Sample records for typically developing comparison

  1. Mealtime Behaviors of Preschool Children: Comparison of Children with Autism Spectrum Disorder and Children with Typical Development

    ERIC Educational Resources Information Center

    Provost, Beth; Crowe, Terry K.; Osbourn, Patricia L.; McClain, Catherine; Skipper, Betty J.

    2010-01-01

    This study identified mealtime behaviors of young children (3-6 years old) with autism spectrum disorder (ASD) and compared these behaviors to children with typical development matched for age, gender, and ethnicity. The parents of children with ASD (n = 24) and children with typical development (n = 24) completed a mealtime survey to assess early…

  2. A Dyadic Analysis of the Effects of Setting and Communication Partner on Elicited and Spontaneous Communication of Children with Autism Spectrum Disorder and Typically Developing Children

    ERIC Educational Resources Information Center

    Forde, Ita; Holloway, Jennifer; Healy, Olive; Brosnan, Julie

    2011-01-01

    The study examined the effects of condition and communication partner on spontaneous and elicited communication in children with Autism Spectrum Disorder (ASD) in comparison to age matched typically developing children. Eighteen children participated in the study (nine children diagnosed with ASD and nine typically developing children). Each…

  3. Is lower IQ in children with epilepsy due to lower parental IQ? A controlled comparison study

    PubMed Central

    Walker, Natalie M; Jackson, Daren C; Dabbs, Kevin; Jones, Jana E; Hsu, David A; Stafstrom, Carl E; Sheth, Raj D; Koehn, Monica A; Seidenberg, Michael; Hermann, Bruce P

    2012-01-01

    Aim The aim of this study was to determine the relationship between parent and child full-scale IQ (FSIQ) in children with epilepsy and in typically developing comparison children and to examine parent–child IQ differences by epilepsy characteristics. Method The study participants were 97 children (50 males, 47 females; age range 8–18y; mean age 12y 3mo, SD 3y.1mo) with recent-onset epilepsy including idiopathic generalized (n=43) and idiopathic localization-related epilepsies (n=54); 69 healthy comparison children (38 females, 31 males; age range 8–18y; mean age 12y 8mo, SD 3y 2mo), and one biological parent per child. All participants were administered the Wechsler Abbreviated Intelligence Scale. FSIQ was compared in children with epilepsy and typically developing children; FSIQ was compared in the parents of typically developing children and the parents of participants with epilepsy; parent–child FSIQ differences were compared between the groups. Results FSIQ was lower in children with epilepsy than in comparison children (p<0.001). FSIQ of parents of children with epilepsy did not differ from the FSIQ of the parents of typically developing children. Children with epilepsy had significantly lower FSIQ than their parents (p<0.001), whereas comparison children did not. The parent–child IQ difference was significantly higher in the group with epilepsy than the comparison group (p=0.043). Epilepsy characteristics were not related to parent–child IQ difference. Interpretation Parent–child IQ difference appears to be a marker of epilepsy impact independent of familial IQ, epilepsy syndrome, and clinical seizure features. This marker is evident early in the course of idiopathic epilepsies and can be tracked over time. PMID:23216381

  4. Functional magnetic resonance imaging of story listening in adolescents and young adults with Down syndrome: evidence for atypical neurodevelopment.

    PubMed

    Jacola, L M; Byars, A W; Hickey, F; Vannest, J; Holland, S K; Schapiro, M B

    2014-10-01

    Previous studies have documented differences in neural activation during language processing in individuals with Down syndrome (DS) in comparison with typically developing individuals matched for chronological age. This study used functional magnetic resonance imaging (fMRI) to compare activation during language processing in young adults with DS to typically developing comparison groups matched for chronological age or mental age. We hypothesised that the pattern of neural activation in the DS cohort would differ when compared with both typically developing cohorts. Eleven persons with DS (mean chronological age = 18.3; developmental age range = 4-6 years) and two groups of typically developing individuals matched for chronological (n = 13; mean age = 18.3 years) and developmental (mental) age (n = 12; chronological age range = 4-6 years) completed fMRI scanning during a passive story listening paradigm. Random effects group comparisons were conducted on individual maps of the contrast between activation (story listening) and rest (tone presentation) conditions. Robust activation was seen in typically developing groups in regions associated with processing auditory information, including bilateral superior and middle temporal lobe gyri. In contrast, the DS cohort demonstrated atypical spatial distribution of activation in midline frontal and posterior cingulate regions when compared with both typically developing control groups. Random effects group analyses documented reduced magnitude of activation in the DS cohort when compared with both control groups. Activation in the DS group differed significantly in magnitude and spatial extent when compared with chronological and mental age-matched typically developing control groups during a story listening task. Results provide additional support for an atypical pattern of functional organisation for language processing in this population. © 2013 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

  5. A Comparison of the Development of Audiovisual Integration in Children with Autism Spectrum Disorders and Typically Developing Children

    ERIC Educational Resources Information Center

    Taylor, Natalie; Isaac, Claire; Milne, Elizabeth

    2010-01-01

    This study aimed to investigate the development of audiovisual integration in children with Autism Spectrum Disorder (ASD). Audiovisual integration was measured using the McGurk effect in children with ASD aged 7-16 years and typically developing children (control group) matched approximately for age, sex, nonverbal ability and verbal ability.…

  6. Young Friendship in HFASD and Typical Development: Friend versus Non-Friend Comparisons

    ERIC Educational Resources Information Center

    Bauminger-Zviely, Nirit; Agam-Ben-Artzi, Galit

    2014-01-01

    This study conducted comparative assessment of friendship in preschoolers with high-functioning autism spectrum disorder (HFASD, n = 29) versus preschoolers with typical development (n = 30), focusing on interactions with friends versus acquaintances. Groups were matched on SES, verbal/nonverbal MA, IQ, and CA. Multidimensional assessments…

  7. The Peer Social Networks of Young Children with Down Syndrome in Classroom Programmes

    ERIC Educational Resources Information Center

    Guralnick, Michael J.; Connor, Robert T.; Johnson, L. Clark

    2011-01-01

    Background: The nature and characteristics of the peer social networks of young children with Down syndrome (DS) in classroom settings were examined within a developmental framework. Method: Comparisons were made with younger typically developing children matched on mental age and typically developing children matched on chronological age.…

  8. Semantic Abilities in Children with Pragmatic Language Impairment: The Case of Picture Naming Skills

    ERIC Educational Resources Information Center

    Ketelaars, Mieke Pauline; Hermans, Suzanne Irene Alphonsus; Cuperus, Juliane; Jansonius, Kino; Verhoeven, Ludo

    2011-01-01

    Purpose: The semantic abilities of children with pragmatic language impairment (PLI) are subject to debate. The authors investigated picture naming and definition skills in 5-year-olds with PLI in comparison to typically developing children. Method: 84 children with PLI and 80 age-matched typically developing children completed receptive…

  9. Representing Intentions in Self and Other: Studies of Autism and Typical Development

    ERIC Educational Resources Information Center

    Williams, David; Happe, Francesca

    2010-01-01

    Two experiments were conducted to explore the extent to which individuals with Autism Spectrum Disorder (ASD), as well as young typically developing (TD) children, are explicitly aware of their own and others' intentions. In Experiment 1, participants with ASD were significantly less likely than age- and ability-matched comparison participants to…

  10. Scaling of Performance in Liquid Propellant Rocket Engine Combustors

    NASA Technical Reports Server (NTRS)

    Hulka, James R.

    2007-01-01

    This paper discusses scaling of combustion and combustion performance in liquid propellant rocket engine combustion devices. In development of new combustors, comparisons are often made between predicted performance in a new combustor and measured performance in another combustor with different geometric and thermodynamic characteristics. Without careful interpretation of some key features, the comparison can be misinterpreted and erroneous information used in the design of the new device. This paper provides a review of this performance comparison, including a brief review of the initial liquid rocket scaling research conducted during the 1950s and 1960s, a review of the typical performance losses encountered and how they scale, a description of the typical scaling procedures used in development programs today, and finally a review of several historical development programs to see what insight they can bring to the questions at hand.

  11. Scaling of Performance in Liquid Propellant Rocket Engine Combustion Devices

    NASA Technical Reports Server (NTRS)

    Hulka, James R.

    2008-01-01

    This paper discusses scaling of combustion and combustion performance in liquid propellant rocket engine combustion devices. In development of new combustors, comparisons are often made between predicted performance in a new combustor and measured performance in another combustor with different geometric and thermodynamic characteristics. Without careful interpretation of some key features, the comparison can be misinterpreted and erroneous information used in the design of the new device. This paper provides a review of this performance comparison, including a brief review of the initial liquid rocket scaling research conducted during the 1950s and 1960s, a review of the typical performance losses encountered and how they scale, a description of the typical scaling procedures used in development programs today, and finally a review of several historical development programs to see what insight they can bring to the questions at hand.

  12. The Impact of Executive Function Skills on Writing: A Comparison of Fifth-Grade Students with Learning Disabilities and Students with Typical Development

    ERIC Educational Resources Information Center

    Nathan, Anne Michelle

    2009-01-01

    This study explored the relationship between verbal fluency skills and writing skills in developing writers. There were three research questions addressed: (1) Was there a difference between fifth-grade students who have a learning disability (LD) in written language and fifth-grade students with typical development (TD) on the Delis-Kaplan…

  13. Sleep and Daytime Functioning: A Short-Term Longitudinal Study of Three Preschool-Age Comparison Groups

    ERIC Educational Resources Information Center

    Anders, Thomas; Iosif, Ana-Maria; Schwichtenberg, A. J.; Tang, Karen; Goodlin-Jones, Beth

    2012-01-01

    This study examined sleep, sleepiness, and daytime performance in 68 children with autism, 57 children with intellectual disability (ID), and 69 typically developing preschool children. Children in the autism and ID groups had poorer daytime performance and behaviors than the typically developing children. Children in the ID group also were…

  14. Comparison of Physical Activity between Children with Autism Spectrum Disorders and Typically Developing Children

    ERIC Educational Resources Information Center

    Bandini, Linda G.; Gleason, James; Curtin, Carol; Lividini, Keith; Anderson, Sarah E.; Cermak, Sharon A.; Maslin, Melissa; Must, Aviva

    2013-01-01

    Regular physical activity is important for promoting health and well-being; however, physical activity behaviors in children with autism spectrum disorders (ASD) have received little attention. We compared physical activity levels among 53 children with ASD and 58 typically developing children aged 3-11 years who participated in the Children's…

  15. Mealtime Problems in Children with Autism Spectrum Disorder and Their Typically Developing Siblings: A Comparison Study

    ERIC Educational Resources Information Center

    Nadon, Genevieve; Feldman, Debbie Ehrmann; Dunn, Winnie; Gisel, Erika

    2011-01-01

    Many children with autism spectrum disorders (ASD) have mealtime problems. Diagnosis and the social environment may influence eating behaviours. We examined whether children with ASD have more mealtime problems than their typically developing siblings, and whether age and sex are associated with mealtime problems. Forty-eight families participated…

  16. Investigation of language and motor skills in Serbian speaking children with specific language impairment and in typically developing children.

    PubMed

    Vukovic, Mile; Vukovic, Irena; Stojanovik, Vesna

    2010-01-01

    Specific language impairment (SLI) is usually defined as a developmental language disorder which does not result from a hearing loss, autism, neurological and emotional difficulties, severe social deprivation, low non-verbal abilities. Children affected with SLI typically have difficulties with the acquisition of different aspects of language and by definition, their impairment is specific to language and no other skills are affected. However, there has been a growing body of literature to suggest that children with SLI also have non-linguistic deficits, including impaired motor abilities. The aim of the current study is to investigate language and motor abilities of a group of thirty children with SLI (aged between 4 and 7) in comparison to a group of 30 typically developing children matched for chronological age. The results showed that the group of children with SLI had significantly more difficulties on the language and motor assessments compared to the control group. The SLI group also showed delayed onset in the development of all motor skills under investigation in comparison to the typically developing group. More interestingly, the two groups differed with respect to which language abilities were correlated with motor abilities, however Imitation of Complex Movements was the unique skill which reliably predicted expressive vocabulary in both typically developing children and in children with SLI. Copyright © 2010 Elsevier Ltd. All rights reserved.

  17. Comparison of Sedentary Behaviors between Children with Autism Spectrum Disorders and Typically Developing Children

    ERIC Educational Resources Information Center

    Must, Aviva; Phillips, Sarah M.; Curtin, Carol; Anderson, Sarah E.; Maslin, Melissa; Lividini, Keith; Bandini, Linda G.

    2014-01-01

    Time spent in sedentary behavior is largely due to time spent engaged with electronic screen media. Little is known about the extent to which sedentary behaviors for children with autism spectrum disorder differ from typically developing children. We used parental report to assess and compare time spent in sedentary behaviors for 53 children with…

  18. Sex Differences in Children with Autism Spectrum Disorders Compared with Their Unaffected Siblings and Typically Developing Children

    ERIC Educational Resources Information Center

    Park, Subin; Cho, Soo-Churl; Cho, In Hee; Kim, Boong-Nyun; Kim, Jae-Won; Shin, Min-Sup; Chung, Un-Sun; Park, Tae-Won; Son, Jung-Woo; Yoo, Hee Jeong

    2012-01-01

    This study examined the nature of cognitive and behavioral sex differences in children with autism spectrum disorders (ASDs) and two comparison groups: a group of typically developing (TD) children and a group of unaffected siblings of ASD children. Sex differences in core autistic symptoms, co-occurring behavioral symptoms, and cognitive styles…

  19. Parenting a Child with ASD: Comparison of Parenting Style between ASD, Anxiety, and Typical Development

    ERIC Educational Resources Information Center

    Ventola, Pamela; Lei, Jiedi; Paisley, Courtney; Lebowitz, Eli; Silverman, Wendy

    2017-01-01

    Parenting children with ASD has a complex history. Given parents' increasingly pivotal role in children's treatment, it is critical to consider parental style and behaviours. This study (1) compares parenting style of parents of children with ASD, parents of children with anxiety disorders, and parents of typically developing (TD) children and (2)…

  20. Comparison of Nutritional Status between Children with Autism Spectrum Disorder and Typically Developing Children in the Mediterranean Region (Valencia, Spain)

    ERIC Educational Resources Information Center

    Marí-Bauset, Salvador; Llopis-González, Agustín; Zazpe, Itziar; Marí-Sanchis, Amelia; Morales Suárez-Varela, Maria

    2017-01-01

    This case-control study investigated nutrient intake, healthy eating index with 10 items on foods and nutrients, on 3-day food diaries and anthropometric measurements in 105 children with autism spectrum disorder and 495 typically developing children (6-9 years) in Valencia (Spain). Children with autism spectrum disorder were at a higher risk for…

  1. Joint Attention in Parent-Child Dyads Involving Children with Selective Mutism: A Comparison between Anxious and Typically Developing Children

    ERIC Educational Resources Information Center

    Nowakowski, Matilda E.; Tasker, Susan L.; Cunningham, Charles E.; McHolm, Angela E.; Edison, Shannon; St. Pierre, Jeff; Boyle, Michael H.; Schmidt, Louis A.

    2011-01-01

    Although joint attention processes are known to play an important role in adaptive social behavior in typical development, we know little about these processes in clinical child populations. We compared early school age children with selective mutism (SM; n = 19) versus mixed anxiety (MA; n = 18) and community controls (CC; n = 26) on joint…

  2. Outcome and Process in Motor Performance: A Comparison of Jumping by Typically Developing Children and Those with Low Motor Proficiency

    ERIC Educational Resources Information Center

    Williams, Morgan D.; Saunders, John E.; Maschette, Wayne E.; Wilson, Cameron J.

    2013-01-01

    The motivation for this study was to explore a conceptual framework to understand the outcomes and processes of motor performance in children. Vertical jumping, a fundamental movement skill, was used to compare children (ages 6-12 years) who were typically developing (TD) and those identified as having low motor proficiency (LMP). Jumps were…

  3. Parenting in Families with a Child with Autism Spectrum Disorder and a Typically Developing Child: Mothers' Experiences and Cognitions

    ERIC Educational Resources Information Center

    Meirsschaut, Mieke; Roeyers, Herbert; Warreyn, Petra

    2010-01-01

    The parenting experiences of mothers in a family with a child with autism spectrum disorder (ASD) and a typically developing (TD) child were studied using a qualitative analysis of mothers' perceptions of the impact of autism on family and personal life. An additional quantitative comparison was performed to evaluate the effect of ASD on mothers'…

  4. Perceptions of Distress in Young Children with Autism Compared to Typically Developing Children: A Cultural Comparison between Japan and Italy

    ERIC Educational Resources Information Center

    Esposito, G.; Nakazawa, J.; Venuti, P.; Bornstein, M. H.

    2012-01-01

    This study investigates how adults in two contrasting cultures (Italian and Japanese) perceive episodes of crying of typically developing (TD) children and children with Autism Disorder (AD). Although cries of children with AD have been reported to elicit more distress in Western cultures, it is not known whether similar findings hold in Eastern…

  5. The Effect of Activity with E-Book on Vocabulary and Story Comprehension: A Comparison between Kindergarteners at Risk of Learning Disabilities and Typically Developing Kindergarteners

    ERIC Educational Resources Information Center

    Shamir, Adina; Korat, Ofra; Shlafer, Inessa

    2011-01-01

    The purpose of the current study was to investigate the effectiveness of e-book activity for vocabulary acquisition and story comprehension among kindergarteners at risk for learning disabilities (LD) as opposed to typically developing (TD) children. Participants included 136 children aged between five and seven (M = 71.2; SD = 5.64, in months),…

  6. Development of light and small airplanes

    NASA Technical Reports Server (NTRS)

    Lachmann, G

    1926-01-01

    The author has endeavored to select only the most important lines of development and has limited the description of individual airplanes to a few typical examples. Comparisons are presented between German and foreign accomplishments.

  7. Toddlers' categorization of typical and scrambled dolls and cars.

    PubMed

    Heron, Michelle; Slaughter, Virginia

    2008-09-01

    Previous research has demonstrated discrimination of scrambled from typical human body shapes at 15-18 months of age [Slaughter, V., & Heron, M. (2004). Origins and early development of human body knowledge. Monographs of the Society for Research in Child Development, 69]. In the current study 18-, 24- and 30-month-old infants were presented with four typical and four scrambled dolls in a sequential touching procedure, to assess the development of explicit categorization of human body shapes. Infants were also presented with typical and scrambled cars, allowing comparison of infants' categorization of scrambled and typical exemplars in a different domain. Spontaneous comments regarding category membership were recorded. Girls categorized dolls and cars as typical or scrambled at 30 months, whereas boys only categorized the cars. Earliest categorization was for typical and scrambled cars, at 24 months, but only for boys. Language-based knowledge, coded from infants' comments, followed the same pattern. This suggests that human body knowledge does not have privileged status in infancy. Gender differences in performance are discussed.

  8. Topical Review: Integrating Findings on Direct Observation of Family Communication in Studies Comparing Pediatric Chronic Illness and Typically Developing Samples.

    PubMed

    Murphy, Lexa K; Murray, Caitlin B; Compas, Bruce E

    2017-01-01

    To review research on observed family communication in families with children with chronic illnesses compared with families with healthy, typically developing children, and to integrate findings utilizing a unifying family communication framework. Topical review of studies that have directly observed family communication in pediatric populations and included a typically developing comparison group. Initial findings from 14 studies with diverse approaches to quantifying observed family communication suggest that families with children with chronic illnesses may demonstrate lower levels of warm and structured communication and higher levels of hostile/intrusive and withdrawn communication compared with families with healthy, typically developing children. An integrative framework of family communication may be used in future studies that examine the occurrence, correlates, and mechanisms of family communication in pediatric populations.

  9. Autonomic Dysregulation during Sensory Stimulation in Children with Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    Schaaf, Roseann C.; Benevides, Teal W.; Leiby, Benjamin E.; Sendecki, Jocelyn A.

    2015-01-01

    Autonomic nervous system (ANS) activity during sensory stimulation was measured in 59 children with autism spectrum disorder (ASD) ages 6-9 in comparison to 30 typically developing controls. Multivariate comparisons revealed significant differences between groups in the respiratory sinus arrhythmia (parasympathetic measure) vector of means across…

  10. Personality Dimensions, Religious Tendencies and Coping Strategies as Predictors of General Health in Iranian Mothers of Children with Intellectual Disability: A Comparison with Mothers of Typically Developing Children

    ERIC Educational Resources Information Center

    Mirsaleh, Y. R.; Rezai, H.; Khabaz, M.; Afkhami Ardekani, I.; Abdi, K.

    2011-01-01

    Background: Challenges related to rearing children with intellectual disability (ID) may cause mothers of these children to have mental health status problems. Method: A total of 124 mothers who had a child with ID and 124 mothers of typically developing children were selected using random sampling. Data were collected using General health…

  11. Performance of motor imitation in children with and without dyspraxia.

    PubMed

    Ruttanathantong, Korrawan; Siritaratiwat, Wantana; Sriphetcharawut, Sarinya; Emasithi, Alongkot; Saengsuwan, Jiamjit; Saengsuwan, Jittima

    2013-07-01

    Motor imitation is truly essential for young children to learn new motor skills, social behavior and skilled acts or praxis. The present study aimed to investigate motor imitation ability between typically-developing children and dyspraxic children and to examine the development trends in both children groups. The comparison ofmotor imitation was studied in 55 typically-developing children and 59 dyspraxic children aged 5 to 8 years. The Motor Imitation subtest consisted of two sections, imitation of postures and imitation of verbal instructions. Typically-developing children and dyspraxic children were examined for developmental trends. The independent samples t-test was used to analyze the differences between both groups. Two-way analysis of variance (ANOVA) was used to analyze inter-age differences for each age group. The results revealed significant differences between dyspraxic and typically-developing children. Both typically-developing and dyspraxic children demonstrated age trends. The older children scored higher than younger children. Imitation is a primary learning strategy of young children. It is essential that children with dyspraxia receive early detection and need effective intervention. Typically-developing children and dyspraxic children showed higher mean score on the Imitation of Posture section than the Verbal Instructions section. Motor imitation competency, therefore, changes and improves with age.

  12. Research on private cloud computing based on analysis on typical opensource platform: a case study with Eucalyptus and Wavemaker

    NASA Astrophysics Data System (ADS)

    Yu, Xiaoyuan; Yuan, Jian; Chen, Shi

    2013-03-01

    Cloud computing is one of the most popular topics in the IT industry and is recently being adopted by many companies. It has four development models, as: public cloud, community cloud, hybrid cloud and private cloud. Except others, private cloud can be implemented in a private network, and delivers some benefits of cloud computing without pitfalls. This paper makes a comparison of typical open source platforms through which we can implement a private cloud. After this comparison, we choose Eucalyptus and Wavemaker to do a case study on the private cloud. We also do some performance estimation of cloud platform services and development of prototype software as cloud services.

  13. PFLOTRAN-RepoTREND Source Term Comparison Summary.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Frederick, Jennifer M.

    Code inter-comparison studies are useful exercises to verify and benchmark independently developed software to ensure proper function, especially when the software is used to model high-consequence systems which cannot be physically tested in a fully representative environment. This summary describes the results of the first portion of the code inter-comparison between PFLOTRAN and RepoTREND, which compares the radionuclide source term used in a typical performance assessment.

  14. Adolescent Siblings of Individuals with Intellectual Disabilities with and without Comorbid Mental Health Problems: A Preliminary Comparison of Sibling Perceptions

    ERIC Educational Resources Information Center

    Shivers, Carolyn M.; Kozimor, Laura Michelle

    2017-01-01

    Introduction: The presence of comorbid mental illness in individuals with intellectual and developmental disabilities (IDD) has been shown to have additional negative impact on parents and caregivers. However, the impact of such dual diagnoses on typically developing siblings has yet to be examined. Methods: Parents and typically developing…

  15. A Comparison of Topography-Based and Selection-Based Verbal Behavior in Typically Developed Children and Developmentally Disabled Persons with Autism

    ERIC Educational Resources Information Center

    Vignes, Tore

    2007-01-01

    This study is a replication of Sundberg and Sundberg (1990) that compared topography-based verbal behavior with selection-based verbal behavior in terms of acquisition, accuracy, and testing for the emergence of a new verbal relation. Participants were three typical children and three developmentally disabled persons with autism. The study sought…

  16. Comparison of visual sensitivity to human and object motion in autism spectrum disorder.

    PubMed

    Kaiser, Martha D; Delmolino, Lara; Tanaka, James W; Shiffrar, Maggie

    2010-08-01

    Successful social behavior requires the accurate detection of other people's movements. Consistent with this, typical observers demonstrate enhanced visual sensitivity to human movement relative to equally complex, nonhuman movement [e.g., Pinto & Shiffrar, 2009]. A psychophysical study investigated visual sensitivity to human motion relative to object motion in observers with autism spectrum disorder (ASD). Participants viewed point-light depictions of a moving person and, for comparison, a moving tractor and discriminated between coherent and scrambled versions of these stimuli in unmasked and masked displays. There were three groups of participants: young adults with ASD, typically developing young adults, and typically developing children. Across masking conditions, typical observers showed enhanced visual sensitivity to human movement while observers in the ASD group did not. Because the human body is an inherently social stimulus, this result is consistent with social brain theories [e.g., Pelphrey & Carter, 2008; Schultz, 2005] and suggests that the visual systems of individuals with ASD may not be tuned for the detection of socially relevant information such as the presence of another person. Reduced visual sensitivity to human movements could compromise important social behaviors including, for example, gesture comprehension.

  17. A comparison of three approaches for simulating fine-scale surface winds in support of wildland fire management: Part I. Model formulation and comparison against measurements

    Treesearch

    Jason M. Forthofer; Bret W. Butler; Natalie S. Wagenbrenner

    2014-01-01

    For this study three types of wind models have been defined for simulating surface wind flow in support of wildland fire management: (1) a uniform wind field (typically acquired from coarse-resolution (,4 km) weather service forecast models); (2) a newly developed mass-conserving model and (3) a newly developed mass and momentumconserving model (referred to as the...

  18. Comparisons of anomalous and collisional radial transport with a continuum kinetic edge code

    NASA Astrophysics Data System (ADS)

    Bodi, K.; Krasheninnikov, S.; Cohen, R.; Rognlien, T.

    2009-05-01

    Modeling of anomalous (turbulence-driven) radial transport in controlled-fusion plasmas is necessary for long-time transport simulations. Here the focus is continuum kinetic edge codes such as the (2-D, 2-V) transport version of TEMPEST, NEO, and the code being developed by the Edge Simulation Laboratory, but the model also has wider application. Our previously developed anomalous diagonal transport matrix model with velocity-dependent convection and diffusion coefficients allows contact with typical fluid transport models (e.g., UEDGE). Results are presented that combine the anomalous transport model and collisional transport owing to ion drift orbits utilizing a Krook collision operator that conserves density and energy. Comparison is made of the relative magnitudes and possible synergistic effects of the two processes for typical tokamak device parameters.

  19. Atypical development of configural face recognition in children with autism, Down syndrome and Williams syndrome.

    PubMed

    Dimitriou, D; Leonard, H C; Karmiloff-Smith, A; Johnson, M H; Thomas, M S C

    2015-05-01

    Configural processing in face recognition is a sensitivity to the spacing between facial features. It has been argued both that its presence represents a high level of expertise in face recognition, and also that it is a developmentally vulnerable process. We report a cross-syndrome investigation of the development of configural face recognition in school-aged children with autism, Down syndrome and Williams syndrome compared with a typically developing comparison group. Cross-sectional trajectory analyses were used to compare configural and featural face recognition utilising the 'Jane faces' task. Trajectories were constructed linking featural and configural performance either to chronological age or to different measures of mental age (receptive vocabulary, visuospatial construction), as well as the Benton face recognition task. An emergent inversion effect across age for detecting configural but not featural changes in faces was established as the marker of typical development. Children from clinical groups displayed atypical profiles that differed across all groups. We discuss the implications for the nature of face processing within the respective developmental disorders, and how the cross-sectional syndrome comparison informs the constraints that shape the typical development of face recognition. © 2014 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

  20. Delayed matching to two-picture samples by individuals with and without disabilities: an analysis of the role of naming.

    PubMed

    Gutowski, Stanley J; Stromer, Robert

    2003-01-01

    Delayed matching to complex, two-picture samples (e.g., cat-dog) may be improved when the samples occasion differential verbal behavior. In Experiment 1, individuals with mental retardation matched picture comparisons to identical single-picture samples or to two-picture samples, one of which was identical to a comparison. Accuracy scores were typically high on single-picture trials under both simultaneous and delayed matching conditions. Scores on two-picture trials were also high during the simultaneous condition but were lower during the delay condition. However, scores improved on delayed two-picture trials when each of the sample pictures was named aloud before comparison responding. Experiment 2 replicated these results with preschoolers with typical development and a youth with mental retardation. Sample naming also improved the preschoolers' matching when the samples were pairs of spoken names and the correct comparison picture matched one of the names. Collectively, the participants could produce the verbal behavior that might have improved performance, but typically did not do so unless the procedure required it. The success of the naming intervention recommends it for improving the observing and remembering of multiple elements of complex instructional stimuli.

  1. Numerical magnitude processing in children with mild intellectual disabilities.

    PubMed

    Brankaer, Carmen; Ghesquière, Pol; De Smedt, Bert

    2011-01-01

    The present study investigated numerical magnitude processing in children with mild intellectual disabilities (MID) and examined whether these children have difficulties in the ability to represent numerical magnitudes and/or difficulties in the ability to access numerical magnitudes from formal symbols. We compared the performance of 26 children with MID on a symbolic (digits) and a non-symbolic (dot-arrays) comparison task with the performance of two control groups of typically developing children: one group matched on chronological age and one group matched on mathematical ability level. Findings revealed that children with MID performed more poorly than their typically developing chronological age-matched peers on both the symbolic and non-symbolic comparison tasks, while their performance did not substantially differ from the ability-matched control group. These findings suggest that the development of numerical magnitude representation in children with MID is marked by a delay. This performance pattern was observed for both symbolic and non-symbolic comparison tasks, although difficulties on the former task were more prominent. Interventions in children with MID should therefore foster both the development of magnitude representations and the connections between symbols and the magnitudes they represent. Copyright © 2011 Elsevier Ltd. All rights reserved.

  2. Gesture Production in School vs. Clinical Samples of Children with Developmental Coordination Disorder (DCD) and Typically Developing Children

    ERIC Educational Resources Information Center

    Sinani, Charikleia; Sugden, David A.; Hill, Elisabeth L.

    2011-01-01

    Dyspraxia, a difficulty in executing an operationalised act, has been associated with Developmental Coordination Disorder (DCD). However, issues relating to the area such as comparisons across modalities, comparisons of school vs. clinical populations, and developmental delay vs. pathology have not been addressed in the same, comprehensive study.…

  3. Morphology and Syntax in Late Talkers at Age 5

    ERIC Educational Resources Information Center

    Rescorla, Leslie; Turner, Hannah L.

    2015-01-01

    Purpose: This study reports age 5 morphology and syntax skills in late talkers identified at age 2 (n = 34) and typically developing comparison children (n = 20). Results: The late talkers manifested significant morphological delays at ages 3 and 4 relative to comparison peers. Based on the 14 morphemes analyzed at age 5, the only significant…

  4. Collaboration in Referential Communication: Comparison of Youth with Down Syndrome or Fragile X Syndrome

    ERIC Educational Resources Information Center

    Abbeduto, Leonard; Murphy, Melissa M.; Richmond, Erica K.; Amman, Adrienne; Beth, Patti; Weissman, Michelle D.; Kim, Jee-Seon; Cawthon, Stephanie W.; Karadottir, Selma

    2006-01-01

    Referential communication was examined in youth with Down syndrome or fragile X syndrome in comparison to each other and to MA-matched typically developing children. A non-face-to-face task was used in which the participant repeatedly described novel shapes to listeners. Several dimensions of referential communication were especially challenging…

  5. Inversion Effects in the Perception of the Moving Human Form: A Comparison of Adolescents with Autism Spectrum Disorder and Typically Developing Adolescents

    ERIC Educational Resources Information Center

    Cleary, Laura; Looney, Kathy; Brady, Nuala; Fitzgerald, Michael

    2014-01-01

    The "body inversion effect" refers to superior recognition of upright than inverted images of the human body and indicates typical configural processing. Previous research by Reed et al. using static images of the human body shows that people with autism fail to demonstrate this effect. Using a novel task in which adults, adolescents…

  6. Vocal and Gestural Productions of 24-Month-Old Children with Sex Chromosome Trisomies

    ERIC Educational Resources Information Center

    Zampini, Laura; Draghi, Lara; Silibello, Gaia; Dall'Ara, Francesca; Rigamonti, Claudia; Suttora, Chiara; Zanchi, Paola; Salerni, Nicoletta; Lalatta, Faustina; Vizziello, Paola

    2018-01-01

    Background: Children with sex chromosome trisomies (SCT) frequently show problems in language development. However, a clear description of the communicative patterns of these children is still lacking. Aims: To describe the first stages of language development in children with SCT in comparison with those in typically developing (TD) children. The…

  7. Young friendship in HFASD and typical development: friend versus non-friend comparisons.

    PubMed

    Bauminger-Zviely, Nirit; Agam-Ben-Artzi, Galit

    2014-07-01

    This study conducted comparative assessment of friendship in preschoolers with high-functioning autism spectrum disorder (HFASD, n = 29) versus preschoolers with typical development (n = 30), focusing on interactions with friends versus acquaintances. Groups were matched on SES, verbal/nonverbal MA, IQ, and CA. Multidimensional assessments included: mothers' and teachers' reports about friends' and friendship characteristics and observed individual and dyadic behaviors throughout interactions with friends versus non-friends during construction, drawing, and free-play situations. Findings revealed group differences in peer interaction favoring the typical development group, thus supporting the neuropsychological profile of HFASD. However, both groups' interactions with friends surpassed interactions with acquaintances on several key socio-communicative and intersubjective capabilities, thus suggesting that friendship may contribute to enhancement and practice of social interaction in HFASD.

  8. Early Numeracy in Cerebral Palsy: Review and Future Research

    ERIC Educational Resources Information Center

    van Rooijen, Maaike; Verhoeven, Ludo; Steenbergen, Bert

    2011-01-01

    Children with cerebral palsy (CP) often have problems with arithmetic, but the development of numerical abilities in these children has received only minor attention. In comparison, detailed accounts have been written on the arithmetic abilities of typically developing children, but a theoretical framework is still lacking. A promising perspective…

  9. Infant Development in Fragile X Syndrome: Cross-Syndrome Comparisons

    ERIC Educational Resources Information Center

    Roberts, Jane E.; McCary, Lindsay M.; Shinkareva, Svetlana V.; Bailey, Donald B., Jr.

    2016-01-01

    This study examined the developmental profile of male infants with fragile X syndrome (FXS) and its divergence from typical development and development of infants at high risk for autism associated with familial recurrence (ASIBs). Participants included 174 boys ranging in age from 5 to 28 months. Cross-sectional profiles on the Mullen Scales of…

  10. Play preference of children with ADHD and typically developing children in Brazil: a pilot study.

    PubMed

    Pfeifer, Luzia Iara; Terra, Lauana Nogueira; dos Santos, Jair Lício Ferreira; Stagnitti, Karen Ellen; Panúncio-Pinto, Maria Paula

    2011-12-01

    Children with attention deficit hyperactivity disorder (ADHD) have been reported to have play deficits, which can cause problems in occupational development. The aim of this paper was to report research findings on children with ADHD and typically developing children in relation to preference of play partners, play places, toys and type of play. Thirty-two school aged children from low socioeconomic status were divided into two groups. One group of 16 children with ADHD were matched with 16 typically developing children. There were no significant differences between the two groups in relation to play partners, with classmates being the most frequent play partner for both groups. There were significant differences between the two groups in preferred place to play. Children with ADHD preferred to play in school and typically developing children preferred to play on the street. There were significant differences in relation to toys and type of play engaged in with children with ADHD preferring educational materials and typically developing children preferring electronic games. These findings add to knowledge of Brazilian children with ADHD and their play preferences. Comparisons are made with research with Australian children with and without ADHD. © 2011 The Authors. Australian Occupational Therapy Journal © 2011 Occupational Therapy Australia.

  11. Comparison of Scores on the Checklist for Autism Spectrum Disorder, Childhood Autism Rating Scale, and Gilliam Asperger's Disorder Scale for Children with Low Functioning Autism, High Functioning Autism, Asperger's Disorder, ADHD, and Typical Development

    ERIC Educational Resources Information Center

    Mayes, Susan Dickerson; Calhoun, Susan L.; Murray, Michael J.; Morrow, Jill D.; Yurich, Kirsten K. L.; Mahr, Fauzia; Cothren, Shiyoko; Purichia, Heather; Bouder, James N.; Petersen, Christopher

    2009-01-01

    Reliability and validity for three autism instruments were compared for 190 children with low functioning autism (LFA), 190 children with high functioning autism or Asperger's disorder (HFA), 76 children with attention deficit hyperactivity disorder (ADHD), and 64 typical children. The instruments were the Checklist for Autism Spectrum Disorder…

  12. The capacity to adapt to changing balance threats: a comparison of children with cerebral palsy and typically developing children.

    PubMed

    Burtner, P A; Woollacott, M H; Craft, G L; Roncesvalles, M N

    2007-01-01

    This study investigated differences in reactive balance abilities of typically developing children and those with spastic diplegia. Recovery from balance threats was compared by: (i) Platform velocity and amplitude thresholds: Speed and size of platform movement at which children required assistance to remain upright, (ii) percentage of trials with feet-in-place vs. loss of balance, and (iii) center of pressure measures. Participants included 8 children with spastic diplegic cerebral palsy, 15 developmentally matched children (similar walking stages) and 21 age-matched control children. Backward platform movements graded as easy, moderate and difficult were unexpectedly imposed on children standing on a moveable platform. Children with cerebral palsy (CP) had lower platform velocity thresholds, greater percentages of loss of balance trials, increased distances and increased frequency of directional changes in center-of-pressure (COP) trajectories than control children. Older children with CP fell more often than those under 5 years. Greatest differences between children with and without CP were found in comparisons based on age rather than developmental levels. Using balance perturbations that challenged children with CP to the limits of their balance abilities effectively identified age performance differences and differences compared to typically developing children. Implications for rehabilitation programs are presented.

  13. Variation of cleavage pattern permitting normal development in a sand dollar, Peronella japonica: comparison with other sand dollars.

    PubMed

    Amemiya, S; Arakawa, E

    1996-09-01

    Peronella japonica, a sand dollar, forms an abbreviated pluteus larva and metamorphoses within 3 days without feeding. In the present study, the cleavage pattern of Peronella embryos was found to be quite irregular in the vegetal blastomeres at the fourth cleavage. Less than half of the embryos examined formed four typical micromeres. The majority formed zero, one, two or three typical micromeres of regular size, and the blastomere(s) remaining in the vegetal-most region was atypical in size and/or its direction of division. Most embryos were able to form pluteus larvae and a considerable proportion of these metamorphosed into juvenile sea urchins, regardless of whether or not they had formed four typical micromeres of regular size, although embryos which formed no typical micromeres developed into pluteus larvae less frequently. The micromere progeny in Peronella embryos form skeletogenic mesenchyme cells. The average numbers of skeletogenic mesenchyme cells in the three sand dollar species, Clypeaster japonicus, Astriclypeus manni and P. japonica were 62, 122 and 219, respectively. In these species, the skeletogenic mesenchyme cell-specific glycoprotein (msp130) was first detected immediately after ingression of the primary mesenchyme cells, spicules appeared at the early gastrula stage and triradiate spicules were found in late gastrulae. Appearance of these characteristics was markedly accelerated in the embryos of A. manni and P. japonica in comparison with those of C. japonicus. Each step in the formation of larval spicules was equally accelerated in A. manni and P. japonica, although the appearance of the adult skeleton was further accelerated in P. japonica in comparison with A. manni, possibly because of omission of the four- to eight-armed pluteus stages.

  14. Behavioural Patterns of Conflict Resolution Strategies in Preschool Boys with Language Impairment in Comparison with Boys with Typical Language Development

    ERIC Educational Resources Information Center

    Horowitz, Laura; Jansson, Liselotte; Ljungberg, Tomas; Hedenbro, Monica

    2005-01-01

    Background: Children with language impairment (LI) experience social difficulties, including conflict management. This paper is therefore motivated to examine behavioural processes guiding preschool peer conflict progression, which ultimately contributes to overall development. Aims: To describe behavioural sequences in conflicts between children…

  15. The Behaviors of Parents of Children with Autism Predict the Subsequent Development of Their Children's Communication.

    ERIC Educational Resources Information Center

    Siller, Michael; Sigman, Marian

    2002-01-01

    Comparison of caregiver behaviors of children with either autism, developmental delay, or typical development found no difference between groups in caregiver synchronization with the child's focus of attention. Also, caregivers of children with autism who showed higher levels of synchronization during initial play interactions led to superior…

  16. Using Robot Animation to Promote Gestural Skills in Children with Autism Spectrum Disorders

    ERIC Educational Resources Information Center

    So, W.-C.; Wong, M. K.-Y.; Cabibihan, J.-J.; Lam, C. K.-Y.; Chan, R. Y.-Y.; Qian, H.-H.

    2016-01-01

    School-aged children with autism spectrum disorders (ASDs) have delayed gestural development, in comparison with age-matched typically developing children. In this study, an intervention program taught children with low-functioning ASD gestural comprehension and production using video modelling (VM) by a computer-generated robot animation. Six to…

  17. Pretend play, deferred imitation and parent-child interaction in speaking and non-speaking children with autism.

    PubMed

    Strid, Karin; Heimann, Mikael; Tjus, Tomas

    2013-02-01

    This study investigates spontaneous pretend play during a parent-child free play observation, and deferred imitation observed in an experimental setting in speaking and non-speaking children with autism in comparison to children with typical development. Both groups of children with autism showed a reduced level of deferred imitation compared to the typically developing group, but only the non-speaking children with autism spent significantly less time in pretend play compared to children with typical development. Deferred imitation was related to parents' verbal interaction in both groups. An analysis of the parent-child interaction revealed that parents of children with autism used less synchronized comments compared to parents of typically developing children. Parents of the speaking group with autism used more synchronized than unsynchronized comments, while parents of the non-speaking group used the same amount of synchronized and unsynchronized comments. These findings are discussed in terms of how the developmental level affects behavior and interaction in autism. © 2012 The Authors. Scandinavian Journal of Psychology © 2012 The Scandinavian Psychological Associations.

  18. Indicators of Theory of Mind in Narrative Production: A Comparison between Individuals with Genetic Syndromes and Typically Developing Children

    ERIC Educational Resources Information Center

    Lorusso, M. L.; Galli, R.; Libera, L.; Gagliardi, C.; Borgatti, R.; Hollebrandse, B.

    2007-01-01

    It is a matter of debate whether the development of theory of mind (ToM) depends on linguistic development or is, rather, an expression of cognitive development. The study of genetic syndromes, which are characterized by intellectual impairment as well as by different linguistic profiles, may provide useful information with respect to this issue.…

  19. Children's Development of Intonation during the First Year of Cochlear Implant Experience

    ERIC Educational Resources Information Center

    Snow, David P.; Ertmer, David J.

    2012-01-01

    This article describes the longitudinal development of intonation in 18 deaf children who received cochlear implants (CIs) before the age of 3 years and 12 infants with typical development (TD) who served as controls. At the time their implants were activated, the children with CIs ranged in age from 9 to 36 months. Cross-group comparisons were…

  20. The mind behind the message: advancing theory-of-mind scales for typically developing children, and those with deafness, autism, or Asperger syndrome.

    PubMed

    Peterson, Candida C; Wellman, Henry M; Slaughter, Virginia

    2012-01-01

    Children aged 3-12 years (n = 184) with typical development, deafness, autism, or Asperger syndrome took a series of theory-of-mind (ToM) tasks to confirm and extend previous developmental scaling evidence. A new sarcasm task, in the format of H. M. Wellman and D. Liu's (2004) 5-step ToM Scale, added a statistically reliable 6th step to the scale for all diagnostic groups. A key previous finding, divergence in task sequencing for children with autism, was confirmed. Comparisons among diagnostic groups, controlling age, and language ability, showed that typical developers mastered the 6 ToM steps ahead of each of the 3 disabled groups, with implications for ToM theories. The final (sarcasm) task challenged even nondisabled 9-year-olds, demonstrating the new scale's sensitivity to post-preschool ToM growth. © 2012 The Authors. Child Development © 2012 Society for Research in Child Development, Inc.

  1. The mind behind the message: Advancing theory of mind scales for typically developing children, and those with deafness, autism, or Asperger Syndrome

    PubMed Central

    Peterson, Candida C.; Wellman, Henry M.; Slaughter, Virginia

    2013-01-01

    Children aged 3 to 12 years (n=184) with typical development, deafness, autism or Asperger Syndrome took a series of theory-of-mind (ToM) tasks to confirm and extend previous developmental scaling evidence. A new sarcasm task, in the format of Wellman and Liu’s (2004) 5-step ToM scale, added a statistically reliable sixth step to the scale for all diagnostic groups. A key previous finding, divergence in task sequencing for children with autism, was confirmed. Comparisons among diagnostic groups, controlling age and language ability, showed that typical developers mastered the six ToM steps ahead of each of the three disabled groups, with implications for ToM theories. The final (sarcasm) task challenged even nondisabled 9-year-olds, demonstrating the new scale’s sensitivity to post-preschool ToM growth. PMID:22304467

  2. Predicting Receptive-Expressive Vocabulary Discrepancies in Preschool Children With Autism Spectrum Disorder.

    PubMed

    McDaniel, Jena; Yoder, Paul; Woynaroski, Tiffany; Watson, Linda R

    2018-05-15

    Correlates of receptive-expressive vocabulary size discrepancies may provide insights into why language development in children with autism spectrum disorder (ASD) deviates from typical language development and ultimately improve intervention outcomes. We indexed receptive-expressive vocabulary size discrepancies of 65 initially preverbal children with ASD (20-48 months) to a comparison sample from the MacArthur-Bates Communicative Development Inventories Wordbank (Frank, Braginsky, Yurovsky, & Marchman, 2017) to quantify typicality. We then tested whether attention toward a speaker and oral motor performance predict typicality of the discrepancy 8 months later. Attention toward a speaker correlated positively with receptive-expressive vocabulary size discrepancy typicality. Imitative and nonimitative oral motor performance were not significant predictors of vocabulary size discrepancy typicality. Secondary analyses indicated that midpoint receptive vocabulary size mediated the association between initial attention toward a speaker and end point receptive-expressive vocabulary size discrepancy typicality. Findings support the hypothesis that variation in attention toward a speaker might partially explain receptive-expressive vocabulary size discrepancy magnitude in children with ASD. Results are consistent with an input-processing deficit explanation of language impairment in this clinical population. Future studies should test whether attention toward a speaker is malleable and causally related to receptive-expressive discrepancies in children with ASD.

  3. Hebrew Language Assessment Measure for Preschool Children: A Comparison between Typically Developing Children and Children with Specific Language Impairment

    ERIC Educational Resources Information Center

    Katzenberger, Irit; Meilijson, Sara

    2014-01-01

    The Katzenberger Hebrew Language Assessment for Preschool Children (henceforth: the KHLA) is the first comprehensive, standardized language assessment tool developed in Hebrew specifically for older preschoolers (4;0-5;11 years). The KHLA is a norm-referenced, Hebrew specific assessment, based on well-established psycholinguistic principles, as…

  4. Ultra-Rapid Categorization of Meaningful Real-Life Scenes in Adults with and without ASD

    ERIC Educational Resources Information Center

    Vanmarcke, Steven; Van Der Hallen, Ruth; Evers, Kris; Noens, Ilse; Steyaert, Jean; Wagemans, Johan

    2016-01-01

    In comparison to typically developing (TD) individuals, people with autism spectrum disorder (ASD) appear to be worse in the fast extraction of the global meaning of a situation or picture. Ultra-rapid categorization [paradigm developed by Thorpe et al. ("Nature" 381:520-522, 1996)] involves such global information processing. We…

  5. Motivational Differences among Students with ADHD Reading Disabilities, Combined Groups, and Typical Comparisons

    ERIC Educational Resources Information Center

    Lee, Jiyeon

    2010-01-01

    The purpose of this study was to assess reading motivational differences of students with reading disabilities/difficulties (RD), attention deficit hyperactive disorders/at-risk for ADHD, combined groups (RD+ADHD), and non-disabled comparisons (ND). Most motivational research has made academic motivational comparisons with typical students without…

  6. Understanding less than nothing: children's neural response to negative numbers shifts across age and accuracy.

    PubMed

    Gullick, Margaret M; Wolford, George

    2013-01-01

    We examined the brain activity underlying the development of our understanding of negative numbers, which are amounts lacking direct physical counterparts. Children performed a paired comparison task with positive and negative numbers during an fMRI session. As previously shown in adults, both pre-instruction fifth-graders and post-instruction seventh-graders demonstrated typical behavioral and neural distance effects to negative numbers, where response times and parietal and frontal activity increased as comparison distance decreased. We then determined the factors impacting the distance effect in each age group. Behaviorally, the fifth-grader distance effect for negatives was significantly predicted only by positive comparison accuracy, indicating that children who were generally better at working with numbers were better at comparing negatives. In seventh-graders, negative number comparison accuracy significantly predicted their negative number distance effect, indicating that children who were better at working with negative numbers demonstrated a more typical distance effect. Across children, as age increased, the negative number distance effect increased in the bilateral IPS and decreased frontally, indicating a frontoparietal shift consistent with previous numerical development literature. In contrast, as negative comparison task accuracy increased, the parietal distance effect increased in the left IPS and decreased in the right, possibly indicating a change from an approximate understanding of negatives' values to a more exact, precise representation (particularly supported by the left IPS) with increasing expertise. These shifts separately indicate the effects of increasing maturity generally in numeric processing and specifically in negative number understanding.

  7. Mesial Temporal Lobe and Memory Function in Autism Spectrum Disorder: An Exploration of Volumetric Findings

    PubMed Central

    Trontel, Haley G.; Duffield, Tyler C.; Bigler, Erin D.; Abildskov, Tracy J.; Froehlich, Alyson; Prigge, Molly B.D.; Travers, Brittany G.; Anderson, Jeffrey S.; Zielinski, Brandon A.; Alexander, Andrew; Lange, Nicholas; Lainhart, Janet E.

    2015-01-01

    Studies have shown that individuals with autism spectrum disorder (ASD) tend to perform significantly below typical developing individuals on standardized measures of memory, even when not significantly different on measures of IQ. The current study sought to examine within ASD whether anatomical correlates of memory performance differed between those with average-to-above-average IQ (AIQ Group) compared to those with low average to borderline ability (LIQ group) as well as in relations to typically-developing comparisons (TDC). Using automated volumetric analyses, we examined regional volume of classic memory areas including the hippocampus, parahippocampal gyrus, entorhinal cortex, and amygdala in an all-male sample AIQ (n = 38) and LIQ (n = 18) individuals with ASD along with 30 typically-developing comparisons (TDC). Memory performance was assessed using the Test of Memory and Learning (TOMAL) compared among the groups and then correlated with regional brain volumes. Analyses revealed group differences on almost all facets of memory and learning as assessed by the various subtests of the TOMAL. The three groups did not differ on any ROI memory-related brain volumes. However, significant size-memory function interactions were observed. Negative correlations were found between the volume of the amygdala and composite, verbal, and delayed memory indices for the LIQ ASD group indicating larger volume related to poorer performance. Implications for general memory functioning and dysfunctional neural connectivity in ASD are discussed. PMID:25749302

  8. Imaging decision about whether to benefit self by harming others: Adolescents with conduct and substance problems, with or without callous-unemotionality, or developing typically.

    PubMed

    Sakai, Joseph T; Dalwani, Manish S; Mikulich-Gilbertson, Susan K; Raymond, Kristen; McWilliams, Shannon; Tanabe, Jody; Rojas, Don; Regner, Michael; Banich, Marie T; Crowley, Thomas J

    2017-05-30

    We sought to identify brain activation differences in conduct-problem youth with limited prosocial emotions (LPE) compared to conduct-problem youth without LPE and community adolescents, and to test associations between brain activation and severity of callous-unemotional traits. We utilized a novel task, which asks subjects to repeatedly decide whether to accept offers where they will benefit but a beneficent other will be harmed. Behavior on this task has been previously associated with levels of prosocial emotions and severity of callous-unemotional traits, and is related to empathic concern. During fMRI acquisition, 66 male adolescents (21 conduct-problem patients with LPE, 21 without, and 24 typically-developing controls) played this novel game. Within typically-developing controls, we identified a network engaged during decision involving bilateral insula, and inferior parietal and medial frontal cortices, among other regions. Group comparisons using non-parametric (distribution-free) permutation tests demonstrated LPE patients had lower activation estimates than typically-developing adolescents in right anterior insula. Additional significant group differences emerged with our a priori parametric cluster-wise inference threshold. These results suggest measurable functional brain activation differences in conduct-problem adolescents with LPE compared to typically-developing adolescents. Such differences may underscore differential treatment needs for conduct-problem males with and without LPE. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

  9. Deconstructing executive deficits among persons with autism: implications for cognitive neuroscience.

    PubMed

    Russo, Natalie; Flanagan, Tara; Iarocci, Grace; Berringer, Darlene; Zelazo, Philip David; Burack, Jacob A

    2007-10-01

    Individuals with autism demonstrate impairments on measures of executive function (EF) relative to typically developing comparison participants. EF is comprised of several processes including inhibition, working memory and set shifting that develop throughout the lifespan. Impairments in EF may appear early in development and persist, or may represent a more transient delay which resolves with time. Given the unevenness of the cognitive profile of persons with autism, understanding the development of EF poses methodological challenges. These issues include those related to matching measures and the choice of comparison participants to which the performance of persons with autism will be compared. In the current review, we attempt to break down the processes of inhibition, working memory and set shifting among persons with autism. We propose to do this within a developmental perspective that highlights how matching measures and comparison participants can affect the interpretation of research findings.

  10. Parenting a Child with ASD: Comparison of Parenting Style Between ASD, Anxiety, and Typical Development.

    PubMed

    Ventola, Pamela; Lei, Jiedi; Paisley, Courtney; Lebowitz, Eli; Silverman, Wendy

    2017-09-01

    Parenting children with ASD has a complex history. Given parents' increasingly pivotal role in children's treatment, it is critical to consider parental style and behaviours. This study (1) compares parenting style of parents of children with ASD, parents of children with anxiety disorders, and parents of typically developing (TD) children and (2) investigates contributors to parenting style within and between groups. Parents of children with anxiety had a distinct parenting style compared to ASD and TD parents. Unique relationships between child symptoms and parenting behaviours emerged across the three groups. Understanding factors that impact parenting between and within clinical groups can guide the development of interventions better tailored to support the needs of parents, particularly parents of children with ASD.

  11. Mathematical difficulties in nonverbal learning disability or co-morbid dyscalculia and dyslexia.

    PubMed

    Mammarella, Irene C; Bomba, Monica; Caviola, Sara; Broggi, Fiorenza; Neri, Francesca; Lucangeli, Daniela; Nacinovich, Renata

    2013-01-01

    The main goal of the present study was to shed further light on the weaknesses of children with different profiles of mathematical difficulties, testing children with nonverbal learning disability (NLD), co-morbid dyscalculia and dyslexia (D&D), or typical development (TD). Sixteen children with NLD, 15 with D&D, and 16 with TD completed tasks derived from Butterworth (2003 ) and divided into: a capacity subscale (i.e., a number-dots comparison task, a number comparison task, and a dots comparison task); and an achievement subscale (i.e., mental calculations and arithmetical fact retrieval). Children with NLD were impaired in the dots comparison task, children with D&D in the mental calculation and arithmetical facts.

  12. The early development of stereotypy and self-injury: a review of research methods.

    PubMed

    Symons, F J; Sperry, L A; Dropik, P L; Bodfish, J W

    2005-02-01

    The origin and developmental course of stereotypic and self-injurious behaviour among individuals with developmental disabilities such as intellectual disability (ID) or pervasive development disorders such as autism is not well understood. Twelve studies designed to document the prevalence, nature, or development of stereotypic and/or self-injurious behaviour in children under 5 years of age and identified as at risk for developmental delay or disability were reviewed. Comparisons were made with similar studies with typically developing children. It appears that the onset of naturally occurring rhythmic motor stereotypies is delayed in young at-risk children, but that the sequencing may be similar. A very small database, differences in samples, measures, and designs limited the degree to which comparisons could be made across studies. Future work is needed based on appropriately designed prospective comparison studies and uniform quantitative measures to provide an empirical basis for new knowledge about the early development of one of the most serious behaviour disorders afflicting children with ID and related problems of development.

  13. Simple View of Reading in Down's syndrome: the role of listening comprehension and reading skills.

    PubMed

    Roch, Maja; Levorato, M Chiara

    2009-01-01

    According to the 'Simple View of Reading' (Hoover and Gough 1990), individual differences in reading comprehension are accounted for by decoding skills and listening comprehension, each of which makes a unique and specific contribution. The current research was aimed at testing the Simple View of Reading in individuals with Down's syndrome and comparing their profiles with typically developing first graders. Listening comprehension and the ability to read both words and non-words was compared in two groups with the same level of reading comprehension: 23 individuals with Down's syndrome aged between 11 years 3 months and 18 years 2 months and 23 first-grade typically developing children aged between 6 years 2 months and 7 years 4 months. The results indicate that at the same level of reading comprehension, individuals with Down's syndrome have less developed listening comprehension and more advanced word recognition than typically developing first graders. A comparison of the profiles of the two groups revealed that reading comprehension level was predicted by listening comprehension in both groups of participants and by word-reading skills only in typically developing children. The Simple View of Reading model is confirmed for individuals with Down's syndrome, although they do not show the reading profile of typically developing first graders; rather, they show an atypical profile similar to that of 'poor comprehenders' (Cain and Oakhill 2006). The crucial role of listening comprehension in Down's syndrome is also discussed with reference to the educational implications.

  14. A comparison of the function, activity and participation and quality of life between down syndrome children and typically developing children.

    PubMed

    Jung, Hee-Kyoung; Chung, EunJung; Lee, Byoung-Hee

    2017-08-01

    [Purpose] To compare function, activity, participation, and quality of life of Down syndrome children and typically developing children according to age. [Subjects and Methods] A total of 16 Down syndrome children and 20 children with typical development were included as subjects for this study. International Classification of Functioning, Disability, and Health (ICF) Child and Youth version (CY) developed by the World Health Organization (WHO) and a questionnaire were used to measure children's functioning, activity, and participation. To measure quality of life, KIDSCREEN 52-HRQOL questionnaire was used in this study. [Results] ICF-CY function, activity, participation, and quality of life showed statistically significant differences between Down syndrome children and typically developing children. Down syndrome children with higher functions showed higher activities and participation. Higher function, activity and participation features were correlated with better quality of life. Higher function resulted in better quality of life. [Conclusion] Function, activity, participation, quality of life, and several common factors of Down syndrome children depend on the ability of children. Function of Down syndrome children affects their activity, participation, and quality of life. Activities and participations also affect quality of life. Therefore, children's functional aspect is the foundation for quality of life.

  15. Parenting Children with Borderline Intellectual Functioning: A Unique Risk Population

    ERIC Educational Resources Information Center

    Fenning, Rachel M.; Baker, Jason K.; Baker, Bruce L.; Crnic, Keith A.

    2007-01-01

    Parenting was examined among families of children with borderline intelligence in comparison to families of typically developing children and children with developmental delays. Parenting data were obtained at child age 5 via naturalistic home observation. Mothers of children with borderline intelligence exhibited less positive and less sensitive…

  16. Neurodevelopmental Problems in Maltreated Children Referred with Indiscriminate Friendliness

    ERIC Educational Resources Information Center

    Kocovska, Eva; Puckering, Christine; Follan, Michael; Smillie, Maureen; Gorski, Charlotta; Barnes, James; Wilson, Philip; Young, David; Lidstone, Emma; Pritchett, Rachel; Hockaday, Harriet; Minnis, Helen

    2012-01-01

    We aimed to explore the extent of neurodevelopmental difficulties in severely maltreated adopted children. We recruited 34 adopted children, referred with symptoms of indiscriminate friendliness and a history of severe maltreatment in their early childhood and 32 typically developing comparison children without such a history, living in biological…

  17. Improving Literacy Achievement for English Learners in Transitional Bilingual Programs.

    ERIC Educational Resources Information Center

    Saunders, William M.

    1999-01-01

    Reports on the development and evaluation of a transitional bilingual program for grades 2 through 5. Evaluation results based on achievement of 42 students and 42 comparisons show that the program is more effective than the transition program students typically receive. Discusses implications for education of English learners. (SLD)

  18. Do Adolescents with Specific Language Impairment Understand Driving Terminology?

    ERIC Educational Resources Information Center

    Pandolfe, Jessica M.; Wittke, Kacie; Spaulding, Tammie J.

    2016-01-01

    Purpose: This study examined if adolescents with specific language impairment (SLI) understand driving vocabulary as well as their typically developing (TD) peers. Method: A total of 16 adolescents with SLI and 16 TD comparison adolescents completed a receptive vocabulary task focused on driving terminology derived from statewide driver's manuals.…

  19. Stability and Change in Markers of Core Numerical Competencies

    ERIC Educational Resources Information Center

    Reeve, Robert; Reynolds, Fiona; Humberstone, Judi; Butterworth, Brian

    2012-01-01

    Dot enumeration (DE) and number comparison (NC) abilities are considered markers of core number competence. Differences in DE/NC reaction time (RT) signatures are thought to distinguish between typical and atypical number development. Whether a child's DE and NC signatures change or remain stable over time, relative to other developmental…

  20. Motor Coordination in Autism Spectrum Disorders: A Synthesis and Meta-Analysis

    ERIC Educational Resources Information Center

    Fournier, Kimberly A.; Hass, Chris J.; Naik, Sagar K.; Lodha, Neha; Cauraugh, James H.

    2010-01-01

    Are motor coordination deficits an underlying cardinal feature of Autism Spectrum Disorders (ASD)? Database searches identified 83 ASD studies focused on motor coordination, arm movements, gait, or postural stability deficits. Data extraction involved between-group comparisons for ASD and typically developing controls (N = 51). Rigorous…

  1. Does theory of mind performance differ in children with early-onset and regressive autism?

    PubMed

    Matthews, Nicole L; Goldberg, Wendy A; Lukowski, Angela F; Osann, Kathryn; Abdullah, Maryam M; Ly, Agnes R; Thorsen, Kara; Spence, M Anne

    2012-01-01

    A deficit in theory of mind (ToM), or the ability to infer the mental states of others, has been implicated as one of the major characteristics of Autism Spectrum Disorder (ASD); however, little attention has been devoted to possible differences in ToM ability within ASD. The current study examined ToM performance in children with early-onset autism and regressive autism in comparison to typically developing children. Results indicated that children in the regressive autism group performed significantly better than the early-onset autism group on the non-verbal appearance-reality task. Additionally, Fisher's exact tests indicated a pattern of lowest scores in the early-onset group and highest scores in the typically developing group, whereas the regressive autism group tended to score in between the early-onset and typically developing groups. The apparent heterogeneity in ToM performance within ASD could account for the lack of universality in ToM ability found in previous studies. © 2011 Blackwell Publishing Ltd.

  2. Investigation of the mechanical behaviour of the foot skin.

    PubMed

    Fontanella, C G; Carniel, E L; Forestiero, A; Natali, A N

    2014-11-01

    The aim of this work was to provide computational tools for the characterization of the actual mechanical behaviour of foot skin, accounting for results from experimental testing and histological investigation. Such results show the typical features of skin mechanics, such as anisotropic configuration, almost incompressible behaviour, material and geometrical non linearity. The anisotropic behaviour is mainly determined by the distribution of collagen fibres along specific directions, usually identified as cleavage lines. To evaluate the biomechanical response of foot skin, a refined numerical model of the foot is developed. The overall mechanical behaviour of the skin is interpreted by a fibre-reinforced hyperelastic constitutive model and the orientation of the cleavage lines is implemented by a specific procedure. Numerical analyses that interpret typical loading conditions of the foot are performed. The influence of fibres orientation and distribution on skin mechanics is outlined also by a comparison with results using an isotropic scheme. A specific constitutive formulation is provided to characterize the mechanical behaviour of foot skin. The formulation is applied within a numerical model of the foot to investigate the skin functionality during typical foot movements. Numerical analyses developed accounting for the actual anisotropic configuration of the skin show lower maximum principal stress fields than results from isotropic analyses. The developed computational models provide reliable tools for the investigation of foot tissues functionality. Furthermore, the comparison between numerical results from anisotropic and isotropic models shows the optimal configuration of foot skin. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. Description of the motor development of 3-12 month old infants with Down syndrome: the influence of the postural body position.

    PubMed

    Tudella, Eloisa; Pereira, Karina; Basso, Renata Pedrolongo; Savelsbergh, Geert J P

    2011-01-01

    The purpose of the present study was to describe the rate of motor development in infants with Down syndrome in the age range of 3-12 months and identify the difficulties both in performance and acquiring motor skills in prone, supine, sitting and standing positions. Nineteen infants with Down syndrome and 25 healthy full term typical infants were assessed using the Alberta Infant Motor Scale (AIMS) monthly from 3 to 12 months of age. The infants with Down syndrome achieved significant later the level of motor performance of the typical infants. In the supine posture, the performance was significantly lesser for the Down syndrome infants in comparison to the typical infants from the 3rd to 6th month and in the 8th month. In the prone, sitting and standing postures this difference is found for all the months. In conclusion, the sequence of motor development of the Down syndrome is the same as the typical infants. However infants with Down syndrome need more time to acquire skills, mainly antigravitational ones, among them the standing position. Copyright © 2011 Elsevier Ltd. All rights reserved.

  4. The relationship of global form and motion detection to reading fluency.

    PubMed

    Englund, Julia A; Palomares, Melanie

    2012-08-15

    Visual motion processing in typical and atypical readers has suggested aspects of reading and motion processing share a common cortical network rooted in dorsal visual areas. Few studies have examined the relationship between reading performance and visual form processing, which is mediated by ventral cortical areas. We investigated whether reading fluency correlates with coherent motion detection thresholds in typically developing children using random dot kinematograms. As a comparison, we also evaluated the correlation between reading fluency and static form detection thresholds. Results show that both dorsal and ventral visual functions correlated with components of reading fluency, but that they have different developmental characteristics. Motion coherence thresholds correlated with reading rate and accuracy, which both improved with chronological age. Interestingly, when controlling for non-verbal abilities and age, reading accuracy significantly correlated with thresholds for coherent form detection but not coherent motion detection in typically developing children. Dorsal visual functions that mediate motion coherence seem to be related maturation of broad cognitive functions including non-verbal abilities and reading fluency. However, ventral visual functions that mediate form coherence seem to be specifically related to accurate reading in typically developing children. Copyright © 2012 Elsevier Ltd. All rights reserved.

  5. Analysis of typical world countries' wind power and PV industry policies and their enlightenment to China

    NASA Astrophysics Data System (ADS)

    Zeng, Ming; Yang, Lijun; Qiu, Hongji; Li, Yuanfei; Peng, Lilin

    2017-01-01

    The wind power and PV are the key fields of clean energy development in China in recent years. However, there are still many aspects of problems in wind power and PV industries at present, such as the insufficient consumptive ability and the limitation of market competition capability. The effective leading and support of government in the aspect of policies is especially needed in order to solve these problems. Based on the analysis of main policies system of wind power and PV in our country, Spain, the United Kingdom and Germany are chosen as typical countries because of their wind power and PV industries are relatively developed. Their policies of wind power and PV industries are studied respectively from five aspects, namely macroscopic laws, development planning, administrative policies, fiscal and tax policies and price policies. Then the comparison among typical countries and China is made and the exiting problems in China's policies of wind power and PV industries are summed up. Finally, the suggestions to promote China's wind power and PV industries development are presented.

  6. Effects of Sampling Context on Spontaneous Expressive Language in Males with Fragile X Syndrome or Down Syndrome

    PubMed Central

    Kover, Sara T.; McDuffie, Andrea; Abbeduto, Leonard; Brown, W. Ted

    2012-01-01

    Purpose This study examined the impact of sampling context on multiple aspects of expressive language in males with fragile X syndrome in comparison to males with Down syndrome or typical development. Method Participants with fragile X syndrome (n = 27), ages 10 to 17 years, were matched groupwise on nonverbal mental age to adolescents with Down syndrome (n = 15) and typically developing 3- to 6-year-olds (n = 15). Language sampling contexts were an interview-style conversation and narration of a wordless book, with scripted examiner behavior. Language was assessed in terms of amount of talk, MLU of communication unit (MLCU), lexical diversity, fluency, and intelligibility. Results Participants with fragile X syndrome had lower MLCU and lexical diversity than participants with typical development. Participants with Down syndrome produced yet lower MLCU. A differential effect of context among those with fragile X syndrome, Down syndrome, and typical development emerged for the number of attempts per minute, MLCU, and fluency. For participants with fragile X syndrome, autism symptom severity related to the number of utterances produced in conversation. Aspects of examiner behavior related to participant performance. Conclusions Sampling context characteristics should be considered when assessing expressive language in individuals with neurodevelopmental disabilities. PMID:22232386

  7. Typical and Atypical Dementia Family Caregivers: Systematic and Objective Comparisons

    ERIC Educational Resources Information Center

    Nichols, Linda O.; Martindale-Adams, Jennifer; Burns, Robert; Graney, Marshall J.; Zuber, Jeffrey

    2011-01-01

    This systematic, objective comparison of typical (spouse, children) and atypical (in-law, sibling, nephew/niece, grandchild) dementia family caregivers examined demographic, caregiving and clinical variables. Analysis was of 1,476 caregivers, of whom 125 were atypical, from the Resources for Enhancing Alzheimer's Caregivers Health (REACH I and II)…

  8. [Voxel-Based Morphometry in Autism Spectrum Disorder].

    PubMed

    Yamasue, Hidenori

    2017-05-01

    Autism spectrum disorder shows deficits in social communication and interaction including nonverbal communicative behaviors (e.g., eye contact, gestures, voice prosody, and facial expressions) and restricted and repetitive behaviors as its core symptoms. These core symptoms are emerged as an atypical behavioral development in toddlers with the disorder. Atypical neural development is considered to be a neural underpinning of such behaviorally atypical development. A number of studies using voxel-based morphometry have already been conducted to compare regional brain volumes between individuals with autism spectrum disorder and those with typical development. Furthermore, more than ten papers employing meta-analyses of the comparisons using voxel based morphometry between individuals with autism spectrum disorder and those with typical development have already been published. The current review paper adds some brief discussions about potential factors contributing to the inconsistency observed in the previous findings such as difficulty in controlling the confounding effects of different developmental phases among study participants.

  9. Fundamental movement skills and autism spectrum disorders.

    PubMed

    Staples, Kerri L; Reid, Greg

    2010-02-01

    Delays and deficits may both contribute to atypical development of movement skills by children with ASD. Fundamental movement skills of 25 children with autism spectrum disorders (ASD) (ages 9-12 years) were compared to three typically developing groups using the Test of Gross Motor Development (TGMD-2). The group matched on chronological age performed significantly better on the TGMD-2. Another comparison group matched on movement skill demonstrated children with ASD perform similarly to children approximately half their age. Comparisons to a third group matched on mental age equivalence revealed the movement skills of children with ASD are more impaired than would be expected given their cognitive level. Collectively, these results suggest the movement skills of children with ASD reflect deficits in addition to delays.

  10. When Less Is More: Poor Discrimination but Good Colour Memory in Autism

    ERIC Educational Resources Information Center

    Heaton, Pamela; Ludlow, Amanda; Roberson, Debi

    2008-01-01

    In two experiments children with autism and two groups of controls matched for either chronological or non-verbal mental age were tested on tasks of colour discrimination and memory. The results from experiment 1 showed significantly poorer colour discrimination in children with autism in comparison to typically developing chronological age…

  11. Bed Prism Spectacles

    ERIC Educational Resources Information Center

    Ribeiro, Jair Lúcio Prados

    2018-01-01

    We only became aware of the existence of bed prism spectacles when a student brought them to the classroom and asked us about how they work. The device proved to be a fertile source of curiosity among the students, and, to be properly understood, it required us to develop a comparison between reflection in a typical mirror and total internal…

  12. A Profile of Interpersonal Conflict Resolution of Children with Learning Disabilities

    ERIC Educational Resources Information Center

    Agaliotis, Ioannis; Goudiras, Dimitrios

    2004-01-01

    This study involved a comparison between 30 children with Learning Disabilities (LD) and 30 typically developing peers, regarding their ability to resolve interpersonal conflict problems. It was hypothesized that the groups would show significant differences along the following parameters: (a) understanding of the components of the problems; (b)…

  13. Depression Symptoms in Boys with Autism Spectrum Disorder and Comparison Samples

    ERIC Educational Resources Information Center

    Gadow, Kenneth D.; Guttmann-Steinmetz, Sarit; Rieffe, Carolien; DeVincent, Carla J.

    2012-01-01

    This study compares severity of specific depression symptoms in boys with autism spectrum disorder (ASD), attention-deficit hyperactivity disorder (ADHD), or chronic multiple tic disorder (CMTD) and typically developing boys (Controls). Children were evaluated with parent and teacher versions of the Child Symptom Inventory-4 (CSI-4) and a…

  14. Memory Skills of Boys with Fragile X Syndrome

    ERIC Educational Resources Information Center

    Ornstein, Peter A.; Schaaf, Jennifer M.; Hooper, Stephen R.; Hatton, Deborah D.; Mirrett, Penny; Bailey, Donald B., Jr.

    2008-01-01

    Multiple aspects of memory were examined in 42 boys with fragile X syndrome and a comparison group of 42 typically developing boys matched on MA. Working memory, incidental memory, and deliberate memory were assessed with a battery that included both free-recall and recognition tasks. Findings indicated that boys with fragile X syndrome performed…

  15. Functional Magnetic Resonance Imaging of Cognitive Processing in Young Adults with Down Syndrome

    ERIC Educational Resources Information Center

    Jacola, Lisa M.; Byars, Anna W.; Chalfonte-Evans, Melinda; Schmithorst, Vincent J.; Hickey, Fran; Patterson, Bonnie; Hotze, Stephanie; Vannest, Jennifer; Chiu, Chung-Yiu; Holland, Scott K.; Schapiro, Mark B.

    2011-01-01

    The authors used functional magnetic resonance imaging (fMRI) to investigate neural activation during a semantic-classification/object-recognition task in 13 persons with Down syndrome and 12 typically developing control participants (age range = 12-26 years). A comparison between groups suggested atypical patterns of brain activation for the…

  16. Maternal Stress in Nonverbal Learning Disorder: A Comparison with Reading Disorder

    ERIC Educational Resources Information Center

    Antshel, Kevin M.; Joseph, Guy-Ronald

    2006-01-01

    Maternal stress was assessed in mothers of children ages 8 to 11 years with learning disorders (LD). Age-, gender-, and IQ-matched children with reading disorders (RD; n = 31), children with nonverbal learning disorders (NVLD; n = 21), and typically developing control participants (n = 23) participated. Mothers of children with LD reported higher…

  17. Cognitive Control and Attentional Selection in Adolescents with ADHD versus ADD

    ERIC Educational Resources Information Center

    Carr, Laurie; Henderson, John; Nigg, Joel T.

    2010-01-01

    An important research question is whether Attention Deficit Hyperactivity Disorder (ADHD) is related to early- or late-stage attentional control mechanisms and whether this differentiates a nonhyperactive subtype (ADD). This question was addressed in a sample of 145 ADD/ADHD and typically developing comparison adolescents (aged 13-17). Attentional…

  18. Brain Mechanisms for Processing Direct and Averted Gaze in Individuals with Autism

    ERIC Educational Resources Information Center

    Pitskel, Naomi B.; Bolling, Danielle Z.; Hudac, Caitlin M.; Lantz, Stephen D.; Minshew, Nancy J.; Vander Wyk, Brent C.; Pelphrey, Kevin A.

    2011-01-01

    Prior studies have indicated brain abnormalities underlying social processing in autism, but no fMRI study has specifically addressed the differential processing of direct and averted gaze, a critical social cue. Fifteen adolescents and adults with autism and 14 typically developing comparison participants viewed dynamic virtual-reality videos…

  19. Building a University Brand from within: A Comparison of Coaches' Perspectives of Internal Branding

    ERIC Educational Resources Information Center

    Judson, Kimberly M.; Gorchels, Linda; Aurand, Timothy W.

    2006-01-01

    Branding efforts have typically focused on external promotional strategies to develop brand image. Recently, the brand messages conveyed to employees of an organization have been recognized as being equally as important as the brand messages sent to external stakeholders. This study investigates the internal communication of the university brand…

  20. Brief Report: Face-Specific Recognition Deficits in Young Children with Autism Spectrum Disorders

    ERIC Educational Resources Information Center

    Bradshaw, Jessica; Shic, Frederick; Chawarska, Katarzyna

    2011-01-01

    This study used eyetracking to investigate the ability of young children with autism spectrum disorders (ASD) to recognize social (faces) and nonsocial (simple objects and complex block patterns) stimuli using the visual paired comparison (VPC) paradigm. Typically developing (TD) children showed evidence for recognition of faces and simple…

  1. The Use of Syntactic Cues in Lexical Acquisition by Children with SLI.

    ERIC Educational Resources Information Center

    Rice, Mabel L.; Cleave, Patricia L.; Oetting, Janna B.

    2000-01-01

    Two studies investigated the syntactic bootstrapping abilities of 5- and 7-year-old children with specific language impairment and comparison groups matched for equivalent language level or chronological age. Only typically developing 5-year-olds showed evidence of using syntactic clues. However, continued syntactic growth was seen in all…

  2. Reinforcement Enhances Vigilance Among Children With ADHD: Comparisons to Typically Developing Children and to the Effects of Methylphenidate

    PubMed Central

    Bubnik, Michelle G.; Hawk, Larry W.; Pelham, William E.; Waxmonsky, James G.; Rosch, Keri S.

    2014-01-01

    Sustained attention and reinforcement are posited as causal mechanisms in Attention-Deficit/Hyperactivity Disorder (ADHD), but their interaction has received little empirical study. In two studies, we examined the impact of performance-based reinforcement on sustained attention over time, or vigilance, among 9- to 12-year-old children. Study 1 demonstrated the expected vigilance deficit among children with ADHD (n=25; 12% female) compared to typically developing (TD) controls (n=33; 22% female) on a standard continuous performance task (CPT). During a subsequent visit, reinforcement improved attention more among children with ADHD than controls. Study 2 examined the separate and combined effects of reinforcement and acute methylphenidate (MPH) on CPT performance in children with ADHD (n=19; 21% female). Both reinforcement and MPH enhanced overall target detection and attenuated the vigilance decrement that occurred in no-reinforcement, placebo condition. Cross-study comparisons suggested that the combination of MPH and reinforcement eliminated the vigilance deficit in children with ADHD, normalizing sustained attention. This work highlights the clinically and theoretically interesting intersection of reinforcement and sustained attention. PMID:24931776

  3. Mathematical difficulties in developmental coordination disorder: Symbolic and nonsymbolic number processing.

    PubMed

    Gomez, Alice; Piazza, Manuela; Jobert, Antoinette; Dehaene-Lambertz, Ghislaine; Dehaene, Stanislas; Huron, Caroline

    2015-01-01

    At school, children with Developmental Coordination Disorder (DCD) struggle with mathematics. However, little attention has been paid to their numerical cognition abilities. The goal of this study was to better understand the cognitive basis for mathematical difficulties in children with DCD. Twenty 7-to-10 years-old children with DCD were compared to twenty age-matched typically developing children using dot and digit comparison tasks to assess symbolic and nonsymbolic number processing and in a task of single digits additions. Results showed that children with DCD had lower performance in nonsymbolic and symbolic number comparison tasks than typically developing children. They were also slower to solve simple addition problems. Moreover, correlational analyses showed that children with DCD who experienced greater impairments in the nonsymbolic task also performed more poorly in the symbolic tasks. These findings suggest that DCD impairs both nonsymbolic and symbolic number processing. A systematic assessment of numerical cognition in children with DCD could provide a more comprehensive picture of their deficits and help in proposing specific remediation. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Connecting the Dots between Schizotypal Symptoms and Social Anxiety in Youth with an Extra X Chromosome: A Mediating Role for Catastrophizing

    PubMed Central

    Ziermans, Tim; van Rijn, Sophie

    2017-01-01

    Youth with an extra X chromosome (47, XXY & 47, XXX) display higher levels of schizotypal symptoms and social anxiety as compared to typically developing youth. It is likely that the extra X chromosome group is at-risk for clinical levels of schizotypy and social anxiety. Hence, this study investigated how schizotypal and social anxiety symptoms are related and mechanisms that may explain their association in a group of 38 children and adolescents with an extra X chromosome and a comparison group of 109 typically developing peers (8–19 years). Three cognitive coping strategies were investigated as potential mediators, rumination, catastrophizing, and other-blame. Moderated mediation analyses revealed that the relationship between schizotypal symptoms and social anxiety was mediated by catastrophizing coping in the extra X chromosome group but not in the comparison group. The results suggest that youth with an extra X chromosome with schizotypal symptoms could benefit from an intervention to weaken the tendency to catastrophize life events as a way of reducing the likelihood of social anxiety symptoms. PMID:28878159

  5. Development of numerical processing in children with typical and dyscalculic arithmetic skills—a longitudinal study

    PubMed Central

    Landerl, Karin

    2013-01-01

    Numerical processing has been demonstrated to be closely associated with arithmetic skills, however, our knowledge on the development of the relevant cognitive mechanisms is limited. The present longitudinal study investigated the developmental trajectories of numerical processing in 42 children with age-adequate arithmetic development and 41 children with dyscalculia over a 2-year period from beginning of Grade 2, when children were 7; 6 years old, to beginning of Grade 4. A battery of numerical processing tasks (dot enumeration, non-symbolic and symbolic comparison of one- and two-digit numbers, physical comparison, number line estimation) was given five times during the study (beginning and middle of each school year). Efficiency of numerical processing was a very good indicator of development in numerical processing while within-task effects remained largely constant and showed low long-term stability before middle of Grade 3. Children with dyscalculia showed less efficient numerical processing reflected in specifically prolonged response times. Importantly, they showed consistently larger slopes for dot enumeration in the subitizing range, an untypically large compatibility effect when processing two-digit numbers, and they were consistently less accurate in placing numbers on a number line. Thus, we were able to identify parameters that can be used in future research to characterize numerical processing in typical and dyscalculic development. These parameters can also be helpful for identification of children who struggle in their numerical development. PMID:23898310

  6. Comparison with the Typical College Student Predicts Graduation When Identity Is Uncertain

    ERIC Educational Resources Information Center

    Lane, David J.

    2017-01-01

    This study investigated the effect of personal identity and social comparison on college graduation. First-year college students completed an online survey measuring exploration and commitment to personal identity and perceptions of the prototypical student. Those who perceived the typical student as favorable but dissimilar to themselves had the…

  7. Decadal water quality variations at three typical basins of Mekong, Murray and Yukon

    NASA Astrophysics Data System (ADS)

    Khan, Afed U.; Jiang, Jiping; Wang, Peng

    2018-02-01

    Decadal distribution of water quality parameters is essential for surface water management. Decadal distribution analysis was conducted to assess decadal variations in water quality parameters at three typical watersheds of Murray, Mekong and Yukon. Right distribution shifts were observed for phosphorous and nitrogen parameters at the Mekong watershed monitoring sites while left shifts were noted at the Murray and Yukon monitoring sites. Nutrients pollution increases with time at the Mekong watershed while decreases at the Murray and Yukon watershed monitoring stations. The results implied that watershed located in densely populated developing area has higher risk of water quality deterioration in comparison to thinly populated developed area. The present study suggests best management practices at watershed scale to modulate water pollution.

  8. Parenting Children With Borderline Intellectual Functioning: A Unique Risk Population

    PubMed Central

    Fenning, Rachel M.; Baker, Jason K.; Baker, Bruce L.; Crnic, Keith A.

    2009-01-01

    Parenting was examined among families of children with borderline intelligence in comparison to families of typically developing children and children with developmental delays. Parenting data were obtained at child age 5 via naturalistic home observation. Mothers of children with borderline intelligence exhibited less positive and less sensitive parenting behaviors than did other mothers and were least likely to display a style of positive engagement. Children with borderline intelligence were not observed to be more behaviorally problematic than other children; however, their mothers perceived more externalizing symptoms than did mothers of typically developing children. Findings suggest the importance of mothers’ explanatory models for child difficulties and highlight children with borderline intelligence as uniquely at risk for poor parenting. PMID:17295551

  9. Post-Buckling and Ultimate Strength Analysis of Stiffened Composite Panel Base on Progressive Damage

    NASA Astrophysics Data System (ADS)

    Zhang, Guofan; Sun, Xiasheng; Sun, Zhonglei

    Stiffened composite panel is the typical thin wall structure applied in aerospace industry, and its main failure mode is buckling subjected to compressive loading. In this paper, the development of an analysis approach using Finite Element Method on post-buckling behavior of stiffened composite structures under compression was presented. Then, the numerical results of stiffened panel are obtained by FE simulations. A thorough comparison were accomplished by comparing the load carrying capacity and key position strains of the specimen with test. The comparison indicates that the FEM results which adopted developed methodology could meet the demand of engineering application in predicting the post-buckling behavior of intact stiffened structures in aircraft design stage.

  10. 3D reconstruction software comparison for short sequences

    NASA Astrophysics Data System (ADS)

    Strupczewski, Adam; Czupryński, BłaŻej

    2014-11-01

    Large scale multiview reconstruction is recently a very popular area of research. There are many open source tools that can be downloaded and run on a personal computer. However, there are few, if any, comparisons between all the available software in terms of accuracy on small datasets that a single user can create. The typical datasets for testing of the software are archeological sites or cities, comprising thousands of images. This paper presents a comparison of currently available open source multiview reconstruction software for small datasets. It also compares the open source solutions with a simple structure from motion pipeline developed by the authors from scratch with the use of OpenCV and Eigen libraries.

  11. Artificial bias typically neglected in comparisons of uncertain atmospheric data

    NASA Astrophysics Data System (ADS)

    Pitkänen, Mikko R. A.; Mikkonen, Santtu; Lehtinen, Kari E. J.; Lipponen, Antti; Arola, Antti

    2016-09-01

    Publications in atmospheric sciences typically neglect biases caused by regression dilution (bias of the ordinary least squares line fitting) and regression to the mean (RTM) in comparisons of uncertain data. We use synthetic observations mimicking real atmospheric data to demonstrate how the biases arise from random data uncertainties of measurements, model output, or satellite retrieval products. Further, we provide examples of typical methods of data comparisons that have a tendency to pronounce the biases. The results show, that data uncertainties can significantly bias data comparisons due to regression dilution and RTM, a fact that is known in statistics but disregarded in atmospheric sciences. Thus, we argue that often these biases are widely regarded as measurement or modeling errors, for instance, while they in fact are artificial. It is essential that atmospheric and geoscience communities become aware of and consider these features in research.

  12. Developing a Mouse Model of Sensory and Cognitive Deficits for Multiple Sclerosis

    DTIC Science & Technology

    2012-07-01

    ABRs and otoacoustic emissions. More sophisticates measures, such as neural processing of binaural responses are typically performed in rats, guinea...ears we are able to calculate the binaural component of the EEGs for comparison of wild type and Claudin 11 knockout responses. We are awaiting the...knockout of the Claudin 11 gene. 2. Development of a novel anesthesia protocol to measure binaural auditory signals in the superior olivary complex of

  13. Do Spoken Nonword and Sentence Repetition Tasks Discriminate Language Impairment in Children with an ASD?

    ERIC Educational Resources Information Center

    Harper-Hill, Keely; Copland, David; Arnott, Wendy

    2013-01-01

    The primary aim of this paper was to investigate heterogeneity in language abilities of children with a confirmed diagnosis of an ASD (N = 20) and children with typical development (TD; N = 15). Group comparisons revealed no differences between ASD and TD participants on standard clinical assessments of language ability, reading ability or…

  14. A Comparison of Self-Monitoring with and without Reinforcement to Improve On-Task Classroom Behavior

    ERIC Educational Resources Information Center

    Davis, Tonya N.; Dacus, Sharon; Bankhead, Jenna; Haupert, Megan; Fuentes, Lisa; Zoch, Tamara; Kang, Soyeon; Attai, Shanna; Lang, Russell

    2014-01-01

    In this study we analyzed the effects of a self-monitoring and self-monitoring plus reinforcement intervention on classroom behavior. A typically-developing high school student demonstrating difficulty staying on-task during classroom instruction was observed in three classroom settings associated with high levels of off-task behavior. During…

  15. Comparison of the Learning Styles of Students with Autism versus Typical Elementary-School Students

    ERIC Educational Resources Information Center

    Friedlander, Diana

    2010-01-01

    Developing successful educational opportunities for students with autism has long been a challenge for educators. Although medical research is making great strides in the treatment and etiology of autism, as more and more students with autism are learning alongside their peers in the general education classroom the struggle to find effective…

  16. Learning English during the Summer: A Comparison of Two Domestic Programs for Pre-Adolescents

    ERIC Educational Resources Information Center

    Tragant, Elsa; Serrano, Raquel; Llanes, Àngels

    2017-01-01

    Contexts that promote intensive second language (L2) experiences (typically, stay abroad, immersion, etc.) are reported to facilitate language development; yet, little is known about such programs when they are addressed to school-age learners in their home country. The present study examines the experiences of learners aged 11-13 years who…

  17. Parental Stress and ASD: Relationship with Autism Symptom Severity, IQ, and Resilience

    ERIC Educational Resources Information Center

    Pastor-Cerezuela, Gemma; Fernández-Andrés, M. Inmaculada; Tárraga-Mínguez, Raúl; Navarro-Peña, J. Miguel

    2016-01-01

    The objectives of this study were (a) to evaluate parental stress in parents of children with autism spectrum disorders (ASD group) and compare it with the stress in parents of children with typical development (comparison group); (b) to study the relationship between parental stress, autism severity, and both verbal and performance IQ; and (c) to…

  18. The Handwriting Performance of Children with NF1

    ERIC Educational Resources Information Center

    Gilboa, Yafit; Josman, Naomi; Fattal-Valevski, Aviva; Toledano-Alhadef, Hagit; Rosenblum, Sara

    2010-01-01

    The objective of this study was to analyze the process and product of handwriting among children with Neurofibromatosis Type 1 (NF1) in comparison to those of Typically Developing (TD) children. Children with NF1 are at risk for some cognitive deficits, a wide range of deficits in perceptual skills and, motor and visual-motor integration skills…

  19. Lie-Telling Behavior in Children with Autism and Its Relation to False-Belief Understanding

    ERIC Educational Resources Information Center

    Talwar, Victoria; Zwaigenbaum, Lonnie; Goulden, Keith J.; Manji, Shazeen; Loomes, Carly; Rasmussen, Carmen

    2012-01-01

    Children's lie-telling behavior and its relation to false-belief understanding was examined in children with autism spectrum disorders (ASD; n = 26) and a comparison group of typically developing children (n = 27). Participants were assessed using a temptation resistance paradigm, in which children were told not to peek at a forbidden toy while…

  20. Numerical Distance Effect in Developmental Dyscalculia

    ERIC Educational Resources Information Center

    Ashkenazi, Sarit; Mark-Zigdon, Nitza; Henik, Avishai

    2009-01-01

    Children in third and fourth grades suffering from developmental dyscalculia (DD) and typically developing children were asked to compare numbers to a standard. In two separate blocks, they were asked to compare a number between 1 and 9 to 5, or a two-digit number between 10 and 99 to 55. In the single-digit comparisons, DD children were…

  1. Approximate Number Sense, Symbolic Number Processing, or Number-Space Mappings: What Underlies Mathematics Achievement?

    ERIC Educational Resources Information Center

    Sasanguie, Delphine; Gobel, Silke M.; Moll, Kristina; Smets, Karolien; Reynvoet, Bert

    2013-01-01

    In this study, the performance of typically developing 6- to 8-year-old children on an approximate number discrimination task, a symbolic comparison task, and a symbolic and nonsymbolic number line estimation task was examined. For the first time, children's performances on these basic cognitive number processing tasks were explicitly contrasted…

  2. Pragmatics Abilities in Narrative Production: A Cross-Disorder Comparison

    ERIC Educational Resources Information Center

    Norbury, Courtenay Frazier; Gemmell, Tracey; Paul, Rhea

    2014-01-01

    We aimed to disentangle contributions of socio-pragmatic and structural language deficits to narrative competence by comparing the narratives of children with autism spectrum disorder (ASD; n=25), non-autistic children with language impairments (LI; n=23), and children with typical development (TD; n=27). Groups were matched for age (6½ to 15…

  3. Comparison of Obesity, Physical Activity, and Sedentary Behaviors between Adolescents with Autism Spectrum Disorders and Without

    ERIC Educational Resources Information Center

    McCoy, Stephanie M.; Jakicic, John M.; Barone Gibbs, Bethany

    2016-01-01

    Body mass index classification, physical activity (PA), and sedentary behaviors were compared in adolescents with autism spectrum disorder (ASD) to typically developing adolescents. Participants included 42,747 adolescents (ASD, n = 915) from the 2011-2012 National Survey of Children's Health. After controlling for covariates, adolescents were…

  4. Timing Abilities among Children with Developmental Coordination Disorders (DCD) in Comparison to Children with Typical Development

    ERIC Educational Resources Information Center

    Rosenblum, Sara; Regev, Noga

    2013-01-01

    Timing ability is essential for common everyday performance. The aim of the study was to compare timing abilities and temporal aspects of handwriting performance and relationships between these two components among children with Developmental Coordination Disorders (DCD) and a control group. Forty two children, 21 diagnosed as DCD and 21 with…

  5. A Comparison of Social Skills in Turkish Children with Visual Impairments, Children with Intellectual Impairments and Typically Developing Children

    ERIC Educational Resources Information Center

    Ozkubat, Ufuk; Ozdemir, Selda

    2014-01-01

    The purpose of this study was to compare the social skills of five groups of children: children with visual impairments attending inclusive education schools, children with visual impairments attending schools for the blind, children with intellectual impairments attending inclusive education schools, children with intellectual impairments…

  6. Functional Magnetic Resonance Imaging of Story Listening in Adolescents and Young Adults with Down Syndrome: Evidence for Atypical Neurodevelopment

    ERIC Educational Resources Information Center

    Jacola, L. M.; Byars, A. W.; Hickey, F.; Vannest, J.; Holland, S. K.; Schapiro, M. B.

    2014-01-01

    Background: Previous studies have documented differences in neural activation during language processing in individuals with Down syndrome (DS) in comparison with typically developing individuals matched for chronological age. This study used functional magnetic resonance imaging (fMRI) to compare activation during language processing in young…

  7. ADHD Preschoolers with and without ODD: Do They Act Differently Depending on Degree of Task Engagement/Reward?

    ERIC Educational Resources Information Center

    Gopin, Chaya B.; Berwid, Olga; Marks, David J.; Mlodnicka, Agnieska; Halperin, Jeffrey M.

    2013-01-01

    Objective: To examine the impact of reinforcement on reaction time (RT) and RT variability (RT standard deviation [RTSD]) in preschoolers with ADHD with and without oppositional defiant disorder (ODD), and a typically developing (TD) comparison group. Method: Participants were administered a computerized task consisting of two conditions: simple…

  8. Impact of Short-Term Training in Social Cognition in Preschoolers with Externalizing Behavior

    ERIC Educational Resources Information Center

    Houssa, Marine; Jacobs, Emilie; Nader-Grosbois, Nathalie

    2017-01-01

    In two experimental and exploratory studies, we wanted to test the differentiated effects on preschoolers with externalizing behavior (EB) of two short-term social information processing (SIP) and Theory of Mind (ToM) training sessions, in comparison with typically developing (TD) preschoolers or with preschoolers with EB whom didn't receive…

  9. Comparing Service Use and Costs among Adolescents with Autism Spectrum Disorders, Special Needs and Typical Development

    ERIC Educational Resources Information Center

    Barrett, Barbara; Mosweu, Iris; Jones, Catherine R. G.; Charman, Tony; Baird, Gillian; Simonoff, Emily; Pickles, Andrew; Happé, Francesca; Byford, Sarah

    2015-01-01

    Autism spectrum disorder is a complex condition that requires specialised care. Knowledge of the costs of autism spectrum disorder, especially in comparison with other conditions, may be useful to galvanise policymakers and leverage investment in education and intervention to mitigate aspects of autism spectrum disorder that negatively impact…

  10. The role of feedback in implicit and explicit artificial grammar learning: a comparison between dyslexic and non-dyslexic adults.

    PubMed

    Schiff, Rachel; Sasson, Ayelet; Star, Galit; Kahta, Shani

    2017-10-01

    The importance of feedback for learning has been firmly established over the past few decades. The question of whether feedback plays a significant role in the statistical learning abilities of adults with dyslexia, however, is currently unresolved. Here, we examined the role of feedback in grammaticality judgment, type of structural knowledge, and confidence rating in both typically developed and dyslexic adults. We implemented two artificial grammar learning experiments: implicit and explicit. The second experiment was directly analogous to the first experiment in all respects except training format: the standard memorization instruction was replaced with an explicit rule-search instruction. Each experiment was conducted with and without performance feedback. While both groups showed significantly improved learning in the feedback-based explicit artificial grammar learning task, only the typically developed adults demonstrated higher levels of conscious structural knowledge. The present study demonstrates that the basis for the grammaticality judgment of adults with dyslexia differs from that of typically developed adults, regardless of increase in the level of explicitness.

  11. ANALYSIS OF RESPIRATORY DEPOSITION OF INHALED PARTICLES FOR DIFFERENT DOSE METRICS: COMPARISON OF NUMBER, SURFACE AREA AND MASS DOSE OF TYPICAL AMBIENT BI-MODAL AEROSOLS

    EPA Science Inventory

    ANALYSIS OF RESPIRATORY DEPOSITION OF INHALED PARTICLES FOR DIFFERENT DOSE METRICS: COMPARISON OF NUMBER, SURFACE AREA AND MASS DOSE OF TYPICAL AMBIENT BI-MODAL AEROSOLS.
    Chong S. Kim, SC. Hu*, PA Jaques*, US EPA, National Health and Environmental Effects Research Laboratory, ...

  12. An ideal-typical model for comparing interprofessional relations and skill mix in health care.

    PubMed

    Schönfelder, Walter; Nilsen, Elin Anita

    2016-11-08

    Comparisons of health system performance, including the regulations of interprofessional relations and the skill mix between health professions are challenging. National strategies for regulating interprofessional relations vary widely across European health care systems. Unambiguously defined and generally accepted performance indicators have to remain generic, with limited power for recognizing the organizational structures regulating interprofessional relations in different health systems. A coherent framework for in-depth comparisons of different models for organizing interprofessional relations and the skill mix between professional groups is currently not available. This study aims to develop an ideal-typical framework for categorizing skill mix and interprofessional relations in health care, and to assess the potential impact for different ideal types on care coordination and integrated service delivery. A document analysis of the Health Systems in Transition (HiT) reports published by the European Observatory on Health Systems and Policies was conducted. The HiT reports to 31 European health systems were analyzed using a qualitative content analysis and a process of meaning condensation. The educational tracks available to nurses have an impact on the professional autonomy for nurses, the hierarchy between professional groups, the emphasis given to negotiating skill mix, interdisciplinary teamwork and the extent of cooperation across the health and social service interface. Based on the results of the document analysis, three ideal types for regulating interprofessional relations and skill mix in health care are delimited. For each ideal type, outcomes on service coordination and holistic service delivery are described. Comparisons of interprofessional relations are necessary for proactive health human resource policies. The proposed ideal-typical framework provides the means for in-depth comparisons of interprofessional relations in the health care workforce beyond of what is possible with directly comparable, but generic performance indicators.

  13. Mind and body: concepts of human cognition, physiology and false belief in children with autism or typical development.

    PubMed

    Peterson, Candida C

    2005-08-01

    This study examined theory of mind (ToM) and concepts of human biology (eyes, heart, brain, lungs and mind) in a sample of 67 children, including 25 high functioning children with autism (age 6-13), plus age-matched and preschool comparison groups. Contrary to Baron-Cohen [1989, Journal of Autism and Developmental Disorders, 19(4), 579-600], most children with autism correctly understood the functions of the brain (84%) and the mind (64%). Their explanations were predominantly mentalistic. They outperformed typically developing preschoolers in understanding inner physiological (heart, lungs) and cognitive (brain, mind) systems, and scored as high as age-matched typical children. Yet, in line with much previous ToM research, most children with autism (60%) failed false belief, and their ToM performance was unrelated to their understanding of. human biology. Results were discussed in relation to neurobiological and social-experiential accounts of the ToM deficit in autism.

  14. Sibling self-management: Programming for generalization to improve interactions between typically developing siblings and children with autism spectrum disorders.

    PubMed

    Kryzak, Lauren A; Jones, Emily A

    2017-11-01

    The present study taught typically developing (TD) siblings of children with autism spectrum disorders (ASD) social-communicative and self-management skills. The authors' hypothesized that the acquisition of self-management skills would support generalization of targeted social-communicative responses. A multiple baseline probe design across sibling dyads was used to decrease exposure to unnecessary sessions in the absence of intervention. Four TD siblings were taught self-management of a social skills curriculum using behavioral skills training, which consisted of instructions, modeling, practice, and subsequent feedback. Results indicated that TD siblings learned to self-manage the social skills curriculum with some generalization across novel settings and over time. Comparisons of social-communicative responses to their typical peers provided some support for the social validity of the intervention outcomes. These results support the use of self-management, when explicitly programming for generalization, which continues to be a key consideration when including TD siblings in interventions with their siblings with ASD.

  15. Intra-individual cognitive imbalance in ASD between perceptual reasoning and ambiguity-solving related to tool use: Comparison among children exhibiting ASD, AD/HD, and typical development.

    PubMed

    Wakusawa, Keisuke; Nara, Chieko; Kubota, Yuki; Tomizawa, Yayoi; Taki, Yasuyuki; Sassa, Yuko; Kobayashi, Satoru; Suzuki-Muromoto, Sato; Hirose, Mieko; Yokoyama, Hiroyuki; Nara, Takahiro; Kure, Shigeo; Mori, Norio; Takei, Noriyoshi; Kawashima, Ryuta

    2018-01-01

    Several studies have suggested that objective deficits in the processing of abstract information in conjunction with an enhanced ability to process concrete information is a definitive characteristic of autism spectrum disorder (ASD). However, this cognitive imbalance is not necessarily clear in high-functioning autistic individuals who do not display absolute differences relative to typically developing (TD) populations. Thus, the purpose of this study was to identify this cognitive tendency in high-functioning autistic individuals using intra-individual cognitive comparisons. The reaction times (RTs) of TD children, children with ASD, and children with attention deficit hyperactivity disorder (AD/HD) (n=17 in each group, mean age=11.9years, age range=9.8-15.8years) were compared using the Which/How-to-Apply Tools (W/HAT) test, which consists of tasks requiring the adaptive use of novel tools and familiar tools in atypical and typical situations. Differences in RTs between the atypical and typical trials ([A-T]) were used to assess intra-individual cognitive imbalances. As predicted, the [A-T] scores of the ASD group were significantly higher than those of the TD group even though the RTs in the atypical and typical trials did not differ. Additionally, the [A-T] values were significantly higher in the ASD group than in the AD/HD group, which indicates that the cognitive imbalance was specific to ASD individuals. No significant interaction was detected between the trial and subject group. The findings of this study demonstrate that a cognitive imbalance in ASD individuals may enhance the current understanding of the pathophysiology of this disorder, which is found in a range of individuals, including those with obvious cortical dysfunction to those with only intra-individual imbalances. Copyright © 2017 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

  16. Efficient Construction of Discrete Adjoint Operators on Unstructured Grids by Using Complex Variables

    NASA Technical Reports Server (NTRS)

    Nielsen, Eric J.; Kleb, William L.

    2005-01-01

    A methodology is developed and implemented to mitigate the lengthy software development cycle typically associated with constructing a discrete adjoint solver for aerodynamic simulations. The approach is based on a complex-variable formulation that enables straightforward differentiation of complicated real-valued functions. An automated scripting process is used to create the complex-variable form of the set of discrete equations. An efficient method for assembling the residual and cost function linearizations is developed. The accuracy of the implementation is verified through comparisons with a discrete direct method as well as a previously developed handcoded discrete adjoint approach. Comparisons are also shown for a large-scale configuration to establish the computational efficiency of the present scheme. To ultimately demonstrate the power of the approach, the implementation is extended to high temperature gas flows in chemical nonequilibrium. Finally, several fruitful research and development avenues enabled by the current work are suggested.

  17. Efficient Construction of Discrete Adjoint Operators on Unstructured Grids Using Complex Variables

    NASA Technical Reports Server (NTRS)

    Nielsen, Eric J.; Kleb, William L.

    2005-01-01

    A methodology is developed and implemented to mitigate the lengthy software development cycle typically associated with constructing a discrete adjoint solver for aerodynamic simulations. The approach is based on a complex-variable formulation that enables straightforward differentiation of complicated real-valued functions. An automated scripting process is used to create the complex-variable form of the set of discrete equations. An efficient method for assembling the residual and cost function linearizations is developed. The accuracy of the implementation is verified through comparisons with a discrete direct method as well as a previously developed handcoded discrete adjoint approach. Comparisons are also shown for a large-scale configuration to establish the computational efficiency of the present scheme. To ultimately demonstrate the power of the approach, the implementation is extended to high temperature gas flows in chemical nonequilibrium. Finally, several fruitful research and development avenues enabled by the current work are suggested.

  18. Performance of the SNPforID 52 SNP-plex assay in paternity testing.

    PubMed

    Børsting, Claus; Sanchez, Juan J; Hansen, Hanna E; Hansen, Anders J; Bruun, Hanne Q; Morling, Niels

    2008-09-01

    The performance of a multiplex assay with 52 autosomal single nucleotide polymorphisms (SNPs) developed for human identification was tested on 124 mother-child-father trios. The typical paternity indices (PIs) were 10(5)-10(6) for the trios and 10(3)-10(4) for the child-father duos. Using the SNP profiles from the randomly selected trios and 700 previously typed individuals, a total of 83,096 comparisons between mother, child and an unrelated man were performed. On average, 9-10 mismatches per comparison were detected. Four mismatches were genetic inconsistencies and 5-6 mismatches were opposite homozygosities. In only two of the 83,096 comparisons did an unrelated man match perfectly to a mother-child duo, and in both cases the PI of the true father was much higher than the PI of the unrelated man. The trios were also typed for 15 short tandem repeats (STRs) and seven variable number of tandem repeats (VNTRs). The typical PIs based on 15 STRs or seven VNTRs were 5-50 times higher than the typical PIs based on 52 SNPs. Six mutations in tandem repeats were detected among the randomly selected trios. In contrast, there was not found any mutations in the SNP loci. The results showed that the 52 SNP-plex assay is a very useful alternative to currently used methods in relationship testing. The usefulness of SNP markers with low mutation rates in paternity and immigration casework is discussed.

  19. Comparison of nutritional status between children with autism spectrum disorder and typically developing children in the Mediterranean Region (Valencia, Spain).

    PubMed

    Marí-Bauset, Salvador; Llopis-González, Agustín; Zazpe, Itziar; Marí-Sanchis, Amelia; Morales Suárez-Varela, Maria

    2017-04-01

    This case-control study investigated nutrient intake, healthy eating index with 10 items on foods and nutrients, on 3-day food diaries and anthropometric measurements in 105 children with autism spectrum disorder and 495 typically developing children (6-9 years) in Valencia (Spain). Children with autism spectrum disorder were at a higher risk for underweight, eating more legumes, vegetables, fiber, and some micronutrients (traditional Mediterranean diet) but fewer dairy and cereal products, and less iodine, sodium, and calcium than their typically developing peers. Differences existed in total energy intake but healthy eating index and food variety score differences were not significant. Autism spectrum disorder group failed to meet dietary recommendations for thiamin, riboflavin, vitamin C, or calcium. Risk of inadequate intake of fiber, vitamin E, and sodium was lower in children with autism spectrum disorder than typically developing children. Results suggest that (1) risk of inadequate intake of some micronutrients in children with autism spectrum disorder and (2) cultural patterns and environment may influence food intake and anthropometric characteristics in autism spectrum disorder. Primary care should include anthropometric and nutritional surveillance in this population to identify intervention on a case-by-case basis. Future research should explore dietary patterns and anthropometric characteristics in different autism spectrum disorder populations in other countries, enhancing our understanding of the disorder's impact.

  20. Can mastication in children with cerebral palsy be analyzed by clinical observation, dynamic ultrasound and 3D kinematics?

    PubMed

    Remijn, L; Groen, B E; Speyer, R; van Limbeek, J; Vermaire, J A; van den Engel-Hoek, L; Nijhuis-van der Sanden, M W G

    2017-02-01

    The aim of this study was to explore the feasibility of the Mastication Observation and Evaluation (MOE) instrument, dynamic ultrasound and 3D kinematic measurements to describe mastication in children with spastic cerebral palsy and typically developing children. Masticatory movements during five trials of eating a biscuit were assessed in 8 children with cerebral palsy, spastic type (mean age 9.08years) and 14 typically developing children (mean age 9.01years). Differences between trials were tested (t-test) and the mastication of individual children with cerebral palsy was analyzed. MOE scores ranged from 17 to 31 (median 24) for the children with cerebral palsy and from 28 to 32 (median 31) for the typically developing children. There was an increased chewing cycle duration, a smaller left-right and up-down tongue displacement and larger anterior mandible movements for the trials (n=40) of cerebral palsy children (p<0.000 for all comparisons) compared to the trials of typically developing children (n=70). The MOE captures differences in mastication between individual children with cerebral palsy. The MOE items 'jaw movement' and 'fluency and coordination' showed the most similarity with the objective measurements. Objective measurements of dynamic ultrasound and 3D kinematics complemented data from the MOE instrument. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Order of stimulus presentation influences children's acquisition in receptive identification tasks.

    PubMed

    Petursdottir, Anna Ingeborg; Aguilar, Gabriella

    2016-03-01

    Receptive identification is usually taught in matching-to-sample format, which entails the presentation of an auditory sample stimulus and several visual comparison stimuli in each trial. Conflicting recommendations exist regarding the order of stimulus presentation in matching-to-sample trials. The purpose of this study was to compare acquisition in receptive identification tasks under 2 conditions: when the sample was presented before the comparisons (sample first) and when the comparisons were presented before the sample (comparison first). Participants included 4 typically developing kindergarten-age boys. Stimuli, which included birds and flags, were presented on a computer screen. Acquisition in the 2 conditions was compared in an adapted alternating-treatments design combined with a multiple baseline design across stimulus sets. All participants took fewer trials to meet the mastery criterion in the sample-first condition than in the comparison-first condition. © 2015 Society for the Experimental Analysis of Behavior.

  2. The Stability of Self-Reported Anxiety in Youth with Autism Versus ADHD or Typical Development.

    PubMed

    Schiltz, Hillary; McIntyre, Nancy; Swain-Lerro, Lindsay; Zajic, Matthew; Mundy, Peter

    2017-12-01

    Children with autism spectrum disorder (ASD) are at risk for anxiety symptoms. Few anxiety measures are validated for individuals with ASD, and the nature of ASD raises questions about reliability of self-reported anxiety. This study examined longitudinal stability and change of self-reported anxiety in higher functioning youth with ASD (HFASD) compared to youth with symptoms of attention deficit hyperactivity disorder and typical development (TD) using the Multidimensional Anxiety Scale for Children (March, 2012; March et al. J Am Acad Child Adolesc Psychiatry 36(4):554-565, 1997). Diagnostic groups demonstrated comparable evidence of stability for most dimensions of anxiety. The HFASD group displayed higher anxiety than both comparison groups, especially physical symptoms. These findings have implications for identification and measurement of anxiety in ASD.

  3. Computer model to simulate testing at the National Transonic Facility

    NASA Technical Reports Server (NTRS)

    Mineck, Raymond E.; Owens, Lewis R., Jr.; Wahls, Richard A.; Hannon, Judith A.

    1995-01-01

    A computer model has been developed to simulate the processes involved in the operation of the National Transonic Facility (NTF), a large cryogenic wind tunnel at the Langley Research Center. The simulation was verified by comparing the simulated results with previously acquired data from three experimental wind tunnel test programs in the NTF. The comparisons suggest that the computer model simulates reasonably well the processes that determine the liquid nitrogen (LN2) consumption, electrical consumption, fan-on time, and the test time required to complete a test plan at the NTF. From these limited comparisons, it appears that the results from the simulation model are generally within about 10 percent of the actual NTF test results. The use of actual data acquisition times in the simulation produced better estimates of the LN2 usage, as expected. Additional comparisons are needed to refine the model constants. The model will typically produce optimistic results since the times and rates included in the model are typically the optimum values. Any deviation from the optimum values will lead to longer times or increased LN2 and electrical consumption for the proposed test plan. Computer code operating instructions and listings of sample input and output files have been included.

  4. Federal Aviation Regulations - National Aviation Regulations of Russia

    NASA Astrophysics Data System (ADS)

    Chernykh, O.; Bakiiev, M.

    2018-03-01

    Chinese Aerospace Engineering is currently developing cooperation with Russia on a wide-body airplane project that has directed the work towards better understanding of Russian airworthiness management system. The paper introduces national Aviation regulations of Russia, presents a comparison of them with worldwide recognized regulations, and highlights typical differences. They have been found to be: two general types of regulations used in Russia (Aviation Regulations and Federal Aviation Regulations), non-unified structure of regulations on Aircraft Operation management, various separate agencies responsible for regulation issuance instead of one national aviation authority, typical confusions in references. The paper also gives a list of effective Russian Regulations of both types.

  5. Relationship between Motor and Executive Functioning in School-Age Children with Pervasive Developmental Disorder Not Otherwise Specified

    ERIC Educational Resources Information Center

    Schurink, J.; Hartman, E.; Scherder, E. J. A.; Houwen, S.; Visscher, C.

    2012-01-01

    This study examines the motor skills and executive functioning (EF) of 28 children diagnosed with pervasive developmental disorder-not otherwise specified (PDD-NOS; mean age: 10 years 6 months, range: 7-12 years; 19 boys, 9 girls) in comparison with age- and gender-matched typically developing children. The potential relationship between motor…

  6. Quality of Life of Children with Learning Disabilities: A Comparison of Self-Reports and Proxy Reports

    ERIC Educational Resources Information Center

    Sakiz, Halis; Sart, Zeynep Hande; Börkan, Bengü; Korkmaz, Baris; Babür, Nalan

    2015-01-01

    This study aimed to explore how children with learning disabilities (LD) perceive their quality of life (QoL) and to compare self-reports and proxy reports regarding their QoL. Children with LD, their typically developing peers, their parents and teachers responded to the child, parent, and teacher forms of KINDL® Questionnaire for Measuring…

  7. Effect of Sentence Length and Complexity on Working Memory Performance in Hungarian Children with Specific Language Impairment (SLI): A Cross-Linguistic Comparison

    ERIC Educational Resources Information Center

    Marton, Klara; Schwartz, Richard G.; Farkas, Lajos; Katsnelson, Valeriya

    2006-01-01

    Background: English-speaking children with specific language impairment (SLI) perform more poorly than their typically developing peers in verbal working memory tasks where processing and storage are simultaneously required. Hungarian is a language with a relatively free word order and a rich agglutinative morphology. Aims: To examine the effect…

  8. Discourse Skills of Boys with Fragile X Syndrome in Comparison to Boys with Down Syndrome

    ERIC Educational Resources Information Center

    Roberts, Joanne; Martin, Gary E.; Moskowitz, Lauren; Harris, Adrianne A.; Foreman, Jamila; Nelson, Lauren

    2007-01-01

    Purpose: This study compared the conversational discourse skills of boys who have fragile X syndrome with and without autism spectrum disorder (ASD) with those of boys with Down syndrome and boys who are typically developing. Method: Participants were boys who have fragile X syndrome with (n = 26) and without (n = 28) ASD, boys with Down syndrome…

  9. Receptive Vocabulary, Expressive Vocabulary, and Speech Production of Boys with Fragile X Syndrome in Comparison to Boys with Down Syndrome

    ERIC Educational Resources Information Center

    Roberts, Joanne; Price, Johanna; Barnes, Elizabeth; Nelson, Lauren; Burchinal, Margaret; Hennon, Elizabeth A.; Moskowitz, Lauren; Edwards, Anne; Malkin, Cheryl; Anderson, Kathleen; Misenheimer, Jan; Hooper, Stephen R.

    2007-01-01

    Boys with fragile X syndrome with (n = 49) and without (n = 33) characteristics of autism spectrum disorder, boys with Down syndrome (39), and typically developing boys (n = 41) were compared on standardized measures of receptive vocabulary, expressive vocabulary, and speech administered annually over 4 years. Three major findings emerged. Boys…

  10. A Comparison of Playfulness of Young Children with and without Autism Spectrum Disorder in Interactions with Their Mothers and Teachers

    ERIC Educational Resources Information Center

    Pinchover, Shulamit; Shulman, Cory; Bundy, Anita

    2016-01-01

    Children with autism spectrum disorder (ASD) tend to be less playful than their typically developing (TD) peers. Although playfulness is considered a personality characteristic, little is known about the stability of this trait in interactions with different caregivers. This study compared the playfulness of children with and without ASD in play…

  11. Delay of Gratification: A Comparison Study of Children with Down Syndrome, Moderate Intellectual Disability and Typical Development

    ERIC Educational Resources Information Center

    Cuskelly, M.; Gilmore, L.; Glenn, S.; Jobling, A.

    2016-01-01

    Background: Self-regulation has been found to be an important contributor to a range of outcomes, with delay of gratification (a self-regulatory skill) predicting better academic, social and personal functioning. There is some evidence that individuals with Down syndrome have difficulty with delay of gratification. We investigated the question of…

  12. Differential jumping performance in newly metamorphosed Blanchard's cricket frogs, Acris blanchardi (Anura: Hylidae), from fish- and invertebrate-dominated ponds

    Treesearch

    Taylor L. Hall; Daniel Saenz; Matthew A. Kwiatkowski

    2013-01-01

    Organisms that adopt phenotypically plastic anti-predator strategies during larval stages may incur fitness costs later in development. These costs are typically difficult to define in many species. The difficulty identifying ecological trade-offs may result from experimental comparisons that do not adequately mirror naturally occurring predator-prey relationships. To...

  13. Motor Skills in Children Aged 7-10 Years, Diagnosed with Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    Whyatt, Caroline P.; Craig, Cathy M.

    2012-01-01

    This study used the Movement Assessment Battery for Children (M-ABC2) to assess motor skills in children aged 7-10 years with autism (n = 18) in comparison to two groups of age-matched typically developing children; a receptive vocabulary matched group (n = 19) and a nonverbal IQ matched group (n = 22). The results supported previous work, as…

  14. Language in Low-Functioning Children with Autistic Disorder: Differences between Receptive and Expressive Skills and Concurrent Predictors of Language

    ERIC Educational Resources Information Center

    Maljaars, Jarymke; Noens, Ilse; Scholte, Evert; van Berckelaer-Onnes, Ina

    2012-01-01

    Language profiles of children with autistic disorder and intellectual disability (n = 36) were significantly different from the comparison groups of children with intellectual disability (n = 26) and typically developing children (n = 34). The group low-functioning children with autistic disorder obtained a higher mean score on expressive than on…

  15. Parenting Stress, Salivary Biomarkers, and Ambulatory Blood Pressure: A Comparison between Mothers and Fathers of Children with Autism Spectrum Disorders

    ERIC Educational Resources Information Center

    Foody, Ciara; James, Jack E.; Leader, Geraldine

    2015-01-01

    Parents of children with autism spectrum disorders (ASD) may experience higher levels of stress and health problems than parents of children with typical development. However, most research has focused on mothers, with emphasis on parent-reported stress and wellbeing. This study compared parenting responsibility, distress, anxiety, depression,…

  16. Use of Speaker Intent and Grammatical Cues in Fast-Mapping by Adolescents with Down Syndrome

    ERIC Educational Resources Information Center

    McDuffie, Andrea S.; Sindberg, Heidi A.; Hesketh, Linda J.; Chapman, Robin S.

    2007-01-01

    Purpose: The authors asked whether adolescents with Down syndrome (DS) could fast-map novel nouns and verbs when word learning depended on using the speaker's pragmatic or syntactic cues. Compared with typically developing (TD) comparison children, the authors predicted that syntactic cues would prove harder for the group with DS to use and that…

  17. Use of Emotional Cues for Lexical Learning: A Comparison of Autism Spectrum Disorder and Fragile X Syndrome

    ERIC Educational Resources Information Center

    Thurman, Angela John; McDuffie, Andrea; Kover, Sara T.; Hagerman, Randi; Channell, Marie Moore; Mastergeorge, Ann; Abbeduto, Leonard

    2015-01-01

    The present study evaluated the ability of males with fragile X syndrome (FXS), nonsyndromic autism spectrum disorder (ASD), or typical development to learn new words by using as a cue to the intended referent an emotional reaction indicating a successful (excitement) or unsuccessful (disappointment) search for a novel object. Performance for all…

  18. Metacognitive Reading Strategies in Learning Disability: Relations between Usage Level, Academic Self-Efficacy and Self-Concept

    ERIC Educational Resources Information Center

    Girli, Alev; Öztürk, Halil

    2017-01-01

    The purpose of this study is to investigate the relationship between the usage levels of metacognitive reading strategies by students diagnosed with specific learning disability (SLD), academic self-efficacy and the concept of self, in comparison to their typically developing (TD) peers. The data to be used in the study were collected using the…

  19. Effects of Sampling Context on Spontaneous Expressive Language in Males with Fragile X Syndrome or Down Syndrome

    ERIC Educational Resources Information Center

    Kover, Sara T.; McDuffie, Andrea; Abbeduto, Leonard; Brown, W. Ted

    2012-01-01

    Purpose: In this study, the authors examined the impact of sampling context on multiple aspects of expressive language in male participants with fragile X syndrome in comparison to male participants with Down syndrome or typical development. Method: Participants with fragile X syndrome (n = 27), ages 10-17 years, were matched groupwise on…

  20. Cross Syndrome Comparison of Sleep Problems in Children with Down Syndrome and Williams Syndrome

    ERIC Educational Resources Information Center

    Ashworth, Anna; Hill, Catherine M.; Karmiloff-Smith, Annette; Dimitriou, Dagmara

    2013-01-01

    Based on previous findings of frequent sleep problems in children with Down syndrome (DS) and Williams syndrome (WS), the present study aimed to expand our knowledge by using parent report and actigraphy to define sleep problems more precisely in these groups. Twenty-two school-aged children with DS, 24 with WS and 52 typically developing (TD)…

  1. A Pilot Study of a Kindergarten Summer School Reading Program in High-Poverty Urban Schools

    ERIC Educational Resources Information Center

    Denton, Carolyn A.; Solari, Emily J.; Ciancio, Dennis J.; Hecht, Steven A.; Swank, Paul R.

    2010-01-01

    This pilot study examined an implementation of a kindergarten summer school reading program in 4 high-poverty urban schools. The program targeted both basic reading skills and oral language development. Students were randomly assigned to a treatment group (n = 25) or a typical practice comparison group (n = 28) within each school; however,…

  2. Power Systems for Future Missions: Appendices A-L

    NASA Technical Reports Server (NTRS)

    Gill, S. P.; Frye, P. E.; Littman, Franklin D.; Meisl, C. J.

    1994-01-01

    Selection of power system technology for space applications is typically based on mass, readiness of a particular technology to meet specific mission requirements, and life cycle costs (LCC). The LCC is typically used as a discriminator between competing technologies for a single mission application. All other future applications for a given technology are usually ignored. As a result, development cost of a technology becomes a dominant factor in the LCC comparison. Therefore, it is common for technologies such as DIPS and LMR-CBC to be potentially applicable to a wide range of missions and still lose out in the initial LCC comparison due to high development costs. This collection of appendices (A through L) contains the following power systems technology plans: CBC DIPS Technology Roadmap; PEM PFC Technology Roadmap; NAS Battery Technology Roadmap; PV/RFC Power System Technology Roadmap; PV/NAS Battery Technology Roadmap; Thermionic Reactor Power System Technology Roadmap; SP-100 Power System Technology Roadmap; Dynamic SP-100 Power System Technology Roadmap; Near-Term Solar Dynamic Power System Technology Roadmap; Advanced Solar Dynamic Power System Technology Roadmap; Advanced Stirling Cycle Dynamic Isotope Power System Technology Roadmap; and the ESPPRS (Evolutionary Space Power and Propulsion Requirements System) User's Guide.

  3. Implicit learning in children and adults with Williams syndrome.

    PubMed

    Don, Audrey J; Schellenberg, E Glenn; Reber, Arthur S; DiGirolamo, Kristen M; Wang, Paul P

    2003-01-01

    In comparison to explicit learning, implicit learning is hypothesized to be a phylogenetically older form of learning that is important in early developmental processes (e.g., natural language acquisition, socialization)and relatively impervious to individual differences in age and IQ. We examined implicit learning in a group of children and adults (9.49 years of age)with Williams syndrome (WS)and in a comparison group of typically developing individuals matched for chronological age. Participants were tested in an artificial-grammar learning paradigm and in a rotor-pursuit task. For both groups, implicit learning was largely independent of age. Both groups showed evidence of implicit learning but the comparison group outperformed the WS group on both tasks. Performance advantages for the comparison group were no longer significant when group differences in working memory or nonverbal intelligence were held constant.

  4. Computing diffuse fraction of global horizontal solar radiation: A model comparison.

    PubMed

    Dervishi, Sokol; Mahdavi, Ardeshir

    2012-06-01

    For simulation-based prediction of buildings' energy use or expected gains from building-integrated solar energy systems, information on both direct and diffuse component of solar radiation is necessary. Available measured data are, however, typically restricted to global horizontal irradiance. There have been thus many efforts in the past to develop algorithms for the derivation of the diffuse fraction of solar irradiance. In this context, the present paper compares eight models for estimating diffuse fraction of irradiance based on a database of measured irradiance from Vienna, Austria. These models generally involve mathematical formulations with multiple coefficients whose values are typically valid for a specific location. Subsequent to a first comparison of these eight models, three better performing models were selected for a more detailed analysis. Thereby, the coefficients of the models were modified to account for Vienna data. The results suggest that some models can provide relatively reliable estimations of the diffuse fractions of the global irradiance. The calibration procedure could only slightly improve the models' performance.

  5. Quantitative approach for defining basic color terms and color category best exemplars.

    PubMed

    Fider, Nicole; Narens, Louis; Jameson, Kimberly A; Komarova, Natalia L

    2017-08-01

    A new method is presented that identifies basic color terms (BCTs) from color-naming data. A function is defined that measures how well a term is understood by a communicating population. BCTs are then separated from other color terms by a threshold value applied to this function. A new mathematical algorithm is proposed and analyzed for determining the best exemplar associated with each BCT. Using data provided by the World Color Survey, comparisons are made between the paper's methods and those from other studies. These comparisons show that the paper's new definition of "basicness" mostly agrees with the typical definition found in the color categorization literature, which was originally due to Kay and colleagues. The new definition, unlike the typical one, has the advantage of not relying on syntactic or semantic features of languages or color lexicons. This permits the methodology developed to be generalizable and applied to other category domains for which a construct of "basicness" could have an important role.

  6. Measurement of fault latency in a digital avionic miniprocessor

    NASA Technical Reports Server (NTRS)

    Mcgough, J. G.; Swern, F. L.

    1981-01-01

    The results of fault injection experiments utilizing a gate-level emulation of the central processor unit of the Bendix BDX-930 digital computer are presented. The failure detection coverage of comparison-monitoring and a typical avionics CPU self-test program was determined. The specific tasks and experiments included: (1) inject randomly selected gate-level and pin-level faults and emulate six software programs using comparison-monitoring to detect the faults; (2) based upon the derived empirical data develop and validate a model of fault latency that will forecast a software program's detecting ability; (3) given a typical avionics self-test program, inject randomly selected faults at both the gate-level and pin-level and determine the proportion of faults detected; (4) determine why faults were undetected; (5) recommend how the emulation can be extended to multiprocessor systems such as SIFT; and (6) determine the proportion of faults detected by a uniprocessor BIT (built-in-test) irrespective of self-test.

  7. Stress among Parents of Children with and without Autism Spectrum Disorder: A Comparison Involving Physiological Indicators and Parent Self-Reports.

    PubMed

    Padden, Ciara; James, Jack E

    2017-01-01

    Parents of children with Autism Spectrum Disorder (ASD) have been reported as experiencing higher levels of stress and poorer physical health than parents of typically developing children. However, most of the relevant literature has been based on parental self-reports of stress and health. While research on physiological outcomes has grown in recent years, gaps still exist in our understanding of the physiological effects, if any, of stress related to parenting a child with ASD. The present study compared parent-reported stress, anxiety, and depression, as well as selected physiological measures of stress (i.e., cortisol, alpha-amylase, and ambulatory blood pressure and heart rate) between matched groups of parents of children with ( N =  38) and without ( N  = 38) ASD. Participants completed questionnaires, collected saliva samples for the purpose of measuring cortisol and alpha-amylase, and wore an ambulatory blood pressure monitor for 24 h. Parents of children with ASD reported significantly higher levels of parental distress, anxiety, and depression than parents of typically developing children. Parent-reported distress, anxiety, depression, and health were not correlated with physiological measures. With the exception that parents of children with ASD had significantly lower cortisol levels 30 min after waking, no other significant group differences were found for physiological measures. Parents of children with ASD reported significantly higher use of a number of adaptive coping strategies (e.g., emotional support) in comparison to parents of typically developing children. Results are discussed in the context of implications for future research directions, stress research, and practical implications for parental support.

  8. Prediction of space shuttle fluctuating pressure environments, including rocket plume effects

    NASA Technical Reports Server (NTRS)

    Plotkin, K. J.; Robertson, J. E.

    1973-01-01

    Preliminary estimates of space shuttle fluctuating pressure environments have been made based on prediction techniques developed by Wyle Laboratories. Particular emphasis has been given to the transonic speed regime during launch of a parallel-burn space shuttle configuration. A baseline configuration consisting of a lightweight orbiter and monolithic SRB, together with a typical flight trajectory, have been used as models for the predictions. Critical fluctuating pressure environments are predicted at transonic Mach numbers. Comparisons between predicted environments and wind tunnel test results, in general, showed good agreement. Predicted one-third octave band spectra for the above environments were generally one of three types: (1) attached turbulent boundary layer spectra (typically high frequencies); (2) homogeneous separated flow and shock-free interference flow spectra (typically intermediate frequencies); and (3) shock-oscillation and shock-induced interference flow spectra (typically low frequencies). Predictions of plume induced separated flow environments were made. Only the SRB plumes are important, with fluctuating levels comparable to compression-corner induced separated flow shock oscillation.

  9. The Development of English as a Second Language With and Without Specific Language Impairment: Clinical Implications.

    PubMed

    Paradis, Johanne

    2016-02-01

    The purpose of this research forum article is to provide an overview of typical and atypical development of English as a second language (L2) and to present strategies for clinical assessment with English language learners (ELLs). A review of studies examining the lexical, morphological, narrative, and verbal memory abilities of ELLs is organized around 3 topics: timeframe and characteristics of typical English L2 development, comparison of the English L2 development of children with and without specific language impairment (SLI), and strategies for more effective assessment with ELLs. ELLs take longer than 3 years to converge on monolingual norms and approach monolingual norms asynchronously across linguistic subdomains. Individual variation is predicted by age, first language, language learning aptitude, length of exposure to English in school, maternal education, and richness of the English environment outside school. ELLs with SLI acquire English more slowly than ELLs with typical development; their morphological and nonword repetition abilities differentiate them the most. Use of strategies such as parent questionnaires on first language development and ELL norm referencing can result in accurate discrimination of ELLs with SLI. Variability in the language abilities of ELLs presents challenges for clinical practice. Increased knowledge of English language learning development with and without SLI together with evidence-based alternative assessment strategies can assist in overcoming these challenges.

  10. Effect of Speaker Gaze on Word Learning in Fragile X Syndrome: A Comparison with Nonsyndromic Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    Benjamin, David P.; McDuffie, Andrea S.; Thurman, Angela J.; Kover, Sara T.; Mastergeorge, Ann M.; Hagerman, Randi J.; Abbeduto, Leonard

    2015-01-01

    Purpose: This study examined use of a speaker's direction of gaze during word learning by boys with fragile X syndrome (FXS), boys with nonsyndromic autism spectrum disorder (ASD), and typically developing (TD) boys. Method: A fast-mapping task with follow-in and discrepant labeling conditions was administered. We expected that the use of speaker…

  11. Building a Community of Scholars: One University's Comparison of "Typical" vs. Open Ended Ethics Case Studies in First-Year Engineering

    ERIC Educational Resources Information Center

    Reid, Kenneth J.

    2012-01-01

    Ethics is among the professional skills embedded in the first year engineering curriculum in many institutions. The general format of the study of ethics is similar to many other institutions: student teams review case studies and develop written and oral presentations on the ethical issues encountered. This report investigates whether the use of…

  12. A Preliminary Study of Gender Differences in Autobiographical Memory in Children with an Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    Goddard, Lorna; Dritschel, Barbara; Howlin, Patricia

    2014-01-01

    Autobiographical memory was assessed in 24 children (12 male, 12 female, aged between 8 and 16 years) with autism spectrum disorder (ASD) and a comparison group of 24 typically developing (TD) children matched for age, IQ, gender and receptive language. Results suggested that a deficit in specific memory retrieval in the ASD group was more…

  13. Using a Virtual Classroom Environment to Describe the Attention Deficits Profile of Children with Neurofibromatosis Type 1

    ERIC Educational Resources Information Center

    Gilboa, Yafit; Rosenblum, Sara; Fattal-Valevski, Aviva; Toledano-Alhadef, Hagit; Rizzo, Albert; Josman, Naomi

    2011-01-01

    The objectives of this study were to describe the nature of the attention deficits in children with Neurofibromatosis type 1 (NF1) in comparison with typically developing (TD) children, using the Virtual Classroom (VC), and to assess the utility of this instrument for detecting attention deficits. Twenty-nine NF1 children and 25 age-and…

  14. Subject-Verb Agreement and Verbal Short-Term Memory: A Perspective from Greek Children with Specific Language Impairment

    ERIC Educational Resources Information Center

    Lalioti, Marina; Stavrakaki, Stavroula; Manouilidou, Christina; Talli, Ioanna

    2016-01-01

    This study investigated the performance of school age Greek-speaking children with SLI on verbal short-term memory (VSTM) and Subject-Verb (S-V) agreement in comparison to chronological age controls and younger typically developing children. VSTM abilities were assessed by means of a non-word repetition task (NRT) and an elicited production task,…

  15. Reading Accuracy and Speed of Vowelized and Unvowelized Scripts among Dyslexic Readers of Hebrew: The Road Not Taken

    ERIC Educational Resources Information Center

    Schiff, Rachel; Katzir, Tami; Shoshan, Noa

    2013-01-01

    The present study examined the effects of orthographic transparency on reading ability of children with dyslexia in two Hebrew scripts. The study explored the reading accuracy and speed of vowelized and unvowelized Hebrew words of fourth-grade children with dyslexia. A comparison was made to typically developing readers of two age groups: a group…

  16. Production of Landsat ETM+ reference imagery of burned areas within Southern African savannahs: comparison of methods and application to MODIS

    Treesearch

    A. M. S. Smith; N. A. Drake; M. J. Wooster; A. T. Hudak; Z. A. Holden; C. J. Gibbons

    2007-01-01

    Accurate production of regional burned area maps are necessary to reduce uncertainty in emission estimates from African savannah fires. Numerous methods have been developed that map burned and unburned surfaces. These methods are typically applied to coarse spatial resolution (1 km) data to produce regional estimates of the area burned, while higher spatial resolution...

  17. Physiological Arousal in Autism and Fragile X Syndrome: Group Comparisons and Links with Pragmatic Language

    ERIC Educational Resources Information Center

    Klusek, Jessica; Martin, Gary E.; Losh, Molly

    2013-01-01

    This study tested the hypothesis that pragmatic (i.e., social) language impairment is linked to arousal dysregulation in autism spectrum disorder (ASD) and fragile X syndrome (FXS). Forty boys with ASD, 39 with FXS, and 27 with typical development (TD), aged 4-15 years, participated. Boys with FXS were hyperaroused compared to boys with TD but did…

  18. Mind and Body: Concepts of Human Cognition, Physiology and False Belief in Children with Autism or Typical Development

    ERIC Educational Resources Information Center

    Peterson, Candida C.

    2005-01-01

    This study examined theory of mind (ToM) and concepts of human biology (eyes, heart, brain, lungs and mind) in a sample of 67 children, including 25 high functioning children with autism (age 6-13), plus age-matched and preschool comparison groups. Contrary to Baron-Cohen [1989, "Journal of Autism and Developmental Disorders," 19(4),…

  19. The Impact of Parenting Stress: A Meta-Analysis of Studies Comparing the Experience of Parenting Stress in Parents of Children with and without Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    Hayes, Stephanie A.; Watson, Shelley L.

    2013-01-01

    Researchers commonly report that families of children with autism spectrum disorder (ASD) experience more parenting stress than families of typically developing (TD) children or those diagnosed with other disabilities [e.g., Down syndrome (DS), cerebral palsy, intellectual disability]. The authors reexamined the research using comparison groups to…

  20. Low-Skilled Adult Readers Look Like Typically Developing Child Readers: A Comparison of Reading Skills and Eye Movement Behavior

    ERIC Educational Resources Information Center

    Barnes, Adrienne E.; Kim, Young-Suk

    2016-01-01

    Adults enrolled in basic education exhibit poor academic performance, often reading at elementary and middle-school levels. The current study investigated the similarities and differences of reading skills and eye movement behavior between a sample of 25 low-skilled adult readers and 25 first grade students matched on word reading skill. t tests…

  1. Educational Ideas in Geography Education in Sweden during the Nineteenth and Early Twentieth Centuries: The Relationship between Maps and Texts

    ERIC Educational Resources Information Center

    Hennerdal, Pontus

    2015-01-01

    Descriptions of the geography education of the nineteenth and early twentieth centuries in Sweden are typically offered to contrast with current ideas in geography education, and the content of geography textbooks is the focus of this comparison. The role of maps and visual pedagogy are ignored, and the educational ideas developed from regional…

  2. Overlapping Phenotypes in Autism Spectrum Disorder and Developmental Coordination Disorder: A Cross-Syndrome Comparison of Motor and Social Skills

    ERIC Educational Resources Information Center

    Sumner, Emma; Leonard, Hayley C.; Hill, Elisabeth L.

    2016-01-01

    Motor and social difficulties are often found in children with an autism spectrum disorder (ASD) and with developmental coordination disorder (DCD), to varying degrees. This study investigated the extent of overlap of these problems in children aged 7-10 years who had a diagnosis of either ASD or DCD, compared to typically-developing controls.…

  3. Sustained Attention in Children with Primary Language Impairment: A Meta-Analysis

    PubMed Central

    Ebert, Kerry Danahy; Kohnert, Kathryn

    2014-01-01

    Purpose This study provides a meta-analysis of the difference between children with primary or specific language impairment (LI) and their typically developing peers on tasks of sustained attention. The meta-analysis seeks to determine if children with LI demonstrate subclinical deficits in sustained attention and, if so, under what conditions. Methods Articles that reported empirical data from the performance of children with LI, in comparison to typically developing peers, on a task assessing sustained attention were considered for inclusion. Twenty-eight effect sizes were included in the meta-analysis. Two moderator analyses addressed the effects of stimulus modality and ADHD exclusion. In addition, reaction time outcomes and the effects of task variables were summarized qualitatively. Results The meta-analysis supports the existence of sustained attention deficits in children with LI in both auditory and visual modalities, as demonstrated by reduced accuracy compared to typically developing peers. Larger effect sizes are found in tasks that use auditory and linguistic stimuli than in studies that use visual stimuli. Conclusions Future research should consider the role that sustained attention weaknesses play in LI, as well as the implications for clinical and research assessment tasks. Methodological recommendations are summarized. PMID:21646419

  4. Sustained attention in children with primary language impairment: a meta-analysis.

    PubMed

    Ebert, Kerry Danahy; Kohnert, Kathryn

    2011-10-01

    This study provides a meta-analysis of the difference between children with primary or specific language impairment (LI) and their typically developing peers on tasks of sustained attention. The meta-analysis seeks to determine whether children with LI demonstrate subclinical deficits in sustained attention and, if so, under what conditions. Articles that reported empirical data from the performance of children with LI, in comparison to typically developing peers, on a task assessing sustained attention were considered for inclusion. Twenty-eight effect sizes were included in the meta-analysis. Two moderator analyses addressed the effects of stimulus modality and attention-deficit/hypereactivity disorder exclusion. In addition, reaction time outcomes and the effects of task variables were summarized qualitatively. The meta-analysis supports the existence of sustained attention deficits in children with LI in both auditory and visual modalities, as demonstrated by reduced accuracy compared with typically developing peers. Larger effect sizes are found in tasks that use auditory-linguistic stimuli than in studies that use visual stimuli. Future research should consider the role that sustained attention weaknesses play in LI as well as the implications for clinical and research assessment tasks. Methodological recommendations are summarized.

  5. Thorax and pelvis kinematics during walking, a comparison between children with and without cerebral palsy: A systematic review.

    PubMed

    Swinnen, Eva; Goten, Laura Vander; De Koster, Berdien; Degelaen, Marc

    2016-01-01

    Dysfunctional postural control and pathological thorax and pelvis motions are often observed in children with cerebral palsy (CP) and can be considered as an indicator of diminished dynamic stability. The aim of this study was to identify the differences between children with CP and typically developing children in three-dimensional thorax and pelvis kinematics during walking. Three electronic databases were searched by using different combinations of keywords. The methodological quality of the studies was assessed by two researchers with the Strobe quality checklist. Ten studies (methodological quality: 32% to 74%) with in total 259 children with CP and 220 typically developing children (mean age: 7.6 to 13.6 year) were included. Compared to typically developing children, children with bilateral CP showed an increased range of motion of the thorax, pelvis and spine during walking. The results of the children with unilateral CP were less clear. In general, children with bilateral CP showed larger movement amplitudes of the trunk compared to children without CP. This increase in movement amplitudes could influence the dynamic stability of the body during walking. In children with unilateral CP, the results were less obvious and further research on this topic is required.

  6. Ambulatory Physical Activity Performance in Youth With Cerebral Palsy and Youth Who Are Developing Typically

    PubMed Central

    Bjornson, Kristie F; Belza, Basia; Kartin, Deborah; Logsdon, Rebecca; McLaughlin, John F

    2007-01-01

    Background and Purpose Assessment of walking activity in youth with cerebral palsy (CP) has traditionally been “capacity-based.” The purpose of this study was to describe the day-to-day ambulatory activity “performance” of youth with CP compared with youth who were developing typically. Subjects Eighty-one youth with CP, aged 10 to 13 years, who were categorized as being in Gross Motor Function Classification System (GMFCS) levels I to III and 30 age-matched youth who were developing typically were recruited. Methods Using a cross-sectional design, participants wore the StepWatch monitor for 7 days while documenting average daily total step counts, percentage of all time active, ratio of medium to low activity levels, and percentage of time at high activity levels. Results The youth with CP demonstrated significantly lower levels of all outcomes than the comparison group. Discussion and Conclusion Daily walking activity and variability decreased as functional walking level (GMFCS level) decreased. Ambulatory activity performance within the context of the daily life for youth with CP appears valid and feasible as an outcome for mobility interventions in CP. PMID:17244693

  7. The Peer Social Networks of Young Children with Down Syndrome in Classroom Programmes

    PubMed Central

    Guralnick, Michael J.; Connor, Robert T.; Johnson, L. Clark

    2010-01-01

    Background The nature and characteristics of the peer social networks of young children with Down syndrome in classroom settings were examined within a developmental framework. Method Comparisons were made with younger typically developing children matched on mental age and typically developing children matched on chronological age. Results Similar patterns were found for all three groups for most peer social network measures. However, group differences were obtained for measures of teacher assistance and peer interactions in unstructured situations. Conclusions Positive patterns appeared to be related to the social orientation of children with Down syndrome and the special efforts of teachers to support children’s peer social networks. Findings also suggested that fundamental peer competence problems for children with Down syndrome remain and may best be addressed within the framework of contemporary models of peer-related social competence. PMID:21765644

  8. Fetal head circumference growth in children with specific language impairment.

    PubMed

    Whitehouse, Andrew J O; Zubrick, Stephen R; Blair, Eve; Newnham, John P; Hickey, Martha

    2012-01-01

    To characterise fetal brain growth in children with specific language impairment (SLI). A nested case-control study. Perth, Western Australia. Thirty children meeting criteria for SLI at age 10 years were individually matched with a typically developing comparison child on sex, non-verbal ability, fetal gestational age, maternal age at conception, smoking and alcohol intake during pregnancy. Occipitofrontal head circumference (HC) was measured using ultrasonography at approximately 18 weeks gestation. Femur length provided a measure of fetal length. Occipitofrontal HC was measured at birth and at the 1-year postnatal follow-up using a precise paper tape measure, while crown-heel length acted as an index of body length at both time points. Raw data were transformed to z-scores using reference norms. The SLI group had a significantly smaller mean HC than the typically developing comparison children at birth, but there was no group difference at 18 weeks gestation or at the 1-year postnatal follow-up. Individual analyses found that 12 SLI children had an HC z-score less than -1 at birth, with three of these cases meeting criteria for microcephaly. There was no group difference in the indices of overall body size at any time point. Children with SLI are more likely to have a small HC at birth but not at 18 weeks gestation or infancy, suggesting growth asynchrony in brain development during the second half of pregnancy.

  9. Neurocognitive Functioning in Patients with 22q11.2 Deletion Syndrome: A Meta-Analytic Review.

    PubMed

    Moberg, Paul J; Richman, Mara J; Roalf, David R; Morse, Chelsea L; Graefe, Anna C; Brennan, Laura; Vickers, Kayci; Tsering, Wangchen; Kamath, Vidyulata; Turetsky, Bruce I; Gur, Ruben C; Gur, Raquel E

    2018-06-19

    The 22q11.2 deletion syndrome (22q11.2DS) is a known risk factor for development of schizophrenia and is characterized by a complex neuropsychological profile. To date, a quantitative meta-analysis examining cognitive functioning in 22q11.2DS has not been conducted. A systematic review of cross-sectional studies comparing neuropsychological performance of individuals with 22q11.2DS with age-matched healthy typically developing and sibling comparison subjects was carried out. Potential moderators were analyzed. Analyses included 43 articles (282 effects) that met inclusion criteria. Very large and heterogeneous effects were seen for global cognition (d = - 1.21) and in specific neuropsychological domains (intellectual functioning, achievement, and executive function; d range = - 0.51 to - 2.43). Moderator analysis revealed a significant role for type of healthy comparison group used (typically developing or siblings), demographics (age, sex) and clinical factors (externalizing behavior). Results revealed significant differences between pediatric and adult samples, with isolated analysis within the pediatric sample yielding large effects in several neuropsychological domains (intellectual functioning, achievement, visual memory; d range = - 0.56 to - 2.50). Large cognitive deficits in intellectual functioning and specific neuropsychological variables in individuals with 22q11.2DS represent a robust finding, but these deficits are influenced by several factors, including type of comparison group utilized, age, sex, and clinical status. These findings highlight the clinical relevance of characterizing cognitive functioning in 22q11.2DS and the importance of considering demographic and clinical moderators in future analyses.

  10. The Influence of Phonotactic Probability on Nonword Repetition and Fast Mapping in 3-Year-Olds With a History of Expressive Language Delay.

    PubMed

    MacRoy-Higgins, Michelle; Dalton, Kevin Patrick

    2015-12-01

    The purpose of this study was to examine the influence of phonotactic probability on sublexical (phonological) and lexical representations in 3-year-olds who had a history of being late talkers in comparison with their peers with typical language development. Ten 3-year-olds who were late talkers and 10 age-matched typically developing controls completed nonword repetition and fast mapping tasks; stimuli for both experimental procedures differed in phonotactic probability. Both participant groups repeated nonwords containing high phonotactic probability sequences more accurately than nonwords containing low phonotactic probability sequences. Participants with typical language showed an early advantage for fast mapping high phonotactic probability words; children who were late talkers required more exposures to the novel words to show the same advantage for fast mapping high phonotactic probability words. Children who were late talkers showed similar sensitivities to phonotactic probability in nonword repetition and word learning when compared with their peers with no history of language delay. However, word learning in children who were late talkers appeared to be slower when compared with their peers.

  11. Comparison of Low-Thrust Control Laws for Application in Planetocentric Space

    NASA Technical Reports Server (NTRS)

    Falck, Robert D.; Sjauw, Waldy K.; Smith, David A.

    2014-01-01

    Recent interest at NASA for the application of solar electric propulsion for the transfer of significant payloads in cislunar space has led to the development of high-fidelity simulations of such missions. With such transfers involving transfer times on the order of months, simulation time can be significant. In the past, the examination of such missions typically began with the use of lower-fidelity trajectory optimization tools such as SEPSPOT to develop and tune guidance laws which delivered optimal or near- optimal trajectories, where optimal is generally defined as minimizing propellant expenditure or time of flight. The transfer of these solutions to a high-fidelity simulation is typically an iterative process whereby the initial solution may nearly, but not precisely, meet mission objectives. Further tuning of the guidance algorithm is typically necessary when accounting for high-fidelity perturbations such as those due to more detailed gravity models, secondary-body effects, solar radiation pressure, etc. While trajectory optimization is a useful method for determining optimal performance metrics, algorithms which deliver nearly optimal performance with minimal tuning are an attractive alternative.

  12. Language in low-functioning children with autistic disorder: differences between receptive and expressive skills and concurrent predictors of language.

    PubMed

    Maljaars, Jarymke; Noens, Ilse; Scholte, Evert; van Berckelaer-Onnes, Ina

    2012-10-01

    Language profiles of children with autistic disorder and intellectual disability (n = 36) were significantly different from the comparison groups of children with intellectual disability (n = 26) and typically developing children (n = 34). The group low-functioning children with autistic disorder obtained a higher mean score on expressive than on receptive language, whereas both comparison groups showed the reverse pattern. Nonverbal mental age, joint attention, and symbolic understanding of pictures were analyzed in relation to concurrent receptive and expressive language abilities. In the group with autistic disorder and intellectual disability, symbol understanding and joint attention were most strongly related to language abilities. Nonverbal mental age was the most important predictor of language abilities in the comparison groups.

  13. STARS: The Space Transportation Architecture Risk System

    NASA Technical Reports Server (NTRS)

    Greenberg, Joel S.

    1997-01-01

    Because of the need to perform comparisons between transportation systems that are likely to have significantly different levels of risk, both because of differing degrees of freedom in achieving desired performance levels and their different states of development and utilization, an approach has been developed for performing early comparisons of transportation architectures explicitly taking into account quantitative measures of uncertainty and resulting risk. The approach considers the uncertainty associated with the achievement of technology goals, the effect that the achieved level of technology will have on transportation system performance and the relationship between transportation system performance/capability and the ability to accommodate variations in payload mass. The consequences of system performance are developed in terms of expected values and associated standard deviations of nonrecurring, recurring and the present value of transportation system life cycle cost. Typical results are presented to illustrate the application of the methodology.

  14. The contrast between alveolar and velar stops with typical speech data: acoustic and articulatory analyses.

    PubMed

    Melo, Roberta Michelon; Mota, Helena Bolli; Berti, Larissa Cristina

    2017-06-08

    This study used acoustic and articulatory analyses to characterize the contrast between alveolar and velar stops with typical speech data, comparing the parameters (acoustic and articulatory) of adults and children with typical speech development. The sample consisted of 20 adults and 15 children with typical speech development. The analyzed corpus was organized through five repetitions of each target-word (/'kap ə/, /'tapə/, /'galo/ e /'daɾə/). These words were inserted into a carrier phrase and the participant was asked to name them spontaneously. Simultaneous audio and video data were recorded (tongue ultrasound images). The data was submitted to acoustic analyses (voice onset time; spectral peak and burst spectral moments; vowel/consonant transition and relative duration measures) and articulatory analyses (proportion of significant axes of the anterior and posterior tongue regions and description of tongue curves). Acoustic and articulatory parameters were effective to indicate the contrast between alveolar and velar stops, mainly in the adult group. Both speech analyses showed statistically significant differences between the two groups. The acoustic and articulatory parameters provided signals to characterize the phonic contrast of speech. One of the main findings in the comparison between adult and child speech was evidence of articulatory refinement/maturation even after the period of segment acquisition.

  15. Comparison among Children with Children with Autism Spectrum Disorder, Nonverbal Learning Disorder and Typically Developing Children on Measures of Executive Functioning

    ERIC Educational Resources Information Center

    Semrud-Clikeman, Margaret; Fine, Jodene Goldenring; Bledsoe, Jesse

    2014-01-01

    It has been suggested that children with nonverbal learning disabilities (NLD) or Asperger's Syndrome (AS) may show difficulties with executive functioning. There were 3 groups in this study who completed a neuropsychological battery of visual-spatial, executive functioning, and reasoning tasks; AS (n = 37), NLD (n = 31), and controls…

  16. The Influence of Phonotactic Probability on Nonword Repetition and Fast Mapping in 3-Year-Olds with a History of Expressive Language Delay

    ERIC Educational Resources Information Center

    MacRoy-Higgins, Michelle; Dalton, Kevin Patrick

    2015-01-01

    Purpose: The purpose of this study was to examine the influence of phonotactic probability on sublexical (phonological) and lexical representations in 3-year-olds who had a history of being late talkers in comparison with their peers with typical language development. Method: Ten 3-year-olds who were late talkers and 10 age-matched typically…

  17. Apollo experience report: Mission planning for lunar module descent and ascent

    NASA Technical Reports Server (NTRS)

    Bennett, F. V.

    1972-01-01

    The premission planning, the real-time situation, and the postflight analysis for the Apollo 11 lunar descent and ascent are described. A comparison between premission planning and actual results is included. A navigation correction capability, developed from Apollo 11 postflight analysis was used successfully on Apollo 12 to provide the first pinpoint landing. An experience summary, which illustrates typical problems encountered by the mission planners, is also included.

  18. Sensitivity to Morphosyntactic Information in 3-Year-Old Children With Typical Language Development: A Feasibility Study.

    PubMed

    Deevy, Patricia; Leonard, Laurence B; Marchman, Virginia A

    2017-03-01

    This study tested the feasibility of a method designed to assess children's sensitivity to tense/agreement information in fronted auxiliaries during online comprehension of questions (e.g., Are the nice little dogs running?). We expected that a group of children who were proficient in auxiliary use would show this sensitivity, indicating an awareness of the relation between the subject-verb sequence (e.g., dogs running) and preceding information (e.g., are). Failure to grasp this relation is proposed to play a role in the protracted inconsistency in auxiliary use in children with specific language impairment (SLI). Fifteen 3-year-old typically developing children who demonstrated proficiency in auxiliary use viewed pairs of pictures showing a single agent and multiple agents while hearing questions with or without an agreeing fronted auxiliary. Proportion looking to the target was measured. Children showed anticipatory looking on the basis of the number information contained in the auxiliary (is or are). The children tested in this study represent a group that frequently serves as a comparison for older children with SLI. Because the method successfully demonstrated their sensitivity to tense/agreement information in questions, future research that involves direct comparisons of these 2 groups is warranted.

  19. Joint attention in parent-child dyads involving children with selective mutism: a comparison between anxious and typically developing children.

    PubMed

    Nowakowski, Matilda E; Tasker, Susan L; Cunningham, Charles E; McHolm, Angela E; Edison, Shannon; Pierre, Jeff St; Boyle, Michael H; Schmidt, Louis A

    2011-02-01

    Although joint attention processes are known to play an important role in adaptive social behavior in typical development, we know little about these processes in clinical child populations. We compared early school age children with selective mutism (SM; n = 19) versus mixed anxiety (MA; n = 18) and community controls (CC; n = 26) on joint attention measures coded from direct observations with their parent during an unstructured free play task and two structured tasks. As predicted, the SM dyads established significantly fewer episodes of joint attention through parental initiation acts than the MA and CC dyads during the structured tasks. Findings suggest that children with SM may withdraw from their parents during stressful situations, thus missing out on opportunities for learning other coping skills. We discuss the implications of the present findings for understanding the maintenance and treatment of SM.

  20. Participation Patterns of Preschool Children With Intellectual Developmental Disabilities.

    PubMed

    Gilboa, Yafit; Fuchs, Reut

    2018-04-01

    We aim to examine the pattern of participation of children with intellectual developmental disabilities (IDD) or global developmental delay (GDD) in comparison with typically developing preschoolers. In addition, to identify environmental and personal factors associated with their participation, 20 children with mild to moderate GDD or IDD, and 24 age- and gender-matched controls, aged 3 to 6 years, were assessed using the Assessment of Preschool Children's Participation and the Environmental Restriction Questionnaire. Significant differences were found between the groups, both for general scales of participation and for each activity area. For the IDD/GDD group, participation was significantly negatively correlated with environmental restrictions at home. For the control group, participation was correlated with demographic variables. Typically developing children participate at a higher frequency and in a more diverse range of activities compared with children with IDD/GDD. Associations between participation and contextual factors varied depending on the child's health condition.

  1. Analysis and Comparison on the Flood Simulation in Typical Hilly & Semi-mountainous Region

    NASA Astrophysics Data System (ADS)

    Luan, Qinghua; Wang, Dong; Zhang, Xiang; Liu, Jiahong; Fu, Xiaoran; Zhang, Kun; Ma, Jun

    2017-12-01

    Water-logging and flood are both serious in hilly and semi-mountainous cities of China, but the related research is rare. Lincheng Economic Development Zone (EDZ) in Hebei Province as the typical city was selected and storm water management model (SWMM) was applied for flood simulation in this study. The regional model was constructed through calibrating and verifying the runoff coefficient of different flood processes. Different designed runoff processes in five-year, ten-year and twenty-year return periods in basic scenario and in the low impact development (LID) scenario, respectively, were simulated and compared. The result shows that: LID measures have effect on peak reduction in the study area, but the effectiveness is not significant; the effectiveness of lagging peak time is poor. These simulation results provide decision support for the rational construction of LID in the study area, and provide the references for regional rain flood management.

  2. Word-initial /r/-clusters in Swedish speaking children with typical versus protracted phonological development.

    PubMed

    Lundeborg Hammarström, Inger

    2018-01-01

    The present study investigated word-initial (WI) /r/-clusters in Central Swedish-speaking children with and without protracted phonological development (PPD). Data for WI singleton /r/ and singleton and cluster /l/ served as comparisons. Participants were twelve 4-year-olds with PPD and twelve age- and gender-matched typically developing (TD) controls. Native speakers audio-recorded and transcribed 109 target single words using a Swedish phonology test with 12 WI C+/r/-clusters and three WI CC+/r/-clusters. The results showed significantly higher match scores for the TD children, a lower match proportion for the /r/ targets and for singletons compared with clusters, and differences in mismatch patterns between the groups. There were no matches for /r/-cluster targets in the PPD group, with all children except two in that group showing deletions for both /r/-cluster types. The differences in mismatch proportions and types between the PPD group and controls suggests new directions for future clinical practice.

  3. Paying attention to attention: evidence for an attentional contribution to the size congruity effect.

    PubMed

    Risko, Evan F; Maloney, Erin A; Fugelsang, Jonathan A

    2013-08-01

    Understanding the mechanisms supporting our comprehension of magnitude information represents a key goal in cognitive psychology. A major phenomenon employed in the pursuit of this goal has been the physical size congruity effect-namely, the observation that comparing the relative numerical sizes of two numbers is influenced by their relative physical sizes. The standard account of the physical size congruity effect attributes it to the automatic influence of the comparison of irrelevant physical magnitudes on numerical judgments. Here we develop an alternative account of this effect on the basis of the operation of attention in the typical size congruity display and the temporal dynamics of number comparison. We also provide a test of a number of predictions derived from this alternative account by combining a physical size congruity manipulation with a manipulation designed to alter the operation of attention within the typical size congruity display (i.e., a manipulation of the relative onsets of the digits). This test provides evidence consistent with an attentional contribution to the size congruity effect. Implications for our understanding of magnitude and the interactions between attention and magnitude are discussed.

  4. Ultrasound analysis of tongue contour for the sound [j] in adults and children.

    PubMed

    Barberena, Luciana da Silva; Simoni, Simone Nicolini de; Souza, Rosalina Correa Sobrinho de; Moraes, Denis Altieri de Oliveira; Berti, Larissa Cristina; Keske-Soares, Márcia

    2017-12-11

    Analyze and compare the mean tongue contours and articulatory gestures in the production of the sound [j] in adults and children with typical and atypical speech development. The children with atypical development presented speech sound disorders. The diagnosis was determined by speech assessments. The study sample was composed of 90 individuals divided into three groups: 30 adults with typical speech development aged 19-44 years (AT), 30 children with typical speech development (CT), and 30 children with speech sound disorders, named as atypical in this study, aged four years to eight years and eleven months (CA). Ultrasonography assessment of tongue movements was performed for all groups. Mean tongue contours were compared between three groups in different vocalic contexts following the sound [j]. The maximum elevation of the tongue tip was considered for delimitation of gestures using the Articulate Assistant Advanced (AAA) software and images in sagittal plane/Mode B. The points that intercepted the language curves were analyzed by the statistical tool R. The graphs of tongue contours were obtained adopting a 95% confidence interval. After that, the regions with significant statistical differences (p<0.05) between the CT and CA groups were obtained. The mean tongue contours demonstrated the gesture for the sound [j] in the comparison between typical and atypical children. For the semivowel [j], there is an articulatory gesture of tongue and dorsum towards the center of ​​the hard palate, with significant differences observed between the children. The results showed differences between the groups of children regarding the ability to refine articulatory gestures.

  5. The peer relationships of girls with ASD at school: comparison to boys and girls with and without ASD.

    PubMed

    Dean, Michelle; Kasari, Connie; Shih, Wendy; Frankel, Fred; Whitney, Rondalyn; Landa, Rebecca; Lord, Catherine; Orlich, Felice; King, Bryan; Harwood, Robin

    2014-11-01

    This study examines the social relationships of elementary school children with high-functioning autism, focusing on how gender relates to social preferences and acceptance, social connections, reciprocal friendships, and rejection. Peer nomination data were analyzed for girls with and without ASD (n = 50) and boys with and without ASD (n = 50). Girls and boys with ASD were matched by age, gender, and IQ. Each child with ASD was matched by age and gender to a typically developing classmate. Consistent with typically developing populations, children with ASD preferred, were accepted by, and primarily socialized with same-gender friends. With fewer nominations and social relationships, girls and boys with ASD appear more socially similar to each other than to the same-gender control group. Additionally, girls and boys with ASD showed higher rates of social exclusion than their typically developing peers. However, boys with ASD were more overtly socially excluded compared to girls with ASD, who seemed to be overlooked, rather than rejected. Our data suggest a number of interesting findings in the social relationships of children with ASD in schools. Like typically developing populations, children with ASD identify with their own gender when socializing and choosing friends. But given the social differences between genders, it is likely that girls with ASD are experiencing social challenges that are different from boys with ASD. Therefore, gender is an important environmental factor to consider when planning social skills interventions at school. © 2014 The Authors. Journal of Child Psychology and Psychiatry. © 2014 Association for Child and Adolescent Mental Health.

  6. A Deterministic Computational Procedure for Space Environment Electron Transport

    NASA Technical Reports Server (NTRS)

    Nealy, John E.; Chang, C. K.; Norman, Ryan B.; Blattnig, Steve R.; Badavi, Francis F.; Adamcyk, Anne M.

    2010-01-01

    A deterministic computational procedure for describing the transport of electrons in condensed media is formulated to simulate the effects and exposures from spectral distributions typical of electrons trapped in planetary magnetic fields. The primary purpose for developing the procedure is to provide a means of rapidly performing numerous repetitive transport calculations essential for electron radiation exposure assessments for complex space structures. The present code utilizes well-established theoretical representations to describe the relevant interactions and transport processes. A combined mean free path and average trajectory approach is used in the transport formalism. For typical space environment spectra, several favorable comparisons with Monte Carlo calculations are made which have indicated that accuracy is not compromised at the expense of the computational speed.

  7. A cross-syndrome study of the development of holistic face recognition in children with autism, Down syndrome, and Williams syndrome.

    PubMed

    Annaz, Dagmara; Karmiloff-Smith, Annette; Johnson, Mark H; Thomas, Michael S C

    2009-04-01

    We report a cross-syndrome comparison of the development of holistic processing in face recognition in school-aged children with developmental disorders: autism, Down syndrome, and Williams syndrome. The autism group was split into two groups: one with high-functioning children and one with low-functioning children. The latter group has rarely been studied in this context. The four disorder groups were compared with typically developing children. Cross-sectional trajectory analyses were used to compare development in a modified version of Tanaka and Farah's part-whole task. Trajectories were constructed linking part-whole performance either to chronological age or to several measures of mental age (receptive vocabulary, visuospatial construction, and the Benton Facial Recognition Test). In addition to variable delays in onset and rate of development, we found an atypical profile in all disorder groups. These profiles were atypical in different ways, indicating multiple pathways to, and variable outcomes in, the development of face recognition. We discuss the implications for theories of face recognition in both atypical and typical development, including the idea that part-whole and rotation manipulations may tap different aspects of holistic and/or configural processing.

  8. Parent-child interaction over time in families of young children with borderline intellectual functioning.

    PubMed

    Fenning, Rachel M; Baker, Jason K; Baker, Bruce L; Crnic, Keith A

    2014-06-01

    A previous study suggested that mothers of 5-year-old children with borderline intellectual functioning displayed lower positive engagement with their children as compared with both mothers of typically developing children and mothers of children with significant developmental delays (Fenning, Baker, Baker, & Crnic, 2007). The current study integrated father data and followed these families over the subsequent 1-year period. Parent and child behavior were coded from naturalistic home observations at both waves. Results revealed that mothers of children with borderline intellectual functioning displayed a greater increase in negative-controlling parenting from child age 5 to 6 than did other mothers; fathers displayed more negative-controlling behavior in comparison to fathers of typically developing children. In addition, children with borderline intellectual functioning themselves exhibited a more significant escalation in difficult behavior than did typically developing children. Cross-lagged analyses for the sample as a whole indicated that maternal negative-controlling behavior predicted subsequent child difficulties, whereas negative paternal behavior was predicted by earlier child behavior. In conjunction with evidence from Fenning et al. (2007), these findings suggest a complex, dynamic, and systemic developmental pattern in the emotional behavior of families of children with borderline intellectual functioning. Implications and areas in need of additional research are discussed. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  9. Relativistic Shock Waves in Viscous Gluon Matter

    NASA Astrophysics Data System (ADS)

    Bouras, I.; Molnár, E.; Niemi, H.; Xu, Z.; El, A.; Fochler, O.; Greiner, C.; Rischke, D. H.

    2009-07-01

    We solve the relativistic Riemann problem in viscous gluon matter employing a microscopic parton cascade. We demonstrate the transition from ideal to viscous shock waves by varying the shear viscosity to entropy density ratio η/s from zero to infinity. We show that an η/s ratio larger than 0.2 prevents the development of well-defined shock waves on time scales typical for ultrarelativistic heavy-ion collisions. Comparisons with viscous hydrodynamic calculations confirm our findings.

  10. Behavioral and Socio-Emotional Functioning in Children with Selective Mutism: A Comparison with Anxious and Typically Developing Children across Multiple Informants

    ERIC Educational Resources Information Center

    Carbone, Diana; Schmidt, Louis A.; Cunningham, Charles C.; McHolm, Angela E.; Edison, Shannon; St. Pierre, Jeff; Boyle, Michael H.

    2010-01-01

    We examined differences among 158 children, 44 with selective mutism (SM; M = 8.2 years, SD = 3.4 years), 65 with mixed anxiety (MA; M = 8.9 years, SD = 3.2 years), and 49 community controls (M = 7.7 years, SD = 2.6 years) on primary caregiver, teacher, and child reports of behavioral and socio-emotional functioning. Children with SM were rated…

  11. Bed Prism Spectacles

    NASA Astrophysics Data System (ADS)

    Ribeiro, Jair Lúcio Prados

    2018-01-01

    We only became aware of the existence of bed prism spectacles when a student brought them to the classroom and asked us about how they work. The device proved to be a fertile source of curiosity among the students, and, to be properly understood, it required us to develop a comparison between reflection in a typical mirror and total internal reflection in a prism. In this article we explain the physics behind this unfamiliar device, supported by geometrical optics principles.

  12. Reading accuracy and speed of vowelized and unvowelized scripts among dyslexic readers of Hebrew: the road not taken.

    PubMed

    Schiff, Rachel; Katzir, Tami; Shoshan, Noa

    2013-07-01

    The present study examined the effects of orthographic transparency on reading ability of children with dyslexia in two Hebrew scripts. The study explored the reading accuracy and speed of vowelized and unvowelized Hebrew words of fourth-grade children with dyslexia. A comparison was made to typically developing readers of two age groups: a group matched by chronological age and a group of children who are 2 years younger, presumably at the end of the reading acquisition process. An additional purpose was to investigate the role of vowelization in the reading ability of unvowelized script among readers with dyslexia in an attempt to assess whether vowelization plays a mediating role for reading speed of unvowelized scripts. The present study found no significant differences in reading accuracy and speed between vowelized and unvowelized scripts among fourth-grade readers with dyslexia. The reading speed of fourth-graders with dyslexia was similar to typically developing second-graders for both the vowelized and unvowelized words. However, fourth-grade children with dyslexia performed lower than the typically developing second-graders in the reading accuracy of vowelized script. Furthermore, for readers with dyslexia, accuracy in reading both vowelized and unvowelized words mediated the reading speed of unvowelized scripts. These results may be a sign that Hebrew-speaking children with dyslexia have severe difficulties that prevent them from developing strategies for more efficient reading.

  13. Behavioral and emotional responses to interpersonal stress: A comparison of adolescents engaged in non-suicidal self-injury to adolescent suicide attempters.

    PubMed

    Kim, Kerri L; Cushman, Grace K; Weissman, Alexandra B; Puzia, Megan E; Wegbreit, Ezra; Tone, Erin B; Spirito, Anthony; Dickstein, Daniel P

    2015-08-30

    Prominent theoretical models and existing data implicate interpersonal factors in the development and maintenance of suicidal behavior and non-suicidal self-injury (NSSI). However, no known study has yet used computerized behavioral tasks to objectively assess responses to interpersonal conflict/collaboration among teens engaged in NSSI or having made a suicide attempt. The current study, therefore, compared interpersonal functioning indexed by the Prisoner's Dilemma (PD) task among three mutually exclusive groups, adolescents (ages 13-17): engaged in NSSI only without history of a suicide attempt (n=26); who made a suicide attempt without history of NSSI (n=26); and typically developing controls (n=26). Participants also completed the Interpersonal Sensitivity Measure to assess their general sensitivity to/awareness of others' behaviors and feelings. No significant between-group differences were found in PD task performance; however, compared to typically developing control participants and those who had made a suicide attempt, the NSSI group reported significantly more stress during the task. Additionally, NSSI participants rated themselves as more interpersonally sensitive compared to both attempters and typically developing controls. Given the lack of knowledge about whether these groups either differentially activate the same circuitry during stressful interpersonal interactions or instead rely on alternative, compensatory circuits, future work using event-related functional magnetic resonance imaging is warranted. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  14. Item Response Modeling of Paired Comparison and Ranking Data

    ERIC Educational Resources Information Center

    Maydeu-Olivares, Alberto; Brown, Anna

    2010-01-01

    The comparative format used in ranking and paired comparisons tasks can significantly reduce the impact of uniform response biases typically associated with rating scales. Thurstone's (1927, 1931) model provides a powerful framework for modeling comparative data such as paired comparisons and rankings. Although Thurstonian models are generally…

  15. Evaluation of Cirrus Cloud Simulations using ARM Data-Development of Case Study Data Set

    NASA Technical Reports Server (NTRS)

    Starr, David OC.; Demoz, Belay; Wang, Yansen; Lin, Ruei-Fong; Lare, Andrew; Mace, Jay; Poellot, Michael; Sassen, Kenneth; Brown, Philip

    2002-01-01

    Cloud-resolving models (CRMs) are being increasingly used to develop parametric treatments of clouds and related processes for use in global climate models (GCMs). CRMs represent the integrated knowledge of the physical processes acting to determine cloud system lifecycle and are well matched to typical observational data in terms of physical parameters/measurables and scale-resolved physical processes. Thus, they are suitable for direct comparison to field observations for model validation and improvement. The goal of this project is to improve state-of-the-art CRMs used for studies of cirrus clouds and to establish a relative calibration with GCMs through comparisons among CRMs, single column model (SCM) versions of the GCMs, and observations. The objective is to compare and evaluate a variety of CRMs and SCMs, under the auspices of the GEWEX Cloud Systems Study (GCSS) Working Group on Cirrus Cloud Systems (WG2), using ARM data acquired at the Southern Great Plains (SGP) site. This poster will report on progress in developing a suitable WG2 case study data set based on the September 26, 1996 ARM IOP case - the Hurricane Nora outflow case. Progress is assessing cloud and other environmental conditions will be described. Results of preliminary simulations using a regional cloud system model (MM5) and a CRM will be discussed. Focal science questions for the model comparison are strongly based on results of the idealized GCSS WG2 cirrus cloud model comparison projects (Idealized Cirrus Cloud Model Comparison Project and Cirrus Parcel Model Comparison Project), which will also be briefly summarized.

  16. Supporting Knowledge Integration in Chemistry with a Visualization-Enhanced Inquiry Unit

    NASA Astrophysics Data System (ADS)

    Chiu, Jennifer L.; Linn, Marcia C.

    2014-02-01

    This paper describes the design and impact of an inquiry-oriented online curriculum that takes advantage of dynamic molecular visualizations to improve students' understanding of chemical reactions. The visualization-enhanced unit uses research-based guidelines following the knowledge integration framework to help students develop coherent understanding by connecting and refining existing and new ideas. The inquiry unit supports students to develop connections among molecular, observable, and symbolic representations of chemical reactions. Design-based research included a pilot study, a study comparing the visualization-enhanced inquiry unit to typical instruction, and a course-long comparison study featuring a delayed posttest. Students participating in the visualization-enhanced unit outperformed students receiving typical instruction and further consolidated their understanding on the delayed posttest. Students who used the visualization-enhanced unit formed more connections among concepts than students with typical textbook and lecture-based instruction. Item analysis revealed the types of connections students made when studying the curriculum and suggested how these connections enabled students to consolidate their understanding as they continued in the chemistry course. Results demonstrate that visualization-enhanced inquiry designed for knowledge integration can improve connections between observable and atomic-level phenomena and serve students well as they study subsequent topics in chemistry.

  17. Applying an Integrative Framework of Executive Function to Preschoolers With Specific Language Impairment.

    PubMed

    Kapa, Leah L; Plante, Elena; Doubleday, Kevin

    2017-08-16

    The first goal of this research was to compare verbal and nonverbal executive function abilities between preschoolers with and without specific language impairment (SLI). The second goal was to assess the group differences on 4 executive function components in order to determine if the components may be hierarchically related as suggested within a developmental integrative framework of executive function. This study included 26 4- and 5-year-olds diagnosed with SLI and 26 typically developing age- and sex-matched peers. Participants were tested on verbal and nonverbal measures of sustained selective attention, working memory, inhibition, and shifting. The SLI group performed worse compared with typically developing children on both verbal and nonverbal measures of sustained selective attention and working memory, the verbal inhibition task, and the nonverbal shifting task. Comparisons of standardized group differences between executive function measures revealed a linear increase with the following order: working memory, inhibition, shifting, and sustained selective attention. The pattern of results suggests that preschoolers with SLI have deficits in executive functioning compared with typical peers, and deficits are not limited to verbal tasks. A significant linear relationship between group differences across executive function components supports the possibility of a hierarchical relationship between executive function skills.

  18. On Quantitative Comparative Research in Communication and Language Evolution

    PubMed Central

    Oller, D. Kimbrough; Griebel, Ulrike

    2014-01-01

    Quantitative comparison of human language and natural animal communication requires improved conceptualizations. We argue that an infrastructural approach to development and evolution incorporating an extended interpretation of the distinctions among illocution, perlocution, and meaning (Austin 1962; Oller and Griebel 2008) can help place the issues relevant to quantitative comparison in perspective. The approach can illuminate the controversy revolving around the notion of functional referentiality as applied to alarm calls, for example in the vervet monkey. We argue that referentiality offers a poor point of quantitative comparison across language and animal communication in the wild. Evidence shows that even newborn human cry could be deemed to show functional referentiality according to the criteria typically invoked by advocates of referentiality in animal communication. Exploring the essence of the idea of illocution, we illustrate an important realm of commonality among animal communication systems and human language, a commonality that opens the door to more productive, quantifiable comparisons. Finally, we delineate two examples of infrastructural communicative capabilities that should be particularly amenable to direct quantitative comparison across humans and our closest relatives. PMID:25285057

  19. On Quantitative Comparative Research in Communication and Language Evolution.

    PubMed

    Oller, D Kimbrough; Griebel, Ulrike

    2014-09-01

    Quantitative comparison of human language and natural animal communication requires improved conceptualizations. We argue that an infrastructural approach to development and evolution incorporating an extended interpretation of the distinctions among illocution, perlocution, and meaning (Austin 1962; Oller and Griebel 2008) can help place the issues relevant to quantitative comparison in perspective. The approach can illuminate the controversy revolving around the notion of functional referentiality as applied to alarm calls, for example in the vervet monkey. We argue that referentiality offers a poor point of quantitative comparison across language and animal communication in the wild. Evidence shows that even newborn human cry could be deemed to show functional referentiality according to the criteria typically invoked by advocates of referentiality in animal communication. Exploring the essence of the idea of illocution, we illustrate an important realm of commonality among animal communication systems and human language, a commonality that opens the door to more productive, quantifiable comparisons. Finally, we delineate two examples of infrastructural communicative capabilities that should be particularly amenable to direct quantitative comparison across humans and our closest relatives.

  20. Attainment of gross motor milestones in children with Down syndrome in Kosovo - developmental perspective.

    PubMed

    Beqaj, Samire; Jusaj, Njomza; Živković, Vujica

    2017-08-01

    Aim To investigate the age (in months) at which motor skills are developed in children with Down syndrome (DS), and compare it to the age of the development of the same skills in both, children with typical development (TD), and children with DS reported by four other studies. Methods Sixteen children (7 girls and 9 boys) were monthly assessed for the development of nineteen motor skills between 2008 and 2011. The mean ages when the skills were accomplished were presented using descriptive statistics. Independent T-samples test (significance < 0.05) was used to compare the mean developmental ages from our study with those seen in children with TD (Comparison 1) and also in children with DS reported by four other authors (Comparison 2a-2d). Results Children with DS developed at a significantly slower pace compared to children with TD (p=0.005). Generally, delay and variance of developmental age in children with DS increased chronologically with the complexity of the skills. No significant difference was found between developmental age in children from the present study and children with DS from other studies. Conclusion The rate of attainment of motor skills is delayed in children with DS in comparison to children with TD, however, the developmental sequence is the same. The delayed development is more prominent in more complex skills. Copyright© by the Medical Assotiation of Zenica-Doboj Canton.

  1. Comparison of Resource Requirements for a Wind Tunnel Test Designed with Conventional vs. Modern Design of Experiments Methods

    NASA Technical Reports Server (NTRS)

    DeLoach, Richard; Micol, John R.

    2011-01-01

    The factors that determine data volume requirements in a typical wind tunnel test are identified. It is suggested that productivity in wind tunnel testing can be enhanced by managing the inference error risk associated with evaluating residuals in a response surface modeling experiment. The relationship between minimum data volume requirements and the factors upon which they depend is described and certain simplifications to this relationship are realized when specific model adequacy criteria are adopted. The question of response model residual evaluation is treated and certain practical aspects of response surface modeling are considered, including inference subspace truncation. A wind tunnel test plan developed by using the Modern Design of Experiments illustrates the advantages of an early estimate of data volume requirements. Comparisons are made with a representative One Factor At a Time (OFAT) wind tunnel test matrix developed to evaluate a surface to air missile.

  2. Executive Function and Magnitude Skills in Preschool Children

    PubMed Central

    Prager, Emily O.; Sera, Maria D.; Carlson, Stephanie M.

    2016-01-01

    Executive Function (EF) has been highlighted as a potentially important factor for mathematical understanding. The relation has been well established in school-aged children but has been less explored at younger ages. The current study investigated the relation between EF and mathematics in preschool aged children. Participants were 142 typically developing 3- and 4-year-olds. Controlling for verbal ability, a significant positive correlation was found between EF and general math abilities in this age group. Importantly, we further examined this relation causally by varying the EF load on a magnitude comparison task. Results suggested a developmental pattern wherein 3-year-olds’ performance on the magnitude comparison task was worst when EF was taxed the most. Conversely, 4-year-olds performed well on the magnitude task despite varying EF demands, suggesting that EF might play a critical role in the development of math concepts. PMID:27082019

  3. Heave-pitch-roll analysis and testing of air cushion landing systems

    NASA Technical Reports Server (NTRS)

    Boghani, A. B.; Captain, K. M.; Wormley, D. N.

    1978-01-01

    The analytical tools (analysis and computer simulation) needed to explain and predict the dynamic operation of air cushion landing systems (ACLS) is described. The following tasks were performed: the development of improved analytical models for the fan and the trunk; formulation of a heave pitch roll analysis for the complete ACLS; development of a general purpose computer simulation to evaluate landing and taxi performance of an ACLS equipped aircraft; and the verification and refinement of the analysis by comparison with test data obtained through lab testing of a prototype cushion. Demonstration of simulation capabilities through typical landing and taxi simulation of an ACLS aircraft are given. Initial results show that fan dynamics have a major effect on system performance. Comparison with lab test data (zero forward speed) indicates that the analysis can predict most of the key static and dynamic parameters (pressure, deflection, acceleration, etc.) within a margin of a 10 to 25 percent.

  4. Tracking the effects of dyslexia in reading and spelling development: A longitudinal study of Greek readers.

    PubMed

    Diamanti, Vassiliki; Goulandris, Nata; Stuart, Morag; Campbell, Ruth; Protopapas, Athanassios

    2018-05-01

    In this study, we followed Greek children with and without dyslexia for 18 months, assessing them twice on a battery of phonological, reading, and spelling tasks, aiming to document the relative progress achieved and to uncover any specific effects of dyslexia in the development of reading and spelling beyond the longitudinal associations among variables that are observed in typical readers. A wide-ranging match was achieved between the dyslexic group and the younger reading-matched comparison group, enabling longitudinal comparisons on essentially identical initial performance profiles. Group differences were found in the development of tasks relying on phonological processing skill, such as phoneme deletion in pseudowords, pseudoword reading accuracy and time, as well as in graphemic spelling accuracy. The results confirm findings from cross-sectional studies of reading difficulty in the relatively transparent Greek orthography and are consistent with a phonological processing deficit underlying and reciprocally interacting with underdevelopment of reading and spelling skills in the impaired population. Copyright © 2018 John Wiley & Sons, Ltd.

  5. Development and Processing Improvement of Aerospace Aluminum Alloys-Development of AL-Cu-Mg-Ag Alloy (2139)

    NASA Technical Reports Server (NTRS)

    Cho, Alex; Lisagor, W. Barry; Bales, Thomas T.

    2007-01-01

    This final report supplement in presentation format describes a comprehensive multi-tasked contract study to continue the development of the silver bearing alloy now registered as aluminum alloy 2139 by the Aluminum Association. Two commercial scale ingots were processed into nominal plate gauges of two, four and six inches, and were extensively characterized in terms of metallurgical and crystallographic structure, and resulting mechanical properties. This report includes comparisons of the property combinations for this alloy and 2XXX and 7XXX alloys more widely used in high performance applications. Alloy 2139 shows dramatic improvement in all combinations of properties, moreover, the properties of this alloy are retained in all gauge thicknesses, contrary to typical reductions observed in thicker gauges of the other alloys in the comparison. The advancements achieved in this study are expected to result in rapid, widespread use of this alloy in a broad range of ground based, aircraft, and spacecraft applications.

  6. Programming Tools: Status, Evaluation, and Comparison

    NASA Technical Reports Server (NTRS)

    Cheng, Doreen Y.; Cooper, D. M. (Technical Monitor)

    1994-01-01

    In this tutorial I will first describe the characteristics of scientific applications and their developers, and describe the computing environment in a typical high-performance computing center. I will define the user requirements for tools that support application portability and present the difficulties to satisfy them. These form the basis of the evaluation and comparison of the tools. I will then describe the tools available in the market and the tools available in the public domain. Specifically, I will describe the tools for converting sequential programs, tools for developing portable new programs, tools for debugging and performance tuning, tools for partitioning and mapping, and tools for managing network of resources. I will introduce the main goals and approaches of the tools, and show main features of a few tools in each category. Meanwhile, I will compare tool usability for real-world application development and compare their different technological approaches. Finally, I will indicate the future directions of the tools in each category.

  7. Effect of internal versus external focus of attention on implicit motor learning in children with developmental coordination disorder.

    PubMed

    Jarus, Tal; Ghanouni, Parisa; Abel, Rachel L; Fomenoff, Shelby L; Lundberg, Jocelyn; Davidson, Stephanie; Caswell, Sarah; Bickerton, Laura; Zwicker, Jill G

    2015-02-01

    Children with developmental coordination disorder (DCD) struggle to learn new motor skills. It is unknown whether children with DCD learn motor skills more effectively with an external focus of attention (focusing on impact of movement on the environment) or an internal focus of attention (focusing on one's body movements) during implicit (unconscious) and explicit (conscious) motor learning. This paper aims to determine the trends of implicit motor learning in children with DCD, and how focus of attention influences motor learning in children with DCD in comparison with typically developing children. 25 children, aged 8-12, with (n=12) and without (n=13) DCD were randomly assigned to receive instructions that focused attention externally or internally while completing a computer tracking task during acquisition, retention, and transfer phases. The motor task involved tracking both repeated and random patterns, with the repeated pattern indicative of implicit learning. Children with DCD scored lower on the motor task in all three phases of the study, demonstrating poorer implicit learning. Furthermore, graphical data showed that for the children with DCD, there was no apparent difference between internal and external focus of attention during retention and transfer, while there was an advantage to the external focus of attention group for typically developing children. Children with DCD demonstrate less accuracy than typically developing children in learning a motor task. Also, the effect of focus of attention on motor performance is different in children with DCD versus their typically developing counterparts during the three phases of motor learning. Results may inform clinicians how to facilitate motor learning in children with DCD by incorporating explicit learning with either internal or external focus of attention within interventions. Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. The profile of social functioning in children with Down syndrome.

    PubMed

    Næss, Kari-Anne B; Nygaard, Egil; Ostad, Johanne; Dolva, Anne-Stine; Lyster, Solveig-Alma Halaas

    2017-06-01

    Practitioners and researchers have asserted for decades that social functioning is a strength in children with Down syndrome (DS). Nevertheless, some studies have concluded that children with DS may be at greater risk of impaired social functioning compared to typically developing controls. This cross-sectional study explores the profile of social functioning (social capabilities and social problems) in six-year-old children with DS, compares it with that of typically developing children and reveals possible differences in predictors between groups. Parental reports and clinical tests were utilized. The children with DS had generally weaker social capabilities compared to nonverbal mental age-matched controls, but no significant differences were found for social interactive play, community functioning and prosocial behaviour. No significant differences in predictors for social capabilities between the groups were found. The children with DS had more social problems than the typically developing controls with a similar chronological age and those with a similar nonverbal mental age, but no significant differences in emotional symptoms were found between the children with DS and either comparison group. Vocabulary was a more important predictor of social problems in the children with DS than in the typically developing control groups. Interventions for children with DS should strongly focus on integrating vocabulary skills and social functioning starting at an early age. Implications for Rehabilitation Children with Down syndrome need help and support in social functioning. Systematic training to optimize social capabilities and to prevent social problems should be prioritized. Structured and explicit learning of words important for social interaction with peers and for conflict solutions should be emphasized. Integrated interventions focusing on social functioning and vocabulary should begin in preschool to prepare children for participation in mainstream education.

  9. Dietary intake and parents' perception of mealtime behaviors in preschool-age children with autism spectrum disorder and in typically developing children.

    PubMed

    Lockner, Donna W; Crowe, Terry K; Skipper, Betty J

    2008-08-01

    Parents of children with autism spectrum disorder (ASD) frequently report that their children have selective eating behaviors and refuse many foods, which could result in inadequate nutrient intake. This preliminary cross-sectional descriptive study investigated dietary intake and parents' reported perception of food behaviors of 20 3- to 5-year-old children with ASD. Twenty typically developing children matched for sex, age, and ethnicity were also studied as a case-control comparison. Nutrient intake determined from 3-day food records was adjusted for day-to-day variation to determine the estimate of usual intake distribution for the two groups. This distribution was compared with the Estimated Average Requirement or Adequate Intake recommendations. The reported food behaviors and use of vitamin or mineral supplements were compared for matched pairs using the exact McNemar test. Nutrient intake was similar for both groups of children, with the majority of children consuming more than the recommended amounts for most nutrients. Nutrients least likely to be consumed in recommended amounts were vitamin A, vitamin E, fiber, and calcium. Children with ASD were more likely to consume vitamin/mineral supplements than typically developing children. Compared with parents of typically developing children, parents of children with ASD were more likely to report that their children were picky eaters and resisted trying new foods, and they were less likely to describe their children as healthy eaters or that they eat a variety of foods. Despite the similar and generally adequate nutrient intake for the 40 children in this study, parents of children with ASD had more negative perceptions of their children's dietary behaviors.

  10. Comparative study on the efficiency of some optical methods for artwork diagnostics

    NASA Astrophysics Data System (ADS)

    Schirripa Spagnolo, Giuseppe; Ambrosini, Dario; Paoletti, Domenica

    2001-10-01

    Scientific investigation methods are founding their place besides the stylistic-historical study methods in art research works. In particular, optical techniques, transferred from other fields or developed ad hoc, can make a strong contribution to the safeguarding and exploitation of cultural heritage. This paper describes the use of different optical techniques, such as holographic interferometry, decorrelation, shearography and ESPI, in the diagnostics of works of art. A comparison between different methods is obtained by performing tests on specially designed models, prepared using typical techniques and materials. Inside the model structure, a number of defects of known types, form and extension are inserted. The different features of each technique are outlined and a comparison with IR thermography is also carried out.

  11. The Persian version of auditory word discrimination test (P-AWDT) for children: Development, validity, and reliability.

    PubMed

    Hashemi, Nassim; Ghorbani, Ali; Soleymani, Zahra; Kamali, Mohmmad; Ahmadi, Zohreh Ziatabar; Mahmoudian, Saeid

    2018-07-01

    Auditory discrimination of speech sounds is an important perceptual ability and a precursor to the acquisition of language. Auditory information is at least partially necessary for the acquisition and organization of phonological rules. There are few standardized behavioral tests to evaluate phonemic distinctive features in children with or without speech and language disorders. The main objective of the present study was the development, validity, and reliability of the Persian version of auditory word discrimination test (P-AWDT) for 4-8-year-old children. A total of 120 typical children and 40 children with speech sound disorder (SSD) participated in the present study. The test comprised of 160 monosyllabic paired-words distributed in the Forms A-1 and the Form A-2 for the initial consonants (80 words) and the Forms B-1 and the Form B-2 for the final consonants (80 words). Moreover, the discrimination of vowels was randomly included in all forms. Content validity was calculated and 50 children repeated the test twice with two weeks of interval (test-retest reliability). Further analysis was also implemented including validity, intraclass correlation coefficient (ICC), Cronbach's alpha (internal consistency), age groups, and gender. The content validity index (CVI) and the test-retest reliability of the P-AWDT were achieved 63%-86% and 81%-96%, respectively. Moreover, the total Cronbach's alpha for the internal consistency was estimated relatively high (0.93). Comparison of the mean scores of the P-AWDT in the typical children and the children with SSD revealed a significant difference. The results revealed that the group with SSD had greater severity of deficit than the typical group in auditory word discrimination. In addition, the difference between the age groups was statistically significant, especially in 4-4.11-year-old children. The performance of the two gender groups was relatively same. The comparison of the P-AWDT scores between the typical children and the children with SSD demonstrated differences in the capabilities of auditory phonological discrimination in both initial and final positions. It supposed that the P-AWDT meets the appropriate validity and reliability criteria. The P-AWDT test can be utilized to measure the distinctive features of phonemes, the auditory discrimination of initial and final consonants and middle vowels of words in 4-8-year-old typical children and children with SSD. Copyright © 2018. Published by Elsevier B.V.

  12. A comparison of FE beam and continuum elements for typical nitinol stent geometries

    NASA Astrophysics Data System (ADS)

    Ballew, Wesley; Seelecke, Stefan

    2009-03-01

    With interest in improved efficiency and a more complete description of the SMA material, this paper compares finite element (FE) simulations of typical stent geometries using two different constitutive models and two different element types. Typically, continuum elements are used for the simulation of stents, for example the commercial FE software ANSYS offers a continuum element based on Auricchio's SMA model. Almost every stent geometry, however, is made up of long and slender components and can be modeled more efficiently, in the computational sense, with beam elements. Using the ANSYS user programmable material feature, we implement the free energy based SMA model developed by Mueller and Seelecke into the ANSYS beam element 188. Convergence behavior for both, beam and continuum formulations, is studied in terms of element and layer number, respectively. This is systematically illustrated first for the case of a straight cantilever beam under end loading, and subsequently for a section of a z-bend wire, a typical stent sub-geometry. It is shown that the computation times for the beam element are reduced to only one third of those of the continuum element, while both formulations display a comparable force/displacement response.

  13. ENVIRONMENTAL COMPARISON METRICS FOR LIFE CYCLE IMPACT ASSESSMENT AND PROCESS DESIGN

    EPA Science Inventory

    Metrics (potentials, potency factors, equivalency factors or characterization factors) are available to support the environmental comparison of alternatives in application domains like proces design and product life-cycle assessment (LCA). These metrics typically provide relative...

  14. Reduced chromatic discrimination in children with autism spectrum disorders.

    PubMed

    Franklin, Anna; Sowden, Paul; Notman, Leslie; Gonzalez-Dixon, Melissa; West, Dorotea; Alexander, Iona; Loveday, Stephen; White, Alex

    2010-01-01

    Atypical perception in Autism Spectrum Disorders (ASD) is well documented (Dakin & Frith, 2005). However, relatively little is known about colour perception in ASD. Less accurate performance on certain colour tasks has led some to argue that chromatic discrimination is reduced in ASD relative to typical development (Franklin, Sowden, Burley, Notman & Alder, 2008). The current investigation assessed chromatic discrimination in children with high-functioning autism (HFA) and typically developing (TD) children matched on age and non-verbal cognitive ability, using the Farnsworth-Munsell 100 hue test (Experiment 1) and a threshold discrimination task (Experiment 2). In Experiment 1, more errors on the chromatic discrimination task were made by the HFA than the TD group. Comparison with test norms revealed that performance for the HFA group was at a similar level to typically developing children around 3 years younger. In Experiment 2, chromatic thresholds were elevated for the HFA group relative to the TD group. For both experiments, reduced chromatic discrimination in ASD was due to a general reduction in chromatic sensitivity rather than a specific difficulty with either red-green or blue-yellow subsystems of colour vision. The absence of group differences on control tasks ruled out an explanation in terms of general task ability rather than chromatic sensitivity. Theories to account for the reduction in chromatic discrimination in HFA are discussed, and findings are related to cortical models of perceptual processing in ASD.

  15. Comparing service use and costs among adolescents with autism spectrum disorders, special needs and typical development.

    PubMed

    Barrett, Barbara; Mosweu, Iris; Jones, Catherine Rg; Charman, Tony; Baird, Gillian; Simonoff, Emily; Pickles, Andrew; Happé, Francesca; Byford, Sarah

    2015-07-01

    Autism spectrum disorder is a complex condition that requires specialised care. Knowledge of the costs of autism spectrum disorder, especially in comparison with other conditions, may be useful to galvanise policymakers and leverage investment in education and intervention to mitigate aspects of autism spectrum disorder that negatively impact individuals with the disorder and their families. This article describes the services and associated costs for four groups of individuals: adolescents with autistic disorder, adolescents with other autism spectrum disorders, adolescents with other special educational needs and typically developing adolescents using data from a large, well-characterised cohort assessed as part of the UK Special Needs and Autism Project at the age of 12 years. Average total costs per participant over 6 months were highest in the autistic disorder group (£11,029), followed by the special educational needs group (£9268), the broader autism spectrum disorder group (£8968) and the typically developing group (£2954). Specialised day or residential schooling accounted for the vast majority of costs. In regression analysis, lower age and lower adaptive functioning were associated with higher costs in the groups with an autism spectrum disorder. Sex, ethnicity, number of International Classification of Diseases (10th revision) symptoms, autism spectrum disorder symptom scores and levels of mental health difficulties were not associated with cost. © The Author(s) 2014.

  16. White Matter Integrity and Pictorial Reasoning in High-Functioning Children with Autism

    PubMed Central

    Sahyoun, Chérif P.; Belliveau, John W.; Mody, Maria

    2010-01-01

    The current study investigated the neurobiological role of white matter in visuospatial versus linguistic processing abilities in autism using diffusion tensor imaging. We examined differences in white matter integrity between high-functioning children with autism (HFA) and typically developing controls (CTRL), in relation to the groups’ response times (RT) on a pictorial reasoning task under three conditions: visuospatial, V, semantic, S, and V+S, a hybrid condition allowing language use to facilitate visuospatial transformations. Diffusion-weighted images were collected from HFA and CTRL participants, matched on age and IQ, and significance maps were computed for group differences in fractional anisotropy (FA) and in RT-FA association for each condition. Typically developing children showed increased FA within frontal white matter and the superior longitudinal fasciculus (SLF). HFA showed increased FA within peripheral white matter, including the ventral temporal lobe. Additionally, RT-FA relationships in the semantic condition (S) implicated white matter near the STG and in the SLF within the temporal and frontal lobes to a greater extent in CTRL. Performance in visuospatial reasoning (V, V+S), in comparison, was related to peripheral parietal and superior precentral white matter in HFA, but to the SLF, callosal, and frontal white matter in CTRL. Our results appear to support a preferential use of linguistically-mediated pathways in reasoning by typically-developing children, whereas autistic cognition may rely more on visuospatial processing networks. PMID:20542370

  17. Assessing disordered thoughts in preschoolers with dysregulated mood.

    PubMed

    Hutchison, Amanda K; Beresford, Carol; Robinson, Joann; Ross, Randal G

    2010-10-01

    There is rising interest in identifying precursors to bipolar disorder symptoms, including thought disorder. Thought disorder is identified in adults through self-report and in school-aged children through parent report and child story-telling. This study is an exploration to determine if preschoolers with mood dysregulation have evidence of disordered thoughts using a story-stem completion method. Participants included two groups of 3.5-6 year-old children: 20 with mood dysregulation including manic symptoms and 11 typically developing comparison children. Children were administered story completion narratives including one story where the child character accidentally cuts him/herself while pretending to cook. The children were asked to complete the stories and their responses were analyzed for atypical themes consistent with disordered thoughts such as violence or bizarreness outside of the story or props coming to life. Thirty-five percentage of symptomatic preschoolers versus 0% of typically developing preschoolers ascribed independent actions to inanimate props (p = 0.03). Eighty percentage of symptomatic preschoolers versus 9% of typically developing preschoolers utilized props in a violent or bizarre manner outside the central story (p < 0.001). Preschool children with symptoms of dysregulated mood express themes related to the unusual use of story props which may indicate disordered thoughts. This preschool expression of dysregulated mood appears similar to and possibly continuous with school-age and adult versions of bipolar disorder.

  18. The role of executive functions in social impairment in Autism Spectrum Disorder.

    PubMed

    Leung, Rachel C; Vogan, Vanessa M; Powell, Tamara L; Anagnostou, Evdokia; Taylor, Margot J

    2016-01-01

    Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by socio-communicative impairments. Executive dysfunction may explain some key characteristics of ASD, both social and nonsocial hallmarks. Limited research exists exploring the relations between executive function and social impairment in ASD and few studies have used a comparison control group. Thus, the objective of the present study was to investigate the relations between executive functioning using the Behavioral Rating Inventory of Executive Functioning (BRIEF), social impairment as measured by the Social Responsiveness Scale (SRS), and overall autistic symptomology as measured by the Autism Diagnostic Observation Schedule (ADOS) in children and adolescents with and without ASD. Seventy children and adolescents diagnosed with ASD and 71 typically developing controls were included in this study. Findings showed that behavioral regulation executive processes (i.e., inhibition, shifting, and emotional control) predicted social function in all children. However, metacognitive executive processes (i.e., initiation, working memory, planning, organization, and monitoring) predicted social function only in children with ASD and not in typically developing children. Our findings suggest a distinct metacognitive executive function-social symptom link in ASD that is not present in the typical population. Understanding components of executive functioning that contribute to the autistic symptomology, particularly in the socio-communicative domain, is crucial for developing effective interventions that target key executive processes as well as underlying behavioral symptoms.

  19. Linguistic and pragmatic aspects of narration in Finnish typically developing children and children with specific language impairment.

    PubMed

    Mäkinen, Leena; Loukusa, Soile; Laukkanen, Päivi; Leinonen, Eeva; Kunnari, Sari

    2014-06-01

    This study investigates narratives of Finnish children with specific language impairment (SLI) from linguistic and pragmatic perspectives, in order to get a comprehensive overview of these children's narrative abilities. Nineteen children with SLI (mean age 6;1 years) and 19 typically developing age-matched children participated in the study. Their picture-elicited narrations were analysed for linguistic productivity and complexity, grammatical and referential accuracy, event content, the use of mental state expressions and narrative comprehension. Children with SLI showed difficulties in every aspect of narration in comparison to their peers. Only one measure of productivity, the number of communication units, did not reach statistical significance. Not only was linguistic structure fragile but also pragmatic aspects of storytelling (referencing, event content, mental state expressions and inferencing) were demanding for children with SLI. Results suggest that pragmatic aspects of narration should be taken into account more often when assessing narrative abilities of children with SLI.

  20. How are they doing? Listening as fathers of children with autism spectrum disorder compare themselves to fathers of children who are typically developing.

    PubMed

    Cheuk, Samantha; Lashewicz, Bonnie

    2016-04-01

    The growing prevalence of autism spectrum disorder is accompanied by ongoing efforts to understand and support parents in the face of challenges related to their child's autism spectrum disorder. Although fathers are increasingly hands-on in raising children, research focus on parenting children with autism spectrum disorder continues to be skewed toward experiences of mothers. Our purpose in this article is to contribute understandings of how fathers of children with autism spectrum disorder perceive themselves to be managing, and we undertake this by examining comparisons fathers of children with autism spectrum disorder make between their parenting experiences and experiences of fathers of typically developing children. A purposive sample of 28 fathers of children (aged 2-13 years) with autism spectrum disorder living in an urban center in Western Canada participated in in-depth interviews about their parenting successes and challenges. We found fathers speak of universal fathering experiences yet articulate their own sense of loss and efforts to come to terms with unanticipated demands associated with autism spectrum disorder. Fathers of children with autism spectrum disorder feel "pangs of jealousy" toward fathers of typically developing children, yet they are keenly attentive to their own child's development and convey a sense of gratitude for their child's capabilities and personality amidst an appreciation for trials and triumphs of fathering in general and fathering a child with autism spectrum disorder in particular. © The Author(s) 2015.

  1. Task- and age-dependent effects of visual stimulus properties on children's explicit numerosity judgments.

    PubMed

    Defever, Emmy; Reynvoet, Bert; Gebuis, Titia

    2013-10-01

    Researchers investigating numerosity processing manipulate the visual stimulus properties (e.g., surface). This is done to control for the confound between numerosity and its visual properties and should allow the examination of pure number processes. Nevertheless, several studies have shown that, despite different visual controls, visual cues remained to exert their influence on numerosity judgments. This study, therefore, investigated whether the impact of the visual stimulus manipulations on numerosity judgments is dependent on the task at hand (comparison task vs. same-different task) and whether this impact changes throughout development. In addition, we examined whether the influence of visual stimulus manipulations on numerosity judgments plays a role in the relation between performance on numerosity tasks and mathematics achievement. Our findings confirmed that the visual stimulus manipulations affect numerosity judgments; more important, we found that these influences changed with increasing age and differed between the comparison and the same-different tasks. Consequently, direct comparisons between numerosity studies using different tasks and age groups are difficult. No meaningful relationship between the performance on the comparison and same-different tasks and mathematics achievement was found in typically developing children, nor did we find consistent differences between children with and without mathematical learning disability (MLD). Copyright © 2013 Elsevier Inc. All rights reserved.

  2. Simulation and performance of brushless dc motor actuators

    NASA Astrophysics Data System (ADS)

    Gerba, A., Jr.

    1985-12-01

    The simulation model for a Brushless D.C. Motor and the associated commutation power conditioner transistor model are presented. The necessary conditions for maximum power output while operating at steady-state speed and sinusoidally distributed air-gap flux are developed. Comparison of simulated model with the measured performance of a typical motor are done both on time response waveforms and on average performance characteristics. These preliminary results indicate good agreement. Plans for model improvement and testing of a motor-driven positioning device for model evaluation are outlined.

  3. The Revision Decision: Is Change Always Good? A Comparison of CELF-R and CELF-3 Test Scores in Children with Language Impairment, Focal Brain Damage, and Typical Development

    ERIC Educational Resources Information Center

    Ballantyne, Angela O.; Spilkin, Amy M.; Trauner, Doris A.

    2007-01-01

    Purpose: The Clinical Evaluation of Language Fundamentals (CELF) is a widely used, comprehensive test battery that assesses language in school-age children and adolescents. The CELF-R (E. Semel, E. H. Wiig, & W. Secord, 1987) was updated to the CELF-3 (E. Semel, E. H. Wiig, & W. A. Secord, 1995) in 1995. The goal of the present study was to…

  4. Whole-Range Assessment: A Simple Method for Analysing Allelopathic Dose-Response Data

    PubMed Central

    An, Min; Pratley, J. E.; Haig, T.; Liu, D.L.

    2005-01-01

    Based on the typical biological responses of an organism to allelochemicals (hormesis), concepts of whole-range assessment and inhibition index were developed for improved analysis of allelopathic data. Examples of their application are presented using data drawn from the literature. The method is concise and comprehensive, and makes data grouping and multiple comparisons simple, logical, and possible. It improves data interpretation, enhances research outcomes, and is a statistically efficient summary of the plant response profiles. PMID:19330165

  5. Dynamic Simulation of AN Helium Refrigerator

    NASA Astrophysics Data System (ADS)

    Deschildre, C.; Barraud, A.; Bonnay, P.; Briend, P.; Girard, A.; Poncet, J. M.; Roussel, P.; Sequeira, S. E.

    2008-03-01

    A dynamic simulation of a large scale existing refrigerator has been performed using the software Aspen Hysys®. The model comprises the typical equipments of a cryogenic system: heat exchangers, expanders, helium phase separators and cold compressors. It represents the 400 W @ 1.8 K Test Facility located at CEA—Grenoble. This paper describes the model development and shows the possibilities and limitations of the dynamic module of Aspen Hysys®. Then, comparison between simulation results and experimental data are presented; the simulation of cooldown process was also performed.

  6. Comparisons of the Factor Structure and Measurement Invariance of the Spence Children's Anxiety Scale-Parent Version in Children with Autism Spectrum Disorder and Typically Developing Anxious Children

    ERIC Educational Resources Information Center

    Glod, Magdalena; Creswell, Cathy; Waite, Polly; Jamieson, Ruth; McConachie, Helen; South, Mikle Don; Rodgers, Jacqui

    2017-01-01

    The Spence Children's Anxiety Scale-Parent version (SCAS-P) is often used to assess anxiety in children with autism spectrum disorder (ASD), however, little is known about the validity of the tool in this population. The aim of this study was to determine whether the SCAS-P has the same factorial validity in a sample of young people with ASD (n =…

  7. Fiber Amplifier Report for NEPP 2008

    NASA Technical Reports Server (NTRS)

    Thomes, Joe; Ott, Melanie; LaRocca, Frank; Chuska, Rick; Switzer, Rob

    2008-01-01

    Ongoing qualification activities of LiNbO3 modulators. Passive (unpumped) radiation testing of Er-, Yb-, and Er/Yb-doped fibers: a) Yb-doped fibers exhibit higher radiation resistance than Er-doped fibers; b) Er/Yb co-doped fibers exhibit largest radiation resistance. Active (pumped) radiation testing of Yb-doped fibers conducted at NASA GSFC: a) Typical decay behavior observed; b) No comparison could be made to other fibers due to problems with test setup. Development of new high power fiber terminations.

  8. Exploring the cognitive features in children with autism spectrum disorder, their co-twins, and typically developing children within a population-based sample.

    PubMed

    Brunsdon, Victoria E A; Colvert, Emma; Ames, Catherine; Garnett, Tracy; Gillan, Nicola; Hallett, Victoria; Lietz, Stephanie; Woodhouse, Emma; Bolton, Patrick; Happé, Francesca

    2015-08-01

    The behavioural symptoms of autism spectrum disorder (ASD) are thought to reflect underlying cognitive deficits/differences. The findings in the literature are somewhat mixed regarding the cognitive features of ASD. This study attempted to address this issue by investigating a range of cognitive deficits and the prevalence of multiple cognitive atypicalities in a large population-based sample comprising children with ASD, their unaffected co-twins, and typically developing comparison children. Participants included families from the Twins Early Development Study (TEDS) where one or both children met diagnostic criteria for ASD. Overall, 181 adolescents with a diagnosis of ASD and 73 unaffected co-twins were included, plus an additional 160 comparison control participants. An extensive cognitive battery was administered to measure IQ, central coherence, executive function, and theory of mind ability. Differences between groups (ASD, co-twin, control) are reported on tasks assessing theory of mind, executive function, and central coherence. The ASD group performed atypically in significantly more cognitive tasks than the unaffected co-twin and control groups. Nearly a third of the ASD group presented with multiple cognitive atypicalities. Multiple cognitive atypicalities appear to be a characteristic, but not universal feature, of ASD. Further work is needed to investigate whether specific cognitive atypicalities, either alone or together, are related to specific behaviours characteristic of ASD. © 2014 The Authors. Journal of Child Psychology and Psychiatry published by John Wiley & Sons Ltd on behalf of Association for Child and Adolescent Mental Health.

  9. Space propulsion systems. Present performance limits and application and development trends

    NASA Technical Reports Server (NTRS)

    Buehler, R. D.; Lo, R. E.

    1981-01-01

    Typical spaceflight programs and their propulsion requirements as a comparison for possible propulsion systems are summarized. Chemical propulsion systems, solar, nuclear, or even laser propelled rockets with electrical or direct thermal fuel acceleration, nonrockets with air breathing devices and solar cells are considered. The chemical launch vehicles have similar technical characteristics and transportation costs. A possible improvement of payload by using air breathing lower stages is discussed. The electrical energy supply installations which give performance limits of electrical propulsion and the electrostatic ion propulsion systems are described. The development possibilities of thermal, magnetic, and electrostatic rocket engines and the state of development of the nuclear thermal rocket and propulsion concepts are addressed.

  10. An interactive environment for the analysis of large Earth observation and model data sets

    NASA Technical Reports Server (NTRS)

    Bowman, Kenneth P.; Walsh, John E.; Wilhelmson, Robert B.

    1993-01-01

    We propose to develop an interactive environment for the analysis of large Earth science observation and model data sets. We will use a standard scientific data storage format and a large capacity (greater than 20 GB) optical disk system for data management; develop libraries for coordinate transformation and regridding of data sets; modify the NCSA X Image and X DataSlice software for typical Earth observation data sets by including map transformations and missing data handling; develop analysis tools for common mathematical and statistical operations; integrate the components described above into a system for the analysis and comparison of observations and model results; and distribute software and documentation to the scientific community.

  11. An interactive environment for the analysis of large Earth observation and model data sets

    NASA Technical Reports Server (NTRS)

    Bowman, Kenneth P.; Walsh, John E.; Wilhelmson, Robert B.

    1992-01-01

    We propose to develop an interactive environment for the analysis of large Earth science observation and model data sets. We will use a standard scientific data storage format and a large capacity (greater than 20 GB) optical disk system for data management; develop libraries for coordinate transformation and regridding of data sets; modify the NCSA X Image and X Data Slice software for typical Earth observation data sets by including map transformations and missing data handling; develop analysis tools for common mathematical and statistical operations; integrate the components described above into a system for the analysis and comparison of observations and model results; and distribute software and documentation to the scientific community.

  12. In Pursuit of Neurophenotypes: The Consequences of Having Autism and a Big Brain

    PubMed Central

    Amaral, David G.; Li, Deana; Libero, Lauren; Solomon, Marjorie; Van de Water, Judy; Mastergeorge, Ann; Naigles, Letitia; Rogers, Sally; Nordahl, Christine Wu

    2017-01-01

    A consensus has emerged that despite common core features, autism spectrum disorder (ASD) has multiple etiologies and various genetic and biological characteristics. The fact that there are likely to be subtypes of ASD has complicated attempts to develop effective therapies. The UC Davis MIND Institute Autism Phenome Project is a longitudinal, multidisciplinary analysis of children with autism and age-matched typically developing controls; nearly 400 families are participating in this study. The overarching goal is to gather sufficient biological, medical, and behavioral data to allow definition of clinically meaningful subtypes of ASD. One reasonable hypothesis is that different subtypes of autism will demonstrate different patterns of altered brain organization or development i.e., different neurophenotypes. In this Commentary, we discuss one neurophenotype that is defined by megalencephaly, or having brain size that is large and disproportionate to body size. We have found that 15% of the boys with autism demonstrate this neurophenotype, though it is far less common in girls. We review behavioral and medical characteristics of the large-brained group of boys with autism in comparison to those with typically sized brains. While brain size in typically developing individuals is positively correlated with cognitive function, the children with autism and larger brains have more severe disabilities and poorer prognosis. This research indicates that phenotyping in autism, like genotyping, requires a very substantial cohort of subjects. Moreover, since brain and behavior relationships may emerge at different times during development, this effort highlights the need for longitudinal analyses to carry out meaningful phenotyping. PMID:28239961

  13. A Comparison of the Gestural Communication of Apes and Human Infants.

    ERIC Educational Resources Information Center

    Tomasello, Michael; Camaioni, Luigia

    1997-01-01

    Compared the gestures of typical human infants, children with autism, chimpanzees, and human-raised chimpanzees. Typical infants differed from the other groups in their use of: triadic gestures directing another's attention to an outside entity; declarative gestures; and imitation in acquiring some gestures. These differences derive from an…

  14. Swedish Upper Secondary Students' Perspectives on the Typical Mathematics Lesson

    ERIC Educational Resources Information Center

    Andrews, Paul; Larson, Niclas

    2017-01-01

    This paper presents a group interview study of Swedish upper secondary students' perspectives on the typical mathematics lesson. Students, from four demographically different schools, constructed a collective synthesis of their many years' experience of mathematics classrooms. Transcriptions were subjected to a constant comparison analysis, which…

  15. [Features of sexual development of adolescent boys in cities of Caspian region of the Republic of Kazakhstan].

    PubMed

    Kurmangaliev, O M; Gumarova, Zh Zh; Zasorin, B V

    2014-01-01

    The complex estimation of parameters of the sexual development of adolescent boys aged 14-16 years had been done in cities of Aktay and Atyrau, in Caspian region of Western Kazakhstan. Adolescent boys in cities of Caspian region of the Republic of Kazakhstan were found to have tendency to the delayed puberty according to Tanner score. Retarded sexual development is manifested by the some retardation in growth of genitals and escutcheon, in comparison with their peers from control group. The absence of differences in general physical development, as evidenced by anthropometry data, does not exclude the specific (elective) character of the impact of urbanogenic factors on growing male body, which is typical impact of hard metals salts.

  16. Quality of life in newly diagnosed children with specific learning disabilities (SpLD) and differences from typically developing children: a study of child and parent reports.

    PubMed

    Ginieri-Coccossis, M; Rotsika, V; Skevington, S; Papaevangelou, S; Malliori, M; Tomaras, V; Kokkevi, A

    2013-07-01

    Research on quality of life (QoL) of school children with specific learning disabilities (SpLD) and their parents is scarce. The present study explores QoL deficits in newly diagnosed children with SpLD and their parents, in comparison to a similar age group of typically developing children. Possible associations between parental and child QoL were statistically explored in both groups of children. 70 newly diagnosed children with SpLD [International Classification of Diseases-10 (ICD-10) criteria] (38 boys, 32 girls, mean age 10.1 years) and a control group of 69 typically developing children of the same age (40 boys, 29 girls, mean age 10.6 years) were recruited. Children were of normal intelligence quotient, attending mainstream schools. Their parents were also recruited so a child's scores could be associated with corresponding parental scores (mother or father). Children's QoL was assessed by the German questionnaire for measuring quality of life in children and adolescents (KINDL(R) ) questionnaire and parental QoL by World Health Organization Quality of Life brief questionnaire (WHOQOL-BREF) of the World Health Organization. Children with SpLD in comparison to typically developing children reported according to the KINDL(R) measurement poorer emotional well-being, lower self-esteem and satisfaction in their relationships with family and friends. Surprisingly, school functioning was not reported by these children as an area of concern. Parents of children with SpLD indicated experiencing lower satisfaction in the WHOQOL-BREF domains of social relationships and environment. Correlational and regression analysis with parental-child QoL scores provided evidence that in the SpLD group, parental scores on WHOQOL-BREF social relationships and psychological health domains could be predictors of the child's emotional well-being, satisfaction with family, friends and school functioning. Stepwise regression analysis verified the effect of parents' WHOQOL-BREF social relationships domain on several dimensions of children's KINDL(R) QoL.   The results may suggest certain significant effects of the SpLD condition on newly diagnosed children's QoL. Emotional and social deficits seem to be experienced by this cohort of children and their parents. Investigation into the possible interrelationships between parental and child QoL seems to indicate that parental social wellbeing may to a certain extend influence some dimensions of the child's QoL. The findings are useful for policy making and specialized interventions for children with SpLD and their families. © 2012 John Wiley & Sons Ltd.

  17. Study on the three-station typical network deployments of workspace Measurement and Positioning System

    NASA Astrophysics Data System (ADS)

    Xiong, Zhi; Zhu, J. G.; Xue, B.; Ye, Sh. H.; Xiong, Y.

    2013-10-01

    As a novel network coordinate measurement system based on multi-directional positioning, workspace Measurement and Positioning System (wMPS) has outstanding advantages of good parallelism, wide measurement range and high measurement accuracy, which makes it to be the research hotspots and important development direction in the field of large-scale measurement. Since station deployment has a significant impact on the measurement range and accuracy, and also restricts the use-cost, the optimization method of station deployment was researched in this paper. Firstly, positioning error model was established. Then focusing on the small network consisted of three stations, the typical deployments and error distribution characteristics were studied. Finally, through measuring the simulated fuselage using typical deployments at the industrial spot and comparing the results with Laser Tracker, some conclusions are obtained. The comparison results show that under existing prototype conditions, I_3 typical deployment of which three stations are distributed in a straight line has an average error of 0.30 mm and the maximum error is 0.50 mm in the range of 12 m. Meanwhile, C_3 typical deployment of which three stations are uniformly distributed in the half-circumference of an circle has an average error of 0.17 mm and the maximum error is 0.28 mm. Obviously, C_3 typical deployment has a higher control effect on precision than I_3 type. The research work provides effective theoretical support for global measurement network optimization in the future work.

  18. Adaptation of object descriptions to a partner under increasing communicative demands: a comparison of children with and without autism.

    PubMed

    Nadig, Aparna; Vivanti, Giacomo; Ozonoff, Sally

    2009-12-01

    This study compared the object descriptions of school-age children with high-functioning autism (HFA) with those of a matched group of typically developing children. Descriptions were elicited in a referential communication task where shared information was manipulated, and in a guessing game where clues had to be provided about the identity of an object that was hidden from the addressee. Across these tasks, increasingly complex levels of audience design were assessed: (1) the ability to give adequate descriptions from one's own perspective, (2) the ability to adjust descriptions to an addressee's perspective when this differs from one's own, and (3) the ability to provide indirect yet identifying descriptions in a situation where explicit labeling is inappropriate. Results showed that there were group differences in all three cases, with the HFA group giving less efficient descriptions with respect to the relevant context than the comparison group. More revealing was the identification of distinct adaptation profiles among the HFA participants: those who had difficulty with all three levels, those who displayed Level 1 audience design but poor Level 2 and Level 3 design, and those demonstrated all three levels of audience design, like the majority of the comparison group. Higher structural language ability, rather than symptom severity or social skills, differentiated those HFA participants with typical adaptation profiles from those who displayed deficient audience design, consistent with previous reports of language use in autism.

  19. Applying an Integrative Framework of Executive Function to Preschoolers With Specific Language Impairment

    PubMed Central

    Plante, Elena; Doubleday, Kevin

    2017-01-01

    Purpose The first goal of this research was to compare verbal and nonverbal executive function abilities between preschoolers with and without specific language impairment (SLI). The second goal was to assess the group differences on 4 executive function components in order to determine if the components may be hierarchically related as suggested within a developmental integrative framework of executive function. Method This study included 26 4- and 5-year-olds diagnosed with SLI and 26 typically developing age- and sex-matched peers. Participants were tested on verbal and nonverbal measures of sustained selective attention, working memory, inhibition, and shifting. Results The SLI group performed worse compared with typically developing children on both verbal and nonverbal measures of sustained selective attention and working memory, the verbal inhibition task, and the nonverbal shifting task. Comparisons of standardized group differences between executive function measures revealed a linear increase with the following order: working memory, inhibition, shifting, and sustained selective attention. Conclusion The pattern of results suggests that preschoolers with SLI have deficits in executive functioning compared with typical peers, and deficits are not limited to verbal tasks. A significant linear relationship between group differences across executive function components supports the possibility of a hierarchical relationship between executive function skills. PMID:28724132

  20. Development of Grammatical Accuracy in English-Speaking Children With Cochlear Implants: A Longitudinal Study

    PubMed Central

    Spencer, Linda J.

    2017-01-01

    Purpose We sought to evaluate the development of grammatical accuracy in English-speaking children with cochlear implants (CIs) over a 3-year span. Method Ten children who received CIs before age 30 months participated in this study at 3, 4, and 5 years postimplantation. For the purpose of comparison, 10 children each at ages 3, 4, and 5 years with typical hearing were included as well. All children participated in a story-retell task. We computed percent grammatical communication units (PGCU) in the task. Results Children with CIs showed significant improvement in PGCU over the 3-year span. However, they produced lower PGCU than children with typical hearing who had matched hearing age at 4 and 5 years postimplantation. At the individual level, some children with CIs were able to produce PGCU comparable to children with typical hearing as early as 3 years after implantation. Better speech-perception skills at earlier time points were associated with higher PGCU at later time points. Moreover, children with and without CIs showed similar rankings in the types of grammatical errors. Conclusion Despite having auditory-perceptual and information-processing constraints, children who received CIs before age 30 months were able to produce grammatical sentences, albeit with a delayed pattern. PMID:28384729

  1. The Value of Non-Work Time in Cross-National Quality of Life Comparisons: The Case of the United States vs. the Netherlands

    ERIC Educational Resources Information Center

    Verbakel, Ellen; DiPrete, Thomas A.

    2008-01-01

    Comparisons of wellbeing between the United States and Western Europe generally show that most Americans have higher standards of living than do Western Europeans at comparable locations in their national income distributions. These comparisons of wellbeing typically privilege disposable income and cash transfers while ignoring other aspects of…

  2. Low-order modeling of internal heat transfer in biomass particle pyrolysis

    DOE PAGES

    Wiggins, Gavin M.; Daw, C. Stuart; Ciesielski, Peter N.

    2016-05-11

    We present a computationally efficient, one-dimensional simulation methodology for biomass particle heating under conditions typical of fast pyrolysis. Our methodology is based on identifying the rate limiting geometric and structural factors for conductive heat transport in biomass particle models with realistic morphology to develop low-order approximations that behave appropriately. Comparisons of transient temperature trends predicted by our one-dimensional method with three-dimensional simulations of woody biomass particles reveal good agreement, if the appropriate equivalent spherical diameter and bulk thermal properties are used. Here, we conclude that, for particle sizes and heating regimes typical of fast pyrolysis, it is possible to simulatemore » biomass particle heating with reasonable accuracy and minimal computational overhead, even when variable size, aspherical shape, anisotropic conductivity, and complex, species-specific internal pore geometry are incorporated.« less

  3. Low-Order Modeling of Internal Heat Transfer in Biomass Particle Pyrolysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wiggins, Gavin M.; Ciesielski, Peter N.; Daw, C. Stuart

    2016-06-16

    We present a computationally efficient, one-dimensional simulation methodology for biomass particle heating under conditions typical of fast pyrolysis. Our methodology is based on identifying the rate limiting geometric and structural factors for conductive heat transport in biomass particle models with realistic morphology to develop low-order approximations that behave appropriately. Comparisons of transient temperature trends predicted by our one-dimensional method with three-dimensional simulations of woody biomass particles reveal good agreement, if the appropriate equivalent spherical diameter and bulk thermal properties are used. We conclude that, for particle sizes and heating regimes typical of fast pyrolysis, it is possible to simulate biomassmore » particle heating with reasonable accuracy and minimal computational overhead, even when variable size, aspherical shape, anisotropic conductivity, and complex, species-specific internal pore geometry are incorporated.« less

  4. The Effectiveness of Self-regulatory Speech Training for Planning and Problem Solving in Children with Specific Language Impairment.

    PubMed

    Abdul Aziz, Safiyyah; Fletcher, Janet; Bayliss, Donna M

    2016-08-01

    Self-regulatory speech has been shown to be important for the planning and problem solving of children. Our intervention study, including comparisons to both wait-list and typically developing controls, examined the effectiveness of a training programme designed to improve self-regulatory speech, and consequently, the planning and problem solving performance of 87 (60 males, 27 females) children aged 4-7 years with Specific Language Impairment (SLI) who were delayed in their self-regulatory speech development. The self-regulatory speech and Tower of London (TOL) performance of children with SLI who received the intervention initially or after a waiting period was compared with that of 80 (48 male, 32 female) typically developing children who did not receive any intervention. Children were tested at three time points: Time 1- prior to intervention; Time 2 - after the first SLI group had received training and the second SLI group provided a wait-list control; and Time 3 - when the second SLI group had received training. At Time 1 children with SLI produced less self-regulatory speech and were impaired on the TOL relative to the typically developing children. At Time 2, the TOL performance of children with SLI in the first training group improved significantly, whereas there was no improvement for the second training group (the wait-list group). At Time 3, the second training group improved their TOL performance and the first group maintained their performance. No significant differences in TOL performance were evident between typically developing children and those with SLI at Time 3. Moreover, decreases in social speech and increases in inaudible muttering following self-regulatory speech training were associated with improvements in TOL performance. Together, the results show that self-regulatory speech training was effective in increasing self-regulatory speech and in improving planning and problem solving performance in children with SLI.

  5. Spatial coding of object typical size: evidence for a SNARC-like effect.

    PubMed

    Sellaro, Roberta; Treccani, Barbara; Job, Remo; Cubelli, Roberto

    2015-11-01

    The present study aimed to assess whether the representation of the typical size of objects can interact with response position codes in two-choice bimanual tasks, and give rise to a SNARC-like effect (faster responses when the representation of the typical size of the object to which the target stimulus refers corresponds to response side). Participants performed either a magnitude comparison task (in which they were required to judge whether the target was smaller or larger than a reference stimulus; Experiment 1) or a semantic decision task (in which they had to classify the target as belonging to either the category of living or non-living entities; Experiment 2). Target stimuli were pictures or written words referring to either typically large and small animals or inanimate objects. In both tasks, participants responded by pressing a left- or right-side button. Results showed that, regardless of the to-be-performed task (magnitude comparison or semantic decision) and stimulus format (picture or word), left responses were faster when the target represented typically small-sized entities, whereas right responses were faster for typically large-sized entities. These results provide evidence that the information about the typical size of objects is activated even if it is not requested by the task, and are consistent with the idea that objects' typical size is automatically spatially coded, as has been proposed to occur for number magnitudes. In this representation, small objects would be on the left and large objects would be on the right. Alternative interpretations of these results are also discussed.

  6. Can a clinical placement influence stigma? An analysis of measures of social distance.

    PubMed

    Moxham, Lorna; Taylor, Ellie; Patterson, Christopher; Perlman, Dana; Brighton, Renee; Sumskis, Susan; Keough, Emily; Heffernan, Tim

    2016-09-01

    The way people who experience mental illness are perceived by health care professionals, which often includes stigmatising attitudes, can have a significant impact on treatment outcomes and on their quality of life. To determine whether stigma towards people with mental illness varied for undergraduate nursing students who attended a non-traditional clinical placement called Recovery Camp compared to students who attended a 'typical' mental health clinical placement. Quasi-experimental. Seventy-nine third-year nursing students were surveyed; n=40 attended Recovery Camp (intervention), n=39 (comparison group) attended a 'typical' mental health clinical placement. All students completed the Social Distance Scale (SDS) pre- and post-placement and at three-month follow-up. Data analysis consisted of a one-way repeated measures analysis of variance (ANOVA) exploring parameter estimates between group scores across three time points. Two secondary repeated measures ANOVAs were performed to demonstrate the differences in SDS scores for each group across time. Pairwise comparisons demonstrated the differences between time intervals. A statistically significant difference in ratings of stigma between the intervention group and the comparison group existed. Parameter estimates revealed that stigma ratings for the intervention group were significantly reduced post-placement and remained consistently low at three-month follow-up. There was no significant difference in ratings of stigma for the comparison group over time. Students who attended Recovery Camp reported significant decreases in stigma towards people with a mental illness over time, compared to the typical placement group. Findings suggest that a therapeutic recreation based clinical placement was more successful in reducing stigma regarding mental illness in undergraduate nursing students compared to those who attended typical mental health clinical placements. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. Research study for effects of case flexibility on bearing loads and rotor stability

    NASA Technical Reports Server (NTRS)

    Fenwick, J. R.; Tarn, R. B.

    1984-01-01

    Methods to evaluate the effect of casing flexibility on rotor stability and component loads were developed. Recent Rocketdyne turbomachinery was surveyed to determine typical properties and frequencies versus running speed. A small generic rotor was run with a flexible case with parametric variations in casing properties for comparison with a rotor attached to rigid supports. A program for the IBM personal computer for interactive evaluation of rotors and casings is developed. The Root locus method is extended for use in rotor dynamics for symmetrical systems by transforming all motion and coupling into a single plane and using a 90 degree criterion when plotting loci.

  8. Development of Flow over Blunt-Nosed Slender Bodies at Transonic Mach Numbers

    NASA Astrophysics Data System (ADS)

    Yanamashetti, Gireesh; Suryanarayana, G. K.; Mukherjee, Rinku

    2017-04-01

    Comparisons of the development of flow over a cylinder with a 20° cone nose and a cylinder with an ogive nose, which represent typical heat-shield configurations are studied using CFD and experiments at transonic Mach numbers. The Cp plots are studied to locate expansion or separation. Experiments are carried out at M = 0.8, 0.9, 0.95 and 1.1 and Re ≈ 2.45 × 106. Computations are carried out using the commercial package, FLUENT 6.3. Inadequate spatial resolution of pressure ports in experiments as well as limitations of the CFD tool result in some differences in experimental and CFD results.

  9. Tracer water transport and subgrid precipitation variation within atmospheric general circulation models

    NASA Astrophysics Data System (ADS)

    Koster, Randal D.; Eagleson, Peter S.; Broecker, Wallace S.

    1988-03-01

    A capability is developed for monitoring tracer water movement in the three-dimensional Goddard Institute for Space Science Atmospheric General Circulation Model (GCM). A typical experiment with the tracer water model follows water evaporating from selected grid squares and determines where this water first returns to the Earth's surface as precipitation or condensate, thereby providing information on the lateral scales of hydrological transport in the GCM. Through a comparison of model results with observations in nature, inferences can be drawn concerning real world water transport. Tests of the tracer water model include a comparison of simulated and observed vertically-integrated vapor flux fields and simulations of atomic tritium transport from the stratosphere to the oceans. The inter-annual variability of the tracer water model results is also examined.

  10. Tracer water transport and subgrid precipitation variation within atmospheric general circulation models

    NASA Technical Reports Server (NTRS)

    Koster, Randal D.; Eagleson, Peter S.; Broecker, Wallace S.

    1988-01-01

    A capability is developed for monitoring tracer water movement in the three-dimensional Goddard Institute for Space Science Atmospheric General Circulation Model (GCM). A typical experiment with the tracer water model follows water evaporating from selected grid squares and determines where this water first returns to the Earth's surface as precipitation or condensate, thereby providing information on the lateral scales of hydrological transport in the GCM. Through a comparison of model results with observations in nature, inferences can be drawn concerning real world water transport. Tests of the tracer water model include a comparison of simulated and observed vertically-integrated vapor flux fields and simulations of atomic tritium transport from the stratosphere to the oceans. The inter-annual variability of the tracer water model results is also examined.

  11. Parent perceptions of the quality of life of pet dogs living with neuro-typically developing and neuro-atypically developing children: An exploratory study

    PubMed Central

    Wright, Hannah F.; Mills, Daniel S.

    2017-01-01

    There is growing scientific and societal recognition of the role that pet dogs can play in healthy development of children; both those who are neuro-typically developing and those who live with a neuro-developmental disorder, such as autism or attention deficit hyperactivity disorder. However, little attention has been paid to how living with children positively and negatively affects quality of life of a pet dog. In this exploratory study we conducted semi-structured interviews with parents of neuro-typically developing children (n = 18) and those with a neuro-developmental disorder (n = 18) who owned a pet dog, until no new factors were identified. Living with children brought potentially positive benefits to the dog’s life including: imposition of a routine, participation in recreational activities and the development of a strong bond between the child and the dog. The importance of maintaining a routine was particularly prevalent in families with children with neuro-developmental disorders. Potential negative factors included having to cope with child meltdowns and tantrums, over stimulation from child visitors, harsh contact and rough and tumble play with the child. The regularity and intensity of meltdowns and tantrums was particularly evident in responses from parents with children with a neuro-developmental disorder. However, child visitors and rough play and contact were mentioned similarly across the groups. Protective factors included having a safe haven for the dog to escape to, parent’s awareness of stress signs and child education in dog-interaction. Parents were also asked to complete a stress response scale to provide an initial quantitative comparison of stress responses between dogs living with the two family-types. Parents with neuro-typically developing children more frequently observed their dog rapidly running away from a situation and less frequently observed their dog widening their eyes, than parents with children with a neuro-developmental disorder. We propose the development of a stress audit based on the findings reported here, to prevent potential dangerous situations, which may lead to dog bites and dog relinquishment and allow owners to maximise the benefits of dog ownership. PMID:28953961

  12. Parent perceptions of the quality of life of pet dogs living with neuro-typically developing and neuro-atypically developing children: An exploratory study.

    PubMed

    Hall, Sophie S; Wright, Hannah F; Mills, Daniel S

    2017-01-01

    There is growing scientific and societal recognition of the role that pet dogs can play in healthy development of children; both those who are neuro-typically developing and those who live with a neuro-developmental disorder, such as autism or attention deficit hyperactivity disorder. However, little attention has been paid to how living with children positively and negatively affects quality of life of a pet dog. In this exploratory study we conducted semi-structured interviews with parents of neuro-typically developing children (n = 18) and those with a neuro-developmental disorder (n = 18) who owned a pet dog, until no new factors were identified. Living with children brought potentially positive benefits to the dog's life including: imposition of a routine, participation in recreational activities and the development of a strong bond between the child and the dog. The importance of maintaining a routine was particularly prevalent in families with children with neuro-developmental disorders. Potential negative factors included having to cope with child meltdowns and tantrums, over stimulation from child visitors, harsh contact and rough and tumble play with the child. The regularity and intensity of meltdowns and tantrums was particularly evident in responses from parents with children with a neuro-developmental disorder. However, child visitors and rough play and contact were mentioned similarly across the groups. Protective factors included having a safe haven for the dog to escape to, parent's awareness of stress signs and child education in dog-interaction. Parents were also asked to complete a stress response scale to provide an initial quantitative comparison of stress responses between dogs living with the two family-types. Parents with neuro-typically developing children more frequently observed their dog rapidly running away from a situation and less frequently observed their dog widening their eyes, than parents with children with a neuro-developmental disorder. We propose the development of a stress audit based on the findings reported here, to prevent potential dangerous situations, which may lead to dog bites and dog relinquishment and allow owners to maximise the benefits of dog ownership.

  13. Neuropsychological Comparison of Children with Heavy Prenatal Alcohol Exposure and an IQ-Matched Comparison Group

    PubMed Central

    Vaurio, Linnea; Riley, Edward P.; Mattson, Sarah N.

    2012-01-01

    An objective in current research on children with fetal alcohol spectrum disorders (FASD) is to determine neurobehavioral profiles to identify affected individuals. Deficits observed when children with FASD are compared to typically developing controls may be confounded by lower IQ scores in the subjects with FASD. To determine if prenatal alcohol exposure is associated with neurobehavioral deficits after controlling for IQ differences, multivariate analyses were conducted to compare alcohol-exposed (ALC) subjects to a comparison group closely matched on IQ (IQC). The initial analysis included a broad neuropsychological battery with measures of language, executive function, visual–motor integration, motor ability, and academic achievement. Additional, in depth comparisons focused on visual sustained attention, verbal learning and memory and parent/guardian-reported behavior problems. Group differences (ALC < IQC) were found on verbal learning and parent-rated behavior problems. Group differences were marginally significant (measures within the broad neuropsychological comparison) or not significant (visual attention, retention of verbal material) on the remaining comparisons. Therefore, some deficits (e.g., verbal learning and behavior problems) in children with heavy prenatal alcohol exposure cannot be explained by the lower FSIQ observed in the population. These areas of relative weakness could be useful in distinguishing children with FASD from other children with lowered IQ. PMID:21349236

  14. The Formalization of Fairness: Issues in Testing for Measurement Invariance Using Subtest Scores

    ERIC Educational Resources Information Center

    Molenaar, Dylan; Borsboom, Denny

    2013-01-01

    Measurement invariance is an important prerequisite for the adequate comparison of group differences in test scores. In psychology, measurement invariance is typically investigated by means of linear factor analyses of subtest scores. These subtest scores typically result from summing the item scores. In this paper, we discuss 4 possible problems…

  15. The DalHouses: 100 new photographs of houses with ratings of typicality, familiarity, and degree of similarity to faces.

    PubMed

    Filliter, Jillian H; Glover, Jacqueline M; McMullen, Patricia A; Salmon, Joshua P; Johnson, Shannon A

    2016-03-01

    Houses have often been used as comparison stimuli in face-processing studies because of the many attributes they share with faces (e.g., distinct members of a basic category, consistent internal features, mono-orientation, and relative familiarity). Despite this, no large, well-controlled databases of photographs of houses that have been developed for research use currently exist. To address this gap, we photographed 100 houses and carefully edited these images. We then asked 41 undergraduate students (18 to 31 years of age) to rate each house on three dimensions: typicality, likeability, and face-likeness. The ratings had a high degree of face validity, and analyses revealed a significant positive correlation between typicality and likeability. We anticipate that this stimulus set (i.e., the DalHouses) and the associated ratings will prove useful to face-processing researchers by minimizing the effort required to acquire stimuli and allowing for easier replication and extension of studies. The photographs of all 100 houses and their ratings data can be obtained at http://dx.doi.org/10.6084/m9.figshare.1279430.

  16. Comparison of public peak detection algorithms for MALDI mass spectrometry data analysis.

    PubMed

    Yang, Chao; He, Zengyou; Yu, Weichuan

    2009-01-06

    In mass spectrometry (MS) based proteomic data analysis, peak detection is an essential step for subsequent analysis. Recently, there has been significant progress in the development of various peak detection algorithms. However, neither a comprehensive survey nor an experimental comparison of these algorithms is yet available. The main objective of this paper is to provide such a survey and to compare the performance of single spectrum based peak detection methods. In general, we can decompose a peak detection procedure into three consequent parts: smoothing, baseline correction and peak finding. We first categorize existing peak detection algorithms according to the techniques used in different phases. Such a categorization reveals the differences and similarities among existing peak detection algorithms. Then, we choose five typical peak detection algorithms to conduct a comprehensive experimental study using both simulation data and real MALDI MS data. The results of comparison show that the continuous wavelet-based algorithm provides the best average performance.

  17. Data for Room Fire Model Comparisons

    PubMed Central

    Peacock, Richard D.; Davis, Sanford; Babrauskas, Vytenis

    1991-01-01

    With the development of models to predict fire growth and spread in buildings, there has been a concomitant evolution in the measurement and analysis of experimental data in real-scale fires. This report presents the types of analyses that can be used to examine large-scale room fire test data to prepare the data for comparison with zone-based fire models. Five sets of experimental data which can be used to test the limits of a typical two-zone fire model are detailed. A standard set of nomenclature describing the geometry of the building and the quantities measured in each experiment is presented. Availability of ancillary data (such as smaller-scale test results) is included. These descriptions, along with the data (available in computer-readable form) should allow comparisons between the experiment and model predictions. The base of experimental data ranges in complexity from one room tests with individual furniture items to a series of tests conducted in a multiple story hotel equipped with a zoned smoke control system. PMID:28184121

  18. Data for Room Fire Model Comparisons.

    PubMed

    Peacock, Richard D; Davis, Sanford; Babrauskas, Vytenis

    1991-01-01

    With the development of models to predict fire growth and spread in buildings, there has been a concomitant evolution in the measurement and analysis of experimental data in real-scale fires. This report presents the types of analyses that can be used to examine large-scale room fire test data to prepare the data for comparison with zone-based fire models. Five sets of experimental data which can be used to test the limits of a typical two-zone fire model are detailed. A standard set of nomenclature describing the geometry of the building and the quantities measured in each experiment is presented. Availability of ancillary data (such as smaller-scale test results) is included. These descriptions, along with the data (available in computer-readable form) should allow comparisons between the experiment and model predictions. The base of experimental data ranges in complexity from one room tests with individual furniture items to a series of tests conducted in a multiple story hotel equipped with a zoned smoke control system.

  19. International perspectives on education, training, and practice in clinical neuropsychology: comparison across 14 countries around the world.

    PubMed

    Grote, Christopher L; Novitski, Julia I

    2016-11-01

    To review and summarize data provided by special issue authors regarding the education, training, and practice of neuropsychologists from 14 surveyed countries. A table was constructed to present an overview of variables of interest. There is considerable diversity among surveyed countries regarding the education and training required to enter practice as a clinical neuropsychologist. Clinical neuropsychologists are typically well compensated, at least in comparison to what constitutes an average salary in each country. Despite substantial variations in education and training pathways, and availability of neuropsychologists from country to country, two common areas for future development are suggested. First, identification, development, and measurement of core competencies for neuropsychological education and practice are needed that can serve as a unifying element for the world's clinical neuropsychologists. Second, greater emphasis on recognizing and addressing the need for assessment and treatment of diverse populations is needed if the world's citizens can hope to benefit from the expertise of practitioners in our field.

  20. A comparison of methods of fitting several models to nutritional response data.

    PubMed

    Vedenov, D; Pesti, G M

    2008-02-01

    A variety of models have been proposed to fit nutritional input-output response data. The models are typically nonlinear; therefore, fitting the models usually requires sophisticated statistical software and training to use it. An alternative tool for fitting nutritional response models was developed by using widely available and easier-to-use Microsoft Excel software. The tool, implemented as an Excel workbook (NRM.xls), allows simultaneous fitting and side-by-side comparisons of several popular models. This study compared the results produced by the tool we developed and PROC NLIN of SAS. The models compared were the broken line (ascending linear and quadratic segments), saturation kinetics, 4-parameter logistics, sigmoidal, and exponential models. The NRM.xls workbook provided results nearly identical to those of PROC NLIN. Furthermore, the workbook successfully fit several models that failed to converge in PROC NLIN. Two data sets were used as examples to compare fits by the different models. The results suggest that no particular nonlinear model is necessarily best for all nutritional response data.

  1. Parametric Study of Fire Performance of Concrete Filled Hollow Steel Section Columns with Circular and Square Cross-Section

    NASA Astrophysics Data System (ADS)

    Nurfaidhi Rizalman, Ahmad; Tahir, Ng Seong Yap Mahmood Md; Mohammad, Shahrin

    2018-03-01

    Concrete filled hollow steel section column have been widely accepted by structural engineers and designers for high rise construction due to the benefits of combining steel and concrete. The advantages of concrete filled hollow steel section column include higher strength, ductility, energy absorption capacity, and good structural fire resistance. In this paper, comparison on the fire performance between circular and square concrete filled hollow steel section column is established. A three-dimensional finite element package, ABAQUS, was used to develop the numerical model to study the temperature development, critical temperature, and fire resistance time of the selected composite columns. Based on the analysis and comparison of typical parameters, the effect of equal cross-sectional size for both steel and concrete, concrete types, and thickness of external protection on temperature distribution and structural fire behaviour of the columns are discussed. The result showed that concrete filled hollow steel section column with circular cross-section generally has higher fire resistance than the square section.

  2. The effect of gender on the neuroanatomy of children with autism spectrum disorders: a support vector machine case-control study.

    PubMed

    Retico, Alessandra; Giuliano, Alessia; Tancredi, Raffaella; Cosenza, Angela; Apicella, Fabio; Narzisi, Antonio; Biagi, Laura; Tosetti, Michela; Muratori, Filippo; Calderoni, Sara

    2016-01-01

    Genetic, hormonal, and environmental factors contribute since infancy to sexual dimorphism in regional brain structures of subjects with typical development. However, the neuroanatomical differences between male and female children with autism spectrum disorders (ASD) are an intriguing and still poorly investigated issue. This study aims to evaluate whether the brain of young children with ASD exhibits sex-related structural differences and if a correlation exists between clinical ASD features and neuroanatomical underpinnings. A total of 152 structural MRI scans were analysed. Specifically, 76 young children with ASD (38 males and 38 females; 2-7 years of age; mean = 53 months, standard deviation = 17 months) were evaluated employing a support vector machine (SVM)-based analysis of the grey matter (GM). Group comparisons consisted of 76 age-, gender- and non-verbal-intelligence quotient-matched children with typical development or idiopathic developmental delay without autism. For both genders combined, SVM showed a significantly increased GM volume in young children with ASD with respect to control subjects, predominantly in the bilateral superior frontal gyrus (Brodmann area -BA- 10), bilateral precuneus (BA 31), bilateral superior temporal gyrus (BA 20/22), whereas less GM in patients with ASD was found in right inferior temporal gyrus (BA 37). For the within gender comparisons (i.e., females with ASD vs. controls and males with ASD vs. controls), two overlapping regions in bilateral precuneus (BA 31) and left superior frontal gyrus (BA 9/10) were detected. Sex-by-group analyses revealed in males with ASD compared to matched controls two male-specific regions of increased GM volume (left middle occipital gyrus-BA 19-and right superior temporal gyrus-BA 22). Comparisons in females with and without ASD demonstrated increased GM volumes predominantly in the bilateral frontal regions. Additional regions of significantly increased GM volume in the right anterior cingulate cortex (BA 32) and right cerebellum were typical only of females with ASD. Despite the specific behavioural correlates of sex-dimorphism in ASD, brain morphology as yet remains unclear and requires future dedicated investigations. This study provides evidence of structural brain gender differences in young children with ASD that possibly contribute to the different phenotypic disease manifestations in males and females.

  3. Adolescents with Developmental Dyscalculia Do Not Have a Generalized Magnitude Deficit - Processing of Discrete and Continuous Magnitudes.

    PubMed

    McCaskey, Ursina; von Aster, Michael; O'Gorman Tuura, Ruth; Kucian, Karin

    2017-01-01

    The link between number and space has been discussed in the literature for some time, resulting in the theory that number, space and time might be part of a generalized magnitude system. To date, several behavioral and neuroimaging findings support the notion of a generalized magnitude system, although contradictory results showing a partial overlap or separate magnitude systems are also found. The possible existence of a generalized magnitude processing area leads to the question how individuals with developmental dyscalculia (DD), known for deficits in numerical-arithmetical abilities, process magnitudes. By means of neuropsychological tests and functional magnetic resonance imaging (fMRI) we aimed to examine the relationship between number and space in typical and atypical development. Participants were 16 adolescents with DD (14.1 years) and 14 typically developing (TD) peers (13.8 years). In the fMRI paradigm participants had to perform discrete (arrays of dots) and continuous magnitude (angles) comparisons as well as a mental rotation task. In the neuropsychological tests, adolescents with dyscalculia performed significantly worse in numerical and complex visuo-spatial tasks. However, they showed similar results to TD peers when making discrete and continuous magnitude decisions during the neuropsychological tests and the fMRI paradigm. A conjunction analysis of the fMRI data revealed commonly activated higher order visual (inferior and middle occipital gyrus) and parietal (inferior and superior parietal lobe) magnitude areas for the discrete and continuous magnitude tasks. Moreover, no differences were found when contrasting both magnitude processing conditions, favoring the possibility of a generalized magnitude system. Group comparisons further revealed that dyscalculic subjects showed increased activation in domain general regions, whilst TD peers activate domain specific areas to a greater extent. In conclusion, our results point to the existence of a generalized magnitude system in the occipito-parietal stream in typical development. The detailed investigation of spatial and numerical magnitude abilities in DD reveals that the deficits in number processing and arithmetic cannot be explained with a general magnitude deficiency. Our results further indicate that multiple neuro-cognitive components might contribute to the explanation of DD.

  4. Adolescents with Developmental Dyscalculia Do Not Have a Generalized Magnitude Deficit – Processing of Discrete and Continuous Magnitudes

    PubMed Central

    McCaskey, Ursina; von Aster, Michael; O’Gorman Tuura, Ruth; Kucian, Karin

    2017-01-01

    The link between number and space has been discussed in the literature for some time, resulting in the theory that number, space and time might be part of a generalized magnitude system. To date, several behavioral and neuroimaging findings support the notion of a generalized magnitude system, although contradictory results showing a partial overlap or separate magnitude systems are also found. The possible existence of a generalized magnitude processing area leads to the question how individuals with developmental dyscalculia (DD), known for deficits in numerical-arithmetical abilities, process magnitudes. By means of neuropsychological tests and functional magnetic resonance imaging (fMRI) we aimed to examine the relationship between number and space in typical and atypical development. Participants were 16 adolescents with DD (14.1 years) and 14 typically developing (TD) peers (13.8 years). In the fMRI paradigm participants had to perform discrete (arrays of dots) and continuous magnitude (angles) comparisons as well as a mental rotation task. In the neuropsychological tests, adolescents with dyscalculia performed significantly worse in numerical and complex visuo-spatial tasks. However, they showed similar results to TD peers when making discrete and continuous magnitude decisions during the neuropsychological tests and the fMRI paradigm. A conjunction analysis of the fMRI data revealed commonly activated higher order visual (inferior and middle occipital gyrus) and parietal (inferior and superior parietal lobe) magnitude areas for the discrete and continuous magnitude tasks. Moreover, no differences were found when contrasting both magnitude processing conditions, favoring the possibility of a generalized magnitude system. Group comparisons further revealed that dyscalculic subjects showed increased activation in domain general regions, whilst TD peers activate domain specific areas to a greater extent. In conclusion, our results point to the existence of a generalized magnitude system in the occipito-parietal stream in typical development. The detailed investigation of spatial and numerical magnitude abilities in DD reveals that the deficits in number processing and arithmetic cannot be explained with a general magnitude deficiency. Our results further indicate that multiple neuro-cognitive components might contribute to the explanation of DD. PMID:28373834

  5. Maternal regulation of child affect in externalizing and typically-developing children.

    PubMed

    Lougheed, Jessica P; Hollenstein, Tom; Lichtwarck-Aschoff, Anna; Granic, Isabela

    2015-02-01

    Temporal contingencies between children's affect and maternal behavior play a role in the development of children's externalizing problems. The goal of the current study was to use a microsocial approach to compare dyads with externalizing dysregulation (N =191) to healthy controls (N = 54) on maternal supportive regulation of children's negative and positive affect. Children were between the ages of 8 and 12 years. Mother-child dyads participated in conflict and positive discussions, and child affect and maternal supportive affect regulation were coded in real time. First, no group differences on overall levels of mother supportive regulation or child affect were found. Second, three event history analyses in a 2-level Cox hazard regression framework were used to predict the hazard rate of (a) maternal supportiveness, and of children's transitions (b) out of negative affect and (c) into positive affect. The hazard rate of maternal supportiveness, regardless of child affect, was not different between groups. However, as expected, the likelihood of mothers' supportive responses to children's negative affect was lower in externalizing than comparison dyads. In addition, children with externalizing problems were significantly less likely than typically developing children to transition out of negative affect in response to maternal supportiveness. The likelihood of both typically developing children and children with externalizing problems transitioning into positive affect were not related to specific occurrences of maternal supportiveness. Results of the current study show the importance of temporal dynamics in mother-child interactions in the emergence of children's externalizing problems. PsycINFO Database Record (c) 2015 APA, all rights reserved.

  6. Social functioning and facial expression recognition in children with neurofibromatosis type 1.

    PubMed

    Allen, T; Willard, V W; Anderson, L M; Hardy, K K; Bonner, M J

    2016-03-01

    This study examined social functioning and facial expression recognition (FER) in children with neurofibromatosis type 1 (NF1) compared to typically developing peers. Specifically, the current research aimed to identify hypothesised relationships between neurocognitive ability, FER and social functioning. Children, ages 8 to 16, with NF1 (n = 23) and typically developing peers (n = 23) were recruited during regularly scheduled clinic visits and through advertisements on an institutional clinical trials website, respectively. Participants completed a measure of FER, an abbreviated intelligence test and questionnaires regarding their quality of life and behavioural functioning. Parents were also asked to complete questionnaires regarding the social-emotional and cognitive functioning of their child. As expected, there were significant differences between children with NF1 and typically developing peers across domains of social functioning and FER. Within the sample of children with NF1, there were no significant associations observed between cognitive measures, social functioning and facial recognition skills. Children with NF1 exhibited high rates of social impairment and weak FER skills compared to controls. The absence of associations between FER with cognitive and social variables, however, suggests something unique about this skill in children with NF1. Theoretical comparisons are made to children with autism spectrum disorders, as this condition may serve as a potentially useful model in better understanding FER in children with NF1. © 2016 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

  7. Early Language Development in Infants and Toddlers with Fragile X Syndrome: Change over Time and the Role of Attention

    PubMed Central

    Kover, Sara T.; McCary, Lindsay M.; Ingram, Alexandra M.; Hatton, Deborah D.; Roberts, Jane E.

    2017-01-01

    Fragile X syndrome (FXS) is associated with significant language and communication delays, as well as problems with attention. This study investigated early language abilities in infants and toddlers with FXS (n = 13) and considered visual attention as a predictor of those skills. We found that language abilities increased over the study period of 9 to 24 months with moderate correlations among language assessments. In comparison to typically developing infants (n = 11), language skills were delayed beyond chronological age- and developmental level-expectations. Aspects of early visual attention predicted later language ability. Atypical visual attention is an important aspect of the FXS phenotype with implications for early language development, particularly in the domain of vocabulary. PMID:25715182

  8. A Bayesian Missing Data Framework for Generalized Multiple Outcome Mixed Treatment Comparisons

    ERIC Educational Resources Information Center

    Hong, Hwanhee; Chu, Haitao; Zhang, Jing; Carlin, Bradley P.

    2016-01-01

    Bayesian statistical approaches to mixed treatment comparisons (MTCs) are becoming more popular because of their flexibility and interpretability. Many randomized clinical trials report multiple outcomes with possible inherent correlations. Moreover, MTC data are typically sparse (although richer than standard meta-analysis, comparing only two…

  9. The motion of bubbles inside drops in containerless processing

    NASA Technical Reports Server (NTRS)

    Shankar, N.; Annamalai, P.; Cole, R.; Subramanian, R. S.

    1982-01-01

    A theoretical model of thermocapillary bubble motion inside a drop, located in a space laboratory, due to an arbitrary axisymmetric temperature distribution on the drop surface was constructed. Typical results for the stream function and temperature fields as well as the migration velocity of the bubble were obtained in the quasistatic limit. The motion of bubbles in a rotating body of liquid was studied experimentally, and an approximate theoretical model was developed. Comparison of the experimental observations of the bubble trajectories and centering times with theoretical predictions lends qualified support to the theory.

  10. An improved computational approach for multilevel optimum design

    NASA Technical Reports Server (NTRS)

    Haftka, R. T.

    1984-01-01

    A penalty-function algorithm employing Newton's method with approximate second derivatives (Haftka and Starnes, 1980) is developed for two-level hierarchical design optimization problems. The difficulties posed by discontinuous behavior in typical multilevel problems are explained and illustrated for the case of a three-bar truss; the algorithm is formulated; and its advantages are demonstrated in the problem of a portal framework having three beams (described by six cross-section parameters), subjected to two loading conditions, and to be constructed in six different materials for comparison. The final design parameters are listed in a table.

  11. The use of conjunctions by children with typical language development.

    PubMed

    Glória, Yasmin Alves Leão; Hanauer, Letícia Pessota; Wiethan, Fernanda Marafiga; Nóro, Letícia Arruda; Mota, Helena Bolli

    2016-07-04

    To investigate the use of conjunctions in the spontaneous speech of three years old children with typical language development, who live in Santa Maria - RS. 45 children, aged 3:0;0 - 3:11;29 (years:months;days) from the database of the Center for the Study of Language and Speech (CELF) participated of this study. The spontaneous speech of each child was transcribed and followed by analysis of the samples to identify the types of conjunctions for each age group. The samples were statistically analyzed using the R software that allowed the evaluation of the number and type of conjunctions used in each age group by comparing them with each other. The data indicated that the higher the age of the child, the greater the number of types of conjunctions used by them. The comparison between age groups showed significant differences when comparing the average number of conjunctions per age group, as well as for additive conjunctions and subordinating conjunctions. At age of three the children begin to develop the grammatical use of conjunctions, early appearing additive, adversative and explanatory coordinating conjunctions, and at 3:6 they are able to use the most complex conjunctions, as subordinating conjunctions.

  12. Mother-Stranger Comparisons of Social Attention in Jealousy Context and Attachment in HFASD and Typical Preschoolers

    ERIC Educational Resources Information Center

    Bauminger-Zvieli, Nirit; Kugelmass, Dana Shoham

    2013-01-01

    Affective bonding, social attention, and intersubjective capabilities are all conditions for jealousy, and are deficient in autism. Thus, examining jealousy and attachment may elucidate the socioemotional deficit in autism spectrum disorders (ASD). Jealousy was provoked in 30 high-functioning children with ASD (HFASD) and 30 typical children (ages…

  13. How Do Technology-Enhanced Inquiry Science Units Impact Classroom Learning?

    ERIC Educational Resources Information Center

    Lee, Hee-Sun; Linn, Marcia C.; Varma, Keisha; Liu, Ou Lydia

    2010-01-01

    We investigated how student understanding of complex science topics was impacted when 27 teachers switched from typical to inquiry instruction in a delayed cohort comparison design study. For the same set of science topics, the teachers used typical methods of instruction in the first year and online, visualization rich inquiry units in the second…

  14. A Comparison of Reading Growth and Outcomes of Kindergarten Students with Cognitive Impairments to Their Typical Peers: The Impact of Instruction

    ERIC Educational Resources Information Center

    Folsom, Jessica Sidler

    2012-01-01

    This research addressed the early reading instruction of students with cognitive impairments included in general education kindergarten classrooms. Research from 2002 to 2011 on early reading instruction for students with mental retardation were reviewed and current trends in measurement, typical instruction, intervention, and achievement were…

  15. A Comparison of Two Methods of Teaching an Elementary School Science Methods Course at Hunter College.

    ERIC Educational Resources Information Center

    Graeber, Mary

    The typical approach to the teaching of an elementary school science methods course for undergraduate students was compared with an experimental approach based upon activities appearing in the Conceptually Oriented Program in Elementary Science (COPES) teacher's guides. The typical approach was characterized by a coverage of many topics and a…

  16. A comparison of two approaches for representing AAC vocabulary for young children.

    PubMed

    Worah, Smita; McNaughton, David; Light, Janice; Benedek-Wood, Elizabeth

    2015-01-01

    Young children with complex communication needs often experience difficulty in using currently available graphic symbol systems as a method of augmentative and alternative communication (AAC). Information on young children's performance with graphic representations based on this population's conceptualizations of these vocabulary items may assist in the development of more effective AAC systems. This study developed Developmentally Appropriate Symbols (DAS) for 10 early emerging vocabulary concepts using procedures designed to address both conceptual and appeal issues for graphic representations for young children. Using a post-test only, between-subjects comparison group design, 40 typically-developing 2.5-3.5-year-old children were randomly assigned to receive a brief training in either of two different types of graphic symbol sets: (a) DAS or (b) Picture Communication Symbols (PCS), a, commercially available graphic symbol system. Results of a two sample independent t-test provide evidence that children in the DAS condition correctly identified more symbols than children trained with the PCS symbols. There was no evidence of a preference between the symbol sets. The results provide support for careful consideration of children's use and understanding of language in developing AAC systems for young children.

  17. Atypical Categorization in Children with High Functioning Autism Spectrum Disorder

    PubMed Central

    Church, Barbara A.; Krauss, Maria S.; Lopata, Christopher; Toomey, Jennifer A.; Thomeer, Marcus L.; Coutinho, Mariana V.; Volker, Martin A.; Mercado, Eduardo

    2010-01-01

    Children with autism spectrum disorder process many perceptual and social events differently from typically developing children, suggesting that they may also form and recognize categories differently. We used a dot pattern categorization task and prototype comparison modeling to compare categorical processing in children with high functioning autism spectrum disorder and matched typical controls. We were interested in whether there were differences in how children with autism use average similarity information about a category to make decisions. During testing, the group with autism spectrum disorder endorsed prototypes less and was seemingly less sensitive to differences between to-be-categorized items and the prototype. The findings suggest that individuals with high functioning autism spectrum disorder are less likely to use overall average similarity when forming categories or making categorical decisions. Such differences in category formation and use may negatively impact processing of socially relevant information, such as facial expressions. PMID:21169581

  18. A Comparison of Topography-based and Selection-based Verbal Behavior in Typically Developed Children and Developmentally Disabled Persons with Autism

    PubMed Central

    Vignes, Tore

    2007-01-01

    This study is a replication of Sundberg and Sundberg (1990) that compared topography-based verbal behavior with selection-based verbal behavior in terms of acquisition, accuracy, and testing for the emergence of a new verbal relation. Participants were three typical children and three developmentally disabled persons with autism. The study sought to determine which paradigm (topography-based or selection-based) resulted in more rapid acquisition of tacts and intraverbals, which was associated with the fewest errors, and which paradigm resulted in the emergence of the highest number of new verbal relations. The results of the study showed that the six participants performed quite differently from one another. Most importantly, the results from the person with autism contradicted previous findings favoring selection-based verbal behavior over topography-based approaches for teaching verbal behavior to low-functioning individuals. PMID:22477385

  19. Four-body trajectory optimization

    NASA Technical Reports Server (NTRS)

    Pu, C. L.; Edelbaum, T. N.

    1973-01-01

    A collection of typical three-body trajectories from the L1 libration point on the sun-earth line to the earth is presented. These trajectories in the sun-earth system are grouped into four distinct families which differ in transfer time and delta V requirements. Curves showing the variations of delta V with respect to transfer time, and typical two and three-impulse primer vector histories, are included. The development of a four-body trajectory optimization program to compute fuel optimal trajectories between the earth and a point in the sun-earth-moon system are also discussed. Methods for generating fuel optimal two-impulse trajectories which originate at the earth or a point in space, and fuel optimal three-impulse trajectories between two points in space, are presented. A brief qualitative comparison of these methods is given. An example of a four-body two-impulse transfer from the Li libration point to the earth is included.

  20. Artificial intelligence in peer review: How can evolutionary computation support journal editors?

    PubMed

    Mrowinski, Maciej J; Fronczak, Piotr; Fronczak, Agata; Ausloos, Marcel; Nedic, Olgica

    2017-01-01

    With the volume of manuscripts submitted for publication growing every year, the deficiencies of peer review (e.g. long review times) are becoming more apparent. Editorial strategies, sets of guidelines designed to speed up the process and reduce editors' workloads, are treated as trade secrets by publishing houses and are not shared publicly. To improve the effectiveness of their strategies, editors in small publishing groups are faced with undertaking an iterative trial-and-error approach. We show that Cartesian Genetic Programming, a nature-inspired evolutionary algorithm, can dramatically improve editorial strategies. The artificially evolved strategy reduced the duration of the peer review process by 30%, without increasing the pool of reviewers (in comparison to a typical human-developed strategy). Evolutionary computation has typically been used in technological processes or biological ecosystems. Our results demonstrate that genetic programs can improve real-world social systems that are usually much harder to understand and control than physical systems.

  1. Friction and wear behavior of aluminum and composite I-beam stiffened airplane skins

    NASA Technical Reports Server (NTRS)

    Jackson, K. E.

    1985-01-01

    Friction and wear behavior was determined for I-beam stiffened skins constructed of aluminum, graphite-epoxy composite, and glass hybrid composite under abrasive loading conditions typical of those occurring on the underside of a transport airplane during an emergency belly landing. A test apparatus was developed to abrade the test specimens on actual runway surface under a range of pressures (2-5 psi) and velocities (16-50 mph). These parameters were chosen to fall within the range of conditions typical of an airframe sliding on a runway surface. The effects of the test variables on the wear rate and the coefficient of friction are discussed and comparisons are made between the composite materials and aluminum. In addition, the test apparatus was equipped to monitor the temperature variations on the backside of the skins during abrasion and these results are presented.

  2. Integrated Data Analysis for Fusion: A Bayesian Tutorial for Fusion Diagnosticians

    NASA Astrophysics Data System (ADS)

    Dinklage, Andreas; Dreier, Heiko; Fischer, Rainer; Gori, Silvio; Preuss, Roland; Toussaint, Udo von

    2008-03-01

    Integrated Data Analysis (IDA) offers a unified way of combining information relevant to fusion experiments. Thereby, IDA meets with typical issues arising in fusion data analysis. In IDA, all information is consistently formulated as probability density functions quantifying uncertainties in the analysis within the Bayesian probability theory. For a single diagnostic, IDA allows the identification of faulty measurements and improvements in the setup. For a set of diagnostics, IDA gives joint error distributions allowing the comparison and integration of different diagnostics results. Validation of physics models can be performed by model comparison techniques. Typical data analysis applications benefit from IDA capabilities of nonlinear error propagation, the inclusion of systematic effects and the comparison of different physics models. Applications range from outlier detection, background discrimination, model assessment and design of diagnostics. In order to cope with next step fusion device requirements, appropriate techniques are explored for fast analysis applications.

  3. Daily Sleep Patterns, Sleep Quality, and Sleep Hygiene Among Parent–Child Dyads of Young Children Newly Diagnosed With Juvenile Idiopathic Arthritis and Typically Developing Children

    PubMed Central

    Chen, Maida Lynn; Cain, Kevin C.; Ringold, Sarah; Wallace, Carol A.; Ward, Teresa M.

    2016-01-01

    Objectives Describe daily sleep patterns, sleep quality, and sleep hygiene in 2–5-year-old children newly diagnosed with juvenile idiopathic arthritis (JIA) and their parents in comparison with typically developing (TD) children and parents. Methods Participants (13 JIA, 16 TD parent–child dyads) wore actigraphs for 10 days. Parents completed sleep diaries and sleep hygiene survey. Results Children with JIA had significantly less total sleep time, lower sleep efficiency (SE), and longer naps than TD children. Parents of children with JIA had significantly earlier bedtimes, more wake after sleep onset (WASO) and lower SE than TD parents. Parent–child SE and WASO were interrelated in JIA dyads. Sleep hygiene practices were inconsistent in both groups of children. Conclusions Inadequate amounts of sleep and poor sleep quality were common in parent–child dyads. Early interventions to improve sleep duration and promote sleep hygiene practices may alleviate future sleep problems and improve parent and child well-being. PMID:26994855

  4. Medial olivocochlear function in children with poor speech-in-noise performance and language disorder.

    PubMed

    Rocha-Muniz, Caroline Nunes; Mamede Carvallo, Renata Mota; Schochat, Eliane

    2017-05-01

    Contralateral masking of transient-evoked otoacoustic emissions is a phenomenon that suggests an inhibitory effect of the olivocochlear efferent auditory pathway. Many studies have been inconclusive in demonstrating a clear connection between this system and a behavioral speech-in-noise listening skill. The purpose of this study was to investigate the activation of a medial olivocochlear (MOC) efferent in children with poor speech-in-noise (PSIN) performance and children with language impairment and PSIN (SLI + PSIN). Transient evoked otoacoustic emissions (TEOAEs) with and without contralateral white noise were tested in 52 children (between 6 and 12 years). These children were arranged in three groups: typical development (TD) (n = 25), PSIN (n = 14) and SLI + PSI (n = 13). PSIN and SLI + PSI groups presented reduced otoacoustic emission suppression in comparison with the TD group. Our finding suggests differences in MOC function among children with typical development and children with poor SIN and language problems. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. Working memory span in Persian-speaking children with speech sound disorders and normal speech development.

    PubMed

    Afshar, Mohamad Reza; Ghorbani, Ali; Rashedi, Vahid; Jalilevand, Nahid; Kamali, Mohamad

    2017-10-01

    The aim of this study was to compare working memory span in Persian-speaking preschool children with speech sound disorder (SSD) and their typically speaking peers. Additionally, the study aimed to examine Non-Word Repetition (NWR), Forward Digit Span (FDS) and Backward Digit Span (BDS) in four groups of children with varying severity levels of SSD. The participants in this study comprised 35 children with SSD and 35 typically developing (TD) children -matched for age and sex-as a control group. The participants were between the age range of 48 and 72 months. Two components of working memory including phonological loop and central executive were compared between two groups. We used two tasks (NWR and FDS) to assess phonological loop component, and one task (BDS) to assess central executive component. Percentage of correct consonants (PCC) was used to calculate the severity of SSD. Significant differences were observed between the two groups in all tasks that assess working memory (p < 0.001). In addition, the comparison of the phonological loop of working memory between the various severity groups indicated significant differences between different severities of both NWR and FDS tasks among the SSD children (p < 0.001). Nevertheless, comparison of the central executive between various severity groups, which was assessed with the BDS task, did not show any significant differences (p > 0.05). The result showed that PCC scores in TD children were associated with NWR (p < 0.001), FDS (p = 0.001), and BDS (p < 0.001). Furthermore, PCC scores in SSD children were associated with NWR and FDS (p < 0.001), but not with BDS (p > 0.05). The working memory skills were weaker in SSD children, in comparison to TD children. In addition, children with varying levels of severity of SSD differed in terms of NWR and FSD, but not BDS. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. An investigation into the relationship between vigabatrin, movement disorders, and brain magnetic resonance imaging abnormalities in children with infantile spasms.

    PubMed

    Fong, Choong Yi; Osborne, John P; Edwards, Stuart W; Hemingway, Cheryl; Hancock, Eleanor; Johnson, Anthony L; Kennedy, Colin R; Kneen, Rachel; Likeman, Marcus; Lux, Andrew L; Mordekar, Santosh R; Murugan, Velayutham; Newton, Richard W; Pike, Michael; Quinn, Michael; Spinty, Stefan; Vassallo, Grace; Verity, Christopher M; Whitney, Andrea; O'Callaghan, Finbar J K

    2013-09-01

    We aimed to investigate the relationship between movement disorders, changes on brain magnetic resonance imaging (MRI), and vigabatrin therapy in children with infantile spasms. Retrospective review and brain MRI analysis of children enrolled in the International Collaborative Infantile Spasms Study (ICISS) who developed a movement disorder on vigabatrin therapy. Comparisons were made with controls within ICISS who had no movement disorder. Ten of 124 infants had a movement disorder and in eight it had developed on vigabatrin therapy. Two had a movement disorder that resolved on dose-reduction of vigabatrin, one had improvement on withdrawing vigabatrin, two had resolution without any dose change, and in three it persisted despite vigabatrin withdrawal. The typical brain MRI changes associated with vigabatrin therapy were noted in two infants. Ten control infants were identified. Typical MRI changes noted with vigabatrin were noted in three controls. It is possible that in two out of eight cases, vigabatrin was associated with the development of a movement disorder. In six out of eight cases a causal relationship was less plausible. The majority of infants treated with vigabatrin did not develop a movement disorder. MRI changes associated with vigabatrin do not appear to be specifically related to the movement disorder. © 2013 Mac Keith Press.

  7. Children's inequity aversion depends on culture: a cross-cultural comparison.

    PubMed

    Paulus, Markus

    2015-04-01

    Recent work showed the presence of strong forms of inequity aversion in young children. When presented with an uneven number of items, children would rather tend to throw one item away than to distribute them unequally between two anonymous others. The current study examined whether or not this pattern is a universal part of typical development by investigating 6- and 7-year-old Ugandan children. Results revealed that the Ugandan children, in contrast to their U.S. peers, tended to distribute the resources unequally rather than to throw the remaining resource away. This points to cross-cultural differences in the development of children's fairness-related decision making. Copyright © 2014 Elsevier Inc. All rights reserved.

  8. Latent energy storage with salt and metal mixtures for solar dynamic applications

    NASA Technical Reports Server (NTRS)

    Crane, R. A.; Konstantinou, K. S.

    1988-01-01

    This paper examines three design alternatives for the development of a solar dynamic heat receiver as applied to power systems operating in low earth orbit. These include a base line design used for comparison in ongoing NASA studies, a system incorporating a salt energy storage system with the salt dispersed within a metal mesh and a hybrid system incorporating both a molten salt and molten metal for energy storage. Based on a typical low earth orbit condition, designs are developed and compared to determine the effect of resultant conductivity, heat capacity and heat of fusion on system size, weight, temperature gradients, cycle turbine inlet temperature and material utilization.

  9. A Comparison of Deaf and Hearing Children's Reading Comprehension Profiles

    ERIC Educational Resources Information Center

    Kyle, Fiona E.; Cain, Kate

    2015-01-01

    Purpose: Although deaf children typically exhibit severe delays in reading achievement, there is a paucity of research looking at their text-level comprehension skills. We present a comparison of deaf and normally hearing readers' profiles on a commonly used reading comprehension assessment: the Neale Analysis of Reading Ability II. Methods:…

  10. Kinematic analysis of articulatory coupling in acquired apraxia of speech post-stroke.

    PubMed

    Bartle-Meyer, Carly J; Goozée, Justine V; Murdoch, Bruce E; Green, Jordan R

    2009-02-01

    Electromagnetic articulography was employed to investigate the strength of articulatory coupling and hence the degree of functional movement independence between individual articulators in apraxia of speech (AOS). Tongue-tip, tongue-back and jaw movement was recorded from five speakers with AOS and a concomitant aphasia (M = 53.6 years; SD = 12.60) during /ta, sa, la, ka/ syllable repetitions, spoken at typical and fast rates of speech. Covariance values were calculated for each articulatory pair to gauge the strength of articulatory coupling. The results obtained for each of the participants with AOS were individually compared to those obtained by a control group (n = 12; M = 52.08 years; SD = 12.52). Comparisons were made between the typical rate productions of the control group and the typical and fast rate productions of the participants with AOS. In comparison to the control group, four speakers with AOS exhibited significantly stronger articulatory coupling for alveolar and/or velar speech targets, during typical and/or fast rate conditions, suggesting decreased functional movement independence. The reduction in functional movement independence might have reflected an attempt to simplify articulatory control or a decrease in the ability to differentially control distinct articulatory regions.

  11. Impact of Nocturnal Low-Level Jets on Near-Surface Turbulence Kinetic Energy

    NASA Astrophysics Data System (ADS)

    Duarte, Henrique F.; Leclerc, Monique Y.; Zhang, Gengsheng; Durden, David; Kurzeja, Robert; Parker, Matthew; Werth, David

    2015-09-01

    We report on the role of low-level jets (LLJs) on the modulation of near-surface turbulence in the stable boundary layer, focusing on the behaviour of the transport terms of the turbulence kinetic energy (TKE) budget. We also examine the applicability of Monin-Obukhov similarity theory (MOST) in light of these terms. Using coincident near-surface turbulence and LLJ data collected over a three-month period in South Carolina, USA, we found that turbulence during LLJ periods was typically stronger and more well-developed in comparison with periods without a LLJ. We found a local imbalance in the near-surface TKE budget, in which the imbalance (residual) term was typically positive (i.e., energy gain) and nearly in equilibrium with buoyant consumption. Based on a comparison with previous studies, we assume that this residual term represents mostly pressure transport. We found the behaviour of the residual term to be better delineated in the presence of LLJs. We found shear production to adhere to MOST remarkably well during LLJs, except under very stable conditions. Gain of non-local TKE via pressure transport, likely consisting of large-scale fluctuations, could be the cause of the observed deviation from the MOST -less prediction. The fact that this deviation was observed for periods with well-developed turbulence with an inertial subrange slope close to indicates that such Kolmogorov turbulence is not a sufficient condition to guarantee the applicability of the MOST -less concept, as recently suggested in the literature. The implications of these results are discussed.

  12. Child-rearing in the context of childhood cancer: perspectives of parents and professionals.

    PubMed

    Long, Kristin A; Keeley, Lauren; Reiter-Purtill, Jennifer; Vannatta, Kathryn; Gerhardt, Cynthia A; Noll, Robert B

    2014-02-01

    Elevated distress has been well documented among parents of children with cancer. Family systems theories suggest that cancer-related stressors and parental distress have the potential to affect child-rearing practices, but this topic has received limited empirical attention. The present work examined self-reported child-rearing practices among mothers and fathers of children with cancer and matched comparisons. Medical and psychosocial professionals with expertise in pediatric oncology selected items from the Child-Rearing Practices Report (CRPR) likely to differentiate parents of children with cancer from matched comparison parents. Then, responses on these targeted items were compared between parents of children with cancer (94 mothers, 67 fathers) and matched comparisons (98 mothers, 75 fathers). Effect sizes of between-group differences were compared for mothers versus fathers. Pediatric oncology healthcare providers predicted that 14 items would differentiate child-rearing practices of parents of children with cancer from parents of typically developing children. Differences emerged on six of the 14 CRPR items. Parents of children with cancer reported higher levels of spoiling and concern about their child's health and development than comparison parents. Items assessing overprotection and emotional responsiveness did not distinguish the two groups of parents. The effect size for the group difference between mothers in the cancer versus comparison groups was significantly greater than that for fathers on one item related to worry about the child's health. Parents of children with cancer report differences in some, but not all, domains of child-rearing, as predicted by healthcare professionals. © 2013 Wiley Periodicals, Inc.

  13. Risk Evaluation in the Pre-Phase A Conceptual Design of Spacecraft

    NASA Technical Reports Server (NTRS)

    Fabisinski, Leo L., III; Maples, Charlotte Dauphne

    2010-01-01

    Typically, the most important decisions in the design of a spacecraft are made in the earliest stages of its conceptual design the Pre-Phase A stages. It is in these stages that the greatest number of design alternatives is considered, and the greatest number of alternatives is rejected. The focus of Pre-Phase A conceptual development is on the evaluation and comparison of whole concepts and the larger-scale systems comprising those concepts. This comparison typically uses general Figures of Merit (FOMs) to quantify the comparative benefits of designs and alternative design features. Along with mass, performance, and cost, risk should be one of the major FOMs in evaluating design decisions during the conceptual design phases. However, risk is often given inadequate consideration in conceptual design practice. The reasons frequently given for this lack of attention to risk include: inadequate mission definition, lack of rigorous design requirements in early concept phases, lack of fidelity in risk assessment methods, and under-evaluation of risk as a viable FOM for design evaluation. In this paper, the role of risk evaluation in early conceptual design is discussed. The various requirements of a viable risk evaluation tool at the Pre-Phase A level are considered in light of the needs of a typical spacecraft design study. A technique for risk identification and evaluation is presented. The application of the risk identification and evaluation approach to the conceptual design process is discussed. Finally, a computational tool for risk profiling is presented and applied to assess the risk for an existing Pre-Phase A proposal. The resulting profile is compared to the risks identified for the proposal by other means.

  14. Modelling Unsteady Wall Pressures Beneath Turbulent Boundary Layers

    NASA Technical Reports Server (NTRS)

    Ahn, B-K.; Graham, W. R.; Rizzi, S. A.

    2004-01-01

    As a structural entity of turbulence, hairpin vortices are believed to play a major role in developing and sustaining the turbulence process in the near wall region of turbulent boundary layers and may be regarded as the simplest conceptual model that can account for the essential features of the wall pressure fluctuations. In this work we focus on fully developed typical hairpin vortices and estimate the associated surface pressure distributions and their corresponding spectra. On the basis of the attached eddy model, we develop a representation of the overall surface pressure spectra in terms of the eddy size distribution. Instantaneous wavenumber spectra and spatial correlations are readily derivable from this representation. The model is validated by comparison of predicted wavenumber spectra and cross-correlations with existing emperical models and experimental data.

  15. A comparison of two colorimetric assays, based upon Lowry and Bradford techniques, to estimate total protein in soil extracts.

    PubMed

    Redmile-Gordon, M A; Armenise, E; White, R P; Hirsch, P R; Goulding, K W T

    2013-12-01

    Soil extracts usually contain large quantities of dissolved humified organic material, typically reflected by high polyphenolic content. Since polyphenols seriously confound quantification of extracted protein, minimising this interference is important to ensure measurements are representative. Although the Bradford colorimetric assay is used routinely in soil science for rapid quantification protein in soil-extracts, it has several limitations. We therefore investigated an alternative colorimetric technique based on the Lowry assay (frequently used to measure protein and humic substances as distinct pools in microbial biofilms). The accuracies of both the Bradford assay and a modified Lowry microplate method were compared in factorial combination. Protein was quantified in soil-extracts (extracted with citrate), including standard additions of model protein (BSA) and polyphenol (Sigma H1675-2). Using the Lowry microplate assay described, no interfering effects of citrate were detected even with concentrations up to 5 times greater than are typically used to extract soil protein. Moreover, the Bradford assay was found to be highly susceptible to two simultaneous and confounding artefacts: 1) the colour development due to added protein was greatly inhibited by polyphenol concentration, and 2) substantial colour development was caused directly by the polyphenol addition. In contrast, the Lowry method enabled distinction between colour development from protein and non-protein origin, providing a more accurate quantitative analysis. These results suggest that the modified-Lowry method is a more suitable measure of extract protein (defined by standard equivalents) because it is less confounded by the high polyphenolic content which is so typical of soil extracts.

  16. Adaptive behaviour in children and adolescents with foetal alcohol spectrum disorders: a comparison with specific learning disability and typical development

    PubMed Central

    Autti-Rämö, Ilona; Kalland, Mirjam; Santtila, Pekka; Hoyme, H. Eugene; Mattson, Sarah N.; Korkman, Marit

    2013-01-01

    Foetal alcohol spectrum disorders (FASD) is a leading cause of intellectual disability in the western world. Children and adolescents with FASD are often exposed to a double burden in life, as their neurological sequelae are accompanied by adverse living surroundings exposing them to further environmental risk. In the present study, the adaptive abilities of a group of children and adolescents with FASD were examined using the Vineland Adaptive Behaviour Scales (VABS) and compared to those of a group of IQ-matched children with specific learning disorder (SLD) as well as with typically developing controls (CON). The results showed significantly different adaptive abilities among the groups: Children with FASD performed worse than IQ-matched children with SLD, who in turn performed worse than typically developing children on all domains (communication, daily living skills and socialization) on the VABS. Compared to the other groups, social skills declined with age in the FASD group. These results support previous studies of adaptive behaviour deficits in children with FASD and provide further evidence of the specificity of these deficits. On a societal level, more efforts and resources should be focused on recognizing and diagnosing FASD and supporting communication skills, daily living skills and most of all social skills across diagnostic groups within FASD. Without adequate intervention, adolescents and young adults with FASD run a great risk of marginalization and social maladjustment, costly not only to society but also to the lives of the many young people with FASD. PMID:22358422

  17. Charting the life course: age differences and validity of beliefs about lifespan development.

    PubMed

    Riediger, Michaela; Voelkle, Manuel C; Schaefer, Sabine; Lindenberger, Ulman

    2014-09-01

    This study examined how children (9 years), adolescents (13 to 15 years), younger adults (21 to 26 years), and older adults (70 to 76 years) chart age gradients of cognitive and social functioning from childhood to old age. Participants (N = 156) rated typical performance levels in different life phases for 10 aspects of cognitive and social functioning. Compared with older participants, children expected lower performance levels and higher temporal stability, particularly during adulthood and into old age, and showed lower interindividual consensus in their ratings. Individuals in all 4 age groups recognized that fluid cognitive abilities reach their developmental peak earlier in life and decline more steeply thereafter than crystallized cognitive abilities. Older adults and, to a lesser extent, children evaluated their own current functioning as being better than that of their typical age peers. Furthermore, older adults charted typical cognitive development in middle and earlier late adulthood more positively than the participants in the other 3 age groups, which possibly reflects a partial externalization of their own positive self-views and a self-enhancing bias. Comparisons with life span gradients of cognitive performance (McArdle, Ferrer-Caja, Hamagami, & Woodcock, 2002) suggest that the ratings of adolescents and younger adults were in better agreement with empirically observed average performance trajectories than the ratings of children and older adults. We conclude that beliefs about normative cognitive and social aspects of life span development emerge in late middle childhood, solidify into culturally shared scripts by mid-adolescence, and remain subject to further change into old age. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  18. Delay of gratification: a comparison study of children with Down syndrome, moderate intellectual disability and typical development.

    PubMed

    Cuskelly, M; Gilmore, L; Glenn, S; Jobling, A

    2016-09-01

    Self-regulation has been found to be an important contributor to a range of outcomes, with delay of gratification (a self-regulatory skill) predicting better academic, social and personal functioning. There is some evidence that individuals with Down syndrome have difficulty with delay of gratification. We investigated the question of whether this difficulty is common to intellectual disability irrespective of aetiology, or whether it presents a particular problem for those with Down syndrome. The latter was considered a possibility because of language difficulties in this group. Three groups of children with a mean MA between 36 and 60 months participated in the study: children with Down syndrome (n = 32), children with a moderate intellectual disability from a cause other than Down syndrome (n = 26) and typically developing children (n = 50). Children completed a series of measures of language and cognitive functioning and participated in a delay of gratification task. The group of children with Down syndrome delayed for a significantly shorter time than either of the other two groups that did not differ from each other. Receptive language was associated with delay time for the children with Down syndrome but not for the typically developing group, nor for the group with moderate intellectual disability. Children with Down syndrome appear to have a particular difficulty with delay of gratification. Language abilities would seem to be implicated in this difficulty, although further examination of this hypothesis is required. © 2016 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

  19. Driving Comparisons Between Young Adults with Autism Spectrum Disorder and Typical Development.

    PubMed

    Patrick, Kristina E; Hurewitz, Felicia; McCurdy, Mark D; Agate, Frederic Taylor; Daly, Brian P; Tarazi, Reem A; Chute, Douglas L; Schultheis, Maria T

    2018-05-18

    Many individuals with autism spectrum disorder (ASD) are reluctant to pursue driving because of concerns about their ability to drive safely. This study aimed to assess differences in simulated driving performance in young adults with ASD and typical development, examining relationships between driving performance and the level of experience (none, driver's permit, licensed) across increasingly difficult driving environments. Participants included 50 English-speaking young adults (16-26 years old) with ASD matched for sex, age, and licensure with 50 typically-developing (TD) peers. Participants completed a structured driving assessment using a virtual-reality simulator that included increasingly complex environmental demands. Differences in mean speed and speed and lane variability by diagnostic group and driving experience were analyzed using multilevel linear modeling. Young adults with ASD demonstrated increased variability in speed and lane positioning compared with controls, even during low demand tasks. When driving demands became more complex, group differences were moderated by driving experience such that licensed drivers with ASD drove similarly to TD licensed drivers for most tasks, whereas unlicensed drivers with ASD had more difficulty with speed and lane management than TD drivers. Findings suggest that young adults with ASD may have more difficulty with basic driving skills than peers, particularly in the early stages of driver training. Increased difficulty compared with peers increases as driving demands become more complex, suggesting that individuals with ASD may benefit from a slow and gradual approach to driver training. Future studies should evaluate predictors of driving performance, on-road driving, and ASD-specific driving interventions.

  20. A comparison of postnatal arterial patterns in a growth series of giraffe (Artiodactyla: Giraffa camelopardalis)

    PubMed Central

    Gignac, Paul M.; Hieronymus, Tobin L.; Witmer, Lawrence M.

    2016-01-01

    Nearly all living artiodactyls (even-toed ungulates) possess a derived cranial arterial pattern that is highly distinctive from most other mammals. Foremost among a suite of atypical arterial configurations is the functional and anatomical replacement of the internal carotid artery with an extensive, subdural arterial meshwork called the carotid rete. This interdigitating network branches from the maxillary artery and is housed within the cavernous venous sinus. As the cavernous sinus receives cooled blood draining from the nasal mucosa, heat rapidly dissipates across the high surface area of the rete to be carried away from the brain by the venous system. This combination yields one of the most effective mechanisms of selective brain cooling. Although arterial development begins from the same embryonic scaffolding typical of mammals, possession of a rete is typically accompanied by obliteration of the internal carotid artery. Among taxa with available ontogenetic data, the point at which the internal carotid obliterates is variable throughout development. In small-bodied artiodactyls, the internal carotid typically obliterates prior to parturition, but in larger species, the vessel may remain patent for several years. In this study, we use digital anatomical data collection methods to describe the cranial arterial patterns for a growth series of giraffe (Giraffa camelopardalis), from parturition to senescence. Giraffes, in particular, have unique cardiovascular demands and adaptations owing to their exceptional body form and may not adhere to previously documented stages of cranial arterial development. We find the carotid arterial system to be conserved between developmental stages and that obliteration of the giraffe internal carotid artery occurs prior to parturition. PMID:26925324

  1. Preschool predictors of mathematics in first grade children with autism spectrum disorder.

    PubMed

    Titeca, Daisy; Roeyers, Herbert; Josephy, Haeike; Ceulemans, Annelies; Desoete, Annemie

    2014-11-01

    Up till now, research evidence on the mathematical abilities of children with autism spectrum disorder (ASD) has been scarce and provided mixed results. The current study examined the predictive value of five early numerical competencies for four domains of mathematics in first grade. Thirty-three high-functioning children with ASD were followed up from preschool to first grade and compared with 54 typically developing children, as well as with normed samples in first grade. Five early numerical competencies were tested in preschool (5-6 years): verbal subitizing, counting, magnitude comparison, estimation, and arithmetic operations. Four domains of mathematics were used as outcome variables in first grade (6-7 years): procedural calculation, number fact retrieval, word/language problems, and time-related competences. Children with ASD showed similar early numerical competencies at preschool age as typically developing children. Moreover, they scored average on number fact retrieval and time-related competences and higher on procedural calculation and word/language problems compared to the normed population in first grade. When predicting first grade mathematics performance in children with ASD, both verbal subitizing and counting seemed to be important to evaluate at preschool age. Verbal subitizing had a higher predictive value in children with ASD than in typically developing children. Whereas verbal subitizing was predictive for procedural calculation, number fact retrieval, and word/language problems, counting was predictive for procedural calculation and, to a lesser extent, number fact retrieval. Implications and directions for future research are discussed. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  2. A comparison of postnatal arterial patterns in a growth series of giraffe (Artiodactyla: Giraffa camelopardalis).

    PubMed

    O'Brien, Haley D; Gignac, Paul M; Hieronymus, Tobin L; Witmer, Lawrence M

    2016-01-01

    Nearly all living artiodactyls (even-toed ungulates) possess a derived cranial arterial pattern that is highly distinctive from most other mammals. Foremost among a suite of atypical arterial configurations is the functional and anatomical replacement of the internal carotid artery with an extensive, subdural arterial meshwork called the carotid rete. This interdigitating network branches from the maxillary artery and is housed within the cavernous venous sinus. As the cavernous sinus receives cooled blood draining from the nasal mucosa, heat rapidly dissipates across the high surface area of the rete to be carried away from the brain by the venous system. This combination yields one of the most effective mechanisms of selective brain cooling. Although arterial development begins from the same embryonic scaffolding typical of mammals, possession of a rete is typically accompanied by obliteration of the internal carotid artery. Among taxa with available ontogenetic data, the point at which the internal carotid obliterates is variable throughout development. In small-bodied artiodactyls, the internal carotid typically obliterates prior to parturition, but in larger species, the vessel may remain patent for several years. In this study, we use digital anatomical data collection methods to describe the cranial arterial patterns for a growth series of giraffe (Giraffa camelopardalis), from parturition to senescence. Giraffes, in particular, have unique cardiovascular demands and adaptations owing to their exceptional body form and may not adhere to previously documented stages of cranial arterial development. We find the carotid arterial system to be conserved between developmental stages and that obliteration of the giraffe internal carotid artery occurs prior to parturition.

  3. The expression and understanding of jealousy in children with autism.

    PubMed

    Bauminger, Nirit

    2004-01-01

    We investigated the expression and understanding of jealousy in 16 high-functioning children with autism and 17 typically developing children matched for IQ, chronological age, gender, and maternal education. We examined the expression of jealousy via children's behaviors, verbalizations, and affects demonstrated during two jealousy-provoking triadic scenarios (drawing and playing) enacted among the child in the experimental group (autism or typical), that child's main caregiver (mostly mothers), and a familiar peer or sibling. The two scenarios corresponded with the two types of jealousy described in past studies: social-comparison jealousy (drawing scenario) and social-relational jealousy (playing scenario). To tap children's understanding, we asked them to identify jealousy from a picture, to provide examples of times they felt jealous, and to offer suggestions for coping with jealousy. The main results revealed that children with autism expressed jealousy in situations similar to their typical age mates but manifested it in different behaviors. Moreover, children with autism revealed a less coherent understanding of the feeling. We discuss the meaning of the gap between demonstrating and understanding jealousy in light of the two central theoretical views conceptualizing the core emotional deficit in children with autism.

  4. RAINBOW TROUT ANDROGEN RECEPTOR ALPHA AND THE HUMAN ANDROGEN RECEPTOR: COMPARISONS IN THE COS WHOLE CELL BINDING ASSAY

    EPA Science Inventory

    RAINBOW TROUT ANDROGEN RECEPTOR ALPHA AND HUMAN ANDROGEN RECEPTOR: COMPARISONS IN THE COS WHOLE CELL BINDING ASSAY.
    MC Cardon, PC Hartig,LE Gray, Jr. and VS Wilson.
    U.S. EPA, ORD, NHEERL, RTD, Research Triangle Park, NC, USA.
    Typically, in vitro hazard assessments for ...

  5. [Index of Nutritional Purchasing Power Parity: comparison of caloric costs of a healthy versus an unhealthy diet].

    PubMed

    Mendoza Velázquez, Alfonso

    2012-01-01

    Develop the Index of Nutritional Purchasing Power Parity (Nut3-CiO) as an instrument to compare the caloric costs of a healthy versus an unhealthy diet between regions or cities in a country over time. Indices of caloric prices were constructed and the "law of one price" was used to derive the Nut3-CiO index. Caloric inflation rates were obtained using basic descriptive statistics. The Nut3-CiO was applied in the major cities of Mexico during the period from January 1996 to December 2010. The statistical behavior of the Nut3-CiO revealed that, in Mexican cities, products for a typical diet are less expensive than products for a healthy diet. The findings showed a cyclical behavior to the index, a high correlation between inflation for the typical diet and inflation for the market basket, and a high persistence of prices. The Nut3-CiO index makes it possible to periodically compare the price differential of two types of diets-typical and healthy-between cities in a single country. This instrument could help health authorities identify the cities where it is easier or more difficult for consumers to access a typical or healthy diet in terms of cost. Furthermore, it makes it possible to estimate the percentage adjustment necessary in each city to attain levels of nutritional purchasing power parity.

  6. Interstitial hyperthermia treatment of countercurrent vascular tissue: a comparison of Pennes, WJ and porous media bioheat models.

    PubMed

    Hassanpour, Saied; Saboonchi, Ahmad

    2014-12-01

    Development of appropriate heat transfer models to investigate the thermal behavior of living tissues has become increasingly important in simulations of cancer hyperthermia. In this paper, a review is initially presented of the more important general models developed for heat transfer description of perfused tissues. Comparisons are then made between Pennes' simplified Weinbaum and Jiji "WJ" and the more recent porous media "PM" bioheat models. For this purpose, a mathematical model is developed for the heat transfer in a cylindrical medium containing parallel counter-current pairs of small vessels with characteristics as much as possible similar to those of living tissues. The validity of the models is examined and confirmed using the Pennes in vivo experiments and one-dimensional analytical solutions. For consideration of interstitial hyperthermia treatment the smaller cylindrical zone with typical heat generation, is assumed in the center of the main cylinder. The numerical simulation results revealed that, despite difference in temperature distributions calculated by these three models at normal condition, the heat affected zone at hyperthermic condition predicted by all three models are similar. Copyright © 2014 Elsevier Ltd. All rights reserved.

  7. Large Scale Flood Risk Analysis using a New Hyper-resolution Population Dataset

    NASA Astrophysics Data System (ADS)

    Smith, A.; Neal, J. C.; Bates, P. D.; Quinn, N.; Wing, O.

    2017-12-01

    Here we present the first national scale flood risk analyses, using high resolution Facebook Connectivity Lab population data and data from a hyper resolution flood hazard model. In recent years the field of large scale hydraulic modelling has been transformed by new remotely sensed datasets, improved process representation, highly efficient flow algorithms and increases in computational power. These developments have allowed flood risk analysis to be undertaken in previously unmodeled territories and from continental to global scales. Flood risk analyses are typically conducted via the integration of modelled water depths with an exposure dataset. Over large scales and in data poor areas, these exposure data typically take the form of a gridded population dataset, estimating population density using remotely sensed data and/or locally available census data. The local nature of flooding dictates that for robust flood risk analysis to be undertaken both hazard and exposure data should sufficiently resolve local scale features. Global flood frameworks are enabling flood hazard data to produced at 90m resolution, resulting in a mis-match with available population datasets which are typically more coarsely resolved. Moreover, these exposure data are typically focused on urban areas and struggle to represent rural populations. In this study we integrate a new population dataset with a global flood hazard model. The population dataset was produced by the Connectivity Lab at Facebook, providing gridded population data at 5m resolution, representing a resolution increase over previous countrywide data sets of multiple orders of magnitude. Flood risk analysis undertaken over a number of developing countries are presented, along with a comparison of flood risk analyses undertaken using pre-existing population datasets.

  8. Food packages for Space Shuttle

    NASA Technical Reports Server (NTRS)

    Fohey, M. F.; Sauer, R. L.; Westover, J. B.; Rockafeller, E. F.

    1978-01-01

    The paper reviews food packaging techniques used in space flight missions and describes the system developed for the Space Shuttle. Attention is directed to bite-size food cubes used in Gemini, Gemini rehydratable food packages, Apollo spoon-bowl rehydratable packages, thermostabilized flex pouch for Apollo, tear-top commercial food cans used in Skylab, polyethylene beverage containers, Skylab rehydratable food package, Space Shuttle food package configuration, duck-bill septum rehydration device, and a drinking/dispensing nozzle for Space Shuttle liquids. Constraints and testing of packaging is considered, a comparison of food package materials is presented, and typical Shuttle foods and beverages are listed.

  9. Automation of the Image Analysis for Thermographic Inspection

    NASA Technical Reports Server (NTRS)

    Plotnikov, Yuri A.; Winfree, William P.

    1998-01-01

    Several data processing procedures for the pulse thermal inspection require preliminary determination of an unflawed region. Typically, an initial analysis of the thermal images is performed by an operator to determine the locations of unflawed and the defective areas. In the present work an algorithm is developed for automatically determining a reference point corresponding to an unflawed region. Results are obtained for defects which are arbitrarily located in the inspection region. A comparison is presented of the distributions of derived values with right and wrong localization of the reference point. Different algorithms of automatic determination of the reference point are compared.

  10. Advanced subsonic long-haul transport terminal area compatibility study. Volume 1: Compatibility assessment

    NASA Technical Reports Server (NTRS)

    1974-01-01

    An analysis was made to identify airplane research and technology necessary to ensure advanced transport aircraft the capability of accommodating forecast traffic without adverse impact on airport communities. Projections were made of the delay, noise, and emissions impact of future aircraft fleets on typical large urban airport. Design requirements, based on these projections, were developed for an advanced technology, long-haul, subsonic transport. A baseline aircraft was modified to fulfill the design requirements for terminal area compatibility. Technical and economic comparisons were made between these and other aircraft configured to support the study.

  11. Research of the application of the Low Power Wide Area Network in power grid

    NASA Astrophysics Data System (ADS)

    Wang, Hao; Sui, Hong; Li, Jia; Yao, Jian

    2018-03-01

    Low Power Wide Area Network (LPWAN) technologies developed rapidly in recent years, but these technologies have not make large-scale applications in different application scenarios of power grid. LoRa is a mainstream LPWAN technology. This paper makes a comparison test of the signal coverage of LoRa and other traditional wireless communication technologies in typical signal environment of power grid. Based on the test results, this paper gives an application suggestion of LoRa in power grid services, which can guide the planning and construction of the LPWAN in power grid.

  12. Complex Molecules in the Laboratory - a Comparison of Chriped Pulse and Emission Spectroscopy

    NASA Astrophysics Data System (ADS)

    Hermanns, Marius; Wehres, Nadine; Maßen, Jakob; Schlemmer, Stephan

    2017-06-01

    Detecting molecules of astrophysical interest in the interstellar medium strongly relies on precise spectroscopic data from the laboratory. In recent years, the advancement of the chirped-pulse technique has added many more options available to choose from. The Cologne emission spectrometer is an additional path to molecular spectroscopy. It allows to record instantaneously broad band spectra with calibrated intensities. Here we present a comparison of both methods: The Cologne chirped-pulse spectrometer as well as the Cologne emission spectrometer both cover the frequency range of 75-110 GHz, consistent with the ALMA Band 3 receivers. High sensitive heterodyne receivers with very low noise temperature amplifiers are used with a typical bandwidth of 2.5 GHz in a single sideband. Additionally the chirped-pulse spectrometer contains a high power amplifier of 200 mW for the excitation of molecules. Room temperature spectra of methyl cyanide and comparison of key features, such as measurement time, sensitivity, limitations and commonalities are shown in respect to identification of complex molecules of astrophysical importance. In addition, future developments for both setups will be discussed.

  13. Comparison of typical mega cities in China using emergy synthesis

    NASA Astrophysics Data System (ADS)

    Zhang, L. X.; Chen, B.; Yang, Z. F.; Chen, G. Q.; Jiang, M. M.; Liu, G. Y.

    2009-06-01

    An emergy-based comparison analysis is conducted for three typical mega cities in China, i.e., Beijing, Shanghai and Guangzhou, from 1990 to 2005 in four perspectives including emergy intensity, resource structure, environmental pressure and resource use efficiency. A new index of non-renewable emergy/money ratio is established to indicate the utilization efficiency of the non-renewable resources. The results show that for the three mega urban systems, Beijing, Shanghai and Guangzhou, the total emergy inputs were 3.76E+23, 3.54E+23, 2.52E+23 sej in 2005, of which 64.88%, 91.45% and 72.28% were imported from the outsides, respectively. As to the indicators of emergy intensity involving the total emergy use, emergy density and emergy use per cap, three cities exhibited similar overall increase trends with annual fluctuations from 1990 to 2005. Shanghai achieved the highest level of economic development and non-renewable resource use efficiency, and meanwhile, lower proportion of renewable resource use and higher environmental pressure compared to those of Beijing and Guangzhou. Guangzhou has long term sustainability considering an amount of local renewable resources used, per capita emergy used, energy consumption per unit GDP and the ratio of waste to renewable emergy. It can be concluded that different emergy-based evaluation results arise from different geographical locations, resources endowments, industrial structures and urban orientations of the concerned mega cities.

  14. Development of high-speed balancing technology

    NASA Technical Reports Server (NTRS)

    Demuth, R.; Zorzi, E.

    1981-01-01

    An investigation into laser material removal showed that laser burns act in a manner typical of mechanical stress raisers causing a reduction in fatigue strength; the fatigue strength is lowered relative to the smooth specimen fatigue strength. Laser-burn zones were studied for four materials: Alloy Steel 4340, Stainless Steel 17-4 PH, Inconel 718, and Aluminum Alloy 6061-T6. Calculations were made of stress concentration factors K, for laser-burn grooves of each material type. A comparison was then made to experimentally determine the fatigue strength reduction factor. These calculations and comparisons indicated that, except for the 17-4 PH material, good agreement (a ratio of close to 1.0) existed between Kt and Kf. The performance of the 17-4 PH material has been attributed to early crack initiation due to the lower fatigue resistance of the soft, unaged laser-affected zone. Also covered in this report is the development, implementation, and testing of an influence coefficient approach to balancing a long, slender shaft under applied-torque conditions. Excellent correlation existed between the analytically predicted results and those data obtained from testing.

  15. Blood transcriptomic comparison of individuals with and without autism spectrum disorder: A combined-samples mega-analysis.

    PubMed

    Tylee, Daniel S; Hess, Jonathan L; Quinn, Thomas P; Barve, Rahul; Huang, Hailiang; Zhang-James, Yanli; Chang, Jeffrey; Stamova, Boryana S; Sharp, Frank R; Hertz-Picciotto, Irva; Faraone, Stephen V; Kong, Sek Won; Glatt, Stephen J

    2017-04-01

    Blood-based microarray studies comparing individuals affected with autism spectrum disorder (ASD) and typically developing individuals help characterize differences in circulating immune cell functions and offer potential biomarker signal. We sought to combine the subject-level data from previously published studies by mega-analysis to increase the statistical power. We identified studies that compared ex vivo blood or lymphocytes from ASD-affected individuals and unrelated comparison subjects using Affymetrix or Illumina array platforms. Raw microarray data and clinical meta-data were obtained from seven studies, totaling 626 affected and 447 comparison subjects. Microarray data were processed using uniform methods. Covariate-controlled mixed-effect linear models were used to identify gene transcripts and co-expression network modules that were significantly associated with diagnostic status. Permutation-based gene-set analysis was used to identify functionally related sets of genes that were over- and under-expressed among ASD samples. Our results were consistent with diminished interferon-, EGF-, PDGF-, PI3K-AKT-mTOR-, and RAS-MAPK-signaling cascades, and increased ribosomal translation and NK-cell related activity in ASD. We explored evidence for sex-differences in the ASD-related transcriptomic signature. We also demonstrated that machine-learning classifiers using blood transcriptome data perform with moderate accuracy when data are combined across studies. Comparing our results with those from blood-based studies of protein biomarkers (e.g., cytokines and trophic factors), we propose that ASD may feature decoupling between certain circulating signaling proteins (higher in ASD samples) and the transcriptional cascades which they typically elicit within circulating immune cells (lower in ASD samples). These findings provide insight into ASD-related transcriptional differences in circulating immune cells. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  16. Blood Transcriptomic Comparison of Individuals with and without Autism Spectrum Disorder: A Combined-Samples Mega-Analysis

    PubMed Central

    Tylee, Daniel S.; Hess, Jonathan L.; Quinn, Thomas P.; Barve, Rahul; Huang, Hailiang; Zhang-James, Yanli; Chang, Jeffrey; Stamova, Boryana S.; Sharp, Frank R.; Hertz-Picciotto, Irva; Faraone, Stephen V.; Kong, Sek Won; Glatt, Stephen J.

    2017-01-01

    Blood-based microarray studies comparing individuals affected with autism spectrum disorder (ASD) and typically developing individuals help characterize differences in circulating immune cell functions and offer potential biomarker signal. We sought to combine the subject-level data from previously published studies by mega-analysis to increase the statistical power. We identified studies that compared ex-vivo blood or lymphocytes from ASD-affected individuals and unrelated comparison subjects using Affymetrix or Illumina array platforms. Raw microarray data and clinical meta-data were obtained from seven studies, totaling 626 affected and 447 comparison subjects. Microarray data were processed using uniform methods. Covariate-controlled mixed-effect linear models were used to identify gene transcripts and co-expression network modules that were significantly associated with diagnostic status. Permutation-based gene-set analysis was used to identify functionally related sets of genes that were over- and under-expressed among ASD samples. Our results were consistent with diminished interferon-, EGF-, PDGF-, PI3K-AKT-mTOR-, and RAS-MAPK-signaling cascades, and increased ribosomal translation and NK-cell related activity in ASD. We explored evidence for sex-differences in the ASD-related transcriptomic signature. We also demonstrated that machine-learning classifiers using blood transcriptome data perform with moderate accuracy when data are combined across studies. Comparing our results with those from blood-based studies of protein biomarkers (e.g., cytokines and trophic factors), we propose that ASD may feature decoupling between certain circulating signaling proteins (higher in ASD samples) and the transcriptional cascades which they typically elicit within circulating immune cells (lower in ASD samples). These findings provide insight into ASD-related transcriptional differences in circulating immune cells. PMID:27862943

  17. Usability Operations on Touch Mobile Devices for Users with Autism.

    PubMed

    Quezada, Angeles; Juárez-Ramírez, Reyes; Jiménez, Samantha; Noriega, Alan Ramírez; Inzunza, Sergio; Garza, Arnulfo Alanis

    2017-10-14

    The Autistic Spectrum Disorder is a cognitive disorder that affects the cognitive and motor skills; due that, users cannot perform digital and fine motor tasks. It is necessary to create software applications that adapt to the abilities of these users. In recent years has been an increase in the research of the use of technology to support autistic users to develop their communication skills and to improve learning. However, the applications' usability for disable users is not assessed objectively as the existing models do not consider interaction operators for disable users. This article focuses on identifying the operations that can easily be performed by autistic users following the metrics of KML-GOMS, TLM and FLM. In addition, users of typical development were included in order to do a comparison between both types of users. The experiment was carried out using four applications designed for autistic users. Participants were subjects divided in two groups: level 1 and level 2 autistic users, and a group of users of typical development. During the experimentation, users performed a use case for each application; the time needed to perform each task was measured. Results show that the easiest operations for autistic users are K (Keystroke), D (Drag), Initial Act (I) and Tapping (T).

  18. Autism and family home movies: a comprehensive review.

    PubMed

    Palomo, Rubén; Belinchón, Mercedes; Ozonoff, Sally

    2006-04-01

    In this article, we focus on the early development of autism studied through family home movies. We review all investigations published in English that met specific methodological standards, including the use of comparison samples, coding blind to group membership, and adequate levels of interrater reliability. After discussing in detail the pros and cons of the home-movie methodology, we review the results of all empirical studies conducted to date. We then present a summary of the features found consistently across studies that differentiate autism from typical development and mental retardation in the first 2 years of life. How family home movies can contribute to our understanding of the regression phenomenon is also addressed. Finally, the results are interpreted from both a theoretical and clinical point of view.

  19. Interlaboratory comparison for the determination of the soluble fraction of metals in welding fume samples.

    PubMed

    Berlinger, Balazs; Harper, Martin

    2018-02-01

    There is interest in the bioaccessible metal components of aerosols, but this has been minimally studied because standardized sampling and analytical methods have not yet been developed. An interlaboratory study (ILS) has been carried out to evaluate a method for determining the water-soluble component of realistic welding fume (WF) air samples. Replicate samples were generated in the laboratory and distributed to participating laboratories to be analyzed according to a standardized procedure. Within-laboratory precision of replicate sample analysis (repeatability) was very good. Reproducibility between laboratories was not as good, but within limits of acceptability for the analysis of typical aerosol samples. These results can be used to support the development of a standardized test method.

  20. Moving in Parallel Toward a Modern Modeling Epistemology: Bayes Factors and Frequentist Modeling Methods.

    PubMed

    Rodgers, Joseph Lee

    2016-01-01

    The Bayesian-frequentist debate typically portrays these statistical perspectives as opposing views. However, both Bayesian and frequentist statisticians have expanded their epistemological basis away from a singular focus on the null hypothesis, to a broader perspective involving the development and comparison of competing statistical/mathematical models. For frequentists, statistical developments such as structural equation modeling and multilevel modeling have facilitated this transition. For Bayesians, the Bayes factor has facilitated this transition. The Bayes factor is treated in articles within this issue of Multivariate Behavioral Research. The current presentation provides brief commentary on those articles and more extended discussion of the transition toward a modern modeling epistemology. In certain respects, Bayesians and frequentists share common goals.

  1. A Method for the Comparison of Item Selection Rules in Computerized Adaptive Testing

    ERIC Educational Resources Information Center

    Barrada, Juan Ramon; Olea, Julio; Ponsoda, Vicente; Abad, Francisco Jose

    2010-01-01

    In a typical study comparing the relative efficiency of two item selection rules in computerized adaptive testing, the common result is that they simultaneously differ in accuracy and security, making it difficult to reach a conclusion on which is the more appropriate rule. This study proposes a strategy to conduct a global comparison of two or…

  2. Experiments with a Supersonic Multi-Channel Radial Diffuser.

    DTIC Science & Technology

    1980-09-01

    unlimited. 17 . DISTRIBUTION STATEMENT (o the *bsta~c entered nRItok 20, it dffttt Iton, Report) IS. SUPPLEMENTARY NOTES 19. KEY WORDS (Continue o...Improvements 17 VI SIGNIFICANT TEST RESULTS 20 1. General Considerations 20 2. Typical Radial Diffuser Performance 20 3. Flow Stability Experiments 22 VIII...Adjustments Indicated 39 16 Comparison of the Single Channel Performances for Two Extreme Channel Geometries 40 17 Typical Radial Diffuser Performance

  3. Source-term development for a contaminant plume for use by multimedia risk assessment models

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Whelan, Gene; McDonald, John P.; Taira, Randal Y.

    1999-12-01

    Multimedia modelers from the U.S. Environmental Protection Agency (EPA) and the U.S. Department of Energy (DOE) are collaborating to conduct a comprehensive and quantitative benchmarking analysis of four intermedia models: DOE's Multimedia Environmental Pollutant Assessment System (MEPAS), EPA's MMSOILS, EPA's PRESTO, and DOE's RESidual RADioactivity (RESRAD). These models represent typical analytically, semi-analytically, and empirically based tools that are utilized in human risk and endangerment assessments for use at installations containing radioactive and/or hazardous contaminants. Although the benchmarking exercise traditionally emphasizes the application and comparison of these models, the establishment of a Conceptual Site Model (CSM) should be viewed with equalmore » importance. This paper reviews an approach for developing a CSM of an existing, real-world, Sr-90 plume at DOE's Hanford installation in Richland, Washington, for use in a multimedia-based benchmarking exercise bet ween MEPAS, MMSOILS, PRESTO, and RESRAD. In an unconventional move for analytically based modeling, the benchmarking exercise will begin with the plume as the source of contamination. The source and release mechanism are developed and described within the context of performing a preliminary risk assessment utilizing these analytical models. By beginning with the plume as the source term, this paper reviews a typical process and procedure an analyst would follow in developing a CSM for use in a preliminary assessment using this class of analytical tool.« less

  4. Performance Comparison of EPICS IOC and MARTe in a Hard Real-Time Control Application

    NASA Astrophysics Data System (ADS)

    Barbalace, Antonio; Manduchi, Gabriele; Neto, A.; De Tommasi, G.; Sartori, F.; Valcarcel, D. F.

    2011-12-01

    EPICS is used worldwide mostly for controlling accelerators and large experimental physics facilities. Although EPICS is well fit for the design and development of automation systems, which are typically VME or PLC-based systems, and for soft real-time systems, it may present several drawbacks when used to develop hard real-time systems/applications especially when general purpose operating systems as plain Linux are chosen. This is in particular true in fusion research devices typically employing several hard real-time systems, such as the magnetic control systems, that may require strict determinism, and high performance in terms of jitter and latency. Serious deterioration of important plasma parameters may happen otherwise, possibly leading to an abrupt termination of the plasma discharge. The MARTe framework has been recently developed to fulfill the demanding requirements for such real-time systems that are alike to run on general purpose operating systems, possibly integrated with the low-latency real-time preemption patches. MARTe has been adopted to develop a number of real-time systems in different Tokamaks. In this paper, we first summarize differences and similarities between EPICS IOC and MARTe. Then we report on a set of performance measurements executed on an x86 64 bit multicore machine running Linux with an IO control algorithm implemented in an EPICS IOC and in MARTe.

  5. Young children's attitudes toward peers with intellectual disabilities: effect of the type of school.

    PubMed

    Georgiadi, Maria; Kalyva, Efrosini; Kourkoutas, Elias; Tsakiris, Vlastaris

    2012-11-01

    This study explored typically developing children's attitudes towards peers with intellectual disabilities, with special reference to the type of school they attended. Two hundred and fifty-six Greek children aged 9-10 (135 in inclusive settings) completed a questionnaire and an adjective list by Gash (European Journal of Special Needs Education 1993; 8, 106) and drew a child with intellectual disabilities, commenting also on their drawings. Typically developing children expressed overall neutral attitudes towards peers with intellectual disabilities. Type of school differentiated their attitudes, with children from inclusive settings being more positive towards peers with intellectual disabilities and choosing less negative adjectives to describe them than children from non-inclusive settings. Girls and students who expressed more positive social, emotional and overall attitudes towards students with intellectual disabilities chose more positive adjectives to describe a child with intellectual disabilities. It was also found that children from inclusive settings drew children with intellectual disabilities as more similar to a child with Down syndrome in comparison with children from non-inclusive settings. Effective inclusive practices should be promoted to foster social acceptance of students with intellectual disabilities. © 2012 Blackwell Publishing Ltd.

  6. A comparison of WISC-IV and SB-5 intelligence scores in adolescents with autism spectrum disorder.

    PubMed

    Baum, Katherine T; Shear, Paula K; Howe, Steven R; Bishop, Somer L

    2015-08-01

    In autism spectrum disorders, results of cognitive testing inform clinical care, theories of neurodevelopment, and research design. The Wechsler Intelligence Scale for Children and the Stanford-Binet are commonly used in autism spectrum disorder evaluations and scores from these tests have been shown to be highly correlated in typically developing populations. However, they have not been compared in individuals with autism spectrum disorder, whose core symptoms can make testing challenging, potentially compromising test reliability. We used a within-subjects research design to evaluate the convergent validity between the Wechsler Intelligence Scale for Children, 4th ed., and Stanford-Binet, 5th ed., in 40 youth (ages 10-16 years) with autism spectrum disorder. Corresponding intelligence scores were highly correlated (r = 0.78 to 0.88), but full-scale intelligence quotient (IQ) scores (t(38) = -2.27, p = 0.03, d = -0.16) and verbal IQ scores (t(36) = 2.23, p = 0.03; d = 0.19) differed between the two tests. Most participants obtained higher full-scale IQ scores on the Stanford-Binet, 5th ed., compared to Wechsler Intelligence Scale for Children, 4th ed., with 14% scoring more than one standard deviation higher. In contrast, verbal indices were higher on the Wechsler Intelligence Scale for Children, 4th ed., Verbal-nonverbal discrepancy classifications were only consistent for 60% of the sample. Comparisons of IQ test scores in autism spectrum disorder and other special groups are important, as it cannot necessarily be assumed that convergent validity findings in typically developing children and adolescents hold true across all pediatric populations. © The Author(s) 2014.

  7. Development profile in a patient with monosomy 10q and Dup(17p) associated with a peripheral neuropathy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pellegrino, J.E.; Spinner, N.B.; Zackai, E.H.

    1996-02-02

    We report on a patient with dup(17p) and monosomy (10q) resulting from a familial translocation. Manifestations typical of both syndromes were present. The overall development of this patient was better by comparison with similar reported cases of either anomaly. Our evaluation detected severe gross motor delay and signs of a demyelinating peripheral neuropathy. This patient is trisomic for the region of 17p which includes the peripheral myelin protein-22 (PMP-22) gene, known to be duplicated in Charcot-Marie-Tooth neuropathy type 1A (CMT1A). Our analysis in this patient suggests that trisomy for the PMP-22 gene led to the demyelinating neuropathy and contributed tomore » his severe motor development delay. 33 refs., 3 figs., 1 tab.« less

  8. Gender classification in low-resolution surveillance video: in-depth comparison of random forests and SVMs

    NASA Astrophysics Data System (ADS)

    Geelen, Christopher D.; Wijnhoven, Rob G. J.; Dubbelman, Gijs; de With, Peter H. N.

    2015-03-01

    This research considers gender classification in surveillance environments, typically involving low-resolution images and a large amount of viewpoint variations and occlusions. Gender classification is inherently difficult due to the large intra-class variation and interclass correlation. We have developed a gender classification system, which is successfully evaluated on two novel datasets, which realistically consider the above conditions, typical for surveillance. The system reaches a mean accuracy of up to 90% and approaches our human baseline of 92.6%, proving a high-quality gender classification system. We also present an in-depth discussion of the fundamental differences between SVM and RF classifiers. We conclude that balancing the degree of randomization in any classifier is required for the highest classification accuracy. For our problem, an RF-SVM hybrid classifier exploiting the combination of HSV and LBP features results in the highest classification accuracy of 89.9 0.2%, while classification computation time is negligible compared to the detection time of pedestrians.

  9. Transport of Space Environment Electrons: A Simplified Rapid-Analysis Computational Procedure

    NASA Technical Reports Server (NTRS)

    Nealy, John E.; Anderson, Brooke M.; Cucinotta, Francis A.; Wilson, John W.; Katz, Robert; Chang, C. K.

    2002-01-01

    A computational procedure for describing transport of electrons in condensed media has been formulated for application to effects and exposures from spectral distributions typical of electrons trapped in planetary magnetic fields. The procedure is based on earlier parameterizations established from numerous electron beam experiments. New parameterizations have been derived that logically extend the domain of application to low molecular weight (high hydrogen content) materials and higher energies (approximately 50 MeV). The production and transport of high energy photons (bremsstrahlung) generated in the electron transport processes have also been modeled using tabulated values of photon production cross sections. A primary purpose for developing the procedure has been to provide a means for rapidly performing numerous repetitive calculations essential for electron radiation exposure assessments for complex space structures. Several favorable comparisons have been made with previous calculations for typical space environment spectra, which have indicated that accuracy has not been substantially compromised at the expense of computational speed.

  10. Artificial intelligence in peer review: How can evolutionary computation support journal editors?

    PubMed Central

    Fronczak, Piotr; Fronczak, Agata; Ausloos, Marcel; Nedic, Olgica

    2017-01-01

    With the volume of manuscripts submitted for publication growing every year, the deficiencies of peer review (e.g. long review times) are becoming more apparent. Editorial strategies, sets of guidelines designed to speed up the process and reduce editors’ workloads, are treated as trade secrets by publishing houses and are not shared publicly. To improve the effectiveness of their strategies, editors in small publishing groups are faced with undertaking an iterative trial-and-error approach. We show that Cartesian Genetic Programming, a nature-inspired evolutionary algorithm, can dramatically improve editorial strategies. The artificially evolved strategy reduced the duration of the peer review process by 30%, without increasing the pool of reviewers (in comparison to a typical human-developed strategy). Evolutionary computation has typically been used in technological processes or biological ecosystems. Our results demonstrate that genetic programs can improve real-world social systems that are usually much harder to understand and control than physical systems. PMID:28931033

  11. Activities of daily living in children with developmental coordination disorder: dressing, personal hygiene, and eating skills.

    PubMed

    Summers, Janet; Larkin, Dawne; Dewey, Deborah

    2008-04-01

    In order to understand how age, culture, and problems in motor coordination impact the performance of activities of daily living, we used focus groups and in-depth interviews with Australian and Canadian parents to examine activities of daily living of younger (5-7 years of age) and older (8-9 years of age) children with and without DCD. By comparison with their typically developing age group, children with DCD had more difficulty with dressing, personal hygiene, and eating skills. Difficulties with postural control and fine-motor skills were reported to contribute to poorer performance of activities of daily living. As expected, competence in the performance of activities of daily living improved in the older children with and without DCD and there were few differences in the performance of daily living tasks between typical children in Australia and Canada. Overall, the motor difficulties of children with DCD had a significant impact on performance of a wide range of daily activities.

  12. Simulation of tidal flow and circulation patterns in the Loxahatchee River Estuary, southeastern Florida

    USGS Publications Warehouse

    Russell, G.M.; Goodwin, C.R.

    1987-01-01

    Results of a two-dimensional, vertically averaged, computer simulation model of the Loxahatchee River estuary show that under typical low freshwater inflow and vertically well mixed conditions, water circulation is dominated by freshwater inflow rather than by tidal influence. The model can simulate tidal flow and circulation in the Loxahatchee River estuary under typical low freshwater inflow and vertically well mixed conditions, but is limited, however, to low-flow and well mixed conditions. Computed patterns of residual water transport show a consistent seaward flow from the northwest fork through the central embayment and out Jupiter Inlet to the Atlantic Ocean. A large residual seaward flow was computed from the North Intracoastal Waterway to the inlet channel. Although the tide produces large flood and ebb flows in the estuary, tide-induced residual transport rates are low in comparison with freshwater-induced residual transport. Model investigations of partly mixed or stratified conditions in the estuary need to await development of systems capable of simulating three-dimensional flow patterns. (Author 's abstract)

  13. Ebola and Marburg Hemorrhagic Fevers: Neglected Tropical Diseases?

    PubMed Central

    MacNeil, Adam; Rollin, Pierre E.

    2012-01-01

    Ebola hemorrhagic fever (EHF) and Marburg hemorrhagic fever (MHF) are rare viral diseases, endemic to central Africa. The overall burden of EHF and MHF is small in comparison to the more common protozoan, helminth, and bacterial diseases typically referred to as neglected tropical diseases (NTDs). However, EHF and MHF outbreaks typically occur in resource-limited settings, and many aspects of these outbreaks are a direct consequence of impoverished conditions. We will discuss aspects of EHF and MHF disease, in comparison to the “classic” NTDs, and examine potential ways forward in the prevention and control of EHF and MHF in sub-Saharan Africa, as well as examine the potential for application of novel vaccines or antiviral drugs for prevention or control of EHF and MHF among populations at highest risk for disease. PMID:22761967

  14. Early androgens, activity levels and toy choices of children in the second year of life.

    PubMed

    Alexander, Gerianne M; Saenz, Janet

    2012-09-01

    The hypothesis that stronger preferences for active play styles contribute to stronger preferences for male-typical toys was examined in 47 boys and 37 girls at 19-months of age using ambulatory monitoring technology (i.e., actigraphy) to measure activity levels during contact with male-typical, female-typical, and gender-neutral toys. Digit ratios and salivary testosterone levels were measured earlier in children at 3-4 months of age. There were no significant sex differences in digit ratios, salivary testosterone levels, or overall activity levels during toy play. In contrast, contact times showed large sex differences in infants' toy preferences. The within-sex comparisons showed that infant girls had significant preferences for female-typical toys over male-typical toys, whereas infant boys showed only a small preference for male-typical toys over female-typical toys. More male-typical digit ratios in early infancy predicted higher activity counts during toy play and less female-typical toy preferences in girls. However, in both sexes, activity levels were unrelated to toy preferences suggesting that factors other than activity level preferences contribute to the early emergence of gender-linked toy preferences. Copyright © 2012 Elsevier Inc. All rights reserved.

  15. Childhood Arthritis and Rheumatology Research Alliance consensus clinical treatment plans for juvenile dermatomyositis with skin predominant disease.

    PubMed

    Kim, Susan; Kahn, Philip; Robinson, Angela B; Lang, Bianca; Shulman, Andrew; Oberle, Edward J; Schikler, Kenneth; Curran, Megan Lea; Barillas-Arias, Lilliana; Spencer, Charles H; Rider, Lisa G; Huber, Adam M

    2017-01-11

    Juvenile dermatomyositis (JDM) is the most common form of the idiopathic inflammatory myopathies in children. A subset of children have the rash of JDM without significant weakness, and the optimal treatments for these children are unknown. The goal of this study was to describe the development of consensus clinical treatment plans (CTPs) for children with JDM who have active skin rashes, without significant muscle involvement, referred to as skin predominant JDM in this manuscript. The Children's Arthritis and Rheumatology Research Alliance (CARRA) is a North American consortium of pediatric rheumatology health care providers. CARRA members collaborated to determine consensus on typical treatments for JDM patients with skin findings without significant weakness, to develop CTPs for this subgroup of patients. We used a combination of Delphi surveys and nominal group consensus meetings to develop these CTPs. Consensus was reached on patient characteristics and outcome assessment, and CTPs were developed and finalized for patients with skin predominant JDM. Treatment option A included hydroxychloroquine alone, Treatment option B included hydroxychloroquine and methotrexate, and Treatment option C included hydroxychloroquine, methotrexate and corticosteroids. Three CTPs were developed for use in children with skin predominant JDM, which reflect typical treatment approaches. These are not considered to be specific recommendations or standard of care. Using the CARRA network and prospective data collection, we will be able to apply statistical methods in the future to allow comparisons of JDM patients following these consensus treatment plans.

  16. Impaired induction of long-term potentiation-like plasticity in patients with high-functioning autism and Asperger syndrome.

    PubMed

    Jung, Nikolai H; Janzarik, Wibke G; Delvendahl, Igor; Münchau, Alexander; Biscaldi, Monica; Mainberger, Florian; Bäumer, Tobias; Rauh, Reinhold; Mall, Volker

    2013-01-01

    We aimed to investigate the induction of long-term potentiation (LTP)-like plasticity by paired associative stimulation (PAS) in patients with high-functioning autism and Asperger syndrome (HFA/AS). PAS with an interstimulus interval between electrical and transcranial magnetic stimulation of 25 ms (PAS(25)) was performed in patients with HFA/AS (n=9; eight males, one female; mean age 17 y 11 mo, SD 4 y 5 mo) and in typically developing age-matched volunteers (n=9; five males, four females; mean age 22 y 4 mo, SD 5 y 2 mo). The amplitude of motor-evoked potentials was measured before PAS(25), immediately after stimulation, and 30 minutes and 60 minutes later. A PAS protocol adapted to individual N20 latency (PAS(N20+2)) was performed in six additional patients with HFA/AS. Short-interval intracortical inhibition was measured using paired-pulse stimulation. In contrast to the typically developing participants, the patients with HFA/AS did not show a significant increase in motor-evoked potentials after PAS(25). This finding could also be demonstrated after adaptation for N20 latency. Short-interval intracortical inhibition of patients with HFA/AS was normal compared with the comparison group and did not correlate with PAS effect. Our results show a significant impairment of LTP-like plasticity induced by PAS in individuals with HFA/AS compared with typically developing participants. This finding is in accordance with results from animal studies as well as human studies. Impaired LTP-like plasticity in patients with HFA/AS points towards reduced excitatory synaptic connectivity and deficits in sensory-motor integration in these patients. © The Authors. Developmental Medicine & Child Neurology © 2012 Mac Keith Press.

  17. Coordination between pelvis and shoulder girdle during walking in bilateral cerebral palsy.

    PubMed

    Tavernese, Emanuela; Paoloni, Marco; Mangone, Massimiliano; Castelli, Enrico; Santilli, Valter

    2016-02-01

    Studies revealed that pelvis and shoulder girdle kinematics is impaired in children with the diplegic form of bilateral cerebral palsy while walking. The features of 3D coordination between these segments, however, have never been evaluated. The gait analyses of 27 children with bilateral cerebral palsy (18 males; mean age 124 months) have been retrospectively reviewed from the database of a Movement Analysis Laboratory. The spatial-temporal parameters and the range-of-motions of the pelvis and of the shoulder girdle on the three planes of motion have been calculated. Continuous relative phase has been calculated for the 3D pelvis-shoulder girdle couplings on the transverse, sagittal and frontal planes of motion to determine coordination between these segments. Data from 10 typically developed children have been used for comparison. Children with bilateral cerebral palsy walk with lower velocity (P=0.01), shorter steps (P<0.0001), larger base of support (P<0.01) and increased duration of the double support phase (P=0.005) when compared to typically developed children. The mean continuous relative phase on the transverse plane has been found lower in the cerebral palsy group throughout the gait cycle (P=0.003), as well as in terminal stance, pre-swing and mid-swing. The age, gait speed and pelvis range-of-motions on the transverse plane have been found correlated to continuous relative phase on the transverse plane. Compared with typically developed children, children with bilateral cerebral palsy show a more in-phase coordination between the pelvis and the shoulder girdle on the transverse plane while walking. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. Pump/Control System Minimum Operating Cost Testing

    NASA Technical Reports Server (NTRS)

    1977-01-01

    A preliminary evaluation of pump performance was initiated to determine the efficiencies of an arbitrary group of small pumps. Trends in factors affecting energy usage in typical prime movers which might be used in liquid transport solar systems were assessed. Comparisons of centrifugal pump efficiencies were made from one manufacturer to another. Tests were also made on two positive-displacement pumps and comparisons with centrifugal pumps were observed.

  19. Determination of ionospheric electron density profiles from satellite UV (Ultraviolet) emission measurements, fiscal year 1984

    NASA Astrophysics Data System (ADS)

    Daniell, R. E.; Strickland, D. J.; Decker, D. T.; Jasperse, J. R.; Carlson, H. C., Jr.

    1985-04-01

    The possible use of satellite ultraviolet measurements to deduce the ionospheric electron density profile (EDP) on a global basis is discussed. During 1984 comparisons were continued between the hybrid daytime ionospheric model and the experimental observations. These comparison studies indicate that: (1) the essential features of the EDP and certain UV emissions can be modelled; (2) the models are sufficiently sensitive to input parameters to yield poor agreement with observations when typical input values are used; (3) reasonable adjustments of the parameters can produce excellent agreement between theory and data for either EDP or airglow but not both; and (4) the qualitative understanding of the relationship between two input parameters (solar flux and neutral densities) and the model EDP and airglow features has been verified. The development of a hybrid dynamic model for the nighttime midlatitude ionosphere has been initiated. This model is similar to the daytime hybrid model, but uses the sunset EDP as an initial value and calculates the EDP as a function of time through the night. In addition, a semiempirical model has been developed, based on the assumption that the nighttime EDP is always well described by a modified Chapman function. This model has great simplicity and allows the EDP to be inferred in a straightforward manner from optical observations. Comparisons with data are difficult, however, because of the low intensity of the nightglow.

  20. A price and use comparison of generic versus originator cardiovascular medicines: a hospital study in Chongqing, China

    PubMed Central

    2013-01-01

    Background Developed countries use generic competition to contain pharmaceutical expenditure. China, as a developing and transitional country, has not yet deemed an increase in the use of generic products as important; otherwise, much effort has been made to decrease the drug prices. This paper aims to explore dynamically the price and use comparison of generic and originator drugs in China, and estimate the potential savings of patients from switching originator drugs to generics. Methods A typical hospital in Chongqing, China, was selected to examine the price and use comparisons of 12 cardiovascular drugs from 2006 to 2011. Results The market share of the 12 generic medicines studied in this paper was 34.37% for volume and 31.33% for value in the second half of 2011. The price ratio of generic to originator drugs was between 0.34 and 0.98, and the volume price index of originators to generics was 1.63. The potential savings of patients from switching originator drugs to generics is 65%. Conclusion The market share of the generics was lowering and the weighted mean price kept increasing in face of the strict price control. Under the background of hospitals both prescribing and dispensing medicines, China’s comprehensive healthcare policy makers should take measures from supply and demand sides to promote the consumption of generic medicines. PMID:24093493

  1. Narrative abilities, memory and attention in children with a specific language impairment.

    PubMed

    Duinmeijer, Iris; de Jong, Jan; Scheper, Annette

    2012-01-01

    While narrative tasks have proven to be valid measures for detecting language disorders, measuring communicative skills and predicting future academic performance, research into the comparability of different narrative tasks has shown that outcomes are dependent on the type of task used. Although many of the studies detecting task differences touch upon the fact that tasks place differential demands on cognitive abilities like auditory attention and memory, few studies have related specific narrative tasks to these cognitive abilities. Examining this relation is especially warranted for children with specific language impairment (SLI), who are characterized by language problems, but often have problems in other cognitive domains as well. In the current research, a comparison was made between a story retelling task (The Bus Story) and a story generation task (The Frog Story) in a group of children with SLI (n= 34) and a typically developing group (n= 38) from the same age range. In addition to the two narrative tasks, sustained auditory attention (TEA-Ch) and verbal working memory (WISC digit span and the Dutch version of the CVLT-C word list recall) were measured. Correlations were computed between the narrative, the memory and the attention scores. A group comparison showed that the children with SLI scored significantly worse than the typically developing children on several narrative measures as well as on sustained auditory attention and verbal working memory. A within-subjects comparison of the scores on the two narrative tasks showed a contrast between the tasks on several narrative measures. Furthermore, correlational analyses showed that, on the level of plot structure, the story generation task correlated with sustained auditory attention, while the story retelling task correlated with word list recall. Mean length of utterance (MLU) on the other hand correlated with digit span but not with sustained auditory attention. While children with SLI have problems with narratives in general, their performance is also dependent on the specific elicitation task used for research or diagnostics. Various narrative tasks generate different scores and are differentially correlated to cognitive skills like attention and memory, making the selection of a given task crucial in the clinical setting. © 2012 Royal College of Speech and Language Therapists.

  2. Expansion of transient operating data

    NASA Astrophysics Data System (ADS)

    Chipman, Christopher; Avitabile, Peter

    2012-08-01

    Real time operating data is very important to understand actual system response. Unfortunately, the amount of physical data points typically collected is very small and often interpretation of the data is difficult. Expansion techniques have been developed using traditional experimental modal data to augment this limited set of data. This expansion process allows for a much improved description of the real time operating response. This paper presents the results from several different structures to show the robustness of the technique. Comparisons are made to a more complete set of measured data to validate the approach. Both analytical simulations and actual experimental data are used to illustrate the usefulness of the technique.

  3. Treatment efficacy of intramuscular promethazine for Space Motion Sickness

    NASA Technical Reports Server (NTRS)

    Davis, Jeffrey R.; Jennings, Richard T.; Beck, Bradley G.; Bagian, James P.

    1993-01-01

    Intramuscular promethazine and its efficacy in the treatment of Space Motion Sickness (SMS) were evaluated using standardized questions administered during postflight debriefings to crewmembers immediately after their first Shuttle flight. The comparison showed that 25 percent of crewmembers treated with IM promethazine were 'sick' on flight day 2, compared to 50 percent of crewmembers who did not receive promethazine, 90 percent reported immediate symptom relief as well. Untreated crewmembers typically have slow symptom resolution over 72-96 h, and those treated with oral scopolamine/dextroamphetamine show delayed symptom development. This study suggests that intramuscular promethazine is an effective treatment for SMS and merits continued use and further controlled investigations.

  4. Ceramic and polymeric solid electrolytes for lithium-ion batteries

    NASA Astrophysics Data System (ADS)

    Fergus, Jeffrey W.

    Lithium-ion batteries are important for energy storage in a wide variety of applications including consumer electronics, transportation and large-scale energy production. The performance of lithium-ion batteries depends on the materials used. One critical component is the electrolyte, which is the focus of this paper. In particular, inorganic ceramic and organic polymer solid-electrolyte materials are reviewed. Solid electrolytes provide advantages in terms of simplicity of design and operational safety, but typically have conductivities that are lower than those of organic liquid electrolytes. This paper provides a comparison of the conductivities of solid-electrolyte materials being used or developed for use in lithium-ion batteries.

  5. Uniform color space analysis of LACIE image products

    NASA Technical Reports Server (NTRS)

    Nalepka, R. F. (Principal Investigator); Balon, R. J.; Cicone, R. C.

    1979-01-01

    The author has identified the following significant results. Analysis and comparison of image products generated by different algorithms show that the scaling and biasing of data channels for control of PFC primaries lead to loss of information (in a probability-of misclassification sense) by two major processes. In order of importance they are: neglecting the input of one channel of data in any one image, and failing to provide sufficient color resolution of the data. The scaling and biasing approach tends to distort distance relationships in data space and provides less than desirable resolution when the data variation is typical of a developed, nonhazy agricultural scene.

  6. Cultural Differences in Donation Decision-Making.

    PubMed

    Wang, Yan; Tang, Yi-Yuan; Wang, Jinjun

    2015-01-01

    Decisions to help those in need are essential for human development and survival. Previous studies have demonstrated the "identified effect", in which one identifiable individual typically invokes stronger feelings of compassion and receives greater aid than statistical victim. However, this preference might be influenced by cultural differences. In the current study, Chinese respondents' ratings of distress and sympathy and their willingness to contribute are greater for a group of sick children than an individual. In the U.S., greater willingness to help and sympathy are elicited by an identified victim in comparison with an unidentified one. The different results may demonstrate the importance of cultural differences when trying to understand people's prosocial behavior.

  7. Numerical modeling of pollutant transport using a Lagrangian marker particle technique

    NASA Technical Reports Server (NTRS)

    Spaulding, M.

    1976-01-01

    A derivation and code were developed for the three-dimensional mass transport equation, using a particle-in-cell solution technique, to solve coastal zone waste discharge problems where particles are a major component of the waste. Improvements in the particle movement techniques are suggested and typical examples illustrated. Preliminary model comparisons with analytic solutions for an instantaneous point release in a uniform flow show good results in resolving the waste motion. The findings to date indicate that this computational model will provide a useful technique to study the motion of sediment, dredged spoils, and other particulate waste commonly deposited in coastal waters.

  8. Reaction Time Variability in Children With ADHD Symptoms and/or Dyslexia

    PubMed Central

    Gooch, Debbie; Snowling, Margaret J.; Hulme, Charles

    2012-01-01

    Reaction time (RT) variability on a Stop Signal task was examined among children with attention deficit hyperactivity disorder (ADHD) symptoms and/or dyslexia in comparison to typically developing (TD) controls. Children's go-trial RTs were analyzed using a novel ex-Gaussian method. Children with ADHD symptoms had increased variability in the fast but not the slow portions of their RT distributions compared to those without ADHD symptoms. The RT distributions of children with dyslexia were similar to those of TD-controls. It is argued that variability in responding may be underpinned by impairments in response preparation or timing during Stop Signal tasks. PMID:22799763

  9. Referential communication in children with autism spectrum disorder.

    PubMed

    Dahlgren, Svenolof; Sandberg, Annika Dahlgren

    2008-07-01

    Referential communication was studied in children with autism spectrum disorder (ASD) including children with autism and Asperger syndrome. The aim was to study alternative explanations for the children's communicative problems in such situations. Factors studied were theory of mind, IQ, verbal ability and memory. The main results demonstrated diminished performance in children with autism spectrum disorder, mirroring performance in everyday life, in comparison to verbal IQ and mental age matched typically developing children. Among children with autism spectrum disorders, there was a positive relationship between performance in referential communication and theory of mind. Memory capacity also proved to play a role in success in the task.

  10. Benchmarking of Advanced Control Strategies for a Simulated Hydroelectric System

    NASA Astrophysics Data System (ADS)

    Finotti, S.; Simani, S.; Alvisi, S.; Venturini, M.

    2017-01-01

    This paper analyses and develops the design of advanced control strategies for a typical hydroelectric plant during unsteady conditions, performed in the Matlab and Simulink environments. The hydraulic system consists of a high water head and a long penstock with upstream and downstream surge tanks, and is equipped with a Francis turbine. The nonlinear characteristics of hydraulic turbine and the inelastic water hammer effects were considered to calculate and simulate the hydraulic transients. With reference to the control solutions addressed in this work, the proposed methodologies rely on data-driven and model-based approaches applied to the system under monitoring. Extensive simulations and comparisons serve to determine the best solution for the development of the most effective, robust and reliable control tool when applied to the considered hydraulic system.

  11. Vocal patterns in infants with autism spectrum disorder: canonical babbling status and vocalization frequency.

    PubMed

    Patten, Elena; Belardi, Katie; Baranek, Grace T; Watson, Linda R; Labban, Jeffrey D; Oller, D Kimbrough

    2014-10-01

    Canonical babbling is a critical milestone for speech development and is usually well in place by 10 months. The possibility that infants with autism spectrum disorder (ASD) show late onset of canonical babbling has so far eluded evaluation. Rate of vocalization or "volubility" has also been suggested as possibly aberrant in infants with ASD. We conducted a retrospective video study examining vocalizations of 37 infants at 9-12 and 15-18 months. Twenty-three of the 37 infants were later diagnosed with ASD and indeed produced low rates of canonical babbling and low volubility by comparison with the 14 typically developing infants. The study thus supports suggestions that very early vocal patterns may prove to be a useful component of early screening and diagnosis of ASD.

  12. Vocal patterns in infants with Autism Spectrum Disorder: Canonical babbling status and vocalization frequency

    PubMed Central

    Patten, Elena; Belardi, Katie; Baranek, Grace T.; Watson, Linda R.; Labban, Jeffrey D.; Oller, D. Kimbrough

    2014-01-01

    Canonical babbling is a critical milestone for speech development and is usually well in place by 10 months. The possibility that infants with ASD show late onset of canonical babbling has so far eluded evaluation. Rate of vocalization or “volubility” has also been suggested as possibly aberrant in infants with ASD. We conducted a retrospective video study examining vocalizations of 37 infants at 9–12 and 15–18 months. Twenty-three of the 37 infants were later diagnosed with ASD and indeed produced low rates of canonical babbling and low volubility by comparison with the 14 typically developing infants. The study thus supports suggestions that very early vocal patterns may prove to be a useful component of early screening and diagnosis of ASD. PMID:24482292

  13. Development and regulation of single- and multi-species Candida albicans biofilms

    PubMed Central

    Lohse, Matthew B.; Gulati, Megha; Johnson, Alexander D.; Nobile, Clarissa J.

    2017-01-01

    Candida albicans is among the most prevalent fungal species of the human microbiota and asymptomatically colonizes healthy individuals. However, it is also an opportunistic pathogen that can cause severe, and often fatal, bloodstream infections. The medical impact of C. albicans typically depends on its ability to form biofilms, which are closely packed communities of cells that attach to surfaces, such as tissues and implanted medical devices. In this Review, we provide an overview of the processes involved in the formation of C. albicans biofilms and discuss the core transcriptional network that regulates biofilm development. We also consider some of the advantages that biofilms provide to C. albicans in comparison with planktonic growth and explore polymicrobial biofilms that are formed by C. albicans and certain bacterial species. PMID:29062072

  14. Measured effects of surface cloth impressions on polar backscatter and comparison with a reflection grating model

    NASA Technical Reports Server (NTRS)

    Madaras, Eric I.; Brush, Edwin F., III; Bridal, S. L.; Holland, Mark R.; Miller, James G.

    1992-01-01

    This paper focuses on the nature of a typical composite surface and its effects on scattering. Utilizing epoxy typical of that in composites and standard composite fabrication methods, a sample with release cloth impressions on its surface is produced. A simple model for the scattering from the surface impressions of this sample is constructed and then polar backscatter measurements are made on the sample and compared with the model predictions.

  15. Changing epistemologies under conditions of social change in two Arab communities in Israel.

    PubMed

    Weinstock, Michael

    2015-02-01

    The study of epistemic thinking focuses on how people understand and coordinate objective and subjective aspects of knowing and make sense of multiple and discrepant knowledge claims. Typically described in terms of normative development, cross-cultural studies show differences in epistemic development and characteristics of epistemic thinking. This study focuses on within-culture variations of epistemic thinking, with the assumption that social change will produce changes in development. Arab society in Israel has undergone notable change over the last half century. In this cross-sectional research design, cross-generational comparison and rural-urban comparison were used as proxies for longitudinal social change. Three generations of Muslim Arab women in a village in Israel (20 adolescents, 20 mothers and 20 grandmothers) and 20 Muslim Arab adolescents from a large, mixed city in the same region responded to six dilemmas invoking epistemic thinking. Village adolescents were more subjectivist than their mothers and grandmothers. Sociodemographic characteristics representing greater exposure to diverse people and ideas accounted for generational differences. Both urban and rural adolescents tended towards subjectivist perspectives, and they did not differ. Parents' education levels emerged as the sociodemographic variables most consistently related to epistemic thinking. Epistemic thinking mediated the relationship between generation and gender role/cross-sex relation values. © 2014 International Union of Psychological Science.

  16. Severe community-acquired Enterobacter pneumonia: a plea for greater awareness of the concept of health-care-associated pneumonia

    PubMed Central

    2011-01-01

    Background Patients with Enterobacter community-acquired pneumonia (EnCAP) were admitted to our intensive care unit (ICU). Our primary aim was to describe them as few data are available on EnCAP. A comparison with CAP due to common and typical bacteria was performed. Methods Baseline clinical, biological and radiographic characteristics, criteria for health-care-associated pneumonia (HCAP) were compared between each case of EnCAP and thirty age-matched typical CAP cases. A univariate and multivariate logistic regression analysis was performed to determine factors independently associated with ENCAP. Their outcome was also compared. Results In comparison with CAP due to common bacteria, a lower leukocytosis and constant HCAP criteria were associated with EnCAP. Empiric antibiotic therapy was less effective in EnCAP (20%) than in typical CAP (97%) (p < 0.01). A delay in the initiation of appropriate antibiotic therapy (3.3 ± 1.6 vs. 1.2 ± 0.6 days; p < 0.01) and an increase in duration of mechanical ventilation (8.4 ± 5.2 vs. 4.0 ± 4.3 days; p = 0.01) and ICU stay were observed in EnCAP patients. Conclusions EnCAP is a severe infection which is more consistent with HCAP than with typical CAP. This retrospectively suggests that the application of HCAP guidelines should have improved EnCAP management. PMID:21569334

  17. Creativity and Entrepreneurship: How Do They Relate?

    ERIC Educational Resources Information Center

    Whiting, Bruce G.

    1988-01-01

    Research reports are reviewed which illustrate the close ties between creativity and entrepreneurship. Comparisons of the characteristics and behavior typical of creative individuals and entrepreneurial individuals indicate the existence of striking similarities. (JDD)

  18. Genomics, evolution and development of amphioxus and tunicates: The Goldilocks principle.

    PubMed

    Holland, Linda Z

    2015-06-01

    Morphological comparisons among extant animals have long been used to infer their long-extinct ancestors for which the fossil record is poor or non-existent. For evolution of the vertebrates, the comparison has typically involved amphioxus and vertebrates. Both groups are evolving relatively slowly, and their genomes share a high level of synteny. Both vertebrates and amphioxus have regulative development in which cell fates become fixed only gradually during embryogenesis. Thus, their development fits a modified hourglass model in which constraints are greatest at the phylotypic stage (i.e., the late neurula/early larva), but are somewhat greater on earlier development than on later development. In contrast, the third group of chordates, the tunicates, which are sister group to vertebrates, are evolving rapidly. Constraints on evolution of tunicate genomes are relaxed, and they have discarded key developmental genes and organized much of their coding sequences into operons, which are transcribed as a single mRNA that undergoes trans-splicing. This contrasts with vertebrates and amphioxus, whose genomes are not organized into operons. Concomitantly, tunicates have switched to determinant development with very early fixation of cell fates. Thus, tunicate development more closely fits a progressive divergence model (shaped more like a wine glass than an hourglass) in which the constraints on the zygote and very early development are greatest. This model can help explain why tunicate body plans are so very diverse. The relaxed constraints on development after early cleavage stages are correlated with relaxed constraints on genome evolution. The question remains: which came first? © 2014 Wiley Periodicals, Inc.

  19. The cognitive foundations of early arithmetic skills: It is counting and number judgment, but not finger gnosis, that count.

    PubMed

    Long, Imogen; Malone, Stephanie A; Tolan, Anne; Burgoyne, Kelly; Heron-Delaney, Michelle; Witteveen, Kate; Hulme, Charles

    2016-12-01

    Following on from ideas developed by Gerstmann, a body of work has suggested that impairments in finger gnosis may be causally related to children's difficulties in learning arithmetic. We report a study with a large sample of typically developing children (N=197) in which we assessed finger gnosis and arithmetic along with a range of other relevant cognitive predictors of arithmetic skills (vocabulary, counting, and symbolic and nonsymbolic magnitude judgments). Contrary to some earlier claims, we found no meaningful association between finger gnosis and arithmetic skills. Counting and symbolic magnitude comparison were, however, powerful predictors of arithmetic skills, replicating a number of earlier findings. Our findings seriously question theories that posit either a simple association or a causal connection between finger gnosis and the development of arithmetic skills. Crown Copyright © 2016. Published by Elsevier Inc. All rights reserved.

  20. Semantic Verbal Fluency in Children with and without Autism Spectrum Disorder: Relationship with Chronological Age and IQ

    PubMed Central

    Pastor-Cerezuela, Gemma; Fernández-Andrés, Maria-Inmaculada; Feo-Álvarez, Mireia; González-Sala, Francisco

    2016-01-01

    We administered a semantic verbal fluency (SVF) task to two groups of children (age range from 5 to 8): 47 diagnosed with Autism Spectrum Disorder (ASD Group) and 53 with typical development (Comparison Group), matched on gender, chronological age, and non-verbal IQ. Four specific indexes were calculated from the SVF task, reflecting the different underlying cognitive strategies used: clustering (component of generativity and lexical-semantic access), and switching (executive component, cognitive flexibility). First, we compared the performance of the two groups on the different SVF task indicators, with the ASD group scoring lower than the Comparison Group, although the difference was greater on switching than on clustering. Second, we analyzed the relationships between the different SVF measures and chronological age, verbal IQ and non-verbal IQ. While in the Comparison Group chronological age was the main predictor of performance on the SVF task, in the ASD Group verbal IQ was the best predictor. In the children with ASD, therefore, greater linguistic competence would be associated with better performance on the SVF task, which should be taken into account in speech therapies designed to achieve improvements in linguistic generativity and cognitive flexibility. PMID:27379002

  1. Comparison of Two Multidisciplinary Optimization Strategies for Launch-Vehicle Design

    NASA Technical Reports Server (NTRS)

    Braun, R. D.; Powell, R. W.; Lepsch, R. A.; Stanley, D. O.; Kroo, I. M.

    1995-01-01

    The investigation focuses on development of a rapid multidisciplinary analysis and optimization capability for launch-vehicle design. Two multidisciplinary optimization strategies in which the analyses are integrated in different manners are implemented and evaluated for solution of a single-stage-to-orbit launch-vehicle design problem. Weights and sizing, propulsion, and trajectory issues are directly addressed in each optimization process. Additionally, the need to maintain a consistent vehicle model across the disciplines is discussed. Both solution strategies were shown to obtain similar solutions from two different starting points. These solutions suggests that a dual-fuel, single-stage-to-orbit vehicle with a dry weight of approximately 1.927 x 10(exp 5)lb, gross liftoff weight of 2.165 x 10(exp 6)lb, and length of 181 ft is attainable. A comparison of the two approaches demonstrates that treatment or disciplinary coupling has a direct effect on optimization convergence and the required computational effort. In comparison with the first solution strategy, which is of the general form typically used within the launch vehicle design community at present, the second optimization approach is shown to he 3-4 times more computationally efficient.

  2. Calibration of the DRASTIC ground water vulnerability mapping method

    USGS Publications Warehouse

    Rupert, M.G.

    2001-01-01

    Ground water vulnerability maps developed using the DRASTIC method have been produced in many parts of the world. Comparisons of those maps with actual ground water quality data have shown that the DRASTIC method is typically a poor predictor of ground water contamination. This study significantly improved the effectiveness of a modified DRASTIC ground water vulnerability map by calibrating the point rating schemes to actual ground water quality data by using nonparametric statistical techniques and a geographic information system. Calibration was performed by comparing data on nitrite plus nitrate as nitrogen (NO2 + NO3-N) concentrations in ground water to land-use, soils, and depth to first-encountered ground water data. These comparisons showed clear statistical differences between NO2 + NO3-N concentrations and the various categories. Ground water probability point ratings for NO2 + NO3-N contamination were developed from the results of these comparisons, and a probability map was produced. This ground water probability map was then correlated with an independent set of NO2 + NO3-N data to demonstrate its effectiveness in predicting elevated NO2 + NO3-N concentrations in ground water. This correlation demonstrated that the probability map was effective, but a vulnerability map produced with the uncalibrated DRASTIC method in the same area and using the same data layers was not effective. Considerable time and expense have been outlaid to develop ground water vulnerability maps with the DRASTIC method. This study demonstrates a cost-effective method to improve and verify the effectiveness of ground water vulnerability maps.

  3. Matched Comparison Group Design Standards in Systematic Reviews of Early Childhood Interventions.

    PubMed

    Thomas, Jaime; Avellar, Sarah A; Deke, John; Gleason, Philip

    2017-06-01

    Systematic reviews assess the quality of research on program effectiveness to help decision makers faced with many intervention options. Study quality standards specify criteria that studies must meet, including accounting for baseline differences between intervention and comparison groups. We explore two issues related to systematic review standards: covariate choice and choice of estimation method. To help systematic reviews develop/refine quality standards and support researchers in using nonexperimental designs to estimate program effects, we address two questions: (1) How well do variables that systematic reviews typically require studies to account for explain variation in key child and family outcomes? (2) What methods should studies use to account for preexisting differences between intervention and comparison groups? We examined correlations between baseline characteristics and key outcomes using Early Childhood Longitudinal Study-Birth Cohort data to address Question 1. For Question 2, we used simulations to compare two methods-matching and regression adjustment-to account for preexisting differences between intervention and comparison groups. A broad range of potential baseline variables explained relatively little of the variation in child and family outcomes. This suggests the potential for bias even after accounting for these variables, highlighting the need for systematic reviews to provide appropriate cautions about interpreting the results of moderately rated, nonexperimental studies. Our simulations showed that regression adjustment can yield unbiased estimates if all relevant covariates are used, even when the model is misspecified, and preexisting differences between the intervention and the comparison groups exist.

  4. Childhood Arthritis and Rheumatology Research Alliance Consensus Clinical Treatment Plans for Juvenile Dermatomyositis with Persistent Skin Rash.

    PubMed

    Huber, Adam M; Kim, Susan; Reed, Ann M; Carrasco, Ruy; Feldman, Brian M; Hong, Sandy D; Kahn, Philip; Rahimi, Homaira; Robinson, Angela Byun; Vehe, Richard K; Weiss, Jennifer E; Spencer, Charles

    2017-01-01

    Juvenile dermatomyositis (JDM) is the most common form of idiopathic inflammatory myopathy in children. While outcomes are generally thought to be good, persistence of skin rash is a common problem. The goal of this study was to describe the development of clinical treatment plans (CTP) for children with JDM characterized by persistent skin rash despite complete resolution of muscle involvement. The Childhood Arthritis and Rheumatology Research Alliance, a North American consortium of pediatric rheumatologists and other healthcare providers, used a combination of Delphi surveys and nominal group consensus meetings to develop CTP that reflected consensus on typical treatments for patients with JDM with persistent skin rash. Consensus was reached on patient characteristics and outcome assessment. Patients should have previously received corticosteroids and methotrexate (MTX). Three consensus treatment plans were developed. Plan A added intravenous immunoglobulin (IVIG) if it was not already being used. Plan B added mycophenolate mofetil, while Plan C added cyclosporine. Continuation of previous treatments, including corticosteroids, MTX, and IVIG, was permitted in plans B and C. Three consensus CTP were developed for use in children with JDM and persistent skin rash despite complete resolution of muscle disease. These CTP reflect typical treatment approaches and are not to be considered treatment recommendations or standard of care. Using prospective data collection and statistical methods to account for nonrandom treatment assignment, it is expected that these CTP will be used to allow treatment comparisons, and ultimately determine the best treatment for these patients.

  5. A method for performance comparison of polycentric knees and its application to the design of a knee for developing countries.

    PubMed

    Anand, T S; Sujatha, S

    2017-08-01

    Polycentric knees for transfemoral prostheses have a variety of geometries, but a survey of literature shows that there are few ways of comparing their performance. Our objective was to present a method for performance comparison of polycentric knee geometries and design a new geometry. In this work, we define parameters to compare various commercially available prosthetic knees in terms of their stability, toe clearance, maximum flexion, and so on and optimize the parameters to obtain a new knee design. We use the defined parameters and optimization to design a new knee geometry that provides the greater stability and toe clearance necessary to navigate uneven terrain which is typically encountered in developing countries. Several commercial knees were compared based on the defined parameters to determine their suitability for uneven terrain. A new knee was designed based on optimization of these parameters. Preliminary user testing indicates that the new knee is very stable and easy to use. The methodology can be used for better knee selection and design of more customized knee geometries. Clinical relevance The method provides a tool to aid in the selection and design of polycentric knees for transfemoral prostheses.

  6. Stakeholder-Driven Quality Improvement: A Compelling Force for Clinical Practice Guidelines.

    PubMed

    Rosenfeld, Richard M; Wyer, Peter C

    2018-01-01

    Clinical practice guideline development should be driven by rigorous methodology, but what is less clear is where quality improvement enters the process: should it be a priority-guiding force, or should it enter only after recommendations are formulated? We argue for a stakeholder-driven approach to guideline development, with an overriding goal of quality improvement based on stakeholder perceptions of needs, uncertainties, and knowledge gaps. In contrast, the widely used topic-driven approach, which often makes recommendations based only on randomized controlled trials, is driven by epidemiologic purity and evidence rigor, with quality improvement a downstream consideration. The advantages of a stakeholder-driven versus a topic-driven approach are highlighted by comparisons of guidelines for otitis media with effusion, thyroid nodules, sepsis, and acute bacterial rhinosinusitis. These comparisons show that stakeholder-driven guidelines are more likely to address the quality improvement needs and pressing concerns of clinicians and patients, including understudied populations and patients with multiple chronic conditions. Conversely, a topic-driven approach often addresses "typical" patients, based on research that may not reflect the needs of high-risk groups excluded from studies because of ethical issues or a desire for purity of research design.

  7. Measurement and Comparison of Mechanical Properties of Nitinol Stents

    NASA Astrophysics Data System (ADS)

    Hanus, Josef; Zahora, Jiri

    2005-01-01

    The self expandable Nitinol stents or stentgrafts are typically used for miniinvasive treatment of stenosis and aneurysms in the cardiovascular system. The minimal traumatisation of the patient, shorter time of hospitalization are typical advantages of these methods. More than ten years of experience has yielded also important information about the performance of stents in interaction with biological system and the possible problems related with it. The leakage or the shift of stent are some typical disadvantages, that can be related among other in the construction of the stent. The problem is that the mechanical properties, dimensions and the dynamical properties of the stent do not exactly correspond to the properties of the vessel or generally of tissue where this stent is introduced. The measurement, the description and the comparison of the relations between the mechanical properties of stents and tissues can be one of the possible ways to minimize these disadvantages. The developed original computer controlled measuring system allows the measurement of mechanical properties of stents, the measurement of strain-stress curves or simulation of interaction of the stent and vessel for exactly defined hemodynamic conditions. We measured and compared the mechanical parameters of different selfexpandable Nitinol stents, which differed in geometry (radius and length), in the type of construction (number of branches and rising of winding) and in the diameter of used wire. The results of measurements confirmed the theoretical assumptions that just the diameter of the Nitinol wire significantly influences the rigidity and the level of compressibility of the stent as well. A compromise must be found between the required rigidity of the stent and the minimal size of the delivery system. The exact description of the relation between the mechanical properties and geometry and construction of the stents enables to design the stent to fit the patient and it is expected that this access improves the efficiency of treatment. The results of measurement are also necessary for the design and identification of the parameters of the models of the stents.

  8. Is strength of handedness reliable over repeated testing? An examination of typical development and autism spectrum disorder

    PubMed Central

    Scharoun, Sara M.; Bryden, Pamela J.

    2015-01-01

    Despite a lack of agreement concerning the age at which adult-like patterns of handedness emerge, it is generally understood that hand preference presents early in life and development is variable. Young children (ages 3–5 years) are described as having weak hand preference; however, older children (ages 7–10 years) display stronger patterns. Here, strength of hand preference refers to reliable use of the preferred hand. In comparison to their typically developing (TD) peers, individuals with autism spectrum disorder (ASD) are described as having a weak hand preference. This study aimed to extend the literature to assess three measures of handedness (Waterloo Handedness Questionnaire – WHQ, Annett pegboard – AP, and WatHand Cabinet Test – WHCT) in two repeated sessions. The first research question aimed to delineate if the strength of hand use changes across testing sessions as a function of age in typical development. Right-handed children reported a reliable preference for the right hand on the WHQ, similar to adults. A marginally significant difference was revealed between 3- to 4- and 5- to 6-year-olds on the AP. This was attributed to weak lateralization in 3- to 4-year-olds, where the establishment of hand preference by age 6 leads to superior performance with the preferred hand in 5- to 6-year-olds. Finally, for the WHCT, 3- to 4-year-olds had the highest bimanual score, indicating use of the same hand to lift the cabinet door and retrieve an object. It is likely that the task was not motorically complex enough to drive preferred hand selection for older participants. The second research question sought to determine if there is difference between (TD) children and children with ASD. No differences were revealed; however, children with ASD did display variable AP performance, providing partial support for previous literature. Findings will be discussed in light of relevant literature. PMID:25691875

  9. A comparison of food refusal related to characteristics of food in children with autism spectrum disorder and typically developing children.

    PubMed

    Hubbard, Kristie L; Anderson, Sarah E; Curtin, Carol; Must, Aviva; Bandini, Linda G

    2014-12-01

    Parents of children with autism spectrum disorder (ASD) frequently report child food refusal based on characteristics of food. Our study sought to determine whether parent report of food refusal based on the characteristics of food was greater in children with ASD than in typically developing children, associated with a greater percentage of foods refused of those offered, and associated with fruit and vegetable intake. A modified food frequency questionnaire was used to determine overall food refusal as well as fruit and vegetable intake. Parent-reported food refusal related to characteristics of food (eg, texture/consistency, temperature, brand, color, shape, taste/smell, foods mixed together, or foods touching other foods) was compared between 53 children with ASD and 58 typically developing children aged 3 to 11 years in the Children's Activity and Meal Patterns Study (2007-2008). Children with ASD were significantly more likely to refuse foods based on texture/consistency (77.4% vs 36.2%), taste/smell (49.1% vs 5.2%), mixtures (45.3% vs 25.9%), brand (15.1% vs 1.7%), and shape (11.3% vs 1.7%). No differences between groups were found for food refusal based on temperature, foods touching other foods, or color. Irrespective of ASD status, the percentage of foods refused of those offered was associated with parent reports of food refusal based on all characteristics examined, except temperature. Food refusal based on color was inversely associated with vegetable consumption in both groups. Routine screening for food refusal among children with ASD is warranted to prevent dietary inadequacies that may be associated with selective eating habits. Future research is needed to develop effective and practical feeding approaches for children with ASD. Copyright © 2014 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  10. Development and validation of an improved mechanical thorax for simulating cardiopulmonary resuscitation with adjustable chest stiffness and simulated blood flow.

    PubMed

    Eichhorn, Stefan; Spindler, Johannes; Polski, Marcin; Mendoza, Alejandro; Schreiber, Ulrich; Heller, Michael; Deutsch, Marcus Andre; Braun, Christian; Lange, Rüdiger; Krane, Markus

    2017-05-01

    Investigations of compressive frequency, duty cycle, or waveform during CPR are typically rooted in animal research or computer simulations. Our goal was to generate a mechanical model incorporating alternate stiffness settings and an integrated blood flow system, enabling defined, reproducible comparisons of CPR efficacy. Based on thoracic stiffness data measured in human cadavers, such a model was constructed using valve-controlled pneumatic pistons and an artificial heart. This model offers two realistic levels of chest elasticity, with a blood flow apparatus that reflects compressive depth and waveform changes. We conducted CPR at opposing levels of physiologic stiffness, using a LUCAS device, a motor-driven plunger, and a group of volunteers. In high-stiffness mode, blood flow generated by volunteers was significantly less after just 2min of CPR, whereas flow generated by LUCAS device was superior by comparison. Optimal blood flow was obtained via motor-driven plunger, with trapezoidal waveform. Copyright © 2017 IPEM. Published by Elsevier Ltd. All rights reserved.

  11. Comparison of Children With and Without ADHD on a New Pictorial Self-Assessment of Executive Functions.

    PubMed

    Bar-Ilan, Ruthie Traub; Cohen, Noa; Maeir, Adina

    We examined the Pictorial Interview of Children's Metacognition and Executive Functions' (PIC-ME's) reliability and validity, targeting children's appraisal of their executive function (EF) in daily life. One hundred children with attention deficit hyperactivity disorder (ADHD) and 44 typically developing children (ages 5-10 yr) completed the PIC-ME. Parents completed the PIC-ME and Behavior Rating Inventory of Executive Function (BRIEF). Cronbach's α for the child PIC-ME was .914. A high correlation was found between the parent PIC-ME total and the BRIEF (r = .724). Comparisons between groups revealed significant differences on the parent PIC-ME (p < .0001) but none on the child PIC-ME. Children with ADHD identified a median of eight EF challenges they wanted to set as treatment goals. Results support the PIC-ME's initial reliability and validity among children with ADHD. Children were able to identify several EF challenges and engage in goal setting. Copyright © 2018 by the American Occupational Therapy Association, Inc.

  12. Understanding of emotions based on counterfactual reasoning in children with autism spectrum disorders.

    PubMed

    Begeer, Sander; De Rosnay, Marc; Lunenburg, Patty; Stegge, Hedy; Terwogt, Mark Meerum

    2014-04-01

    The understanding of emotions based on counterfactual reasoning was studied in children with high-functioning autism spectrum disorders (n = 71) and in typically developing children (n = 71), aged 6-12 years. Children were presented with eight stories about two protagonists who experienced the same positive or negative outcome, either due to their own action or by default. Relative to the comparison group, children with high-functioning autism spectrum disorder were poor at explaining emotions based on downward counterfactual reasoning (i.e. contentment and relief). There were no group differences in upward counterfactual reasoning (i.e. disappointment and regret). In the comparison group, second-order false-belief reasoning was related to children's understanding of second-order counterfactual emotions (i.e. regret and relief), while children in the high-functioning autism spectrum disorder group relied more on their general intellectual skills. Results are discussed in terms of the different functions of counterfactual reasoning about emotion and the cognitive style of children with high-functioning autism spectrum disorder.

  13. Mass comparisons of electric propulsion systems for NSSK of geosynchronous spacecraft. [North-South Station Keeping

    NASA Technical Reports Server (NTRS)

    Rawlin, V. K.; Majcher, G. A.

    1991-01-01

    A model was developed and exercised to allow wet mass comparisons of three-axis stabilized communications satellites delivered to geosynchronous transfer orbit. The mass benefits of using advanced chemical propulsion for apogee injection and north-south stationkeeping (NSSK) functions or electric propulsion (hydrazine arcjets and xenon ion thrusters) for NSSK functions are documented. A large derated ion thruster is proposed which minimizes thruster lifetime concerns and qualification test times when compared to those of smaller ion thrusters planned for NSSK applications. The mass benefits, which depend on the spacecraft mass and mission duration, increase dramatically with arcjet specific impulse in the 500-600 s range, but are nearly constant for the derated ion thruster operated in the 2300-3000 s range. For a given mission, the mass benefits with an ion system are typically double those of the arcjet system; however, the total thrusting time with arcjets is less than one-third that with ion thrusters for the same thruster power.

  14. Text chat as a tool for referential questioning in Asperger syndrome.

    PubMed

    Rajendran, Gnanathusharan; Mitchell, Peter

    2006-02-01

    This article reports a study in which referential communication in 11 individuals with Asperger syndrome (AS) and 11 controls was compared between text chat and telephone, using a route-solving task. Participants deduced routes by asking closed questions, and the dependent variables were (a) accuracy in working out the route, (b) number of questions posed (turns taken), and (c) time taken to complete the task. Generally, individuals with AS were equally competent in solving the task in both media but less efficient than the typically developing comparison group. Individuals with AS who had higher measured executive ability adopted a similar approach to the comparison group, asking about landmarks on the map to deduce the route taken. In contrast, AS participants with lower executive ability used an inefficient left/right questioning strategy, which occupied more time, required more conversational turns, and was associated with a higher rate of error. Individuals with AS, who also have problems of executive functioning, may have difficulty communicating with others to use a route-solving task.

  15. Prospective memory in adults with spina bifida

    PubMed Central

    Dennis, Maureen; Nelson, Rebekah; Jewell, Derryn; Fletcher, Jack M.

    2011-01-01

    Introduction Individuals with neurodevelopmental disorders have been observed to show accelerated cognitive aging or even dementia as early as 30 and 40 years of age. Memory deficits are an important component of age-related cognitive loss. Methods In this study, we investigated prospective memory, which is often impaired in aging, in a group of 32 adults with spina bifida meningomyelocele (SBM), including members of the oldest living cohort successfully treated with shunts to divert excess cerebrospinal fluid, ventriculomegaly, and hydrocephalus, who are now around 50 years of age. Seventeen typically developing adults provided a comparison group. Results The SBM and comparison groups differed in the prospective memory total score as well as in both time-based and event-based subscores. Prospective memory was impaired in both older and younger individuals with SBM. However, the percentage of individuals with impaired or poor prospective memory was three times higher in the older SBM group than in the younger SBM group. The results are considered in relation to specific features of the complex brain reorganization in SBM. PMID:20393850

  16. Empathic responsiveness of children and adolescents with high-functioning autism spectrum disorder.

    PubMed

    Scheeren, Anke M; Koot, Hans M; Mundy, Peter C; Mous, Larissa; Begeer, Sander

    2013-10-01

    Previous studies have shown reduced empathic responsiveness to others' emotions in preschoolers with autism spectrum disorder (ASD) and an intellectual disability. However, age and intelligence may promote children's empathic responsiveness. Therefore, we examined the empathic responsiveness in normally intelligent school-aged children and adolescents with a clinical diagnosis of ASD (n = 151) and in a typically developing comparison group (n = 50), using structured observations and parent reports. Based on the observations, participants' responses to the emotional displays of an interviewer were surprisingly similar. However, compared with parents from the comparison group, parents of a child with ASD reported significantly fewer empathic responses, particularly when the child received a high score on the Autism Diagnostic Observation Schedule. Even though parents report a reduced empathic responsiveness in school-aged children and adolescents with ASD, it may be difficult to find these empathic limitations during brief observations in a structured setting. © 2013 International Society for Autism Research, Wiley Periodicals, Inc.

  17. Microchannel plate special nuclear materials sensor

    NASA Astrophysics Data System (ADS)

    Feller, W. B.; White, P. L.; White, P. B.; Siegmund, O. H. W.; Martin, A. P.; Vallerga, J. V.

    2011-10-01

    Nova Scientific Inc., is developing for the Domestic Nuclear Detection Office (DNDO SBIR #HSHQDC-08-C-00190), a solid-state, high-efficiency neutron detection alternative to 3He gas tubes, using neutron-sensitive microchannel plates (MCPs) containing 10B and/or Gd. This work directly supports DNDO development of technologies designed to detect and interdict nuclear weapons or illicit nuclear materials. Neutron-sensitized MCPs have been shown theoretically and more recently experimentally, to be capable of thermal neutron detection efficiencies equivalent to 3He gas tubes. Although typical solid-state neutron detectors typically have an intrinsic gamma sensitivity orders of magnitude higher than that of 3He gas detectors, we dramatically reduce gamma sensitivity by combining a novel electronic coincidence rejection scheme, employing a separate but enveloping gamma scintillator. This has already resulted in a measured gamma rejection ratio equal to a small 3He tube, without in principle sacrificing neutron detection efficiency. Ongoing improvements to the MCP performance as well as the coincidence counting geometry will be described. Repeated testing and validation with a 252Cf source has been underway throughout the Phase II SBIR program, with ongoing comparisons to a small commercial 3He gas tube. Finally, further component improvements and efforts toward integration maturity are underway, with the goal of establishing functional prototypes for SNM field testing.

  18. Auditory attention in autism spectrum disorder: An exploration of volumetric magnetic resonance imaging findings.

    PubMed

    Lalani, Sanam J; Duffield, Tyler C; Trontel, Haley G; Bigler, Erin D; Abildskov, Tracy J; Froehlich, Alyson; Prigge, Molly B D; Travers, Brittany G; Anderson, Jeffrey S; Zielinski, Brandon A; Alexander, Andrew; Lange, Nicholas; Lainhart, Janet E

    2018-06-01

    Studies have shown that individuals with autism spectrum disorder (ASD) tend to perform significantly below typically developing individuals on standardized measures of attention, even when controlling for IQ. The current study sought to examine within ASD whether anatomical correlates of attention performance differed between those with average to above-average IQ (AIQ group) and those with low-average to borderline ability (LIQ group) as well as in comparison to typically developing controls (TDC). Using automated volumetric analyses, we examined regional volume of classic attention areas including the superior frontal gyrus, anterior cingulate cortex, and precuneus in ASD AIQ (n = 38) and LIQ (n = 18) individuals along with 30 TDC. Auditory attention performance was assessed using subtests of the Test of Memory and Learning (TOMAL) compared among the groups and then correlated with regional brain volumes. Analyses revealed group differences in attention. The three groups did not differ significantly on any auditory attention-related brain volumes; however, trends toward significant size-attention function interactions were observed. Negative correlations were found between the volume of the precuneus and auditory attention performance for the AIQ ASD group, indicating larger volume related to poorer performance. Implications for general attention functioning and dysfunctional neural connectivity in ASD are discussed.

  19. Prevalence of overweight and obesity among children and adolescents with intellectual disabilities: a systematic review and meta-analysis.

    PubMed

    Maïano, C; Hue, O; Morin, A J S; Moullec, G

    2016-07-01

    Although there have been numerous studies examining the prevalence of overweight and obesity among children and adolescents with intellectual disabilities, they have not yet been integrated and synthesized through a systematic quantitative review process. The purpose of this systematic review and meta-analysis was to determine: (i) the prevalence of overweight/obesity among children and adolescents with intellectual disabilities; (ii) the sources of heterogeneity in studies reporting the prevalence of overweight/obesity in this population; and (iii) the risk of overweight/obesity in this population compared with their typically developing peers. A systematic literature search was performed and 16 studies, published between 1985 and 2015, met the inclusion criteria. The resulting pooled prevalence estimates for overweight, overweight-obesity and obesity were respectively: (i) 15%, 30%, and 13%, in children; and (ii) 18%, 33%, and 15% in adolescents. Subgroup analyses showed significant variations in the pooled prevalence estimates as a function of geographical region, recruitment setting, additional diagnoses, and norms used to define overweight or obesity. The findings also showed adolescents with intellectual disabilities to be respectively 1.54 and 1.80 times more at risk of overweight-obesity and obesity than typically developing adolescents. Unfortunately, no such comparison is available for children. © 2016 World Obesity. © 2016 World Obesity.

  20. Arterial hypertension in children with hemolytic uremic syndrome after kidney transplantation.

    PubMed

    Hoenecke, Johannes; Hartmann, Hans; Melk, Anette

    2015-08-01

    The development of arterial hypertension after KTX is a well-known complication. HUS is a systemic disease associated with arterial hypertension during long-term follow-up. Our goal was to report on the severity of arterial hypertension after KTX in patients with typical and atypical HUS. We analyzed the course of 197 patients with HUS, of which 22 (n = 10 with typical HUS; n = 12 with atypical HUS) developed ESRF and received KTX as renal replacement therapy. We analyzed data from 1766 casual BP and 85 24-h ABPM measurements. In addition, we evaluated the used antihypertensive strategy. Comparison between the two patient groups revealed that patients with atypical HUS had significantly higher casual SBP-SDS and DBP-SDS values after KTX despite similar intensity of antihypertensive treatment. These data were supported by analysis of ABPM profiles showing comparable results for the interval 1-5 yr after KTX. Patients with atypical HUS had a greater severity of arterial hypertension despite similar treatment strategies and intensity of treatment. Our observation, even though in a small cohort, supports recent genetic studies showing arterial hypertension closely associated with HUS-causing mutations in patients with atypical HUS. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  1. Enhancing attachment security in the infants of women in a jail-diversion program.

    PubMed

    Cassidy, Jude; Ziv, Yair; Stupica, Brandi; Sherman, Laura J; Butler, Heidi; Karfgin, Andrea; Cooper, Glen; Hoffman, Kent T; Powell, Bert

    2010-07-01

    Pregnant female offenders face multiple adversities that make successful parenting difficult. As a result, their children are at risk of developing insecure attachment and attachment disorganization, both of which are associated with an increased likelihood of poor developmental outcomes. We evaluated the outcomes of participants in Tamar's Children, a 15-month jail-diversion intervention for pregnant, nonviolent offenders with a history of substance abuse. All women received extensive wrap-around social services as well as the Circle of Security Perinatal Protocol (Cooper, Hoffman, & Powell, 2003). We present data on 20 women and their infants who completed the full dosage of treatment (a residential-living phase from pregnancy until infant age six months and community-living phase until 12 months). Results indicated that (1) program infants had rates of attachment security and attachment disorganization comparable to rates typically found in low-risk samples (and more favorable than those typically found in high-risk samples); (2) program mothers had levels of maternal sensitivity comparable to mothers in an existing community comparison group; and (3) improvement over time emerged for maternal depressive symptomatology, but not other aspects of maternal functioning. Given the lack of a randomized control group, results are discussed in terms of the exploratory, program-development nature of the study.

  2. Comparison of auditory comprehension skills in children with cochlear implant and typically developing children.

    PubMed

    Mandal, Joyanta Chandra; Kumar, Suman; Roy, Sumit

    2016-12-01

    The main goal of this study was to obtain auditory comprehension skills of native Hindi speaking children with cochlear implant and typically developing children across the age of 3-7 years and compare the scores between two groups. A total of sixty Hindi speaking participants were selected for the study. They were divided into two groups- Group-A consisted of thirty children with normal hearing and Group-B thirty children using cochlear implants. To assess the auditory comprehension skills, Test of auditory comprehension in Hindi (TACH) was used. The participant was required to point to one of three pictures which would best correspond to the stimulus presented. Correct answers were scored as 1 and incorrect answers as 0. TACH was administered on for both groups. Independent t-test was applied and it was found that auditory comprehension scores of children using cochlear implant were significantly poorer than the score of children with normal hearing for all three subtests. Pearson's correlation coefficient revealed poor correlation between the scores of children with normal hearing and children using cochlear implant. The results of this study suggest that children using cochlear implant have poor auditory comprehension skills than children with normal hearing. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  3. Mother-child play: children with Down syndrome and typical development.

    PubMed

    Venuti, P; de Falco, S; Esposito, G; Bornstein, Marc H

    2009-07-01

    Child solitary and collaborative mother-child play with 21 children with Down syndrome and 33 mental-age-matched typically developing children were compared. In solitary play, children with Down syndrome showed less exploratory but similar symbolic play compared to typically developing children. From solitary to collaborative play, children with Down syndrome increased their exploratory play, attaining the same level as typically developing children. Pretense significantly increased from solitary to collaborative play only in typically developing children. Differences between mothers' play in the two groups mirrored those between their children. Both groups showed similar attunement and synchrony. Mothers contribute to the play development of children with Down syndrome through their own adaptation to their children's limitations and potentialities.

  4. Understanding minds: early cochlear implantation and the development of theory of mind in children with profound hearing impairment.

    PubMed

    Sundqvist, Annette; Lyxell, Björn; Jönsson, Radoslava; Heimann, Mikael

    2014-03-01

    The present study investigates how auditory stimulation from cochlear implants (CI) is associated with the development of Theory of Mind (ToM) in severely and profoundly hearing impaired children with hearing parents. Previous research has shown that deaf children of hearing parents have a delayed ToM development. This is, however, not always the case with deaf children of deaf parents, who presumably are immersed in a more vivid signing environment. Sixteen children with CI (4.25 to 9.5 years of age) were tested on measures of cognitive and emotional ToM, language and cognition. Eight of the children received their first implant relatively early (before 27 months) and half of them late (after 27 months). The two groups did not differ in age, gender, language or cognition at entry of the study. ToM tests included the unexpected location task and a newly developed Swedish social-emotional ToM test. The tests aimed to test both cognitive and emotional ToM. A comparison group of typically developing hearing age matched children was also added (n=18). Compared to the comparison group, the early CI-group did not differ in emotional ToM. The late CI-group differed significantly from the comparison group on both the cognitive and emotional ToM tests. The results revealed that children with early cochlear implants solved ToM problems to a significantly higher degree than children with late implants, although the groups did not differ on language or cognitive measures at baseline. The outcome suggests that early cochlear implantation for deaf children in hearing families, in conjunction with early social and communicative stimulation in a language that is native to the parents, can provide a foundation for a more normalized ToM development. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  5. Comparison of choose-a-movie and approach-avoidance paradigms to measure social motivation.

    PubMed

    Dubey, Indu; Ropar, Danielle; Hamilton, Antonia

    2018-01-01

    Social motivation is a subjective state which is rather difficult to quantify. It has sometimes been conceptualised as "behavioural effort" to seek social contact. Two paradigms: approach-avoidance (AA) and choose a movie (CAM), based on the same conceptualisation, have been used to measure social motivation in people with and without autism. However, in absence of a direct comparison, it is hard to know which of these paradigms has higher sensitivity in estimating preference for social over non-social stimuli. Here we compare these two tasks for their utility in (1) evaluating social seeking in typical people and (2) identifying the influence of autistic traits on social motivation. Our results suggest that CAM reveals a clear preference for social stimuli over non-social in typical adults but AA fails to do so. Also, social seeking measured with CAM but not AA has a negative relationship between autistic traits.

  6. KEY COMPARISON: CCQM-K21 Key Comparison Determination of pp’-DDT in fish oil

    NASA Astrophysics Data System (ADS)

    Webb, K. S.; Carter, D.; Wolff Briche, C. S. J.

    2003-01-01

    A key comparison on the determination of (pp'-dichlorodiphenyl) trichloroethane (pp'-DDT) in a fish oil matrix has been successfully completed. Nine NMIs participated in this key comparison and used the technique of isotope dilution gas-chromatography mass spectrometry (ID/GC/MS) for the determinations. Two samples (A and B) of fish oil were distributed to participants, each gravimetrically spiked with pp'-DDT. The KCRV for Sample A is 0.0743 +/- 0.0020 µg g-1 and that of Sample B is 0.1655 +/- 0.0014 µg g-1 of pp'-DDT in fish oil. The results for Sample A showed a RSD of 3.5%, the RSD for Sample B was within 1%. These results were an improvement over those of the corresponding pilot study (CCQM-P21), where at a mass fraction of pp'-DDT in fish oil of 0.311 µg g-1 the RSD was 2.6%. The compound pp'-DDT is a typical organochlorine pesticide and this key comparison has shown that NMIs have the ability to measure such compounds at levels typically found in the environment. The compound (pp'-dichlorodiphenyl) dichloroethylene (pp'-DDE), a metabolite of pp'-DDT, was the subject of a previous key comparison (CCQM-K5). The compound pp'-DDT is technically more challenging than that of pp'-DDE since it can decompose during the measurement procedure. Consequently the success of this key comparison, combined with that of CCQM-K5 demonstrates a broad measurement capability by NMIs for organochlorine compounds in the environment. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the Mutual Recognition Arrangement (MRA).

  7. Ef: Software for Nonrelativistic Beam Simulation by Particle-in-Cell Algorithm

    NASA Astrophysics Data System (ADS)

    Boytsov, A. Yu.; Bulychev, A. A.

    2018-04-01

    Understanding of particle dynamics is crucial in construction of electron guns, ion sources and other types of nonrelativistic beam devices. Apart from external guiding and focusing systems, a prominent role in evolution of such low-energy beams is played by particle-particle interaction. Numerical simulations taking into account these effects are typically accomplished by a well-known particle-in-cell method. In practice, for convenient work a simulation program should not only implement this method, but also support parallelization, provide integration with CAD systems and allow access to details of the simulation algorithm. To address the formulated requirements, development of a new open source code - Ef - has been started. It's current features and main functionality are presented. Comparison with several analytical models demonstrates good agreement between the numerical results and the theory. Further development plans are discussed.

  8. Development of the hard and soft constraints based optimisation model for unit sizing of the hybrid renewable energy system designed for microgrid applications

    NASA Astrophysics Data System (ADS)

    Sundaramoorthy, Kumaravel

    2017-02-01

    The hybrid energy systems (HESs) based electricity generation system has become a more attractive solution for rural electrification nowadays. Economically feasible and technically reliable HESs are solidly based on an optimisation stage. This article discusses about the optimal unit sizing model with the objective function to minimise the total cost of the HES. Three typical rural sites from southern part of India have been selected for the application of the developed optimisation methodology. Feasibility studies and sensitivity analysis on the optimal HES are discussed elaborately in this article. A comparison has been carried out with the Hybrid Optimization Model for Electric Renewable optimisation model for three sites. The optimal HES is found with less total net present rate and rate of energy compared with the existing method

  9. Patterns and Predictors of Language Development from 4 to 7 Years in Verbal Children With and Without Autism Spectrum Disorder.

    PubMed

    Brignell, Amanda; Williams, Katrina; Jachno, Kim; Prior, Margot; Reilly, Sheena; Morgan, Angela T

    2018-04-28

    This study used a prospective community-based sample to describe patterns and predictors of language development from 4 to 7 years in verbal children (IQ ≥ 70) with autism spectrum disorder (ASD; n = 26-27). Children with typical language (TD; n = 858-861) and language impairment (LI; n = 119) were used for comparison. Children with ASD and LI had similar mean language scores that were lower on average than children with TD. Similar proportions across all groups had declining, increasing and stable patterns. Language progressed at a similar rate for all groups, with progress influenced by IQ and language ability at 4 years rather than social communication skills or diagnosis of ASD. These findings inform advice for parents about language prognosis in ASD.

  10. Eye-movement patterns during nonsymbolic and symbolic numerical magnitude comparison and their relation to math calculation skills.

    PubMed

    Price, Gavin R; Wilkey, Eric D; Yeo, Darren J

    2017-05-01

    A growing body of research suggests that the processing of nonsymbolic (e.g. sets of dots) and symbolic (e.g. Arabic digits) numerical magnitudes serves as a foundation for the development of math competence. Performance on magnitude comparison tasks is thought to reflect the precision of a shared cognitive representation, as evidence by the presence of a numerical ratio effect for both formats. However, little is known regarding how visuo-perceptual processes are related to the numerical ratio effect, whether they are shared across numerical formats, and whether they relate to math competence independently of performance outcomes. The present study investigates these questions in a sample of typically developing adults. Our results reveal a pattern of associations between eye-movement measures, but not their ratio effects, across formats. This suggests that ratio-specific visuo-perceptual processing during magnitude processing is different across nonsymbolic and symbolic formats. Furthermore, eye movements are related to math performance only during symbolic comparison, supporting a growing body of literature suggesting symbolic number processing is more strongly related to math outcomes than nonsymbolic magnitude processing. Finally, eye-movement patterns, specifically fixation dwell time, continue to be negatively related to math performance after controlling for task performance (i.e. error rate and reaction time) and domain general cognitive abilities (IQ), suggesting that fluent visual processing of Arabic digits plays a unique and important role in linking symbolic number processing to formal math abilities. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Improved methods for distribution loss evaluation. Volume 1: analytic and evaluative techniques. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Flinn, D.G.; Hall, S.; Morris, J.

    This volume describes the background research, the application of the proposed loss evaluation techniques, and the results. The research identified present loss calculation methods as appropriate, provided care was taken to represent the various system elements in sufficient detail. The literature search of past methods and typical data revealed that extreme caution in using typical values (load factor, etc.) should be taken to ensure that all factors were referred to the same time base (daily, weekly, etc.). The performance of the method (and computer program) proposed in this project was determined by comparison of results with a rigorous evaluation ofmore » losses on the Salt River Project system. This rigorous evaluation used statistical modeling of the entire system as well as explicit enumeration of all substation and distribution transformers. Further tests were conducted at Public Service Electric and Gas of New Jersey to check the appropriateness of the methods in a northern environment. Finally sensitivity tests indicated data elements inaccuracy of which would most affect the determination of losses using the method developed in this project.« less

  12. Value Production in a Collaborative Environment. Sociophysical Studies of Wikipedia

    NASA Astrophysics Data System (ADS)

    Yasseri, Taha; Kertész, János

    2013-05-01

    We review some recent endeavors and add some new results to characterize and understand underlying mechanisms in Wikipedia (WP), the paradigmatic example of collaborative value production. We analyzed the statistics of editorial activity in different languages and observed typical circadian and weekly patterns, which enabled us to estimate the geographical origins of contributions to WPs in languages spoken in several time zones. Using a recently introduced measure we showed that the editorial activities have intrinsic dependencies in the burstiness of events. A comparison of the English and Simple English WPs revealed important aspects of language complexity and showed how peer cooperation solved the task of enhancing readability. One of our focus issues was characterizing the conflicts or edit wars in WPs, which helped us to automatically filter out controversial pages. When studying the temporal evolution of the controversiality of such pages we identified typical patterns and classified conflicts accordingly. Our quantitative analysis provides the basis of modeling conflicts and their resolution in collaborative environments and contribute to the understanding of this issue, which becomes increasingly important with the development of information communication technology.

  13. Time-domain hybrid method for simulating large amplitude motions of ships advancing in waves

    NASA Astrophysics Data System (ADS)

    Liu, Shukui; Papanikolaou, Apostolos D.

    2011-03-01

    Typical results obtained by a newly developed, nonlinear time domain hybrid method for simulating large amplitude motions of ships advancing with constant forward speed in waves are presented. The method is hybrid in the way of combining a time-domain transient Green function method and a Rankine source method. The present approach employs a simple double integration algorithm with respect to time to simulate the free-surface boundary condition. During the simulation, the diffraction and radiation forces are computed by pressure integration over the mean wetted surface, whereas the incident wave and hydrostatic restoring forces/moments are calculated on the instantaneously wetted surface of the hull. Typical numerical results of application of the method to the seakeeping performance of a standard containership, namely the ITTC S175, are herein presented. Comparisons have been made between the results from the present method, the frequency domain 3D panel method (NEWDRIFT) of NTUA-SDL and available experimental data and good agreement has been observed for all studied cases between the results of the present method and comparable other data.

  14. Brief report: atypical neuromagnetic responses to illusory auditory pitch in children with autism spectrum disorders.

    PubMed

    Brock, Jon; Bzishvili, Samantha; Reid, Melanie; Hautus, Michael; Johnson, Blake W

    2013-11-01

    Atypical auditory perception is a widely recognised but poorly understood feature of autism. In the current study, we used magnetoencephalography to measure the brain responses of 10 autistic children as they listened passively to dichotic pitch stimuli, in which an illusory tone is generated by sub-millisecond inter-aural timing differences in white noise. Relative to control stimuli that contain no inter-aural timing differences, dichotic pitch stimuli typically elicit an object related negativity (ORN) response, associated with the perceptual segregation of the tone and the carrier noise into distinct auditory objects. Autistic children failed to demonstrate an ORN, suggesting a failure of segregation; however, comparison with the ORNs of age-matched typically developing controls narrowly failed to attain significance. More striking, the autistic children demonstrated a significant differential response to the pitch stimulus, peaking at around 50 ms. This was not present in the control group, nor has it been found in other groups tested using similar stimuli. This response may be a neural signature of atypical processing of pitch in at least some autistic individuals.

  15. Integrating Physical and Topographic Information Into a Fuzzy Scheme to Map Flooded Area by SAR.

    PubMed

    Pierdicca, Nazzareno; Chini, Marco; Pulvirenti, Luca; Macina, Flavia

    2008-07-10

    A flood mapping procedure based on a fuzzy sets theory has been developed. The method is based on the integration of Synthetic Aperture Radar (SAR) measurements with additional data on the inundated area, such as a land cover map and a digital elevation model (DEM). The information on land cover has allowed us to account for both specular reflection, typical of open water, and double bounce backscattering, typical of forested and urban areas. DEM has been exploited to include simple hydraulic considerations on the dependence of inundation probability on surface characteristics. Contextual information has been taken into account too. The proposed algorithm has been tested on a flood occurred in Italy on November 1994. A pair of ERS-1 images, collected before and after (three days later) the flood, has been used. The results have been compared with the data provided by a ground survey carried out when the flood reached its maximum extension. Despite the temporal mismatch between the survey and the post-inundation SAR image, the comparison has yielded encouraging results, with the 87% of the pixels correctly classified as inundated.

  16. An integrated framework for the optimisation of sport and athlete development: a practitioner approach.

    PubMed

    Gulbin, Jason P; Croser, Morag J; Morley, Elissa J; Weissensteiner, Juanita R

    2013-01-01

    This paper introduces a new sport and athlete development framework that has been generated by multidisciplinary sport practitioners. By combining current theoretical research perspectives with extensive empirical observations from one of the world's leading sport agencies, the proposed FTEM (Foundations, Talent, Elite, Mastery) framework offers broad utility to researchers and sporting stakeholders alike. FTEM is unique in comparison with alternative models and frameworks, because it: integrates general and specialised phases of development for participants within the active lifestyle, sport participation and sport excellence pathways; typically doubles the number of developmental phases (n = 10) in order to better understand athlete transition; avoids chronological and training prescriptions; more optimally establishes a continuum between participation and elite; and allows full inclusion of many developmental support drivers at the sport and system levels. The FTEM framework offers a viable and more flexible alternative for those sporting stakeholders interested in managing, optimising, and researching sport and athlete development pathways.

  17. Symbolic and non-symbolic number magnitude processing in children with developmental dyscalculia.

    PubMed

    Castro Cañizares, Danilka; Reigosa Crespo, Vivian; González Alemañy, Eduardo

    2012-11-01

    The aim of this study was to evaluate if children with Developmental Dyscalculia (DD) exhibit a general deficit in magnitude representations or a specific deficit in the connection of symbolic representations with the corresponding analogous magnitudes. DD was diagnosed using a timed arithmetic task. The experimental magnitude comparison tasks were presented in non-symbolic and symbolic formats. DD and typically developing (TD) children showed similar numerical distance and size congruity effects. However, DD children performed significantly slower in the symbolic task. These results are consistent with the access deficit hypothesis, according to which DD children's deficits are caused by difficulties accessing magnitude information from numerical symbols rather than in processing numerosities per se.

  18. Cultural Differences in Donation Decision-Making

    PubMed Central

    Wang, Jinjun

    2015-01-01

    Decisions to help those in need are essential for human development and survival. Previous studies have demonstrated the “identified effect”, in which one identifiable individual typically invokes stronger feelings of compassion and receives greater aid than statistical victim. However, this preference might be influenced by cultural differences. In the current study, Chinese respondents’ ratings of distress and sympathy and their willingness to contribute are greater for a group of sick children than an individual. In the U.S., greater willingness to help and sympathy are elicited by an identified victim in comparison with an unidentified one. The different results may demonstrate the importance of cultural differences when trying to understand people’s prosocial behavior. PMID:26372014

  19. Stall flutter analysis of propfans

    NASA Technical Reports Server (NTRS)

    Reddy, T. S. R.

    1988-01-01

    Three semi-empirical aerodynamic stall models are compared with respect to their lift and moment hysteresis loop prediction, limit cycle behavior, easy implementation, and feasibility in developing the parameters required for stall flutter prediction of advanced turbines. For the comparison of aeroelastic response prediction including stall, a typical section model and a plate structural model are considered. The response analysis includes both plunging and pitching motions of the blades. In model A, a correction of the angle of attack is applied when the angle of attack exceeds the static stall angle. In model B, a synthesis procedure is used for angles of attack above static stall angles, and the time history effects are accounted for through the Wagner function.

  20. Comparison of methods for determining the numbers and species distribution of coliform bacteria in well water samples.

    PubMed

    Niemi, R M; Heikkilä, M P; Lahti, K; Kalso, S; Niemelä, S I

    2001-06-01

    Enumeration of coliform bacteria and Escherichia coli is the most widely used method in the estimation of hygienic quality of drinking water. The yield of target bacteria and the species composition of different populations of coliform bacteria may depend on the method.Three methods were compared. Three membrane filtration methods were used for the enumeration of coliform bacteria in shallow well waters. The yield of confirmed coliform bacteria was highest on Differential Coliform agar, followed by LES Endo agar. Differential Coliform agar had the highest proportion of typical colonies, of which 74% were confirmed as belonging to the Enterobacteriaceae. Of the typical colonies on Lactose Tergitol 7 TTC agar, 75% were confirmed as Enterobacteriaceae, whereas 92% of typical colonies on LES Endo agar belonged to the Enterobacteriaceae. LES Endo agar yielded many Serratia strains, Lactose Tergitol 7 TTC agar yielded numerous strains of Rahnella aquatilis and Enterobacter, whereas Differential Coliform agar yielded the widest range of species. The yield of coliform bacteria varied between methods. Each method compared had a characteristic species distribution of target bacteria and a typical level of interference of non-target bacteria. Identification with routine physiological tests to distinct species was hampered by the slight differences between species. High yield and sufficient selectivity are difficult to achieve simultaneously, especially if the target group is diverse. The results showed that several aspects of method performance should be considered, and that the target group must be distinctly defined to enable method comparisons.

  1. Optimal Threshold Determination for Interpreting Semantic Similarity and Particularity: Application to the Comparison of Gene Sets and Metabolic Pathways Using GO and ChEBI

    PubMed Central

    Bettembourg, Charles; Diot, Christian; Dameron, Olivier

    2015-01-01

    Background The analysis of gene annotations referencing back to Gene Ontology plays an important role in the interpretation of high-throughput experiments results. This analysis typically involves semantic similarity and particularity measures that quantify the importance of the Gene Ontology annotations. However, there is currently no sound method supporting the interpretation of the similarity and particularity values in order to determine whether two genes are similar or whether one gene has some significant particular function. Interpretation is frequently based either on an implicit threshold, or an arbitrary one (typically 0.5). Here we investigate a method for determining thresholds supporting the interpretation of the results of a semantic comparison. Results We propose a method for determining the optimal similarity threshold by minimizing the proportions of false-positive and false-negative similarity matches. We compared the distributions of the similarity values of pairs of similar genes and pairs of non-similar genes. These comparisons were performed separately for all three branches of the Gene Ontology. In all situations, we found overlap between the similar and the non-similar distributions, indicating that some similar genes had a similarity value lower than the similarity value of some non-similar genes. We then extend this method to the semantic particularity measure and to a similarity measure applied to the ChEBI ontology. Thresholds were evaluated over the whole HomoloGene database. For each group of homologous genes, we computed all the similarity and particularity values between pairs of genes. Finally, we focused on the PPAR multigene family to show that the similarity and particularity patterns obtained with our thresholds were better at discriminating orthologs and paralogs than those obtained using default thresholds. Conclusion We developed a method for determining optimal semantic similarity and particularity thresholds. We applied this method on the GO and ChEBI ontologies. Qualitative analysis using the thresholds on the PPAR multigene family yielded biologically-relevant patterns. PMID:26230274

  2. A personal rapid transit/airport automated people mover comparison.

    DOT National Transportation Integrated Search

    2008-01-01

    Airport automated people movers (AAPM) typically consist of driverless trains with : up to about four cars each capable of carrying 20 to 100 passengers who are mostly : standing. They have been successfully used for surface transportation in airport...

  3. Metamodels for Ozone - Comparison of Two Techniques

    EPA Science Inventory

    A metamodel is a mathematical relationship between the inputs and outputs of a simulation experiment, permitting calculation of outputs for scenarios of interest without having to run new (presumably costly) experiments. Ozone metamodels are typically designed to capture a parti...

  4. Selective Self-Presentation and Social Comparison Through Photographs on Social Networking Sites.

    PubMed

    Fox, Jesse; Vendemia, Megan A

    2016-10-01

    Through social media and camera phones, users enact selective self-presentation as they choose, edit, and post photographs of themselves (such as selfies) to social networking sites for an imagined audience. Photos typically focus on users' physical appearance, which may compound existing sociocultural pressures about body image. We identified users of social networking sites among a nationally representative U.S. sample (N = 1,686) and examined women's and men's photo-related behavior, including posting photos, editing photos, and feelings after engaging in upward and downward social comparison with others' photos on social networking sites. We identified some sex differences: women edited photos more frequently and felt worse after upward social comparison than men. Body image and body comparison tendency mediated these effects.

  5. A comparison of multi-metal deposition processes utilising gold nanoparticles and an evaluation of their application to 'low yield' surfaces for finger mark development.

    PubMed

    Fairley, C; Bleay, S M; Sears, V G; NicDaeid, N

    2012-04-10

    This paper reports a comparison of the effectiveness and practicality of using different multi-metal deposition processes for finger mark development. The work investigates whether modifications can be made to improve the performance of the existing process published by Schnetz. Secondly, we compare the ability of different multi-metal deposition processes to develop finger marks on a range of surfaces with that of other currently used development processes. All published multi-metal deposition processes utilise an initial stage of colloidal gold deposition followed by enhancement of the marks with using a physical developer. All possible combinations of colloidal gold and physical developer stages were tested. The method proposed by Schnetz was shown to be the most effective process, however a modification which reduced the pH of the enhancement solution was revealed to provide the best combination of effectiveness and practicality. In trials comparing the modified formulation with vacuum metal deposition, superglue and powder suspensions on surfaces which typically give low finger mark yields (cling film, plasticised vinyl, leather and masking tape), the modified method produced significantly better results over existing processes for cling film and plasticised vinyl. The modified formulation was found to be ineffective on both masking tape and leather. It is recommended that further tests be carried out on the modified multi-metal deposition formulation to establish whether it could be introduced for operational work on cling film material in particular. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  6. Spelling Well Despite Developmental Language Disorder: What Makes it Possible?

    PubMed Central

    Rakhlin, Natalia; Cardoso-Martins, Cláudia; Kornilov, Sergey A.; Grigorenko, Elena L.

    2013-01-01

    The goal of the study was to investigate the overlap between Developmental Language Disorder (DLD) and Developmental Dyslexia, identified through spelling difficulties (SD), in Russian-speaking children. In particular, we studied the role of phoneme awareness (PA), rapid automatized naming (RAN), pseudoword repetition (PWR), morphological (MA) and orthographic awareness (OA) in differentiating between children with DLD who have SD from children with DLD who are average spellers by comparing the two groups to each other, to typically developing children as well as children with SD but without spoken language deficits. One hundred forty nine children, aged 10.40 to 14.00, participated in the study. The results indicated that the SD, DLD, and DLD/SD groups did not differ from each other on PA and RAN Letters and underperformed in comparison to the control groups. However, whereas the children with written language deficits (SD and DLD/SD groups) underperformed on RAN Objects and Digits, PWR, OA and MA, the children with DLD and no SD performed similarly to the children from the control groups on these measures. In contrast, the two groups with spoken language deficits (DLD and DLD/SD) underperformed on RAN Colors in comparison to the control groups and the group of children with SD only. The results support the notion that those children with DLD who have unimpaired PWR and RAN skills are able to overcome their weaknesses in spoken language and PA and acquire basic literacy on a par with their age peers with typical language. We also argue that our findings support a multifactorial model of developmental language disorders (DLD). PMID:23860907

  7. Enhanced pure-tone pitch discrimination among persons with autism but not Asperger syndrome.

    PubMed

    Bonnel, Anna; McAdams, Stephen; Smith, Bennett; Berthiaume, Claude; Bertone, Armando; Ciocca, Valter; Burack, Jacob A; Mottron, Laurent

    2010-07-01

    Persons with Autism spectrum disorders (ASD) display atypical perceptual processing in visual and auditory tasks. In vision, Bertone, Mottron, Jelenic, and Faubert (2005) found that enhanced and diminished visual processing is linked to the level of neural complexity required to process stimuli, as proposed in the neural complexity hypothesis. Based on these findings, Samson, Mottron, Jemel, Belin, and Ciocca (2006) proposed to extend the neural complexity hypothesis to the auditory modality. They hypothesized that persons with ASD should display enhanced performance for simple tones that are processed in primary auditory cortical regions, but diminished performance for complex tones that require additional processing in associative auditory regions, in comparison to typically developing individuals. To assess this hypothesis, we designed four auditory discrimination experiments targeting pitch, non-vocal and vocal timbre, and loudness. Stimuli consisted of spectro-temporally simple and complex tones. The participants were adolescents and young adults with autism, Asperger syndrome, and typical developmental histories, all with IQs in the normal range. Consistent with the neural complexity hypothesis and enhanced perceptual functioning model of ASD (Mottron, Dawson, Soulières, Hubert, & Burack, 2006), the participants with autism, but not with Asperger syndrome, displayed enhanced pitch discrimination for simple tones. However, no discrimination-thresholds differences were found between the participants with ASD and the typically developing persons across spectrally and temporally complex conditions. These findings indicate that enhanced pure-tone pitch discrimination may be a cognitive correlate of speech-delay among persons with ASD. However, auditory discrimination among this group does not appear to be directly contingent on the spectro-temporal complexity of the stimuli. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  8. COMBINED 24-HOURS ESOPHAGEAL PH MONITORING AND MULTICHANNEL INTRALUMINAL IMPEDANCE FOR COMPARISON OF GASTROESOPHAGEAL REFLUX IN CHILDREN WITH TYPICAL VERSUS ATYPICAL SYMPTOMS OF GASTROESOPHAGEAL REFLUX DISEASE.

    PubMed

    Dehghani, Seyed Mohsen; Taghavi, Seyed Alireza; Javaherizadeh, Hazhir; Nasri, Maryam

    2016-01-01

    - Gastroesophageal reflux disease is the most common esophageal disorder in pediatrics. - The aim of this study was to compare reflux parameters of typical and atypical symptoms of gastroesophageal reflux disease using 24-hour esophageal pH monitoring and multichannel intraluminal impedance in pediatric population. - In this prospective study, 43 patients aged less than 18 year with suspected gastroesophageal reflux disease were enrolled. The patients were divided into two groups based on the main presenting symptoms (typical versus atypical). Twenty four-hour pH monitoring and multichannel intraluminal impedance were performed in all the patients for comparing these two group regarding association of symptoms and reflux. Number of refluxes, pH related reflux, total reflux time, reflux more than 5 minutes, longest time of the reflux, lowest pH at reflux, reflux index were recorded and compared. Data comparison was done using SPSS. - The mean age of the patients was 5.7±3.4 years and 65.1% were male. Out of 43 patients 24 cases had typical symptoms and 19 had atypical symptoms. The mean reflux events detected by multichannel intraluminal impedance was more than mean reflux events detected by pH monitoring (308.4±115.8 vs 69.7±66.6) with P value of 0.037, which is statistically significant. The mean symptom index and symptom association probability were 35.01% ± 20.78% and 86.42% ± 25.79%, respectively in multichannel intraluminal impedance versus 12.73% ± 12.48% and 45.16% ± 42.29% in pH monitoring (P value <0.001). Number of acid reflux was 46.26±47.16 and 30.9±22.09 for atypical and typical symptoms respectively. The mean symptom index was 18.12% ± 13.101% and 8.30% ± 10.301% in atypical and typical symptoms respectively (P=0.034). Bolus clearance was longer in atypical symptoms compared typical symptoms(P<0.05). - Symptom index was significantly higher in atypical symptoms compared to typical symptoms. Higher number of acid reflux was found in children with atypical symptoms of reflux. Longer duration of bolus clearance was found in group with atypical symptoms of reflux.

  9. Simplified three microphone acoustic test method

    USDA-ARS?s Scientific Manuscript database

    Accepted acoustic testing standards are available; however, they require specialized hardware and software that are typically out of reach economically to the occasional practitioner. What is needed is a simple and inexpensive screening method that could provide a quick comparison for rapid identifi...

  10. Vacuum ultraviolet line radiation measurements of a shock-heated nitrogen plasma

    NASA Technical Reports Server (NTRS)

    Mcclenahan, J. O.

    1972-01-01

    Line radiation, in the wavelength region from 1040 to 2500 A from nitrogen plasmas, was measured at conditions typical of those produced in the shock layer in front of vehicles entering the earth's atmosphere at superorbital velocities. The radiation was also predicted with a typical radiation transport computer program to determine whether such calculations adequately model plasmas for the conditions tested. The results of the comparison show that the radiant intensities of the lines between 1040 and 1700 A are actually lower than are predicted by such computer models.

  11. Water Sampling While Under Way , Proceedings of a Symposium and Workshops, February 11-12, 1980.

    DTIC Science & Technology

    1980-01-01

    W, and consequently W/R, will be small. To illustrate these points, values of kl, kA , and W are comparedin Table 1 for a typical, round, galvanized...7 TABLE I COMPARISON OF SAMPLER CABLE AND TYPICAL ELECTROMECHANICAL CABLE Characteristic k1 kA k W Electromechanical 0.40 1 0.40 1.5 t 2 Sampler...configurations obviously do not suffer in static (i.e., constant speed) performance since the factors k1 and kA are the same with or without the voids, assuming

  12. How Autism Affects Speech Understanding in Multitalker Environments

    DTIC Science & Technology

    2013-10-01

    difficult than will typically- developing children. Knowing whether toddlers with ASD have difficulties processing speech in the presence of acoustic...to separate the speech of different talkers than do their typically- developing peers. We also predict that they will fail to exploit visual cues on...learn language from many settings in which children are typically placed. In addition, one of the cues that typically- developing listeners use to

  13. An Approach for Determining Quantitative Measures for Bone Volume and Bone Mass in the Pediatric Spina Bifida Population

    PubMed Central

    Horenstein, Rachel E.; Shefelbine, Sandra J.; Mueske, Nicole M.; Fisher, Carissa L.; Wren, Tishya A.L.

    2015-01-01

    Background The pediatric spina bifida population suffers from decreased mobility and recurrent fractures. This study aimed to develop a method for quantifying bone mass along the entire tibia in youth with spina bifida. This will provide information about all potential sites of bone deficiencies. Methods Computed tomography images of the tibia for 257 children (n=80 ambulatory spina bifida, n=10 non-ambulatory spina bifida, n=167 typically developing) were analyzed. Bone area was calculated at regular intervals along the entire tibia length and then weighted by calibrated pixel intensity for density weighted bone area. Integrals of density weighted bone area were used to quantify bone mass in the proximal and distal epiphyses and diaphysis. Group differences were evaluated using analysis of variance. Findings Non-ambulatory children suffer from decreased bone mass in the diaphysis and proximal and distal epiphyses compared to ambulatory and control children (P≤0.001). Ambulatory children with spina bifida showed statistically insignificant differences in bone mass in comparison to typically developing children at these sites (P>0.5). Interpretation This method provides insight into tibial bone mass distribution in the pediatric spina bifida population by incorporating information along the whole length of the bone, thereby providing more information than dual-energy x-ray absorptiometry and peripheral quantitative computed tomography. This method can be applied to any population to assess bone mass distribution across the length of any long bone. PMID:26002057

  14. Diagnosing Developmental Dyscalculia on the Basis of Reliable Single Case FMRI Methods: Promises and Limitations

    PubMed Central

    Dinkel, Philipp Johannes; Willmes, Klaus; Krinzinger, Helga; Konrad, Kerstin; Koten Jr, Jan Willem

    2013-01-01

    FMRI-studies are mostly based on a group study approach, either analyzing one group or comparing multiple groups, or on approaches that correlate brain activation with clinically relevant criteria or behavioral measures. In this study we investigate the potential of fMRI-techniques focusing on individual differences in brain activation within a test-retest reliability context. We employ a single-case analysis approach, which contrasts dyscalculic children with a control group of typically developing children. In a second step, a support-vector machine analysis and cluster analysis techniques served to investigate similarities in multivariate brain activation patterns. Children were confronted with a non-symbolic number comparison and a non-symbolic exact calculation task during fMRI acquisition. Conventional second level group comparison analysis only showed small differences around the angular gyrus bilaterally and the left parieto-occipital sulcus. Analyses based on single-case statistical procedures revealed that developmental dyscalculia is characterized by individual differences predominantly in visual processing areas. Dyscalculic children seemed to compensate for relative under-activation in the primary visual cortex through an upregulation in higher visual areas. However, overlap in deviant activation was low for the dyscalculic children, indicating that developmental dyscalculia is a disorder characterized by heterogeneous brain activation differences. Using support vector machine analysis and cluster analysis, we tried to group dyscalculic and typically developing children according to brain activation. Fronto-parietal systems seem to qualify for a distinction between the two groups. However, this was only effective when reliable brain activations of both tasks were employed simultaneously. Results suggest that deficits in number representation in the visual-parietal cortex get compensated for through finger related aspects of number representation in fronto-parietal cortex. We conclude that dyscalculic children show large individual differences in brain activation patterns. Nonetheless, the majority of dyscalculic children can be differentiated from controls employing brain activation patterns when appropriate methods are used. PMID:24349547

  15. Diagnosing developmental dyscalculia on the basis of reliable single case FMRI methods: promises and limitations.

    PubMed

    Dinkel, Philipp Johannes; Willmes, Klaus; Krinzinger, Helga; Konrad, Kerstin; Koten, Jan Willem

    2013-01-01

    FMRI-studies are mostly based on a group study approach, either analyzing one group or comparing multiple groups, or on approaches that correlate brain activation with clinically relevant criteria or behavioral measures. In this study we investigate the potential of fMRI-techniques focusing on individual differences in brain activation within a test-retest reliability context. We employ a single-case analysis approach, which contrasts dyscalculic children with a control group of typically developing children. In a second step, a support-vector machine analysis and cluster analysis techniques served to investigate similarities in multivariate brain activation patterns. Children were confronted with a non-symbolic number comparison and a non-symbolic exact calculation task during fMRI acquisition. Conventional second level group comparison analysis only showed small differences around the angular gyrus bilaterally and the left parieto-occipital sulcus. Analyses based on single-case statistical procedures revealed that developmental dyscalculia is characterized by individual differences predominantly in visual processing areas. Dyscalculic children seemed to compensate for relative under-activation in the primary visual cortex through an upregulation in higher visual areas. However, overlap in deviant activation was low for the dyscalculic children, indicating that developmental dyscalculia is a disorder characterized by heterogeneous brain activation differences. Using support vector machine analysis and cluster analysis, we tried to group dyscalculic and typically developing children according to brain activation. Fronto-parietal systems seem to qualify for a distinction between the two groups. However, this was only effective when reliable brain activations of both tasks were employed simultaneously. Results suggest that deficits in number representation in the visual-parietal cortex get compensated for through finger related aspects of number representation in fronto-parietal cortex. We conclude that dyscalculic children show large individual differences in brain activation patterns. Nonetheless, the majority of dyscalculic children can be differentiated from controls employing brain activation patterns when appropriate methods are used.

  16. Neuroanatomic alterations and social and communication deficits in monozygotic twins discordant for autism disorder.

    PubMed

    Mitchell, Shanti R; Reiss, Allan L; Tatusko, Danielle H; Ikuta, Ichiro; Kazmerski, Dana B; Botti, Jo-Anna C; Burnette, Courtney P; Kates, Wendy R

    2009-08-01

    Investigating neuroanatomic differences in monozygotic twins who are discordant for autism can help unravel the relative contributions of genetics and environment to this pervasive developmental disorder. The authors used magnetic resonance imaging (MRI) to investigate several brain regions of interest in monozygotic twins who varied in degree of phenotypic discordance for narrowly defined autism. The subjects were 14 pairs of monozygotic twins between the ages of 5 and 14 years old and 14 singleton age- and gender-matched typically developing comparison subjects. The monozygotic twin group was a cohort of children with narrowly defined autistic deficits and their co-twins who presented with varying levels of autistic deficits. High-resolution MRIs were acquired and volumetric/area measurements obtained for the frontal lobe, amygdala, and hippocampus and subregions of the prefrontal cortex, corpus callosum, and cerebellar vermis. No neurovolumetric/area differences were found between twin pairs. Relative to typically developing comparison subjects, dorsolateral prefrontal cortex volumes and anterior areas of the corpus callosum were significantly altered in autistic twins, and volumes of the posterior vermis were altered in both autistic twins and co-twins. Intraclass correlation analysis of brain volumes between children with autism and their co-twins indicated that the degree of within-pair neuroanatomic concordance varied with brain region. In the group of subjects with narrowly defined autism only, dorsolateral prefrontal cortex, amygdala, and posterior vermis volumes were significantly associated with the severity of autism based on scores from the Autism Diagnostic Observation Schedule-Generic. These findings support previous research demonstrating alterations in the prefrontal cortex, corpus callosum, and posterior vermis in children with autism and further suggest that alterations are associated with the severity of the autism phenotype. Continued research involving twins who are concordant and discordant for autism is essential to disentangle the genetic and environmental contributions to autism.

  17. Comparisons of IQ in Children With and Without Cochlear Implants: Longitudinal Findings and Associations With Language.

    PubMed

    Cejas, Ivette; Mitchell, Christine M; Hoffman, Michael; Quittner, Alexandra L

    2018-04-05

    To make longitudinal comparisons of intelligence quotient (IQ) in children with cochlear implants (CIs) and typical hearing peers from early in development to the school-age period. Children with additional comorbidities and CIs were also evaluated. To estimate the impact of socioeconomic status and oral language on school-age cognitive performance. This longitudinal study evaluated nonverbal IQ in a multicenter, national sample of 147 children with CIs and 75 typically hearing peers. IQ was evaluated at baseline, prior to cochlear implantation, using the Bayley Scales of Infant and Toddler Development and the Leiter International Performance Scale. School-age IQ was assessed using the Wechsler Intelligence Scales for Children. For the current study, only the Perceptual Reasoning and Processing Speed indices were administered. Oral language was evaluated using the Comprehensive Assessment of Spoken Language. Children in the CI group scored within the normal range of intelligence at both time points. However, children with additional comorbidities scored significantly worse on the Processing Speed, but not the Perceptual Reasoning Index. Maternal education and language were significantly related to school-age IQ in both groups. Importantly, language was the strongest predictor of intellectual functioning in both children with CIs and normal hearing. These results suggest that children using cochlear implants perform similarly to hearing peers on measures of intelligence, but those with severe comorbidities are at-risk for cognitive deficits. Despite the strong link between socioeconomic status and intelligence, this association was no longer significant once spoken language performance was accounted for. These results reveal the important contributions that early intervention programs, which emphasize language and parent training, contribute to cognitive functioning in school-age children with CIs. For families from economically disadvantaged backgrounds, who are at-risk for suboptimal outcomes, these early intervention programs are critical to improve overall functioning.

  18. International Comparison of Water Resources Utilization Efficiency in the Silk Road Economic Belt

    NASA Astrophysics Data System (ADS)

    Yan, Long; Ma, Jing; Deng, Wei; Wang, Yong

    2018-03-01

    In order to get knowledge of the standard of water utilization of the Silk Road Economic Belt from international point of view, the paper analyzes the annual variation of water resources utilization in the Silk Road Economic Belt, and compares with other typical countries. The study shows that Water resources utilization efficiency has been greatly improved in recent 20 years and the water consumption per USD 10000 of GDP has been declined 87.97%. the improvement of industrial water consumption efficiency is the key driving factors for substantial decrease in water consumption.The comparison of water utilization and human development shows that the higher HDI the country is, the more efficient water utilization the country has. water consumption per USD 10000 of GDP in country with HDI>0.9 is 194m³, being 8.5% of that in country with HDI from 0.5 to 0.6. On the premise of maintaining the stable economic and social development of the Silk Road Economic Belt, the realization of the control target of total water consumption must depend on the strict control over the disorderly expansion of irrigated area, the change in the mode of economic growth, the implementation of the development strategy for new industrialization and urbanization, vigorous development of the processing industry with low water consumption as well as the high-tech and high value-added industry. Only in this way, the control target of total water consumption can be realized in the process of completing the industrialization task.

  19. Recognition of Emotion from Facial Expressions with Direct or Averted Eye Gaze and Varying Expression Intensities in Children with Autism Disorder and Typically Developing Children

    PubMed Central

    Tell, Dina; Davidson, Denise; Camras, Linda A.

    2014-01-01

    Eye gaze direction and expression intensity effects on emotion recognition in children with autism disorder and typically developing children were investigated. Children with autism disorder and typically developing children identified happy and angry expressions equally well. Children with autism disorder, however, were less accurate in identifying fear expressions across intensities and eye gaze directions. Children with autism disorder rated expressions with direct eyes, and 50% expressions, as more intense than typically developing children. A trend was also found for sad expressions, as children with autism disorder were less accurate in recognizing sadness at 100% intensity with direct eyes than typically developing children. Although the present research showed that children with autism disorder are sensitive to eye gaze direction, impairments in the recognition of fear, and possibly sadness, exist. Furthermore, children with autism disorder and typically developing children perceive the intensity of emotional expressions differently. PMID:24804098

  20. Potential end-to-end imaging information rate advantages of various alternative communication systems

    NASA Technical Reports Server (NTRS)

    Rice, R. F.

    1978-01-01

    Various communication systems were considered which are required to transmit both imaging and a typically error sensitive, class of data called general science/engineering (gse) over a Gaussian channel. The approach jointly treats the imaging and gse transmission problems, allowing comparisons of systems which include various channel coding and data compression alternatives. Actual system comparisons include an Advanced Imaging Communication System (AICS) which exhibits the rather significant potential advantages of sophisticated data compression coupled with powerful yet practical channel coding.

  1. Exploring Typical and Atypical Safety Climate Perceptions of Practitioners in the Repair, Maintenance, Minor Alteration and Addition (RMAA) Sector in Hong Kong.

    PubMed

    Hon, Carol K H; Liu, Yulin

    2016-09-22

    The safety of repair, maintenance, minor alteration and addition (RMAA) work is an under-explored area. This study explored the typical and atypical safety climate perceptions of practitioners in the RMAA sector in Hong Kong, based on a self-administered questionnaire survey of 662 local practitioners in the industry. Profile analysis, via multidimensional scaling of the respondents' scores of three safety climate scales, identified one typical perception: high in management commitment to occupational health and safety (OHS) and employee involvement, low in applicability for safety rules and regulations, and low in responsibility for OHS. The respondents were clustered into typical and atypical perception groups according to their safety climate scores' match to the typical perception. A comparison of demographics between the two groups with logistic regression found that work level and direct employer significantly affect their classification. A multivariate analysis of variance of safety performance measures between the two groups indicated that the typical group had a significantly higher level of safety compliance than the atypical group, with no significant difference in safety participation or injury. The significance of this study lies in revealing the typical safety climate perception profile pattern of RMAA works and offering a new perspective of safety climate research.

  2. Exploring Typical and Atypical Safety Climate Perceptions of Practitioners in the Repair, Maintenance, Minor Alteration and Addition (RMAA) Sector in Hong Kong

    PubMed Central

    Hon, Carol K.H.; Liu, Yulin

    2016-01-01

    The safety of repair, maintenance, minor alteration and addition (RMAA) work is an under-explored area. This study explored the typical and atypical safety climate perceptions of practitioners in the RMAA sector in Hong Kong, based on a self-administered questionnaire survey of 662 local practitioners in the industry. Profile analysis, via multidimensional scaling of the respondents’ scores of three safety climate scales, identified one typical perception: high in management commitment to occupational health and safety (OHS) and employee involvement, low in applicability for safety rules and regulations, and low in responsibility for OHS. The respondents were clustered into typical and atypical perception groups according to their safety climate scores’ match to the typical perception. A comparison of demographics between the two groups with logistic regression found that work level and direct employer significantly affect their classification. A multivariate analysis of variance of safety performance measures between the two groups indicated that the typical group had a significantly higher level of safety compliance than the atypical group, with no significant difference in safety participation or injury. The significance of this study lies in revealing the typical safety climate perception profile pattern of RMAA works and offering a new perspective of safety climate research. PMID:27669269

  3. The effects and interactions of student, teacher, and setting variables on reading outcomes for kindergartners receiving supplemental reading intervention.

    PubMed

    Hagan-Burke, Shanna; Coyne, Michael D; Kwok, Oi-Man; Simmons, Deborah C; Kim, Minjung; Simmons, Leslie E; Skidmore, Susan T; Hernandez, Caitlin L; McSparran Ruby, Maureen

    2013-01-01

    This exploratory study examined the influences of student, teacher, and setting characteristics on kindergarteners' early reading outcomes and investigated whether those relations were moderated by type of intervention. Participants included 206 kindergarteners identified as at risk for reading difficulties and randomly assigned to one of two supplemental interventions: (a) an experimental explicit, systematic, code-based program or (b) their schools' typical kindergarten reading intervention. Results from separate multilevel structural equation models indicated that among student variables, entry-level alphabet knowledge was positively associated with phonemic and decoding outcomes in both conditions. Entry-level rapid automatized naming also positively influenced decoding outcomes in both conditions. However, its effect on phonemic outcomes was statistically significant only among children in the typical practice comparison condition. Regarding teacher variables, the quality of instruction was associated with significantly higher decoding outcomes in the typical reading intervention condition but had no statistically significant influence on phonemic outcomes in either condition. Among setting variables, instruction in smaller group sizes was associated with better phonemic outcomes in the comparison condition but had no statistically significant influence on outcomes of children in the intervention group. Mode of delivery (i.e., pullout vs. in class) had no statistically significant influence on either outcome variable.

  4. Preliminary evaluation of a commercially available videogame system as an adjunct therapeutic intervention for improving balance among children and adolescents with lower limb amputations.

    PubMed

    Andrysek, Jan; Klejman, Susan; Steinnagel, Bryan; Torres-Moreno, Ricardo; Zabjek, Karl F; Salbach, Nancy M; Moody, Kim

    2012-02-01

    To examine the safety, feasibility, and balance performance effects of a 4-week home-based balance therapy program using a commercially available videogame system. A pilot study involving a preintervention and postintervention design was conducted with measurements taken at baseline, immediately postintervention (week 5), and at follow-up (week 13) for retention. University hospital outpatient clinic and participants' places of residence. Children and adolescents with unilateral lower limb amputation (n=6; 3 transfemoral [TF] and 3 Van Ness) and age-matched, typically developing individuals (n=10) for baseline comparison. Two videogames involving weight shifting in standing were each played at home for 20 min/d, 4d/wk for a period of 4 weeks. A physical therapist provided initial instruction and monitoring. Postural control characteristics using center of pressure (COP) displacements during quiet standing; functional balance using the Community Balance and Mobility Scale (CB&M); and compliance, safety, and feasibility using custom questionnaires. Average playing times for the first 3 weeks ranged from 16.0 to 21.1 minutes for the 2 games. At baseline, the children and adolescents with TF amputation had substantially greater COP displacements than the Van Ness group and typically developing children and adolescents. Immediately postintervention, the COP displacements decreased in the TF amputees, resulting in values that were closer to those of the typically developing children. The average increase in CB&M score from baseline to follow-up was 6 points across participants. In-home, videogame-based balance training therapies can achieve excellent compliance in children and adolescents with lower limb amputation. With proper instructions and monitoring, the therapeutic intervention can be safely administered. Some improvements in postural control characteristics were seen in children and adolescents with balance deficits immediately postintervention, but long-term retention remains unclear. Copyright © 2012 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  5. Maternal Stress and Coping Strategies in Developmental Dyslexia: An Italian Multicenter Study.

    PubMed

    Carotenuto, Marco; Messina, Antonietta; Monda, Vincenzo; Precenzano, Francesco; Iacono, Diego; Verrotti, Alberto; Piccorossi, Alessandra; Gallai, Beatrice; Roccella, Michele; Parisi, Lucia; Maltese, Agata; Lavano, Francesco; Marotta, Rosa; Lavano, Serena Marianna; Lanzara, Valentina; Ferrentino, Roberta Ida; Pisano, Simone; Salerno, Margherita; Valenzano, Anna; Triggiani, Antonio Ivano; Polito, Anna N; Cibelli, Giuseppe; Monda, Marcellino; Messina, Giovanni; Ruberto, Maria; Esposito, Maria

    2017-01-01

    Studies about the impact of developmental dyslexia (DD) on parenting are scarce. Our investigation aimed to assess maternal stress levels and mothers' copying styles in a population of dyslexic children. A total of 874 children (500 boys, 374 girls; mean age 8.32 ± 2.33 years) affected by DD was included in the study. A total of 1,421 typically developing children (789 boys, 632 girls; mean age 8.25 ± 3.19 years) were recruited from local schools of participating Italian Regions (Abruzzo, Calabria, Campania, Puglia, Umbria, Sicily) and used as control-children group. All mothers (of both DD and typically developing children) filled out an evaluation for parental stress (Parenting Stress Index-Short Form) and coping strategies [Coping Inventory for Stressful Situations (CISS)]. No statistical differences for mean age ( p  = 0.456) and gender ( p  = 0.577) were found between DD and control children. Mothers of children affected by DD showed an higher rate of all parental stress indexes (Parental Distress domain p  < 0.001, Difficult Child p  < 0.001, Parent-Child Dysfunctional Interaction p  < 0.001, and Total Stress subscale score p  < 0.001) than controls mothers. According to the CISS evaluation, mothers of DD children reported a significantly higher rate of emotion-oriented ( p  < 0.001) and avoidance-oriented ( p  < 0.001) coping styles than mothers of typical developing children. On the other hand, a lower representation of task-oriented coping style was found in mothers of DD children ( p  < 0.001) in comparison to mothers of control-children. Our study shows the clinical relevance of the burden carried by the mothers of children affected by DD and suggests the importance to assess parents, particularly mothers, to improve family compliance and clinical management of this disorder.

  6. Lipreading Ability and Its Cognitive Correlates in Typically Developing Children and Children with Specific Language Impairment

    ERIC Educational Resources Information Center

    Heikkilä, Jenni; Lonka, Eila; Ahola, Sanna; Meronen, Auli; Tiippana, Kaisa

    2017-01-01

    Purpose: Lipreading and its cognitive correlates were studied in school-age children with typical language development and delayed language development due to specific language impairment (SLI). Method: Forty-two children with typical language development and 20 children with SLI were tested by using a word-level lipreading test and an extensive…

  7. Fine motor ability and psychiatric disorders in youth.

    PubMed

    Mendes, Lorenna Sena Teixeira; Manfro, Gisele Gus; Gadelha, Ary; Pan, Pedro Mario; Bressan, Rodrigo Affonseca; Rohde, Luis Augusto; Salum, Giovanni Abrahão

    2018-05-01

    Impaired fine motor ability has been linked to several domains of psychopathology. However, studies validating the specificity of this association among several categorical psychiatric disorders are still needed. The aim of this study was to assess differences in fine motor ability performance among four non-overlapping groups of psychiatric disorders and a group of typical developing comparisons (TDC). Our sample consisted of 2035 subjects aged 6-14-year-old. Diagnoses of psychiatric disorders were performed with the Development and Well-Being Assessment (DAWBA). Five non-overlapping groups without comorbidity were formed: phobic disorders (n = 101), distress disorders (n = 82), attention deficit hyperactivity disorder (ADHD) (n = 133), oppositional defiant disorder/conduct disorder (ODD/CD) (n = 52) and one group of typical developing comparisons (TDC) (n = 1667). Fine motor ability was evaluated by three tasks: sequential finger-thumb opposition, Oseretsky, and pronation/supination tests. Each task was assessed by total time to perform the movement and levels of accuracy, fluency, symmetry, precision, and coordination. We found that, when compared to TDC, the ADHD group performed more poorly in total fine motor ability (mean difference = - 0.28; p = 0.014), time to complete the task (mean difference = 0.36; p < 0.001), accuracy (mean difference = - 0.30; p = 0.005), fluency (mean difference = - 0.26; p = 0.03), symmetry (mean difference - 0.25; p = 0.04), precision (mean difference = - 0.26; p = 0.026), and coordination (mean difference = - 0.25; p = 0.042). The ADHD group also took more time to complete the task than the ODD/CD group (mean difference = 0.45; p = 0.037). No other significant between-group differences were found. Additional analyses showed those differences were statistically significant for all ADHD dimensions. Our results suggest that children with ADHD present impairments in all aspects of fine motor abilities compared to TDC, a difference not found in other psychiatric disorders.

  8. Theoretical and Empirical Comparisons between Two Models for Continuous Item Responses.

    ERIC Educational Resources Information Center

    Ferrando, Pere J.

    2002-01-01

    Analyzed the relations between two continuous response models intended for typical response items: the linear congeneric model and Samejima's continuous response model (CRM). Illustrated the relations described using an empirical example and assessed the relations through a simulation study. (SLD)

  9. Comparison of conventional and self-consolidating concrete for drilled shaft construction : [tech summary].

    DOT National Transportation Integrated Search

    2015-04-01

    Significant anomalies have been observed in many of the recent drilled shaft construction projects throughout Louisiana. : The anomalies typically occur in the form of honeycombing within the zones of heavy reinforcement or sometimes at the : shaft b...

  10. COMPARISON OF FATHEAD MINNOW AND HUMAN ESTROGEN RECEPTOR BINDING TO ENDOCRINE DISRUPTING COMPOUNDS

    EPA Science Inventory

    Environmental estrogens have the potential to disrupt endocrine function in a myriad of species. However, in vitro assays designed to detect and characterize endocrine disrupting chemicals (EDCs) typically utilize mammalian estrogen receptors. Our overall objective is to charac...

  11. Comparison of the use of notched wedge joints vs. traditional butt joints in Connecticut

    DOT National Transportation Integrated Search

    2008-11-07

    Performance of Hot Mix Asphalt (HMA) longitudinal joints have been an item of increasing scrutiny in : Connecticut. The traditional butt joint has typically been the method used in Connecticut. These joints : have been reportedly opening up, creating...

  12. Item Response Modeling of Forced-Choice Questionnaires

    ERIC Educational Resources Information Center

    Brown, Anna; Maydeu-Olivares, Alberto

    2011-01-01

    Multidimensional forced-choice formats can significantly reduce the impact of numerous response biases typically associated with rating scales. However, if scored with classical methodology, these questionnaires produce ipsative data, which lead to distorted scale relationships and make comparisons between individuals problematic. This research…

  13. Cross species comparisons of chemical interaction with recombinant steroid receptors in vitro.

    EPA Science Inventory

    Typically, mammalian receptors are used for in vitro hazard identification and screening for endocrine disrupting compounds. There is concern, however, that differences may exist in the affinities of environmental compounds for steroid receptors from other vertebrate classes. S...

  14. Subitizing and Counting in Typical and Atypical Development

    ERIC Educational Resources Information Center

    Schleifer, Patrick; Landerl, Karin

    2011-01-01

    Enumeration performance in standard dot counting paradigms was investigated for different age groups with typical and atypically poor development of arithmetic skills. Experiment 1 showed a high correspondence between response times and saccadic frequencies for four age groups with typical development. Age differences were more marked for the…

  15. Using Typical Infant Development to Inform Music Therapy with Children with Disabilities

    ERIC Educational Resources Information Center

    Wheeler, Barbara L.; Stultz, Sylvia

    2008-01-01

    This article illustrates some ways in which observations of typically-developing infants can inform music therapy and other work with children with disabilities. The research project that is described examines typical infant development with special attention to musical relatedness and communication. Videotapes of sessions centering on musical…

  16. Mother-Child Play: Children with Down Syndrome and Typical Development

    ERIC Educational Resources Information Center

    Venuti, P.; de Falco, S.; Esposito, G.; Bornstein, Marc H.

    2009-01-01

    Child solitary and collaborative mother-child play with 21 children with Down syndrome and 33 mental-age-matched typically developing children were compared. In solitary play, children with Down syndrome showed less exploratory but similar symbolic play compared to typically developing children. From solitary to collaborative play, children with…

  17. A Simplified Model of ARIS for Optimal Controller Design

    NASA Technical Reports Server (NTRS)

    Beech, Geoffrey S.; Hampton, R. David; Kross, Denny (Technical Monitor)

    2001-01-01

    Many space-science experiments require active vibration isolation. Boeing's Active Rack Isolation System (ARIS) isolates experiments at the rack (vs. experiment or sub-experiment) level, with multi e experiments per rack. An ARIS-isolated rack typically employs eight actuators and thirteen umbilicals; the umbilicals provide services such as power, data transmission, and cooling. Hampton, et al., used "Kane's method" to develop an analytical, nonlinear, rigid-body model of ARIS that includes full actuator dynamics (inertias). This model, less the umbilicals, was first implemented for simulation by Beech and Hampton; they developed and tested their model using two commercial-off-the-shelf (COTS) software packages. Rupert, et al., added umbilical-transmitted disturbances to this nonlinear model. Because the nonlinear model, even for the untethered system, is both exceedingly complex and "encapsulated" inside these COTS tools, it is largely inaccessible to ARIS controller designers. This paper shows that ISPR rattle-space constraints and small ARIS actuator masses permit considerable model simplification, without significant loss of fidelity. First, for various loading conditions, comparisons are made between the dynamic responses of the nonlinear model (untethered) and a truth model. Then comparisons are made among nonlinear, linearized, and linearized reduced-mass models. It is concluded that these three models all capture the significant system rigid-body dynamics, with the third being preferred due to its relative simplicity.

  18. Disorders of representation and control in semantic cognition: Effects of familiarity, typicality, and specificity

    PubMed Central

    Rogers, Timothy T.; Patterson, Karalyn; Jefferies, Elizabeth; Lambon Ralph, Matthew A.

    2015-01-01

    We present a case-series comparison of patients with cross-modal semantic impairments consequent on either (a) bilateral anterior temporal lobe atrophy in semantic dementia (SD) or (b) left-hemisphere fronto-parietal and/or posterior temporal stroke in semantic aphasia (SA). Both groups were assessed on a new test battery designed to measure how performance is influenced by concept familiarity, typicality and specificity. In line with previous findings, performance in SD was strongly modulated by all of these factors, with better performance for more familiar items (regardless of typicality), for more typical items (regardless of familiarity) and for tasks that did not require very specific classification, consistent with the gradual degradation of conceptual knowledge in SD. The SA group showed significant impairments on all tasks but their sensitivity to familiarity, typicality and specificity was more variable and governed by task-specific effects of these factors on controlled semantic processing. The results are discussed with reference to theories about the complementary roles of representation and manipulation of semantic knowledge. PMID:25934635

  19. Validation of AIRS Retrievals of CO2 via Comparison to In Situ Measurements

    NASA Technical Reports Server (NTRS)

    Olsen, Edward T.; Chahine, Moustafa T.; Chen, Luke L.; Jiang, Xun; Pagano, Thomas S.; Yung, Yuk L.

    2008-01-01

    Topics include AIRS on Aqua, 2002-present with discussion about continued operation to 2011 and beyond and background, including spectrum, weighting functions, and initialization; comparison with aircraft and FTIR measurements in Masueda (CONTRAIL) JAL flask measurements, Park Falls, WI FTIR, Bremen, GDF, and Spitsbergen, Norway; AIRS retrievals over addition FTIR sites in Darwin, AU and Lauder, NZ; and mid-tropospheric carbon dioxide weather and contribution from major surface sources. Slide titles include typical AIRS infrared spectrum, AIRS sensitivity for retrieving CO2 profiles, independence of CO2 solution with respect to the initial guess, available in situ measurements for validation and comparison, comparison of collocated V1.5x AIRS CO2 (N_coll greater than or equal to 9) with INTEX-NA and SPURT;

  20. Application of high-throughput mini-bioreactor system for systematic scale-down modeling, process characterization, and control strategy development.

    PubMed

    Janakiraman, Vijay; Kwiatkowski, Chris; Kshirsagar, Rashmi; Ryll, Thomas; Huang, Yao-Ming

    2015-01-01

    High-throughput systems and processes have typically been targeted for process development and optimization in the bioprocessing industry. For process characterization, bench scale bioreactors have been the system of choice. Due to the need for performing different process conditions for multiple process parameters, the process characterization studies typically span several months and are considered time and resource intensive. In this study, we have shown the application of a high-throughput mini-bioreactor system viz. the Advanced Microscale Bioreactor (ambr15(TM) ), to perform process characterization in less than a month and develop an input control strategy. As a pre-requisite to process characterization, a scale-down model was first developed in the ambr system (15 mL) using statistical multivariate analysis techniques that showed comparability with both manufacturing scale (15,000 L) and bench scale (5 L). Volumetric sparge rates were matched between ambr and manufacturing scale, and the ambr process matched the pCO2 profiles as well as several other process and product quality parameters. The scale-down model was used to perform the process characterization DoE study and product quality results were generated. Upon comparison with DoE data from the bench scale bioreactors, similar effects of process parameters on process yield and product quality were identified between the two systems. We used the ambr data for setting action limits for the critical controlled parameters (CCPs), which were comparable to those from bench scale bioreactor data. In other words, the current work shows that the ambr15(TM) system is capable of replacing the bench scale bioreactor system for routine process development and process characterization. © 2015 American Institute of Chemical Engineers.

  1. Resting-state fMRI data reflects default network activity rather than null data: A defense of commonly employed methods to correct for multiple comparisons.

    PubMed

    Slotnick, Scott D

    2017-07-01

    Analysis of functional magnetic resonance imaging (fMRI) data typically involves over one hundred thousand independent statistical tests; therefore, it is necessary to correct for multiple comparisons to control familywise error. In a recent paper, Eklund, Nichols, and Knutsson used resting-state fMRI data to evaluate commonly employed methods to correct for multiple comparisons and reported unacceptable rates of familywise error. Eklund et al.'s analysis was based on the assumption that resting-state fMRI data reflect null data; however, their 'null data' actually reflected default network activity that inflated familywise error. As such, Eklund et al.'s results provide no basis to question the validity of the thousands of published fMRI studies that have corrected for multiple comparisons or the commonly employed methods to correct for multiple comparisons.

  2. Visual Form Perception Can Be a Cognitive Correlate of Lower Level Math Categories for Teenagers.

    PubMed

    Cui, Jiaxin; Zhang, Yiyun; Cheng, Dazhi; Li, Dawei; Zhou, Xinlin

    2017-01-01

    Numerous studies have assessed the cognitive correlates of performance in mathematics, but little research has been conducted to systematically examine the relations between visual perception as the starting point of visuospatial processing and typical mathematical performance. In the current study, we recruited 223 seventh graders to perform a visual form perception task (figure matching), numerosity comparison, digit comparison, exact computation, approximate computation, and curriculum-based mathematical achievement tests. Results showed that, after controlling for gender, age, and five general cognitive processes (choice reaction time, visual tracing, mental rotation, spatial working memory, and non-verbal matrices reasoning), visual form perception had unique contributions to numerosity comparison, digit comparison, and exact computation, but had no significant relation with approximate computation or curriculum-based mathematical achievement. These results suggest that visual form perception is an important independent cognitive correlate of lower level math categories, including the approximate number system, digit comparison, and exact computation.

  3. Comparison of two stand-alone CADe systems at multiple operating points

    NASA Astrophysics Data System (ADS)

    Sahiner, Berkman; Chen, Weijie; Pezeshk, Aria; Petrick, Nicholas

    2015-03-01

    Computer-aided detection (CADe) systems are typically designed to work at a given operating point: The device displays a mark if and only if the level of suspiciousness of a region of interest is above a fixed threshold. To compare the standalone performances of two systems, one approach is to select the parameters of the systems to yield a target false-positive rate that defines the operating point, and to compare the sensitivities at that operating point. Increasingly, CADe developers offer multiple operating points, which necessitates the comparison of two CADe systems involving multiple comparisons. To control the Type I error, multiple-comparison correction is needed for keeping the family-wise error rate (FWER) less than a given alpha-level. The sensitivities of a single modality at different operating points are correlated. In addition, the sensitivities of the two modalities at the same or different operating points are also likely to be correlated. It has been shown in the literature that when test statistics are correlated, well-known methods for controlling the FWER are conservative. In this study, we compared the FWER and power of three methods, namely the Bonferroni, step-up, and adjusted step-up methods in comparing the sensitivities of two CADe systems at multiple operating points, where the adjusted step-up method uses the estimated correlations. Our results indicate that the adjusted step-up method has a substantial advantage over other the two methods both in terms of the FWER and power.

  4. Pattern recognition of satellite cloud imagery for improved weather prediction

    NASA Technical Reports Server (NTRS)

    Gautier, Catherine; Somerville, Richard C. J.; Volfson, Leonid B.

    1986-01-01

    The major accomplishment was the successful development of a method for extracting time derivative information from geostationary meteorological satellite imagery. This research is a proof-of-concept study which demonstrates the feasibility of using pattern recognition techniques and a statistical cloud classification method to estimate time rate of change of large-scale meteorological fields from remote sensing data. The cloud classification methodology is based on typical shape function analysis of parameter sets characterizing the cloud fields. The three specific technical objectives, all of which were successfully achieved, are as follows: develop and test a cloud classification technique based on pattern recognition methods, suitable for the analysis of visible and infrared geostationary satellite VISSR imagery; develop and test a methodology for intercomparing successive images using the cloud classification technique, so as to obtain estimates of the time rate of change of meteorological fields; and implement this technique in a testbed system incorporating an interactive graphics terminal to determine the feasibility of extracting time derivative information suitable for comparison with numerical weather prediction products.

  5. Early gross motor development of preterm infants according to the Alberta Infant Motor Scale.

    PubMed

    van Haastert, I C; de Vries, L S; Helders, P J M; Jongmans, M J

    2006-11-01

    To systematically examine gross motor development in the first 18 months of life of preterm infants. A total of 800 preterm infants (356 boys), ages between 1 and 18 months and corrected for degree of prematurity, were assessed with the use of the Alberta Infant Motor Scale. Comparison of the mean Alberta Infant Motor Scale scores of the preterm infants with the norm-referenced values derived from term infants revealed that as a group, the preterm infants scored significantly lower at all age levels, even with full correction for degree of prematurity. In general, preterm infants exhibit different gross motor developmental trajectories compared with term infants in the first 18 months of life. The gross motor developmental profile of preterm infants may reflect a variant of typical gross motor development, which seems most likely to be specific for this population. As a consequence, adjusted norms should be used for proper evaluation and clinical decision-making in relation to preterm infants.

  6. Adaptive Wiener filter super-resolution of color filter array images.

    PubMed

    Karch, Barry K; Hardie, Russell C

    2013-08-12

    Digital color cameras using a single detector array with a Bayer color filter array (CFA) require interpolation or demosaicing to estimate missing color information and provide full-color images. However, demosaicing does not specifically address fundamental undersampling and aliasing inherent in typical camera designs. Fast non-uniform interpolation based super-resolution (SR) is an attractive approach to reduce or eliminate aliasing and its relatively low computational load is amenable to real-time applications. The adaptive Wiener filter (AWF) SR algorithm was initially developed for grayscale imaging and has not previously been applied to color SR demosaicing. Here, we develop a novel fast SR method for CFA cameras that is based on the AWF SR algorithm and uses global channel-to-channel statistical models. We apply this new method as a stand-alone algorithm and also as an initialization image for a variational SR algorithm. This paper presents the theoretical development of the color AWF SR approach and applies it in performance comparisons to other SR techniques for both simulated and real data.

  7. Assessing False-Belief Understanding in Children with Autism Using a Computer Application: A Pilot Study.

    PubMed

    Carlsson, Emilia; Miniscalco, Carmela; Gillberg, Christopher; Åsberg Johnels, Jakob

    2018-03-26

    We have developed a False-Belief (FB) understanding task for use on a computer tablet, trying to assess FB understanding in a less social way. It is based on classical FB protocols, and additionally includes a manipulation of language in an attempt to explore the facilitating effect of linguistic support during FB processing. Specifically, the FB task was presented in three auditory conditions: narrative, silent, and interference. The task was assumed to shed new light on the FB difficulties often observed in Autism Spectrum Disorder (ASD). Sixty-eight children with ASD (M = 7.5 years) and an age matched comparison group with 98 typically developing (TD) children were assessed with the FB task. The children with ASD did not perform above chance level in any condition, and significant differences in success rates were found between the groups in two conditions (silent and narrative), with TD children performing better. We discuss implications, limitations, and further developments.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Habte, A.; Lopez, A.; Sengupta, M.

    Typical Meteorological Year (TMY) data sets provide industry standard resource information for building designers and are commonly used by the solar industry to estimate photovoltaic and concentrating solar power system performance. Historically, TMY data sets were only available for certain station locations, but current TMY data sets are available on the same grid as the National Solar Radiation Database data and are referred to as the gridded TMY. In this report, a comparison of TMY, typical direct (normal irradiance) year (TDY), and typical global (horizontal irradiance) year (TGY) data sets were performed to better understand the impact of ancillary weathermore » variables upon them. These analyses identified geographical areas of high and low temporal and spatial variability, thereby providing insight into the representativeness of a particular TMY data set for use in renewable energy as well as other applications.« less

  9. Promoting balance and jumping skills in children with Down syndrome.

    PubMed

    Wang, Wai-Yi; Ju, Yun-Huei

    2002-04-01

    The purpose of this study was to investigate the changes in balance and qualitative and quantitative jumping performances by 20 children with Down syndrome (3 to 6 years) on jumping lessons. 30 typical children ages 3 to 6 years were recruited as a comparison group. Before the jumping lesson, a pretest was given subjects for balance and jumping skill measures based on the Motor Proficiency and Motor Skill Inventory, respectively. Subjects with Down syndrome received 3 sessions on jumping per week for 6 weeks but not the typical children. Then, a posttest was administered to all subjects. Analysis of covariance showed the pre- and posttest differences on scores for floor walk, beam walk, and horizontal and vertical jumping by subjects with Down syndrome were significantly greater than those for the typical children.

  10. The neural correlates of internal and external comparisons: an fMRI study.

    PubMed

    Wen, Xue; Xiang, Yanhui; Cant, Jonathan S; Wang, Tingting; Cupchik, Gerald; Huang, Ruiwang; Mo, Lei

    2017-01-01

    Many previous studies have suggested that various comparisons rely on the same cognitive and neural mechanisms. However, little attention has been paid to exploring the commonalities and differences between the internal comparison based on concepts or rules and the external comparison based on perception. In the present experiment, moral beauty comparison and facial beauty comparison were selected as the representatives of internal comparison and external comparison, respectively. Functional magnetic resonance imaging (fMRI) was used to record brain activity while participants compared the level of moral beauty of two scene drawings containing moral acts or the level of facial beauty of two face photos. In addition, a physical size comparison task with the same stimuli as the beauty comparison was included. We observed that both the internal moral beauty comparison and external facial beauty comparison obeyed a typical distance effect and this behavioral effect recruited a common frontoparietal network involved in comparisons of simple physical magnitudes such as size. In addition, compared to external facial beauty comparison, internal moral beauty comparison induced greater activity in more advanced and complex cortical regions, such as the bilateral middle temporal gyrus and middle occipital gyrus, but weaker activity in the putamen, a subcortical region. Our results provide novel neural evidence for the comparative process and suggest that different comparisons may rely on both common cognitive processes as well as distinct and specific cognitive components.

  11. Using developmental cognitive neuroscience to study behavioral and attentional control.

    PubMed

    Astle, Duncan E; Scerif, Gaia

    2009-03-01

    Adult cognitive neuroscience employs a wide variety of techniques to investigate a broad range of behavioral and cognitive functions. One prominent area of study is that of executive control, complemented by a smaller but growing literature exploring the developmental cognitive neuroscience of executive control. To date this approach has often compared children with specific developmental disorders, such as ADHD and ASD, with typically developing controls. Whilst these comparisons have done much to advance our understanding of the neural markers that underpin behavioral difficulties at specific time-points in development, we contend that they should leave developmental cognitive neuroscientists wanting. Studying the neural correlates of typical changes in executive control in their own right can reveal how different neural mechanisms characteristic of the adult end-state emerge, and it can therefore inform the adult cognitive neuroscience of executive control itself. The current review addresses the extent to which developmentalists and adult cognitive neuroscientists have tapped this common ground. Some very elegant investigations illustrate how seemingly common processes in adulthood present as separable in childhood, on the basis of their distinctive developmental trajectories. These demonstrations have implications not only for an understanding of changing behavior from infancy through childhood and adolescence into adulthood, but, moreover, for our grasp of the adult end-state per se. We contend that, if used appropriately, developmental cognitive neuroscience could enable us to construct a more mechanistic account of executive control.

  12. Parent-child agreement on the Behavior Rating Inventory of Executive Functioning (BRIEF) in a community sample of adolescents.

    PubMed

    Egan, Kaitlyn N; Cohen, L Adelyn; Limbers, Christine

    2018-03-06

    Despite its widespread use, a minimal amount is known regarding the agreement between parent and youth ratings of youth's executive functioning on the Behavior Rating Inventory of Executive Functioning (BRIEF) in typically developing youth. The present study examined parent-child agreement on the BRIEF with a community sample of adolescents and their parents. Ninety-seven parent-child dyads (M age  = 13.91 years; SD = .52) completed the BRIEF self- and parent-report forms and a demographic questionnaire. Intraclass Correlation Coefficients (ICCs) and paired sample t-tests were used to evaluate agreement between self- and parent-reports on the BRIEF. Total sample ICCs indicated moderate to good parent-child agreement (0.46-0.68). Parents from the total sample reported significantly higher mean T-scores for their adolescents on Inhibit, Working Memory, Planning/Organization, Behavioral Regulation Index (BRI), Metacognition Index, and Global Executive Composite. Differences were found in regard to gender and race/ethnicity: ICCs were higher between parent-girl dyads on the scales that comprise the BRI than between parent-boy dyads. Parent-adolescent ICCs were also higher for adolescents who self-identified as White in comparison to those who identified as Non-White/Mixed Race on Emotional Control. These findings suggest gender and racial/ethnic differences should be considered when examining parent-child agreement on the BRIEF in typically developing adolescents.

  13. The Use of AC-DC-AC Methods in Assessing Corrosion Resistance Performance of Coating Systems for Magnesium Alloys

    NASA Astrophysics Data System (ADS)

    McCune, Robert C.; Upadhyay, Vinod; Wang, Yar-Ming; Battocchi, Dante

    The potential utility of AC-DC-AC electrochemical methods in comparative measures of corrosion-resisting coating system performance for magnesium alloys under consideration for the USAMP "Magnesium Front End Research and Development" project was previously shown in this forum [1]. Additional studies of this approach using statistically-designed experiments have been conducted with focus on alloy types, pretreatment, topcoat material and topcoat thickness as the variables. Additionally, sample coupons made for these designed experiments were also subjected to a typical automotive cyclic corrosion test cycle (SAE J2334) as well as ASTM B117 for comparison of relative performance. Results of these studies are presented along with advantages and limitations of the proposed methodology.

  14. An Overview of Recent Developments in Computational Aeroelasticity

    NASA Technical Reports Server (NTRS)

    Bennett, Robert M.; Edwards, John W.

    2004-01-01

    The motivation for Computational Aeroelasticity (CA) and the elements of one type of the analysis or simulation process are briefly reviewed. The need for streamlining and improving the overall process to reduce elapsed time and improve overall accuracy is discussed. Further effort is needed to establish the credibility of the methodology, obtain experience, and to incorporate the experience base to simplify the method for future use. Experience with the application of a variety of Computational Aeroelasticity programs is summarized for the transonic flutter of two wings, the AGARD 445.6 wing and a typical business jet wing. There is a compelling need for a broad range of additional flutter test cases for further comparisons. Some existing data sets that may offer CA challenges are presented.

  15. Dynamic simulation of a reverse Brayton refrigerator

    NASA Astrophysics Data System (ADS)

    Peng, N.; Lei, L. L.; Xiong, L. Y.; Tang, J. C.; Dong, B.; Liu, L. Q.

    2014-01-01

    A test refrigerator based on the modified Reverse Brayton cycle has been developed in the Chinese Academy of Sciences recently. To study the behaviors of this test refrigerator, a dynamic simulation has been carried out. The numerical model comprises the typical components of the test refrigerator: compressor, valves, heat exchangers, expander and heater. This simulator is based on the oriented-object approach and each component is represented by a set of differential and algebraic equations. The control system of the test refrigerator is also simulated, which can be used to optimize the control strategies. This paper describes all the models and shows the simulation results. Comparisons between simulation results and experimental data are also presented. Experimental validation on the test refrigerator gives satisfactory results.

  16. Comparative Bacterial Proteomics: Analysis of the Core Genome Concept

    PubMed Central

    Callister, Stephen J.; McCue, Lee Ann; Turse, Joshua E.; Monroe, Matthew E.; Auberry, Kenneth J.; Smith, Richard D.; Adkins, Joshua N.; Lipton, Mary S.

    2008-01-01

    While comparative bacterial genomic studies commonly predict a set of genes indicative of common ancestry, experimental validation of the existence of this core genome requires extensive measurement and is typically not undertaken. Enabled by an extensive proteome database developed over six years, we have experimentally verified the expression of proteins predicted from genomic ortholog comparisons among 17 environmental and pathogenic bacteria. More exclusive relationships were observed among the expressed protein content of phenotypically related bacteria, which is indicative of the specific lifestyles associated with these organisms. Although genomic studies can establish relative orthologous relationships among a set of bacteria and propose a set of ancestral genes, our proteomics study establishes expressed lifestyle differences among conserved genes and proposes a set of expressed ancestral traits. PMID:18253490

  17. Repetitive behaviour in children with high functioning autism and obsessive compulsive disorder.

    PubMed

    Zandt, Fiona; Prior, Margot; Kyrios, Michael

    2007-02-01

    Children with Autism Spectrum Disorders (ASD) and children with Obsessive Compulsive Disorder (OCD) were compared on a range of repetitive behaviours. Parents reported similar levels of sameness behaviour and repetitive movements in the clinical groups, although children with OCD engaged in more repetitive behaviour focussed around routines and rituals. Children with OCD reported more compulsions and obsessions than children with ASD; both groups reported more compulsions and obsessions than a typically developing comparison group. Types of compulsions and obsessions tended to be less sophisticated in children with ASD than those with OCD. Sameness behaviour was more prevalent in younger children with OCD, but for children with ASD, age was not significantly related to sameness behaviour, repetitive movements, compulsions, or obsessions.

  18. The development of multitasking in children aged 7-12years: Evidence from cross-sectional and longitudinal data.

    PubMed

    Yang, Tian-Xiao; Xie, Weizhen; Chen, Chu-Sheng; Altgassen, Mareike; Wang, Ya; Cheung, Eric F C; Chan, Raymond C K

    2017-09-01

    This study investigated the development of multitasking ability across childhood. A sample of 65 typically developing children aged 7, 9, and 11years completed two multitasking tests across three time points within a year. Cross-sectional and longitudinal data consistently indicated continuous linear growth in children's multitasking ability. By the age of 12years, children could effectively perform a simple multitasking scenario comprising six equally important tasks, although their ability to strategically organize assorted tasks with varied values and priorities in a complex multitasking setting had not reached proficiency yet. Cognitive functions underlying a complex multitasking scenario varied in their developmental trajectories. Retrospective memory developed continuously from 7 to 12years of age, suggesting its supporting role in the development of multitasking. Planning skills developed slowly and showed practice effects for older children but not for younger children. The ability to adhere to plans also developed slowly, and children of all age groups benefited from practice. This study offers a preliminary benchmark for future comparison with clinical populations and may help to inform the development of targeted interventions. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Typical and Atypical Development of Basic Numerical Skills in Elementary School

    ERIC Educational Resources Information Center

    Landerl, Karin; Kolle, Christina

    2009-01-01

    Deficits in basic numerical processing have been identified as a central and potentially causal problem in developmental dyscalculia; however, so far not much is known about the typical and atypical development of such skills. This study assessed basic number skills cross-sectionally in 262 typically developing and 51 dyscalculic children in…

  20. Comparison of Bacteria and Color Removal in Two Surface Waters using Nanofiltration

    EPA Science Inventory

    Small communities typically have small budgets, but big issues to deal with in providing safe drinking water and protecting public health. Communities in remote locations are frequently faced with elevated levels of naturally-occurring organic matter (NOM) that combine with chlo...

  1. Comparison of Bacteria and Color Removal in Two Surface Waters using Nanofiltration

    EPA Science Inventory

    Small communities typically have small budgets, but big issues to deal with in providing safe drinking water and protecting public health. Communities in remote locations are frequently faced with elevated levels of naturally-occurring organic matter (NOM) that combine with chlor...

  2. Competitive binding comparison of endocrine-disrupting compounds to recombinant androgen receptor from fathead minnow, rainbow trout, and human

    EPA Science Inventory

    Typically, in vitro hazard assessments for the identification of endocrine-disrupting compounds (EDCs), including those outlined in the Endocrine Disruptor Screening and Testing Advisory Committee (EDSTAC) Tier 1 Screening protocols, utilize mammalian receptors. Evidence, however...

  3. Cover crop water quality benefits in intensive production

    USDA-ARS?s Scientific Manuscript database

    Fresh market tomatoes are typically grown in in raised beds covered in polyethylene mulch with bare-soil furrows between the beds. Field experiments were conducted over five years to examine two alternative management strategies. In side-by-side comparison with the traditional management practice, t...

  4. Emotional Abilities in Children with Oppositional Defiant Disorder (ODD): Impairments in Perspective-Taking and Understanding Mixed Emotions are Associated with High Callous-Unemotional Traits.

    PubMed

    O'Kearney, Richard; Salmon, Karen; Liwag, Maria; Fortune, Clare-Ann; Dawel, Amy

    2017-04-01

    Most studies of emotion abilities in disruptive children focus on emotion expression recognition. This study compared 74 children aged 4-8 years with ODD to 45 comparison children (33 healthy; 12 with an anxiety disorder) on behaviourally assessed measures of emotion perception, emotion perspective-taking, knowledge of emotions causes and understanding ambivalent emotions and on parent-reported cognitive and affective empathy. Adjusting for child's sex, age and expressive language ODD children showed a paucity in attributing causes to emotions but no other deficits relative to the comparison groups. ODD boys with high levels of callous-unemotional traits (CU) (n = 22) showed deficits relative to low CU ODD boys (n = 25) in emotion perspective-taking and in understanding ambivalent emotions. Low CU ODD boys did not differ from the healthy typically developing boys (n = 12). Impairments in emotion perceptive-taking and understanding mixed emotions in ODD boys are associated with the presence of a high level of CU.

  5. A comparison of response rates in the English Longitudinal Study of Ageing and the Health and Retirement Study

    PubMed Central

    Cheshire, Hayley; Ofstedal, Mary Beth; Scholes, Shaun; Schroeder, Mathis

    2013-01-01

    Survey response rates are an important measure of the quality of a survey; this is true for both longitudinal and cross-sectional surveys. However, the concept of a response rate in the context of a panel survey is more complex than is the case for a cross-sectional survey. There are typically many different response rates that can be calculated for a panel survey, each of which may be relevant for a specific purpose. The main objective of our paper is to document and compare response rates for two long-term panel studies of ageing, the English Longitudinal Study of Ageing (ELSA) and the Health and Retirement Study (HRS) in the United States. To guide our selection and calculation of response rates for the two studies, we use a framework that was developed by Peter Lynn (2005) and present several different types of longitudinal response rates for the two surveys. We discuss similarities and differences in the study designs and protocols and how some of the differences affect comparisons of response rates across the two studies. PMID:24432049

  6. Performance comparison of AV1, HEVC, and JVET video codecs on 360 (spherical) video

    NASA Astrophysics Data System (ADS)

    Topiwala, Pankaj; Dai, Wei; Krishnan, Madhu; Abbas, Adeel; Doshi, Sandeep; Newman, David

    2017-09-01

    This paper compares the coding efficiency performance on 360 videos, of three software codecs: (a) AV1 video codec from the Alliance for Open Media (AOM); (b) the HEVC Reference Software HM; and (c) the JVET JEM Reference SW. Note that 360 video is especially challenging content, in that one codes full res globally, but typically looks locally (in a viewport), which magnifies errors. These are tested in two different projection formats ERP and RSP, to check consistency. Performance is tabulated for 1-pass encoding on two fronts: (1) objective performance based on end-to-end (E2E) metrics such as SPSNR-NN, and WS-PSNR, currently developed in the JVET committee; and (2) informal subjective assessment of static viewports. Constant quality encoding is performed with all the three codecs for an unbiased comparison of the core coding tools. Our general conclusion is that under constant quality coding, AV1 underperforms HEVC, which underperforms JVET. We also test with rate control, where AV1 currently underperforms the open source X265 HEVC codec. Objective and visual evidence is provided.

  7. Analysis of He I 1083 nm Imaging Spectroscopy Using a Spectral Standard

    NASA Technical Reports Server (NTRS)

    Malanushenko, Elena V.; Jones, Harrison P.

    2004-01-01

    We develop a technique. for the analysis of He I 1083 nanometer spectra which addresses several difficulties through determination of a continuum background by comparison with a well calibrated standard and through removal of nearby solar and telluric blends by differential comparison to an average spectrum. The method is compared with earlier analysis of imaging spectroscopy obtained at the National Solar Observatory/Kitt Peak Vacuum Telescope (NSO/KPVT) with the NASA/NSO Spectromagnetograph (SPM). We examine distributions of Doppler velocity and line width as a function of central intensity for an active region, filament, quiet Sun, and coronal hole. For our example, we find that line widths and central intensity are oppositely correlated in a coronal hole and quiet Sun. Line widths are comparable to the quiet sun in the active region, are systematically lower in the filament, and extend to higher values in the coronal hole. Outward velocities of approximately equal to 2 to 4 kilometers per second are typically observed in the coronal hole. The sensitivity of these results to analysis technique is discussed.

  8. White sucker (Catostomus commersoni) growth and sexual maturation in pulp mill-contaminated and reference rivers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gagnon, M.M.; Bussieres, D.; Dodson, J.J.

    1995-02-01

    Induction of hepatic ethoxyresorufin-O-deethylase (EROD) activity and accumulation of chlorophenolic compounds typical of bleached-kraft mill effluent (BKME) in fish sampled downstream of a pulp mill on the St. Maurice River, Quebec, Canada, provided evidence of chemical exposure to BKME. In comparison, fish sampled over the same distances and in similar habitats in a noncontaminated reference river, the Gatineau River, demonstrated low EROD activity and contamination levels. Accelerated growth of white suckers occurred between 2 and 10 years of age in both rivers at downstream stations relative to upstream stations, suggesting the existence of gradients of nutrient enrichment independent of BKMEmore » contamination. The impact of BKME exposure was expressed as reduced investment in reproduction, as revealed by greater length at maturity, reduced gonad size, and more variable fecundity. These effects were not obvious in simple upstream-downstream comparisons, but became evident when fish from the uncontaminated Gatineau River showed increased gonadal development and reduced age and size at maturity in response to enhanced growth rates.« less

  9. Taking Halo-Independent Dark Matter Methods Out of the Bin

    DOE PAGES

    Fox, Patrick J.; Kahn, Yonatan; McCullough, Matthew

    2014-10-30

    We develop a new halo-independent strategy for analyzing emerging DM hints, utilizing the method of extended maximum likelihood. This approach does not require the binning of events, making it uniquely suited to the analysis of emerging DM direct detection hints. It determines a preferred envelope, at a given confidence level, for the DM velocity integral which best fits the data using all available information and can be used even in the case of a single anomalous scattering event. All of the halo-independent information from a direct detection result may then be presented in a single plot, allowing simple comparisons betweenmore » multiple experiments. This results in the halo-independent analogue of the usual mass and cross-section plots found in typical direct detection analyses, where limit curves may be compared with best-fit regions in halo-space. The method is straightforward to implement, using already-established techniques, and its utility is demonstrated through the first unbinned halo-independent comparison of the three anomalous events observed in the CDMS-Si detector with recent limits from the LUX experiment.« less

  10. Mass comparisons of electric propulsion systems for NSSK of geosynchronous spacecraft

    NASA Technical Reports Server (NTRS)

    Rawlin, Vincent K.; Majcher, Gregory A.

    1991-01-01

    A model was developed and exercised to allow wet mass comparisons of three axis stabilized communication satellites delivered to geosynchronous transfer orbit. The mass benefits of using advanced chemical propulsion for apogee injection and north-south stationkeeping (NSSK) functions or electric propulsion (hydrazine arcjets and xenon ion thrusters) for NSSK functions are documented. A large derated ion thrusters is proposed which minimizes thruster lifetime concerns and qualification test times when compared to those of smaller ion thrusters planned for NSSK applications. The mass benefits, which depend on the spacecraft mass and mission duration, increase dramatically with arcjet specific impulse in the 500 to 600 s range, but are nearly constant for the derated ion thruster operated in the 2300 to 3000 s range. For a given mission, the mass benefits with an ion system are typically double those of the arcjet system; however, the total thrusting time with arcjets is less than 1/3 that with ion thrusters for the same thruster power. The mass benefits may permit increases in revenue producing payload or reduce launch costs by allowing a move to a smaller launch vehicle.

  11. Quantitative comparison of alternative methods for coarse-graining biological networks

    PubMed Central

    Bowman, Gregory R.; Meng, Luming; Huang, Xuhui

    2013-01-01

    Markov models and master equations are a powerful means of modeling dynamic processes like protein conformational changes. However, these models are often difficult to understand because of the enormous number of components and connections between them. Therefore, a variety of methods have been developed to facilitate understanding by coarse-graining these complex models. Here, we employ Bayesian model comparison to determine which of these coarse-graining methods provides the models that are most faithful to the original set of states. We find that the Bayesian agglomerative clustering engine and the hierarchical Nyström expansion graph (HNEG) typically provide the best performance. Surprisingly, the original Perron cluster cluster analysis (PCCA) method often provides the next best results, outperforming the newer PCCA+ method and the most probable paths algorithm. We also show that the differences between the models are qualitatively significant, rather than being minor shifts in the boundaries between states. The performance of the methods correlates well with the entropy of the resulting coarse-grainings, suggesting that finding states with more similar populations (i.e., avoiding low population states that may just be noise) gives better results. PMID:24089717

  12. 1996 PAMS hydrocarbon QA studies in EPA Region II: Part II. Trends and insights

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Teitz, A.; Kantz, M.

    1997-12-31

    Comparison of ambient air samples between EPA Region II and the PAMS monitoring organizations within the Region, and comparisons among EPA Regions I, II, and III, revealed the following analytical trends: (1) Agreement between laboratories was typically between 10-20% for many of the PAMS analytes found at higher concentrations, i.e., butane, isopentane, benzene, toluene, and m/p-xylene; (2) Nafion dryer systems tended to underestimate the amount of acetylene by 35-50%; (3) Isobutylene co-elution with 1-butene proved difficult to resolve unless a 100 meter DB-1 or a regular length PLOT GC column was used; (4) Organizations that monitor for polar compounds foundmore » that co-elution of ethanol/acetone can interfere with the analysis of 1-pentene; (5) Analytical systems capable of polar analyses can have co-elution and/or misidentification of these aldehydes, typically in the styrene/heptanal/o-xylene regions of the chromatogram; and (6) Tetrachloroethylene was found to interfere with octane quantitation in some analyses.« less

  13. An empirical evaluation of software quality assurance practices and challenges in a developing country: a comparison of Nigeria and Turkey.

    PubMed

    Sowunmi, Olaperi Yeside; Misra, Sanjay; Fernandez-Sanz, Luis; Crawford, Broderick; Soto, Ricardo

    2016-01-01

    The importance of quality assurance in the software development process cannot be overemphasized because its adoption results in high reliability and easy maintenance of the software system and other software products. Software quality assurance includes different activities such as quality control, quality management, quality standards, quality planning, process standardization and improvement amongst others. The aim of this work is to further investigate the software quality assurance practices of practitioners in Nigeria. While our previous work covered areas on quality planning, adherence to standardized processes and the inherent challenges, this work has been extended to include quality control, software process improvement and international quality standard organization membership. It also makes comparison based on a similar study carried out in Turkey. The goal is to generate more robust findings that can properly support decision making by the software community. The qualitative research approach, specifically, the use of questionnaire research instruments was applied to acquire data from software practitioners. In addition to the previous results, it was observed that quality assurance practices are quite neglected and this can be the cause of low patronage. Moreover, software practitioners are neither aware of international standards organizations or the required process improvement techniques; as such their claimed standards are not aligned to those of accredited bodies, and are only limited to their local experience and knowledge, which makes it questionable. The comparison with Turkey also yielded similar findings, making the results typical of developing countries. The research instrument used was tested for internal consistency using the Cronbach's alpha, and it was proved reliable. For the software industry in developing countries to grow strong and be a viable source of external revenue, software assurance practices have to be taken seriously because its effect is evident in the final product. Moreover, quality frameworks and tools which require minimum time and cost are highly needed in these countries.

  14. Visible Social Interactions Do Not Support the Development of False Belief Understanding in the Absence of Linguistic Input: Evidence from Deaf Adult Homesigners.

    PubMed

    Gagne, Deanna L; Coppola, Marie

    2017-01-01

    Congenitally deaf individuals exhibit enhanced visuospatial abilities relative to normally hearing individuals. An early example is the increased sensitivity of deaf signers to stimuli in the visual periphery (Neville and Lawson, 1987a). While these enhancements are robust and extend across a number of visual and spatial skills, they seem not to extend to other domains which could potentially build on these enhancements. For example, congenitally deaf children, in the absence of adequate language exposure and acquisition, do not develop typical social cognition skills as measured by traditional Theory of Mind tasks. These delays/deficits occur despite their presumed lifetime use of visuo-perceptual abilities to infer the intentions and behaviors of others (e.g., Pyers and Senghas, 2009; O'Reilly et al., 2014). In a series of studies, we explore the limits on the plasticity of visually based socio-cognitive abilities, from perspective taking to Theory of Mind/False Belief, in rarely studied individuals: deaf adults who have not acquired a conventional language (Homesigners). We compared Homesigners' performance to that of two other understudied groups in the same culture: Deaf signers of an emerging language (Cohort 1 of Nicaraguan Sign Language), and hearing speakers of Spanish with minimal schooling. We found that homesigners performed equivalently to both comparison groups with respect to several visual socio-cognitive abilities: Perspective Taking (Levels 1 and 2), adapted from Masangkay et al. (1974), and the False Photograph task, adapted from Leslie and Thaiss (1992). However, a lifetime of visuo-perceptual experiences (observing the behavior and interactions of others) did not support success on False Belief tasks, even when linguistic demands were minimized. Participants in the comparison groups outperformed the Homesigners, but did not universally pass the False Belief tasks. Our results suggest that while some of the social development achievements of young typically developing children may be dissociable from their linguistic experiences, language and/or educational experiences clearly scaffolds the transition into False Belief understanding. The lack of experience using a shared language cannot be overcome, even with the benefit of many years of observing others' behaviors and the potential neural reorganization and visuospatial enhancements resulting from deafness.

  15. Visible Social Interactions Do Not Support the Development of False Belief Understanding in the Absence of Linguistic Input: Evidence from Deaf Adult Homesigners

    PubMed Central

    Gagne, Deanna L.; Coppola, Marie

    2017-01-01

    Congenitally deaf individuals exhibit enhanced visuospatial abilities relative to normally hearing individuals. An early example is the increased sensitivity of deaf signers to stimuli in the visual periphery (Neville and Lawson, 1987a). While these enhancements are robust and extend across a number of visual and spatial skills, they seem not to extend to other domains which could potentially build on these enhancements. For example, congenitally deaf children, in the absence of adequate language exposure and acquisition, do not develop typical social cognition skills as measured by traditional Theory of Mind tasks. These delays/deficits occur despite their presumed lifetime use of visuo-perceptual abilities to infer the intentions and behaviors of others (e.g., Pyers and Senghas, 2009; O’Reilly et al., 2014). In a series of studies, we explore the limits on the plasticity of visually based socio-cognitive abilities, from perspective taking to Theory of Mind/False Belief, in rarely studied individuals: deaf adults who have not acquired a conventional language (Homesigners). We compared Homesigners’ performance to that of two other understudied groups in the same culture: Deaf signers of an emerging language (Cohort 1 of Nicaraguan Sign Language), and hearing speakers of Spanish with minimal schooling. We found that homesigners performed equivalently to both comparison groups with respect to several visual socio-cognitive abilities: Perspective Taking (Levels 1 and 2), adapted from Masangkay et al. (1974), and the False Photograph task, adapted from Leslie and Thaiss (1992). However, a lifetime of visuo-perceptual experiences (observing the behavior and interactions of others) did not support success on False Belief tasks, even when linguistic demands were minimized. Participants in the comparison groups outperformed the Homesigners, but did not universally pass the False Belief tasks. Our results suggest that while some of the social development achievements of young typically developing children may be dissociable from their linguistic experiences, language and/or educational experiences clearly scaffolds the transition into False Belief understanding. The lack of experience using a shared language cannot be overcome, even with the benefit of many years of observing others’ behaviors and the potential neural reorganization and visuospatial enhancements resulting from deafness. PMID:28626432

  16. Development of a 5-Component Balance for Water Tunnel Applications

    NASA Technical Reports Server (NTRS)

    Suarez, Carlos J.; Kramer, Brian R.; Smith, Brooke C.

    1999-01-01

    The principal objective of this research/development effort was to develop a multi-component strain gage balance to measure both static and dynamic forces and moments on models tested in flow visualization water tunnels. A balance was designed that allows measuring normal and side forces, and pitching, yawing and rolling moments (no axial force). The balance mounts internally in the model and is used in a manner typical of wind tunnel balances. The key differences between a water tunnel balance and a wind tunnel balance are the requirement for very high sensitivity since the loads are very low (typical normal force is 90 grams or 0.2 lbs), the need for water proofing the gage elements, and the small size required to fit into typical water tunnel models. The five-component balance was calibrated and demonstrated linearity in the responses of the primary components to applied loads, very low interactions between the sections and no hysteresis. Static experiments were conducted in the Eidetics water tunnel with delta wings and F/A-18 models. The data were compared to forces and moments from wind tunnel tests of the same or similar configurations. The comparison showed very good agreement, providing confidence that loads can be measured accurately in the water tunnel with a relatively simple multi-component internal balance. The success of the static experiments encouraged the use of the balance for dynamic experiments. Among the advantages of conducting dynamic tests in a water tunnel are less demanding motion and data acquisition rates than in a wind tunnel test (because of the low-speed flow) and the capability of performing flow visualization and force/moment (F/M) measurements simultaneously with relative simplicity. This capability of simultaneous flow visualization and for F/M measurements proved extremely useful to explain the results obtained during these dynamic tests. In general, the development of this balance should encourage the use of water tunnels for a wider range of quantitative and qualitative experiments, especially during the preliminary phase of aircraft design.

  17. Passive in-situ chemical sensor

    DOEpatents

    Morrell, Jonathan S [Farragut, TN; Ripley, Edward B [Knoxville, TN

    2012-02-14

    A chemical sensor for assessing a chemical of interest. In typical embodiments the chemical sensor includes a first thermocouple and second thermocouple. A reactive component is typically disposed proximal to the second thermal couple, and is selected to react with the chemical of interest and generate a temperature variation that may be detected by a comparison of a temperature sensed by the second thermocouple compared with a concurrent temperature detected by the first thermocouple. Further disclosed is a method for assessing a chemical of interest and a method for identifying a reaction temperature for a chemical of interest in a system.

  18. Is the liquid or the solid phase responsible for the low melting points of ionic liquids? Alkyl-chain-length dependence of thermodynamic properties of [C nmim][Tf 2N

    NASA Astrophysics Data System (ADS)

    Shimizu, Yoshitaka; Ohte, Yoko; Yamamura, Yasuhisa; Saito, Kazuya

    2009-03-01

    To establish the alkyl-chain-length dependences of thermodynamic properties of typical ionic liquids [C nmim][Tf 2N], the heat capacities of compounds with n = 2 and 18 were measured by adiabatic calorimetry. The comparison with other ionic liquids and typical molecular substances reveals that the low melting point of [C nmim][Tf 2N] with a short alkyl chain mainly originate in the large fusion entropy arising from the low entropy of the crystalline phase.

  19. Analysis and comparison of wrist splint designs using the finite element method: Multi-material three-dimensional printing compared to typical existing practice with thermoplastics.

    PubMed

    Cazon, Aitor; Kelly, Sarah; Paterson, Abby M; Bibb, Richard J; Campbell, R Ian

    2017-09-01

    Rheumatoid arthritis is a chronic disease affecting the joints. Treatment can include immobilisation of the affected joint with a custom-fitting splint, which is typically fabricated by hand from low temperature thermoplastic, but the approach poses several limitations. This study focused on the evaluation, by finite element analysis, of additive manufacturing techniques for wrist splints in order to improve upon the typical splinting approach. An additive manufactured/3D printed splint, specifically designed to be built using Objet Connex multi-material technology and a virtual model of a typical splint, digitised from a real patient-specific splint using three-dimensional scanning, were modelled in computer-aided design software. Forty finite element analysis simulations were performed in flexion-extension and radial-ulnar wrist movements to compare the displacements and the stresses. Simulations have shown that for low severity loads, the additive manufacturing splint has 25%, 76% and 27% less displacement in the main loading direction than the typical splint in flexion, extension and radial, respectively, while ulnar values were 75% lower in the traditional splint. For higher severity loads, the flexion and extension movements resulted in deflections that were 24% and 60%, respectively, lower in the additive manufacturing splint. However, for higher severity loading, the radial defection values were very similar in both splints and ulnar movement deflection was higher in the additive manufacturing splint. A physical prototype of the additive manufacturing splint was also manufactured and was tested under normal conditions to validate the finite element analysis data. Results from static tests showed maximum displacements of 3.46, 0.97, 3.53 and 2.51 mm flexion, extension, radial and ulnar directions, respectively. According to these results, the present research argues that from a technical point of view, the additive manufacturing splint design stands at the same or even better level of performance in displacements and stress values in comparison to the typical low temperature thermoplastic approach and is therefore a feasible approach to splint design and manufacture.

  20. Visual Search in Typically Developing Toddlers and Toddlers with Fragile X or Williams Syndrome

    ERIC Educational Resources Information Center

    Scerif, Gaia; Cornish, Kim; Wilding, John; Driver, Jon; Karmiloff-Smith, Annette

    2004-01-01

    Visual selective attention is the ability to attend to relevant visual information and ignore irrelevant stimuli. Little is known about its typical and atypical development in early childhood. Experiment 1 investigates typically developing toddlers' visual search for multiple targets on a touch-screen. Time to hit a target, distance between…

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