Sample records for ultra-long timescale dynamical

  1. Slow Cortical Dynamics and the Accumulation of Information over Long Timescales

    PubMed Central

    Honey, Christopher J.; Thesen, Thomas; Donner, Tobias H.; Silbert, Lauren J.; Carlson, Chad E.; Devinsky, Orrin; Doyle, Werner K.; Rubin, Nava; Heeger, David J.; Hasson, Uri

    2012-01-01

    SUMMARY Making sense of the world requires us to process information over multiple timescales. We sought to identify brain regions that accumulate information over short and long timescales and to characterize the distinguishing features of their dynamics. We recorded electrocorticographic (ECoG) signals from individuals watching intact and scrambled movies. Within sensory regions, fluctuations of high-frequency (64–200 Hz) power reliably tracked instantaneous low-level properties of the intact and scrambled movies. Within higher order regions, the power fluctuations were more reliable for the intact movie than the scrambled movie, indicating that these regions accumulate information over relatively long time periods (several seconds or longer). Slow (<0.1 Hz) fluctuations of high-frequency power with time courses locked to the movies were observed throughout the cortex. Slow fluctuations were relatively larger in regions that accumulated information over longer time periods, suggesting a connection between slow neuronal population dynamics and temporally extended information processing. PMID:23083743

  2. Long-timescale motions in glycerol-monopalmitate lipid bilayers investigated using molecular dynamics simulation.

    PubMed

    Laner, Monika; Horta, Bruno A C; Hünenberger, Philippe H

    2015-02-01

    The occurrence of long-timescale motions in glycerol-1-monopalmitate (GMP) lipid bilayers is investigated based on previously reported 600 ns molecular dynamics simulations of a 2×8×8 GMP bilayer patch in the temperature range 302-338 K, performed at three different hydration levels, or in the presence of the cosolutes methanol or trehalose at three different concentrations. The types of long-timescale motions considered are: (i) the possible phase transitions; (ii) the precession of the relative collective tilt-angle of the two leaflets in the gel phase; (iii) the trans-gauche isomerization of the dihedral angles within the lipid aliphatic tails; and (iv) the flipping of single lipids across the two leaflets. The results provide a picture of GMP bilayers involving a rich spectrum of events occurring on a wide range of timescales, from the 100-ps range isomerization of single dihedral angles, via the 100-ns range of tilt precession motions, to the multi-μs range of phase transitions and lipid-flipping events. Copyright © 2014 Elsevier Inc. All rights reserved.

  3. Continuous Timescale Long-Short Term Memory Neural Network for Human Intent Understanding

    PubMed Central

    Yu, Zhibin; Moirangthem, Dennis S.; Lee, Minho

    2017-01-01

    Understanding of human intention by observing a series of human actions has been a challenging task. In order to do so, we need to analyze longer sequences of human actions related with intentions and extract the context from the dynamic features. The multiple timescales recurrent neural network (MTRNN) model, which is believed to be a kind of solution, is a useful tool for recording and regenerating a continuous signal for dynamic tasks. However, the conventional MTRNN suffers from the vanishing gradient problem which renders it impossible to be used for longer sequence understanding. To address this problem, we propose a new model named Continuous Timescale Long-Short Term Memory (CTLSTM) in which we inherit the multiple timescales concept into the Long-Short Term Memory (LSTM) recurrent neural network (RNN) that addresses the vanishing gradient problem. We design an additional recurrent connection in the LSTM cell outputs to produce a time-delay in order to capture the slow context. Our experiments show that the proposed model exhibits better context modeling ability and captures the dynamic features on multiple large dataset classification tasks. The results illustrate that the multiple timescales concept enhances the ability of our model to handle longer sequences related with human intentions and hence proving to be more suitable for complex tasks, such as intention recognition. PMID:28878646

  4. Long-timescale molecular dynamics simulations elucidate the dynamics and kinetics of exposure of the hydrophobic patch in troponin C.

    PubMed

    Lindert, Steffen; Kekenes-Huskey, Peter M; McCammon, J Andrew

    2012-10-17

    Troponin (Tn) is an important regulatory protein in the thin-filament complex of cardiomyocytes. Calcium binding to the troponin C (TnC) subunit causes a change in its dynamics that leads to the transient opening of a hydrophobic patch on TnC's surface, to which a helix of another subunit, troponin I (TnI), binds. This process initiates contraction, making it an important target for studies investigating the detailed molecular processes that underlie contraction. Here we use microsecond-timescale Anton molecular dynamics simulations to investigate the dynamics and kinetics of the opening transition of the TnC hydrophobic patch. Free-energy differences for opening are calculated for wild-type Ca(2+)-bound TnC (∼8 kcal/mol), V44Q Ca(2+)-bound TnC (3.2 kcal/mol), E40A Ca(2+)-bound TnC (∼12 kcal/mol), and wild-type apo TnC (∼20 kcal/mol). These results suggest that the mutations have a profound impact on the frequency with which the hydrophobic patch presents to TnI. In addition, these simulations corroborate that cardiac wild-type TnC does not open on timescales relevant to contraction without calcium being bound. Copyright © 2012 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  5. Adaptive dynamics on an environmental gradient that changes over a geological time-scale.

    PubMed

    Fortelius, Mikael; Geritz, Stefan; Gyllenberg, Mats; Toivonen, Jaakko

    2015-07-07

    The standard adaptive dynamics framework assumes two timescales, i.e. fast population dynamics and slow evolutionary dynamics. We further assume a third timescale, which is even slower than the evolutionary timescale. We call this the geological timescale and we assume that slow climatic change occurs within this timescale. We study the evolution of our model population over this very slow geological timescale with bifurcation plots of the standard adaptive dynamics framework. The bifurcation parameter being varied describes the abiotic environment that changes over the geological timescale. We construct evolutionary trees over the geological timescale and observe both gradual phenotypic evolution and punctuated branching events. We concur with the established notion that branching of a monomorphic population on an environmental gradient only happens when the gradient is not too shallow and not too steep. However, we show that evolution within the habitat can produce polymorphic populations that inhabit steep gradients. What is necessary is that the environmental gradient at some point in time is such that the initial branching of the monomorphic population can occur. We also find that phenotypes adapted to environments in the middle of the existing environmental range are more likely to branch than phenotypes adapted to extreme environments. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. Dynamic correlations at different time-scales with empirical mode decomposition

    NASA Astrophysics Data System (ADS)

    Nava, Noemi; Di Matteo, T.; Aste, Tomaso

    2018-07-01

    We introduce a simple approach which combines Empirical Mode Decomposition (EMD) and Pearson's cross-correlations over rolling windows to quantify dynamic dependency at different time scales. The EMD is a tool to separate time series into implicit components which oscillate at different time-scales. We apply this decomposition to intraday time series of the following three financial indices: the S&P 500 (USA), the IPC (Mexico) and the VIX (volatility index USA), obtaining time-varying multidimensional cross-correlations at different time-scales. The correlations computed over a rolling window are compared across the three indices, across the components at different time-scales and across different time lags. We uncover a rich heterogeneity of interactions, which depends on the time-scale and has important lead-lag relations that could have practical use for portfolio management, risk estimation and investment decisions.

  7. Multiple time-scales and the developmental dynamics of social systems.

    PubMed

    Flack, Jessica C

    2012-07-05

    To build a theory of social complexity, we need to understand how aggregate social properties arise from individual interaction rules. Here, I review a body of work on the developmental dynamics of pigtailed macaque social organization and conflict management that provides insight into the mechanistic causes of multi-scale social systems. In this model system coarse-grained, statistical representations of collective dynamics are more predictive of the future state of the system than the constantly in-flux behavioural patterns at the individual level. The data suggest that individuals can perceive and use these representations for strategical decision-making. As an interaction history accumulates the coarse-grained representations consolidate. This constrains individual behaviour and provides the foundations for new levels of organization. The time-scales on which these representations change impact whether the consolidating higher-levels can be modified by individuals and collectively. The time-scales appear to be a function of the 'coarseness' of the representations and the character of the collective dynamics over which they are averages. The data suggest that an advantage of multiple timescales is that they allow social systems to balance tradeoffs between predictability and adaptability. I briefly discuss the implications of these findings for cognition, social niche construction and the evolution of new levels of organization in biological systems.

  8. Perspective: Markov models for long-timescale biomolecular dynamics.

    PubMed

    Schwantes, C R; McGibbon, R T; Pande, V S

    2014-09-07

    Molecular dynamics simulations have the potential to provide atomic-level detail and insight to important questions in chemical physics that cannot be observed in typical experiments. However, simply generating a long trajectory is insufficient, as researchers must be able to transform the data in a simulation trajectory into specific scientific insights. Although this analysis step has often been taken for granted, it deserves further attention as large-scale simulations become increasingly routine. In this perspective, we discuss the application of Markov models to the analysis of large-scale biomolecular simulations. We draw attention to recent improvements in the construction of these models as well as several important open issues. In addition, we highlight recent theoretical advances that pave the way for a new generation of models of molecular kinetics.

  9. Multiple time-scales and the developmental dynamics of social systems

    PubMed Central

    Flack, Jessica C.

    2012-01-01

    To build a theory of social complexity, we need to understand how aggregate social properties arise from individual interaction rules. Here, I review a body of work on the developmental dynamics of pigtailed macaque social organization and conflict management that provides insight into the mechanistic causes of multi-scale social systems. In this model system coarse-grained, statistical representations of collective dynamics are more predictive of the future state of the system than the constantly in-flux behavioural patterns at the individual level. The data suggest that individuals can perceive and use these representations for strategical decision-making. As an interaction history accumulates the coarse-grained representations consolidate. This constrains individual behaviour and provides the foundations for new levels of organization. The time-scales on which these representations change impact whether the consolidating higher-levels can be modified by individuals and collectively. The time-scales appear to be a function of the ‘coarseness’ of the representations and the character of the collective dynamics over which they are averages. The data suggest that an advantage of multiple timescales is that they allow social systems to balance tradeoffs between predictability and adaptability. I briefly discuss the implications of these findings for cognition, social niche construction and the evolution of new levels of organization in biological systems. PMID:22641819

  10. A Dynamical System Approach Explaining the Process of Development by Introducing Different Time-scales.

    PubMed

    Hashemi Kamangar, Somayeh Sadat; Moradimanesh, Zahra; Mokhtari, Setareh; Bakouie, Fatemeh

    2018-06-11

    A developmental process can be described as changes through time within a complex dynamic system. The self-organized changes and emergent behaviour during development can be described and modeled as a dynamical system. We propose a dynamical system approach to answer the main question in human cognitive development i.e. the changes during development happens continuously or in discontinuous stages. Within this approach there is a concept; the size of time scales, which can be used to address the aforementioned question. We introduce a framework, by considering the concept of time-scale, in which "fast" and "slow" is defined by the size of time-scales. According to our suggested model, the overall pattern of development can be seen as one continuous function, with different time-scales in different time intervals.

  11. Extending atomistic simulation timescale in solid/liquid systems: crystal growth from solution by a parallel-replica dynamics and continuum hybrid method.

    PubMed

    Lu, Chun-Yaung; Voter, Arthur F; Perez, Danny

    2014-01-28

    Deposition of solid material from solution is ubiquitous in nature. However, due to the inherent complexity of such systems, this process is comparatively much less understood than deposition from a gas or vacuum. Further, the accurate atomistic modeling of such systems is computationally expensive, therefore leaving many intriguing long-timescale phenomena out of reach. We present an atomistic/continuum hybrid method for extending the simulation timescales of dynamics at solid/liquid interfaces. We demonstrate the method by simulating the deposition of Ag on Ag (001) from solution with a significant speedup over standard MD. The results reveal specific features of diffusive deposition dynamics, such as a dramatic increase in the roughness of the film.

  12. Timescales for exploratory tactical behaviour in football small-sided games.

    PubMed

    Ric, Angel; Hristovski, Robert; Gonçalves, Bruno; Torres, Lorena; Sampaio, Jaime; Torrents, Carlota

    2016-09-01

    The aim of this study was to identify the dynamics of tactical behaviour emerging on different timescales in football small-sided games and to quantify short- and long-term exploratory behaviour according to the number of opponents. Two teams of four professional male footballers played small-sided games against two different teams with a variable number of opponents (3, 5 and 7). Data were collected using a combination of systematic observation and a non-differential global positioning system (15 Hz). The temporal diversity and structural flexibility of the players were determined by calculating the dynamic overlap order parameter q, entropy and trapping strength. Analysis of the exploratory dynamics revealed two different timescales, forming a different metastable landscape of action for each constraint. Fast dynamics lasted on average a few seconds and consisted of changes in tactical patterns. The long timescale corresponded to the shared tasks of offence and defence lasting tens of seconds. The players' tactical diversity decreased with an increasing number of opponents, especially in defence. Manipulating numerical imbalance is likely to promote changes in the diversity, unpredictability and flexibility of tactical solutions. The fact that the temporally nested structure of constraints shaped the emergence of tactical behaviour provides a new rationale for practice task design. The manipulation of numerical imbalance on the timescale of a few tens of seconds, on which the exploratory behaviour of players saturates, may help coaches to optimise the exploratory efficiency of the small-sided games.

  13. Bridging the Timescales of Single-Cell and Population Dynamics

    NASA Astrophysics Data System (ADS)

    Jafarpour, Farshid; Wright, Charles S.; Gudjonson, Herman; Riebling, Jedidiah; Dawson, Emma; Lo, Klevin; Fiebig, Aretha; Crosson, Sean; Dinner, Aaron R.; Iyer-Biswas, Srividya

    2018-04-01

    How are granular details of stochastic growth and division of individual cells reflected in smooth deterministic growth of population numbers? We provide an integrated, multiscale perspective of microbial growth dynamics by formulating a data-validated theoretical framework that accounts for observables at both single-cell and population scales. We derive exact analytical complete time-dependent solutions to cell-age distributions and population growth rates as functionals of the underlying interdivision time distributions, for symmetric and asymmetric cell division. These results provide insights into the surprising implications of stochastic single-cell dynamics for population growth. Using our results for asymmetric division, we deduce the time to transition from the reproductively quiescent (swarmer) to the replication-competent (stalked) stage of the Caulobacter crescentus life cycle. Remarkably, population numbers can spontaneously oscillate with time. We elucidate the physics leading to these population oscillations. For C. crescentus cells, we show that a simple measurement of the population growth rate, for a given growth condition, is sufficient to characterize the condition-specific cellular unit of time and, thus, yields the mean (single-cell) growth and division timescales, fluctuations in cell division times, the cell-age distribution, and the quiescence timescale.

  14. Black Hole Hyperaccretion Inflow–Outflow Model. I. Long and Ultra-long Gamma-Ray Bursts

    NASA Astrophysics Data System (ADS)

    Liu, Tong; Song, Cui-Ying; Zhang, Bing; Gu, Wei-Min; Heger, Alexander

    2018-01-01

    Long-duration gamma-ray bursts (LGRBs) and ultra-LGRBs (ULGRBs) originate from collapsars, in the center of which a newborn rotating stellar-mass black hole (BH) surrounded by a massive accretion disk may form. In the scenario of the BH hyperaccretion inflow–outflow model and Blandford–Znajek (BZ) mechanism to trigger gamma-ray bursts (GRBs), the real accretion rate to power a BZ jet is far lower than the mass supply rate from the progenitor star. The characteristics of the progenitor stars can be constrained by GRB luminosity observations, and the results exceed usual expectations. LGRBs lasting from several seconds to tens of seconds in the rest frame may originate from solar-metallicity (Z∼ 1 {Z}ȯ , where Z and {Z}ȯ are the metallicities of progenitor stars and the Sun), massive (M≳ 34 {M}ȯ , where M and {M}ȯ are the masses of progenitor stars and the Sun) stars or some zero-metallicity (Z∼ 0) stars. A fraction of low-metallicity (Z≲ {10}-2 {Z}ȯ ) stars, including Population III stars, can produce ULGRBs such as GRB 111209A. The fraction of LGRBs lasting less than tens of seconds in the rest frame is more than 40%, which cannot conform to the fraction of the demanded type of progenitor star. It possibly implies that the activity timescale of the central engine may be much longer than the observed timescale of prompt emission phase, as indicated by X-ray late-time activities. Alternatively, LGRBs and ULGRBs may be powered by a millisecond magnetar central engine.

  15. Unsupervised Discovery of Demixed, Low-Dimensional Neural Dynamics across Multiple Timescales through Tensor Component Analysis.

    PubMed

    Williams, Alex H; Kim, Tony Hyun; Wang, Forea; Vyas, Saurabh; Ryu, Stephen I; Shenoy, Krishna V; Schnitzer, Mark; Kolda, Tamara G; Ganguli, Surya

    2018-06-27

    Perceptions, thoughts, and actions unfold over millisecond timescales, while learned behaviors can require many days to mature. While recent experimental advances enable large-scale and long-term neural recordings with high temporal fidelity, it remains a formidable challenge to extract unbiased and interpretable descriptions of how rapid single-trial circuit dynamics change slowly over many trials to mediate learning. We demonstrate a simple tensor component analysis (TCA) can meet this challenge by extracting three interconnected, low-dimensional descriptions of neural data: neuron factors, reflecting cell assemblies; temporal factors, reflecting rapid circuit dynamics mediating perceptions, thoughts, and actions within each trial; and trial factors, describing both long-term learning and trial-to-trial changes in cognitive state. We demonstrate the broad applicability of TCA by revealing insights into diverse datasets derived from artificial neural networks, large-scale calcium imaging of rodent prefrontal cortex during maze navigation, and multielectrode recordings of macaque motor cortex during brain machine interface learning. Copyright © 2018 Elsevier Inc. All rights reserved.

  16. Spacing Repetitions Over Long Timescales: A Review and a Reconsolidation Explanation

    PubMed Central

    Smith, Christopher D.; Scarf, Damian

    2017-01-01

    Recent accounts of the spacing effect have proposed molecular explanations that explain spacing over short, but not long timescales. In the first half of this paper, we review research on the spacing effect that has employed spaces of 24 h or more across skill-related tasks, language-related tasks and generalization for adults and children. Throughout this review, we distinguish between learning and retention by defining learning (or acquisition) as performance at the end of training and retention as performance after a delay period. Using this distinction, we find age- and task-related differences in the manifestation of the spacing effect over long timescales. In the second half of this paper, we discuss a reconsolidation account of the spacing effect. In particular, we review the evidence that suggests the spacing of repetitions influences the subsequent consolidation and reconsolidation processes; we explain how a reconsolidation account may explain the findings for learning; the inverted-U curve for retention; and compare the reconsolidation account with previous consolidation accounts of the spacing effect. PMID:28676769

  17. N-scaling of timescales in long-range N-body quantum systems

    NASA Astrophysics Data System (ADS)

    Kastner, Michael

    2017-01-01

    Long-range interacting many-body systems exhibit a number of peculiar and intriguing properties. One of those is the scaling of relaxation times with the number N of particles in a system. In this paper I give a survey of results on long-range quantum spin models that illustrate this scaling behaviour, and provide indications for its common occurrence by making use of Lieb-Robinson bounds. I argue that these findings may help in understanding the extraordinarily short equilibration timescales predicted by typicality techniques.

  18. Dynamics analysis of the fast-slow hydro-turbine governing system with different time-scale coupling

    NASA Astrophysics Data System (ADS)

    Zhang, Hao; Chen, Diyi; Wu, Changzhi; Wang, Xiangyu

    2018-01-01

    Multi-time scales modeling of hydro-turbine governing system is crucial in precise modeling of hydropower plant and provides support for the stability analysis of the system. Considering the inertia and response time of the hydraulic servo system, the hydro-turbine governing system is transformed into the fast-slow hydro-turbine governing system. The effects of the time-scale on the dynamical behavior of the system are analyzed and the fast-slow dynamical behaviors of the system are investigated with different time-scale. Furthermore, the theoretical analysis of the stable regions is presented. The influences of the time-scale on the stable region are analyzed by simulation. The simulation results prove the correctness of the theoretical analysis. More importantly, the methods and results of this paper provide a perspective to multi-time scales modeling of hydro-turbine governing system and contribute to the optimization analysis and control of the system.

  19. An Estimation of the Logarithmic Timescale in Ergodic Dynamics

    NASA Astrophysics Data System (ADS)

    Gomez, Ignacio S.

    An estimation of the logarithmic timescale in quantum systems having an ergodic dynamics in the semiclassical limit, is presented. The estimation is based on an extension of the Krieger’s finite generator theorem for discretized σ-algebras and using the time rescaling property of the Kolmogorov-Sinai entropy. The results are in agreement with those obtained in the literature but with a simpler mathematics and within the context of the ergodic theory. Moreover, some consequences of the Poincaré’s recurrence theorem are also explored.

  20. Air plasma treatment of liquid covered tissue: long timescale chemistry

    NASA Astrophysics Data System (ADS)

    Lietz, Amanda M.; Kushner, Mark J.

    2016-10-01

    Atmospheric pressure plasmas have shown great promise for the treatment of wounds and cancerous tumors. In these applications, the sample is usually covered by a thin layer of a biological liquid. The reactive oxygen and nitrogen species (RONS) generated by the plasma activate and are processed by the liquid before the plasma produced activation reaches the tissue. The synergy between the plasma and the liquid, including evaporation and the solvation of ions and neutrals, is critical to understanding the outcome of plasma treatment. The atmospheric pressure plasma sources used in these procedures are typically repetitively pulsed. The processes activated by the plasma sources have multiple timescales—from a few ns during the discharge pulse to many minutes for reactions in the liquid. In this paper we discuss results from a computational investigation of plasma-liquid interactions and liquid phase chemistry using a global model with the goal of addressing this large dynamic range in timescales. In modeling air plasmas produced by a dielectric barrier discharge over liquid covered tissue, 5000 voltage pulses were simulated, followed by 5 min of afterglow. Due to the accumulation of long-lived species such as ozone and N x O y , the gas phase dynamics of the 5000th discharge pulse are different from those of the first pulse, particularly with regards to the negative ions. The consequences of applied voltage, gas flow, pulse repetition frequency, and the presence of organic molecules in the liquid on the gas and liquid reactive species are discussed.

  1. Determining long time-scale hyporheic zone flow paths in Antarctic streams

    USGS Publications Warehouse

    Gooseff, M.N.; McKnight, Diane M.; Runkel, R.L.; Vaughn, B.H.

    2003-01-01

    In the McMurdo Dry Valleys of Antarctica, glaciers are the source of meltwater during the austral summer, and the streams and adjacent hyporheic zones constitute the entire physical watershed; there are no hillslope processes in these systems. Hyporheic zones can extend several metres from each side of the stream, and are up to 70 cm deep, corresponding to a lateral cross-section as large as 12 m2, and water resides in the subsurface year around. In this study, we differentiate between the near-stream hyporheic zone, which can be characterized with stream tracer experiments, and the extended hyporheic zone, which has a longer time-scale of exchange. We sampled stream water from Green Creek and from the adjacent saturated alluvium for stable isotopes of D and 18O to assess the significance and extent of stream-water exchange between the streams and extended hyporheic zones over long time-scales (days to weeks). Our results show that water residing in the extended hyporheic zone is much more isotopically enriched (up to 11??? D and 2.2??? 18O) than stream water. This result suggests a long residence time within the extended hyporheic zone, during which fractionation has occured owing to summer evaporation and winter sublimation of hyporheic water. We found less enriched water in the extended hyporheic zone later in the flow season, suggesting that stream water may be exchanged into and out of this zone, on the time-scale of weeks to months. The transient storage model OTIS was used to characterize the exchange of stream water with the extended hyporheic zone. Model results yield exchange rates (??) generally an order magnitude lower (10-5 s-1) than those determined using stream-tracer techniques on the same stream. In light of previous studies in these streams, these results suggest that the hyporheic zones in Antarctic streams have near-stream zones of rapid stream-water exchange, where 'fast' biogeochemical reactions may influence water chemistry, and extended

  2. Motional timescale predictions by molecular dynamics simulations: case study using proline and hydroxyproline sidechain dynamics.

    PubMed

    Aliev, Abil E; Kulke, Martin; Khaneja, Harmeet S; Chudasama, Vijay; Sheppard, Tom D; Lanigan, Rachel M

    2014-02-01

    We propose a new approach for force field optimizations which aims at reproducing dynamics characteristics using biomolecular MD simulations, in addition to improved prediction of motionally averaged structural properties available from experiment. As the source of experimental data for dynamics fittings, we use (13) C NMR spin-lattice relaxation times T1 of backbone and sidechain carbons, which allow to determine correlation times of both overall molecular and intramolecular motions. For structural fittings, we use motionally averaged experimental values of NMR J couplings. The proline residue and its derivative 4-hydroxyproline with relatively simple cyclic structure and sidechain dynamics were chosen for the assessment of the new approach in this work. Initially, grid search and simplexed MD simulations identified large number of parameter sets which fit equally well experimental J couplings. Using the Arrhenius-type relationship between the force constant and the correlation time, the available MD data for a series of parameter sets were analyzed to predict the value of the force constant that best reproduces experimental timescale of the sidechain dynamics. Verification of the new force-field (termed as AMBER99SB-ILDNP) against NMR J couplings and correlation times showed consistent and significant improvements compared to the original force field in reproducing both structural and dynamics properties. The results suggest that matching experimental timescales of motions together with motionally averaged characteristics is the valid approach for force field parameter optimization. Such a comprehensive approach is not restricted to cyclic residues and can be extended to other amino acid residues, as well as to the backbone. Copyright © 2013 Wiley Periodicals, Inc.

  3. Motional timescale predictions by molecular dynamics simulations: Case study using proline and hydroxyproline sidechain dynamics

    PubMed Central

    Aliev, Abil E; Kulke, Martin; Khaneja, Harmeet S; Chudasama, Vijay; Sheppard, Tom D; Lanigan, Rachel M

    2014-01-01

    We propose a new approach for force field optimizations which aims at reproducing dynamics characteristics using biomolecular MD simulations, in addition to improved prediction of motionally averaged structural properties available from experiment. As the source of experimental data for dynamics fittings, we use 13C NMR spin-lattice relaxation times T1 of backbone and sidechain carbons, which allow to determine correlation times of both overall molecular and intramolecular motions. For structural fittings, we use motionally averaged experimental values of NMR J couplings. The proline residue and its derivative 4-hydroxyproline with relatively simple cyclic structure and sidechain dynamics were chosen for the assessment of the new approach in this work. Initially, grid search and simplexed MD simulations identified large number of parameter sets which fit equally well experimental J couplings. Using the Arrhenius-type relationship between the force constant and the correlation time, the available MD data for a series of parameter sets were analyzed to predict the value of the force constant that best reproduces experimental timescale of the sidechain dynamics. Verification of the new force-field (termed as AMBER99SB-ILDNP) against NMR J couplings and correlation times showed consistent and significant improvements compared to the original force field in reproducing both structural and dynamics properties. The results suggest that matching experimental timescales of motions together with motionally averaged characteristics is the valid approach for force field parameter optimization. Such a comprehensive approach is not restricted to cyclic residues and can be extended to other amino acid residues, as well as to the backbone. Proteins 2014; 82:195–215. © 2013 Wiley Periodicals, Inc. PMID:23818175

  4. Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.

    PubMed

    Choy, Meng S; Li, Yang; Machado, Luciana E S F; Kunze, Micha B A; Connors, Christopher R; Wei, Xingyu; Lindorff-Larsen, Kresten; Page, Rebecca; Peti, Wolfgang

    2017-02-16

    Protein function originates from a cooperation of structural rigidity, dynamics at different timescales, and allostery. However, how these three pillars of protein function are integrated is still only poorly understood. Here we show how these pillars are connected in Protein Tyrosine Phosphatase 1B (PTP1B), a drug target for diabetes and cancer that catalyzes the dephosphorylation of numerous substrates in essential signaling pathways. By combining new experimental and computational data on WT-PTP1B and ≥10 PTP1B variants in multiple states, we discovered a fundamental and evolutionarily conserved CH/π switch that is critical for positioning the catalytically important WPD loop. Furthermore, our data show that PTP1B uses conformational and dynamic allostery to regulate its activity. This shows that both conformational rigidity and dynamics are essential for controlling protein activity. This connection between rigidity and dynamics at different timescales is likely a hallmark of all enzyme function. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Modes of embayed beach dynamics: analysis reveals emergent timescales

    NASA Astrophysics Data System (ADS)

    Murray, K. T.; Murray, A.; Limber, P. W.; Ells, K. D.

    2013-12-01

    Embayed beaches, or beaches positioned between rocky headlands, exhibit morphologic changes over many length and time scales. Beach sediment is transported as a result of the day-to-day wave forcing, causing patterns of erosion and accretion. We use the Rocky Coastline Evolution Model (RCEM) to investigate how patterns of shoreline change depend on wave climate (the distribution of wave-approach angles) and beach characteristics. Measuring changes in beach width through time allows us to track the evolution of the shape of the beach and the movement of sand within it. By using Principle Component Analysis (PCA), these changes can be categorized into modes, where the first few modes explain the majority of the variation in the time series. We analyze these modes and how they vary as a function of wave climate and headland/bay aspect ratio. In the purposefully simple RCEM, sediment transport is wave-driven and affected by wave shadowing behind the headlands. The rock elements in our model experiments (including the headlands) are fixed and unerodable so that this analysis can focus purely on sand dynamics between the headlands, without a sand contribution from the headlands or cliffs behind the beach. The wave climate is characterized by dictating the percentage of offshore waves arriving from the left and the percentage of waves arriving from high angles (very oblique to the coastline orientation). A high-angle dominated wave climate tends to amplify coastline perturbations, whereas a lower-angle wave climate is diffusive. By changing the headland/bay aspect ratio and wave climate, we can perform PCA analysis of generalized embayed beaches with differing anatomy and wave climate forcings. Previous work using PCA analysis of embayed beaches focused on specific locations and shorter timescales (<30 years; Short and Trembanis, 2004). By using the RCEM, we can more broadly characterize beach dynamics over longer timescales. The first two PCA modes, which explain a

  6. Long-term influence of asteroids on planet longitudes and chaotic dynamics of the solar system

    NASA Astrophysics Data System (ADS)

    Woillez, E.; Bouchet, F.

    2017-11-01

    Over timescales much longer than an orbital period, the solar system exhibits large-scale chaotic behavior and can thus be viewed as a stochastic dynamical system. The aim of the present paper is to compare different sources of stochasticity in the solar system. More precisely we studied the importance of the long term influence of asteroids on the chaotic dynamics of the solar system. We show that the effects of asteroids on planets is similar to a white noise process, when those effects are considered on a timescale much larger than the correlation time τϕ ≃ 104 yr of asteroid trajectories. We computed the timescale τe after which the effects of the stochastic evolution of the asteroids lead to a loss of information for the initial conditions of the perturbed Laplace-Lagrange secular dynamics. The order of magnitude of this timescale is precisely determined by theoretical argument, and we find that τe ≃ 104 Myr. Although comparable to the full main-sequence lifetime of the sun, this timescale is considerably longer than the Lyapunov time τI ≃ 10 Myr of the solar system without asteroids. This shows that the external sources of chaos arise as a small perturbation in the stochastic secular behavior of the solar system, rather due to intrinsic chaos.

  7. Ultra Reliable Closed Loop Life Support for Long Space Missions

    NASA Technical Reports Server (NTRS)

    Jones, Harry W.; Ewert, Michael K.

    2010-01-01

    Spacecraft human life support systems can achieve ultra reliability by providing sufficient spares to replace all failed components. The additional mass of spares for ultra reliability is approximately equal to the original system mass, provided that the original system reliability is not too low. Acceptable reliability can be achieved for the Space Shuttle and Space Station by preventive maintenance and by replacing failed units. However, on-demand maintenance and repair requires a logistics supply chain in place to provide the needed spares. In contrast, a Mars or other long space mission must take along all the needed spares, since resupply is not possible. Long missions must achieve ultra reliability, a very low failure rate per hour, since they will take years rather than weeks and cannot be cut short if a failure occurs. Also, distant missions have a much higher mass launch cost per kilogram than near-Earth missions. Achieving ultra reliable spacecraft life support systems with acceptable mass will require a well-planned and extensive development effort. Analysis must determine the reliability requirement and allocate it to subsystems and components. Ultra reliability requires reducing the intrinsic failure causes, providing spares to replace failed components and having "graceful" failure modes. Technologies, components, and materials must be selected and designed for high reliability. Long duration testing is needed to confirm very low failure rates. Systems design should segregate the failure causes in the smallest, most easily replaceable parts. The system must be designed, developed, integrated, and tested with system reliability in mind. Maintenance and reparability of failed units must not add to the probability of failure. The overall system must be tested sufficiently to identify any design errors. A program to develop ultra reliable space life support systems with acceptable mass should start soon since it must be a long term effort.

  8. [An ultra-low power, wearable, long-term ECG monitoring system with mass storage].

    PubMed

    Liu, Na; Chen, Yingmin; Zhang, Wenzan; Luo, Zhangyuan; Jin, Xun; Ying, Weihai

    2012-01-01

    In this paper, we described an ultra-low power, wearable ECG system capable of long term monitoring and mass storage. This system is based on micro-chip PIC18F27J13 with consideration of its high level of integration and low power consumption. The communication with the micro-SD card is achieved through SPI bus. Through the USB, it can be connected to the computer for replay and disease diagnosis. Given its low power cost, lithium cells are used to support continuous ECG acquiring and storage for up to 15 days. Meanwhile, the wearable electrodes avoid the pains and possible risks in implanting. Besides, the mini size of the system makes long wearing possible for patients and meets the needs of long-term dynamic monitoring and mass storage requirements.

  9. Organic photovoltaics: elucidating the ultra-fast exciton dissociation mechanism in disordered materials.

    PubMed

    Heitzer, Henry M; Savoie, Brett M; Marks, Tobin J; Ratner, Mark A

    2014-07-14

    Organic photovoltaics (OPVs) offer the opportunity for cheap, lightweight and mass-producible devices. However, an incomplete understanding of the charge generation process, in particular the timescale of dynamics and role of exciton diffusion, has slowed further progress in the field. We report a new Kinetic Monte Carlo model for the exciton dissociation mechanism in OPVs that addresses the origin of ultra-fast (<1 ps) dissociation by incorporating exciton delocalization. The model reproduces experimental results, such as the diminished rapid dissociation with increasing domain size, and also lends insight into the interplay between mixed domains, domain geometry, and exciton delocalization. Additionally, the model addresses the recent dispute on the origin of ultra-fast exciton dissociation by comparing the effects of exciton delocalization and impure domains on the photo-dynamics.This model provides insight into exciton dynamics that can advance our understanding of OPV structure-function relationships. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Magnetic Resonance Relaxometry at Low and Ultra low Fields.

    PubMed

    Volegov, P; Flynn, M; Kraus, R; Magnelind, P; Matlashov, A; Nath, P; Owens, T; Sandin, H; Savukov, I; Schultz, L; Urbaitis, A; Zotev, V; Espy, M

    2010-01-01

    Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) are ubiquitous tools in science and medicine. NMR provides powerful probes of local and macromolecular chemical structure and dynamics. Recently it has become possible and practical to perform MR at very low fields (from 1 μT to 1 mT), the so-called ultra-low field (ULF) regime. Pulsed pre-polarizing fields greatly enhance the signal strength and allow flexibility in signal acquisition sequences. Improvements in SQUID sensor technology allow ultra-sensitive detection in a pulsed field environment.In this regime the proton Larmor frequencies (1 Hz - 100 kHz) of ULF MR overlap (on a time scale of 10 μs to 100 ms) with "slow" molecular dynamic processes such as diffusion, intra-molecular motion, chemical reactions, and biological processes such as protein folding, catalysis and ligand binding. The frequency dependence of relaxation at ultra-low fields may provide a probe for biomolecular dynamics on the millisecond timescale (protein folding and aggregation, conformational motions of enzymes, binding and structural fluctuations of coupled domains in allosteric mechanisms) relevant to host-pathogen interactions, biofuels, and biomediation. Also this resonance-enhanced coupling at ULF can greatly enhance contrast in medical applications of ULF-MRI resulting in better diagnostic techniques.We have developed a number of instruments and techniques to study relaxation vs. frequency at the ULF regime. Details of the techniques and results are presented.Ultra-low field methods are already being applied at LANL in brain imaging, and detection of liquid explosives at airports. However, the potential power of ultra-low field MR remains to be fully exploited.

  11. Dynamic hyporheic exchange at intermediate timescales: testing the relative importance of evapotranspiration and flood pulses

    USGS Publications Warehouse

    Larsen, Laurel G.; Harvey, Judson W.; Maglio, Morgan M.

    2014-01-01

    Hyporheic fluxes influence ecological processes across a continuum of timescales. However, few studies have been able to characterize hyporheic fluxes and residence time distributions (RTDs) over timescales of days to years, during which evapotranspiration (ET) and seasonal flood pulses create unsteady forcing. Here we present a data-driven, particle-tracking piston model that characterizes hyporheic fluxes and RTDs based on measured vertical head differences. We used the model to test the relative influence of ET and seasonal flood pulses in the Everglades (FL, USA), in a manner applicable to other low-energy floodplains or broad, shallow streams. We found that over the multiyear timescale, flood pulses that drive relatively deep (∼1 m) flow paths had the dominant influence on hyporheic fluxes and residence times but that ET effects were discernible at shorter timescales (weeks to months) as a break in RTDs. Cumulative RTDs on either side of the break were generally well represented by lognormal functions, except for when ET was strong and none of the standard distributions applied to the shorter timescale. At the monthly timescale, ET increased hyporheic fluxes by 1–2 orders of magnitude; it also decreased 6 year mean residence times by 53–87%. Long, slow flow paths driven by flood pulses increased 6 year hyporheic fluxes by another 1–2 orders of magnitude, to a level comparable to that induced over the short term by shear flow in streams. Results suggest that models of intermediate-timescale processes should include at least two-storage zones with different RTDs, and that supporting field data collection occur over 3–4 years.

  12. Fabrication et applications des reseaux de Bragg ultra-longs

    NASA Astrophysics Data System (ADS)

    Gagne, Mathieu

    This thesis presents the principal accomplishments realized during the PhD project. The thesis is presented by publication format and is a collection of four published articles having fiber Bragg gratings as a central theme. First achieved in 1978, UV writing of fiber Bragg gratings is nowadays a common and mature technology being present in both industry and academia. The property of reflecting light guided by optical fibers lead to diverse applications in telecommunication, lasers as well as several types of sensors. The conventional fabrication technique is generally based on the use of generally expensive phase masks which determine the obtained characteristics of the fiber Bragg grating. The fiber being photosensitive at those wavelengths, a periodic pattern can be written into it. The maximal length, the period, the chirp, the index contrast and the apodisation are all characteristics that depend on the phase mask. The first objective of the research project is to be able to go beyond this strong dependance on the phase mask without deteriorating grating quality. This is what really sets apart the technique presented in this thesis from other long fiber Bragg grating fabrication techniques available in the literature. The fundamental approach to obtain ultra long fiber Bragg gratings of arbitrary profile is to replace the scheme of scanning a UV beam across a phase mask to expose a fixed fiber by a scheme where the UV beam and phase mask are fixed and where the fiber is moving instead. To obtain a periodic index variation, the interference pattern itself must be synchronized with the moving fiber. Two variations of this scheme were implanted: the first one using electro-optical phase modulator placed in each arm of a Talbot interferometer and the second one using a phase mask mounted on a piezo electric actuator. A new scheme that imparts fine movements of the interferometer is also implemented for the first time and showed to be essential to achieve high

  13. Contributions of adaptation currents to dynamic spike threshold on slow timescales: Biophysical insights from conductance-based models

    NASA Astrophysics Data System (ADS)

    Yi, Guosheng; Wang, Jiang; Wei, Xile; Deng, Bin; Li, Huiyan; Che, Yanqiu

    2017-06-01

    Spike-frequency adaptation (SFA) mediated by various adaptation currents, such as voltage-gated K+ current (IM), Ca2+-gated K+ current (IAHP), or Na+-activated K+ current (IKNa), exists in many types of neurons, which has been shown to effectively shape their information transmission properties on slow timescales. Here we use conductance-based models to investigate how the activation of three adaptation currents regulates the threshold voltage for action potential (AP) initiation during the course of SFA. It is observed that the spike threshold gets depolarized and the rate of membrane depolarization (dV/dt) preceding AP is reduced as adaptation currents reduce firing rate. It is indicated that the presence of inhibitory adaptation currents enables the neuron to generate a dynamic threshold inversely correlated with preceding dV/dt on slower timescales than fast dynamics of AP generation. By analyzing the interactions of ionic currents at subthreshold potentials, we find that the activation of adaptation currents increase the outward level of net membrane current prior to AP initiation, which antagonizes inward Na+ to result in a depolarized threshold and lower dV/dt from one AP to the next. Our simulations demonstrate that the threshold dynamics on slow timescales is a secondary effect caused by the activation of adaptation currents. These findings have provided a biophysical interpretation of the relationship between adaptation currents and spike threshold.

  14. Ultra-thin enhanced-absorption long-wave infrared detectors

    NASA Astrophysics Data System (ADS)

    Wang, Shaohua; Yoon, Narae; Kamboj, Abhilasha; Petluru, Priyanka; Zheng, Wanhua; Wasserman, Daniel

    2018-02-01

    We propose an architecture for enhanced absorption in ultra-thin strained layer superlattice detectors utilizing a hybrid optical cavity design. Our detector architecture utilizes a designer-metal doped semiconductor ground plane beneath the ultra-subwavelength thickness long-wavelength infrared absorber material, upon which we pattern metallic antenna structures. We demonstrate the potential for near 50% detector absorption in absorber layers with thicknesses of approximately λ0/50, using realistic material parameters. We investigate detector absorption as a function of wavelength and incidence angle, as well as detector geometry. The proposed device architecture offers the potential for high efficiency detectors with minimal growth costs and relaxed design parameters.

  15. A Two-Timescale Discretization Scheme for Collocation

    NASA Technical Reports Server (NTRS)

    Desai, Prasun; Conway, Bruce A.

    2004-01-01

    The development of a two-timescale discretization scheme for collocation is presented. This scheme allows a larger discretization to be utilized for smoothly varying state variables and a second finer discretization to be utilized for state variables having higher frequency dynamics. As such. the discretization scheme can be tailored to the dynamics of the particular state variables. In so doing. the size of the overall Nonlinear Programming (NLP) problem can be reduced significantly. Two two-timescale discretization architecture schemes are described. Comparison of results between the two-timescale method and conventional collocation show very good agreement. Differences of less than 0.5 percent are observed. Consequently. a significant reduction (by two-thirds) in the number of NLP parameters and iterations required for convergence can be achieved without sacrificing solution accuracy.

  16. Ultra-Long-Distance Hybrid BOTDA/Ф-OTDR

    PubMed Central

    Fu, Yun; Zhu, Richeng; Xue, Naitian; Lu, Chongyu; Zhang, Bin; Yang, Le; Atubga, David; Rao, Yunjiang

    2018-01-01

    In the distributed optical fiber sensing (DOFS) domain, simultaneous measurement of vibration and temperature/strain based on Rayleigh scattering and Brillouin scattering in fiber could have wide applications. However, there are certain challenges for the case of ultra-long sensing range, including the interplay of different scattering mechanisms, the interaction of two types of sensing signals, and the competition of pump power. In this paper, a hybrid DOFS system, which can simultaneously measure temperature/strain and vibration over 150 km, is elaborately designed via integrating the Brillouin optical time-domain analyzer (BOTDA) and phase-sensitive optical time-domain reflectometry (Ф-OTDR). Distributed Raman and Brillouin amplifications, frequency division multiplexing (FDM), wavelength division multiplexing (WDM), and time division multiplexing (TDM) are delicately fused to accommodate ultra-long-distance BOTDA and Ф-OTDR. Consequently, the sensing range of the hybrid system is 150.62 km, and the spatial resolution of BOTDA and Ф-OTDR are 9 m and 30 m, respectively. The measurement uncertainty of the BOTDA is ± 0.82 MHz. To the best of our knowledge, this is the first time that such hybrid DOFS is realized with a hundred-kilometer length scale. PMID:29587407

  17. Probing ultra-fast processes with high dynamic range at 4th-generation light sources: Arrival time and intensity binning at unprecedented repetition rates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kovalev, S.; Green, B.; Golz, T.

    Here, understanding dynamics on ultrafast timescales enables unique and new insights into important processes in the materials and life sciences. In this respect, the fundamental pump-probe approach based on ultra-short photon pulses aims at the creation of stroboscopic movies. Performing such experiments at one of the many recently established accelerator-based 4th-generation light sources such as free-electron lasers or superradiant THz sources allows an enormous widening of the accessible parameter space for the excitation and/or probing light pulses. Compared to table-top devices, critical issues of this type of experiment are fluctuations of the timing between the accelerator and external laser systemsmore » and intensity instabilities of the accelerator-based photon sources. Existing solutions have so far been only demonstrated at low repetition rates and/or achieved a limited dynamic range in comparison to table-top experiments, while the 4th generation of accelerator-based light sources is based on superconducting radio-frequency technology, which enables operation at MHz or even GHz repetition rates. In this article, we present the successful demonstration of ultra-fast accelerator-laser pump-probe experiments performed at an unprecedentedly high repetition rate in the few-hundred-kHz regime and with a currently achievable optimal time resolution of 13 fs (rms). Our scheme, based on the pulse-resolved detection of multiple beam parameters relevant for the experiment, allows us to achieve an excellent sensitivity in real-world ultra-fast experiments, as demonstrated for the example of THz-field-driven coherent spin precession.« less

  18. Probing ultra-fast processes with high dynamic range at 4th-generation light sources: Arrival time and intensity binning at unprecedented repetition rates.

    PubMed

    Kovalev, S; Green, B; Golz, T; Maehrlein, S; Stojanovic, N; Fisher, A S; Kampfrath, T; Gensch, M

    2017-03-01

    Understanding dynamics on ultrafast timescales enables unique and new insights into important processes in the materials and life sciences. In this respect, the fundamental pump-probe approach based on ultra-short photon pulses aims at the creation of stroboscopic movies. Performing such experiments at one of the many recently established accelerator-based 4th-generation light sources such as free-electron lasers or superradiant THz sources allows an enormous widening of the accessible parameter space for the excitation and/or probing light pulses. Compared to table-top devices, critical issues of this type of experiment are fluctuations of the timing between the accelerator and external laser systems and intensity instabilities of the accelerator-based photon sources. Existing solutions have so far been only demonstrated at low repetition rates and/or achieved a limited dynamic range in comparison to table-top experiments, while the 4th generation of accelerator-based light sources is based on superconducting radio-frequency technology, which enables operation at MHz or even GHz repetition rates. In this article, we present the successful demonstration of ultra-fast accelerator-laser pump-probe experiments performed at an unprecedentedly high repetition rate in the few-hundred-kHz regime and with a currently achievable optimal time resolution of 13 fs (rms). Our scheme, based on the pulse-resolved detection of multiple beam parameters relevant for the experiment, allows us to achieve an excellent sensitivity in real-world ultra-fast experiments, as demonstrated for the example of THz-field-driven coherent spin precession.

  19. Probing ultra-fast processes with high dynamic range at 4th-generation light sources: Arrival time and intensity binning at unprecedented repetition rates

    DOE PAGES

    Kovalev, S.; Green, B.; Golz, T.; ...

    2017-03-06

    Here, understanding dynamics on ultrafast timescales enables unique and new insights into important processes in the materials and life sciences. In this respect, the fundamental pump-probe approach based on ultra-short photon pulses aims at the creation of stroboscopic movies. Performing such experiments at one of the many recently established accelerator-based 4th-generation light sources such as free-electron lasers or superradiant THz sources allows an enormous widening of the accessible parameter space for the excitation and/or probing light pulses. Compared to table-top devices, critical issues of this type of experiment are fluctuations of the timing between the accelerator and external laser systemsmore » and intensity instabilities of the accelerator-based photon sources. Existing solutions have so far been only demonstrated at low repetition rates and/or achieved a limited dynamic range in comparison to table-top experiments, while the 4th generation of accelerator-based light sources is based on superconducting radio-frequency technology, which enables operation at MHz or even GHz repetition rates. In this article, we present the successful demonstration of ultra-fast accelerator-laser pump-probe experiments performed at an unprecedentedly high repetition rate in the few-hundred-kHz regime and with a currently achievable optimal time resolution of 13 fs (rms). Our scheme, based on the pulse-resolved detection of multiple beam parameters relevant for the experiment, allows us to achieve an excellent sensitivity in real-world ultra-fast experiments, as demonstrated for the example of THz-field-driven coherent spin precession.« less

  20. Timescales of Coherent Dynamics in the Light Harvesting Complex 2 (LH2) of Rhodobacter sphaeroides.

    PubMed

    Fidler, Andrew F; Singh, Ved P; Long, Phillip D; Dahlberg, Peter D; Engel, Gregory S

    2013-05-02

    The initial dynamics of energy transfer in the light harvesting complex 2 from Rhodobacter sphaeroides were investigated with polarization controlled two-dimensional spectroscopy. This method allows only the coherent electronic motions to be observed revealing the timescale of dephasing among the excited states. We observe persistent coherence among all states and assign ensemble dephasing rates for the various coherences. A simple model is utilized to connect the spectroscopic transitions to the molecular structure, allowing us to distinguish coherences between the two rings of chromophores and coherences within the rings. We also compare dephasing rates between excited states to dephasing rates between the ground and excited states, revealing that the coherences between excited states dephase on a slower timescale than coherences between the ground and excited states.

  1. Reorientation Timescales and Pattern Dynamics for Titan's Dunes: Does the Tail Wag the Dog or the Dragon?

    NASA Astrophysics Data System (ADS)

    Hayes, A. G.; Ewing, R. C.; Cassini Radar Science Team, T.

    2011-12-01

    Fields of bedform patterns persist across many orders of magnitude, from cm-scale sub-aqueous current ripples to km-scale aeolian dunes, and form with surprisingly little difference in expression despite a range of formative environments. Because of the remarkable similarity between and among patterns, extracting information about climate and environment from these patterns is a challenge. For example, crest orientation is not diagnostic of a particular flow regime; similar patterns form under many different flow configurations. On Titan, these challenges have played out with many attempts to reconcile dune-field patterns with modeled and expected wind regimes. We propose that thinking about the change in dune orientation, rather than the orientation itself, can provide new insights on the long-term stability of the dune-field patterns and the formative wind regime. In this work, we apply the re-orientation model presented by Werner and Kocurek [Geology, 1997] to the equatorial dune fields of Titan. We measure variations in pattern parameters (crest spacing, crest length and defect density, which is the number of defect pairs per total crest length) both within and between Titan's dune fields to describe pattern maturity and identify areas where changes in dune orientation are likely to occur (or may already be occurring). Measured defect densities are similar to Earth's largest linear dune fields, such as the Namib Sand Sea and the Simpson Desert. We use measured defect densities in the Werner and Kocurek model to estimate crestline reorientation rates. We find reorientation timescales varying from ten to a hundred thousand times the average migration timescale (time to migrate a bedform one meter, ~1 Titan year according to Tokano (Aeolian Research, 2010)). Well organized patterns have the longest reorientation time scales (~10^5 migration timescales), while the topographically or spatially isolated patches of dunes show the shortest reorientation times (~10

  2. Ultra-long high-sensitivity Φ-OTDR for high spatial resolution intrusion detection of pipelines.

    PubMed

    Peng, Fei; Wu, Han; Jia, Xin-Hong; Rao, Yun-Jiang; Wang, Zi-Nan; Peng, Zheng-Pu

    2014-06-02

    An ultra-long phase-sensitive optical time domain reflectometry (Φ-OTDR) that can achieve high-sensitivity intrusion detection over 131.5km fiber with high spatial resolution of 8m is presented, which is the longest Φ-OTDR reported to date, to the best of our knowledge. It is found that the combination of distributed Raman amplification with heterodyne detection can extend the sensing distance and enhances the sensitivity substantially, leading to the realization of ultra-long Φ-OTDR with high sensitivity and spatial resolution. Furthermore, the feasibility of applying such an ultra-long Φ-OTDR to pipeline security monitoring is demonstrated and the features of intrusion signal can be extracted with improved SNR by using the wavelet detrending/denoising method proposed.

  3. GRB 080407: An Ultra-long Burst Discovered by the IPN

    NASA Technical Reports Server (NTRS)

    Cummings, J; Barthelmy, S.; Gehrels, N.; Krimm, H.; Palmer, D.; Palshin, V.; Hurley, K.; Goldsten, J.; Mitrofanov, I. G.; Boynton, W.; hide

    2012-01-01

    We present observations of the extremely long GRB 080704 obtained with the instruments of the Interplanetary Network (IPN). The observations reveal two distinct emission episodes, separated by a approx.1500 s long period of quiescence. The total burst duration is about 2100 s. We compare the temporal and spectral characteristics of this burst with those obtained for other ultra-long GRBs and discuss these characteristics in the context of different models.

  4. Persistence and memory timescales in root-zone soil moisture dynamics

    Treesearch

    Khaled Ghannam; Taro Nakai; Athanasios Paschalis; Andrew C. Oishi; Ayumi Kotani; Yasunori Igarashi; Tomo' omi Kumagai; Gabriel G. Katul

    2016-01-01

    The memory timescale that characterizes root-zone soil moisture remains the dominant measure in seasonal forecasts of land-climate interactions. This memory is a quasi-deterministic timescale associated with the losses (e.g., evapotranspiration) from the soil column and is often interpreted as persistence in soil moisture states. Persistence, however,...

  5. Complex Processes from Dynamical Architectures with Time-Scale Hierarchy

    PubMed Central

    Perdikis, Dionysios; Huys, Raoul; Jirsa, Viktor

    2011-01-01

    The idea that complex motor, perceptual, and cognitive behaviors are composed of smaller units, which are somehow brought into a meaningful relation, permeates the biological and life sciences. However, no principled framework defining the constituent elementary processes has been developed to this date. Consequently, functional configurations (or architectures) relating elementary processes and external influences are mostly piecemeal formulations suitable to particular instances only. Here, we develop a general dynamical framework for distinct functional architectures characterized by the time-scale separation of their constituents and evaluate their efficiency. Thereto, we build on the (phase) flow of a system, which prescribes the temporal evolution of its state variables. The phase flow topology allows for the unambiguous classification of qualitatively distinct processes, which we consider to represent the functional units or modes within the dynamical architecture. Using the example of a composite movement we illustrate how different architectures can be characterized by their degree of time scale separation between the internal elements of the architecture (i.e. the functional modes) and external interventions. We reveal a tradeoff of the interactions between internal and external influences, which offers a theoretical justification for the efficient composition of complex processes out of non-trivial elementary processes or functional modes. PMID:21347363

  6. Ultra-Broadband Two-Dimensional Electronic Spectroscopy and Pump-Probe Microscopy of Molecular Systems

    NASA Astrophysics Data System (ADS)

    Spokoyny, Boris M.

    Ultrafast spectroscopy offers an unprecedented view on the dynamic nature of chemical reactions. From charge transfer in semiconductors to folding and isomerization of proteins, these all important processes can now be monitored and in some instances even controlled on real, physical timescales. One of the biggest challenges of ultrafast science is the incredible energetic complexity of most systems. It is not uncommon to encounter macromolecules or materials with absorption spectra spanning significant portions of the visible spectrum. Monitoring a multitude of electronic and vibrational transitions, all dynamically interacting with each other on femtosecond timescales poses a truly daunting experimental task. The first part of this thesis deals with the development of a novel Two-Dimensional Electronic Spectroscopy (2DES) and its associated, advanced detection methodologies. Owing to its ultra-broadband implementation, this technique enables us to monitor femtosecond chemical dynamics that span the energetic landscape of the entire visible spectrum. In order to demonstrate the utility of our method, we apply it to two laser dye molecules, IR-144 and Cresyl Violet. Variation of photophysical properties on a microscopic scale in either man-made or naturally occurring systems can have profound implications on how we understand their macroscopic properties. Recently, inorganic hybrid perovskites have been tapped as the next generation solar energy harvesting materials. Their remarkable properties include low exciton binding energy, low exciton recombination rates and long carrier diffusion lengths. Nevertheless, considerable variability in device properties made with nearly identical preparation methods has puzzled the community. In the second part of this thesis we use non-linear pump probe microscopy to study the heterogeneous nature of femtosecond carrier dynamics in thin film perovskites. We show that the local morphology of the perovskite thin films has a

  7. An exotic long-term pattern in stock price dynamics.

    PubMed

    Wei, Jianrong; Huang, Jiping

    2012-01-01

    To accurately predict the movement of stock prices is always of both academic importance and practical value. So far, a lot of research has been reported to help understand the behavior of stock prices. However, some of the existing theories tend to render us the belief that the time series of stock prices are unpredictable on a long-term timescale. The question arises whether the long-term predictability exists in stock price dynamics. In this work, we analyze the price reversals in the US stock market and the Chinese stock market on the basis of a renormalization method. The price reversals are divided into two types: retracements (the downward trends after upward trends) and rebounds (the upward trends after downward trends), of which the intensities are described by dimensionless quantities, R(t) and R(b), respectively. We reveal that for both mature and emerging markets, the distribution of either retracements R(t) or rebounds R(b) shows two characteristic values, 0.335 and 0.665, both of which are robust over the long term. The methodology presented here provides a way to quantify the stock price reversals. Our findings strongly support the existence of the long-term predictability in stock price dynamics, and may offer a hint on how to predict the long-term movement of stock prices.

  8. Explaining the Diverse Response of the Ultra-relativistic Van Allen Radiation Belt to Solar Wind Forcing

    NASA Astrophysics Data System (ADS)

    Mann, I. R.; Ozeke, L.; Murphy, K. R.; Claudepierre, S. G.; Rae, J.; Milling, D. K.; Kale, A.; Baker, D. N.

    2017-12-01

    The NASA Van Allen Probes have opened a new window on the dynamics of ultra-relativistic electrons in the Van Allen radiation belts. Under different solar wind forcing the outer belt is seen to respond in a variety of apparently diverse and sometimes remarkable ways. For example, sometimes a third radiation belt is carved out (e.g., September 2012), or the belts can remain depleted for 10 days or more (September 2014). More usually there is a sequential response of a strong and sometimes rapid depletion followed by a re-energization, the latter increasing outer belt electron flux by orders of magnitude on hour timescales during some of the strongest storms of this solar cycle (e.g., March 2013, March 2015). Such dynamics also appear to be often bounded at low-L by an apparently impenetrable barrier at L 2.8 through which ultra-relativistic electrons do not penetrate. Many studies in the Van Allen Probes era have sought explanations for these apparently diverse features, often incorporating the effects from multiple plasma waves. In contrast, we show how this apparently diverse behaviour can instead be explained by one dominant process: ULF wave radial transport. Once ULF wave transport rates are accurately specified by observations, and coupled to the dynamical variation of the outer boundary condition at the edge of the outer belt, the observed diverse responses can all be explained. However, in order to get good agreement with observations, the modeling reveals the importance of still currently unexplained very fast loss in the main phase which results in an almost total extinction of the belts and decouples pre- and post-storm ultra-relativistic electron flux on hour timescales. Similarly, varying plasmasheet source populations are seen to be of critical importance such that near-tail dynamics play a crucial role in Van Allen belt dynamics. Nonetheless, simple models incorporating accurate transport rates derived directly from ULF wave measurements are shown to

  9. Detection of timescales in evolving complex systems

    PubMed Central

    Darst, Richard K.; Granell, Clara; Arenas, Alex; Gómez, Sergio; Saramäki, Jari; Fortunato, Santo

    2016-01-01

    Most complex systems are intrinsically dynamic in nature. The evolution of a dynamic complex system is typically represented as a sequence of snapshots, where each snapshot describes the configuration of the system at a particular instant of time. This is often done by using constant intervals but a better approach would be to define dynamic intervals that match the evolution of the system’s configuration. To this end, we propose a method that aims at detecting evolutionary changes in the configuration of a complex system, and generates intervals accordingly. We show that evolutionary timescales can be identified by looking for peaks in the similarity between the sets of events on consecutive time intervals of data. Tests on simple toy models reveal that the technique is able to detect evolutionary timescales of time-varying data both when the evolution is smooth as well as when it changes sharply. This is further corroborated by analyses of several real datasets. Our method is scalable to extremely large datasets and is computationally efficient. This allows a quick, parameter-free detection of multiple timescales in the evolution of a complex system. PMID:28004820

  10. Dynamics of Wetting of Ultra Hydrophobic Surfaces

    NASA Astrophysics Data System (ADS)

    Mohammad Karim, Alireza; Kim, Jeong-Hyun; Rothstein, Jonathan; Kavehpour, Pirouz; Mechanical and Industrial Engineering, University of Massachusetts, Amherst Collaboration

    2013-11-01

    Controlling the surface wettability of hydrophobic and super hydrophobic surfaces has extensive industrial applications ranging from coating, painting and printing technology and waterproof clothing to efficiency increase in power and water plants. This requires enhancing the knowledge about the dynamics of wetting on these hydrophobic surfaces. We have done experimental investigation on the dynamics of wetting on hydrophobic surfaces by looking deeply in to the dependency of the dynamic contact angles both advancing and receding on the velocity of the three-phase boundary (Solid/Liquid/Gas interface) using the Wilhelmy plate method with different ultra-hydrophobic surfaces. Several fluids with different surface tension and viscosity are used to study the effect of physical properties of liquids on the governing laws.

  11. Long-time atomistic simulations with the Parallel Replica Dynamics method

    NASA Astrophysics Data System (ADS)

    Perez, Danny

    Molecular Dynamics (MD) -- the numerical integration of atomistic equations of motion -- is a workhorse of computational materials science. Indeed, MD can in principle be used to obtain any thermodynamic or kinetic quantity, without introducing any approximation or assumptions beyond the adequacy of the interaction potential. It is therefore an extremely powerful and flexible tool to study materials with atomistic spatio-temporal resolution. These enviable qualities however come at a steep computational price, hence limiting the system sizes and simulation times that can be achieved in practice. While the size limitation can be efficiently addressed with massively parallel implementations of MD based on spatial decomposition strategies, allowing for the simulation of trillions of atoms, the same approach usually cannot extend the timescales much beyond microseconds. In this article, we discuss an alternative parallel-in-time approach, the Parallel Replica Dynamics (ParRep) method, that aims at addressing the timescale limitation of MD for systems that evolve through rare state-to-state transitions. We review the formal underpinnings of the method and demonstrate that it can provide arbitrarily accurate results for any definition of the states. When an adequate definition of the states is available, ParRep can simulate trajectories with a parallel speedup approaching the number of replicas used. We demonstrate the usefulness of ParRep by presenting different examples of materials simulations where access to long timescales was essential to access the physical regime of interest and discuss practical considerations that must be addressed to carry out these simulations. Work supported by the United States Department of Energy (U.S. DOE), Office of Science, Office of Basic Energy Sciences, Materials Sciences and Engineering Division.

  12. A sensitivity study of fast outlet glaciers to short timescale cyclical perturbations

    NASA Astrophysics Data System (ADS)

    Aykutlug, E.; Dupont, T. K.

    2015-01-01

    The dynamic response of outlet glaciers on short (annual to decadal) timescales is affected by various external forcings, such as basal or oceanic conditions. Understanding the sensitivity of the dynamic response to such forcings can help assess more accurate ice volume projections. In this work, we investigate the spatiotemporal sensitivity of outlet glaciers to fast cyclical forcings using a one-dimensional depth and width-averaged heuristic model. Our results indicate that even on such short timescales, nonlinearities in ice dynamics may lead to an asymmetric response, despite the forcing functions being symmetric around each reference value. Results also show that such short-timescale effects become more pronounced as glaciers become closer to flotation. While being qualitatively similar for both downsloping and upsloping bed geometries, the results indicate higher sensitivity for upsloping ("West Antarctica-like") beds. The range in asymmetric response for different configurations motivate parameterizing or including short-timescale effects in models while investigating the dynamic behavior of outlet glaciers.

  13. Explaining the dynamics of the ultra-relativistic third Van Allen radiation belt

    DOE PAGES

    Mann, I. R.; Ozeke, L. G.; Murphy, K. R.; ...

    2016-06-20

    Since the discovery of the Van Allen radiation belts over 50 years ago, an explanation for their complete dynamics has remained elusive. Especially challenging is understanding the recently discovered ultra-relativistic third electron radiation belt. Current theory asserts that loss in the heart of the outer belt, essential to the formation of the third belt, must be controlled by high-frequency plasma wave–particle scattering into the atmosphere, via whistler mode chorus, plasmaspheric hiss, or electromagnetic ion cyclotron waves. However, this has failed to accurately reproduce the third belt. In this paper, using a data-driven, time-dependent specification of ultra-low-frequency (ULF) waves we showmore » for the first time how the third radiation belt is established as a simple, elegant consequence of storm-time extremely fast outward ULF wave transport. High-frequency wave–particle scattering loss into the atmosphere is not needed in this case. Finally, when rapid ULF wave transport coupled to a dynamic boundary is accurately specified, the sensitive dynamics controlling the enigmatic ultra-relativistic third radiation belt are naturally explained.« less

  14. Explaining the dynamics of the ultra-relativistic third Van Allen radiation belt

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mann, I. R.; Ozeke, L. G.; Murphy, K. R.

    Since the discovery of the Van Allen radiation belts over 50 years ago, an explanation for their complete dynamics has remained elusive. Especially challenging is understanding the recently discovered ultra-relativistic third electron radiation belt. Current theory asserts that loss in the heart of the outer belt, essential to the formation of the third belt, must be controlled by high-frequency plasma wave–particle scattering into the atmosphere, via whistler mode chorus, plasmaspheric hiss, or electromagnetic ion cyclotron waves. However, this has failed to accurately reproduce the third belt. In this paper, using a data-driven, time-dependent specification of ultra-low-frequency (ULF) waves we showmore » for the first time how the third radiation belt is established as a simple, elegant consequence of storm-time extremely fast outward ULF wave transport. High-frequency wave–particle scattering loss into the atmosphere is not needed in this case. Finally, when rapid ULF wave transport coupled to a dynamic boundary is accurately specified, the sensitive dynamics controlling the enigmatic ultra-relativistic third radiation belt are naturally explained.« less

  15. STARD6 on steroids: solution structure, multiple timescale backbone dynamics and ligand binding mechanism

    NASA Astrophysics Data System (ADS)

    Létourneau, Danny; Bédard, Mikaël; Cabana, Jérôme; Lefebvre, Andrée; Lehoux, Jean-Guy; Lavigne, Pierre

    2016-06-01

    START domain proteins are conserved α/β helix-grip fold that play a role in the non-vesicular and intracellular transport of lipids and sterols. The mechanism and conformational changes permitting the entry of the ligand into their buried binding sites is not well understood. Moreover, their functions and the identification of cognate ligands is still an active area of research. Here, we report the solution structure of STARD6 and the characterization of its backbone dynamics on multiple time-scales through 15N spin-relaxation and amide exchange studies. We reveal for the first time the presence of concerted fluctuations in the Ω1 loop and the C-terminal helix on the microsecond-millisecond time-scale that allows for the opening of the binding site and ligand entry. We also report that STARD6 binds specifically testosterone. Our work represents a milestone for the study of ligand binding mechanism by other START domains and the elucidation of the biological function of STARD6.

  16. Multiscale molecular dynamics simulations of rotary motor proteins.

    PubMed

    Ekimoto, Toru; Ikeguchi, Mitsunori

    2018-04-01

    Protein functions require specific structures frequently coupled with conformational changes. The scale of the structural dynamics of proteins spans from the atomic to the molecular level. Theoretically, all-atom molecular dynamics (MD) simulation is a powerful tool to investigate protein dynamics because the MD simulation is capable of capturing conformational changes obeying the intrinsically structural features. However, to study long-timescale dynamics, efficient sampling techniques and coarse-grained (CG) approaches coupled with all-atom MD simulations, termed multiscale MD simulations, are required to overcome the timescale limitation in all-atom MD simulations. Here, we review two examples of rotary motor proteins examined using free energy landscape (FEL) analysis and CG-MD simulations. In the FEL analysis, FEL is calculated as a function of reaction coordinates, and the long-timescale dynamics corresponding to conformational changes is described as transitions on the FEL surface. Another approach is the utilization of the CG model, in which the CG parameters are tuned using the fluctuation matching methodology with all-atom MD simulations. The long-timespan dynamics is then elucidated straightforwardly by using CG-MD simulations.

  17. Heat transfer nanofluid based on curly ultra-long multi-wall carbon nanotubes

    NASA Astrophysics Data System (ADS)

    Boncel, Sławomir; Zniszczoł, Aurelia; Pawlyta, Mirosława; Labisz, Krzysztof; Dzido, Grzegorz

    2018-02-01

    The main challenge in the use of multi-wall carbon nanotube (MWCNT) as key components of nanofluids is to transfer excellent thermal properties from individual nanotubes into the bulk systems. We present studies on the performance of heat transfer nanofluids based on ultra-long ( 2 mm), curly MWCNTs - in the background of various other nanoC-sp2, i.e. oxidized MWCNTs, commercially available Nanocyl™ MWCNTs and spherical carbon nanoparticles (SCNs). The nanofluids prepared via ultrasonication from water and propylene glycol were studied in terms of heat conductivity and heat transfer in a scaled up thermal circuit containing a copper helical heat exchanger. Ultra-long curly MWCNT (1 wt.%) nanofluids (stabilized with Gum Arabic in water) emerged as the most thermally conducting ones with a 23-30%- and 39%-enhancement as compared to the base-fluids for water and propylene glycol, respectively. For turbulent flows ( Re = 8000-11,000), the increase of heat transfer coefficient for the over-months stable 1 wt.% ultra-long MWCNT nanofluid was found as high as >100%. The findings allow to confirm that longer MWCNTs are promising solid components in nanofluids and hence to predict their broader application in heat transfer media.

  18. Six-Degree-of-Freedom Trajectory Optimization Utilizing a Two-Timescale Collocation Architecture

    NASA Technical Reports Server (NTRS)

    Desai, Prasun N.; Conway, Bruce A.

    2005-01-01

    Six-degree-of-freedom (6DOF) trajectory optimization of a reentry vehicle is solved using a two-timescale collocation methodology. This class of 6DOF trajectory problems are characterized by two distinct timescales in their governing equations, where a subset of the states have high-frequency dynamics (the rotational equations of motion) while the remaining states (the translational equations of motion) vary comparatively slowly. With conventional collocation methods, the 6DOF problem size becomes extraordinarily large and difficult to solve. Utilizing the two-timescale collocation architecture, the problem size is reduced significantly. The converged solution shows a realistic landing profile and captures the appropriate high-frequency rotational dynamics. A large reduction in the overall problem size (by 55%) is attained with the two-timescale architecture as compared to the conventional single-timescale collocation method. Consequently, optimum 6DOF trajectory problems can now be solved efficiently using collocation, which was not previously possible for a system with two distinct timescales in the governing states.

  19. Dynamics of glass-forming liquids. XV. Dynamical features of molecular liquids that form ultra-stable glasses by vapor deposition

    NASA Astrophysics Data System (ADS)

    Chen, Zhen; Richert, Ranko

    2011-09-01

    The dielectric relaxation behavior of ethylbenzene (EBZ) in its viscous regime is measured, and the glass transition temperature (Tg = 116 K) as well as fragility (m = 98) are determined. While the Tg of EBZ from this work is consistent with earlier results, the fragility is found much higher than what has been assumed previously. Literature data is supplemented by the present results on EBZ to compile the dynamic behavior of those glass formers that are known to form ultra-stable glasses by vapor deposition. These dynamics are contrasted with those of ethylcyclohexane, a glass former for which a comparable vapor deposition failed to produce an equally stable glassy state. In a graph that linearizes Vogel-Fulcher-Tammann behavior, i.e., the derivative of -logτ with respect to T/Tg raised to the power of -1/2 versus T/Tg, all ultra-stable glass formers fall onto one master curve in a wide temperature range, while ethylcyclohexane deviates for T ≫ Tg. This result suggests that ultra-stable glass formers share common behavior regarding the dynamics of their supercooled liquid state if scaled to their respective Tg values, and that fragility and related features are linked to the ability to form ultra-stable materials.

  20. A very luminous magnetar-powered supernova associated with an ultra-long γ-ray burst.

    PubMed

    Greiner, Jochen; Mazzali, Paolo A; Kann, D Alexander; Krühler, Thomas; Pian, Elena; Prentice, Simon; Olivares E, Felipe; Rossi, Andrea; Klose, Sylvio; Taubenberger, Stefan; Knust, Fabian; Afonso, Paulo M J; Ashall, Chris; Bolmer, Jan; Delvaux, Corentin; Diehl, Roland; Elliott, Jonathan; Filgas, Robert; Fynbo, Johan P U; Graham, John F; Guelbenzu, Ana Nicuesa; Kobayashi, Shiho; Leloudas, Giorgos; Savaglio, Sandra; Schady, Patricia; Schmidl, Sebastian; Schweyer, Tassilo; Sudilovsky, Vladimir; Tanga, Mohit; Updike, Adria C; van Eerten, Hendrik; Varela, Karla

    2015-07-09

    A new class of ultra-long-duration (more than 10,000 seconds) γ-ray bursts has recently been suggested. They may originate in the explosion of stars with much larger radii than those producing normal long-duration γ-ray bursts or in the tidal disruption of a star. No clear supernova has yet been associated with an ultra-long-duration γ-ray burst. Here we report that a supernova (SN 2011kl) was associated with the ultra-long-duration γ-ray burst GRB 111209A, at a redshift z of 0.677. This supernova is more than three times more luminous than type Ic supernovae associated with long-duration γ-ray bursts, and its spectrum is distinctly different. The slope of the continuum resembles those of super-luminous supernovae, but extends further down into the rest-frame ultraviolet implying a low metal content. The light curve evolves much more rapidly than those of super-luminous supernovae. This combination of high luminosity and low metal-line opacity cannot be reconciled with typical type Ic supernovae, but can be reproduced by a model where extra energy is injected by a strongly magnetized neutron star (a magnetar), which has also been proposed as the explanation for super-luminous supernovae.

  1. Rapid mixing and short storage timescale in the magma dynamics of a steady-state volcano

    NASA Astrophysics Data System (ADS)

    Petrone, Chiara Maria; Braschi, Eleonora; Francalanci, Lorella; Casalini, Martina; Tommasini, Simone

    2018-06-01

    Steady-state volcanic activity implies equilibrium between the rate of magma replenishment and eruption of compositionally homogeneous magmas, lasting for tens to thousands of years in an open conduit system. The Present-day activity of Stromboli volcano (Aeolian Islands, Southern Italy) has long been recognised as typical of a steady-state volcano, with a shallow magmatic reservoir (highly porphyritic or hp-magma) continuously refilled by more mafic magma (with low phenocryst content or lp-magma) at a constant rate and accompanied by mixing, crystallisation and eruption. Our aim is to clarify the timescale and dynamics of the plumbing system at the establishment of the Present-day steady-state activity (<1.2 ka) to pinpoint the onset of the steady-state regime. We investigated the Post-Pizzo (PP) pyroclastic sequence (∼1.7-1.5 ka) and one of the Early Paroxysms (EP) of the Present-day activity, focusing on the clinopyroxene population. Whole rock and clinopyroxene compositional variation among the PP and EP magmas is consistent with the time progression of the Stromboli system towards more mafic and lower 87Sr/86Sr compositions, pointing to the chemical and isotopic signature of the Present-day activity. Clinopyroxenes from both PP and EP record a complex history with compositional zoning that reflects growth in three different melt domains: a high-Mg# proto-lp recharging magma, a low-Mg# proto-hp resident magma, and a transient intermediate-Mg# magma. These are the result of complex turbulent flow fields and mixing regimes produced by repeated injections of the proto-lp magma in the shallow proto-hp magma reservoir. During the PP period the magmatic system was already able to regain the pre-input proto-hp composition, gradually changing toward a less evolved signature after the injection(s) of the more mafic proto-lp magma, owing to efficient (days to a few years) stirring and melt homogenisation (i.e., homogenisation time < residence time). Based upon Fe

  2. Using the ultra-long pulse width pulsed dye laser and elliptical spot to treat resistant nasal telangiectasia.

    PubMed

    Madan, Vishal; Ferguson, Janice

    2010-01-01

    Thick linear telangiectasia on the ala nasi and nasolabial crease can be resistant to treatment with the potassium-titanyl-phosphate (KTP) laser and the traditional round spot on a pulsed dye laser (PDL). We evaluated the efficacy of a 3 mm x 10 mm elliptical spot using the ultra-long pulse width on a Candela Vbeam(R) PDL for treatment of PDL- and KTP laser-resistant nasal telangiectasia. Nasal telangiectasia resistant to PDL (12 patients) and KTP laser (12 patients) in 18 patients were treated with a 3 mm x 10 mm elliptical spot on the ultra-long pulse pulsed dye laser (ULPDL) utilising long pulse width [595 nm, 40 ms, double pulse, 30:20 dynamic cooling device (DCD)]. Six patients had previously received treatment with both PDL and KTP laser prior to ULPDL (40 treatments, range1-4, mean 2.2). Complete clearance was seen in ten patients, and eight patients displayed more than 80% improvement after ULPDL treatment. Self-limiting purpura occurred with round spot PDL and erythema with KTP laser and ULPDL. Subtle linear furrows along the treatment sites were seen in three patients treated with the KTP laser. ULPDL treatment delivered using a 3 mm x 10 mm elliptical spot was non-purpuric and highly effective in the treatment of nasal telangiectasia resistant to KTP laser and PDL.

  3. Time-Resolved X-Ray Magnetic Circular Dichroism - A Selective Probe of Magnetization Dynamics on Nanosecond Timescales

    NASA Astrophysics Data System (ADS)

    Pizzini, Stefania; Vogel, Jan; Bonfim, Marlio; Fontaine, Alain

    Many synchrotron radiation techniques have been developed in the last 15 years for studying the magnetic properties of thin-film materials. The most attractive properties of synchrotron radiation are its energy tunability and its time structure. The first property allows measurements in resonant conditions at an absorption edge of each of the magnetic elements constituting the probed sample, and the latter allows time-resolved measurements on subnanosecond timescales. In this review, we introduce some of the synchrotron-based techniques used for magnetic investigations. We then describe in detail X-ray magnetic circular dichroism (XMCD) and how time-resolved XMCD studies can be carried out in the pump-probe mode. Finally, we illustrate some applications to magnetization reversal dynamics in spin valves and tunnel junctions, using fast magnetic field pulses applied along the easy magnetization axis of the samples. Thanks to the element-selectivity of X-ray absorption spectroscopy, the magnetization dynamics of the soft (Permalloy) and the hard (cobalt) layers can be studied independently. In the case of spin valves, this allowed us to show that two magnetic layers that are strongly coupled in a static regime can become uncoupled on nanosecond timescales.Present address: Universidade Federal do Paraná, Centro Politécnico CP 19011, Curitiba - PR CEP 81531-990, Brazil

  4. Timescale analysis of rule-based biochemical reaction networks

    PubMed Central

    Klinke, David J.; Finley, Stacey D.

    2012-01-01

    The flow of information within a cell is governed by a series of protein-protein interactions that can be described as a reaction network. Mathematical models of biochemical reaction networks can be constructed by repetitively applying specific rules that define how reactants interact and what new species are formed upon reaction. To aid in understanding the underlying biochemistry, timescale analysis is one method developed to prune the size of the reaction network. In this work, we extend the methods associated with timescale analysis to reaction rules instead of the species contained within the network. To illustrate this approach, we applied timescale analysis to a simple receptor-ligand binding model and a rule-based model of Interleukin-12 (IL-12) signaling in näive CD4+ T cells. The IL-12 signaling pathway includes multiple protein-protein interactions that collectively transmit information; however, the level of mechanistic detail sufficient to capture the observed dynamics has not been justified based upon the available data. The analysis correctly predicted that reactions associated with JAK2 and TYK2 binding to their corresponding receptor exist at a pseudo-equilibrium. In contrast, reactions associated with ligand binding and receptor turnover regulate cellular response to IL-12. An empirical Bayesian approach was used to estimate the uncertainty in the timescales. This approach complements existing rank- and flux-based methods that can be used to interrogate complex reaction networks. Ultimately, timescale analysis of rule-based models is a computational tool that can be used to reveal the biochemical steps that regulate signaling dynamics. PMID:21954150

  5. Adaptive Equilibrium Regulation: A Balancing Act in Two Timescales

    PubMed Central

    Boker, Steven M.

    2015-01-01

    An equilibrium involves a balancing of forces. Just as one maintains upright posture in standing or walking, many self-regulatory and interpersonal behaviors can be framed as a balancing act between an ever changing environment and within-person processes. The emerging balance between person and environment, the equilibria, are dynamic and adaptive in response to development and learning. A distinction is made between equilibrium achieved solely due to a short timescale balancing of forces and a longer timescale preferred equilibrium which we define as a state towards which the system slowly adapts. Together, these are developed into a framework that this article calls Adaptive Equilibrium Regulation (ÆR), which separates a regulatory process into two timescales: a faster regulation that automatically balances forces and a slower timescale adaptation process that reconfigures the fast regulation so as to move the system towards its preferred equilibrium when an environmental force persists over the longer timescale. This way of thinking leads to novel models for the interplay between multiple timescales of behavior, learning, and development. PMID:27066197

  6. Great Thermal Conductivity Enhancement of Silicone Composite with Ultra-Long Copper Nanowires.

    PubMed

    Zhang, Liye; Yin, Junshan; Yu, Wei; Wang, Mingzhu; Xie, Huaqing

    2017-12-01

    In this paper, ultra-long copper nanowires (CuNWs) were successfully synthesized at a large scale by hydrothermal reduction of divalent copper ion using oleylamine and oleic acid as dual ligands. The characteristic of CuNWs is hard and linear, which is clearly different from graphene nanoplatelets (GNPs) and multi-wall carbon nanotubes (MWCNTs). The thermal properties and models of silicone composites with three nanomaterials have been mainly researched. The maximum of thermal conductivity enhancement is up to 215% with only 1.0 vol.% CuNW loading, which is much higher than GNPs and MWCNTs. It is due to the ultra-long CuNWs with a length of more than 100 μm, which facilitates the formation of effective thermal-conductive networks, resulting in great enhancement of thermal conductivity.

  7. Great Thermal Conductivity Enhancement of Silicone Composite with Ultra-Long Copper Nanowires

    NASA Astrophysics Data System (ADS)

    Zhang, Liye; Yin, Junshan; Yu, Wei; Wang, Mingzhu; Xie, Huaqing

    2017-07-01

    In this paper, ultra-long copper nanowires (CuNWs) were successfully synthesized at a large scale by hydrothermal reduction of divalent copper ion using oleylamine and oleic acid as dual ligands. The characteristic of CuNWs is hard and linear, which is clearly different from graphene nanoplatelets (GNPs) and multi-wall carbon nanotubes (MWCNTs). The thermal properties and models of silicone composites with three nanomaterials have been mainly researched. The maximum of thermal conductivity enhancement is up to 215% with only 1.0 vol.% CuNW loading, which is much higher than GNPs and MWCNTs. It is due to the ultra-long CuNWs with a length of more than 100 μm, which facilitates the formation of effective thermal-conductive networks, resulting in great enhancement of thermal conductivity.

  8. Thermal Emissions Spanning the Prompt and the Afterglow Phases of the Ultra-long GRB 130925A

    NASA Astrophysics Data System (ADS)

    Basak, Rupal; Rao, A. R.

    2015-07-01

    GRB 130925A is an ultra-long gamma-ray burst (GRB), and it shows clear evidence for thermal emission in the soft X-ray data of the Swift/X-ray Telescope (XRT; ∼0.5 keV), lasting until the X-ray afterglow phase. Due to the long duration of the GRB, the burst could be studied in hard X-rays with high-resolution focusing detectors (NuSTAR). The blackbody temperature, as measured by the Swift/XRT, shows a decreasing trend until the late phase (Piro et al.) whereas the high-energy data reveal a significant blackbody component during the late epochs at an order of magnitude higher temperature (∼5 keV) compared to contemporaneous low energy data (Bellm et al.). We resolve this apparent contradiction by demonstrating that a model with two black bodies and a power law (2BBPL) is consistent with the data right from the late prompt emission to the afterglow phase. Both blackbodies show a similar cooling behavior up to late times. We invoke a structured jet, having a fast spine and a slower sheath layer, to identify the location of these blackbodies. Independent of the physical interpretation, we propose that the 2BBPL model is a generic feature of the prompt emission of all long GRBs, and the thermal emission found in the afterglow phase of different GRBs reflects the lingering thermal component of the prompt emission with different timescales. We strengthen this proposal by pointing out a close similarity between the spectral evolutions of this GRB and GRB 090618, a source with significant wide band data during the early afterglow phase.

  9. Multi-timescale data assimilation for atmosphere–ocean state estimates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Steiger, Nathan; Hakim, Gregory

    2016-06-24

    Paleoclimate proxy data span seasonal to millennial timescales, and Earth's climate system has both high- and low-frequency components. Yet it is currently unclear how best to incorporate multiple timescales of proxy data into a single reconstruction framework and to also capture both high- and low-frequency components of reconstructed variables. Here we present a data assimilation approach that can explicitly incorporate proxy data at arbitrary timescales. The principal advantage of using such an approach is that it allows much more proxy data to inform a climate reconstruction, though there can be additional benefits. Through a series of offline data-assimilation-based pseudoproxy experiments,more » we find that atmosphere–ocean states are most skillfully reconstructed by incorporating proxies across multiple timescales compared to using proxies at short (annual) or long (~ decadal) timescales alone. Additionally, reconstructions that incorporate long-timescale pseudoproxies improve the low-frequency components of the reconstructions relative to using only high-resolution pseudoproxies. We argue that this is because time averaging high-resolution observations improves their covariance relationship with the slowly varying components of the coupled-climate system, which the data assimilation algorithm can exploit. These results are consistent across the climate models considered, despite the model variables having very different spectral characteristics. Furthermore, our results also suggest that it may be possible to reconstruct features of the oceanic meridional overturning circulation based on atmospheric surface temperature proxies, though here we find such reconstructions lack spectral power over a broad range of frequencies.« less

  10. Impact of external forcing on simulated hydroclimate from interannual to multicentennial timescales

    NASA Astrophysics Data System (ADS)

    Roldán, Pedro; Fidel González-Rouco, Jesús; Melo-Aguilar, Camilo

    2017-04-01

    During the last millennium, external forcing experienced important changes in different timescales. It has been demostrated that these changes had an impact on climate. In particular, changes in solar activity, volcanic eruptions and emissions of greenhouse gases are related to short-term and long-term changes in global temperatures, with situations of higher total external forcing generally related with higher global and hemispherical temperatures, and conversely with situations of lower forcing. This connection is clearly observed in climate simulations from different models and in proxy-based reconstructions. The changes in external forcing can also explain certain changes in atmospheric dynamics and hydroclimate, although in this case it is in general more difficult to trace causality arguments. Analyses based on simulations from two different models (ECHO-G and CESM-LME) have been performed, to assess the impact of external forcing on climate in timescales ranging from interannual to multicentennial. Various climatic variables have been analysed, including temperature, sea level pressure, surface wind, precipitation and soil moisture. For interannual timescales, composites have been defined with the years before and after the main volcanic eruptions of the last millennium as well as the minima of solar activity during this period. For longer timescales, a Principal Component analysis has been performed, to try to separate the signal of external forcing from that of internal variability. This has been done for the whole millennium and for the pre-industrial period, to assess the difference between natural and anthropogenic forcing. For multicentennial timescales, composites for the Medieval Climate Anomaly (MCA; ca. 950-1250), the Little Ice Age (LIA; ca. 1450-1850) and the 20th Century have been compared. These three periods were respectively characterised by higher, lower and higher forcing. This allows to assess the contribution of external forcing to the

  11. Sequence-specific backbone resonance assignments and microsecond timescale molecular dynamics simulation of human eosinophil-derived neurotoxin.

    PubMed

    Gagné, Donald; Narayanan, Chitra; Bafna, Khushboo; Charest, Laurie-Anne; Agarwal, Pratul K; Doucet, Nicolas

    2017-10-01

    Eight active canonical members of the pancreatic-like ribonuclease A (RNase A) superfamily have been identified in human. All structural homologs share similar RNA-degrading functions, while also cumulating other various biological activities in different tissues. The functional homologs eosinophil-derived neurotoxin (EDN, or RNase 2) and eosinophil cationic protein (ECP, or RNase 3) are known to be expressed and secreted by eosinophils in response to infection, and have thus been postulated to play an important role in host defense and inflammatory response. We recently initiated the biophysical and dynamical investigation of several vertebrate RNase homologs and observed that clustering residue dynamics appear to be linked with the phylogeny and biological specificity of several members. Here we report the 1 H, 13 C and 15 N backbone resonance assignments of human EDN (RNase 2) and its molecular dynamics simulation on the microsecond timescale, providing means to pursue this comparative atomic-scale functional and dynamical analysis by NMR and computation over multiple time frames.

  12. THE UNUSUAL RADIO AFTERGLOW OF THE ULTRA-LONG GAMMA-RAY BURST GRB 130925A

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Horesh, Assaf; Cenko, S. Bradley; Perley, Daniel A.

    2015-10-10

    GRB 130925A is one of the recent additions to the growing family of ultra-long gamma-ray bursts (GRBs; T90 ≳1000 s). While the X-ray emission of ultra-long GRBs have been studied extensively in the past, no comprehensive radio data set has been obtained so far. We report here the early discovery of an unusual radio afterglow associated with the ultra-long GRB 130925A. The radio emission peaks at low-frequencies (∼7 GHz) at early times, only 2.2 days after the burst occurred. More notably, the radio spectrum at frequencies above 10 GHz exhibits a rather steep cut-off, compared to other long GRB radiomore » afterglows. This cut-off can be explained if the emitting electrons are either mono-energetic or originate from a rather steep, dN/dE ∝ E{sup −4}, power-law energy distribution. An alternative electron acceleration mechanism may be required to produce such an electron energy distribution. Furthermore, the radio spectrum exhibits a secondary underlying and slowly varying component. This may hint that the radio emission we observed is comprised of emission from both a reverse and a forward shock. We discuss our results in comparison with previous works that studied the unusual X-ray spectrum of this event and discuss the implications of our findings on progenitor scenarios.« less

  13. Modeling Long-Term Fluvial Incision : Shall we Care for the Details of Short-Term Fluvial Dynamics?

    NASA Astrophysics Data System (ADS)

    Lague, D.; Davy, P.

    2008-12-01

    Fluvial incision laws used in numerical models of coupled climate, erosion and tectonics systems are mainly based on the family of stream power laws for which the rate of local erosion E is a power function of the topographic slope S and the local mean discharge Q : E = K Qm Sn. The exponents m and n are generally taken as (0.35, 0.7) or (0.5, 1), and K is chosen such that the predicted topographic elevation given the prevailing rates of precipitation and tectonics stay within realistic values. The resulting topographies are reasonably realistic, and the coupled system dynamics behaves somehow as expected : more precipitation induces increased erosion and localization of the deformation. Yet, if we now focus on smaller scale fluvial dynamics (the reach scale), recent advances have suggested that discharge variability, channel width dynamics or sediment flux effects may play a significant role in controlling incision rates. These are not factored in the simple stream power law model. In this work, we study how these short- term details propagate into long-term incision dynamics within the framework of surface/tectonics coupled numerical models. To upscale the short term dynamics to geological timescales, we use a numerical model of a trapezoidal river in which vertical and lateral incision processes are computed from fluid shear stress at a daily timescale, sediment transport and protection effects are factored in, as well as a variable discharge. We show that the stream power law model might still be a valid model but that as soon as realistic effects are included such as a threshold for sediment transport, variable discharge and dynamic width the resulting exponents m and n can be as high as 2 and 4. This high non-linearity has a profound consequence on the sensitivity of fluvial relief to incision rate. We also show that additional complexity does not systematically translates into more non-linear behaviour. For instance, considering only a dynamical width

  14. Discovery of a Similar to 5 Day Characteristic Timescale in the Kepler Power Spectrum of Zw 229-15

    NASA Technical Reports Server (NTRS)

    Edelson, R.; Vaughan, S.; Malkan, M.; Kelly, B. C.; Smith, K. L.; Boyd, P. T.; Mushotzky, R.

    2014-01-01

    We present time series analyses of the full Kepler dataset of Zw 229- 15. This Kepler light curve- with a baseline greater than three years, composed of virtually continuous, evenly sampled 30-minute measurements - is unprecedented in its quality and precision. We utilize two methods of power spectral analysis to investigate the optical variability and search for evidence of a bend frequency associated with a characteristic optical variability timescale. Each method yields similar results. The first interpolates across data gaps to use the standard Fourier periodogram. The second, using the CARMA-based time-domain modeling technique of Kelly et al., does not need evenly-sampled data. Both methods find excess power at high frequencies that may be due to Kepler instrumental effects. More importantly both also show strong bends (delta alpha is approx. 2) at timescales of approx. 5 days, a feature similar to those seen in the X-ray PSDs of AGN but never before in the optical. This observed approx. 5 day timescale may be associated with one of several physical processes potentially responsible for the variability. A plausible association could be made with light -crossing, dynamical or thermal timescales, depending on the assumed value of the accretion disk size and on unobserved disk parameters such as alpha and H¬R. This timescale is not consistent with the viscous timescale, which would be years in a approx. 10(exp7) solar mass AGN such as Zw 229- 15. However there must be a second bend on long (& 1 year) timescales, and that feature could be associated with the viscous timescale.

  15. Predicting Instability Timescales in Closely-Packed Planetary Systems

    NASA Astrophysics Data System (ADS)

    Tamayo, Daniel; Hadden, Samuel; Hussain, Naireen; Silburt, Ari; Gilbertson, Christian; Rein, Hanno; Menou, Kristen

    2018-04-01

    Many of the multi-planet systems discovered around other stars are maximally packed. This implies that simulations with masses or orbital parameters too far from the actual values will destabilize on short timescales; thus, long-term dynamics allows one to constrain the orbital architectures of many closely packed multi-planet systems. A central challenge in such efforts is the large computational cost of N-body simulations, which preclude a full survey of the high-dimensional parameter space of orbital architectures allowed by observations. I will present our recent successes in training machine learning models capable of reliably predicting orbital stability a million times faster than N-body simulations. By engineering dynamically relevant features that we feed to a gradient-boosted decision tree algorithm (XGBoost), we are able to achieve a precision and recall of 90% on a holdout test set of N-body simulations. This opens a wide discovery space for characterizing new exoplanet discoveries and for elucidating how orbital architectures evolve through time as the next generation of spaceborne exoplanet surveys prepare for launch this year.

  16. Response of integrate-and-fire neurons to noisy inputs filtered by synapses with arbitrary timescales: firing rate and correlations.

    PubMed

    Moreno-Bote, Rubén; Parga, Néstor

    2010-06-01

    Delivery of neurotransmitter produces on a synapse a current that flows through the membrane and gets transmitted into the soma of the neuron, where it is integrated. The decay time of the current depends on the synaptic receptor's type and ranges from a few (e.g., AMPA receptors) to a few hundred milliseconds (e.g., NMDA receptors). The role of the variety of synaptic timescales, several of them coexisting in the same neuron, is at present not understood. A prime question to answer is which is the effect of temporal filtering at different timescales of the incoming spike trains on the neuron's response. Here, based on our previous work on linear synaptic filtering, we build a general theory for the stationary firing response of integrate-and-fire (IF) neurons receiving stochastic inputs filtered by one, two, or multiple synaptic channels, each characterized by an arbitrary timescale. The formalism applies to arbitrary IF model neurons and arbitrary forms of input noise (i.e., not required to be gaussian or to have small amplitude), as well as to any form of synaptic filtering (linear or nonlinear). The theory determines with exact analytical expressions the firing rate of an IF neuron for long synaptic time constants using the adiabatic approach. The correlated spiking (cross-correlations function) of two neurons receiving common as well as independent sources of noise is also described. The theory is illustrated using leaky, quadratic, and noise-thresholded IF neurons. Although the adiabatic approach is exact when at least one of the synaptic timescales is long, it provides a good prediction of the firing rate even when the timescales of the synapses are comparable to that of the leak of the neuron; it is not required that the synaptic time constants are longer than the mean interspike intervals or that the noise has small variance. The distribution of the potential for general IF neurons is also characterized. Our results provide powerful analytical tools that

  17. On equatorially symmetric and antisymmetric geomagnetic secular variation timescales

    NASA Astrophysics Data System (ADS)

    Amit, Hagay; Coutelier, Maélie; Christensen, Ulrich R.

    2018-03-01

    It has been suggested that the secular variation (SV) timescales of the geomagnetic field vary as 1 / ℓ (where ℓ is the spherical harmonic degree), except for the dipole. Here we propose that the same scaling law applies for SV timescales defined for different symmetry classes of the geomagnetic field and SV. We decompose the field and its SV into symmetric and antisymmetric parts and show in geomagnetic field models and numerical dynamo simulations that the corresponding SV timescales also vary as 1 / ℓ , again except for the dipole. The time-average antisymmetric/symmetric SV timescales are larger/smaller than the total, respectively. The difference in SV timescales between these two symmetry classes is probably due to different degrees of alignment of the core flow with different magnetic field structures at the core-mantle boundary. The symmetric dipole SV timescale in the recent geomagnetic field and in long-term time-averages from numerical dynamos is below the extrapolated 1 / ℓ curve, whereas before ∼ 1965 the geomagnetic dipole tilt was rather steady and the symmetric dipole SV timescale exceeded the extrapolated 1 / ℓ curve. We hypothesize that the period of nearly steady geomagnetic dipole tilt between 1810-1965 was anomalous for the geodynamo. Overall, the deviation of the dipole SV timescales from the 1 / ℓ curves may indicate that magnetic diffusion contributes to the dipole SV more than it does for higher degrees.

  18. Engineering dynamical control of cell fate switching using synthetic phospho-regulons

    PubMed Central

    Gordley, Russell M.; Williams, Reid E.; Bashor, Caleb J.; Toettcher, Jared E.; Yan, Shude; Lim, Wendell A.

    2016-01-01

    Many cells can sense and respond to time-varying stimuli, selectively triggering changes in cell fate only in response to inputs of a particular duration or frequency. A common motif in dynamically controlled cells is a dual-timescale regulatory network: although long-term fate decisions are ultimately controlled by a slow-timescale switch (e.g., gene expression), input signals are first processed by a fast-timescale signaling layer, which is hypothesized to filter what dynamic information is efficiently relayed downstream. Directly testing the design principles of how dual-timescale circuits control dynamic sensing, however, has been challenging, because most synthetic biology methods have focused solely on rewiring transcriptional circuits, which operate at a single slow timescale. Here, we report the development of a modular approach for flexibly engineering phosphorylation circuits using designed phospho-regulon motifs. By then linking rapid phospho-feedback with slower downstream transcription-based bistable switches, we can construct synthetic dual-timescale circuits in yeast in which the triggering dynamics and the end-state properties of the ON state can be selectively tuned. These phospho-regulon tools thus open up the possibility to engineer cells with customized dynamical control. PMID:27821768

  19. Cavitation in confined water: ultra-fast bubble dynamics

    NASA Astrophysics Data System (ADS)

    Vincent, Olivier; Marmottant, Philippe

    2012-02-01

    In the hydraulic vessels of trees, water can be found at negative pressure. This metastable state, corresponding to mechanical tension, is achieved by evaporation through a porous medium. It can be relaxed by cavitation, i.e. the sudden nucleation of vapor bubbles. Harmful for the tree due to the subsequent emboli of sap vessels, cavitation is on the contrary used by ferns to eject spores very swiftly. We will focus here on the dynamics of the cavitation bubble, which is of primary importance to explain the previously cited natural phenomena. We use the recently developed method of artificial tress, using transparent hydrogels as the porous medium. Our experiments, on water confined in micrometric hydrogel cavities, show an extremely fast dynamics: bubbles are nucleated at the microsecond timescale. For cavities larger than 100 microns, the bubble ``rings'' with damped oscillations at MHz frequencies, whereas for smaller cavities the oscillations become overdamped. This rich dynamics can be accounted for by a model we developed, leading to a modified Rayleigh-Plesset equation. Interestingly, this model predicts the impossibility to nucleate bubbles above a critical confinement that depends on liquid negative pressure and corresponds to approximately 100 nm for 20 MPa tensions.

  20. Lagged processes and critical timescales in boreal forest response to climate

    NASA Astrophysics Data System (ADS)

    Wofsy, S. C.; Dunn, A. L.; Amiro, B. D.; Barr, A.; Rocha, A. V.; Goulden, M. L.

    2006-12-01

    Long-term eddy covariance datasets have recorded the response of boreal ecosystems to climate on timescales up to decadal (Dunn et al. 2006, Barr et al. 2006). Carbon balances in these forests are very dynamic, responding to climatic anomalies on timescales of months to years. A boreal black spruce forest in central Manitoba, Canada, was a source of carbon to the atmosphere in the mid-1990s (55 g C m^{- 2} y-1, 1995-1997), but switched to a sink in recent years (-25 g C m-2 y-1, 2003-2005). The short-term carbon exchange at this site was strongly controlled by temperature, but on long timescales the water balance was more important (Dunn et al. 2006). In a boreal aspen forest in central Saskatchewan, Canada, temperature was the main driver of phenology and canopy duration, but drought status, and especially the persistence of drought over multiple years, was a critical control on ecosystem respiration and resultant carbon balance (Barr et al. 2006). Lagged processes are especially important in the boreal forest: Dunn et al. (2006) found that carbon balances, and especially ecosystem respiration, were strongly controlled by the integrated water balance over preceding years, suggesting that the effects of climatic anomalies are expressed slowly in these forests. Rocha et al. (2006) found similar evidence in tree-ring cores from the NOBS site, which showed a strong correlation with lagged water balances, suggesting that wood growth in these forests is a process integrating over prior years. In a tree-ring analysis across aspen stands in western Canada, Hogg et al. (2005) found that current and lagged (up to four years) moisture status were critical factors regulating ecosystem carbon balance. These results from long-term boreal datasets suggest that the vulnerability of these forests to climate change will be strongly dependent on the future balance between precipitation and temperature. Persistent perturbations to the local climate will likely shift overall biome

  1. Ultra-high-frequency chaos in a time-delay electronic device with band-limited feedback.

    PubMed

    Illing, Lucas; Gauthier, Daniel J

    2006-09-01

    We report an experimental study of ultra-high-frequency chaotic dynamics generated in a delay-dynamical electronic device. It consists of a transistor-based nonlinearity, commercially-available amplifiers, and a transmission-line for feedback. The feedback is band-limited, allowing tuning of the characteristic time-scales of both the periodic and high-dimensional chaotic oscillations that can be generated with the device. As an example, periodic oscillations ranging from 48 to 913 MHz are demonstrated. We develop a model and use it to compare the experimentally observed Hopf bifurcation of the steady-state to existing theory [Illing and Gauthier, Physica D 210, 180 (2005)]. We find good quantitative agreement of the predicted and the measured bifurcation threshold, bifurcation type and oscillation frequency. Numerical integration of the model yields quasiperiodic and high dimensional chaotic solutions (Lyapunov dimension approximately 13), which match qualitatively the observed device dynamics.

  2. Storm- Time Dynamics of Ring Current Protons: Implications for the Long-Term Energy Budget in the Inner Magnetosphere.

    NASA Astrophysics Data System (ADS)

    Gkioulidou, M.; Ukhorskiy, A. Y.; Mitchell, D. G.; Lanzerotti, L. J.

    2015-12-01

    The ring current energy budget plays a key role in the global electrodynamics of Earth's space environment. Pressure gradients developed in the inner magnetosphere can shield the near-Earth region from solar wind-induced electric fields. The distortion of Earth's magnetic field due to the ring current affects the dynamics of particles contributing both to the ring current and radiation belts. Therefore, understanding the long-term evolution of the inner magnetosphere energy content is essential. We have investigated the evolution of ring current proton pressure (7 - 600 keV) in the inner magnetosphere based on data from the Radiation Belt Storm Probes Ion Composition Experiment (RBSPICE) instrument aboard Van Allen Probe B throughout the year 2013. We find that although the low-energy component of the protons (< 80 keV) is governed by convective timescales and is very well correlated with the Dst index, the high-energy component (>100 keV) varies on much longer timescales and shows either no or anti-correlation with the Dst index. Interestingly, the contributions of the high- and low-energy protons to the total energy content are comparable. Our results indicate that the proton dynamics, and as a consequence the total energy budget in the inner magnetosphere (inside geosynchronous orbit), is not strictly controlled by storm-time timescales as those are defined by the Dst index.

  3. Stimulated Brillouin scattering in ultra-long distributed feedback Bragg gratings in standard optical fiber.

    PubMed

    Loranger, Sébastien; Lambin-Iezzi, Victor; Wahbeh, Mamoun; Kashyap, Raman

    2016-04-15

    Distributed feedback (DFB) fiber Bragg gratings (FBG) are widely used as narrow-band filters and single-mode cavities for lasers. Recently, a nonlinear generation has been shown in 10-20 cm DFB gratings in a highly nonlinear fiber. First, we show in this Letter a novel fabrication technique of ultra-long DFBs in a standard fiber (SMF-28). Second, we demonstrate nonlinear generation in such gratings. A particular inscription technique was used to fabricate all-in-phase ultra-long FBG and to implement reproducible phase shift to form a DFB mode. We demonstrate stimulated Brillouin scattering (SBS) emission from this DFB mode and characterize the resulting laser. It seems that such a SBS based DFB laser stabilizes a pump's jittering and reduces its linewidth.

  4. Ultra-Low Power Dynamic Knob in Adaptive Compressed Sensing Towards Biosignal Dynamics.

    PubMed

    Wang, Aosen; Lin, Feng; Jin, Zhanpeng; Xu, Wenyao

    2016-06-01

    Compressed sensing (CS) is an emerging sampling paradigm in data acquisition. Its integrated analog-to-information structure can perform simultaneous data sensing and compression with low-complexity hardware. To date, most of the existing CS implementations have a fixed architectural setup, which lacks flexibility and adaptivity for efficient dynamic data sensing. In this paper, we propose a dynamic knob (DK) design to effectively reconfigure the CS architecture by recognizing the biosignals. Specifically, the dynamic knob design is a template-based structure that comprises a supervised learning module and a look-up table module. We model the DK performance in a closed analytic form and optimize the design via a dynamic programming formulation. We present the design on a 130 nm process, with a 0.058 mm (2) fingerprint and a 187.88 nJ/event energy-consumption. Furthermore, we benchmark the design performance using a publicly available dataset. Given the energy constraint in wireless sensing, the adaptive CS architecture can consistently improve the signal reconstruction quality by more than 70%, compared with the traditional CS. The experimental results indicate that the ultra-low power dynamic knob can provide an effective adaptivity and improve the signal quality in compressed sensing towards biosignal dynamics.

  5. The enigmatic ultra-long run-out of seafloor density driven flows

    NASA Astrophysics Data System (ADS)

    Dorrell, R. M.

    2017-12-01

    Dilute, particulate-laden, density-driven flows - turbidity currents - are a predominant mechanism for transporting sediment from source to sink in deep marine environments. These flows sculpt channels on the seafloor and, as evidenced by a wealth of bathymetric data, can travel for >1000km, forming some of the largest sedimentary landforms on the planet. For turbidity currents to travel such large dsitances, sediment must be self-maintained in suspension, i.e., be in a state of autosuspension. It has been shown that such self-maintained sediment suspensions can only occur whilst inertial forces are greater than gravitational forces, entailing supercritical flow. This conclusion is paradoxical, as inertia dominated flows rapidly entrain fluid, thereby thickening and slowing to become subcritical. However, current theory can only truly be applied to the proximal upper slope regions of seafloor channels where incised flows are fully confined. This contrasts with the distal reaches of long run out turbidity current systems, where the flow is only partially confined through self-channelization. Here it is shown that overspill of partially confined flow has a significant effect on the hydro- and morphodynamics of turbidity current systems. A new model is derived that shows that channel overspill acts to negate the effects of ambient fluid entrainment: a dynamic balance that limits increases in flow depth and maintains supercritical flow throughout the channel. In the new model mass, momentum and energy conservation is modulated by flow overspill onto channel banks, necessarily requiring description of the vertical structure of the flow. Analysis of continuously stratified steady state flow dynamics shows that the integration of overspill and stratification is necessary to enable maintained autosuspension and thus predict the ultra-long run-out of turbidity currents.

  6. Broad timescale forcing and geomorphic mediation of tidal marsh flow and temperature dynamics

    USGS Publications Warehouse

    Enwright, Christopher; Culberson, Steven; Burau, Jon R.

    2013-01-01

    Tidal marsh functions are driven by interactions between tides, landscape morphology, and emergent vegetation. Less often considered are the diurnal pattern of tide extremes and seasonal variation of solar insolation in the mix of tidal marsh driver interactions. This work demonstrates how high-frequency hydroperiod and water temperature variability emerges from disparate timescale interactions between tidal marsh morphology, tidal harmonics, and meteorology in the San Francisco Estuary. We compare the tidal and residual flow and temperature response of neighboring tidal sloughs, one possessing natural tidal marsh morphology, and one that is modified for water control. We show that the natural tidal marsh is tuned to lunar phase and produces tidal and fortnight water temperature variability through interacting tide, meteorology, and geomorphic linkages. In contrast, temperature variability is dampened in the modified slough where overbank marsh plain connection is severed by levees. Despite geomorphic differences, a key finding is that both sloughs are heat sinks in summer by latent heat flux-driven residual upstream water advection and sensible and long-wave heat transfer. The precession of a 335-year tidal harmonic assures that these dynamics will shift in the future. Water temperature regulation appears to be a key function of natural tidal sloughs that depends critically on geomorphic mediation. We investigate approaches to untangling the relative influence of sun versus tide on residual water and temperature transport as a function of system morphology. The findings of this study likely have ecological consequences and suggest physical process metrics for tidal marsh restoration performance.

  7. Time-Scale Modification of Complex Acoustic Signals in Noise

    DTIC Science & Technology

    1994-02-04

    of a response from a closing stapler . 15 6 Short-time processing of long waveforms. 16 7 Time-scale expansion (x 2) of sequence of transients using...filter bank/overlap- add. 17 8 Time-scale expansion (x2) of a closing stapler using filter bank/overlap-add. 18 9 Composite subband time-scale...INTRODUCTION Short-duration complex sounds, as from the closing of a stapler or the tapping of a drum stick, often consist of a series of brief

  8. Reaching multi-nanosecond timescales in combined QM/MM molecular dynamics simulations through parallel horsetail sampling.

    PubMed

    Martins-Costa, Marilia T C; Ruiz-López, Manuel F

    2017-04-15

    We report an enhanced sampling technique that allows to reach the multi-nanosecond timescale in quantum mechanics/molecular mechanics molecular dynamics simulations. The proposed technique, called horsetail sampling, is a specific type of multiple molecular dynamics approach exhibiting high parallel efficiency. It couples a main simulation with a large number of shorter trajectories launched on independent processors at periodic time intervals. The technique is applied to study hydrogen peroxide at the water liquid-vapor interface, a system of considerable atmospheric relevance. A total simulation time of a little more than 6 ns has been attained for a total CPU time of 5.1 years representing only about 20 days of wall-clock time. The discussion of the results highlights the strong influence of the solvation effects at the interface on the structure and the electronic properties of the solute. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  9. Do nuclei move on an attosecond timescale in strong-field photodissociation?

    NASA Astrophysics Data System (ADS)

    Esry, B. D.

    2017-04-01

    Without the ready availability of single attosecond pulses with sufficient energy to perform pump-probe experiments, the push to measure electronic dynamics on its natural timescale of attoseconds has enlisted less direct measurements. Photoionization ``time delays'', in particular, have been measured and calculated to be on the attosecond timescale and thus have attracted considerable attention. The ultimate goal of such attosecond-scale measurements is the molecular movie - i.e., making movies of the electronic motion during chemical reactions. It has been universally assumed, however, that any measured attosecond timescales in observables relate exclusively to electronic dynamics, even during a reaction which necessarily includes nuclear motion. I will explore some of the limits of this assumption and highlight a few specific cases where it fails, emphasizing in the process that phases should be favored over ``time delays''. Supported by the Chemical Sciences, Geosciences, and Biosciences Division, Office of Basic Energy Sciences, Office of Science, U.S. Department of Energy.

  10. Scrutinizing Molecular Mechanics Force Fields on the Submicrosecond Timescale with NMR Data

    PubMed Central

    Lange, Oliver F.; van der Spoel, David; de Groot, Bert L.

    2010-01-01

    Abstract Protein dynamics on the atomic level and on the microsecond timescale has recently become accessible from both computation and experiment. To validate molecular dynamics (MD) at the submicrosecond timescale against experiment we present microsecond MD simulations in 10 different force-field configurations for two globular proteins, ubiquitin and the gb3 domain of protein G, for which extensive NMR data is available. We find that the reproduction of the measured NMR data strongly depends on the chosen force field and electrostatics treatment. Generally, particle-mesh Ewald outperforms cut-off and reaction-field approaches. A comparison to measured J-couplings across hydrogen bonds suggests that there is room for improvement in the force-field description of hydrogen bonds in most modern force fields. Our results show that with current force fields, simulations beyond hundreds of nanoseconds run an increased risk of undergoing transitions to nonnative conformational states or will persist within states of high free energy for too long, thus skewing the obtained population frequencies. Only for the AMBER99sb force field have such transitions not been observed. Thus, our results have significance for the interpretation of data obtained with long MD simulations, for the selection of force fields for MD studies and for force-field development. We hope that this comprehensive benchmark based on NMR data applied to many popular MD force fields will serve as a useful resource to the MD community. Finally, we find that for gb3, the force-field AMBER99sb reaches comparable accuracy in back-calculated residual dipolar couplings and J-couplings across hydrogen bonds to ensembles obtained by refinement against NMR data. PMID:20643085

  11. Utilization of Minor Actinides as a Fuel Component for Ultra-Long Life Bhr Configurations: Designs, Advantages and Limitations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dr. Pavel V. Tsvetkov

    2009-05-20

    This project assessed the advantages and limitations of using minor actinides as a fuel component to achieve ultra-long life Very High Temperature Reactor (VHTR) configurations. Researchers considered and compared the capabilities of pebble-bed and prismatic core designs with advanced actinide fuels to achieve ultra-long operation without refueling. Since both core designs permit flexibility in component configuration, fuel utilization, and fuel management, it is possible to improve fissile properties of minor actinides by neutron spectrum shifting through configuration adjustments. The project studied advanced actinide fuels, which could reduce the long-term radio-toxicity and heat load of high-level waste sent to a geologicmore » repository and enable recovery of the energy contained in spent fuel. The ultra-long core life autonomous approach may reduce the technical need for additional repositories and is capable to improve marketability of the Generation IV VHTR by allowing worldwide deployment, including remote regions and regions with limited industrial resources. Utilization of minor actinides in nuclear reactors facilitates developments of new fuel cycles towards sustainable nuclear energy scenarios.« less

  12. Solar Variability Magnitudes and Timescales

    NASA Astrophysics Data System (ADS)

    Kopp, Greg

    2015-08-01

    The Sun’s net radiative output varies on timescales of minutes to many millennia. The former are directly observed as part of the on-going 37-year long total solar irradiance climate data record, while the latter are inferred from solar proxy and stellar evolution models. Since the Sun provides nearly all the energy driving the Earth’s climate system, changes in the sunlight reaching our planet can have - and have had - significant impacts on life and civilizations.Total solar irradiance has been measured from space since 1978 by a series of overlapping instruments. These have shown changes in the spatially- and spectrally-integrated radiant energy at the top of the Earth’s atmosphere from timescales as short as minutes to as long as a solar cycle. The Sun’s ~0.01% variations over a few minutes are caused by the superposition of convection and oscillations, and even occasionally by a large flare. Over days to weeks, changing surface activity affects solar brightness at the ~0.1% level. The 11-year solar cycle has comparable irradiance variations with peaks near solar maxima.Secular variations are harder to discern, being limited by instrument stability and the relatively short duration of the space-borne record. Proxy models of the Sun based on cosmogenic isotope records and inferred from Earth climate signatures indicate solar brightness changes over decades to millennia, although the magnitude of these variations depends on many assumptions. Stellar evolution affects yet longer timescales and is responsible for the greatest solar variabilities.In this talk I will summarize the Sun’s variability magnitudes over different temporal ranges, showing examples relevant for climate studies as well as detections of exo-solar planets transiting Sun-like stars.

  13. Ultra-sensitive all-fibre photothermal spectroscopy with large dynamic range

    PubMed Central

    Jin, Wei; Cao, Yingchun; Yang, Fan; Ho, Hoi Lut

    2015-01-01

    Photothermal interferometry is an ultra-sensitive spectroscopic means for trace chemical detection in gas- and liquid-phase materials. Previous photothermal interferometry systems used free-space optics and have limitations in efficiency of light–matter interaction, size and optical alignment, and integration into photonic circuits. Here we exploit photothermal-induced phase change in a gas-filled hollow-core photonic bandgap fibre, and demonstrate an all-fibre acetylene gas sensor with a noise equivalent concentration of 2 p.p.b. (2.3 × 10−9 cm−1 in absorption coefficient) and an unprecedented dynamic range of nearly six orders of magnitude. The realization of photothermal interferometry with low-cost near infrared semiconductor lasers and fibre-based technology allows a class of optical sensors with compact size, ultra sensitivity and selectivity, applicability to harsh environment, and capability for remote and multiplexed multi-point detection and distributed sensing. PMID:25866015

  14. Phase stability and dynamics of entangled polymer-nanoparticle composites

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mangal, Rahul; Srivastava, Samanvaya; Archer, Lynden A.

    Nanoparticle–polymer composites, or polymer–nanoparticle composites (PNCs), exhibit unusual mechanical and dynamical features when the particle size approaches the random coil dimensions of the host polymer. Here, we harness favourable enthalpic interactions between particle-tethered and free, host polymer chains to create model PNCs, in which spherical nanoparticles are uniformly dispersed in high molecular weight entangled polymers. Investigation of the mechanical properties of these model PNCs reveals that the nanoparticles have profound effects on the host polymer motions on all timescales. On short timescales, nanoparticles slow-down local dynamics of the host polymer segments and lower the glass transition temperature. On intermediate timescales,more » where polymer chain motion is typically constrained by entanglements with surrounding molecules, nanoparticles provide additional constraints, which lead to an early onset of entangled polymer dynamics. Finally, on long timescales, nanoparticles produce an apparent speeding up of relaxation of their polymer host.« less

  15. Evolution of the protolunar disk: Dynamics, cooling timescale and implantation of volatiles onto the Earth

    NASA Astrophysics Data System (ADS)

    Charnoz, Sébastien; Michaut, Chloé

    2015-11-01

    It is thought that the Moon accreted from the protolunar disk that was assembled after the last giant impact on Earth. Due to its high temperature, the protolunar disk may act as a thermochemical reactor in which the material is processed before being incorporated into the Moon. Outstanding issues like devolatilisation and istotopic evolution are tied to the disk evolution, however its lifetime, dynamics and thermodynamics are unknown. Here, we numerically explore the long term viscous evolution of the protolunar disk using a one dimensional model where the different phases (vapor and condensed) are vertically stratified. Viscous heating, radiative cooling, phase transitions and gravitational instability are accounted for whereas Moon's accretion is not considered for the moment. The viscosity of the gas, liquid and solid phases dictates the disk evolution. We find that (1) the vapor condenses into liquid in ∼10 years, (2) a large fraction of the disk mass flows inward forming a hot and compact liquid disk between 1 and 1.7 Earth's radii, a region where the liquid is gravitationally stable and can accumulate, (3) the disk finally solidifies in 103 to 105 years. Viscous heating is never balanced by radiative cooling. If the vapor phase is abnormally viscous, due to magneto-rotational instability for instance, most of the disk volatile components are transported to Earth leaving a disk enriched in refractory elements. This opens a way to form a volatile-depleted Moon and would suggest that the missing Moon's volatiles are buried today into the Earth. The disk cooling timescale may be long enough to allow for planet/disk isotopic equilibration. However large uncertainties on the disk physics remain because of the complexity of its multi-phased structure.

  16. Young Stellar Object VARiability (YSOVAR): Long Timescale Variations in the Mid-infrared

    NASA Astrophysics Data System (ADS)

    Rebull, L. M.; Cody, A. M.; Covey, K. R.; Günther, H. M.; Hillenbrand, L. A.; Plavchan, P.; Poppenhaeger, K.; Stauffer, J. R.; Wolk, S. J.; Gutermuth, R.; Morales-Calderón, M.; Song, I.; Barrado, D.; Bayo, A.; James, D.; Hora, J. L.; Vrba, F. J.; Alves de Oliveira, C.; Bouvier, J.; Carey, S. J.; Carpenter, J. M.; Favata, F.; Flaherty, K.; Forbrich, J.; Hernandez, J.; McCaughrean, M. J.; Megeath, S. T.; Micela, G.; Smith, H. A.; Terebey, S.; Turner, N.; Allen, L.; Ardila, D.; Bouy, H.; Guieu, S.

    2014-11-01

    The YSOVAR (Young Stellar Object VARiability) Spitzer Space Telescope observing program obtained the first extensive mid-infrared (3.6 and 4.5 μm) time series photometry of the Orion Nebula Cluster plus smaller footprints in 11 other star-forming cores (AFGL 490, NGC 1333, Mon R2, GGD 12-15, NGC 2264, L1688, Serpens Main, Serpens South, IRAS 20050+2720, IC 1396A, and Ceph C). There are ~29,000 unique objects with light curves in either or both IRAC channels in the YSOVAR data set. We present the data collection and reduction for the Spitzer and ancillary data, and define the "standard sample" on which we calculate statistics, consisting of fast cadence data, with epochs roughly twice per day for ~40 days. We also define a "standard sample of members" consisting of all the IR-selected members and X-ray-selected members. We characterize the standard sample in terms of other properties, such as spectral energy distribution shape. We use three mechanisms to identify variables in the fast cadence data—the Stetson index, a χ2 fit to a flat light curve, and significant periodicity. We also identified variables on the longest timescales possible of six to seven years by comparing measurements taken early in the Spitzer mission with the mean from our YSOVAR campaign. The fraction of members in each cluster that are variable on these longest timescales is a function of the ratio of Class I/total members in each cluster, such that clusters with a higher fraction of Class I objects also have a higher fraction of long-term variables. For objects with a YSOVAR-determined period and a [3.6]-[8] color, we find that a star with a longer period is more likely than those with shorter periods to have an IR excess. We do not find any evidence for variability that causes [3.6]-[4.5] excesses to appear or vanish within our data set; out of members and field objects combined, at most 0.02% may have transient IR excesses.

  17. Gaia Assorted Mass Binaries Long Excluded from SLoWPoKES (GAMBLES): Identifying Ultra-wide Binary Pairs with Components of Diverse Mass

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Oelkers, Ryan J.; Stassun, Keivan G.; Dhital, Saurav, E-mail: ryan.j.oelkers@vanderbilt.edu

    The formation and evolution of binary star systems are some of the remaining key questions in modern astronomy. Wide binary pairs (separations >10{sup 3} au) are particularly intriguing because their low binding energies make it difficult for the stars to stay gravitationally bound over extended timescales, and thus to probe the dynamics of binary formation and dissolution. Our previous SLoWPoKES catalogs, I and II, provided the largest and most complete sample of wide-binary pairs of low masses. Here we present an extension of these catalogs to a broad range of stellar masses: the Gaia Assorted Mass Binaries Long Excluded frommore » SloWPoKES (GAMBLES), comprising 8660 statistically significant wide pairs that we make available in a living online database. Within this catalog we identify a subset of 543 long-lived (dissipation timescale >1.5 Gyr) candidate binary pairs, of assorted mass, with typical separations between 10{sup 3} and 10{sup 5.5} au (0.002–1.5 pc), using the published distances and proper motions from the Tycho -Gaia Astrometric Solution and Sloan Digital Sky Survey photometry. Each pair has at most a false positive probability of 0.05; the total expectation is 2.44 false binaries in our sample. Among these, we find 22 systems with 3 components, 1 system with 4 components, and 15 pairs consisting of at least 1 possible red giant. We find the largest long-lived binary separation to be nearly 3.2 pc; even so, >76% of GAMBLES long-lived binaries have large binding energies and dissipation lifetimes longer than 1.5 Gyr. Finally, we find that the distribution of binary separations is clearly bimodal, corroborating the findings from SloWPoKES and suggesting multiple pathways for the formation and dissipation of the widest binaries in the Galaxy.« less

  18. Gaia Assorted Mass Binaries Long Excluded from SLoWPoKES (GAMBLES): Identifying Ultra-wide Binary Pairs with Components of Diverse Mass

    NASA Astrophysics Data System (ADS)

    Oelkers, Ryan J.; Stassun, Keivan G.; Dhital, Saurav

    2017-06-01

    The formation and evolution of binary star systems are some of the remaining key questions in modern astronomy. Wide binary pairs (separations >103 au) are particularly intriguing because their low binding energies make it difficult for the stars to stay gravitationally bound over extended timescales, and thus to probe the dynamics of binary formation and dissolution. Our previous SLoWPoKES catalogs, I and II, provided the largest and most complete sample of wide-binary pairs of low masses. Here we present an extension of these catalogs to a broad range of stellar masses: the Gaia Assorted Mass Binaries Long Excluded from SloWPoKES (GAMBLES), comprising 8660 statistically significant wide pairs that we make available in a living online database. Within this catalog we identify a subset of 543 long-lived (dissipation timescale >1.5 Gyr) candidate binary pairs, of assorted mass, with typical separations between 103 and 105.5 au (0.002-1.5 pc), using the published distances and proper motions from the Tycho-Gaia Astrometric Solution and Sloan Digital Sky Survey photometry. Each pair has at most a false positive probability of 0.05; the total expectation is 2.44 false binaries in our sample. Among these, we find 22 systems with 3 components, 1 system with 4 components, and 15 pairs consisting of at least 1 possible red giant. We find the largest long-lived binary separation to be nearly 3.2 pc even so, >76% of GAMBLES long-lived binaries have large binding energies and dissipation lifetimes longer than 1.5 Gyr. Finally, we find that the distribution of binary separations is clearly bimodal, corroborating the findings from SloWPoKES and suggesting multiple pathways for the formation and dissipation of the widest binaries in the Galaxy.

  19. Timescales Of The Influence Of IMF Clock Angle In Controlling The Characteristics Of Magnetospheric Dynamics

    NASA Astrophysics Data System (ADS)

    Grocott, A.; Milan, S. E.

    2013-12-01

    We exploit a database of high-latitude ionospheric electric potential patterns, derived from radar observations of plasma convection in the northern hemisphere from the years 2000 - 2006, to investigate the timescales of interplanetary magnetic field (IMF) penetration into the magnetosphere. We parameterise the convection observations by IMF clock angle, θ (the angle between geocentric solar magnetic (GSM) north and the projection of the IMF vector onto the GSM Y-Z plane), and by an IMF timescale, τB (the length of time that a similar clock angle has been maintained prior to the convection observations being made). We find that the nature of the ionospheric convection changes with IMF clock angle, as expected from previous time-averaged studies, and that for τB ~ 30 mins the convection patterns closely resemble their time-averaged counterparts. However, we also find that for certain IMF clock angles, in particular those with a northward BZ component and significant BY (dusk-dawn) component, the patterns evolve with increasing τB to less resemble their time-averaged counterparts, showing a marked enhancement in dusk-dawn asymmetry as τB approaches 10 hours. We discuss these findings in terms of the effects of the persistent penetration of a quasi-steady IMF into the magnetosphere, and its implications for understanding different modes of magnetospheric dynamics.

  20. Long-term monitoring of UK river basins: the disconnections between the timescales of hydrological processes and watershed management planning

    NASA Astrophysics Data System (ADS)

    Howden, N. J. K.; Burt, T.; Worrall, F.

    2016-12-01

    The UK has a wealth of hydrological monitoring data that has both good coverage in space since the early 1970s, and also a few locations where records have been kept continuously for almost 150 years. Such datasets offer unique opportunities for the hydrologist to consider how the concepts of stationarity, change, and definitions of "baseline" resources should be used to shape how we build models of these systems, and how we devise appropriate and sustainable watershed management strategies. In this paper we consider some of the UK's longest hydrological and biogeochemical records, to explore how long records can be used to shape such understanding and, in some cases, how they can be used to identify new modes of behaviour that need to be incorporated into management planning, from the scale of individual watersheds right up to the national scale. We also consider how key timescales of hydrological responses that are evident within the data may pose major problems for watershed management unless appropriate attention is paid to the potential impacts of processes that work over decadal timescales - much longer than sub-decadal water industry investment cycles or short-term projects for watershed management planning. We use our long-term records to show how key processes can be identified, and to illustrate how careful interpretation of shorter term records will improve decision-making for water resource management.

  1. Reorientation Timescales and Pattern Dynamics for Titan's Dunes: Does the Tail Wag the Dog or the Dragon?

    NASA Astrophysics Data System (ADS)

    Ewing, R. C.; Hayes, A. G.; McCormick, C.; Ballard, C.; Troy, S. A.

    2012-04-01

    Fields of bedform patterns persist across many orders of magnitude, from cm-scale sub-aqueous current ripples to km-scale aeolian dunes, and form with surprisingly little difference in expression despite a range of formative environments. Because of the remarkable similarity among bedform patterns, extracting information about climate and environment from these patterns is a challenge. For example, crestline orientation is not diagnostic of a particular flow regime; similar patterns form under many different flow configurations. On Titan, these challenges have played out with many attempts to reconcile dune crestline orientation with modeled and expected wind regimes. We propose that thinking about the time-scale of the change in dune orientation, rather than the orientation itself, can provide new insights on the long-term stability of the dune-field patterns and the formative wind regime. In this work, we apply the crestline re-orientation model developed by Werner and Kocurek [Geology, 1997] to the equatorial dune fields of Titan. We use Cassini Synthetic Aperture Radar images processed through a de-noising algorithm recently developed by Lucas et al. [LPSC, 2012] to measure variations in pattern parameters (crest spacing, crest length and defect density, which is the number of defect pairs per total crest length) both within and between Titan's dune fields to describe pattern maturity and identify areas where changes in dune orientation are likely to occur (or may already be occurring). Measured defect densities are similar to Earth's largest linear dune fields, such as the Namib Sand Sea and the Simpson Desert. We use measured defect densities in the Werner and Kocurek model to estimate crestline reorientation rates. We find reorientation timescales varying from ten to a hundred thousand times the average migration timescale (time to migrate a bedform one meter, ~1 Titan year according to Tokano (Aeolian Research, 2010)). Well-organized patterns have the

  2. THE BLACK HOLE CENTRAL ENGINE FOR ULTRA-LONG GAMMA-RAY BURST 111209A AND ITS ASSOCIATED SUPERNOVA 2011KL

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gao, He; You, Zhi-Qiang; Lei, Wei-Hua

    Recently, the first association between an ultra-long gamma-ray burst (GRB) and a supernova was reported, i.e., GRB 111209A/SN 2011kl, enabling us to investigate the physics of central engines or even progenitors for ultra-long GRBs. In this paper, we inspect the broadband data of GRB 111209A/SN 2011kl. The late-time X-ray light curve exhibits a GRB 121027A-like fallback bump, suggesting a black hole (BH) central engine. We thus propose a collapsar model with fallback accretion for GRB 111209A/SN 2011kl. The required model parameters, such as the total mass and radius of the progenitor star, suggest that the progenitor of GRB 111209A ismore » more likely a Wolf–Rayet star instead of a blue supergiant, and the central engine of this ultra-long burst is a BH. The implications of our results are discussed.« less

  3. Ultra-widely tunable long-period holey-fiber grating by the use of mechanical pressure.

    PubMed

    Ceballos-Herrera, D E; Torres-Gómez, I; Martínez-Ríos, A; Anzueto-Sánchez, G; Alvarez-Chávez, J A; Selvas-Aguilar, R; Sánchez-Mondragón, J J

    2007-01-20

    We report an ultra-widely tunable long-period holey-fiber grating, which combines the wide-range single-mode behavior and transverse strain sensitivity of the holey fibers with the advantages of mechanically induced long-period fiber gratings. We obtain a versatile widely tunable long-period holey-fiber grating with attractive transmission spectral characteristics for optical communications, fiber-based amplifiers, and lasers. The mechanically induced long-period holey-fiber grating shows a continuous tuning range over 500 nm, more than 12 dB depth notches with less than 0.75 dB out-of-band losses, and bandwidth control from 10 to 40 nm.

  4. FOREWORD: Modern Applications of Timescales Modern Applications of Timescales

    NASA Astrophysics Data System (ADS)

    Arias, E. F.; Lewandowski, W.

    2011-08-01

    The development of the first atomic frequency standard by Louis Essen in the 1950s is at the origin of the adoption of the atomic definition of the SI second by the 13th General Conference on Weights and Measures in 1967 and the consequent adoption of the atomic timescale. After the short reign of ephemeris time as the world's reference timescale from 1954 until 1967, Coordinated Universal Time (UTC), synchronized to universal time UT1, appeared as the best compromise for satisfying the requests of all users. At the moment of the discussion on the adoption of an atomic timescale to replace ephemeris time, the possibility of having both an astronomical time and an atomic time to serve different purposes was discussed. In the words of Essen [1], this 'would cause endless confusion as well as involving duplication of equipment'. Forty years after the adoption of the definition of Coordinated Universal Time at the International Telecommunication Union (ITU), we are close to the moment of making a decision on whether or not to decouple UTC from its tight link to the rotation of the Earth embodied in UT1. It has been a ten-year process of discussion, mainly at the ITU with the input of the International Astronomical Union, the BIPM, the Consultative Committee for Time and Frequency and other organizations. The majority opinion supported the change based on developers and users of systems that need time synchronization to a stable and continuous reference timescale; others insist on the necessity of keeping the leap-second strategy for serving some applications or just for tradition. It is our hope that, as happened in the seventies, the most appropriate definition to serve all modern applications will be adopted with the consensus of the different sectors. The redirection of international timekeeping from astronomy to metrology can be considered the benchmark that started the era of modern timescales, all based on atomic properties. The aim of this special issue of

  5. Stereocontrol of attosecond time-scale electron dynamics in ABCU using ultrafast laser pulses: a computational study.

    PubMed

    Mignolet, B; Gijsbertsen, A; Vrakking, M J J; Levine, R D; Remacle, F

    2011-05-14

    The attosecond time-scale electronic dynamics induced by an ultrashort laser pulse is computed using a multi configuration time dependent approach in ABCU (C(10)H(19)N), a medium size polyatomic molecule with a rigid cage geometry. The coupling between the electronic states induced by the strong pulse is included in the many electron Hamiltonian used to compute the electron dynamics. We show that it is possible to implement control of the electron density stereodynamics in this medium size molecule by varying the characteristics of the laser pulse, for example by polarizing the electric field either along the N-C axis of the cage, or in the plane perpendicular to it. The excitation produces an oscillatory, non-stationary, electronic state that exhibits localization of the electron density in different parts of the molecule both during and after the pulse. The coherent oscillations of the non-stationary electronic state are also demonstrated through the alternation of the dipole moment of the molecule.

  6. Interactions between rate processes with different timescales explain counterintuitive foraging patterns of arctic wintering eiders

    PubMed Central

    Heath, Joel P.; Gilchrist, H. Grant; Ydenberg, Ronald C.

    2010-01-01

    To maximize fitness, animals must respond to a variety of processes that operate at different rates or timescales. Appropriate decisions could therefore involve complex interactions among these processes. For example, eiders wintering in the arctic sea ice must consider locomotion and physiology of diving for benthic invertebrates, digestive processing rate and a nonlinear decrease in profitability of diving as currents increase over the tidal cycle. Using a multi-scale dynamic modelling approach and continuous field observations of individuals, we demonstrate that the strategy that maximizes long-term energy gain involves resting during the most profitable foraging period (slack currents). These counterintuitive foraging patterns are an adaptive trade-off between multiple overlapping rate processes and cannot be explained by classical rate-maximizing optimization theory, which only considers a single timescale and predicts a constant rate of foraging. By reducing foraging and instead digesting during slack currents, eiders structure their activity in order to maximize long-term energetic gain over an entire tide cycle. This study reveals how counterintuitive patterns and a complex functional response can result from a simple trade-off among several overlapping rate processes, emphasizing the necessity of a multi-scale approach for understanding adaptive routines in the wild and evaluating mechanisms in ecological time series. PMID:20504814

  7. Reconstructing disturbances and their biogeochemical consequences over multiple timescales

    USGS Publications Warehouse

    McLauchlan, Kendra K.; Higuera, Philip E.; Gavin, Daniel G.; Perakis, Steven S.; Mack, Michelle C.; Alexander, Heather; Battles, John; Biondi, Franco; Buma, Brian; Colombaroli, Daniele; Enders, Sara K.; Engstrom, Daniel R.; Hu, Feng Sheng; Marlon, Jennifer R.; Marshall, John; McGlone, Matt; Morris, Jesse L.; Nave, Lucas E.; Shuman, Bryan; Smithwick, Erica A.H.; Urrego, Dunia H.; Wardle, David A.; Williams, Christopher J.; Williams, Joseph J.

    2014-01-01

    Ongoing changes in disturbance regimes are predicted to cause acute changes in ecosystem structure and function in the coming decades, but many aspects of these predictions are uncertain. A key challenge is to improve the predictability of postdisturbance biogeochemical trajectories at the ecosystem level. Ecosystem ecologists and paleoecologists have generated complementary data sets about disturbance (type, severity, frequency) and ecosystem response (net primary productivity, nutrient cycling) spanning decadal to millennial timescales. Here, we take the first steps toward a full integration of these data sets by reviewing how disturbances are reconstructed using dendrochronological and sedimentary archives and by summarizing the conceptual frameworks for carbon, nitrogen, and hydrologic responses to disturbances. Key research priorities include further development of paleoecological techniques that reconstruct both disturbances and terrestrial ecosystem dynamics. In addition, mechanistic detail from disturbance experiments, long-term observations, and chronosequences can help increase the understanding of ecosystem resilience.

  8. Analyzing climate variations at multiple timescales can guide Zika virus response measures.

    PubMed

    Muñoz, Ángel G; Thomson, Madeleine C; Goddard, Lisa; Aldighieri, Sylvain

    2016-10-06

    The emergence of Zika virus (ZIKV) in Latin America and the Caribbean in 2014-2016 occurred during a period of severe drought and unusually high temperatures, conditions that have been associated with the 2015-2016 El Niño event, and/or climate change; however, no quantitative assessment has been made to date. Analysis of related flaviviruses transmitted by the same vectors suggests that ZIKV dynamics are sensitive to climate seasonality and longer-term variability and trends. A better understanding of the climate conditions conducive to the 2014-2016 epidemic may permit the development of climate-informed short and long-term strategies for ZIKV prevention and control. Using a novel timescale-decomposition methodology, we demonstrate that the extreme climate anomalies observed in most parts of South America during the current epidemic are not caused exclusively by El Niño or climate change, but by a combination of climate signals acting at multiple timescales. In Brazil, the dry conditions present in 2013-2015 are primarily explained by year-to-year variability superimposed on decadal variability, but with little contribution of long-term trends. In contrast, the warm temperatures of 2014-2015 resulted from the compound effect of climate change, decadal and year-to-year climate variability. ZIKV response strategies made in Brazil during the drought concurrent with the 2015-2016 El Niño event, may require revision in light of the likely return of rainfall associated with the borderline La Niña event expected in 2016-2017. Temperatures are likely to remain warm given the importance of long term and decadal scale climate signals. The Author(s)

  9. Building a Bridge to Deep Time: Sedimentary Systems Across Timescales

    NASA Astrophysics Data System (ADS)

    Romans, B.; Castelltort, S.; Covault, J. A.; Walsh, J. P.

    2013-12-01

    It is increasingly important to understand the complex and interdependent processes associated with sediment production, transport, and deposition at timescales relevant to civilization (annual to millennial). However, predicting the response of sedimentary systems to global environmental change across a range of timescales remains a significant challenge. For example, a significant increase in global average temperature at the Paleocene-Eocene boundary (55.8 Ma) is interpreted to have occurred over millennial timescales; however, the specific response of sedimentary systems (e.g., timing and magnitude of sediment flux variability in river systems) to that forcing is debated. Thus, using such environmental perturbations recorded in sedimentary archives as analogs for ongoing/future global change requires improved approaches to bridging across time. Additionally, the ability to bridge timescales is critical for addressing other questions about sedimentary system behavior, including signal propagation and signal versus ';noise' in the record. The geologic record provides information that can be used to develop a comprehensive understanding of process-response behavior at multiple timescales. The geomorphic ';snapshot' of present-day erosional and depositional landscapes can be examined to reconstruct the history of processes that created the observable configurations. Direct measurement and monitoring of active processes are used to constrain conceptual and numerical models and develop sedimentary system theory. But real-time observations of active Earth-surface processes are limited to the very recent, and how such processes integrate over longer timescales to transform into strata remains unknown. At longer timescales (>106 yr), the stratigraphic record is the only vestige of ancient sedimentary systems. Stratigraphic successions contain a complex record of sediment deposition and preservation, as well as the detrital material that originated in long since denuded

  10. Development of Ultra Long Duration Local Anesthetic Agents in a Rat Model

    DTIC Science & Technology

    1994-02-24

    this formulation is not toxic to the spinal cord. Initial trials with lecithin-coated bupivacaine microcrystals indic,-.. that this preparation also has...an ultra long duration local anesthetic effect, producing a 43 hour block in the rat tail. Clinical trials of this preparation in a human model are...l f _ _ _ Memorandum for LTC Dean E. Calcagni, M.D. Director, Combat Casualty Research Program USAMRDC Subject: Annual Report for Clinical

  11. Multi-timescale sediment responses across a human impacted river-estuary system

    NASA Astrophysics Data System (ADS)

    Chen, Yining; Chen, Nengwang; Li, Yan; Hong, Huasheng

    2018-05-01

    Hydrological processes regulating sediment transport from land to sea have been widely studied. However, anthropogenic factors controlling the river flow-sediment regime and subsequent response of the estuary are still poorly understood. Here we conducted a multi-timescale analysis on flow and sediment discharges during the period 1967-2014 for the two tributaries of the Jiulong River in Southeast China. The long-term flow-sediment relationship remained linear in the North River throughout the period, while the linearity showed a remarkable change after 1995 in the West River, largely due to construction of dams and reservoirs in the upland watershed. Over short timescales, rainstorm events caused the changes of suspended sediment concentration (SSC) in the rivers. Regression analysis using synchronous SSC data in a wet season (2009) revealed a delayed response (average 5 days) of the estuary to river input, and a box-model analysis established a quantitative relationship to further describe the response of the estuary to the river sediment input over multiple timescales. The short-term response is determined by both the vertical SSC-salinity changes and the sediment trapping rate in the estuary. However, over the long term, the reduction of riverine sediment yield increased marine sediments trapped into the estuary. The results of this study indicate that human activities (e.g., dams) have substantially altered sediment delivery patterns and river-estuary interactions at multiple timescales.

  12. The Importance of Rotational Time-scales in Accretion Variability

    NASA Astrophysics Data System (ADS)

    Costigan, Gráinne; Vink, Joirck; Scholz, Aleks; Testi, Leonardo; Ray, Tom

    2013-07-01

    For the first few million years, one of the dominant sources of emission from a low mass young stellar object is from accretion. This process regulates the flow of material and angular moments from the surroundings to the central object, and is thought to play an important role in the definition of the long term stellar properties. Variability is a well documented attribute of accretion, and has been observed on time-scales of from days to years. However, where these variations come from is not clear. Th current model for accretion is magnetospheric accretion, where the stellar magnetic field truncates the disc, allowing the matter to flow from the disc onto the surface of the star. This model allows for variations in the accretion rate to come from many different sources, such as the magnetic field, the circumstellar disc and the interaction of the different parts of the system. We have been studying unbiased samples of accretors in order to identify the dominant time-scales and typical magnitudes of variations. In this way different sources of variations can be excluded and any missing physics in these systems identified. Through our previous work with the Long-term Accretion Monitoring Program (LAMP), we found 10 accretors in the ChaI region, whose variability is dominated by short term variations of 2 weeks. This was the shortest time period between spectroscopic observations which spanned 15 months, and rules out large scale processes in the disk as origins of this variability. On the basis of this study we have gone further to study the accretion signature H-alpha, over the time-scales of minutes and days in a set of Herbig Ae and T Tauri stars. Using the same methods as we used in LAMP we found the dominant time-scales of variations to be days. These samples both point towards rotation period of these objects as being an important time-scale for accretion variations. This allows us to indicate which are the most likely sources of these variations.

  13. The impact of ultra-low amounts of amino-modified MMT on dynamics and properties of densely cross-linked cyanate ester resins

    NASA Astrophysics Data System (ADS)

    Bershtein, Vladimir; Fainleib, Alexander; Egorova, Larisa; Gusakova, Kristina; Grigoryeva, Olga; Kirilenko, Demid; Konnikov, Semen; Ryzhov, Valery; Yakushev, Pavel; Lavrenyuk, Natalia

    2015-04-01

    Thermostable nanocomposites based on densely cross-linked cyanate ester resins (CER), derived from bisphenol E and doped by 0.01 to 5 wt. % amino-functionalized 2D montmorillonite (MMT) nanoparticles, were synthesized and characterized using Fourier transform infrared (FTIR), transmission electron microscopy (TEM), energy dispersive X-ray spectroscopy (EDXS), wide-angle X-ray diffraction (WAXD), dynamic mechanical analysis (DMA), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), far-infrared (Far-IR), and creep rate spectroscopy (CRS) techniques. It was revealed that ultra-low additives, e.g., 0.025 to 0.1 wt. %, of amino-MMT nanolayers covalently embedded into CER network exerted an anomalously large impact on its dynamics and properties resulting, in particular, in some suppression of dynamics, increasing the onset of glass transition temperature by 30° to 40° and twofold rise of modulus in temperature range from 20°C to 200°C. Contrarily, the effects became negligibly small or even negative at increased amino-MMT contents, especially at 2 and 5 wt. %. That could be explained by TEM/EDXS data displaying predominance of individual amino-MMT nanolayers and their thin (2 to 3 nanolayers) stacks over more thick tactoids (5 to 10 nanolayers) and the large amino-MMT aggregates (100 to 500 nm in thickness) reversing the composite structure produced with increasing of amino-MMT content within CER matrix. The revealed effect of ultra-low amino-MMT content testifies in favor of the idea about the extraordinarily enhanced long-range action of the `constrained dynamics' effect in the case of densely cross-linked polymer networks.

  14. Global dynamics of selective attention and its lapses in primary auditory cortex.

    PubMed

    Lakatos, Peter; Barczak, Annamaria; Neymotin, Samuel A; McGinnis, Tammy; Ross, Deborah; Javitt, Daniel C; O'Connell, Monica Noelle

    2016-12-01

    Previous research demonstrated that while selectively attending to relevant aspects of the external world, the brain extracts pertinent information by aligning its neuronal oscillations to key time points of stimuli or their sampling by sensory organs. This alignment mechanism is termed oscillatory entrainment. We investigated the global, long-timescale dynamics of this mechanism in the primary auditory cortex of nonhuman primates, and hypothesized that lapses of entrainment would correspond to lapses of attention. By examining electrophysiological and behavioral measures, we observed that besides the lack of entrainment by external stimuli, attentional lapses were also characterized by high-amplitude alpha oscillations, with alpha frequency structuring of neuronal ensemble and single-unit operations. Entrainment and alpha-oscillation-dominated periods were strongly anticorrelated and fluctuated rhythmically at an ultra-slow rate. Our results indicate that these two distinct brain states represent externally versus internally oriented computational resources engaged by large-scale task-positive and task-negative functional networks.

  15. Long-range transport of black carbon to the Pacific Ocean and its dependence on aging timescale

    NASA Astrophysics Data System (ADS)

    Zhang, J.; Liu, J.; Tao, S.; Ban-Weiss, G. A.

    2015-06-01

    Improving the ability of global models to predict concentrations of black carbon (BC) over the Pacific Ocean is essential to evaluate the impact of BC on marine climate. In this study, we tag BC tracers from 13 source regions around the globe in a global chemical transport model MOZART-4. Numerous sensitivity simulations are carried out varying the aging timescale of BC emitted from each source region. The aging timescale for each source region is optimized by minimizing errors in vertical profiles of BC mass mixing ratios between simulations and HIAPER Pole-to-Pole Observations (HIPPO). For most HIPPO deployments, in the Northern Hemisphere, optimized aging timescales are less than half a day for BC emitted from tropical and mid-latitude source regions, and about 1 week for BC emitted from high latitude regions in all seasons except summer. We find that East Asian emissions contribute most to the BC loading over the North Pacific, while South American, African and Australian emissions dominate BC loadings over the South Pacific. Dominant source regions contributing to BC loadings in other parts of the globe are also assessed. The lifetime of BC originating from East Asia (i.e., the world's largest BC emitter) is found to be only 2.2 days, much shorter than the global average lifetime of 4.9 days, making East Asia's contribution to global burden only 36 % of BC from the second largest emitter, Africa. Thus, evaluating only relative emission rates without accounting for differences in aging timescales and deposition rates is not predictive of the contribution of a given source region to climate impacts. Our simulations indicate that lifetime of BC increases nearly linearly with aging timescale for all source regions. When aging rate is fast, the lifetime of BC is largely determined by factors that control local deposition rates (e.g. precipitation). The sensitivity of lifetime to aging timescale depends strongly on the initial hygroscopicity of freshly emitted BC

  16. Computational Models of Protein Kinematics and Dynamics: Beyond Simulation

    PubMed Central

    Gipson, Bryant; Hsu, David; Kavraki, Lydia E.; Latombe, Jean-Claude

    2016-01-01

    Physics-based simulation represents a powerful method for investigating the time-varying behavior of dynamic protein systems at high spatial and temporal resolution. Such simulations, however, can be prohibitively difficult or lengthy for large proteins or when probing the lower-resolution, long-timescale behaviors of proteins generally. Importantly, not all questions about a protein system require full space and time resolution to produce an informative answer. For instance, by avoiding the simulation of uncorrelated, high-frequency atomic movements, a larger, domain-level picture of protein dynamics can be revealed. The purpose of this review is to highlight the growing body of complementary work that goes beyond simulation. In particular, this review focuses on methods that address kinematics and dynamics, as well as those that address larger organizational questions and can quickly yield useful information about the long-timescale behavior of a protein. PMID:22524225

  17. Anti-correlated cortical networks arise from spontaneous neuronal dynamics at slow timescales.

    PubMed

    Kodama, Nathan X; Feng, Tianyi; Ullett, James J; Chiel, Hillel J; Sivakumar, Siddharth S; Galán, Roberto F

    2018-01-12

    In the highly interconnected architectures of the cerebral cortex, recurrent intracortical loops disproportionately outnumber thalamo-cortical inputs. These networks are also capable of generating neuronal activity without feedforward sensory drive. It is unknown, however, what spatiotemporal patterns may be solely attributed to intrinsic connections of the local cortical network. Using high-density microelectrode arrays, here we show that in the isolated, primary somatosensory cortex of mice, neuronal firing fluctuates on timescales from milliseconds to tens of seconds. Slower firing fluctuations reveal two spatially distinct neuronal ensembles, which correspond to superficial and deeper layers. These ensembles are anti-correlated: when one fires more, the other fires less and vice versa. This interplay is clearest at timescales of several seconds and is therefore consistent with shifts between active sensing and anticipatory behavioral states in mice.

  18. Mapping Conformational Dynamics of Proteins Using Torsional Dynamics Simulations

    PubMed Central

    Gangupomu, Vamshi K.; Wagner, Jeffrey R.; Park, In-Hee; Jain, Abhinandan; Vaidehi, Nagarajan

    2013-01-01

    All-atom molecular dynamics simulations are widely used to study the flexibility of protein conformations. However, enhanced sampling techniques are required for simulating protein dynamics that occur on the millisecond timescale. In this work, we show that torsional molecular dynamics simulations enhance protein conformational sampling by performing conformational search in the low-frequency torsional degrees of freedom. In this article, we use our recently developed torsional-dynamics method called Generalized Newton-Euler Inverse Mass Operator (GNEIMO) to study the conformational dynamics of four proteins. We investigate the use of the GNEIMO method in simulations of the conformationally flexible proteins fasciculin and calmodulin, as well as the less flexible crambin and bovine pancreatic trypsin inhibitor. For the latter two proteins, the GNEIMO simulations with an implicit-solvent model reproduced the average protein structural fluctuations and sample conformations similar to those from Cartesian simulations with explicit solvent. The application of GNEIMO with replica exchange to the study of fasciculin conformational dynamics produced sampling of two of this protein’s experimentally established conformational substates. Conformational transition of calmodulin from the Ca2+-bound to the Ca2+-free conformation occurred readily with GNEIMO simulations. Moreover, the GNEIMO method generated an ensemble of conformations that satisfy about half of both short- and long-range interresidue distances obtained from NMR structures of holo to apo transitions in calmodulin. Although unconstrained all-atom Cartesian simulations have failed to sample transitions between the substates of fasciculin and calmodulin, GNEIMO simulations show the transitions in both systems. The relatively short simulation times required to capture these long-timescale conformational dynamics indicate that GNEIMO is a promising molecular-dynamics technique for studying domain motion in

  19. Relating the dynamics of climatological and hydrological droughts in semiarid Botswana

    NASA Astrophysics Data System (ADS)

    Byakatonda, Jimmy; Parida, B. P.; Kenabatho, Piet K.

    2018-06-01

    Dynamics of droughts have been an associated feature of climate variability particularly in semiarid regions which impact on the response of hydrological systems. This study attempts to determine drought timescale that is suitable for monitoring the effects of drought on hydrological systems which can then be used to assess the long term persistence or reversion and forecasts of the dynamics. Based on this, climatological and hydrological drought indices characterized by Standardized precipitation evapotranspiration index (SPEI) and Standardized flow index (SFI) respectively have been determined using monthly rainfall, temperature and flow data from two major river systems. The association between climatological and hydrological droughts in Botswana has been investigated using these river systems namely: Okavango that is predominantly a storage type and Limpopo which is non-storage for a period of 1975-2014. Dynamics of climatological and hydrological droughts are showing trends towards drying conditions at both river systems. It was also observed that hydrological droughts lag climatological droughts by 7 months in Limpopo and 6 months in Okavango river systems respectively. Analyses of the association between climatic and flow indices indicate that the degree of association becomes stronger with increasing timescale at the Okavango river system. However in the Limpopo river system, it was observed that high timescales of 18- and 24-months were not useful in drought monitoring. 15-months timescale was identified to best monitor drought dynamics at both locations. Therefore SPEIs and SFIs computed at 15-months timescale have been used to assess the variability and long term persistence in drought dynamics through rescaled range analysis (R/S). H-coefficients of 0.06 and 0.08 resulted for Limpopo and Okavango respectively. These H-coefficients being significantly less than 0.5 is an indication of high variability and suggests a change in dynamics from the existing

  20. Special considerations for qualifying thin films for super pressure pumpkin ultra long duration balloon missions

    NASA Astrophysics Data System (ADS)

    Said, Magdi A.

    2004-01-01

    The assessment of creep and dynamic response behaviors on materials intended for ultra long duration balloon (ULDB) applications is essential. The first provides needed information for design and fabrication. The second ensures that the film is sufficiently tough to survive the dynamic events during launch and ascent. Characterization and assessment of these two important parameters are discussed in this paper. Visco-elastic behavior of materials in a loaded structure, such as the ULDB film change their geometry significantly over time under load causing possible changes in the load path and the stress distribution. These changes must be held in check to satisfy the functional requirements of the structure over its service life. Typically, the balloon experiences during its service life various environmental conditions each with a different creep response. These are characterized by a simplified load temperature history for the purpose of lifetime response assessment. At mid-latitudes a significant portion of the service life is spent at night, i.e., at low temperature and low load; for the ULDB film this night-time contribution to creep is negligible. By contrast, flight exposure in an Antarctic summer is at an almost constant high temperature and corresponding high pressure. This paper presents the creep behavior of the ULDB film as a function of load, temperature, and time along with an overview of its implementation in the design. In addition, it presents a quantitative assessment on the toughness of the material under dynamic "Snatch" loading.

  1. Mitigating and monitoring flight crew fatigue on a westward ultra-long-range flight.

    PubMed

    Signal, T Leigh; Mulrine, Hannah M; van den Berg, Margo J; Smith, Alexander A T; Gander, Philippa H; Serfontein, Wynand

    2014-12-01

    This study examined the uptake and effectiveness of fatigue mitigation guidance material including sleep recommendations for a trip with a westward ultra-long-range flight and return long-range flight. There were 52 flight crew (4-pilot crews, mean age 55 yr) who completed a sleep/duty diary and wore an actigraph prior to, during, and after the trip. Primary crew flew the takeoff and landing, while relief crew flew the aircraft during the Primary crew's breaks. At key times in flight, crewmembers rated their fatigue (Samn-Perelli fatigue scale) and sleepiness (Karolinska Sleepiness Scale) and completed a 5-min Psychomotor Vigilance Task. Napping was common prior to the outbound flight (54%) and did not affect the quantity or quality of in-flight sleep (mean 4.3 h). Primary crew obtained a similar amount on the inbound flight (mean 4.0 h), but Secondary crew had less sleep (mean 2.9 h). Subjective fatigue and sleepiness increased and performance slowed across flights. Performance was faster on the outbound than inbound flight. On both flights, Primary crew were less fatigued and sleepy than Secondary crew, particularly at top of descent and after landing. Crewmembers slept more frequently and had more sleep in the first 24 h of the layover than the last, and had shifted their main sleep to the local night by the second night. The suggested sleep mitigations were employed by the majority of crewmembers. Fatigue levels were no worse on the outbound ultra-long-range flight than on the return long-range flight.

  2. The estimation of dynamic contact angle of ultra-hydrophobic surfaces using inclined surface and impinging droplet methods

    NASA Astrophysics Data System (ADS)

    Jasikova, Darina; Kotek, Michal

    2014-03-01

    The development of industrial technology also brings with optimized surface quality, particularly where there is contact with food. Application ultra-hydrophobic surface significantly reduces the growth of bacteria and facilitates cleaning processes. Testing and evaluation of surface quality are used two methods: impinging droplet and inclined surface method optimized with high speed shadowgraphy, which give information about dynamic contact angle. This article presents the results of research into new methods of measuring ultra-hydrophobic patented technology.

  3. The Design of an Ultra High Capacity Long Range Transport Aircraft

    NASA Technical Reports Server (NTRS)

    Weisshaar, Terrence A.; Bucci, Gregory; Hare, Angela; Szolwinski, Matthew

    1993-01-01

    This paper examines the design of a 650 passenger aircraft with 8000 nautical mile range to reduce seat mile cost and to reduce airport and airway congestion. This design effort involves the usual issues that require trades between technologies, but must also include consideration of: airport terminal facilities; passenger loading and unloading; and, defeating the 'square-cube' law to design large structures. This paper will review the long range ultra high capacity or megatransport design problem and the variety of solutions developed by senior student design teams at Purdue University.

  4. Floquet–Magnus theory and generic transient dynamics in periodically driven many-body quantum systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kuwahara, Tomotaka, E-mail: tomotaka.phys@gmail.com; WPI, Advanced Institute for Materials Research, Tohoku University, Sendai 980-8577; Mori, Takashi

    2016-04-15

    This work explores a fundamental dynamical structure for a wide range of many-body quantum systems under periodic driving. Generically, in the thermodynamic limit, such systems are known to heat up to infinite temperature states in the long-time limit irrespective of dynamical details, which kills all the specific properties of the system. In the present study, instead of considering infinitely long-time scale, we aim to provide a general framework to understand the long but finite time behavior, namely the transient dynamics. In our analysis, we focus on the Floquet–Magnus (FM) expansion that gives a formal expression of the effective Hamiltonian onmore » the system. Although in general the full series expansion is not convergent in the thermodynamics limit, we give a clear relationship between the FM expansion and the transient dynamics. More precisely, we rigorously show that a truncated version of the FM expansion accurately describes the exact dynamics for a certain time-scale. Our theory reveals an experimental time-scale for which non-trivial dynamical phenomena can be reliably observed. We discuss several dynamical phenomena, such as the effect of small integrability breaking, efficient numerical simulation of periodically driven systems, dynamical localization and thermalization. Especially on thermalization, we discuss a generic scenario on the prethermalization phenomenon in periodically driven systems. -- Highlights: •A general framework to describe transient dynamics for periodically driven systems. •The theory is applicable to generic quantum many-body systems including long-range interacting systems. •Physical meaning of the truncation of the Floquet–Magnus expansion is rigorously established. •New mechanism of the prethermalization is proposed. •Revealing an experimental time-scale for which non-trivial dynamical phenomena can be reliably observed.« less

  5. Genomics of parallel adaptation at two timescales in Drosophila

    PubMed Central

    Begun, David J.

    2017-01-01

    Two interesting unanswered questions are the extent to which both the broad patterns and genetic details of adaptive divergence are repeatable across species, and the timescales over which parallel adaptation may be observed. Drosophila melanogaster is a key model system for population and evolutionary genomics. Findings from genetics and genomics suggest that recent adaptation to latitudinal environmental variation (on the timescale of hundreds or thousands of years) associated with Out-of-Africa colonization plays an important role in maintaining biological variation in the species. Additionally, studies of interspecific differences between D. melanogaster and its sister species D. simulans have revealed that a substantial proportion of proteins and amino acid residues exhibit adaptive divergence on a roughly few million years long timescale. Here we use population genomic approaches to attack the problem of parallelism between D. melanogaster and a highly diverged conger, D. hydei, on two timescales. D. hydei, a member of the repleta group of Drosophila, is similar to D. melanogaster, in that it too appears to be a recently cosmopolitan species and recent colonizer of high latitude environments. We observed parallelism both for genes exhibiting latitudinal allele frequency differentiation within species and for genes exhibiting recurrent adaptive protein divergence between species. Greater parallelism was observed for long-term adaptive protein evolution and this parallelism includes not only the specific genes/proteins that exhibit adaptive evolution, but extends even to the magnitudes of the selective effects on interspecific protein differences. Thus, despite the roughly 50 million years of time separating D. melanogaster and D. hydei, and despite their considerably divergent biology, they exhibit substantial parallelism, suggesting the existence of a fundamental predictability of adaptive evolution in the genus. PMID:28968391

  6. Decoding Intention at Sensorimotor Timescales

    PubMed Central

    Salvaris, Mathew; Haggard, Patrick

    2014-01-01

    The ability to decode an individual's intentions in real time has long been a ‘holy grail’ of research on human volition. For example, a reliable method could be used to improve scientific study of voluntary action by allowing external probe stimuli to be delivered at different moments during development of intention and action. Several Brain Computer Interface applications have used motor imagery of repetitive actions to achieve this goal. These systems are relatively successful, but only if the intention is sustained over a period of several seconds; much longer than the timescales identified in psychophysiological studies for normal preparation for voluntary action. We have used a combination of sensorimotor rhythms and motor imagery training to decode intentions in a single-trial cued-response paradigm similar to those used in human and non-human primate motor control research. Decoding accuracy of over 0.83 was achieved with twelve participants. With this approach, we could decode intentions to move the left or right hand at sub-second timescales, both for instructed choices instructed by an external stimulus and for free choices generated intentionally by the participant. The implications for volition are considered. PMID:24523855

  7. Ultra-low power wireless sensing for long-term structural health monitoring

    NASA Astrophysics Data System (ADS)

    Bilbao, Argenis; Hoover, Davis; Rice, Jennifer; Chapman, Jamie

    2011-04-01

    Researchers have made significant progress in recent years towards realizing long-term structural health monitoring (SHM) utilizing wireless smart sensor networks (WSSNs). These efforts have focused on improving the performance and robustness of such networks to achieve high quality data acquisition and in-network processing. One of the primary challenges still facing the use of smart sensors for long-term monitoring deployments is their limited power resources. Periodically accessing the sensor nodes to change batteries is not feasible or economical in many deployment cases. While energy harvesting techniques show promise for prolonging unattended network life, low-power design and operation are still critically important. This research presents a new, fully integrated ultra-low power wireless smart sensor node and a flexible base station, both designed for long-term SHM applications. The power consumption of the sensor nodes and base station has been minimized through careful hardware selection and the implementation of power-aware network software, without sacrificing flexibility and functionality.

  8. Timescales of quartz crystallization and the longevity of the Bishop giant magma body.

    PubMed

    Gualda, Guilherme A R; Pamukcu, Ayla S; Ghiorso, Mark S; Anderson, Alfred T; Sutton, Stephen R; Rivers, Mark L

    2012-01-01

    Supereruptions violently transfer huge amounts (100 s-1000 s km(3)) of magma to the surface in a matter of days and testify to the existence of giant pools of magma at depth. The longevity of these giant magma bodies is of significant scientific and societal interest. Radiometric data on whole rocks, glasses, feldspar and zircon crystals have been used to suggest that the Bishop Tuff giant magma body, which erupted ~760,000 years ago and created the Long Valley caldera (California), was long-lived (>100,000 years) and evolved rather slowly. In this work, we present four lines of evidence to constrain the timescales of crystallization of the Bishop magma body: (1) quartz residence times based on diffusional relaxation of Ti profiles, (2) quartz residence times based on the kinetics of faceting of melt inclusions, (3) quartz and feldspar crystallization times derived using quartz+feldspar crystal size distributions, and (4) timescales of cooling and crystallization based on thermodynamic and heat flow modeling. All of our estimates suggest quartz crystallization on timescales of <10,000 years, more typically within 500-3,000 years before eruption. We conclude that large-volume, crystal-poor magma bodies are ephemeral features that, once established, evolve on millennial timescales. We also suggest that zircon crystals, rather than recording the timescales of crystallization of a large pool of crystal-poor magma, record the extended periods of time necessary for maturation of the crust and establishment of these giant magma bodies.

  9. Advances in molecular dynamics simulation of ultra-precision machining of hard and brittle materials

    NASA Astrophysics Data System (ADS)

    Guo, Xiaoguang; Li, Qiang; Liu, Tao; Kang, Renke; Jin, Zhuji; Guo, Dongming

    2017-03-01

    Hard and brittle materials, such as silicon, SiC, and optical glasses, are widely used in aerospace, military, integrated circuit, and other fields because of their excellent physical and chemical properties. However, these materials display poor machinability because of their hard and brittle properties. Damages such as surface micro-crack and subsurface damage often occur during machining of hard and brittle materials. Ultra-precision machining is widely used in processing hard and brittle materials to obtain nanoscale machining quality. However, the theoretical mechanism underlying this method remains unclear. This paper provides a review of present research on the molecular dynamics simulation of ultra-precision machining of hard and brittle materials. The future trends in this field are also discussed.

  10. Long-range transport of black carbon to the Pacific Ocean and its dependence on aging timescale

    NASA Astrophysics Data System (ADS)

    Zhang, J.; Liu, J.; Tao, S.; Ban-Weiss, G. A.

    2015-10-01

    Improving the ability of global models to predict concentrations of black carbon (BC) over the Pacific Ocean is essential to evaluate the impact of BC on marine climate. In this study, we tag BC tracers from 13 source regions around the globe in a global chemical transport model, Model for Ozone and Related Chemical Tracers, version 4 (MOZART-4). Numerous sensitivity simulations are carried out varying the aging timescale of BC emitted from each source region. The aging timescale for each source region is optimized by minimizing errors in vertical profiles of BC mass mixing ratios between simulations and HIAPER Pole-to-Pole Observations (HIPPO). For most HIPPO deployments, in the Northern Hemisphere, optimized aging timescales are less than half a day for BC emitted from tropical and midlatitude source regions and about 1 week for BC emitted from high-latitude regions in all seasons except summer. We find that East Asian emissions contribute most to the BC loading over the North Pacific, while South American, African and Australian emissions dominate BC loadings over the South Pacific. Dominant source regions contributing to BC loadings in other parts of the globe are also assessed. The lifetime of BC originating from East Asia (i.e., the world's largest BC emitter) is found to be only 2.2 days, much shorter than the global average lifetime of 4.9 days, making the contribution from East Asia to the global BC burden only 36 % of that from the second largest emitter, Africa. Thus, evaluating only relative emission rates without accounting for differences in aging timescales and deposition rates is not predictive of the contribution of a given source region to climate impacts. Our simulations indicate that the lifetime of BC increases nearly linearly with aging timescale for all source regions. When the aging rate is fast, the lifetime of BC is largely determined by factors that control local deposition rates (e.g., precipitation). The sensitivity of lifetime to aging

  11. Timescales for determining temperature and dissolved oxygen trends in the Long Island Sound (LIS) estuary

    NASA Astrophysics Data System (ADS)

    Staniec, Allison; Vlahos, Penny

    2017-12-01

    Long-term time series represent a critical part of the oceanographic community's efforts to discern natural and anthropogenically forced variations in the environment. They provide regular measurements of climate relevant indicators including temperature, oxygen concentrations, and salinity. When evaluating time series, it is essential to isolate long-term trends from autocorrelation in data and noise due to natural variability. Herein we apply a statistical approach, well-established in atmospheric time series, to key parameters in the U.S. east coast's Long Island Sound estuary (LIS). Analysis shows that the LIS time series (established in the early 1990s) is sufficiently long to detect significant trends in physical-chemical parameters including temperature (T) and dissolved oxygen (DO). Over the last two decades, overall (combined surface and deep) LIS T has increased at an average rate of 0.08 ± 0.03 °C yr-1 while overall DO has dropped at an average rate of 0.03 ± 0.01 mg L-1yr-1 since 1994 at the 95% confidence level. This trend is notably faster than the global open ocean T trend (0.01 °C yr-1), as might be expected for a shallower estuarine system. T and DO trends were always significant for the existing time series using four month data increments. Rates of change of DO and T in LIS are strongly correlated and the rate of decrease of DO concentrations is consistent with the expected reduced solubility of DO at these higher temperatures. Thus, changes in T alone, across decadal timescales can account for between 33 and 100% of the observed decrease in DO. This has significant implications for other dissolved gases and the long-term management of LIS hypoxia.

  12. Coherent Timescales and Mechanical Structure of Multicellular Aggregates.

    PubMed

    Yu, Miao; Mahtabfar, Aria; Beelen, Paul; Demiryurek, Yasir; Shreiber, David I; Zahn, Jeffrey D; Foty, Ramsey A; Liu, Liping; Lin, Hao

    2018-06-05

    Multicellular aggregates are an excellent model system to explore the role of tissue biomechanics in specifying multicellular reorganization during embryonic developments and malignant invasion. Tissue-like spheroids, when subjected to a compressive force, are known to exhibit liquid-like behaviors at long timescales (hours), largely because of cell rearrangements that serve to effectively dissipate the applied stress. At short timescales (seconds to minutes), before cell rearrangement, the mechanical behavior is strikingly different. The current work uses shape relaxation to investigate the structural characteristics of aggregates and discovers two coherent timescales: one on the order of seconds, the other tens of seconds. These timescales are universal, conserved across a variety of tested species, and persist despite great differences in other properties such as tissue surface tension and adhesion. A precise mathematical theory is used to correlate the timescales with mechanical properties and reveals that aggregates have a relatively strong envelope and an unusually "soft" interior (weak bulk elastic modulus). This characteristic is peculiar, considering that both layers consist of identical units (cells), but is consistent with the fact that this structure can engender both structural integrity and the flexibility required for remodeling. In addition, tissue surface tension, elastic modulus, and viscosity are proportional to each other. Considering that these tissue-level properties intrinsically derive from cellular-level properties, the proportionalities imply precise coregulation of the latter and in particular of the tension on the cell-medium and cell-cell interfaces. Copyright © 2018 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  13. Neuronal long-range temporal correlations and avalanche dynamics are correlated with behavioral scaling laws

    PubMed Central

    Palva, J. Matias; Zhigalov, Alexander; Hirvonen, Jonni; Korhonen, Onerva; Linkenkaer-Hansen, Klaus; Palva, Satu

    2013-01-01

    Scale-free fluctuations are ubiquitous in behavioral performance and neuronal activity. In time scales from seconds to hundreds of seconds, psychophysical dynamics and the amplitude fluctuations of neuronal oscillations are governed by power-law-form long-range temporal correlations (LRTCs). In millisecond time scales, neuronal activity comprises cascade-like neuronal avalanches that exhibit power-law size and lifetime distributions. However, it remains unknown whether these neuronal scaling laws are correlated with those characterizing behavioral performance or whether neuronal LRTCs and avalanches are related. Here, we show that the neuronal scaling laws are strongly correlated both with each other and with behavioral scaling laws. We used source reconstructed magneto- and electroencephalographic recordings to characterize the dynamics of ongoing cortical activity. We found robust power-law scaling in neuronal LRTCs and avalanches in resting-state data and during the performance of audiovisual threshold stimulus detection tasks. The LRTC scaling exponents of the behavioral performance fluctuations were correlated with those of concurrent neuronal avalanches and LRTCs in anatomically identified brain systems. The behavioral exponents also were correlated with neuronal scaling laws derived from a resting-state condition and with a similar anatomical topography. Finally, despite the difference in time scales, the scaling exponents of neuronal LRTCs and avalanches were strongly correlated during both rest and task performance. Thus, long and short time-scale neuronal dynamics are related and functionally significant at the behavioral level. These data suggest that the temporal structures of human cognitive fluctuations and behavioral variability stem from the scaling laws of individual and intrinsic brain dynamics. PMID:23401536

  14. Timescale Correlation between Marine Atmospheric Exposure and Accelerated Corrosion Testing - Part 2

    NASA Technical Reports Server (NTRS)

    Montgomery, Eliza L.; Calle, Luz Marina; Curran, Jerome C.; Kolody, Mark R.

    2012-01-01

    Evaluation of metals to predict service life of metal-based structures in corrosive environments has long relied on atmospheric exposure test sites. Traditional accelerated corrosion testing relies on mimicking the exposure conditions, often incorporating salt spray and ultraviolet (UV) radiation, and exposing the metal to continuous or cyclic conditions similar to those of the corrosive environment. Their reliability to correlate to atmospheric exposure test results is often a concern when determining the timescale to which the accelerated tests can be related. Accelerated corrosion testing has yet to be universally accepted as a useful tool in predicting the long-term service life of a metal, despite its ability to rapidly induce corrosion. Although visual and mass loss methods of evaluating corrosion are the standard, and their use is crucial, a method that correlates timescales from accelerated testing to atmospheric exposure would be very valuable. This paper presents work that began with the characterization of the atmospheric environment at the Kennedy Space Center (KSC) Beachside Corrosion Test Site. The chemical changes that occur on low carbon steel, during atmospheric and accelerated corrosion conditions, were investigated using surface chemistry analytical methods. The corrosion rates and behaviors of panels subjected to long-term and accelerated corrosion conditions, involving neutral salt fog and alternating seawater spray, were compared to identify possible timescale correlations between accelerated and long-term corrosion performance. The results, as well as preliminary findings on the correlation investigation, are presented.

  15. Relationship between sea level and climate forcing by CO2 on geological timescales

    PubMed Central

    Foster, Gavin L.; Rohling, Eelco J.

    2013-01-01

    On 103- to 106-year timescales, global sea level is determined largely by the volume of ice stored on land, which in turn largely reflects the thermal state of the Earth system. Here we use observations from five well-studied time slices covering the last 40 My to identify a well-defined and clearly sigmoidal relationship between atmospheric CO2 and sea level on geological (near-equilibrium) timescales. This strongly supports the dominant role of CO2 in determining Earth’s climate on these timescales and suggests that other variables that influence long-term global climate (e.g., topography, ocean circulation) play a secondary role. The relationship between CO2 and sea level we describe portrays the “likely” (68% probability) long-term sea-level response after Earth system adjustment over many centuries. Because it appears largely independent of other boundary condition changes, it also may provide useful long-range predictions of future sea level. For instance, with CO2 stabilized at 400–450 ppm (as required for the frequently quoted “acceptable warming” of 2 °C), or even at AD 2011 levels of 392 ppm, we infer a likely (68% confidence) long-term sea-level rise of more than 9 m above the present. Therefore, our results imply that to avoid significantly elevated sea level in the long term, atmospheric CO2 should be reduced to levels similar to those of preindustrial times. PMID:23292932

  16. An ultra-high input impedance ECG amplifier for long-term monitoring of athletes.

    PubMed

    Gargiulo, Gaetano; Bifulco, Paolo; Cesarelli, Mario; Ruffo, Mariano; Romano, Maria; Calvo, Rafael A; Jin, Craig; van Schaik, André

    2010-01-01

    We present a new, low-power electrocardiogram (ECG) recording system with an ultra-high input impedance that enables the use of long-lasting, dry electrodes. The system incorporates a low-power Bluetooth module for wireless connectivity and is designed to be suitable for long-term monitoring during daily activities. The new system using dry electrodes was compared with a clinically approved ECG reference system using gelled Ag/AgCl electrodes and performance was found to be equivalent. In addition, the system was used to monitor an athlete during several physical tasks, and a good quality ECG was obtained in all cases, including when the athlete was totally submerged in fresh water.

  17. Mapping conformational dynamics of proteins using torsional dynamics simulations.

    PubMed

    Gangupomu, Vamshi K; Wagner, Jeffrey R; Park, In-Hee; Jain, Abhinandan; Vaidehi, Nagarajan

    2013-05-07

    All-atom molecular dynamics simulations are widely used to study the flexibility of protein conformations. However, enhanced sampling techniques are required for simulating protein dynamics that occur on the millisecond timescale. In this work, we show that torsional molecular dynamics simulations enhance protein conformational sampling by performing conformational search in the low-frequency torsional degrees of freedom. In this article, we use our recently developed torsional-dynamics method called Generalized Newton-Euler Inverse Mass Operator (GNEIMO) to study the conformational dynamics of four proteins. We investigate the use of the GNEIMO method in simulations of the conformationally flexible proteins fasciculin and calmodulin, as well as the less flexible crambin and bovine pancreatic trypsin inhibitor. For the latter two proteins, the GNEIMO simulations with an implicit-solvent model reproduced the average protein structural fluctuations and sample conformations similar to those from Cartesian simulations with explicit solvent. The application of GNEIMO with replica exchange to the study of fasciculin conformational dynamics produced sampling of two of this protein's experimentally established conformational substates. Conformational transition of calmodulin from the Ca(2+)-bound to the Ca(2+)-free conformation occurred readily with GNEIMO simulations. Moreover, the GNEIMO method generated an ensemble of conformations that satisfy about half of both short- and long-range interresidue distances obtained from NMR structures of holo to apo transitions in calmodulin. Although unconstrained all-atom Cartesian simulations have failed to sample transitions between the substates of fasciculin and calmodulin, GNEIMO simulations show the transitions in both systems. The relatively short simulation times required to capture these long-timescale conformational dynamics indicate that GNEIMO is a promising molecular-dynamics technique for studying domain motion in

  18. Hindcasting of decadal‐timescale estuarine bathymetric change with a tidal‐timescale model

    USGS Publications Warehouse

    Ganju, Neil K.; Schoellhamer, David H.; Jaffe, Bruce E.

    2009-01-01

    Hindcasting decadal-timescale bathymetric change in estuaries is prone to error due to limited data for initial conditions, boundary forcing, and calibration; computational limitations further hinder efforts. We developed and calibrated a tidal-timescale model to bathymetric change in Suisun Bay, California, over the 1867–1887 period. A general, multiple-timescale calibration ensured robustness over all timescales; two input reduction methods, the morphological hydrograph and the morphological acceleration factor, were applied at the decadal timescale. The model was calibrated to net bathymetric change in the entire basin; average error for bathymetric change over individual depth ranges was 37%. On a model cell-by-cell basis, performance for spatial amplitude correlation was poor over the majority of the domain, though spatial phase correlation was better, with 61% of the domain correctly indicated as erosional or depositional. Poor agreement was likely caused by the specification of initial bed composition, which was unknown during the 1867–1887 period. Cross-sectional bathymetric change between channels and flats, driven primarily by wind wave resuspension, was modeled with higher skill than longitudinal change, which is driven in part by gravitational circulation. The accelerated response of depth may have prevented gravitational circulation from being represented properly. As performance criteria became more stringent in a spatial sense, the error of the model increased. While these methods are useful for estimating basin-scale sedimentation changes, they may not be suitable for predicting specific locations of erosion or deposition. They do, however, provide a foundation for realistic estuarine geomorphic modeling applications.

  19. Timescales of Quartz Crystallization and the Longevity of the Bishop Giant Magma Body

    PubMed Central

    Gualda, Guilherme A. R.; Pamukcu, Ayla S.; Ghiorso, Mark S.; Anderson, Alfred T.; Sutton, Stephen R.; Rivers, Mark L.

    2012-01-01

    Supereruptions violently transfer huge amounts (100 s–1000 s km3) of magma to the surface in a matter of days and testify to the existence of giant pools of magma at depth. The longevity of these giant magma bodies is of significant scientific and societal interest. Radiometric data on whole rocks, glasses, feldspar and zircon crystals have been used to suggest that the Bishop Tuff giant magma body, which erupted ∼760,000 years ago and created the Long Valley caldera (California), was long-lived (>100,000 years) and evolved rather slowly. In this work, we present four lines of evidence to constrain the timescales of crystallization of the Bishop magma body: (1) quartz residence times based on diffusional relaxation of Ti profiles, (2) quartz residence times based on the kinetics of faceting of melt inclusions, (3) quartz and feldspar crystallization times derived using quartz+feldspar crystal size distributions, and (4) timescales of cooling and crystallization based on thermodynamic and heat flow modeling. All of our estimates suggest quartz crystallization on timescales of <10,000 years, more typically within 500–3,000 years before eruption. We conclude that large-volume, crystal-poor magma bodies are ephemeral features that, once established, evolve on millennial timescales. We also suggest that zircon crystals, rather than recording the timescales of crystallization of a large pool of crystal-poor magma, record the extended periods of time necessary for maturation of the crust and establishment of these giant magma bodies. PMID:22666359

  20. Timescales of Quartz Crystallization and the Longevity of the Bishop Giant Magma Body

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gualda, Guilherme A.R.; Pamukcu, Ayla S.; Ghiorso, Mark S.

    Supereruptions violently transfer huge amounts (100 s-1000 s km{sup 3}) of magma to the surface in a matter of days and testify to the existence of giant pools of magma at depth. The longevity of these giant magma bodies is of significant scientific and societal interest. Radiometric data on whole rocks, glasses, feldspar and zircon crystals have been used to suggest that the Bishop Tuff giant magma body, which erupted {approx}760,000 years ago and created the Long Valley caldera (California), was long-lived (>100,000 years) and evolved rather slowly. In this work, we present four lines of evidence to constrain themore » timescales of crystallization of the Bishop magma body: (1) quartz residence times based on diffusional relaxation of Ti profiles, (2) quartz residence times based on the kinetics of faceting of melt inclusions, (3) quartz and feldspar crystallization times derived using quartz+feldspar crystal size distributions, and (4) timescales of cooling and crystallization based on thermodynamic and heat flow modeling. All of our estimates suggest quartz crystallization on timescales of <10,000 years, more typically within 500-3,000 years before eruption. We conclude that large-volume, crystal-poor magma bodies are ephemeral features that, once established, evolve on millennial timescales. We also suggest that zircon crystals, rather than recording the timescales of crystallization of a large pool of crystal-poor magma, record the extended periods of time necessary for maturation of the crust and establishment of these giant magma bodies.« less

  1. Convergence and reproducibility in molecular dynamics simulations of the DNA duplex d(GCACGAACGAACGAACGC).

    PubMed

    Galindo-Murillo, Rodrigo; Roe, Daniel R; Cheatham, Thomas E

    2015-05-01

    The structure and dynamics of DNA are critically related to its function. Molecular dynamics simulations augment experiment by providing detailed information about the atomic motions. However, to date the simulations have not been long enough for convergence of the dynamics and structural properties of DNA. Molecular dynamics simulations performed with AMBER using the ff99SB force field with the parmbsc0 modifications, including ensembles of independent simulations, were compared to long timescale molecular dynamics performed with the specialized Anton MD engine on the B-DNA structure d(GCACGAACGAACGAACGC). To assess convergence, the decay of the average RMSD values over longer and longer time intervals was evaluated in addition to assessing convergence of the dynamics via the Kullback-Leibler divergence of principal component projection histograms. These molecular dynamics simulations-including one of the longest simulations of DNA published to date at ~44μs-surprisingly suggest that the structure and dynamics of the DNA helix, neglecting the terminal base pairs, are essentially fully converged on the ~1-5μs timescale. We can now reproducibly converge the structure and dynamics of B-DNA helices, omitting the terminal base pairs, on the μs time scale with both the AMBER and CHARMM C36 nucleic acid force fields. Results from independent ensembles of simulations starting from different initial conditions, when aggregated, match the results from long timescale simulations on the specialized Anton MD engine. With access to large-scale GPU resources or the specialized MD engine "Anton" it is possible for a variety of molecular systems to reproducibly and reliably converge the conformational ensemble of sampled structures. This article is part of a Special Issue entitled: Recent developments of molecular dynamics. Copyright © 2014. Published by Elsevier B.V.

  2. Calculating the spatio-temporal variability of bedrock exposure on seasonal hydrograph timescales as a prerequisite to modeling bedrock river evolution

    NASA Astrophysics Data System (ADS)

    Hurst, A. A.; Anderson, R. S.; Tucker, G. E.

    2017-12-01

    Erosion of bedrock river channels exerts significant control on landscape evolution because it communicates climatic and tectonic signals across a landscape by setting the lower erosional boundaries for hillslopes. Hillslope erosion delivers sediment to the channels, which then either store or transport the sediment. At times of high storage, access to the bedrock floor of the channel is limited, inhibiting bedrock erosion. This affects the timescale of channel response to imposed base-level lowering, which in turn affects hillslope erosion. Because occasional exposure of the bedrock bed is a minimum prerequisite for bedrock erosion, we seek to understand the evolution of sediment cover, or scour history, with sufficient resolution to answer when and where the bed is exposed. The scour history at a site is governed by grain size, bed and channel morphology, sediment concentration in the water, and seasonal flow conditions (hydrograph). The transient nature of bedrock exposure during high-flow events implies that short-term sediment cover dynamics are important for predicting long-term bedrock incision rates. Models of channel profile evolution, or of landscape evolution, generally ignore evolution of sediment cover on the hydrograph timescale. To develop insight into the necessary and sufficient conditions for bedrock exposure followed by reburial, we have developed a 1-D model of the evolution of alluvial cover thickness in a long channel profile in response to a seasonal hydrograph. This model tracks erosion, deposition, and the concentration of sediment in the water column separately, and generates histories of scour and fill over the course of the hydrograph. We compare the model's predictions with net-scour measurements in tributaries of the Grand Canyon and with scour-chain and accelerometer measurements in the Cedar River, Washington. By addressing alluvial scour on short timescales, we acknowledge the processes required to allow bedrock incision and

  3. Broadband ultrafast nonlinear absorption and ultra-long exciton relaxation time of black phosphorus quantum dots.

    PubMed

    Chen, Runze; Zheng, Xin; Jiang, Tian

    2017-04-03

    Black phosphorus (BP) has recently attracted significant attention for its brilliant physical and chemical features. The remarkable strong light-matter interaction and tunable direct wide range band-gap make it an ideal candidate in various application regions, especially saturable absorbers. In this paper, ultrasmall black phosphorus quantum dots (BPQDs), a unique form of phosphorus nanostructures, with average size of 5.7 ± 0.8 nm are synthesized. Compared with BP nanosheets (BPNs) with similar thickness, the ultrafast nonlinear optical (NLO) absorption properties and excited carrier dynamics are investigated in wide spectra. Beyond the saturation absorption (SA), giant two photon absorption (TPA) is observed in BPQDs. BPQDs exhibit quite different excitation intensity and wavelength dependent nonlinear optical (NLO) response from BPNs, which is attributed to the quantum confinement and edge effects. The BPQDs show broadband photon-induced absorption (PIA) under the probe wavelength from 470 nm to 850 nm and a fast and a slow decay time are obtained as long as 92 ± 10 ps and 1100 ± 100 ps, respectively. The substantial independence for ultra-long time scales of pump intensity and temperature reveals that the carrier recombination mechanism may be attributed to a defect-assisted Auger capture process. These findings will help to develop optoelectronic and photonic devices operating in the infrared and visible wavelength region.

  4. Dynamical equivalence, the origin of the Galactic field stellar and binary population, and the initial radius-mass relation of embedded clusters

    NASA Astrophysics Data System (ADS)

    Belloni, Diogo; Kroupa, Pavel; Rocha-Pinto, Helio J.; Giersz, Mirek

    2018-03-01

    In order to allow a better understanding of the origin of Galactic field populations, dynamical equivalence of stellar-dynamical systems has been postulated by Kroupa and Belloni et al. to allow mapping of solutions of the initial conditions of embedded clusters such that they yield, after a period of dynamical processing, the Galactic field population. Dynamically equivalent systems are defined to initially and finally have the same distribution functions of periods, mass ratios and eccentricities of binary stars. Here, we search for dynamically equivalent clusters using the MOCCA code. The simulations confirm that dynamically equivalent solutions indeed exist. The result is that the solution space is next to identical to the radius-mass relation of Marks & Kroupa, ( r_h/pc )= 0.1^{+0.07}_{-0.04} ( M_ecl/M_{⊙} )^{0.13± 0.04}. This relation is in good agreement with the oIMF. This is achieved by applying a similar procedurebserved density of molecular cloud clumps. According to the solutions, the time-scale to reach dynamical equivalence is about 0.5 Myr which is, interestingly, consistent with the lifetime of ultra-compact H II regions and the time-scale needed for gas expulsion to be active in observed very young clusters as based on their dynamical modelling.

  5. On the spatial decorrelation of stochastic solar resource variability at long timescales

    DOE PAGES

    Perez, Marc J. R.; Fthenakis, Vasilis M.

    2015-05-16

    Understanding the spatial and temporal characteristics of solar resource variability is important because it helps inform the discussion surrounding the merits of geographic dispersion and subsequent electrical interconnection of photovoltaics as part of a portfolio of future solutions for coping with this variability. The unpredictable resource variability arising from the stochastic nature of meteorological phenomena (from the passage of clouds to the movement of weather systems) is of most concern for achieving high PV penetration because unlike the passage of seasons or the shift from day to night, the uncertainty makes planning a challenge. A suitable proxy for unpredictable solarmore » resource variability at any given location is the series of variations in the clearness index from one time period to the next because the clearness index is largely independent of the predictable influence of solar geometry. At timescales shorter than one day, the correlation between these variations in clearness index at pairs of distinct geographic locations decreases with spatial extent and with timescale. As the aggregate variability across N decorrelated locations decreases as 1/√N, identifying the distance required to achieve this decorrelation is critical to quantifying the expected reduction in variability from geographic dispersion.« less

  6. UltraSail CubeSat Solar Sail Flight Experiment

    NASA Technical Reports Server (NTRS)

    Carroll, David; Burton, Rodney; Coverstone, Victoria; Swenson, Gary

    2013-01-01

    UltraSail is a next-generation, highrisk, high-payoff sail system for the launch, deployment, stabilization, and control of very large (km2 class) solar sails enabling high payload mass fractions for interplanetary and deep space spacecraft. UltraSail is a non-traditional approach to propulsion technology achieved by combining propulsion and control systems developed for formation- flying microsatellites with an innovative solar sail architecture to achieve controllable sail areas approaching 1 km2, sail subsystem area densities approaching 1 g/m2, and thrust levels many times those of ion thrusters used for comparable deep space missions. UltraSail can achieve outer planetary rendezvous, a deep-space capability now reserved for high-mass nuclear and chemical systems. There is a twofold rationale behind the UltraSail concept for advanced solar sail systems. The first is that sail-andboom systems are inherently size-limited. The boom mass must be kept small, and column buckling limits the boom length to a few hundred meters. By eliminating the boom, UltraSail not only offers larger sail area, but also lower areal density, allowing larger payloads and shorter mission transit times. The second rationale for UltraSail is that sail films present deployment handling difficulties as the film thickness approaches one micrometer. The square sail requires that the film be folded in two directions for launch, and similarly unfolded for deployment. The film is stressed at the intersection of two folds, and this stress varies inversely with the film thickness. This stress can cause the film to yield, forming a permanent crease, or worse, to perforate. By rolling the film as UltraSail does, creases are prevented. Because the film is so thin, the roll thickness is small. Dynamic structural analysis of UltraSail coupled with dynamic control analysis shows that the system can be designed to eliminate longitudinal torsional waves created while controlling the pitch of the blades

  7. Generalized Green's function molecular dynamics for canonical ensemble simulations

    NASA Astrophysics Data System (ADS)

    Coluci, V. R.; Dantas, S. O.; Tewary, V. K.

    2018-05-01

    The need of small integration time steps (˜1 fs) in conventional molecular dynamics simulations is an important issue that inhibits the study of physical, chemical, and biological systems in real timescales. Additionally, to simulate those systems in contact with a thermal bath, thermostating techniques are usually applied. In this work, we generalize the Green's function molecular dynamics technique to allow simulations within the canonical ensemble. By applying this technique to one-dimensional systems, we were able to correctly describe important thermodynamic properties such as the temperature fluctuations, the temperature distribution, and the velocity autocorrelation function. We show that the proposed technique also allows the use of time steps one order of magnitude larger than those typically used in conventional molecular dynamics simulations. We expect that this technique can be used in long-timescale molecular dynamics simulations.

  8. Ultra-long fiber Raman lasers: design considerations

    NASA Astrophysics Data System (ADS)

    Koltchanov, I.; Kroushkov, D. I.; Richter, A.

    2015-03-01

    In frame of the European Marie Currie project GRIFFON [http://astonishgriffon.net/] the usage of a green approach in terms of reduced power consumption and maintenance costs is envisioned for long-span fiber networks. This shall be accomplished by coherent transmission in unrepeatered links (100 km - 350 km) utilizing ultra-long Raman fiber laser (URFL)-based distributed amplification, multi-level modulation formats, and adapted Digital Signal Processing (DSP) algorithms. The URFL uses a cascaded 2-order pumping scheme where two (co- and counter-) ˜ 1365 nm pumps illuminate the fiber. The URFL oscillates at ˜ 1450 nm whereas amplification is provided by stimulated Raman scattering (SRS) of the ˜ 1365 nm pumps and the optical feedback is realized by two Fiber Bragg gratings (FBGs) at the fiber ends reflecting at 1450 nm. The light field at 1450 nm provides amplification for signal waves in the 1550 nm range due to SRS. In this work we present URFL design studies intended to characterize and optimize the power and noise characteristics of the fiber links. We use a bidirectional fiber model describing propagation of the signal, pump and noise powers along the fiber length. From the numerical solution we evaluate the on/off Raman gain and its bandwidth, the signal excursion over the fiber length, OSNR spectra, and the accumulated nonlinearities. To achieve best performance for these characteristics the laser design is optimized with respect to the forward/backward pump powers and wavelengths, input/output signal powers, reflectivity profile of the FBGs and other parameters.

  9. Bringing global gyrokinetic turbulence simulations to the transport timescale using a multiscale approach

    NASA Astrophysics Data System (ADS)

    Parker, Jeffrey B.; LoDestro, Lynda L.; Told, Daniel; Merlo, Gabriele; Ricketson, Lee F.; Campos, Alejandro; Jenko, Frank; Hittinger, Jeffrey A. F.

    2018-05-01

    The vast separation dividing the characteristic times of energy confinement and turbulence in the core of toroidal plasmas makes first-principles prediction on long timescales extremely challenging. Here we report the demonstration of a multiple-timescale method that enables coupling global gyrokinetic simulations with a transport solver to calculate the evolution of the self-consistent temperature profile. This method, which exhibits resiliency to the intrinsic fluctuations arising in turbulence simulations, holds potential for integrating nonlocal gyrokinetic turbulence simulations into predictive, whole-device models.

  10. Floquet-Magnus theory and generic transient dynamics in periodically driven many-body quantum systems

    NASA Astrophysics Data System (ADS)

    Kuwahara, Tomotaka; Mori, Takashi; Saito, Keiji

    2016-04-01

    This work explores a fundamental dynamical structure for a wide range of many-body quantum systems under periodic driving. Generically, in the thermodynamic limit, such systems are known to heat up to infinite temperature states in the long-time limit irrespective of dynamical details, which kills all the specific properties of the system. In the present study, instead of considering infinitely long-time scale, we aim to provide a general framework to understand the long but finite time behavior, namely the transient dynamics. In our analysis, we focus on the Floquet-Magnus (FM) expansion that gives a formal expression of the effective Hamiltonian on the system. Although in general the full series expansion is not convergent in the thermodynamics limit, we give a clear relationship between the FM expansion and the transient dynamics. More precisely, we rigorously show that a truncated version of the FM expansion accurately describes the exact dynamics for a certain time-scale. Our theory reveals an experimental time-scale for which non-trivial dynamical phenomena can be reliably observed. We discuss several dynamical phenomena, such as the effect of small integrability breaking, efficient numerical simulation of periodically driven systems, dynamical localization and thermalization. Especially on thermalization, we discuss a generic scenario on the prethermalization phenomenon in periodically driven systems.

  11. Ultra-fast dynamics in the nonlinear optical response of silver nanoprism ordered arrays.

    PubMed

    Sánchez-Esquivel, Héctor; Raygoza-Sanchez, Karen Y; Rangel-Rojo, Raúl; Kalinic, Boris; Michieli, Niccolò; Cesca, Tiziana; Mattei, Giovanni

    2018-03-15

    In this work we present the study of the ultra-fast dynamics of the nonlinear optical response of a honeycomb array of silver triangular nanoprisms, performed using a femtosecond pulsed laser tuned with the dipolar surface plasmon resonance of the nanoarray. Nonlinear absorption and refraction, and their time-dependence, were explored using the z-scan and time-resolved excite-probe techniques. Nonlinear absorption is shown to change sign with the input irradiance and the behavior was explained on the basis of a three-level model. The response time was determined to be in the picosecond regime. A technique based on a variable frequency chopper was also used in order to discriminate the thermal and electronic contributions to the nonlinearity, which were found to have opposite signs. All these findings propel the investigated nanoprism arrays as good candidates for applications in advanced ultra-fast nonlinear nanophotonic devices.

  12. Perspectives for short timescale variability studies with Gaia

    NASA Astrophysics Data System (ADS)

    Roelens, M.; Eyer, L.; Mowlavi, N.; Lecoeur-Taïbi, I.; Rimoldini, L.; Blanco-Cuaresma, S.; Palaversa, L.; Süveges, M.; Charnas, J.; Wevers, T.

    2017-12-01

    We assess the potential of Gaia for detecting and characterizing short timescale variables, i.e. at timescale from a few seconds to a dozen hours, through extensive light-curve simulations for various short timescale variable types, including both periodic and non-periodic variability. We evidence that the variogram analysis applied to Gaia photometry should enable to detect such fast variability phenomena, down to amplitudes of a few millimagnitudes, with limited contamination from longer timescale variables or constant sources. This approach also gives valuable information on the typical timescale(s) of the considered variation, which could complement results of classical period search methods, and help prepare ground-based follow-up of the Gaia short timescale candidates.

  13. Advancing Atmospheric River Forecasts into Subseasonal-to-Seasonal Timescales

    NASA Astrophysics Data System (ADS)

    Barnes, E. A.; Baggett, C.; Mundhenk, B. D.; Nardi, K.; Maloney, E. D.

    2017-12-01

    Atmospheric rivers can cause considerable mayhem along the west coast of North America - delivering flooding rains during periods of heightened activity and desiccating droughts during periods of reduced activity. The intrinsic chaos of the atmosphere makes the prediction of atmospheric rivers at subseasonal-to-seasonal (S2S) timescales ( 2 to 6 weeks) an inherently difficult task. We demonstrate here that the potential exists to advance forecast lead times of atmospheric rivers into S2S timescales through knowledge of two of the atmosphere's most prominent oscillations; the Madden-Julian oscillation (MJO) and the Quasi-biennial oscillation (QBO). The dynamical relationship between atmospheric rivers, the MJO and the QBO is hypothesized to occur through modulation of North Pacific blocking. We present an empirical prediction scheme for anomalous atmospheric river activity based solely on the MJO and QBO and demonstrate skillful subseasonal "forecasts of opportunity" 5+ weeks ahead. We conclude with a discussion of the ability of state-of-the-art NWP models to predict atmospheric river characteristics on S2S timescales. With the wide-ranging impacts associated with landfalling atmospheric rivers, even modest gains in the subseasonal prediction of anomalous atmospheric river activity may support early action decision making and benefit numerous sectors of society.

  14. Convergence and reproducibility in molecular dynamics simulations of the DNA duplex d(GCACGAACGAACGAACGC)

    PubMed Central

    Galindo-Murillo, Rodrigo; Roe, Daniel R.; Cheatham, Thomas E.

    2014-01-01

    Background The structure and dynamics of DNA are critically related to its function. Molecular dynamics (MD) simulations augment experiment by providing detailed information about the atomic motions. However, to date the simulations have not been long enough for convergence of the dynamics and structural properties of DNA. Methods MD simulations performed with AMBER using the ff99SB force field with the parmbsc0 modifications, including ensembles of independent simulations, were compared to long timescale MD performed with the specialized Anton MD engine on the B-DNA structure d(GCACGAACGAACGAACGC). To assess convergence, the decay of the average RMSD values over longer and longer time intervals was evaluated in addition to assessing convergence of the dynamics via the Kullback-Leibler divergence of principal component projection histograms. Results These MD simulations —including one of the longest simulations of DNA published to date at ~44 μs—surprisingly suggest that the structure and dynamics of the DNA helix, neglecting the terminal base pairs, are essentially fully converged on the ~1–5 μs timescale. Conclusions We can now reproducibly converge the structure and dynamics of B-DNA helices, omitting the terminal base pairs, on the μs time scale with both the AMBER and CHARMM C36 nucleic acid force fields. Results from independent ensembles of simulations starting from different initial conditions, when aggregated, match the results from long timescale simulations on the specialized Anton MD engine. General Significance With access to large-scale GPU resources or the specialized MD engine “Anton” it is possibly for a variety of molecular systems to reproducibly and reliably converge the conformational ensemble of sampled structures. PMID:25219455

  15. The neural processing of hierarchical structure in music and speech at different timescales.

    PubMed

    Farbood, Morwaread M; Heeger, David J; Marcus, Gary; Hasson, Uri; Lerner, Yulia

    2015-01-01

    Music, like speech, is a complex auditory signal that contains structures at multiple timescales, and as such is a potentially powerful entry point into the question of how the brain integrates complex streams of information. Using an experimental design modeled after previous studies that used scrambled versions of a spoken story (Lerner et al., 2011) and a silent movie (Hasson et al., 2008), we investigate whether listeners perceive hierarchical structure in music beyond short (~6 s) time windows and whether there is cortical overlap between music and language processing at multiple timescales. Experienced pianists were presented with an extended musical excerpt scrambled at multiple timescales-by measure, phrase, and section-while measuring brain activity with functional magnetic resonance imaging (fMRI). The reliability of evoked activity, as quantified by inter-subject correlation of the fMRI responses, was measured. We found that response reliability depended systematically on musical structure coherence, revealing a topographically organized hierarchy of processing timescales. Early auditory areas (at the bottom of the hierarchy) responded reliably in all conditions. For brain areas at the top of the hierarchy, the original (unscrambled) excerpt evoked more reliable responses than any of the scrambled excerpts, indicating that these brain areas process long-timescale musical structures, on the order of minutes. The topography of processing timescales was analogous with that reported previously for speech, but the timescale gradients for music and speech overlapped with one another only partially, suggesting that temporally analogous structures-words/measures, sentences/musical phrases, paragraph/sections-are processed separately.

  16. Evidence for Long-Timescale Patterns of Synaptic Inputs in CA1 of Awake Behaving Mice.

    PubMed

    Kolb, Ilya; Talei Franzesi, Giovanni; Wang, Michael; Kodandaramaiah, Suhasa B; Forest, Craig R; Boyden, Edward S; Singer, Annabelle C

    2018-02-14

    Repeated sequences of neural activity are a pervasive feature of neural networks in vivo and in vitro In the hippocampus, sequential firing of many neurons over periods of 100-300 ms reoccurs during behavior and during periods of quiescence. However, it is not known whether the hippocampus produces longer sequences of activity or whether such sequences are restricted to specific network states. Furthermore, whether long repeated patterns of activity are transmitted to single cells downstream is unclear. To answer these questions, we recorded intracellularly from hippocampal CA1 of awake, behaving male mice to examine both subthreshold activity and spiking output in single neurons. In eight of nine recordings, we discovered long (900 ms) reoccurring subthreshold fluctuations or "repeats." Repeats generally were high-amplitude, nonoscillatory events reoccurring with 10 ms precision. Using statistical controls, we determined that repeats occurred more often than would be expected from unstructured network activity (e.g., by chance). Most spikes occurred during a repeat, and when a repeat contained a spike, the spike reoccurred with precision on the order of ≤20 ms, showing that long repeated patterns of subthreshold activity are strongly connected to spike output. Unexpectedly, we found that repeats occurred independently of classic hippocampal network states like theta oscillations or sharp-wave ripples. Together, these results reveal surprisingly long patterns of repeated activity in the hippocampal network that occur nonstochastically, are transmitted to single downstream neurons, and strongly shape their output. This suggests that the timescale of information transmission in the hippocampal network is much longer than previously thought. SIGNIFICANCE STATEMENT We found long (≥900 ms), repeated, subthreshold patterns of activity in CA1 of awake, behaving mice. These repeated patterns ("repeats") occurred more often than expected by chance and with 10 ms

  17. Development Overview of the Revised NASA Ultra Long Duration Balloon

    NASA Technical Reports Server (NTRS)

    Cathey, H. M.; Gregory, D; Young, L.; Pierce, D.

    2006-01-01

    The development of the National Aeronautics and Space Administration s (NASA) Ultra Long Duration Balloon (ULDB) has made significant strides in addressing the deployment issues experienced in the scaling up of the balloon structure. This paper concentrates on the super-pressure balloon developments that have been, and are currently being planned by the NASA Balloon Program Office at Goddard Space Flight Center s Wallops Flight Facility. The goal of the NASA ULDB development project is to attempt to extend the potential flight durations for large scientific balloon payloads. A summary of the February 2005 test flight from Ft. Sumner, New Mexico will be presented. This test flight spurred a number of investigations and advancements for this project. The development path has pursued some new approaches in the design, analysis, and testing of the balloons. New issues have been ideEti6ed throu& both analysis md testing. These have been addressed in the design stage before the next balloon construction was begun. This paper will give an overview of the recent history for this effort and the development approach pursued for ULDB. A description of the balloon design, including the modifications made as a result of the lessons learned, will be presented. Areas to be presented include the design approach, deployment issues that have been encountered and the proposed solutions, ground testing, photogrammetry, and an analysis overview. Test flight planning and considerations will be presented including test flight safety. An extended duration test flight of the National Aeronautics and Space Administration s Ultra Long Duration Balloon is planned for the May/June 2006 time frame. This flight is expected to fly from Sweden to either Canada or Alaska. Preliminary results of this flight will be presented as available. Future plans for both ground testing and additional test flights will also be presented. Goals of the future test flights, which are staged in increments of

  18. Long range surface plasmon resonance with ultra-high penetration depth for self-referenced sensing and ultra-low detection limit using diverging beam approach

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Isaacs, Sivan, E-mail: sivan.isaacs@gmail.com; Abdulhalim, Ibrahim; NEW CREATE Programme, School of Materials Science and Engineering, 1 CREATE Way, Research Wing, #02-06/08, Singapore 138602

    2015-05-11

    Using an insulator-metal-insulator structure with dielectric having refractive index (RI) larger than the analyte, long range surface plasmon (SP) resonance exhibiting ultra-high penetration depth is demonstrated for sensing applications of large bioentities at wavelengths in the visible range. Based on the diverging beam approach in Kretschmann-Raether configuration, one of the SP resonances is shown to shift in response to changes in the analyte RI while the other is fixed; thus, it can be used as a built in reference. The combination of the high sensitivity, high penetration depth and self-reference using the diverging beam approach in which a dark linemore » is detected of the high sensitivity, high penetration depth, self-reference, and the diverging beam approach in which a dark line is detected using large number of camera pixels with a smart algorithm for sub-pixel resolution, a sensor with ultra-low detection limit is demonstrated suitable for large bioentities.« less

  19. Gamma-ray burster recurrence timescales

    NASA Technical Reports Server (NTRS)

    Schaefer, B. E.; Cline, T. L.

    1984-01-01

    Three optical transients have been found which are associated with gamma-ray bursters (GRBs). The deduced recurrence timescale for these optical transients (tau sub opt) will depend on the minimum brightness for which a flash would be detected. A detailed analysis using all available data of tau sub opt as a function of E(gamma)/E(opt) is given. For flashes similar to those found in the Harvard archives, the best estimate of tau sub opt is 0.74 years, with a 99% confidence interval from 0.23 years to 4.7 years. It is currently unclear whether the optical transients from GRBs also give rise to gamma-ray events. One way to test this association is to measure the recurrence timescale of gamma-ray events tau sub gamma. A total of 210 gamma-ray error boxes were examined and it was found that the number of observed overlaps is not significantly different from the number expected from chance coincidence. This observation can be used to place limits on tau sub gamma for an assumed luminosity function. It was found that tau sub gamma is approx. 10 yr if bursts are monoenergetic. However, if GRBs have a power law luminosity function with a wide dynamic range, then the limit is tau sub gamma 0.5 yr. Hence, the gamma-ray data do not require tau sub gamma and tau sub opt to be different.

  20. Universal entanglement timescale for Rényi entropies

    NASA Astrophysics Data System (ADS)

    Cresswell, Jesse C.

    2018-02-01

    Recently it was shown that the growth of entanglement in an initially separable state, as measured by the purity of subsystems, can be characterized by a timescale that takes a universal form for any Hamiltonian. We show that the same timescale governs the growth of entanglement for all Rényi entropies. Since the family of Rényi entropies completely characterizes the entanglement of a pure bipartite state, our timescale is a universal feature of bipartite entanglement. The timescale depends only on the interaction Hamiltonian and the initial state.

  1. Use of a new ultra-long-range terrestrial LiDAR system to monitor the mass balance of very small glaciers in the Swiss Alps

    NASA Astrophysics Data System (ADS)

    Fischer, M.; Huss, M.; Hoelzle, M.

    2015-12-01

    Measuring glacier mass balance is important as it directly reflects the climatic forcing on the glacier surface. Today, repeated comparison of digital elevation models (DEMs) is a popular and widely used approach to derive surface elevation, volume and mass changes for a large number of glaciers. In high-mountain environments, airborne laser scanning (ALS) techniques currently provide the most accurate and highest resolution DEMs on the catchment scale, allowing the computation of glacier changes on an annual or even semi-annual basis. For monitoring individual glaciers though, terrestrial laser scanning (TLS) is easier and more cost-efficiently applied on the seasonal timescale compared to ALS. Since most recently, the application of the latest generation of ultra-long-range near infrared TLS systems allows the acquisition of surface elevation information over snow and ice of unprecedented quality and over larger zones than with previous near infrared TLS devices. Although very small glaciers represent the majority in number in most mountain ranges on Earth, their response to climatic changes is still not fully understood and field measurements are sparse. Therefore, a programme was set up in 2012 to monitor both the seasonal and annual surface mass balance of six very small glaciers across the Swiss Alps using the direct glaciological method. As often nearly the entire surface is visible from one single location, TLS is a highly promising technique to generate repeated high-resolution DEMs as well as to derive seasonal geodetic mass balances of very small ice masses. In this study, we present seasonal surface elevation, volume and geodetic mass changes for five very small glaciers in Switzerland (Glacier de Prapio, Glacier du Sex Rouge, St. Annafirn, Schwarzbachfirn and Pizolgletscher) derived from the comparison of seasonally repeated high-resolution DEMs acquired since autumn 2013 with the new ultra-long-range TLS device Riegl VZ-6000. We show the different

  2. Timescale differences between SC-PDSI and SPEI for drought monitoring in China

    NASA Astrophysics Data System (ADS)

    Zhao, Haiyan; Gao, Ge; An, Wei; Zou, Xukai; Li, Haitao; Hou, Meiting

    2017-12-01

    The Palmer Drought Severity Index (PDSI) has been widely used to monitor drought. Its characteristics are more suitable for measuring droughts of longer timescales, and this fact has not received much attention. The Standardized Precipitation Evapotranspiration Index (SPEI) can better reflect the climatic water balance, owing to its combination of precipitation and potential evapotranspiration. In this study, we selected monthly average air temperature and precipitation data from 589 meteorological stations of China's National Meteorological Information Center, to compare the effects of applying a self-calibrating PDSI (SC-PDSI) and SPEI to monitor drought events in the station regions, with a special focus on differences of event timescale. The results show the following. 1) Comparative analysis using SC-PDSI and SPEI for drought years and characters of three dry periods from 1961 to 2011 in the Beijing region showed that durations of SC-PDSI-based dry spells were longer than those of 3-month and 6-month SPEIs, but equal to those of 12-month or longer timescale SPEIs. 2) For monitoring evolution of the fall 2009 to spring 2010 Southwest China drought and spring 2000 Huang-Huai drought, 3-month SPEI could better monitor the initiation, aggravation, alleviation and relief of drought in the two regions, whereas the SC-PDSI was insensitive to drought recovery because of its long-term memory of previous climate conditions. 3) Analysis of the relationship between SC-PDSI for different regions and SPEI for different timescales showed that correlation of the two indexes changed with region, and SC-PDSI was maximally correlated with SPEI of 9-19 months in China. Therefore, SC-PDSI is only suitable for monitoring mid- and long-term droughts, owing to the strong lagged autocorrelation such as 0.4786 for 12-month lagged ones in Beijing, whereas SPEI is suitable for both short- and long-term drought-monitoring and should have greater application prospects in China.

  3. Timescales and bottlenecks in miRNA-dependent gene regulation.

    PubMed

    Hausser, Jean; Syed, Afzal Pasha; Selevsek, Nathalie; van Nimwegen, Erik; Jaskiewicz, Lukasz; Aebersold, Ruedi; Zavolan, Mihaela

    2013-12-03

    MiRNAs are post-transcriptional regulators that contribute to the establishment and maintenance of gene expression patterns. Although their biogenesis and decay appear to be under complex control, the implications of miRNA expression dynamics for the processes that they regulate are not well understood. We derived a mathematical model of miRNA-mediated gene regulation, inferred its parameters from experimental data sets, and found that the model describes well time-dependent changes in mRNA, protein and ribosome density levels measured upon miRNA transfection and induction. The inferred parameters indicate that the timescale of miRNA-dependent regulation is slower than initially thought. Delays in miRNA loading into Argonaute proteins and the slow decay of proteins relative to mRNAs can explain the typically small changes in protein levels observed upon miRNA transfection. For miRNAs to regulate protein expression on the timescale of a day, as miRNAs involved in cell-cycle regulation do, accelerated miRNA turnover is necessary.

  4. Ultra-long-period grating as a novel tool for multi-wavelength ultrafast photonics

    NASA Astrophysics Data System (ADS)

    Guo, Bo; Yang, Wen-Lei

    2017-10-01

    Here, we demonstrate the six-wavelength mode-locking and hybrid mode-locking operation in an erbium-doped fiber laser (EDFL) with an ultra-long-period grating (ULPG) by properly adjusting the pump power and the cavity parameters. The ULPG is fabricated by using the fused biconical method with a GPX-3000 glass processing system. Study found that, the ULPG exhibits dual-function, that is, mode-locker and multiwavelength filter. Our finding implies that apart from its fantastic sensing application, the ULPG may also possess attractive nonlinear optical property for ultrafast photonics.

  5. A facile route to ultra-long polyaniline nanowires and the fabrication of photoswitch.

    PubMed

    Wang, Xiuhua; Shao, Mingwang; Shao, Guang; Wu, Zhengcui; Wang, Shaowu

    2009-04-01

    Ultra-long polyaniline nanowires with an average diameter of 60 nm and length up to tens of micrometers were successfully synthesized via chemical oxidation polymerization in an aqueous solution. These nanowires exhibited reversible electrochemical behavior judged from cyclic voltammetry curves. The excellent photosensitivity and photoresponse of a bundle of nanowires were also investigated, which showed that the photocurrent enhanced by ca. 4 times under irradiation of an incandescence lamp (12 V, 10 W). This work might be useful in the fabrication of photosensor and photoswitch nanodevices in the future.

  6. An Acrobatic Substrate Metamorphosis Reveals a Requirement for Substrate Conformational Dynamics in Trypsin Proteolysis

    DOE PAGES

    Kayode, Olumide; Wang, Ruiying; Pendlebury, Devon F.; ...

    2016-11-03

    The molecular basis of enzyme catalytic power and specificity derives from dynamic interactions between enzyme and substrate during catalysis. While considerable effort has been devoted to understanding how conformational dynamics within enzymes affect catalysis, the role of conformational dynamics within protein substrates has not been addressed. Here in this paper, we examine the importance of substrate dynamics in the cleavage of Kunitz-BPTI protease inhibitors by mesotrypsin, finding that the varied conformational dynamics of structurally similar substrates can profoundly impact the rate of catalysis. A 1.4 Å crystal structure of a mesotrypsin-product complex formed with a rapidly cleaved substrate reveals amore » dramatic conformational change in the substrate upon proteolysis. Using long all-atom molecular dynamics simulations of acyl-enzyme intermediates with proteolysis rates spanning three orders of magnitude, we identify global and local dynamic features of substrates on the ns-μs timescale that correlate with enzymatic rates and explain differential susceptibility to proteolysis. By integrating multiple enhanced sampling methods for molecular dynamics, we model a viable conformational pathway between substratelike and product-like states, linking substrate dynamics on the ns-μs timescale with large collective substrate motions on the much slower timescale of catalysis. Our findings implicate substrate flexibility as a critical determinant of catalysis.« less

  7. Analysis of stationary fuel cell dynamic ramping capabilities and ultra capacitor energy storage using high resolution demand data

    NASA Astrophysics Data System (ADS)

    Meacham, James R.; Jabbari, Faryar; Brouwer, Jacob; Mauzey, Josh L.; Samuelsen, G. Scott

    Current high temperature fuel cell (HTFC) systems used for stationary power applications (in the 200-300 kW size range) have very limited dynamic load following capability or are simply base load devices. Considering the economics of existing electric utility rate structures, there is little incentive to increase HTFC ramping capability beyond 1 kWs -1 (0.4% s -1). However, in order to ease concerns about grid instabilities from utility companies and increase market adoption, HTFC systems will have to increase their ramping abilities, and will likely have to incorporate electrical energy storage (EES). Because batteries have low power densities and limited lifetimes in highly cyclic applications, ultra capacitors may be the EES medium of choice. The current analyses show that, because ultra capacitors have a very low energy storage density, their integration with HTFC systems may not be feasible unless the fuel cell has a ramp rate approaching 10 kWs -1 (4% s -1) when using a worst-case design analysis. This requirement for fast dynamic load response characteristics can be reduced to 1 kWs -1 by utilizing high resolution demand data to properly size ultra capacitor systems and through demand management techniques that reduce load volatility.

  8. Dynamic conductivity and plasmon profile of aluminum in the ultra-fast-matter regime

    NASA Astrophysics Data System (ADS)

    Dharma-wardana, M. W. C.

    2016-06-01

    We use an explicitly isochoric two-temperature theory to analyze recent x-ray laser scattering data for aluminum in the ultra-fast-matter (UFM) regime up to 6 eV. The observed surprisingly low conductivities are explained by including strong electron-ion scattering effects using the phase shifts calculated via the neutral-pseudo-atom model. The difference between the static conductivity for UFM-Al and equilibrium aluminum in the warm-dense matter state is clearly brought out by comparisons with available density-fucntional+molecular-dynamics simulations. Thus the applicability of the Mermin model to UFM is questioned. The static and dynamic conductivity, collision frequency, and the plasmon line shape, evaluated within the simplest Born approximation for UFM aluminum, are in good agreement with experiment.

  9. Timescale Correlation between Marine Atmospheric Exposure and Accelerated Corrosion Testing

    NASA Technical Reports Server (NTRS)

    Montgomery, Eliza L.; Calle, Luz Marina; Curran, Jerone C.; Kolody, Mark R.

    2011-01-01

    Evaluation of metal-based structures has long relied on atmospheric exposure test sites to determine corrosion resistance in marine environments. Traditional accelerated corrosion testing relies on mimicking the exposure conditions, often incorporating salt spray and ultraviolet (UV) radiation, and exposing the metal to continuous or cyclic conditions of the corrosive environment. Their success for correlation to atmospheric exposure is often a concern when determining the timescale to which the accelerated tests can be related. Accelerated laboratory testing, which often focuses on the electrochemical reactions that occur during corrosion conditions, has yet to be universally accepted as a useful tool in predicting the long term service life of a metal despite its ability to rapidly induce corrosion. Although visual and mass loss methods of evaluating corrosion are the standard and their use is imperative, a method that correlates timescales from atmospheric exposure to accelerated testing would be very valuable. This work uses surface chemistry to interpret the chemical changes occurring on low carbon steel during atmospheric and accelerated corrosion conditions with the objective of finding a correlation between its accelerated and long-term corrosion performance. The current results of correlating data from marine atmospheric exposure conditions at the Kennedy Space Center beachside corrosion test site, alternating seawater spray, and immersion in typical electrochemical laboratory conditions, will be presented. Key words: atmospheric exposure, accelerated corrosion testing, alternating seawater spray, marine, correlation, seawater, carbon steel, long-term corrosion performance prediction, X-ray photoelectron spectroscopy.

  10. Qualitative assessment of ultra-fast non-Grotthuss proton dynamics in S1 excited state of liquid H2O from ab initio time-dependent density functional theory★

    NASA Astrophysics Data System (ADS)

    Ziaei, Vafa; Bredow, Thomas

    2017-11-01

    We study qualitatively ultra-fast proton transfer (PT) in the first singlet (S1) state of liquid water (absorption onset) through excited-state dynamics by means of time-dependent density functional theory and ab initio Born-Oppenheimer molecular dynamics. We find that after the initial excitation, a PT occurs in S1 in form of a rapid jump to a neighboring water molecule, on which the proton either may rest for a relatively long period of time (as a consequence of possible defect in the hydrogen bond network) followed by back and forth hops to its neighboring water molecule or from which it further moves to the next water molecule accompanied by back and forth movements. In this way, the proton may become delocalized over a long water wire branch, followed again by back and forth jumps or short localization on a water molecule for some femtoseconds. As a result, the mechanism of PT in S1 is in most cases highly non-Grotthuss-like, delayed and discrete. Furthermore, upon PT an excess charge is ejected to the solvent trap, the so-called solvated electron. The spatial extent of the ejected solvated electron is mainly localized within one solvent shell with overlappings on the nearest neighbor water molecules and delocalizing (diffuse) tails extending beyond the first solvent sphere. During the entire ultra-short excited-state dynamics the remaining OH radical from the initially excited water molecule exhibits an extremely low mobility and is non-reactive. Supplementary material in the form of one pdf file available from the Journal web page at http://https://doi.org/10.1140/epjb/e2017-80329-7.

  11. Nitrogen and phosphorus limitation over long-term ecosystem development in terrestrial ecosystems.

    PubMed

    Menge, Duncan N L; Hedin, Lars O; Pacala, Stephen W

    2012-01-01

    Nutrient limitation to net primary production (NPP) displays a diversity of patterns as ecosystems develop over a range of timescales. For example, some ecosystems transition from N limitation on young soils to P limitation on geologically old soils, whereas others appear to remain N limited. Under what conditions should N limitation and P limitation prevail? When do transitions between N and P limitation occur? We analyzed transient dynamics of multiple timescales in an ecosystem model to investigate these questions. Post-disturbance dynamics in our model are controlled by a cascade of rates, from plant uptake (very fast) to litter turnover (fast) to plant mortality (intermediate) to plant-unavailable nutrient loss (slow) to weathering (very slow). Young ecosystems are N limited when symbiotic N fixation (SNF) is constrained and P weathering inputs are high relative to atmospheric N deposition and plant N:P demand, but P limited under opposite conditions. In the absence of SNF, N limitation is likely to worsen through succession (decades to centuries) because P is mineralized faster than N. Over long timescales (centuries and longer) this preferential P mineralization increases the N:P ratio of soil organic matter, leading to greater losses of plant-unavailable N versus P relative to plant N:P demand. These loss dynamics favor N limitation on older soils despite the rising organic matter N:P ratio. However, weathering depletion favors P limitation on older soils when continual P inputs (e.g., dust deposition) are low, so nutrient limitation at the terminal equilibrium depends on the balance of these input and loss effects. If NPP switches from N to P limitation over long time periods, the transition time depends most strongly on the P weathering rate. At all timescales SNF has the capacity to overcome N limitation, so nutrient limitation depends critically on limits to SNF.

  12. A mixing timescale model for TPDF simulations of turbulent premixed flames

    DOE PAGES

    Kuron, Michael; Ren, Zhuyin; Hawkes, Evatt R.; ...

    2017-02-06

    Transported probability density function (TPDF) methods are an attractive modeling approach for turbulent flames as chemical reactions appear in closed form. However, molecular micro-mixing needs to be modeled and this modeling is considered a primary challenge for TPDF methods. In the present study, a new algebraic mixing rate model for TPDF simulations of turbulent premixed flames is proposed, which is a key ingredient in commonly used molecular mixing models. The new model aims to properly account for the transition in reactive scalar mixing rate behavior from the limit of turbulence-dominated mixing to molecular mixing behavior in flamelets. An a priorimore » assessment of the new model is performed using direct numerical simulation (DNS) data of a lean premixed hydrogen–air jet flame. The new model accurately captures the mixing timescale behavior in the DNS and is found to be a significant improvement over the commonly used constant mechanical-to-scalar mixing timescale ratio model. An a posteriori TPDF study is then performed using the same DNS data as a numerical test bed. The DNS provides the initial conditions and time-varying input quantities, including the mean velocity, turbulent diffusion coefficient, and modeled scalar mixing rate for the TPDF simulations, thus allowing an exclusive focus on the mixing model. Here, the new mixing timescale model is compared with the constant mechanical-to-scalar mixing timescale ratio coupled with the Euclidean Minimum Spanning Tree (EMST) mixing model, as well as a laminar flamelet closure. It is found that the laminar flamelet closure is unable to properly capture the mixing behavior in the thin reaction zones regime while the constant mechanical-to-scalar mixing timescale model under-predicts the flame speed. Furthermore, the EMST model coupled with the new mixing timescale model provides the best prediction of the flame structure and flame propagation among the models tested, as the dynamics of reactive

  13. A mixing timescale model for TPDF simulations of turbulent premixed flames

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kuron, Michael; Ren, Zhuyin; Hawkes, Evatt R.

    Transported probability density function (TPDF) methods are an attractive modeling approach for turbulent flames as chemical reactions appear in closed form. However, molecular micro-mixing needs to be modeled and this modeling is considered a primary challenge for TPDF methods. In the present study, a new algebraic mixing rate model for TPDF simulations of turbulent premixed flames is proposed, which is a key ingredient in commonly used molecular mixing models. The new model aims to properly account for the transition in reactive scalar mixing rate behavior from the limit of turbulence-dominated mixing to molecular mixing behavior in flamelets. An a priorimore » assessment of the new model is performed using direct numerical simulation (DNS) data of a lean premixed hydrogen–air jet flame. The new model accurately captures the mixing timescale behavior in the DNS and is found to be a significant improvement over the commonly used constant mechanical-to-scalar mixing timescale ratio model. An a posteriori TPDF study is then performed using the same DNS data as a numerical test bed. The DNS provides the initial conditions and time-varying input quantities, including the mean velocity, turbulent diffusion coefficient, and modeled scalar mixing rate for the TPDF simulations, thus allowing an exclusive focus on the mixing model. Here, the new mixing timescale model is compared with the constant mechanical-to-scalar mixing timescale ratio coupled with the Euclidean Minimum Spanning Tree (EMST) mixing model, as well as a laminar flamelet closure. It is found that the laminar flamelet closure is unable to properly capture the mixing behavior in the thin reaction zones regime while the constant mechanical-to-scalar mixing timescale model under-predicts the flame speed. Furthermore, the EMST model coupled with the new mixing timescale model provides the best prediction of the flame structure and flame propagation among the models tested, as the dynamics of reactive

  14. The neural processing of hierarchical structure in music and speech at different timescales

    PubMed Central

    Farbood, Morwaread M.; Heeger, David J.; Marcus, Gary; Hasson, Uri; Lerner, Yulia

    2015-01-01

    Music, like speech, is a complex auditory signal that contains structures at multiple timescales, and as such is a potentially powerful entry point into the question of how the brain integrates complex streams of information. Using an experimental design modeled after previous studies that used scrambled versions of a spoken story (Lerner et al., 2011) and a silent movie (Hasson et al., 2008), we investigate whether listeners perceive hierarchical structure in music beyond short (~6 s) time windows and whether there is cortical overlap between music and language processing at multiple timescales. Experienced pianists were presented with an extended musical excerpt scrambled at multiple timescales—by measure, phrase, and section—while measuring brain activity with functional magnetic resonance imaging (fMRI). The reliability of evoked activity, as quantified by inter-subject correlation of the fMRI responses, was measured. We found that response reliability depended systematically on musical structure coherence, revealing a topographically organized hierarchy of processing timescales. Early auditory areas (at the bottom of the hierarchy) responded reliably in all conditions. For brain areas at the top of the hierarchy, the original (unscrambled) excerpt evoked more reliable responses than any of the scrambled excerpts, indicating that these brain areas process long-timescale musical structures, on the order of minutes. The topography of processing timescales was analogous with that reported previously for speech, but the timescale gradients for music and speech overlapped with one another only partially, suggesting that temporally analogous structures—words/measures, sentences/musical phrases, paragraph/sections—are processed separately. PMID:26029037

  15. Long-Term Dynamics of Autonomous Fractional Differential Equations

    NASA Astrophysics Data System (ADS)

    Liu, Tao; Xu, Wei; Xu, Yong; Han, Qun

    This paper aims to investigate long-term dynamic behaviors of autonomous fractional differential equations with effective numerical method. The long-term dynamic behaviors predict where systems are heading after long-term evolution. We make some modification and transplant cell mapping methods to autonomous fractional differential equations. The mapping time duration of cell mapping is enlarged to deal with the long memory effect. Three illustrative examples, i.e. fractional Lotka-Volterra equation, fractional van der Pol oscillator and fractional Duffing equation, are studied with our revised generalized cell mapping method. We obtain long-term dynamics, such as attractors, basins of attraction, and saddles. Compared with some existing stability and numerical results, the validity of our method is verified. Furthermore, we find that the fractional order has its effect on the long-term dynamics of autonomous fractional differential equations.

  16. Analysis of timescale to consensus in voting dynamics with more than two options

    NASA Astrophysics Data System (ADS)

    Wu, Degang; Szeto, Kwok Yip

    2018-04-01

    We generalize a binary majority-vote model on adaptive networks to its plurality-vote counterpart and analyze the timescale to consensus when voters are given more than two options. When opinions are uniformly distributed in the population of voters in the initial state, we find that the timescale to consensus is shorter than the binary vote model from both numerical simulations and mathematical analysis using the master equation for the three-state plurality-vote model. When intervention such as opinion conversion is allowed, as in the case of sudden change of mind of voter for any reason, the effort needed to push the fragmented three-opinion population in the thermodynamic limit to the consensus state, measured in minimal intervention cost, is less than that needed to push a polarized two-opinion population to the consensus state, when the degree (p ) of homophily is less than 0.8. For a finite system, the fragmented three-opinion population will spontaneously reach the consensus state, with faster time to consensus, compared to polarized two-opinion population, for a broad range of p .

  17. Ultra-Large Solar Sail

    NASA Technical Reports Server (NTRS)

    Burton, Rodney; Coverstone, Victoria

    2009-01-01

    UltraSail is a next-generation ultra-large (km2 class) sail system. Analysis of the launch, deployment, stabilization, and control of these sails shows that high-payload-mass fractions for interplanetary and deep-space missions are possible. UltraSail combines propulsion and control systems developed for formation-flying microsatellites with a solar sail architecture to achieve controllable sail areas approaching 1 km2. Electrically conductive CP-1 polyimide film results in sail subsystem area densities as low as 5 g/m2. UltraSail produces thrust levels many times those of ion thrusters used for comparable deep-space missions. The primary innovation involves the near-elimination of sail-supporting structures by attaching each blade tip to a formation- flying microsatellite, which deploys the sail and then articulates the sail to provide attitude control, including spin stabilization and precession of the spin axis. These microsatellite tips are controlled by microthrusters for sail-film deployment and mission operations. UltraSail also avoids the problems inherent in folded sail film, namely stressing, yielding, or perforating, by storing the film in a roll for launch and deployment. A 5-km long by 2 micrometer thick film roll on a mandrel with a 1 m circumference (32 cm diameter) has a stored thickness of 5 cm. A 5 m-long mandrel can store a film area of 25,000 m2, and a four-blade system has an area of 0.1 sq km.

  18. Stellar differential rotation and coronal time-scales

    NASA Astrophysics Data System (ADS)

    Gibb, G. P. S.; Jardine, M. M.; Mackay, D. H.

    2014-10-01

    We investigate the time-scales of evolution of stellar coronae in response to surface differential rotation and diffusion. To quantify this, we study both the formation time and lifetime of a magnetic flux rope in a decaying bipolar active region. We apply a magnetic flux transport model to prescribe the evolution of the stellar photospheric field, and use this to drive the evolution of the coronal magnetic field via a magnetofrictional technique. Increasing the differential rotation (i.e. decreasing the equator-pole lap time) decreases the flux rope formation time. We find that the formation time is dependent upon the lap time and the surface diffusion time-scale through the relation τ_Form ∝ √{τ_Lapτ_Diff}. In contrast, the lifetimes of flux ropes are proportional to the lap time (τLife∝τLap). With this, flux ropes on stars with a differential rotation of more than eight times the solar value have a lifetime of less than 2 d. As a consequence, we propose that features such as solar-like quiescent prominences may not be easily observable on such stars, as the lifetimes of the flux ropes which host the cool plasma are very short. We conclude that such high differential rotation stars may have very dynamical coronae.

  19. The origin of Total Solar Irradiance variability on timescales less than a day

    NASA Astrophysics Data System (ADS)

    Shapiro, Alexander; Krivova, Natalie; Schmutz, Werner; Solanki, Sami K.; Leng Yeo, Kok; Cameron, Robert; Beeck, Benjamin

    2016-07-01

    Total Solar Irradiance (TSI) varies on timescales from minutes to decades. It is generally accepted that variability on timescales of a day and longer is dominated by solar surface magnetic fields. For shorter time scales, several additional sources of variability have been proposed, including convection and oscillation. However, available simplified and highly parameterised models could not accurately explain the observed variability in high-cadence TSI records. We employed the high-cadence solar imagery from the Helioseismic and Magnetic Imager onboard the Solar Dynamics Observatory and the SATIRE (Spectral And Total Irradiance Reconstruction) model of solar irradiance variability to recreate the magnetic component of TSI variability. The recent 3D simulations of solar near-surface convection with MURAM code have been used to calculate the TSI variability caused by convection. This allowed us to determine the threshold timescale between TSI variability caused by the magnetic field and convection. Our model successfully replicates the TSI measurements by the PICARD/PREMOS radiometer which span the period of July 2010 to February 2014 at 2-minute cadence. Hence, we demonstrate that solar magnetism and convection can account for TSI variability at all timescale it has ever been measured (sans the 5-minute component from p-modes).

  20. Characterizing hyporheic exchange processes using high-frequency electrical conductivity-discharge relationships on subhourly to interannual timescales

    NASA Astrophysics Data System (ADS)

    Singley, Joel G.; Wlostowski, Adam N.; Bergstrom, Anna J.; Sokol, Eric R.; Torrens, Christa L.; Jaros, Chris; Wilson, Colleen E.; Hendrickson, Patrick J.; Gooseff, Michael N.

    2017-05-01

    Concentration-discharge (C-Q) relationships are often used to quantify source water contributions and biogeochemical processes occurring within catchments, especially during discrete hydrological events. Yet, the interpretation of C-Q hysteresis is often confounded by complexity of the critical zone, such as numerous source waters and hydrochemical nonstationarity. Consequently, researchers must often ignore important runoff pathways and geochemical sources/sinks, especially the hyporheic zone because it lacks a distinct hydrochemical signature. Such simplifications limit efforts to identify processes responsible for the transience of C-Q hysteresis over time. To address these limitations, we leverage the hydrologic simplicity and long-term, high-frequency Q and electrical conductivity (EC) data from streams in the McMurdo Dry Valleys, Antarctica. In this two end-member system, EC can serve as a proxy for the concentration of solutes derived from the hyporheic zone. We utilize a novel approach to decompose loops into subhysteretic EC-Q dynamics to identify individual mechanisms governing hysteresis across a wide range of timescales. We find that hydrologic and hydraulic processes govern EC response to diel and seasonal Q variability and that the effects of hyporheic mixing processes on C-Q transience differ in short and long streams. We also observe that variable hyporheic turnover rates govern EC-Q patterns at daily to interannual timescales. Last, subhysteretic analysis reveals a period of interannual freshening of glacial meltwater streams related to the effects of unsteady flow on hyporheic exchange. The subhysteretic analysis framework we introduce may be applied more broadly to constrain the processes controlling C-Q transience and advance understanding of catchment evolution.

  1. Ultra-wide bandpass filter based on long-period fiber gratings and the evanescent field coupling between two fibers.

    PubMed

    Kim, Myoung Jin; Jung, Yong Min; Kim, Bok Hyeon; Han, Won-Taek; Lee, Byeong Ha

    2007-08-20

    We demonstrate a fiber-based bandpass filter with an ultra-wide spectral bandwidth. The ultra-wide band feature is achieved by inscribing a long-period fiber grating (LPG) in a specially-designed low index core single mode fiber. To get the bandpass function, the evanescent field coupling between two attached fibers is utilized. By applying strain, the spectral shape of the pass-band is adjusted to flat-top and Gaussian shapes. For the flat-top case, the bandwidth is obtained ~ 160 nm with an insertion loss of ~ 2 dB. With strain, the spectral shape is switched into a Gaussian one, which has ~ 120 nm FWHM and ~ 4.18 dB insertion loss at the peak.

  2. Reduction of furnace temperature in ultra long carbon nanotube growth by plasmonic excitation of electron Fermi gas of catalytic nanocluster

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Saeidi, Mohammadreza, E-mail: Saeidi.mr@gmail.com, E-mail: m.saeidi@shahed.ac.ir

    2016-06-15

    In this paper, a novel physical method is presented to reduce the temperature of the furnace and prevent loss of thermal energy in ultra long carbon nanotube (CNT) growth process by catalytic chemical vapor deposition. This method is based on the plasmonic excitation of electron Fermi gas of catalytic nanocluster sitting at tip end of CNT by ultraviolet (UV) irradiation. Physical concepts of the method are explained in detail. The results of applying the presented method consequences to an appropriate tip-growth mechanism of the ultra long CNTs show that, in the presence of plasmonic excitation, the growth rate of themore » CNT is enhanced. Demonstration of temperature reduction and simultaneous increase in CNT length by UV irradiation with the proper frequency are the most important and practical result of the paper. All results are interpreted and discussed.« less

  3. Recent studies on nanosecond-timescale pressurized gas discharges

    DOE PAGES

    Yatom, S.; Shlapakovski, A.; Beilin, L.; ...

    2016-10-05

    The results of recent experimental and numerical studies of nanosecond high-voltage discharges in pressurized gases are reviewed. The discharges were ignited in a diode filled by different gases within a wide range of pressures by an applied pulsed voltage or by a laser pulse in the gas-filled charged resonant microwave cavity. Fast-framing imaging of light emission, optical emission spectroscopy, X-ray foil spectrometry and coherent anti-Stokes Raman scattering were used to study temporal and spatial evolution of the discharge plasma density and temperature, energy distribution function of runaway electrons and dynamics of the electric field in the plasma channel. The resultsmore » obtained allow a deeper understanding of discharge dynamical properties in the nanosecond timescale, which is important for various applications of these types of discharges in pressurized gases.« less

  4. Ultra-long acting calcium channel blockers may decrease accuracy of the acetylcholine provocation test.

    PubMed

    Kurabayashi, Manabu; Asano, Mitsutoshi; Shimura, Tsukasa; Suzuki, Hidetoshi; Aoyagi, Hideshi; Yamauchi, Yasuteru; Okishige, Kaoru; Ashikaga, Takashi; Isobe, Mitsuaki

    2017-06-01

    When drug-induced coronary spasm provocation tests are performed, a washout period of >48h for calcium channel blockers (CCBs) is uniformly recommended. However, each CCB has a distinct half-life, and little is known about the influence of prior oral administration of CCBs on acetylcholine provocation test to evaluate coronary vasomotor reaction. We examined 245 consecutive patients with suspected vasospastic angina who had undergone acetylcholine provocation test. Of those patients, 29 patients had been on amlodipine, an ultra-long term acting CCB (group A), 34 on other CCBs (group O), and 182 patients on no CCB (group N). After CCBs had been withheld > 48h, we performed acetylcholine provocation, which resulted in 152 positive, 36 intermediate, and 57 negative reactions. We evaluated coronary artery tone calculated as follows: (luminal diameter after nitrate-baseline luminal diameter)÷(luminal diameter after nitrate)×100 (%). In group A patients, coronary artery tone was lower (A:9.1±6.9% vs. O:11.7±8.3% vs. N:12.1±8.5%, p=0.0011) and the positive rate of acetylcholine provocation test was lower than group O and group N (A:41% vs. O:68% vs. N:64%, p=0.047). Multivariate logistic analysis showed that taking amlodipine until 2days before acetylcholine provocation test was a significant inverse predictor for acetylcholine-provoked coronary spasm (odds ratio 0.327; 95% confidence interval 0.125-0.858, p=0.023). Residual vasodilatory effects of ultra-long acting CCB may decrease coronary artery tone and the vasoconstrictive reaction to acetylcholine suggesting that a 2-day pre-test drug holiday may not be long enough. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. North-South precipitation patterns in western North America on interannual-to-decadal timescales

    USGS Publications Warehouse

    Dettinger, M.D.; Cayan, D.R.; Diaz, Henry F.; Meko, D.M.

    1998-01-01

    The overall amount of precipitation deposited along the West Coast and western cordillera of North America from 25??to 55??N varies from year to year, and superimposed on this domain-average variability are varying north-south contrasts on timescales from at least interannual to interdecadal. In order to better understand the north-south precipitation contrasts, their interannual and decadal variations are studied in terms of how much they affect overall precipitation amounts and how they are related to large-scale climatic patterns. Spatial empirical orthogonal functions (EOFs) and spatial moments (domain average, central latitude, and latitudinal spread) of zonally averaged precipitation anomalies along the westernmost parts of North America are analyzed, and each is correlated with global sea level pressure (SLP) and sea surface temperature series, on interannual (defined here as 3-7 yr) and decadal (>7 yr) timescales. The interannual band considered here corresponds to timescales that are particularly strong in tropical climate variations and thus is expected to contain much precipitation variability that is related to El Nino-Southern Oscillation; the decadal scale is defined so as to capture the whole range of long-term climatic variations affecting western North America. Zonal EOFs of the interannual and decadal filtered versions of the zonal-precipitation series are remarkably similar. At both timescales, two leading EOFs describe 1) a north-south seesaw of precipitation pivoting near 40??N and 2) variations in precipitation near 40??N, respectively. The amount of overall precipitation variability is only about 10% of the mean and is largely determined by precipitation variations around 40??-45??N and most consistently influenced by nearby circulation patterns; in this sense, domain-average precipitation is closely related to the second EOF. The central latitude and latitudinal spread of precipitation distributions are strongly influenced by precipitation

  6. Residue selective 15N CEST and CPMG experiments for studies of millisecond timescale protein dynamics.

    PubMed

    Niu, Xiaogang; Ding, Jienv; Zhang, Wenbo; Li, Qianwen; Hu, Yunfei; Jin, Changwen

    2018-06-01

    Proteins are intrinsically dynamic molecules and undergo exchanges among multiple conformations to perform biological functions. The CPMG relaxation dispersion and CEST experiments are two important solution NMR techniques for characterizing the conformational exchange processes on the millisecond timescale. Traditional pseudo 3D 15 N CEST and CPMG experiments have certain limitations in their applications. For example, both experiments have low sensitivity for broadened resonances, and the process of optimizing sample conditions and experimental parameters are often time consuming. To overcome these limitations, we herein present a new set of residue selective 15 N CEST and CPMG pulse sequences by employing the Hartmann-Hahn cross-polarization transfer of magnetization in both 1D and 2D schemes. Combined with frequency labeling in the indirect dimension using only a small number of increments, the pulse sequences in the 2D scheme can be applied on resonances in overlapped regions of the 1 H- 15 N HSQC spectrum. The pulse sequences were further applied on several proteins, demonstrating their advantages over the traditional CEST and CPMG experiments under specific circumstances. Copyright © 2018 Elsevier Inc. All rights reserved.

  7. The Analytical Limits of Modeling Short Diffusion Timescales

    NASA Astrophysics Data System (ADS)

    Bradshaw, R. W.; Kent, A. J.

    2016-12-01

    Chemical and isotopic zoning in minerals is widely used to constrain the timescales of magmatic processes such as magma mixing and crystal residence, etc. via diffusion modeling. Forward modeling of diffusion relies on fitting diffusion profiles to measured compositional gradients. However, an individual measurement is essentially an average composition for a segment of the gradient defined by the spatial resolution of the analysis. Thus there is the potential for the analytical spatial resolution to limit the timescales that can be determined for an element of given diffusivity, particularly where the scale of the gradient approaches that of the measurement. Here we use a probabilistic modeling approach to investigate the effect of analytical spatial resolution on estimated timescales from diffusion modeling. Our method investigates how accurately the age of a synthetic diffusion profile can be obtained by modeling an "unknown" profile derived from discrete sampling of the synthetic compositional gradient at a given spatial resolution. We also include the effects of analytical uncertainty and the position of measurements relative to the diffusion gradient. We apply this method to the spatial resolutions of common microanalytical techniques (LA-ICP-MS, SIMS, EMP, NanoSIMS). Our results confirm that for a given diffusivity, higher spatial resolution gives access to shorter timescales, and that each analytical spacing has a minimum timescale, below which it overestimates the timescale. For example, for Ba diffusion in plagioclase at 750 °C timescales are accurate (within 20%) above 10, 100, 2,600, and 71,000 years at 0.3, 1, 5, and 25 mm spatial resolution, respectively. For Sr diffusion in plagioclase at 750 °C, timescales are accurate above 0.02, 0.2, 4, and 120 years at the same spatial resolutions. Our results highlight the importance of selecting appropriate analytical techniques to estimate accurate diffusion-based timescales.

  8. Trefoil knot timescales for reconnection and helicity

    NASA Astrophysics Data System (ADS)

    Kerr, Robert M.

    2018-02-01

    Three-dimensional images of evolving numerical trefoil vortex knots are used to study the growth and decay of the enstrophy and helicity. Negative helicity density (h< 0) plays several roles. First, during anti-parallel reconnection, sheets of oppositely signed helicity dissipation of equal magnitude on either side of the maximum of the enstrophy dissipation allow the global helicity { H } to be preserved through the first reconnection, as suggested theoretically (Laing et al 2015 Sci. Rep. 5 9224) and observed experimentally (Scheeler et al 2014a Proc. Natl Acad. Sci. 111 15350-5). Next, to maintain the growth of the enstrophy and positive helicity within the trefoil while { H } is preserved, h< 0 forms in the outer parts of the trefoil so long as the periodic boundaries do not interfere. To prevent that, the domain size {\\ell } is increased as the viscosity ν \\to 0. Combined, this allows two sets of trefoils to form a new scaling regime with linearly decreasing {(\\sqrt{ν }Z(t))}-1/2 up to common ν-independent times t x that the graphics show is when the first reconnection ends. During this phase there is good correspondence between the evolution of the simulated vortices and the reconnecting experimental trefoil of Kleckner and Irvine (2017 Nat. Phys. 9 253-8) when time is scaled by their respective nonlinear timescales t f . The timescales t f are based upon by the radii r f of the trefoils and their circulations Γ, so long as the strong camber of the experimental hydrofoil models is used to correct the published experimental circulations Γ that use only the flat-plate approximation.

  9. Ultra-long-duration local anesthesia produced by injection of lecithin-coated methoxyflurane microdroplets.

    PubMed

    Haynes, D H; Kirkpatrick, A F

    1985-11-01

    This study was designed to evaluate a new drug delivery system. The authors undertook to determine if microdroplets prepared by encapsulating volatile anesthetics with a membrane of lecithin could be used for local anesthesia. Local anesthesia was determined by monitoring the response of the rat to tail clamping and electrical stimulation of the skin following the intradermal injection of the microdroplets. Microdroplets were prepared from isoflurane, enflurane, halothane, methoxyflurane, diethyl ether, chloroform, and heptane. Although all microdroplet preparations produced local anesthesia, only methoxyflurane microdroplets produced an ultra-long duration of local anesthesia (approximately 24 h). Further characterization of the methoxyflurane microdroplets revealed two important differences from conventional local anesthetics. First, the local anesthetic effect of methoxyflurane reached a plateau that did not change significantly for 20 h while the injection of lidocaine and bupivacaine resulted in a peak effect that returned to baseline within 1 and 3 h, respectively. Second, the anesthetic effect of methoxyflurane remained essentially localized to the site of injection, while the anesthetic effect of lidocaine and bupivacaine migrated 15 cm in less than 1 h. The toxicity and safety of methoxyflurane were evaluated. When administered over the dosage range 1-16% (v/v) intradermally, or by injections into muscle, or by repeat injections every 4 days for 16 days, all animals regained their pretreatment response to painful stimulations, and there was no evidence of gross injury to tissue. Deliberate intravenous injection of 0.8 ml of 6.7% (v/v) methoxyflurane microdroplets had no apparent anesthetic or toxic effect. The present study demonstrates that methoxyflurane microdroplets produce an anesthetic effect that is highly localized, stable in intensity, ultra-long in duration, and reversible.

  10. OWL representation of the geologic timescale implementing stratigraphic best practice

    NASA Astrophysics Data System (ADS)

    Cox, S. J.

    2011-12-01

    The geologic timescale is a cornerstone of the earth sciences. Versions are available from many sources, with the following being of particular interest: (i) The official International Stratigraphic Chart (ISC) is maintained by the International Commission for Stratigraphy (ICS), following principles developed over the last 40 years. ICS provides the data underlying the chart as part of a specialized software package, and the chart itself as a PDF using the standard colours; (ii) ITC Enschede has developed a representation of the timescale as a thesaurus in SKOS, used in a Web Map Service delivery system; (iii) JPL's SWEET ontology includes a geologic timescale. This takes full advantage of the capabilities of OWL. However, each of these has limitations - The ISC falls down because of incompatibility with web technologies; - While SKOS supports multilingual labelling, SKOS does not adequately support timescale semantics, in particular since it does not include ordering relationships; - The SWEET version (as of version 2) is not fully aligned to the model used by ICS, in particular not recognizing the role of the Global Boundary Stratotype Sections and Point (GSSP). Furthermore, it is distributed as static documents, rather than through a dynamic API using SPARQL. The representation presented in this paper overcomes all of these limitations as follows: - the timescale model is formulated as an OWL ontology - the ontology is directly derived from the UML representation of the ICS best practice proposed by Cox & Richard [2005], and subsequently included as the Geologic Timescale package in GeoSciML (http://www.geosciml.org); this includes links to GSSPs as per the ICS process - key properties in the ontology are also asserted to be subProperties of SKOS properties (topConcept and broader/narrower relations) in order to support SKOS-based queries; SKOS labelling is used to support multi-lingual naming and synonyms - the International Stratigraphic Chart is implemented

  11. Trace gas variability within the Asian monsoon anticyclone on intraseasonal and interannual timescales

    NASA Astrophysics Data System (ADS)

    Nützel, Matthias; Dameris, Martin; Fierli, Federico; Stiller, Gabriele; Garny, Hella; Jöckel, Patrick

    2016-04-01

    The Asian monsoon and the associated monsoon anticyclone have the potential of substantially influencing the composition of the UTLS (upper troposphere/lower stratosphere) and hence global climate. Here we study the variability of the Asian summer monsoon anticyclone in the UTLS on intraseasonal and interannual timescales using results from long term simulations performed with the CCM EMAC (ECHAM5/MESSy Atmospheric Chemistry). In particular, we focus on specified dynamics simulations (Newtonian relaxation to ERA-Interim data) covering the period 1980-2013, which have been performed within the ESCiMo (Earth System Chemistry integrated Modelling) project (Jöckel et al., GMDD, 2015). Our main focus lies on variability of the anticyclone's strength (in terms of potential vorticity, geopotential and circulation) and variability in trace gas signatures (O3, H2O) within the anticyclone. To support our findings, we also include observations from satellites (MIPAS, MLS). Our work is linked to the EU StratoClim campaign in 2016.

  12. Angular-momentum couplings in ultra-long-range giant dipole molecules

    NASA Astrophysics Data System (ADS)

    Stielow, Thomas; Scheel, Stefan; Kurz, Markus

    2018-02-01

    In this article we extend the theory of ultra-long-range giant dipole molecules, formed by an atom in a giant dipole state and a ground-state alkali-metal atom, by angular-momentum couplings known from recent works on Rydberg molecules. In addition to s -wave scattering, the next higher order of p -wave scattering in the Fermi pseudopotential describing the binding mechanism is considered. Furthermore, the singlet and triplet channels of the scattering interaction as well as angular-momentum couplings such as hyperfine interaction and Zeeman interactions are included. Within the framework of Born-Oppenheimer theory, potential energy surfaces are calculated in both first-order perturbation theory and exact diagonalization. Besides the known pure triplet states, mixed-spin character states are obtained, opening up a whole new landscape of molecular potentials. We determine exact binding energies and wave functions of the nuclear rotational and vibrational motion numerically from the various potential energy surfaces.

  13. Catch and Release of Cytokines Mediated by Tumor Phosphatidylserine Converts Transient Exposure into Long-Lived Inflammation.

    PubMed

    Oyler-Yaniv, Jennifer; Oyler-Yaniv, Alon; Shakiba, Mojdeh; Min, Nina K; Chen, Ying-Han; Cheng, Sheue-Yann; Krichevsky, Oleg; Altan-Bonnet, Nihal; Altan-Bonnet, Grégoire

    2017-06-01

    Immune cells constantly survey the host for pathogens or tumors and secrete cytokines to alert surrounding cells of these threats. In vivo, activated immune cells secrete cytokines for several hours, yet an acute immune reaction occurs over days. Given these divergent timescales, we addressed how cytokine-responsive cells translate brief cytokine exposure into phenotypic changes that persist over long timescales. We studied melanoma cell responses to transient exposure to the cytokine interferon γ (IFNγ) by combining a systems-scale analysis of gene expression dynamics with computational modeling and experiments. We discovered that IFNγ is captured by phosphatidylserine (PS) on the surface of viable cells both in vitro and in vivo then slowly released to drive long-term transcription of cytokine-response genes. This mechanism introduces an additional function for PS in dynamically regulating inflammation across diverse cancer and primary cell types and has potential to usher in new immunotherapies targeting PS and inflammatory pathways. Published by Elsevier Inc.

  14. Chandrasekhar's dynamical friction and non-extensive statistics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Silva, J.M.; Lima, J.A.S.; De Souza, R.E.

    2016-05-01

    The motion of a point like object of mass M passing through the background potential of massive collisionless particles ( m || M ) suffers a steady deceleration named dynamical friction. In his classical work, Chandrasekhar assumed a Maxwellian velocity distribution in the halo and neglected the self gravity of the wake induced by the gravitational focusing of the mass M . In this paper, by relaxing the validity of the Maxwellian distribution due to the presence of long range forces, we derive an analytical formula for the dynamical friction in the context of the q -nonextensive kinetic theory. Inmore » the extensive limiting case ( q = 1), the classical Gaussian Chandrasekhar result is recovered. As an application, the dynamical friction timescale for Globular Clusters spiraling to the galactic center is explicitly obtained. Our results suggest that the problem concerning the large timescale as derived by numerical N -body simulations or semi-analytical models can be understood as a departure from the standard extensive Maxwellian regime as measured by the Tsallis nonextensive q -parameter.« less

  15. Dynamic Sensorimotor Planning during Long-Term Sequence Learning: The Role of Variability, Response Chunking and Planning Errors

    PubMed Central

    Verstynen, Timothy; Phillips, Jeff; Braun, Emily; Workman, Brett; Schunn, Christian; Schneider, Walter

    2012-01-01

    Many everyday skills are learned by binding otherwise independent actions into a unified sequence of responses across days or weeks of practice. Here we looked at how the dynamics of action planning and response binding change across such long timescales. Subjects (N = 23) were trained on a bimanual version of the serial reaction time task (32-item sequence) for two weeks (10 days total). Response times and accuracy both showed improvement with time, but appeared to be learned at different rates. Changes in response speed across training were associated with dynamic changes in response time variability, with faster learners expanding their variability during the early training days and then contracting response variability late in training. Using a novel measure of response chunking, we found that individual responses became temporally correlated across trials and asymptoted to set sizes of approximately 7 bound responses at the end of the first week of training. Finally, we used a state-space model of the response planning process to look at how predictive (i.e., response anticipation) and error-corrective (i.e., post-error slowing) processes correlated with learning rates for speed, accuracy and chunking. This analysis yielded non-monotonic association patterns between the state-space model parameters and learning rates, suggesting that different parts of the response planning process are relevant at different stages of long-term learning. These findings highlight the dynamic modulation of response speed, variability, accuracy and chunking as multiple movements become bound together into a larger set of responses during sequence learning. PMID:23056630

  16. Reliability of ultra-thin insulation coatings for long-term electrophysiological recordings

    NASA Astrophysics Data System (ADS)

    Hooker, S. A.

    2006-03-01

    Improved measurement of neural signals is needed for research into Alzheimer's, Parkinson's, epilepsy, strokes, and spinal cord injuries. At the heart of such instruments are microelectrodes that measure electrical signals in the body. Such electrodes must be small, stable, biocompatible, and robust. However, it is also important that they be easily implanted without causing substantial damage to surrounding tissue. Tissue damage can lead to the generation of immune responses that can interfere with the electrical measurement, preventing long-term recording. Recent advances in microfabrication and nanotechnology afford the opportunity to dramatically reduce the physical dimensions of recording electrodes, thereby minimizing insertion damage. However, one potential cause for concern is the reliability of the insulating coatings, applied to these ultra-fine-diameter wires to precisely control impedance. Such coatings are often polymeric and are applied everywhere but the sharpened tips of the wires, resulting in nominal impedances between 0.5 MOhms and 2.0 MOhms. However, during operation, the polymer degrades, changing the exposed area and the impedance. In this work, ultra-thin ceramic coatings were deposited as an alternative to polymer coatings. Processing conditions were varied to determine the effect of microstructure on measurement stability during two-electrode measurements in a standard buffer solution. Coatings were applied to seven different metals to determine any differences in performance due to the surface characteristics of the underlying wire. Sintering temperature and wire type had significant effects on coating degradation. Dielectric breakdown was also observed at relatively low voltages, indicating that test conditions must be carefully controlled to maximize reliability.

  17. Bed load transport over a broad range of timescales: Determination of three regimes of fluctuations

    NASA Astrophysics Data System (ADS)

    Ma, Hongbo; Heyman, Joris; Fu, Xudong; Mettra, Francois; Ancey, Christophe; Parker, Gary

    2014-12-01

    This paper describes the relationship between the statistics of bed load transport flux and the timescale over which it is sampled. A stochastic formulation is developed for the probability distribution function of bed load transport flux, based on the Ancey et al. (2008) theory. An analytical solution for the variance of bed load transport flux over differing sampling timescales is presented. The solution demonstrates that the timescale dependence of the variance of bed load transport flux reduces to a three-regime relation demarcated by an intermittency timescale (tI) and a memory timescale (tc). As the sampling timescale increases, this variance passes through an intermittent stage (≪tI), an invariant stage (tI < t < tc), and a memoryless stage (≫ tc). We propose a dimensionless number (Ra) to represent the relative strength of fluctuation, which provides a common ground for comparison of fluctuation strength among different experiments, as well as different sampling timescales for each experiment. Our analysis indicates that correlated motion and the discrete nature of bed load particles are responsible for this three-regime behavior. We use the data from three experiments with high temporal resolution of bed load transport flux to validate the proposed three-regime behavior. The theoretical solution for the variance agrees well with all three sets of experimental data. Our findings contribute to the understanding of the observed fluctuations of bed load transport flux over monosize/multiple-size grain beds, to the characterization of an inherent connection between short-term measurements and long-term statistics, and to the design of appropriate sampling strategies for bed load transport flux.

  18. Ancient DNA from marine mammals: studying long-lived species over ecological and evolutionary timescales.

    PubMed

    Foote, Andrew D; Hofreiter, Michael; Morin, Phillip A

    2012-01-20

    Marine mammals have long generation times and broad, difficult to sample distributions, which makes inferring evolutionary and demographic changes using field studies of extant populations challenging. However, molecular analyses from sub-fossil or historical materials of marine mammals such as bone, tooth, baleen, skin, fur, whiskers and scrimshaw using ancient DNA (aDNA) approaches provide an opportunity for investigating such changes over evolutionary and ecological timescales. Here, we review the application of aDNA techniques to the study of marine mammals. Most of the studies have focused on detecting changes in genetic diversity following periods of exploitation and environmental change. To date, these studies have shown that even small sample sizes can provide useful information on historical genetic diversity. Ancient DNA has also been used in investigations of changes in distribution and range of marine mammal species; we review these studies and discuss the limitations of such 'presence only' studies. Combining aDNA data with stable isotopes can provide further insights into changes in ecology and we review past studies and suggest future potential applications. We also discuss studies reconstructing inter- and intra-specific phylogenies from aDNA sequences and discuss how aDNA sequences could be used to estimate mutation rates. Finally, we highlight some of the problems of aDNA studies on marine mammals, such as obtaining sufficient sample sizes and calibrating for the marine reservoir effect when radiocarbon-dating such wide-ranging species. Copyright © 2011 Elsevier GmbH. All rights reserved.

  19. Timescales and Mechanisms of Sigh-Like Bursting and Spiking in Models of Rhythmic Respiratory Neurons.

    PubMed

    Wang, Yangyang; Rubin, Jonathan E

    2017-12-01

    Neural networks generate a variety of rhythmic activity patterns, often involving different timescales. One example arises in the respiratory network in the pre-Bötzinger complex of the mammalian brainstem, which can generate the eupneic rhythm associated with normal respiration as well as recurrent low-frequency, large-amplitude bursts associated with sighing. Two competing hypotheses have been proposed to explain sigh generation: the recruitment of a neuronal population distinct from the eupneic rhythm-generating subpopulation or the reconfiguration of activity within a single population. Here, we consider two recent computational models, one of which represents each of the hypotheses. We use methods of dynamical systems theory, such as fast-slow decomposition, averaging, and bifurcation analysis, to understand the multiple-timescale mechanisms underlying sigh generation in each model. In the course of our analysis, we discover that a third timescale is required to generate sighs in both models. Furthermore, we identify the similarities of the underlying mechanisms in the two models and the aspects in which they differ.

  20. Experimental evidence of the self-similarity and long-range correlations of the edge fluctuations in HT-6M tokamak

    NASA Astrophysics Data System (ADS)

    Wang, Wen-hao; Yu, Chang-xuan; Wen, Yi-zhi; Xu, Yu-hong; Ling, Bi-li; Gong, Xian-zu; Liu, Bao-hua; Wan, Bao-nian

    2001-02-01

    For a better understanding of long timescale transport dynamics, the rescaled range analysis techniques, the autocorrelation function (ACF) and the probability distribution function (PDF) are used to investigate long-range dependences in edge plasma fluctuations in an HT-6M tokamak. The results reveal the self-similar characters of the electrostatic fluctuations with self-similarity parameters (Hurst exponent) ranging from 0.64 to 0.79, taking into consideration the Er×B rotation-sheared effect. Fluctuation ACFs of both the ion saturation current and the floating potential, as well as PDF of the turbulence-induced particle flux, have two distinct timescales. One corresponds to the decorrelation timescale of local fluctuations (µs) and the other lasts to the order of the confinement time (ms). All these experimental results suggest that some of the mechanisms of the underlying turbulence are consistent with plasma transport as characterized by self-organized criticality (SOC).

  1. Long-term employment among people at ultra-high risk for psychosis.

    PubMed

    Cotter, Jack; Lin, Ashleigh; Drake, Richard J; Thompson, Andrew; Nelson, Barnaby; McGorry, Patrick; Wood, Stephen J; Yung, Alison R

    2017-06-01

    Psychotic disorders are associated with high rates of sustained unemployment, however, little is known about the long-term employment outcome of people at ultra-high risk (UHR) of developing psychosis. We sought to investigate the long-term unemployment rate and baseline predictors of employment status at follow-up in a large UHR cohort. 268 UHR patients recruited from the Personal Assessment and Crisis Evaluation clinic in Melbourne, Australia were followed-up over 2-14years after initial presentation to the service. Individuals in no form of employment or education were classed as unemployed. Logistic regression analyses were used to examine predictors of employment outcome. A high rate of unemployment was present at follow-up in this UHR sample (23%). At baseline, those who were unemployed at follow-up had a longer duration of untreated illness, more severe negative symptoms, lower IQ, poorer social and occupational functioning and reported more childhood trauma than the employed group. At follow-up, unemployed individuals exhibited significantly more severe symptoms on all measures and were more likely to have been diagnosed with a mood, anxiety, psychotic or substance use disorder. Childhood trauma and the duration of untreated illness at baseline were significant independent predictors of employment status at follow-up in the multivariate analyses. Nearly a quarter of this UHR sample was unemployed at long-term follow-up. The duration of untreated illness and the effects of childhood trauma are potentially modifiable risk factors for long-term employment outcome in this group. Vocational support may be beneficial for many UHR patients presenting to services. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. Long-range correlations and fractal dynamics in C. elegans: Changes with aging and stress

    NASA Astrophysics Data System (ADS)

    Alves, Luiz G. A.; Winter, Peter B.; Ferreira, Leonardo N.; Brielmann, Renée M.; Morimoto, Richard I.; Amaral, Luís A. N.

    2017-08-01

    Reduced motor control is one of the most frequent features associated with aging and disease. Nonlinear and fractal analyses have proved to be useful in investigating human physiological alterations with age and disease. Similar findings have not been established for any of the model organisms typically studied by biologists, though. If the physiology of a simpler model organism displays the same characteristics, this fact would open a new research window on the control mechanisms that organisms use to regulate physiological processes during aging and stress. Here, we use a recently introduced animal-tracking technology to simultaneously follow tens of Caenorhabdits elegans for several hours and use tools from fractal physiology to quantitatively evaluate the effects of aging and temperature stress on nematode motility. Similar to human physiological signals, scaling analysis reveals long-range correlations in numerous motility variables, fractal properties in behavioral shifts, and fluctuation dynamics over a wide range of timescales. These properties change as a result of a superposition of age and stress-related adaptive mechanisms that regulate motility.

  3. Least-rattling feedback from strong time-scale separation

    NASA Astrophysics Data System (ADS)

    Chvykov, Pavel; England, Jeremy

    2018-03-01

    In most interacting many-body systems associated with some "emergent phenomena," we can identify subgroups of degrees of freedom that relax on dramatically different time scales. Time-scale separation of this kind is particularly helpful in nonequilibrium systems where only the fast variables are subjected to external driving; in such a case, it may be shown through elimination of fast variables that the slow coordinates effectively experience a thermal bath of spatially varying temperature. In this paper, we investigate how such a temperature landscape arises according to how the slow variables affect the character of the driven quasisteady state reached by the fast variables. Brownian motion in the presence of spatial temperature gradients is known to lead to the accumulation of probability density in low-temperature regions. Here, we focus on the implications of attraction to low effective temperature for the long-term evolution of slow variables. After quantitatively deriving the temperature landscape for a general class of overdamped systems using a path-integral technique, we then illustrate in a simple dynamical system how the attraction to low effective temperature has a fine-tuning effect on the slow variable, selecting configurations that bring about exceptionally low force fluctuation in the fast-variable steady state. We furthermore demonstrate that a particularly strong effect of this kind can take place when the slow variable is tuned to bring about orderly, integrable motion in the fast dynamics that avoids thermalizing energy absorbed from the drive. We thus point to a potentially general feedback mechanism in multi-time-scale active systems, that leads to the exploration of slow variable space, as if in search of fine tuning for a "least-rattling" response in the fast coordinates.

  4. Synthesis and properties of ultra-long InP nanowires on glass.

    PubMed

    Dhaka, Veer; Pale, Ville; Khayrudinov, Vladislav; Kakko, Joona-Pekko; Haggren, Tuomas; Jiang, Hua; Kauppinen, Esko; Lipsanen, Harri

    2016-12-16

    We report on the synthesis of Au-catalyzed InP nanowires (NWs) on low-cost glass substrates. Ultra-dense and ultra-long (up to ∼250 μm) InP NWs, with an exceptionally high growth rate of ∼25 μm min -1 , were grown directly on glass using metal organic vapor phase epitaxy (MOVPE). Structural properties of InP NWs grown on glass were similar to the ones grown typically on Si substrates showing many structural twin faults but the NWs on glass always exhibited a stronger photoluminescence (PL) intensity at room temperature. The PL measurements of NWs grown on glass reveal two additional prominent impurity related emission peaks at low temperature (10 K). In particular, the strongest unusual emission peak with an activation energy of 23.8 ± 2 meV was observed at 928 nm. Different possibilities including the role of native defects (phosphorus and/or indium vacancies) are discussed but most likely the origin of this PL peak is related to the impurity incorporation from the glass substrate. Furthermore, despite the presence of suspected impurities, the NWs on glass show outstanding light absorption in a wide spectral range (60%-95% for λ = 300-1600 nm). The optical properties and the NW growth mechanism on glass is discussed qualitatively. We attribute the exceptionally high growth rate mostly to the atmospheric pressure growth conditions of our MOVPE reactor and stronger PL intensity on glass due to the impurity doping. Overall, the III-V NWs grown on glass are similar to the ones grown on semiconductor substrates but offer additional advantages such as low-cost and light transparency.

  5. The timescales of global surface-ocean connectivity.

    PubMed

    Jönsson, Bror F; Watson, James R

    2016-04-19

    Planktonic communities are shaped through a balance of local evolutionary adaptation and ecological succession driven in large part by migration. The timescales over which these processes operate are still largely unresolved. Here we use Lagrangian particle tracking and network theory to quantify the timescale over which surface currents connect different regions of the global ocean. We find that the fastest path between two patches--each randomly located anywhere in the surface ocean--is, on average, less than a decade. These results suggest that marine planktonic communities may keep pace with climate change--increasing temperatures, ocean acidification and changes in stratification over decadal timescales--through the advection of resilient types.

  6. The Exoplant Migration Timescale from K2 Young Clusters

    NASA Astrophysics Data System (ADS)

    Rizzuto, Aaron C.; Mann, Andrew; Kraus, Adam L.; Ireland, Michael

    2017-01-01

    Planetary Migration models for close-in exoplanets(a < 0.1 AU, P < 20 days) can be loosely divided into three categories: Disk-driven migration, binary-star planet interaction, and planet-planet interaction. Disk migration, occurs over the lifetime of the protoplanetary disk (<5 Myr), while migration involving dynamical multi-body interactions operate on timescales of ~100’s of Myr to ~1Gyr, a lengthier process than disk migration. It is unclear which of these is the dominating mechanism.The K2 mission has measured planet formation timescales and migration pathways by sampling groups of stars at key pre-main-sequence ages: Over the past 10 campaigns, multiple groups of young stars have been observed by K2, ranging from the 10 Myr Upper Scorpius OB association, through the ˜120 Myr Pleiades, the ˜600-800 Myr Hyades and Praesepe moving groups, to the original Kepler Field. The frequency, orbital and compositional properties of the exoplanet population in these samples of different age, with careful treatment of detection completeness, will be sufficient to address the question of exoplanet migration as their host stars are settling onto the main sequence.We will present the initial results of a program to directly address the question of planet migration with a uniform injection-recovery tests on a new K2 detrending pipeline that is optimized for the particular case of young, rotationally variable stars in K2 to robustly measure the detectability of planets of differing size and orbit. Initial results point towards a migration timescale of 200-700 Myr, which is consistent with the slower planet-planet scattering or Kozai migration models.

  7. Ultra-rapid EOP determination with VLBI

    NASA Astrophysics Data System (ADS)

    Haas, Rüdiger; Kurihara, Shinobu; Nozawa, Kentaro; Hobiger, Thomas; Lovell, Jim; McCallum, Jamie; Quick, Jonathan

    2013-04-01

    In 2007 the Geospatial information Authority of Japan (GSI) and the Onsala Space Observatory (OSO) started a project aiming at determining the earth rotation angle, usually expressed as dUT1, in near real-time. In the beginning of this project dedicated one hour long one-baseline experiments were observed periodically using the VLBI stations Onsala (Sweden) and Tsukuba (Japan). The strategy is that the observed VLBI-data are sent in real-time via the international optical fibre backbone to the VLBI-correlator at Tsukuba where the data are correlated and analyzed in near-real time, producing ultra-rapid dUT1 results. An offline version of this strategy has been adopted in 2009 for the regular VLBI intensive series INT-2 involving Wettzell (Germany) and Tsukuba. Since March 2010 the INT-2 is using real-time e-transfer, too, and since June 2010 also automated analysis. Starting in 2009 the ultra-rapid approach was applied to regular 24 hour long VLBI-sessions that involve Tsukuba and Onsala, so that ultra-rapid dUT1 results can be produced already during ongoing VLBI-sessions. This strategy was successfully operated during the 15 days long CONT11 campaign. In 2011 the ultra-rapid strategy was extended to involve a network of VLBI-stations, so that not only dUT1 but also the polar motion components can be determined in near real-time. Initially, in November 2011 a dedicated three-station session was observed involving Onsala, Tsukuba and Hobart (Tasmania, Australia). In 2012 several regular 24 hour long IVS-sessions that involved Onsala, Tsukuba and HartRAO (South Africa) were operated with the ultra-rapid strategy, and in several cases also Hobart was added as a fourth station. For this project we use the new analysis software c5++ developed by the National Institute of Information and Communications Technology (NICT). In this presentation we give an overview of the UREOP-project, describe the recent developments, and discuss the obtained results.

  8. The contribution of local and transport processes to phytoplankton biomass variability over different timescales in the Upper James River, Virginia

    NASA Astrophysics Data System (ADS)

    Qin, Qubin; Shen, Jian

    2017-09-01

    Although both local processes (photosynthesis, respiration, grazing, and settling), and transport processes (advective transport and diffusive transport) significantly affect local phytoplankton dynamics, it is difficult to separate their contributions and to investigate the relative importance of each process to the local variability of phytoplankton biomass over different timescales. A method of using the transport rate is introduced to quantify the contribution of transport processes. By combining the time-varying transport rate and high-frequency observed chlorophyll a data, we can explicitly examine the impact of local and transport processes on phytoplankton biomass over a range of timescales from hourly to annually. For the Upper James River, results show that the relative importance of local and transport processes differs on different timescales. Local processes dominate phytoplankton variability on daily to weekly timescales, whereas the contribution of transport processes increases on seasonal to annual timescales and reaches equilibrium with local processes. With the use of the transport rate and high-frequency chlorophyll a data, a method similar to the open water oxygen method for metabolism is also presented to estimate phytoplankton primary production.

  9. Evolution of Timescales from Astronomy to Physical Metrology

    DTIC Science & Technology

    2011-07-20

    2000 [7] recommended the use of the ‘non-rotating origin’ both in the Geocentric Celestial Reference System (GCRS) and the International Terrestrial...timescale defined in a geocentric reference frame with the SI second as realized on the rotating geoid as the scale unit’ [30, 31]. This meant that it was...of the new timescale for apparent geocentric ephemerides, will be 1977 January 1d.0003725 (1d 00h 00m 32.184s) exactly. (b) The unit of this timescale

  10. Entanglement timescale

    NASA Astrophysics Data System (ADS)

    Yang, I.-Sheng

    2018-03-01

    We derive the time scale for two initially pure subsystems to become entangled with each other through an arbitrary Hamiltonian that couples them. The entanglement timescale is inversely proportional to the "correlated uncertainty" between the two subsystems, a quantity which we will define and analyze in this paper. Our result is still applicable when one of the subsystems started in an arbitrarily mixed state, thus it generalizes the well-known "decoherence time scale" while coupled to a thermal state.

  11. IONIZATION EQUILIBRIUM TIMESCALES IN COLLISIONAL PLASMAS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, Randall K.; Hughes, John P., E-mail: rsmith@cfa.harvard.ed, E-mail: jph@physics.rutgers.ed

    2010-07-20

    Astrophysical shocks or bursts from a photoionizing source can disturb the typical collisional plasma found in galactic interstellar media or the intergalactic medium. The spectrum emitted by this plasma contains diagnostics that have been used to determine the time since the disturbing event, although this determination becomes uncertain as the elements in the plasma return to ionization equilibrium. A general solution for the equilibrium timescale for each element arises from the elegant eigenvector method of solution to the problem of a non-equilibrium plasma described by Masai and Hughes and Helfand. In general, the ionization evolution of an element Z inmore » a constant electron temperature plasma is given by a coupled set of Z + 1 first-order differential equations. However, they can be recast as Z uncoupled first-order differential equations using an eigenvector basis for the system. The solution is then Z separate exponential functions, with the time constants given by the eigenvalues of the rate matrix. The smallest of these eigenvalues gives the scale of the slowest return to equilibrium independent of the initial conditions, while conversely the largest eigenvalue is the scale of the fastest change in the ion population. These results hold for an ionizing plasma, a recombining plasma, or even a plasma with random initial conditions, and will allow users of these diagnostics to determine directly if their best-fit result significantly limits the timescale since a disturbance or is so close to equilibrium as to include an arbitrarily long time.« less

  12. A flexible, robust and antifouling asymmetric membrane based on ultra-long ceramic/polymeric fibers for high-efficiency separation of oil/water emulsions.

    PubMed

    Wang, Kui; Yiming, Wubulikasimu; Saththasivam, Jayaprakash; Liu, Zhaoyang

    2017-07-06

    Polymeric and ceramic asymmetric membranes have dominated commercial membranes for water treatment. However, polymeric membranes are prone to becoming fouled, while ceramic membranes are mechanically fragile. Here, we report a novel concept to develop asymmetric membranes based on ultra-long ceramic/polymeric fibers, with the combined merits of good mechanical stability, excellent fouling resistance and high oil/water selectivity, in order to meet the stringent requirements for practical oil/water separation. The ultra-long dimensions of ceramic nanofibers/polymeric microfibers endow this novel membrane with mechanical flexibility and robustness, due to the integrated and intertwined structure. This membrane is capable of separating oil/water emulsions with high oil-separation efficiency (99.9%), thanks to its nanoporous selective layer made of ceramic nanofibers. Further, this membrane also displays superior antifouling properties due to its underwater superoleophobicity and ultra-low oil adhesion of the ceramic-based selective layer. This membrane exhibits high water permeation flux (6.8 × 10 4 L m -2 h -1 bar -1 ) at low operation pressures, which is attributed to its 3-dimensional (3D) interconnected fiber-based structure throughout the membrane. In addition, the facile fabrication process and inexpensive materials required for this membrane suggest its significant potential for industrial applications.

  13. Universal timescales in the rheology of spheroid cell aggregates

    NASA Astrophysics Data System (ADS)

    Yu, Miao; Mahtabfar, Aria; Beleen, Paul; Foty, Ramsey; Zahn, Jeffrey; Shreiber, David; Liu, Liping; Lin, Hao

    2017-11-01

    The rheological properties of tissue play important roles in key biological processes including embryogenesis, cancer metastasis, and wound healing. Spheroid cell aggregate is a particularly interesting model system for the study of these phenomena. In the long time, they behave like drops with a surface tension. In the short, viscoelasticity also needs to be considered. In this work, we discover two coupled and universal timescales for spheroid aggregates. A total of 12 aggregate types (total aggregate number n =290) derived from L and GBM (glioblastoma multiforme) cells are studied with microtensiometer to obtain their surface tension. They are also allowed to relax upon release of the compression forces. The two timescales are observed during the relaxation process; their values do not depend on compression time nor the degree of deformation, and are consistent among all 12 types. Following prior work (Yu et al., Phys. Rev. Lett., 115:128303; Liu et al., J. Mech. Phys. Solids, 98:309-329) we use a rigorous mathematical theory to interpret the results, which reveals intriguing properties of the aggregates on both tissue and cellular levels. The mechanics of multicellular organization reflects both complexity and regularity due to strong active regulation.

  14. [94 km Brillouin distributed optical fiber sensors based on ultra-long fiber ring laser pumping].

    PubMed

    Yuan, Cheng-Xu; Wang, Zi-Nan; Jia, Xin-Hong; Li, Jin; Yan, Xiao-Dong; Cui, An-Bin

    2014-05-01

    A novel optical amplification configuration based on ultra-long fiber laser with a ring cavity was proposed and applied to Brillouin optical time-domain analysis (BOTDA) sensing system, in order to extend the measurement distance significantly. The parameters used in the experiment were optimized, considering the main limitations of the setup, such as depletion, self-phase modulation (SPM) and pump-signal relative intensity noise (RIN) transfer. Through analyzing Brillouin gain spectrum, we demonstrated distributed sensing over 94 km of standard single-mode fiber with 3 meter spatial resolution and strain/temperature accuracy of 28 /1. 4 degree C.

  15. Metastability and avalanche dynamics in strongly correlated gases with long-range interactions

    NASA Astrophysics Data System (ADS)

    Hruby, Lorenz; Dogra, Nishant; Landini, Manuele; Donner, Tobias; Esslinger, Tilman

    2018-03-01

    We experimentally study the stability of a bosonic Mott insulator against the formation of a density wave induced by long-range interactions and characterize the intrinsic dynamics between these two states. The Mott insulator is created in a quantum degenerate gas of 87-Rubidium atoms, trapped in a 3D optical lattice. The gas is located inside and globally coupled to an optical cavity. This causes interactions of global range, mediated by photons dispersively scattered between a transverse lattice and the cavity. The scattering comes with an atomic density modulation, which is measured by the photon flux leaking from the cavity. We initialize the system in a Mott-insulating state and then rapidly increase the global coupling strength. We observe that the system falls into either of two distinct final states. One is characterized by a low photon flux, signaling a Mott insulator, and the other is characterized by a high photon flux, which we associate with a density wave. Ramping the global coupling slowly, we observe a hysteresis loop between the two states—a further signature of metastability. A comparison with a theoretical model confirms that the metastability originates in the competition between short- and global-range interactions. From the increasing photon flux monitored during the switching process, we find that several thousand atoms tunnel to a neighboring site on the timescale of the single-particle dynamics. We argue that a density modulation, initially forming in the compressible surface of the trapped gas, triggers an avalanche tunneling process in the Mott-insulating region.

  16. Microsecond time-scale kinetics of transient biochemical reactions

    PubMed Central

    Mitić, Sandra; Strampraad, Marc J. F.; de Vries, Simon

    2017-01-01

    To afford mechanistic studies in enzyme kinetics and protein folding in the microsecond time domain we have developed a continuous-flow microsecond time-scale mixing instrument with an unprecedented dead-time of 3.8 ± 0.3 μs. The instrument employs a micro-mixer with a mixing time of 2.7 μs integrated with a 30 mm long flow-cell of 109 μm optical path length constructed from two parallel sheets of silver foil; it produces ultraviolet-visible spectra that are linear in absorbance up to 3.5 with a spectral resolution of 0.4 nm. Each spectrum corresponds to a different reaction time determined by the distance from the mixer outlet, and by the fluid flow rate. The reaction progress is monitored in steps of 0.35 μs for a total duration of ~600 μs. As a proof of principle the instrument was used to study spontaneous protein refolding of pH-denatured cytochrome c. Three folding intermediates were determined: after a novel, extremely rapid initial phase with τ = 4.7 μs, presumably reflecting histidine re-binding to the iron, refolding proceeds with time constants of 83 μs and 345 μs to a coordinatively saturated low-spin iron form in quasi steady state. The time-resolution specifications of our spectrometer for the first time open up the general possibility for comparison of real data and molecular dynamics calculations of biomacromolecules on overlapping time scales. PMID:28973014

  17. Intracellular Pressure Dynamics in Blebbing Cells

    PubMed Central

    Strychalski, Wanda; Guy, Robert D.

    2016-01-01

    Blebs are pressure-driven protrusions that play an important role in cell migration, particularly in three-dimensional environments. A bleb is initiated when the cytoskeleton detaches from the cell membrane, resulting in the pressure-driven flow of cytosol toward the area of detachment and local expansion of the cell membrane. Recent experiments involving blebbing cells have led to conflicting hypotheses regarding the timescale of intracellular pressure propagation. The interpretation of one set of experiments supports a poroelastic model of the cytoplasm that leads to slow pressure equilibration when compared to the timescale of bleb expansion. A different study concludes that pressure equilibrates faster than the timescale of bleb expansion. To address this discrepancy, a dynamic computational model of the cell was developed that includes mechanics of and the interactions among the cytoplasm, the actin cortex, the cell membrane, and the cytoskeleton. The model results quantify the relationship among cytoplasmic rheology, pressure, and bleb expansion dynamics, and provide a more detailed picture of intracellular pressure dynamics. This study shows the elastic response of the cytoplasm relieves pressure and limits bleb size, and that both permeability and elasticity of the cytoplasm determine bleb expansion time. Our model with a poroelastic cytoplasm shows that pressure disturbances from bleb initiation propagate faster than the timescale of bleb expansion and that pressure equilibrates slower than the timescale of bleb expansion. The multiple timescales in intracellular pressure dynamics explain the apparent discrepancy in the interpretation of experimental results. PMID:26958893

  18. Partitioning controls on Amazon forest photosynthesis between environmental and biotic factors at hourly to interannual timescales

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wu, Jin; Guan, Kaiyu; Hayek, Matthew

    Gross ecosystem productivity (GEP) in tropical forests varies both with the environment and with biotic changes in photosynthetic infrastructure, but our understanding of the relative effects of these factors across timescales is limited. Here, we used a statistical model to partition the variability of seven years of eddy covariance-derived GEP in a central Amazon evergreen forest into two main causes: variation in environmental drivers (solar radiation, diffuse light fraction, and vapor pressure deficit) that interact with model parameters that govern photosynthesis and biotic variation in canopy photosynthetic light-use efficiency associated with changes in the parameters themselves. Our fitted model wasmore » able to explain most of the variability in GEP at hourly (R 2 = 0.77) to interannual (R 2 = 0.80) timescales. At hourly timescales, we found that 75% of observed GEP variability could be attributed to environmental variability. When aggregating GEP to the longer timescales (daily, monthly, and yearly), however, environmental variation explained progressively less GEP variability: At monthly timescales, it explained only 3%, much less than biotic variation in canopy photosynthetic light-use efficiency, which accounted for 63%. These results challenge modeling approaches that assume GEP is primarily controlled by the environment at both short and long timescales. Our approach distinguishing biotic from environmental variability can help to resolve debates about environmental limitations to tropical forest photosynthesis. For example, we found that biotically regulated canopy photosynthetic light-use efficiency (associated with leaf phenology) increased with sunlight during dry seasons (consistent with light but not water limitation of canopy development) but that realized GEP was nonetheless lower relative to its potential efficiency during dry than wet seasons (consistent with water limitation of photosynthesis in given assemblages of leaves). Lastly

  19. Partitioning controls on Amazon forest photosynthesis between environmental and biotic factors at hourly to interannual timescales

    DOE PAGES

    Wu, Jin; Guan, Kaiyu; Hayek, Matthew; ...

    2016-09-19

    Gross ecosystem productivity (GEP) in tropical forests varies both with the environment and with biotic changes in photosynthetic infrastructure, but our understanding of the relative effects of these factors across timescales is limited. Here, we used a statistical model to partition the variability of seven years of eddy covariance-derived GEP in a central Amazon evergreen forest into two main causes: variation in environmental drivers (solar radiation, diffuse light fraction, and vapor pressure deficit) that interact with model parameters that govern photosynthesis and biotic variation in canopy photosynthetic light-use efficiency associated with changes in the parameters themselves. Our fitted model wasmore » able to explain most of the variability in GEP at hourly (R 2 = 0.77) to interannual (R 2 = 0.80) timescales. At hourly timescales, we found that 75% of observed GEP variability could be attributed to environmental variability. When aggregating GEP to the longer timescales (daily, monthly, and yearly), however, environmental variation explained progressively less GEP variability: At monthly timescales, it explained only 3%, much less than biotic variation in canopy photosynthetic light-use efficiency, which accounted for 63%. These results challenge modeling approaches that assume GEP is primarily controlled by the environment at both short and long timescales. Our approach distinguishing biotic from environmental variability can help to resolve debates about environmental limitations to tropical forest photosynthesis. For example, we found that biotically regulated canopy photosynthetic light-use efficiency (associated with leaf phenology) increased with sunlight during dry seasons (consistent with light but not water limitation of canopy development) but that realized GEP was nonetheless lower relative to its potential efficiency during dry than wet seasons (consistent with water limitation of photosynthesis in given assemblages of leaves). Lastly

  20. Dynamic Interaction of Long Suspension Bridges with Running Trains

    NASA Astrophysics Data System (ADS)

    XIA, H.; XU, Y. L.; CHAN, T. H. T.

    2000-10-01

    This paper presents an investigation of dynamic interaction of long suspension bridges with running trains. A three-dimensional finite element model is used to represent a long suspension bridge. Each 4-axle vehicle in a train is modelled by a 27-degrees-of-freedom dynamic system. The dynamic interaction between the bridge and train is realized through the contact forces between the wheels and track. By applying a mode superposition technique to the bridge only and taking the measured track irregularities as known quantities, the number of degrees of freedom (d.o.f.) the bridge-train system is significantly reduced and the coupled equations of motion are efficiently solved. The proposed formulation and the associated computer program are then applied to a real long suspension bridge carrying a railway within the bridge deck. The dynamic response of the bridge-train system and the derail and offload factors related to the running safety of the train are computed. The results show that the formulation presented in this paper can well predict dynamic behaviors of both bridge and train with reasonable computation efforts. Dynamic interaction between the long suspension bridge and train is not significant.

  1. SPITZER OBSERVATIONS OF LONG-TERM INFRARED VARIABILITY AMONG YOUNG STELLAR OBJECTS IN CHAMAELEON I

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Flaherty, Kevin M.; Herbst, William; DeMarchi, Lindsay

    Infrared variability is common among young stellar objects, with surveys finding daily to weekly fluctuations of a few tenths of a magnitude. Space-based observations can produce highly sampled infrared light curves, but are often limited to total baselines of about 1 month due to the orientation of the spacecraft. Here we present observations of the Chameleon I cluster, whose low declination makes it observable by the Spitzer Space Telescope over a 200-day period. We observe 30 young stellar objects with a daily cadence to better sample variability on timescales of months. We find that such variability is common, occurring inmore » ∼80% of the detected cluster members. The change in [3.6]–[4.5] color over 200 days for many of the sources falls between that expected for extinction and fluctuations in disk emission. With our high cadence and long baseline we can derive power spectral density curves covering two orders of magnitude in frequency and find significant power at low frequencies, up to the boundaries of our 200-day survey. Such long timescales are difficult to explain with variations driven by the interaction between the disk and stellar magnetic field, which has a dynamical timescale of days to weeks. The most likely explanation is either structural or temperature fluctuations spread throughout the inner ∼0.5 au of the disk, suggesting that the intrinsic dust structure is highly dynamic.« less

  2. Timescales of Land Surface Evapotranspiration Response

    NASA Technical Reports Server (NTRS)

    Scott, Russell; Entekhabi, Dara; Koster, Randal; Suarez, Max

    1997-01-01

    Soil and vegetation exert strong control over the evapotranspiration rate, which couples the land surface water and energy balances. A method is presented to quantify the timescale of this surface control using daily general circulation model (GCM) simulation values of evapotranspiration and precipitation. By equating the time history of evaporation efficiency (ratio of actual to potential evapotranspiration) to the convolution of precipitation and a unit kernel (temporal weighting function), response functions are generated that can be used to characterize the timescales of evapotranspiration response for the land surface model (LSM) component of GCMS. The technique is applied to the output of two multiyear simulations of a GCM, one using a Surface-Vegetation-Atmosphere-Transfer (SVAT) scheme and the other a Bucket LSM. The derived response functions show that the Bucket LSM's response is significantly slower than that of the SVAT across the globe. The analysis also shows how the timescales of interception reservoir evaporation, bare soil evaporation, and vegetation transpiration differ within the SVAT LSM.

  3. Long-term surface temperature modeling of Pluto

    NASA Astrophysics Data System (ADS)

    Earle, Alissa M.; Binzel, Richard P.; Young, Leslie A.; Stern, S. A.; Ennico, K.; Grundy, W.; Olkin, C. B.; Weaver, H. A.; New Horizons Geology and Geophysics Imaging Team

    2017-05-01

    NASA's New Horizons' reconnaissance of the Pluto system has revealed at high resolution the striking albedo contrasts from polar to equatorial latitudes on Pluto, as well as the sharpness of boundaries for longitudinal variations. These contrasts suggest that Pluto must undergo dynamic evolution that drives the redistribution of volatiles. Using the New Horizons results as a template, we explore the surface temperature variations driven seasonally on Pluto considering multiple timescales. These timescales include the current orbit (248 years) as well as the timescales for obliquity precession (peak-to-peak amplitude of 23° over 3 million years) and regression of the orbital longitude of perihelion (3.7 million years). These orbital variations create epochs of ;Extreme Seasons; where one pole receives a short, relatively warm summer and long winter, while the other receives a much longer, but less intense summer and short winter. We use thermal modeling to build upon the long-term insolation history model described by Earle and Binzel (2015) and investigate how these seasons couple with Pluto's albedo contrasts to create temperature effects. From this study we find that a bright region at the equator, once established, can become a site for net deposition. We see the region informally known as Sputnik Planitia as an example of this, and find it will be able to perpetuate itself as an ;always available; cold trap, thus having the potential to survive on million year or substantially longer timescales. Meanwhile darker, low-albedo, regions near the equator will remain relative warm and generally not attract volatile deposition. We argue that the equatorial region is a ;preservation zone; for whatever albedo is seeded there. This offers insight as to why the equatorial band of Pluto displays the planet's greatest albedo contrasts.

  4. Stochastic simulation of enzyme-catalyzed reactions with disparate timescales.

    PubMed

    Barik, Debashis; Paul, Mark R; Baumann, William T; Cao, Yang; Tyson, John J

    2008-10-01

    Many physiological characteristics of living cells are regulated by protein interaction networks. Because the total numbers of these protein species can be small, molecular noise can have significant effects on the dynamical properties of a regulatory network. Computing these stochastic effects is made difficult by the large timescale separations typical of protein interactions (e.g., complex formation may occur in fractions of a second, whereas catalytic conversions may take minutes). Exact stochastic simulation may be very inefficient under these circumstances, and methods for speeding up the simulation without sacrificing accuracy have been widely studied. We show that the "total quasi-steady-state approximation" for enzyme-catalyzed reactions provides a useful framework for efficient and accurate stochastic simulations. The method is applied to three examples: a simple enzyme-catalyzed reaction where enzyme and substrate have comparable abundances, a Goldbeter-Koshland switch, where a kinase and phosphatase regulate the phosphorylation state of a common substrate, and coupled Goldbeter-Koshland switches that exhibit bistability. Simulations based on the total quasi-steady-state approximation accurately capture the steady-state probability distributions of all components of these reaction networks. In many respects, the approximation also faithfully reproduces time-dependent aspects of the fluctuations. The method is accurate even under conditions of poor timescale separation.

  5. Reconciling long-term cultural diversity and short-term collective social behavior.

    PubMed

    Valori, Luca; Picciolo, Francesco; Allansdottir, Agnes; Garlaschelli, Diego

    2012-01-24

    An outstanding open problem is whether collective social phenomena occurring over short timescales can systematically reduce cultural heterogeneity in the long run, and whether offline and online human interactions contribute differently to the process. Theoretical models suggest that short-term collective behavior and long-term cultural diversity are mutually excluding, since they require very different levels of social influence. The latter jointly depends on two factors: the topology of the underlying social network and the overlap between individuals in multidimensional cultural space. However, while the empirical properties of social networks are intensively studied, little is known about the large-scale organization of real societies in cultural space, so that random input specifications are necessarily used in models. Here we use a large dataset to perform a high-dimensional analysis of the scientific beliefs of thousands of Europeans. We find that interopinion correlations determine a nontrivial ultrametric hierarchy of individuals in cultural space. When empirical data are used as inputs in models, ultrametricity has strong and counterintuitive effects. On short timescales, it facilitates a symmetry-breaking phase transition triggering coordinated social behavior. On long timescales, it suppresses cultural convergence by restricting it within disjoint groups. Moreover, ultrametricity implies that these results are surprisingly robust to modifications of the dynamical rules considered. Thus the empirical distribution of individuals in cultural space appears to systematically optimize the coexistence of short-term collective behavior and long-term cultural diversity, which can be realized simultaneously for the same moderate level of mutual influence in a diverse range of online and offline settings.

  6. Dynamics of long ring Raman fiber laser

    NASA Astrophysics Data System (ADS)

    Sukhanov, Sergey V.; Melnikov, Leonid A.; Mazhirina, Yulia A.

    2016-04-01

    The numerical model for dynamics of long fiber ring Raman laser is proposed. The model is based on the transport equations and Courant-Isaacson-Rees numerical method. Different regimes of a long ring fiber Raman laser are investigated.

  7. Ultra-high dynamic range electro-optic sampling for detecting millimeter and sub-millimeter radiation

    PubMed Central

    Ibrahim, Akram; Férachou, Denis; Sharma, Gargi; Singh, Kanwarpal; Kirouac-Turmel, Marie; Ozaki, Tsuneyuki

    2016-01-01

    Time-domain spectroscopy using coherent millimeter and sub-millimeter radiation (also known as terahertz radiation) is rapidly expanding its application, owing greatly to the remarkable advances in generating and detecting such radiation. However, many current techniques for coherent terahertz detection have limited dynamic range, thus making it difficult to perform some basic experiments that need to directly compare strong and weak terahertz signals. Here, we propose and demonstrate a novel technique based on cross-polarized spectral-domain interferometry to achieve ultra-high dynamic range electro-optic sampling measurement of coherent millimeter and sub-millimeter radiation. In our scheme, we exploit the birefringence in a single-mode polarization maintaining fiber in order to measure the phase change induced by the electric field of terahertz radiation in the detection crystal. With our new technique, we have achieved a dynamic range of 7 × 106, which is 4 orders of magnitude higher than conventional electro-optic sampling techniques, while maintaining comparable signal-to-noise ratio. The present technique is foreseen to have great impact on experiments such as linear terahertz spectroscopy of optically thick materials (such as aqueous samples) and nonlinear terahertz spectroscopy, where the higher dynamic range is crucial for proper interpretation of experimentally obtained results. PMID:26976363

  8. Ultra-high dynamic range electro-optic sampling for detecting millimeter and sub-millimeter radiation.

    PubMed

    Ibrahim, Akram; Férachou, Denis; Sharma, Gargi; Singh, Kanwarpal; Kirouac-Turmel, Marie; Ozaki, Tsuneyuki

    2016-03-15

    Time-domain spectroscopy using coherent millimeter and sub-millimeter radiation (also known as terahertz radiation) is rapidly expanding its application, owing greatly to the remarkable advances in generating and detecting such radiation. However, many current techniques for coherent terahertz detection have limited dynamic range, thus making it difficult to perform some basic experiments that need to directly compare strong and weak terahertz signals. Here, we propose and demonstrate a novel technique based on cross-polarized spectral-domain interferometry to achieve ultra-high dynamic range electro-optic sampling measurement of coherent millimeter and sub-millimeter radiation. In our scheme, we exploit the birefringence in a single-mode polarization maintaining fiber in order to measure the phase change induced by the electric field of terahertz radiation in the detection crystal. With our new technique, we have achieved a dynamic range of 7 × 10(6), which is 4 orders of magnitude higher than conventional electro-optic sampling techniques, while maintaining comparable signal-to-noise ratio. The present technique is foreseen to have great impact on experiments such as linear terahertz spectroscopy of optically thick materials (such as aqueous samples) and nonlinear terahertz spectroscopy, where the higher dynamic range is crucial for proper interpretation of experimentally obtained results.

  9. Seamless Modeling for Research & Predictability of Severe Tropical Storms from Weather-to-Climate Timescales

    NASA Astrophysics Data System (ADS)

    Ramaswamy, V.; Chen, J. H.; Delworth, T. L.; Knutson, T. R.; Lin, S. J.; Murakami, H.; Vecchi, G. A.

    2017-12-01

    Damages from catastrophic tropical storms such as the 2017 destructive hurricanes compel an acceleration of scientific advancements to understand the genesis, underlying mechanisms, frequency, track, intensity, and landfall of these storms. The advances are crucial to provide improved early information for planners and responders. We discuss the development and utilization of a global modeling capability based on a novel atmospheric dynamical core ("Finite-Volume Cubed Sphere or FV3") which captures the realism of the recent tropical storms and is a part of the NOAA Next-Generation Global Prediction System. This capability is also part of an emerging seamless modeling system at NOAA/ Geophysical Fluid Dynamics Laboratory for simulating the frequency of storms on seasonal and longer timescales with high fidelity e.g., Atlantic hurricane frequency over the past decades. In addition, the same modeling system has also been employed to evaluate the nature of projected storms on the multi-decadal scales under the influence of anthropogenic factors such as greenhouse gases and aerosols. The seamless modeling system thus facilitates research into and the predictability of severe tropical storms across diverse timescales of practical interest to several societal sectors.

  10. Modeling pedogenesis at multimillennium timescales: achievements and challenges

    NASA Astrophysics Data System (ADS)

    Finke, Peter

    2013-04-01

    in soil properties such as soil texture and soil structure; (iii) Developing adequate calibration techniques; (iv) Maximizing computational efficiency. Reconstruction of initial and boundary conditions requires multidisciplinary inputs either derived from proxies or from combined vegetation and climate development models. So far, the combination of pedogenetic models and combined vegetation/climate models is rare. At pedogenetic timescales, soil characteristics that are usually considered constant become dynamic: texture, OC, bulk density, precipitated salts, minerals, etc. Interactions and feedbacks between these characteristics and associated hydrological properties need attention, e.g. via pedotransfer functions. The same can be stated for the development of soil structure and associated preferential flow, which is still a challenge. At multimillennium temporal extents, the combination of long model runtime and the fact that most calibration data represent the current stage of soil development requires a special approach. Model performance can be evaluated at various timescales using unconventional proxies. Finally, recognizing the fact that matter redistribution at the landscape scale is of paramount importance at multimillennium extent requires the formulation of computationally efficient 3D models. This will surely involve analysis of the tradeoff between process detail, model accuracy, required boundary inputs and model runtime.

  11. Extremes in East African hydroclimate and links to Indo-Pacific variability on interannual to decadal timescales

    NASA Astrophysics Data System (ADS)

    Ummenhofer, Caroline C.; Kulüke, Marco; Tierney, Jessica E.

    2018-04-01

    East African hydroclimate exhibits considerable variability across a range of timescales, with implications for its population that depends on the region's two rainy seasons. Recent work demonstrated that current state-of-the-art climate models consistently underestimate the long rains in boreal spring over the Horn of Africa while overestimating the short rains in autumn. This inability to represent the seasonal cycle makes it problematic for climate models to project changes in East African precipitation. Here we consider whether this bias also has implications for understanding interannual and decadal variability in the East African long and short rains. Using a consistent framework with an unforced multi-century global coupled climate model simulation, the role of Indo-Pacific variability for East African rainfall is compared across timescales and related to observations. The dominant driver of East African rainfall anomalies critically depends on the timescale under consideration: Interannual variations in East African hydroclimate coincide with significant sea surface temperature (SST) anomalies across the Indo-Pacific, including those associated with the El Niño-Southern Oscillation (ENSO) in the eastern Pacific, and are linked to changes in the Walker circulation, regional winds and vertical velocities over East Africa. Prolonged drought/pluvial periods in contrast exhibit anomalous SST predominantly in the Indian Ocean and Indo-Pacific warm pool (IPWP) region, while eastern Pacific anomalies are insignificant. We assessed dominant frequencies in Indo-Pacific SST and found the eastern equatorial Pacific dominated by higher-frequency variability in the ENSO band, while the tropical Indian Ocean and IPWP exhibit lower-frequency variability beyond 10 years. This is consistent with the different contribution to regional precipitation anomalies for the eastern Pacific versus Indian Ocean and IPWP on interannual and decadal timescales, respectively. In the model

  12. Future ultra-speed tube-flight

    NASA Astrophysics Data System (ADS)

    Salter, Robert M.

    1994-05-01

    Future long-link, ultra-speed, surface transport systems will require electromagnetically (EM) driven and restrained vehicles operating under reduced-atmosphere in very straight tubes. Such tube-flight trains will be safe, energy conservative, pollution-free, and in a protected environment. Hypersonic (and even hyperballistic) speeds are theoretically achievable. Ultimate system choices will represent tradeoffs between amoritized capital costs (ACC) and operating costs. For example, long coasting links might employ aerodynamic lift coupled with EM restraint and drag make-up. Optimized, combined EM lift, and thrust vectors could reduce energy costs but at increased ACC. (Repulsive levitation can produce lift-over-drag l/d ratios a decade greater than aerodynamic), Alternatively, vehicle-emanated, induced-mirror fields in a conducting (aluminum sheet) road bed could reduce ACC but at substantial energy costs. Ultra-speed tube flight will demand fast-acting, high-precision sensors and computerized magnetic shimming. This same control system can maintain a magnetic 'guide way' invariant in inertial space with inertial detectors imbedded in tube structures to sense and correct for earth tremors. Ultra-speed tube flight can complete with aircraft for transit time and can provide even greater passenger convenience by single-model connections with local subways and feeder lines. Although cargo transport generally will not need to be performed at ultra speeds, such speeds may well be desirable for high throughput to optimize channel costs. Thus, a large and expensive pipeline might be replaced with small EM-driven pallets at high speeds.

  13. Future ultra-speed tube-flight

    NASA Technical Reports Server (NTRS)

    Salter, Robert M.

    1994-01-01

    Future long-link, ultra-speed, surface transport systems will require electromagnetically (EM) driven and restrained vehicles operating under reduced-atmosphere in very straight tubes. Such tube-flight trains will be safe, energy conservative, pollution-free, and in a protected environment. Hypersonic (and even hyperballistic) speeds are theoretically achievable. Ultimate system choices will represent tradeoffs between amoritized capital costs (ACC) and operating costs. For example, long coasting links might employ aerodynamic lift coupled with EM restraint and drag make-up. Optimized, combined EM lift, and thrust vectors could reduce energy costs but at increased ACC. (Repulsive levitation can produce lift-over-drag l/d ratios a decade greater than aerodynamic), Alternatively, vehicle-emanated, induced-mirror fields in a conducting (aluminum sheet) road bed could reduce ACC but at substantial energy costs. Ultra-speed tube flight will demand fast-acting, high-precision sensors and computerized magnetic shimming. This same control system can maintain a magnetic 'guide way' invariant in inertial space with inertial detectors imbedded in tube structures to sense and correct for earth tremors. Ultra-speed tube flight can complete with aircraft for transit time and can provide even greater passenger convenience by single-model connections with local subways and feeder lines. Although cargo transport generally will not need to be performed at ultra speeds, such speeds may well be desirable for high throughput to optimize channel costs. Thus, a large and expensive pipeline might be replaced with small EM-driven pallets at high speeds.

  14. Effects of fire frequency on long-term development of an oak-hickory forest in Missouri, U.S.A.

    Treesearch

    Benjamin O. Knapp; Michael A. Hullinger; John M. Kabrick

    2017-01-01

    Repeated prescribed burning over long timescales has some predictable effects on forest structure and composition, but multi-decadal patterns of stand dynamics and successional change with different fire frequencies have rarely been described. We used longitudinal data from a prescribed burning study conducted over a 63-year period to quantify stand structure (stem...

  15. Ablation dynamics - from absorption to heat accumulation/ultra-fast laser matter interaction

    NASA Astrophysics Data System (ADS)

    Kramer, Thorsten; Remund, Stefan; Jäggi, Beat; Schmid, Marc; Neuenschwander, Beat

    2018-05-01

    Ultra-short laser radiation is used in manifold industrial applications today. Although state-of-the-art laser sources are providing an average power of 10-100 W with repetition rates of up to several megahertz, most applications do not benefit from it. On the one hand, the processing speed is limited to some hundred millimeters per second by the dynamics of mechanical axes or galvanometric scanners. On the other hand, high repetition rates require consideration of new physical effects such as heat accumulation and shielding that might reduce the process efficiency. For ablation processes, process efficiency can be expressed by the specific removal rate, ablated volume per time, and average power. The analysis of the specific removal rate for different laser parameters, like average power, repetition rate or pulse duration, and process parameters, like scanning speed or material, can be used to find the best operation point for microprocessing applications. Analytical models and molecular dynamics simulations based on the so-called two-temperature model reveal the causes for the appearance of limiting physical effects. The findings of models and simulations can be used to take advantage and optimize processing strategies.

  16. Degludec, a new ultra-long-acting basal insulin for the treatment of diabetes mellitus type 1 and 2: advances in clinical research.

    PubMed

    Muñoz Torres, Manuel

    2014-03-01

    Degludec is the most recent molecule of the ultra-long-acting basal insulin analogues approved for human use. It forms soluble multihexamers which after subcutaneous injection are converted into monomers, and are thus slowly and continuously absorbed into the bloodstream. This absorption mechanism confers degludec an ultra-long and stable action profile, with no concentration peaks. This paper discusses the most recent studies in patients with type 1 and 2 diabetes mellitus, which showed degludec to be non inferior in decreasing HbA1c, ensuring optimum glycemic control similar to that achieved with insulin glargine or detemir. Degludec also had an improved safety profile, as it was associated to a significantly lower rate of nocturnal hypoglycemia in both types of diabetes and to a potentially lower overall hypoglycemia rate in type 2 DM. Degludec also opens the possibility to use more flexible regimens. Copyright © 2013 SEEN. Published by Elsevier Espana. All rights reserved.

  17. Long-time predictions in nonlinear dynamics

    NASA Technical Reports Server (NTRS)

    Szebehely, V.

    1980-01-01

    It is known that nonintegrable dynamical systems do not allow precise predictions concerning their behavior for arbitrary long times. The available series solutions are not uniformly convergent according to Poincare's theorem and numerical integrations lose their meaningfulness after the elapse of arbitrary long times. Two approaches are the use of existing global integrals and statistical methods. This paper presents a generalized method along the first approach. As examples long-time predictions in the classical gravitational satellite and planetary problems are treated.

  18. Glassy dynamics in three-dimensional embryonic tissues

    PubMed Central

    Schötz, Eva-Maria; Lanio, Marcos; Talbot, Jared A.; Manning, M. Lisa

    2013-01-01

    Many biological tissues are viscoelastic, behaving as elastic solids on short timescales and fluids on long timescales. This collective mechanical behaviour enables and helps to guide pattern formation and tissue layering. Here, we investigate the mechanical properties of three-dimensional tissue explants from zebrafish embryos by analysing individual cell tracks and macroscopic mechanical response. We find that the cell dynamics inside the tissue exhibit features of supercooled fluids, including subdiffusive trajectories and signatures of caging behaviour. We develop a minimal, three-parameter mechanical model for these dynamics, which we calibrate using only information about cell tracks. This model generates predictions about the macroscopic bulk response of the tissue (with no fit parameters) that are verified experimentally, providing a strong validation of the model. The best-fit model parameters indicate that although the tissue is fluid-like, it is close to a glass transition, suggesting that small changes to single-cell parameters could generate a significant change in the viscoelastic properties of the tissue. These results provide a robust framework for quantifying and modelling mechanically driven pattern formation in tissues. PMID:24068179

  19. A study of the dynamics of the equatorial lower stratosphere by use of ultra-long-duration balloons, 2, Gravity waves

    NASA Astrophysics Data System (ADS)

    Hertzog, A.; Vial, F.

    2001-10-01

    This study is the companion paper of Vial et al. [this issue]. A campaign of ultra-long-duration, superpressure balloons in the equatorial lower stratosphere was held in September 1998. By conception these balloons evolve on isopycnic surfaces. Pressure and position were measured every 12 min, which enable to infer the characteristics of gravity waves with periods between 1 hour and 1 day in this region of the atmosphere. The intrinsic-frequency spectra of horizontal wind fluctuations exhibit a -2 slope, while the one associated with vertical-wind fluctuations is flat. Significant inhomogeneity of the wave activity is observed, and the variance of the shortest frequency waves is found to be linked to the position of the balloons with respect to the Intertropical Convergence Zone. On average, the total energy associated with gravity waves in the period range studied in this paper is found to be ˜ 7 J kg-1. Calculations of momentum flux have also been undertaken. It appears that there is an approximate equipartition of flux between eastward and westward propagating gravity waves and that the absolute value of the flux is 8-12 × 10-3 m2 s-2 at 20 km. A larger flux is also observed above convective regions. These values suggest that gravity waves may carry the largest part of the Eliassen-Palm flux required for the driving of the quasi-biennial oscillation.

  20. Solar University-National Lab Ultra-Effective Program | Photovoltaic

    Science.gov Websites

    Lab Ultra-Effective Program Solar University-National lab Ultra-effective Program (SUN UP) was created scientists arise out of long-standing collaborations. SUN UP was created to facilitate these interactions of a young man working in a laboratory setting with equipment. The goal of SUN UP is to increase the

  1. Dynamics of genetic and morphological variability within Neandertals.

    PubMed

    Hawks, John

    2012-01-01

    Paleogenomics may suggest changes to the way anthropologists have discussed the dynamics and morphological diversity among Neandertals. Genetic comparisons show that later Neandertals had relatively low autosomal genetic variation compared to recent humans. The known mitochondrial sample from Neandertals covers a broader geographic and temporal range, and shows greater diversity. This review addresses how genetic data compare to morphological and archaeological evidence about Neandertal variation and dynamics. Traditional views emphasized the morphological differences between western and eastern Neandertal populations, and between early and later Neandertals. Genomes broadly support these groupings, without resolving the outstanding question of the affinities of specimens from southwest Asia. However, the pattern of genetic variation appears to reject a long, in situ transformation of Neandertal groups over time, suggesting instead a more rapid process of regional dispersal and partial population replacement. Archaeological indicators sample dynamics on a much finer timescale than morphological or genetic evidence, and point to dispersal and turnover among Neandertals on a regional scale. In this way, genetic evidence may provide a bridge between the timescales relevant to morphological and archaeological comparisons. New ways of looking at the morphology of Neandertals may yield a better picture of their interactions and movements.

  2. Seed-mediated synthesis of ultra-long copper nanowires and their application as transparent conducting electrodes

    NASA Astrophysics Data System (ADS)

    Kim, Hyunhong; Choi, Seong-Hyeon; Kim, Mijung; Park, Jang-Ung; Bae, Joonwon; Park, Jongnam

    2017-11-01

    Owing to a recent push toward one-dimensional nanomaterials, in this study, we report a seed-mediated synthetic strategy for copper nanowires (Cu NWs) production involving thermal decomposition of metal-surfactant complexes in an organic medium. Ultra-long Cu NWs with a high aspect ratio and uniform diameter were obtained by separating nucleation and growth steps. The underlying mechanism for nanowire formation was investigated, in addition, properties of the obtained Cu NWs were also characterized using diverse analysis techniques. The performance of resulting Cu NWs as transparent electrodes was demonstrated for potential application. This article can provide information on both new synthetic pathway and potential use of Cu NWs.

  3. H+ and O+ dynamics during ultra-low frequency waves in the Earth's magnetotail plasma sheet

    NASA Astrophysics Data System (ADS)

    De Spiegeleer, Alexandre; Hamrin, Maria; Pitkänen, Timo; Volwerk, Martin; Mouikis, Christopher; Kistler, Lynn; Nilsson, Hans; Norqvist, Patrik; Andersson, Laila

    2017-04-01

    The concentration of ionospheric oxygen (O^+) in the magnetotail plasma sheet can be relatively elevated depending on, for instance, the geomagnetic activity as well as the solar cycle. The dynamics of the tail plasma sheet can be affected by the presence of O+ via for example the generation of instabilities such as the Kelvin-Helmholtz instability. However, the O+ is not always taken into account when studying the dynamics of the tail plasma sheet. We investigate proton (H^+) and O+ during ultra-low frequency waves (period > 5 min) in the mid-tail plasma sheet (beyond 10R_E) using Cluster data. We observe that the velocity of O+ can be significantly different from that of H^+. When occuring, this velocity difference always seems to be in the direction parallel to the magnetic field. The parallel velocity of the two species can be observed to be somewhat out of phase, meaning that while one species flows in the parallel direction, the other flows in the anti-parallel direction. Possible causes for such large discrepancies between the dynamics of O+ and H+ are discussed.

  4. Finite-size effects in the dynamics of few bosons in a ring potential

    NASA Astrophysics Data System (ADS)

    Eriksson, G.; Bengtsson, J.; Karabulut, E. Ö.; Kavoulakis, G. M.; Reimann, S. M.

    2018-02-01

    We study the temporal evolution of a small number N of ultra-cold bosonic atoms confined in a ring potential. Assuming that initially the system is in a solitary-wave solution of the corresponding mean-field problem, we identify significant differences in the time evolution of the density distribution of the atoms when it instead is evaluated with the many-body Schrödinger equation. Three characteristic timescales are derived: the first is the period of rotation of the wave around the ring, the second is associated with a ‘decay’ of the density variation, and the third is associated with periodic ‘collapses’ and ‘revivals’ of the density variations, with a factor of \\sqrt{N} separating each of them. The last two timescales tend to infinity in the appropriate limit of large N, in agreement with the mean-field approximation. These findings are based on the assumption of the initial state being a mean-field state. We confirm this behavior by comparison to the exact solutions for a few-body system stirred by an external potential. We find that the exact solutions of the driven system exhibit similar dynamical features.

  5. Long-term changes after brief dynamic psychotherapy: symptomatic versus dynamic assessments.

    PubMed

    Høglend, P; Sørlie, T; Sørbye, O; Heyerdahl, O; Amlo, S

    1992-08-01

    Dynamic change in psychotherapy, as measured by theory-related or mode-specific instruments, have been criticized for being too intercorrelated with symptomatic change measures. In this study, long-term changes after brief dynamic psychotherapy were studied in 45 moderately disturbed neurotic patients by a reliable outcome battery. The factor structure of all the change variables suggested that they tapped 2 distinct and stable sources of variance: dynamic and symptomatic change. The categories of overall dynamic change were different from categories of change on the Global Assessment Scale. A small systematic difference was found between the categories of overall dynamic change and the categories of target complaints change also, due to false solutions of dynamic conflicts.

  6. The dynamical structure of the MEO region: long-term stability, chaos, and transport

    NASA Astrophysics Data System (ADS)

    Daquin, Jérôme; Rosengren, Aaron J.; Alessi, Elisa Maria; Deleflie, Florent; Valsecchi, Giovanni B.; Rossi, Alessandro

    2016-04-01

    It has long been suspected that the Global Navigation Satellite Systems exist in a background of complex resonances and chaotic motion; yet, the precise dynamical character of these phenomena remains elusive. Recent studies have shown that the occurrence and nature of the resonances driving these dynamics depend chiefly on the frequencies of nodal and apsidal precession and the rate of regression of the Moon's nodes. Woven throughout the inclination and eccentricity phase space is an exceedingly complicated web-like structure of lunisolar secular resonances, which become particularly dense near the inclinations of the navigation satellite orbits. A clear picture of the physical significance of these resonances is of considerable practical interest for the design of disposal strategies for the four constellations. Here we present analytical and semi-analytical models that accurately reflect the true nature of the resonant interactions, and trace the topological organization of the manifolds on which the chaotic motions take place. We present an atlas of FLI stability maps, showing the extent of the chaotic regions of the phase space, computed through a hierarchy of more realistic, and more complicated, models, and compare the chaotic zones in these charts with the analytical estimation of the width of the chaotic layers from the heuristic Chirikov resonance-overlap criterion. As the semi-major axis of the satellite is receding, we observe a transition from stable Nekhoroshev-like structures at three Earth radii, where regular orbits dominate, to a Chirikov regime where resonances overlap at five Earth radii. From a numerical estimation of the Lyapunov times, we find that many of the inclined, nearly circular orbits of the navigation satellites are strongly chaotic and that their dynamics are unpredictable on decadal timescales.

  7. Motions and entropies in proteins as seen in NMR relaxation experiments and molecular dynamics simulations.

    PubMed

    Allnér, Olof; Foloppe, Nicolas; Nilsson, Lennart

    2015-01-22

    Molecular dynamics simulations of E. coli glutaredoxin1 in water have been performed to relate the dynamical parameters and entropy obtained in NMR relaxation experiments, with results extracted from simulated trajectory data. NMR relaxation is the most widely used experimental method to obtain data on dynamics of proteins, but it is limited to relatively short timescales and to motions of backbone amides or in some cases (13)C-H vectors. By relating the experimental data to the all-atom picture obtained in molecular dynamics simulations, valuable insights on the interpretation of the experiment can be gained. We have estimated the internal dynamics and their timescales by calculating the generalized order parameters (O) for different time windows. We then calculate the quasiharmonic entropy (S) and compare it to the entropy calculated from the NMR-derived generalized order parameter of the amide vectors. Special emphasis is put on characterizing dynamics that are not expressed through the motions of the amide group. The NMR and MD methods suffer from complementary limitations, with NMR being restricted to local vectors and dynamics on a timescale determined by the rotational diffusion of the solute, while in simulations, it may be difficult to obtain sufficient sampling to ensure convergence of the results. We also evaluate the amount of sampling obtained with molecular dynamics simulations and how it is affected by the length of individual simulations, by clustering of the sampled conformations. We find that two structural turns act as hinges, allowing the α helix between them to undergo large, long timescale motions that cannot be detected in the time window of the NMR dipolar relaxation experiments. We also show that the entropy obtained from the amide vector does not account for correlated motions of adjacent residues. Finally, we show that the sampling in a total of 100 ns molecular dynamics simulation can be increased by around 50%, by dividing the

  8. A hierarchy of time-scales and the brain.

    PubMed

    Kiebel, Stefan J; Daunizeau, Jean; Friston, Karl J

    2008-11-01

    In this paper, we suggest that cortical anatomy recapitulates the temporal hierarchy that is inherent in the dynamics of environmental states. Many aspects of brain function can be understood in terms of a hierarchy of temporal scales at which representations of the environment evolve. The lowest level of this hierarchy corresponds to fast fluctuations associated with sensory processing, whereas the highest levels encode slow contextual changes in the environment, under which faster representations unfold. First, we describe a mathematical model that exploits the temporal structure of fast sensory input to track the slower trajectories of their underlying causes. This model of sensory encoding or perceptual inference establishes a proof of concept that slowly changing neuronal states can encode the paths or trajectories of faster sensory states. We then review empirical evidence that suggests that a temporal hierarchy is recapitulated in the macroscopic organization of the cortex. This anatomic-temporal hierarchy provides a comprehensive framework for understanding cortical function: the specific time-scale that engages a cortical area can be inferred by its location along a rostro-caudal gradient, which reflects the anatomical distance from primary sensory areas. This is most evident in the prefrontal cortex, where complex functions can be explained as operations on representations of the environment that change slowly. The framework provides predictions about, and principled constraints on, cortical structure-function relationships, which can be tested by manipulating the time-scales of sensory input.

  9. Reduced linear noise approximation for biochemical reaction networks with time-scale separation: The stochastic tQSSA+

    NASA Astrophysics Data System (ADS)

    Herath, Narmada; Del Vecchio, Domitilla

    2018-03-01

    Biochemical reaction networks often involve reactions that take place on different time scales, giving rise to "slow" and "fast" system variables. This property is widely used in the analysis of systems to obtain dynamical models with reduced dimensions. In this paper, we consider stochastic dynamics of biochemical reaction networks modeled using the Linear Noise Approximation (LNA). Under time-scale separation conditions, we obtain a reduced-order LNA that approximates both the slow and fast variables in the system. We mathematically prove that the first and second moments of this reduced-order model converge to those of the full system as the time-scale separation becomes large. These mathematical results, in particular, provide a rigorous justification to the accuracy of LNA models derived using the stochastic total quasi-steady state approximation (tQSSA). Since, in contrast to the stochastic tQSSA, our reduced-order model also provides approximations for the fast variable stochastic properties, we term our method the "stochastic tQSSA+". Finally, we demonstrate the application of our approach on two biochemical network motifs found in gene-regulatory and signal transduction networks.

  10. The predictability of a lake phytoplankton community, over time-scales of hours to years.

    PubMed

    Thomas, Mridul K; Fontana, Simone; Reyes, Marta; Kehoe, Michael; Pomati, Francesco

    2018-05-01

    Forecasting changes to ecological communities is one of the central challenges in ecology. However, nonlinear dependencies, biotic interactions and data limitations have limited our ability to assess how predictable communities are. Here, we used a machine learning approach and environmental monitoring data (biological, physical and chemical) to assess the predictability of phytoplankton cell density in one lake across an unprecedented range of time-scales. Communities were highly predictable over hours to months: model R 2 decreased from 0.89 at 4 hours to 0.74 at 1 month, and in a long-term dataset lacking fine spatial resolution, from 0.46 at 1 month to 0.32 at 10 years. When cyanobacterial and eukaryotic algal cell densities were examined separately, model-inferred environmental growth dependencies matched laboratory studies, and suggested novel trade-offs governing their competition. High-frequency monitoring and machine learning can set prediction targets for process-based models and help elucidate the mechanisms underlying ecological dynamics. © 2018 John Wiley & Sons Ltd/CNRS.

  11. Accessible methods for the dynamic time-scale decomposition of biochemical systems.

    PubMed

    Surovtsova, Irina; Simus, Natalia; Lorenz, Thomas; König, Artjom; Sahle, Sven; Kummer, Ursula

    2009-11-01

    The growing complexity of biochemical models asks for means to rationally dissect the networks into meaningful and rather independent subnetworks. Such foregoing should ensure an understanding of the system without any heuristics employed. Important for the success of such an approach is its accessibility and the clarity of the presentation of the results. In order to achieve this goal, we developed a method which is a modification of the classical approach of time-scale separation. This modified method as well as the more classical approach have been implemented for time-dependent application within the widely used software COPASI. The implementation includes different possibilities for the representation of the results including 3D-visualization. The methods are included in COPASI which is free for academic use and available at www.copasi.org. irina.surovtsova@bioquant.uni-heidelberg.de Supplementary data are available at Bioinformatics online.

  12. Sea level oscillations over minute timescales: a global perspective

    NASA Astrophysics Data System (ADS)

    Vilibic, Ivica; Sepic, Jadranka

    2016-04-01

    Sea level oscillations occurring over minutes to a few hours are an important contributor to sea level extremes, and a knowledge on their behaviour is essential for proper quantification of coastal marine hazards. Tsunamis, meteotsunamis, infra-gravity waves and harbour oscillations may even dominate sea level extremes in certain areas and thus pose a great danger for humans and coastal infrastructure. Aside for tsunamis, which are, due to their enormous impact to the coastlines, a well-researched phenomena, the importance of other high-frequency oscillations to the sea level extremes is still underrated, as no systematic long-term measurements have been carried out at a minute timescales. Recently, Intergovernmental Oceanographic Commission (IOC) established Sea Level Monitoring Facility portal (http://www.ioc-sealevelmonitoring.org), making 1-min sea level data publicly available for several hundred tide gauge sites in the World Ocean. Thereafter, a global assessment of oscillations over tsunami timescales become possible; however, the portal contains raw sea level data only, being unchecked for spikes, shifts, drifts and other malfunctions of instruments. We present a quality assessment of these data, estimates of sea level variances and contributions of high-frequency processes to the extremes throughout the World Ocean. This is accompanied with assessment of atmospheric conditions and processes which generate intense high-frequency oscillations.

  13. A BARYONIC EFFECT ON THE MERGER TIMESCALE OF GALAXY CLUSTERS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Congyao; Yu, Qingjuan; Lu, Youjun, E-mail: yuqj@pku.edu.cn

    2016-04-01

    Accurate estimation of the merger timescales of galaxy clusters is important for understanding the cluster merger process and further understanding the formation and evolution of the large-scale structure of the universe. In this paper, we explore a baryonic effect on the merger timescale of galaxy clusters by using hydrodynamical simulations. We find that the baryons play an important role in accelerating the merger process. The merger timescale decreases upon increasing the gas fraction of galaxy clusters. For example, the merger timescale is shortened by a factor of up to 3 for merging clusters with gas fractions of 0.15, compared withmore » the timescale obtained with 0 gas fractions. The baryonic effect is significant for a wide range of merger parameters and is particularly more significant for nearly head-on mergers and high merging velocities. The baryonic effect on the merger timescale of galaxy clusters is expected to have an impact on the structure formation in the universe, such as the cluster mass function and massive substructures in galaxy clusters, and a bias of “no-gas” may exist in the results obtained from the dark matter-only cosmological simulations.« less

  14. Ultra-Soft PDMS-Based Magnetoactive Elastomers as Dynamic Cell Culture Substrata

    PubMed Central

    Mayer, Matthias; Rabindranath, Raman; Börner, Juliane; Hörner, Eva; Bentz, Alexander; Salgado, Josefina; Han, Hong; Böse, Holger; Probst, Jörn; Shamonin, Mikhail; Monkman, Gareth J.; Schlunck, Günther

    2013-01-01

    Mechanical cues such as extracellular matrix stiffness and movement have a major impact on cell differentiation and function. To replicate these biological features in vitro, soft substrata with tunable elasticity and the possibility for controlled surface translocation are desirable. Here we report on the use of ultra-soft (Young’s modulus <100 kPa) PDMS-based magnetoactive elastomers (MAE) as suitable cell culture substrata. Soft non-viscous PDMS (<18 kPa) is produced using a modified extended crosslinker. MAEs are generated by embedding magnetic microparticles into a soft PDMS matrix. Both substrata yield an elasticity-dependent (14 vs. 100 kPa) modulation of α-smooth muscle actin expression in primary human fibroblasts. To allow for static or dynamic control of MAE material properties, we devise low magnetic field (≈40 mT) stimulation systems compatible with cell-culture environments. Magnetic field-instigated stiffening (14 to 200 kPa) of soft MAE enhances the spreading of primary human fibroblasts and decreases PAX-7 transcription in human mesenchymal stem cells. Pulsatile MAE movements are generated using oscillating magnetic fields and are well tolerated by adherent human fibroblasts. This MAE system provides spatial and temporal control of substratum material characteristics and permits novel designs when used as dynamic cell culture substrata or cell culture-coated actuator in tissue engineering applications or biomedical devices. PMID:24204603

  15. Long-Distance Rescue and Slow Extinction Dynamics Govern Multiscale Metapopulations.

    PubMed

    Huth, Géraldine; Haegeman, Bart; Pitard, Estelle; Munoz, François

    2015-10-01

    Rare long-distance dispersal is known to be critical for species dynamics, but how the interplay between short- and long-distance colonization influences regional persistence in a fragmented habitat remains poorly understood. We propose a metapopulation model that combines local colonization within habitat islands and long-distance colonization between islands. We study how regional occupancy dynamics are affected by the multiscale colonization process. We find that the island size distribution (ISD) is a key driver of the long-term occupancy dynamics. When the ISD is heterogeneous-that is, when the size of islands is variable-we show that extinction dynamics become very slow. We demonstrate that this behavior is unrelated to the well-known extinction debt near the critical extinction threshold. Hence, this finding questions the equivalence between extinction debt and critical transitions in the context of metapopulation collapse. Furthermore, we show that long-distance colonization can rescue small islands from extinction and sustain a steady regional occupancy. These results provide novel theoretical and practical insights into extinction dynamics and persistence in fragmented habitats and are thus relevant for the design of conservation strategies.

  16. The slow-scale linear noise approximation: an accurate, reduced stochastic description of biochemical networks under timescale separation conditions

    PubMed Central

    2012-01-01

    Background It is well known that the deterministic dynamics of biochemical reaction networks can be more easily studied if timescale separation conditions are invoked (the quasi-steady-state assumption). In this case the deterministic dynamics of a large network of elementary reactions are well described by the dynamics of a smaller network of effective reactions. Each of the latter represents a group of elementary reactions in the large network and has associated with it an effective macroscopic rate law. A popular method to achieve model reduction in the presence of intrinsic noise consists of using the effective macroscopic rate laws to heuristically deduce effective probabilities for the effective reactions which then enables simulation via the stochastic simulation algorithm (SSA). The validity of this heuristic SSA method is a priori doubtful because the reaction probabilities for the SSA have only been rigorously derived from microscopic physics arguments for elementary reactions. Results We here obtain, by rigorous means and in closed-form, a reduced linear Langevin equation description of the stochastic dynamics of monostable biochemical networks in conditions characterized by small intrinsic noise and timescale separation. The slow-scale linear noise approximation (ssLNA), as the new method is called, is used to calculate the intrinsic noise statistics of enzyme and gene networks. The results agree very well with SSA simulations of the non-reduced network of elementary reactions. In contrast the conventional heuristic SSA is shown to overestimate the size of noise for Michaelis-Menten kinetics, considerably under-estimate the size of noise for Hill-type kinetics and in some cases even miss the prediction of noise-induced oscillations. Conclusions A new general method, the ssLNA, is derived and shown to correctly describe the statistics of intrinsic noise about the macroscopic concentrations under timescale separation conditions. The ssLNA provides a

  17. Determination of Arctic sea ice variability modes on interannual timescales via nonhierarchical clustering

    NASA Astrophysics Data System (ADS)

    Fučkar, Neven-Stjepan; Guemas, Virginie; Massonnet, François; Doblas-Reyes, Francisco

    2015-04-01

    Over the modern observational era, the northern hemisphere sea ice concentration, age and thickness have experienced a sharp long-term decline superimposed with strong internal variability. Hence, there is a crucial need to identify robust patterns of Arctic sea ice variability on interannual timescales and disentangle them from the long-term trend in noisy datasets. The principal component analysis (PCA) is a versatile and broadly used method for the study of climate variability. However, the PCA has several limiting aspects because it assumes that all modes of variability have symmetry between positive and negative phases, and suppresses nonlinearities by using a linear covariance matrix. Clustering methods offer an alternative set of dimension reduction tools that are more robust and capable of taking into account possible nonlinear characteristics of a climate field. Cluster analysis aggregates data into groups or clusters based on their distance, to simultaneously minimize the distance between data points in a given cluster and maximize the distance between the centers of the clusters. We extract modes of Arctic interannual sea-ice variability with nonhierarchical K-means cluster analysis and investigate the mechanisms leading to these modes. Our focus is on the sea ice thickness (SIT) as the base variable for clustering because SIT holds most of the climate memory for variability and predictability on interannual timescales. We primarily use global reconstructions of sea ice fields with a state-of-the-art ocean-sea-ice model, but we also verify the robustness of determined clusters in other Arctic sea ice datasets. Applied cluster analysis over the 1958-2013 period shows that the optimal number of detrended SIT clusters is K=3. Determined SIT cluster patterns and their time series of occurrence are rather similar between different seasons and months. Two opposite thermodynamic modes are characterized with prevailing negative or positive SIT anomalies over the

  18. Conformational Dynamics Guides Coherent Exciton Migration in Conjugated Polymer Materials: First-Principles Quantum Dynamical Study

    NASA Astrophysics Data System (ADS)

    Binder, Robert; Lauvergnat, David; Burghardt, Irene

    2018-06-01

    We report on high-dimensional quantum dynamical simulations of photoinduced exciton migration in a single-chain oligothiophene segment, in view of elucidating the controversial nature of the elementary exciton transport steps in semiconducting polymers. A novel first-principles parametrized Frenkel J aggregate Hamiltonian is employed that goes significantly beyond the standard Frenkel-Holstein Hamiltonian. Departing from a nonequilibrium state created by photoexcitation, these simulations provide evidence of an ultrafast two-timescale process at low temperatures, involving exciton-polaron formation within tens of femtoseconds (fs), followed by torsional relaxation on an ˜400 fs timescale. The second step is the driving force for exciton migration, as initial conjugation breaks are removed by dynamical planarization. The quantum coherent nature of the elementary exciton migration step is consistent with experimental observations highlighting the correlated and vibrationally coherent nature of the dynamics on ultrafast timescales.

  19. Conformational Dynamics Guides Coherent Exciton Migration in Conjugated Polymer Materials: First-Principles Quantum Dynamical Study.

    PubMed

    Binder, Robert; Lauvergnat, David; Burghardt, Irene

    2018-06-01

    We report on high-dimensional quantum dynamical simulations of photoinduced exciton migration in a single-chain oligothiophene segment, in view of elucidating the controversial nature of the elementary exciton transport steps in semiconducting polymers. A novel first-principles parametrized Frenkel J aggregate Hamiltonian is employed that goes significantly beyond the standard Frenkel-Holstein Hamiltonian. Departing from a nonequilibrium state created by photoexcitation, these simulations provide evidence of an ultrafast two-timescale process at low temperatures, involving exciton-polaron formation within tens of femtoseconds (fs), followed by torsional relaxation on an ∼400  fs timescale. The second step is the driving force for exciton migration, as initial conjugation breaks are removed by dynamical planarization. The quantum coherent nature of the elementary exciton migration step is consistent with experimental observations highlighting the correlated and vibrationally coherent nature of the dynamics on ultrafast timescales.

  20. Partitioning controls on Amazon forest photosynthesis between environmental and biotic factors at hourly to interannual timescales.

    PubMed

    Wu, Jin; Guan, Kaiyu; Hayek, Matthew; Restrepo-Coupe, Natalia; Wiedemann, Kenia T; Xu, Xiangtao; Wehr, Richard; Christoffersen, Bradley O; Miao, Guofang; da Silva, Rodrigo; de Araujo, Alessandro C; Oliviera, Raimundo C; Camargo, Plinio B; Monson, Russell K; Huete, Alfredo R; Saleska, Scott R

    2017-03-01

    Gross ecosystem productivity (GEP) in tropical forests varies both with the environment and with biotic changes in photosynthetic infrastructure, but our understanding of the relative effects of these factors across timescales is limited. Here, we used a statistical model to partition the variability of seven years of eddy covariance-derived GEP in a central Amazon evergreen forest into two main causes: variation in environmental drivers (solar radiation, diffuse light fraction, and vapor pressure deficit) that interact with model parameters that govern photosynthesis and biotic variation in canopy photosynthetic light-use efficiency associated with changes in the parameters themselves. Our fitted model was able to explain most of the variability in GEP at hourly (R 2  = 0.77) to interannual (R 2  = 0.80) timescales. At hourly timescales, we found that 75% of observed GEP variability could be attributed to environmental variability. When aggregating GEP to the longer timescales (daily, monthly, and yearly), however, environmental variation explained progressively less GEP variability: At monthly timescales, it explained only 3%, much less than biotic variation in canopy photosynthetic light-use efficiency, which accounted for 63%. These results challenge modeling approaches that assume GEP is primarily controlled by the environment at both short and long timescales. Our approach distinguishing biotic from environmental variability can help to resolve debates about environmental limitations to tropical forest photosynthesis. For example, we found that biotically regulated canopy photosynthetic light-use efficiency (associated with leaf phenology) increased with sunlight during dry seasons (consistent with light but not water limitation of canopy development) but that realized GEP was nonetheless lower relative to its potential efficiency during dry than wet seasons (consistent with water limitation of photosynthesis in given assemblages of leaves). This work

  1. The role of localised Ultra-Low Frequency waves in energetic electron precipitation

    NASA Astrophysics Data System (ADS)

    Rae, J.; Murphy, K. R.; Watt, C.; Mann, I. R.; Ozeke, L.; Halford, A. J.; Sibeck, D. G.; Clilverd, M. A.; Rodger, C. J.; Degeling, A. W.; Singer, H. J.

    2016-12-01

    Electromagnetic waves play pivotal roles in radiation belt dynamics through a variety of different means. Typically, Ultra-Low Frequency (ULF) waves have historically been invoked for radial diffusive transport leading to both acceleration and loss of outer radiation belt electrons. Very-Low Frequency (VLF) and Extremely-Low Frequency (ELF) waves are generally thought to provide a mechanism for localized acceleration and loss through precipitation into the ionosphere. In this study we present a new mechanism for electron loss through precipitation into the ionosphere due to direct modulation of the loss cone via localized compressional ULF waves. Observational evidence is presented demonstrating that modulation of the equatorial loss cone can occur via localized compressional wave activity. We then perform statistical computations of the probability distribution to determine how likely a given magnetic perturbation would produce a given percentage change in the bounce loss-cone (BLC). We discuss the ramifications of the action of coherent, localized compressional ULF waves on drifting electron populations; their precipitation response can be a complex interplay between electron energy, the shape of the phase space density profile at pitch angles close to the loss cone, ionospheric decay timescales, and the time-dependence of the electron source. We present a case study of compressional wave activity in tandem with riometer and balloon-borne electron precipitation across keV-MeV energies to demonstrate that the experimental measurements can be explained by our new enhanced loss cone mechanism. We determine that the two pivotal components not usually considered are localized ULF wave fields and ionospheric decay timescales. We conclude that ULF wave modulation of the loss cone is a viable candidate for direct precipitation of radiation belt electrons without any additional requirement for gyroresonant wave-particle interaction. Additional mechanisms would be

  2. Dynamics of Long-period Comets

    NASA Technical Reports Server (NTRS)

    Weissman, P. R.

    1985-01-01

    Dynamical studies of the origin and evolution of long period comets in the Oort cloud during the past year have concentrated on four areas: (1) interpretation of IRAS observations of dust shells around Vega and some 40 other main sequence stars as evidence for cometary clouds around each of these stars; (2) the dynamical plausibility of an unseen solar companion star orbiting in the Oort cloud and causing periodic cometary showers which result in biological extinction events on the earth; (3) a review of the current hypotheses for cometary formation with particular attention to how each mechanism supplies the required mass of comets to the Oort cloud; and (4) development of new dynamics software to simulate the passage of individual stars directly through the Oort cloud. Each of these efforts is described in detail.

  3. Intrinsic vs. spurious long-range memory in high-frequency records of environmental radioactivity. Critical re-assessment and application to indoor 222Rn concentrations from Coimbra, Portugal

    NASA Astrophysics Data System (ADS)

    Donner, R. V.; Potirakis, S. M.; Barbosa, S. M.; Matos, J. A. O.; Pereira, A. J. S. C.; Neves, L. J. P. F.

    2015-05-01

    The presence or absence of long-range correlations in the environmental radioactivity fluctuations has recently attracted considerable interest. Among a multiplicity of practically relevant applications, identifying and disentangling the environmental factors controlling the variable concentrations of the radioactive noble gas radon is important for estimating its effect on human health and the efficiency of possible measures for reducing the corresponding exposition. In this work, we present a critical re-assessment of a multiplicity of complementary methods that have been previously applied for evaluating the presence of long-range correlations and fractal scaling in environmental radon variations with a particular focus on the specific properties of the underlying time series. As an illustrative case study, we subsequently re-analyze two high-frequency records of indoor radon concentrations from Coimbra, Portugal, each of which spans several weeks of continuous measurements at a high temporal resolution of five minutes.Our results reveal that at the study site, radon concentrations exhibit complex multi-scale dynamics with qualitatively different properties at different time-scales: (i) essentially white noise in the high-frequency part (up to time-scales of about one hour), (ii) spurious indications of a non-stationary, apparently long-range correlated process (at time scales between some hours and one day) arising from marked periodic components, and (iii) low-frequency variability indicating a true long-range dependent process. In the presence of such multi-scale variability, common estimators of long-range memory in time series are prone to fail if applied to the raw data without previous separation of time-scales with qualitatively different dynamics.

  4. Long-Range Coulomb Effect in Intense Laser-Driven Photoelectron Dynamics.

    PubMed

    Quan, Wei; Hao, XiaoLei; Chen, YongJu; Yu, ShaoGang; Xu, SongPo; Wang, YanLan; Sun, RenPing; Lai, XuanYang; Wu, ChengYin; Gong, QiHuang; He, XianTu; Liu, XiaoJun; Chen, Jing

    2016-06-03

    In strong field atomic physics community, long-range Coulomb interaction has for a long time been overlooked and its significant role in intense laser-driven photoelectron dynamics eluded experimental observations. Here we report an experimental investigation of the effect of long-range Coulomb potential on the dynamics of near-zero-momentum photoelectrons produced in photo-ionization process of noble gas atoms in intense midinfrared laser pulses. By exploring the dependence of photoelectron distributions near zero momentum on laser intensity and wavelength, we unambiguously demonstrate that the long-range tail of the Coulomb potential (i.e., up to several hundreds atomic units) plays an important role in determining the photoelectron dynamics after the pulse ends.

  5. Long-Range Coulomb Effect in Intense Laser-Driven Photoelectron Dynamics

    PubMed Central

    Quan, Wei; Hao, XiaoLei; Chen, YongJu; Yu, ShaoGang; Xu, SongPo; Wang, YanLan; Sun, RenPing; Lai, XuanYang; Wu, ChengYin; Gong, QiHuang; He, XianTu; Liu, XiaoJun; Chen, Jing

    2016-01-01

    In strong field atomic physics community, long-range Coulomb interaction has for a long time been overlooked and its significant role in intense laser-driven photoelectron dynamics eluded experimental observations. Here we report an experimental investigation of the effect of long-range Coulomb potential on the dynamics of near-zero-momentum photoelectrons produced in photo-ionization process of noble gas atoms in intense midinfrared laser pulses. By exploring the dependence of photoelectron distributions near zero momentum on laser intensity and wavelength, we unambiguously demonstrate that the long-range tail of the Coulomb potential (i.e., up to several hundreds atomic units) plays an important role in determining the photoelectron dynamics after the pulse ends. PMID:27256904

  6. Chimeric β-Lactamases: Global Conservation of Parental Function and Fast Time-Scale Dynamics with Increased Slow Motions

    PubMed Central

    Clouthier, Christopher M.; Morin, Sébastien; Gobeil, Sophie M. C.; Doucet, Nicolas; Blanchet, Jonathan; Nguyen, Elisabeth; Gagné, Stéphane M.; Pelletier, Joelle N.

    2012-01-01

    Enzyme engineering has been facilitated by recombination of close homologues, followed by functional screening. In one such effort, chimeras of two class-A β-lactamases – TEM-1 and PSE-4 – were created according to structure-guided protein recombination and selected for their capacity to promote bacterial proliferation in the presence of ampicillin (Voigt et al., Nat. Struct. Biol. 2002 9:553). To provide a more detailed assessment of the effects of protein recombination on the structure and function of the resulting chimeric enzymes, we characterized a series of functional TEM-1/PSE-4 chimeras possessing between 17 and 92 substitutions relative to TEM-1 β-lactamase. Circular dichroism and thermal scanning fluorimetry revealed that the chimeras were generally well folded. Despite harbouring important sequence variation relative to either of the two ‘parental’ β-lactamases, the chimeric β-lactamases displayed substrate recognition spectra and reactivity similar to their most closely-related parent. To gain further insight into the changes induced by chimerization, the chimera with 17 substitutions was investigated by NMR spin relaxation. While high order was conserved on the ps-ns timescale, a hallmark of class A β-lactamases, evidence of additional slow motions on the µs-ms timescale was extracted from model-free calculations. This is consistent with the greater number of resonances that could not be assigned in this chimera relative to the parental β-lactamases, and is consistent with this well-folded and functional chimeric β-lactamase displaying increased slow time-scale motions. PMID:23284969

  7. The INTEGRAL long monitoring of persistent ultra compact X-ray bursters

    NASA Astrophysics Data System (ADS)

    Fiocchi, M.; Bazzano, A.; Ubertini, P.; Bird, A. J.; Natalucci, L.; Sguera, V.

    2008-12-01

    Context: The combination of compact objects, short period variability and peculiar chemical composition of the ultra compact X-ray binaries make up a very interesting laboratory to study accretion processes and thermonuclear burning on the neutron star surface. Improved large optical telescopes and more sensitive X-ray satellites have increased the number of known ultra compact X-ray binaries allowing their study with unprecedented detail. Aims: We analyze the average properties common to all ultra compact bursters observed by INTEGRAL from 0.2 keV to 150 keV. Methods: We have performed a systematic analysis of the INTEGRAL public data and Key-Program proprietary observations of a sample of the ultra compact X-ray binaries. In order to study their average properties in a very broad energy band, we combined INTEGRAL with BeppoSAX and SWIFT data whenever possible. For sources not showing any significant flux variations along the INTEGRAL monitoring, we build the average spectrum by combining all available data; in the case of variable fluxes, we use simultaneous INTEGRAL and SWIFT observations when available. Otherwise we compared IBIS and PDS data to check the variability and combine BeppoSAX with INTEGRAL /IBIS data. Results: All spectra are well represented by a two component model consisting of a disk-blackbody and Comptonised emission. The majority of these compact sources spend most of the time in a canonical low/hard state, with a dominating Comptonised component and accretion rate dot {M} lower than 10-9 {M⊙}/yr, not depending on the model used to fit the data. INTEGRAL is an ESA project with instruments and Science Data Center funded by ESA member states (especially the PI countries: Denmark, France, Germany, Italy, Switzerland, Spain), Czech Republic and Poland, and with the participation of Russia and the USA.

  8. Preliminary Analysis of the 30-m UltraBoom Flight Test

    NASA Technical Reports Server (NTRS)

    Agnes, Gregory S.; Abelson, Robert D.; Miyake, Robert; Lin, John K. H.; Welsh, Joe; Watson, Judith J.

    2005-01-01

    Future NASA missions require long, ultra-lightweight booms to enable solar sails, large sunshields, and other gossamer-type spacecraft structures. The space experiment discussed in this paper will flight validate the non-traditional ultra lightweight rigidizable, inflatable, isogrid structure utilizing graphite shape memory polymer (GR/SMP) called UltraBoom(TradeMark). The focus of this paper is the analysis of the 3-m ground test article. The primary objective of the mission is to show that a combination of ground testing and analysis can predict the on-orbit performance of an ultra lightweight boom that is scalable, predictable, and thermomechanically stable.

  9. Decadal to monthly timescales of magma transfer and reservoir growth at a caldera volcano.

    PubMed

    Druitt, T H; Costa, F; Deloule, E; Dungan, M; Scaillet, B

    2012-02-01

    Caldera-forming volcanic eruptions are low-frequency, high-impact events capable of discharging tens to thousands of cubic kilometres of magma explosively on timescales of hours to days, with devastating effects on local and global scales. Because no such eruption has been monitored during its long build-up phase, the precursor phenomena are not well understood. Geophysical signals obtained during recent episodes of unrest at calderas such as Yellowstone, USA, and Campi Flegrei, Italy, are difficult to interpret, and the conditions necessary for large eruptions are poorly constrained. Here we present a study of pre-eruptive magmatic processes and their timescales using chemically zoned crystals from the 'Minoan' caldera-forming eruption of Santorini volcano, Greece, which occurred in the late 1600s BC. The results provide insights into how rapidly large silicic systems may pass from a quiescent state to one on the edge of eruption. Despite the large volume of erupted magma (40-60 cubic kilometres), and the 18,000-year gestation period between the Minoan eruption and the previous major eruption, most crystals in the Minoan magma record processes that occurred less than about 100 years before the eruption. Recharge of the magma reservoir by large volumes of silicic magma (and some mafic magma) occurred during the century before eruption, and mixing between different silicic magma batches was still taking place during the final months. Final assembly of large silicic magma reservoirs may occur on timescales that are geologically very short by comparison with the preceding repose period, with major growth phases immediately before eruption. These observations have implications for the monitoring of long-dormant, but potentially active, caldera systems.

  10. The UltraLightweight Technology for Research in Astronomy (ULTRA) Project

    NASA Astrophysics Data System (ADS)

    Twarog, B. A.; Anthony-Twarog, B. J.; Shawl, S. J.; Hale, R.; Taghavi, R.; Fesen, R.; Etzel, P. B.; Martin, R.; Romeo, R.

    2004-12-01

    The collaborative focus of four academic departments (Univ. of Kansas Aerospace Engineering, Univ. of Kansas Physics & Astronomy, San Diego State University Astronomy and Dartmouth College Astronomy) and a private industry partner (Composite Mirror Applications, Inc.-CMA, Inc.) is a three-year plan to develop and test UltraLightweight Technology for Research in Astronomy (ULTRA). The ULTRA technology, using graphite fiber composites to fabricate mirrors and telescope structures, offers a versatile and cost-effective tool for optical astronomy, including the economical fabrication and operation of telescopes ranging from small (1m or smaller) aperture for education and research to extremely large (30m+) segmented telescopes (ELTs). The specific goal of this NSF-funded three-year Major Research Instrumentation project is to design, build, and test a 1m-class optical tube assembly (OTA) and mirrors constructed entirely from composites. In the first year of the project, the team has built and is field-testing two 0.4m prototypes to validate the optical surfaces and figures of the mirrors and to test and refine the structural dynamics of the OTA. Preparation for design and construction of the 1m telescope is underway. When completed in late 2005, the ULTRA telescope will be operated remotely from Mt. Laguna Observatory east of San Diego, where it will undergo a period of intensive optical and imaging tests. A 0.4m prototype OTA with mirrors (12 kg total weight) will be on display at the meeting. Support of this work by NSF through grants AST-0320784 and AST-0321247, NASA grant NCC5-600, the University of Kansas, and San Diego State University is gratefully acknowledged.

  11. The Exoplanet Migration Timescale from K2 Young Clusters

    NASA Astrophysics Data System (ADS)

    Rizzuto, Aaron

    A significant fraction of exoplanets orbit within 0.1 AU of their host star, with periods of <20 days. The discovery of these close-in planets has defied conventional models of planet formation and evolution based on our own solar system. It is widely accepted that these close-in planets did not form in such close proximity to their host stars (both rocky planets and hot Jupiters), but rather that dynamical or interactive processes caused them to migrate inwards from larger orbital semimajor axes and periods. There are multiple planet migration scenarios proposed in the literature, though it is unclear how much of the known planet population is attributable to each mechanism. Planetary migration models can be loosely divided into two categories: disk-driven migration and dynamical migration. Disk migration occurs over the lifetime of the protoplanetary disk (<5 Myr), while migration involving dynamical multi-body interactions operates on timescales of 100 Myr to 1Gyr, a lengthier process than disk migration. The K2 mission has measured planet formation timescales and migration pathways by sampling groups of stars at key ages. Over the past 10 campaigns, multiple groups of young stars have been observed by K2, ranging from the 10 Myr Upper Scorpius OB association, through the <120 Myr Pleiades cluster, to the ,600-800 Myr Hyades and Praesepe clusters. Upcoming data from more recent campaigns include the 2Myr Taurus region and significantly more Upper Scorpius members in C13 and 15. The frequency, orbital properties, and compositions of the exoplanet population in these samples of different age, with careful treatment of detection completeness, distinguish these scenarios of exoplanet migration as their host stars are settling onto the main sequence. We have pioneered efforts to identify transiting exoplanets in the K2 data for young clusters and moving groups, and have developed a new, highly complete, detrending algorithm for rotational induced variability that is

  12. Bounds on Energy Absorption and Prethermalization in Quantum Systems with Long-Range Interactions

    NASA Astrophysics Data System (ADS)

    Ho, Wen Wei; Protopopov, Ivan; Abanin, Dmitry A.

    2018-05-01

    Long-range interacting systems such as nitrogen vacancy centers in diamond and trapped ions serve as experimental setups to probe a range of nonequilibrium many-body phenomena. In particular, via driving, various effective Hamiltonians with physics potentially quite distinct from short-range systems can be realized. In this Letter, we derive general rigorous bounds on the linear response energy absorption rates of periodically driven systems of spins or fermions with long-range interactions that are sign changing and fall off as 1 /rα with α >d /2 . We show that the disorder averaged energy absorption rate at high temperatures decays exponentially with the driving frequency. This strongly suggests the presence of a prethermal plateau in which dynamics is governed by an effective, static Hamiltonian for long times, and we provide numerical evidence to support such a statement. Our results are relevant for understanding timescales of heating and new dynamical regimes described by effective Hamiltonians in such long-range systems.

  13. Historical data as a baseline for conservation: reconstructing long-term faunal extinction dynamics in Late Imperial–modern China

    PubMed Central

    Turvey, Samuel T.; Crees, Jennifer J.; Di Fonzo, Martina M. I.

    2015-01-01

    Extinction events typically represent extended processes of decline that cannot be reconstructed using short-term studies. Long-term archives are necessary to determine past baselines and the extent of human-caused biodiversity change, but the capacity of historical datasets to provide predictive power for conservation must be assessed within a robust analytical framework. Local Chinese gazetteers represent a more than 400-year country-level dataset containing abundant information on past environmental conditions and include extensive records of gibbons, which have a restricted present-day distribution but formerly occurred across much of China. Gibbons show pre-twentieth century range contraction, with significant fragmentation by the mid-eighteenth century and population loss escalating in the late nineteenth century. Isolated gibbon populations persisted for about 40 years before local extinction. Populations persisted for longer at higher elevations, and disappeared earlier from northern and eastern regions, with the biogeography of population loss consistent with the contagion model of range collapse in response to human demographic expansion spreading directionally across China. The long-term Chinese historical record can track extinction events and human interactions with the environment across much longer timescales than are usually addressed in ecology, contributing novel baselines for conservation and an increased understanding of extinction dynamics and species vulnerability or resilience to human pressures. PMID:26246553

  14. Social evolution and genetic interactions in the short and long term.

    PubMed

    Van Cleve, Jeremy

    2015-08-01

    The evolution of social traits remains one of the most fascinating and feisty topics in evolutionary biology even after half a century of theoretical research. W.D. Hamilton shaped much of the field initially with his 1964 papers that laid out the foundation for understanding the effect of genetic relatedness on the evolution of social behavior. Early theoretical investigations revealed two critical assumptions required for Hamilton's rule to hold in dynamical models: weak selection and additive genetic interactions. However, only recently have analytical approaches from population genetics and evolutionary game theory developed sufficiently so that social evolution can be studied under the joint action of selection, mutation, and genetic drift. We review how these approaches suggest two timescales for evolution under weak mutation: (i) a short-term timescale where evolution occurs between a finite set of alleles, and (ii) a long-term timescale where a continuum of alleles are possible and populations evolve continuously from one monomorphic trait to another. We show how Hamilton's rule emerges from the short-term analysis under additivity and how non-additive genetic interactions can be accounted for more generally. This short-term approach reproduces, synthesizes, and generalizes many previous results including the one-third law from evolutionary game theory and risk dominance from economic game theory. Using the long-term approach, we illustrate how trait evolution can be described with a diffusion equation that is a stochastic analogue of the canonical equation of adaptive dynamics. Peaks in the stationary distribution of the diffusion capture classic notions of convergence stability from evolutionary game theory and generally depend on the additive genetic interactions inherent in Hamilton's rule. Surprisingly, the peaks of the long-term stationary distribution can predict the effects of simple kinds of non-additive interactions. Additionally, the peaks

  15. Towards a robust and consistent middle Eocene astronomical timescale

    NASA Astrophysics Data System (ADS)

    Boulila, Slah; Vahlenkamp, Maximilian; De Vleeschouwer, David; Laskar, Jacques; Yamamoto, Yuhji; Pälike, Heiko; Kirtland Turner, Sandra; Sexton, Philip F.; Westerhold, Thomas; Röhl, Ursula

    2018-03-01

    Until now, the middle Eocene has remained a poorly constrained interval of efforts to produce an astrochronological timescale for the entire Cenozoic. This has given rise to a so-called "Eocene astronomical timescale gap" (Vandenberghe et al., 2012). A high-resolution astrochronological calibration for this interval has proven to be difficult to realize, mainly because carbonate-rich deep-marine sequences of this age are scarce. In this paper, we present records from middle Eocene carbonate-rich sequences from the North Atlantic Southeast Newfoundland Ridge (IODP Exp. 342, Sites U1408 and U1410), of which the cyclical sedimentary patterns allow for an orbital calibration of the geologic timescale between ∼38 and ∼48 Ma. These carbonate-rich cyclic sediments at Sites U1408 and U1410 were deposited as drift deposits and exhibit prominent lithological alternations (couplets) between greenish nannofossil-rich clay and white nannofossil ooze. The principal lithological couplet is driven by the obliquity of Earth's axial tilt, and the intensity of their expression is modulated by a cyclicity of about 173 kyr. This cyclicity corresponds to the interference of secular frequencies s3 and s6 (related to the precession of nodes of the Earth and Saturn, respectively). This 173-kyr obliquity amplitude modulation cycle is exceptionally well recorded in the XRF (X-ray fluorescence)-derived Ca/Fe ratio. In this work, we first demonstrate the stability of the (s3-s6) cycles using the latest astronomical solutions. Results show that this orbital component is stable back to at least 50 Ma, and can thus serve as a powerful geochronometer in the mid-Eocene portion of the Cenozoic timescale. We then exploit this potential by calibrating the geochronology of the recovered middle Eocene timescale between magnetic polarity Chrons C18n.1n and C21n. Comparison with previous timescales shows similarities, but also notable differences in durations of certain magnetic polarity chrons. We

  16. Optimization of Root Section for Ultra-long Steam Turbine Rotor Blade

    NASA Astrophysics Data System (ADS)

    Hála, Jindřich; Luxa, Martin; Šimurda, David; Bobčík, Marek; Novák, Ondřej; Rudas, Bartoloměj; Synáč, Jaroslav

    2018-04-01

    This study presents the comparison of aerodynamic performances of two successive designs of the root profiles for the ultra-long rotor blade equipped with a straight fir-tree dovetail. Since aerodynamic and strength requirements laid upon the root section design are contradictory, it is necessary to aerodynamically optimize the design within the limits given by the foremost strength requirements. The most limiting criterion of the static strength is the size of the blade cross-section, which is determined by the number of blades in a rotor and also by the shape and size of a blade dovetail. The aerodynamic design requires mainly the zero incidence angle at the inlet of a profile and in the ideal case ensures that the load does not exceed a limit load condition. Moreover, the typical root profile cascades are transonic with supersonic exit Mach number, therefore, the shape of a suction side and a trailing edge has to respect transonic expansion of a working gas. In this paper, the two variants of root section profile cascades are compared and the aerodynamic qualities of both variants are verified using CFD simulation and two mutually independent experimental methods of measurements (optical and pneumatic).

  17. Multiple time step integrators in ab initio molecular dynamics.

    PubMed

    Luehr, Nathan; Markland, Thomas E; Martínez, Todd J

    2014-02-28

    Multiple time-scale algorithms exploit the natural separation of time-scales in chemical systems to greatly accelerate the efficiency of molecular dynamics simulations. Although the utility of these methods in systems where the interactions are described by empirical potentials is now well established, their application to ab initio molecular dynamics calculations has been limited by difficulties associated with splitting the ab initio potential into fast and slowly varying components. Here we present two schemes that enable efficient time-scale separation in ab initio calculations: one based on fragment decomposition and the other on range separation of the Coulomb operator in the electronic Hamiltonian. We demonstrate for both water clusters and a solvated hydroxide ion that multiple time-scale molecular dynamics allows for outer time steps of 2.5 fs, which are as large as those obtained when such schemes are applied to empirical potentials, while still allowing for bonds to be broken and reformed throughout the dynamics. This permits computational speedups of up to 4.4x, compared to standard Born-Oppenheimer ab initio molecular dynamics with a 0.5 fs time step, while maintaining the same energy conservation and accuracy.

  18. Convective radiation fluid-dynamics: formation and early evolution of ultra low-mass objects

    NASA Astrophysics Data System (ADS)

    Wuchterl, G.

    2005-12-01

    The formation process of ultra low-mass objects is some kind of extension of the star formation process. The physical changes towards lower mass are discussed by investigating the collapse of cloud cores that are modelled as Bonnor-Ebert spheres. Their collapse is followed by solving the equations of fluid dynamics with radiation and a model of time-dependent convection that has been calibrated to the Sun. For a sequence of cloud-cores with 1 to 0.01 solar masses, evolutionary tracks and isochrones are shown in the mass-radius diagram, the Hertzsprung-Russel diagram and the effective temperature-surface gravity or Kiel diagram. The collapse and the early hydrostatic evolution to ages of few Ma are briefly discussed and compared to observations of objects in Upper Scorpius and the low-mass components of GG Tau.

  19. Combustion Dynamics and Control for Ultra Low Emissions in Aircraft Gas-Turbine Engines

    NASA Technical Reports Server (NTRS)

    DeLaat, John C.

    2011-01-01

    Future aircraft engines must provide ultra-low emissions and high efficiency at low cost while maintaining the reliability and operability of present day engines. The demands for increased performance and decreased emissions have resulted in advanced combustor designs that are critically dependent on efficient fuel/air mixing and lean operation. However, all combustors, but most notably lean-burning low-emissions combustors, are susceptible to combustion instabilities. These instabilities are typically caused by the interaction of the fluctuating heat release of the combustion process with naturally occurring acoustic resonances. These interactions can produce large pressure oscillations within the combustor and can reduce component life and potentially lead to premature mechanical failures. Active Combustion Control which consists of feedback-based control of the fuel-air mixing process can provide an approach to achieving acceptable combustor dynamic behavior while minimizing emissions, and thus can provide flexibility during the combustor design process. The NASA Glenn Active Combustion Control Technology activity aims to demonstrate active control in a realistic environment relevant to aircraft engines by providing experiments tied to aircraft gas turbine combustors. The intent is to allow the technology maturity of active combustion control to advance to eventual demonstration in an engine environment. Work at NASA Glenn has shown that active combustion control, utilizing advanced algorithms working through high frequency fuel actuation, can effectively suppress instabilities in a combustor which emulates the instabilities found in an aircraft gas turbine engine. Current efforts are aimed at extending these active control technologies to advanced ultra-low-emissions combustors such as those employing multi-point lean direct injection.

  20. Microsecond protein dynamics observed at the single-molecule level

    NASA Astrophysics Data System (ADS)

    Otosu, Takuhiro; Ishii, Kunihiko; Tahara, Tahei

    2015-07-01

    How polypeptide chains acquire specific conformations to realize unique biological functions is a central problem of protein science. Single-molecule spectroscopy, combined with fluorescence resonance energy transfer, is utilized to study the conformational heterogeneity and the state-to-state transition dynamics of proteins on the submillisecond to second timescales. However, observation of the dynamics on the microsecond timescale is still very challenging. This timescale is important because the elementary processes of protein dynamics take place and direct comparison between experiment and simulation is possible. Here we report a new single-molecule technique to reveal the microsecond structural dynamics of proteins through correlation of the fluorescence lifetime. This method, two-dimensional fluorescence lifetime correlation spectroscopy, is applied to clarify the conformational dynamics of cytochrome c. Three conformational ensembles and the microsecond transitions in each ensemble are indicated from the correlation signal, demonstrating the importance of quantifying microsecond dynamics of proteins on the folding free energy landscape.

  1. Microsecond protein dynamics observed at the single-molecule level

    PubMed Central

    Otosu, Takuhiro; Ishii, Kunihiko; Tahara, Tahei

    2015-01-01

    How polypeptide chains acquire specific conformations to realize unique biological functions is a central problem of protein science. Single-molecule spectroscopy, combined with fluorescence resonance energy transfer, is utilized to study the conformational heterogeneity and the state-to-state transition dynamics of proteins on the submillisecond to second timescales. However, observation of the dynamics on the microsecond timescale is still very challenging. This timescale is important because the elementary processes of protein dynamics take place and direct comparison between experiment and simulation is possible. Here we report a new single-molecule technique to reveal the microsecond structural dynamics of proteins through correlation of the fluorescence lifetime. This method, two-dimensional fluorescence lifetime correlation spectroscopy, is applied to clarify the conformational dynamics of cytochrome c. Three conformational ensembles and the microsecond transitions in each ensemble are indicated from the correlation signal, demonstrating the importance of quantifying microsecond dynamics of proteins on the folding free energy landscape. PMID:26151767

  2. The relationship between interannual and long-term cloud feedbacks

    DOE PAGES

    Zhou, Chen; Zelinka, Mark D.; Dessler, Andrew E.; ...

    2015-12-11

    The analyses of Coupled Model Intercomparison Project phase 5 simulations suggest that climate models with more positive cloud feedback in response to interannual climate fluctuations also have more positive cloud feedback in response to long-term global warming. Ensemble mean vertical profiles of cloud change in response to interannual and long-term surface warming are similar, and the ensemble mean cloud feedback is positive on both timescales. However, the average long-term cloud feedback is smaller than the interannual cloud feedback, likely due to differences in surface warming pattern on the two timescales. Low cloud cover (LCC) change in response to interannual andmore » long-term global surface warming is found to be well correlated across models and explains over half of the covariance between interannual and long-term cloud feedback. In conclusion, the intermodel correlation of LCC across timescales likely results from model-specific sensitivities of LCC to sea surface warming.« less

  3. Dynamic neutron scattering from conformational dynamics. I. Theory and Markov models

    NASA Astrophysics Data System (ADS)

    Lindner, Benjamin; Yi, Zheng; Prinz, Jan-Hendrik; Smith, Jeremy C.; Noé, Frank

    2013-11-01

    The dynamics of complex molecules can be directly probed by inelastic neutron scattering experiments. However, many of the underlying dynamical processes may exist on similar timescales, which makes it difficult to assign processes seen experimentally to specific structural rearrangements. Here, we show how Markov models can be used to connect structural changes observed in molecular dynamics simulation directly to the relaxation processes probed by scattering experiments. For this, a conformational dynamics theory of dynamical neutron and X-ray scattering is developed, following our previous approach for computing dynamical fingerprints of time-correlation functions [F. Noé, S. Doose, I. Daidone, M. Löllmann, J. Chodera, M. Sauer, and J. Smith, Proc. Natl. Acad. Sci. U.S.A. 108, 4822 (2011)]. Markov modeling is used to approximate the relaxation processes and timescales of the molecule via the eigenvectors and eigenvalues of a transition matrix between conformational substates. This procedure allows the establishment of a complete set of exponential decay functions and a full decomposition into the individual contributions, i.e., the contribution of every atom and dynamical process to each experimental relaxation process.

  4. Long timestep dynamics of peptides by the dynamics driver approach.

    PubMed

    Derreumaux, P; Schlick, T

    1995-04-01

    Previous experience with the Langevin/implicit-Euler scheme for dynamics ("LI") on model systems (butane, water) has shown that LI is numerically stable for timesteps in the 5-20 fs range but quenches high-frequency modes. To explore applications to polypeptides, we apply LI to model systems (several dipeptides, a tetrapeptide, and a 13-residue oligoalanine) and also develop a new dynamics driver approach ("DA"). The DA scheme, based on LI, addresses the important issue of proper sampling, which is unlikely to be solved by small-timestep integration methods or implicit methods with intrinsic damping at room temperature, such as LI. Equilibrium averages, time-dependent molecular properties, and sampling trends at room temperature are reported for both LI and DA dynamics simulations, which are then compared to those generated by a standard explicit discretization of the Langevin equation with a 1 fs timestep. We find that LI's quenching effects are severe on both the fast and slow (due to vibrational coupling) frequency modes of all-atom polypeptides and lead to more restricted dynamics at moderate timesteps (40 fs). The DA approach empirically counteracts these damping effects by adding random atomic perturbations to the coordinates at each step (before the minimization of a dynamics function). By restricting the energetic fluctuations and controlling the kinetic energy, we are able with a 60 fs timestep to generate continuous trajectories that sample more of the relevant conformational space and also reproduce reasonably Boltzmann statistics. Although the timescale for transition may be accelerated by the DA approach, the transitional information obtained for the alanine dipeptide and the tetrapeptide is consistent with that obtained by several other theoretical approaches that focus specifically on the determination of pathways. While the trajectory for oligoalanine by the explicit scheme over the nanosecond timeframe remains in the vicinity of the full alpha R

  5. Transversely polarized sub-diffraction optical needle with ultra-long depth of focus

    NASA Astrophysics Data System (ADS)

    Guan, Jian; Lin, Jie; Chen, Chen; Ma, Yuan; Tan, Jiubin; Jin, Peng

    2017-12-01

    We generated purely transversely polarized sub-diffraction optical needles with ultra-long depth of focus (DOF) by focusing azimuthally polarized (AP) beams that were modulated by a vortex 0-2 π phase plate and binary phase diffraction optical elements (DOEs). The concentric belts' radii of the DOEs were optimized by a hybrid genetic particle swarm optimization (HGPSO) algorithm. For the focusing system with the numerical aperture (NA) of 0.95, an optical needle with the full width at half maximum (FWHM) of 0.40 λ and the DOF of 6.23 λ was generated. Similar optical needles were also generated by binary phase DOEs with different belts. The results demonstrated that the binary phase DOEs could achieve smaller FWHMs and longer DOFs simultaneously. The generated needles were circularly polarized on the z-axis and there were no longitudinally polarized components in the focal fields. The radius fabrication errors of a DOE have little effect on the optical needle produced by itself. The generated optical needles can be applied to the fields of photolithography, high-density optical data storage, microscope imaging and particle trapping.

  6. Agulhas leakage dynamics affects decadal variability in Atlantic overturning circulation.

    PubMed

    Biastoch, A; Böning, C W; Lutjeharms, J R E

    2008-11-27

    Predicting the evolution of climate over decadal timescales requires a quantitative understanding of the dynamics that govern the meridional overturning circulation (MOC). Comprehensive ocean measurement programmes aiming to monitor MOC variations have been established in the subtropical North Atlantic (RAPID, at latitude 26.5 degrees N, and MOVE, at latitude 16 degrees N) and show strong variability on intraseasonal to interannual timescales. Observational evidence of longer-term changes in MOC transport remains scarce, owing to infrequent sampling of transoceanic sections over past decades. Inferences based on long-term sea surface temperature records, however, supported by model simulations, suggest a variability with an amplitude of +/-1.5-3 Sv (1 Sv = 10(6) m(3) s(-1)) on decadal timescales in the subtropics. Such variability has been attributed to variations of deep water formation in the sub-arctic Atlantic, particularly the renewal rate of Labrador Sea Water. Here we present results from a model simulation that suggest an additional influence on decadal MOC variability having a Southern Hemisphere origin: dynamic signals originating in the Agulhas leakage region at the southern tip of Africa. These contribute a MOC signal in the tropical and subtropical North Atlantic that is of the same order of magnitude as the northern source. A complete rationalization of observed MOC changes therefore also requires consideration of signals arriving from the south.

  7. Efficient coding and detection of ultra-long IDs for visible light positioning systems.

    PubMed

    Zhang, Hualong; Yang, Chuanchuan

    2018-05-14

    Visible light positioning (VLP) is a promising technique to complement Global Navigation Satellite System (GNSS) such as Global positioning system (GPS) and BeiDou Navigation Satellite System (BDS) which features the advantage of low-cost and high accuracy. The situation becomes even more crucial for indoor environments, where satellite signals are weak or even unavailable. For large-scale application of VLP, there would be a considerable number of Light emitting diode (LED) IDs, which bring forward the demand of long LED ID detection. In particular, to provision indoor localization globally, a convenient way is to program a unique ID into each LED during manufacture. This poses a big challenge for image sensors, such as the CMOS camera in everybody's hands since the long ID covers the span of multiple frames. In this paper, we investigate the detection of ultra-long ID using rolling shutter cameras. By analyzing the pattern of data loss in each frame, we proposed a novel coding technique to improve the efficiency of LED ID detection. We studied the performance of Reed-Solomon (RS) code in this system and designed a new coding method which considered the trade-off between performance and decoding complexity. Coding technique decreases the number of frames needed in data processing, significantly reduces the detection time, and improves the accuracy of detection. Numerical and experimental results show that the detected LED ID can be much longer with the coding technique. Besides, our proposed coding method is proved to achieve a performance close to that of RS code while the decoding complexity is much lower.

  8. Variability of fire emissions on interannual to multi-decadal timescales in two Earth System models

    NASA Astrophysics Data System (ADS)

    Ward, D. S.; Shevliakova, E.; Malyshev, S.; Lamarque, J.-F.; Wittenberg, A. T.

    2016-12-01

    Connections between wildfires and modes of variability in climate are sought as a means for predicting fire activity on interannual to multi-decadal timescales. Several fire drivers, such as temperature and local drought index, have been shown to vary on these timescales, and analysis of tree-ring data suggests covariance between fires and climate oscillation indices in some regions. However, the shortness of the satellite record of global fire events limits investigations on larger spatial scales. Here we explore the interplay between climate variability and wildfire emissions with the preindustrial long control numerical experiments and historical ensembles of CESM1 and the NOAA/GFDL ESM2Mb. We find that interannual variability in fires is underpredicted in both Earth System models (ESMs) compared to present day fire emission inventories. Modeled fire emissions respond to the El Niño/southern oscillation (ENSO) and Pacific decadal oscillation (PDO) with increases in southeast Asia and boreal North America emissions, and decreases in southern North America and Sahel emissions, during the ENSO warm phase in both ESMs, and the PDO warm phase in CESM1. Additionally, CESM1 produces decreases in boreal northern hemisphere fire emissions for the warm phase of the Atlantic Meridional Oscillation. Through analysis of the long control simulations, we show that the 20th century trends in both ESMs are statistically significant, meaning that the signal of anthropogenic activity on fire emissions over this time period is detectable above the annual to decadal timescale noise. However, the trends simulated by the two ESMs are of opposite sign (CESM1 decreasing, ESM2Mb increasing), highlighting the need for improved understanding, proxy observations, and modeling to resolve this discrepancy.

  9. The Soft X-ray View of Ultra Fast Outflows

    NASA Astrophysics Data System (ADS)

    Reeves, J.; Braito, V.; Nardini, E.; Matzeu, G.; Lobban, A.; Costa, M.; Pounds, K.; Tombesi, F.; Behar, E.

    2017-10-01

    The recent large XMM-Newton programmes on the nearby quasars PDS 456 and PG 1211+143 have revealed prototype ultra fast outflows in the iron K band through highly blue shifted absorption lines. The wind velocities are in excess of 0.1c and are likely to make a significant contribution to the host galaxy feedback. Here we present evidence for the signature of the fast wind in the soft X-ray band from these luminous quasars, focusing on the spectroscopy with the RGS. In PDS 456, the RGS spectra reveal the presence of soft X-ray broad absorption line profiles, which suggests that PDS 456 is an X-ray equivalent to the BAL quasars, with outflow velocities reaching 0.2c. In PG 1211, the soft X-ray RGS spectra show a complex of several highly blue shifted absorption lines over a wide range of ionisation and reveal outflowing components with velocities between 0.06-0.17c. For both quasars, the soft X-ray absorption is highly variable, even on timescales of days and is most prominent when the quasar flux is low. Overall the results imply the presence of a soft X-ray component of the ultra fast outflows, which we attribute to a clumpy or inhomogeneous phase of the disk wind.

  10. HAPPY BIRTHDAY SWIFT: ULTRA-LONG GRB 141121A AND ITS BROADBAND AFTERGLOW

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cucchiara, A.; Veres, P.; Corsi, A.

    2015-10-20

    We present our extensive observational campaign on the Swift-discovered GRB 141121A, almost 10 years after its launch. Our observations cover radio through X-rays and extend for more than 30 days after discovery. The prompt phase of GRB 141121A lasted 1410 s and, at the derived redshift of z = 1.469, the isotropic energy is E{sub γ,iso} = 8.0 × 10{sup 52} erg. Due to the long prompt duration, GRB 141121A falls into the recently discovered class of ultra-long GRBs (UL-GRBs). Peculiar features of this burst are (1) a flat early-time optical light curve and (2) a radio-to-X-ray rebrightening around threemore » days after the burst. The latter is followed by a steep optical-to-X-ray decay and a much shallower radio fading. We analyze GRB 141121A in the context of the standard forward–reverse shock (FS, RS) scenario and we disentangle the FS and RS contributions. Finally, we comment on the puzzling early-time (t ≲ 3 days) behavior of GRB 141121A, and suggest that its interpretation may require a two-component jet model. Overall, our analysis confirms that the class of UL-GRBs represents our best opportunity to firmly establish the prominent emission mechanisms in action during powerful gamma-ray burst explosions, and future missions (like SVOM, XTiDE, or ISS-Lobster) will provide many more of such objects.« less

  11. Ultra-fast electron capture by electrosterically-stabilized gold nanoparticles.

    PubMed

    Ghandi, Khashayar; Findlater, Alexander D; Mahimwalla, Zahid; MacNeil, Connor S; Awoonor-Williams, Ernest; Zahariev, Federico; Gordon, Mark S

    2015-07-21

    Ultra-fast pre-solvated electron capture has been observed for aqueous solutions of room-temperature ionic liquid (RTIL) surface-stabilized gold nanoparticles (AuNPs; ∼9 nm). The extraordinarily large inverse temperature dependent rate constants (k(e)∼ 5 × 10(14) M(-1) s(-1)) measured for the capture of electrons in solution suggest electron capture by the AuNP surface that is on the timescale of, and therefore in competition with, electron solvation and electron-cation recombination reactions. The observed electron transfer rates challenge the conventional notion that radiation induced biological damage would be enhanced in the presence of AuNPs. On the contrary, AuNPs stabilized by non-covalently bonded ligands demonstrate the potential to quench radiation-induced electrons, indicating potential applications in fields ranging from radiation therapy to heterogeneous catalysis.

  12. Ultra-Slow Dielectric Relaxation Process in Polyols

    NASA Astrophysics Data System (ADS)

    Yomogida, Yoshiki; Minoguchi, Ayumi; Nozaki, Ryusuke

    2004-04-01

    Dielectric relaxation processes with relaxation times larger than that for the structural α process are reported for glycerol, xylitol, sorbitol and their mixtures for the first time. Appearance of this ultra-slow process depends on cooling rate. More rapid cooling gives larger dielectric relaxation strength. However, relaxation time is not affected by cooling rate and shows non-Arrhenius temperature dependence with correlation to the α process. It can be considered that non-equilibrium dynamic structure causes the ultra-slow process. Scale of such structure would be much larger than that of the region for the cooperative molecular orientations for the α process.

  13. Time scale bridging in atomistic simulation of slow dynamics: viscous relaxation and defect activation

    NASA Astrophysics Data System (ADS)

    Kushima, A.; Eapen, J.; Li, Ju; Yip, S.; Zhu, T.

    2011-08-01

    Atomistic simulation methods are known for timescale limitations in resolving slow dynamical processes. Two well-known scenarios of slow dynamics are viscous relaxation in supercooled liquids and creep deformation in stressed solids. In both phenomena the challenge to theory and simulation is to sample the transition state pathways efficiently and follow the dynamical processes on long timescales. We present a perspective based on the biased molecular simulation methods such as metadynamics, autonomous basin climbing (ABC), strain-boost and adaptive boost simulations. Such algorithms can enable an atomic-level explanation of the temperature variation of the shear viscosity of glassy liquids, and the relaxation behavior in solids undergoing creep deformation. By discussing the dynamics of slow relaxation in two quite different areas of condensed matter science, we hope to draw attention to other complex problems where anthropological or geological-scale time behavior can be simulated at atomic resolution and understood in terms of micro-scale processes of molecular rearrangements and collective interactions. As examples of a class of phenomena that can be broadly classified as materials ageing, we point to stress corrosion cracking and cement setting as opportunities for atomistic modeling and simulations.

  14. LIDT-DD: A New Self-Consistent Debris Disc Model Including Radiation Pressure and Coupling Dynamical and Collisional Evolution

    NASA Astrophysics Data System (ADS)

    Kral, Q.; Thebault, P.; Charnoz, S.

    2014-01-01

    The first attempt at developing a fully self-consistent code coupling dynamics and collisions to study debris discs (Kral et al. 2013) is presented. So far, these two crucial mechanisms were studied separately, with N-body and statistical collisional codes respectively, because of stringent computational constraints. We present a new model named LIDT-DD which is able to follow over long timescales the coupled evolution of dynamics (including radiation forces) and collisions in a self-consistent way.

  15. An ultra-low-power filtering technique for biomedical applications.

    PubMed

    Zhang, Tan-Tan; Mak, Pui-In; Vai, Mang-I; Mak, Peng-Un; Wan, Feng; Martins, R P

    2011-01-01

    This paper describes an ultra-low-power filtering technique for biomedical applications designated as T-wave sensing in heart-activities detection systems. The topology is based on a source-follower-based Biquad operating in the sub-threshold region. With the intrinsic advantages of simplicity and high linearity of the source-follower, ultra-low-cutoff filtering can be achieved, simultaneously with ultra low power and good linearity. An 8(th)-order 2.4-Hz lowpass filter design example optimized in a 0.35-μm CMOS process was designed achieving over 85-dB dynamic range, 74-dB stopband attenuation and consuming only 0.36 nW at a 3-V supply.

  16. Explaining the apparent impenetrable barrier to ultra-relativistic electrons in the outer Van Allen belt.

    PubMed

    Ozeke, Louis G; Mann, Ian R; Murphy, Kyle R; Degeling, Alex W; Claudepierre, Seth G; Spence, Harlan E

    2018-05-10

    Recent observations have shown the existence of an apparent impenetrable barrier at the inner edge of the ultra-relativistic outer electron radiation belt. This apparent impenetrable barrier has not been explained. However, recent studies have suggested that fast loss, such as associated with scattering into the atmosphere from man-made very-low frequency transmissions, is required to limit the Earthward extent of the belt. Here we show that the steep flux gradient at the implied barrier location is instead explained as a natural consequence of ultra-low frequency wave radial diffusion. Contrary to earlier claims, sharp boundaries in fast loss processes at the barrier are not needed. Moreover, we show that penetration to the barrier can occur on the timescale of days rather than years as previously reported, with the Earthward extent of the belt being limited by the finite duration of strong solar wind driving, which can encompass only a single geomagnetic storm.

  17. How Kinetics within the Unfolded State Affects Protein Folding: an Analysis Based on Markov State Models and an Ultra-Long MD Trajectory

    PubMed Central

    Deng, Nan-jie; Dai, Wei

    2013-01-01

    Understanding how kinetics in the unfolded state affects protein folding is a fundamentally important yet less well-understood issue. Here we employ three different models to analyze the unfolded landscape and folding kinetics of the miniprotein Trp-cage. The first is a 208 μs explicit solvent molecular dynamics (MD) simulation from D. E. Shaw Research containing tens of folding events. The second is a Markov state model (MSM-MD) constructed from the same ultra-long MD simulation; MSM-MD can be used to generate thousands of folding events. The third is a Markov state model built from temperature replica exchange MD simulations in implicit solvent (MSM-REMD). All the models exhibit multiple folding pathways, and there is a good correspondence between the folding pathways from direct MD and those computed from the MSMs. The unfolded populations interconvert rapidly between extended and collapsed conformations on time scales ≤ 40 ns, compared with the folding time of ≈ 5 μs. The folding rates are independent of where the folding is initiated from within the unfolded ensemble. About 90 % of the unfolded states are sampled within the first 40 μs of the ultra-long MD trajectory, which on average explores ~27 % of the unfolded state ensemble between consecutive folding events. We clustered the folding pathways according to structural similarity into “tubes”, and kinetically partitioned the unfolded state into populations that fold along different tubes. From our analysis of the simulations and a simple kinetic model, we find that when the mixing within the unfolded state is comparable to or faster than folding, the folding waiting times for all the folding tubes are similar and the folding kinetics is essentially single exponential despite the presence of heterogeneous folding paths with non-uniform barriers. When the mixing is much slower than folding, different unfolded populations fold independently leading to non-exponential kinetics. A kinetic partition of

  18. Tree imbalance causes a bias in phylogenetic estimation of evolutionary timescales using heterochronous sequences.

    PubMed

    Duchêne, David; Duchêne, Sebastian; Ho, Simon Y W

    2015-07-01

    Phylogenetic estimation of evolutionary timescales has become routine in biology, forming the basis of a wide range of evolutionary and ecological studies. However, there are various sources of bias that can affect these estimates. We investigated whether tree imbalance, a property that is commonly observed in phylogenetic trees, can lead to reduced accuracy or precision of phylogenetic timescale estimates. We analysed simulated data sets with calibrations at internal nodes and at the tips, taking into consideration different calibration schemes and levels of tree imbalance. We also investigated the effect of tree imbalance on two empirical data sets: mitogenomes from primates and serial samples of the African swine fever virus. In analyses calibrated using dated, heterochronous tips, we found that tree imbalance had a detrimental impact on precision and produced a bias in which the overall timescale was underestimated. A pronounced effect was observed in analyses with shallow calibrations. The greatest decreases in accuracy usually occurred in the age estimates for medium and deep nodes of the tree. In contrast, analyses calibrated at internal nodes did not display a reduction in estimation accuracy or precision due to tree imbalance. Our results suggest that molecular-clock analyses can be improved by increasing taxon sampling, with the specific aims of including deeper calibrations, breaking up long branches and reducing tree imbalance. © 2014 John Wiley & Sons Ltd.

  19. Ultra-low dose (+)-naloxone restores the thermal threshold of morphine tolerant rats.

    PubMed

    Chou, Kuang-Yi; Tsai, Ru-Yin; Tsai, Wei-Yuan; Wu, Ching-Tang; Yeh, Chun-Chang; Cherng, Chen-Hwan; Wong, Chih-Shung

    2013-12-01

    As known, long-term morphine infusion leads to tolerance. We previously demonstrated that both co-infusion and post-administration of ultra-low dose (±)-naloxone restores the antinociceptive effect of morphine in morphine-tolerant rats. However, whether the mechanism of the action of ultra-low dose (±)-naloxone is through opioid receptors or not. Therefore, in the present study, we further investigated the effect of ultra-low dose (+)-naloxone, it does not bind to opioid receptors, on the antinociceptive effect of morphine. Male Wistar rats were implanted with one or two intrathecal (i.t.) catheters; one catheter was connected to a mini-osmotic pump, used for morphine (15 μg/h), ultra-low dose (+)-naloxone (15 pg/h), morphine plus ultra-low dose (+)-naloxone (15 pg/h) or saline (1 μl/h) infusion for 5 days. On day 5, either ultra-low dose (+)-naloxone (15 pg) or saline (5 μl) was injected via the other catheter immediately after discontinued morphine or saline infusion. Three hours later, morphine (15 μg in 5 μl saline) or saline were given intrathecally. All rats received nociceptive tail-flick test every 30 minutes for 120 minutes after morphine challenge at different temperature (45-52°C, respective). Our results showed that, both co-infusion and post-treatment of ultra-low dose (+)-naloxone with morphine preserves the antinociceptive effect of morphine. Moreover, in the post administration rats, ultra-low dose (+)-naloxone further enhances the antinociceptive effect of morphine. This study provides an evidence for ultra-low dose (+)-naloxone as a therapeutic adjuvant for patients who need long-term opioid administration for pain management. Copyright © 2013. Published by Elsevier B.V.

  20. The Physical Origin of Long Gas Depletion Times in Galaxies

    NASA Astrophysics Data System (ADS)

    Semenov, Vadim A.; Kravtsov, Andrey V.; Gnedin, Nickolay Y.

    2017-08-01

    We present a model that explains why galaxies form stars on a timescale significantly longer than the timescales of processes governing the evolution of interstellar gas. We show that gas evolves from a non-star-forming to a star-forming state on a relatively short timescale, and thus the rate of this evolution does not limit the star formation rate (SFR). Instead, the SFR is limited because only a small fraction of star-forming gas is converted into stars before star-forming regions are dispersed by feedback and dynamical processes. Thus, gas cycles into and out of a star-forming state multiple times, which results in a long timescale on which galaxies convert gas into stars. Our model does not rely on the assumption of equilibrium and can be used to interpret trends of depletion times with the properties of observed galaxies and the parameters of star formation and feedback recipes in simulations. In particular, the model explains how feedback self-regulates the SFR in simulations and makes it insensitive to the local star formation efficiency. We illustrate our model using the results of an isolated L *-sized galaxy simulation that reproduces the observed Kennicutt-Schmidt relation for both molecular and atomic gas. Interestingly, the relation for molecular gas is almost linear on kiloparsec scales, although a nonlinear relation is adopted in simulation cells. We discuss how a linear relation emerges from non-self-similar scaling of the gas density PDF with the average gas surface density.

  1. The timescales of global surface-ocean connectivity

    PubMed Central

    Jönsson, Bror F.; Watson, James R.

    2016-01-01

    Planktonic communities are shaped through a balance of local evolutionary adaptation and ecological succession driven in large part by migration. The timescales over which these processes operate are still largely unresolved. Here we use Lagrangian particle tracking and network theory to quantify the timescale over which surface currents connect different regions of the global ocean. We find that the fastest path between two patches—each randomly located anywhere in the surface ocean—is, on average, less than a decade. These results suggest that marine planktonic communities may keep pace with climate change—increasing temperatures, ocean acidification and changes in stratification over decadal timescales—through the advection of resilient types. PMID:27093522

  2. Disturbance Dynamics and Ecological Response: The Contribution of Long-Term Ecological Research.

    Treesearch

    MONICA G. TURNER; SCOTT L. COLLINS; ARIEL L. LUGO; JOHN J. MAGNUSON; T. SCOTT RUPP; FREDERICK J. SWANSON

    2003-01-01

    Long-term ecological research is particularly valuable for understanding disturbance dynamics over long time periods and placing those dynamics in a regional context.We highlighted three case studies from Long Term Ecological Research (LTER) Network sites that have contributed to understanding the causes and consequences of disturbance in ecological systems. The LTER...

  3. Magnetars in Ultra-Long Gamma-Ray Bursts and GRB 111209A

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gompertz, B.; Fruchter, A., E-mail: bgompertz@stsci.edu

    2017-04-10

    Supernova 2011kl, associated with the ultra-long gamma-ray burst (ULGRB) 111209A, exhibited a higher-than-normal peak luminosity, placing it in the parameter space between regular supernovae and super-luminous supernovae. Its light curve can only be matched by an abnormally high fraction of {sup 56}Ni that appears inconsistent with the observed spectrum, and as a result it has been suggested that the supernova, and by extension the gamma-ray burst, are powered by the spin-down of a highly magnetized millisecond pulsar, known as a magnetar. We investigate the broadband observations of ULGRB 111209A and find two independent measures that suggest a high density circumburstmore » environment. However, the light curve of the GRB afterglow shows no evidence of a jet break (the steep decline that would be expected as the jet slows due to the resistance of the external medium) out to three weeks after trigger, implying a wide jet. Combined with the high isotropic energy of the burst, this implies that only a magnetar with a spin period of ∼1 ms or faster can provide enough energy to power both ULGRB 111209A and Supernova 2011kl.« less

  4. The importance of terrestrial weathering for climate system modelling on extended timescales: a study with the UVic ESCM

    NASA Astrophysics Data System (ADS)

    Brault, Marc-Olivier; Matthews, Damon; Mysak, Lawrence

    2016-04-01

    The chemical erosion of carbonate and silicate rocks is a key process in the global carbon cycle and, through its coupling with calcium carbonate deposition in the ocean, is the primary sink of carbon on geologic timescales. The dynamic interdependence of terrestrial weathering rates with atmospheric temperature and carbon dioxide concentrations is crucial to the regulation of Earth's climate over multi-millennial timescales. However any attempts to develop a modeling context for terrestrial weathering as part of a dynamic climate system are limited, mostly because of the difficulty in adapting the multi-millennial timescales of the implied negative feedback mechanism with those of the atmosphere and ocean. Much of the earlier work on this topic is therefore based on box-model approaches, abandoning spatial variability for the sake of computational efficiency and the possibility to investigate the impact of weathering on climate change over time frames much longer than those allowed by traditional climate system models. As a result we still have but a rudimentary understanding of the chemical weathering feedback mechanism and its effects on ocean biogeochemistry and atmospheric CO2. Here, we introduce a spatially-explicit, rock weathering model into the University of Victoria Earth System Climate Model (UVic ESCM). We use a land map which takes into account a number of different rock lithologies, changes in sea level, as well as an empirical model of the temperature and NPP dependency of weathering rates for the different rock types. We apply this new model to the last deglacial period (c. 21000BP to 13000BP) as well as a future climate change scenario (c. 1800AD to 6000AD+), comparing the results of our 2-D version of the weathering feedback mechanism to simulations using only the box-model parameterizations of Meissner et al. [2012]. These simulations reveal the importance of two-dimensional factors (i.e., changes in sea level and rock type distribution) in the

  5. Carbon recycling in deltaic sediments: variations at different timescales in the Rhone River delta

    NASA Astrophysics Data System (ADS)

    Rabouille, C.; Rassmann, J.; Toussaint, F.; Cathalot, C.; Tisnerat-Laborde, N.; Lansard, B.

    2016-02-01

    Terrestrial aquatic environments and the land-sea connection are a major contributors to the Earth carbon cycle, as these act as a source to the atmosphere of about 1 Gt/yr for rivers and up to 0.4 Gt/yr for estuarine/detaic systems. These estimates are largely uncertain because of the large temporal variability of these systems. In estuarine and deltaic sediments, variability combines hydrological variation from the river (floods and drought) and the hydrology of the coastal seas (storms, current surge, wind induced circulation, upwelling) wich are both influencial on biogeochemistry. This hydrological variability interacts with the seasonal variation of in situ production and with thermal activation of bacterial recycling due to seasonal warming of shallow waters. The combination of these processes gives rise to a range of timescales: typically hours to days for resuspension during storms to interannual variations for particulate discharge modulations. Using in situ oxygen microprofiling devices, we have collected a new dataset on organic matter recycling in the Rhone delta and shelf sediments (Northwestern Mediterranean Sea) which covers a wide range of timescales: from hours to a decade. The hourly variation is collected using a new benthic station deployed on the sediments and specially adapted to monitor short-term variations of sediment oxygen micro-profiles during flood or storms. The seasonal to decadal timescale is constituted by a set of oxygen micro-profiles measured on an array of stations in the Rhône prodelta and shelf by an in situ microprofiler during seasonal cruises over 10 year. The results show that Diffusive Oxygen Fluxes which are related to organic matter recycling vary at all timescales, driven mostly by deposition of river material during floods. Resuspension during storms plays a role over short time scales, and its long-term effect could raise the overall oxygen demand of the sediment by 20-30%.

  6. Nanocluster building blocks of artificial square spin ice: Stray-field studies of thermal dynamics

    NASA Astrophysics Data System (ADS)

    Pohlit, Merlin; Porrati, Fabrizio; Huth, Michael; Ohno, Yuzo; Ohno, Hideo; Müller, Jens

    2015-05-01

    We present measurements of the thermal dynamics of a Co-based single building block of an artificial square spin ice fabricated by focused electron-beam-induced deposition. We employ micro-Hall magnetometry, an ultra-sensitive tool to study the stray field emanating from magnetic nanostructures, as a new technique to access the dynamical properties during the magnetization reversal of the spin-ice nanocluster. The obtained hysteresis loop exhibits distinct steps, displaying a reduction of their "coercive field" with increasing temperature. Therefore, thermally unstable states could be repetitively prepared by relatively simple temperature and field protocols allowing one to investigate the statistics of their switching behavior within experimentally accessible timescales. For a selected switching event, we find a strong reduction of the so-prepared states' "survival time" with increasing temperature and magnetic field. Besides the possibility to control the lifetime of selected switching events at will, we find evidence for a more complex behavior caused by the special spin ice arrangement of the macrospins, i.e., that the magnetic reversal statistically follows distinct "paths" most likely driven by thermal perturbation.

  7. Bayesian inference of radiation belt loss timescales.

    NASA Astrophysics Data System (ADS)

    Camporeale, E.; Chandorkar, M.

    2017-12-01

    Electron fluxes in the Earth's radiation belts are routinely studied using the classical quasi-linear radial diffusion model. Although this simplified linear equation has proven to be an indispensable tool in understanding the dynamics of the radiation belt, it requires specification of quantities such as the diffusion coefficient and electron loss timescales that are never directly measured. Researchers have so far assumed a-priori parameterisations for radiation belt quantities and derived the best fit using satellite data. The state of the art in this domain lacks a coherent formulation of this problem in a probabilistic framework. We present some recent progress that we have made in performing Bayesian inference of radial diffusion parameters. We achieve this by making extensive use of the theory connecting Gaussian Processes and linear partial differential equations, and performing Markov Chain Monte Carlo sampling of radial diffusion parameters. These results are important for understanding the role and the propagation of uncertainties in radiation belt simulations and, eventually, for providing a probabilistic forecast of energetic electron fluxes in a Space Weather context.

  8. Historical data as a baseline for conservation: reconstructing long-term faunal extinction dynamics in Late Imperial-modern China.

    PubMed

    Turvey, Samuel T; Crees, Jennifer J; Di Fonzo, Martina M I

    2015-08-22

    Extinction events typically represent extended processes of decline that cannot be reconstructed using short-term studies. Long-term archives are necessary to determine past baselines and the extent of human-caused biodiversity change, but the capacity of historical datasets to provide predictive power for conservation must be assessed within a robust analytical framework. Local Chinese gazetteers represent a more than 400-year country-level dataset containing abundant information on past environmental conditions and include extensive records of gibbons, which have a restricted present-day distribution but formerly occurred across much of China. Gibbons show pre-twentieth century range contraction, with significant fragmentation by the mid-eighteenth century and population loss escalating in the late nineteenth century. Isolated gibbon populations persisted for about 40 years before local extinction. Populations persisted for longer at higher elevations, and disappeared earlier from northern and eastern regions, with the biogeography of population loss consistent with the contagion model of range collapse in response to human demographic expansion spreading directionally across China. The long-term Chinese historical record can track extinction events and human interactions with the environment across much longer timescales than are usually addressed in ecology, contributing novel baselines for conservation and an increased understanding of extinction dynamics and species vulnerability or resilience to human pressures. © 2015 The Authors.

  9. Tropical climate changes at millennial and orbital timescales on the Bolivian Altiplano.

    PubMed

    Baker, P A; Rigsby, C A; Seltzer, G O; Fritz, S C; Lowenstein, T K; Bacher, N P; Veliz, C

    2001-02-08

    Tropical South America is one of the three main centres of the global, zonal overturning circulation of the equatorial atmosphere (generally termed the 'Walker' circulation). Although this area plays a key role in global climate cycles, little is known about South American climate history. Here we describe sediment cores and down-hole logging results of deep drilling in the Salar de Uyuni, on the Bolivian Altiplano, located in the tropical Andes. We demonstrate that during the past 50,000 years the Altiplano underwent important changes in effective moisture at both orbital (20,000-year) and millennial timescales. Long-duration wet periods, such as the Last Glacial Maximum--marked in the drill core by continuous deposition of lacustrine sediments--appear to have occurred in phase with summer insolation maxima produced by the Earth's precessional cycle. Short-duration, millennial events correlate well with North Atlantic cold events, including Heinrich events 1 and 2, as well as the Younger Dryas episode. At both millennial and orbital timescales, cold sea surface temperatures in the high-latitude North Atlantic were coeval with wet conditions in tropical South America, suggesting a common forcing.

  10. Advances in time-scale algorithms

    NASA Technical Reports Server (NTRS)

    Stein, S. R.

    1993-01-01

    The term clock is usually used to refer to a device that counts a nearly periodic signal. A group of clocks, called an ensemble, is often used for time keeping in mission critical applications that cannot tolerate loss of time due to the failure of a single clock. The time generated by the ensemble of clocks is called a time scale. The question arises how to combine the times of the individual clocks to form the time scale. One might naively be tempted to suggest the expedient of averaging the times of the individual clocks, but a simple thought experiment demonstrates the inadequacy of this approach. Suppose a time scale is composed of two noiseless clocks having equal and opposite frequencies. The mean time scale has zero frequency. However if either clock fails, the time-scale frequency immediately changes to the frequency of the remaining clock. This performance is generally unacceptable and simple mean time scales are not used. First, previous time-scale developments are reviewed and then some new methods that result in enhanced performance are presented. The historical perspective is based upon several time scales: the AT1 and TA time scales of the National Institute of Standards and Technology (NIST), the A.1(MEAN) time scale of the US Naval observatory (USNO), the TAI time scale of the Bureau International des Poids et Measures (BIPM), and the KAS-1 time scale of the Naval Research laboratory (NRL). The new method was incorporated in the KAS-2 time scale recently developed by Timing Solutions Corporation. The goal is to present time-scale concepts in a nonmathematical form with as few equations as possible. Many other papers and texts discuss the details of the optimal estimation techniques that may be used to implement these concepts.

  11. Variability of fire emissions on interannual to multi-decadal timescales in two Earth System models

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ward, D. S.; Shevliakova, E.; Malyshev, S.

    Connections between wildfires and modes of variability in climate are sought as a means for predicting fire activity on interannual to multi-decadal timescales. Several fire drivers, such as temperature and local drought index, have been shown to vary on these timescales, and analysis of tree-ring data suggests covariance between fires and climate oscillation indices in some regions. HBut, the shortness of the satellite record of global fire events limits investigations on larger spatial scales. Here we explore the interplay between climate variability and wildfire emissions with the preindustrial long control numerical experiments and historical ensembles of CESM1 and the NOAA/GFDLmore » ESM2Mb. We find that interannual variability in fires is underpredicted in both Earth System models (ESMs) compared to present day fire emission inventories. Modeled fire emissions respond to the El Niño/southern oscillation (ENSO) and Pacific decadal oscillation (PDO) with increases in southeast Asia and boreal North America emissions, and decreases in southern North America and Sahel emissions, during the ENSO warm phase in both ESMs, and the PDO warm phase in CESM1. In addition, CESM1 produces decreases in boreal northern hemisphere fire emissions for the warm phase of the Atlantic Meridional Oscillation. Through analysis of the long control simulations, we show that the 20th century trends in both ESMs are statistically significant, meaning that the signal of anthropogenic activity on fire emissions over this time period is detectable above the annual to decadal timescale noise. However, the trends simulated by the two ESMs are of opposite sign (CESM1 decreasing, ESM2Mb increasing), highlighting the need for improved understanding, proxy observations, and modeling to resolve this discrepancy.« less

  12. Variability of fire emissions on interannual to multi-decadal timescales in two Earth System models

    DOE PAGES

    Ward, D. S.; Shevliakova, E.; Malyshev, S.; ...

    2016-12-02

    Connections between wildfires and modes of variability in climate are sought as a means for predicting fire activity on interannual to multi-decadal timescales. Several fire drivers, such as temperature and local drought index, have been shown to vary on these timescales, and analysis of tree-ring data suggests covariance between fires and climate oscillation indices in some regions. HBut, the shortness of the satellite record of global fire events limits investigations on larger spatial scales. Here we explore the interplay between climate variability and wildfire emissions with the preindustrial long control numerical experiments and historical ensembles of CESM1 and the NOAA/GFDLmore » ESM2Mb. We find that interannual variability in fires is underpredicted in both Earth System models (ESMs) compared to present day fire emission inventories. Modeled fire emissions respond to the El Niño/southern oscillation (ENSO) and Pacific decadal oscillation (PDO) with increases in southeast Asia and boreal North America emissions, and decreases in southern North America and Sahel emissions, during the ENSO warm phase in both ESMs, and the PDO warm phase in CESM1. In addition, CESM1 produces decreases in boreal northern hemisphere fire emissions for the warm phase of the Atlantic Meridional Oscillation. Through analysis of the long control simulations, we show that the 20th century trends in both ESMs are statistically significant, meaning that the signal of anthropogenic activity on fire emissions over this time period is detectable above the annual to decadal timescale noise. However, the trends simulated by the two ESMs are of opposite sign (CESM1 decreasing, ESM2Mb increasing), highlighting the need for improved understanding, proxy observations, and modeling to resolve this discrepancy.« less

  13. Lagrangian Timescales of Southern Ocean Upwelling in a Hierarchy of Model Resolutions

    NASA Astrophysics Data System (ADS)

    Drake, Henri F.; Morrison, Adele K.; Griffies, Stephen M.; Sarmiento, Jorge L.; Weijer, Wilbert; Gray, Alison R.

    2018-01-01

    In this paper we study upwelling pathways and timescales of Circumpolar Deep Water (CDW) in a hierarchy of models using a Lagrangian particle tracking method. Lagrangian timescales of CDW upwelling decrease from 87 years to 31 years to 17 years as the ocean resolution is refined from 1° to 0.25° to 0.1°. We attribute some of the differences in timescale to the strength of the eddy fields, as demonstrated by temporally degrading high-resolution model velocity fields. Consistent with the timescale dependence, we find that an average Lagrangian particle completes 3.2 circumpolar loops in the 1° model in comparison to 0.9 loops in the 0.1° model. These differences suggest that advective timescales and thus interbasin merging of upwelling CDW may be overestimated by coarse-resolution models, potentially affecting the skill of centennial scale climate change projections.

  14. Mechanism of transient force augmentation varying with two distinct timescales for interacting vortex rings

    NASA Astrophysics Data System (ADS)

    Fu, Zhidong; Qin, Suyang; Liu, Hong

    2014-01-01

    The dynamics of dual vortex ring flows is studied experimentally and numerically in a model system that consists of a piston-cylinder apparatus. The flows are generated by double identical strokes which have the velocity profile characterized by the sinusoidal function of half the period. By calculating the total wake impulse in two strokes in the experiments, it is found that the average propulsive force increases by 50% in the second stroke for the sufficiently small stroke length, compared with the first stroke. In the numerical simulations, two types of transient force augmentation are revealed, there being the transient force augmentation for the small stroke lengths and the absolute transient force augmentation for the large stroke lengths. The relative transient force augmentation increases to 78% for L/D = 1, while the absolute transient force augmentation for L/D = 4 is twice as much as that for L/D = 1. Further investigation demonstrates that the force augmentation is attributed to the interaction between vortex rings, which induces transport of vortex impulse and more evident fluid entrainment. The critical situation of vortex ring separation is defined and indicated, with vortex spacing falling in a narrow gap when the stroke lengths vary. A new model is proposed concerning the limiting process of impulse, further suggesting that apart from vortex formation timescale, vortex spacing should be interpreted as an independent timescale to reflect the dynamics of vortex interaction.

  15. Intrinsic vs. spurious long-range memory in high-frequency records of environmental radioactivity - Critical re-assessment and application to indoor 222Rn concentrations from Coimbra, Portugal

    NASA Astrophysics Data System (ADS)

    Donner, Reik V.; Potirakis, Stelios M.; Barbosa, Susana M.; Matos, Jose A. O.

    2015-04-01

    The presence or absence of long-range correlations in environmental radioactivity fluctuations has recently attracted considerable interest. Among a multiplicity of practically relevant applications, identifying and disentangling the environmental factors controlling the variable concentrations of the radioactive noble gas Radon is important for estimating its effect on human health and the efficiency of possible measures for reducing the corresponding exposition. In this work, we present a critical re-assessment of a multiplicity of complementary methods that have been previously applied for evaluating the presence of long-range correlations and fractal scaling in environmental Radon variations with a particular focus on the specific properties of the underlying time series. As an illustrative case study, we subsequently re-analyze two high-frequency records of indoor Radon concentrations from Coimbra, Portugal, each of which spans several months of continuous measurements at a high temporal resolution of five minutes. Our results reveal that at the study site, Radon concentrations exhibit complex multi-scale dynamics with qualitatively different properties at different time-scales: (i) essentially white noise in the high-frequency part (up to time-scales of about one hour), (ii) spurious indications of a non-stationary, apparently long-range correlated process (at time scales between hours and one day) arising from marked periodic components probably related to tidal frequencies, and (iii) low-frequency variability indicating a true long-range dependent process, which might be dominated by a response to meteorological drivers. In the presence of such multi-scale variability, common estimators of long-range memory in time series are necessarily prone to fail if applied to the raw data without previous separation of time-scales with qualitatively different dynamics. We emphasize that similar properties can be found in other types of geophysical time series (for

  16. Dancing to CHANGA: a self-consistent prediction for close SMBH pair formation time-scales following galaxy mergers

    NASA Astrophysics Data System (ADS)

    Tremmel, M.; Governato, F.; Volonteri, M.; Quinn, T. R.; Pontzen, A.

    2018-04-01

    We present the first self-consistent prediction for the distribution of formation time-scales for close supermassive black hole (SMBH) pairs following galaxy mergers. Using ROMULUS25, the first large-scale cosmological simulation to accurately track the orbital evolution of SMBHs within their host galaxies down to sub-kpc scales, we predict an average formation rate density of close SMBH pairs of 0.013 cMpc-3 Gyr-1. We find that it is relatively rare for galaxy mergers to result in the formation of close SMBH pairs with sub-kpc separation and those that do form are often the result of Gyr of orbital evolution following the galaxy merger. The likelihood and time-scale to form a close SMBH pair depends strongly on the mass ratio of the merging galaxies, as well as the presence of dense stellar cores. Low stellar mass ratio mergers with galaxies that lack a dense stellar core are more likely to become tidally disrupted and deposit their SMBH at large radii without any stellar core to aid in their orbital decay, resulting in a population of long-lived `wandering' SMBHs. Conversely, SMBHs in galaxies that remain embedded within a stellar core form close pairs in much shorter time-scales on average. This time-scale is a crucial, though often ignored or very simplified, ingredient to models predicting SMBH mergers rates and the connection between SMBH and star formation activity.

  17. Dynamics and morphology of chiral magnetic bubbles in perpendicularly magnetized ultra-thin films

    NASA Astrophysics Data System (ADS)

    Sarma, Bhaskarjyoti; Garcia-Sanchez, Felipe; Nasseri, S. Ali; Casiraghi, Arianna; Durin, Gianfranco

    2018-06-01

    We study bubble domain wall dynamics using micromagnetic simulations in perpendicularly magnetized ultra-thin films with disorder and Dzyaloshinskii-Moriya interaction. Disorder is incorporated into the material as grains with randomly distributed sizes and varying exchange constant at the edges. As expected, magnetic bubbles expand asymmetrically along the axis of the in-plane field under the simultaneous application of out-of-plane and in-plane fields. Remarkably, the shape of the bubble has a ripple-like part which causes a kink-like (steep decrease) feature in the velocity versus in-plane field curve. We show that these ripples originate due to the nucleation and interaction of vertical Bloch lines. Furthermore, we show that the Dzyaloshinskii-Moriya interaction field is not constant but rather depends on the in-plane field. We also extend the collective coordinate model for domain wall motion to a magnetic bubble and compare it with the results of micromagnetic simulations.

  18. Resilient cooperators stabilize long-run cooperation in the finitely repeated Prisoner's Dilemma

    PubMed Central

    Mao, Andrew; Dworkin, Lili; Suri, Siddharth; Watts, Duncan J.

    2017-01-01

    Learning in finitely repeated games of cooperation remains poorly understood in part because their dynamics play out over a timescale exceeding that of traditional lab experiments. Here, we report results of a virtual lab experiment in which 94 subjects play up to 400 ten-round games of Prisoner's Dilemma over the course of twenty consecutive weekdays. Consistent with previous work, the typical round of first defection moves earlier for several days; however, this unravelling process stabilizes after roughly one week. Analysing individual strategies, we find that approximately 40% of players behave as resilient cooperators who avoid unravelling even at significant cost to themselves. Finally, using a standard learning model we predict that a sufficiently large minority of resilient cooperators can permanently stabilize unravelling among a majority of rational players. These results shed hopeful light on the long-term dynamics of cooperation, and demonstrate the importance of long-run experiments. PMID:28082739

  19. The Dependence of Cloud-SST Feedback on Circulation Regime and Timescale

    NASA Astrophysics Data System (ADS)

    Middlemas, E.; Clement, A. C.; Medeiros, B.

    2017-12-01

    Studies suggest cloud radiative feedback amplifies internal variability of Pacific sea surface temperature (SST) on interannual-and-longer timescales, though only a few modeling studies have tested the quantitative importance of this feedback (Bellomo et al. 2014b, Brown et al. 2016, Radel et al. 2016 Burgman et al. 2017). We prescribe clouds from a previous control run in the radiation module in Community Atmospheric Model (CAM5-slab), a method called "cloud-locking". By comparing this run to a control run, in which cloud radiative forcing can feedback on the climate system, we isolate the effect of cloud radiative forcing on SST variability. Cloud-locking prevents clouds from radiatively interacting with atmospheric circulation, water vapor, and SST, while maintaining a similar mean state to the control. On all timescales, cloud radiative forcing's influence on SST variance is modulated by the circulation regime. Cloud radiative forcing amplifies SST variance in subsiding regimes and dampens SST variance in convecting regimes. In this particular model, a tug of war between latent heat flux and cloud radiative forcing determines the variance of SST, and the winner depends on the timescale. On decadal-and-longer timescales, cloud radiative forcing plays a relatively larger role than on interannual-and-shorter timescales, while latent heat flux plays a smaller role. On longer timescales, the absence of cloud radiative feedback changes SST variance in a zonally asymmetric pattern in the Pacific Ocean that resembles an IPO-like pattern. We also present an analysis of cloud feedback's role on Pacific SST variability among preindustrial control CMIP5 models to test the model robustness of our results. Our results suggest that circulation plays a crucial role in cloud-SST feedbacks across the globe and cloud radiative feedbacks cannot be ignored when studying SST variability on decadal-and-longer timescales.

  20. Wind-Friendly Flexible Ramping Product Design in Multi-Timescale Power System Operations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cui, Mingjian; Zhang, Jie; Wu, Hongyu

    With increasing wind power penetration in the electricity grid, system operators are recognizing the need for additional flexibility, and some are implementing new ramping products as a type of ancillary service. However, wind is generally thought of as causing the need for ramping services, not as being a potential source for the service. In this paper, a multi-timescale unit commitment and economic dispatch model is developed to consider the wind power ramping product (WPRP). An optimized swinging door algorithm with dynamic programming is applied to identify and forecast wind power ramps (WPRs). Designed as positive characteristics of WPRs, the WPRPmore » is then integrated into the multi-timescale dispatch model that considers new objective functions, ramping capacity limits, active power limits, and flexible ramping requirements. Numerical simulations on the modified IEEE 118-bus system show the potential effectiveness of WPRP in increasing the economic efficiency of power system operations with high levels of wind power penetration. It is found that WPRP not only reduces the production cost by using less ramping reserves scheduled by conventional generators, but also possibly enhances the reliability of power system operations. Moreover, wind power forecasts play an important role in providing high-quality WPRP service.« less

  1. Rapid advance and retreat over centennial/millennial timescales at Kangiata Nunaata Sermia, SW Greenland - implications for modelling, and behaviour of tidewater glaciers

    NASA Astrophysics Data System (ADS)

    Lea, J.; Mair, D. W.; Rea, B. R.; Schofield, J.; Kamenos, N.; Pearce, D.; Schoenrock, K. M.

    2017-12-01

    While the Greenland Ice Sheet has undergone significant retreat over the last 80 years, our understanding of the ice sheet's response to climate forcing over centennial to millennial timescales is poorly constrained. Knowledge of marine glacier outlets over these timescales would provide crucial information regarding longer term ice sheet dynamics, beyond instrumental and historical records. It is notably difficult to constrain such histories for these glaciers due to: (i) a highly dynamic ice front environment in combination with the Little Ice Age advance(s) destroying much of the preceding evidence for glacier change; (ii) often poor landform/sediment preservation due to steep sided fjords; (iii) the areas with greatest preservation potential, the fjords bottoms, being submarine and often ice choked, and therefore non-trivial to survey, and sample. The tidewater glacier Kangiata Nunaata Sermia (KNS), SW Greenland provides an exception to this. Here we present a record of >22km of terminus advance and retreat spanning the last 1000 years using a combination of geomorphological, sedimentological and archaeological evidence. This timescale includes periods of substantial warming and cooling of air temperatures that appear to correspond to periods of advance and retreat. Results also suggest that the average advance rates in the early part of the millennium (110 m a-1) are of a similar magnitude to contemporary retreat rates observed around Greenland. The results generated here provide an ideal opportunity to validate the performance of numerical models (notably those that include calving) over centennial timescales. Evaluating model performance against the past behaviour of KNS could therefore lead to significant improvements in the confidence of ice sheet change projections up to 2100 and beyond.

  2. Integrating river incision rates over timescales in the Ecuadorian Andes: from uplift history to current erosion rates

    NASA Astrophysics Data System (ADS)

    Campforts, Benjamin; Govers, Gerard; Vanacker, Veerle; Tenorio, Gustavo

    2013-04-01

    River profile development is studied at different timescales, from the response to uplift over millions of years over steady state erosion rates over millennia to the response to a single event, such as a major landslide. At present, few attempts have been made to compare data obtained over various timescales. Therefore we do not know to what extent data and model results are compatible: do long-term river profile development models yield erosion rates that are compatible with information obtained over shorter time spans, both in terms of absolute rates and spatial patterns or not? Such comparisons could provide crucial insights into the nature of river development and allow us to assess the confidence we may have when predicting river response at different timescales (e.g. Kirchner et al., 2001). A major issue hampering such comparison is the uncertainty involved in the calibration of long-term river profile development models. Furthermore, calibration data on different timescales are rarely available for a specific region. In this research, we set up a river profile development model similar to the one used by Roberts & White (2010) and successfully calibrated it for the northern Ecuadorian Andes using detailed uplift and sedimentological data. Subsequently we used the calibrated model to simulate river profile development in the southern Ecuadorian Andes. The calibrated model allows to reconstruct the Andean uplift history in southern Ecuador, which is characterized by a very strong uplift phase during the last 5 My. Erosion rates derived from the modeled river incision rates were then compared with 10Be derived basin-wide erosion rates for a series of basins within the study area. We found that the model-inferred erosion rates for the last millennia are broadly compatible with the cosmogenic derived denudation rates, both in terms of absolute erosion rates as well as in terms of their spatial distribution. Hence, a relatively simple river profile development

  3. Dynamic Measurement of Extra Long Stroke Cylinder in the Pneumatic System

    NASA Astrophysics Data System (ADS)

    Chang, Ho; Lan, Chou-wei; Chen, Liang-Chia

    2006-10-01

    This paper sets up the measure and control system of the dynamic characteristics of the extra long stroke cylinder. In the different types of the control conditions (e.g. different control law, operating pressure and direct control valves), using the measure and control system to measure the relation between the pressure and the velocity of the motion of the long stroke cylinder and to observe the stick slip phenomenon of the motion of the long stroke cylinder. In the innovate measurement system, two pressure sensors are set on the long stroke cylinder to measure the difference of the pressure between the inlet and the exhaust of the long stroke cylinder. In additions, a draw line encoder is set on the system to measure the position and the velocity of the motion of the long stroke cylinder. The measuring data of the measure system is transferred to the computer via A/D interface card and counter card, and Home-made program of Haptic Interface Device is used to control the system, saving the data of the motion of the long stroke cylinder. The system uses different types of direction control valve to control the motion of the long stroke cylinder and compares the difference of the motion of the long stroke cylinder. The results show that the motion of the cylinder that pauses in the middle of the cylinder stroke and causes the stick slip phenomenon is more violent than the stick slip phenomenon in other position. When the length of the pause time reaches the some range, the acceleration of the motion of the cylinder will be rised substantially. This paper not only focuses on the testing method of the dynamic characteristics of the motion of the long stroke cylinder, but also includes the analysis of the dynamic characteristics of the motion of the long stroke cylinder. It provides the data of the dynamic characteristics of the motion of the long stroke cylinder to improve and design the pneumatic system of the long stroke cylinder.

  4. Taking care of business in a flash: constraining the time-scale for low-mass satellite quenching with ELVIS

    NASA Astrophysics Data System (ADS)

    Fillingham, Sean P.; Cooper, Michael C.; Wheeler, Coral; Garrison-Kimmel, Shea; Boylan-Kolchin, Michael; Bullock, James S.

    2015-12-01

    The vast majority of dwarf satellites orbiting the Milky Way and M31 are quenched, while comparable galaxies in the field are gas rich and star forming. Assuming that this dichotomy is driven by environmental quenching, we use the Exploring the Local Volume in Simulations (ELVIS) suite of N-body simulations to constrain the characteristic time-scale upon which satellites must quench following infall into the virial volumes of their hosts. The high satellite quenched fraction observed in the Local Group demands an extremely short quenching time-scale (˜2 Gyr) for dwarf satellites in the mass range M⋆ ˜ 106-108 M⊙. This quenching time-scale is significantly shorter than that required to explain the quenched fraction of more massive satellites (˜8 Gyr), both in the Local Group and in more massive host haloes, suggesting a dramatic change in the dominant satellite quenching mechanism at M⋆ ≲ 108 M⊙. Combining our work with the results of complementary analyses in the literature, we conclude that the suppression of star formation in massive satellites (M⋆ ˜ 108-1011 M⊙) is broadly consistent with being driven by starvation, such that the satellite quenching time-scale corresponds to the cold gas depletion time. Below a critical stellar mass scale of ˜108 M⊙, however, the required quenching times are much shorter than the expected cold gas depletion times. Instead, quenching must act on a time-scale comparable to the dynamical time of the host halo. We posit that ram-pressure stripping can naturally explain this behaviour, with the critical mass (of M⋆ ˜ 108 M⊙) corresponding to haloes with gravitational restoring forces that are too weak to overcome the drag force encountered when moving through an extended, hot circumgalactic medium.

  5. Ultra-low power high-dynamic range color pixel embedding RGB to r-g chromaticity transformation

    NASA Astrophysics Data System (ADS)

    Lecca, Michela; Gasparini, Leonardo; Gottardi, Massimo

    2014-05-01

    This work describes a novel color pixel topology that converts the three chromatic components from the standard RGB space into the normalized r-g chromaticity space. This conversion is implemented with high-dynamic range and with no dc power consumption, and the auto-exposure capability of the sensor ensures to capture a high quality chromatic signal, even in presence of very bright illuminants or in the darkness. The pixel is intended to become the basic building block of a CMOS color vision sensor, targeted to ultra-low power applications for mobile devices, such as human machine interfaces, gesture recognition, face detection. The experiments show that significant improvements of the proposed pixel with respect to standard cameras in terms of energy saving and accuracy on data acquisition. An application to skin color-based description is presented.

  6. Cued Memory Retrieval Exhibits Reinstatement of High Gamma Power on a Faster Timescale in the Left Temporal Lobe and Prefrontal Cortex.

    PubMed

    Yaffe, Robert B; Shaikhouni, Ammar; Arai, Jennifer; Inati, Sara K; Zaghloul, Kareem A

    2017-04-26

    Converging evidence suggests that reinstatement of neural activity underlies our ability to successfully retrieve memories. However, the temporal dynamics of reinstatement in the human cortex remain poorly understood. One possibility is that neural activity during memory retrieval, like replay of spiking neurons in the hippocampus, occurs at a faster timescale than during encoding. We tested this hypothesis in 34 participants who performed a verbal episodic memory task while we recorded high gamma (62-100 Hz) activity from subdural electrodes implanted for seizure monitoring. We show that reinstatement of distributed patterns of high gamma activity occurs faster than during encoding. Using a time-warping algorithm, we quantify the timescale of the reinstatement and identify brain regions that show significant timescale differences between encoding and retrieval. Our data suggest that temporally compressed reinstatement of cortical activity is a feature of cued memory retrieval. SIGNIFICANCE STATEMENT We show that cued memory retrieval reinstates neural activity on a faster timescale than was present during encoding. Our data therefore provide a link between reinstatement of neural activity in the cortex and spontaneous replay of cortical and hippocampal spiking activity, which also exhibits temporal compression, and suggest that temporal compression may be a universal feature of memory retrieval. Copyright © 2017 the authors 0270-6474/17/374472-09$15.00/0.

  7. Cued Memory Retrieval Exhibits Reinstatement of High Gamma Power on a Faster Timescale in the Left Temporal Lobe and Prefrontal Cortex

    PubMed Central

    Shaikhouni, Ammar

    2017-01-01

    Converging evidence suggests that reinstatement of neural activity underlies our ability to successfully retrieve memories. However, the temporal dynamics of reinstatement in the human cortex remain poorly understood. One possibility is that neural activity during memory retrieval, like replay of spiking neurons in the hippocampus, occurs at a faster timescale than during encoding. We tested this hypothesis in 34 participants who performed a verbal episodic memory task while we recorded high gamma (62–100 Hz) activity from subdural electrodes implanted for seizure monitoring. We show that reinstatement of distributed patterns of high gamma activity occurs faster than during encoding. Using a time-warping algorithm, we quantify the timescale of the reinstatement and identify brain regions that show significant timescale differences between encoding and retrieval. Our data suggest that temporally compressed reinstatement of cortical activity is a feature of cued memory retrieval. SIGNIFICANCE STATEMENT We show that cued memory retrieval reinstates neural activity on a faster timescale than was present during encoding. Our data therefore provide a link between reinstatement of neural activity in the cortex and spontaneous replay of cortical and hippocampal spiking activity, which also exhibits temporal compression, and suggest that temporal compression may be a universal feature of memory retrieval. PMID:28336569

  8. Rhabdomyolysis and exercise-associated hyponatremia in ultra-bikers and ultra-runners.

    PubMed

    Chlíbková, Daniela; Knechtle, Beat; Rosemann, Thomas; Tomášková, Ivana; Novotný, Jan; Žákovská, Alena; Uher, Tomáš

    2015-01-01

    Exercise-associated hyponatremia (EAH), rhabdomyolysis and renal failure appear to be a unique problem in ultra-endurance racers. We investigated the combined occurrence of EAH and rhabdomyolysis in seven different ultra-endurance races and disciplines (i.e. multi-stage mountain biking, 24-h mountain biking, 24-h ultra-running and 100-km ultra-running). Two (15.4%) ultra-runners (man and woman) from hyponatremic ultra-athletes (n = 13) and four (4%) ultra-runners (four men) from the normonatremic group (n = 100) showed rhabdomyolysis following elevated blood creatine kinase (CK) levels > 10,000 U/L without the development of renal failure and the necessity of a medical treatment. Post-race creatine kinase, plasma and urine creatinine significantly increased, while plasma [Na(+)] and creatine clearance decreased in hyponatremic and normonatremic athletes, respectively. The percentage increase of CK was higher in the hyponatremic compared to the normonatremic group (P < 0.05). Post-race CK levels were higher in ultra-runners compared to mountain bikers (P < 0.01), in faster normonatremic (P < 0.05) and older and more experienced hyponatremic ultra-athletes (P < 0.05). In all finishers, pre-race plasma [K(+)] was related to post-race CK (P < 0.05). Hyponatremic ultra-athletes tended to develop exercise-induced rhabdomyolysis more frequently than normonatremic ultra-athletes. Ultra-runners tended to develop rhabdomyolysis more frequently than mountain bikers. We found no association between post-race plasma [Na(+)] and CK concentration in both hypo- and normonatremic ultra-athletes.

  9. The Timescale-dependent Color Variability of Quasars Viewed with /GALEX

    NASA Astrophysics Data System (ADS)

    Zhu, Fei-Fan; Wang, Jun-Xian; Cai, Zhen-Yi; Sun, Yu-Han

    2016-11-01

    In a recent work by Sun et al., the color variation of quasars, namely the bluer-when-brighter trend, was found to be timescale dependent using the SDSS g/r band light curves in Stripe 82. Such timescale dependence, I.e., bluer variation at shorter timescales, supports the thermal fluctuation origin of the UV/optical variation in quasars, and can be modeled well with the inhomogeneous accretion disk model. In this paper, we extend the study to much shorter wavelengths in the rest frame (down to extreme UV) using GALaxy Evolution eXplorer (GALEX) photometric data of quasars collected in two ultraviolet bands (near-UV and far-UV). We develop Monte Carlo simulations to correct for possible biases due to the considerably larger photometric uncertainties in the GALEX light curves (particularly in the far-UV, compared with the SDSS g/r bands), which otherwise could produce artificial results. We securely confirm the previously discovered timescale dependence of the color variability with independent data sets and at shorter wavelengths. We further find that the slope of the correlation between the amplitude of the color variation and timescale appears even steeper than predicted by the inhomogeneous disk model, which assumes that disk fluctuations follow a damped random walk (DRW) process. The much flatter structure function observed in the far-UV compared with that at longer wavelengths implies deviation from the DRW process in the inner disk, where rest-frame extreme UV radiation is produced.

  10. Study on creep of fiber reinforced ultra-high strength concrete based on strength

    NASA Astrophysics Data System (ADS)

    Peng, Wenjun; Wang, Tao

    2018-04-01

    To complement the creep performance of ultra-high strength concrete, the long creep process of fiber reinforced concrete was studied in this paper. The long-term creep process and regularity of ultra-high strength concrete with 0.5% PVA fiber under the same axial compression were analyzed by using concrete strength (C80/C100/C120) as a variable. The results show that the creep coefficient of ultra-high strength concrete decreases with the increase of concrete strength. Compared with ACI209R (92), GL2000 models, it is found that the predicted value of ACI209R (92) are close to the experimental value, and the creep prediction model suitable for this experiment is proposed based on ACI209R (92).

  11. Constitutive modeling and dynamic softening mechanism during hot deformation of an ultra-pure 17%Cr ferritic stainless steel stabilized with Nb

    NASA Astrophysics Data System (ADS)

    Gao, Fei; Liu, Zhenyu; Misra, R. D. K.; Liu, Haitao; Yu, Fuxiao

    2014-09-01

    The hot deformation behavior of an ultra-pure 17%Cr ferritic stainless steel was studied in the temperature range of 750-1000 °C and strain rates of 0.5 to 10 s-1 using isothermal hot compression tests in a thermomechanical simulator. The microstructural evolution was investigated using electron backscattered diffraction and transmission electron microscopy. A modified constitutive equation considering the effect of strain on material constant was developed, which predicted the flow stress for the deformation conditions studied, except at 950 °C in 1 s-1 and 900 °C in 10 s-1. Decreasing deformation temperature and increasing strain was beneficial in refining the microstructure. Decreasing deformation temperature, the in-grain shear bands appeared in the microstructure. It is suggested that the dynamic softening mechanism is closely related to deformation temperature. At low deformation temperature, dynamic recovery was major softening mechanism and no dynamic recrystallization occurred. At high deformation temperature, dynamic softening was explained in terms of efficient dynamic recovery and limited continuous dynamic recrystallization. A drop in the flow stress was not found due to very small fraction of new grains nucleated during dynamic recrystallization.

  12. Variability of the Tropical Ocean Surface Temperatures at Decadal-Multidecadal Timescales. Part I: The Atlantic Ocean.

    NASA Astrophysics Data System (ADS)

    Mehta, Vikram M.

    1998-09-01

    Gridded time series from the Global Ocean Surface Temperature Atlas were analyzed with a variety of techniques to identify spatial structures and oscillation periods of the tropical Atlantic sea surface temperature (SST) variations at decadal timescales, and to develop physical interpretations of statistical patterns of decadal SST variations. Each time series was 110 yr (1882-1991) long. The tropical Atlantic SST variations were compared with decadal variations in a 74-yr-long (1912-85) north Nordeste Brazil rainfall time series and a 106-yr-long (1886-1991) tropical Atlantic cyclone activity index time series. The tropical Atlantic SST variations were also compared with decadal variations in the extratropical Atlantic SST.Multiyear to multidecadal variations in the cross-equatorial dipole pattern identified as a dominant empirical pattern of the tropical Atlantic SST variations in earlier and present studies are shown to be variations in the approximately north-south gradient of SST anomalies. It is also shown that there was no dynamical-thermodynamical, dipole mode of SST variations during the analysis period. There was a distinct decadal timescale (12-13 yr) of SST variations in the tropical South Atlantic, whereas no distinct decadal timescale was found in the tropical North Atlantic SST variations. Approximately 80% of the coherent decadal variance in the cross-equatorial SST gradient was `explained' by coherent decadal oscillations in the tropical South Atlantic SSTs. There were three, possibly physical, modes of decadal variations in the tropical Atlantic SSTs during the analysis period. In the more energetic mode of the North Atlantic decadal SST variations, anomalies traveled into the tropical North Atlantic from the extratropical North Atlantic along the eastern boundary of the basin. The anomalies strengthened and resided in the tropical North Atlantic for several years, then frequently traveled northward into the mid-high-latitude North Atlantic along

  13. Neuronal oscillations on an ultra-slow timescale: daily rhythms in electrical activity and gene expression in the mammalian master circadian clockwork.

    PubMed

    Belle, Mino D C; Diekman, Casey O

    2018-02-03

    Neuronal oscillations of the brain, such as those observed in the cortices and hippocampi of behaving animals and humans, span across wide frequency bands, from slow delta waves (0.1 Hz) to ultra-fast ripples (600 Hz). Here, we focus on ultra-slow neuronal oscillators in the hypothalamic suprachiasmatic nuclei (SCN), the master daily clock that operates on interlocking transcription-translation feedback loops to produce circadian rhythms in clock gene expression with a period of near 24 h (< 0.001 Hz). This intracellular molecular clock interacts with the cell's membrane through poorly understood mechanisms to drive the daily pattern in the electrical excitability of SCN neurons, exhibiting an up-state during the day and a down-state at night. In turn, the membrane activity feeds back to regulate the oscillatory activity of clock gene programs. In this review, we emphasise the circadian processes that drive daily electrical oscillations in SCN neurons, and highlight how mathematical modelling contributes to our increasing understanding of circadian rhythm generation, synchronisation and communication within this hypothalamic region and across other brain circuits. © 2018 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  14. Heterogeneous chain dynamics and aggregate lifetimes in precise acid-containing polyethylenes: Experiments and simulations

    DOE PAGES

    Middleton, L. Robert; Tarver, Jacob D.; Cordaro, Joseph; ...

    2016-11-10

    Melt state dynamics for a series of strictly linear polyethylenes with precisely spaced associating functional groups were investigated. The periodic pendant acrylic acid groups form hydrogen-bonded acid aggregates within the polyethylene (PE) matrix. The dynamics of these nanoscale heterogeneous morphologies were investigated from picosecond to nanosecond timescales by both quasi-elastic neutron scattering (QENS) measurements and fully atomistic molecular dynamics (MD) simulations. Two dynamic processes were observed. The faster dynamic processes which occur at the picosecond timescales are compositionally insensitive and indicative of spatially restricted local motions. The slower dynamic processes are highly composition dependent and indicate the structural relaxation ofmore » the polymer backbone. Higher acid contents, or shorter PE spacers between pendant acid groups, slow the structural relaxation timescale and increase the stretching parameter (β) of the structural relaxation. Additionally, the dynamics of specific hydrogen atom positions along the backbone correlate structural heterogeneity imposed by the associating acid groups with a mobility gradient along the polymer backbone. At time intervals (<2 ns), the mean-squared displacements for the four methylene groups closest to the acid groups are up to 10 times smaller than those of methylene groups further from the acid groups. At longer timescales acid aggregates rearrange and the chain dynamics of the slow, near-aggregate regions and the faster bridge regions converge, implying a characteristic timescale for the passage of chains between aggregates. As a result, the characterization of the nanoscale chain dynamics in these associating polymer systems both provides validation of simulation force fields and provides understanding of heterogeneous chain dynamics in associating polymers.« less

  15. BEAM DYNAMICS ANALYSIS FOR THE ULTRA-FAST KICKER IN CIRCULAR COOLER RING OF JLEIC

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huang, Yulu; Wang, Haipeng; Rimmer, Robert A.

    An ultra-fast kicker system consisting of four quarter wavelength resonator based deflecting cavities was developed that simultaneously resonates at 10 subharmonic modes of the 476.3MHz bunch repetition frequency. Thus every 10th bunch in the bunch train will experience a transverse kick while all the other bunches are undisturbed. This fast kicker is being developed for the Energy Recovery Linac (ERL) based electron Circular Cooler Ring (CCR) in the proposed Jefferson Lab Electron Ion Collider (JLEIC, previously MEIC). The electron bunches can be reused 10-30 turns thus the beam current in the ERL can be reduced to 1/10 - 1/30 (150mAmore » - 50mA) of the cooling bunch current (1.5A). In this paper, several methods to synthesize such a kicker waveform and the comparison made by the beam dynamics tracking in Elegant will be discussed.« less

  16. Time-scale dynamics of proteome and transcriptome of the white-rot fungus Phlebia radiata: growth on spruce wood and decay effect on lignocellulose.

    PubMed

    Kuuskeri, Jaana; Häkkinen, Mari; Laine, Pia; Smolander, Olli-Pekka; Tamene, Fitsum; Miettinen, Sini; Nousiainen, Paula; Kemell, Marianna; Auvinen, Petri; Lundell, Taina

    2016-01-01

    The white-rot Agaricomycetes species Phlebia radiata is an efficient wood-decaying fungus degrading all wood components, including cellulose, hemicellulose, and lignin. We cultivated P. radiata in solid state cultures on spruce wood, and extended the experiment to 6 weeks to gain more knowledge on the time-scale dynamics of protein expression upon growth and wood decay. Total proteome and transcriptome of P. radiata were analyzed by peptide LC-MS/MS and RNA sequencing at specific time points to study the enzymatic machinery on the fungus' natural growth substrate. According to proteomics analyses, several CAZy oxidoreductase class-II peroxidases with glyoxal and alcohol oxidases were the most abundant proteins produced on wood together with enzymes important for cellulose utilization, such as GH7 and GH6 cellobiohydrolases. Transcriptome additionally displayed expression of multiple AA9 lytic polysaccharide monooxygenases indicative of oxidative cleavage of wood carbohydrate polymers. Large differences were observed for individual protein quantities at specific time points, with a tendency of enhanced production of specific peroxidases on the first 2 weeks of growth on wood. Among the 10 class-II peroxidases, new MnP1-long, characterized MnP2-long and LiP3 were produced in high protein abundances, while LiP2 and LiP1 were upregulated at highest level as transcripts on wood together with the oxidases and one acetyl xylan esterase, implying their necessity as primary enzymes to function against coniferous wood lignin to gain carbohydrate accessibility and fungal growth. Majority of the CAZy encoding transcripts upregulated on spruce wood represented activities against plant cell wall and were identified in the proteome, comprising main activities of white-rot decay. Our data indicate significant changes in carbohydrate-active enzyme expression during the six-week surveillance of P. radiata growing on wood. Response to wood substrate is seen already during the first

  17. A supermassive black hole in an ultra-compact dwarf galaxy.

    PubMed

    Seth, Anil C; van den Bosch, Remco; Mieske, Steffen; Baumgardt, Holger; den Brok, Mark; Strader, Jay; Neumayer, Nadine; Chilingarian, Igor; Hilker, Michael; McDermid, Richard; Spitler, Lee; Brodie, Jean; Frank, Matthias J; Walsh, Jonelle L

    2014-09-18

    Ultra-compact dwarf galaxies are among the densest stellar systems in the Universe. These systems have masses of up to 2 × 10(8) solar masses, but half-light radii of just 3-50 parsecs. Dynamical mass estimates show that many such dwarfs are more massive than expected from their luminosity. It remains unclear whether these high dynamical mass estimates arise because of the presence of supermassive black holes or result from a non-standard stellar initial mass function that causes the average stellar mass to be higher than expected. Here we report adaptive optics kinematic data of the ultra-compact dwarf galaxy M60-UCD1 that show a central velocity dispersion peak exceeding 100 kilometres per second and modest rotation. Dynamical modelling of these data reveals the presence of a supermassive black hole with a mass of 2.1 × 10(7) solar masses. This is 15 per cent of the object's total mass. The high black hole mass and mass fraction suggest that M60-UCD1 is the stripped nucleus of a galaxy. Our analysis also shows that M60-UCD1's stellar mass is consistent with its luminosity, implying a large population of previously unrecognized supermassive black holes in other ultra-compact dwarf galaxies.

  18. Ultra-long Gamma-Ray Bursts from the Collapse of Blue Supergiant Stars: An End-to-end Simulation

    NASA Astrophysics Data System (ADS)

    Perna, Rosalba; Lazzati, Davide; Cantiello, Matteo

    2018-05-01

    Ultra-long gamma-ray bursts (ULGRBs) are a distinct class of GRBs characterized by durations of several thousands of seconds, about two orders of magnitude longer than those of standard long GRBs (LGRBs). The driving engine of these events has not yet been uncovered, and ideas range from magnetars, to tidal disruption events, to extended massive stars, such as blue super giants (BSG). BSGs, a possible endpoint of stellar evolution, are attractive for the relatively long freefall times of their envelopes, allowing accretion to power a long-lasting central engine. At the same time, their large radial extension poses a challenge to the emergence of a jet. Here, we perform an end-to-end simulation aimed at assessing the viability of BSGs as ULGRB progenitors. The evolution to the core-collapse of a BSG star model is calculated with the MESA code. We then compute the accretion rate for the fraction of envelope material with enough angular momentum to circularize and form an accretion disk, and input the corresponding power into a jet, which we evolve through the star envelope with the FLASH code. Our simulation shows that the jet can emerge, and the resulting light curves resemble those observed in ULGRBs, with durations T 90 ranging from ≈4000 s to ≈104 s, depending on the viewing angle.

  19. Longitudinal long-period dynamics of aerospace craft

    NASA Technical Reports Server (NTRS)

    Berry, Donald T.

    1988-01-01

    Linear analyses are performed to examine the generic aspects of aerospace vehicle longitudinal long-period or trajectory modes of motion. The influence of Mach number, dynamic pressure, thrust-to-drag ratio, and propulsion system thrust laws on the longitudinal trajectory modes is presented in terms of phugoid frequency and damping and height mode stability. The results of these analyses are compared to flying qualities requirements where possible, and potential deficiencies in both the vehicle and the criteria are noted. A preliminary look at possible augmentation schemes to improve potential deficiencies is also presented. Interpretation of the practical consequences of the results is aided by typical time histories. Results indicate that propulsion system characteristics are the dominant influence on the longitudinal long-period flight dynamics of hypersonic aerospace craft. However, straightforward augmentation systems demonstrated the potential to accommodate these influences if the effects are included in the design process. These efforts may be hampered by a lack of design criteria for hypersonic aircraft.

  20. Towards fast, rigorous and efficient conformational sampling of biomolecules: Advances in accelerated molecular dynamics.

    PubMed

    Doshi, Urmi; Hamelberg, Donald

    2015-05-01

    Accelerated molecular dynamics (aMD) has been proven to be a powerful biasing method for enhanced sampling of biomolecular conformations on general-purpose computational platforms. Biologically important long timescale events that are beyond the reach of standard molecular dynamics can be accessed without losing the detailed atomistic description of the system in aMD. Over other biasing methods, aMD offers the advantages of tuning the level of acceleration to access the desired timescale without any advance knowledge of the reaction coordinate. Recent advances in the implementation of aMD and its applications to small peptides and biological macromolecules are reviewed here along with a brief account of all the aMD variants introduced in the last decade. In comparison to the original implementation of aMD, the recent variant in which all the rotatable dihedral angles are accelerated (RaMD) exhibits faster convergence rates and significant improvement in statistical accuracy of retrieved thermodynamic properties. RaMD in conjunction with accelerating diffusive degrees of freedom, i.e. dual boosting, has been rigorously tested for the most difficult conformational sampling problem, protein folding. It has been shown that RaMD with dual boosting is capable of efficiently sampling multiple folding and unfolding events in small fast folding proteins. RaMD with the dual boost approach opens exciting possibilities for sampling multiple timescales in biomolecules. While equilibrium properties can be recovered satisfactorily from aMD-based methods, directly obtaining dynamics and kinetic rates for larger systems presents a future challenge. This article is part of a Special Issue entitled Recent developments of molecular dynamics. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. One-year clinical outcomes of ultra long apollo polymer-based Paclitaxel-eluting stents in patients with complex, long coronary artery lesions.

    PubMed

    Salarifar, Mojtaba; Kassaian, Seyed Ebrahim; Alidoosti, Mohammad; Haji-Zeinali, Ali Mohammad; Poorhoseini, Hamid Reza; Nematipour, Ebrahim; Amirzadegan, Alireza; Saroukhani, Sepideh

    2011-01-01

    For all the wealth of research comparing the efficacy of the different types of the drug-eluting stent (DES) such as sirolimus-, paclitaxel-, and zotarolimus-eluting stents, there is still a dearth of data on the different brands of each DES type. We aimed to investigate the one-year clinical outcomes, including major adverse cardiac events (MACE), of the use of the ultra long Apollo paclitaxel-eluting stent in patients with long atherosclerotic coronary artery lesions. According to a retrospective review of the Tehran Heart Center Registry of Interventional Cardiology, a single-center nonrandomized computerized data registry in which all adult patients who undergo single or multi-vessel percutaneous coronary intervention (PCI) are enrolled without any specific exclusion criteria, the mixed use of long Apollo paclitaxel-eluting stents and other types of the DES as well as myocardial infarction within forty-eight hours prior to the procedure was excluded. In total, 122 patients were enrolled in the study, and their baseline clinical, angiographic, and procedural characteristics were obtained. In addition, the patients' follow-up data and, most importantly, MACE during a one-year period after intervention were recorded. The mean follow-up duration was 14.1 ± 3.8 months. The one-year clinical follow-up data were obtained in 95.9 % of all the patients. The incidence of MACE was 5.7% during the entire study period. There was 1 death, which occurred during the initial days after PCI. The incidence of non-fatal myocardial infarction was 2.5% (3 cases), including one patient who underwent target vessel revascularization seven months later. Also, 3 patients with single-vessel disease and in-stent restenosis underwent coronary artery bypass grafting between five to ten months later. Our results showed that the Apollo paclitaxel-eluting stent might be regarded as a safe and effective treatment for long coronary lesions.

  2. Effective long wavelength scalar dynamics in de Sitter

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moss, Ian; Rigopoulos, Gerasimos, E-mail: ian.moss@newcastle.ac.uk, E-mail: gerasimos.rigopoulos@ncl.ac.uk

    We discuss the effective infrared theory governing a light scalar's long wavelength dynamics in de Sitter spacetime. We show how the separation of scales around the physical curvature radius k / a ∼ H can be performed consistently with a window function and how short wavelengths can be integrated out in the Schwinger-Keldysh path integral formalism. At leading order, and for time scales Δ t >> H {sup −1}, this results in the well-known Starobinsky stochastic evolution. However, our approach allows for the computation of quantum UV corrections, generating an effective potential on which the stochastic dynamics takes place. Themore » long wavelength stochastic dynamical equations are now second order in time, incorporating temporal scales Δ t ∼ H {sup −1} and resulting in a Kramers equation for the probability distribution—more precisely the Wigner function—in contrast to the more usual Fokker-Planck equation. This feature allows us to non-perturbatively evaluate, within the stochastic formalism, not only expectation values of field correlators, but also the stress-energy tensor of φ.« less

  3. Timescale of Destabilization of a Magma Ocean Cumulate

    NASA Astrophysics Data System (ADS)

    Morison, A.; Labrosse, S.; Deguen, R.; Alboussiere, T.

    2017-12-01

    A common scenario considered during the formation of terrestrial planets is the crystallization of a global magma ocean from the bottom-up. The crystallization of the surface magma ocean is expected to be rapid, on a timescale of the order of 1 Myr. This has lead several authors to assume convection in the solid part of the crystallizing mantle only sets out after the complete solidification of the surface magma ocean. Assuming fractionnal crystallization of this ocean, the magma (and resulting solid) is more and more enriched in FeO as the crystallization progresses. This leads to an unstable stratification and an overturn. After overturn, the resulting solid mantle would be strongly compositionally stratified. The present study tests the assumption that solid-state mantle overturn only occurs after complete crystallization of the surface magma ocean. We model convection in the solid part of the mantle only and parametrize the presence of a magma ocean with boundary conditions. Our model includes through these boundary conditions the possibility for matter to cross the boundary between the solid shell and the magma ocean by melting and freezing. We perfomed a linear stability analysis with respect to the temperature and compositional profiles obtained in a growing magma ocean cumulate to assess the destabilization timescale of such profiles as a function of the crystallized thickness. By comparing this timescale with a model of surface magma ocean crystallization, we deduce the time and crystallized thickness at which the convection timescale is comparable to the age of the solid crystallizing mantle. This time is found to be small ( 1 kyr) compared to the time needed to crystallize the entire surface magma ocean ( 1 Myr).

  4. Timescales of AMOC decline in response to fresh water forcing

    NASA Astrophysics Data System (ADS)

    Jackson, Laura C.; Wood, Richard A.

    2017-12-01

    The Atlantic meridional overturning circulation (AMOC) is predicted to weaken over the coming century due to warming from greenhouse gases and increased input of fresh water into the North Atlantic, however there is considerable uncertainty as to the amount and rate of AMOC weakening. Understanding what controls the rate and timescale of AMOC weakening may help to reduce this uncertainty and hence reduce the uncertainty surrounding associated impacts. As a first step towards this we consider the timescales associated with weakening in response to idealized freshening scenarios. Here we explore timescales of AMOC weakening in response to a freshening of the North Atlantic in a suite of experiments with an eddy-permitting global climate model (GCM). When the rate of fresh water added to the North Atlantic is small (0.1 Sv; 1 Sv =1× 10^6 m^3 /s), the timescale of AMOC weakening depends mainly on the rate of fresh water input itself and can be longer than a century. When the rate of fresh water added is large (≥ 0.3 Sv) however, the timescale is a few decades and is insensitive to the actual rate of fresh water input. This insensitivity is because with a greater rate of fresh water input the advective feedbacks become more important at exporting fresh anomalies, so the rate of freshening is similar. We find advective feedbacks from: an export of fresh anomalies by the mean flow; less volume import through the Bering Strait; a weakening AMOC transporting less subtropical water northwards; and anomalous subtropical circulations which amplify export of the fresh anomalies. This latter circulation change is driven itself by the presence of fresh anomalies exported from the subpolar gyre through geostrophy. This feedback has not been identified in previous model studies and when the rate of freshening is strong it is found to dominate the total export of fresh anomalies, and hence the timescale of AMOC decline. Although results may be model dependent, qualitatively

  5. A challenge to chaotic itinerancy from brain dynamics

    NASA Astrophysics Data System (ADS)

    Kay, Leslie M.

    2003-09-01

    Brain hermeneutics and chaotic itinerancy proposed by Tsuda are attractive characterizations of perceptual dynamics in the mammalian olfactory system. This theory proposes that perception occurs at the interface between itinerant neural representation and interaction with the environment. Quantifiable application of these dynamics has been hampered by the lack of definable history and action processes which characterize the changes induced by behavioral state, attention, and learning. Local field potentials measured from several brain areas were used to characterize dynamic activity patterns for their use as representations of history and action processes. The signals were recorded from olfactory areas (olfactory bulb, OB, and pyriform cortex) and hippocampal areas (entorhinal cortex and dentate gyrus, DG) in the brains of rats. During odor-guided behavior the system shows dynamics at three temporal scales. Short time-scale changes are system-wide and can occur in the space of a single sniff. They are predictable, associated with learned shifts in behavioral state and occur periodically on the scale of the intertrial interval. These changes occupy the theta (2-12 Hz), beta (15-30 Hz), and gamma (40-100 Hz) frequency bands within and between all areas. Medium time-scale changes occur relatively unpredictably, manifesting in these data as alterations in connection strength between the OB and DG. These changes are strongly correlated with performance in associated trial blocks (5-10 min) and may be due to fluctuations in attention, mood, or amount of reward received. Long time-scale changes are likely related to learning or decline due to aging or disease. These may be modeled as slow monotonic processes that occur within or across days or even weeks or years. The folding of different time scales is proposed as a mechanism for chaotic itinerancy, represented by dynamic processes instead of static connection strengths. Thus, the individual maintains continuity of

  6. Detection of ultra-low oxygen concentration based on the fluorescence blinking dynamics of single molecules

    NASA Astrophysics Data System (ADS)

    Wu, Ruixiang; Chen, Ruiyun; Zhou, Haitao; Qin, Yaqiang; Zhang, Guofeng; Qin, Chengbing; Gao, Yan; Gao, Yajun; Xiao, Liantuan; Jia, Suotang

    2018-01-01

    We present a sensitive method for detection of ultra-low oxygen concentrations based on the fluorescence blinking dynamics of single molecules. The relationship between the oxygen concentration and the fraction of time spent in the off-state, stemming from the population and depopulation of triplet states and radical cationic states, can be fitted with a two-site quenching model in the Stern-Volmer plot. The oxygen sensitivity is up to 43.42 kPa-1 in the oxygen partial pressure region as low as 0.01-0.25 kPa, which is seven times higher than that of the fluorescence intensity indicator. This method avoids the limitation of the sharp and non-ignorable fluctuations that occur during the measurement of fluorescence intensity, providing potential applications in the field of low oxygen-concentration monitoring in life science and industry.

  7. Anomalous dynamical phase in quantum spin chains with long-range interactions

    NASA Astrophysics Data System (ADS)

    Homrighausen, Ingo; Abeling, Nils O.; Zauner-Stauber, Valentin; Halimeh, Jad C.

    2017-09-01

    The existence or absence of nonanalytic cusps in the Loschmidt-echo return rate is traditionally employed to distinguish between a regular dynamical phase (regular cusps) and a trivial phase (no cusps) in quantum spin chains after a global quench. However, numerical evidence in a recent study (J. C. Halimeh and V. Zauner-Stauber, arXiv:1610.02019) suggests that instead of the trivial phase, a distinct anomalous dynamical phase characterized by a novel type of nonanalytic cusps occurs in the one-dimensional transverse-field Ising model when interactions are sufficiently long range. Using an analytic semiclassical approach and exact diagonalization, we show that this anomalous phase also arises in the fully connected case of infinite-range interactions, and we discuss its defining signature. Our results show that the transition from the regular to the anomalous dynamical phase coincides with Z2-symmetry breaking in the infinite-time limit, thereby showing a connection between two different concepts of dynamical criticality. Our work further expands the dynamical phase diagram of long-range interacting quantum spin chains, and can be tested experimentally in ion-trap setups and ultracold atoms in optical cavities, where interactions are inherently long range.

  8. The propagation of varied timescale perturbations in landscapes

    NASA Astrophysics Data System (ADS)

    Bingham, N.; Johnson, K. N.; Bookhagen, B.; Chadwick, O.

    2016-12-01

    The classic assumption of steady-state landscapes greatly simplifies models of earth-surface processes. Theoretically, steady-state denotes time independence, but in real landscapes steady-state requires a timescale over which to assume (or document) no change. In the past, poor spatiotemporal resolution of eroding landscapes necessitated that shorter timescale perturbations be ignored in favor of regional formulations of rock uplift = erosion, 105, 6 years. Now, novel techniques and technologies provide an opportunity to define local landscape response to various timescales of perturbations; thus, allowing us to consider multiple steady-states on adjacent watersheds or even along a single watershed. This study seeks to identify the physical propagation of varied timescale perturbations in landscapes in order to provide an updated geomorphic context for interpreting critical zone processes. At our study site - Santa Cruz Island (SCI), CA - perturbations include sea level and climate fluctuations over 105 years coupled with pulses of overgrazing and extreme storm events during the last 200 years. Comprehensive knickpoint location maps and dated marine and fill terraces tighten the spatiotemporal constraints on erosion for SCI. In addition, the island hosts a wide range of lithologies, allowing us to compare lithologic effects on landscape response to perturbations. Our study uses lidar point clouds and high resolution (0.25 and 1 m) digital elevation model analysis to segment landscapes by the degree of their response to perturbations. Landscape response is measured by increases in topographic roughness. We ascertain roughness by analyzing the changes in different terrain attributes on multiple spatial scales: catchment, sub-catchments and individual hillslopes. Terrain attributes utilized include slope, curvature, local relief, flowpath length and contributing catchment area. Statistical analysis of these properties indicates narrower ranges in values for regions

  9. Integrating cell on chip—Novel waveguide platform employing ultra-long optical paths

    NASA Astrophysics Data System (ADS)

    Fohrmann, Lena Simone; Sommer, Gerrit; Pitruzzello, Giampaolo; Krauss, Thomas F.; Petrov, Alexander Yu.; Eich, Manfred

    2017-09-01

    Optical waveguides are the most fundamental building blocks of integrated optical circuits. They are extremely well understood, yet there is still room for surprises. Here, we introduce a novel 2D waveguide platform which affords a strong interaction of the evanescent tail of a guided optical wave with an external medium while only employing a very small geometrical footprint. The key feature of the platform is its ability to integrate the ultra-long path lengths by combining low propagation losses in a silicon slab with multiple reflections of the guided wave from photonic crystal (PhC) mirrors. With a reflectivity of 99.1% of our tailored PhC-mirrors, we achieve interaction paths of 25 cm within an area of less than 10 mm2. This corresponds to 0.17 dB/cm effective propagation which is much lower than the state-of-the-art loss of approximately 1 dB/cm of single mode silicon channel waveguides. In contrast to conventional waveguides, our 2D-approach leads to a decay of the guided wave power only inversely proportional to the optical path length. This entirely different characteristic is the major advantage of the 2D integrating cell waveguide platform over the conventional channel waveguide concepts that obey the Beer-Lambert law.

  10. Investigating Small-Molecule Ligand Binding to G Protein-Coupled Receptors with Biased or Unbiased Molecular Dynamics Simulations.

    PubMed

    Marino, Kristen A; Filizola, Marta

    2018-01-01

    An increasing number of G protein-coupled receptor (GPCR) crystal structures provide important-albeit static-pictures of how small molecules or peptides interact with their receptors. These high-resolution structures represent a tremendous opportunity to apply molecular dynamics (MD) simulations to capture atomic-level dynamical information that is not easy to obtain experimentally. Understanding ligand binding and unbinding processes, as well as the related responses of the receptor, is crucial to the design of better drugs targeting GPCRs. Here, we discuss possible ways to study the dynamics involved in the binding of small molecules to GPCRs, using long timescale MD simulations or metadynamics-based approaches.

  11. Investigating Small-Molecule Ligand Binding to G Protein-Coupled Receptors with Biased or Unbiased Molecular Dynamics Simulations

    PubMed Central

    Marino, Kristen A.; Filizola, Marta

    2017-01-01

    An increasing number of G protein-coupled receptor (GPCR) crystal structures provide important—albeit static—pictures of how small molecules or peptides interact with their receptors. These high-resolution structures represent a tremendous opportunity to apply molecular dynamics (MD) simulations to capture atomic-level dynamical information that is not easy to obtain experimentally. Understanding ligand binding and unbinding processes, as well as the related responses of the receptor, is crucial to the design of better drugs targeting GPCRs. Here, we discuss possible ways to study the dynamics involved in the binding of small molecules to GPCRs, using long timescale MD simulations or metadynamics-based approaches. PMID:29188572

  12. Ultrafast energy- and momentum-resolved dynamics of magnetic correlations in the photo-doped Mott insulator Sr2IrO4.

    PubMed

    Dean, M P M; Cao, Y; Liu, X; Wall, S; Zhu, D; Mankowsky, R; Thampy, V; Chen, X M; Vale, J G; Casa, D; Kim, Jungho; Said, A H; Juhas, P; Alonso-Mori, R; Glownia, J M; Robert, A; Robinson, J; Sikorski, M; Song, S; Kozina, M; Lemke, H; Patthey, L; Owada, S; Katayama, T; Yabashi, M; Tanaka, Yoshikazu; Togashi, T; Liu, J; Rayan Serrao, C; Kim, B J; Huber, L; Chang, C-L; McMorrow, D F; Först, M; Hill, J P

    2016-06-01

    Measuring how the magnetic correlations evolve in doped Mott insulators has greatly improved our understanding of the pseudogap, non-Fermi liquids and high-temperature superconductivity. Recently, photo-excitation has been used to induce similarly exotic states transiently. However, the lack of available probes of magnetic correlations in the time domain hinders our understanding of these photo-induced states and how they could be controlled. Here, we implement magnetic resonant inelastic X-ray scattering at a free-electron laser to directly determine the magnetic dynamics after photo-doping the Mott insulator Sr2IrO4. We find that the non-equilibrium state, 2 ps after the excitation, exhibits strongly suppressed long-range magnetic order, but hosts photo-carriers that induce strong, non-thermal magnetic correlations. These two-dimensional (2D) in-plane Néel correlations recover within a few picoseconds, whereas the three-dimensional (3D) long-range magnetic order restores on a fluence-dependent timescale of a few hundred picoseconds. The marked difference in these two timescales implies that the dimensionality of magnetic correlations is vital for our understanding of ultrafast magnetic dynamics.

  13. Ultrafast energy- and momentum-resolved dynamics of magnetic correlations in the photo-doped Mott insulator Sr 2IrO 4

    DOE PAGES

    Dean, M. P. M.; Cao, Y.; Liu, X.; ...

    2016-05-09

    Measuring how the magnetic correlations evolve in doped Mott insulators has greatly improved our understanding of the pseudogap, non-Fermi liquids and high-temperature superconductivity 1, 2, 3, 4. Recently, photo-excitation has been used to induce similarly exotic states transiently 5, 6, 7. However, the lack of available probes of magnetic correlations in the time domain hinders our understanding of these photo-induced states and how they could be controlled. Here, we implement magnetic resonant inelastic X-ray scattering at a free-electron laser to directly determine the magnetic dynamics after photo-doping the Mott insulator Sr 2IrO 4. We find that the non-equilibrium state, 2more » ps after the excitation, exhibits strongly suppressed long-range magnetic order, but hosts photo-carriers that induce strong, non-thermal magnetic correlations. These two-dimensional (2D) in-plane Néel correlations recover within a few picoseconds, whereas the three-dimensional (3D) long-range magnetic order restores on a fluence-dependent timescale of a few hundred picoseconds. In conclusion, the marked difference in these two timescales implies that the dimensionality of magnetic correlations is vital for our understanding of ultrafast magnetic dynamics.« less

  14. Temporal dynamics of frequency-tunable graphene-based plasmonic grating structures for ultra-broadband terahertz communication

    NASA Astrophysics Data System (ADS)

    Jornet, Josep Miquel; Thawdar, Ngwe; Woo, Ethan; Andrello, Michael A.

    2017-05-01

    Terahertz (THz) communication is envisioned as a key wireless technology to satisfy the need for 1000x faster wireless data rates. To date, major progress on both electronic and photonic technologies are finally closing the so-called THz gap. Among others, graphene-based plasmonic nano-devices have been proposed as a way to enable ultra-broadband communications above 1THz. The unique dynamic complex conductivity of graphene enables the propagation of Surface Plasmon Polariton (SPP) waves at THz frequencies. In addition, the conductivity of graphene and, thus, the SPP propagation properties, can be dynamically tuned by means of electrostatic biasing or material doping. This result opens the door to frequency-tunable devices for THz communications. In this paper, the temporal dynamics of graphene-enhanced metallic grating structures used for excitation and detection of SPP waves at THz frequencies are analytically and numerically modeled. More specifically, the response of a metallic grating structure built on top of a graphene-based heterostructure is analyzed by taking into account the grating period and duty cycle and the Fermi energy of the graphene layer. Then, the interfacial charge transfer between a metallic back-gate and the graphene layer in a metal/dielectric/graphene stack is analytically modeled, and the range of achievable Fermi energies is determined. Finally, the rate at which the Fermi energy in graphene can be tuned is estimated starting from the transmission line model of graphene. Extensive numerical and simulation results with COMSOL Multi-physics are provided. The results show that the proposed structure enables dynamic frequency systems with THz bandwidths, thus, enabling resilient communication techniques such as time-hopping THz modulations.

  15. Weighing Ultra-Cool Stars

    NASA Astrophysics Data System (ADS)

    2004-05-01

    Large Ground-Based Telescopes and Hubble Team-Up to Perform First Direct Brown Dwarf Mass Measurement [1] Summary Using ESO's Very Large Telescope at Paranal and a suite of ground- and space-based telescopes in a four-year long study, an international team of astronomers has measured for the first time the mass of an ultra-cool star and its companion brown dwarf. The two stars form a binary system and orbit each other in about 10 years. The team obtained high-resolution near-infrared images; on the ground, they defeated the blurring effect of the terrestrial atmosphere by means of adaptive optics techniques. By precisely determining the orbit projected on the sky, the astronomers were able to measure the total mass of the stars. Additional data and comparison with stellar models then yield the mass of each of the components. The heavier of the two stars has a mass around 8.5% of the mass of the Sun and its brown dwarf companion is even lighter, only 6% of the solar mass. Both objects are relatively young with an age of about 500-1,000 million years. These observations represent a decisive step towards the still missing calibration of stellar evolution models for very-low mass stars. PR Photo 19a/04: Orbit of the ultra-cool stars in 2MASSW J0746425+2000321. PR Photo 19b/04: Animated Gif of the orbital motion. Telephone number star Even though astronomers have found several hundreds of very low mass stars and brown dwarfs, the fundamental properties of these extreme objects, such as masses and surface temperatures, are still not well known. Within the cosmic zoo, these ultra-cool stars represent a class of "intermediate" objects between giant planets - like Jupiter - and "normal" stars less massive than our Sun, and to understand them well is therefore crucial to the field of stellar astrophysics. The problem with these ultra-cool stars is that contrary to normal stars that burn hydrogen in their central core, no unique relation exists between the luminosity of the

  16. Global mapping of nonseismic sea level oscillations at tsunami timescales.

    PubMed

    Vilibić, Ivica; Šepić, Jadranka

    2017-01-18

    Present investigations of sea level extremes are based on hourly data measured at coastal tide gauges. The use of hourly data restricts existing global and regional analyses to periods larger than 2 h. However, a number of processes occur at minute timescales, of which the most ruinous are tsunamis. Meteotsunamis, hazardous nonseismic waves that occur at tsunami timescales over limited regions, may also locally dominate sea level extremes. Here, we show that nonseismic sea level oscillations at tsunami timescales (<2 h) may substantially contribute to global sea level extremes, up to 50% in low-tidal basins. The intensity of these oscillations is zonally correlated with mid-tropospheric winds at the 99% significance level, with the variance doubling from the tropics and subtropics to the mid-latitudes. Specific atmospheric patterns are found during strong events at selected locations in the World Ocean, indicating a globally predominant generation mechanism. Our analysis suggests that these oscillations should be considered in sea level hazard assessment studies. Establishing a strong correlation between nonseismic sea level oscillations at tsunami timescales and atmospheric synoptic patterns would allow for forecasting of nonseismic sea level oscillations for operational use, as well as hindcasting and projection of their effects under past, present and future climates.

  17. Global mapping of nonseismic sea level oscillations at tsunami timescales

    PubMed Central

    Vilibić, Ivica; Šepić, Jadranka

    2017-01-01

    Present investigations of sea level extremes are based on hourly data measured at coastal tide gauges. The use of hourly data restricts existing global and regional analyses to periods larger than 2 h. However, a number of processes occur at minute timescales, of which the most ruinous are tsunamis. Meteotsunamis, hazardous nonseismic waves that occur at tsunami timescales over limited regions, may also locally dominate sea level extremes. Here, we show that nonseismic sea level oscillations at tsunami timescales (<2 h) may substantially contribute to global sea level extremes, up to 50% in low-tidal basins. The intensity of these oscillations is zonally correlated with mid-tropospheric winds at the 99% significance level, with the variance doubling from the tropics and subtropics to the mid-latitudes. Specific atmospheric patterns are found during strong events at selected locations in the World Ocean, indicating a globally predominant generation mechanism. Our analysis suggests that these oscillations should be considered in sea level hazard assessment studies. Establishing a strong correlation between nonseismic sea level oscillations at tsunami timescales and atmospheric synoptic patterns would allow for forecasting of nonseismic sea level oscillations for operational use, as well as hindcasting and projection of their effects under past, present and future climates. PMID:28098195

  18. Long-term variability of T Tauri stars using WASP

    NASA Astrophysics Data System (ADS)

    Rigon, Laura; Scholz, Alexander; Anderson, David; West, Richard

    2017-03-01

    We present a reference study of the long-term optical variability of young stars using data from the WASP project. Our primary sample is a group of well-studied classical T Tauri stars (CTTSs), mostly in Taurus-Auriga. WASP light curves cover time-scales of up to 7 yr and typically contain 10 000-30 000 data points. We quantify the variability as a function of time-scale using the time-dependent standard deviation 'pooled sigma'. We find that the overwhelming majority of CTTSs have a low-level variability with σ < 0.3 mag dominated by time-scales of a few weeks, consistent with rotational modulation. Thus, for most young stars, monitoring over a month is sufficient to constrain the total amount of variability over time-scales of up to a decade. The fraction of stars with a strong optical variability (σ > 0.3 mag) is 21 per cent in our sample and 21 per cent in an unbiased control sample. An even smaller fraction (13 per cent in our sample, 6 per cent in the control) show evidence for an increase in variability amplitude as a function of time-scale from weeks to months or years. The presence of long-term variability correlates with the spectral slope at 3-5 μm, which is an indicator of inner disc geometry, and with the U-B band slope, which is an accretion diagnostics. This shows that the long-term variations in CTTSs are predominantly driven by processes in the inner disc and in the accretion zone. Four of the stars with long-term variations show periods of 20-60 d, significantly longer than the rotation periods and stable over months to years. One possible explanation is cyclic changes in the interaction between the disc and the stellar magnetic field.

  19. Antenna design and implementation for the future space Ultra-Long wavelength radio telescope

    NASA Astrophysics Data System (ADS)

    Chen, Linjie; Aminaei, Amin; Gurvits, Leonid I.; Wolt, Marc Klein; Pourshaghaghi, Hamid Reza; Yan, Yihua; Falcke, Heino

    2018-04-01

    In radio astronomy, the Ultra-Long Wavelengths (ULW) regime of longer than 10 m (frequencies below 30 MHz), remains the last virtually unexplored window of the celestial electromagnetic spectrum. The strength of the science case for extending radio astronomy into the ULW window is growing. However, the opaqueness of the Earth's ionosphere makes ULW observations by ground-based facilities practically impossible. Furthermore, the ULW spectrum is full of anthropogenic radio frequency interference (RFI). The only radical solution for both problems is in placing an ULW astronomy facility in space. We present a concept of a key element of a space-borne ULW array facility, an antenna that addresses radio astronomical specifications. A tripole-type antenna and amplifier are analysed as a solution for ULW implementation. A receiver system with a low power dissipation is discussed as well. The active antenna is optimized to operate at the noise level defined by the celestial emission in the frequency band 1 - 30 MHz. Field experiments with a prototype tripole antenna enabled estimates of the system noise temperature. They indicated that the proposed concept meets the requirements of a space-borne ULW array facility.

  20. Synaptic dynamics contribute to long-term single neuron response fluctuations.

    PubMed

    Reinartz, Sebastian; Biro, Istvan; Gal, Asaf; Giugliano, Michele; Marom, Shimon

    2014-01-01

    Firing rate variability at the single neuron level is characterized by long-memory processes and complex statistics over a wide range of time scales (from milliseconds up to several hours). Here, we focus on the contribution of non-stationary efficacy of the ensemble of synapses-activated in response to a given stimulus-on single neuron response variability. We present and validate a method tailored for controlled and specific long-term activation of a single cortical neuron in vitro via synaptic or antidromic stimulation, enabling a clear separation between two determinants of neuronal response variability: membrane excitability dynamics vs. synaptic dynamics. Applying this method we show that, within the range of physiological activation frequencies, the synaptic ensemble of a given neuron is a key contributor to the neuronal response variability, long-memory processes and complex statistics observed over extended time scales. Synaptic transmission dynamics impact on response variability in stimulation rates that are substantially lower compared to stimulation rates that drive excitability resources to fluctuate. Implications to network embedded neurons are discussed.

  1. Mesoporous TiO2 nanosheets anchored on graphene for ultra long life Na-ion batteries.

    PubMed

    Zhang, Ruifang; Wang, Yuankun; Zhou, Han; Lang, Jinxin; Xu, Jingjing; Xiang, Yang; Ding, Shujiang

    2018-06-01

    Sodium-ion batteries, which have a similar electrochemical reaction mechanism to lithium-ion batteries, have been considered as one of the most potential lithium-ion battery alternatives due to the rich reserves of sodium. However, it is very hard to find appropriate electrode materials imputing the large radius of sodium-ion. TiO 2 is particularly interesting as anodes for sodium-ion batteries due to their reasonable operation voltage, cost, and nontoxicity. To obtain a better electrochemical property, mesoporous TiO 2 nanosheets (NSs)/reduced graphene oxide (rGO) composites have been synthesized via a scalable hydrothermal-solvothermal method with a subsequent calcination process. Benefitting from unique structure design, TiO 2 NSs@rGO exhibits a superior cycle stability (90 mAh g -1 after 10 000 cycles at a high current rate of 20 C) and satisfactory rate performance (97.3 mAh g -1 at 25 C). To our knowledge, such ultra long cycle life has not previously been reported.

  2. Mesoporous TiO2 nanosheets anchored on graphene for ultra long life Na-ion batteries

    NASA Astrophysics Data System (ADS)

    Zhang, Ruifang; Wang, Yuankun; Zhou, Han; Lang, Jinxin; Xu, Jingjing; Xiang, Yang; Ding, Shujiang

    2018-06-01

    Sodium-ion batteries, which have a similar electrochemical reaction mechanism to lithium-ion batteries, have been considered as one of the most potential lithium-ion battery alternatives due to the rich reserves of sodium. However, it is very hard to find appropriate electrode materials imputing the large radius of sodium-ion. TiO2 is particularly interesting as anodes for sodium-ion batteries due to their reasonable operation voltage, cost, and nontoxicity. To obtain a better electrochemical property, mesoporous TiO2 nanosheets (NSs)/reduced graphene oxide (rGO) composites have been synthesized via a scalable hydrothermal-solvothermal method with a subsequent calcination process. Benefitting from unique structure design, TiO2 NSs@rGO exhibits a superior cycle stability (90 mAh g‑1 after 10 000 cycles at a high current rate of 20 C) and satisfactory rate performance (97.3 mAh g‑1 at 25 C). To our knowledge, such ultra long cycle life has not previously been reported.

  3. Ultra-long Duration Balloon Mission Concept Study: EXIST-LITE Hard X-ray Imaging Survey

    NASA Technical Reports Server (NTRS)

    2003-01-01

    We carried out a mission concept Study for an ultra-long duration balloon (ULDB) mission to conduct a high-sensitivity hard x-ray (approx. 20-600 keV) imaging sky survey. The EXIST-LITE concept has been developed, and critical detector technologies for realistic fabrication of very large area Cd-Zn-Te imaging detector arrays are now much better understood. A ULDB mission such as EXIST-LITE is now even more attractive as a testbed for the full Energetic X-ray Imaging Survey Telescope (EXIST) mission, recommended by the Decadal Survey, and now included in the NASA Roadmap and Strategic Plan as one of the 'Einstein Probes'. In this (overdue!) Final Report we provide a brief update for the science opportunities possible with a ULDB mission such as EXIST-LITE and relate these to upcoming missions (INTErnational Gamma-Ray Astrophysics Laboratory (INTEGRAL) and Swift) as well as the ultimate very high sensitivity sky survey mission EXIST. We then review the progress made over this investigation in Detector/Telescope design concept, Gondola and Mission design concept, and Data Handling/Analysis.

  4. Short-timescale γ-Ray Variability in CTA 102

    NASA Astrophysics Data System (ADS)

    Shukla, A.; Mannheim, K.; Patel, S. R.; Roy, J.; Chitnis, V. R.; Dorner, D.; Rao, A. R.; Anupama, G. C.; Wendel, C.

    2018-02-01

    The flat-spectrum radio quasar CTA 102 experienced a prolonged state of enhanced activity across the entire observed electromagnetic spectrum during 2016–2017, most pronounced during a major outburst between 2016 December and 2017 May. Fermi-LAT observed a flux of (2.2 ± 0.2) × 10‑5 photons cm‑2 s‑1 at energies above 100 MeV on 2017 April 19 during a single orbit. We report here the detection of significant (4.7σ) flux variations down to timescales of ∼5 minutes during this orbit. The measured variability timescale is much shorter than the light-travel time across the central black hole (∼70 minutes) indicating a very compact emission region within the jet, similar to that seen in IC 310, Mrk 501, or PKS 1222+21 from MAGIC observations. This short-timescale variability is unexpected since the γ-ray spectrum shows no sign of attenuation due to pair creation in interactions with photons from the broad emission line region, and therefore must be assumed to originate far from the black hole. The observed fast variability could either indicate the dissipation of magnetic islands or protons in a collimated beam from the base of the jet encountering the turbulent plasma at the end of the magnetic nozzle.

  5. Signal-independent timescale analysis (SITA) and its application for neural coding during reaching and walking.

    PubMed

    Zacksenhouse, Miriam; Lebedev, Mikhail A; Nicolelis, Miguel A L

    2014-01-01

    What are the relevant timescales of neural encoding in the brain? This question is commonly investigated with respect to well-defined stimuli or actions. However, neurons often encode multiple signals, including hidden or internal, which are not experimentally controlled, and thus excluded from such analysis. Here we consider all rate modulations as the signal, and define the rate-modulations signal-to-noise ratio (RM-SNR) as the ratio between the variance of the rate and the variance of the neuronal noise. As the bin-width increases, RM-SNR increases while the update rate decreases. This tradeoff is captured by the ratio of RM-SNR to bin-width, and its variations with the bin-width reveal the timescales of neural activity. Theoretical analysis and simulations elucidate how the interactions between the recovery properties of the unit and the spectral content of the encoded signals shape this ratio and determine the timescales of neural coding. The resulting signal-independent timescale analysis (SITA) is applied to investigate timescales of neural activity recorded from the motor cortex of monkeys during: (i) reaching experiments with Brain-Machine Interface (BMI), and (ii) locomotion experiments at different speeds. Interestingly, the timescales during BMI experiments did not change significantly with the control mode or training. During locomotion, the analysis identified units whose timescale varied consistently with the experimentally controlled speed of walking, though the specific timescale reflected also the recovery properties of the unit. Thus, the proposed method, SITA, characterizes the timescales of neural encoding and how they are affected by the motor task, while accounting for all rate modulations.

  6. Ultra-low dose naltrexone enhances cannabinoid-induced antinociception.

    PubMed

    Paquette, Jay; Olmstead, Mary C; Olmstead, Mary

    2005-12-01

    Both opioids and cannabinoids have inhibitory effects at micromolar doses, which are mediated by activated receptors coupling to Gi/o-proteins. Surprisingly, the analgesic effects of opioids are enhanced by ultra-low doses (nanomolar to picomolar) of the opioid antagonist, naltrexone. As opioid and cannabinoid systems interact, this study investigated whether ultra-low dose naltrexone also influences cannabinoid-induced antinociception. Separate groups of Long-Evans rats were tested for antinociception following an injection of vehicle, a sub-maximal dose of the cannabinoid agonist WIN 55 212-2, naltrexone (an ultra-low or a high dose) or a combination of WIN 55 212-2 and naltrexone doses. Tail-flick latencies were recorded for 3 h, at 10-min intervals for the first hour, and at 15-min intervals thereafter. Ultra-low dose naltrexone elevated WIN 55 212-2-induced tail flick thresholds without extending its duration of action. This enhancement was replicated in animals receiving intraperitoneal or intravenous injections. A high dose of naltrexone had no effect on WIN 55 212-2-induced tail flick latencies, but a high dose of the cannabinoid 1 receptor antagonist SR 141716 blocked the elevated tail-flick thresholds produced by WIN 55 212-2+ultra-low dose naltrexone. These data suggest a mechanism of cannabinoid-opioid interaction whereby activated opioid receptors that couple to Gs-proteins may attenuate cannabinoid-induced antinociception and/or motor functioning.

  7. Large-Scale Fluorescence Calcium-Imaging Methods for Studies of Long-Term Memory in Behaving Mammals

    PubMed Central

    Jercog, Pablo; Rogerson, Thomas; Schnitzer, Mark J.

    2016-01-01

    During long-term memory formation, cellular and molecular processes reshape how individual neurons respond to specific patterns of synaptic input. It remains poorly understood how such changes impact information processing across networks of mammalian neurons. To observe how networks encode, store, and retrieve information, neuroscientists must track the dynamics of large ensembles of individual cells in behaving animals, over timescales commensurate with long-term memory. Fluorescence Ca2+-imaging techniques can monitor hundreds of neurons in behaving mice, opening exciting avenues for studies of learning and memory at the network level. Genetically encoded Ca2+ indicators allow neurons to be targeted by genetic type or connectivity. Chronic animal preparations permit repeated imaging of neural Ca2+ dynamics over multiple weeks. Together, these capabilities should enable unprecedented analyses of how ensemble neural codes evolve throughout memory processing and provide new insights into how memories are organized in the brain. PMID:27048190

  8. Numerical Modelling of a Bidirectional Long Ring Raman Fiber Laser Dynamics

    NASA Astrophysics Data System (ADS)

    Sukhanov, S. V.; Melnikov, L. A.; Mazhirina, Yu A.

    2017-11-01

    The numerical model for the simulation of the dynamics of a bidirectional long ring Raman fiber laser is proposed. The model is based on the transport equations and Courant-Isaacson-Rees method. Different regimes of a bidirectional long ring Raman fiber laser and long time-domain realizations are investigated.

  9. In-flight sleep, pilot fatigue and Psychomotor Vigilance Task performance on ultra-long range versus long range flights.

    PubMed

    Gander, Philippa H; Signal, T Leigh; van den Berg, Margo J; Mulrine, Hannah M; Jay, Sarah M; Jim Mangie, Captain

    2013-12-01

    This study evaluated whether pilot fatigue was greater on ultra-long range (ULR) trips (flights >16 h on 10% of trips in a 90-day period) than on long range (LR) trips. The within-subjects design controlled for crew complement, pattern of in-flight breaks, flight direction and departure time. Thirty male Captains (mean age = 54.5 years) and 40 male First officers (mean age = 48.0 years) were monitored on commercial passenger flights (Boeing 777 aircraft). Sleep was monitored (actigraphy, duty/sleep diaries) from 3 days before the first study trip to 3 days after the second study trip. Karolinska Sleepiness Scale, Samn-Perelli fatigue ratings and a 5-min Psychomotor Vigilance Task were completed before, during and after every flight. Total sleep in the 24 h before outbound flights and before inbound flights after 2-day layovers was comparable for ULR and LR flights. All pilots slept on all flights. For each additional hour of flight time, they obtained an estimated additional 12.3 min of sleep. Estimated mean total sleep was longer on ULR flights (3 h 53 min) than LR flights (3 h 15 min; P(F) = 0.0004). Sleepiness ratings were lower and mean reaction speed was faster at the end of ULR flights. Findings suggest that additional in-flight sleep mitigated fatigue effectively on longer flights. Further research is needed to clarify the contributions to fatigue of in-flight sleep versus time awake at top of descent. The study design was limited to eastward outbound flights with two Captains and two First Officers. Caution must be exercised when extrapolating to different operations. © 2013 European Sleep Research Society.

  10. A non-inactivating high-voltage-activated two-pore Na+ channel that supports ultra-long action potentials and membrane bistability

    NASA Astrophysics Data System (ADS)

    Cang, Chunlei; Aranda, Kimberly; Ren, Dejian

    2014-09-01

    Action potentials (APs) are fundamental cellular electrical signals. The genesis of short APs lasting milliseconds is well understood. Ultra-long APs (ulAPs) lasting seconds to minutes also occur in eukaryotic organisms, but their biological functions and mechanisms of generation are largely unknown. Here, we identify TPC3, a previously uncharacterized member of the two-pore channel protein family, as a new voltage-gated Na+ channel (NaV) that generates ulAPs, and that establishes membrane potential bistability. Unlike the rapidly inactivating NaVs that generate short APs in neurons, TPC3 has a high activation threshold, activates slowly and does not inactivate—three properties that help generate long-lasting APs and guard the membrane against unintended perturbation. In amphibian oocytes, TPC3 forms a channel similar to channels induced by depolarization and sperm entry into eggs. TPC3 homologues are present in plants and animals, and they may be important for cellular processes and behaviours associated with prolonged membrane depolarization.

  11. Nanocluster building blocks of artificial square spin ice: Stray-field studies of thermal dynamics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pohlit, Merlin, E-mail: pohlit@physik.uni-frankfurt.de; Porrati, Fabrizio; Huth, Michael

    We present measurements of the thermal dynamics of a Co-based single building block of an artificial square spin ice fabricated by focused electron-beam-induced deposition. We employ micro-Hall magnetometry, an ultra-sensitive tool to study the stray field emanating from magnetic nanostructures, as a new technique to access the dynamical properties during the magnetization reversal of the spin-ice nanocluster. The obtained hysteresis loop exhibits distinct steps, displaying a reduction of their “coercive field” with increasing temperature. Therefore, thermally unstable states could be repetitively prepared by relatively simple temperature and field protocols allowing one to investigate the statistics of their switching behavior withinmore » experimentally accessible timescales. For a selected switching event, we find a strong reduction of the so-prepared states' “survival time” with increasing temperature and magnetic field. Besides the possibility to control the lifetime of selected switching events at will, we find evidence for a more complex behavior caused by the special spin ice arrangement of the macrospins, i.e., that the magnetic reversal statistically follows distinct “paths” most likely driven by thermal perturbation.« less

  12. From seconds to months: an overview of multi-scale dynamics of mobile telephone calls

    NASA Astrophysics Data System (ADS)

    Saramäki, Jari; Moro, Esteban

    2015-06-01

    Big Data on electronic records of social interactions allow approaching human behaviour and sociality from a quantitative point of view with unforeseen statistical power. Mobile telephone Call Detail Records (CDRs), automatically collected by telecom operators for billing purposes, have proven especially fruitful for understanding one-to-one communication patterns as well as the dynamics of social networks that are reflected in such patterns. We present an overview of empirical results on the multi-scale dynamics of social dynamics and networks inferred from mobile telephone calls. We begin with the shortest timescales and fastest dynamics, such as burstiness of call sequences between individuals, and "zoom out" towards longer temporal and larger structural scales, from temporal motifs formed by correlated calls between multiple individuals to long-term dynamics of social groups. We conclude this overview with a future outlook.

  13. Dynamic behavior of ultra large graphene-based membranes using electrothermal transduction

    NASA Astrophysics Data System (ADS)

    Al-mashaal, A. K.; Wood, G. S.; Torin, A.; Mastropaolo, E.; Newton, M. J.; Cheung, R.

    2017-12-01

    This letter reports an experimental study of an electrothermal actuator made from an ultra-large graphene-based bilayer thin film with a diameter to thickness aspect ratio of ˜10 000. Suspended thin films consisting of multilayer graphene and 350-500 nm-thick Poly(methyl methacrylate) have been transferred over circular cavities with a diameter of 3.5 mm. The use of bilayer materials with different mechanical and thermal properties results in thin film structures that can be induced to vibrate mechanically under the electrothermal transduction mechanism. The dynamic response of the bilayer has been investigated electrothermally by driving the structures with a combination of alternating current and direct current actuation voltages ( Va c and Vd c) and characterizing their resonant frequencies. It has been found that the bilayer thin film structure behaves as a membrane. In addition, the actuation configurations affect not only the amplitude of vibration but also the tuning of the resonant frequency of the vibrating membranes. The existence of Joule heating-induced tension lowers the mechanical stiffness of the membrane and hence shifts the resonant frequency downwards by -108187 ppm. A resonant frequency of 3.26 kHz with a vibration amplitude of 4.34 nm has been achieved for 350 nm-thick membranes under actuation voltages of 1 V of Va c and 8 V of Vd c.

  14. Simulation of heat storages and associated heat budgets in the Pacific Ocean: 2. Interdecadal timescale

    NASA Astrophysics Data System (ADS)

    Auad, Guillermo; Miller, Arthur J.; White, Warren B.

    1998-11-01

    tendency is nearly zero and the steady balance involves simply horizontal advection and the surface heat flux, which at these latitudes has a damping role in the model. An important finding of this study is the identification of two interdecadal timescales, roughly 10 and 20 years, both similar to those reported by other investigators in recent years. [Tourre et al., 1998; Latif and Barnett, 1994; Robertson, 1995; White et al, 1997; Gu and Philander, 1997; Jacobs et al., 1994]. The 20-year timescale is only present in diabatic heat budget components, while the 10-year timescale is present in both diabatic and adiabatic components. The 10-year timescale can also be seen in the surface heat flux time series, but it occurs in the ocean adiabatic components which demonstrates the importance of oceanic adjustment through Rossby wave dynamics on decadal timescales.

  15. Theoretical estimates of exposure timescales of protein binding sites on DNA regulated by nucleosome kinetics.

    PubMed

    Parmar, Jyotsana J; Das, Dibyendu; Padinhateeri, Ranjith

    2016-02-29

    It is being increasingly realized that nucleosome organization on DNA crucially regulates DNA-protein interactions and the resulting gene expression. While the spatial character of the nucleosome positioning on DNA has been experimentally and theoretically studied extensively, the temporal character is poorly understood. Accounting for ATPase activity and DNA-sequence effects on nucleosome kinetics, we develop a theoretical method to estimate the time of continuous exposure of binding sites of non-histone proteins (e.g. transcription factors and TATA binding proteins) along any genome. Applying the method to Saccharomyces cerevisiae, we show that the exposure timescales are determined by cooperative dynamics of multiple nucleosomes, and their behavior is often different from expectations based on static nucleosome occupancy. Examining exposure times in the promoters of GAL1 and PHO5, we show that our theoretical predictions are consistent with known experiments. We apply our method genome-wide and discover huge gene-to-gene variability of mean exposure times of TATA boxes and patches adjacent to TSS (+1 nucleosome region); the resulting timescale distributions have non-exponential tails. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

  16. Ultra-Long Time Dynamics of Contaminant Plume Mixing Induced by Transient Forcing Factors in Geologic Formations

    NASA Astrophysics Data System (ADS)

    Rajabi, F.; Battiato, I.

    2016-12-01

    Long term predictions of the impact of anthropogenic stressors on the environment is essential to reduce the risks associated with processes such as CO2 sequestration and nuclear waste storage in the subsurface. On the other hand, transient forcing factors (e.g. time-varying injection or pumping rate) with evolving heterogeneity of time scales spanning from days to years can influence transport phenomena at the pore scale. A comprehensive spatio-temporal prediction of reactive transport in porous media under time-dependent forcing factors for thousands of years requires the formulation of continuum scale models for time-averages. Yet, as every macroscopic model, time-averaged models can loose predictivity and accuracy when certain conditions are violated. This is true whenever lack of temporal and spatial scale separation occurs and it makes the continuum scale equation a poor assumption for the processes at the pore scale. In this work, we consider mass transport of a dissolved species undergoing a heterogeneous reaction and subject to time-varying boundary conditions in a periodic porous medium. By means of homogenization method and asymptotic expansion technique, we derive a macro-time continuum-scale equation as well as expressions for its effective properties. Our analysis demonstrates that the dynamics at the macro-scale is strongly influenced by the interplay between signal frequency at the boundary and transport processes at the pore level. In addition, we provide the conditions under which the space-time averaged equations accurately describe pore-scale processes. To validate our theoretical predictions, we consider a thin fracture with reacting walls and transient boundary conditions at the inlet. Our analysis shows a good agreement between numerical simulations and theoretical predictions. Furthermore, our numerical experiments show that mixing patterns of the contaminant plumes at the pore level strongly depend on the signal frequency.

  17. High-frequency microrheology reveals cytoskeleton dynamics in living cells

    NASA Astrophysics Data System (ADS)

    Rigato, Annafrancesca; Miyagi, Atsushi; Scheuring, Simon; Rico, Felix

    2017-08-01

    Living cells are viscoelastic materials, dominated by an elastic response on timescales longer than a millisecond. On shorter timescales, the dynamics of individual cytoskeleton filaments are expected to emerge, but active microrheology measurements on cells accessing this regime are scarce. Here, we develop high-frequency microrheology experiments to probe the viscoelastic response of living cells from 1 Hz to 100 kHz. We report the viscoelasticity of different cell types under cytoskeletal drug treatments. On previously inaccessible short timescales, cells exhibit rich viscoelastic responses that depend on the state of the cytoskeleton. Benign and malignant cancer cells revealed remarkably different scaling laws at high frequencies, providing a unique mechanical fingerprint. Microrheology over a wide dynamic range--up to the frequency characterizing the molecular components--provides a mechanistic understanding of cell mechanics.

  18. Functional domain motions in proteins on the ~1-100 ns timescale: comparison of neutron spin-echo spectroscopy of phosphoglycerate kinase with molecular-dynamics simulation.

    PubMed

    Smolin, N; Biehl, R; Kneller, G R; Richter, D; Smith, J C

    2012-03-07

    Protein function often requires large-scale domain motion. An exciting new development in the experimental characterization of domain motions in proteins is the application of neutron spin-echo spectroscopy (NSE). NSE directly probes coherent (i.e., pair correlated) scattering on the ~1-100 ns timescale. Here, we report on all-atom molecular-dynamics (MD) simulation of a protein, phosphoglycerate kinase, from which we calculate small-angle neutron scattering (SANS) and NSE scattering properties. The simulation-derived and experimental-solution SANS results are in excellent agreement. The contributions of translational and rotational whole-molecule diffusion to the simulation-derived NSE and potential problems in their estimation are examined. Principal component analysis identifies types of domain motion that dominate the internal motion's contribution to the NSE signal, with the largest being classic hinge bending. The associated free-energy profiles are quasiharmonic and the frictional properties correspond to highly overdamped motion. The amplitudes of the motions derived by MD are smaller than those derived from the experimental analysis, and possible reasons for this difference are discussed. The MD results confirm that a significant component of the NSE arises from internal dynamics. They also demonstrate that the combination of NSE with MD is potentially useful for determining the forms, potentials of mean force, and time dependence of functional domain motions in proteins. Copyright © 2012 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  19. Ultra-thin smart acoustic metasurface for low-frequency sound insulation

    NASA Astrophysics Data System (ADS)

    Zhang, Hao; Xiao, Yong; Wen, Jihong; Yu, Dianlong; Wen, Xisen

    2016-04-01

    Insulating low-frequency sound is a conventional challenge due to the high areal mass required by mass law. In this letter, we propose a smart acoustic metasurface consisting of an ultra-thin aluminum foil bonded with piezoelectric resonators. Numerical and experimental results show that the metasurface can break the conventional mass law of sound insulation by 30 dB in the low frequency regime (<1000 Hz), with an ultra-light areal mass density (<1.6 kg/m2) and an ultra-thin thickness (1000 times smaller than the operating wavelength). The underlying physical mechanism of such extraordinary sound insulation performance is attributed to the infinite effective dynamic mass density produced by the smart resonators. It is also demonstrated that the excellent sound insulation property can be conveniently tuned by simply adjusting the external circuits instead of modifying the structure of the metasurface.

  20. All-optical flip-flops based on dynamic Brillouin gratings in fibers.

    PubMed

    Soto, Marcelo A; Denisov, Andrey; Angulo-Vinuesa, Xabier; Martin-Lopez, Sonia; Thévenaz, Luc; Gonzalez-Herraez, Miguel

    2017-07-01

    A method to generate an all-optical flip-flop is proposed and experimentally demonstrated based on dynamic Brillouin gratings (DBGs) in polarization maintaining fibers. In a fiber with sufficiently uniform birefringence, this flip-flop can provide extremely long storage times and ultra-wide bandwidth. The experimental results demonstrate an all-optical flip-flop operation using phase-modulated pulses of 300 ps and a 1 m long DBG. This has led to a time-bandwidth product of ∼30, being in this proof-of-concept setup mainly limited by the relatively low bandwidth of the used pulses and the short fiber length.

  1. Dynamical Imaging with Interferometry

    NASA Astrophysics Data System (ADS)

    Johnson, Michael D.; Bouman, Katherine L.; Blackburn, Lindy; Chael, Andrew A.; Rosen, Julian; Shiokawa, Hotaka; Roelofs, Freek; Akiyama, Kazunori; Fish, Vincent L.; Doeleman, Sheperd S.

    2017-12-01

    By linking widely separated radio dishes, the technique of very long baseline interferometry (VLBI) can greatly enhance angular resolution in radio astronomy. However, at any given moment, a VLBI array only sparsely samples the information necessary to form an image. Conventional imaging techniques partially overcome this limitation by making the assumption that the observed cosmic source structure does not evolve over the duration of an observation, which enables VLBI networks to accumulate information as Earth rotates and changes the projected array geometry. Although this assumption is appropriate for nearly all VLBI, it is almost certainly violated for submillimeter observations of the Galactic center supermassive black hole, Sagittarius A* (Sgr A*), which has a gravitational timescale of only ∼ 20 s and exhibits intrahour variability. To address this challenge, we develop several techniques to reconstruct dynamical images (“movies”) from interferometric data. Our techniques are applicable to both single-epoch and multiepoch variability studies, and they are suitable for exploring many different physical processes including flaring regions, stable images with small time-dependent perturbations, steady accretion dynamics, or kinematics of relativistic jets. Moreover, dynamical imaging can be used to estimate time-averaged images from time-variable data, eliminating many spurious image artifacts that arise when using standard imaging methods. We demonstrate the effectiveness of our techniques using synthetic observations of simulated black hole systems and 7 mm Very Long Baseline Array observations of M87, and we show that dynamical imaging is feasible for Event Horizon Telescope observations of Sgr A*.

  2. Two approaches to timescale modeling for proxy series with chronological errors.

    NASA Astrophysics Data System (ADS)

    Divine, Dmitry; Godtliebsen, Fred

    2010-05-01

    A substantial part of proxy series used in paleoclimate research has chronological uncertainties. Any constructed timescale is therefore only an estimate of the true, but unknown timescale. An accurate assessment of the timing of events in the paleoproxy series and networks, as well as the use of proxy-based paleoclimate reconstructions in GCM model scoring experiments, requires the effect of these errors to be properly taken into account. We consider two types of the timescale error models corresponding to the two basic approaches to construction of the (depth-) age scale in a proxy series. Typically, a chronological control of a proxy series stemming from all types of marine and terrestrial sedimentary archives is based on the use of 14C dates, reference horizons or their combination. Depending on the prevalent origin of the available fix points (age markers) the following approaches to timescale modeling are proposed. 1) 14C dates. The algorithm uses Markov-chain Monte Carlo sampling technique to generate the ordered set of perturbed age markers. Proceeding sequentially from the youngest to the oldest fixpoint, the sampler draws random numbers from the age distribution of each individual 14C date. Every following perturbed age marker is generated such that condition of no age reversal is fulfilled. The relevant regression model is then applied to construct a simulated timescale. 2) Reference horizons (f. ex. volcanic or dust layers, T bomb peak) generally provide absolutely dated fixpoints. Due to a natural variability in sedimentation (accumulation) rate, however, the dating uncertainty in the interpolated timescale tends to grow together with a span to the nearest fixpoint. The (accumulation, sedimentation) process associated with formation of a proxy series is modelled using stochastic Levy process. The respective increments for the process are drawn from the log-normal distribution with the mean/variance ratio prescribed as a site(proxy)- dependent external

  3. Spatial Covariability of Temperature and Hydroclimate as a Function of Timescale During the Common Era

    NASA Astrophysics Data System (ADS)

    McKay, N.

    2017-12-01

    As timescale increases from years to centuries, the spatial scale of covariability in the climate system is hypothesized to increase as well. Covarying spatial scales are larger for temperature than for hydroclimate, however, both aspects of the climate system show systematic changes on large-spatial scales on orbital to tectonic timescales. The extent to which this phenomenon is evident in temperature and hydroclimate at centennial timescales is largely unknown. Recent syntheses of multidecadal to century-scale variability in hydroclimate during the past 2k in the Arctic, North America, and Australasia show little spatial covariability in hydroclimate during the Common Era. To determine 1) the evidence for systematic relationships between the spatial scale of climate covariability as a function of timescale, and 2) whether century-scale hydroclimate variability deviates from the relationship between spatial covariability and timescale, we quantify this phenomenon during the Common Era by calculating the e-folding distance in large instrumental and paleoclimate datasets. We calculate this metric of spatial covariability, at different timescales (1, 10 and 100-yr), for a large network of temperature and precipitation observations from the Global Historical Climatology Network (n=2447), from v2.0.0 of the PAGES2k temperature database (n=692), and from moisture-sensitive paleoclimate records North America, the Arctic, and the Iso2k project (n = 328). Initial results support the hypothesis that the spatial scale of covariability is larger for temperature, than for precipitation or paleoclimate hydroclimate indicators. Spatially, e-folding distances for temperature are largest at low latitudes and over the ocean. Both instrumental and proxy temperature data show clear evidence for increasing spatial extent as a function of timescale, but this phenomenon is very weak in the hydroclimate data analyzed here. In the proxy hydroclimate data, which are predominantly

  4. Expression Differentiation Is Constrained to Low-Expression Proteins over Ecological Timescales

    PubMed Central

    Margres, Mark J.; Wray, Kenneth P.; Seavy, Margaret; McGivern, James J.; Herrera, Nathanael D.; Rokyta, Darin R.

    2016-01-01

    Protein expression level is one of the strongest predictors of protein sequence evolutionary rate, with high-expression protein sequences evolving at slower rates than low-expression protein sequences largely because of constraints on protein folding and function. Expression evolutionary rates also have been shown to be negatively correlated with expression level across human and mouse orthologs over relatively long divergence times (i.e., ∼100 million years). Long-term evolutionary patterns, however, often cannot be extrapolated to microevolutionary processes (and vice versa), and whether this relationship holds for traits evolving under directional selection within a single species over ecological timescales (i.e., <5000 years) is unknown and not necessarily expected. Expression is a metabolically costly process, and the expression level of a particular protein is predicted to be a tradeoff between the benefit of its function and the costs of its expression. Selection should drive the expression level of all proteins close to values that maximize fitness, particularly for high-expression proteins because of the increased energetic cost of production. Therefore, stabilizing selection may reduce the amount of standing expression variation for high-expression proteins, and in combination with physiological constraints that may place an upper bound on the range of beneficial expression variation, these constraints could severely limit the availability of beneficial expression variants. To determine whether rapid-expression evolution was restricted to low-expression proteins owing to these constraints on highly expressed proteins over ecological timescales, we compared venom protein expression levels across mainland and island populations for three species of pit vipers. We detected significant differentiation in protein expression levels in two of the three species and found that rapid-expression differentiation was restricted to low-expression proteins. Our

  5. Integrating atomistic molecular dynamics simulations, experiments, and network analysis to study protein dynamics: strength in unity.

    PubMed

    Papaleo, Elena

    2015-01-01

    In the last years, we have been observing remarkable improvements in the field of protein dynamics. Indeed, we can now study protein dynamics in atomistic details over several timescales with a rich portfolio of experimental and computational techniques. On one side, this provides us with the possibility to validate simulation methods and physical models against a broad range of experimental observables. On the other side, it also allows a complementary and comprehensive view on protein structure and dynamics. What is needed now is a better understanding of the link between the dynamic properties that we observe and the functional properties of these important cellular machines. To make progresses in this direction, we need to improve the physical models used to describe proteins and solvent in molecular dynamics, as well as to strengthen the integration of experiments and simulations to overcome their own limitations. Moreover, now that we have the means to study protein dynamics in great details, we need new tools to understand the information embedded in the protein ensembles and in their dynamic signature. With this aim in mind, we should enrich the current tools for analysis of biomolecular simulations with attention to the effects that can be propagated over long distances and are often associated to important biological functions. In this context, approaches inspired by network analysis can make an important contribution to the analysis of molecular dynamics simulations.

  6. Indian monsoon variability on millennial-orbital timescales

    PubMed Central

    Kathayat, Gayatri; Cheng, Hai; Sinha, Ashish; Spötl, Christoph; Edwards, R. Lawrence; Zhang, Haiwei; Li, Xianglei; Yi, Liang; Ning, Youfeng; Cai, Yanjun; Lui, Weiguo Lui; Breitenbach, Sebastian F. M.

    2016-01-01

    The Indian summer monsoon (ISM) monsoon is critical to billions of people living in the region. Yet, significant debates remain on primary ISM drivers on millennial-orbital timescales. Here, we use speleothem oxygen isotope (δ18O) data from Bittoo cave, Northern India to reconstruct ISM variability over the past 280,000 years. We find strong coherence between North Indian and Chinese speleothem δ18O records from the East Asian monsoon domain, suggesting that both Asian monsoon subsystems exhibit a coupled response to changes in Northern Hemisphere summer insolation (NHSI) without significant temporal lags, supporting the view that the tropical-subtropical monsoon variability is driven directly by precession-induced changes in NHSI. Comparisons of the North Indian record with both Antarctic ice core and sea-surface temperature records from the southern Indian Ocean over the last glacial period do not suggest a dominant role of Southern Hemisphere climate processes in regulating the ISM variability on millennial-orbital timescales. PMID:27071753

  7. Indian monsoon variability on millennial-orbital timescales.

    PubMed

    Kathayat, Gayatri; Cheng, Hai; Sinha, Ashish; Spötl, Christoph; Edwards, R Lawrence; Zhang, Haiwei; Li, Xianglei; Yi, Liang; Ning, Youfeng; Cai, Yanjun; Lui, Weiguo Lui; Breitenbach, Sebastian F M

    2016-04-13

    The Indian summer monsoon (ISM) monsoon is critical to billions of people living in the region. Yet, significant debates remain on primary ISM drivers on millennial-orbital timescales. Here, we use speleothem oxygen isotope (δ(18)O) data from Bittoo cave, Northern India to reconstruct ISM variability over the past 280,000 years. We find strong coherence between North Indian and Chinese speleothem δ(18)O records from the East Asian monsoon domain, suggesting that both Asian monsoon subsystems exhibit a coupled response to changes in Northern Hemisphere summer insolation (NHSI) without significant temporal lags, supporting the view that the tropical-subtropical monsoon variability is driven directly by precession-induced changes in NHSI. Comparisons of the North Indian record with both Antarctic ice core and sea-surface temperature records from the southern Indian Ocean over the last glacial period do not suggest a dominant role of Southern Hemisphere climate processes in regulating the ISM variability on millennial-orbital timescales.

  8. Stability of Sexual Attractions Across Different Timescales: The Roles of Bisexuality and Gender.

    PubMed

    Diamond, Lisa M; Dickenson, Janna A; Blair, Karen L

    2017-01-01

    We examined the stability of same-sex and other-sex attractions among 294 heterosexual, lesbian, gay, and bisexual men and women between the ages of 18 and 40 years. Participants used online daily diaries to report the intensity of each day's strongest same-sex and other-sex attraction, and they also reported on changes they recalled experiencing in their attractions since adolescence. We used multilevel dynamical systems models to examine individual differences in the stability of daily attractions (stability, in these models, denotes the tendency for attractions to "self-correct" toward a person-specific setpoint over time). Women's attractions showed less day-to-day stability than men's, consistent with the notion of female sexual fluidity (i.e., heightened erotic sensitivity to situational and contextual influences). Yet, women did not recollect larger post-adolescent changes in sexual attractions than did men, and larger recollected post-adolescent changes did not predict lower day-to-day stability in the sample as a whole. Bisexually attracted individuals recollected larger post-adolescent changes in their attractions, and they showed lower day-to-day stability in attractions to their "less-preferred" gender, compared to individuals with exclusive same-sex or exclusive other-sex attractions. Our results suggest that both gender and bisexuality have independent influences on sexual fluidity, but these influences vary across short versus long timescales, and they also differ for attractions to one's "more-preferred" versus "less-preferred" gender.

  9. Ultrafast photodimerization dynamics in α-cyano-4-hydroxycinnamic and sinapinic acid crystals

    NASA Astrophysics Data System (ADS)

    Hoyer, Theo; Tuszynski, Wilfried; Lienau, Christoph

    2007-07-01

    We report a sub-picosecond time-resolved fluorescence spectroscopic study of different cinnamic acid crystals, model systems for solid-state photodimerization reactions. For α-cyano-4-hydroxycinnamic acid (α-CHC), we identify the emission spectra of both monomers and dimers, allowing us to directly probe the photoinduced dynamics of both species. The dimerization occurs on a timescale of 10 ps and results in a long-lived dimer product, stable for hours. For sinapinic acid, we find an extremely fast, sub-picosecond dimerization reaction and a short-lived dimer. This first sub-picosecond time-resolved dimerization study in cinnamic acid crystals provides a new basis for relating their structural properties and microscopic reaction dynamics.

  10. Monitoring and Managing Cabin Crew Sleep and Fatigue During an Ultra-Long Range Trip.

    PubMed

    van den Berg, Margo J; Signal, T Leigh; Mulrine, Hannah M; Smith, Alexander A T; Gander, Philippa H; Serfontein, Wynand

    2015-08-01

    The aims of this study were to monitor cabin crew fatigue, sleep, and performance on an ultra-long range (ULR) trip and to evaluate the appropriateness of applying data collection methods developed for flight crew to cabin crew operations under a fatigue risk management system (FRMS). Prior to, throughout, and following the ULR trip (outbound flight ULR; mean layover duration=52.6 h; inbound flight long range), 55 cabin crew (29 women; mean age 36.5 yr; 25 men; mean age 36.6 yr; one missing data) completed a sleep/duty diary and wore an actigraph. Across each flight, crewmembers rated their fatigue (Samn-Perelli Crew Status Check) and sleepiness (Karolinska Sleepiness Scale) and completed a 5-min Psychomotor Vigilance Task (PVT) at key times. Of crewmembers approached, 73% (N=134) agreed to participate and 41% (N=55) provided data of suitable quality for analysis. In the 24 h before departure, sleep averaged 7.0 h and 40% took a preflight nap. All crewmembers slept in flight (mean total sleep time=3.6 h outbound, 2.9 h inbound). Sleepiness and fatigue were lower, and performance better, on the longer outbound flight than on the inbound flight. Post-trip, crewmembers slept more on day 1 (mean=7.9 h) compared to baseline days, but there was no difference from day 2 onwards. The present study demonstrates that cabin crew fatigue can be managed effectively on a ULR flight and that FRMS data collection is feasible for cabin crew, but operational differences between cabin crew and flight crew need to be considered.

  11. VI-band follow-up observations of ultra-long-period Cepheid candidates in M31

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ngeow, Chow-Choong; Yang, Michael Ting-Chang; Lin, Chi-Sheng

    2015-02-01

    The ultra-long-period Cepheids (ULPCs) are classical Cepheids with pulsation periods exceeding ≈80 days. The intrinsic brightness of ULPCs are ∼1 to ∼3 mag brighter than their shorter period counterparts. This makes them attractive in future distance scale work to derive distances beyond the limit set by the shorter period Cepheids. We have initiated a program to search for ULPCs in M31, using the single-band data taken from the Palomar Transient Factory, and identified eight possible candidates. In this work, we presented the VI-band follow-up observations of these eight candidates. Based on our VI-band light curves of these candidates and theirmore » locations in the color–magnitude diagram and the Period–Wesenheit diagram, we verify two candidates as being truly ULPCs. The six other candidates are most likely other kinds of long-period variables. With the two confirmed M31 ULPCs, we tested the applicability of ULPCs in distance scale work by deriving the distance modulus of M31. It was found to be μ{sub M31,ULPC}=24.30±0.76 mag. The large error in the derived distance modulus, together with the large intrinsic dispersion of the Period–Wesenheit (PW) relation and the small number of ULPCs in a given host galaxy, means that the question of the suitability of ULPCs as standard candles is still open. Further work is needed to enlarge the sample of calibrating ULPCs and reduce the intrinsic dispersion of the PW relation before re-considering ULPCs as suitable distance indicators.« less

  12. Dynamical Timescale of Pre-collapse Evolution Inferred from Chemical Distribution in the Taurus Molecular Cloud-1 (TMC-1) Filament

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Choi, Yunhee; Lee, Jeong-Eun; Bourke, Tyler L.

    We present observations and analyses of the low-mass star-forming region, Taurus Molecular Cloud-1 (TMC-1). CS ( J = 2–1)/N{sub 2}H{sup +} ( J = 1–0) and C{sup 17}O ( J = 2–1)/C{sup 18}O ( J = 2–1) were observed with the Five College Radio Astronomy Observatory and the Seoul Radio Astronomy Observatory, respectively. In addition, Spitzer infrared data and 1.2 mm continuum data observed with Max-Planck Millimetre Bolometer are used. We also perform chemical modeling to investigate the relative molecular distributions of the TMC-1 filament. Based on Spitzer observations, there is no young stellar object along the TMC-1 filament, while five Classmore » II and one Class I young stellar objects are identified outside the filament. The comparison between column densities calculated from dust continuum and C{sup 17}O 2–1 line emission shows that CO is depleted much more significantly in the ammonia peak than in the cyanopolyyne peak, while the column densities calculated from the dust continuum are similar at the two peaks. N{sub 2}H{sup +} is not depleted much in either peak. According to our chemical calculation, the differential chemical distribution in the two peaks can be explained by different timescales required to reach the same density, i.e., by different dynamical processes.« less

  13. Real-time modulated nanoparticle separation with an ultra-large dynamic range.

    PubMed

    Zeming, Kerwin Kwek; Thakor, Nitish V; Zhang, Yong; Chen, Chia-Hung

    2016-01-07

    Nanoparticles exhibit size-dependent properties which make size-selective purification of proteins, DNA or synthetic nanoparticles essential for bio-analytics, clinical medicine, nano-plasmonics and nano-material sciences. Current purification methods of centrifugation, column chromatography and continuous-flow techniques suffer from particle aggregation, multi-stage process, complex setups and necessary nanofabrication. These increase process costs and time, reduce efficiency and limit dynamic range. Here, we achieve an unprecedented real-time nanoparticle separation (51-1500 nm) using a large-pore (2 μm) deterministic lateral displacement (DLD) device. No external force fields or nanofabrication are required. Instead, we investigated innate long-range electrostatic influences on nanoparticles within a fluid medium at different NaCl ionic concentrations. In this study we account for the electrostatic forces beyond Debye length and showed that they cannot be assumed as negligible especially for precise nanoparticle separation methods such as DLD. Our findings have enabled us to develop a model to simultaneously quantify and modulate the electrostatic force interactions between nanoparticle and micropore. By simply controlling buffer solutions, we achieve dynamic nanoparticle size separation on a single device with a rapid response time (<20 s) and an enlarged dynamic range (>1200%), outperforming standard benchtop centrifuge systems. This novel method and model combines device simplicity, isolation precision and dynamic flexibility, opening opportunities for high-throughput applications in nano-separation for industrial and biological applications.

  14. Methods and Costs to Achieve Ultra Reliable Life Support

    NASA Technical Reports Server (NTRS)

    Jones, Harry W.

    2012-01-01

    A published Mars mission is used to explore the methods and costs to achieve ultra reliable life support. The Mars mission and its recycling life support design are described. The life support systems were made triply redundant, implying that each individual system will have fairly good reliability. Ultra reliable life support is needed for Mars and other long, distant missions. Current systems apparently have insufficient reliability. The life cycle cost of the Mars life support system is estimated. Reliability can be increased by improving the intrinsic system reliability, adding spare parts, or by providing technically diverse redundant systems. The costs of these approaches are estimated. Adding spares is least costly but may be defeated by common cause failures. Using two technically diverse systems is effective but doubles the life cycle cost. Achieving ultra reliability is worth its high cost because the penalty for failure is very high.

  15. CONSTRAINTS ON MACHO DARK MATTER FROM COMPACT STELLAR SYSTEMS IN ULTRA-FAINT DWARF GALAXIES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brandt, Timothy D.

    2016-06-20

    I show that a recently discovered star cluster near the center of the ultra-faint dwarf galaxy Eridanus II provides strong constraints on massive compact halo objects (MACHOs) of ≳5 M {sub ⊙} as the main component of dark matter. MACHO dark matter will dynamically heat the cluster, driving it to larger sizes and higher velocity dispersions until it dissolves into its host galaxy. The stars in compact ultra-faint dwarf galaxies themselves will be subject to the same dynamical heating; the survival of at least 10 such galaxies places independent limits on MACHO dark matter of masses ≳10 M {sub ⊙}.more » Both Eri II’s cluster and the compact ultra-faint dwarfs are characterized by stellar masses of just a few thousand M {sub ⊙} and half-light radii of 13 pc (for the cluster) and ∼30 pc (for the ultra-faint dwarfs). These systems close the ∼20–100 M {sub ⊙} window of allowed MACHO dark matter and combine with existing constraints from microlensing, wide binaries, and disk kinematics to rule out dark matter composed entirely of MACHOs from ∼10{sup −7} M {sub ⊙} up to arbitrarily high masses.« less

  16. The Effects of Ultra-Long-Range Flights on the Alertness and Performance of Aviators

    NASA Technical Reports Server (NTRS)

    Caldwell, John A.; Mallis, Melissa M.; Colletti, Laura M.; Oyung, Raymond L.; Brandt, Summer L.; Arsintescu, Lucia; DeRoshia, Charlie W.; Reduta-Rojas, Dinah D.; Chapman, Patrick M.

    2006-01-01

    This investigation assessed the impact of ultra-long-range (ULR) simulator flights, departing either in the morning or late evening, on the alertness and performance of 17 commercial aviators. Immediately prior to and throughout each flight, alertness and performance were assessed via a computerized test of sustained attention, subjective questionnaires, and "hand-flying" tasks. There were fatigue-related effects on the majority of assessments, and the nature of these effects was consistent across the vigilance and self-report measures. However, the operational "hand-flying" manuevers proved insensitive to the impact of fatigue probably due to procedural factors. Regardless, the results of the present study suggest that fatigue associated with prolonged wakefulness in ULR flight operations will interact with flight schedules due to circadian and homeostatic influences. In this study, the pilots departing at night were at a greater initial disadvantage (during cruise) than pilots who departed earlier in the day; whereas those who departed earlier tended to be most impaired towards the end of the flight prior to landing. In real-world operations, airlines should consider the ramifications of flight schedules and what is known about human sleep and circadian rhythms to optimize safety.

  17. SMUVS: Spitzer Matching survey of the UltraVISTA ultra-deep Stripes

    NASA Astrophysics Data System (ADS)

    Caputi, Karina; Ashby, Matthew; Fazio, Giovanni; Huang, Jiasheng; Dunlop, James; Franx, Marijn; Le Fevre, Olivier; Fynbo, Johan; McCracken, Henry; Milvang-Jensen, Bo; Muzzin, Adam; Ilbert, Olivier; Somerville, Rachel; Wechsler, Risa; Behroozi, Peter; Lu, Yu

    2014-12-01

    We request 2026.5 hours to homogenize the matching ultra-deep IRAC data of the UltraVISTA ultra-deep stripes, producing a final area of ~0.6 square degrees with the deepest near- and mid-IR coverage existing in any such large area of the sky (H, Ks, [3.6], [4.5] ~ 25.3-26.1 AB mag; 5 sigma). The UltraVISTA ultra-deep stripes are contained within the larger COSMOS field, which has a rich collection of multi-wavelength, ancillary data, making it ideal to study different aspects of galaxy evolution with high statistical significance and excellent redshift accuracy. The UltraVISTA ultra-deep stripes are the region of the COSMOS field where these studies can be pushed to the highest redshifts, but securely identifying high-z galaxies, and determining their stellar masses, will only be possible if ultra-deep mid-IR data are available. Our IRAC observations will allow us to: 1) extend the galaxy stellar mass function at redshifts z=3 to z=5 to the intermediate mass regime (M~5x10^9-10^10 Msun), which is critical to constrain galaxy formation models; 2) gain a factor of six in the area where it is possible to effectively search for z>=6 galaxies and study their properties; 3) measure, for the first time, the large-scale structure traced by an unbiased galaxy sample at z=5 to z=7, and make the link to their host dark matter haloes. This cannot be done in any other field of the sky, as the UltraVISTA ultra-deep stripes form a quasi-contiguous, regular-shape field, which has a unique combination of large area and photometric depth. 4) provide a unique resource for the selection of secure z>5 targets for JWST and ALMA follow up. Our observations will have an enormous legacy value which amply justifies this new observing-time investment in the COSMOS field. Spitzer cannot miss this unique opportunity to open up a large 0.6 square-degree window to the early Universe.

  18. Evaluation of electrical conductivity and equations of state of non-ideal plasma through microsecond timescale underwater electrical wire explosion

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sheftman, D.; Krasik, Ya. E.

    2011-09-15

    Experimental and simulation results of underwater electrical Cu, Al, and W wire explosions in the microsecond timescale are presented. It was shown that the electrical conductivity results for Cu and Al agree well with modified Lee-More and quantum molecular dynamic models for temperatures above 10 kK. The equation of state (EOS) values based on SESAME tables for Cu and Al were slightly modified for intermediate temperatures in order to obtain fitting between experimental and simulated exploding wire radial expansion. Also, it was shown that the electrical conductivity results and the EOS evaluation differ significantly from the results obtained in nanosecondmore » timescale experiments. Finally, it was found that underwater electrical W wire explosion is characterized by the appearance of non-uniformities along the z-axis of the wire. This phenomena adds uncertainty to the possibility of applying this type of experiments for evaluation of the electrical conductivity and EOS of W.« less

  19. Ultra-rapid earth rotation determination with VLBI during CONT11 and CONT14

    NASA Astrophysics Data System (ADS)

    Haas, Rüdiger; Hobiger, Thomas; Kurihara, Shinobu; Hara, Tetsuya

    2015-08-01

    In 2007 the Geospatial Information Authority of Japan (GSI) and the Onsala Space Observatory (OSO) started a collaboration project aiming at determining the earth rotation angle, usually expressed as UT1-UTC, in near real-time. In the beginning of this project dedicated one hour long one-baseline experiments were observed periodically using the VLBI stations Onsala (Sweden) and Tsukuba (Japan). The strategy is that the observed VLBI data are sent in real-time via the international optical fibre backbone to the correlator at Tsukuba where the data are correlated with a software correlator and analyzed in near-real time with the c5++ VLBI data analysis software, thus producing UT1-UTC results with very low latency. The latency between the observation at the stations and the determination of UT1-UTC is on the order of a few minutes, thus we can talk about an ultra-rapid determination of UT1-UTC. An offline version of this strategy was adopted in 2009 for the regular VLBI intensive series INT-2, organized by the International VLBI Service for Geodesy and Astrometry (IVS), that involves Wettzell (Germany) and Tsukuba. Since March 2010 the INT-2 is using real-time e-transfer, too, and since June 2010 also automated analysis. Starting in 2009 the ultra-rapid approach was applied to regular 24 hour long IVS VLBI-sessions that involve Tsukuba and Onsala, so that ultra-rapid UT1-UTC results can be produced already during ongoing VLBI-sessions. This strategy was successfully operated during the 15 days long continuous VLBI campaigns CONT11 and CONT14. In this presentation we give an overview of the ultra-rapid concept, present the results derived during CONT11 and CONT14, and compare these ultra-rapid results to results derived from post-processing

  20. Ultra-rapid earth rotation determination with VLBI during CONT11 and CONT14

    NASA Astrophysics Data System (ADS)

    Haas, Rüdiger; Hobiger, Thomas; Kurihara, Shinobu; Hara, Tetsuya

    2016-04-01

    In 2007 the Geospatial Information Authority of Japan (GSI) and the Onsala Space Observatory (OSO) started a collaboration project aiming at determining the earth rotation angle, usually expressed as UT1-UTC, in near real-time. In the beginning of this project dedicated one hour long one-baseline experiments were observed periodically using the VLBI stations Onsala (Sweden) and Tsukuba (Japan). The strategy is that the observed VLBI data are sent in real-time via the international optical fibre backbone to the correlator at Tsukuba where the data are correlated with a software correlator and analyzed in near-real time with the c5++ VLBI data analysis software, thus producing UT1-UTC results with very low latency. The latency between the observation at the stations and the determination of UT1-UTC is on the order of a few minutes, thus we can talk about an ultra-rapid determination of UT1-UTC. An offline version of this strategy was adopted in 2009 for the regular VLBI intensive series INT-2, organized by the International VLBI Service for Geodesy and Astrometry (IVS), that involves Wettzell (Germany) and Tsukuba. Since March 2010 the INT-2 is using real-time e-transfer, too, and since June 2010 also automated analysis. Starting in 2009 the ultra-rapid approach was applied to regular 24 hour long IVS VLBI-sessions that involve Tsukuba and Onsala, so that ultra-rapid UT1-UTC results can be produced already during ongoing VLBI-sessions. This strategy was successfully operated during the 15 days long continuous VLBI campaigns CONT11 and CONT14. In this presentation we give an overview of the ultra-rapid concept, present the results derived during CONT11 and CONT14, and compare these ultra-rapid results to results derived from post-processing.

  1. Density and temperature characterization of long-scale length, near-critical density controlled plasma produced from ultra-low density plastic foam

    PubMed Central

    Chen, S. N.; Iwawaki, T.; Morita, K.; Antici, P.; Baton, S. D.; Filippi, F.; Habara, H.; Nakatsutsumi, M.; Nicolaï , P.; Nazarov, W.; Rousseaux, C.; Starodubstev, M.; Tanaka, K. A.; Fuchs, J.

    2016-01-01

    The ability to produce long-scale length (i.e. millimeter scale-length), homogeneous plasmas is of interest in studying a wide range of fundamental plasma processes. We present here a validated experimental platform to create and diagnose uniform plasmas with a density close or above the critical density. The target consists of a polyimide tube filled with an ultra low-density plastic foam where it was heated by x-rays, produced by a long pulse laser irradiating a copper foil placed at one end of the tube. The density and temperature of the ionized foam was retrieved by using x-ray radiography and proton radiography was used to verify the uniformity of the plasma. Plasma temperatures of 5–10 eV and densities around 1021 cm−3 are measured. This well-characterized platform of uniform density and temperature plasma is of interest for experiments using large-scale laser platforms conducting High Energy Density Physics investigations. PMID:26923471

  2. The Arctic Predictability and Prediction on Seasonal-to-Interannual TimEscales (APPOSITE) data set

    NASA Astrophysics Data System (ADS)

    Day, J. J.; Tietsche, S.; Collins, M.; Goessling, H. F.; Guemas, V.; Guillory, A.; Hurlin, W. J.; Ishii, M.; Keeley, S. P. E.; Matei, D.; Msadek, R.; Sigmond, M.; Tatebe, H.; Hawkins, E.

    2015-10-01

    Recent decades have seen significant developments in seasonal-to-interannual timescale climate prediction capabilities. However, until recently the potential of such systems to predict Arctic climate had not been assessed. This paper describes a multi-model predictability experiment which was run as part of the Arctic Predictability and Prediction On Seasonal to Inter-annual Timescales (APPOSITE) project. The main goal of APPOSITE was to quantify the timescales on which Arctic climate is predictable. In order to achieve this, a coordinated set of idealised initial-value predictability experiments, with seven general circulation models, was conducted. This was the first model intercomparison project designed to quantify the predictability of Arctic climate on seasonal to inter-annual timescales. Here we present a description of the archived data set (which is available at the British Atmospheric Data Centre) and an update of the project's results. Although designed to address Arctic predictability, this data set could also be used to assess the predictability of other regions and modes of climate variability on these timescales, such as the El Niño Southern Oscillation.

  3. Evidence of strategic periodicities in collective conflict dynamics.

    PubMed

    Dedeo, Simon; Krakauer, David; Flack, Jessica

    2011-09-07

    We analyse the timescales of conflict decision-making in a primate society. We present evidence for multiple, periodic timescales associated with social decision-making and behavioural patterns. We demonstrate the existence of periodicities that are not directly coupled to environmental cycles or known ultraridian mechanisms. Among specific biological and socially defined demographic classes, periodicities span timescales between hours and days. Our results indicate that these periodicities are not driven by exogenous or internal regularities but are instead driven by strategic responses to social interaction patterns. Analyses also reveal that a class of individuals, playing a critical functional role, policing, have a signature timescale of the order of 1 h. We propose a classification of behavioural timescales analogous to those of the nervous system, with high frequency, or α-scale, behaviour occurring on hour-long scales, through to multi-hour, or β-scale, behaviour, and, finally γ periodicities observed on a timescale of days.

  4. Multivariate machine learning distinguishes cross-network dynamic functional connectivity patterns in state and trait neuropathic pain.

    PubMed

    Cheng, J C; Rogachov, A; Hemington, K S; Kucyi, A; Bosma, R L; Lindquist, M A; Inman, R D; Davis, K D

    2018-04-26

    Communication within the brain is dynamic. Chronic pain can also be dynamic, with varying intensities experienced over time. Little is known of how brain dynamics are disrupted in chronic pain, or relates to patients' pain assessed at various time-scales (e.g., short-term state versus long-term trait). Patients experience pain "traits" indicative of their general condition, but also pain "states" that vary day to day. Here, we used network-based multivariate machine learning to determine how patterns in dynamic and static brain communication are related to different characteristics and timescales of chronic pain. Our models were based on resting state dynamic and static functional connectivity (dFC, sFC) in patients with chronic neuropathic pain (NP) or non-NP. The most prominent networks in the models were the default mode, salience, and executive control networks. We also found that cross-network measures of dFC rather than sFC were better associated with patients' pain, but only in those with NP features. These associations were also more highly and widely associated with measures of trait rather than state pain. Furthermore, greater dynamic connectivity with executive control networks was associated with milder neuropathic pain, but greater dynamic connectivity with limbic networks was associated greater neuropathic pain. Compared with healthy individuals, the dFC features most highly related to trait neuropathic pain were also more abnormal in patients with greater pain. Our findings indicate that dFC reflects patients' overall pain condition (i.e., trait pain), not just their current state, and is impacted by complexities in pain features beyond intensity.

  5. Time-scale invariance as an emergent property in a perceptron with realistic, noisy neurons

    PubMed Central

    Buhusi, Catalin V.; Oprisan, Sorinel A.

    2013-01-01

    In most species, interval timing is time-scale invariant: errors in time estimation scale up linearly with the estimated duration. In mammals, time-scale invariance is ubiquitous over behavioral, lesion, and pharmacological manipulations. For example, dopaminergic drugs induce an immediate, whereas cholinergic drugs induce a gradual, scalar change in timing. Behavioral theories posit that time-scale invariance derives from particular computations, rules, or coding schemes. In contrast, we discuss a simple neural circuit, the perceptron, whose output neurons fire in a clockwise fashion (interval timing) based on the pattern of coincidental activation of its input neurons. We show numerically that time-scale invariance emerges spontaneously in a perceptron with realistic neurons, in the presence of noise. Under the assumption that dopaminergic drugs modulate the firing of input neurons, and that cholinergic drugs modulate the memory representation of the criterion time, we show that a perceptron with realistic neurons reproduces the pharmacological clock and memory patterns, and their time-scale invariance, in the presence of noise. These results suggest that rather than being a signature of higher-order cognitive processes or specific computations related to timing, time-scale invariance may spontaneously emerge in a massively-connected brain from the intrinsic noise of neurons and circuits, thus providing the simplest explanation for the ubiquity of scale invariance of interval timing. PMID:23518297

  6. Photon-in photon-out hard X-ray spectroscopy at the Linac Coherent Light Source

    DOE PAGES

    Alonso-Mori, Roberto; Sokaras, Dimosthenis; Zhu, Diling; ...

    2015-04-15

    X-ray free-electron lasers (FELs) have opened unprecedented possibilities to study the structure and dynamics of matter at an atomic level and ultra-fast timescale. Many of the techniques routinely used at storage ring facilities are being adapted for experiments conducted at FELs. In order to take full advantage of these new sources several challenges have to be overcome. They are related to the very different source characteristics and its resulting impact on sample delivery, X-ray optics, X-ray detection and data acquisition. Here it is described how photon-in photon-out hard X-ray spectroscopy techniques can be applied to study the electronic structure andmore » its dynamics of transition metal systems with ultra-bright and ultra-short FEL X-ray pulses. In particular, some of the experimental details that are different compared with synchrotron-based setups are discussed and illustrated by recent measurements performed at the Linac Coherent Light Source.« less

  7. Quantum Spin Dynamics with Pairwise-Tunable, Long-Range Interactions

    DTIC Science & Technology

    2016-08-05

    rection of the arrows. Dashed (dotted) lines mark the NNN hopping terms (coefficients ±t2). NNNN long -range hopping along curved lines are included to...Quantum spin dynamics with pairwise-tunable, long -range interactions C.-L. Hunga,b,1,2, Alejandro González-Tudelac,1,2, J. Ignacio Ciracc, and H. J...atoms) that interact by way of a variety of processes, such as atomic collisions. Such pro- cesses typically lead to short -range, nearest-neighbor

  8. Characterization of Polyimide Foams for Ultra-Lightweight Space Structures

    NASA Technical Reports Server (NTRS)

    Meador, Michael (Technical Monitor); Hillman, Keithan; Veazie, David R.

    2003-01-01

    Ultra-lightweight materials have played a significant role in nearly every area of human activity ranging from magnetic tapes and artificial organs to atmospheric balloons and space inflatables. The application range of ultra-lightweight materials in past decades has expanded dramatically due to their unsurpassed efficiency in terms of low weight and high compliance properties. A new generation of ultra-lightweight materials involving advanced polymeric materials, such as TEEK (TM) polyimide foams, is beginning to emerge to produce novel performance from ultra-lightweight systems for space applications. As a result, they require that special conditions be fulfilled to ensure adequate structural performance, shape retention, and thermal stability. It is therefore important and essential to develop methodologies for predicting the complex properties of ultra-lightweight foams. To support NASA programs such as the Reusable Launch Vehicle (RLV), Clark Atlanta University, along with SORDAL, Inc., has initiated projects for commercial process development of polyimide foams for the proposed cryogenic tank integrated structure (see figure 1). Fabrication and characterization of high temperature, advanced aerospace-grade polyimide foams and filled foam sandwich composites for specified lifetimes in NASA space applications, as well as quantifying the lifetime of components, are immensely attractive goals. In order to improve the development, durability, safety, and life cycle performance of ultra-lightweight polymeric foams, test methods for the properties are constant concerns in terms of timeliness, reliability, and cost. A major challenge is to identify the mechanisms of failures (i.e., core failure, interfacial debonding, and crack development) that are reflected in the measured properties. The long-term goal of the this research is to develop the tools and capabilities necessary to successfully engineer ultra-lightweight polymeric foams. The desire is to reduce density

  9. A model for AGN variability on multiple time-scales

    NASA Astrophysics Data System (ADS)

    Sartori, Lia F.; Schawinski, Kevin; Trakhtenbrot, Benny; Caplar, Neven; Treister, Ezequiel; Koss, Michael J.; Urry, C. Megan; Zhang, C. E.

    2018-05-01

    We present a framework to link and describe active galactic nuclei (AGN) variability on a wide range of time-scales, from days to billions of years. In particular, we concentrate on the AGN variability features related to changes in black hole fuelling and accretion rate. In our framework, the variability features observed in different AGN at different time-scales may be explained as realisations of the same underlying statistical properties. In this context, we propose a model to simulate the evolution of AGN light curves with time based on the probability density function (PDF) and power spectral density (PSD) of the Eddington ratio (L/LEdd) distribution. Motivated by general galaxy population properties, we propose that the PDF may be inspired by the L/LEdd distribution function (ERDF), and that a single (or limited number of) ERDF+PSD set may explain all observed variability features. After outlining the framework and the model, we compile a set of variability measurements in terms of structure function (SF) and magnitude difference. We then combine the variability measurements on a SF plot ranging from days to Gyr. The proposed framework enables constraints on the underlying PSD and the ability to link AGN variability on different time-scales, therefore providing new insights into AGN variability and black hole growth phenomena.

  10. Impedance self-matching ultra-narrow linewidth fiber resonator by use of a tunable π-phase-shifted FBG.

    PubMed

    Jing, Mingyong; Yu, Bo; Hu, Jianyong; Hou, Huifang; Zhang, Guofeng; Xiao, Liantuan; Jia, Suotang

    2017-05-15

    In this paper, we present a novel ultra-narrow linewidth fiber resonator formed by a tunable polarization maintaining (PM) π-phase-shifted fiber Bragg grating and a PM uniform fiber Bragg grating with a certain length of PM single mode fiber patch cable between them. Theoretical prediction shows that this resonator has ultra-narrow linewidth resonant peaks and is easy to realize impedance matching. We experimentally obtain 3 MHz narrow linewidth impedance matched resonant peak in a 7.3 m ultra-long passive fiber cavity. The impedance self-matching characteristic of this resonator also makes itself particularly suitable for use in ultra-sensitive sensors, ultra-narrow band rejection optical filters and fiber lasers applications.

  11. Temporal reliability of ultra-high field resting-state MRI for single-subject sensorimotor and language mapping.

    PubMed

    Branco, Paulo; Seixas, Daniela; Castro, São Luís

    2018-03-01

    Resting-state fMRI is a well-suited technique to map functional networks in the brain because unlike task-based approaches it requires little collaboration from subjects. This is especially relevant in clinical settings where a number of subjects cannot comply with task demands. Previous studies using conventional scanner fields have shown that resting-state fMRI is able to map functional networks in single subjects, albeit with moderate temporal reliability. Ultra-high resolution (7T) imaging provides higher signal-to-noise ratio and better spatial resolution and is thus well suited to assess the temporal reliability of mapping results, and to determine if resting-state fMRI can be applied in clinical decision making including preoperative planning. We used resting-state fMRI at ultra-high resolution to examine whether the sensorimotor and language networks are reliable over time - same session and one week after. Resting-state networks were identified for all subjects and sessions with good accuracy. Both networks were well delimited within classical regions of interest. Mapping was temporally reliable at short and medium time-scales as demonstrated by high values of overlap in the same session and one week after for both networks. Results were stable independently of data quality metrics and physiological variables. Taken together, these findings provide strong support for the suitability of ultra-high field resting-state fMRI mapping at the single-subject level. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  12. Long range ultra-high frequency (UHF) radio frequency identification (RFID) antenna design

    NASA Astrophysics Data System (ADS)

    Reynolds, Nathan D.

    There is an ever-increasing demand for radio frequency identification (RFID) tags that are passive, long range, and mountable on multiple surfaces. Currently, RFID technology is utilized in numerous applications such as supply chain management, access control, and public transportation. With the combination of sensory systems in recent years, the applications of RFID technology have been extended beyond tracking and identifying. This extension includes applications such as environmental monitoring and healthcare applications. The available sensory systems usually operate in the medium or high frequency bands and have a low read range. However, the range limitations of these systems are being overcome by the development of RFID sensors focused on utilizing tags in the ultra-high frequency (UHF) band. Generally, RFID tags have to be mounted to the object that is being identified. Often the objects requiring identification are metallic. The inherent properties of metallic objects have substantial effects on nearby electromagnetic radiation; therefore, the operation of the tag antenna is affected when mounted on a metallic surface. This outlines one of the most challenging problems for RFID systems today: the optimization of tag antenna performance in a complex environment. In this research, a novel UHF RFID tag antenna, which has a low profile, long range, and is mountable on metallic surfaces, is designed analytically and simulated using a 3-D electromagnetic simulator, ANSYS HFSS. A microstrip patch antenna is selected as the antenna structure, as patch antennas are low profile and suitable for mounting on metallic surfaces. Matching and theoretical models of the microstrip patch antenna are investigated. Once matching and theory of a microstrip patch antenna is thoroughly understood, a unique design technique using electromagnetic band gap (EBG) structures is explored. This research shows that the utilization of an EBG structure in the patch antenna design yields

  13. Conformational Dynamics of Insulin

    PubMed Central

    Hua, Qing-Xin; Jia, Wenhua; Weiss, Michael A.

    2011-01-01

    We have exploited a prandial insulin analog to elucidate the underlying structure and dynamics of insulin as a monomer in solution. A model was provided by insulin lispro (the active component of Humalog®; Eli Lilly and Co.). Whereas NMR-based modeling recapitulated structural relationships of insulin crystals (T-state protomers), dynamic anomalies were revealed by amide-proton exchange kinetics in D2O. Surprisingly, the majority of hydrogen bonds observed in crystal structures are only transiently maintained in solution, including key T-state-specific inter-chain contacts. Long-lived hydrogen bonds (as defined by global exchange kinetics) exist only at a subset of four α-helical sites (two per chain) flanking an internal disulfide bridge (cystine A20–B19); these sites map within the proposed folding nucleus of proinsulin. The anomalous flexibility of insulin otherwise spans its active surface and may facilitate receptor binding. Because conformational fluctuations promote the degradation of pharmaceutical formulations, we envisage that “dynamic re-engineering” of insulin may enable design of ultra-stable formulations for humanitarian use in the developing world. PMID:22649374

  14. Ultra-long Pt nanolawns supported on TiO2-coated carbon fibers as 3D hybrid catalyst for methanol oxidation

    PubMed Central

    2012-01-01

    In this study, TiO2 thin film photocatalyst on carbon fibers was used to synthesize ultra-long single crystalline Pt nanowires via a simple photoreduction route (thermally activated photoreduction). It also acted as a co-catalytic material with Pt. Taking advantage of the high-aspect ratio of the Pt nanostructure as well as the excellent catalytic activity of TiO2, this hybrid structure has the great potential as the active anode in direct methanol fuel cells. The electrochemical results indicate that TiO2 is capable of transforming CO-like poisoning species on the Pt surface during methanol oxidation and contributes to a high CO tolerance of this Pt nanowire/TiO2 hybrid structure. PMID:22546416

  15. Ultra-long Pt nanolawns supported on TiO2-coated carbon fibers as 3D hybrid catalyst for methanol oxidation

    NASA Astrophysics Data System (ADS)

    Shen, Yu-Lin; Chen, Shih-Yun; Song, Jenn-Ming; Chen, In-Gann

    2012-06-01

    In this study, TiO2 thin film photocatalyst on carbon fibers was used to synthesize ultra-long single crystalline Pt nanowires via a simple photoreduction route (thermally activated photoreduction). It also acted as a co-catalytic material with Pt. Taking advantage of the high-aspect ratio of the Pt nanostructure as well as the excellent catalytic activity of TiO2, this hybrid structure has the great potential as the active anode in direct methanol fuel cells. The electrochemical results indicate that TiO2 is capable of transforming CO-like poisoning species on the Pt surface during methanol oxidation and contributes to a high CO tolerance of this Pt nanowire/TiO2 hybrid structure.

  16. The importance of grain size to mantle dynamics and seismological observations

    NASA Astrophysics Data System (ADS)

    Gassmoeller, R.; Dannberg, J.; Eilon, Z.; Faul, U.; Moulik, P.; Myhill, R.

    2017-12-01

    Grain size plays a key role in controlling the mechanical properties of the Earth's mantle, affecting both long-timescale flow patterns and anelasticity on the timescales of seismic wave propagation. However, dynamic models of Earth's convecting mantle usually implement flow laws with constant grain size, stress-independent viscosity, and a limited treatment of changes in mineral assemblage. We study grain size evolution, its interplay with stress and strain rate in the convecting mantle, and its influence on seismic velocities and attenuation. Our geodynamic models include the simultaneous and competing effects of dynamic recrystallization resulting from dislocation creep, grain growth in multiphase assemblages, and recrystallization at phase transitions. They show that grain size evolution drastically affects the dynamics of mantle convection and the rheology of the mantle, leading to lateral viscosity variations of six orders of magnitude due to grain size alone, and controlling the shape of upwellings and downwellings. Using laboratory-derived scaling relationships, we convert model output to seismologically-observable parameters (velocity, attenuation) facilitating comparison to Earth structure. Reproducing the fundamental features of the Earth's attenuation profile requires reduced activation volume and relaxed shear moduli in the lower mantle compared to the upper mantle, in agreement with geodynamic constraints. Faster lower mantle grain growth yields best fit to seismic observations, consistent with our re-examination of high pressure grain growth parameters. We also show that ignoring grain size in interpretations of seismic anomalies may underestimate the Earth's true temperature variations.

  17. Improve projections of changes in southern African summer rainfall through comprehensive multi-timescale empirical statistical downscaling

    NASA Astrophysics Data System (ADS)

    Dieppois, B.; Pohl, B.; Eden, J.; Crétat, J.; Rouault, M.; Keenlyside, N.; New, M. G.

    2017-12-01

    The water management community has hitherto neglected or underestimated many of the uncertainties in climate impact scenarios, in particular, uncertainties associated with decadal climate variability. Uncertainty in the state-of-the-art global climate models (GCMs) is time-scale-dependant, e.g. stronger at decadal than at interannual timescales, in response to the different parameterizations and to internal climate variability. In addition, non-stationarity in statistical downscaling is widely recognized as a key problem, in which time-scale dependency of predictors plays an important role. As with global climate modelling, therefore, the selection of downscaling methods must proceed with caution to avoid unintended consequences of over-correcting the noise in GCMs (e.g. interpreting internal climate variability as a model bias). GCM outputs from the Coupled Model Intercomparison Project 5 (CMIP5) have therefore first been selected based on their ability to reproduce southern African summer rainfall variability and their teleconnections with Pacific sea-surface temperature across the dominant timescales. In observations, southern African summer rainfall has recently been shown to exhibit significant periodicities at the interannual timescale (2-8 years), quasi-decadal (8-13 years) and inter-decadal (15-28 years) timescales, which can be interpret as the signature of ENSO, the IPO, and the PDO over the region. Most of CMIP5 GCMs underestimate southern African summer rainfall variability and their teleconnections with Pacific SSTs at these three timescales. In addition, according to a more in-depth analysis of historical and pi-control runs, this bias is might result from internal climate variability in some of the CMIP5 GCMs, suggesting potential for bias-corrected prediction based empirical statistical downscaling. A multi-timescale regression based downscaling procedure, which determines the predictors across the different timescales, has thus been used to

  18. RuO2 Thermometer for Ultra-Low Temperatures

    NASA Technical Reports Server (NTRS)

    Hait, Thomas; Shirron, Peter J.; DiPirro, Michael

    2009-01-01

    A small, high-resolution, low-power thermometer has been developed for use in ultra-low temperatures that uses multiple RuO2 chip resistors. The use of commercially available thick-film RuO2 chip resistors for measuring cryogenic temperatures is well known due to their low cost, long-term stability, and large resistance change.

  19. Long-term dynamics and characteristics of snags created for wildlife habitat

    USGS Publications Warehouse

    Barry, Amy M.; Hagar, Joan; Rivers, James W.

    2017-01-01

    Snags provide essential habitat for numerous organisms and are therefore critical to the long-term maintenance of forest biodiversity. Resource managers often use snag creation to mitigate the purposeful removal of snags at the time of harvest, but information regarding how created snags change over long timescales (>20 y) is absent from the literature. In this study, we evaluated the extent to which characteristics of large (>30 cm diameter at breast height [DBH]) Douglas-fir (Pseudotsuga menziesii) snags created by topping had changed after 25–27 y. We also tested whether different harvest treatments and snag configurations influenced present-day snag characteristics. Of 690 snags created in 1989–1991, 91% remained standing during contemporary surveys and 65% remained unbroken along the bole. Although most snags were standing, we detected increased bark loss and breaking along the bole relative to prior surveys conducted on the same pool of snags. Although snag characteristics were not strongly influenced by snag configuration, we found that snags in one harvest treatment (group selection) experienced less bark loss and had lower evidence of use by cavity-nesting birds (as measured by total cavity cover) relative to snags created with clearcut and two-story harvest treatments. Our results indicate that Douglas-fir snags created by topping can remain standing for long time-periods (≥25 y) in managed forests, and that the influence of harvest treatment on decay patterns and subsequent use by wildlife is an important consideration when intentionally creating snags for wildlife habitat.

  20. Naturally rare versus newly rare: demographic inferences on two timescales inform conservation of Galápagos giant tortoises

    PubMed Central

    Garrick, Ryan C; Kajdacsi, Brittney; Russello, Michael A; Benavides, Edgar; Hyseni, Chaz; Gibbs, James P; Tapia, Washington; Caccone, Adalgisa

    2015-01-01

    Long-term population history can influence the genetic effects of recent bottlenecks. Therefore, for threatened or endangered species, an understanding of the past is relevant when formulating conservation strategies. Levels of variation at neutral markers have been useful for estimating local effective population sizes (Ne) and inferring whether population sizes increased or decreased over time. Furthermore, analyses of genotypic, allelic frequency, and phylogenetic information can potentially be used to separate historical from recent demographic changes. For 15 populations of Galápagos giant tortoises (Chelonoidis sp.), we used 12 microsatellite loci and DNA sequences from the mitochondrial control region and a nuclear intron, to reconstruct demographic history on shallow (past ∽100 generations, ∽2500 years) and deep (pre-Holocene, >10 thousand years ago) timescales. At the deep timescale, three populations showed strong signals of growth, but with different magnitudes and timing, indicating different underlying causes. Furthermore, estimated historical Ne of populations across the archipelago showed no correlation with island age or size, underscoring the complexity of predicting demographic history a priori. At the shallow timescale, all populations carried some signature of a genetic bottleneck, and for 12 populations, point estimates of contemporary Ne were very small (i.e., < 50). On the basis of the comparison of these genetic estimates with published census size data, Ne generally represented ∽0.16 of the census size. However, the variance in this ratio across populations was considerable. Overall, our data suggest that idiosyncratic and geographically localized forces shaped the demographic history of tortoise populations. Furthermore, from a conservation perspective, the separation of demographic events occurring on shallow versus deep timescales permits the identification of naturally rare versus newly rare populations; this distinction should

  1. High-frequency chaotic dynamics enabled by optical phase-conjugation

    PubMed Central

    Mercier, Émeric; Wolfersberger, Delphine; Sciamanna, Marc

    2016-01-01

    Wideband chaos is of interest for applications such as random number generation or encrypted communications, which typically use optical feedback in a semiconductor laser. Here, we show that replacing conventional optical feedback with phase-conjugate feedback improves the chaos bandwidth. In the range of achievable phase-conjugate mirror reflectivities, the bandwidth increase reaches 27% when compared with feedback from a conventional mirror. Experimental measurements of the time-resolved frequency dynamics on nanosecond time-scales show that the bandwidth enhancement is related to the onset of self-pulsing solutions at harmonics of the external-cavity frequency. In the observed regime, the system follows a chaotic itinerancy among these destabilized high-frequency external-cavity modes. The recorded features are unique to phase-conjugate feedback and distinguish it from the long-standing problem of time-delayed feedback dynamics. PMID:26739806

  2. Visualizing an ultra-weak protein-protein interaction in phosphorylation signaling.

    PubMed

    Xing, Qiong; Huang, Peng; Yang, Ju; Sun, Jian-Qiang; Gong, Zhou; Dong, Xu; Guo, Da-Chuan; Chen, Shao-Min; Yang, Yu-Hong; Wang, Yan; Yang, Ming-Hui; Yi, Ming; Ding, Yi-Ming; Liu, Mai-Li; Zhang, Wei-Ping; Tang, Chun

    2014-10-20

    Proteins interact with each other to fulfill their functions. The importance of weak protein-protein interactions has been increasingly recognized. However, owing to technical difficulties, ultra-weak interactions remain to be characterized. Phosphorylation can take place via a K(D)≈25 mM interaction between two bacterial enzymes. Using paramagnetic NMR spectroscopy and with the introduction of a novel Gd(III)-based probe, we determined the structure of the resulting complex to atomic resolution. The structure accounts for the mechanism of phosphoryl transfer between the two enzymes and demonstrates the physical basis for their ultra-weak interaction. Further, molecular dynamics (MD) simulations suggest that the complex has a lifetime in the micro- to millisecond regimen. Hence such interaction is termed a fleeting interaction. From mathematical modeling, we propose that an ultra-weak fleeting interaction enables rapid flux of phosphoryl signal, providing a high effective protein concentration. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Wavelet-based variability of Yellow River discharge at 500-, 100-, and 50-year timescales

    NASA Astrophysics Data System (ADS)

    Su, Lu; Miao, Chiyuan; Duan, Qingyun

    2017-04-01

    Water scarcity in the Yellow River, China, has become increasingly severe over the past half century. In this paper, wavelet transform analysis was used to detect the variability of observed and reconstructed streamflow in the Yellow River at 500-, 100-, and 50-year timescales. The periodicity of the streamflow series and the co-varying relationships between streamflow and atmospheric circulation indices / sunspot number were assessed via the continuous wavelet transform (CWT) and the wavelet coherence transform (WTC). The CWT results showed intermittent oscillations in streamflow with increasing periodicities of 1-6 years at all timescales. Significant multidecadal and century-scale periodicities were identified in the 500-year streamflow series. The WTC results showed intermittent interannual covariance of streamflow with atmospheric circulation indices and sunspots. At the 50-year timescale, there were significant decadal oscillations between streamflow and the Arctic Oscillation (AO) and the Pacific Decadal Oscillation (PDO), and bidecadal oscillations with the PDO. At the 100-year timescale, there were significant decadal oscillations between streamflow and Niño 3.4, the AO, and sunspots. At the 500-year timescale, streamflow in the middle reaches of the Yellow River showed prominent covariance with the AO with an approximately 32-year periodicity, and with sunspots with an approximately 80-year periodicity. Atmospheric circulation indices modulate streamflow by affecting temperature and precipitation. Sunspots impact streamflow variability by influencing atmospheric circulation, resulting in abundant precipitation. In general, for both the CWT and the WTC results, the periodicities were spatially continuous, with a few gradual changes from upstream to downstream resulting from the varied topography and runoff. At the temporal scale, the periodicities were generally continuous over short timescales and discontinuous over longer timescales.

  4. Wavelet-based Variability of Yellow River Discharge at 500-, 100-, and 50-Year Timescales

    NASA Astrophysics Data System (ADS)

    Su, L.

    2017-12-01

    Water scarcity in the Yellow River, China, has become increasingly severe over the past half century. In this paper, wavelet transform analysis was used to detect the variability of natural, observed, and reconstructed streamflow in the Yellow River at 500-, 100-, and 50-year timescales. The periodicity of the streamflow series and the co-varying relationships between streamflow and atmospheric circulation indices/sunspot number were assessed by means of continuous wavelet transform (CWT) and wavelet transform coherence (WTC) analyses. The CWT results showed intermittent oscillations in streamflow with increasing periodicities of 1-6 years at all timescales. Significant multidecadal and century-scale periodicities were identified in the 500-year streamflow series. The WTC results showed intermittent interannual covariance of streamflow with atmospheric circulation indices and sunspots. At the 50-year timescale, there were significant decadal oscillations between streamflow and the Arctic Oscillation (AO) and the Pacific Decadal Oscillation (PDO), and bidecadal oscillations with the PDO. At the 100-year timescale, there were significant decadal oscillations between streamflow and Niño 3.4, the AO, and sunspots. At the 500-year timescale, streamflow in the middle reaches of the Yellow River showed prominent covariance with the AO with an approximately 32-year periodicity, and with sunspots with an approximately 80-year periodicity. Atmospheric circulation indices modulate streamflow by affecting temperature and precipitation. Sunspots impact streamflow variability by influencing atmospheric circulation, resulting in abundant precipitation. In general, for both the CWT and the WTC results, the periodicities were spatially continuous, with a few gradual changes from upstream to downstream resulting from the varied topography and runoff. At the temporal scale, the periodicities were generally continuous over short timescales and discontinuous over longer timescales.

  5. Similar star formation rate and metallicity variability time-scales drive the fundamental metallicity relation

    NASA Astrophysics Data System (ADS)

    Torrey, Paul; Vogelsberger, Mark; Hernquist, Lars; McKinnon, Ryan; Marinacci, Federico; Simcoe, Robert A.; Springel, Volker; Pillepich, Annalisa; Naiman, Jill; Pakmor, Rüdiger; Weinberger, Rainer; Nelson, Dylan; Genel, Shy

    2018-06-01

    The fundamental metallicity relation (FMR) is a postulated correlation between galaxy stellar mass, star formation rate (SFR), and gas-phase metallicity. At its core, this relation posits that offsets from the mass-metallicity relation (MZR) at a fixed stellar mass are correlated with galactic SFR. In this Letter, we use hydrodynamical simulations to quantify the time-scales over which populations of galaxies oscillate about the average SFR and metallicity values at fixed stellar mass. We find that Illustris and IllustrisTNG predict that galaxy offsets from the star formation main sequence and MZR oscillate over similar time-scales, are often anticorrelated in their evolution, evolve with the halo dynamical time, and produce a pronounced FMR. Our models indicate that galaxies oscillate about equilibrium SFR and metallicity values - set by the galaxy's stellar mass - and that SFR and metallicity offsets evolve in an anticorrelated fashion. This anticorrelated variability of the metallicity and SFR offsets drives the existence of the FMR in our models. In contrast to Illustris and IllustrisTNG, we speculate that the SFR and metallicity evolution tracks may become decoupled in galaxy formation models dominated by feedback-driven globally bursty SFR histories, which could weaken the FMR residual correlation strength. This opens the possibility of discriminating between bursty and non-bursty feedback models based on the strength and persistence of the FMR - especially at high redshift.

  6. Performance Improvement of Receivers Based on Ultra-Tight Integration in GNSS-Challenged Environments

    PubMed Central

    Qin, Feng; Zhan, Xingqun; Du, Gang

    2013-01-01

    Ultra-tight integration was first proposed by Abbott in 2003 with the purpose of integrating a global navigation satellite system (GNSS) and an inertial navigation system (INS). This technology can improve the tracking performances of a receiver by reconfiguring the tracking loops in GNSS-challenged environments. In this paper, the models of all error sources known to date in the phase lock loops (PLLs) of a standard receiver and an ultra-tightly integrated GNSS/INS receiver are built, respectively. Based on these models, the tracking performances of the two receivers are compared to verify the improvement due to the ultra-tight integration. Meanwhile, the PLL error distributions of the two receivers are also depicted to analyze the error changes of the tracking loops. These results show that the tracking error is significantly reduced in the ultra-tightly integrated GNSS/INS receiver since the receiver's dynamics are estimated and compensated by an INS. Moreover, the mathematical relationship between the tracking performances of the ultra-tightly integrated GNSS/INS receiver and the quality of the selected inertial measurement unit (IMU) is derived from the error models and proved by the error comparisons of four ultra-tightly integrated GNSS/INS receivers aided by different grade IMUs.

  7. Development of a Family of Ultra-High Performance Concrete Pi-Girders

    DOT National Transportation Integrated Search

    2014-01-01

    Ultra-high performance concrete (UHPC) is an advanced cementitious composite material, which tends to exhibit superior properties such as exceptional durability, increased strength, and long-term stability. (See references 1-4.) The use of existing s...

  8. QUASI-PERIODICITIES AT YEAR-LIKE TIMESCALES IN BLAZARS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sandrinelli, A.; Treves, A.; Covino, S.

    2016-03-15

    We searched for quasi-periodicities on year-like timescales in the light curves of six blazars in the optical—near-infrared bands and we made a comparison with the high energy emission. We obtained optical/NIR light curves from Rapid Eye Mounting photometry plus archival Small and Moderate Aperture Research Telescope System data and we accessed the Fermi light curves for the γ-ray data. The periodograms often show strong peaks in the optical and γ-ray bands, which in some cases may be inter-related. The significance of the revealed peaks is then discussed, taking into account that the noise is frequency dependent. Quasi-periodicities on a year-likemore » timescale appear to occur often in blazars. No straightforward model describing these possible periodicities is yet available, but some plausible interpretations for the physical mechanisms causing periodic variabilities of these sources are examined.« less

  9. A mechanical characterisation on multiple timescales of electroconductive magnetorheological elastomers

    NASA Astrophysics Data System (ADS)

    Schümann, M.; Morich, J.; Kaufhold, T.; Böhm, V.; Zimmermann, K.; Odenbach, S.

    2018-05-01

    Magnetorheological elastomers are a type of smart hybrid material which combines elastic properties of a soft elastomer matrix with magnetic properties of magnetic micro particles. This leads to a material with magnetically controllable mechanical properties of which the magnetorheological effect is the best known. The addition of electroconductive particles to the polymer mix adds electrical properties to the material behaviour. The resulting electrical resistance of the sample can be manipulated by external magnetic fields and mechanical loads. This results in a distinct interplay of mechanical, electrical and magnetic effects with a highly complex time behaviour. In this paper a mechanical characterisation on multiple time scales was conducted to get an insight on the short and long-term electrical and mechanical behaviour of this novel material. The results show a complex resistivity behaviour on several timescales, sensitive to magnetic fields and strain velocity. The observed material exhibits fatigue and relaxation behaviour, whereas the magnetorheological effect appears not to interfere with the piezoresistive properties.

  10. Application of ultra-small-angle X-ray scattering / X-ray photon correlation spectroscopy to relate equilibrium or non-equilibrium dynamics to microstructure

    NASA Astrophysics Data System (ADS)

    Allen, Andrew; Zhang, Fan; Levine, Lyle; Ilavsky, Jan

    2013-03-01

    Ultra-small-angle X-ray scattering (USAXS) can probe microstructures over the nanometer-to-micrometer scale range. Through use of a small instrument entrance slit, X-ray photon correlation spectroscopy (XPCS) exploits the partial coherence of an X-ray synchrotron undulator beam to provide unprecedented sensitivity to the dynamics of microstructural change. In USAXS/XPCS studies, the dynamics of local structures in a scale range of 100 nm to 1000 nm can be related to an overall hierarchical microstructure extending from 1 nm to more than 1000 nm. Using a point-detection scintillator mode, the equilibrium dynamics at ambient temperature of small particles (which move more slowly than nanoparticles) in aqueous suspension have been quantified directly for the first time. Using a USAXS-XPCS scanning mode for non-equilibrium dynamics incipient processes within dental composites have been elucidated, prior to effects becoming detectable using any other technique. Use of the Advanced Photon Source, an Office of Science User Facility operated for the United States Department of Energy (U.S. DOE) Office of Science by Argonne National Laboratory, was supported by the U.S. DOE under Contract No. DE-AC02-06CH11357.

  11. A New Approach on the Long Term Dynamics of NEO's Under Yarkovsky Effect.

    NASA Astrophysics Data System (ADS)

    Peláez, Jesús; Urrutxua, Hodei; Bombardelli, Claudio; Perez-Grande, Isabel

    2011-12-01

    A classical approach to the many-body problem is that of using special perturbation methods. Nowadays and due to the availability of high-speed computers is an essential tool in Space Dynamics which exhibits a great advantage: it is applicable to any orbit involving any number of bodies and all sorts of astrodynamical problems, especially when these problems fall into regions in which general perturbation theories are absent. One such case is, for example, that Near Earth Objects (NEO's) dynamics. In this field, the Group of Tether Dynamics of UPM (GDT) has developed a new regularisation scheme - called DROMO - which is characterised by only 8 ODE. This new regularisation scheme allows a new approach to the dynamics of NEO's in the long term, specially appropriated to consider the influence of the anisotropic thermal emission (Yarkovsky and YORP effects) on the dynamics. A new project, called NEODROMO, has been started in GDT that aims to provide a reliable tool for the long term dynamics of NEO's.

  12. The value of improved wind power forecasting: Grid flexibility quantification, ramp capability analysis, and impacts of electricity market operation timescales

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Qin; Wu, Hongyu; Florita, Anthony R.

    The value of improving wind power forecasting accuracy at different electricity market operation timescales was analyzed by simulating the IEEE 118-bus test system as modified to emulate the generation mixes of the Midcontinent, California, and New England independent system operator balancing authority areas. The wind power forecasting improvement methodology and error analysis for the data set were elaborated. Production cost simulation was conducted on the three emulated systems with a total of 480 scenarios, considering the impacts of different generation technologies, wind penetration levels, and wind power forecasting improvement timescales. The static operational flexibility of the three systems was comparedmore » through the diversity of generation mix, the percentage of must-run baseload generators, as well as the available ramp rate and the minimum generation levels. The dynamic operational flexibility was evaluated by the real-time upward and downward ramp capacity. Simulation results show that the generation resource mix plays a crucial role in evaluating the value of improved wind power forecasting at different timescales. In addition, the changes in annual operational electricity generation costs were mostly influenced by the dominant resource in the system. Lastly, the impacts of pumped-storage resources, generation ramp rates, and system minimum generation level requirements on the value of improved wind power forecasting were also analyzed.« less

  13. The value of improved wind power forecasting: Grid flexibility quantification, ramp capability analysis, and impacts of electricity market operation timescales

    DOE PAGES

    Wang, Qin; Wu, Hongyu; Florita, Anthony R.; ...

    2016-11-11

    The value of improving wind power forecasting accuracy at different electricity market operation timescales was analyzed by simulating the IEEE 118-bus test system as modified to emulate the generation mixes of the Midcontinent, California, and New England independent system operator balancing authority areas. The wind power forecasting improvement methodology and error analysis for the data set were elaborated. Production cost simulation was conducted on the three emulated systems with a total of 480 scenarios, considering the impacts of different generation technologies, wind penetration levels, and wind power forecasting improvement timescales. The static operational flexibility of the three systems was comparedmore » through the diversity of generation mix, the percentage of must-run baseload generators, as well as the available ramp rate and the minimum generation levels. The dynamic operational flexibility was evaluated by the real-time upward and downward ramp capacity. Simulation results show that the generation resource mix plays a crucial role in evaluating the value of improved wind power forecasting at different timescales. In addition, the changes in annual operational electricity generation costs were mostly influenced by the dominant resource in the system. Lastly, the impacts of pumped-storage resources, generation ramp rates, and system minimum generation level requirements on the value of improved wind power forecasting were also analyzed.« less

  14. Probing the role of long-range interactions in the dynamics of a long-range Kitaev chain

    NASA Astrophysics Data System (ADS)

    Dutta, Anirban; Dutta, Amit

    2017-09-01

    We study the role of long-range interactions (more precisely, the long-range superconducting gap term) on the nonequilibrium dynamics considering a long-range p -wave superconducting chain in which the superconducting term decays with distance between two sites in a power-law fashion characterized by an exponent α . We show that the Kibble-Zurek scaling exponent, dictating the power-law decay of the defect density in the final state reached following a slow (in comparison to the time scale associated with the minimum gap in the spectrum of the Hamiltonian) quenching of the chemical potential μ across a quantum critical point, depends nontrivially on the exponent α as long as α <2 ; on the other hand, for α >2 , we find that the exponent saturates to the corresponding well-known value of 1 /2 expected for the short-range model. Furthermore, studying the dynamical quantum phase transitions manifested in the nonanalyticities in the rate function of the return possibility I (t ) in subsequent temporal evolution following a sudden change in μ , we show the existence of a new region; in this region, we find three instants of cusp singularities in I (t ) associated with a single sector of Fisher zeros. Notably, the width of this region shrinks as α increases and vanishes in the limit α →2 , indicating that this special region is an artifact of the long-range nature of the Hamiltonian.

  15. Singular dynamics and emergence of nonlocality in long-range quantum models

    NASA Astrophysics Data System (ADS)

    Lepori, L.; Trombettoni, A.; Vodola, D.

    2017-03-01

    We discuss how nonlocality originates in long-range quantum systems and how it affects their dynamics at and out of equilibrium. We focus in particular on the Kitaev chains with long-range pairings and on the quantum Ising chain with long-range antiferromagnetic coupling (both having a power-law decay with exponent α). By studying the dynamic correlation functions, we find that for every finite α two different behaviours can be identified, one typical of short-range systems and the other connected with locality violation. The latter behaviour is shown related also with the known power-law decay tails previously observed in the static correlation functions, and originated by modes—having in general energies far from the minima of the spectrum—where particular singularities develop as a consequence of the long-rangedness of the system. We refer to these modes as to ‘singular’ modes, and as to ‘singular dynamics’ to their dynamics. For the Kitaev model they are manifest, at finite α, in derivatives of the quasiparticle energy, the order of the derivatives at which the singularity occurs is increasing with α. The features of the singular modes and their physical consequences are clarified by studying an effective theory for them and by a critical comparison of the results from this theory with the lattice ones. Moreover, a numerical study of the effects of the singular modes on the time evolution after various types of global quenches is performed. We finally present and discuss the presence of singular modes and their consequences in interacting long-range systems by investigating in the long-range Ising quantum chain, both in the deep paramagnetic regime and at criticality, where they also play a central role for the breakdown of conformal invariance.

  16. Simultaneous structural and environmental loading of an ultra-high performance concrete component

    DOT National Transportation Integrated Search

    2010-07-01

    Ultra-high performance concrete (UHPC) is an advanced cementitious composite material which tends to exhibit superior properties such as increased durability, strength, and long-term stability. This experimental investigation focused on the flexural ...

  17. Formation Timescales for High-Mass X-ray Binaries in M33

    NASA Astrophysics Data System (ADS)

    Garofali, Kristen; Williams, Benjamin F.; Hillis, Tristan; Gilbert, Karoline M.; Dolphin, Andrew E.; Eracleous, Michael; Binder, Breanna

    2018-06-01

    We have identified 55 candidate high-mass X-ray binaries (HMXBs) in M33 using available archival HST and Chandra imaging to find blue stars associated with X-ray positions. We use the HST photometric data to model the color-magnitude diagrams in the vicinity of each candidate HMXB to measure a resolved recent star formation history (SFH), and thus a formation timescale, or age for the source. Taken together, the SFHs for all candidate HMXBs in M33 yield an age distribution that suggests preferred formation timescales for HMXBs in M33 of < 5 Myr and ˜ 40 Myr after the initial star formation episode. The population at 40 Myr is seen in other Local Group galaxies, and can be attributed to a peak in formation efficiency of HMXBs with neutron stars as compact objects and B star secondary companions. This timescale is preferred as neutron stars should form in abundance from ˜ 8 M⊙ core-collapse progenitors on these timescales, and B stars are shown observationally to be most actively losing mass around this time. The young population at < 5 Myr has not be observed in other Local Group HMXB population studies, but may be attributed to a population of very massive progenitors forming black holes very early on. We discuss these results in the context of massive binary evolution, and the implications for compact object binaries and gravitational wave sources.

  18. Potential and timescales for oxygen depletion in coastal upwelling systems: A box-model analysis

    NASA Astrophysics Data System (ADS)

    Harrison, C. S.; Hales, B.; Siedlecki, S.; Samelson, R. M.

    2016-05-01

    A simple box model is used to examine oxygen depletion in an idealized ocean-margin upwelling system. Near-bottom oxygen depletion is controlled by a competition between flushing with oxygenated offshore source waters and respiration of particulate organic matter produced near the surface and retained near the bottom. Upwelling-supplied nutrients are consumed in the surface box, and some surface particles sink to the bottom where they respire, consuming oxygen. Steady states characterize the potential for hypoxic near-bottom oxygen depletion; this potential is greatest for faster sinking rates, and largely independent of production timescales except in that faster production allows faster sinking. Timescales for oxygen depletion depend on upwelling and productivity differently, however, as oxygen depletion can only be reached in meaningfully short times when productivity is rapid. Hypoxia thus requires fast production, to capture upwelled nutrients, and fast sinking, to deliver the respiration potential to model bottom waters. Combining timescales allows generalizations about tendencies toward hypoxia. If timescales of sinking are comparable to or smaller than the sum of those for respiration and flushing, the steady state will generally be hypoxic, and results indicate optimal timescales and conditions exist to generate hypoxia. For example, the timescale for approach to hypoxia lengthens with stronger upwelling, since surface particle and nutrient are shunted off-shelf, in turn reducing subsurface respiration and oxygen depletion. This suggests that if upwelling winds intensify with climate change the increased forcing could offer mitigation of coastal hypoxia, even as the oxygen levels in upwelled source waters decline.

  19. Synthetic Spin-Orbit and Light Field Coupling in Ultra-cold Quantum Gases

    NASA Astrophysics Data System (ADS)

    Dong, Lin

    Ultra-cold quantum gases subjected to light-induced synthetic gauge potentials have become an emergent field of theoretical and experimental studies. Because of the novel application of two-photon Raman transitions, ultra-cold neutral atoms behave like charged particles in magnetic field. The Raman coupling naturally gives rise to an effective spin-orbit interaction which couples the atoms center-of-mass motion to its selected pseudo-spin degrees of freedom. Combined with unprecedented controllability of interactions, geometry, disorder strength, spectroscopy, and high resolution measurement of momentum distribution, etc., we are truly in an exciting era of fulfilling and going beyond Richard Feynman's vision. of realizing quantum simulators to better understand the quantum mechanical nature of the universe, manifested immensely in the ultra-cold regimes. In this dissertation, we present a collection of theoretical progresses made by the doctoral candidate and his colleagues and collaborators. From the past few years of work, we mainly address three aspects of the synthetic spin-orbit and light field induced coupling in ultracold quantum gases: a) The ground-state physics of singleparticle system, two-body bound states, and many-body systems, all of which are subjected to spin-orbit coupling originated from synthetic gauge potentials; b) The symmetry breaking, topological phase transition and quench dynamics, which are conveniently offered by the realized experimental setup; c) The proposal and implications of light field induced dynamical spin-orbit coupling for atoms inside optical cavity. Our work represents an important advancement of theoretical understanding to the active research frontier of ultra-cold atom physics with spin-orbit coupling.

  20. Constraining Regolith Production on a Hillslope Over Long Timescales: Interpreting In Situ 10Be Concentrations on an Evolving Landscape

    NASA Astrophysics Data System (ADS)

    Foster, M. A.; Anderson, R. S.; Duehnforth, M.; Kelly, P. J.

    2011-12-01

    numerical hillslope model in which regolith thickness and 10Be concentration are tracked at all hillslope positions. 10Be concentration in rock immediately subjacent to the regolith is updated both by decay and by production at a rate governed by the instantaneous regolith thickness (e.g. Riggins et al., 2011). Vertically averaged 10Be concentration in the regolith is updated by vertically averaged production rate, decay, addition from rock released at the base of the regolith, and advection of regolith. The resulting field of 10Be in bedrock at the regolith interface, from which one deduces long term average regolith production rates, varies both in time and in space. Our model indicates that regolith thickness fluctuates by tens of percent from the average condition over the timescale of glacial-interglacial cycles. The resulting shifts in 10Be concentrations at the base of regolith are of similar magnitude, with greater shifts of 10Be concentrations in regolith. We will employ this model tuned to the Gordon Gulch sites to interpret measured 10Be concentrations.

  1. Ultra-long-period fiber grating cascaded to a knob-taper for simultaneous measurement of strain and temperature

    NASA Astrophysics Data System (ADS)

    Tong, Chengguo; Chen, Xudong; Zhou, Yu; He, Jiang; Yang, Wenlei; Geng, Tao; Sun, Weimin; Yuan, Libo

    2018-06-01

    This study presents a simple Mach-Zehnder interferometer (MZI) to obtain the bimodal characteristics that realize simultaneous measurement of strain and temperature through cascading an ultra-long-period fiber grating and a knob-shaped taper. We obtain the multi-dip feature from the MZI, and the Dips 2 and 5 are selected from 11 interference dips. Experimental results indicated that the wavelength sensitivities of Dips 2 and 5 are - 0.54 nm mɛ-1 and 0.058 nm °C-1, and - 0.53 nm mɛ-1 and 0.055 nm °C-1 to strain and temperature, respectively. The depth sensitivities are - 3.3 dB mɛ- 1, - 0.015 dB °C-1 and -5.8 dB mɛ-1, and 0.06 dB °C-1 for Dips 2 and 5, respectively. It is concluded that the proposed structure is suitable for simultaneous strain and temperature measurements.

  2. Ultra-long-period fiber grating cascaded to a knob-taper for simultaneous measurement of strain and temperature

    NASA Astrophysics Data System (ADS)

    Tong, Chengguo; Chen, Xudong; Zhou, Yu; He, Jiang; Yang, Wenlei; Geng, Tao; Sun, Weimin; Yuan, Libo

    2018-03-01

    This study presents a simple Mach-Zehnder interferometer (MZI) to obtain the bimodal characteristics that realize simultaneous measurement of strain and temperature through cascading an ultra-long-period fiber grating and a knob-shaped taper. We obtain the multi-dip feature from the MZI, and the Dips 2 and 5 are selected from 11 interference dips. Experimental results indicated that the wavelength sensitivities of Dips 2 and 5 are - 0.54 nm mɛ-1 and 0.058 nm °C-1, and - 0.53 nm mɛ-1 and 0.055 nm °C-1 to strain and temperature, respectively. The depth sensitivities are - 3.3 dB mɛ- 1, - 0.015 dB °C-1 and -5.8 dB mɛ-1, and 0.06 dB °C-1 for Dips 2 and 5, respectively. It is concluded that the proposed structure is suitable for simultaneous strain and temperature measurements.

  3. Past Holocene detritism quantification and modeling from lacustrine archives in order to deconvoluate human-climate interactions on natural ecosystem over long time-scale

    NASA Astrophysics Data System (ADS)

    Simonneau, Anaëlle; Chapron, Emmanuel; Di Giovanni, Christian; Galop, Didier; Darboux, Frédéric

    2014-05-01

    Water budget is one of the main challenges to paleoclimate researchers in relation to present-day global warming and its consequences for human societies. Associated soil degradation and erosion are thereby becoming a major concern in many parts of the world and more particularly in the Alps. Moreover, humans are considered as geomorphologic agents since few thousand years and it is now recognized that such an impact on natural ecosystem profoundly modified soils properties as well as aquatic ecosystems dynamics over long-term periods. The quantification of such inference over long time-scale is therefore essential to establish new policies to reduce mechanic soil erosion, which is one of the dominant processes in Europe, and anticipate the potential consequences of future climate change on hydric erosion. The mechanical erosion of continental surfaces results from climatic forcing, but can be amplified by the anthropogenic one. We therefore suggest that quantifying and modelling soil erosion processes within comparable Holocene lacustrine archives, allows to estimate and date which and when past human activities have had an impact on soil fluxes over the last 10000 years. Based on the present-day geomorphology of the surrounding watershed and the evolution of the vegetation cover during the Holocene, we develop an interdisciplinary approach combining quantitative organic petrography (i.e. optical characterization and quantification of soil particles within lake sediments) with high-resolution seismic profiling, age-depth models on lacustrine sediment cores and soil erosional susceptibility modeling, in order to estimate the annual volume of soil eroded over the last 10000 years, and in fine to quantify the volume of human-induced soil erosion during the Holocene period. This method is applied to close but contrasted mountainous lacustrine environments from the western French Alps: lakes Blanc Huez and Paladru, sensitive to same climatic influences but where past

  4. Doubly stochastic Poisson process models for precipitation at fine time-scales

    NASA Astrophysics Data System (ADS)

    Ramesh, Nadarajah I.; Onof, Christian; Xie, Dichao

    2012-09-01

    This paper considers a class of stochastic point process models, based on doubly stochastic Poisson processes, in the modelling of rainfall. We examine the application of this class of models, a neglected alternative to the widely-known Poisson cluster models, in the analysis of fine time-scale rainfall intensity. These models are mainly used to analyse tipping-bucket raingauge data from a single site but an extension to multiple sites is illustrated which reveals the potential of this class of models to study the temporal and spatial variability of precipitation at fine time-scales.

  5. Non-radiative relaxation dynamics of pyrrole following excitation in the range 249.5-200 nm

    NASA Astrophysics Data System (ADS)

    Kirkby, Oliver M.; Parkes, Michael A.; Neville, Simon P.; Worth, Graham A.; Fielding, Helen H.

    2017-09-01

    The non-radiative relaxation dynamics of pyrrole have been investigated using time-resolved photoelectron spectroscopy and quantum dynamics simulations. Following excitation of the A2 (11 πσ∗) state, we observe population flow out of the Franck-Condon region on a ≲ 50 fs timescale. Following excitation of the B2 (21 ππ∗) state, we observe population being transferred to the A2 (11 πσ∗) state on a <50 fs timescale and subsequently out of the Franck-Condon region, also on a <50 fs timescale. Quantum dynamics calculations suggest that population is transferred from the B2 (21 ππ∗) state through the A2 (1 π 3pz) state to the B1 (21 πσ∗) state before being transferred to the A2 (11 πσ∗) state.

  6. Fundamental structures of dynamic social networks.

    PubMed

    Sekara, Vedran; Stopczynski, Arkadiusz; Lehmann, Sune

    2016-09-06

    Social systems are in a constant state of flux, with dynamics spanning from minute-by-minute changes to patterns present on the timescale of years. Accurate models of social dynamics are important for understanding the spreading of influence or diseases, formation of friendships, and the productivity of teams. Although there has been much progress on understanding complex networks over the past decade, little is known about the regularities governing the microdynamics of social networks. Here, we explore the dynamic social network of a densely-connected population of ∼1,000 individuals and their interactions in the network of real-world person-to-person proximity measured via Bluetooth, as well as their telecommunication networks, online social media contacts, geolocation, and demographic data. These high-resolution data allow us to observe social groups directly, rendering community detection unnecessary. Starting from 5-min time slices, we uncover dynamic social structures expressed on multiple timescales. On the hourly timescale, we find that gatherings are fluid, with members coming and going, but organized via a stable core of individuals. Each core represents a social context. Cores exhibit a pattern of recurring meetings across weeks and months, each with varying degrees of regularity. Taken together, these findings provide a powerful simplification of the social network, where cores represent fundamental structures expressed with strong temporal and spatial regularity. Using this framework, we explore the complex interplay between social and geospatial behavior, documenting how the formation of cores is preceded by coordination behavior in the communication networks and demonstrating that social behavior can be predicted with high precision.

  7. Fundamental structures of dynamic social networks

    PubMed Central

    Sekara, Vedran; Stopczynski, Arkadiusz; Lehmann, Sune

    2016-01-01

    Social systems are in a constant state of flux, with dynamics spanning from minute-by-minute changes to patterns present on the timescale of years. Accurate models of social dynamics are important for understanding the spreading of influence or diseases, formation of friendships, and the productivity of teams. Although there has been much progress on understanding complex networks over the past decade, little is known about the regularities governing the microdynamics of social networks. Here, we explore the dynamic social network of a densely-connected population of ∼1,000 individuals and their interactions in the network of real-world person-to-person proximity measured via Bluetooth, as well as their telecommunication networks, online social media contacts, geolocation, and demographic data. These high-resolution data allow us to observe social groups directly, rendering community detection unnecessary. Starting from 5-min time slices, we uncover dynamic social structures expressed on multiple timescales. On the hourly timescale, we find that gatherings are fluid, with members coming and going, but organized via a stable core of individuals. Each core represents a social context. Cores exhibit a pattern of recurring meetings across weeks and months, each with varying degrees of regularity. Taken together, these findings provide a powerful simplification of the social network, where cores represent fundamental structures expressed with strong temporal and spatial regularity. Using this framework, we explore the complex interplay between social and geospatial behavior, documenting how the formation of cores is preceded by coordination behavior in the communication networks and demonstrating that social behavior can be predicted with high precision. PMID:27555584

  8. Quantifying long-term evolution of intra-urban spatial interactions

    PubMed Central

    Sun, Lijun; Jin, Jian Gang; Axhausen, Kay W.; Lee, Der-Horng; Cebrian, Manuel

    2015-01-01

    Understanding the long-term impact that changes in a city's transportation infrastructure have on its spatial interactions remains a challenge. The difficulty arises from the fact that the real impact may not be revealed in static or aggregated mobility measures, as these are remarkably robust to perturbations. More generally, the lack of longitudinal, cross-sectional data demonstrating the evolution of spatial interactions at a meaningful urban scale also hinders us from evaluating the sensitivity of movement indicators, limiting our capacity to understand the evolution of urban mobility in depth. Using very large mobility records distributed over 3 years, we quantify the impact of the completion of a metro line extension: the Circle Line (CCL) in Singapore. We find that the commonly used movement indicators are almost identical before and after the project was completed. However, in comparing the temporal community structure across years, we do observe significant differences in the spatial reorganization of the affected geographical areas. The completion of CCL enables travellers to re-identify their desired destinations collectively with lower transport cost, making the community structure more consistent. These changes in locality are dynamic and characterized over short timescales, offering us a different approach to identify and analyse the long-term impact of new infrastructures on cities and their evolution dynamics. PMID:25551142

  9. Novel ultra-short and ultra-broadband polarization beam splitter based on a bent directional coupler.

    PubMed

    Dai, Daoxin; Bowers, John E

    2011-09-12

    A novel ultra-short polarization beam splitter (PBS) based on a bent directional coupler is proposed by utilizing the evanescent coupling between two bent optical waveguides with different core widths. For the bent directional coupler, there is a significant phase-mismatch for TE polarization while the phase-matching condition is satisfied for TM polarization. Therefore, the TM polarized light can be coupled from the narrow input waveguide to the adjacent wide waveguide while the TE polarization goes through the coupling region without significant coupling. An ultra-short (<10 μm-long) PBS is designed based on silicon-on-insulator nanowires and the length of the bent coupling region is as small as 4.5 μm while the gap width is chosen as 200 nm (large enough to simplify the fabrication). Numerical simulations show that the present PBS has a good fabrication tolerance for the variation of the waveguide width (more than ± 60 nm) and a very broad band (~200 nm) for an extinction ratio of >10 dB.

  10. Informing Carbon Dynamics in the Community Land Model with Observations from Across Timescales

    NASA Astrophysics Data System (ADS)

    Fox, A. M.; Hoar, T. J.

    2014-12-01

    Correct simulation of carbon dynamics in Earth System Models is required to accurately predict both short and long-term land carbon-cycle climate and concentration feedbacks. As new model structures and parameterizations of increasing complexity are introduced there is an ever present need for data to inform these developments, either indirectly through benchmarking activities, or directly through model-data fusion techniques. Here we briefly describe a very rich source of data that will come from the National Ecological Observatory Network (NEON), a continental-scale facility that will collect freely available biogeochemical and biophysical data from 60 sites representative of a full range of ecosystems across the USA over 30 years. Relevant data at each site include a full suite of micrometeorology measurements, profiles of CO2 and H2O vapor isotopes, soil temperature, moisture and CO2 flux, fine root images, and plot-based NPP, leaf area and litterfall estimates. This is accompanied by Lidar and hyperspectral derived biomass, leaf area and canopy chemistry at < 1m resolution of 100s km2. Critically, these observations are well calibrated and highly standardized across sites allowing comparisons, whilst plot and site selection has been designed to optimize representativeness and spatial scaling opportunities. To illustrate the potential utility of these data in constraining models, we show the range of Community Land Model (CLM) output at NEON site locations, and in model-space look at a number of different functional responses that characterize the model in space and time and could be tested with data. These observations can be used most directly through a data assimilation (DA) system and we demonstrate how we have developed support for CLM within the Data Assimilation Research Testbed (DART) that uses ensemble techniques for state estimation. Using an observing system experiment, we investigate how infrequent observations of carbon stocks constrain model

  11. Elastically driven intermittent microscopic dynamics in soft solids

    NASA Astrophysics Data System (ADS)

    Bouzid, Mehdi; Colombo, Jader; Barbosa, Lucas Vieira; Del Gado, Emanuela

    2017-06-01

    Soft solids with tunable mechanical response are at the core of new material technologies, but a crucial limit for applications is their progressive aging over time, which dramatically affects their functionalities. The generally accepted paradigm is that such aging is gradual and its origin is in slower than exponential microscopic dynamics, akin to the ones in supercooled liquids or glasses. Nevertheless, time- and space-resolved measurements have provided contrasting evidence: dynamics faster than exponential, intermittency and abrupt structural changes. Here we use 3D computer simulations of a microscopic model to reveal that the timescales governing stress relaxation, respectively, through thermal fluctuations and elastic recovery are key for the aging dynamics. When thermal fluctuations are too weak, stress heterogeneities frozen-in upon solidification can still partially relax through elastically driven fluctuations. Such fluctuations are intermittent, because of strong correlations that persist over the timescale of experiments or simulations, leading to faster than exponential dynamics.

  12. Direct Measure of Radiative and Dynamical Properties of an Exoplanet Atmosphere

    NASA Astrophysics Data System (ADS)

    de Wit, Julien; Lewis, Nikole K.; Langton, Jonathan; Laughlin, Gregory; Deming, Drake; Batygin, Konstantin; Fortney, Jonathan J.

    2016-04-01

    Two decades after the discovery of 51 Peg b, the formation processes and atmospheres of short-period gas giants remain poorly understood. Observations of eccentric systems provide key insights on those topics as they can illuminate how a planet’s atmosphere responds to changes in incident flux. We report here the analysis of multi-day multi-channel photometry of the eccentric (e∼ 0.93) hot Jupiter HD 80606 b obtained with the Spitzer Space Telescope. The planet’s extreme eccentricity combined with the long coverage and exquisite precision of new periastron-passage observations allow us to break the degeneracy between the radiative and dynamical timescales of HD 80606 b’s atmosphere and constrain its global thermal response. Our analysis reveals that the atmospheric layers probed heat rapidly (∼4 hr radiative timescale) from \\lt 500 to 1400 K as they absorb ∼ 20% of the incoming stellar flux during the periastron passage, while the planet’s rotation period is {93}-35+85 hr, which exceeds the predicted pseudo-synchronous period (40 hr).

  13. Characterisation of seasonal flood types according to timescales in mixed probability distributions

    NASA Astrophysics Data System (ADS)

    Fischer, Svenja; Schumann, Andreas; Schulte, Markus

    2016-08-01

    When flood statistics are based on annual maximum series (AMS), the sample often contains flood peaks, which differ in their genesis. If the ratios among event types change over the range of observations, the extrapolation of a probability distribution function (pdf) can be dominated by a majority of events that belong to a certain flood type. If this type is not typical for extraordinarily large extremes, such an extrapolation of the pdf is misleading. To avoid this breach of the assumption of homogeneity, seasonal models were developed that differ between winter and summer floods. We show that a distinction between summer and winter floods is not always sufficient if seasonal series include events with different geneses. Here, we differentiate floods by their timescales into groups of long and short events. A statistical method for such a distinction of events is presented. To demonstrate their applicability, timescales for winter and summer floods in a German river basin were estimated. It is shown that summer floods can be separated into two main groups, but in our study region, the sample of winter floods consists of at least three different flood types. The pdfs of the two groups of summer floods are combined via a new mixing model. This model considers that information about parallel events that uses their maximum values only is incomplete because some of the realisations are overlaid. A statistical method resulting in an amendment of statistical parameters is proposed. The application in a German case study demonstrates the advantages of the new model, with specific emphasis on flood types.

  14. GPS in dynamic monitoring of long-period structures

    USGS Publications Warehouse

    Celebi, M.

    2000-01-01

    Global Positioning System (GPS) technology with high sampling rates (??? 10 samples per second) allows scientifically justified and economically feasible dynamic measurements of relative displacements of long-period structures-otherwise difficult to measure directly by other means, such as the most commonly used accelerometers that require post-processing including double integration. We describe an experiment whereby the displacement responses of a simulated tall building are measured clearly and accurately in real-time. Such measurements can be used to assess average drift ratios and changes in dynamic characteristics, and therefore can be used by engineers and building owners or managers to assess the building performance during extreme motions caused by earthquakes and strong winds. By establishing threshold displacements or drift ratios and identifying changing dynamic characteristics, procedures can be developed to use such information to secure public safety and/or take steps to improve the performance of the building. Published by Elsevier Science Ltd.

  15. A flexible 3D nitrogen-doped carbon foam@CNTs hybrid hosting TiO2 nanoparticles as free-standing electrode for ultra-long cycling lithium-ion batteries

    NASA Astrophysics Data System (ADS)

    Yuan, Wei; Wang, Boya; Wu, Hao; Xiang, Mingwu; Wang, Qiong; Liu, Heng; Zhang, Yun; Liu, Huakun; Dou, Shixue

    2018-03-01

    Free-standing electrodes have stood out from the electrode pack, owing to their advantage of abandoning the conventional polymeric binder and conductive agent, thus increasing the specific capacity of lithium-ion batteries. Nevertheless, their practical application is hampered by inferior electrical conductivity and complex manufacturing process. To this end, we report here a facile approach to fabricate a flexible 3D N-doped carbon foam/carbon nanotubes (NCF@CNTs) hybrid to act as the current collector and host scaffold for TiO2 particles, which are integrated into a lightweight free-standing electrode (NCF@CNTs-TiO2). In the resulting architecture, ultra-fine TiO2 nanoparticles are homogeneously anchored in situ into the N-doped NCF@CNTs framework with macro- and meso-porous structure, wrapped by a dense CNT layer, cooperatively enhances the electrode flexibility and forms an interconnected conductive network for electron/ion transport. As a result, the as-prepared NCF@CNTs-TiO2 electrode exhibits excellent lithium storage performance with high specific capacity of 241 mAh g-1 at 1 C, superb rate capability of 145 mAh g-1 at 20 C, ultra-long cycling stability with an ultra-low capacity decay of 0.0037% per cycle over 2500 cycles, and excellent thermal stability with ∼94% capacity retention over 100 cycles at 55 °C.

  16. Fractional quantum mechanics on networks: Long-range dynamics and quantum transport

    NASA Astrophysics Data System (ADS)

    Riascos, A. P.; Mateos, José L.

    2015-11-01

    In this paper we study the quantum transport on networks with a temporal evolution governed by the fractional Schrödinger equation. We generalize the dynamics based on continuous-time quantum walks, with transitions to nearest neighbors on the network, to the fractional case that allows long-range displacements. By using the fractional Laplacian matrix of a network, we establish a formalism that combines a long-range dynamics with the quantum superposition of states; this general approach applies to any type of connected undirected networks, including regular, random, and complex networks, and can be implemented from the spectral properties of the Laplacian matrix. We study the fractional dynamics and its capacity to explore the network by means of the transition probability, the average probability of return, and global quantities that characterize the efficiency of this quantum process. As a particular case, we explore analytically these quantities for circulant networks such as rings, interacting cycles, and complete graphs.

  17. Fractional quantum mechanics on networks: Long-range dynamics and quantum transport.

    PubMed

    Riascos, A P; Mateos, José L

    2015-11-01

    In this paper we study the quantum transport on networks with a temporal evolution governed by the fractional Schrödinger equation. We generalize the dynamics based on continuous-time quantum walks, with transitions to nearest neighbors on the network, to the fractional case that allows long-range displacements. By using the fractional Laplacian matrix of a network, we establish a formalism that combines a long-range dynamics with the quantum superposition of states; this general approach applies to any type of connected undirected networks, including regular, random, and complex networks, and can be implemented from the spectral properties of the Laplacian matrix. We study the fractional dynamics and its capacity to explore the network by means of the transition probability, the average probability of return, and global quantities that characterize the efficiency of this quantum process. As a particular case, we explore analytically these quantities for circulant networks such as rings, interacting cycles, and complete graphs.

  18. Astronomical calibration of the geological timescale: closing the middle Eocene gap

    NASA Astrophysics Data System (ADS)

    Westerhold, T.; Röhl, U.; Frederichs, T.; Bohaty, S. M.; Zachos, J. C.

    2015-09-01

    To explore cause and consequences of past climate change, very accurate age models such as those provided by the astronomical timescale (ATS) are needed. Beyond 40 million years the accuracy of the ATS critically depends on the correctness of orbital models and radioisotopic dating techniques. Discrepancies in the age dating of sedimentary successions and the lack of suitable records spanning the middle Eocene have prevented development of a continuous astronomically calibrated geological timescale for the entire Cenozoic Era. We now solve this problem by constructing an independent astrochronological stratigraphy based on Earth's stable 405 kyr eccentricity cycle between 41 and 48 million years ago (Ma) with new data from deep-sea sedimentary sequences in the South Atlantic Ocean. This new link completes the Paleogene astronomical timescale and confirms the intercalibration of radioisotopic and astronomical dating methods back through the Paleocene-Eocene Thermal Maximum (PETM, 55.930 Ma) and the Cretaceous-Paleogene boundary (66.022 Ma). Coupling of the Paleogene 405 kyr cyclostratigraphic frameworks across the middle Eocene further paves the way for extending the ATS into the Mesozoic.

  19. On which timescales do gas transfer velocities control North Atlantic CO2 flux variability?

    NASA Astrophysics Data System (ADS)

    Couldrey, Matthew; Oliver, Kevin; Yool, Andrew; Halloran, Paul; Achterberg, Eric

    2016-04-01

    The North Atlantic is an important basin for the global ocean's uptake of anthropogenic and natural carbon dioxide (CO2), but the mechanisms controlling this carbon flux are not fully understood. The air-sea flux of CO2, F, is the product of a gas transfer velocity, k, the air-sea CO2concentration gradient, ΔpCO2, and the temperature and salinity-dependent solubility coefficient, α. k is difficult to constrain, representing the dominant uncertainty in F on short (instantaneous to interannual) timescales. Previous work shows that in the North Atlantic, ΔpCO2and k both contribute significantly to interannual F variability, but that k is unimportant for multidecadal variability. On some timescale between interannual and multidecadal, gas transfer velocity variability and its associated uncertainty become negligible. Here, we quantify this critical timescale for the first time. Using an ocean model, we determine the importance of k, ΔpCO2and α on a range of timescales. On interannual and shorter timescales, both ΔpCO2and k are important controls on F. In contrast, pentadal to multidecadal North Atlantic flux variability is driven almost entirely by ΔpCO2; k contributes less than 25%. Finally, we explore how accurately one can estimate North Atlantic F without a knowledge of non-seasonal k variability, finding it possible for interannual and longer timescales. These findings suggest that continued efforts to better constrain gas transfer velocities are necessary to quantify interannual variability in the North Atlantic carbon sink. However, uncertainty in k variability is unlikely to limit the accuracy of estimates of longer term flux variability.

  20. On which timescales do gas transfer velocities control North Atlantic CO2 flux variability?

    NASA Astrophysics Data System (ADS)

    Couldrey, Matthew P.; Oliver, Kevin I. C.; Yool, Andrew; Halloran, Paul R.; Achterberg, Eric P.

    2016-05-01

    The North Atlantic is an important basin for the global ocean's uptake of anthropogenic and natural carbon dioxide (CO2), but the mechanisms controlling this carbon flux are not fully understood. The air-sea flux of CO2, F, is the product of a gas transfer velocity, k, the air-sea CO2 concentration gradient, ΔpCO2, and the temperature- and salinity-dependent solubility coefficient, α. k is difficult to constrain, representing the dominant uncertainty in F on short (instantaneous to interannual) timescales. Previous work shows that in the North Atlantic, ΔpCO2 and k both contribute significantly to interannual F variability but that k is unimportant for multidecadal variability. On some timescale between interannual and multidecadal, gas transfer velocity variability and its associated uncertainty become negligible. Here we quantify this critical timescale for the first time. Using an ocean model, we determine the importance of k, ΔpCO2, and α on a range of timescales. On interannual and shorter timescales, both ΔpCO2 and k are important controls on F. In contrast, pentadal to multidecadal North Atlantic flux variability is driven almost entirely by ΔpCO2; k contributes less than 25%. Finally, we explore how accurately one can estimate North Atlantic F without a knowledge of nonseasonal k variability, finding it possible for interannual and longer timescales. These findings suggest that continued efforts to better constrain gas transfer velocities are necessary to quantify interannual variability in the North Atlantic carbon sink. However, uncertainty in k variability is unlikely to limit the accuracy of estimates of longer-term flux variability.

  1. On which timescales do gas transfer velocities control North Atlantic CO2 flux variability?

    NASA Astrophysics Data System (ADS)

    Couldrey, M.; Oliver, K. I. C.; Yool, A.; Halloran, P. R.; Achterberg, E. P.

    2016-02-01

    The North Atlantic is an important basin for the global ocean's uptake of anthropogenic and natural carbon dioxide (CO2), but the mechanisms controlling this carbon flux are not fully understood. The air-sea flux of CO2, F, is the product of a gas transfer velocity, k, the air-sea CO2 concentration gradient, ΔpCO2, and the temperature and salinity-dependent solubility coefficient, α. k is difficult to constrain, representing the dominant uncertainty in F on short (instantaneous to interannual) timescales. Previous work shows that in the North Atlantic, ΔpCO2 and k both contribute significantly to interannual F variability, but that k is unimportant for multidecadal variability. On some timescale between interannual and multidecadal, gas transfer velocity variability and its associated uncertainty become negligible. Here, we quantify this critical timescale for the first time. Using an ocean model, we determine the importance of k, ΔpCO2 and α on a range of timescales. On interannual and shorter timescales, both ΔpCO2 and k are important controls on F. In contrast, pentadal to multidecadal North Atlantic flux variability is driven almost entirely by ΔpCO2; k contributes less than 25%. Finally, we explore how accurately one can estimate North Atlantic F without a knowledge of non-seasonal k variability, finding it possible for interannual and longer timescales. These findings suggest that continued efforts to better constrain gas transfer velocities are necessary to quantify interannual variability in the North Atlantic carbon sink. However, uncertainty in k variability is unlikely to limit the accuracy of estimates of longer term flux variability.

  2. Structure and dynamics of proflavine association around DNA.

    PubMed

    Sasikala, Wilbee D; Mukherjee, Arnab

    2016-04-21

    Proflavine is a small molecule that intercalates into DNA and, thereby, acts as an anticancer agent. Intercalation of proflavine is shown to be a two-step process in which the first step is believed to be the formation of a pre-intercalative outside bound state. Experimental studies so far have been unable to capture the nature of the outside bound state. However, the sub-millisecond timescale observed in fluorescence kinetic experiments is often attributed to the binding of proflavine outside of DNA. Here, we have performed molecular dynamics simulations with multiple proflavine molecules to study the structure and dynamics of the formation of the outside bound state of DNA at different ion concentrations. We observed that the timescale of the outside bound state formation is, at least, five orders of magnitude faster (in nanoseconds) than the experimentally reported timescale (sub-milliseconds) attributed to binding outside DNA. Moreover, we also observed the stacked arrangement of proflavine all around DNA, which is different from the experimentally predicted stacking arrangement perpendicular to the helical axis of DNA in the close vicinity of the phosphate groups. This study, therefore, provides insight into the molecular structure and dynamics of the pre-intercalative outside bound state and will help in understanding the overall intercalation mechanism.

  3. Ultra-fast microwave-assisted hydrothermal synthesis of long vertically aligned ZnO nanowires for dye-sensitized solar cell application.

    PubMed

    Mahpeykar, S M; Koohsorkhi, J; Ghafoori-Fard, H

    2012-04-27

    Long vertically aligned ZnO nanowire arrays were synthesized using an ultra-fast microwave-assisted hydrothermal process. Using this method, we were able to grow ZnO nanowire arrays at an average growth rate as high as 200 nm min(-1) for maximum microwave power level. This method does not suffer from the growth stoppage problem at long growth times that, according to our investigations, a normal microwave-assisted hydrothermal method suffers from. Longitudinal growth of the nanowire arrays was investigated as a function of microwave power level and growth time using cross-sectional FESEM images of the grown arrays. Effect of seed layer on the alignment of nanowires was also studied. X-ray diffraction analysis confirmed c-axis orientation and single-phase wurtzite structure of the nanowires. J-V curves of the fabricated ZnO nanowire-based mercurochrome-sensitized solar cells indicated that the short-circuit current density is increased with increasing the length of the nanowire array. According to the UV-vis spectra of the dyes detached from the cells, these increments were mainly attributed to the enlarged internal surface area and therefore dye loading enhancement in the lengthened nanowire arrays.

  4. Predictive power of the DASA-IV: Variations in rating method and timescales.

    PubMed

    Nqwaku, Mphindisi; Draycott, Simon; Aldridge-Waddon, Luke; Bush, Emma-Louise; Tsirimokou, Alexandra; Jones, Dominic; Puzzo, Ignazio

    2018-05-10

    This project evaluated the predictive validity of the Dynamic Appraisal of Situational Aggression - Inpatient Version (DASA-IV) in a high-secure psychiatric hospital in the UK over 24 hours and over a single nursing shift. DASA-IV scores from three sequential nursing shifts over a 24-hour period were compared with the mean (average of three scores across the 24-hour period) and peak (highest of the three scores across the 24-hour period) scores across these shifts. In addition, scores from a single nursing shift were used to predict aggressive incidents over each of the following three shifts. The DASA-IV was completed by nursing staff during handover meetings, rating 43 male psychiatric inpatients over a period of 6 months. Data were compared to incident reports recorded over the same period. Receiver operating characteristic (ROC) curves and generalized estimating equations assessed the predictive ability of various DASA-IV scores over 24-hour and single-shift timescales. Scores from the DASA-IV based on a single shift had moderate predictive ability for aggressive incidents occurring the next calendar day, whereas scores based on all three shifts had excellent predictive ability. DASA-IV scores from a single shift showed moderate predictive ability for each of the following three shifts. The DASA-IV has excellent predictive ability for aggressive incidents within a secure setting when data are summarized over a 24-hour period, as opposed to when a single rating is taken. In addition, it has moderate value for predicting incidents over even shorter timescales. © 2018 Australian College of Mental Health Nurses Inc.

  5. Dynamic displacement monitoring of long-span bridges with a microwave radar interferometer

    NASA Astrophysics Data System (ADS)

    Zhang, Bochen; Ding, Xiaoli; Werner, Charles; Tan, Kai; Zhang, Bin; Jiang, Mi; Zhao, Jingwen; Xu, Youlin

    2018-04-01

    Structural health monitoring of long-span bridges is a critical process in ensuring the operational safety of the structures. In this paper, we present experimental results of monitoring the displacements of two long-span bridges in Hong Kong Ting Kau Bridge (TKB) and Tsing Ma Bridge (TMB) with a terrestrial microwave radar interferometer named the GAMMA Portable Radar Interferometer (GPRI). A technique for fusing the measurements from two receiving antennas of the radar instrument is proposed. In addition, a two-step phase unwrapping approach is also tested. The results reveal the bridge dynamic responses under different loading conditions, including winds, vehicle traffic, and passing trains. The results also show that the terrestrial microwave radar interferometer can be used to monitor the dynamics of long-span bridges with unprecedented spatial and temporal resolutions.

  6. Designable ultra-smooth ultra-thin solid-electrolyte interphases of three alkali metal anodes.

    PubMed

    Gu, Yu; Wang, Wei-Wei; Li, Yi-Juan; Wu, Qi-Hui; Tang, Shuai; Yan, Jia-Wei; Zheng, Ming-Sen; Wu, De-Yin; Fan, Chun-Hai; Hu, Wei-Qiang; Chen, Zhao-Bin; Fang, Yuan; Zhang, Qing-Hong; Dong, Quan-Feng; Mao, Bing-Wei

    2018-04-09

    Dendrite growth of alkali metal anodes limited their lifetime for charge/discharge cycling. Here, we report near-perfect anodes of lithium, sodium, and potassium metals achieved by electrochemical polishing, which removes microscopic defects and creates ultra-smooth ultra-thin solid-electrolyte interphase layers at metal surfaces for providing a homogeneous environment. Precise characterizations by AFM force probing with corroborative in-depth XPS profile analysis reveal that the ultra-smooth ultra-thin solid-electrolyte interphase can be designed to have alternating inorganic-rich and organic-rich/mixed multi-layered structure, which offers mechanical property of coupled rigidity and elasticity. The polished metal anodes exhibit significantly enhanced cycling stability, specifically the lithium anodes can cycle for over 200 times at a real current density of 2 mA cm -2 with 100% depth of discharge. Our work illustrates that an ultra-smooth ultra-thin solid-electrolyte interphase may be robust enough to suppress dendrite growth and thus serve as an initial layer for further improved protection of alkali metal anodes.

  7. Dynamics of Nanoparticles in Entangled Polymer Solutions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nath, Pooja; Mangal, Rahul; Kohle, Ferdinand

    The mean square displacement < r 2 > of nanoparticle probes dispersed in simple isotropic liquids and in polymer solutions is interrogated using fluorescence correlation spectroscopy and single-particle tracking (SPT) experiments. Probe dynamics in different regimes of particle diameter (d), relative to characteristic polymer length scales, including the correlation length (ξ), the entanglement mesh size (a), and the radius of gyration (R g), are investigated. In simple fluids and for polymer solutions in which d >> R g, long-time particle dynamics obey random-walk statistics < r 2 >:t, with the bulk zero-shear viscosity of the polymer solution determining the frictionalmore » resistance to particle motion. In contrast, in polymer solutions with d < R g, polymer molecules in solution exert noncontinuum resistances to particle motion and nanoparticle probes appear to interact hydrodynamically only with a local fluid medium with effective drag comparable to that of a solution of polymer chain segments with sizes similar to those of the nanoparticle probes. Under these conditions, the nanoparticles exhibit orders of magnitude faster dynamics than those expected from continuum predictions based on the Stokes–Einstein relation. SPT measurements further show that when d > a, nanoparticle dynamics transition from diffusive to subdiffusive on long timescales, reminiscent of particle transport in a field with obstructions. This last finding is in stark contrast to the nanoparticle dynamics observed in entangled polymer melts, where X-ray photon correlation spectroscopy measurements reveal faster but hyperdiffusive dynamics. As a result, we analyze these results with the help of the hopping model for particle dynamics in polymers proposed by Cai et al. and, on that basis, discuss the physical origins of the local drag experienced by the nanoparticles in entangled polymer solutions.« less

  8. Dynamics of Nanoparticles in Entangled Polymer Solutions

    DOE PAGES

    Nath, Pooja; Mangal, Rahul; Kohle, Ferdinand; ...

    2017-12-01

    The mean square displacement < r 2 > of nanoparticle probes dispersed in simple isotropic liquids and in polymer solutions is interrogated using fluorescence correlation spectroscopy and single-particle tracking (SPT) experiments. Probe dynamics in different regimes of particle diameter (d), relative to characteristic polymer length scales, including the correlation length (ξ), the entanglement mesh size (a), and the radius of gyration (R g), are investigated. In simple fluids and for polymer solutions in which d >> R g, long-time particle dynamics obey random-walk statistics < r 2 >:t, with the bulk zero-shear viscosity of the polymer solution determining the frictionalmore » resistance to particle motion. In contrast, in polymer solutions with d < R g, polymer molecules in solution exert noncontinuum resistances to particle motion and nanoparticle probes appear to interact hydrodynamically only with a local fluid medium with effective drag comparable to that of a solution of polymer chain segments with sizes similar to those of the nanoparticle probes. Under these conditions, the nanoparticles exhibit orders of magnitude faster dynamics than those expected from continuum predictions based on the Stokes–Einstein relation. SPT measurements further show that when d > a, nanoparticle dynamics transition from diffusive to subdiffusive on long timescales, reminiscent of particle transport in a field with obstructions. This last finding is in stark contrast to the nanoparticle dynamics observed in entangled polymer melts, where X-ray photon correlation spectroscopy measurements reveal faster but hyperdiffusive dynamics. As a result, we analyze these results with the help of the hopping model for particle dynamics in polymers proposed by Cai et al. and, on that basis, discuss the physical origins of the local drag experienced by the nanoparticles in entangled polymer solutions.« less

  9. Long range personalized cancer treatment strategies incorporating evolutionary dynamics.

    PubMed

    Yeang, Chen-Hsiang; Beckman, Robert A

    2016-10-22

    Current cancer precision medicine strategies match therapies to static consensus molecular properties of an individual's cancer, thus determining the next therapeutic maneuver. These strategies typically maintain a constant treatment while the cancer is not worsening. However, cancers feature complicated sub-clonal structure and dynamic evolution. We have recently shown, in a comprehensive simulation of two non-cross resistant therapies across a broad parameter space representing realistic tumors, that substantial improvement in cure rates and median survival can be obtained utilizing dynamic precision medicine strategies. These dynamic strategies explicitly consider intratumoral heterogeneity and evolutionary dynamics, including predicted future drug resistance states, and reevaluate optimal therapy every 45 days. However, the optimization is performed in single 45 day steps ("single-step optimization"). Herein we evaluate analogous strategies that think multiple therapeutic maneuvers ahead, considering potential outcomes at 5 steps ahead ("multi-step optimization") or 40 steps ahead ("adaptive long term optimization (ALTO)") when recommending the optimal therapy in each 45 day block, in simulations involving both 2 and 3 non-cross resistant therapies. We also evaluate an ALTO approach for situations where simultaneous combination therapy is not feasible ("Adaptive long term optimization: serial monotherapy only (ALTO-SMO)"). Simulations utilize populations of 764,000 and 1,700,000 virtual patients for 2 and 3 drug cases, respectively. Each virtual patient represents a unique clinical presentation including sizes of major and minor tumor subclones, growth rates, evolution rates, and drug sensitivities. While multi-step optimization and ALTO provide no significant average survival benefit, cure rates are significantly increased by ALTO. Furthermore, in the subset of individual virtual patients demonstrating clinically significant difference in outcome between

  10. Discovery of Short-Timescale Oscillations in the Transition Region by CLASP

    NASA Technical Reports Server (NTRS)

    Kubo, M.; Katsukawa, Y.; Kano, R.; Winebarger, A.; Kobayashi, K.; Ishikawa, R.; Narukage, N.; Bando, T.; Suematsu, Y.; Giono, G.; hide

    2017-01-01

    High cadence spectroscopic observations by CLASP reveal that intensity fluctuations of blue and red peaks of the hydrogen Lyman-alpha line (121.57 nm) recurrently appear in the quiet Sun at short timescale. The intensity fluctuations of the blue and red peaks are opposite in phase to each other: the blue peak is enhanced during the decease of the red peak, and vice versa. Similar intensity fluctuations also can be seen in Mg II h & k profiles observed with IRIS. It is suggested that the short-timescale oscillatory or torsional phenomena take place in the transition region or the upper chromosphere.

  11. Wind Power Forecasting Error Distributions over Multiple Timescales: Preprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hodge, B. M.; Milligan, M.

    2011-03-01

    In this paper, we examine the shape of the persistence model error distribution for ten different wind plants in the ERCOT system over multiple timescales. Comparisons are made between the experimental distribution shape and that of the normal distribution.

  12. Structural Mechanics and Dynamics Branch

    NASA Technical Reports Server (NTRS)

    Stefko, George

    2003-01-01

    The 2002 annual report of the Structural Mechanics and Dynamics Branch reflects the majority of the work performed by the branch staff during the 2002 calendar year. Its purpose is to give a brief review of the branch s technical accomplishments. The Structural Mechanics and Dynamics Branch develops innovative computational tools, benchmark experimental data, and solutions to long-term barrier problems in the areas of propulsion aeroelasticity, active and passive damping, engine vibration control, rotor dynamics, magnetic suspension, structural mechanics, probabilistics, smart structures, engine system dynamics, and engine containment. Furthermore, the branch is developing a compact, nonpolluting, bearingless electric machine with electric power supplied by fuel cells for future "more electric" aircraft. An ultra-high-power-density machine that can generate projected power densities of 50 hp/lb or more, in comparison to conventional electric machines, which generate usually 0.2 hp/lb, is under development for application to electric drives for propulsive fans or propellers. In the future, propulsion and power systems will need to be lighter, to operate at higher temperatures, and to be more reliable in order to achieve higher performance and economic viability. The Structural Mechanics and Dynamics Branch is working to achieve these complex, challenging goals.

  13. Eruption and emplacement timescales of ignimbrite super-eruptions from thermo-kinetics of glass shards

    NASA Astrophysics Data System (ADS)

    Lavallée, Yan; Wadsworth, Fabian; Vasseur, Jérémie; Russell, James; Andrews, Graham; Hess, Kai-Uwe; von Aulock, Felix; Kendrick, Jackie; Tuffen, Hugh; Biggin, Andy; Dingwell, Donald

    2015-02-01

    Super-eruptions generating hundreds of cubic kilometres of pyroclastic density currents are commonly recorded by thick, welded and lava-like ignimbrites. Despite the huge environmental impact inferred for this type of eruption, little is yet known about the timescales of deposition and post-depositional flow. Without these timescales, the critical question of the duration of any environmental impact, and the ensuing gravity of its effects for the Earth system, eludes us. The eruption and welding of ignimbrites requires three transects of the glass transition. Magma needs to: 1) fragment during ascent, 2) liquefy and relax during deposition, agglutination and welding (sintering), and 3) quench by cooling into the glassy state. Here we show that welding is a rapid, syn-depositional process and that the welded ignimbrite sheet may flow for up to a few hours before passing through the glass transition a final time. Geospeedometry reveals that the basal vitrophyre of the Grey’s Landing ignimbrite underwent the glass transition at a rate of ~0.1 °C.min^-1 at 870 °C; that is, 30-180 °C below pre-eruptive geothermometric estimates. Application of a 1-D cooling model constrains the timescale of deposition, agglutination, and welding of the basal vitrophyre to less than 1 hour, and possibly even tens of minutes. Thermo-mechanical iteration of the sintering process indicates an optimal temperature solution for the emplacement of the vitrophyres at 966 °C. The vitrophyres reveal a Newtonian rheology up to 46 MPa, which suggests that the ash particles annealed entirely during welding and that viscous energy dissipation is unlikely from loading conditions alone, unless shear stresses imposed by the overlying ash flow were excessively high and sustained over long distances. The findings underline the value of the term 'lava-like' flow to describe the end rheology of Snake River-type ignimbrites, fully consistent with the typical lithofacies observed.

  14. Long-term neural and physiological phenotyping of a single human

    PubMed Central

    Poldrack, Russell A.; Laumann, Timothy O.; Koyejo, Oluwasanmi; Gregory, Brenda; Hover, Ashleigh; Chen, Mei-Yen; Gorgolewski, Krzysztof J.; Luci, Jeffrey; Joo, Sung Jun; Boyd, Ryan L.; Hunicke-Smith, Scott; Simpson, Zack Booth; Caven, Thomas; Sochat, Vanessa; Shine, James M.; Gordon, Evan; Snyder, Abraham Z.; Adeyemo, Babatunde; Petersen, Steven E.; Glahn, David C.; Reese Mckay, D.; Curran, Joanne E.; Göring, Harald H. H.; Carless, Melanie A.; Blangero, John; Dougherty, Robert; Leemans, Alexander; Handwerker, Daniel A.; Frick, Laurie; Marcotte, Edward M.; Mumford, Jeanette A.

    2015-01-01

    Psychiatric disorders are characterized by major fluctuations in psychological function over the course of weeks and months, but the dynamic characteristics of brain function over this timescale in healthy individuals are unknown. Here, as a proof of concept to address this question, we present the MyConnectome project. An intensive phenome-wide assessment of a single human was performed over a period of 18 months, including functional and structural brain connectivity using magnetic resonance imaging, psychological function and physical health, gene expression and metabolomics. A reproducible analysis workflow is provided, along with open access to the data and an online browser for results. We demonstrate dynamic changes in brain connectivity over the timescales of days to months, and relations between brain connectivity, gene expression and metabolites. This resource can serve as a testbed to study the joint dynamics of human brain and metabolic function over time, an approach that is critical for the development of precision medicine strategies for brain disorders. PMID:26648521

  15. 700 F hybrid capacitors cells composed of activated carbon and Li4Ti5O12 microspheres with ultra-long cycle life

    NASA Astrophysics Data System (ADS)

    Ruan, Dianbo; Kim, Myeong-Seong; Yang, Bin; Qin, Jun; Kim, Kwang-Bum; Lee, Sang-Hyun; Liu, Qiuxiang; Tan, Lei; Qiao, Zhijun

    2017-10-01

    To address the large-scale application demands of high energy density, high power density, and long cycle lifetime, 700-F hybrid capacitor pouch cells have been prepared, comprising ∼240-μm-thick activated carbon cathodes, and ∼60-μm-thick Li4Ti5O12 anodes. Microspherical Li4Ti5O12 (M-LTO) synthesized by spray-drying features 200-400 nm primary particles and interconnected nanopore structures. M-LTO half-cells exhibits high specific capacities (175 mAhh g-1), good rate capabilities (148 mAhh g-1 at 20 C), and ultra-long cycling stabilities (90% specific capacity retention after 10,000 cycles). In addition, the obtained hybrid capacitors comprising activated carbon (AC) and M-LTO shows excellent cell performances, achieving a maximum energy density of 51.65 Wh kg-1, a maximum power density of 2466 W kg-1, and ∼92% capacitance retention after 10,000 cycles, thus meeting the demands for large-scale applications such as trolleybuses.

  16. A Review of Enhanced Sampling Approaches for Accelerated Molecular Dynamics

    NASA Astrophysics Data System (ADS)

    Tiwary, Pratyush; van de Walle, Axel

    Molecular dynamics (MD) simulations have become a tool of immense use and popularity for simulating a variety of systems. With the advent of massively parallel computer resources, one now routinely sees applications of MD to systems as large as hundreds of thousands to even several million atoms, which is almost the size of most nanomaterials. However, it is not yet possible to reach laboratory timescales of milliseconds and beyond with MD simulations. Due to the essentially sequential nature of time, parallel computers have been of limited use in solving this so-called timescale problem. Instead, over the years a large range of statistical mechanics based enhanced sampling approaches have been proposed for accelerating molecular dynamics, and accessing timescales that are well beyond the reach of the fastest computers. In this review we provide an overview of these approaches, including the underlying theory, typical applications, and publicly available software resources to implement them.

  17. Dynamical model of long-term synaptic plasticity

    PubMed Central

    Abarbanel, Henry D. I.; Huerta, R.; Rabinovich, M. I.

    2002-01-01

    Long-term synaptic plasticity leading to enhancement in synaptic efficacy (long-term potentiation, LTP) or decrease in synaptic efficacy (long-term depression, LTD) is widely regarded as underlying learning and memory in nervous systems. LTP and LTD at excitatory neuronal synapses are observed to be induced by precise timing of pre- and postsynaptic events. Modification of synaptic transmission in long-term plasticity is a complex process involving many pathways; for example, it is also known that both forms of synaptic plasticity can be induced by various time courses of Ca2+ introduction into the postsynaptic cell. We present a phenomenological description of a two-component process for synaptic plasticity. Our dynamical model reproduces the spike time-dependent plasticity of excitatory synapses as a function of relative timing between pre- and postsynaptic events, as observed in recent experiments. The model accounts for LTP and LTD when the postsynaptic cell is voltage clamped and depolarized (LTP) or hyperpolarized (LTD) and no postsynaptic action potentials are evoked. We are also able to connect our model with the Bienenstock, Cooper, and Munro rule. We give model predictions for changes in synaptic strength when periodic spike trains of varying frequency and Poisson distributed spike trains with varying average frequency are presented pre- and postsynaptically. When the frequency of spike presentation exceeds ≈30–40 Hz, only LTP is induced. PMID:12114531

  18. Genetically Encoded Calcium Indicators For Studying Long-Term Calcium Dynamics During Apoptosis

    PubMed Central

    Garcia, M. Iveth; Chen, Jessica J.; Boehning, Darren

    2017-01-01

    Intracellular calcium release is essential for regulating almost all cellular functions. Specific spatio-temporal patterns of cytosolic calcium elevations are critical determinants of cell fate in response to pro-apoptotic cellular stressors. As the apoptotic program can take hours or days, measurement of long-term calcium dynamics are essential for understanding the mechanistic role of calcium in apoptotic cell death. Due to the technical limitations of using calcium-sensitive dyes to measure cytosolic calcium little is known about long-term calcium dynamics in living cells after treatment with apoptosis-inducing drugs. Genetically encoded calcium indicators could potentially overcome some of the limitations of calcium-sensitive dyes. Here, we compared the performance of the genetically encoded calcium indicators GCaMP6s and GCaMP6f with the ratiometric dye Fura-2. GCaMP6s performed as well or better than Fura-2 in detecting agonist-induced calcium transients. We then examined the utility of GCaMP6s for continuously measuring apoptotic calcium release over the course of ten hours after treatment with staurosporine. We found that GCaMP6s was suitable for measuring apoptotic calcium release over long time courses and revealed significant heterogeneity in calcium release dynamics in individual cells challenged with staurosporine. Our results suggest GCaMP6s is an excellent indicator for monitoring long-term changes cytosolic calcium during apoptosis. PMID:28073595

  19. Functional Domain Motions in Proteins on the ∼1–100 ns Timescale: Comparison of Neutron Spin-Echo Spectroscopy of Phosphoglycerate Kinase with Molecular-Dynamics Simulation

    PubMed Central

    Smolin, N.; Biehl, R.; Kneller, G.R.; Richter, D.; Smith, J.C.

    2012-01-01

    Protein function often requires large-scale domain motion. An exciting new development in the experimental characterization of domain motions in proteins is the application of neutron spin-echo spectroscopy (NSE). NSE directly probes coherent (i.e., pair correlated) scattering on the ∼1–100 ns timescale. Here, we report on all-atom molecular-dynamics (MD) simulation of a protein, phosphoglycerate kinase, from which we calculate small-angle neutron scattering (SANS) and NSE scattering properties. The simulation-derived and experimental-solution SANS results are in excellent agreement. The contributions of translational and rotational whole-molecule diffusion to the simulation-derived NSE and potential problems in their estimation are examined. Principal component analysis identifies types of domain motion that dominate the internal motion's contribution to the NSE signal, with the largest being classic hinge bending. The associated free-energy profiles are quasiharmonic and the frictional properties correspond to highly overdamped motion. The amplitudes of the motions derived by MD are smaller than those derived from the experimental analysis, and possible reasons for this difference are discussed. The MD results confirm that a significant component of the NSE arises from internal dynamics. They also demonstrate that the combination of NSE with MD is potentially useful for determining the forms, potentials of mean force, and time dependence of functional domain motions in proteins. PMID:22404933

  20. Diaphragm based long cavity Fabry-Perot fiber acoustic sensor using phase generated carrier

    NASA Astrophysics Data System (ADS)

    Liu, Bin; Lin, Jie; Liu, Huan; Ma, Yuan; Yan, Lei; Jin, Peng

    2017-01-01

    A diaphragm based long cavity Fabry-Perot interferometric fiber acoustic sensor is proposed. The Fabry-Perot cavity is formed by a flat fiber facet and an ultra-thin silver diaphragm with a 6-meter long fiber inserted in the cavity. A narrow-linewidth ring-cavity erbium-doped fiber laser is applied to demodulate the sensing signal in the phase generated carrier algorithm. Experimental results have demonstrated that the phase sensitivity is about -140 dB re 1 rad/μPa at 2 kHz. The noise equivalent acoustic signal level is 60.6 μPa/Hz1/2 and the dynamic range is 65.1 dB-SPL at 2 kHz. The sensor is suitable for sensing of weak acoustic signals.

  1. Analog quantum simulation of the Rabi model in the ultra-strong coupling regime.

    PubMed

    Braumüller, Jochen; Marthaler, Michael; Schneider, Andre; Stehli, Alexander; Rotzinger, Hannes; Weides, Martin; Ustinov, Alexey V

    2017-10-03

    The quantum Rabi model describes the fundamental mechanism of light-matter interaction. It consists of a two-level atom or qubit coupled to a quantized harmonic mode via a transversal interaction. In the weak coupling regime, it reduces to the well-known Jaynes-Cummings model by applying a rotating wave approximation. The rotating wave approximation breaks down in the ultra-strong coupling regime, where the effective coupling strength g is comparable to the energy ω of the bosonic mode, and remarkable features in the system dynamics are revealed. Here we demonstrate an analog quantum simulation of an effective quantum Rabi model in the ultra-strong coupling regime, achieving a relative coupling ratio of g/ω ~ 0.6. The quantum hardware of the simulator is a superconducting circuit embedded in a cQED setup. We observe fast and periodic quantum state collapses and revivals of the initial qubit state, being the most distinct signature of the synthesized model.An analog quantum simulation scheme has been explored with a quantum hardware based on a superconducting circuit. Here the authors investigate the time evolution of the quantum Rabi model at ultra-strong coupling conditions, which is synthesized by slowing down the system dynamics in an effective frame.

  2. Chaotic dynamics of Comet 1P/Halley: Lyapunov exponent and survival time expectancy

    NASA Astrophysics Data System (ADS)

    Muñoz-Gutiérrez, M. A.; Reyes-Ruiz, M.; Pichardo, B.

    2015-03-01

    The orbital elements of Comet Halley are known to a very high precision, suggesting that the calculation of its future dynamical evolution is straightforward. In this paper we seek to characterize the chaotic nature of the present day orbit of Comet Halley and to quantify the time-scale over which its motion can be predicted confidently. In addition, we attempt to determine the time-scale over which its present day orbit will remain stable. Numerical simulations of the dynamics of test particles in orbits similar to that of Comet Halley are carried out with the MERCURY 6.2 code. On the basis of these we construct survival time maps to assess the absolute stability of Halley's orbit, frequency analysis maps to study the variability of the orbit, and we calculate the Lyapunov exponent for the orbit for variations in initial conditions at the level of the present day uncertainties in our knowledge of its orbital parameters. On the basis of our calculations of the Lyapunov exponent for Comet Halley, the chaotic nature of its motion is demonstrated. The e-folding time-scale for the divergence of initially very similar orbits is approximately 70 yr. The sensitivity of the dynamics on initial conditions is also evident in the self-similarity character of the survival time and frequency analysis maps in the vicinity of Halley's orbit, which indicates that, on average, it is unstable on a time-scale of hundreds of thousands of years. The chaotic nature of Halley's present day orbit implies that a precise determination of its motion, at the level of the present-day observational uncertainty, is difficult to predict on a time-scale of approximately 100 yr. Furthermore, we also find that the ejection of Halley from the Solar system or its collision with another body could occur on a time-scale as short as 10 000 yr.

  3. New quasar survey with WIRO: The light curves of quasars over ~15 year timescales

    NASA Astrophysics Data System (ADS)

    Griffith, Emily; Bassett, Neil; Deam, Sophie; Dixon, Don; Harvey, William; Lee, Daniel; Lyke, Bradley; Haze Nunez, Evan; Parziale, Ryan; Witherspoon, Catherine; Myers, Adam D.; Findlay, Joseph; Kobulnicky, Henry A.; Dale, Daniel A.

    2017-01-01

    Quasars, a type of active galactic nuclei (AGN), are known to vary in brightness on 10 day to 7 year timescales. While it has been proposed that this variability is caused by instability in the accretion disk, Poisson processes, or microlensing, the exact cause remains mysterious. Understanding the physical mechanisms that drive quasar variability will require imaging of quasars over a wide range of timescales. In particular, the observations required to constrain longer timescales can be difficult to conduct. This summer ~1000 quasars in Stripe 82 were observed in ugriz wavelength bands using WIRO, the University of Wyoming’s 2.3-meter telescope. Using these images, earlier data from the Sloan Digital Sky Survey's observations of Stripe 82, as well as various data reduction methods, the quasars’ magnitude can be studied on our extended 3 day to 15 year timescale. Here, we present the light curves of ~1000 quasars in ugriz bands as observed over the last 15 years. Thiswork is supported by the National Science Foundation under REU grant AST 1560461.

  4. Design of Ultra-High-Power-Density Machine Optimized for Future Aircraft

    NASA Technical Reports Server (NTRS)

    Choi, Benjamin B.

    2004-01-01

    The NASA Glenn Research Center's Structural Mechanics and Dynamics Branch is developing a compact, nonpolluting, bearingless electric machine with electric power supplied by fuel cells for future "more-electric" aircraft with specific power in the projected range of 50 hp/lb, whereas conventional electric machines generate usually 0.2 hp/lb. The use of such electric drives for propulsive fans or propellers depends on the successful development of ultra-high-power-density machines. One possible candidate for such ultra-high-power-density machines, a round-rotor synchronous machine with an engineering current density as high as 20,000 A/sq cm, was selected to investigate how much torque and power can be produced.

  5. ULF waves: the main periodicities and their relationships with solar wind structures and magnetospheric electron flux

    NASA Astrophysics Data System (ADS)

    Piersanti, M.; Alberti, T.; Lepreti, F.; Vecchio, A.; Villante, U.; Carbone, V.; Waters, C. L.

    2015-12-01

    We use high latitude ULF wave power in the range 2-7 mHz (Pc5 geomagnetic micropulsations), solar wind speed and dynamic pressure, and relativistic magnetospheric electron flux (E > 0.6 MeV), in the period January - September 2008, in order to detect typical periodicities and physical mechanisms involved into the solar wind-magnetosphere coupling during the declining phase of the 23th solar cycle. Using the Empirical Mode Decomposition (EMD) and applying a statistical test and cross-correlation analysis,we investigate the timescales and the physical mechanisms involved into the solar wind-magnetosphere coupling.Summarizing, we obtain the following results:1. We note the existence of two different timescales into the four datasets which are related to the short-term dynamics, with a characteristic timescale τ<3 days, and to the longer timescale dynamics, with a timescale between 7 and 80 days. The short-term variations could be related to the fluctuations around a characteristic mean value, while longer timescales dynamics can be associated with solar rotational periodicity and mechanisms regarding the occurrence of high-speed streams and corotating interaction regions but also with stream-stream interactions and synodic solar rotation.2. The cross-correlation analysis highlights the relevant role of the dynamical coupling between solar wind and magnetosphere via pressure balance and direct transfer of compressional waves into the magnetosphere. Moreover, it shows that the Kelvin-Helmholtz instability is not the primary source of geomagnetic ultra-low frequency wave activity. These results are in agreement with previous works [Engebretson et al, 1998].3. The cross-correlation coefficient between Pc5 wave power and relativistic electron flux longscale reconstructions shows that Pc5 wave activity leads enhancements in magnetospheric electron flux to relativistic energy with a characteristic time delay of about 54 hours, which is in agreement with the lag of about 2

  6. Spatially dynamic recurrent information flow across long-range dorsal motor network encodes selective motor goals.

    PubMed

    Yoo, Peter E; Hagan, Maureen A; John, Sam E; Opie, Nicholas L; Ordidge, Roger J; O'Brien, Terence J; Oxley, Thomas J; Moffat, Bradford A; Wong, Yan T

    2018-06-01

    Performing voluntary movements involves many regions of the brain, but it is unknown how they work together to plan and execute specific movements. We recorded high-resolution ultra-high-field blood-oxygen-level-dependent signal during a cued ankle-dorsiflexion task. The spatiotemporal dynamics and the patterns of task-relevant information flow across the dorsal motor network were investigated. We show that task-relevant information appears and decays earlier in the higher order areas of the dorsal motor network then in the primary motor cortex. Furthermore, the results show that task-relevant information is encoded in general initially, and then selective goals are subsequently encoded in specifics subregions across the network. Importantly, the patterns of recurrent information flow across the network vary across different subregions depending on the goal. Recurrent information flow was observed across all higher order areas of the dorsal motor network in the subregions encoding for the current goal. In contrast, only the top-down information flow from the supplementary motor cortex to the frontoparietal regions, with weakened recurrent information flow between the frontoparietal regions and bottom-up information flow from the frontoparietal regions to the supplementary cortex were observed in the subregions encoding for the opposing goal. We conclude that selective motor goal encoding and execution rely on goal-dependent differences in subregional recurrent information flow patterns across the long-range dorsal motor network areas that exhibit graded functional specialization. © 2018 Wiley Periodicals, Inc.

  7. Toward understanding dynamic annealing processes in irradiated ceramics

    NASA Astrophysics Data System (ADS)

    Myers, Michael Thomas

    High energy particle irradiation inevitably generates defects in solids in the form of collision cascades. The ballistic formation and thermalization of cascades occur rapidly and are believed to be reasonably well understood. However, knowledge of the evolution of defects after damage cascade thermalization, referred to as dynamic annealing, is quite limited. Unraveling the mechanisms associated with dynamic an- nealing is crucial since such processes play an important role in the formation of stable post-irradiation disorder in ion-beam-processed semiconductors and determines the "radiation tolerance" of many nuclear materials. The purpose of this dissertation is to further our understanding of the processes involved in dynamic annealing. In order to achieve this, two main tasks are undertaken. First, the effects of dynamic annealing are investigated in ZnO, a technologically relevant material that exhibits very high dynamic defect annealing at room temper- ature. Such high dynamic annealing leads to unusual defect accumulation in heavy ion bombarded ZnO. Through this work, the puzzling features that were observed more than a decade ago in ion-channeling spectra have finally been explained. We show that the presence of a polar surface substantially alters damage accumulation. Non-polar surface terminations of ZnO are shown to exhibit enhanced dynamic an- nealing compared to polar surface terminated ZnO. Additionally, we demonstrate one method to reduce radiation damage in polar surface terminated ZnO by means of a surface modification. These results advance our efforts in the long-sought-after goal of understanding complex radiation damage processes in ceramics. Second, a pulsed-ion-beam method is developed and demonstrated in the case of Si as a prototypical non-metallic target. Such a method is shown to be a novel experimental technique for direct extraction of dynamic annealing parameters. The relaxation times and effective diffusion lengths of mobile defects

  8. Reduction of Large Dynamical Systems by Minimization of Evolution Rate

    NASA Technical Reports Server (NTRS)

    Girimaji, Sharath S.

    1999-01-01

    Reduction of a large system of equations to a lower-dimensional system of similar dynamics is investigated. For dynamical systems with disparate timescales, a criterion for determining redundant dimensions and a general reduction method based on the minimization of evolution rate are proposed.

  9. Cycles, scaling and crossover phenomenon in length of the day (LOD) time series

    NASA Astrophysics Data System (ADS)

    Telesca, Luciano

    2007-06-01

    The dynamics of the temporal fluctuations of the length of the day (LOD) time series from January 1, 1962 to November 2, 2006 were investigated. The power spectrum of the whole time series has revealed annual, semi-annual, decadal and daily oscillatory behaviors, correlated with oceanic-atmospheric processes and interactions. The scaling behavior was analyzed by using the detrended fluctuation analysis (DFA), which has revealed two different scaling regimes, separated by a crossover timescale at approximately 23 days. Flicker-noise process can describe the dynamics of the LOD time regime involving intermediate and long timescales, while Brownian dynamics characterizes the LOD time series for small timescales.

  10. Long-lived nanosecond spin relaxation and spin coherence of electrons in monolayer MoS 2 and WS 2

    DOE PAGES

    Yang, Luyi; Sinitsyn, Nikolai A.; Chen, Weibing; ...

    2015-08-03

    The recently discovered monolayer transition metal dichalcogenides (TMDCs) provide a fertile playground to explore new coupled spin–valley physics. Although robust spin and valley degrees of freedom are inferred from polarized photoluminescence (PL) experiments PL timescales are necessarily constrained by short-lived (3–100 ps) electron–hole recombination9, 10. Direct probes of spin/valley polarization dynamics of resident carriers in electron (or hole)-doped TMDCs, which may persist long after recombination ceases, are at an early stage. Here we directly measure the coupled spin–valley dynamics in electron-doped MoS 2 and WS 2 monolayers using optical Kerr spectroscopy, and reveal very long electron spin lifetimes, exceeding 3more » ns at 5 K (2-3 orders of magnitude longer than typical exciton recombination times). In contrast with conventional III–V or II–VI semiconductors, spin relaxation accelerates rapidly in small transverse magnetic fields. Supported by a model of coupled spin–valley dynamics, these results indicate a novel mechanism of itinerant electron spin dephasing in the rapidly fluctuating internal spin–orbit field in TMDCs, driven by fast inter-valley scattering. Additionally, a long-lived spin coherence is observed at lower energies, commensurate with localized states. These studies provide insight into the physics underpinning spin and valley dynamics of resident electrons in atomically thin TMDCs.« less

  11. Age, sex and (the) race: gender and geriatrics in the ultra-endurance age.

    PubMed

    Whyte, Greg

    2014-01-01

    Ultra-endurance challenges were once the stuff of legend isolated to the daring few who were driven to take on some of the greatest physical endurance challenges on the planet. With a growing fascination for major physical challenges during the nineteenth century, the end of the Victorian era witnessed probably the greatest ultra-endurance race of all time; Scott and Amundsen's ill-fated race to the South Pole. Ultra-endurance races continued through the twentieth century; however, these events were isolated to the elite few. In the twenty-first century, mass participation ultra-endurance races have grown in popularity. Endurance races once believed to be at the limit of human durability, i.e. marathon running, are now viewed as middle-distance races with the accolade of true endurance going to those willing to travel significantly further in a single effort or over multiple days. The recent series of papers in Extreme Physiology & Medicine highlights the burgeoning research data from mass participation ultra-endurance events. In support of a true 'mass participation' ethos Knetchtle et al. reported age-related changes in Triple and Deca Iron-ultra-triathlon with an upper age of 69 years! Unlike their shorter siblings, the ultra-endurance races appear to present larger gender differences in the region of 20% to 30% across distance and modality. It would appear that these gender differences remain for multi-day events including the 'Marathon des Sables'; however, this gap may be narrower in some events, particularly those that require less load bearing (i.e. swimming and cycling), as evidenced from the 'Ultraman Hawaii' and 'Swiss Cycling Marathon', and shorter (a term I used advisedly!) distances including the Ironman Triathlon where differences are similar to those of sprint and endurance distances i.e. c. 10%. The theme running through this series of papers is a continual rise in participation to the point where major events now require selection races to remain

  12. GMLC Extreme Event Modeling -- Slow-Dynamics Models for Renewable Energy Resources

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Korkali, M.; Min, L.

    The need for slow dynamics models of renewable resources in cascade modeling essentially arises from the challenges associated with the increased use of solar and wind electric power. Indeed, the main challenge is that the power produced by wind and sunlight is not consistent; thus, renewable energy resources tend to have variable output power on many different timescales, including the timescales that a cascade unfolds.

  13. Evaluating the Impact of Genomic Data and Priors on Bayesian Estimates of the Angiosperm Evolutionary Timescale.

    PubMed

    Foster, Charles S P; Sauquet, Hervê; van der Merwe, Marlien; McPherson, Hannah; Rossetto, Maurizio; Ho, Simon Y W

    2017-05-01

    The evolutionary timescale of angiosperms has long been a key question in biology. Molecular estimates of this timescale have shown considerable variation, being influenced by differences in taxon sampling, gene sampling, fossil calibrations, evolutionary models, and choices of priors. Here, we analyze a data set comprising 76 protein-coding genes from the chloroplast genomes of 195 taxa spanning 86 families, including novel genome sequences for 11 taxa, to evaluate the impact of models, priors, and gene sampling on Bayesian estimates of the angiosperm evolutionary timescale. Using a Bayesian relaxed molecular-clock method, with a core set of 35 minimum and two maximum fossil constraints, we estimated that crown angiosperms arose 221 (251-192) Ma during the Triassic. Based on a range of additional sensitivity and subsampling analyses, we found that our date estimates were generally robust to large changes in the parameters of the birth-death tree prior and of the model of rate variation across branches. We found an exception to this when we implemented fossil calibrations in the form of highly informative gamma priors rather than as uniform priors on node ages. Under all other calibration schemes, including trials of seven maximum age constraints, we consistently found that the earliest divergences of angiosperm clades substantially predate the oldest fossils that can be assigned unequivocally to their crown group. Overall, our results and experiments with genome-scale data suggest that reliable estimates of the angiosperm crown age will require increased taxon sampling, significant methodological changes, and new information from the fossil record. [Angiospermae, chloroplast, genome, molecular dating, Triassic.]. © The Author(s) 2016. Published by Oxford University Press, on behalf of the Society of Systematic Biologists. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  14. ENSO and its modulations on annual and multidecadal timescales revealed by Nonlinear Laplacian Spectral Analysis

    NASA Astrophysics Data System (ADS)

    Giannakis, D.; Slawinska, J. M.

    2016-12-01

    The variability of the Indo-Pacific Ocean on interannual to multidecadal timescales is investigated in a millennial control run of CCSM4 and in observations using a recently introduced technique called Nonlinear Laplacian Spectral Analysis (NLSA). Through this technique, drawbacks associated with ad hoc pre-filtering of the input data are avoided, enabling recovery of low-frequency and intermittent modes not accessible previously via classical approaches. Here, a multiscale hierarchy of modes is identified for Indo-Pacific SST and numerous linkages between these patterns are revealed. On interannual timescales, a mode with spatiotemporal pattern corresponding to the fundamental component of ENSO emerges, along with modulations of the annual cycle by ENSO in agreement with ENSO combination mode theory. In spatiotemporal reconstructions, these patterns capture the seasonal southward migration of SST and zonal wind anomalies associated with termination of El Niño and La Niña events. Notably, this family of modes explains a significant portion of SST variance in Eastern Indian Ocean regions employed in the definition of Indian Ocean dipole (IOD) indices, suggesting that it should be useful for understanding the linkage of these indices with ENSO and the interaction of the Indian and Pacific Oceans. In model data, we find that the ENSO and ENSO combination modes are modulated on multidecadal timescales by a mode predominantly active in the western tropical Pacific - we call this mode West Pacific Multidecadal Oscillation (WPMO). Despite the relatively low variance explained by this mode, its dynamical role appears to be significant as it has clear sign-dependent modulating relationships with the interannual modes carrying most of the variance. In particular, cold WPMO events are associated with anomalous Central Pacific westerlies favoring stronger ENSO events, while warm WPMO events suppress ENSO activity. Moreover, the WPMO has significant climatic impacts as

  15. Dynamics of bulk electron heating and ionization in solid density plasmas driven by ultra-short relativistic laser pulses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huang, L. G., E-mail: lingen.huang@hzdr.de; Kluge, T.; Cowan, T. E.

    The dynamics of bulk heating and ionization is investigated both in simulations and theory, which determines the crucial plasma parameters such as plasma temperature and density in ultra-short relativistic laser-solid target interactions. During laser-plasma interactions, the solid density plasma absorbs a fraction of laser energy and converts it into kinetic energy of electrons. A portion of the electrons with relativistic kinetic energy goes through the solid density plasma and transfers energy into the bulk electrons, which results in bulk electron heating. The bulk electron heating is finally translated into the processes of bulk collisional ionization inside the solid target. Amore » simple model based on the Ohmic heating mechanism indicates that the local and temporal profile of bulk return current is essential to determine the temporal evolution of bulk electron temperature. A series of particle-in-cell simulations showing the local heating model is robust in the cases of target with a preplasma and without a preplasma. Predicting the bulk electron heating is then benefit for understanding the collisional ionization dynamics inside the solid targets. The connection of the heating and ionization inside the solid target is further studied using Thomas-Fermi model.« less

  16. Dispersal constraints for stream invertebrates: setting realistic timescales for biodiversity restoration.

    PubMed

    Parkyn, Stephanie M; Smith, Brian J

    2011-09-01

    Biodiversity goals are becoming increasingly important in stream restoration. Typical models of stream restoration are based on the assumption that if habitat is restored then species will return and ecological processes will re-establish. However, a range of constraints at different scales can affect restoration success. Much of the research in stream restoration ecology has focused on habitat constraints, namely the in-stream and riparian conditions required to restore biota. Dispersal constraints are also integral to determining the timescales, trajectory and potential endpoints of a restored ecosystem. Dispersal is both a means of organism recolonization of restored sites and a vital ecological process that maintains viable populations. We review knowledge of dispersal pathways and explore the factors influencing stream invertebrate dispersal. From empirical and modeling studies of restoration in warm-temperate zones of New Zealand, we make predictions about the timescales of stream ecological restoration under differing levels of dispersal constraints. This process of constraints identification and timescale prediction is proposed as a practical step for resource managers to prioritize and appropriately monitor restoration sites and highlights that in some instances, natural recolonization and achievement of biodiversity goals may not occur.

  17. Dispersal Constraints for Stream Invertebrates: Setting Realistic Timescales for Biodiversity Restoration

    NASA Astrophysics Data System (ADS)

    Parkyn, Stephanie M.; Smith, Brian J.

    2011-09-01

    Biodiversity goals are becoming increasingly important in stream restoration. Typical models of stream restoration are based on the assumption that if habitat is restored then species will return and ecological processes will re-establish. However, a range of constraints at different scales can affect restoration success. Much of the research in stream restoration ecology has focused on habitat constraints, namely the in-stream and riparian conditions required to restore biota. Dispersal constraints are also integral to determining the timescales, trajectory and potential endpoints of a restored ecosystem. Dispersal is both a means of organism recolonization of restored sites and a vital ecological process that maintains viable populations. We review knowledge of dispersal pathways and explore the factors influencing stream invertebrate dispersal. From empirical and modeling studies of restoration in warm-temperate zones of New Zealand, we make predictions about the timescales of stream ecological restoration under differing levels of dispersal constraints. This process of constraints identification and timescale prediction is proposed as a practical step for resource managers to prioritize and appropriately monitor restoration sites and highlights that in some instances, natural recolonization and achievement of biodiversity goals may not occur.

  18. A Dual-Colour Architecture for Pump-Probe Spectroscopy of Ultrafast Magnetization Dynamics in the Sub-10-femtosecond Range.

    PubMed

    Gonçalves, C S; Silva, A S; Navas, D; Miranda, M; Silva, F; Crespo, H; Schmool, D S

    2016-03-15

    Current time-resolution-limited dynamic measurements clearly show the need for improved techniques to access processes on the sub-10-femtosecond timescale. To access this regime, we have designed and constructed a state-of-the-art time-resolved magneto-optic Kerr effect apparatus, based on a new dual-color scheme, for the measurement of ultrafast demagnetization and precessional dynamics in magnetic materials. This system can operate well below the current temporal ranges reported in the literature, which typically lie in the region of around 50 fs and above. We have used a dual-colour scheme, based on ultra broadband hollow-core fibre and chirped mirror pulse compression techniques, to obtain unprecedented sub-8-fs pump and probe pulse durations at the sample plane. To demonstrate the capabilities of this system for ultrafast demagnetization and precessional dynamics studies, we have performed measurements in a ferrimagnetic GdFeCo thin film. Our study has shown that the magnetization shows a sudden drop within the first picosecond after the pump pulse, a fast recovery (remagnetization) within a few picoseconds, followed by a clear oscillation or precession during a slower magnetization recovery. Moreover, we have experimentally confirmed for the first time that a sub-10-fs pulse is able to efficiently excite a magnetic system such as GdFeCo.

  19. Numerically Exact Long Time Magnetization Dynamics Near the Nonequilibrium Kondo Regime

    NASA Astrophysics Data System (ADS)

    Cohen, Guy; Gull, Emanuel; Reichman, David; Millis, Andrew; Rabani, Eran

    2013-03-01

    The dynamical and steady-state spin response of the nonequilibrium Anderson impurity model to magnetic fields, bias voltages, and temperature is investigated by a numerically exact method which allows access to unprecedentedly long times. The method is based on using real, continuous time bold Monte Carlo techniques--quantum Monte Carlo sampling of diagrammatic corrections to a partial re-summation--in order to compute the kernel of a memory function, which is then used to determine the reduced density matrix. The method owes its effectiveness to the fact that the memory kernel is dominated by relatively short-time properties even when the system's dynamics are long-ranged. We make predictions regarding the non-monotonic temperature dependence of the system at high bias voltage and the oscillatory quench dynamics at high magnetic fields. We also discuss extensions of the method to the computation of transport properties and correlation functions, and its suitability as an impurity solver free from the need for analytical continuation in the context of dynamical mean field theory. This work is supported by the US Department of Energy under grant DE-SC0006613, by NSF-DMR-1006282 and by the US-Israel Binational Science Foundation. GC is grateful to the Yad Hanadiv-Rothschild Foundation for the award of a Rothschild Fellowship.

  20. Compliance of Ultra-Orthodox and secular pedestrians with traffic lights in Ultra-Orthodox and secular locations.

    PubMed

    Rosenbloom, Tova; Shahar, Amit; Perlman, Amotz

    2008-11-01

    Following a previous study that revealed the disobedience of Ultra-Orthodox citizens, as compared to secular citizens, of traffic lights at crosswalks, the present study examined the road habits of 995 Ultra-Orthodox and secular pedestrians in neighboring Ultra-Orthodox and secular cities. Using an observation grid designed specially for this study, the pedestrians were observed at two crosswalks--one in an Ultra-Orthodox city and one in a secular city--as far as similar traffic parameters, using a logistic regression. The tendency to cross on a red light was assessed as a function of estimated age, gender, religiosity, location (religious/secular), the duration of the red light, the number of vehicles crossing and the number of pedestrians waiting at the curb. Ultra-Orthodox pedestrians committed more violations than secular pedestrians did, and there were more road violations in the Ultra-Orthodox location than there were in the secular location. Fewer traffic violations were committed by "local" pedestrians (Ultra-Orthodox pedestrians in the Ultra-Orthodox location and secular pedestrians in the secular location) than by "foreigners" (Ultra-Orthodox pedestrians in the secular location and secular pedestrians in the Ultra-Orthodox location). The odds of crossing on a red light decreased as a function of both the number of people waiting at the curb and the number of vehicles. Consistent with previous research, males crossed on red much more than females did, regardless of religiosity and location. Our discussion focuses on theoretical and practical explanations of the findings.