax values on the cortical bone, implants and trabecular bone, respectively. All-on-four exhibited higher displacement levels. Ti presented the highest stress values on the cortical bone, implants, abutments, prosthetic screws and displacement levels. In conclusion, the all-on-six approach and framework stiffer materials showed the most favorable biomechanical behavior. However, the stress values did not exceed the bone resistance limits for both treatment concepts. Copyright © 2016 Elsevier B.V. All rights reserved.

  14. Evaluation of limited sampling models for prediction of oral midazolam AUC for CYP3A phenotyping and drug interaction studies.

    PubMed

    Mueller, Silke C; Drewelow, Bernd

    2013-05-01

    The area under the concentration-time curve (AUC) after oral midazolam administration is commonly used for cytochrome P450 (CYP) 3A phenotyping studies. The aim of this investigation was to evaluate a limited sampling strategy for the prediction of AUC with oral midazolam. A total of 288 concentration-time profiles from 123 healthy volunteers who participated in four previously performed drug interaction studies with intense sampling after a single oral dose of 7.5 mg midazolam were available for evaluation. Of these, 45 profiles served for model building, which was performed by stepwise multiple linear regression, and the remaining 243 datasets served for validation. Mean prediction error (MPE), mean absolute error (MAE) and root mean squared error (RMSE) were calculated to determine bias and precision The one- to four-sampling point models with the best coefficient of correlation were the one-sampling point model (8 h; r (2) = 0.84), the two-sampling point model (0.5 and 8 h; r (2) = 0.93), the three-sampling point model (0.5, 2, and 8 h; r (2) = 0.96), and the four-sampling point model (0.5,1, 2, and 8 h; r (2) = 0.97). However, the one- and two-sampling point models were unable to predict the midazolam AUC due to unacceptable bias and precision. Only the four-sampling point model predicted the very low and very high midazolam AUC of the validation dataset with acceptable precision and bias. The four-sampling point model was also able to predict the geometric mean ratio of the treatment phase over the baseline (with 90 % confidence interval) results of three drug interaction studies in the categories of strong, moderate, and mild induction, as well as no interaction. A four-sampling point limited sampling strategy to predict the oral midazolam AUC for CYP3A phenotyping is proposed. The one-, two- and three-sampling point models were not able to predict midazolam AUC accurately.

  15. Different mechanisms are involved in the transcriptional activation by yeast heat shock transcription factor through two different types of heat shock elements.

    PubMed

    Hashikawa, Naoya; Yamamoto, Noritaka; Sakurai, Hiroshi

    2007-04-06

    The hydrophobic repeat is a conserved structural motif of eukaryotic heat shock transcription factor (HSF) that enables HSF to form a homotrimer. Homotrimeric HSF binds to heat shock elements (HSEs) consisting of three inverted repeats of the sequence nGAAn. Sequences consisting of four or more nGAAn units are bound cooperatively by two HSF trimers. We show that in Saccharomyces cerevisiae cells oligomerization-defective Hsf1 is not able to bind HSEs with three units and is not extensively phosphorylated in response to stress; it is therefore unable to activate genes containing this type of HSE. Several lines of evidence indicate that oligomerization is a prerequisite for stress-induced hyperphosphorylation of Hsf1. In contrast, oligomerization and hyperphosphorylation are not necessary for gene activation via HSEs with four units. Intragenic suppressor screening of oligomerization-defective hsf1 showed that an interface between adjacent DNA-binding domains is important for the binding of Hsf1 to the HSE. We suggest that Saccharomyces cerevisiae HSEs with different structures are regulated differently; HSEs with three units require Hsf1 to be both oligomerized and hyperphosphorylated, whereas HSEs with four or more units do not require either.

  16. Mismatch of Posttraumatic Stress Disorder (PTSD) Symptoms and DSM-IV Symptom Clusters in a Cancer Sample: Exploratory Factor Analysis of the PTSD Checklist-Civilian Version

    PubMed Central

    Shelby, Rebecca A.; Golden-Kreutz, Deanna M.; Andersen, Barbara L.

    2007-01-01

    The Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV; American Psychiatric Association, 1994a) conceptualization of posttraumatic stress disorder (PTSD) includes three symptom clusters: reexperiencing, avoidance/numbing, and arousal. The PTSD Checklist-Civilian Version (PCL-C) corresponds to the DSM-IV PTSD symptoms. In the current study, we conducted exploratory factor analysis (EFA) of the PCL-C with two aims: (a) to examine whether the PCL-C evidenced the three-factor solution implied by the DSM-IV symptom clusters, and (b) to identify a factor solution for the PCL-C in a cancer sample. Women (N = 148) with Stage II or III breast cancer completed the PCL-C after completion of cancer treatment. We extracted two-, three-, four-, and five-factor solutions using EFA. Our data did not support the DSM-IV PTSD symptom clusters. Instead, EFA identified a four-factor solution including reexperiencing, avoidance, numbing, and arousal factors. Four symptom items, which may be confounded with illness and cancer treatment-related symptoms, exhibited poor factor loadings. Using these symptom items in cancer samples may lead to overdiagnosis of PTSD and inflated rates of PTSD symptoms. PMID:16281232

  17. An integrated approach to reservoir modeling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Donaldson, K.

    1993-08-01

    The purpose of this research is to evaluate the usefulness of the following procedural and analytical methods in investigating the heterogeneity of the oil reserve for the Mississipian Big Injun Sandstone of the Granny Creek field, Clay and Roane counties, West Virginia: (1) relational database, (2) two-dimensional cross sections, (3) true three-dimensional modeling, (4) geohistory analysis, (5) a rule-based expert system, and (6) geographical information systems. The large data set could not be effectively integrated and interpreted without this approach. A relational database was designed to fully integrate three- and four-dimensional data. The database provides an effective means for maintainingmore » and manipulating the data. A two-dimensional cross section program was designed to correlate stratigraphy, depositional environments, porosity, permeability, and petrographic data. This flexible design allows for additional four-dimensional data. Dynamic Graphics[sup [trademark

  18. Analysis the Effectiveness of Three Online Vocabulary Flashcard Websites on L2 Learners' Level of Lexical Knowledge

    ERIC Educational Resources Information Center

    Chien, Chin-Wen

    2015-01-01

    This study compared and contrasted 64 Taiwanese college freshmen's perceptions of and attitudes toward three online vocabulary flashcard websites, Quizlet, Study Stack, and Flashcard Exchange. Four types of data were collected in two freshmen English classes in a university in Taiwan from February to April 2013. Data included online flashcard…

  19. The Effects of Talking-Head with Various Realism Levels on Students' Emotions in Learning

    ERIC Educational Resources Information Center

    Mohamad Ali, Ahmad Zamzuri; Hamdan, Mohd Najib

    2017-01-01

    The aim of this study was to evaluate the effects of various realistic levels of talking-head on students' emotions in pronunciation learning. Four talking-head characters with varying levels of realism were developed and tested: a nonrealistic three-dimensional character, a realistic three-dimensional character, a two-dimensional character, and…

  20. High School Student's Perceptions of Geography: A Phenomenological Study

    ERIC Educational Resources Information Center

    Roberson, Dwayne D.

    2017-01-01

    The purpose of this study was to explore the experiences of high school students' perceptions of their Geography course in a Southeast Texas high school. Five focus groups of students were assembled (seventeen students in two groups of four and three groups of three participants) and asked a series of six questions relating to the different…

  1. Speaking with a Single Cerebral Hemisphere: fMRI Language Organization after Hemispherectomy in Childhood

    ERIC Educational Resources Information Center

    Liegeois, Frederique; Connelly, Alan; Baldeweg, Torsten; Vargha-Khadem, Faraneh

    2008-01-01

    Speech-related fMRI activation was examined in six hemispherectomy patients (three left LX, three right RX, four with congenital and two with late-acquired hemiplegia) operated in childhood for the relief of drug-resistant epilepsy. Although the temporal and sensorimotor pattern of activation was similar to that found in neurologically intact…

  2. Variations in University Students' Scientific Reasoning Skills across Majors, Years, and Types of Institutions

    ERIC Educational Resources Information Center

    Ding, Lin; Wei, Xin; Liu, Xiufeng

    2016-01-01

    This study investigates three aspects--university major, year, and institution type--in relation to student scientific reasoning. Students from three majors (science, engineering, and education), four year levels (years 1 through 4), and two tiers of Chinese universities (tiers 1 and 2) participated in the study. A large-scale written assessment…

  3. Tumours around the foramen of Monro: clinical and neuroimaging features and their differential diagnosis.

    PubMed

    Nishio, Shunji; Morioka, Takato; Suzuki, Satoshi; Fukui, Masashi

    2002-03-01

    The clinical and neuroimaging features of 20 patients with lateral ventricular tumours located around the foramen of Monro were reviewed retrospectively with special emphasis on the differential diagnoses. Histologic types were: eight neurocytomas, four subependymal giant cell astrocytomas (SGCAs), three subependymomas, two fibrillary astrocytomas, and one each of pilocytic astrocytoma, malignant astrocytoma and malignant teratoma. The mean age of the patients with neurocytoma was 29.6 years, with SGCA 13.3 years and with subependymoma 55.3 years. All tumours appeared nodular in shape, and on computed tomography (CT) neurocytomas were either isodense or highdense with the brain, while all subependymomas and SGCAs were lowdense. Calcification was observed in two SGCAs, and one neurocytoma. Five neurocytomas and all four SGCAs showed mild to moderate contrast enhancement, while all three subependymomas showed either no, or scarce, enhancement. Magnetic resonance imaging (MRI) studies were available in 10 patients, with the signal characteristics of four neurocytomas and three SGCAs being nonspecific, while two subependymomas were both hypointense on T1-weighted images and hyperintense on T2-weighted images. Thus important features for differential diagnosis included age of the patient and density on precontrast CT. In this series, either an extensive excision of the tumour or a partial removal, thus relieving the obstruction of the foramina of Monro, usually provided long term survival, with 18 patients surviving a mean of 10.8 years. Copyright 2002, Elsevier Science Ltd. All rights reserved.

  4. An application of belief-importance theory in the domain of academic achievement.

    PubMed

    Petrides, K V; Frederickson, Norah

    2011-03-01

    BACKGROUND. Belief-importance (belimp; Petrides, 2010a,b) theory posits that personality traits confer on the individual a propensity to perceive convergences and divergences between their belief that they can attain goals and the importance that they place on these goals. The theory suggests that these convergences and divergences have important implications for affect, motivation, and action. AIMS. To test belimp theory using performance-based criteria relating to academic achievement and constructs from the personality domain. SAMPLES. Two hundred and forty-two students, of whom 121 were male and 117 were female (4 unreported). They were approximately 18 years old at the time of testing. METHODS. Data were collected on the belief and importance of academic achievement, the Giant Three personality dimensions, and trait emotional intelligence (trait EI). Academic achievement was operationalized via Key Stage 3 and A-level assessment results. RESULTS. Four hypotheses concerning academic achievement were tested and confirmed, with the Motivation quadrant scoring higher than the other three belimp quadrants (Hubris, Depression, and Apathy). Four hypotheses concerning personality were tested, of which two were confirmed, with the Hubris quadrant scoring highest on psychoticism and the Depression quadrant scoring highest on neuroticism. Four hierarchical regressions demonstrated the incremental validity of the belief and importance belimp coordinates over the Giant Three personality dimensions in the prediction of academic achievement. CONCLUSIONS. The results are encouraging for belimp theory and complement similarly supportive findings in Petrides (2010b,c). ©2010 The British Psychological Society.

  5. Population genetic structure of the African elephant in Uganda based on variation at mitochondrial and nuclear loci: evidence for male-biased gene flow.

    PubMed

    Nyakaana, S; Arctander, P

    1999-07-01

    A drastic decline has occurred in the size of the Uganda elephant population in the last 40 years, exacerbated by two main factors; an increase in the size of the human population and poaching for ivory. One of the attendant consequences of such a decline is a reduction in the amount of genetic diversity in the surviving populations due to increased effects of random genetic drift. Information about the amount of genetic variation within and between the remaining populations is vital for their future conservation and management. The genetic structure of the African elephant in Uganda was examined using nucleotide variation of mitochondrial control region sequences and four nuclear microsatellite loci in 72 individuals from three localities. Eleven mitochondrial DNA (mtDNA) haplotypes were observed, nine of which were geographically localized. We found significant genetic differentiation between the three populations at the mitochondrial locus while three out of the four microsatellite loci differentiated KV and QE, one locus differentiated KV and MF and no loci differentiated MF and QE. Expected heterozygosity at the four loci varied between 0.51 and 0.84 while nucleotide diversity at the mitochondrial locus was 1.4%. Incongruent patterns of genetic variation within and between populations were revealed by the two genetic systems, and we have explained these in terms of the differences in the effective population sizes of the two genomes and male-biased gene flow between populations.

  6. The Ottawa panel clinical practice guidelines for the management of knee osteoarthritis. Part two: strengthening exercise programs.

    PubMed

    Brosseau, Lucie; Taki, Jade; Desjardins, Brigit; Thevenot, Odette; Fransen, Marlene; Wells, George A; Mizusaki Imoto, Aline; Toupin-April, Karine; Westby, Marie; Álvarez Gallardo, Inmaculada C; Gifford, Wendy; Laferrière, Lucie; Rahman, Prinon; Loew, Laurianne; De Angelis, Gino; Cavallo, Sabrina; Shallwani, Shirin Mehdi; Aburub, Ala'; Bennell, Kim L; Van der Esch, Martin; Simic, Milena; McConnell, Sara; Harmer, Alison; Kenny, Glen P; Paterson, Gail; Regnaux, Jean-Philippe; Lefevre-Colau, Marie-Martine; McLean, Linda

    2017-05-01

    To identify effective strengthening exercise programs and provide rehabilitation teams and patients with updated, high-quality recommendations concerning traditional land-based exercises for knee osteoarthritis. A systematic search and adapted selection criteria included comparative controlled trials with strengthening exercise programs for patients with knee osteoarthritis. A panel of experts reached consensus on the recommendations using a Delphi survey. A hierarchical alphabetical grading system (A, B, C+, C, D, D+ or D-) was based on statistical significance ( p < 0.5) and clinical importance (⩾15% improvement). The 26 high-quality studies identified demonstrated that various strengthening exercise programs with/without other types of therapeutic exercises are generally effective for improving knee osteoarthritis management within a six-month period. Strengthening exercise programs demonstrated a significant improvement for pain relief (four Grade A, ten Grade B, two Grade C+), physical function (four Grade A, eight Grade B) and quality of life (three Grade B). Strengthening in combination with other types of exercises (coordination, balance, functional) showed a significant improvement in pain relief (three Grade A, 11 Grade B, eight Grade C+), physical function (two Grade A, four Grade B, three Grade C+) and quality of life (one Grade A, one Grade C+). There are a variety of choices for strengthening exercise programs with positive recommendations for healthcare professionals and knee osteoarthritis patients. There is a need to develop combined behavioral and muscle-strengthening strategies to improve long-term maintenance of regular strengthening exercise programs.

  7. Fixed or mixed: a comparison of three, four and mixed-option multiple-choice tests in a Fetal Surveillance Education Program

    PubMed Central

    2013-01-01

    Background Despite the widespread use of multiple-choice assessments in medical education assessment, current practice and published advice concerning the number of response options remains equivocal. This article describes an empirical study contrasting the quality of three 60 item multiple-choice test forms within the Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG) Fetal Surveillance Education Program (FSEP). The three forms are described below. Methods The first form featured four response options per item. The second form featured three response options, having removed the least functioning option from each item in the four-option counterpart. The third test form was constructed by retaining the best performing version of each item from the first two test forms. It contained both three and four option items. Results Psychometric and educational factors were taken into account in formulating an approach to test construction for the FSEP. The four-option test performed better than the three-option test overall, but some items were improved by the removal of options. The mixed-option test demonstrated better measurement properties than the fixed-option tests, and has become the preferred test format in the FSEP program. The criteria used were reliability, errors of measurement and fit to the item response model. Conclusions The position taken is that decisions about the number of response options be made at the item level, with plausible options being added to complete each item on both psychometric and educational grounds rather than complying with a uniform policy. The point is to construct the better performing item in providing the best psychometric and educational information. PMID:23453056

  8. Fixed or mixed: a comparison of three, four and mixed-option multiple-choice tests in a Fetal Surveillance Education Program.

    PubMed

    Zoanetti, Nathan; Beaves, Mark; Griffin, Patrick; Wallace, Euan M

    2013-03-04

    Despite the widespread use of multiple-choice assessments in medical education assessment, current practice and published advice concerning the number of response options remains equivocal. This article describes an empirical study contrasting the quality of three 60 item multiple-choice test forms within the Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG) Fetal Surveillance Education Program (FSEP). The three forms are described below. The first form featured four response options per item. The second form featured three response options, having removed the least functioning option from each item in the four-option counterpart. The third test form was constructed by retaining the best performing version of each item from the first two test forms. It contained both three and four option items. Psychometric and educational factors were taken into account in formulating an approach to test construction for the FSEP. The four-option test performed better than the three-option test overall, but some items were improved by the removal of options. The mixed-option test demonstrated better measurement properties than the fixed-option tests, and has become the preferred test format in the FSEP program. The criteria used were reliability, errors of measurement and fit to the item response model. The position taken is that decisions about the number of response options be made at the item level, with plausible options being added to complete each item on both psychometric and educational grounds rather than complying with a uniform policy. The point is to construct the better performing item in providing the best psychometric and educational information.

  9. Legionnaire's disease: a nosocomial outbreak in Turkey.

    PubMed

    Ozerol, I H; Bayraktar, M; Cizmeci, Z; Durmaz, R; Akbas, E; Yildirim, Z; Yologlu, S

    2006-01-01

    Six nosocomial cases of Legionella pneumophila occurred over a two-week period, with one further case being diagnosed retrospectively after 30 days. Strains isolated from the hospital water system were clonally related to a single sputum isolate. A sero-epidemiological investigation into legionella exposure amongst staff and inpatients was undertaken at the eight-year-old Inonu University Medical Centre in Turkey, which has 600 beds and central air conditioning. There is no disinfection programme for the hospital water system. A total of 500 serum samples (400 hospital staff and 100 inpatients) were screened for antibody to L. pneumophila by enzyme-linked immunosorbent assay (ELISA). Seroreactive cases were confirmed by a four-fold antibody rise in ELISA, a high indirect immunofluorescent assay (IFA) antibody titre or a positive urinary antigen test. ELISA showed that 24 (6%) of the 400 hospital staff and seven (7%) of the 100 inpatients had antibody titres higher than the cut-off value. ELISA-seroreactive cases were followed for two to four weeks. Of these subjects, seven (three patients and four staff) showed a four-fold rise in antibody titre by ELISA, six (three patients and three staff) had a high IFA titre, three patients with pneumonia had a positive urinary antigen test, and one of these patients also had a positive sputum culture. In addition, 22 water distribution systems were screened for the presence of L. pneumophila by culture. L. pneumophila was isolated from 15 sites. Pulsed-field gel electrophoresis typing indicated that all strains isolated from water systems were identical and clonally related to the strain isolated from sputum. Superheating and flushing of water systems were undertaken with legionella being re-isolated from four sites. Repeated superheating and flushing eliminated legionella completely. This study demonstrated that rapid detection of L. pneumophila and adequate superheating and flushing of water systems are effective for elimination and reduction of spread of this organism.

  10. Three-dimensional supersonic flow around double compression ramp with finite span

    NASA Astrophysics Data System (ADS)

    Lee, H. S.; Lee, J. H.; Park, G.; Park, S. H.; Byun, Y. H.

    2017-01-01

    Three-dimensional flows of Mach number 3 around a double-compression ramp with finite span have been investigated numerically. Shadowgraph visualisation images obtained in a supersonic wind tunnel are used for comparison. A three-dimensional Reynolds-averaged Navier-Stokes solver was used to obtain steady numerical solutions. Two-dimensional numerical results are also compared. Four different cases were studied: two different second ramp angles of 30° and 45° in configurations with and without sidewalls, respectively. Results showed that there is a leakage of mass and momentum fluxes heading outwards in the spanwise direction for three-dimensional cases without sidewalls. The leakage changed the flow characteristics of the shock-induced boundary layer and resulted in the discrepancy between the experimental data and two-dimensional numerical results. It is found that suppressing the flow leakage by attaching the sidewalls enhances the two-dimensionality of the experimental data for the double-compression ramp flow.

  11. One-, two-, and three-class resistance among HIV-infected patients on antiretroviral therapy in private care clinics: Mumbai, India.

    PubMed

    Gupta, Amita; Saple, Dattaray G; Nadkarni, Girish; Shah, Bijal; Vaidya, Satish; Hingankar, Nitin; Chaturbhuj, Devidas; Deshmukh, Praveen; Walshe, Louise; Hudelson, Sarah E; James, Maria; Paranjape, Ramesh S; Eshleman, Susan H; Tripathy, Srikanth

    2010-01-01

    HIV-infected patients receiving antiretroviral (ARV) therapy (ART) in India are not all adequately virally suppressed. We analyzed ARV drug resistance in adults receiving ART in three private clinics in Mumbai, India. HIV viral load was measured in 200 patients with the Roche AMPLICOR HIV-1 Monitor Test, v1.5. HIV genotyping was performed with the ViroSeq HIV-1 Genotyping System for 61 participants who had HIV-1 RNA >1000 copies/ml. Genotyping results were obtained for 51 samples. The participants with resistance results were on ART for a median of 24 months and were on their current regimen for a median of 12 months (median CD4 cell count: 217 cells/mm(3); median HIV viral load: 28,200 copies/ml). ARV regimens included nonnucleoside reverse transcriptase inhibitor (NNRTI)-based regimens (n = 27), dual nucleoside reverse transcriptase inhibitors (NRTIs, n = 19), protease inhibitor (PI)-based regimens (n = 3), and other regimens (n = 2). Twenty-six participants (51.0%) were on their first ARV regimen and 24 (47%) reported >95% adherence. Forty-nine participants (96.1%) had resistance to at least one ARV drug; 47 (92.2%) had NRTI resistance, 32 (62.7%) had NNRTI resistance, and four (7.8%) had PI resistance. Thirty (58.8%) had two-class resistance and three (5.9%) had three-class resistance. Four (8%) had three or more resistance mutations associated with etravirine resistance and two (4%) had two mutations associated with reduced darunavir susceptibility. Almost all patients with HIV-1 RNA >1000 copies/ml had NRTI resistance and nearly two-thirds had NNRTI resistance; PI resistance was uncommon. Nearly 60% and 6% had two- and three-class resistance, respectively. This emphasizes the need for greater viral load and resistance monitoring, use of optimal ART combinations, and increased availability of second- and third-line agents for patients with ARV resistance.

  12. Conjoined twins: morphogenesis of the heart and a review.

    PubMed

    Gilbert-Barness, Enid; Debich-Spicer, Diane; Opitz, John M

    2003-08-01

    Five cases of conjoined twins have been studied. These included three thoracopagus twins, one monocephalus diprosopus (prosop = face), and one dicephalus dipus dibrachus. The thoracopagus twins were conjoined only from the upper thorax to the umbilicus with a normal foregut. These three cases shared a single complex multiventricular heart, one with a four chambered heart with one atrium and one ventricle belonging to each twin with complex venous and arterial connection; two had a seven chambered heart with four atria and three ventricles. The mono-cephalus diprosopus twins had a single heart with tetralogy of Fallot. The dicephalus twins had two separate axial skeletons to the sacrum, two separate hearts were connected between the right atria with a shared inferior vena cava. Thoracopagus twinning is associated with complex cardiac malformations. The cardiac anlagen in cephalopagus or diprosopus are diverted and divided along with the entire rostral end of the embryonic disc and result in two relatively normal shared hearts. However, in thoracopagus twins the single heart is multiventricular and suggests very early union with fusion of the cardiac anlagen before significant differentiation. Cardiac morphogenesis in conjoined twins therefore appears to depend on the site of the conjoined fusion and the temporal and spatial influence that determines morphogenesis as well as abnormally oriented embryonic axes. Copyright 2003 Wiley-Liss, Inc.

  13. Impact of SCBA size and fatigue from different firefighting work cycles on firefighter gait.

    PubMed

    Kesler, Richard M; Bradley, Faith F; Deetjen, Grace S; Angelini, Michael J; Petrucci, Matthew N; Rosengren, Karl S; Horn, Gavin P; Hsiao-Wecksler, Elizabeth T

    2018-04-04

    Risk of slips, trips and falls in firefighters maybe influenced by the firefighter's equipment and duration of firefighting. This study examined the impact of a four self-contained breathing apparatus (SCBA) three SCBA of increasing size and a prototype design and three work cycles one bout (1B), two bouts with a five-minute break (2B) and two bouts back-to-back (BB) on gait in 30 firefighters. Five gait parameters (double support time, single support time, stride length, step width and stride velocity) were examined pre- and post-firefighting activity. The two largest SCBA resulted in longer double support times relative to the smallest SCBA. Multiple bouts of firefighting activity resulted in increased single and double support time and decreased stride length, step width and stride velocity. These results suggest that with larger SCBA or longer durations of activity, firefighters may adopt more conservative gait patterns to minimise fall risk. Practitioner Summary: The effects of four self-contained breathing apparatus (SCBA) and three work cycles on five gait parameters were examined pre- and post-firefighting activity. Both SCBA size and work cycle affected gait. The two largest SCBA resulted in longer double support times. Multiple bouts of activity resulted in more conservative gait patterns.

  14. HELIOS dual swept frequency radiometer

    NASA Technical Reports Server (NTRS)

    White, J. R.

    1975-01-01

    The HELIOS dual swept frequency radiometer, used in conjunction with a dipole antenna, was designed to measure electromagnetic radiation in space. An engineering prototype was fabricated and tested on the HELIOS spacecraft. Two prototypes and two flight units were fabricated and three of the four units were integrated into the HELIOS spacecraft. Two sets of ground support equipment were provided for checkout of the radiometer.

  15. Using the Community College to Control College Costs: How Much Cheaper Is It?

    ERIC Educational Resources Information Center

    Romano, Richard M.; Djajalaksana, Yenni M.

    2011-01-01

    Data from NCES indicate that it is two to three times more expensive to educate a student at a public four-year college than at a community college. These figures exaggerate the difference between the two when you calculate the costs of the first two years of education for students working on a bachelor's degree. Using modified Integrated…

  16. Coherent and phase-sensitive phenomena of ultrashort laser pulses propagating in three-level {lambda}-type systems studied with the finite-difference time-domain method

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Loiko, Yurii; Institute of Molecular and Atomic Physics, National Academy of Sciences of Belarus, Nezaleznasty Ave. 70, 220072 Minsk; Serrat, Carles

    2006-06-15

    Propagation of single- and two-color hyperbolic secant femtosecond laser pulses in a three-level {lambda}-type quantum system is investigated by solving the Maxwell and density matrix equations with the finite-difference time-domain and Runge-Kutta methods. As a first study of our modeling, we simulate pulse self-induced transparency (SIT) in two-level systems and see how this phenomenon can be controlled by manipulating the initial relative phase between the SIT pulse and a second control pulse, provided the ratio between both pulse frequencies obeys the relation {omega}{sub 1}/{omega}{sub 2}=3. We then examine frequency down-conversion processes that are observed with single- and two-color pulses themore » envelope area of which is equal to or a multiple of 2{pi}, for pulse frequencies close to resonance with the transitions of a three-level {lambda} medium. Also, phase-sensitive phenomena are discussed in the case of two-color {omega}-3{omega} pulses propagating resonantly in the three-level system. In particular, possibilities for such coherent control are found for frequency down-conversion processes when the ratio of the frequencies of optical transitions is {omega}{sub 13}/{omega}{sub 12}=3. The conditions for quantum control of four-wave mixing processes are also examined when the pulse frequencies of two-color {omega}-3{omega} pulses are far from any resonance of the three-level system. We demonstrate the possibility to cancel the phase sensitivity of the four-wave coupling in a {lambda}-type system by competition effects between optical transitions.« less

  17. New Coleoptera records from New Brunswick, Canada: Anthribidae, Brentidae, Dryophthoridae, Brachyceridae, and Curculionidae, with additions to the fauna of Quebec, Nova Scotia and Prince Edward Island

    PubMed Central

    Webster, Reginald P.; Anderson, Robert S.; Sweeney, Jon D.; DeMerchant, Ian

    2012-01-01

    Abstract We report 63 species of Curculionoidea that are new to New Brunswick (three species of Anthribidae, four species of Brentidae, three species of Dryophthoridae, three species of Brachyceridae, 50 species of Curculionidae). Among these are 27 species (two Anthribidae, two Brenthidae, one Brachyceridae, 22 Curculionidae) that are also newly recorded for the Maritime provinces, and one species, Plesiobaris disjuncta Casey (Curculionidae) that is newly recorded for Canada from New Brunswick and Quebec. Bagous planatus LeConte is reinstated to the faunal list of New Brunswick. Two species of Curculionidae are newly recorded from Nova Scotia and the Maritime provinces, and two others are reported for the first time for Prince Edward Island. PMID:22539901

  18. Effect of changes to the manufacturer application techniques 
on the shear bond strength of simplified dental adhesives.

    PubMed

    Chasqueira, Ana Filipa; Arantes-Oliveira, Sofia; Portugal, Jaime

    2013-09-13

    The aim of this work was to assess the shear bond strength (SBS) between a composite resin and dentin, promoted by two dental adhesive systems (one-step self-etching adhesive Easy Bond [3M ESPE], and two-step etch-and-rinse adhesive Scotchbond 1XT [3M ESPE]) with different application protocols (per manufacturer's instruction (control group); with one to four additional adhesive layers; or with an extra hydrophobic adhesive layer). Proximal enamel was removed from ninety caries-free human molars to obtain two dentin discs per tooth, which were randomly assigned to twelve experimental groups (n=15). After adhesion protocol, the composite resin (Filtek Z250 [3M ESPE]) was applied. Specimens were mounted in the Watanabe test device and shear bond test was performed in a universal testing machine with a crosshead speed of 5 mm/min. Data were analyzed with ANOVA followed by Student-Newman-Keuls tests (P<0.05). The highest SBS mean value was attained with the Easy Bond three layers group (41.23±2.71 MPa) and the lowest with Scotchbond 1XT per manufacturer's instructions (27.15±2.99 MPa). Easy Bond yielded higher SBS values than Scotchbond 1XT. There were no statistically significant differences (P>0.05) between the application protocols tested, except for the three and four layers groups, that presented higher SBS results compared to manufacturer's instruction groups (P<0.05). No statistically significant differences were detected between the three and four layers groups (P≥0.05). It is recommendable to apply three adhesive layers when using Easy Bond and Scotchbond 1XT adhesives, since it improves SBS values without consuming much time.

  19. Additive effect of ketoconazole and octreotide in the treatment of severe adrenocorticotropin-dependent hypercortisolism.

    PubMed

    Vignati, F; Loli, P

    1996-08-01

    Over the last few years ketoconazole and octreotide have been employed in the treatment of pituitary-dependent or ectopic Cushing's syndrome. In four patients (two men and two women, aged 25-64 yr) with severe ACTH-dependent hypercortisolism in whom medical treatment with ketoconazole showed limited effectiveness and/or tolerability, we tried the association with octreotide. In all patients ketoconazole (200-1000 mg) induced a marked decrease in urinary free cortisol (UFC) excretion, but normalization could not be achieved. After ketoconazole discontinuation, three patients received octreotide alone (300-1500 micrograms/day, sc). This drug caused a dramatic decrease in UFC excretion, although not normalization; in all patients, escape from treatment occurred. Combined treatment was carried out for 10-180 days. Urinary cortisol excretion normalized and remained steadily within normal limits in three of four patients in whom normal UFC excretion had never been attained with both single drug regimens; in the fourth patient, UFC excretion decreased to levels lower than those achieved with ketoconazole or octreotide alone. The association with octreotide allowed a reduction in the daily dose of ketoconazole in three patients. Consistent with the steady reduction of cortisol production, a striking clinical improvement occurred in all patients after starting combined treatment. The normalization of UFC in three of four patients treated with both agents suggests that this approach may be useful in the long term treatment of severe forms of hypercortisolism of both pituitary and ectopic origin. In contrast to the limited effectiveness of each drug taken singularly at the same or higher doses, the association of the two drugs had an additive effect in the attainment of normal urinary cortisol excretion.

  20. [Asthma caused by Lucilia Caesar larvae: clinical and immunologic study].

    PubMed

    Siracusa, A; Verga, A; Bacoccoli, R; Fabbri, A; Felicioni, D

    1989-01-01

    Lucilia Caesar larvae (LCL) are used as live fish bait by anglers. Five cases of asthma and rhinoconjunctivitis following exposure to LCL are reported. Three had work-related asthma as they were working on a fish bait farm or shop and two had asthma when they went fishing. In one subject exposure to LCL caused asthma, rhinoconjunctivitis and contact urticaria. In four subjects peak expiratory flow rate (PEFR) was monitored during exposure to LCL. In three out of four subjects there was evidence of LCL-related asthma. In one subject it was not possible to record PEFR during exposure to LCL, as he had not gone fishing since 1985. Two extracts of LCL were prepared: one was the PBS (phosphate-buffered saline) washing fluid of LCL, the other was the PBS extract of homogenized LCL. Positive cutaneous prick tests to both LCL extracts were detected in three out of four symptomatic subjects. Specific IgE against both LCL extract antigens were found by the RAST method in four out of five subjects with LCL-related asthma. One subject had both negative skin tests and RAST. Specificity and potency of LCL-IgE binding was shown by RAST inhibition method performed on the serum pool of four patients with positive RAST results. Significant inhibition of more than 50% by LCL washing fluid at a dilution extract was found at a dilution of 1:10 and by homogenized LCL extract at a dilution of 1:100. No significant inhibition of LCL-IgE binding by dermatophagoides, parietaria and milk antigens was found. This study demonstrated that LCL emanations are potent sensitizers and elicit IgE-mediated asthma.

  1. The effect of sleep deprivation on leadership behaviour in military officers: an experimental study.

    PubMed

    Olsen, Olav Kjellevold; Pallesen, Ståle; Torsheim, Torbjørn; Espevik, Roar

    2016-12-01

    While several studies show that leaders frequently lack sleep, little is known about how this influences leadership behaviour. The present study encompasses an experiment that investigated how three main types of leadership behaviour: transformational (four sub-facets); transactional (two sub-facets); and passive-avoidant (two sub-facets) leadership differed across a rested and a long-term, partially sleep-deprived condition. A total of 16 military naval officers participated. In both conditions, the leaders managed a team of three subordinates in a navy navigation simulator, instructed to complete a specific mission (A or B). Both sleep state (rested or sleep deprived) and mission were counterbalanced. Leadership behaviour was video recorded and subsequently rated on the three leadership behaviours. Overall, the scores on transformational leadership (and on two of four sub-facets) and transactional leadership (on both sub-facets) decreased from the rested to sleep-deprived condition, whereas scores on passive-avoidant leadership overall (and on both sub-facets) increased from the rested to sleep-deprived condition. This study underscores the importance of including sleep as a potentially important determinant when assessing leadership effectiveness. © 2016 European Sleep Research Society.

  2. The Clusters AgeS Experiment (CASE). Variable Stars in the Field of the Globular Cluster M12

    NASA Astrophysics Data System (ADS)

    Kaluzny, J.; Thompson, I. B.; Narloch, W.; Pych, W.; Rozyczka, M.

    2015-09-01

    The field of the globular cluster M12 (NGC 6218) was monitored between 1995 and 2009 in a search for variable stars. BV light curves were obtained for thirty-six periodic or likely periodic variable stars. Thirty-four of these are new detections. Among the latter we identified twenty proper-motion members of the cluster: six detached or semi-detached eclipsing binaries, five contact binaries, five SX Phe pulsators, and three yellow stragglers. Two of the eclipsing binaries are located in the turnoff region, one on the lower main sequence and the remaining three among the blue stragglers. Two contact systems are blue stragglers, and the remaining three reside in the turnoff region. In the blue straggler region a total of 103 objects were found, of which 42 are proper motion members of M12, and another four are field stars. 55 of the remaining objects are located within two core radii from the center of the cluster, and as such they are likely genuine blue stragglers. We also report the discoveries of a radial color gradient of M12, and the shortest period among contact systems in globular clusters in general.

  3. Evaluation of four designs of short implants placed in atrophic areas with reduced bone height: a three-year, retrospective, clinical and radiographic study.

    PubMed

    Lopez Torres, J A; Gehrke, S A; Calvo Guirado, J L; Aristazábal, L F R

    2017-09-01

    The aim of the present study was to evaluate retrospectively the clinical and radiographic behaviour of four commercially-available short implants with different macrodesigns and microdesigns in areas in which the height of the bone was reduced. We took into account the success and survival, peri-implant crestal bone loss, and the level of probing at which the gum bled. Patients were included if they had been given one or more short implants (≤8.5mm long) in the posterior jaws at least three years earlier. Three hundred and ninety-one short implants were placed in 170 subjects, and were divided in four groups based on the brand of implant. The implants were evaluated one, two, and three years after they had been inserted. Short implants had a three-year survival and success rate of 90% in all groups, and bone loss was acceptable after three years with no significant differences between them. These results support the use of short implants as an effective and safe treatment. However, within the limitations of this study, the design of the implant does seem to influence the behaviour of peri-implant bone at the crestal level. Copyright © 2017. Published by Elsevier Ltd.

  4. Rapid development of microsatellite markers with 454 pyrosequencing in a vulnerable fish, the mottled skate, Raja pulchra.

    PubMed

    Kang, Jung-Ha; Park, Jung-Youn; Jo, Hyun-Su

    2012-01-01

    The mottled skate, Raja pulchra, is an economically valuable fish. However, due to a severe population decline, it is listed as a vulnerable species by the International Union for Conservation of Nature. To analyze its genetic structure and diversity, microsatellite markers were developed using 454 pyrosequencing. A total of 17,033 reads containing dinucleotide microsatellite repeat units (mean, 487 base pairs) were identified from 453,549 reads. Among 32 loci containing more than nine repeat units, 20 primer sets (62%) produced strong PCR products, of which 14 were polymorphic. In an analysis of 60 individuals from two R. pulchra populations, the number of alleles per locus ranged from 1-10, and the mean allelic richness was 4.7. No linkage disequilibrium was found between any pair of loci, indicating that the markers were independent. The Hardy-Weinberg equilibrium test showed significant deviation in two of the 28 single-loci after sequential Bonferroni's correction. Using 11 primer sets, cross-species amplification was demonstrated in nine related species from four families within two classes. Among the 11 loci amplified from three other Rajidae family species; three loci were polymorphic. A monomorphic locus was amplified in all three Rajidae family species and the Dasyatidae family. Two Rajidae polymorphic loci amplified monomorphic target DNAs in four species belonging to the Carcharhiniformes class, and another was polymorphic in two Carcharhiniformes species.

  5. Energy spectra of small bosonic clusters having a large two-body scattering length

    NASA Astrophysics Data System (ADS)

    Gattobigio, M.; Kievsky, A.; Viviani, M.

    2012-10-01

    In this work we investigate small clusters of bosons using the hyperspherical harmonic basis. We consider systems with A=2,3,4,5,6 particles interacting through a soft interparticle potential. In order to make contact with a real system, we use an attractive Gaussian potential that reproduces the values of the dimer binding energy and the atom-atom scattering length obtained with one of the most widely used 4He-4He interactions, the LM2M2 potential of Aziz and Slaman. The intensity of the potential is varied in order to explore the clusters’ spectra in different regions with large positive and large negative values of the two-body scattering length. In addition, we include a repulsive three-body force to reproduce the trimer binding energy. With this model, consisting in the sum of a two- and three-body potential, we have calculated the spectrum of the four-, five-, and six-particle systems. In all the regions explored, we have found that these systems present two states, one deep and one shallow close to the A-1 threshold. Some universal relations between the energy levels are extracted; in particular, we have estimated the universal ratios between thresholds of the three-, four-, and five-particle continua using the two-body Gaussian potential. They agree with recent measurements and theoretical predictions.

  6. Rapid Development of Microsatellite Markers with 454 Pyrosequencing in a Vulnerable Fish, the Mottled Skate, Raja pulchra

    PubMed Central

    Kang, Jung-Ha; Park, Jung-Youn; Jo, Hyun-Su

    2012-01-01

    The mottled skate, Raja pulchra, is an economically valuable fish. However, due to a severe population decline, it is listed as a vulnerable species by the International Union for Conservation of Nature. To analyze its genetic structure and diversity, microsatellite markers were developed using 454 pyrosequencing. A total of 17,033 reads containing dinucleotide microsatellite repeat units (mean, 487 base pairs) were identified from 453,549 reads. Among 32 loci containing more than nine repeat units, 20 primer sets (62%) produced strong PCR products, of which 14 were polymorphic. In an analysis of 60 individuals from two R. pulchra populations, the number of alleles per locus ranged from 1–10, and the mean allelic richness was 4.7. No linkage disequilibrium was found between any pair of loci, indicating that the markers were independent. The Hardy–Weinberg equilibrium test showed significant deviation in two of the 28 single-loci after sequential Bonferroni’s correction. Using 11 primer sets, cross-species amplification was demonstrated in nine related species from four families within two classes. Among the 11 loci amplified from three other Rajidae family species; three loci were polymorphic. A monomorphic locus was amplified in all three Rajidae family species and the Dasyatidae family. Two Rajidae polymorphic loci amplified monomorphic target DNAs in four species belonging to the Carcharhiniformes class, and another was polymorphic in two Carcharhiniformes species. PMID:22837688

  7. Seven novel mutations of the SMPD1 gene in four Chinese patients with Niemann-Pick disease type A and prenatal diagnosis for four fetuses.

    PubMed

    Ding, Yuan; Li, Xiyuan; Liu, Yupeng; Hua, Ying; Song, Jinqing; Wang, Liwen; Li, Mengqiu; Qin, Yaping; Yang, Yanling

    2016-04-01

    Niemann-Pick disease type A (NPD-A) is a rare autosomal recessive lysosomal storage disorder caused by acid sphingomyelinase deficiency. Only a few cases have been documented in mainland China, and prenatal diagnosis has not been performed to date. In this study, the clinical and laboratory features of four Chinese patients with early-onset NPD-A were summarized. Four patients with NPD-A were the firstborns of non-consanguineous parents from four unrelated Chinese families. Bone marrow analysis, acid sphingomyelinase assay and genetic studies were performed. SMPD1 gene studies on amniocytes were performed for the prenatal diagnosis of four fetuses from three families. Four patients were admitted at the age of 1-10 months due to jaundice, hepatosplenomegaly and psychomotor retardation. Liver histopathological analysis revealed glucolipid accumulation. Massive foamy histiocytes were found in the bone marrow. Acid sphingomyelinase activities of peripheral blood leukocytes were significantly decreased (4.05-21.9 nmol/h/mg protein, normal range 216.1-950.9 nmol/h/mg protein). Seven novel mutations (c.518-519insT, c.562_563insC, c.792Gdel, c.949G>A, c.1487_1499delACCGTGTGTACCA, c.1495T>C and c.1670T>C) of the SMPD1 gene were identified in four patients. Only one fetus had two mutations of the SMPD1 gene of amniocytes. The results suggested that the fetus was affected by NPD-A. The mother chose artificial abortion. The other three fetuses were not affected by NPD-A. No mutation of the SMPD1 gene was detected in the cultured amniocytes from the mothers. Postnatal genetic analysis and normal development of the three infants confirmed the prenatal diagnosis. Seven novel mutations associated with NPD-A were identified in the Chinese population. Prenatal diagnosis for four fetuses of three families was successfully performed by amniocyte gene analysis. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  8. Comparison of Three Reconstructive Techniques in the Surgical Management of Patients With Four-Level Cervical Spondylotic Myelopathy.

    PubMed

    Li, Zhonghai; Wang, Huadong; Tang, Jiaguang; Ren, Dongfeng; Li, Li; Hou, Shuxun; Zhang, Hailong; Hou, Tiesheng

    2017-05-15

    Retrospective clinical series. To compare perioperative parameters, clinical outcomes, radiographic parameters, and complication rates of three reconstructive techniques after the anterior decompression of four-level cervical spondylotic myelopathy (CSM). At present, the decision to treat multilevel CSM, especially four-level CSM, remains controversial. No one compares multilevel anterior cervical discectomy and fusion (mACDF), segmental anterior cervical corpectomy and fusion (sACCF) to multilevel anterior cervical discectomy and fusion with cage alone (mACDF-CA) in four-level constructs. Between July 2006 and February 2014, 97 consecutive patients with four-level CSM were enrolled in this study and divided into sACCF (n = 39) group, mACDF (n = 31) group, and mACDF-CA (n = 27) group. The study compared perioperative parameters, complication rates, clinical and radiologic parameters of three reconstructive techniques after the anterior decompression of four-level CSM. The mACDF-CA group had the least bleeding and cost of index surgery compared with the sACCF group having the most bleeding and cost. Although significant pain relief and functional activity improvement have been achieved in the three groups at the final follow-up, there was no significant difference in the Japanese Orthopedic Association, SF-36 and NDI scores among the three groups (P >0.05). The mACDF group maintained the best cervical lordosis at the final follow-up, compared with the sACCF group maintained the worst cervical lordosis. Solid fusion was achieved in 87.1% of subjects in sACCF group, 90.3% in mACDF, and in 88.9% in mACDF-CA. The mACDF-CA group had a higher rate of subsidence and lower rate of dysphagia than other two groups. mACDF-CA can be considered an effective and safe alternative procedure in the treatment of the four-level CSM. 4.

  9. 33 CFR 83.35 - Sound signals in restricted visibility (Rule 35).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... more than 2 minutes two prolonged blasts in succession with an interval of about 2 seconds between them... than 2 minutes, three blasts in succession; namely, one prolonged followed by two short blasts. (d..., shall at intervals of not more than 2 minutes sound four blasts in succession; namely, one prolonged...

  10. 33 CFR 83.35 - Sound signals in restricted visibility (Rule 35).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... more than 2 minutes two prolonged blasts in succession with an interval of about 2 seconds between them... than 2 minutes, three blasts in succession; namely, one prolonged followed by two short blasts. (d..., shall at intervals of not more than 2 minutes sound four blasts in succession; namely, one prolonged...

  11. 33 CFR 83.35 - Sound signals in restricted visibility (Rule 35).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... more than 2 minutes two prolonged blasts in succession with an interval of about 2 seconds between them... than 2 minutes, three blasts in succession; namely, one prolonged followed by two short blasts. (d..., shall at intervals of not more than 2 minutes sound four blasts in succession; namely, one prolonged...

  12. 33 CFR 83.35 - Sound signals in restricted visibility (Rule 35).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... more than 2 minutes two prolonged blasts in succession with an interval of about 2 seconds between them... than 2 minutes, three blasts in succession; namely, one prolonged followed by two short blasts. (d..., shall at intervals of not more than 2 minutes sound four blasts in succession; namely, one prolonged...

  13. Construction of a wireless communication contact closure system for liquid chromatography with multiple parallel mass spectrometers and other detectors

    USDA-ARS?s Scientific Manuscript database

    A contact closure system has been constructed and implemented that utilizes two contact closure sender boards that communicate wirelessly to four contact closure receiver boards to distribute start signals from two or three liquid chromatographs to fourteen instruments, pumps, detectors, or other co...

  14. Two-Way and Monolingual English Immersion in Preschool Education: An Experimental Comparison

    ERIC Educational Resources Information Center

    Barnett, W. Steven; Yarosz, Donald J.; Thomas, Jessica; Jung, Kwanghee; Blanco, Dulce

    2007-01-01

    An experimental study was conducted comparing the effects of dual language, or two-way immersion (TWI) and monolingual English immersion (EI) preschool education programs on children's learning. Three-and four-year old children were randomly assigned by lottery to either a newly established TWI Spanish/English program or a monolingual English…

  15. Diprosopia/dicephalia in calves in northern Italy: clinical and aetio-pathological features.

    PubMed

    Biasibetti, E; D'Angelo, A; Bellino, C; Gay, L; Gianella, P; Capucchio, M T

    2011-12-01

    Cephalic parapagia, a rare congenital anomaly caused by the fusion of two monozygotic embryos, is characterized by a single body and a spectrum of duplication of craniofacial structures. The authors describe the clinical and pathological aspects of the parapagus conjoined twin defect in nine calves referred to the Department of Animal Pathology, Turin, between 1999 and 2009. The majority of the calves (eight cases) presented two snouts that shared three or four eyes (diprosopia); one calf presented two separate skulls fused at the foramen magnum (dicephalia). Bilateral inferior brachygnathia was observed in four calves. Post-mortem examination of the skull revealed complete brain duplication with fusion at the caudal portion of the brainstem in all calves. Histological features of the cerebral hemispheres and brainstem were normal; moderate disorganization of the cerebellar cortex was noted in two cases. Cardiac malformations were observed in three calves. No aetiologic cause was determined. This article underscores the importance of diprosopia in cattle species and suggests the need for more detailed investigations to better understand its pathogenesis. © 2011 Blackwell Verlag GmbH.

  16. Sarcocystis sp. in mountain goats (Oreamnos americanus) in Washington: prevalence and search for the definitive host.

    PubMed

    Foreyt, W J

    1989-10-01

    During October and November 1986, Sarcocystis sp. was detected in 24 of 56 (43%) tongues from hunter-killed mountain goats (Oreamnos americanus) in Washington (USA). Sarcocysts had an unusual sessile polyp-shaped branched wall. Mean size of 154 sarcocysts was 71.3 x 37.8 microns (range, 20 to 248 x 10 to 120 microns), and the mean intensity was 2.3 (range, 1 to 28). In an attempt to identify the definitive host, infected tongues were fed to four coyotes (Canis latrans), eight domestic dogs, four domestic cats, three bears (Ursus americanus), two raccoons (Procyon lotor), two martens (Martes americana), two fishers (Martes pennanti), three skunks (Mephitis mephitis), five mink (Mustela vison), five ferrets (Mustela putorius), one pigtail macaque (Macaca nemestrina), two red-tailed hawks (Buteo jamaicensis) and one great horned owl (Bubo virginianus). Oocysts or sporocysts were not detected in the feces of any host for less than or equal to 20 days after ingestion of the infected meat. The definitive host for Sarcocystis sp. in mountain goats was not identified.

  17. Determination of Residual Stresses in Rails

    DOT National Transportation Integrated Search

    1983-05-01

    A destructive sectioning technique for measuring the complete three-dimensional residual stresses in a rail cross section was developed. The technique was applied to four tangent rail specimens: two 136-pound specimens were taken from FAST (Facility ...

  18. Novel 3D Tissue Engineered Bone Model, Biomimetic Nanomaterials, and Cold Atmospheric Plasma Technique for Biomedical Applications

    NASA Astrophysics Data System (ADS)

    Wang, Mian

    This thesis research is consist of four chapters, including biomimetic three-dimensional tissue engineered nanostructured bone model for breast cancer bone metastasis study (Chapter one), cold atmospheric plasma for selectively ablating metastatic breast cancer (Chapter two), design of biomimetic and bioactive cold plasma modified nanostructured scaffolds for enhanced osteogenic differentiation of bone marrow derived mesenchymal stem cells (Chapter three), and enhanced osteoblast and mesenchymal stem cell functions on titanium with hydrothermally treated nanocrystalline hydroxyapatite/magnetically treated carbon nanotubes for orthopedic applications (Chapter four). All the thesis research is focused on nanomaterials and the use of cold plasma technique for various biomedical applications.

  19. Multiple lentigines, myxoid tumours and endocrine overactivity; four cases of Carney's complex.

    PubMed

    Handley, J; Carson, D; Sloan, J; Walsh, M; Thornton, C; Hadden, D; Bingham, E A

    1992-04-01

    Four patients with Carney's complex, one sporadic and three familial, are described. The sporadic case was a young male with centrofacial lentigines, who developed cyclical Cushing's syndrome secondary to bilateral pigmented nodular adrenocortical disease, two separate left atrial myxomas, and buccal mucosal myxomas. The three familial cases, who all had varying degrees of centrofacial/mucosal lentigines and cutaneous myxoid tumours, were a woman with myxoid mammary fibroadenomatosis and a left atrial myxoma, her daughter who developed a prolactin-secreting pituitary adenoma, and her son who had bilateral large-cell calcified Sertoli cell testicular tumours, and an axillary psammomatous melanotic schwannoma.

  20. Infertility among kidney transplant recipients.

    PubMed

    Ghazizadeh, Shirin; Lessan-Pezeshki, Mahboob; Khatami, Mohammd R; Mahdavi-Mazdeh, Mitra; Abbasi, Mohammad R; Azmandian, Jalal; Razeghi, Effat; Seifi, Sepideh; Ahmadi, Farrokh; Maziar, Sima

    2007-03-01

    We studied 122 women with a transplanted kidney to evaluate their reproductive performance. 15 of the patients were either post-menopausal or underwent hysterectomy and 33 were unmarried. Of the 76 married reproductive age women, 10 (13.1%) were infertile. Three had male factor infertility, three had ovulatory problems and in four cases, the cause was uncertain. Six of these patients were actively treated by ovulation induction with or without IUI and two of these patients became pregnant. The remaining four patients refused treatment for infertility. We conclude that the incidence of infertility among kidney transplant recipients is similar to the general population, but they are less motivated to be treated for infertility.

  1. [Catamenial pneumothorax secondary to thoracic endometriosis].

    PubMed

    Mendoza Calderón, Fernando; Valladares, Virgilio; Ballesteros, Alberto; Ayala, María de la Merced

    2007-11-01

    It is a 27 years old patient, childbirths three, menarche 13 years, regular cycles, with dismenorrea incapacitante twice a year, referring light dispareunia, which was refered a our hospital. She had been hospitalized three days ago presenting left neumotorax, it was the third time she have had the same clinical square in the last four months, she had a neumotorax of 40%, Ca 125 de 102 U/ml, the pelvic ultrasound reported like positive anecoica image of five for four centimeters, through a toracoscopy in which reported two focuses endometriosicos of aproximately 0.5 centimeters, from which a biopsy was obtained and reported tissue endometrium in lung parenchyma.

  2. Effects of size on three-cone bit performance in laboratory drilled shale

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Black, A.D.; DiBona, B.G.; Sandstrom, J.L.

    1982-09-01

    The effects of size on the performance of 3-cone bits were measured during laboratory drilling tests in shale at simulated downhole conditions. Four Reed HP-SM 3-cone bits with diameters of 6 1/2, 7 7/8, 9 1/2 and 11 inches were used to drill Mancos shale with water-based mud. The tests were conducted at constant borehole pressure, two conditions of hydraulic horsepower per square inch of bit area, three conditions of rotary speed and four conditions of weight-on-bit per inch of bit diameter. The resulting penetration rates and torques were measured. Statistical techniques were used to analyze the data.

  3. Confirmation of Nosocomial Transmission of Hepatitis C Virus by Phylogenetic Analysis of the NS5-B Region

    PubMed Central

    Norder, Heléne; Bergström, Åsa; Uhnoo, Ingrid; Aldén, Jöran; Weiss, Lars; Czajkowski, Jan; Magnius, Lars

    1998-01-01

    Four hepatitis C virus transmission chains at three dialysis units were disclosed by limited sequencing; three of these were disclosed by analysis of the NS5-B region of the genome. Dialysis on the same shift as that during which infected patients were dialyzed was the common factor for seven patients in two chains. Two nurses exposed to needle sticks and their sources of infection constituted two other chains. The strains of three chains belonged to subtype 1a and formed clusters with an intrachain variability of 0 to 6 nucleotides compared to 8 to 37 nucleotides for unrelated strains within this subtype. The clusters were supported by bootstrap values ranging from 89 to 100%. PMID:9738071

  4. An Empirical Study on Teaching Urban Young Children Music and English by Contrastive Elements of Music and Songs

    ERIC Educational Resources Information Center

    Lee, Ling-Yu Liza

    2009-01-01

    The purpose of the study is to teach urban young children music concepts and English by composing creative music and songs with contrast elements. The subjects were seven urban young children aged from three to four in a Taiwan kindergarten. The duration was twenty-four weeks, with two sessions per week. The teaching contents included Hello Song,…

  5. Validation of a poison prevention program.

    PubMed Central

    Braden, B T

    1979-01-01

    The effectiveness of an empirically designed poison warning label and an educational program for three and four year old children was assessed in four groups of 39 such children, with one group serving as a control. The educational program appeared to improve intellectual (verbal) awareness of poisons, the label to improve visual discrimination, and the combination of the two to have the greatest overall impact. Images p943-a PMID:474851

  6. A Canopy Density Model for Planar Orchard Target Detection Based on Ultrasonic Sensors

    PubMed Central

    Li, Hanzhe; Zhai, Changyuan; Weckler, Paul; Wang, Ning; Yang, Shuo; Zhang, Bo

    2016-01-01

    Orchard target-oriented variable rate spraying is an effective method to reduce pesticide drift and excessive residues. To accomplish this task, the orchard targets’ characteristic information is needed to control liquid flow rate and airflow rate. One of the most important characteristics is the canopy density. In order to establish the canopy density model for a planar orchard target which is indispensable for canopy density calculation, a target density detection testing system was developed based on an ultrasonic sensor. A time-domain energy analysis method was employed to analyze the ultrasonic signal. Orthogonal regression central composite experiments were designed and conducted using man-made canopies of known density with three or four layers of leaves. Two model equations were obtained, of which the model for the canopies with four layers was found to be the most reliable. A verification test was conducted with different layers at the same density values and detecting distances. The test results showed that the relative errors of model density values and actual values of five, four, three and two layers of leaves were acceptable, while the maximum relative errors were 17.68%, 25.64%, 21.33% and 29.92%, respectively. It also suggested the model equation with four layers had a good applicability with different layers which increased with adjacent layers. PMID:28029132

  7. Noninvasive pulsed radio frequency energy in the treatment of occipital neuralgia with chronic, debilitating headache: a report of four cases.

    PubMed

    Stall, Robert S

    2013-05-01

    To examine the effects of noninvasive pulsed radio frequency energy (PRFE) on recurrent migraine headache associated with occipital neuralgia. Four patients who were receiving long-term treatment with repeated greater and lesser occipital nerve blocks (GLONBs) to control recurrent migraine resistant to other treatment underwent treatment with noninvasive PRFE at home as a substitute for GLONB treatment. PRFE was administered by the patient at home for 30 minutes twice daily through an applicator pad placed directly over the occiput and upper cervical spine. Three of four patients reported a decrease in frequency, severity, or both of nonprostrating and prostrating migraines compared with their baseline symptoms; one reported no change from baseline. Comparing PRFE results with those obtained after nerve blocks, three of four patients reported decreases in nonprostrating migraines, while two reported a decrease in prostrating migraines. One patient reported an increase in prostrating migraine frequency. Variable degrees of increased productivity, decreased opioid and nonopioid analgesic use, and decreased visits to urgent care clinics were noted. In two patients who had combined PRFE and GLONB, marked improvement was noted in all symptoms. Improvement in frequency of headaches was noted, especially when PRFE was combined with GLONB. Further study is warranted. Wiley Periodicals, Inc.

  8. Performance of four different rat strains in the autoshaping, two-object discrimination, and swim maze tests of learning and memory.

    PubMed

    Andrews, J S; Jansen, J H; Linders, S; Princen, A; Broekkamp, C L

    1995-04-01

    The performance of four strains of rats commonly used in behavioural research was assessed in three different tests of learning and memory. The four strains included three outbred lines (Long-Evans, Sprague-Dawley, Wistar) and one inbred strain (S3). Learning and memory were tested using three different paradigms: autoshaping of a lever press, a two-object discrimination test, and performance in a two-island swim maze task. The pigmented strains showed better performance in the autoshaping procedure: the majority of the Long-Evans and the S3 rats acquired the response, and the majority of the Wistar and Sprague-Dawley failed to acquire the response in the set time. The albino strains were slightly better in the swim maze than the pigmented strains. There appeared to be a speed/accuracy trade-off in the strategy used to solve the task. This was also evident following treatment with the cholinergic-depleting agent hemicholinium-3. The performance of the Long-Evans rats was most affected by the treatment in terms of accuracy and the Wistar and Sprague-Dawleys in terms of speed. In the two-object discrimination test only the Long-Evans showed satisfactory performance and were able to discriminate a novel from a known object a short interval after initial exposure. These results show large task- and strain-dependent differences in performance in tests of learning and memory. Some of the performance variation may be due to emotional differences between the strains and may be alleviated by extra training. However, the response to pharmacological manipulation may require more careful evaluation.(ABSTRACT TRUNCATED AT 250 WORDS)

  9. Few-body resonances of unequal-mass systems with infinite interspecies two-body s-wave scattering length

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blume, D.; Daily, K. M.

    Two-component Fermi and Bose gases with infinitely large interspecies s-wave scattering length a{sub s} exhibit a variety of intriguing properties. Among these are the scale invariance of two-component Fermi gases with equal masses, and the favorable scaling of Efimov features for two-component Bose gases and Bose-Fermi mixtures with unequal masses. This paper builds on our earlier work [Phys. Rev. Lett. 105, 170403 (2010)] and presents a detailed discussion of our studies of small unequal-mass two-component systems with infinite a{sub s} in the regime where three-body Efimov physics is absent. We report on nonuniversal few-body resonances. Just like with two-body systemsmore » on resonance, few-body systems have a zero-energy bound state in free space and a diverging generalized scattering length. Our calculations are performed within a nonperturbative microscopic framework and investigate the energetics and structural properties of small unequal-mass two-component systems as functions of the mass ratio {kappa}, and the numbers N{sub 1} and N{sub 2} of heavy and light atoms. For purely attractive Gaussian two-body interactions, we find that the (N{sub 1},N{sub 2})=(2,1) and (3,1) systems exhibit three-body and four-body resonances at mass ratios {kappa}=12.314(2) and 10.4(2), respectively. The three- and four-particle systems on resonance are found to be large. It seems feasible that the features discussed in this paper can be probed experimentally with present-day technology.« less

  10. Toxoplasmosis in golden-headed lion tamarins (Leontopithecus chrysomelas) and emperor marmosets (Saguinus imperator) in captivity.

    PubMed

    Epiphanio, S; Guimarães, M A; Fedullo, D L; Correa, S H; Catão-Dias, J L

    2000-06-01

    From 1991 to 1995, eight New World nonhuman primates of the family Callitrichidae belonging to the collection of Fundacão Parque Zoologico de São Paulo died of toxoplasmosis. Of the eight affected nonhuman primates, four were Leontopithecus chrysomelas (one male, three females) and four were Saguinus imperator (two males, two females). The most commonly affected organs were the lungs, liver, and lymph nodes, with hemorrhagic and necrotic lesions. Histopathologic examination revealed protozoa that were morphologically consistent with Toxoplasma gondii. Immunohistochemical assays were strongly positive for T. gondii.

  11. Review of nutrition labeling formats.

    PubMed

    Geiger, C J; Wyse, B W; Parent, C R; Hansen, R G

    1991-07-01

    This article examines nutrition labeling history as well as the findings of nine research studies of nutrition labeling formats. Nutrition labeling regulations were announced in 1973 and have been periodically amended since then. In response to requests from consumers and health care professionals for revision of the labeling system, the Food and Drug Administration initiated a three-phase plan for reform of nutrition labeling in 1990. President Bush signed the Nutrition Labeling and Education Act in November 1990. Literature analysis revealed that only nine studies with an experimental design have focused on nutrition labeling since 1971. Four were conducted before 1975, which was the year that nutrition labeling was officially implemented, two were conducted in 1980, and three were conducted after 1986. Only two of the nine studies supported the traditional label format mandated by the Code of Federal Regulations, and one study partially supported it. Four of the nine studies that evaluated graphic presentations of nutrition information found that consumer comprehension of nutrition information was improved with a graphic format for nutrition labeling: three studies supported the use of bar graphs and one study supported the use of a pie chart. Full disclosure (ie, complete nutrient and ingredient labeling) was preferred by consumers in two of the three studies that examined this variable. The third study supported three types of information disclosure dependent upon socioeconomic class. In those studies that tested graphics, a bar graph format was significantly preferred and showed better consumer comprehension than the traditional format.

  12. Solute transport with multiple equilibrium-controlled or kinetically controlled chemical reactions

    USGS Publications Warehouse

    Friedly, John C.; Rubin, Jacob

    1992-01-01

    A new approach is applied to the problem of modeling solute transport accompanied by many chemical reactions. The approach, based on concepts of the concentration space and its stoichiometric subspaces, uses elements of the subspaces as primary dependent variables. It is shown that the resulting model equations are compact in form, isolate the chemical reaction expressions from flow expressions, and can be used for either equilibrium or kinetically controlled reactions. The implications of the results on numerical algorithms for solving the equations are discussed. The application of the theory is illustrated throughout with examples involving a simple but broadly representative set of reactions previously considered in the literature. Numerical results are presented for four interconnected reactions: a homogeneous complexation reaction, two sorption reactions, and a dissolution/precipitation reaction. Three cases are considered: (1) four kinetically controlled reactions, (2) four equilibrium-controlled reactions, and (3) a system with two kinetically controlled reactions and two equilibrium-controlled reactions.

  13. Hamiltonian dynamics of thermostated systems: two-temperature heat-conducting phi4 chains.

    PubMed

    Hoover, Wm G; Hoover, Carol G

    2007-04-28

    We consider and compare four Hamiltonian formulations of thermostated mechanics, three of them kinetic, and the other one configurational. Though all four approaches "work" at equilibrium, their application to many-body nonequilibrium simulations can fail to provide a proper flow of heat. All the Hamiltonian formulations considered here are applied to the same prototypical two-temperature "phi4" model of a heat-conducting chain. This model incorporates nearest-neighbor Hooke's-Law interactions plus a quartic tethering potential. Physically correct results, obtained with the isokinetic Gaussian and Nose-Hoover thermostats, are compared with two other Hamiltonian results. The latter results, based on constrained Hamiltonian thermostats, fail to model correctly the flow of heat.

  14. Three Dimensions and Four Levels: Towards a Methodology for Comparative Religious Education

    ERIC Educational Resources Information Center

    Bråten, Oddrun Marie Hovde

    2015-01-01

    This article is an abstract of a suggested methodology for comparative studies in religious education. It is based on a study where religious education in state schools in England and Norway were compared. The methodology is a synthesis of two sets of ideas. The first is an idea of three dimensions in comparative education: supranational, national…

  15. Intra-Family Diffusion of Selected Cognitive Skills as a Function of Educational Stimulation.

    ERIC Educational Resources Information Center

    Gilmer, Barbara R.

    1969-01-01

    In order to investigate diffusion effects within families involved in an intervention program, 80 disadvantaged children were divided into four groups, three of which were made up of younger siblings of preschool children in the intervention program. In two of these three groups, the mother was also involved in the program. The fourth group was…

  16. Is Three a Crowd? Exploring the Development and Satisfaction of Students in Triples

    ERIC Educational Resources Information Center

    Long, Larry D.; Kujawa, Kyle

    2015-01-01

    Tripling, the assignment of a third resident to a room designed for two, is a common practice at many colleges and universities across the United States. Most of the research on tripling was conducted three or four decades ago, and research exploring how living in a triple affects the educational gains and satisfaction of college students is…

  17. Enhancing the English-Language Oral Skills of International Students through Drama

    ERIC Educational Resources Information Center

    Gill, Chamkaur

    2013-01-01

    Ten non-English-speaking-background students of Bond University were observed to identify the effects of drama on oral English. Over a period of twelve weeks (two hours per week), elements of their oral English communication were measured. The weeks were divided into four lots of three weeks each, with the first three weeks made up entirely of…

  18. Songbird nest survival is invariant to early-successional restoration treatments in a large river floodplain

    Treesearch

    Dirk E. Burhans; Brian G. Root; Terry L. Shaffer; Daniel C. Dey

    2010-01-01

    We monitored songbird nest survival in two reforesting, ∼50-ha former cropland sites along the Missouri River in central Missouri from 2001 to 2003. Sites were partitioned into three experimental units, each receiving one of three tree planting treatments. Nest densities varied among restoration treatments for four of five species, but overall nest survival...

  19. Lack of mutagens in deep-fat-fried foods obtained at the retail level.

    PubMed

    Taylor, S L; Berg, C M; Shoptaugh, N H; Scott, V N

    1982-04-01

    The basic methylene chloride extract from 20 of 30 samples of foods fried in deep fat failed to elicit any mutagenic response that could be detected in the Salmonella typhimurium/mammalian microsome assay. The basic extracts of the remaining ten samples (all three chicken samples studied, two of the four potato-chip samples, one of four corn-chip samples, the sample of onion rings, two of six doughnuts, and one of three samples of french-fried potato) showed evidence of weak mutagenic activity. In these samples, amounts of the basic extract equivalent to 28.5-57 g of the original food sample were required to produce revertants at levels of 2.6-4.8 times the background level. Only two of the acidic methylene chloride extracts from the 30 samples exhibited mutagenic activity greater than 2.5 times the background reversion level, and in both cases (one corn-chip and one shrimp sample) the mutagenic response was quite weak. The basic extract of hamburgers fried in deep fat in a home-style fryer possessed higher levels of mutagenic activity (13 times the background reversion level). However, the mutagenic activity of deep-fried hamburgers is some four times lower than that of pan-fried hamburgers.

  20. Direct observation of interlocked domain walls and topological four-state vortex-like domain patterns in multiferroic YMnO{sub 3} single crystal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tian, Lei; School of Materials Science and Engineering, Dalian Jiaotong University, Dalian, Liaoning 116028; Wang, Yumei, E-mail: wangym@iphy.ac.cn

    2015-03-16

    Using the advanced spherical aberration-corrected high angle annular dark field scanning transmission electron microscope imaging techniques, we investigated atomic-scale structural features of domain walls and domain patterns in YMnO{sub 3} single crystal. Three different types of interlocked ferroelectric-antiphase domain walls and two abnormal topological four-state vortex-like domain patterns are identified. Each ferroelectric domain wall is accompanied by a translation vector, i.e., 1/6[210] or −1/6[210], demonstrating its interlocked nature. Different from the four-state vortex domain patterns caused by a partial edge dislocation, two four-state vortex-like domain configurations have been obtained at atomic level. These observed phenomena can further extend our understandingmore » of the fascinating vortex domain patterns in multiferroic hexagonal rare-earth manganites.« less

  1. Recent change in congenital syphilis in Korea: Retrospective 10 year study.

    PubMed

    Kang, Sung-Han; Lee, Ji-Hyun; Choi, Sun-Hee; Lee, Jin; Yoon, Hoi Soo; Cha, Sung-Ho; Choi, Yong-Sung

    2015-12-01

    This study was conducted to evaluate recent clinical and anthropologic features of neonates with reactive serology for syphilis and their mothers from three institutions in Korea over an 11-year-period. The medical records of 20 neonates with reactive serology for syphilis and their mothers at three centers (Kyung Hee University Hospital, Kyung Hee University Hospital at Gangdong, and Korea Electric Power Corporation Hospital) seen between January 2000 and December 2010 were reviewed retrospectively. Among 20 mothers, 16 (80%) were native Korean and four (20%) were foreign-born immigrants. Two mothers (10%) were unmarried. The annual distribution of cases was three (15%) in 2000, one each (5%) in 2005 and 2006, respectively, two each (10%) in 2007 and 2008, respectively, six (30%) in 2009, and five (25%) in 2010. Just over half (55%) occurred across 2009 and 2010. All neonates, by definition, were diagnosed with presumptive congenital syphilis (CS). Among the neonates, four had positive cerebrospinal fluid venereal disease research laboratory test, and three exhibited symptoms and signs. In three centers in Seoul, Korea, the observed number of CS cases was higher in 2009 and 2010 than in previous years. This finding is consistent with a trend toward increasing prevalence of international marriage and suggests that more meticulous screening of CS is needed. © 2015 Japan Pediatric Society.

  2. Validity of four approaches of using repeaters' MCAT scores in medical school admissions to predict USMLE Step 1 total scores.

    PubMed

    Zhao, Xiaohui; Oppler, Scott; Dunleavy, Dana; Kroopnick, Marc

    2010-10-01

    This study investigated the validity of four approaches (the average, most recent, highest-within-administration, and highest-across-administration approaches) of using repeaters' Medical College Admission Test (MCAT) scores to predict Step 1 scores. Using the differential predication method, this study investigated the magnitude of differences in the expected Step 1 total scores between MCAT nonrepeaters and three repeater groups (two-time, three-time, and four-time test takers) for the four scoring approaches. For the average score approach, matriculants with the same MCAT average are expected to achieve similar Step 1 total scores regardless of whether the individual attempted the MCAT exam one or multiple times. For the other three approaches, repeaters are expected to achieve lower Step 1 scores than nonrepeaters; for a given MCAT score, as the number of attempts increases, the expected Step 1 decreases. The effect was strongest for the highest-across-administration approach, followed by the highest-within-administration approach, and then the most recent approach. Using the average score is the best approach for considering repeaters' MCAT scores in medical school admission decisions.

  3. Random-effects linear modeling and sample size tables for two special crossover designs of average bioequivalence studies: the four-period, two-sequence, two-formulation and six-period, three-sequence, three-formulation designs.

    PubMed

    Diaz, Francisco J; Berg, Michel J; Krebill, Ron; Welty, Timothy; Gidal, Barry E; Alloway, Rita; Privitera, Michael

    2013-12-01

    Due to concern and debate in the epilepsy medical community and to the current interest of the US Food and Drug Administration (FDA) in revising approaches to the approval of generic drugs, the FDA is currently supporting ongoing bioequivalence studies of antiepileptic drugs, the EQUIGEN studies. During the design of these crossover studies, the researchers could not find commercial or non-commercial statistical software that quickly allowed computation of sample sizes for their designs, particularly software implementing the FDA requirement of using random-effects linear models for the analyses of bioequivalence studies. This article presents tables for sample-size evaluations of average bioequivalence studies based on the two crossover designs used in the EQUIGEN studies: the four-period, two-sequence, two-formulation design, and the six-period, three-sequence, three-formulation design. Sample-size computations assume that random-effects linear models are used in bioequivalence analyses with crossover designs. Random-effects linear models have been traditionally viewed by many pharmacologists and clinical researchers as just mathematical devices to analyze repeated-measures data. In contrast, a modern view of these models attributes an important mathematical role in theoretical formulations in personalized medicine to them, because these models not only have parameters that represent average patients, but also have parameters that represent individual patients. Moreover, the notation and language of random-effects linear models have evolved over the years. Thus, another goal of this article is to provide a presentation of the statistical modeling of data from bioequivalence studies that highlights the modern view of these models, with special emphasis on power analyses and sample-size computations.

  4. A Stratified Study of Students' Understanding of Basic Optics Concepts in Different Contexts Using Two-Tier Multiple-Choice Items

    ERIC Educational Resources Information Center

    Chu, Hye-Eun; Treagust, David F.; Chandrasegaran, A. L.

    2009-01-01

    A large scale study involving 1786 year 7-10 Korean students from three school districts in Seoul was undertaken to evaluate their understanding of basic optics concepts using a two-tier multiple-choice diagnostic instrument consisting of four pairs of items, each of which evaluated the same concept in two different contexts. The instrument, which…

  5. At the foot of the smoking mountains: The 2014 scientific investigations in the Islands of the Four Mountains

    USGS Publications Warehouse

    Hatfield, Virginia; Bruner, Kale; West, Dixie; Savinetsky, Arkady; Krylovich, Olga; Khasanov, Bulat; Vasyukov, Dmitry; Antipushina, Zhanna; Okuno, Mitsuru; Crockford, Susan; Nicolaysen, Kirsten; MacInnes, Breanyn; Persico, Lyman; Izbekov, Pavel; Neal, Christina; Bartlett, Thomas; Loopesko, Lydia; Fulton, Anne

    2016-01-01

    An interdisciplinary research team conducted archaeological, geological, and biological investigations in the Islands of the Four Mountains, Alaska during the summer of 2014 as part of a three-year project to study long-term geological and ecological patterns and processes with respect to human settlement. Researchers investigated three archaeological sites on Chuginadak Island (SAM-0014, SAM-0016 and SAM-0047) and two archaeological sites on Carlisle Island (AMK-0003 and SAM-0034) as well as peat, tephra, and lava deposition on those islands. These investigations resulted in the delineation of archaeological sites, documentation of geological and cultural stratigraphy, excavation of house-pit features, visual characterization and sampling of potential lithic sources, and documentation of Unangan occupation in the Islands of the Four Mountains from roughly 3,800 years ago to Russian contact.

  6. Sinonasal mucosal melanoma: retrospective survival study of 25 patients.

    PubMed

    Vandenhende, C; Leroy, X; Chevalier, D; Mortuaire, G

    2012-02-01

    To determine potential prognostic factors for survival in patients with mucosal malignant melanoma of the sinonasal tract. Patients managed between 1991 and 2008 were assessed retrospectively. The seventh edition Union for International Cancer Control (7th UICC) tumour-node-metastasis classification was used for tumour staging. Kaplan-Meier and log rank tests were used for survival analysis. Twenty-five patients were studied (six were tumour stage three, eight tumour stage four(a) and 11 tumour stage four(b)). Surgery was performed on 23 patients (92 per cent). Fifteen received post-operative radiotherapy. Mean follow up was 31.3 months (range, two to 99 months). Three-year disease-free survival was improved in patients with stage four tumour arising from the nasal fossa, versus other sites, and in those with stage four tumour treated with surgery plus adjuvant radiotherapy, versus other treatments. Patients with melanoma of the nasal cavity have very poor survival rates. Treatment is still based on adequate surgical resection with safe margins. In this study, post-operative radiotherapy improved local control only for stage four tumours.

  7. Leptospira infections in trappers from Ontario

    PubMed Central

    Warshawsky, Bryna; Lindsay, L Robbin; Artsob, Harvey

    2000-01-01

    BACKGROUND: Four trappers presented to the Middlesex-London Health Unit in November, 1997 with similar clinical presentations. All four complained of fever, chills and headache, and three of the four had severe muscle aches. All gave histories of trapping raccoons before the onset of illness. Three of the four men exhibited diagnostic seroconversions to Leptospira grippotyphosa. OBJECTIVE: To describe the four suspected cases of leptospira infections and to determine whether raccoons might serve as a reservoir of infection using field studies. DESIGN: Raccoon serology were undertaken using the microscopic agglutination test against eight serovars of Leptospira interrogans including L grippotyphosa. Raccoons were trapped using Tomahawk live traps, anaesthetized with intramuscular injection of ketamine and acepromazine, bled by cardiac puncture and released. RESULTS: Forty-two raccoons were trapped in Middlesex (n=36) and Kent counties (n=6) from April 25 to May 2, 1998, and 10 (23.8%) of these animals had antibodies to L grippotyphosa. CONCLUSIONS: Infections due to L grippotyphosa or a closely related serovar are a risk for trappers in Ontario, and raccoons are a likely reservoir of this bacterium. PMID:18159265

  8. Effect of conduction band non-parabolicity on the optical gain of quantum cascade lasers based on the effective two-band finite difference method

    NASA Astrophysics Data System (ADS)

    Cho, Gookbin; Kim, Jungho

    2017-09-01

    We theoretically investigate the effect of conduction band non-parabolicity (NPB) on the optical gain spectrum of quantum cascade lasers (QCLs) using the effective two-band finite difference method. Based on the effective two-band model to consider the NPB effect in the multiple quantum wells (QWs), the wave functions and confined energies of electron states are calculated in two different active-region structures, which correspond to three-QW single-phonon and four-QW double-phonon resonance designs. In addition, intersubband optical dipole moments and polar-optical-phonon scattering times are calculated and compared without and with the conduction band NPB effect. Finally, the calculation results of optical gain spectra are compared in the two QCL structures having the same peak gain wavelength of 8.55 μm. The gain peaks are greatly shifted to longer wavelengths and the overall gain magnitudes are slightly reduced when the NPB effect is considered. Compared with the three-QW active-region design, the redshift of the peak gain is more prominent in the four-QW active-region design, which makes use of higher electronic states for the lasing transition.

  9. Diffusion-weighted MR imaging of the liver at 3.0 Tesla using TRacking Only Navigator echo (TRON): a feasibility study.

    PubMed

    Ivancevic, Marko K; Kwee, Thomas C; Takahara, Taro; Ogino, Tetsuo; Hussain, Hero K; Liu, Peter S; Chenevert, Thomas L

    2009-11-01

    To assess the feasibility of TRacking Only Navigator echo (TRON) for diffusion-weighted magnetic resonance imaging (DWI) of the liver at 3.0T. Ten volunteers underwent TRON, respiratory triggered, and free breathing DWI of the liver at 3.0 Tesla (T). Scan times were measured. Image sharpness, degree of stair-step and stripe artifacts for the three methods were assessed by two observers. Mean scan times of TRON and respiratory triggered DWI relative to free breathing DWI were 34% and 145% longer respectively. In four of eight comparisons (two observers, two b-values, two slice orientations), TRON DWI image sharpness was significantly better than free breathing DWI, but inferior to respiratory triggered DWI. In two of four comparisons (two observers, two b-values), degree of stair-step artifacts in TRON DWI was significantly lower than in respiratory triggered DWI. Degree of stripe artifacts between the three methods was not significantly different. DWI of the liver at 3.0T using TRON is feasible. Image sharpness in TRON DWI is superior to that in free breathing DWI. Although image sharpness of respiratory triggered DWI is still better, TRON DWI requires less scan time and reduces stair-step artifacts.

  10. A novel channel selection method for optimal classification in different motor imagery BCI paradigms.

    PubMed

    Shan, Haijun; Xu, Haojie; Zhu, Shanan; He, Bin

    2015-10-21

    For sensorimotor rhythms based brain-computer interface (BCI) systems, classification of different motor imageries (MIs) remains a crucial problem. An important aspect is how many scalp electrodes (channels) should be used in order to reach optimal performance classifying motor imaginations. While the previous researches on channel selection mainly focus on MI tasks paradigms without feedback, the present work aims to investigate the optimal channel selection in MI tasks paradigms with real-time feedback (two-class control and four-class control paradigms). In the present study, three datasets respectively recorded from MI tasks experiment, two-class control and four-class control experiments were analyzed offline. Multiple frequency-spatial synthesized features were comprehensively extracted from every channel, and a new enhanced method IterRelCen was proposed to perform channel selection. IterRelCen was constructed based on Relief algorithm, but was enhanced from two aspects: change of target sample selection strategy and adoption of the idea of iterative computation, and thus performed more robust in feature selection. Finally, a multiclass support vector machine was applied as the classifier. The least number of channels that yield the best classification accuracy were considered as the optimal channels. One-way ANOVA was employed to test the significance of performance improvement among using optimal channels, all the channels and three typical MI channels (C3, C4, Cz). The results show that the proposed method outperformed other channel selection methods by achieving average classification accuracies of 85.2, 94.1, and 83.2 % for the three datasets, respectively. Moreover, the channel selection results reveal that the average numbers of optimal channels were significantly different among the three MI paradigms. It is demonstrated that IterRelCen has a strong ability for feature selection. In addition, the results have shown that the numbers of optimal channels in the three different motor imagery BCI paradigms are distinct. From a MI task paradigm, to a two-class control paradigm, and to a four-class control paradigm, the number of required channels for optimizing the classification accuracy increased. These findings may provide useful information to optimize EEG based BCI systems, and further improve the performance of noninvasive BCI.

  11. Viral Hepatitis

    MedlinePlus

    ... vaccines protect you? During your lifetime, you need: One series of the hepatitis A vaccine (two shots given at least 6 months apart) One series of the hepatitis B vaccine (three or four shots given over a 6-month period) Most people ...

  12. Functional requirements for a comprehensive transportation location referencing system

    DOT National Transportation Integrated Search

    2000-06-01

    Transportation agencies manage data that is referenced in one, two, three, and four dimensions. Location referencing system (LRS) data models vary across transportation agencies and often within organizations as well. This has resulted in failed atte...

  13. Exotic particles with four or more quarks

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Olsen, Stephen Lars

    The familiar denizens of the particle zoo are made of two or three quarks, but particle theory allows for states comprising any number of those fundamental particles. Finally, after decades of searching, tetraquarks seem to have been spotted.

  14. Electric Propulsion for Low Earth Orbit Constellations

    NASA Technical Reports Server (NTRS)

    Oleson, Steven R.; Sankovic, John M.

    1998-01-01

    Hall Effect electric propulsion was evaluated for orbit insertion, satellite repositioning, orbit maintenance and de-orbit applications for a sample low earth orbit satellite constellation. Since the low masses of these satellites enable multiple spacecraft per launch, the ability to add spacecraft to a given launch was used as a figure of merit. When compared to chemical propulsion, the Hall thruster system can add additional spacecraft per launch using planned payload power levels. One satellite can be added to the assumed four satellite baseline chemical launch without additional mission times. Two or three satellites may be added by providing part of the orbit insertion with the Hall system. In these cases orbit insertion times were found to be 35 and 62 days. Depending on the electric propulsion scenario, the resulting launch vehicle savings is nearly two, three or four Delta 7920 launch vehicles out of the chemical baseline scenarios eight Delta 7920 launch vehicles.

  15. Electric Propulsion for Low Earth Orbit Constellations

    NASA Technical Reports Server (NTRS)

    Oleson, Steven R.; Sankovic, John M.

    1998-01-01

    Hall effect electric propulsion was evaluated for orbit insertion, satellite repositioning, orbit maintenance and de-orbit applications for a sample low earth orbit satellite constellation. Since the low masses of these satellites enable multiple spacecraft per launch, the ability to add spacecraft to a given launch was used as a figure of merit. When compared to chemical propulsion, the Hall thruster system can add additional spacecraft per launch using planned payload power levels. One satellite can be added to the assumed four satellite baseline chemical launch without additional mission times. Two or three satellites may be added by providing part of the orbit insertion with the Hall system. In these cases orbit insertion times were found to be 35 and 62 days. Depending, on the electric propulsion scenario, the resulting launch vehicle savings is nearly two, three or four Delta 7920 launch vehicles out of the chemical baseline scenario's eight Delta 7920 launch vehicles.

  16. Diarrheal and Respiratory Illness Surveillance During US-RP Balikatan 2014.

    PubMed

    Velasco, John M; Valderamat, Maria T; Nogrado, Kathyleen; Wongstitwilairoong, Tippa; Swierczewski, Brett; Bodhidatta, Ladaporn; Lertsethtakarn, Paphavee; Klungthong, Chonticha; Fernandez, Stefan; Mason, Carl; Yoon, In-Kyu; Macareo, Louis

    2015-06-01

    Diarrheal and respiratory illness surveillance was conducted during the 2014 Republic of the Philippines-U.S. Exercise Balikatan in the Philippines. Seven stool and three respiratory specimens that met the inclusion criteria were collected. Diarrhea stool specimens were tested with commercial enzyme-linked immunosorbent assay kits and real-time polymerase chain reaction (PCR) for 12 viral, bacterial, and protozoan pathogens. Campylobacter, enterotoxigenic Escherichia coli (ETEC), and enteropathogenic Escherichia coli (EPEC) were detected in four of seven (57%), two of seven (29%), and four of seven (57%) specimens, respectively. There were co-infections of EPEC and ETEC in two cases and EPEC and Campylobacter spp. in one case. Respiratory samples were tested using RT-PCR. One of three samples was positive for influenza B. Laboratory-based surveillance is important in determining causative agents for illnesses experienced by military personnel during deployment. Development of vaccines for enteric diseases should be expedited to mitigate their impact on operational readiness.

  17. An examination of the factor structure of the Sociocultural Attitudes Towards Appearance Questionnaire-3 in Malaysia.

    PubMed

    Swami, Viren

    2009-03-01

    The present study examined the factor structure of a Malay translation of the Sociocultural Attitudes Towards Appearance Questionnaire-3 among a community sample of 554 Malaysian women. Results of an exploratory factor analysis revealed the existence of four factors, two of which (Information and Internalization-Athlete) mirrored those found among Western samples. An additional factor was an amalgamation of two factors reported in the West, namely Pressure and Internalization-General. A fourth factor consisted of six items, four of which cross-loaded onto previous factors, and was consequently dropped from analyses. Cronbach's alpha coefficients for the three retained factors were all above .82, and the three factors were significantly correlated with each other and with participants' body mass index. The results of this study stress the need for locally developed scales in the study of body image and a shift away from reliance on scales developed in the West.

  18. Cluster of atypical adult Guillain-Barré syndrome temporally associated with neurological illness due to EV-D68 in children, South Wales, United Kingdom, October 2015 to January 2016.

    PubMed

    Williams, Christopher J; Thomas, Rhys H; Pickersgill, Trevor P; Lyons, Marion; Lowe, Gwen; Stiff, Rhianwen E; Moore, Catherine; Jones, Rachel; Howe, Robin; Brunt, Huw; Ashman, Anna; Mason, Brendan W

    2016-01-01

    We report a cluster of atypical Guillain-Barré syndrome in 10 adults temporally related to a cluster of four children with acute flaccid paralysis, over a 3-month period in South Wales, United Kingdom. All adult cases were male, aged between 24 and 77 years. Seven had prominent facial diplegia at onset. Available electrophysiological studies showed axonal involvement in five adults. Seven reported various forms of respiratory disease before onset of neurological symptoms. The ages of children ranged from one to 13 years, three of the four were two years old or younger. Enterovirus testing is available for three children; two had evidence of enterovirus D68 infection in stool or respiratory samples. We describe the clinical features, epidemiology and state of current investigations for these unusual clusters of illness.

  19. Group B streptococcal arthritis in adults.

    PubMed

    Small, C B; Slater, L N; Lowy, F D; Small, R D; Salvati, E A; Casey, J I

    1984-03-01

    Group B streptococcal arthritis in adults is uncommon. This report describes seven cases seen at these institutions over the past five years and reviews the previous 17 documented cases. Of seven adults, three were diabetics, three had prosthetic hips, and one had undergone splenectomy. Six had undergone no prior dental, genitourinary, or gastrointestinal procedures. The most common clinical presentation was fever and acute joint pain. Five patients had monoarticular arthritis; two had multiple joint involvement. Underlying joint abnormalities included osteoarthritis (two), prosthetic hip (three), and neuropathic joint (one). Bacteremia was documented in three and suspected in the remaining four patients, often without a primary source. Therapy included parenteral antibiotics, usually penicillin G, and drainage of the involved joint. Two of three patients with prosthetic implants required Girdlestone procedures; the third was apparently cured. The three diabetic patients died, one with resolution of group B streptococcal arthritis. The seventh patient was cured. Group B streptococcal arthritis is a serious infection in adults with diabetes and late prosthetic hip infections.

  20. Study of degenerate four-quark states with SU(2) lattice Monte Carlo techniques

    NASA Astrophysics Data System (ADS)

    Green, A. M.; Lukkarinen, J.; Pennanen, P.; Michael, C.

    1996-01-01

    The energies of four-quark states are calculated for geometries in which the quarks are situated on the corners of a series of tetrahedra and also for geometries that correspond to gradually distorting these tetrahedra into a plane. The interest in tetrahedra arises because they are composed of three degenerate partitions of the four quarks into two two-quark color singlets. This is an extension of earlier work showing that geometries with two degenerate partitions (e.g., squares) experience a large binding energy. It is now found that even larger binding energies do not result, but that for the tetrahedra the ground and first excited states become degenerate in energy. The calculation is carried out using SU(2) for static quarks in the quenched approximation with β=2.4 on a 163×32 lattice. The results are analyzed using the correlation matrix between different Euclidean times and the implications of these results are discussed for a model based on two-quark potentials.

  1. The Meteoritical Bulletin, No. 92, 2007 September

    NASA Astrophysics Data System (ADS)

    Connolly, Harold C.; Smith, Caroline; Benedix, Gretchen; Folco, Luigi; Righter, Kevin; Zipfel, Jutta; Yamaguchi, Akira; Aoudjehane, Hasnaa Chennaoui

    In this editon of The Meteoritical Bulletin, 1394 recognized meteorites are reported, 27 from specific locations within Africa, 133 from Northwest Africa, 1227 from Antartica (from ANSMET, PNRA, and PRIC expeditions), and 7 from Asia. The Meteoritical Bulletin announces the approval of four new names series by the Nomenclature Committee of the Meteoritical Society, two from Africa and one from Asia, including Al Haggounia, from Al Haggounia, Morocco, which is projected to be on the order of 3 metric tons of material related to enstatite chondrites and aubrites. Approved are two falls from Africa, Bassikounou (Mauretania) and Gashua (Nigeria). Approved from areas other than Antarctica are one lunar, two Martian, 32 other achondrites, three mesosiderites, two pallasites, one CM, two CK, one CR2, two CV3, one CR2, and four R chondrites. The Nomenclature Committee of the Meteoritical Society 48 newly approved relict meteorites from two new name series, Österplana and Gullhögen (both from Sweden).

  2. Effects of Intra- and Interpatch Host Density on Egg Parasitism by Three Species of Trichogramma

    PubMed Central

    Grieshop, Matthew J.; Flinn, Paul W.; Nechols, James R.

    2010-01-01

    Host-foraging responses to different intra- and interpatch densities were used to assess three Trichogramma spp. (Hymenoptera: Trichogrammatidae) Trichogramma deion Pinto and Oatman, T. ostriniae Pang and Chen, and T. pretiosum Riley — as potential biological control agents for the Indian meal moth, Plodia interpunctella Hübner (Lepidoptera: Pyralidae). Single naïve females were allowed 6 h to forage in Plexiglas arenas with four different spatial arrangements of host eggs, nine single-egg patches), nine four-egg patches, 36 single-egg patches, and 36 four-egg patches. No significant differences were found among species in the number of patches parasitized. As expected, all three species parasitized the most eggs in the 36 four-egg patch treatment and the least in the nine single-egg patch treatment. T. deion parasitized significantly more eggs than T. pretiosum on the nine four-egg patches. T. ostriniae parasitized significantly more patches when intrapatch density was greater, regardless of interpatch density. In contrast, T. deion only parasitized more patches at the greater intrapatch density when the interpatch density was low. Patch density had no effect on T. pretiosum. The spatial pattern of parasitism was more aggregated for T. deion and T. ostriniae in the 36 four-egg patches treatment compared to the 36 single-egg patches treatment. Therefore, intrapatch density was more important than interpatch density for T. ostriniae, and potentially for T. deion, but not for T. pretiosum. T. deion may be the best candidate for augmentative biological control because it parasitized either slightly or significantly more eggs than the other two species in all four treatments. Furthermore, the pattern of parasitism by T. deion in the 36 four-egg patches treatment was the most aggregated among the three species, suggesting a more thorough searching pattern. In contrast, T. pretiosum had the least aggregated pattern of parasitism and therefore may have used a more random foraging pattern. PMID:20673123

  3. Effects of intra- and interpatch host density on egg parasitism by three species of Trichogramma.

    PubMed

    Grieshop, Matthew J; Flinn, Paul W; Nechols, James R

    2010-01-01

    Host-foraging responses to different intra- and interpatch densities were used to assess three Trichogramma spp. (Hymenoptera: Trichogrammatidae) Trichogramma deion Pinto and Oatman, T. ostriniae Pang and Chen, and T. pretiosum Riley - as potential biological control agents for the Indian meal moth, Plodia interpunctella Hübner (Lepidoptera: Pyralidae). Single naïve females were allowed 6 h to forage in Plexiglas arenas with four different spatial arrangements of host eggs, nine single-egg patches), nine four-egg patches, 36 single-egg patches, and 36 four-egg patches. No significant differences were found among species in the number of patches parasitized. As expected, all three species parasitized the most eggs in the 36 four-egg patch treatment and the least in the nine single-egg patch treatment. T. deion parasitized significantly more eggs than T. pretiosum on the nine four-egg patches. T. ostriniae parasitized significantly more patches when intrapatch density was greater, regardless of interpatch density. In contrast, T. deion only parasitized more patches at the greater intrapatch density when the interpatch density was low. Patch density had no effect on T. pretiosum. The spatial pattern of parasitism was more aggregated for T. deion and T. ostriniae in the 36 four-egg patches treatment compared to the 36 single-egg patches treatment. Therefore, intrapatch density was more important than interpatch density for T. ostriniae, and potentially for T. deion, but not for T. pretiosum. T. deion may be the best candidate for augmentative biological control because it parasitized either slightly or significantly more eggs than the other two species in all four treatments. Furthermore, the pattern of parasitism by T. deion in the 36 four-egg patches treatment was the most aggregated among the three species, suggesting a more thorough searching pattern. In contrast, T. pretiosum had the least aggregated pattern of parasitism and therefore may have used a more random foraging pattern.

  4. The important role of co-infections in patients with AIDS and progressive disseminated histoplasmosis (PDH): A cohort from Colombia.

    PubMed

    Caceres, Diego H; Tobón, Ángela M; Restrepo, Ángela; Chiller, Tom; Gómez, Beatriz L

    2018-03-01

    A total of 23/45 (51%) patients with AIDS and histoplasmosis from Medellín, Colombia had other infections. Tuberculosis was the most common (n = 16/23, 70%). Pneumocystosis and cryptococcosis were found in three patients each (13%), bacterial infection and cytomegalovirus occurred each in two patients (9%) while toxoplasmosis, herpes virus and esophageal candidiasis were recorded in one patient each (4%). Of all co-infected patients, 18/23 (78%) had one, four (17%) had two and one (4%) had three additional opportunistic infections.

  5. Correlation of heart rate/ST slope and coronary angiographic findings.

    PubMed Central

    Balcon, R; Brooks, N; Layton, C

    1984-01-01

    The heart rate/ST slope was evaluated in 49 patients undergoing routine investigation for possible coronary artery disease. The slope correctly predicted the absence of any 75% stenoses in the seven patients to whom this applied; it was, however, correct for only four of 30 with one stenosis, one of 10 with two, and neither of the patients with three. Distinct slope ranges were not found, and the previously published ranges said to be specific for no significant stenosis and one, two, and three vessel disease were not. PMID:6466516

  6. On low-energy effective action in three-dimensional = 2 and = 4 supersymmetric electrodynamics

    NASA Astrophysics Data System (ADS)

    Buchbinder, I. L.; Merzlikin, B. S.; Samsonov, I. B.

    2013-11-01

    We discuss general structure of low-energy effective actions in = 2 and = 4 three-dimensional supersymmetric electrodynamics (SQED) in gauge superfield sector. There are specific terms in the effective action having no four-dimensional analogs. Some of these terms are responsible for the moduli space metric in the Coulomb branch of the theory. We find two-loop quantum corrections to the moduli space metric in the = 2 SQED and show that in the = 4 SQED the moduli space does not receive two-loop quantum corrections.

  7. Physics Practical Work and Its Influence on Students' Academic Achievement

    ERIC Educational Resources Information Center

    Musasia, Amadalo Maurice; Ocholla, Alphayo Abacha; Sakwa, Thomas Welikhe

    2016-01-01

    In Kenyan secondary schools, form two is an important class for all students. The students choose relevant subjects to study in form three and four. Physics is compulsory at form one and two but optional thereafter. Performance in the subject at the end of the secondary school is usually dismal. Majority of students lack motivation for most…

  8. Shock Equation of State of Multi-Phase Epoxy-Based Composite (Al-MnO2-Epoxy)

    DTIC Science & Technology

    2010-10-01

    single stage light gas gun , two...using three different loading techniques— single stage light gas gun , two stage light gas gun , and explosive loading—with multiple diagnostic...wave speed. B. Single stage gas gun loading experiments Four gas gun -driven equation of state experiments were conducted at NSWC-Indian Head using

  9. The Robustness of Pre-School Children's Tendency to Count Discrete Physical Objects

    ERIC Educational Resources Information Center

    Fletcher, Ben; Pine, Karen J.

    2009-01-01

    When pre-school children count an array of objects containing one that is broken in half, most count the halves as two separate objects. Two studies explore this predisposition to count discrete physical objects (DPOs) and investigate its robustness in the face of various manipulations. In Experiment 1, 32 children aged three-four years counted…

  10. Effects of Elicitation Procedures on the Narratives of Normal and Closed Head-Injured Adults.

    ERIC Educational Resources Information Center

    Liles, Betty Z.; And Others

    1989-01-01

    Twenty-three normal adults and four closed head-injured (CHI) adults with a high level of language recovery retold and generated stories. The two tasks differentially influenced the performance of both groups. The two groups differed in measures of cohesiveness and story grammar only in the story generation task. (Author/JDD)

  11. Look Before You Leap: Fables for the Elementary Level.

    ERIC Educational Resources Information Center

    Pillar, Arlene M.

    To demonstrate the inappropriateness of fables for moral instruction at early elementary levels, a study was conducted with children from grades two, four, and six in two suburban schools on Long Island (New York). The children listened to recordings of three fables, "The Shepherd Boy and the Wolf,""The Fox and the Goat," and "The Lion and the…

  12. 25 CFR 91.3 - Description of village reserves.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    .... twenty-two (22), all in township twenty-four (24) north, range six (6) east of the Indian meridian, and... Half (E 1/2) of the Southwest Quarter (SW 1/4) of Section Six (6) in Township Twenty-two (22) North... Three (3) in Township Twenty-five (25) North, Range Nine (9) East of the Indian Meridian, and containing...

  13. 25 CFR 91.3 - Description of village reserves.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .... twenty-two (22), all in township twenty-four (24) north, range six (6) east of the Indian meridian, and... Half (E 1/2) of the Southwest Quarter (SW 1/4) of Section Six (6) in Township Twenty-two (22) North... Three (3) in Township Twenty-five (25) North, Range Nine (9) East of the Indian Meridian, and containing...

  14. Clinical considerations and key issues in the management of patients with Erdheim-Chester Disease: a seven case series.

    PubMed

    Mazor, Roei D; Manevich-Mazor, Mirra; Kesler, Anat; Aizenstein, Orna; Eshed, Iris; Jaffe, Ronald; Pessach, Yakov; Goldberg, Ilan; Sprecher, Eli; Yaish, Iris; Gural, Alexander; Ganzel, Chezi; Shoenfeld, Yehuda

    2014-12-01

    Erdheim-Chester Disease (ECD), a non Langerhans' cell histiocytosis of orphan nature and propensity for multi-systemic presentations, comprises an intricate medical challenge in terms of diagnosis, treatment and complication management. The objectives are to report the clinical, radiological and pathological characteristics, as well as cardinal therapeutic approaches to ECD patients and to provide clinical analyses of the medical chronicles of these complex patients. Patients with biopsy proven ECD were audited by a multi-disciplinary team of specialists who formed a coherent timeline of all the substantial clinical events in the evolution of their patients' illness. Seven patients (five men, two women) were recruited to the study. The median age at presentation was 53 years (range: 39 to 62 years). The median follow-up time was 36 months (range: 1 to 72 months). Notable ECD involvement sites included the skeleton (seven), pituitary gland (seven), retroperitoneum (five), central nervous system (four), skin (four), lungs and pleura (four), orbits (three), heart and great vessels (three) and retinae (one). Prominent signs and symptoms were fever (seven), polyuria and polydipsia (six), ataxia and dysarthria (four), bone pain (four), exophthalmos (three), renovascular hypertension (one) and dyspnea (one). The V600E BRAF mutation was verified in three of six patients tested. Interferon-α treatment was beneficial in three of six patients treated. Vemurafenib yielded dramatic neurological improvement in a BRAF mutated patient. Infliximab facilitated pericardial effusion volume reduction. Cladribine improved cerebral blood flow originally compromised by perivenous lesions. ECD is a complex, multi-systemic, clonal entity coalescing both neoplastic and inflammatory elements and strongly dependent on impaired RAS/RAF/MEK/ERK signaling.

  15. Comparison of three-way and four-way calibration for the real-time quantitative analysis of drug hydrolysis in complex dynamic samples by excitation-emission matrix fluorescence.

    PubMed

    Yin, Xiao-Li; Gu, Hui-Wen; Liu, Xiao-Lu; Zhang, Shan-Hui; Wu, Hai-Long

    2018-03-05

    Multiway calibration in combination with spectroscopic technique is an attractive tool for online or real-time monitoring of target analyte(s) in complex samples. However, how to choose a suitable multiway calibration method for the resolution of spectroscopic-kinetic data is a troubling problem in practical application. In this work, for the first time, three-way and four-way fluorescence-kinetic data arrays were generated during the real-time monitoring of the hydrolysis of irinotecan (CPT-11) in human plasma by excitation-emission matrix fluorescence. Alternating normalization-weighted error (ANWE) and alternating penalty trilinear decomposition (APTLD) were used as three-way calibration for the decomposition of the three-way kinetic data array, whereas alternating weighted residual constraint quadrilinear decomposition (AWRCQLD) and alternating penalty quadrilinear decomposition (APQLD) were applied as four-way calibration to the four-way kinetic data array. The quantitative results of the two kinds of calibration models were fully compared from the perspective of predicted real-time concentrations, spiked recoveries of initial concentration, and analytical figures of merit. The comparison study demonstrated that both three-way and four-way calibration models could achieve real-time quantitative analysis of the hydrolysis of CPT-11 in human plasma under certain conditions. However, it was also found that both of them possess some critical advantages and shortcomings during the process of dynamic analysis. The conclusions obtained in this paper can provide some helpful guidance for the reasonable selection of multiway calibration models to achieve the real-time quantitative analysis of target analyte(s) in complex dynamic systems. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Diverse Mesorhizobium bacteria nodulate native Astragalus and Oxytropis in arctic and subarctic areas in Eurasia.

    PubMed

    Ampomah, Osei Yaw; Mousavi, Seyed Abdollah; Lindström, Kristina; Huss-Danell, Kerstin

    2017-01-01

    Rhizobia nodulating native Astragalus and Oxytropis spp. in Northern Europe are not well-studied. In this study, we isolated bacteria from nodules of four Astragalus spp. and two Oxytropis spp. from the arctic and subarctic regions of Sweden and Russia. The phylogenetic analyses were performed by using sequences of three housekeeping genes (16S rRNA, rpoB and recA) and two accessory genes (nodC and nifH). The results of our multilocus sequence analysis (MLSA) of the three housekeeping genes tree showed that all the 13 isolates belonged to the genus Mesorhizobium and were positioned in six clades. Our concatenated housekeeping gene tree also suggested that the isolates nodulating Astragalus inopinatus, Astragalus frigidus, Astragalus alpinus ssp. alpinus and Oxytropis revoluta might be designated as four new Mesorhizobium species. The 13 isolates were grouped in three clades in the nodC and nifH trees. 15 N analysis suggested that the legumes in association with these isolates were actively fixing nitrogen. Copyright © 2016 Elsevier GmbH. All rights reserved.

  17. Four linked outbreaks of Salmonella enteritidis phage type 4 infection--the continuing egg threat.

    PubMed

    Ejidokun, O O; Killalea, D; Cooper, M; Holmyard, S; Cross, A; Kemp, C

    2000-06-01

    Four outbreaks of Salmonella enteritidis phage type (PT) 4 occurred among guests at functions for which a single commercial caterer supplied food. Retrospective cohort studies were used to describe the epidemiology of three of these outbreaks and identify the vehicle(s) responsible. Of 172 guests at these three events, 47 fitted the clinical case definition for illness and 24 cases were confirmed to have S. enteritidis PT4 infection. Food containing raw egg was identified epidemiologically as the likely vehicle of infection in two of the three outbreaks (odds ratios (OR) and 95% confidence intervals 9.1 (2.2-39.9) and 6.9 (1.2-46.4)). Logistic regression analysis yielded OR = 10.7 (p = 0.0022) and OR = 9.3 (p = 0.015) for egg consumption in two of the outbreaks. These outbreaks highlighted the continuing need to remind the public and commercial caterers of the potential high risks of contracting salmonella from shell eggs. Education of caterers includes advice to obtain eggs and other products from reputable and identifiable suppliers.

  18. A diketiminate-bound diiron complex with a bridging carbonate ligand

    PubMed Central

    Sadique, Azwana R.; Brennessel, William W.; Holland, Patrick L.

    2009-01-01

    Reduction of carbon dioxide by a diiron(I) complex gives μ-carbonato-κ3 O:O′,O′′-bis­{[2,2,6,6-tetra­methyl-3,5-bis­(2,4,6-triisopropyl­phenyl)heptane-2,5-diiminate(1−)-κ2 N,N′]iron(II)} toluene disolvate, [Fe2(C41H65N)2(CO3)]·2C7H8, a diiron(II) species with a bridging carbonate ligand. The asymmetric unit contains one diiron complex and two cocrystallized toluene solvent mol­ecules that are distributed over three sites, one with atoms in general positions and two in crystallographic sites. Both FeII atoms are η2-coordinated to diketiminate ligands, but η1- and η2-coordinated to the bridging carbonate ligand. Thus, one FeII center is three-coordinate and the other is four-coordinate. The bridging carbonate ligand is nearly perpendicular to the iron–diketiminate plane of the four-coordinate FeII center and parallel to the plane of the three-coordinate FeII center. PMID:19407402

  19. Clinical and angioarchitectural factors influencing the endovascular approach to galenic dural arteriovenous fistulas in adults: case series and review of the literature.

    PubMed

    Cohen, José E; Gomori, John Moshe; Rajz, Gustavo; Paldor, Iddo; Moscovici, Samuel; Itshayek, Eyal

    2017-05-01

    Galenic dural arteriovenous fistulas (DAVF) are rare; however, they are the most frequent type of DAVF to manifest aggressive clinical behavior and usually represent a diagnostic and therapeutic challenge for clinicians. We retrospectively reviewed clinical and imaging data of patients managed with neuroendovascular techniques for the treatment of galenic DAVFs from 2000 to 2016. We searched the 2000-2016 English-language literature for papers discussing neuroendovascular management of galenic DAVFs, with or without companion surgical procedures. Five patients were treated for galenic DAVFs during the study period (four males; mean age, 61 years). Three presented with progressive neurological deterioration due to venous congestion, two with acute intracranial hemorrhage. Three were treated by staged transarterial embolization procedures (three procedures in two, four procedures in one); two underwent a single transvenous embolization procedure. Four out of five fistulas were completely occluded. All patients improved clinically; the patient whose fistula was partially occluded remains angiographically stable at 2-year follow-up. Six reports describing 17 patients are reviewed. Embolization was performed via transvenous approach in 1/17 and transarterial approach in 16/17 with additional open surgery in 9/16. The trend toward the use of transarterial approaches is based primarily on advances on embolization techniques that allow better and more controllable penetration of the embolizing agents with improved clinical and angiographic results, as well as the technical complexity of the transvenous approach. Although transarterial embolization is the preferred endovascular route for the management of most galenic DAVFs, selected cases can be successfully treated by transvenous approach.

  20. Influence of the four-photon parametric processes and cross-phase modulation on the relative motion of optical filaments

    NASA Astrophysics Data System (ADS)

    Kovachev, L. M.; Georgieva, D. A.; Dakova, A. M.

    2015-10-01

    We investigate two types of nonlinear interaction between collinear femtosecond laser pulses with power slightly above the critical for self-focusing {{P}\\text{cr}} . In the first case we study energy exchange between filaments. The model describes this process through a degenerate four-photon parametric mixing (FPPM) scheme and requests initial phase difference between the waves. When there is no initial phase difference between the pulses, the FPPM process does not work. In this case the second type of interaction is obtained as merging between two, three or four filaments in a single filament with higher power. It is found that in the second case the interflow between the filaments has the potential for interaction due to cross-phase modulation (CPM).

  1. Population growth and development of Liposcelis pearmani (Psocoptera: Liposcelididae) at constant temperatures and relative humidities.

    PubMed

    Aminatou, B A; Gautam, S G; Opit, G P; Talley, J; Shakya, K

    2011-08-01

    Psocids of genus Liposcelis are now considered serious pests of stored products. We investigated the effects of eight temperatures (22.5, 25.0, 27.5, 30.0, 32.5, 35.0, 37.5, and 40.0°C) and four relative humidities (43, 55, 63, and 75%) on population growth and development of the psocid Liposcelis pearmani Lienhard. L. pearmani did not survive at 37.5 and 40.0°C, at all relative humidities tested; at 43% RH, at all temperatures tested; and at 55% RH, at 32.5 and 35°C. The greatest population growth was recorded at 32.5°C and 75% RH (32-fold growth). L. pearmani males have two to four nymphal instars, and the percentages of males with two, three, and four instars were 17, 63, and 20%, respectively. Female L. pearmani have two to five instars, and the percentages of females with two, three, four, and five instars were 5, 39, 55, and 1%, respectively. We developed temperature-dependent development equations for male and female eggs, individual nymphal, combined nymphal, and combined immature stages. Based on 30-d population growth, L. pearmani cannot survive at temperatures >35.0°C; does not thrive at low relative humidities (55%), at temperatures above 25°C; and has a high optimum relative humidity for population growth (75%). Therefore, we expect it to have a more limited distribution compared with other Liposcelis species. These data provide a better understanding of how temperature and RH may influence L. pearmani population dynamics and can be used in population growth models to help develop effective management strategies for this psocid, and to predict its occurrence.

  2. Polymeric Cd(II), trinuclear and mononuclear Ni(II) complexes of 5-methyl-4-phenyl-1,2,4-triazole-3-thione: Synthesis, structural characterization, thermal behaviour, fluorescence properties and antibacterial activity

    NASA Astrophysics Data System (ADS)

    Bharty, M. K.; Paswan, S.; Dani, R. K.; Singh, N. K.; Sharma, V. K.; Kharwar, R. N.; Butcher, R. J.

    2017-02-01

    Syntheses of a polymeric Cd(II) complex, [Cd(mptt)2]n (1), a trinuclear Ni(II) complex, [Ni3(μ-mptt)4(μ-H2O)2(H2O)2(ttfa)2]·3H2O (2) and a mononuclear Ni(II) complex [Ni(mptt)2(en)2] (3) have been performed using the ligand 5-methyl-4-phenyl-1,2,4-triazole-3-thione (Hmptt) and nickel(II)/cadmium(II) salts {ttfa = thenoyltrifluroacetonate). The ligand and the complexes have been characterized by various physicochemical methods in addition to their single crystal X-ray structure. The Cd centre in complex 1 adopts a distorted tetrahedral geometry with one sulfur atom and two mptt ligands provide three nitrogen atoms from three triazole units. The sulfur atom of the ligand binds covalently and overall the ligand acts as uninigative N,S/N,N bidentate moiety. The polymeric structure of complex 1 results from the N atoms of the neighboring triazole units coordinating with the Cd(II) centre. The three Ni(II) centres in the trinuclear Ni(II) complex 2 form a linear arrangement and all have six coordinated arrangements. The middle Ni(II) binds with four deprotonated triazole ring nitrogens and two water molecules form two bridges. The terminal Ni(II) centres bind through two thenoyl oxygens, two triazole nitrogens and water molecules that formed bridges with the middle Ni centre. In complex 3, the nickel(II) centre is covalently bonded through two deprotonated triazole ring nitrogens from two ligand moieties and other four sites are occupied by four nitrogens from two bidentate en ligands. Thermogravimetric analyses (TGA) of the complexes indicated for NiO as the final residue. The bioefficacy of the ligand and complexes 2 and 3 have been examined against the growth of bacteria to evaluate their anti-microbial potential. Complex 2 showed high antibacterial activity as compared to the ligand and complex 3. Complexes 1, 2 and 3 are fluorescent materials with maximum emissions at 425, 421 and 396 nm at an excitation wavelength of 323, 348 and 322 nm, respectively.

  3. Adipogenesis in thyroid eye disease.

    PubMed

    Crisp, M; Starkey, K J; Lane, C; Ham, J; Ludgate, M

    2000-10-01

    Adipogenesis contributes to the pathogenesis of thyroid eye disease (TED). Thyrotropin receptor (TSHR) transcripts are present in orbital fat. This study was conducted to determine whether they are expressed as functional protein, and if so, whether this is restricted to TED orbits or to a particular stage in adipocyte differentiation. Samples of fat were obtained from 18 TED-affected orbits and 4 normal orbits, and 9 were obtained from nonorbital locations. Frozen sections were examined by immunocytochemistry using monoclonal antibodies specific for the human TSHR. Samples were disaggregated and the preadipocytes separated from the mature by differential centrifugation and cultured in serum-free or DM and examined for morphologic changes, oil red O and TSHR staining, and TSH-induced cyclic adenosine monophosphate (cAMP) production. Marked immunoreactivity was observed in frozen sections from all three TED samples and faint staining in both normal orbital fat samples. In vitro, 1% to 5% of preadipocytes displayed TSHR immunoreactivity in five of six TED and two of three normal orbital samples and in three of five nonorbital samples. Differentiation, was induced in all 14 orbital samples. Three of four nonorbital samples contained occasional differentiated cells. Fifty percent to 70% of differentiating cells demonstrated receptor immunoreactivity. Two of three TED and four of four nonorbital preadipocytes in DM and/or mature adipocytes displayed a TSH-mediated increase in cAMP. The results indicate that orbital fat TSHR transcripts are expressed as protein, which can be functional. This is not aberrant in TED orbits, although expression may be upregulated. The majority of preadipocytes undergoing differentiation express the receptor, indicating a key role for this population in one mechanism for increasing orbital volume.

  4. Four-year durability of clinical and haemodynamic outcomes of transcatheter aortic valve implantation with the self-expanding CoreValve.

    PubMed

    Gulino, Simona; Barbanti, Marco; Deste, Wanda; Immè, Sebastiano; Aruta, Patrizia; Bottari, Vera; Benvenuto, Emanuele; Tamburino, Claudia; Di Landro, Alessio; Liberto, Daria; Santonoceto, Letizia; Sicuso, Rita; Di Stefano, Daniele; Todaro, Denise; Di Simone, Emanuela; Indelicato, Antonino; Giannazzo, Daniela; Sgroi, Carmelo; Tamburino, Corrado

    2016-10-10

    Long-term data on the durability of currently available transcatheter heart valves are limited. We sought to assess four-year clinical and echocardiographic outcomes in patients undergoing transcatheter aortic valve implantation (TAVI) with the CoreValve prosthesis. Between June 2007 and February 2014, 450 consecutive patients with symptomatic severe aortic stenosis underwent TAVI in our institution. For the purposes of this study, we included only those patients undergoing successful TAVI with the CoreValve prosthesis who had a minimum follow-up of four years (n=125). Survival rates at one, two, three and four years were 83.2, 76.8, 73.6 and 66.3%, respectively. Aortic regurgitation was a common finding after the procedure, especially due to paravalvular regurgitation (PVR), which was observed in the majority of patients (71.5%), mostly mild (52.0%). Progression from mild acute PVR to moderate PVR at four-year follow-up was reported in three patients. No cases of severe PVR were observed. Prosthetic valve failure was reported in four patients (3.2%). Our study demonstrates that favourable outcomes after successful TAVI are associated with sustained clinical and functional cardiovascular benefits up to four-year follow-up. Signs of moderate prosthetic valve failure are present only in a small percentage of patients.

  5. von Kármán-Howarth equation for three-dimensional two-fluid plasmas.

    PubMed

    Andrés, N; Mininni, P D; Dmitruk, P; Gómez, D O

    2016-06-01

    We derive the von Kármán-Howarth equation for a full three-dimensional incompressible two-fluid plasma. In the long-time limit and for very large Reynolds numbers we obtain the equivalent of the hydrodynamic "four-fifths" law. This exact law predicts the scaling of the third-order two-point correlation functions, and puts a strong constraint on the plasma turbulent dynamics. Finally, we derive a simple expression for the 4/5 law in terms of third-order structure functions, which is appropriate for comparison with in situ measurements in the solar wind at different spatial ranges.

  6. Influence of implant number on the biomechanical behaviour of mandibular implant-retained/supported overdentures: a three-dimensional finite element analysis.

    PubMed

    Liu, Jingyin; Pan, Shaoxia; Dong, Jing; Mo, Zhongjun; Fan, Yubo; Feng, Hailan

    2013-03-01

    The aim of this study was to evaluate strain distribution in peri-implant bone, stress in the abutments and denture stability of mandibular overdentures anchored by different numbers of implants under different loading conditions, through three-dimensional finite element analysis (3D FEA). Four 3D finite element models of mandibular overdentures were established, using between one and four Straumann implants with Locator attachments. Three types of load were applied to the overdenture in each model: 100N vertical and inclined loads on the left first molar and a 100N vertical load on the lower incisors. The biomechanical behaviours of peri-implant bone, implants, abutments and overdentures were recorded. Under vertical load on the lower incisors, the single-implant overdenture rotated over the implant from side to side, and no obvious increase of strain was found in peri-implant bone. Under the same loading conditions, the two-implant-retained overdenture showed more apparent rotation around the fulcrum line passing through the two implants, and the maximum equivalent stress in the abutments was higher than in the other models. In the three-implant-supported overdenture, no strain concentration was found in cortical bone around the middle implant under three loading conditions. Single-implant-retained mandibular overdentures do not show damaging strain concentration in the bone around the only implant and may be a cost-effective treatment option for edentulous patients. A third implant can be placed between the original two when patients rehabilitated by two-implant overdentures report constant and obvious denture rotation around the fulcrum line. Copyright © 2012 Elsevier Ltd. All rights reserved.

  7. Optical coupling elements for coherent optical multiport receivers

    NASA Astrophysics Data System (ADS)

    Langenhorst, Ralf

    1992-05-01

    Three by three (3 by 3) and four by four (4 by 4) port coupling elements and receivers for heterodyne multiport systems are realized. Commercial (3 by 3) fiber coupling elements were used to achieve a usual (3 by 3) port receiver and a (3 by 3) port receiver in pushpull switching, whose concept was theoretically and experimentally analyzed. It is established that intensity oscillations of laser sources are suppressed by pushpull switching. The influence of thermal noise of opto-electronic input levels is shown to be weaker than in usual (3 by 3) port and (4 by 4) port receivers. Thermal noise effect in pushpull switching is similar to this one in heterodyne receivers. An integrated optical coupling element in LiNbO3 was made with bridge circuit from four waveguide coupling elements and two phase converters, which are electro-optically tunable so that a continuous regulation of intermediate frequency phase can be compensated by temperature variations of the element. To obtain fiber-to-fiber losses lower than a dB, a compact crystal optical coupling element was developed with reference to polarization properties of optical waves. This element supplied the eight necessary intermediate frequency output signals. A direct experimental comparison of bandwidth efficiency of multiport and heterodyne receivers shows a factor two in optical area and a factor three in electrical frequency area.

  8. Sorption behavior of 17 phthalic acid esters on three soils: effects of pH and dissolved organic matter, sorption coefficient measurement and QSPR study.

    PubMed

    Yang, Fen; Wang, Meng; Wang, Zunyao

    2013-09-01

    This work studies the sorption behaviors of phthalic acid esters (PAEs) on three soils by batch equilibration experiments and quantitative structure property relationship (QSPR) methodology. Firstly, the effects of soil type, dissolved organic matter and pH on the sorption of four PAEs (DMP, DEP, DAP, DBP) are investigated. The results indicate that the soil organic carbon content has a crucial influence on sorption progress. In addition, a negative correlation between pH values and the sorption capacities was found for these four PAEs. However, the effect of DOM on PAEs sorption may be more complicated. The sorption of four PAEs was promoted by low concentrations of DOM, while, in the case of high concentrations, the influence of DOM on the sorption was complicated. Then the organic carbon content normalized sorption coefficient (logKoc) values of 17 PAEs on three soils were measured, and the mean values ranged from 1.50 to 7.57. The logKoc values showed good correlation with the corresponding logKow values. Finally, two QSPR models were developed with 13 theoretical parameters to get reliable logKoc predictions. The leave-one-out cross validation (CV-LOO) indicated that the internal predictive power of the two models was satisfactory. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.

  9. Population growth and development of the psocid Liposcelis brunnea (Psocoptera: Liposcelididae) at constant temperatures and relative humidities.

    PubMed

    Opit, G P; Throne, J E

    2009-06-01

    We studied the effects of temperature and relative humidity on population growth and development of the psocid Liposcelis brunnea Motschulsky. L. brunnea did not survive at 43% RH, but populations increased from 22.5 to 32.5 degrees C and 55-75% RH. Interestingly, we found population growth was higher at 63% RH than at 75% RH, and the greatest population growth was recorded at 32.5 degrees C and 63% RH. At 35 degrees C, L. brunnea nymphal survivorship was 33%, and populations declined or barely grew. L. brunnea males have two to four nymphal instars, and the percentages of males with two, three, and four instars were 13, 82, and 5%, respectively. Female L. brunnea have three to five instars, and the percentages of females with three, four, and five instars were 18, 78, and 4%, respectively. The life cycle was shorter for males than females. We developed temperature-dependent development equations for male and female eggs, individual nymphal, combined nymphal, and combined immature stages and nymphal survivorship. The ability of L. brunnea to multiply rather rapidly at 55% RH may allow it to thrive under conditions of low relative humidity where other Liposcelis species may not. These data give us a better understanding of L. brunnea population dynamics and can be used to help develop effective management strategies for this psocid.

  10. Einstein-Podolsky-Rosen steering and coherence in the family of entangled three-qubit states

    NASA Astrophysics Data System (ADS)

    Kalaga, J. K.; Leoński, W.; Peřina, J.

    2018-04-01

    Considering the system of three interacting qubits, we analyze four families of states from the point of view of bipartite correlations appearing in two-qubit subsystems of a three-qubit model, such as Einstein-Podolsky-Rosen steering, entanglement, and coherence. We reveal mutual relations among the steering parameter, concurrence, and three measures of coherence (degree of coherence, first-, and second-order correlation functions). Analyzing in parallel the steerable and unsteerable states, we derive analytical formulas giving the maximal and minimal values of coherence measures as concurrence varies.

  11. 14 CFR 1221.107 - Establishment of the NASA Administrator's, Deputy Administrator's, and Associate Deputy...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... × 4 feet; (2) The Administrator's Flag has four stars; (3) The Deputy Administrator's Flag has three stars; and (4) The Associate Deputy Administrator's Flag has two stars. (b) Flags representing these...

  12. 14 CFR § 1221.107 - Establishment of the NASA Administrator's, Deputy Administrator's, and Associate Deputy...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... × 4 feet; (2) The Administrator's Flag has four stars; (3) The Deputy Administrator's Flag has three stars; and (4) The Associate Deputy Administrator's Flag has two stars. (b) Flags representing these...

  13. 14 CFR 1221.107 - Establishment of the NASA Administrator's, Deputy Administrator's, and Associate Deputy...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... × 4 feet; (2) The Administrator's Flag has four stars; (3) The Deputy Administrator's Flag has three stars; and (4) The Associate Deputy Administrator's Flag has two stars. (b) Flags representing these...

  14. 14 CFR 1221.107 - Establishment of the NASA Administrator's, Deputy Administrator's, and Associate Deputy...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... × 4 feet; (2) The Administrator's Flag has four stars; (3) The Deputy Administrator's Flag has three stars; and (4) The Associate Deputy Administrator's Flag has two stars. (b) Flags representing these...

  15. 14 CFR 1221.107 - Establishment of the NASA Administrator's, Deputy Administrator's, and Associate Deputy...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... × 4 feet; (2) The Administrator's Flag has four stars; (3) The Deputy Administrator's Flag has three stars; and (4) The Associate Deputy Administrator's Flag has two stars. (b) Flags representing these...

  16. Immunological evaluation of four arc welders exposed to fumes from ignited polyurethane (isocyanate) foam: antibodies and immune profiles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Broughton, A.; Thrasher, J.D.; Gard, Z.

    1988-01-01

    Four arc welders having a flu-like illness with multiple health complaints following an exposure to high concentrations of isocyanate fumes from ignited polyurethane foam underwent immunological tests as follows: ELISA antibody assays, activated lymphocyte profiles, and lymphocyte blastogenesis. ELISA procedures revealed the presence of antibodies to hexamethylene diisocyanate (HDI) and formaldehyde (F) conjugated to human serum albumin (HDI-SA and F-SA). The results from the activated lymphocyte profiles showed deviations from the norm as follows: three welders had elevated helper/suppressor (H/S) ratios; all four had elevated percentages of Tal positive cells; two had decreases in B cells; and one had lowmore » total white cell and lymphocyte counts. In contrast, the percentage and absolute numbers of ILS receptor cells were normal in the four subjects. T cell blastogenesis to PHA, Con A and PWM resulted in the following: T-cells from one subject responded normally; in another, a high response (212% of controls) to PHA occurred with normal mitogenesis to Con A and PWM. In the remaining two welders, the T cells responded abnormally low (50 to 75% of controls) to the three mitogens. In conclusion, the existence of IgG antibodies to HDI-SA and F-SA, the altered activated immune profiles, the elevated Tal cells, and the abnormal blastogenesis are interpreted as being linked with the episode of HDI and F exposure and the subsequent flu-like illness of the four welders.« less

  17. Chemotherapy for management of localised high-grade gastric B-cell lymphoma: how much is necessary?

    PubMed

    Raderer, M; Chott, A; Drach, J; Montalban, C; Dragosics, B; Jäger, U; Püspök, A; Osterreicher, C; Zielinski, C C

    2002-07-01

    Recent data suggest that chemotherapy with the cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP) regimen is a highly effective treatment for localised primary gastric lymphoma of diffuse large B-cell histology (DLBCL). We have reported that the large majority of patients achieve complete remission (CR) following three cycles of treatment, and now provide an updated series with special emphasis on patients receiving only short-term chemotherapy. All patients with a histologically verified diagnosis of gastric DLBCL in stages EI and EII(1) undergoing chemotherapy with the CHOP regimen were evaluated. Data analysed included clinical stage, histology [presence of an additional mucosa-associated lymphoid tissue (MALT) component], evidence of Helicobacter pylori infection, H. pylori eradication, time to CR, survival and regular restaging (i.e. after three and six cycles, respectively). A total of 37 patients with DLBCL of the stomach with localised disease were identified, five of whom also had a MALT component. Twenty-two patients presented with stage EI and 15 with stage EII(1) disease. All patients were given chemotherapy as sole management of their lymphoma; 36 patients received CHOP, while one patient was given CHOP along with rituximab. Thirty-two (86%) achieved a CR after a maximum of three cycles, while only four patients had to be given six cycles for CR. In total, nine of 37 patients (24%) discontinued therapy earlier than scheduled: one patient received one cycle, two received two, six received three and one patient received four cycles. Two of these patients stopped treatment due to toxicity, i.e. protracted thrombocytopenia or chemotherapy extravasation. One additional patient died after one cycle of treatment; autopsy disclosed no signs of remaining lymphoma. Three patients have died after a median follow-up of 39 months (including the one patient who discontinued therapy after one cycle of treatment), while the remaining 34 patients are alive without evidence of disease. Twenty-four out of 37 patients (65%) had also undergone H. pylori eradication (including six of nine patients receiving only short-term treatment). DLBCL of the stomach appears to be a highly chemosensitive disease. Our data question the need for full-term CHOP treatment in patients achieving CR upon first follow-up. However, recent data suggest that additional H. pylori eradication might have contributed to the excellent results achieved in our series.

  18. Quasi-four-body treatment of charge transfer in the collision of protons with atomic helium: I. Thomas related mechanisms

    NASA Astrophysics Data System (ADS)

    Safarzade, Zohre; Fathi, Reza; Shojaei Akbarabadi, Farideh; Bolorizadeh, Mohammad A.

    2018-04-01

    The scattering of a completely bare ion by atoms larger than hydrogen is at least a four-body interaction, and the charge transfer channel involves a two-step process. Amongst the two-step interactions of the high-velocity single charge transfer in an anion-atom collision, there is one whose amplitude demonstrates a peak in the angular distribution of the cross sections. This peak, the so-called Thomas peak, was predicted by Thomas in a two-step interaction, classically, which could also be described through three-body quantum mechanical models. This work discusses a four-body quantum treatment of the charge transfer in ion-atom collisions, where two-step interactions illustrating a Thomas peak are emphasized. In addition, the Pauli exclusion principle is taken into account for the initial and final states as well as the operators. It will be demonstrated that there is a momentum condition for each two-step interaction to occur in a single charge transfer channel, where new classical interactions lead to the Thomas mechanism.

  19. Three-Year-Old Photographers: Educational and Parental Mediation as a Basis for Visual Literacy via Digital Photography in Early Childhood

    ERIC Educational Resources Information Center

    Friedman, Arielle

    2016-01-01

    The study examines two years of an educational program for children aged three to four, based on the use of digital cameras. It assesses the program's effects on the children and adults involved in the project, and explores how they help the youngsters acquire visual literacy. Operating under the assumption that formal curricula usually…

  20. A Case Study of 2-4 Transfer in New Jersey: Implementation of a Transfer Law at Three Community Colleges

    ERIC Educational Resources Information Center

    McCormick, Mark Allen

    2017-01-01

    The purpose of this study was to examine ways in which the 2007 New Jersey transfer law mandating "seamless transfer" between public two- and four-year colleges has been implemented at three community colleges and the state's flagship research university and the forces that have contributed to and limited the extent to which the law has…

  1. Versatile tunable current-mode universal biquadratic filter using MO-DVCCs and MOSFET-based electronic resistors.

    PubMed

    Chen, Hua-Pin

    2014-01-01

    This paper presents a versatile tunable current-mode universal biquadratic filter with four-input and three-output employing only two multioutput differential voltage current conveyors (MO-DVCCs), two grounded capacitors, and a well-known method for replacement of three grounded resistors by MOSFET-based electronic resistors. The proposed configuration exhibits high-output impedance which is important for easy cascading in the current-mode operations. The proposed circuit can be used as either a two-input three-output circuit or a three-input single-output circuit. In the operation of two-input three-output circuit, the bandpass, highpass, and bandreject filtering responses can be realized simultaneously while the allpass filtering response can be easily obtained by connecting appropriated output current directly without using additional stages. In the operation of three-input single-output circuit, all five generic filtering functions can be easily realized by selecting different three-input current signals. The filter permits orthogonal controllability of the quality factor and resonance angular frequency, and no inverting-type input current signals are imposed. All the passive and active sensitivities are low. Postlayout simulations were carried out to verify the functionality of the design.

  2. Versatile Tunable Current-Mode Universal Biquadratic Filter Using MO-DVCCs and MOSFET-Based Electronic Resistors

    PubMed Central

    2014-01-01

    This paper presents a versatile tunable current-mode universal biquadratic filter with four-input and three-output employing only two multioutput differential voltage current conveyors (MO-DVCCs), two grounded capacitors, and a well-known method for replacement of three grounded resistors by MOSFET-based electronic resistors. The proposed configuration exhibits high-output impedance which is important for easy cascading in the current-mode operations. The proposed circuit can be used as either a two-input three-output circuit or a three-input single-output circuit. In the operation of two-input three-output circuit, the bandpass, highpass, and bandreject filtering responses can be realized simultaneously while the allpass filtering response can be easily obtained by connecting appropriated output current directly without using additional stages. In the operation of three-input single-output circuit, all five generic filtering functions can be easily realized by selecting different three-input current signals. The filter permits orthogonal controllability of the quality factor and resonance angular frequency, and no inverting-type input current signals are imposed. All the passive and active sensitivities are low. Postlayout simulations were carried out to verify the functionality of the design. PMID:24982963

  3. [H{sub 2}en]{sub 2}{l_brace}La{sub 2}M(SO{sub 4}){sub 6}(H{sub 2}O){sub 2}{r_brace} (M=Co, Ni): First organically templated 3d-4f mixed metal sulfates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yuan Yanping; Wang Ruiyao; Kong Deyuan

    2005-06-15

    The first organically templated 3d-4f mixed metal sulfates, [H{sub 2}en]{sub 2}{l_brace}La{sub 2}M(SO{sub 4}){sub 6}(H{sub 2}O){sub 2}{r_brace} (M=Co 1, Ni 2) have been synthesized and structurally determined from non-merohedrally twinned crystals. The two compounds are isostructural and their structures feature a three-dimensional anionic network formed by the lanthanum(III) and nickel(II) ions bridged by sulfate anions. The La(III) ions in both compounds are 10-coordinated by four sulfate anions in bidentate chelating fashion, and two sulfate anions in a unidentate fashion. The transition metal(II) ion is octahedrally coordinated by six oxygens from four sulfate anions and two aqua ligands. The doubly protonated enthylenediaminemore » cations are located at the tunnels formed by 8-membered rings (four La and four sulfate anions)« less

  4. Exp(1076) Shades of Black: Aspects of Black Hole Microstates

    NASA Astrophysics Data System (ADS)

    Vasilakis, Orestis

    In this thesis we examine smooth supergravity solutions known as "microstate geometries". These solutions have neither a horizon, nor a singularity, yet they have the same asymptotic structure and conserved charges as black holes. Specifically we study supersymmetric and extremal non-supersymmetric solutions. The goal of this program is to construct enough microstates to account for the correct scaling behavior of the black hole entropy with respect to the charges within the supergravity approximation. For supersymmetric systems that are ⅛-BPS, microstate geometries account so far only for Q5/4 of the total entropy S ˜ Q3/2, while for non-supersymmetric systems the known microstate geometries are sporadic. For the supersymmetric case we construct solutions with three and four charges. Five-dimensional systems with three and four charges are ⅛-BPS. Thus they admit macroscopic horizons making the supergravity approximation valid. For the three-charge case we present some steps towards the construction of the superstratum, a microstate geometry depending on arbitrary functions of two variables, which is expected to provide the necessary entropy for this class of solutions. Specifically we construct multiple concentric solutions with three electric and two dipole magnetic charges which depend on arbitrary functions of two variables and examine their properties. These solutions have no KKM charge and thus are singular. For the four-charge case we construct microstate geometries by extending results available in the literature for three charges. We find smooth solutions in terms of bubbled geometries with ambipolar Gibbons-Hawking base space and by constructing the relevant supertubes. In the non-supersymmetric case we work with a three-charge system of extremal black holes known as almost-BPS, which provides a controlled way of breaking sypersymmetry. By using supertubes we construct the first systematic example of a family of almost-BPS microstate geometries and examine the moduli space of solutions. Furthermore by using brane probe analysis we show that, despite the breaking of supersymmetry, almost-BPS solutions receive no quantum corrections and thus must be subject to some kind of non-renormalization theorem.

  5. A two-dimensional Zn coordination polymer with a three-dimensional supra-molecular architecture.

    PubMed

    Liu, Fuhong; Ding, Yan; Li, Qiuyu; Zhang, Liping

    2017-10-01

    The title compound, poly[bis-{μ 2 -4,4'-bis-[(1,2,4-triazol-1-yl)meth-yl]biphenyl-κ 2 N 4 : N 4' }bis-(nitrato-κ O )zinc(II)], [Zn(NO 3 ) 2 (C 18 H 16 N 6 ) 2 ] n , is a two-dimensional zinc coordination polymer constructed from 4,4'-bis-[(1 H -1,2,4-triazol-1-yl)meth-yl]-1,1'-biphenyl units. It was synthesized and characterized by elemental analysis and single-crystal X-ray diffraction. The Zn II cation is located on an inversion centre and is coordinated by two O atoms from two symmetry-related nitrate groups and four N atoms from four symmetry-related 4,4'-bis-[(1 H -1,2,4-triazol-1-yl)meth-yl]-1,1'-biphenyl ligands, forming a distorted octa-hedral {ZnN 4 O 2 } coordination geometry. The linear 4,4'-bis-[(1 H -1,2,4-triazol-1-yl)meth-yl]-1,1'-biphenyl ligand links two Zn II cations, generating two-dimensional layers parallel to the crystallographic (132) plane. The parallel layers are connected by C-H⋯O, C-H⋯N, C-H⋯π and π-π stacking inter-actions, resulting in a three-dimensional supra-molecular architecture.

  6. A systematic review of patient-reported outcome measures in clinical vestibular research

    PubMed Central

    Fong, Eric; Li, Carol; Aslakson, Rebecca; Agrawal, Yuri

    2014-01-01

    Objective To identify the most commonly-used patient-reported outcome (PRO) measures in clinical vestibular research, and assess their test characteristics and applicability to study age-related vestibular loss (ARVL) in clinical trials. Data Sources We performed a systematic review of the PubMed, CINAHL, and PsycINFO databases from 1950 to August 13, 2013. Study Selection PRO measures were defined as outcomes that capture the subjective experience of the patient, such as symptoms, functional status, health perceptions, and quality of life. Two independent reviewers selected studies that used PRO measures in clinical vestibular research. Disparities were resolved with consensus between the reviewers. Of 2260 articles initially found on literature search, 255 full-text articles were retrieved for assessment. One-hundred and four studies met inclusion criteria for data collection. Data Extraction PRO measures were identified by two independent reviewers. The four most commonly used PROs were evaluated for their applicability to the condition of ARVL. Specifically, for these four PROs, data were collected pertaining to instrument test-retest reliability, item domains, and target population of the instrument. Data Synthesis A total of 50 PRO instruments were identified. The four most frequently utilized PROs were the Dizziness Handicap Inventory (DHI), the Activities-specific Balance Confidence (ABC) scale, the Vertigo Symptom Scale (VSS), and the Visual Analogue Scale (VAS). Of these four PROs, three were validated for use in patients with vestibular disease, and one was validated in community-dwelling older individuals with balance impairments. Items across the four PROs were categorized into three domains based on the International Classification of Functioning, Disability and Health: Activity, Participation, and Body Functions and Structures. Conclusions None of the most commonly-used PRO instruments were validated for use in community-dwelling older adults specifically with ARVL. Nevertheless, the three common domains of items identified across these four PRO instruments may be generalizable to older adults and provide a basis for developing a PRO instrument designed to evaluate the effectiveness of interventions targeted to ARVL. PMID:25305629

  7. Atherosclerosis across 4000 years of human history: the Horus study of four ancient populations.

    PubMed

    Thompson, Randall C; Allam, Adel H; Lombardi, Guido P; Wann, L Samuel; Sutherland, M Linda; Sutherland, James D; Soliman, Muhammad Al-Tohamy; Frohlich, Bruno; Mininberg, David T; Monge, Janet M; Vallodolid, Clide M; Cox, Samantha L; Abd el-Maksoud, Gomaa; Badr, Ibrahim; Miyamoto, Michael I; el-Halim Nur el-Din, Abd; Narula, Jagat; Finch, Caleb E; Thomas, Gregory S

    2013-04-06

    Atherosclerosis is thought to be a disease of modern human beings and related to contemporary lifestyles. However, its prevalence before the modern era is unknown. We aimed to evaluate preindustrial populations for atherosclerosis. We obtained whole body CT scans of 137 mummies from four different geographical regions or populations spanning more than 4000 years. Individuals from ancient Egypt, ancient Peru, the Ancestral Puebloans of southwest America, and the Unangan of the Aleutian Islands were imaged. Atherosclerosis was regarded as definite if a calcified plaque was seen in the wall of an artery and probable if calcifications were seen along the expected course of an artery. Probable or definite atherosclerosis was noted in 47 (34%) of 137 mummies and in all four geographical populations: 29 (38%) of 76 ancient Egyptians, 13 (25%) of 51 ancient Peruvians, two (40%) of five Ancestral Puebloans, and three (60%) of five Unangan hunter gatherers (p=NS). Atherosclerosis was present in the aorta in 28 (20%) mummies, iliac or femoral arteries in 25 (18%), popliteal or tibial arteries in 25 (18%), carotid arteries in 17 (12%), and coronary arteries in six (4%). Of the five vascular beds examined, atherosclerosis was present in one to two beds in 34 (25%) mummies, in three to four beds in 11 (8%), and in all five vascular beds in two (1%). Age at time of death was positively correlated with atherosclerosis (mean age at death was 43 [SD 10] years for mummies with atherosclerosis vs 32 [15] years for those without; p<0·0001) and with the number of arterial beds involved (mean age was 32 [SD 15] years for mummies with no atherosclerosis, 42 [10] years for those with atherosclerosis in one or two beds, and 44 [8] years for those with atherosclerosis in three to five beds; p<0·0001). Atherosclerosis was common in four preindustrial populations including preagricultural hunter-gatherers. Although commonly assumed to be a modern disease, the presence of atherosclerosis in premodern human beings raises the possibility of a more basic predisposition to the disease. National Endowment for the Humanities, Paleocardiology Foundation, The National Bank of Egypt, Siemens, and St Luke's Hospital Foundation of Kansas City. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. Do the stars align? Distribution of high-quality ratings of healthcare sectors across US markets.

    PubMed

    Figueroa, Jose; Feyman, Yevgeniy; Blumenthal, Daniel; Jha, Ashish

    2018-04-01

    The US government created five-star rating systems to evaluate hospital, nursing homes, home health agency and dialysis centre quality. The degree to which quality is a property of organisations versus geographical markets is unclear. To determine whether high-quality healthcare service sectors are clustered within US healthcare markets. Using data from the Centers for Medicare and Medicaid Services' Hospital, Dialysis, Nursing Home and Home Health Compare databases, we calculated the mean star ratings of four healthcare sectors in 304 US hospital referral regions (HRRs). For each sector, we ranked HRRs into terciles by mean star rating. Within each HRR, we assessed concordance of tercile rank across sectors using a multirater kappa. Using t-tests, we compared characteristics of HRRs with three to four top-ranked sectors, one to two top-ranked sectors and zero top-ranked sectors. Six HRRs (2.0% of HRRs) had four top-ranked healthcare sectors, 38 (12.5%) had three top-ranked health sectors, 71 (23.4%) had two top-ranked sectors, 111 (36.5%) had one top-ranked sector and 78 (25.7%) HRRs had no top-ranked sectors. A multirater kappa across all sectors showed poor to slight agreement (K=0.055). Compared with HRRs with zero top-ranked sectors, those with three to four top-ranked sectors had higher median incomes, fewer black residents, lower mortality rates and were less impoverished. Results were similar for HRRs with one to two top-ranked sectors. Few US healthcare markets exhibit high-quality performance across four distinct healthcare service sectors, suggesting that high-quality care in one sector may not be dependent on or improve care quality in other sectors. Policies that promote accountability for quality across sectors (eg, bundled payments and shared quality metrics) may be needed to systematically improve quality across sectors. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  9. A plastid phylogeny and character evolution of the Old World fern genus Pyrrosia (Polypodiaceae) with the description of a new genus: Hovenkampia (Polypodiaceae).

    PubMed

    Zhou, Xin-Mao; Zhang, Liang; Chen, Cheng-Wei; Li, Chun-Xiang; Huang, Yao-Moan; Chen, De-Kui; Lu, Ngan Thi; Cicuzza, Daniele; Knapp, Ralf; Luong, Thien Tam; Nitta, Joel H; Gao, Xin-Fen; Zhang, Li-Bing

    2017-09-01

    The Old World fern genus Pyrrosia (Polypodiaceae) offers a rare system in ferns to study morphological evolution because almost all species of this genus are well studied for their morphology, anatomy, and spore features, and various hypotheses have been proposed in terms of the phylogeny and evolution in this genus. However, the molecular phylogeny of the genus lags behind. The monophyly of the genus has been uncertain and a modern phylogenetic study of the genus based on molecular data has been lacking. In the present study, DNA sequences of five plastid markers of 220 accessions of Polypodiaceae representing two species of Drymoglossum, 14 species of Platycerium, 50 species of Pyrrosia, and the only species of Saxiglossum (subfamily Platycerioideae), and 12 species of other Polypodiaceae representing the remaining four subfamilies are used to infer a phylogeny of the genus. Major results and conclusions of this study include: (1) Pyrrosia as currently circumscribed is paraphyletic in relation to Platycerium and can be divided into two genera: Pyrrosia s.s. and Hovenkampia (gen. nov.), with Hovenkampia and Platycerium forming a strongly supported clade sister to Pyrrosia s.s.; (2) Subfamily Platycerioideae should contain three genera only, Hovenkampia, Platycerium, and Pyrrosia s.s.; (3) Based on the molecular phylogeny, macromorphology, anatomical features, and spore morphology, four major clades in the genus are identified and three of the four are further resolved into four, four, and six subclades, respectively; (4) Three species, P. angustissima, P. foveolata, and P. mannii, not assigned to any groups by Hovenkamp (1986) because of their unusual morphology, each form monospecific clades; (5) Drymoglossum is not monophyletic and those species previously assigned to this genus are resolved in two different subclades; (6) Saxiglossum is resolved as the first lineage in the Niphopsis clade; and (7) The evolution of ten major morphological characters in the subfamily is inferred based on the phylogeny and various morphological synapomorphies for various clades and subclades are identified. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Group premiums in micro health insurance experiences from Tanzania.

    PubMed

    Kiwara, Angwara D

    2007-04-01

    The main objective was to assess how group premiums can help poor people in the informal economy prepay for health care services. A comparative approach was adopted to study four groups of informal economy operators (cobblers, welders, carpenters, small scale market retailers) focusing on a method of prepayment which could help them access health care services. Two groups with a total of 714 operators were organized to prepay for health care services through a group premium, while the other two groups with a total of 702 operators were not organized to prepay through this approach. They prepaid through individual premium, each operator paying from his or her sources. Data on the four groups which lived in the same city was collected through a questionnaire and focus group discussions. Data collected was focused on health problems, health seeking behaviour and payment for health care services. Training of all the groups on prepaid health care financing based on individual based premium payment and group based premium payment was done. Groups were then free to choose which method to use in prepaying for health care. Prepayment through the two methods was then observed over a period of three years. Trends of membership attrition and retention were documented for both approaches. Data collected showed that the four groups were similar in many respects. These similarities included levels of education, housing, and social services such as water supplies, health problems, family size and health seeking behaviour. At the end of a period of three years 76% of the members from the two groups who chose group premium payment were still members of the prepayment health scheme and were receiving health care. For the two groups which opted for individual premium payment only 15% of their members were still receiving health care services at the end of three years. Group premium is a useful tool in improving accessibility to health care services in the poorer segments of the population especially the informal economy operators

  11. Performance of Single-Stage Turbine of Mark 25 Torpedo Power Plant with Two Nozzles and Three Rotor-Blade Designs

    NASA Technical Reports Server (NTRS)

    Schum, Harold J.; Whitney, Warren J.

    1949-01-01

    A single-stage modification of the turbine from a Mark 25 torpedo power plant was investigated to determine the performance with two nozzles and three rotor-blade designs. The performance was evaluated in terms of brake, rotor, and blade efficiencies at pressure ratios of 8, 15 (design), and 20. The blade efficiencies with the two nozzles are compared with those obtained with four other nozzles previously investigated with the same three rotor-blade designs. Blade efficiency with the cast nozzle of rectangular cross section (J) was higher than that with the circular reamed nozzle (K) at all speeds and pressure ratios with a rotor having a 0.45-inch 17 degree-inlet-angle blades. The efficiencies for both these nozzles were generally low compared with those of the four other nozzles previously investigated in combination with this rotor. At pressure ratios of 15 and 20, the blade efficiencies with nozzle K and the two rotors with 0.40-inch blades having different inlet angles were higher than with the four other nozzles, but the efficiency with nozzle J was generally low. Increasing the blade inlet angle from 17 degrees to 20 degrees had little effect on turbine performance, whereas changing the blade length from 0.40 to 0.45 inch had a marked effect. Although a slight correlation of efficiency with nozzle size was noted for the rotor with 0.45-inch 17 degree-inlet-angle blades, no such effect was discernible ,for the two rotors with 0.40-inch blades.Losses in the supersonic air stream resulting from the complex flow path in the small air passages are probably a large percentage of the total losses, and apparently the effects of changing nozzle size and shape within the limits investigated are of secondary importance.

  12. Space Shuttle Projects

    NASA Image and Video Library

    2001-04-01

    The STS-105 crew patch symbolizes the exchange of the Expedition Two and Expedition Three crews aboard the International Space Station (ISS). The three gold stars near the ascending orbiter represent the U.S. commanded Expedition Three Crew journeying into space, while the two gold stars near the descending orbiter represent the Russian commanded Expedition Two crew on their return to Earth. The ascending and descending Orbiters form a circle that represents both the crew rotation and the continuous presence in space aboard the station. The plumes of each orbiter represent the flags of the U.S. and Russia, symbolizing the close cooperation between the two nations. The Astronaut office symbol, a star with three rays of light, depicts the unbroken link between Earth and the brightest star on the horizon, the ISS. The names of Discovery's crew of four astronauts are shown along the border of the patch while the names of the Expedition crews are shown on the chevron at the bottom of the patch.

  13. The structure of post-traumatic stress disorder symptoms in three female trauma samples: A comparison of interview and self-report measures

    PubMed Central

    Scher, Christine D.; McCreary, Donald R.; Asmundson, Gordon J.G.; Resick, Patricia A.

    2009-01-01

    Empirical research increasingly suggests that post-traumatic stress disorder (PTSD) is comprised of four factors: re-experiencing, avoidance, numbing, and hyperarousal. Nonetheless, there remains some inconsistency in the findings of factor analyses that form the bulk of this empirical literature. One source of such inconsistency may be assessment measure idiosyncrasies. To examine this issue, we conducted confirmatory factor analyses of interview and self-report data across three trauma samples. Analyses of the interview data indicated a good fit for a four-factor model across all samples; analyses of the self-report data indicated an adequate fit in two of three samples. Overall, findings suggest that measure idiosyncrasies may account for some of the inconsistency in previous factor analyses of PTSD symptoms. PMID:18206346

  14. Espresso Coffee for the Treatment of Somnolence in Parkinson’s Disease: Results of n-of-1 Trials

    PubMed Central

    Ferreira, Joaquim J.; Mestre, Tiago; Guedes, Leonor Correia; Coelho, Miguel; Rosa, Mário M.; Santos, Ana T.; Barra, Márcio; Sampaio, Cristina; Rascol, Olivier

    2016-01-01

    There is limited information available concerning the treatment of daytime somnolence associated with Parkinson’s disease (PD); the most frequently applied therapeutic strategies include decreasing the dose of dopamine agonists or adding potential wake-promoting agents. There is recent data from a placebo-controlled trial concluding on a non-significant trend in favor of caffeine. We aimed to evaluate the efficacy of espresso-coffee in the treatment of daytime somnolence in PD. To evaluate the efficacy of espresso-coffee in the treatment of daytime somnolence in PD, we have conducted multiple single-patient (n-of-1) clinical trials comparing regular espresso coffee to decaffeinated coffee in PD patients presenting moderate to severe daytime somnolence defined as an Epworth Sleepiness Scale score >9. Each single-patient (n-of-1) trial included a sequence of three crossovers (two treatment periods separated by two days of washout). Four patients were included in the studies and three completed the three pairs of treatment periods. In two of the four patients, espresso coffee was considered beneficial. This study concludes that multiple single patient trials are feasible in PD and suggests that espresso-coffee may have a beneficial effect on daytime somnolence in some patients. These results cannot be generalized beyond the patients included in these trials. PMID:27014181

  15. Light microscopic study of four plagiorchiid trematodes infecting marine fish in the south-eastern Mediterranean Sea, Alexandria City, with descriptions of two new species.

    PubMed

    Abdel-Gaber, Rewaida; Abdel-Ghaffar, Fathy; Mehlhorn, Heinz; Al Quraishy, Saleh; Morsy, Kareem; Maher, Sherein

    2018-05-01

    During the present investigation, a total of 220 fish specimens belonging to three different species, namely, little tunny Euthynnus alletteratus, African snook Lates niloticus, and striped red mullet Mullus surmuletus, were collected from January-November 2016 from the coasts off Abu Qir landing site, Alexandria City, south-eastern Mediterranean Sea, Egypt. The collected fish samples were dissected and examined for the presence of helminth parasites. Twenty-three out of 220 (10.45%) fish specimens were found to be naturally infected with four species of trematode parasites belonging to three different families of the order Plagiorchiida. The recovered parasite species were collected and identified by applying light microscopic examinations. The present study recorded two new parasite species, namely, Stephanostomum alletterani sp. nov. and Bathycreadium mulli sp. nov., belonging to the families Acanthocolpidae and Opecoelidae and infecting E. alletteratus and M. surmuletus, respectively and re-descriptions of the two remaining species, namely, Acanthostomum spiniceps and Aponurus mulli of the families Acanthostomatidae and Opecoelidae, respectively, to clarify the measurements of some body parts. Morphological and morphometric characterizations revealed some differences between the present species and other related species detected previously. Future studies are recommended to include advanced molecular characteristics for these species.

  16. On the biosorption, by brown seaweed, Lobophora variegata, of Ni(II) from aqueous solutions: equilibrium and thermodynamic studies.

    PubMed

    Basha, Shaik; Jaiswar, Santlal; Jha, Bhavanath

    2010-09-01

    The biosorption equilibrium isotherms of Ni(II) onto marine brown algae Lobophora variegata, which was chemically-modified by CaCl(2) were studied and modeled. To predict the biosorption isotherms and to determine the characteristic parameters for process design, twenty-three one-, two-, three-, four- and five-parameter isotherm models were applied to experimental data. The interaction among biosorbed molecules is attractive and biosorption is carried out on energetically different sites and is an endothermic process. The five-parameter Fritz-Schluender model gives the most accurate fit with high regression coefficient, R (2) (0.9911-0.9975) and F-ratio (118.03-179.96), and low standard error, SE (0.0902-0.0.1556) and the residual or sum of square error, SSE (0.0012-0.1789) values to all experimental data in comparison to other models. The biosorption isotherm models fitted the experimental data in the order: Fritz-Schluender (five-parameter) > Freundlich (two-parameter) > Langmuir (two-parameter) > Khan (three-parameter) > Fritz-Schluender (four-parameter). The thermodynamic parameters such as DeltaG (0), DeltaH (0) and DeltaS (0) have been determined, which indicates the sorption of Ni(II) onto L. variegata was spontaneous and endothermic in nature.

  17. How Many Samples and How Many Culture Media To Diagnose a Prosthetic Joint Infection: a Clinical and Microbiological Prospective Multicenter Study

    PubMed Central

    Léger, Julie; Tandé, Didier; Plouzeau, Chloé; Valentin, Anne Sophie; Jolivet-Gougeon, Anne; Lemarié, Carole; Kempf, Marie; Héry-Arnaud, Geneviève; Bret, Laurent; Juvin, Marie Emmanuelle; Giraudeau, Bruno; Burucoa, Christophe

    2015-01-01

    Although numerous perioperative samples and culture media are required to diagnose prosthetic joint infection (PJI), their exact number and types have not yet been definitely determined with a high level of proof. We conducted a prospective multicenter study to determine the minimal number of samples and culture media required for accurate diagnosis of PJI. Over a 2-year period, consecutive patients with clinical signs suggesting PJI were included, with five perioperative samples per patient. The bacteriological and PJI diagnosis criteria were assessed using a random selection of two, three, or four samples and compared with those obtained using the recommended five samples (references guidelines). The results obtained with two or three culture media were then compared with those obtained with five culture media for both criteria. The times-to-positivity of the different culture media were calculated. PJI was confirmed in 215/264 suspected cases, with a bacteriological criterion in 192 (89%). The PJI was monomicrobial (85%) or polymicrobial (15%). Percentages of agreement of 98.1% and 99.7%, respectively, for the bacteriological criterion and confirmed PJI diagnosis were obtained when four perioperative samples were considered. The highest percentages of agreement were obtained with the association of three culture media, a blood culture bottle, a chocolate agar plate, and Schaedler broth, incubated for 5, 7, and 14 days, respectively. This new procedure leads to significant cost saving. Our prospective multicenter study showed that four samples seeded on three culture media are sufficient for diagnosing PJI. PMID:26637380

  18. How Many Samples and How Many Culture Media To Diagnose a Prosthetic Joint Infection: a Clinical and Microbiological Prospective Multicenter Study.

    PubMed

    Bémer, Pascale; Léger, Julie; Tandé, Didier; Plouzeau, Chloé; Valentin, Anne Sophie; Jolivet-Gougeon, Anne; Lemarié, Carole; Kempf, Marie; Héry-Arnaud, Geneviève; Bret, Laurent; Juvin, Marie Emmanuelle; Giraudeau, Bruno; Corvec, Stéphane; Burucoa, Christophe

    2016-02-01

    Although numerous perioperative samples and culture media are required to diagnose prosthetic joint infection (PJI), their exact number and types have not yet been definitely determined with a high level of proof. We conducted a prospective multicenter study to determine the minimal number of samples and culture media required for accurate diagnosis of PJI. Over a 2-year period, consecutive patients with clinical signs suggesting PJI were included, with five perioperative samples per patient. The bacteriological and PJI diagnosis criteria were assessed using a random selection of two, three, or four samples and compared with those obtained using the recommended five samples (references guidelines). The results obtained with two or three culture media were then compared with those obtained with five culture media for both criteria. The times-to-positivity of the different culture media were calculated. PJI was confirmed in 215/264 suspected cases, with a bacteriological criterion in 192 (89%). The PJI was monomicrobial (85%) or polymicrobial (15%). Percentages of agreement of 98.1% and 99.7%, respectively, for the bacteriological criterion and confirmed PJI diagnosis were obtained when four perioperative samples were considered. The highest percentages of agreement were obtained with the association of three culture media, a blood culture bottle, a chocolate agar plate, and Schaedler broth, incubated for 5, 7, and 14 days, respectively. This new procedure leads to significant cost saving. Our prospective multicenter study showed that four samples seeded on three culture media are sufficient for diagnosing PJI. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  19. Molecular and serological survey on taeniasis and cysticercosis in Kanchanaburi Province, Thailand.

    PubMed

    Anantaphruti, Malinee T; Okamoto, Munehiro; Yoonuan, Tippayarat; Saguankiat, Surapol; Kusolsuk, Teera; Sato, Megumi; Sato, Marcello O; Sako, Yasuhito; Waikagul, Jitra; Ito, Akira

    2010-09-01

    A community-based field survey on taeniasis and cysticercosis was performed in two villages in Thong Pha Phum District, Kanchanaburi Province, central Thailand, where 3 Taenia species, T. solium, T. saginata and T. asiatica, are sympatrically occurring. Four (0.6%) out of 667 stool samples were egg-positive for Taenia sp. by Kato-Katz technique. Three out of those four persons and other three persons who were Taenia egg-negative but having a recent (<1 year) history of discharging worms in stool were treated with niclosamide. One Taenia egg-positive woman was not treated because of severe ascites. After treatment, three persons expelled long strobilae with scolices and two persons expelled strobilae without scolex. One Taenia egg-positive person did not expel any worms post-treatment. Among 5 persons, four expelled a single worm, whereas one expelled multiple worms, may be 6 worms but not confirmed by detection of scolices. One scolex was armed with hooklets, whereas 2 others did not. Multiplex PCR of 10 expelled proglottids (including 6 estimated worms from one patient) revealed that one sample was T. solium, one T. saginata, and 8 T. asiatica. A total of 159 residents agreed to receive a serological test for cysticercosis. By ELISA using partially purified glycoprotein antigen, 9 cases, 5 and 4 from villages A and B respectively, were found to be sero-positive. The five and an additional sample on the border line from village A were evaluated using confirmative immunoblot using recombinant chimeric antigen. Among the six samples, four including the border line sample were confirmed to be cysticercosis by immunoblotting. One of the 4 persons had neurological symptoms with nodular lesions in the brain by computed tomography. These 4 confirmed or suspected cysticercosis cases were free of T. solium worms, but two of them including confirmed NCC case had a past (>1 year) history of expelling proglottids in the stool.

  20. Attachment typologies and posttraumatic stress disorder (PTSD), depression and anxiety: a latent profile analysis approach

    PubMed Central

    Armour, Cherie; Elklit, Ask; Shevlin, Mark

    2011-01-01

    Background Bartholomew (1990) proposed a four category adult attachment model based on Bowlby's (1973) proposal that attachment is underpinned by an individual's view of the self and others. Previous cluster analytic techniques have identified four and two attachment styles based on the Revised Adult Attachment Scale (RAAS). In addition, attachment styles have been proposed to meditate the association between stressful life events and subsequent psychiatric status. Objective The current study aimed to empirically test the attachment typology proposed by Collins and Read (1990). Specifically, LPA was used to determine if the proposed four styles can be derived from scores on the dimensions of closeness/dependency and anxiety. In addition, we aimed to test if the resultant attachment styles predicted the severity of psychopathology in response to a whiplash trauma. Method A large sample of Danish trauma victims (N=1577) participated. A Latent Profile Analysis was conducted, using Mplus 5.1, on scores from the RAAS scale to ascertain if there were underlying homogeneous attachment classes/subgroups. Class membership was used in a series of one-way ANOVA tests to determine if classes were significantly different in terms of mean scores on measures of psychopathology. Results The three class solution was considered optimal. Class one was termed Fearful (18.6%), Class two Preoccupied (34.5%), and Class three Secure (46.9%). The secure class evidenced significantly lower mean scores on PTSD, depression, and anxiety measures compared to other classes, whereas the fearful class evidenced significantly higher mean scores compared to other classes. Conclusions The results demonstrated evidence of three discrete classes of attachment styles, which were labelled secure, preoccupied, and fearful. This is in contrast to previous cluster analytic techniques which have identified four and two attachment styles based on the RAAS.In addition, Securely attached individuals display lower levels of psychopathology post whiplash trauma. PMID:22893805

  1. Influence of gel/LED-laser application on cervical microleakage of two barrier materials used for endodontically treated teeth whitening

    NASA Astrophysics Data System (ADS)

    Marchesan, Melissa Andréia; Barros, Felipe; Porto, Saulo; Zaitter, Suellen; Brugnera, Aldo, Jr.; Sousa-Neto, Manoel D.

    2007-02-01

    This study evaluated ex vivo the influence of the number of gel/LED-laser applications/activations on cervical microleakage of two different barrier materials used for protection during whitening of endodontically treated teeth. Eighty-four canines were instrumented and obturated with epoxy resin sealer. The seal was removed 2 mm beyond the cemento-enamel junction for barrier placement and the teeth were divided into two groups of 40 teeth each: G1, zinc phosphate cement; G2, glass ionomer cement. The two groups were subdivided into 4 subgroups (n=10 each): I) no gel or LED-laser application; II) one gel application and two LED-laser activations; III) two gel applications and four LED-laser activations; IV) three gel applications and six LED-laser activations. The teeth were immersed in India ink for 7 days, decalcified and cleared. Cervical microleakage was quantified with a measurement microscope. Statistical analysis showed that zinc phosphate caused significantly lower microleakage than glass ionomer cement (presented microleakage in all subgroups). However, after two (p<0.01) and three (p<0.001) applications of gel, there was statistially significant microleakage in zinc phosphate barriers. Based on the present results, it can be concluded that cervical barriers with zinc phosphate cement show less cervical microleakage and that two or more applications/activations of gel/LED-laser significantly increase microleakage.

  2. Study of coherence effects in a four-level Ξ‑Λ type system

    NASA Astrophysics Data System (ADS)

    Yadav, Kavita; Wasan, Ajay

    2018-05-01

    We theoretically study the two- and three-photon coherence in a Ξ‑Λ type four-level system for stationary as well moving atoms at the room temperature using density matrix formalism. We discuss the role of dressed states to elucidate the electromagnetically induced transparency and electromagnetically induced absorption phenomena. The presence of the third field induces absorption at the line centre. A negative dispersion slope owing to the enhanced absorption results in super-luminal light propagation and the group index variation with the coupling field is switched from sub- to super-luminal. Group index with probe detuning shows super-luminal light propagation behaviour at the dressed state positions. The three optical fields trigger four-wave mixing as a result of the third order nonlinearity. The transient evolution is also discussed for optimum strengths of the coupling and drive fields to realize the optical switching in the system.

  3. Solid state instrumentation concepts for earth resource observation

    NASA Technical Reports Server (NTRS)

    Richard, H. L.

    1982-01-01

    Late in 1980, specifications were prepared for detail design definition of a six band solid state multispectral instrument having three visible (VIS), one near infrared (NIR), and two short wave infrared (SWIR) bands. This instrument concept, known as the Multispectral Linear Array (MLA), also offered increased spatial resolution, on board gain and offset correction, and additional operational modes which would allow for cross track and stereoscopic viewing as well as a multialtitude operational capability. A description is presented of a summary of some of the salient features of four different MLA design concepts, as developed by four American companies. The designs ranged from the use of multiple refractive telescopes utilizing three groups of focal plane detectors electronic correlation processing for achieving spatial registration, and incorporating palladium silicide (PdSi) SWIR detectors, to a four-mirror all-reflective telecentric system utilizing a beam splitter for spatial registration.

  4. Spatial carrier color digital speckle pattern interferometry for absolute three-dimensional deformation measurement

    NASA Astrophysics Data System (ADS)

    Gao, Xinya; Wang, Yonghong; Li, Junrui; Dan, Xizuo; Wu, Sijin; Yang, Lianxiang

    2017-06-01

    It is difficult to measure absolute three-dimensional deformation using traditional digital speckle pattern interferometry (DSPI) when the boundary condition of an object being tested is not exactly given. In practical applications, the boundary condition cannot always be specifically provided, limiting the use of DSPI in real-world applications. To tackle this problem, a DSPI system that is integrated by the spatial carrier method and a color camera has been established. Four phase maps are obtained simultaneously by spatial carrier color-digital speckle pattern interferometry using four speckle interferometers with different illumination directions. One out-of-plane and two in-plane absolute deformations can be acquired simultaneously without knowing the boundary conditions using the absolute deformation extraction algorithm based on four phase maps. Finally, the system is proved by experimental results through measurement of the deformation of a flat aluminum plate with a groove.

  5. Pesticides in soils and ground water in selected irrigated agricultural areas near Havre, Ronan, and Huntley, Montana

    USGS Publications Warehouse

    Clark, D.W.

    1990-01-01

    Three areas in Montana representing a range of agricultural practices and applied pesticides, were studied to document whether agricultural pesticides are being transported into the soil and shallow groundwater in irrigated areas. Analytical scans for triazine herbicides, organic-acid herbicides, and carbamate insecticides were performed on soil and shallow groundwater samples. The results indicate pesticide residue in both types of samples. The concentrations of pesticides in the groundwater were less than Federal health-advisory limits. At the Havre Agricultural Experiment Station, eight wells were installed at two sites. All four soil samples and two of four water samples collected after application of pesticides contained detectable concentrations of atrazine or dicamba. In an area where seed potatoes are grown near Ronan, eight wells were installed at two sites. Pesticides were not detected after initial application of pesticides and irrigation water. The site was resampled after irrigation water was reapplied, and aldicarb metabolities were detected in four of five soil samples and one of five water samples. At the Huntley Agricultural Experiment Station, five wells were installed in a no-tillage corn field where atrazine was applied in 1987. Soil and water samples were collected in June and July 1988; pesticides were not detected in any samples. Results indicate residue of two pesticides in soil samples and three soluble pesticides in groundwater samples. Therefore, irrigated agricultural areas in Montana might be susceptible to transport of soluble pesticides through permeable soil to the shallow groundwater system. (USGS)

  6. Implantable automatic scanning pacemaker for termination of supraventricular tachycardia.

    PubMed

    Spurrell, R A; Nathan, A W; Bexton, R S; Hellestrand, K J; Nappholz, T; Camm, A J

    1982-03-01

    Thirteen patients suffering from reentrant supraventricular tachycardia have undergone implantation of a scanning extrastimulus pacemaker. This pacemaker is fully implanted and automatic, and it requires no external control device to activate or control it. The pacemaker is activated when tachycardia occurs. After four cycles an extrastimulus is induced with a preset coupling time from a sensed intracardiac potential, and every four cycles thereafter a further extrastimulus occurs, but on each occasion there is a decrement in coupling cycle by 6 ms until 90 ms of the cardiac cycle has been scanned by extrastimuli. When necessary, two extrastimuli can be introduced with a fixed but preset coupling time between them. Every four beats two extrastimuli are induced but the coupling time between the spontaneous cardiac potential and the first stimulus is decreased by 6 ms until 90 ms of the cardiac cycle has been scanned. The coupling time between the two stimuli is fixed throughout the scan. When termination of tachycardia occurs the successful timing variables are retained in the pacemaker memory so that at the onset of the next episode of tachycardia these settings are used first. Pacemaker pulse width, sensitivity, tachycardia trigger rate, coupling intervals for both stimuli and the use of single or double extrastimuli are all programmable transcutaneously. Three patients required single, and seven patients double ventricular premature stimuli; three patients required double atrial premature stimuli for termination of tachycardia. Despite frequent attacks of tachycardia before implantation, only two patients had a sustained attack of tachycardia after pacemaker implantation.

  7. Pigeons' Discrimination of Michotte's Launching Effect

    PubMed Central

    Young, Michael E; Beckmann, Joshua S; Wasserman, Edward A

    2006-01-01

    We trained four pigeons to discriminate a Michotte launching animation from three other animations using a go/no-go task. The pigeons received food for pecking at one of the animations, but not for pecking at the others. The four animations featured two types of interactions among objects: causal (direct launching) and noncausal (delayed, distal, and distal & delayed). Two pigeons were reinforced for pecking at the causal interaction, but not at the noncausal interactions; two other pigeons were reinforced for pecking at the distal & delayed interaction, but not at the other interactions. Both discriminations proved difficult for the pigeons to master; later tests suggested that the pigeons often learned the discriminations by attending to subtle stimulus properties other than the intended ones. PMID:17002229

  8. Blinking fluorescence of single donor-acceptor pairs: important role of "dark'' states in resonance energy transfer via singlet levels.

    PubMed

    Osad'ko, I S; Shchukina, A L

    2012-06-01

    The influence of triplet levels on Förster resonance energy transfer via singlet levels in donor-acceptor (D-A) pairs is studied. Four types of D-A pair are considered: (i) two-level donor and two-level acceptor, (ii) three-level donor and two-level acceptor, (iii) two-level donor and three-level acceptor, and (iv) three-level donor and three-level acceptor. If singlet-triplet transitions in a three-level acceptor molecule are ineffective, the energy transfer efficiency E=I_{A}/(I_{A}+I_{D}), where I_{D} and I_{A} are the average intensities of donor and acceptor fluorescence, can be described by the simple theoretical equation E(F)=FT_{D}/(1+FT_{D}). Here F is the rate of energy transfer, and T_{D} is the donor fluorescence lifetime. In accordance with the last equation, 100% of the donor electronic energy can be transferred to an acceptor molecule at FT_{D}≫1. However, if singlet-triplet transitions in a three-level acceptor molecule are effective, the energy transfer efficiency is described by another theoretical equation, E(F)=F[over ¯](F)T_{D}/[1+F[over ¯](F)T_{D}]. Here F[over ¯](F) is a function of F depending on singlet-triplet transitions in both donor and acceptor molecules. Expressions for the functions F[over ¯](F) are derived. In this case the energy transfer efficiency will be far from 100% even at FT_{D}≫1. The character of the intensity fluctuations of donor and acceptor fluorescence indicates which of the two equations for E(F) should be used to find the value of the rate F. Therefore, random time instants of photon emission in both donor and acceptor fluorescence are calculated by the Monte Carlo method for all four types of D-A pair. Theoretical expressions for start-stop correlators (waiting time distributions) in donor and acceptor fluorescence are derived. The probabilities w_{N}^{D}(t) and w_{N}^{A}(t) of finding N photons of donor and acceptor fluorescence in the time interval t are calculated for various values of the energy transfer rate F and for all four types of D-A pair. Comparison of the calculated D and A fluorescence trajectories with those measured by Weiss and co-workers proves the important role of triplet levels in energy transfer via singlet levels.

  9. Saving teenage lives : the case for graduated driver licensing

    DOT National Transportation Integrated Search

    1998-11-01

    Two recent public opinion surveys point to widespread support for graduated driver licensing. A 1996 public opinion poll conducted by the American Automobile Association found that nearly three out of four respondents favor limiting the use of cars b...

  10. Distribution of Candida albicans genotypes among family members

    NASA Technical Reports Server (NTRS)

    Mehta, S. K.; Stevens, D. A.; Mishra, S. K.; Feroze, F.; Pierson, D. L.

    1999-01-01

    Thirty-three families (71 subjects) were screened for the presence of Candida albicans in mouthwash or stool specimens; 12 families (28 subjects) were culture-positive for this yeast. An enrichment procedure provided a twofold increase in the recovery of C. albicans from mouthwash specimens. Nine of the twelve culture-positive families had two positive members each, two families had three positive members each, and one family had four positive members. Genetic profiles were obtained by three methods: pulsed-field gel electrophoresis; restriction endonuclease analysis, and random amplification of polymorphic DNA analysis. DNA fingerprinting of C. albicans isolated from one body site three consecutive times revealed that each of the 12 families carried a distinct genotype. No two families shared the same strain, and two or more members of a family commonly shared the same strain. Intrafamily genotypic identity (i.e., each member within the family harbored the same strain) was demonstrated in six families. Genotypes of isolates from husband and wife differed from one another in five families. All three methods were satisfactory in determining genotypes; however, we concluded that restriction endonuclease analysis provided adequate resolving power.

  11. Theoretical design of twelve-band infrared metamaterial perfect absorber by combining the dipole, quadrupole, and octopole plasmon resonance modes of four different ring-strip resonators.

    PubMed

    Zhao, Lei; Liu, Han; He, Zhihong; Dong, Shikui

    2018-05-14

    Multiband metamaterial perfect absorbers (MPAs) have promising applications in many fields like microbolometers, infrared detection, biosensing, and thermal emitters. In general, the single resonator can only excite a fundamental mode and achieve single absorption band. The multiband MPA can be achieved by combining several different sized resonators together. However, it's still challenging to design the MPA with absorption bands of more than four and average absorptivity of more than 90% due to the interaction between differently sized resonators. In this paper, three absorption bands are successfully achieved with average absorptivity up to 98.5% only utilizing single one our designed ring-strip resonator, which can simultaneously excite a fundamental electric dipole mode, a higher-order electric quadrupole mode, and a higher-order electric octopole mode. As the biosensor, the sensing performance of the higher-order modes is higher than the fundamental modes. Then we try to increase the absorption bands by combining different sized ring-strip resonators together and make the average absorptivity above 90% by optimizing the geometry parameters. A six-band MPA is achieved by combining two different sized ring-strip resonators with average absorptivity up to 98.8%, which can excite two dipole modes, two quadrupole modes, and two octopole modes. A twelve-band MPA is achieved by combining four different sized ring-strip resonators with average absorptivity up to 93.7%, which can excite four dipole modes, four quadrupole modes, and four octopole modes.

  12. Multiband guided-mode resonance filter in bilayer asymmetric metallic gratings

    NASA Astrophysics Data System (ADS)

    Wang, Yanhui; Li, Xiangjun; Lang, Tingting; Jing, Xufeng; Hong, Zhi

    2018-07-01

    In this paper, a guided-mode resonances (GMRs) based multiband filter in bilayer asymmetric metallic gratings is presented. Four sharp dips are generated in the frequency range of 1.4-2.0 THz, which are induced by the split of two GMR modes (TE0 and TM0) due to the break of the structure's symmetry. This symmetry of the structure depends on the relative position between the upper layer and lower layer gratings. Therefore, by choosing proper lateral displacement, the split of TE0 or/and TM0 modes can be eliminated. Two-, three-, and four- GMRs based polarization insensitive or sensitive filters are demonstrated numerically.

  13. Changes in morphology of long bone marrow tissue of rats submitted to cryotherapy with liquid nitrogen.

    PubMed

    Costa, Fábio Wildson Gurgel; Pessoa, Rosana Maria Andrade; Nogueira, Carlos Bruno Pinheiro; Pereira, Karuza Maria Alves; Brito, Gerly Anne de Castro; Soares, Eduardo Costa Studart

    2012-02-01

    To study the main effects of local use of liquid nitrogen on bone marrow tissue in rats. The femoral diaphyses of 42 Wistar rats were exposed to three local and sequential applications of liquid nitrogen for one or two minutes, intercalated with periods of five minutes of passive thawing. The animals were sacrificed after one, two, four and 12 weeks and the specimens obtained were analyzed histomorphologically. In the second experimental week of one-minute protocol, histological degree of inflammation obtained a mean score of one (mild), ranging from 0 (absent or scarce) and two (moderate) (Kruskal-Wallis test p=0.01). In the second experimental week of two-minute protocol, degree of inflammation to the medullar tissue obtained an average score of two (Kruskal-Wallis test p=0.01). The degree of inflammation of the bone marrow tissue was higher in protocol of three applications of two minutes compared to protocol of three applications of one minute.

  14. Quantitative evaluation of rejuvenators to restore embrittlement temperatures in oxidized asphalt mixtures using acoustic emission

    NASA Astrophysics Data System (ADS)

    Sun, Zhe; Farace, Nicholas; Arnold, Jacob; Behnia, Behzad; Buttlar, William G.; Reis, Henrique

    2015-03-01

    Towards developing a method capable to assess the efficiency of rejuvenators to restore embrittlement temperatures of oxidized asphalt binders towards their original, i.e., unaged values, three gyratory compacted specimens were manufactured with mixtures oven-aged for 36 hours at 135 °C. In addition, one gyratory compacted specimen manufactured using a short-term oven-aged mixture for two hours at 155 °C was used for control to simulate aging during plant production. Each of these four gyratory compacted specimens was then cut into two cylindrical specimen 5 cm thick for a total of six 36-hour oven-aged specimens and two short term aging specimens. Two specimens aged for 36 hours and the two short-term specimens were then tested using an acoustic emission approach to obtain base acoustic emission response of short-term and severely-aged specimens. The remaining four specimens oven-aged for 36 hours were then treated by spreading their top surface with rejuvenator in the amount of 10% of the binder by weight. These four specimens were then tested using the same acoustic emission approach after two, four, six, and eight weeks of dwell time. It was observed that the embrittlement temperatures of the short-term aged and severely oven-aged specimens were -25 °C and - 15 °C, respectively. It was also observed that after four weeks of dwell time, the rejuvenator-treated samples had recuperated the original embrittlement temperatures. In addition, it was also observed that the rejuvenator kept acting upon the binder after four weeks of dwell time; at eight weeks of dwell time, the specimens had an embrittlement temperature about one grade cooler than the embrittlement temperature corresponding to the short-term aged specimen.

  15. Open-Ended Recursive Approach for the Calculation of Multiphoton Absorption Matrix Elements

    PubMed Central

    2015-01-01

    We present an implementation of single residues for response functions to arbitrary order using a recursive approach. Explicit expressions in terms of density-matrix-based response theory for the single residues of the linear, quadratic, cubic, and quartic response functions are also presented. These residues correspond to one-, two-, three- and four-photon transition matrix elements. The newly developed code is used to calculate the one-, two-, three- and four-photon absorption cross sections of para-nitroaniline and para-nitroaminostilbene, making this the first treatment of four-photon absorption in the framework of response theory. We find that the calculated multiphoton absorption cross sections are not very sensitive to the size of the basis set as long as a reasonably large basis set with diffuse functions is used. The choice of exchange–correlation functional, however, significantly affects the calculated cross sections of both charge-transfer transitions and other transitions, in particular, for the larger para-nitroaminostilbene molecule. We therefore recommend the use of a range-separated exchange–correlation functional in combination with the augmented correlation-consistent double-ζ basis set aug-cc-pVDZ for the calculation of multiphoton absorption properties. PMID:25821415

  16. Introduction to "Tsunamis in the Pacific Ocean: 2011-2012"

    NASA Astrophysics Data System (ADS)

    Rabinovich, Alexander B.; Borrero, Jose C.; Fritz, Hermann M.

    2014-12-01

    With this volume of the Pure and Applied Geophysics (PAGEOPH) topical issue "Tsunamis in the Pacific Ocean: 2011-2012", we are pleased to present 21 new papers discussing tsunami events occurring in this two-year span. Owing to the profound impact resulting from the unique crossover of a natural and nuclear disaster, research into the 11 March 2011 Tohoku, Japan earthquake and tsunami continues; here we present 12 papers related to this event. Three papers report on detailed field survey results and updated analyses of the wave dynamics based on these surveys. Two papers explore the effects of the Tohoku tsunami on the coast of Russia. Three papers discuss the tsunami source mechanism, and four papers deal with tsunami hydrodynamics in the far field or over the wider Pacific basin. In addition, a series of five papers presents studies of four new tsunami and earthquake events occurring over this time period. This includes tsunamis in El Salvador, the Philippines, Japan and the west coast of British Columbia, Canada. Finally, we present four new papers on tsunami science, including discussions on tsunami event duration, tsunami wave amplitude, tsunami energy and tsunami recurrence.

  17. Use of allopurinol with low-dose 6-mercaptopurine in inflammatory bowel disease to achieve optimal active metabolite levels: A review of four cases and the literature

    PubMed Central

    Witte, Todd N; Ginsberg, Allen L

    2008-01-01

    BACKGROUND: At least one-third of patients with inflammatory bowel disease do not respond or are intolerant to therapy with 6-mercaptopurine (6-MP). A subgroup fails to attain optimal levels of 6-thioguanine nucleotide (6-TGN) and instead shunts to 6-methylmercaptopurine nucleotide (6-MMPN). PATIENTS AND METHODS: A retrospective chart review was conducted, and four patients are described who had been previously unable to achieve optimal 6-TGN metabolite levels until allopurinol was added to their treatment. RESULTS: All four patients achieved optimal 6-TGN levels and undetectable 6-MMPN with a mean 6-MP dose of 0.49 mg/kg. Three achieved steroid-free clinical remission. Two of those three patients had normalization of liver enzymes; one patient had baseline normal liver enzymes despite an initial 6-MMPN level of 27,369 pmol/8×108 red blood cells. Two patients experienced reversible leukopenia. CONCLUSIONS: Combination allopurinol and low-dose 6-MP is an effective means to achieve optimal metabolite levels and steroid-free clinical remission in previously refractory patients. Caution is advised. PMID:18299738

  18. Screening study on microsphere used in profile control under the environment of microbial oil recovery

    NASA Astrophysics Data System (ADS)

    Zhang, Tiantian; Xie, Gang; Gao, Shanshan; Wang, Zhiqiang; Wei, Junjie; Shi, Lei; Zheng, Ya; Gu, Yi; Lei, Xiaoyang; Wang, Ai

    2017-12-01

    The performance of four microspheres samples (MS-1, MS-2, MS-3, and MS-4) were evaluated and optimized by indoor experiments. Firstly, the basic physical and chemical properties of the four kinds of microspheres were evaluated by analyzing the solid contents and the solubility in the water. Results showed that the content of the precipitated solids in MS-1 was the lowest in the four kinds of microsphere samples. The contents of the other three microspheres were similar in the value of solid content. Besides, the three microspheres of the solubility in the simulated formation water were excellent. Secondly, the expansion properties of three kinds of microspheres (MS-2, MS-3, and MS-4) were investigated. Results revealed that the expansion performance of MS-3 was greatly affected by microbial metabolism. However, the other two samples had excellent expansion performance under the condition of microbial flooding. Finally, the sealing performance of MS-2 and MS-4 was evaluated by physical simulation Block test. Results showed that compared with MS-2, MS-4 was more suitable for Block B.

  19. Is a Trineutron Resonance Lower in Energy than a Tetraneutron Resonance?

    NASA Astrophysics Data System (ADS)

    Gandolfi, S.; Hammer, H.-W.; Klos, P.; Lynn, J. E.; Schwenk, A.

    2017-06-01

    We present quantum Monte Carlo calculations of few-neutron systems confined in external potentials based on local chiral interactions at next-to-next-to-leading order in chiral effective field theory. The energy and radial densities for these systems are calculated in different external Woods-Saxon potentials. We assume that their extrapolation to zero external-potential depth provides a quantitative estimate of three- and four-neutron resonances. The validity of this assumption is demonstrated by benchmarking with an exact diagonalization in the two-body case. We find that the extrapolated trineutron resonance, as well as the energy for shallow well depths, is lower than the tetraneutron resonance energy. This suggests that a three-neutron resonance exists below a four-neutron resonance in nature and is potentially measurable. To confirm that the relative ordering of three- and four-neutron resonances is not an artifact of the external confinement, we test that the odd-even staggering in the helium isotopic chain is reproduced within this approach. Finally, we discuss similarities between our results and ultracold Fermi gases.

  20. Population and forensic data for three sets of forensic genetic markers in four ethnic groups from Iran: Persians, Lurs, Kurds and Azeris.

    PubMed

    Poulsen, L; Farzad, M Sharafi; Børsting, C; Tomas, C; Pereira, V; Morling, N

    2015-07-01

    A total of 255 individuals (Persians, Lurs, Kurds and Azeris) from Iran were typed for three sets of forensic genetic markers with the NGM SElect™, DIPplex(®) and Argus X-12 kits. Statistically significant deviations (P≤0.002) from Hardy-Weinberg expectations were observed for the insertion-deletion markers HLD97 and HLD93 after Holm-Šidák correction. Statistically significant (P<0.05) levels of linkage disequilibrium were observed between markers within two of the four studied X-chromosomal linkage groups. AMOVA analyses of the three sets of markers did not show population structure when the individuals were grouped according to their ethnic group. The Iranian population grouped closely to populations living geographically near to Iran based on pairwise FST distances. The matching probabilities ranged from 1 in 3.2×10(7) males by using haplotype frequencies of four X-chromosomal haplogroups to 1 in 3.4×10(21) individuals for the 16 autosomal STRs. Copyright © 2015. Published by Elsevier Ireland Ltd.

  1. Is a Trineutron Resonance Lower in Energy than a Tetraneutron Resonance?

    DOE PAGES

    Gandolfi, Stefano; Hammer, Hans -Werner; Klos, P.; ...

    2017-06-08

    Here, we present quantum Monte Carlo calculations of few-neutron systems confined in external potentials based on local chiral interactions at next-to-next-to-leading order in chiral effective field theory. The energy and radial densities for these systems are calculated in different external Woods-Saxon potentials. We assume that their extrapolation to zero external-potential depth provides a quantitative estimate of three- and four-neutron resonances. The validity of this assumption is demonstrated by benchmarking with an exact diagonalization in the two-body case. We find that the extrapolated trineutron resonance, as well as the energy for shallow well depths, is lower than the tetraneutron resonance energy.more » This suggests that a three-neutron resonance exists below a four-neutron resonance in nature and is potentially measurable. To confirm that the relative ordering of three- and four-neutron resonances is not an artifact of the external confinement, we test that the odd-even staggering in the helium isotopic chain is reproduced within this approach. Finally, we discuss similarities between our results and ultracold Fermi gases.« less

  2. Four-dimensional modulation and coding: An alternate to frequency-reuse

    NASA Technical Reports Server (NTRS)

    Wilson, S. G.; Sleeper, H. A.

    1983-01-01

    Four dimensional modulation as a means of improving communication efficiency on the band-limited Gaussian channel, with the four dimensions of signal space constituted by phase orthogonal carriers (cos omega sub c t and sin omega sub c t) simultaneously on space orthogonal electromagnetic waves are discussed. "Frequency reuse' techniques use such polarization orthogonality to reuse the same frequency slot, but the modulation is not treated as four dimensional, rather a product of two-d modulations, e.g., QPSK. It is well known that, higher dimensionality signalling affords possible improvements in the power bandwidth sense. Four-D modulations based upon subsets of lattice-packings in four-D, which afford simplification of encoding and decoding are described. Sets of up to 1024 signals are constructed in four-D, providing a (Nyquist) spectral efficiency of up to 10 bps/Hz. Energy gains over the reuse technique are in the one to three dB range t equal bandwidth.

  3. Four-dimensional modulation and coding - An alternate to frequency-reuse

    NASA Technical Reports Server (NTRS)

    Wilson, S. G.; Sleeper, H. A.; Srinath, N. K.

    1984-01-01

    Four dimensional modulation as a means of improving communication efficiency on the band-limited Gaussian channel, with the four dimensions of signal space constituted by phase orthogonal carriers (cos omega sub c t and sin omega sub c t) simultaneously on space orthogonal electromagnetic waves are discussed. 'Frequency reuse' techniques use such polarization orthogonality to reuse the same frequency slot, but the modulation is not treated as four dimensional, rather a product of two-D modulations, e.g., QPSK. It is well known that, higher dimensionality signalling affords possible improvements in the power bandwidth sense. Four-D modulations based upon subsets of lattice-packings in four-D, which afford simplification of encoding and decoding are described. Sets of up to 1024 signals are constructed in four-D, providing a (Nyquist) spectral efficiency of up to 10 bps/Hz. Energy gains over the reuse technique are in the one to three dB range t equal bandwidth.

  4. Black-hole/near-horizon-CFT duality and 4 dimensional classical spacetimes

    NASA Astrophysics Data System (ADS)

    Rodriguez, Leo L.

    2011-09-01

    In this thesis we accomplish two goals: We construct a two dimensional conformal field theory (CFT), in the form of a Liouville theory, in the near horizon limit for three and four dimensions black holes. The near horizon CFT assumes the two dimensional black hole solutions that were first introduced by Christensen and Fulling (1977 Phys. Rev. D 15 2088-104) and later expanded to a greater class of black holes via Robinson and Wilczek (2005 Phys. Rev. Lett. 95 011303). The two dimensions black holes admit a Diff( S1) or Witt subalgebra, which upon quantization in the horizon limit becomes Virasoro with calculable central charge. These charges and lowest Virasoro eigen-modes reproduce the correct Bekenstein-Hawking entropy of the four and three dimensions black holes via the Cardy formula (Blote et al 1986 Phys. Rev. Lett. 56 742; Cardy 1986 Nucl. Phys. B 270 186). Furthermore, the two dimensions CFT's energy momentum tensor is anomalous, i.e. its trace is nonzero. However, In the horizon limit the energy momentum tensor becomes holomorphic equaling the Hawking flux of the four and three dimensions black holes. This encoding of both entropy and temperature provides a uniformity in the calculation of black hole thermodynamics and statistical quantities for the non local effective action approach. We also show that the near horizon regime of a Kerr-Newman-AdS (KNAdS) black hole, given by its two dimensional analogue a la Robinson and Wilczek, is asymptotically AdS 2 and dual to a one dimensional quantum conformal field theory (CFT). The s-wave contribution of the resulting CFT's energy-momentum-tensor together with the asymptotic symmetries, generate a centrally extended Virasoro algebra, whose central charge reproduces the Bekenstein-Hawking entropy via Cardy's Formula. Our derived central charge also agrees with the near extremal Kerr/CFT Correspondence in the appropriate limits. We also compute the Hawking temperature of the KNAdS black hole by coupling its Robinson and Wilczek two dimensional analogue (RW2DA) to conformal matter.

  5. Learning Words and Definitions in Two Languages: What Promotes Cross-Language Transfer?

    ERIC Educational Resources Information Center

    Pham, Giang; Donovan, Danaee; Dam, Quynh; Contant, Amy

    2018-01-01

    This study used a brief vocabulary training paradigm to examine two factors for cross-language transfer: how similar the first language (L1) is to the second language (L2) and L1-L2 proficiency levels. Fifty-four sequential bilingual children (aged 6-8) with similar L2 English proficiency levels were assigned to three equal groups: a…

  6. SCDC Spanish Curricula Units. Social Science Strand, Unit 4, Grade Two, Teacher's Guide.

    ERIC Educational Resources Information Center

    Spanish Curricula Development Center, Miami Beach, FL.

    The Spanish-English teacher's guide to unit four of the bilingual social science program for second grade students contains instructional activities to expand the child's conceptual field to the neighborhood. Kits 13-16 include assessment activities; each kit is to be used for two to three weeks. Focus, objective, and materials are listed for each…

  7. Learning New Grammatical Structures in Task-Based Language Learning: The Effects of Recasts and Prompts

    ERIC Educational Resources Information Center

    Van de Guchte, Marrit; Braaksma, Martine; Rijlaarsdam, Gert; Bimmel, Peter

    2015-01-01

    In the present study, we examine the effects of prompts and recasts on the acquisition of two new and different grammar structures in a task-based learning environment. Sixty-four 14-year-old 9th grade students (low intermediate) learning German as a foreign language were randomly assigned to three conditions: two experimental groups (one…

  8. New and interesting ectomycorrhizal fungi from Puerto Rico, Mona, and Guana Islands

    Treesearch

    Orson K. Miller; D. Jean Lodge; Timothy J. Baroni

    2000-01-01

    A report of putative ectomycorrhizal fungi from Puerto Rico, Mona, and Guana Island in the Greater Antilles includes four species of Amanita, three of which are new species; two Lactarius, one is new, and two species of Boletus, one new. In addition, new distribution records of Phlebopus beniensis, Russula littoralis, Lactarius ferrugineus, a new small spored...

  9. Results of a Two-Year Longitudinal Study of Beverage-Specific Alcohol Use among Adolescents

    ERIC Educational Resources Information Center

    Moore, Michele Johnson; Werch, Chudley

    2007-01-01

    This study explored beverage-specific alcohol consumption patterns among a sample of high school students over a two-year period. Four hundred fifty-five students completed the validated questionnaire at all three time points (2002, 2003, 2004). Variables of interest included five use measures (past year use, 30-day frequency, quantity, heavy use,…

  10. Heat, Energy, and Order, Part Two of an Integrated Science Sequence, Teacher's Guide, 1970 Edition.

    ERIC Educational Resources Information Center

    Portland Project Committee, OR.

    This teacher's guide contains part two of the four-part first year Portland Project, a three-year secondary integrated science curriculum sequence. This part involves the student with unifying principles essential for deeper understanding of the concept of energy. Confidence in the atomic nature of matter is built by relating heat in terms of…

  11. Phenology and recruitment of Ohio buckeye and sugar maple in Illinois forest stands

    Treesearch

    Michelle Henderson; Jeffery O. Dawson; Evan H. DeLucia

    1993-01-01

    Phenological patterns, light conditions, and photosynthetic activity of Ohio buckeye and sugar maple foliage on trees in the forest understory were monitored and compared over two growing seasons in two mesophytic upland woodlands in central Illinois. Ohio buckeye began leaf expansion three to four weeks earlier than sugar maple, started leaf senescence and shedding in...

  12. Micro-Experimental Analysis of the Small-Group Reading Lesson: Social and Cognitive Consequences of Silent Reading.

    ERIC Educational Resources Information Center

    Wilkinson, Ian A. G.; Anderson, Richard C.

    This study examined a social-organizational hypothesis that explains how silent reading in small-group lessons might influence students' learning. One hundred children in four third-grade classes, each divided into three ability groups, received two silent and two oral reading lessons. Group dynamics were measured from videotapes of the lessons.…

  13. SCDC Spanish Curricula Units. Science/Math Strand, Unit 4, Grade Two, Teacher's Guide.

    ERIC Educational Resources Information Center

    Spanish Curricula Development Center, Miami Beach, FL.

    The teacher's guide for unit four of a Spanish science/math strand for second graders contains instructional and assessment activities for kits 13-16. Each designed for a two- to three-week teaching period, the kits' activities are geared toward guiding the child to discover correct answers through methods provided and, by putting materials in his…

  14. Seasonal branch and fine root growth of juvenile loblolly pine five growing seasons after fertilization

    Treesearch

    M.A. Sword; D.A. Gravatt; P.L. Faulkner; J.L. Chambers

    1996-01-01

    In 1989, we established two replications of two fertilization treatments in a 10-year-old loblolly pine (Pinus taeda L.) plantation. Between March and September 1993, branch internode and needle fascicle expansion in the upper and lower third of crowns were measured weekly on three south-facing branches of each of four trees, and new root...

  15. Production analysis of two tree-bucking and product-sorting methods for hardwoods

    Treesearch

    John E. Baumgras; Chris B. LeDoux

    1989-01-01

    This paper documents the results of a study to determine the cost and productivity of two tree-bucking and product-sorting methods used by West Virginia loggers harvesting three to four types of roundwood products. The methods include manual chainsaw bucking and bucking with a hydraulically powered chainsaw slasher. Results show that chain saw bucking of trees...

  16. Army National Guard Companies Have Not Developed Effective Training Programs to Attain or Sustain Mission Essential Task Proficiency (REDACTED)

    DTIC Science & Technology

    2016-12-05

    consist of at least five company -level units: headquarters , two rifle, and two armored units. Reconnaissance squadrons generally consist of at...least four company - level units: headquarters and three reconnaissance units...Brief (U) Army National Guard Companies Have Not Developed Effective Training Programs to Attain or Sustain Mission Essential Task Proficiency

  17. An Exploratory Examination of Families Engaged in a Children's Adventure Running Program

    ERIC Educational Resources Information Center

    Isnor, Heather; Dawson, Kimberley A.

    2017-01-01

    The purpose of this study was to qualitatively explore the experiences of families who participated in an adventure running program (ARP) in Canada. Adventure running is a unique sport that combines navigation and running in a forested setting. Six parents (four males, two females) and five children (two females, three males) were interviewed.…

  18. Two-year results of herbicide released, naturally-regenerated bottomland cherrybark and shumard oak seedlings

    Treesearch

    John F., Jr. Thompson; Larry E. Nix

    1995-01-01

    After clearcuting in bottomlands, oak seedlings that naturally regenerate are often overtopped by woody pioneer species, sprouts and herbaceous material. To improve the competitive status of three- to four-year-old oak seedlings in two bottomland stands in South Carolina, several herbicides and methods of application were used to kill and/or stunt the overtopping...

  19. The Arizona Board of Regents' Task Force on Excellence, Efficiency and Competitiveness. The Final Report and Working Papers. Volume Two.

    ERIC Educational Resources Information Center

    Arizona Board of Regents, Phoenix.

    Volume Two of a report by the Arizona Board of Regents' independent citizen commission to examine the performance of the state's three public universities presents 26 working papers in four sections. Section One, Research and Graduate Education/Universities: A State Resource, offers five papers, including: "University Research and Economic…

  20. Waves and Particles, The Orbital Atom, Parts One and Two of an Integrated Science Sequence, Teacher's Guide, 1973 Edition.

    ERIC Educational Resources Information Center

    Portland Project Committee, OR.

    This teacher's guide includes parts one and two of the four-part third year Portland Project, a three-year integrated secondary science curriculum sequence. The Harvard Project Physics textbook is used for reading assignments for part one. Assignments relate to waves, light, electricity, magnetic fields, Faraday and the electrical age,…

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