Fast Interrogation of Fiber Bragg Gratings with Electro-Optical Dual Optical Frequency Combs

PubMed Central

Posada-Roman, Julio E.; Garcia-Souto, Jose A.; Poiana, Dragos A.; Acedo, Pablo

2016-01-01

Optical frequency combs (OFC) generated by electro-optic modulation of continuous-wave lasers provide broadband coherent sources with high power per line and independent control of line spacing and the number of lines. In addition to their application in spectroscopy, they offer flexible and optimized sources for the interrogation of other sensors based on wavelength change or wavelength filtering, such as fiber Bragg grating (FBG) sensors. In this paper, a dual-OFC FBG interrogation system based on a single laser and two optical-phase modulators is presented. This architecture allows for the configuration of multimode optical source parameters such as the number of modes and their position within the reflected spectrum of the FBG. A direct read-out is obtained by mapping the optical spectrum onto the radio-frequency spectrum output of the dual-comb. This interrogation scheme is proposed for measuring fast phenomena such as vibrations and ultrasounds. Results are presented for dual-comb operation under optimized control. The optical modes are mapped onto detectable tones that are multiples of 0.5 MHz around a center radiofrequency tone (40 MHz). Measurements of ultrasounds (40 kHz and 120 kHz) are demonstrated with this sensing system. Ultrasounds induce dynamic strain onto the fiber, which generates changes in the reflected Bragg wavelength and, hence, modulates the amplitude of the OFC modes within the reflected spectrum. The amplitude modulation of two counterphase tones is detected to obtain a differential measurement proportional to the ultrasound signal. PMID:27898043

Fast Interrogation of Fiber Bragg Gratings with Electro-Optical Dual Optical Frequency Combs.

PubMed

Posada-Roman, Julio E; Garcia-Souto, Jose A; Poiana, Dragos A; Acedo, Pablo

2016-11-26

Optical frequency combs (OFC) generated by electro-optic modulation of continuous-wave lasers provide broadband coherent sources with high power per line and independent control of line spacing and the number of lines. In addition to their application in spectroscopy, they offer flexible and optimized sources for the interrogation of other sensors based on wavelength change or wavelength filtering, such as fiber Bragg grating (FBG) sensors. In this paper, a dual-OFC FBG interrogation system based on a single laser and two optical-phase modulators is presented. This architecture allows for the configuration of multimode optical source parameters such as the number of modes and their position within the reflected spectrum of the FBG. A direct read-out is obtained by mapping the optical spectrum onto the radio-frequency spectrum output of the dual-comb. This interrogation scheme is proposed for measuring fast phenomena such as vibrations and ultrasounds. Results are presented for dual-comb operation under optimized control. The optical modes are mapped onto detectable tones that are multiples of 0.5 MHz around a center radiofrequency tone (40 MHz). Measurements of ultrasounds (40 kHz and 120 kHz) are demonstrated with this sensing system. Ultrasounds induce dynamic strain onto the fiber, which generates changes in the reflected Bragg wavelength and, hence, modulates the amplitude of the OFC modes within the reflected spectrum. The amplitude modulation of two counterphase tones is detected to obtain a differential measurement proportional to the ultrasound signal.

Monitoring high-intensity focused ultrasound (HIFU) therapy using radio frequency ultrasound backscatter to quantify heating

NASA Astrophysics Data System (ADS)

Kaczkowski, Peter J.; Anand, Ajay

2005-09-01

The spatial distribution and temporal history of tissue temperature is an essential indicator of thermal therapy progress, and treatment safety and efficacy. Magnetic resonance methods provide the gold standard noninvasive measurement of temperature but are costly and cumbersome compared to the therapy itself. We have been developing the use of ultrasound backscattering for real-time temperature estimation; ultrasonic methods have been limited to relatively low temperature rise, primarily due to lack of sensitivity at protein denaturation temperatures (50-70°C). Through validation experiments on gel phantoms and ex vivo tissue we show that temperature rise can be accurately mapped throughout the therapeutic temperature range using a new BioHeat Transfer Equation (BHTE) model-constrained inverse approach. Speckle-free temperature and thermal dose maps are generated using the ultrasound calibrated model over the imaged region throughout therapy delivery and post-treatment cooling periods. Results of turkey breast tissue experiments are presented for static HIFU exposures, in which the ultrasound calibrated BHTE temperature maps are shown to be very accurate (within a degree) using independent thermocouple measurements. This new temperature monitoring method may speed clinical adoption of ultrasound-guided HIFU therapy. [Work supported by Army MRMC.

Conformal drug delivery and instantaneous monitoring based on an inverse synthesis method at a diagnostic ultrasound platform

NASA Astrophysics Data System (ADS)

Xu, Shanshan; Zong, Yujin; Liu, Xiaodong; Lu, Mingzhu; Wan, Mingxi

2017-03-01

In this paper, based on a programmable diagnostic ultrasound scanner, a combined approach was proposed, in which a variable-sized focal region wherein the acoustic pressure is above the ultrasound contrast agents (UCA) fragmentation threshold is synthesized by reasonably matching the excitation voltage and the transmit aperture of the linear array at 5MHz, the UCAs' temporal and spatial distribution before and after the microbubbles fragmentation is monitored using the plane-wave transmission and reception at 400Hz and, simultaneously, the broadband noise emission during the microbubbles fragmentation is extracted using the backscattering of focused release bursts (destruction pulse) themselves on the linear array. Then, acquired radio frequency (RF) data are processed to draw parameters which can be correlated with the indicator of broadband noise emission level, namely inertial cavitation dose (ICD) and microbubble fragmentation efficiency, namely decay rate of microbubbles.

Pulmonary ultrasound elastography: a feasibility study with phantoms and ex-vivo tissue

NASA Astrophysics Data System (ADS)

Nguyen, Man Minh; Xie, Hua; Paluch, Kamila; Stanton, Douglas; Ramachandran, Bharat

2013-03-01

Elastography has become widely used for minimally invasive diagnosis in many tumors as seen with breast, liver and prostate. Among different modalities, ultrasound-based elastography stands out due to its advantages including being safe, real-time, and relatively low-cost. While lung cancer is the leading cause of cancer mortality among both men and women, the use of ultrasound elastography for lung cancer diagnosis has hardly been investigated due to the limitations of ultrasound in air. In this work, we investigate the use of static-compression based endobronchial ultrasound elastography by a 3D trans-oesophageal echocardiography (TEE) transducer for lung cancer diagnosis. A water-filled balloon was designed to 1) improve the visualization of endobronchial ultrasound and 2) to induce compression via pumping motion inside the trachea and bronchiole. In a phantom study, we have successfully generated strain images indicating the stiffness difference between the gelatin background and agar inclusion. A similar strain ratio was confirmed with Philips ultrasound strain-based elastography product. For ex-vivo porcine lung study, different tissue ablation methods including chemical injection, Radio Frequency (RF) ablation, and direct heating were implemented to achieve tumor-mimicking tissue. Stiff ablated lung tissues were obtained and detected with our proposed method. These results suggest the feasibility of pulmonary elastography to differentiate stiff tumor tissue from normal tissue.

Performance Evaluation of Adaptive Imaging Based on Multiphase Apodization with Cross-correlation: A Pilot Study in Abdominal Ultrasound.

PubMed

Shin, Junseob; Chen, Yu; Malhi, Harshawn; Chen, Frank; Yen, Jesse

2018-05-01

Degradation of image contrast caused by phase aberration, off-axis clutter, and reverberation clutter remains one of the most important problems in abdominal ultrasound imaging. Multiphase apodization with cross-correlation (MPAX) is a novel beamforming technique that enhances ultrasound image contrast by adaptively suppressing unwanted acoustic clutter. MPAX employs multiple pairs of complementary sinusoidal phase apodizations to intentionally introduce grating lobes that can be used to derive a weighting matrix, which mostly preserves the on-axis signals from tissue but reduces acoustic clutter contributions when multiplied with the beamformed radio-frequency (RF) signals. In this paper, in vivo performance of the MPAX technique was evaluated in abdominal ultrasound using data sets obtained from 10 human subjects referred for abdominal ultrasound at the USC Keck School of Medicine. Improvement in image contrast was quantified, first, by the contrast-to-noise ratio (CNR) and, second, by the rating of two experienced radiologists. The MPAX technique was evaluated for longitudinal and transverse views of the abdominal aorta, the inferior vena cava, the gallbladder, and the portal vein. Our in vivo results and analyses demonstrate the feasibility of the MPAX technique in enhancing image contrast in abdominal ultrasound and show potential for creating high contrast ultrasound images with improved target detectability and diagnostic confidence.

High resolution three-dimensional robotic synthetic tracked aperture ultrasound imaging: feasibility study

NASA Astrophysics Data System (ADS)

Zhang, Haichong K.; Fang, Ting Yun; Finocchi, Rodolfo; Boctor, Emad M.

2017-03-01

Three dimensional (3D) ultrasound imaging is becoming a standard mode for medical ultrasound diagnoses. Conventional 3D ultrasound imaging is mostly scanned either by using a two dimensional matrix array or by motorizing a one dimensional array in the elevation direction. However, the former system is not widely assessable due to its cost, and the latter one has limited resolution and field-of-view in the elevation axis. Here, we propose a 3D ultrasound imaging system based on the synthetic tracked aperture approach, in which a robotic arm is used to provide accurate tracking and motion. While the ultrasound probe is moved by a robotic arm, each probe position is tracked and can be used to reconstruct a wider field-of-view as there are no physical barriers that restrict the elevational scanning. At the same time, synthetic aperture beamforming provides a better resolution in the elevation axis. To synthesize the elevational information, the single focal point is regarded as the virtual element, and forward and backward delay-andsum are applied to the radio-frequency (RF) data collected through the volume. The concept is experimentally validated using a general ultrasound phantom, and the elevational resolution improvement of 2.54 and 2.13 times was measured at the target depths of 20 mm and 110 mm, respectively.

Non-contact thermoacoustic detection of embedded targets using airborne-capacitive micromachined ultrasonic transducers

NASA Astrophysics Data System (ADS)

Nan, Hao; Boyle, Kevin C.; Apte, Nikhil; Aliroteh, Miaad S.; Bhuyan, Anshuman; Nikoozadeh, Amin; Khuri-Yakub, Butrus T.; Arbabian, Amin

2015-02-01

A radio frequency (RF)/ultrasound hybrid imaging system using airborne capacitive micromachined ultrasonic transducers (CMUTs) is proposed for the remote detection of embedded objects in highly dispersive media (e.g., water, soil, and tissue). RF excitation provides permittivity contrast, and ultra-sensitive airborne-ultrasound detection measures thermoacoustic-generated acoustic waves that initiate at the boundaries of the embedded target, go through the medium-air interface, and finally reach the transducer. Vented wideband CMUTs interface to 0.18 μm CMOS low-noise amplifiers to provide displacement detection sensitivity of 1.3 pm at the transducer surface. The carefully designed vented CMUT structure provides a fractional bandwidth of 3.5% utilizing the squeeze-film damping of the air in the cavity.

A Freehand Ultrasound Elastography System with Tracking for In-vivo Applications

PubMed Central

Foroughi, Pezhman; Kang, Hyun-Jae; Carnegie, Daniel A.; van Vledder, Mark G.; Choti, Michael A.; Hager, Gregory D.; Boctor, Emad M.

2012-01-01

Ultrasound transducers are commonly tracked in modern ultrasound navigation/guidance systems. In this paper, we demonstrate the advantages of incorporating tracking information into ultrasound elastography for clinical applications. First, we address a common limitation of freehand palpation: speckle decorrelation due to out-of-plane probe motion. We show that by automatically selecting pairs of radio frequency (RF) frames with minimal lateral and out-of-plane motions combined with a fast and robust displacement estimation technique greatly improves in-vivo elastography results. We also use tracking information and image quality measure to fuse multiple images with similar strain that are taken roughly from the same location to obtain a high quality elastography image. Finally, we show that tracking information can be used to give the user partial control over the rate of compression. Our methods are tested on tissue mimicking phantom and experiments have been conducted on intra-operative data acquired during animal and human experiments involving liver ablation. Our results suggest that in challenging clinical conditions, our proposed method produces reliable strain images and eliminates the need for a manual search through the ultrasound data in order to find RF pairs suitable for elastography. PMID:23257351

Ultrasonically modulated x-ray phase contrast and vibration potential imaging methods

NASA Astrophysics Data System (ADS)

Hamilton, Theron J.; Cao, Guohua; Wang, Shougang; Bailat, Claude J.; Nguyen, Cuong K.; Li, Shengqiong; Gehring, Stephan; Wands, Jack; Gusev, Vitalyi; Rose-Petruck, Christoph; Diebold, Gerald J.

2006-02-01

We show that the radiation pressure exerted by a beam of ultrasound can be used for contrast enhancement in high resolution x-ray imaging of tissue. Interfacial features of objects are highlighted as a result of both the displacement introduced by the ultrasound and the inherent sensitivity of x-ray phase contrast imaging to density variations. The potential of the method is demonstrated by imaging various tumor phantoms and tumors from mice. The directionality of the acoustic radiation force and its localization in space permits the imaging of ultrasound-selected tissue volumes. In a related effort we report progress on development of an imaging technique using and electrokinetic effect known as the ultrasonic vibration potential. The ultrasonic vibration potential refers to the voltage generated when ultrasound traverses a colloidal or ionic fluid. The theory of imaging based on the vibration potential is reviewed, and an expression given that describes the signal from an arbitrary object. The experimental apparatus consists of a pair of parallel plates connected to the irradiated body, a low noise preamplifier, a radio frequency lock-in amplifier, translation stages for the ultrasonic transducer that generates the ultrasound, and a computer for data storage and image formation. Experiments are reported where bursts of ultrasound are directed onto colloidal silica objects placed within inert bodies.

Radio-frequency plasma transducer for use in harsh environments.

PubMed

May, Andrew; Andarawis, Emad

2007-10-01

We describe a compact transducer used to generate and modulate low-intensity radio-frequency atmospheric pressure plasma (RF-APP) for high temperature gap measurement and generation of air-coupled ultrasound. The new transducer consists of a quarter-wave transmission line where the ground return path is a coaxial solenoid winding. The RF-APP is initiated at the open end of the transmission line and stabilized by passive negative feedback between the electrical impedance of the plasma and the energy stored in the solenoid. The electrical impedance of the plasma was measured at the lower-voltage source end of the transducer, eliminating the need to measure kilovolt-level voltages near the discharge. We describe the use of a 7 MHz RF-APP prototype as a harsh-environment clearance sensor to demonstrate the suitability of plasma discharges for a common nondestructive inspection application. Clearance measurements of 0-5 mm were performed on a rotating calibration target with a measurement precision of 0.1 mm and a 20 kHz sampling rate.

[Nonionizing radiation and electromagnetic fields].

PubMed

Bernhardt, J H

1991-01-01

Nonionising radiation comprises all kinds of radiation and fields of the electromagnetic spectrum where biological matter is not ionised, as well as mechanical waves such as infrasound and ultrasound. The electromagnetic spectrum is subdivided into individual sections and includes: Static and low-frequency electric and magnetic fields including technical applications of energy with mains frequency, radio frequency fields, microwaves and optic radiation (infrared, visible light, ultraviolet radiation including laser). The following categories of persons can be affected by emissions by non-ionising radiation: Persons in the environment and in the household, workers, patients undergoing medical diagnosis or treatment. If the radiation is sufficiently intense, or if the fields are of appropriate strength, a multitude of effects can occur (depending on the type of radiation), such as heat and stimulating or irritating action, inflammations of the skin or eyes, changes in the blood picture, burns or in some cases cancer as a late sequel. The ability of radiation to penetrate into the human body, as well as the types of interaction with biological tissue, with organs and organisms, differs significantly for the various kinds of nonionising radiation. The following aspects of nonionising radiation are discussed: protection of humans against excessive sunlight rays when sunbathing and when exposed to UV radiation (e.g. in solaria); health risks of radio and microwaves (safety of microwave cookers and mobile radio units); effects on human health by electric and magnetic fields in everyday life.

Effectiveness of advertising availability of prenatal ultrasound on uptake of antenatal care in rural Uganda: A cluster randomized trial.

PubMed

Cherniak, William; Anguyo, Geoffrey; Meaney, Christopher; Yuan Kong, Ling; Malhame, Isabelle; Pace, Romina; Sodhi, Sumeet; Silverman, Michael

2017-01-01

In rural Uganda pregnant women often lack access to health services, do not attend antenatal care, and tend to utilize traditional healers/birth attendants. We hypothesized that receiving a message advertising that "you will be able to see your baby by ultrasound" would motivate rural Ugandan women who otherwise might use a traditional birth attendant to attend antenatal care, and that those women would subsequently be more satisfied with care. A cluster randomized trial was conducted across eight rural sub-counties in southwestern Uganda. Sub-counties were randomized to a control arm, with advertisement of antenatal care with no mention of portable obstetric ultrasound (four communities, n = 59), or an intervention arm, with advertisement of portable obstetric ultrasound. Advertisement of portable obstetric ultrasound was further divided into intervention A) word of mouth advertisement of portable obstetric ultrasound and antenatal care (one communitity, n = 16), B) radio advertisement of only antenatal care and word of mouth advertisement of antenatal care and portable obstetric ultrasound (one community, n = 7), or C) word of mouth + radio advertisement of both antenatal care and portable obstetric ultrasound (two communities, n = 75). The primary outcome was attendance to antenatal care. 159 women presented to antenatal care across eight sub-counties. The rate of attendance was 65.1 (per 1000 pregnant women, 95% CI 38.3-110.4) where portable obstetric ultrasound was advertised by radio and word of mouth, as compared to a rate of 11.1 (95% CI 6.1-20.1) in control communities (rate ratio 5.9, 95% CI 2.6-13.0, p<0.0001). Attendance was also improved in women who had previously seen a traditional healer (13.0, 95% CI 5.4-31.2) compared to control (1.5, 95% CI 0.5-5.0, rate ratio 8.7, 95% CI 2.0-38.1, p = 0.004). By advertising antenatal care and portable obstetric ultrasound by radio attendance was significantly improved. This study suggests that women can be motivated to attend antenatal care when offered the concrete incentive of seeing their baby.

A new method for blood velocity measurements using ultrasound FMCW signals.

PubMed

Kunita, Masanori; Sudo, Masamitsu; Inoue, Shinya; Akahane, Mutsuhiro

2010-05-01

The low peak power of frequency-modulated continuous wave (FMCW) radar makes it attractive for various applications, including vehicle collision warning systems and airborne radio altimeters. This paper describes a new ultrasound Doppler measurement system that measures blood flow velocity based on principles similar to those of FMCW radar. We propose a sinusoidal wave for FM modulation and introduce a new demodulation technique for obtaining Doppler information with high SNR and range resolution. Doppler signals are demodulated with a reference FMCW signal to adjust delay times so that they are equal to propagation times between the transmitter and the receiver. Analytical results suggest that Doppler signals can be obtained from a selected position, as with a sample volume in pulse wave Doppler systems, and that the resulting SNR is nearly identical to that obtained with continuous wave (CW) Doppler systems. Additionally, clutter power is less than that of CW Doppler systems. The analytical results were verified by experiments involving electronic circuits and Doppler ultrasound phantoms.

Control of treatment size in cavitation-enhanced high-intensity focused ultrasound using radio-frequency echo signals

NASA Astrophysics Data System (ADS)

Tomiyasu, Kentaro; Takagi, Ryo; Iwasaki, Ryosuke; Yoshizawa, Shin; Umemura, Shin-ichiro

2017-07-01

In high-intensity focused ultrasound (HIFU) treatment, controlling the ultrasound dose at each focal target spot is important because it is a problem that the length of the coagulated region in front of the focal point deviates owing to the differences in absorption in each focal target spot and attenuation in the intervening tissues. In this study, the detected changes in the power spectra of HIFU echoes were used by controlling the HIFU duration in the “trigger HIFU” sequence with the aim to increase coagulation size through the enhancement of the ultrasonic heating by the cavitation induced by the preceding extremely high intensity short “trigger” pulse. The result shows that this method can be used to detect boiling bubbles and the following generated cavitation bubbles at their early stage. By automatically stopping HIFU exposure immediately after detecting the bubbles, overheating was prevented and the deviation of the length of the coagulated region was reduced.

Voltage-based Device Tracking in a 1.5 Tesla MRI during Imaging: Initial validation in swine models

PubMed Central

Schmidt, Ehud J; Tse, Zion TH; Reichlin, Tobias R; Michaud, Gregory F; Watkins, Ronald D; Butts-Pauly, Kim; Kwong, Raymond Y; Stevenson, William; Schweitzer, Jeffrey; Byrd, Israel; Dumoulin, Charles L

2013-01-01

Purpose Voltage-based device-tracking (VDT) systems are commonly used for tracking invasive devices in electrophysiological (EP) cardiac-arrhythmia therapy. During EP procedures, electro-anatomic-mapping (EAM) workstations provide guidance by integrating VDT location and intra-cardiac-ECG information with X-ray, CT, Ultrasound, and MR images. MR assists navigation, mapping and radio-frequency-ablation. Multi-modality interventions require multiple patient transfers between an MRI and the X-ray/ultrasound EP suite, increasing the likelihood of patient-motion and image mis-registration. An MRI-compatible VDT system may increase efficiency, since there is currently no single method to track devices both inside and outside the MRI scanner. Methods An MRI-compatible VDT system was constructed by modifying a commercial system. Hardware was added to reduce MRI gradient-ramp and radio-frequency-unblanking-pulse interference. VDT patches and cables were modified to reduce heating. Five swine cardiac VDT EAM-mapping interventions were performed, navigating inside and thereafter outside the MRI. Results Three-catheter VDT interventions were performed at >12 frames-per-second both inside and outside the MRI scanner with <3mm error. Catheters were followed on VDT- and MRI-derived maps. Simultaneous VDT and imaging was possible in repetition-time (TR) >32 msec sequences with <0.5mm errors, and <5% MRI SNR loss. At shorter TRs, only intra-cardiac-ECG was reliable. RF Heating was <1.5C°. Conclusion An MRI-compatible VDT system is feasible. PMID:23580479

Radio frequency detection assembly and method for detecting radio frequencies

DOEpatents

Cown, Steven H.; Derr, Kurt Warren

2010-03-16

A radio frequency detection assembly is described and which includes a radio frequency detector which detects a radio frequency emission produced by a radio frequency emitter from a given location which is remote relative to the radio frequency detector; a location assembly electrically coupled with the radio frequency detector and which is operable to estimate the location of the radio frequency emitter from the radio frequency emission which has been received; and a radio frequency transmitter electrically coupled with the radio frequency detector and the location assembly, and which transmits a radio frequency signal which reports the presence of the radio frequency emitter.

Preoperative ultrasound still valuable for radio-cephalic arteriovenous fistula creation?

PubMed

Pajek, Jernej; Malovrh, Marko

2017-03-06

Radio-cephalic arteriovenous fistula is a prototype hemodialysis access with small incidences of infection and distal ischemia, it spares proximal veins for future access use and it helps in the maturation of veins that may be used for more proximal access creations. This access type is prone to higher early failure rates compared to more proximal fistulas and there are unsolved uncertainties regarding exact ultrasound parameters predictive of fistula outcome. Evolution of ultrasound use has yielded several functional parameters that can be measured in addition to anatomical lumen sizes, which remain core parameters on which the decision to construct fistula in radio-cephalic forearm position is based. We propose to use arterial hyperemic response and wall morphology to aid in this decision when radial artery diameter falls in the interval with predictive uncertainty of 1.6-1.9 mm and to use venous flow pattern, respiratory variation, radial artery status and possibly venous distensibility when cephalic vein augmented diameter lies in the borderline interval of 2-2.4 mm. Ultrasound preoperative mapping and planning should be followed by expert surgical technique and several technique modifications of the classical end-to-side approach are possible to enhance operation outcome and diminish the incidence of stenosis most often present at juxta-anastomotic location. In our experience radio-cephalic arteriovenous fistula remains the golden standard for hemodialysis access and preoperative ultrasound the single best imaging modality to plan the operation and predict its success.

Effectiveness of advertising availability of prenatal ultrasound on uptake of antenatal care in rural Uganda: A cluster randomized trial

PubMed Central

Anguyo, Geoffrey; Meaney, Christopher; Yuan Kong, Ling; Malhame, Isabelle; Pace, Romina; Sodhi, Sumeet; Silverman, Michael

2017-01-01

In rural Uganda pregnant women often lack access to health services, do not attend antenatal care, and tend to utilize traditional healers/birth attendants. We hypothesized that receiving a message advertising that “you will be able to see your baby by ultrasound” would motivate rural Ugandan women who otherwise might use a traditional birth attendant to attend antenatal care, and that those women would subsequently be more satisfied with care. A cluster randomized trial was conducted across eight rural sub-counties in southwestern Uganda. Sub-counties were randomized to a control arm, with advertisement of antenatal care with no mention of portable obstetric ultrasound (four communities, n = 59), or an intervention arm, with advertisement of portable obstetric ultrasound. Advertisement of portable obstetric ultrasound was further divided into intervention A) word of mouth advertisement of portable obstetric ultrasound and antenatal care (one communitity, n = 16), B) radio advertisement of only antenatal care and word of mouth advertisement of antenatal care and portable obstetric ultrasound (one community, n = 7), or C) word of mouth + radio advertisement of both antenatal care and portable obstetric ultrasound (two communities, n = 75). The primary outcome was attendance to antenatal care. 159 women presented to antenatal care across eight sub-counties. The rate of attendance was 65.1 (per 1000 pregnant women, 95% CI 38.3–110.4) where portable obstetric ultrasound was advertised by radio and word of mouth, as compared to a rate of 11.1 (95% CI 6.1–20.1) in control communities (rate ratio 5.9, 95% CI 2.6–13.0, p<0.0001). Attendance was also improved in women who had previously seen a traditional healer (13.0, 95% CI 5.4–31.2) compared to control (1.5, 95% CI 0.5–5.0, rate ratio 8.7, 95% CI 2.0–38.1, p = 0.004). By advertising antenatal care and portable obstetric ultrasound by radio attendance was significantly improved. This study suggests that women can be motivated to attend antenatal care when offered the concrete incentive of seeing their baby. PMID:28403187

Photoacoustic tomography and sensing in biomedicine

PubMed Central

Li, Changhui; Wang, Lihong V.

2010-01-01

Photoacoustics has been broadly studied in biomedicine, for both human and small animal tissues. Photoacoustics uniquely combines the absorption contrast of light or radio frequency waves with ultrasound resolution. Moreover, it is non-ionizing and non-invasive, and is the fastest growing new biomedical method, with clinical applications on the way. This article provides a brief review of recent developments in photoacoustics in biomedicine, from basic principles to applications. The emphasized areas include the new imaging modalities, hybrid detection methods, photoacoustic contrast agents, and the photoacoustic Doppler effect, as well as translational research topics. PMID:19724102

Effects of Radio Frequency and Ultrasound Cavitation Therapy on Serum C-reactive Protein and Pro-oxidant-Antioxidant Levels.

PubMed

Mohammadzadeh, Mahsa; Nasrfard, Samira; Nezafati, Pouya; Arabpour, Mahla; Ghaane, Narjes; Salehi, Maryam; Safarian, Mohammad; Ghayour-Mobarhan, Majid; Ferns, Gordon A; Norouzy, Abdolreza

2016-05-01

A combination of radio-frequency (RF) and ultrasound cavitation (UC) has been reported to reduce indices of obesity. In this study, we aimed to investigate the effect of a combination of these techniques on anthropometric indices, pro-oxidant-antioxidant balance (PAB), and serum high-sensitivity C-reactive protein (hs-CRP). This randomized clinical trial was performed on 50 healthy women between January 2014 and June 2014 in Ghaem Hospital, Mashhad, Iran. Participants were randomized to one of two groups, both of which received a low-calorie diet containing 500-kcal energy deficit per day. The trial group included twenty-five subjects who were assigned to the combined treatment of RF and ultrasound cavitation program of abdomen and flank areas. There were twenty-five control subjects who received the low calorie diet alone. Biochemical markers, including serum hs-CRP and PAB values, and anthropometric indices were measured in the intervention group and healthy controls. For both the intervention and control groups, waist circumference was reduced significantly by 3.76 ± 1.69 and 2.40 ± 1.04, respectively (P < 0.05). In addition, abdominal circumference was reduced by 9.5 ± 2.66 and 3.12 ± 1.88, in these groups, respectively (P < 0.001). Decrement of PAB level in the intervention group, and its increment in the control group, were not significant (P > 0.05). In addition, reductions of hs-CRP and PAB between the two studied groups during five weeks of study were not significant (P > 0.05). Although there were significant reductions in anthropometric indices following treatment with RF and UC, the effects on serum PAB or hs-CRP were no significantly different, compared to the control group. Further studies are needed to confirm the beneficial effect for the use of these techniques.

Using redundancy of round-trip ultrasound signal for non-continuous arrays: Application to gap and blockage compensation.

PubMed

Robert, Jean-Luc; Erkamp, Ramon; Korukonda, Sanghamithra; Vignon, François; Radulescu, Emil

2015-11-01

In ultrasound imaging, an array of elements is used to image a medium. If part of the array is blocked by an obstacle, or if the array is made from several sub-arrays separated by a gap, grating lobes appear and the image is degraded. The grating lobes are caused by missing spatial frequencies, corresponding to the blocked or non-existing elements. However, in an active imaging system, where elements are used both for transmitting and receiving, the round trip signal is redundant: different pairs of transmit and receive elements carry similar information. It is shown here that, if the gaps are smaller than the active sub-apertures, this redundancy can be used to compensate for the missing signals and recover full resolution. Three algorithms are proposed: one is based on a synthetic aperture method, a second one uses dual-apodization beamforming, and the third one is a radio frequency (RF) data based deconvolution. The algorithms are evaluated on simulated and experimental data sets. An application could be imaging through ribs with a large aperture.

Non-invasive subcutaneous fat reduction: a review.

PubMed

Kennedy, J; Verne, S; Griffith, R; Falto-Aizpurua, L; Nouri, K

2015-09-01

The risks, financial costs and lengthy downtime associated with surgical procedures for fat reduction have led to the development of a number of non-invasive techniques. Non-invasive body contouring now represents the fastest growing area of aesthetic medicine. There are currently four leading non-invasive techniques for reducing localized subcutaneous adipose tissue: low-level laser therapy (LLLT), cryolipolysis, radio frequency (RF) and high-intensity focused ultrasound (HIFU). To review and compare leading techniques and clinical outcomes of non-invasive subcutaneous fat reduction. The terms 'non-invasive', 'low-level laser', 'cryolipolysis', 'ultrasound' and 'radio frequency' were combined with 'lipolysis', 'fat reduction' or 'body contour' during separate searches in the PubMed database. We identified 31 studies (27 prospective clinical studies and four retrospective chart reviews) with a total of 2937 patients that had been treated with LLLT (n = 1114), cryolipolysis (n = 706), HIFU (n = 843) or RF (n = 116) or other techniques (n = 158) for fat reduction or body contouring. A majority of these patients experienced significant and satisfying results without any serious adverse effects. The studies investigating these devices have all varied in treatment regimen, body locations, follow-up times or outcome operationalization. Each technique differs in offered advantages and severity of adverse effects. However, multiple non-invasive devices are safe and effective for circumferential reduction in local fat tissue by 2 cm or more across the abdomen, hips and thighs. Results are consistent and reproducible for each device and none are associated with any serious or permanent adverse effects. © 2015 European Academy of Dermatology and Venereology.

High-Resolution Ultrasonic Imaging of Dento-Periodontal Tissues Using a Multi-Element Phased Array System.

PubMed

Nguyen, Kim-Cuong T; Le, Lawrence H; Kaipatur, Neelambar R; Zheng, Rui; Lou, Edmond H; Major, Paul W

2016-10-01

Intraoral ultrasonography uses high-frequency mechanical waves to study dento-periodontium. Besides the advantages of portability and cost-effectiveness, ultrasound technique has no ionizing radiation. Previous studies employed a single transducer or an array of transducer elements, and focused on enamel thickness and distance measurement. This study used a phased array system with a 128-element array transducer to image dento-periodontal tissues. We studied two porcine lower incisors from a 6-month-old piglet using 20-MHz ultrasound. The high-resolution ultrasonographs clearly showed the cross-sectional morphological images of the hard and soft tissues. The investigation used an integration of waveform analysis, travel-time calculation, and wavefield simulation to reveal the nature of the ultrasound data, which makes the study novel. With the assistance of time-distance radio-frequency records, we robustly justified the enamel-dentin interface, dentin-pulp interface, and the cemento-enamel junction. The alveolar crest level, the location of cemento-enamel junction, and the thickness of alveolar crest were measured from the images and compared favorably with those from the cone beam computed tomography with less than 10% difference. This preliminary and fundamental study has reinforced the conclusions from previous studies, that ultrasonography has great potential to become a non-invasive diagnostic imaging tool for quantitative assessment of periodontal structures and better delivery of oral care.

Detection of tissue coagulation by decorrelation of ultrasonic echo signals in cavitation-enhanced high-intensity focused ultrasound treatment.

PubMed

Yoshizawa, Shin; Matsuura, Keiko; Takagi, Ryo; Yamamoto, Mariko; Umemura, Shin-Ichiro

2016-01-01

A noninvasive technique to monitor thermal lesion formation is necessary to ensure the accuracy and safety of high-intensity focused ultrasound (HIFU) treatment. The purpose of this study is to ultrasonically detect the tissue change due to thermal coagulation in the HIFU treatment enhanced by cavitation microbubbles. An ultrasound imaging probe transmitted plane waves at a center frequency of 4.5 MHz. Ultrasonic radio-frequency (RF) echo signals during HIFU exposure at a frequency of 1.2 MHz were acquired. Cross-correlation coefficients were calculated between in-phase and quadrature (IQ) data of two B-mode images with an interval time of 50 and 500 ms for the estimation of the region of cavitation and coagulation, respectively. Pathological examination of the coagulated tissue was also performed to compare with the corresponding ultrasonically detected coagulation region. The distribution of minimum hold cross-correlation coefficient between two sets of IQ data with 50-ms intervals was compared with a pulse inversion (PI) image. The regions with low cross-correlation coefficients approximately corresponded to those with high brightness in the PI image. The regions with low cross-correlation coefficients in 500-ms intervals showed a good agreement with those with significant change in histology. The results show that the regions of coagulation and cavitation could be ultrasonically detected as those with low cross-correlation coefficients between RF frames with certain intervals. This method will contribute to improve the safety and accuracy of the HIFU treatment enhanced by cavitation microbubbles.

Low-frequency ultrasound induces oxygen vacancies formation and visible light absorption in TiO2 P-25 nanoparticles.

PubMed

Osorio-Vargas, Paula A; Pulgarin, Cesar; Sienkiewicz, Andrzej; Pizzio, Luis R; Blanco, Mirta N; Torres-Palma, Ricardo A; Pétrier, Christian; Rengifo-Herrera, Julián A

2012-05-01

Low-frequency ultrasound (LFUS) irradiation induces morphological, optical and surface changes in the commercial nano-TiO(2)-based photocatalyst, Evonik-Degussa P-25. Low-temperature electron spin resonance (ESR) measurements performed on this material provided the first experimental evidence for the formation of oxygen vacancies (V(o)), which were also found responsible for the visible-light absorption. The V(o) surface defects might result from high-speed inter-particle collisions and shock waves generated by LFUS sonication impacting the TiO(2) particles. This is in contrast to a number of well-established technologies, where the formation of oxygen vacancies on the TiO(2) surface often requires harsh technological conditions and complicated procedures, such as annealing at high temperatures, radio-frequency-induced plasma or ion sputtering. Thus, this study reports for the first time the preparation of visible-light responsive TiO(2)-based photocatalysts by using a simple LFUS-based approach to induce oxygen vacancies at the nano-TiO(2) surface. These findings might open new avenues for synthesis of novel nano-TiO(2)-based photocatalysts capable of destroying water or airborne pollutants and microorganisms under visible light illumination. Copyright © 2011 Elsevier B.V. All rights reserved.

3D ultrasound Nakagami imaging for radiation-induced vaginal fibrosis

NASA Astrophysics Data System (ADS)

Yang, Xiaofeng; Rossi, Peter; Shelton, Joseph; Bruner, Debrorah; Tridandapani, Srini; Liu, Tian

2014-03-01

Radiation-induced vaginal fibrosis is a debilitating side-effect affecting up to 80% of women receiving radiotherapy for their gynecological (GYN) malignancies. Despite the significant incidence and severity, little research has been conducted to identify the pathophysiologic changes of vaginal toxicity. In a previous study, we have demonstrated that ultrasound Nakagami shape and PDF parameters can be used to quantify radiation-induced vaginal toxicity. These Nakagami parameters are derived from the statistics of ultrasound backscattered signals to capture the physical properties (e.g., arrangement and distribution) of the biological tissues. In this paper, we propose to expand this Nakagami imaging concept from 2D to 3D to fully characterize radiation-induced changes to the vaginal wall within the radiation treatment field. A pilot study with 5 post-radiotherapy GYN patients was conducted using a clinical ultrasound scanner (6 MHz) with a mechanical stepper. A serial of 2D ultrasound images, with radio-frequency (RF) signals, were acquired at 1 mm step size. The 2D Nakagami shape and PDF parameters were calculated from the RF signal envelope with a sliding window, and then 3D Nakagami parameter images were generated from the parallel 2D images. This imaging method may be useful as we try to monitor radiation-induced vaginal injury, and address vaginal toxicities and sexual dysfunction in women after radiotherapy for GYN malignancies.

Hyperthermia for treating cancer

MedlinePlus

... forms of energy may be used, including: Radio waves Microwaves Ultrasound waves Heat may be delivered using: An external machine ... rectum. A needle-like probe to sends radio wave energy directly into the tumor to kill cancer ...

Pulse based sensor networking using mechanical waves through metal substrates

NASA Astrophysics Data System (ADS)

Lorenz, S.; Dong, B.; Huo, Q.; Tomlinson, W. J.; Biswas, S.

2013-05-01

This paper presents a novel wireless sensor networking technique using ultrasonic signal as the carrier wave for binary data exchange. Using the properties of lamb wave propagation through metal substrates, the proposed network structure can be used for runtime transport of structural fault information to ultrasound access points. Primary applications of the proposed sensor networking technique will include conveying fault information on an aircraft wing or on a bridge to an ultrasonic access point using ultrasonic wave through the structure itself (i.e. wing or bridge). Once a fault event has been detected, a mechanical pulse is forwarded to the access node using shortest path multi-hop ultrasonic pulse routing. The advantages of mechanical waves over traditional radio transmission using pulses are the following: First, unlike radio frequency, surface acoustic waves are not detectable outside the medium, which increases the inherent security for sensitive environments in respect to tapping. Second, event detection can be represented by the injection of a single mechanical pulse at a specific temporal position, whereas radio messages usually take several bits. The contributions of this paper are: 1) Development of a transceiver for transmitting/receiving ultrasound pulses with a pulse loss rate below 2·10-5 and false positive rate with an upper bound of 2·10-4. 2) A novel one-hop distance estimation based on the properties of lamb wave propagation with an accuracy of above 80%. 3) Implementation of a wireless sensor network using mechanical wave propagation for event detection on a 2024 aluminum alloy commonly used for aircraft skin construction.

Radio frequency ablation of small renal tumors:: intermediate results.

PubMed

Hwang, J J; Walther, M M; Pautler, S E; Coleman, J A; Hvizda, J; Peterson, James; Linehan, W M; Wood, B J

2004-05-01

With evolving radio frequency technology, the clinical application of radio frequency ablation (RFA) has been actively investigated in the treatment for small renal tumors. We present our intermediate patient outcomes after RFA. Since January 2001, 17 patients with a total of 24 hereditary renal tumors ranging from 1.2 to 2.85 cm were treated with RFA using the 200 W Cool-tip RF System (Radionics, Burlington, Massachusetts) under laparoscopic (9) or percutaneous (8) guidance and had a minimum 1-year followup. A percutaneous approach was considered unsuitable if kidney tumors were contiguous to bowel, ureter or large vessels. Treatment eligibility criteria included an average tumor diameter of less than 3.0 cm, tumor growth during 1 year and solid appearance with contrast enhancement (HU change greater than 20) on computerized tomography (CT). Postoperative followup consisted of CT with and without intravenous contrast, and renal function assessment at regular intervals. Median patient age was 38 years (range 20 to 51). At a median followup of 385 days (range 342 to 691), median tumor or thermal lesion diameter decreased from 2.26 to 1.62 cm (p = 0.0013), and only 1 lesion (4%), which was located centrally near the hilum, exhibited contrast enhancement (HU change greater than 10) on CT at 12 months. Of the 15 renal tumors ablated laparoscopically, 13 were in direct contact with the bowel and 2 were abutting the ureter, necessitating mobilization before RFA. Laparoscopic ultrasound was used to guide radio frequency electrode placement and monitor the ablation process in these cases. Operative time and intraoperative blood loss (mean +/- standard mean of error) were 243 +/- 29 minutes and 67 +/- 9 cc, respectively. In 1 patient whose ureter was adherent to the tumor a ureteropelvic junction obstruction developed after laparoscopic RFA, requiring open repair. At the minimum 1-year followup 23 of 24 ablated tumors lacked contrast uptake on CT, meeting our radiographic criteria of successful RFA treatment. RFA treatment of small renal tumors using the Radionics system appears to result in superior treatment outcomes compared to those of earlier series with lower radio frequency power generators. A high wattage generator might attain more consistent energy deposition with subsequent cell death in the targeted tissue due to less convective heat loss.

Displacement analysis of diagnostic ultrasound backscatter: A methodology for characterizing, modeling, and monitoring high intensity focused ultrasound therapy

PubMed Central

Speyer, Gavriel; Kaczkowski, Peter J.; Brayman, Andrew A.; Crum, Lawrence A.

2010-01-01

Accurate monitoring of high intensity focused ultrasound (HIFU) therapy is critical for widespread clinical use. Pulse-echo diagnostic ultrasound (DU) is known to exhibit temperature sensitivity through relative changes in time-of-flight between two sets of radio frequency (RF) backscatter measurements, one acquired before and one after therapy. These relative displacements, combined with knowledge of the exposure protocol, material properties, heat transfer, and measurement noise statistics, provide a natural framework for estimating the administered heating, and thereby therapy. The proposed method, termed displacement analysis, identifies the relative displacements using linearly independent displacement patterns, or modes, each induced by a particular time-varying heating applied during the exposure interval. These heating modes are themselves linearly independent. This relationship implies that a linear combination of displacement modes aligning the DU measurements is the response to an identical linear combination of heating modes, providing the heating estimate. Furthermore, the accuracy of coefficient estimates in this approximation is determined a priori, characterizing heating, thermal dose, and temperature estimates for any given protocol. Predicted performance is validated using simulations and experiments in alginate gel phantoms. Evidence for a spatially distributed interaction between temperature and time-of-flight changes is presented. PMID:20649206

Multi-dynamic range compressional wave detection using optical-frequency comb

NASA Astrophysics Data System (ADS)

Minamikawa, Takeo; Masuoka, Takashi; Oe, Ryo; Nakajima, Yoshiaki; Yamaoka, Yoshihisa; Minoshima, Kaoru; Yasui, Takeshi

2018-02-01

Compressional wave detection is useful means for health monitoring of building, detection of abnormal vibration of moving objects, defect evaluation, and biomedical imaging such as echography and photoacoustic imaging. The frequency of the compressional wave is varied from quasi-static to a few tens of megahertz depending on applications. Since the dynamic range of general compressional wave detectors is limited, we need to choose a proper compressional wave detector depending on applications. For the compressional wave detection with wide dynamic range, two or more detectors with different detection ranges is required. However, these detectors with different detection ranges generally has different accuracy and precision, disabling the seamless detection over these detection ranges. In this study, we proposed a compressional wave detector employing optical frequency comb (OFC). The compressional wave was sensed with a part of an OFC cavity, being encoded into OFC. The spectrally encoded OFC was converted to radio-frequency by the frequency link nature of OFC. The compressional wave-encoded radio-frequency can therefore be directly measured with a high-speed photodetector. To enhance the dynamic range of the compressional wave detection, we developed a cavityfeedback-based system and a phase-sensitive detection system, both of which the accuracy and precision are coherently linked to these of the OFC. We provided a proof-of-principle demonstration of the detection of compressional wave from quasi-static to ultrasound wave by using the OFC-based compressional wave sensor. Our proposed approach will serve as a unique and powerful tool for detecting compressional wave versatile applications in the future.

Combined passive detection and ultrafast active imaging of cavitation events induced by short pulses of high-intensity ultrasound.

PubMed

Gateau, Jérôme; Aubry, Jean-François; Pernot, Mathieu; Fink, Mathias; Tanter, Mickaël

2011-03-01

The activation of natural gas nuclei to induce larger bubbles is possible using short ultrasonic excitations of high amplitude, and is required for ultrasound cavitation therapies. However, little is known about the distribution of nuclei in tissues. Therefore, the acoustic pressure level necessary to generate bubbles in a targeted zone and their exact location are currently difficult to predict. To monitor the initiation of cavitation activity, a novel all-ultrasound technique sensitive to single nucleation events is presented here. It is based on combined passive detection and ultrafast active imaging over a large volume using the same multi-element probe. Bubble nucleation was induced using a focused transducer (660 kHz, f-number = 1) driven by a high-power electric burst (up to 300 W) of one to two cycles. Detection was performed with a linear array (4 to 7 MHz) aligned with the single-element focal point. In vitro experiments in gelatin gel and muscular tissue are presented. The synchronized passive detection enabled radio-frequency data to be recorded, comprising high-frequency coherent wave fronts as signatures of the acoustic emissions linked to the activation of the nuclei. Active change detection images were obtained by subtracting echoes collected in the unnucleated medium. These indicated the appearance of stable cavitating regions. Because of the ultrafast frame rate, active detection occurred as quickly as 330 μs after the high-amplitude excitation and the dynamics of the induced regions were studied individually.

Combined passive detection and ultrafast active imaging of cavitation events induced by short pulses of high-intensity ultrasound

PubMed Central

Gateau, Jérôme; Aubry, Jean-François; Pernot, Mathieu; Fink, Mathias; Tanter, Mickaël

2011-01-01

The activation of natural gas nuclei to induce larger bubbles is possible using short ultrasonic excitations of high amplitude, and is required for ultrasound cavitation therapies. However, little is known about the distribution of nuclei in tissues. Therefore, the acoustic pressure level necessary to generate bubbles in a targeted zone and their exact location are currently difficult to predict. In order to monitor the initiation of cavitation activity, a novel all-ultrasound technique sensitive to single nucleation events is presented here. It is based on combined passive detection and ultrafast active imaging over a large volume and with the same multi-element probe. Bubble nucleation was induced with a focused transducer (660kHz, f#=1) driven by a high power (up to 300 W) electric burst of one to two cycles. Detection was performed with a linear array (4–7MHz) aligned with the single-element focal point. In vitro experiments in gelatin gel and muscular tissue are presented. The synchronized passive detection enabled radio-frequency data to be recorded, comprising high-frequency coherent wave fronts as signatures of the acoustic emissions linked to the activation of the nuclei. Active change detection images were obtained by subtracting echoes collected in the unucleated medium. These indicated the appearance of stable cavitating regions. Thanks to the ultrafast frame rate, active detection occurred as soon as 330 μs after the high amplitude excitation and the dynamics of the induced regions were studied individually. PMID:21429844

Radio frequency power load and associated method

NASA Technical Reports Server (NTRS)

Sims, III, William Herbert (Inventor); Chavers, Donald Gregory (Inventor); Richeson, James J. (Inventor)

2010-01-01

A radio frequency power load and associated method. A radio frequency power load apparatus includes a container and a fluid having an ion source therein, the fluid being contained in the container. Two conductors are immersed in the fluid. A radio frequency transmission system includes a radio frequency transmitter, a radio frequency amplifier connected to the transmitter and a radio frequency power load apparatus connected to the amplifier. The apparatus includes a fluid having an ion source therein, and two conductors immersed in the fluid. A method of dissipating power generated by a radio frequency transmission system includes the steps of: immersing two conductors of a radio frequency power load apparatus in a fluid having an ion source therein; and connecting the apparatus to an amplifier of the transmission system.

Linear enhancement after radio-frequency ablation for hepatocellular carcinoma: is it a sign of recurrence?

PubMed

Takahashi, Masanori; Maruyama, Hitoshi; Shimada, Taro; Kamezaki, Hidehiro; Okabe, Shinichiro; Kanai, Fumihiko; Yoshikawa, Masaharu; Yokosuka, Osamu

2012-11-01

This prospective study was performed in 179 hepatocellular carcinoma (HCC) lesions treated by radio-frequency ablation (RFA) to explore the clinical outcome of "linear enhancement" on contrast-enhanced sonogram. Thirty-three lesions (18.4%) showed linear enhancement, a linear-shaped positive enhancement in the RFA-treated area. Seventeen of them were followed up with no treatment (remaining 16; dropout in eight, additional RFA in six and ineffective treatment in two) and three lesions (3/17, 17.6%) showed local tumor progression corresponding to linear enhancement at 7, 14, 19 months after RFA. Although there was no significant difference in local recurrence rate between the lesions with (3/17) and without linear enhancement (10/35), local tumor progression inside the ablation zone occurred only in the lesions with linear enhancement. In conclusion, linear enhancement inside the RFA-treated area should be followed up within 7 months because it has a risk of local tumor progression. Histology of linear enhancement and its influence on distant recurrence remain to be solved. Copyright © 2012 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

14 CFR 417.417 - Propellants and explosives.

Code of Federal Regulations, 2012 CFR

2012-01-01

... radio frequency radiation sources in a radio frequency radiation exclusion area. A launch operator must determine the vulnerability of its electro-explosive devices and systems to radio frequency radiation and establish radio frequency radiation power limits or radio frequency radiation exclusion areas as required by...

14 CFR 417.417 - Propellants and explosives.

Code of Federal Regulations, 2013 CFR

2013-01-01

... radio frequency radiation sources in a radio frequency radiation exclusion area. A launch operator must determine the vulnerability of its electro-explosive devices and systems to radio frequency radiation and establish radio frequency radiation power limits or radio frequency radiation exclusion areas as required by...

14 CFR 417.417 - Propellants and explosives.

Code of Federal Regulations, 2011 CFR

2011-01-01

... radio frequency radiation sources in a radio frequency radiation exclusion area. A launch operator must determine the vulnerability of its electro-explosive devices and systems to radio frequency radiation and establish radio frequency radiation power limits or radio frequency radiation exclusion areas as required by...

14 CFR 417.417 - Propellants and explosives.

Code of Federal Regulations, 2014 CFR

2014-01-01

... radio frequency radiation sources in a radio frequency radiation exclusion area. A launch operator must determine the vulnerability of its electro-explosive devices and systems to radio frequency radiation and establish radio frequency radiation power limits or radio frequency radiation exclusion areas as required by...

Ultrasound elastomicroscopy for articular cartilage: from static to transient and 1D to 2D

NASA Astrophysics Data System (ADS)

Zheng, Yongping; Bridal, Sharon L.; Shi, Jun; Saied, Amena; Lu, Minghua; Jaffre, Britta; Mak, Arthur F. T.; Laugier, Pascal; Qin, Ling

2003-05-01

Articular cartilage (AC) is a biological weight-bearing tissue covering the ends of articulating bones within synovial joints. Its function very much depends on the unique multi-layered structure and the depth-dependent material properties, which have not been well invetigated nondestructively. In this study, transient depth-dependent material properties of bovine patella cartilage were measured using ultrasound elastomicroscopy methods. A 50 MHz focused ultrasound transducer was used to collect A-mode ultrasound echoes from the articular cartilage during the compression and subsequent force-relaxation. The transient displacements of the cartilage tissues at different depths were calculated from the ultrasound echoes using a cross-correlation technique. It was observed that the strains in the superficial zone were much larger than those in the middle and deep zones as the equilibrium state was approached. The tissues inside the AC layer continued to move during the force-relaxation phase after the compression was completed. This process has been predicted by a biphasic theory. In this study, it has been verified experimentally. It was also observed that the tissue deformations at different depths of AC were much more evenly distributed before force-relaxation. AC specimens were also investigated using a 2D ultrasound elastomicroscopy system that included a 3D translating system for moving the ultrasound transducer over the specimens. B-mode RF ultrasound signals were collected from the specimens under different loading levels applied with a specially designed compressor. Preliminary results demonstrated that the scanning was repeatable with high correlation of radio frequency signals obtained from the same site during different scans when compression level was unchanged (R2 > 0.97). Strains of the AC specimens were mapped using data collected with this ultrasound elastomicroscope. This system can also be potentially used for the assessment of other biological tissues, bioengineered tissues or biomaterials with fine structures.

Combinational light emitting diode-high frequency focused ultrasound treatment for HeLa cell.

PubMed

Choe, Se-Woon; Park, Kitae; Park, Chulwoo; Ryu, Jaemyung; Choi, Hojong

2017-12-01

Light sources such as laser and light emitting diode or ultrasound devices have been widely used for cancer therapy and regenerative medicines, since they are more cost-effective and less harmful than radiation therapy, chemotherapy or magnetic treatment. Compared to laser and low intensity ultrasound techniques, light emitting diode and high frequency focused ultrasound shows enhanced therapeutic effects, especially for small tumors. We propose combinational light emitting diode-high frequency focused ultrasound treatment for human cervical cancer HeLa cells. Individual red, green, and blue light emitting diode light only, high frequency focused ultrasound only, or light emitting diode light combined with high frequency focused ultrasound treatments were applied in order to characterize the responses of HeLa cells. Cell density exposed by blue light emitting diode light combined with high frequency focused ultrasound (2.19 ± 0.58%) was much lower than that of cells exposed by red and green light emitting diode lights (81.71 ± 9.92% and 61.81 ± 4.09%), blue light emitting diode light (11.19 ± 2.51%) or high frequency focused ultrasound only (9.72 ± 1.04%). We believe that the proposed combinational blue light emitting diode-high frequency focused ultrasound treatment could have therapeutic benefits to alleviate cancer cell proliferation.

Frequency Dependence of Ultrasound Neurostimulation in the Mouse Brain

PubMed Central

Ye, Patrick Peiyong; Brown, Julian R.; Pauly, Kim Butts

2016-01-01

Ultrasound neuromodulation holds promise as a non-invasive technique for neuromodulation of the central nervous system. However, much remains to be determined about how the technique can be transformed into a useful technology, including the effect of ultrasound frequency. Previous studies have demonstrated neuromodulation in vivo using frequencies less than 1 MHz, with a trend towards improved efficacy with lower frequency. However, using higher frequencies could offer improved ultrasound spatial resolution. We investigate the ultrasound neuromodulation effects in mice at various frequencies both below and above 1 MHz and find that frequencies up to 2.9 MHz can still be effective for generating motor responses, but also confirm that as frequency increases, sonications require significantly more intensity to achieve equivalent efficacy. We argue that our results provide evidence that favors either a particle displacement or a cavitation-based mechanism for the phenomenon of ultrasound neuromodulation. PMID:27090861

Three-dimensional sheaf of ultrasound planes reconstruction (SOUPR) of ablated volumes.

PubMed

Ingle, Atul; Varghese, Tomy

2014-08-01

This paper presents an algorithm for 3-D reconstruction of tumor ablations using ultrasound shear wave imaging with electrode vibration elastography. Radio-frequency ultrasound data frames are acquired over imaging planes that form a subset of a sheaf of planes sharing a common axis of intersection. Shear wave velocity is estimated separately on each imaging plane using a piecewise linear function fitting technique with a fast optimization routine. An interpolation algorithm then computes velocity maps on a fine grid over a set of C-planes that are perpendicular to the axis of the sheaf. A full 3-D rendering of the ablation can then be created from this stack of C-planes; hence the name "Sheaf Of Ultrasound Planes Reconstruction" or SOUPR. The algorithm is evaluated through numerical simulations and also using data acquired from a tissue mimicking phantom. Reconstruction quality is gauged using contrast and contrast-to-noise ratio measurements and changes in quality from using increasing number of planes in the sheaf are quantified. The highest contrast of 5 dB is seen between the stiffest and softest regions of the phantom. Under certain idealizing assumptions on the true shape of the ablation, good reconstruction quality while maintaining fast processing rate can be obtained with as few as six imaging planes suggesting that the method is suited for parsimonious data acquisitions with very few sparsely chosen imaging planes.

Unpowered wireless generation and sensing of ultrasound

NASA Astrophysics Data System (ADS)

Huang, Haiying

2013-04-01

This paper presents a wireless ultrasound pitch-catch system that demonstrates the wireless generation and sensing of ultrasounds based on the principle of frequency conversion. The wireless ultrasound pitch-catch system consists of a wireless interrogator and two wireless ultrasound transducers. The wireless interrogator generates an ultrasound-modulated signal and a carrier signal, both at the microwave frequency, and transmits these two signals to the wireless ultrasound actuator using a pair of antennas. Upon receiving these two signals, the wireless ultrasound actuator recovers the ultrasound excitation signal using a passive mixer and then supplies it to a piezoelectric wafer sensor for ultrasound generation in the structure. For wireless ultrasound sensing, the frequency conversion process is reversed. The ultrasound sensing signal is up-converted to a microwave signal by the wireless ultrasound sensor and is recovered at the wireless interrogator using a homodyne receiver. To differentiate the wireless actuator from the wireless sensor, each wireless transducer is equipped with a narrowband microwave filter so that it only responds to the carrier frequency that matches the filter's operation bandwidth. The principle of operation of the wireless pitch-catch system, the hardware implementation, and the associated data processing algorithm to recover the ultrasound signal from the wirelessly received signal are described. The wirelessly acquired ultrasound signal is compared with those acquired using wired connection in both time and frequency domain.

Development of a real-time, high-frequency ultrasound digital beamformer for high-frequency linear array transducers.

PubMed

Hu, Chang-Hong; Xu, Xiao-Chen; Cannata, Jonathan M; Yen, Jesse T; Shung, K Kirk

2006-02-01

A real-time digital beamformer for high-frequency (>20 MHz) linear ultrasonic arrays has been developed. The system can handle up to 64-element linear array transducers and excite 16 channels and receive simultaneously at 100 MHz sampling frequency with 8-bit precision. Radio frequency (RF) signals are digitized, delayed, and summed through a real-time digital beamformer, which is implemented using a field programmable gate array (FPGA). Using fractional delay filters, fine delays as small as 2 ns can be implemented. A frame rate of 30 frames per second is achieved. Wire phantom (20 microm tungsten) images were obtained and -6 dB axial and lateral widths were measured. The results showed that, using a 30 MHz, 48-element array with a pitch of 100 microm produced a -6 dB width of 68 microm in the axial and 370 microm in the lateral direction at 6.4 mm range. Images from an excised rabbit eye sample also were acquired, and fine anatomical structures, such as the cornea and lens, were resolved.

Split-mode ultrasonic transducer.

PubMed

Ostrovskii, Igor; Cremaldi, Lucien

2013-08-01

A split-mode ultrasonic transducer is investigated in both theory and experiment. This transducer is a two-dimensional structure of periodically poled domains in a ferroelectric wafer with free surfaces. The acoustic vibrations are excited by a radio frequency electric current applied along the length of the wafer, which allows the basal-plane surfaces to be free of metal coatings and thus ready for further biomedical applications. A specific physical property of this transducer consists of the multiple acousto-electric resonances, which occur due to an acoustic mode split when the acoustic half-wavelength is equal to the domain length. Possible applications include ultrasonic generation and detection at the micro-scale, intravascular sonification and visualization, ultrasound therapy of localized small areas such as the eye, biomedical applications for cell cultures, and traditional nondestructive testing including bones and tissues. A potential use of a non-metallized wafer is a therapeutic application with double action that is both ultrasound itself and an electric field over the wafer. The experimental measurements and theoretical calculations are in good agreement.

Radio Frequency Power Load and Associated Method

NASA Technical Reports Server (NTRS)

Srinivasan, V. Karthik (Inventor); Freestone, Todd M. (Inventor); Sims, William Herbert, III (Inventor)

2014-01-01

A radio frequency power load and associated method. A radio frequency power load apparatus may include a container with an ionized fluid therein. The apparatus may include one conductor immersed in a fluid and another conductor electrically connected to the container. A radio frequency transmission system may include a radio frequency transmitter, a radio frequency amplifier connected to the transmitter and a radio frequency power load apparatus connected to the amplifier. The apparatus may include a fluid having an ion source therein, one conductor immersed in a fluid, and another conductor electrically connected to the container. A method of dissipating power generated by a radio frequency transmission system may include constructing a waveguide with ionized fluid in a container and connecting the waveguide to an amplifier of the transmission system.

Improved Wireless Security through Physical Layer Protocol Manipulation and Radio Frequency Fingerprinting

DTIC Science & Technology

2014-09-18

radios in a cognitive radio network using a radio frequency fingerprinting based method. In IEEE International Conference on Communications (ICC...IMPROVEDWIRELESS SECURITY THROUGH PHYSICAL LAYER PROTOCOL MANIPULATION AND RADIO FREQUENCY FINGERPRINTING DISSERTATION Benjamin W. Ramsey, Captain...PHYSICAL LAYER PROTOCOL MANIPULATION AND RADIO FREQUENCY FINGERPRINTING DISSERTATION Presented to the Faculty Graduate School of Engineering and

Numerical investigation of the inertial cavitation threshold under multi-frequency ultrasound.

PubMed

Suo, Dingjie; Govind, Bala; Zhang, Shengqi; Jing, Yun

2018-03-01

Through the introduction of multi-frequency sonication in High Intensity Focused Ultrasound (HIFU), enhancement of efficiency has been noted in several applications including thrombolysis, tissue ablation, sonochemistry, and sonoluminescence. One key experimental observation is that multi-frequency ultrasound can help lower the inertial cavitation threshold, thereby improving the power efficiency. However, this has not been well corroborated by the theory. In this paper, a numerical investigation on the inertial cavitation threshold of microbubbles (MBs) under multi-frequency ultrasound irradiation is conducted. The relationships between the cavitation threshold and MB size at various frequencies and in different media are investigated. The results of single-, dual and triple frequency sonication show reduced inertial cavitation thresholds by introducing additional frequencies which is consistent with previous experimental work. In addition, no significant difference is observed between dual frequency sonication with various frequency differences. This study, not only reaffirms the benefit of using multi-frequency ultrasound for various applications, but also provides a possible route for optimizing ultrasound excitations for initiating inertial cavitation. Copyright © 2017 Elsevier B.V. All rights reserved.

Harmonic motion imaging for focused ultrasound (HMIFU): a fully integrated technique for sonication and monitoring of thermal ablation in tissues.

PubMed

Maleke, C; Konofagou, E E

2008-03-21

FUS (focused ultrasound), or HIFU (high-intensity-focused ultrasound) therapy, a minimally or non-invasive procedure that uses ultrasound to generate thermal necrosis, has been proven successful in several clinical applications. This paper discusses a method for monitoring thermal treatment at different sonication durations (10 s, 20 s and 30 s) using the amplitude-modulated (AM) harmonic motion imaging for focused ultrasound (HMIFU) technique in bovine liver samples in vitro. The feasibility of HMI for characterizing mechanical tissue properties has previously been demonstrated. Here, a confocal transducer, combining a 4.68 MHz therapy (FUS) and a 7.5 MHz diagnostic (pulse-echo) transducer, was used. The therapy transducer was driven by a low-frequency AM continuous signal at 25 Hz, producing a stable harmonic radiation force oscillating at the modulation frequency. A pulser/receiver was used to drive the pulse-echo transducer at a pulse repetition frequency (PRF) of 5.4 kHz. Radio-frequency (RF) signals were acquired using a standard pulse-echo technique. The temperature near the ablation region was simultaneously monitored. Both RF signals and temperature measurements were obtained before, during and after sonication. The resulting axial tissue displacement was estimated using one-dimensional cross correlation. When temperature at the focal zone was above 48 degrees C during heating, the coagulation necrosis occurred and tissue damage was irreversible. The HMI displacement profiles in relation to the temperature and sonication durations were analyzed. At the beginning of heating, the temperature at the focus increased sharply, while the tissue stiffness decreased resulting in higher HMI displacements. This was confirmed by an increase of 0.8 microm degrees C(-1)(r=0.93, p<.005). After sustained heating, the tissue became irreversibly stiffer, followed by an associated decrease in the HMI displacement (-0.79 microm degrees C(-1), r=-0.92, p<0.001). Repeated experiments showed a reproducible pattern of the HMI displacement changes with a temperature at a slope equal to 0.8+/-0.11 and -0.79+/-0.14 microm degrees C(-1), prior to and after lesion formation in seven bovine liver samples, respectively. This technique was thus capable of following the protein-denatured lesion formation based on the variation of the HMI displacements. This method could, therefore, be applied for real-time monitoring of temperature-related stiffness changes of tissues during FUS, HIFU or other thermal therapies.

Frequency and number of ultrasound lung rockets (B-lines) using a regionally based lung ultrasound examination named vet BLUE (veterinary bedside lung ultrasound exam) in dogs with radiographically normal lung findings.

PubMed

Lisciandro, Gregory R; Fosgate, Geoffrey T; Fulton, Robert M

2014-01-01

Lung ultrasound is superior to lung auscultation and supine chest radiography for many respiratory conditions in human patients. Ultrasound diagnoses are based on easily learned patterns of sonographic findings and artifacts in standardized images. By applying the wet lung (ultrasound lung rockets or B-lines, representing interstitial edema) versus dry lung (A-lines with a glide sign) concept many respiratory conditions can be diagnosed or excluded. The ultrasound probe can be used as a visual stethoscope for the evaluation of human lungs because dry artifacts (A-lines with a glide sign) predominate over wet artifacts (ultrasound lung rockets or B-lines). However, the frequency and number of wet lung ultrasound artifacts in dogs with radiographically normal lungs is unknown. Thus, the primary objective was to determine the baseline frequency and number of ultrasound lung rockets in dogs without clinical signs of respiratory disease and with radiographically normal lung findings using an 8-view novel regionally based lung ultrasound examination called Vet BLUE. Frequency of ultrasound lung rockets were statistically compared based on signalment, body condition score, investigator, and reasons for radiography. Ten left-sided heart failure dogs were similarly enrolled. Overall frequency of ultrasound lung rockets was 11% (95% confidence interval, 6-19%) in dogs without respiratory disease versus 100% (95% confidence interval, 74-100%) in those with left-sided heart failure. The low frequency and number of ultrasound lung rockets observed in dogs without respiratory disease and with radiographically normal lungs suggests that Vet BLUE will be clinically useful for the identification of canine respiratory conditions. © 2014 American College of Veterinary Radiology.

Performance Evaluation of UHF RFID Technologies for Real-Time Bus Recognition in the Taipei Bus Station

PubMed Central

Own, Chung-Ming; Lee, Da-Sheng; Wang, Ti-Ho; Wang, De-Jun; Ting, Yu-Lun

2013-01-01

Transport stations such as airports, ports, and railways have adopted blocked-type pathway management to process and control travel systems in a one-directional manner. However, this excludes highway transportation where large buses have great variability and mobility; thus, an instant influx of numerous buses increases risks and complicates station management. Focusing on Taipei Bus Station, this study employed RFID technology to develop a system platform integrated with modern information technology that has numerous characteristics. This modern information technology comprised the following systems: ultra-high frequency (UHF) radio-frequency identification (RFID), ultrasound and license number identification, and backstage graphic controls. In conclusion, the system enabled management, bus companies, and passengers to experience the national bus station's new generation technology, which provides diverse information and synchronization functions. Furthermore, this technology reached a new milestone in the energy-saving and efficiency-increasing performance of Taiwan's buses. PMID:23778192

47 CFR 2.815 - External radio frequency power amplifiers.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 1 2011-10-01 2011-10-01 false External radio frequency power amplifiers. 2.815 Section 2.815 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL FREQUENCY ALLOCATIONS AND RADIO TREATY MATTERS; GENERAL RULES AND REGULATIONS Marketing of Radio-frequency Devices § 2.815...

47 CFR 2.815 - External radio frequency power amplifiers.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false External radio frequency power amplifiers. 2.815 Section 2.815 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL FREQUENCY ALLOCATIONS AND RADIO TREATY MATTERS; GENERAL RULES AND REGULATIONS Marketing of Radio-frequency Devices § 2.815...

HIGH CURRENT RADIO FREQUENCY ION SOURCE

DOEpatents

Abdelaziz, M.E.

1963-04-01

This patent relates to a high current radio frequency ion source. A cylindrical plasma container has a coil disposed around the exterior surface thereof along the longitudinal axis. Means are provided for the injection of an unionized gas into the container and for applying a radio frequency signal to the coil whereby a radio frequency field is generated within the container parallel to the longitudinal axis thereof to ionize the injected gas. Cathode and anode means are provided for extracting transverse to the radio frequency field from an area midway between the ends of the container along the longitudinal axis thereof the ions created by said radio frequency field. (AEC)

Manual B-mode versus automated radio-frequency carotid intima-media thickness measurements.

PubMed

Dogan, Soner; Plantinga, Yvonne; Dijk, Joke M; van der Graaf, Yolanda; Grobbee, Diederick E; Bots, Michiel L

2009-10-01

Carotid intima-media thickness (CIMT) serves as an indicator of atherosclerosis and cardiovascular risk. Manual measurements of B-mode ultrasound images are the most applied method. Automated measurements with radiofrequency (RF) ultrasound have been suggested as an alternative. The aim of this study was to compare these methods in terms of risk-factor relations and associations with future events. Data from participants of the Second Manifestations of Arterial Disease (SMART) study were used. Far wall common CIMT was measured online with manual B-mode and automated RF ultrasound. Measurements were performed by a group of 6 sonographers. Risk-factor information was obtained. All participants were followed for the occurrence of vascular events (mean follow-up, 2.1 years). CIMT was related to risk factors with linear regression models and to future events with Cox proportional-hazards models. Data were available for 2,146 participants. Agreement between the methods was modest (intraclass correlation coefficient = 0.34). Risk-factor relations with age and systolic blood pressure were stronger for B-mode than for RF ultrasound. Association with future events was better for B-mode than for RF ultrasound (vascular death, 1.27 vs 1.00; ischemic stroke, 1.45 vs 1.03). In participants with CIMT < 0.9 mm (without plaque), the intraclass correlation between the measures was 0.50. In addition, in that subgroup, RF ultrasound showed a stronger association with future events than B-mode ultrasound (all events, 1.59 vs 1.09; vascular death, 1.72 vs 0.93; coronary ischemic events, 1.65 vs 1.05). The preference for either B-mode or RF measurements may be driven by the type of study population, the expected presence of local atherosclerotic abnormalities, and the main aim of the study (assessing risk factors or events). However, in this study, as in many others, the B-mode approach was shown to be robust in risk-factor relations and the prediction of events.

Ion cyclotron range of frequencies heating of plasma with small impurity production

DOEpatents

Ohkawa, Tihiro

1987-01-01

Plasma including plasma ions is magnetically confined by a magnetic field. The plasma has a defined outer surface and is intersected by resonance surfaces of respective common ion cyclotron frequency of a predetermined species of plasma ions moving in the magnetic field. A radio frequency source provides radio frequency power at a radio frequency corresponding to the ion cyclotron frequency of the predetermined species of plasma ions moving in the field at a respective said resonance surface. RF launchers coupled to the radio frequency source radiate radio frequency energy at the resonance frequency onto the respective resonance surface within the plasma from a plurality of locations located outside the plasma at such respective distances from the intersections of the respective resonance surface and the defined outer surface and at such relative phases that the resulting interference pattern provides substantially null net radio frequency energy over regions near and including substantial portions of the intersections relative to the radio frequency energy provided thereby at other portions of the respective resonance surface within the plasma.

Frequency-dependent ultrasound-induced transformation in E. coli.

PubMed

Deeks, Jeremy; Windmill, James; Agbeze-Onuma, Maduka; Kalin, Robert M; Argondizza, Peter; Knapp, Charles W

2014-12-01

Ultrasound-enhanced gene transfer (UEGT) is continuing to gain interest across many disciplines; however, very few studies investigate UEGT efficiency across a range of frequencies. Using a variable frequency generator, UEGT was tested in E. coli at six ultrasonic frequencies. Results indicate frequency can significantly influence UEGT efficiency positively and negatively. A frequency of 61 kHz improved UEGT efficiency by ~70 % higher, but 99 kHz impeded UEGT to an extent worse than no ultrasound exposure. The other four frequencies (26, 133, 174, and 190 kHz) enhanced transformation compared to no ultrasound, but efficiencies did not vary. The influence of frequency on UEGT efficiency was observed across a range of operating frequencies. It is plausible that frequency-dependent dynamics of mechanical and chemical energies released during cavitational-bubble collapse (CBC) are responsible for observed UEGT efficiencies.

Real-time Monitoring of High Intensity Focused Ultrasound (HIFU) Ablation of In Vitro Canine Livers Using Harmonic Motion Imaging for Focused Ultrasound (HMIFU).

PubMed

Grondin, Julien; Payen, Thomas; Wang, Shutao; Konofagou, Elisa E

2015-11-03

Harmonic Motion Imaging for Focused Ultrasound (HMIFU) is a technique that can perform and monitor high-intensity focused ultrasound (HIFU) ablation. An oscillatory motion is generated at the focus of a 93-element and 4.5 MHz center frequency HIFU transducer by applying a 25 Hz amplitude-modulated signal using a function generator. A 64-element and 2.5 MHz imaging transducer with 68kPa peak pressure is confocally placed at the center of the HIFU transducer to acquire the radio-frequency (RF) channel data. In this protocol, real-time monitoring of thermal ablation using HIFU with an acoustic power of 7 W on canine livers in vitro is described. HIFU treatment is applied on the tissue during 2 min and the ablated region is imaged in real-time using diverging or plane wave imaging up to 1,000 frames/second. The matrix of RF channel data is multiplied by a sparse matrix for image reconstruction. The reconstructed field of view is of 90° for diverging wave and 20 mm for plane wave imaging and the data are sampled at 80 MHz. The reconstruction is performed on a Graphical Processing Unit (GPU) in order to image in real-time at a 4.5 display frame rate. 1-D normalized cross-correlation of the reconstructed RF data is used to estimate axial displacements in the focal region. The magnitude of the peak-to-peak displacement at the focal depth decreases during the thermal ablation which denotes stiffening of the tissue due to the formation of a lesion. The displacement signal-to-noise ratio (SNRd) at the focal area for plane wave was 1.4 times higher than for diverging wave showing that plane wave imaging appears to produce better displacement maps quality for HMIFU than diverging wave imaging.

Real-time Monitoring of High Intensity Focused Ultrasound (HIFU) Ablation of In Vitro Canine Livers Using Harmonic Motion Imaging for Focused Ultrasound (HMIFU)

PubMed Central

Grondin, Julien; Payen, Thomas; Wang, Shutao; Konofagou, Elisa E.

2015-01-01

Harmonic Motion Imaging for Focused Ultrasound (HMIFU) is a technique that can perform and monitor high-intensity focused ultrasound (HIFU) ablation. An oscillatory motion is generated at the focus of a 93-element and 4.5 MHz center frequency HIFU transducer by applying a 25 Hz amplitude-modulated signal using a function generator. A 64-element and 2.5 MHz imaging transducer with 68kPa peak pressure is confocally placed at the center of the HIFU transducer to acquire the radio-frequency (RF) channel data. In this protocol, real-time monitoring of thermal ablation using HIFU with an acoustic power of 7 W on canine livers in vitro is described. HIFU treatment is applied on the tissue during 2 min and the ablated region is imaged in real-time using diverging or plane wave imaging up to 1,000 frames/second. The matrix of RF channel data is multiplied by a sparse matrix for image reconstruction. The reconstructed field of view is of 90° for diverging wave and 20 mm for plane wave imaging and the data are sampled at 80 MHz. The reconstruction is performed on a Graphical Processing Unit (GPU) in order to image in real-time at a 4.5 display frame rate. 1-D normalized cross-correlation of the reconstructed RF data is used to estimate axial displacements in the focal region. The magnitude of the peak-to-peak displacement at the focal depth decreases during the thermal ablation which denotes stiffening of the tissue due to the formation of a lesion. The displacement signal-to-noise ratio (SNRd) at the focal area for plane wave was 1.4 times higher than for diverging wave showing that plane wave imaging appears to produce better displacement maps quality for HMIFU than diverging wave imaging. PMID:26556647

Frequency sensitive mechanism in low-intensity ultrasound enhanced bioeffects

PubMed Central

Chama, Abdoulkadri; Subramanian, Anuradha; Viljoen, Hendrik J.

2017-01-01

This study presents two novel theoretical models to elucidate frequency sensitive nuclear mechanisms in low-intensity ultrasound enhanced bioeffects. In contrast to the typical 1.5 MHz pulsed ultrasound regime, our group previously experimentally confirmed that ultrasound stimulation of anchored chondrocytes at resonant frequency maximized gene expression of load inducible genes which are regulatory markers for cellular response to external stimuli. However, ERK phosphorylation displayed no frequency dependency, suggesting that the biochemical mechanisms involved in enhanced gene expression is downstream of ERK phosphorylation. To elucidate such underlying mechanisms, this study presents a theoretical model of an anchored cell, representing an in vitro chondrocyte, in an ultrasound field. The model results showed that the mechanical energy storage is maximized at the chondrocyte’s resonant frequency and the energy density in the nucleus is almost twice as high as in the cytoplasm. Next, a mechanochemical model was developed to link the mechanical stimulation of ultrasound and the increased mechanical energy density in the nucleus to the downstream targets of the ERK pathway. This study showed for the first time that ultrasound stimulation induces frequency dependent gene expression as a result of altered rates of transcription factors binding to chromatin. PMID:28763448

Ultrasound speckle tracking for radial, longitudinal and circumferential strain estimation of the carotid artery--an in vitro validation via sonomicrometry using clinical and high-frequency ultrasound.

PubMed

Larsson, Matilda; Heyde, Brecht; Kremer, Florence; Brodin, Lars-Åke; D'hooge, Jan

2015-02-01

Ultrasound speckle tracking for carotid strain assessment has in the past decade gained interest in studies of arterial stiffness and cardiovascular diseases. The aim of this study was to validate and directly contrast carotid strain assessment by speckle tracking applied on clinical and high-frequency ultrasound images in vitro. Four polyvinyl alcohol phantoms mimicking the carotid artery were constructed with different mechanical properties and connected to a pump generating carotid flow profiles. Gray-scale ultrasound long- and short-axis images of the phantoms were obtained using a standard clinical ultrasound system, Vivid 7 (GE Healthcare, Horten, Norway) and a high-frequency ultrasound system, Vevo 2100 (FUJIFILM, VisualSonics, Toronto, Canada) with linear-array transducers (12L/MS250). Radial, longitudinal and circumferential strains were estimated using an in-house speckle tracking algorithm and compared with reference strain acquired by sonomicrometry. Overall, the estimated strain corresponded well with the reference strain. The correlation between estimated peak strain in clinical ultrasound images and reference strain was 0.91 (p<0.001) for radial strain, 0.73 (p<0.001) for longitudinal strain and 0.90 (p<0.001) for circumferential strain and for high-frequency ultrasound images 0.95 (p<0.001) for radial strain, 0.93 (p<0.001) for longitudinal strain and 0.90 (p<0.001) for circumferential strain. A significant larger bias and root mean square error was found for circumferential strain estimation on clinical ultrasound images compared to high frequency ultrasound images, but no significant difference in bias and root mean square error was found for radial and longitudinal strain when comparing estimation on clinical and high-frequency ultrasound images. The agreement between sonomicrometry and speckle tracking demonstrates that carotid strain assessment by ultrasound speckle tracking is feasible. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

Harmonic motion imaging for abdominal tumor detection and high-intensity focused ultrasound ablation monitoring: an in vivo feasibility study in a transgenic mouse model of pancreatic cancer.

PubMed

Chen, Hong; Hou, Gary Y; Han, Yang; Payen, Thomas; Palermo, Carmine F; Olive, Kenneth P; Konofagou, Elisa E

2015-09-01

Harmonic motion imaging (HMI) is a radiationforce- based elasticity imaging technique that tracks oscillatory tissue displacements induced by sinusoidal ultrasonic radiation force to assess the resulting oscillatory displacement denoting the underlying tissue stiffness. The objective of this study was to evaluate the feasibility of HMI in pancreatic tumor detection and high-intensity focused ultrasound (HIFU) treatment monitoring. The HMI system consisted of a focused ultrasound transducer, which generated sinusoidal radiation force to induce oscillatory tissue motion at 50 Hz, and a diagnostic ultrasound transducer, which detected the axial tissue displacements based on acquired radio-frequency signals using a 1-D cross-correlation algorithm. For pancreatic tumor detection, HMI images were generated for pancreatic tumors in transgenic mice and normal pancreases in wild-type mice. The obtained HMI images showed a high contrast between normal and malignant pancreases with an average peak-to-peak HMI displacement ratio of 3.2. Histological analysis showed that no tissue damage was associated with HMI when it was used for the sole purpose of elasticity imaging. For pancreatic tumor ablation monitoring, the focused ultrasound transducer was operated at a higher acoustic power and longer pulse length than that used in tumor detection to simultaneously induce HIFU thermal ablation and oscillatory tissue displacements, allowing HMI monitoring without interrupting tumor ablation. HMI monitoring of HIFU ablation found significant decreases in the peak-to-peak HMI displacements before and after HIFU ablation with a reduction rate ranging from 15.8% to 57.0%. The formation of thermal lesions after HIFU exposure was confirmed by histological analysis. This study demonstrated the feasibility of HMI in abdominal tumor detection and HIFU ablation monitoring.

Using reconstructed IVUS images for coronary plaque classification.

PubMed

Caballero, Karla L; Barajas, Joel; Pujol, Oriol; Rodriguez, Oriol; Radeva, Petia

2007-01-01

Coronary plaque rupture is one of the principal causes of sudden death in western societies. Reliable diagnostic of the different plaque types are of great interest for the medical community the predicting their evolution and applying an effective treatment. To achieve this, a tissue classification must be performed. Intravascular Ultrasound (IVUS) represents a technique to explore the vessel walls and to observe its histological properties. In this paper, a method to reconstruct IVUS images from the raw Radio Frequency (RF) data coming from ultrasound catheter is proposed. This framework offers a normalization scheme to compare accurately different patient studies. The automatic tissue classification is based on texture analysis and Adapting Boosting (Adaboost) learning technique combined with Error Correcting Output Codes (ECOC). In this study, 9 in-vivo cases are reconstructed with 7 different parameter set. This method improves the classification rate based on images, yielding a 91% of well-detected tissue using the best parameter set. It also reduces the inter-patient variability compared with the analysis of DICOM images, which are obtained from the commercial equipment.

Battery management system with distributed wireless sensors

DOEpatents

Farmer, Joseph C.; Bandhauer, Todd M.

2016-02-23

A system for monitoring parameters of an energy storage system having a multiplicity of individual energy storage cells. A radio frequency identification and sensor unit is connected to each of the individual energy storage cells. The radio frequency identification and sensor unit operates to sense the parameter of each individual energy storage cell and provides radio frequency transmission of the parameters of each individual energy storage cell. A management system monitors the radio frequency transmissions from the radio frequency identification and sensor units for monitoring the parameters of the energy storage system.

Advanced capability RFID system

DOEpatents

Gilbert, Ronald W.; Steele, Kerry D.; Anderson, Gordon A.

2007-09-25

A radio-frequency transponder device having an antenna circuit configured to receive radio-frequency signals and to return modulated radio-frequency signals via continuous wave backscatter, a modulation circuit coupled to the antenna circuit for generating the modulated radio-frequency signals, and a microprocessor coupled to the antenna circuit and the modulation circuit and configured to receive and extract operating power from the received radio-frequency signals and to monitor inputs on at least one input pin and to generate responsive signals to the modulation circuit for modulating the radio-frequency signals. The microprocessor can be configured to generate output signals on output pins to associated devices for controlling the operation thereof. Electrical energy can be extracted and stored in an optional electrical power storage device.

The Lens of Power: Aerial Reconnaissance and Diplomacy in the Airpower Century

DTIC Science & Technology

2013-01-01

participated in the search for survivors and wreckage, at one point receiving an American radio from a nearby US ship to better communicate between... Frequency ) radio distress frequency , although it is not clear exactly what frequency he was using. VHF is Very High Frequency radio ; UHF is Ultra High... Frequency radio . 121.5 and 243.0 remain the respective VHF and UHF international distress frequencies today. Osborn, Born to Fly: The Untold Story

Low-frequency quantitative ultrasound imaging of cell death in vivo

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sadeghi-Naini, Ali; Falou, Omar; Czarnota, Gregory J.

Purpose: Currently, no clinical imaging modality is used routinely to assess tumor response to cancer therapies within hours to days of the delivery of treatment. Here, the authors demonstrate the efficacy of ultrasound at a clinically relevant frequency to quantitatively detect changes in tumors in response to cancer therapies using preclinical mouse models.Methods: Conventional low-frequency and corresponding high-frequency ultrasound (ranging from 4 to 28 MHz) were used along with quantitative spectroscopic and signal envelope statistical analyses on data obtained from xenograft tumors treated with chemotherapy, x-ray radiation, as well as a novel vascular targeting microbubble therapy.Results: Ultrasound-based spectroscopic biomarkers indicatedmore » significant changes in cell-death associated parameters in responsive tumors. Specifically changes in the midband fit, spectral slope, and 0-MHz intercept biomarkers were investigated for different types of treatment and demonstrated cell-death related changes. The midband fit and 0-MHz intercept biomarker derived from low-frequency data demonstrated increases ranging approximately from 0 to 6 dBr and 0 to 8 dBr, respectively, depending on treatments administrated. These data paralleled results observed for high-frequency ultrasound data. Statistical analysis of ultrasound signal envelope was performed as an alternative method to obtain histogram-based biomarkers and provided confirmatory results. Histological analysis of tumor specimens indicated up to 61% cell death present in the tumors depending on treatments administered, consistent with quantitative ultrasound findings indicating cell death. Ultrasound-based spectroscopic biomarkers demonstrated a good correlation with histological morphological findings indicative of cell death (r{sup 2}= 0.71, 0.82; p < 0.001).Conclusions: In summary, the results provide preclinical evidence, for the first time, that quantitative ultrasound used at a clinically relevant frequency, in addition to high-frequency ultrasound, can detect tissue changes associated with cell death in vivo in response to cancer treatments.« less

Elastography using multi-stream GPU: an application to online tracked ultrasound elastography, in-vivo and the da Vinci Surgical System.

PubMed

Deshmukh, Nishikant P; Kang, Hyun Jae; Billings, Seth D; Taylor, Russell H; Hager, Gregory D; Boctor, Emad M

2014-01-01

A system for real-time ultrasound (US) elastography will advance interventions for the diagnosis and treatment of cancer by advancing methods such as thermal monitoring of tissue ablation. A multi-stream graphics processing unit (GPU) based accelerated normalized cross-correlation (NCC) elastography, with a maximum frame rate of 78 frames per second, is presented in this paper. A study of NCC window size is undertaken to determine the effect on frame rate and the quality of output elastography images. This paper also presents a novel system for Online Tracked Ultrasound Elastography (O-TRuE), which extends prior work on an offline method. By tracking the US probe with an electromagnetic (EM) tracker, the system selects in-plane radio frequency (RF) data frames for generating high quality elastograms. A novel method for evaluating the quality of an elastography output stream is presented, suggesting that O-TRuE generates more stable elastograms than generated by untracked, free-hand palpation. Since EM tracking cannot be used in all systems, an integration of real-time elastography and the da Vinci Surgical System is presented and evaluated for elastography stream quality based on our metric. The da Vinci surgical robot is outfitted with a laparoscopic US probe, and palpation motions are autonomously generated by customized software. It is found that a stable output stream can be achieved, which is affected by both the frequency and amplitude of palpation. The GPU framework is validated using data from in-vivo pig liver ablation; the generated elastography images identify the ablated region, outlined more clearly than in the corresponding B-mode US images.

Elastography Using Multi-Stream GPU: An Application to Online Tracked Ultrasound Elastography, In-Vivo and the da Vinci Surgical System

PubMed Central

Deshmukh, Nishikant P.; Kang, Hyun Jae; Billings, Seth D.; Taylor, Russell H.; Hager, Gregory D.; Boctor, Emad M.

2014-01-01

A system for real-time ultrasound (US) elastography will advance interventions for the diagnosis and treatment of cancer by advancing methods such as thermal monitoring of tissue ablation. A multi-stream graphics processing unit (GPU) based accelerated normalized cross-correlation (NCC) elastography, with a maximum frame rate of 78 frames per second, is presented in this paper. A study of NCC window size is undertaken to determine the effect on frame rate and the quality of output elastography images. This paper also presents a novel system for Online Tracked Ultrasound Elastography (O-TRuE), which extends prior work on an offline method. By tracking the US probe with an electromagnetic (EM) tracker, the system selects in-plane radio frequency (RF) data frames for generating high quality elastograms. A novel method for evaluating the quality of an elastography output stream is presented, suggesting that O-TRuE generates more stable elastograms than generated by untracked, free-hand palpation. Since EM tracking cannot be used in all systems, an integration of real-time elastography and the da Vinci Surgical System is presented and evaluated for elastography stream quality based on our metric. The da Vinci surgical robot is outfitted with a laparoscopic US probe, and palpation motions are autonomously generated by customized software. It is found that a stable output stream can be achieved, which is affected by both the frequency and amplitude of palpation. The GPU framework is validated using data from in-vivo pig liver ablation; the generated elastography images identify the ablated region, outlined more clearly than in the corresponding B-mode US images. PMID:25541954

Mechanotransduction of Ultrasound is Frequency Dependent Below the Cavitation Threshold

PubMed Central

Louw, Tobias M.; Budhiraja, Gaurav; Viljoen, Hendrik J.; Subramanian, Anuradha

2013-01-01

This study provides evidence that low-intensity ultrasound directly affects nuclear processes, and the magnitude of the effect varies with frequency. In particular, we show that the transcriptional induction of first load-inducible genes, which is independent of new protein synthesis, is frequency dependent. Bovine chondrocytes were exposed to low-intensity below the cavitational threshold) ultrasound at 2,5 and 8 MHz. Ultrasound elevated the expression of early response genes c-Fos, c-Jun and c-Myc, maximized at 5 MHz. The phosphorylated ERK inhibitor PD98059 abrogated any increase in c-series gene expression, suggesting that signaling occurs via the MAPPK/ERK pathway. However, phosphorylated ERK levels did not change with ultrasound frequency, indicating that processes downstream of ERK phosphorylation (such as nuclear transport and chromatin reorganization) respond to ultrasound with frequency dependence. A quantitative, biphasic mathematical model based on Biot theory predicted that cytoplasmic and nuclear stress is maximized at 5.2 ± 0.8 MHz for a chondrocyte, confirming experimental measurements. PMID:23562015

47 CFR 76.616 - Operation near certain aeronautical and marine emergency radio frequencies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... emergency radio frequencies. 76.616 Section 76.616 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Technical Standards § 76.616 Operation near certain aeronautical and marine emergency radio frequencies. (a) The transmission...

Quantification of ultrasonic texture intra-heterogeneity via volumetric stochastic modeling for tissue characterization.

PubMed

Al-Kadi, Omar S; Chung, Daniel Y F; Carlisle, Robert C; Coussios, Constantin C; Noble, J Alison

2015-04-01

Intensity variations in image texture can provide powerful quantitative information about physical properties of biological tissue. However, tissue patterns can vary according to the utilized imaging system and are intrinsically correlated to the scale of analysis. In the case of ultrasound, the Nakagami distribution is a general model of the ultrasonic backscattering envelope under various scattering conditions and densities where it can be employed for characterizing image texture, but the subtle intra-heterogeneities within a given mass are difficult to capture via this model as it works at a single spatial scale. This paper proposes a locally adaptive 3D multi-resolution Nakagami-based fractal feature descriptor that extends Nakagami-based texture analysis to accommodate subtle speckle spatial frequency tissue intensity variability in volumetric scans. Local textural fractal descriptors - which are invariant to affine intensity changes - are extracted from volumetric patches at different spatial resolutions from voxel lattice-based generated shape and scale Nakagami parameters. Using ultrasound radio-frequency datasets we found that after applying an adaptive fractal decomposition label transfer approach on top of the generated Nakagami voxels, tissue characterization results were superior to the state of art. Experimental results on real 3D ultrasonic pre-clinical and clinical datasets suggest that describing tumor intra-heterogeneity via this descriptor may facilitate improved prediction of therapy response and disease characterization. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

Power strain imaging based on vibro-elastography techniques

NASA Astrophysics Data System (ADS)

Wen, Xu; Salcudean, S. E.

2007-03-01

This paper describes a new ultrasound elastography technique, power strain imaging, based on vibro-elastography (VE) techniques. With this method, tissue is compressed by a vibrating actuator driven by low-pass or band-pass filtered white noise, typically in the 0-20 Hz range. Tissue displacements at different spatial locations are estimated by correlation-based approaches on the raw ultrasound radio frequency signals and recorded in time sequences. The power spectra of these time sequences are computed by Fourier spectral analysis techniques. As the average of the power spectrum is proportional to the squared amplitude of the tissue motion, the square root of the average power over the range of excitation frequencies is used as a measure of the tissue displacement. Then tissue strain is determined by the least squares estimation of the gradient of the displacement field. The computation of the power spectra of the time sequences can be implemented efficiently by using Welch's periodogram method with moving windows or with accumulative windows with a forgetting factor. Compared to the transfer function estimation originally used in VE, the computation of cross spectral densities is not needed, which saves both the memory and computational times. Phantom experiments demonstrate that the proposed method produces stable and operator-independent strain images with high signal-to-noise ratio in real time. This approach has been also tested on a few patient data of the prostate region, and the results are encouraging.

High-energy sources at low radio frequency: the Murchison Widefield Array view of Fermi blazars

DOE PAGES

Giroletti, M.; Massaro, F.; D’Abrusco, R.; ...

2016-04-01

Low-frequency radio arrays are opening a new window for the study of the sky, both to study new phenomena and to better characterize known source classes. Being flat-spectrum sources, blazars are so far poorly studied at low radio frequencies. In this paper, we characterize the spectral properties of the blazar population at low radio frequency, compare the radio and high-energy properties of the gamma-ray blazar population, and search for radio counterparts of unidentified gamma-ray sources. We cross-correlated the 6100 deg 2 Murchison Widefield Array Commissioning Survey catalogue with the Roma blazar catalogue, the third catalogue of active galactic nuclei detectedmore » by Fermi-LAT, and the unidentified members of the entire third catalogue of gamma-ray sources detected by Fermi-LAT. When available, we also added high-frequency radio data from the Australia Telescope 20 GHz catalogue. We find low-frequency counterparts for 186 out of 517 (36%) blazars, 79 out of 174 (45%) gamma-ray blazars, and 8 out of 73 (11%) gamma-ray blazar candidates. The mean low-frequency (120–180 MHz) blazar spectral index is (α low) = 0.57 ± 0.02: blazar spectra are flatter than the rest of the population of low-frequency sources, but are steeper than at ~GHz frequencies. Low-frequency radio flux density and gamma-ray energy flux display a mildly significant and broadly scattered correlation. Ten unidentified gamma-ray sources have a (probably fortuitous) positional match with low radio frequency sources. Low-frequency radio astronomy provides important information about sources with a flat radio spectrum and high energy. However, the relatively low sensitivity of the present surveys still misses a significant fraction of these objects. Finally, upcoming deeper surveys, such as the GaLactic and Extragalactic All-Sky MWA (GLEAM) survey, will provide further insight into this population.« less

High-energy sources at low radio frequency: the Murchison Widefield Array view of Fermi blazars

DOE Office of Scientific and Technical Information (OSTI.GOV)

Giroletti, M.; Massaro, F.; D’Abrusco, R.

Low-frequency radio arrays are opening a new window for the study of the sky, both to study new phenomena and to better characterize known source classes. Being flat-spectrum sources, blazars are so far poorly studied at low radio frequencies. In this paper, we characterize the spectral properties of the blazar population at low radio frequency, compare the radio and high-energy properties of the gamma-ray blazar population, and search for radio counterparts of unidentified gamma-ray sources. We cross-correlated the 6100 deg 2 Murchison Widefield Array Commissioning Survey catalogue with the Roma blazar catalogue, the third catalogue of active galactic nuclei detectedmore » by Fermi-LAT, and the unidentified members of the entire third catalogue of gamma-ray sources detected by Fermi-LAT. When available, we also added high-frequency radio data from the Australia Telescope 20 GHz catalogue. We find low-frequency counterparts for 186 out of 517 (36%) blazars, 79 out of 174 (45%) gamma-ray blazars, and 8 out of 73 (11%) gamma-ray blazar candidates. The mean low-frequency (120–180 MHz) blazar spectral index is (α low) = 0.57 ± 0.02: blazar spectra are flatter than the rest of the population of low-frequency sources, but are steeper than at ~GHz frequencies. Low-frequency radio flux density and gamma-ray energy flux display a mildly significant and broadly scattered correlation. Ten unidentified gamma-ray sources have a (probably fortuitous) positional match with low radio frequency sources. Low-frequency radio astronomy provides important information about sources with a flat radio spectrum and high energy. However, the relatively low sensitivity of the present surveys still misses a significant fraction of these objects. Finally, upcoming deeper surveys, such as the GaLactic and Extragalactic All-Sky MWA (GLEAM) survey, will provide further insight into this population.« less

Improved Anatomical Specificity of Non-invasive Neuro-stimulation by High Frequency (5 MHz) Ultrasound

NASA Astrophysics Data System (ADS)

Li, Guo-Feng; Zhao, Hui-Xia; Zhou, Hui; Yan, Fei; Wang, Jing-Yao; Xu, Chang-Xi; Wang, Cong-Zhi; Niu, Li-Li; Meng, Long; Wu, Song; Zhang, Huai-Ling; Qiu, Wei-Bao; Zheng, Hai-Rong

2016-04-01

Low frequency ultrasound (<1 MHz) has been demonstrated to be a promising approach for non-invasive neuro-stimulation. However, the focal width is limited to be half centimeter scale. Minimizing the stimulation region with higher frequency ultrasound will provide a great opportunity to expand its application. This study first time examines the feasibility of using high frequency (5 MHz) ultrasound to achieve neuro-stimulation in brain, and verifies the anatomical specificity of neuro-stimulation in vivo. 1 MHz and 5 MHz ultrasound stimulation were evaluated in the same group of mice. Electromyography (EMG) collected from tail muscles together with the motion response videos were analyzed for evaluating the stimulation effects. Our results indicate that 5 MHz ultrasound can successfully achieve neuro-stimulation. The equivalent diameter (ED) of the stimulation region with 5 MHz ultrasound (0.29 ± 0.08 mm) is significantly smaller than that with 1 MHz (0.83 ± 0.11 mm). The response latency of 5 MHz ultrasound (45 ± 31 ms) is also shorter than that of 1 MHz ultrasound (208 ± 111 ms). Consequently, high frequency (5 MHz) ultrasound can successfully activate the brain circuits in mice. It provides a smaller stimulation region, which offers improved anatomical specificity for neuro-stimulation in a non-invasive manner.

Radio frequency identification-enabled capabilities in a healthcare context: An exploratory study.

PubMed

Hornyak, Rob; Lewis, Mark; Sankaranarayan, Balaji

2016-09-01

Increasingly, the adoption and use of radio frequency identification systems in hospital settings is gaining prominence. However, despite the transformative impact that radio frequency identification has in healthcare settings, few studies have examined how and why this change may occur. The purpose of this study is to systematically understand how radio frequency identification can transform work practices in an operational process that directly impacts cost and operational efficiency and indirectly contributes to impacting patient safety and quality of care. We leverage an interdisciplinary framework to explore the contextual characteristics that shape the assimilation of radio frequency identification in healthcare settings. By linking the use of radio frequency identification with specific contextual dimensions in healthcare settings, we provide a data-driven account of how and why radio frequency identification can be useful in inventory management in this setting. In doing so, we also contribute to recent work by information systems scholars who argue for a reconfiguration of conventional assumptions regarding the role of technology in contemporary organizations. © The Author(s) 2015.

Modelling and restoration of ultrasonic phased-array B-scan images.

PubMed

Ardouin, J P; Venetsanopoulos, A N

1985-10-01

A model is presented for the radio-frequency image produced by a B-scan (pulse-echo) ultrasound imaging system using a phased-array transducer. This type of scanner is widely used for real-time heart imaging. The model allows for dynamic focusing as well as an acoustic lens focusing the beam in the elevation plane. A result of the model is an expression to compute the space-variant point spread function (PSF) of the system. This is made possible by the use of a combination of Fresnel and Fraunhoffer approximations which are valid in the range of interest for practical applications. The PSF is used to design restoration filters in order to improve image resolution. The filters are then applied to experimental images of wires.

Quality properties of pre- and post-rigor beef muscle after interventions with high frequency ultrasound.

PubMed

Sikes, Anita L; Mawson, Raymond; Stark, Janet; Warner, Robyn

2014-11-01

The delivery of a consistent quality product to the consumer is vitally important for the food industry. The aim of this study was to investigate the potential for using high frequency ultrasound applied to pre- and post-rigor beef muscle on the metabolism and subsequent quality. High frequency ultrasound (600kHz at 48kPa and 65kPa acoustic pressure) applied to post-rigor beef striploin steaks resulted in no significant effect on the texture (peak force value) of cooked steaks as measured by a Tenderometer. There was no added benefit of ultrasound treatment above that of the normal ageing process after ageing of the steaks for 7days at 4°C. Ultrasound treatment of post-rigor beef steaks resulted in a darkening of fresh steaks but after ageing for 7days at 4°C, the ultrasound-treated steaks were similar in colour to that of the aged, untreated steaks. High frequency ultrasound (2MHz at 48kPa acoustic pressure) applied to pre-rigor beef neck muscle had no effect on the pH, but the calculated exhaustion factor suggested that there was some effect on metabolism and actin-myosin interaction. However, the resultant texture of cooked, ultrasound-treated muscle was lower in tenderness compared to the control sample. After ageing for 3weeks at 0°C, the ultrasound-treated samples had the same peak force value as the control. High frequency ultrasound had no significant effect on the colour parameters of pre-rigor beef neck muscle. This proof-of-concept study showed no effect of ultrasound on quality but did indicate that the application of high frequency ultrasound to pre-rigor beef muscle shows potential for modifying ATP turnover and further investigation is warranted. Crown Copyright © 2014. Published by Elsevier B.V. All rights reserved.

Effects of multi-frequency power ultrasound on the enzymolysis and structural characteristics of corn gluten meal.

PubMed

Jin, Jian; Ma, Haile; Wang, Kai; Yagoub, Abu El-Gasim A; Owusu, John; Qu, Wenjuan; He, Ronghai; Zhou, Cunshan; Ye, Xiaofei

2015-05-01

The aim of this study was to investigate the effect of multi-frequency power ultrasound (sweeping frequency and pulsed ultrasound (SFPU) and sequential dual frequency ultrasound (SDFU)) on the enzymolysis of corn gluten meal (CGM) and on the structures of the major protein fractions (zein, glutelin) of CGM. The results showed that multi-frequency power ultrasound pretreatments improved significantly (P<0.05) the degree of hydrolysis and conversion rate of CGM. The changes in UV-Vis spectra, fluorescence emission spectra, surface hydrophobicity (H0), and the content of SH and SS groups indicated unfolding of zein and glutelin by ultrasound. The circular dichroism analysis showed that both pretreatments decreased α-helix and increased β-sheet of glutelin. The SFPU pretreatment had little impact on the secondary structure of zein, while the SDFU increased the α-helix and decreased the β-sheet remarkably. Scanning electron microscope indicated that both pretreatments destroyed the microstructures of glutelin and CGM, reduced the particle size of zein despite that the SDFU induced aggregation was observed. In conclusion, multi-frequency power ultrasound pretreatment is an efficient method in protein proteolysis due to its sonochemistry effect on the molecular conformation as well as on the microstructure of protein. Copyright © 2014 Elsevier B.V. All rights reserved.

Influence of mixing and ultrasound frequency on antisolvent crystallisation of sodium chloride.

PubMed

Lee, Judy; Ashokkumar, Muthupandian; Kentish, Sandra E

2014-01-01

Ultrasound is known to promote nucleation of crystals and produce a narrower size distribution in a controlled and reproducible manner for the crystallisation process. Although there are various theories that suggest cavitation bubbles are responsible for sonocrystallisation, most studies use power ultrasonic horns that generate both intense shear and cavitation and this can mask the role that cavitation bubbles play. High frequency ultrasound from a plate transducer can be used to examine the effect of cavitation bubbles without the intense shear effect. This study reports the crystal size and morphology with various mixing speeds and ultrasound frequencies. The results show high frequency ultrasound produced sodium chloride crystals of similar size distribution as an ultrasonic horn. In addition, ultrasound generated sodium chloride crystals having a more symmetrical cubic structure compared to crystals produced by a high shear mixer. Copyright © 2013 Elsevier B.V. All rights reserved.

Increased Anatomical Specificity of Neuromodulation via Modulated Focused Ultrasound

PubMed Central

Mehić, Edin; Xu, Julia M.; Caler, Connor J.; Coulson, Nathaniel K.; Moritz, Chet T.; Mourad, Pierre D.

2014-01-01

Transcranial ultrasound can alter brain function transiently and nondestructively, offering a new tool to study brain function now and inform future therapies. Previous research on neuromodulation implemented pulsed low-frequency (250–700 kHz) ultrasound with spatial peak temporal average intensities (ISPTA) of 0.1–10 W/cm2. That work used transducers that either insonified relatively large volumes of mouse brain (several mL) with relatively low-frequency ultrasound and produced bilateral motor responses, or relatively small volumes of brain (on the order of 0.06 mL) with relatively high-frequency ultrasound that produced unilateral motor responses. This study seeks to increase anatomical specificity to neuromodulation with modulated focused ultrasound (mFU). Here, ‘modulated’ means modifying a focused 2-MHz carrier signal dynamically with a 500-kHz signal as in vibro-acoustography, thereby creating a low-frequency but small volume (approximately 0.015 mL) source of neuromodulation. Application of transcranial mFU to lightly anesthetized mice produced various motor movements with high spatial selectivity (on the order of 1 mm) that scaled with the temporal average ultrasound intensity. Alone, mFU and focused ultrasound (FUS) each induced motor activity, including unilateral motions, though anatomical location and type of motion varied. Future work should include larger animal models to determine the relative efficacy of mFU versus FUS. Other studies should determine the biophysical processes through which they act. Also of interest is exploration of the potential research and clinical applications for targeted, transcranial neuromodulation created by modulated focused ultrasound, especially mFU’s ability to produce compact sources of ultrasound at the very low frequencies (10–100s of Hertz) that are commensurate with the natural frequencies of the brain. PMID:24504255

High-performance radio frequency transistors based on diameter-separated semiconducting carbon nanotubes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cao, Yu; Che, Yuchi; Zhou, Chongwu, E-mail: chongwuz@usc.edu

In this paper, we report the high-performance radio-frequency transistors based on the single-walled semiconducting carbon nanotubes with a refined average diameter of ∼1.6 nm. These diameter-separated carbon nanotube transistors show excellent transconductance of 55 μS/μm and desirable drain current saturation with an output resistance of ∼100 KΩ μm. An exceptional radio-frequency performance is also achieved with current gain and power gain cut-off frequencies of 23 GHz and 20 GHz (extrinsic) and 65 GHz and 35 GHz (intrinsic), respectively. These radio-frequency metrics are among the highest reported for the carbon nanotube thin-film transistors. This study provides demonstration of radio frequency transistors based on carbon nanotubes with tailoredmore » diameter distributions, which will guide the future application of carbon nanotubes in radio-frequency electronics.« less

47 CFR Appendix 1 to Subpart E of... - Glossary of Terms

Code of Federal Regulations, 2013 CFR

2013-10-01

... typically includes a frequency monitoring system that initiates a MedRadio communications session. MedRadio... Part 95 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO... station authorized in the CB. Channel frequencies. Reference frequencies from which the carrier frequency...

47 CFR Appendix 1 to Subpart E of... - Glossary of Terms

Code of Federal Regulations, 2014 CFR

2014-10-01

... typically includes a frequency monitoring system that initiates a MedRadio communications session. MedRadio... Part 95 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO... station authorized in the CB. Channel frequencies. Reference frequencies from which the carrier frequency...

TRI-SERVICE ELF COMMUNICATIONS - VOL. II, BIBLIOGRAPHY.

DTIC Science & Technology

BIBLIOGRAPHIES, UNDERGROUND ANTENNAS , ELECTRICAL RESISTANCE, UNDERGROUND , COSTS, VERY LOW FREQUENCY, LOW FREQUENCY, PROPAGATION, NOISE(RADIO)....EXTREMELY LOW FREQUENCY), (*COMMAND AND CONTROL SYSTEMS, COMMUNICATION AND RADIO SYSTEMS), (* COMMUNICATION AND RADIO SYSTEMS, MILITARY RESEARCH

40 CFR 60.721 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... include conductive sensitizers or electromagnetic interference/radio frequency interference shielding.... Electromagnetic interference/radio frequency interference (EMI/RFI) shielding coating means a conductive coating... coating is applied, not including conductive sensitizers or electromagnetic interference/radio frequency...

40 CFR 60.721 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... include conductive sensitizers or electromagnetic interference/radio frequency interference shielding.... Electromagnetic interference/radio frequency interference (EMI/RFI) shielding coating means a conductive coating... coating is applied, not including conductive sensitizers or electromagnetic interference/radio frequency...

40 CFR 60.721 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... include conductive sensitizers or electromagnetic interference/radio frequency interference shielding.... Electromagnetic interference/radio frequency interference (EMI/RFI) shielding coating means a conductive coating... coating is applied, not including conductive sensitizers or electromagnetic interference/radio frequency...

40 CFR 60.721 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... include conductive sensitizers or electromagnetic interference/radio frequency interference shielding.... Electromagnetic interference/radio frequency interference (EMI/RFI) shielding coating means a conductive coating... coating is applied, not including conductive sensitizers or electromagnetic interference/radio frequency...

40 CFR 60.721 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... include conductive sensitizers or electromagnetic interference/radio frequency interference shielding.... Electromagnetic interference/radio frequency interference (EMI/RFI) shielding coating means a conductive coating... coating is applied, not including conductive sensitizers or electromagnetic interference/radio frequency...

Radio-frequency measurement in semiconductor quantum computation

NASA Astrophysics Data System (ADS)

Han, TianYi; Chen, MingBo; Cao, Gang; Li, HaiOu; Xiao, Ming; Guo, GuoPing

2017-05-01

Semiconductor quantum dots have attracted wide interest for the potential realization of quantum computation. To realize efficient quantum computation, fast manipulation and the corresponding readout are necessary. In the past few decades, considerable progress of quantum manipulation has been achieved experimentally. To meet the requirements of high-speed readout, radio-frequency (RF) measurement has been developed in recent years, such as RF-QPC (radio-frequency quantum point contact) and RF-DGS (radio-frequency dispersive gate sensor). Here we specifically demonstrate the principle of the radio-frequency reflectometry, then review the development and applications of RF measurement, which provides a feasible way to achieve high-bandwidth readout in quantum coherent control and also enriches the methods to study these artificial mesoscopic quantum systems. Finally, we prospect the future usage of radio-frequency reflectometry in scaling-up of the quantum computing models.

High Intensity Focused Ultrasound (HIFU) Based Thrombolysis Using Multiple Frequency Excitations

NASA Astrophysics Data System (ADS)

Suo, Dingjie

High intensity focused ultrasound (HIFU) based thrombolysis has emerged as a promising drug-free approach for ischemic stroke treatment. The large amount of acoustic power required by this approach, however, poses a critical challenge to the future clinical translation because of the potential thermal damages. In this dissertation, multi-frequency acoustic waves at MHz range (near 1.5 MHz) were first introduced as HIFU excitations to reduce the required treatment power as well as the treatment time. It was found that dual-frequency thrombolysis efficiency was statistically better than that of single-frequency, under the same acoustic power and excitation condition. Microbubbles (MBs) combined with dual-frequency focused ultrasound (DFFU) for thrombolysis in vitro was then proposed to further reduce the power required. MBs are widely used in therapeutic ultrasound thrombolysis due to the nonlinear characteristics of their harmonic responses, coalescence and cavitation effects, which could further enhance efficiency. It was shown in this study that MBs, with sufficient concentration, could significantly lower the power threshold for thrombolysis for both DFFU and single-frequency focused ultrasound (SFFU). MBs mediated DFFU thrombolysis were then studied with a flow system that mimicked the blood flow in the artery of the brain. It was found that the cavitation threshold of a DFFU excitation yielded a lower level than that of a SFFU excitation. All the experimental results indicated that multi-frequency ultrasound could improve the thrombolysis efficiency. However, this was not well established numerically. Hence, a numerical investigation on the inertial cavitation threshold of MBs under multifrequency ultrasound irradiation was then investigated to confirm the benefit of using multi-frequency ultrasound for various applications. The main contribution and findings of this dissertation are as follows: 1) For the HIFU along study, when varying the acoustic power while fixing the duty cycle at 5%, it was found that almost 30% of the power can be saved by dual frequency ultrasound to achieve the same thrombolysis efficiency. In the experiment where the duty cycle was increased from 0.5% to 10%, it was shown that dual-frequency ultrasound can achieve the same thrombolysis efficiency with only half of the duty cycle of singlefrequency. Dual-frequency ultrasound could also accelerate the thrombolysis by a factor of 2-4 as demonstrated in this study. The measured cavitation doses of dual-frequency and triple-frequency excitations were at about the same level, both significantly higher than that of single-frequency. 2) For the MBs mediated thrombolysis study, SFFU needed about 96%-156% higher energy to achieve the same thrombolysis efficiency as that of DFFU. The thrombolysis efficiency was also found to increase with the duty cycle. The measured cavitation signals reveal that the enhanced inertial cavitation may contribute to the improved thrombolysis under DFFU and MBs. By adding the flow system, the inertial cavitation was higher than the static model. One reason could be the dissolution of MBs into the flow that lowered the concentration of MBs by a significant amount. In both cases, the inertial cavitation thresh holds of DFFU were lower than SFFU. 3) For the numerical study, we investigated the inertial cavitation threshold of MBs under multi-frequency ultrasound irradiation. The relationships between the cavitation threshold and MB size at various frequencies and in different media were investigated. The results for single, dual and triple frequency sonication showed that inertial cavitation thresholds can be reduced by introducing additional frequencies, which was consistent with previous experimental work. In addition, no significant difference was observed between dual frequency sonication with various frequency differences. This study also provided a possible route for optimizing ultrasound excitations for initiating inertial cavitation.

Ultrasonic tracking of shear waves using a particle filter.

PubMed

Ingle, Atul N; Ma, Chi; Varghese, Tomy

2015-11-01

This paper discusses an application of particle filtering for estimating shear wave velocity in tissue using ultrasound elastography data. Shear wave velocity estimates are of significant clinical value as they help differentiate stiffer areas from softer areas which is an indicator of potential pathology. Radio-frequency ultrasound echo signals are used for tracking axial displacements and obtaining the time-to-peak displacement at different lateral locations. These time-to-peak data are usually very noisy and cannot be used directly for computing velocity. In this paper, the denoising problem is tackled using a hidden Markov model with the hidden states being the unknown (noiseless) time-to-peak values. A particle filter is then used for smoothing out the time-to-peak curve to obtain a fit that is optimal in a minimum mean squared error sense. Simulation results from synthetic data and finite element modeling suggest that the particle filter provides lower mean squared reconstruction error with smaller variance as compared to standard filtering methods, while preserving sharp boundary detail. Results from phantom experiments show that the shear wave velocity estimates in the stiff regions of the phantoms were within 20% of those obtained from a commercial ultrasound scanner and agree with estimates obtained using a standard method using least-squares fit. Estimates of area obtained from the particle filtered shear wave velocity maps were within 10% of those obtained from B-mode ultrasound images. The particle filtering approach can be used for producing visually appealing SWV reconstructions by effectively delineating various areas of the phantom with good image quality properties comparable to existing techniques.

Non-stationary blind deconvolution of medical ultrasound scans

NASA Astrophysics Data System (ADS)

Michailovich, Oleg V.

2017-03-01

In linear approximation, the formation of a radio-frequency (RF) ultrasound image can be described based on a standard convolution model in which the image is obtained as a result of convolution of the point spread function (PSF) of the ultrasound scanner in use with a tissue reflectivity function (TRF). Due to the band-limited nature of the PSF, the RF images can only be acquired at a finite spatial resolution, which is often insufficient for proper representation of the diagnostic information contained in the TRF. One particular way to alleviate this problem is by means of image deconvolution, which is usually performed in a "blind" mode, when both PSF and TRF are estimated at the same time. Despite its proven effectiveness, blind deconvolution (BD) still suffers from a number of drawbacks, chief among which stems from its dependence on a stationary convolution model, which is incapable of accounting for the spatial variability of the PSF. As a result, virtually all existing BD algorithms are applied to localized segments of RF images. In this work, we introduce a novel method for non-stationary BD, which is capable of recovering the TRF concurrently with the spatially variable PSF. Particularly, our approach is based on semigroup theory which allows one to describe the effect of such a PSF in terms of the action of a properly defined linear semigroup. The approach leads to a tractable optimization problem, which can be solved using standard numerical methods. The effectiveness of the proposed solution is supported by experiments with in vivo ultrasound data.

Two-tone suppression in the cricket, Eunemobius carolinus (Gryllidae, Nemobiinae)

NASA Astrophysics Data System (ADS)

Farris, Hamilton E.; Hoy, Ronald R.

2002-03-01

Sounds with frequencies >15 kHz elicit an acoustic startle response (ASR) in flying crickets (Eunemobius carolinus). Although frequencies <15 kHz do not elicit the ASR when presented alone, when presented with ultrasound (40 kHz), low-frequency stimuli suppress the ultrasound-induced startle. Thus, using methods similar to those in masking experiments, we used two-tone suppression to assay sensitivity to frequencies in the audio band. Startle suppression was tuned to frequencies near 5 kHz, the frequency range of male calling songs. Similar to equal loudness contours measured in humans, however, equal suppression contours were not parallel, as the equivalent rectangular bandwidth of suppression tuning changed with increases in ultrasound intensity. Temporal integration of suppressor stimuli was measured using nonsimultaneous presentations of 5-ms pulses of 6 and 40 kHz. We found that no suppression occurs when the suppressing tone is >2 ms after and >5 ms before the ultrasound stimulus, suggesting that stimulus overlap is a requirement for suppression. When considered together with our finding that the intensity of low-frequency stimuli required for suppression is greater than that produced by singing males, the overlap requirement suggests that two-tone suppression functions to limit the ASR to sounds containing only ultrasound and not to broadband sounds that span the audio and ultrasound range.

Biophysical characterization of low-frequency ultrasound interaction with dental pulp stem cells

PubMed Central

2013-01-01

Background Low-intensity ultrasound is considered an effective non-invasive therapy to stimulate hard tissue repair, in particular to accelerate delayed non-union bone fracture healing. More recently, ultrasound has been proposed as a therapeutic tool to repair and regenerate dental tissues. Our recent work suggested that low-frequency kilohertz-range ultrasound is able to interact with dental pulp cells which could have potential to stimulate dentine reparative processes and hence promote the viability and longevity of teeth. Methods In this study, the biophysical characteristics of low-frequency ultrasound transmission through teeth towards the dental pulp were explored. We conducted cell culture studies using an odontoblast-like/dental pulp cell line, MDPC-23. Half of the samples underwent ultrasound exposure while the other half underwent ‘sham treatment’ where the transducer was submerged into the medium but no ultrasound was generated. Ultrasound was applied directly to the cell cultures using a therapeutic ultrasound device at a frequency of 45 kHz with intensity settings of 10, 25 and 75 mW/cm2 for 5 min. Following ultrasound treatment, the odontoblast-like cells were detached from the culture using a 0.25% Trypsin/EDTA solution, and viable cell numbers were counted. Two-dimensional tooth models based on μ-CT 2D images of the teeth were analyzed using COMSOL as the finite element analysis platform. This was used to confirm experimental results and to demonstrate the potential theory that with the correct combination of frequency and intensity, a tooth can be repaired using small doses of ultrasound. Frequencies in the 30 kHz–1 MHz range were analyzed. For each frequency, pressure/intensity plots provided information on how the intensity changes at each point throughout the propagation path. Spatial peak temporal average (SPTA) intensity was calculated and related to existing optimal spatial average temporal average (SATA) intensity deemed effective for cell proliferation during tooth repair. Results The results demonstrate that odontoblast MDPC-23 cell numbers were significantly increased following three consecutive ultrasound treatments over a 7-day culture period as compared with sham controls underscoring the anabolic effects of ultrasound on these cells. Data show a distinct increase in cell number compared to the sham data after ultrasound treatment for intensities of 10 and 25 mW/cm2 (p < 0.05 and p < 0.01, respectively). Using finite element analysis, we demonstrated that ultrasound does indeed propagate through the mineralized layers of the teeth and into the pulp chamber where it forms a ‘therapeutic’ force field to interact with the living dental pulp cells. This allowed us to observe the pressure/intensity of the wave as it propagates throughout the tooth. A selection of time-dependent snapshots of the pressure/intensity reveal that the lower frequency waves propagate to the pulp and remain within the chamber for a while, which is ideal for cell excitation. Input frequencies and pressures of 30 kHz (70 Pa) and 45 kHz (31 kPa), respectively, with an average SPTA of up to 120 mW/cm2 in the pulp seem to be optimal and agree with the SATA intensities reported experimentally. Conclusions Our data suggest that ultrasound can be harnessed to propagate to the dental pulp region where it can interact with the living cells to promote dentine repair. Further research is required to analyze the precise physical and biological interactions of low-frequency ultrasound with the dental pulp to develop a novel non-invasive tool for dental tissue regeneration. PMID:25516801

Absolute backscatter coefficient estimates of tissue-mimicking phantoms in the 5–50 MHz frequency range

PubMed Central

McCormick, Matthew M.; Madsen, Ernest L.; Deaner, Meagan E.; Varghese, Tomy

2011-01-01

Absolute backscatter coefficients in tissue-mimicking phantoms were experimentally determined in the 5–50 MHz frequency range using a broadband technique. A focused broadband transducer from a commercial research system, the VisualSonics Vevo 770, was used with two tissue-mimicking phantoms. The phantoms differed regarding the thin layers covering their surfaces to prevent desiccation and regarding glass bead concentrations and diameter distributions. Ultrasound scanning of these phantoms was performed through the thin layer. To avoid signal saturation, the power spectra obtained from the backscattered radio frequency signals were calibrated by using the signal from a liquid planar reflector, a water-brominated hydrocarbon interface with acoustic impedance close to that of water. Experimental values of absolute backscatter coefficients were compared with those predicted by the Faran scattering model over the frequency range 5–50 MHz. The mean percent difference and standard deviation was 54% ± 45% for the phantom with a mean glass bead diameter of 5.40 μm and was 47% ± 28% for the phantom with 5.16 μm mean diameter beads. PMID:21877789

Pulsed radio frequency energy in the treatment of complex diabetic foot wounds: two cases.

PubMed

Larsen, Jerrie A; Overstreet, Julia

2008-01-01

The use of radio waves (pulsed radio frequency energy) has become well accepted in the treatment of chronic wounds. We present 2 cases of complex diabetic foot wounds treated adjunctively with outpatient pulsed radio frequency energy using a solid-state, 27.12 MHz fixed power output radio frequency generator that transmits a fixed dose of nonionizing, nonthermal electromagnetic energy through an applicator pad. This therapy, in combination with offloading, debridement and advanced dressings, resulted in closure of both wounds in approximately 16 weeks.

Interference-free ultrasound imaging during HIFU therapy, using software tools

NASA Technical Reports Server (NTRS)

Vaezy, Shahram (Inventor); Held, Robert (Inventor); Sikdar, Siddhartha (Inventor); Managuli, Ravi (Inventor); Zderic, Vesna (Inventor)

2010-01-01

Disclosed herein is a method for obtaining a composite interference-free ultrasound image when non-imaging ultrasound waves would otherwise interfere with ultrasound imaging. A conventional ultrasound imaging system is used to collect frames of ultrasound image data in the presence of non-imaging ultrasound waves, such as high-intensity focused ultrasound (HIFU). The frames are directed to a processor that analyzes the frames to identify portions of the frame that are interference-free. Interference-free portions of a plurality of different ultrasound image frames are combined to generate a single composite interference-free ultrasound image that is displayed to a user. In this approach, a frequency of the non-imaging ultrasound waves is offset relative to a frequency of the ultrasound imaging waves, such that the interference introduced by the non-imaging ultrasound waves appears in a different portion of the frames.

MASER: A Tool Box for Solar System Low Frequency Radio Astronomy

NASA Astrophysics Data System (ADS)

Cecconi, B.; Le Sidaner, P.; Savalle, R.; Bonnin, X.; Zarka, P.; Louis, C.; Coffre, A.; Lamy, L.; Denis, L.; Griessmeier, J.-M.; Faden, J.; Piker, C.; André, N.; Génot, V.; Erard, S.; King, T. A.; Mafi, J. N.; Sharlow, M.; Sky, J.; Demleitner, M.

2018-04-01

MASER (Measuring, Analysing, and Simulating Radio Emissions) is a toolbox for solar system radio astronomy. It provides tools for reading, displaying, finding, and modeling low frequency radio datasets.

48 CFR 211.275 - Radio frequency identification.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Radio frequency identification. 211.275 Section 211.275 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS... Requirements Documents 211.275 Radio frequency identification. ...

Effects of low-frequency ultrasound on heterogenous deacetylation of chitin.

PubMed

Ngo, Thi Hoai Duong; Ngo, Dang Nghia

2017-11-01

The effects of low frequency ultrasound to the heterogeneous deacetylation of chitin from the shell of white shrimp (Penaeus vannamei) were examined. The deacetylation process was carried out in the range of NaOH concentrations from 35% to 65% (w/w) with and without the ultrasound in the frequency of 37kHz, RMS=300W. The chitosan obtained was characterized in the degree of deacetylation, solubility, FT-IR and X-ray diffraction. The results showed that the behaviors of the deacetylation in two cases, with and without ultrasound, were similar but the ultrasound enhanced the deacetylation rate and therefore reduced the time of the reaction to get the same degree of deacetylation. The role of ultrasound in the process showed more clearly in the low concentration of sodium hydroxide, below 45% (w/w). At the higher concentration of sodium hydroxide, the influence of ultrasound on facilitating deacetylation decreased significantly, however, ultrasound was still keeping on its improving effect on the solubility of the chitosan obtained. The data from FT-IR and X-ray diffraction did not show any considerable change in structure of both kinds of chitosan. This study showed the potential of using low frequency ultrasound in enhancing the deacetylation of chitin for reducing the chemical consumption. Copyright © 2017 Elsevier B.V. All rights reserved.

76 FR 67604 - Maritime Communications

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-02

... aviation and marine radio services use a marine very high frequency (VHF), medium frequency (MF), or high... aviation and marine radio services use a very high frequency (VHF) marine or aircraft radio and, as..., the Federal Communications Commission amends 47 CFR parts 2 and 80 as follows: PART 2--FREQUENCY...

Analysis of type II and type III solar radio bursts

NASA Astrophysics Data System (ADS)

Wijesekera, J. V.; Jayaratne, K. P. S. C.; Adassuriya, J.

2018-04-01

Solar radio burst is an arrangement of a frequency space that variation with time. Most of radio burst can be identified in low frequency range such as below 200 MHz and depending on frequencies. Solar radio bursts were the first phenomenon identified in the field of radio astronomy field. Solar radio frequency range is from 70 MHz to 2.2 GHz. Most of the radio burst can be identified in a low frequency range such as below 200 MHz. Properties of low-frequency radio were analyzed this research. There are two types of solar radio bursts were analyzed, named as type II and type III radio bursts. Exponential decay type could be seen in type II, and a linear could be indicated in type III solar radio bursts. The results of the drift rate graphs show the values of each chosen solar radio burst. High drift rate values can be seen in type III solar flares whereas low to medium drift rate values can be seen in type II solar flares. In the second part of the research the Newkirk model electron density model was used to estimate the drift velocities of the solar radio bursts. Although the special origin of the solar radio burst is not known clearly we assumed. The chosen solar radio bursts were originated within the solar radius of 0.9 - 1.3 range from the photosphere. We used power low in the form of (x) = A × 10‑bx were that the electron density related to the height of the solar atmosphere. The calculation of the plasma velocity of each solar radio burst was done using the electron density model and drift rates. Therefore velocity of chosen type II solar radio bursts indicates low velocities. The values are 233.2499 Km s‑1, 815.9522 Km s‑1 and 369.5425 Km s‑1. Velocity of chosen type III solar radio bursts were 1443.058 Km s‑1and 1205.05Km s ‑1.

The Frequency Spectrum Radio.

ERIC Educational Resources Information Center

Howkins, John, Ed.

1979-01-01

This journal issue focuses on the frequency spectrum used in radio communication and on the World Administrative Radio Conference, sponsored by the International Telecommunication Union, held in Geneva, Switzerland, in the fall of 1979. Articles describe the World Administrative Radio Conference as the most important radio communication conference…

Investigation on the Frequency Allocation for Radio Astronomy at the L Band

NASA Astrophysics Data System (ADS)

Abidin, Z. Z.; Umar, R.; Ibrahim, Z. A.; Rosli, Z.; Asanok, K.; Gasiprong, N.

2013-09-01

In this paper, the frequency allocation reserved for radio astronomy in the L band set by the International Telecommunication Union (ITU), which is between 1400 and 1427 MHz, is reviewed. We argue that the nearby frequencies are still very important for radio astronomers on the ground by investigating radio objects (H i sources) around 1300-1500 MHz. The L-band window is separated into a group of four windows, namely 1400-1427 MHz (window A), 1380-1400 MHz (window B), 1350-1380 MHz (window C), and 1300-1350 MHz (window D). These windows are selected according to their redshifts from a rest frequency for hydrogen spectral line at 1420.4057 MHz. Radio objects up to z ≈ 0.1 or frequency down to 1300 MHz are examined. We argue that since window B has important radio objects within the four windows, this window should also be given to radio astronomy. They are galaxies, spiral galaxies, and galaxy clusters. This underlines the significance of window B for radio astronomers on the ground. By investigating the severeness of radio frequency interference (RFI) within these windows, we have determined that window B still has significant, consistent RFI. The main RFI sources in the four windows have also been identified. We also found that the Department of Civil Aviation of Malaysia is assigned a frequency range of 1215-1427 MHz, which is transmitted within the four windows and inside the protected frequency for radio astronomy. We also investigated the RFI in the four windows on proposed sites of future radio astronomy observatories in Malaysia and Thailand and found the two best sites as Universiti Pendidikan Sultan Idris (UPSI) and Ubon Ratchathani, respectively. It has also been determined that RFI in window B increases with population density.

Unpowered wireless ultrasound tomography system

NASA Astrophysics Data System (ADS)

Zahedi, Farshad; Huang, Haiying

2016-04-01

In this paper, an unpowered wireless ultrasound tomography system is presented. The system consists of two subsystems; the wireless interrogation unit (WIU) and three wireless nodes installed on the structure. Each node is designed to work in generation and sensing modes, but operates at a specific microwave frequency. Wireless transmission of the ultrasound signals between the WIU and the wireless nodes is achieved by converting ultrasound signals to microwave signals and vice versa, using a microwave carrier signal. In the generation mode, both a carrier signal and an ultrasound modulated microwave signal are transmitted to the sensor nodes. Only the node whose operating frequency matches the carrier signal will receive these signals and demodulate them to recover the original ultrasound signal. In the sensing mode, a microwave carrier signal with two different frequency components matching the operating frequencies of the sensor nodes is broadcasted by the WIU. The sensor nodes, in turn, receive the corresponding carrier signals, modulate it with the ultrasound sensing signal, and wirelessly transmit the modulated signal back to the WIU. The demodulation of the sensing signals is performed in the WIU using a digital signal processing. Implementing a software receiver significantly reduces the complexity and the cost of the WIU. A wireless ultrasound tomography system is realized by interchanging the carrier frequencies so that the wireless transducers can take turn to serve as the actuator and sensors.

I. S. Shklovsky and Low-Frequency Radio Astronomy

NASA Astrophysics Data System (ADS)

Konovalenko, A. A.

2017-03-01

Purpose: Proving of the high astrophysical significance of the low-frequency radio astronomy (decameter and adjacent hectometer and meter wavelengths), demonstration of the priority results of the Ukrainian low-frequency radio astronomy as well as significant contribution of I. S. Shklovsky to its development. Design/methodology/approach: The requirements to characteristics of high efficiency radio telescopes UTR-2, URAN, GURT and to sensitive and interference immune observational methods at low frequencies are formulated by using the theoretical analysis and astrophysical predictions including those I. S. Shklovsky’s. Findings: New generation radio telescopes UTR-2, URAN, GURT are created and modernized. New observational methods at low frequencies are introduced. Large-scale investigations of the Solar system, Galaxy and Methagalaxy are carried out. They have allowed to detect new objects and phenomena for the continuum, monochromatic, pulse and sporadic cosmic radio emission. The role of I. S. Shklovsky in the development of many low-frequency radio astronomy directions is noted, too. Conclusions: The unique possibilities of the low-frequency radio astronomy which gives new information about the Universe, inaccessible with the other astrophysical methods, are shown. The progress of the low-frequency radio astronomy opens the impressive possibilities for the future. It includes modernization of the largest radio telescopes UTR-2, URAN, NDA and creation of new instruments GURT, NenuFAR, LOFAR, LWA, MWA, SKA as well as making multi-antenna and ground-space experiments. The contribution of outstanding astrophysicist of the XX century I. S. Shklovsky to this part of actual astronomical science is evident, claiming for attention and will never be forgotten.

48 CFR 211.275 - Passive radio frequency identification.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Passive radio frequency identification. 211.275 Section 211.275 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS... Requirements Documents 211.275 Passive radio frequency identification. ...

Particle beam injector system and method

DOEpatents

Guethlein, Gary

2013-06-18

Methods and devices enable coupling of a charged particle beam to a radio frequency quadrupole accelerator. Coupling of the charged particle beam is accomplished, at least in-part, by relying on of sensitivity of the input phase space acceptance of the radio frequency quadrupole to the angle of the input charged particle beam. A first electric field across a beam deflector deflects the particle beam at an angle that is beyond the acceptance angle of the radio frequency quadrupole. By momentarily reversing or reducing the established electric field, a narrow portion of the charged particle beam is deflected at an angle within the acceptance angle of the radio frequency quadrupole. In another configuration, beam is directed at an angle within the acceptance angle of the radio frequency quadrupole by the first electric field and is deflected beyond the acceptance angle of the radio frequency quadrupole due to the second electric field.

CONTROL AND FAULT DETECTOR CIRCUIT

DOEpatents

Winningstad, C.N.

1958-04-01

A power control and fault detectcr circuit for a radiofrequency system is described. The operation of the circuit controls the power output of a radio- frequency power supply to automatically start the flow of energizing power to the radio-frequency power supply and to gradually increase the power to a predetermined level which is below the point where destruction occurs upon the happening of a fault. If the radio-frequency power supply output fails to increase during such period, the control does not further increase the power. On the other hand, if the output of the radio-frequency power supply properly increases, then the control continues to increase the power to a maximum value. After the maximumn value of radio-frequency output has been achieved. the control is responsive to a ''fault,'' such as a short circuit in the radio-frequency system being driven, so that the flow of power is interrupted for an interval before the cycle is repeated.

High spectral purity Kerr frequency comb radio frequency photonic oscillator

PubMed Central

Liang, W.; Eliyahu, D.; Ilchenko, V. S.; Savchenkov, A. A.; Matsko, A. B.; Seidel, D.; Maleki, L.

2015-01-01

Femtosecond laser-based generation of radio frequency signals has produced astonishing improvements in achievable spectral purity, one of the basic features characterizing the performance of an radio frequency oscillator. Kerr frequency combs hold promise for transforming these lab-scale oscillators to chip-scale level. In this work we demonstrate a miniature 10 GHz radio frequency photonic oscillator characterized with phase noise better than −60 dBc Hz−1 at 10 Hz, −90 dBc Hz−1 at 100 Hz and −170 dBc Hz−1 at 10 MHz. The frequency stability of this device, as represented by Allan deviation measurements, is at the level of 10−10 at 1–100 s integration time—orders of magnitude better than existing radio frequency photonic devices of similar size, weight and power consumption. PMID:26260955

Multiple-frequency continuous wave ultrasonic system for accurate distance measurement

NASA Astrophysics Data System (ADS)

Huang, C. F.; Young, M. S.; Li, Y. C.

1999-02-01

A highly accurate multiple-frequency continuous wave ultrasonic range-measuring system for use in air is described. The proposed system uses a method heretofore applied to radio frequency distance measurement but not to air-based ultrasonic systems. The method presented here is based upon the comparative phase shifts generated by three continuous ultrasonic waves of different but closely spaced frequencies. In the test embodiment to confirm concept feasibility, two low cost 40 kHz ultrasonic transducers are set face to face and used to transmit and receive ultrasound. Individual frequencies are transmitted serially, each generating its own phase shift. For any given frequency, the transmitter/receiver distance modulates the phase shift between the transmitted and received signals. Comparison of the phase shifts allows a highly accurate evaluation of target distance. A single-chip microcomputer-based multiple-frequency continuous wave generator and phase detector was designed to record and compute the phase shift information and the resulting distance, which is then sent to either a LCD or a PC. The PC is necessary only for calibration of the system, which can be run independently after calibration. Experiments were conducted to test the performance of the whole system. Experimentally, ranging accuracy was found to be within ±0.05 mm, with a range of over 1.5 m. The main advantages of this ultrasonic range measurement system are high resolution, low cost, narrow bandwidth requirements, and ease of implementation.

SITE TECHNOLOGY CAPSULE: IITRI RADIO FREQUENCY HEATING TECHNOLOGY

EPA Science Inventory

Radio frequency heating (RFH) technologies use electromagnetic energy in the radio frequency i(RF) band to heat soil in-situ, thereby potentially enhancing the performances of standard soil vapor extraction (SVE) technologies. ontaminants are removed from in situ soils and transf...

SITE TECHNOLOGY CAPSULE: IITRI RADIO FREQUENCY HEATING TECHNOLOGY

EPA Science Inventory

Radio frequency heating (RFH) technologies use electromagnetic energy in the radio frequency (RF) band to heat soil in situ, thereby potentially enhancing the performance of standard soil vapor extraction (SVE) technologies. Contaminants are removed from in situ soils and transfe...

Low-Frequency Ultrasound Debridement in Chronic Wound Healing: A Systematic Review of Current Evidence

PubMed Central

Chang, Ying-Ju Ruby; Perry, Julie

2017-01-01

Chronic wounds are painful and debilitating to patients, pose a clinical challenge to physicians, and impose financial burden on the health-care system. New treatment options are therefore highly sought after. Ultrasound debridement is a promising technology that functions to disperse bacterial biofilms and stimulate wound healing. In this review, we focus on low-frequency ultrasound (20-60 kHz) and summarize the findings of 25 recent studies examining ultrasound efficacy. Ultrasound debridement appears to be most effective when used 3 times a week and has the potential to decrease exudate and slough, decrease patient pain, disperse biofilms, and increase healing in wounds of various etiology. Although current studies are generally of smaller size, the results are promising and we recommend the testing of low-frequency ultrasound therapy in clinical practice on a larger scale. PMID:29026808

Airborne non-contact and contact broadband ultrasounds for frequency attenuation profile estimation of cementitious materials.

PubMed

Gosálbez, J; Wright, W M D; Jiang, W; Carrión, A; Genovés, V; Bosch, I

2018-08-01

In this paper, the study of frequency-dependent ultrasonic attenuation in strongly heterogeneous cementitious materials is addressed. To accurately determine the attenuation over a wide frequency range, it is necessary to have suitable excitation techniques. We have analysed two kinds of ultrasound techniques: contact ultrasound and airborne non-contact ultrasound. The mathematical formulation for frequency-dependent attenuation has been established and it has been revealed that each technique may achieve similar results but requires specific different calibration processes. In particular, the airborne non-contact technique suffers high attenuation due to energy losses at the air-material interfaces. Thus, its bandwidth is limited to low frequencies but it does not require physical contact between transducer and specimen. In contrast, the classical contact technique can manage higher frequencies but the measurement depends on the pressure between the transducer and the specimen. Cement specimens have been tested with both techniques and frequency attenuation dependence has been estimated. Similar results were achieved at overlapping bandwidth and it has been demonstrated that the airborne non-contact ultrasound technique could be a viable alternative to the classical contact technique. Copyright © 2018 Elsevier B.V. All rights reserved.

On High and Low Starting Frequencies of Type II Radio Bursts

NASA Astrophysics Data System (ADS)

Sharma, J.; Mittal, N.

2017-06-01

We have studied the characteristics of type II radio burst during the period May 1996 to March 2015, for the solar cycle 23 and 24, observed by WIND/WAVES radio instrument. A total of 642 events were recorded by the instrument during the study period. We have divided the events with two starting frequency range (high > 1 MHz; low ≤ 1MHz) as type II1 (i.e., 1-16 MHz) radio burst and type II2 (i.e., 20 KHz - 1020 KHz) radio burst which constitute the DH and km type II radio burst observed by WIND spacecraft, and determined their time and frequency characteristics. The mean drift rate of type II1 and type II2 radio bursts is 29.76 × 10-4 MHz/s and 0.17 × 10-4 MHz/s respectively, which shows that type II1 with high start frequency hase larger drift rate than the type II2 with low starting frequencies. We have also reported that the start frequency and the drift rate of type II1 are in good correlation, with a linear correlation coefficient of 0.58.

High-frequency ultrasound-responsive block copolymer micelle.

PubMed

Wang, Jie; Pelletier, Maxime; Zhang, Hongji; Xia, Hesheng; Zhao, Yue

2009-11-17

Micelles of a diblock copolymer composed of poly(ethylene oxide) and poly(2-tetrahydropyranyl methacrylate) (PEO-b-PTHPMA) in aqueous solution could be disrupted by high-frequency ultrasound (1.1 MHz). It was found that, upon exposure to a high-intensity focused ultrasound (HIFU) beam at room temperature, the pH value of the micellar solution decreased over irradiation time. The infrared spectroscopic analysis of solid block copolymer samples collected from the ultrasound irradiated micellar solution revealed the formation of carboxylic acid dimers and hydroxyl groups. These characterization results suggest that the high-frequency HIFU beam could induce the hydrolysis reaction of THPMA at room temperature resulting in the cleavage of THP groups. The disruption of PEO-b-PTHPMA micelles by ultrasound was investigated by using dynamic light scattering, atomic force microscopy, and fluorescence spectroscopy. On the basis of the pH change, it was found that the disruption process was determined by a number of factors such as the ultrasound power, the micellar solution volume and the location of the focal spot of the ultrasound beam. This study shows the potential to develop ultrasound-sensitive block copolymer micelles by having labile chemical bonds in the polymer structure, and to use the high-frequency HIFU to trigger a chemical reaction for the disruption of micelles.

[Evolution of nodular scleritis with ultrasound biomicroscopy: case report].

PubMed

Martinez, Andrea Alejandra Gonzalez; Matos, Kimble Teixeira Fonseca; Trevisani, Virgínia; Hirai, Alcides; Allemann, Norma

2013-01-01

To establish evolutionary pattern of a case of nodular scleritis with high frequency ultrasound during treatment. Twenty-seven year old female, initial manifestation of intermediate uveitis, bilateral macular edema after clinical treatment with topical and oral steroids. After four months, we observed the formation of a scleral nodule in the right eye when patient underwent high frequency ultrasound (Paradigm, 50 MHz transducer, immersion technique). The lesion in right eye was characterized at high frequency ultrasound as a nodular lesion located at the anterior inferior temporal wall associated with localized reduction of scleral thickness. After intravitreal injection of triamcinolone for treatment of macular edema, clinical regression of the scleral nodule was observed in right eye, maintaining reduced scleral thickness. High frequency ultrasound assisted in the diagnosis of nodular scleritis during the phases of treatment and in the identify its characteristic sequel feature, the scleral thinning.

DEMONSTRATION BULLETIN: RADIO FREQUENCY HEATING - KAI TECHNOLOGIES, INC.

EPA Science Inventory

Radio frequency heating (RFH) is a process that uses electromagnetic energy in the radio frequency (RF) band to heat soil in situ, thereby potentially enhancing the performance of standard soil vapor extraction (SVE) technologies. An RFH system developed by KAI Technologies, I...

IN SITU AND SOIL DECONTAMINATION BY RADIO FREQUENCY HEATING

EPA Science Inventory

In situ radio frequency heating is performed by applying electromagnetic energy in the radio frequency band to an array of electrodes placed in bore holes drilled through the contaminated soil. he process removes organic contaminants from large volumes of soil by volatilization, ...

High-power radio-frequency attenuation device

DOEpatents

Kerns, Q.A.; Miller, H.W.

1981-12-30

A resistor device for attenuating radio frequency power includes a radio frequency conductor connected to a series of fins formed of high relative magnetic permeability material. The fins are dimensional to accommodate the skin depth of the current conduction therethrough, as well as an inner heat conducting portion where current does not travel. Thermal connections for air or water cooling are provided for the inner heat conducting portions of each fin. Also disclosed is a resistor device to selectively alternate unwanted radio frequency energy in a resonant cavity.

Marine asset security and tracking (MAST) system

DOEpatents

Hanson, Gregory Richard [Clinton, TN; Smith, Stephen Fulton [Loudon, TN; Moore, Michael Roy [Corryton, TN; Dobson, Eric Lesley [Charleston, SC; Blair, Jeffrey Scott [Charleston, SC; Duncan, Christopher Allen [Marietta, GA; Lenarduzzi, Roberto [Knoxville, TN

2008-07-01

Methods and apparatus are described for marine asset security and tracking (MAST). A method includes transmitting identification data, location data and environmental state sensor data from a radio frequency tag. An apparatus includes a radio frequency tag that transmits identification data, location data and environmental state sensor data. Another method includes transmitting identification data and location data from a radio frequency tag using hybrid spread-spectrum modulation. Another apparatus includes a radio frequency tag that transmits both identification data and location data using hybrid spread-spectrum modulation.

High power radio frequency attenuation device

DOEpatents

Kerns, Quentin A.; Miller, Harold W.

1984-01-01

A resistor device for attenuating radio frequency power includes a radio frequency conductor connected to a series of fins formed of high relative magnetic permeability material. The fins are dimensional to accommodate the skin depth of the current conduction therethrough, as well as an inner heat conducting portion where current does not travel. Thermal connections for air or water cooling are provided for the inner heat conducting portions of each fin. Also disclosed is a resistor device to selectively alternate unwanted radio frequency energy in a resonant cavity.

NASA Radio Frequency Spectrum Management Manual

NASA Technical Reports Server (NTRS)

1989-01-01

The Radio Frequency (RF) Spectrum Management Manual sets forth procedures and guidelines for the management requirements for controlling the use of radio frequencies by the National Aeronautics and Space Administration. It is applicable to NASA Headquarters and field installations. NASA Management Instruction 1102.3 assigns the authority for management of radio frequencies for the National Aeronautics and Space Administration to the Associate Administrator for Space Operations, NASA Headquarters. This manual is issued in loose-leaf form and will be revised by page changes.

Using Solar Radio Burst Integrated Fluxes to Predict Energetic Proton Flux Increases.

DTIC Science & Technology

1982-08-31

Energy Density, ET, of the radio burst, an integration across the frequency interval of the time-integrated radio fluxes at each frequency, was found to...integrated flux or energy at five frequencies in the 600- to 8800-MHz frequency interval and related them to the peak proton flux of the associated... energy of the burst normalized to its peak flux. One other characteristic of the radio burst to which Croom 13 referred was the total energy density, ET

Radio frequency spectrum management

NASA Astrophysics Data System (ADS)

Sujdak, E. J., Jr.

1980-03-01

This thesis is a study of radio frequency spectrum management as practiced by agencies and departments of the Federal Government. After a brief introduction to the international agency involved in radio frequency spectrum management, the author concentrates on Federal agencies engaged in frequency management. These agencies include the National Telecommunications and Information Administration (NTIA), the Interdepartment Radio Advisory Committee (IRAC), and the Department of Defense (DoD). Based on an analysis of Department of Defense frequency assignment procedures, recommendations are given concerning decentralizing military frequency assignment by delegating broader authority to unified commanders. This proposal includes a recommendation to colocate the individual Service frequency management offices at the Washington level. This would result in reduced travel costs, lower manpower requirements, and a common tri-Service frequency management data base.

Method of reduction of the number of driving system channels for phased-array transducers using isolation transformers.

PubMed

Fjield, T; Hynynen, K

2000-01-01

Phased-array technology offers an incredible advantage to therapeutic ultrasound due to the ability to electronically steer foci, create multiple foci, or to create an enlarged focal region by using phase cancellation. However, to take advantage of this flexibility, the phased-arrays generally consist of many elements. Each of these elements requires its own radio-frequency generator with independent amplitude and phase control, resulting in a large, complex, and expensive driving system. A method is presented here where in certain cases the number of amplifier channels can be reduced to a fraction of the number of transducer elements, thereby simplifying the driving system and reducing the overall system complexity and cost, by using isolation transformers to produce 180 degrees phase shifts.

Dependence of thresholds for pulmonary capillary hemorrhage on diagnostic ultrasound frequency.

PubMed

Miller, Douglas L; Dou, Chunyan; Raghavendran, Krishnan

2015-06-01

Pulmonary ultrasound examination has become routine for diagnosis in many clinical and point-of-care medical settings. However, the phenomenon of pulmonary capillary hemorrhage (PCH) induction during diagnostic ultrasound imaging presents a poorly understood risk factor. PCH was observed in anesthetized rats exposed to 1.5-, 4.5- and 12.0-MHz diagnostic ultrasound to investigate the frequency dependence of PCH thresholds. PCH was detected in the ultrasound images as growing comet tail artifacts and was assessed using photographs of the surface of excised lungs. Previous photographs acquired after exposure to 7.6-MHz diagnostic ultrasound were included for analysis. In addition, at each frequency we measured dosimetric parameters, including peak rarefactional pressure amplitude and spatial peak, pulse average intensity attenuated by rat chest wall samples. Peak rarefactional pressure amplitude thresholds determined at each frequency, based on the proportion of PCH in groups of five rats, were 1.03 ± 0.02, 1.28 ± 0.14, 1.18 ± 0.12 and 1.36 ± 0.15 MPa at 1.5, 4.5, 7.6 and 12.0 MHz, respectively. Although the PCH lesions decreased in size with increasing ultrasonic frequency, owing to the smaller beam widths and scan lengths, the peak rarefactional pressure amplitude thresholds remained approximately constant. This dependence was different from that of the mechanical index, which indicates a need for a specific dosimetric parameter for safety guidance in pulmonary ultrasound. Copyright © 2015 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

Effects of radio frequency identification-related radiation on in vitro biologics.

PubMed

Uysal, Ismail; Hohberger, Clive; Rasmussen, R Scott; Ulrich, David A; Emond, Jean-Pierre; Gutierrez, Alfonso

2012-01-01

The recent developments on the use of e-pedigree to identify the chain of custody of drugs suggests the use of advanced track and trace technologies such as two-dimensional barcodes and radio frequency identification (RFID) tags. RFID technology is used mainly for valuable commodities such as pharmaceutical products while incorporating additional functionalities like monitoring environmental variables to ensure product safety and quality. In its guidance for the use of RFID technologies for drugs (Compliance Policy Guide Section 400.210), the Food and Drug Administration outlined multiple parameters that would apply to any study or application using RFID. However, drugs approved under a Biologics License Application or protein drugs covered by a New Drug Application were excluded mainly due to concerns about the effects of radio frequency radiation (thermal and/or non-thermal) on biologics. Even though the thermal effects of radio frequency on biologics are relatively well understood, there are few studies in the literature about the non-thermal effects of radio frequency with regards to the protein structure integrity. In this paper, we analyze the non-thermal effects of radio frequency radiation by exposing a wide variety of biologics including biopharmaceuticals with vaccines, hormones, and immunoglobulins, as well as cellular blood products such as red blood cells and whole blood-derived platelets as well as fresh frozen plasma. In order to represent the majority of the frequency spectrum used in RFID applications, five different frequencies (13.56 MHz, 433 MHz, 868 MHz, 915 MHz, and 2.4 GHz) are used to account for the most commonly used international frequency bands for RFID. With the help of specialized radio frequency signal-generating hardware, magnetic and electromagnetic fields are created around the exposed products with power levels greater than Federal Communications Commission-regulated limits. The in vitro test results on more than 100 biopharmaceutical products from eight major pharmaceutical companies as well, as different blood products, show no non-thermal effect by radio frequency radiation. Forthcoming requirements, such as the California Board of Pharmacy Track and Trace initiative regarding the use of e-pedigree to identify the chain of custody of drugs, suggest the use of advanced track and trace technologies such as two-dimensional barcodes and radio frequency identification (RFID) tags. When used for pharmaceuticals, RFID technology can support additional functionalities like monitoring temperature to ensure product safety. In its guidance for the use of RFID technologies for drugs, the Food and Drug Administration outlined multiple parameters that would apply to pilot studies using RFID while excluding drugs approved under a Biologics License Application or protein drugs covered by a New Drug Application due to concerns about the effects of radio frequency radiation on biologics. Even though the effects of radio frequency on biologics due to temperature changes are relatively well understood, there are few studies in the literature about other effects of radio frequency that can occur without a noticeable change in temperature. In this paper, we expose a wide variety of biologics including biopharmaceuticals to radio frequency radiation at different frequencies, as well as cellular blood products and plasma to high frequency radiation. The in vitro test results show no detectable effect due to radio frequency radiation.

Noncontact modal analysis of a pipe organ reed using airborne ultrasound stimulated vibrometry

NASA Astrophysics Data System (ADS)

Huber, Thomas M.; Fatemi, Mostafa; Kinnick, Randall R.; Greenleaf, James F.

2004-05-01

The goal of this experiment was to excite and measure, in a noncontact manner, the vibrational modes of the reed from a reed organ pipe. To perform ultrasound stimulated excitation, two ultrasound beams in air of different frequencies were directed at the reed; the audio-range beat frequency between these ultrasound beams induced vibrations. The resulting vibrational deflection shapes were measured with a scanning vibrometer. The modes of any relatively small object can be studied in air using this technique. For a 36 mm by 7 mm clamped brass reed cantilever, displacements and velocites of 5 μ and 4 mm/s could be imparted at the fundamental frequency of 145 Hz. Using the same ultrasound transducer, excitation across the entire range of audio frequencies was obtained, which was not possible using audio excitation with a speaker. Since the beam was focused on the reed, ultrasound stimulated excitation eliminated background effects observed during mechanical shaker excitation, such as vibrations of clamps and supports. We will discuss the results obtained using single, dual, and confocal ultrasound transducers in AM and unmodulated CW modes, along with results obtained using a mechanical shaker and audio excitation using a speaker.

High frequency ultrasound: a new frontier for ultrasound.

PubMed

Shung, K; Cannata, Jonathan; Qifa Zhou, Member; Lee, Jungwoo

2009-01-01

High frequency ultrasonic imaging is considered by many to be the next frontier in ultrasonic imaging because higher frequencies yield much improved spatial resolution by sacrificing the depth of penetration. It has many clinical applications including visualizing blood vessel wall, anterior segments of the eye and skin. Another application is small animal imaging. Ultrasound is especially attractive in imaging the heart of a small animal like mouse which has a size in the mm range and a heart beat rate faster than 600 BPM. A majority of current commercial high frequency scanners often termed "ultrasonic backscatter microscope or UBM" acquire images by scanning single element transducers at frequencies between 50 to 80 MHz with a frame rate lower than 40 frames/s, making them less suitable for this application. High frequency linear arrays and linear array based ultrasonic imaging systems at frequencies higher than 30 MHz are being developed. The engineering of such arrays and development of high frequency imaging systems has been proven to be highly challenging. High frequency ultrasound may find other significant biomedical applications. The development of acoustic tweezers for manipulating microparticles is such an example.

Method and apparatus for radio frequency ceramic sintering

DOEpatents

Hoffman, Daniel J.; Kimrey, Jr., Harold D.

1993-01-01

Radio frequency energy is used to sinter ceramic materials. A coaxial waveguide resonator produces a TEM mode wave which generates a high field capacitive region in which a sample of the ceramic material is located. Frequency of the power source is kept in the range of radio frequency, and preferably between 60-80 MHz. An alternative embodiment provides a tunable radio frequency circuit which includes a series input capacitor and a parallel capacitor, with the sintered ceramic connected by an inductive lead. This arrangement permits matching of impedance over a wide range of dielectric constants, ceramic volumes, and loss tangents.

Method and apparatus for radio frequency ceramic sintering

DOEpatents

Hoffman, D.J.; Kimrey, H.D. Jr.

1993-11-30

Radio frequency energy is used to sinter ceramic materials. A coaxial waveguide resonator produces a TEM mode wave which generates a high field capacitive region in which a sample of the ceramic material is located. Frequency of the power source is kept in the range of radio frequency, and preferably between 60-80 MHz. An alternative embodiment provides a tunable radio frequency circuit which includes a series input capacitor and a parallel capacitor, with the sintered ceramic connected by an inductive lead. This arrangement permits matching of impedance over a wide range of dielectric constants, ceramic volumes, and loss tangents. 6 figures.

47 CFR 80.927 - Antenna radio frequency indicator.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 5 2014-10-01 2014-10-01 false Antenna radio frequency indicator. 80.927... Boats § 80.927 Antenna radio frequency indicator. The transmitter must be equipped with a device which provides visual indication whenever the transmitter is supplying power to the antenna. ...

47 CFR 80.927 - Antenna radio frequency indicator.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 5 2010-10-01 2010-10-01 false Antenna radio frequency indicator. 80.927... Boats § 80.927 Antenna radio frequency indicator. The transmitter must be equipped with a device which provides visual indication whenever the transmitter is supplying power to the antenna. ...

47 CFR 80.927 - Antenna radio frequency indicator.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 47 Telecommunication 5 2012-10-01 2012-10-01 false Antenna radio frequency indicator. 80.927... Boats § 80.927 Antenna radio frequency indicator. The transmitter must be equipped with a device which provides visual indication whenever the transmitter is supplying power to the antenna. ...

47 CFR 80.927 - Antenna radio frequency indicator.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 5 2013-10-01 2013-10-01 false Antenna radio frequency indicator. 80.927... Boats § 80.927 Antenna radio frequency indicator. The transmitter must be equipped with a device which provides visual indication whenever the transmitter is supplying power to the antenna. ...

47 CFR 80.927 - Antenna radio frequency indicator.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 5 2011-10-01 2011-10-01 false Antenna radio frequency indicator. 80.927... Boats § 80.927 Antenna radio frequency indicator. The transmitter must be equipped with a device which provides visual indication whenever the transmitter is supplying power to the antenna. ...

Reconfigurable radio-frequency arbitrary waveforms synthesized in a silicon photonic chip.

PubMed

Wang, Jian; Shen, Hao; Fan, Li; Wu, Rui; Niu, Ben; Varghese, Leo T; Xuan, Yi; Leaird, Daniel E; Wang, Xi; Gan, Fuwan; Weiner, Andrew M; Qi, Minghao

2015-01-12

Photonic methods of radio-frequency waveform generation and processing can provide performance advantages and flexibility over electronic methods due to the ultrawide bandwidth offered by the optical carriers. However, bulk optics implementations suffer from the lack of integration and slow reconfiguration speed. Here we propose an architecture of integrated photonic radio-frequency generation and processing and implement it on a silicon chip fabricated in a semiconductor manufacturing foundry. Our device can generate programmable radio-frequency bursts or continuous waveforms with only the light source, electrical drives/controls and detectors being off-chip. It modulates an individual pulse in a radio-frequency burst within 4 ns, achieving a reconfiguration speed three orders of magnitude faster than thermal tuning. The on-chip optical delay elements offer an integrated approach to accurately manipulating individual radio-frequency waveform features without constraints set by the speed and timing jitter of electronics, and should find applications ranging from high-speed wireless to defence electronics.

Reconfigurable radio-frequency arbitrary waveforms synthesized in a silicon photonic chip

PubMed Central

Wang, Jian; Shen, Hao; Fan, Li; Wu, Rui; Niu, Ben; Varghese, Leo T.; Xuan, Yi; Leaird, Daniel E.; Wang, Xi; Gan, Fuwan; Weiner, Andrew M.; Qi, Minghao

2015-01-01

Photonic methods of radio-frequency waveform generation and processing can provide performance advantages and flexibility over electronic methods due to the ultrawide bandwidth offered by the optical carriers. However, bulk optics implementations suffer from the lack of integration and slow reconfiguration speed. Here we propose an architecture of integrated photonic radio-frequency generation and processing and implement it on a silicon chip fabricated in a semiconductor manufacturing foundry. Our device can generate programmable radio-frequency bursts or continuous waveforms with only the light source, electrical drives/controls and detectors being off-chip. It modulates an individual pulse in a radio-frequency burst within 4 ns, achieving a reconfiguration speed three orders of magnitude faster than thermal tuning. The on-chip optical delay elements offer an integrated approach to accurately manipulating individual radio-frequency waveform features without constraints set by the speed and timing jitter of electronics, and should find applications ranging from high-speed wireless to defence electronics. PMID:25581847

Thrombolysis using multi-frequency high intensity focused ultrasound at MHz range: an in vitro study

NASA Astrophysics Data System (ADS)

Suo, Dingjie; Guo, Sijia; Lin, Weili; Jiang, Xiaoning; Jing, Yun

2015-09-01

High intensity focused ultrasound (HIFU) based thrombolysis has emerged as a promising drug-free treatment approach for ischemic stroke. The large amount of acoustic power required by this approach, however, poses a critical challenge to the future clinical translation. In this study, multi-frequency acoustic waves at MHz range (near 1.5 MHz) were introduced as HIFU excitations to reduce the required power for treatment as well as the treatment time. In vitro bovine blood clots weighing around 150 mg were treated by single-frequency and multi-frequency HIFU. The pulse length was 2 ms for all experiments except the ones where the duty cycle was changed. It was found that dual-frequency thrombolysis efficiency was statistically better than single-frequency under the same acoustic power and excitation condition. When varying the acoustic power but fixing the duty cycle at 5%, it was found that dual-frequency ultrasound can save almost 30% power in order to achieve the same thrombolysis efficiency. In the experiment where the duty cycle was increased from 0.5% to 10%, it was shown that dual-frequency ultrasound can achieve the same thrombolysis efficiency with only half of the duty cycle of single-frequency. Dual-frequency ultrasound could also accelerate the thrombolysis by a factor of 2-4 as demonstrated in this study. No significant differences were found between dual-frequencies with different frequency differences (0.025, 0.05, and 0.1 MHz) and between dual-frequency and triple-frequency. The measured cavitation doses of dual-frequency and triple-frequency excitations were at about the same level but both were significantly higher than that of single-frequency.

Manipulating neuronal activity with low frequency transcranial ultrasound

NASA Astrophysics Data System (ADS)

Moore, Michele Elizabeth

Stimulation of the rodent cerebral cortex is used to investigate the underlying biological basis for the restorative effects of slow wave sleep. Neuronal activation by optogenetic and ultrasound stimulation elicits changes in action potentials across the cerebral cortex that are recorded as electroencephalograms. Optogenetic stimulation requires an invasive implantation procedure limiting its application in human studies. We sought to determine whether ultrasound stimulation could be as effective as optogenetic techniques currently used, in an effort to further understand the physiological and metabolic requirements of sleep. We successfully recorded electroencephalograms in response to transcranial ultrasound stimulation of the barrel cortex at 1 and 7 Hz frequencies, comparing them to those recorded in response to optogenetic stimuli applied at the same frequencies. Our results showed application of a 473 nm blue LED positioned 6 cm above the skull and ultrasound stimulation at an output voltage of 1000 mVpp produced electroencephalograms with physiological responses of similar amplitude. We concluded that there exists an intensity-proportionate response in the optogenetic stimulation, but not with ultrasound stimulation at the frequencies we surveyed. Activation of neuronal cells in response to optogenetic stimulation in a Thy1-ChR2 transgenic mouse line is specifically targeted to pyramidal cells in the cerebral cortex. ChR2 responses to optogenetic stimulation are mediated by a focal activation of neuronal ion channels. We measured electrophysiological responses to ultrasound stimulation, comparing them to those recorded from optogenetic stimuli. Our results show striking similarities between ultrasound-induced responses and optogenetically-induced responses, which may indicate that transcranial ultrasound stimulation is also mediated by ion channel dependent processes in cerebral cortical neurons. The biophysical substrates for electrical excitability of neurons impose temporal constraints on their response to stimulation. If ultrasound-mediated responses are, in fact, ion channel mediated responses, ultrasound-induced responses should exhibit time-dependence characteristics similar to those of optogenetically-triggered responses. Minimal stimulus duration thresholds and the temporal limits of paired pulse facilitation for ultrasound stimulation were identical to those of optogenetic stimulation. Collectively, these experiments demonstrate an electrophysiological basis for low-frequency transcranial ultrasound stimulation of cerebral cortical neuronal activity.

Ultrasound

MedlinePlus

Ultrasound is a type of imaging. It uses high-frequency sound waves to look at organs and ... liver, and other organs. During pregnancy, doctors use ultrasound to view the fetus. Unlike x-rays, ultrasound ...

THE LOW-FREQUENCY RADIO CATALOG OF FLAT-SPECTRUM SOURCES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Massaro, F.; Giroletti, M.; D'Abrusco, R.

A well known property of the γ-ray sources detected by Cos-B in the 1970s, by the Compton Gamma-Ray Observatory in the 1990s, and recently by the Fermi observations is the presence of radio counterparts, particularly for those associated with extragalactic objects. This observational evidence is the basis of the radio-γ-ray connection established for the class of active galactic nuclei known as blazars. In particular, the main spectral property of the radio counterparts associated with γ-ray blazars is that they show a flat spectrum in the GHz frequency range. Our recent analysis dedicated to search blazar-like candidates as potential counterparts formore » the unidentified γ-ray sources allowed us to extend the radio-γ-ray connection in the MHz regime. We also showed that blazars below 1 GHz maintain flat radio spectra. Thus, on the basis of these new results, we assembled a low-frequency radio catalog of flat-spectrum sources built by combining the radio observations of the Westerbork Northern Sky Survey and of the Westerbork in the southern hemisphere catalog with those of the NRAO Very Large Array Sky survey (NVSS). This could be used in the future to search for new, unknown blazar-like counterparts of γ-ray sources. First, we found NVSS counterparts of Westerbork Synthesis Radio Telescope radio sources, and then we selected flat-spectrum radio sources according to a new spectral criterion, specifically defined for radio observations performed below 1 GHz. We also described the main properties of the catalog listing 28,358 radio sources and their logN-logS distributions. Finally, a comparison with the Green Bank 6 cm radio source catalog was performed to investigate the spectral shape of the low-frequency flat-spectrum radio sources at higher frequencies.« less

High pulse repetition frequency ultrasound system for ex vivo measurement of mechanical properties of crystalline lenses with laser-induced microbubble interrogated by acoustic radiation force

PubMed Central

Yoon, Sangpil; Aglyamov, Salavat; Karpiouk, Andrei; Emelianov, Stanislav

2012-01-01

A high pulse repetition frequency ultrasound system for ex vivo measurement of mechanical properties of animal crystalline lens was developed and validated. We measured the bulk displacement of laser-induced microbubbles created at different positions within the lens using nanosecond laser pulses. An impulsive acoustic radiation force was applied to the microbubble, and spatio-temporal measurements of the microbubble displacement were assessed using a custom-made high pulse repetition frequency ultrasound system consisting of two 25 MHz focused ultrasound transducers. One of these transducers was used to emit a train of ultrasound pulses and another transducer was used to receive the ultrasound echoes reflected from the microbubble. The developed system was operating at 1 MHz pulse repetition frequency. Based on measured motion of the microbubble, the Young’s moduli of surrounding tissue were reconstructed and the values were compared with those measured using indentation test. Measured values of Young’s moduli of 4 bovine lenses ranged from 2.6±0.1 to 26±1.4 kPa and there was good agreement between the two methods. Therefore, our studies, utilizing the high pulse repetition frequency ultrasound system, suggest that the developed approach can be used to assess the mechanical properties of ex vivo crystalline lenses. Furthermore, the potential of the presented approach for in vivo measurements is discussed. PMID:22797709

Extracting cardiac myofiber orientations from high frequency ultrasound images

NASA Astrophysics Data System (ADS)

Qin, Xulei; Cong, Zhibin; Jiang, Rong; Shen, Ming; Wagner, Mary B.; Kirshbom, Paul; Fei, Baowei

2013-03-01

Cardiac myofiber plays an important role in stress mechanism during heart beating periods. The orientation of myofibers decides the effects of the stress distribution and the whole heart deformation. It is important to image and quantitatively extract these orientations for understanding the cardiac physiological and pathological mechanism and for diagnosis of chronic diseases. Ultrasound has been wildly used in cardiac diagnosis because of its ability of performing dynamic and noninvasive imaging and because of its low cost. An extraction method is proposed to automatically detect the cardiac myofiber orientations from high frequency ultrasound images. First, heart walls containing myofibers are imaged by B-mode high frequency (<20 MHz) ultrasound imaging. Second, myofiber orientations are extracted from ultrasound images using the proposed method that combines a nonlinear anisotropic diffusion filter, Canny edge detector, Hough transform, and K-means clustering. This method is validated by the results of ultrasound data from phantoms and pig hearts.

A GPU-Accelerated 3-D Coupled Subsample Estimation Algorithm for Volumetric Breast Strain Elastography.

PubMed

Peng, Bo; Wang, Yuqi; Hall, Timothy J; Jiang, Jingfeng

2017-04-01

Our primary objective of this paper was to extend a previously published 2-D coupled subsample tracking algorithm for 3-D speckle tracking in the framework of ultrasound breast strain elastography. In order to overcome heavy computational cost, we investigated the use of a graphic processing unit (GPU) to accelerate the 3-D coupled subsample speckle tracking method. The performance of the proposed GPU implementation was tested using a tissue-mimicking phantom and in vivo breast ultrasound data. The performance of this 3-D subsample tracking algorithm was compared with the conventional 3-D quadratic subsample estimation algorithm. On the basis of these evaluations, we concluded that the GPU implementation of this 3-D subsample estimation algorithm can provide high-quality strain data (i.e., high correlation between the predeformation and the motion-compensated postdeformation radio frequency echo data and high contrast-to-noise ratio strain images), as compared with the conventional 3-D quadratic subsample algorithm. Using the GPU implementation of the 3-D speckle tracking algorithm, volumetric strain data can be achieved relatively fast (approximately 20 s per volume [2.5 cm ×2.5 cm ×2.5 cm]).

Stabilized radio-frequency quadrupole

DOEpatents

Lancaster, H.D.; Fugitt, J.A.; Howard, D.R.

1982-09-29

A long-vane stabilized radio frequency resonator for accelerating charged particles and including means defining a radio frequency resonator cavity, a plurality of long vanes mounted in the defining means for dividing the cavity into sections, and means interconnecting opposing ones of the plurality of vanes for stabilizing the resonator.

Stabilized radio frequency quadrupole

DOEpatents

Lancaster, Henry D.; Fugitt, Jock A.; Howard, Donald R.

1984-01-01

A long-vane stabilized radio frequency resonator for accelerating charged particles and including means defining a radio frequency resonator cavity, a plurality of long vanes mounted in the defining means for dividing the cavity into sections, and means interconnecting opposing ones of the plurality of vanes for stabilizing the resonator.

78 FR 19311 - Certain Radio Frequency Identification (“RFID”) Products And Components Thereof; Institution of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-29

... Identification (``RFID'') Products And Components Thereof; Institution of Investigation Pursuant to 19 U.S.C... sale within the United States after importation of certain radio frequency identification (``RFID... after importation of certain radio frequency identification (``RFID'') products and components thereof...

TU-A-9A-06: Semi-Automatic Segmentation of Skin Cancer in High-Frequency Ultrasound Images: Initial Comparison with Histology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gao, Y; Li, X; Fishman, K

Purpose: In skin-cancer radiotherapy, the assessment of skin lesion is challenging, particularly with important features such as the depth and width hard to determine. The aim of this study is to develop interative segmentation method to delineate tumor boundary using high-frequency ultrasound images and to correlate the segmentation results with the histopathological tumor dimensions. Methods: We analyzed 6 patients who comprised a total of 10 skin lesions involving the face, scalp, and hand. The patient’s various skin lesions were scanned using a high-frequency ultrasound system (Episcan, LONGPORT, INC., PA, U.S.A), with a 30-MHz single-element transducer. The lateral resolution was 14.6more » micron and the axial resolution was 3.85 micron for the ultrasound image. Semiautomatic image segmentation was performed to extract the cancer region, using a robust statistics driven active contour algorithm. The corresponding histology images were also obtained after tumor resection and served as the reference standards in this study. Results: Eight out of the 10 lesions are successfully segmented. The ultrasound tumor delineation correlates well with the histology assessment, in all the measurements such as depth, size, and shape. The depths measured by the ultrasound have an average of 9.3% difference comparing with that in the histology images. The remaining 2 cases suffered from the situation of mismatching between pathology and ultrasound images. Conclusion: High-frequency ultrasound is a noninvasive, accurate and easy-accessible modality to image skin cancer. Our segmentation method, combined with high-frequency ultrasound technology, provides a promising tool to estimate the extent of the tumor to guide the radiotherapy procedure and monitor treatment response.« less

Streaming flow from ultrasound contrast agents by acoustic waves in a blood vessel model.

PubMed

Cho, Eunjin; Chung, Sang Kug; Rhee, Kyehan

2015-09-01

To elucidate the effects of streaming flow on ultrasound contrast agent (UCA)-assisted drug delivery, streaming velocity fields from sonicated UCA microbubbles were measured using particle image velocimetry (PIV) in a blood vessel model. At the beginning of ultrasound sonication, the UCA bubbles formed clusters and translated in the direction of the ultrasound field. Bubble cluster formation and translation were faster with 2.25MHz sonication, a frequency close to the resonance frequency of the UCA. Translation of bubble clusters induced streaming jet flow that impinged on the vessel wall, forming symmetric vortices. The maximum streaming velocity was about 60mm/s at 2.25MHz and decreased to 15mm/s at 1.0MHz for the same acoustic pressure amplitude. The effect of the ultrasound frequency on wall shear stress was more noticeable. Maximum wall shear stress decreased from 0.84 to 0.1Pa as the ultrasound frequency decreased from 2.25 to 1.0MHz. The maximum spatial gradient of the wall shear stress also decreased from 1.0 to 0.1Pa/mm. This study showed that streaming flow was induced by bubble cluster formation and translation and was stronger upon sonication by an acoustic wave with a frequency near the UCA resonance frequency. Therefore, the secondary radiant force, which is much stronger at the resonance frequency, should play an important role in UCA-assisted drug delivery. Copyright © 2015 Elsevier B.V. All rights reserved.

Stabilized radio frequency quadrupole

DOEpatents

Lancaster, H.D.; Fugitt, J.A.; Howard, D.R.

1984-12-25

Disclosed is a long-vane stabilized radio frequency resonator for accelerating charged particles and including means defining a radio frequency resonator cavity, a plurality of long vanes mounted in the defining means for dividing the cavity into sections, and means interconnecting opposing ones of the plurality of vanes for stabilizing the resonator. 5 figs.

47 CFR 80.1019 - Antenna radio frequency indicator.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 5 2011-10-01 2011-10-01 false Antenna radio frequency indicator. 80.1019... Act § 80.1019 Antenna radio frequency indicator. Each nonportable bridge-to-bridge transmitter must be... indication when the transmitter is supplying power to the antenna transmission line or, in lieu thereof, a...

47 CFR 80.1019 - Antenna radio frequency indicator.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 5 2014-10-01 2014-10-01 false Antenna radio frequency indicator. 80.1019... Act § 80.1019 Antenna radio frequency indicator. Each nonportable bridge-to-bridge transmitter must be... indication when the transmitter is supplying power to the antenna transmission line or, in lieu thereof, a...

47 CFR 80.1019 - Antenna radio frequency indicator.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 47 Telecommunication 5 2012-10-01 2012-10-01 false Antenna radio frequency indicator. 80.1019... Act § 80.1019 Antenna radio frequency indicator. Each nonportable bridge-to-bridge transmitter must be... indication when the transmitter is supplying power to the antenna transmission line or, in lieu thereof, a...

47 CFR 80.1019 - Antenna radio frequency indicator.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 5 2013-10-01 2013-10-01 false Antenna radio frequency indicator. 80.1019... Act § 80.1019 Antenna radio frequency indicator. Each nonportable bridge-to-bridge transmitter must be... indication when the transmitter is supplying power to the antenna transmission line or, in lieu thereof, a...

47 CFR 80.1019 - Antenna radio frequency indicator.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 5 2010-10-01 2010-10-01 false Antenna radio frequency indicator. 80.1019... Act § 80.1019 Antenna radio frequency indicator. Each nonportable bridge-to-bridge transmitter must be... indication when the transmitter is supplying power to the antenna transmission line or, in lieu thereof, a...

48 CFR 552.211-92 - Radio Frequency Identification (RFID) using passive tags.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Identification (RFID) using passive tags. 552.211-92 Section 552.211-92 Federal Acquisition Regulations System... Provisions and Clauses 552.211-92 Radio Frequency Identification (RFID) using passive tags. As prescribed in 511.204(b)(11), insert the following clause: Radio Frequency Identification (RFID) Using Passive Tags...

48 CFR 552.211-92 - Radio Frequency Identification (RFID) using passive tags.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Identification (RFID) using passive tags. 552.211-92 Section 552.211-92 Federal Acquisition Regulations System... Provisions and Clauses 552.211-92 Radio Frequency Identification (RFID) using passive tags. As prescribed in 511.204(b)(11), insert the following clause: Radio Frequency Identification (RFID) Using Passive Tags...

Optical Tunable-Based Transmitter for Multiple Radio Frequency Bands

NASA Technical Reports Server (NTRS)

Nguyen, Hung (Inventor); Simons, Rainee N. (Inventor); Wintucky, Edwin G. (Inventor); Freeman, Jon C. (Inventor)

2016-01-01

An optical tunable transmitter is used to transmit multiple radio frequency bands on a single beam. More specifically, a tunable laser is configured to generate a plurality of optical wavelengths, and an optical tunable transmitter is configured to modulate each of the plurality of optical wavelengths with a corresponding radio frequency band. The optical tunable transmitter is also configured to encode each of the plurality of modulated optical wavelengths onto a single laser beam for transmission of a plurality of radio frequency bands using the single laser beam.

[Microstrip antenna design and system research of radio frequency identification temperature sensor].

PubMed

Yang, Hao; Yang, Xiaohe; Chen, Yuquan; Pan, Min

2008-12-01

Radio frequency identification sensor network, which is a product of integrating radio frequency identification (RFID) with wireless sensor network (WSN), is introduced in this paper. The principle of radio frequency identification sensor is analyzed, and the importance of the antenna is emphasized. Then three kinds of common antennae, namely coil antenna, dipole antenna and microstrip antenna, are discussed. Subsequently, according to requirement, we have designed a microstrip antenna in a wireless temperature-monitoring and controlling system. The measurement of factual effect showed the requirement was fulfilled.

The Speed of Sound and Attenuation of an IEC Agar-Based Tissue-Mimicking Material for High Frequency Ultrasound Applications

PubMed Central

Sun, Chao; Pye, Stephen D.; Browne, Jacinta E.; Janeczko, Anna; Ellis, Bill; Butler, Mairead B.; Sboros, Vassilis; Thomson, Adrian J.W.; Brewin, Mark P.; Earnshaw, Charles H.; Moran, Carmel M.

2012-01-01

This study characterized the acoustic properties of an International Electromechanical Commission (IEC) agar-based tissue mimicking material (TMM) at ultrasound frequencies in the range 10–47 MHz. A broadband reflection substitution technique was employed using two independent systems at 21°C ± 1°C. Using a commercially available preclinical ultrasound scanner and a scanning acoustic macroscope, the measured speeds of sound were 1547.4 ± 1.4 m∙s−1 and 1548.0 ± 6.1 m∙s−1, respectively, and were approximately constant over the frequency range. The measured attenuation (dB∙cm−1) was found to vary with frequency f (MHz) as 0.40f + 0.0076f2. Using this polynomial equation and extrapolating to lower frequencies give values comparable to those published at lower frequencies and can estimate the attenuation of this TMM in the frequency range up to 47 MHz. This characterisation enhances understanding in the use of this TMM as a tissue equivalent material for high frequency ultrasound applications. PMID:22502881

Inactivation of Enterobacter aerogenes in reconstituted skim milk by high- and low-frequency ultrasound.

PubMed

Gao, Shengpu; Hemar, Yacine; Lewis, Gillian D; Ashokkumar, Muthupandian

2014-11-01

The inactivation of Enterobacter aerogenes in skim milk using low-frequency (20kHz) and high-frequency (850kHz) ultrasonication was investigated. It was found that low-frequency acoustic cavitation resulted in lethal damage to E. aerogenes. The bacteria were more sensitive to ultrasound in water than in reconstituted skim milk having different protein concentrations. However, high-frequency ultrasound was not able to inactivate E. aerogenes in milk even when powers as high as 50W for 60min were used. This study also showed that high-frequency ultrasonication had no influence on the viscosity and particle size of skim milk, whereas low-frequency ultrasonication resulted in the decrease in viscosity and particle size of milk. The decrease in particle size is believed to be due to the breakup of the fat globules, and possibly to the cleavage of the κ-casein present at the surface of the casein micelles. Whey proteins were also found to be slightly affected by low-frequency ultrasound, with the amounts of α-lactalbumin and β-lactoglobulin slightly decreasing. Copyright © 2013. Published by Elsevier B.V.

How Are Uterine Fibroids Diagnosed?

MedlinePlus

... NICHD Research Information Find a Study More Information Pharmacology Condition Information NICHD Research Information Find a Study ... the uterus to help create the ultrasound image Magnetic resonance imaging (MRI), which uses magnets and radio waves to ...

Accurate step-FMCW ultrasound ranging and comparison with pulse-echo signaling methods

NASA Astrophysics Data System (ADS)

Natarajan, Shyam; Singh, Rahul S.; Lee, Michael; Cox, Brian P.; Culjat, Martin O.; Grundfest, Warren S.; Lee, Hua

2010-03-01

This paper presents a method setup for high-frequency ultrasound ranging based on stepped frequency-modulated continuous waves (FMCW), potentially capable of producing a higher signal-to-noise ratio (SNR) compared to traditional pulse-echo signaling. In current ultrasound systems, the use of higher frequencies (10-20 MHz) to enhance resolution lowers signal quality due to frequency-dependent attenuation. The proposed ultrasound signaling format, step-FMCW, is well-known in the radar community, and features lower peak power, wider dynamic range, lower noise figure and simpler electronics in comparison to pulse-echo systems. In pulse-echo ultrasound ranging, distances are calculated using the transmit times between a pulse and its subsequent echoes. In step-FMCW ultrasonic ranging, the phase and magnitude differences at stepped frequencies are used to sample the frequency domain. Thus, by taking the inverse Fourier transform, a comprehensive range profile is recovered that has increased immunity to noise over conventional ranging methods. Step-FMCW and pulse-echo waveforms were created using custom-built hardware consisting of an arbitrary waveform generator and dual-channel super heterodyne receiver, providing high SNR and in turn, accuracy in detection.

Real-time ultrasound-tagging to track the 2D motion of the common carotid artery wall in vivo

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zahnd, Guillaume, E-mail: g.zahnd@erasmusmc.nl; Salles, Sébastien; Liebgott, Hervé

2015-02-15

Purpose: Tracking the motion of biological tissues represents an important issue in the field of medical ultrasound imaging. However, the longitudinal component of the motion (i.e., perpendicular to the beam axis) remains more challenging to extract due to the rather coarse resolution cell of ultrasound scanners along this direction. The aim of this study is to introduce a real-time beamforming strategy dedicated to acquire tagged images featuring a distinct pattern in the objective to ease the tracking. Methods: Under the conditions of the Fraunhofer approximation, a specific apodization function was applied to the received raw channel data, in real-time duringmore » image acquisition, in order to introduce a periodic oscillations pattern along the longitudinal direction of the radio frequency signal. Analytic signals were then extracted from the tagged images, and subpixel motion tracking of the intima–media complex was subsequently performed offline, by means of a previously introduced bidimensional analytic phase-based estimator. Results: The authors’ framework was applied in vivo on the common carotid artery from 20 young healthy volunteers and 6 elderly patients with high atherosclerosis risk. Cine-loops of tagged images were acquired during three cardiac cycles. Evaluated against reference trajectories manually generated by three experienced analysts, the mean absolute tracking error was 98 ± 84 μm and 55 ± 44 μm in the longitudinal and axial directions, respectively. These errors corresponded to 28% ± 23% and 13% ± 9% of the longitudinal and axial amplitude of the assessed motion, respectively. Conclusions: The proposed framework enables tagged ultrasound images of in vivo tissues to be acquired in real-time. Such unconventional beamforming strategy contributes to improve tracking accuracy and could potentially benefit to the interpretation and diagnosis of biomedical images.« less

Ultrasonic tracking of shear waves using a particle filter

PubMed Central

Ingle, Atul N.; Ma, Chi; Varghese, Tomy

2015-01-01

Purpose: This paper discusses an application of particle filtering for estimating shear wave velocity in tissue using ultrasound elastography data. Shear wave velocity estimates are of significant clinical value as they help differentiate stiffer areas from softer areas which is an indicator of potential pathology. Methods: Radio-frequency ultrasound echo signals are used for tracking axial displacements and obtaining the time-to-peak displacement at different lateral locations. These time-to-peak data are usually very noisy and cannot be used directly for computing velocity. In this paper, the denoising problem is tackled using a hidden Markov model with the hidden states being the unknown (noiseless) time-to-peak values. A particle filter is then used for smoothing out the time-to-peak curve to obtain a fit that is optimal in a minimum mean squared error sense. Results: Simulation results from synthetic data and finite element modeling suggest that the particle filter provides lower mean squared reconstruction error with smaller variance as compared to standard filtering methods, while preserving sharp boundary detail. Results from phantom experiments show that the shear wave velocity estimates in the stiff regions of the phantoms were within 20% of those obtained from a commercial ultrasound scanner and agree with estimates obtained using a standard method using least-squares fit. Estimates of area obtained from the particle filtered shear wave velocity maps were within 10% of those obtained from B-mode ultrasound images. Conclusions: The particle filtering approach can be used for producing visually appealing SWV reconstructions by effectively delineating various areas of the phantom with good image quality properties comparable to existing techniques. PMID:26520761

Radio ultrasound observations of the fetotoxic effects in sheep from ingestion of Conium maculatum (poison-hemlock).

PubMed

Panter, K E; Bunch, T D; Keeler, R F; Sisson, D V

1988-01-01

Fetal movement in pregnant ewes gavaged with Conium maculatum (poison-hemlock) was reduced significantly, but temporarily. Fetal movement was observed by radio ultrasound at 45, 54 and 60 days of gestation in control ewes and on days 45, 54, and 60 of gestation immediately before and 1 hour following poison-hemlock feeding in treated ewes. Fetal movement was significantly reduced (P less than 0.01) 1 hour after poison-hemlock administration, but returned to normal within 18 hours post treatment. At parturition seven of eleven lambs born to seven treated ewes had varying degrees of front limb abnormalities. Modest to moderate flexure of the carpal joints, some lateral deviation in the front limbs at the pastern joint and kinked tails were observed. These malformations were transient and resolved spontaneously by 8 weeks after lambing.

Bypassing multidrug resistant ovarian cancer using ultrasound responsive doxorubicin/curcumin co-deliver alginate nanodroplets.

PubMed

Baghbani, Fatemeh; Moztarzadeh, Fathollah

2017-05-01

Ultrasound-responsive perfluorocarbon nanoemulsions are a class of new multifunctional smart nanocarriers which combine diagnostic properties with therapeutic properties and release their drug payload in a controlled manner in response to ultrasound. Therefore, combination therapy using chemotherapeutic and chemosensitizing agents co-entrapped in these nanocarriers seems beneficial for cancer treatment. In the present study, multifunctional smart alginate/perfluorohexane nanodroplets were developed for co-delivery of doxorubicin and curcumin (a strong chemosensitizer). The nanodroplets with the average particle size of 55.1nm were synthesized via nanoemulsion process. The entrapment efficiency of doxorubicin was 92.3%. To improve curcumin entrapment into the alginate shell, Span 60 was added to the formulation as a co-surfactant and finally curcumin entrapment of about 40% was achieved. Ultrasound-mediated drug release kinetic was evaluated at two different frequencies of 28kHz (low frequency) and 1MHz (high frequency). Low frequency ultrasound resulted in higher triggered drug release from nanodroplets. The nanodroplets showed strong ultrasound contrast via droplet to bubble transition as confirmed via B-mode ultrasound imaging. Enhanced cytotoxicity in adriamycin-resistant A2780 ovarian cancer cells was observed for Dox-Cur-NDs compared to Dox-NDs because of the synergistic effects of doxorubicin and curcumin. However, ultrasound irradiation significantly increased the cytotoxicity of Dox-Cur-NDs. Finally, in vivo ovarian cancer treatment using Dox/Cur-NDs combined with ultrasound irradiation resulted in efficient tumor regression. According to the present study, nanotherapy of multidrug resistant human ovarian cancer using ultrasound responsive doxorubicin/curcumin co-loaded alginate-shelled nanodroplets combined with ultrasound irradiation could be a promising modality for the future of cancer treatment. Copyright © 2017 Elsevier B.V. All rights reserved.

Backscattering analysis of high frequency ultrasonic imaging for ultrasound-guided breast biopsy

NASA Astrophysics Data System (ADS)

Cummins, Thomas; Akiyama, Takahiro; Lee, Changyang; Martin, Sue E.; Shung, K. Kirk

2017-03-01

A new ultrasound-guided breast biopsy technique is proposed. The technique utilizes conventional ultrasound guidance coupled with a high frequency embedded ultrasound array located within the biopsy needle to improve the accuracy in breast cancer diagnosis.1 The array within the needle is intended to be used to detect micro- calcifications indicative of early breast cancers such as ductal carcinoma in situ (DCIS). Backscattering analysis has the potential to characterize tissues to improve localization of lesions. This paper describes initial results of the application of backscattering analysis of breast biopsy tissue specimens and shows the usefulness of high frequency ultrasound for the new biopsy related technique. Ultrasound echoes of ex-vivo breast biopsy tissue specimens were acquired by using a single-element transducer with a bandwidth from 41 MHz to 88 MHz utilizing a UBM methodology, and the backscattering coefficients were calculated. These values as well as B-mode image data were mapped in 2D and matched with each pathology image for the identification of tissue type for the comparison to the pathology images corresponding to each plane. Microcalcifications were significantly distinguished from normal tissue. Adenocarcinoma was also successfully differentiated from adipose tissue. These results indicate that backscattering analysis is able to quantitatively distinguish tissues into normal and abnormal, which should help radiologists locate abnormal areas during the proposed ultrasound-guided breast biopsy with high frequency ultrasound.

Low-Frequency Beacon Signal Strength Determination.

DTIC Science & Technology

1980-01-01

Radio Frequency List , RIS AF-6050-12 [141. Using this value and assum- ing performance for these facilities as indicatcd in FAA Handbook 6050.10, ERP...FAA Handbook 6050. 10 for facilities of appropriate transmitter power, determined from FAA Master Radio Frequency List 6050-12, April 1979...these facilities has not been directly measured and, therefore, values corresponding to transmitter powers given in FAA Master Radio Frequency List , RIS

Dissimilar trend of nonlinearity in ultrasound transducers and systems at resonance and non-resonance frequencies.

PubMed

Ghasemi, Negareh; Zare, Firuz; Davari, Pooya; Vilathgamuwa, Mahinda; Ghosh, Arindam; Langton, Christian; Weber, Peter

2017-02-01

Several factors can affect performance of an ultrasound system such as quality of excitation signal and ultrasound transducer behaviour. Nonlinearity of piezoelectric ultrasound transducers is a key determinant in designing a proper driving power supply. Although, the nonlinearity of piezoelectric transducer impedance has been discussed in different literatures, the trend of the nonlinearity at different frequencies with respect to excitation voltage variations has not been clearly investigated in practice. In this paper, to demonstrate how the nonlinearity behaves, a sandwich piezoceramic transducer was excited at different frequencies. Different excitation signals were generated using a linear power amplifier and a multilevel converter within a range of 30-200V. Empirical relation was developed to express the resistance of the piezoelectric transducer as a nonlinear function of both excitation voltage and resonance frequency. The impedance measurements revealed that at higher voltage ranges, the piezoelectric transducer can be easily saturated. Also, it was shown that for the developed ultrasound system composed of two transducers (one transmitter and one receiver), the output voltage measured across receiver is a function of a voltage across the resistor in the RLC branches and is related to the resonance frequencies of the ultrasound transducer. Copyright © 2016 Elsevier B.V. All rights reserved.

Dual-Frequency Piezoelectric Transducers for Contrast Enhanced Ultrasound Imaging

PubMed Central

Martin, K. Heath; Lindsey, Brooks D.; Ma, Jianguo; Lee, Mike; Li, Sibo; Foster, F. Stuart; Jiang, Xiaoning; Dayton, Paul A.

2014-01-01

For many years, ultrasound has provided clinicians with an affordable and effective imaging tool for applications ranging from cardiology to obstetrics. Development of microbubble contrast agents over the past several decades has enabled ultrasound to distinguish between blood flow and surrounding tissue. Current clinical practices using microbubble contrast agents rely heavily on user training to evaluate degree of localized perfusion. Advances in separating the signals produced from contrast agents versus surrounding tissue backscatter provide unique opportunities for specialized sensors designed to image microbubbles with higher signal to noise and resolution than previously possible. In this review article, we describe the background principles and recent developments of ultrasound transducer technology for receiving signals produced by contrast agents while rejecting signals arising from soft tissue. This approach relies on transmitting at a low-frequency and receiving microbubble harmonic signals at frequencies many times higher than the transmitted frequency. Design and fabrication of dual-frequency transducers and the extension of recent developments in transducer technology for dual-frequency harmonic imaging are discussed. PMID:25375755

Dual-frequency piezoelectric transducers for contrast enhanced ultrasound imaging.

PubMed

Martin, K Heath; Lindsey, Brooks D; Ma, Jianguo; Lee, Mike; Li, Sibo; Foster, F Stuart; Jiang, Xiaoning; Dayton, Paul A

2014-11-04

For many years, ultrasound has provided clinicians with an affordable and effective imaging tool for applications ranging from cardiology to obstetrics. Development of microbubble contrast agents over the past several decades has enabled ultrasound to distinguish between blood flow and surrounding tissue. Current clinical practices using microbubble contrast agents rely heavily on user training to evaluate degree of localized perfusion. Advances in separating the signals produced from contrast agents versus surrounding tissue backscatter provide unique opportunities for specialized sensors designed to image microbubbles with higher signal to noise and resolution than previously possible. In this review article, we describe the background principles and recent developments of ultrasound transducer technology for receiving signals produced by contrast agents while rejecting signals arising from soft tissue. This approach relies on transmitting at a low-frequency and receiving microbubble harmonic signals at frequencies many times higher than the transmitted frequency. Design and fabrication of dual-frequency transducers and the extension of recent developments in transducer technology for dual-frequency harmonic imaging are discussed.

Ultrasound functional imaging in an ex vivo beating porcine heart platform

NASA Astrophysics Data System (ADS)

Petterson, Niels J.; Fixsen, Louis S.; Rutten, Marcel C. M.; Pijls, Nico H. J.; van de Vosse, Frans N.; Lopata, Richard G. P.

2017-12-01

In recent years, novel ultrasound functional imaging (UFI) techniques have been introduced to assess cardiac function by measuring, e.g. cardiac output (CO) and/or myocardial strain. Verification and reproducibility assessment in a realistic setting remain major issues. Simulations and phantoms are often unrealistic, whereas in vivo measurements often lack crucial hemodynamic parameters or ground truth data, or suffer from the large physiological and clinical variation between patients when attempting clinical validation. Controlled validation in certain pathologies is cumbersome and often requires the use of lab animals. In this study, an isolated beating pig heart setup was adapted and used for performance assessment of UFI techniques such as volume assessment and ultrasound strain imaging. The potential of performing verification and reproducibility studies was demonstrated. For proof-of-principle, validation of UFI in pathological hearts was examined. Ex vivo porcine hearts (n  =  6, slaughterhouse waste) were resuscitated and attached to a mock circulatory system. Radio frequency ultrasound data of the left ventricle were acquired in five short axis views and one long axis view. Based on these slices, the CO was measured, where verification was performed using flow sensor measurements in the aorta. Strain imaging was performed providing radial, circumferential and longitudinal strain to assess reproducibility and inter-subject variability under steady conditions. Finally, strains in healthy hearts were compared to a heart with an implanted left ventricular assist device, simulating a failing, supported heart. Good agreement between ultrasound and flow sensor based CO measurements was found. Strains were highly reproducible (intraclass correlation coefficients  >0.8). Differences were found due to biological variation and condition of the hearts. Strain magnitude and patterns in the assisted heart were available for different pump action, revealing large changes compared to the normal condition. The setup provides a valuable benchmarking platform for UFI techniques. Future studies will include work on different pathologies and other means of measurement verification.

Enhanced therapeutic anti-inflammatory effect of betamethasone on topical administration with low-frequency, low-intensity (20 kHz, 100 mW/cm(2)) ultrasound exposure on carrageenan-induced arthritis in a mouse model.

PubMed

Cohen, Gadi; Natsheh, Hiba; Sunny, Youhan; Bawiec, Christopher R; Touitou, Elka; Lerman, Melissa A; Lazarovici, Philip; Lewin, Peter A

2015-09-01

The purpose of this work was to investigate whether low-frequency, low-intensity (20 kHz, <100 mW/cm(2), spatial-peak, temporal-peak intensity) ultrasound, delivered with a lightweight (<100 g), tether-free, fully wearable, battery-powered applicator, is capable of reducing inflammation in a mouse model of rheumatoid arthritis. The therapeutic, acute, anti-inflammatory effect was estimated from the relative swelling induced in mice hindlimb paws. In an independent, indirect approach, the inflammation was bio-imaged by measuring glycolytic activity with near-infrared labeled 2-deoxyglucose. The outcome of the experiments indicated that the combination of ultrasound exposure and topical application of 0.1% (w/w) betamethasone gel resulted in statistically significantly (p < 0.05) enhanced anti-inflammatory activity in comparison with drug or ultrasound treatment alone. The present study underscores the potential benefits of low-frequency, low-intensity ultrasound-assisted drug delivery. However, the proof of concept presented indicates the need for additional experiments to systematically evaluate and optimize the potential of, and the conditions for, tolerable low-frequency, low-intensity ultrasound-promoted non-invasive drug delivery. Copyright © 2015 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

Synergism of aspirin and heparin with a low-frequency non-invasive ultrasound system for augmentation of in-vitro clot lysis.

PubMed

Atar, Shaul; Neuman, Yoram; Miyamoto, Takashi; Chen, Ming; Birnbaum, Yochai; Luo, Huai; Kobal, Sergio; Siegel, Robert J

2003-06-01

Aspirin, glycoprotein IIb/IIIa inhibitors and heparin are routinely used in acute coronary syndromes. Previously we showed that there is synergism between ultrasound and heparin and tirofiban in augmenting blood clot disruption. However, there is a little data on a possible synergism of low-frequency ultrasound with aspirin for in-vitro clot dissolution, and especially on the combination of aspirin with heparin and/or glycoprotein IIb/IIIa inhibitors. Human blood clots (n = 320) were incubated for 10 or 20 minutes in saline containing aspirin alone or combined with heparin and/or tirofiban and/or eptifibatide. Clots were randomly treated with low-frequency ultrasound (27.3 kHz) or incubation only. The percent clot weight loss and the incremental effect of ultrasound were calculated. The most significant incremental effect of ultrasound on clot weight reduction was detected with aspirin alone (5.2 +/- 2.3% and 5.2 +/- 2.6% after 10' and 20', p = 0.04 and p = 0.06, respectively) and in combination with heparin (8.8 +/- 2.5% and 11.5 +/- 2.7% after 10' and 20', p = 0.01 and p = 0.0001, respectively). The greatest absolute magnitude of clot weight reduction was observed with ultrasound combined with aspirin and heparin (48.5 +/- 9.5% after 20'). The addition of tirofiban or eptifibatide to aspirin, heparin and ultrasound did not increase clot lysis. However, eptifibatide had significantly better synergism than tirofiban (p = 0.025 and p = 0.015, after 10 and 20 minutes, respectively). Aspirin alone or in combination with heparin results in significant augmentation of clot lysis and is synergistic with application of low-frequency ultrasound for 10 and 20 minutes only. These results may have important implications for a possible use of low-frequency ultrasound in treatment algorithms of acute coronary syndromes.

Noncontact, Low Frequency Ultrasound as an Effective Therapy against Pseudomonas aeruginosa-infected Biofilm Wounds

DTIC Science & Technology

2013-03-01

venous ulcers: themes and stories about their impact on quality of life. Ostomy Wound Manage 1998; 44: 38–49. 4. Mustoe TA, O’Shaughnessy K, Kloeters...double-blind, controlled, multi- center study. Ostomy Wound Manage 2005; 51: 24–39. 29. Ennis WJ, Valdes W, Gainer M, Meneses P. Evaluation of clini...frequency, nonthermal ultrasound in burn care. Ostomy Wound Manage 2008; 54: 66–9. 33. Kavros SJ, Schenck EC. Use of noncontact low-frequency ultrasound in

Ultrasound Imaging of DNA-Damage Effects in Live Cultured Cells and in Brain Tissue.

PubMed

Tadayyon, Hadi; Gangeh, Mehrdad J; Vlad, Roxana; Kolios, Michael C; Czarnota, Gregory J

2017-01-01

High-frequency ultrasound (>20 MHz) spectroscopy can be used to detect noninvasively DNA damage in cell samples in vitro, and in live tissue both ex vivo and in vivo. This chapter focuses on the former two aspects. Experimental evidence suggests that morphological changes that occur in cells undergoing apoptosis result in changes in frequency-dependent ultrasound backscatter. With advances in research, ultrasound spectroscopy is advancing the boundaries of fast, label-free, noninvasive DNA damage detection technology with potential use in personalized medicine and early therapy response monitoring. Depending on the desired resolution, parametric ultrasound images can be computed and displayed within minutes to hours after ultrasound examination for cell death.

A high pulse repetition frequency ultrasound system for the ex vivo measurement of mechanical properties of crystalline lenses with laser-induced microbubbles interrogated by acoustic radiation force.

PubMed

Yoon, Sangpil; Aglyamov, Salavat; Karpiouk, Andrei; Emelianov, Stanislav

2012-08-07

A high pulse repetition frequency ultrasound system for an ex vivo measurement of mechanical properties of an animal crystalline lens was developed and validated. We measured the bulk displacement of laser-induced microbubbles created at different positions within the lens using nanosecond laser pulses. An impulsive acoustic radiation force was applied to the microbubble, and spatio-temporal measurements of the microbubble displacement were assessed using a custom-made high pulse repetition frequency ultrasound system consisting of two 25 MHz focused ultrasound transducers. One of these transducers was used to emit a train of ultrasound pulses and another transducer was used to receive the ultrasound echoes reflected from the microbubble. The developed system was operating at 1 MHz pulse repetition frequency. Based on the measured motion of the microbubble, Young's moduli of surrounding tissue were reconstructed and the values were compared with those measured using the indentation test. Measured values of Young's moduli of four bovine lenses ranged from 2.6 ± 0.1 to 26 ± 1.4 kPa, and there was good agreement between the two methods. Therefore, our studies, utilizing the high pulse repetition frequency ultrasound system, suggest that the developed approach can be used to assess the mechanical properties of ex vivo crystalline lenses. Furthermore, the potential of the presented approach for in vivo measurements is discussed.

Characterization of enzymatically induced degradation of articular cartilage using high frequency ultrasound

NASA Astrophysics Data System (ADS)

Töyräs, J.; Rieppo, J.; Nieminen, M. T.; Helminen, H. J.; Jurvelin, J. S.

1999-11-01

Ultrasound may provide a quantitative technique for the characterization of cartilage changes typical of early osteoarthrosis. In this study, specific changes in bovine articular cartilage were induced using collagenase and chondroitinase ABC, enzymes that selectively degrade collagen fibril network and digest proteoglycans, respectively. Changes in cartilage structure and properties were quantified using high frequency ultrasound, microscopic analyses and mechanical indentation tests. The ultrasound reflection coefficient of the physiological saline-cartilage interface (R1) decreased significantly (-96.4%, p<0.01) in the collagenase digested cartilage compared to controls. Also a significantly lower ultrasound velocity (-6.2%, p<0.01) was revealed after collagenase digestion. After chondroitinase ABC digestion, a new acoustic interface at the depth of the enzyme penetration front was detected. Cartilage thickness, as determined with ultrasound, showed a high, linear correlation (R = 0.943, n = 60, average difference 0.073 mm (4.0%)) with the thickness measured by the needle-probe method. Both enzymes induced a significant decrease in the Young's modulus of cartilage (p<0.01). Our results indicate that high frequency ultrasound provides a sensitive technique for the analysis of cartilage structure and properties. Possibly ultrasound may be utilized in vivo as a quantitative probe during arthroscopy.

Rectenna for high-voltage applications

NASA Technical Reports Server (NTRS)

Epp, Larry W. (Inventor); Khan, Abdur R. (Inventor)

2002-01-01

An energy transfer system is disclosed. The system includes patch elements, shielding layers, and energy rectifying circuits. The patch elements receive and couple radio frequency energy. The shielding layer includes at least one opening that allows radio frequency energy to pass through. The openings are formed and positioned to receive the radio frequency energy and to minimize any re-radiating back toward the source of energy. The energy rectifying circuit includes a circuit for rectifying the radio frequency energy into dc energy. A plurality of energy rectifying circuits is arranged in an array to provide a sum of dc energy generated by the energy rectifying circuit.

Multi-mode radio frequency device

DOEpatents

Gilbert, Ronald W [Morgan Hill, CA; Carrender, Curtis Lee [Morgan Hill, CA; Anderson, Gordon A [Benton City, WA; Steele, Kerry D [Kennewick, WA

2007-02-13

A transponder device having multiple modes of operation, such as an active mode and a passive mode, wherein the modes of operation are selected in response to the strength of a received radio frequency signal. A communication system is also provided having a transceiver configured to transmit a radio frequency signal and to receive a responsive signal, and a transponder configured to operate in a plurality of modes and to activate modes of operation in response to the radio frequency signal. Ideally, each mode of operation is activated and deactivated independent of the other modes, although two or more modes may be concurrently operational.

Cavitation thresholds of contrast agents in an in vitro human clot model exposed to 120-kHz ultrasound.

PubMed

Gruber, Matthew J; Bader, Kenneth B; Holland, Christy K

2014-02-01

Ultrasound contrast agents (UCAs) can be employed to nucleate cavitation to achieve desired bioeffects, such as thrombolysis, in therapeutic ultrasound applications. Effective methods of enhancing thrombolysis with ultrasound have been examined at low frequencies (<1 MHz) and low amplitudes (<0.5 MPa). The objective of this study was to determine cavitation thresholds for two UCAs exposed to 120-kHz ultrasound. A commercial ultrasound contrast agent (Definity(®)) and echogenic liposomes were investigated to determine the acoustic pressure threshold for ultraharmonic (UH) and broadband (BB) generation using an in vitro flow model perfused with human plasma. Cavitation emissions were detected using two passive receivers over a narrow frequency bandwidth (540-900 kHz) and a broad frequency bandwidth (0.54-1.74 MHz). UH and BB cavitation thresholds occurred at the same acoustic pressure (0.3 ± 0.1 MPa, peak to peak) and were found to depend on the sensitivity of the cavitation detector but not on the nucleating contrast agent or ultrasound duty cycle.

Time-Frequency and Non-Laplacian Phenomena at Radio Frequencies

DTIC Science & Technology

2017-01-22

Unlimited UU UU UU UU 22-01-2017 30-Sep-2012 30-Sep-2016 Final Report: Time -Frequency and Non-Laplacian Phenomena at Radio Frequencies The views...average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data... Time ‐Frequency and Non‐Laplacian Phenomena at Radio Frequencies  U.S. Army Research Office grant W911NF‐12‐1‐0526  Michael B. Steer  Department of

Graphene electrostatic microphone and ultrasonic radio

PubMed Central

Zhou, Qin; Zheng, Jinglin; Onishi, Seita; Crommie, M. F.; Zettl, Alex K.

2015-01-01

We present a graphene-based wideband microphone and a related ultrasonic radio that can be used for wireless communication. It is shown that graphene-based acoustic transmitters and receivers have a wide bandwidth, from the audible region (20∼20 kHz) to the ultrasonic region (20 kHz to at least 0.5 MHz). Using the graphene-based components, we demonstrate efficient high-fidelity information transmission using an ultrasonic band centered at 0.3 MHz. The graphene-based microphone is also shown to be capable of directly receiving ultrasound signals generated by bats in the field, and the ultrasonic radio, coupled to electromagnetic (EM) radio, is shown to function as a high-accuracy rangefinder. The ultrasonic radio could serve as a useful addition to wireless communication technology where the propagation of EM waves is difficult. PMID:26150483

47 CFR 2.815 - External radio frequency power amplifiers.

Code of Federal Regulations, 2014 CFR

2014-10-01

... amplifier is any device which, (1) when used in conjunction with a radio transmitter as a signal source is capable of amplification of that signal, and (2) is not an integral part of a radio transmitter as... following: (1) The external radio frequency power amplifier shall not be capable of amplification in the...

47 CFR 2.815 - External radio frequency power amplifiers.

Code of Federal Regulations, 2013 CFR

2013-10-01

... amplifier is any device which, (1) when used in conjunction with a radio transmitter as a signal source is capable of amplification of that signal, and (2) is not an integral part of a radio transmitter as... following: (1) The external radio frequency power amplifier shall not be capable of amplification in the...

47 CFR 2.815 - External radio frequency power amplifiers.

Code of Federal Regulations, 2012 CFR

2012-10-01

... amplifier is any device which, (1) when used in conjunction with a radio transmitter as a signal source is capable of amplification of that signal, and (2) is not an integral part of a radio transmitter as... following: (1) The external radio frequency power amplifier shall not be capable of amplification in the...

A low frequency RFI monitoring system

NASA Astrophysics Data System (ADS)

Amiri, Shahram; Shankar, N. Udaya; Girish, B. S.; Somashekar, R.

Radio frequency interference (RFI) is a growing problem for research in radio astronomy particularly at wavelengths longer than 2m. For satisfactory operation of a radio telescope, several bands have been protected for radio astronomy observations by the International Telecommunication Union. Since the radiation from cosmic sources are typically 40 to 100 dB below the emission from services operating in unprotected bands, often the out-of-band emission limits the sensitivity of astronomical observations. Moreover, several radio spectral emissions from cosmic sources are present in the frequency range outside the allocated band for radio astronomy. Thus monitoring of RFI is essential before building a receiver system for low frequency radio astronomy. We describe the design and development of an RFI monitoring system operating in the frequency band 30 to 100 MHz. This was designed keeping in view our proposal to extend the frequency of operation of GMRT down to 40 MHz. The monitor is a PC based spectrometer recording the voltage output of a receiver connected to an antenna, capable of digitizing the low frequency RF directly with an 8 bit ADC and sampling bandwidths up to 16 MHz. The system can operate continuously in almost real-time with a loss of only 2% of data. Here we will present the systems design aspects and the results of RFI monitoring carried out at the Raman Research Institute, Bangalore and at the GMRT site in Khodad.

Fox-7 for Insensitive Boosters

DTIC Science & Technology

2010-08-01

cavitation , and therefore nucleation, to occur at each frequency. As well as producing ultrasound at different frequencies, the method of delivery of...processing techniques using ultrasound , designed to optimise FOX-7 crystal size and morphology to improve booster formulations, and results from these...7 booster formulations. Also included are particle processing techniques using ultrasound , designed to optimise FOX-7 crystal size and morphology

Ultrasound Enhanced Matrix Metalloproteinase-9 Triggered Release of Contents from Echogenic Liposomes

PubMed Central

Nahire, Rahul; Paul, Shirshendu; Scott, Michael D.; Singh, Raushan K.; Muhonen, Wallace W.; Shabb, John; Gange, Kara N.; Srivastava, D. K.; Sarkar, Kausik; Mallik, Sanku

2012-01-01

The extracellular enzyme matrix metalloproteinase-9 (MMP-9) is overexpressed in atherosclerotic plaques and in metastatic cancers. The enzyme is responsible for rupture of the plaques and for the invasion and metastasis of a large number of cancers. The ability of ultrasonic excitation to induce thermal and mechanical effects has been used to release drugs from different carriers. However, majority of these studies were performed with low frequency ultrasound (LFUS) at kHz frequencies. Clinical usage of LFUS excitations will be limited due to harmful biological effects. Herein, we report our results on the release of encapsulated contents from substrate lipopeptide incorporated echogenic liposomes triggered by recombinant human MMP-9. The contents release was further enhanced by the application of diagnostic frequency (3 MHz) ultrasound. The echogenic liposomes were successfully imaged employing a medical ultrasound transducer (4 – 15 MHz). The conditioned cell culture media from cancer cells (secreting MMP-9) released the encapsulated dye from the liposomes (30 – 50%) and this release is also increased (50 – 80%) by applying diagnostic frequency ultrasound (3 MHz) for 3 minutes. With further developments, these liposomes have the potential to serve as multimodal carriers for triggered release and simultaneous ultrasound imaging. PMID:22849291

Planck Early Results. XV. Spectral Energy Distributions and Radio Continuum Spectra of Northern Extragalactic Radio Sources

NASA Technical Reports Server (NTRS)

Aatrokoski, J.; Ade, P. A. R.; Aghanim, N.; Aller, H. D.; Aller, M. F.; Angelakis, E.; Amaud, M.; Ashdown, M.; Aumont, J.; Baccigalupi, C.;

Multi-messenger astronomy of gravitational-wave sources with flexible wide-area radio transient surveys

NASA Astrophysics Data System (ADS)

Kavic, Michael; Cregg C. Yancey, Brandon E. Bear, Bernadine Akukwe, Kevin Chen, Jayce Dowell, Jonathan D. Gough, Jonah Kanner, Kenneth Obenberger, Peter Shawhan, John H. Simonetti , Gregory B. Taylor , Jr-Wei Tsai

2016-01-01

We explore opportunities for multi-messenger astronomy using gravitational waves (GWs) and prompt, transient low-frequency radio emission to study highly energetic astrophysical events. We review the literature on possible sources of correlated emission of GWs and radio transients, highlighting proposed mechanisms that lead to a short-duration, high-flux radio pulse originating from the merger of two neutron stars or from a superconducting cosmic string cusp. We discuss the detection prospects for each of these mechanisms by low-frequency dipole array instruments such as LWA1, the Low Frequency Array and the Murchison Widefield Array. We find that a broad range of models may be tested by searching for radio pulses that, when de-dispersed, are temporally and spatially coincident with a LIGO/Virgo GW trigger within a ˜30 s time window and ˜200-500 deg(2) sky region. We consider various possible observing strategies and discuss their advantages and disadvantages. Uniquely, for low-frequency radio arrays, dispersion can delay the radio pulse until after low-latency GW data analysis has identified and reported an event candidate, enabling a prompt radio signal to be captured by a deliberately targeted beam. If neutron star mergers do have detectable prompt radio emissions, a coincident search with the GW detector network and low-frequency radio arrays could increase the LIGO/Virgo effective search volume by up to a factor of ˜2. For some models, we also map the parameter space that may be constrained by non-detections.

Multi-messenger Astronomy of Gravitational-wave Sources with Flexible Wide-area Radio Transient Surveys

NASA Astrophysics Data System (ADS)

Yancey, Cregg C.; Bear, Brandon E.; Akukwe, Bernadine; Chen, Kevin; Dowell, Jayce; Gough, Jonathan D.; Kanner, Jonah; Kavic, Michael; Obenberger, Kenneth; Shawhan, Peter; Simonetti, John H.; -Wei Tsai, Gregory B. Taylor, Jr.

2015-10-01

We explore opportunities for multi-messenger astronomy using gravitational waves (GWs) and prompt, transient low-frequency radio emission to study highly energetic astrophysical events. We review the literature on possible sources of correlated emission of GWs and radio transients, highlighting proposed mechanisms that lead to a short-duration, high-flux radio pulse originating from the merger of two neutron stars or from a superconducting cosmic string cusp. We discuss the detection prospects for each of these mechanisms by low-frequency dipole array instruments such as LWA1, the Low Frequency Array and the Murchison Widefield Array. We find that a broad range of models may be tested by searching for radio pulses that, when de-dispersed, are temporally and spatially coincident with a LIGO/Virgo GW trigger within a ˜30 s time window and ˜200-500 deg2 sky region. We consider various possible observing strategies and discuss their advantages and disadvantages. Uniquely, for low-frequency radio arrays, dispersion can delay the radio pulse until after low-latency GW data analysis has identified and reported an event candidate, enabling a prompt radio signal to be captured by a deliberately targeted beam. If neutron star mergers do have detectable prompt radio emissions, a coincident search with the GW detector network and low-frequency radio arrays could increase the LIGO/Virgo effective search volume by up to a factor of ˜2. For some models, we also map the parameter space that may be constrained by non-detections.

A high-frequency transimpedance amplifier for CMOS integrated 2D CMUT array towards 3D ultrasound imaging.

PubMed

Huang, Xiwei; Cheong, Jia Hao; Cha, Hyouk-Kyu; Yu, Hongbin; Je, Minkyu; Yu, Hao

2013-01-01

One transimpedance amplifier based CMOS analog front-end (AFE) receiver is integrated with capacitive micromachined ultrasound transducers (CMUTs) towards high frequency 3D ultrasound imaging. Considering device specifications from CMUTs, the TIA is designed to amplify received signals from 17.5MHz to 52.5MHz with center frequency at 35MHz; and is fabricated in Global Foundry 0.18-µm 30-V high-voltage (HV) Bipolar/CMOS/DMOS (BCD) process. The measurement results show that the TIA with power-supply 6V can reach transimpedance gain of 61dBΩ and operating frequency from 17.5MHz to 100MHz. The measured input referred noise is 27.5pA/√Hz. Acoustic pulse-echo testing is conducted to demonstrate the receiving functionality of the designed 3D ultrasound imaging system.

47 CFR 90.357 - Frequencies for LMS systems in the 902-928 MHz band.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 5 2010-10-01 2010-10-01 false Frequencies for LMS systems in the 902-928 MHz band. 90.357 Section 90.357 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Intelligent Transportation Systems Radio Service § 90.357 Frequencies for LMS systems in...

Validation of musculoskeletal ultrasound to assess and quantify muscle glycogen content. A novel approach.

PubMed

Hill, John C; Millán, Iñigo San

2014-09-01

Glycogen storage is essential for exercise performance. The ability to assess muscle glycogen levels should be an important advantage for performance. However, skeletal muscle glycogen assessment has only been available and validated through muscle biopsy. We have developed a new methodology using high-frequency ultrasound to assess skeletal muscle glycogen content in a rapid, portable, and noninvasive way using MuscleSound (MuscleSound, LCC, Denver, CO) technology. To validate the utilization of high-frequency musculoskeletal ultrasound for muscle glycogen assessment and correlate it with histochemical glycogen quantification through muscle biopsy. Twenty-two male competitive cyclists (categories: Pro, 1-4; average height, 183.7 ± 4.9 cm; average weight, 76.8 ± 7.8 kg) performed a steady-state test on a cyclergometer for 90 minutes at a moderate to high exercise intensity, eliciting a carbohydrate oxidation of 2-3 g·min⁻¹ and a blood lactate concentration of 2 to 3 mM. Pre- and post-exercise glycogen content from rectus femoris muscle was measured using histochemical analysis through muscle biopsy and through high-frequency ultrasound scans using MuscleSound technology. Correlations between muscle biopsy glycogen histochemical quantification (mmol·kg⁻¹) and high-frequency ultrasound methodology through MuscleSound technology were r = 0.93 (P < 0.0001) pre-exercise and r = 0.94 (P < 0.0001) post-exercise. The correlation between muscle biopsy glycogen quantification and high-frequency ultrasound methodology for the change in glycogen from pre- and post-exercise was r = 0.81 (P < 0.0001). These results demonstrate that skeletal muscle glycogen can be measured quickly and noninvasively through high-frequency ultrasound using MuscleSound technology.

A Comparison of 1- and 3.2-MHz Low-Intensity Pulsed Ultrasound on Osteogenesis on Porous Titanium Alloy Scaffolds: An In Vitro and In Vivo Study.

PubMed

Feng, Lifang; Liu, Xiaohan; Cao, Hongjuan; Qin, Limei; Hou, Wentao; Wu, Lin

2018-05-21

Low-intensity pulsed ultrasound (LIPUS) combined with porous scaffolds can be used as a new therapy to treat bone defect repair. The aim of this study was to evaluate the effects of 1 and 3.2 MHz LIPUS on osteogenesis on porous Ti64 alloy scaffolds for both in vitro and in vivo studies. Scaffolds were randomly divided into the high-frequency ultrasound group, low-frequency ultrasound group, and control group. Mouse pre-osteoblast cells were cultured with porous Ti-6Al-4V scaffolds in vitro to evaluate cell proliferation and differentiation. In addition, scaffolds were implanted into rabbit mandibular defects in vivo. The effects of LIPUS on bone regeneration were evaluated by observing the micro-computed tomography (micro-CT), toluidine blue staining, and von Kossa staining. The results revealed no significant difference in the cell counting kit-8 values between the ultrasound groups and control groups (P > .05). Compared with the control group, ultrasound promoted alkaline phosphatase activity and osteocalcin levels of the cells on the scaffolds (P < .05), but there was no significant difference between the two frequencies. In addition, histomorphologic analyses revealed that the volume and amount of new bone formation increased and that bone maturity improved in the ultrasound groups compared with the control group, but no significant difference was noted between the two frequencies. Under the present experimental conditions, LIPUS promoted osteoblast differentiation and promoted bone maturity on porous Ti64 scaffolds. No significant differences were noted between the two frequencies. © 2018 by the American Institute of Ultrasound in Medicine.

Wide band stepped frequency ground penetrating radar

DOEpatents

Bashforth, M.B.; Gardner, D.; Patrick, D.; Lewallen, T.A.; Nammath, S.R.; Painter, K.D.; Vadnais, K.G.

1996-03-12

A wide band ground penetrating radar system is described embodying a method wherein a series of radio frequency signals is produced by a single radio frequency source and provided to a transmit antenna for transmission to a target and reflection therefrom to a receive antenna. A phase modulator modulates those portions of the radio frequency signals to be transmitted and the reflected modulated signal is combined in a mixer with the original radio frequency signal to produce a resultant signal which is demodulated to produce a series of direct current voltage signals, the envelope of which forms a cosine wave shaped plot which is processed by a Fast Fourier Transform Unit 44 into frequency domain data wherein the position of a preponderant frequency is indicative of distance to the target and magnitude is indicative of the signature of the target. 6 figs.

Single-transducer dual-frequency ultrasound generation to enhance acoustic cavitation.

PubMed

Liu, Hao-Li; Hsieh, Chao-Ming

2009-03-01

Dual- or multiple-frequency ultrasound stimulation is capable of effectively enhancing the acoustic cavitation effect over single-frequency ultrasound. Potential application of this sonoreactor design has been widely proposed such as on sonoluminescence, sonochemistry enhancement, and transdermal drug release enhancement. All currently available sonoreactor designs employed multiple piezoelectric transducers for generating single-frequency ultrasonic waves separately and then these waves were mixed and interfered in solutions. The purpose of this research is to propose a novel design of generating dual-frequency ultrasonic waves with single piezoelectric elements, thereby enhancing acoustic cavitation. Macroscopic bubbles were detected optically, and they were quantified at either a single-frequency or for different frequency combinations for determining their efficiency for enhancing acoustic cavitation. Visible bubbles were optically detected and hydrogen peroxide was measured to quantify acoustic cavitation. Test water samples with different gas concentrations and different power levels were used to determine the efficacy of enhancing acoustic cavitation of this design. The spectrum obtained from the backscattered signals was also recorded and examined to confirm the occurrence of stable cavitation. The results confirmed that single-element dual-frequency ultrasound stimulation can enhance acoustic cavitation. Under certain testing conditions, the generation of bubbles can be enhanced up to a level of five times higher than the generation of bubbles in single-frequency stimulation, and can increase the hydrogen peroxide production up to an increase of one fold. This design may serve as a useful alternative for future sonoreactor design owing to its simplicity to produce dual- or multiple-frequency ultrasound.

The development and evaluation of ultrasound for the treatment of bacterial suspensions. A study of frequency, power and sonication time on cultured Bacillus species.

PubMed

Joyce, E; Phull, S S; Lorimer, J P; Mason, T J

2003-10-01

Some species of bacteria produce colonies and spores which agglomerate in spherical clusters (Bacillus subtilis) and this serves as a protection for the organisms inside against biocidal attack. Flocs of fine particles e.g. clay can entrap bacteria which can also protect them against the biocides. It is because of problems such as these that alternative methods of disinfecting water are under active investigation. One such method is the use of power ultrasound, either alone or in combination with other methods. Ultrasound is able to inactivate bacteria and deagglomerate bacterial clusters or flocs through a number of physical, mechanical and chemical effects arising from acoustic cavitation. The aim of this study was to investigate the effect of power ultrasound at different powers and frequencies on Bacillus subtilis. Viable plate count techniques were used as a measure of microbial activity. Results showed a significant increase in percent kill for Bacillus species with increasing duration of exposure and intensity of ultrasound in the low-kilohertz range (20 and 38 kHz). Results obtained at two higher frequencies (512 and 850 kHz) indicated a significant increase in bacteria count suggesting declumping. In assessing the bacterial kill with time under different sonication regimes three types of behaviour were characterized: High power ultrasound (lower frequencies) in low volumes of bacterial suspension results in a continuous reduction in bacterial cell numbers i.e. the kill rate predominates. High power ultrasound (lower frequencies) in larger volumes results in an initial rise in cell numbers suggesting declumping of the bacteria but this initial rise then falls as the declumping finishes and the kill rate becomes more important. Low intensity ultrasound (higher frequencies) gives an initial rise in cell numbers as a result of declumping. The kill rate is low and so there is no significant subsequent decrease in bacterial cell numbers.

Challenges and regulatory considerations in the acoustic measurement of high-frequency (>20 MHz) ultrasound.

PubMed

Nagle, Samuel M; Sundar, Guru; Schafer, Mark E; Harris, Gerald R; Vaezy, Shahram; Gessert, James M; Howard, Samuel M; Moore, Mary K; Eaton, Richard M

2013-11-01

This article examines the challenges associated with making acoustic output measurements at high ultrasound frequencies (>20 MHz) in the context of regulatory considerations contained in the US Food and Drug Administration industry guidance document for diagnostic ultrasound devices. Error sources in the acoustic measurement, including hydrophone calibration and spatial averaging, nonlinear distortion, and mechanical alignment, are evaluated, and the limitations of currently available acoustic measurement instruments are discussed. An uncertainty analysis of acoustic intensity and power measurements is presented, and an example uncertainty calculation is done on a hypothetical 30-MHz high-frequency ultrasound system. This analysis concludes that the estimated measurement uncertainty of the acoustic intensity is +73%/-86%, and the uncertainty in the mechanical index is +37%/-43%. These values exceed the respective levels in the Food and Drug Administration guidance document of 30% and 15%, respectively, which are more representative of the measurement uncertainty associated with characterizing lower-frequency ultrasound systems. Recommendations made for minimizing the measurement uncertainty include implementing a mechanical positioning system that has sufficient repeatability and precision, reconstructing the time-pressure waveform via deconvolution using the hydrophone frequency response, and correcting for hydrophone spatial averaging.

Ultrasound Assessment of Human Meniscus.

PubMed

Viren, Tuomas; Honkanen, Juuso T; Danso, Elvis K; Rieppo, Lassi; Korhonen, Rami K; Töyräs, Juha

2017-09-01

The aim of the present study was to evaluate the applicability of ultrasound imaging to quantitative assessment of human meniscus in vitro. Meniscus samples (n = 26) were harvested from 13 knee joints of non-arthritic human cadavers. Subsequently, three locations (anterior, center and posterior) from each meniscus were imaged with two ultrasound transducers (frequencies 9 and 40 MHz), and quantitative ultrasound parameters were determined. Furthermore, partial-least-squares regression analysis was applied for ultrasound signal to determine the relations between ultrasound scattering and meniscus integrity. Significant correlations between measured and predicted meniscus compositions and mechanical properties were obtained (R 2  = 0.38-0.69, p < 0.05). The relationship between conventional ultrasound parameters and integrity of the meniscus was weaker. To conclude, ultrasound imaging exhibited a potential for evaluation of meniscus integrity. Higher ultrasound frequency combined with multivariate analysis of ultrasound backscattering was found to be the most sensitive for evaluation of meniscus integrity. Copyright © 2017 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

[Study on assistant cleaning of ultrasound for the ultrafiltration membrane].

PubMed

Zhang, Guojun; Liu, Zhongzhou

2003-11-01

The effects of ultrasounds with different frequency on membrane performance were investigated in this paper. The experimental results show that there were nearly no effects of 20 W ultrasound on membrane retention coefficient, but it decreased seriously when the ultrasound power was above 30 W. On the basis of these results, low frequency ultrasound (20 W) was introduced to assist the chemical cleaning in the ultrafiltration process of wastewater from bank note printing works. The cleaning time could be shortened from 20-30 min to 5 min by the ultra-liberation and ultra-blend effects of ultrasound, therefore, the cleaning efficiency was highly improved. However, the fouling substances could not be cleaned entirely in the simple physical cleaning process by SEM analysis.

47 CFR 87.41 - Frequencies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AVIATION SERVICES... frequencies in order to minimize interference and obtain the most effective use of stations. See subpart E and... geographical areas. (c) Government frequencies. Frequencies allocated exclusively to federal government radio...

Improved extraction of avocado oil by application of sono-physical processes.

PubMed

Martínez-Padilla, Laura Patricia; Franke, Lisa; Xu, Xin-Qing; Juliano, Pablo

2018-01-01

Ultrasound treatment is known to increase the oil extractability in olive and palm oil processes. This work examined the effect of ultrasound conditioning of avocado puree on oil extractability and quality, at low (18+40kHz) and high (2MHz) frequencies, at litre-scale. Other ultrasound parameters evaluated included high frequency effect (0.4, 0.6, and 2MHz; 5min; 90kJ/kg) and sonication time (2.5-10min at 2MHz), without malaxation. Finally, a megasonic post-malaxation intervention was assessed at selected malaxation times (15, 30, and 60min). Both low and high frequency ultrasound treatments of the non-malaxed avocado puree improved extractability by 15-24% additional oil recovery, with the highest extractability achieved after 2MHz treatments, depending on the fruit maturity and oil content. There was no preferential improvement on oil extractability observed across high frequencies, even though extractability increased with sonication time. Ultrasound treatment also showed a positive effect after puree malaxation. Oils obtained from sonicated purees showed peroxide and free fatty acid values below the industrial specification levels and an increase in total phenolic compounds after 2MHz treatment. High frequency ultrasound conditioning of avocado puree can enhance oil separation and potentially decrease the malaxation time in industrial processes without impacting on oil quality. Copyright © 2017 Elsevier B.V. All rights reserved.

Dual-frequency ultrasound for detecting and sizing bubbles.

PubMed

Buckey, Jay C; Knaus, Darin A; Alvarenga, Donna L; Kenton, Marc A; Magari, Patrick J

2005-01-01

ISS construction and Mars exploration require extensive extravehicular activity (EVA), exposing crewmembers to increased decompression sickness risk. Improved bubble detection technologies could help increase EVA efficiency and safety. Creare Inc. has developed a bubble detection and sizing instrument using dual-frequency ultrasound. The device emits "pump" and "image" signals at two frequencies. The low-frequency pump signal causes an appropriately-sized bubble to resonate. When the image frequency hits a resonating bubble, mixing signals are returned at the sum and difference of the two frequencies. To test the feasibility of transcutaneous intravascular detection, intravascular bubbles in anesthetized swine were produced using agitated saline and decompression stress. Ultrasonic transducers on the chest provided the two frequencies. Mixing signals were detected transthoracically in the right atrium using both methods. A histogram of estimated bubble sizes could be constructed. Bubbles can be detected and sized transthoracically in the right atrium using dual-frequency ultrasound. c2005 Elsevier Ltd. All rights reserved.

Electro-optic Q-switch

NASA Technical Reports Server (NTRS)

Zou, Yingyin (Inventor); Chen, Qiushui (Inventor); Zhang, Run (Inventor); Jiang, Hua (Inventor)

2006-01-01

An electro-optic Q-switch for generating sequence of laser pulses was disclosed. The Q-switch comprises a quadratic electro-optic material and is connected with an electronic unit generating a radio frequency wave with positive and negative pulses alternatively. The Q-switch is controlled by the radio frequency wave in such a way that laser pulse is generated when the radio frequency wave changes its polarity.

Electromagnetic Propagation Problems in the Tactical Environment

DTIC Science & Technology

1982-04-01

Radio Consultative Committee of the International Telecommunications Union , Geneva 1-9 Table I Frequency Ranges Frequency Band Typical Tactical... Union , Geneva, 1978. 4. Bradley, P. A., AGARD Lecture Series No. 99, Propagation at medium and high frequencies: Practical radio systems and...International Radio Consultative Committee, Antenna Diagrams, International Telecommunication Union , Geneva, 1978. 7. Barghausen, A. F., J. W. Finney, L. L

Ultrasound assisted biogas production from landfill leachate

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oz, Nilgün Ayman, E-mail: nilgunayman@comu.edu.tr; Yarimtepe, Canan Can

Highlights: • Effect of low frequency ultrasound pretreatment on leachate was investigated. • Three different ultrasound energy inputs (200, 400 and 600 W/l) was applied. • Low-frequency ultrasound treatment increased soluble COD in landfill leachate. • Application of ultrasound to leachate increased biogas production about 40%. • Application of ultrasound to leachate increased total methane production rate about 20%. - Abstract: The aim of this study is to increase biogas production and methane yield from landfill leachate in anaerobic batch reactors by using low frequency ultrasound as a pretreatment step. In the first part of the study, optimum conditions formore » solubilization of organic matter in leachate samples were investigated using various sonication durations at an ultrasound frequency of 20 kHz. The level of organic matter solubilization during ultrasonic pretreatment experiments was determined by calculating the ratio of soluble chemical oxygen demand (sCOD) to total chemical oxygen demand (tCOD). The sCOD/tCOD ratio was increased from 47% in raw leachate to 63% after 45 min sonication at 600 W/l. Non-parametric Friedman’s test indicated that ultrasonic pretreatment has a significant effect on sCOD parameter for leachate (p < 0.05). In the second part of the study, anaerobic batch reactors were operated for both ultrasonically pretreated and untreated landfill leachate samples in order to assess the effect of sonication on biogas and methane production rate. In anaerobic batch reactor feed with ultrasonically pretreated leachate, 40% more biogas was obtained compared to the control reactor. For statistical analysis, Mann–Whitney U test was performed to compare biogas and methane production rates for raw and pretreated leachate samples and it has been found that ultrasonic pretreatment significantly enhanced biogas and methane production rates from leachate (p < 0.05) in anaerobic batch reactors. The overall results showed that low frequency ultrasound pretreatment can be potentially used for wastewater management especially with integration of anaerobic processes.« less

Development of paper-based wireless communication modules for point-of-care diagnostic applications

NASA Astrophysics Data System (ADS)

Smith, Suzanne; Bezuidenhout, Petroné H.; Land, Kevin; Korvink, Jan G.; Mager, Dario

2016-02-01

We present an ultra-high frequency radio frequency identification based wireless communication set-up for paper-based point-of-care diagnostic applications, based on a sensing radio frequency identification chip. Paper provides a low-cost, disposable platform for ease of fluidic handling without bulky instrumentation, and is thus ideally suited for point-ofcare applications; however, result communication - a crucial aspect for healthcare to be implemented effectively - is still lacking. Printing of radio frequency identification antennas and electronic circuitry for sensing on paper are presented, with read out of the results using a radio frequency identification reader illustrated, demonstrating the feasibility of developing integrated, all-printed solutions for point-of-care diagnosis in resource-limited settings.

Method for high resolution magnetic resonance analysis using magic angle technique

DOEpatents

Wind, Robert A.; Hu, Jian Zhi

2003-11-25

A method of performing a magnetic resonance analysis of a biological object that includes placing the biological object in a main magnetic field and in a radio frequency field, the main magnetic field having a static field direction; rotating the biological object at a rotational frequency of less than about 100 Hz around an axis positioned at an angle of about 54.degree.44' relative to the main magnetic static field direction; pulsing the radio frequency to provide a sequence that includes a magic angle turning pulse segment; and collecting data generated by the pulsed radio frequency. According to another embodiment, the radio frequency is pulsed to provide a sequence capable of producing a spectrum that is substantially free of spinning sideband peaks.

47 CFR 95.1113 - Frequency coordinator.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PERSONAL RADIO SERVICES Wireless Medical Telemetry Service (WMTS) General Provisions § 95.1113 Frequency coordinator. (a... with radio astronomy observatories and Federal Government radar systems as specified in §§ 95.1119 and...

47 CFR 95.1113 - Frequency coordinator.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PERSONAL RADIO SERVICES Wireless Medical Telemetry Service (WMTS) General Provisions § 95.1113 Frequency coordinator. (a... with radio astronomy observatories and Federal Government radar systems as specified in §§ 95.1119 and...

DEMONSTRATION BULLETIN: RADIO FREQUENCY HEATING - IIT RESEARCH INSTITUTE

EPA Science Inventory

Radio frequency heating (RFH) is a process that uses electromagnetic energy generated by radio waves to heat soil in situ, thereby potentially enhancing the performance of standard soil vapor extraction (SVE) technologies. An RFH system developed by the IIT Research Institute ...

47 CFR 2.801 - Radiofrequency device defined.

Code of Federal Regulations, 2011 CFR

2011-10-01

....801 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL FREQUENCY ALLOCATIONS AND RADIO TREATY MATTERS; GENERAL RULES AND REGULATIONS Marketing of Radio-frequency Devices § 2.801 Radiofrequency device..., but are not limited to: (a) The various types of radio communication transmitting devices described...

WE-EF-210-07: Development of a Minimally Invasive Photo Acoustic Imaging System for Early Prostate Cancer Detection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sano, M; Yousefi, S; Xing, L

Purpose: The objective of this work is to design, implement and characterize a catheter-based ultrasound/photoacoustic imaging probe for early-diagnosis of prostate cancer and to aid in image-guided radiation therapy. Methods: The need to image across 6–10cm of tissue to image the whole prostate gland limits the resolution achievable with a transrectal ultrasound approach. In contrast, the urethra bisects the prostate gland, providing a minimally invasive pathway for deploying a high resolution ultrasound transducer. Utilizing a high-frequency (20MHz) ultrasound/photoacoustic probe, high-resolution structural and molecular imaging of the prostate tissue is possible. A custom 3D printed probe containing a high-frequency single-element ultrasoundmore » transducer is utilized. The diameter of the probe is designed to fit inside a Foley catheter and the probe is rotated around the central axis to achieve a circular B-scan. A custom ultrasound amplifier and receiver was set up to trigger the ultrasound pulse transmission and record the reflected signal. The reconstructed images were compared to images generated by traditional 5 MHz ultrasound transducers. Results: The preliminary results using the high-frequency ultrasound probe show that it is possible to resolve finely detailed information in a prostate tissue phantom that was not achievable with previous low-frequency ultrasound systems. Preliminary ultrasound imaging was performed on tissue mimicking phantom and sensitivity and signal-to-noise ratio of the catheter was measured. Conclusion: In order to achieve non-invasive, high-resolution, structural and molecular imaging for early-diagnosis and image-guided radiation therapy of the prostate tissue, a transurethral catheter was designed. Structural/molecular imaging using ultrasound/photoacoustic of the prostate tissue will allow for localization of hyper vascularized areas for early-stage prostate cancer diagnosis.« less

Wide band stepped frequency ground penetrating radar

DOEpatents

Bashforth, Michael B.; Gardner, Duane; Patrick, Douglas; Lewallen, Tricia A.; Nammath, Sharyn R.; Painter, Kelly D.; Vadnais, Kenneth G.

1996-01-01

A wide band ground penetrating radar system (10) embodying a method wherein a series of radio frequency signals (60) is produced by a single radio frequency source (16) and provided to a transmit antenna (26) for transmission to a target (54) and reflection therefrom to a receive antenna (28). A phase modulator (18) modulates those portion of the radio frequency signals (62) to be transmitted and the reflected modulated signal (62) is combined in a mixer (34) with the original radio frequency signal (60) to produce a resultant signal (53) which is demodulated to produce a series of direct current voltage signals (66) the envelope of which forms a cosine wave shaped plot (68) which is processed by a Fast Fourier Transform unit 44 into frequency domain data (70) wherein the position of a preponderant frequency is indicative of distance to the target (54) and magnitude is indicative of the signature of the target (54).

Radiosurgical fistulotomy; an alternative to conventional procedure in fistula in ano.

PubMed

Gupta, Pravin J

2003-01-01

Most surgeons continue to prefer the classic lay open technique [fistulotomy] as the gold standard of treatment in anal fistula. In this randomized study, a comparison is made between conventional fistulotomy and fistulotomy performed by a radio frequency device. One hundred patients of low anal fistula posted for fistulotomy were randomized prospectively to either a conventional or radio frequency technique. Parameters measured included time taken for the procedure, amount of blood loss, postoperative pain, return to work, and recurrence rate. The patient demographic was comparable in 2 groups. The radio frequency fistulotomy was quicker as compared to a conventional one [22 versus 37 minutes, p = 0.001], amount of bleeding was significantly less [47 ml versus 134 ml, p = 0.002], and hospital stay was less when patient was operated by radio frequency method [37 hours versus 56 hours in conventional method, p = 0.001]. The postoperative pain in the first 24 hours was more in conventional group [2 to 5 versus 0 to 3 on visual analogue scale]. The patients from radio frequency group resumed their duties early with a reduced healing period of the wounds [47 versus 64 days, p = 0.01]. The recurrence or failure rates were comparable in the radio frequency and conventional groups [2% versus 6%]. Fistulotomy procedure using a radio frequency technique has significant advantages over a conventional procedure with regard to operation time, blood loss, return to normal activity, and healing time of the wound.

[Clinical auxiliary diagnosis value of high frequency ultrasonographic measurements of the thickness of transverse carpal ligaments in carpal tunnel syndrome patients].

PubMed

Xu, L; Chen, F M; Wang, L; Zhang, P X; Jiang, X R

2016-04-18

To evaluate the meaning and value of high-frequency ultrasound in the diagnosis of carpal tunnel syndrome (CTS). In this study, 48 patients (unilateral hand) with CTS were analyzed. The thickness of transverse carpal ligaments at the pisiform bone was measured using high-frequency ultrasound. Open carpal tunnel release procedure was performed in the 48 CTS patients, and the thickness of transverse carpal ligaments at the hamate hook bone measured using vernier caliper under direct vision. The accuracy of thickness of transverse carpal ligaments was evaluated using high-frequency ultrasound. high-frequency ultrasound measurement of thickness of transverse carpal ligaments at the hamate hook bone and pisiform bone, and determination of the diagnostic threshold measurement index using receiver operating characteristic (ROC) curve, sensitivity and specificity were performed and the correlation between the thickness of transverse carpal ligaments and nerve conduction study (NCS) analyzed. The thickness of transverse carpal ligaments in the CTS patients were (0.42±0.08) cm (high-frequency ultrasound) and (0.41±0.06) cm (operation) at hamate hook bone, and there was no significant difference between the two ways (t=0.672, P>0.05). The optimal cut-off value of the transverse carpal ligaments at hamate hook bone was 0.385 cm, the sensitivity 0.775, and the specificity 0.788. The optimal cut-off value of the transverse carpal ligaments at the pisiform bone was 0.315 cm, the sensitivity 0.950, and the specificity 1.000. The transverse carpal ligaments thickness and wrist-index finger sensory nerve conduction velocity (SCV), wrist-middle finger SCV showed a negative correlation. High frequency ultrasound measurements of thickness of transverse carpal ligaments is a valuable method for the diagnosis of CTS.

MULTI-MESSENGER ASTRONOMY OF GRAVITATIONAL-WAVE SOURCES WITH FLEXIBLE WIDE-AREA RADIO TRANSIENT SURVEYS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yancey, Cregg C.; Shawhan, Peter; Bear, Brandon E.

We explore opportunities for multi-messenger astronomy using gravitational waves (GWs) and prompt, transient low-frequency radio emission to study highly energetic astrophysical events. We review the literature on possible sources of correlated emission of GWs and radio transients, highlighting proposed mechanisms that lead to a short-duration, high-flux radio pulse originating from the merger of two neutron stars or from a superconducting cosmic string cusp. We discuss the detection prospects for each of these mechanisms by low-frequency dipole array instruments such as LWA1, the Low Frequency Array and the Murchison Widefield Array. We find that a broad range of models may bemore » tested by searching for radio pulses that, when de-dispersed, are temporally and spatially coincident with a LIGO/Virgo GW trigger within a ∼30 s time window and ∼200–500 deg{sup 2} sky region. We consider various possible observing strategies and discuss their advantages and disadvantages. Uniquely, for low-frequency radio arrays, dispersion can delay the radio pulse until after low-latency GW data analysis has identified and reported an event candidate, enabling a prompt radio signal to be captured by a deliberately targeted beam. If neutron star mergers do have detectable prompt radio emissions, a coincident search with the GW detector network and low-frequency radio arrays could increase the LIGO/Virgo effective search volume by up to a factor of ∼2. For some models, we also map the parameter space that may be constrained by non-detections.« less

LOFAR/H-ATLAS: the low-frequency radio luminosity-star formation rate relation

NASA Astrophysics Data System (ADS)

Gürkan, G.; Hardcastle, M. J.; Smith, D. J. B.; Best, P. N.; Bourne, N.; Calistro-Rivera, G.; Heald, G.; Jarvis, M. J.; Prandoni, I.; Röttgering, H. J. A.; Sabater, J.; Shimwell, T.; Tasse, C.; Williams, W. L.

2018-04-01

Radio emission is a key indicator of star formation activity in galaxies, but the radio luminosity-star formation relation has to date been studied almost exclusively at frequencies of 1.4 GHz or above. At lower radio frequencies, the effects of thermal radio emission are greatly reduced, and so we would expect the radio emission observed to be completely dominated by synchrotron radiation from supernova-generated cosmic rays. As part of the LOFAR Surveys Key Science project, the Herschel-ATLAS NGP field has been surveyed with LOFAR at an effective frequency of 150 MHz. We select a sample from the MPA-JHU catalogue of Sloan Digital Sky Survey galaxies in this area: the combination of Herschel, optical and mid-infrared data enable us to derive star formation rates (SFRs) for our sources using spectral energy distribution fitting, allowing a detailed study of the low-frequency radio luminosity-star formation relation in the nearby Universe. For those objects selected as star-forming galaxies (SFGs) using optical emission line diagnostics, we find a tight relationship between the 150 MHz radio luminosity (L150) and SFR. Interestingly, we find that a single power-law relationship between L150 and SFR is not a good description of all SFGs: a broken power-law model provides a better fit. This may indicate an additional mechanism for the generation of radio-emitting cosmic rays. Also, at given SFR, the radio luminosity depends on the stellar mass of the galaxy. Objects that were not classified as SFGs have higher 150-MHz radio luminosity than would be expected given their SFR, implying an important role for low-level active galactic nucleus activity.

Clinical combination of multiphoton tomography and high frequency ultrasound imaging for evaluation of skin diseases

NASA Astrophysics Data System (ADS)

König, K.; Speicher, M.; Koehler, M. J.; Scharenberg, R.; Elsner, P.; Kaatz, M.

2010-02-01

For the first time, high frequency ultrasound imaging, multiphoton tomography, and dermoscopy were combined in a clinical study. Different dermatoses such as benign and malign skin cancers, connective tissue diseases, inflammatory skin diseases and autoimmune bullous skin diseases have been investigated with (i) state-of-the-art and highly sophisticated ultrasound systems for dermatology, (ii) the femtosecond-laser multiphoton tomograph DermaInspectTM and (iii) dermoscopes. Dermoscopy provides two-dimensional color imaging of the skin surface with a magnification up to 70x. Ultrasound images are generated from reflections of the emitted ultrasound signal, based on inhomogeneities of the tissue. These echoes are converted to electrical signals. Depending on the ultrasound frequency the penetration depth varies from about 1 mm to 16 mm in dermatological application. The 100-MHz-ultrasound system provided an axial resolution down to 16 μm and a lateral resolution down to 32 μm. In contrast to the wide-field ultrasound images, multiphoton tomography provided horizontal optical sections of 0.36×0.36 mm2 down to 200 μm tissue depth with submicron resolution. The autofluorescence of mitochondrial coenzymes, melanin, and elastin as well as the secondharmonic- generation signal of the collagen network were imaged. The combination of ultrasound and multiphoton tomography provides a novel opportunity for diagnostics of skin disorders.

High-frequency ultrasound imaging for breast cancer biopsy guidance

PubMed Central

Cummins, Thomas; Yoon, Changhan; Choi, Hojong; Eliahoo, Payam; Kim, Hyung Ham; Yamashita, Mary W.; Hovanessian-Larsen, Linda J.; Lang, Julie E.; Sener, Stephen F.; Vallone, John; Martin, Sue E.; Kirk Shung, K.

2015-01-01

Abstract. Image-guided core needle biopsy is the current gold standard for breast cancer diagnosis. Microcalcifications, an important radiographic finding on mammography suggestive of early breast cancer such as ductal carcinoma in situ, are usually biopsied under stereotactic guidance. This procedure, however, is uncomfortable for patients and requires the use of ionizing radiation. It would be preferable to biopsy microcalcifications under ultrasound guidance since it is a faster procedure, more comfortable for the patient, and requires no radiation. However, microcalcifications cannot reliably be detected with the current standard ultrasound imaging systems. This study is motivated by the clinical need for real-time high-resolution ultrasound imaging of microcalcifications, so that biopsies can be accurately performed under ultrasound guidance. We have investigated how high-frequency ultrasound imaging can enable visualization of microstructures in ex vivo breast tissue biopsy samples. We generated B-mode images of breast tissue and applied the Nakagami filtering technique to help refine image output so that microcalcifications could be better assessed during ultrasound-guided core biopsies. We describe the preliminary clinical results of high-frequency ultrasound imaging of ex vivo breast biopsy tissue with microcalcifications and without Nakagami filtering and the correlation of these images with the pathology examination by hematoxylin and eosin stain and whole slide digital scanning. PMID:26693167

Solar observations with a low frequency radio telescope

NASA Astrophysics Data System (ADS)

Myserlis, I.; Seiradakis, J.; Dogramatzidis, M.

2012-01-01

We have set up a low frequency radio monitoring station for solar bursts at the Observatory of the Aristotle University in Thessaloniki. The station consists of a dual dipole phased array, a radio receiver and a dedicated computer with the necessary software installed. The constructed radio receiver is based on NASA's Radio Jove project. It operates continuously, since July 2010, at 20.1 MHz (close to the long-wavelength ionospheric cut-off of the radio window) with a narrow bandwidth (~5 kHz). The system is properly calibrated, so that the recorded data are expressed in antenna temperature. Despite the high interference level of an urban region like Thessaloniki (strong broadcasting shortwave radio stations, periodic experimental signals, CBs, etc), we have detected several low frequency solar radio bursts and correlated them with solar flares, X-ray events and other low frequency solar observations. The received signal is monitored in ordinary ASCII format and as audio signal, in order to investigate and exclude man-made radio interference. In order to exclude narrow band interference and calculate the spectral indices of the observed events, a second monitoring station, working at 36 MHz, is under construction at the village of Nikiforos near the town of Drama, about 130 km away of Thessaloniki. Finally, we plan to construct a third monitoring station at 58 MHz, in Thessaloniki. This frequency was revealed to be relatively free of interference, after a thorough investigation of the region.

Dual-frequency ultrasound focal therapy for MRI-guided transurethral treatment of the prostate: Study in gel phantom

NASA Astrophysics Data System (ADS)

N'Djin, W. Apoutou; Mougenot, Charles; Kobelevskiy, Ilya; Ramsay, Elizabeth; Bronskill, Michael; Chopra, Rajiv

2012-11-01

Ultrasound thermal therapy of localized prostate cancer offers a minimally-invasive non-ionizing alternative [1-3] to surgery and radiotherapy. MRI-controlled transurethral ultrasound prostate therapy [4-6] has previously been investigated in a pilot human feasibility study [7], by treating a small sub-volume of prostate tissue. In this study, the feasibility of transurethral dual-frequency ultrasound focal therapy has been investigated in gel phantom. A database of pelvic anatomical models of human prostate cancer patients have been created using MR clinical images. The largest prostate boundary (47 cm3) was used to fabricate an anatomical gel phantom which included various MR characteristics to mimic prostate tissues, 4 localized tumors and surrounding prostate tissues. A 9-element transurethral ultrasound applicator working in dual-frequency mode (f = 4.6/14.5 MHz) was evaluated to heat: (i) the entire prostate volume (Full prostate treatment strategy), (ii) a prostate region restricted to tumors (Focal therapy). Acoustic power of each element and rotation rate of the device were adjusted in realtime based on MR-thermometry feedback control (nine thermal slices updated every 6.2s). Experiments have been performed using dual-frequency ultrasound exposures (surface Pmax: 20W.cm-2). (i) For full prostate heating, 7 elements of the device were used to cover the entire prostate length. The heating process was completed within 35 min. Ultrasound exposures at the fundamental frequency allowed full heating of the largest prostate radii (>18 mm), while exposures at the 3rd harmonic ensured homogeneous treatment of the smallest radii. Undertreated and overtreated regions represented respectively 2% and 17% of the prostate volume. (ii) For focal therapy, the target region was optimized to maintain safe regions in the prostate and to cover all tumor-mimics. Only 5 ultrasound elements were used to treat successfully all tumor-mimics within 26 min. Undertreated and overtreated regions each represented 7% of the prostate volume. MRI-guided transurethral ultrasound procedure enables full treatment and focal therapy in human prostate geometry. Prostate volume heating was fast compared to standard HIFU prostate treatments. Dual-frequency ultrasound exposures allowed optimal heat deposition in all prostate regions. The focal therapy strategy is promising as regard to safety and could contribute to enhance the post-treatment autonomy of the patient.

Effect of ultrasound frequency on the Nakagami statistics of human liver tissues.

PubMed

Tsui, Po-Hsiang; Zhou, Zhuhuang; Lin, Ying-Hsiu; Hung, Chieh-Ming; Chung, Shih-Jou; Wan, Yung-Liang

2017-01-01

The analysis of the backscattered statistics using the Nakagami parameter is an emerging ultrasound technique for assessing hepatic steatosis and fibrosis. Previous studies indicated that the echo amplitude distribution of a normal liver follows the Rayleigh distribution (the Nakagami parameter m is close to 1). However, using different frequencies may change the backscattered statistics of normal livers. This study explored the frequency dependence of the backscattered statistics in human livers and then discussed the sources of ultrasound scattering in the liver. A total of 30 healthy participants were enrolled to undergo a standard care ultrasound examination on the liver, which is a natural model containing diffuse and coherent scatterers. The liver of each volunteer was scanned from the right intercostal view to obtain image raw data at different central frequencies ranging from 2 to 3.5 MHz. Phantoms with diffuse scatterers only were also made to perform ultrasound scanning using the same protocol for comparisons with clinical data. The Nakagami parameter-frequency correlation was evaluated using Pearson correlation analysis. The median and interquartile range of the Nakagami parameter obtained from livers was 1.00 (0.98-1.05) for 2 MHz, 0.93 (0.89-0.98) for 2.3 MHz, 0.87 (0.84-0.92) for 2.5 MHz, 0.82 (0.77-0.88) for 3.3 MHz, and 0.81 (0.76-0.88) for 3.5 MHz. The Nakagami parameter decreased with the increasing central frequency (r = -0.67, p < 0.0001). However, the effect of ultrasound frequency on the statistical distribution of the backscattered envelopes was not found in the phantom results (r = -0.147, p = 0.0727). The current results demonstrated that the backscattered statistics of normal livers is frequency-dependent. Moreover, the coherent scatterers may be the primary factor to dominate the frequency dependence of the backscattered statistics in a liver.

Stable radio frequency dissemination by simple hybrid frequency modulation scheme.

PubMed

Yu, Longqiang; Wang, Rong; Lu, Lin; Zhu, Yong; Wu, Chuanxin; Zhang, Baofu; Wang, Peizhang

2014-09-15

In this Letter, we propose a fiber-based stable radio frequency transfer system by a hybrid frequency modulation scheme. Creatively, two radio frequency signals are combined and simultaneously transferred by only one laser diode. One frequency component is used to detect the phase fluctuation, and the other one is the derivative compensated signal providing a stable frequency for the remote end. A proper ratio of the frequencies of the components is well maintained by parameter m to avoid interference between them. Experimentally, a stable 200 MHz signal is transferred over 100 km optical fiber with the help of a 1 GHz detecting signal, and fractional instability of 2×10(-17) at 10(5) s is achieved.

OMEGA SYSTEM SYNCHRONIZATION.

DTIC Science & Technology

TIME SIGNALS, * SYNCHRONIZATION (ELECTRONICS)), NETWORKS, FREQUENCY, STANDARDS, RADIO SIGNALS, ERRORS, VERY LOW FREQUENCY, PROPAGATION, ACCURACY, ATOMIC CLOCKS, CESIUM, RADIO STATIONS, NAVAL SHORE FACILITIES

47 CFR Appendix 1 to Subpart E of... - Glossary of Terms

Code of Federal Regulations, 2010 CFR

2010-10-01

... which also typically includes a frequency monitoring system that initiates a MedRadio communications... Part 95 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO... station authorized in the CB. Channel frequencies. Reference frequencies from which the carrier frequency...

47 CFR Appendix 1 to Subpart E of... - Glossary of Terms

Code of Federal Regulations, 2011 CFR

2011-10-01

... which also typically includes a frequency monitoring system that initiates a MedRadio communications... Part 95 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO... station authorized in the CB. Channel frequencies. Reference frequencies from which the carrier frequency...

Multifrequency ultrasound transducers for conformal interstitial thermal therapy.

PubMed

Chopra, Rajiv; Luginbuhl, Chris; Foster, F Stuart; Bronskill, Michael J

2003-07-01

Control over the pattern of thermal damage generated by interstitial ultrasound heating applicators can be enhanced by changing the ultrasound frequency during heating. The ability to change transmission frequency from a single transducer through the use of high impedance front layers was investigated in this study. The transmission spectrum of multifrequency transducers was calculated using the KLM equivalent circuit model and verified with experimental measurements on prototype transducers. The addition of a quarter-wavelength thick PZT (unpoled) front layer enabled the transmission of ultrasound at two discrete frequencies, 4.7 and 9.7 MHz, from a transducer with an original resonant frequency of 8.4 MHz. Three frequency transmission at 3.3, 8.4, and 10.8 MHz was possible for a transducer with a half-wavelength thick front layer. Calculations of the predicted thermal lesion size at each transmission frequency indicated that the depth of thermal lesion could be varied by a factor of 1.6 for the quarter-wavelength front layer. Heating experiments performed in excised liver tissue with a dual-frequency applicator confirmed this ability to control the shape of thermal lesions during heating to generate a desired geometry. Practical interstitial designs that enable the generation of shaped thermal lesions are feasible.

47 CFR 15.105 - Information to the user.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL RADIO FREQUENCY DEVICES Unintentional Radiators § 15.105... generates, uses, and can radiate radio frequency energy and, if not installed and used in accordance with the instruction manual, may cause harmful interference to radio communications. Operation of this...

47 CFR 15.105 - Information to the user.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL RADIO FREQUENCY DEVICES Unintentional Radiators § 15.105... generates, uses, and can radiate radio frequency energy and, if not installed and used in accordance with the instruction manual, may cause harmful interference to radio communications. Operation of this...

47 CFR 15.105 - Information to the user.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL RADIO FREQUENCY DEVICES Unintentional Radiators § 15.105... generates, uses, and can radiate radio frequency energy and, if not installed and used in accordance with the instruction manual, may cause harmful interference to radio communications. Operation of this...

47 CFR 15.105 - Information to the user.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL RADIO FREQUENCY DEVICES Unintentional Radiators § 15.105... generates, uses, and can radiate radio frequency energy and, if not installed and used in accordance with the instruction manual, may cause harmful interference to radio communications. Operation of this...

Differences in Ultrasonic Vocalizations between Wild and Laboratory California Mice (Peromyscus californicus)

PubMed Central

Kalcounis-Rueppell, Matina C.; Petric, Radmila; Briggs, Jessica R.; Carney, Catherine; Marshall, Matthew M.; Willse, John T.; Rueppell, Olav; Ribble, David O.; Crossland, Janet P.

2010-01-01

Background Ultrasonic vocalizations (USVs) emitted by muroid rodents, including laboratory mice and rats, are used as phenotypic markers in behavioral assays and biomedical research. Interpretation of these USVs depends on understanding the significance of USV production by rodents in the wild. However, there has never been a study of muroid rodent ultrasound function in the wild and comparisons of USVs produced by wild and laboratory rodents are lacking to date. Here, we report the first comparison of wild and captive rodent USVs recorded from the same species, Peromyscus californicus. Methodology and Principal Findings We used standard ultrasound recording techniques to measure USVs from California mice in the laboratory (Peromyscus Genetic Stock Center, SC, USA) and the wild (Hastings Natural History Reserve, CA, USA). To determine which California mouse in the wild was vocalizing, we used a remote sensing method that used a 12-microphone acoustic localization array coupled with automated radio telemetry of all resident Peromyscus californicus in the area of the acoustic localization array. California mice in the laboratory and the wild produced the same types of USV motifs. However, wild California mice produced USVs that were 2–8 kHz higher in median frequency and significantly more variable in frequency than laboratory California mice. Significance The similarity in overall form of USVs from wild and laboratory California mice demonstrates that production of USVs by captive Peromyscus is not an artifact of captivity. Our study validates the widespread use of USVs in laboratory rodents as behavioral indicators but highlights that particular characteristics of laboratory USVs may not reflect natural conditions. PMID:20368980

Ultrasound indoor positioning system based on a low-power wireless sensor network providing sub-centimeter accuracy.

PubMed

Medina, Carlos; Segura, José Carlos; De la Torre, Ángel

2013-03-13

This paper describes the TELIAMADE system, a new indoor positioning system based on time-of-flight (TOF) of ultrasonic signal to estimate the distance between a receiver node and a transmitter node. TELIAMADE system consists of a set of wireless nodes equipped with a radio module for communication and a module for the transmission and reception of ultrasound. The access to the ultrasonic channel is managed by applying a synchronization algorithm based on a time-division multiplexing (TDMA) scheme. The ultrasonic signal is transmitted using a carrier frequency of 40 kHz and the TOF measurement is estimated by applying a quadrature detector to the signal obtained at the A/D converter output. Low sampling frequencies of 17.78 kHz or even 12.31 kHz are possible using quadrature sampling in order to optimize memory requirements and to reduce the computational cost in signal processing. The distance is calculated from the TOF taking into account the speed of sound. An excellent accuracy in the estimation of the TOF is achieved using parabolic interpolation to detect of maximum of the signal envelope at the matched filter output. The signal phase information is also used for enhancing the TOF measurement accuracy. Experimental results show a root mean square error (rmse) less than 2 mm and a standard deviation less than 0.3 mm for pseudorange measurements in the range of distances between 2 and 6 m. The system location accuracy is also evaluated by applying multilateration. A sub-centimeter location accuracy is achieved with an average rmse of 9.6 mm.

Spectral Energy Distribution and Radio Halo of NGC 253 at Low Radio Frequencies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kapińska, A. D.; Staveley-Smith, L.; Meurer, G. R.

We present new radio continuum observations of NGC 253 from the Murchison Widefield Array at frequencies between 76 and 227 MHz. We model the broadband radio spectral energy distribution for the total flux density of NGC 253 between 76 MHz and 11 GHz. The spectrum is best described as a sum of a central starburst and extended emission. The central component, corresponding to the inner 500 pc of the starburst region of the galaxy, is best modeled as an internally free–free absorbed synchrotron plasma, with a turnover frequency around 230 MHz. The extended emission component of the spectrum of NGCmore » 253 is best described as a synchrotron emission flattening at low radio frequencies. We find that 34% of the extended emission (outside the central starburst region) at 1 GHz becomes partially absorbed at low radio frequencies. Most of this flattening occurs in the western region of the southeast halo, and may be indicative of synchrotron self-absorption of shock-reaccelerated electrons or an intrinsic low-energy cutoff of the electron distribution. Furthermore, we detect the large-scale synchrotron radio halo of NGC 253 in our radio images. At 154–231 MHz the halo displays the well known X-shaped/horn-like structure, and extends out to ∼8 kpc in the z -direction (from the major axis).« less

Characterization of an Outdoor Ambient Radio Frequency Environment

DTIC Science & Technology

2016-02-16

radio frequency noise ”) prior to testing of a specific system under test (SUT). With this characterization, locations can be selected to avoid RF...spectrum analyzer, ambient RF noise floor, RF interference 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT SAR 18...environment (sometimes referred to as “radio frequency noise ”) prior to testing of a specific system under test (SUT). With this characterization

Radio Frequency Identification (RFID) Based Corrosion Monitoring Sensors. Part 2: Application and Testing of the Coating Materials

DTIC Science & Technology

2014-12-22

Radio frequency identification ( RFID ) based corrosion monitoring sensors: Part II Application and testing of the coating materials Youliang He1...email: yohe@nrcan.gc.ca Keywords: Corrosion monitoring; Wireless sensor; RFID ; Electromagnetic interference; Coating. Abstract Cost-effective...Radio Frequency Identification ( RFID ) transponders (tags) were investigated for wireless corrosion monitoring by applying a metal-filled conductive

Technique for Predicting the Radio Frequency Field Strength Inside an Enclosure

NASA Technical Reports Server (NTRS)

Hallett, Michael P.; Reddell, Jerry P.

1997-01-01

This technical memo represents a simple analytical technique for predicting the Radio Frequency (RF) field inside an enclosed volume in which radio frequency occurs. The technique was developed to predict the RF field strength within a launch vehicle fairing in which some payloads desire to launch with their telemetry transmitter radiating. This technique considers both the launch vehicle and the payload aspects.

Manipulation of Microbubble Clusters Using Focused Ultrasound

NASA Astrophysics Data System (ADS)

Matsuzaki, Hironobu; Osaki, Taichi; Kawaguchi, Kei; Unga, Johan; Ichiyanagi, Mitsuhisa; Azuma, Takashi; Suzuki, Ryo; Maruyama, Kazuo; Takagi, Shu

2017-11-01

In recent years, microbubbles (MBs) are expected to be utilized for the ultrasound drug delivery system (DDS). For the MB-DDS, it is important to establish a method of controlling bubbles and bubble clusters using ultrasound field. The objective of this study is to clarify behaviors of bubble clusters with various physical conditions. MBs in the ultrasound field are subjected to the primary Bjerknes force. The force traps MBs at the focal region of the focused ultrasound field. The trapped MBs form a bubble cluster at the region. A bubble cluster continues growing with absorbing surrounding bubbles until it reaches a maximum size beyond which it disappears from the focal region. In the present study, two kinds of MBs are used for the experiment. One is Sonazoid with average diameter of 2.6 um and resonant frequency of 5 MHz. The other is developed by Teikyo Univ., with average diameter of 1.5 um and presumed resonant frequency of 4 MHz. The bubble cluster's behaviors are analyzed using the high-speed camera. Sonazoid clusters have larger critical size than the other in every frequency, and its cluster size is inversely proportional to the ultrasound frequency, while Teikyo-bubble clusters have different tendency. These results are discussed in the presentation.

Radio-science performance analysis software

NASA Astrophysics Data System (ADS)

Morabito, D. D.; Asmar, S. W.

1995-02-01

The Radio Science Systems Group (RSSG) provides various support functions for several flight project radio-science teams. Among these support functions are uplink and sequence planning, real-time operations monitoring and support, data validation, archiving and distribution functions, and data processing and analysis. This article describes the support functions that encompass radio-science data performance analysis. The primary tool used by the RSSG to fulfill this support function is the STBLTY program set. STBLTY is used to reconstruct observable frequencies and calculate model frequencies, frequency residuals, frequency stability in terms of Allan deviation, reconstructed phase, frequency and phase power spectral density, and frequency drift rates. In the case of one-way data, using an ultrastable oscillator (USO) as a frequency reference, the program set computes the spacecraft transmitted frequency and maintains a database containing the in-flight history of the USO measurements. The program set also produces graphical displays. Some examples and discussions on operating the program set on Galileo and Ulysses data will be presented.

Radio-Science Performance Analysis Software

NASA Astrophysics Data System (ADS)

Morabito, D. D.; Asmar, S. W.

1994-10-01

The Radio Science Systems Group (RSSG) provides various support functions for several flight project radio-science teams. Among these support functions are uplink and sequence planning, real-time operations monitoring and support, data validation, archiving and distribution functions, and data processing and analysis. This article describes the support functions that encompass radio science data performance analysis. The primary tool used by the RSSG to fulfill this support function is the STBLTY program set. STBLTY is used to reconstruct observable frequencies and calculate model frequencies, frequency residuals, frequency stability in terms of Allan deviation, reconstructed phase, frequency and phase power spectral density, and frequency drift rates. In the case of one-way data, using an ultrastable oscillator (USO) as a frequency reference, the program set computes the spacecraft transmitted frequency and maintains a database containing the in-flight history of the USO measurements. The program set also produces graphical displays. Some examples and discussion on operating the program set on Galileo and Ulysses data will be presented.

Radio-science performance analysis software

NASA Technical Reports Server (NTRS)

Morabito, D. D.; Asmar, S. W.

1995-01-01

The Radio Science Systems Group (RSSG) provides various support functions for several flight project radio-science teams. Among these support functions are uplink and sequence planning, real-time operations monitoring and support, data validation, archiving and distribution functions, and data processing and analysis. This article describes the support functions that encompass radio-science data performance analysis. The primary tool used by the RSSG to fulfill this support function is the STBLTY program set. STBLTY is used to reconstruct observable frequencies and calculate model frequencies, frequency residuals, frequency stability in terms of Allan deviation, reconstructed phase, frequency and phase power spectral density, and frequency drift rates. In the case of one-way data, using an ultrastable oscillator (USO) as a frequency reference, the program set computes the spacecraft transmitted frequency and maintains a database containing the in-flight history of the USO measurements. The program set also produces graphical displays. Some examples and discussions on operating the program set on Galileo and Ulysses data will be presented.

Observing Solar Radio Bursts from the Lunar Surface

NASA Technical Reports Server (NTRS)

MacDowall, R. J.; Gopalswamy, N.; Kaiser, M. L.; Lazio, T. J.; Jones, D. L.; Bale, S. D.; Burns, J.; Kasper, J. C.; Weiler, K. W.

2011-01-01

Locating low frequency radio observatories on the lunar surface has a number of advantages, including fixes locations for the antennas and no terrestrial interference on the far side of the moon. Here, we describe the Radio Observatory for Lunar Sortie Science (ROLSS), a concept for a low frequency, radio imaging interferometric array designed to study particle acceleration in the corona and inner heliosphere. ROLSS would be deployed during an early lunar sortie or by a robotic rover as part of an unmanned landing. The prime science mission is to image type II and type III solar radio bursts with the aim of determining the sites at and mechanisms by which the radiating particles are accelerated. Secondary science goals include constraining the density of the lunar ionosphere by searching for a low radio frequency cutoff of the solar radio emissions and constraining the low energy electron population in astrophysical sources. Furthermore, ROLSS serves a pathfinder function for larger lunar radio arrays designed for faint sources.

Planck intermediate results: XLV. Radio spectra of northern extragalactic radio sources

DOE PAGES

Ade, P. A. R.; Aghanim, N.; Aller, H. D.; ...

2016-12-12

Continuum spectra covering centimetre to submillimetre wavelengths are presented in this paper for a northern sample of 104 extragalactic radio sources, mainly active galactic nuclei, based on four-epoch Planck data. The nine Planck frequencies, from 30 to 857 GHz, are complemented by a set of simultaneous ground-based radio observations between 1.1 and 37 GHz. The single-survey Planck data confirm that the flattest high-frequency radio spectral indices are close to zero, indicating that the original accelerated electron energy spectrum is much harder than commonly thought, with power-law index around 1.5 instead of the canonical 2.5. The radio spectra peak at highmore » frequencies and exhibit a variety of shapes. For a small set of low-z sources, we find a spectral upturn at high frequencies, indicating the presence of intrinsic cold dust. Finally, variability can generally be approximated by achromatic variations, while sources with clear signatures of evolving shocks appear to be limited to the strongest outbursts.« less

Planck intermediate results. XLV. Radio spectra of northern extragalactic radio sources

NASA Astrophysics Data System (ADS)

Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Aller, H. D.; Aller, M. F.; Arnaud, M.; Aumont, J.; Baccigalupi, C.; Banday, A. J.; Barreiro, R. B.; Bartolo, N.; Battaner, E.; Benabed, K.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bonaldi, A.; Bonavera, L.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Burigana, C.; Calabrese, E.; Catalano, A.; Chiang, H. C.; Christensen, P. R.; Clements, D. L.; Colombo, L. P. L.; Couchot, F.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Dickinson, C.; Diego, J. M.; Dole, H.; Donzelli, S.; Doré, O.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Eriksen, H. K.; Finelli, F.; Forni, O.; Frailis, M.; Fraisse, A. A.; Franceschi, E.; Galeotta, S.; Galli, S.; Ganga, K.; Giard, M.; Giraud-Héraud, Y.; Gjerløw, E.; González-Nuevo, J.; Górski, K. M.; Gruppuso, A.; Gurwell, M. A.; Hansen, F. K.; Harrison, D. L.; Henrot-Versillé, S.; Hernández-Monteagudo, C.; Hildebrandt, S. R.; Hobson, M.; Hornstrup, A.; Hovatta, T.; Hovest, W.; Huffenberger, K. M.; Hurier, G.; Jaffe, A. H.; Jaffe, T. R.; Järvelä, E.; Keihänen, E.; Keskitalo, R.; Kisner, T. S.; Kneissl, R.; Knoche, J.; Kunz, M.; Kurki-Suonio, H.; Lähteenmäki, A.; Lamarre, J.-M.; Lasenby, A.; Lattanzi, M.; Lawrence, C. R.; Leonardi, R.; Levrier, F.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; Maffei, B.; Maino, D.; Mandolesi, N.; Maris, M.; Martin, P. G.; Martínez-González, E.; Masi, S.; Matarrese, S.; Max-Moerbeck, W.; Meinhold, P. R.; Melchiorri, A.; Mennella, A.; Migliaccio, M.; Mingaliev, M.; Miville-Deschênes, M.-A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Munshi, D.; Murphy, J. A.; Nati, F.; Natoli, P.; Nieppola, E.; Noviello, F.; Novikov, D.; Novikov, I.; Pagano, L.; Pajot, F.; Paoletti, D.; Partridge, B.; Pasian, F.; Pearson, T. J.; Perdereau, O.; Perotto, L.; Pettorino, V.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Pratt, G. W.; Ramakrishnan, V.; Rastorgueva-Foi, E. A.; S Readhead, A. C.; Reinecke, M.; Remazeilles, M.; Renault, C.; Renzi, A.; Richards, J. L.; Ristorcelli, I.; Rocha, G.; Rossetti, M.; Roudier, G.; Rubiño-Martín, J. A.; Rusholme, B.; Sandri, M.; Savelainen, M.; Savini, G.; Scott, D.; Sotnikova, Y.; Stolyarov, V.; Sunyaev, R.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tammi, J.; Tauber, J. A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tornikoski, M.; Tristram, M.; Tucci, M.; Türler, M.; Valenziano, L.; Valiviita, J.; Valtaoja, E.; Van Tent, B.; Vielva, P.; Villa, F.; Wade, L. A.; Wehrle, A. E.; Wehus, I. K.; Yvon, D.; Zacchei, A.; Zonca, A.

2016-12-01

Continuum spectra covering centimetre to submillimetre wavelengths are presented for a northern sample of 104 extragalactic radio sources, mainly active galactic nuclei, based on four-epoch Planck data. The nine Planck frequencies, from 30 to 857 GHz, are complemented by a set of simultaneous ground-based radio observations between 1.1 and 37 GHz. The single-survey Planck data confirm that the flattest high-frequency radio spectral indices are close to zero, indicating that the original accelerated electron energy spectrum is much harder than commonly thought, with power-law index around 1.5 instead of the canonical 2.5. The radio spectra peak at high frequencies and exhibit a variety of shapes. For a small set of low-z sources, we find a spectral upturn at high frequencies, indicating the presence of intrinsic cold dust. Variability can generally be approximated by achromatic variations, while sources with clear signatures of evolving shocks appear to be limited to the strongest outbursts.

Planck intermediate results: XLV. Radio spectra of northern extragalactic radio sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ade, P. A. R.; Aghanim, N.; Aller, H. D.

Continuum spectra covering centimetre to submillimetre wavelengths are presented in this paper for a northern sample of 104 extragalactic radio sources, mainly active galactic nuclei, based on four-epoch Planck data. The nine Planck frequencies, from 30 to 857 GHz, are complemented by a set of simultaneous ground-based radio observations between 1.1 and 37 GHz. The single-survey Planck data confirm that the flattest high-frequency radio spectral indices are close to zero, indicating that the original accelerated electron energy spectrum is much harder than commonly thought, with power-law index around 1.5 instead of the canonical 2.5. The radio spectra peak at highmore » frequencies and exhibit a variety of shapes. For a small set of low-z sources, we find a spectral upturn at high frequencies, indicating the presence of intrinsic cold dust. Finally, variability can generally be approximated by achromatic variations, while sources with clear signatures of evolving shocks appear to be limited to the strongest outbursts.« less

Noncontact modal analysis of a pipe organ reed using airborne ultrasound stimulated vibrometry.

PubMed

Huber, Thomas M; Fatemi, Mostafa; Kinnick, Randy; Greenleaf, James

2006-04-01

The goal of this study was to excite and measure, in a noncontact manner, the vibrational modes of the reed from a reed organ pipe. To perform ultrasound stimulated excitation, the audio-range difference frequency between a pair of ultrasound beams produced a radiation force that induced vibrations. The resulting vibrational deflection shapes were measured with a scanning laser vibrometer. The resonances of any relatively small object can be studied in air using this technique. For a 36 mm x 6 mm brass reed, displacements and velocities in excess of 5 microm and 4 mm/s could be imparted at the fundamental frequency of 145 Hz. Using the same ultrasound transducer, excitation across the entire range of audio frequencies was obtained. Since the beam was focused on the reed, ultrasound stimulated excitation eliminated background effects observed during mechanical shaker excitation, such as vibrations of clamps and supports. The results obtained using single, dual and confocal ultrasound transducers in AM and two-beam modes, along with results obtained using a mechanical shaker and audio excitation using a speaker are discussed.

No effect of prolonged pulsed high frequency ultrasound imaging of the basilar membrane on cochlear function or hair cell survival found in an initial study.

PubMed

Landry, Thomas G; Bance, Manohar L; Adamson, Robert B; Brown, Jeremy A

2018-06-01

Miniature high frequency ultrasound devices show promise as tools for clinical middle ear and basal cochlea imaging and vibrometry. However, before clinical use it is important to verify that the ultrasound exposure does not damage the cochlea. In this initial study, electrophysiological responses of the cochlea were measured for a range of stimulus frequencies in both ears of anesthetized chinchillas, before and after exposing the organ of Corti region of one ear to pulsed focused ultrasound for 30 min. Measurements were again taken after an 11 day survival period. Cochlear tissue was examined with a confocal microscope for signs of damage to the cochlear hair cells. No significant change in response thresholds due to exposure was found, and no signs of ultrasound-induced tissue damage were observed, although one animal (out of ten) did have a region of extensive tissue damage in the exposed cochlea. However, after further analysis this was concluded to be not likely a result of the ultrasound exposure. Copyright © 2017 Elsevier B.V. All rights reserved.

Feasibility of low frequency ultrasound for water removal from crude oil emulsions.

PubMed

Antes, Fabiane G; Diehl, Liange O; Pereira, Juliana S F; Guimarães, Regina C L; Guarnieri, Ricardo A; Ferreira, Bianca M S; Dressler, Valderi L; Flores, Erico M M

2015-07-01

The feasibility of indirect application of low frequency ultrasound for demulsification of crude oil was investigated without using chemical demulsifiers. Experiments were performed in an ultrasonic bath with frequency of 35 kHz. Synthetic emulsions with water content of 12%, 35% and 50% and median of droplet size distribution (DSD), median D(0.5), of 5, 10 and 25 μm were prepared from crude oil with API density of 19 (heavy crude oil) and submitted to the proposed ultrasound-assisted demulsification procedure. Experimental conditions as temperature, time of exposition to ultrasound and ultrasonic power were evaluated. Separation of water from crude oil emulsion was observed for all emulsions investigated. Demulsification efficiency up to 65% was obtained for emulsion with 50% of water content and DSD of 10 μm. Higher efficiency of demulsification was achieved using US temperature of 45 °C and ultrasound power of 160 W by 15 min. Results obtained in this study showed that ultrasound could be considered a promising technology for industrial crude oil treatment and respective water removal. Copyright © 2015 Elsevier B.V. All rights reserved.

Nonequilibrium atmospheric pressure plasma jet using a combination of 50 kHz/2 MHz dual-frequency power sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou, Yong-Jie; Yuan, Qiang-Hua; Li, Fei

2013-11-15

An atmospheric pressure plasma jet is generated by dual sinusoidal wave (50 kHz and 2 MHz). The dual-frequency plasma jet exhibits the advantages of both low frequency and radio frequency plasmas, namely, the long plasma plume and the high electron density. The radio frequency ignition voltage can be reduced significantly by using dual-frequency excitation compared to the conventional radio frequency without the aid of the low frequency excitation source. A larger operating range of α mode discharge can be obtained using dual-frequency excitation which is important to obtain homogeneous and low-temperature plasma. A larger controllable range of the gas temperaturemore » of atmospheric pressure plasma could also be obtained using dual-frequency excitation.« less

Cross sectional survey of ultrasound use for central venous catheter insertion among resident physicians.

PubMed

Nomura, Jason T; Sierzenski, Paul R; Nace, Jason E; Bollinger, Melissa

2008-07-01

Use of ultrasound guidance for Central Venous Catheter insertion has been associated with decreased complications and increased success rates. Previous reports show low rates of use among physicians. Evaluation of the frequency of Ultrasound Guidance use for Central Venous Catheter insertion among residents at a teaching institution. A cross sectional electronic survey of resident physicians at a tertiary care teaching hospital was conducted to evaluate use of Ultrasound Guidance for Central Venous Catheterization. Assessment included self reported frequency of ultrasound guidance use, and volume of central venous catheter placement. Attitudes toward the use of ultrasound were assessed using Likert scales. There is a high rate. over 90%, of ultrasound guidance use for Internal Jugular central venous catheters among residents. The majority of residents use sterile real-time imaging with a single operator with a reported success rate greater then 80%. Resident use of ultrasound guidance for Internal Jugular central venous catheter insertion can be much higher than previously reported in the literature.

The utility of ultrasound in patients with melanoma.

PubMed

Uren, Roger F; Sanki, Amira; Thompson, John F

2007-11-01

The highest quality gray-scale ultrasound images are obtained with high-frequency transducers; however, such high frequencies do not penetrate more than a few centimeters into body tissue. Fortunately, in patients with melanoma, the structures of interest are close to the skin surface, making them ideal targets for examination with high-resolution ultrasound. These include primary cutaneous melanomas, uveal melanomas and the regional lymph nodes draining the skin that lie in the axilla, groin, neck and other locations. Although ultrasound study of primary melanomas arising in the skin and eye has provided some insights, a major role for ultrasound has evolved recently, to provide early detection of metastatic melanoma in regional lymph nodes. Ultrasound is clearly superior to clinical palpation of the nodes during follow-up and, when combined with guided fine-needle biopsy, allows the earliest possible surgical intervention for regional nodal metastases. In the future the use of ultrasound contrast agents may improve the sensitivity of ultrasound in the detection of very small metastatic deposits.

Effect of pulsed discharge on the ignition of pulse modulated radio frequency glow discharge at atmospheric pressure

NASA Astrophysics Data System (ADS)

Qiu, Shenjie; Guo, Ying; Han, Qianhan; Bao, Yun; Zhang, Jing; Shi, J. J.

2018-01-01

A pulsed discharge is introduced between two sequential pulse-modulated radio frequency glow discharges in atmospheric helium. The dependence of radio frequency discharge ignition on pulsed discharge intensity is investigated experimentally with the pulse voltage amplitudes of 650, 850, and 1250 V. The discharge characteristics and dynamics are studied in terms of voltage and current waveforms, and spatial-temporal evolution of optical emission. With the elevated pulsed discharge intensity of two orders of magnitude, the ignition of radio frequency discharge is enhanced by reducing the ignition time and achieving the stable operation with a double-hump spatial profile. The ignition time of radio frequency discharge is estimated to be 2.0 μs, 1.5 μs, and 1.0 μs with the pulse voltage amplitudes of 650, 850, and 1250 V, respectively, which is also demonstrated by the spatial-temporal evolution of optical emission at 706 and 777 nm.

Ultrasonic RF time series for early assessment of the tumor response to chemotherapy.

PubMed

Lin, Qingguang; Wang, Jianwei; Li, Qing; Lin, Chunyi; Guo, Zhixing; Zheng, Wei; Yan, Cuiju; Li, Anhua; Zhou, Jianhua

2018-01-05

Ultrasound radio-frequency (RF) time series have been shown to carry tissue typing information. To evaluate the potential of RF time series for early prediction of tumor response to chemotherapy, 50MCF-7 breast cancer-bearing nude mice were randomized to receive cisplatin and paclitaxel (treatment group; n = 26) or sterile saline (control group; n = 24). Sequential ultrasound imaging was performed on days 0, 3, 6, and 8 of treatment to simultaneously collect B-mode images and RF data. Six RF time series features, slope, intercept, S1, S2, S3 , and S4 , were extracted during RF data analysis and contrasted with microstructural tumor changes on histopathology. Chemotherapy administration reduced tumor growth relative to control on days 6 and 8. Compared with day 0, intercept, S1 , and S2 were increased while slope was decreased on days 3, 6, and 8 in the treatment group. Compared with the control group, intercept, S1, S2, S3 , and S4 were increased, and slope was decreased, on days 3, 6, and 8 in the treatment group. Tumor cell density decreased significantly in the latter on day 3. We conclude that ultrasonic RF time series analysis provides a simple way to noninvasively assess the early tumor response to chemotherapy.

Optimisation of ultrasound-assisted osmotic dehydration of sweet potato (Ipomea batatas) using response surface methodology.

PubMed

Oladejo, Ayobami Olayemi; Ma, Haile

2016-08-01

Sweet potato is a highly nutritious tuber crop that is rich in β-carotene. Osmotic dehydration is a pretreatment method for drying of fruit and vegetables. Recently, ultrasound technology has been applied in food processing because of its numerous advantages which include time saving, little damage to the quality of the food. Thus, there is need to investigate and optimise the process parameters [frequency (20-50 kHz), time (10-30 min) and sucrose concentration (20-60% w/v)] for ultrasound-assisted osmotic dehydration of sweet potato using response surface methodology. The optimised values obtained were frequency of 33.93 kHz, time of 30 min and sucrose concentration of 35.69% (w/v) to give predicted values of 21.62, 4.40 and 17.23% for water loss, solid gain and weight reduction, respectively. The water loss and weight reduction increased when the ultrasound frequency increased from 20 to 35 kHz and then decreased as the frequency increased from 35 to 50 kHz. The results from this work show that low ultrasound frequency favours the osmotic dehydration of sweet potato and also reduces the use of raw material (sucrose) needed for the osmotic dehydration of sweet potato. © 2015 Society of Chemical Industry. © 2015 Society of Chemical Industry.

Feasibility of Rotational Scan Ultrasound Imaging by an Angled High Frequency Transducer for the Posterior Segment of the Eye

PubMed Central

Paeng, Dong-Guk; Chang, Jin Ho; Chen, Ruimin; Humayun, Mark S.; Shung, K. Kirk

2009-01-01

High frequency ultrasound over 40 MHz has been used to image the anterior segment of the eye, but it is not suitable for the posterior segment due to the frequency-dependent attenuation of ultrasound and thus the limitation of penetration depth. This paper proposes a novel scan method to image the posterior segment of the eye with an angled high frequency (beyond 40 MHz) ultrasound needle transducer. In this method, the needle transducer is inserted into the eye through a small incision hole (∼1 mm in diameter) and rotated around the axial direction to form a cone-shaped imaging plane, allowing the spatial information of retinal vessels and diagnosis of their occlusion to be displayed. The feasibility of this novel technique was tested with images of a wire phantom, a polyimide tube, and an excised pig eye obtained by manually rotating a 40-MHz PMN-PT needle transducer with a beveled tip of 45°. From the results, we believe that rotational scan imaging will help expand the minimally invasive applications of high frequency ultrasound to other areas due to the capability of increased closeness of an angled needle transducer to structures of interest buried in other tissues. PMID:19411226

Feasibility of rotational scan ultrasound imaging by an angled high frequency transducer for the posterior segment of the eye.

PubMed

Paeng, Dong-Guk; Chang, Jin Ho; Chen, Ruimin; Humayun, Mark S; Shung, K Kirk

2009-03-01

High frequency ultrasound over 40 MHz has been used to image the anterior segment of the eye, but it is not suitable for the posterior segment due to the frequency dependent attenuation of ultrasound and thus the limitation of penetration depth. This paper proposes a novel scan method to image the posterior segment of the eye with an angled high frequency (beyond 40 MHz) ultrasound needle transducer. In this method, the needle transducer is inserted into the eye through a small incision hole (approximately 1 mm in diameter) and rotated around the axial direction to form a cone-shaped imaging plane, allowing the spatial information of retinal vessels and diagnosis of their occlusion to be displayed. The feasibility of this novel technique was tested with images of a wire phantom, a polyimide tube, and an excised pig eye obtained by manually rotating a 40-MHz PMN-PT needle transducer with a beveled tip of 45 degrees . From the results, we believe that rotational scan imaging will help expand the minimally invasive applications of high frequency ultrasound to other areas due to the capability of increased closeness of an angled needle transducer to structures of interest buried in other tissues.

Propogation loss with frequency of ultrasound guided waves in a composite metal-honeycomb structure

NASA Astrophysics Data System (ADS)

Saxena, Indu F.; Baid, Harsh K.; Guzman, Narciso; Kempen, Lothar U.; Mal, Ajit

2009-05-01

Non-destructive testing of critical structural components is time consuming, while necessary for maintaining safe operation. Large aerospace structures, such as the vertical stabilizers of aircraft undergo inspection at regular intervals for damage diagnostics. However, conventional techniques for damage detection and identification before repair can be scheduled are conducted off-line and therefore can take weeks. The use of guided ultrasound waves is being investigated to expedite damage detection in composites. We measure the frequency dependent loss of ultrasonic guided waves for a structure comprising a boron-nitride composite skin sandwiching an aluminum honeycomb. A wide range of ultrasound frequencies propagate as measured using PZTs, with the lowest attenuation observed about 200-250 kHz. These measurements are confirmed using optical fiber Bragg grating arrays used as ultrasound transducers.

Architecture Analysis of Wireless Power Transmission for Lunar Outposts

DTIC Science & Technology

2015-09-01

through his work on wireless communication using radio wave propagation for both transmitting and receiving high frequency electricity using a focusing...Administration nm nanometers NRC National Research Council PGT platform generic technologies PMAD power management and distribution RF radio frequency xiv...GHz (Marzwell 2008). While the slot antenna can handle frequencies between 70 GHz and 150 GHz, it has been optimized for 94 GHz and has a radio

Extremely Bendable, High-Performance Integrated Circuits Using Semiconducting Carbon Nanotube Networks for Digital, Analog, and Radio-Frequency Applications

DTIC Science & Technology

2012-02-07

circuits on mechanically flexible substrates for digital, analog and radio frequency applications. The asobtained thin-film transistors ( TFTs ) exhibit... flexible substrates for digital, analog and radio frequency applications. The as- obtained thin-film transistors ( TFTs ) exhibit highly uniform device...LCD) and organic light- emitting diode ( OLED ) displays lack the transparency and flexibility and are thus unsuitable for flexible electronic

Variability of fractal dimension of solar radio flux

NASA Astrophysics Data System (ADS)

Bhatt, Hitaishi; Sharma, Som Kumar; Trivedi, Rupal; Vats, Hari Om

2018-04-01

In the present communication, the variation of the fractal dimension of solar radio flux is reported. Solar radio flux observations on a day to day basis at 410, 1415, 2695, 4995, and 8800 MHz are used in this study. The data were recorded at Learmonth Solar Observatory, Australia from 1988 to 2009 covering an epoch of two solar activity cycles (22 yr). The fractal dimension is calculated for the listed frequencies for this period. The fractal dimension, being a measure of randomness, represents variability of solar radio flux at shorter time-scales. The contour plot of fractal dimension on a grid of years versus radio frequency suggests high correlation with solar activity. Fractal dimension increases with increasing frequency suggests randomness increases towards the inner corona. This study also shows that the low frequency is more affected by solar activity (at low frequency fractal dimension difference between solar maximum and solar minimum is 0.42) whereas, the higher frequency is less affected by solar activity (here fractal dimension difference between solar maximum and solar minimum is 0.07). A good positive correlation is found between fractal dimension averaged over all frequencies and yearly averaged sunspot number (Pearson's coefficient is 0.87).

47 CFR 2.1204 - Import conditions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... generations of a particular model under development are considered to be separate devices. (4) The radio... particular model under development are considered to be separate devices. (5) The radio frequency device is... offered for sale or marketed. (9) The radio frequency device is a medical implant transmitter inserted in...

47 CFR 2.1204 - Import conditions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... generations of a particular model under development are considered to be separate devices. (4) The radio... particular model under development are considered to be separate devices. (5) The radio frequency device is... offered for sale or marketed. (9) The radio frequency device is a medical implant transmitter inserted in...

47 CFR 76.616 - Operation near certain aeronautical and marine emergency radio frequencies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 4 2011-10-01 2011-10-01 false Operation near certain aeronautical and marine emergency radio frequencies. 76.616 Section 76.616 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Technical Standards § 76...

Ultrasound assisted nucleation and growth characteristics of glycine polymorphs--a combined experimental and analytical approach.

PubMed

Renuka Devi, K; Raja, A; Srinivasan, K

2015-05-01

For the first time, the effect of ultrasound in the diagnostic frequency range of 1-10 MHz on the nucleation and growth characteristics of glycine has been explored. The investigation employing the ultrasonic interferometer was carried out at a constant insonation time over a wide range of relative supersaturation from σ=-0.09 to 0.76 in the solution. Ultrasound promotes only α nucleation and completely inhibits both the β and γ nucleation in the system. The propagation of ultrasound assisted mass transport facilitates nucleation even at very low supersaturation levels in the solution. The presence of ultrasound exhibits a profound effect on nucleation and growth characteristics in terms of decrease in induction period, increase in nucleation rate and decrease in crystal size than its absence in the solution. With an increase in the frequency of ultrasound, a further decrease in induction period, increase in nucleation rate and decrease in the size of the crystal is noticed even at the same relative supersaturation levels. The increase in the nucleation rate explains the combined dominating effects of both the ultrasound frequency and the supersaturation in the solution. Analytically, the nucleation parameters of the nucleated polymorph have been deduced at different ultrasonic frequencies based on the classical nucleation theory and correlations with the experimental results have been obtained. Structural affirmation of the nucleated polymorph has been ascertained by powder X-ray diffraction. Copyright © 2014 Elsevier B.V. All rights reserved.

Unprecedentedly Strong and Narrow Electromagnetic Emissions Stimulated by High-Frequency Radio Waves in the Ionosphere

DOE Office of Scientific and Technical Information (OSTI.GOV)

Norin, L.; Leyser, T. B.; Nordblad, E.

2009-02-13

Experimental results of secondary electromagnetic radiation, stimulated by high-frequency radio waves irradiating the ionosphere, are reported. We have observed emission peaks, shifted in frequency up to a few tens of Hertz from radio waves transmitted at several megahertz. These emission peaks are by far the strongest spectral features of secondary radiation that have been reported. The emissions are attributed to stimulated Brillouin scattering, long predicted but hitherto never unambiguously identified in high-frequency ionospheric interaction experiments. The experiments were performed at the High-Frequency Active Auroral Research Program (HAARP), Alaska, USA.

Unprecedentedly strong and narrow electromagnetic emissions stimulated by high-frequency radio waves in the ionosphere.

PubMed

Norin, L; Leyser, T B; Nordblad, E; Thidé, B; McCarrick, M

2009-02-13

Experimental results of secondary electromagnetic radiation, stimulated by high-frequency radio waves irradiating the ionosphere, are reported. We have observed emission peaks, shifted in frequency up to a few tens of Hertz from radio waves transmitted at several megahertz. These emission peaks are by far the strongest spectral features of secondary radiation that have been reported. The emissions are attributed to stimulated Brillouin scattering, long predicted but hitherto never unambiguously identified in high-frequency ionospheric interaction experiments. The experiments were performed at the High-Frequency Active Auroral Research Program (HAARP), Alaska, USA.

The Radio Frequency Environment at 240-270 MHz with Application to Signal-of-Opportunity Remote Sensing

NASA Technical Reports Server (NTRS)

Piepmeier, Jeffrey R.; Vega, Manuel; Fritts, Matthew; Du Toit, Cornelis; Knuble, Joseph; Lin, Yao-Cheng; Nold, Benjamin; Garrison, James

2017-01-01

Low frequency observations are desired for soil moisture and biomass remote sensing. Long wavelengths are needed to penetrate vegetation and Earths land surface. In addition to the technical challenges of developing Earth observing spaceflight instruments operating at low frequencies, the radio frequency spectrum allocated to remote sensing is limited. Signal-of-opportunity remote sensing offers the chance to use existing signals exploiting their allocated spectrum to make Earth science measurements. We have made observations of the radio frequency environment around 240-270 MHz and discuss properties of desired and undesired signals.

High-frequency predictions for number counts and spectral properties of extragalactic radio sources. New evidence of a break at mm wavelengths in spectra of bright blazar sources

NASA Astrophysics Data System (ADS)

Tucci, M.; Toffolatti, L.; de Zotti, G.; Martínez-González, E.

2011-09-01

We present models to predict high-frequency counts of extragalactic radio sources using physically grounded recipes to describe the complex spectral behaviour of blazars that dominate the mm-wave counts at bright flux densities. We show that simple power-law spectra are ruled out by high-frequency (ν ≥ 100 GHz) data. These data also strongly constrain models featuring the spectral breaks predicted by classical physical models for the synchrotron emission produced in jets of blazars. A model dealing with blazars as a single population is, at best, only marginally consistent with data coming from current surveys at high radio frequencies. Our most successful model assumes different distributions of break frequencies, νM, for BL Lacs and flat-spectrum radio quasars (FSRQs). The former objects have substantially higher values of νM, implying that the synchrotron emission comes from more compact regions; therefore, a substantial increase of the BL Lac fraction at high radio frequencies and at bright flux densities is predicted. Remarkably, our best model is able to give a very good fit to all the observed data on number counts and on distributions of spectral indices of extragalactic radio sources at frequencies above 5 and up to 220 GHz. Predictions for the forthcoming sub-mm blazar counts from Planck, at the highest HFI frequencies, and from Herschel surveys are also presented. Appendices are available in electronic form at http://www.aanda.org

Assessment of carotid stiffness and intima-media thickness from ultrasound data: comparison between two methods.

PubMed

Bianchini, Elisabetta; Bozec, Erwan; Gemignani, Vincenzo; Faita, Francesco; Giannarelli, Chiara; Ghiadoni, Lorenzo; Demi, Marcello; Boutouyrie, Pierre; Laurent, Stéphane

2010-08-01

Increased arterial stiffness and carotid intima-media thickness (IMT) are considered independent predictors of cardiovascular events. The aim of this study was to compare a system recently developed in our laboratory for automatic assessment of these parameters from ultrasound image sequences to a reference radio frequency (RF) echo-tracking system. Common carotid artery scans of 21 patients with cardiovascular risk factors and 12 healthy volunteers were analyzed by both devices for the assessment of diameter (D), IMT, and distension (DeltaD). In the healthy volunteers, analyses were repeated twice to evaluate intraobserver variability. Agreement was evaluated by Bland-Altman analysis, whereas reproducibility was expressed as a coefficient of variation (CV). Regarding the agreement between the two systems, bias values +/- SD were 0.060 +/- 0.110 mm for D, -0.006 +/- 0.039 mm for IMT, and -0.016 +/- 0.039 mm for DeltaD. Intraobserver CVs were 2% +/- 2% for D, 5% +/- 5% for IMT, and 6% +/- 6% for DeltaD with the RF echo-tracking system and 2% +/- 1% for D, 6% +/- 6% for IMT, and 8% +/- 6% for DeltaD with our automated system. Although B-mode-based devices are less precise than RF-based ones, our automated system has good agreement with the reference method and comparable reproducibility, at least when high-quality images are analyzed. Hence, this study suggests that the presented system based on image processing from standard ultrasound scans is a suitable device for measuring IMT and local arterial stiffness parameters in clinical studies.

Abdominal ultrasound (image)

MedlinePlus

Abdominal ultrasound is a scanning technique used to image the interior of the abdomen. Like the X-ray, MRI, ... it has its place as a diagnostic tool. Ultrasound scans use high frequency sound waves to produce ...

Nonthermal effects of therapeutic ultrasound: the frequency resonance hypothesis.

PubMed

Johns, Lennart D

2002-07-01

To present the frequency resonance hypothesis, a possible mechanical mechanism by which treatment with non-thermal levels of ultrasound stimulates therapeutic effects. The review encompasses a 4-decade history but focuses on recent reports describing the effects of nonthermal therapeutic levels of ultrasound at the cellular and molecular levels. A search of MEDLINE from 1965 through 2000 using the terms ultrasound and therapeutic ultrasound. The literature provides a number of examples in which exposure of cells to therapeutic ultrasound under nonthermal conditions modified cellular functions. Nonthermal levels of ultrasound are reported to modulate membrane properties, alter cellular proliferation, and produce increases in proteins associated with inflammation and injury repair. Combined, these data suggest that nonthermal effects of therapeutic ultrasound can modify the inflammatory response. The concept of the absorption of ultrasonic energy by enzymatic proteins leading to changes in the enzymes activity is not novel. However, recent reports demonstrating that ultrasound affects enzyme activity and possibly gene regulation provide sufficient data to present a probable molecular mechanism of ultrasound's nonthermal therapeutic action. The frequency resonance hypothesis describes 2 possible biological mechanisms that may alter protein function as a result of the absorption of ultrasonic energy. First, absorption of mechanical energy by a protein may produce a transient conformational shift (modifying the 3-dimensional structure) and alter the protein's functional activity. Second, the resonance or shearing properties of the wave (or both) may dissociate a multimolecular complex, thereby disrupting the complex's function. This review focuses on recent studies that have reported cellular and molecular effects of therapeutic ultrasound and presents a mechanical mechanism that may lead to a better understanding of how the nonthermal effects of ultrasound may be therapeutic. Moreover, a better understanding of ultrasound's mechanical mechanism could lead to a better understanding of how and when ultrasound should be employed as a therapeutic modality.

Likelihood of Incomplete Kidney Tumor Ablation with Radio Frequency Energy: Degree of Enhancement Matters.

PubMed

Lay, Aaron H; Stewart, Jeremy; Canvasser, Noah E; Cadeddu, Jeffrey A; Gahan, Jeffrey C

2016-07-01

Larger size and clear cell histopathology are associated with worse outcomes for malignant renal tumors treated with radio frequency ablation. We hypothesize that greater tumor enhancement may be a risk factor for radio frequency ablation failure due to increased vascularity. A retrospective review of patients who underwent radio frequency ablation for renal tumors with contrast enhanced imaging available was performed. The change in Hounsfield units (HU) of the tumor from the noncontrast phase to the contrast enhanced arterial phase was calculated. Radio frequency ablation failure rates for biopsy confirmed malignant tumors were compared using the chi-squared test. Multivariate logistic analysis was performed to assess predictive variables for radio frequency ablation failure. Disease-free survival was calculated using Kaplan-Meier analysis. A total of 99 patients with biopsy confirmed malignant renal tumors and contrast enhanced imaging were identified. The incomplete ablation rate was significantly lower for tumors with enhancement less than 60 vs 60 HU or greater (0.0% vs 14.6%, p=0.005). On multivariate logistic regression analysis tumor enhancement 60 HU or greater (OR 1.14, p=0.008) remained a significant predictor of incomplete initial ablation. The 5-year disease-free survival for size less than 3 cm was 100% vs 69.2% for size 3 cm or greater (p <0.01), while 5-year disease-free survival for HU change less than 60 was 100% vs 92.4% for HU change 60 or greater (p=0.24). Biopsy confirmed malignant renal tumors, which exhibit a change in enhancement of 60 HU or greater, experience a higher rate of incomplete initial tumor ablation than tumors with enhancement less than 60 HU. Size 3 cm or greater portends worse 5-year disease-free survival after radio frequency ablation. The degree of enhancement should be considered when counseling patients before radio frequency ablation. Copyright © 2016 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Optimal beamforming in ultrasound using the ideal observer.

PubMed

Abbey, Craig K; Nguyen, Nghia Q; Insana, Michael F

2010-08-01

Beamforming of received pulse-echo data generally involves the compression of signals from multiple channels within an aperture. This compression is irreversible, and therefore allows the possibility that information relevant for performing a diagnostic task is irretrievably lost. The purpose of this study was to evaluate information transfer in beamforming using a previously developed ideal observer model to quantify diagnostic information relevant to performing a task. We describe an elaborated statistical model of image formation for fixed-focus transmission and single-channel reception within a moving aperture, and we use this model on a panel of tasks related to breast sonography to evaluate receive-beamforming approaches that optimize the transfer of information. Under the assumption that acquisition noise is well described as an additive wide-band Gaussian white-noise process, we show that signal compression across receive-aperture channels after a 2-D matched-filtering operation results in no loss of diagnostic information. Across tasks, the matched-filter beamformer results in more information than standard delay-and-sum beamforming in the subsequent radio-frequency signal by a factor of two. We also show that for this matched filter, 68% of the information gain can be attributed to the phase of the matched-filter and 21% can be attributed to the amplitude. A 1-D matched filtering along axial lines shows no advantage over delay-andsum, suggesting an important role for incorporating correlations across different aperture windows in beamforming. We also show that a post-compression processing before the computation of an envelope is necessary to pass the diagnostic information in the beamformed radio-frequency signal to the final envelope image.

Modifying a Commercial Centrifuge to Reduce Electromagnetic Interference and Evaluating Functionality of Ultrasound Equipment

NASA Technical Reports Server (NTRS)

Greening, Gage J.

2016-01-01

The Project Management and Engineering Branch (SF4) supports the Human Health and Performance Directorate (HH&P) and is responsible for developing and supporting human systems hardware for the International Space Station (ISS). When a principal investigator's (PI) medical research project on the ISS is accepted, SF4 develops the necessary hardware and software to transport to the ISS. The two projects I primarily worked on were the centrifuge and ultrasound projects. Centrifuge: One concern with spacecraft such as the ISS is electromagnetic interference (EMI) from onboard equipment, typically from radio waves (frequencies of 3 kHz to 300 GHz), which can negatively affect nearby circuitry. Standard commercial centrifuges produce EMI above safety limits, so my task was to help reduce EMI production from this equipment. Two centrifuges were tested: one unmodified as a control and one modified. To reduce EMI below safety limits, one centrifuge was modified to become a Faraday shield, in which significant electrical contact was made between all regions of the centrifuge housing. This included removing non-conductive paint, applying conductive fabric to the lid and foam sealer, adding a 10,000 µF decoupling capacitor across the power supply, and adding copper adhesive-mount gaskets to the housing interior. EMI testing of both centrifuges was performed in the EMI/EMC Control Test and Measurement Facility. EMI for both centrifuges was below safety limits for frequencies between 10 MHz and 15 GHz (pass); however, between 14 kHz and 10 MHz, EMI for the unmodified centrifuge exceeded safety limits (fail) as expected. Alternatively, for the modified centrifuge with the Faraday shield, EMI was below the safely limit of 55 dBµV/m for electromagnetic frequencies between 14 kHz and 10 MHz. This result indicates our modifications were successful. The successful EMI test allowed us to communicate with the vendor what modifications they needed to make to their commercial unit to meet our specifications and to understand what needs to be done in lab to the new centrifuge. Our modifications will provide a standard for readying centrifuges for future missions. Once the new modified centrifuge arrives by the vendor, it will need to undergo EMI testing again for validation. The centrifuge is also in the process of compatibility testing with a custom stowage drawer, which is an ongoing project in SF4. Both of these items will be payloads on future missions to the ISS for various research purposes. Ultrasound: ISS currently has an onboard ultrasound (Ultrasound 2 system) for research and medical purposes. Every piece of medical flight hardware has an equivalent ground-unit so instrumentation can be routinely evaluated and transported to the ISS if necessary. The ground-unit ultrasound equipment must be evaluated every six months using a task performance sheet (TPS). A TPS is a document, written by the appropriate scientists and engineers, which describes how to run equipment and is written in such a way that astronauts with unspecialized training can follow the tasks. I was responsible for performing six TPSs on a combination of three ultrasounds and two video power converters (VPCs). Performing a TPS involves checking out and computationally documenting each piece of equipment removed from storage locations, setting up hardware and software, performing tasks to verify functionality, returning equipment, and logging items back into the computerized system. My work revealed all ground-unit ultrasounds were functioning properly. Because of proper function, a discrepancy report (DR) did not have to be opened. The TPS was then passed along to the Quality Engineering (QE) for review and ultimately given to Quality Assurance (QA). Other projects: In addition to my main projects, I participated in other tasks including troubleshooting an EEG headband, volunteering for an ultrasound training research study, and conformal coating printed circuit boards. My internship at SF4 has helped me understand how space systems hardware development for the ISS fits into NASA's mission and vision.

Solar radio continuum storms

NASA Technical Reports Server (NTRS)

1974-01-01

Radio noise continuum emission observed in metric and decametric wave frequencies is discussed. The radio noise is associated with actively varying sunspot groups accompanied by the S-component of microwave radio emissions. It is shown that the S-component emission in microwave frequencies generally occurs several days before the emission of the noise continuum storms of lower frequencies. It is likely that energetic electrons, 10 to 100 Kev, accelerated in association with the variation of sunspot magnetic fields, are the sources of the radio emissions. A model is considered to explain the relation of burst storms on radio noise. An analysis of the role of energetic electrons on the emissions of both noise continuum and type III burst storms is presented. It is shown that instabilities associated with the electrons and their relation to their own stabilizing effects are important in interpreting both of these storms.

Signal Identification and Isolation Utilizing Radio Frequency Photonics

DTIC Science & Technology

2017-09-01

analyzers can measure the frequency of signals and filters can be used to separate the signals apart from one another. This report will review...different techniques for spectrum analysis and isolation. 15. SUBJECT TERMS radio frequency, photonics, spectrum analyzer, filters 16. SECURITY CLASSIFICATION...Analyzers .......................................................................................... 3 3.2 Frequency Identification using Filters

78 FR 58487 - Airworthiness Directives; The Boeing Company Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-24

... display units (DUs). These DUs exhibited susceptibility to radio frequency emissions in WiFi frequency... certification of WiFi system installations. The phase 3 DUs provide primary flight information including... flickering and blanking when subjected to radio frequency emissions in WiFi frequency bands at radiated power...

Dynamic adsorption properties of n-alkyl glucopyranosides determine their ability to inhibit cytolysis mediated by acoustic cavitation.

PubMed

Sostaric, Joe Z; Miyoshi, Norio; Cheng, Jason Y; Riesz, Peter

2008-10-09

Suspensions of human leukemia (HL-60) cells readily undergo cytolysis when exposed to ultrasound above the acoustic cavitation threshold. However, n-alkyl glucopyranosides (hexyl, heptyl, and octyl) completely inhibit ultrasound-induced (1057 kHz) cytolysis (Sostaric, et al. Free Radical Biol. Med. 2005, 39, 1539-1548). The efficacy of protection from ultrasound-induced cytolysis was determined by the n-alkyl chain length of the glucopyranosides, indicating that protection efficacy depended on adsorption of n-alkyl glucopyranosides to the gas/solution interface of cavitation bubbles and/or the lipid membrane of cells. The current study tests the hypothesis that "sonoprotection" (i.e., protection of cells from ultrasound-induced cytolysis) in vitro depends on the adsorption of glucopyranosides at the gas/solution interface of cavitation bubbles. To test this hypothesis, the effect of ultrasound frequency (from 42 kHz to 1 MHz) on the ability of a homologous series of n-alkyl glucopyranosides to protect cells from ultrasound-induced cytolysis was investigated. It is expected that ultrasound frequency will affect sonoprotection ability since the nature of the cavitation bubble field will change. This will affect the relative importance of the possible mechanisms for ultrasound-induced cytolysis. Additionally, ultrasound frequency will affect the lifetime and rate of change of the surface area of cavitation bubbles, hence the dynamically controlled adsorption of glucopyranosides to their surface. The data support the hypothesis that sonoprotection efficiency depends on the ability of glucopyranosides to adsorb at the gas/solution interface of cavitation bubbles.

3D conformal MRI-guided transurethral ultrasound therapy: results of gel phantom experiments

NASA Astrophysics Data System (ADS)

N'Djin, W. A.; Burtnyk, M.; McCormick, S.; Bronskill, M.; Chopra, R.

2011-09-01

MRI-guided transurethral ultrasound therapy shows promise for minimally invasive treatment of localized prostate cancer. Previous in-vivo studies demonstrated the feasibility of performing conservative treatments using real-time temperature feedback to control accurately the establishment of coagulative lesions within circumscribed prostate regions. This in-vitro study tested device configuration and control options for achieving full prostate treatments. A multi-channel MRI compatible ultrasound therapy system was evaluated in gel phantoms using 3 canine prostate models. Prostate profiles were 5 mm-step-segmented from T2-weighted MR images performed during previous in-vivo experiments. During ultrasound exposures, each ultrasound element was controlled independently by the 3D controller. Decisions on acoustic power, frequency, and device rotation rate were made in real time based on MR thermometry feedback and prostate radii. Low and high power treatment approaches using maximum acoustic powers of 10 or 20 W.cm-2 were tested as well as single and dual-frequency strategies (4.05/13.10 MHz). The dual-frequency strategy used either the fundamental frequency or the 3rd harmonic component, depending on the prostate radius. The 20 W.cm-2 dual frequency approach was the most efficient configuration in achieving full prostate treatments. Treatment times were about half the duration of those performed with 10 W.cm-2 configurations. Full prostate coagulations were performed in 16.3±6.1 min at a rate of 1.8±0.2 cm3.min-1, and resulted in very little undertreated tissue (<3%). Surrounding organs positioned beyond a safety distance of 1.4±1.0 mm from prostate boundaries were not damaged, particularly rectal wall tissues. In this study, a 3D, MR-thermometry-guided transurethral ultrasound therapy was validated in vitro in a tissue-mimicking phantom for performing full prostate treatment. A dual-frequency configuration with 20 W.cm-2 ultrasound intensity exposure showed good results with direct application to full human prostate treatments.

47 CFR 90.275 - Selection and assignment of frequencies in the 421-430 MHz band.

Code of Federal Regulations, 2010 CFR

2010-10-01

... specify the frequencies in which the proposed system will operate pursuant to a recommendation by a...) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Standards for Special Frequencies or...

47 CFR 90.275 - Selection and assignment of frequencies in the 421-430 MHz band.

Code of Federal Regulations, 2011 CFR

2011-10-01

... specify the frequencies in which the proposed system will operate pursuant to a recommendation by a...) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Standards for Special Frequencies or...

Providing hydrogen maser timing stability to orbiting VLBI radio telescope observations by post-measurement compensation of linked frequency standard imperfections

NASA Astrophysics Data System (ADS)

Springett, James C.

1994-05-01

Orbiting VLBI (OVLBI) astronomical observations are based upon measurements acquired simultaneously from ground-based and earth-orbiting radio telescopes. By the mid-1990s, two orbiting VLBI observatories, Russia's Radioastron and Japan's VSOP, will augment the worldwide VLBI network, providing baselines to earth radio telescopes as large as 80,000 km. The challenge for OVLBI is to effectuate space to ground radio telescope data cross-correlation (the observation) to a level of integrity currently achieved between ground radio telescopes. VLBI radio telescopes require ultrastable frequency and timing references in order that long term observations may be made without serious cross-correlation loss due to frequency source drift and phase noise. For this reason, such instruments make use of hydrogen maser frequency standards. Unfortunately, space-qualified hydrogen maser oscillators are currently not available for use on OVLBI satellites. Thus, the necessary long-term stability needed by the orbiting radio telescope may only be obtained by microwave uplinking a ground-based hydrogen maser derived frequency to the satellite. Although the idea of uplinking the frequency standard intrinsically seems simple, there are many 'contaminations' which degrade both the long and short term stability of the transmitted reference. Factors which corrupt frequency and timing accuracy include additive radio and electronic circuit thermal noise, slow or systematic phase migration due to changes of electronic circuit temporal operating conditions (especially temperature), ionosphere and troposphere induced scintillations, residual Doppler-incited components, and microwave signal multipath propagation. What is important, though, is to realize that ultimate stability does not have to be achieved in real-time. Instead, information needed to produce a high degree of coherence in the subsequent cross-correlation operation may be derived from a two-way coherent radio link, recorded and later introduced as compensations adjunct to the VLBI correlation process. Accordingly, this paper examines the technique for stable frequency/time transfer within the OVLBI system, together with a critique of the types of link degradation components which must be compensated, and the figures of merit known as coherence factors.

Providing hydrogen maser timing stability to orbiting VLBI radio telescope observations by post-measurement compensation of linked frequency standard imperfections

NASA Technical Reports Server (NTRS)

Springett, James C.

1994-01-01

Orbiting VLBI (OVLBI) astronomical observations are based upon measurements acquired simultaneously from ground-based and earth-orbiting radio telescopes. By the mid-1990s, two orbiting VLBI observatories, Russia's Radioastron and Japan's VSOP, will augment the worldwide VLBI network, providing baselines to earth radio telescopes as large as 80,000 km. The challenge for OVLBI is to effectuate space to ground radio telescope data cross-correlation (the observation) to a level of integrity currently achieved between ground radio telescopes. VLBI radio telescopes require ultrastable frequency and timing references in order that long term observations may be made without serious cross-correlation loss due to frequency source drift and phase noise. For this reason, such instruments make use of hydrogen maser frequency standards. Unfortunately, space-qualified hydrogen maser oscillators are currently not available for use on OVLBI satellites. Thus, the necessary long-term stability needed by the orbiting radio telescope may only be obtained by microwave uplinking a ground-based hydrogen maser derived frequency to the satellite. Although the idea of uplinking the frequency standard intrinsically seems simple, there are many 'contaminations' which degrade both the long and short term stability of the transmitted reference. Factors which corrupt frequency and timing accuracy include additive radio and electronic circuit thermal noise, slow or systematic phase migration due to changes of electronic circuit temporal operating conditions (especially temperature), ionosphere and troposphere induced scintillations, residual Doppler-incited components, and microwave signal multipath propagation. What is important, though, is to realize that ultimate stability does not have to be achieved in real-time. Instead, information needed to produce a high degree of coherence in the subsequent cross-correlation operation may be derived from a two-way coherent radio link, recorded and later introduced as compensations adjunct to the VLBI correlation process. Accordingly, this paper examines the technique for stable frequency/time transfer within the OVLBI system, together with a critique of the types of link degradation components which must be compensated, and the figures of merit known as coherence factors.

Modes of elastic plates and shells in water driven by modulated radiation pressure of focused ultrasound

NASA Astrophysics Data System (ADS)

Marston, Philip L.; Daniel, Timothy D.; Abawi, Ahmad T.; Kirsteins, Ivars

2015-11-01

The modulated radiation pressure (MRP) of ultrasound has been used for decades to selectively excite low frequency modes associated with surface tension of fluid objects in water. Much less is known about the excitation of low frequency modes of less compliant metallic objects. Here we use MRP of focused ultrasound to excite resonant flexural vibrations of a circular metal plate in water. The source transducer was driven with a double-sideband suppressed carrier voltage as in. The response of the target (detected with a hydrophone) was at twice the modulation frequency and proportional to the square of the drive voltage. Since the radiation pressure of focused beams is spatially localized, mode shapes could be identified by scanning the source along the target while measuring the target's response. Additional measurements were done with an open-ended water-filled copper circular cylindrical shell in which resonant frequencies and mode shapes were also identified. These experiments show how focused ultrasound can be used to identify low-frequency modes of elastic objects without direct contact. Supported by ONR.

Phase-space topography characterization of nonlinear ultrasound waveforms.

PubMed

Dehghan-Niri, Ehsan; Al-Beer, Helem

2018-03-01

Fundamental understanding of ultrasound interaction with material discontinuities having closed interfaces has many engineering applications such as nondestructive evaluation of defects like kissing bonds and cracks in critical structural and mechanical components. In this paper, to analyze the acoustic field nonlinearities due to defects with closed interfaces, the use of a common technique in nonlinear physics, based on a phase-space topography construction of ultrasound waveform, is proposed. The central idea is to complement the "time" and "frequency" domain analyses with the "phase-space" domain analysis of nonlinear ultrasound waveforms. A nonlinear time series method known as pseudo phase-space topography construction is used to construct equivalent phase-space portrait of measured ultrasound waveforms. Several nonlinear models are considered to numerically simulate nonlinear ultrasound waveforms. The phase-space response of the simulated waveforms is shown to provide different topographic information, while the frequency domain shows similar spectral behavior. Thus, model classification can be substantially enhanced in the phase-space domain. Experimental results on high strength aluminum samples show that the phase-space transformation provides a unique detection and classification capabilities. The Poincaré map of the phase-space domain is also used to better understand the nonlinear behavior of ultrasound waveforms. It is shown that the analysis of ultrasound nonlinearities is more convenient and informative in the phase-space domain than in the frequency domain. Copyright © 2017 Elsevier B.V. All rights reserved.

Planck early results. XV. Spectral energy distributions and radio continuum spectra of northern extragalactic radio sources

DOE PAGES

Aatrokoski, J.

2011-12-01

Spectral energy distributions (SEDs) and radio continuum spectra are presented for a northern sample of 104 extragalactic radio sources, based on the Planck Early Release Compact Source Catalogue (ERCSC) and simultaneous multifrequency data. The nine Planck frequencies, from 30 to 857GHz, are complemented by a set of simultaneous observations ranging from radio to gamma-rays. This is the first extensive frequency coverage in the radio and millimetre domains for an essentially complete sample of extragalactic radio sources, and it shows how the individual shocks, each in their own phase of development, shape the radio spectra as they move in the relativisticmore » jet. The SEDs presented in this paper were fitted with second and third degree polynomials to estimate the frequencies of the synchrotron and inverse Compton (IC) peaks, and the spectral indices of low and high frequency radio data, including the Planck ERCSC data, were calculated. SED modelling methods are discussed, with an emphasis on proper, physical modelling of the synchrotron bump using multiple components. Planck ERCSC data also suggest that the original accelerated electron energy spectrum could be much harder than commonly thought, with power-law index around 1.5 instead of the canonical 2.5. The implications of this are discussed for the acceleration mechanisms effective in blazar shock. Furthermore in many cases the Planck data indicate that gamma-ray emission must originate in the same shocks that produce the radio emission.« less

A novel dual-frequency imaging method for intravascular ultrasound applications.

PubMed

Qiu, Weibao; Chen, Yan; Wong, Chi-Man; Liu, Baoqiang; Dai, Jiyan; Zheng, Hairong

2015-03-01

Intravascular ultrasound (IVUS), which is able to delineate internal structures of vessel wall with fine spatial resolution, has greatly enriched the knowledge of coronary atherosclerosis. A novel dual-frequency imaging method is proposed in this paper for intravascular imaging applications. A probe combined two ultrasonic transducer elements with different center frequencies (36 MHz and 78 MHz) is designed and fabricated with PMN-PT single crystal material. It has the ability to balance both imaging depth and resolution, which are important imaging parameters for clinical test. A dual-channel imaging platform is also proposed for real-time imaging, and this platform has been proven to support programmable processing algorithms, flexible imaging control, and raw RF data acquisition for IVUS applications. Testing results show that the -6 dB axial and lateral imaging resolutions of low-frequency ultrasound are 78 and 132 μm, respectively. In terms of high-frequency ultrasound, axial and lateral resolutions are determined to be as high as 34 and 106 μm. In vitro intravascular imaging on healthy swine aorta is conducted to demonstrate the performance of the dual-frequency imaging method for IVUS applications. Copyright © 2014 Elsevier B.V. All rights reserved.

Electrophysiological examination and high frequency ultrasonography for diagnosis of radial nerve torsion and compression

PubMed Central

Shi, Miao; Qi, Hengtao; Ding, Hongyu; Chen, Feng; Xin, Zhaoqin; Zhao, Qinghua; Guan, Shibing; Shi, Hao

2018-01-01

Abstract This study aims to evaluate the value of electrophysiological examination and high frequency ultrasonography in the differential diagnosis of radial nerve torsion and radial nerve compression. Patients with radial nerve torsion (n = 14) and radial nerve compression (n = 14) were enrolled. The results of neurophysiological and high frequency ultrasonography were compared. Electrophysiological examination and high-frequency ultrasonography had a high diagnostic rate for both diseases with consistent results. Of the 28 patients, 23 were positive for electrophysiological examination, showing decreased amplitude and decreased conduction velocity of radial nerve; however, electrophysiological examination cannot distinguish torsion from compression. A total of 27 cases showed positive in ultrasound examinations among all 28 cases. On ultrasound images, the nerve was thinned at torsion site whereas thickened at the distal ends of torsion. The diameter and cross-sectional area of torsion or compression determined the nerve damage, and ultrasound could locate the nerve injury site and measure the length of the nerve. Electrophysiological examination and high-frequency ultrasonography can diagnose radial neuropathy, with electrophysiological examination reflecting the neurological function, and high-frequency ultrasound differentiating nerve torsion from compression. PMID:29480857

Ultrasound effects on the assembly of casein micelles in reconstituted skim milk.

PubMed

Liu, Zheng; Juliano, Pablo; Williams, Roderick P W; Niere, Julie; Augustin, Mary Ann

2014-05-01

Reconstituted skim milks (10 % w/w total solids, pH 6·7-8·0) were ultrasonicated (20, 400 or 1600 kHz at a specific energy input of 286 kJ/kg) at a bulk milk temperature of <30 °C. Application of ultrasound to milk at different pH altered the assembly of the casein micelle in milk, with greater effects at higher pH and lower frequency. Low frequency ultrasound caused greater disruption of casein micelles causing release of protein from the micellar to the serum phase than high frequency. The released protein re-associated to form aggregates of smaller size but with surface charge similar to the casein micelles in the original milk. Ultrasound may be used as a physical intervention to alter the size of the micelles and the partitioning of caseins between the micellar and serum phases in milk. The altered protein equilibria induced by ultrasound treatment may have potential for the development of milk with novel functionality.

Observer efficiency in discrimination tasks simulating malignant and benign breast lesions imaged with ultrasound

PubMed Central

Abbey, Craig K.; Zemp, Roger J.; Liu, Jie; Lindfors, Karen K.; Insana, Michael F.

2009-01-01

We investigate and extend the ideal observer methodology developed by Smith and Wagner to detection and discrimination tasks related to breast sonography. We provide a numerical approach for evaluating the ideal observer acting on radio-frequency (RF) frame data, which involves inversion of large nonstationary covariance matrices, and we describe a power-series approach to computing this inverse. Considering a truncated power series suggests that the RF data be Wiener-filtered before forming the final envelope image. We have compared human performance for Wiener-filtered and conventional B-mode envelope images using psychophysical studies for 5 tasks related to breast cancer classification. We find significant improvements in visual detection and discrimination efficiency in four of these five tasks. We also use the Smith-Wagner approach to distinguish between human and processing inefficiencies, and find that generally the principle limitation comes from the information lost in computing the final envelope image. PMID:16468454

Radio interference in the near-earth environment

NASA Technical Reports Server (NTRS)

Erickson, W. C.

1988-01-01

Natural and man-made radio frequency interference (RFI) are potentially serious obstacles to the successful operation of an array of spacecraft used for low frequency (1 to 30 MHz) radio interferometry in the near-earth environment. Several satellites and planetary probes have carried radio astronomy experiments, and the moderate data base that they provide are examined to help understand the near-earth RFI environment. The general conclusion is that the region of space within 100 earth-radii of the earth is a hostile environment for any radio astronomy experiment. If a low frequency array in earth orbit is to yield useful astronomical results, severe interference problems must be anticipated and overcome. A number of recommendations are made to further examine the feasibility of such an array.

A 100-200 MHz ultrasound biomicroscope.

PubMed

Knspik, D A; Starkoski, B; Pavlin, C J; Foster, F S

2000-01-01

The development of higher frequency ultrasound imaging systems affords a unique opportunity to visualize living tissue at the microscopic level. This work was undertaken to assess the potential of ultrasound imaging in vivo using the 100-200 MHz range. Spherically focused lithium niobate transducers were fabricated. The properties of a 200 MHz center frequency device are described in detail. This transducer showed good sensitivity with an insertion loss of 18 dB at 200 MHz. Resolution of 14 /spl mu/m in the lateral direction and 12 /spl mu/m in the axial direction was achieved with f/1.14 focusing. A linear mechanical scan system and a scan converter were used to generate B-scan images at a frame rate up to 12 frames per second. System performance in B-mode imaging is limited by frequency dependent attenuation in tissues. An alternative technique, zone-focus image collection, was investigated to extend depth of field. Images of coronary arteries, the eye, and skin are presented along with some preliminary correlations with histology. These results demonstrate the feasibility of ultrasound biomicroscopy In the 100-200 MHz range. Further development of ultrasound backscatter imaging at frequencies up to and above 200 MHz will contribute valuable information about tissue microstructure.

Numerical simulations of particle acceleration and low frequency radio emission in stellar environments

NASA Astrophysics Data System (ADS)

Paraskevi Moschou, Sofia; Sokolov, Igor; Cohen, Ofer; Drake, Jeremy J.; Borovikov, Dmitry; Alvarado-Gomez, Julian D.; Garraffo, Cecilia

2018-06-01

Due to their favorable atmospheric window radio waves are a useful tool for ground-based observations of astrophysical systems throughout a plethora of scales, from cosmological down to planetary ones. A wide range of physical mechanisms, from thermal processes to eruptive events linked to magnetic reconnection, can generate emission in radio frequencies. Radio waves have the distinct characteristic that they follow curved paths as they propagate in stratified environments, such as the solar corona, due to their dependence on the refraction index. Low frequency radio rays in particular are affected the most by refraction.Solar radio observations are of particular importance, since it is possible to spatially resolve the Sun and its corona and gain insights on highly dynamic and complex radio-emitting phenomena. The multi-scale problem of particle acceleration and energy partition between CMEs, flares and SEPs requires both MHD and kinetic considerations to account for the emission and mass propagation through the interplanetary space.Radio observations can play a significant role in the rapidly developing area of exoplanetary research and provide insights on the stellar environments of those systems. Even though a large number of flares has been observed for different stellar types, nevertheless there is a lack of stellar CME observations. Currently, the most promising method to incontrovertibly observe stellar CMEs is through Type II radio bursts. Low frequency radio emission can also be produced by the interaction of a magnetized planet with the stellar wind of the host star.The above mentioned characteristics of radio-waves make their integration into numerical simulations imperative for capturing and disentangling the complex radio emitting processes along the actual radio paths and provide the observers with detection limits for future Earth- and space-based missions. Radio synthetic imaging tools incorporated in realistic computational codes are already available for solar radio-emitting processes with different physical and observational characteristics.

[Evidence of lacrimal plugs via high resolution ultrasound].

PubMed

Tost, Frank H W; Darman, Jacques

2003-07-01

The practical value of high-frequency ultrasound (transducer frequency of 20 MHz) for studying lacrimal plugs positioned into canaliculi was proved. Twelve patients with twenty intracanalicular plugs and two punctum plugs were examined via high-frequency B-scan ultrasonography using 20 MHz transducer (model I3 Sacramento, USA). Detection and localisation of the intracanalicular plugs was made by a 20 MHz sector scanner. The ultrasound examinations were performed 1 - 24 month after the placement of lacrimal plugs. After patient's head positioning, the high-frequency ultrasound investigation was done via immersion fluid (2 % methylcellulose). All patients with dry eye treated by lacrimal plug implant showed echographic structure in the lacrimal canaliculus. In transversal echograms it was possible to image both canaliculi together when the lids were half-closed. Contrary to the normal state, it was not necessary to inject viscous fluid into the canaliculus. High-resolution ultrasound was able to differentiate the normal canaliculus from the findings after plug placement. The echograms can vary from one plug type to another. Highly reflective structures were found after the placement of silicone intracanalicular plugs, e. g. HERRICK-Plug. In contrast, the ultrasonic image taken through acrylic polymer intracanalicular plugs showed homogeneous small reflective inner structure, e. g. SMART-Plug. However, smooth and flat acoustic interface between acrylic polymer plug and the lacrimal canaliculus produced strong echoes. 20 MHz ultrasound seems to be well suited for the detection and localisation of intracanalicular plugs. By use of 20 MHz ultrasound scans it is possible to get high-quality images of the intracanalicular plug and around lacrimal canaliculus. Compared with UBM, the depth of penetration is much higher with negligible resolution. On the whole, we believe that 20 MHz ultrasound can become a useful tool for evaluating the placement of intracanalicular plugs after insertion.

47 CFR 90.175 - Frequency coordinator requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... a frequency and/or transmitter site location. (18) Applications for base, mobile, or control... Section 90.175 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Policies Governing the Assignment of Frequencies § 90.175...

47 CFR 90.175 - Frequency coordinator requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... a frequency and/or transmitter site location. (18) Applications for base, mobile, or control... Section 90.175 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Policies Governing the Assignment of Frequencies § 90.175...

Characteristics of Radio-Frequency Circuits Utilizing Ferroelectric Capacitors

NASA Technical Reports Server (NTRS)

Eskridge, Michael; Gui, Xiao; MacLeod, Todd; Ho, Fat D.

2011-01-01

Ferroelectric capacitors, most commonly used in memory circuits and variable components, were studied in simple analog radio-frequency circuits such as the RLC resonator and Colpitts oscillator. The goal was to characterize the RF circuits in terms of frequency of oscillation, gain, etc, using ferroelectric capacitors. Frequencies of oscillation of both circuits were measured and studied a more accurate resonant frequency can be obtained using the ferroelectric capacitors. Many experiments were conducted and data collected. A model to simulate the experimental results will be developed. Discrepancies in gain and frequency in these RF circuits when conventional capacitors are replaced with ferroelectric ones were studied. These results will enable circuit designers to anticipate the effects of using ferroelectric components in their radio- frequency applications.

47 CFR 18.101 - Basis and purpose.

Code of Federal Regulations, 2012 CFR

2012-10-01

... industrial, scientific, and medical equipment (ISM) that emits electromagnetic energy on frequencies within the radio frequency spectrum in order to prevent harmful interference to authorized radio...

47 CFR 18.101 - Basis and purpose.

Code of Federal Regulations, 2013 CFR

2013-10-01

... industrial, scientific, and medical equipment (ISM) that emits electromagnetic energy on frequencies within the radio frequency spectrum in order to prevent harmful interference to authorized radio...

47 CFR 18.101 - Basis and purpose.

Code of Federal Regulations, 2010 CFR

2010-10-01

... industrial, scientific, and medical equipment (ISM) that emits electromagnetic energy on frequencies within the radio frequency spectrum in order to prevent harmful interference to authorized radio...

47 CFR 18.101 - Basis and purpose.

Code of Federal Regulations, 2011 CFR

2011-10-01

... industrial, scientific, and medical equipment (ISM) that emits electromagnetic energy on frequencies within the radio frequency spectrum in order to prevent harmful interference to authorized radio...

47 CFR 18.101 - Basis and purpose.

Code of Federal Regulations, 2014 CFR

2014-10-01

... industrial, scientific, and medical equipment (ISM) that emits electromagnetic energy on frequencies within the radio frequency spectrum in order to prevent harmful interference to authorized radio...

Developing High-Frequency Quantitative Ultrasound Techniques to Characterize Three-Dimensional Engineered Tissues

NASA Astrophysics Data System (ADS)

Mercado, Karla Patricia E.

Tissue engineering holds great promise for the repair or replacement of native tissues and organs. Further advancements in the fabrication of functional engineered tissues are partly dependent on developing new and improved technologies to monitor the properties of engineered tissues volumetrically, quantitatively, noninvasively, and nondestructively over time. Currently, engineered tissues are evaluated during fabrication using histology, biochemical assays, and direct mechanical tests. However, these techniques destroy tissue samples and, therefore, lack the capability for real-time, longitudinal monitoring. The research reported in this thesis developed nondestructive, noninvasive approaches to characterize the structural, biological, and mechanical properties of 3-D engineered tissues using high-frequency quantitative ultrasound and elastography technologies. A quantitative ultrasound technique, using a system-independent parameter known as the integrated backscatter coefficient (IBC), was employed to visualize and quantify structural properties of engineered tissues. Specifically, the IBC was demonstrated to estimate cell concentration and quantitatively detect differences in the microstructure of 3-D collagen hydrogels. Additionally, the feasibility of an ultrasound elastography technique called Single Tracking Location Acoustic Radiation Force Impulse (STL-ARFI) imaging was demonstrated for estimating the shear moduli of 3-D engineered tissues. High-frequency ultrasound techniques can be easily integrated into sterile environments necessary for tissue engineering. Furthermore, these high-frequency quantitative ultrasound techniques can enable noninvasive, volumetric characterization of the structural, biological, and mechanical properties of engineered tissues during fabrication and post-implantation.

Ultrasound pretreatment for enhanced biogas production from olive mill wastewater.

PubMed

Oz, Nilgun Ayman; Uzun, Alev Cagla

2015-01-01

This study investigates applicability of low frequency ultrasound technology to olive mill wastewaters (OMWs) as a pretreatment step prior to anaerobic batch reactors to improve biogas production and methane yield. OMWs originating from three phase processes are characterized with high organic content and complex nature. The treatment of the wastewater is problematic and alternative treatment options should be investigated. In the first part of the study, OMW samples were subjected to ultrasound at a frequency of 20kHz with applied powers varying between 50 and 100W under temperature controlled conditions for different time periods in order to determine the most effective sonication conditions. The level of organic matter solubilization at ultrasound experiments was assessed by calculating the ratio of soluble chemical oxygen demand/total chemical oxygen demand (SCOD/TCOD). The results revealed that the optimum ultrasonic condition for diluted OMW is 20kHz, 0.4W/mL for 10min. The application of ultrasound to OMW increased SCOD/TCOD ratio from 0.59 to 0.79. Statistical analysis (Friedman's tests) show that ultrasound was significantly effective on diluted OMW (p<0.05) in terms of SCOD parameter, but not for raw OMW (p>0.05). For raw OMW, this increase has been found to be limited due to high concentration of suspended solids (SS). In the second part of the study, biogas and methane production rates of anaerobic batch reactor fed with the ultrasound pretreated OMW samples were compared with the results of control reactor fed with untreated OMW in order to determine the effect of sonication. A nonparametric statistical procedure, Mann-Whitney U test, was used to compare biogas and methane production from anaerobic batch reactors for control and ultrasound pretreated samples. Results showed that application of low frequency ultrasound to OMW significantly improved both biogas and methane production in anaerobic batch reactor fed with the wastewater (p<0.05). Anaerobic batch reactor fed with ultrasound pretreated diluted OMW produced approximately 20% more biogas and methane compared with the untreated one (control reactor). The overall results indicated that low frequency ultrasound pretreatment increased soluble COD in OMW and subsequently biogas production. Copyright © 2014 Elsevier B.V. All rights reserved.

Microbubble mediated dual-frequency high intensity focused ultrasound thrombolysis: An In vitro study

NASA Astrophysics Data System (ADS)

Suo, Dingjie; Jin, Zhiyang; Jiang, Xiaoning; Dayton, Paul A.; Jing, Yun

2017-01-01

High intensity focused ultrasound (HIFU) has recently emerged as a promising alternative approach for thrombolysis. However, the high acoustic energy required by HIFU could elicit thermal damage bioeffects, impeding the clinical translation of this technique. This paper investigates the use of dual-frequency focused ultrasound (DFFU) mediated by microbubbles (MBs) to minimize the acoustic power required for thrombolysis in vitro. It was found that MBs, with sufficient concentration, could significantly lower the power threshold for thrombolysis for both DFFU and single-frequency focused ultrasound (SFFU). In addition, SFFU needs about 96%-156% higher energy to achieve the same thrombolysis efficiency as that of DFFU. The thrombolysis efficiency is also found to increase with the duty cycle. The measured cavitation signals reveal that the enhanced inertial cavitation is likely responsible for the improved thrombolysis under DFFU and MBs.

Crossed SMPS MOSFET-based protection circuit for high frequency ultrasound transceivers and transducers

PubMed Central

2014-01-01

Background The ultrasonic transducer is one of the core components of ultrasound systems, and the transducer’s sensitivity is significantly related the loss of electronic components such as the transmitter, receiver, and protection circuit. In an ultrasonic device, protection circuits are commonly used to isolate the electrical noise between an ultrasound transmitter and transducer and to minimize unwanted discharged pulses in order to protect the ultrasound receiver. However, the performance of the protection circuit and transceiver obviously degrade as the operating frequency or voltage increases. We therefore developed a crossed SMPS (Switching Mode Power Supply) MOSFET-based protection circuit in order to maximize the sensitivity of high frequency transducers in ultrasound systems. The high frequency pulse signals need to trigger the transducer, and high frequency pulse signals must be received by the transducer. We therefore selected the SMPS MOSFET, which is the main component of the protection circuit, to minimize the loss in high frequency operation. The crossed configuration of the protection circuit can drive balanced bipolar high voltage signals from the pulser and transfer the balanced low voltage echo signals from the transducer. Methods The equivalent circuit models of the SMPS MOSFET-based protection circuit are shown in order to select the proper device components. The schematic diagram and operation mechanism of the protection circuit is provided to show how the protection circuit is constructed. The P-Spice circuit simulation was also performed in order to estimate the performance of the crossed MOSFET-based protection circuit. Results We compared the performance of our crossed SMPS MOSFET-based protection circuit with a commercial diode-based protection circuit. At 60 MHz, our expander and limiter circuits have lower insertion loss than the commercial diode-based circuits. The pulse-echo test is typical method to evaluate the sensitivity of ultrasonic transducers. Therefore, we performed a pulse-echo test using a single element transducer in order to utilize the crossed SMPS MOSFET-based protection circuit in an ultrasound system. Conclusions The SMPS-based protection circuit could be a viable alternative that provides better sensitivity, especially for high frequency ultrasound applications. PMID:24924595

Crossed SMPS MOSFET-based protection circuit for high frequency ultrasound transceivers and transducers.

PubMed

Choi, Hojong; Shung, K Kirk

2014-06-12

The ultrasonic transducer is one of the core components of ultrasound systems, and the transducer's sensitivity is significantly related the loss of electronic components such as the transmitter, receiver, and protection circuit. In an ultrasonic device, protection circuits are commonly used to isolate the electrical noise between an ultrasound transmitter and transducer and to minimize unwanted discharged pulses in order to protect the ultrasound receiver. However, the performance of the protection circuit and transceiver obviously degrade as the operating frequency or voltage increases. We therefore developed a crossed SMPS (Switching Mode Power Supply) MOSFET-based protection circuit in order to maximize the sensitivity of high frequency transducers in ultrasound systems.The high frequency pulse signals need to trigger the transducer, and high frequency pulse signals must be received by the transducer. We therefore selected the SMPS MOSFET, which is the main component of the protection circuit, to minimize the loss in high frequency operation. The crossed configuration of the protection circuit can drive balanced bipolar high voltage signals from the pulser and transfer the balanced low voltage echo signals from the transducer. The equivalent circuit models of the SMPS MOSFET-based protection circuit are shown in order to select the proper device components. The schematic diagram and operation mechanism of the protection circuit is provided to show how the protection circuit is constructed. The P-Spice circuit simulation was also performed in order to estimate the performance of the crossed MOSFET-based protection circuit. We compared the performance of our crossed SMPS MOSFET-based protection circuit with a commercial diode-based protection circuit. At 60 MHz, our expander and limiter circuits have lower insertion loss than the commercial diode-based circuits. The pulse-echo test is typical method to evaluate the sensitivity of ultrasonic transducers. Therefore, we performed a pulse-echo test using a single element transducer in order to utilize the crossed SMPS MOSFET-based protection circuit in an ultrasound system. The SMPS-based protection circuit could be a viable alternative that provides better sensitivity, especially for high frequency ultrasound applications.

Dual-frequency ultrasound imaging and therapeutic bilaminar array using frequency selective isolation layer.

PubMed

Azuma, Takashi; Ogihara, Makoto; Kubota, Jun; Sasaki, Akira; Umemura, Shin-ichiro; Furuhata, Hiroshi

2010-05-01

A new ultrasound array transducer with two different optimal frequencies designed for diagnosis and therapy integration in Doppler imaging-based transcranial sonothrombolysis is described. Previous studies have shown that respective frequencies around 0.5 and 2 MHz are suitable for sonothrombolysis and Doppler imaging. Because of the small acoustic window available for transcranial ultrasound exposure, it is highly desirable that both therapeutic and diagnostic ultrasounds pass through the same aperture with high efficiency. To achieve such a dual-frequency array transducer, we propose a bilaminar array, having an array for imaging and another for therapy, with a frequency selective isolation layer between the two arrays. The function of this layer is to isolate the imaging array from the therapy array at 2 MHz without disturbing the 0.5-MHz ultrasound transmission. In this study, we first used a 1-D model including two lead zirconate titanate (PZT) layers separated by an isolation layer for intuitive understanding of the phenomena. After that, we optimized the acoustic impedance and thickness of the isolation layer by analyzing pulse propagation in a 2-D model by conducting a numerical simulation with commercially available software. The optimal acoustic impedance and thickness are 3 to 4 MRayI and lambda/10, respectively. On the basis of the optimization, a prototype array transducer was fabricated, and the spatial resolutions of the Doppler images it obtained were found to be practically the same as those obtained through conventional imaging array transducers.

Vibro-acoustography and multifrequency image compounding.

PubMed

Urban, Matthew W; Alizad, Azra; Fatemi, Mostafa

2011-08-01

Vibro-acoustography is an ultrasound based imaging modality that can visualize normal and abnormal soft tissue through mapping the acoustic response of the object to a harmonic radiation force at frequency Δf induced by focused ultrasound. In this method, the ultrasound energy is converted from high ultrasound frequencies to a low acoustic frequency (acoustic emission) that is often two orders of magnitude smaller than the ultrasound frequency. The acoustic emission is normally detected by a hydrophone. Depending on the setup, this low frequency sound may reverberate by object boundaries or other structures present in the acoustic paths before it reaches the hydrophone. This effect produces an artifact in the image in the form of gradual variations in image intensity that may compromise image quality. The use of tonebursts with finite length yields acoustic emission at Δf and at sidebands centered about Δf. Multiple images are formed by selectively applying bandpass filters on the acoustic emission at Δf and the associated sidebands. The data at these multiple frequencies are compounded through both coherent and incoherent processes to reduce the acoustic emission reverberation artifacts. Experimental results from a urethane breast phantom are described. The coherent and incoherent compounding of multifrequency data show, both qualitatively and quantitatively, the efficacy of this reverberation reduction method. This paper presents theory describing the physical origin of this artifact and use of image data created using multifrequency vibro-acoustography for reducing reverberation artifacts. Copyright © 2011 Elsevier B.V. All rights reserved.

Vibro-acoustography and Multifrequency Image Compounding

PubMed Central

Urban, Matthew W.; Alizad, Azra; Fatemi, Mostafa

2011-01-01

Vibro-acoustography is an ultrasound based imaging modality that can visualize normal and abnormal soft tissue through mapping the acoustic response of the object to a harmonic radiation force at frequency Δf induced by focused ultrasound. In this method, the ultrasound energy is converted from high ultrasound frequencies to a low acoustic frequency (acoustic emission) that is often two orders of magnitude smaller than the ultrasound frequency. The acoustic emission is normally detected by a hydrophone. Depending on the setup, this low frequency sound may reverberate by object boundaries or other structures present in the acoustic paths before it reaches the hydrophone. This effect produces an artifact in the image in the form of gradual variations in image intensity that may compromise image quality. The use of tonebursts with finite length yields acoustic emission at Δf and at sidebands centered about Δf. Multiple images are formed by selectively applying bandpass filters on the acoustic emission at Δf and the associated sidebands. The data at these multiple frequencies are compounded through both coherent and incoherent processes to reduce the acoustic emission reverberation artifacts. Experimental results from a urethane breast phantom are described. The coherent and incoherent compounding of multifrequency data show, both qualitatively and quantitatively, the efficacy of this reverberation reduction method. This paper presents theory describing the physical origin of this artifact and use of image data created using multifrequency vibro-acoustography for reducing reverberation artifacts. PMID:21377181

The Mobile Laboratory for Radio-Frequency Interference Monitoring at the Sardinia Radio Telescope

NASA Astrophysics Data System (ADS)

Bolli, Pietro; Gaudiomonte, Francesco; Ambrosini, Roberto; Bortolotti, Claudio; Roma, Mauro; Barberi, Carlo; Piccoli, Fabrizio

2013-10-01

In this paper, a quite unique mobile laboratory for monitoring radio-frequency interference with a radio-astronomical observatory is described. The unit is fully operational at the new Sardinia Radio Telescope, a 64-m antenna now in the commissioning phase in Italy. The mobile laboratory is mainly used to identify the source of interference with the radio astronomy service using iterative triangulations in the azimuth directions. Both the design and realization of this prototype were handled with outstanding care to limit the emission of self-interference as much as possible. The laboratory was equipped with excellent microwave instruments in terms of sensitivity, frequency coverage, dynamic range, and various demodulation and signal-analysis facilities. The unit can be quickly switched to different RF and power-supply configurations, while offering operators a safe and efficient workplace, even in adverse meteorological and driving conditions. In the past months, the mobile laboratory has proven to be successful in detecting and identifying many radio interferers. Two examples of measurement campaigns are described.

Interplanetary radio storms. II - Emission levels and solar wind speed in the range 0.05-0.8 AU

NASA Technical Reports Server (NTRS)

Bougeret, J.-L.; Fainberg, J.; Stone, R. G.

1984-01-01

Storms of interplanetary type III radio bursts (IP storms) are commonly observed in the interplanetary medium by the ISEE-3 radio instrument. This instrument has the capability of accurately determining the arrival direction of the radio emission. At each observing frequency, the storm radio sources are tracked as they cross the line-of-sight to the sun. Using a simple model, the emission levels are determined at a number of radio frequencies for four separate storms. The IP storm radiation is found to occur in regions of enhanced density at levels of 0.05 to 0.8 AU. The density in these enhancements falls off faster than R(-2). The solar wind speed in the storm region is also measured. The analysis is consistent with steady conditions in the storm region during a few days around the III storm burst radio emission at the harmonic of the local plasma frequency.

Coherent curvature radiation and fast radio bursts

NASA Astrophysics Data System (ADS)

Ghisellini, Gabriele; Locatelli, Nicola

2018-06-01

Fast radio bursts are extragalactic radio transient events lasting a few milliseconds with a Jy flux at 1 GHz. We propose that these properties suggest a neutron star progenitor, and focus on coherent curvature radiation as the radiation mechanism. We study for which sets of parameters the emission can fulfil the observational constraints. Even if the emission is coherent, we find that self-absorption can limit the produced luminosities at low radio frequencies and that an efficient re-acceleration process is needed to balance the dramatic energy losses of the emitting particles. Self-absorption limits the luminosities at low radio frequency, while coherence favours steep optically thin spectra. Furthermore, the magnetic geometry must have a high degree of order to obtain coherent curvature emission. Particles emit photons along their velocity vectors, thereby greatly reducing the inverse Compton mechanism. In this case we predict that fast radio bursts emit most of their luminosities in the radio band and have no strong counterpart in any other frequency bands.

tf_unet: Generic convolutional neural network U-Net implementation in Tensorflow

NASA Astrophysics Data System (ADS)

Akeret, Joel; Chang, Chihway; Lucchi, Aurelien; Refregier, Alexandre

2016-11-01

tf_unet mitigates radio frequency interference (RFI) signals in radio data using a special type of Convolutional Neural Network, the U-Net, that enables the classification of clean signal and RFI signatures in 2D time-ordered data acquired from a radio telescope. The code is not tied to a specific segmentation and can be used, for example, to detect radio frequency interference (RFI) in radio astronomy or galaxies and stars in widefield imaging data. This U-Net implementation can outperform classical RFI mitigation algorithms.

Calculus, Radio Dials and the Straight-Line Frequency Variable Capacitor

ERIC Educational Resources Information Center

Boyadzhiev, Khristo N.

2010-01-01

Most often radio dials of analogue radios are not uniformly graded; the frequencies are cramped on the left side or on the right side. This makes tuning more difficult. Why are dials made this way? We shall see here that simple calculus can help understand this problem and solve it. (Contains 7 figures.)

75 FR 9850 - Tank Level Probing Radars in the Frequency Band 77-81 GHz

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-04

... National Radio Astronomy Observatory (NRAO) states that it would not object to the Ohmart/VEGA waiver if it Frequency Band of Operation. Authorized operations in the 77-81 GHz band currently include radio astronomy... operations in this band would have on authorized services. Regarding radio astronomy, the Commission observes...

Frequency Allocation; The Radio Spectrum.

ERIC Educational Resources Information Center

Federal Communications Commission, Washington, DC.

The Federal Communications Commission (FCC) assigns segments of the radio spectrum to categories of users, and specific frequencies within each segment to individual users. Since demand for channel space exceeds supply, the process is complex. The radio spectrum can be compared to a long ruler: the portion from 10-540 kiloHertz has been set aside…

BLAZAR SPECTRAL PROPERTIES AT 74 MHz

DOE Office of Scientific and Technical Information (OSTI.GOV)

Massaro, F.; Funk, S.; Giroletti, M.

2013-10-01

Blazars are the most extreme class of active galactic nuclei. Despite a previous investigation at 102 MHz for a small sample of BL Lac objects and our recent analysis of blazars detected in the Westerbork Northern Sky Survey, a systematic study of the blazar spectral properties at frequencies below 100 MHz has been never carried out. In this paper, we present the first analysis of the radio spectral behavior of blazars based on the recent Very Large Array Low-frequency Sky Survey (VLSS) at 74 MHz. We search for blazar counterparts in the VLSS catalog, confirming that they are detected atmore » 74 MHz. We then show that blazars present radio-flat spectra (i.e., radio spectral indices of ∼0.5) when evaluated, which also about an order of magnitude in frequency lower than previous analyses. Finally, we discuss the implications of our findings in the context of the blazars-radio galaxies connection since the low-frequency radio data provide a new diagnostic tool to verify the expectations of the unification scenario for radio-loud active galaxies.« less

The use of 5-fluorouracil-loaded nanobubbles combined with low-frequency ultrasound to treat hepatocellular carcinoma in nude mice.

PubMed

Li, Qiaoya; Li, Hongyang; He, Chengjun; Jing, Zhouhong; Liu, Changan; Xie, Juan; Ma, Wenwen; Deng, Huisheng

2017-11-21

This study aimed to investigate the therapeutic effects of 5-fluorouracil (5-FU)-loaded nanobubbles irradiated with low-intensity, low-frequency ultrasound in nude mice with hepatocellular carcinoma (HCC). A transplanted tumor model of HCC in nude mice was established in 40 mice, which were then randomly divided equally into four groups: group A (saline), group B (5-FU-loaded nanobubbles), group C (5-FU-loaded nanobubbles with non-low-frequency ultrasound), and group D (5-FU-loaded nanobubbles with low-frequency ultrasound). The tumor size in each mouse was observed via ultrasound before and after the treatments. Inhibition of the tumor growth in each group was compared, and survival curves were generated. Tumor tissues were removed to determine the apoptotic index using the TUNEL method and quantitative analysis. Tumor tissues with CD34-positive microvessels were observed by immunohistochemistry, and the tumor microvessel densities were calculated. The growth rate of the tumor volumes in group D was significantly slower than that in the other groups, while the tumor inhibition rates and apoptotic index in group D were significantly higher than those of the other groups. The number of microvessels staining positive for CD34 was decreased in group D. Therefore, group D presented the most significant inhibitory effects. Therefore, 5-FU-loaded nanobubbles subjected to irradiation with low-frequency ultrasound could further improve drug targeting and effectively inhibit the growth of transplanted tumors, which is expected to become an ideal drug carrier and targeted drug delivery system for the treatment of HCC in the future.

47 CFR 74.503 - Frequency selection.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 4 2010-10-01 2010-10-01 false Frequency selection. 74.503 Section 74.503 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES EXPERIMENTAL RADIO... § 74.503 Frequency selection. (a) Each application for a new station or change in an existing station...

Radio-frequency reflectometry on an undoped AlGaAs/GaAs single electron transistor

DOE Office of Scientific and Technical Information (OSTI.GOV)

MacLeod, S. J.; See, A. M.; Keane, Z. K.

2014-01-06

Radio frequency reflectometry is demonstrated in a sub-micron undoped AlGaAs/GaAs device. Undoped single electron transistors (SETs) are attractive candidates to study single electron phenomena, due to their charge stability and robust electronic properties after thermal cycling. However, these devices require a large top-gate, which is unsuitable for the fast and sensitive radio frequency reflectometry technique. Here, we demonstrate that rf reflectometry is possible in an undoped SET.

Conveyorized Radio Frequency Cure of Epoxy Glass Composites.

DTIC Science & Technology

1980-05-01

a conveyorized radio frequency oven. The conveyorized radio frequency 20-kilowatt (90-100 megahertz) dielectric heater was de - designed and...Process were de - termined with reference to property requirements specified in Table three of 8MS-8-196A. Although the BM-8,196A relates to material...requirements of the 8MS and agree with the values contained in the 3M certifying report. De - tailed test results are presented as Appendix J. In addition

Low-amplitude non-linear volume vibrations of single microbubbles measured with an "acoustical camera".

PubMed

Renaud, Guillaume; Bosch, Johan G; Van Der Steen, Antonius F W; De Jong, Nico

2014-06-01

Contrast-enhanced ultrasound imaging is based on the detection of non-linear vibrational responses of a contrast agent after its intravenous administration. Improving contrast-enhanced images requires an accurate understanding of the vibrational response to ultrasound of the lipid-coated gas microbubbles that constitute most ultrasound contrast agents. Variations in the volume of microbubbles provide the most efficient radiation of ultrasound and, therefore, are the most important bubble vibrations for medical diagnostic ultrasound imaging. We developed an "acoustical camera" that measures the dynamic volume change of individual microbubbles when excited by a pressure wave. In the work described here, the technique was applied to the characterization of low-amplitude non-linear behaviors of BR14 microbubbles (Bracco Research, Geneva, Switzerland). The amplitude dependence of the resonance frequency and the damping, the prevalence of efficient subharmonic and ultraharmonic vibrations and the amplitude dependence of the response at the fundamental frequency and at the second harmonic frequency were investigated. Because of the large number of measurements, we provide a statistical characterization of the low-amplitude non-linear properties of the contrast agent. Copyright © 2014 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

Investigation of optimal method for inducing harmonic motion in tissue using a linear ultrasound phased array--a simulation study.

PubMed

Heikkilä, Janne; Hynynen, Kullervo

2006-04-01

Many noninvasive ultrasound techniques have been developed to explore mechanical properties of soft tissues. One of these methods, Localized Harmonic Motion Imaging (LHMI), has been proposed to be used for ultrasound surgery monitoring. In LHMI, dynamic ultrasound radiation-force stimulation induces displacements in a target that can be measured using pulse-echo imaging and used to estimate the elastic properties of the target. In this initial, simulation study, the use of a one-dimensional phased array is explored for the induction of the tissue motion. The study compares three different dual-frequency and amplitude-modulated single-frequency methods for the inducing tissue motion. Simulations were computed in a homogeneous soft-tissue volume. The Rayleigh integral was used in the simulations of the ultrasound fields and the tissue displacements were computed using a finite-element method (FEM). The simulations showed that amplitude-modulated sonication using a single frequency produced the largest vibration amplitude of the target tissue. These simulations demonstrate that the properties of the tissue motion are highly dependent on the sonication method and that it is important to consider the full three-dimensional distribution of the ultrasound field for controlling the induction of tissue motion.

Fusion of radar and ultrasound sensors for concealed weapons detection

NASA Astrophysics Data System (ADS)

Felber, Franklin S.; Davis, Herbert T., III; Mallon, Charles E.; Wild, Norbert C.

1996-06-01

An integrated radar and ultrasound sensor, capable of remotely detecting and imaging concealed weapons, is being developed. A modified frequency-agile, mine-detection radar is intended to specify with high probability of detection at ranges of 1 to 10 m which individuals in a moving crowd may be concealing metallic or nonmetallic weapons. Within about 1 to 5 m, the active ultrasound sensor is intended to enable a user to identify a concealed weapon on a moving person with low false-detection rate, achieved through a real-time centimeter-resolution image of the weapon. The goal for sensor fusion is to have the radar acquire concealed weapons at long ranges and seamlessly hand over tracking data to the ultrasound sensor for high-resolution imaging on a video monitor. We have demonstrated centimeter-resolution ultrasound images of metallic and non-metallic weapons concealed on a human at ranges over 1 m. Processing of the ultrasound images includes filters for noise, frequency, brightness, and contrast. A frequency-agile radar has been developed by JAYCOR under the U.S. Army Advanced Mine Detection Radar Program. The signature of an armed person, detected by this radar, differs appreciably from that of the same person unarmed.

Passive Wearable Skin Patch Sensor Measures Limb Hemodynamics Based on Electromagnetic Resonance.

PubMed

Cluff, Kim; Becker, Ryan; Jayakumar, Balakumar; Han, Kiyun; Condon, Ernie; Dudley, Kenneth; Szatkowski, George; Pipinos, Iraklis I; Amick, Ryan Z; Patterson, Jeremy

2018-04-01

The objectives of this study were to design and develop an open-circuit electromagnetic resonant skin patch sensor, characterize the fluid volume and resonant frequency relationship, and investigate the sensor's ability to measure limb hemodynamics and pulse volume waveform features. The skin patch was designed from an open-circuit electromagnetic resonant sensor comprised of a single baseline trace of copper configured into a square planar spiral which had a self-resonating response when excited by an external radio frequency sweep. Using a human arm phantom with a realistic vascular network, the sensor's performance to measure limb hemodynamics was evaluated. The sensor was able to measure pulsatile blood flow which registered as shifts in the sensor's resonant frequencies. The time-varying waveform pattern of the resonant frequency displayed a systolic upstroke, a systolic peak, a dicrotic notch, and a diastolic down stroke. The resonant frequency waveform features and peak systolic time were validated against ultrasound pulse wave Doppler. A statistical correlation analysis revealed a strong correlation () between the resonant sensor peak systolic time and the pulse wave Doppler peak systolic time. The sensor was able to detect pulsatile flow, identify hemodynamic waveform features, and measure heart rate with 98% accuracy. The open-circuit resonant sensor design leverages the architecture of a thin planar spiral which is passive (does not require batteries), robust and lightweight (does not have electrical components or electrical connections), and may be able to wirelessly monitor cardiovascular health and limb hemodynamics.

Momentum-resolved radio-frequency spectroscopy of a spin-orbit-coupled atomic Fermi gas near a Feshbach resonance in harmonic traps

NASA Astrophysics Data System (ADS)

Peng, Shi-Guo; Liu, Xia-Ji; Hu, Hui; Jiang, Kaijun

2012-12-01

We theoretically investigate the momentum-resolved radio-frequency spectroscopy of a harmonically trapped atomic Fermi gas near a Feshbach resonance in the presence of equal Rashba and Dresselhaus spin-orbit coupling. The system is qualitatively modeled as an ideal gas mixture of atoms and molecules, in which the properties of molecules, such as the wave function, binding energy, and effective mass, are determined from the two-particle solution of two interacting atoms. We calculate separately the radio-frequency response from atoms and molecules at finite temperatures by using the standard Fermi golden rule and take into account the effect of harmonic traps within local density approximation. The total radio-frequency spectroscopy is discussed as functions of temperature and spin-orbit coupling strength. Our results give a qualitative picture of radio-frequency spectroscopy of a resonantly interacting spin-orbit-coupled Fermi gas and can be directly tested in atomic Fermi gases of 40K atoms at Shanxi University and 6Li atoms at the Massachusetts Institute of Technology.

RF lockout circuit for electronic locking system

NASA Astrophysics Data System (ADS)

Becker, Earl M., Jr.; Miller, Allen

1991-02-01

An electronics lockout circuit was invented that includes an antenna adapted to receive radio frequency signals from a transmitter, and a radio frequency detector circuit which converts the radio frequency signals into a first direct current voltage indicative of the relative strength of the field resulting from the radio frequency signals. The first direct current voltage is supplied to a trigger circuit which compares this direct current voltage to an adjustable direct current reference voltage. This provides a second direct current voltage at the output whenever the amplitude of the first direct current voltage exceeds the amplitude of the reference voltage provided by the comparator circuit. This is supplied to a disconnect relay circuit which, upon receiving a signal from the electronic control unit of an electronic combination lock during the time period at which the second direct current voltage is present, isolates the door strike coil of a security door from the electronic control unit. This prevents signals falsely generated by the electronic control unit because of radio frequency signals in the vicinity of the electronic control unit energizing the door strike coil and accidentally opening a security door.

Methods for magnetic resonance analysis using magic angle technique

DOEpatents

Hu, Jian Zhi [Richland, WA; Wind, Robert A [Kennewick, WA; Minard, Kevin R [Kennewick, WA; Majors, Paul D [Kennewick, WA

2011-11-22

Methods of performing a magnetic resonance analysis of a biological object are disclosed that include placing the object in a main magnetic field (that has a static field direction) and in a radio frequency field; rotating the object at a frequency of less than about 100 Hz around an axis positioned at an angle of about 54.degree.44' relative to the main magnetic static field direction; pulsing the radio frequency to provide a sequence that includes a phase-corrected magic angle turning pulse segment; and collecting data generated by the pulsed radio frequency. In particular embodiments the method includes pulsing the radio frequency to provide at least two of a spatially selective read pulse, a spatially selective phase pulse, and a spatially selective storage pulse. Further disclosed methods provide pulse sequences that provide extended imaging capabilities, such as chemical shift imaging or multiple-voxel data acquisition.

Modelling and mitigating refractive propagation effects in precision pulsar timing observations

NASA Astrophysics Data System (ADS)

Shannon, R. M.; Cordes, J. M.

2017-01-01

To obtain the most accurate pulse arrival times from radio pulsars, it is necessary to correct or mitigate the effects of the propagation of radio waves through the warm and ionized interstellar medium. We examine both the strength of propagation effects associated with large-scale electron-density variations and the methodology used to estimate infinite frequency arrival times. Using simulations of two-dimensional phase-varying screens, we assess the strength and non-stationarity of timing perturbations associated with large-scale density variations. We identify additional contributions to arrival times that are stochastic in both radio frequency and time and therefore not amenable to correction solely using times of arrival. We attribute this to the frequency dependence of the trajectories of the propagating radio waves. We find that this limits the efficacy of low-frequency (metre-wavelength) observations. Incorporating low-frequency pulsar observations into precision timing campaigns is increasingly problematic for pulsars with larger dispersion measures.

Direct measurement of axial momentum imparted by an electrothermal radiofrequency plasma micro-thruster

NASA Astrophysics Data System (ADS)

Charles, Christine; Boswell, Roderick; Bish, Andrew; Khayms, Vadim; Scholz, Edwin

2016-05-01

Gas flow heating using radio frequency plasmas offers the possibility of depositing power in the centre of the flow rather than on the outside, as is the case with electro-thermal systems where thermal wall losses lower efficiency. Improved systems for space propulsion are one possible application and we have tested a prototype micro-thruster on a thrust balance in vacuum. For these initial tests, a fixed component radio frequency matching network weighing 90 grams was closely attached to the thruster in vacuum with the frequency agile radio frequency generator power being delivered via a 50 Ohm cable. Without accounting for system losses (estimated at around 50%), for a few 10s of Watts from the radio frequency generator the specific impulse was tripled to ˜48 seconds and the thrust tripled from 0.8 to 2.4 milli-Newtons.

Articular cartilage degeneration classification by means of high-frequency ultrasound.

PubMed

Männicke, N; Schöne, M; Oelze, M; Raum, K

2014-10-01

To date only single ultrasound parameters were regarded in statistical analyses to characterize osteoarthritic changes in articular cartilage and the potential benefit of using parameter combinations for characterization remains unclear. Therefore, the aim of this work was to utilize feature selection and classification of a Mankin subset score (i.e., cartilage surface and cell sub-scores) using ultrasound-based parameter pairs and investigate both classification accuracy and the sensitivity towards different degeneration stages. 40 punch biopsies of human cartilage were previously scanned ex vivo with a 40-MHz transducer. Ultrasound-based surface parameters, as well as backscatter and envelope statistics parameters were available. Logistic regression was performed with each unique US parameter pair as predictor and different degeneration stages as response variables. The best ultrasound-based parameter pair for each Mankin subset score value was assessed by highest classification accuracy and utilized in receiver operating characteristics (ROC) analysis. The classifications discriminating between early degenerations yielded area under the ROC curve (AUC) values of 0.94-0.99 (mean ± SD: 0.97 ± 0.03). In contrast, classifications among higher Mankin subset scores resulted in lower AUC values: 0.75-0.91 (mean ± SD: 0.84 ± 0.08). Variable sensitivities of the different ultrasound features were observed with respect to different degeneration stages. Our results strongly suggest that combinations of high-frequency ultrasound-based parameters exhibit potential to characterize different, particularly very early, degeneration stages of hyaline cartilage. Variable sensitivities towards different degeneration stages suggest that a concurrent estimation of multiple ultrasound-based parameters is diagnostically valuable. In-vivo application of the present findings is conceivable in both minimally invasive arthroscopic ultrasound and high-frequency transcutaneous ultrasound. Copyright © 2014 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.

47 CFR 73.682 - TV transmission standards.

Code of Federal Regulations, 2012 CFR

2012-10-01

....682 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES RADIO... frequency shall be nominally 1.25 MHz above the lower boundary of the channel. (3) The aural center frequency shall be 4.5 MHz higher than the visual carrier frequency. (4) The visual transmission amplitude...

47 CFR 73.682 - TV transmission standards.

Code of Federal Regulations, 2011 CFR

2011-10-01

....682 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES RADIO... frequency shall be nominally 1.25 MHz above the lower boundary of the channel. (3) The aural center frequency shall be 4.5 MHz higher than the visual carrier frequency. (4) The visual transmission amplitude...

47 CFR 73.682 - TV transmission standards.

Code of Federal Regulations, 2013 CFR

2013-10-01

....682 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES RADIO... frequency shall be nominally 1.25 MHz above the lower boundary of the channel. (3) The aural center frequency shall be 4.5 MHz higher than the visual carrier frequency. (4) The visual transmission amplitude...

47 CFR 73.682 - TV transmission standards.

Code of Federal Regulations, 2014 CFR

2014-10-01

....682 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES RADIO... frequency shall be nominally 1.25 MHz above the lower boundary of the channel. (3) The aural center frequency shall be 4.5 MHz higher than the visual carrier frequency. (4) The visual transmission amplitude...

47 CFR 73.682 - TV transmission standards.

Code of Federal Regulations, 2010 CFR

2010-10-01

....682 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES RADIO... frequency shall be nominally 1.25 MHz above the lower boundary of the channel. (3) The aural center frequency shall be 4.5 MHz higher than the visual carrier frequency. (4) The visual transmission amplitude...

Optical micromachined ultrasound transducers (OMUT)--a new approach for high-frequency transducers.

PubMed

Tadayon, Mohammad Amin; Ashkenazi, Shai

2013-09-01

The sensitivity and reliability of piezoelectric ultrasound transducers severely degrade in applications requiring high frequency and small element size. Alternative technologies such as capacitive micromachined ultrasound transducers (CMUT) and optical sensing and generation of ultrasound have been proposed and studied for several decades. In this paper, we present a new type of device based on optical micromachined ultrasound transducer (OMUT) technology. OMUTs rely on microfabrication techniques to construct micrometerscale air cavities capped by an elastic membrane. A modified photoresist bonding process has been developed to facilitate the fabrication of these devices. We will describe the design, fabrication, and testing of prototype OMUT devices which implement a receive-only function. Future design modifications are proposed for incorporating complete transmit¿receive functionality in a single element.

Comparison of morphology and phase composition of hydroxyapatite nanoparticles sonochemically synthesized with dual- or single-frequency ultrasonic reactor

NASA Astrophysics Data System (ADS)

Deng, Shi-ting; Yu, Hong; Liu, Di; Bi, Yong-guang

2017-10-01

To investigate how a dual- or single-frequency ultrasonic reactor changes the morphology and phase composition of hydroxyapatite nanoparticles (nHAPs), we designed and constructed the preparation of nHAPs using dual- or single-frequency ultrasonic devices, i.e., the single frequency ultrasonic generator with ultrasonic horn (25 kHz), the ultrasonic bath (40 kHz) and the dual-frequency sonochemical systems combined with the ultrasonic horn and the ultrasonic bath simultaneously (25 + 40 kHz). The results showed that the sonicated samples displayed a more uniform shape with less agglomeration than non-sonicated sample. The rod-shaped particles with 1.66 stoichiometry and without a second phase were synthesized successfully in the ultrasonic bath or horn systems. The nHAPs obtained from the dual-frequency ultrasonic systems exhibited a regular rod-shaped structure with better dispersion and more uniform shapes than those of obtained in either ultrasonic bath or horn systems. Additionally, the size of rod-shaped particles obtained in the dual-frequency ultrasound with a mean width of 35 nm and a mean length of 64 nm was smaller than other samples. A possible mechanism is that the dual-frequency ultrasound significantly enhances the cavitation yield over single frequency ultrasound and thus improves the dispersion of particles and reduces the size of the crystals. In addition, irregular holes can be observed in the nanoparticles obtained in the dual-frequency ultrasound. Therefore, the dual-frequency ultrasonic systems are expected to become a convenient, efficient and environmentally friendly synthetic technology to obtain well-defined nHAPs for specific biomedical applications.

The Contribution of "Around the Dial" to American Music Radio Announcing Culture.

ERIC Educational Resources Information Center

Shields, Steven O.; Ogles, Robert M.

Shared conventions of the modern radio industry should allow radio announcers and other producers of radio content to distinguish "good radio" from "bad radio." To help in making this distinction, a study delineated some of the basic conventions used in the production of radio content and analyzed the frequency of their…

Spatial-temporal three-dimensional ultrasound plane-by-plane active cavitation mapping for high-intensity focused ultrasound in free field and pulsatile flow.

PubMed

Ding, Ting; Hu, Hong; Bai, Chen; Guo, Shifang; Yang, Miao; Wang, Supin; Wan, Mingxi

2016-07-01

Cavitation plays important roles in almost all high-intensity focused ultrasound (HIFU) applications. However, current two-dimensional (2D) cavitation mapping could only provide cavitation activity in one plane. This study proposed a three-dimensional (3D) ultrasound plane-by-plane active cavitation mapping (3D-UPACM) for HIFU in free field and pulsatile flow. The acquisition of channel-domain raw radio-frequency (RF) data in 3D space was performed by sequential plane-by-plane 2D ultrafast active cavitation mapping. Between two adjacent unit locations, there was a waiting time to make cavitation nuclei distribution of the liquid back to the original state. The 3D cavitation map equivalent to the one detected at one time and over the entire volume could be reconstructed by Marching Cube algorithm. Minimum variance (MV) adaptive beamforming was combined with coherence factor (CF) weighting (MVCF) or compressive sensing (CS) method (MVCS) to process the raw RF data for improved beamforming or more rapid data processing. The feasibility of 3D-UPACM was demonstrated in tap-water and a phantom vessel with pulsatile flow. The time interval between temporal evolutions of cavitation bubble cloud could be several microseconds. MVCF beamformer had a signal-to-noise ratio (SNR) at 14.17dB higher, lateral and axial resolution at 2.88times and 1.88times, respectively, which were compared with those of B-mode active cavitation mapping. MVCS beamformer had only 14.94% time penalty of that of MVCF beamformer. This 3D-UPACM technique employs the linear array of a current ultrasound diagnosis system rather than a 2D array transducer to decrease the cost of the instrument. Moreover, although the application is limited by the requirement for a gassy fluid medium or a constant supply of new cavitation nuclei that allows replenishment of nuclei between HIFU exposures, this technique may exhibit a useful tool in 3D cavitation mapping for HIFU with high speed, precision and resolution, especially in a laboratory environment where more careful analysis may be required under controlled conditions. Copyright © 2016 Elsevier B.V. All rights reserved.

SU-D-210-05: The Accuracy of Raw and B-Mode Image Data for Ultrasound Speckle Tracking in Radiation Therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

O’Shea, T; Bamber, J; Harris, E

Purpose: For ultrasound speckle tracking there is some evidence that the envelope-detected signal (the main step in B-mode image formation) may be more accurate than raw ultrasound data for tracking larger inter-frame tissue motion. This study investigates the accuracy of raw radio-frequency (RF) versus non-logarithmic compressed envelope-detected (B-mode) data for ultrasound speckle tracking in the context of image-guided radiation therapy. Methods: Transperineal ultrasound RF data was acquired (with a 7.5 MHz linear transducer operating at a 12 Hz frame rate) from a speckle phantom moving with realistic intra-fraction prostate motion derived from a commercial tracking system. A normalised cross-correlation templatemore » matching algorithm was used to track speckle motion at the focus using (i) the RF signal and (ii) the B-mode signal. A range of imaging rates (0.5 to 12 Hz) were simulated by decimating the imaging sequences, therefore simulating larger to smaller inter-frame displacements. Motion estimation accuracy was quantified by comparison with known phantom motion. Results: The differences between RF and B-mode motion estimation accuracy (2D mean and 95% errors relative to ground truth displacements) were less than 0.01 mm for stable and persistent motion types and 0.2 mm for transient motion for imaging rates of 0.5 to 12 Hz. The mean correlation for all motion types and imaging rates was 0.851 and 0.845 for RF and B-mode data, respectively. Data type is expected to have most impact on axial (Superior-Inferior) motion estimation. Axial differences were <0.004 mm for stable and persistent motion and <0.3 mm for transient motion (axial mean errors were lowest for B-mode in all cases). Conclusions: Using the RF or B-mode signal for speckle motion estimation is comparable for translational prostate motion. B-mode image formation may involve other signal-processing steps which also influence motion estimation accuracy. A similar study for respiratory-induced motion would also be prudent. This work is support by Cancer Research UK Programme Grant C33589/A19727.« less

Ultrasound assisted intensification of enzyme activity and its properties: a mini-review.

PubMed

Nadar, Shamraja S; Rathod, Virendra K

2017-08-22

Over the last decade, ultrasound technique has emerged as the potential technology which shows large applications in food and biotechnology processes. Earlier, ultrasound has been employed as a method of enzyme inactivation but recently, it has been found that ultrasound does not inactivate all enzymes, particularly, under mild conditions. It has been shown that the use of ultrasonic treatment at appropriate frequencies and intensity levels can lead to enhanced enzyme activity due to favourable conformational changes in protein molecules without altering its structural integrity. The present review article gives an overview of influence of ultrasound irradiation parameters (intensity, duty cycle and frequency) and enzyme related factors (enzyme concentration, temperature and pH) on the catalytic activity of enzyme during ultrasound treatment. Also, it includes the effect of ultrasound on thermal kinetic parameters and Michaelis-Menten kinetic parameters (k m and V max ) of enzymes. Further, in this review, the physical and chemical effects of ultrasound on enzyme have been correlated with thermodynamic parameters (enthalpy and entropy). Various techniques used for investigating the conformation changes in enzyme after sonication have been highlighted. At the end, different techniques of immobilization for ultrasound treated enzyme have been summarized.

Wave optics-based LEO-LEO radio occultation retrieval

NASA Astrophysics Data System (ADS)

Benzon, Hans-Henrik; Høeg, Per

2016-06-01

This paper describes the theory for performing retrieval of radio occultations that use probing frequencies in the XK and KM band. Normally, radio occultations use frequencies in the L band, and GPS satellites are used as the transmitting source, and the occultation signals are received by a GPS receiver on board a Low Earth Orbit (LEO) satellite. The technique is based on the Doppler shift imposed, by the atmosphere, on the signal emitted from the GPS satellite. Two LEO satellites are assumed in the occultations discussed in this paper, and the retrieval is also dependent on the decrease in the signal amplitude caused by atmospheric absorption. The radio wave transmitter is placed on one of these satellites, while the receiver is placed on the other LEO satellite. One of the drawbacks of normal GPS-based radio occultations is that external information is needed to calculate some of the atmospheric products such as the correct water vapor content in the atmosphere. These limitations can be overcome when a proper selected range of high-frequency waves are used to probe the atmosphere. Probing frequencies close to the absorption line of water vapor have been included, thus allowing the retrieval of the water vapor content. Selecting the correct probing frequencies would make it possible to retrieve other information such as the content of ozone. The retrieval is performed through a number of processing steps which are based on the Full Spectrum Inversion (FSI) technique. The retrieval chain is therefore a wave optics-based retrieval chain, and it is therefore possible to process measurements that include multipath. In this paper simulated LEO to LEO radio occultations based on five different frequencies are used. The five frequencies are placed in the XK or KM frequency band. This new wave optics-based retrieval chain is used on a number of examples, and the retrieved atmospheric parameters are compared to the parameters from a global European Centre for Medium-Range Weather Forecasts analysis model. This model is used in a forward propagator that simulates the electromagnetic field amplitudes and phases at the receiver on board the LEO satellite. LEO-LEO cross-link radio occultations using high frequencies are a relatively new technique, and the possibilities and advantages of the technique still need to be investigated. The retrieval of this type of radio occultations is considerably more complicated than standard GPS to LEO radio occultations, because the attenuation of the probing radio waves is used in the retrieval and the atmospheric parameters are found using a least squares solver. The best algorithms and the number of probing frequencies that is economically viable must also be determined. This paper intends to answer some of these questions using end-to-end simulations.

Pulsar-aided SETI experimental observations

NASA Technical Reports Server (NTRS)

Heidmann, J.; Biraud, F.; Tarter, J.

1989-01-01

The rotational frequencies of pulsars are used to select preferred radio frequencies for SETI. Pulsar rotational frequencies are converted into SETI frequencies in the 1-10 GHz Galactic radio window. Experimental observations using the frequencies are conducted for target stars closer than 25 parsecs, unknown targets in a globular cluster, and unknown targets in the Galaxy closer than 2.5 kpc. The status of these observations is discussed.

Low frequency radio synthesis imaging of the galactic center region

NASA Astrophysics Data System (ADS)

Nord, Michael Evans

2005-11-01

The Very Large Array radio interferometer has been equipped with new receivers to allow observations at 330 and 74 MHz, frequencies much lower than were previously possible with this instrument. Though the VLA dishes are not optimal for working at these frequencies, the system is successful and regular observations are now taken at these frequencies. However, new data analysis techniques are required to work at these frequencies. The technique of self- calibration, used to remove small atmospheric effects at higher frequencies, has been adapted to compensate for ionospheric turbulence in much the same way that adaptive optics is used in the optical regime. Faceted imaging techniques are required to compensate for the noncoplanar image distortion that affects the system due to the wide fields of view at these frequencies (~2.3° at 330 MHz and ~11° at 74 MHz). Furthermore, radio frequency interference is a much larger problem at these frequencies than in higher frequencies and novel approaches to its mitigation are required. These new techniques and new system are allowing for imaging of the radio sky at sensitivities and resolutions orders of magnitude higher than were possible with the low frequency systems of decades past. In this work I discuss the advancements in low frequency data techniques required to make high resolution, high sensitivity, large field of view measurements with the new Very Large Array low frequency system and then detail the results of turning this new system and techniques on the center of our Milky Way Galaxy. At 330 MHz I image the Galactic center region with roughly 10 inches resolution and 1.6 mJy beam -1 sensitivity. New Galactic center nonthermal filaments, new pulsar candidates, and the lowest frequency detection to date of the radio source associated with our Galaxy's central massive black hole result. At 74 MHz I image a region of the sky roughly 40° x 6° with, ~10 feet resolution. I use the high opacity of H II regions at 74 MHz to extract three-dimensional data on the distribution of Galactic cosmic ray emissivity, a measurement possible only at low radio frequencies.

48 CFR 211.275-1 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Documents 211.275-1 Definitions. Bulk commodities, case, palletized unit load, passive RFID tag, and radio frequency identification are defined in the clause at 252.211-7006, Passive Radio Frequency Identification...

Radio frequency phototube and optical clock: High resolution, high rate and highly stable single photon timing technique

DOE Office of Scientific and Technical Information (OSTI.GOV)

Margaryan, Amur

2011-10-01

A new timing technique for single photons based on the radio frequency phototube and optical clock or femtosecond optical frequency comb generator is proposed. The technique has a 20 ps resolution for single photons, is capable of operating with MHz frequencies and achieving 10 fs instability level.

47 CFR 300.1 - Incorporation by reference of the Manual of Regulations and Procedures for Federal Radio...

Code of Federal Regulations, 2011 CFR

2011-10-01

... authority under 47 U.S.C. 901 et seq. and Executive Order 12046 (March 27, 1978). (b) The federal agencies... Regulations and Procedures for Federal Radio Frequency Management. 300.1 Section 300.1 Telecommunication... AND PROCEDURES FOR FEDERAL RADIO FREQUENCY MANAGEMENT § 300.1 Incorporation by reference of the Manual...

47 CFR 300.1 - Incorporation by reference of the Manual of Regulations and Procedures for Federal Radio...

Code of Federal Regulations, 2010 CFR

2010-10-01

... authority under 47 U.S.C. 901 et seq. and Executive Order 12046 (March 27, 1978). (b) The federal agencies... Regulations and Procedures for Federal Radio Frequency Management. 300.1 Section 300.1 Telecommunication... AND PROCEDURES FOR FEDERAL RADIO FREQUENCY MANAGEMENT § 300.1 Incorporation by reference of the Manual...

47 CFR 300.1 - Incorporation by reference of the Manual of Regulations and Procedures for Federal Radio...

Code of Federal Regulations, 2014 CFR

2014-10-01

... authority under 47 U.S.C. 901 et seq. and Executive Order 12046 (March 27, 1978). (b) The Federal agencies... Regulations and Procedures for Federal Radio Frequency Management. 300.1 Section 300.1 Telecommunication... AND PROCEDURES FOR FEDERAL RADIO FREQUENCY MANAGEMENT § 300.1 Incorporation by reference of the Manual...

47 CFR 300.1 - Incorporation by reference of the Manual of Regulations and Procedures for Federal Radio...

Code of Federal Regulations, 2013 CFR

2013-10-01

... authority under 47 U.S.C. 901 et seq. and Executive Order 12046 (March 27, 1978). (b) The Federal agencies... Regulations and Procedures for Federal Radio Frequency Management. 300.1 Section 300.1 Telecommunication... AND PROCEDURES FOR FEDERAL RADIO FREQUENCY MANAGEMENT § 300.1 Incorporation by reference of the Manual...

47 CFR 300.1 - Incorporation by reference of the Manual of Regulations and Procedures for Federal Radio...

Code of Federal Regulations, 2012 CFR

2012-10-01

... authority under 47 U.S.C. 901 et seq. and Executive Order 12046 (March 27, 1978). (b) The federal agencies... Regulations and Procedures for Federal Radio Frequency Management. 300.1 Section 300.1 Telecommunication... AND PROCEDURES FOR FEDERAL RADIO FREQUENCY MANAGEMENT § 300.1 Incorporation by reference of the Manual...

Radio Frequency (RF) Trap for Confinement of Antimatter Plasmas Using Rotating Wall Electric Fields

NASA Technical Reports Server (NTRS)

Sims, William Herbert, III; Pearson, J. Boise

2004-01-01

Perturbations associated with a rotating wall electric field enable the confinement of ions for periods approaching weeks. This steady state confinement is a result of a radio frequency manipulation of the ions. Using state-of-the-art techniques it is shown that radio frequency energy can produce useable manipulation of the ion cloud (matter or antimatter) for use in containment experiments. The current research focuses on the improvement of confinement systems capable of containing and transporting antimatter.

A Student's Hands-on Introduction to Radio Astronomy With the Simple Construction, Operation and Testing, Utilizing Commonly Available Materials, of a Functioning Solar Radio Telescope

NASA Astrophysics Data System (ADS)

Knight, D.

2016-12-01

Our study of the Sun, an object that provides life to this planet but also is a serious threat to the existence we now enjoy, is frequently limited in hands-on activities by the unavailability of the necessary observational tools. While small optical telescopes are more easily obtained, telescopes that work the other regions of the electromagnetic spectrum, such as the radio frequencies, are unusual. Radio emissions from solar storms, however, can be "viewed" by a student constructing a simple, tunable and inexpensive radio telescope designed to receive the most common radio frequencies broadcast from the Sun during such a storm. The apparatus employs normally available materials and technology in new purposes. Utilizing this telescope, students have the ability to test and modify its design for changes in frequency and signal amplitude, and therefore examine a wide spectrum of radio emission emanating from our star. This engaging introduction to radio electronics not only involves the study of the electrical circuit involved, but also sets the student up for detailed study in the form of specific research projects focusing on solar activity in the radio wavelengths. So far, my students have been actively involved in varying the electrical properties of a simple one-transistor circuit that selects the observational frequencies of the solar radio telescope they have constructed. Student research projects also have examined antenna design in terms of directionality and signal strength gain. In the future, collaboration is possible to link student observers in different locations on this planet, allowing for significant peer evaluation and cooperation. NASA's "Project Jove", a program that Sonoma Valley High School and Robert Ferguson Observatory have been connected with since about the year 2000, already has a worldwide collaboration network in place for similar student-operated radio telescopes for primarily studying Jupiter. Because of the higher frequencies with most of the solar storm radio spectrum, our apparatus is correspondingly much smaller and easier to manipulate, thus promoting student research on a much larger scale.

Air-coupled ultrasound stimulated optical vibrometry for resonance analysis of rubber tubes

PubMed Central

Zhang, Xiaoming; Kinnick, Randall R.; Greenleaf, James F.

2008-01-01

Air-coupled ultrasound stimulated optical vibrometry is proposed to generate and detect the resonances of a rubber tube in air. Amplitude-modulated (AM) focused ultrasound radiation force from a broadband air-coupled ultrasound transducer with center frequency of 500 kHz is used to generate a low frequency vibration in the tube. The resonances of several modes of the tube are measured with a laser vibrometer of 633 nm wavelength. A wave propagation approach is used to calculate the resonances of the tube from its known material properties. Theoretical and experimental resonance frequencies agree within 5%. This method may be useful in measuring the in vitro elastic properties of arteries from the resonance measurements in air. It may also be helpful in better understanding the coupling effects of surrounding tissue and interior blood on the vessel wall by measuring the resonance of the vessel in vitro and in vivo. PMID:18499208

Air-coupled ultrasound stimulated optical vibrometry for resonance analysis of rubber tubes.

PubMed

Zhang, Xiaoming; Kinnick, Randall R; Greenleaf, James F

2009-01-01

Air-coupled ultrasound stimulated optical vibrometry is proposed to generate and detect the resonances of a rubber tube in air. Amplitude-modulated (AM) focused ultrasound radiation force from a broadband air-coupled ultrasound transducer with center frequency of 500 kHz is used to generate a low frequency vibration in the tube. The resonances of several modes of the tube are measured with a laser vibrometer of 633 nm wavelength. A wave propagation approach is used to calculate the resonances of the tube from its known material properties. Theoretical and experimental resonance frequencies agree within 5%. This method may be useful in measuring the in vitro elastic properties of arteries from the resonance measurements in air. It may also be helpful to better understand the coupling effects of the surrounding tissue and interior blood on the vessel wall by measuring the resonance of the vessel in vitro and in vivo.

Broadband Vibration Detection in Tissue Phantoms Using a Fiber Fabry-Perot Cavity.

PubMed

Barnes, Jack; Li, Sijia; Goyal, Apoorv; Abolmaesumi, Purang; Mousavi, Parvin; Loock, Hans-Peter

2018-04-01

A fiber optic vibration sensor is developed and characterized with an ultrawide dynamic sensing range, from less than 1 Hz to clinical ultrasound frequencies near 6 MHz. The vibration sensor consists of a matched pair of fiber Bragg gratings coupled to a custom-built signal processing circuit. The wavelength of a laser diode is locked to one of the many cavity resonances using the Pound-Drever-Hall scheme. A calibrated piezoelectric vibration element was used to characterize the sensor's strain, temperature, and noise responses. To demonstrate its sensing capability, an ultrasound phantom with built-in low frequency vibration actuation was constructed. The fiber optic senor was shown to simultaneously capture the low frequency vibration and the clinical ultrasound transmission waveforms with nanostrain sensitivity. This miniaturized and sensitive vibration sensor can provide comprehensive information regarding strain response and the resultant ultrasound waveforms.

Time-resolved fluorescence observation of di-tyrosine formation in horseradish peroxidase upon ultrasound treatment leading to enzyme inactivation

NASA Astrophysics Data System (ADS)

Tsikrika, Konstantina; Lemos, M. Adília; Chu, Boon-Seang; Bremner, David H.; Hungerford, Graham

2017-02-01

The application of ultrasound to a solution can induce cavitional phenomena and generate high localised temperatures and pressures. These are dependent of the frequency used and have enabled ultrasound application in areas such as synthetic, green and food chemistry. High frequency (100 kHz to 1 MHz) in particular is promising in food chemistry as a means to inactivate enzymes, replacing the need to use periods of high temperature. A plant enzyme, horseradish peroxidase, was studied using time-resolved fluorescence techniques as a means to assess the effect of high frequency (378 kHz and 583 kHz) ultrasound treatment at equivalent acoustic powers. This uncovered the fluorescence emission from a newly formed species, attributed to the formation of di-tyrosine within the horseradish peroxidase structure caused by auto-oxidation, and linked to enzyme inactivation.

Radio-Frequency-Controlled Cold Collisions and Universal Properties of Unitary Bose Gases

NASA Astrophysics Data System (ADS)

Ding, Yijue

This thesis investigates two topics: ultracold atomic collisions in a radio-frequency field and universal properties of a degenerate unitary Bose gas. One interesting point of the unitary Bose gas is that the system has only one length scale, that is, the average interparticle distance. This single parameter determines all properties of the gas, which is called the universality of the system. We first introduce a renormalized contact interaction to extend the validity of the zero-range interaction to large scattering lengths. Then this renormalized interaction is applied to many-body theories to determined those universal relations of the system. From the few-body perspective, we discuss the scattering between atoms in a single-color radio-frequency field. Our motivation is proposing the radio-frequency field as an effective tool to control interactions between cold atoms. Such a technique may be useful in future experiments such as creating phase transitions in spinor condensates. We also discuss the formation of ultracold molecules using radio-freqency fields from a time-dependent approach.

47 CFR 97.307 - Emission standards.

Code of Federal Regulations, 2013 CFR

2013-10-01

...-modulated emission may have a modulation index greater than 1 at the highest modulation frequency. (2) No..., or for frequency-shift keying, the frequency shift between mark and space must not exceed 1 kHz. (5... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AMATEUR RADIO...

47 CFR 97.307 - Emission standards.

Code of Federal Regulations, 2011 CFR

2011-10-01

...-modulated emission may have a modulation index greater than 1 at the highest modulation frequency. (2) No..., or for frequency-shift keying, the frequency shift between mark and space must not exceed 1 kHz. (5... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AMATEUR RADIO...

47 CFR 97.307 - Emission standards.

Code of Federal Regulations, 2012 CFR

2012-10-01

...-modulated emission may have a modulation index greater than 1 at the highest modulation frequency. (2) No..., or for frequency-shift keying, the frequency shift between mark and space must not exceed 1 kHz. (5... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AMATEUR RADIO...

47 CFR 97.307 - Emission standards.

Code of Federal Regulations, 2014 CFR

2014-10-01

...-modulated emission may have a modulation index greater than 1 at the highest modulation frequency. (2) No..., or for frequency-shift keying, the frequency shift between mark and space must not exceed 1 kHz. (5... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AMATEUR RADIO...

47 CFR 97.307 - Emission standards.

Code of Federal Regulations, 2010 CFR

2010-10-01

...-modulated emission may have a modulation index greater than 1 at the highest modulation frequency. (2) No..., or for frequency-shift keying, the frequency shift between mark and space must not exceed 1 kHz. (5... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AMATEUR RADIO...

Tissue identification by ultrasound

NASA Technical Reports Server (NTRS)

Lecroissette, D. H.; Heyser, R. C.; Gammell, P. M.; Wilson, R. L.

1978-01-01

The ultrasonic properties of animal and human soft tissue were measured over the frequency range of 1.5 to 10.0 MHz. The method employed a swept-frequency, coherent technique known as time delay spectrometry. Measurements of attenuation versus frequency on liver, backfat, kidney, pancreas, spleen, breast, and other tissue were made. Considerable attention was paid to tissue handling and in determining the effects of fixing on the attenuation of ultrasound in the tissue.

Comparing Zero Ischemia Laparoscopic Radio Frequency Ablation Assisted Tumor Enucleation and Laparoscopic Partial Nephrectomy for Clinical T1a Renal Tumor: A Randomized Clinical Trial.

PubMed

Huang, Jiwei; Zhang, Jin; Wang, Yanqing; Kong, Wen; Xue, Wei; Liu, Dongming; Chen, YongHui; Huang, Yiran

2016-06-01

We evaluated the functional outcome, safety and efficacy of zero ischemia laparoscopic radio frequency ablation assisted tumor enucleation compared with conventional laparoscopic partial nephrectomy. A prospective randomized controlled trial was conducted from April 2013 to March 2015 in patients with cT1a renal tumor scheduled for laparoscopic nephron sparing surgery. All patients were followed for at least 12 months. Patients in the laparoscopic radio frequency ablation assisted tumor enucleation group underwent tumor enucleation after radio frequency ablation without hilar clamping. The primary outcome was the change in glomerular filtration rate of the affected kidney by renal scintigraphy at 12 months. Secondary outcomes included changes in estimated glomerular filtration rate, estimated blood loss, operative time, hospital stay, postoperative complications and oncologic outcomes. The Pearson chi-square or Fisher exact, Student t-test and Wilcoxon rank sum tests were used. The trial ultimately enrolled 89 patients, of whom 44 were randomized to the laparoscopic radio frequency ablation assisted tumor enucleation group and 45 to the laparoscopic partial nephrectomy group. In the laparoscopic partial nephrectomy group 1 case was converted to radical nephrectomy. Compared with the laparoscopic partial nephrectomy group, patients in the laparoscopic radio frequency ablation assisted tumor enucleation group had a smaller decrease in glomerular filtration rate of the affected kidney at 3 months (10.2% vs 20.5%, p=0.001) and 12 months (7.6% vs 16.2%, p=0.002). Patients in the laparoscopic radio frequency ablation assisted tumor enucleation group had a shorter operative time (p=0.002), lower estimated blood loss (p <0.001) and a shorter hospital stay (p=0.029) but similar postoperative complications (p=1.000). There were no positive margins or local recurrence in this study. Zero ischemia laparoscopic radio frequency ablation assisted tumor enucleation enables tumor excision with better renal function preservation compared to conventional laparoscopic partial nephrectomy. Less blood loss and a shorter operative time were achieved with similar postoperative complication rates. Copyright © 2016 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Photoacoustic image reconstruction from ultrasound post-beamformed B-mode image

NASA Astrophysics Data System (ADS)

Zhang, Haichong K.; Guo, Xiaoyu; Kang, Hyun Jae; Boctor, Emad M.

2016-03-01

A requirement to reconstruct photoacoustic (PA) image is to have a synchronized channel data acquisition with laser firing. Unfortunately, most clinical ultrasound (US) systems don't offer an interface to obtain synchronized channel data. To broaden the impact of clinical PA imaging, we propose a PA image reconstruction algorithm utilizing US B-mode image, which is readily available from clinical scanners. US B-mode image involves a series of signal processing including beamforming, followed by envelope detection, and end with log compression. Yet, it will be defocused when PA signals are input due to incorrect delay function. Our approach is to reverse the order of image processing steps and recover the original US post-beamformed radio-frequency (RF) data, in which a synthetic aperture based PA rebeamforming algorithm can be further applied. Taking B-mode image as the input, we firstly recovered US postbeamformed RF data by applying log decompression and convoluting an acoustic impulse response to combine carrier frequency information. Then, the US post-beamformed RF data is utilized as pre-beamformed RF data for the adaptive PA beamforming algorithm, and the new delay function is applied by taking into account that the focus depth in US beamforming is at the half depth of the PA case. The feasibility of the proposed method was validated through simulation, and was experimentally demonstrated using an acoustic point source. The point source was successfully beamformed from a US B-mode image, and the full with at the half maximum of the point improved 3.97 times. Comparing this result to the ground-truth reconstruction using channel data, the FWHM was slightly degraded with 1.28 times caused by information loss during envelope detection and convolution of the RF information.

Bipolar-power-transistor-based limiter for high frequency ultrasound imaging systems.

PubMed

Choi, Hojong; Yang, Hao-Chung; Shung, K Kirk

2014-03-01

High performance limiters are described in this paper for applications in high frequency ultrasound imaging systems. Limiters protect the ultrasound receiver from the high voltage (HV) spikes produced by the transmitter. We present a new bipolar power transistor (BPT) configuration and compare its design and performance to a diode limiter used in traditional ultrasound research and one commercially available limiter. Limiter performance depends greatly on the insertion loss (IL), total harmonic distortion (THD) and response time (RT), each of which will be evaluated in all the limiters. The results indicated that, compared with commercial limiter, BPT-based limiter had less IL (-7.7 dB), THD (-74.6 dB) and lower RT (43 ns) at 100 MHz. To evaluate the capability of these limiters, they were connected to a 100 MHz single element transducer and a two-way pulse-echo test was performed. It was found that the -6 dB bandwidth and sensitivity of the transducer using BPT-based limiter were better than those of the commercial limiter by 22% and 140%, respectively. Compared to the commercial limiter, BPT-based limiter is shown to be capable of minimizing signal attenuation, RT and THD at high frequencies and is thus suited for high frequency ultrasound applications. Copyright © 2013 Elsevier B.V. All rights reserved.

Analysis and measurement of the modulation transfer function of harmonic shear wave induced phase encoding imaging.

PubMed

McAleavey, Stephen A

2014-05-01

Shear wave induced phase encoding (SWIPE) imaging generates ultrasound backscatter images of tissue-like elastic materials by using traveling shear waves to encode the lateral position of the scatters in the phase of the received echo. In contrast to conventional ultrasound B-scan imaging, SWIPE offers the potential advantages of image formation without beam focusing or steering from a single transducer element, lateral resolution independent of aperture size, and the potential to achieve relatively high lateral resolution with low frequency ultrasound. Here a Fourier series description of the phase modulated echo signal is developed, demonstrating that echo harmonics at multiples of the shear wave frequency reveal target k-space data at identical multiples of the shear wavenumber. Modulation transfer functions of SWIPE imaging systems are calculated for maximum shear wave acceleration and maximum shear constraints, and compared with a conventionally focused aperture. The relative signal-to-noise ratio of the SWIPE method versus a conventionally focused aperture is found through these calculations. Reconstructions of wire targets in a gelatin phantom using 1 and 3.5 MHz ultrasound and a cylindrical shear wave source are presented, generated from the fundamental and second harmonic of the shear wave modulation frequency, demonstrating weak dependence of lateral resolution with ultrasound frequency.

Dynamic Observation of the Morphological Changes in Paraurethral Ducts Infected with Gonococci in Men before and after Ceftriaxone Therapy Using High-Frequency Ultrasound.

PubMed

Fan, Wenge; Zhang, Qingsong; Ye, Xun; Fan, Zhijiang

2018-01-01

To observe the morphological changes in paraurethral ducts infected with gonococci in men before and after the administration of the ceftriaxone therapy using high-frequency ultrasound and determine its clinical significance. Thirty-two male patients with gonococcal paraurethral duct infection were enrolled. Their lesions were examined using an ACUSON X300 ultrasound system before and after they were subjected to ceftriaxone therapy. The paraurethral duct was completely closed 3-4 days after ceftriaxone treatment in 30 patients. Paraurethral duct closure began from the blind end and proceeded gradually towards its orifice; during closure, the paraurethral duct diameter showed no apparent change. These 30 patients whose paraurethral ducts closed were considered cured. In the remaining 2 patients, the length and diameter of the paraurethral ducts showed no change before and after ceftriaxone treatment; one patient was unresponsive to ceftriaxone treatment, and the other had secondary dilatation of the paraurethral duct. These 2 patients were cured after surgery. High-frequency ultrasound enables dynamic observation of the morphological changes in paraurethral ducts infected with gonococci before and after ceftriaxone therapy. High-frequency ultrasound can provide valuable information for incision, drainage, and wedge resection of paraurethral ducts. © 2017 S. Karger AG, Basel.

Clusters of Galaxies and the Cosmic Web with Square Kilometre Array

NASA Astrophysics Data System (ADS)

Kale, Ruta; Dwarakanath, K. S.; Vir Lal, Dharam; Bagchi, Joydeep; Paul, Surajit; Malu, Siddharth; Datta, Abhirup; Parekh, Viral; Sharma, Prateek; Pandey-Pommier, Mamta

2016-12-01

The intra-cluster and inter-galactic media that pervade the large scale structure of the Universe are known to be magnetized at sub-micro Gauss to micro Gauss levels and to contain cosmic rays. The acceleration of cosmic rays and their evolution along with that of magnetic fields in these media is still not well understood. Diffuse radio sources of synchrotron origin associated with the Intra-Cluster Medium (ICM) such as radio halos, relics and mini-halos are direct probes of the underlying mechanisms of cosmic ray acceleration. Observations with radio telescopes such as the Giant Metrewave Radio Telescope, the Very Large Array and the Westerbork Synthesis Radio Telescope have led to the discoveries of about 80 such sources and allowed detailed studies in the frequency range 0.15-1.4 GHz of a few. These studies have revealed scaling relations between the thermal and non-thermal properties of clusters and favour the role of shocks in the formation of radio relics and of turbulent re-acceleration in the formation of radio halos and mini-halos. The radio halos are known to occur in merging clusters and mini-halos are detected in about half of the cool-core clusters. Due to the limitations of current radio telescopes, low mass galaxy clusters and galaxy groups remain unexplored as they are expected to contain much weaker radio sources. Distinguishing between the primary and the secondary models of cosmic ray acceleration mechanisms requires spectral measurements over a wide range of radio frequencies and with high sensitivity. Simulations have also predicted weak diffuse radio sources associated with filaments connecting galaxy clusters. The Square Kilometre Array (SKA) is a next generation radio telescope that will operate in the frequency range of 0.05-20 GHz with unprecedented sensitivities and resolutions. The expected detection limits of SKA will reveal a few hundred to thousand new radio halos, relics and mini-halos providing the first large and comprehensive samples for their study. The wide frequency coverage along with sensitivity to extended structures will be able to constrain the cosmic ray acceleration mechanisms. The higher frequency (>5 GHz) observations will be able to use the Sunyaev-Zel'dovich effect to probe the ICM pressure in addition to tracers such as lobes of head-tail radio sources. The SKA also opens prospects to detect the `off-state' or the lowest level of radio emission from the ICM predicted by the hadronic models and the turbulent re-acceleration models.

High-frequency ultrasound evaluation of cellulite treated with the 1064 nm Nd:YAG laser.

PubMed

Bousquet-Rouaud, Regine; Bazan, Marie; Chaintreuil, Jean; Echague, Agustina Vila

2009-03-01

To investigate non-invasive laser treatment for cellulite using the 1064 nm Nd:YAG laser and to correlate clinical results with high-frequency skin ultrasound images. Twelve individuals of normal weight were treated on either the left or right posterior side of the thigh with the following parameters: fluence 30 J/cm, 18 mm spot size and dynamic cooling device pulse duration of 30 ms. Three treatments were performed at intervals of 3-4 weeks, and followed-up 1 and 3 months after the last session. Photographs and ultrasound imaging were assessed before each session. The 1064 nm Nd:YAG laser resulted in a tightening of the skin and an improvement in cellulite. No side effects were reported. High-resolution ultrasound imaging showed a significant improvement in dermis density and a reduction of dermis thickness. The method is described in detail in Appendix 1. Infra-red lasers may constitute a safe and effective treatment for cellulite and high-frequency ultrasound imaging provides a quantitative and objective measurement of the treatment efficacy.

The effects of temperature and frequencies in ultrasound assisted extraction of phycocyanin from microalgae Spirulina sp

NASA Astrophysics Data System (ADS)

Hadiyanto, Suttrisnorhadi, Sutanto, Heri; Suzery, Meiny; Soetrisnanto, Danny; Azizah, Nur

2015-12-01

Microalgae Spirulina sp has been identified as source of protein and other high added value compounds. One of the compounds is phycocyanin as also known for antioxidant use. The extraction of this compound by using conventional method (soxhlet extraction) resulted low yield and longer processing time. This research was aimed to extract phycocyanin by using an extraction assisted by ultrasound irradiation. The extraction was performed by using variable of ultrasound frequency and extraction temperature and ethanol was used as a solvent. The result showed that yield of phycocyanin extracted by conventional method was 11.13% while the ultrasound irradiation could increase the yield up to 15.61% at constant frequency of 42 kHz, while the optimum temperature was obtained at 45°C. The analysis of variable interactions showed that both temperature and time has an interaction and temperature was the highest variable in increasing the yield. The conclusion of this research was the ultrasound could improve significantly the efficiency of extraction as well as activity of phycocyanin extracted from microalgae.

The effects of temperature and frequencies in ultrasound assisted extraction of phycocyanin from microalgae Spirulina sp

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hadiyanto,, E-mail: hadiyanto@live.undip.ac.id; Suttrisnorhadi,; Soetrisnanto, Danny

Microalgae Spirulina sp has been identified as source of protein and other high added value compounds. One of the compounds is phycocyanin as also known for antioxidant use. The extraction of this compound by using conventional method (soxhlet extraction) resulted low yield and longer processing time. This research was aimed to extract phycocyanin by using an extraction assisted by ultrasound irradiation. The extraction was performed by using variable of ultrasound frequency and extraction temperature and ethanol was used as a solvent. The result showed that yield of phycocyanin extracted by conventional method was 11.13% while the ultrasound irradiation could increasemore » the yield up to 15.61% at constant frequency of 42 kHz, while the optimum temperature was obtained at 45°C. The analysis of variable interactions showed that both temperature and time has an interaction and temperature was the highest variable in increasing the yield. The conclusion of this research was the ultrasound could improve significantly the efficiency of extraction as well as activity of phycocyanin extracted from microalgae.« less

A comparative sonochemical reaction that is independent of the intensity of ultrasound and the geometry of the exposure apparatus.

PubMed

Sostaric, Joe Z

2008-09-01

Sonolysis of aqueous solutions of n-alkyl anionic surfactants results in the formation of secondary carbon-centered radicals (-*CH-). The yield of -*CH- depends on the bulk surfactant concentration up to a maximum attainable radical yield (the 'plateau yield') where an increasing surfactant concentration (below the critical micelle concentration) no longer affects the -*CH- yield. In an earlier study it was found that the ratio of -*CH- detected following sonolysis of aqueous solutions of sodium pentane sulfonate (SPSo) to that of sodium dodecyl sulfate (SDS) (i.e. CH(SPSo)/CH(SDS)) depended on the frequency of sonolysis, but was independent of the ultrasound intensity, at the plateau concentrations [J.Z. Sostaric, P. Riesz, Adsorption of surfactants at the gas/solution interface of cavitation bubbles: an ultrasound intensity-independent frequency effect in sonochemistry, J. Phys. Chem. B 106 (2002) 12537-12548]. In the current study, it was found that the CH(SPSo)/CH(SDS) ratio depended only on the ultrasound frequency and did not depend on the geometry of the ultrasound exposure apparatus considered.

The Telecommunications and Data Acquisition Report

NASA Technical Reports Server (NTRS)

Posner, E. C. (Editor)

1984-01-01

Developments in space communications, radio navigation, radio science, ground-base radio astronomy, reports on the Deep Space Network (DSN) and its Ground Communications Facility (GCF), and applications of radio interferometry at microwave frequencies are discussed.

High-resolution ultrasonic imaging of the posterior segment.

PubMed

Coleman, D Jackson; Silverman, Ronald H; Chabi, Almira; Rondeau, Mark J; Shung, K Kirk; Cannata, Jon; Lincoff, Harvey

2004-07-01

Conventional ophthalmic ultrasonography is performed using 10-megahertz (MHz) transducers. Our aim was to explore the use of higher frequency ultrasound to provide improved resolution of the posterior pole. Prospective case series. One normal subject and 5 subjects with pathologies affecting the posterior coats, including nevii, small melanomas, and macular hole. We modeled the frequency-dependent attenuation of ultrasound across the eye to develop an understanding of the range of frequencies that might be practically applied for imaging of the posterior pole. We compared images of the posterior coats made at 10, 15, and 20 MHz, and 20-MHz ultrasound images of pathologies with 10-MHz ultrasound and optical coherence tomography (OCT). Ability to resolve normal and pathologic structures affecting posterior coats of the eye. Modeling showed that frequencies of 20 to 25 MHz might be used for posterior pole imaging. Twenty-megahertz images allowed differentiation of the retina, choroid, and sclera. In addition, at 20 MHz the retina showed banding patterns suggesting an internal structure comparable in many respects to that seen in OCT and histology. Images of ocular pathology provided much improved detail relative to 10-MHz images and deeper penetration than OCT. Twenty-megahertz ultrasound can be practically employed for imaging of the posterior pole of the eye, providing a 2-fold improvement in resolution relative to conventional 10-MHz instruments. Although not providing the resolution of OCT, ultrasound can be used in the presence of optical opacities and allows evaluation of deeper tissue structures.

77 FR 53159 - Passenger Use of Portable Electronic Devices on Board Aircraft

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-31

... to navigation systems such as very high frequency (VHF) Omni Range (VOR) navigation systems. \\1\\ 14... navigation, communication, and surveillance radio receivers that may be susceptible at certain frequencies to... space by electromagnetic waves on specific radio frequencies that are used to communicate information...

Ultra-wideband technology radio frequency interference effects to GPS and interference scenario development : first interim report

DOT National Transportation Integrated Search

2000-09-12

In October, 1999, at the request of the Department of Transportation (DoT), the RTCA undertook an effort to investigate the radio frequency interference (RFI) environment in the vicinity of the new Global Positioning System (GPS) L5 frequency (1176.4...

Measuring changes of radio-frequency dielectric properties of chicken meat during storage

USDA-ARS?s Scientific Manuscript database

Changes in dielectric properties of stored chicken meat were tracked by using a radio-frequency dielectric spectroscopy method. For this purpose, the dielectric properties were measured with an open-ended coaxial-line probe and vector network analyzer over a broad frequency range from 200 MHz to 20...

Prediction of scour depth in gravel bed rivers using radio frequency IDs : application to the Skagit River.

DOT National Transportation Integrated Search

2013-10-01

The overarching goal of the proposed research was to develop, test and verify a robust system based on the Low Frequency (134.2 : kHz), passive Radio Frequency Identification (RFID) technology to be ultimately used for determining the maximum scour d...

An assessment of the impact of radio frequency interference on microwave SETI searches

NASA Technical Reports Server (NTRS)

Klein, M. J.; Gulkis, S.; Olsen, E. T.; Armstrong, E. F.; Jackson, E. B.

1987-01-01

The problem posed for SETI by radio frequency interference (RFI) is briefly discussed. The degree to which various frequencies are subject to RFI is indicated, and predictions about the future of such interference are made. Suggestions for coping with the problem are given.

RFID Transponders' Radio Frequency Emissions in Aircraft Communication and Navigation Radio Bands

NASA Technical Reports Server (NTRS)

Nguyen, Truong X.; Ely, Jay J.; Williams, Reuben A.; Koppen, Sandra V.; Salud, Maria Theresa P.

2006-01-01

Radiated emissions in aircraft communication and navigation bands are measured from several active radio frequency identification (RFID) tags. The individual tags are different in design and operations. They may also operate in different frequency bands. The process for measuring the emissions is discussed, and includes tag interrogation, reverberation chamber testing, and instrument settings selection. The measurement results are described and compared against aircraft emission limits. In addition, interference path loss for the cargo bays of passenger aircraft is measured. Cargo bay path loss is more appropriate for RFID tags than passenger cabin path loss. The path loss data are reported for several aircraft radio systems on a Boeing 747 and an Airbus A320.

Ultrasound pressure distributions generated by high frequency transducers in large reactors.

PubMed

Leong, Thomas; Coventry, Michael; Swiergon, Piotr; Knoerzer, Kai; Juliano, Pablo

2015-11-01

The performance of an ultrasound reactor chamber relies on the sound pressure level achieved throughout the system. The active volume of a high frequency ultrasound chamber can be determined by the sound pressure penetration and distribution provided by the transducers. This work evaluated the sound pressure levels and uniformity achieved in water by selected commercial scale high frequency plate transducers without and with reflector plates. Sound pressure produced by ultrasonic plate transducers vertically operating at frequencies of 400 kHz (120 W) and 2 MHz (128 W) was characterized with hydrophones in a 2 m long chamber and their effective operating distance across the chamber's vertical cross section was determined. The 2 MHz transducer produced the highest pressure amplitude near the transducer surface, with a sharp decline of approximately 40% of the sound pressure occurring in the range between 55 and 155 mm from the transducer. The placement of a reflector plate 500 mm from the surface of the transducer was shown to improve the sound pressure uniformity of 2 MHz ultrasound. Ultrasound at 400 kHz was found to penetrate the fluid up to 2 m without significant losses. Furthermore, 400 kHz ultrasound generated a more uniform sound pressure distribution regardless of the presence or absence of a reflector plate. The choice of the transducer distance to the opposite reactor wall therefore depends on the transducer plate frequency selected. Based on pressure measurements in water, large scale 400 kHz reactor designs can consider larger transducer distance to opposite wall and larger active cross-section, and therefore can reach higher volumes than when using 2 MHz transducer plates. Crown Copyright © 2015. Published by Elsevier B.V. All rights reserved.

Inexpensive Ultrasound Demonstrations as Analogs of Radio Diffraction in the field : Huygens Probe Bistatic experiment on Titan and the Sea Interferometer (Invited)

NASA Astrophysics Data System (ADS)

Lorenz, R. D.

2013-12-01

The wave nature of electromagnetic radiation can be exploited in a number of astronomical and remote sensing methods, but is often challenging to visualize in the classroom. One approach with conveniently-inexpensive components is to use sound as an analog. Readily-available ultrasonic transducers at 40 kHz can be driven with a 555 oscillator and received intensity detected with an op-amp and visualized with a digital voltmeter, a lightbulb, or even acoustically. The wavelength of 9mm is convenient for tabletop experiments, with a relevant example being Lloyds Mirror, the interference of a direct wave from a source just above a surface with the reflected wave. As a distant receiver moves in angle through this interference pattern, a series of peaks and nulls in recorded intensity can be interpreted as the height of the transmitter and the reflectivity (i.e. with some assumptions, the roughness) of the reflecting surface. This $10 experiment will be demonstrated at the poster. Such an observation was (serendipitously) made in 2005 after the landing of the Huygens probe on the surface of Titan, where the radio signal measured by Cassini as it set on the horizon as seen from the probe underwent sharp dips in strength that were inverted into a precise measurement of the post-impact probe height. A similar technique in reverse was applied a half century earlier in early Australian radio astronomy to measure the position and width of astrophysical sources from a single clifftop antenna. Ultrasound can be convenient to emulate other radio work, exploiting Doppler effects and (for pulsed sources, like those used in rangers for amateur robotics) propagation time rather than diffraction. Some experiments on tracking Frisbees as an analog for measuring planetary winds by tracking descent probes, and on bistatic delay/Doppler scatterometry as in the CYGNSS GPS-based experiment to measure hurricane winds via sea state, will also be discussed. Huygens probe on the surface of Titan. The interference pattern constrained Titan surface properties Ultrasound pattern is a function of geometry and surface covering

Review of Radio Frequency Photonics Basics

DTIC Science & Technology

2017-09-06

essentially from “Direct Current to Daylight,” allowing use for high frequency applications. This report covers some needs and advantages of radio...operate essentially from “Direct Current (DC) to Daylight,” allowing use for high frequency applications. The following sections of this report cover...spectrum leaving higher frequencies open for new uses. Frequency bands from 600 MHz to 5 GHz are used for commercial communications in the US. The future

Tactical Radios: Multiservice Communications Procedures for Tactical Radios in a Joint Environment

DTIC Science & Technology

2002-06-01

joint restricted frequency list (JRFL). It specifies the frequency allocations for communication and jamming missions restricted from use by...coordination commit- tee also builds the frequency list for the mission sets. In building the list, the committee should use JACS or RBECS software...restricted frequency list . A time and geographical listing of prioritized frequencies essential to an operation and restricted from targeting by friendly EP

Radio Frequency Identification Applications in Pavements

DOT National Transportation Integrated Search

2014-08-01

Radio frequency identification (RFID) technology is widely used for inventory control, tool and material tracking, and other similar applications where line-of-sight optical bar codes are inconvenient or impractical. Several applications of RFID tech...

Non-exponential decoherence of radio-frequency resonance rotation of spin in storage rings

NASA Astrophysics Data System (ADS)

Saleev, A.; Nikolaev, N. N.; Rathmann, F.; Hinder, F.; Pretz, J.; Rosenthal, M.

2017-08-01

Precision experiments, such as the search for electric dipole moments of charged particles using radio-frequency spin rotators in storage rings, demand for maintaining the exact spin resonance condition for several thousand seconds. Synchrotron oscillations in the stored beam modulate the spin tune of off-central particles, moving it off the perfect resonance condition set for central particles on the reference orbit. Here, we report an analytic description of how synchrotron oscillations lead to non-exponential decoherence of the radio-frequency resonance driven up-down spin rotations. This non-exponential decoherence is shown to be accompanied by a nontrivial walk of the spin phase. We also comment on sensitivity of the decoherence rate to the harmonics of the radio-frequency spin rotator and a possibility to check predictions of decoherence-free magic energies.

Pulsar current sheet C̆erenkov radiation

NASA Astrophysics Data System (ADS)

Zhang, Fan

2018-04-01

Plasma-filled pulsar magnetospheres contain thin current sheets wherein the charged particles are accelerated by magnetic reconnections to travel at ultra-relativistic speeds. On the other hand, the plasma frequency of the more regular force-free regions of the magnetosphere rests almost precisely on the upper limit of radio frequencies, with the cyclotron frequency being far higher due to the strong magnetic field. This combination produces a peculiar situation, whereby radio-frequency waves can travel at subluminal speeds without becoming evanescent. The conditions are thus conducive to C̆erenkov radiation originating from current sheets, which could plausibly serve as a coherent radio emission mechanism. In this paper we aim to provide a portrait of the relevant processes involved, and show that this mechanism can possibly account for some of the most salient features of the observed radio signals.

Interplanetary radio storms. 2: Emission levels and solar wind speed in the range 0.05-0.8 AU

NASA Technical Reports Server (NTRS)

Bougeret, J. L.; Fainberg, J.; Stone, R. G.

1982-01-01

Storms of interplanetary type III radio bursts (IP storms) are commonly observed in the interplanetry medium by the ISEE-3 radio instrument. This instrument has the capability of accurately determining the arrival direction of the radio emission. At each observing frequency, the storm radio sources are tracked as they cross the line-of-sight to the Sun. Usng a simple model, the emission levels are determined at a number of radio frequencies for four separate storms. The IP storm radiation is found to occur in regions of enhanced density at levels of 0.05 to 0.8 AU. The density in these enhancements falls off faster than R(-2). The solar wind speed in the storm region is also measured. The analysis is consistent with steady conditions in the storm region during a few days around the central meridian passage of the storm. The comparison with average in situ density measurements compiled from the HELIOS 1-2 observations favors type III storm burst radio emission at the harmonic of the local plasma frequency.

Time and Frequency Synchronization on the Virac Radio Telescope RT-32

NASA Astrophysics Data System (ADS)

Bezrukovs, V.

2016-04-01

One of the main research directions of Ventspils International Radio Astronomy Centre (VIRAC) is radio astronomy and astrophysics. The instrumental base for the centre comprised two fully steerable parabolic antennas, RT-16 and RT-32 (i.e. with the mirror diameter of 16 m and 32 m). After long reconstruction, radio telescope RT-32 is currently equipped with the receiving and data acquisition systems that allow observing in a wide frequency range from 327 MHz to 9 GHz. New Antenna Control Unit (ACU) allows stable, fast and precise pointing of antenna. Time and frequency distribution service provide 5, 10 and 100 MHz reference frequency, 1PPS signals and precise time stamps by NTP protocol and in the IRIG-B format by coaxial cable. For the radio astronomical observations, main requirement of spatially Very Long Base Line Interferometric (VLBI) observations for the observatory is precise synchronization of the received and sampled data and linking to the exact time stamps. During October 2015, radio telescope RT-32 performance was tested in several successful VLBI experiments. The obtained results confirm the efficiency of the chosen methods of synchronization and the ability to reproduce them on similar antennas.

A miniature disposable radio (MiDR) for unattended ground sensor systems (UGSS) and munitions

NASA Astrophysics Data System (ADS)

Wells, Jeffrey S.; Wurth, Timothy J.

2004-09-01

Unattended and tactical sensors are used by the U.S. Army"s Future Combat Systems (FCS) and Objective Force Warrior (OFW) to detect and identify enemy targets on the battlefield. The radios being developed as part of the Networked Sensors for the Objective Force (NSOF) are too costly and too large to deploy in missions requiring throw-away hardware. A low-cost miniature radio is required to satisfy the communication needs for unmanned sensor and munitions systems that are deployed in a disposable manner. A low cost miniature disposable communications suite is leveraged using the commercial off-the-shelf market and employing a miniature universal frequency conversion architecture. Employing the technology of universal frequency architecture in a commercially available communication unit delivers a robust disposable transceiver that can operate at virtually any frequency. A low-cost RF communication radio has applicability in the commercial, homeland defense, military, and other government markets. Specific uses include perimeter monitoring, infrastructure defense, unattended ground sensors, tactical sensors, and border patrol. This paper describes a low-cost radio architecture to meet the requirements of throw-away radios that can be easily modified or tuned to virtually any operating frequency required for the specific mission.

Simultaneous ultrasound and photoacoustics based flow cytometry

NASA Astrophysics Data System (ADS)

Gnyawali, Vaskar; Strohm, Eric M.; Tsai, Scott S. H.; Kolios, Michael C.

2018-04-01

We have developed a flow cytometer based on simultaneous detection of ultrasound and photoacoustic waves from individual particles/cells flowing in a microfluidic channel. Our polydimethylsiloxane (PDMS) based hydrodynamic 3-dimensional (3D) flow-focusing microfluidic device contains a cross-junction channel, a micro-needle (ID 100 μm and OD 200 μm) insert, and a 3D printed frame to hold and align a high frequency (center frequency 375 MHz) ultrasound transducer. The focused flow passes through a narrow focal zone with lateral and axial focal lengths of 6-8 μm and 15-20 μm, respectively. Both the lateral and axial alignments are achieved by screwing the transducer to the frame onto the PDMS device. Individual particles pass through an interrogation zone in the microfluidic channel with a collinearly aligned ultrasound transducer and a focused 532 nm wavelength laser beam. The particles are simultaneously insonified by high-frequency ultrasound and irradiated by a laser beam. The ultrasound backscatter and laser generated photoacoustic waves are detected for each passing particle. The backscattered ultrasound and photoacoustic signal are strongly dependent on the size, morphology, mechanical properties, and material properties of the flowing particles; these parameters can be extracted by analyzing unique features in the power spectrum of the signals. Frequencies less than 100 MHz do not have these unique spectral signatures. We show that we can reliably distinguish between different particles in a sample using the acoustic-based flow cytometer. This technique, when extended to biomedical applications, allows us to rapidly analyze the spectral signatures from individual single cells of a large cell population, with applications towards label-free detection and characterization of healthy and diseased cells.

A simulation model for predicting the temperature during the application of MR-guided focused ultrasound for stroke treatment using pulsed ultrasound

NASA Astrophysics Data System (ADS)

Hadjisavvas, V.; Damianou, C.

2011-09-01

In this paper a simulation model for predicting the temperature during the application of MR-guided focused ultrasound for stroke treatment using pulsed ultrasound is presented. A single element spherically focused transducer of 5 cm diameter, focusing at 10 cm and operating at either 0.5 MHz or 1 MHz was considered. The power field was estimated using the KZK model. The temperature was estimated using the bioheat equation. The goal was to extract the acoustic parameters (power, pulse duration, duty factor and pulse repetition frequency) that maintain a temperature increase of less than 1 °C during the application of a pulse ultrasound protocol. It was found that the temperature change increases linearly with duty factor. The higher the power, the lower the duty factor needed to keep the temperature change to the safe limit of 1 °C. The higher the frequency the lower the duty factor needed to keep the temperature change to the safe limit of 1 °C. Finally, the deeper the target, the higher the duty factor needed to keep the temperature change to the safe limit of 1 °C. The simulation model was tested in brain tissue during the application of pulse ultrasound and the measured temperature was in close agreement with the simulated temperature. This simulation model is considered to be very useful tool for providing acoustic parameters (frequency, power, duty factor, pulse repetition frequency) during the application of pulsed ultrasound at various depths in tissue so that a safe temperature is maintained during the treatment. This model could be tested soon during stroke clinical trials.

High-Frequency Ultrasound M-mode Imaging for Identifying Lesion and Bubble Activity during High-Intensity Focused Ultrasound Ablation

PubMed Central

Kumon, R. E.; Gudur, M. S. R.; Zhou, Y.; Deng, C. X.

2012-01-01

Effective real-time monitoring of high-intensity focused ultrasound (HIFU) ablation is important for application of HIFU technology in interventional electrophysiology. This study investigated rapid, high-frequency M-mode ultrasound imaging for monitoring spatiotemporal changes during HIFU application. HIFU (4.33 MHz, 1 kHz PRF, 50% duty cycle, 1 s, 2600 – 6100 W/cm2) was applied to ex-vivo porcine cardiac tissue specimens with a confocally and perpendicularly aligned high-frequency imaging system (Visualsonics Vevo 770, 55 MHz center frequency). Radiofrequency (RF) data from M-mode imaging (1 kHz PRF, 2 s × 7 mm) was acquired before, during, and after HIFU treatment (n = 12). Among several strategies, the temporal maximum integrated backscatter with a threshold of +12 dB change showed the best results for identifying final lesion width (receiver-operating characteristic curve area 0.91 ± 0.04, accuracy 85 ± 8%, as compared to macroscopic images of lesions). A criterion based on a line-to-line decorrelation coefficient is proposed for identification of transient gas bodies. PMID:22341055

Probing the Jet Turnover Frequency Dependence on Mass and Mass Accretion Rate

NASA Astrophysics Data System (ADS)

Hammerstein, Erica; Gültekin, Kayhan; King, Ashley

2018-01-01

We have examined a sample of 15 sub-Eddington supermassive black holes (SMBHs) in a variety of galaxy classifications to further understand the proposed fundamental plane of black hole activity and scaling relations between black hole masses and their radio and X-ray luminosities. This plane describes black holes from stellar-mass to supermassive. The physics probed by these sub-Eddington systems is thought to be a radiatively inefficient, jet-dominated accretion flow. By studying black holes in this regime, we can learn important information on the disk-jet connection for accreting black holes.A key factor in studying the fundamental plane is the turnover frequency — the frequency at which emission transitions from optically thick at lower frequencies to optically thin at higher frequencies. This turnover point can be measured by observing the source in both radio and X-ray. Our project aims to test the dependence of the turnover frequency on mass and mass accretion rate.Radio observations of the sample were obtained using the Karl G. Jansky Very Large Array (VLA) in the range of 5-40 GHz across four different frequency bands in A configuration to give the highest spatial resolution to focus on the core emission. Our carefully chosen sample of SMBHs with dynamically measured masses consists of two sub-samples: those with approximately constant mass accretion rate (LX/LEdd ~ 10‑7) and those with approximately constant mass (MBH ~ 108 Msun). X-ray data were obtained from archival Chandra observations. To find the turnover frequency, we used Markov Chain Monte Carlo methods to fit two power laws to the radio data and the archival X-ray data. The intersection of the radio and X-ray fits is the turnover frequency.We present the results for both subsamples of SMBHs and their relationship between the turnover frequency and X-ray luminosity, which we take to scale with mass accretion rate, and jet power derived from both radio and X-ray properties.

Investigating the unification of LOFAR-detected powerful AGN in the Boötes field

NASA Astrophysics Data System (ADS)

Morabito, Leah K.; Williams, W. L.; Duncan, Kenneth J.; Röttgering, H. J. A.; Miley, George; Saxena, Aayush; Barthel, Peter; Best, P. N.; Bruggen, M.; Brunetti, G.; Chyży, K. T.; Engels, D.; Hardcastle, M. J.; Harwood, J. J.; Jarvis, Matt J.; Mahony, E. K.; Prandoni, I.; Shimwell, T. W.; Shulevski, A.; Tasse, C.

2017-08-01

Low radio frequency surveys are important for testing unified models of radio-loud quasars and radio galaxies. Intrinsically similar sources that are randomly oriented on the sky will have different projected linear sizes. Measuring the projected linear sizes of these sources provides an indication of their orientation. Steep-spectrum isotropic radio emission allows for orientation-free sample selection at low radio frequencies. We use a new radio survey of the Boötes field at 150 MHz made with the Low-Frequency Array (LOFAR) to select a sample of radio sources. We identify 60 radio sources with powers P > 1025.5 W Hz-1 at 150 MHz using cross-matched multiwavelength information from the AGN and Galaxy Evolution Survey, which provides spectroscopic redshifts and photometric identification of 16 quasars and 44 radio galaxies. When considering the radio spectral slope only, we find that radio sources with steep spectra have projected linear sizes that are on average 4.4 ± 1.4 larger than those with flat spectra. The projected linear sizes of radio galaxies are on average 3.1 ± 1.0 larger than those of quasars (2.0 ± 0.3 after correcting for redshift evolution). Combining these results with three previous surveys, we find that the projected linear sizes of radio galaxies and quasars depend on redshift but not on power. The projected linear size ratio does not correlate with either parameter. The LOFAR data are consistent within the uncertainties with theoretical predictions of the correlation between the quasar fraction and linear size ratio, based on an orientation-based unification scheme.

Satellite observations of type III solar radio bursts at low frequencies

NASA Technical Reports Server (NTRS)

Fainberg, J.; Stone, R. G.

1974-01-01

Type III solar radio bursts have been observed from 10 MHz to 10 kHz by satellite experiments above the terrestrial plasmasphere. Solar radio emission in this frequency range results from excitation of the interplanetary plasma by energetic particles propagating outward along open field lines over distances from 5 earth radii to at least 1 AU from the sun. This review summarizes the morphology, characteristics, and analysis of individual as well as storms of bursts. Substantial evidence is available to show that the radio emission is observed at the second harmonic instead of the fundamental of the plasma frequency. This brings the density scale derived by radio observations into better agreement with direct solar wind density measurements at 1 AU and relaxes the requirement for type III propagation along large density-enhanced regions. This density scale with the measured direction of arrival of the radio burst allows the trajectory of the exciter path to be determined from 10 earth radii to 1 AU.

VLA radio observations of AR Scorpii

NASA Astrophysics Data System (ADS)

Stanway, E. R.; Marsh, T. R.; Chote, P.; Gänsicke, B. T.; Steeghs, D.; Wheatley, P. J.

2018-03-01

Aims: AR Scorpii is unique amongst known white dwarf binaries in showing powerful pulsations extending to radio frequencies. Here we aim to investigate the multi-frequency radio emission of AR Sco in detail, in order to constrain its origin and emission mechanisms. Methods: We present interferometric radio frequency imaging of AR Sco at 1.5, 5 and 9 GHz, analysing the total flux and polarization behaviour of this source at high time resolution (10, 3 and 3 s), across a full 3.6 h orbital period in each band. Results: We find strong modulation of the radio flux on the orbital period and the orbital sideband of the white dwarf's spin period (also known as the "beat" period). This indicates that, like the optical flux, the radio flux arises predominantly from on or near the inner surface of the M-dwarf companion star. The beat-phase pulsations of AR Sco decrease in strength with decreasing frequency. They are strongest at 9 GHz and at an orbital phase 0.5. Unlike the optical emission from this source, radio emission from AR Sco shows weak linear polarization but very strong circular polarization, reaching 30% at an orbital phase 0.8. We infer the probable existence of a non-relativistic cyclotron emission component, which dominates at low radio frequencies. Given the required magnetic fields, this also likely arises from on or near the M-dwarf. A table of the flux time series is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/611/A66

Tunable radio-frequency photonic filter based on an actively mode-locked fiber laser.

PubMed

Ortigosa-Blanch, A; Mora, J; Capmany, J; Ortega, B; Pastor, D

2006-03-15

We propose the use of an actively mode-locked fiber laser as a multitap optical source for a microwave photonic filter. The fiber laser provides multiple optical taps with an optical frequency separation equal to the external driving radio-frequency signal of the laser that governs its repetition rate. All the optical taps show equal polarization and an overall Gaussian apodization, which reduces the sidelobes. We demonstrate continuous tunability of the filter by changing the external driving radio-frequency signal of the laser, which shows good fine tunability in the operating range of the laser from 5 to 10 GHz.

Ultrasound Imaging Using Diffraction Tomography in a Cylindrical Geometry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chambers, D H; Littrup, P

2002-01-24

Tomographic images of tissue phantoms and a sample of breast tissue have been produced from an acoustic synthetic array system for frequencies near 500 kHz. The images for sound speed and attenuation show millimeter resolution and demonstrate the feasibility of obtaining high-resolution tomographic images with frequencies that can deeply penetrate tissue. The image reconstruction method is based on the Born approximation to acoustic scattering and is a simplified version of a method previously used by Andre (Andre, et. al., Int. J. Imaging Systems and Technology, Vol 8, No. 1, 1997) for a circular acoustic array system. The images have comparablemore » resolution to conventional ultrasound images at much higher frequencies (3-5 MHz) but with lower speckle noise. This shows the potential of low frequency, deeply penetrating, ultrasound for high-resolution quantitative imaging.« less

Simulation of laser generated ultrasound with application to defect detection

NASA Astrophysics Data System (ADS)

Pantano, A.; Cerniglia, D.

2008-06-01

Laser generated ultrasound holds substantial promise for use as a tool for defect detection in remote inspection thanks to its ability to produce frequencies in the MHz range, enabling fine spatial resolution of defects. Despite the potential impact of laser generated ultrasound in many areas of science and industry, robust tools for studying the phenomenon are lacking and thus limit the design and optimization of non-destructive testing and evaluation techniques. The laser generated ultrasound propagation in complex structures is an intricate phenomenon and is extremely hard to analyze. Only simple geometries can be studied analytically. Numerical techniques found in the literature have proved to be limited in their applicability, by the frequencies in the MHz range and very short wavelengths. The objective of this research is to prove that by using an explicit integration rule together with diagonal element mass matrices, instead of the almost universally adopted implicit integration rule to integrate the equations of motion in a dynamic analysis, it is possible to efficiently and accurately solve ultrasound wave propagation problems with frequencies in the MHz range travelling in relatively large bodies. Presented results on NDE testing of rails demonstrate that the proposed FE technique can provide a valuable tool for studying the laser generated ultrasound propagation.

Ultrasonic Nakagami-parameter characterization of parotid-gland injury following head-and-neck radiotherapy: A feasibility study of late toxicity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yang, Xiaofeng; Wu, Ning; Wang, Yuefeng

Purpose: The study aims to investigate whether Nakagami parameters—estimated from the statistical distribution of the backscattered ultrasound radio-frequency (RF) signals—could provide a means for quantitative characterization of parotid-gland injury resulting from head-and-neck radiotherapy. Methods: A preliminary clinical study was conducted with 12 postradiotherapy patients and 12 healthy volunteers. Each participant underwent one ultrasound study in which ultrasound scans were performed in the longitudinal, i.e., vertical orientation on the bilateral parotids. For the 12 patients, the mean radiation dose to the parotid glands was 37.7 ± 9.5 Gy, and the mean follow-up time was 16.3 ± 4.8 months. All enrolled patientsmore » experienced grade 1 or 2 late salivary-gland toxicity (RTOG/EORTC morbidity scale). The normal parotid glands served as the control group. The Nakagami-scaling and Nakagami-shape parameters were computed from the RF data to quantify radiation-induced parotid-gland changes. Results: Significant differences in Nakagami parameters were observed between the normal and postradiotherapy parotid glands. Compared with the control group, the Nakagami-scaling parameter of the postradiotherapy group decreased by 25.8% (p < 0.001), and the Nakagami-shape parameter decreased by 31.3% (p < 0.001). The area under the receiver operating characteristic curve was 0.85 for the Nakagami-scaling parameter and was 0.95 for the Nakagami-shape parameter, which further demonstrated the diagnostic efficiency of the Nakagami parameters. Conclusions: Nakagami parameters could be used to quantitatively measure parotid-gland injury following head-and-neck radiotherapy. Moreover, the clinical feasibility was demonstrated and this study provides meaningful preliminary data for future clinical investigation.« less

Ultrasonic Nakagami-parameter characterization of parotid-gland injury following head-and-neck radiotherapy: A feasibility study of late toxicity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yang, Xiaofeng; Wu, Ning; Wang, Yuefeng

2014-02-15

Purpose: The study aims to investigate whether Nakagami parameters—estimated from the statistical distribution of the backscattered ultrasound radio-frequency (RF) signals—could provide a means for quantitative characterization of parotid-gland injury resulting from head-and-neck radiotherapy. Methods: A preliminary clinical study was conducted with 12 postradiotherapy patients and 12 healthy volunteers. Each participant underwent one ultrasound study in which ultrasound scans were performed in the longitudinal, i.e., vertical orientation on the bilateral parotids. For the 12 patients, the mean radiation dose to the parotid glands was 37.7 ± 9.5 Gy, and the mean follow-up time was 16.3 ± 4.8 months. All enrolled patientsmore » experienced grade 1 or 2 late salivary-gland toxicity (RTOG/EORTC morbidity scale). The normal parotid glands served as the control group. The Nakagami-scaling and Nakagami-shape parameters were computed from the RF data to quantify radiation-induced parotid-gland changes. Results: Significant differences in Nakagami parameters were observed between the normal and postradiotherapy parotid glands. Compared with the control group, the Nakagami-scaling parameter of the postradiotherapy group decreased by 25.8% (p < 0.001), and the Nakagami-shape parameter decreased by 31.3% (p < 0.001). The area under the receiver operating characteristic curve was 0.85 for the Nakagami-scaling parameter and was 0.95 for the Nakagami-shape parameter, which further demonstrated the diagnostic efficiency of the Nakagami parameters. Conclusions: Nakagami parameters could be used to quantitatively measure parotid-gland injury following head-and-neck radiotherapy. Moreover, the clinical feasibility was demonstrated and this study provides meaningful preliminary data for future clinical investigation.« less

Low Frequency Radio Experiment (LORE)

NASA Astrophysics Data System (ADS)

Manoharan, P. K.; Naidu, Arun; Joshi, B. C.; Roy, Jayashree; Kate, G.; Pethe, Kaiwalya; Galande, Shridhar; Jamadar, Sachin; Mahajan, S. P.; Patil, R. A.

2016-03-01

In this paper, we present a case study of Low Frequency Radio Experiment (LORE) payload to probe the corona and the solar disturbances at solar offsets greater than 2 solar radii, i.e., at frequencies below 30 MHz. The LORE can be complimentary to the planned Indian solar mission, “Aditya-L1” and its other payloads as well as synergistic to ground-based interplanetary scintillation (IPS) observations, which are routinely carried out by the Ooty Radio Telescope. We discuss the baseline design and technical details of the proposed LORE and its particular suitability for providing measurements on the detailed time and frequency structure of fast drifting type-III and slow drifting type-II radio bursts with unprecedented time and frequency resolutions. We also brief the gonio-polarimetry, which is possible with better-designed antennas and state-of-the-art electronics, employing FPGAs and an intelligent data management system. These would enable us to make a wide range of studies, such as nonlinear plasma processes in the Sun-Earth distance, in-situ radio emission from coronal mass ejections (CMEs), interplanetary CME driven shocks, nature of ICMEs driving decelerating IP shocks and space weather effects of solar wind interaction regions.

Development of a Multi-frequency Interferometer Telescope for Radio Astronomy (MITRA)

NASA Astrophysics Data System (ADS)

Ingala, Dominique Guelord Kumamputu

2015-03-01

This dissertation describes the development and construction of the Multi-frequency Interferometer Telescope for Radio Astronomy (MITRA) at the Durban University of Technology. The MITRA station consists of 2 antenna arrays separated by a baseline distance of 8 m. Each array consists of 8 Log-Periodic Dipole Antennas (LPDAs) operating from 200 MHz to 800 MHz. The design and construction of the LPDA antenna and receiver system is described. The receiver topology provides an equivalent noise temperature of 113.1 K and 55.1 dB of gain. The Intermediate Frequency (IF) stage was designed to produce a fixed IF frequency of 800 MHz. The digital Back-End and correlator were implemented using a low cost Software Defined Radio (SDR) platform and Gnu-Radio software. Gnu-Octave was used for data analysis to generate the relevant received signal parameters including total power, real, and imaginary, magnitude and phase components. Measured results show that interference fringes were successfully detected within the bandwidth of the receiver using a Radio Frequency (RF) generator as a simulated source. This research was presented at the IEEE Africon 2013 / URSI Session Mauritius, and published in the proceedings.

Optimizing sonication protocols for transthoracic focused ultrasound surgery

NASA Astrophysics Data System (ADS)

Gao, J.; Volovick, A.; Cao, R.; Nabi, G.; Cochran, S.; Melzer, A.; Huang, Z.

2012-11-01

During transthoracic focused ultrasound surgery (TFUS), the intervening ribs absorb and reflect the majority of the ultrasound energy excited by an acoustic source, resulting in pain, bone injuries and insufficient energy delivered to the target organs of liver, kidney, and pancreas. Localized hot spots may also exist at the interfaces between the ribs and soft tissue and in the highly absorptive regions such as the skin and connective tissue. The aims of this study were to clarify the effects of focal beam distortion and frequency-dependent rib heating in TFUS and to propose possible techniques to reduce the side-effects of rib heating and increase ultrasound efficacy. Frequency-dependent heating at the target and the ribs were estimated using finite element analysis (PZFlex, Weidlinger Associates Inc, USA) along with experimental verification on a range of different phantoms. The ratio of ultrasonic power density at the target and the ribs, the time-varying spatial distribution of temperature, and the ablated focus of each sonication were taken as key indicators to determine the optimal operating frequency. Comparison with a patient specific model was also made. TFUS seems to be useful to treat tumours that are small and near the surface of the abdominal organs. For targets deep inside these organs, severe attenuation of energy occurs, suggesting that purely ultrasound thermal ablation with advanced heating patterns will have limited effects in improving the treatment efficacy. Results demonstrate that the optimal ultrasound frequency is around 0.8 MHz for the configurations considered, but this may shift to higher frequencies with changes in the axial and lateral positions of the tumours relative to the ribs. To date, we have elucidated the most important effects and correlated these with idealised anatomical geometry. The changes in frequency and other techniques such as selection of excited element patterns in FUS arrays had some effect. However, more advanced techniques need to be explored for further enhanced localised heating in the TFUS study, if this is to prove fully effective.

Sensor Research Targets Smart Building Technology Using Radio-Frequency

Science.gov Websites

a battery-free radio-frequency identification (RFID) sensor network with spatiotemporal pattern network based data fusion system for human presence sensing, with ARPA-E awarding the team $2 million over

Co-registration of ultrasound and frequency-domain photoacoustic radar images and image improvement for tumor detection

NASA Astrophysics Data System (ADS)

Dovlo, Edem; Lashkari, Bahman; Choi, Sung soo Sean; Mandelis, Andreas

2015-03-01

This paper demonstrates the co-registration of ultrasound (US) and frequency domain photoacoustic radar (FD-PAR) images with significant image improvement from applying image normalization, filtering and amplification techniques. Achieving PA imaging functionality on a commercial Ultrasound instrument could accelerate clinical acceptance and use. Experimental results presented demonstrate live animal testing and show enhancements in signal-to-noise ratio (SNR), contrast and spatial resolution. The co-registered image produced from the US and phase PA images, provides more information than both images independently.

Nonlinear oscillation and interfacial stability of an encapsulated microbubble under dual-frequency ultrasound

NASA Astrophysics Data System (ADS)

Calvisi, Michael; Liu, Yunqiao; Wang, Qianxi

2016-11-01

Encapsulated microbubbles (EMBs) are widely used in medical ultrasound imaging as contrast-enhanced agents. However, the potential damaging effects of violent, collapsing EMBs to cells and tissues in clinical practice have remained a concern. Dual-frequency ultrasound is a promising technique for improving the efficacy and safety of sonography. The EMB system modeled consists of the external liquid, membrane, and internal gases. The microbubble dynamics are simulated using a simple nonlinear interactive theory, considering the compressibility of the internal gas, viscosity of the liquid flow, and elasticity of the membrane. The radial oscillation and interfacial stability of an EMB under single and dual-frequency excitations are compared. The simulation results show that the dual-frequency technique produces larger backscatter pressure at higher harmonics of the primary driving frequency. This enriched acoustic spectrum can enhance blood-tissue contrast and improve sonographic image quality. The results further show that the acoustic pressure threshold associated with the onset of shape instability is greater for dual-frequency driving. This suggests that the dual-frequency technique stabilizes the EMB, thereby improving the efficacy and safety of contrast-enhanced agents.

Design and characterization of a high-power ultrasound driver with ultralow-output impedance

NASA Astrophysics Data System (ADS)

Lewis, George K.; Olbricht, William L.

2009-11-01

We describe a pocket-sized ultrasound driver with an ultralow-output impedance amplifier circuit (less than 0.05 Ω) that can transfer more than 99% of the voltage from a power supply to the ultrasound transducer with minimal reflections. The device produces high-power acoustical energy waves while operating at lower voltages than conventional ultrasound driving systems because energy losses owing to mismatched impedance are minimized. The peak performance of the driver is measured experimentally with a PZT-4, 1.54 MHz, piezoelectric ceramic, and modeled using an adjusted Mason model over a range of transducer resonant frequencies. The ultrasound driver can deliver a 100 Vpp (peak to peak) square-wave signal across 0-8 MHz ultrasound transducers in 5 ms bursts through continuous wave operation, producing acoustic powers exceeding 130 W. Effects of frequency, output impedance of the driver, and input impedance of the transducer on the maximum acoustic output power of piezoelectric transducers are examined. The small size, high power, and efficiency of the ultrasound driver make this technology useful for research, medical, and industrial ultrasonic applications.

Design and characterization of a high-power ultrasound driver with ultralow-output impedance.

PubMed

Lewis, George K; Olbricht, William L

2009-11-01

We describe a pocket-sized ultrasound driver with an ultralow-output impedance amplifier circuit (less than 0.05 ohms) that can transfer more than 99% of the voltage from a power supply to the ultrasound transducer with minimal reflections. The device produces high-power acoustical energy waves while operating at lower voltages than conventional ultrasound driving systems because energy losses owing to mismatched impedance are minimized. The peak performance of the driver is measured experimentally with a PZT-4, 1.54 MHz, piezoelectric ceramic, and modeled using an adjusted Mason model over a range of transducer resonant frequencies. The ultrasound driver can deliver a 100 V(pp) (peak to peak) square-wave signal across 0-8 MHz ultrasound transducers in 5 ms bursts through continuous wave operation, producing acoustic powers exceeding 130 W. Effects of frequency, output impedance of the driver, and input impedance of the transducer on the maximum acoustic output power of piezoelectric transducers are examined. The small size, high power, and efficiency of the ultrasound driver make this technology useful for research, medical, and industrial ultrasonic applications.

LOFAR discovery of radio emission in MACS J0717.5+3745

NASA Astrophysics Data System (ADS)

Bonafede, A.; Brüggen, M.; Rafferty, D.; Zhuravleva, I.; Riseley, C. J.; van Weeren, R. J.; Farnes, J. S.; Vazza, F.; Savini, F.; Wilber, A.; Botteon, A.; Brunetti, G.; Cassano, R.; Ferrari, C.; de Gasperin, F.; Orrú, E.; Pizzo, R. F.; Röttgering, H. J. A.; Shimwell, T. W.

2018-05-01

We present results from LOFAR and GMRT observations of the galaxy cluster MACS J0717.5+3745. The cluster is undergoing a violent merger involving at least four sub-clusters, and it is known to host a radio halo. LOFAR observations reveal new sources of radio emission in the Intra-Cluster Medium: (i) a radio bridge that connects the cluster to a head-tail radio galaxy located along a filament of galaxies falling into the main cluster, (ii) a 1.9 Mpc radio arc, that is located North West of the main mass component, (iii) radio emission along the X-ray bar, that traces the gas in the X-rays South West of the cluster centre. We use deep GMRT observations at 608 MHz to constrain the spectral indices of these new radio sources, and of the emission that was already studied in the literature at higher frequency. We find that the spectrum of the radio halo and of the relic at LOFAR frequency follows the same power law as observed at higher frequencies. The radio bridge, the radio arc, and the radio bar all have steep spectra, which can be used to constrain the particle acceleration mechanisms. We argue that the radio bridge could be caused by the re-acceleration of electrons by shock waves that are injected along the filament during the cluster mass assembly. Despite the sensitivity reached by our observations, the emission from the radio halo does not trace the emission of the gas revealed by X-ray observations. We argue that this could be due to the difference in the ratio of kinetic over thermal energy of the intra-cluster gas, suggested by X-ray observations.

Imaging spectroscopy of solar radio burst fine structures.

PubMed

Kontar, E P; Yu, S; Kuznetsov, A A; Emslie, A G; Alcock, B; Jeffrey, N L S; Melnik, V N; Bian, N H; Subramanian, P

2017-11-15

Solar radio observations provide a unique diagnostic of the outer solar atmosphere. However, the inhomogeneous turbulent corona strongly affects the propagation of the emitted radio waves, so decoupling the intrinsic properties of the emitting source from the effects of radio wave propagation has long been a major challenge in solar physics. Here we report quantitative spatial and frequency characterization of solar radio burst fine structures observed with the Low Frequency Array, an instrument with high-time resolution that also permits imaging at scales much shorter than those corresponding to radio wave propagation in the corona. The observations demonstrate that radio wave propagation effects, and not the properties of the intrinsic emission source, dominate the observed spatial characteristics of radio burst images. These results permit more accurate estimates of source brightness temperatures, and open opportunities for quantitative study of the mechanisms that create the turbulent coronal medium through which the emitted radiation propagates.

Hybrid spread spectrum radio system

DOEpatents

Smith, Stephen F [London, TN; Dress, William B [Camas, WA

2010-02-09

Systems and methods are described for hybrid spread spectrum radio systems. A method, includes receiving a hybrid spread spectrum signal including: fast frequency hopping demodulating and direct sequence demodulating a direct sequence spread spectrum signal, wherein multiple frequency hops occur within a single data-bit time and each bit is represented by chip transmissions at multiple frequencies.

Dielectric properties of almond shells in the development of radio frequency and microwave pasteurization

USDA-ARS?s Scientific Manuscript database

To develop pasteurization treatments based on radio frequency (RF) or microwave energy, dielectric properties of almond shells were determined using an open-ended coaxial-probe with an impedance analyzer over a frequency range of 10 to 1800 MHz. Both the dielectric constant and loss factor of almond...

Low-radio-frequency eclipses of the redback pulsar J2215+5135 observed in the image plane with LOFAR.

PubMed

Broderick, J W; Fender, R P; Breton, R P; Stewart, A J; Rowlinson, A; Swinbank, J D; Hessels, J W T; Staley, T D; van der Horst, A J; Bell, M E; Carbone, D; Cendes, Y; Corbel, S; Eislöffel, J; Falcke, H; Grießmeier, J-M; Hassall, T E; Jonker, P; Kramer, M; Kuniyoshi, M; Law, C J; Markoff, S; Molenaar, G J; Pietka, M; Scheers, L H A; Serylak, M; Stappers, B W; Ter Veen, S; van Leeuwen, J; Wijers, R A M J; Wijnands, R; Wise, M W; Zarka, P

2016-07-01

The eclipses of certain types of binary millisecond pulsars (i.e. 'black widows' and 'redbacks') are often studied using high-time-resolution, 'beamformed' radio observations. However, they may also be detected in images generated from interferometric data. As part of a larger imaging project to characterize the variable and transient sky at radio frequencies <200 MHz, we have blindly detected the redback system PSR J2215+5135 as a variable source of interest with the Low-Frequency Array (LOFAR). Using observations with cadences of two weeks - six months, we find preliminary evidence that the eclipse duration is frequency dependent (∝ν -0.4 ), such that the pulsar is eclipsed for longer at lower frequencies, in broad agreement with beamformed studies of other similar sources. Furthermore, the detection of the eclipses in imaging data suggests an eclipsing medium that absorbs the pulsed emission, rather than scattering it. Our study is also a demonstration of the prospects of finding pulsars in wide-field imaging surveys with the current generation of low-frequency radio telescopes.

A Radio-Frequency-over-Fiber link for large-array radio astronomy applications

NASA Astrophysics Data System (ADS)

Mena, J.; Bandura, K.; Cliche, J.-F.; Dobbs, M.; Gilbert, A.; Tang, Q. Y.

2013-10-01

A prototype 425-850 MHz Radio-Frequency-over-Fiber (RFoF) link for the Canadian Hydrogen Intensity Mapping Experiment (CHIME) is presented. The design is based on a directly modulated Fabry-Perot (FP) laser, operating at ambient temperature, and a single-mode fiber. The dynamic performance, gain stability, and phase stability of the RFoF link are characterized. Tests on a two-element interferometer built at the Dominion Radio Astrophysical Observatory for CHIME prototyping demonstrate that RFoF can be successfully used as a cost-effective solution for analog signal transport on the CHIME telescope and other large-array radio astronomy applications.

Mechanism study of multimode ultrasound pretreatment on the enzymolysis of wheat gluten.

PubMed

Zhang, Yanyan; Li, Jing; Li, Suyun; Ma, Haile; Zhang, Hua

2018-03-01

Ultrasound pretreatment could improve the angiotensin-I converting enzyme (ACE) inhibitory activity of hydrolysates of wheat gluten (WG). The working mode of ultrasound has an important effect on the enzymatic hydrolysis of protein. The results showed that the optimum working mode of ultrasound was alternate dual-frequency mode (20/35 kHz), substrate concentration was 30 g L -1 , initial temperature of the suspension was 30 °C, ultrasound pretreatment time was 10 min and power density was 150 W L -1 . Under optimised conditions, ACE inhibitory activity of WG hydrolysates reached to its maximum value in advance. The surface hydrophobicity (H 0 ) of WG and the content of small peptides at the beginning of the enzymolysis were improved by the ultrasound pretreatment. The structure of WG was destroyed by the ultrasound pretreatment. The enzymatic residue of ultrasound pretreated WG were damaged greater than control. It was concluded that alternate dual-frequency ultrasound pretreatment improved the ACE inhibitory activity. Ultrasonic pretreatment may loosen the tissue of WG aggregate, and help the enzyme alcalase to attack the interior of WG aggregate easily, which resulted in the release of low molecular weight peptides from WG aggregate. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

Using low-frequency ultrasound to improve the optical clearing of porcine skin

NASA Astrophysics Data System (ADS)

Zhong, Huiqing; Guo, Zhouyi; Wei, Huajiang; Zhang, Zude; Zeng, Changchun; Zhai, Juan; He, Yonghong

2008-12-01

The glycerol used as an enhancer for tissue optical clearing technique has been researched. However, using it and a physical way of ultrasound enhance optical clearing of tissue reported a few. We researched that the ultrasound whether can improve the optical clearing of dealt with 80% glycerol tissue. The fresh porcine skins divided into four groups. The first group was not dealt with by ultrasound and 80% glycerol, the second group was dealt with by only ultrasound, the third group was dealt with by 80% glycerol and no by ultrasound, and the fourth group was dealt with by both 80% glycerol and ultrasound. And we measured changes in optical scattering of the porcine skins under treatment with OCT. From the OCT images show that the fourth group changed very faster than the other's during the 0~15 min. And it can be clearly seen that there is a significant improvement in the light penetration depth and imaging contrast in a shorter time. It is possible that the low-frequency ultrasound can make disordering of the stratum corneum lipids of the porcine skin (because the cavitation has happened), and improve the speed of 80% glycerol through the stratum corneum of skin. These results proved that using 80% glycerol with the ultrasound can better improve the optical clearing of tissue.

An Optical Receiver Post Processing System for the Integrated Radio and Optical Communications Software Defined Radio Test Bed

NASA Technical Reports Server (NTRS)

Nappier, Jennifer M.; Tokars, Roger P.; Wroblewski, Adam C.

2016-01-01

The Integrated Radio and Optical Communications (iROC) project at the National Aeronautics and Space Administrations (NASA) Glenn Research Center is investigating the feasibility of a hybrid radio frequency (RF) and optical communication system for future deep space missions. As a part of this investigation, a test bed for a radio frequency (RF) and optical software defined radio (SDR) has been built. Receivers and modems for the NASA deep space optical waveform are not commercially available so a custom ground optical receiver system has been built. This paper documents the ground optical receiver, which is used in order to test the RF and optical SDR in a free space optical communications link.

An Optical Receiver Post-Processing System for the Integrated Radio and Optical Communications Software Defined Radio Test Bed

NASA Technical Reports Server (NTRS)

Nappier, Jennifer M.; Tokars, Roger P.; Wroblewski, Adam C.

2016-01-01

The Integrated Radio and Optical Communications (iROC) project at the National Aeronautics and Space Administration's (NASA) Glenn Research Center is investigating the feasibility of a hybrid radio frequency (RF) and optical communication system for future deep space missions. As a part of this investigation, a test bed for a radio frequency (RF) and optical software defined radio (SDR) has been built. Receivers and modems for the NASA deep space optical waveform are not commercially available so a custom ground optical receiver system has been built. This paper documents the ground optical receiver, which is used in order to test the RF and optical SDR in a free space optical communications link.

Pulse-wave propagation in straight-geometry vessels for stiffness estimation: theory, simulations, phantoms and in vitro findings.

PubMed

Shahmirzadi, Danial; Li, Ronny X; Konofagou, Elisa E

2012-11-01

Pulse wave imaging (PWI) is an ultrasound-based method for noninvasive characterization of arterial stiffness based on pulse wave propagation. Reliable numerical models of pulse wave propagation in normal and pathological aortas could serve as powerful tools for local pulse wave analysis and a guideline for PWI measurements in vivo. The objectives of this paper are to (1) apply a fluid-structure interaction (FSI) simulation of a straight-geometry aorta to confirm the Moens-Korteweg relationship between the pulse wave velocity (PWV) and the wall modulus, and (2) validate the simulation findings against phantom and in vitro results. PWI depicted and tracked the pulse wave propagation along the abdominal wall of canine aorta in vitro in sequential Radio-Frequency (RF) ultrasound frames and estimates the PWV in the imaged wall. The same system was also used to image multiple polyacrylamide phantoms, mimicking the canine measurements as well as modeling softer and stiffer walls. Finally, the model parameters from the canine and phantom studies were used to perform 3D two-way coupled FSI simulations of pulse wave propagation and estimate the PWV. The simulation results were found to correlate well with the corresponding Moens-Korteweg equation. A high linear correlation was also established between PWV² and E measurements using the combined simulation and experimental findings (R² =  0.98) confirming the relationship established by the aforementioned equation.

An Analysis of the Defense Acquisition Strategy for Unmanned Systems

DTIC Science & Technology

2013-11-20

Product Service Code RAA Rapid Acquisition Authority RCS Radar Cross Section REF Rapid Equipping Force RFID Radio Frequency Identification RDT...the radio frequency identification (RFID) chip also provides a useful basis for comparison. WWII served as the proving ground for RFID technology...enabling miniaturized Free Space Optical Communications systems capable of scaling across data rates, distances, and platforms and integrating with radio

Direct observations of low-energy solar electrons associated with a type 3 solar radio burst

NASA Technical Reports Server (NTRS)

Frank, L. A.; Gurnett, D. A.

1972-01-01

On 6 April 1971 a solar X-ray flare and a type 3 solar radio noise burst were observed with instrumentation on the eccentric-orbiting satellite IMP 6. The type 3 solar radio noise burst was detected down to a frequency of 31 kHz. A highly anisotropic packet of low-energy solar electron intensities arrived at the satellite approximately 6000 seconds after the onset of the solar flare. This packet of solar electron intensities was observed for 4200 seconds. Maximum differential intensities of the solar electrons were in the energy range of one to several keV. The frequency drift rate of the type 3 radio noise at frequencies below 178 kHz also indicated an average particle speed corresponding to that of a 3-keV electron. The simultaneous observations of these solar electron intensities and of the type 3 solar radio burst are presented, and their interrelationships are explored.

Grating formation by a high power radio wave in near-equator ionosphere

DOE Office of Scientific and Technical Information (OSTI.GOV)

Singh, Rohtash; Sharma, A. K.; Tripathi, V. K.

2011-11-15

The formation of a volume grating in the near-equator regions of ionosphere due to a high power radio wave is investigated. The radio wave, launched from a ground based transmitter, forms a standing wave pattern below the critical layer, heating the electrons in a space periodic manner. The thermal conduction along the magnetic lines of force inhibits the rise in electron temperature, limiting the efficacy of heating to within a latitude of few degrees around the equator. The space periodic electron partial pressure leads to ambipolar diffusion creating a space periodic density ripple with wave vector along the vertical. Suchmore » a volume grating is effective to cause strong reflection of radio waves at a frequency one order of magnitude higher than the maximum plasma frequency in the ionosphere. Linearly mode converted plasma wave could scatter even higher frequency radio waves.« less

Improved fire resistant radio frequency anechoic materials

NASA Technical Reports Server (NTRS)

Robinson, D. A.

1969-01-01

Protective, flameproof foam covering improves the resistance to fire and surface contamination of low-cost radio frequency absorbing and shielding anechoic materials. This promotes safety of operating personnel and equipment being tested in an otherwise combustible anechoic chamber.

Base-level management of radio-frequency radiation-protection program. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rademacher, S.E.; Montgomery, N.D.

1989-04-01

AFOEHL developed this report to assist the base-level aerospace medical team manage their radio-frequency radiation-protection program. This report supersedes USAFOEHL Report 80-42, 'A Practical R-F Guide for BEES.'

Base-level management of radio-frequency radiation-protection program. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rademacher, S.E.; Montgomery, N.D.

1989-04-01

AFOEHL developed this report to assist the base-level aerospace medical team manage their radio-frequency radiation protection program. This report supersedes USAFOEHL Report 80-42, 'A practical R-F Guide for BEES.'

Large-signal model of the bilayer graphene field-effect transistor targeting radio-frequency applications: Theory versus experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pasadas, Francisco, E-mail: Francisco.Pasadas@uab.cat; Jiménez, David

2015-12-28

Bilayer graphene is a promising material for radio-frequency transistors because its energy gap might result in a better current saturation than the monolayer graphene. Because the great deal of interest in this technology, especially for flexible radio-frequency applications, gaining control of it requires the formulation of appropriate models for the drain current, charge, and capacitance. In this work, we have developed them for a dual-gated bilayer graphene field-effect transistor. A drift-diffusion mechanism for the carrier transport has been considered coupled with an appropriate field-effect model taking into account the electronic properties of the bilayer graphene. Extrinsic resistances have been includedmore » considering the formation of a Schottky barrier at the metal-bilayer graphene interface. The proposed model has been benchmarked against experimental prototype transistors, discussing the main figures of merit targeting radio-frequency applications.« less

Use of mobile phones and cancer risk.

PubMed

Ayanda, Olushola S; Baba, Alafara A; Ayanda, Omolola T

2012-01-01

Mobile phones work by transmitting and receiving radio frequency microwave radiation. The radio frequency (RF) emitted by mobile phones is stronger than FM radio signal which are known to cause cancer. Though research and evidence available on the risk of cancer by mobile phones does not provide a clear and direct support that mobile phones cause cancers. Evidence does not also support an association between exposure to radio frequency and microwave radiation from mobile phones and direct effects on health. It is however clear that lack of available evidence of cancer as regards the use of mobile phone should not be interpreted as proof of absence of cancer risk, so that excessive use of mobile phones should be taken very seriously and with caution to prevent cancer.

Software Configurable Multichannel Transceiver

NASA Technical Reports Server (NTRS)

Freudinger, Lawrence C.; Cornelius, Harold; Hickling, Ron; Brooks, Walter

2009-01-01

Emerging test instrumentation and test scenarios increasingly require network communication to manage complexity. Adapting wireless communication infrastructure to accommodate challenging testing needs can benefit from reconfigurable radio technology. A fundamental requirement for a software-definable radio system is independence from carrier frequencies, one of the radio components that to date has seen only limited progress toward programmability. This paper overviews an ongoing project to validate the viability of a promising chipset that performs conversion of radio frequency (RF) signals directly into digital data for the wireless receiver and, for the transmitter, converts digital data into RF signals. The Software Configurable Multichannel Transceiver (SCMT) enables four transmitters and four receivers in a single unit the size of a commodity disk drive, programmable for any frequency band between 1 MHz and 6 GHz.

Radio Frequency Signals in Jupiter's Atmosphere

PubMed

Lanzerotti; Rinnert; Dehmel; Gliem; Krider; Uman; Bach

1996-05-10

During the Galileo probe's descent through Jupiter's atmosphere, under the ionosphere, the lightning and radio emission detector measured radio frequency signals at levels significantly above the probe's electromagnetic noise. The signal strengths at 3 and 15 kilohertz were relatively large at the beginning of the descent, decreased with depth to a pressure level of about 5 bars, and then increased slowly until the end of the mission. The 15-kilohertz signals show arrival direction anisotropies. Measurements of radio frequency wave forms show that the probe passed through an atmospheric region that did not support lightning within at least 100 kilometers and more likely a few thousand kilometers of the descent trajectory. The apparent opacity of the jovian atmosphere increases sharply at pressures greater than about 4 bars.

Radio Spectral Imaging of Reflective MHD Waves during the Impulsive Phase of a Solar Flare

NASA Astrophysics Data System (ADS)

Yu, S.; Chen, B.; Reeves, K.

2017-12-01

We report a new type of coherent radio bursts observed by the Karl G. Jansky Very Large Array (VLA) in 1-2 GHz during the impulsive phase of a two-ribbon flare on 2014 November 1, which we interpret as MHD waves reflected near the footpoint of flaring loops. In the dynamic spectrum, this burst starts with a positive frequency drift toward higher frequencies until it slows down near its highest-frequency boundary. Then it turns over and drifts toward lower frequencies. The frequency drift rate in its descending and ascending branch is between 50-150 MHz/s, which is much slower than type III radio bursts associated with fast electron beams but close to the well-known intermediate drift bursts, or fiber bursts, which are usually attributed to propagating whistler or Alfvenic waves. Thanks to VLA's unique capability of imaging with spectrometer-like temporal and spectral resolution (50 ms and 2 MHz), we are able to obtain an image of the radio source at every time and frequency in the dynamic spectrum where the burst is present and trace its spatial evolution. From the imaging results, we find that the radio source firstly moves downward toward one of the flaring ribbons before it "bounces off" at the lowest height (corresponding to the turnover frequency in the dynamic spectrum) and moves upward again. The measured speed in projection is at the order of 1-2 Mm/s, which is characteristic of Alfvenic or fast-mode MHD waves in the low corona. We conclude that the radio burst is emitted by trapped nonthermal electrons in the flaring loop carried along by a large-scale MHD wave. The waves are probably launched during the eruption of a magnetic flux rope in the flare impulsive phase.

The Spectrum Landscape: Prospects for Terrestrial Radio Astronomy

NASA Astrophysics Data System (ADS)

Liszt, Harvey Steven

2018-01-01

Radio astronomers work within broad constraints imposed by commercial and other non-astronomical uses of the radio spectrum, somewhat modified to accommodate astronomy’s particular needs through the provision of radio quiet zones, radio frequency allocations, coordination agreements and other devices of spectrum management. As radio astronomers increase the instantaneous bandwidth, frequency coverage and sensitivity of their instruments, these external constraints, and not the limitations of their own instruments, will increasingly be the greatest obstacles to radio astronomy’s ability to observe the cosmos from the surface of the Earth. Therefore, prospects for future radio astronomy operations are contingent on situational awareness and planning for the impact of non-astronomical uses of the radio frequency spectrum. New radio astronomy instruments will have to incorporate adaptive reactions to external developments, and radio astronomers should be encouraged to think in untraditional ways. Increased attention to spectrum management is one of these. In this talk I’ll recap some recent developments such as the proliferation of 76 – 81 GHz car radar and orbiting earth-mapping radars, either of which can burn out a radio astronomy receiver. I’ll summarize present trends for non-astronomical radio spectrum use that will be coming to fruition in the next decade or so, categorized into terrestrial fixed and mobile, airborne and space-borne uses, sub-divided by waveband from the cm to the sub-mm. I’ll discuss how they will impact terrestrial radio astronomy and the various ways in which radio astronomy should be prepared to react. Protective developments must occur both within radio astronomy’s own domain – designing, siting and constructing its instruments and mitigating unavoidable RFI – and facing outward toward the community of other spectrum users. Engagement with spectrum management is no panacea but it is an important means, and perhaps the only means, by which radio astronomy can take an active role in shaping its terrestrial environment.

Surface modification of lignocellulosic fibers using high-frequency ultrasound

Treesearch

Jayant B. Gadhe; Ram B. Gupta; Thomas Elder

2005-01-01

Enzymatic and chemical oxidation of fiber surfaces has been reported in the literature as a method for producing medium density fiberboards without using synthetic adhesives. This work focuses on modifying the surface properties of wood fibers by the generation of free radicals using high-frequency ultrasound. A sonochemical reactor operating at 610 kHz is used to...

Clinical Utility of High-Frequency Musculoskeletal Ultrasonography in Foot and Ankle Pathology: How Ultrasound Imaging Influences Diagnosis and Management.

PubMed

Delzell, Patricia B; Tritle, Benjamin A; Bullen, Jennifer A; Chiunda, Stella; Forney, Michael C

The use of high-frequency (high-resolution) musculoskeletal ultrasonography is increasing and has shown promising utility in many areas of medicine. The utility of musculoskeletal ultrasonography for foot and ankle complaints has not been widely investigated, however. Although some conditions of the foot and ankle are easily diagnosed by physical examination, others can have nonspecific examination findings, making optimal treatment decisions difficult. We hypothesized that high-resolution musculoskeletal ultrasound scanning of the foot and ankle can affect the diagnosis and/or treatment for patients presenting with foot or ankle complaints. Retrospectively, the cases of 98 patients who had undergone musculoskeletal ultrasound scanning of the foot or ankle were reviewed. The pre-ultrasound clinical diagnosis and treatment were compared with the post-ultrasound diagnosis and treatment. In 64% of the patients, the diagnosis or treatment changed after the ultrasound examination. In 43% of patients, both the diagnosis and the treatment changed after ultrasound scanning. For those patients for whom the diagnosis and treatment were unchanged after the ultrasound examination, the ultrasound findings were concordant with the pre-ultrasound clinical diagnosis for 100% of the patients. These results suggest that in a large proportion of patients, high-resolution musculoskeletal ultrasonography of the foot or ankle can facilitate appropriate diagnosis and management. Copyright © 2017 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

Selective and Catalyst-free Oxidation of D-Glucose to D-Glucuronic acid induced by High-Frequency Ultrasound

NASA Astrophysics Data System (ADS)

Amaniampong, Prince N.; Karam, Ayman; Trinh, Quang Thang; Xu, Kai; Hirao, Hajime; Jérôme, François; Chatel, Gregory

2017-01-01

This systematic experimental investigation reveals that high-frequency ultrasound irradiation (550 kHz) induced oxidation of D-glucose to glucuronic acid in excellent yield without assistance of any (bio)catalyst. Oxidation is induced thanks to the in situ production of radical species in water. Experiments show that the dissolved gases play an important role in governing the nature of generated radical species and thus the selectivity for glucuronic acid. Importantly, this process yields glucuronic acid instead of glucuronate salt typically obtained via conventional (bio)catalyst routes, which is of huge interest in respect of downstream processing. Investigations using disaccharides revealed that radicals generated by high frequency ultrasound were also capable of promoting tandem hydrolysis/oxidation reactions.

Dual-frequency focused ultrasound using optoacoustic and piezoelectric transmitters for single-pulsed free-field cavitation in water

NASA Astrophysics Data System (ADS)

Baac, Hyoung Won; Lee, Taehwa; Ok, Jong G.; Hall, Timothy; Jay Guo, L.

2013-12-01

Pulsed ultrasonic cavitation is a promising modality for non-contact targeted therapy, enabling mechanical ablation of the tissue. We demonstrate a spatio-temporal superposition approach of two ultrasound pulses (high and low frequencies) producing a tight cavitation zone of 100 μm in water, which is an-order-of-magnitudes smaller than those obtained by the existing high-amplitude transducers. Particularly, laser-generated focused ultrasound (LGFU) was employed for the high-frequency operation (15 MHz). As demonstrated, LGFU plays a primary role to define the cavitation zone. The generation rate of cavitation bubbles could be dramatically increased up to 4.1% (cf. 0.06% without the superposition) with moderated threshold requirement.

High frequency ultrasound with color Doppler in dermatology*

PubMed Central

Barcaui, Elisa de Oliveira; Carvalho, Antonio Carlos Pires; Lopes, Flavia Paiva Proença Lobo; Piñeiro-Maceira, Juan; Barcaui, Carlos Baptista

2016-01-01

Ultrasonography is a method of imaging that classically is used in dermatology to study changes in the hypoderma, as nodules and infectious and inflammatory processes. The introduction of high frequency and resolution equipments enabled the observation of superficial structures, allowing differentiation between skin layers and providing details for the analysis of the skin and its appendages. This paper aims to review the basic principles of high frequency ultrasound and its applications in different areas of dermatology. PMID:27438191

New radio meteor detecting and logging software

NASA Astrophysics Data System (ADS)

Kaufmann, Wolfgang

2017-08-01

A new piece of software ``Meteor Logger'' for the radio observation of meteors is described. It analyses an incoming audio stream in the frequency domain to detect a radio meteor signal on the basis of its signature, instead of applying an amplitude threshold. For that reason the distribution of the three frequencies with the highest spectral power are considered over the time (3f method). An auto notch algorithm is developed to prevent the radio meteor signal detection from being jammed by a present interference line. The results of an exemplary logging session are discussed.

Rydberg-atom based radio-frequency electrometry using frequency modulation spectroscopy in room temperature vapor cells.

PubMed

Kumar, Santosh; Fan, Haoquan; Kübler, Harald; Jahangiri, Akbar J; Shaffer, James P

2017-04-17

Rydberg atom-based electrometry enables traceable electric field measurements with high sensitivity over a large frequency range, from gigahertz to terahertz. Such measurements are particularly useful for the calibration of radio frequency and terahertz devices, as well as other applications like near field imaging of electric fields. We utilize frequency modulated spectroscopy with active control of residual amplitude modulation to improve the signal to noise ratio of the optical readout of Rydberg atom-based radio frequency electrometry. Matched filtering of the signal is also implemented. Although we have reached similarly, high sensitivity with other read-out methods, frequency modulated spectroscopy is advantageous because it is well-suited for building a compact, portable sensor. In the current experiment, ∼3 µV cm^-1 Hz^-1/2 sensitivity is achieved and is found to be photon shot noise limited.

Comparison of low and high frequency transducers in the detection of liver metastases.

PubMed

Schacherer, D; Wrede, C; Obermeier, F; Schölmerich, J; Schlottmann, K; Klebl, F

2006-09-01

To evaluate the benefit of the additional use of a high frequency ultrasound probe (7.5 MHz) in finding suspicious liver lesions compared to the examination using a 3.5-MHz transducer only. One hundred and fifty-seven patients with underlying malignant disease were examined with both transducers using one of three ultrasound machines (Siemens Sonoline Elegra, GE Healthcare Logic 9, or Hitachi EUB-8500). Findings on hepatic lesions were collected on a standardised documentation sheet and evaluated by descriptive statistics. Ninety-three patients (59.2% of all patients) showed no evident liver lesion on conventional ultrasound with the 3.5 MHz probe. In 29 patients (18.5%) new suspicious liver lesions were found by using the high frequency transducer. Thirteen of these 29 patients (44.8%) were suspected to suffer from diffuse infiltration of the liver with malignant lesions or at least 10 additional visible lesions. In 14 patients, no liver lesion had been known before high frequency ultrasound examination. The size of newly described liver lesions ranged from 2 mm to 1.5 cm. Time needed for the additional examination with the high frequency transducer ranged between 1 and 15 min with an average of 4.0 min. The additional use of a high frequency transducer in patients with underlying malignant disease slightly extends the examination time, but reveals new, potentially malignant hepatic lesions in almost every fifth patient.

POST-OUTBURST RADIO OBSERVATIONS OF THE HIGH MAGNETIC FIELD PULSAR PSR J1119-6127

DOE Office of Scientific and Technical Information (OSTI.GOV)

Majid, Walid A.; Pearlman, Aaron B.; Dobreva, Tatyana

We have carried out high-frequency radio observations of the high magnetic field pulsar PSR J1119-6127 following its recent X-ray outburst. While initial observations showed no evidence of significant radio emission, subsequent observations detected pulsed emission across a large frequency band. In this Letter, we report on the initial disappearance of the pulsed emission and its prompt reactivation and dramatic evolution over several months of observation. The periodic pulse profile at S -band (2.3 GHz) after reactivation exhibits a multi-component emission structure, while the simultaneous X -band (8.4 GHz) profile shows a single emission peak. Single pulses were also detected atmore » S -band near the main emission peaks. We present measurements of the spectral index across a wide frequency bandwidth, which captures the underlying changes in the radio emission profile of the neutron star. The high-frequency radio detection, unusual emission profile, and observed variability suggest similarities with magnetars, which may independently link the high-energy outbursts to magnetar-like behavior.« less

The radio spectral energy distribution of infrared-faint radio sources

NASA Astrophysics Data System (ADS)

Herzog, A.; Norris, R. P.; Middelberg, E.; Seymour, N.; Spitler, L. R.; Emonts, B. H. C.; Franzen, T. M. O.; Hunstead, R.; Intema, H. T.; Marvil, J.; Parker, Q. A.; Sirothia, S. K.; Hurley-Walker, N.; Bell, M.; Bernardi, G.; Bowman, J. D.; Briggs, F.; Cappallo, R. J.; Callingham, J. R.; Deshpande, A. A.; Dwarakanath, K. S.; For, B.-Q.; Greenhill, L. J.; Hancock, P.; Hazelton, B. J.; Hindson, L.; Johnston-Hollitt, M.; Kapińska, A. D.; Kaplan, D. L.; Lenc, E.; Lonsdale, C. J.; McKinley, B.; McWhirter, S. R.; Mitchell, D. A.; Morales, M. F.; Morgan, E.; Morgan, J.; Oberoi, D.; Offringa, A.; Ord, S. M.; Prabu, T.; Procopio, P.; Udaya Shankar, N.; Srivani, K. S.; Staveley-Smith, L.; Subrahmanyan, R.; Tingay, S. J.; Wayth, R. B.; Webster, R. L.; Williams, A.; Williams, C. L.; Wu, C.; Zheng, Q.; Bannister, K. W.; Chippendale, A. P.; Harvey-Smith, L.; Heywood, I.; Indermuehle, B.; Popping, A.; Sault, R. J.; Whiting, M. T.

2016-10-01

Context. Infrared-faint radio sources (IFRS) are a class of radio-loud (RL) active galactic nuclei (AGN) at high redshifts (z ≥ 1.7) that are characterised by their relative infrared faintness, resulting in enormous radio-to-infrared flux density ratios of up to several thousand. Aims: Because of their optical and infrared faintness, it is very challenging to study IFRS at these wavelengths. However, IFRS are relatively bright in the radio regime with 1.4 GHz flux densities of a few to a few tens of mJy. Therefore, the radio regime is the most promising wavelength regime in which to constrain their nature. We aim to test the hypothesis that IFRS are young AGN, particularly GHz peaked-spectrum (GPS) and compact steep-spectrum (CSS) sources that have a low frequency turnover. Methods: We use the rich radio data set available for the Australia Telescope Large Area Survey fields, covering the frequency range between 150 MHz and 34 GHz with up to 19 wavebands from different telescopes, and build radio spectral energy distributions (SEDs) for 34 IFRS. We then study the radio properties of this class of object with respect to turnover, spectral index, and behaviour towards higher frequencies. We also present the highest-frequency radio observations of an IFRS, observed with the Plateau de Bure Interferometer at 105 GHz, and model the multi-wavelength and radio-far-infrared SED of this source. Results: We find IFRS usually follow single power laws down to observed frequencies of around 150 MHz. Mostly, the radio SEDs are steep (α < -0.8; %), but we also find ultra-steep SEDs (α < -1.3; %). In particular, IFRS show statistically significantly steeper radio SEDs than the broader RL AGN population. Our analysis reveals that the fractions of GPS and CSS sources in the population of IFRS are consistent with the fractions in the broader RL AGN population. We find that at least % of IFRS contain young AGN, although the fraction might be significantly higher as suggested by the steep SEDs and the compact morphology of IFRS. The detailed multi-wavelength SED modelling of one IFRS shows that it is different from ordinary AGN, although it is consistent with a composite starburst-AGN model with a star formation rate of 170 M⊙ yr-1. Based on observations carried out with the IRAM Plateau de Bure Interferometer. IRAM is supported by INSU/CNRS (France), MPG (Germany) and IGN (Spain).

Investigating the sonophoresis effect on the permeation of diclofenac sodium using 3D skin equivalent.

PubMed

Aldwaikat, Mai; Alarjah, Mohammed

2015-01-01

Ultrasound temporally increases skin permeability by altering stratum corneum SC function (sonophoresis). The objective of this study was to evaluate the effect of variable ultrasound conditions on the permeation of diclofenac sodium DS with range of physicochemical properties through EpiDerm™. Permeation studies were carried out in vitro using Franz diffusion cell. HPLC method was used for the determination of the concentration of diclofenac sodium in receiving compartment. Parameters like ultrasound frequency, application time, amplitude, and mode of sonication and distance of ultrasound horn from skin were investigated, and the conditions where the maximum enhancement rate obtained were determined. Application of ultrasound enhanced permeation of diclofenac sodium across EpiDerm™ by fivefolds. The most effective enhancing parameters were power sonication of 20kHz frequency, 20% amplitude at continuous mode for 5min. Copyright © 2014. Published by Elsevier B.V.

Effect of high power low frequency ultrasound processing on the stability of lycopene.

PubMed

Oliveira, Valéria S; Rodrigues, Sueli; Fernandes, Fabiano A N

2015-11-01

The stability of lycopene was evaluated after application of high power low frequency ultrasound. The study was carried out on a solution containing pure lycopene to evaluate the direct effect of ultrasound on lycopene and on tomato purée to evaluate the direct and indirect effects of ultrasound application within a food matrix. Power densities ranging from 55 to 5000 W/L and temperatures ranging from 23°C (ambient) to 60°C were evaluated. The experiments on pure lycopene showed that the application of ultrasound did not have any direct effect over lycopene. However, the retention of lycopene in tomato puree has decreased indicating an indirect effect on lycopene stability caused by high concentration of hydrogen peroxide and the activation of peroxidase enzymes leading to the reduction of ascorbic acid and its regenerative action towards lycopene. Copyright © 2015 Elsevier B.V. All rights reserved.

Quasiperiodic oscillations of the sub-mHz band in near-sun plasma according to the coherent radio occultation data

NASA Astrophysics Data System (ADS)

Efimov, A. I.; Lukanina, L. A.; Chashei, I. V.; Kolomiets, S. F.; Bird, M. K.; Pätzold, M.

2018-01-01

In 2013 and 2015, investigations of the internal solar wind were carried out using the method of two-frequency radio sounding by signals from the Mars Express European spacecraft. The values of the S- and X-bands' frequency and the differential frequency were registered with a sampling rate of 1s at the American and European networks of ground-based tracking stations. The spatial distribution of the frequency fluctuation's level has been studied. It has been shown that the intensity of frequency fluctuation considerably decreases at high heliolatitudes. In some radio sounding sessions, quasiperiodic oscillations of sub-mHz band have been observed in the temporal spectra of frequency fluctuations; they are supposed to be associated with the density inhomogeneities, the sizes of which are close to the turbulence outer scale.

Low-frequency Radio Observatory on the Lunar Surface (LROLS)

NASA Astrophysics Data System (ADS)

MacDowall, Robert; Network for Exploration and Space Science (NESS)

2018-06-01

A radio observatory on the lunar surface will provide the capability to image solar radio bursts and other sources. Radio burst imaging will improve understanding of radio burst mechanisms, particle acceleration, and space weather. Low-frequency observations (less than ~20 MHz) must be made from space, because lower frequencies are blocked by Earth’s ionosphere. Solar radio observations do not mandate an observatory on the farside of the Moon, although such a location would permit study of less intense solar bursts because the Moon occults the terrestrial radio frequency interference. The components of the lunar radio observatory array are: the antenna system consisting of 10 – 100 antennas distributed over a square kilometer or more; the system to transfer the radio signals from the antennas to the central processing unit; electronics to digitize the signals and possibly to calculate correlations; storage for the data until it is down-linked to Earth. Such transmission requires amplification and a high-gain antenna system or possibly laser comm. For observatories on the lunar farside a satellite or other intermediate transfer system is required to direct the signal to Earth. On the ground, the aperture synthesis analysis is completed to display the radio image as a function of time. Other requirements for lunar surface systems include the power supply, utilizing solar arrays with batteries to maintain the system at adequate thermal levels during the lunar night. An alternative would be a radioisotope thermoelectric generator requiring less mass. The individual antennas might be designed with their own solar arrays and electronics to transmit data to the central processing unit, but surviving lunar night would be a challenge. Harnesses for power and data transfer from the central processing unit to the antennas are an alternative, but a harness-based system complicates deployment. The concept of placing the antennas and harnesses on rolls of polyimide and rolling them out may be a solution for solar radio observations, but it probably does not provide a sufficiently-uniform beam for other science targets.

CAVITIES AND SHOCKS IN THE GALAXY GROUP HCG 62 AS REVEALED BY CHANDRA, XMM-NEWTON, AND GIANT METREWAVE RADIO TELESCOPE DATA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gitti, Myriam; O'Sullivan, Ewan; Giacintucci, Simona

2010-05-01

We report on the results of an analysis of Chandra, XMM-Newton, and new Giant Metrewave Radio Telescope (GMRT) data of the X-ray bright compact group of galaxies HCG 62, which is one of the few groups known to possess clear, small X-ray cavities in the inner regions. This is part of an ongoing X-ray/low-frequency radio study of 18 groups, initially chosen for the availability of good-quality X-ray data and evidence for active galactic nucleus/hot gas interaction. At higher frequency (1.4 GHz), the HCG 62 cavity system shows minimal if any radio emission, but the new GMRT observations at 235 MHzmore » and 610 MHz clearly detect extended low-frequency emission from radio lobes corresponding to the cavities. By means of the synergy of X-ray and low-frequency radio observations, we compare and discuss the morphology, luminosity, and pressure of the gas and of the radio source. We find that the radio source is radiatively inefficient, with a ratio of radio luminosity to mechanical cavity power of {approx}10{sup -4}, and that the radio pressure of the lobes is about 1 order of magnitude lower than the X-ray pressure of the surrounding thermal gas. Thanks to the high spatial resolution of the Chandra surface brightness and temperature profiles, we also identify a shock front located at 36 kpc to the southwest of the group center, close to the southern radio lobe, with a Mach number {approx}1.5 and a total power which is about 1 order of magnitude higher than the cavity power. Such a shock may have heated the gas in the southern region, as indicated by the temperature map. The shock may also explain the arc-like region of enriched gas seen in the iron abundance map, as this may be produced by a non-Maxwellian electron distribution near its front.« less

Synchrotron Spectral Curvature from 22 MHZ to 23 GHZ

NASA Technical Reports Server (NTRS)

Kogut, Alan J.

2012-01-01

We combine surveys of the radio sky at frequencies 22 MHz to 1.4 GHz with data from the ARCADE-2 instrument at frequencies 3 GHz to 10 GHz to characterize the frequency spectrum of diffuse synchrotron emission in the Galaxy. The radio spectrum steepens with frequency from 22 MHz to 10 GHz. The projected spectral index at 23 GHz derived from the low-frequency data agrees well with independent measurements using only data at frequencies 23 GHz and above. Comparing the spectral index at 23 GHz to the value from previously published analyses allows extension of the model to higher frequencies. The combined data are consistent with a power-law index beta = -2.64 +/-= 0.03 at 0.31 GHz, steepening by an amount of Delta-beta = 0.07 every octave in frequency. Comparison of the radio data to models including the cosmic-ray energy spectrum suggests that any break in the synchrotron spectrum must occur at frequencies above 23 GHz.

Design, Fabrication and Characterization of A Bi-Frequency Co-Linear Array

PubMed Central

Wang, Zhuochen; Li, Sibo; Czernuszewicz, Tomasz J; Gallippi, Caterina M.; Liu, Ruibin; Geng, Xuecang

2016-01-01

Ultrasound imaging with high resolution and large penetration depth has been increasingly adopted in medical diagnosis, surgery guidance, and treatment assessment. Conventional ultrasound works at a particular frequency, with a −6 dB fractional bandwidth of ~70 %, limiting the imaging resolution or depth of field. In this paper, a bi-frequency co-linear array with resonant frequencies of 8 MHz and 20 MHz was investigated to meet the requirements of resolution and penetration depth for a broad range of ultrasound imaging applications. Specifically, a 32-element bi-frequency co-linear array was designed and fabricated, followed by element characterization and real-time sectorial scan (S-scan) phantom imaging using a Verasonics system. The bi-frequency co-linear array was tested in four different modes by switching between low and high frequencies on transmit and receive. The four modes included the following: (1) transmit low, receive low, (2) transmit low, receive high, (3) transmit high, receive low, (4) transmit high, receive high. After testing, the axial and lateral resolutions of all modes were calculated and compared. The results of this study suggest that bi-frequency co-linear arrays are potential aids for wideband fundamental imaging and harmonic/sub-harmonic imaging. PMID:26661069

Effects of the 2017 Solar Eclipse on HF Radio Propagation and the D-Region Ionosphere: Citizen Science Investigation

NASA Astrophysics Data System (ADS)

Fry, C. D.; Adams, M.; Gallagher, D. L.; Habash Krause, L.; Rawlins, L.; Suggs, R. M.; Anderson, S. C.

2017-12-01

August 21, 2017 provided a unique opportunity to investigate the effects of the total solar eclipse on high frequency (HF) radio propagation and ionospheric variability. In Marshall Space Flight Center's partnership with the US Space and Rocket Center (USSRC) and Austin Peay State University (APSU), we engaged students and citizen scientists in an investigation of the eclipse effects on the mid-latitude ionosphere. The Amateur Radio community has developed several automated receiving and reporting networks that draw from widely-distributed, automated and manual radio stations to build a near-real time, global picture of changing radio propagation conditions. We used these networks and employed HF radio propagation modeling in our investigation. A Ham Radio Science Citizen Investigation (HamSCI) collaboration with the American Radio Relay League (ARRL) ensured that many thousands of amateur radio operators would be "on the air" communicating on eclipse day, promising an extremely large quantity of data would be collected. Activities included implementing and configuring software, monitoring the HF Amateur Radio frequency bands and collecting radio transmission data on days before, the day of, and days after the eclipse to build a continuous record of changing propagation conditions as the moon's shadow marched across the United States. Our expectations were the D-Region ionosphere would be most impacted by the eclipse, enabling over-the-horizon radio propagation on lower HF frequencies (3.5 and 7 MHz) that are typically closed during the middle of the day. Post-eclipse radio propagation analysis provided insights into ionospheric variability due to the eclipse. We report on results, interpretation, and conclusions of these investigations.

Application of chemometrics to assess the influence of ultrasound frequency, Lactobacillus sakei culture and drying on beef jerky manufacture: Impact on amino acid profile, organic acids, texture and colour.

PubMed

Shikha Ojha, K; Granato, Daniel; Rajuria, Gaurav; Barba, Francisco J; Kerry, Joseph P; Tiwari, Brijesh K

2018-01-15

The effects of ultrasound (US) frequency, addition of Lactobacillus sakei culture and drying time on key nutritional (protein, amino acids, and organic acids) and physicochemical properties (texture and colour) of cultured and uncultured beef jerky were evaluated. Cultured and uncultured jerky samples were subjected to US frequencies of 25kHz, 33kHz and 45kHz for 30min prior to marination and drying. Principal component analysis demonstrated a significant effect of beef jerky processing conditions on physicochemical properties. Taurine content of jerky samples was found to increase with an increase in ultrasonic frequencies for cultured samples. No significant changes in colour values were observed for ultrasound pre-treated and control samples. Interactive effects of culture treatment, drying and ultrasonic frequency were observed. This study demonstrates that the nutritional profile of beef jerky can be improved through the incorporation of L. sakei. Copyright © 2017 Elsevier Ltd. All rights reserved.

Causes and mitigation of radio frequency (RF) blackout during reentry of reusable launch vehicles

DOT National Transportation Integrated Search

2007-01-26

The Aerospace Corporation was tasked to assess radio frequency (RF) blackout phenomena caused by plasma generation around vehicles during reentry and presently known methodologies for mitigation of this condition inhibiting communications. The purpos...

Prospects of Biometrics at-a-Distance

DTIC Science & Technology

2015-09-01

PHI Protected Health Information RFID Radio-Frequency Identification SAF Small Arms Fire SEEK Secure Electronic Enrollment Kit SFPD San...data to be encoded. It also contains a Radio-Frequency Identification ( RFID ) readers and the capability to verify electronic passports and other

Radio-Frequency and Wideband Modulation Arraying

NASA Technical Reports Server (NTRS)

Brockman, M. H.

1984-01-01

Summing network receives coherent signals from all receivers in array. Method sums narrow-band radio-frequency (RF) carrier powers and wide-band spectrum powers of array of separate antenna/receiver systems designed for phase-locked-loop or suppressed-carrier operation.

Radio Flares from Gamma-ray Bursts

NASA Astrophysics Data System (ADS)

Kopač, D.; Mundell, C. G.; Kobayashi, S.; Virgili, F. J.; Harrison, R.; Japelj, J.; Guidorzi, C.; Melandri, A.; Gomboc, A.

2015-06-01

We present predictions of centimeter and millimeter radio emission from reverse shocks (RSs) in the early afterglows of gamma-ray bursts (GRBs) with the goal of determining their detectability with current and future radio facilities. Using a range of GRB properties, such as peak optical brightness and time, isotropic equivalent gamma-ray energy, and redshift, we simulate radio light curves in a framework generalized for any circumburst medium structure and including a parameterization of the shell thickness regime that is more realistic than the simple assumption of thick- or thin-shell approximations. Building on earlier work by Mundell et al. and Melandri et al. in which the typical frequency of the RS was suggested to lie at radio rather than optical wavelengths at early times, we show that the brightest and most distinct RS radio signatures are detectable up to 0.1-1 day after the burst, emphasizing the need for rapid radio follow-up. Detection is easier for bursts with later optical peaks, high isotropic energies, lower circumburst medium densities, and at observing frequencies that are less prone to synchrotron self-absorption effects—typically above a few GHz. Given recent detections of polarized prompt gamma-ray and optical RS emission, we suggest that detection of polarized radio/millimeter emission will unambiguously confirm the presence of low-frequency RSs at early time.

Observing Solar Radio Bursts from the Lunar Surface

NASA Technical Reports Server (NTRS)

MacDowall, R. J.; Lazio, T. J.; Bale, S. D.; Burns, J.; Gopalswamy, N.; Jones, D. L.; Kaiser, M. L.; Kasper, J.; Weiler, K. W.

2010-01-01

Locating low frequency radio observatories on the lunar surface has a number of advantages. Here, we describe the Radio Observatory for Lunar Sortie Science (ROLSS), a concept for a low frequency, radio imaging interferometric array designed to study particle acceleration in the corona and inner heliosphere. ROLSS would be deployed during an early lunar sortie or by a robotic rover as part of an unmanned landing. The prime science mission is to image type II and type III solar radio bursts with the aim of determining the sites at and mechanisms by which the radiating particles are accelerated. Secondary science goals include constraining the density of the lunar ionosphere by searching for a low radio frequency cutoff of the solar radio emissions and constraining the low energy electron population in astrophysical sources. Furthermore, ROLSS serves a pathfinder function for larger lunar radio arrays. Key design requirements on ROLES include the operational frequency and angular resolution. The electron densities in the solar corona and inner heliosphere are such that the relevant emission occurs below 10 MHz, essentially unobservable from Earth's surface due to the terrestrial ionospheric cutoff. Resolving the potential sites of particle acceleration requires an instrument with an angular resolution of at least 2 deg, equivalent to a linear array size of approximately 500 meters. Operations would consist of data acquisition during the lunar day, with regular data downlinks. The major components of the ROLSS array are 3 antenna arms arranged in a Y shape, with a central electronics package (CEP). Each antenna arm is a linear strip of polyimide film (e.g., Kapton (TM)) on which 16 single polarization dipole antennas are located by depositing a conductor (e.g., silver). The arms also contain transmission lines for carrying the radio signals from the science antennas to the CEP.

The use of ultrasound in the study of articulatory properties of vowels in clear speech.

PubMed

Song, Jae Yung

2017-01-01

Although the acoustic properties of clear speech have been extensively studied, its underlying articulatory details have not been well understood. The purpose of the present study is twofold: To examine the specific articulatory processes of clear speech using ultrasound and to investigate whether and how the type of listener (hard of hearing, normal hearing) and the lexical property of words (frequency) interact in the production of clear speech. To this end, we examined productions of /ɑ/, /æ/ and /u/ from 16 speakers of US English. Overall, our ultrasound results suggested that the tongue's highest point moved in a direction that exaggerated the three vowels' phonological features, resulting in an expanded articulatory vowel space for the hard-of-hearing listener and low-frequency words. No interaction was found between the listener and word frequency, suggesting that the effects of word frequency hold constant across the two types of listeners.

Ionospheric Caustics in Solar Radio Observations

NASA Astrophysics Data System (ADS)

Koval, A.; Chen, Y.; Stanislavsky, A.

2016-12-01

The Earth ionosphere possesses by natural focusing and defocusing effects on radio waves due to presence of variable ionospheric irregularities which could act like convergent and divergent lenses on incident radiation. In particular, the focusing of emission from the Sun was firstly detected on the Nançay Decameter Array dynamic spectra in the 1980s. On time-frequency spectrograms the intensity variations form specific structures different from well-known solar radio bursts and clearly distinguishing on a background of solar radiation. Such structures have been identified as ionospheric caustics (ICs) and considered to be the result of radio waves refraction on medium scale travelling ionospheric disturbances (MSTIDs). Although nowadays the ICs are registered by different radio observatories due to augmentation of low-frequency radio telescopes, the most recent papers devoted to ICs in solar radio records date back to the 1980s. In this study, we revisit the ICs issue with some new results by conducting a statistical analysis of occurrence rate of ICs in solar dynamic spectra in meter-decameter wavelength range for long continuous period (15 years). The seasonal variations in ICs appearance have been found for the first time. Besides, we report the possible solar cycle dependence of ICs emergence. The radio waves propagation in the ionosphere comprising MSTIDs will be considered. The present research renews the subject of ICs in the low-frequency solar radio astronomy after about 35-year letup.

On the production mechanism of radio-pulses from large extensive air showers

NASA Technical Reports Server (NTRS)

Datta, P.; Pathak, K. M.

1985-01-01

None of the theories put forward so far to explain the radio emission from cosmic ray showers, has been successful in giving a satisfactory explanation for all the experimental data obtained from various laboratories over the globe. It is apprehended that emission mechanism at low and high frequencies may be quite different. This calls for new theoretical look into the phenomenon. Theoretical as well as the experimental results indicate that the frequency spectrum is rather flat in the frequency range (40 to 60 MHz. Above 80 MHz, the radio emission can be explained with the help of geomagnetic mechanism. But at very low frequency ( 10 MHz), mechanisms other than geomagnetic are involved.

Complex Signal Kurtosis and Independent Component Analysis for Wideband Radio Frequency Interference Detection

NASA Technical Reports Server (NTRS)

Schoenwald, Adam; Mohammed, Priscilla; Bradley, Damon; Piepmeier, Jeffrey; Wong, Englin; Gholian, Armen

2016-01-01

Radio-frequency interference (RFI) has negatively implicated scientific measurements across a wide variation passive remote sensing satellites. This has been observed in the L-band radiometers SMOS, Aquarius and more recently, SMAP [1, 2]. RFI has also been observed at higher frequencies such as K band [3]. Improvements in technology have allowed wider bandwidth digital back ends for passive microwave radiometry. A complex signal kurtosis radio frequency interference detector was developed to help identify corrupted measurements [4]. This work explores the use of ICA (Independent Component Analysis) as a blind source separation technique to pre-process radiometric signals for use with the previously developed real and complex signal kurtosis detectors.

Characterization of a commercial software defined radio as high frequency lock-in amplifier for FM spectroscopy.

PubMed

Mahnke, Peter

2018-01-01

A commercial software defined radio based on a Rafael Micro R820T2 tuner is characterized for the use as a high-frequency lock-in amplifier for frequency modulation spectroscopy. The sensitivity limit of the receiver is 1.6 nV/Hz. Frequency modulation spectroscopy is demonstrated on the 6406.69 cm -1 absorption line of carbon monoxide.

Characterization of a commercial software defined radio as high frequency lock-in amplifier for FM spectroscopy

NASA Astrophysics Data System (ADS)

Mahnke, Peter

2018-01-01

A commercial software defined radio based on a Rafael Micro R820T2 tuner is characterized for the use as a high-frequency lock-in amplifier for frequency modulation spectroscopy. The sensitivity limit of the receiver is 1.6 nV/√{Hz }. Frequency modulation spectroscopy is demonstrated on the 6406.69 cm-1 absorption line of carbon monoxide.

MIT Lincoln Laboratory Facts 2013

DTIC Science & Technology

2012-12-01

efforts span all network layers (from physical to application), with primary focuses on radio - frequency (RF) military satellite communications (MILSATCOM...upgrade, Kwajalein Atoll ■■ Extremely high- frequency submarine communications demonstrated ■■ Lincoln Experimental Satellites 8 and 9 Overview 5...Immersive Surveillance ■■ Lincoln Adaptable Real-time Information Assurance Testbed ■■ Graph detection algorithms ■■ Miniaturized radio - frequency