Sample records for ultraviolet radiation immunosuppression

  1. ULTRAVIOLET RADIATION DOWN-REGULATES ALLERGY IN BALB/C MICE

    EPA Science Inventory

    ULTRAVIOLET RADIATION SUPPRESSES ALLERGY IN BALB/C MICE
    Marsha D.W. Ward+ *, Denise M. Sailstad+, Debora L. Andrews, Elizabeth H. Boykin, and MaryJane K. Selgrade

    ABSTRACT
    The immunosuppressive effects of exposure to ultraviolet radiation (UVR) are well known and the...

  2. PHOTOIMMUNOLOGY

    PubMed Central

    Elmets, Craig A.; Calla, Cather; Xu, Hui

    2014-01-01

    SYNOPSIS The discipline that investigates the biological effects of ultraviolet radiation on the immune system is called photoimmunology. Photoimmunology evolved from an interest in understanding the role of the immune system in skin cancer development, and why immunosuppressed organ transplant recipients are at greatly increased risk for cutaneous neoplasms. Ultraviolet radiation-induced damage DNA modifies the antigen presenting function of cutaneous dendritic cells, biases the immune response towards the generation of regulatory T-cells and stimulates epidermal keratinocyte production of immunosuppressive cytokines. In addition to contributing to an understanding of the pathogenesis of non-melanoma skin cancer, the knowledge acquired about the immunological effects of ultraviolet radiation exposure has provided an understanding of its role in the pathogenesis of other photodermatologic diseases such as polymorphous light eruption, chronic actinic dermatitis and cutaneous lupus erythematosus. This information has also been helpful in developing more effective and safer phototherapeutic devices for the treatment of a variety of cutaneous diseases. PMID:24891051

  3. Resistance of a lizard (the green anole, Anolis carolinensis; Polychridae) to ultraviolet radiation-induced immunosuppression

    USGS Publications Warehouse

    Cope, R.B.; Fabacher, D.L.; Lieske, C.; Miller, C.A.

    2001-01-01

    The green anole (Anolis carolinensis) is the most northerly distributed of its Neotropical genus. This lizard avoids a winter hibernation phase by the use of sun basking behaviors. Inevitably, this species is exposed to high doses of ambient solar ultraviolet radiation (UVR). Increases in terrestrial ultraviolet-B (UV-B) radiation secondary to stratospheric ozone depletion and habitat perturbation potentially place this species at risk of UVR-induced immunosuppression. Daily exposure to subinflammatory UVR (8 kJ/m2/day UV-B, 85 kJ/m2/day ultraviolet A [UV-A]), 6 days per week for 4 weeks (total cumulative doses of 192 kJ/m2 UV-B, 2.04 × 103 kJ/m2 UV-A) did not suppress the anole's acute or delayed type hypersensitivity (DTH) response to horseshoe crab hemocyanin. In comparison with the available literature UV-B doses as low as 0.1 and 15.9 kJ/m2 induced suppression of DTH responses in mice and humans, respectively. Exposure of anoles to UVR did not result in the inhibition of ex vivo splenocyte phagocytosis of fluorescein labeled Escherichia coli or ex vivo splenocyte nitric oxide production. Doses of UV-B ranging from 0.35 to 45 kJ/m2 have been reported to suppress murine splenic/peritoneal macrophage phagocytosis and nitric oxide production. These preliminary studies demonstrate the resistance of green anoles to UVR-induced immunosuppression. Methanol extracts of anole skin contained two peaks in the ultraviolet wavelength range that could be indicative of photoprotective substances. However, the resistance of green anoles to UVR is probably not completely attributable to absorption by UVR photoprotective substances in the skin but more likely results from a combination of other factors including absorption by the cutis and absorption and reflectance by various components of the dermis.

  4. Epidemiology of non-keratinocytic skin cancers among persons with acquired immunodeficiency syndrome in the U.S.

    PubMed Central

    Lanoy, Emilie; Dores, Graça M.; Madeleine, Margaret M.; Toro, Jorge R.; Fraumeni, Joseph F.; Engels, Eric A.

    2009-01-01

    Objective Immunosuppression may increase risk for some skin cancers. We evaluated skin cancer epidemiology among persons with acquired immunodeficiency syndrome (AIDS). Design We linked data from population-based U.S. AIDS and cancer registries to evaluate risk of non-keratinocytic skin cancers (melanoma, Merkel cell carcinoma, and appendageal carcinomas, including sebaceous carcinoma) in 497,142 persons with AIDS. Methods Standardized incidence ratios (SIRs) were calculated to relate skin cancer risk to that in the general population. We used logistic regression to compare risk according to demographic factors, CD4 count, and a geographic index of ultraviolet radiation exposure. Results From 60 months before to 60 months after AIDS onset, persons with AIDS had elevated risks of melanoma (SIR=1.3, 95%CI 1.1-1.4, n=292 cases) and, more strongly, of Merkel cell carcinoma (SIR=11, 95%CI 6.3-17, n=17) and sebaceous carcinoma (SIR=8.1, 95%CI 3.2-17, n=7). Risk for appendageal carcinomas increased with progressive time relative to AIDS onset (p-trend=0.03). Risk of these skin cancers was higher in non-Hispanic whites than other racial/ethnic groups, and melanoma risk was highest among men who have sex with men. Melanoma risk was unrelated to CD4 count at AIDS onset (p=0.32). Risks for melanoma and appendageal carcinomas rose with increasing ultraviolet radiation exposure (p-trend<10-4 and p-trend=10-3, respectively). Conclusions Among persons with AIDS, there is a modest excess risk of melanoma which is not strongly related to immunosuppression and may relate to ultraviolet radiation exposure. In contrast, the greatly increased risks for Merkel cell and sebaceous carcinoma suggest an etiologic role for immunosuppression. PMID:19114864

  5. High azathioprine dose and lip cancer risk in liver, heart, and lung transplant recipients: A population-based cohort study.

    PubMed

    Na, Renhua; Laaksonen, Maarit A; Grulich, Andrew E; Meagher, Nicola S; McCaughan, Geoffrey W; Keogh, Anne M; Vajdic, Claire M

    2016-06-01

    Iatrogenic immunosuppression is a risk factor for lip cancer but the determinants are unknown. We sought to quantify the association between the type, dose, and duration of iatrogenic immunosuppression and lip cancer risk in solid organ transplant recipients. We conducted a population-based cohort study of all adult Australian liver, heart, and lung transplant recipients from 1984 to 2006 (n = 4141). We abstracted longitudinal data from medical records and ascertained incident lip cancer (n = 58) and deaths (n = 1434) by linkage with national registries. We estimated multivariable hazard ratios (HR) for lip cancer using the Fine and Gray proportional subdistribution hazards model, accounting for death as a competing risk. Lip cancer risk (n = 58) increased with high mean daily dose of azathioprine (HR 2.28, 95% confidence interval [CI] 1.18-4.38), longer duration of immunosuppression (HR 9.86, 95% CI 2.10-46.3), increasing year of age at transplantation (HR 1.14, 95% CI 1.04-1.25), earlier transplantation era (HR 8.73, 95% CI 1.11-68.7), and history of smoking (HR 2.71, 95% CI 1.09-6.70). Data on potential confounders such as personal solar ultraviolet radiation exposure were not available. Higher doses of azathioprine increase lip cancer risk, with implications for managing immunosuppressed populations and our understanding of the relationship between solar ultraviolet radiation and lip cancer. Copyright © 2016 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

  6. Ultraviolet-B radiation induces modulation of antigen presentation of herpes simplex virus by human epidermal cells.

    PubMed

    van der Molen, R G; Out-Luiting, C; Claas, F H; Norval, M; Koerten, H K; Mommaas, A M

    2001-06-01

    Although ultraviolet (UV) B radiation is known to be immunosuppressive, there is little information regarding a relevant immunological endpoint to assess human subjects in vivo. Therefore, we have examined the effect of in vivo UV radiation on the ability of human epidermal cells (EC) to present herpes simplex virus (HSV) antigens to memory T cells. Human volunteers, who were seropositive for HSV, were exposed to one minimal erythemal dose (MED) for four consecutive days. EC, prepared from suction blister roofs, were co-cultured with autologous T cells in the presence of HSV. HSV antigen presentation by UV-exposed EC was increased compared with control, nonexposed EC. This up-regulation correlated with an influx of macrophages into the epidermis, which are considered to be associated with UV-induced tolerance. Altering the UV protocol to a sub-erythemal UV dose for four consecutive days or to a single high dose of 2 MED, resulted in suppressed HSV antigen presentation, without the influx of the UV-macrophages. One of the goals of the present study was to eventually use this HSV system to investigate sunscreen immunoprotection. A pilot study with a TiO2-containing sunscreen suggested that the endpoint for UV-induced immunosuppression presented here is promising to be used for human in vivo sunscreen immunoprotection studies.

  7. Mouth cancer in inflammatory bowel diseases.

    PubMed

    Giagkou, E; Christodoulou, D K; Katsanos, K H

    2016-05-01

    Mouth cancer is a major health problem. Multiple risk factors for developing mouth cancer have been studied and include history of tobacco and alcohol abuse, age over 40, exposure to ultraviolet radiation, human papilloma virus infection (HPV), nutritional deficiencies, chronic irritation, and existence or oral potentially malignant lesions such as leukoplakia and lichen planus. An important risk factor for mouth cancer is chronic immunosuppression and has been extensively reported after solid organ transplantation as well as HIV-infected patients. Diagnosis of inflammatory bowel disease (IBD) is not yet considered as a risk factor for oral cancer development. However, a significant number of patients with IBD are receiving immunosuppressants and biological therapies which could represent potential oral oncogenic factors either by direct oncogenic effect or by continuous immunosuppression favoring carcinogenesis, especially in patients with HPV(+) IBD. Education on modifiable risk behaviors in patients with IBD is the cornerstone of prevention of mouth cancer. Oral screening should be performed for all patients with IBD, especially those who are about to start an immunosuppressant or a biologic. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  8. Understanding the connection between platelet-activating factor, a UV-induced lipid mediator of inflammation, immune suppression and skin cancer

    PubMed Central

    Damiani, Elisabetta; Ullrich, Stephen E.

    2016-01-01

    Lipid mediators of inflammation play important roles in several diseases including skin cancer, the most prevalent type of cancer found in the industrialized world. Ultraviolet (UV) radiation is a complete carcinogen and is the primary cause of skin cancer. UV radiation is also a potent immunosuppressive agent, and UV-induced immunosuppression is a well-known risk factor for skin cancer induction. An essential mediator in this process is the glyercophosphocholine 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine commonly referred to as platelet-activating factor (PAF). PAF is produced by keratinocytes in response to diverse stimuli and exerts its biological effects by binding to a single specific G-protein-coupled receptor (PAF-R) expressed on a variety of cells. This review will attempt to describe how this lipid mediator is involved in transmitting the immunosuppressive signal from the skin to the immune system, starting from its production by keratinocytes, to its role in activating mast cell migration in vivo, and to the mechanisms involved that ultimately lead to immune suppression. Recent findings related to its role in regulating DNA repair and activating epigenetic mechanisms, further pinpoint the importance of this bioactive lipid, which may serve as a critical molecular mediator that links the environment (UVB radiation) to the immune system and the epigenome. PMID:27073146

  9. Understanding the connection between platelet-activating factor, a UV-induced lipid mediator of inflammation, immune suppression and skin cancer.

    PubMed

    Damiani, Elisabetta; Ullrich, Stephen E

    2016-07-01

    Lipid mediators of inflammation play important roles in several diseases including skin cancer, the most prevalent type of cancer found in the industrialized world. Ultraviolet (UV) radiation is a complete carcinogen and is the primary cause of skin cancer. UV radiation is also a potent immunosuppressive agent, and UV-induced immunosuppression is a well-known risk factor for skin cancer induction. An essential mediator in this process is the glyercophosphocholine 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine commonly referred to as platelet-activating factor (PAF). PAF is produced by keratinocytes in response to diverse stimuli and exerts its biological effects by binding to a single specific G-protein-coupled receptor (PAF-R) expressed on a variety of cells. This review will attempt to describe how this lipid mediator is involved in transmitting the immunosuppressive signal from the skin to the immune system, starting from its production by keratinocytes, to its role in activating mast cell migration in vivo, and to the mechanisms involved that ultimately lead to immune suppression. Recent findings related to its role in regulating DNA repair and activating epigenetic mechanisms, further pinpoint the importance of this bioactive lipid, which may serve as a critical molecular mediator that links the environment (UVB radiation) to the immune system and the epigenome. Copyright © 2016 Elsevier B.V. All rights reserved.

  10. A single sub-erythematous exposure of solar-simulated radiation on the elicitation phase of contact hypersensitivity induces IL-10-producing T-regulatory cells in human skin.

    PubMed

    Stoebner, Pierre E; Rahmoun, Massilva; Ferrand, Christophe; Meunier, Laurent; Yssel, Hans; Pène, Jérôme

    2006-08-01

    Solar ultraviolet (UV) radiation has hazardous effects on human health that are, in part, associated with its immunosuppressive effects via the induction of interleukin (IL)-10 production. Although IL-10 is produced by both T helper type 2 (Th2) cells and T-regulatory type 1 (Tr1) cells, the relative contribution of either subset in UV radiation-induced immunosuppression has not been established. Here, we show that T cells isolated from non-treated allergic contact dermatitis (ACD) reactions, 48 h following nickel challenge and propagated for 7-10 days in the presence of IL-2, were mainly CD4(+) and produced IL-10, but little interferon-gamma. A single sub-erythematous solar-simulated radiation (SSR) prior to antigen challenge exposure resulted in a clinical attenuation of the intensity of ACD reactions which was associated with a significant increase in both the magnitude of IL-10 production by skin-infiltrating T cells and the frequency of IL-10-producing Tr1 cells. Skin-infiltrating T cells in SSR-exposed, as well as non-exposed, ACD reactions showed a perturbed T-cell receptor (TCR)-Vbeta repertoire, without overexpression of a particular TCR-Vbeta gene product, indicating the presence of high frequencies of nickel non-specific T cells in ACD reactions. These results show that a single sub-erythematous SSR induces immunosuppression via the cutaneous infiltration of IL-10-producing Tr1, and to a lesser extent, Th2 cells.

  11. Solar ultraviolet radiation, vitamin D and skin cancer surveillance in organ transplant recipients (OTRs): an update.

    PubMed

    Reichrath, Jörg

    2014-01-01

    During the last decades, the annual numbers of performed solid organ transplants have continuously increased world-wide. Solid organ transplant recipients (OTR) have a greater risk to develop malignancies, with skin cancer representing the most common neoplasia. Additionally, OTRs in general develop a more aggressive form of malignancies. In consequence, dermatologic surveillance is of high importance for OTRs and these patients represent an increasing and significant challenge to clinicians including dermatologists. In OTRs, patient and organ survival have increased considerably and continuously over the past two decades as a result of better immunosuppressive regimens and better posttransplant care. Great progress has been made in our understanding that individual immunosuppressive regiments differ in their effect on skin cancer risk in OTRs, and that effects of individual immunosuppressive regiments on skin cancer risk depend on various other factors including viral infections. Since sunlight is the major source of vitamin D for most humans, OTRs, who have to protect themselves consequently against solar or artificial UV radiation, are at high risk of developing vitamin D deficiency. Vitamin D deficiency is not only associated with increased risk for metabolic bone disease, but with other severe health problems including various types of malignancies. As a consequence, screening for and treatment of vitamin D deficiency is warranted in OTRs. In this review, we give an update on our present understanding of skin cancer surveillance in OTRs.

  12. Role of Ultraviolet Radiation in Papillomavirus-Induced Disease

    PubMed Central

    Uberoi, Aayushi; Yoshida, Satoshi; Frazer, Ian H.; Pitot, Henry C.; Lambert, Paul F.

    2016-01-01

    Human papillomaviruses are causally associated with 5% of human cancers. The recent discovery of a papillomavirus (MmuPV1) that infects laboratory mice provides unique opportunities to study the life cycle and pathogenesis of papillomaviruses in the context of a genetically manipulatable host organism. To date, MmuPV1-induced disease has been found largely to be restricted to severely immunodeficient strains of mice. In this study, we report that ultraviolet radiation (UVR), specifically UVB spectra, causes wild-type strains of mice to become highly susceptible to MmuPV1-induced disease. MmuPV1-infected mice treated with UVB develop warts that progress to squamous cell carcinoma. Our studies further indicate that UVB induces systemic immunosuppression in mice that correlates with susceptibility to MmuPV1-associated disease. These findings provide new insight into how MmuPV1 can be used to study the life cycle of papillomaviruses and their role in carcinogenesis, the role of host immunity in controlling papillomavirus-associated pathogenesis, and a basis for understanding in part the role of UVR in promoting HPV infection in humans. PMID:27244228

  13. Role of Ultraviolet Radiation in Papillomavirus-Induced Disease.

    PubMed

    Uberoi, Aayushi; Yoshida, Satoshi; Frazer, Ian H; Pitot, Henry C; Lambert, Paul F

    2016-05-01

    Human papillomaviruses are causally associated with 5% of human cancers. The recent discovery of a papillomavirus (MmuPV1) that infects laboratory mice provides unique opportunities to study the life cycle and pathogenesis of papillomaviruses in the context of a genetically manipulatable host organism. To date, MmuPV1-induced disease has been found largely to be restricted to severely immunodeficient strains of mice. In this study, we report that ultraviolet radiation (UVR), specifically UVB spectra, causes wild-type strains of mice to become highly susceptible to MmuPV1-induced disease. MmuPV1-infected mice treated with UVB develop warts that progress to squamous cell carcinoma. Our studies further indicate that UVB induces systemic immunosuppression in mice that correlates with susceptibility to MmuPV1-associated disease. These findings provide new insight into how MmuPV1 can be used to study the life cycle of papillomaviruses and their role in carcinogenesis, the role of host immunity in controlling papillomavirus-associated pathogenesis, and a basis for understanding in part the role of UVR in promoting HPV infection in humans.

  14. An essential role for platelet-activating factor in activating mast cell migration following ultraviolet irradiation

    PubMed Central

    Chacón-Salinas, Rommel; Chen, Limo; Chávez-Blanco, Alma D.; Limón-Flores, Alberto Y.; Ma, Ying; Ullrich, Stephen E.

    2014-01-01

    The UVB (290–320 nm) radiation in sunlight is responsible for inducing skin cancer. Exposure to UV radiation is also immunosuppressive, and the systemic immune suppression induced by UV is a well-recognized risk factor for cancer induction. As UVB radiation is absorbed within the upper layers of the skin, indirect mechanisms must play a role in activating systemic immune suppression. One prominent example is mast cell migration, which from the skin to the draining LN is an essential step in the cascade of events leading to immune suppression. What triggers mast cell migration is not entirely clear. Here, we tested the hypothesis that PAF, a lipid mediator of inflammation produced by the skin in response to UV exposure, is involved. Mast cell-deficient mice (KitW-sh/W-sh) are resistant to the suppressive effect of UV radiation, and reconstituting mast cell-deficient mice with normal bone marrow-derived mast cells restores susceptibility to immunosuppression. However, when mast cells from PAFR−/− mice were used, the reconstituted mice were not susceptible to the suppressive effects of UV. Furthermore, PAFR−/− mice showed impaired UV-induced mast cell migration when compared with WT mice. Finally, injecting PAF into WT mice mimicked the effect of UV irradiation and induced mast cell migration but not in PAFR−/− mice. Our findings indicate that PAFR binding induces mast cells to migrate from the skin to the LNs, where they mediate immune suppression. PMID:24009177

  15. Effect of ultraviolet irradiation on free radical scavenging activity of immunosuppressants used in lung transplantation and comparative electron paramagnetic resonance study of kinetics of their interactions with model free radicals.

    PubMed

    Stanjek-Cichoracka, A; Żegleń, S; Ramos, P; Pilawa, B; Wojarski, J

    2018-06-01

    The immunosuppressive drugs used in solid organ transplantation or autoimmunological processes were studied by electron paramagnetic resonance (EPR) spectroscopy to estimate their free radical scavenging activity. The interactions of immunosuppressants with free radicals were examined by an X-band (9.3 GHz) EPR spectroscopy and a model of DPPH free radicals. The EPR spectra of DPPH and DPPH interacting with individual drugs were compared. Kinetic studies were performed, and the effect of ultraviolet (UV) irradiation on the free radical scavenging activity of the tested drugs was determined. The free radical scavenging activity of non-irradiated drugs decreased in the order: rapamycin > mycophenolate mofetil > ciclosporin > tacrolimus. UV irradiation increased the free radical scavenging activity of all the tested immunosuppressive drugs, and the effect was highest for tacrolimus. For the non-irradiated samples, the speed of free radical interactions decreased in the order: ciclosporin > tacrolimus > mycophenolate mofetil > rapamycin. UV irradiation only slightly affected the speed of interactions of the immunosuppressive drugs with the model DPPH free radicals. Electron paramagnetic resonance spectroscopy is useful for obtaining information on interactions of immunosuppressive drugs with free radicals. We hypothesized that the long-term immunosuppressive effects of these drugs after transplantation or during autoimmune disorders may be mediated by anti-inflammatory action in addition to the known receptor/cell cycle inhibition. © 2018 John Wiley & Sons Ltd.

  16. Sunlight Effects on Immune System: Is There Something Else in addition to UV-Induced Immunosuppression?

    PubMed Central

    Paz, M. L.; Leoni, J.

    2016-01-01

    Sunlight, composed of different types of radiation, including ultraviolet wavelengths, is an essential source of light and warmth for life on earth but has strong negative effects on human health, such as promoting the malignant transformation of skin cells and suppressing the ability of the human immune system to efficiently detect and attack malignant cells. UV-induced immunosuppression has been extensively studied since it was first described by Dr. Kripke and Dr. Fisher in the late 1970s. However, skin exposure to sunlight has not only this and other unfavorable effects, for example, mutagenesis and carcinogenesis, but also a positive one: the induction of Vitamin D synthesis, which performs several roles within the immune system in addition to favoring bone homeostasis. The impact of low levels of UV exposure on the immune system has not been fully reported yet, but it bears interesting differences with the suppressive effect of high levels of UV radiation, as shown by some recent studies. The aim of this article is to put some ideas in perspective and pose some questions within the field of photoimmunology based on established and new information, which may lead to new experimental approaches and, eventually, to a better understanding of the effects of sunlight on the human immune system. PMID:28070504

  17. Reactive oxygen-mediated damage to a human DNA replication and repair protein.

    PubMed

    Montaner, Beatriz; O'Donovan, Peter; Reelfs, Olivier; Perrett, Conal M; Zhang, Xiaohong; Xu, Yao-Zhong; Ren, Xiaolin; Macpherson, Peter; Frith, David; Karran, Peter

    2007-11-01

    Ultraviolet A (UVA) makes up more than 90% of incident terrestrial ultraviolet radiation. Unlike shorter wavelength UVB, which damages DNA directly, UVA is absorbed poorly by DNA and is therefore considered to be less hazardous. Organ transplant patients treated with the immunosuppressant azathioprine frequently develop skin cancer. Their DNA contains 6-thioguanine-a base analogue that generates DNA-damaging singlet oxygen ((1)O(2)) when exposed to UVA. Here, we show that this (1)O(2) damages proliferating cell nuclear antigen (PCNA), the homotrimeric DNA polymerase sliding clamp. It causes covalent oxidative crosslinking between the PCNA subunits through a histidine residue in the intersubunit domain. Crosslinking also occurs after treatment with higher-although still moderate-doses of UVA alone or with chemical oxidants. Chronic accumulation of oxidized proteins is linked to neurodegenerative disorders and ageing. Our findings identify oxidative damage to an important DNA replication and repair protein as a previously unrecognized hazard of acute oxidative stress.

  18. Dietary eicosapentaenoic acid prevents systemic immunosuppression in mice induced by UVB radiation.

    PubMed

    Moison, R M; Beijersbergen Van Henegouwen, G M

    2001-07-01

    Moison, R. M. W. and Beijersbergen van Henegouwen, G. M. J. Dietary Eicosapentaenoic Acid Prevents Systemic Immunosuppression in Mice Induced by UVB Radiation. Radiat. Res. 156, 36-44 (2001). Reactive oxygen species (ROS) contribute to the immunosuppression induced by UVB radiation. Omega-3 fatty acids in fish oil, e.g. eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), can modulate immunoresponsiveness, but because of their susceptibility to ROS-induced damage, they can also challenge the epidermal antioxidant defense system. The influence of dietary supplementation with different omega-3 fatty acids on systemic immunosuppression induced in mice by UVB radiation was studied using the contact hypersensitivity response to trinitrochlorobenzene. In an attempt to study the mechanisms involved, UVB-radiation-induced changes in epidermal antioxidant status were also studied. Mice received high-fat (25% w/w) diets enriched with either oleic acid (control diet), EPA, DHA, or EPA + DHA (MaxEPA). Immunosuppression induced by UVB radiation was 53% in mice fed the oleic acid diet and 69% in mice fed the DHA diet. In contrast, immunosuppression was only 4% and 24% in mice fed the EPA and MaxEPA diets, respectively. Increased lipid peroxidation and decreased vitamin E levels (P < 0.05) were found in unirradiated mice fed the MaxEPA and DHA diets. For all diets, exposure to UVB radiation increased lipid peroxidation (P < 0.05), but levels of glutathione (P < 0.05) and vitamin C (P > 0.05) decreased only in the mice given fish oil. UVB irradiation did not influence vitamin E levels. In conclusion, dietary EPA, but not DHA, protects against UVB-radiation-induced immunosuppression in mice. The degree of protection appears to be related to the amount of EPA incorporated and the ability of the epidermis to maintain an adequate antioxidant level after irradiation.

  19. Vitamin D and solar ultraviolet radiation in the risk and treatment of tuberculosis.

    PubMed

    Ralph, Anna P; Ralph, Anna R; Lucas, Robyn M; Norval, Mary

    2013-01-01

    Improved understanding of the association between tuberculosis and vitamin D is needed to inform clinical practice. Vitamin D has both immunostimulatory and immunosuppressive effects relevant to human antimycobacterial responses. Ultraviolet radiation, the main source of vitamin D, also induces immunomodulation and could affect the relation between vitamin D and tuberculosis. Clinical trials of vitamin D supplementation in patients with tuberculosis have produced largely negative results, prompting the review of dosing regimens-an explanation for low 25-hydroxyvitamin D status in patients with active tuberculosis is also needed. The reporting of vitamin D deficiency needs to address assay inaccuracies, rising thresholds to define sufficiency, and scarce knowledge of the concentrations needed for optimum immune responses. Future research to measure the effect of the inflammatory setting on serum concentrations of 25-hydroxyvitamin D, at tuberculosis diagnosis and during recovery, could help to account for 25-hydroxyvitamin D changes in these concentrations in patients with tuberculosis. Studies into the role of vitamin D supplementation in latent tuberculosis justify clinical trials in this population, but pose methodological challenges. Vitamin D trials in patients with active tuberculosis should be done in well selected populations using adequate vitamin D doses, although such doses remain undefined. Copyright © 2013 Elsevier Ltd. All rights reserved.

  20. MicroRNAs in Skin Response to UV Radiation

    PubMed Central

    Syed, Deeba N.; Khan, Mohammad Imran; Shabbir, Maria; Mukhtar, Hasan

    2014-01-01

    Solar ultraviolet (UV) radiation, an ubiquitous environmental carcinogen, is classified depending on the wave-length, into three regions; short-wave UVC (200–280 nm), mid-wave UVB (280–320 nm), and long-wave UVA (320–400 nm). The human skin, constantly exposed to UV radiation, particularly the UVB and UVA components, is vulnerable to its various deleterious effects such as erythema, photoaging, immunosuppression and cancer. To counteract these and for the maintenance of genomic integrity, cells have developed several protective mechanisms including DNA repair, cell-cycle arrest and apoptosis. The network of damage sensors, signal transducers, mediators, and various effector proteins is regulated through changes in gene expression. MicroRNAs (miRNAs), a group of small non-coding RNAs, act as post-transcriptional regulators through binding to complementary sequences in the 3′-untranslated region of their target genes, resulting in either translational repression or target degradation. Recent studies show that miRNAs add an additional layer of complexity to the intricately controlled cellular responses to UV radiation. This review summarizes our current knowledge of the role of miRNAs in the regulation of the human skin response upon exposure to UV radiation. PMID:23834148

  1. Merkel cell carcinoma in an immunosuppressed patient.

    PubMed

    Góes, Heliana Freitas de Oliveira; Lima, Caren Dos Santos; Issa, Maria Cláudia de Almeida; Luz, Flávio Barbosa; Pantaleão, Luciana; Paixão, José Gabriel Miranda da

    2017-01-01

    Merkel cell carcinoma is an uncommon neuroendocrine carcinoma with a rising incidence and an aggressive behavior. It predominantly occurs in older patients, with onset occurring at a mean age of 75-80 years. Recognized risk factors are ultraviolet sunlight exposure, immunosuppression, and, more recently, Merkel cell polyomavirus. We report a case of Merkel cell carcinoma in a young HIV positive patient with Merkel Cell polyomavirus detected in the tumor.

  2. Silymarin inhibits ultraviolet radiation-induced immune suppression through DNA repair-dependent activation of dendritic cells and stimulation of effector T cells

    PubMed Central

    Vaid, Mudit; Prasad, Ram; Singh, Tripti; Elmets, Craig A.; Xu, Hui; Katiyar, Santosh K.

    2013-01-01

    Silymarin inhibits UVB-induced immunosuppression in mouse skin. To identify the molecular mechanisms underlying this effect, we used an adoptive transfer approach in which dendritic cells (DCs) from the draining lymph nodes of donor mice that had been UVB-exposed and sensitized to 2,4,-dinitrofluorobenzene (DNFB) were transferred into naïve recipient mice. The contact hypersensitivity (CHS) response of the recipient mice to DNFB was then measured. When DCs were obtained from UVB-exposed donor mice that were not treated with silymarin, the CHS response was suppressed confirming the role of DCs in the UVB-induced immunosuppression. Silymarin treatment of UVB-exposed donor mice relieved this suppression of the CHS response in the recipients. Silymarin treatment was associated with rapid repair of UVB-induced cyclobutane pyrimidine dimers (CPDs) in DCs and silymarin treatment did not prevent UV-induced immunosuppression in XPA-deficient mice which are unable to repair UV-induced DNA damage. The CHS response in mice receiving DCs from silymarin-treated UV-exposed donor mice also was associated with enhanced secretion of Th1-type cytokines and stimulation of T cells. Adoptive transfer of T cells revealed that transfer of either CD8+ or CD4+ cells from silymarin-treated, UVB-exposed donors resulted in enhancement of the CHS response. Cell culture study showed enhanced secretion of IL-2 and IFNγ by CD8+ T cells, and reduced secretion of Th2 cytokines by CD4+ cells, obtained from silymarin-treated UVB-exposed mice. These data suggest that DNA repair-dependent functional activation of DCs, a reduction in CD4+ regulatory T-cell activity, and stimulation of CD8+ effector T cells contribute to silymarin-mediated inhibition of UVB-induced immunosuppression. PMID:23395695

  3. Ultraviolet-B radiation and the immune response of rainbow trout: Chapter 18

    USGS Publications Warehouse

    Fabacher, David L.; Little, Edward E.; Jones, S.B.; DeFabo, E.C.; Webber, L.J.; Stolen, Joanne S.; Fletcher, Thelma C.

    1994-01-01

    As part of a larger study on global climate change and ozone depletion we are investigating the effects of ultraviolet-B (UVB) radiation on fishes. We conducted a number of experiments to explore the possible effects of UVB radiation on the immune response of juvenile rainbow trout Oncorhynchus mykiss. In one study, the fish developed sunburn and fungal infection on the dorsal skin after exposure to levels of UVB that simulated ambient solar UVB levels observed at mid-latitudes. In a separate study, UVB-exposed rainbow trout with surgically administered dorsal lesions developed fungal infection on the lesions and surrounding skin. Many of these fish subsequently died within a 9 day exposure period. Fish with surgical lesions, but not exposed to UVB radiation, did not develop fungal infection and did not die. In mammals, UVB-induced immunosuppression is thought to occur through the isomerization of urocanic acid or the formation of DNA pyrimidine dimers, or through some interaction between the two. We found a substance that appeared, upon HPLC detection, to be trans-urocanic acid in the skin of UVB-exposed and unexposed rainbow trout. Neurotransmitter stimulation of adrenoceptors may be involved in changes in pigmentation observed in UVB-exposed fishes. We measured adrenoceptors in skin membranes from rainbow trout exposed to UVB and found a decrease in cz2-adrenoceptors compared with fish not exposed to UVB. Results of our study indicate that prolonged exposure of juvenile rainbow trout to mid-latitude levels of solar UVB may play an important role in the initiation of certain disease outbreaks and may decrease survival of fish that have lesions on the dorsal skin.

  4. The alternative complement component factor B regulates UV-induced oedema, systemic suppression of contact and delayed hypersensitivity, and mast cell infiltration into the skin.

    PubMed

    Byrne, Scott N; Hammond, Kirsten J L; Chan, Carling Y-Y; Rogers, Linda J; Beaugie, Clare; Rana, Sabita; Marsh-Wakefield, Felix; Thurman, Joshua M; Halliday, Gary M

    2015-04-01

    Ultraviolet (UV) wavelengths in sunlight are the prime cause of skin cancer in humans with both the UVA and UVB wavebands making a contribution to photocarcinogenesis. UV has many different biological effects on the skin that contribute to carcinogenesis, including suppression of adaptive immunity, sunburn and altering the migration of mast cells into and away from irradiated skin. Many molecular mechanisms have been identified as contributing to skin responses to UV. Recently, using gene set enrichment analysis of microarray data, we identified the alternative complement pathway with a central role for factor B (fB) in UVA-induced immunosuppression. In the current study we used mice genetically deficient in fB (fB-/- mice) to study the functional role of the alternative complement pathway in skin responses to UV. We found that fB is required for not only UVA but also UVB-induced immunosuppression and solar-simulated UV induction of the oedemal component of sunburn. Factor B-/- mice had a larger number of resident skin mast cells than control mice, but unlike the controls did not respond to UV by increasing mast cell infiltration into the skin. This study provides evidence for a function role for fB in skin responses to UV radiation. Factor B regulates UVA and UVB induced immunosuppression, UV induced oedema and mast cell infiltration into the skin. The alternative complement pathway is therefore an important regulator of skin responses to UV.

  5. A review of studies on the effects of ultraviolet irradiation on the resistance to infections: evidence from rodent infection models and verification by experimental and observational human studies.

    PubMed

    Termorshuizen, F; Garssen, J; Norval, M; Koulu, L; Laihia, J; Leino, L; Jansen, C T; De Gruijl, F; Gibbs, N K; De Simone, C; Van Loveren, H

    2002-02-01

    Recent studies on the immunosuppressive effects of ultraviolet radiation (UVR) and the related resistance to infections in rodents and humans are presented. The waveband dependency of trans-to-cis isomerisation of urocanic acid in the stratum corneum and the role of DNA damage in UVR-induced erythema and immunosuppression were investigated to further elucidate the underlying mechanisms. Furthermore, human experimental studies on UVR-induced immunomodulation were performed. It appeared that the doses needed to suppress various immune parameters in humans (e.g. NK activity, contact hypersensitivity) were higher than those needed in experiments in rodents. Still, extrapolation of experimental animal data to the human situation showed that UVR may impair the resistance to different systemic infections at relevant outdoor doses. In observational human studies we aimed to substantiate the relevance of UVR for infections in humans. It was shown that sunny season was associated with a slightly retarded but clinically non-relevant antibody response to hepatitis B vaccination. Furthermore, sunny season appeared to be associated with a small decline in the number of CD4+ T-helper cells in a cohort of HIV-infected persons and a higher recurrence of herpes simplex and herpes zoster in a cohort of renal transplant recipients. However, in a study among young children a higher exposure to solar UVR was associated with a lower occurrence of upper respiratory tract symptoms. As disentangling the effects of UVR from other relevant factors is often impossible in observational studies, concise quantitative risk estimations for the human situation cannot be given at present.

  6. Corona And Ultraviolet Equipment For Testing Materials

    NASA Technical Reports Server (NTRS)

    Laue, Eric G.

    1993-01-01

    Two assemblies of laboratory equipment developed for use in testing abilities of polymers, paints, and other materials to withstand ultraviolet radiation and charged particles. One is vacuum ultraviolet source built around commercial deuterium lamp. Other exposes specimen in partial vacuum to both ultraviolet radiation and brush corona discharge. Either or both assemblies used separately or together to simulate approximately combination of solar radiation and charged particles encountered by materials aboard spacecraft in orbit around Earth. Also used to provide rigorous environmental tests of materials exposed to artificial ultraviolet radiation and charged particles in industrial and scientific settings or to natural ultraviolet radiation and charged particles aboard aircraft at high altitudes.

  7. The influence of UV radiation on protistan evolution

    NASA Technical Reports Server (NTRS)

    Rothschild, L. J.

    1999-01-01

    Ultraviolet radiation has provided an evolutionary challenge to life on Earth. Recent increases in surficial ultraviolet B fluxes have focused attention on the role of UV radiation in protistan ecology, cancer, and DNA damage. Exploiting this new wealth of data, I examine the possibility that ultraviolet radiation may have played a significant role in the evolution of the first eukaryotes, that is, protists. Protists probably arose well before the formation of a significant ozone shield, and thus were probably subjected to substantial ultraviolet A, ultraviolet B, and ultraviolet C fluxes early in their evolution. Evolution consists of the generation of heritable variations and the subsequent selection of these variants. Ultraviolet radiation has played a role both as a mutagen and as a selective agent. In its role as a mutagen, it may have been crucial in the origin of sex and as a driver of molecular evolution. As a selective agent, its influence has been broad. Discussed in this paper are the influence of ultraviolet radiation on biogeography, photosynthesis, and desiccation resistance.

  8. Photoluminescence emission spectra of Makrofol® DE 1-1 upon irradiation with ultraviolet radiation

    NASA Astrophysics Data System (ADS)

    El Ghazaly, M.; Aydarous, Abdulkadir

    Photoluminescence (PL) emission spectra of Makrofol® DE 1-1 (bisphenol-A based polycarbonate) upon irradiation with ultraviolet radiation of different wavelengths were investigated. The absorption-and attenuation coefficient measurements revealed that the Makrofol® DE 1-1 is characterized by high absorbance in the energy range 6.53-4.43 eV but for a lower energy than 4.43 eV, it is approximately transparent. Makrofol® DE 1-1 samples were irradiated with ultraviolet radiation of wavelength in the range from 250 (4.28 eV) to 400 (3.10 eV) nm in step of 10 nm and the corresponding photoluminescence (PL) emission spectra were measured with a spectrofluorometer. It is found that the integrated counts and the peak height of the photoluminescence emission (PL) bands are strongly correlated with the ultraviolet radiation wavelength. They are increased at the ultraviolet radiation wavelength 280 nm and have maximum at 290 nm, thereafter they decrease and diminish at 360 nm of ultraviolet wavelength. The position of the PL emission band peak was red shifted starting from 300 nm, which increased with the increase the ultraviolet radiation wavelength. The PL bandwidth increases linearly with the increase of the ultraviolet radiation wavelength. When Makrofol® DE 1-1 is irradiated with ultraviolet radiation of short wavelength (UVC), the photoluminescence emission spectra peaks also occur in the UVC but of a relatively longer wavelength. The current new findings should be considered carefully when using Makrofol® DE 1-1 in medical applications related to ultraviolet radiation.

  9. Role of Activin A in Immune Responses to Breast Cancer

    DTIC Science & Technology

    2013-12-01

    Demaria. APPENDIX 2 ( PS4 -57) Radiation-induced activin-a fosters tumor-mediated immunosuppression in breast cancer. Claire Vanpouille-Box, Julie...with immunotherapy in the clinic.   APPENDIX 2 ( PS4 -57) Radiation-induced activin-a fosters tumor-mediated immunosuppression in breast cancer...Claire Vanpouille-Box, Julie Diamond, Silvia Formenti and Sandra Demaria. POSTER PRESENTATION – 59th RRS annual Meeting. ( PS4 -57) Radiation-induced

  10. ULTRAVIOLET PROTECTIVE PIGMENTS AND DNA DIMER INDUCTION AS RESPONSES TO ULTRAVIOLET RADIATION

    EPA Science Inventory

    Life on Earth has evolved adaptations to many environmental stresses over the epochs. One consistent stress has been exposure to ultraviolet (UV) radiation. The most basic effect of UV radiation on biological systems is damage to DNA. In response to UV radiation organisms have ad...

  11. Ultraviolet radiation induced discharge laser

    DOEpatents

    Gilson, Verle A.; Schriever, Richard L.; Shearer, James W.

    1978-01-01

    An ultraviolet radiation source associated with a suitable cathode-anode electrode structure, disposed in a gas-filled cavity of a high pressure pulsed laser, such as a transverse electric atmosphere (TEA) laser, to achieve free electron production in the gas by photoelectric interaction between ultraviolet radiation and the cathode prior to the gas-exciting cathode-to-anode electrical discharge, thereby providing volume ionization of the gas. The ultraviolet radiation is produced by a light source or by a spark discharge.

  12. Merkel cell carcinoma: Epidemiology, pathogenesis, diagnosis and therapy.

    PubMed

    Amaral, Teresa; Leiter, Ulrike; Garbe, Claus

    2017-12-01

    Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer with a neuroendocrine phenotype. Incidence varies according to the geographic regions but is overall increasing. Different risk factors have been identified namely advanced age, immunosuppression, and ultraviolet light exposure. An association between MCC and polyomavirus infection is known. However, the exact mechanism that leads to carcinogenesis is yet to be fully understood. Surgery when feasible is the recommended treatment for localized disease, followed by adjuvant radiation or chemoradiation. In the metastatic setting, chemotherapy has been the standard treatment. However, two recently published trials with immune checkpoint inhibitors in first and second line showed promising results with a tolerable safety profile and these might become the standard therapy shortly. Somatostatin receptors are expressed in many MCC but such expression is not associated with disease severity. Presently there are no biomarkers predictive of response that could help to better select patients to these new therapies, and additional research is essential.

  13. Ultraviolet absorption hygrometer

    DOEpatents

    Gersh, M.E.; Bien, F.; Bernstein, L.S.

    1986-12-09

    An ultraviolet absorption hygrometer is provided including a source of pulsed ultraviolet radiation for providing radiation in a first wavelength region where water absorbs significantly and in a second proximate wavelength region where water absorbs weakly. Ultraviolet radiation in the first and second regions which has been transmitted through a sample path of atmosphere is detected. The intensity of the radiation transmitted in each of the first and second regions is compared and from this comparison the amount of water in the sample path is determined. 5 figs.

  14. UVA radiation impairs phenotypic and functional maturation of human dermal dendritic cells.

    PubMed

    Furio, Laetitia; Berthier-Vergnes, Odile; Ducarre, Blandine; Schmitt, Daniel; Peguet-Navarro, Josette

    2005-11-01

    There is now strong evidence that the ultraviolet A (UVA) part of the solar spectrum contributes to the development of skin cancers. Its effect on the skin immune system, however, has not been fully investigated. Here, we analyzed the effects of UVA radiation on dermal dendritic cells (DDC), which, in addition, provided further characterization of these cells. Dermal sheets were obtained from normal human skin and irradiated, or not, with UVA at 2 or 12 J per cm2. After a 2 d incubation, the phenotype of emigrant cells was analyzed by double immunostaining and flow cytometry. Results showed that migratory DDC were best characterized by CD1c expression and that only few cells co-expressed the Langerhans cell marker Langerin. Whereas the DC extracted from the dermis displayed an immature phenotype, emigrant DDC showed increased expression of HLA-DR and acquired co-stimulation and maturation markers. We showed here that UVA significantly decreased the number of viable emigrant DDC, a process related to increased apoptosis. Furthermore, UVA irradiation impaired the phenotypic and functional maturation of migrating DDC into potent antigen-presenting cells, in a concentration-dependent manner. The results provide further evidence that UVA are immunosuppressive and suggest an additional mechanism by which solar radiation impairs immune response.

  15. UVA1 a promising approach for scleroderma

    PubMed Central

    Keyal, Uma; Bhatta, Anil Kumar; Wang, Xiu Li

    2017-01-01

    Scleroderma is a complex connective tissue disease characterized by fibrosis, vasculopathy, and immune system dysfunction. The heterogeneity of disease presentation and poorly understood etiology has made the management of scleroderma difficult. The available treatment options like immunosuppressive agents are associated with potentially hazardous side effects and physiotherapy, which to a certain degree helps to minimize the loss of function in digits and limbs, has only limited success. Also, studies investigating antifibrotic therapies have failed to report any significant improvement. Hence, there is currently no effective therapy for scleroderma. Recently, phototherapy has been extensively studied and found to be effective in treating scleroderma. Initially psoralen + ultraviolet A (PUVA) significantly enriched the therapeutic panel, but more recently ultraviolet A1 (UVA1) is seen to replace PUVA therapy. This might be because of UVA1 therapy being free of side effects seen with psoralens such as nausea, vomiting or photokeratitis. In addition, UVA1 is seen to lower risk of phototoxic reactions with deeper penetration of radiation. The present review will put some light on the use of UVA1 for treating cutaneous lesion in scleroderma and we aim to find the most benefitted group of patients and most effective dose of UVA1 for different types of scleroderma. PMID:28979701

  16. Vacuum and ultraviolet radiation effects on binders and pigments for spacecraft thermal control coatings

    NASA Technical Reports Server (NTRS)

    Progar, D. J.; Wade, W. R.

    1971-01-01

    An evaluation of several silicone resin binders and powdered inorganic pigments for potential use in spacecraft thermal-control paint formulations is presented. The pigments were selected on the basis of a hypothesis relating the heat of formation of a compound to the compound's resistance to ultra-radiation-induced degradation. Reflectance measurements were made in situ to determine degradation rates due to ultraviolet radiation. The tested polydimethylsiloxane resins were not significantly affected by long exposures to ultraviolet radiation. All the pigments, which were dispersed in a polydimethylsiloxane resin, were degraded by ultraviolet radiation as determined by an increase of solar absorptance. For the materials evaluated in this study, no evidence was found to indicate that pigments with high heats of formation were resistant to ultraviolet degradation.

  17. ASSESSMENT OF THE RISK OF SOLAR ULTRAVIOLET RADIATION TO AMPHIBIANS. II: IN SITU CHARACTERIZATION OF SOLAR ULTRAVIOLET RADIATION IN AMPHIBIAN HABITATS

    EPA Science Inventory

    Ultraviolet B (UVB) radiation has been hypothesized as a potential cause of amphibian population declines and increased incidences of malformations. Realistic studies documenting UV irradiance or dose have rarely been conducted in wetlands used by amphibians. We demonstrate that ...

  18. Fluorescence of molecular hydrogen excited by solar extreme-ultraviolet radiation

    NASA Technical Reports Server (NTRS)

    Feldman, P. D.; Fastie, W. G.

    1973-01-01

    During trans-earth coast, the Apollo 17 ultraviolet spectrometer was scheduled to make observations of the far ultraviolet background in selected regions of the sky. In the course of one of these observations, the spacecraft fuel cells were routinely purged of excess hydrogen and water vapor. The ultraviolet fluorescence spectrum of the purged molecular hydrogen excited by solar extreme ultraviolet radiation is interpreted by absorption of solar L-beta and L-gamma radiation in the nearly resonant (6, 0) and (11, 0) Lyman bands. The results are deemed significant for ultraviolet spectroscopic investigations of the atmospheres of the moon and planets since Lyman-band fluorescence provides an unambiguous means of identification of molecular hydrogen in upper atmospheres.

  19. Flame detector operable in presence of proton radiation

    NASA Technical Reports Server (NTRS)

    Walker, D. J.; Turnage, J. E.; Linford, R. M. F.; Cornish, S. D. (Inventor)

    1974-01-01

    A detector of ultraviolet radiation for operation in a space vehicle which orbits through high intensity radiation areas is described. Two identical ultraviolet sensor tubes are mounted within a shield which limits to acceptable levels the amount of proton radiation reaching the sensor tubes. The shield has an opening which permits ultraviolet radiation to reach one of the sensing tubes. The shield keeps ultraviolet radiation from reaching the other sensor tube, designated the reference tube. The circuitry of the detector subtracts the output of the reference tube from the output of the sensing tube, and any portion of the output of the sensing tube which is due to proton radiation is offset by the output of the reference tube. A delay circuit in the detector prevents false alarms by keeping statistical variations in the proton radiation sensed by the two sensor tubes from developing an output signal.

  20. [Effect of long-wave ultraviolet light (UV-A) and medium-wave ultraviolet rays (UV-B) on human skin. Critical comparison].

    PubMed

    Raab, W

    1980-04-15

    When discussing the effects of ultraviolet radiation on human skin, one should carefully distinguish between the long wave ultraviolet light (UV-A) and the short wave radiations (UV-B and UV-C). Ultraviolet A induces immediate pigmentation but, if high energies are applied, a permanent pigmentation is elicited. This type of ultraviolet A-induced pigmentation has been called "spontaneous" pigmentation as no erythematous reaction is necessary to induce or accelerate melanine formation. Ultraviolet B provokes erythema and consecutive pigmentation. Upon chronic exposure, ultraviolet B causes the wellknown actinic damage of the skin and even provokes carcinoma. With exposures to the sunlight (global radiation), one should be most careful. The public must be informed extensively about the dangers of excessive sunbaths. The use of artificial "suns" with spectra between 260 and 400 nm is limited as it may cause the same type of damage as the global radiation. An exact schedule for use of artificial lamps is strongly recommended. After one cycle of exposures, an interruption is necessary until the next cycle of irradiations may start. Upon continual use for tanning of the skin, artificial lamps may provoke irreversible damage of the skin. Radiation sources with emission spectra of wavelengths between 315 and 400 nm exclusively are well suited for the induction of skin pigmentation (cosmetic use). Potent radiation such as UVASUN systems provoke a "pleasant" permanent pigmentation after exposures for less than one hour. The use of ultraviolet A (UV-A) does not carry any risk for the human skin.

  1. ULTRAVIOLET PROTECTIVE COMPOUNDS AS A RESPONSE TO ULTRAVIOLET RADIATION EXPOSURE

    EPA Science Inventory

    Life on Earth has evolved adaptations to many environmental stresses over the epochs. One consistent stress has been exposure to ultraviolet radiation. In response to UVR organisms have adapted myriad responses; behavioral, morphological and physiological. Behaviorally, some orga...

  2. Ecologic analysis of some immune-related disorders, including type 1 diabetes, in Australia: latitude, regional ultraviolet radiation, and disease prevalence.

    PubMed Central

    Staples, Judith A; Ponsonby, Anne-Louise; Lim, Lynette L-Y; McMichael, Anthony J

    2003-01-01

    The apparent immune-suppressive effect of ultraviolet radiation (UVR) has suggested that this environmental exposure may influence the development of immune-related disorders. Self-reported prevalence rates of type 1 diabetes mellitus, rheumatoid arthritis (RA), eczema/dermatitis, and asthma, from the 1995 Australian National Health Survey, were therefore examined by latitude and ambient level of UVR. A positive association of type 1 diabetes mellitus prevalence was found with both increasing southern latitude of residence (r = 0.77; p = 0.026) and decreasing regional annual ambient UVR (r= -0.80; p = 0.018); a 3-fold increase in prevalence from the northernmost region to the southernmost region was evident. In contrast, asthma correlated negatively with latitude (r = -0.72; p = 0.046), although the change in asthma prevalence from the north to the south of Australia was only 0.7-fold. For both RA and eczema/dermatitis, there were no statistically significant associations between latitude/UVR and disease prevalence. These ecologic data provide some support for a previously proposed beneficial effect of UVR on T-helper 1-mediated autoimmune disorders such as type 1 diabetes. The inverse association of type 1 diabetes prevalence with UVR is consistent with that previously reported for another autoimmune disease, multiple sclerosis, in Australia, and also with type 1 diabetes latitudinal gradients in the Northern Hemisphere. The finding also accords with photoimmunologic evidence of UVR-induced immunosuppression and may suggest a beneficial effect of UVR in reducing the incidence of such autoimmune conditions. In light of this study, analytic epidemiologic studies investigating risk of immune disorders in relation to personal UVR exposure in humans are required. PMID:12676609

  3. Ecologic analysis of some immune-related disorders, including type 1 diabetes, in Australia: latitude, regional ultraviolet radiation, and disease prevalence.

    PubMed

    Staples, Judith A; Ponsonby, Anne-Louise; Lim, Lynette L-Y; McMichael, Anthony J

    2003-04-01

    The apparent immune-suppressive effect of ultraviolet radiation (UVR) has suggested that this environmental exposure may influence the development of immune-related disorders. Self-reported prevalence rates of type 1 diabetes mellitus, rheumatoid arthritis (RA), eczema/dermatitis, and asthma, from the 1995 Australian National Health Survey, were therefore examined by latitude and ambient level of UVR. A positive association of type 1 diabetes mellitus prevalence was found with both increasing southern latitude of residence (r = 0.77; p = 0.026) and decreasing regional annual ambient UVR (r= -0.80; p = 0.018); a 3-fold increase in prevalence from the northernmost region to the southernmost region was evident. In contrast, asthma correlated negatively with latitude (r = -0.72; p = 0.046), although the change in asthma prevalence from the north to the south of Australia was only 0.7-fold. For both RA and eczema/dermatitis, there were no statistically significant associations between latitude/UVR and disease prevalence. These ecologic data provide some support for a previously proposed beneficial effect of UVR on T-helper 1-mediated autoimmune disorders such as type 1 diabetes. The inverse association of type 1 diabetes prevalence with UVR is consistent with that previously reported for another autoimmune disease, multiple sclerosis, in Australia, and also with type 1 diabetes latitudinal gradients in the Northern Hemisphere. The finding also accords with photoimmunologic evidence of UVR-induced immunosuppression and may suggest a beneficial effect of UVR in reducing the incidence of such autoimmune conditions. In light of this study, analytic epidemiologic studies investigating risk of immune disorders in relation to personal UVR exposure in humans are required.

  4. Effects of ultraviolet radiation on lattice imperfections in pyrolytic boron nitride.

    NASA Technical Reports Server (NTRS)

    Buckley, J. D.; Cooley, J. A.

    1971-01-01

    Pyrolitic boron nitride was exposed to 310 equivalent sun hours of ultraviolet radiation in a space environment simulator with the objective to evaluate its applicability as a pigment for a thermal control coating and to identify radiation damage using X-ray diffraction techniques. Lattice parameter comparisons show a definite increase in lattice imperfections in the crystal structure resulting from the ultraviolet irradiation. This sensitivity to radiation damage makes pyrolitic boron nitride unsuitable as a pigment for thermal control coating.

  5. Space environmental effects on polymeric materials

    NASA Technical Reports Server (NTRS)

    Kiefer, Richard L.; Orwoll, Robert A.

    1988-01-01

    Two of the major environmental hazards in the Geosynchronous Earth Orbit (GEO) are energetic charged particles and ultraviolet radiation. The charged particles, electrons and protons, range in energy from 0.1 to 4 MeV and each have a flux of 10 to the 8th sq cm/sec. Over a 30 year lifetime, materials in the GEO will have an absorbed dose from this radiation of 10 to the 10th rads. The ultraviolet radiation comes uninhibited from the sun with an irradiance of 1.4 kw/sq m. Radiation is known to initiate chain sission and crosslinking in polymeric materials, both of which affect their structural properties. The 30-year dose level from the combined radiation in the GEO exceeds the threshold for measurable damage in most polymer systems studied. Of further concern is possible synergistic effects from the simultaneous irradiation with charged particles and ultraviolet radiation. Most studies on radiation effects on polymeric materials use either electrons or ultraviolet radiation alone, or in a sequential combination.

  6. Effects of exposure to ultraviolet light on the development of Rana pipiens, the northern leopard frog

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Williams, J.J.; Wofford, H.W.

    1996-10-01

    The increase in ultraviolet light intensity levels due to ozone depletion recently has been linked to the decline in amphibian population. In this experiment, eggs and larvae of Rana pipiens were subjected to differing amounts of ultraviolet radiation to determine the effects of ultraviolet light on the development of amphibian tadpoles. The total length, length of body without tail, and maximum width of each specimen was recorded for a month of the tadpoles` development, including several measurements after the ultraviolet exposures were concluded. It was found that ultraviolet exposure significantly reduced the size of the organisms in comparison with themore » control group in all three measured areas. Ultraviolet radiation altered the health and appearance of the exposed organisms and was lethal at large amounts. This experiment showed that ultraviolet radiation could cause many problems in developing amphibians. By slowing their development and physically weakening predation, thus contributing to a decline in overall population levels.« less

  7. Research in extreme ultraviolet and far ultraviolet astronomy

    NASA Technical Reports Server (NTRS)

    Labov, S. E.

    1985-01-01

    Instruments designed to explore different aspects of far and extreme ultraviolet cosmic radiation were studied. The far ultraviolet imager (FUVI) was flown on the Aries sounding rocket. Its unique large format 75mm detector mapped out the far ultraviolet background radiation with a resolution of only a few arc minutes. Analysis of this data indicates to what extent the FUVI background is extra galactic in origin. A power spectrum of the spatial fluctuations will have direct consequences for galactic evolution.

  8. Characterization of photoluminescence spectra from poly allyl diglycol carbonate (CR-39) upon excitation with the ultraviolet radiation of various wavelengths

    NASA Astrophysics Data System (ADS)

    El Ghazaly, M.; Al-Thomali, Talal A.

    2013-04-01

    The induced photoluminescence (PL) from the π-conjugated polymer poly allyl diglycol carbonate (PADC) (CR-39) upon excitation with the ultraviolet radiation of different wavelengths was investigated. The absorption and attenuation coefficients of PADC (CR-39) were recorded using a UV-visible spectrometer. It was found that the absorption and attenuation coefficients of the PADC (CR-39) exhibit a strong dependence on the wavelength of ultraviolet radiation. The PL spectra were measured with a Flormax-4 spectrofluorometer (Horiba). PADC (CR-39) samples were excited by ultraviolet radiation with wavelengths in the range from 260 to 420 nm and the corresponding PL emission bands were recorded. The obtained results show a strong correlation between the PL and the excitation wavelength of ultraviolet radiation. The position of the fluorescence emission band peak was red shifted starting from 300 nm, which was increased with the increase in the excitation wavelength. The PL yield and its band peak height were increased with the increase in the excitation wavelength till 290 nm, thereafter they decreased exponentially with the increase in the ultraviolet radiation wavelength. These new findings should be considered carefully during the use of the PADC (CR-39) in the scientific applications and in using PADC (CR-39) in eyeglasses.

  9. Stage-dependent teratogenic and lethal effects exerted by ultraviolet B radiation on Rhinella (Bufo) arenarum embryos.

    PubMed

    Castañaga, Luis A; Asorey, Cynthia M; Sandoval, María T; Pérez-Coll, Cristina S; Argibay, Teresa I; Herkovits, Jorge

    2009-02-01

    The adverse effects of ultraviolet B radiation from 547.2 to 30,096 J/m2 on morphogenesis, cell differentiation, and lethality of amphibian embryos at six developmental stages were evaluated from 24 up to 168 h postexposure. The ultraviolet B radiation lethal dose 10, 50, and 90 values were obtained for all developmental stages evaluated. The lethal dose 50 values, considered as the dose causing lethality in the 50% of the organisms exposed, in J/m2 at 168 h postexposure, ranged from 2,307 to 18,930; gill circulation and blastula were the most susceptible and resistant stages, respectively. Ultraviolet B radiation caused malformations in all developmental stages but was significantly more teratogenic at the gill circulation and complete operculum stages. Moreover, at the gill circulation stage, even the lowest dose (547.2 J/m2) resulted in malformations to 100% of embryos. The most common malformations were persistent yolk plug, bifid spine, reduced body size, delayed development, asymmetry, microcephaly and anencephaly, tail and body flexures toward the irradiated side, agenesia or partial gill development, abnormal pigment distribution, and hypermotility. The stage-dependent susceptibility to ultraviolet B radiation during amphibian embryogenesis could be explained in the framework of evoecotoxicology, considering ontogenic features as biomarkers of environmental signatures of living forms ancestors during the evolutionary process. The stage-dependent susceptibility to ultraviolet B radiation on Rhinella (Bufo) arenarum embryos for both lethal and teratogenic effects could contribute to a better understanding of the role of the increased ultraviolet B radiation on worldwide amphibian populations decline.

  10. Method for generating extreme ultraviolet with mather-type plasma accelerators for use in Extreme Ultraviolet Lithography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hassanein, Ahmed; Konkashbaev, Isak

    A device and method for generating extremely short-wave ultraviolet electromagnetic wave uses two intersecting plasma beams generated by two plasma accelerators. The intersection of the two plasma beams emits electromagnetic radiation and in particular radiation in the extreme ultraviolet wavelength. In the preferred orientation two axially aligned counter streaming plasmas collide to produce an intense source of electromagnetic radiation at the 13.5 nm wavelength. The Mather type plasma accelerators can utilize tin, or lithium covered electrodes. Tin, lithium or xenon can be used as the photon emitting gas source.

  11. Angular distribution of ions and extreme ultraviolet emission in laser-produced tin droplet plasma

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chen, Hong; Duan, Lian; Lan, Hui

    Angular-resolved ion time-of-flight spectra as well as extreme ultraviolet radiation in laser-produced tin droplet plasma are investigated experimentally and theoretically. Tin droplets with a diameter of 150 μm are irradiated by a pulsed Nd:YAG laser. The ion time-of-flight spectra measured from the plasma formed by laser irradiation of the tin droplets are interpreted in terms of a theoretical elliptical Druyvesteyn distribution to deduce ion density distributions including kinetic temperatures of the plasma. The opacity of the plasma for extreme ultraviolet radiation is calculated based on the deduced ion densities and temperatures, and the angular distribution of extreme ultraviolet radiation is expressedmore » as a function of the opacity using the Beer–Lambert law. Our results show that the calculated angular distribution of extreme ultraviolet radiation is in satisfactory agreement with the experimental data.« less

  12. Angular distribution of ions and extreme ultraviolet emission in laser-produced tin droplet plasma

    NASA Astrophysics Data System (ADS)

    Chen, Hong; Wang, Xinbing; Duan, Lian; Lan, Hui; Chen, Ziqi; Zuo, Duluo; Lu, Peixiang

    2015-05-01

    Angular-resolved ion time-of-flight spectra as well as extreme ultraviolet radiation in laser-produced tin droplet plasma are investigated experimentally and theoretically. Tin droplets with a diameter of 150 μm are irradiated by a pulsed Nd:YAG laser. The ion time-of-flight spectra measured from the plasma formed by laser irradiation of the tin droplets are interpreted in terms of a theoretical elliptical Druyvesteyn distribution to deduce ion density distributions including kinetic temperatures of the plasma. The opacity of the plasma for extreme ultraviolet radiation is calculated based on the deduced ion densities and temperatures, and the angular distribution of extreme ultraviolet radiation is expressed as a function of the opacity using the Beer-Lambert law. Our results show that the calculated angular distribution of extreme ultraviolet radiation is in satisfactory agreement with the experimental data.

  13. Photoresist composition for extreme ultraviolet lithography

    DOEpatents

    Felter, T. E.; Kubiak, G. D.

    1999-01-01

    A method of producing a patterned array of features, in particular, gate apertures, in the size range 0.4-0.05 .mu.m using projection lithography and extreme ultraviolet (EUV) radiation. A high energy laser beam is used to vaporize a target material in order to produce a plasma which in turn, produces extreme ultraviolet radiation of a characteristic wavelength of about 13 nm for lithographic applications. The radiation is transmitted by a series of reflective mirrors to a mask which bears the pattern to be printed. The demagnified focused mask pattern is, in turn, transmitted by means of appropriate optics and in a single exposure, to a substrate coated with photoresists designed to be transparent to EUV radiation and also satisfy conventional processing methods. A photoresist composition for extreme ultraviolet radiation of boron carbide polymers, hydrochlorocarbons and mixtures thereof.

  14. Photosynthetic carbon reduction by seagrasses exposed to ultraviolet A radiation

    NASA Technical Reports Server (NTRS)

    1979-01-01

    The seagrasses Halophila engelmannii, Halodule wrightii, and Syringodium filiforme were examined for their intrinsic sensitivity to ultraviolet-A-UV-A and ultraviolet-B-UV-B radiation. The effect of UV-A on photosynthetically active radiation (PAR) was also determined. Ultraviolet-A and ultraviolet-B were studied with emphasis on the greater respective environmental consequence in terms of seagrass distribution and abundance. Results indicate that an intrinsic sensitivity to UV-A alone is apparent only in Halophila, while net photosynthesis in Halodule and Syringodium seems unaffected by the level of UV-A provided. The sensitivity of Halophila to UV-A in the absense of (PAR) indicates that the photosynthetic reaction does not need to be in operation for damage to occur. Other significant results are reported.

  15. Melanoma risk and survival among organ transplant recipients

    PubMed Central

    Robbins, Hilary A.; Clarke, Christina A.; Arron, Sarah T.; Tatalovich, Zaria; Kahn, Amy R.; Hernandez, Brenda Y.; Paddock, Lisa; Yanik, Elizabeth L.; Lynch, Charles F.; Kasiske, Bertram L.; Snyder, Jon; Engels, Eric A.

    2015-01-01

    Solid organ transplant recipients, who are medically immunosuppressed to prevent graft rejection, have increased melanoma risk, but risk factors and outcomes are incompletely documented. We evaluated melanoma incidence among 139,991 non-Hispanic white transplants using linked U.S. transplant-cancer registry data (1987–2010). We used standardized incidence ratios (SIRs) to compare incidence to the general population, and incidence rate ratios (IRRs) from multivariable Poisson models to assess risk factors. Separately, we compared post-melanoma survival among transplant recipients (N=182) and non-recipients (N=131,358) using multivariable Cox models. Among transplant recipients, risk of invasive melanoma (N=519) was elevated (SIR=2.20, 95%CI 2.01-2.39), especially for regional stage tumors (SIR=4.11, 95%CI 3.27–5.09). Risk of localized tumors was stable over time after transplantation, but higher with azathioprine maintenance therapy (IRR=1.35, 95%CI 1.03–1.77). Risk of regional/distant stage tumors peaked within 4 years following transplantation and increased with polyclonal antibody induction therapy (IRR=1.65, 95%CI 1.02–2.67). Melanoma-specific mortality was higher among transplant recipients than non-recipients (HR 2.98, 95%CI 2.26–3.93). Melanoma exhibits increased incidence and aggressive behavior under transplant-related immunosuppression. Some localized melanomas may result from azathioprine, which acts synergistically with ultraviolet radiation, while T-cell depleting induction therapies may promote late stage tumors. Our findings support sun safety practices and skin screening for transplant recipients. PMID:26270022

  16. DEMONSTRATION BULLETIN - ULTROX INTERNATIONAL, INC. ULTRAVIOLET RADIATION AND OXIDATION

    EPA Science Inventory

    The ultraviolet (UV) radiation/oxidation treatment technology developed by Ultrox International uses a combination of UV radiation, ozone, and hydrogen peroxide to oxidize organic compounds in water. Various operating parameters can be adjusted in the Ultrox® system to enhan...

  17. Inhibition of seagrass photosynthesis by ultraviolet-B radiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Trocine, R.P.; Rice, J.D.; Wells, G.N.

    1981-07-01

    Effects of ultraviolet-B radiation on the photosynthesis of seagrasses (Halophila engelmanni Aschers, Halodule wrightii Aschers, and Syringodium filiforme (Kuetz) were examined. The intrinsic tolerance of each seagrass to ultraviolet-B, the presence and effectiveness of photorepair mechanisms to ultraviolet-B-induced photosynthetic inhibition, and the role of epiphytic growth as a shield from ultraviolet-B were investigated. Halodule was found to possess the greatest photosynthetic tolerance for ultraviolet-B. Photosynthesis in Syringodium was slightly more sensitive to ultraviolet-B while Halophila showed relatively little photosynthetic tolerance. Evidence for a photorepair mechanism was found only in Halodule. Syringodium appeared to rely primarily on a thick epidermal cellmore » layer to reduce photosynthetic damage. Halophila seemed to have no morphological or photorepair capabilities to deal with ultraviolet-B. This species appeared to rely on epiphytic and detrital shielding and the shade provided by other seagrasses to reduce ultraviolet-B irradiation to tolerable levels. The presence of epiphytes on leaf surfaces was found to reduce the extent of photosynthetic inhibition from ultraviolet-B exposure in all species. Halophila appears to obtain an increased photosynthetic tolerance to ultraviolet-B as an indirect benefit of chloroplast clumping to avoid photo-oxidation by intense levels of photosynthetically active radiation.« less

  18. Examining Dermatologist Use and Opinions of Ultraviolet Radiation for Cosmetic and Medical Purposes.

    PubMed

    Sampson, Blake P; Secrest, Aaron M; Hansen, Christopher B; Geller, Alan C

    2018-02-01

    BACKGROUND: The commercial tanning industry has opposed efforts to educate the public on the risks of tanning as well as attempts to restrict minors' access to tanning services. Despite a paucity of supporting literature, statements from the tanning industry claiming that dermatologists routinely use in-office phototherapy for cosmetic treatments and refer patients to tanning salons have successfully derailed and defeated legislation in many states. OBJECTIVE: This study aims to evaluate dermatologist referrals for ultraviolet radiation for cosmetic and medical purposes via tanning beds or phototherapy, as well as their opinions on tanning, legislation, and ultraviolet radiation counseling practices. DESIGN: The study was conducted using a 10-question anonymous survey. SETTING: The participants were surveyed during meetings of three regional dermatologic societies. PARTICIPANTS: One hundred and fifty-two dermatologists attending society meetings participated in the study. MEASURES: The authors measured physician referrals, opinions, and recommendations regarding ultraviolet exposure. RESULTS: Zero physicians (0/152) recommended tanning salons for cosmetic reasons. These 152 dermatologists referred 458 (417 adult, 41 pediatric) out of an estimated 809,369 patients (0.057%) to tanning salons for medical treatment. Of these physicians, 76 out of 152 and 15 out of 152 reported referring at least one adult or one pediatric patient, respectively, within the last year. All respondents supported ultraviolet tanning legislation and discouraged cosmetic tanning. CONCLUSION: These findings directly contradict the assertion that dermatologists use ultraviolet radiation for cosmetic purposes or routinely refer patients to tanning salons. This study underscores the complex nature of ultraviolet radiation, as dermatologists infrequently utilize ultraviolet radiation for medical purposes and unanimously support restrictive legislation. In addition, these dermatologists counsel against cosmetic tanning and list tanning bed use among their highest concerns with regard to the health of pediatric patients.

  19. Examining Dermatologist Use and Opinions of Ultraviolet Radiation for Cosmetic and Medical Purposes

    PubMed Central

    Secrest, Aaron M.; Hansen, Christopher B.; Geller, Alan C.

    2018-01-01

    BACKGROUND: The commercial tanning industry has opposed efforts to educate the public on the risks of tanning as well as attempts to restrict minors’ access to tanning services. Despite a paucity of supporting literature, statements from the tanning industry claiming that dermatologists routinely use in-office phototherapy for cosmetic treatments and refer patients to tanning salons have successfully derailed and defeated legislation in many states. OBJECTIVE: This study aims to evaluate dermatologist referrals for ultraviolet radiation for cosmetic and medical purposes via tanning beds or phototherapy, as well as their opinions on tanning, legislation, and ultraviolet radiation counseling practices. DESIGN: The study was conducted using a 10-question anonymous survey. SETTING: The participants were surveyed during meetings of three regional dermatologic societies. PARTICIPANTS: One hundred and fifty-two dermatologists attending society meetings participated in the study. MEASURES: The authors measured physician referrals, opinions, and recommendations regarding ultraviolet exposure. RESULTS: Zero physicians (0/152) recommended tanning salons for cosmetic reasons. These 152 dermatologists referred 458 (417 adult, 41 pediatric) out of an estimated 809,369 patients (0.057%) to tanning salons for medical treatment. Of these physicians, 76 out of 152 and 15 out of 152 reported referring at least one adult or one pediatric patient, respectively, within the last year. All respondents supported ultraviolet tanning legislation and discouraged cosmetic tanning. CONCLUSION: These findings directly contradict the assertion that dermatologists use ultraviolet radiation for cosmetic purposes or routinely refer patients to tanning salons. This study underscores the complex nature of ultraviolet radiation, as dermatologists infrequently utilize ultraviolet radiation for medical purposes and unanimously support restrictive legislation. In addition, these dermatologists counsel against cosmetic tanning and list tanning bed use among their highest concerns with regard to the health of pediatric patients. PMID:29552275

  20. Photosynthetically active radiation (PAR) x ultraviolet radiation (UV) interact to initiate solar injury in apple

    USDA-ARS?s Scientific Manuscript database

    Sunburn or solar injury (SI) in apple is associated with high temperature, high visible light and ultraviolet radiation (UV). Fruit surface temperature (FST) thresholds for SI related disorders have been developed but there are no thresholds established for solar radiation. The objectives of the s...

  1. [Ultraviolet radiation and long term space flight].

    PubMed

    Wu, H B; Su, S N; Ba, F S

    2000-08-01

    With the prolongation of space flight, influences of various aerospace environmental factors on the astronauts become more and more severe, while ultraviolet radiation is lacking. Some studies indicated that low doses of ultraviolet rays are useful and essential for human body. In space flight, ultraviolet rays can improve the hygienic condition in the space cabin, enhance astronaut's working ability and resistance to unfavorable factors, prevent mineral metabolic disorders, cure purulent skin diseases and deallergize the allergens. So in long-term space flight, moderate amount of ultraviolet rays in the space cabin would be beneficial.

  2. Prediction of skin cancer occurrence by ultraviolet solar index

    PubMed Central

    Rivas, Miguel; Rojas, Elisa; Calaf, Gloria M.

    2012-01-01

    An increase in the amount of solar ultraviolet light that reaches the Earth is considered to be responsible for the worldwide increase in skin cancer. It has been reported that exposure to excessive levels of solar ultraviolet light has multiple effects, which can be harmful to humans. Experimental ultraviolet light measurements were obtained in several locations in Chile between 2006 and 2009 using wide-band solar light Biometer YES, calibrated according to World Meteorological Organization (WMO) criteria and integrated into the National Meteorological Center of Chile ultraviolet network (DMC). The aim of this study was to determine skin cancer rates in relation to experimental data accumulated during one year of studying the solar ultraviolet index in Chile, in order to explain the possible effect of radiation on skin cancer. The rate of skin cancer per 100,000 persons was considered in Arica, Santiago, Concepción and Valdivia and extrapolated to other cities. Results of the present study showed that the incidence of skin cancer was markedly correlated with accumulative ultraviolet radiation, and rates of skin cancer could be extrapolated to other locations in Chile. There is a steady increase in the rate of skin cancer in cities located nearest to the equator (low latitude) that receive greater accumulated solar ultraviolet radiation, due to the accumulative effects of this type of radiation on the skin. It can be concluded that Arica is a city at sea level that receives higher levels of ultraviolet solar radiation than other locations, which may explain the higher prevalence of skin cancer in the population of this location, compared with other cities in Chile. PMID:22741013

  3. Effect of DNA-injuring agents on B. stearothermophilus. Report 1. High resistance of B. stearothermophilus to N-nitroso-N-methylurea, ultraviolet and gamma radiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gainullina, S.M.; Gumanova, A.V.; Vinogradova, N.A.

    1978-01-01

    The effects of DNA-attacking agents on thermophilic microorganisms were investigated. Bacillus stearothermophilus were treated with N-nitroso-N-methylurea, ultraviolet radiation or gamma radiation. Survival curves were plotted.

  4. INTERACTIONS OF SOLAR ULTRAVIOLET RADIATION AND DISSOLVED ORGANIC MATTER IN FRESHWATER AND MARINE ENVIRONMENTS

    EPA Science Inventory

    Solar radiation provides the primary driving force for the biogeochemical cycles upon which life and climate depend. Recent studies have demonstrated that the absorption of solar radiation, especially 'm the ultraviolet spectral region, results in photochemical reactions that can...

  5. Assessment of the impact of increased solar ultraviolet radiation upon marine ecosystems

    NASA Technical Reports Server (NTRS)

    Worrest, R. C.; Vandyke, H.

    1978-01-01

    Reduction of the earth's ozone layer, with a resultant increase in transmission of solar ultraviolet radiation in the 290 to 320nm waveband (UV-B), via space shuttle operations through the stratosphere is considered. It is shown that simulated solar ultraviolet radiation can, under experimental conditions, detrimentally affect the marine organisms that form the base of the food web of oceanic and estuarine ecosystems. Whether a small increase in biologically harmful ultraviolet radiation might overwhelm these mechanisms and produce changes that will have damaging consequences to the biosphere is discussed. The potential for irreversible damage to the productivity, structure and/or functioning of a model estuarine ecosystem by increased UV-B radiation and whether these ecosystems are highly stable or amenable to adaptive change is studied. Data are provided to assess the potential impact upon marine ecosystems if space shuttle operations contribute to a reduction of the stratospheric ozone layer and the sensitivity of key community components to increased UV-B radiation is examined.

  6. Effects of solar ultraviolet radiations on Bacillus subtilis spores and T-7 bacteriophage

    NASA Technical Reports Server (NTRS)

    Spizizen, J.; Isherwood, J. E.; Taylor, G. R.

    1975-01-01

    Spores of Bacillus subtilis HA 101 and the DNA polymerase I-defective mutant HA 101 (59)F were exposed to selected wavelengths of solar ultraviolet light and space vacuum during the return of Apollo 16. In addition, coliphage T-7 suspensions were exposed to solar ultraviolet radiation as part of the Microbial Response to Space Environment Experiment. Optical filters were employed to provide different energy levels at wavelengths 254 nm and 280 nm. Dose-response curves for lethal and mutagenic effects were compared with ground-based data. A close parallel was observed between the results of solar radiation and ground tests with spores of the two strains. However, significantly greater inactivation of T-7 bacteriophage was observed after exposure to solar ultraviolet radiation.

  7. Inhibition of seagrass photosynthesis by ultraviolet-B radiation.

    PubMed

    Trocine, R P; Rice, J D; Wells, G N

    1981-07-01

    Effects of ultraviolet-B radiation on the photosynthesis of seagrasses (Halophila engelmanni Aschers, Halodule wrightii Aschers, and Syringodium filiforme Kütz) were examined. The intrinsic tolerance of each seagrass to ultraviolet-B, the presence and effectiveness of photorepair mechanisms to ultraviolet-B-induced photosynthetic inhibition, and the role of epiphytic growth as a shield from ultraviolet-B were investigated.Halodule was found to possess the greatest photosynthetic tolerance for ultraviolet-B. Photosynthesis in Syringodium was slightly more sensitive to ultraviolet-B while Halophila showed relatively little photosynthetic tolerance. Evidence for a photorepair mechanism was found only in Halodule. This mechanism effectively attenuated photosynthetic inhibition induced by ultraviolet-B dose rates and dosages in excess of natural conditions. Syringodium appeared to rely primarily on a thick epidermal cell layer to reduce photosynthetic damage. Halophila seemed to have no morphological or photorepair capabilities to deal with ultraviolet-B. This species appeared to rely on epiphytic and detrital shielding and the shade provided by other seagrasses to reduce ultraviolet-B irradiation to tolerable levels. The presence of epiphytes on leaf surfaces was found to reduce the extent of photosynthetic inhibition from ultraviolet-B exposure in all species.Observations obtained in this study seem to suggest the possibility of anthocyanin and/or other flavonoid synthesis as an adaptation to long term ultraviolet-B irradiation by these species. In addition, Halophila appears to obtain an increased photosynthetic tolerance to ultraviolet-B as an indirect benefit of chloroplast clumping to avoid photo-oxidation by intense levels of photosynthetically active radiation.

  8. Effect of Lot Variability on Ultraviolet Radiation Inactivation Kinetics of Cryptosporidium parvum Oocysts

    EPA Science Inventory

    Numerous studies have demonstrated the efficiency of ultraviolet (UV) radiation for the inactivation of oocysts of Cryptosporidium parvum. In these studies inactivation is measured as reduction in oocysts. A primary goal is to estimate the UV radiation required to achiev...

  9. The impact of skin colour on human photobiological responses.

    PubMed

    Fajuyigbe, Damilola; Young, Antony R

    2016-11-01

    Terrestrial solar ultraviolet radiation (UVR) exerts both beneficial and adverse effects on human skin. Epidemiological studies show a lower incidence of skin cancer in people with pigmented skins compared to fair skins. This is attributed to photoprotection by epidermal melanin, as is the poorer vitamin D status of those with darker skins. We summarize a wide range of photobiological responses across different skin colours including DNA damage and immunosuppression. Some studies show the generally modest photoprotective properties of melanin, but others show little or no effect. DNA photodamage initiates non-melanoma skin cancer and is reduced by a factor of about 3 in pigmented skin compared with white skin. This suggests that if such a modest reduction in DNA damage can result in the significantly lower skin cancer incidence in black skin, the use of sunscreen protection might be extremely beneficial for susceptible population. Many contradictory results may be explained by protocol differences, including differences in UVR spectra and exposure protocols. We recommend that skin type comparisons be done with solar-simulated radiation and standard erythema doses or physical doses (J/m 2 ) rather than those based solely on clinical endpoints such as minimal erythema dose (MED). © 2016 The Authors. Pigment Cell & Melanoma Research Published by John Wiley & Sons Ltd.

  10. Evaluating optical hazards from plasma arc cutting.

    PubMed

    Glassford, Eric; Burr, Gregory

    2018-01-01

    The Health Hazard Evaluation Program of the National Institute for Occupational Safety and Health evaluated a steel building materials manufacturer. The employer requested the evaluation because of concerns about optical radiation hazards from a plasma arc cutting system and the need to clarify eye protection requirements for plasma operators, other employees, and visitors. The strength of the ultraviolet radiation, visible radiation (light), and infrared radiation generated by the plasma arc cutter was measured at various distances from the source and at different operating amperages. Investigators also observed employees performing the plasma arc cutting. Optical radiation above safe levels for the unprotected eyes in the ultraviolet-C, ultraviolet-B, and visible light ranges were found during plasma arc cutting. In contrast, infrared and ultraviolet-A radiation levels during plasma arc cutting were similar to background levels. The highest non-ionizing radiation exposures occurred when no welding curtains were used. A plasma arc welding curtain in place did not eliminate optical radiation hazards to the plasma arc operator or to nearby employees. In most instances, the measured intensities for visible light, UV-C, and UV-B resulted in welding shade lens numbers that were lower than those stipulated in the OSHA Filter Lenses for Protection Against Radiant Energy table in 29 CFR 1910.133(a)(5). [1] Investigators recommended using a welding curtain that enclosed the plasma arc, posting optical radiation warning signs in the plasma arc cutter area, installing audible or visual warning cues when the plasma arc cutter was operating, and using welding shades that covered the plasma arc cutter operator's face to protect skin from ultraviolet radiation hazards.

  11. QUALITY ASSURANCE AND SITE MANAGEMENT FOR PRIMENET AND URBAN ULTRAVIOLET RADIATION RESEARCH MONITORING PROGRAM.

    EPA Science Inventory

    Because exposure to ultraviolet (UV) radiation is an ecosystem stressor and poses a human health risk, the National Exposure Research Laboratory (NERL) has undertaken a research program to measure the intensity of UV-B radiation at various locations throughout the U.S. In Septem...

  12. 21 CFR 101.76 - Health claims: fiber-containing grain products, fruits, and vegetables and cancer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... obesity, alcohol consumption, ultraviolet or ionizing radiation, exposure to cancer-causing chemicals, and..., overweight and obesity, alcohol consumption, ultraviolet or ionizing radiation, exposure to cancer causing...

  13. 21 CFR 101.76 - Health claims: fiber-containing grain products, fruits, and vegetables and cancer.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... obesity, alcohol consumption, ultraviolet or ionizing radiation, exposure to cancer-causing chemicals, and..., overweight and obesity, alcohol consumption, ultraviolet or ionizing radiation, exposure to cancer causing...

  14. 21 CFR 101.76 - Health claims: fiber-containing grain products, fruits, and vegetables and cancer.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... obesity, alcohol consumption, ultraviolet or ionizing radiation, exposure to cancer-causing chemicals, and..., overweight and obesity, alcohol consumption, ultraviolet or ionizing radiation, exposure to cancer causing...

  15. 21 CFR 101.76 - Health claims: fiber-containing grain products, fruits, and vegetables and cancer.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... obesity, alcohol consumption, ultraviolet or ionizing radiation, exposure to cancer-causing chemicals, and..., overweight and obesity, alcohol consumption, ultraviolet or ionizing radiation, exposure to cancer causing...

  16. 21 CFR 101.76 - Health claims: fiber-containing grain products, fruits, and vegetables and cancer.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... obesity, alcohol consumption, ultraviolet or ionizing radiation, exposure to cancer-causing chemicals, and..., overweight and obesity, alcohol consumption, ultraviolet or ionizing radiation, exposure to cancer causing...

  17. Measurements of Solar Ultraviolet Radiation Exposure at Work and at Leisure in Danish Workers.

    PubMed

    Grandahl, Kasper; Eriksen, Paul; Ibler, Kristina Sophie; Bonde, Jens Peter; Mortensen, Ole Steen

    2018-03-30

    Exposure to solar ultraviolet radiation is the main cause of skin cancer and may well present an occupational health and safety problem. In Denmark, skin cancer is a common disease in the general population, but detailed data on solar ultraviolet radiation exposure among outdoor workers are lacking. The aim of this study was to provide objective measurements of solar ultraviolet radiation exposure on working days and at leisure and compare levels of exposure between groups of mainly outdoor, equal-parts-outdoor-and-indoor and indoor workers. To this end, UV-B dosimeters with an aluminum gallium nitride (AlGaN) photodiode detector were used to measure the solar ultraviolet radiation exposure of 457 workers in the Danish summer season. Presented as semi-annual standard erythemal dose (SED) on working days, respectively, at leisure, the results are for mainly outdoor workers 214.2 SED and 64.8 SED, equal-parts-outdoor-and-indoor workers 131.4 SED and 64.8 SED, indoor workers 55.8 SED and 57.6 SED. The daily SED by month is significantly different (α = 0.05) between mainly outdoor, equal-parts-outdoor-and-indoor and indoor workers and across professional groups; some of which are exposed at very high levels that is roofers 361.8 SED. These findings substantiate that exposure to solar ultraviolet radiation is indeed an occupational health and safety problem in Denmark. © 2018 The Authors. Photochemistry and Photobiology published by Wiley Periodicals, Inc. on behalf of American Society for Photobiology.

  18. Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation

    PubMed Central

    Kadekaro, Ana Luisa; Leachman, Sancy; Kavanagh, Renny J.; Swope, Viki; Cassidy, Pamela; Supp, Dorothy; Sartor, Maureen; Schwemberger, Sandy; Babcock, George; Wakamatsu, Kazumasa; Ito, Shosuke; Koshoffer, Amy; Boissy, Raymond E.; Manga, Prashiela; Sturm, Richard A.; Abdel-Malek, Zalfa A.

    2010-01-01

    The melanocortin 1 receptor gene is a main determinant of human pigmentation, and a melanoma susceptibility gene, because its variants that are strongly associated with red hair color increase melanoma risk. To test experimentally the association between melanocortin 1 receptor genotype and melanoma susceptibility, we compared the responses of primary human melanocyte cultures naturally expressing different melanocortin 1 receptor variants to α-melanocortin and ultraviolet radiation. We found that expression of 2 red hair variants abolished the response to α-melanocortin and its photoprotective effects, evidenced by lack of functional coupling of the receptor, and absence of reduction in ultraviolet radiation-induced hydrogen peroxide generation or enhancement of repair of DNA photoproducts, respectively. These variants had different heterozygous effects on receptor function. Microarray data confirmed the observed differences in responses of melanocytes with functional vs. nonfunctional receptor to α-melanocortin and ultraviolet radiation, and identified DNA repair and antioxidant genes that are modulated by α-melanocortin. Our findings highlight the molecular mechanisms by which the melanocortin 1 receptor genotype controls genomic stability of and the mutagenic effect of ultraviolet radiation on human melanocytes.—Kadekaro, A. L., Leachman, S., Kavanagh, R. J., Swope, V., Cassidy, P., Supp, D., Sartor, M., Schwemberger, S., Babcock, G., Wakamatsu, K., Ito, S., Koshoffer, A., Boissy, R. E., Manga, P., Sturm, R. A., Abdel-Malek, Z. A. Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation. PMID:20519635

  19. Radiation environment study of near space in China area

    NASA Astrophysics Data System (ADS)

    Fan, Dongdong; Chen, Xingfeng; Li, Zhengqiang; Mei, Xiaodong

    2015-10-01

    Aerospace activity becomes research hotspot for worldwide aviation big countries. Solar radiation study is the prerequisite for aerospace activity to carry out, but lack of observation in near space layer becomes the barrier. Based on reanalysis data, input key parameters are determined and simulation experiments are tried separately to simulate downward solar radiation and ultraviolet radiation transfer process of near space in China area. Results show that atmospheric influence on the solar radiation and ultraviolet radiation transfer process has regional characteristic. As key factors such as ozone are affected by atmospheric action both on its density, horizontal and vertical distribution, meteorological data of stratosphere needs to been considered and near space in China area is divided by its activity feature. Simulated results show that solar and ultraviolet radiation is time, latitude and ozone density-variant and has complicated variation characteristics.

  20. Ultraviolet radiation, human health, and the urban forest

    Treesearch

    Gordon M. Heisler; Richard H. Grant

    2000-01-01

    Excess exposure to ultraviolet (UV) radiation from the sun, particularly the ultraviolet B (UVB) portion, has been linked with adverse effects on human health ranging from skin cancers to eye diseases such as cataracts. Trees may prevent even greater disease rates in humans by reducing UV exposure. Tree shade greatly reduces UV irradiance when both the sun and sky are...

  1. The effect of prescription eyewear on ocular exposure to ultraviolet radiation.

    PubMed Central

    Rosenthal, F S; Bakalian, A E; Taylor, H R

    1986-01-01

    Several studies have suggested that ultraviolet radiation in sunlight may cause cataracts and other eye disease. We evaluated the effect of prescription eyewear in attenuating ocular exposure to ultraviolet radiation (UVR) in the sunlight portions of the ultraviolet spectrum (295-350 nm). Using natural sunlight as the source, the attenuation was measured with two ultraviolet detectors, one sensitive to only UVB (295-315 nm) and one sensitive to both UVA and UVB (295-350 nm). A random sample of spectacles, spectacle lenses, and contact lenses was examined. The average transmission, as measured with either detector, was highest for soft contact lenses, followed by glass spectacle lenses, untinted hard contact lenses, and plastic spectacle lenses. Measurements performed with mannikins wearing spectacles showed that an average of 6.6 per cent of incident radiation reached the eye even when the lenses were covered with black opaque tape. The amount of exposure was increased substantially when the spectacles were moved 0.6 cm away from the forehead. The results show that the protection against ultraviolet exposure provided by prescription eyewear is highly variable and depends largely on its composition, size, and wearing position. PMID:3752323

  2. Nrf2 Activation Protects against Solar-Simulated Ultraviolet Radiation in Mice and Humans.

    PubMed

    Knatko, Elena V; Ibbotson, Sally H; Zhang, Ying; Higgins, Maureen; Fahey, Jed W; Talalay, Paul; Dawe, Robert S; Ferguson, James; Huang, Jeffrey T-J; Clarke, Rosemary; Zheng, Suqing; Saito, Akira; Kalra, Sukirti; Benedict, Andrea L; Honda, Tadashi; Proby, Charlotte M; Dinkova-Kostova, Albena T

    2015-06-01

    The transcription factor Nrf2 determines the ability to adapt and survive under conditions of electrophilic, oxidative, and inflammatory stress by regulating the expression of elaborate networks comprising nearly 500 genes encoding proteins with versatile cytoprotective functions. In mice, disruption of Nrf2 increases susceptibility to carcinogens and accelerates disease pathogenesis. Paradoxically, Nrf2 is upregulated in established human tumors, but whether this upregulation drives carcinogenesis is not known. Here we show that the incidence, multiplicity, and burden of solar-simulated UV radiation-mediated cutaneous tumors that form in SKH-1 hairless mice in which Nrf2 is genetically constitutively activated are lower than those that arise in their wild-type counterparts. Pharmacologic Nrf2 activation by topical biweekly applications of small (40 nmol) quantities of the potent bis(cyano enone) inducer TBE-31 has a similar protective effect against solar-simulated UV radiation in animals receiving long-term treatment with the immunosuppressive agent azathioprine. Genetic or pharmacologic Nrf2 activation lowers the expression of the pro-inflammatory factors IL6 and IL1β, and COX2 after acute exposure of mice to UV radiation. In healthy human subjects, topical applications of extracts delivering the Nrf2 activator sulforaphane reduced the degree of solar-simulated UV radiation-induced skin erythema, a quantifiable surrogate endpoint for cutaneous damage and skin cancer risk. Collectively, these data show that Nrf2 is not a driver for tumorigenesis even upon exposure to a very potent and complete carcinogen and strongly suggest that the frequent activation of Nrf2 in established human tumors is a marker of metabolic adaptation. ©2015 American Association for Cancer Research.

  3. Nrf2 activation protects against solar-simulated ultraviolet radiation in mice and humans

    PubMed Central

    Knatko, Elena V.; Ibbotson, Sally H.; Zhang, Ying; Higgins, Maureen; Fahey, Jed W.; Talalay, Paul; Dawe, Robert S.; Ferguson, James; Huang, Jeffrey T.-J.; Clarke, Rosemary; Zheng, Suqing; Saito, Akira; Kalra, Sukirti; Benedict, Andrea L.; Honda, Tadashi; Proby, Charlotte M.; Dinkova-Kostova, Albena T.

    2015-01-01

    The transcription factor Nrf2 determines the ability to adapt and survive under conditions of electrophilic, oxidative and inflammatory stress by regulating the expression of elaborate networks comprising nearly 500 genes encoding proteins with versatile cytoprotective functions. In mice, disruption of Nrf2 increases susceptibility to carcinogens and accelerates disease pathogenesis. Paradoxically, Nrf2 is upregulated in established human tumors, but whether this upregulation drives carcinogenesis is not known. Here we show that the incidence, multiplicity and burden of solar-simulated UV radiation-mediated cutaneous tumors that form in SKH-1 hairless mice in which Nrf2 is genetically constitutively activated, are lower than those that arise in their wild-type counterparts. Pharmacological Nrf2 activation by topical bi-weekly applications of small (40 nmol) quantities of the potent bis(cyano enone) inducer TBE-31 has a similar protective effect against solar-simulated UV radiation in animals receiving long-term treatment with the immunosuppressive agent azathioprine. Genetic or pharmacological Nrf2 activation lowers the expression of the pro-inflammatory factors interleukin (IL)-6 and IL-1β, and cyclooxygenase (COX)-2 after acute exposure of mice to UV radiation. In healthy human subjects, topical applications of extracts delivering the Nrf2 activator sulforaphane, reduced the degree of solar-simulated UV radiation-induced skin erythema, a quantifiable surrogate end-point for cutaneous damage and skin cancer risk. Collectively, these data show that Nrf2 is not a driver for tumorigenesis even upon exposure to a very potent and complete carcinogen, and strongly suggest that the frequent activation of Nrf2 in established human tumors is a marker of metabolic adaptation. PMID:25804610

  4. In situ gene expression profiling of the thermoacidophilic alga Cyanidioschyzon in relation to visible and ultraviolet irradiance.

    PubMed

    Skorupa, Dana J; Castenholz, Richard W; Mazurie, Aurélien; Carey, Charles; Rosenzweig, Frank; McDermott, Timothy R

    2014-06-01

    Ultraviolet and high-intensity visible radiation generate reactive intermediates that damage phototrophic microorganisms. In Yellowstone National Park, the thermoacidophilic alga Cyanidioschyzon exhibits an annual seasonal biomass fluctuation referred to as 'mat decline', where algal viability decreases as ultraviolet and visible irradiances increase during summer. We examined the role irradiance might play in mat decline using irradiance filters that uncouple ultraviolet and visible effects along with custom microarrays to study gene expression in situ. Of the 6507 genes, 88% showed no response to ultraviolet or visible, implying that at the biomolecular level, these algae inhabit a chemostat-like environment and is consistent with the near constant aqueous chemistry measured. The remaining genes exhibited expression changes linked to ultraviolet exposure, to increased visible radiation, or to the apparent combined effects of ultraviolet and visible. Expression of DNA repetitive elements was synchronized, being repressed by visible but also influenced by ultraviolet. At highest irradiance levels, these algae reduced transcription of genes encoding functions involved with DNA replication, photosynthesis and cell cycle progression but exhibited an uptick in activities related to repairing DNA damage. This corroborates known physiological responses to ultraviolet and visible radiation, and leads us to provisionally conclude that mat decline is linked to photoinhibition. © 2013 Society for Applied Microbiology and John Wiley & Sons Ltd.

  5. Inhibition of Seagrass Photosynthesis by Ultraviolet-B Radiation 1

    PubMed Central

    Trocine, Robert P.; Rice, John D.; Wells, Gary N.

    1981-01-01

    Effects of ultraviolet-B radiation on the photosynthesis of seagrasses (Halophila engelmanni Aschers, Halodule wrightii Aschers, and Syringodium filiforme Kütz) were examined. The intrinsic tolerance of each seagrass to ultraviolet-B, the presence and effectiveness of photorepair mechanisms to ultraviolet-B-induced photosynthetic inhibition, and the role of epiphytic growth as a shield from ultraviolet-B were investigated. Halodule was found to possess the greatest photosynthetic tolerance for ultraviolet-B. Photosynthesis in Syringodium was slightly more sensitive to ultraviolet-B while Halophila showed relatively little photosynthetic tolerance. Evidence for a photorepair mechanism was found only in Halodule. This mechanism effectively attenuated photosynthetic inhibition induced by ultraviolet-B dose rates and dosages in excess of natural conditions. Syringodium appeared to rely primarily on a thick epidermal cell layer to reduce photosynthetic damage. Halophila seemed to have no morphological or photorepair capabilities to deal with ultraviolet-B. This species appeared to rely on epiphytic and detrital shielding and the shade provided by other seagrasses to reduce ultraviolet-B irradiation to tolerable levels. The presence of epiphytes on leaf surfaces was found to reduce the extent of photosynthetic inhibition from ultraviolet-B exposure in all species. Observations obtained in this study seem to suggest the possibility of anthocyanin and/or other flavonoid synthesis as an adaptation to long term ultraviolet-B irradiation by these species. In addition, Halophila appears to obtain an increased photosynthetic tolerance to ultraviolet-B as an indirect benefit of chloroplast clumping to avoid photo-oxidation by intense levels of photosynthetically active radiation. Images PMID:16661893

  6. UV - GAITHERSBURG MD

    EPA Science Inventory

    Brewer 105 is located in Gaithersburg MD, measuring ultraviolet solar radiation. Irradiance and column ozone are derived from this data. Ultraviolet solar radiation is measured with a Brewer Mark IV, single-monochrometer, spectrophotometer manufactured by SCI-TEC Instruments, Inc...

  7. Inorganic volumetric light source excited by ultraviolet light

    DOEpatents

    Reed, Scott; Walko, Robert J.; Ashley, Carol S.; Brinker, C. Jeffrey

    1994-01-01

    The invention relates to a composition for the volumetric generation of radiation. The composition comprises a porous substrate loaded with a component capable of emitting radiation upon interaction with an exciting radiation. Preferably, the composition is an aerogel substrate loaded with a component, e.g., a phosphor, capable of interacting with exciting radiation of a first energy, e.g., ultraviolet light, to produce radiation of a second energy, e.g., visible light.

  8. Inorganic volumetric light source excited by ultraviolet light

    DOEpatents

    Reed, S.; Walko, R.J.; Ashley, C.S.; Brinker, C.J.

    1994-04-26

    The invention relates to a composition for the volumetric generation of radiation. The composition comprises a porous substrate loaded with a component capable of emitting radiation upon interaction with an exciting radiation. Preferably, the composition is an aerogel substrate loaded with a component, e.g., a phosphor, capable of interacting with exciting radiation of a first energy, e.g., ultraviolet light, to produce radiation of a second energy, e.g., visible light. 4 figures.

  9. Community-based Interventions to Prevent Skin Cancer: Two Community Guide Systematic Reviews

    PubMed Central

    Sandhu, Paramjit K.; Elder, Randy; Patel, Mona; Saraiya, Mona; Holman, Dawn M.; Perna, Frank; Smith, Robert A.; Buller, David; Sinclair, Craig; Reeder, Anthony; Makin, Jen; McNoe, Bronwen; Glanz, Karen

    2016-01-01

    Context Skin cancer is a preventable and commonly diagnosed cancer in the U.S. Excessive ultraviolet radiation exposure is a known cause of skin cancer. This article presents updated results of two types of interventions evaluated in a previously published Community Guide systematic review: multicomponent community-wide (MCCW) interventions and mass media (MM) interventions when used alone. Evidence acquisition Studies assessing MCCW and MM interventions to prevent skin cancer by reducing ultraviolet radiation exposure were evaluated using Community Guide systematic review methods. Relevant studies published between 1966 and 2013 were included and analyzed for this review. Evidence synthesis Seven studies evaluating the effectiveness of MCCW interventions showed a median increase in sunscreen use of 10.8 percentage points (interquartile interval=7.3, 23.2); a small decrease in ultraviolet radiation exposure; a decrease in indoor tanning device use of 4.0 percentage points (95% CI=2.5, 5.5); and mixed results for other protective behaviors. Four studies evaluating the effectiveness of MM interventions found that they generally led to improved ultraviolet protection behaviors among children and adults. Conclusions The available evidence showed that MCCW interventions are effective in reducing ultraviolet radiation exposure by increasing sunscreen use. There was, however, insufficient evidence to determine the effectiveness of MM interventions alone in reducing ultraviolet radiation exposure, indicating a continuing need for more research in this field to improve assessment of effectiveness. PMID:27647053

  10. Solar ultraviolet radiation from cancer induction to cancer prevention: solar ultraviolet radiation and cell biology.

    PubMed

    Tuorkey, Muobarak J

    2015-09-01

    Although decades have elapsed, researchers still debate the benefits and hazards of solar ultraviolet radiation (UVR) exposure. On the one hand, humans derive most of their serum 25-hydroxycholecalciferol [25(OH)D3], which has potent anticancer activity, from solar UVB radiation. On the other hand, people are more aware of the risk of cancer incidence associated with harmful levels of solar UVR from daily sunlight exposure. Epidemiological data strongly implicate UV radiation exposure as a major cause of melanoma and other cancers, as UVR promotes mutations in oncogenes and tumor-suppressor genes. This review highlights the impact of the different mutagenic effects of solar UVR, along with the cellular and carcinogenic challenges with respect to sun exposure.

  11. GASEOUS SCINTILLATION COUNTER

    DOEpatents

    Eggler, C.; Huddleston, C.M.

    1959-04-28

    A gaseous excitation counter for detecting the presence amd measuring the energy of subatomic particles and electromagnetic radiation is described. The counter includes a gas-tight chamber filled with an elemental gas capable of producing ultra-violet excitation quanta when irradiated with subatomic particles and electromagnetic radiation. The gas has less than one in a thousand parts ultra-violet absorbing contamination. When nuclear radiation ps present the ultra-violet light produced by the gas strikes a fluorescent material within the counter, responsive to produce visible excitation quanta, and photo-sensitive counting means detect the visible emission.

  12. Sunlight and Skin Cancer: Lessons from the Immune System

    PubMed Central

    Ullrich, Stephen E.

    2009-01-01

    The ultraviolet (UV) radiation in sunlight induces skin cancer development. Skin cancer is the most common form of human neoplasia. Estimates suggest that in excess of 1.5 million new cases of skin cancer (www.cancer.org/statistics) will be diagnosed in the United States this year Fortunately, because of their highly visible location, skin cancers are more rapidly diagnosed and more easily treated than other types of cancer. Be that as it may, approximately 10,000 Americans a year die from skin cancer, and the cost of treating skin cancer in the United States (both melanoma and non-melanoma skin cancer) is estimated to be in excess of $2.9 billion a year. In addition to causing skin cancer, UV radiation is also immune suppressive. In fact, data from studies with both experimental animals and biopsy proven skin cancer patients suggest that there is an association between the immune suppressive effects of UV radiation and its carcinogenic potential. Recent studies in my laboratory have focused on understanding the initial molecular events that induce immune suppression. We made two novel observations: First UV-induced keratinocyte-derived platelet activating factor plays a role in the induction of immune suppression. Second, cis-urocanic acid, a skin derived immunosuppressive compound mediates immune suppression by binding to serotonin receptors on target cells. Recent findings suggest that blocking the binding of these compounds to their receptors not only inhibits UV-induced immune suppression but it also interferes with skin cancer induction. PMID:17443748

  13. The ultraviolet radiation environment of pollen and its effect on pollen germination

    NASA Technical Reports Server (NTRS)

    1981-01-01

    The damage to pollen caused by natural ultraviolet radiation was investigated. Experimental and literature research into the UV radiation environment is reported. Viability and germination of wind and insect pollinated species were determined. Physiological, developmental, and protective factors influencing UV sensitivity of binucleate, advanced binucleate, and trinucleate pollen grains are compared.

  14. UV - EVERGLADES NATIONAL PARK FL

    EPA Science Inventory

    Brewer 135 is located in Everglades NP, measuring ultraviolet solar radiation. Irradiance and column ozone are derived from this data. Ultraviolet solar radiation is measured with a Brewer Mark IV, single-monochrometer, spectrophotometer manufactured by SCI-TEC Instruments, Inc. ...

  15. UV - THEODORE ROOSEVELT NATIONAL PARK ND

    EPA Science Inventory

    Brewer 131 is located in Theodore Roosevelt NP (South Section), measuring ultraviolet solar radiation. Irradiance and column ozone are derived from this data. Ultraviolet solar radiation is measured with a Brewer Mark IV, single-monochrometer, spectrophotometer manufactured by SC...

  16. Coordinated ultraviolet and radio observations of selected nearby stars

    NASA Technical Reports Server (NTRS)

    Lang, Kenneth R.

    1987-01-01

    All of the US2 shifts assigned were successfully completed with simultaneous International Ultraviolet Explorer (IUE) and the Very Large Array (VLA) observations of the proposed target stars. The target stars included dwarf M flare stars and RS CVn stars. The combined ultraviolet (IUE) and microwave (VLA) observations have provided important new insights to the radiation mechanisms at these two widely-separated regions of the electromagnetic spectrum. The VLA results included the discovery of narrow-band microwave radiation and rapid time variations in the microwave radiation of dwarf M flare stars. The results indicate that conventional radiation mechanisms cannot explain the microwave emission from these stars. In general, ultraviolet variations and bursts occur when no similar variations are detected at microwave wavelengths and vice versa. Although these is some overlap, the variations in these two spectral regions are usually uncorrelated, suggesting that there is little interaction between the activity centers at the two associated atmospheric levels.

  17. Solar simulated ultraviolet radiation damages murine neonatal skin and alters Langerhans cell development, but does not induce inflammation.

    PubMed

    McGee, Heather M; Dharmadasa, Thanuja; Woods, Gregory M

    2009-06-01

    Development of melanoma has been linked to excessive childhood exposure to sunlight. As neonates have a relatively underdeveloped immune system, it is likely that the immune system reacts differently to the exposure, leading to alterations in this development. This study was designed to assess changes in development of the skin immune system following neonatal irradiation. Ultraviolet radiation exposure led to relative depletion of Langerhans cells, however this was not due to migration or cell death, but rather restriction of Langerhans cells populating the epidermis. During this time, there was evidence of cellular damage, however there was no induction of an inflammatory response. It therefore appears that neonatal exposure to ultraviolet radiation leads to a skew towards a tolerogenic immune response, which may lead to a reduced ability to respond to ultraviolet radiation-induced tumours.

  18. Understanding the Early Evolution of M dwarf Extreme Ultraviolet Radiation

    NASA Astrophysics Data System (ADS)

    Peacock, Sarah; Barman, Travis; Shkolnik, Evgenya

    2015-11-01

    The chemistry and evolution of planetary atmospheres depends on the evolution of high-energy radiation emitted by its host star. High levels of extreme ultraviolet (EUV) radiation can drastically alter the atmospheres of terrestrial planets through ionizing, heating, expanding, chemically modifying and eroding them during the first few billion years of a planetary lifetime. While there is evidence that stars emit their highest levels of far and near ultraviolet (FUV; NUV) radiation in the earliest stages of their evolution, we are currently unable to directly measure the EUV radiation. Most previous stellar atmosphere models under-predict FUV and EUV emission from M dwarfs; here we present new models for M stars that include prescriptions for the hot, lowest density atmospheric layers (chromosphere, transition region and corona), from which this radiation is emitted. By comparing our model spectra to GALEX near and far ultraviolet fluxes, we are able to predict the evolution of EUV radiation for M dwarfs from 10 Myr to a few Gyr. This research is the next major step in the HAZMAT (HAbitable Zones and M dwarf Activity across Time) project to analyze how the habitable zone evolves with the evolving properties of stellar and planetary atmospheres.

  19. Method and apparatus for producing durationally short ultraviolet or x-ray laser pulses

    DOEpatents

    MacGowan, B.J.; Matthews, D.L.; Trebes, J.E.

    1987-05-05

    A method and apparatus is disclosed for producing ultraviolet or x- ray laser pulses of short duration. An ultraviolet or x-ray laser pulse of long duration is progressively refracted, across the surface of an opaque barrier, by a streaming plasma that is produced by illuminating a solid target with a pulse of conventional line focused high power laser radiation. The short pulse of ultraviolet or x-ray laser radiation, which may be amplified to high power, is separated out by passage through a slit aperture in the opaque barrier.

  20. Bioactive grape proanthocyanidins enhance immune reactivity in UV-irradiated skin through functional activation of dendritic cells in mice

    PubMed Central

    Vaid, Mudit; Singh, Tripti; Prasad, Ram; Elmets, Craig A.; Xu, Hui; Katiyar, Santosh K.

    2013-01-01

    Ultraviolet (UV) radiation-induced immunosuppression has been implicated in skin carcinogenesis. Grape seed proanthocyanidins (GSPs) have anti-skin carcinogenic effects in mice and GSPs-fed mice exhibit a reduction in UV-induced suppression of allergic contact hypersensitivity (CHS), a prototypic T cell-mediated response. Here, we report that dietary GSPs did not inhibit UVB-induced suppression of CHS in xeroderma pigmentosum complementation group A (XPA)-deficient mice, which lack nucleotide excision repair mechanisms. GSPs enhanced repair of UVB-induced DNA damage (cyclobutane pyrimidine dimers) in wild-type, but not XPA-deficient, dendritic cells (DCs). Co-culture of CD4+ T cells with DCs from UVB-irradiated wild-type mice resulted in suppression of T-cell proliferation and secretion of Th-1 type cytokines that was ameliorated when the DCs were obtained from GSPs-fed mice; whereas, DCs obtained from GSPs-fed XPA-KO mice failed to restore T-cell proliferation. In adoptive transfer experiments, donor DCs were positively selected from the draining lymph nodes of UVB-exposed donor mice that were sensitized to 2,4, dinitrofluorobenzene were transferred into naïve recipient mice and the CHS response assessed. Naïve recipients that received DCs from UVB-exposed wild-type donors that had been fed GSPs exhibited a full CHS response, whereas no significant CHS was observed in mice that received DCs from XPA-KO mice fed GSPs. These results suggest that GSPs prevent UVB-induced immunosuppression through DNA repair-dependent functional activation of dendritic cells in mice. PMID:23321928

  1. CHARACTERIZATION OF RELATIVE SENSITIVITY OF AMPHIBIANS TO ULTRAVIOLET RADIATION

    EPA Science Inventory

    Different studies have demonstrated that solar ultraviolet (UV) radiation can adversely affect survival and development of embryonic and larval amphibians. However, because of among-laboratory variations in exposure profiles (artificial vs. natural sunlight; natural sunlight at d...

  2. Ultra-violet radiation is responsible for the differences in global epidemiology of chickenpox and the evolution of varicella-zoster virus as man migrated out of Africa.

    PubMed

    Rice, Philip S

    2011-04-23

    Of the eight human herpes viruses, varicella-zoster virus, which causes chickenpox and zoster, has a unique epidemiology. Primary infection is much less common in children in the tropics compared with temperate areas. This results in increased adult susceptibility causing outbreaks, for example in health-care workers migrating from tropical to temperate countries. The recent demonstration that there are different genotypes of varicella-zoster virus and their geographic segregation into tropical and temperate areas suggests a distinct, yet previously unconsidered climatic factor may be responsible for both the clinical and molecular epidemiological features of this virus infection. Unlike other human herpes viruses, varicella-zoster virus does not require intimate contact for infection to occur indicating that transmission may be interrupted by a geographically restricted climatic factor. The factor with the largest difference between tropical and temperate zones is ultra-violet radiation. This could reduce the infectiousness of chickenpox cases by inactivating virus in vesicles, before or after rupture. This would explain decreased transmissibility in the tropics and why the peak chickenpox incidence in temperate zones occurs during winter and spring, when ultra-violet radiation is at its lowest. The evolution of geographically restricted genotypes is also explained by ultra-violet radiation driving natural selection of different virus genotypes with varying degrees of resistance to inactivation, tropical genotypes being the most resistant. Consequently, temperate viruses should be more sensitive to its effects. This is supported by the observation that temperate genotypes are found in the tropics only in specific circumstances, namely where ultra-violet radiation has either been excluded or significantly reduced in intensity. The hypothesis is testable by exposing different virus genotypes to ultra-violet radiation and quantifying virus survival by plaque forming units or quantitative mRNA RT-PCR. The ancestral varicella-zoster virus, most probably a tropical genotype, co-migrated with man as he left Africa approximately 200,000 years ago. For this virus to have lost the selective advantage of resistance to ultra-violet radiation, the hypothesis would predict that the temperate, ultra-violet sensitive virus should have acquired another selective advantage as an evolutionary trade-off. One obvious advantage could be an increased reactivation rate as zoster to set up more rounds of chickenpox transmission. If this were so, the mechanism responsible for resistance to ultra-violet radiation might also be involved in reactivation and latency. This could then provide the first insight into a genetic correlate of the survival strategy of this virus.

  3. Quantifying the effects of corn growth and physiological responses to Ultraviolet-B radiation for modeling

    USDA-ARS?s Scientific Manuscript database

    To understand the consequences of rising levels of Ultraviolet-B (UV-B) radiation on maize (Zea mays L.), two experiments were conducted using sunlit plant growth chambers at a wide range UV-B radiation. Maize cultivars Terral-2100 and DKC 65-44 were grown in 2003 and 2008, respectively, at four le...

  4. Ultraviolet radiation changes

    NASA Technical Reports Server (NTRS)

    Mckenzie, Richard L.; Frederick, John E.; Ilyas, Mohammad; Filyushkin, V.; Wahner, Andreas; Stamnes, K.; Muthusubramanian, P.; Blumthaler, M.; Roy, Colin E.; Madronich, Sasha

    1991-01-01

    A major consequence of ozone depletion is an increase in solar ultraviolet (UV) radiation received at the Earth's surface. This chapter discusses advances that were made since the previous assessment (World Meteorological Organization (WMO)) to our understanding of UV radiation. The impacts of these changes in UV on the biosphere are not included, because they are discussed in the effects assessment.

  5. Importance of biologically active aurora-like ultraviolet emission: stochastic irradiation of Earth and Mars by flares and explosions.

    PubMed

    Smith, David S; Scalo, John; Wheeler, J Craig

    2004-10-01

    Habitable planets will be subject to intense sources of ionizing radiation and fast particles from a variety of sources--from the host star to distant explosions--on a variety of timescales. Monte Carlo calculations of high-energy irradiation suggest that the surfaces of terrestrial-like planets with thick atmospheres (column densities greater than about 100 g cm(-2)) are well protected from directly incident X-rays and gamma-rays, but we find that sizeable fractions of incident ionizing radiation from astrophysical sources can be redistributed to biologically and chemically important ultraviolet wavelengths, a significant fraction of which can reach the surface. This redistribution is mediated by secondary electrons, resulting from Compton scattering and X-ray photoabsorption, the energies of which are low enough to excite and ionize atmospheric molecules and atoms, resulting in a rich aurora-like spectrum. We calculate the fraction of energy redistributed into biologically and chemically important wavelength regions for spectra characteristic of stellar flares and supernovae using a Monte-Carlo transport code and then estimate the fraction of this energy that is transmitted from the atmospheric altitudes of redistribution to the surface for a few illustrative cases. For atmospheric models corresponding to the Archean Earth, we assume no significant ultraviolet absorbers, only Rayleigh scattering, and find that the fraction of incident ionizing radiation that is received at the surface in the form of redistributed ultraviolet in the biologically relevant 200-320 nm region (UV-C and UV-B bands) can be up to 4%. On the present-day Earth with its ultraviolet ozone shield, this fraction is found to be 0.2%. Both values are many orders of magnitude higher than the fraction of direct ionizing radiation reaching the surface. This result implies that planetary organisms will be subject to mutationally significant, if intermittent, fluences of UV-B and harder radiation even in the presence of a narrow-band ultraviolet shield like ozone. We also calculate the surficial transmitted fraction of ionizing radiation and redistributed ultraviolet radiation for two illustrative evolving Mars atmospheres whose initial surface pressures were 1 bar. We discuss the frequency with which redistributed ultraviolet flux from parent star flares exceeds the parent star ultraviolet flux at the planetary surface. We find that the redistributed ultraviolet from parent star flares is probably a fairly rare intermittent event for habitable zone planets orbiting solar-type stars except when they are young, but should completely dominate the direct steady ultraviolet radiation from the parent star for planets orbiting all stars less massive than about 0.5 solar masses. Our results suggest that coding organisms on such planets (and on the early Earth) may evolve very differently than on contemporary Earth, with diversity and evolutionary rate controlled by a stochastically varying mutation rate and frequent hypermutation episodes.

  6. Improving Assessment of Lifetime Solar Ultraviolet Radiation Exposure in Epidemiologic Studies: Comparison of Ultraviolet Exposure Assessment Methods in a Nationwide United States Occupational Cohort.

    PubMed

    Little, Mark P; Tatalovich, Zaria; Linet, Martha S; Fang, Michelle; Kendall, Gerald M; Kimlin, Michael G

    2018-06-13

    Solar ultraviolet radiation is the primary risk factor for skin cancers and sun-related eye disorders. Estimates of individual ambient ultraviolet irradiance derived from ground-based solar measurements and from satellite measurements have rarely been compared. Using self-reported residential history from 67,189 persons in a nationwide occupational US radiologic technologists cohort, we estimated ambient solar irradiance using data from ground-based meters and noontime satellite measurements. The mean distance-moved from city of longest residence in childhood increased from 137.6 km at ages 13-19 to 870.3 km at ages ≥65, with corresponding increases in absolute latitude-difference moved. At ages 20/40/60/80, the Pearson/Spearman correlation coefficients of ground-based and satellite-derived solar potential ultraviolet exposure, using irradiance and cumulative radiant-exposure metrics, were high (=0.87-0.92). There was also moderate correlation (Pearson/Spearman correlation coefficients=0.51-0.60) between irradiance at birth and at last-known address, for ground-based and satellite data. Satellite-based lifetime estimates of ultraviolet radiation were generally 14-15% lower than ground-based estimates, albeit with substantial uncertainties, possibly because ground-based estimates incorporate fluctuations in cloud and ozone, which are incompletely incorporated in the single noontime satellite-overpass ultraviolet value. If confirmed elsewhere, the findings suggest that ground-based estimates may improve exposure-assessment accuracy and potentially provide new insights into ultraviolet-radiation-disease relationships in epidemiologic studies. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  7. Gage measures total radiation, including vacuum UV, from ionized high-temperature gases

    NASA Technical Reports Server (NTRS)

    Wood, A. D.

    1969-01-01

    Transient-heat transfer gage measures the total radiation intensity from vacuum ultraviolet and ionized high temperature gases. The gage includes a sensitive piezoelectric crystal that is completely isolated from any ionized flow and vacuum ultraviolet irradiation.

  8. Psoriasis and ultraviolet radiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Farber, E.M.; Nall, L.

    1993-09-01

    Prevention and detection screening programs as a public health service in curtailing the ever-increasing incidence of all forms of skin cancer are reviewed. The effect of solar and artificial ultraviolet radiation on the general population and persons with psoriasis is examined. 54 refs.

  9. Comprehensive Review of Ultraviolet Radiation and the Current Status on Sunscreens

    PubMed Central

    Moon, Summer; Armstrong, Frank

    2012-01-01

    In the past, manufacturers’ labeling of sunscreen varied greatly, confusing the consumers regarding efficacy and the appropriate photoprotection provided by their products. Therefore, in June 2011, the United States Food and Drug Administration issued new guidelines for sunscreen labeling. Sunscreen products are over-the-counter drugs; therefore, they are regulated by the United States Food and Drug Administration to determine safety, efficacy, and labeling. This article discusses ultraviolet radiation and the positive and negative effects of ultraviolet radiation, provides a review of sunscreens, and discusses the new United States Food and Drug Administration regulations for sunscreens. PMID:23050030

  10. Biotechnological and industrial significance of cyanobacterial secondary metabolites.

    PubMed

    Rastogi, Rajesh P; Sinha, Rajeshwar P

    2009-01-01

    Cyanobacteria are considered to be a rich source of novel metabolites of a great importance from a biotechnological and industrial point of view. Some cyanobacterial secondary metabolites (CSMs), exhibit toxic effects on living organisms. A diverse range of these cyanotoxins may have ecological roles as allelochemicals, and could be employed for the commercial development of compounds with applications such as algaecides, herbicides and insecticides. Recently, cyanobacteria have become an attractive source of innovative classes of pharmacologically active compounds showing interesting and exciting biological activities ranging from antibiotics, immunosuppressant, and anticancer, antiviral, antiinflammatory to proteinase-inhibiting agents. A different but not less interesting property of these microorganisms is their capacity of overcoming the toxicity of ultraviolet radiation (UVR) by means of UV-absorbing/screening compounds, such as mycosporine-like amino acids (MAAs) and scytonemin. These last two compounds are true 'multipurpose' secondary metabolites and considered to be natural photoprotectants. In this sense, they may be biotechnologically exploited by the cosmetic industry. Overall CSMs are striking targets in biotechnology and biomedical research, because of their potential applications in agriculture, industry, and especially in pharmaceuticals.

  11. Inclusion of an ultraviolet radiation transfer component in an urban forest effects model for predicting tree influences on potential below-canopy exposure to UVB radiation

    Treesearch

    Gordon M. Heisler; Richard H. Grant; David J. Nowak; Wei Gao; Daniel E. Crane; Jeffery T. Walton

    2003-01-01

    Evaluating the impact of ultraviolet-B radiation (UVB) on urban populations would be enhanced by improved predictions of the UVB radiation at the level of human activity. This paper reports the status of plans for incorporating a UVB prediction module into an existing Urban Forest Effects (UFORE) model. UFORE currently has modules to quantify urban forest structure,...

  12. Solar Activity, Ultraviolet Radiation and Consequences in Birds in Mexico City, 2001- 2002

    NASA Astrophysics Data System (ADS)

    Valdes, M.; Velasco, V.

    2008-12-01

    Anomalous behavior in commercial and pet birds in Mexico City was reported during 2002 by veterinarians at the Universidad Nacional Autonoma de Mexico. This was attributed to variations in the surrounding luminosity. The solar components, direct, diffuse, global, ultraviolet band A and B, as well as some meteorological parameters, temperature, relative humidity, and precipitation, were then analyzed at the Solar Radiation Laboratory. Although the total annual radiance of the previously mentioned radiation components did not show important changes, ultraviolet Band-B solar radiation did vary significantly. During 2001 the total annual irradiance , 61.05 Hjcm² to 58.32 Hjcm², was 1.6 standard deviations lower than one year later, in 2002 and increased above the mean total annual irradiance, to 65.75 Hjcm², 2.04 standard deviations, giving a total of 3.73 standard deviations for 2001-2002. Since these differences did not show up clearly in the other solar radiation components, daily extra-atmosphere irradiance was analyzed and used to calculate the total annual extra-atmosphere irradiance, which showed a descent for 2001. Our conclusions imply that Ultraviolet Band-B solar radiation is representative of solar activity and has an important impact on commercial activity related with birds.

  13. Photoprotection of human skin beyond ultraviolet radiation.

    PubMed

    Grether-Beck, Susanne; Marini, Alessandra; Jaenicke, Thomas; Krutmann, Jean

    2014-01-01

    Photoprotection of human skin by means of sunscreens or daily skin-care products is traditionally centered around the prevention of acute (e.g. sunburn) and chronic (e.g. skin cancer and photoaging) skin damage that may result from exposure to ultraviolet rays (UVB and UVA). Within the last decade, however, it has been appreciated that wavelengths beyond the ultraviolet spectrum, in particular visible light and infrared radiation, contribute to skin damage in general and photoaging of human skin in particular. As a consequence, attempts have been made to develop skin care/sunscreen products that not only protect against UVB or UVA radiation but provide photoprotection against visible light and infrared radiation as well. In this article, we will briefly review the current knowledge about the mechanisms responsible for visible light/infrared radiation-induced skin damage and then, based on this information, discuss strategies that have been successfully used or may be employed in the future to achieve photoprotection of human skin beyond ultraviolet radiation. In this regard we will particularly focus on the use of topical antioxidants and the challenges that result from the task of showing their efficacy. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  14. Impact of ultraviolet radiation treatments on the physicochemical properties, antioxidants, enzyme activity and microbial load in freshly prepared hand pressed strawberry juice.

    PubMed

    Bhat, Rajeev; Stamminger, Rainer

    2015-07-01

    Freshly prepared, hand-pressed strawberry fruit juice was exposed to ultraviolet radiation (254 nm) at room temperature (25 ℃ ± 1 ℃) for 15, 30 and 60 min with 0 min serving as control. Results revealed decrease in pH, total soluble solids and titratable acidity, while colour parameters (L*, a* and b* values) and clarity of juice (% transmittance) increased significantly. All the results corresponded to exposure time to ultraviolet radiation. Bioactive compounds (total phenolics, ascorbic acid and anthocyanins) decreased along with a recorded reduction in polyphenol oxidase enzyme and 1,1-diphenyl-2-picryl hydrazyl radical scavenging activities, which were again dependent on exposure time. Results on the microbial studies showed significant reduction by 2-log cycles in aerobic plate count as well as in total yeast and mould counts. Though negative results were observed for certain parameters, this is the first time it was endeavoured to demonstrate the impact of ultraviolet radiation radiation on freshly prepared, hand-pressed strawberries juice. © The Author(s) 2014.

  15. Interventions to prevent skin cancer by reducing exposure to ultraviolet radiation: a systematic review.

    PubMed

    Saraiya, Mona; Glanz, Karen; Briss, Peter A; Nichols, Phyllis; White, Cornelia; Das, Debjani; Smith, S Jay; Tannor, Bernice; Hutchinson, Angela B; Wilson, Katherine M; Gandhi, Nisha; Lee, Nancy C; Rimer, Barbara; Coates, Ralph C; Kerner, Jon F; Hiatt, Robert A; Buffler, Patricia; Rochester, Phyllis

    2004-12-01

    The relationship between skin cancer and ultraviolet radiation is well established. Behaviors such as seeking shade, avoiding sun exposure during peak hours of radiation, wearing protective clothing, or some combination of these behaviors can provide protection. Sunscreen use alone is not considered an adequate protection against ultraviolet radiation. This report presents the results of systematic reviews of effectiveness, applicability, other harms or benefits, economic evaluations, and barriers to use of selected interventions to prevent skin cancer by reducing exposure to ultraviolet radiation. The Task Force on Community Preventive Services found that education and policy approaches to increasing sun-protective behaviors were effective when implemented in primary schools and in recreational or tourism settings, but found insufficient evidence to determine effectiveness when implemented in other settings, such as child care centers, secondary schools and colleges, and occupational settings. They also found insufficient evidence to determine the effectiveness of interventions oriented to healthcare settings and providers, media campaigns alone, interventions oriented to parents or caregivers of children, and community-wide multicomponent interventions. The report also provides suggestions for areas for future research.

  16. Solar ultraviolet radiation in a changing climate

    EPA Science Inventory

    The projected large increases in damaging ultraviolet radiation as a result of global emissions of ozone-depleting substances have been forestalled by the success of the Montreal Protocol. New challenges are now arising in relation to climate change. We highlight the complex inte...

  17. PROBABILISTIC RISK ASSESSMENT FOR THE EFFECTS OF SOLAR ULTRAVIOLET RADIATION ON AMPHIBIANS

    EPA Science Inventory

    Several studies have demonstrated that exposure to solar ultraviolet (UV) radiation can cause elevated mortality and an increased prevalence of eye and limb malformations in developing amphibian larvae. From these observations scientists have hypothesized that recent increases in...

  18. ULTRAVIOLET RADIATION AND ARSENIC INTERACTIONS: EFFECTS ON CLADOCERANS

    EPA Science Inventory

    The effects of arsenic and ultraviolet radiation (UV) on cladocerans have been examined separately, however the interaction of these two stresses has not been explored. Potential synergism between these two stresses is possible as arsenic is known to inhibit repair of UV induced ...

  19. The budget of biologically active ultraviolet radiation in the earth-atmosphere system

    NASA Technical Reports Server (NTRS)

    Frederick, John E.; Lubin, Dan

    1988-01-01

    This study applies the concept of a budget to describe the interaction of solar ultraviolet (UV) radiation with the earth-atmosphere system. The wavelength ranges of interest are the biologically relevant UV-B between 280 and 320 nm and the UV-A from 32000 to 400 nm. The Nimbus 7 solar backscattered ultraviolet (SBUV) instrument provides measurements of total column ozone and information concerning cloud cover which, in combination with a simple model of radiation transfer, define the fractions of incident solar irradiance absorbed in the atmosphere, reflected to space, and absorbed at the ground. Results for the month of July quantify the contribution of fractional cloud cover and cloud optical thickness to the radiation budget's three components. Scattering within a thick cloud layer makes the downward radiation field at the cloud base more isotropic than is the case for clear skies. For small solar zenith angles, typical of summer midday conditions, the effective pathlength of this diffuse irradiance through tropospheric ozone is greater than that under clear-sky conditions. The result is an enhanced absorption of UV-B radiation in the troposphere during cloud-covered conditions. Major changes in global cloud cover or cloud optical thicknesses could alter the ultraviolet radiation received by the biosphere by an amount comparable to that predicted for long-term trends in ozone.

  20. Method for extreme ultraviolet lithography

    DOEpatents

    Felter, T. E.; Kubiak, Glenn D.

    1999-01-01

    A method of producing a patterned array of features, in particular, gate apertures, in the size range 0.4-0.05 .mu.m using projection lithography and extreme ultraviolet (EUV) radiation. A high energy laser beam is used to vaporize a target material in order to produce a plasma which in turn, produces extreme ultraviolet radiation of a characteristic wavelength of about 13 nm for lithographic applications. The radiation is transmitted by a series of reflective mirrors to a mask which bears the pattern to be printed. The demagnified focused mask pattern is, in turn, transmitted by means of appropriate optics and in a single exposure, to a substrate coated with photoresists designed to be transparent to EUV radiation and also satisfy conventional processing methods.

  1. Method for extreme ultraviolet lithography

    DOEpatents

    Felter, T. E.; Kubiak, G. D.

    2000-01-01

    A method of producing a patterned array of features, in particular, gate apertures, in the size range 0.4-0.05 .mu.m using projection lithography and extreme ultraviolet (EUV) radiation. A high energy laser beam is used to vaporize a target material in order to produce a plasma which in turn, produces extreme ultraviolet radiation of a characteristic wavelength of about 13 nm for lithographic applications. The radiation is transmitted by a series of reflective mirrors to a mask which bears the pattern to be printed. The demagnified focused mask pattern is, in turn, transmitted by means of appropriate optics and in a single exposure, to a substrate coated with photoresists designed to be transparent to EUV radiation and also satisfy conventional processing methods.

  2. Ocean acidification alters the photosynthetic responses of a coccolithophorid to fluctuating ultraviolet and visible radiation.

    PubMed

    Jin, Peng; Gao, Kunshan; Villafañe, Virginia E; Campbell, Douglas A; Helbling, E Walter

    2013-08-01

    Mixing of seawater subjects phytoplankton to fluctuations in photosynthetically active radiation (400-700 nm) and ultraviolet radiation (UVR; 280-400 nm). These irradiance fluctuations are now superimposed upon ocean acidification and thinning of the upper mixing layer through stratification, which alters mixing regimes. Therefore, we examined the photosynthetic carbon fixation and photochemical performance of a coccolithophore, Gephyrocapsa oceanica, grown under high, future (1,000 μatm) and low, current (390 μatm) CO₂ levels, under regimes of fluctuating irradiances with or without UVR. Under both CO₂ levels, fluctuating irradiances, as compared with constant irradiance, led to lower nonphotochemical quenching and less UVR-induced inhibition of carbon fixation and photosystem II electron transport. The cells grown under high CO₂ showed a lower photosynthetic carbon fixation rate but lower nonphotochemical quenching and less ultraviolet B (280-315 nm)-induced inhibition. Ultraviolet A (315-400 nm) led to less enhancement of the photosynthetic carbon fixation in the high-CO₂-grown cells under fluctuating irradiance. Our data suggest that ocean acidification and fast mixing or fluctuation of solar radiation will act synergistically to lower carbon fixation by G. oceanica, although ocean acidification may decrease ultraviolet B-related photochemical inhibition.

  3. Tea, coffee, and cocoa as ultraviolet radiation protectants for beet armyworm nucleopolyhedrovirus

    USDA-ARS?s Scientific Manuscript database

    The addition of 1% (wt/v) aqueous extracts of cocoa (Theobroma cacao L.) (Malvales: Malvaceae), coffee (Coffea arabica L.) (Gentianales: Rubiaceae), green, and black tea (Camellia sinensis L.) (Ericales: Theaceae) provided excellent ultraviolet (UV) radiation protection for the beet armyworm, Spodo...

  4. Estimated Ultraviolet Radiation Doses in Wetlands in Six National Parks

    EPA Science Inventory

    Ultraviolet radiation (UVR) has been suggested as a potential cause of population declines and increases in malformations in amphibians. This study indicates that the present distributions of amphibians in four western U.S. National Parks are not related to UVR exposure, and sugg...

  5. SIMULATED SOLAR ULTRAVIOLET RADIATION EFFECTS ON 5 SPECIES OF SCLERACTINIAN CORALS

    EPA Science Inventory

    The impact of global climate change factors such as increased temperature and ultraviolet radiation (UVR) on coral bleaching are of continued interest to the USEPA. Coral bleaching occurs when symbiotic zooxanthellae and/or their pigments are depleted in response to stressors suc...

  6. The Growing Public Health Challenges of Exposure to Ultraviolet Radiation From Use of Indoor Tanning Devices in the United States.

    PubMed

    Bowman, Diana M; Lewis, Ryan C; Lee, Maximilian S; Yao, Catherine J

    2015-08-01

    Ultraviolet radiation is recognized as a human carcinogen by the International Agency for Research on Cancer, the world's authority on cancer research. In particular, exposure to ultraviolet radiation can lead to melanoma of the skin, which is the deadliest form of skin cancer in the United States. Yet despite the significant public health burden that is associated with skin cancer in the United States, each year over a million Americans engage in indoor tanning where exposure to artificial ultraviolet radiation occurs. In this article, we argue for an immediate ban on the use of commercial indoor tanning by minors and, based on international precedents, the phasing out of all commercial tanning operations in the United States. We consider the use of indoor tanning devices in the United States, epidemiological data on indoor tanning devices and cancer, regulation of tanning devices, and scientific evidence for increased government intervention. © The Author(s) 2015.

  7. Relativistic frequency upshift to the extreme ultraviolet regime using self-induced oscillatory flying mirrors

    PubMed Central

    Kim, I Jong; Pae, Ki Hong; Kim, Chul Min; Kim, Hyung Taek; Yun, Hyeok; Yun, Sang Jae; Sung, Jae Hee; Lee, Seong Ku; Yoon, Jin Woo; Yu, Tae Jun; Jeong, Tae Moon; Nam, Chang Hee; Lee, Jongmin

    2012-01-01

    Coherent short-wavelength radiation from laser–plasma interactions is of increasing interest in disciplines including ultrafast biomolecular imaging and attosecond physics. Using solid targets instead of atomic gases could enable the generation of coherent extreme ultraviolet radiation with higher energy and more energetic photons. Here we present the generation of extreme ultraviolet radiation through coherent high-harmonic generation from self-induced oscillatory flying mirrors—a new-generation mechanism established in a long underdense plasma on a solid target. Using a 30-fs, 100-TW Ti:sapphire laser, we obtain wavelengths as short as 4.9 nm for an optimized level of amplified spontaneous emission. Particle-in-cell simulations show that oscillatory flying electron nanosheets form in a long underdense plasma, and suggest that the high-harmonic generation is caused by reflection of the laser pulse from electron nanosheets. We expect this extreme ultraviolet radiation to be valuable in realizing a compact X-ray instrument for research in biomolecular imaging and attosecond physics. PMID:23187631

  8. Two ultraviolet radiation datasets that cover China

    NASA Astrophysics Data System (ADS)

    Liu, Hui; Hu, Bo; Wang, Yuesi; Liu, Guangren; Tang, Liqin; Ji, Dongsheng; Bai, Yongfei; Bao, Weikai; Chen, Xin; Chen, Yunming; Ding, Weixin; Han, Xiaozeng; He, Fei; Huang, Hui; Huang, Zhenying; Li, Xinrong; Li, Yan; Liu, Wenzhao; Lin, Luxiang; Ouyang, Zhu; Qin, Boqiang; Shen, Weijun; Shen, Yanjun; Su, Hongxin; Song, Changchun; Sun, Bo; Sun, Song; Wang, Anzhi; Wang, Genxu; Wang, Huimin; Wang, Silong; Wang, Youshao; Wei, Wenxue; Xie, Ping; Xie, Zongqiang; Yan, Xiaoyuan; Zeng, Fanjiang; Zhang, Fawei; Zhang, Yangjian; Zhang, Yiping; Zhao, Chengyi; Zhao, Wenzhi; Zhao, Xueyong; Zhou, Guoyi; Zhu, Bo

    2017-07-01

    Ultraviolet (UV) radiation has significant effects on ecosystems, environments, and human health, as well as atmospheric processes and climate change. Two ultraviolet radiation datasets are described in this paper. One contains hourly observations of UV radiation measured at 40 Chinese Ecosystem Research Network stations from 2005 to 2015. CUV3 broadband radiometers were used to observe the UV radiation, with an accuracy of 5%, which meets the World Meteorology Organization's measurement standards. The extremum method was used to control the quality of the measured datasets. The other dataset contains daily cumulative UV radiation estimates that were calculated using an all-sky estimation model combined with a hybrid model. The reconstructed daily UV radiation data span from 1961 to 2014. The mean absolute bias error and root-mean-square error are smaller than 30% at most stations, and most of the mean bias error values are negative, which indicates underestimation of the UV radiation intensity. These datasets can improve our basic knowledge of the spatial and temporal variations in UV radiation. Additionally, these datasets can be used in studies of potential ozone formation and atmospheric oxidation, as well as simulations of ecological processes.

  9. Pathophysiology of ocular surface squamous neoplasia

    PubMed Central

    Gichuhi, Stephen; Ohnuma, Shin-ichi; Sagoo, Mandeep S.; Burton, Matthew J.

    2014-01-01

    The incidence of ocular surface squamous neoplasia (OSSN) is strongly associated with solar ultraviolet (UV) radiation, HIV and human papilloma virus (HPV). Africa has the highest incidence rates in the world. Most lesions occur at the limbus within the interpalpebral fissure particularly the nasal sector. The nasal limbus receives the highest intensity of sunlight. Limbal epithelial crypts are concentrated nasally and contain niches of limbal epithelial stem cells in the basal layer. It is possible that these are the progenitor cells in OSSN. OSSN arises in the basal epithelial cells spreading towards the surface which resembles the movement of corneo-limbal stem cell progeny before it later invades through the basement membrane below. UV radiation damages DNA producing pyrimidine dimers in the DNA chain. Specific CC → TT base pair dimer transformations of the p53 tumour-suppressor gene occur in OSSN allowing cells with damaged DNA past the G1-S cell cycle checkpoint. UV radiation also causes local and systemic photoimmunosuppression and reactivates latent viruses such as HPV. The E7 proteins of HPV promote proliferation of infected epithelial cells via the retinoblastoma gene while E6 proteins prevent the p53 tumour suppressor gene from effecting cell-cycle arrest of DNA-damaged and infected cells. Immunosuppression from UV radiation, HIV and vitamin A deficiency impairs tumour immune surveillance allowing survival of aberrant cells. Tumour growth and metastases are enhanced by; telomerase reactivation which increases the number of cell divisions a cell can undergo; vascular endothelial growth factor for angiogenesis and matrix metalloproteinases (MMPs) that destroy the intercellular matrix between cells. Despite these potential triggers, the disease is usually unilateral. It is unclear how HPV reaches the conjunctiva. PMID:25447808

  10. Continuous-wave ultraviolet generation at 320 nm by intracavity frequency doubling of red-emitting Praseodymium lasers

    NASA Astrophysics Data System (ADS)

    Richter, A.; Pavel, N.; Heumann, E.; Huber, G.; Parisi, D.; Toncelli, A.; Tonelli, M.; Diening, A.; Seelert, W.

    2006-04-01

    We describe a new approach for the generation of coherent ultraviolet radiation. Continuous-wave ultraviolet light at 320 nm has been obtained by intracavity frequency doubling of red-emitting Praseodymium lasers. Lasing at the 640-nm fundamental wavelength in Pr:LiYF4 and Pr:BaY2F8 was realized by employing an optically pumped semiconductor laser at 480 nm as pump source.Using LiB3O5 as nonlinear medium, ~19 mW of ultraviolet radiation with ~9% optical efficiency with respect to absorbed power was reached for both laser crystals; the visible-to-ultraviolet conversion efficiency was 26% and 35% for Pr:LiYF4 and Pr:BaY2F8, respectively.

  11. Medical Surveillance Monthly Report

    DTIC Science & Technology

    2016-12-01

    sure to ultraviolet radiation is the major risk factor for NMSC, personal pro- tective measures such as wearing proper clothing, decreasing time in...tone and light-colored eyes and hair, and envi- ronmental factors, particularly exposure to solar ultraviolet (UV) radiation .4 In the U.S., the... radiation is well accepted as a risk factor as evidenced by observed patterns or the anatomic distributions of NMSCs, higher rates by latitude, higher

  12. Current challenges in photoprotection.

    PubMed

    Lim, Henry W; Arellano-Mendoza, Maria-Ivonne; Stengel, Fernando

    2017-03-01

    Electromagnetic radiation in the ultraviolet, visible, and infrared ranges all produce biologic effects. Ultraviolet filters are the most well-studied photoprotective measure for the adverse effects of ultraviolet radiation. Because of the reported endocrinologic effects of oxybenzone in animal studies, its effects on coral reefs, and its photocontact allergy potential, its use has been minimized in many countries worldwide. New developments in topical antioxidants and oral and subcutaneous agents (eg, Polypodium leucotomos extract, afamelanotide, nicotinamide) with photoprotective and antiphotocarcinogenic properties could potentially provide addition modalities for protection against the effects of visible light and infrared radiation. Copyright © 2016 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

  13. Results of the examination of LDEF polyurethane thermal control coatings

    NASA Technical Reports Server (NTRS)

    Golden, Johnny L.

    1994-01-01

    This report summarizes the condition of polyurethane thermal control coatings subjected to 69 months of low earth orbit (LEO) exposure on the Long Duration Exposure Facility (LDEF) mission. Specimens representing all environmental aspects obtainable by LDEF were analyzed. Widely varying changes in the thermo-optical and mechanical properties of these materials were observed, depending on atomic oxygen and ultraviolet radiation fluences. High atomic oxygen fluences, regardless of ultraviolet radiation exposure levels, resulted in near original optical properties for these coatings but with a degradation in their mechanical condition. A trend in solar absorptance increase with ultraviolet radiation fluence was observed. Contamination, though observed, exhibited minimal effects.

  14. Biological Effects of Sunlight, Ultraviolet Radiation, Visible Light, Infrared Radiation and Vitamin D for Health.

    PubMed

    Holick, Michael F

    2016-03-01

    Humans evolved in sunlight and had depended on sunlight for its life giving properties that was appreciated by our early ancestors. However, for more than 40 years the lay press and various medical and dermatology associations have denounced sun exposure because of its association with increased risk for skin cancer. The goal of this review is to put into perspective the many health benefits that have been associated with exposure to sunlight, ultraviolet A (UVA) ultraviolet B (UVB), visible and infrared radiation. Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

  15. Fernblock (Polypodium leucotomos Extract): Molecular Mechanisms and Pleiotropic Effects in Light-Related Skin Conditions, Photoaging and Skin Cancers, a Review

    PubMed Central

    Parrado, Concepcion; Mascaraque, Marta; Gilaberte, Yolanda; Juarranz, Angeles; Gonzalez, Salvador

    2016-01-01

    Healthier life styles include increased outdoors time practicing sports and walking. This means increased exposure to the sun, leading to higher risk of sunburn, photoaging and skin cancer. In addition to topical barrier products, oral supplementations of various botanicals endowed with antioxidant activity are emerging as novel method of photoprotection. Polypodium leucotomos extract (PL, commercial name Fernblock®, IFC Group, Spain) is a powerful antioxidant due to its high content of phenolic compounds. PL is administered orally, with proven safety, and it can also be used topically. Its mechanisms include inhibition of the generation and release of reactive oxygen species (ROS) by ultraviolet (UV) light. It also prevents UV- and ROS-induced DNA damage with inhibition of AP1 and NF-κB and protection of natural antioxidant enzyme systems. At the cellular level, PL decreases cellular apoptosis and necrosis mediated UV and inhibits abnormal extracellular matrix remodeling. PL reduces inflammation, prevents immunosuppression, activates tumor suppressor p53 and inhibits UV-induced cyclooxygenase-2 (COX-2) enzyme expression. In agreement with increased p53 activity, PL decreased UV radiation-induced cell proliferation. PL also prevents common deletions mitochondrial DNA damage induced by UVA, and MMP-1 expression induced Visible Light and Infrared Radiation. These cellular and molecular effects are reflected in inhibitions of carcinogenesis and photoaging. PMID:27367679

  16. Fernblock (Polypodium leucotomos Extract): Molecular Mechanisms and Pleiotropic Effects in Light-Related Skin Conditions, Photoaging and Skin Cancers, a Review.

    PubMed

    Parrado, Concepcion; Mascaraque, Marta; Gilaberte, Yolanda; Juarranz, Angeles; Gonzalez, Salvador

    2016-06-29

    Healthier life styles include increased outdoors time practicing sports and walking. This means increased exposure to the sun, leading to higher risk of sunburn, photoaging and skin cancer. In addition to topical barrier products, oral supplementations of various botanicals endowed with antioxidant activity are emerging as novel method of photoprotection. Polypodium leucotomos extract (PL, commercial name Fernblock(®), IFC Group, Spain) is a powerful antioxidant due to its high content of phenolic compounds. PL is administered orally, with proven safety, and it can also be used topically. Its mechanisms include inhibition of the generation and release of reactive oxygen species (ROS) by ultraviolet (UV) light. It also prevents UV- and ROS-induced DNA damage with inhibition of AP1 and NF-κB and protection of natural antioxidant enzyme systems. At the cellular level, PL decreases cellular apoptosis and necrosis mediated UV and inhibits abnormal extracellular matrix remodeling. PL reduces inflammation, prevents immunosuppression, activates tumor suppressor p53 and inhibits UV-induced cyclooxygenase-2 (COX-2) enzyme expression. In agreement with increased p53 activity, PL decreased UV radiation-induced cell proliferation. PL also prevents common deletions mitochondrial DNA damage induced by UVA, and MMP-1 expression induced Visible Light and Infrared Radiation. These cellular and molecular effects are reflected in inhibitions of carcinogenesis and photoaging.

  17. Ultra-violet radiation is responsible for the differences in global epidemiology of chickenpox and the evolution of varicella-zoster virus as man migrated out of Africa

    PubMed Central

    2011-01-01

    Background Of the eight human herpes viruses, varicella-zoster virus, which causes chickenpox and zoster, has a unique epidemiology. Primary infection is much less common in children in the tropics compared with temperate areas. This results in increased adult susceptibility causing outbreaks, for example in health-care workers migrating from tropical to temperate countries. The recent demonstration that there are different genotypes of varicella-zoster virus and their geographic segregation into tropical and temperate areas suggests a distinct, yet previously unconsidered climatic factor may be responsible for both the clinical and molecular epidemiological features of this virus infection. Presentation of the hypothesis Unlike other human herpes viruses, varicella-zoster virus does not require intimate contact for infection to occur indicating that transmission may be interrupted by a geographically restricted climatic factor. The factor with the largest difference between tropical and temperate zones is ultra-violet radiation. This could reduce the infectiousness of chickenpox cases by inactivating virus in vesicles, before or after rupture. This would explain decreased transmissibility in the tropics and why the peak chickenpox incidence in temperate zones occurs during winter and spring, when ultra-violet radiation is at its lowest. The evolution of geographically restricted genotypes is also explained by ultra-violet radiation driving natural selection of different virus genotypes with varying degrees of resistance to inactivation, tropical genotypes being the most resistant. Consequently, temperate viruses should be more sensitive to its effects. This is supported by the observation that temperate genotypes are found in the tropics only in specific circumstances, namely where ultra-violet radiation has either been excluded or significantly reduced in intensity. Testing the Hypothesis The hypothesis is testable by exposing different virus genotypes to ultra-violet radiation and quantifying virus survival by plaque forming units or quantitative mRNA RT-PCR. Implications of the hypothesis The ancestral varicella-zoster virus, most probably a tropical genotype, co-migrated with man as he left Africa approximately 200,000 years ago. For this virus to have lost the selective advantage of resistance to ultra-violet radiation, the hypothesis would predict that the temperate, ultra-violet sensitive virus should have acquired another selective advantage as an evolutionary trade-off. One obvious advantage could be an increased reactivation rate as zoster to set up more rounds of chickenpox transmission. If this were so, the mechanism responsible for resistance to ultra-violet radiation might also be involved in reactivation and latency. This could then provide the first insight into a genetic correlate of the survival strategy of this virus. PMID:21513563

  18. MECHANISMS OF PLANT RESISTANCE TO INCREASED SOLAR ULTRAVIOLET-B RADIATION

    EPA Science Inventory

    Since the major conclusions of the project are being disseminated via the scientific literature, the final report consists of a compilation of 11 articles and manuscripts on the effects of ultraviolet-B radiation (UVB) on soybean growth and yield, stress interactions with UVB, an...

  19. ASSESSMENT OF THE RISK OF SOLAR ULTRAVIOLET RADIATION TO AMPHIBIANS: III. PREDICTION OF IMPACTS IN SELECTED NORTHERN MIDWESTERN WETLANDS

    EPA Science Inventory

    The deleterious effects of solar ultraviolet radiation, especially the UV-B portion of sunlight, have been hypothesized to reduce survival, increase the frequency of malformations, and contribute to the apparent worldwide decline of many amphibian species.

  20. SOLAR ULTRAVIOLET RADIATION AND AQUATIC CARBON, NITROGEN, SULFUR AND METALS CYCLES

    EPA Science Inventory

    Solar ultraviolet radiation (290-400 nm) has a wide-ranging impact on biological and chemical processes that affect the cycling of elements in aquatic environments. This chapter uses recent field and laboratory observations along with models to assess these impacts on carbon, nit...

  1. Coordinated Studies of Ultraviolet Radiation and Amphibians in Lentic Wetland Habitats

    EPA Science Inventory

    Ultraviolet radiation (UVR) has been suggested as a potential cause of population declines and increases in malformations in amphibians. This study indicates that the present distributions of amphibians in four western U.S. National Parks are not related to UVR exposure, and sugg...

  2. ULTRAVIOLET RADIATION DOSE AND AMPHIBIAN DISTRIBUTIONS IN NATIONAL PARKS

    EPA Science Inventory

    Ultraviolet Radiation Dose and Amphibian Distributions in National Parks. Diamond, S. A., Detenbeck, N. E., USEPA, Duluth, MN, USA, Bradford, D. F., USEPA, Las Vegas, NV, USA, Trenham, P. C., University of California, Davis, CA., USA, Adams, M. J., Corn, P. S., Hossack, B., USGS,...

  3. Ultraviolet Radiation Dose National Standard of México

    NASA Astrophysics Data System (ADS)

    Cardoso, R.; Rosas, E.

    2006-09-01

    We present the Ultraviolet (UV) Radiation Dose National Standard for México. The establishment of this measurement reference at Centro Nacional de Metrología (CENAM) eliminates the need of contacting foreign suppliers in the search for traceability towards the SI units when calibrating instruments at 365 nm. Further more, the UV Radiation Dose National Standard constitutes a highly accurate and reliable source for the UV radiation dose measurements performed in medical and cosmetic treatments as in the the food and pharmaceutics disinfection processes, among other.

  4. Universal EUV in-band intensity detector

    DOEpatents

    Berger, Kurt W.

    2004-08-24

    Extreme ultraviolet light is detected using a universal in-band detector for detecting extreme ultraviolet radiation that includes: (a) an EUV sensitive photodiode having a diode active area that generates a current responsive to EUV radiation; (b) one or more mirrors that reflects EUV radiation having a defined wavelength(s) to the diode active area; and (c) a mask defining a pinhole that is positioned above the diode active area, wherein EUV radiation passing through the pinhole is restricted substantially to illuminating the diode active area.

  5. Effects of ultraviolet radiation, visible light, and infrared radiation on erythema and pigmentation: a review.

    PubMed

    Sklar, Lindsay R; Almutawa, Fahad; Lim, Henry W; Hamzavi, Iltefat

    2013-01-01

    The effects of ultraviolet radiation, visible light, and infrared radiation on cutaneous erythema, immediate pigment darkening, persistent pigment darkening, and delayed tanning are affected by a variety of factors. Some of these factors include the depth of cutaneous penetration of the specific wavelength, the individual skin type, and the absorption spectra of the different chromophores in the skin. UVB is an effective spectrum to induce erythema, which is followed by delayed tanning. UVA induces immediate pigment darkening, persistent pigment darkening, and delayed tanning. At high doses, UVA (primarily UVA2) can also induce erythema in individuals with skin types I-II. Visible light has been shown to induce erythema and a tanning response in dark skin, but not in fair skinned individuals. Infrared radiation produces erythema, which is probably a thermal effect. In this article we reviewed the available literature on the effects of ultraviolet radiation, visible light, and infrared radiation on the skin in regards to erythema and pigmentation. Much remains to be learned on the cutaneous effects of visible light and infrared radiation.

  6. Method and apparatus for producing durationally short ultraviolet or X-ray laser pulses

    DOEpatents

    MacGowan, Brian J.; Matthews, Dennis L.; Trebes, James E.

    1988-01-01

    A method and apparatus is disclosed for producing ultraviolet or X-ray laser pulses of short duration (32). An ultraviolet or X-ray laser pulse of long duration (12) is progressively refracted, across the surface of an opaque barrier (28), by a streaming plasma (22) that is produced by illuminating a solid target (16, 18) with a pulse of conventional line focused high power laser radiation (20). The short pulse of ultraviolet or X-ray laser radiation (32), which may be amplified to high power (40, 42), is separated out by passage through a slit aperture (30) in the opaque barrier (28).

  7. Ultraviolet Radiation: Human Exposure and Health Risks.

    ERIC Educational Resources Information Center

    Tenkate, Thomas D.

    1998-01-01

    Provides an overview of human exposure to ultraviolet radiation and associated health effects as well as risk estimates for acute and chronic conditions resulting from such exposure. Demonstrates substantial reductions in health risk that can be achieved through preventive actions. Also includes a risk assessment model for skin cancer. Contains 36…

  8. Some Thoughts on Teaching about Ultraviolet Radiation

    ERIC Educational Resources Information Center

    Thumm, Walter

    1975-01-01

    Describes the major obstacles in the study of ultraviolet radiation (UV). Presents the beneficial aspects of UV such as vitamin O production, sterilization, clinical treatment of diseases and wounds, and the marking of patients for radiotherapy. Warns of the dangers of UV exposure such as skin cancer and early aging. (GS)

  9. INFLUENCE OF FLORAL OPTICAL PROPERTIES ON THE ULTRAVIOLET RADIATION ENVIRONMENT OF POLLEN

    EPA Science Inventory

    Pollen in unopened flowers of most species is totally screened from solar ultraviolet-B radiation by imbricated petals that are largely opaque to UV-B. Following flower opening but before another dehiscence, the anther walls of the species investigated filter out over 98% of the ...

  10. Interactions of Changing Solar Ultraviolet Radiation and Climate with Light Induced Chemical Reactions in Aquatic Environments

    EPA Science Inventory

    Changes in the ozone layer over the past two decades have resulted in increases in solar ultraviolet radiation that reach the surface of North American aquatic environments. Concurrent changes in atmospheric CO2 are resulting in changes in stratification and precipitation that ar...

  11. EFFECT OF ARSENICALS ON ULTRAVIOLET-RADIATION-INDUCED GROWTH ARREST AND RELATED SIGNALING EVENTS IN HUMAN KERATINOCYTES

    EPA Science Inventory

    The molecular mechanisms mediating arsenic-induced carcinogenesis are not well understood. The role of confounding factors such as ultraviolet radiation (UV), add another level of complexity to the study of arsenic carcinogenesis and the cancer risk assessment to humans. We hypot...

  12. QUANTIFYING ULTRAVIOLET RADIATION DOSE RELATIVE TO WETLAND HABITAT VARIABLES FOR THE ASSESSMENT OF RISK TO AMPHIBIANS

    EPA Science Inventory

    Ultraviolet B radiation (UV-B) has increased globally over the last several decades due to reduction of stratospheric ozone. UV-B may also increase when climate change alters cloud cover, rainfall, and distributions of vegetation. In aquatic systems, these factors can also intera...

  13. REPORT ON GEOGRAPHIC AND SEASONAL VARIABILITY OF UV AFFECTING HUMAN AND ECOLOGICAL HEALTH

    EPA Science Inventory

    This report takes a look at how effects of ultraviolet radiation changes based on season and location. The data collected by EPA's network of Brewer Spectrophotometer devices was analyzed to determine trends in the flux of ultraviolet radiation at the different Brewer sites acro...

  14. Effects of near ultraviolet and green radiations on plant growth

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Klein, R.M.; Edsall, P.C.; Gentile, A.C.

    Selective removal of near ultraviolet and green wavelengths from white light permitted enhanced growth of marigold, tomato, corn, and Impatiens plants, Chlamydomonas cells and the mycelium of Sordaria. Additions of near ultraviolet and green radiations caused repressions in the growth of marigold and Sordaria. These wavelengths do not alter the oxidative mechanisms of mitochondria, intact algal cells or marigold leaf tissues. The capacity for chlorophyll and carotenoid synthesis by Euglena cells was unaffected by these wavelengths. 23 references, 2 figures, 4 tables.

  15. Disinfection of Airborne Organisms by Ultraviolet-C Radiation and Sunlight

    DTIC Science & Technology

    2012-07-01

    organisms deposited on surfaces, suspended in water , and contaminating food, all of which have been discussed elsewhere (Block, 2001). In contrast, the... water . Therefore, the primary means for organism inactivation in aerosols is ultraviolet (UV) radiation. Radiation from the sunlight is used as a...cortex is essential for reduction of the water content in the spore core and formation of a dormant spore. The cortex is degraded in spore

  16. Cloud effects on middle ultraviolet global radiation

    NASA Technical Reports Server (NTRS)

    Borkowski, J.; Chai, A.-T.; Mo, T.; Green, A. E. O.

    1977-01-01

    An Eppley radiometer and a Robertson-Berger sunburn meter are employed along with an all-sky camera setup to study cloud effects on middle ultraviolet global radiation at the ground level. Semiempirical equations to allow for cloud effects presented in previous work are compared with the experimental data. The study suggests a means of defining eigenvectors of cloud patterns and correlating them with the radiation at the ground level.

  17. How does solar ultraviolet-B radiation improve drought tolerance of silver birch (Betula pendula Roth.) seedlings?

    PubMed

    Robson, T Matthew; Hartikainen, Saara M; Aphalo, Pedro J

    2015-05-01

    We hypothesized that solar ultraviolet (UV) radiation would protect silver birch seedlings from the detrimental effects of water stress through a coordinated suite of trait responses, including morphological acclimation, improved control of water loss through gas exchange and hydraulic sufficiency. To better understand how this synergetic interaction works, plants were grown in an experiment under nine treatment combinations attenuating ultraviolet-A and ultraviolet-B (UVB) from solar radiation together with differential watering to create water-deficit conditions. In seedlings under water deficit, UV attenuation reduced height growth, leaf production and leaf length compared with seedlings receiving the full spectrum of solar radiation, whereas the growth and morphology of well-watered seedlings was largely unaffected by UV attenuation. There was an interactive effect of the treatment combination on water relations, which was more apparent as a change in the water potential at which leaves wilted or plants died than through differences in gas exchange. This suggests that changes occur in the cell wall elastic modulus or accumulation of osmolites in cells under UVB. Overall, the strong negative effects of water deficit are partially ameliorated by solar UV radiation, whereas well-watered silver birch seedlings are slightly disadvantaged by the solar UV radiation they receive. © 2014 John Wiley & Sons Ltd.

  18. Ultraviolet laser beam monitor using radiation responsive crystals

    DOEpatents

    McCann, Michael P.; Chen, Chung H.

    1988-01-01

    An apparatus and method for monitoring an ultraviolet laser beam includes disposing in the path of an ultraviolet laser beam a substantially transparent crystal that will produce a color pattern in response to ultraviolet radiation. The crystal is exposed to the ultraviolet laser beam and a color pattern is produced within the crystal corresponding to the laser beam intensity distribution therein. The crystal is then exposed to visible light, and the color pattern is observed by means of the visible light to determine the characteristics of the laser beam that passed through crystal. In this manner, a perpendicular cross sectional intensity profile and a longitudinal intensity profile of the ultraviolet laser beam may be determined. The observation of the color pattern may be made with forward or back scattered light and may be made with the naked eye or with optical systems such as microscopes and television cameras.

  19. 21 CFR 878.4635 - Ultraviolet lamp for tanning.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Ultraviolet lamp for tanning. 878.4635 Section 878... tanning. (a) Identification. An ultraviolet lamp for tanning is a device that is a lamp (including a fixture) intended to provide ultraviolet radiation to tan the skin. See § 1040.20 of this chapter. (b...

  20. Motility and gravitactic orientation of the flagellate, Euglena gracilis, impaired by artificial and solar UV-B radiation.

    PubMed

    Hader, D P; Liu, S M

    1990-09-01

    The effects of ultraviolet radiation on the gravitactic orientation of the freshwater flagellate, Euglena gracilis, were determined by a real time image analysis system. Both artificial UV radiation and solar radiation in a temperature-controlled growth chamber were employed. Histograms of gravitaxis showed that the degree of orientation decreased with increasing exposure time; this can be quantified using the Rayleigh test and upper quadrant summation. The effects of artificial UV radiation on the orientation are considerably stronger than those of solar radiation, probably because the radiation source emits higher fluence rates below 300 nm than found in solar radiation. The effects of monochromatic ultraviolet radiation on motility have been determined, and an action spectrum has been calculated.

  1. Ocean Acidification Alters the Photosynthetic Responses of a Coccolithophorid to Fluctuating Ultraviolet and Visible Radiation1[OPEN

    PubMed Central

    Jin, Peng; Gao, Kunshan; Villafañe, Virginia E.; Campbell, Douglas A.; Helbling, E. Walter

    2013-01-01

    Mixing of seawater subjects phytoplankton to fluctuations in photosynthetically active radiation (400–700 nm) and ultraviolet radiation (UVR; 280–400 nm). These irradiance fluctuations are now superimposed upon ocean acidification and thinning of the upper mixing layer through stratification, which alters mixing regimes. Therefore, we examined the photosynthetic carbon fixation and photochemical performance of a coccolithophore, Gephyrocapsa oceanica, grown under high, future (1,000 μatm) and low, current (390 μatm) CO2 levels, under regimes of fluctuating irradiances with or without UVR. Under both CO2 levels, fluctuating irradiances, as compared with constant irradiance, led to lower nonphotochemical quenching and less UVR-induced inhibition of carbon fixation and photosystem II electron transport. The cells grown under high CO2 showed a lower photosynthetic carbon fixation rate but lower nonphotochemical quenching and less ultraviolet B (280–315 nm)-induced inhibition. Ultraviolet A (315–400 nm) led to less enhancement of the photosynthetic carbon fixation in the high-CO2-grown cells under fluctuating irradiance. Our data suggest that ocean acidification and fast mixing or fluctuation of solar radiation will act synergistically to lower carbon fixation by G. oceanica, although ocean acidification may decrease ultraviolet B-related photochemical inhibition. PMID:23749851

  2. Bioactive grape proanthocyanidins enhance immune reactivity in UV-irradiated skin through functional activation of dendritic cells in mice.

    PubMed

    Vaid, Mudit; Singh, Tripti; Prasad, Ram; Elmets, Craig A; Xu, Hui; Katiyar, Santosh K

    2013-03-01

    Ultraviolet (UV) radiation-induced immunosuppression has been implicated in skin carcinogenesis. Grape seed proanthocyanidins (GSPs) have anti-skin carcinogenic effects in mice and GSPs-fed mice exhibit a reduction in UV-induced suppression of allergic contact hypersensitivity (CHS), a prototypic T-cell-mediated response. Here, we report that dietary GSPs did not inhibit UVB-induced suppression of CHS in xeroderma pigmentosum complementation group A (XPA)-deficient mice, which lack nucleotide excision repair mechanisms. GSPs enhanced repair of UVB-induced DNA damage (cyclobutane pyrimidine dimers) in wild-type, but not XPA-deficient, dendritic cells (DC). Co-culture of CD4(+) T cells with DCs from UVB-irradiated wild-type mice resulted in suppression of T-cell proliferation and secretion of T-helper (TH) 1-type cytokines that was ameliorated when the DCs were obtained from GSP-fed mice, whereas DCs obtained from GSP-fed XPA-KO mice failed to restore T-cell proliferation. In adoptive transfer experiments, donor DCs were positively selected from the draining lymph nodes of UVB-exposed donor mice that were sensitized to 2,4,-dinitrofluorobenzene were transferred into naïve recipient mice and the CHS response assessed. Naïve recipients that received DCs from UVB-exposed wild-type donors that had been fed GSPs exhibited a full CHS response, whereas no significant CHS was observed in mice that received DCs from XPA-KO mice fed GSPs. These results suggest that GSPs prevent UVB-induced immunosuppression through DNA repair-dependent functional activation of dendritic cells in mice. Cancer Prev Res; 6(3); 242-52. ©2013 AACR. ©2013 AACR.

  3. Protective mechanisms and acclimation to solar ultraviolet-B radiation in Oenothera stricta

    NASA Technical Reports Server (NTRS)

    Robberecht, R.; Caldwell, M. M.

    1981-01-01

    Plant adaptations ameliorating or repairing the damaging effects of ultraviolet-B (UV-B) radiation on plant tissue were investigated. The degree of phenotype plasticity in UV protective mechanisms and acclimation in relation to the natural solar UV-B radiation flux and in an enhanced UV-B irradiance environment was also examined. Mechanisms by which plants avoid radiation, adaptations altering the path of radiation incident on the leaf, and repair processes were considered. Attenuation of UV-B by tissues, UV-B irradiation into the leaf, and the effects of UV-B on photosynthesis were investigated.

  4. Estimated Environmental Exposures for MISSE-7B

    NASA Technical Reports Server (NTRS)

    Finckenor, Miria M.; Moore, Chip; Norwood, Joseph K.; Henrie, Ben; DeGroh, Kim

    2012-01-01

    This paper details the 18-month environmental exposure for Materials International Space Station Experiment 7B (MISSE-7B) ram and wake sides. This includes atomic oxygen, ultraviolet radiation, particulate radiation, thermal cycling, meteoroid/space debris impacts, and observed contamination. Atomic oxygen fluence was determined by measured mass and thickness loss of polymers of known reactivity. Diodes sensitive to ultraviolet light actively measured solar radiation incident on the experiment. Comparisons to earlier MISSE flights are discussed.

  5. DISTRIBUTION PATTERNS OF LENTIC-BREEDING AMPHIBIANS IN RELATION OF ULTRAVIOLET RADIATION EXPOSURE IN WESTERN NORTH AMERICA

    EPA Science Inventory

    An increase in ultraviolet (UV-B) radiation has been posited to be a potential factor in the decline of some amphibian population...Much more work is still needed to determine whether UV-B, either alone or in concert with other factors, is causing widespread population losses in ...

  6. Modeling TiO2 nanoparticle phototoxicity: The importance of chemical concentration, ultraviolet radiation intensity, and time

    EPA Science Inventory

    Toxicity of TiO2 nanoparticles (nano-TiO2) to aquatic organisms can be greatly increased upon the exposure to ultraviolet radiation (UV). This phenomenon has received some attention for pelagic species, however, investigations of nano-TiO2 phototoxicity in benthic organisms are s...

  7. Experimental Determination of Ultraviolet Radiation Protection of Common Materials

    ERIC Educational Resources Information Center

    Tavares, Susana C. A.; da Silva, Joaquim C. G. Esteves; Paiva, Joao

    2007-01-01

    Aiming at a better understanding of the problems associated with the depletion of the ozone layer, we propose several experiments to be performed by students of different levels: secondary and first-year undergraduate students. The oxidation of iodide induced by ultraviolet (UV) radiation, generated by a mercury lamp, is used as an indicator for…

  8. Inactivation of Staphylococcus saprophyticus in chicken meat and exudate using high pressure processing, gamma radiation, and ultraviolet light

    USDA-ARS?s Scientific Manuscript database

    Stapylococcus saprophyticus is a common contaminant in foods and causes urinary tract infections in humans. Three nonthermal food safety intervention technologies used to improve the safety foods include high pressure processing (HPP), ionizing (gamma) radiation (GR), and ultraviolet light (UV-C). A...

  9. 21 CFR 179.39 - Ultraviolet radiation for the processing and treatment of food.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 3 2013-04-01 2013-04-01 false Ultraviolet radiation for the processing and treatment of food. 179.39 Section 179.39 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) IRRADIATION IN THE PRODUCTION...

  10. 21 CFR 179.39 - Ultraviolet radiation for the processing and treatment of food.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Ultraviolet radiation for the processing and treatment of food. 179.39 Section 179.39 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) IRRADIATION IN THE PRODUCTION...

  11. 21 CFR 179.39 - Ultraviolet radiation for the processing and treatment of food.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 3 2011-04-01 2011-04-01 false Ultraviolet radiation for the processing and treatment of food. 179.39 Section 179.39 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) IRRADIATION IN THE PRODUCTION...

  12. 21 CFR 179.39 - Ultraviolet radiation for the processing and treatment of food.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 3 2014-04-01 2014-04-01 false Ultraviolet radiation for the processing and treatment of food. 179.39 Section 179.39 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) IRRADIATION IN THE PRODUCTION, PROCESSING AND HANDLING OF FOOD...

  13. 21 CFR 179.39 - Ultraviolet radiation for the processing and treatment of food.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 3 2012-04-01 2012-04-01 false Ultraviolet radiation for the processing and treatment of food. 179.39 Section 179.39 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) IRRADIATION IN THE PRODUCTION...

  14. Metagenomic insights into ultraviolet disinfection effects on antibiotic resistome in biologically treated wastewater.

    PubMed

    Hu, Qing; Zhang, Xu-Xiang; Jia, Shuyu; Huang, Kailong; Tang, Junying; Shi, Peng; Ye, Lin; Ren, Hongqiang

    2016-09-15

    High-throughput sequencing-based metagenomic approaches were used to comprehensively investigate ultraviolet effects on the microbial community structure, and diversity and abundance of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) in biologically treated wastewater. After ultraviolet radiation, some dominant genera, like Aeromonas and Halomonas, in the wastewater almost disappeared, while the relative abundance of some minor genera including Pseudomonas and Bacillus increased dozens of times. Metagenomic analysis showed that 159 ARGs within 14 types were detectable in the samples, and the radiation at 500 mJ/cm(2) obviously increased their total relative abundance from 31.68 ppm to 190.78 ppm, which was supported by quantitative real time PCR. As the dominant persistent ARGs, multidrug resistance genes carried by Pseudomonas and bacitracin resistance gene bacA carried by Bacillus mainly contributed to the ARGs abundance increase. Bacterial community shift and MGEs replication induced by the radiation might drive the resistome alteration. The findings may shed new light on the mechanism behind the ultraviolet radiation effects on antibiotic resistance in wastewater. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Local brain heavy ion irradiation induced Immunosuppression

    NASA Astrophysics Data System (ADS)

    Lei, Runhong; Deng, Yulin; Huiyang Zhu, Bitlife.; Zhao, Tuo; Wang, Hailong; Yu, Yingqi; Ma, Hong; Wang, Xiao; Zhuang, Fengyuan; Qing, Hong

    Purpose: To investigate the long term effect of acute local brain heavy ion irradiation on the peripheral immune system in rat model. Methodology: Only the brain of adult male Wistar rats were radiated by heavy ions at the dose of 15 Gy. One, two and three months after irradiation, thymus and spleen were analyzed by four ways. Tunel assay was performed to evaluate the percentage of apoptotic cells in thymus and spleen, level of Inflammatory cytokines (IL-2, IL-6, SSAO, and TNF-α) was detected by ELISA assay, the differentiation of thymus T lymphocyte subsets were measured by flow cytometry and the relative expression levels of genes related to thymus immune cell development were measured by using quantitative real-time PCR. Results: Thymus and spleen showed significant atrophy from one month to three months after irradiation. A high level of apoptosis in thymus and spleen were obtained and the latter was more vulnerable, also, high level of inflammatory cytokines were found. Genes (c-kit, Rag1, Rag2 and Sca1) related to thymus lymphocytes’ development were down-regulated. Conclusion: Local area radiation in the rat brain would cause the immunosuppression, especially, the losing of cell-mediated immune functions. In this model, radiation caused inflammation and then induced apoptosis of cells in the immune organs, which contributed to immunosuppression.

  16. Elastomeric Seal Performance after Terrestrial Ultraviolet Radiation Exposure

    NASA Technical Reports Server (NTRS)

    Daniels, Christopher C.; Oravec, Heather A.; Mather, Janice L.; Taylor, Shawn C.; Dunlap, Patrick H.

    2015-01-01

    Ultraviolet radiation was evaluated to determine its negative effects on the performance of elastomeric gas pressure seals. The leak rates of the silicone elastomer S0383-70 O-ring test articles were used to quantify the degradation of the seals after exposure to vacuum-ultraviolet and/or middle-to-near-ultraviolet wavelength radiation. Three groups of seals were exposed in terrestrial facilities to 115-165 nm wavelength radiation, 230-500 nm wavelength radiation, or both spectrums, for an orbital spaceflight equivalent of 125 hours. The leak rates of the silicone elastomer S0383-70 seals were quantified and compared to samples that received no radiation. Each lot contained six samples and statistical t-tests were used to determine the separate and combined influences of exposure to the two wavelength ranges. A comparison of the mean leak rates of samples exposed to 115-165 nm wavelength radiation to the control specimens showed no difference, suggesting that spectrum was not damaging. The 230-500 nm wavelength appeared to be damaging, as the mean leak rates of the specimens exposed to that range of wavelengths, and those exposed to the combined 115-165 nm and 230-500 nm spectrums, were significantly different from the leak rates of the control specimens. Most importantly, the test articles exposed to both wavelength spectrums exhibited mean leak rates two orders of magnitude larger than any other exposed specimens, which suggested that both wavelength spectrums are important when simulating the orbital environment.

  17. EFFECTS OF ULTRAVIOLET RADIATION (UVR) ON THE RESPIRATORY ALLERGIC RESPONSES OF BALB/C MICE TO A FUNGAL ALLERGEN

    EPA Science Inventory

    EFFECTS OF ULTRAVIOLET RADIATION (UVR) ON THE RESPIRATORY ALLERGIC RESPONSES OF BALB/C MICE TO A FUNGAL ALLERGEN. M D W Ward, D M Sailstad, D L Andrews, E H Boykin, and MJ K Selgrade. National Health and Environmental Effects Research Laboratory, Office of Research and Developmen...

  18. ROLE OF THE EGG JELLY COAT IN PROTECTING HYLA REGILLA AND BUFO CANORUS EMBRYOS FROM ULTRAVIOLET B RADIATION DURING DEVELOPMENT

    EPA Science Inventory

    Previous studies have suggested that Ultraviolet B (UVB) radiation may play a role in amphibian population declines. Some of these studies also indicate that egg hatching success is unaltered in some species of anurans as a result of UVB exposure. It has been proposed that the eg...

  19. Evaluation of materials during outdoor testing using a computer-controlled test apparatus

    Treesearch

    R. Sam Williams; Steven Lacher; Corey Halpin; Christopher White

    2006-01-01

    Ultraviolet radiation, moisture, heat, and cyclic fatigue are some of the stressors that cause materials to degrade outdoors. Considerable research has addressed the effects of ultraviolet radiation and moisture on the rate of this degradation. An often overlooked stressor on materials, during outdoor testing, is the cyclic fatigue. Cyclic fatigue is caused by self-...

  20. EFFECTS OF ULTRAVIOLET-B IRRADIANCE IN SOYBEAN. 6. INFLUENCE OF PHOSPHORUS NUTRITION ON GROWTH AND FLAVONIID CONTENT

    EPA Science Inventory

    Soybeans Glycine max Essex were hydroponically grown in a greenhouse at 2 levels of ultraviolet-B(UV-B) radiation and 4 levels of P. Plants were grown in each treatment combination to the complete expansion of the 4th trifoliolate leaf. UV-B radiation and reduced P supply general...

  1. INTEGRATED HUMAN AND ECOLOIGCAL RISK ASSESSMENT: A CASE STUDY OF ULTRAVIOLET RADIATION EFFECTS ON AMPHIBIANS, CORAL, HUMANS, AND OCEANIC PRIMARY PRODUCTIVITY

    EPA Science Inventory

    Ultraviolet radiation (UVR) is a naturally occurring stressor to most forms of life. The sole relevant source of this stressor is the sun. The Earth's stratospheric ozone layer reduces the amount of UVR that reaches the Earth's surface. The potential for continued depletion of th...

  2. Altmetric: 165More detailArticle | OPENClimate change-induced increases in precipitation are reducing the potential for solar ultraviolet radiation to inactivate pathogens in surface waters

    EPA Science Inventory

    Climate change is accelerating the release of dissolved organic matter (DOM) to inland and coastal waters through increases in precipitation, thawing of permafrost, and changes in vegetation. Our modeling approach suggests that the selective absorption of ultraviolet radiation (U...

  3. Ultraviolet radiation effects on the infrared damage rate of a thermal control coating

    NASA Technical Reports Server (NTRS)

    Bass, J. A.

    1972-01-01

    The effects of ultraviolet radiation on the infrared reflectance of ZnO silicone white thermal coatings were investigated. Narrow band ultraviolet radiation for wavelengths in the 2200A to 3500A range by a monochromator and a high pressure, 150-W Eimac xenon lamp. The sample was irradiated while in a vacuum of at least 0.000001 torr, and infrared reflectance was measured in situ with a spectroreflectometer at 19,500A. Reflectance degradation was studied as a function of wavelength, time, intensity, and dose. Damage was wavelength dependent at constant exposure, but no maximum was evident above the shortest wavelength investigated here. The degradation rate at constant intensity was an exponential function of time and varies with intensity.

  4. Method for plasma formation for extreme ultraviolet lithography-theta pinch

    DOEpatents

    Hassanein, Ahmed [Naperville, IL; Konkashbaev, Isak [Bolingbrook, IL; Rice, Bryan [Hillsboro, OR

    2007-02-20

    A device and method for generating extremely short-wave ultraviolet electromagnetic wave, utilizing a theta pinch plasma generator to produce electromagnetic radiation in the range of 10 to 20 nm. The device comprises an axially aligned open-ended pinch chamber defining a plasma zone adapted to contain a plasma generating gas within the plasma zone; a means for generating a magnetic field radially outward of the open-ended pinch chamber to produce a discharge plasma from the plasma generating gas, thereby producing a electromagnetic wave in the extreme ultraviolet range; a collecting means in optical communication with the pinch chamber to collect the electromagnetic radiation; and focusing means in optical communication with the collecting means to concentrate the electromagnetic radiation.

  5. Voyager investigation of the cosmic diffuse background: Observations of rocket-studied locations with Voyager

    NASA Technical Reports Server (NTRS)

    Henry, Richard C.

    1994-01-01

    Attachments to this final report include 2 papers connected with the Voyager work: 'Voyager Observations of Dust Scattering Near the Coalsack Nebula' and 'Search for the Intergalactic Medium'. An appendix of 12 one-page write-ups prepared in connection with another program, UVISI, is also included. The one-page write-ups are: (1) Sky survey of UV point sources to 600 times fainter than previous (TD-1) survey; (2) Diffuse galactic light: starlight scattered from dust at high galactic latitude; (3) Optical properties of interstellar grains; (4) Fluorescence of molecular hydrogen in the interstellar medium; (5) Line emission from hot interstellar medium and/or hot halo of galaxy; (6) Integrated light of distant galaxies in the ultraviolet; (7) Intergalactic far-ultraviolet radiation field; (8) Radiation from recombining intergalactic medium; (9) Radiation from re-heating of intergalactic medium following recombination; (10) Radiation from radiative decay of dark matter candidates (neutrino, etc.); (11) Reflectivity of the asteroids in the Ultraviolet; and (12) Zodiacal light.

  6. Selective effect of irradiation on responses to thymus-independent antigen.

    PubMed

    Lee, S K; Woodland, R T

    1985-02-01

    Low doses of ionizing radiation have a selective immunosuppressive effect on in vivo B cell responses to thymus-independent (TI) antigens. The B cell response, assayed as direct anti-trinitrophenyl (TNP)-specific plaque-forming cells (PFC), induced by type 2, TI antigens (TNP-Ficoll or TNP-Dextran), was reduced, on the average, by 10-fold in animals exposed to 200 rad of ionizing radiation 24 hr before antigen challenge. In contrast, PFC responses to type 1, TI antigens (TNP-lipopolysaccharide or TNP-Brucella abortus) are unaffected in mice exposed to the same dose of radiation. Adoptive transfers showed that this selective immunosuppression is a result of the specific inactivation of the B cell subpopulation responding to type 2, TI antigens. These experiments suggest that physiologic differences exist in the B cell subpopulations of normal mice which respond to type 1, or type 2, TI antigens.

  7. Key issues of ultraviolet radiation of OH at high altitudes

    NASA Astrophysics Data System (ADS)

    Zhang, Yuhuai; Wan, Tian; Jiang, Jianzheng; Fan, Jing

    2014-12-01

    Ultraviolet (UV) emissions radiated by hydroxyl (OH) is one of the fundamental elements in the prediction of radiation signature of high-altitude and high-speed vehicle. In this work, the OH A2Σ+→ X2Π ultraviolet emission band behind the bow shock is computed under the experimental condition of the second bow-shock ultraviolet flight (BSUV-2). Four related key issues are discussed, namely, the source of hydrogen element in the high-altitude atmosphere, the formation mechanism of OH species, efficient computational algorithm of trace species in rarefied flows, and accurate calculation of OH emission spectra. Firstly, by analyzing the typical atmospheric model, the vertical distributions of the number densities of different species containing hydrogen element are given. According to the different dominating species containing hydrogen element, the atmosphere is divided into three zones, and the formation mechanism of OH species is analyzed in the different zones. The direct simulation Monte Carlo (DSMC) method and the Navier-Stokes equations are employed to compute the number densities of the different OH electronically and vibrationally excited states. Different to the previous work, the trace species separation (TSS) algorithm is applied twice in order to accurately calculate the densities of OH species and its excited states. Using a non-equilibrium radiation model, the OH ultraviolet emission spectra and intensity at different altitudes are computed, and good agreement is obtained with the flight measured data.

  8. DELAY OF CLEAVAGE OF THE ARBACIA EGG BY ULTRAVIOLET RADIATION

    PubMed Central

    Blum, Harold F.; Price, Judith P.

    1950-01-01

    While our data do not permit us to state the exact locus or mode of action of ultraviolet radiation in the Arbacia egg, certain general conclusions may be reached. The amount of delay of cleavage of these eggs is determined by two principal factors: (1) The extent of an effect, resulting from photochemical action induced by ultraviolet radiation, which is reversible in a biological sense, the reversibility not being directly dependent upon the process of cell division. (2) The sensitivity of the cell division process to the effects of the ultraviolet-induced photochemical reaction. This factor varies with the stage of cell division, the cell being insensitive during a period corresponding to most of mitosis. It seems likely that these findings may apply to cell division in general, but, since the quantitative relationships observed must, in this case, reflect the integration of two semi-independent factors, the over-all picture may appear quite different for different kinds of cells. PMID:15410486

  9. Fundamental investigation of ultraviolet radiation effects in polymeric film-forming materials

    NASA Technical Reports Server (NTRS)

    Giori, C.; Yamauchi, T.; Llewellen, P.; Gilligan, J.

    1974-01-01

    A literature search from 1958 to present was conducted on the effect of ultraviolet radiation on polymeric materials, with particular emphasis on vacuum photolysis, mechanisms of degradation, and energy transfer phenomena. The literature from 1958 to 1968 was searched manually, while the literature from 1968 to present was searched by using a computerized keyword system. The primary objective was to provide the necessary background information for the design of new or modified materials with improved stability to the vacuum-radiation environment of space.

  10. Impact of soil moisture and winter wheat height from the Loess Plateau in Northwest China on surface spectral albedo

    NASA Astrophysics Data System (ADS)

    Li, Zhenchao; Yang, Jiaxi; Gao, Xiaoqing; Zheng, Zhiyuan; Yu, Ye; Hou, Xuhong; Wei, Zhigang

    2018-02-01

    The understanding of surface spectral radiation and reflected radiation characteristics of different surfaces in different climate zones aids in the interpretation of regional surface energy transfers and the development of land surface models. This study analysed surface spectral radiation variations and corresponding surface albedo characteristics at different wavelengths as well as the relationship between 5-cm soil moisture and surface albedo on typical sunny days during the winter wheat growth period. The analysis was conducted using observational Loess Plateau winter wheat data from 2015. The results show that the ratio of atmospheric downward radiation to global radiation on typical sunny days is highest for near-infrared wavelengths, followed by visible wavelengths and ultraviolet wavelengths, with values of 57.3, 38.7 and 4.0%, respectively. The ratio of reflected spectral radiation to global radiation varies based on land surface type. The visible radiation reflected by vegetated surfaces is far less than that reflected by bare ground, with surface albedos of 0.045 and 0.27, respectively. Thus, vegetated surfaces absorb more visible radiation than bare ground. The atmospheric downward spectral radiation to global radiation diurnal variation ratios vary for near-infrared wavelengths versus visible and ultraviolet wavelengths on typical sunny days. The near-infrared wavelengths ratio is higher in the morning and evening and lower at noon. The visible and ultraviolet wavelengths ratios are lower in the morning and evening and higher at noon. Visible and ultraviolet wavelength surface albedo is affected by 5-cm soil moisture, demonstrating a significant negative correlation. Excluding near-infrared wavelengths, correlations between surface albedo and 5-cm soil moisture pass the 99% confidence test at each wavelength. The correlation with 5-cm soil moisture is more significant at shorter wavelengths. However, this study obtained surface spectral radiation characteristics that were affected by land surface vegetation coverage as well as by soil physical properties.

  11. Minimum exposure limits and measured relationships between the vitamin D, erythema and international commission on non-ionizing radiation protection solar ultraviolet.

    PubMed

    Downs, Nathan; Parisi, Alfio; Butler, Harry; Turner, Joanna; Wainwright, Lisa

    2015-01-01

    The International Commission on Non-Ionizing Radiation Protection (ICNIRP) has established guidelines for exposure to ultraviolet radiation in outdoor occupational settings. Spectrally weighted ICNIRP ultraviolet exposures received by the skin or eye in an 8 h period are limited to 30 J m(-2). In this study, the time required to reach the ICNIRP exposure limit was measured daily in 10 min intervals upon a horizontal plane at a subtropical Australian latitude over a full year and compared with the effective Vitamin D dose received to one-quarter of the available skin surface area for all six Fitzpatrick skin types. The comparison of measured solar ultraviolet exposures for the full range of sky conditions in the 2009 measurement period, including a major September continental dust event, show a clear relationship between the weighted ICNIRP and the effective vitamin D dose. Our results show that the horizontal plane ICNIRP ultraviolet exposure may be used under these conditions to provide minimum guidelines for the healthy moderation of vitamin D, scalable to each of the six Fitzpatrick skin types. © 2014 The American Society of Photobiology.

  12. Evaluation of Low-Earth-Orbit Environmental Effects on International Space Station Thermal Control Materials

    NASA Technical Reports Server (NTRS)

    Dever, Joyce A.

    1998-01-01

    Many spacecraft thermal control coatings in low Earth orbit (LEO) can be affected by solar ultraviolet radiation and atomic oxygen. Ultraviolet radiation can darken some polymers and oxides commonly used in thermal control materials. Atomic oxygen can erode polymer materials, but it may reverse the ultraviolet-darkening effect on oxides. Maintaining the desired solar absorptance for thermal control coatings is important to assure the proper operating temperature of the spacecraft. Thermal control coatings to be used on the International Space Station (ISS) were evaluated for their performance after exposure in the NASA Lewis Research Center's Atomic Oxygen-Vacuum Ultraviolet Exposure (AO-VUV) facility. This facility simulated the LEO environments of solar vacuum ultraviolet (VUV) radiation (wavelength range, 115 to 200 nanometers (nm)) and VUV combined with atomic oxygen. Solar absorptance was measured in vacuo to eliminate the "bleaching" effects of ambient oxygen on VUV-induced degradation. The objective of these experiments was to determine solar absorptance increases of various thermal control materials due to exposure to simulated LEO conditions similar to those expected for ISS. Work was done in support of ISS efforts at the requests of Boeing Space and Defense Systems and Lockheed Martin Vought Systems.

  13. Accelerated Solar-UV Test Chamber

    NASA Technical Reports Server (NTRS)

    Gupta, A.; Laue, E. G.

    1984-01-01

    Medium-pressure mercury-vapor lamps provide high ratio of ultraviolet to total power. Chamber for evaluating solar-ultraviolet (UV) radiation damage permits accelerated testing without overheating test specimens.

  14. The relationship between ultraviolet radiation exposure and vitamin D status.

    PubMed

    Engelsen, Ola

    2010-05-01

    This paper reviews the main factors influencing the synthesis of vitamin D, with particular focus on ultraviolet radiation exposure. On the global level, the main source of vitamin D is the sun. The effect of solar radiation on vitamin D synthesis depends to some extent on the initial vitamin D levels. At moderate to high latitudes, diet becomes an increasingly important source of vitamin D due to decreased solar intensity and cold temperatures, which discourage skin exposure. During the mid-winter season, these factors result in decreased solar radiation exposure, hindering extensively the synthesis of vitamin D in these populations.

  15. Fine Forecasts: Encouraging the Media to Include Ultraviolet Radiation Information in Summertime Weather Forecasts

    ERIC Educational Resources Information Center

    Richards, R.; Reeder, A. I.; Bulliard, J.-L.

    2004-01-01

    Melanoma and skin cancer are largely attributable to over-exposure to solar ultraviolet radiation (UVR). Reports of UVR levels within media weather forecasts appear to be well received by the public and have good potential to communicate the need for appropriate sun protection to a broad audience. This study describes provision of UVR messages by…

  16. Ultraviolet-B radiation induced crosslinking improves physical properties of cold- and warm-water fish gelatin gels and films

    USDA-ARS?s Scientific Manuscript database

    Cold- and warm-water fish gelatin granules were exposed to ultraviolet-B radiation for doses up to 29.7 J/cm2. Solutions and films were prepared from the granules. Gel electrophoresis and refractive index were used to examine changes in molecular weight of the samples. Also, the gel strength and rhe...

  17. Inactivation of uropathogenic Escherichia coli in ground chicken meat using high pressure processing and gamma radiation, and in purge and chicken meat surfaces by ultraviolet light

    USDA-ARS?s Scientific Manuscript database

    Uropathogenic Escherichia coli (UPEC) are common contaminants in meat and poultry. Nonthermal food safety intervention technologies used to improve safety and shelf-life of both human and pet foods can include high pressure processing (HPP), ionizing (gamma) radiation (GR), and ultraviolet light (UV...

  18. Ultraviolet-B radiation in a row-crop canopy: an extended 1-D model

    Treesearch

    Wei Gao; Richard H. Grant; Gordon M. Heisler; James R. Slusser

    2003-01-01

    A decrease in stratospheric ozone may result in a serious threat to plants, since biologically active short-wavelength ultraviolet-B (UV-B 280-320 nm) radiation will increase even with a relatively small decrease in ozone. Numerous investigations have demonstrated that the effect of UV-B enhancements on plants includes reduction in grain yield, alteration in species...

  19. A geometric ultraviolet-B radiation transfer model applied to vegetation canopies

    Treesearch

    Wei Gao; Richard H. Grant; Gordon M. Heisler; James R. Slusser

    2002-01-01

    The decrease in stratospheric ozone (O3) has prompted continued efforts to assess the potential damage to plant and animal life due to enhanced levels of solar ultraviolet (UV)-B (280-320 nm) radiation. The objective of this study was to develop and evaluate an analytical model to simulate the UV-B irradiance loading on horizontal below- canopy...

  20. Ultraviolet radiation-blocking characteristics of contact lenses: relevance to eye protection for psoralen-sensitised patients.

    PubMed

    Anstey, A; Taylor, D; Chalmers, I; Ansari, E

    1999-10-01

    Nine brands of contact lens marketed as "UV protective" were tested for ultraviolet (UV) transmission in order to assess potential suitability for psoralen-sensitised patients. UV-transmission characteristics of hydrated lenses was tested with a Bentham monochromator spectro-radiometer system. All lenses showed minimal transmission loss in the visible band. The performance of the nine lenses was uniform for ultraviolet B radiation with negligible transmission, but showed variation in transmission for ultraviolet A radiation. None of the lenses complied with UV-transmission criteria used previously to assess UV-blocking spectacles. Only two lenses had UV-blocking characteristics which came close to the arbitrary criteria used. The performance of ordinary soft and hard lenses was very similar, with negligible blocking of UV radiation. None of the nine contact lenses marketed as "UV protective" excluded sufficient UVA to comply with criteria in current use to assess UV protection in spectacles for psoralen-sensitised patients. However, the improved UV-blocking characteristics of contact lenses identified in this paper compared to previous studies suggests that such a contact lens will soon become available. Meanwhile, contact lens-wearing systemically sensitised PUVA patients should continue to wear approved spectacles for eye protection whilst photosensitised with psoralen.

  1. The Space Weather and Ultraviolet Solar Variability (SWUSV) Microsatellite Mission

    PubMed Central

    Damé, Luc; Meftah, Mustapha; Hauchecorne, Alain; Keckhut, Philippe; Sarkissian, Alain; Marchand, Marion; Irbah, Abdenour; Quémerais, Éric; Bekki, Slimane; Foujols, Thomas; Kretzschmar, Matthieu; Cessateur, Gaël; Shapiro, Alexander; Schmutz, Werner; Kuzin, Sergey; Slemzin, Vladimir; Urnov, Alexander; Bogachev, Sergey; Merayo, José; Brauer, Peter; Tsinganos, Kanaris; Paschalis, Antonis; Mahrous, Ayman; Khaled, Safinaz; Ghitas, Ahmed; Marzouk, Besheir; Zaki, Amal; Hady, Ahmed A.; Kariyappa, Rangaiah

    2013-01-01

    We present the ambitions of the SWUSV (Space Weather and Ultraviolet Solar Variability) Microsatellite Mission that encompasses three major scientific objectives: (1) Space Weather including the prediction and detection of major eruptions and coronal mass ejections (Lyman-Alpha and Herzberg continuum imaging); (2) solar forcing on the climate through radiation and their interactions with the local stratosphere (UV spectral irradiance from 180 to 400 nm by bands of 20 nm, plus Lyman-Alpha and the CN bandhead); (3) simultaneous radiative budget of the Earth, UV to IR, with an accuracy better than 1% in differential. The paper briefly outlines the mission and describes the five proposed instruments of the model payload: SUAVE (Solar Ultraviolet Advanced Variability Experiment), an optimized telescope for FUV (Lyman-Alpha) and MUV (200–220 nm Herzberg continuum) imaging (sources of variability); UPR (Ultraviolet Passband Radiometers), with 64 UV filter radiometers; a vector magnetometer; thermal plasma measurements and Langmuir probes; and a total and spectral solar irradiance and Earth radiative budget ensemble (SERB, Solar irradiance & Earth Radiative Budget). SWUSV is proposed as a small mission to CNES and to ESA for a possible flight as early as 2017–2018. PMID:25685424

  2. The Space Weather and Ultraviolet Solar Variability (SWUSV) Microsatellite Mission.

    PubMed

    Damé, Luc

    2013-05-01

    We present the ambitions of the SWUSV (Space Weather and Ultraviolet Solar Variability) Microsatellite Mission that encompasses three major scientific objectives: (1) Space Weather including the prediction and detection of major eruptions and coronal mass ejections (Lyman-Alpha and Herzberg continuum imaging); (2) solar forcing on the climate through radiation and their interactions with the local stratosphere (UV spectral irradiance from 180 to 400 nm by bands of 20 nm, plus Lyman-Alpha and the CN bandhead); (3) simultaneous radiative budget of the Earth, UV to IR, with an accuracy better than 1% in differential. The paper briefly outlines the mission and describes the five proposed instruments of the model payload: SUAVE (Solar Ultraviolet Advanced Variability Experiment), an optimized telescope for FUV (Lyman-Alpha) and MUV (200-220 nm Herzberg continuum) imaging (sources of variability); UPR (Ultraviolet Passband Radiometers), with 64 UV filter radiometers; a vector magnetometer; thermal plasma measurements and Langmuir probes; and a total and spectral solar irradiance and Earth radiative budget ensemble (SERB, Solar irradiance & Earth Radiative Budget). SWUSV is proposed as a small mission to CNES and to ESA for a possible flight as early as 2017-2018.

  3. Reactor for simulation and acceleration of solar ultraviolet damage

    NASA Technical Reports Server (NTRS)

    Laue, E.; Gupta, A.

    1979-01-01

    An environmental test chamber providing acceleration of UV radiation and precise temperature control (+ or -)1 C was designed, constructed and tested. This chamber allows acceleration of solar ultraviolet up to 30 suns while maintaining temperature of the absorbing surface at 30 C - 60 C. This test chamber utilizes a filtered medium pressure mercury arc as the source of radiation, and a combination of selenium radiometer and silicon radiometer to monitor solar ultraviolet (295-340 nm) and total radiant power output, respectively. Details of design and construction and operational procedures are presented along with typical test data.

  4. Ultraviolet photometry from the Orbiting Astronomical Observatory. XXI - Absolute energy distribution of stars in the ultraviolet

    NASA Technical Reports Server (NTRS)

    Bless, R. C.; Code, A. D.; Fairchild, E. T.

    1976-01-01

    The absolute energy distribution in the ultraviolet is given for the stars alpha Vir, eta UMa, and alpha Leo. The calibration is based on absolute heterochromatic photometry between 2920 and 1370 A carried out with an Aerobee sounding rocket. The fundamental radiation standard is the synchrotron radiation from 240-MeV electrons in a certain synchrotron storage ring. On the basis of the sounding-rocket calibration, the preliminary OAO-2 spectrometer calibration has been revised; the fluxes for the three program stars are tabulated in energy per second per square centimeter per unit wavelength interval.

  5. Observed ozone response to variations in solar ultraviolet radiation

    NASA Technical Reports Server (NTRS)

    Gille, J. C.; Smythe, C. M.; Heath, D. F.

    1984-01-01

    During the winter of 1979, the solar ultraviolet irradiance varied with a period of 13.5 days and an amplitude of 1 percent. The zonal mean ozone values in the tropics varied with the solar irradiance, with an amplitude of 0.25 to 0.60 percent. This observation agrees with earlier calculations, although the response may be overestimated. These results imply changes in ozone at an altitude of 48 kilometers of up to 12 percent over an 11-year solar cycle. Interpretation of ozone changes in the upper stratosphere will require measurements of solar ultraviolet radiation at wavelengths near 200 nanometers.

  6. Natural Antioxidants: Multiple Mechanisms to Protect Skin From Solar Radiation

    PubMed Central

    Dunaway, Spencer; Odin, Rachel; Zhou, Linli; Ji, Liyuan; Zhang, Yuhang; Kadekaro, Ana L.

    2018-01-01

    Human skin exposed to solar ultraviolet radiation (UVR) results in a dramatic increase in the production of reactive oxygen species (ROS). The sudden increase in ROS shifts the natural balance toward a pro-oxidative state, resulting in oxidative stress. The detrimental effects of oxidative stress occur through multiple mechanisms that involve alterations to proteins and lipids, induction of inflammation, immunosuppression, DNA damage, and activation of signaling pathways that affect gene transcription, cell cycle, proliferation, and apoptosis. All of these alterations promote carcinogenesis and therefore, regulation of ROS levels is critical to the maintenance of normal skin homeostasis. Several botanical products have been found to exhibit potent antioxidant capacity and the ability to counteract UV-induced insults to the skin. These natural products exert their beneficial effects through multiple pathways, including some known to be negatively affected by solar UVR. Aging of the skin is also accelerated by UVR exposure, in particular UVA rays that penetrate deep into the epidermis and the dermis where it causes the degradation of collagen and elastin fibers via oxidative stress and activation of matrix metalloproteinases (MMPs). Because natural compounds are capable of attenuating some of the UV-induced aging effects in the skin, increased attention has been generated in the area of cosmetic sciences. The focus of this review is to cover the most prominent phytoproducts with potential to mitigate the deleterious effects of solar UVR and suitability for use in topical application. PMID:29740318

  7. Saving Your Students' Skin. Undergraduate Experiments that Probe UV Protection by Sunscreens and Sunglasses

    NASA Astrophysics Data System (ADS)

    Abney, James R.; Scalettar, Bethe A.

    1998-06-01

    Recent scientific evidence suggests that chlorofluorocarbons have substantially depleted the ozone layer, the earth's primary filter for ultraviolet radiation. At the same time, medical evidence has accumulated which suggests that exposure to ultraviolet radiation is a major cause of prevalent human health disorders, including skin cancer and cataracts. For these reasons, consumer purchases of sunscreens and sunglasses, which provide protection from ultraviolet radiation, have soared, and manufacturer interest in improving these products has intensified. This article describes absorption spectroscopy experiments that illustrate the mechanism of action of sunscreens and sunglasses and that highlight the differences between different products. The experiments are well suited to incorporation into an undergraduate science laboratory and will expose students to absorption phenomena in a familiar context with substantial environmental and medical relevance.

  8. The indirect antioxidant sulforaphane protects against thiopurine-mediated photooxidative stress

    PubMed Central

    Benedict, Andrea L.; Knatko, Elena V.; Dinkova-Kostova, Albena T.

    2012-01-01

    Long-term treatment with thiopurines, such as the widely used anticancer, immunosuppressive and anti-inflammatory agent azathioprine, combined with exposure to ultraviolet (UV) radiation is associated with increased oxidative stress, hyperphotosensitivity and high risk for development of aggressive squamous cell carcinomas of the skin. Sulforaphane, an isothiocyanate derived from broccoli, is a potent inducer of endogenous cellular defenses regulated by transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2), including cytoprotective enzymes and glutathione, which in turn act as efficient indirect and direct antioxidants that have long-lasting effects. Treatment with 6-thioguanine, a surrogate for azathioprine, leads to profound sensitization to oxidative stress and glutathione depletion upon exposure to UVA radiation, the damaging effects of which are primarily mediated by generation of reactive oxygen species. The degree of sensitization is greater for irradiation exposures spanning the absorption spectrum of 6-thioguanine, and is dependent on the length of treatment and the level of guanine substitution with 6-thioguanine, suggesting that the 6-thioguanine that is incorporated in genomic DNA is largely responsible for this sensitization. Sulforaphane provides protection against UVA, but not UVB, radiation without affecting the levels of 6-thioguanine incorporation into DNA. The protective effect is lost under conditions of Nrf2 deficiency, implying that it is due to induction of Nrf2-dependent cytoprotective proteins, and that this strategy could provide protection against any potentially photosensitizing drugs that generate electrophilic or reactive oxygen species. Thus, our findings support the development of Nrf2 activators as protectors against drug-mediated photooxidative stress and encourage future clinical trials in populations at high risk for cutaneous photodamage and photocarcinogenesis. PMID:22983983

  9. Detection of ultraviolet radiation using tissue equivalent radiochromic gel materials

    NASA Astrophysics Data System (ADS)

    Bero, M. A.; Abukassem, I.

    2009-05-01

    Ferrous Xylenol-orange Gelatin gel (FXG) is known to be sensitive to ionising radiation such as γ and X-rays. The effect of ionising radiation is to produce an increase in the absorption over a wide region of the visible spectrum, which is proportional to the absorbed dose. This study demonstrates that FXG gel is sensitive to ultraviolet radiation and therefore it could functions as UV detector. Short exposure to UV radiation produces linear increase in absorption measured at 550nm, however high doses of UV cause the ion indicator colour to fad away in a manner proportional to the incident UV energy. Light absorbance increase at the rate of 1.1% per minute of irradiation was monitored. The exposure level at which the detector has linear response is comparable to the natural summer UV radiation. Evaluating the UV ability to pass through tissue equivalent gel materials shows that most of the UV gets absorbed in the first 5mm of the gel materials, which demonstrate the damaging effects of this radiation type on human skin and eyes. It was concluded that FXG gel dosimeter has the potential to offer a simple, passive ultraviolet radiation detector with sensitivity suitable to measure and visualises the natural sunlight UV exposure directly by watching the materials colour changes.

  10. Ultraviolet radiation properties as applied to photoclimatherapy at the Dead Sea.

    PubMed

    Kudish, A I; Abels, D; Harari, M

    2003-05-01

    The Dead Sea basin, the lowest terrestrial point on earth, is recognized as a natural treatment center for patients with various cutaneous and rheumatic diseases. Psoriasis is the major skin disease treated at the Dead Sea with excellent improvement to complete clearance exceeding 85% after 4 weeks of treatment. These results were postulated to be associated with a unique spectrum of ultraviolet radiation present in the Dead Sea area. The UVB and UVA radiation at two sites is measured continuously by identical sets of broad-band Solar Light Co. Inc. meters (Philadelphia, PA). The spectral selectivity within the UVB and UVA spectrum was determined using a narrow-band spectroradiometer, UV-Optronics 742 (Orlando, FL). The optimum exposure time intervals for photoclimatherapy, defined as the minimum ratio of erythema to therapeutic radiation intensities, were also determined using a Solar Light Co. Inc. Microtops II, Ozone Monitor-Sunphotometer. The ultraviolet radiation at the Dead Sea is attenuated relative to Beer Sheva as a result of the increased optical path length and consequent enhanced scattering. The UVB radiation is attenuated to a greater extent than UVA and the shorter erythema UVB spectral range decreased significantly compared with the longer therapeutic UVB wavelengths. It was demonstrated that the relative attenuation within the UVB spectral range is greatest for the shorter erythema rays and less for the longer therapeutic UVB wavelengths, thus producing a greater proportion of the longer therapeutic UVB wavelengths in the ultraviolet spectrum. These measurements can be utilized to minimize the exposure to solar radiation by correlating the cumulative UVB radiation dose to treatment efficacy and by formulating a patient sun exposure treatment protocol for Dead Sea photoclimatherapy.

  11. 21 CFR 101.78 - Health claims: fruits and vegetables and cancer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... smoking, alcohol consumption, overweight and obesity, ultraviolet or ionizing radiation, exposure to... specific type of cancer, cigarette smoking, alcohol consumption, overweight and obesity, ultraviolet or...

  12. 21 CFR 101.78 - Health claims: fruits and vegetables and cancer.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... smoking, alcohol consumption, overweight and obesity, ultraviolet or ionizing radiation, exposure to... specific type of cancer, cigarette smoking, alcohol consumption, overweight and obesity, ultraviolet or...

  13. 21 CFR 101.78 - Health claims: fruits and vegetables and cancer.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... smoking, alcohol consumption, overweight and obesity, ultraviolet or ionizing radiation, exposure to... specific type of cancer, cigarette smoking, alcohol consumption, overweight and obesity, ultraviolet or...

  14. 21 CFR 101.78 - Health claims: fruits and vegetables and cancer.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... smoking, alcohol consumption, overweight and obesity, ultraviolet or ionizing radiation, exposure to... specific type of cancer, cigarette smoking, alcohol consumption, overweight and obesity, ultraviolet or...

  15. 21 CFR 101.78 - Health claims: fruits and vegetables and cancer.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... smoking, alcohol consumption, overweight and obesity, ultraviolet or ionizing radiation, exposure to... specific type of cancer, cigarette smoking, alcohol consumption, overweight and obesity, ultraviolet or...

  16. Dermatology Procedures

    MedlinePlus

    ... of psoralen (P) and long-wave ultraviolet radiation (UVA) that is used to treat several severe skin ... to ultraviolet light. This allows the deeply penetrating UVA band of light to work on the skin. ...

  17. From Radio to X-rays--Some 'Real' Electrical Applications.

    ERIC Educational Resources Information Center

    Freeman, J. C.

    1986-01-01

    Describes practical applications related to X-rays, ultra-violet radiation, light radiation, short-wave infra-red radiation, medium-wave infra-red radiation, long-wave infra-red radiation, microwave radiation, and radio frequency radiation. Suggests that these applications be used during instruction on electricity. (JN)

  18. Analysis of the UV-B Regime and Potential Effects on Alfalfa

    NASA Technical Reports Server (NTRS)

    Seitz, Jeffery C.

    1998-01-01

    Life at the surface of the Earth, over the last 400 m.y., evolved under conditions of decreased short-wave radiation (i.e., ultraviolet) relative to solar output due to absorption and scattering by constituents (e.g., ozone, water vapor, aerosols) in the upper atmosphere. However, a significant amount of ultraviolet radiation in the range from 280-320 nm, known as ultraviolet-B radiation, reaches the Earth's surface and has sufficient energy to be damaging to biologic tissue. Natural fluctuations in atmospheric constituents (seasonal variation, volcanic eruptions, etc.), changes in the orbital attitude of the Earth (precession, axial tilt, orbital eccentricity), and long-term solar variability contribute to changes in the total amount of ultraviolet radiation reaching the surface of the Earth, and thus, the biosphere. More recently, the atmospheric release of commercial propellants and refrigerants, known as chlorofluorocarbons (CFCs), has contributed to a significant depletion in naturally occurring ozone in the stratosphere. Thus, decreased stratospheric ozone has resulted in an increased UV-B flux at the Earth's surface which may have profound effects on terrestrial and marine organisms. In this study, we are investigating the effects of differing solar UV-B fluxes on alfalfa (Medicago sativa L.), an important agricultural crop. A long-term goal of this research is to develop spectral signatures to detect plant response to increased UV-B radiation from remote sensor platforms.

  19. Evaluation of an enclosed ultraviolet-C radiation device for decontamination of mobile handheld devices.

    PubMed

    Mathew, J Itty; Cadnum, Jennifer L; Sankar, Thriveen; Jencson, Annette L; Kundrapu, Sirisha; Donskey, Curtis J

    2016-06-01

    Mobile handheld devices used in health care settings may become contaminated with health care-associated pathogens. We demonstrated that an enclosed ultraviolet-C radiation device was effective in rapidly reducing methicillin-resistant Staphylococcus aureus, and with longer exposure times, Clostridium difficile spores, on glass slides and reducing contamination on in-use mobile handheld devices. Published by Elsevier Inc.

  20. Is the Global Solar UV Index an Effective Instrument for Promoting Sun Protection? A Systematic Review

    ERIC Educational Resources Information Center

    Italia, Nadia; Rehfuess, Eva A.

    2012-01-01

    Exposure to ultraviolet radiation is an important risk factor for skin cancer. The Global Solar Ultraviolet Index (UVI) was developed as a tool to visualize the amount of harmful radiation and to encourage people to use sun protection. We conducted a systematic review of the effectiveness of the UVI. We employed a comprehensive search strategy to…

  1. Broad-spectrum sunscreens offer protection against urocanic acid photoisomerization by artificial ultraviolet radiation in human skin.

    PubMed

    van der Molen, R G; Out-Luiting, C; Driller, H; Claas, F H; Koerten, H K; Mommaas, A M

    2000-09-01

    Cis-urocanic acid (UCA) has been indicated as an important mediator of ultraviolet (UV)-induced immunosuppression. In this study we describe a rapid, noninvasive method for the determination of the protective capacity of various sunscreens against the UV-induced isomerization of trans-UCA into its cis form. For this purpose we applied sunscreens prior to in vivo exposure of human volunteers with single or repeated broadband UVB irradiations of 100 mJ per cm2. We found significant but different levels of protection against UCA photoisomerization by all sunscreens that correlated with the sun protection factor. A comparison of various sunscreens with a sun protection factor of 10, showed that the best protection was offered by the sunscreens (containing organic UV filters or TiO2) with broad absorption spectra. The ability to inhibit cis-UCA formation was not influenced by the penetration characteristics of sunscreens, as determined by application of the sunscreen on quartz glass that was placed on the skin, preventing penetration of sunscreen in the skin. In addition ex vivo UV exposure of human skin was employed to permit other tests of immunomodulation, in this case the mixed epidermal cell lymphocyte reaction. The advantage of this ex vivo method is that there is no need to take biopsies from volunteers. Ex vivo irradiation of human skin with a single dose of 200 mJ per cm2 resulted in similar protection by the sunscreens against cis-UCA formation as in the in vivo system. Furthermore, the mixed epidermal cell lymphocyte reaction data correlated with the cis-UCA findings. We conclude that UCA isomerization is an excellent method to determine sunscreen efficacy and that broad-spectrum sunscreens offer good immunoprotection.

  2. Key issues of ultraviolet radiation of OH at high altitudes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Yuhuai; Wan, Tian; Jiang, Jianzheng

    2014-12-09

    Ultraviolet (UV) emissions radiated by hydroxyl (OH) is one of the fundamental elements in the prediction of radiation signature of high-altitude and high-speed vehicle. In this work, the OH A{sup 2}Σ{sup +}→X{sup 2}Π ultraviolet emission band behind the bow shock is computed under the experimental condition of the second bow-shock ultraviolet flight (BSUV-2). Four related key issues are discussed, namely, the source of hydrogen element in the high-altitude atmosphere, the formation mechanism of OH species, efficient computational algorithm of trace species in rarefied flows, and accurate calculation of OH emission spectra. Firstly, by analyzing the typical atmospheric model, the verticalmore » distributions of the number densities of different species containing hydrogen element are given. According to the different dominating species containing hydrogen element, the atmosphere is divided into three zones, and the formation mechanism of OH species is analyzed in the different zones. The direct simulation Monte Carlo (DSMC) method and the Navier-Stokes equations are employed to compute the number densities of the different OH electronically and vibrationally excited states. Different to the previous work, the trace species separation (TSS) algorithm is applied twice in order to accurately calculate the densities of OH species and its excited states. Using a non-equilibrium radiation model, the OH ultraviolet emission spectra and intensity at different altitudes are computed, and good agreement is obtained with the flight measured data.« less

  3. ULTRAVIOLET SPECTROSCOPY OF BL Hyi AND EF Eri IN HIGH AND INTERMEDIATE STATES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sanad, M. R.; Abdel-Sabour, M. A.

    2016-08-01

    We present the first phase-resolved ultraviolet spectroscopy of two polar systems, BL Hyi and EF Eri, in high and intermediate states from the International Ultraviolet Explorer ( IUE ) during the periods between 1982–1995 and 1979–1991, respectively. The flux curves for the C iv and He ii emission lines for both systems showing variations in their fluxes at different orbital phases are presented. The emission lines are produced in the accretion stream. The reddening for the two polars is found to be 0.00. Our results show that there are variations of the line fluxes with time, similar to the lightmore » curves found for both BL Hyi and EF Eri in the optical, infrared, ultraviolet, and X-ray bands. IUE observations support a radiative shock model of BL Hyi with the heating of matter by radiation from the accretion shock and cooling by the electrons scattering off ultraviolet photons from the surface of the white dwarf. EF Eri observations support a two-temperature white dwarf model producing sufficient ultraviolet flux for orbital modulations.« less

  4. Change in the thermionic work function of semiconductor powders exposed to electromagnetic radiation

    NASA Technical Reports Server (NTRS)

    Bourasseau, S.; Martin, J. R.; Juillet, F.; Teichner, S. J.

    1977-01-01

    The variations of the thermoelectronic work function of titanium dioxide, submitted to an ultraviolet or visible and infrared radiation, in the presence of oxygen, are studied by the vibrating condenser method. It is shown that during the ultraviolet irradiation, a desorption of a first species of oxygen simultaneously occurs with the adsorption of a second species of oxygen and that this phenomenon is found for any structure of TiO2 (anatase or rutile) any texture, oxygen pressure, radiation intensity, and nature of introduced dopes.

  5. Ultraviolet radiation emitted by lamps, TVs, tablets and computers: are there risks for the population?

    PubMed

    Duarte, Ida Alzira Gomes; Hafner, Mariana de Figueiredo Silva; Malvestiti, Andrey Augusto

    2015-01-01

    The frequent human exposure to various types of indoor lamps, as well as other light sources (television monitors, tablets and computers), raises a question: are there risks for the population? In the present study the emission of UVA and UVB radiation by lamps and screens of electronic devices were measured in order to determine the safe distance between the emitting source and the individual. We concluded that the lamps and electronic devices do not emit ultraviolet radiation; so they pose no health risk for the population.

  6. Medical Devices; General Hospital and Personal Use Devices; Classification of the Ultraviolet Radiation Chamber Disinfection Device. Final order.

    PubMed

    2015-11-20

    The Food and Drug Administration (FDA or the Agency) is classifying the ultraviolet (UV) radiation chamber disinfection device into class II (special controls). The special controls that will apply to the device are identified in this order and will be part of the codified language for the UV radiation chamber disinfection device classification. The Agency is classifying the device into class II (special controls) in order to provide a reasonable assurance of safety and effectiveness of the device.

  7. Androgenic alopecia may have evolved to protect men from prostate cancer by increasing skin exposure to ultraviolet radiation.

    PubMed

    Kabai, Peter

    2008-01-01

    Androgenic alopecia affects populations adapted to colder climate, and individuals at an age and hormonal status susceptible to prostate cancer. Male pattern baldness enhances absorption of UV radiation on the top of the head, an area directly exposed to sunlight during everyday activities. Ultraviolet radiation is reported to reduce the risk of advanced prostate cancer. Here I propose that progression of androgenic alopecia rather than being a risk factor is a finely tuned mechanism evolved to protect against prostate cancer.

  8. Ultraviolet radiation emitted by lamps, TVs, tablets and computers: are there risks for the population?

    PubMed Central

    Duarte, Ida Alzira Gomes; Hafner, Mariana de Figueiredo Silva; Malvestiti, Andrey Augusto

    2015-01-01

    The frequent human exposure to various types of indoor lamps, as well as other light sources (television monitors, tablets and computers), raises a question: are there risks for the population? In the present study the emission of UVA and UVB radiation by lamps and screens of electronic devices were measured in order to determine the safe distance between the emitting source and the individual. We concluded that the lamps and electronic devices do not emit ultraviolet radiation; so they pose no health risk for the population. PMID:26375236

  9. An ESR study of the UV degradation of FEP

    NASA Technical Reports Server (NTRS)

    George, G. A.; Hill, D. J. T.; Odonnell, J. H.; Pomery, P. J.; Rasoul, F.

    1992-01-01

    Spacecraft in low earth orbit are subjected to significant levels of high energy radiation, including ultraviolet (UV) and visible ultraviolet (VUV) wavelengths. The effects of UV radiation are enhanced over those at the surface of the earth, where the only incident wavelengths are greater than 290 nm. In low earth orbit the incident UV wavelengths extend below 290 nm into the VUV region, where the Lyman alpha-emissions of atomic hydrogen occur at 121 nm. In addition to electromagnetic radiation, in low earth orbit polymer materials may also be subjected to atomic oxygen particle radiation, which will result in direct oxidation of the polymer.

  10. A study on resistance to ultraviolet radiation of POSS-TiO2/epoxy nanocomposites

    NASA Astrophysics Data System (ADS)

    Peng, Dequn; Qin, Wei; Wu, Xiaohong

    2015-06-01

    Ultraviolet (UV) radiation is a severe space environmental factor, which is harmful to the durability of the polymeric materials of the spacecraft. For this reason, a novel POSS-TiO2/EP nanocomposite was synthesized by incorporating the POSS-TiO2 organic-inorganic hybrid into the epoxy (EP) resin. The effects of UV radiation on EP resin and on POSS-TiO2/EP nanocomposites were investigated in a ground-based simulator that simulates space radiation conditions. Compared with EP resin, the value of bend strength for 5.0 wt% POSS-TiO2/EP varied in a small range before and after UV radiation. Meanwhile, a typical tough feature was observed from the SEM photo for POSS-TiO2/EP nanocomposite after UV exposure. This result indicated that the POSS-TiO2/EP exhibited the excellent properties of anti-space ultraviolet radiation. The thermo gravimetric (TG) results showed that the addition of POSS-TiO2 improved the thermal-stability of EP resin matrix. The synthesized nanocomposites in this work could be used in the satellites to enhance their adaptability to the space environment and extend their service life.

  11. Micro-Raman spectroscopy study of the effect of Mid-Ultraviolet radiation on erythrocyte membrane.

    PubMed

    Li, N; Li, S X; Guo, Z Y; Zhuang, Z F; Li, R; Xiong, K; Chen, S J; Liu, S H

    2012-07-02

    Mid-Ultraviolet (UVB) has a significant influence on human health. In this study, human erythrocytes were exposed to UVB to investigate the effects of UVB radiation on erythrocytes membrane. And Micro-Raman spectroscopy was employed to detect the damage. Principal component analysis (PCA) was used to classify the control erythrocytes and the irradiated erythrocytes. Results showed that the erythrocytes membrane was damaged by Mid-Ultraviolet (UVB) radiation. The intensity of the Raman peaks at 1126 cm(-1) and 1082 cm(-1) were used to calculate the Longitudinal Order-Parameters in Chains (S(trans)) which can present the liquidity and ionic permeability of erythrocyte membrane. After UVB radiation for 30 min, both the liquidity and ionic permeability decreased. At the same time, the intensity of the peaks at 1302 cm(-1) (α-helix), 1254 cm(-1) (random coil), 1452 cm(-1) and 1430 cm(-1) (CH(2)/CH(3) stretch) have also changed which indicated the membrane protein also been damaged by UVB. In the whole process of radiation, the more UVB radiation dose the more damage on the erythrocyte membrane. Copyright © 2012 Elsevier B.V. All rights reserved.

  12. Establishing a ultraviolet radiation observational network and enhancing the study on ultraviolet radiation

    NASA Astrophysics Data System (ADS)

    Bai, Jianhui; Wang, Gengchen

    2003-09-01

    On the basis of analyzing observational data on solar radiation, meteorological parameters, and total ozone amount for the period of January 1990 to December 1991 in the Beijing area, an empirical calculation method for ultraviolet radiation (UV) in clear sky is obtained. The results show that the calculated values agree well with the observed, with maximum relative bias of 6.2% and mean relative bias for 24 months of 1.9%. Good results are also obtained when this method is applied in Guangzhou and Mohe districts. The long-term variation of UV radiation in clear sky over the Beijing area from 1979 to 1998 is calculated, and the UV variation trends and causes are discussed: direct and indirect UV energy absorption by increasing pollutants in the troposphere may have caused the UV decrease in clear sky in the last 20 years. With the enhancement of people’s quality of life and awareness of health, it will be valuable and practical to provid UV forecasts for typical cities and rural areas. So, we should develop and enhance UV study in systematic monitoring, forecasting, and developing a good and feasible method for UV radiation reporting in China, especially for big cities.

  13. Ultraviolet Radiation Induction of Mutation in Penicillium Claviforme.

    ERIC Educational Resources Information Center

    New, June; Jolley, Ray

    1986-01-01

    Cites reasons why Penicillium claviforme is an exceptionally good species for ultraviolet induced mutation experiments. Provides a set of laboratory instructions for teachers and students. Includes a discussion section. (ML)

  14. Cavity-enhanced frequency doubling from 795nm to 397.5nm ultra-violet coherent radiation with PPKTP crystals in the low pump power regime.

    PubMed

    Wen, Xin; Han, Yashuai; Bai, Jiandong; He, Jun; Wang, Yanhua; Yang, Baodong; Wang, Junmin

    2014-12-29

    We demonstrate a simple, compact and cost-efficient diode laser pumped frequency doubling system at 795 nm in the low power regime. In two configurations, a bow-tie four-mirror ring enhancement cavity with a PPKTP crystal inside and a semi-monolithic PPKTP enhancement cavity, we obtain 397.5nm ultra-violet coherent radiation of 35mW and 47mW respectively with a mode-matched fundamental power of about 110mW, corresponding to a conversion efficiency of 32% and 41%. The low loss semi-monolithic cavity leads to the better results. The constructed ultra-violet coherent radiation has good power stability and beam quality, and the system has huge potential in quantum optics and cold atom physics.

  15. Photoenhanced toxicity of a carbamate insecticide to early life stage anuran amphibians

    USGS Publications Warehouse

    Zaga, A.; Little, E.E.; Rabeni, C.F.; Ellersieck, Mark R.

    1998-01-01

    Aican clawed frog (Xenopus laevis) and gray tree frog (Hyla versicolor) embryos and tadpoles were exposed to sublethal levels of carbaryl, a broad-spectrum insecticide, and ultraviolet radiation to determine interactive and sublethal effects. Ultraviolet intensity (UV-B [285–320 nm] plus UV-A [321–400 nm]) was controlled with various types of plastic filters and quantified with a scanning spectroradiometer. Significant differences in swimming activity and mortality of both species were evident during the 96-h experiments. Ultraviolet-B radiation alone and carbaryl in the presence of UV-B significantly decreased swimming activity of both species. As little as 1.5% intensity of ambient solar UV-B radiation photoactivated carbaryl. Toxicity of 7.5 mg/L carbaryl increased by 10-fold in the presence of UV-B in all species and life stages tested. Our results indicate that photoenhancement by solar UV-B radiation should be considered when evaluating the toxicity of contaminants to amphibians and other organisms.

  16. Development of space stable thermal control coatings for use on large space vehicles. [effects of ultraviolet radiation

    NASA Technical Reports Server (NTRS)

    Gilligan, J. E.; Harada, Y.

    1974-01-01

    The development of a large scale manufacturing method for the production of a stable zinc orthotitanate pigment is discussed. Major emphasis was placed on the evaluation of ultraviolet radiation stability tests of pigments derived from coprecipitated and individually precipitated oxalates. Emphasis was also placed on an investigation of the conditions (time and temperature) leading to high reflectance and high optical stability. Paints were formulated in OI-650 and in OI-650G vehicles from pigments which were prepared at various temperatures. Analyses of ultraviolet irradiation test data were conducted regarding optimum pigment preparation parameters and treatment conditions.

  17. Investigation of space radiation effects in polymeric film-forming materials

    NASA Technical Reports Server (NTRS)

    Giori, C.; Yamauchi, T.; Jarke, F.

    1975-01-01

    The literature search in the field of ultraviolet radiation effects that was conducted during the previous program, Contract No. NAS1-12549, has been expanded to include the effects of charged particle radiation and high energy electromagnetic radiation. The literature from 1958 to 1969 was searched manually, while the literature from 1969 to present was searched by using a computerized keyword system. The information generated from this search was utilized for the design of an experimental program aimed at the development of materials with improved resistance to the vacuum-radiation environment of space. Preliminary irradiation experiments were performed which indicate that the approaches and criteria employed are very promising and may provide a solution to the challenging problem of polymer stability to combined ultraviolet/high energy radiation.

  18. Impact of plasma jet vacuum ultraviolet radiation on reactive oxygen species generation in bio-relevant liquids

    NASA Astrophysics Data System (ADS)

    Jablonowski, H.; Bussiahn, R.; Hammer, M. U.; Weltmann, K.-D.; von Woedtke, Th.; Reuter, S.

    2015-12-01

    Plasma medicine utilizes the combined interaction of plasma produced reactive components. These are reactive atoms, molecules, ions, metastable species, and radiation. Here, ultraviolet (UV, 100-400 nm) and, in particular, vacuum ultraviolet (VUV, 10-200 nm) radiation generated by an atmospheric pressure argon plasma jet were investigated regarding plasma emission, absorption in a humidified atmosphere and in solutions relevant for plasma medicine. The energy absorption was obtained for simple solutions like distilled water (dH2O) or ultrapure water and sodium chloride (NaCl) solution as well as for more complex ones, for example, Rosewell Park Memorial Institute (RPMI 1640) cell culture media. As moderate stable reactive oxygen species, hydrogen peroxide (H2O2) was studied. Highly reactive oxygen radicals, namely, superoxide anion (O2•-) and hydroxyl radicals (•OH), were investigated by the use of electron paramagnetic resonance spectroscopy. All species amounts were detected for three different treatment cases: Plasma jet generated VUV and UV radiation, plasma jet generated UV radiation without VUV part, and complete plasma jet including all reactive components additionally to VUV and UV radiation. It was found that a considerable amount of radicals are generated by the plasma generated photoemission. From the experiments, estimation on the low hazard potential of plasma generated VUV radiation is discussed.

  19. Method for detecting radiation dose utilizing thermoluminescent material

    DOEpatents

    Miller, Steven D.; McDonald, Joseph C.; Eichner, Fred N.; Tomeraasen, Paul L.

    1991-01-01

    The amount of ionizing radiation to which a thermoluminescent material has been exposed is determined by first cooling the thermoluminescent material to a cryogenic temperature. The thermoluminescent material is then optically stimulated by exposure to ultraviolet light. Visible light emitted by the thermoluminescent material as it is allowed to warm up to room temperature is detected and counted. The thermoluminescent material may be annealed by exposure to ultraviolet light.

  20. Next-Generation Fire Extinguishing Agent. Phase 4. Foundation for New Training Agent Development

    DTIC Science & Technology

    1989-12-01

    Administration PCE perchloroethylene PEL Permissible Exposure Limit QSAR Quantitative Structure Activity Relationship SBUV Solar Backscatter Ultraviolet xi...can pass through the troposphere without destruction to enter the stratosphere. In the stratosphere, they photolyze in the intense solar radiation to...radiation, UV-B, striking the earth. Preliminary data from a Solar Backscatter Ultraviolet (SBUV) instrument aboard NASA’s Nimbus 7 satellite show a

  1. Epidemiologic evidence for different roles of ultraviolet A and B radiation in melanoma mortality rates.

    PubMed

    Garland, Cedric F; Garland, Frank C; Gorham, Edward D

    2003-07-01

    The action spectrum of ultraviolet radiation mainly responsible for melanoma induction is unknown, but evidence suggests it could be ultraviolet A (UVA), which has a different geographic distribution than ultraviolet B (UVB). This study assessed whether melanoma mortality rates are more closely related to the global distribution of UVA or UVB. UVA and UVB radiation and age-adjusted melanoma mortality rates were obtained for all 45 countries reporting cancer data to the World Health Organization. Stratospheric ozone data were obtained from NASA satellites. Average population skin pigmentation was obtained from skin reflectometry measurements. Paradoxically, melanoma mortality rates decreased with increasing UVB in men (r = -0.48, p < 0.001), and women (r = -0.57, p < 0.001), and with increasing UVA in both sexes. By contrast, rates were positively associated with increasing UVA/UVB ratio in men (r = + 0.49, p < 0.001) and women (r = + 0.55, p < 0.001). After multiple adjustment that included controlling for skin pigmentation, only UVA was associated with melanoma mortality rates in men (p < 0.02) with a suggestive but non-significant trend present in women (p = 0.12). UVA radiation was associated with melanoma mortality rates after controlling for UVB and average pigmentation. The results require confirmation in observational studies.

  2. Autonomous portable solar ultraviolet spectroradiometer (APSUS) - a new CCD spectrometer system for localized, real-time solar ultraviolet (280-400 nm) radiation measurement.

    PubMed

    Hooke, Rebecca; Pearson, Andy; O'Hagan, John

    2014-01-01

    Terrestrial solar ultraviolet (UV) radiation has significant implications for human health and increasing levels are a key concern regarding the impact of climate change. Monitoring solar UV radiation at the earth's surface is therefore of increasing importance. A new prototype portable CCD (charge-coupled device) spectrometer-based system has been developed that monitors UV radiation (280-400 nm) levels at the earth's surface. It has the ability to deliver this information to the public in real time. Since the instrument can operate autonomously, it is called the Autonomous Portable Solar Ultraviolet Spectroradiometer (APSUS). This instrument incorporates an Ocean Optics QE65000 spectrometer which is contained within a robust environmental housing. The APSUS system can gather reliable solar UV spectral data from approximately April to October inclusive (depending on ambient temperature) in the UK. In this study the new APSUS unit and APSUS system are presented. Example solar UV spectra and diurnal UV Index values as measured by the APSUS system in London and Weymouth in the UK in summer 2012 are shown. © 2014 Crown copyright. Photochemistry and Photobiology © 2014 The American Society of Photobiology. This article is published with the permission of the Controller of HMSO and the Queen's Printer for Scotland and Public Health England.

  3. Aqueous humour and ultraviolet radiation.

    PubMed

    Ringvold, A

    1980-01-01

    Studies on the ultraviolet ray absorption in the aqueous humour of rabbit, cat, monkey, guinea pig, and rat showed marked species differences. In the rabbit aqueous the ascorbic acid, the proteins, and some amino acids (tyrosine, phenylalanine, cystine, and tryptophane) are together responsible for the total absorption, and a very great part of it refers to the ascorbic acid content. Accordingly, species with significant amounts of ascorbic acid in the aqueous (monkey, rabbit, guinea pig) have a greater absorption capacity towards ultraviolet radiation than species (cat, rat) lacking this substance. This effect of the ascorbic acid may contribute in protecting the lens against the most biotoxic ultraviolet rays. It seems that the ascorbic acid concentration is highest in the aqueous of typical day animals and lowest in species being active in the dark, indicating a correlation between the aqueous' ascorbic acid level and the quantity of incident light on the eye. The possible significance of changed aqueous ultraviolet ray absorption in the pathogenesis of human cataract development is discussed.

  4. Autonomous celestial navigation based on Earth ultraviolet radiance and fast gradient statistic feature extraction

    NASA Astrophysics Data System (ADS)

    Lu, Shan; Zhang, Hanmo

    2016-01-01

    To meet the requirement of autonomous orbit determination, this paper proposes a fast curve fitting method based on earth ultraviolet features to obtain accurate earth vector direction, in order to achieve the high precision autonomous navigation. Firstly, combining the stable characters of earth ultraviolet radiance and the use of transmission model software of atmospheric radiation, the paper simulates earth ultraviolet radiation model on different time and chooses the proper observation band. Then the fast improved edge extracting method combined Sobel operator and local binary pattern (LBP) is utilized, which can both eliminate noises efficiently and extract earth ultraviolet limb features accurately. And earth's centroid locations on simulated images are estimated via the least square fitting method using part of the limb edges. Taken advantage of the estimated earth vector direction and earth distance, Extended Kalman Filter (EKF) is applied to realize the autonomous navigation finally. Experiment results indicate the proposed method can achieve a sub-pixel earth centroid location estimation and extremely enhance autonomous celestial navigation precision.

  5. [Association between sunburn in children and ultraviolet radiation and ozone layer, during six summers (1996-2001) in Santiago, Chile (33,5 degrees S)].

    PubMed

    Aranibar, Ligia; Cabrera, Sergio; Honeyman, Juan

    2003-09-01

    During the recent 10 years the ozone layer has decreased while ultraviolet radiation has increased in Santiago, Chile. To determine whether the number of sunburns in children correlate with ultraviolet radiation in Santiago. During six Austral Summers (1996-2001) children below 15 years old, consulting for sunburn, were evaluated at the "Corporation for the Aid of Burned Children" (COANIQUEM) in Santiago (33.5 degrees S). The number of children with sunburns during each Summer was compared with the corresponding UV-B radiation and the ozone thickness, to establish a probable relation between a geophysical change and its consequences in skin health. The ozone layer values were obtained from the NASA WEB-page and the ultraviolet radiation was measured with a four-channel medium resolution radiometer. In each Summer there was a predominance of sunburns among boys and among ages between 6 and 10 years. During the 96-97 Austral Summer, the highest number of children with sunburns (63) was diagnosed. That Summer also had the highest mean UV-305 nm radiation with an important amount of days with ozone < or = 260 Dobson Units. Only during that Summer an inverse correlation between ozone and UV-305 nm radiation was detected. At the same time the maximal values of Erythemal Dose Rate (33 muWatt cm2), UV Index (13) and Erythemal Daily Dose (7.500 Joule m2) were observed. In Santiago, Summers with a higher number of days with low ozone protection seem to reappear every 3 years. Understanding the interaction of physical processes that control the ozone layer, may help to design better photo-protection programs for human health.

  6. Tolerance of an albino fish to ultraviolet-B radiation

    USGS Publications Warehouse

    Fabacher, David L.; Little, Edward E.; Ostrander, Gary K.

    1999-01-01

    We exposed albino and pigmented medakaOryzias latipes to simulated solar ultraviolet-B (UVB) radiation to determine if albino medaka were less tolerant of UVB radiation than medaka pigmented with melanin. There was no difference in the number of albino and pigmented medaka that died during the exposure period. Spectrophotometric analyses of the outer dorsal skin layers from albino and pigmented medaka indicated that, prior to exposure, both groups of fish had similar amounts of an apparent colorless non-melanin photoprotective substance that appears to protect other fish species from UVB radiation. Our results indicate that albino medaka were as tolerant of UVB radiation as pigmented medaka because they had similar amounts of this photoprotective substance in the outer layers of the skin.

  7. A Rare Presentation of Isolated CNS Posttransplantation Lymphoproliferative Disorder

    PubMed Central

    Smith, Casey; Streicher, Andrew; Magnuson, Allison; Newman, Susan; Bertoli, Robert

    2017-01-01

    Posttransplantation lymphoproliferative disorder (PTLD) is a recognized and extremely morbid complication of solid organ transplantation, but central nervous system involvement, particularly in isolation, is rare. There are no standardized treatment strategies for PTLD, though commonly used strategies include reduction of immunosuppression, chemotherapy, rituximab, radiation, and surgery. We present a case of an unusual morphologic variant of primary central nervous system PTLD with successful response to rituximab and cranial radiation. A 69-year-old Asian male, who underwent postrenal transplant nine years earlier, presented with a one-month history of new onset seizure activity. His evaluation revealed multiple brain lesions on magnetic resonance imaging (MRI), as well as serologic and cerebrospinal fluid studies which were positive for Epstein-Barr Virus (EBV) infection. Ultimately, he underwent craniotomy with tissue biopsy with the final pathology report showing posttransplant lymphoproliferative disorder, polymorphic type. The patient was managed with reduction in immunosuppression, rituximab therapy, and cranial radiation treatments. He had demonstrated marked improvement in his neurologic function and was ultimately discharged to inpatient rehabilitation facility. PMID:28116196

  8. A Rare Presentation of Isolated CNS Posttransplantation Lymphoproliferative Disorder.

    PubMed

    Morris, Jaime; Smith, Casey; Streicher, Andrew; Magnuson, Allison; Newman, Susan; Bertoli, Robert

    2017-01-01

    Posttransplantation lymphoproliferative disorder (PTLD) is a recognized and extremely morbid complication of solid organ transplantation, but central nervous system involvement, particularly in isolation, is rare. There are no standardized treatment strategies for PTLD, though commonly used strategies include reduction of immunosuppression, chemotherapy, rituximab, radiation, and surgery. We present a case of an unusual morphologic variant of primary central nervous system PTLD with successful response to rituximab and cranial radiation. A 69-year-old Asian male, who underwent postrenal transplant nine years earlier, presented with a one-month history of new onset seizure activity. His evaluation revealed multiple brain lesions on magnetic resonance imaging (MRI), as well as serologic and cerebrospinal fluid studies which were positive for Epstein-Barr Virus (EBV) infection. Ultimately, he underwent craniotomy with tissue biopsy with the final pathology report showing posttransplant lymphoproliferative disorder, polymorphic type. The patient was managed with reduction in immunosuppression, rituximab therapy, and cranial radiation treatments. He had demonstrated marked improvement in his neurologic function and was ultimately discharged to inpatient rehabilitation facility.

  9. Calibration techniques and results in the soft X-ray and extreme ultraviolet for components of the Extreme Ultraviolet Explorer Satellite

    NASA Technical Reports Server (NTRS)

    Malina, Roger F.; Jelinsky, Patrick; Bowyer, Stuart

    1986-01-01

    The calibration facilities and techniques for the Extreme Ultraviolet Explorer (EUVE) from 44 to 2500 A are described. Key elements include newly designed radiation sources and a collimated monochromatic EUV beam. Sample results for the calibration of the EUVE filters, detectors, gratings, collimators, and optics are summarized.

  10. Determination of the Solar Ultraviolet Transmission in Tree Shade.

    ERIC Educational Resources Information Center

    Parisi, Alfio V.; Kimlin, Michael G.

    1999-01-01

    Presents an activity in which the amount of solar ultraviolet radiation in tree shade is measured at different times of the day and compared with changes in illumination levels and temperature. (Author/WRM)

  11. Extreme ultraviolet spectra of multiply charged tungsten ions

    NASA Astrophysics Data System (ADS)

    Mita, Momoe; Sakaue, Hiroyuki A.; Kato, Daiji; Murakami, Izumi; Nakamura, Nobuyuki

    2017-11-01

    We present extreme ultraviolet spectra of multiply charged tungsten ions observed with an electron beam ion trap. The observed spectra are compared with previous experimental results and theoretical spectra obtained with a collisional radiative model.

  12. Modelling ultraviolet-line diagnostics of stars, the ionized and the neutral interstellar medium in star-forming galaxies

    NASA Astrophysics Data System (ADS)

    Vidal-García, A.; Charlot, S.; Bruzual, G.; Hubeny, I.

    2017-09-01

    We combine state-of-the-art models for the production of stellar radiation and its transfer through the interstellar medium (ISM) to investigate ultraviolet-line diagnostics of stars, the ionized and the neutral ISM in star-forming galaxies. We start by assessing the reliability of our stellar population synthesis modelling by fitting absorption-line indices in the ISM-free ultraviolet spectra of 10 Large Magellanic Cloud clusters. In doing so, we find that neglecting stochastic sampling of the stellar initial mass function in these young (∼10-100 Myr), low-mass clusters affects negligibly ultraviolet-based age and metallicity estimates but can lead to significant overestimates of stellar mass. Then, we proceed and develop a simple approach, based on an idealized description of the main features of the ISM, to compute in a physically consistent way the combined influence of nebular emission and interstellar absorption on ultraviolet spectra of star-forming galaxies. Our model accounts for the transfer of radiation through the ionized interiors and outer neutral envelopes of short-lived stellar birth clouds, as well as for radiative transfer through a diffuse intercloud medium. We use this approach to explore the entangled signatures of stars, the ionized and the neutral ISM in ultraviolet spectra of star-forming galaxies. We find that, aside from a few notable exceptions, most standard ultraviolet indices defined in the spectra of ISM-free stellar populations are prone to significant contamination by the ISM, which increases with metallicity. We also identify several nebular-emission and interstellar-absorption features, which stand out as particularly clean tracers of the different phases of the ISM.

  13. Broadband radiometer

    DOEpatents

    Cannon, Theodore W.

    1994-01-01

    A broadband radiometer including (a) an optical integrating sphere having a enerally spherical integrating chamber and an entry port for receiving light (e.g., having visible and ultraviolet fractions), (b) a first optical radiation detector for receiving light from the sphere and producing an electrical output signal corresponding to broadband radiation, (c) a second optical radiation detector for receiving light from the sphere and producing an electrical output signal corresponding to a predetermined wavelength fraction of the broadband radiation, and (d) an output for producing an electrical signal which is proportional to the difference between the two electrical output signals. The radiometer is very useful, for example, in measuring the absolute amount of ultraviolet light present in a given light sample.

  14. Broadband radiometer

    DOEpatents

    Cannon, T.W.

    1994-07-26

    A broadband radiometer is disclosed including (a) an optical integrating sphere having generally spherical integrating chamber and an entry port for receiving light (e.g., having visible and ultraviolet fractions), (b) a first optical radiation detector for receiving light from the sphere and producing an electrical output signal corresponding to broadband radiation, (c) a second optical radiation detector for receiving light from the sphere and producing an electrical output signal corresponding to a predetermined wavelength fraction of the broadband radiation, and (d) an output for producing an electrical signal which is proportional to the difference between the two electrical output signals. The radiometer is very useful, for example, in measuring the absolute amount of ultraviolet light present in a given light sample. 8 figs.

  15. Wavelength of ultraviolet radiation that enhances onset of clinical infectious bovine keratoconjunctivitis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kopecky, K.E.; Pugh, G.W. Jr.; Hughes, D.E.

    1980-09-01

    Cellulose acetate filtered ultraviolet (uv) radiation and unfiltered uv radiation were used on calves that were subsequently challenge exposed with Moraxella bovis. The onset, course, and severity of infectious bovine keratoconjunctivitis (IBK) were studied. Ten calves irradiated with unfiltered uv had the disease 1 to 2 days after M bovis challenge exposure. Ten calves irradiated with filtered uv and 10 calves not irradiated manifested IBK in a similar manner. Evidence is presented to support the contention that the wavelengths (around 270 nm) which are eliminated by cellulose acetate enhance the course of IBK. The effects on IBK of environmentally increasedmore » solar uv radiation is also discussed.« less

  16. Invest in sunblock

    NASA Astrophysics Data System (ADS)

    Carlowicz, Michael

    According to data gathered by the Total Ozone Mapping Spectrometer (TOMS) on NASA's Nimbus-7 satellite, the amount of ultraviolet radiation reaching the surface of Earth from the Sun has increased as the total amount of ozone in the atmosphere has decreased over the past 15 years.“The increases are largest in the middle and high latitudes, where most people live and most of the world's agricultural activity occurs,” said Jay Herman, an atmospheric scientist at NASA's Goddard Space Flight Center. According to Herman and colleagues, since 1978 the average annual exposure to ultraviolet B radiation (in the 290-320-nm range) has increased by 6.8% per decade at 55°N latitude, crossing the United Kingdom, Germany, Scandinavia, and Russia. At 55°S, cutting across southern Argentina and Chile, ultraviolet exposure increased 9.8% per decade. The change in UV-B radiation in most of North America was about 4% per decade.

  17. Increased exposure of Southern Ocean phytoplankton to ultraviolet radiation

    NASA Astrophysics Data System (ADS)

    Lubin, Dan; Arrigo, Kevin R.; van Dijken, Gert L.

    2004-05-01

    Satellite remote sensing of both surface solar ultraviolet radiation (UVR) and chlorophyll over two decades shows that biologically significant ultraviolet radiation increases began to occur over the Southern Ocean three years before the ozone ``hole'' was discovered. Beginning in October 1983, the most frequent occurrences of enhanced UVR over phytoplankton-rich waters occurred in the Weddell Sea and Indian Ocean sectors of the Southern Ocean, impacting 60% of the surface biomass by the late 1990s. These results suggest two reasons why more serious impacts to the base of the marine food web may not have been detected by field experiments: (1) the onset of UVR increases several years before dedicated field work began may have impacted the most sensitive organisms long before such damage could be detected, and (2) most biological field work has so far not taken place in Antarctic waters most extensively subjected to enhanced UVR.

  18. Anatomy of the Photodissociation Region in the Orion Bar

    NASA Technical Reports Server (NTRS)

    Tielens, A. G. G. M.; Meixner, M. M.; vanderWerf, P. P.; Bregman, J.; Tauber, J. A.; Stutzki, J.; Rank, D.

    1993-01-01

    Much of the interstellar gas resides in photodissociation regions whose chemistry and energy balance is controlled by the flux of far-ultraviolet radiation upon them. These photons can ionize and dissociate molecules and heat the gas through the photoelectric effect working on dust grains. These regions have been extensively modeled theoretically, but detailed observational studies are few. Mapping of the prominent Orion Bar photo-dissociation region at wavelengths corresponding to the carbon-hydrogen stretching mode of polycyclic aromatic hydrocarbons, the 1-0 S(l) line of molecular hydrogen, and the J = 1-0 rotational line of carbon monoxide allows the penetration of the far-ultraviolet radiation into the cloud to be traced. The results strongly support the theoretical models and show conclusively that the incident far-ultraviolet radiation field, not shocks as has sometimes been proposed, is responsible for the emission in the Orion Bar.

  19. Ultraviolet spectrometer experiment for the Voyager mission

    NASA Technical Reports Server (NTRS)

    Broadfoot, A. L.; Sandel, B. R.; Shemansky, D. E.; Atreya, S. K.; Donahue, T. M.; Moos, H. W.; Bertaux, J. L.; Blamont, J. E.; Ajello, J. M.; Strobel, D. F.

    1977-01-01

    An objective grating spectrometer covering the wavelength range of 500 to 1700 A with a 10-A resolution is employed for the Voyager ultraviolet spectrometer experiment. In determining the composition and structure of the atmospheres of Saturn, Jupiter and several satellites, the ultraviolet spectrometer will rely on airglow mode observations to measure radiation from the atmospheres due to resonant scattering of solar flux, and the occultation mode for assessments of the atmospheric extinction of solar or stellar radiation as the spacecraft enters shadow zones. Since it is capable of prolonged stellar observations in the 500 to 1000 A wavelength range, the spectrometer is expected to make important contributions to exploratory studies of UV sources.

  20. EFFECT OF ULTRA-VIOLET IRRADIATION OF RIBONUCLEIC ACID ON ITS CHROMATOGRAPHIC BEHAVIOUR

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kubinski, H.

    1963-11-01

    Experiments were made to illustrate the effects of ultraviolet radiation on RNA isolated from uninfected mammalian cells as well as those from those infected with polio virus. The chromatographic recovery of irradiated RNA, as judged by ultraviolet adsorbance and radioactivity (no plaque formers were found after irradiation), was considerably lower than that of unirradiated RNA. (P.C.H.)

  1. UV emissions from artificial tanning devices and their compliance with the European technical standard.

    PubMed

    Facta, Stefania; Fusette, Stefania Saudino; Bonino, Alessandro; Anglesio, Laura; d'Amore, Giovanni

    2013-04-01

    Use of ultraviolet radiation-emitting tanning devices has been classified as "carcinogenic to humans" (group 1) by the International Agency for Research on Cancer. Following this classification, the knowledge of typical ultraviolet emission levels from tanning devices can be of interest for evaluating their impact on health. In this work, the results of an extensive measurement campaign on artificial tanning appliances are presented. Ultraviolet emissions from 94 tanning appliances produced by 15 different manufacturers were characterized by onsite spectroradiometric measurements. The measured radiometric quantities were compared with reference values fixed in the European technical standard EN 60335-2-27 "Household and similar electrical appliances-Safety. Part 2: Particular requirements for appliances for skin exposure to ultraviolet and infrared radiation." Measurement results indicate that 88% of the examined appliances had ultraviolet emissions not compliant with the technical standard. Among the considered appliances, tanning devices equipped with low pressure lamps showed higher ultraviolet levels of effective irradiance and less compliance with standard requirements. In particular, UV emissions from 100% of low pressure appliances and from 78% of high pressure appliances exceeded the irradiance limit of 0.3 Wm set by the European technical standard.

  2. Influence of tropospheric ozone control on exposure to ultraviolet radiation at the surface.

    PubMed

    Madronich, Sasha; Wagner, Mark; Groth, Philip

    2011-08-15

    Improving air quality by reducing ambient ozone (O(3)) will likely lower O(3) concentrations throughout the troposphere and increase the transmission of solar ultraviolet (UV) radiation to the surface. The changes in surface UV radiation between two control scenarios (nominally 84 and 70 ppb O(3) for summer 2020) in the Eastern two-thirds of the contiguous U.S. are estimated, using tropospheric O(3) profiles calculated with a chemistry-transport model (Community Multi-Scale Air Quality, CMAQ) as inputs to a detailed model of the transfer of solar radiation through the atmosphere (tropospheric ultraviolet-visible, TUV) for clear skies, weighed for the wavelengths known to induce sunburn and skin cancer. Because the incremental emission controls differ according to region, strong spatial variability in O(3) reductions and in corresponding UV radiation increments is seen. The geographically averaged UV increase is 0.11 ± 0.03%, whereas the population-weighted increase is larger, 0.19 ± 0.06%, because O(3) reductions are greater in more densely populated regions. These relative increments in exposure are non-negligible given the already high incidence of UV-related health effects, but are lower by an order of magnitude or more than previous estimates.

  3. Replicated mesocosm study on the role of natural ultraviolet radiation in high CDOM, shallow lakes.

    PubMed

    Pérez, A Patricia; Diaz, Mónica M; Ferraro, Marcela A; Cusminsky, Gabriela C; Zagarese, Horacio E

    2003-02-01

    The role of ultraviolet radiation on shallow, high CDOM (colored dissolved organic matter) lakes was investigated during two consecutive summers (1999 and 2000) in replicated mesocosms (rectangular fiberglass tanks). Each tank (volume: 300 L; depth: 40 cm) was covered with a layer (approximately 3 cm) of sediment from lake El Toro (40 degrees 14' S; 70 degrees 22' W) and filled with filtered water. The experimental design consisted of two treatments: full natural radiation (UV-exposed) and natural radiation without ultraviolet radiation (UV-shielded). UV-exposed and UV-shielded treatments differed in most studied variables as revealed by repeated measures ANOVA. UV-exposed tanks displayed lower CDOM levels (dissolved absorbance) of lower average molecular size (absorbance ratio between 250 and 365 nm), higher bacterial biomass, and lower chlorophyll a concentration. The effect on consumers (rotifers and crustaceans) was less noticeable. The results are consistent with UV stimulation of bacteria production mediated by higher rates of CDOM photobleaching, and the photoinhibition of planktonic algae. Thus, a major effect of UVR in shallow, high CDOM ecosystems appears to be the stimulation of heterotrophic pathways and a simultaneous inhibition of photoautotrophs.

  4. Impact of plasma jet vacuum ultraviolet radiation on reactive oxygen species generation in bio-relevant liquids

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jablonowski, H.; Hammer, M. U.; Reuter, S.

    Plasma medicine utilizes the combined interaction of plasma produced reactive components. These are reactive atoms, molecules, ions, metastable species, and radiation. Here, ultraviolet (UV, 100–400 nm) and, in particular, vacuum ultraviolet (VUV, 10–200 nm) radiation generated by an atmospheric pressure argon plasma jet were investigated regarding plasma emission, absorption in a humidified atmosphere and in solutions relevant for plasma medicine. The energy absorption was obtained for simple solutions like distilled water (dH{sub 2}O) or ultrapure water and sodium chloride (NaCl) solution as well as for more complex ones, for example, Rosewell Park Memorial Institute (RPMI 1640) cell culture media. As moderate stablemore » reactive oxygen species, hydrogen peroxide (H{sub 2}O{sub 2}) was studied. Highly reactive oxygen radicals, namely, superoxide anion (O{sub 2}{sup •−}) and hydroxyl radicals ({sup •}OH), were investigated by the use of electron paramagnetic resonance spectroscopy. All species amounts were detected for three different treatment cases: Plasma jet generated VUV and UV radiation, plasma jet generated UV radiation without VUV part, and complete plasma jet including all reactive components additionally to VUV and UV radiation. It was found that a considerable amount of radicals are generated by the plasma generated photoemission. From the experiments, estimation on the low hazard potential of plasma generated VUV radiation is discussed.« less

  5. An investigation of solar erythemal ultraviolet radiation at two sites in tourist attraction areas of Thailand

    NASA Astrophysics Data System (ADS)

    Buntoung, Sumaman; Pattarapanitchai, Somjet; Wattan, Rungrat; Masiri, Itsara; Promsen, Worrapass; Tohsing, Korntip; Janjai, Serm

    2013-05-01

    Islands on the southern coasts of Thailand are famous attractions for local and foreign tourists. Tourists usually expose their skins to solar radiation for tanning. Thus information on solar ultraviolet radiation (UV) is of importance for tourists to protect themselves from adverse effects of UV. In this work, solar erythemal ultraviolet radiation (EUV) at two touristic sites namely Samui island (9.451°N, 100.033°E) and Phuket island (8.104°N, 98.304°E) was investigated. In investigating EUV, broadband UV radiometers (Kipp & Zonen, model UVS-B-C) were installed at existing meteorological stations in Samui and Phuket islands. A one-year period of EUV data from these two sites was analyzed. The level of UV index at these sites was studied. The values of UV index higher than 12 at noon time of clear days are usually found in the summer at both sites. Seasonal variation of EUV at both sites was investigated. It was found that the tropical monsoons have strong influence on this variation. Finally, global broadband radiation measured at the sites was also used to establish a correlation between EUV and global broadband radiation. Higher correlation was found for the case of clear sky, as compared to the case of cloudy sky. The correlation obtained from this analysis can be used to estimate EUV from global broadband radiation at these two sites.

  6. Changes in Optical Properties of Spacecraft Materials Due to Combined Effects of Aging Factors in a Space Environment

    DTIC Science & Technology

    2013-07-01

    display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) 16-07-2013 2...Bidirectional scattering distribution function (BSDF) and Bidirectional reflectance distribution function ( BRDF ) measurements were conducted for the...radiation (visible, ultraviolet, vacuum ultraviolet and soft X-ray radiation) at an altitude of 400 km 4) BSDF/ BRDF measurements have been conducted for

  7. Ethylene Decomposition Initiated by Ultraviolet Radiation from Low Pressure Mercury Lamps: Kinetics Model Prediction and Experimental Verification.

    NASA Astrophysics Data System (ADS)

    Jozwiak, Zbigniew Boguslaw

    1995-01-01

    Ethylene is an important auto-catalytic plant growth hormone. Removal of ethylene from the atmosphere surrounding ethylene-sensitive horticultural products may be very beneficial, allowing an extended period of storage and preventing or delaying the induction of disorders. Various ethylene removal techniques have been studied and put into practice. One technique is based on using low pressure mercury ultraviolet lamps as a source of photochemical energy to initiate chemical reactions that destroy ethylene. Although previous research showed that ethylene disappeared in experiments with mercury ultraviolet lamps, the reactions were not described and the actual cause of ethylene disappearance remained unknown. Proposed causes for this disappearance were the direct action of ultraviolet rays on ethylene, reaction of ethylene with ozone (which is formed when air or gas containing molecular oxygen is exposed to radiation emitted by this type of lamp), or reactions with atomic oxygen leading to formation of ozone. The objective of the present study was to determine the set of physical and chemical actions leading to the disappearance of ethylene from artificial storage atmosphere under conditions of ultraviolet irradiation. The goal was achieved by developing a static chemical model based on the physical properties of a commercially available ultraviolet lamp, the photochemistry of gases, and the kinetics of chemical reactions. The model was used to perform computer simulations predicting time dependent concentrations of chemical species included in the model. Development of the model was accompanied by the design of a reaction chamber used for experimental verification. The model provided a good prediction of the general behavior of the species involved in the chemistry under consideration; however the model predicted lower than measured rate of ethylene disappearance. Some reasons for the model -experiment disagreement are radiation intensity averaging, the experimental technique, mass transfer in the chamber, and incompleteness of the set of chemical reactions included in the model. The work is concluded with guidelines for development of a more complex mathematical model that includes elements of mass transfer inside the reaction chamber, and uses a three dimensional approach to distribute radiation from the low pressure mercury ultraviolet tube.

  8. Measurement of the solar ultraviolet radiation at ground level in Bangi, Malaysia

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aljawi, Ohoud; Gopir, Geri; Duay, Abdul Basit

    2015-04-24

    Understanding the amount of ultraviolet (UV) radiation received by human, plant, and animal organisms near the earth’s surface is important to a wide range of fields such as cancer research, agriculture and forestry. The solar ultraviolet spectral irradiance at ground level was measured using the Avantes spectrometer for the period of January to March 2014 at Bangi (2°55´N, 101°46´E, 50 m above sea level) in Malaysia. These data were used to estimate the diurnal variation of UV irradiance (300 – 400 nm). The maximum irradiance of UV radiation was 45 W m{sup −2} on horizontal surface. The maximum irradiance ofmore » UV received in the local noon time, and the minimum values of UV irradiance was received in the local morning time. It is found a bigger value of UV radiation was observed on clear sky in January. The estimation of daily flux average of UV irradiance was (921± 91) kJ m{sup −2}.« less

  9. Lanthanum (III) regulates the nitrogen assimilation in soybean seedlings under ultraviolet-B radiation.

    PubMed

    Huang, Guangrong; Wang, Lihong; Zhou, Qing

    2013-01-01

    Ultraviolet-B (UV-B, 280-320 nm) radiation has seriously affected the growth of plants. Finding the technology/method to alleviate the damage of UV-B radiation has become a frontal topic in the field of environmental science. The pretreatment with rare earth elements (REEs) is an effective method, but the regulation mechanism of REEs is unknown. Here, the regulation effects of lanthanum (La(III)) on nitrogen assimilation in soybean seedlings (Glycine max L.) under ultraviolet-B radiation were investigated to elucidate the regulation mechanism of REEs on plants under UV-B radiation. UV-B radiation led to the inhibition in the activities of the key enzymes (nitrate reductase, glutamine synthetase, glutamate synthase) in the nitrogen assimilation, the decrease in the contents of nitrate and soluble proteins, as well as the increase in the content of amino acid in soybean seedlings. The change degree of UV-B radiation at the high level (0.45 W m(-2)) was higher than that of UV-B radiation at the low level (0.15 W m(-2)). The pretreatment with 20 mg L(-1) La(III) could alleviate the effects of UV-B radiation on the activities of nitrate reductase, glutamine synthetase, glutamate synthase, and glutamate dehydrogenase, promoting amino acid conversion and protein synthesis in soybean seedlings. The regulation effect of La(III) under UV-B radiation at the low level was better than that of UV-B radiation at the high level. The results indicated that the pretreatment with 20 mg L(-1) La(III) could alleviate the inhibition of UV-B radiation on nitrogen assimilation in soybean seedlings.

  10. Photodamage: all signs lead to actinic keratosis and early squamous cell carcinoma.

    PubMed

    Wei, Jerry; Kok, Lai Fong; Byrne, Scott N; Halliday, Gary M

    2015-01-01

    Ultraviolet (UV) radiation is likely to drive the initiation and progression of skin cancer from actinic keratosis to squamous cell carcinoma. Signs of photodamage occur at multiple steps. UV radiation damages many cellular constituents, including lipids, proteins and DNA, all of which are likely to contribute to UV-induced skin cancer. Two biological events culminating from photodamage are mutations in the genes critical to the control of cell division, differentiation and invasion and immunosuppression. DNA photodamage, if unrepaired prior to cell division, can result in the incorporation of an incorrect nucleotide into newly synthesised DNA. Mutations in critical genes contribute to carcinogenesis. Photodamage to proteins such as those involved in DNA repair or proteins or lipids involved in cellular signalling can interfere with this repair process and contribute to mutagenesis. Mutations in key genes, including TP53, BRM, PTCH1, and HRAS, contribute to skin carcinogenesis. UV also damages immunity. Photodamage to DNA and signalling lipids as well as other molecular changes are detrimental to the key cells that regulate immunity. Photodamaged dendritic cells and altered responses by mast cells lead to the activation of T and B regulatory cells that suppress immunity to the protein products of UV-mutated genes. This stops the immune response from its protective function of destroying mutated cells, enabling the transformed cells to progress to skin cancer. UV appears to play a pivotal role at each of these steps, and therefore, signs of photodamage point to the development of skin cancer. © 2015 S. Karger AG, Basel.

  11. Good Afternoon, Sunshine! Protecting Children from Ultraviolet Rays.

    ERIC Educational Resources Information Center

    Certo, Delaine

    1996-01-01

    Notes caregivers' responsibility to protect children from too much exposure to ultraviolet radiation and the potential for melanoma. Provides suggestions on how to prevent children from sunburn and skin cancer, including the proper way to apply sunscreen. (MOK)

  12. 75 FR 21781 - Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ..., smallpox, yellow fever, viral hemorrhagic fevers, severe acute respiratory syndrome (SARS), and influenza... Proposed Changes to the Hospital Inpatient Prospective Payment Systems for Acute Care 0938-AP80 Hospitals... both ultraviolet B and ultraviolet A radiation protection. The last action addresses combination...

  13. Ultraviolet, visible, and infrared rays

    NASA Technical Reports Server (NTRS)

    Taylor, J. H.; Letavet, A. A.

    1975-01-01

    Sources of infrared, visible and ultraviolet radiation are discussed, and important associated biological and psychophysiological effects are described. The problem of protection from excessively high or low levels of radiant energy in these spectral regions is considered and optimal levels are suggested.

  14. 21 CFR 1040.20 - Sunlamp products and ultraviolet lamps intended for use in sunlamp products.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... irradiation of any part of the living human body, by ultraviolet radiation with wavelengths in air between 200..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) RADIOLOGICAL HEALTH PERFORMANCE STANDARDS FOR LIGHT...

  15. 21 CFR 1040.20 - Sunlamp products and ultraviolet lamps intended for use in sunlamp products.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... irradiation of any part of the living human body, by ultraviolet radiation with wavelengths in air between 200..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) RADIOLOGICAL HEALTH PERFORMANCE STANDARDS FOR LIGHT...

  16. Experimental investigation on large-area dielectric barrier discharge in atmospheric nitrogen and air assisted by the ultraviolet lamp.

    PubMed

    Zhang, Yan; Gu, Biao; Wang, Wenchun; Wang, Dezhen; Peng, Xuwen

    2009-04-01

    In this paper, ultraviolet radiation produced by the ultraviolet lamp is employed to supply pre-ionization for the dielectric barrier discharge in N(2) or air at atmospheric pressure. The effect of the ultraviolet pre-ionization on improving the uniformity of the dielectric barrier discharge is investigated experimentally. The atmospheric pressure glow discharge of the large area (270 mm x 120 mm) is obtained successfully via the ultraviolet pre-ionization in atmospheric DBD in N(2) when the gas gap decrease to 3mm. Based on the emission spectra, the mechanism which ultraviolet pre-ionization improves the uniformity of the dielectric barrier discharge is discussed.

  17. Nanotherapy of cancer by photoelectrons emitted from the surface of nanoparticles exposed to nonionizing ultraviolet radiation.

    PubMed

    Letfullin, Renat R; George, Thomas F

    2017-05-01

    We introduce a new method for selectively destroying cancer cell organelles by electrons emitted from the surface of intracellularly localized nanoparticles exposed to the nonionizing ultraviolet (UV) radiation. We propose to target cancerous intracellular organelles by nanoparticles and expose them to UV radiation with energy density safe for healthy tissue. We simulate the number of photoelectrons produced by the nanoparticles made of various metals and radii, calculate their kinetic energy and compare it to the threshold energy for producing biological damage. Exposure of metal nanoparticles to UV radiation generates photoelectrons with kinetic energies up to 11 eV, which is high enough to produce single- to double-strand breaks in the DNA and damage the cancerous cell organelles.

  18. Absolute measurement of undulator radiation in the extreme ultraviolet

    NASA Astrophysics Data System (ADS)

    Maezawa, H.; Mitani, S.; Suzuki, Y.; Kanamori, H.; Tamamushi, S.; Mikuni, A.; Kitamura, H.; Sasaki, T.

    1983-04-01

    The spectral brightness of undulator radiation emitted by the model PMU-1 incorporated in the SOR-RING, the dedicated synchrotron radiation source in Tokyo, has been studied in the extreme ultraviolet region from 21.6 to 72.9 eV as a function of the electron energy γ, the field parameter K, and the angle of observation ϴ in the absolute scale. A series of measurements covering the first and the second harmonic component of undulator radiation was compared with the fundamental formula λ n= {λ 0}/{2nγ 2}( {1+K 2}/{2}+γϴ 2 and the effects of finite emittance were studied. The brightness at the first peak was smaller than the theoretical value, while an enhanced second harmonic component was observed.

  19. Is the current public health message on UV exposure correct?

    PubMed Central

    Lucas, Robyn M.; Repacholi, Mike H.; McMichael, Anthony J.

    2006-01-01

    Current sun safety messages stress the importance of sun protection in avoiding the consequences of excessive exposure to ultraviolet radiation (UVR), such as skin cancers, cataracts and other eye diseases, and viral infections caused by UV-induced immunosuppression. However, adequate exposure to UVR has an important role in human health, primarily through UV-induced production of vitamin D, a hormone essential to bone health. Vitamin D insufficiency may be associated with increased risks of some cancers, autoimmune diseases and mental health disorders such as schizophrenia. Here, we review the evolution of current sun exposure practices and sun-safe messages and consider not only the benefits, but also the detrimental effects that such messages may have. UVR-induced vitamin D production can be inhibited by factors such as deep skin pigmentation, indoor lifestyles, older age, sun avoidance behaviours and clothing habits that limit skin exposure, with deleterious consequences for health. There is some early evidence that sun-safe messages are beginning to cause a decrease in skin cancer rates in young people. After the widespread promotion of sun safety, it may now be appropriate to refine public health messages to take better account of variations between groups and their susceptibility to the dangers and benefits of sun exposure. PMID:16799733

  20. The Skin Microbiome: Is It Affected by UV-induced Immune Suppression?

    PubMed Central

    Patra, VijayKumar; Byrne, Scott N.; Wolf, Peter

    2016-01-01

    Human skin apart from functioning as a physical barricade to stop the entry of pathogens, also hosts innumerable commensal organisms. The skin cells and the immune system constantly interact with microbes, to maintain cutaneous homeostasis, despite the challenges offered by various environmental factors. A major environmental factor affecting the skin is ultraviolet radiation (UV-R) from sunlight. UV-R is well known to modulate the immune system, which can be both beneficial and deleterious. By targeting the cells and molecules within skin, UV-R can trigger the production and release of antimicrobial peptides, affect the innate immune system and ultimately suppress the adaptive cellular immune response. This can contribute to skin carcinogenesis and the promotion of infectious agents such as herpes simplex virus and possibly others. On the other hand, a UV-established immunosuppressive environment may protect against the induction of immunologically mediated skin diseases including some of photodermatoses such as polymorphic light eruption. In this article, we share our perspective about the possibility that UV-induced immune suppression may alter the landscape of the skin’s microbiome and its components. Alternatively, or in concert with this, direct UV-induced DNA and membrane damage to the microbiome may result in pathogen associated molecular patterns (PAMPs) that interfere with UV-induced immune suppression. PMID:27559331

  1. Grape seed proanthocyanidines and skin cancer prevention: Inhibition of oxidative stress and protection of immune system

    PubMed Central

    Katiyar, Santosh K.

    2008-01-01

    Overexposure of the skin to ultraviolet (UV) radiation has a variety of adverse effects on human health, including the development of skin cancers. There is a need to develop nutrition-based efficient chemopreventive strategies. The proanthocyanidins present in grape seeds (Vitis vinifera) have been shown to have some biological effects, including prevention of photocarcinogenesis. The present communication discusses the in vitro and in vivo studies of the possible protective effect of grape seed proanthocyanidins (GSPs) and the molecular mechanism for these effects. In SKH-1 hairless mice, dietary supplementation with GSPs is associated with a decrease of UVB-induced skin tumor development in terms of tumor incidence, tumor multiplicity, and a decrease in the malignant transformation of papillomas to carcinomas. It is suggested that the chemopreventive effects of dietary GSPs are mediated through the attenuation of UV-induced: (a) oxidative stress; (b) activation of mitogen-activated protein kinases and nuclear factor-κB signaling pathways; and (c) immunosuppression through alterations in immunoregulatory cytokines. Collectively, these studies indicate protective potential of GSPs against experimental photocarcinogenesis in SKH-1 hairless mice, and the possible mechanisms of action of GSPs, and suggest that dietary GSPs could be useful in the attenuation of the adverse UV-induced health effects in human skin. PMID:18384090

  2. Epidermal PPARγ influences subcutaneous tumor growth and acts through TNF-α to regulate contact hypersensitivity and the acute photoresponse

    PubMed Central

    Konger, Raymond L.; Derr-Yellin, Ethel; Travers, Jeffrey B.; Ocana, Jesus A.; Sahu, Ravi P.

    2017-01-01

    It is known that ultraviolet B (UVB) induces PPARγ ligand formation while loss of murine epidermal PPARγ (Pparg-/-epi) promotes UVB-induced apoptosis, inflammation, and carcinogenesis. PPARγ is known to suppress tumor necrosis factor-α (TNF-α) production. TNF-α is also known to promote UVB-induced inflammation, apoptosis, and immunosuppression. We show that Pparg-/-epi mice exhibit increased baseline TNF-α expression. Neutralizing Abs to TNF-α block the increased photo-inflammation and photo-toxicity that is observed in Pparg-/-epi mouse skin. Interestingly, the increase in UVB-induced apoptosis in Pparg-/-epi mice is not accompanied by a change in cyclobutane pyrimidine dimer clearance or in mutation burden. This suggests that loss of epidermal PPARγ does not result in a significant alteration in DNA repair capacity. However, loss of epidermal PPARγ results in marked immunosuppression using a contact hypersensitivity (CHS) model. This impaired CHS response was significantly alleviated using neutralizing TNF-α antibodies or loss of germline Tnf. In addition, the PPARγ agonist rosiglitazone reversed UVB-induced systemic immunosuppression (UV-IS) as well as UV-induced growth of B16F10 melanoma tumor cells in syngeneic mice. Finally, increased B16F10 tumor growth was observed when injected subcutaneously into Pparg-/-epi mice. Thus, we provide novel evidence that epidermal PPARγ is important for cutaneous immune function and the acute photoresponse. PMID:29228682

  3. Molecular mechanisms of green tea polyphenols with protective effects against skin photoaging.

    PubMed

    Roh, Eunmiri; Kim, Jong-Eun; Kwon, Jung Yeon; Park, Jun Seong; Bode, Ann M; Dong, Zigang; Lee, Ki Won

    2017-05-24

    Whereas green tea has historically been consumed in high quantities in Northeast Asia, its popularity is also increasing in many Western countries. Green tea is an abundant source of plant polyphenols exhibiting numerous effects that are potentially beneficial for human health. Accumulating evidence suggests that green tea polyphenols confer protective effects on the skin against ultraviolet (UV) irradiation-induced acceleration of skin aging, involving antimelanogenic, antiwrinkle, antioxidant, and anti-inflammatory effects as well as prevention of immunosuppression. Melanin pigmentation in the skin is a major defense mechanism against UV irradiation, but pigmentation abnormalities such as melasma, freckles, senile lentigines, and other forms of melanin hyperpigmentation can also cause serious health and aesthetic issues. Furthermore, UV irradiation initiates the degradation of fibrillar collagen and elastic fibers, promoting the process of skin aging through deep wrinkle formation and loss of tissue elasticity. UV irradiation-induced formation of free radicals also contributes to accelerated photoaging. Additionally, immunosuppression caused by UV irradiation plays an important role in photoaging and skin carcinogenesis. In this review, we summarize the current literature regarding the antimelanogenic, antiwrinkle, antioxidant, and immunosuppression preventive mechanisms of green tea polyphenols that have been demonstrated to protect against UV irradiation-stimulated skin photoaging, and gauge the quality of evidence supporting the need for clinical studies using green tea polyphenols as anti-photoaging agents in novel cosmeceuticals.

  4. Space radiation resistant transparent polymeric materials

    NASA Technical Reports Server (NTRS)

    Giori, C.; Yamauchi, T.

    1977-01-01

    A literature search in the field of ultraviolet and charged particle irradiation of polymers was utilized in an experimental program aimed at the development of radiation stable materials for space applications. The rationale utilized for material selection and the synthesis, characterization and testing performed on several selected materials is described. Among the materials tested for ultraviolet stability in vacuum were: polyethyleneoxide, polyvinylnaphthalene, and the amino resin synthesized by the condensation of o-hydroxybenzoguanamine with formaldehyde. Particularly interesting was the radiation behavior of poly(ethyleneoxide), irradiation did not cause degradation of optical properties but rather an improvement in transparency as indicated by a decrease in solar absorptance with increasing exposure time.

  5. Average latitudinal variation in ultraviolet radiation at the earth's surface. [biological sensitivity and dosage

    NASA Technical Reports Server (NTRS)

    Johnson, F. S.; Mo, T.; Green, A. E. S.

    1976-01-01

    Tabulated values are presented for ultraviolet radiation at the earth's surface as a function of wavelength, latitude, and season, for clear sky and seasonally and latitudinally averaged ozone amounts. These tabulations can be combined with any biological sensitivity function in order to obtain the seasonal and latitudinal variation of the corresponding effective doses. The integrated dosages, based on the erythemal sensitivity curve and on the Robertson-Berger sunburn-meter sensitivity curve, have also been calculated, and these are found to vary with latitude and season in very nearly the same way as 307 and 314 nm radiation, respectively.

  6. DEMONSTRATION BULLETIN: CAV-OX ULTRAVIOLET OXIDATION PROCESS MAGNUM WATER TECHNOLOGY

    EPA Science Inventory

    The CAV-OX® technology (see Fig- ure 1) destroys organic contaminants, including chlorinated hy- drocarbons, in water. The process uses hydrogen peroxide, hy- drodynamic cavitation, and ultraviolet (UV) radiation to photolyze and oxidize organic compounds present in water at ...

  7. SUMER: Solar Ultraviolet Measurements of Emitted Radiation

    NASA Technical Reports Server (NTRS)

    Wilhelm, K.; Axford, W. I.; Curdt, W.; Gabriel, A. H.; Grewing, M.; Huber, M. C. E.; Jordan, S. D.; Kuehne, M.; Lemaire, P.; Marsch, E.

    1992-01-01

    The experiment Solar Ultraviolet Measurements of Emitted Radiation (SUMER) is designed for the investigations of plasma flow characteristics, turbulence and wave motions, plasma densities and temperatures, structures and events associated with solar magnetic activity in the chromosphere, the transition zone and the corona. Specifically, SUMER will measure profiles and intensities of Extreme Ultraviolet (EUV) lines emitted in the solar atmosphere ranging from the upper chromosphere to the lower corona; determine line broadenings, spectral positions and Doppler shifts with high accuracy, provide stigmatic images of selected areas of the Sun in the EUV with high spatial, temporal and spectral resolution and obtain full images of the Sun and the inner corona in selectable EUV lines, corresponding to a temperature from 10,000 to more than 1,800,000 K.

  8. Ultraviolet absorption experiment MA-059

    NASA Technical Reports Server (NTRS)

    Donahue, T. M.; Hudson, R. D.; Anderson, J.; Kaufman, F.; Mcelroy, M. B.

    1976-01-01

    The ultraviolet absorption experiment performed during the Apollo Soyuz mission involved sending a beam of atomic oxygen and atomic nitrogen resonance radiation, strong unabsorbable oxygen and nitrogen radiation, and visual radiation, all filling the same 3 deg-wide field of view from the Apollo to the Soyuz. The radiation struck a retroreflector array on the Soyuz and was returned to a spectrometer onboard the Apollo. The density of atomic oxygen and atomic nitrogen between the two spacecraft was measured by observing the amount of resonance radiation absorbed when the line joining Apollo and Soyuz was perpendicular to their velocity with respect to the ambient atmosphere. Information concerning oxygen densities was also obtained by observation of resonantly fluorescent light. The absorption experiments for atomic oxygen and atomic nitrogen were successfully performed at a range of 500 meters, and abundant resonance fluorescence data were obtained.

  9. Radiative lifetimes in B I using ultraviolet and vacuum-ultraviolet laser-induced fluorescence

    NASA Technical Reports Server (NTRS)

    O'Brian, T. R.; Lawler, J. E.

    1992-01-01

    Radiative lifetimes of the eight lowest even parity levels in the doublet system of B I are measured using time-resolved laser-induced fluorescence in the UV and VUV on an atomic beam of boron. The accurate lifetimes provide a base for improved determination of absolute transition probabilities in B I. The techniques described are broadly applicable to measurement of lifetimes of levels with transitions in the visible, UV, and VUV in almost any element.

  10. The creation of radiation dominated plasmas using laboratory extreme ultra-violet lasers

    NASA Astrophysics Data System (ADS)

    Tallents, G. J.; Wilson, S.; West, A.; Aslanyan, V.; Lolley, J.; Rossall, A. K.

    2017-06-01

    Ionization in experiments where solid targets are irradiated by high irradiance extreme ultra-violet (EUV) lasers is examined. Free electron degeneracy effects on ionization in the presence of a high EUV flux of radiation is shown to be important. Overlap of the physics of such plasmas with plasma material under compression in indirect inertial fusion is explored. The design of the focusing optics needed to achieve high irradiance (up to 1014 Wcm-2) using an EUV capillary laser is presented.

  11. Synchrotron Radiation II.

    ERIC Educational Resources Information Center

    MOSAIC, 1978

    1978-01-01

    Synchrotron radiation is a unique form of radiation that spans the electro-magnetic spectrum from X-rays through the ultraviolet and visible into the infrared. Tunable monochromators enable scientists to select a narrow band of wavelengths at any point in the spectrum. (Author/BB)

  12. Systematic identification of DNA variants associated with ultraviolet radiation using a novel Geographic-Wide Association Study (GeoWAS).

    PubMed

    Hsu, Irving; Chen, Rong; Ramesh, Aditya; Corona, Erik; Kang, Hyunseok Peter; Ruau, David; Butte, Atul J

    2013-06-20

    Long-term environmental variables are widely understood to play important roles in DNA variation. Previously, clinical studies examining the impacts of these variables on the human genome were localized to a single country, and used preselected DNA variants. Furthermore, clinical studies or surveys are either not available or difficult to carry out for developing countries. A systematic approach utilizing bioinformatics to identify associations among environmental variables, genetic variation, and diseases across various geographical locations is needed but has been lacking. Using a novel Geographic-Wide Association Study (GeoWAS) methodology, we identified Single Nucleotide Polymorphisms (SNPs) in the Human Genome Diversity Project (HGDP) with population allele frequencies associated geographical ultraviolet radiation exposure, and then assessed the diseases known to be assigned with these SNPs. 2,857 radiation SNPs were identified from over 650,000 SNPs in 52 indigenous populations across the world. Using a quantitative disease-SNP database curated from 5,065 human genetic papers, we identified disease associations with those radiation SNPs. The correlation of the rs16891982 SNP in the SLC45A2 gene with melanoma was used as a case study for analysis of disease risk, and the results were consistent with the incidence and mortality rates of melanoma in published scientific literature. Finally, by analyzing the ontology of genes in which the radiation SNPs were significantly enriched, potential associations between SNPs and neurological disorders such as Alzheimer's disease were hypothesized. A systematic approach using GeoWAS has enabled us to identify DNA variation associated with ultraviolet radiation and their connections to diseases such as skin cancers. Our analyses have led to a better understating at the genetic level of why certain diseases are more predominant in specific geographical locations, due to the interactions between environmental variables such as ultraviolet radiation and the population types in those regions. The hypotheses proposed in GeoWAS can lead to future testing and interdisciplinary research.

  13. Ultraviolet-Induced Decrease in Integration of Haemophilus influenzae Transforming Deoxyribonucleic Acid in Sensitive and Resistant Cells

    PubMed Central

    Muhammed, Amir; Setlow, Jane K.

    1970-01-01

    The decrease in integration of transforming deoxyribonucleic acid (DNA) caused by ultraviolet irradiation of the DNA was found to be independent of the presence or absence of excision repair in the recipient cell. Much of the ultraviolet-induced inhibition of integration resulted from the presence in the transforming DNA of pyrimidine dimers, as judged by the photoreactivability of the inhibition with yeast photoreactivating enzyme. The inhibition of integration made only a small contribution to the inactivation of transforming ability of the DNA by ultraviolet radiation. PMID:5308769

  14. Technology Evaluation Report - SITE PROGRAM DEMONSTRATION OF THE ULTROX INTERNATIONAL ULTRAVIOLET RADIATION OXIDATION TECHNOLOGY

    EPA Science Inventory

    In support of EPA's Superfund Innovative Technology Evaluation (SITE) Program, this report presents the results of the Ultrox International technology demonstration. The Ultrox® technology (a registered trademark of Ultrox International) simultaneously uses ultraviolet (UV) radi...

  15. Department of Health and Human Services Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ..., smallpox, yellow fever, viral hemorrhagic fevers, severe acute respiratory syndrome (SARS), and influenza... Proposed Changes to the Hospital Inpatient Prospective Payment Systems for Acute Care 0938-AP80 Hospitals... both ultraviolet B and ultraviolet A radiation protection. The last action addresses combination...

  16. Skyglow effects in UV and visible spectra: Radiative fluxes

    NASA Astrophysics Data System (ADS)

    Kocifaj, Miroslav; Solano Lamphar, Hector Antonio

    2013-09-01

    Several studies have tried to understand the mechanisms and effects of radiative transfer under different night-sky conditions. However, most of these studies are limited to the various effects of visible spectra. Nevertheless, the invisible parts of the electromagnetic spectrum can pose a more profound threat to nature. One visible threat is from what is popularly termed skyglow. Such skyglow is caused by injudiciously situated or designed artificial night lighting systems which degrade desired sky viewing. Therefore, since lamp emissions are not limited to visible electromagnetic spectra, it is necessary to consider the complete spectrum of such lamps in order to understand the physical behaviour of diffuse radiation at terrain level. In this paper, the downward diffuse radiative flux is computed in a two-stream approximation and obtained ultraviolet spectral radiative fluxes are inter-related with luminous fluxes. Such a method then permits an estimate of ultraviolet radiation if the traditionally measured illuminance on a horizontal plane is available. The utility of such a comparison of two spectral bands is shown, using the different lamp types employed in street lighting. The data demonstrate that it is insufficient to specify lamp type and its visible flux production independently of each other. Also the UV emissions have to be treated by modellers and environmental scientists because some light sources can be fairly important pollutants in the near ultraviolet. Such light sources can affect both the living organisms and ambient environment.

  17. New advances in protection against solar ultraviolet radiation in textiles for summer clothing.

    PubMed

    Aguilera, José; de Gálvez, María Victoria; Sánchez-Roldán, Cristina; Herrera-Ceballos, Enrique

    2014-01-01

    Clothing is considered one of the most important tools for photoprotection against harmful solar ultraviolet radiation (UVR). The standard for sun-protective clothing is based on erythema despite other biological effects of UVR on the skin. We analyzed the potential protection against UVR in fabrics destined for summer clothing based on several action spectra. We examined 50 garments classified by type of fabric composition, structure of the fiber yarn and color. The ultraviolet protection factor was calculated based on fabric ultraviolet transmittance corrected for erythema according to the EU standard E-13758 as well as the UVA transmittance of fabrics. UVR protection was also analyzed in base of different action spectra as for previtamin D3, nonmelanoma skin cancer, photoimmunosuppression and photoaging. Most knitted fabrics used for sports T-shirts offered excellent ratings for ultraviolet protection while normal shirts showed very low ratings, particularly against photoaging. The cover is the most influential variable in fabric photoprotection, having an exponential relationship with the UPF. The relation between cover and UVA protection was linearly negative. Information about ultraviolet protection in textiles used for summer clothing should be included in labeling as some types of fabrics, especially those used for shirts, offer very low UVR protection. © 2014 The American Society of Photobiology.

  18. [Effects of riboxin, essentiale, and phylloquinone on the immunomodulating and antioxidant effect of laser and magneto-laser irradiation in liver toxicosis induced by gentamycin].

    PubMed

    Konoplia, N A; Prokopenko, L G; Uteshev, B S

    2002-01-01

    The introduction of gentamycine to Wistar rats leads to the toxic liver damage, suppresses humoral immune response to goat erythrocytes, and induces immunosuppressant properties in erythrocytes (caused by increased lipid peroxidation in their membranes and violated cell energy balance) Under these conditions, a combination of the laser or magneto-laser irradiation with the administration of phylloquinone of riboxin provides for a more effective correction of the immune reaction and antioxidant status as compared to the radiation treatment without drugs or with essential. Elimination of the gentamycine induced immunosuppressant properties of erythrocytes is explained by the ability of phylloquinone and essential to reduce the intensity of lipid peroxidation in the cell membranes and with the ability of riboxin to normalize the cell energy balance. An important factor of immunosuppression development in the case of a toxic liver damage caused by D-galactosamine it the interaction of thrombocytes and light erythrocytes with serum factors. The introduction of essential and riboxin favors this interaction and stimulates the development of immunosuppression in thrombocytes.

  19. UV RADIATION EFFECTS ON MICROBES AND MICROBIAL PROCESSES

    EPA Science Inventory

    The ultraviolet (UV) region of solar radiation is defined as wavelengths in the range of 200 to 400 nm. In contrast to visible radiation (400 - 800 nm), which has a well-defined role as the energy source for most of the Earth's primary production, the effects of UV radiation on b...

  20. Characterization of a smartphone camera's response to ultraviolet A radiation.

    PubMed

    Igoe, Damien; Parisi, Alfio; Carter, Brad

    2013-01-01

    As part of a wider study into the use of smartphones as solar ultraviolet radiation monitors, this article characterizes the ultraviolet A (UVA; 320-400 nm) response of a consumer complementary metal oxide semiconductor (CMOS)-based smartphone image sensor in a controlled laboratory environment. The CMOS image sensor in the camera possesses inherent sensitivity to UVA, and despite the attenuation due to the lens and neutral density and wavelength-specific bandpass filters, the measured relative UVA irradiances relative to the incident irradiances range from 0.0065% at 380 nm to 0.0051% at 340 nm. In addition, the sensor demonstrates a predictable response to low-intensity discrete UVA stimuli that can be modelled using the ratio of recorded digital values to the incident UVA irradiance for a given automatic exposure time, and resulting in measurement errors that are typically less than 5%. Our results support the idea that smartphones can be used for scientific monitoring of UVA radiation. © 2012 Wiley Periodicals, Inc. Photochemistry and Photobiology © 2012 The American Society of Photobiology.

  1. Basal cell carcinoma of the eyelids and solar ultraviolet radiation exposure

    PubMed Central

    Lindgren, G.; Diffey, B.; Larko, O.

    1998-01-01

    AIMS—To compare the distribution of eyelid basal cell carcinoma (BCC) with the relative ultraviolet radiation (UVR) exposure to different sites on the eyelids.
METHODS—The location of BCC on the eyelids was allocated to one of seven regions. The UVR exposure was recorded with a polymer film attached to the eyelids at seven sites in a manikin and in human subjects.
RESULTS—Localisation of the 329 tumours was mainly on the lower eyelids (225 tumours), and the medial canthal regions (87 tumours). There was no association between UVR doses at the seven sites of the eyelids and the location of BCCs. The UVR exposure was similar on the upper and lower eyelids, while the number of tumours on the lower eyelids outnumbered the upper lids by a factor of 13 (17 upper, 225 lower)
CONCLUSION—UVR exposure only partially explains the aetiology of periorbital BCC.

 Keywords: polysulphone film; basal cell carcinoma; ultraviolet radiation; eyelid PMID:9930273

  2. UV RADIATION MEASUREMENTS/ATMOSPHERIC CHARACTERIZATION

    EPA Science Inventory

    Because exposure to ultraviolet (UV) radiation is an ecosystem stressor and poses a human health risk, the National Exposure Research Laboratory (NERL) has undertaken a research program to measure the intensity of UV-B radiation at various locations throughout the U.S. In Septem...

  3. Photoprotection beyond ultraviolet radiation--effective sun protection has to include protection against infrared A radiation-induced skin damage.

    PubMed

    Schroeder, P; Calles, C; Benesova, T; Macaluso, F; Krutmann, J

    2010-01-01

    Solar radiation is well known to damage human skin, for example by causing premature skin ageing (i.e. photoageing). We have recently learned that this damage does not result from ultraviolet (UV) radiation alone, but also from longer wavelengths, in particular near-infrared radiation (IRA radiation, 760-1,440 nm). IRA radiation accounts for more than one third of the solar energy that reaches human skin. While infrared radiation of longer wavelengths (IRB and IRC) does not penetrate deeply into the skin, more than 65% of the shorter wavelength (IRA) reaches the dermis. IRA radiation has been demonstrated to alter the collagen equilibrium of the dermal extracellular matrix in at least two ways: (a) by leading to an increased expression of the collagen-degrading enzyme matrix metalloproteinase 1, and (b) by decreasing the de novo synthesis of the collagen itself. IRA radiation exposure therefore induces similar biological effects to UV radiation, but the underlying mechanisms are substantially different, specifically, the cellular response to IRA irradiation involves the mitochondrial electron transport chain. Effective sun protection requires specific strategies to prevent IRA radiation-induced skin damage. 2010 S. Karger AG, Basel.

  4. Ultraviolet-radiation-induced methane emissions from meteorites and the Martian atmosphere.

    PubMed

    Keppler, Frank; Vigano, Ivan; McLeod, Andy; Ott, Ulrich; Früchtl, Marion; Röckmann, Thomas

    2012-05-30

    Almost a decade after methane was first reported in the atmosphere of Mars there is an intensive discussion about both the reliability of the observations--particularly the suggested seasonal and latitudinal variations--and the sources of methane on Mars. Given that the lifetime of methane in the Martian atmosphere is limited, a process on or below the planet's surface would need to be continuously producing methane. A biological source would provide support for the potential existence of life on Mars, whereas a chemical origin would imply that there are unexpected geological processes. Methane release from carbonaceous meteorites associated with ablation during atmospheric entry is considered negligible. Here we show that methane is produced in much larger quantities from the Murchison meteorite (a type CM2 carbonaceous chondrite) when exposed to ultraviolet radiation under conditions similar to those expected at the Martian surface. Meteorites containing several per cent of intact organic matter reach the Martian surface at high rates, and our experiments suggest that a significant fraction of the organic matter accessible to ultraviolet radiation is converted to methane. Ultraviolet-radiation-induced methane formation from meteorites could explain a substantial fraction of the most recently estimated atmospheric methane mixing ratios. Stable hydrogen isotope analysis unambiguously confirms that the methane released from Murchison is of extraterrestrial origin. The stable carbon isotope composition, in contrast, is similar to that of terrestrial microbial origin; hence, measurements of this signature in future Mars missions may not enable an unambiguous identification of biogenic methane.

  5. LOW PRESSURE ULTRAVIOLET STUDIES FOR INACTIVATION OF GIARDIA MURIS CYSTS

    EPA Science Inventory

    This research was initiated to confirm and expand the current database for the inactivation of Giardia spp. using ultraviolet (UV) radiation. Initially, previous research that used in vitro excystation as the indicator for UV effectiveness was confirmed. Later, the in vitro excys...

  6. Fruit and vegetable extracts as radiation protectants for the beet armyworm nucleopolyhedrovirus

    USDA-ARS?s Scientific Manuscript database

    Extracts from 37 fruits and vegetables were tested as ultraviolet (UV) protectants for the nucleopolyhedrovirus (SeMNPV) of the beet armyworm, Spodoptera exigua (Hübner) (Lepidoptera: Noctuidae). Only one extract (black currant) provided almost complete protection following ultraviolet B/ultraviole...

  7. The role of ultraviolet radiation in the pathogenesis of pterygia (Review).

    PubMed

    Zhou, Wei-Ping; Zhu, Yuan-Fang; Zhang, Bei; Qiu, Wen-Ya; Yao, Yu-Feng

    2016-07-01

    Pterygium is a common ophthalmic disease affecting humans only. Extensive epidemiological data have demonstrated a causative effect of chronic ultraviolet (UV) radiation on pterygia. Progress has been made in determining the origin of pterygia, their nasal predilection and wing‑shaped appearance, and the roles of UV radiation in the initiation and the development of pterygia. In the present review, the current understanding of the involvement of UV radiation in the pathogenesis of pterygia is summarized. This involvement includes the alteration of limbal stem cells and fibroblasts that contribute to the initiation of pterygia and the induction of various pro‑inflammatory cytokines, growth factors and matrix metalloproteinases that promote the progression of pterygia. Further elucidation of the roles of UV radiation in the pathogenesis of pterygia may help to encourage individuals at risk of developing pterygia to take preventive measures and aid researchers in the development of novel targeted therapeutic agents to treat pterygia.

  8. Invited Article: Refined analysis of synchrotron radiation for NIST's SURF III facility

    NASA Astrophysics Data System (ADS)

    Shirley, Eric L.; Furst, Mitchell; Arp, Uwe

    2018-04-01

    We have developed a new method for the exact calculation of synchrotron radiation for the National Institute of Standards and Technology Synchrotron Ultraviolet Radiation Facility, SURF III. Instead of using the Schwinger formula, which is only an approximation, we develop formulae based on Graf's addition theorem for Bessel functions and accurate asymptotic expansions for Hankel functions and Bessel functions. By measuring the radiation intensity profile at two distances from the storage ring, we also confirm an apparent vertical emittance that is consistent with the vertical betatron oscillations that are intentionally introduced to extend beam lifetime by spreading the electron beam spatially. Finally, we determine how much diffraction by beamline apertures enhances the spectral irradiance at an integrating sphere entrance port at the end station. This should eliminate small but treatable components of the uncertainty budget that one should consider when using SURF III or similar synchrotrons as standard, calculable sources of ultraviolet and other radiation.

  9. On the history of phyto-photo UV science (not to be left in skoto toto and silence).

    PubMed

    Björn, Lars Olof

    2015-08-01

    This review of the history of ultraviolet photobiology focuses on the effects of UV-B (280-315 nm) radiation on terrestrial plants. It describes the early history of ultraviolet photobiology, the discovery of DNA as a major ultraviolet target and the discovery of photoreactivation and photolyases, and the later identification of Photosystem II as another important target for damage to plants by UV-B radiation. Some experimental techniques are briefly outlined. The insight that the ozone layer was thinning spurred the interest in physiological and ecological effects of UV-B radiation and resulted in an exponential increase over time in the number of publications and citations until 1998, at which time it was realized by the research community that the Montreal Protocol regulating the pollution of the atmosphere with ozone depleting substances was effective. From then on, the publication and citation rate has continued to rise exponentially, but with an abrupt change to lower exponents. We have now entered a phase when more emphasis is put on the "positive" effects of UV-B radiation, and with more emphasis on regulation than on damage and inhibition. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  10. Red Fluorescent Line Emission from Hydrogen Molecules in Diffuse Molecular Clouds

    NASA Technical Reports Server (NTRS)

    Neufeld, David A.; Spaans, Marco

    1996-01-01

    We have modeled the fluorescent pumping of electronic and vibrational emissions of molecular hydrogen (H2) within diffuse molecular clouds that are illuminated by ultraviolet continuum radiation. Fluorescent line intensities are predicted for transitions at ultraviolet, infrared, and red visible wavelengths as functions of the gas density, the visual extinction through the cloud, and the intensity of the incident UV continuum radiation. The observed intensity in each fluorescent transition is roughly proportional to the integrated rate of H2 photodissociation along the line of sight. Although the most luminous fluorescent emissions detectable from ground-based observatories lie at near-infrared wavelengths, we argue that the lower sky brightness at visible wavelengths makes the red fluorescent transitions a particularly sensitive probe. Fabry-Perot spectrographs of the type that have been designed to observe very faint diffuse Ha emissions are soon expected to yield sensitivities that will be adequate to detect H2 vibrational emissions from molecular clouds that are exposed to ultraviolet radiation no stronger than the mean radiation field within the Galaxy. Observations of red H2 fluorescent emission together with cospatial 21 cm H I observations could serve as a valuable probe of the gas density in diffuse molecular clouds.

  11. Laser Desorption Postionization Mass Spectrometry of Antibiotic-Treated Bacterial Biofilms using Tunable Vacuum Ultraviolet Radiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gasper, Gerald L; Takahashi, Lynelle K; Zhou, Jia

    2010-08-04

    Laser desorption postionization mass spectrometry (LDPI-MS) with 8.0 ? 12.5 eV vacuum ultraviolet synchrotron radiation is used to single photon ionize antibiotics andextracellular neutrals that are laser desorbed both neat and from intact bacterial biofilms. Neat antibiotics are optimally detected using 10.5 eV LDPI-MS, but can be ionized using 8.0 eV radiation, in agreement with prior work using 7.87 eV LDPI-MS. Tunable vacuum ultraviolet radiation also postionizes laser desorbed neutrals of antibiotics and extracellular material from within intact bacterial biofilms. Different extracellular material is observed by LDPI-MS in response to rifampicin or trimethoprim antibiotic treatment. Once again, 10.5 eV LDPI-MSmore » displays the optimum trade-off between improved sensitivity and minimum fragmentation. Higher energy photons at 12.5 eV produce significant parent ion signal, but fragment intensity and other low mass ions are also enhanced. No matrix is added to enhance desorption, which is performed at peak power densities insufficient to directly produce ions, thus allowing observation of true VUV postionization mass spectra of antibiotic treated biofilms.« less

  12. Effects of polypeptide from Chlamys farreri on amino acid content in guinea pig skin irradiated by chronic ultraviolet A and B

    NASA Astrophysics Data System (ADS)

    Yu, Guoying; Cao, Pengli; Guo, Kun; Wang, Yuejun; Sun, Mi; Wang, Chunbo

    2004-12-01

    We examined the effects of polypeptide from Chlamys farreri (PCF) on the amount of hydroxyproline in guinea pig skin irradiated by chronic ultraviolet A (UVA) and ultraviolet B (UVB) radiation. PCF was applied locally before repeated exposure of guinea pig to UVA and UVB. The contents of hydroxyproline and other amino acids in guinea pig skin were determined by automatic amino acid analyzer. Our results showed that: (1) long-time UVA and UVB radiation can reduce dramatically the amounts of hydroxyproline, aspartic acid, threonine, glycine, phenylalanine and lysine in guinea pig skin in comparison with the control group ( P<0.05); (2) Compared with model group, pre-treatment with 5% and 20% PCF prior to UVA and UVB radiation can inhibit the decline of amino acids content in guinea pig skin in a dose-dependent manner ( P<0.05). As the decrease of hydroxyproline, glycine and lysine contents in the skin directly reflexes type I collagen degeneration, our results indicated that the chronic application of PCF can protect skin type I collagen against UV radiation, and thus protect skin from photoaging.

  13. INTERNAL FILTERS: PROSPECTS FOR UV-ACCLIMATION IN HIGHER PLANTS

    EPA Science Inventory

    Wavelength-selective absorption of solar radiation within plant leaves allows penetration of visible radiation (400-700nm) to the chloroplasts, while removing much of the damaging ultraviolet-B (UV-B, 280-320 nm) radiation. Flavonoids are important in this wavelength-selective ab...

  14. Generating circularly polarized radiation in the extreme ultraviolet spectral range at the free-electron laser FLASH

    NASA Astrophysics Data System (ADS)

    von Korff Schmising, Clemens; Weder, David; Noll, Tino; Pfau, Bastian; Hennecke, Martin; Strüber, Christian; Radu, Ilie; Schneider, Michael; Staeck, Steffen; Günther, Christian M.; Lüning, Jan; Merhe, Alaa el dine; Buck, Jens; Hartmann, Gregor; Viefhaus, Jens; Treusch, Rolf; Eisebitt, Stefan

    2017-05-01

    A new device for polarization control at the free electron laser facility FLASH1 at DESY has been commissioned for user operation. The polarizer is based on phase retardation upon reflection off metallic mirrors. Its performance is characterized in three independent measurements and confirms the theoretical predictions of efficient and broadband generation of circularly polarized radiation in the extreme ultraviolet spectral range from 35 eV to 90 eV. The degree of circular polarization reaches up to 90% while maintaining high total transmission values exceeding 30%. The simple design of the device allows straightforward alignment for user operation and rapid switching between left and right circularly polarized radiation.

  15. Radiation-damage-induced phasing: a case study using UV irradiation with light-emitting diodes.

    PubMed

    de Sanctis, Daniele; Zubieta, Chloe; Felisaz, Franck; Caserotto, Hugo; Nanao, Max H

    2016-03-01

    Exposure to X-rays, high-intensity visible light or ultraviolet radiation results in alterations to protein structure such as the breakage of disulfide bonds, the loss of electron density at electron-rich centres and the movement of side chains. These specific changes can be exploited in order to obtain phase information. Here, a case study using insulin to illustrate each step of the radiation-damage-induced phasing (RIP) method is presented. Unlike a traditional X-ray-induced damage step, specific damage is introduced via ultraviolet light-emitting diodes (UV-LEDs). In contrast to UV lasers, UV-LEDs have the advantages of small size, low cost and relative ease of use.

  16. The Role of Optical Radiations in Skin Cancer

    PubMed Central

    Palla, Marco; Di Trolio, Rossella; Mozzillo, Nicola; Ascierto, Paolo A.

    2013-01-01

    Purpose. Electromagnetic radiation with wavelength in the range 100 nm to 1 mm is known as optical radiation and includes ultraviolet radiation, the visible spectrum, and infrared radiation. The deleterious short- and long-term biological effects of ultraviolet radiation, including melanoma and other skin cancers, are well recognized. Infrared radiation may also have damaging biological effects. Methods. The objective of this review was to assess the literature over the last 15 years and to summarize correlations between exposure to optical radiation and the risk of melanoma and other cancers. Results. There is a clear correlation between exposure to UV radiation and the development of skin cancer. Most importantly, a strong association between artificial UV radiation exposure, for example, tanning devices, and the risk of melanoma and squamous cell carcinoma has been clearly demonstrated. There is no clear evidence that exposure to IR and laser radiation may increase the risk of skin cancer, although negative health effects have been observed. Conclusions. Preventative strategies that involve provision of public information highlighting the risks associated with exposure to sunlight remain important. In addition, precautionary measures that discourage exposure to tanning appliances are required, as is legislation to prevent their use during childhood. PMID:23710365

  17. Epstein-Barr virus and renal transplantation.

    PubMed

    Le, Jade; Durand, Christine M; Agha, Irfan; Brennan, Daniel C

    2017-01-01

    Epstein-Barr virus (EBV) is a gamma herpesvirus associated with diseases ranging from asymptomatic viremia to post-transplant malignancies in kidney transplant recipients. EBV specifically is associated with post-transplantation lymphoproliferative disorder (PTLD), in kidney transplant recipients, with increased risk in EBV seronegative patients with EBV seropositive donors on intensified immunosuppression. The diagnosis of PTLD relies on clinical suspicion plus tissue biopsy with polymerase chain reaction (PCR) testing of blood currently used for risk determination in high-risk recipients. Therapeutic strategies for PTLD include reduction of immunosuppression, chemotherapy and rituximab, and consideration of sirolimus-based immunosuppression. Antivirals such as ganciclovir are used to prevent reactivation of cytomegalovirus and other herpes viruses but are not onco-therapeutic. Radiation therapy or surgery is indicated for bulky, disseminated or recalcitrant disease. Prognosis varies depending on the type of malignancy identified and stage of disease. Copyright © 2016 Elsevier Inc. All rights reserved.

  18. The interaction of ultraviolet light with Arctic sea ice during SHEBA

    NASA Astrophysics Data System (ADS)

    Perovich, Donald K.

    The reflection, absorption and transmission of ultraviolet light by a sea-ice cover strongly impacts primary productivity, higher trophic components of the food web, and humans. Measurements of the incident irradiance at 305, 320, 340 and 380 nm and of the photosynthetically active radiation were made from April through September 1998 as part of the SHEBA (Surface Heat Budget of the Arctic Ocean program) field experiment in the Arctic Ocean. In addition, observations of snow depth and ice thickness were made at more than 100 sites encompassing a comprehensive range of conditions. The thickness observations were combined with a radiative transfer model to compute a time series of the ultraviolet light transmitted by the ice cover from April through September. Peak values of incident ultraviolet irradiance occurred in mid-June. Peak transmittance was later in the summer at the end of the melt season when the snow cover had completely melted, the ice had thinned and pond coverage was extensive. The fraction of the incident ultraviolet irradiance transmitted through the ice increased by several orders of magnitude as the melt season progressed. Ultraviolet transmittance was approximately a factor of ten greater for melt ponds than bare ice. Climate change has the potential to alter the amplitude and timing of the annual albedo cycle of sea ice. If the onset of melt occurs at increasingly earlier dates, ultraviolet transmittance will be significantly enhanced, with potentially deleterious biological impacts.

  19. Invisible Misconceptions: Student Understanding of Ultraviolet and Infrared Radiation

    ERIC Educational Resources Information Center

    Libarkin, Julie C.; Asghar, Anila; Crockett, C.; Sadler, Philip

    2011-01-01

    The importance of nonvisible wavelengths for the study of astronomy suggests that student understanding of nonvisible light is an important consideration in astronomy classrooms. Questionnaires, interviews, and panel discussions were used to investigate 6-12 student and teacher conceptions of ultraviolet (UV) and infrared (IR). Alternative…

  20. LOW PRESSURE ULTRAVIOLET STUDIES FOR INACTIVIATION OF GIARDIA MURIS CYSTS

    EPA Science Inventory

    This research was initiated to confirm and expand the current database for the inactiviation of Giardia spp. using ultraviolet (UV) radiation. The path taken was to confirm earlier UV research that used excystation as the indication of viability. In this study, an in vitro excyst...

  1. UV Radiation Damage and Bacterial DNA Repair Systems

    ERIC Educational Resources Information Center

    Zion, Michal; Guy, Daniel; Yarom, Ruth; Slesak, Michaela

    2006-01-01

    This paper reports on a simple hands-on laboratory procedure for high school students in studying both radiation damage and DNA repair systems in bacteria. The sensitivity to ultra-violet (UV) radiation of both "Escherichia coli" and "Serratia marcescens" is tested by radiating them for varying time periods. Two growth temperatures are used in…

  2. Comparison of Solar UVA and UVB Radiation Measured in Selangor, Malaysia

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kamarudin, S. U.; Gopir, G.; Yatim, B.

    The solar ultraviolet A (UVA) radiation data was measured at Physics Building, Universiti Kebangsaan Malaysia (2 degree sign 55' N, 101 degree sign 46' E, 50m asl) by the Xplorer GLX Pasco that connected to UVA Light sensor. The measured solar UVA data were compared with the total daily solar ultraviolet B (UVB) radiation data recorded by the Malaysian Metrological Department at Petaling Jaya, Malaysia (3 degree sign 06' N, 101 degree sign 39' E, 50m asl) for 18 days in year 2007. The daily total average of UVA radiation received is (298{+-}105) kJm{sup -2} while the total daily maximummore » is (600{+-}56) kJm{sup -2}. From the analysis, it shows that the values of UVA radiation data were higher than UVB radiation data with the average ratio of 6.41% between 3-14%. A weak positive correlation was found (the correlation coefficient, r, is 0.22). The amount of UVA radiation that reached the earth surface is less dependence on UVB radiation and the factors were discussed.« less

  3. EXPERIMENTS - APOLLO 17

    NASA Image and Video Library

    1972-11-17

    S72-53470 (November 1972) --- The Far-Ultraviolet Spectrometer, Experiment S-169, one of the lunar orbital science experiments which will be mounted in the SIM bay of the Apollo 17 Service Module. Controls for activating and deactivating the experiment and for opening and closing a protective cover are located in the Command Module. Atomic composition, density and scale height for several constituents of the lunar atmosphere will be measured by the far-ultraviolet spectrometer. Solar far-UV radiation reflected from the lunar surface as well as UV radiation emitted by galactic sources also will be detected by the instrument.

  4. Ultraviolet safety assessments of insect light traps.

    PubMed

    Sliney, David H; Gilbert, David W; Lyon, Terry

    2016-01-01

    Near-ultraviolet (UV-A: 315-400 nm), "black-light," electric lamps were invented in 1935 and ultraviolet insect light traps (ILTs) were introduced for use in agriculture around that time. Today ILTs are used indoors in several industries and in food-service as well as in outdoor settings. With recent interest in photobiological lamp safety, safety standards are being developed to test for potentially hazardous ultraviolet emissions. A variety of UV "Black-light" ILTs were measured at a range of distances to assess potential exposures. Realistic time-weighted human exposures are shown to be well below current guidelines for human exposure to ultraviolet radiation. These UV-A exposures would be far less than the typical UV-A exposure in the outdoor environment. Proposals are made for realistic ultraviolet safety standards for ILT products.

  5. THE EFFECT OF RADIATION ON ACETABULARIA. III. THE EFFECT OF X RADIATION AND ULTRAVIOLET RADIATION ON THE NUCLEATED PART OF ACETABULARIA MEDITERRANEA (in German)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Six, E.

    1958-01-01

    A study was made of the effect of x rays and ultraviolet radiation of various wave lengths on the nucleated cell part of Acetabularia mediterranea. The x radintion leads to a reduction of the regenerative capacity, to a decrease of cyst formation of the regenerated cells, and to a lowering of the viability of the cysts. After a dose of 400 hr the regenerative capacity is almost completely destroyed. The capacity for the formation of reproductive gametes is lost after 40 hr. The effect of UV irradiation is, on the other hand, much less. It was concluded that the observedmore » functions of the nucleated cell part are essentially determined by the nucleus, which in rhizoids is extensively shielded against UV radiation. A complete regeneration up to cap formation follows so size and shape of the full-grown regenerated cells do not appear to be influenced essertially by x radiation. (tr-auth)« less

  6. Randomized controlled trial of oral omega-3 PUFA in solar-simulated radiation-induced suppression of human cutaneous immune responses.

    PubMed

    Pilkington, Suzanne M; Massey, Karen A; Bennett, Susan P; Al-Aasswad, Naser Mi; Roshdy, Khaled; Gibbs, Neil K; Friedmann, Peter S; Nicolaou, Anna; Rhodes, Lesley E

    2013-03-01

    Skin cancer is a major public health concern, and the majority of cases are caused by solar ultraviolet radiation (UVR) exposure, which suppresses skin immunity. Omega-3 (n-3) PUFAs protect against photoimmunosuppression and skin cancer in mice, but the impact in humans is unknown. We hypothesized that EPA-rich n-3 PUFA would abrogate photoimmunosuppression in humans. Therefore, a nutritional study was performed to assess the effect on UVR suppression of cutaneous cell-mediated immunity (CMI) reflected by nickel contact hypersensitivity (CHS). In a double-blind, randomized controlled study, 79 volunteers (nickel-allergic women, 22-60 y old, with phototype I or II) took 5 g n-3 PUFA-containing lipid (70% EPA plus 10% DHA) or a control lipid daily for 3 mo. After supplementation, nickel was applied to 3 skin sites preexposed on 3 consecutive days to 1.9, 3.8, or 7.6 J/cm(2) of solar-simulated radiation (SSR) and to 3 unexposed control sites. Nickel CHS responses were quantified after 72 h and the percentage of immunosuppression by SSR was calculated. Erythrocyte [red blood cell (RBC)] EPA was measured by using gas chromatography. SSR dose-related suppression of the nickel CHS response was observed in both groups. Photoimmunosuppression appeared less in the n-3 PUFA group than in the control group (not statistically significant [mean difference (95% CI): 6.9% (-2.1%, 15.9%)]). The difference was greatest at 3.8 J/cm(2) SSR [mean difference: 11% (95% CI: 0.5%, 21.4%)]. Postsupplementation RBC EPA was 4-fold higher in the n-3 PUFA group than in the control group (mean difference: 2.69% (95% CI: 2.23%, 3.14%), which confirmed the EPA bioavailability. Oral n-3 PUFAs appear to abrogate photoimmunosuppression in human skin, providing additional support for their chemopreventive role; verification of study findings is required. This trial was registered at clinicaltrials.gov as NCT01032343.

  7. EFFECTS OF LABORATORY ULTRAVIOLET LIGHT AND NATURAL SUNLIGHT ON SURVIVAL AND DEVELOPMENT OF RANA PIPIENS

    EPA Science Inventory

    Changes in solar ultraviolet (UV) radiation have been proposed as a possible factor contributing to seeming increases in hindlimb malformations in anuran amphibians in North America. A primary purpose of this study was to reproduce results from an earlier experiment in which Ran...

  8. Urban tree influences on ultraviolet irradiance

    Treesearch

    Gordon M. Heisler; Richard H. Grant; Wei Gao

    2002-01-01

    Many of the effects of ultraviolet radiation (UVR) on people and their environment - damage to various materials, survival of insects and microbial pathogens, growth of vegetation, and adverse or beneficial effects on human health - are modified by the presence of trees. Human epidemiological investigations generally consider exposure as given by indices of UVR...

  9. Comparison of theory with atomic oxygen 130.4 nm radiation data from the Bow Shock ultraviolet 2 rocket flight

    NASA Technical Reports Server (NTRS)

    Levin, Deborah A.; Candler, Graham V.; Collins, Robert J.; Howlett, Carl L.; Espy, Patrick; Whiting, Ellis; Park, Chul

    1993-01-01

    Comparison is made between the results obtained from a state-of-the-art flow and radiative model and bow shock vacuum ultraviolet (VUV) data obtained the recent Bow Shock 2 Flight Experiment. An extensive data set was obtained from onboard rocket measurements at a reentry speed of 5 km/sec between the altitudes of approximately 65-85 km. A description of the NO photoionization cell used, the data, and the interpretation of the data will be presented. The primary purpose of the analyses is to assess the utility of the data and to propose a radiation model appropriate to the flight conditions of Bow Shock 2. Theoretical predictions based on flow modeling discussed in earlier work and a new radiation model are compared with data.

  10. Vulnerability and behavioral response to ultraviolet radiation in the components of a foliar mite prey-predator system.

    PubMed

    Tachi, Fuyuki; Osakabe, Masahiro

    2012-12-01

    Ambient ultraviolet-B (UVB) radiation impacts plant-dwelling arthropods including herbivorous and predatory mites. However, the effects of UVB on prey-predator systems, such as that between the herbivorous spider mite and predatory phytoseiid mite, are poorly understood. A comparative study was conducted to determine the vulnerability and behavioral responses of these mites to ultraviolet (UV) radiation. First, we analyzed dose-response (cumulative irradiance-mortality) curves for the eggs of phytoseiid mites (Neoseiulus californicus, Neoseiulus womersleyi, and Phytoseiulus persimilis) and the spider mite (Tetranychus urticae) to UVB radiation from a UV lamp. This indicated that the phytoseiid mites were more vulnerable than the spider mite, although P. persimilis was slightly more tolerant than the other two phytoseiid mites. Second, we compared the avoidance behavior of adult female N. californicus and two spider mite species (T. urticae, a lower leaf surface user; Panonychus citri, an upper leaf surface user) in response to solar UV and visible light. N. californicus actively avoided both types of radiation, whereas P. citri showed only minimal avoidance behavior. T. urticae actively avoided UV as well as N. californicus but exhibited a slow response to visible light as well as P. citri. Such variation in vulnerability and avoidance behavior accounts for differences in the species adaptations to solar UVB radiation. This may be the primary factor determining habitat use among these mites on host plant leaves, subsequently affecting accessibility by predators and also intraguild competition.

  11. Vulnerability and behavioral response to ultraviolet radiation in the components of a foliar mite prey-predator system

    NASA Astrophysics Data System (ADS)

    Tachi, Fuyuki; Osakabe, Masahiro

    2012-12-01

    Ambient ultraviolet-B (UVB) radiation impacts plant-dwelling arthropods including herbivorous and predatory mites. However, the effects of UVB on prey-predator systems, such as that between the herbivorous spider mite and predatory phytoseiid mite, are poorly understood. A comparative study was conducted to determine the vulnerability and behavioral responses of these mites to ultraviolet (UV) radiation. First, we analyzed dose-response (cumulative irradiance-mortality) curves for the eggs of phytoseiid mites ( Neoseiulus californicus, Neoseiulus womersleyi, and Phytoseiulus persimilis) and the spider mite ( Tetranychus urticae) to UVB radiation from a UV lamp. This indicated that the phytoseiid mites were more vulnerable than the spider mite, although P. persimilis was slightly more tolerant than the other two phytoseiid mites. Second, we compared the avoidance behavior of adult female N. californicus and two spider mite species ( T. urticae, a lower leaf surface user; Panonychus citri, an upper leaf surface user) in response to solar UV and visible light. N. californicus actively avoided both types of radiation, whereas P. citri showed only minimal avoidance behavior. T. urticae actively avoided UV as well as N. californicus but exhibited a slow response to visible light as well as P. citri. Such variation in vulnerability and avoidance behavior accounts for differences in the species adaptations to solar UVB radiation. This may be the primary factor determining habitat use among these mites on host plant leaves, subsequently affecting accessibility by predators and also intraguild competition.

  12. Temperature measurement using ultraviolet laser absorption of carbon dioxide behind shock waves.

    PubMed

    Oehlschlaeger, Matthew A; Davidson, David F; Jeffries, Jay B

    2005-11-01

    A diagnostic for microsecond time-resolved temperature measurements behind shock waves, using ultraviolet laser absorption of vibrationally hot carbon dioxide, is demonstrated. Continuous-wave laser radiation at 244 and 266 nm was employed to probe the spectrally smooth CO2 ultraviolet absorption, and an absorbance ratio technique was used to determine temperature. Measurements behind shock waves in both nonreacting and reacting (ignition) systems were made, and comparisons with isentropic and constant-volume calculations are reported.

  13. Radiation damage effects in far-ultraviolet filters, thin films, and substrates.

    PubMed

    Keffer, C E; Torr, M R; Zukic, M; Spann, J F; Torr, D G; Kim, J

    1994-09-01

    Advances in vacuum ultraviolet thin-film filter technology have been made through the use of filter designs with multilayers of materials such as Al(2)O(3), BaF(2), CaF(2), HfO(2), LaF(3), MgF(2), and SiO(2). Our immediate application for these filters will be in an imaging system to be flown on a satellite where a 2 × 9 R(E) orbit will expose the instrument to approximately 250 krad of radiation. Because to our knowledge no previous studies have been made on the potential radiation damage of these materials in the thin-film format, we report on such an assessment here. Transmittances and reflectances of BaF(2), CaF(2), HfO(2), MgF(2), and SiO(2) thin films on MgF(2) substrates, Al(2)O(3) thin films on fused-silica substrates, uncoated fused silica and MgF(2), and four multilayer filters made from these materials were measured from 120 to 180 nm beforeand after irradiation by 250 krad from a (60)Co gamma radiation source. No radiation-induced losses in transmittance or reflectance occurred in this wavelength range. Additional postradiation measurements from 160 to 300 nm indicates 2-5% radiation-induced absorption near 260 nm in some of the samples with MgF(2) substrates. From these measurements we conclude that far-ultraviolet filters made from the materials tested should experience less than 5% change from exposure to up to 250 krad of high-energy radiation in space applications.

  14. Spectral transmission of the pig lens: effect of ultraviolet A+B radiation.

    PubMed

    Artigas, C; Navea, A; López-Murcia, M-M; Felipe, A; Desco, C; Artigas, J-M

    2014-12-01

    To determine the spectral transmission curve of the crystalline lens of the pig. To analyse how this curve changes when the crystalline lens is irradiated with ultraviolet A+B radiation similar to that of the sun. To compare these results with literature data from the human crystalline lens. We used crystalline lenses of the common pig from a slaughterhouse, i.e. genetically similar pigs, fed with the same diet, and slaughtered at six months old. Spectral transmission was measured with a Perkin-Elmer Lambda 35 UV/VIS spectrometer. The lenses were irradiated using an Asahi Spectra Lax-C100 ultraviolet source, which made it possible to select the spectral emission band as well as the intensity and exposure time. The pig lens transmits all the visible spectrum (95%) and lets part of the ultraviolet A through (15%). Exposure to acute UV (A+B) irradiation causes a decrease in its transmission as the intensity or exposure time increases: this decrease is considerable in the UV region. We were able to determine the mean spectral transmission curve of the pig lens. It appears to be similar to that of the human lens in the visible spectrum, but different in the ultraviolet. Pig lens transmission is reduced by UV (A+B) irradiation and its transmission in the UV region can even disappear as the intensity or exposure time increases. An adequate exposure intensity and time of UV (A+B) radiation always causes an anterior subcapsular cataract (ASC). Copyright © 2014. Published by Elsevier Masson SAS.

  15. Ultraviolet radiation and nanoparticle induced intracellular free radicals generation measured in human keratinocytes by electron paramagnetic resonance spectroscopy.

    PubMed

    Rancan, F; Nazemi, B; Rautenberg, S; Ryll, M; Hadam, S; Gao, Q; Hackbarth, S; Haag, S F; Graf, C; Rühl, E; Blume-Peytavi, U; Lademann, J; Vogt, A; Meinke, M C

    2014-05-01

    Several nanoparticle-based formulations used in cosmetics and dermatology are exposed to sunlight once applied to the skin. Therefore, it is important to study possible synergistic effects of nanoparticles and ultraviolet radiation. Electron paramagnetic resonance spectroscopy (EPR) was used to detect intracellular free radicals induced by ultraviolet B (UVB) radiation and amorphous silica nanoparticle and to evaluate the influence of nanoparticle surface chemistry on particle cytotoxicity toward HaCaT cells. Uncoated titanium dioxide nanoparticles served as positive control. In addition, particle intracellular uptake, viability, and induction of interleukin-6 were measured. We found that photo-activated titanium dioxide particles induced a significant amount of intracellular free radicals. On the contrary, no intracellular free radicals were generated by the investigated silica nanoparticles in the dark as well as under UVB radiation. However, under UVB exposure, the non-functionalized silica nanoparticles altered the release of IL-6. At the same concentrations, the amino-functionalized silica nanoparticles had no influence on UVB-induced IL-6 release. EPR spectroscopy is a useful technique to measure nanoparticle-induced intracellular free radicals. Non-toxic concentrations of silica particles enhanced the toxicity of UVB radiation. This synergistic effect was not mediated by particle-generated free radicals and correlated with particle surface charge and intracellular distribution. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aguado, Alfredo; Roncero, Octavio; Zanchet, Alexandre

    The impact of the photodissociation of HCN and HNC isomers is analyzed in different astrophysical environments. For this purpose, the individual photodissociation cross sections of HCN and HNC isomers have been calculated in the 7–13.6 eV photon energy range for a temperature of 10 K. These calculations are based on the ab initio calculation of three-dimensional adiabatic potential energy surfaces of the 21 lower electronic states. The cross sections are then obtained using a quantum wave packet calculation of the rotational transitions needed to simulate a rotational temperature of 10 K. The cross section calculated for HCN shows significant differencesmore » with respect to the experimental one, and this is attributed to the need to consider non-adiabatic transitions. Ratios between the photodissociation rates of HCN and HNC under different ultraviolet radiation fields have been computed by renormalizing the rates to the experimental value. It is found that HNC is photodissociated faster than HCN by a factor of 2.2 for the local interstellar radiation field and 9.2 for the solar radiation field, at 1 au. We conclude that to properly describe the HNC/HCN abundance ratio in astronomical environments illuminated by an intense ultraviolet radiation field, it is necessary to use different photodissociation rates for each of the two isomers, which are obtained by integrating the product of the photodissociation cross sections and ultraviolet radiation field over the relevant wavelength range.« less

  17. Effects of Various Wavelength Ranges of Vacuum Ultraviolet Radiation on Teflon FEP Film Investigated

    NASA Technical Reports Server (NTRS)

    Dever, Joyce A.; McCracken, Cara A.

    2004-01-01

    Teflon Fluorinated Ethylene Propylene (FTP) films (DuPont) have been widely used for spacecraft thermal control and have been observed to become embrittled and cracked upon exposure to the space environment. This degradation has been attributed to a synergistic combination of radiation and thermal effects. A research study was undertaken at the NASA Glenn Research Center to examine the effects of different wavelength ranges of vacuum ultraviolet (VUV) radiation on the degradation of the mechanical properties of FEP. This will contribute to an overall understanding of space radiation effects on Teflon FEP, and will provide information necessary to determine appropriate techniques for using laboratory tests to estimate space VUV degradation. Research was conducted using inhouse facilities at Glenn and was carried out, in part, through a grant with the Cleveland State University. Samples of Teflon FEP film of 50.8 microns thickness were exposed to radiation from a VUV lamp from beneath different cover windows to provide different exposure wavelength ranges: MgF2 (115 to 400 nm), crystalline quartz (140 to 400 nm), and fused silica (FS, 155 to 400 nm). Following exposure, FEP film specimens were tensile tested to determine the ultimate tensile strength and elongation at failure as a function of the exposure duration for each wavelength range. The graphs show the effect of ultraviolet exposure on the mechanical properties of the FEP samples.

  18. Vacuum-ultraviolet lasers and spectroscopy

    NASA Astrophysics Data System (ADS)

    Hollenstein, U.

    2012-01-01

    Single-photon ionisation of most atoms and molecules requires short-wavelength radiation, typically in the vacuum-ultraviolet (VUV, λ < 200 nm) or extreme ultraviolet (XUV, λ < 105 nm) region of the electromagnetic spectrum. The first VUV and XUV radiation sources used to study molecular photoabsorption and photoionisation spectra were light sources emitting a broad continuous spectrum, such as high pressure lamps or synchrotrons. Monochromatic VUV and XUV radiation was obtained using diffraction gratings in evacuated monochromators, which resulted in a resolving power ν/Δv of at best 106 (i. e. 0.1 cm-1 at 100 000 cm-1), but more typically in the range 104-105 . The invention of the laser and the development of nonlinear optical frequency-upconversion techniques enabled the development of table-top narrow-bandwidth, coherent VUV and XUV laser sources with which VUV photoabsorption, photoionisation and photoelectron spectra of molecules can be recorded at much higher resolution, the best sources having bandwidths better than 50 MHz. Such laser sources are ideally suited to study the structure and dynamics of electronically excited states of atoms and molecules and molecular photoionisation using photoabsorption, photoionisation and photoelectron spectroscopy. This chapter presents the general principles that are exploited to generate tunable narrow-band laser radiation below 200 nm and describes spectroscopic methods such as photoabsorption spectroscopy, photoionisation spectroscopy and threshold photoelectron spectroscopy that relay on the broad tunability and narrow-bandwidth of VUV radiation sources.

  19. The endogenous hormones in soybean seedlings under the joint actions of rare earth element La(III) and ultraviolet-B stress.

    PubMed

    Peng, Qi; Zhou, Qing

    2009-12-01

    The dynamic state of endogenous hormone content in soybean seedlings was investigated for a further demonstration of alleviating the damage of the ultraviolet ultraviolet-B (UV-B) radiation in the La(III)-treated soybean seedlings under UV-B stress. Using hydroponics culture, the effects of lanthanum(III) on the contents of endogenous hormone under elevated ultraviolet-B radiation (280–320 nm) was studied. The results showed that the content of indole-3-acetic acid (IAA) in soybean seedlings decreased initially and then increased when the seedlings underwent UV-B treatment during the stress and convalescent period; this was compared with a control; acetic acid oxidase (IAAO) activity increased at first (first to fifth day) and then decreased (sixth to 11th day). A similar change of abscisic acid content and IAAO content in soybean seedlings occurred; gibberellic acid (GA) content decreased during the experiment compared with control. The content of IAA and GA in soybean seedlings with La(III) + UV-B treatment was higher than those of UV-B treatment; IAAO activity and GA content in soybean seedlings with La (III) + UV-B treatment were lower than those of UV-B treatment. It suggested that the regulative effect of La(III) at the optimum concentration on endogenous hormone improved the ability of plant stress resistance, and its protective effect against low UV-B radiation was superior to high UV-B radiation. The defensive effect of La(III) on soybean seedlings under UV-B stress was carried out on the layer of defense system.

  20. The effects of ionizing radiations on L-, DL-phenylalanine and L-, DL- tryptophase studied by ultra-violet and infra-red spectrophotometry

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Korgaonkar, K S; Donde, R B

    Aqueous solutions of L-, DL-phenylalanlne and L-, DLtryptophane were irradiated with Co 60 gamma rays. Marked changes in the ultraviolet spectra of the samples and in the infra-red spectra of their solid residues were noted. The radiosensitivities of these irradiated molecules in terms of G-values were determined, and the modes of action and the nature of irradiation products are discussed. A common order of radiosensitivities among the three aromatic amino acids both L-, and DL-forms is observed. Apparent differences In the ultraviolet spectral responses of tryptophane on the one hand and phenylalanine and tyrosine on the other are explained. Evidencemore » is presented suggesting some common radiation end-product of a cellulose or sugar type from these aromatic amino acids.« less

  1. The measurement of ultraviolet radiation and sunburn time over southern Ontario

    NASA Technical Reports Server (NTRS)

    Evans, W. F. J.

    1994-01-01

    Studies of the depletion of ozone which have been conducted from the TOMS instrument on the NIMBUS 7 satellite indicate that total ozone has declined by 5 percent over the last 12 years at most mid-latitudes in the Northern Hemisphere typical of southern Ontario. The measurement of the actual resultant increases in UVB is now important. A monitoring program of UVB (biologically active solar ultraviolet radiation) has been conducted for the last 24 months at a site near Bolton, Ontario. The sunburn time varies from less than 17 minutes in late July, to over 4 hours in December on clear days. The levels depend on solar insolation and total ozone column. The ultraviolet levels are strongly affected by cloud and sky conditions. The implications of present and future depletion on the sunburn time are discussed.

  2. Development of the Integrated Info Tech System

    DTIC Science & Technology

    2007-01-01

    withdrawn from the study:  Treatment with immunosuppressive  Cytotoxic  Corticosteroids  Anticoagulant agents such as Heparin, Plavix or Coumadin...such as Heparin, Plavix or Coumadin o Needing radiation or chemotherapy o Those who develop infection, Osteomyelitis, or dermatitis o At the

  3. Effects of near-ultraviolet light on mutations, intragenic and intergenic recombinations in Saccharomyces cerevisiae.

    PubMed

    Machida, I; Saeki, T; Nakai, S

    1986-03-01

    The effects of far (254 nm) and near (290-350 nm) ultraviolet (UV) light on mutations, intragenic and intergenic recombinations were compared in diploid strains of Saccharomyces cerevisiae. At equivalent survival levels there was not much difference in the induction of nonsense and missense mutations between far- and near-UV radiations. However, frameshift mutations were induced more frequently by near-UV than by far-UV radiation. Near-UV radiation induced intragenic recombination (gene conversion) as efficiently as far-UV radiation and the induced levels were similar in both radiations at equitoxic doses. A strikingly higher frequency was observed for the intergenic recombination induced by near-UV radiation than by far-UV radiation when compared at equivalent survival levels. Photoreactivation reduced the frequency only slightly in far-UV induced intergenic recombination and not at all in near-UV induction. These results indicate that near-UV damage involves strand breakage in addition to pyrimidine dimers and other lesions induced, whereas far-UV damage consists largely of photoreactivable lesions, pyrimidine dimers, and near-UV induced damage is more efficient for the induction of crossing-over.

  4. γ-H2AX formation in response to interstrand crosslinks requires XPF in human cells

    PubMed Central

    Mogi, Seiki; Oh, Dennis H.

    2009-01-01

    To further define the molecular mechanisms involved in processing interstrand crosslinks, we monitored the formation of phosphorylated histone H2AX (γ-H2AX), which is generated in chromatin near double strand break sites, following DNA damage in normal and repair-deficient human cells. Following treatment with a psoralen derivative and ultraviolet A radiation doses that produce significant numbers of crosslinks, γ-H2AX levels in nucleotide excision repair-deficient XP-A fibroblasts (XP12RO-SV) increased to levels that were twice those observed in normal control GM637 fibroblasts. A partial XPA revertant cell line (XP129) that is proficient in crosslink removal, exhibited reduced γ-H2AX levels that were intermediate between those of GM637 and XP-A cells. XP-F fibroblasts (XP2YO-SV and XP3YO) that are also repair-deficient exhibited γ-H2AX levels below even control fibroblasts following treatment with psoralen and ultraviolet A radiation. Similarly, another crosslinking agent, mitomycin C, did not induce γ-H2AX in XP-F cells, although it did induce equivalent levels of γ-H2AX in XPA and control GM637 cells. Ectopic expression of XPF in XP-F fibroblasts restored γ-H2AX induction following treatment with crosslinking agents. Angelicin, a furocoumarin which forms only monoadducts and not crosslinks following ultraviolet A radiation, as well as ultraviolet C radiation, resulted only in weak induction of γ-H2AX in all cells, suggesting that the double strand breaks observed with psoralen and ultraviolet A treatment result preferentially following crosslink formation. These results indicate that XPF is required to form γ-H2AX and likely double strand breaks in response to interstrand crosslinks in human cells. Furthermore, XPA may be important to allow psoralen interstrand crosslinks to be processed without forming a double strand break intermediate. PMID:16678501

  5. Flame Detector

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Scientific Instruments, Inc. has now developed a second generation, commercially available instrument to detect flames in hazardous environments, typically refineries, chemical plants and offshore drilling platforms. The Model 74000 detector incorporates a sensing circuit that detects UV radiation in a 100 degree conical field of view extending as far as 250 feet from the instrument. It operates in a bandwidth that makes it virtually 'blind' to solar radiation while affording extremely high sensitivity to ultraviolet flame detection. A 'windowing' technique accurately discriminates between background UV radiation and ultraviolet emitted from an actual flame, hence the user is assured of no false alarms. Model 7410CP is a combination controller and annunciator panel designed to monitor and control as many as 24 flame detectors. *Model 74000 is no longer being manufactured.

  6. Channel catfish response to ultraviolet-B radiation

    USGS Publications Warehouse

    Ewing, M.S.; Blazer, V.S.; Fabacher, D.L.; Little, E.E.; Kocan, K.M.

    1999-01-01

    Fingerling channel catfish Ictalurus punctatus exposed to simulated ultraviolet-B radiation at an average daily dose of 2.9 J/cm2 were quite sensitive to the radiation. After a 24-h exposure, thinning of the most dorsal epidermis frequently was accompanied by edema. Compared with epidermis of unexposed fish, mucous cells in exposed fish were less superficial and club cells were less numerous both dorsally and high on the lateral surface of the body. Sunburn cells with pyknotic nuclei were evident in the epidermis of exposed fish. Among fish exposed for 48 h, focal necrosis and sloughing of the outer epidermal layer were widespread. A methanol-extractable skin substance that is associated with resistance to sunburn in other fish species was not detected in channel catfish.

  7. Role of ultraviolet (UV) disinfection in infection control and environmental cleaning.

    PubMed

    Qureshi, Zubair; Yassin, Mohamed H

    2013-06-01

    Ultraviolet (UV) radiation is capable of disinfecting surfaces, water and air. The UV technology was used for many years. However, safer and more effective delivery systems of UV radiation, make it a very useful option for disinfection. Effective disinfection of environmental surfaces is a key step in the prevention of spread of infectious agents. The traditional manual cleaning is essential in assuring adequate elimination of contamination. However, terminal cleaning is frequently suboptimal or unpredictable in many circumstances. UV-C radiation is an adjunctive disinfectant new technology that could kill a wide array of microorganisms including both vegetative and spore forming pathogens. The technology is getting more affordable and has produced consistent reproducible significant reduction of bacterial contamination.

  8. Ultraviolet disinfection of water for small water supplies

    NASA Astrophysics Data System (ADS)

    Carlson, D. A.; Seabloom, R. W.; Dewalle, F. B.; Wetzler, T. F.; Engeset, J.

    1985-07-01

    In the study ultraviolet radiation was considered as an alternative means of disinfection of small drinking water supplies. A major impetus for the study was the large increase in waterborne disease episodes in the United States whose etiologic agent, Giardia lamblia, was found to be highly resistant to conventional chlorination. While the germicidal effect of sunlight has long been known, it has been found that artificial UV radiation with a wavelength of 253.7 nm, can be produced by low pressure mercury vapor lamps. The inactivation of microorganisms by UV radiation is based upon photochemical reactions in DNA which result in errors in the coding system. Inactivation of microorganisms due to exposure to UV is proportional to the intensity multiplied by the time of exposure.

  9. UV clothing and skin cancer.

    PubMed

    Tarbuk, Anita; Grancarić, Ana Marija; Situm, Mirna; Martinis, Mladen

    2010-04-01

    Skin cancer incidence in Croatia is steadily increasing in spite of public and governmental permanently measurements. It is clear that will soon become a major public health problem. The primary cause of skin cancer is believed to be a long exposure to solar ultraviolet (UV) radiation. The future designers of UV protective materials should be able to block totally the ultraviolet radiation. The aim of this paper is to present results of measurements concerning UV protecting ability of garments and sun-screening textiles using transmission spectrophotometer Cary 50 Solarscreen (Varian) according to AS/NZS 4399:1996; to show that standard clothing materials are not always adequate to prevent effect of UV radiation to the human skin; and to suggest the possibilities for its improvement for this purpose.

  10. Impact of shortwave ultraviolet (UV-C) radiation on the antioxidant activity of thyme (Thymus vulgaris L.).

    PubMed

    Dogu-Baykut, Esra; Gunes, Gurbuz; Decker, Eric Andrew

    2014-08-15

    Thyme is a good source of antioxidant compounds but it can be contaminated by microorganisms. An experimental fluid bed ultraviolet (UV) reactor was designed for microbial decontamination of thyme samples and the effect of shortwave ultraviolet light (UV-C) radiation on antioxidant properties of thyme was studied. Samples were exposed to UV-C radiation for 16 or 64 min. UV-C treatment led to 1.04 and 1.38 log CFU/g reduction of total aerobic mesophilic bacteria (TAMB) counts. Hunter a(∗) value was the most sensitive colour parameter during UV-C treatment. 2,2-Diphenyl-1-picrylhydrazyl (DPPH) scavenging activity of extracts was not significantly affected by UV-C. Addition of thyme extracts at 0.15 and 0.3 μmol GAE/ml emulsion delayed the formation of lipid hydroperoxides and headspace hexanal in the 5.0%(wt) corn oil-in-water emulsion from 4 to 9 and 14 days, respectively. No significant changes in oxidation rates were observed between UV-C treated and untreated samples at same concentrations. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. Variation and Grey GM(1, 1) Prediction of Melting Peak Temperature of Polypropylene During Ultraviolet Radiation Aging

    NASA Astrophysics Data System (ADS)

    Chen, K.; Y Zhang, T.; Zhang, F.; Zhang, Z. R.

    2017-12-01

    Grey system theory regards uncertain system in which information is known partly and unknown partly as research object, extracts useful information from part known, and thereby revealing the potential variation rule of the system. In order to research the applicability of data-driven modelling method in melting peak temperature (T m) fitting and prediction of polypropylene (PP) during ultraviolet radiation aging, the T m of homo-polypropylene after different ultraviolet radiation exposure time investigated by differential scanning calorimeter was fitted and predicted by grey GM(1, 1) model based on grey system theory. The results show that the T m of PP declines with the prolong of aging time, and fitting and prediction equation obtained by grey GM(1, 1) model is T m = 166.567472exp(-0.00012t). Fitting effect of the above equation is excellent and the maximum relative error between prediction value and actual value of T m is 0.32%. Grey system theory needs less original data, has high prediction accuracy, and can be used to predict aging behaviour of PP.

  12. Prevalence and determinants of Australian adolescents' and adults' weekend sun protection and sunburn, summer 2003-2004.

    PubMed

    Dobbinson, Suzanne; Wakefield, Melanie; Hill, David; Girgis, Afaf; Aitken, Joanne F; Beckmann, Kerri; Reeder, Anthony I; Herd, Natalie; Fairthorne, Andrew; Bowles, Kelly-Ann

    2008-10-01

    Reducing people's exposure to ultraviolet radiation is the primary strategy for skin cancer prevention. We sought to provide comprehensive national data on preventive behaviors and risk assessment for Australia. A national survey was conducted in summer 2003-2004. In 8 weekly cross-sectional surveys, adults and adolescents were interviewed about their sun protection and sunburn on the previous summer weekend. Adjustments were made for specific weather and ultraviolet radiation conditions relevant to time and location. Adolescents were relatively homogeneous in their low compliance with sun protection (significantly less use of hats, covering clothing, shade, and sunglasses than adults) on weekends, and consequently were more likely to be sunburned than adults (25% compared with 18%; odds ratio=1.80, P<.001). Temperature was a significant predictor of sun-protective behaviors and a strong determinant of sunburn, as was ultraviolet radiation for adults' sunburn. Using shade, spending less time outdoors, and, for adults, wearing clothing covering were associated with reduced odds of sunburn. The study relied on self-reported behaviors and sunburn. Further improvement in Australians' sun-protective behaviors is needed.

  13. Tunable, rare earth-doped solid state lasers

    DOEpatents

    Emmett, John L.; Jacobs, Ralph R.; Krupke, William F.; Weber, Marvin J.

    1980-01-01

    Laser apparatus comprising combinations of an excimer pump laser and a rare earth-doped solid matrix, utilizing the 5d-4f radiative transition in a rare earth ion to produce visible and ultra-violet laser radiation with high overall efficiency in selected cases and relatively long radiative lifetimes.

  14. Ultraviolet safety assessments of insect light traps

    PubMed Central

    Sliney, David H.; Gilbert, David W.; Lyon, Terry

    2016-01-01

    ABSTRACT Near-ultraviolet (UV-A: 315–400 nm), “black-light,” electric lamps were invented in 1935 and ultraviolet insect light traps (ILTs) were introduced for use in agriculture around that time. Today ILTs are used indoors in several industries and in food-service as well as in outdoor settings. With recent interest in photobiological lamp safety, safety standards are being developed to test for potentially hazardous ultraviolet emissions. A variety of UV “Black-light” ILTs were measured at a range of distances to assess potential exposures. Realistic time-weighted human exposures are shown to be well below current guidelines for human exposure to ultraviolet radiation. These UV-A exposures would be far less than the typical UV-A exposure in the outdoor environment. Proposals are made for realistic ultraviolet safety standards for ILT products. PMID:27043058

  15. Observations of the Ultraviolet Spectra of Helium (DB) White Dwarfs and a Study of the Ultraviolet Spectra of White Dwarfs Containing Carbon

    NASA Technical Reports Server (NTRS)

    Wegner, G. A.

    1984-01-01

    Strong ultraviolet carbon lines were detected in the spectrum of the southern DC white dwarf BPM 11668. Observations of a number of hotter DB white dwarfs with IUE show no evidence of carbon features. Two additional DA white dwarfs were observed that have the strong unidentified absorption near 1400 A which now seems to be identified with another lower temperature feature as satellite lines to Lyman alpha radiation.

  16. Ultraviolet Source For Testing Hydrogen-Fire Detectors

    NASA Technical Reports Server (NTRS)

    Hall, Gregory A.; Larson, William E.; Youngquist, Robert C.; Moerk, John S.; Haskell, William D.; Cox, Robert B.; Polk, Jimmy D.; Stout, Stephen J.; Strobel, James P.

    1995-01-01

    Hand-held portable unit emits ultraviolet light similar to that emitted by hydrogen burning in air. Developed for use in testing optoelectronic hydrogen-fire detectors, which respond to ultraviolet light at wavelengths from 180 to 240 nanometers. Wavelength range unique in that within it, hydrogen fires emit small but detectable amounts of radiation, light from incandescent lamps and Sun almost completely absent, and air sufficiently transmissive to enable detection of hydrogen fire from distance. Consequently, this spectral region favorable for detecting hydrogen fires while minimizing false alarms.

  17. The contributions of solar ultraviolet radiation exposure and other determinants to serum 25-hydroxyvitamin D concentrations in Australian adults: the AusD Study.

    PubMed

    Kimlin, Michael G; Lucas, Robyn M; Harrison, Simone L; van der Mei, Ingrid; Armstrong, Bruce K; Whiteman, David C; Kricker, Anne; Nowak, Madeleine; Brodie, Alison M; Sun, Jiandong

    2014-04-01

    The Quantitative Assessment of Solar UV [ultraviolet] Exposure for Vitamin D Synthesis in Australian Adults (AusD) Study aimed to better define the relationship between sun exposure and serum 25-hydroxyvitamin D (25(OH)D) concentration. Cross-sectional data were collected between May 2009 and December 2010 from 1,002 participants aged 18-75 years in 4 Australian sites spanning 24° of latitude. Participants completed the following: 1) questionnaires on sun exposure, dietary vitamin D intake, and vitamin D supplementation; 2) 10 days of personal ultraviolet radiation dosimetry; 3) a sun exposure and physical activity diary; and 4) clinical measurements and blood collection for 25(OH)D determination. Our multiple regression model described 40% of the variance in 25(OH)D concentration; modifiable behavioral factors contributed 52% of the explained variance, and environmental and demographic or constitutional variables contributed 38% and 10%, respectively. The amount of skin exposed was the single strongest contributor to the explained variance (27%), followed by location (20%), season (17%), personal ultraviolet radiation exposure (8%), vitamin D supplementation (7%), body mass index (weight (kg)/height (m)(2)) (4%), and physical activity (4%). Modifiable behavioral factors strongly influence serum 25(OH)D concentrations in Australian adults. In addition, latitude was a strong determinant of the relative contribution of different behavioral factors.

  18. Viability of Cladosporium herbarum spores under 157 nm laser and vacuum ultraviolet irradiation, low temperature (10 K) and vacuum

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sarantopoulou, E., E-mail: esarant@eie.gr; Stefi, A.; Kollia, Z.

    Ultraviolet photons can damage microorganisms, which rarely survive prolonged irradiation. In addition to the need for intact DNA, cell viability is directly linked to the functionality of the cell wall and membrane. In this work, Cladosporium herbarum spore monolayers exhibit high viability (7%) when exposed to 157 nm laser irradiation (412 kJm⁻²) or vacuum-ultraviolet irradiation (110–180 nm) under standard pressure and temperature in a nitrogen atmosphere. Spore viability can be determined by atomic-force microscopy, nano-indentation, mass, μ-Raman and attenuated reflectance Fourier-transform far-infrared spectroscopies and DNA electrophoresis. Vacuum ultraviolet photons cause molecular damage to the cell wall, but radiation resistance inmore » spores arises from the activation of a photon-triggered signaling reaction, expressed via the exudation of intracellular substances, which, in combination with the low penetration depth of vacuum-ultraviolet photons, shields DNA from radiation. Resistance to phototoxicity under standard conditions was assessed, as was resistance to additional environmental stresses, including exposure in a vacuum, under different rates of change of pressure during pumping time and low (10 K) temperatures. Vacuum conditions were far more destructive to spores than vacuum-ultraviolet irradiation, and UV-B photons were two orders of magnitude more damaging than vacuum-ultraviolet photons. The viability of irradiated spores was also enhanced at 10 K. This work, in addition to contributing to the photonic control of the viability of microorganisms exposed under extreme conditions, including decontamination of biological warfare agents, outlines the basis for identifying bio-signaling in vivo using physical methodologies.« less

  19. ADVANCED OXIDATION PROCESS TECHNOLOGY (ULTRAVIOLET RADIATION/OZONE TREATMENT) FOR REMOVAL OF METHYL TERTIARY BUTYL ETHER (MTBE) IN GROUND WATER SUPPLIES.

    EPA Science Inventory

    U.S. EPA’s Office of Research and Development in Cincinnati, Ohio has been testing and evaluating MTBE removal in dechlorinated tap water using three oxidant combinations: hydrogen peroxide/ozone, ultraviolet irradiation (UV)/ozone, and UV/ozone/hydrogen peroxide. Pilot-scale st...

  20. Spatial and Temporal Variability of Solar Ultraviolet Exposure of Coral Assemblages in the Florida Keys: Importance of Colored Dissolved Organic Matter x

    EPA Science Inventory

    Solar ultraviolet (UV) radiation can have deleterious effects on coral assemblages in tropical and subtropical marine environments, but little information is available on UV penetration into ocean waters surrounding corals. Here we provide an extensive data set of optical propert...

  1. Ferroelectric Thin-Film Capacitors As Ultraviolet Detectors

    NASA Technical Reports Server (NTRS)

    Thakoor, Sarita

    1995-01-01

    Advantages include rapid response, solar blindness, and relative invulnerability to ionizing radiation. Ferroelectric capacitor made to function as photovoltaic detector of ultraviolet photons by making one of its electrodes semitransparent. Photovoltaic effect exploited more fully by making Schottky barrier at illuminated semitransparent-electrode/ferroelectric interface taller than Schottky barrier at other electrode/ferroelectric interface.

  2. Individual- and scattered-tree influences on ultraviolet irradiance

    Treesearch

    Gordon M. Heisler; Richard H. Gao, Wei Grant

    2003-01-01

    Many of the potential effects of ultraviolet radiation (UVR--damage to materials, altered herbivory of insects and activity of microbes, modified growth of vegetation, and adverse or beneficial effects on human health?are modified by the presence of trees that influence UVR exposure to various degrees. Though tree effects on total solar irradiance have been...

  3. Solar Electromagnetic Radiation Study for Solar Cycle 22: Solar Ultraviolet Irradiance, 120 to 300 NM: Report of Working Groups 2 and 3 of SOLERS 22

    NASA Technical Reports Server (NTRS)

    Rottman, G. J.; Cebula, R. P.; Gillotay, D.; Simon, P. A.

    1996-01-01

    This report summarizes the activities of Working Group 2 and Working Group 3 of the SOLax Electromagnetic Radiation Study for Solar Cycle 22 (SOLERS22) Program. The international (SOLERS22) is Project 1.2 of the Solar-Terrestrial Energy Program (STEP) sponsored by SCOSTEP, a committee of the International Council of Scientific Unions). SOLERS22 is comprised of five Working Groups, each concentrating on a specific wave-length range: WG-1 - visible and infrared, WG-2 - mid-ultraviolet (200 < A < 300 nm), WG-3 - Far-ultraviolet (lambda greater than 100 and lambda less than 200 nanometers), WG-4 - extreme-ultraviolet (lambda greater than 10 and lambda less than 100 nm), and WG-5 - X-ray (lambda greater than 1 and lambda less than 10 nano meters). The overarching goals of SOLERS22 are to: 1) establish daily solar irradiance values in the specified wavelength ranges, 2) consider the evolving solar structures as the cause of temporal variations, and 3) understand the underlying physical processes driving these changes.

  4. Extreme Ultraviolet Explorer. Long look at the next window

    NASA Technical Reports Server (NTRS)

    Maran, Stephen P.

    1991-01-01

    The Extreme Ultraviolet Explorer (EUVE) will map the entire sky to determine the existence, direction, brightness, and temperature of thousands of objects that are sources of so-called extreme ultraviolet (EUV) radiation. The EUV spectral region is located between the x-ray and ultraviolet regions of the electromagnetic spectrum. From the sky survey by EUVE, astronomers will determine the nature of sources of EUV light in our galaxy, and infer the distribution of interstellar gas for hundreds of light years around the solar system. It is from this gas and the accompanying dust in space that new stars and solar systems are born and to which evolving and dying stars return much of their material in an endless cosmic cycle of birth, death, and rebirth. Besides surveying the sky, astronomers will make detailed studies of selected objects with EUVE to determine their physical properties and chemical compositions. Also, they will learn about the conditions that prevail and the processes at work in stars, planets, and other sources of EUV radiation, maybe even quasars. The EUVE mission and instruments are described. The objects that EUVE will likely find are described.

  5. Cyanobacteria as efficient producers of mycosporine-like amino acids.

    PubMed

    Jain, Shikha; Prajapat, Ganshyam; Abrar, Mustari; Ledwani, Lalita; Singh, Anoop; Agrawal, Akhil

    2017-09-01

    Mycosporine-like amino acids are the most common group of transparent ultraviolet radiation absorbing intracellular secondary metabolites. These molecules absorb light in the range of ultraviolet-A and -B with a maximum absorbance between 310 and 362 nm. Cyanobacteria might have faced the most deleterious ultraviolet radiation, which leads to an evolution of ultraviolet protecting mycosporine-like amino acids for efficient selection in the environment. In the last 30 years, scientists have investigated various cyanobacteria for novel mycosporine-like amino acids, applying different induction techniques. This review organizes all the cyanobacterial groups that produce various mycosporine-like amino acids. We found out that cyanobacteria belonging to orders Synechococcales, Chroococcales, Oscillatoriales, and Nostocales are frequently studied for the presence of mycosporine-like amino acids, while orders Gloeobacterales, Spirulinales, Pleurocapsales, and Chroococcidiopsidales are still need to be investigated. Nostoc and Anabaena strains are major studied genus for the mycosporine-like amino acids production. Hence, this review will give further insight to the readers about potential mycosporine-like amino acid producing cyanobacterial groups in future investigations. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gordon, I.M.; Pichakhchi, L.D.

    It is shown that the emission spectrum of T Tauri stars with anomalous continuous radiation in the ultraviolet can be explained by assuming that it is a negative absorption spectrum of hydrogen excited by synchrotron radiation of great intensity in a small part of the star's atmosphere--in its active zone. A method was also proposed for the determination of the spectrum of synchrotron radiation from the observed hydrogen emission spectrum. The intensity in the infrared part of the spectrum was determined from the broadening of the higher terms of the Balmer series that form the quasicontinuum, while the intensity inmore » the ultraviolet was determined from hydrogen ionization. In the present study the distribution of hydrogen atoms among the excited levels in the field of such radiation is calculated using an electronic computer. The calculations show that the Balmer lines will in fact be observed in emission due to induced transitions, i.e., as a sequence of negative absorption lines. The considerable overpopulation of the upper levels is responsible for the small Balmer decrement and the appearance of anomalous emission in the ultraviolet and also for the increase in intensity of the latter when approaching the Balmer discontinuity. Thus the theory of the excitation of the emission spectrum of T Tauri stars is confirmed quantitatively. (auth)« less

  7. Solar ultraviolet radiation and its impact on aquatic systems of Patagonia, South America.

    PubMed

    Villafañe, V E; Helbling, E W; Zagarese, H E

    2001-03-01

    Solar ultraviolet radiation (UVR, 280-400 nm) is known to cause a number of detrimental effects in aquatic organisms. The area of Patagonia, which is sometimes under the influence of the Antarctic ozone "hole", occasionally receives enhanced levels of ultraviolet B radiation (UV-B, 280-315 nm). Great efforts have been put into creating a database for UVR climatology by installing a variety of instruments in several localities in the region. However, no comparable effort has been made to determine the impact of normal and enhanced levels of solar UVR upon organisms. Most of the photobiological research in aquatic systems of Patagonia has focused on determining the effects of solar UVR in phytoplankton photosynthesis, DNA damage, and mortality, fecundity and repair mechanisms in zooplanktonic species. Some work has also been done with fish larvae and interactions between species at low trophic levels of the aquatic food web. The results of these studies indicate that in order to assess the overall impact of UVR in a certain waterbody, it is also necessary to consider other variables, such as changes in cloudiness, ozone concentrations, differential sensitivity of organisms, and depth of the upper mixed layer/epilimnion. All factors that can preclude or benefit the acclimation of species to solar radiation.

  8. The Spartan-281 Far Ultraviolet Imaging Spectrograph

    NASA Technical Reports Server (NTRS)

    Carruthers, George R.; Heckathorn, Harry M.; Dufour, Reginald J.; Opal, Chet B.; Raymond, John C.

    1988-01-01

    The U.S. Naval Research Laboratory's Far Ultraviolet Imaging Spectrograph (FUVIS), currently under development for flight as a Spartan shuttle payload, is designed to perform spectroscopy of diffuse sources in the FUV with very high sensitivity and moderate spatial and spectral resolution. Diffuse nebulae, the general galactic background radiation, and artificially induced radiation associated with the Space Shuttle vehicle are sources of particular interest. The FUVIS instrument will cover the wavelength range of 970-2000 A with selectable resolutions of 5 and 30 A. It is a slit imaging spectrograph having 3 arcmin spatial resolution along its 2.7 deg long slit.

  9. Environmental phototoxicity: Solar ultraviolet radiation affects the toxicity of natural and man-made chemicals

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Larson, R.A.; Berenbaum, M.R.

    1988-04-01

    Ultraviolet radiation appears to be toxic to all forms of unpigmented living cells, including bacteria, protozoa, nematodes, arthropods, fish, birds, and mammals. In addition to the direct absorption of solar energy by cellular constituents, toxicity may occur because of the absorption of sunlight by xenobiotics (or by naturally occurring compounds outside the target cell); these may be converted by light or by subsequent light-promoted reactions that induce cellular damage. This article describes the phototoxicity of photodynamic dyes, light-activated synthetic herbicides, petroleum and its constituents, and naturally occurring chemicals from plants. Detoxification mechanisms are also discussed.

  10. Near-infrared resonance-mediated chirp control of a coherently generated broadband deep-ultraviolet spectrum

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rybak, Leonid; Chuntonov, Lev; Gandman, Andrey

    2011-09-15

    We investigate the use of shaped near-infrared (NIR) femtosecond pulses to control the generation of coherent broadband deep-ultraviolet (DUV) radiation in an atomic resonance-mediated (2+1) three-photon excitation to a broad far-from-resonance continuum. Previously, we have shown control over the total emitted DUV yield. Here, we experimentally demonstrate phase control over the spectral characteristics (central frequency and bandwidth) of the emitted broadband DUV radiation. It is achieved by tuning the linear chirp applied to the exciting NIR femtosecond pulse. The study is conducted with Na vapor.

  11. Assessing children's ultraviolet radiation exposure: the potential usefulness of a colorimeter.

    PubMed

    Eckhardt, L; Mayer, J A; Creech, L; Johnston, M R; Lui, K J; Sallis, J F; Elder, J P

    1996-12-01

    This study evaluated the colorimeter as an objective measure of children's ultraviolet (UV) radiation exposure. Fifty-eight children, ages 6 to 9 years, attended two summer measurement sessions, with 46 attending a subsequent winter session. Comparisons between summer sessions for the L* scale showed that only the upper arm significantly changed in the tanner direction, while b* scale values indicated significant tanning for all body sites. All exposed body sites changed significantly in the less tan direction between summer and winter measurements. Using colorimeters to objectively measure children's UV exposure has potential applications for skin cancer prevention programs.

  12. Method for determining surface coverage by materials exhibiting different fluorescent properties

    NASA Technical Reports Server (NTRS)

    Chappelle, Emmett W. (Inventor); Daughtry, Craig S. T. (Inventor); Mcmurtrey, James E., III (Inventor)

    1995-01-01

    An improved method for detecting, measuring, and distinguishing crop residue, live vegetation, and mineral soil is presented. By measuring fluorescence in multiple bands, live and dead vegetation are distinguished. The surface of the ground is illuminated with ultraviolet radiation, inducing fluorescence in certain molecules. The emitted fluorescent emission induced by the ultraviolet radiation is measured by means of a fluorescence detector, consisting of a photodetector or video camera and filters. The spectral content of the emitted fluorescent emission is characterized at each point sampled, and the proportion of the sampled area covered by residue or vegetation is calculated.

  13. Effects of atomic oxygen and ultraviolet radiation on candidate elastomeric materials for long duration missions. Test series no.1

    NASA Technical Reports Server (NTRS)

    Linton, R. C.; Finckenor, M. M.; Kamenetzky, R. R.; Gray, P.

    1993-01-01

    Research was conducted at MSFC on the behavior of elastomeric materials after exposure to simulated space environment. Silicone S383 and Viton V747 samples were exposed to thermal vacuum, ultraviolet radiation, and atomic oxygen and then evaluated for changes in material properties. Characterization of the elastomeric materials included weight, hardness, optical inspection under normal and black light, spectrofluorescence, solar absorptance and emittance, Fourier transform infrared spectroscopy, and permeability. These results indicate a degree of sensitivity to exposure and provided some evidence of UV and atomic oxygen synergism.

  14. Ultraviolet and infrared laser-induced fragmentation of free (CF{sub 3}I){sub n} clusters in a molecular beam and (CF{sub 3}I){sub n} clusters inside or on the surface of large (Xe){sub m} clusters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Apatin, V. M.; Lokhman, V. N.; Makarov, G. N., E-mail: gmakarov@isan.troitsk.ru

    The fragmentation of free homogeneous (CF{sub 3}I){sub n} clusters in a molecular beam (n ≤ 45 is the average number of molecules in the cluster) and (CF{sub 3}I){sub n} clusters inside or on the surface of large (Xe){sub m} clusters (m ≥ 100 is the average number of atoms in the cluster) by ultraviolet and infrared laser radiations has been studied. These three types of (CF{sub 3}I){sub n} clusters are shown to have different stabilities with respect to fragmentation by both ultraviolet and infrared radiations and completely different dependences of the fragmentation probability on the energy of ultraviolet and infraredmore » radiations. When exposed to ultraviolet radiation, the free (CF{sub 3}I){sub n} clusters fragment at comparatively low fluences (Φ{sub UV} ≤ 0.15 J cm{sup −2}) and the weakest energy dependence of the fragmentation probability is observed for them. A stronger energy dependence of the fragmentation probability is observed for the (CF{sub 3}I){sub n} clusters localized inside (Xe){sub m} clusters, and the strongest dependence is observed for the (CF{sub 3}I){sub n} clusters located on the surface of (Xe){sub m} clusters. When the clusters are exposed to infrared radiation, the homogeneous (CF{sub 3}I){sub n} clusters efficiently fragment at low fluences (Φ{sub IR} ≤ 25 mJ cm{sup −2}), higher fluences (Φ{sub IR} ≈ 75 mJ cm{sup −2}) are needed for the fragmentation of the (CF{sub 3}I){sub n} localized inside (Xe){sub m} clusters, and even higher fluences (Φ{sub IR} ≈ 150 mJ cm{sup −2}) are needed for the fragmentation of the (CF{sub 3}I){sub n} clusters located on the surface of (Xe){sub m} clusters. It has been established that small (CF{sub 3}I){sub n} clusters located on the surface of (Xe){sub m} clusters do not fragment up to fluences Φ{sub IR} ≈ 250 mJ cm{sup −2}. The fragmentation efficiency of (CF{sub 3}I){sub n} clusters is shown to be the same (at the same fluence) when they are excited by both pulsed (τ{sub p} ≈ 150 ns) and continuous-wave infrared laser radiations. Possible causes of such a pattern of ultraviolet and infrared laser-induced fragmentation of these clusters are discussed.« less

  15. Coal tar phototherapy for psoriasis reevaluated: erythemogenic versus suberythemogenic ultraviolet with a tar extract in oil and crude coal tar

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lowe, N.J.; Wortzman, M.S.; Breeding, J.

    1983-06-01

    Recent studies have questioned the therapeutic value of coal tar versus ultraviolet (UV) radiation and their relative necessity in phototherapy for psoriasis. In this investigation, different aspects of tar phototherapy have been studied in single-blind bilateral paired comparison studies. The effects of 1% crude coal tar were compared with those of petrolatum in conjunction with erythemogenic and suberythemogenic doses of ultraviolet light (UVB) using a FS72 sunlamp tubed cabinet. Crude coal tar was clinically superior to petrolatum with suberythemogenic ultraviolet. With the erythemogenic UVB, petrolatum was equal in efficacy to crude coal tar. Suberythemogenic UVB was also used adjunctively tomore » compare the effects of a 5% concentration of a tar extract in an oil base to 5% crude coal tar in petrolatum or the oil base without tar. The tar extract in oil plus suberythemogenic UVB produced significantly more rapid improvement than the oil base plus UVB. The direct bilateral comparison of equal concentrations of tar extract in oil base versus crude coal tar in petrolatum in a suberythemogenic UV photo regimen revealed no statistical differences between treatments. In a study comparing tar extract in oil and the oil base without ultraviolet radiation, the tar extract in oil side responded more rapidly.« less

  16. Repair of Ultraviolet Radiation Damage in Sensitive Mutants of Micrococcus radiodurans

    PubMed Central

    Moseley, B. E. B.

    1969-01-01

    Various aspects of the repair of ultraviolet (UV) radiation-induced damage were compared in wild-type Micrococcus radiodurans and two UV-sensitive mutants. Unlike the wild type, the mutants are more sensitive to radiation at 265 nm than at 280 nm. The delay in deoxyribonucleic acid (DNA) synthesis following exposure to UV is about seven times as long in the mutants as in the wild type. All three strains excise UV-induced pyrimidine dimers from their DNA, although the rate at which cytosine-thymine dimers are excised is slower in the mutants. The three strains also mend the single-strand breaks that appear in the irradiated DNA as a result of dimer excision, although the process is less efficient in the mutants. It is suggested that the increased sensitivity of the mutants to UV radiation may be caused by a partial defect in the second step of dimer excision. PMID:5773016

  17. THE CYTOLOGY AND GENETICS OF RADIATION RESISTANCE IN BACTERIA. Progress Report for the Period of November 1, 1956 to November 1, 1957

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    1960-10-31

    >The effects of various chemical mutugens on the radiosensitivity of Nocardia corallina were investigated. The application of the unpaired defect theory of Tobias and the ploidy stute in N. corallina were also studied. Nocardia corallina was used as a diploid cell and Micrococcus aureus and Escherichia coli were used as haploid cells for comparative purposes. Chemicals used included nitrogen mustard, sodium azide, copper sulfate, caffeine, ascorbic acid, mercuric chloride, manganous chloride, and hydrogen peroxide. Data are tabulated on the effects of pretreatment with the chemicals on response to ultraviolet and x radiations. Results are also included from a study ofmore » the effects of ultraviolet radiation on the cytology snd colony development of Nocardia corallina. The effects of pigment on radiosensitivity and factors involved in the development of radiation-resistant strains are discussed. (For preceding period see ORO-283.) (C.H.)« less

  18. Integration of a Fire Detector into a Spacecraft

    NASA Technical Reports Server (NTRS)

    Linford, R. M. F.

    1972-01-01

    A detector sensitive to only the ultraviolet radiation emitted by flames has been selected as the basic element of the NASA Skylab fire detection system. It is sensitive to approximately 10(exp -12)W of radiation and will detect small flames at distances in excess of 3m. The performance of the detector was verified by experiments in an aircraft flying zero-gravity parabolas to simulate the characteristics of a fire which the detector must sense. Extensive investigation and exacting design was necessary to exclude all possible sources of false alarms. Optical measurements were made on all the spacecraft windows to determine the amount of solar radiation transmitted. The lighting systems and the onboard experiments also were appraised for ultraviolet emissions. Proton-accelerator tests were performed to determine the interaction of the Earth's trapped radiation belts with the detectors and the design of the instrument was modified to negate these effects.

  19. The Molecular and Physiological Responses of Physcomitrella patens to Ultraviolet-B Radiation1[W][OA

    PubMed Central

    Wolf, Luise; Rizzini, Luca; Stracke, Ralf; Ulm, Roman; Rensing, Stefan A.

    2010-01-01

    Ultraviolet-B (UV-B) radiation present in sunlight is an important trigger of photomorphogenic acclimation and stress responses in sessile land plants. Although numerous moss species grow in unshaded habitats, our understanding of their UV-B responses is very limited. The genome of the model moss Physcomitrella patens, which grows in sun-exposed open areas, encodes signaling and metabolic components that are implicated in the UV-B response in flowering plants. In this study, we describe the response of P. patens to UV-B radiation at the morphological and molecular levels. We find that P. patens is more capable of surviving UV-B stress than Arabidopsis (Arabidopsis thaliana) and describe the differential expression of approximately 400 moss genes in response to UV-B radiation. A comparative analysis of the UV-B response in P. patens and Arabidopsis reveals both distinct and conserved pathways. PMID:20427465

  20. Protective effect of cerium ion against ultraviolet B radiation-induced water stress in soybean seedlings.

    PubMed

    Mao, Chun Xia; Chen, Min Min; Wang, Lei; Zou, Hua; Liang, Chan Juan; Wang, Li Hong; Zhou, Qing

    2012-06-01

    Effects of cerium ion (Ce(III)) on water relations of soybean seedlings (Glycine max L.) under ultraviolet B radiation (UV-B, 280-320 nm) stress were investigated under laboratory conditions. UV-B radiation not only affected the contents of two osmolytes (proline, soluble sugar) in soybean seedlings, but also inhibited the transpiration in soybean seedlings by decreasing the stomatal density and conductance. The two effects caused the inhibition in the osmotic and metabolic absorption of water, which decreased the water content and the free water/bound water ratio. Obviously, UV-B radiation led to water stress, causing the decrease in the photosynthesis in soybean seedlings. The pretreatment with 20 mg L(-1) Ce(III) could alleviate UV-B-induced water stress by regulating the osmotic and metabolic absorption of water in soybean seedlings. The alleviated effect caused the increase in the photosynthesis and the growth of soybean seedlings. It is one of the protective effect mechanisms of Ce(III) against the UV-B radiation-induced damage to plants.

  1. Evaluation of thermal control coatings for use on solar dynamic radiators in low earth orbit

    NASA Technical Reports Server (NTRS)

    Dever, Joyce A.; Rodriguez, Elvin; Slemp, Wayne S.; Stoyack, Joseph E.

    1991-01-01

    Thermal control coatings with high thermal emittance and low solar absorptance are needed for Space Station Freedom (SSF) solar dynamic power module radiator (SDR) surfaces for efficient heat rejection. Additionally, these coatings must be durable to low earth orbital (LEO) environmental effects of atomic oxygen, ultraviolet radiation and deep thermal cycles which occur as a result of start-up and shut-down of the solar dynamic power system. Eleven candidate coatings were characterized for their solar absorptance and emittance before and after exposure to ultraviolet (UV) radiation (200 to 400 nm), vacuum UV (VUV) radiation (100 to 200 nm) and atomic oxygen. Results indicated that the most durable and best performing coatings were white paint thermal control coatings Z-93, zinc oxide pigment in potassium silicate binder, and YB-71, zinc orthotitanate pigment in potassium silicate binder. Optical micrographs of these materials exposed to the individual environmental effects of atomic oxygen and vacuum thermal cycling showed that no surface cracking occurred.

  2. THE EFFECTS OF ULTRAVIOLET LIGHT AND GAMMA RAYS ON CELL LIPIDS AND THE PHYSIOLOGICAL ACTION OF IRRADIATED LIPIDS. Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bernheim, F.; Wilbur, K.M.

    1962-03-26

    Results are summarized from a series of studies on the effects of ultraviolet and ionizing radiation on the oxidation of cell lipids. It was shown that both in vitro and in vivo radiation produced oxidation products of lipids that inhibited the activity of certain oxidative enzymes, depolymerized desoxyribonucleoprotein, inhibited the division of marine eggs, and retarded bacterial growth. The presence of antioxidant activity was also demonstrated in tissues. The significant feature of antioxidant compounds with respect to the biological effects of radiation was shown to be the inhibition of the oxidation of lipids. In irradiated animals the antioxidant activity ofmore » the intestinal mucosa and the activity of phospholipase decreased. Experiments showed that radiation had not destroyed the enzyme but had inactivated the activator. Results are also summarized from a study on the effects of ionizing radiation on cell growth and protein synthesis in yeast. (C.H.)« less

  3. Evaluation of thermal control coatings for use on solar dynamic radiators in low Earth orbit

    NASA Technical Reports Server (NTRS)

    Dever, Joyce A.; Rodriguez, Elvin; Slemp, Wayne S.; Stoyack, Joseph E.

    1991-01-01

    Thermal control coatings with high thermal emittance and low solar absorptance are needed for Space Station Freedom (SSF) solar dynamic power module radiator (SDR) surfaces for efficient heat rejection. Additionally, these coatings must be durable to low earth orbital (LEO) environmental effects of atomic oxygen, ultraviolet radiation and deep thermal cycles which occur as a result of start-up and shut-down of the solar dynamic power system. Eleven candidate coatings were characterized for their solar absorptance and emittance before and after exposure to ultraviolet (UV) radiation (200 to 400 nm), vacuum UV (VUV) radiation (100 to 200 nm) and atomic oxygen. Results indicated that the most durable and best performing coatings were white paint thermal control coatings Z-93, zinc oxide pigment in potassium silicate binder, and YB-71, zinc orthotitanate pigment in potassium silicate binder. Optical micrographs of these materials exposed to the individual environmental effects of atomic oxygen and vacuum thermal cycling showed that no surface cracking occurred.

  4. Comparison of Five Modeling Approaches to Quantify and Estimate the Effect of Clouds on the Radiation Amplification Factor (RAF) for Solar Ultraviolet Radiation

    EPA Science Inventory

    A generally accepted value for the Radiation Amplification Factor (RAF), with respect to the erythemal action spectrum for sunburn of human skin, is −1.1, indicating that a 1.0% increase in stratospheric ozone leads to a 1.1% decrease in the biologically damaging UV radiation in ...

  5. Use of radiation in biomaterials science

    NASA Astrophysics Data System (ADS)

    Benson, Roberto S.

    2002-05-01

    Radiation is widely used in the biomaterials science for surface modification, sterilization and to improve bulk properties. Radiation is also used to design of biochips, and in situ photopolymerizable of bioadhesives. The energy sources most commonly used in the irradiation of biomaterials are high-energy electrons, gamma radiation, ultraviolet (UV) and visible light. Surface modification involves placement of selective chemical moieties on the surface of a material by chemical reactions to improve biointeraction for cell adhesion and proliferation, hemocompatibility and water absorption. The exposure of a polymer to radiation, especially ionizing radiation, can lead to chain scission or crosslinking with changes in bulk and surface properties. Sterilization by irradiation is designed to inactivate most pathogens from the surface of biomedical devices. An overview of the use of gamma and UV radiation to improve surface tissue compatibility, bulk properties and surface properties for wear resistance, formation of hydrogels and curing dental sealants and bone adhesives is presented. Gamma and vacuum ultraviolet (VUV) irradiated ultrahigh molecular weight polyethylene (UHMWPE) exhibit improvement in surface modulus and hardness. The surface modulus and hardness of UHMWPE showed a dependence on type of radiation, dosage and processing. VUV surface modified e-PTFE vascular grafts exhibit increases in hydrophilicity and improvement towards adhesion of fibrin glue.

  6. Occupational skin cancer induced by ultraviolet radiation and its prevention.

    PubMed

    Diepgen, T L; Fartasch, M; Drexler, H; Schmitt, J

    2012-08-01

    Skin cancer is by far the most common kind of cancer diagnosed in many western countries and ultraviolet radiation is the most important risk factor for cutaneous squamous cell carcinoma (SCC) and basal cell carcinoma (BCC). Although employees at several workplaces are exposed to increased levels of UV radiation, skin cancer due to long-term intense occupational exposure to UV radiation is often not considered as occupational disease. The actually available evidence in the epidemiological literature clearly indicates that occupational UV radiation exposure is a substantial and robust risk factor for the development of cutaneous SCC and also clearly shows a significant risk for developing BCC. There is enough scientific evidence that outdoor workers have an increased risk of developing work-related occupational skin cancer due to natural UV radiation exposure and adequate prevention strategies must be implemented. The three measures which are successful and of particular importance in the prevention of nonmelanoma skin cancer in outdoor workers are changes in behaviour regarding awareness of health and disease resulting from exposure to natural UV radiation, protection from direct UV radiation by wearing suitable clothing, and regular and correct use of appropriate sunscreens. © 2012 The Authors. BJD © 2012 British Association of Dermatologists.

  7. Satellite estimation of surface spectral ultraviolet irradiance using OMI data in East Asia

    NASA Astrophysics Data System (ADS)

    Lee, H.; Kim, J.; Jeong, U.

    2017-12-01

    Due to a strong influence to the human health and ecosystem environment, continuous monitoring of the surface ultraviolet (UV) irradiance is important nowadays. The amount of UVA (320-400 nm) and UVB (290-320 nm) radiation at the Earth surface depends on the extent of Rayleigh scattering by atmospheric gas molecules, the radiative absorption by ozone, radiative scattering by clouds, and both absorption and scattering by airborne aerosols. Thus advanced consideration of these factors is the essential part to establish the process of UV irradiance estimation. Also UV index (UVI) is a simple parameter to show the strength of surface UV irradiance, therefore UVI has been widely utilized for the purpose of UV monitoring. In this study, we estimate surface UV irradiance at East Asia using realistic input based on OMI Total Ozone and reflectivity, and then validate this estimated comparing to UV irradiance from World Ozone and Ultraviolet Radiation Data Centre (WOUDC) data. In this work, we also try to develop our own retrieval algorithm for better estimation of surface irradiance. We use the Vector Linearized Discrete Ordinate Radiative Transfer (VLIDORT) model version 2.6 for our UV irradiance calculation. The input to the VLIDORT radiative transfer calculations are the total ozone column (TOMS V7 climatology), the surface albedo (Herman and Celarier, 1997) and the cloud optical depth. Based on these, the UV irradiance is calculated based on look-up table (LUT) approach. To correct absorbing aerosol, UV irradiance algorithm added climatological aerosol information (Arola et al., 2009). The further study, we analyze the comprehensive uncertainty analysis based on LUT and all input parameters.

  8. Resistance of the Extreme Halophile Halobacterium sp. NRC-1 to Multiple Stresses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gygli, Patrick E.; Prajapati, Surendra; DeVeaux, Linda C.

    2009-03-10

    The model Archaeon Halobacterium sp. NRC-1 is an extreme halophile known for its resistance to multiple stressors, including electron-beam and ultraviolet radiation. It is a well-developed system with a completely sequenced genome and extensive post-genomic tools for the study of a variety of biological processes. To further understand the mechanisms of Halobacterium's, radiation resistance, we previously reported the selection for multiple independent highly resistant mutants using repeated exposure to high doses of 18-20 MeV electrons using a medical S-band Linac. Molecular analysis of the transcriptional profile of several of these mutants revealed a single common change: upregulation of the rfa3more » operon. These genes encode proteins homologous to the subunits of eukaryotic Replication Protein A (RPA), a DNA binding protein with major roles in DNA replication, recombination, and repair. This operon has also been implicated in a somewhat lesser role in resistance of wild type Halobacterium to ultraviolet radiation, suggesting common mechanisms for resistance. To further understand the mechanism of radiation resistance in the mutant strains, we measured the survival after exposure to both electron-beam and ultraviolet radiation, UV-A, B, and C All mutant strains showed increased resistance to electrons when compared with the parent. However, the mutant strains do not display increased UV resistance, and in one case is more sensitive than the parent strain. Thus, the protective role of increased RPA expression within a cell may be specific to the DNA damage caused by the different physical effects induced by high energy electron-beam radiation.« less

  9. Conversion of far ultraviolet to visible radiation: absolute measurements of the conversion efficiency of tetraphenyl butadiene

    NASA Astrophysics Data System (ADS)

    Vest, Robert E.; Coplan, Michael A.; Clark, Charles W.

    Far ultraviolet (FUV) scintillation of noble gases is used in dark matter and neutrino research and in neutron detection. Upon collisional excitation, noble gas atoms recombine into excimer molecules that decay by FUV emission. Direct detection of FUV is difficult. Another approach is to convert it to visible light using a wavelength-shifting medium. One such medium, tetraphenyl butadiene (TPB) can be vapor-deposited on substrates. Thus the quality of thin TPB films can be tightly controlled. We have measured the absolute efficiency of FUV-to-visible conversion by 1 μm-thick TPB films vs. FUV wavelengths between 130 and 300 nm, with 1 nm resolution. The energy efficiency of FUV to visible conversion varies between 1% and 5%. We make comparisons with other recent results. Work performed at the NIST SURF III Synchrotron Ultraviolet Radiation Facility,.

  10. Enhancements in biologically effective ultraviolet radiation following volcanic eruptions

    NASA Technical Reports Server (NTRS)

    Vogelmann, A. M.; Ackerman, T. P.; Turco, R. P.

    1992-01-01

    A radiative transfer model is used to estimate the changes in biologically effective radiation (UV-BE) at the earth's surface produced by the El Chichon (1982) and Mount Pinatubo (1991) eruptions. It is found that in both cases surface intensity can increase because the effect of ozone depletion outweighs the increased scattering.

  11. Decontamination Efficacy of Ultraviolet Radiation against Biofilms of Common Nosocomial Bacteria.

    PubMed

    Tingpej, Pholawat; Tiengtip, Rattana; Kondo, Sumalee

    2015-06-01

    Ultraviolet radiation (UV) is commonly used to destroy microorganisms in the health-care environment. However, the efficacy of UV radiation against bacteria growing within biofilms has never been studied. To measure the sterilization effectiveness of UV radiation against common healthcare associated pathogens growing within biofilms. Staphylococcus aureus, Methicillin-resistant S. aureus (MRSA), Streptococcus epidermidis, Escherichia coli, ESBL-producing E. coli, Pseudomonas aeruginosa and Acinetobacter baumannii were cultivated in the Calgary Biofilm Device. Their biofilms were placed 50 cm from the UV lamp within the Biosafety Cabinet. Viability test, crystal violet assay and a scanning electron microscope were used to evaluate the germicidal efficacy. Within 5 minutes, UV radiation could kill S. aureus, MRSA, S. epidermidis, A. baumannii and ESBL-producing E. coli completely while it required 20 minutes and 30 minutes respectively to kill E. coli and P. aeruginosa. However, the amounts of biomass and the ultrastructure between UV-exposed biofilms and controls were not significantly different. UV radiation is effective in inactivating nosocomial pathogens grown within biofilms, but not removing biofilms and EPS. The biofilm of P. aeruginosa was the most durable.

  12. SR-71 Ship #1 - Ultraviolet Experiment

    NASA Technical Reports Server (NTRS)

    1994-01-01

    NASA's SR-71 streaks into the twilight on a night/science flight from the Dryden Flight Research Center, Edwards, California. Mounted in the nose of the SR-71 was an ultraviolet video camera aimed skyward to capture images of stars, asteroids and comets. The science portion of the flight is a project of the Jet Propulsion Laboratory, Pasadena, California. Two SR-71 aircraft have been used by NASA as test beds for high-speed and high-altitude aeronautical research. One early research project flown on one of Dryden's SR-71s consisted of a proposal for a series of flights using the SR-71 as a science camera platform for the Jet Propulsion Laboratory (JPL) of the California Institute of Technology, which operates under contract to NASA in much the way that NASA centers do. In March 1993, an upward-looking ultraviolet (UV) video camera placed in the SR-71's nosebay studied a variety of celestial objects in the ultraviolet light spectrum. The SR-71 was proposed as a test bed for the experiment because it is capable of flying at altitudes above 80,000 feet for an extended length of time. Observation of ultraviolet radiation is not possible from the Earth's surface because the atmosphere's ozone layer absorbs UV rays. Study of UV radiation is important because it is known to cause skin cancer with prolonged exposure. UV radiation is also valuable to study from an astronomical perspective. Satellite study of ultraviolet radiation is very expensive. As a result, the South West Research Institute (SWRI) in Texas developed the hypothesis of using a high-flying aircraft such as the SR-71 to conduct UV observations. The SR-71 is capable of flying above 90 percent of the Earth's atmosphere. The flight program was also designed to test the stability of the aircraft as a test bed for UV observation. A joint flight program was developed between the JPL and NASA's Ames-Dryden Flight Research Facility (redesignated the Dryden Flight Research Center, Edwards, California, in 1994) in conjunction with SWRI to test the hypothesis. Dryden modified the nosebay of the SR-71, creating an upward-observing window to carry SWRI's ultraviolet CCD camera so it could make observations. According to Dryden's SR-71 Project Manager Dave Lux, a single flight of the aircraft confirmed the aircraft's capability and stability as a test bed for UV observations. SWRI's principle investigator was Dr. Allen Stern.

  13. CHARACTERIZATION OF RELATIVE SENSITIVITY OF AMPHIBIANS TO ULTRA VIOLET RADIATION

    EPA Science Inventory

    Different studies have demonstrated that solar ultraviolet (UV) radiation can adversely affect survival and development of embryonic and larval amphibians. However, because of among-laboratory variations in exposure profiles (artificial vs. natural sunlight; natural sunlight at d...

  14. PHOTOACTIVATED TOXICITY IN AQUATIC ENVIRONMENTS

    EPA Science Inventory

    Most aquatic organisms have evolved mechanisms to minimize damage by ultraviolet (UV) radiation. Many terrestrial species have additionally had to adapt to plant compounds (e.g. furanocoumarins) that are extremely toxic when activated by UV radiation. Over evolutionary time, it i...

  15. Evidence that Singlet Oxygen-induced Human T Helper Cell Apoptosis Is the Basic Mechanism of Ultraviolet-A Radiation Phototherapy

    PubMed Central

    Morita, Akimichi; Werfel, Thomas; Stege, Helger; Ahrens, Constanze; Karmann, Karin; Grewe, Markus; Grether-Beck, Susanne; Ruzicka, Thomas; Kapp, Alexander; Klotz, Lars-Oliver; Sies, Helmut; Krutmann, Jean

    1997-01-01

    Ultraviolet A (UVA) irradiation is effectively used to treat patients with atopic dermatitis and other T cell mediated, inflammatory skin diseases. In the present study, successful phototherapy of atopic dermatitis was found to result from UVA radiation-induced apoptosis in skin-infiltrating T helper cells, leading to T cell depletion from eczematous skin. In vitro, UVA radiation-induced human T helper cell apoptosis was mediated through the FAS/FAS-ligand system, which was activated in irradiated T cells as a consequence of singlet oxygen generation. These studies demonstrate that singlet oxygen is a potent trigger for the induction of human T cell apoptosis. They also identify singlet oxygen generation as a fundamental mechanism of action operative in phototherapy. PMID:9362536

  16. The Photodissociation of HCN and HNC: Effects on the HNC/HCN Abundance Ratio in the Interstellar Medium

    NASA Astrophysics Data System (ADS)

    Aguado, Alfredo; Roncero, Octavio; Zanchet, Alexandre; Agúndez, Marcelino; Cernicharo, José

    2017-03-01

    The impact of the photodissociation of HCN and HNC isomers is analyzed in different astrophysical environments. For this purpose, the individual photodissociation cross sections of HCN and HNC isomers have been calculated in the 7-13.6 eV photon energy range for a temperature of 10 K. These calculations are based on the ab initio calculation of three-dimensional adiabatic potential energy surfaces of the 21 lower electronic states. The cross sections are then obtained using a quantum wave packet calculation of the rotational transitions needed to simulate a rotational temperature of 10 K. The cross section calculated for HCN shows significant differences with respect to the experimental one, and this is attributed to the need to consider non-adiabatic transitions. Ratios between the photodissociation rates of HCN and HNC under different ultraviolet radiation fields have been computed by renormalizing the rates to the experimental value. It is found that HNC is photodissociated faster than HCN by a factor of 2.2 for the local interstellar radiation field and 9.2 for the solar radiation field, at 1 au. We conclude that to properly describe the HNC/HCN abundance ratio in astronomical environments illuminated by an intense ultraviolet radiation field, it is necessary to use different photodissociation rates for each of the two isomers, which are obtained by integrating the product of the photodissociation cross sections and ultraviolet radiation field over the relevant wavelength range.

  17. Method and apparatus for passive optical dosimeter comprising caged dye molecules

    DOEpatents

    Sandison, David R.

    2001-07-03

    A new class of ultraviolet dosimeters is made possible by exposing caged dye molecules, which generate a dye molecule on exposure to ultraviolet radiation, to an exterior environment. Applications include sunburn monitors, characterizing the UV exposure history of UV-sensitive materials, especially including structural plastics, and use in disposable `one-use` optical equipment, especially medical devices.

  18. Stabilized unsaturated polyesters

    NASA Technical Reports Server (NTRS)

    Vogl, O.; Borsig, E. (Inventor)

    1985-01-01

    An unsaturated polyester, such as propylene glycolmaleic acid phthalic acid prepolymer dissolved in styrene is interpolymerized with an ultraviolet absorber and/or an antioxidant. The unsaturated chain may be filled with H or lower alkyl such as methyl and tertiary alkyl such as tertiary butyl. A polymer stable to exposure to the outdoors without degradation by ultraviolet radiation, thermal and/or photooxidation is formed.

  19. Modelling and Display of the Ultraviolet Sky

    NASA Astrophysics Data System (ADS)

    Daniels, J.; Henry, R.; Murthy, J.; Allen, M.; McGlynn, T. A.; Scollick, K.

    1994-12-01

    A computer program is currently under development to model in 3D - one dimension of which is wavelength - all the known and major speculated sources of ultraviolet (900 A - 3100 A ) radiation over the celestial sphere. The software is being written in Fortran 77 and IDL and currently operates under IRIX (the operating system of the Silicon Graphics Iris Machine); all output models are in FITS format. Models along with display software will become available to the astronomical community. The Ultraviolet Sky Model currently includes the Zodiacal Light, Point Sources of Emission, and the Diffuse Galactic Light. The Ultraviolet Sky Model is currently displayed using SkyView: a package under development at NASA/ GSFC, which allows users to retrieve and display publically available all-sky astronomical survey data (covering many wavebands) over the Internet. We present a demonstration of the SkyView display of the Ultraviolet Model. The modelling is a five year development project: the work illustrated here represents product output at the end of year one. Future work includes enhancements to the current models and incorporation of the following models: Galactic Molecular Hydrogen Fluorescence; Galactic Highly Ionized Atomic Line Emission; Integrated Extragalactic Light; and speculated sources in the intergalactic medium such as Ionized Plasma and radiation from Non-Baryonic Particle Decay. We also present a poster which summarizes the components of the Ultraviolet Sky Model and outlines a further package that will be used to display the Ultraviolet Model. This work is supported by United States Air Force Contract F19628-93-K-0004. Dr J. Daniels is supported with a post-doctoral Fellowship from the Leverhulme Foundation, London, United Kingdom. We are also grateful for the encouragement of Dr Stephen Price (Phillips Laboratory, Hanscomb Air Force Base, MA)

  20. Glacial Influences on Solar Radiation in a Subarctic Sea.

    EPA Science Inventory

    Understanding macroscale processes controlling solar radia­tion in marine systems will be important in interpreting the potential effects of global change from increasing ultraviolet radiation (UV) and glacial retreat. This study provides the first quantitative assessment of UV i...

  1. Prediction of Coral Bleaching in the Florida Keys Using Remotely Sensed Data

    EPA Science Inventory

    Coral bleaching has been attributed to extremes or stressful synergy in several physical variables of the coral habitat. Of particular concern have been temperature, ultraviolet radiation, and photosynthetically available radiation. Satellite observing systems allow synoptic-sca...

  2. Cell damage caused by ultraviolet B radiation in the desert cyanobacterium Phormidium tenue and its recovery process.

    PubMed

    Wang, Gaohong; Deng, Songqiang; Liu, Jiafeng; Ye, Chaoran; Zhou, Xiangjun; Chen, Lanzhou

    2017-10-01

    Phormidium tenue, a cyanobacterium that grows in the topsoil of biological soil crusts (BSCs), has the highest recovery rate among desert crust cyanobacteria after exposure to ultraviolet B (UV-B) radiation. However, the mechanism underlying its recovery process is unclear. To address this issue, we measured chlorophyll a fluorescence, generation of reactive oxygen species (ROS), lipid peroxidation, and repair of DNA breakage in P. tenue following exposure to UV-B. We found that UV-B radiation at all doses tested reduced photosynthesis and induced cell damage in P. tenue. However, P. tenue responded to UV-B radiation by rapidly reducing photosynthetic activity, which protects the cell by leaking less ROS. Antioxidant enzymes, DNA damage repair systems, and UV absorbing pigments were then induced to mitigate the damage caused by UV-B radiation. The addition of exogenous antioxidant chemicals ascorbate and N-acetylcysteine also mitigated the harmful effects caused by UV-B radiation and enhanced the recovery process. These chemicals could aid in the resistance of P. tenue to the exposure of intense UV-B radiation in desertified areas when inoculated onto the sand surface to form artificial algal crusts. Copyright © 2017. Published by Elsevier Inc.

  3. Protective effect of rare earth against oxidative stress under ultraviolet-B radiation.

    PubMed

    Wang, Lihong; Huang, Xiaohua; Zhou, Qing

    2009-04-01

    The effects of lanthanum (III) (La(III)) in protecting soybean leaves against oxidative stress induced by ultraviolet-B (UV-B) radiation were investigated. The increase in contents of hydrogen peroxide (H(2)O(2)) and superoxide (O2*-) due to UV-B radiation suggested oxidative stress. The increase in the content of malondialdehyde (MDA) and the decrease in the index of unsaturated fatty acid (IUFA) indicated oxidative damage on cell membrane induced by UV-B radiation. La(III) partially reversed UV-B-radiation-induced damage of plant growth. The reduction in the contents of H(2)O(2), O2*-, and MDA and increase in the content of IUFA, compared with UV-B treatment, also indicated that La(III) alleviated the oxidative damage induced by UV-B radiation. The increase in the activities of superoxide dismutase and peroxidase and the contents of ascorbate, carotenoids, and flavonoids were observed in soybean leaves with La(III) + UV-B treatment, compared with UV-B treatment. Our data suggested that La(III) could protect soybean plants from UV-B-radiation-induced oxidative stress by reacting with reactive oxygen species directly or by improving the defense system of plants.

  4. Investigation of the effect of atmospheric dust on the determination of total ozone from the earth's ultraviolet reflectivity measurements

    NASA Technical Reports Server (NTRS)

    Dave, J. V.

    1977-01-01

    Results are presented on the effect of atmospheric aerosols on the value of total ozone, in an atmospheric column of the terrestrial atmosphere, estimated from the simulated measurements of the ultraviolet radiation back scattered by the earth atmosphere models. Simulated measurements were used in five (configuration of the BUV experiment of Nimbus-4 satellite), and in six (configuration of the TOMS section of the SBUV/TOMS experiment on Nimbus-G) narrow spectral regions in the ultraviolet part of the spectrum.

  5. Space Radiation Detector with Spherical Geometry

    NASA Technical Reports Server (NTRS)

    Wrbanek, John D. (Inventor); Fralick, Gustave C. (Inventor); Wrbanek, Susan Y. (Inventor)

    2011-01-01

    A particle detector is provided, the particle detector including a spherical Cherenkov detector, and at least one pair of detector stacks. In an embodiment of the invention, the Cherenkov detector includes a sphere of ultraviolet transparent material, coated by an ultraviolet reflecting material that has at least one open port. The Cherenkov detector further includes at least one photodetector configured to detect ultraviolet light emitted from a particle within the sphere. In an embodiment of the invention, each detector stack includes one or more detectors configured to detect a particle traversing the sphere.

  6. Space Radiation Detector with Spherical Geometry

    NASA Technical Reports Server (NTRS)

    Wrbanek, John D. (Inventor); Fralick, Gustave C. (Inventor); Wrbanek, Susan Y. (Inventor)

    2012-01-01

    A particle detector is provided, the particle detector including a spherical Cherenkov detector, and at least one pair of detector stacks. In an embodiment of the invention, the Cherenkov detector includes a sphere of ultraviolet transparent material, coated by an ultraviolet reflecting material that has at least one open port. The Cherenkov detector further includes at least one photodetector configured to detect ultraviolet light emitted from a particle within the sphere. In an embodiment of the invention, each detector stack includes one or more detectors configured to detect a particle traversing the sphere.

  7. The Extreme Ultraviolet Explorer

    NASA Technical Reports Server (NTRS)

    Malina, R. F.; Bowyer, S.; Lampton, M.; Finley, D.; Paresce, F.; Penegor, G.; Heetderks, H.

    1982-01-01

    The Extreme Ultraviolet Explorer Mission is described. The purpose of this mission is to search the celestial sphere for astronomical sources of extreme ultraviolet (EUV) radiation (100 to 1000 A). The search will be accomplished with the use of three EUV telescopes, each sensitive to different bands within the EUV band. A fourth telescope will perform a higher sensitivity search of a limited sample of the sky in a single EUV band. In six months, the entire sky will be scanned at a sensitivity level comparable to existing surveys in other more traditional astronomical bandpasses.

  8. Calculating Solar Ultraviolet Irradiation Of The Human Cornea And Corresponding Required Sunglass Lens Transmittances

    NASA Astrophysics Data System (ADS)

    Hoover, Herbert L.; Marsaud, Serge G.

    1986-05-01

    Tinted ophthalmic lenses are used primarily for eye comfort in a brightly lit environment. An ancillary benefit is the attenuation of ultraviolet radiation. Some national product standards specify quantitative limits for ultraviolet transmittances. Such limits ought to be founded on quantitative estimates of solar irradiances of ocular tissues, with actinic effectiveness taken into account. We use the equations of Green and coworkers for direct and diffuse solar irradiance at the earth's surface to calculate average sky and ground spectral radiances. We use the geometric factors derived by us for the coupling of radiation from these sources to the human cornea. Actinically weighted corneal spectral irradiances integrated over wavelength and time yield peak irradiances and accumulated exposure doses that are compared with recommended exposure limits. This provides the maximal effective ultraviolet transmittances of tinted ophthalmic lenses such that these exposure limits will not be exceeded in the selected exposure environment. The influences on corneal irradiation of such exposure parameters as solar zenith angle, altitude of the exposure site, characteristics of atmospheric aerosols, and ground reflectances are illustrated. The relationships between the effective transmittance (which is a function of the environmental radiation and any actinicweighting function) and readily determined characteristics of the lens itself, viz., its mean transmittance, and a selected spectral transmittance, are derived for three lens transmittance curves. Limits of lens transmittance for the UV-B and UV-A wavelength regions are presented for several representative exposure sites in Europe and the U.S.A.

  9. Lifetimes and f-values of the D 2Σ- ← X 2Π system of OH and OD

    NASA Astrophysics Data System (ADS)

    Heays, Alan; de Oliveira, Nelson; Gans, Bérenger; Ito, Kenji; Boyé-Péronne, Séverine; Douin, Stéphane; Hickson, Kevin; Nahon, Laurent; Loison, Jean-Christophe

    2017-10-01

    The OH radical is abundant in the interstellar medium and cometary comae, where it plays a significant role in the photochemical cycle of water. Also, the oxidising potential of the Earth atmosphere is influenced by this molecule. The OH lifetime in the presence of ultraviolet radiation is of prime interest in all these locations. The vacuum-ultraviolet absorption of the D 2Σ- ← X 2Π system contributes to a reduction of this lifetime. It also provides an independent way to observe the OH molecule in the interstellar medium. But a reliable oscillator strength (f-value) is needed. Vacuum-ultraviolet absorption of the D 2Σ- ← X 2Π system of OH and OD was recorded with high spectral resolution in a plasma-discharge radical source and using synchrotron radiation coupled to the unique ultraviolet Fourier-transform spectrometer on the DESIRS beamline of synchrotron SOLEIL. Line oscillator strengths are absolutely calibrated with respect to the well-known A 2Σ+ ← X 2Π system. The new oscillator strength decreases the best-estimate lifetime of OH in an interstellar radiation field and reduces its uncertainty. We also measured line broadening of the excited D 2Σ- v=0 and 1 levels for the first time and find a lifetime for these states which is 5 times shorter than theoretically predicted.This new data will aid in the interpretation of astronomical observations and help improve photochemical models in many contexts.

  10. Development of Ultraviolet (UV) Radiation Protective Fabric Using Combined Electrospinning and Electrospraying Technique

    NASA Astrophysics Data System (ADS)

    Sinha, Mukesh Kumar; Das, B. R.; Kumar, Kamal; Kishore, Brij; Prasad, N. Eswara

    2017-06-01

    The article reports a novel technique for functionization of nanoweb to develop ultraviolet (UV) radiation protective fabric. UV radiation protection effect is produced by combination of electrospinning and electrospraying technique. A nanofibrous web of polyvinylidene difluoride (PVDF) coated on polypropylene nonwoven fabric is produced by latest nanospider technology. Subsequently, web is functionalized by titanium dioxide (TiO2). The developed web is characterized for evaluation of surface morphology and other functional properties; mechanical, chemical, crystalline and thermal. An optimal (judicious) nanofibre spinning condition is achieved and established. The produced web is uniformly coated by defect free functional nanofibres in a continuous form of useable textile structural membrane for ultraviolet (UV) protective clothing. This research initiative succeeds in preparation and optimization of various nanowebs for UV protection. Field Emission Scanning Electron Microscope (FESEM) result reveals that PVDF webs photo-degradative behavior is non-accelerated, as compared to normal polymeric grade fibres. Functionalization with TiO2 has enhanced the photo-stability of webs. The ultraviolet protection factor of functionalized and non-functionalized nanowebs empirically evaluated to be 65 and 24 respectively. The developed coated layer could be exploited for developing various defence, para-military and civilian UV protective light weight clothing (tent, covers and shelter segments, combat suit, snow bound camouflaging nets). This research therefore, is conducted in an attempt to develop a scientific understanding of PVDF fibre coated webs for photo-degradation and applications for defence protective textiles. This technological research in laboratory scale could be translated into bulk productionization.

  11. Assessing children's ultraviolet radiation exposure: the potential usefulness of a colorimeter.

    PubMed Central

    Eckhardt, L; Mayer, J A; Creech, L; Johnston, M R; Lui, K J; Sallis, J F; Elder, J P

    1996-01-01

    OBJECTIVES: This study evaluated the colorimeter as an objective measure of children's ultraviolet (UV) radiation exposure. METHODS: Fifty-eight children, ages 6 to 9 years, attended two summer measurement sessions, with 46 attending a subsequent winter session. RESULTS: Comparisons between summer sessions for the L* scale showed that only the upper arm significantly changed in the tanner direction, while b* scale values indicated significant tanning for all body sites. All exposed body sites changed significantly in the less tan direction between summer and winter measurements. CONCLUSIONS: Using colorimeters to objectively measure children's UV exposure has potential applications for skin cancer prevention programs. PMID:9003142

  12. Vacuum Ultraviolet Radiation Desorption of Molecular Contaminants Deposited on Quartz Crystal Microbalances

    NASA Technical Reports Server (NTRS)

    Albyn, Keith; Burns, Dewitt

    2006-01-01

    Recent quartz crystal microbalance measurements made in the Marshall Space Flight Center, Photo-Deposition Facility, for several materials, recorded a significant loss of deposited contaminants when the deposition surface of the microbalance was illuminated by a deuterium lamp. These measurements differ from observations made by other investigators in which the rate of deposition increased significantly when the deposition surface was illuminated with vacuum ultraviolet radiation. These observations suggest that the accelerated deposition of molecular contaminants on optically sensitive surfaces is dependant upon the contaminant being deposited and must be addressed during the materials selection process by common material screening techniques.

  13. Generation of vacuum ultraviolet radiation by intracavity high-harmonic generation toward state detection of single trapped ions

    NASA Astrophysics Data System (ADS)

    Wakui, Kentaro; Hayasaka, Kazuhiro; Ido, Tetsuya

    2014-12-01

    Vacuum ultraviolet (VUV) radiation around 159 nm is obtained toward direct excitation of a single trapped ion. An efficient fluoride-based VUV output coupler is employed for intracavity high-harmonic generation of a Ti:S oscillator. Using this coupler, where we measured its reflectance to be about 90 %, an average power reaching 6.4 W is coupled out from a modest fundamental power of 650 mW. When a single comb component out of 1.9 10 teeth is resonant to the atomic transition, 100s of fluorescence photons per second will be detectable under a realistic condition.

  14. Laser-produced lithium plasma as a narrow-band extended ultraviolet radiation source for photoelectron spectroscopy.

    PubMed

    Schriever, G; Mager, S; Naweed, A; Engel, A; Bergmann, K; Lebert, R

    1998-03-01

    Extended ultraviolet (EUV) emission characteristics of a laser-produced lithium plasma are determined with regard to the requirements of x-ray photoelectron spectroscopy. The main features of interest are spectral distribution, photon flux, bandwidth, source size, and emission duration. Laser-produced lithium plasmas are characterized as emitters of intense narrow-band EUV radiation. It can be estimated that the lithium Lyman-alpha line emission in combination with an ellipsoidal silicon/molybdenum multilayer mirror is a suitable EUV source for an x-ray photoelectron spectroscopy microscope with a 50-meV energy resolution and a 10-mum lateral resolution.

  15. KSC-97PC1032

    NASA Image and Video Library

    1997-07-10

    A payload canister in the Payload Changeout Room (PCR) at Launch Pad 39A holds the Cryogenic Infrared Spectrometers and Telescopes for the Atmosphere-Shuttle Pallet Satellite-2 (CRISTA-SPAS-2) payload for the STS-85 mission (center), as well as the Technology Applications and Science-1 (TAS-1) (top) and International Extreme Ultraviolet Hitchhiker-2 (IEH-2) (bottom) payloads. All three will be transferred from the PCR into the payload bay of the Space Shuttle Orbiter Discovery after the space vehicle arrives at the pad. The CRISTA is a system of three telescopes and four spectrometers to measure infrared radiation emitted by the Earth’s middle atmosphere. During the 11-day mission, the CRISTA-SPAS-2 free-flying satellite will be deployed from Discovery and retrieved later in the flight. Also onboard the satellite will be the Middle Atmosphere High Resolution Spectrograph Investigation (MAHRSI) to measure ultraviolet radiation emitted and scattered by the Earth’s atmosphere. The TAS-1 holds seven separate experiments that will provide data on the Earth’s topography and atmosphere, study the sun’s energy, and test new thermal control devices, as well as several student-developed experiments. The IEH-2 experiments will study ultraviolet radiation from stars, the sun and in the solar system

  16. KSC-97PC1008

    NASA Image and Video Library

    1997-07-07

    The Technology Applications and Science-1 (TAS-1) payload for the STS-85 mission rests in a payload canister in the Space Station Processing Facility prior to its trip out to Launch Pad 39A for installation into the payload bay of the Space Shuttle Orbiter Discovery. The TAS-1 holds seven separate experiments that will provide data on the Earth’s topography and atmosphere, study the sun’s energy, and test new thermal control devices, as well as several student-developed experiments. Other STS-85 payloads include the Cryogenic Infrared Spectrometers and Telescopes for the Atmosphere-Shuttle Pallet Satellite-2 (CRISTA-SPAS-2). The CRISTA is a system of three telescopes and four spectrometers to measure infrared radiation emitted by the Earth’s middle atmosphere. During the 11-day mission, the CRISTA-SPAS-2 free-flying satellite will be deployed from Discovery and retrieved later in the flight. Also onboard the satellite will be the Middle Atmosphere High Resolution Spectrograph Investigation (MAHRSI) to measure ultraviolet radiation emitted and scattered by the Earth’s atmosphere. The International Extreme Ultraviolet Hitchhiker-2 (IEH-2) will also be in the payload bay. The IEH-2 experiments will study ultraviolet radiation from stars, the sun and in the solar system

  17. KSC-97PC1033

    NASA Image and Video Library

    1997-07-10

    A payload canister in the Payload Changeout Room (PCR) at Launch Pad 39A holds the Cryogenic Infrared Spectrometers and Telescopes for the Atmosphere-Shuttle Pallet Satellite-2 (CRISTA-SPAS-2) payload for the STS-85 mission (center), as well as the Technology Applications and Science-1 (TAS-1) (top) and International Extreme Ultraviolet Hitchhiker-2 (IEH-2) (bottom) payloads. All three will be transferred from the PCR into the payload bay of the Space Shuttle Orbiter Discovery after the space vehicle arrives at the pad. The CRISTA is a system of three telescopes and four spectrometers to measure infrared radiation emitted by the Earth’s middle atmosphere. During the 11-day mission, the CRISTA-SPAS-2 free-flying satellite will be deployed from Discovery and retrieved later in the flight. Also onboard the satellite will be the Middle Atmosphere High Resolution Spectrograph Investigation (MAHRSI) to measure ultraviolet radiation emitted and scattered by the Earth’s atmosphere. The TAS-1 holds seven separate experiments that will provide data on the Earth’s topography and atmosphere, study the sun’s energy, and test new thermal control devices, as well as several student-developed experiments. The IEH-2 experiments will study ultraviolet radiation from stars, the sun and in the solar system

  18. ULTRAVIOLET RADIATION IN NORTH AMERICAN LAKES: ATTENUATION ESTIMATES FROM DOC MEASUREMENTS AND IMPLICATIONS FOR PLANKTON COMMUNITIES

    EPA Science Inventory

    Climate warming in North America is likely to be accompanied by changes in other environmental stresses such as UV-B radiation. We apply an empirical model to available DOC (dissolved organic C) data to estimate the depths to which 1% of surface UV-B and UV-A radiation penetrate ...

  19. UPDATE ON COORDINATED STUDIES OF AMPHIBIAN DISTRIBUTIONS AND UV RADIATION

    EPA Science Inventory

    In February of 2000 researchers from the EPA, the National Park Service, other governmental agencies, and academia formulated a plan for coordinated studies of amphibian distributions and aquatic ultraviolet radiation exposure risks in several national parks. At this point we hav...

  20. POTENTIAL IMPACTS OF INCREASED SOLAR UV-B ON GLOBAL PLANT PRODUCTIVITY

    EPA Science Inventory

    Ultraviolet-B radiation comprises only a small portion of the electromagnetic spectrum but has a disproportionately large photobiological effect. oth plants and animals are greatly affected by increases in UV-B radiation but there exists tremendous variability in the sensitivity ...

  1. The New Cosmos

    ERIC Educational Resources Information Center

    McCray, Richard A.

    1970-01-01

    Discusses areas of modern astronomy that owe their development largely to nonoptical radiation: radio, infrared, ultraviolet, and x-ray radiation. Indicates new observations favor the big-bang" model of the universe, for it is now established that the earth is expanding at a measurable rate. Annotated bibliography. (LS)

  2. Synthesis of vitamin D and erythemal irradiance obtained with a multiband filter radiometer and annual variation analysis in Río Gallegos, Argentina

    NASA Astrophysics Data System (ADS)

    Orte, P. F.; Wolfram, E. A.; Salvador, J.; D'Elia, R.; Paes Leme, N.; Quel, E. J.

    2011-01-01

    In this paper we examined the annual variability of the erythemal solar radiation (a health risk) and the solar irradiance for synthesis of vitamin D (a health benefit) in Río Gallegos, Argentina. We use ultraviolet radiation measurements made by a multiband filter radiometer GUV-541 and a Brewer spectrophotometer located at CEILAP-RG Station (CITEFA-CONICET) (51° 33' S, 69° 19' W). These measurements are weighted with action spectra published by the CIE (International Commission on Illumination). An action spectrum describes the relative effectiveness of different wavelengths in the generation of a particular biological response. The analyzed data correspond to September 2008-December 2009 period. The methodology used to obtain the erythemal irradiance and synthesis of vitamin D values combines irradiance measurements of a multiband filter radiometer with modeled values (output of radiative transfer model) and measurements of a Brewer spectrophotometer. This procedure increases the instrumental capabilities of this instrument. The synthesis of vitamin D and erythema are affected by UVB solar radiation. Therefore, its effect is strongly dependent of the stratospheric ozone amount, which undergoes large variations in the Río Gallegos city due to ozone hole passage and its influence on these sub-polar latitudes. We observed that could exist cases of sunburn for reasonable exposure in abnormal situations of low total ozone column, resulting in high levels of ultraviolet radiation. Furthermore, the synthesis of vitamin D through exposure to ultraviolet radiation would be lower than the appropriate values to the majority of the year for these latitudes. Therefore it is important to evaluate the annual variation of these quantities realizing seasonal balance between this health risk and this health benefit.

  3. [Climatic changes in Scandinavia--consequences for public health].

    PubMed

    Kanestrøm, I

    1999-01-30

    Atmospheric composition and climate conditions are of great importance for health. Increasing consumption of fossil fuels ever since the industrial revolution has resulted in higher contents of greenhouse gases in the atmosphere. Primarily, this will increase the global temperature. Secondarily, it may change the patterns of precipitation and droughts. Higher extreme temperatures will have a negative effect on health. Climate changes can also change the living conditions of undesirable insects and microbes. The ozone gas in the atmosphere acts as a shield against the harmful ultraviolet radiation from the sun. Chlorofluorocarbons contribute to reduction of the ozone layer and increase ultraviolet radiation. Increased exposure of the skin to this radiation may cause damage such as sunburn and skin cancer. In order to avoid damage, it is of importance to wear protective clothing or use effective sunshades.

  4. Influence of ambient ultraviolet radiation on Bufo calamita egg development in a semiarid zone (Catalonia, Spain).

    PubMed

    Oromi, Neus; Marquis, Olivier; Miaud, Claude; Sanuy, Delfi

    2008-01-01

    Several experiments have shown that ambient ultraviolet-B radiation (UV-B) has negative effects on the development of amphibians' embryos. We studied the effects of UV-B radiation on development, survival and frequency of deformity during egg development in the Natterjack toad (Bufo calamita) from a semiarid region of Lleida (Catalonia, Spain). Eggs exposed to ambient levels of UV-B and those protected from UV-B with a filter exhibited similar developmental rate, mortality rate and frequency of developmental anomalies. These experiments show that eggs of Bufo calamita of the studied population are able to develop normally during embryonic period when exposed to current high levels of UV-B observed in Catalonia. These results will be used as reference for future studies on geographic variation in UV-B tolerance in this species.

  5. Low Earth orbital atomic oxygen and ultraviolet radiation effects on polymers

    NASA Technical Reports Server (NTRS)

    Dever, Joyce A.

    1991-01-01

    Because atomic oxygen and solar ultraviolet radiation present in the low earth orbital (LEO) environment can alter the chemistry of polymers resulting in degradation, their effects and mechanisms of degradation must be determined in order to determine the long term durability of polymeric surfaces to be exposed on missions such as Space Station Freedom. The effects of atomic oxygen on polymers which contain protective coatings must also be explored, since unique damage mechanisms can occur in areas where the protective coatings has failed. Mechanisms can be determined by utilizing results from previous LEO missions, by performing ground based LEO simulation tests and analysis, and by carrying out focussed space experiments. A survey is presented of the interactions and possible damage mechanisms for environmental atomic oxygen and UV radiation exposure of polymers commonly used in LEO.

  6. IRIS Ultraviolet Spectral Properties of a Sample of X-Class Solar Flares

    NASA Astrophysics Data System (ADS)

    Butler, Elizabeth; Kowalski, Adam; Cauzzi, Gianna; Allred, Joel C.; Daw, Adrian N.

    2018-06-01

    The white-light (near-ultraviolet (NUV) and optical) continuum emission comprises the majority of the radiated energy in solar flares. However, there are nearly as many explanations for the origin of the white-light continuum radiation as there are white-light flares that have been studied in detail with spectra. Furthermore, there are rarely robust constraints on the time-resolved dynamics in the white-light emitting flare layers. We are conducting a statistical study of the properties of Fe II lines, Mg II lines, and NUV continuum intensity in bright flare kernels observed by the Interface Region Imaging Spectrograph (IRIS), in order to provide comprehensive constraints for radiative-hydrodynamic flare models. Here we present a new technique for identifying bright flare kernels and preliminary relationships among IRIS spectral properties for a sample of X-class solar flares.

  7. Cured composite materials for reactive metal battery electrolytes

    DOEpatents

    Harrup, Mason K.; Stewart, Frederick F.; Peterson, Eric S.

    2006-03-07

    A solid molecular composite polymer-based electrolyte is made for batteries, wherein silicate compositing produces a electrolytic polymer with a semi-rigid silicate condensate framework, and then mechanical-stabilization by radiation of the outer surface of the composited material is done to form a durable and non-tacky texture on the electrolyte. The preferred ultraviolet radiation produces this desirable outer surface by creating a thin, shallow skin of crosslinked polymer on the composite material. Preferably, a short-duration of low-medium range ultraviolet radiation is used to crosslink the polymers only a short distance into the polymer, so that the properties of the bulk of the polymer and the bulk of the molecular composite material remain unchanged, but the tough and stable skin formed on the outer surface lends durability and processability to the entire composite material product.

  8. Ultraviolet Radiation Round-Robin Testing of Various Backsheets for Photovoltaic Modules

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Koehl, Michael; Ballion, Amal; Lee, Yu-Hsien

    2015-06-14

    Durability testing of materials exposed to natural weathering requires testing of the ultraviolet (UV) stability, especially for polymeric materials. The type approval testing of photovoltaic (PV) modules according to standards IEC 61215 and IEC 61646, which includes a so-called UV preconditioning test with a total UV dose of 15 kWh/m2, does not correspond to the real loads during lifetime. Between 3%-10% of the UV radiation has to be in the spectral range between 280 and 320 nm (UV-B) in the recent editions of the standards. However, the spectral distribution of the radiation source is very important because different samples showmore » very individual spectral sensitivity for the radiation offered. Less than 6% of the intensity of solar radiation exists in the UV range. In the case of an increase of the intensity of the light source for accelerating the UV test, overheating of the samples would have to be prevented more rigorously and the temperature of the samples have to be measured to avoid misinterpretation of the test results.« less

  9. Interactions between the impacts of ultraviolet radiation, elevated CO2, and nutrient limitation on marine primary producers.

    PubMed

    Beardall, John; Sobrino, Cristina; Stojkovic, Slobodanka

    2009-09-01

    It is well known that UV radiation can cause deleterious effects to the physiological performance, growth and species assemblages of marine primary producers. In this review we describe the range of interactions observed between these impacts of ultraviolet radiation (UVR, 280-400 nm) with other environmental factors such as the availability of photosynthetically active radiation (PAR), nutrient status and levels of dissolved CO2, all of which can, in turn, be influenced by global climate change. Thus, increases in CO2 levels can affect the sensitivity of some species to UV-B radiation (UV-B), while others show no such impact on UV-B susceptibility. Both nitrogen- and phosphorus-limitation can have direct interactive effects on the susceptibility of algal cells and communities to UVR, though such effects are somewhat variable. Nutrient depletion can also potentially lead to a dominance of smaller celled species, which may be less able to screen out and are thus likely to be more susceptible to UVR-induced damage. The variability of responses to such interactions can lead to alterations in the species composition of algal assemblages.

  10. Effects of ultraviolet radiation and contaminant-related stressors on arctic freshwater ecosystems.

    PubMed

    Wrona, Frederick J; Prowse, Terry D; Reist, James D; Hobbie, John E; Lévesque, Lucie M J; Macdonald, Robie W; Vincent, Warwick F

    2006-11-01

    Climate change is likely to act as a multiple stressor, leading to cumulative and/or synergistic impacts on aquatic systems. Projected increases in temperature and corresponding alterations in precipitation regimes will enhance contaminant influxes to aquatic systems, and independently increase the susceptibility of aquatic organisms to contaminant exposure and effects. The consequences for the biota will in most cases be additive (cumulative) and multiplicative (synergistic). The overall result will be higher contaminant loads and biomagnification in aquatic ecosystems. Changes in stratospheric ozone and corresponding ultraviolet radiation regimes are also expected to produce cumulative and/or synergistic effects on aquatic ecosystem structure and function. Reduced ice cover is likely to have a much greater effect on underwater UV radiation exposure than the projected levels of stratospheric ozone depletion. A major increase in UV radiation levels will cause enhanced damage to organisms (biomolecular, cellular, and physiological damage, and alterations in species composition). Allocations of energy and resources by aquatic biota to UV radiation protection will increase, probably decreasing trophic-level productivity. Elemental fluxes will increase via photochemical pathways.

  11. Optical Properties of Thermal Control Coatings After Weathering, Simulated Ascent Heating, and Simulated Space Radiation Exposure

    NASA Technical Reports Server (NTRS)

    Jaworske, Donald A.; Tuan, George C.; Westheimer, David T.; Peters, Wanda C.; Kauder, Lonny R.

    2008-01-01

    Spacecraft radiators reject heat to their surroundings and coatings play an important role in this heat rejection. The coatings provide the combined optical properties of low solar absorptance and high infrared emittance. The coatings are applied to the radiator panel in a number of ways, including conventional spraying, plasma spraying, or as an applique. Not designed for a terrestrial weathering environment, the durability of spacecraft paints, coatings, and appliques upon exposure to weathering and subsequent exposure to ascent heating, solar wind, and ultraviolet radiation was studied. In addition to traditional aluminum panels, new isocyanate ester composite panels were exposed for a total of 90 days at the Atmospheric Exposure Site of Kennedy Space Center's (KSC) Beach Corrosion Facility for the purpose of identifying their durability to weathering. Selected panel coupons were subsequently exposed to simulated ascent heating, solar wind, and vacuum ultraviolet (UV) radiation to identify the effect of a simulated space environment on as-weathered surfaces. Optical properties and adhesion testing were used to document the durability of the paints, coatings, and appliques.

  12. Effects of elevated ultraviolet radiation on primary metabolites in selected alpine algae and cyanobacteria

    PubMed Central

    Hartmann, Anja; Albert, Andreas; Ganzera, Markus

    2015-01-01

    Extremophilic green algae and cyanobacteria are the most abundant species in high mountain habitats, where rough climate conditions such as temperature differences, limited water retention and high ultraviolet (UV) radiation are the cause for a restricted biological diversity in favor of a few specialized autotrophic microorganisms. In this study, we investigated four algal species from alpine habitat in a sun simulator for their defense strategies in response to UV-A radiation (315–400 nm) up to 13.4 W/m2 and UV-B radiation (280–315 nm) up to 2.8 W/m2. Besides changes in pigment composition we discovered that primary polar metabolites like aromatic amino acids, nucleic bases and nucleosides are increasingly produced when the organisms are exposed to elevated UV radiation. Respective compounds were isolated and identified, and in order to quantify them an HPLC-DAD method was developed and validated. Our results show that especially tyrosine and guanosine were found to be generally two to three times upregulated in the UV-B exposed samples compared to the non-treated control. PMID:26065817

  13. Increased resistance to ionizing and ultraviolet radiation in Escherichia coli JM83 is associated with a chromosomal rearrangement.

    PubMed

    McLean, K M; Gutman, P D; Minton, K W; Clark, E P

    1992-06-01

    Cells cope with radiation damage through several mechanisms: (1) increased DNA repair activity, (2) scavenging and inactivation of radiation-induced radical molecules, and (3) entry into a G0-like quiescent state. We have investigated a chromosomal rearrangement to elucidate further the molecular and genetic mechanisms underlying these phenomena. A mutant of Escherichia coli JM83 (phi 80dlacZ delta M15) was isolated that demonstrated significantly increased resistance to both ionizing and ultraviolet radiation. Surviving fractions of mutant and wild-type cells were measured following exposure to standardized doses of radiation. Increased radioresistance was directly related to a chromosomal alteration near the bacteriophage phi 80 attachment site (attB), as initially detected by the LacZ- phenotype of the isolate. Southern hybridization of chromosomal DNA from the mutant and wild-type E. coli JM83 strains indicated that a deletion had occurred. We propose that the deletion near the attB locus produces the radioresistant phenotype of the E. coli JM83 LacZ- mutant, perhaps through the alteration or inactivation of a gene or its controlling element(s).

  14. SEURAT: SPH scheme extended with ultraviolet line radiative transfer

    NASA Astrophysics Data System (ADS)

    Abe, Makito; Suzuki, Hiroyuki; Hasegawa, Kenji; Semelin, Benoit; Yajima, Hidenobu; Umemura, Masayuki

    2018-05-01

    We present a novel Lyman alpha (Ly α) radiative transfer code, SEURAT (SPH scheme Extended with Ultraviolet line RAdiative Transfer), where line scatterings are solved adaptively with the resolution of the smoothed particle hydrodynamics (SPH). The radiative transfer method implemented in SEURAT is based on a Monte Carlo algorithm in which the scattering and absorption by dust are also incorporated. We perform standard test calculations to verify the validity of the code; (i) emergent spectra from a static uniform sphere, (ii) emergent spectra from an expanding uniform sphere, and (iii) escape fraction from a dusty slab. Thereby, we demonstrate that our code solves the {Ly} α radiative transfer with sufficient accuracy. We emphasize that SEURAT can treat the transfer of {Ly} α photons even in highly complex systems that have significantly inhomogeneous density fields. The high adaptivity of SEURAT is desirable to solve the propagation of {Ly} α photons in the interstellar medium of young star-forming galaxies like {Ly} α emitters (LAEs). Thus, SEURAT provides a powerful tool to model the emergent spectra of {Ly} α emission, which can be compared to the observations of LAEs.

  15. ESTIMATION OF UV RADIATION DOSE IN NORTHERN MINNESOTA WETLANDS

    EPA Science Inventory

    The ultraviolet (UV) B wavelength range (280 nm to 320 nm) of solar radiation can be a significant biological stressor, and has been hypothesized to be partially responsible for amphibian declines and malformation. This hypothesis has been difficult to evaluate, in part, because ...

  16. X-ray lasers. Citations from the International Aerospace Abstracts data base

    NASA Technical Reports Server (NTRS)

    Mauk, S. C.

    1980-01-01

    Various aspects of X-ray lasers are discussed in approximately 122 citations. Included are laser plasmas and outputs, plasma radiation, far ultraviolet radiation, gamma rays, optical pumping, optical resonators, and electron transitions. Laser applications, laser materials, and laser fusion are also included.

  17. 40 CFR 58.1 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... humidity, solar radiation, ultraviolet radiation, and/or precipitation. Metropolitan Statistical Area (MSA... receiver at opposite ends of the monitoring path; (2) Equal to twice the monitoring path length for a (monostatic) system having a transmitter and receiver at one end of the monitoring path and a mirror or...

  18. 40 CFR 58.1 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... humidity, solar radiation, ultraviolet radiation, and/or precipitation. Metropolitan Statistical Area (MSA... receiver at opposite ends of the monitoring path; (2) Equal to twice the monitoring path length for a (monostatic) system having a transmitter and receiver at one end of the monitoring path and a mirror or...

  19. 40 CFR 58.1 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... humidity, solar radiation, ultraviolet radiation, and/or precipitation. Metropolitan Statistical Area (MSA... receiver at opposite ends of the monitoring path; (2) Equal to twice the monitoring path length for a (monostatic) system having a transmitter and receiver at one end of the monitoring path and a mirror or...

  20. RISK ASSESSMENT FOR THE EFFECTS OF SOLAR RADIATION ON AMPHIBIANS

    EPA Science Inventory

    Recent studies have demonstrated that exposure to solar ultraviolet radiation (UVR) can cause mortality and increase the occurrence of eye and limb malformation in some species of amphibians. Based on these reports and various field observations, it has been hypothesized that UV...

  1. Radiation and Plasma Environments for Lunar Missions

    NASA Technical Reports Server (NTRS)

    Minow, Joseph I.; Edwards, David L.; Altstatt, Richard L.; Diekmann, Anne M.; Blackwell, William C., Jr.; Harine, Katherine J.

    2006-01-01

    Space system design for lunar orbit and extended operations on the lunar surface requires analysis of potential system vulnerabilities to plasma and radiation environments to minimize anomalies and assure that environmental failures do not occur during the mission. Individual environments include the trapped particles in Earth s radiation belts, solar energetic particles and galactic cosmic rays, plasma environments encountered in transit to the moon and on the lunar surface (solar wind, terrestrial magnetosheath and magnetotail, and lunar photoelectrons), and solar ultraviolet and extreme ultraviolet photons. These are the plasma and radiation environments which contribute to a variety of effects on space systems including total ionizing dose and dose rate effects in electronics, degradation of materials in the space environment, and charging of spacecraft and lunar dust. This paper provides a survey of the relevant charged particle and photon environments of importance to lunar mission design ranging from the lowest (approx.few 10 s eV) photoelectron energies to the highest (approx.GeV) cosmic ray energies.

  2. Solar ultraviolet radiation cataract.

    PubMed

    Löfgren, Stefan

    2017-03-01

    Despite being a treatable disease, cataract is still the leading cause for blindness in the world. Solar ultraviolet radiation is epidemiologically linked to cataract development, while animal and in vitro studies prove a causal relationship. However, the pathogenetic pathways for the disease are not fully understood and there is still no perfect model for human age related cataract. This non-comprehensive overview focus on recent developments regarding effects of solar UV radiation wavebands on the lens. A smaller number of fundamental papers are also included to provide a backdrop for the overview. Future studies are expected to further clarify the cellular and subcellular mechanisms for UV radiation-induced cataract and especially the isolated or combined temporal and spatial effects of UVA and UVB in the pathogenesis of human cataract. Regardless of the cause for cataract, there is a need for advances in pharmaceutical or other treatment modalities that do not require surgical replacement of the lens. Copyright © 2016. Published by Elsevier Ltd.

  3. Extreme ultraviolet spectroscopy diagnostics of low-temperature plasmas based on a sliced multilayer grating and glass capillary optics.

    PubMed

    Kantsyrev, V L; Safronova, A S; Williamson, K M; Wilcox, P; Ouart, N D; Yilmaz, M F; Struve, K W; Voronov, D L; Feshchenko, R M; Artyukov, I A; Vinogradov, A V

    2008-10-01

    New extreme ultraviolet (EUV) spectroscopic diagnostics of relatively low-temperature plasmas based on the application of an EUV spectrometer and fast EUV diodes combined with glass capillary optics is described. An advanced high resolution dispersive element sliced multilayer grating was used in the compact EUV spectrometer. For monitoring of the time history of radiation, filtered fast EUV diodes were used in the same spectral region (>13 nm) as the EUV spectrometer. The radiation from the plasma was captured by using a single inexpensive glass capillary that was transported onto the spectrometer entrance slit and EUV diode. The use of glass capillary optics allowed placement of the spectrometer and diodes behind the thick radiation shield outside the direction of a possible hard x-ray radiation beam and debris from the plasma source. The results of the testing and application of this diagnostic for a compact laser plasma source are presented. Examples of modeling with parameters of plasmas are discussed.

  4. UNLAMINATED GAFCHROMIC EBT3 FILM FOR ULTRAVIOLET RADIATION MONITORING.

    PubMed

    Welch, David; Randers-Pehrson, Gerhard; Spotnitz, Henry M; Brenner, David J

    2017-11-01

    Measurement of ultraviolet (UV) radiation is important for human health, especially with the expanded usage of short wavelength UV for sterilization purposes. This work examines unlaminated Gafchromic EBT3 film for UV radiation monitoring. The authors exposed the film to select wavelengths in the UV spectrum, ranging from 207 to 328 nm, and measured the change in optical density. The response of the film is wavelength dependent, and of the wavelengths tested, the film was most sensitive to 254 nm light, with measurable values as low as 10 µJ/cm2. The film shows a dose-dependent response that extends over more than four orders of magnitude. The response of the film to short wavelength UV is comparable to the daily safe exposure limits for humans, thus making it valuable as a tool for passive UV radiation monitoring. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  5. Long-term survival of bacterial spores in space

    NASA Technical Reports Server (NTRS)

    Horneck, G.; Bucker, H.; Reitz, G.

    1994-01-01

    On board of the NASA Long Duration Exposure Facility (LDEF), spores of Bacillus subtilis in monolayers (10(exp 6)/sample) or multilayers (10(exp 8)/sample) were exposed to the space environment for nearly six years and their survival was analyzed after retrieval. The response to space parameters, such as vacuum (10(exp -6) Pa), solar electromagnetic radiation up to the highly energetic vacuum-ultraviolet range 10(exp 9) J/sq m) and/or cosmic radiation (4.8 Gy), was studied and compared to the results of a simultaneously running ground control experiment. If shielded against solar ultraviolet (UV)-radiation, up to 80% of spores in multilayers survive in space. Solar UV-radiation, being the most deleterious parameter of space, reduces survival by 4 orders of magnitude or more. However, up to 10(exp 4) viable spores were still recovered, even in completely unprotected samples. Substances, such as glucose or buffer salts serve as chemical protectants. With this 6 year study in space, experimental data are provided to the discussion on the likelihood of 'Panspermia'.

  6. Simulated Space Vacuum Ultraviolet (VUV) Exposure Testing for Polymer Films

    NASA Technical Reports Server (NTRS)

    Dever, Joyce A.; Pietromica, Anthony J.; Stueber, Thomas J.; Sechkar, Edward A.; Messer, Russell K.

    2002-01-01

    Vacuum ultraviolet (VUV) radiation of wavelengths between 115 and 200 nm produced by the sun in the space environment can cause degradation to polymer films producing changes in optical, mechanical, and chemical properties. These effects are particularly important for thin polymer films being considered for ultra-lightweight space structures, because, for most polymers, VUV radiation is absorbed in a thin surface layer. NASA Glenn Research Center has developed facilities and methods for long-term ground testing of polymer films to evaluate space environmental VUV radiation effects. VUV exposure can also be used as part of sequential simulated space environmental exposures to determine combined damaging effects. This paper will describe the effects of VUV on polymer films and the necessity for ground testing. Testing practices used at Glenn Research Center for VUV exposure testing will be described including characterization of the VUV radiation source used, calibration procedures traceable to the National Institute of Standards and Technology (NIST), and testing techniques for VUV exposure of polymer surfaces.

  7. Effects of ultraviolet-B radiation on fungal disease development in Cucumis sativus

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Orth, A.B.; Teramura, A.H.; Sisler, H.D.

    1990-09-01

    Stratospheric ozone depletion due to increased atmospheric pollutants has received considerable attention because of the potential increase in ultraviolet-B (UV-B, 280-320 nm) radiation that will reach the earth's surface. Three cucumber (Cucumis sativus L.) cultivars were exposed to a daily dose of 11.6 kJ m{sup {minus}2} biologically effective ultraviolet-B (UV-B{sub BE}) radiation in an unshaded greenhouse before and/or after injection by Colletotrichum lagenarium (Pass.) Ell. and Halst. or Cladosporium cucumerinum Ell. and Arth. and analyzed for disease development. Two of these cultivars, Poinsette and Calypso Hybrid, were disease resistant, while the third cultivar, Straight-8, was disease susceptible. Preinfectional treatment ofmore » 1 to 7 days with UV-B{sub BE} in Straight-8 led to greater severity of both diseases. Postinfectional UV treatment did not lead to increased disease severity caused by C. lagenarium, while preinfectional UV treatment in both Straight-8 and Poinsette substantially increased disease severity. Although resistant cultivars Poinsette and Calypso Hybrid showed increased anthracnose disease severity when exposed to UV-B, this effect was apparent only on the cotyledons. Both higher spore concentration and exposure to UV-B radiation resulted in greater disease severity. Of the cucumber cultivars tested for UV-B sensitivity, growth in Poinsette was most sensitive and Calypso Hybrid was least sensitive. These preliminary results indicate that the effects of UV-B radiation on disease development in cucumber vary depending on cultivar, timing and duration of UV-B exposure, inoculation level, and plant age.« less

  8. Improved Statistical Model Of 10.7-cm Solar Radiation

    NASA Technical Reports Server (NTRS)

    Vedder, John D.; Tabor, Jill L.

    1993-01-01

    Improved mathematical model simulates short-term fluctuations of flux of 10.7-cm-wavelength solar radiation during 91-day averaging period. Called "F10.7 flux", important as measure of solar activity and because it is highly correlated with ultraviolet radiation causing fluctuations in heating and density of upper atmosphere. F10.7 flux easily measureable at surface of Earth.

  9. On the backscatter of solar He II, 304 A radiation from interplanetary He/+/.

    NASA Technical Reports Server (NTRS)

    Paresce, F.; Bowyer, S.

    1973-01-01

    Backscatter of solar He II, 304 A radiation by interplanetary positive helium ions is shown to be insufficient to account for recent observations of this airglow radiation in the night sky at rocket altitudes. In fact, for most viewing directions, the expected intensities probably fall well below the sensitivity threshold of existing extreme ultraviolet instrumentation.

  10. Growth, bioconversion of isoflavones and probiotic properties of parent and subsequent passages of Lactobacillus upon ultraviolet radiation.

    PubMed

    Yeo, Siok-Koon; Liong, Min-Tze

    2012-11-01

    The objective of this study was to evaluate the effects of ultraviolet (UV) radiation (UVB; 90 J/m²) on growth, bioconversion of isoflavones and probiotic properties of parent and subsequent passages of L. casei FTDC 2113. UV radiation significantly enhanced (P < 0.05) the growth of parent cells in mannitol-soymilk fermented at 37°C for 24 h. This had led to an enhanced intracellular and extracellular β-glucosidase activity with a subsequent increase in bioconversion of isoflavones in mannitol-soymilk (P < 0.05). UV radiation also promoted (P < 0.05) the tolerance of parent cells towards acidic condition (pH 2 and 3) and intestinal bile salts (oxgall, taurocholic and cholic acid). In addition, parent treated cells also exhibited better (P < 0.05) adhesion ability to mucin and antimicrobial activity compared to that of the control. All these positive effects of UV radiation were only prevalent in the parent cells without inheritance by first, second and third passage of cells. Although temporary, our results suggested that UV radiation could enhance the bioactive and probiotic potentials of L. casei FTDC 2113, and thus could be applied for the production of probiotic products with enhanced bioactivity.

  11. Ultraweak photon emission induced by visible light and ultraviolet A radiation via photoactivated skin chromophores: in vivo charge coupled device imaging.

    PubMed

    Prasad, Ankush; Pospíšil, Pavel

    2012-08-01

    Solar radiation that reaches Earth's surface can have severe negative consequences for organisms. Both visible light and ultraviolet A (UVA) radiation are known to initiate the formation of reactive oxygen species (ROS) in human skin by photosensitization reactions (types I and II). In the present study, we investigated the role of visible light and UVA radiation in the generation of ROS on the dorsal and the palmar side of a hand. The ROS are known to oxidize biomolecules such as lipids, proteins, and nucleic acids to form electronically excited species, finally leading to ultraweak photon emission. We have employed a highly sensitive charge coupled device camera and a low-noise photomultiplier tube for detection of two-dimensional and one-dimensional ultraweak photon emission, respectively. Our experimental results show that oxidative stress is generated by the exposure of human skin to visible light and UVA radiation. The oxidative stress generated by UVA radiation is claimed to be significantly higher than that by visible light. Two-dimensional photon imaging can serve as a potential tool for monitoring the oxidative stress in the human skin induced by various stress factors irrespective of its physical or chemical nature.

  12. Ultraviolet-induced responses in two species of climax tropical marine macrophytes.

    PubMed

    Detrés, Y; Armstrong, R A; Connelly, X M

    2001-09-01

    In tropical regions nominal reductions in stratospheric ozone could be detrimental to marine organisms that live near their upper tolerance levels of ultraviolet (UV) radiation and temperature. Well-known plant responses to UV include inhibition of photosynthesis, reductions in chlorophyll content, morphological changes and production of UV absorbing compounds such as flavonoids. An assessment of the effects and responses of two tropical marine macrophytes to full solar radiation and solar radiation depleted of UV were conducted in southwestern Puerto Rico. Changes in concentration of photosynthetic and photoprotective pigments, and in leaf optical properties of the red mangrove Rhizophora mangle and the seagrass Thalassia testudinum, were evaluated in field exclusion experiments. Rhizophora mangle exposed to full solar radiation showed lower leaf reflectance and a shift of 5 nm in the inflection point of the red edge. Thalassia testudinum samples excluded from UV had significant increases in total chlorophyll and carotenoid concentrations. These marine macrophytes showed increments in their concentration of UV-B absorbing compounds with exposure to UV radiation. Results indicate that even minor increases in UV radiation at low latitudes could have significant effects on the pigment composition of these climax species.

  13. Effect of ultraviolet light on mood, depressive disorders and well-being.

    PubMed

    Veleva, Bistra I; van Bezooijen, Rutger L; Chel, Victor G M; Numans, Mattijs E; Caljouw, Monique A A

    2018-06-01

    Human and animal studies have shown that exposure to ultraviolet light can incite a chain of endocrine, immunologic, and neurohumoral reactions that might affect mood. This review focuses on the evidence from clinical trials and observational studies on the effect of ultraviolet light on mood, depressive disorders, and well-being. A search was made in PubMed, Embase, Web of Science, Cochrane, Psychinfo, CINAHL, Academic Search Premier and Science Direct, and the references of key papers, for clinical trials and observational studies describing the effect of ultraviolet light applied to skin or eyes on mood, depressive disorders, and well-being. Of the seven studies eligible for this review, the effect of ultraviolet light on mood, depressive symptoms and seasonal affective disorders was positive in six of them. Of the seven studies, six demonstrated benefit of exposure to ultraviolet radiation and improvement in mood which supports a positive effect of ultraviolet light on mood. Because of the small number of the studies and their heterogeneity, more research is warranted to confirm and document this correlation. © 2018 The Authors. Photodermatology, Photoimmunology & Photomedicine Published by John Wiley & Sons Ltd.

  14. Astro-1 Image Taken by the Ultraviolet Imaging Telescope

    NASA Technical Reports Server (NTRS)

    1990-01-01

    This is a presentation of two comparison images of the Spiral Galaxy M81 in the constellation URA Major. The galaxy is about 12-million light years from Earth. The left image is the Spiral Galaxy M81 as photographed by the Ultraviolet Imaging Telescope (UIT) during the Astro-1 Mission (STS-35) on December 9, 1990. This UIT photograph, made with ultraviolet light, reveals regions where new stars are forming at a rapid rate. The right image is a photograph of the same galaxy in red light made with a 36-inch (0.9-meter) telescope at the Kitt Peak National Observatory near Tucson, Arizona. The Astro Observatory was designed to explore the universe by observing and measuring ultraviolet radiation from celestial objects. Three instruments made up the Astro Observatory: The Hopkins Ultraviolet Telescope (HUT), the Ultraviolet Imaging Telescope (UIT), and the Wisconsin Ultraviolet Photo-Polarimetry Experiment (WUPPE). The Marshall Space Flight Center had management responsibilities for the Astro-1 mission. The Astro-1 Observatory was launched aboard the Space Shuttle Orbiter Columbia (STS-35) on December 2, 1990.

  15. Spacelab

    NASA Image and Video Library

    1990-12-09

    This is a presentation of two comparison images of the Spiral Galaxy M81 in the constellation URA Major. The galaxy is about 12-million light years from Earth. The left image is the Spiral Galaxy M81 as photographed by the Ultraviolet Imaging Telescope (UIT) during the Astro-1 Mission (STS-35) on December 9, 1990. This UIT photograph, made with ultraviolet light, reveals regions where new stars are forming at a rapid rate. The right image is a photograph of the same galaxy in red light made with a 36-inch (0.9-meter) telescope at the Kitt Peak National Observatory near Tucson, Arizona. The Astro Observatory was designed to explore the universe by observing and measuring ultraviolet radiation from celestial objects. Three instruments made up the Astro Observatory: The Hopkins Ultraviolet Telescope (HUT), the Ultraviolet Imaging Telescope (UIT), and the Wisconsin Ultraviolet Photo-Polarimetry Experiment (WUPPE). The Marshall Space Flight Center had management responsibilities for the Astro-1 mission. The Astro-1 Observatory was launched aboard the Space Shuttle Orbiter Columbia (STS-35) on December 2, 1990.

  16. Biological countermeasures in space radiation health.

    PubMed

    Kennedy, Ann R; Todd, Paul

    2003-06-01

    Exposure to the types of ionizing radiation encountered during space travel may cause a number of health-related problems, but the primary concern is related to the increased risk of cancer induction in astronauts. The major types of radiation considered to be of importance during space travel are protons and particles of high atomic number and high energy (HZE particles). It is now clear that biological countermeasures can be used to prevent or reduce the levels of biological consequences resulting from exposure to protons or HZE particles, including the induction of cancer, immunosuppression and neurological defects caused by these types of ionizing radiation. Research related to the dietary additions of agents to minimize the risks of developing health-related problems which can result from exposure to space radiations is reviewed.

  17. Biological countermeasures in space radiation health

    NASA Technical Reports Server (NTRS)

    Kennedy, Ann R.; Todd, Paul

    2003-01-01

    Exposure to the types of ionizing radiation encountered during space travel may cause a number of health-related problems, but the primary concern is related to the increased risk of cancer induction in astronauts. The major types of radiation considered to be of importance during space travel are protons and particles of high atomic number and high energy (HZE particles). It is now clear that biological countermeasures can be used to prevent or reduce the levels of biological consequences resulting from exposure to protons or HZE particles, including the induction of cancer, immunosuppression and neurological defects caused by these types of ionizing radiation. Research related to the dietary additions of agents to minimize the risks of developing health-related problems which can result from exposure to space radiations is reviewed.

  18. Therapeutic radiation and the potential risk of second malignancies.

    PubMed

    Kamran, Sophia C; Berrington de Gonzalez, Amy; Ng, Andrea; Haas-Kogan, Daphne; Viswanathan, Akila N

    2016-06-15

    Radiation has long been associated with carcinogenesis. Nevertheless, it is an important part of multimodality therapy for many malignancies. It is critical to assess the risk of secondary malignant neoplasms (SMNs) after radiation treatment. The authors reviewed the literature with a focus on radiation and associated SMNs for primary hematologic, breast, gynecologic, and pediatric tumors. Radiation appeared to increase the risk of SMN in all of these; however, this risk was found to be associated with age, hormonal influences, chemotherapy use, environmental influences, genetic predisposition, infection, and immunosuppression. The risk also appears to be altered with modern radiotherapy techniques. Practitioners of all specialties who treat cancer survivors in follow-up should be aware of this potential risk. Cancer 2016;122:1809-21. © 2016 American Cancer Society. © 2016 American Cancer Society.

  19. Research on vacuum utraviolet calibration technology

    NASA Astrophysics Data System (ADS)

    Wang, Jiapeng; Gao, Shumin; Sun, Hongsheng; Chen, Yinghang; Wei, Jianqiang

    2014-11-01

    Importance of extreme ultraviolet (EUV) and far ultraviolet (FUV) calibration is growing fast as vacuum ultraviolet payloads are wildly used in national space plan. A calibration device is established especially for the requirement of EUV and FUV metrology and measurement. Spectral radiation and detector relative spectral response at EUV and FUV wavelengths can be calibrated with accuracy of 26% and 20%, respectively. The setup of the device, theoretical model and value retroactive method are introduced and measurement of detector relative spectral response from 30 nm to 200 nm is presented in this paper. The calibration device plays an important role in national space research.

  20. A model for the spectroscopic variations of the peculiar symbiotic star MWC 560

    NASA Technical Reports Server (NTRS)

    Shore, Steven N.; Aufdenberg, Jason P.; Michalitsianos, A. G.

    1994-01-01

    In this note, we show that the ultraviolet and optical spectroscopic variability of this unique symbiotic star can be understood in terms of a time variable collimated stellar wind with a rapid acceleration near the source. Using the radial velocities observed during the ultraviolet bright phase, we find that a variation in the mass loss rate of a factor of ten can explain the ultraviolet spectral changes. The acceleration is far faster than normally observed in radiatively driven stellar winds and may be due to mechanical driving of the outflow from the disk.

  1. Extreme ultraviolet and X-ray spectroheliograph for OSO-H

    NASA Technical Reports Server (NTRS)

    Sterk, A. A.; Kieser, F.; Peck, S.; Knox, E.

    1972-01-01

    A complex scientific instrument was designed, fabricated, tested, and calibrated for launch onboard OSO-H. This instrument consisted of four spectroheliographs and an X-ray polarimeter. The instrument is designed to study solar radiation at selected wavelengths in the X-ray and the extreme ultraviolet ranges, make observations at the H-alpha wavelength, and measure the degree of polarization of X-ray emissions.

  2. Influence of photostabilizers on wood flour-HDPE composites exposed to xenon-arc radiation with and without water spray

    Treesearch

    Nicole M. Stark; Laurent M. Matuana

    2006-01-01

    The weathering of wood-plastic composites changes their appearance and/or mechanical properties. These changes can be slowed through the addition of ultraviolet absorbers and pigments. The first phase of this study examined the effect of incorporating different concentrations of an ultraviolet absorber and/or pigment into wood-flour-filled high-density polyethylene (WF...

  3. Intercomparison of global, ultraviolet B and A radiation measurements in the Dead Sea region (Ein Bokek) and Beer Sheva.

    PubMed

    Kushelevsky, A P; Kudish, A I

    1996-07-01

    Thousands of patients suffering from psoriasis have been treated successfully in the Dead Sea area by climatological methods, without medication. This high rate of success, measured in terms of partial to complete plaque clearance and reported to exceed 85% after 3-4 weeks of treatment, has been assumed to be associated with a unique ultraviolet (UV) radiation environment present in the Dead Sea region. In order to broaden our knowledge of the UV radiation environment at the Dead Sea, continuous monitoring of UV (both B and A) and global radiation has recently been initiated at two sites--Ein Bokek (located in the vicinity of the Dead Sea 375 m below mean sea level) and Beer Sheva (315 m above mean sea level)--to facilitate an intercomparison of their respective radiation intensities. The results of the first year of a detailed study of the global, UVB and UVA radiation intensities measured at both sites are summarized and reported in terms of the monthly average daily, average midday (11:00-13:00) and the corresponding maximum values. The radiation data for clear days (based upon the absolute magnitude of the global radiation) were also analyzed to perform an intercomparison between Ein Bokek and Beer Sheva for a winter month and a summer month for which all three types of radiation data were available at both sites.

  4. [Ultraviolet exposure from indoor tanning devices as a potential source of health risks: Basic knowledge of the proper use of these devices for practical users, physicians and solarium staff].

    PubMed

    Malinowska-Borowska, Jolanta; Janosik, Elżbieta

    2017-07-26

    Bearing in mind the adverse health effects of exposure to ultraviolet (UV) radiation in solarium, especially the risk of carcinogenesis, there is a need to adopt legal regulations by relevant Polish authorities. They should set out the principles for indoor tanning studios operation, supervision and service of the technical parameters of tanning devices and training programs to provide the staff with professional knowledge and other aspects of safety in these facilities. The mechanism of the harmful effects of ultraviolet radiation on the human body, scale of overexposure, resulting from excessive sunbathing are described. Methods for estimating UV exposure and possible actions aimed at reducing the overexposure and preventing from cancer development caused by UV are also presented in this paper. Med Pr 2017;68(5):653-665. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.

  5. INTERACTIONS OF CHANGING CLIMATE AND ULTRAVIOLET RADIATION IN AQUATIC AND TERRESTRIAL BIOGEOCHEMICAL CYCLES

    EPA Science Inventory

    During the past decade interest has developed in the interactive effects of climate change and UV radiation on aquatic and terrestrial biogeochemical cycles. This talk used selected case studies to illustrate approaches that are being used to investigate these intriguing processe...

  6. INTERACTIONS OF SOLAR UV RADIATION AND DISSOLVED ORGANIC MATTER IN AQUATIC ENVIRONMENTS

    EPA Science Inventory

    Changes in the ozone layer over the past two decades have resulted in increases in solar ultraviolet (UV) radiation that reaches the surface of aquatic environments. Recent studies have demonstrated that these UV increases cause changes in photochemical reactions that affect the...

  7. Extreme Ultraviolet Variability Experiment (EVE) Multiple EUV Grating Spectrographs (MEGS): Radiometric Calibrations and Results

    NASA Technical Reports Server (NTRS)

    Hock, R. A.; Woods, T. N.; Crotser, D.; Eparvier, F. G.; Woodraska, D. L.; Chamberlin, P. C.; Woods, E. C.

    2010-01-01

    The NASA Solar Dynamics Observatory (SDO), scheduled for launch in early 2010, incorporates a suite of instruments including the Extreme Ultraviolet Variability Experiment (EVE). EVE has multiple instruments including the Multiple Extreme ultraviolet Grating Spectrographs (MEGS) A, B, and P instruments, the Solar Aspect Monitor (SAM), and the Extreme ultraviolet SpectroPhotometer (ESP). The radiometric calibration of EVE, necessary to convert the instrument counts to physical units, was performed at the National Institute of Standards and Technology (NIST) Synchrotron Ultraviolet Radiation Facility (SURF III) located in Gaithersburg, Maryland. This paper presents the results and derived accuracy of this radiometric calibration for the MEGS A, B, P, and SAM instruments, while the calibration of the ESP instrument is addressed by Didkovsky et al. . In addition, solar measurements that were taken on 14 April 2008, during the NASA 36.240 sounding-rocket flight, are shown for the prototype EVE instruments.

  8. Rx for H20

    ERIC Educational Resources Information Center

    Yapijakis, Costas

    1978-01-01

    Drinking water disinfectants are discussed. Disinfectants are chlorine, chlorine dioxide, ozone, potassium permanganate, iodine, bromine, hydrogen peroxide; silver, acids and bases, ultraviolet radiation. (MR)

  9. Photoinduced currents in metal-barrier-metal junctions

    NASA Technical Reports Server (NTRS)

    Guedes, M. P.; Gustafson, T. K.; Heiblum, M.; Siu, D. P.; Slayman, C. W.; Whinnery, J. R.; Yasuoka, Y.

    1978-01-01

    The fabrication and application of metal-barrier-metal tunneling junctions for radiative interactions are discussed. Particular attention is given to the photolithographic fabrication of small area devices and the coupling to such devices via surface plasmon waves which play an important role at infrared and optical frequencies. It has been shown that the junction electron tunneling currents can be strongly coupled to surface plasmon junction modes, and spontaneous and stimulated emission of the latter are possible as well as nonlinear interactions. Finally, results demonstrating the photo-excitation of electrons with subsequent tunneling induced by ultraviolet radiation are presented. It is estimated that quantum efficiencies of the order of 5% and higher are possible in the ultraviolet region.

  10. THE ANTIGENIC POTENCY OF EPIDEMIC INFLUENZA VIRUS FOLLOWING INACTIVATION BY ULTRAVIOLET RADIATION

    PubMed Central

    Salk, Jonas E.; Lavin, G. I.; Francis, Thomas

    1940-01-01

    A study of the antigenic potency of influenza virus inactivated by ultraviolet radiation has been made. Virus so inactivated is still capable of functioning as an immunizing agent when given to mice by the intraperitoneal route. In high concentrations inactivated virus appears to be nearly as effective as active virus but when quantitative comparisons of the immunity induced by different dilutions are made, it is seen that a hundredfold loss in immunizing capacity occurs during inactivation. Virus in suspensions prepared from the lungs of infected mice is inactivated more rapidly than virus in tissue culture medium. A standard for the comparison of vaccines of epidemic influenza virus is proposed. PMID:19871057

  11. Cluster beam targets for laser plasma extreme ultraviolet and soft x-ray sources

    DOEpatents

    Kublak, G.D.; Richardson, M.C.

    1996-11-19

    Method and apparatus for producing extreme ultraviolet (EUV) and soft x-ray radiation from an ultra-low debris plasma source are disclosed. Targets are produced by the free jet expansion of various gases through a temperature controlled nozzle to form molecular clusters. These target clusters are subsequently irradiated with commercially available lasers of moderate intensity (10{sup 11}--10{sup 12} watts/cm{sup 2}) to produce a plasma radiating in the region of 0.5 to 100 nanometers. By appropriate adjustment of the experimental conditions the laser focus can be moved 10--30 mm from the nozzle thereby eliminating debris produced by plasma erosion of the nozzle. 5 figs.

  12. Non-solar ultraviolet radiation and the risk of basal and squamous cell skin cancer.

    PubMed Central

    Bajdik, C. D.; Gallagher, R. P.; Astrakianakis, G.; Hill, G. B.; Fincham, S.; McLean, D. I.

    1996-01-01

    A case-control study of non-melanocytic skin cancer was conducted among men in the province of Alberta, Canada. Two hundred and twenty-six cases of basal cell carcinoma (BCC), 180 cases of squamous cell carcinoma (SCC) and 406 age-matched controls provided information concerning skin pigmentation, occupational history, recreational activity, exposure to sunlight and sources of non-solar ultraviolet radiation (NSUVR) and other potential risk factors. Our analyses show no evidence of elevated risk for BCC or SCC among subjects exposed to various types of NSUVR. This is in opposition to studies of melanoma that have shown elevated risks for exposure to fluorescent lighting, sunlamps and sunbeds. PMID:8664139

  13. Evolution analysis of EUV radiation from laser-produced tin plasmas based on a radiation hydrodynamics model

    PubMed Central

    Su, M. G.; Min, Q.; Cao, S. Q.; Sun, D. X.; Hayden, P.; O’Sullivan, G.; Dong, C. Z.

    2017-01-01

    One of fundamental aims of extreme ultraviolet (EUV) lithography is to maximize brightness or conversion efficiency of laser energy to radiation at specific wavelengths from laser produced plasmas (LPPs) of specific elements for matching to available multilayer optical systems. Tin LPPs have been chosen for operation at a wavelength of 13.5 nm. For an investigation of EUV radiation of laser-produced tin plasmas, it is crucial to study the related atomic processes and their evolution so as to reliably predict the optimum plasma and experimental conditions. Here, we present a simplified radiation hydrodynamic model based on the fluid dynamic equations and the radiative transfer equation to rapidly investigate the evolution of radiation properties and dynamics in laser-produced tin plasmas. The self-absorption features of EUV spectra measured at an angle of 45° to the direction of plasma expansion have been successfully simulated and explained, and the evolution of some parameters, such as the plasma temperature, ion distribution and density, expansion size and velocity, have also been evaluated. Our results should be useful for further understanding of current research on extreme ultraviolet and soft X-ray source development for applications such as lithography, metrology and biological imaging. PMID:28332621

  14. Effects of solar ultraviolet radiation on coral reef organisms.

    PubMed

    Banaszak, Anastazia T; Lesser, Michael P

    2009-09-01

    Organisms living in shallow-water tropical coral reef environments are exposed to high UVR irradiances due to the low solar zenith angles (the angle of the sun from the vertical), the natural thinness of the ozone layer over tropical latitudes, and the high transparency of the water column. The hypothesis that solar ultraviolet radiation (UVR, 290-400 nm) is an important factor that affects the biology and ecology of coral reef organisms dates only to about 1980. It has been previously suggested that increased levels of biologically effective ultraviolet B radiation (UVB, 290-320 nm), which is the waveband primarily affected by ozone depletion, would have relatively small effects on corals and coral reefs and that these effects might be observed as changes in the minimum depths of occurrence of important reef taxa such as corals. This conclusion was based on predictions of increases in UVR as well as its attenuation with depth using the available data on UVR irradiances, ozone levels, and optical properties of the water overlying coral reefs. Here, we review the experimental evidence demonstrating the direct and indirect effects of UVR, both UVB and ultraviolet A (UVA, 320-400 nm) on corals and other reef associated biota, with emphasis on those studies conducted since 1996. Additionally, we re-examine the predictions made in 1996 for the increase in UVB on reefs with currently available data, assess whether those predictions were reasonable, and look at what changes might occur on coral reefs in the future as the multiple effects (i.e. increased temperature, hypercapnia, and ocean acidification) of global climate change continue.

  15. Employee factors associated with interest in improving sun protection in an Australian mining workforce.

    PubMed

    Street, Tamara D; Thomas, Drew Leighton

    2015-04-01

    As Australia experiences moderate to extreme levels of ultraviolet radiation from the sun, high participation in sun protection behaviour is required to minimise the risk of developing skin cancer. Understanding factors associated with interest in improving sun protection will enable employers to increase enrolment in sun protection programs. A cross-sectional survey was conducted at mining sites in rural Australia. The survey assessed employee demographics, stages of change and health-belief model variables, sun protection behaviour, and preferences for improving sun protection. Overall, 897 employees participated: 73% were male and 47% were classed as being at high risk of ultraviolet-related illnesses. Although 24% of high-risk participants wanted to increase their sun protection practices, only 6% wanted employer-provided sun protection assistance. Marital status and recent experience of sunburn were associated with desire to improve sun protection. Over 50% of the high-risk participants who did not want to increase their sun protection and did not want assistance were in the pre-contemplative stage of change. Self-efficacy was associated with desire to improve sun protection while susceptibility was associated with desire for assistance. The use of sun protection behaviours among this sample was low. Many employees at high risk of ultraviolet radiation exposure do not believe their approach to sun protection needs changing. SO WHAT?: Workplace health promotion programs need to educate employees about susceptibility to ultraviolet radiation exposure and develop employees' self-efficacy for sun protection behaviours. These findings can inform the content development of sun protection communication strategies targeting employees.

  16. The electronics in fluorescent bulbs and light emitting diodes (LED), rather than ultraviolet radiation, cause increased malignant melanoma incidence in indoor office workers and tanning bed users.

    PubMed

    Milham, Samuel; Stetzer, Dave

    2018-07-01

    The epidemiology of cutaneous malignant melanoma (CMM) has a number of facets that do not fit with sunlight and ultraviolet light as the primary etiologic agents. Indoor workers have higher incidence and mortality rates of CMM than outdoor workers; CMM occurs in body locations never exposed to sunlight; CMM incidence is increasing in spite of use of UV blocking agents and small changes in solar radiation. Installation of two new fluorescent lights in the milking parlor holding area of a Minnesota dairy farm in 2015 caused an immediate drop in milk production. This lead to measurement of body amperage in humans exposed to modern non-incandescent lighting. People exposed to old and new fluorescent lights, light emitting diodes (LED) and compact fluorescent lights (CFL) had body amperage levels above those considered carcinogenic. We hypothesize that modern electric lighting is a significant health hazard, a carcinogen, and is causing increasing CMM incidence in indoor office workers and tanning bed users. These lights generate dirty electricity (high frequency voltage transients), radio frequency (RF) radiation, and increase body amperage, all of which have been shown to be carcinogenic. This could explain the failure of ultraviolet blockers to stem the malignant melanoma pandemic. Tanning beds and non-incandescent lighting could be made safe by incorporating a grounded Faraday cage which allows passage of ultraviolet and visible light frequencies and blocks other frequencies. Modern electric lighting should be fabricated to be electrically clean. Copyright © 2018 Elsevier Ltd. All rights reserved.

  17. Sunscreen use and intentional exposure to ultraviolet A and B radiation: a double blind randomized trial using personal dosimeters

    PubMed Central

    Autier, P; Doré, J-F; Reis, A C; Grivegnée, A; Ollivaud, L; Truchetet, F; Chamoun, E; Rotmensz, N; Severi, G; Césarini, J-P

    2000-01-01

    A previous randomized trial found that sunscreen use could extend intentional sun exposure, thereby possibly increasing the risk of cutaneous melanoma. In a similarly designed trial, we examined the effect of the use of sunscreens having different sun protection factor (SPF) on actual exposure to ultraviolet B (UVB) and ultraviolet A (UVA) radiation. In June 1998, 58 European participants 18–24 years old were randomized to receive a SPF 10 or 30 sunscreens and were asked to complete daily records of their sun exposure during their summer holidays of whom 44 utilized a personal UVA and UVB dosimeter in a standard way during their sunbathing sessions. The median daily sunbathing duration was 2.4 hours in the SPF 10 group and 3.0 hours in the SPF 30 group (P = 0.054). The increase in daily sunbathing duration was paralleled by an increase in daily UVB exposure, but not by changes in UVA or UVB accumulated over all sunbathing sessions, or in daily UVA exposure. Of all participants, those who used the SPF 30 sunscreen and had no sunburn spent the highest number of hours in sunbathing activities. Differences between the two SPF groups in total number of sunbathing hours, daily sunbathing duration, and daily UVB exposure were largest among participants without sunburn during holidays. Among those with sunburn, the differences between the two groups tended to reduce. In conclusion, sunscreens used during sunbathing tended to increase the duration of exposures to doses of ultraviolet radiation below the sunburn threshold. © 2000 Cancer Research Campaign PMID:11027441

  18. Ultraviolet-B radiation enhancement in dielectric barrier discharge based xenon chloride exciplex source by air

    NASA Astrophysics Data System (ADS)

    Gulati, P.; Prakash, R.; Pal, U. N.; Kumar, M.; Vyas, V.

    2014-07-01

    A single barrier dielectric barrier discharge tube of quartz with multi-strip Titanium-Gold (Ti-Au) coatings have been developed and utilized for ultraviolet-B (UV-B) radiation production peaking at wavelength 308 nm. The observed radiation at this wavelength has been examined for the mixtures of the Xenon together with chlorine and air admixtures. The gas mixture composition, chlorine gas content, total gas pressure, and air pressure dependency of the UV intensity, has been analyzed. It is found that the larger concentration of Cl2 deteriorates the performance of the developed source and around 2% Cl2 in this source produced optimum results. Furthermore, an addition of air in the xenon and chlorine working gas environment leads to achieve same intensity of UV-B light but at lower working gas pressure where significant amount of gas is air.

  19. The S-layer Protein DR_2577 Binds Deinoxanthin and under Desiccation Conditions Protects against UV-Radiation in Deinococcus radiodurans

    PubMed Central

    Farci, Domenica; Slavov, Chavdar; Tramontano, Enzo; Piano, Dario

    2016-01-01

    Deinococcus radiodurans has the puzzling ability to withstand over a broad range of extreme conditions including high doses of ultraviolet radiation and deep desiccation. This bacterium is surrounded by a surface layer (S-layer) built of a regular repetition of several proteins, assembled to form a paracrystalline structure. Here we report that the deletion of a main constituent of this S-layer, the gene DR_2577, causes a decrease in the UVC resistance, especially in desiccated cells. Moreover, we show that the DR_2577 protein binds the carotenoid deinoxanthin, a strong protective antioxidant specific of this bacterium. A further spectroscopical characterization of the deinoxanthin-DR_2577 complex revealed features which could suggest a protective role of DR_2577. We propose that, especially under desiccation, the S-layer shields the bacterium from incident ultraviolet light and could behave as a first lane of defense against UV radiation. PMID:26909071

  20. The S-layer Protein DR_2577 Binds Deinoxanthin and under Desiccation Conditions Protects against UV-Radiation in Deinococcus radiodurans.

    PubMed

    Farci, Domenica; Slavov, Chavdar; Tramontano, Enzo; Piano, Dario

    2016-01-01

    Deinococcus radiodurans has the puzzling ability to withstand over a broad range of extreme conditions including high doses of ultraviolet radiation and deep desiccation. This bacterium is surrounded by a surface layer (S-layer) built of a regular repetition of several proteins, assembled to form a paracrystalline structure. Here we report that the deletion of a main constituent of this S-layer, the gene DR_2577, causes a decrease in the UVC resistance, especially in desiccated cells. Moreover, we show that the DR_2577 protein binds the carotenoid deinoxanthin, a strong protective antioxidant specific of this bacterium. A further spectroscopical characterization of the deinoxanthin-DR_2577 complex revealed features which could suggest a protective role of DR_2577. We propose that, especially under desiccation, the S-layer shields the bacterium from incident ultraviolet light and could behave as a first lane of defense against UV radiation.

  1. Collisional and radiative processes in high-pressure discharge plasmas

    NASA Astrophysics Data System (ADS)

    Becker, Kurt H.; Kurunczi, Peter F.; Schoenbach, Karl H.

    2002-05-01

    Discharge plasmas at high pressures (up to and exceeding atmospheric pressure), where single collision conditions no longer prevail, provide a fertile environment for the experimental study of collisions and radiative processes dominated by (i) step-wise processes, i.e., the excitation of an already excited atomic/molecular state and by (ii) three-body collisions leading, for instance, to the formation of excimers. The dominance of collisional and radiative processes beyond binary collisions involving ground-state atoms and molecules in such environments allows for many interesting applications of high-pressure plasmas such as high power lasers, opening switches, novel plasma processing applications and sputtering, absorbers and reflectors for electromagnetic waves, remediation of pollutants and waste streams, and excimer lamps and other noncoherent vacuum-ultraviolet light sources. Here recent progress is summarized in the use of hollow cathode discharge devices with hole dimensions in the range 0.1-0.5 mm for the generation of vacuum-ultraviolet light.

  2. Effects of radiation and temperature on gallium nitride (GaN) metal-semiconductor-metal ultraviolet photodetectors

    NASA Astrophysics Data System (ADS)

    Chiamori, Heather C.; Angadi, Chetan; Suria, Ateeq; Shankar, Ashwin; Hou, Minmin; Bhattacharya, Sharmila; Senesky, Debbie G.

    2014-06-01

    The development of radiation-hardened, temperature-tolerant materials, sensors and electronics will enable lightweight space sub-systems (reduced packaging requirements) with increased operation lifetimes in extreme harsh environments such as those encountered during space exploration. Gallium nitride (GaN) is a ceramic, semiconductor material stable within high-radiation, high-temperature and chemically corrosive environments due to its wide bandgap (3.4 eV). These material properties can be leveraged for ultraviolet (UV) wavelength photodetection. In this paper, current results of GaN metal-semiconductor-metal (MSM) UV photodetectors behavior after irradiation up to 50 krad and temperatures of 15°C to 150°C is presented. These initial results indicate that GaN-based sensors can provide robust operation within extreme harsh environments. Future directions for GaN-based photodetector technology for down-hole, automotive and space exploration applications are also discussed.

  3. Upper limits to the interstellar radiation field between 775 and 1050 A

    NASA Technical Reports Server (NTRS)

    Paresce, F.; Bowyer, S.

    1976-01-01

    A 40-A resolution extreme-ultraviolet spectrometer, sensitive to radiation in the 775-1050 A band, was flown on a Black Brant VC rocket to measure the night sky brightness in this region of the electromagnetic spectrum. A weak signal above background was recorded in most channels as the spectrometer's field of view scanned the sky in the vicinity of the galactic plane from Monoceros to Andromeda. Because the earth's upper atmosphere may produce some radiation in this wavelength region, the possibility cannot be excluded that some or all of the observed signal is terrestrial in origin. However, observational upper limits can be established at the 95-per cent confidence level for the intensity of an extraterrestrial extreme ultraviolet background which ranges from 6 millionths erg/sq cm/s/sr/A at 1050 A to 4 ten-millionths erg/sq cm/s/sr/A at 775 A. These results are consistent with existing theoretical predictions.

  4. Investigation of degradation mechanisms in composite matrices

    NASA Technical Reports Server (NTRS)

    Giori, C.; Yamauchi, T.

    1982-01-01

    Degradation mechanisms were investigated for graphite/polysulfone and graphite/epoxy laminates exposed to ultraviolet and high-energy electron radiations in vacuum up to 960 equivalent sun hours and 10 to the ninth power rads respectively. Based on GC and combined GC/MS analysis of volatile by-products evolved during irradiation, several free radical mechanisms of composite degradation were identified. The radiation resistance of different matrices was compared in terms of G values and quantum yields for gas formation. All the composite materials evaluated show high electron radiation stability and relatively low ultraviolet stability as indicated by low G values and high quantum for gas formation. Mechanical property measurements of irradiated samples did not reveal significant changes, with the possible exception of UV exposed polysulfone laminates. Hydrogen and methane were identified as the main by-products of irradiation, along with unexpectedly high levels of CO and CO2.

  5. Ultraviolet-B radiation enhancement in dielectric barrier discharge based xenon chloride exciplex source by air

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gulati, P., E-mail: pgulati1512@gmail.com; Department of Physics, Banasthali University, P.O. Banasthali Vidyapith, Rajasthan 304022; Prakash, R.

    2014-07-07

    A single barrier dielectric barrier discharge tube of quartz with multi-strip Titanium-Gold (Ti-Au) coatings have been developed and utilized for ultraviolet-B (UV-B) radiation production peaking at wavelength 308 nm. The observed radiation at this wavelength has been examined for the mixtures of the Xenon together with chlorine and air admixtures. The gas mixture composition, chlorine gas content, total gas pressure, and air pressure dependency of the UV intensity, has been analyzed. It is found that the larger concentration of Cl{sub 2} deteriorates the performance of the developed source and around 2% Cl{sub 2} in this source produced optimum results. Furthermore, anmore » addition of air in the xenon and chlorine working gas environment leads to achieve same intensity of UV-B light but at lower working gas pressure where significant amount of gas is air.« less

  6. Ultraviolet damage to the eye revisited: eye-sun protection factor (E-SPF®), a new ultraviolet protection label for eyewear.

    PubMed

    Behar-Cohen, Francine; Baillet, Gilles; de Ayguavives, Tito; Garcia, Paula Ortega; Krutmann, Jean; Peña-García, Pablo; Reme, Charlotte; Wolffsohn, James S

    2014-01-01

    Ultraviolet (UV) radiation potentially damages the skin, the immune system, and structures of the eye. A useful UV sun protection for the skin has been established. Since a remarkable body of evidence shows an association between UV radiation and damage to structures of the eye, eye protection is important, but a reliable and practical tool to assess and compare the UV-protective properties of lenses has been lacking. Among the general lay public, misconceptions on eye-sun protection have been identified. For example, sun protection is mainly ascribed to sunglasses, but less so to clear lenses. Skin malignancies in the periorbital region are frequent, but usual topical skin protection does not include the lids. Recent research utilized exact dosimetry and demonstrated relevant differences in UV burden to the eye and skin at a given ambient irradiation. Chronic UV effects on the cornea and lens are cumulative, so effective UV protection of the eyes is important for all age groups and should be used systematically. Protection of children's eyes is especially important, because UV transmittance is higher at a very young age, allowing higher levels of UV radiation to reach the crystalline lens and even the retina. Sunglasses as well as clear lenses (plano and prescription) effectively reduce transmittance of UV radiation. However, an important share of the UV burden to the eye is explained by back reflection of radiation from lenses to the eye. UV radiation incident from an angle of 135°-150° behind a lens wearer is reflected from the back side of lenses. The usual antireflective coatings considerably increase reflection of UV radiation. To provide reliable labeling of the protective potential of lenses, an eye-sun protection factor (E-SPF®) has been developed. It integrates UV transmission as well as UV reflectance of lenses. The E-SPF® compares well with established skin-sun protection factors and provides clear messages to eye health care providers and to lay consumers.

  7. Early exposure to ultraviolet-B radiation decreases immune function later in life

    PubMed Central

    Ceccato, Emma; Cramp, Rebecca L.; Seebacher, Frank; Franklin, Craig E.

    2016-01-01

    Amphibians have declined dramatically worldwide. Many of these declines are occurring in areas where no obvious anthropogenic stressors are present. It is proposed that in these areas, environmental factors such as elevated solar ultraviolet-B (UV-B) radiation could be responsible. Ultraviolet-B levels have increased in many parts of the world as a consequence of the anthropogenic destruction of the ozone layer. Amphibian tadpoles are particularly sensitive to the damaging effects of UV-B radiation, with exposure disrupting growth and fitness in many species. Given that UV-B can disrupt immune function in other animals, we tested the hypothesis that early UV-B exposure suppresses the immune responses of amphibian tadpoles and subsequent juvenile frogs. We exposed Limnodynastes peronii tadpoles to sublethal levels of UV-B radiation for 6 weeks after hatching, then examined indices of immune function in both the tadpoles and the subsequent metamorphs. There was no significant effect of UV-B on tadpole leucocyte counts or on their response to an acute antigen (phytohaemagglutinin) challenge. However, early UV-B exposure resulted in a significant reduction in both metamorph leucocyte abundance and their response to an acute phytohaemagglutinin challenge. These data demonstrate that early UV-B exposure can have carry-over effects on later life-history traits even if the applied stressor has no immediately discernible effect. These findings have important implications for our understanding of the effects of UV-B exposure on amphibian health and susceptibility to diseases such as chytridiomycosis. PMID:27668081

  8. AMBIENT SOLAR UV RADIATION CAUSES MORTALITY IN LARVAE OF THREE SPECIES OF RANA

    EPA Science Inventory

    Recent reports concerning the lethal effects of solar ultraviolet-B (UV-B) radiation on amphibians suggest that this stressor has the potential to impact some amphibian populations. In this study embryos and larvae of three anuran species, Rana pipiens, R. clamitans, and R. septe...

  9. EVALUATION OF BARRIERS TO THE USE OF RADIATION CURED COATINGS IN WIDE-WEB FLEXOGRAPHIC PRINTING

    EPA Science Inventory

    The report gives results of a study to investigate and identify the technical, economic, and educational barriers to the use and implementation of radiation-curable coatings (primarily ultraviolet (UV) curable inks) in the wide-web flexographic printing industry. (NOTE: In suppor...

  10. SUPPLEMENTAL ULTRAVIOLET-B RADIATION DOES NOT REDUCE GROWTH OR GRAIN YIELD IN RICE

    EPA Science Inventory

    Negative effects of enhanced UV-B radiation have been demonstrated in plants, but impacts under realistic field conditions remain uncertain. Adverse impacts to major crops, such as rice (Oryza sativa L.), that are grown in areas with currently high ambient levels of UV-B, could h...

  11. Production of Chromophoric Dissolved Organic Matter from Mangrove Leaf Litter and Floating Sargassum Colonies

    EPA Science Inventory

    Chromophoric dissolved organic matter (CDOM) strongly absorbs solar radiation in the blue-green and serves as the primary attenuator of water column ultraviolet radiation (UV-R). CDOM interferes with remote sensing of ocean chlorophyll and can control UV-R-induced damage to light...

  12. Hawking radiation from the holographic screen

    NASA Astrophysics Data System (ADS)

    Zhao, Ying-Jie

    2017-10-01

    In this paper, we generalize the Parikh-Wilczek scheme to a holographic screen in the framework of the ultraviolet self-complete quantum gravity. We calculate that the tunneling probability depends on the energy of the particle and the mass of the holographic screen. The radiating temperature has not been the standard Hawking temperature.

  13. COMPARATIVE SENSITIVITY OF BINUCLEATE AND TRINUCLEATE POLLEN TO ULTRAVIOLET RADIATION: A THEORETICAL PERSPECTIVE

    EPA Science Inventory

    Angiosperm pollen shed in the binucleate condition (which is the case for most species) may be more susceptible to UV radiation damage than pollen shed in the trinucleate condition. The speculation is supported by data summarized from the literature which show that trinucleate po...

  14. Plant Phenolics as Radiation Protectants For The Beet Armyworm (Lepidoptera: Noctuidae) Nucleopolyhedrovirus

    USDA-ARS?s Scientific Manuscript database

    Thirteen phenolics were tested as ultraviolet (UV) protectants for the nucleopolyhedrovirus (SeMNPV) of the beet armyworm, Spodoptera exigua (Hübner). After 30 minute exposure to UVB/UVB radiation, eleven SeMNPV/phenolic combinations provided good to excellent UV protection when used at a concentra...

  15. Possibility of the amplification of the radiation at the wave length lambda = 1776 A in recombining plasma (in Russian)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gudzenko, L.I.; Evstigneev, V.V.; Yakovlenko, S.I.

    1973-09-01

    A calculation is made of the characteristics of the amplification of the radiation in the vaccum ultraviolet spectral range in the 2s-2p transition of Be ions in supercooled (intensely recombining) dense Be plasma. (tr-auth)

  16. Source of coherent short wavelength radiation

    DOEpatents

    Villa, Francesco

    1990-01-01

    An apparatus for producing coherent radiation ranging from X-rays to the far ultraviolet (i.e., 1 Kev to 10 eV) utilizing the Compton scattering effect. A photon beam from a laser is scattered on a high energy electron bunch from a pulse power linac. The short wavelength radiation produced by such scattering has sufficient intensity and spatial coherence for use in high resolution applications such as microscopy.

  17. Dihydroxyacetone: A Review.

    PubMed

    Braunberger, Taylor L; Nahhas, Amanda F; Katz, Linda M; Sadrieh, Nakissa; Lim, Henry W

    2018-04-01

    The sunless tanning industry has experienced rapid growth due to public education on the dangers of ultraviolet radiation on skin and improvements in products. Dihydroxyacetone (DHA) is a 3-carbon sugar allowed by the Food and Drug Administration (FDA) as a color additive in sunless tanning products. Bronzers, a product removed with soap and water, may also contain DHA. We aim to review the literature on DHA. DHA is intended for external application, not including the mucous membranes or in or around the eye area. DHA has been used in spray-tan booths and by airbrushing it onto consumers, although these are unapproved uses, as contact with the color additive is not restricted to the external part of the body. Consequently, the FDA recommends customers shield their eyes, lips, and mucous membranes, as well as refrain from ingestion or inhalation of DHA. Unlike sunscreens, products that protect against ultraviolet radiation and are regulated by the FDA as non-prescription drugs, sunless tanning products are regulated as cosmetics and cannot provide any protection from exposure to ultraviolet radiation. There are reports of non-cosmetic uses of DHA that are not FDA approved. With the wide-spread use of DHA, additional studies on its safety are warranted.

    J Drugs Dermatol. 2018;17(4):387-391.

    .

  18. Ultraviolet-visible and fluorescence spectroscopy can be used as a diagnostic tool for gamma irradiation detection in vivo.

    PubMed

    K-Abdelhalim, Mohamed Anwar; Moussa, Sherif A-Abdelmottaleb

    2016-09-01

    The spectroscopic properties can indicate important features about the nature and severity of the disease. However, no earlier studies have been used the spectroscopic properties as a diagnostic tool for radiation detection. This study was aimed to use ultraviolet-visible and fluorescence spectroscopy as a diagnostic tool for gamma irradiation detection in rats in vivo. Adult male rats were exposed to 25, 50, 75 and 100 Gray as single dose, using Cobalt-60 (Co-60) source with a dose rate of 0.883 centi Gray/sec (cGy/s). Ultraviolet and fluorescence spectroscopy of rat's blood serum were measured. After gamma irradiation of rats in vivo, the blood serum absorbance peaks for 25, 50, 75 and 100 Gray (Gy) decreased and shifted towards the ultra violet wavelength. A maximal change in fluorescence intensity of blood serum at 350 nm was obtained when exciting light at 194 nm after irradiation. The fluorescence intensity also decreased with the dose. The highest radiation gamma dose might be accompanied with the highest oxidative stress. This study suggests that at the above mentioned gamma radiation doses, the blood is highly fragmented; with low aggregation at 25 Gy and with high aggregation at 50-100 Gy.

  19. KSC-97PC1009

    NASA Image and Video Library

    1997-07-07

    The International Extreme Ultraviolet Hitchhiker-2 (IEH-2) payload rests in a work stand in the Space Station Processing Facility prior to its trip out to Launch Pad 39A for installation into the payload bay of the Space Shuttle Orbiter Discovery for the STS-85 mission. The IEH-2 experiments will study ultraviolet radiation from stars, the sun and in the solar system. The Technology Applications and Science-1 (TAS-1) payload is another series of experiments that will be conducted during the 11-day mission in Discovery’s payload bay. The TAS-1 holds seven separate experiments that will provide data on the Earth’s topography and atmosphere, study the sun’s energy, and test new thermal control devices, as well as several student-developed experiments. Other STS-85 payloads include the Cryogenic Infrared Spectrometers and Telescopes for the Atmosphere-Shuttle Pallet Satellite-2 (CRISTA-SPAS-2). The CRISTA is a system of three telescopes and four spectrometers to measure infrared radiation emitted by the Earth’s middle atmosphere. The CRISTA-SPAS-2 free-flying satellite will be deployed from Discovery and retrieved later in the flight. Also onboard the satellite will be the Middle Atmosphere High Resolution Spectrograph Investigation (MAHRSI) to measure ultraviolet radiation emitted and scattered by the Earth’s atmosphere

  20. KSC-97PC1030

    NASA Image and Video Library

    1997-07-10

    KENNEDY SPACE CENTER, Fla. -- The payload canister containing the Cryogenic Infrared Spectrometers and Telescopes for the Atmosphere-Shuttle Pallet Satellite-2 (CRISTA-SPAS-2) payload for the STS-85 mission is hoisted to the Payload Changeout Room (PCR) at Launch Pad 39A. Also in the canister are the Technology Applications and Science-1 (TAS-1) and International Extreme Ultraviolet Hitchhiker-2 (IEH-2) payloads. All three will be transferred from the PCR into the payload bay of the Space Shuttle Orbiter Discovery after the space vehicle arrives at the pad. The CRISTA is a system of three telescopes and four spectrometers to measure infrared radiation emitted by the Earth’s middle atmosphere. During the 11-day mission, the CRISTA-SPAS-2 free-flying satellite will be deployed from Discovery and retrieved later in the flight. Also onboard the satellite will be the Middle Atmosphere High Resolution Spectrograph Investigation (MAHRSI) to measure ultraviolet radiation emitted and scattered by the Earth’s atmosphere. The TAS-1 holds seven separate experiments that will provide data on the Earth’s topography and atmosphere, study the sun’s energy, and test new thermal control devices, as well as several student-developed experiments. The IEH-2 experiments will study ultraviolet radiation from stars, the sun and in the solar system

Top