Sample records for ulrika kvist darnell
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Cell-Cell Adhesion and Breast Cancer.
1998-01-01
Lodish, H., Baltimore, D., Berk, A., Zipurski, S. L, Matsudaira, P., and J. Darnell. (1995). Molecular Cell Biology. Scientific American Books , New...Bruhn, L., Wedlich, D., Grosschedl, R., and Birchmeier, W. (1996) Nature 382, 638-642 6. Molenaar , M., van de Wetering, M., Oosterwegel, M., Peterson
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Check This, Mate: Chess Moves Kids.
ERIC Educational Resources Information Center
Vail, Kathleen
1995-01-01
According to Irene Dixon-Darnell, a 75-year-old great-grandmother who runs a chess-education program in the Washoe (Nevada) County Schools, chess can win-over some difficult students. She believes the ancient game of strategy teaches children to focus, encourages them to think critically and creatively, and even cures emotional wounds. Research…
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Education, Learning, and Communications, Ecology and the Undergraduate Curriculum, Session 1.
ERIC Educational Resources Information Center
Darnell, Rezneat M.; And Others
This set of two audio cassette tapes was recorded at the 1969 AAAS meeting on Ecology and the undergraduate curriculum. Four papers were presented each followed by a question and answer session. Dr. Darnell presented a paper titled "The New Ecology." The paper outlined the historical roots of ecology and defined the new perspectives of ecology,…
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1987-08-24
became possible with the development of practical methods for the propagation of poliovirus in cultured cells, the development of plaque assays...definition of the essential nutrients in cultured cells, and the purification, crystalization and physicochemical characterization of poliovirus ...Levintow, 1974). Information on viral replication of the most conunonly studied picornavirus, human poliovirus , was reviewed by Darnell and Eagle (1960
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2016-12-01
STATEMENT INFORMATION TO DETERMINE THE FINANCIAL HEALTH OF DOD CONTRACTORS December 2016 By: Timothy J. Grant Tony L. Ingram Darnell D...AND SUBTITLE FINANCIAL HEALTH INDICATORS: AN ANALYSIS OF FINANCIAL STATEMENT INFORMATION TO DETERMINE THE FINANCIAL HEALTH OF DOD CONTRACTORS 5...government contracting officers must be able to determine the financial health of prospective contractors . In fact, according to the Federal Acquisition
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Special Warfare: A Selected Bibliography.
1983-10-01
G8234 1982) 31. Chaliand, Gerard. Revolution in the Third World: Myth and Prosnects. New York: Viking Pres, 1977. (D842 .C45) 32. Clutterbuck, Richard ...L. Guerrillas and Terrorists. London: Faber and Faber, 1977. (HV6431 .C61) 33. Clutterbuck, Richard L. The Long. Lona War: Counterinsurgency in Malaya...Boulder: Panther, 1965. (U240 D3) 39. Darnell, Richard J. Civic Action Program in the Armed Forces. Fort Belvoir: US Army Combat Developments Command
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1980-02-01
M. Darnell,* Richard W. Heard,* Robert C. Cashner,* and Olivia House* e Graduate Modeling Robert E. Hinchee and Linda A. Deegan Students Grassbeds...James H. Stone, B. T. Gael, Linda A. Deegan , Robert E. Hinchee, John W. Day, Jr., Leonard M. Bahr, Jr., and R. E. Turner R. C. Cashner is affiliated with...Sciences Linda A. Deegan , Graduate Assistant David D. Dow, Research Associate III Nancy A. Drummond, Graduate Assistant Marion Fannaly, Research Associate
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The Scholar Identity Institute: Guiding Darnel and Other Black Males
ERIC Educational Resources Information Center
Whiting, Gilman W.
2009-01-01
Despite the major push for higher student outcomes in graduation, school achievement, and test scores, even when legislated (NCLB, 2001), too many students fail to persist in school, often choosing to drop out as their last resort (Bridgeland, DiIulio, & Morison, 2006). Specifically, one third of the nation's students drop out of school, even when…
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Simoneau, Guy G
2016-04-01
During the American Physical Therapy Association's Combined Sections Meeting in Anaheim, California in February 2016, JOSPT recognized the authors of the most outstanding research and clinical practice manuscripts published in JOSPT during the 2015 calendar year. The 2015 JOSPT Excellence in Research Award was presented to Björn Aasa, Lars Berglund, Peter Michaelson, and Ulrika Aasa for their paper titled "Individualized Low-Load Motor Control Exercises and Education Versus a High-Load Lifting Exercise and Education to Improve Activity, Pain Intensity, and Physical Performance in Patients With Low Back Pain: A Randomized Controlled Trial." The 2015 George J. Davies-James A. Gould Excellence in Clinical Inquiry Award was presented to Anne Benjaminse, Alli Gokeler, Bert Otten, Ariel V. Dowling, Avery Faigenbaum, Kevin R. Ford, Timothy E. Hewett, James A. Onate, and Gregory D. Myer for their work titled "Optimization of the Anterior Cruciate Ligament Injury Prevention Paradigm: Novel Feedback Techniques to Enhance Motor Learning and Reduce Injury Risk."
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5' termini of poliovirus RNA: difference between virion and nonencapsidated 35S RNA.
Fernandez-Muñoz, R; Lavi, U
1977-01-01
Poliovirus cytoplasmic, nonencapsidated 35S RNA yields approximately one pUp per molecule upon T2 RNase digestion, indicating that this RNA has the same 5' end as the polyribosome-associated viral RNA fraction. Double-stranded, replicative form RNA after the same treatment yielded approximately four pNp structures per molecule, 65% of which was pUp. In contrast, the 35S RNA from mature virions contained no detectable pNp, indicating that the 5' end of the virion RNA is different from that of the nonencapsidated RNA. None of the above molecules contained pppNp, ppNp, or GpppNp structures present in host mRNA. The virion RNA molecules, as we have shown previously for thenonencapsidated 35S viral RNA (Fernandez-Muñoz and Darnell, 1976), is not labeled with [methyl-3H]methionine. PMID:189096
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NASA Astrophysics Data System (ADS)
Zhang, Wendy
I will describe works from a collaboration between physics and glaciology that grew out of interactions at the Computations in Science seminar Leo Kadanoff organized at the University of Chicago. The first project considers the interaction between ocean waves and Antarctic ice shelves, large floating portions of ice formed by glacial outflows. Back-of-envelop calculation and seismic sensor data suggest that crevasses may be distributed within an ice shelf to shield it from wave energy. We also examine numerical scenarios in which changes in environmental forcing causes the ice shelf to fail catastrophically. The second project investigates the aftermath of iceberg calving off glacier terminus in Greenland using data recorded via time-lapse camera and terrestrial radar. Our observations indicate that the mélange of icebergs within the fjord experiences widespread jamming during a calving event and therefore is always close to being in a jammed state during periods of terminus quiescence. Joint work with Jason Amundson, Ivo R. Peters, Julian Freed Brown, Nicholas Guttenberg, Justin C Burton, L. Mac Cathles, Ryan Cassotto, Mark Fahnestock, Kristopher Darnell, Martin Truffer, Dorian S. Abbot and Douglas MacAyeal. Kadanoff Session DCMP.
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Food and Drug Administration workshop on indirect mechanisms of carcinogenesis.
Poirier, L A
1996-01-01
A workshop sponsored by the Food and Drug Administration (FDA) was held on March 4-5, 1996, at the Lister Hill Auditorium of the National Institutes of Health (NIH) Campus in Bethesda, Maryland. The workshop considered both the scientific aspects and the regulatory implications of indirect-acting carcinogens. A wide variety of agents and of prospective mechanisms was discussed. The organizing committee for the workshop consisted of Drs. James Farrelly and Joseph DeGeorge of the Center for Drug Evaluation and Research (CDER), Ronald J. Lorentzen and Sidney Green of the Center for Food Safety and Applied Nutrition (CFSAN), Martin D. Green of the Center for Biologics, Evaluation and Research (CBER), C. Darnell Jackson and Lionel A. Poirier of the National Center for Toxicological Research (NCTR). Rosalie K. Elespuru of the Center for Devices and Radiological Health (CDRH), and David G. Longfellow of the National Cancer Institute (NCI). Following an introduction by Dr. Poirier, who provided a description of indirect carcinogens, the major talks were grouped into three formal sessions: indirect-acting compounds and agents of FDA interest, biological and biochemical endpoints commonly seen with indirect agents, and specific problems associated with the indirect-acting compounds. A panel discussion followed and the concluding remarks were made by Dr. Bernard A. Schwetz, Associate Commissioner for Science, FDA.
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Small molecule inhibition of FOXM1: How to bring a novel compound into genomic context.
Marsico, Giovanni; Gormally, Michael V
2015-03-01
Deregulation of transcription factor (TF) networks is emerging as a major pathogenic event in many human cancers (Darnell, 2002 [1]; Libermann and Zerbini, 2006 [2]; Laoukili et al., 2007 [3]). Small molecule intervention is an attractive avenue to understand TF regulatory mechanisms in healthy and disease state, as well as for exploiting these targets therapeutically (Koehler et al., 2003 [4]; Berg, 2008 [5]; Koehler, 2010 [6]). However, because of their physico-chemical properties, TF targeting has been proven to be difficult (Verdine and Walensky, 2007 [7]). The TF FOXM1 is an important mitotic player (Wonsey and Follettie, 2005 [8]; Laoukili et al., 2005 [9]; McDonald, 2005 [10]) also implicated in cancer progression (Laoukili et al., 2007 [3]; Teh, 2011 [11]; Koo, 2012 [12]) and drug resistance development (Kwok et al., 2010 [13]; Carr et al., [14]). Therefore, its inhibition is an attractive goal for cancer therapy. Here, we describe a computational biology approach, by giving detailed insights into methodologies and technical results, which was used to analyze the transcriptional RNA-Seq data presented in our previous work (Gormally et al., 2014 [20]). Our Bioinformatics analysis shed light on the cellular effect of a novel FOXM1 inhibitor (FDI-6) newly identified through a biophysical screen. The data for this report is available at the public GEO repository (accession number http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE58626).
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The role of cooperative iceberg capsize during ice-shelf disintegration
NASA Astrophysics Data System (ADS)
Wilder, W. G.; Burton, J. C.; Amundson, J. M.; Cathles, L. M.; Zhang, W. W.
2011-12-01
The physical processes responsible for the sudden, rapid collapse of Antarctic ice-shelves (Larsen B, in 2002; Wilkins, in 2008) are poorly understood. Observations are limited to a handful of satellite images. Thus we have undertaken a series of laboratory-scale experiments using a water-filled tank and "ice" made from buoyant plastic blocks to investigate these processes. Previous experiments have quantified how gravitational potential energy of single-iceberg capsize is converted to other forms of energy [described in Burton et al., submitted], including hydrodynamic forms that may feed back on the ice shelf to cause additional calving. The new experiments reported here examine the energetics of hydrodynamically coupled icebergs that exhibit collective behaviors qualitatively similar to features observed in satellite imagery. Our results suggest that there is a critical proximity at which icebergs will capsize in the same direction an overwhelming majority of the time (cooperative capsize), and a significant part of the gravitational potential energy is converted into translational kinetic energy. We speculate that the residual translational energy observed in our experiments may explain the significant expansion rate (~1 meter/second) of collapsing Antarctic ice-shelves. Burton, J. C., J. M. Amundson, D. S. Abbot, A. Boghosian, L. M. Cathles, S. Correa-Legisos, K. N. Darnell, N. Guttenberg, D. M. Holland, and D. R. MacAyeal. submitted. Laboratory investigations of iceberg-capsize dynamics, energy dissipation and tsunamigenesis. J. Geophys. Res.
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Thomas, Kristin; Müssener, Ulrika; Linderoth, Catharina; Karlsson, Nadine; Bendtsen, Preben; Bendtsen, Marcus
2018-06-25
from establishing which content forms an effective intervention, the optimal length of an alcohol intervention targeting students also needs to be addressed in future studies. International Standard Randomised Controlled Trial Number ISRCTN95054707; http://www.isrctn.com/ISRCTN95054707 (Archived by WebCite at http://www.webcitation.org/70Ax4vXhd). ©Kristin Thomas, Ulrika Müssener, Catharina Linderoth, Nadine Karlsson, Preben Bendtsen, Marcus Bendtsen. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 25.06.2018.
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Koonin, Eugene V
2006-01-01
ancestors of spliceosomal introns, indeed, have existed since the earliest stages of life's evolution, in a formal agreement with the introns-early scenario. However, there is no evidence that these ancient introns ever became widespread before the emergence of eukaryotes, hence, the central tenet of introns-early, the role of introns in early evolution of proteins, has no support. However, the demonstration that numerous introns invaded eukaryotic genes at the outset of eukaryotic evolution and that subsequent intron gain has been limited in many eukaryotic lineages implicates introns as an ancestral feature of eukaryotic genomes and refutes radical versions of introns-late. Perhaps, most importantly, I argue that the intron invasion triggered other pivotal events of eukaryogenesis, including the emergence of the spliceosome, the nucleus, the linear chromosomes, the telomerase, and the ubiquitin signaling system. This concept of eukaryogenesis, in a sense, revives some tenets of the exon hypothesis, by assigning to introns crucial roles in eukaryotic evolutionary innovation. Conclusion The scenario of the origin and evolution of introns that is best compatible with the results of comparative genomics and theoretical considerations goes as follows: self-splicing introns since the earliest stages of life's evolution – numerous spliceosomal introns invading genes of the emerging eukaryote during eukaryogenesis – subsequent lineage-specific loss and gain of introns. The intron invasion, probably, spawned by the mitochondrial endosymbiont, might have critically contributed to the emergence of the principal features of the eukaryotic cell. This scenario combines aspects of the introns-early and introns-late views. Reviewers this article was reviewed by W. Ford Doolittle, James Darnell (nominated by W. Ford Doolittle), William Martin, and Anthony Poole. PMID:16907971
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NASA Astrophysics Data System (ADS)
Johnson, D.
2013-12-01
Abstract: Researchers, policymakers, business, and industry have indicated that the United States will experience a future shortage of professionals in the Science, Technology, Engineering, and Mathematics (STEM) fields. Several strategies have been suggested to address this impending shortage, one of which includes increasing the representation of females and minorities in the STEM fields. In order to increase the representation of underrepresented students in the STEM fields, it is important to understand the motivational factors that impact underrepresented students' interest in STEM academics and extracurricular programs. Research indicates that greater confidence leads to greater interest and vice versa (Denissen et al., 2007). In this paper, the mathematics research team examined the role of practical research experience during the summer for talented minority secondary students studying in STEM fields. An undergraduate research mathematics team focused on the link between summer research and the choice of an undergraduate discipline. A Chi Square Statistical Test was used to examine Likert Scale results on the attitude of students participating in the 2006-2012 Center for Remote Sensing of Ice Sheets (CReSIS) Summer Research Programs for secondary students. This research was performed at Elizabeth City State University located in northeastern North Carolina about the factors that impact underrepresented students' choices of STEM related majors in college. Results can be used to inform and guide educators, administrators, and policy makers in developing programs and policy that support and encourage the STEM development of underrepresented students. Index Terms: Science, Technology, Engineering, and Mathematics (STEM), Underrepresented students
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Obituary: Ludwig Friedrich Oster, 1931-2003
NASA Astrophysics Data System (ADS)
Sofia, Sabatino; Altschuler, Martin D.
2003-12-01
Ludwig Friedrich Oster died at the Anchorage Nursing and Rehabilitation Center in Salisbury, MD on 28 February 2003, of complications from advanced Alzheimer's disease. He is survived by his wife Cheryl M. (Oroian) and his two children by a previous marriage, Ulrika and Mattias Oster. He had a distinguished career both as a researcher in solar physics and as a science administrator in the National Science Foundation. Ludwig was born on 8 March 1931 in Konstanz, Germany and emigrated to the U.S. in 1958, acquiring American citizenship in 1963. His mother and father were Emma Josefine (Schwarz) and Ludwig Friedrich Oster. He got a BS degree in physics at the University of Freiburg under the guidance of Prof. K. O. Kiepenheuer in 1951, and a MS (1954) and PhD from the University of Kiel in 1956 under the guidance of Prof. A. Unsold. From 1956 to 1958 he was a Fellow of the German Science Council at Kiel and, upon his arrival to the US in 1958, he became a Postdoctoral Research Associate in the Physics Department of Yale University. He became an Assistant Professor of Physics and Astrophysics at Yale in 1960 and five years later he was promoted to Associate Professor. In 1967 he became an Associate Professor of Physics and Astrophysics at the University of Colorado and a Fellow of the Joint Institute for Laboratory Astrophysics; he was promoted to Full Professor in 1970. In 1981 he was a Visiting Professor at Johns Hopkins University, and shortly thereafter became a National Research Council Senior Associate at NASA/Goddard Space Flight Center in Greenbelt, MD, where he worked on solar variability. He joined the National Science Foundation in 1983, where he became the Program Manager for the National Radio Astronomy Observatory in the Division of Astronomical Sciences of the Foundation; he remained there until his retirement in 1996. His early work, started in Germany and continued at Yale, concerned radiation mechanisms related to solar phenomena. His works on