De novo giant A2 aneurysm following anterior communicating artery occlusion.
Ibrahim, Tarik F; Hafez, Ahmad; Andrade-Barazarte, Hugo; Raj, Rahul; Niemela, Mika; Lehto, Hanna; Numminen, Jussi; Jarvelainen, Juha; Hernesniemi, Juha
2015-01-01
De novo intracranial aneurysms are reported to occur with varying incidence after intracranial aneurysm treatment. They are purported to be observed, however, with increased incidence after Hunterian ligation; particularly in cases of carotid artery occlusion for giant or complex aneurysms deemed unclippable. We report a case of right-sided de novo giant A2 aneurysm 6 years after an anterior communicating artery (ACoA) aneurysm clipping. We believe this de novo aneurysm developed in part due to patient-specific risk factors but also a significant change in cerebral hemodynamics. The ACoA became occluded after surgery that likely altered the cerebral hemodynamics and contributed to the de novo aneurysm. We believe this to be the first reported case of a giant de novo aneurysm in this location. Following parent vessel occlusion (mostly of the carotid artery), there are no reports of any de novo aneurysms in the pericallosal arteries let alone a giant one. The patient had a dominant right A1 and the sudden increase in A2 blood flow likely resulted in increased wall shear stress, particularly in the medial wall of the A2 where the aneurysm occurred 2 mm distal to the A1-2 junction. ACoA preservation is a key element of aneurysm surgery in this location. Suspected occlusion of this vessel may warrant closer radiographic follow-up in patients with other risk factors for aneurysm development.
Intraoperative sonographic assessment of graft patency during extracranial-intracranial bypass.
Badie, B; Lee, F T; Pozniak, M A; Strother, C M
2000-09-01
Extracranial-intracranial (EC-IC) bypass may be necessary to facilitate treatment of unclippable posterior circulation fusiform aneurysms. Although intraoperative digital subtraction angiography (DSA) allows assessment of graft patency, this technique, because of difficulties inherent in performing selective catheterization and angiography in the operating room, has limitations. Duplex sonography, in contrast, is easily performed, and provides information regarding graft patency and blood flow direction during EC-IC bypass procedures. This latter information proved useful in determining the time of parent artery occlusion after two EC-IC bypass procedures performed for treatment of a fusiform midbasilar artery aneurysm.
International Registry for Patients With Castleman Disease
2017-07-12
Castleman Disease; Castleman's Disease; Giant Lymph Node Hyperplasia; Angiofollicular Lymph Hyperplasia; Angiofollicular Lymph Node Hyperplasia; Angiofollicular Lymphoid Hyperplasia; GLNH; Hyperplasia, Giant Lymph Node; Lymph Node Hyperplasia, Giant
Gravity modes as a way to distinguish between hydrogen- and helium-burning red giant stars.
Bedding, Timothy R; Mosser, Benoit; Huber, Daniel; Montalbán, Josefina; Beck, Paul; Christensen-Dalsgaard, Jørgen; Elsworth, Yvonne P; García, Rafael A; Miglio, Andrea; Stello, Dennis; White, Timothy R; De Ridder, Joris; Hekker, Saskia; Aerts, Conny; Barban, Caroline; Belkacem, Kevin; Broomhall, Anne-Marie; Brown, Timothy M; Buzasi, Derek L; Carrier, Fabien; Chaplin, William J; Di Mauro, Maria Pia; Dupret, Marc-Antoine; Frandsen, Søren; Gilliland, Ronald L; Goupil, Marie-Jo; Jenkins, Jon M; Kallinger, Thomas; Kawaler, Steven; Kjeldsen, Hans; Mathur, Savita; Noels, Arlette; Aguirre, Victor Silva; Ventura, Paolo
2011-03-31
Red giants are evolved stars that have exhausted the supply of hydrogen in their cores and instead burn hydrogen in a surrounding shell. Once a red giant is sufficiently evolved, the helium in the core also undergoes fusion. Outstanding issues in our understanding of red giants include uncertainties in the amount of mass lost at the surface before helium ignition and the amount of internal mixing from rotation and other processes. Progress is hampered by our inability to distinguish between red giants burning helium in the core and those still only burning hydrogen in a shell. Asteroseismology offers a way forward, being a powerful tool for probing the internal structures of stars using their natural oscillation frequencies. Here we report observations of gravity-mode period spacings in red giants that permit a distinction between evolutionary stages to be made. We use high-precision photometry obtained by the Kepler spacecraft over more than a year to measure oscillations in several hundred red giants. We find many stars whose dipole modes show sequences with approximately regular period spacings. These stars fall into two clear groups, allowing us to distinguish unambiguously between hydrogen-shell-burning stars (period spacing mostly ∼ 50 seconds) and those that are also burning helium (period spacing ∼ 100 to 300 seconds).
NASA Astrophysics Data System (ADS)
Hekker, S.; Christensen-Dalsgaard, J.
2017-06-01
The internal properties of stars in the red-giant phase undergo significant changes on relatively short timescales. Long near-uninterrupted high-precision photometric timeseries observations from dedicated space missions such as CoRoT and Kepler have provided seismic inferences of the global and internal properties of a large number of evolved stars, including red giants. These inferences are confronted with predictions from theoretical models to improve our understanding of stellar structure and evolution. Our knowledge and understanding of red giants have indeed increased tremendously using these seismic inferences, and we anticipate that more information is still hidden in the data. Unraveling this will further improve our understanding of stellar evolution. This will also have significant impact on our knowledge of the Milky Way Galaxy as well as on exo-planet host stars. The latter is important for our understanding of the formation and structure of planetary systems.
NASA Astrophysics Data System (ADS)
Rainville, E. J.; Walter, R. K.; Leary, P.; Woodson, C. B.; Monismith, S. G.; Nickols, K. J.
2017-12-01
Kelp forests are one of the most vibrant and productive ecosystems in the California coastal ocean and the health of these ecosystems is heavily influenced by the local hydrodynamics. In southern Monterey Bay, the nearshore environment is characterized by large areas of rocky reef and giant kelp (Macrocystis pyrifera) forests. The physical environment at this location is dominated by nearshore internal bores, which produce transient stratification and mixing events associated with the delivery of subthermocline waters to shallow regions. During the spring of 2013, a large array of oceanographic moorings measuring temperature and velocity at an extremely high spatiotemporal resolution was deployed to investigate the role of rocky reefs and giant kelp forests on the cross-shelf propagation of shoaling internal waves and bores. We take advantage of a unique site location where a rocky reef with giant kelp was located adjacent to a large sandy channel to compare temperature dynamics and flow both inside and outside the kelp forest. Preliminary analysis suggests that the rocky reef and kelp forest act to limit the cross-shelf extent of the internal bore features and dampen temperature variance at higher frequencies when compared to the adjacent sand channel. Moreover, by defining an internal bore strength index, we will explore temperature and velocity dynamics with and without internal bore forcing along the two cross-shelf transects (i.e., rocky reef and sandy channel transects).
The possibility of giant dielectric materials for multilayer ceramic capacitors.
Ishii, Tatsuya; Endo, Makoto; Masuda, Kenichiro; Ishida, Keisuke
2013-02-11
There have been numerous reports on discovery of giant dielectric permittivity materials called internal barrier layer capacitor in the recent years. We took particular note of one of such materials, i.e., BaTiO 3 with SiO 2 coating. It shows expressions of giant electric permittivity when processed by spark plasma sintering. So we evaluated various electrical characteristics of this material to find out whether it is applicable to multilayer ceramic capacitors. Our evaluation revealed that the isolated surface structure is the sole cause of expressions of giant dielectric permittivity.
Surface Compositions of Red Giant Stars in Globular Clusters
NASA Astrophysics Data System (ADS)
Cheng, Eric; Lau, Marie; Smith, Graeme; Chen, Brian
2018-01-01
Globular clusters (GCs) are excellent “laboratories” to study the formation and evolution of our galaxy. In order to understand, more specifically, the chemical compositions and stellar evolution of the stars in GCs, we ask whether or not deep internal mixing occurs in red giants or if in fact the compositions come from the primordial interstellar medium or previous generations of stars. It has been discovered that as a star evolves up the red giant branch, the surface carbon abundance decreases, which is evidence of deep internal mixing. We questioned whether these processes also affect O or Na abundance as a star evolves. We collected measurement data of red giants from GCs out of academic journals and sorted the data into catalogs. Then, we plotted the catalogs into figures, comparing surface O and Na each with stellar luminosity. Statistical tests were ran to quantify the amount of correlation between the variables. Out of 27 GCs, we concluded that eight show a positive correlation between Na and luminosity, and two show a negative correlation between O and luminosity. Properties of GCs were compared to determine if chemical distribution in stars depends on GCs as the self-enrichment scenario suggests. We created histograms of sodium distribution to test for bimodality to examine if there are separate trends in each GC. In six GCs, two different sequences of red giants appear for Na versus luminosity, suggesting evidence that the depth of mixing may differ among each red giant in a GC. This study has provided new evidence that the changing chemical abundances on the surfaces of red giants can be due to stellar evolutionary effects and deep internal mixing, which may not necessarily depend on the GC and may differ in depth among each red giant. Through this study, we learn more about stellar evolution which will eventually help us understand the origins of our universe. Most of this work was carried out by high school students working under the auspices of the Science Internship Program (SIP) at UC Santa Cruz.
Colossal internal barrier layer capacitance effect in polycrystalline copper (II) oxide
NASA Astrophysics Data System (ADS)
Sarkar, Sudipta; Jana, Pradip Kumar; Chaudhuri, B. K.
2008-01-01
Dielectric spectroscopy analysis of the high permittivity (κ˜104) copper (II) oxide (CuO) ceramic shows that the grain contribution plays a major role for the giant-κ value at low temperature, whereas grain boundary (GB) contribution dominates around room temperature and above. Moreover, impedance spectroscopy analysis reveals electrically heterogeneous microstructure in CuO consisting of semiconducting grains and insulating GBs. Finally, the giant dielectric phenomenon exhibited by CuO is attributed to the internal barrier layer (due to GB) capacitance mechanism.
Asteroseismology can reveal strong internal magnetic fields in red giant stars.
Fuller, Jim; Cantiello, Matteo; Stello, Dennis; Garcia, Rafael A; Bildsten, Lars
2015-10-23
Internal stellar magnetic fields are inaccessible to direct observations, and little is known about their amplitude, geometry, and evolution. We demonstrate that strong magnetic fields in the cores of red giant stars can be identified with asteroseismology. The fields can manifest themselves via depressed dipole stellar oscillation modes, arising from a magnetic greenhouse effect that scatters and traps oscillation-mode energy within the core of the star. The Kepler satellite has observed a few dozen red giants with depressed dipole modes, which we interpret as stars with strongly magnetized cores. We find that field strengths larger than ~10(5) gauss may produce the observed depression, and in one case we infer a minimum core field strength of ≈10(7) gauss. Copyright © 2015, American Association for the Advancement of Science.
The International Outer Planets Watch atmospheres node database of giant-planet images
NASA Astrophysics Data System (ADS)
Hueso, R.; Legarreta, J.; Sánchez-Lavega, A.; Rojas, J. F.; Gómez-Forrellad, J. M.
2011-10-01
The Atmospheres Node of the International Outer Planets Watch (IOPW) is aimed to encourage the observations and study of the atmospheres of the Giant Planets. One of its main activities is to provide an interaction between the professional and amateur astronomical communities maintaining an online and fully searchable database of images of the giant planets obtained from amateur astronomers and available to both professional and amateurs [1]. The IOPW database contains about 13,000 image observations of Jupiter and Saturn obtained in the visible range with a few contributions of Uranus and Neptune. We describe the organization and structure of the database as posted in the Internet and in particular the PVOL software (Planetary Virtual Observatory & Laboratory) designed to manage the site and based in concepts from Virtual Observatory projects.
Ultrafast Electric Field Pulse Control of Giant Temperature Change in Ferroelectrics
DOE Office of Scientific and Technical Information (OSTI.GOV)
Qi, Y.; Liu, S.; Lindenberg, A. M.
There is a surge of interest in developing environmentally friendly solid-state-based cooling technology. Here, we point out that a fast cooling rate (≈ 10 11 K/s) can be achieved by driving solid crystals to a high-temperature phase with a properly designed electric field pulse. Specifically, we predict that an ultrafast electric field pulse can cause a giant temperature decrease up to 32 K in PbTiO 3 occurring on few picosecond time scales. Here, we explain the underlying physics of this giant electric field pulse-induced temperature change with the concept of internal energy redistribution: the electric field does work on amore » ferroelectric crystal and redistributes its internal energy, and the way the kinetic energy is redistributed determines the temperature change and strongly depends on the electric field temporal profile. This concept is supported by our all-atom molecular dynamics simulations of PbTiO 3 and BaTiO 3. Moreover, this internal energy redistribution concept can also be applied to understand electrocaloric effect. We further propose new strategies for inducing giant cooling effect with ultrafast electric field pulse. This Letter offers a general framework to understand electric-field-induced temperature change and highlights the opportunities of electric field engineering for controlled design of fast and efficient cooling technology.« less
Ultrafast Electric Field Pulse Control of Giant Temperature Change in Ferroelectrics
Qi, Y.; Liu, S.; Lindenberg, A. M.; ...
2018-01-30
There is a surge of interest in developing environmentally friendly solid-state-based cooling technology. Here, we point out that a fast cooling rate (≈ 10 11 K/s) can be achieved by driving solid crystals to a high-temperature phase with a properly designed electric field pulse. Specifically, we predict that an ultrafast electric field pulse can cause a giant temperature decrease up to 32 K in PbTiO 3 occurring on few picosecond time scales. Here, we explain the underlying physics of this giant electric field pulse-induced temperature change with the concept of internal energy redistribution: the electric field does work on amore » ferroelectric crystal and redistributes its internal energy, and the way the kinetic energy is redistributed determines the temperature change and strongly depends on the electric field temporal profile. This concept is supported by our all-atom molecular dynamics simulations of PbTiO 3 and BaTiO 3. Moreover, this internal energy redistribution concept can also be applied to understand electrocaloric effect. We further propose new strategies for inducing giant cooling effect with ultrafast electric field pulse. This Letter offers a general framework to understand electric-field-induced temperature change and highlights the opportunities of electric field engineering for controlled design of fast and efficient cooling technology.« less
Ultrafast Electric Field Pulse Control of Giant Temperature Change in Ferroelectrics
NASA Astrophysics Data System (ADS)
Qi, Y.; Liu, S.; Lindenberg, A. M.; Rappe, A. M.
2018-01-01
There is a surge of interest in developing environmentally friendly solid-state-based cooling technology. Here, we point out that a fast cooling rate (≈1011 K /s ) can be achieved by driving solid crystals to a high-temperature phase with a properly designed electric field pulse. Specifically, we predict that an ultrafast electric field pulse can cause a giant temperature decrease up to 32 K in PbTiO3 occurring on few picosecond time scales. We explain the underlying physics of this giant electric field pulse-induced temperature change with the concept of internal energy redistribution: the electric field does work on a ferroelectric crystal and redistributes its internal energy, and the way the kinetic energy is redistributed determines the temperature change and strongly depends on the electric field temporal profile. This concept is supported by our all-atom molecular dynamics simulations of PbTiO3 and BaTiO3 . Moreover, this internal energy redistribution concept can also be applied to understand electrocaloric effect. We further propose new strategies for inducing giant cooling effect with ultrafast electric field pulse. This Letter offers a general framework to understand electric-field-induced temperature change and highlights the opportunities of electric field engineering for controlled design of fast and efficient cooling technology.
Ma, Ben; Lei, Shuo; Qing, Qin; Wen, Yali
2018-01-01
Simple Summary This study evaluates the effect of local, regional, and global factors on the recovery of giant panda populations and their habitat, questioning the recent downgrading in the conservation status of this iconic species. We highlight the actions taken over the last decade, which were primarily local scale changes and efforts for protecting pandas. Broader regional development and global climate change are expected to negatively affect current population trends in the long-term; this phenomenon has been documented in other wildlife populations also showing a recent recovery. Thus, we call for a revision of the assessments stipulated by the International Union for Conservation of Nature to incorporate broader potential impacts in predicting the future survival of threatened populations, thereby, ensuring that appropriate and objective protection measures are implemented well in advance. Abstract The International Union for Conservation of Nature (IUCN) reduced the threat status of the giant panda from “endangered” to “vulnerable” in September 2016. In this study, we analyzed current practices for giant panda conservation at regional and local environmental scales, based on recent reports of giant panda protection efforts in Sichuan Province, China, combined with the survey results from 927 households within and adjacent to the giant panda reserves in this area. The results showed that household attitudes were very positive regarding giant panda protection efforts. Over the last 10 years, farmers’ dependence on the natural resources provided by giant panda reserves significantly decreased. However, socio-economic development increased resource consumption, and led to climate change, habitat fragmentation, environmental pollution, and other issues that placed increased pressure on giant panda populations. This difference between local and regional scales must be considered when evaluating the IUCN status of giant pandas. While the status of this species has improved in the short-term due to positive local attitudes, large-scale socio-economic development pressure could have long-term negative impacts. Consequently, the IUCN assessment leading to the classification of giant panda as “vulnerable” instead of “endangered”, should not affect its conservation intensity and effort, as such actions could negatively impact population recovery efforts, leading to the extinction of this charismatic species. PMID:29751488
Convection and Dynamo Action in Ice Giant Dynamo Models with Electrical Conductivity Stratification
NASA Astrophysics Data System (ADS)
Soderlund, K. M.; Featherstone, N. A.; Heimpel, M. H.; Aurnou, J. M.
2017-12-01
Uranus and Neptune are relatively unexplored, yet critical for understanding the physical and chemical processes that control the behavior and evolution of giant planets. Because their multipolar magnetic fields, three-jet zonal winds, and extreme energy balances are distinct from other planets in our Solar System, the ice giants provide a unique opportunity to test hypotheses for internal dynamics and magnetic field generation. While it is generally agreed that dynamo action in the ionic ocean generates their magnetic fields, the mechanisms that control the morphology, strength, and evolution of the dynamos - which are likely distinct from those in the gas giants and terrestrial planets - are not well understood. We hypothesize that the dynamos and zonal winds are dynamically coupled and argue that their characteristics are a consequence of quasi-three-dimensional turbulence in their interiors. Here, we will present new dynamo simulations with an inner electrically conducting region and outer electrically insulating layer to self-consistently couple the ionic oceans and molecular envelopes of these planets. For each simulation, the magnetic field morphology and amplitude, zonal flow profile, and internal heat flux pattern will be compared against corresponding observations of Uranus and Neptune. We will also highlight how these simulations will both contribute to and benefit from a future ice giant mission.
SEISMIC DIAGNOSTICS OF RED GIANTS: FIRST COMPARISON WITH STELLAR MODELS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Montalban, J.; Miglio, A.; Noels, A.
2010-10-01
The clear detection with CoRoT and KEPLER of radial and non-radial solar-like oscillations in many red giants paves the way for seismic inferences on the structure of such stars. We present an overview of the properties of the adiabatic frequencies and frequency separations of radial and non-radial oscillation modes for an extended grid of models. We highlight how their detection allows a deeper insight into the internal structure and evolutionary state of red giants. In particular, we find that the properties of dipole modes constitute a promising seismic diagnostic tool of the evolutionary state of red giant stars. We comparemore » our theoretical predictions with the first 34 days of KEPLER data and predict the frequency diagram expected for red giants in the CoRoT exofield in the galactic center direction.« less
Internal rotation of 13 low-mass low-luminosity red giants in the Kepler field
NASA Astrophysics Data System (ADS)
Triana, S. A.; Corsaro, E.; De Ridder, J.; Bonanno, A.; Pérez Hernández, F.; García, R. A.
2017-06-01
Context. The Kepler space telescope has provided time series of red giants of such unprecedented quality that a detailed asteroseismic analysis becomes possible. For a limited set of about a dozen red giants, the observed oscillation frequencies obtained by peak-bagging together with the most recent pulsation codes allowed us to reliably determine the core/envelope rotation ratio. The results so far show that the current models are unable to reproduce the rotation ratios, predicting higher values than what is observed and thus indicating that an efficient angular momentum transport mechanism should be at work. Here we provide an asteroseismic analysis of a sample of 13 low-luminosity low-mass red giant stars observed by Kepler during its first nominal mission. These targets form a subsample of the 19 red giants studied previously, which not only have a large number of extracted oscillation frequencies, but also unambiguous mode identifications. Aims: We aim to extend the sample of red giants for which internal rotation ratios obtained by theoretical modeling of peak-bagged frequencies are available. We also derive the rotation ratios using different methods, and compare the results of these methods with each other. Methods: We built seismic models using a grid search combined with a Nelder-Mead simplex algorithm and obtained rotation averages employing Bayesian inference and inversion methods. We compared these averages with those obtained using a previously developed model-independent method. Results: We find that the cores of the red giants in this sample are rotating 5 to 10 times faster than their envelopes, which is consistent with earlier results. The rotation rates computed from the different methods show good agreement for some targets, while some discrepancies exist for others.
n-Alkanols potentiate sodium channel inactivation in squid giant axons.
Oxford, G S; Swenson, R P
1979-01-01
The effects of n-octanol and n-decanol on nerve membrane sodium channels were examined in internally perfused, voltage-clamped squid giant axons. Both n-octanol and n-decanol almost completely eliminated the residual sodium conductance at the end of 8-ms voltage steps. In contrast, peak sodium conductance was only partially reduced. This block of peak and residual sodium conductance was very reversible and seen with both internal and external alkanol application. The differential sensitivity of peak and residual conductance to alkanol treatment was eliminated after internal pronase treatment, suggesting that n-octanol and n-decanol enhance the normal inactivation mechanism rather than directly blocking channels in a time-dependent manner. PMID:233577
Non-radial oscillation modes with long lifetimes in giant stars.
De Ridder, Joris; Barban, Caroline; Baudin, Frédéric; Carrier, Fabien; Hatzes, Artie P; Hekker, Saskia; Kallinger, Thomas; Weiss, Werner W; Baglin, Annie; Auvergne, Michel; Samadi, Réza; Barge, Pierre; Deleuil, Magali
2009-05-21
Towards the end of their lives, stars like the Sun greatly expand to become red giant stars. Such evolved stars could provide stringent tests of stellar theory, as many uncertainties of the internal stellar structure accumulate with age. Important examples are convective overshooting and rotational mixing during the central hydrogen-burning phase, which determine the mass of the helium core, but which are not well understood. In principle, analysis of radial and non-radial stellar oscillations can be used to constrain the mass of the helium core. Although all giants are expected to oscillate, it has hitherto been unclear whether non-radial modes are observable at all in red giants, or whether the oscillation modes have a short or a long mode lifetime, which determines the observational precision of the frequencies. Here we report the presence of radial and non-radial oscillations in more than 300 giant stars. For at least some of the giants, the mode lifetimes are of the order of a month. We observe giant stars with equally spaced frequency peaks in the Fourier spectrum of the time series, as well as giants for which the spectrum seems to be more complex. No satisfactory theoretical explanation currently exists for our observations.
Burrell, Caitlin; Zhang, Hemin; Li, Desheng; Wang, Chengdong; Li, Caiwu; Aitken-Palmer, Copper
2017-12-01
The giant panda ( Ailuropoda melanoleuca) is a high-profile threatened species with individuals in captivity worldwide. As a result of advances in captive animal management and veterinary medicine, the ex situ giant panda population is aging, and improved understanding of age-related changes is necessary. Urine and blood samples were collected in April and July 2015 and analyzed for complete blood count, serum biochemistry, and biochemical and microscopic urine analysis for all individuals sampled ( n = 7, 7-16 yr of age) from giant panda housed at the China Research and Conservation Centre for the Giant Panda in Bifengxia, Sichuan Province, China. Hematology and serum biochemistry values were similar to those previously reported for giant panda aged 2-20 yr and to Species360 (formerly International Species Information System) values. Urine was overall dilute (urine specific gravity range: 1.001-1.021), acellular, and acidic (pH range: 6-7). This is the first report of hematologic and serum biochemistry, with associated urinalysis values, in the giant panda aged 7-16 yr.
Layered semi-convection and tides in giant planet interiors. I. Propagation of internal waves
NASA Astrophysics Data System (ADS)
André, Q.; Barker, A. J.; Mathis, S.
2017-09-01
Context. Layered semi-convection is a possible candidate to explain Saturn's luminosity excess and the abnormally large radius of some hot Jupiters. In giant planet interiors, it could lead to the creation of density staircases, which are convective layers separated by thin stably stratified interfaces. These are also observed on Earth in some lakes and in the Arctic Ocean. Aims: We aim to study the propagation of internal waves in a region of layered semi-convection, with the aim to predict energy transport by internal waves incident upon a density staircase. The goal is then to understand the resulting tidal dissipation when these waves are excited by other bodies such as moons in giant planets systems. Methods: We used a local Cartesian analytical model, taking into account the complete Coriolis acceleration at any latitude, thus generalising previous works. We used a model in which stably stratified interfaces are infinitesimally thin, before relaxing this assumption with a second model that assumes a piecewise linear stratification. Results: We find transmission of incident internal waves to be strongly affected by the presence of a density staircase, even if these waves are initially pure inertial waves (which are restored by the Coriolis acceleration). In particular, low-frequency waves of all wavelengths are perfectly transmitted near the critical latitude, defined by θc = sin-1(ω/ 2Ω), where ω is the wave's frequency and Ω is the rotation rate of the planet. Otherwise, short-wavelength waves are only efficiently transmitted if they are resonant with a free mode (interfacial gravity wave or short-wavelength inertial mode) of the staircase. In all other cases, waves are primarily reflected unless their wavelengths are longer than the vertical extent of the entire staircase (not just a single step). Conclusions: We expect incident internal waves to be strongly affected by the presence of a density staircase in a frequency-, latitude- and wavelength-dependent manner. First, this could lead to new criteria to probe the interior of giant planets by seismology; and second, this may have important consequences for tidal dissipation and our understanding of the evolution of giant planet systems.
Contribution of giant fields; Disappearing search for elephants in the U. S
DOE Office of Scientific and Technical Information (OSTI.GOV)
Riva, J.P. Jr.
Oil producing regions have their elephants. These are the giant fields, which, in the U.S., are those that originally contained at least 100 million bbl of recoverable oil. Like top herbivores or carnivores, these giants are relatively scarce, but they also are indicative of the health of a region, an oil producing region. This paper reports that it is difficult to overemphasize the importance of giant oil fields. According to the 1991 edition of the International Petroleum Encyclopedia, of the more than 38,880 domestic oil fields that have been discovered, only 231 are giants (0.6%). Yet, these few fields havemore » produced 53% of domestic oil and still contain 63% of domestic reserves. Taken as a group, the 231 known domestic giant oil fields underlay about 2,310 sq miles (0.06% of U.S. land) and contain the energy equivalent of over 10 billion trees used for firewood or 60 trillion many-days of work.« less
Formation of the giant planets
NASA Technical Reports Server (NTRS)
Lissauer, Jack J.
2006-01-01
The observed properties of giant planets, models of their evolution and observations of protoplanetary disks provide constraints on the formation of gas giant planets. The four largest planets in our Solar System contain considerable quantities of hydrogen and helium, which could not have condensed into solid planetesimals within the protoplanetary disk. All three (transiting) extrasolar giant planets with well determined masses and radii also must contain substantial amounts of these light gases. Jupiter and Saturn are mostly hydrogen and helium, but have larger abundances of heavier elements than does the Sun. Neptune and Uranus are primarily composed of heavier elements. HD 149026 b, which is slightly more massive than is Saturn, appears to have comparable quantities of light gases and heavy elements. HD 209458 b and TrES-1 are primarily hydrogen and helium, but may contain supersolar abundances of heavy elements. Spacecraft flybys and observations of satellite orbits provide estimates of the gravitational moments of the giant planets in our Solar System, which in turn provide information on the internal distribution of matter within Jupiter, Saturn, Uranus and Neptune. Atmospheric thermal structure and heat flow measurements constrain the interior temperatures of planets. Internal processes may cause giant planets to become more compositionally differentiated or alternatively more homogeneous; high-pressure laboratory .experiments provide data useful for modeling these processes. The preponderance of evidence supports the core nucleated gas accretion model. According to this model, giant planets begin their growth by the accumulation of small solid bodies, as do terrestrial planets. However, unlike terrestrial planets, the growing giant planet cores become massive enough that they are able to accumulate substantial amounts of gas before the protoplanetary disk dissipates. The primary questions regarding the core nucleated growth model is under what conditions planets with small cores/total heavy element abundances can accrete gaseous envelopes within the lifetimes of gaseous protoplanetary disks.
Ma, Ben; Lei, Shuo; Qing, Qin; Wen, Yali
2018-05-03
The International Union for Conservation of Nature (IUCN) reduced the threat status of the giant panda from “endangered” to “vulnerable” in September 2016. In this study, we analyzed current practices for giant panda conservation at regional and local environmental scales, based on recent reports of giant panda protection efforts in Sichuan Province, China, combined with the survey results from 927 households within and adjacent to the giant panda reserves in this area. The results showed that household attitudes were very positive regarding giant panda protection efforts. Over the last 10 years, farmers’ dependence on the natural resources provided by giant panda reserves significantly decreased. However, socio-economic development increased resource consumption, and led to climate change, habitat fragmentation, environmental pollution, and other issues that placed increased pressure on giant panda populations. This difference between local and regional scales must be considered when evaluating the IUCN status of giant pandas. While the status of this species has improved in the short-term due to positive local attitudes, large-scale socio-economic development pressure could have long-term negative impacts. Consequently, the IUCN assessment leading to the classification of giant panda as “vulnerable” instead of “endangered”, should not affect its conservation intensity and effort, as such actions could negatively impact population recovery efforts, leading to the extinction of this charismatic species.
Giant geode at the olecranon in the rheumatoid elbow--two case reports.
Nakagawa, Natsuko; Abe, Shuji; Saegusa, Yasuhiro; Kimura, Hiroshi; Imura, Shigeaki; Nishibayashi, Yasuro; Yoshiya, Sinichi
2004-08-01
A single giant geode at the olecranon in a patient with rheumatoid arthritis (RA) is relatively rare, and may cause diagnostic difficulties or cause a spontaneous pathological fracture owing to weakness of the cortical bone associated with osteoporosis. We report two cases of patients presenting with single giant geodes at the olecranon. In one case we performed an open reduction and internal fixation with bone grafting for a pathological fracture due to the geode. In the other case we performed curettage of the geode with bone grafting to prevent a pathological fracture, and a synovectomy of the elbow. We suggest that the presence of a giant geode at the olecranon may necessitate surgical intervention to prevent the occurrence of a spontaneous pathological fracture.
Late-type giants with infrared excess. I. Lithium abundances
NASA Astrophysics Data System (ADS)
Jasniewicz, G.; Parthasarathy, M.; de Laverny, P.; Thévenin, F.
1999-02-01
de la Reza et al. (1997) suggested that all K giants become Li-rich for a short time. During this period the giants are associated with an expanding thin circumstellar shell supposedly triggered by an abrupt internal mixing mechanism resulting in the surface Li enrichment. In order to test this hypothesis twenty nine late-type giants with far-infrared excess from the list of Zuckerman et al. (1995) were observed in the Li-region to study the connection between the circumstellar shells and Li abundance. Eight giants have been found to have log epsilon (Li) > 1.0. In the remaining giants the Li abundance is found to be much lower. HD 219025 is found to be a rapidly rotating (projected rotational velocity of 23 +/-3 km s(-1) ), dusty and Li-rich (log epsilon (Li) = 3.0+/-0.2) K giant. Absolute magnitude derived from the Hipparcos parallax reveals that it is a giant and not a pre-main-sequence star. The evolutionary status of HD 219025 seems to be similar to that of HDE 233517 which is also a rapidly rotating, dusty and Li-rich K giant. The Hipparcos parallaxes of all the well studied Li-rich K giants show that most of them are brighter than the ``clump" giants. Their position in the H-R diagram indicates that they have gone through mixing and the initial abundance of Li is not preserved. There seems to be no correlations between Li abundances, rotational velocities and carbon isotope ratios. The only satisfactory explanation for the overabundance of lithium in these giants is the creation of Li by the extra deep mixing and the associated ``cool bottom processing". Based on observations obtained at the European Southern Observatory, La Silla, Chile, and at the Observatoire de Haute Provence, France.
Fast inactivation of delayed rectifier K conductance in squid giant axon and its cell bodies.
Mathes, C; Rosenthal, J J; Armstrong, G M; Gilly, W F
1997-04-01
Inactivation of delayed rectifier K conductance (gk) was studied in squid giant axons and in the somata of giant fiber lobe (GFL) neurons. Axon measurements were made with an axial wire voltage clamp by pulsing to VK (approximately -10 mV in 50-70 mM external K) for a variable time and then assaying available gK with a strong, brief test pulse. GFL cells were studied with whole-cell patch clamp using the same prepulse procedure as well as with long depolarizations. Under our experimental conditions (12-18 degrees C, 4 mM internal MgATP) a large fraction of gK inactivates within 250 ms at -10 mV in both cell bodies and axons, although inactivation tends to be more complete in cell bodies. Inactivation in both preparations shows two kinetic components. The faster component is more temperature-sensitive and becomes very prominent above 12 degrees C. Contribution of the fast component to inactivation shows a similar voltage dependence to that of gK, suggesting a strong coupling of this inactivation path to the open state. Omission of internal MgATP or application of internal protease reduces the amount of fast inactivation. High external K decreases the amount of rapidly inactivating IK but does not greatly alter inactivation kinetics. Neither external nor internal tetraethylammonium has a marked effect on inactivation kinetics. Squid delayed rectifier K channels in GFL cell bodies and giant axons thus share complex fast inactivation properties that do not closely resemble those associated with either C-type or N-type inactivation of cloned Kvl channels studied in heterologous expression systems.
Fast Inactivation of Delayed Rectifier K Conductance in Squid Giant Axon and Its Cell Bodies
Mathes, Chris; Rosenthal, Joshua J.C.; Armstrong, Clay M.; Gilly, William F.
1997-01-01
Inactivation of delayed rectifier K conductance (gK) was studied in squid giant axons and in the somata of giant fiber lobe (GFL) neurons. Axon measurements were made with an axial wire voltage clamp by pulsing to VK (∼−10 mV in 50–70 mM external K) for a variable time and then assaying available gK with a strong, brief test pulse. GFL cells were studied with whole-cell patch clamp using the same prepulse procedure as well as with long depolarizations. Under our experimental conditions (12–18°C, 4 mM internal MgATP) a large fraction of gK inactivates within 250 ms at −10 mV in both cell bodies and axons, although inactivation tends to be more complete in cell bodies. Inactivation in both preparations shows two kinetic components. The faster component is more temperature-sensitive and becomes very prominent above 12°C. Contribution of the fast component to inactivation shows a similar voltage dependence to that of gK, suggesting a strong coupling of this inactivation path to the open state. Omission of internal MgATP or application of internal protease reduces the amount of fast inactivation. High external K decreases the amount of rapidly inactivating IK but does not greatly alter inactivation kinetics. Neither external nor internal tetraethylammonium has a marked effect on inactivation kinetics. Squid delayed rectifier K channels in GFL cell bodies and giant axons thus share complex fast inactivation properties that do not closely resemble those associated with either C-type or N-type inactivation of cloned Kv1 channels studied in heterologous expression systems. PMID:9101403
OCEANUS: A high science return Uranus orbiter with a low-cost instrument suite
NASA Astrophysics Data System (ADS)
Elder, C. M.; Bramson, A. M.; Blum, L. W.; Chilton, H. T.; Chopra, A.; Chu, C.; Das, A.; Davis, A. B.; Delgado, A.; Fulton, J.; Jozwiak, L. M.; Khayat, A.; Landis, M. E.; Molaro, J. L.; Slipski, M.; Valencia, S.; Watkins, J.; Young, C. L.; Budney, C. J.; Mitchell, K. L.
2018-07-01
Ice-giant-sized planets are the most common type of observed exoplanet, yet the two ice giants in our own solar system (Uranus and Neptune) are the least explored class of planet, having only been observed through ground-based observations and a single flyby each by Voyager 2 approximately 30 years ago. These single flybys were unable to characterize the spatial and temporal variability in ice giant magnetospheres, some of the most odd and intriguing magnetospheres in the solar system. They also offered only limited constraints on the internal structure of ice giants; understanding the internal structure of a planet is important for understanding its formation and evolution. The most recent planetary science Decadal Survey by the U.S. National Academy of Sciences, "Vision and Voyages for Planetary Science in the Decade 2013-2022," identified the ice giant Uranus as the third highest priority for a Flagship mission in the decade 2013-2022. However, in the event that NASA or another space agency is unable to fly a Flagship-class mission to an ice giant in the next decade, this paper presents a mission concept for a focused, lower cost Uranus orbiter called OCEANUS (Origins and Composition of the Exoplanet Analog Uranus System). OCEANUS would increase our understanding of the interior structure of Uranus, its magnetosphere, and how its magnetic field is generated. These goals could be achieved with just a magnetometer and the spacecraft's radio system. This study shows that several of the objectives outlined by the Decadal Survey, including one of the two identified as highest priority, are within reach for a New-Frontiers-class mission.
Hot-start Giant Planets Form with Radiative Interiors
DOE Office of Scientific and Technical Information (OSTI.GOV)
Berardo, David; Cumming, Andrew, E-mail: david.berardo@mcgill.ca, E-mail: andrew.cumming@mcgill.ca
In the hot-start core accretion formation model for gas giants, the interior of a planet is usually assumed to be fully convective. By calculating the detailed internal evolution of a planet assuming hot-start outer boundary conditions, we show that such a planet will in fact form with a radially increasing internal entropy profile, so that its interior will be radiative instead of convective. For a hot outer boundary, there is a minimum value for the entropy of the internal adiabat S {sub min} below which the accreting envelope does not match smoothly onto the interior, but instead deposits high entropymore » material onto the growing interior. One implication of this would be to at least temporarily halt the mixing of heavy elements within the planet, which are deposited by planetesimals accreted during formation. The compositional gradient this would impose could subsequently disrupt convection during post-accretion cooling, which would alter the observed cooling curve of the planet. However, even with a homogeneous composition, for which convection develops as the planet cools, the difference in cooling timescale will change the inferred mass of directly imaged gas giants.« less
Modeling activity patterns of wildlife using time-series analysis.
Zhang, Jindong; Hull, Vanessa; Ouyang, Zhiyun; He, Liang; Connor, Thomas; Yang, Hongbo; Huang, Jinyan; Zhou, Shiqiang; Zhang, Zejun; Zhou, Caiquan; Zhang, Hemin; Liu, Jianguo
2017-04-01
The study of wildlife activity patterns is an effective approach to understanding fundamental ecological and evolutionary processes. However, traditional statistical approaches used to conduct quantitative analysis have thus far had limited success in revealing underlying mechanisms driving activity patterns. Here, we combine wavelet analysis, a type of frequency-based time-series analysis, with high-resolution activity data from accelerometers embedded in GPS collars to explore the effects of internal states (e.g., pregnancy) and external factors (e.g., seasonal dynamics of resources and weather) on activity patterns of the endangered giant panda ( Ailuropoda melanoleuca ). Giant pandas exhibited higher frequency cycles during the winter when resources (e.g., water and forage) were relatively poor, as well as during spring, which includes the giant panda's mating season. During the summer and autumn when resources were abundant, pandas exhibited a regular activity pattern with activity peaks every 24 hr. A pregnant individual showed distinct differences in her activity pattern from other giant pandas for several months following parturition. These results indicate that animals adjust activity cycles to adapt to seasonal variation of the resources and unique physiological periods. Wavelet coherency analysis also verified the synchronization of giant panda activity level with air temperature and solar radiation at the 24-hr band. Our study also shows that wavelet analysis is an effective tool for analyzing high-resolution activity pattern data and its relationship to internal and external states, an approach that has the potential to inform wildlife conservation and management across species.
Coordinated observations of interacting peculiar red giant binaries, 2
NASA Technical Reports Server (NTRS)
Ake, T.
1995-01-01
IUE and H alpha observations continued on a two-year program to monitor the UV variability of three interacting peculiar red giant (PRG) binaries, HD 59643 (C6,s), HD 35155 (S3/2), and HR 1105 (S3.5/2.5). All of these systems were suspected to involve accretion of material from the PRG to a white-dwarf secondary, based mainly on previous IUE investigations. They were primary candidates from earlier surveys of PRG's to test the hypothesis that the Tc-poor PRG's are formed as a result of mass transfer from a secondary component rather than from internal thermal pulsing while on the asymptotic red giant branch.
Coordinated observations of interacting peculiar red giant binaries, 1
NASA Technical Reports Server (NTRS)
Ake, T.
1995-01-01
IUE Observations were begun for a two-year program to monitor the UV variability of three interacting peculiar red giant (PRG) binaries, HD 59643 (C6,s) HD 35155 (S3/2), and HR 1105 (S3.5/2.5). All of these systems were suspected to involve accretion of material from the PRG to a white-dwarf secondary, based mainly on previous IUE investigations. From our earlier surveys of PRG's, they were primary candidates to test the hypothesis that Tc-poor PRG's are formed as a result of mass transfer from a secondary component rather than from internal thermal pulsing while on the asymptotic red giant branch.
Mohri, Masanao; Ichinose, Toshiya; Uchiyama, Naoyuki; Misaki, Kouichi; Nambu, Iku; Takabatake, Yasushi; Nakada, Mitsutoshi
2018-04-21
Hyperperfusion syndrome associated with aneurysm surgery is rare. The occurrence of the syndrome after trapping with high-flow bypass has not been described previously. Herein, we present a case of the syndrome occurring after trapping with high-flow bypass of an unruptured giant paraclinoid internal carotid artery (ICA) aneurysm. The patient was a 68-year-old woman with progressive loss of vision in her left eye. After a diagnosis of a left giant ICA aneurysm, she underwent successful trapping with high-flow bypass. No new neurological deficits were observed after surgery. Computed tomography (CT) on the same day and magnetic resonance imaging (MRI) on the next day revealed no hemorrhage or infarction. The patient had a headache and transit motor aphasia on postoperative day (POD) 8. Arterial spin-labeling magnetic resonance perfusion image on the same day and single photon emission CT scan on POD 10 demonstrated hyperperfusion in the left cerebral cortex. The symptoms gradually improved over a week and she had no new neurological deficits when discharged from hospital. This report suggests that, although rare, hyperperfusion syndrome after trapping with high-flow bypass should be considered in giant aneurysmal patients if they present with headache and neurological deficits in a delayed period. Copyright © 2018. Published by Elsevier Inc.
Pahl, Felix Hendrik; de Oliveira, Matheus Fernandes; Beer-Furlan, André Luiz; Rotta, José Marcus
2016-01-01
Background: Internal carotid artery bifurcation (ICAb) aneurysms account for about 2–15% of all intracranial aneurysms. In giant and complex cases, treatment may be difficult and dangerous, once some aneurysms have wide neck and anterior cerebral artery (ACA) and middle cerebral artery (MCA) may arise from the aneurysm itself. Clip reconstruction may be difficult in such cases. Whenever possible, the occlusion of ACA transform the bifurcation in a single artery reconstruction (ICA to MCA), much easier than a bifurcation reconstruction. Methods: In patients with giant and complex ICAb aneurysms, we propose routine preoperative angiography with anatomical evaluation of anterior communicating artery (ACoA) patency during cervical common carotid compression with concomitant contralateral carotid artery injection. This allowed visualization of the expected reversal of flow in the A1 segment–ACoA complex. When test is positive, we can perform ipsilateral ACA (A1 segment) clip occlusion and flow modification of the ACA-ACoA complex transforming a three vessel (ICA, ACA, and MCA) reconstruction into a two vessel (ICA and MCA) reconstruction. Results: Two patients were treated, with 100% of occlusion and good outcome. Conclusions: Surgical treatment of giant and complex ICAb may be achieved with acceptable morbidity. PMID:27313968
IMPLICATIONS OF RAPID CORE ROTATION IN RED GIANTS FOR INTERNAL ANGULAR MOMENTUM TRANSPORT IN STARS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tayar, Jamie; Pinsonneault, Marc H., E-mail: tayar.1@osu.edu
2013-09-20
Core rotation rates have been measured for red giant stars using asteroseismology. These data, along with helioseismic measurements and open cluster spin-down studies, provide powerful clues about the nature and timescale for internal angular momentum transport in stars. We focus on two cases: the metal-poor red giant KIC 7341231 ({sup O}tto{sup )} and intermediate-mass core helium burning stars. For both, we examine limiting case studies for angular momentum coupling between cores and envelopes under the assumption of rigid rotation on the main sequence. We discuss the expected pattern of core rotation as a function of mass and radius. In themore » case of Otto, strong post-main-sequence coupling is ruled out and the measured core rotation rate is in the range of 23-33 times the surface value expected from standard spin-down models. The minimum coupling timescale (0.17-0.45 Gyr) is significantly longer than that inferred for young open cluster stars. This implies ineffective internal angular momentum transport in early first ascent giants. By contrast, the core rotation rates of evolved secondary clump stars are found to be consistent with strong coupling given their rapid main-sequence rotation. An extrapolation to the white dwarf regime predicts rotation periods between 330 and 0.0052 days, depending on mass and decoupling time. We identify two key ingredients that explain these features: the presence of a convective core and inefficient angular momentum transport in the presence of larger mean molecular weight gradients. Observational tests that can disentangle these effects are discussed.« less
Sodium movements in perfused squid giant axons. Passive fluxes.
Rojas, E; Canessa-Fischer, M
1968-08-01
Sodium movements in internally perfused giant axons from the squid Dosidicus gigas were studied with varying internal sodium concentrations and with fluoride as the internal anion. It was found that as the internal concentration of sodium was increased from 2 to 200 mM the resting sodium efflux increased from 0.09 to 34.0 pmoles/cm(2)sec and the average resting sodium influx increased from 42.9 to 64.5 pmoles/cm(2)sec but this last change was not statistically significant. When perfusing with a mixture of 500 mM K glutamate and 100 mM Na glutamate the resting efflux was 10 +/- 3 pmoles/cm(2)sec and 41 +/- 10 pmoles/cm(2)sec for sodium influx. Increasing the internal sodium concentration also increased both the extra influx and the extra efflux of sodium due to impulse propagation. At any given internal sodium concentration the net extra influx was about 5 pmoles/cm(2)impulse. This finding supports the notion that the inward current generated in a propagated action potential can be completely accounted for by movements of sodium.
Sodium Movements in Perfused Squid Giant Axons
Rojas, Eduardo; Canessa-Fischer, Mitzy
1968-01-01
Sodium movements in internally perfused giant axons from the squid Dosidicus gigas were studied with varying internal sodium concentrations and with fluoride as the internal anion. It was found that as the internal concentration of sodium was increased from 2 to 200 mM the resting sodium efflux increased from 0.09 to 34.0 pmoles/cm2sec and the average resting sodium influx increased from 42.9 to 64.5 pmoles/cm2sec but this last change was not statistically significant. When perfusing with a mixture of 500 mM K glutamate and 100 mM Na glutamate the resting efflux was 10 ± 3 pmoles/cm2sec and 41 ± 10 pmoles/cm2sec for sodium influx. Increasing the internal sodium concentration also increased both the extra influx and the extra efflux of sodium due to impulse propagation. At any given internal sodium concentration the net extra influx was about 5 pmoles/cm2impulse. This finding supports the notion that the inward current generated in a propagated action potential can be completely accounted for by movements of sodium. PMID:5672003
[Intestinal fungal diversity of sub-adult giant panda].
Ai, Shengquan; Zhong, Zhijun; Peng, Guangneng; Wang, Chengdong; Luo, Yongjiu; He, Tingmei; Gu, Wuyang; Li, Caiwu; Li, Gangshi; Wu, Honglin; Liu, Xuehan; Xia, Yu; Liu, Yanhong; Zhou, Xiaoxiao
2014-11-04
The fungi diversity in the guts of five sub-adult giant pandas was analyzed. We analyzed the fungal internal transcribed spacer sequences (ITS) using restriction fragment length polymorphism (RFLP). ITS regions were amplified with fungal universal primers to construct ITS clone libraries. The fingerprints were analyzed by restriction fragment length polymorphism using the Hha I and Hae III enzymes. The cloned PCR products were analyzed by sequencing and diversities were demonstrated by phylogenetic tree. The gut fungi of 5 sub-adult giant pandas were mainly composed of Ascomycota (average of 46.24%), Basidiomycota ( average of 15.79%), unclassified (average of 29.14%), uncultured fungus (average of 8.83% ). Ascomycota was mainly composed of Saccharomycetes (average of 63.74%) and Dothideomycetes ( average of 35.91%); Basidiomycota was mainly composed of Tremellomycetes (average of 65.80%) and Microbotryomycetes (average of 33.15%). Four classes were mainly composed of Candida and Debaryomyces; Pleosporales and Myriangium; Cystofilobasidium and Trichosporon; Leucosporidium, and Leucosporidiella, whereas the proportions were different for each sample. Fungal flora existing in the intestines of sub-adult giant pandas expand our knowledge on the structure of the giant panda gut microbes and also help us to further study whether fungal flora can help giant pandas digest high-fiber foods.
Wu, Chen; Xu, Bai-Nan; Sun, Zheng-Hui; Wang, Fu-Yu; Liu, Lei; Zhang, Xiao-Jun; Zhou, Ding-Biao
2012-01-01
Unclippable fusiform basilar trunk aneurysm is a formidable condition for surgical treatment. The aim of this study was to establish a computational model and to investigate the hemodynamic characteristics in a fusiform basilar trunk aneurysm. The three-dimensional digital model of a fusiform basilar trunk aneurysm was constructed using MIMICS, ANSYS and CFX software. Different hemodynamic modalities and border conditions were assigned to the model. Thirty points were selected randomly on the wall and within the aneurysm. Wall total pressure (WTP), wall shear stress (WSS), and blood flow velocity of each point were calculated and hemodynamic status was compared between different modalities. The quantitative average values of the 30 points on the wall and within the aneurysm were obtained by computational calculation point by point. The velocity and WSS in modalities A and B were different from those of the remaining 5 modalities; and the WTP in modalities A, E and F were higher than those of the remaining 4 modalities. The digital model of a fusiform basilar artery aneurysm is feasible and reliable. This model could provide some important information to clinical treatment options.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Smith, Verne V.; Cunha, Katia; Shetrone, Matthew D.
2013-03-01
High-resolution H-band spectra of five bright field K, M, and MS giants, obtained from the archives of the Kitt Peak National Observatory Fourier transform spectrometer, are analyzed to determine chemical abundances of 16 elements. The abundances were derived via spectrum synthesis using the detailed linelist prepared for the Sloan Digital Sky Survey III Apache Point Galactic Evolution Experiment (APOGEE), which is a high-resolution near-infrared spectroscopic survey to derive detailed chemical abundance distributions and precise radial velocities for 100,000 red giants sampling all Galactic stellar populations. The red giant sample studied here was chosen to probe which chemical elements can bemore » derived reliably from the H-band APOGEE spectral region. These red giants consist of two K-giants ({alpha} Boo and {mu} Leo), two M-giants ({beta} And and {delta} Oph), and one thermally pulsing asymptotic giant branch (TP-AGB) star of spectral type MS (HD 199799). Measured chemical abundances include the cosmochemically important isotopes {sup 12}C, {sup 13}C, {sup 14}N, and {sup 16}O, along with Mg, Al, Si, K, Ca, Ti, V, Cr, Mn, Fe, Co, Ni, and Cu. The K and M giants exhibit the abundance signature of the first dredge-up of CN-cycle material, while the TP-AGB star shows clear evidence of the addition of {sup 12}C synthesized during {sup 4}He-burning thermal pulses and subsequent third dredge-up. A comparison of the abundances derived here with published values for these stars reveals consistent results to {approx}0.1 dex. The APOGEE spectral region and linelist is thus well suited for probing both Galactic chemical evolution, as well as internal nucleosynthesis and mixing in populations of red giants via high-resolution spectroscopy.« less
Mismatch between the eye and the optic lobe in the giant squid.
Liu, Yung-Chieh; Liu, Tsung-Han; Yu, Chun-Chieh; Su, Chia-Hao; Chiao, Chuan-Chin
2017-07-01
Giant squids ( Architeuthis ) are a legendary species among the cephalopods. They live in the deep sea and are well known for their enormous body and giant eyes. It has been suggested that their giant eyes are not adapted for the detection of either mates or prey at distance, but rather are best suited for monitoring very large predators, such as sperm whales, at distances exceeding 120 m and at a depth below 600 m (Nilsson et al. 2012 Curr. Biol. 22 , 683-688. (doi:10.1016/j.cub.2012.02.031)). However, it is not clear how the brain of giant squids processes visual information. In this study, the optic lobe of a giant squid ( Architeuthis dux , male, mantle length 89 cm), which was caught by local fishermen off the northeastern coast of Taiwan, was scanned using high-resolution magnetic resonance imaging in order to examine its internal structure. It was evident that the volume ratio of the optic lobe to the eye in the giant squid is much smaller than that in the oval squid ( Sepioteuthis lessoniana ) and the cuttlefish ( Sepia pharaonis ). Furthermore, the cell density in the cortex of the optic lobe is significantly higher in the giant squid than in oval squids and cuttlefish, with the relative thickness of the cortex being much larger in Architeuthis optic lobe than in cuttlefish. This indicates that the relative size of the medulla of the optic lobe in the giant squid is disproportionally smaller compared with these two cephalopod species. This morphological study of the giant squid brain, though limited only to the optic lobe, provides the first evidence to support that the optic lobe cortex, the visual information processing area in cephalopods, is well developed in the giant squid. In comparison, the optic lobe medulla, the visuomotor integration centre in cephalopods, is much less developed in the giant squid than other species. This finding suggests that, despite the giant eye and a full-fledged cortex within the optic lobe, the brain of giant squids has not evolved proportionally in terms of performing complex tasks compared with shallow-water cephalopod species.
Giant dielectric constant in CaCu3Ti4O12 nanoceramics
NASA Astrophysics Data System (ADS)
Ahmad, Mohamad M.
2013-06-01
Nanoceramics of CaCu3Ti4O12 (CCTO) were synthesized by mechanosynthesis and spark plasma sintering with grain size of 150-200 nm. Giant dielectric constant properties are observed in the CCTO nanoceramics due to internal barrier layer capacitance (IBLC) effects. Impedance spectroscopy data suggest that the presence of resistive grain boundaries in addition to resistive domain boundaries is the origin of the IBLCs in CCTO nanoceramics.
The core mass-radius relation for giants - A new test of stellar evolution theory
NASA Technical Reports Server (NTRS)
Joss, P. C.; Rappaport, S.; Lewis, W.
1987-01-01
It is demonstrated here that the measurable properties of systems containing degenerate dwarfs can be used as a direct test of the core mass-radius relation for moderate-mass giants if the final stages of the loss of the envelope of the progenitor giant occurred via stable critical lobe overflow. This relation directly probes the internal structure of stars at a relatively advanced evolutionary state and is only modestly influenced by adjustable parameters. The measured properties of six binary systems, including such diverse systems as Sirius and Procyon and two millisecond pulsars, are utilized to derive constraints on the empirical core mass-radius relation, and the constraints are compared to the theoretical relation. The possibility that the final stages of envelope ejection of the giant progenitor of Sirius B occurred via critical lobe overflow in historical times is considered.
A NEW TWIST IN THE EVOLUTION OF LOW-MASS STARS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Denissenkov, Pavel A., E-mail: pavelden@uvic.ca
2012-07-01
We show that the evolutionary track of a low-mass red giant should make an extended zigzag on the Hertzsprung-Russel diagram just after the bump luminosity if fast internal rotation and enhanced extra mixing in the radiative zone bring the temperature gradient close to the adiabatic one. This can explain both the location and peculiar surface chemical composition of Li-rich K giants studied by Kumar et al. We also discuss a striking resemblance between the photometric and composition peculiarities of these stars and giant components of RS CVn binaries. We demonstrate that the observationally constrained values of the temperature gradient inmore » the Li-rich K giants agree with the required rate of extra mixing only if the turbulence that is believed to be responsible for this extra mixing is highly anisotropic, with its associated transport coefficients in the horizontal direction strongly dominating over those in the vertical direction.« less
Chronic Traumatic Giant Macular Hole Repair with Autologous Platelets.
Coca, Mircea; Makkouk, Fuad; Picciani, Renata; Godley, Bernard; Elkeeb, Ahmed
2017-01-05
We report on the closure of a chronic posttraumatic giant macular hole. The patient presented with decreased vision in the left eye following blunt trauma 20 years prior. His dilated fundus examination revealed a 3000 um base-diameter full thickness macular hole. Surgical repair was performed with pars plana vitrectomy (PPV), internal limiting membrane peeling and autologous platelet concentrate (APC) injected over the macular hole. At one month follow-up, the macular hole had closed on exam and optical coherence tomography (OCT), and the patient reported subjective visual improvement. To our knowledge, this report presents the first case of a chronic giant macular hole successfully closed after undergoing surgery with adjuvant platelets therapy.
Far-ultraviolet fluorescence of carbon monoxide in the red giant Arcturus
NASA Technical Reports Server (NTRS)
Ayres, T. R.; Moos, H. W.; Linsky, J. L.
1981-01-01
Evidence is presented that many of the weak features observed with International Ultraviolet Explorer (IUE) in the far-ultraviolet (1150-2000 A) spectrum of the archetype red giant Arcturus (K2 III) are A-X fourth positive bands of carbon monoxide excited by chromospheric emissions of O I, C I, and H I. The appearance of fluorescent CO bands near the wavelength of commonly used indicators of high-temperature (T greater than 20,000 K) plasma, such as C II at wavelength 1335 and C IV at wavelength 1548, introduces a serious ambiguity in diagnosing the presence of hot material in the outer atmospheres of the cool giants by means of low-dispersion IUE spectra.
Ultraviolet spectral variations of symbiotic nova PU Vul during and after second eclipse
NASA Astrophysics Data System (ADS)
Sanad, M. R.
2016-12-01
I have analyzed spectral data of the symbiotic nova PU Vul observed with the International Ultraviolet Explorer (IUE) during the period 1993-1996. The study concentrated on the two sources of nebular emitting regions, the first is a nebula around the white dwarf partially eclipsed by a cool giant star and the second is a very extended nebular region not affected by the eclipse of the giant star. I concentrated on the N IV] 1486 Å and C IV 1550 Å emission lines produced in the first region and N III] 1750 Å and C III] 1909 Å emission lines produced in the second region very far from the giant star.
Giant melanocytic nevus with malignant melanoma: a rare disorder in a black African child.
Katibi, Oludolapo Sherifat; Ogunbiyi, Adebola; Brown, Biobele Jotham; Adeyemi, Oyedeji Oladele
2014-10-01
Giant congenital melanocytic nevus (GCMN) is rare in babies of African descent. Unfortunately, it has an increased potential for malignant transformation. A 3-year-old female child presented with a 6-month history of multiple nodules on an existing giant congenital melanocytic nevus and swelling in the right axilla of four weeks duration. Skin biopsy of the nodular skin lesions was in keeping with a metastatic malignant melanoma (Clark stage 4). She completed a full course of chemotherapy but subsequently died four months after presentation. Patients with large GCMN should be counseled and followed up appropriately to improve and prolong life. © 2014 The International Society of Dermatology.
Chronic Traumatic Giant Macular Hole Repair with Autologous Platelets
Makkouk, Fuad; Picciani, Renata; Godley, Bernard; Elkeeb, Ahmed
2017-01-01
We report on the closure of a chronic posttraumatic giant macular hole. The patient presented with decreased vision in the left eye following blunt trauma 20 years prior. His dilated fundus examination revealed a 3000 um base-diameter full thickness macular hole. Surgical repair was performed with pars plana vitrectomy (PPV), internal limiting membrane peeling and autologous platelet concentrate (APC) injected over the macular hole. At one month follow-up, the macular hole had closed on exam and optical coherence tomography (OCT), and the patient reported subjective visual improvement. To our knowledge, this report presents the first case of a chronic giant macular hole successfully closed after undergoing surgery with adjuvant platelets therapy. PMID:28168133
Energetic Aspects of Non-Radial Solar-Like Oscillations in Red Giants
NASA Astrophysics Data System (ADS)
Dupret, Marc-Antoine; Belkacem, Kévin
The non-radial oscillations discovered by CoRoT (see e.g. de Ridder et al. (2009)) and by Kepler(see e.g. Bedding et al. (2010)) in thousands of red giants constitute a wonderful mine of information to determine their global characteristics and probe their internal structure. A. Miglio and J. Montalbán have presented in detail in this conference the seismic structure of red giants, the information hold by their oscillation frequencies, and how it can be used. An adiabatic analysis of the oscillations was sufficient at this level as the frequencies are mainly determined by the deep layers were the oscillatons are quasi-adiabatic. We consider here energetic aspects of non-radial oscillations in red-giants. Non-adiabatic models of solar-like oscillations are required to determine the theoretical amplitude and lifetimes of the modes. These parameters allow us to determine how power spectra are expected to look like, depending on the structure of the red giant. Comparison with the observed measures gives thus additional constraints on the models.
Giant panda conservation science: how far we have come.
Swaisgood, Ronald R; Wei, Fuwen; Wildt, David E; Kouba, Andrew J; Zhang, Zejun
2010-04-23
The giant panda is a conservation icon, but science has been slow to take up its cause in earnest. In the past decade, researchers have been making up for lost time, as reflected in the flurry of activity reported at the symposium Conservation Science for Giant Pandas and Their Habitat at the 2009 International Congress for Conservation Biology (ICCB) in Beijing. In reports addressing topics ranging from spatial ecology to molecular censusing, from habitat recovery in newly established reserves to earthquake-induced habitat loss, from new insights into factors limiting carrying capacity to the uncertain effects of climate change, this symposium displayed the vibrant and blossoming application of science to giant panda conservation. Collectively, we find that we have come a long way, but we also reach an all-too-familiar conclusion: the more we know, the more challenges are revealed. While many earlier findings are supported, many of our assumptions are debatable. Here we discuss recent advancements in conservation science for giant pandas and suggest that the way forward is more direct application of emerging science to management and policy.
Scientometrics of zoonoses transmitted by the giant African snail Achatina fulica Bowdich, 1822.
Pavanelli, Gilberto Cezar; Yamaguchi, Mirian Ueda; Calaça, Elaine Alves; Oda, Fabrício Hiroiuki
2017-04-13
The dissemination of the giant African snail Achatina fulica in several countries has triggered a great number of studies on the mollusk, including those on zoonoses related to health in humans. The current research is a scientific survey on articles published in four databases, namely, PubMed, Bireme, Scielo and Lilacs. Results indicate that Brazil has a prominent position in international scientific production on this subject, with focus on Angiostrongylus cantonensis occurrences.
Hasegawa, Hirotaka; Inoue, Tomohiro; Tamura, Akira; Saito, Isamu
2016-10-01
Direct clipping of giant partially thrombosed intracranial internal carotid artery (ICA) aneurysms is challenging, especially when important perforating arteries are involved. Proximal occlusion with bypass represents a possible alternative approach. An 80-year-old female presented with worsening visual acuity and severe headache caused by partially thrombosed giant (38 mm in diameter) aneurysms of the right ICA, suggestive of impending rupture. Direct clipping in conjunction with temporary occlusion of the lesion involving the anterior choroidal artery (AChA) was considered too risky. Thus, we sequestrated the ipsilateral ICA flow into a low-flow and a high-flow system using two external carotid artery (ECA)-ICA bypasses and one in situ bypass with cervical ICA ligation. As a result, the low-flow system by the superficial temporal artery-middle cerebral artery (MCA) bypass perfused mainly the proximal MCA lesions and aneurysm, whereas the high-flow system by ECA-radial artery-M2 bypass exclusively supplied the residual distal MCA area. This tailored flow sequestration successfully interrupted intra-aneurysmal flow and accelerated near-complete thrombosis of the aneurysm while preserving the AChA and avoiding any significant neurological deterioration. We conclude that this method is effective for the management of giant partially thrombosed aneurysms of the ICA, especially when direct clipping is difficult.
Ikedo, Taichi; Nakamura, Kazuhito; Sano, Noritaka; Nagata, Manabu; Okada, Yumiko; Kawakami, Taichiro; Murata, Takaho
2017-10-01
Deformed osseous structures have been reported as rare causes of extracranial internal carotid artery (ICA) dissection, including the styloid process and the hyoid bone. Here, the authors describe the first known case of symptomatic ICA dissection caused by a giant osteophyte due to atlantoaxial osteoarthritis. The left ICA was fixed at the skull base and at the ICA portion compressed by the osteophyte, and it was highly stretched and injured between the two portions during neck rotation. The patient was successfully treated with ligation of the affected ICA following balloon test occlusion. Atlantoaxial osteoarthritis should be considered in the differential diagnosis of ICA dissection in patients with a severely deformed cervical spine.
The Lushan earthquake and the giant panda: impacts and conservation.
Zhang, Zejun; Yuan, Shibin; Qi, Dunwu; Zhang, Mingchun
2014-06-01
Earthquakes not only result in a great loss of human life and property, but also have profound effects on the Earth's biodiversity. The Lushan earthquake occurred on 20 Apr 2013, with a magnitude of 7.0 and an intensity of 9.0 degrees. A distance of 17.0 km from its epicenter to the nearest distribution site of giant pandas recorded in the Third National Survey was determined. Making use of research on the Wenchuan earthquake (with a magnitude of 8.0), which occurred approximately 5 years ago, we briefly analyze the impacts of the Lushan earthquake on giant pandas and their habitat. An earthquake may interrupt ongoing behaviors of giant pandas and may also cause injury or death. In addition, an earthquake can damage conservation facilities for pandas, and result in further habitat fragmentation and degradation. However, from a historical point of view, the impacts of human activities on giant pandas and their habitat may, in fact, far outweigh those of natural disasters such as earthquakes. Measures taken to promote habitat restoration and conservation network reconstruction in earthquake-affected areas should be based on requirements of giant pandas, not those of humans. © 2013 International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and Wiley Publishing Asia Pty Ltd.
Perspectives on the World: International Education Instructional Units.
ERIC Educational Resources Information Center
Kallner, Pam; And Others
This publication is a compilation of lessons and unit plans developed by teachers of the Bexley, Ohio City School District through an international education program. Sample lesson plans include: "Giant Pandas from China" (Grade 1); "Haiku Writing" (Grade 4); and "Treasures--Ancient Civilizations of Ohio" (Grade 7).…
Meridional circulation and CNO anomalies in red giant stars
NASA Technical Reports Server (NTRS)
Sweigart, A. V.; Mengel, J. G.
1979-01-01
The possibility is investigated that meridional circulation driven by internal rotation might lead to the mixing of CNO-processed material from the vicinity of the hydrogen shell into the envelope of a red giant star. This theory of meridional mixing is found to be generally consistent with available data and to be capable of explaining a number of observational results without invoking a radical departure from the standard physics of stellar interiors. It is suggested that meridional circulation must be a normal characteristic of a rotating star and that meridional mixing provides a reasonable framework for understanding many of the CNO anomalies exhibited by weak-G-band and CN-strong stars as well as the low C-12/C-13 ratios measured among field red giants.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hekker, S.; Debosscher, J.; De Ridder, J.
2010-04-20
Oscillating stars in binary systems are among the most interesting stellar laboratories, as these can provide information on the stellar parameters and stellar internal structures. Here we present a red giant with solar-like oscillations in an eclipsing binary observed with the NASA Kepler satellite. We compute stellar parameters of the red giant from spectra and the asteroseismic mass and radius from the oscillations. Although only one eclipse has been observed so far, we can already determine that the secondary is a main-sequence F star in an eccentric orbit with a semi-major axis larger than 0.5 AU and orbital period longermore » than 75 days.« less
The "DREAM" IODP project to drill the Mediterranean Salt Giant on the Balearic Promontory
NASA Astrophysics Data System (ADS)
Lofi, Johanna; Camerlenghi, Angelo; Aloisi, Giovanni; Maillard, Agnès; Garcia-Castellanos, Daniel; Huebscher, Christian; Kuroda, Junichiro
2017-04-01
Salt giants preserving kilometer-thick evaporite layers are the sedimentary expression of extreme environmental events of global relevance. Despite their global occurrence and general importance on Earth, there is currently no complete stratigraphic record through an un-deformed salt giant of marine origin. Similarly, there is a significant lack of knowledge about the factors controlling salt giants deposition, their early evolution, the impact they exert on the isostatic response of continental margins and on sub-salt formations, and the unprecedented deep biosphere they may harbor. The Mediterranean Messinian salt giant, which formed 5.5 Myrs ago, is one of the youngest salt giant on Earth and is currently lying below the Plio-Quaternary cover in a relatively un-deformed state close to its original depositional configuration. This salt giant is thus accessible by drilling and forms an ideal case study that could be used as a reference for older salt giants. However, since its discovery in 1970 during the DSDP Leg XIII, and despite 40 years or multi-disciplinary researches, this salt giant is still not fully understood and remains one of the longest-living controversies in Earth Science. In this context, the IODP DREAM project aims at exploring the Mediterranean salt giant by drilling with the JOIDES Resolution a transect of 4 sites on the southern margin of the Balearic promontory (Western Mediterranean). We identified this area as likely the only place in the Mediterranean where we could implement a shallow-to-deep transect of non-riser drilling sites. Due to the geological history and pre-structuration of the Promontory, MSC deposits are found preserved in a series of sedimentary basins lying at different water depths between the present-day coastline and the deep central salt basins. DREAM thus offers a unique opportunity to sample several hundred of meters of material forming the Mediterranean salt giant in varied water depths. This unique sedimentary record should allow testing 1) the contradictory emplacement models that explain its genesis and 2) the presence of halophilic micro-organisms it may host/feed. DREAM is a part of a bigger Multi-phase IODP Drilling Project entitled "Uncovering a Salt Giant" (857-MDP, coord. A. Camerlenghi) born out of a series of workshops and international initiatives carried out since 2014. The DREAM pre-proposal P857B has been accepted by the IODP Science Evaluation Panel in January 2016. The full-proposal will be submitted after the acquisition of complementary Site Survey Data in 2017. The DREAM project is performed in close link with various international initiatives including the COST Action CA15103 and ANR Project MEDSALT (Camerlenghi et al., this congress) and the IMMAGE ICDP-IODP amphibious proposal (Flecker et al., this congress). DREAM co-proponents: J. Anton, M.A. Bassetti, D. Birgel, R. Bourillot, A. Caruso, H. Daigle, G. DeLange, F. Dela Pierre, R. Flecker, V. Gaullier, D. Hodell, F. Jimenez-Espejo, W. Krijgsman, L. Lourens, S. Lugli, V. Manzi, T. McGenity, J. McKenzie, P. Meijer, H. Moreno, A. Moscariello, P. Munch, N. Ohkouchi, J. Peckmann, P. Pezard, J. Poort, M. Roveri, F. Sierro, K. Takai, T. Treude.
Scientometrics of zoonoses transmitted by the giant African snail Achatina fulica Bowdich, 1822
Pavanelli, Gilberto Cezar; Yamaguchi, Mirian Ueda; Calaça, Elaine Alves; Oda, Fabrício Hiroiuki
2017-01-01
ABSTRACT The dissemination of the giant African snail Achatina fulica in several countries has triggered a great number of studies on the mollusk, including those on zoonoses related to health in humans. The current research is a scientific survey on articles published in four databases, namely, PubMed, Bireme, Scielo and Lilacs. Results indicate that Brazil has a prominent position in international scientific production on this subject, with focus on Angiostrongylus cantonensis occurrences. PMID:28423090
The X-38 prototype of the Crew Return Vehicle is suspended under its giant 7,500-square-foot parafoi
NASA Technical Reports Server (NTRS)
2001-01-01
The X-38 prototype of the Crew Return Vehicle for the International Space Station is suspended under its giant 7,500-square-foot parafoil during its eighth free flight on Thursday, Dec. 13, 2001. A portion of the descent was flown by remote control by a NASA astronaut from a ground vehicle configured like the CRV's interior before the X-38 made an autonomous landing on Rogers Dry Lake.
Identification and properties of the M giant/X-ray system HD 154791 = 2A 1704+241
NASA Technical Reports Server (NTRS)
Garcia, M.; Baliunas, S. L.; Elvis, M.; Fabbiano, G.; Patterson, J.; Schwartz, D.; Doxsey, R.; Koenigsberger, G.; Swank, J.; Watson, M. G.
1983-01-01
The Aerial V X-ray source 2A 1704+241 (= 4U 1700+24 = 3A 1703+241) is identified with the M3 II star HD 154791. The identification is based on a precise X-ray position determined by the HEAO 1 scanning modulation collimator and the Einstein Observatory imaging proportional counter, together with a spectrum measured by the International Ultraviolet Explorer. The ultraviolet spectrum shows strong emission of C IV 1550 A, N v 1238 A, and Mg II 2800 A, which is very unusual among M giants. This is the first X-ray detection of an M giant which has a completely normal optical spectrum. The X-ray luminosity reaches three orders of magnitude above the mean upper limit for the coronal X-ray flux from M giants. Although there is no direct evidence for a binary system, since radial velocity variations have not been observed, it is shown that a plausible neutron star binary model can be constructed.
Human-Pathogenic Enterocytozoon bieneusi in Captive Giant Pandas (Ailuropoda melanoleuca) in China.
Li, Wei; Zhong, Zhijun; Song, Yuan; Gong, Chao; Deng, Lei; Cao, Yuying; Zhou, Ziyao; Cao, Xuefeng; Tian, Yinan; Li, Haozhou; Feng, Fan; Zhang, Yue; Wang, Chengdong; Li, Caiwu; Yang, Haidi; Huang, Xiangming; Fu, Hualin; Geng, Yi; Ren, Zhihua; Wu, Kongju; Peng, Guangneng
2018-04-26
Human and animal infections of Enterocytozoon bieneusi (E. bieneusi) have consistently been reported worldwide, garnering public attention; however, the molecular epidemiology of E. bieneusi in the giant panda remains limited. We surveyed captive giant pandas in China for the presence of E. bieneusi by using PCR and sequence analysis of the ribosomal internal transcribed spacer (ITS) revealing a 34.5% positive rate, with seven known genotypes (SC02, EpbC, CHB1, SC01, D, F, and Peru 6) and five novel genotypes (SC04, SC05, SC06, SC07, and SC08) identified. We similarly analyzed water samples, and E. bieneusi was detected in two samples, with genotype SC02 identified. Phylogenetic analysis revealed that CHB1 did not cluster with any recognized group, while the remaining genotypes belonged to group 1. The predominance of zoonotic group 1 genotypes indicates a public health threat that giant pandas could spread E. bieneusi to humans. The identification of E. bieneusi in water samples suggests giant pandas could contribute to water contamination. Effective control measures are therefore needed to minimize the contamination of the water and prevent a human microsporidiosis outbreak.
MISCIBILITY CALCULATIONS FOR WATER AND HYDROGEN IN GIANT PLANETS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Soubiran, François; Militzer, Burkhard
2015-06-20
We present results from ab initio simulations of liquid water–hydrogen mixtures in the range from 2 to 70 GPa and from 1000 to 6000 K, covering conditions in the interiors of ice giant planets and parts of the outer envelope of gas giant planets. In addition to computing the pressure and the internal energy, we derive the Gibbs free energy by performing a thermodynamic integration. For all conditions under consideration, our simulations predict hydrogen and water to mix in all proportions. The thermodynamic behavior of the mixture can be well described with an ideal mixing approximation. We suggest that amore » substantial fraction of water and hydrogen in giant planets may occur in homogeneously mixed form rather than in separate layers. The extent of mixing depends on the planet’s interior dynamics and its conditions of formation, in particular on how much hydrogen was present when icy planetesimals were delivered. Based on our results, we do not predict water–hydrogen mixtures to phase separate during any stage of the evolution of giant planets. We also show that the hydrogen content of an exoplanet is much higher if the mixed interior is assumed.« less
A Review of the Low-Frequency Waves in the Giant Magnetospheres
NASA Astrophysics Data System (ADS)
Delamere, P. A.
2016-02-01
The giant magnetospheres harbor a plethora of low-frequency waves with both internal (i.e., moons) and external (i.e., solar wind) source mechanisms. This chapter summarizes the observation of low-frequency waves at Jupiter and Saturn and postulates the underlying physics based on our understanding of magnetodisc generation mechanisms. The source mechanisms of ULF pulsations at the giant magnetospheres are numerous. The satellite-magnetosphere interactions and mass loading of corotational flows generate many low-frequency waves. Observations of low-frequency bursts of radio emissions serve as an excellent diagnostic for understanding satellite-magnetosphere interactions. The outward radial transport of plasma through the magnetodisc and related magnetic flux circulation is a significant source of ULF pulsations; however, it is uncertain how the radial transport mechanism compares with solar wind induced perturbations.
NASA Astrophysics Data System (ADS)
Deheuvels, S.; Doğan, G.; Goupil, M. J.; Appourchaux, T.; Benomar, O.; Bruntt, H.; Campante, T. L.; Casagrande, L.; Ceillier, T.; Davies, G. R.; De Cat, P.; Fu, J. N.; García, R. A.; Lobel, A.; Mosser, B.; Reese, D. R.; Regulo, C.; Schou, J.; Stahn, T.; Thygesen, A. O.; Yang, X. H.; Chaplin, W. J.; Christensen-Dalsgaard, J.; Eggenberger, P.; Gizon, L.; Mathis, S.; Molenda-Żakowicz, J.; Pinsonneault, M.
2014-04-01
Context. We still do not understand which physical mechanisms are responsible for the transport of angular momentum inside stars. The recent detection of mixed modes that contain the clear signature of rotation in the spectra of Kepler subgiants and red giants gives us the opportunity to make progress on this question. Aims: Our aim is to probe the radial dependence of the rotation profiles for a sample of Kepler targets. For this purpose, subgiants and early red giants are particularly interesting targets because their rotational splittings are more sensitive to the rotation outside the deeper core than is the case for their more evolved counterparts. Methods: We first extracted the rotational splittings and frequencies of the modes for six young Kepler red giants. We then performed a seismic modeling of these stars using the evolutionary codes Cesam2k and astec. By using the observed splittings and the rotational kernels of the optimal models, we inverted the internal rotation profiles of the six stars. Results: We obtain estimates of the core rotation rates for these stars, and upper limits to the rotation in their convective envelope. We show that the rotation contrast between the core and the envelope increases during the subgiant branch. Our results also suggest that the core of subgiants spins up with time, while their envelope spins down. For two of the stars, we show that a discontinuous rotation profile with a deep discontinuity reproduces the observed splittings significantly better than a smooth rotation profile. Interestingly, the depths that are found to be most probable for the discontinuities roughly coincide with the location of the H-burning shell, which separates the layers that contract from those that expand. Conclusions: We characterized the differential rotation pattern of six young giants with a range of metallicities, and with both radiative and convective cores on the main sequence. This will bring observational constraints to the scenarios of angular momentum transport in stars. Moreover, if the existence of sharp gradients in the rotation profiles of young red giants is confirmed, it is expected to help in distinguishing between the physical processes that could transport angular momentum in the subgiant and red giant branches. Appendices and Tables 3-9 are available in electronic form at http://www.aanda.org
NASA Astrophysics Data System (ADS)
Galicher, R.; Marois, C.; Macintosh, B.; Zuckerman, B.; Barman, T.; Konopacky, Q.; Song, I.; Patience, J.; Lafrenière, D.; Doyon, R.; Nielsen, E. L.
2016-10-01
Context. Radial velocity and transit methods are effective for the study of short orbital period exoplanets but they hardly probe objects at large separations for which direct imaging can be used. Aims: We carried out the international deep planet survey of 292 young nearby stars to search for giant exoplanets and determine their frequency. Methods: We developed a pipeline for a uniform processing of all the data that we have recorded with NIRC2/Keck II, NIRI/Gemini North, NICI/Gemini South, and NACO/VLT for 14 yr. The pipeline first applies cosmetic corrections and then reduces the speckle intensity to enhance the contrast in the images. Results: The main result of the international deep planet survey is the discovery of the HR 8799 exoplanets. We also detected 59 visual multiple systems including 16 new binary stars and 2 new triple stellar systems, as well as 2279 point-like sources. We used Monte Carlo simulations and the Bayesian theorem to determine that 1.05+2.80-0.70% of stars harbor at least one giant planet between 0.5 and 14 MJ and between 20 and 300 AU. This result is obtained assuming uniform distributions of planet masses and semi-major axes. If we consider power law distributions as measured for close-in planets instead, the derived frequency is 2.30+5.95-1.55%, recalling the strong impact of assumptions on Monte Carlo output distributions. We also find no evidence that the derived frequency depends on the mass of the hosting star, whereas it does for close-in planets. Conclusions: The international deep planet survey provides a database of confirmed background sources that may be useful for other exoplanet direct imaging surveys. It also puts new constraints on the number of stars with at least one giant planet reducing by a factor of two the frequencies derived by almost all previous works. Tables 11-15 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/594/A63
Gravity mode offset and properties of the evanescent zone in red-giant stars
NASA Astrophysics Data System (ADS)
Hekker, S.; Elsworth, Y.; Angelou, G. C.
2018-03-01
Context. The wealth of asteroseismic data for red-giant stars and the precision with which these data have been observed over the last decade calls for investigations to further understand the internal structures of these stars. Aim. The aim of this work is to validate a method to measure the underlying period spacing, coupling term, and mode offset of pure gravity modes that are present in the deep interiors of red-giant stars. We subsequently investigate the physical conditions of the evanescent zone between the gravity mode cavity and the pressure mode cavity. Methods: We implement an alternative mathematical description compared to what is used in the literature to analyse observational data and to extract the underlying physical parameters that determine the frequencies of mixed modes. This description takes the radial order of the modes explicitly into account, which reduces its sensitivity to aliases. Additionally, and for the first time, this method allows us to constrain the gravity mode offset ɛg for red-giant stars. Results: We find that this alternative mathematical description allows us to determine the period spacing ΔΠ and the coupling term q for the dipole modes within a few percent of values found in the literature. Additionally, we find that ɛg varies on a star-by-star basis and should not be kept fixed in the analysis. Furthermore, we find that the coupling factor is logarithmically related to the physical width of the evanescent region normalised by the radius at which the evanescent zone is located. Finally, the local density contrast at the edge of the core of red-giant branch models shows a tentative correlation with the offset ɛg. Conclusions: We are continuing to exploit the full potential of the mixed modes to investigate the internal structures of red-giant stars; in this case we focus on the evanescent zone. It remains, however, important to perform comparisons between observations and models with great care as the methods employed are sensitive to the range of input frequencies.
Three-dimensional reconstruction of the giant mimivirus particle with an x-ray free-electron laser.
Ekeberg, Tomas; Svenda, Martin; Abergel, Chantal; Maia, Filipe R N C; Seltzer, Virginie; Claverie, Jean-Michel; Hantke, Max; Jönsson, Olof; Nettelblad, Carl; van der Schot, Gijs; Liang, Mengning; DePonte, Daniel P; Barty, Anton; Seibert, M Marvin; Iwan, Bianca; Andersson, Inger; Loh, N Duane; Martin, Andrew V; Chapman, Henry; Bostedt, Christoph; Bozek, John D; Ferguson, Ken R; Krzywinski, Jacek; Epp, Sascha W; Rolles, Daniel; Rudenko, Artem; Hartmann, Robert; Kimmel, Nils; Hajdu, Janos
2015-03-06
We present a proof-of-concept three-dimensional reconstruction of the giant mimivirus particle from experimentally measured diffraction patterns from an x-ray free-electron laser. Three-dimensional imaging requires the assembly of many two-dimensional patterns into an internally consistent Fourier volume. Since each particle is randomly oriented when exposed to the x-ray pulse, relative orientations have to be retrieved from the diffraction data alone. We achieve this with a modified version of the expand, maximize and compress algorithm and validate our result using new methods.
2001-12-13
The X-38 prototype of the Crew Return Vehicle for the International Space Station is suspended under its giant 7,500-square-foot parafoil during its eighth free flight on Thursday, Dec. 13, 2001. A portion of the descent was flown by remote control by a NASA astronaut from a ground vehicle configured like the CRV's interior before the X-38 made an autonomous landing on Rogers Dry Lake.
Banfield, Laura; Jardine, Cynthia G
2013-01-01
International commitments exist for the safeguarding of health and the prevention of ill health. One of the earliest commitments is the Declaration of Alma-Ata (1978), which provides 5 principles guiding primary health care: equity, community participation, health promotion, intersectoral collaboration and appropriate technology. These broadly applicable international commitments are premised on the World Health Organization's multifaceted definition of health. The environment is one sector in which these commitments to safeguarding health can be applied. Giant Mine, a contaminated former gold mine in the Northwest Territories, Canada, represents potential threats to all aspects of health. Strategies for managing such threats usually involve an obligation to engage the affected communities through consultation. To examine the remediation and consultation process associated with Giant Mine within the context of commitments to safeguard health and well-being through adapting and applying the principles of primary health care. Semi-structured interviews with purposively selected key informants representing government proponents and community members were conducted. in reviewing themes which emerged from a series of interviews exploring the community consultation process for the remediation of Giant Mine, the principles guiding primary health were mapped to CONSULTATION IN the North: (a) "equity" is the capacity to fairly and meaningfully participate in the consultation; (b) "community participation" is the right to engage in the process through reciprocal dialogue; (c) "health promotion" represents the need for continued information sharing towards awareness; (d) "intersectoral collaboration" signifies the importance of including all stakeholders; and (e) "appropriate technology" is the need to employ the best remediation actions relevant to the site and the community. Within the context of mining remediation, these principles form an appropriate framework for viewing consultation as a means of meeting international obligations to safeguard health.
Determination of trace elements in the reproduction systems of some rare animals using pixe
NASA Astrophysics Data System (ADS)
Suqing, Chen; Nengming, Wang; Jianxuan, Chen; Dazhong, Zhang
In order to search for the significance of artificial feeding, reproduction and heredity, trace elements in the reproductive systems of some rare animals, including giant panda, lesser panda, marmot and river deer, have been determined. Typcial X-ray spectra of various samples are given. The elemental contents in ovary and testis of the giant panda and the lesser panda are calculated by means of yttrium as an internal standard. Elemental relative concentrations are calculated from peak areas in the spectra for thick samples. It is found that for the concentration of the elements Cr, Mn, Fe, Ni, Cu, As in the ovary there exist no significant different between the giant panda and the lesser panda. The concentration of Zn, however, shows a remakable difference. The importance of zinc in biological processes is discussed.
Formation of dust grains with impurities in red giant winds
NASA Technical Reports Server (NTRS)
Dominik, Carsten
1994-01-01
Among the several proposed carriers of diffuse interstellar bands (DIB's) are impurities in small dust grains, especially in iron oxide grains (Huffman 1977) and silicate grains (Huffman 1970). Most promising are single ion impurities since they can reproduce the observed band widths (Whittet 1992). These oxygen-rich grains are believed to originate mostly in the mass flows from red giants and in supernovae ejecta (e.g. Gehrz 1989). A question of considerable impact for the origin of DIB's is therefore, whether these grains are produced as mainly clean crystals or as some dirty materials. A formalism has been developed that allows tracking of the heterogeneous growth of a dust grain and its internal structure during the dust formation process. This formalism has been applied to the dust formation in the outflow from a red giant star.
Ma, Xiaoping; Li, Changcheng; Hou, Jiafa; Gu, Yu
2017-11-21
In order to better understand the possible role of fungi in giant panda reproduction and overall health, it is important to provide a baseline for the normal fungal composition in the reproductive system. Using morphology and internal transcribed spacer (ITS) sequence analysis, we systematically isolated and identified fungal species from the vagina, foreskin, and semen of 21 (11 males and 10 females) healthy giant pandas to understand the normal fungal flora of the genital tracts. A total of 76 fungal strains were obtained, representing 42 genera and 60 species. Among them 47 fungal strains were obtained from vaginal samples, 24 from foreskins, and 5 from semen samples. Several fungal strains were isolated from more than one sample. More fungal species were isolated from females from males. The predominant genera were Aspergillus, Trichosporon, and Penicillium, followed by Candida, Cladosporium, Sordariomycetes, and Diaporthe. The average number of strains in the female vagina was significantly higher than in the foreskin and semen of male. A total of 60 fungal species (belonging to 42 genera) were identified in the giant panda's genital tract. Some of the species were commonly shared in both males and females. These findings provide novel information on the fungal community in the reproductive tracts of giant pandas.
Magnetic braking of stellar cores in red giants and supergiants
DOE Office of Scientific and Technical Information (OSTI.GOV)
Maeder, André; Meynet, Georges, E-mail: andre.maeder@unige, E-mail: georges.meynet@unige.ch
2014-10-01
Magnetic configurations, stable on the long term, appear to exist in various evolutionary phases, from main-sequence stars to white dwarfs and neutron stars. The large-scale ordered nature of these fields, often approximately dipolar, and their scaling according to the flux conservation scenario favor a fossil field model. We make some first estimates of the magnetic coupling between the stellar cores and the outer layers in red giants and supergiants. Analytical expressions of the truncation radius of the field coupling are established for a convective envelope and for a rotating radiative zone with horizontal turbulence. The timescales of the internal exchangesmore » of angular momentum are considered. Numerical estimates are made on the basis of recent model grids. The direct magnetic coupling of the core to the extended convective envelope of red giants and supergiants appears unlikely. However, we find that the intermediate radiative zone is fully coupled to the core during the He-burning and later phases. This coupling is able to produce a strong spin down of the core of red giants and supergiants, also leading to relatively slowly rotating stellar remnants such as white dwarfs and pulsars. Some angular momentum is also transferred to the outer convective envelope of red giants and supergiants during the He-burning phase and later.« less
Nogueira, R L M; Faria, M H G; Osterne, R L V; Cavalcante, R B; Ribeiro, R A; Rabenhorst, S H B
2012-08-01
Central giant cell lesion is an uncommon benign jaw lesion, with uncertain aetiology, and variable clinical behaviour. Studies of molecular markers may help to understand the nature and behaviour of this lesion, and eventually may represent a target for pharmacological approaches to treatment. The aim of this study was to analyse the expression of glucocorticoid and calcitonin receptors in central giant cell lesions before and after treatment with intralesional steroid. Paraffin-embedded blocks from patients who underwent treatment with intralesional triamcinolone hexacetonide injections were stained immunohistochemically. Biological material from patients who underwent a surgical procedure after treatment were tested immunohistochemically. 18 cases (9 aggressive and 9 non-aggressive) were included. The difference in calcitonin receptor expression was not statistically significant between the aggressive and non-aggressive lesions and between the patients with a good response and those with a moderate/negative response to treatment. Glucocorticoid receptor expression in the multinucleated giant cells was higher in patients with a good response. It can be postulated that immunohistochemical staining for glucocorticoid receptors may provide a tool for selecting the therapeutic strategy. An H-score greater than 48 for glucocorticoid receptors in multinucleated giant cells predicted a good response in this study. Copyright © 2012 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
Huneeus-Cox, F; Fernandez, H L; Smith, B H
1966-09-01
The effects of internally and externally applied sulfhydryl reagents on the bioelectric properties of the giant axon of the squid Loligo pealeii and Dosidicus gigas were studied. Cysteine-HCl (400 mM, pH 7.3) was used to remove axoplasm from the perfusion channel. Oxidizing agents (1 to 60 mM) tended to increase the duration of the action potential and had a slow, irreversible blocking effect when perfused internally; the membrane potential was little affected. Reducing agents applied internally caused a decrease in the spike duration without affecting its height or the membrane potential, although at high concentrations there was reversible deterioration of the action potential. Both external and internal perfusion of mercaptide-forming reagents caused deterioration in the action and membrane potentials with conduction block occurring in 5 to 45 min. 2-mercaptoethanol reversed the effects. Thiol alkylating reagents, iodoacetate and iodoacetamide, were without effect. N-ethylmaleimide did, however, block. Tests with chelating agents for nonheme iron in the membrane brought about no change in the electrical parameters. The implications of the present findings with regard to the macromolecular mechanism of excitation are discussed.
Huneeus-Cox, F.; Fernandez, H. L.; Smith, B. H.
1966-01-01
The effects of internally and externally applied sulfhydryl reagents on the bioelectric properties of the giant axon of the squid Loligo pealeii and Dosidicus gigas were studied. Cysteine-HCl (400 mM, pH 7.3) was used to remove axoplasm from the perfusion channel. Oxidizing agents (1 to 60 mM) tended to increase the duration of the action potential and had a slow, irreversible blocking effect when perfused internally; the membrane potential was little affected. Reducing agents applied internally caused a decrease in the spike duration without affecting its height or the membrane potential, although at high concentrations there was reversible deterioration of the action potential. Both external and internal perfusion of mercaptide-forming reagents caused deterioration in the action and membrane potentials with conduction block occurring in 5 to 45 min. 2-mercaptoethanol reversed the effects. Thiol alkylating reagents, iodoacetate and iodoacetamide, were without effect. N-ethylmaleimide did, however, block. Tests with chelating agents for nonheme iron in the membrane brought about no change in the electrical parameters. The implications of the present findings with regard to the macromolecular mechanism of excitation are discussed. ImagesFigure 1 PMID:5970570
Physical Conditions and Exobiology Potential of Icy Satellites of the Giant Planets
NASA Astrophysics Data System (ADS)
Simakov, M. B.
2017-05-01
All giant planets of the Solar system have a big number of satellites. A small part of them consist very large bodies, quite comparable to planets of terrestrial type, but including very significant share of water ice. Galileo spacecraft has given indications, primarily from magnetometer and gravity data, of the possibility that three of Jupiter's four large moons, Europa, Ganymede and Callisto have internal oceans. Formation of such satellites is a natural phenomenon, and satellite systems definitely should exist at extrasolar planets. The most recent models of the icy satellites interior lead to the conclusion that a substantial liquid layer exists today under relatively thin ice cover inside. The putative internal water ocean provide some exobiological niches on these bodies. We can see all conditions needed for origin and evolution of biosphere - liquid water, complex organic chemistry and energy sources for support of biological processes - are on the moons. The existing of liquid water ocean within icy world can be consequences of the physical properties of water ice, and they neither require the addition of antifreeze substances nor any other special conditions. On Earth life exists in all niches where water exists in liquid form for at least a portion of the year. Possible metabolic processes, such as nitrate/nitrite reduction, sulfate reduction and methanogenesis could be suggested for internal oceans of Titan and Jovanian satellites. Excreted products of the primary chemoautotrophic organisms could serve as a source for other types of microorganisms (heterotrophes). Subglacial life may be widespread among such planetary bodies as satellites of extrasolar giant planets, detected in our Galaxy.
NASA Astrophysics Data System (ADS)
McDonald, I.; Zijlstra, A. A.; Sloan, G. C.; Kerins, E.; Lagadec, E.; Minniti, D.
2014-04-01
Variability is examined in over 2.6 million stars covering 11 square degrees of the core of the Sagittarius dwarf spheroidal galaxy (Sgr dSph) from Visible and Infrared Survey Telescope for Astronomy Z-band observations. Generally, pulsation on the Sgr dSph giant branches appears to be excited by the internal κ mechanism. Pulsation amplitudes appear identical between red and asymptotic (red giant branch/asymptotic giant branch) giant stars, and between unreddened carbon and oxygen-rich stars at the same luminosity. The lack of correlation between infrared excess and variability among oxygen-rich stars indicates that pulsations do not contribute significantly to wind driving in oxygen-rich stars in the Sgr dSph, though the low amplitudes of these stars mean this may not apply elsewhere. The dust-enshrouded carbon stars have the highest amplitudes of the stars we observe. Only in these stars does an external κ-mechanism-driven pulsation seem likely, caused by variations in their more opaque carbon-rich molecules or dust. This may allow pulsation driving of winds to be effective in carbon stars. Variability can be simplified to a power law (A ∝ L/T2), as in other systems. In total, we identify 3026 variable stars (with rms variability of δZ ≳ 0.015 mag), of which 176 are long-period variables associable with the upper giant branches of the Sgr dSph. We also identify 324 candidate RR Lyrae variables in the Sgr dSph and 340 in the outer Galactic bulge.
Weng, Z Y; Liu, Z Q; Ritchie, R O; Jiao, D; Li, D S; Wu, H L; Deng, L H; Zhang, Z F
2016-12-01
The giant panda׳s teeth possess remarkable load-bearing capacity and damage resistance for masticating bamboos. In this study, the hierarchical structure and mechanical behavior of the giant panda׳s tooth enamel were investigated under indentation. The effects of loading orientation and location on mechanical properties of the enamel were clarified and the evolution of damage in the enamel under increasing load evaluated. The nature of the damage, both at and beneath the indentation surfaces, and the underlying toughening mechanisms were explored. Indentation cracks invariably were seen to propagate along the internal interfaces, specifically the sheaths between enamel rods, and multiple extrinsic toughening mechanisms, e.g., crack deflection/twisting and uncracked-ligament bridging, were active to shield the tips of cracks from the applied stress. The giant panda׳s tooth enamel is analogous to human enamel in its mechanical properties, yet it has superior hardness and Young׳s modulus but inferior toughness as compared to the bamboo that pandas primarily feed on, highlighting the critical roles of the integration of underlying tissues in the entire tooth and the highly hydrated state of bamboo foods. Our objective is that this study can aid the understanding of the structure-mechanical property relations in the tooth enamel of mammals and further provide some insight on the food habits of the giant pandas. Copyright © 2016 Elsevier Ltd. All rights reserved.
The Evolution of Gas Giant Entropy During Formation by Runaway Accretion
NASA Astrophysics Data System (ADS)
Berardo, David; Cumming, Andrew; Marleau, Gabriel-Dominique
2017-01-01
We calculate the evolution of gas giant planets during the runaway gas accretion phase of formation, to understand how the luminosity of young giant planets depends on the accretion conditions. We construct steady-state envelope models, and run time-dependent simulations of accreting planets with the code Modules for Experiments in Stellar Astrophysics. We show that the evolution of the internal entropy depends on the contrast between the internal adiabat and the entropy of the accreted material, parametrized by the shock temperature T 0 and pressure P 0. At low temperatures ({T}0≲ 300-1000 {{K}}, depending on model parameters), the accreted material has a lower entropy than the interior. The convection zone extends to the surface and can drive a high luminosity, leading to rapid cooling and cold starts. For higher temperatures, the accreted material has a higher entropy than the interior, giving a radiative zone that stalls cooling. For {T}0≳ 2000 {{K}}, the surface-interior entropy contrast cannot be accommodated by the radiative envelope, and the accreted matter accumulates with high entropy, forming a hot start. The final state of the planet depends on the shock temperature, accretion rate, and starting entropy at the onset of runaway accretion. Cold starts with L≲ 5× {10}-6 {L}⊙ require low accretion rates and starting entropy, and the temperature of the accreting material needs to be maintained close to the nebula temperature. If instead the temperature is near the value required to radiate the accretion luminosity, 4π {R}2σ {T}04˜ ({GM}\\dot{M}/R), as suggested by previous work on radiative shocks in the context of star formation, gas giant planets form in a hot start with L˜ {10}-4 {L}⊙ .
Nakajima, Norio; Nagahiro, Shinji; Satomi, Junichiro; Tada, Yoshiteru; Nakajima, Kohei; Sogabe, Shu; Hanaoka, Mami; Matsubara, Shunji; Uno, Masaaki; Satoh, Koichi
2015-06-01
Recanalization has been reported in large or giant aneurysms of the internal carotid artery (ICA) addressed by high-flow bypass and endovascular treatment. Aneurysmal recanalization may be attributable to retrograde blood flow into the aneurysm through the ICA branches, such as the ophthalmic artery or the meningohypophyseal trunk, or through the surgically created bypass. We modified the endovascular treatment of aneurysms to prevent retrograde flow and evaluated the long-term efficacy of our method. We used a hybrid operative/endovascular technique to treat 5 patients with large or giant aneurysms arising from the C2-C4 segment of the ICA who presented with visual symptoms due to the mass effect of the aneurysm. To prevent retrograde flow into the aneurysm our modified endovascular treatment involves coil embolization of the aneurysmal orifice and the ICA, including the origin of the ophthalmic artery and meningohypophyseal trunk, and placement of a high-flow bypass using a radial artery graft. During the 5- to 12-year follow-up period, 4 aneurysms disappeared, and the other decreased in size. There were no subarachnoid hemorrhages. All bypass grafts remained patent. Visual preservation was achieved in 2 patients; 1 patient manifested visual improvement. Although 2 patients experienced transient neurological deficits we encountered no permanent complications in this series. The final modified Rankin scale of the 5 patients was 0 or 1. Prevention of retrograde flow into the aneurysm by coil embolization with high-flow bypass is a safe and effective method. It prevents the recanalization of large or giant ICA aneurysms. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Kohler, Susanna
2016-09-01
Weve recently discovered narrow sets of rings around two minor planets orbiting in our solar system. How did these rings form? A new study shows that they could be a result of close encounters between the minor planets and giants like Jupiter or Neptune.Unexpected Ring SystemsPositions of the centaurs in our solar system (green). Giant planets (red), Jupiter trojans (grey), scattered disk objects (tan) and Kuiper belt objects (blue) are also shown. [WilyD]Centaurs are minor planets in our solar system that orbit between Jupiter and Neptune. These bodies of which there are roughly 44,000 with diameters larger than 1 km have dynamically unstable orbits that cross paths with those of one or more giant planets.Recent occultation observations of two centaurs, 10199 Chariklo and 2060 Chiron, revealed that these bodies both host narrow ring systems. Besides our four giant planets, Chariklo and Chiron are the only other bodies in the solar system known to have rings. But how did these rings form?Scientists have proposed several models, implicating collisions, disruption of a primordial satellite, or dusty outgassing. But a team of scientists led by Ryuki Hyodo (Paris Institute of Earth Physics, Kobe University) has recently proposed an alternative scenario: what if the rings were formed from partial disruption of the centaur itself, after it crossed just a little too close to a giant planet?Tidal Forces from a GiantHyodo and collaborators first used past studies of centaur orbits to estimate that roughly 10% of centaurs experience close encounters (passing within a distance of ~2x the planetary radius) with a giant planet during their million-year lifetime. The team then performed a series of simulations of close encounters between a giant planet and a differentiated centaur a body in which the rocky material has sunk to form a dense silicate core, surrounded by an icy mantle.Some snapshots of simulation outcomes (click for a closer look!) for different initial states of the centaur internal structure, its spin, and the distance of closest approach of the centaur to the giant planet. Blue and red represent icy and silicate material, respectively. [Hyodo et al. 2016]The outcomes of the close encounters are diverse, depending strongly on the internal structure and spin of the minor planet and the geometry of the encounter. But the team finds that, in many scenarios, the centaur is only partially destroyed by tidal forces from the giant as it passes close by.In these cases the icy mantle and even some of the centaurs core can be ripped away and scattered, becoming gravitationally bound to the largest remaining clump of the core. The particles travel in highly eccentric orbits, gradually damping as they collide with each other and forming a disk around the remaining core. Further dynamical evolution of this disk could easily shape the rings that we observe today around Chariklo and Chiron.If Hyodo and collaborators scenario is correct, then Chariklo and Chiron are differentiated bodies with dense silicate cores, and their rings are either pure water ice, or a mixture of water ice and a small amount of silicate. Future observations of these minor planets will help to test this model and observations of other centaurs may discover yet more ring systems hiding in our solar system!BonusCheck out this awesomeanimation from ESO showing an artists impression of thering system around Chariklo! [ESO/L. Calada/M. Kornmesser]CitationRyuki Hyodo et al 2016 ApJ 828 L8. doi:10.3847/2041-8205/828/1/L8
Dr. Kenneth Sudduth: A giant pioneering precision agriculture
USDA-ARS?s Scientific Manuscript database
Dr. Ken Sudduth is nationally and internationally recognized for his precision agriculture research and leadership, especially in the areas of soil sensing and assessment of spatial variability for site-specific management. His many noteworthy contributions include novel techniques and methodology f...
Sodium influxes in internally perfused squid giant axon during voltage clamp.
Atwater, I; Bezanilla, F; Rojas, E
1969-05-01
1. An experimental method for measuring ionic influxes during voltage clamp in the giant axon of Dosidicus is described; the technique combines intracellular perfusion with a method for controlling membrane potential.2. Sodium influx determinations were carried out while applying rectangular pulses of membrane depolarization. The ratio ;measured sodium influx/computed ionic flux during the early current' is 0.92 +/- 0.12.3. Plots of measured sodium influx and computed ionic flux during the early current against membrane potential are very similar. There was evidence that the membrane potential at which the sodium influx vanishes is the potential at which the early current reverses.
Exploring the Ice Giants with JWST
NASA Astrophysics Data System (ADS)
Orton, Glenn S.; Fletcher, Leigh; Hammel, Heidi B.; Melin, Henrik; Guerlet, Sandrine; Greathouse, Thomas K.; Irwin, Patrick GJ
2017-06-01
The Ice Giants Uranus and Neptune are among the least-explored environments in our Solar System, having been visited only once, by Voyager 2 in 1986 and 1989, respectively. Their bulk properties and composition, intermediate between the hydrogen-rich gas giants and the smaller terrestrial worlds, make them representative of a planetary class that may be commonplace in other planetary systems. Furthermore, their small angular diameter, low atmospheric temperatures, and dynamic and ever-changing atmospheres make them tantalising infrared targets for JWST. This presentation will reveal the scientific rationale and requirements for a long-term program of JWST spectroscopic mapping of these two worlds. Specifically, the MIRI instrument can be used to determine the 3-dimensional temperature structure to understand (i) seasonal atmospheric circulation from the equator to the poles, (ii) the relation between temperatures, visible atmospheric banding and storm phenomena; and (iii) to discover the unknown circulations and wave phenomena shaping their middle atmospheres. JWST spectra will also allow us to search for and map chemical species produced from photochemistry (e.g., hydrocarbons derived from methane photolysis), from vertical mixing (e.g., disequilibrium species), and from external sources (e.g., HCN and oxygen compounds delivered by comets, ring rain and interplanetary dust). Furthermore, near-infrared imaging and spectroscopy with NIRCAM and NIRSpec will provide detailed characterisations of ice-giant cloud and haze formation and their evolution with time, as well as revealing how auroral processes (observed via H3+ emission) influence the middle atmosphere. JWST will not only enable intercomparison of these atmospheric processes on two very different worlds (Uranus with its extreme tilt and sluggish mixing; Neptune with its powerful internal heat source), but also mature our understanding of how ice giant phenomena compare to both gas giant and terrestrial atmospheric processes. We propose that preliminary mapping observations from the GTO programme will initiate a long-term programme of ice giant characterisation over the duration of JWST’s lifetime.
Shan, Lei; Wu, Qi; Wang, Le; Zhang, Lei; Wei, Fuwen
2018-03-01
Taste 2 receptors (TAS2R) mediate bitterness perception in mammals, thus are called bitter taste receptors. It is believed that these genes evolved in response to species-specific diets. The giant panda (Ailuropoda melanoleuca) and red panda (Ailurus fulgens styani) in the order Carnivora are specialized herbivores with an almost exclusive bamboo diet (>90% bamboo). Because bamboo is full of bitter tasting compounds, we hypothesized that adaptive evolution has occurred at TAS2R genes in giant and red pandas throughout the course of their dietary shift. Here, we characterized 195 TAS2R genes in 9 Carnivora species and examined selective pressures on these genes. We found that both pandas harbor more putative functional TAS2R genes than other carnivores, and pseudogenized TAS2R genes in the giant panda are different from the red panda. The purifying selection on TAS2R1, TAS2R9 and TAS2R38 in the giant panda, and TAS2R62 in the red panda, has been strengthened throughout the course of adaptation to bamboo diet, while selective constraint on TAS2R4 and TAS2R38 in the red panda is relaxed. Remarkably, a few positively selected sites on TAS2R42 have been specifically detected in the giant panda. These results suggest an adaptive response in both pandas to a dietary shift from carnivory to herbivory, and TAS2R genes evolved independently in the 2 pandas. Our findings provide new insight into the molecular basis of mammalian sensory evolution and the process of adaptation to new ecological niches. © 2017 The Authors. Integrative Zoology published by International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and John Wiley & Sons Australia, Ltd.
NASA Astrophysics Data System (ADS)
Themeßl, N.; Hekker, S.; Southworth, J.; Beck, P. G.; Pavlovski, K.; Tkachenko, A.; Angelou, G. C.; Ball, W. H.; Barban, C.; Corsaro, E.; Elsworth, Y.; Handberg, R.; Kallinger, T.
2018-05-01
The internal structures and properties of oscillating red-giant stars can be accurately inferred through their global oscillation modes (asteroseismology). Based on 1460 days of Kepler observations we perform a thorough asteroseismic study to probe the stellar parameters and evolutionary stages of three red giants in eclipsing binary systems. We present the first detailed analysis of individual oscillation modes of the red-giant components of KIC 8410637, KIC 5640750 and KIC 9540226. We obtain estimates of their asteroseismic masses, radii, mean densities and logarithmic surface gravities by using the asteroseismic scaling relations as well as grid-based modelling. As these red giants are in double-lined eclipsing binaries, it is possible to derive their independent dynamical masses and radii from the orbital solution and compare it with the seismically inferred values. For KIC 5640750 we compute the first spectroscopic orbit based on both components of this system. We use high-resolution spectroscopic data and light curves of the three systems to determine up-to-date values of the dynamical stellar parameters. With our comprehensive set of stellar parameters we explore consistencies between binary analysis and asteroseismic methods, and test the reliability of the well-known scaling relations. For the three red giants under study, we find agreement between dynamical and asteroseismic stellar parameters in cases where the asteroseismic methods account for metallicity, temperature and mass dependence as well as surface effects. We are able to attain agreement from the scaling laws in all three systems if we use Δνref, emp = 130.8 ± 0.9 μHz instead of the usual solar reference value.
NASA Astrophysics Data System (ADS)
Camerlenghi, Angelo; Lofi, Johanna; Aloisi, Vanni; Flecker, Rachel
2017-04-01
The origin of the Mediterranean salt giant is linked to an extraordinary event in the geological history of the Mediterranean region, commonly referred to as the Messinian Salinity Crisis (MSC). After 45 years of intense yet disunited research efforts, the international scientific community at large faces a unique opportunity to access the deep and marginal basins Messinian depositional successions in the Mediterranean through scientific drilling, namely through the Integrated Ocean Discovery Program (IODP) and the International Continental Drilling Program (ICDP). Scientific activity to promote scientific drilling offshore and onshore is in progress under the broad umbrella of the Uncovering a Salt Giant' IODP Multi-Platform Drilling proposal, that has generated the Deep-Sea Records of the Messinian Salinity Crisis (DREAM) site-specific pre-proposal for riserless drilling on Messinian marginal basins and the related ICDP-IODP amphibious initiative Investigating Miocene Mediterranean- Atlantic gateway exchange (IMMAGE). Scientific networking has begun to establish a broad cross-disciplinary research community embracing geology, geophysics, geochemistry, microbiology, and paleoclimatology. Formal networking activities represent an opportunity for the scientific community to share objectives, data, expertise and tools with industry since there is considerable interest in oil and gas exploration, and consequent hazards, targeting the Mediterranean's deep salt deposits. With the acronym MEDSALT, we have established two networks working in close cooperation: (1) COST Action CA15103 Uncovering the Mediterranean salt giant (MEDSALT) (https://medsalt.eu/) is a 4-year long network established in May 2016 comprising scientific institutions from 28 states. This COST Action will provide an opportunity to develop further our knowledge of salt rock formation addressing four overarching scientific questions: a) What are the causes, timing and emplacement mechanisms of the Mediterranean salt giant? b) What are the factors responsible for and the socio-economic consequences of early salt deformation and fluid flow across and out of the halite layer? c) Do salt giants promote the development of a phylogenetically diverse and exceptionally active deep biosphere? d) What are the mechanisms underlying the spectacular vertical motions inside basins and their margins? (2) ANR Project 'Uncovering the Mediterranean Salt Giant' (MEDSALT) aims at establishing networking action to prepare an Integrated Ocean Discovery Program (IODP) full proposal to drill the Mediterranean Salt Giant with the R/V JOIDES Resolution. This 18-month long network consists of a core group of 22 scientists from 10 countries working in close cooperation with the brother COST Action MEDSALT. These inter-sectorial and multinational cooperation networks comprise a critical mass of both experienced and early-career researchers from Europe and beyond. The goal will be achieved through capacity building, researchers' mobility, skills development, knowledge exchange and scientific networking.
Shearn-Bochsler, Valerie; Green, David Earl; Converse, K.A.; Docherty, D.E.; Thiel, T.; Geisz, H.N.; Fraser, William R.; Patterson-Fraser, Donna L.
2008-01-01
The Southern giant petrel (Macronectes giganteus) is declining over much of its range and currently is listed as vulnerable to extinction by the International Union for the Conservation of Nature (IUCN). Island-specific breeding colonies near Palmer Station, Antarctica, have been monitored for over 30 years, and because this population continues to increase, it is critically important to conservation. In austral summer 2004, six diseased giant petrel chicks were observed in four of these colonies. Diseased chicks were 6a??9 weeks old and had multiple proliferative nodules on their bills and skin. One severely affected chick was found dead on the nest and was salvaged for necropsy. Histopathological examination of nodules from the dead chick revealed epithelial cell hyperplasia and hypertrophy with numerous eosinophilic intracytoplasmic inclusions (B??llinger bodies). A poxvirus was isolated from multiple nodules. Poxviral infection has not been reported in this species, and the reason for its emergence and its potential impact on the population are not yet known.
Makarov, M S; Chentsov, Iu S
2010-01-01
Giant nuclei from salivary glands of Chironomus plumosus were treated in situ with detergent, 2 M NaCl and nucleases in order to reveal residual nuclear matrix proteins (NMP). It was shown, that preceding stabilization of non-histone proteins with 2 mM CuCl2 allowed to visualize the structure of polythene chromosomes at every stage of the extraction of histones and DNA. Stabilized NPM of polythene chromosomes maintains their morphology and banding patterns, which is observed by light and electron microscopy, whereas internal fibril net or residual nucleoli are not found. In stabilized NPM of polythene chromosomes, topoisomerase IIalpha and SMC1 retain their localization that is typical of untreated chromosomes. NPM of polythene chromosomes also includes sites of DNA replication, visualized with BrDU incubation, and some RNA-components. So, we can conclude that structure of NPM from giant nuclei is equal to NPM from normal interphase nuclei, and that morphological features of polythene chromosomes depend on the presence of NMP.
Telemetry research on elusive wildlife: A synthesis of studies on giant pandas.
Connor, Thomas; Hull, Vanessa; Liu, Jianguo
2016-07-01
Telemetry studies that track animals through space and time can lead to advances in scientific understanding that are vital in conservation efforts. For example, telemetry studies of the giant panda (Ailuropoda melanoleuca) have shed light on many aspects of panda biology, but small sample sizes in each separate study make it difficult to draw broad conclusions. To overcome this problem we conducted the first synthesis of all 5 panda telemetry studies conducted to date. Using these data we investigated patterns in 6 main topics: home range, space-use interactions, core areas, movement patterns, seasonal migration and natal dispersal. We found that panda home range sizes do not vary between 2 main mountain ranges (Qionglai and Qinling), as was previously believed. Our results also suggest that female pandas increase their movement in the mating season: a behavior typically attributed only to males. We found and summarized telemetry and genetic evidence for female natal dispersal in the giant panda. Our synthesis highlights the need for additional research relating panda behavior to human disturbance factors, and can aid future studies on giant pandas as well as other species. © 2016 International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and John Wiley & Sons Australia, Ltd.
Nogueira, R L M; Teixeira, R C; Cavalcante, R B; Ribeiro, R A; Rabenhosrt, S H B
2010-12-01
Central giant-cell granulomas are benign, but occasionally aggressive, lesions that traditionally have been treated surgically. 21 cases of central giant-cell granuloma of the jaw were treated with intralesional injection of corticosteroids. The treatment protocol adopted was intralesional injection of 20mg/ml triamcinolone hexacetonide diluted in an anaesthetic solution of 2% lidocaine/epinephrine 1:200,000 in the proportion 1:1; 1.0ml of the solution was infiltrated for every 1cm(3) of radiolucid area of the lesion, totalling 6 biweekly applications. Ten patients had aggressive lesions and 11 nonaggressive. Two patients showed a negative response to the treatment and underwent surgical resection, 4 showed a moderate response and 15 a good response. 8 of the 19 who had a moderate-to-good response to the drug treatment underwent osteoplasty to reestablish facial aesthetics. In these cases, only mature or dysplastic bone was observed, with the presence or absence of rare giant multinucleated cells. The advantages of this therapy are its less-invasive nature, the probable lower cost to the patient, lower risk and the ability to treat the lesion surgically in the future, if necessary. Copyright © 2010 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
Sodium influxes in internally perfused squid giant axon during voltage clamp
Atwater, I.; Bezanilla, F.; Rojas, E.
1969-01-01
1. An experimental method for measuring ionic influxes during voltage clamp in the giant axon of Dosidicus is described; the technique combines intracellular perfusion with a method for controlling membrane potential. 2. Sodium influx determinations were carried out while applying rectangular pulses of membrane depolarization. The ratio `measured sodium influx/computed ionic flux during the early current' is 0·92 ± 0·12. 3. Plots of measured sodium influx and computed ionic flux during the early current against membrane potential are very similar. There was evidence that the membrane potential at which the sodium influx vanishes is the potential at which the early current reverses. PMID:5767887
Internal motions of HII regions and giant HII regions
NASA Technical Reports Server (NTRS)
Chu, You-Hua; Kennicutt, Robert C., Jr.
1994-01-01
We report new echelle observations of the kinematics of 30 HII regions in the Large Magellanic Clouds (LMC), including the 30 Doradus giant HII region. All of the HII regions possess supersonic velocity dispersions, which can be attributed to a combination of turbulent motions and discrete velocity splitting produced by stellar winds and/or embedded supernova remnants (SNRs). The core of 30 Dor is unique, with a complex velocity structure that parallels its chaotic optical morphology. We use our calibrated echelle data to measure the physical properties and energetic requirements of these velocity structures. The most spectacular structures in 30 Dor are several fast expanding shells, which appear to be produced at least partially by SNRs.
Effects of the dipolar form of phloretin on potassium conductance in squid giant axons.
Strichartz, G R; Oxford, G S; Ramon, F
1980-01-01
The effects of phloretin on membrane ionic conductances have been studied in the giant axon of the squid, Loligo pealei. Phloretin reversibly suppresses the potassium and sodium conductances and modifies their dependence on membrane potential (Em). Its effects on the potassium conductance (GK) are much greater than on the sodium conductance; no effects on sodium inactivation are observed. Internal perfusion of phloretin produces both greater shifts in GK(Em) and greater reductions maximum GK than does external perfusion; the effect of simultaneous internal and external perfusion is little greater than that of internal perfusion alone. Lowering the internal pH, which favors the presence of the neutral species of weakly acidic phloretin (pKa 7.4), potentiates the actions of internally perfused phloretin. Other organic cations with dipole moments similar to phloretin's have little effect on either potassium or sodium conductances in squid axons. These results can be explained by either of two mechanisms; on postulates a phloretin "receptor" near the voltage sensor component of the potassium channel which is accessible to drug molecules applied at either the outer or inner membrane surface and is much more sensitive to the neutral than the negatively charged form of the drug. The other mechanism proposes that neutral phloretin molecules are dispersed in an ordered array in the membrane interior, producing a diffuse dipole field which modifies potassium channel gating. Different experimental results support these two mechanisms, and neither hypothesis can be disproven. PMID:6266534
Glucose transport machinery reconstituted in cell models.
Hansen, Jesper S; Elbing, Karin; Thompson, James R; Malmstadt, Noah; Lindkvist-Petersson, Karin
2015-02-11
Here we demonstrate the production of a functioning cell model by formation of giant vesicles reconstituted with the GLUT1 glucose transporter and a glucose oxidase and hydrogen peroxidase linked fluorescent reporter internally. Hence, a simplified artificial cell is formed that is able to take up glucose and process it.
Glucose Transport Machinery Reconstituted in Cell Models
Hansen, Jesper S.; Elbing, Karin; Thompson, James R.; Malmstadt, Noah
2015-01-01
Here we demonstrate the production of a functioning cell model by formation of giant vesicles reconstituted with the GLUT1 glucose transporter and a glucose oxidase and hydrogen peroxidase linked fluorescent reporter internally. Hence, a simplified artificial cell is formed that is able to take up glucose and process it. PMID:25562394
Education and Training: Have the Japanese Beaten Us Again?
ERIC Educational Resources Information Center
Rehder, Robert R.
1983-01-01
Japan is often likened to a giant corporation--Japan Inc.--in which the educational credentials of its employees largely determine their social and economic status. This first international report of 1983 discusses why the U.S. should study the pros and cons of the Japanese educational system. (SSH)
Isotopic ratios D/H and 15N/14N in giant planets
NASA Astrophysics Data System (ADS)
Marboeuf, Ulysse; Thiabaud, Amaury; Alibert, Yann; Benz, Willy
2018-04-01
The determination of isotopic ratios in planets is important since it allows us to investigate the origins and initial composition of materials. The present work aims to determine the possible range of values for isotopic ratios D/H and 15N/14N in giant planets. The main objective is to provide valuable theoretical assumptions on the isotopic composition of giant planets, their internal structure, and the main reservoirs of species. We use models of ice formation and planet formation that compute the composition of ices and gas accreted in the core and the envelope of planets. Assuming a single initial value for isotopic ratios in volatile species, and disruption of planetesimals in the envelope of gaseous planets, we obtain a wide variety of D/H and 15N/14N ratios in low-mass planets (≤100 Mearth) due to the migration pathway of planets, the accretion time of gas species whose relative abundance evolves with time, and isotope exchanges among species. If giant planets with mass greater than 100 Mearth have solar isotopic ratios such as Jupiter and Saturn due to their higher envelope mass, Neptune-type planets present values ranging between one and three times the solar value. It seems therefore difficult to use isotopic ratios in the envelope of these planets to get information about their formation in the disc. For giant planets, the ratios allow us to constrain the mass fraction of volatile species in the envelope needed to reproduce the observational data by assuming initial values for isotopic ratios in volatile species.
INTERNAL ROTATION OF THE RED-GIANT STAR KIC 4448777 BY MEANS OF ASTEROSEISMIC INVERSION
DOE Office of Scientific and Technical Information (OSTI.GOV)
Di Mauro, M. P.; Cardini, D.; Ventura, R.
We study the dynamics of the stellar interior of the early red-giant star KIC 4448777 by asteroseismic inversion of 14 splittings of the dipole mixed modes obtained from Kepler observations. In order to overcome the complexity of the oscillation pattern typical of red-giant stars, we present a procedure to extract the rotational splittings from the power spectrum. We find not only that the core rotates from a minimum of 8 to a maximum of 17 times faster than the surface, confirming previous inversion results generated for other red giants (Deheuvels et al.), but we also estimate the variation of the angularmore » velocity within the helium core with a spatial resolution of 0.001R and verify the hypothesis of a sharp discontinuity in the inner stellar rotation. The results show that the entire core rotates rigidly and provide evidence for an angular velocity gradient around the base of the hydrogen-burning shell; however, we do not succeed in characterizing the rotational slope, due to the intrinsic limits of the applied techniques. The angular velocity, from the edge of the core, appears to decrease with increasing distance from the center, reaching an average value in the convective envelope of 68 ± 22 nHz. We conclude that a set of data that includes only dipolar modes is sufficient to infer quite accurately the rotation of a red giant not only in the dense core but also, with a lower level of confidence, in part of the radiative region and in the convective envelope.« less
NASA Astrophysics Data System (ADS)
Rymer, A. M.; Arridge, C. S.; Masters, A.; Turtle, E. P.; Simon, A. A.; Hofstadter, M. D.; Turrini, D.; Politi, R.
2015-12-01
The Ice Giants in our solar system, Uranus and Neptune, are fundamentally different from their Gas Giant siblings Jupiter and Saturn, from the different proportions of rock and ice to the configuration of their planetary magnetic fields. Kepler space telescope discoveries of exo-planets indicate that planets of this type are among the most ubiquitous universally and therefore a future mission to explore the nature of the Ice Giants in our own solar system will provide insights into the nature of extra-solar system objects in general. Uranus has the smallest self- luminosity of all the planets, potentially related to catastrophic events early in the planet's history, which also may explain Uranus' large obliquity. Uranus' atmosphere is subject to extreme seasonal forcing making it unique in the Solar System. Neptune is also unique in a number of ways, notably its large moon Triton which is likely a captured Kuiper Belt Object and one of only two moons in the solar system with a robustly collisional atmosphere. Similar to Uranus, the angle between the solar wind and the magnetic dipole axis is subject to large-amplitude variations on both diurnal and seasonal timescales, but peculiarly it has one of the quietest magnetospheres of the solar system, at least according to Voyager 2, the only spacecraft to encounter Neptune to date. A comprehensive mission, as advocated in the Decadal Survey, would provide enormous science return but is also challenging and expensive. In this presentation we will discuss mission scenarios and suggest how collaboration between disciplines and internationally can help us to pursue a mission that includes Ice Giant exploration.
Population genetics of Enterocytozoon bieneusi in captive giant pandas of China.
Li, Wei; Song, Yuan; Zhong, Zhijun; Huang, Xiangming; Wang, Chengdong; Li, Caiwu; Yang, Haidi; Liu, Haifeng; Ren, Zhihua; Lan, Jingchao; Wu, Kongju; Peng, Guangneng
2017-10-18
Most studies on Enterocytozoon bieneusi are conducted based on the internal transcribed spacer (ITS) region of the rRNA gene, whereas some have examined E. bieneusi population structures. Currently, the population genetics of this pathogen in giant panda remains unknown. The objective of this study was to determine the E. bieneusi population in captive giant pandas in China. We examined 69 E. bieneusi-positive specimens from captive giant pandas in China using five loci (ITS, MS1, MS3, MS4 and MS7) to infer E. bieneusi population genetics. For multilocus genotype (MLG) analysis of E. bieneusi-positive isolates, the MS1, MS3, MS4, and MS7 microsatellite and minisatellite loci were amplified and sequenced in 48, 45, 50 and 47 specimens, respectively, generating ten, eight, nine and five types. We successfully amplified 36 specimens and sequenced all five loci, forming 24 MLGs. Multilocus sequence analysis revealed a strong and significant linkage disequilibrium (LD), indicating a clonal population. This result was further supported by measurements of pairwise intergenic LD and a standardized index of association (I S A ) from allelic profile data. The analysis in STRUCTURE suggested three subpopulations in E. bieneusi, further confirmed using right's fixation index (F ST ). Subpopulations 1 and 2 exhibited an epidemic structure, whereas subpopulation 3 had a clonal structure. Our results describe E. bieneusi population genetics in giant pandas for the first time, improving the current understanding E. bieneusi epidemiology in the studied region. These data also benefit future studies exploring potential transmission risks from pandas to other animals, including humans.
Waking a sleeping giant: the tobacco industry's response to the polonium-210 issue.
Muggli, Monique E; Ebbert, Jon O; Robertson, Channing; Hurt, Richard D
2008-09-01
The major tobacco manufacturers discovered that polonium was part of tobacco and tobacco smoke more than 40 years ago and attempted, but failed, to remove this radioactive substance from their products. Internal tobacco industry documents reveal that the companies suppressed publication of their own internal research to avoid heightening the public's awareness of radioactivity in cigarettes. Tobacco companies continue to minimize their knowledge about polonium-210 in cigarettes in smoking and health litigation. Cigarette packs should carry a radiation-exposure warning label.
Horn, G
1997-12-01
The Frechet extender, initially proposed and successfully used in scalp reductions, can have many other indications in reconstructive surgery. This paper describes the preliminary results obtained after using this internal tissue extender in the treatment of a limb burn scar and a congenital giant naevus of the back. After a 3 month follow-up, these results are excellent. This procedure gives good results especially when there is a bony support underneath the skin to be treated.
Giant molecular cloud collisions as triggers of star formation. VI. Collision-induced turbulence
NASA Astrophysics Data System (ADS)
Wu, Benjamin; Tan, Jonathan C.; Nakamura, Fumitaka; Christie, Duncan; Li, Qi
2018-05-01
We investigate collisions between giant molecular clouds (GMCs) as potential generators of their internal turbulence. Using magnetohydrodynamic (MHD) simulations of self-gravitating, magnetized, turbulent GMCs, we compare kinematic and dynamic properties of dense gas structures formed when such clouds collide compared to those that form in non-colliding clouds as self-gravity overwhelms decaying turbulence. We explore the nature of turbulence in these structures via distribution functions of density, velocity dispersions, virial parameters, and momentum injection. We find that the dense clumps formed from GMC collisions have higher effective Mach number, greater overall velocity dispersions, sustain near-virial equilibrium states for longer times, and are the conduit for the injection of turbulent momentum into high density gas at high rates.
Giant molecular cloud collisions as triggers of star formation. VI. Collision-induced turbulence
NASA Astrophysics Data System (ADS)
Wu, Benjamin; Tan, Jonathan C.; Nakamura, Fumitaka; Christie, Duncan; Li, Qi
2018-01-01
We investigate collisions between giant molecular clouds (GMCs) as potential generators of their internal turbulence. Using magnetohydrodynamic (MHD) simulations of self-gravitating, magnetized, turbulent GMCs, we compare kinematic and dynamic properties of dense gas structures formed when such clouds collide compared to those that form in non-colliding clouds as self-gravity overwhelms decaying turbulence. We explore the nature of turbulence in these structures via distribution functions of density, velocity dispersions, virial parameters, and momentum injection. We find that the dense clumps formed from GMC collisions have higher effective Mach number, greater overall velocity dispersions, sustain near-virial equilibrium states for longer times, and are the conduit for the injection of turbulent momentum into high density gas at high rates.
NASA Astrophysics Data System (ADS)
Puli, Venkata Sreenivas; Adireddy, Shiva; Kothakonda, Manish; Elupula, Ravinder; Chrisey, Douglas B.
This paper reports on synthesis of polycrystalline complex perovskite CaCu3Ti4O12 (as CCTO) ceramic powders prepared by a sol-gel auto combustion method at different sintering temperatures and sintering times, respectively. The effect of sintering time on the structure, morphology, dielectric and electrical properties of CCTO ceramics is investigated. Tuning the electrical properties via different sintering times is demonstrated for ceramic samples. X-ray diffraction (XRD) studies confirm perovskite-like structure at room temperature. Abnormal grain growth is observed for ceramic samples. Giant dielectric permittivity was realized for CCTO ceramics. High dielectric permittivity was attributed to the internal barrier layer capacitance (IBLC) model associated with the Maxwell-Wagner (MW) polarization mechanism.
Middleweight black holes found at last
NASA Astrophysics Data System (ADS)
Clery, Daniel
2018-06-01
How did giant black holes grow so big? Astronomers have long had evidence of baby black holes with masses of no more than tens of suns, and of million- or billion-solar-mass behemoths lurking at the centers of galaxies. But middle-size ones, weighing thousands or tens of thousands of suns, seemed to be missing. Their absence forced theorists to propose that supermassive black holes didn't grow gradually by slowly consuming matter, but somehow emerged as ready-made giants. Now, astronomers appear to have located some missing middleweights. An international team has scoured an archive of galaxy spectra and found more than 300 small galaxies that have the signature of intermediate mass black holes in their cores, opening new questions for theorists.
Gilgien, Matthias; Crivelli, Philip; Spörri, Jörg; Kröll, Josef; Müller, Erich
2015-01-01
World Cup (WC) alpine ski racing consists of four main competition disciplines (slalom, giant slalom, super-G and downhill), each with specific course and terrain characteristics. The International Ski Federation (FIS) has regulated course length, altitude drop from start to finish and course setting in order to specify the characteristics of the respective competition disciplines and to control performance and injury-related aspects. However to date, no detailed data on course setting and its adaptation to terrain is available. It is also unknown how course and terrain characteristics influence skier speed. Therefore, the aim of the study was to characterize course setting, terrain geomorphology and their relationship to speed in male WC giant slalom, super-G and downhill. The study revealed that terrain was flatter in downhill compared to the other disciplines. In all disciplines, variability in horizontal gate distance (gate offset) was larger than in gate distance (linear distance from gate to gate). In giant slalom the horizontal gate distance increased with terrain inclination, while super-G and downhill did not show such a connection. In giant slalom and super-G, there was a slight trend towards shorter gate distances as the steepness of the terrain increased. Gates were usually set close to terrain transitions in all three disciplines. Downhill had a larger proportion of extreme terrain inclination changes along the skier trajectory per unit time skiing than the other disciplines. Skier speed decreased with increasing steepness of terrain in all disciplines except for downhill. In steep terrain, speed was found to be controllable by increased horizontal gate distances in giant slalom and by shorter gate distances in giant slalom and super-G. Across the disciplines skier speed was largely explained by course setting and terrain inclination in a multiple linear model. PMID:25760039
Do all barium stars have a white dwarf companion?
NASA Technical Reports Server (NTRS)
Dominy, J. F.; Lambert, D. L.
1983-01-01
International Ultraviolet Explorer short-wavelength, low-dispersion spectra were analyzed for four barium, two mild barium, and one R-type carbon star in order to test the hypothesis that the barium and related giants are produced by mass transfer from a companion now present as a white dwarf. An earlier tentative identification of a white dwarf companion to the mild barium star Zeta Cyg is confirmed. For the other stars, no ultraviolet excess attributable to a white dwarf is seen. Limits are set on the bolometric magnitude and age of a possible white dwarf companion. Since the barium stars do not have obvious progenitors among main-sequence and subgiant stars, mass transfer must be presumed to occur when the mass-gaining star is already on the giant branch. This restriction, and the white dwarf's minimum age, which is greater than 8 x 10 to the 8th yr, determined for several stars, effectively eliminates the hypothesis that mass transfer from an asymptotic giant branch star creates a barium star. Speculations are presented on alternative methods of producing a barium star in a binary system.
A possible giant planet orbiting the cataclysmic variable LX Ser
NASA Astrophysics Data System (ADS)
Li, Kai; Hu, Shaoming; Zhou, Jilin; Wu, Donghong; Guo, Difu; Jiang, Yunguo; Gao, Dongyang; Chen, Xu; Wang, Xianyu
2017-04-01
LX Ser is a deeply eclipsing cataclysmic variable with an orbital period of 0.1584325 d. 62 new eclipse times were determined by our observations and the AAVSO International Data base. Combining all available eclipse times, we analyzed the O - C behavior of LX Ser. We found that the O - C diagram of LX Ser shows a sinusoidal oscillation with a period of 22.8 yr and an amplitude of 0.00035 d. Two mechanisms (i.e., the Applegate mechanism and the light-travel time effect) are applied to explain the cyclic modulation. We found that it is difficult to apply the Applegate mechanism to explain the cyclic oscillation in the orbital period. Therefore, the cyclic period change is most likely to be caused by the light-travel time effect due to the presence of a third body. The mass of the tertiary component was determined to be M3 ∼ 7.5 MJup. We supposed that the tertiary companion is plausibly a giant planet. The stability of the giant planet was checked, and we found that the multiple system is stable.
Inside the lifestyle of the virophage.
Desnues, C; Raoult, D
2010-01-01
We sought to better characterize Sputnik, the first isolated virophage, and to analyze its parasitic lifestyle during co-infection with Marseillevirus (a new giant virus) in Acanthamoeba castellanii. A combination of electron microscopy, immunofluorescence microscopy, and real-time PCR was used to characterize the kinetics of the viral replication cycle. RT-PCR was performed to detect RNAs inside the Sputnik virions. Sputnik is a new viral entity carrying an almost complete ready-to-use set of viral RNAs (20 out of 21). Sputnik does not replicate with Marseillevirus but delays its replication cycle. While Marseillevirus is successfully internalized by A. castellanii following co-infections with Mamavirus and Sputnik, it does not initiate a replication cycle. In contrast, both Marseillevirus and Mamavirus can replicate in the amoeba in case of co-infection, but the development of one is exclusive from the other inside a single amoeba cell. This work provides new insight into the Sputnik replication cycle with another giant virus and confirms that Sputnik is a virophage. It shows new dimensions of the interactions existing among giant viruses. Copyright 2010 S. Karger AG, Basel.
On 7Li Enrichment by Low-Mass Metal-Poor Red Giant Branch Stars.
de La Reza R; da Silva L; Drake; Terra
2000-06-01
First-ascent red giants with strong and very strong Li lines have just been discovered in globular clusters. Using the stellar internal prompt (7)Li enrichment-mass-loss scenario, we explore the possibility of (7)Li enrichment in the interstellar matter of the globular cluster M3 produced by these Li-rich giants. We found that enrichment as large as 70% or more compared to the initial (7)Li content of M3 can be obtained during the entire life of this cluster. However, because M3 will cross into the Galactic plane several times, the new (7)Li will be very probably removed by ram pressure into the disk. Globular clusters appear then as possible new sources of (7)Li in the Galactic disk. It is also suggested that the known Na/Al variations in stars of globular clusters could be somehow related to the (7)Li variations and that the cool bottom process mixing mechanism acting in the case of (7)Li could also play a role in the case of Na and Al surface enrichments.
Amoeba/amoebal symbiont genetic transfers: lessons from giant virus neighbours.
Thomas, Vincent; Greub, Gilbert
2010-01-01
Free-living amoebae serve as hosts for a variety of amoebae-resisting microorganisms, including giant viruses and certain bacteria. The latter include symbiotic bacteria as well as bacteria exhibiting a pathogenic phenotype towards amoebae. Amoebae-resisting bacteria have been shown to be widespread in water and to use the amoebae as a reservoir, a replication niche, a protective armour as well as a training ground to select virulence traits allowing survival in the face of microbicidal effects of macrophages, the first line of defense against invading pathogens. More importantly, amoebae play a significant role as a melting pot for genetic exchanges. These ecological and evolutionary roles of amoebae might also be at play for giant viruses and knowledge derived from the study of amoebae-resisting bacteria is useful for the study and understanding of interactions between amoebae and giant viruses. This is especially important since some genes have spread in all domains of life and the exponential availability of eukaryotic genomes and metagenomic sequences will allow researchers to explore these genetic exchanges in a more comprehensive way, thus completely changing our perception of the evolutionary history of organisms. Thus, a large part of this review is dedicated to report current known gene exchanges between the different amoebae-resisting organisms and between amoebae and the internalized bacteria. Copyright 2010 S. Karger AG, Basel.
Genome packaging in EL and Lin68, two giant phiKZ-like bacteriophages of P. aeruginosa
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sokolova, O.S., E-mail: sokolova@mail.bio.msu.ru; A.V. Shoubnikov Institute of Crystallography RAS, Moscow; Shaburova, O.V.
A unique feature of the Pseudomonas aeruginosa giant phage phiKZ is its way of genome packaging onto a spool-like protein structure, the inner body. Until recently, no similar structures have been detected in other phages. We have studied DNA packaging in P. aeruginosa phages EL and Lin68 using cryo-electron microscopy and revealed the presence of inner bodies. The shape and positioning of the inner body and the density of the DNA packaging in EL are different from those found in phiKZ and Lin68. This internal organization explains how the shorter EL genome is packed into a large EL capsid, whichmore » has the same external dimensions as the capsids of phiKZ and Lin68. The similarity in the structural organization in EL and other phiKZ-like phages indicates that EL is phylogenetically related to other phiKZ-like phages, and, despite the lack of detectable DNA homology, EL, phiKZ, and Lin68 descend from a common ancestor. - Highlights: • We performed a comparative structural study of giant P. aeruginosa phages: EL, Lin68 and phiKZ. • We revealed that the inner body is a common feature in giant phages. • The phage genome size correlates with the overall dimensions of the inner body.« less
Han, Han; Wei, Wei; Nie, Yonggang; Zhou, Wenliang; Hu, Yibo; Wu, Qi; Wei, Fuwen
2016-11-01
Stable isotope analysis is very useful in animal ecology, especially in diet reconstruction and trophic studies. Differences in isotope ratios between consumers and their diet, termed discrimination factors, are essential for studies of stable isotope ecology and are species-specific and tissue-specific. Given the specialized bamboo diet and clear foraging behavior, here, we calculated discrimination factors for carbon and nitrogen isotopes from diet to tissues (tooth enamel, hair keratin and bone collagen) for the giant panda (Ailuropoda melanoleuca), a species derived from meat-eating ancestors. Our results showed that carbon discrimination factor obtained from giant panda tooth enamel (ε 13 C diet-enamel = 10.0‰) and nitrogen discrimination factors from hair keratin (Δ 15 N diet-hair = 2.2‰) and bone collagen (Δ 15 N diet-collagen = 2.3‰) were lower, and carbon discrimination factors from hair keratin (Δ 13 C diet-hair = 5.0‰) and bone collagen (Δ 13 C diet-collagen = 6.1‰) were higher than those of other mammalian carnivores, omnivores and herbivores. Such distinctive values are likely the result of a low-nutrient and specialized bamboo diet, carnivore-like digestive system and exceptionally low metabolism in giant pandas. © 2016 International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and John Wiley & Sons Australia, Ltd.
Anelastic tidal dissipation in multi-layer planets
NASA Astrophysics Data System (ADS)
Remus, F.; Mathis, S.; Zahn, J.-P.; Lainey, V.
2012-09-01
Earth-like planets have anelastic mantles, whereas giant planets may have anelastic cores. As for the fluid parts of a body, the tidal dissipation of such solid regions, gravitationally perturbed by a companion body, highly depends on its internal friction, and thus on its internal structure. Therefore, modelling this kind of interaction presents a high interest to provide constraints on planets interiors, whose properties are still quite uncertain. Here, we examine the equilibrium tide in the solid part of a planet, taking into account the presence of a fluid envelope. We derive the different Love numbers that describe its deformation and discuss the dependence of the quality factor Q on the chosen anelastic model and the size of the core. Taking plausible values for the anelastic parameters, and discussing the frequency-dependence of the solid dissipation, we show how this mechanism may compete with the dissipation in fluid layers, when applied to Jupiter- and Saturn-like planets. We also discuss the case of the icy giants Uranus and Neptune. Finally, we present the way to implement the results in the equations that describe the dynamical evolution of planetary systems.
Depth of a strong jovian jet from a planetary-scale disturbance driven by storms.
Sánchez-Lavega, A; Orton, G S; Hueso, R; García-Melendo, E; Pérez-Hoyos, S; Simon-Miller, A; Rojas, J F; Gómez, J M; Yanamandra-Fisher, P; Fletcher, L; Joels, J; Kemerer, J; Hora, J; Karkoschka, E; de Pater, I; Wong, M H; Marcus, P S; Pinilla-Alonso, N; Carvalho, F; Go, C; Parker, D; Salway, M; Valimberti, M; Wesley, A; Pujic, Z
2008-01-24
The atmospheres of the gas giant planets (Jupiter and Saturn) contain jets that dominate the circulation at visible levels. The power source for these jets (solar radiation, internal heat, or both) and their vertical structure below the upper cloud are major open questions in the atmospheric circulation and meteorology of giant planets. Several observations and in situ measurements found intense winds at a depth of 24 bar, and have been interpreted as supporting an internal heat source. This issue remains controversial, in part because of effects from the local meteorology. Here we report observations and modelling of two plumes in Jupiter's atmosphere that erupted at the same latitude as the strongest jet (23 degrees N). The plumes reached a height of 30 km above the surrounding clouds, moved faster than any other feature (169 m s(-1)), and left in their wake a turbulent planetary-scale disturbance containing red aerosols. On the basis of dynamical modelling, we conclude that the data are consistent only with a wind that extends well below the level where solar radiation is deposited.
Tian, Ge-Ru; Zhao, Guang-Hui; Du, Shuai-Zhi; Hu, Xiong-Feng; Wang, Hui-Bao; Zhang, Long-Xian; Yu, San-Ke
2015-08-01
Enterocytozoon bieneusi is an emerging and opportunistic enteric pathogen triggering diarrhea and enteric disease in humans and animals. Despite extensive research on this pathogen, the prevalence and genotypes of E. bieneusi infection in precious wild animals of giant and red pandas have not been reported. In the present study, 82 faecal specimens were collected from 46 giant pandas (Ailuropoda melanoleuca) and 36 red pandas (Ailurus fulgens) in the northwest of China. By PCR and sequencing of the internal transcribed spacer (ITS) region of the ribosomal RNA (rRNA) gene of E. bieneusi, an overall infection rate of 10.98% (9/82) was observed in pandas, with 8.70% (4/46) for giant pandas, and 13.89% (5/36) for red pandas. Two ITS genotypes were identified: the novel genotype I-like (n=4) and genotype EbpC (n=5). Multilocus sequence typing (MLST) employing three microsatellites (MS1, MS3 and MS7) and one minisatellite (MS4) showed that nine, six, six and nine positive products were amplified and sequenced successfully at four respective loci. A phylogenetic analysis based on a neighbor-joining tree of the ITS gene sequences of E. bieneusi indicated that the genotype EbpC fell into 1d of group 1 of zoonotic potential, and the novel genotype I-like was clustered into group 2. The present study firstly indicated the presence of E. bieneusi in giant and red pandas, and these results suggested that integrated strategies should be implemented to effectively protect pandas and humans from infecting E. bieneusi in China. Copyright © 2015 Elsevier B.V. All rights reserved.
Pimenta, Natalia C; Antunes, André P; Barnett, Adrian A; Macedo, Valêncio W; Shepard, Glenn H
2018-01-01
Commercial hunting for the international trade in animal hides in the 20th century decimated many populations of aquatic wildlife in Amazonia. However, impacts varied significantly between different species and regions, depending upon hunting intensity, accessibility of habitat, and the inherent resilience of various species and their habitats. We investigated the differential responses of two Amazonian Mustelid species, the neotropical otter and giant otter, to commercial hunting pressure along the upper Rio Negro in Brazil, and examined historical factors that influenced spatial and temporal variation in commercial exploitation. We analyzed previously unanalyzed data from historical records of hide shipments to track changes in hide sales and prices for the two species in the late 20th century. We also gathered oral histories from older Baniwa people who had witnessed or participated in commercial otter hunting. These complimentary data sources reveal how intrinsic biological and social characteristics of the two otter species interacted with market forces and regional history. Whereas giant otter populations were driven to local or regional extinction during the late 20th century by commercial hunting, neotropical otters persisted. In recent decades, giant otter populations have returned to some parts of the upper Rio Negro, a development which local people welcome as part of a generalized recovery of the ecosystems in their territory as a result of the banning of animal pelt exports and indigenous land demarcation. This paper expands the scope of the field historical ecology and reflects on the role of local knowledge in biodiversity conservation.
Antunes, André P.; Barnett, Adrian A.; Macedo, Valêncio W.; Shepard, Glenn H.
2018-01-01
Commercial hunting for the international trade in animal hides in the 20th century decimated many populations of aquatic wildlife in Amazonia. However, impacts varied significantly between different species and regions, depending upon hunting intensity, accessibility of habitat, and the inherent resilience of various species and their habitats. We investigated the differential responses of two Amazonian Mustelid species, the neotropical otter and giant otter, to commercial hunting pressure along the upper Rio Negro in Brazil, and examined historical factors that influenced spatial and temporal variation in commercial exploitation. We analyzed previously unanalyzed data from historical records of hide shipments to track changes in hide sales and prices for the two species in the late 20th century. We also gathered oral histories from older Baniwa people who had witnessed or participated in commercial otter hunting. These complimentary data sources reveal how intrinsic biological and social characteristics of the two otter species interacted with market forces and regional history. Whereas giant otter populations were driven to local or regional extinction during the late 20th century by commercial hunting, neotropical otters persisted. In recent decades, giant otter populations have returned to some parts of the upper Rio Negro, a development which local people welcome as part of a generalized recovery of the ecosystems in their territory as a result of the banning of animal pelt exports and indigenous land demarcation. This paper expands the scope of the field historical ecology and reflects on the role of local knowledge in biodiversity conservation. PMID:29601590
Longevity of Compositionally Stratified Layers in Ice Giants
NASA Astrophysics Data System (ADS)
Friedson, A. J.
2017-12-01
In the hydrogen-rich atmospheres of gas giants, a decrease with radius in the mixing ratio of a heavy species (e.g. He, CH4, H2O) has the potential to produce a density stratification that is convectively stable if the heavy species is sufficiently abundant. Formation of stable layers in the interiors of these planets has important implications for their internal structure, chemical mixing, dynamics, and thermal evolution, since vertical transport of heat and constituents in such layers is greatly reduced in comparison to that in convecting layers. Various processes have been suggested for creating compositionally stratified layers. In the interiors of Jupiter and Saturn, these include phase separation of He from metallic hydrogen and dissolution of dense core material into the surrounding metallic-H envelope. Condensation of methane and water has been proposed as a mechanism for producing stable zones in the atmospheres of Saturn and the ice giants. However, if a stably stratified layer is formed adjacent to an active region of convection, it may be susceptible to progressive erosion as the convection intrudes and entrains fluid into the unstable envelope. We discuss the principal factors that control the rate of entrainment and associated erosion and present a specific example concerning the longevity of stable layers formed by condensation of methane and water in Uranus and Neptune. We also consider whether the temporal variability of such layers may engender episodic behavior in the release of the internal heat of these planets. This research is supported by a grant from the NASA Solar System Workings Program.
Hydrogen ion block of the sodium pore in squid giant axons
1983-01-01
The block of squid axon sodium channels by H ions was studied using voltage-clamp and internal perfusion techniques. An increase in the concentration of internal permeant ions decreased the block produced by external H ions. The voltage dependence of the block was found to be nonmonotonic: it was reduced by both large positive and large negative potentials. The ability of internal ions to modify the block by external H+ is explained by a competition among these ions for a binding site within the pore. The nonmonotonic voltage dependence is consistent with this picture if the hydrogen ions are allowed to be permeant. PMID:6315859
VizieR Online Data Catalog: Palomar 5 abundance analysis (Koch+, 2017)
NASA Astrophysics Data System (ADS)
Koch, A.; Code, P.
2017-03-01
The Pal 5 data discussed here were taken as part of a broader program to study the internal dynamics of outer halo GCs (see, e.g., Cote et al., 2002ApJ...574..783C; Jordi et al., 2009AJ....137.4586J; Baumgardt et al., 2009MNRAS.396.2051B; Frank et al., 2012, Cat. J/MNRAS/423/2917). Our Pal 5 target stars were chosen from the red giant branch (RGB) and asymptotic giant branch (AGB) sequences identified in the early photometric studies of Sandage & Hartwick (1977AJ.....82..459S, SH77) and the unpublished photometry and astrometry from Cudworth, Schweitzer, and Majewski (CSM; see Schweitzer et al., 1993, in The Globular Cluster-Galaxy Connection, ASP Conf. Ser., 48, 113). (1 data file).
Liquid Junction and Membrane Potentials of the Squid Giant Axon
Cole, Kenneth S.; Moore, John W.
1960-01-01
The potential differences across the squid giant axon membrane, as measured with a series of microcapillary electrodes filled with concentrations of KCl from 0.03 to 3.0 M or sea water, are consistent with a constant membrane potential and the liquid junction potentials calculated by the Henderson equation. The best value for the mobility of an organic univalent ion, such as isethionate, leads to a probably low, but not impossible, axoplasm specific resistance of 1.2 times sea water and to a liquid junction correction of 4 mv. for microelectrodes filled with 3 M KCl. The errors caused by the assumptions of proportional mixing, unity activity coefficients, and a negligible internal fixed charge cannot be estimated but the results suggest that the cumulative effect of them may not be serious. PMID:13811119
DOE Office of Scientific and Technical Information (OSTI.GOV)
Romanov, N. G., E-mail: nikolai.romanov@mail.ioffe.ru; Tolmachev, D. O.; Gurin, A. S.
2015-06-29
A giant magnetic field effect on spin-dependent recombination of the radiation-induced defects has been found in cerium doped gadolinium based garnet crystals and ceramics, promising materials for scintillator applications. A sharp and strong increase in the afterglow intensity stimulated by external magnetic field and an evidence of the magnetic field memory have been discovered. The effect was ascribed to huge Gd-induced internal magnetic fields, which suppress the recombination, and cross-relaxation with Gd{sup 3+} ions leading to reorientation of the spins of the electron and hole centers. Thus, the spin system of radiation-induced defects in gadolinium garnet based scintillator materials wasmore » shown to accumulate significant energy which can be released in external magnetic fields.« less
Boeing to Rank Colleges by Measuring Graduates' Job Success
ERIC Educational Resources Information Center
Basken, Paul
2008-01-01
Boeing Company, the Chicago-based aerospace giant, has spent the past year matching internal data from employee evaluations with information about the colleges its engineers attended. It has used that analysis to create a ranking system, which it plans to unveil in the coming month, that will show which colleges have produced the workers it…
Space-to-Ground: A Giant Leap: 07/21/2017
2017-07-21
It's been 48 years since humans first walked on the moon. Now NASA is testing its new Orion spacecraft to send crews beyond the moon and bring them back home safely. NASA's Space to Ground is your weekly update on what's happening aboard the International Space Station. Got a question or comment? Use #spacetoground to talk to us.
ERIC Educational Resources Information Center
Hoppers, Catherine A. Odora
2009-01-01
As the world settles in to the reality of globalization, it becomes clear that many incongruous facets of human existence have been forced together into a giant tumbler--economy, information systems, finance and people--giving rise to contradictory but also generative responses. Previously excluded and excised "objects" are now occupying intimate…
Waking a Sleeping Giant: The Tobacco Industry’s Response to the Polonium-210 Issue
Muggli, Monique E.; Ebbert, Jon O.; Robertson, Channing; Hurt, Richard D.
2008-01-01
The major tobacco manufacturers discovered that polonium was part of tobacco and tobacco smoke more than 40 years ago and attempted, but failed, to remove this radioactive substance from their products. Internal tobacco industry documents reveal that the companies suppressed publication of their own internal research to avoid heightening the public’s awareness of radioactivity in cigarettes. Tobacco companies continue to minimize their knowledge about polonium-210 in cigarettes in smoking and health litigation. Cigarette packs should carry a radiation-exposure warning label. PMID:18633078
Intraoperative Computed Tomography (CT) for Treating Giant Carotid Intracavernous Aneurysms
Xue, Zhe; Wang, Fuyu; Sun, Zhenghui; Zhang, Hui; Wu, Chen; Kong, Dongsheng; Xu, Bainan
2017-01-01
Background Giant carotid intracavernous aneurysm refers to those lesions larger than 2.5 cm and derived from a cavernous segment, accounting for about 30% of all intracranial tumors. Dynamic CT perfusion imaging (PCT) is a common method recently employed to evaluate cerebral perfusion. This study investigated the efficacy and clinical application of intraoperative CT in the surgery for giant symptomatic carotid intracavernous aneurysm. Material/Methods A retrospective analysis was performed on 23 cases with giant symptomatic carotid intracavernous aneurysm. BTO testing was performed before surgery. Differential treatments were performed based on the condition of aneurysm, and some patients received intraoperative PCT. Postoperative anti-coagulation was given with DSA or CTA follow-up examinations at 3–6 months, 1 year, and 2 years after surgery. Results A total of 17 patients received aneurysm isolation coupled with high-flow bypass surgery. Among those, 9 developed early-onset neurological function after surgery, with gradual recover within 6 months. One coma patient died 25 months after discharge. One patient had aneurysm isolation with clapping of anterior communicating artery, and the other 5 cases received artery clapping only. In those patients, 4 had improvement at early phase, while 1 patient had numbness of the oculomotor nerve. Six patients received surgery in the CT room, including 5 cases with single proximal ligation of the internal carotid artery plus 1 aneurysm isolation combined with high-flow bypass surgery. Conclusions Intraoperative PCT can provide objective evidence and effective evaluation of cerebral perfusion. PMID:28640793
How rheological heterogeneities control the internal deformation of salt giants.
NASA Astrophysics Data System (ADS)
Raith, Alexander; Urai, Janos L.
2017-04-01
Salt giants, like the North European Zechstein, consist of several evaporation cycles of different evaporites with highly diverse rheologies. Common Potassium and Magnesium (K-Mg) salt are typically 10 to 100 times less viscous as halite while stringers consisting of anhydrite and carbonates are about 100 times more viscous. In most parts, these mechanically layered bodies experienced complex deformation, resulting in large scale internal folding with ruptured stringers and shear zones, as observed in seismic images. Furthermore, locally varying evaporation history produced different mechanical stratigraphies across the salt basin. Although most of these extraordinary soft or strong layers are rather thin (<100 m) compared to the dominating halite, we propose they have first order control on the deformation and the resulting structures inside salt bodies. Numerical models representing different mechanical stratigraphies of hard and soft layers inside a salt body were performed to analyze their influence on the internal deformation during lateral salt flow. The results show that a continuous or fractured stringer is folded and thrusted during salt contraction while soft K-Mg salt layers act as internal décollement. Depending on the viscosity of the fractured stringers, the shortening is mostly compensated by either folding or thrusting. This folding has large control over the internal structure of the salt body imposing a dominating wavelength to the whole structure during early deformation. Beside strong stringers, K-Mg salt layers also influence the deformation and salt flow inside the salt pillow. Strain is accumulated in the soft layers leading to stronger salt flow near these layers and extensive deformation inside of them. Thus, if a soft layer is present near a stringer, it will experience more deformation. Additionally, the strong strain concentration in the soft layers could decouple parts of the salt body from the main deformation.
The origin of CO in the stratosphere of Uranus
NASA Astrophysics Data System (ADS)
Cavalié, Thibault; Moreno, R.; Lellouch, E.; Hartogh, P.; Venot, O.; Orton, G. S.; Jarchow, C.; Encrenaz, T.; Selsis, F.; Hersant, F.; Fletcher, L. N.
2013-10-01
Oxygen-rich deep interiors of the Giant Planets cannot explain the discovery of H2O and CO2 in the stratospheres of the Giant Planets by Feuchtgruber et al. (1997) because these species are trapped by condensation around their tropopause levels (except CO2 in Jupiter and Saturn). Therefore, several sources in the direct or far environment of the Giant Planets have been proposed: icy rings and/or satellites, interplanetary dust particles and large comet impacts. CO does not condense at the tropopauses of Giant Planets, so that oxygen-rich interiors are a valid source. An internal component has indeed been observed in the vertical profile of CO in Jupiter (Bézard et al., 2002) and in Neptune (Lellouch et al., 2005), while an upper limit has been set on its magnitude by for Saturn (Cavalié et al., 2009). In addition to interiors, large comets seem to be the dominant external source, as shown by various studies: Bézard et al. (2002) for Jupiter, Cavalié et al. (2010) for Saturn and Lellouch et al. (2005) for Neptune. The first detection of CO in Uranus was obtained by Encrenaz et al. (2004) from fluorescent emission at 4.7 microns. Assuming a uniform distribution, a mixing ratio of 2x10-8 was derived. Despite this first detection almost a decade ago, the situation has remained unclear ever since. In this paper, we will present the first submillimeter detection of CO in Uranus, carried out with Herschel in 2011-2012. Using a simple diffusion model, we review the various possible sources of CO (internal and external). We show that CO is mostly external. We also derive an upper limit for the internal source. And with the thermochemical model of Venot et al. (2012), adapted to the interior of Uranus, we derive an upper limit on its deep O/H ratio from it. Acknowledgments T. Cavalié acknowledges support from CNES and the European Research Council (Starting Grant 209622: E3ARTHs). References Bézard et al., 2002. Icarus, 159, 95-111. Cavalié et al., 2009. Icarus, 203, 531-540. Cavalié et al., 2010. A&A, 510, A88. Encrenaz et al., 2004. A&A, 413, L5-L9. Feuchtgruber et al., 1997. Nature, 389, 159-162. Lellouch et al., 2005. A&A, 430, L37-L40. Venot et al., 2012. A&A, 546, A43.
The Fuzziness of Giant Planets’ Cores
DOE Office of Scientific and Technical Information (OSTI.GOV)
Helled, Ravit; Stevenson, David
2017-05-01
Giant planets are thought to have cores in their deep interiors, and the division into a heavy-element core and hydrogen–helium envelope is applied in both formation and structure models. We show that the primordial internal structure depends on the planetary growth rate, in particular, the ratio of heavy elements accretion to gas accretion. For a wide range of likely conditions, this ratio is in one-to-one correspondence with the resulting post-accretion profile of heavy elements within the planet. This flux ratio depends sensitively on the assumed solid-surface density in the surrounding nebula. We suggest that giant planets’ cores might not bemore » distinct from the envelope and includes some hydrogen and helium, and the deep interior can have a gradual heavy-element structure. Accordingly, Jupiter’s core may not be well defined. Accurate measurements of Jupiter’s gravitational field by Juno could put constraints on Jupiter’s core mass. However, as we suggest here, the definition of Jupiter’s core is complex, and the core’s physical properties (mass, density) depend on the actual definition of the core and on the planet’s growth history.« less
Multi-periodic pulsations of a stripped red-giant star in an eclipsing binary system.
Maxted, Pierre F L; Serenelli, Aldo M; Miglio, Andrea; Marsh, Thomas R; Heber, Ulrich; Dhillon, Vikram S; Littlefair, Stuart; Copperwheat, Chris; Smalley, Barry; Breedt, Elmé; Schaffenroth, Veronika
2013-06-27
Low-mass white-dwarf stars are the remnants of disrupted red-giant stars in binary millisecond pulsars and other exotic binary star systems. Some low-mass white dwarfs cool rapidly, whereas others stay bright for millions of years because of stable fusion in thick surface hydrogen layers. This dichotomy is not well understood, so the potential use of low-mass white dwarfs as independent clocks with which to test the spin-down ages of pulsars or as probes of the extreme environments in which low-mass white dwarfs form cannot fully be exploited. Here we report precise mass and radius measurements for the precursor to a low-mass white dwarf. We find that only models in which this disrupted red-giant star has a thick hydrogen envelope can match the strong constraints provided by our data. Very cool low-mass white dwarfs must therefore have lost their thick hydrogen envelopes by irradiation from pulsar companions or by episodes of unstable hydrogen fusion (shell flashes). We also find that this low-mass white-dwarf precursor is a type of pulsating star not hitherto seen. The observed pulsation frequencies are sensitive to internal processes that determine whether this star will undergo shell flashes.
In Situ Probe Science at Saturn
NASA Technical Reports Server (NTRS)
Atkinson, D.H.; Lunine, J.I.; Simon-Miller, A. A.; Atreya, S. K.; Brinckerhoff, W.; Colaprete, A.; Coustenis, A.; Fletcher, L. N.; Guillot, T.; Lebreton, J.-P.;
2014-01-01
A fundamental goal of solar system exploration is to understand the origin of the solar sys-tem, the initial stages, conditions, and processes by which the solar system formed, how the formation pro-cess was initiated, and the nature of the interstellar seed material from which the solar system was born. Key to understanding solar system formation and subsequent dynamical and chemical evolution is the origin and evolution of the giant planets and their atmospheres. Several theories have been put forward to explain the process of solar system formation, and the origin and evolution of the giant planets and their atmospheres. Each theory offers quantifiable predictions of the abundances of noble gases He, Ne, Ar, Kr, and Xe, and abundances of key isotopic ratios 4He3He, DH, 15N14N, 18O16O, and 13C12C. Detection of certain dis-equilibrium species, diagnostic of deeper internal pro-cesses and dynamics of the atmosphere, would also help discriminate between competing theories. Measurements of the critical abundance profiles of these key constituents into the deeper well-mixed at-mosphere must be complemented by measurements of the profiles of atmospheric structure and dynamics at high vertical resolution and also require in situ explora-tion. The atmospheres of the giant planets can also serve as laboratories to better understand the atmospheric chem-istries, dynamics, processes, and climates on all planets including Earth, and offer a context and provide a ground truth for exoplanets and exoplanetary systems. Additionally, Giant planets have long been thought to play a critical role in the development of potentially habitable planetary systems. In the context of giant planet science provided by the Galileo, Juno, and Cassini missions to Jupiter and Sat-urn, a small, relatively shallow Saturn probe capable of measuring abundances and isotopic ratios of key at-mospheric constituents, and atmospheric structure in-cluding pressures, temperatures, dynamics, and cloud locations and properties not accessible by remote sens-ing can serve to test competing theories of solar system and giant planet origin, chemical, and dynamical evolution.
Examination of the solution behaviors of the giant inorganic-organic amphiphilic hybrids
NASA Astrophysics Data System (ADS)
Zhang, Baofang
Presently, the self-assembly behaviors of traditional small surfactants and amphiphilic block copolymers are fairly well understood. In comparison, rather little is known about the self-assembly behaviors of the giant inorganic-organic amphiphilic hybrids in solution. It remains a wide open field to explore. Giant inorganic-organic amphiphilic hybrids, consisting of nanoscale inorganic clusters and organic functional groups, represent a novel class of functional hybrid materials. They have unique physical and chemical properties and potential applications in catalysis, electronic, optics, magnetic materials, medicine and biology. Therefore, as emerging building blocks, they have promising prospects in the advanced materials. In this PhD work, several representative giant inorganic-organic amphiphilic hybrids (triangular-shaped polyoxometalate (POM)-containing inorganic/organic amphiphilic hybrids, POM-containing fluorosurfactants hybrids, POM-containing peptide hybrids POM-peptide hybrids and polyhedral oligometric silsesquioxane (POSS)-polystyrene (PS) are chosen for studying their self-assembly behaviors in solution. Based on the knowledge of the physical chemistry, colloid and polymer science, we focus on the mechanism of the self-assembly process, and the morphology control of the supramolecular structures through the internal and external conditions, such as the composition of the giant amphiphilies, molecular architectures, solvent nature, temperature, concentration, and extrally added salts. It is found that the counterion-meditated interactions dominate the self-assembly of triangular-shaped hybrids in acetone/water mixed solutions, due to the highly dominant hydrophilic portions; the solvent-swelling effect, instead of the charge effect, dominates the whole self-assembly process of the POM-containing fluorosurfactants; the analogy between small surfactants and giant amphiphiles POSS-PS allows a rough assessment of the possible morphologies of the supramolecular structures, and the particular values of the molecular packing parameter can be translated via simple geometrical relations into specific shape of the equilibrium supramolecular structures. For the experiments, laser light scattering (LLS) technique is used to monitor the entire self-assembly processes. The morphology and size of the supramolecular structures are determined by using dynamic light scattering (DLS) and static light scattering (SLS). Electron microscopies (TEM, SEM and AFM) are used to confirm the assembly structures and size. The stability of the assembly solution system is characterized by zeta potential.
Neptune Polar Orbiter with Probes
NASA Technical Reports Server (NTRS)
Bienstock, Bernard; Atkinson, David; Baines, Kevin; Mahaffy, Paul; Steffes, Paul; Atreya, Sushil; Stern, Alan; Wright, Michael; Willenberg, Harvey; Smith, David;
2005-01-01
The giant planets of the outer solar system divide into two distinct classes: the gas giants Jupiter and Saturn, which consist mainly of hydrogen and helium; and the ice giants Uranus and Neptune, which are believed to contain significant amounts of the heavier elements oxygen, nitrogen, and carbon and sulfur. Detailed comparisons of the internal structures and compositions of the gas giants with those of the ice giants will yield valuable insights into the processes that formed the solar system and, perhaps, other planetary systems. By 2012, Galileo, Cassini and possibly a Jupiter Orbiter mission with microwave radiometers, Juno, in the New Frontiers program, will have yielded significant information on the chemical and physical properties of Jupiter and Saturn. A Neptune Orbiter with Probes (NOP) mission would deliver the corresponding key data for an ice giant planet. Such a mission would ideally study the deep Neptune atmosphere to pressures approaching and possibly exceeding 1000 bars, as well as the rings, Triton, Nereid, and Neptune s other icy satellites. A potential source of power would be nuclear electric propulsion (NEP). Such an ambitious mission requires that a number of technical issues be investigated, however, including: (1) atmospheric entry probe thermal protection system (TPS) design, (2) probe structural design including seals, windows, penetrations and pressure vessel, (3) digital, RF subsystem, and overall communication link design for long term operation in the very extreme environment of Neptune's deep atmosphere, (4) trajectory design allowing probe release on a trajectory to impact Neptune while allowing the spacecraft to achieve a polar orbit of Neptune, (5) and finally the suite of science instruments enabled by the probe technology to explore the depths of the Neptune atmosphere. Another driving factor in the design of the Orbiter and Probes is the necessity to maintain a fully operational flight system during the lengthy transit time from launch through Neptune encounter, and throughout the mission. Following our response to the recent NASA Research Announcement (NRA) for Space Science Vision Missions for mission studies by NASA for implementation in the 2013 or later time frame, our team has been selected to explore the feasibility of such a Neptune mission.
International Conference on Nanoscience - Young Giants of Nanoscience, 2016
2017-10-12
Nanoelectronics • Nanoptics • Catalysis • Sense and Response Systems • Energy Conversion and Storage • Stimuli-responsive materials • Molecular motors...This issue will address the following topics: advanced nanointerfaces research in energy , medicine, optics, flexible electronics and nanofabrication...Methods • Nanomedicine • Nanoelectronics • Nanoptics • Catalysis • Sense and Response Systems • Energy Conversion and Storage • Stimuli
The Internal Energy for Molecular Hydrogen in Gravitationally Unstable Protoplanetary Disks
NASA Astrophysics Data System (ADS)
Boley, Aaron C.; Hartquist, Thomas W.; Durisen, Richard H.; Michael, Scott
2007-02-01
The gas equation of state may be one of the critical factors for the disk instability theory of gas giant planet formation. This Letter addresses the treatment of H2 in hydrodynamic simulations of gravitationally unstable disks. In our discussion, we point out possible consequences of erroneous specific internal energy relations, approximate specific internal energy relations with discontinuities, and assumptions of constant Γ1. In addition, we consider whether the ortho/para ratio for H 2 in protoplanetary disks should be treated dynamically as if the species are in equilibrium. Preliminary simulations indicate that the correct treatment is particularly critical for the study of gravitational instability when T=30-50 K.
How tides get dissipated in Saturn? A question probably answerable by Cassni
NASA Astrophysics Data System (ADS)
Luan, Jing
2017-06-01
Tidal dissipation inside a giant planet is important in understanding the orbital evolutions of its natural satellites and perhaps some of the extrasolar giant planets. The tidal dissipation is conventionally parameterized by the tidal quality factor, Q. The corresponding tidal torque declines rapidly with distance adopting constant Q. However, the current fast migration rates of some Saturnian satellites reported by Lainey et al. (2015) conflict this conventional conceptual belief. Alternatively, resonance lock between a satellite and an internal oscillation mode or wave of Saturn, proposed by Fuller et al. (2016), could naturally match the observational migration rates. However, the question still remains to be answered what type of mode or wave is locked with each satellite. There are two candidates for resonance lock, one is gravity mode, and the other is inertial wave attractor. They generate very different gravity acceleration anomaly near the surface of Saturn, which may be distinguishable by the data to be collected by Cassini during its proximal orbits between April and September, 2017. Indicative information about the interior of Saturn may be extracted since the existence of both gravity mode and inertial wave attractor depends on the internal structure of Saturn.
Equation of State and Electrical Conductivity of Helium at High Pressures and Temperatures
NASA Astrophysics Data System (ADS)
McWilliams, R. S.; Eggert, J. H.; Loubeyre, P.; Brygoo, S.; Collins, G.; Jeanloz, R.
2004-12-01
Helium, the second-most abundant element in the universe and giant planets, is expected to metallize at much higher pressures and temperatures than the most abundant element, hydrogen. The difference in chemical-bonding character, between insulator and metal, is expected to make hydrogen-helium mixtures immiscible throughout large fractions of planetary interiors, and therefore subject to gravitational separation contributing significantly to the internal dynamics of giant planets. Using laser-driven shock waves on samples pre-compressed in high-pressure cells, we have obtained the first measurements of optical reflectivity from the shock front in helium to pressures of 146 GPa. The reflectivity exceeds 5% above \\ensuremath{\\sim} 100 GPa, indicating high electrical conductivity. By varying the initial pressure (hence density) of the sample, we can access a much wider range of final pressure-temperature conditions than is possible in conventional Hugoniot experiments. Our work increases by nine-fold the pressure range of single-shock measurements, in comparison with gas-gun experiments, and yields results in agreement with the Saumon, Chabrier and Van Horn (1994) equation of state for helium. This changes the internal structures inferred for Jupiter-size planets, relative to models based on earlier equations of state (e. g., SESAME).
Infection cycles of large DNA viruses: Emerging themes and underlying questions
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mutsafi, Yael, E-mail: yael.mutsafi@weizmann.ac.il; Fridmann-Sirkis, Yael; Milrot, Elad
The discovery of giant DNA viruses and the recent realization that such viruses are diverse and abundant blurred the distinction between viruses and cells. These findings elicited lively debates on the nature and origin of viruses as well as on their potential roles in the evolution of cells. The following essay is, however, concerned with new insights into fundamental structural and physical aspects of viral replication that were derived from studies conducted on large DNA viruses. Specifically, the entirely cytoplasmic replication cycles of Mimivirus and Vaccinia are discussed in light of the highly limited trafficking of large macromolecules in themore » crowded cytoplasm of cells. The extensive spatiotemporal order revealed by cytoplasmic viral factories is described and contended to play an important role in promoting the efficiency of these ‘nuclear-like’ organelles. Generation of single-layered internal membrane sheets in Mimivirus and Vaccinia, which proceeds through a novel membrane biogenesis mechanism that enables continuous supply of lipids, is highlighted as an intriguing case study of self-assembly. Mimivirus genome encapsidation was shown to occur through a portal different from the ‘stargate’ portal that is used for genome release. Such a ‘division of labor’ is proposed to enhance the efficacy of translocation processes of very large viral genomes. Finally, open questions concerning the infection cycles of giant viruses to which future studies are likely to provide novel and exciting answers are discussed. - Highlights: • The discovery of giant DNA viruses blurs the distinction between viruses and cells. • Mimivirus and Vaccinia replicate exclusively in their host cytoplasm. • Mimivirus genome is delivered through a unique portal coined the Stargate. • Generation of Mimivirus internal membrane proceeds through a novel pathway.« less
Collaborative observations of HDE 332077
NASA Technical Reports Server (NTRS)
Ake, Thomas B., III
1995-01-01
IUE low dispersion observations were made of the T(sub c)-deficient peculiar red giant (PRG) star, HDE 332077, to test the hypothesis that T(sub c)-poor PRG's are formed as a result of mass transfer from a binary companion rather than from internal thermal pulsing while on the asymptotic red giant branch. Previous ground-based observations of this star indicated that it is a binary, but the secondary star was too massive for an expected white dwarf. A deep, short wavelength prime (SWP) exposure was needed to search for evidence of an A-type main-sequence companion. We obtained a 120 minute LWP exposure (LWP 23479), followed by a collaborative 1230 minute SWP exposure (SWP 45113). These observations were combined with our earlier IUE and optical data on this PRG star to model the spectral energy distribution of the system.
TRANSVERSE ELECTRIC IMPEDANCE OF THE SQUID GIANT AXON
Curtis, Howard J.; Cole, Kenneth S.
1938-01-01
The impedance of the excised giant axon from hindmost stellar nerve of Loligo pealii has been measured over the frequency range from 1 to 2500 kilocycles per second. The measurements have been made with the current flow perpendicular to the axis of the axon to permit a relatively simple analysis of the data. It has been found that the axon membrane has a polarization impedance with an average phase angle of 76° and an average capacity of 1.1µf./cm2 at 1 kilocycle. The direct current resistance of the membrane could not be measured, but was greater than 3 ohm cm.2 and the average internal specific resistance was four times that of sea water. There was no detectable change in the membrane impedance when the axon lost excitability, but some time later it decreased to zero. PMID:19873081
Core to Atmosphere Exploration of Ice Giants: A Uranus Mission Concept Study
NASA Astrophysics Data System (ADS)
Jensema, R. J.; Arias-Young, T. M.; Wilkins, A. N.; Ermakov, A.; Bennett, C.; Dietrich, A.; Hemingway, D.; Klein, V.; Mane, P.; Marr, K. D.; Masterson, J.; Siegel, V.; Stober, K. J.; Talpe, M.; Vines, S. K.; Wetteland, C. J.
2014-12-01
Ice giants remain largely unexplored, as their large distance from the Sun limits both Earth-based observations and spacecraft visits. The significant occurrence of ice giant-sized planets among detected exoplanets presents an impetus to study Uranus to understand planetary formation, dynamics, and evolution. In addition, Uranus is also uniquely interesting, given the large inclination of its rotation axis and magnetospheric configuration. In this work, we design a mission concept that aims to maximize scientific return by measuring Uranus' chemical composition, internal structure, and magnetosphere, the first two being primary indicators of ice giant formation mechanisms. For this study, we analyze the trade space for a Uranus mission constrained by a cost cap of $1B. We discuss the decision making processes behind our choices of the science priorities, instrument suite and orbital configuration. Trade space decisions include a strong onboard instrument suite in lieu of a descent probe, an orbiter instead of a flyby mission, and design constraints on the power and propulsion systems. The mission, CAELUS (Core and Atmospheric Evolution Laboratory for Uranus Science), is designed for an August 2023 launch. Following a 14-year cruise with multiple planetary gravity assists, the spacecraft would begin its science mission, which consists of a series of ten 30-day near-polar orbits around Uranus. The instrument suite would consist of a microwave radiometer, Doppler seismometer, magnetometer, and UV spectrometer. These four instruments, along with a high-gain antenna capable of gravity science, would provide a comprehensive science return that meets the bulk of the scientific objectives of the 2013 NRC Planetary Science Decadal Survey for ice giants, most notably those regarding the chemical composition, interior structure, and dynamo of Uranus. This mission concept was created as part of an educational exercise for the 2014 Planetary Science Summer School at the Jet Propulsion Laboratory.
Giant Radio Flare of Cygnus X-3 in September 2016
NASA Astrophysics Data System (ADS)
Trushkin, S. A.; Nizhelskij, N. A.; Tsybulev, P. G.; Zhekanis, G. V.
2017-06-01
In the long-term multi-frequency monitoring program of the microquasars with RATAN-600 we discovered the giant flare from X-ray binary Cyg X-3 on 13 September 2016. It happened after 2000 days of the 'quiescent state' of the source passed after the former giant flare (˜18 Jy) in March 2011. We have found that during this quiet period the hard X-ray flux (Swift/BAT, 15-50 keV) and radio flux (RATAN-600, 11 GHz) have been strongly anti-correlated. Both radio flares occurred after transitions of the microquasar to a 'hypersoft' X-ray state that occurred in February 2011 and in the end of August 2016. The giant flare was predicted by us in the first ATel (Trushkin et al. (2016)). Indeed after dramatic decrease of the hard X-ray Swift 15-50 keV flux and RATAN 4- 11 GHz fluxes (a 'quenched state') a small flare (0.7 Jy at 4-11 GHz) developed on MJD 57632 and then on MJD 57644.5 almost simultaneously with X-rays radio flux rose from 0.01 to 15 Jy at 4.6 GHz during few days. The rise of the flaring flux is well fitted by a exponential law that could be a initial phase of the relativistic electrons generation by internal shock waves in the jets. Initially spectra were optically thick at frequencies lower 2 GHz and optically thin at frequencies higher 8 GHz with typical spectral index about -0.5. After maximum of the flare radio fluxes at all frequencies faded out with exponential law.
Urticaria and periorbital edema as prodromal presenting signs of acute hepatitis B infection.
van Aalsburg, Rob; de Pagter, Anne P J; van Genderen, Perry J
2011-01-01
A 34-year-old patient presented with giant, transient urticarial skin lesions and periorbital edema after a 3-month stay in DR Congo. Retrospective analysis of stored samples revealed that these signs were prodromal manifestations of acute hepatitis B infection. The hepatitis B infection was spontaneously cleared; the skin lesion did not recur. © 2011 International Society of Travel Medicine.
Russian Energy Policy Toward Neighboring Countries
2010-03-22
countries, Russian energy firms are able to manipulate the internal political situation by favoring certain local businessmen and politicians...Russia is even more significant. It is the single largest contributor to the Russian government’s budget, providing about 25% of tax receipts. It...policy changed in 2003, when Mikhail Khodorkovsky, head of the giant Yukos oil firm, was arrested on tax evasion and other charges. However, most
Vk, Varsha; Hallikeri, Kaveri; Girish, H C; Murgod, Sanjay
2014-01-01
Central and Peripheral giant cell granulomas of jaws are uncommon, benign, reactive disorders that are characterized by the presence of numerous multinucleated giant cells and mononuclear cells within a stroma. The origin of the multinucleated giant cells is controversial; probably originating from fusion of histiocytes, endothelial cells and fibroblasts. To assess the expression of CD34 and CD68 in central and peripheral giant cell granulomas to understand the origin of these multinucleated giant cells. Twenty cases of Central and Peripheral giant cell granulomas were evaluated immunohistochemically for CD34 and CD68 proteins expression. Immunopositivity for CD34 was seen only in cytoplasm of endothelial cells of blood vessels; whereas, consistent cytoplasmic immunopositivity for CD68 was seen in few stromal cells. Statistical significance was seen in mean number of multinucleated giant cells, mean number of nuclei in multinucleated giant cells, CD68 expression and ratio of macrophages to multinucleated giant cells among two lesions. Although the central giant cell granulomas share some clinical and histopathological similarities with peripheral giant cell granulomas, differences in mean number of nuclei in multinucleated giant cells and CD68 immunoreactivity may underlie the distinct clinical behavior.
Active Transport of Potassium by the Giant Neuron of the Aplysia Abdominal Ganglion
Russell, J. M.; Brown, A. M.
1972-01-01
We measured the internal potassium activity, ai K, and membrane potential, Em, simultaneously in 111 R2 giant neurons of Aplysia californica. ai K was 165.3 ± 3.4 mM, Em was -47.8 ± 0.9 mv, and E K calculated using the Nernst equation was -76.9 ± 0.05 mv. Such values were maintained for as long as 6 hr of continuous recording in untreated cells, ai K fell exponentially after the following treatments: cooling to 0.5°–4°C, ouabain, zero external potassium, 2,4-dinitrophenol, and cyanide. The effects of cooling and zero potassium were reversible. Potassium permeability was calculated from net potassium flux using the constant field equation and ranged from 2.6 to 18.5 x 10-8 cm/sec. We conclude that potassium is actively transported into this neuron against a 30–40 mv electrochemical gradient. PMID:4644326
Long Duration Responses in Squid Giant Axons Injected with 134Cesium Sulfate Solutions
Sjodin, R. A.
1966-01-01
Giant axons from the squid were injected with 1.5 M cesium sulfate solutions containing the radioactive isotopes 42K and 134Cs. These axons, when stimulated, gave characteristic long duration action potentials lasting between 5 and 45 msec. The effluxes of 42K and 134Cs were measured both under resting conditions and during periods of repetitive stimulation. During the lengthened responses there were considerable increases in potassium efflux but only small increases in cesium efflux. The selectivity of the delayed rectification process was about 9 times greater for potassium ions than for cesium ions. The data suggest that internal cesium ions inhibit the outward potassium movement occurring during an action potential. The extra potassium effluxes taking place during excitation appear to be reduced in the presence of cesium ions to values between 7 and 22% of those expected in the absence of cesium inhibition. PMID:11526828
Ohmic Inflation of Hot Jupiters: an Analytical Approach
NASA Astrophysics Data System (ADS)
Ginzburg, Sivan; Sari, Re'em
2015-12-01
Many giant exoplanets in close orbits have observed radii which exceed theoretical predictions.One suggested explanation for this discrepancy is heat deposited deep inside the atmospheres of these hot Jupiters.We present an analytical model for the evolution of such irradiated, and internally heated gas giants, and derive scaling laws for their cooling rates and radii.We estimate the Ohmic dissipation resulting from the interaction between the atmospheric winds and the planet's magnetic field, and apply our model to Ohmically heated planets.Our model can account for the observed radii of many inflated planets, but not the most extreme ones.We show that Ohmically heated planets have already reached their equilibrium phase and they no longer contract.We show that it is possible to re-inflate planets, but we confirm that re-heating timescales are longer by about a factor of 30 than cooling times.
Adhesion of CdTe quantum dots on model membranes and internalization into RBL-2H3 cells.
Zhang, Mengmeng; Wei, Xiaoran; Ding, Lei; Hu, Jingtian; Jiang, Wei
2017-06-01
Quantum dots (QDs) have attracted broad attention due to their special optical properties and promising prospect in medical and biological applications. However, the process of QDs on cell membrane is worth further investigations because such process may lead to harmful effects on organisms and also important for QD application. In this study, adhesion of amino- and carboxyl-coated CdTe QDs (A-QDs and C-QDs) on cell membrane and the subsequent internalization are studied using a series of endocytosis-free model membranes, including giant and small unilamellar vesicles, supported lipid bilayers and giant plasma membrane vesicles (GPMVs). The adhered QD amounts on model membranes are quantified by a quartz crystal microbalance. The CdTe QD adhesion on model membranes is governed by electrostatic forces. Positively charged A-QDs adhere on GPMV surface and passively penetrate the plasma membrane via endocytosis-free mechanism, but negatively charged C-QDs cannot. Rat basophilic leukemia (RBL-2H3) cells are exposed to CdTe QDs to monitor the QD internalization process. Both A- and C-QDs are internalized by RBL-2H3 cells mainly via endocytosis. CdTe QDs do not accumulate on the plasma membrane of living cells due to the fast endocytosis and the weakened electrostatic attraction in biological medium, resulting in low chance of passive penetration. The suspended cells after trypsin digestion take more QDs than the adherent cells. A-QDs cause lower cell viability than C-QDs, probably because the approach of positively charged QDs to cells is favored and the smaller aggregates of A-QDs. Copyright © 2017 Elsevier Ltd. All rights reserved.
A biomineralization study of the Indo-Pacific giant clam Tridacna gigas
NASA Astrophysics Data System (ADS)
Gannon, M. E.; Pérez-Huerta, A.; Aharon, P.; Street, S. C.
2017-06-01
The giant clam, Tridacna gigas, is an important faunal component of reef ecosystems of the Indo-Pacific region. In addition to its ecological role, shells of this bivalve species are useful bioarchives for past climate and environmental reconstructions. However, the biomineralization processes involved in shell aragonite deposition are insufficiently understood. Here, we present a study of the shell microstructure of modern specimens from Palm Island, Great Barrier Reef (GBR), Australia, and Huon Peninsula, Papua New Guinea (PNG), using a combination of petrography, scanning electron microscopy, electron backscatter diffraction, Raman spectroscopy and stable carbon isotope ratios. Daily growth increments were recognizable in all specimens through ontogeny, and counting these growth lines provides a robust specimen age estimate. For the internal layers, paired increments of organized aragonitic needles and compact, oblong crystals were recognized in a specimen from PNG, whereas specimens from GBR were composed of shield-like crystals that were not definable at the microscale. The combination of nutrient availability, rainfall and solar irradiance are likely to be the most significant factors controlling shell growth and may explain the observed differences in microstructure. The external layer, identical in all specimens, was composed of dendritic microstructure that is significantly enriched in 13C compared to the internal layer, suggesting different metabolic controls on layer deposition. We propose that the mineralization of the internal and external layers is independent from each other and associated with the activity of specific mantles. Future studies using T. gigas shells as bioarchives should consider the microstructure as it reflects the environment in which the individual lived and the differences in mineralization pathways of internal and external layers.
Cunningham, J A; Thomas, C-W; Bengtson, S; Marone, F; Stampanoni, M; Turner, F R; Bailey, J V; Raff, R A; Raff, E C; Donoghue, P C J
2012-05-07
The Ediacaran Doushantuo biota has yielded fossils interpreted as eukaryotic organisms, either animal embryos or eukaryotes basal or distantly related to Metazoa. However, the fossils have been interpreted alternatively as giant sulphur bacteria similar to the extant Thiomargarita. To test this hypothesis, living and decayed Thiomargarita were compared with Doushantuo fossils and experimental taphonomic pathways were compared with modern embryos. In the fossils, as in eukaryotic cells, subcellular structures are distributed throughout cell volume; in Thiomargarita, a central vacuole encompasses approximately 98 per cent cell volume. Key features of the fossils, including putative lipid vesicles and nuclei, complex envelope ornament, and ornate outer vesicles are incompatible with living and decay morphologies observed in Thiomargarita. Microbial taphonomy of Thiomargarita also differed from that of embryos. Embryo tissues can be consumed and replaced by bacteria, forming a replica composed of a three-dimensional biofilm, a stable fabric for potential fossilization. Vacuolated Thiomargarita cells collapse easily and do not provide an internal substrate for bacteria. The findings do not support the hypothesis that giant sulphur bacteria are an appropriate interpretative model for the embryo-like Doushantuo fossils. However, sulphur bacteria may have mediated fossil mineralization and may provide a potential bacterial analogue for other macroscopic Precambrian remains.
Cunningham, J. A.; Thomas, C.-W.; Bengtson, S.; Marone, F.; Stampanoni, M.; Turner, F. R.; Bailey, J. V.; Raff, R. A.; Raff, E. C.; Donoghue, P. C. J.
2012-01-01
The Ediacaran Doushantuo biota has yielded fossils interpreted as eukaryotic organisms, either animal embryos or eukaryotes basal or distantly related to Metazoa. However, the fossils have been interpreted alternatively as giant sulphur bacteria similar to the extant Thiomargarita. To test this hypothesis, living and decayed Thiomargarita were compared with Doushantuo fossils and experimental taphonomic pathways were compared with modern embryos. In the fossils, as in eukaryotic cells, subcellular structures are distributed throughout cell volume; in Thiomargarita, a central vacuole encompasses approximately 98 per cent cell volume. Key features of the fossils, including putative lipid vesicles and nuclei, complex envelope ornament, and ornate outer vesicles are incompatible with living and decay morphologies observed in Thiomargarita. Microbial taphonomy of Thiomargarita also differed from that of embryos. Embryo tissues can be consumed and replaced by bacteria, forming a replica composed of a three-dimensional biofilm, a stable fabric for potential fossilization. Vacuolated Thiomargarita cells collapse easily and do not provide an internal substrate for bacteria. The findings do not support the hypothesis that giant sulphur bacteria are an appropriate interpretative model for the embryo-like Doushantuo fossils. However, sulphur bacteria may have mediated fossil mineralization and may provide a potential bacterial analogue for other macroscopic Precambrian remains. PMID:22158954
NASA Astrophysics Data System (ADS)
Khan, Saniya; Hall, Oliver J.; Miglio, Andrea; Davies, Guy R.; Mosser, Benoît; Girardi, Léo; Montalbán, Josefina
2018-06-01
The red-giant branch bump provides valuable information for the investigation of the internal structure of low-mass stars. Because current models are unable to accurately predict the occurrence and efficiency of mixing processes beyond convective boundaries, one can use the luminosity of the bump—a diagnostic of the maximum extension of the convective envelope during the first-dredge up—as a calibrator for such processes. By combining asteroseismic and spectroscopic constraints, we expand the analysis of the bump to masses and metallicities beyond those previously accessible using globular clusters. Our data set comprises nearly 3000 red-giant stars observed by Kepler and with APOGEE spectra. Using statistical mixture models, we are able to detect the bump in the average seismic parameters ν max and < {{Δ }}ν > , and show that its observed position reveals general trends with mass and metallicity in line with expectations from models. Moreover, our analysis indicates that standard stellar models underestimate the depth of efficiently mixed envelopes. The inclusion of significant overshooting from the base of the convective envelope, with an efficiency that increases with decreasing metallicity, allows us to reproduce the observed location of the bump. Interestingly, this trend was also reported in previous studies of globular clusters.
Tiny bubbles challenge giant turbines: Three Gorges puzzle.
Li, Shengcai
2015-10-06
Since the birth of the first prototype of the modern reaction turbine, cavitation as conjectured by Euler in 1754 always presents as a challenge. Following his theory, the evolution of modern reaction (Francis and Kaplan) turbines has been completed by adding the final piece of the element 'draft-tube' that enables turbines to explore water energy at efficiencies of almost 100%. However, during the last two and a half centuries, with increasing unit capacity and specific speed, the problem of cavitation has been manifested and complicated by the draft-tube surges rather than being solved. Particularly, during the last 20 years, the fierce competition in the international market for extremely large turbines with compact design has encouraged the development of giant Francis turbines of 700-1000 MW. The first group (24 units) of such giant turbines of 700 MW each was installed in the Three Gorges project. Immediately after commission, a strange erosion phenomenon appeared on the guide vane of the machines that has puzzled professionals. From a multi-disciplinary analysis, this Three Gorges puzzle could reflect an unknown type of cavitation inception presumably triggered by turbulence production from the boundary-layer streak transitional process. It thus presents a fresh challenge not only to this old turbine industry, but also to the fundamental sciences.
Tiny bubbles challenge giant turbines: Three Gorges puzzle
Li, Shengcai
2015-01-01
Since the birth of the first prototype of the modern reaction turbine, cavitation as conjectured by Euler in 1754 always presents as a challenge. Following his theory, the evolution of modern reaction (Francis and Kaplan) turbines has been completed by adding the final piece of the element ‘draft-tube’ that enables turbines to explore water energy at efficiencies of almost 100%. However, during the last two and a half centuries, with increasing unit capacity and specific speed, the problem of cavitation has been manifested and complicated by the draft-tube surges rather than being solved. Particularly, during the last 20 years, the fierce competition in the international market for extremely large turbines with compact design has encouraged the development of giant Francis turbines of 700–1000 MW. The first group (24 units) of such giant turbines of 700 MW each was installed in the Three Gorges project. Immediately after commission, a strange erosion phenomenon appeared on the guide vane of the machines that has puzzled professionals. From a multi-disciplinary analysis, this Three Gorges puzzle could reflect an unknown type of cavitation inception presumably triggered by turbulence production from the boundary-layer streak transitional process. It thus presents a fresh challenge not only to this old turbine industry, but also to the fundamental sciences. PMID:26442144
VK, Varsha; Hallikeri, Kaveri; Girish, HC; Murgod, Sanjay
2014-01-01
Background: Central and Peripheral giant cell granulomas of jaws are uncommon, benign, reactive disorders that are characterized by the presence of numerous multinucleated giant cells and mononuclear cells within a stroma. The origin of the multinucleated giant cells is controversial; probably originating from fusion of histiocytes, endothelial cells and fibroblasts. Objective: To assess the expression of CD34 and CD68 in central and peripheral giant cell granulomas to understand the origin of these multinucleated giant cells. Materials and Methods: Twenty cases of Central and Peripheral giant cell granulomas were evaluated immunohistochemically for CD34 and CD68 proteins expression. Results: Immunopositivity for CD34 was seen only in cytoplasm of endothelial cells of blood vessels; whereas, consistent cytoplasmic immunopositivity for CD68 was seen in few stromal cells. Statistical significance was seen in mean number of multinucleated giant cells, mean number of nuclei in multinucleated giant cells, CD68 expression and ratio of macrophages to multinucleated giant cells among two lesions. Conclusion: Although the central giant cell granulomas share some clinical and histopathological similarities with peripheral giant cell granulomas, differences in mean number of nuclei in multinucleated giant cells and CD68 immunoreactivity may underlie the distinct clinical behavior. PMID:25948986
JPRS Report, Soviet Union, International Affairs.
1987-06-17
Commodities rarely bought on "plastic credit" so far include food products and consumer durables—homes, cars, TV sets, which can be paid for in...capitalist giants’ diktat vis-ä-vis scat- tered and isolated farm producers in Africa and the consumers of food supplied there from the West. Ruinous...ensuring their food self-sufficiency, so- cialist countries cooperate with them in building major hydrotechnical projects and agro- industrial
Membrane Assembly during the Infection Cycle of the Giant Mimivirus
Mutsafi, Yael; Shimoni, Eyal; Shimon, Amir; Minsky, Abraham
2013-01-01
Although extensively studied, the structure, cellular origin and assembly mechanism of internal membranes during viral infection remain unclear. By combining diverse imaging techniques, including the novel Scanning-Transmission Electron Microscopy tomography, we elucidate the structural stages of membrane biogenesis during the assembly of the giant DNA virus Mimivirus. We show that this elaborate multistage process occurs at a well-defined zone localized at the periphery of large viral factories that are generated in the host cytoplasm. Membrane biogenesis is initiated by fusion of multiple vesicles, ∼70 nm in diameter, that apparently derive from the host ER network and enable continuous supply of lipid components to the membrane-assembly zone. The resulting multivesicular bodies subsequently rupture to form large open single-layered membrane sheets from which viral membranes are generated. Membrane generation is accompanied by the assembly of icosahedral viral capsids in a process involving the hypothetical major capsid protein L425 that acts as a scaffolding protein. The assembly model proposed here reveals how multiple Mimivirus progeny can be continuously and efficiently generated and underscores the similarity between the infection cycles of Mimivirus and Vaccinia virus. Moreover, the membrane biogenesis process indicated by our findings provides new insights into the pathways that might mediate assembly of internal viral membranes in general. PMID:23737745
Majidi, Shahram; Grigoryan, Mikayel; Tekle, Wondwossen G; Watanabe, Masaki; Qureshi, Adnan I
2012-01-01
Introduction Intravascular ultrasonography (IVUS) has been shown as a valuable adjunct imaging tool during endovascular procedures but its value in detection of any recurrence during follow up after endovascular coil embolization of large and giant intracranial aneurysms is not reported. Methods A 41 years old man who had been treated using stent assisted coil embolization for cavernous segment aneurysm of the left internal carotid artery underwent 60 month angiographic follow up. Concurrently, IVUS catheter was advanced under fluoroscopic guidance inside the cavernous portion of the left internal carotid artery. Then IVUS images were used to visualize the stent, coil loops, and aneurysm neck. Results The angiographic images were limited because of superimposition of the aneurysm on the parent vessel in all projections. IVUS images demonstrated that the stent was patent along its whole length and there was no sign of stent deformity or in-stent thrombosis. Loops of the coil were visualized as hyperechoic signals inside the aneurysm and there was no sign of herniated loops of coil inside the stent. Conclusion In this case report, we observed that adjunct use of IVUS can provide valuable information not ascertained by angiography during follow up assessment of coil embolized aneurysm. PMID:22737259
Ikeda, Hideki; Ohtsu, Kohzoh; Uye, Shin-Ichi
2011-12-01
Production of podocysts is the exclusive form of asexual reproduction by polyps of the giant jellyfish Nemopilema nomurai, which has been recurrently blooming in the East Asian seas in the last decade. Podocycts consist of a dome-shaped chitinous capsule with laminated structure that encapsulates a mass of cyst cells filled with granules containing nutrient reserves such as proteins, carbohydrates, and lipids. Mitochondria, rough endoplasmic reticulum, and Golgi complexes are scarce in the cytoplasm of these cells, and the staining reaction for RNA is weak, indicating very low metabolic activity. Podocysts are capable of dormancy for at least 5 years without significant change of internal structure or nutrient reserves. Integrated information about spontaneous and artificially induced metamorphosis suggests that the following processes occur during excystment: (1) nematocyst formation in the internal cell mass, (2) stratification of the cell mass into endoderm and ectoderm, (3) extrusion of the cell mass through a gradual opening of the capsule, (4) formation of primordial polyp mouth and tentacles, and (5) metamorphosis to a polyp. We morphologically confirmed that N. nomurai podocysts have the capacity for long-term dormancy, an ability that should contribute to the periodic nature of the massive blooms of medusae of this species.
International Space Station (ISS)
2006-09-17
This view of the International Space Station, back dropped against the blackness of space and Earth, was taken shortly after the Space Shuttle Atlantis undocked from the orbital outpost at 7:50 a.m. CDT during the STS-115 mission. The unlinking completed after six days, two hours and two minutes of joint operations of the installation of the P3/P4 truss. The new 17 ton truss included batteries, electronics, a giant rotating joint, and sported a second pair of 240-foot solar wings. The new solar arrays will eventually double the onboard power of the Station when their electrical systems are brought online during the next shuttle flight, STS-116.
International Space Station (ISS)
2006-09-17
This view of the International Space Station, back dropped against the blackness of space, was taken shortly after the Space Shuttle Atlantis undocked from the orbital outpost at 7:50 a.m. CDT during the STS-115 mission. The unlinking completed after six days, two hours and two minutes of joint operations of the installation of the P3/P4 truss. The new 17 ton truss included batteries, electronics, a giant rotating joint, and sported a second pair of 240-foot solar wings. The new solar arrays will eventually double the onboard power of the Station when their electrical systems are brought online during the next shuttle flight, STS-116.
THERMAL PLASMA IN THE GIANT LOBES OF THE RADIO GALAXY CENTAURUS A
DOE Office of Scientific and Technical Information (OSTI.GOV)
O'Sullivan, S. P.; Feain, I. J.; McClure-Griffiths, N. M.
2013-02-20
We present a Faraday rotation measure (RM) study of the diffuse, polarized, radio emission from the giant lobes of the nearest radio galaxy, Centaurus A. After removal of the smooth Galactic foreground RM component, using an ensemble of background source RMs located outside the giant lobes, we are left with a residual RM signal associated with the giant lobes. We find that the most likely origin of this residual RM is from thermal material mixed throughout the relativistic lobe plasma. The alternative possibility of a thin-skin/boundary layer of magnetoionic material swept up by the expansion of the lobes is highlymore » unlikely since it requires, at least, an order of magnitude enhancement of the swept-up gas over the expected intragroup density on these scales. Strong depolarization observed from 2.3 to 0.96 GHz also supports the presence of a significant amount of thermal gas within the lobes; although depolarization solely due to RM fluctuations in a foreground Faraday screen on scales smaller than the beam cannot be ruled out. Considering the internal Faraday rotation scenario, we find a thermal gas number density of {approx}10{sup -4} cm{sup -3}, implying a total gas mass of {approx}10{sup 10} M {sub Sun} within the lobes. The thermal pressure associated with this gas (with temperature kT {approx} 0.5 keV, obtained from recent X-ray results) is approximately equal to the non-thermal pressure, indicating that over the volume of the lobes, there is approximate equipartition between the thermal gas, radio-emitting electrons, and magnetic field (and potentially any relativistic protons present).« less
CHEMICAL ABUNDANCES IN A SAMPLE OF RED GIANTS IN THE OPEN CLUSTER NGC 2420 FROM APOGEE
DOE Office of Scientific and Technical Information (OSTI.GOV)
Souto, Diogo; Cunha, K.; Smith, V.
NGC 2420 is a ∼2 Gyr old well-populated open cluster that lies about 2 kpc beyond the solar circle, in the general direction of the Galactic anti-center. Most previous abundance studies have found this cluster to be mildly metal-poor, but with a large scatter in the obtained metallicities. Detailed chemical abundance distributions are derived for 12 red-giant members of NGC 2420 via a manual abundance analysis of high-resolution ( R = 22,500) near-infrared ( λ 1.5–1.7 μ m) spectra obtained from the Apache Point Observatory Galactic Evolution Experiment (APOGEE) survey. The sample analyzed contains six stars that are identified asmore » members of the first-ascent red giant branch (RGB), as well as six members of the red clump (RC). We find small scatter in the star-to-star abundances in NGC 2420, with a mean cluster abundance of [Fe/H] = −0.16 ± 0.04 for the 12 red giants. The internal abundance dispersion for all elements (C, N, O, Na, Mg, Al, Si, K, Ca, Ti, V, Cr, Mn, Co and Ni) is also very small (∼0.03–0.06 dex), indicating a uniform cluster abundance distribution within the uncertainties. NGC 2420 is one of the clusters used to calibrate the APOGEE Stellar Parameter and Chemical Abundance Pipeline (ASPCAP). The results from this manual analysis compare well with ASPCAP abundances for most of the elements studied, although for Na, Al, and V there are more significant offsets. No evidence of extra-mixing at the RGB luminosity bump is found in the {sup 12}C and {sup 14}N abundances from the pre-luminosity-bump RGB stars in comparison to the post-He core-flash RC stars.« less
Sampling South Pole-Aitken Basin: The Moonrise Approach
NASA Technical Reports Server (NTRS)
Jolliff, B. L.; Shearer, C. K.; Cohen, B. A.
2012-01-01
The South Pole-Aitken basin (SPA) is the largest of the giant impact basins in the inner Solar System, and its location on Earth s Moon makes it the most accessible. Exploration of SPA through direct collection and analysis of representative materials addresses issues as fundamental as the characteristics of the chemical reservoir from which the Moon originated, early differentiation and production of crust and development of global asymmetry, relationships between magmatic activity and internal thermal evolution, and effects of giant impact events on the terrestrial planets. Owing to its great size and superposition relationships with other lunar impact basins, SPA is the oldest and as such anchors the lunar chronology. Moreover, numerous large impact craters and basins are contained within it such that materials (rocks) of the SPA basin contain a record of the early impact chronology, one less likely to have been affected by the large, late nearside basins (e.g., Imbrium). Understanding the early basin chronology is key to deciphering the sequence and effects of early giant impact bombardment of the inner Solar System. That record exists on the Moon, and materials of the SPA basin will allow us to read that record. Knowledge of the early bombardment history will test - and may reshape - a key paradigm relating to early Solar System evolution. Did the planets form with the alignment of today, or was there a major reorientation of the giant planets that led to destabilization of asteroid orbits, and a cataclysmic bombardment of the inner Solar System hundreds of millions of years after accretion of the planets? Implications include understanding environments for early life-supporting habitats on Earth and Mars, and relationships to new observations of extra-solar planetary systems.
Using Online Citizen Science to Assess Giant Kelp Abundances Across the Globe with Satellite Imagery
NASA Astrophysics Data System (ADS)
Byrnes, J.; Cavanaugh, K. C.; Haupt, A. J.; Trouille, L.; Rosenthal, I.; Bell, T. W.; Rassweiler, A.; Pérez-Matus, A.; Assis, J.
2017-12-01
Global scale long-term data sets that document the patterns and variability of human impacts on marine ecosystems are rare. This lack is particularly glaring for underwater species - even moreso for ecologically important ones. Here we demonstrate how online Citizen Science combined with Landsat satellite imagery can help build a picture of change in the dynamics of giant kelp, an important coastal foundation species around the globe, from the 1984 to the present. Giant kelp canopy is visible from Landsat images, but these images defy easy machine classification. To get useful data, images must be processed by hand. While academic researchers have applied this method successfully at sub-regional scales, unlocking the value of the full global dataset has not been possible until given the massive effort required. Here we present Floating Forests (http://floatingforests.org), an international collaboration between kelp forest researchers and the citizen science organization Zooniverse. Floating Forests provides an interface that allows citizen scientists to identify canopy cover of giant kelp on Landsat images, enabling us to scale up the dataset to the globe. We discuss lessons learned from the initial version of the project launched in 2014, a prototype of an image processing pipeline to bring Landsat imagery to citizen science platforms, methods of assessing accuracy of citizen scientists, and preliminary data from our relaunch of the project. Through this project we have developed generalizable tools to facilitate citizen science-based analysis of Landsat and other satellite and aerial imagery. We hope that this create a powerful dataset to unlock our understanding of how global change has altered these critically important species in the sea.
Talks also presented at the Symposium
NASA Astrophysics Data System (ADS)
Eldridge, J. J.; Bray, J. C.; McClelland, L. A. S.; Xiao, L.
2017-11-01
Internal rotation and magnetism are key ingredients that largely affect explosive stellar deaths (Supernovae and Gamma Ray Bursts) and the properties of stellar remnants (White Dwarfs, Neutron Stars and Black Holes). However, the study of these subtle internal stellar properties has been limited to very indirect proxies. In the last couple of years, exciting asteroseismic results have been obtained by the Kepler satellite. Among these results are 1) The direct measure of the degree of radial differential rotation in many evolved low-mass stars and in a few massive stars, and 2) The detection of strong (>105 G) internal magnetic fields in thousands of red giant stars that had convective cores during their main sequence. I will discuss the impact of these important findings for our understanding of massive star evolution.
Internal Wave-Convection-Mean Flow Interactions
NASA Astrophysics Data System (ADS)
Lecoanet, D.; Couston, L. A.; Favier, B.; Le Bars, M.
2017-12-01
We present a series of simulations of Boussinesq fluid with a nonlinear equation of state which in thermal equilibrium is convective in the bottom part of the domain, but stably stratified in the upper part of the domain. The stably stratified region supports internal gravity waves, which are excited by the convection. The convection can significantly affected by the stably stratified region. Furthermore, the waves in the stable region can interact nonlinearly to drive coherent mean flows which exhibit regular oscillations, similar to the QBO in the Earth's atmosphere. We will describe the dependence of the mean flow oscillations on the properties of the convection which generate the internal waves. This provides a novel framework for understanding mean flow oscillations in the Earth's atmosphere, as well as the atmospheres of giant planets.
Asteroseismology of Red-Giant Stars: Mixed Modes, Differential Rotation, and Eccentric Binaries
NASA Astrophysics Data System (ADS)
Beck, Paul G.
2013-12-01
Astronomers are aware of rotation in stars since Galileo Galilei attributed the movement of sunspots to rotation of the Sun in 1613. In contrast to the Sun, whose surface can be resolved by small telescopes or even the (protected) eye, we detect stars as point sources with no spatial information. Numerous techniques have been developed to derive information about stellar rotation. Unfortunately, most observational data allow only for the surface rotational rate to be inferred. The internal rotational profile, which has a great effect on the stellar structure and evolution, remains hidden below the top layers of the star - the essential is hidden to the eyes. Asteroseismology allows us to "sense" indirectly deep below the stellar surface. Oscillations that propagate through the star provide information about the deep stellar interiors while they also distort the stellar surface in characteristic patterns leading to detectable brightness or velocity variations. Also, certain oscillation modes are sensitive to internal rotation and carry information on how the star is spinning deep inside. Thanks to the unprecedented quality of NASA's space telescope Kepler, numerous detailed observations of stars in various evolutionary stages are available. Such high quality data allow that for many stars, rotation can not only be constrained from surface rotation, but also investigated through seismic studies. The work presented in this thesis focuses on the oscillations and internal rotational gradient of evolved single and binary stars. It is shown that the seismic analysis can reach the cores of oscillating red-giant stars and that these cores are rapidly rotating, while nested in a slowly rotating convective envelope.
Graphene-based magnetless converter of terahertz wave polarization
NASA Astrophysics Data System (ADS)
Melnikova, Veronica S.; Polischuk, Olga V.; Popov, Vyacheslav V.
2016-04-01
The polarization conversion of terahertz radiation by the periodic array of graphene nanoribbons located at the surface of a high-refractive-index dielectric substrate (terahertz prism) is studied theoretically. Giant polarization conversion at the plasmon resonance frequencies takes place without applying external DC magnetic field. It is shown that the total polarization conversion can be reached at the total internal reflection of THz wave from the periodic array of graphene nanoribbons even at room temperature.
Offsets in International Weapons Acquisitions: The Turkish Experience
2002-03-01
future civilian needs, a contract was signed with CASA ( Construcciones Aeronauticas SA) of Spain in 1990 for the joint production of 52 CN-235...housed in a large, newly constructed factory, was to assemble and co-produce the F-16 in Turkiye, and to provide support for the program including...project in Turkiye with Bechtel, the giant U.S. engineering and construction firm based in San Francisco. General Dynamics invested about $20 million
Mass entrainment and turbulence-driven acceleration of ultra-high energy cosmic rays in Centaurus A
NASA Astrophysics Data System (ADS)
Wykes, Sarka; Croston, Judith H.; Hardcastle, Martin J.; Eilek, Jean A.; Biermann, Peter L.; Achterberg, Abraham; Bray, Justin D.; Lazarian, Alex; Haverkorn, Marijke; Protheroe, Ray J.; Bromberg, Omer
2013-10-01
Observations of the FR I radio galaxy Centaurus A in radio, X-ray, and gamma-ray bands provide evidence for lepton acceleration up to several TeV and clues about hadron acceleration to tens of EeV. Synthesising the available observational constraints on the physical conditions and particle content in the jets, inner lobes and giant lobes of Centaurus A, we aim to evaluate its feasibility as an ultra-high-energy cosmic-ray source. We apply several methods of determining jet power and affirm the consistency of various power estimates of ~1 × 1043 erg s-1. Employing scaling relations based on previous results for 3C 31, we estimate particle number densities in the jets, encompassing available radio through X-ray observations. Our model is compatible with the jets ingesting ~3 × 1021 g s-1 of matter via external entrainment from hot gas and ~7 × 1022 g s-1 via internal entrainment from jet-contained stars. This leads to an imbalance between the internal lobe pressure available from radiating particles and magnetic field, and our derived external pressure. Based on knowledge of the external environments of other FR I sources, we estimate the thermal pressure in the giant lobes as 1.5 × 10-12 dyn cm-2, from which we deduce a lower limit to the temperature of ~1.6 × 108 K. Using dynamical and buoyancy arguments, we infer ~440-645 Myr and ~560 Myr as the sound-crossing and buoyancy ages of the giant lobes respectively, inconsistent with their spectral ages. We re-investigate the feasibility of particle acceleration via stochastic processes in the lobes, placing new constraints on the energetics and on turbulent input to the lobes. The same "very hot" temperatures that allow self-consistency between the entrainment calculations and the missing pressure also allow stochastic UHECR acceleration models to work.
Tayebi Meybodi, Ali; Lawton, Michael T; Griswold, Dylan; Mokhtari, Pooneh; Payman, Andre; Tabani, Halima; Yousef, Sonia; Benet, Arnau
2017-09-22
OBJECTIVE In various disease processes, including unclippable aneurysms, a bypass to the upper posterior circulation (UPC) including the superior cerebellar artery (SCA) and posterior cerebral artery (PCA) may be needed. Various revascularization options exist, but the role of intracranial (IC) donors has not been scrutinized. The objective of this study was to evaluate the anatomical feasibility of utilizing the anterior temporal artery (ATA) for revascularization of the UPC. METHODS ATA-SCA and ATA-PCA bypasses were performed on 14 cadaver specimens. After performing an orbitozygomatic craniotomy and opening the basal cisterns, the ATA was divided at the M 3 -M 4 junction and mobilized to the crural cistern to complete an end-to-side bypass to the SCA and PCA. The length of the recipient artery between the anastomosis and origin was measured. RESULTS Seventeen ATAs were found. Successful anastomosis was performed in 14 (82%) of the ATAs. The anastomosis point on the PCA was 14.2 mm from its origin on the basilar artery. The SCA anastomosis point was 10.1 mm from its origin. Three ATAs did not reach the UPC region due to a common opercular origin with the middle temporal artery. The ATA-SCA bypass was also applied to the management of an incompletely coiled SCA aneurysm. CONCLUSIONS The ATA is a promising IC donor for UPC revascularization. The ATA is exposed en route to the proximal SCA and PCA through the pterional-orbitozygomatic approach. Also, the end-to-side anastomosis provides an efficient and straightforward bypass without the need to harvest a graft or perform multiple or difficult anastomoses.
Wrapping of intracranial aneurysms: Single-center series and systematic review of the literature.
Perrini, Paolo; Montemurro, Nicola; Caniglia, Michele; Lazzarotti, Guido; Benedetto, Nicola
2015-01-01
Circumferential wrapping of the aneurysm wall with a variety of materials is a well-known therapeutic approach for the repair of unclippable intracranial aneurysms (IAs). Wrapping materials can stimulate foreign-body inflammatory reactions and parent artery narrowing with resultant ischemic stroke. In this study, a single-center retrospective review of the outcome with wrapping of IAs is presented beside an analysis of existing literature. For the institutional analysis, all patients who underwent wrapping of IAs in the last five years were analyzed. For the analysis of the literature, a MEDLINE search between 1990 and the present was performed for clinical series reporting wrapping of IAs. Specifically, the risk of rebleeding, cerebrovascular complications, and the incidence of granuloma formation were evaluated. Two hundred and ninety patients with IA were surgically treated in our department. Fifteen patients (5.2%) underwent wrapping of IA. Early parent artery narrowing occurred in one patient (6.7%) and was associated with ischemic stroke. Delayed cerebrovascular complications, including parent artery narrowing (one case), granuloma formation (one case), and fatal bleeding from an unruptured aneurysm, occurred in three patients (20%). For the review of the literature, 197 cases of wrapped aneurysms were collected. Bleeding after wrapping occurred in 16 (12%) of the patients with ruptured aneurysms. Acute ischemic complications were reported in 7 cases (3.5%) and granuloma formation was observed in 3 patients (1.5%). These data suggest that the microsurgical wrapping of IAs present a risk of ischemic complications and granuloma formation. Additionally, the rebleeding rate of ruptured aneurysms remains high, although still lower than the natural history of untreated ruptured aneurysms.
Einstein Observatory magnitude-limited X-ray survey of late-type giant and supergiant stars
NASA Technical Reports Server (NTRS)
Maggio, A.; Vaiana, G. S.; Haisch, B. M.; Stern, R. A.; Bookbinder, J.
1990-01-01
Results are presented of an extensive X-ray survey of 380 giant and supergiant stars of spectral types from F to M, carried out with the Einstein Observatory. It was found that the observed F giants or subgiants (slightly evolved stars with a mass M less than about 2 solar masses) are X-ray emitters at the same level of main-sequence stars of similar spectral type. The G giants show a range of emissions more than 3 orders of magnitude wide; some single G giants exist with X-ray luminosities comparable to RS CVn systems, while some nearby large G giants have upper limits on the X-ray emission below typical solar values. The K giants have an observed X-ray emission level significantly lower than F and F giants. None of the 29 M giants were detected, except for one spectroscopic binary.
Vortices in Saturn’s Northern Hemisphere (2008–2015) Observed by Cassini ISS
Trammell, Harold Justin; Li, Liming; Jiang, Xun; Pan, Yefeng; Smith, Mark A.; Bering, Edgar A.; Hörst, Sarah M.; Vasavada, Ashwin R.; Ingersoll, Andrew P.; Janssen, Michael A.; West, Robert A.; Porco, Carolyn C.; Li, Cheng; Simon, Amy A.; Baines, Kevin H.
2018-01-01
We use observations from the Imaging Science Subsystem on Cassini to create maps of Saturn’s Northern Hemisphere (NH) from 2008 to 2015, a time period including a seasonal transition (i.e., Spring Equinox in 2009) and the 2010 giant storm. The processed maps are used to investigate vortices in the NH during the period of 2008–2015. All recorded vortices have diameters (east-west) smaller than 6000 km except for the largest vortex that developed from the 2010 giant storm. The largest vortex decreased its diameter from ~11000 km in 2011 to ~5000 km in 2015, and its average diameter is ~6500 km during the period of 2011–2015. The largest vortex lasts at least 4 years, which is much longer than the lifetimes of most vortices (less than 1 year). The largest vortex drifts to north, which can be explained by the beta drift effect. The number of vortices displays varying behaviors in the meridional direction, in which the 2010 giant storm significantly affects the generation and development of vortices in the middle latitudes (25–45°N). In the higher latitudes (45–90°N), the number of vortices also displays strong temporal variations. The solar flux and the internal heat do not directly contribute to the vortex activities, leaving the temporal variations of vortices in the higher latitudes (45–90°N) unexplained. PMID:29629249
Rice, William D.; Liu, Wenyong; Baker, Thomas A.; ...
2015-11-23
Strong quantum confinement in semiconductors can compress the wavefunctions of band electrons and holes to nanometre-scale volumes, significantly enhancing interactions between themselves and individual dopants. In magnetically doped semiconductors, where paramagnetic dopants (such as Mn 2+, Co 2+ and so on) couple to band carriers via strong sp–d spin exchange, giant magneto-optical effects can therefore be realized in confined geometries using few or even single impurity spins. Importantly, however, thermodynamic spin fluctuations become increasingly relevant in this few-spin limit. In nanoscale volumes, the statistical √N fluctuations of N spins are expected to generate giant effective magnetic fields B eff, whichmore » should dramatically impact carrier spin dynamics, even in the absence of any applied field. In this paper, we directly and unambiguously reveal the large B eff that exist in Mn 2+-doped CdSe colloidal nanocrystals using ultrafast optical spectroscopy. At zero applied magnetic field, extremely rapid (300–600 GHz) spin precession of photoinjected electrons is observed, indicating B eff ~ 15-30 T for electrons. Precession frequencies exceed 2 THz in applied magnetic fields. Finally, these signals arise from electron precession about the random fields due to statistically incomplete cancellation of the embedded Mn 2+ moments, thereby revealing the initial coherent dynamics of magnetic polaron formation, and highlighting the importance of magnetization fluctuations on carrier spin dynamics in nanomaterials.« less
Lithium in giant stars in NGC 752 and M67
NASA Astrophysics Data System (ADS)
Pilachowski, Catherine; Saha, A.; Hobbs, L. M.
1988-04-01
Spectra of giant stars in the intermediate-age galactic cluster NGC 752 and in the old cluster M67 have been examined for the presence of Li I λ6707. The lithium feature is not present in any of the M67 giants observed, leading to upper-limit abundances of log ɛ(Li) ≤ -1.0 to 0.3. While lithium is not present in most NGC 752 giants, the feature is strong in two giants, Heinemann 77 and 208, log ɛ(Li) = +1.1 and +1.4, respectively. In the remaining giants in NGC 752, log ɛ(Li) < 0.5. The absence of lithium in M67 giants may be because these giants evolve from progenitors in the region of the main-sequence lithium dip.
78 FR 50346 - Atlantic Highly Migratory Species; Atlantic Bluefin Tuna Fisheries
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-19
... large medium or giant BFT to three large medium or giant BFT for the September, October through November... retention limit of one large medium or giant BFT (measuring 73 inches (185 cm) curved fork length (CFL) or... one large medium or giant BFT as follows: Two large medium or giant BFT for January (76 FR 76900...
Scanning Probe Microscopy on heterogeneous CaCu3Ti4O12 thin films
2011-01-01
The conductive atomic force microscopy provided a local characterization of the dielectric heterogeneities in CaCu3Ti4O12 (CCTO) thin films deposited by MOCVD on IrO2 bottom electrode. In particular, both techniques have been employed to clarify the role of the inter- and sub-granular features in terms of conductive and insulating regions. The microstructure and the dielectric properties of CCTO thin films have been studied and the evidence of internal barriers in CCTO thin films has been provided. The role of internal barriers and the possible explanation for the extrinsic origin of the giant dielectric response in CCTO has been evaluated. PMID:21711646
2000-11-07
In the Space Station Processing Facility, workers applaud the turnover of the P6 Integrated Truss Structure by International Space Station ground operations to the NASA shuttle integration team in a special ceremony. Standing in front are STS-97 Mission Specialists Joe Tanner and Carlos Noriega plus Pilot Mike Broomfield. Behind and left of Tanner is Mission Specialist Marc Garneau. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission involves two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at 10:05 p.m. EST
Scanning Probe Microscopy on heterogeneous CaCu3Ti4O12 thin films
NASA Astrophysics Data System (ADS)
Fiorenza, Patrick; Lo Nigro, Raffaella; Raineri, Vito
2011-12-01
The conductive atomic force microscopy provided a local characterization of the dielectric heterogeneities in CaCu3Ti4O12 (CCTO) thin films deposited by MOCVD on IrO2 bottom electrode. In particular, both techniques have been employed to clarify the role of the inter- and sub-granular features in terms of conductive and insulating regions. The microstructure and the dielectric properties of CCTO thin films have been studied and the evidence of internal barriers in CCTO thin films has been provided. The role of internal barriers and the possible explanation for the extrinsic origin of the giant dielectric response in CCTO has been evaluated.
Scanning Probe Microscopy on heterogeneous CaCu3Ti4O12 thin films.
Fiorenza, Patrick; Lo Nigro, Raffaella; Raineri, Vito
2011-02-04
The conductive atomic force microscopy provided a local characterization of the dielectric heterogeneities in CaCu3Ti4O12 (CCTO) thin films deposited by MOCVD on IrO2 bottom electrode. In particular, both techniques have been employed to clarify the role of the inter- and sub-granular features in terms of conductive and insulating regions. The microstructure and the dielectric properties of CCTO thin films have been studied and the evidence of internal barriers in CCTO thin films has been provided. The role of internal barriers and the possible explanation for the extrinsic origin of the giant dielectric response in CCTO has been evaluated.
Evolution of close binary systems: Observational aspects
NASA Technical Reports Server (NTRS)
Plavec, M. J.
1981-01-01
Detached close binary systems define the main sequence band satisfactorily, but very little is known about the masses of giants and supergiants. High dispersion international ultraviolet explorer satellite observations promise an improvement, since blue companions are now frequently found to late type supergiants. Mu Sagittaril and in particular Xi Aurigae are discussed in more detail. The barium star abundance anomaly appears to be due to mass transfer in interacting systems. The symbiotic stars are another type of binary systems containing late type giants; several possible models for the hotter star and for the type of interaction are discussed. The W Serpentis stars appear to be Algols in the rapid phase of mass transfer, but a possible link relating them to the symbiotics is also indicated. Evidence of hot circumstellar plasmas has now been found in several ordinary Algols; there may exist a smooth transition between very quiescent Algols and the W Serpentis stars. Beta Lyrae is discussed in the light of new spectrophotometric results.
Vargas-Mancilla, Juan; Torrero-Serrato, María A; Palacios-Rodríguez, Aarón J; Rodríguez-de León, Gloria B; Montes-Rodríguez, Metzeri I; Mendoza-Novelo, Birzabith
2018-04-16
The giant omphalocele (GO) represents a challenge for the pediatric surgeon in its management and wall abdominoplasty. Here, we report the outcome of a case in which a GO in a newborn patient was repaired with an implant derived from decellularized bovine pericardium crosslinked with oligourethane. The implantation time was extended for 6 months. This was then followed up by the retrieval of the implant and the subsequent reconstruction in a second surgical time by the closure of the abdominal wall fascia. A short hospital stay, early integration into the patient's family environment, as well as early onset of the oral route without special care of the implant or reconstructed wall nor food restrictions were observed. The reduced presence of the complications described in the literature after application of surgical meshes suggests that this implant can be an effective and safe alternative method in the treatment of abdominal wall defects such as GO. © 2018 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.
MAGNETAR FIELD EVOLUTION AND CRUSTAL PLASTICITY
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lander, S. K., E-mail: skl@soton.ac.uk
2016-06-20
The activity of magnetars is believed to be powered by colossal magnetic energy reservoirs. We sketch an evolutionary picture in which internal field evolution in magnetars generates a twisted corona, from which energy may be released suddenly in a single giant flare, or more gradually through smaller outbursts and persistent emission. Given the ages of magnetars and the energy of their giant flares, we suggest that their evolution is driven by a novel mechanism: magnetic flux transport/decay due to persistent plastic flow in the crust, which would invalidate the common assumption that the crustal lattice is static and evolves onlymore » under Hall drift and Ohmic decay. We estimate the field strength required to induce plastic flow as a function of crustal depth, and the viscosity of the plastic phase. The star’s superconducting core may also play a role in magnetar field evolution, depending on the star’s spindown history and how rotational vortices and magnetic fluxtubes interact.« less
Giant Double Radio Source DA 240: Purveyor of Galaxies
NASA Astrophysics Data System (ADS)
Chen, Ru-Rong; Strom, Richard; Peng, Bo
2018-05-01
Galaxies of stars are building blocks of the baryonic universe. Their composition, structure, and kinematics have been well studied, but details of their origins remain sketchy. The collapse of gas clouds, induced by external forces whereby gravity overcomes internal pressure to form stars, is the likely starting point. Among the perturbing initiators of galaxy formation, radio source beams (jets) are quite effective. Typically, a beam may spawn one galaxy, though instances of several aligned with the radio axis are known. Recently, we found an impressive 14 companions in the lobes of the giant radio galaxy DA 240, which we argue formed as the result of jet instigation. This conclusion is bolstered by the fact that the galaxy groups display Z-shaped symmetry with respect to the radio axis. There is some evidence for star formation among the aligned companions. We also conclude that galaxy alignments at low redshift may derive from line-emitting gas observed in radio components of high-redshift galaxies.
Alton Ochsner's Card File: A Profile of Medical History
Trotter, Michael C.
2010-01-01
Alton Ochsner was a giant of American surgery. His career encompassed patient care, teaching, and research as symbolized on the original seal of the Ochsner Clinic. His ideas were innovative and groundbreaking on many fronts, making him and the Ochsner Clinic nationally and internationally known. Examination of his card file, a simple metal box with 3 × 5 index cards and subject dividers, gives extraordinary insight into the professional interests of this remarkable physician and surgeon. PMID:21603382
The War in Afghanistan: A Legal Analysis
2009-01-01
international law community was saddened to learn that one of its giants, Professor Howard Levie, had passed away at the age of 101. Professor Levie had a long... ages to the present time. Conquerors of old penetrating into the unknown encountered races with strange and unconventional military methods and trod...have been the principal reason why the Security Council began taking a renewed interest in Afghanistan. Let me turn to them briefly. In the late 1990s
NASA Astrophysics Data System (ADS)
Ahmad, Mohamad M.; Yamada, Koji
2014-04-01
In the present work, CaCu3Ti4O12 (CCTO) nanoceramics with different grain sizes were prepared by spark plasma sintering (SPS) at different temperatures (SPS-800, SPS-900, SPS-975, and SPS-1050) of the mechanosynthesized nano-powder. Structural and microstructural properties were studied by XRD and field-emission scanning electron microscope measurements. The grain size of CCTO nanoceramics increases from 80 nm to ˜200 nm for the ceramics sintered at 800 °C and 975 °C, respectively. Further increase of SPS temperature to 1050 °C leads to micro-sized ceramics of 2-3 μm. The electrical and dielectric properties of the investigated ceramics were studied by impedance spectroscopy. Giant dielectric constant was observed in CCTO nanoceramics. The dielectric constant increases with increasing the grain size of the nanoceramics with values of 8.3 × 103, 2.4 × 104, and 3.2 × 104 for SPS-800, SPS-900, and SPS-975, respectively. For the micro-sized SPS-1050 ceramics, the dielectric constant dropped to 2.14 × 104. The dielectric behavior is interpreted within the internal barrier layer capacitance picture due to the electrical inhomogeneity of the ceramics. Besides the resistive grain boundaries that are usually observed in CCTO ceramics, domain boundaries appear as a second source of internal layers in the current nanoceramics.
NASA Astrophysics Data System (ADS)
Soszynski, I.; Udalski, A.; Kubiak, M.; Szymanski, M.; Pietrzynski, G.; Zebrun, K.; Szewczyk, O.; Wyrzykowski, L.
2004-06-01
We present analysis of the large sample of variable red giants from the Large and Small Magellanic Clouds detected during the second phase of the Optical Gravitational Lensing Experiment (OGLE-II) and supplemented with OGLE-III photometry. Comparing pulsation properties of detected objects we find that they constitute two groups with clearly distinct features. In this paper we analyze in detail small amplitude variable red giants (about 15400 and 3000 objects in the LMC and SMC, respectively). The vast majority of these objects are multi-periodic. At least 30% of them exhibit two modes closely spaced in the power spectrum, what likely indicates non-radial oscillations. About 50% exhibit additional so called Long Secondary Period. To distinguish between AGB and RGB red giants we compare PL diagrams of multi-periodic red giants located above and below the tip of the Red Giant Branch (TRGB). The giants above the TRGB form four parallel ridges in the PL diagram. Among much more numerous sample of giants below the TRGB we find objects located on the low luminosity extensions of these ridges, but most of the stars are located on the ridges slightly shifted in log P. We interpret the former as the second ascent AGB red giants and the latter as the first ascent RGB objects. Thus, we empirically show that the pulsating red giants fainter than the TRGB are a mixture of RGB and AGB giants. Finally, we compare the Petersen diagrams of the LMC, SMC and Galactic bulge variable red giants and find that they are basically identical indicating that the variable red giants in all these different stellar environments share similar pulsation properties.
Characterizing Uranus with an Ice giant Planetary Origins Probe (Ice-POP)
NASA Technical Reports Server (NTRS)
Marley, Mark S.; Fortney, Jonathan; Nettelmann, Nadine; Zahnle, Kevin J.
2013-01-01
We now know from studies of planetary transits and microlensing that Neptune-mass planets are ubitquitous and may be the most common class of planets in the Galaxy. As such it is crucial that we understand the formation and evolution of the ice giant planets in our own solar system so that we can better understand planet formation throughout the galaxy. An entry probe mission to Uranus would help accomplish this goal. In fact the Planetary Decadal Survey recommended a Uranus orbiter with entry probe but did not explore in detail the specifications for the entry probe. NASA Ames is currently studying thermal protection system requirements for such a mission and this has led to questions regarding the minimum interesting science payload of such an entry probe. The single most important in-situ measurement for an ice giant entry probe is a measurement of atmospheric composition. For Uranus this would specifically include the methane and noble gas abundances. An in situ measurement of the methane abundance, from below the methane cloud, would constrain the atmospheric carbon abundance, which is believed to be roughly 30 to 50 times solar. There are hints from the transiting planets that extrasolar ice giants show comparable or even greater enhancements of heavy elements compared to their primary stars. However the origin of this carbon enhancement is controversial. Is Uranus a "failed core" of a larger gas giant or was the atmosphere enhanced by accretion of icy planetesimals' Constraining atmospheric abundances of C and perhaps S or even N from below 5 bars would provide badly needed data to address such issues. A measurement of the N abundance would provide clues on the origin of the planetesimals that formed Uranus. Low N-abundance indicates planetesimals from 'warmer' regions where N was mainly in form of NH3, whereas a strong enrichment could indicate planetesimals / cometary material from the colder outer regions of the nebula. Furthermore CO and HCN have been detected in Neptune but not in Uranus. A measurement of the abundance of either would constrain the source mechanisms for these molecules (exogenic or internal). A major surprise from the Galileo Entry Probe was that the heavier noble gases Ar, Kr, and Xe are enhanced in Jupiter's atmosphere at a level comparable to what was seen for the chemically active volatiles N, C, and S. It had been generally expected that Ar, Kr, and Xe would be present in solar abundances, as all were expected to accrete with hydrogen during the gravitational capture of nebular gases. Enhanced abundances of Ar, Kr, and Xe is equivalent to saying that these noble gases have been separated from hydrogen. There are several mechanisms that could accomplish this but these hypotheses require further testing. Measurement of noble gas abundances in an ice giant would constrain the planetary formation and nebular mechanisms responsible for this enhancement. Standard three-layer models of Uranus find that the outer, predominantly H/He layer of Uranus does not reach pressures high enough (approximately 1 Mbar) for H2 to transition to liquid metallic hydrogen. However, valid models can also be constructed with a smaller intermediate water-rich layer, with hydrogen then reaching the metallic hydrogen phase. If this occurs, He should phase separate from the hydrogen and ``rain out," taking along a substantial abundance of Ne, as suggested for Jupiter (and likely also for Saturn). Hence He and Ne depletions could be probes of the planet's structure in the much deeper interior. A determination of Uranus' atmospheric abundances, particularly of the noble gasses, is thus critical to understanding the formation of Uranus, and giant planets in general. These measurements can only be performed with an entry probe. The second key measurement would be a temperature-pressure sounding to provide ground truth for remote measurements of atmospheric temperature and composition and to constrain the internal heat flow. This would also establish that the methane abundance measurements have indeed been made below any possible methane cloud. Finally an ultra stable oscillator would measure wind speeds and constrain atmospheric dynamics. In our presentation we will discuss the importance of all of these measurements and argue that an entry probe is a crucial component of any ice giant mission.
Multifocal tenosynovial giant cell tumors in a child with Noonan syndrome.
Meyers, Arthur B; Awomolo, Agboola O; Szabo, Sara
2017-03-01
Noonan syndrome is a genetic disorder with variable expression of distinctive facial features, webbed neck, chest deformity, short stature, cryptorchidism and congenital heart disease. The association of Noonan syndrome and giant cell granulomas of the mandible is widely reported. However, Noonan syndrome may also be associated with single or multifocal tenosynovial giant cell tumors, also referred to as pigmented villonodular synovitis. We report a child with Noonan syndrome, giant cell granulomas of the mandible and synovial and tenosynovial giant cell tumors involving multiple joints and tendon sheaths who was initially misdiagnosed with juvenile idiopathic arthritis. It is important for radiologists to be aware of the association of Noonan syndrome and multifocal giant cell lesions, which can range from the more commonly described giant cell granulomas of the mandible to isolated or multifocal intra- or extra-articular tenosynovial giant cell tumors or a combination of all of these lesions.
Reyes, Gabriel A.; Halstead, Brian J.; Rose, Jonathan P.; Ersan, Julia S. M.; Jordan, Anna C.; Essert, Allison M.; Fouts, Kristen J.; Fulton, Alexandria M.; Gustafson, K. Benjamin; Wack, Raymond F.; Wylie, Glenn D.; Casazza, Michael L.
2017-11-16
Most extant giant gartersnake (Thamnophis gigas) populations persist in an agro-ecosystem dominated by rice, which serves as a surrogate to the expansive marshes lost to flood control projects and development of the Great Central Valley of California. Knowledge of how giant gartersnakes use the rice agricultural landscape, including how they respond to fallowing, idling, or crop rotations, would greatly benefit conservation of giant gartersnakes by informing more snake-friendly land and water management practices. We studied adult giant gartersnakes at 11 sites in the rice-growing regions of the Sacramento Valley during an extended drought in California to evaluate their response to differences in water availability at the site and individual levels. Although our study indicated that giant gartersnakes make little use of rice fields themselves, and avoid cultivated rice relative to its availability on the landscape, rice is a crucial component of the modern landscape for giant gartersnakes. Giant gartersnakes are strongly associated with the canals that supply water to and drain water from rice fields; these canals provide much more stable habitat than rice fields because they maintain water longer and support marsh-like conditions for most of the giant gartersnake active season. Nonetheless, our results suggest that maintaining canals without neighboring rice fields would be detrimental to giant gartersnake populations, with decreases in giant gartersnake survival rates associated with less rice production in the surrounding landscape. Increased productivity of prey populations, dispersion of potential predators across a larger landscape, and a more secure water supply are just some of the mechanisms by which rice fields might benefit giant gartersnakes in adjacent canals. Results indicate that identifying how rice benefits giant gartersnakes in canals and the extent to which the rice agro-ecosystem could provide these benefits when rice is fallowed would inform the use of water for other purposes without harm to giant gartersnakes. Our study also suggests that without such understanding, maintaining rice and associated canals in the Sacramento Valley is critical for the sustainability of giant gartersnake populations.
NASA Astrophysics Data System (ADS)
Jeffery, David J.; Mazzali, Paolo A.
2007-08-01
Giant steps is a technique to accelerate Monte Carlo radiative transfer in optically-thick cells (which are isotropic and homogeneous in matter properties and into which astrophysical atmospheres are divided) by greatly reducing the number of Monte Carlo steps needed to propagate photon packets through such cells. In an optically-thick cell, packets starting from any point (which can be regarded a point source) well away from the cell wall act essentially as packets diffusing from the point source in an infinite, isotropic, homogeneous atmosphere. One can replace many ordinary Monte Carlo steps that a packet diffusing from the point source takes by a randomly directed giant step whose length is slightly less than the distance to the nearest cell wall point from the point source. The giant step is assigned a time duration equal to the time for the RMS radius for a burst of packets diffusing from the point source to have reached the giant step length. We call assigning giant-step time durations this way RMS-radius (RMSR) synchronization. Propagating packets by series of giant steps in giant-steps random walks in the interiors of optically-thick cells constitutes the technique of giant steps. Giant steps effectively replaces the exact diffusion treatment of ordinary Monte Carlo radiative transfer in optically-thick cells by an approximate diffusion treatment. In this paper, we describe the basic idea of giant steps and report demonstration giant-steps flux calculations for the grey atmosphere. Speed-up factors of order 100 are obtained relative to ordinary Monte Carlo radiative transfer. In practical applications, speed-up factors of order ten and perhaps more are possible. The speed-up factor is likely to be significantly application-dependent and there is a trade-off between speed-up and accuracy. This paper and past work suggest that giant-steps error can probably be kept to a few percent by using sufficiently large boundary-layer optical depths while still maintaining large speed-up factors. Thus, giant steps can be characterized as a moderate accuracy radiative transfer technique. For many applications, the loss of some accuracy may be a tolerable price to pay for the speed-ups gained by using giant steps.
The Lithium Abundances of a Large Sample of Red Giants
NASA Astrophysics Data System (ADS)
Liu, Y. J.; Tan, K. F.; Wang, L.; Zhao, G.; Sato, Bun'ei; Takeda, Y.; Li, H. N.
2014-04-01
The lithium abundances for 378 G/K giants are derived with non-local thermodynamic equilibrium correction considered. Among these are 23 stars that host planetary systems. The lithium abundance is investigated, as a function of metallicity, effective temperature, and rotational velocity, as well as the impact of a giant planet on G/K giants. The results show that the lithium abundance is a function of metallicity and effective temperature. The lithium abundance has no correlation with rotational velocity at v sin i < 10 km s-1. Giants with planets present lower lithium abundance and slow rotational velocity (v sin i < 4 km s-1). Our sample includes three Li-rich G/K giants, 36 Li-normal stars, and 339 Li-depleted stars. The fraction of Li-rich stars in this sample agrees with the general rate of less than 1% in the literature, and the stars that show normal amounts of Li are supposed to possess the same abundance at the current interstellar medium. For the Li-depleted giants, Li-deficiency may have already taken place at the main sequence stage for many intermediate mass (1.5-5 M ⊙) G/K giants. Finally, we present the lithium abundance and kinematic parameters for an enlarged sample of 565 giants using a compilation of the literature, and confirm that the lithium abundance is a function of metallicity and effective temperature. With the enlarged sample, we investigate the differences between the lithium abundance in thin-/thick-disk giants, which indicate that the lithium abundance in thick-disk giants is more depleted than that in thin-disk giants.
CNO isotopes in red giant stars
NASA Technical Reports Server (NTRS)
Wannier, P. G.
1985-01-01
Observational data on CNO abundance ratios in red giants and the interstellar medium (ISM) are analyzed for the implications for the production and distribution of CNO nuclides. The data included isotope abundance measurements for the atmospheres and recent ejecta of cool giants, e.g., carbon stars, S-type stars, red supergiants and oxygen-rich giants beginning an ascent of the giant branch. The contribution of intermediate-mass stars to galactic nuclear evolution is discussed after comparing red giant abundances with ISM abundances, particularly the isotopes O-16, -17 and -18. The O-12/O-18 ratios of red giants are distinctly different from those in interstellar molecular clouds. The CNO values also vary widely from the values found in the solar system.
CNO isotopes in red giant stars
NASA Technical Reports Server (NTRS)
Wannier, P. G.
1985-01-01
The production and distribution of the CNO nuclides is discussed in light of observed abundance ratios in red giants and in the interstellar medium. Isotope abundances have been measured in the atmospheres and in the recent ejecta of cool giants, including carbon stars, S-type stars and red supergiants as well as in oxygen-rich giants making their first ascent of the giant branch. Several of the observations suggest revision of currently accepted nuclear cross-sections and of the mixing processes operating in giant envelopes. By comparing red giant abundances with high-quality observations of the interstellar medium, conclusions are reached about the contribution of intermediate-mass stars to galactic nuclear evolution. The three oxygen isotopes, O-16, -17 and -18, are particularly valuable for such comparison because they reflect three different stages of stellar nucleosynthesis. One remarkable result comes from observations of O-17/O-18 in several classes of red giant stars. The observed range of values for red giants excludes the entire range of values seen in interstellar molecular clouds. Furthermore, both the observations of stars and interstellar clouds exclude the isotopic ratio found in the solar system.
Vibration analysis and experiment of giant magnetostrictive force sensor
NASA Astrophysics Data System (ADS)
Zhu, Zhiwen; Liu, Fang; Zhu, Xingqiao; Wang, Haibo; Xu, Jia
2017-12-01
In this paper, a kind of giant magnetostrictive force sensor is proposed, ans its magneto-mechanical coupled model is developed. The relationship between output voltage of giant magnetostrictive force sensor and input excitation force is obtained. The phenomena of accuracy aggravation in high frequency and delay of giant magnetostrictive sensor are explained. The experimental results show that the model can describe the actual response of giant magnetostrictive force sensor. The new model of giant magnetostrictive sensor has simple form and is easy to be analyzed in theory, which is helpful to be applied in measuring and control fields.
Kinematics and abundances of K giants in the nuclear bulge of the Galaxy
NASA Astrophysics Data System (ADS)
Rich, R. Michael
1990-10-01
Radial velocities have been determined for 53 K giants in Baade's window, which belong to the nuclear bulge population and have abundances derived from low resolution spectra. Additional radial velocities for an overlapping sample of 71 bulge K giants show the same dependence of velocity dispersion on abundance; in both samples, the lower velocity dispersion of the metal-rich giants is found to be significant at a level above 90 percent. Extant data support the hypothesis that both M giants and IRAS bulge sources follow steep density laws similar to that which has been predicted for the metal-rick K giants. The abundance distribution of 88 K giants in Baade's window is noted to be notably well fitted by the simple, 'closed box' model of chemical evolution.
Understanding Li enhancement in K giants and role of accurate parallaxes
NASA Astrophysics Data System (ADS)
Singh, Raghubar; Reddy, B. E.
2018-04-01
Our recent studies based on a large sample of K giants with Hipparcos parallaxes and spectroscopic analysis resulted more than a dozen new Li-rich K giants including few super Li-rich ones. Most of the Li-rich K giants including the new ones appear to occur at the luminosity bump in the HR diagram. However, one can't rule out the possibility of overlap with the clump region where core He-burning K giants reside post He-flash at the tip of RGB. It is important to distinguish field K giants of clump from the bump region in the HR diagram to understand clues for Li production in K giants. In this poster, we explore whether GAIA parallaxes improve to disentangle clump from bump region, more precisely.
Giant aneurysms: A gender-specific complication of Kawasaki disease?
Dietz, Sanne M; Kuipers, Irene M; Tacke, Carline E A; Koole, Jeffrey C D; Hutten, Barbara A; Kuijpers, Taco W
2017-10-01
Kawasaki disease (KD) is a pediatric vasculitis of unknown origin. Its main complication is the development of coronary artery aneurysms (CAA) with giant CAA at the end of the spectrum. In this cohort study, we evaluated the association between patient characteristics and the development of giant CAA based on z-scores. Multivariable, multinomial logistic regression analysis was used to identify variables associated with giant CAA. A total of 301 KD patients, comprising 216 patients without enlargement, 45 with small-sized, 19 with medium-sized, and 21 with giant CAA with all echocardiographies at our center were retrospectively included. Remarkably, 95% of patients with giant CAA were boys. In addition to 'no/late intravenous immunoglobulin (IVIG) treatment', 'male gender' (OR 16.23, 95% CI 1.88-140.13), 'age<1 year' (OR 7.49, 95% CI 2.29-24.46), and 'IVIG re-treatment (9.79, 95% CI 2.79-34.37)' were significantly associated with an increased risk of giant CAA, with patients without enlargement as reference. Compared to patients with medium-sized CAA, 'IVIG re-treatment' was significantly associated with giant CAA. The majority of giant CAA continued to increase in size during the first 40 days. We identified risk factors associated with an increased risk of giant CAA. The difference in variables between the giant CAA group and the other CAA subgroups suggests a separation between patients with the treatment-resistant giant CAA and the other IVIG-responsive patients, in which gender may be factored as a most relevant genetic trait. The increase in size during the first 2 months indicates the need for repeated echocardiography. Copyright © 2017 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.
Construction and analysis of a giant gartersnake (Thamnophis gigas) population projection model
Rose, Jonathan P.; Ersan, Julia S. M.; Wylie, Glenn D.; Casazza, Michael L.; Halstead, Brian J.
2018-03-19
The giant gartersnake (Thamnophis gigas) is a state and federally threatened species precinctive to California. The range of the giant gartersnake has contracted in the last century because its wetland habitat has been drained for agriculture and development. As a result of this habitat alteration, giant gartersnakes now largely persist in and near rice agriculture in the Sacramento Valley, because the system of canals that conveys water for rice growing approximates historical wetland habitat. Many aspects of the demography of giant gartersnakes are unknown, including how individuals grow throughout their life, how size influences reproduction, and how survival varies over time and among populations. We studied giant gartersnakes throughout the Sacramento Valley of California from 1995 to 2016 using capture-mark-recapture to study the growth, reproduction, and survival of this threatened species. We then use these data to construct an Integral Projection Model, and analyze this demographic model to understand which vital rates contribute most to the growth rate of giant gartersnake populations. We find that giant gartersnakes exhibit indeterminate growth; growth slows as individuals’ age. Fecundity, probability of reproduction, and survival all increase with size, although survival may decline for the largest female giant gartersnakes. The population growth rate of giant gartersnakes is most influenced by the survival and growth of large adult females, and the size at which 1 year old recruits enter the population. Our results indicate that management actions benefitting these influential demographic parameters will have the greatest positive effect on giant gartersnake population growth rates, and therefore population persistence. This study informs the conservation and management of giant gartersnakes and their habitat, and illustrates the effectiveness of hierarchical Bayesian models for the study of rare and elusive species.
The lithium abundances of a large sample of red giants
DOE Office of Scientific and Technical Information (OSTI.GOV)
Liu, Y. J.; Tan, K. F.; Wang, L.
2014-04-20
The lithium abundances for 378 G/K giants are derived with non-local thermodynamic equilibrium correction considered. Among these are 23 stars that host planetary systems. The lithium abundance is investigated, as a function of metallicity, effective temperature, and rotational velocity, as well as the impact of a giant planet on G/K giants. The results show that the lithium abundance is a function of metallicity and effective temperature. The lithium abundance has no correlation with rotational velocity at v sin i < 10 km s{sup –1}. Giants with planets present lower lithium abundance and slow rotational velocity (v sin i < 4more » km s{sup –1}). Our sample includes three Li-rich G/K giants, 36 Li-normal stars, and 339 Li-depleted stars. The fraction of Li-rich stars in this sample agrees with the general rate of less than 1% in the literature, and the stars that show normal amounts of Li are supposed to possess the same abundance at the current interstellar medium. For the Li-depleted giants, Li-deficiency may have already taken place at the main sequence stage for many intermediate mass (1.5-5 M {sub ☉}) G/K giants. Finally, we present the lithium abundance and kinematic parameters for an enlarged sample of 565 giants using a compilation of the literature, and confirm that the lithium abundance is a function of metallicity and effective temperature. With the enlarged sample, we investigate the differences between the lithium abundance in thin-/thick-disk giants, which indicate that the lithium abundance in thick-disk giants is more depleted than that in thin-disk giants.« less
Guo, Wei; Mishra, Sudhanshu; Zhao, Jiangchao; Tang, Jingsi; Zeng, Bo; Kong, Fanli; Ning, Ruihong; Li, Miao; Zhang, Hengzhi; Zeng, Yutian; Tian, Yuanliangzi; Zhong, Yihang; Luo, Hongdi; Liu, Yunhan; Yang, Jiandong; Yang, Mingyao; Zhang, Mingwang; Li, Yan; Ni, Qingyong; Li, Caiwu; Wang, Chengdong; Li, Desheng; Zhang, Hemin; Zuo, Zhili; Li, Ying
2018-01-01
Bamboo-eating giant panda (Ailuropoda melanoleuca) is an enigmatic species, which possesses a carnivore-like short and simple gastrointestinal tract (GIT). Despite the remarkable studies on giant panda, its diet adaptability status continues to be a matter of debate. To resolve this puzzle, we investigated the functional potential of the giant panda gut microbiome using shotgun metagenomic sequencing of fecal samples. We also compared our data with similar data from other animal species representing herbivores, carnivores, and omnivores from current and earlier studies. We found that the giant panda hosts a bear-like gut microbiota distinct from those of herbivores indicated by the metabolic potential of the microbiome in the gut of giant pandas and other mammals. Furthermore, the relative abundance of genes involved in cellulose- and hemicellulose-digestion, and enrichment of enzymes associated with pathways of amino acid degradation and biosynthetic reactions in giant pandas echoed a carnivore-like microbiome. Most significantly, the enzyme assay of the giant panda's feces indicated the lowest cellulase and xylanase activity among major herbivores, shown by an in-vitro experimental assay of enzyme activity for cellulose and hemicellulose-degradation. All of our results consistently indicate that the giant panda is not specialized to digest cellulose and hemicellulose from its bamboo diet, making the giant panda a good mammalian model to study the unusual link between the gut microbiome and diet. The increased food intake of the giant pandas might be a strategy to compensate for the gut microbiome functions, highlighting a strong need of conservation of the native bamboo forest both in high- and low-altitude ranges to meet the great demand of bamboo diet of giant pandas. PMID:29503636
Guo, Wei; Mishra, Sudhanshu; Zhao, Jiangchao; Tang, Jingsi; Zeng, Bo; Kong, Fanli; Ning, Ruihong; Li, Miao; Zhang, Hengzhi; Zeng, Yutian; Tian, Yuanliangzi; Zhong, Yihang; Luo, Hongdi; Liu, Yunhan; Yang, Jiandong; Yang, Mingyao; Zhang, Mingwang; Li, Yan; Ni, Qingyong; Li, Caiwu; Wang, Chengdong; Li, Desheng; Zhang, Hemin; Zuo, Zhili; Li, Ying
2018-01-01
Bamboo-eating giant panda ( Ailuropoda melanoleuca ) is an enigmatic species, which possesses a carnivore-like short and simple gastrointestinal tract (GIT). Despite the remarkable studies on giant panda, its diet adaptability status continues to be a matter of debate. To resolve this puzzle, we investigated the functional potential of the giant panda gut microbiome using shotgun metagenomic sequencing of fecal samples. We also compared our data with similar data from other animal species representing herbivores, carnivores, and omnivores from current and earlier studies. We found that the giant panda hosts a bear-like gut microbiota distinct from those of herbivores indicated by the metabolic potential of the microbiome in the gut of giant pandas and other mammals. Furthermore, the relative abundance of genes involved in cellulose- and hemicellulose-digestion, and enrichment of enzymes associated with pathways of amino acid degradation and biosynthetic reactions in giant pandas echoed a carnivore-like microbiome. Most significantly, the enzyme assay of the giant panda's feces indicated the lowest cellulase and xylanase activity among major herbivores, shown by an in-vitro experimental assay of enzyme activity for cellulose and hemicellulose-degradation. All of our results consistently indicate that the giant panda is not specialized to digest cellulose and hemicellulose from its bamboo diet, making the giant panda a good mammalian model to study the unusual link between the gut microbiome and diet. The increased food intake of the giant pandas might be a strategy to compensate for the gut microbiome functions, highlighting a strong need of conservation of the native bamboo forest both in high- and low-altitude ranges to meet the great demand of bamboo diet of giant pandas.
A Surprising Alliance: Two Giants of the 20th Century
Sade, Robert M.
2017-01-01
Alexis Carrel and Charles Lindbergh were among the most famous international figures in the 20th century, Carrel, the surgeon-scientist who won a Nobel prize as a young surgeon, and Lindbergh, the aviator-engineer who pioneered aviation and promoted commercial flight throughout his life. Surprisingly, these two amazing individuals came together to collaborate on the early development of extracorporeal circulation. Their work was interrupted by the onset of World War II, which destroyed one of them and nearly destroyed the other. PMID:28528032
2000-10-31
After repair of a cracked cleat on the crawler-transporter, Space Shuttle Endeavour finally rests on Launch Pad 39B. To the left is the Rotating Service Structure. Endeavour is scheduled to be launched Nov. 30 at 10:01 p.m. EST on mission STS-97, the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections
2000-11-28
STS-97 Mission Specialist Carlos Noriega gets help with his boots from suit technician Shelly Grick-Agrella during pre-pack and fit check. Mission STS-97 is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST
2000-11-28
During pre-pack and fit check in the Operations and Checkout Building, STS-97 Commander Brent Jett gets help with his gloves from suit technician Bill Todd. Mission STS-97 is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST
2000-11-28
STS-97 Mission Specialist Joseph Tanner gets help with his boots from suit technician Erin Canlon during check pre-pack and fit check. Mission STS-97 is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST
2000-11-28
STS-97 Pilot Michael Bloomfield gets help with his boots from suit technician Steve Clendenin during pre-pack and fit check. Mission STS-97 is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST
NASA Astrophysics Data System (ADS)
2009-09-01
IBM scientist wins magnetism prizes Stuart Parkin, an applied physicist at IBM's Almaden Research Center, has won the European Geophysical Society's Néel Medal and the Magnetism Award from the International Union of Pure and Applied Physics (IUPAP) for his fundamental contributions to nanodevices used in information storage. Parkin's research on giant magnetoresistance in the late 1980s led IBM to develop computer hard drives that packed 1000 times more data onto a disk; his recent work focuses on increasing the storage capacity of solid-state electronic devices.
Chromospheres of two red giants in NGC 6752
NASA Technical Reports Server (NTRS)
Dupree, A. K.; Hartmann, L.; Harper, G. M.; Jordan, Carole; Rodgers, A. W.
1990-01-01
Two red giant stars, A31 and A59, in the globular cluster NGC 6752 exhibit Mg II (2800 A) emission with surface fluxes comparable to those observed among metal-deficient halo field giants, and among low-activity Population I giants. Optical echelle spectra of these cluster giants reveal emission in the core of the Ca II K (3933.7 A) line, and in the wing of the H-alpha (6562.8 A) profile. Asymmetries exist both in the emission profiles and the line cores. These observations demonstrate unequivocally the existence of chromospheres among old halo population giants, and the presence of mass outflow in their atmospheres. Maintenance of a relatively constant level of chromospheric activity on the red giant branch contrasts with the decay of magnetic dynamo activity exhibited by dwarf stars and younger giants. A purely hydrodynamic phenomenon may be responsible for heating the outer atmospheres of these stars, enhancing chromospheric emission, thus extending the atmospheres and facilitating mass loss.
Fatal canine distemper virus infection of giant pandas in China
Feng, Na; Yu, Yicong; Wang, Tiecheng; Wilker, Peter; Wang, Jianzhong; Li, Yuanguo; Sun, Zhe; Gao, Yuwei; Xia, Xianzhu
2016-01-01
We report an outbreak of canine distemper virus (CDV) infection among endangered giant pandas (Ailuropoda melanoleuca). Five of six CDV infected giant pandas died. The surviving giant panda was previously vaccinated against CDV. Genomic sequencing of CDV isolated from one of the infected pandas (giant panda/SX/2014) suggests it belongs to the Asia-1 cluster. The hemagglutinin protein of the isolated virus and virus sequenced from lung samples originating from deceased giant pandas all possessed the substitutions V26M, T213A, K281R, S300N, P340Q, and Y549H. The presence of the Y549H substitution is notable as it is found at the signaling lymphocytic activation molecule (SLAM) receptor-binding site and has been implicated in the emergence of highly pathogenic CDV and host switching. These findings demonstrate that giant pandas are susceptible to CDV and suggest that surveillance and vaccination among all captive giant pandas are warranted to support conservation efforts for this endangered species. PMID:27310722
Fatal canine distemper virus infection of giant pandas in China.
Feng, Na; Yu, Yicong; Wang, Tiecheng; Wilker, Peter; Wang, Jianzhong; Li, Yuanguo; Sun, Zhe; Gao, Yuwei; Xia, Xianzhu
2016-06-16
We report an outbreak of canine distemper virus (CDV) infection among endangered giant pandas (Ailuropoda melanoleuca). Five of six CDV infected giant pandas died. The surviving giant panda was previously vaccinated against CDV. Genomic sequencing of CDV isolated from one of the infected pandas (giant panda/SX/2014) suggests it belongs to the Asia-1 cluster. The hemagglutinin protein of the isolated virus and virus sequenced from lung samples originating from deceased giant pandas all possessed the substitutions V26M, T213A, K281R, S300N, P340Q, and Y549H. The presence of the Y549H substitution is notable as it is found at the signaling lymphocytic activation molecule (SLAM) receptor-binding site and has been implicated in the emergence of highly pathogenic CDV and host switching. These findings demonstrate that giant pandas are susceptible to CDV and suggest that surveillance and vaccination among all captive giant pandas are warranted to support conservation efforts for this endangered species.
Deep learning classification in asteroseismology
NASA Astrophysics Data System (ADS)
Hon, Marc; Stello, Dennis; Yu, Jie
2017-08-01
In the power spectra of oscillating red giants, there are visually distinct features defining stars ascending the red giant branch from those that have commenced helium core burning. We train a 1D convolutional neural network by supervised learning to automatically learn these visual features from images of folded oscillation spectra. By training and testing on Kepler red giants, we achieve an accuracy of up to 99 per cent in separating helium-burning red giants from those ascending the red giant branch. The convolutional neural network additionally shows capability in accurately predicting the evolutionary states of 5379 previously unclassified Kepler red giants, by which we now have greatly increased the number of classified stars.
NASA Technical Reports Server (NTRS)
Drake, Jeremy J.; Lambert, David L.
1994-01-01
Sodium abundances have been determined for eight weak G-band giants whose atmospheres are greatly enriched with products of the CN-cycling H-burning reactions. Systematic errors are minimized by comparing the weak G-band giants to a sample of similar but normal giants. If, further, Ca is selected as a reference element, model atmosphere-related errors should largely be removed. For the weak-G-band stars (Na/Ca) = 0.16 +/- 0.01, which is just possibly greater than the result (Na/Ca) = 0.10 /- 0.03 from the normal giants. This result demonstrates that the atmospheres of the weak G-band giants are not seriously contaminated with products of ON cycling.
Evolutionary dynamics of giant viruses and their virophages.
Wodarz, Dominik
2013-07-01
Giant viruses contain large genomes, encode many proteins atypical for viruses, replicate in large viral factories, and tend to infect protists. The giant virus replication factories can in turn be infected by so called virophages, which are smaller viruses that negatively impact giant virus replication. An example is Mimiviruses that infect the protist Acanthamoeba and that are themselves infected by the virophage Sputnik. This study examines the evolutionary dynamics of this system, using mathematical models. While the models suggest that the virophage population will evolve to increasing degrees of giant virus inhibition, it further suggests that this renders the virophage population prone to extinction due to dynamic instabilities over wide parameter ranges. Implications and conditions required to avoid extinction are discussed. Another interesting result is that virophage presence can fundamentally alter the evolutionary course of the giant virus. While the giant virus is predicted to evolve toward increasing its basic reproductive ratio in the absence of the virophage, the opposite is true in its presence. Therefore, virophages can not only benefit the host population directly by inhibiting the giant viruses but also indirectly by causing giant viruses to evolve toward weaker phenotypes. Experimental tests for this model are suggested.
Evolutionary dynamics of giant viruses and their virophages
Wodarz, Dominik
2013-01-01
Giant viruses contain large genomes, encode many proteins atypical for viruses, replicate in large viral factories, and tend to infect protists. The giant virus replication factories can in turn be infected by so called virophages, which are smaller viruses that negatively impact giant virus replication. An example is Mimiviruses that infect the protist Acanthamoeba and that are themselves infected by the virophage Sputnik. This study examines the evolutionary dynamics of this system, using mathematical models. While the models suggest that the virophage population will evolve to increasing degrees of giant virus inhibition, it further suggests that this renders the virophage population prone to extinction due to dynamic instabilities over wide parameter ranges. Implications and conditions required to avoid extinction are discussed. Another interesting result is that virophage presence can fundamentally alter the evolutionary course of the giant virus. While the giant virus is predicted to evolve toward increasing its basic reproductive ratio in the absence of the virophage, the opposite is true in its presence. Therefore, virophages can not only benefit the host population directly by inhibiting the giant viruses but also indirectly by causing giant viruses to evolve toward weaker phenotypes. Experimental tests for this model are suggested. PMID:23919155
THE PROPERTIES OF HEAVY ELEMENTS IN GIANT PLANET ENVELOPES
DOE Office of Scientific and Technical Information (OSTI.GOV)
Soubiran, François; Militzer, Burkhard
The core-accretion model for giant planet formation suggests a two-layer picture for the initial structure of Jovian planets, with heavy elements in a dense core and a thick H–He envelope. Late planetesimal accretion and core erosion could potentially enrich the H–He envelope in heavy elements, which is supported by the threefold solar metallicity that was measured in Jupiter’s atmosphere by the Galileo entry probe. In order to reproduce the observed gravitational moments of Jupiter and Saturn, models for their interiors include heavy elements, Z , in various proportions. However, their effect on the equation of state of the hydrogen–helium mixturesmore » has not been investigated beyond the ideal mixing approximation. In this article, we report results from ab initio simulations of fully interacting H–He– Z mixtures in order to characterize their equation of state and to analyze possible consequences for the interior structure and evolution of giant planets. Considering C, N, O, Si, Fe, MgO, and SiO{sub 2}, we show that the behavior of heavy elements in H–He mixtures may still be represented by an ideal mixture if the effective volumes and internal energies are chosen appropriately. In the case of oxygen, we also compute the effect on the entropy. We find the resulting changes in the temperature–pressure profile to be small. A homogeneous distribution of 2% oxygen by mass changes the temperature in Jupiter’s interior by only 80 K.« less
The role of macrophages and eosinophils in reactive lesions of the oral cavity.
Aghbali, Amir Ala; Akbarzadeh, Ayshin; Kouhsoltani, Maryam
2018-01-01
Many studies have reported that macrophages and eosinophils are involved in the pathogenesis of several diseases. To the best of our knowledge, this is the first study comparing macrophages and eosinophils in oral reactive lesions. In this study, we aimed to determine the contribution of macrophages and eosinophils to the pathogenesis of oral reactive lesions and the relationships between these biomarkers and the diverse histopathologic features. Seventy-five paraffin-embedded tissue samples were assessed in this study. Five categories (15 cases for each group), including peripheral ossifying fibroma, pyogenic granuloma, fibroma, inflammatory fibrous hyperplasia, and peripheral giant-cell granuloma, were considered. Anti-CD68 immunohistochemical and hematoxylin-eosin staining was carried out. We found that macrophages, but not eosinophils, were a significant internal component of oral reactive lesions. Macrophages were observed in high densities in all studied groups and diffusely distributed or clustered throughout these lesions. The number of macrophages was increased in peripheral giant-cell granuloma compared with other groups. Our findings suggest that macrophages are involved in the pathogenesis and the variation of microscopic features of oral reactive lesions. However, further clinical studies should be conducted to identify the biological process behind macrophages and the molecular interactions of these cells, with the ultimate aim of suggesting a new potential therapeutic target for these lesions. We found that eosinophils were not involved in the fibrotic process and the variation of microscopic features in oral reactive lesions. Our results showed that peripheral giant-cell granulomas highly demonstrated histiocytic characteristics.
Proposed Approach to Stable High Beta Plasmas in ET
NASA Astrophysics Data System (ADS)
Taylor, R. J.; Carter, T. A.; Gauvreau, J.-L.; Gourdain, P.-A.; Grossman, A.; Lafonteese, D. J.; Pace, D. C.; Schmitz, L. W.
2003-10-01
Five second long plasmas have been produced in ET with ease. We need these long pulses to evolve high beta equilibria under controlled conditions. However, equilibrium control is lost to internal disruptions due to the development of giant sawteeth on the 1 second time scale. This time scale is approximately the central energy confinement time, while the central particle confinement time is much longer than 1 second. This persistent limitation is present in ohmic and ICRF heated discharges. MHD stable current profiles have been found using DCON(A.H. Glasser, private communication) but transport related phenomena like giant sawteeth and uncontrolled transport barrier evolution are not yet part of a simple stability study. We are advocating avoiding the evolution of giant sawtooth and conditions responsible for MHD instabilities as opposed to exploring their stabilization. This is equivalent to the statement that self-organized plasmas are in fact not welcome in long pulse tokamaks. We intend to prevent self-organization by the application of a multi-faceted ICRF strategy. The in house technology is ready but the approach needs to be artful and not preconceived. The flexibility built into the ET hardware is likely to help us to find a way to achieve global plasma control. It is essential that this work be pursued geared towards parameter performance and configuration control. Both require a significant commitment to understanding the device physics AND delivering on the engineering required for control and performance.
Armbrust, Laura J; Biller, David S; Bamford, Aubrey; Chun, Ruthanne; Garrett, Laura D; Sanderson, Michael W
2012-05-01
To compare the detection of pulmonary nodules by use of 3-view thoracic radiography and CT in dogs with confirmed neoplasia. Prospective case series. 33 dogs of various breeds. 3 interpreters independently evaluated 3-view thoracic radiography images. The location and size of pulmonary nodules were recorded. Computed tomographic scans of the thorax were obtained and evaluated by a single interpreter. The location, size, margin, internal architecture, and density of pulmonary nodules were recorded. Sensitivity, specificity, positive predictive value, and negative predictive value were calculated for thoracic radiography (with CT as the gold standard). 21 of 33 (64%) dogs had pulmonary nodules or masses detected on CT. Of the dogs that had positive CT findings, 17 of 21 (81%) had pulmonary nodules or masses detected on radiographs by at least 1 interpreter. Sensitivity of radiography ranged from 71% to 95%, and specificity ranged from 67% to 92%. Radiography had a positive predictive value of 83% to 94% and a negative predictive value of 65% to 89%. The 4 dogs that were negative for nodules on thoracic radiography but positive on CT were all large-breed to giant-breed dogs with osteosarcoma. CT was more sensitive than radiography for detection of pulmonary nodules. This was particularly evident in large-breed to giant-breed dogs. Thoracic CT is recommended in large-breed to giant-breed dogs with osteosarcoma if the detection of pulmonary nodules will change treatment.
ORIGIN OF LITHIUM ENRICHMENT IN K GIANTS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kumar, Yerra Bharat; Reddy, Bacham E.; Lambert, David L.
In this Letter, we report on a low-resolution spectroscopic survey for Li-rich K giants among 2000 low-mass (M {<=} 3 M{sub sun}) giants spanning the luminosity range from below to above the luminosity of the clump. Fifteen new Li-rich giants including four super Li-rich K giants (log {epsilon}(Li) {>=}3.2) were discovered. A significant finding is that there is a concentration of Li-rich K giants at the luminosity of the clump or red horizontal branch. This new finding is partly a consequence of the fact that our low-resolution survey is the first large survey to include giants well below and abovemore » the red giant branch (RGB) bump and clump locations in the H-R diagram. Origin of the lithium enrichment may be plausibly attributed to the conversion of {sup 3}He via {sup 7}Be to {sup 7}Li by the Cameron-Fowler mechanism but the location for the onset of the conversion is uncertain. Two possible opportunities to effect this conversion are discussed: the bump in the first ascent of the RGB and the He-core flash at the tip of the RGB. The finite luminosity spread of the Li-rich giants serves to reject the idea that Li enhancement is, in general, a consequence of a giant swallowing a large planet.« less
Revealing the microstructure of the giant component in random graph ensembles
NASA Astrophysics Data System (ADS)
Tishby, Ido; Biham, Ofer; Katzav, Eytan; Kühn, Reimer
2018-04-01
The microstructure of the giant component of the Erdős-Rényi network and other configuration model networks is analyzed using generating function methods. While configuration model networks are uncorrelated, the giant component exhibits a degree distribution which is different from the overall degree distribution of the network and includes degree-degree correlations of all orders. We present exact analytical results for the degree distributions as well as higher-order degree-degree correlations on the giant components of configuration model networks. We show that the degree-degree correlations are essential for the integrity of the giant component, in the sense that the degree distribution alone cannot guarantee that it will consist of a single connected component. To demonstrate the importance and broad applicability of these results, we apply them to the study of the distribution of shortest path lengths on the giant component, percolation on the giant component, and spectra of sparse matrices defined on the giant component. We show that by using the degree distribution on the giant component one obtains high quality results for these properties, which can be further improved by taking the degree-degree correlations into account. This suggests that many existing methods, currently used for the analysis of the whole network, can be adapted in a straightforward fashion to yield results conditioned on the giant component.
KIC 9821622: An interesting lithium-rich giant in the Kepler field
NASA Astrophysics Data System (ADS)
Jofré, E.; Petrucci, R.; García, L.; Gómez, M.
2015-12-01
We report the discovery of a new exceptional young lithium-rich giant, KIC 9821622, in the Kepler field that exhibits an unusually large enhancement of α, Fe-peak, and r-process elements. From high-resolution spectra obtained with GRACES at Gemini North, we derived fundamental parameters and detailed chemical abundances of 23 elements from equivalent widths and synthesis analysis. By combining atmospheric stellar parameters with available asteroseismic data, we obtained the stellar mass, radius, and age. The data analysis reveals that KIC 9821622 is a Li-rich (A(Li)NLTE = 1.80 ± 0.2) intermediate-mass giant star (M = 1.64 M⊙) located at the red giant branch near the luminosity bump. We find unexpectedly elevated abundances of Fe-peak and r-process elements. In addition, as previously reported, we find that this is a young star (2.37 Gyr) with unusually high abundances of α-elements ([α/Fe] = 0.31). The evolutionary status of KIC 9821622 suggests that its Li-rich nature is the result of internal fresh Li that is synthesized through the Cameron-Fowler mechanism near the luminosity bump. However, its peculiar enhancement of α, Fe-peak, and r-process elements opens the possibility of external contamination by material enriched by a supernova explosion. Although it is less likely, planet accretion cannot be ruled out. Based on observations obtained at the Gemini Observatory, which is operated by the Association of Universities for Research in Astronomy, Inc., under a cooperative agreement with the NSF on behalf of the Gemini partnership: the National Science Foundation (United States), the National Research Council (Canada), CONICYT (Chile), the Australian Research Council (Australia), Ministério da Ciência, Tecnologia e Inovação (Brazil) and Ministerio de Ciencia, Tecnología e Innovación Productiva (Argentina).Appendix A is available in electronic form at http://www.aanda.org
Literature review of giant gartersnake (Thamnophis gigas) biology and conservation
Halstead, Brian J.; Wylie, Glenn D.; Casazza, Michael L.
2015-08-03
This report reviews the available literature on giant gartersnakes (Thamnophis gigas) to compile existing information on this species and identify knowledge gaps that, if addressed, would help to inform conservation efforts for giant gartersnakes. Giant gartersnakes comprise a species of semi-aquatic snake precinctive to wetlands in the Central Valley of California. The diversion of surface water and conversion of wetlands to agricultural and other land uses resulted in the loss of more than 90 percent of natural giant gartersnake habitats. Because of this habitat loss, giant gartersnakes are now listed by the United States and California Endangered Species Acts as Threatened. Most extant populations occur in the rice-growing regions of the Sacramento Valley, which comprises the northern portion of the giant gartersnake’s former range. The huge demand for water in California for agriculture, industry, recreation, and other human consumption, combined with periodic severe drought, places remaining giant gartersnake habitats at increased risk of degradation and loss. This literature review summarizes the available information on giant gartersnake distribution, habitat relations, behavior, demography, and other aspects of its biology relevant to conservation. This information is then compiled into a graphical conceptual model that indicates the importance of different aspects of giant gartersnake biology for maintaining positive population growth, and identifies those areas for which important information relevant for conservation is lacking. Directing research efforts toward these aspects of giant gartersnake ecology will likely result in improvements to conserving this unique species while meeting the high demands for water in California.
The Molecular Structure of Te146 and Its Derivatives in Drosophila Melanogaster
Lovering, R.; Harden, N.; Ashburner, M.
1991-01-01
TE146 is a giant transposon of Drosophila melanogaster. It carries two copies of the white and roughest genes, normally found on the X chromosome. The structure of this transposon has been studied at the molecular level. TE146 may transpose to new chromosome positions, excise and be lost from the genome or undergo internal rearrangements. The termini of TE146 are foldback DNA elements (FB); the transposon also carries two internal FB elements. Loss or internal rearrangement of TE146 involves recombination between different FB elements. These events have been mapped molecularly, by taking advantage of the fact that the FB sequences are composed largely of a regular 155-bp repeat sequence that is cut by the restriction enzyme TaqI, and are shown to be nonrandom. We suggest that these FB-FB exchange events occur by mitotic sister-chromatid exchange in the premeiotic germ line. PMID:1649070
International Lunar Decade Status
NASA Astrophysics Data System (ADS)
Beldavs, VZ; Crisafulli, J.; Dunlop, D.; Foing, B.
2017-09-01
The International Lunar Decade is a global decadal event designed to provide a framework for strategically directed international cooperation for permanent return to the Moon. To be launched July 20, 2019, the 50th anniversary of the giant leap for mankind marked by Neil Armstrong's first step on the Moon, the ILD launch will include events around the world to celebrate space exploration, science, and the expansion of humanity into the Solar System. The ILD framework links lunar exploration and space sciences with the development of enabling technologies, infrastructure, means of financing, laws and policies aimed at lowering the costs and risks of venturing into space. Dramatically reduced costs will broaden the range of opportunities available in space and widen access to space for more states, companies and people worldwide. The ILD is intended to bring about the efflorescence of commercial business based on space resources from the Moon, asteroids, comets and other bodies in the Solar System.
Effect of specific antibodies on the excitability of internally perfused squid axons.
Huneeus, F C; Fernandez, H L
1967-11-01
Giant axons from the squid Dosidicus gigas were internally perfused with rabbit antiaxoplasm antibodies and their effect upon the action potential and the membrane potential was studied. Necessary requirements for the antibodies to affect these parameters in a consistent manner were: (a) removal of the bulk of axoplasm from the perfused zone, accomplished by initially perfusing with a cysteine-rich (400 mM) solution, and (b) addition of small amounts of cysteine (30 mM) to the antibody-containing solution. When these experimental conditions were met, conduction block ensued generally within 3 hr of the first contact of the axon inner surface with the antibody Antineurofilament antibodies and nonspecific antibodies had no effect. External application of antiaxoplasm antibodies had no effect.
NASA Astrophysics Data System (ADS)
Beldavs, Vid; Atvars, Aigars; Ubelis, Arnolds; Salmins, Kalvis; Crisafulli, Jim; Dunlop, David; Foing, Bernard
2015-04-01
In 1957 at the dawn of the space age the United Nations launched the International Geophysical Year which had a profound impact on collaboration among scientists around the globe. Its legacy includes several major scientific organizations as well as the beginnings of collaboration among nations that see themselves as competitors on Earth. The Soviet Union and the United States made many attempts at collaboration in space while building weapons systems to destroy each other. Space technologies have become the infrastructure for the ubiquitous smart phone with global telecommunications, navigation, weather forecasting, environmental monitoring, and hundreds of other applications. In 2015, the International Year of Light, several conferences will be held exploring the idea of an International Lunar Decade1 An informal group, the International Lunar Decade Working Group (ILDWG) has been formed to plan the launch of the International Lunar Decade in 2017, the 60th Anniversary of the International Geophysical Year. This report will cover the progress of the ILDWG covering conferences planned, international organizations involved and key publications. The activities of the ILDWG can be followed at http://2014giantleap.aerospacehawaii.info/. References [1] V. Beldavs, 2014 'The International Lunar Decade', The Space Review, http://www.thespacereview.com/article/2431/1
Modeling and simulation of flow field in giant magnetostrictive pump
NASA Astrophysics Data System (ADS)
Zhao, Yapeng; Ren, Shiyong; Lu, Quanguo
2017-09-01
Recent years, there has been significant research in the design and analysis of giant magnetostrictive pump. In this paper, the flow field model of giant magnetostrictive pump was established and the relationship between pressure loss and working frequency of piston was studied by numerical simulation method. Then, the influence of different pump chamber height on pressure loss in giant magnetostrictive pump was studied by means of flow field simulation. Finally, the fluid pressure and velocity vector distribution in giant magnetostrictive pump chamber were simulated.
Burkhardt, Jan-Karl; Yousef, Sonia; Tabani, Halima; Benet, Arnau; Rubio, Roberto Rodriguez; Lawton, Michael T
2018-05-12
Distal middle cerebral artery (MCA) aneurysms often have non-saccular morphology and cannot be clipped, requiring revascularization and trapping instead. Combination bypasses are needed when 2 arteries exit the aneurysm, and extracranial-intracranial and intracranial-intracranial bypasses can be used. This video demonstrates a combination bypass used to treat a previously stented distal MCA aneurysm with both a superficial temporal artery (STA)-to-MCA bypass and an M2-to-M2 reanastomosis. This 56-yr-old man presented with distal left-sided MCA aneurysm 2 years earlier and attempted stent-assisted coiling was aborted after the aneurysm was perforated with stenting alone. Follow-up angiography demonstrated progressive aneurysm enlargement, and he was referred for surgery. The patient consented for the procedure and a pterional craniotomy extended posteriorly exposed the distal Sylvian fissure and efferent M4-cortical arteries. After splitting the Sylvian fissure, the "flash fluorescence" technique with indocyanine green (ICG) videoangiography identified an M4 recipient artery from the deeper of 2 exiting branches for STA-MCA bypass.1 The aneurysm was then trapped, and inflow and the more superficial outflow arteries were anastomosed end to end (M2-M2 in-situ bypass). A platelet plug that developed at the reanastomosis site was broken apart with mechanical manipulation, and ICG videoangiography demonstrated patency of both bypasses. The patient recovered without any neurological deficits, and postoperative computed tomography angiography confirmed bypass patency. Combination bypasses are needed when unclippable bifurcation aneurysms require revascularization. Careful intraoperative evaluation of patency of the bypass is imperative and helps identifying and addressing any potential early bypass occlusion.
Fukuda, Hitoshi; Iwasaki, Koichi; Murao, Kenichi; Yamagata, Sen; Lo, Benjamin W.Y.; Macdonald, R. Loch
2014-01-01
Background: While clipping cerebral aneurysms at the neck is optimal, in some cases this is not possible and other strategies are necessary. The purpose of this study was to describe the incidence, risk factors, and outcomes for inability to clip reconstruct ruptured anterior communicating artery (ACoA) aneurysms. Methods: Of the 70 cases of ruptured ACoA aneurysms between January 2006 and December 2013, our institutional experience revealed four cases of small ACoA aneurysms that had been considered clippable prior to operation but required trapping. When a unilateral A2 segment of anterior cerebral artery (ACA) was compromised by trapping, revascularization was performed by bypass surgery. Clinical presentation, angiographic characteristics, operative approach, intraoperative findings, and treatment outcomes were assessed. Results: Very small aneurysm under 3 mm was a risk factor for unexpected trapping. The reason for unexpected trapping was laceration of the aneurysmal neck in two cases, and lack of clippaple component due to disintegration of entire aneurysmal wall at the time of rupture in the others. Aneurysms with bilateral A1 were treated with sole trapping through pterional approach in two cases. The other two cases had hypoplastic unilateral A1 segment of ACA and were treated with combination of aneurysm trapping and revascularization of A2 segment of ACA through interhemispheric approach. No patients had new cerebral infarctions of cortical ACA territory from surgery. Cognitive dysfunction was observed in three cases, but all patients became independent at 12-month follow up. Conclusions: Unexpected trapping was performed when ruptured ACoA aneurysms were unclippable. Trapping with or without bypass can result in reasonable outcomes, with acceptable risk of cognitive dysfunction. PMID:25101201
Giant Planets: Good Neighbors for Habitable Worlds?
NASA Astrophysics Data System (ADS)
Georgakarakos, Nikolaos; Eggl, Siegfried; Dobbs-Dixon, Ian
2018-04-01
The presence of giant planets influences potentially habitable worlds in numerous ways. Massive celestial neighbors can facilitate the formation of planetary cores and modify the influx of asteroids and comets toward Earth analogs later on. Furthermore, giant planets can indirectly change the climate of terrestrial worlds by gravitationally altering their orbits. Investigating 147 well-characterized exoplanetary systems known to date that host a main-sequence star and a giant planet, we show that the presence of “giant neighbors” can reduce a terrestrial planet’s chances to remain habitable, even if both planets have stable orbits. In a small fraction of systems, however, giant planets slightly increase the extent of habitable zones provided that the terrestrial world has a high climate inertia. In providing constraints on where giant planets cease to affect the habitable zone size in a detrimental fashion, we identify prime targets in the search for habitable worlds.
Hadi, Usamah; Rameh, Charbel
2007-01-01
A giant midesophageal diverticulum is a medical rarity that is usually asymptomatic, and discovered incidentally. We report a case of a giant midesophageal diverticulum that revealed itself secondary to food impaction. A literature review on epidemiology, etiology, clinical presentation, investigations, and management of giant midesophageal diverticula will be highlighted.
USDA-ARS?s Scientific Manuscript database
The U.S. Department of Energy has initiated efforts to decrease the nation’s dependence on imported oil by developing domestic renewable sources of cellulosic-derived bioenergy. In this study, giant miscanthus (Miscanthus x giganteus), sugarcane (complex hybrid of Saccharum spp.), and giant reed (Ar...
The minimum area requirements (MAR) for giant panda: an empirical study
Qing, Jing; Yang, Zhisong; He, Ke; Zhang, Zejun; Gu, Xiaodong; Yang, Xuyu; Zhang, Wen; Yang, Biao; Qi, Dunwu; Dai, Qiang
2016-01-01
Habitat fragmentation can reduce population viability, especially for area-sensitive species. The Minimum Area Requirements (MAR) of a population is the area required for the population’s long-term persistence. In this study, the response of occupancy probability of giant pandas against habitat patch size was studied in five of the six mountain ranges inhabited by giant panda, which cover over 78% of the global distribution of giant panda habitat. The probability of giant panda occurrence was positively associated with habitat patch area, and the observed increase in occupancy probability with patch size was higher than that due to passive sampling alone. These results suggest that the giant panda is an area-sensitive species. The MAR for giant panda was estimated to be 114.7 km2 based on analysis of its occupancy probability. Giant panda habitats appear more fragmented in the three southern mountain ranges, while they are large and more continuous in the other two. Establishing corridors among habitat patches can mitigate habitat fragmentation, but expanding habitat patch sizes is necessary in mountain ranges where fragmentation is most intensive. PMID:27929520
The minimum area requirements (MAR) for giant panda: an empirical study.
Qing, Jing; Yang, Zhisong; He, Ke; Zhang, Zejun; Gu, Xiaodong; Yang, Xuyu; Zhang, Wen; Yang, Biao; Qi, Dunwu; Dai, Qiang
2016-12-08
Habitat fragmentation can reduce population viability, especially for area-sensitive species. The Minimum Area Requirements (MAR) of a population is the area required for the population's long-term persistence. In this study, the response of occupancy probability of giant pandas against habitat patch size was studied in five of the six mountain ranges inhabited by giant panda, which cover over 78% of the global distribution of giant panda habitat. The probability of giant panda occurrence was positively associated with habitat patch area, and the observed increase in occupancy probability with patch size was higher than that due to passive sampling alone. These results suggest that the giant panda is an area-sensitive species. The MAR for giant panda was estimated to be 114.7 km 2 based on analysis of its occupancy probability. Giant panda habitats appear more fragmented in the three southern mountain ranges, while they are large and more continuous in the other two. Establishing corridors among habitat patches can mitigate habitat fragmentation, but expanding habitat patch sizes is necessary in mountain ranges where fragmentation is most intensive.
Role of nature reserves in giant panda protection.
Kang, Dongwei; Li, Junqing
2018-02-01
Giant panda (Ailuropoda melanoleuca) is a flagship species in nature conservation of the world; to protect this species, 67 nature reserves have been established in China. To evaluate the protection effect of giant panda nature reserves, we analyzed the variation of giant panda number and habitat area of 23 giant panda nature reserves of Sichuan province based on the national survey data released by State Forestry Administration and Sichuan Forestry Department. Results showed that from the third national survey to the fourth, giant panda number and habitat area of 23 giant panda nature reserves of Sichuan province failed to realize the significant increase. Furthermore, we found that the total population growth rate of 23 nature reserves in the last 12 years was lower than those of the province total of Sichuan and the national total of China, and the total habitat area of the 23 nature reserves was decreasing in the last 12 years, but the province total and national total were all increasing. We propose that giant panda protection should pay more attention to how to improve the protective effects of nature reserves.
Che, T D; Wang, C D; Jin, L; Wei, M; Wu, K; Zhang, Y H; Zhang, H M; Li, D S
2015-03-27
Giant panda cubs have a low survival rate during the newborn and early growth stages. However, the growth and developmental parameters of giant panda cubs during the early lactation stage (from birth to 6 months) are not well known. We examined the growth and development of giant panda cubs by the Chapman growth curve model and estimated the heritability of the maximum growth rate at the early lactation stage. We found that 83 giant panda cubs reached their maximum growth rate at approximately 75-120 days after birth. The body weight of cubs at 75 days was 4285.99 g. Furthermore, we estimated that the heritability of the maximum growth rate was moderate (h(2) = 0.38). Our study describes the growth and development of giant panda cubs at the early lactation stage and provides valuable growth benchmarks. We anticipate that our results will be a starting point for more detailed research on increasing the survival rate of giant panda cubs. Feeding programs for giant panda cubs need further improvement.
NASA Astrophysics Data System (ADS)
Faulkner, John
Fred Hoyle's work on the structure and evolution of red giants, particularly his pathbreaking contribution with Martin Schwarzschild (Hoyle and Schwarzschild 1955), is both lauded and critically assessed. In his later lectures and work with students in the early 1960s, Hoyle presented more physical ways of understanding some of the approximations used, and results obtained, in that seminal paper. Although later ideas by other investigators will be touched upon, Hoyle's viewpoint - that low-mass red giants are essentially white dwarfs with a serious mass-storage problem - is still extremely fruitful. Over the years, I have further developed his method of attack. Relatively recently, I have been able to deepen and broaden the approach, finally extending the theory to provide a unifying treatment of the structure of low-mass stars from the main sequence though both the red-giant and horizontal-branch phases of evolution. Many aspects of these stars that had remained puzzling, even mysterious, for decades have now fallen into place, and some questions have been answered that were not even posed before. With low-mass red giants as the simplest example, this recent work emphasizes that stars, in general, may have at least two distinct but very important centres: (I) a geometrical centre, and (II) a separate nuclear centre, residing in a shell outside a zero-luminosity dense core for example. This two-centre perspective leads to an explicit, analytical, asymptotic theory of low-mass red-giant structure. It enables one to appreciate that the problem of understanding why such stars become red giants is one of anticipating a remarkable yet natural structural bifurcation that occurs in them. This bifurcation occurs because of a combination of known and understandable facts just summarized namely that, following central hydrogen exhaustion, a thin nuclear-burning shell does develop outside a more-or-less dense core. In the resulting theory, both ρsh/ρolinec and ρsh·ρolinec prove to be important self-consistently derived quantities. I present some striking, explicit, asymptotic analytical theorems and results involving these quantities. Perhaps the most astonishingly unexpected and gratifying single result is this: for the very value Nature gives us for the relevant temperature exponent (η=15; CNO cycle) for nuclear-energy generation, ρsh and ρolinec behave in a well defined, precisely inverse manner for a given value of core-mass, Mc. This emphasizes that the internal behaviour of such stars is definitely anti-homologous rather than homologous: dense cores physically promote diffuse surrounding envelopes. I also extend the ideas yet further in a way which (I) links the structural and evolutionary behaviour of stars from the main sequence through horizontal-branch phases of evolution, and (II) also has implications for post-main-sequence developments in more massive stars. The end results is that the post-main-sequence developments of all stars - low-mass, intermediate-mass, and high-mass - as they expand to become giants, are finally seen to be examples of one underpinning fact: that dense cores with this surrounding shells naturally follow hydrogen exhaustion. While "this has been know all along" from oft-repeated computer calculations, we now know why analytically. That matters to true theorists. What follows is a requested, much expanded version of my Cambridge talk.
Zhu, Hui; Wang, Wen-Xiu; Wang, Bao-Qin; Zhu, Xiao-Fu; Wu, Xu-Jin; Ma, Qing-Yi; Chen, De-Kun
2012-06-29
The giant panda (Ailuropoda melanoleuca) is an endangered species and indigenous to China. Interferon-gamma (IFN-γ) is the only member of type □ IFN and is vital for the regulation of host adapted immunity and inflammatory response. Little is known aboutthe FN-γ gene and its roles in giant panda.In this study, IFN-γ gene of Qinling giant panda was amplified from total blood RNA by RT-CPR, cloned, sequenced and analysed. The open reading frame (ORF) of Qinling giant panda IFN-γ encodes 152 amino acidsand is highly similar to Sichuan giant panda with an identity of 99.3% in cDNA sequence. The IFN-γ cDNA sequence was ligated to the pET32a vector and transformed into E. coli BL21 competent cells. Expression of recombinant IFN-γ protein of Qinling giant panda in E. coli was confirmed by SDS-PAGE and Western blot analysis. Biological activity assay indicated that the recombinant IFN-γ protein at the concentration of 4-10 µg/ml activated the giant panda peripheral blood lymphocytes,while at 12 µg/mlinhibited. the activation of the lymphocytes.These findings provide insights into the evolution of giant panda IFN-γ and information regarding amino acid residues essential for their biological activity.
[Prevalence and clinicopathological characteristics of giant cell tumors].
Estrada-Villaseñor, E G; Linares-González, L M; Delgado-Cedillo, E A; González-Guzmán, R; Rico-Martínez, G
2015-01-01
The frequency of giant cell tumors reported in the literature is very variable. Considering that our population has its own features, which distinguish it from the Anglo-Saxon and Asian populations, we think that both the frequency and the clinical characteristics of giant cell tumors in our population are different. The major aim of this paper was to determine the frequency and clinicopathological characteristics of giant cell tumors of the bone. A cross-sectional descriptive study was conducted of the cases diagnosed at our service as giant cell tumors of the bone from January to December 2013. The electronic clinical records, radiologic records and histologic slides from each case were reviewed. Giant cell tumors represented 17% of total bone tumors and 28% of benign tumors. Patients included 13 females and 18 males. The most frequent locations of giant cell tumors were: the proximal tibia, 9 cases (29%), and the distal femur, 6 cases (19%). Forty-five percent of giant cell tumors were associated with aneurysmal bone cyst (ABC) (14 cases) and one case (3%) was malignant. The frequency of giant cell tumors in this case series was intermediate, that is, higher than the one reported in Anglo-Saxon countries (usually low), but without reaching the frequency rates reported in Asian countries (high).
Miller, Robert J.; Lafferty, Kevin D.; Lamy, Thomas; Kui, Li; Rassweiler, Andrew; Reed, Daniel C.
2018-01-01
Foundation species define the ecosystems they live in, but ecologists have often characterized dominant plants as foundational without supporting evidence. Giant kelp has long been considered a marine foundation species due to its complex structure and high productivity; however, there is little quantitative evidence to evaluate this. Here, we apply structural equation modelling to a 15-year time series of reef community data to evaluate how giant kelp affects the reef community. Although species richness was positively associated with giant kelp biomass, most direct paths did not involve giant kelp. Instead, the foundational qualities of giant kelp were driven mostly by indirect effects attributed to its dominant physical structure and associated engineering influence on the ecosystem, rather than by its use as food by invertebrates and fishes. Giant kelp structure has indirect effects because it shades out understorey algae that compete with sessile invertebrates. When released from competition, sessile species in turn increase the diversity of mobile predators. Sea urchin grazing effects could have been misinterpreted as kelp effects, because sea urchins can overgraze giant kelp, understorey algae and sessile invertebrates alike. Our results confirm the high diversity and biomass associated with kelp forests, but highlight how species interactions and habitat attributes can be misconstrued as direct consequences of a foundation species like giant kelp.
Huang, He; Yie, Shangmian; Liu, Yuliang; Wang, Chengdong; Cai, Zhigang; Zhang, Wenping; Lan, Jingchao; Huang, Xiangming; Luo, Li; Cai, Kailai; Hou, Rong; Zhang, Zhihe
2016-01-01
The functional adaptive changes in cyanide detoxification in giant panda appear to be response to dietary transition from typical carnivore to herbivorous bear. We tested the absorption of cyanide contained in bamboo/bamboo shoots with a feeding trial in 20 adult giant pandas. We determined total cyanide content in bamboo shoots and giant panda’s feces, levels of urinary thiocyanate and tissue rhodanese activity using color reactions with a spectrophotometer. Rhodanese expression in liver and kidney at transcription and translation levels were measured using real-time RT-PCR and immunohistochemistry, respectively. We compared differences of rhodanese activity and gene expressions among giant panda, rabbit (herbivore) and cat (carnivore), and between newborn and adult giant pandas. Bamboo shoots contained 3.2 mg/kg of cyanide and giant pandas absorbed more than 65% of cyanide. However, approximately 80% of absorbed cyanide was metabolized to less toxic thiocyanate that was discharged in urine. Rhodanese expression and activity in liver and kidney of giant panda were significantly higher than in cat, but lower than in rabbit (all P < 0.05). Levels in adult pandas were higher than that in newborn cub. Phylogenetic analysis of both nucleotide and amino acid sequences of the rhodanese gene supported a closer relationship of giant panda with carnivores than with herbivores. PMID:27703267
Huang, He; Yie, Shangmian; Liu, Yuliang; Wang, Chengdong; Cai, Zhigang; Zhang, Wenping; Lan, Jingchao; Huang, Xiangming; Luo, Li; Cai, Kailai; Hou, Rong; Zhang, Zhihe
2016-10-05
The functional adaptive changes in cyanide detoxification in giant panda appear to be response to dietary transition from typical carnivore to herbivorous bear. We tested the absorption of cyanide contained in bamboo/bamboo shoots with a feeding trial in 20 adult giant pandas. We determined total cyanide content in bamboo shoots and giant panda's feces, levels of urinary thiocyanate and tissue rhodanese activity using color reactions with a spectrophotometer. Rhodanese expression in liver and kidney at transcription and translation levels were measured using real-time RT-PCR and immunohistochemistry, respectively. We compared differences of rhodanese activity and gene expressions among giant panda, rabbit (herbivore) and cat (carnivore), and between newborn and adult giant pandas. Bamboo shoots contained 3.2 mg/kg of cyanide and giant pandas absorbed more than 65% of cyanide. However, approximately 80% of absorbed cyanide was metabolized to less toxic thiocyanate that was discharged in urine. Rhodanese expression and activity in liver and kidney of giant panda were significantly higher than in cat, but lower than in rabbit (all P < 0.05). Levels in adult pandas were higher than that in newborn cub. Phylogenetic analysis of both nucleotide and amino acid sequences of the rhodanese gene supported a closer relationship of giant panda with carnivores than with herbivores.
Changes of foraging patch selection and utilization by a giant panda after bamboo flowering.
Li, Guochun; Song, Huadong; Altigani, Latifa A A; Zheng, Xueli; Bu, Shuhai
2017-07-01
The bamboo flowering leads to the habitat fragmentation and food quality decline of a giant panda. Few empirical research has been conducted about the giant panda's response to the bamboo flowering. Here, we investigated the characteristics of bamboo stands, giant panda's activity, and selection and utilization of bamboo stands by giant panda in Taibaishan National Nature Reserve, China, over a 3-year period (September 2013-May 2016) during the Fargesia qinlingensis flowering period. Our results indicated that the proportion of whole bamboo stands flowering has gradually expanded from 26.7% in 2013 and 33.9% in 2014 to 52.3% in 2015. Although the flowering bamboo has lower crude protein and higher crude fiber than a non-flowering bamboo, the giant panda still fed on flowering bamboo from the evidence of droppings. The giant panda left its feeding sites and moved to the high elevation along river when the proportion of flowering reached 69.2% at elevation of 2350-2450 m in the third year. With the decline of the quality of bamboo stand of Fargesia qinlingensis, the giant panda abandoned its feeding sites when the threshold value of bamboo flowering reached 56.9-69.2%. Flexibility in foraging strategy and spatial behavior can help the giant panda to better adapt to the environment.
Halstead, Brian J.; Skalos, Shannon M.; Casazza, Michael L.; Wylie, Glenn D.
2015-09-30
Giant gartersnakes (Thamnophis gigas) comprise a species of rare, semi-aquatic snake precinctive to the Central Valley of California. Because of the loss of more than 90% of their natural habitat, giant gartersnakes are listed as Threatened by the United States and California endangered species acts. Little is known, however, about the distribution of giant gartersnakes in the Sacramento Valley, which is where most extant populations occur. We conducted detection-nondetection surveys for giant gartersnakes throughout the rice-growing regions of the Sacramento Valley, and used occupancy models to examine evidence for the effects of landscape-scale GIS-derived variables, local habitat and vegetation composition, and prey communities on patterns of giant gartersnake occurrence. Although our results are based on a relatively small sample of sites, we found that distance to historic marsh, relative fish count, and an interaction of distance to historic marsh with proportion of habitat composed of submerged vegetation were important variables for explaining occupancy of giant gartersnakes. In particular, giant gartersnakes were more likely to occur closer to historic marsh and where relatively fewer fish were captured in traps. At locations in or near historic marsh, giant gartersnakes were more likely to occur in areas with less submerged vegetation, but this relationship was reversed (and more uncertain) at sites distant from historic marsh. Additional research with a larger sample of sites would further elucidate the distribution of giant gartersnakes in the Sacramento Valley.
What made discy galaxies giant?
NASA Astrophysics Data System (ADS)
Saburova, A. S.
2018-01-01
I studied giant discy galaxies with optical radii more than 30 kpc. The comparison of these systems with discy galaxies of moderate sizes revealed that they tend to have higher rotation velocities, B-band luminosities, H I masses and dark-to-luminous mass ratios. The giant discs follow the trend log (M_{H I})(R_{25}) found for normal sized galaxies. It indicates the absence of the peculiarities of evolution of star formation in these galaxies. The H I mass-to-luminosity ratio of giant galaxies appears not to differ from that of normal-sized galaxies, giving evidence in favour of similar star formation efficiency. I also found that the bars and rings occur more frequently among giant discs. I performed mass modelling of the subsample of 18 giant galaxies with available rotation curves and surface photometry data and constructed χ2 maps for the parameters of their dark matter haloes. These estimates indicate that giant discs tend to be formed in larger more massive and rarified dark haloes in comparison to moderate-sized galaxies. However, giant galaxies do not deviate significantly from the relations between the optical sizes and dark halo parameters for moderate-sized galaxies. These findings can rule out the catastrophic scenario of the formation of at least most of giant discs, since they follow the same relations as normal discy galaxies. The giant sizes of the discs can be due to the high radial scale of the dark matter haloes in which they were formed.
Peng, Rui; Liu, Yuliang; Cai, Zhigang; Shen, Fujun; Chen, Jiasong; Hou, Rong; Zou, Fangdong
2018-01-01
Giant pandas, an endangered species, are a powerful symbol of species conservation. Giant pandas may suffer from a variety of diseases. Owing to their highly specialized diet of bamboo, giant pandas are thought to have a relatively weak ability to resist diseases. The spleen is the largest organ in the lymphatic system. However, there is little known about giant panda spleen at a molecular level. Thus, clarifying the regulatory mechanisms of spleen could help us further understand the immune system of the giant panda as well as its conservation. The two giant panda spleens were from two male individuals, one newborn and one an adult, in a non-pathological condition. The whole transcriptomes of mRNA, lncRNA, miRNA, and circRNA in the two spleens were sequenced using the Illumina HiSeq platform. EBseq and IDEG6 were used to observe the differentially expressed genes (DEGs) between these two spleens. Gene Ontology and KEGG analyses were used to annotate the function of DEGs. Furthermore, networks between non-coding RNAs and protein-coding genes were constructed to investigate the relationship between non-coding RNAs and immune-associated genes. By comparative analysis of the whole transcriptomes of these two spleens, we found that one of the major roles of lncRNAs could be involved in the regulation of immune responses of giant panda spleens. In addition, our results also revealed that microRNAs and circRNAs may have evolved to regulate a large set of biological processes of giant panda spleens, and circRNAs may function as miRNA sponges. To our knowledge, this is the first report of lncRNAs and circRNAs in giant panda, which could be a useful resource for further giant panda research. Our study reveals the potential functional roles of miRNAs, lncRNAs, and circRNAs in giant panda spleen. © 2018 The Author(s). Published by S. Karger AG, Basel.
Witton, Mark P.; Habib, Michael B.
2010-01-01
The size and flight mechanics of giant pterosaurs have received considerable research interest for the last century but are confused by conflicting interpretations of pterosaur biology and flight capabilities. Avian biomechanical parameters have often been applied to pterosaurs in such research but, due to considerable differences in avian and pterosaur anatomy, have lead to systematic errors interpreting pterosaur flight mechanics. Such assumptions have lead to assertions that giant pterosaurs were extremely lightweight to facilitate flight or, if more realistic masses are assumed, were flightless. Reappraisal of the proportions, scaling and morphology of giant pterosaur fossils suggests that bird and pterosaur wing structure, gross anatomy and launch kinematics are too different to be considered mechanically interchangeable. Conclusions assuming such interchangeability—including those indicating that giant pterosaurs were flightless—are found to be based on inaccurate and poorly supported assumptions of structural scaling and launch kinematics. Pterosaur bone strength and flap-gliding performance demonstrate that giant pterosaur anatomy was capable of generating sufficient lift and thrust for powered flight as well as resisting flight loading stresses. The retention of flight characteristics across giant pterosaur skeletons and their considerable robustness compared to similarly-massed terrestrial animals suggest that giant pterosaurs were not flightless. Moreover, the term ‘giant pterosaur’ includes at least two radically different forms with very distinct palaeoecological signatures and, accordingly, all but the most basic sweeping conclusions about giant pterosaur flight should be treated with caution. Reappraisal of giant pterosaur material also reveals that the size of the largest pterosaurs, previously suggested to have wingspans up to 13 m and masses up to 544 kg, have been overestimated. Scaling of fragmentary giant pterosaur remains have been misled by distorted fossils or used inappropriate scaling techniques, indicating that 10–11 m wingspans and masses of 200–250 kg are the most reliable upper estimates of known pterosaur size. PMID:21085624
Central circuitry in the jellyfish Aglantha. II: The ring giant and carrier systems
Mackie; Meech
1995-01-01
1. The ring giant axon in the outer nerve ring of the jellyfish Aglantha digitale is a multinucleate syncytium 85 % of which is occupied by an electron-dense fluid-filled vacuole apparently in a GibbsDonnan equilibrium with the surrounding band of cytoplasmic cortex. Micropipette recordings show small (-15 to -25 mV) and large (-62 to -66 mV) resting potentials. Low values, obtained with a high proportion of the micropipette penetrations, are assumed to be from the central vacuole; high values from the cytoplasmic cortex. Background electrical activity includes rhythmic oscillations and synaptic potentials representing hair cell input caused by vibration. 2. After the ring giant axon has been cut, propagating action potentials evoked by stimulation are conducted past the cut and re-enter the axon on the far side. The system responsible (the carrier system) through-conducts at a velocity approximately 25 % of that of the ring giant axon and is probably composed of small neurones running in parallel with it. Numerous small neurones are seen by electron microscopy, some making one-way and some two-way synapses with the ring giant. 3. Despite their different conduction velocities, the two systems normally appear to fire in synchrony and at the velocity of the ring giant axon. We suggest that, once initiated, ring giant spikes propagate rapidly around the margin, firing the carrier neurones through serial synapses and giving them, in effect, the same high conduction velocity. Initiation of ring giant spikes can, however, require input from the carrier system. The spikes are frequently seen to be mounted on slow positive potentials representing summed carrier postsynaptic potentials. 4. The carrier system fires one-for-one with the giant axons of the tentacles and may mediate impulse traffic between the latter and the ring giant axon. We suggest that the carrier system may also provide the pathways from the ring giant to the motor giant axons used in escape swimming. 5. The findings show that the ring giant axon functions in close collaboration with the carrier system, increasing the latter's effective conduction velocity, and that interactions with other neuronal sub-systems are probably mediated exclusively by the carrier system.
Infrared colours and inferred masses of metal-poor giant stars in the Keplerfield
NASA Astrophysics Data System (ADS)
Casey, A. R.; Kennedy, G. M.; Hartle, T. R.; Schlaufman, Kevin C.
2018-05-01
Intrinsically luminous giant stars in the Milky Way are the only potential volume-complete tracers of the distant disk, bulge, and halo. The chemical abundances of metal-poor giants also reflect the compositions of the earliest star-forming regions, providing the initial conditions for the chemical evolution of the Galaxy. However, the intrinsic rarity of metal-poor giants combined with the difficulty of efficiently identifying them with broad-band optical photometry has made it difficult to exploit them for studies of the Milky Way. One long-standing problem is that photometric selections for giant and/or metal-poor stars frequently include a large fraction of metal-rich dwarf contaminants. We re-derive a giant star photometric selection using existing public g-band and narrow-band DDO51photometry obtained in the Keplerfield. Our selection is simple and yields a contamination rate of main-sequence stars of ≲1% and a completeness of about 80 % for giant stars with Teff ≲ 5250 K - subject to the selection function of the spectroscopic surveys used to estimate these rates, and the magnitude range considered (11 ≲ g ≲ 15). While the DDO51filter is known to be sensitive to stellar surface gravity, we further show that the mid-infrared colours of DDO51-selected giants are strongly correlated with spectroscopic metallicity. This extends the infrared metal-poor selection developed by Schlaufman & Casey, demonstrating that the principal contaminants in their selection can be efficiently removed by the photometric separation of dwarfs and giants. This implies that any similarly efficient dwarf/giant discriminant (e.g., Gaiaparallaxes) can be used in conjunction with WISEcolours to select samples of giant stars with high completeness and low contamination. We employ our photometric selection to identify three metal-poor giant candidates in the Keplerfield with global asteroseismic parameters and find that masses inferred for these three stars using standard asteroseismic scaling relations are systematically over-estimated by 20-175%. Taken at face value, this small sample size implies that standard asteroseismic scaling relations over-predict stellar masses for metal-poor giant stars.
A New Giant Titanosauria (Dinosauria: Sauropoda) from the Late Cretaceous Bauru Group, Brazil.
Bandeira, Kamila L N; Medeiros Simbras, Felipe; Batista Machado, Elaine; de Almeida Campos, Diogenes; Oliveira, Gustavo R; Kellner, Alexander W A
2016-01-01
Titanosaurian dinosaurs include some of the largest land-living animals that ever existed, and most were discovered in Cretaceous deposits of Argentina. Here we describe the first Brazilian gigantic titanosaur, Austroposeidon magnificus gen. et sp. nov., from the Late Cretaceous Presidente Prudente Formation (Bauru Group, Paraná Basin), São Paulo State, southeast Brazil. The size of this animal is estimated around 25 meters. It consists of a partial vertebral column composed by the last two cervical and the first dorsal vertebrae, all fairly complete and incomplete portions of at least one sacral and seven dorsal elements. The new species displays four autapomorphies: robust and tall centropostzygapophyseal laminae (cpol) in the last cervical vertebrae; last cervical vertebra bearing the posterior centrodiapophyseal lamina (pcdl) bifurcated; first dorsal vertebra with the anterior and posterior centrodiapophyseal laminae (acdl/pcdl) curved ventrolaterally, and the diapophysis reaching the dorsal margin of the centrum; posterior dorsal vertebra bearing forked spinoprezygapophyseal laminae (sprl). The phylogenetic analysis presented here reveals that Austroposeidon magnificus is the sister group of the Lognkosauria. CT scans reveal some new osteological internal features in the cervical vertebrae such as the intercalation of dense growth rings with camellae, reported for the first time in sauropods. The new taxon further shows that giant titanosaurs were also present in Brazil during the Late Cretaceous and provides new information about the evolution and internal osteological structures in the vertebrae of the Titanosauria clade.
NASA Astrophysics Data System (ADS)
D'Orazi, Valentina; Lucatello, Sara; Lugaro, Maria; Gratton, Raffaele G.; Angelou, George; Bragaglia, Angela; Carretta, Eugenio; Alves-Brito, Alan; Ivans, Inese I.; Masseron, Thomas; Mucciarelli, Alessio
2013-01-01
Observed chemical (anti)correlations in proton-capture elements among globular cluster stars are presently recognized as the signature of self-enrichment from now extinct, previous generations of stars. This defines the multiple population scenario. Since fluorine is also affected by proton captures, determining its abundance in globular clusters provides new and complementary clues regarding the nature of these previous generations and supplies strong observational constraints to the chemical enrichment timescales. In this paper, we present our results on near-infrared CRIRES spectroscopic observations of six cool giant stars in NGC 6656 (M22): the main objective is to derive the F content and its internal variation in this peculiar cluster, which exhibits significant changes in both light- and heavy-element abundances. Across our sample, we detected F variations beyond the measurement uncertainties and found that the F abundances are positively correlated with O and anticorrelated with Na, as expected according to the multiple population framework. Furthermore, our observations reveal an increase in the F content between the two different sub-groups, s-process rich and s-process poor, hosted within M22. The comparison with theoretical models suggests that asymptotic giant stars with masses between 4 and 5 M ⊙ are responsible for the observed chemical pattern, confirming evidence from previous works: the difference in age between the two sub-components in M22 must be not larger than a few hundred Myr. Based on observations taken with ESO telescopes under program 087.0319(A).
NASA Astrophysics Data System (ADS)
Aliseda, Alberto; Bourgoin, Mickael; Eswirp Collaboration
2014-11-01
We present preliminary results from a recent grid turbulence experiment conducted at the ONERA wind tunnel in Modane, France. The ESWIRP Collaboration was conceived to probe the smallest scales of a canonical turbulent flow with very high Reynolds numbers. To achieve this, the largest scales of the turbulence need to be extremely big so that, even with the large separation of scales, the smallest scales would be well above the spatial and temporal resolution of the instruments. The ONERA wind tunnel in Modane (8 m -diameter test section) was chosen as a limit of the biggest large scales achievable in a laboratory setting. A giant inflatable grid (M = 0.8 m) was conceived to induce slowly-decaying homogeneous isotropic turbulence in a large region of the test section, with minimal structural risk. An international team or researchers collected hot wire anemometry, ultrasound anemometry, resonant cantilever anemometry, fast pitot tube anemometry, cold wire thermometry and high-speed particle tracking data of this canonical turbulent flow. While analysis of this large database, which will become publicly available over the next 2 years, has only started, the Taylor-scale Reynolds number is estimated to be between 400 and 800, with Kolmogorov scales as large as a few mm . The ESWIRP Collaboration is formed by an international team of scientists to investigate experimentally the smallest scales of turbulence. It was funded by the European Union to take advantage of the largest wind tunnel in Europe for fundamental research.
A New Giant Titanosauria (Dinosauria: Sauropoda) from the Late Cretaceous Bauru Group, Brazil
2016-01-01
Titanosaurian dinosaurs include some of the largest land-living animals that ever existed, and most were discovered in Cretaceous deposits of Argentina. Here we describe the first Brazilian gigantic titanosaur, Austroposeidon magnificus gen. et sp. nov., from the Late Cretaceous Presidente Prudente Formation (Bauru Group, Paraná Basin), São Paulo State, southeast Brazil. The size of this animal is estimated around 25 meters. It consists of a partial vertebral column composed by the last two cervical and the first dorsal vertebrae, all fairly complete and incomplete portions of at least one sacral and seven dorsal elements. The new species displays four autapomorphies: robust and tall centropostzygapophyseal laminae (cpol) in the last cervical vertebrae; last cervical vertebra bearing the posterior centrodiapophyseal lamina (pcdl) bifurcated; first dorsal vertebra with the anterior and posterior centrodiapophyseal laminae (acdl/pcdl) curved ventrolaterally, and the diapophysis reaching the dorsal margin of the centrum; posterior dorsal vertebra bearing forked spinoprezygapophyseal laminae (sprl). The phylogenetic analysis presented here reveals that Austroposeidon magnificus is the sister group of the Lognkosauria. CT scans reveal some new osteological internal features in the cervical vertebrae such as the intercalation of dense growth rings with camellae, reported for the first time in sauropods. The new taxon further shows that giant titanosaurs were also present in Brazil during the Late Cretaceous and provides new information about the evolution and internal osteological structures in the vertebrae of the Titanosauria clade. PMID:27706250
NASA Astrophysics Data System (ADS)
Smiljanic, R.; Romano, D.; Bragaglia, A.; Donati, P.; Magrini, L.; Friel, E.; Jacobson, H.; Randich, S.; Ventura, P.; Lind, K.; Bergemann, M.; Nordlander, T.; Morel, T.; Pancino, E.; Tautvaišienė, G.; Adibekyan, V.; Tosi, M.; Vallenari, A.; Gilmore, G.; Bensby, T.; François, P.; Koposov, S.; Lanzafame, A. C.; Recio-Blanco, A.; Bayo, A.; Carraro, G.; Casey, A. R.; Costado, M. T.; Franciosini, E.; Heiter, U.; Hill, V.; Hourihane, A.; Jofré, P.; Lardo, C.; de Laverny, P.; Lewis, J.; Monaco, L.; Morbidelli, L.; Sacco, G. G.; Sbordone, L.; Sousa, S. G.; Worley, C. C.; Zaggia, S.
2016-05-01
Context. Stellar evolution models predict that internal mixing should cause some sodium overabundance at the surface of red giants more massive than ~1.5-2.0 M⊙. The surface aluminium abundance should not be affected. Nevertheless, observational results disagree about the presence and/or the degree of Na and Al overabundances. In addition, Galactic chemical evolution models adopting different stellar yields lead to very different predictions for the behavior of [Na/Fe] and [Al/Fe] versus [Fe/H]. Overall, the observed trends of these abundances with metallicity are not well reproduced. Aims: We readdress both issues, using new Na and Al abundances determined within the Gaia-ESO Survey. Our aim is to obtain better observational constraints on the behavior of these elements using two samples: I) more than 600 dwarfs of the solar neighborhood and of open clusters and II) low- and intermediate-mass clump giants in six open clusters. Methods: Abundances were determined using high-resolution UVES spectra. The individual Na abundances were corrected for nonlocal thermodynamic equilibrium effects. For the Al abundances, the order of magnitude of the corrections was estimated for a few representative cases. For giants, the abundance trends with stellar mass are compared to stellar evolution models. For dwarfs, the abundance trends with metallicity and age are compared to detailed chemical evolution models. Results: Abundances of Na in stars with mass below ~2.0 M⊙, and of Al in stars below ~3.0 M⊙, seem to be unaffected by internal mixing processes. For more massive stars, the Na overabundance increases with stellar mass. This trend agrees well with predictions of stellar evolutionary models. For Al, our only cluster with giants more massive than 3.0 M⊙, NGC 6705, is Al enriched. However, this might be related to the environment where the cluster was formed. Chemical evolution models that well fit the observed [Na/Fe] vs. [Fe/H] trend in solar neighborhood dwarfs cannot simultaneously explain the run of [Al/Fe] with [Fe/H], and vice versa. The comparison with stellar ages is hampered by severe uncertainties. Indeed, reliable age estimates are available for only a half of the stars of the sample. We conclude that Al is underproduced by the models, except for stellar ages younger than about 7 Gyr. In addition, some significant source of late Na production seems to be missing in the models. Either current Na and Al yields are affected by large uncertainties, and/or some important Galactic source(s) of these elements has as yet not been taken into account. Based on observations made with the ESO/VLT, at Paranal Observatory, under program 188.B-3002 (The Gaia-ESO Public Spectroscopic Survey), and on data obtained from the ESO Archive originally observed under programs 60.A-9143, 076.B-0263 and 082.D-0726.Table 1 is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/589/A115
77 FR 28496 - Atlantic Highly Migratory Species; Atlantic Bluefin Tuna Fisheries
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-15
... daily retention limit would be the default retention limit of one large medium or giant BFT (measuring... default level of one large medium or giant BFT as follows: Two large medium or giant BFT for the January subquota period (75 FR 79309, December 20, 2010); three large medium or giant BFT for June through November...
Habitat use by giant panda in relation to man-made forest in Wanglang Nature Reserve of China.
Kang, Dongwei; Wang, Xiaorong; Yang, Hongwei; Duan, Lijuan; Li, Junqing
2014-12-01
To evaluate the effectiveness of human restoration in species conservation, in this study, we undertook a field survey of giant panda (Ailuropoda melanoleuca) habitat and man-made forest habitat in Wanglang Nature Reserve of China. Our results revealed that giant panda did not use the man-made forest in this area so far, and that there were significant differences between the giant panda habitat and the man-made forest habitat. Compared with giant panda habitat, the man-made forest habitat was characterized by lower shrub coverage, thinner trees and lower bamboo density. To improve the effectiveness of human restoration, the habitat requirement of giant panda should be fully consider in the whole process of habitat restoration.
Forti, Luiz Carlos; Protti de Andrade, Ana Paula; Camargo, Roberto da Silva; Caldato, Nadia; Moreira, Aldenise Alves
2017-01-01
Atta capiguara is a grass-cutting ant species frequently found in Cerrado biome. However, little is known about the giant nest architecture of this ant. In this study, we investigated the architecture of three A. capiguara nests from a fragment of Cerrado in Botucatu, São Paulo, Brazil. Casts were made of the nests by filling them with cement to permit better visualization of internal structures such as chambers and tunnels. After excavation, the depth and dimensions (length, width, and height) of the chambers were measured. The results showed the shape of Atta capiguara nests consisting of mounds of loose soil with unique features resembling a conic section. The fungus chambers were found distant from the mound of loose soil and were spaced apart and distributed laterally at the soil profile. The waste chambers were located beneath the largest mound of loose soil. Both the fungus and waste chambers were separated and distant. Our study contributes to a better understanding of the so far unknown nest architecture of the grass-cutting ant A. capiguara. PMID:28350352
Kou, Qi; Chen, Jun; Li, Xinzheng; He, Lisheng; Wang, Yong
2017-07-01
Several specimens of the giant deep-sea isopod genus Bathynomus were collected by a deep-sea lander at a depth of 898 m near Hainan Island in the northern South China Sea. After careful examination, this material and the specimens collected from the Gulf of Aden, north-western Indian Ocean, previously reported as Bathynomus sp., were identified to be the same as a new species to the genus. Bathynomus jamesi sp. nov. can be distinguished from the congeners by: the distal margin of pleotelson with 11 or 13 short straight spines and central spine not bifid; uropodal endopod and exopod with distolateral corner slightly pronounced; clypeus with lateral margins concave; and antennal flagellum extending when extended posteriorly reaches the pereonite 3. In addition, Bathynomus jamesi sp. nov. is also supported by molecular analyses based on mitochondrial COI and 16S rRNA gene sequences. The distribution range of the new species includes the western Pacific and north-western Indian Ocean. © 2017 International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and John Wiley & Sons Australia, Ltd.
Dynamical evolution of the Oort cloud
NASA Technical Reports Server (NTRS)
Weissman, P. R.
1985-01-01
New studies of the dynamical evolution of cometary orbits in the Oort cloud are made using a revised version of Weissman's (1982) Monte Carlo simulation model, which more accurately mimics the perturbation of comets by the giant planets. It is shown that perturbations by Saturn and Jupiter provide a substantial barrier to the diffusion of cometary perihelia into the inner solar system. Perturbations by Uranus and Neptune are rarely great enough to remove comets from the Oort cloud, but do serve to scatter the comets in the cloud in initial energy. The new model gives a population of 1.8 to 2.1 x 10 to the 12th comets for the present-day Oort cloud, and a mass of 7 to 8 earth masses. Perturbation of the Oort cloud by giant molecular clouds in the galaxy is discussed, as is evidence for a massive 'inner Oort cloud' internal to the observed one. The possibility of an unseen solar companion orbiting in the Oort cloud and causing periodic comet showers is shown to be dynamically plausible but unlikely, based on the observed cratering rate on the earth and moon.
Adelman, William J.; Taylor, Robert E.
1964-01-01
It was observed that a reduction of the sodium chloride concentration in the external solution bathing a squid giant axon by replacement with sucrose resulted in marked decreases in the peak inward and steady-state outward currents through the axon membrane following a step decrease in membrane potential. These effects are quantitatively acounted for by the increase in series resistance resulting from the decreased conductivity of the sea water and the assumption that the sodium current obeys a relation of the form I = k1C1 - k2C2 where C1, C2 are internal and external ion activities and k1, k2 are independent of concentration. It is concluded that the potassium ion current is independent of the sodium concentration. That the inward current is carried by sodium ions has been confirmed. The electrical potential (or barrier height) profile in the membrane which drives sodium ions appears to be independent of sodium ion concentration or current. A specific effect of the sucrose on hyperpolarizing currents was observed and noted but not investigated in detail. PMID:14232131
Jeong, J; Toida, T; Muneta, Y; Kosiishi, I; Imanari, T; Linhardt, R J; Choi, H S; Wu, S J; Kim, Y S
2001-12-01
Acharan sulfate is a glycosaminoglycan (GAG), having the structure -->4)-2-acetamido-2-deoxy-alpha-D-glucopyranose(1-->4)-2-sulfo-alpha-L-idopyranosyluronic acid (1-->, isolated from the body of the giant African snail Achatina fulica. This GAG represents 3-5% of the dry weight of this snail's soft body tissues. Frozen sections and polyester wax sections of the snail's body were stained by Alcian blue-periodic acid-Schiff's reagent (PAS) to localize acharan sulfate. Alcian blue staining indicated that GAG was mainly secreted into the outer surface of the body from internal granules. A highly mucous material was collected and treated and the acharan sulfate was recovered by ethanol and cetyl pyridinium chloride precipitation. Crude acharan sulfate was purified by DEAE-Sephacel ion-exchange chromatography. Depolymerization of intact mucus and purified acharan sulfate fractions by heparin lyase II (heparitinase I) from Flavobacterium heparinum produced an unsaturated disaccharide as a major product, establishing the repeating unit of acharan sulfate. These results demonstrate that mucus in the granule and secreted to the outside of the body is composed entirely of acharan sulfate.
Genome packaging in EL and Lin68, two giant phiKZ-like bacteriophages of P. aeruginosa.
Sokolova, O S; Shaburova, O V; Pechnikova, E V; Shaytan, A K; Krylov, S V; Kiselev, N A; Krylov, V N
2014-11-01
A unique feature of the Pseudomonas aeruginosa giant phage phiKZ is its way of genome packaging onto a spool-like protein structure, the inner body. Until recently, no similar structures have been detected in other phages. We have studied DNA packaging in P. aeruginosa phages EL and Lin68 using cryo-electron microscopy and revealed the presence of inner bodies. The shape and positioning of the inner body and the density of the DNA packaging in EL are different from those found in phiKZ and Lin68. This internal organization explains how the shorter EL genome is packed into a large EL capsid, which has the same external dimensions as the capsids of phiKZ and Lin68. The similarity in the structural organization in EL and other phiKZ-like phages indicates that EL is phylogenetically related to other phiKZ-like phages, and, despite the lack of detectable DNA homology, EL, phiKZ, and Lin68 descend from a common ancestor. Copyright © 2014 Elsevier Inc. All rights reserved.
Squid Giant Axon Contains Neurofilament Protein mRNA but does not Synthesize Neurofilament Proteins.
Gainer, Harold; House, Shirley; Kim, Dong Sun; Chin, Hemin; Pant, Harish C
2017-04-01
When isolated squid giant axons are incubated in radioactive amino acids, abundant newly synthesized proteins are found in the axoplasm. These proteins are translated in the adaxonal Schwann cells and subsequently transferred into the giant axon. The question as to whether any de novo protein synthesis occurs in the giant axon itself is difficult to resolve because the small contribution of the proteins possibly synthesized intra-axonally is not easily distinguished from the large amounts of the proteins being supplied from the Schwann cells. In this paper, we reexamine this issue by studying the synthesis of endogenous neurofilament (NF) proteins in the axon. Our laboratory previously showed that NF mRNA and protein are present in the squid giant axon, but not in the surrounding adaxonal glia. Therefore, if the isolated squid axon could be shown to contain newly synthesized NF protein de novo, it could not arise from the adaxonal glia. The results of experiments in this paper show that abundant 3H-labeled NF protein is synthesized in the squid giant fiber lobe containing the giant axon's neuronal cell bodies, but despite the presence of NF mRNA in the giant axon no labeled NF protein is detected in the giant axon. This lends support to the glia-axon protein transfer hypothesis which posits that the squid giant axon obtains newly synthesized protein by Schwann cell transfer and not through intra-axonal protein synthesis, and further suggests that the NF mRNA in the axon is in a translationally repressed state.
On Lithium-rich Red Giants. I. Engulfment of Substellar Companions
NASA Astrophysics Data System (ADS)
Aguilera-Gómez, Claudia; Chanamé, Julio; Pinsonneault, Marc H.; Carlberg, Joleen K.
2016-10-01
A small fraction of red giants are known to be lithium (Li) rich, in contradiction with expectations from stellar evolutionary theory. A possible explanation for these atypical giants is the engulfment of an Li-rich planet or brown dwarf by the star. In this work, we model the evolution of Li abundance in canonical red giants including the accretion of a substellar mass companion. We consider a wide range of stellar and companion masses, Li abundances, stellar metallicities, and planetary orbital periods. Based on our calculations, companions with masses lower than 15 {M}J dissolve in the convective envelope and can induce Li enrichment in regimes where extra mixing does not operate. Our models indicate that the accretion of a substellar companion can explain abundances up to A(Li) ≈ 2.2, setting an upper limit for Li-rich giants formed by this mechanism. Giants with higher abundances need another mechanism to be explained. For reasonable planetary distributions, we predict the Li abundance distribution of low-mass giants undergoing planet engulfment, finding that between 1% and 3% of them should have {{A}}({Li})≥slant 1.5. We show that depending on the stellar mass range, this traditional definition of Li-rich giants is misleading, as isolated massive stars would be considered anomalous while giants engulfing a companion would be set aside, flagged as normal. We explore the detectability of companion engulfment, finding that planets with masses higher than ∼ 7 {M}J produce a distinct signature, and that descendants of stars originating in the Li dip and low-luminosity red giants are ideal tests of this channel.
THE REDSHIFT DISTRIBUTION OF GIANT ARCS IN THE SLOAN GIANT ARCS SURVEY
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bayliss, Matthew B.; Gladders, Michael D.; Koester, Benjamin P.
2011-01-20
We measure the redshift distribution of a sample of 28 giant arcs discovered as a part of the Sloan Giant Arcs Survey. Gemini/GMOS-North spectroscopy provides precise redshifts for 24 arcs, and 'redshift desert' constrains for the remaining 4 arcs. This is a direct measurement of the redshift distribution of a uniformly selected sample of bright giant arcs, which is an observable that can be used to inform efforts to predict giant arc statistics. Our primary giant arc sample has a median redshift z = 1.821 and nearly two-thirds of the arcs, 64%, are sources at z {approx}> 1.4, indicating thatmore » the population of background sources that are strongly lensed into bright giant arcs resides primarily at high redshift. We also analyze the distribution of redshifts for 19 secondary strongly lensed background sources that are not visually apparent in Sloan Digital Sky Survey imaging, but were identified in deeper follow-up imaging of the lensing cluster fields. Our redshift sample for the secondary sources is not spectroscopically complete, but combining it with our primary giant arc sample suggests that a large fraction of all background galaxies that are strongly lensed by foreground clusters reside at z {approx}> 1.4. Kolmogorov-Smirnov tests indicate that our well-selected, spectroscopically complete primary giant arc redshift sample can be reproduced with a model distribution that is constructed from a combination of results from studies of strong-lensing clusters in numerical simulations and observational constraints on the galaxy luminosity function.« less
EFFECTS OF DYNAMICAL EVOLUTION OF GIANT PLANETS ON SURVIVAL OF TERRESTRIAL PLANETS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Matsumura, Soko; Ida, Shigeru; Nagasawa, Makiko
2013-04-20
The orbital distributions of currently observed extrasolar giant planets allow marginally stable orbits for hypothetical, terrestrial planets. In this paper, we propose that many of these systems may not have additional planets on these ''stable'' orbits, since past dynamical instability among giant planets could have removed them. We numerically investigate the effects of early evolution of multiple giant planets on the orbital stability of the inner, sub-Neptune-like planets which are modeled as test particles, and determine their dynamically unstable region. Previous studies have shown that the majority of such test particles are ejected out of the system as a resultmore » of close encounters with giant planets. Here, we show that secular perturbations from giant planets can remove test particles at least down to 10 times smaller than their minimum pericenter distance. Our results indicate that, unless the dynamical instability among giant planets is either absent or quiet like planet-planet collisions, most test particles down to {approx}0.1 AU within the orbits of giant planets at a few AU may be gone. In fact, out of {approx}30% of survived test particles, about three quarters belong to the planet-planet collision cases. We find a good agreement between our numerical results and the secular theory, and present a semi-analytical formula which estimates the dynamically unstable region of the test particles just from the evolution of giant planets. Finally, our numerical results agree well with the observations, and also predict the existence of hot rocky planets in eccentric giant planet systems.« less
Assessing vulnerability of giant pandas to climate change in the Qinling Mountains of China.
Li, Jia; Liu, Fang; Xue, Yadong; Zhang, Yu; Li, Diqiang
2017-06-01
Climate change might pose an additional threat to the already vulnerable giant panda ( Ailuropoda melanoleuca ). Effective conservation efforts require projections of vulnerability of the giant panda in facing climate change and proactive strategies to reduce emerging climate-related threats. We used the maximum entropy model to assess the vulnerability of giant panda to climate change in the Qinling Mountains of China. The results of modeling included the following findings: (1) the area of suitable habitat for giant pandas was projected to decrease by 281 km 2 from climate change by the 2050s; (2) the mean elevation of suitable habitat of giant panda was predicted to shift 30 m higher due to climate change over this period; (3) the network of nature reserves protect 61.73% of current suitable habitat for the species, and 59.23% of future suitable habitat; (4) current suitable habitat mainly located in Chenggu, Taibai, and Yangxian counties (with a total area of 987 km 2 ) was predicted to be vulnerable. Assessing the vulnerability of giant panda provided adaptive strategies for conservation programs and national park construction. We proposed adaptation strategies to ameliorate the predicted impacts of climate change on giant panda, including establishing and adjusting reserves, establishing habitat corridors, improving adaptive capacity to climate change, and strengthening monitoring of giant panda.
Allometry indicates giant eyes of giant squid are not exceptional.
Schmitz, Lars; Motani, Ryosuke; Oufiero, Christopher E; Martin, Christopher H; McGee, Matthew D; Gamarra, Ashlee R; Lee, Johanna J; Wainwright, Peter C
2013-02-18
The eyes of giant and colossal squid are among the largest eyes in the history of life. It was recently proposed that sperm whale predation is the main driver of eye size evolution in giant squid, on the basis of an optical model that suggested optimal performance in detecting large luminous visual targets such as whales in the deep sea. However, it is poorly understood how the eye size of giant and colossal squid compares to that of other aquatic organisms when scaling effects are considered. We performed a large-scale comparative study that included 87 squid species and 237 species of acanthomorph fish. While squid have larger eyes than most acanthomorphs, a comparison of relative eye size among squid suggests that giant and colossal squid do not have unusually large eyes. After revising constants used in a previous model we found that large eyes perform equally well in detecting point targets and large luminous targets in the deep sea. The eyes of giant and colossal squid do not appear exceptionally large when allometric effects are considered. It is probable that the giant eyes of giant squid result from a phylogenetically conserved developmental pattern manifested in very large animals. Whatever the cause of large eyes, they appear to have several advantages for vision in the reduced light of the deep mesopelagic zone.
Multiple Giant Coronary Artery Aneurysms
Marla, Rammohan; Ebel, Rachel; Crosby, Marcus; Almassi, G. Hossein
2009-01-01
Coronary artery aneurysms are rare, and giant coronary artery aneurysms are even rarer. We describe a patient who had giant coronary aneurysms of the right, left circumflex, and left anterior descending coronary arteries. The aneurysms were successfully treated with surgical intervention. To the best of our knowledge, ours is the 1st report of giant aneurysms involving all 3 major coronary arteries. PMID:19568397
78 FR 77362 - Atlantic Highly Migratory Species; Atlantic Bluefin Tuna Fisheries
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-23
... large medium or giant BFT to two large medium or giant BFT for the January 2014 subquota period ((i.e... starting on January 1 would be the default retention limit of one large medium or giant BFT (measuring 73... adjusted the General category limit from the default level of one large medium or giant BFT to two large...
76 FR 76900 - Atlantic Highly Migratory Species; Atlantic Bluefin Tuna Fisheries
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-09
... retention limit of one large medium or giant BFT (measuring 73 inches (185 cm) CFL) or greater per vessel... level of one large medium or giant BFT as follows: Two large medium or giant BFT for January (75 FR 79309, December 20, 2010); three large medium or giant BFT for June through August (76 FR 32086, June 3...
75 FR 79309 - Atlantic Highly Migratory Species; Atlantic Bluefin Tuna Fisheries
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2010-12-20
... limit of one large medium or giant BFT (measuring 73 inches (185 cm) CFL) or greater per vessel per day... adjusted the General category limit from the default level of one large medium or giant BFT as follows: Two large medium or giant BFT for January (74 FR 68709, December 29, 2009), and three large medium or giant...
NASA Astrophysics Data System (ADS)
Sneden, Christopher; Kraft, Robert P.; Prosser, Charles F.; Langer, G. E.
1991-12-01
Oxygen, iron, vanadium, and scandium abundances are derived for very metal-poor giants in the globular clusters M92 and M15, and giants of comparable metallicity in the local halo field. The forbidden O I line dublet (6300, 6363) and nearby metallic lines in spectra are analyzed using line analysis and spectral synthesis codes. The Fe/H abundance for M92 is estimated at -2.25 +/-0.02 based on nine giants with a range of 500 K in effective temperature. No evidence for star-to-star variations in the Fe/H abundance was found. O-rich and O-poor stars appear intermixed in the H-R diagram. O - N nuclear synthesis and mixing to the surface are proposed as the best explanation for the low-oxygen giants. The nitrogen abundances obtained earlier for nine of the ten halo field giants in this sample are incompatible with the very large nitrogen abundances expected of the O/Fe abundance of about + 1.2 in halo field subdwarfs, as found by Abia and Rebolo (1989), and not more than 0.6 in halo giants, as found in this and other studies.
Establishment and cryopreservation of a giant panda skeletal muscle-derived cell line.
Yu, Fang-Jian; Zeng, Chang-Jun; Zhang, Yan; Wang, Cheng-Dong; Xiong, Tie-Yi; Fang, Sheng-Guo; Zhang, He-Min
2015-06-01
The giant panda Ailuropoda melanoleuca is an endangered species and is a symbol for wildlife conservation. Although efforts have been made to protect this rare and endangered species through breeding and conservative biology, the long-term preservation of giant panda genome resources (gametes, tissues, organs, genomic libraries, etc.) is still a practical option. In this study, the giant panda skeletal muscle-derived cell line was successfully established via primary explants culture and cryopreservation techniques. The population doubling time of giant panda skeletal cells was approximately 33.8 h, and this population maintained a high cell viability before and after cryopreservation (95.6% and 90.7%, respectively). The two skeletal muscle-specific genes SMYD1 and MYF6 were expressed and detected by RT-PCR in the giant panda skeletal muscle-derived cell line. Karyotyping analysis revealed that the frequencies of giant panda skeletal muscle cells showing a chromosome number of 2n=42 ranged from 90.6∼94.2%. Thus, the giant panda skeletal muscle-derived cell line provides a vital resource and material platform for further studies and is likely to be useful for the protection of this rare and endangered species.
The association between giant hydrocele and depression in a rural clinic in Nigeria.
Dienye, Paul O; Gbeneol, Precious K; Akani, Alexander B
2011-09-01
One of the dreaded disfiguring disease conditions among the Andoni tribesmen in the Nigerian Niger delta region is hydrocele, especially when its size is large (giant hydrocele) and it cannot be concealed. This case-control study was designed to evaluate the prevalence of depression among patients with giant hydrocele presenting to Bethesda Clinic Ngo, Andoni, Nigeria. A total of 52 patients were recruited into this study: 26 in the giant hydrocele group and 26 in the control group. Their age range was 23 to 78 years, with a mean age of 53.4 ± 15.5 years for the giant hydrocele group and 53.6 ± 14.2 years for the control group. The difference between the prevalence of depression among patients that presented with giant hydrocele (61.54%) and the controls (15.38%) was statistically significant (p = .0015). The authors conclude that depression is common among patients with giant hydrocele when compared with patients with other disease conditions.
Cell-sized asymmetric lipid vesicles facilitate the investigation of asymmetric membranes
NASA Astrophysics Data System (ADS)
Kamiya, Koki; Kawano, Ryuji; Osaki, Toshihisa; Akiyoshi, Kazunari; Takeuchi, Shoji
2016-09-01
Asymmetric lipid giant vesicles have been used to model the biochemical reactions in cell membranes. However, methods for producing asymmetric giant vesicles lead to the inclusion of an organic solvent layer that affects the mechanical and physical characteristics of the membrane. Here we describe the formation of asymmetric giant vesicles that include little organic solvent, and use them to investigate the dynamic responses of lipid molecules in the vesicle membrane. We formed the giant vesicles via the inhomogeneous break-up of a lipid microtube generated by applying a jet flow to an asymmetric planar lipid bilayer. The asymmetric giant vesicles showed a lipid flip-flop behaviour in the membrane, superficially similar to the lipid flip-flop activity observed in apoptotic cells. In vitro synthesis of membrane proteins into the asymmetric giant vesicles revealed that the lipid asymmetry in bilayer membranes improves the reconstitution ratio of membrane proteins. Our asymmetric giant vesicles will be useful in elucidating lipid-lipid and lipid-membrane protein interactions involved in the regulation of cellular functions.
SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation
Takahashi, Yutaka; Carpino, Nick; Cross, James C.; Torres, Miguel; Parganas, Evan; Ihle, James N.
2003-01-01
Suppressor of cytokine signaling 3 (SOCS3) binds cytokine receptors and thereby suppresses cytokine signaling. Deletion of SOCS3 causes an embryonic lethality that is rescued by a tetraploid rescue approach, demonstrating an essential role in placental development and a non-essential role in embryo development. Rescued SOCS3-deficient mice show a perinatal lethality with cardiac hypertrophy. SOCS3-deficient placentas have reduced spongiotrophoblasts and increased trophoblast secondary giant cells. Enforced expression of SOCS3 in a trophoblast stem cell line (Rcho-1) suppresses giant cell differentiation. Conversely, SOCS3-deficient trophoblast stem cells differentiate more readily to giant cells in culture, demonstrating that SOCS3 negatively regulates trophoblast giant cell differentiation. Leukemia inhibitory factor (LIF) promotes giant cell differentiation in vitro, and LIF receptor (LIFR) deficiency results in loss of giant cell differentiation in vivo. Finally, LIFR deficiency rescues the SOCS3-deficient placental defect and embryonic lethality. The results establish SOCS3 as an essential regulator of LIFR signaling in trophoblast differentiation. PMID:12554639
Halstead, Brian J.; Wood, Dustin A.; Bowen, Lizabeth; Waters, Shannon C.; Vandergast, Amy G.; Ersan, Julia S.; Skalos, Shannon M.; Casazza, Michael L.
2017-09-28
Detecting populations of rare or cryptic species is essential for their conservation. For species like giant gartersnakes (Thamnophis gigas), conventional survey methods can be expensive and inefficient. These sampling difficulties might be overcome by modern techniques that detect deoxyribonucleic acid (DNA) shed by organisms into the environment (eDNA). We evaluated the efficacy of detecting giant gartersnake eDNA in water samples from the laboratory and at locations with known giant gartersnake populations in the Sacramento Valley of California, and failed to detect giant gartersnake DNA in most laboratory and all field samples. Aspects of giant gartersnake biology—such as highly keratinized skin and spending extensive time in the terrestrial environment, as well as hot, sunny, and turbid conditions in wetlands and canals of the Sacramento Valley—likely contributed to low detection probabilities. Although detection of eDNA shows promise under many conditions, further development is needed before sampling for eDNA is a viable option for detecting giant gartersnake populations.
Reactor vibration reduction based on giant magnetostrictive materials
NASA Astrophysics Data System (ADS)
Rongge, Yan; Weiying, Liu; Yuechao, Wu; Menghua, Duan; Xiaohong, Zhang; Lihua, Zhu; Ling, Weng; Ying, Sun
2017-05-01
The vibration of reactors not only produces noise pollution, but also affects the safe operation of reactors. Giant magnetostrictive materials can generate huge expansion and shrinkage deformation in a magnetic field. With the principle of mutual offset between the giant magnetostrictive force produced by the giant magnetostrictive material and the original vibration force of the reactor, the vibration of the reactor can be reduced. In this paper, magnetization and magnetostriction characteristics in silicon steel and the giant magnetostrictive material are measured, respectively. According to the presented magneto-mechanical coupling model including the electromagnetic force and the magnetostrictive force, reactor vibration is calculated. By comparing the vibration of the reactor with different inserted materials in the air gaps between the reactor cores, the vibration reduction effectiveness of the giant magnetostrictive material is validated.
In Situ Probe Science at Saturn
NASA Astrophysics Data System (ADS)
Atkinson, David H.; Lunine, Jonathan I.; Simon-Miller, Amy A.; Atreya, Sushil K.; Brinckerhoff, William B.; Colaprete, Anthony; Coustenis, Athena; Fletcher, Leigh N.; Guillot, Tristan; Lebreton, Jean-Pierre; Mahaffy, Paul; Mousis, Olivier; Orton, Glenn S.; Reh, Kim; Spilker, Linda J.; Spilker, Thomas R.; Webster, Chris R.
2014-05-01
A fundamental goal of solar system exploration is to understand the origin of the solar system, the initial stages, conditions, and processes by which the solar system formed, how the formation process was initiated, and the nature of the interstellar seed material from which the solar system was born. Key to understanding solar system formation and subsequent dynamical and chemical evolution is the origin and evolution of the giant planets and their atmospheres. Several theories have been put forward to explain the process of solar system formation, and the origin and evolution of the giant planets and their atmospheres. Each theory offers quantifiable predictions of the abundances of noble gases He, Ne, Ar, Kr, and Xe, and abundances of key isotopic ratios 4He/3He, D/H, 15N/14N, 18O/16O, and 13C/12C. Detection of certain disequilibrium species, diagnostic of deeper internal processes and dynamics of the atmosphere, would also help discriminate between competing theories. Many of the key atmospheric constituents needed to discriminate between alternative theories of giant planet formation and chemical evolution are either spectrally inactive or primarily located in the deeper atmosphere inaccessible to remote sensing from Earth, flyby, or orbiting spacecraft. Abundance measurements of these key constituents, including the two major molecular carriers of carbon, methane and carbon monoxide (neither of which condense in Saturn's atmosphere), sulfur which is expected to be well-mixed below the 4 to 5-bar ammonium hydrosulfide (NH4SH) cloud, and gradients of nitrogen below the NH4SH cloud and oxygen in the upper layers of the H2O and H2O-NH4 solution cloud, must be made in situ and can only be achieved by an entry probe descending through 10 bars. Measurements of the critical abundance profiles of these key constituents into the deeper well-mixed atmosphere must be complemented by measurements of the profiles of atmospheric structure and dynamics at high vertical resolution that also require in situ exploration. The atmospheres of the giant planets can also serve as laboratories to better understand the atmospheric chemistries, dynamics, processes, and climates on all planets in the solar system including Earth, and offer a context and provide a ground truth for exoplanets and exoplanetary systems. Additionally, Giant planets have long been thought to play a critical role in the development of potentially habitable planetary systems. In the context of giant planet science provided by the Galileo, Juno, and Cassini missions to Jupiter and Saturn, a small, relatively shallow Saturn probe capable of measuring abundances and isotopic ratios of key atmospheric constituents, and atmospheric structure including pressures, temperatures, dynamics, and cloud locations and properties not accessible by remote sensing can serve to test competing theories of solar system and giant planet origin, chemical, and dynamical evolution. Acknowledgements This research was carried out in part at the Jet Propulsion Laboratory, California Institute of Technology, under contract with NASA. Copyright 2013 California Institute of Technology. U.S. Government sponsorship acknowledged. O. Mousis acknowledges support from CNES.
USDA-ARS?s Scientific Manuscript database
Giant reed (Arundo donax L.) also known as giant cane or carrizo cane, is an exotic perennial grass that has infested over 60,000 hectares along riparian corridors in the southwestern U.S. The most severe infestations are in the Lower Rio Grande Basin, where giant reed along the Rio Grande and Mexic...
Giant cell arteritis mimicking a testicular tumour.
Sundaram, S; Smith, D H
2001-07-01
Giant cell arteritis involving the testis was identified incidentally upon orchidectomy of a right testicular mass. The mass looked like a malignant process on ultrasound. The patient also had generalised disease and was treated appropriately. Giant cell arteritis involving the bladder, prostate, uterus, and adnexa have been described before. To our knowledge, this is the first described case of giant cell arteritis affecting the testis.
Unusual Giant Prostatic Urethral Calculus
Bello, A.; Maitama, H. Y.; Mbibu, N. H.; Kalayi, G. D.; Ahmed, A.
2010-01-01
Giant vesico-prostatic urethral calculus is uncommon. Urethral stones rarely form primarily in the urethra, and they are usually associated with urethral strictures, posterior urethral valve or diverticula. We report a case of a 32-year-old man with giant vesico-prostatic (collar-stud) urethral stone presenting with sepsis and bladder outlet obstruction. The clinical presentation, management, and outcome of the giant prostatic urethral calculus are reviewed. PMID:22091328
NASA Astrophysics Data System (ADS)
Frelikh, Renata; Murray-Clay, Ruth
2018-04-01
We report on our recent theoretical work, where we suggest that a protoplanetary disk dynamical instability may have played a crucial role in determining the atmospheric size of the solar system’s ice giants. In contrast to the gas giants, the intermediate-size ice giants never underwent runaway gas accretion in a full gas disk. However, as their substantial core masses are comparable to those of the gas giants, they would have gone runaway, given enough time. In the standard scenario, the ice giants stay at roughly their current size for most of the disk lifetime, undergoing period of slow gas accretion onto ~full-sized cores that formed early-on. The gas disk dissipates before the ice giants accumulate too much gas, but we believe this is fine tuned. A considerable amount of solids is observed in outer disks in mm-to-cm sized particles (pebbles). Assisted by gas drag, these pebbles rapidly accrete onto cores. This would cause the growing ice giants to exceed their current core masses, and quickly turn into gas giants. To resolve this problem, we propose that Uranus and Neptune stayed small for the bulk of the disk lifetime. They only finished their core and atmospheric growth in a short timeframe just as the disk gas dissipated, accreting most of their gas from a disk depleted to ~1% of its original mass. The ice giants have atmospheric mass fractions comparable to the disk gas-to-solid ratio of this depleted disk. This coincides with a disk dynamical upheaval onset by the depletion of gas. We propose that the cores started growing closer-in, where they were kept small by proximity to Jupiter and Saturn. As the gas cleared, the cores were kicked out by the gas giants. Then, they finished their core growth and accreted their atmospheres from the remaining, sparse gas at their current locations. We predict that the gas giants may play a key role in forming intermediate-size atmospheres in the outer disk.
2000-11-28
During pre-pack and fit check in the Operations and Checkout Building, STS-97 Mission Specialist Marc Garneau waves after getting his helmet on. Garneau is with the Canadian Space Agency. Mission STS-97 is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST
2000-11-27
After arriving at the Shuttle Landing Facility, the STS-97 crew gather to address the media. At the microphone is Pilot Michael Bloomfield. Behind him can be seen Mission Specialists Joseph Tanner and Carlos Noriega. Mission STS-97 is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST
2000-10-31
KENNEDY SPACE CENTER, Fla. -- Perched atop the Mobile Launcher Platform, Space Shuttle Endeavour approaches the gate to Launch Pad 39B. To the right of the pad is a 290-foot tall water tower. Endeavour is scheduled to be launched Nov. 30 at 10:01 p.m. EST on mission STS-97, the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections
2000-10-31
KENNEDY SPACE CENTER, Fla. -- Perched atop the Mobile Launcher Platform, Space Shuttle Endeavour approaches the gate to Launch Pad 39B. To the right of the pad is a 290-foot tall water tower. Endeavour is scheduled to be launched Nov. 30 at 10:01 p.m. EST on mission STS-97, the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections
2000-11-28
STS-97 Mission Specialist Marc Garneau gets help with his boots from suit technician Tommy McDonald during pre-pack and fit check. Garneau is with the Canadian Space Agency. Mission STS-97 is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST
STS-97 (4A) EVA training in NBL pool
2000-10-23
JSC2000-07082 (October 2000)--- Wearing a training version of the shuttle extravehicular mobility unit (EMU) space suit, astronaut Joseph R. Tanner, STS-97 mission specialist, simulates a space walk underwater in the giant Neutral Buoyancy Laboratory (NBL). Tanner was there, along with astronaut Carlos I. Noriega, to rehearse one of three scheduled space walks to make additions to the International Space Station (ISS). The five-man crew in early December will deliver the P6 Integrated Truss Segment, which includes the first US Solar arrays and a power distribution system.
STS-97 Mission Specialist Tanner during pre-pack and fit check
NASA Technical Reports Server (NTRS)
2000-01-01
STS-97 Mission Specialist Joseph Tanner gets help with his boots from suit technician Erin Canlon during check pre-pack and fit check. Mission STS-97 is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST.
STS-97 Mission Specialist Noriega during pre-pack and fit check
NASA Technical Reports Server (NTRS)
2000-01-01
STS-97 Mission Specialist Carlos Noriega gets help with his boots from suit technician Shelly Grick-Agrella during pre-pack and fit check. Mission STS-97 is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST.
Spectral discrimination of giant reed (Arundo donax L.): A seasonal study in riparian areas
NASA Astrophysics Data System (ADS)
Fernandes, Maria Rosário; Aguiar, Francisca C.; Silva, João M. N.; Ferreira, Maria Teresa; Pereira, José M. C.
2013-06-01
The giant reed (Arundo donax L.) is amongst the one hundred worst invasive alien species of the world, and it is responsible for biodiversity loss and failure of ecosystem functions in riparian habitats. In this work, field spectroradiometry was used to assess the spectral separability of the giant reed from the adjacent vegetation and from the common reed, a native similar species. The study was conducted at different phenological periods and also for the giant reed stands regenerated after mechanical cutting (giant reed_RAC). A hierarchical procedure using Kruskal-Wallis test followed by Classification and Regression Trees (CART) was used to select the minimum number of optimal bands that discriminate the giant reed from the adjacent vegetation. A new approach was used to identify sets of wavelengths - wavezones - that maximize the spectral separability beyond the minimum number of optimal bands. Jeffries Matusita and Bhattacharya distance were used to evaluate the spectral separability using the minimum optimal bands and in three simulated satellite images, namely Landsat, IKONOS and SPOT. Giant reed was spectrally separable from the adjacent vegetation, both at the vegetative and the senescent period, exception made to the common reed at the vegetative period. The red edge region was repeatedly selected, although the visible region was also important to separate the giant reed from the herbaceous vegetation and the mid infrared region to the discrimination from the woody vegetation. The highest separability was obtained for the giant reed_RAC stands, due to its highly homogeneous, dense and dark-green stands. Results are discussed by relating the phenological, morphological and structural features of the giant reed stands and the adjacent vegetation with their optical traits. Weaknesses and strengths of the giant reed spectral discrimination are highlighted and implications of imagery selection for mapping purposes are argued based on present results.
METAL-POOR LITHIUM-RICH GIANTS IN THE RADIAL VELOCITY EXPERIMENT SURVEY
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ruchti, Gregory R.; Fulbright, Jon P.; Wyse, Rosemary F. G.
We report the discovery of eight lithium-rich field giants found in a high-resolution spectroscopic sample of over 700 metal-poor stars ([Fe/H] < -0.5) selected from the Radial Velocity Experiment survey. The majority of the Li-rich giants in our sample are very metal-poor ([Fe/H] {approx}< -1.9), and have a Li abundance (in the form of {sup 7}Li), A(Li) = log (n(Li)/n(H)) + 12, between 2.30 and 3.63, well above the typical upper red giant branch (RGB) limit, A(Li) < 0.5, while two stars, with A(Li) {approx} 1.7-1.8, show similar lithium abundances to normal giants at the same gravity. We further includedmore » two metal-poor, Li-rich globular cluster giants in our sample, namely the previously discovered M3-IV101 and newly discovered (in this work) M68-A96. This comprises the largest sample of metal-poor Li-rich giants to date. We performed a detailed abundance analysis of all stars, finding that the majority of our sample stars have elemental abundances similar to that of Li-normal halo giants. Although the evolutionary phase of each Li-rich giant cannot be definitively determined, the Li-rich phase is likely connected to extra mixing at the RGB bump or early asymptotic giant branch that triggers cool bottom processing in which the bottom of the outer convective envelope is connected to the H-burning shell in the star. The surface of a star becomes Li-enhanced as {sup 7}Be (which burns to {sup 7}Li) is transported to the stellar surface via the Cameron-Fowler mechanism. We discuss and discriminate among several models for the extra mixing that can cause Li production, given the detailed abundances of the Li-rich giants in our sample.« less
Impacts of temperature on giant panda habitat in the north Minshan Mountains.
Liu, Gang; Guan, Tianpei; Dai, Qiang; Li, Huixin; Gong, Minghao
2016-02-01
Understanding the impacts of meteorological factors on giant pandas is necessary for future conservation measures in response to global climate change. We integrated temperature data with three main habitat parameters (elevation, vegetation type, and bamboo species) to evaluate the influence of climate change on giant panda habitat in the northern Minshan Mountains using a habitat assessment model. Our study shows that temperature (relative importance = 25.1%) was the second most important variable influencing giant panda habitat excepting the elevation. There was a significant negative correlation between temperature and panda presence (ρ = -0.133, P < 0.05), and the temperature range preferred by giant pandas within the study area was 18-21°C, followed by 15-17°C and 22-24°C. The overall suitability of giant panda habitats will increase by 2.7%, however, it showed a opposite variation patterns between the eastern and northwestern region of the study area. Suitable and subsuitable habitats in the northwestern region of the study area, which is characterized by higher elevation and latitude, will increase by 18007.8 hm(2) (9.8% habitat suitability), while the eastern region will suffer a decrease of 9543.5 hm(2) (7.1% habitat suitability). Our results suggest that increasing areas of suitable giant panda habitat will support future giant panda expansion, and food shortage and insufficient living space will not arise as problems in the northwest Minshan Mountains, which means that giant pandas can adapt to climate change, and therefore may be resilient to climate change. Thus, for the safety and survival of giant pandas in the Baishuijiang Reserve, we propose strengthening the giant panda monitoring program in the west and improving the integrity of habitats to promote population dispersal with adjacent populations in the east.
Formation of terrestrial planets in eccentric and inclined giant planet systems
NASA Astrophysics Data System (ADS)
Sotiriadis, Sotiris; Libert, Anne-Sophie; Raymond, Sean N.
2018-06-01
Aims: Evidence of mutually inclined planetary orbits has been reported for giant planets in recent years. Here we aim to study the impact of eccentric and inclined massive giant planets on the terrestrial planet formation process, and investigate whether it can possibly lead to the formation of inclined terrestrial planets. Methods: We performed 126 simulations of the late-stage planetary accretion in eccentric and inclined giant planet systems. The physical and orbital parameters of the giant planet systems result from n-body simulations of three giant planets in the late stage of the gas disc, under the combined action of Type II migration and planet-planet scattering. Fourteen two- and three-planet configurations were selected, with diversified masses, semi-major axes (resonant configurations or not), eccentricities, and inclinations (including coplanar systems) at the dispersal of the gas disc. We then followed the gravitational interactions of these systems with an inner disc of planetesimals and embryos (nine runs per system), studying in detail the final configurations of the formed terrestrial planets. Results: In addition to the well-known secular and resonant interactions between the giant planets and the outer part of the disc, giant planets on inclined orbits also strongly excite the planetesimals and embryos in the inner part of the disc through the combined action of nodal resonance and the Lidov-Kozai mechanism. This has deep consequences on the formation of terrestrial planets. While coplanar giant systems harbour several terrestrial planets, generally as massive as the Earth and mainly on low-eccentric and low-inclined orbits, terrestrial planets formed in systems with mutually inclined giant planets are usually fewer, less massive (<0.5 M⊕), and with higher eccentricities and inclinations. This work shows that terrestrial planets can form on stable inclined orbits through the classical accretion theory, even in coplanar giant planet systems emerging from the disc phase.
Huang, Jie; Li, Yu-Zhi; Du, Lian-Ming; Yang, Bo; Shen, Fu-Jun; Zhang, He-Min; Zhang, Zhi-He; Zhang, Xiu-Yue; Yue, Bi-Song
2015-02-07
The giant panda (Ailuropoda melanoleuca) is a critically endangered species endemic to China. Microsatellites have been preferred as the most popular molecular markers and proven effective in estimating population size, paternity test, genetic diversity for the critically endangered species. The availability of the giant panda complete genome sequences provided the opportunity to carry out genome-wide scans for all types of microsatellites markers, which now opens the way for the analysis and development of microsatellites in giant panda. By screening the whole genome sequence of giant panda in silico mining, we identified microsatellites in the genome of giant panda and analyzed their frequency and distribution in different genomic regions. Based on our search criteria, a repertoire of 855,058 SSRs was detected, with mono-nucleotides being the most abundant. SSRs were found in all genomic regions and were more abundant in non-coding regions than coding regions. A total of 160 primer pairs were designed to screen for polymorphic microsatellites using the selected tetranucleotide microsatellite sequences. The 51 novel polymorphic tetranucleotide microsatellite loci were discovered based on genotyping blood DNA from 22 captive giant pandas in this study. Finally, a total of 15 markers, which showed good polymorphism, stability, and repetition in faecal samples, were used to establish the novel microsatellite marker system for giant panda. Meanwhile, a genotyping database for Chengdu captive giant pandas (n = 57) were set up using this standardized system. What's more, a universal individual identification method was established and the genetic diversity were analysed in this study as the applications of this marker system. The microsatellite abundance and diversity were characterized in giant panda genomes. A total of 154,677 tetranucleotide microsatellites were identified and 15 of them were discovered as the polymorphic and stable loci. The individual identification method and the genetic diversity analysis method in this study provided adequate material for the future study of giant panda.
Giant cell arteritis is a disorder that causes inflammation of your arteries, usually in the scalp, neck, and arms. ... arteries, which keeps blood from flowing well. Giant cell arteritis often occurs with another disorder called polymyalgia ...
Eliava, Shalva S; Filatov, Yuri M; Yakovlev, Sergei B; Shekhtman, Oleg D; Kheireddin, Ali S; Sazonov, Ilya A; Sazonova, Olga B; Okishev, Dmitry N
2010-06-01
Microsurgical treatment of large and giant paraclinoid internal carotid artery (ICA) aneurysms often requires the use of the retrograde suction decompression (RSD) technique to facilitate clipping. Surgical results, functional outcomes at discharge, and technique limitations based on single institution series are presented. Between 1996 and 2009, eighty-three consecutive patients (19 to 68 years, mean 45.5 ± 9.9 years), predominantly women (69 women and 14 men) with large (23 patients, 27.7%) or giant (60 patients, 72.3%) paraclinoid aneurysms were surgically treated with the RSD technique performed by the neck route (62 patients, 74.4%) or later on, by endovascular means (21 patients, 25.3%). Patients were admitted after hemorrhage (48 patients, 57.9%), pseudotumor course (28 patients, 33.7%), mixed symptoms (5 patients, 6%), or asymptomatic (2 patients, 2.4%). In most RSD surgeries (90.4%) aneurysms were successfully excluded: neck was clipped in 57 patients (68.7%) or clipping with ICA reconstruction was achieved in 18 patients (21.7%). In six patients aneurysms were wrapped with glue (7.2%), trapped in one patient (1.2%), and in one patient, ICA balloon deconstruction was performed (1.2%). Good or excellent results (Glasgow Outcome Scale scores 4-5) at discharge were achieved in 69 patients (83.1%), 11 patients (13.3%) remained severely disabled (Glasgow Outcome Scale 3), and 3 patients died (3.6%). Surgical clipping with the RSD method remains a treatment of choice with acceptable outcomes for patients not amenable for endovascular treatment. Copyright © 2010 Elsevier Inc. All rights reserved.
Grogan, T M; Richter, L C; Payne, C M; Rangel, C S
1985-09-01
In contrast to previous accounts of signet-ring lymphoma as a B-cell neoplasm, we report a case of signet-ring, large-cell lymphoma of T-cell lineage. Immunologic and ultrastructural studies were performed on a subcutaneous mass noted initially, as well as on an enlarged lymph node that developed later, in a 69-year-old man. Immunologic assessment indicated strong expression of T-helper antigen (Leu 3a + b), universal T-antigens (Leu 1, 5), and Ia. There was an absence of T-suppressor/cytotoxic antigen (Leu 2a), universal T-antigens (Leu 4, 9), and immunoglobulin light and heavy chains. Collectively, these findings indicate a mature T-cell lymphoma of T-helper type in an activated (Ia+) state. In contrast to previous reports of T-cell and Ia occurring solely as surface antigens, we demonstrated pools of cytoplasmic Leu 1, 3, 5 and Ia that displaced the nucleus. The ultrastructure of the giant cytoplasmic vacuoles was identical to the microvesicle-containing vacuoles reported in signet-ring cell lymphomas of B-cell lineage. In our case of T-cell lineage, we found substantial evidence of endocytosis by the neoplastic cells and numerous giant multivesicular bodies. The pools of cytoplasmic T and Ia antigens may result from abnormal internalization of surface T-antigens or the sequestration of T-antigen-containing Golgi-derived vesicles. Our combined immunologic and ultrastructural findings suggest that aberrant membrane recycling may be the common denominator of signet-ring formation in both B- and T-cell signet-ring lymphomas.
Kumar, Anoop; Sherlin, Herald J; Ramani, Pratibha; Natesan, Anuja; Premkumar, Priya
2015-01-01
Multinucleated giant cells (MNCs) form an integral part of numerous bone and soft tissue tumors, tumor-like lesions and are often associated with granulomas of immunological and nonimmunological origin. The presence of various types of giant cells depends on the lesions in which they are present which are difficult to be diagnosed under routine histological techniques. Immunohistochemistry can be used for a better diagnosis and understanding of the origin of various giant cells using various markers of immune response like human leukocyte antigen-DR (HLA-DR) and those expressed on monocytes and macrophages like CD 68 and leukocyte common antigen (LCA). The study group consisted of 10 cases of giant cell tumor (GCT) of long bones, tuberculous granuloma, and giant cell granuloma to evaluate and analyze the expression pattern of LCA, CD 68, and HLA-DR in various giant cell lesions. Strong expression of CD 68 was observed in 80% of the lesions, strong and moderate expression of CD 45 observed in 70% of the lesions among and within the groups. In contrast, HLA-DR demonstrated negative expression in 80% of cases except for tuberculous granuloma where all the 10 cases showed moderate to strong immunoreactivity. CD 68 and CD 45 expression was found in central giant cell granuloma, peripheral giant cell granuloma and GCT, suggesting the origin from mononuclear phagocyte system and considering their clinical behavior of osteoclast type. High expressivity of HLA-DR in tuberculous granulomas which is an essential factor for presentation of the microbial antigen to CD 4 helper cells thus reassuring the fact that they are up-regulated in response to infection.
Virome comparisons in wild-diseased and healthy captive giant pandas.
Zhang, Wen; Yang, Shixing; Shan, Tongling; Hou, Rong; Liu, Zhijian; Li, Wang; Guo, Lianghua; Wang, Yan; Chen, Peng; Wang, Xiaochun; Feng, Feifei; Wang, Hua; Chen, Chao; Shen, Quan; Zhou, Chenglin; Hua, Xiuguo; Cui, Li; Deng, Xutao; Zhang, Zhihe; Qi, Dunwu; Delwart, Eric
2017-08-07
The giant panda (Ailuropoda melanoleuca) is a vulnerable mammal herbivore living wild in central China. Viral infections have become a potential threat to the health of these endangered animals, but limited information related to these infections is available. Using a viral metagenomic approach, we surveyed viruses in the feces, nasopharyngeal secretions, blood, and different tissues from a wild giant panda that died from an unknown disease, a healthy wild giant panda, and 46 healthy captive animals. The previously uncharacterized complete or near complete genomes of four viruses from three genera in Papillomaviridae family, six viruses in a proposed new Picornaviridae genus (Aimelvirus), two unclassified viruses related to posaviruses in Picornavirales order, 19 anelloviruses in four different clades of Anelloviridae family, four putative circoviruses, and 15 viruses belonging to the recently described Genomoviridae family were sequenced. Reflecting the diet of giant pandas, numerous insect virus sequences related to the families Iflaviridae, Dicistroviridae, Iridoviridae, Baculoviridae, Polydnaviridae, and subfamily Densovirinae and plant viruses sequences related to the families Tombusviridae, Partitiviridae, Secoviridae, Geminiviridae, Luteoviridae, Virgaviridae, and Rhabdoviridae; genus Umbravirus, Alphaflexiviridae, and Phycodnaviridae were also detected in fecal samples. A small number of insect virus sequences were also detected in the nasopharyngeal secretions of healthy giant pandas and lung tissues from the dead wild giant panda. Although the viral families present in the sick giant panda were also detected in the healthy ones, a higher proportion of papillomaviruses, picornaviruses, and anelloviruses reads were detected in the diseased panda. This viral survey increases our understanding of eukaryotic viruses in giant pandas and provides a baseline for comparison to viruses detected in future infectious disease outbreaks. The similar viral families detected in sick and healthy giant pandas indicate that these viruses result in commensal infections in most immuno-competent animals.
Zhao, Huabin; Yang, Jian-Rong; Xu, Huailiang; Zhang, Jianzhi
2010-12-01
Although it belongs to the order Carnivora, the giant panda is a vegetarian with 99% of its diet being bamboo. The draft genome sequence of the giant panda shows that its umami taste receptor gene Tas1r1 is a pseudogene, prompting the proposal that the loss of the umami perception explains why the giant panda is herbivorous. To test this hypothesis, we sequenced all six exons of Tas1r1 in another individual of the giant panda and five other carnivores. We found that the open reading frame (ORF) of Tas1r1 is intact in all these carnivores except the giant panda. The rate ratio (ω) of nonsynonymous to synonymous substitutions in Tas1r1 is significantly higher for the giant panda lineage than for other carnivore lineages. Based on the ω change and the observed number of ORF-disrupting substitutions, we estimated that the functional constraint on the giant panda Tas1r1 was relaxed ∼ 4.2 Ma, with its 95% confidence interval between 1.3 and 10 Ma. Our estimate matches the approximate date of the giant panda's dietary switch inferred from fossil records. It is probable that the giant panda's decreased reliance on meat resulted in the dispensability of the umami taste, leading to Tas1r1 pseudogenization, which in turn reinforced its herbivorous life style because of the diminished attraction of returning to meat eating in the absence of Tas1r1. Nonetheless, additional factors are likely involved because herbivores such as cow and horse still retain an intact Tas1r1.
Zhao, Huabin; Yang, Jian-Rong; Xu, Huailiang; Zhang, Jianzhi
2010-01-01
Although it belongs to the order Carnivora, the giant panda is a vegetarian with 99% of its diet being bamboo. The draft genome sequence of the giant panda shows that its umami taste receptor gene Tas1r1 is a pseudogene, prompting the proposal that the loss of the umami perception explains why the giant panda is herbivorous. To test this hypothesis, we sequenced all six exons of Tas1r1 in another individual of the giant panda and five other carnivores. We found that the open reading frame (ORF) of Tas1r1 is intact in all these carnivores except the giant panda. The rate ratio (ω) of nonsynonymous to synonymous substitutions in Tas1r1 is significantly higher for the giant panda lineage than for other carnivore lineages. Based on the ω change and the observed number of ORF-disrupting substitutions, we estimated that the functional constraint on the giant panda Tas1r1 was relaxed ∼4.2 Ma, with its 95% confidence interval between 1.3 and 10 Ma. Our estimate matches the approximate date of the giant panda's dietary switch inferred from fossil records. It is probable that the giant panda's decreased reliance on meat resulted in the dispensability of the umami taste, leading to Tas1r1 pseudogenization, which in turn reinforced its herbivorous life style because of the diminished attraction of returning to meat eating in the absence of Tas1r1. Nonetheless, additional factors are likely involved because herbivores such as cow and horse still retain an intact Tas1r1. PMID:20573776
Fungal cell gigantism during mammalian infection.
Zaragoza, Oscar; García-Rodas, Rocío; Nosanchuk, Joshua D; Cuenca-Estrella, Manuel; Rodríguez-Tudela, Juan Luis; Casadevall, Arturo
2010-06-17
The interaction between fungal pathogens with the host frequently results in morphological changes, such as hyphae formation. The encapsulated pathogenic fungus Cryptococcus neoformans is not considered a dimorphic fungus, and is predominantly found in host tissues as round yeast cells. However, there is a specific morphological change associated with cryptococcal infection that involves an increase in capsule volume. We now report another morphological change whereby gigantic cells are formed in tissue. The paper reports the phenotypic characterization of giant cells isolated from infected mice and the cellular changes associated with giant cell formation. C. neoformans infection in mice resulted in the appearance of giant cells with cell bodies up to 30 microm in diameter and capsules resistant to stripping with gamma-radiation and organic solvents. The proportion of giant cells ranged from 10 to 80% of the total lung fungal burden, depending on infection time, individual mice, and correlated with the type of immune response. When placed on agar, giant cells budded to produce small daughter cells that traversed the capsule of the mother cell at the speed of 20-50 m/h. Giant cells with dimensions that approximated those in vivo were observed in vitro after prolonged culture in minimal media, and were the oldest in the culture, suggesting that giant cell formation is an aging-dependent phenomenon. Giant cells recovered from mice displayed polyploidy, suggesting a mechanism by which gigantism results from cell cycle progression without cell fission. Giant cell formation was dependent on cAMP, but not on Ras1. Real-time imaging showed that giant cells were engaged, but not engulfed by phagocytic cells. We describe a remarkable new strategy for C. neoformans to evade the immune response by enlarging cell size, and suggest that gigantism results from replication without fission, a phenomenon that may also occur with other fungal pathogens.
[Pathological and immunohistochemical analysis of giant cells of pancreas].
Miyake, T; Suda, K; Yamamura, A; Tada, Y
1997-10-01
Multinucleated giant cells in the pancreas (five giant cell carcinomas, a mucinous cystadenocarcinoma attended with many osteoclast-like giant cells, 42 invasive ductal carcinomas and 29 chronic pancreatitises) were examined. Three types of multinucleated giant cell were identified: epithelial type, coexpressive type, mesenchymal type. Epithelial type expressed epithelial markers, such as keratin and EMA in 23 ductal carcinomas. Coexpressive type expressed both epithelial markers and mesenchymal marker vimentin was in four ductal carcinomas. Mesenchymal type expressed mesenchymal markers, vimentin and CD68 in four osteoclastoid type giant cell carcinomas, the mucinous cystadenocarcinoma, six ductal carcinomas and ten chronic pancreatitises. Epithelial and coexpressive type were considered to be epithelial neoplastic origin, those had bizarre appearance and transitional area from definite adenocarcinoma area. Vimentin expression is associated with sarcomatous proliferation. Mesenchymal type was considered to be nonneoplastic and a certain type of macrophage polykaryons.
Giant Pulse Phenomena in a High Gain Erbium Doped Fiber Amplifier
NASA Technical Reports Server (NTRS)
Li, Stephen X.; Merritt, Scott; Krainak, Michael A.; Yu, Anthony
2018-01-01
High gain Erbium Doped Fiber Amplifiers (EDFAs), while revolutionizing optical communications, remain vulnerable to optical damage when unseeded, e.g. due to nonlinear effects that produce random pulses with high peak power, i.e. giant pulses. Giant pulses can damage the components in a high gain EDFA or external components and systems coupled to the EDFA. We explore the conditions under which a reflective, polarization-maintaining (PM), core-pumped high gain EDFA generates giant pulses, provide details on conditions under which normal pulses evolve into giant pulses, and provide results on the transient effects of giant pulses on amplifier's fused-fiber couplers, an effect which we call Fiber Overload Induced Leakage (FOIL). While FOIL's effect on fused-fiber couplers is temporary, its damage to forward pump lasers in a high gain EDFA can be permanent.
Giant Pulse Phenomena in a High Gain Erbium Doped Fiber Amplifier
NASA Technical Reports Server (NTRS)
Li, Stephen X.; Merritt, Scott; Krainak, Michael A.; Yu, Anthony
2018-01-01
High gain Erbium Doped Fiber Amplifiers (EDFAs) are vulnerable to optical damage when unseeded, e.g. due to nonlinear effects that produce random, spontaneous Q-switched (SQS) pulses with high peak power, i.e. giant pulses. Giant pulses can damage either the components within a high gain EDFA or external components and systems coupled to the EDFA. We explore the conditions under which a reflective, polarization-maintaining (PM), core-pumped high gain EDFA generates giant pulses, provide details on the evolution of normal pulses into giant pulses, and provide results on the transient effects of giant pulses on an amplifier's fused-fiber couplers, an effect which we call Fiber Overload Induced Leakage (FOIL). While FOIL's effect on fused-fiber couplers is temporary, its damage to forward pump lasers in a high gain EDFA can be permanent.
Loeffler, I Kati; Howard, JoGayle; Montali, Richard J; Hayek, Lee-Ann; Dubovi, Edward; Zhang, Zhihe; Yan, Qigui; Guo, Wanzhu; Wildt, David E
2007-12-01
Conservation strategies for the giant panda (Ailuropoda melanoleuca) include the development of a self-sustaining ex situ population. This study examined the potential significance of infectious pathogens in giant pandas ex situ. Serologic antibody titers against canine distemper virus (CDV), canine parvovirus (CPV), canine adenovirus (CAV), canine coronavirus (CCV), canine herpesvirus, canine parainfluenza virus (CPIV), Toxoplasma gondii, Neospora caninum, and Leptospira interrogans were measured in 44 samples taken from 19 giant pandas between 1998 and 2003 at the Chengdu Research Base of Giant Panda Breeding in Sichuan, China. Seroassays also included samples obtained in 2003 from eight red pandas (Ailurus fulgens) housed at the same institution. All individuals had been vaccinated with a Chinese canine vaccine that included modified live CDV, CPV, CAV, CCV, and CPIV. Positive antibody titers were found only against CDV, CPV, and T. gondii. Sera were negative for antibodies against the other six pathogens. Results indicate that the quality of the vaccine may not be reliable and that it should not be considered protective or safe in giant pandas and red pandas. Positive antibody titers against T. gondii were found in seven of the 19 giant pandas. The clinical, subclinical, or epidemiologic significance of infection with these pathogens via natural exposure or from modified live vaccines in giant pandas is unknown. Research in this area is imperative to sustaining a viable population of giant pandas and other endangered species.
Electrophysiological Recordings from the Giant Fiber System
Allen, Marcus J
2010-01-01
The giant fiber system (GFS) of Drosophila is a well-characterized neuronal circuit that mediates the escape response in the fly. It is one of the few adult neural circuits from which electrophysiological recordings can be made routinely. This article describes a simple procedure for stimulating the giant fiber neurons directly in the brain of the adult fly and obtaining recordings from the output muscles of the giant fiber system. PMID:20647357
Three cases giant panda attack on human at Beijing Zoo.
Zhang, Peixun; Wang, Tianbing; Xiong, Jian; Xue, Feng; Xu, Hailin; Chen, Jianhai; Zhang, Dianying; Fu, Zhongguo; Jiang, Baoguo
2014-01-01
Panda is regarded as Chinese national treasure. Most people always thought they were cute and just ate bamboo and had never imagined a panda could be vicious. Giant panda attacks on human are rare. There, we present three cases of giant panda attacks on humans at the Panda House at Beijing Zoo from September 2006 to June 2009 to warn people of the giant panda's potentially dangerous behavior.
Non-Small Cell Carcinoma of the Lung With Osteoclast-Like Giant Cells.
Dahm, Hans Helmut
2017-05-01
Carcinomas of the lung with benign osteoclast-like giant cells are rare. A literature search showed only 8 previously reported examples. These tumors resemble a giant cell tumor of bone. Many of these tumors, which occur in most epithelium-containing organs, are composed of an undifferentiated, sarcomatoid component that contains benign osteoclast-like giant cells and a conventional carcinoma. In some tumors the epithelial origin may be revealed by immunohistochemistry only; others lack any evidence of an epithelial component. A 59-year-old man had an inoperable tumor in the upper lobe of the left lung. The tumor did not respond to radiation therapy, and chemotherapy resulted in minimal relief of symptoms. Light microscopy of biopsy samples showed benign osteoclast-like giant cells distributed irregularly between proliferations of undifferentiated medium-sized tumor cells. Approximately one third of the undifferentiated tumor cells were cytokeratin AE1/AE3-positive, and a minor alveolar clear cell component of the tumor was cytokeratin 7-positive. The osteoclast-like giant cells were strongly CD68-positive. The clinical and histologic findings supported the diagnosis of a non-small cell carcinoma of the lung with benign osteoclast-like giant cells. The differential diagnosis is composed of giant cell carcinoma, carcinosarcoma, and mesenchymal tumors of the lung.
Kang, Dongwei; Wang, Xiaorong; Li, Shuang; Li, Junqing
2017-06-15
Artificial restoration is an important way to restore forests, but little is known about its effect on the habitat restoration of the giant panda. In the present study, we investigated the characteristics of artificial forest in the Wanglang Nature Reserve to determine whether through succession it has formed a suitable habitat for the giant panda. We compared artificial forest characteristics with those of natural habitat used by the giant panda. We found that the dominant tree species in artificial forest differed from those in the natural habitat. The artificial forest had lower plant species richness and diversity in the tree and shrub layers than did the latter, and its community structure was characterized by smaller tree and bamboo sizes, and fewer and lower bamboo clumps, but more trees and larger shrub sizes. The typical community collocation of artificial forest was a "Picea asperata + no-bamboo" model, which differs starkly from the giant panda's natural habitat. After several years of restoration, the artificial forest has failed to become a suitable habitat for the giant panda. Therefore, a simple way of planting individual trees cannot restore giant panda habitat; instead, habitat restoration should be based on the habitat requirements of the giant panda.
Subcellular preservation in giant ostracod sperm from an early Miocene cave deposit in Australia
Matzke-Karasz, Renate; Neil, John V.; Smith, Robin J.; Symonová, Radka; Mořkovský, Libor; Archer, Michael; Hand, Suzanne J.; Cloetens, Peter; Tafforeau, Paul
2014-01-01
Cypridoidean ostracods are one of a number of animal taxa that reproduce with giant sperm, up to 10 000 µm in length, but they are the only group to have aflagellate, filamentous giant sperm. The evolution and function of this highly unusual feature of reproduction with giant sperm are currently unknown. The hypothesis of long-term evolutionary persistence of this kind of reproduction has never been tested. We here report giant sperm discovered by propagation phase contrast X-ray synchrotron micro- and nanotomography, preserved in five Miocene ostracod specimens from Queensland, Australia. The specimens belong to the species Heterocypris collaris Matzke-Karasz et al. 2013 (one male and three females) and Newnhamia mckenziana Matzke-Karasz et al. 2013 (one female). The sperm are not only the oldest petrified gametes on record, but include three-dimensional subcellular preservation. We provide direct evidence that giant sperm have been a feature of this taxon for at least 16 Myr and provide an additional criterion (i.e. longevity) to test hypotheses relating to origin and function of giant sperm in the animal kingdom. We further argue that the highly resistant, most probably chitinous coats of giant ostracod sperm may play a role in delaying decay processes, favouring early mineralization of soft tissue. PMID:24827442
Epidemiology, genetic, natural history and clinical presentation of giant cerebral aneurysms.
Lonjon, M; Pennes, F; Sedat, J; Bataille, B
2015-12-01
Giant cerebral aneurysms represent 5% of intracranial aneurysms, and become symptomatic between 40 and 70 years with a female predominance. In the paediatric population, the giant aneurysm rate is higher than in the adult population. Classified as saccular, fusiform and serpentine, the natural history of giant cerebral aneurysms is characterized by thrombosis, growth and rupture. The pathogenesis of these giant aneurysms is influenced by a number of risk factors, including genetic variables. Genome-wide association studies have identified some chromosomes highlighting candidate genes. Although these giant aneurysms can occur at the same locations as their smaller counterparts, a predilection for the cavernous location has been observed. Giant aneurysms present with symptoms caused by a mass effect depending on their location or by rupture; ischemic manifestations rarely reveal the aneurysm. If the initial clinical descriptions have been back up by imagery, the clinical context with a pertinent analysis of the risk factors remain the cornerstone for the management decisions of these lesions. Five year cumulative rupture rates for patients with giant aneurysm were 40% for those located on the anterior part of circle of Willis and 50% for those on the posterior part. The poor outcome of untreated patients justifies the therapeutic risks. Copyright © 2015. Published by Elsevier Masson SAS.
DISCOVERY OF SUPER-Li-RICH RED GIANTS IN DWARF SPHEROIDAL GALAXIES
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kirby, Evan N.; Fu, Xiaoting; Deng, Licai
2012-06-10
Stars destroy lithium (Li) in their normal evolution. The convective envelopes of evolved red giants reach temperatures of millions of kelvin, hot enough for the {sup 7}Li(p, {alpha}){sup 4}He reaction to burn Li efficiently. Only about 1% of first-ascent red giants more luminous than the luminosity function bump in the red giant branch exhibit A(Li) > 1.5. Nonetheless, Li-rich red giants do exist. We present 15 Li-rich red giants-14 of which are new discoveries-among a sample of 2054 red giants in Milky Way dwarf satellite galaxies. Our sample more than doubles the number of low-mass, metal-poor ([Fe/H] {approx}< -0.7) Li-richmore » red giants, and it includes the most-metal-poor Li-enhanced star known ([Fe/H] = -2.82, A(Li){sub NLTE} = 3.15). Because most of the stars have Li abundances larger than the universe's primordial value, the Li in these stars must have been created rather than saved from destruction. These Li-rich stars appear like other stars in the same galaxies in every measurable regard other than Li abundance. We consider the possibility that Li enrichment is a universal phase of evolution that affects all stars, and it seems rare only because it is brief.« less
Wang, Tao; Chen, Zuqin; Xie, Yue; Hou, Rong; Wu, Qidun; Gu, Xiaobing; Lai, Weiming; Peng, Xuerong; Yang, Guangyou
2015-06-25
Cryptosporidium spp. have been extensively reported to cause significant diarrheal disease in humans and domestic animals. On the contrary, little information is available on the prevalence and characterization of Cryptosporidium in wild animals in China, especially in giant pandas. The aim of the present study was to detect Cryptosporidium infections and identify Cryptosporidium species at the molecular level in both captive and wild giant pandas in Sichuan province, China. Using a PCR approach, we amplified and sequenced the 18S rRNA gene from 322 giant pandas fecal samples (122 from 122 captive individuals and 200 collected from four habitats) in Sichuan province, China. The Cryptosporidium species/genotypes were identified via a BLAST comparison against published Cryptosporidium sequences available in GenBank followed by phylogenetic analysis. The results revealed that both captive and wild giant pandas were infected with a single Cryptosporidium species, C. andersoni, at a prevalence of 15.6% (19/122) and 0.5% (1/200) in captive and wild giant pandas, respectively. The present study revealed the existence of C. andersoni in both captive and wild giant panda fecal samples for the first time, and also provided useful fundamental data for further research on the molecular epidemiology and control of Cryptosporidium infection in giant pandas.
Exotic Earths: forming habitable worlds with giant planet migration.
Raymond, Sean N; Mandell, Avi M; Sigurdsson, Steinn
2006-09-08
Close-in giant planets (e.g., "hot Jupiters") are thought to form far from their host stars and migrate inward, through the terrestrial planet zone, via torques with a massive gaseous disk. Here we simulate terrestrial planet growth during and after giant planet migration. Several-Earth-mass planets also form interior to the migrating jovian planet, analogous to recently discovered "hot Earths." Very-water-rich, Earth-mass planets form from surviving material outside the giant planet's orbit, often in the habitable zone and with low orbital eccentricities. More than a third of the known systems of giant planets may harbor Earth-like planets.
Identifying Li-rich giants from low-resolution spectroscopic survey
NASA Astrophysics Data System (ADS)
Kumar, Yerra Bharat; Reddy, Bacham Eswar; Zhao, Gang
2018-04-01
In this paper we discuss our choice of a large unbiased sample used for the survey of red giant branch stars for finding Li-rich K giants, and the method used for identifying Li-rich candidates using low-resolution spectra. The sample has 2000 giants within a mass range of 0.8 to 3.0it{M}_{⊙}. Sample stars were selected from the Hipparcos catalogue with colour (B-V) and luminosity (it{L}/it{L}_{⊙}) in such way that the sample covers RGB evolution from its base towards RGB tip passing through first dredge-up and luminosity bump. Low-resolution (R ≈ 2000, 3500, 5000) spectra were obtained for all sample stars. Using core strength ratios of lines at Li I 6707 Å and its adjacent line Ca I 6717 Å we successfully identified 15 K giants with A(Li) > 1.5 dex, which are defined as Li-rich K giants. The results demonstrate the usefulness of low-resolution spectra to measure Li abundance and identify Li-rich giants from a large sample of stars in relatively shorter time periods.
[Clinicopathologic characteristics of hemangiopericytoma/solitary fibrous tumor with giant cells].
Wang, Hai-yan; Fan, Qin-he; Gong, Qi-xing; Wang, Zheng
2009-03-01
To study the pathological characteristics, diagnosis and differential diagnoses of hemangiopericytoma-solitary fibrous tumor with giant cells. Pathological characteristics of seven cases of orbital and extraorbital hemangiopericytoma-solitary fibrous tumors with giant cells were evaluated by HE and immunohistochemistry (EnVision method). Two cases were located in the orbit, one of which had recurred. Five cases were located in the extraorbital regions. Histologically, the tumors were well-circumscribed and composed of non-atypical, round to spindle cells with collagen deposition in the stroma. The tumors had prominent vasculatures and in areas, pseudovascular spaces lined by multinucleated giant cells lining which were also present in the stroma. Immunohistochemically, both neoplastic cells and multinucleate giant cells expressed CD34. Seven patients underwent tumor excision and were well and without tumor recurrence upon the clinical follow-up. Hemangiopericytoma-solitary fibrous tumor with giant cells is an intermediate soft tissue tumor. It typically involves the orbital or extraorbital regions. Histologically, the tumor should be distinguished from giant cell fibroblastoma, pleomorphic hyalinzing angiectatic tumor of soft part and angiomatoid fibrous histiocytoma.
NASA Technical Reports Server (NTRS)
Buss, Richard H., Jr.; Tielens, A. G. G. M.; Snow, Theodore P.
1991-01-01
The mid-infrared spectra of carbon giant stars with hot companions are investigated in order to search for infrared emission bands from polycyclic aromatic hydrocarbons (PAH) in the envelopes of the C giants. A strong 8-micron emission band found in TU Tau = HD 38218 is attributed to the binary A star companion. It is argued that if the 8-micron feature in HD 38218 arises from PAHs, they seem to be important constituents of the C-giant shell, and they might be large compared with some interstellar PAHs. It is suggested that because no other IR spectra of C giants show clear PAH features, the greater flux of hard radiation in the binary HD 38218 seems likely to be responsible for the 8-micron feature and for its absence in many other C giants. Thus, PAHs could be present in the same amounts relative to SiC grains in the shells of similar single C giants, and the formation of carbonaceous grains could proceed through the formation of PAHs in C giant shells.
Kuiper Prize: Giant Planet Atmospheres
NASA Astrophysics Data System (ADS)
Ingersoll, Andrew P.
2007-10-01
The study of giant planet atmospheres is near and dear to me, for several reasons. First, the giant planets are photogenic; the colored clouds are great tracers, and one can make fantastic movies of the atmosphere in motion. Second, the giant planets challenge us with storms that last for hundreds of years and winds that blow faster the farther you go from the sun. Third, they remind us of Earth with their hurricanes, auroras, and lightning, but they also are the link to the 200 giant planets that have been discovered around other stars. This talk will cover the past, present, and future (one hopes) of giant planet research. I will review the surprises of the Voyager and Galileo eras, and will discuss what we are learning now from the Cassini orbiter. I will review the prospects for answering the outstanding questions like: Where's the water? What is providing the colors of the clouds? How deep do the features extend? Where do the winds get their energy? What is the role of the magnetic field? Finally, I will briefly discuss how extrasolar giant planets compare with objects in our own solar system.
GIANT 2.0: genome-scale integrated analysis of gene networks in tissues.
Wong, Aaron K; Krishnan, Arjun; Troyanskaya, Olga G
2018-05-25
GIANT2 (Genome-wide Integrated Analysis of gene Networks in Tissues) is an interactive web server that enables biomedical researchers to analyze their proteins and pathways of interest and generate hypotheses in the context of genome-scale functional maps of human tissues. The precise actions of genes are frequently dependent on their tissue context, yet direct assay of tissue-specific protein function and interactions remains infeasible in many normal human tissues and cell-types. With GIANT2, researchers can explore predicted tissue-specific functional roles of genes and reveal changes in those roles across tissues, all through interactive multi-network visualizations and analyses. Additionally, the NetWAS approach available through the server uses tissue-specific/cell-type networks predicted by GIANT2 to re-prioritize statistical associations from GWAS studies and identify disease-associated genes. GIANT2 predicts tissue-specific interactions by integrating diverse functional genomics data from now over 61 400 experiments for 283 diverse tissues and cell-types. GIANT2 does not require any registration or installation and is freely available for use at http://giant-v2.princeton.edu.
Carbon and nitrogen abundances in red giant stars in the globular cluster 47 Tucanae
NASA Technical Reports Server (NTRS)
Dickens, R. J.; Bell, R. A.; Gustafsson, B.
1979-01-01
The effects of changes in temperature, gravity, overall metal abundance, and carbon and nitrogen abundances have been investigated for model stellar spectra and colors representing globular-cluster giants of moderate metal deficiency. The results are presented in the form of spectral atlases and theoretical color-color diagrams. Using these results, approximate abundances of carbon and nitrogen have been derived for some red giant stars in 47 Tuc, from intermediate- and low-dispersion spectra and from intermediate- and narrow-band photometry. In all the normal giants studied, nitrogen is overabundant by up to about a factor of 5 (the precise value depends on the adopted carbon abundance), with different enhancements for different giants. The observational material is not sufficient to distinguish between a normal carbon abundance and a slight carbon depletion for the giant-branch stars, but carbon appears to be somewhat depleted in stars on the asymptotic giant branch. A most probable value of M/H = -0.8 for the overall cluster metal abundance is suggested from analysis of Stromgren photometry of red horizontal-branch stars.
The expression of ADAM12 (meltrin alpha) in human giant cell tumours of bone.
Tian, B L; Wen, J M; Zhang, M; Xie, D; Xu, R B; Luo, C J
2002-12-01
To examine the expression of ADAM12 (meltrin alpha), a member of the disintegrin and metalloprotease (ADAM) family, in human giant cell tumours of the bone, skeletal muscle tissue from human embryos, and human adult skeletal muscle tissue. ADAM12 mRNA was detected by reverse transcription polymerase chain reaction and in situ hybridisation. ADAM12 mRNA was detected in 14 of the 20 giant cell tumours of bone and in three of the six tumour cell cultures. The expression of ADAM12 in cells cultured from the tumour was linked to the presence of multinucleated giant cells. ADAM12 mRNA could not be detected in the five adult skeletal muscle tissue samples, although it was found in the two embryonic skeletal muscle tissue samples. ADAM12 mRNA was localised to the cytoplasm of multinucleated giant cells and some mononuclear stromal cells. These results indicate that multinucleated giant cells are formed by the cell fusion of mononuclear stromal cells in giant cell tumours of bone and that ADAM12 is involved in the cell fusion process.
Mimivirus: leading the way in the discovery of giant viruses of amoebae.
Colson, Philippe; La Scola, Bernard; Levasseur, Anthony; Caetano-Anollés, Gustavo; Raoult, Didier
2017-04-01
The accidental discovery of the giant virus of amoeba - Acanthamoeba polyphaga mimivirus (APMV; more commonly known as mimivirus) - in 2003 changed the field of virology. Viruses were previously defined by their submicroscopic size, which probably prevented the search for giant viruses, which are visible by light microscopy. Extended studies of giant viruses of amoebae revealed that they have genetic, proteomic and structural complexities that were not thought to exist among viruses and that are comparable to those of bacteria, archaea and small eukaryotes. The giant virus particles contain mRNA and more than 100 proteins, they have gene repertoires that are broader than those of other viruses and, notably, some encode translation components. The infection cycles of giant viruses of amoebae involve virus entry by amoebal phagocytosis and replication in viral factories. In addition, mimiviruses are infected by virophages, defend against them through the mimivirus virophage resistance element (MIMIVIRE) system and have a unique mobilome. Overall, giant viruses of amoebae, including mimiviruses, marseilleviruses, pandoraviruses, pithoviruses, faustoviruses and molliviruses, challenge the definition and classification of viruses, and have increasingly been detected in humans.
Three cases giant panda attack on human at Beijing Zoo
Zhang, Peixun; Wang, Tianbing; Xiong, Jian; Xue, Feng; Xu, Hailin; Chen, Jianhai; Zhang, Dianying; Fu, Zhongguo; Jiang, Baoguo
2014-01-01
Panda is regarded as Chinese national treasure. Most people always thought they were cute and just ate bamboo and had never imagined a panda could be vicious. Giant panda attacks on human are rare. There, we present three cases of giant panda attacks on humans at the Panda House at Beijing Zoo from September 2006 to June 2009 to warn people of the giant panda’s potentially dangerous behavior. PMID:25550978
NASA Astrophysics Data System (ADS)
Rawls, Meredith L.; Gaulme, Patrick; McKeever, Jean; Jackiewicz, Jason
2016-01-01
Thanks to advances in asteroseismology, red giants have become astrophysical laboratories for studying stellar evolution and probing the Milky Way. However, not all red giants show solar-like oscillations. It has been proposed that stronger tidal interactions from short-period binaries and increased magnetic activity on spotty giants are linked to absent or damped solar-like oscillations, yet each star tells a nuanced story. In this work, we characterize a subset of red giants in eclipsing binaries observed by Kepler. The binaries exhibit a range of orbital periods, solar-like oscillation behavior, and stellar activity. We use orbital solutions together with a suite of modeling tools to combine photometry and spectroscopy in a detailed analysis of tidal synchronization timescales, star spot activity, and stellar evolution histories. These red giants offer an unprecedented opportunity to test stellar physics and are important benchmarks for ensemble asteroseismology.
Giant pandas can discriminate the emotions of human facial pictures.
Li, Youxu; Dai, Qiang; Hou, Rong; Zhang, Zhihe; Chen, Peng; Xue, Rui; Feng, Feifei; Chen, Chao; Liu, Jiabin; Gu, Xiaodong; Zhang, Zejun; Qi, Dunwu
2017-08-16
Previous studies have shown that giant pandas (Ailuropoda melanoleuca) can discriminate face-like shapes, but little is known about their cognitive ability with respect to the emotional expressions of humans. We tested whether adult giant pandas can discriminate expressions from pictures of half of a face and found that pandas can learn to discriminate between angry and happy expressions based on global information from the whole face. Young adult pandas (5-7 years old) learned to discriminate expressions more quickly than older individuals (8-16 years old), but no significant differences were found between females and males. These results suggest that young adult giant pandas are better at discriminating emotional expressions of humans. We showed for the first time that the giant panda, can discriminate the facial expressions of humans. Our results can also be valuable for the daily care and management of captive giant pandas.
Mechanical model of giant photoexpansion in a chalcogenide glass and the role of photofluidity
NASA Astrophysics Data System (ADS)
Buisson, Manuel; Gueguen, Yann; Laniel, Romain; Cantoni, Christopher; Houizot, Patrick; Bureau, Bruno; Sangleboeuf, Jean-Christophe; Lucas, Pierre
2017-07-01
An analytical model is developed to describe the phenomenon of giant photoexpansion in chalcogenide glasses. The proposed micro-mechanical model is based on the description of photoexpansion as a new type of eigenstrain, i.e. a deformation analogous to thermal expansion induced without external forces. In this framework, it is the viscoelastic flow induced by photofluidity which enable the conversion of the self-equilibrated stress into giant photoexpansion. This simple approach yields good fits to experimental data and demonstrates, for the first time, that the photoinduced viscous flow actually enhances the giant photoexpansion or the giant photocontraction as it has been suggested in the literature. Moreover, it highlights that the shear relaxation time due to photofluidity controls the expansion kinetic. This model is the first step towards describing giant photoexpansion from the point of view of mechanics and it provides the framework for investigating this phenomenon via numerical simulations.
Metastatic giant basal cell carcinoma: a case report.
Bellahammou, Khadija; Lakhdissi, Asmaa; Akkar, Othman; Rais, Fadoua; Naoual, Benhmidou; Elghissassi, Ibrahim; M'rabti, Hind; Errihani, Hassan
2016-01-01
Basal cell carcinoma is the most common skin cancer, characterised by a slow growing behavior, metastasis are extremely rare, and it occurs in less than 0, 1% of all cases. Giant basal cell carcinoma is a rare form of basal cell carcinoma, more aggressive and defined as a tumor measuring more than 5 cm at its largest diameter. Only 1% of all basal cell carcinoma develops to a giant basal cell carcinoma, resulting of patient's negligence. Giant basal cell carcinoma is associated with higher potential of metastasis and even death, compared to ordinary basal cell carcinoma. We report a case of giant basal cell carcinoma metastaticin lung occurring in a 79 years old male patient, with a fatal evolution after one course of systemic chemotherapy. Giant basal cell carcinoma is a very rare entity, early detection of these tumors could prevent metastasis occurrence and improve the prognosis of this malignancy.
Imaging Active Giants and Comparisons to Doppler Imaging
NASA Astrophysics Data System (ADS)
Roettenbacher, Rachael
2018-04-01
In the outer layers of cool, giant stars, stellar magnetism stifles convection creating localized starspots, analogous to sunspots. Because they frequently cover much larger regions of the stellar surface than sunspots, starspots of giant stars have been imaged using a variety of techniques to understand, for example, stellar magnetism, differential rotation, and spot evolution. Active giants have been imaged using photometric, spectroscopic, and, only recently, interferometric observations. Interferometry has provided a way to unambiguously see stellar surfaces without the degeneracies experienced by other methods. The only facility presently capable of obtaining the sub-milliarcsecond resolution necessary to not only resolve some giant stars, but also features on their surfaces is the Center for High-Angular Resolution Astronomy (CHARA) Array. Here, an overview will be given of the results of imaging active giants and details on the recent comparisons of simultaneous interferometric and Doppler images.
Acromegalic gigantism, physicians and body snatching. Past or present?
de Herder, Wouter W
2012-09-01
The skeletons of 2 famous acromegalic giants: Charles Byrne (1761-1783) and Henri Cot = Joseph Dusorc (1883-1912) and the embalmed body of the famous acromegalic giant Édouard Beaupré (1881-1904) all ended up in the medical collections of museums despite the fact that these patients had never donated or even refused to donate their corpses, nor had their relatives given permission. The corpse of the acromegalic giant John Aasen (1890-1938) was voluntarily donated to a physician annex collector of trivia from acromegalic giants. The autopsy on the acromegalic giant John Turner (1874-1911) was performed during his funeral ceremony without the relatives being informed. Only recently, the acromegalic giant Alexander Sizonenko (1959-2012) was made a financial offer during his life in exchange for his body after his death. The case-histories of these 6 patients and also the circumstances that led to the (in-) voluntary donation of their bodies are reviewed.
Timing of the formation and migration of giant planets as constrained by CB chondrites
Johnson, Brandon C.; Walsh, Kevin J.; Minton, David A.; Krot, Alexander N.; Levison, Harold F.
2016-01-01
The presence, formation, and migration of giant planets fundamentally shape planetary systems. However, the timing of the formation and migration of giant planets in our solar system remains largely unconstrained. Simulating planetary accretion, we find that giant planet migration produces a relatively short-lived spike in impact velocities lasting ~0.5 My. These high-impact velocities are required to vaporize a significant fraction of Fe,Ni metal and silicates and produce the CB (Bencubbin-like) metal-rich carbonaceous chondrites, a unique class of meteorites that were created in an impact vapor-melt plume ~5 My after the first solar system solids. This indicates that the region where the CB chondrites formed was dynamically excited at this early time by the direct interference of the giant planets. Furthermore, this suggests that the formation of the giant planet cores was protracted and the solar nebula persisted until ~5 My. PMID:27957541
Timing of the formation and migration of giant planets as constrained by CB chondrites.
Johnson, Brandon C; Walsh, Kevin J; Minton, David A; Krot, Alexander N; Levison, Harold F
2016-12-01
The presence, formation, and migration of giant planets fundamentally shape planetary systems. However, the timing of the formation and migration of giant planets in our solar system remains largely unconstrained. Simulating planetary accretion, we find that giant planet migration produces a relatively short-lived spike in impact velocities lasting ~0.5 My. These high-impact velocities are required to vaporize a significant fraction of Fe,Ni metal and silicates and produce the CB (Bencubbin-like) metal-rich carbonaceous chondrites, a unique class of meteorites that were created in an impact vapor-melt plume ~5 My after the first solar system solids. This indicates that the region where the CB chondrites formed was dynamically excited at this early time by the direct interference of the giant planets. Furthermore, this suggests that the formation of the giant planet cores was protracted and the solar nebula persisted until ~5 My.
The comparative effect of FUV, EUV and X-ray disc photoevaporation on gas giant separations
NASA Astrophysics Data System (ADS)
Jennings, Jeff; Ercolano, Barbara; Rosotti, Giovanni P.
2018-04-01
Gas giants' early (≲ 5 Myr) orbital evolution occurs in a disc losing mass in part to photoevaporation driven by high energy irradiance from the host star. This process may ultimately overcome viscous accretion to disperse the disc and halt migrating giants by starving their orbits of gas, imprinting on giant planet separations in evolved systems. Inversion of this distribution could then give insight into whether stellar FUV, EUV or X-ray flux dominates photoevaporation, constraining planet formation and disc evolution models. We use a 1D hydrodynamic code in population syntheses for gas giants undergoing Type II migration in a viscously evolving disc subject to either a primarily FUV, EUV or X-ray flux from a pre-solar T Tauri star. The photoevaporative mass loss profile's unique peak location and width in each energetic regime produces characteristic features in the distribution of giant separations: a severe dearth of ≲ 2 MJ planets interior to 5 AU in the FUV scenario, a sharp concentration of ≲ 3 MJ planets between ≈1.5 - 2 AU in the EUV case, and a relative abundance of ≈2 - 3.5 MJ giants interior to 0.5 AU in the X-ray model. These features do not resemble the observational sample of gas giants with mass constraints, though our results do show some weaker qualitative similarities. We thus assess how the differing photoevaporative profiles interact with migrating giants and address the effects of large model uncertainties as a step to better connect disc models with trends in the exoplanet population.
The comparative effect of FUV, EUV and X-ray disc photoevaporation on gas giant separations
NASA Astrophysics Data System (ADS)
Jennings, Jeff; Ercolano, Barbara; Rosotti, Giovanni P.
2018-07-01
Gas giants' early (≲5 Myr) orbital evolution occurs in a disc losing mass in part to photoevaporation driven by high energy irradiance from the host star. This process may ultimately overcome viscous accretion to disperse the disc and halt migrating giants by starving their orbits of gas, imprinting on giant planet separations in evolved systems. Inversion of this distribution could then give insight into whether the stellar FUV, EUV or X-ray flux dominates photoevaporation, constraining planet formation and disc evolution models. We use a 1D hydrodynamic code in population syntheses for gas giants undergoing Type II migration in a viscously evolving disc subject to either a primarily FUV, EUV or X-ray flux from a pre-solar T Tauri star. The photoevaporative mass loss profile's unique peak location and width in each energetic regime produces characteristic features in the distribution of giant separations: a severe dearth of ≲2 MJ planets interior to 5 au in the FUV scenario, a sharp concentration of ≲3 MJ planets between ≈1.5-2 au in the EUV case and a relative abundance of ≈2-3.5 MJ giants interior to 0.5 au in the X-ray model. These features do not resemble the observational sample of gas giants with mass constraints, although our results do show some weaker qualitative similarities. We thus assess how the differing photoevaporative profiles interact with migrating giants and address the effects of large model uncertainties as a step to better connect disc models with trends in the exoplanet population.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Genda, H.; Kobayashi, H.; Kokubo, E., E-mail: genda@elsi.jp
In our solar system, Mars-sized protoplanets frequently collided with each other during the last stage of terrestrial planet formation, called the giant impact stage. Giant impacts eject a large amount of material from the colliding protoplanets into the terrestrial planet region, which may form debris disks with observable infrared excesses. Indeed, tens of warm debris disks around young solar-type stars have been observed. Here we quantitatively estimate the total mass of ejected materials during the giant impact stages. We found that ∼0.4 times the Earth’s mass is ejected in total throughout the giant impact stage. Ejected materials are ground down bymore » collisional cascade until micron-sized grains are blown out by radiation pressure. The depletion timescale of these ejected materials is determined primarily by the mass of the largest body among them. We conducted high-resolution simulations of giant impacts to accurately obtain the mass of the largest ejected body. We then calculated the evolution of the debris disks produced by a series of giant impacts and depleted by collisional cascades to obtain the infrared excess evolution of the debris disks. We found that the infrared excess is almost always higher than the stellar infrared flux throughout the giant impact stage (∼100 Myr) and is sometimes ∼10 times higher immediately after a giant impact. Therefore, giant impact stages would explain the infrared excess from most observed warm debris disks. The observed fraction of stars with warm debris disks indicates that the formation probability of our solar-system-like terrestrial planets is approximately 10%.« less
Spectral calibration in the mid-infrared: Challenges and solutions
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sloan, G. C.; Herter, T. L.; Houck, J. R.
2015-01-01
We present spectra obtained with the Infrared Spectrograph on the Spitzer Space Telescope of 33 K giants and 20 A dwarfs to assess their suitability as spectrophotometric standard stars. The K giants confirm previous findings that the strength of the SiO absorption band at 8 μm increases for both later optical spectral classes and redder (B–V){sub 0} colors, but with considerable scatter. For K giants, the synthetic spectra underpredict the strengths of the molecular bands from SiO and OH. For these reasons, the assumed true spectra for K giants should be based on the assumption that molecular band strengths inmore » the infrared can be predicted accurately from neither optical spectral class or color nor synthetric spectra. The OH bands in K giants grow stronger with cooler stellar temperatures, and they are stronger than predicted by synthetic spectra. As a group, A dwarfs are better behaved and more predictable than the K giants, but they are more likely to show red excesses from debris disks. No suitable A dwarfs were located in parts of the sky continuously observable from Spitzer, and with previous means of estimating the true spectra of K giants ruled out, it was necessary to use models of A dwarfs to calibrate spectra of K giants from observed spectral ratios of the two groups and then use the calibrated K giants as standards for the full database of infrared spectra from Spitzer. We also describe a lingering artifact that affects the spectra of faint blue sources at 24 μm.« less
Comparative morphology of the muscles of mastication in the giant panda and the Asiatic black bear.
Endo, Hideki; Taru, Hajime; Yamamoto, Masako; Arishima, Kazuyoshi; Sasaki, Motoki
2003-06-01
The morphological differences in the muscles of mastication between the giant panda (Ailuropoda melanoleuca) and the Asiatic black bear (Ursus thibetanus) were sought to confirm the adaptational strategy of these muscles in the giant panda. We measured some skull characteristics and weighed the muscles of mastication, and macroscopically observed the muscles of mastication in the two species. The noticeable differences between the two species are classified as follows: (1) The size ratio of the zygomatic width was much larger in the giant panda than in the Asiatic black bear. (2) The weight ratio of the two pterygoid muscles was also much larger in the giant panda than in the Asiatic black bear. (3) The lateral slips of the temporal muscles are thicker and stronger in the Asiatic black bear than in the giant panda. (4) The deep layer of the masseter muscle was rostrocaudally divided, and a complicated running of tendons is observed in the giant panda. (5) The two pterygoid muscles were much larger and well-developed in the giant panda than in the Asiatic black bear. The points (1) and (4) may be related to the generation of the force necessary to chew the bamboo in the giant panda. We thought that the large mass of the masseter and temporal muscles are needed in this species. In the points of (2) and (5), the two pterygoid muscles were obviously different in form and weight ratio between the two species. We suggest that the two pterygoid muscles may act as an additional force generator to dorsoventrally press and crush bamboo stems.
Direct imaging search for the "missing link" in giant planet formation
NASA Astrophysics Data System (ADS)
Ngo, Henry; Mawet, Dimitri; Ruane, Garreth; Xuan, Wenhao; Bowler, Brendan; Cook, Therese; Zawol, Zoe
2018-01-01
While transit and radial velocity detection techniques have probed giant planet populations at close separations (within a few au), current direct imaging surveys are finding giant planets at separations of 10s-100s au. Furthermore, these directly imaged planets are very massive, including some with masses above the deuterium burning limit. It is not certain whether these objects represent the high mass end of planet formation scenarios or the low mass end of star formation. We present a direct imaging survey to search for the "missing link" population between the close-in RV and transiting giant planets and the extremely distant directly imaged giant planets (i.e. giant planets between 5-10 au). Finding and characterizing this population allows for comparisons with the formation models of closer-in planets and connects directly imaged planets with closer-in planets in semi-major axis phase space. In addition, microlensing surveys have suggested a large reservoir of giant planets exist in this region. To find these "missing link" giant planets, our survey searches for giant planets around M-stars. The ubiquity of M-stars provide a large number of nearby targets and their L-band contrast with planets allow for sensitivities to smaller planet masses than surveys conducted at shorter wavelengths. Along with careful target selection, we use Keck's L-band vector vortex coronagraph to enable sensitivities of a few Jupiter masses as close as 4 au to their host stars. We present our completed 2-year survey targeting 200 young (10-150 Myr), nearby M-stars and our ongoing work to follow-up over 40 candidate objects.
Giant aerosol observations with cloud radar: methodology and effects
NASA Astrophysics Data System (ADS)
Guma Claramunt, Pilar; Madonna, Fabio; Amodeo, Aldo; Bauer-Pfundstein, Matthias; Papagiannopoulos, Nikolaos; Pappalardo, Gelsomina
2017-04-01
Giant aerosol particles can act as Giant Cloud Condensation Nuclei (GCCN), and determine the droplet concentration at the cloud formation, the clouds albedo and lifetime, and the precipitation formation. In addition, depending on their composition, they can also act as IN. It is not yet clear if they can also expedite rain processes. The main techniques used nowadays in measuring aerosols, which are lidar and sun photometer, cannot retrieve aerosol microphysical properties for particles bigger than a few microns, which means that they do not account for giant aerosols. Therefore, the distribution and impact in the atmosphere and climate of these particles is not well known and the aerosol transport models largely underestimate them. Recent studies have demonstrated that cloud radars are able to detect ultragiant volcanic aerosols also at a large distance from the source. In this study, an innovative methodology for the observation of giant aerosols using the millimeter wavelength radar has been developed and applied to 6 years of measurements carried out at CNR-IMAA Atmospheric Observatory (CIAO), in Potenza, South Italy, finding more than 40 giant aerosol events per year and a good agreement with the aerosol climatologic data. Besides, the effects of giant aerosols in the local and regional meteorology have been studied by correlating several atmospheric variables in the time period following the observation of giant particles. The meteorological situation has been assessed through the data classification into cases characterized by different pressure vertical velocities at the upper atmosphere (400 hPa), Giant aerosols are correlated to lower values of the Cloud Optical Depth (COD) in presence of stable or unstable atmospheric conditions while higher values are found for an intermediate stability. The giant aerosols effects on the Liquid Water Path (LWP) are closely linked to those in the Aerosol Optical Thickness (AOD). The highest increases in the LWP occurs together with the increases of AOD. Finally, the effects of giant aerosols on precipitation at a regional scale have been studied. The observation of giant aerosols can be correlated to an enhancement of the accumulated precipitation, which is quite relevant in the first 12 hours after their observation, as well as of the maximum rain rate in presence of the unstable atmospheric conditions. The increase in the maximum rain rate is instead more remarkable in correlation with stable atmospheric conditions and mainly during the first 6 hours after their observations.
Entry Probe Missions to the Giant Planets
NASA Astrophysics Data System (ADS)
Spilker, T. R.; Atkinson, D. H.; Atreya, S. K.; Colaprete, A.; Cuzzi, J. N.; Spilker, L. J.; Coustenis, A.; Venkatapathy, E.; Reh, K.; Frampton, R.
2009-12-01
The primary motivation for in situ probe missions to the outer planets derives from the need to constrain models of solar system formation and the origin and evolution of atmospheres, to provide a basis for comparative studies of the gas and ice giants, and to provide a valuable link to extrasolar planetary systems. As time capsules of the solar system, the gas and ice giants offer a laboratory to better understand the atmospheric chemistries, dynamics, and interiors of all the planets, including Earth; and it is within the atmospheres and interiors of the giant planets that material diagnostic of the epoch of formation can be found, providing clues to the local chemical and physical conditions existing at the time and location at which each planet formed. Measurements of current conditions and processes in those atmospheres inform us about their evolution since formation and into the future, providing information about our solar system’s evolution, and potentially establishing a framework for recognizing extrasolar giant planets in different stages of their evolution. Detailed explorations and comparative studies of the gas and ice giant planets will provide a foundation for understanding the integrated dynamic, physical, and chemical origins, formation, and evolution of the solar system. To allow reliable conclusions from comparative studies of gas giants Jupiter and Saturn, an entry probe mission to Saturn is needed to complement the Galileo Probe measurements at Jupiter. These measurements provide the basis for a significantly better understanding of gas giant formation in the context of solar system formation. A probe mission to either Uranus or Neptune will be needed for comparative studies of the gas giants and the ice giants, adding knowledge of ice giant origins and thus making further inroads in our understanding of solar system formation. Recognizing Jupiter’s spatial variability and the need to understand its implications for global composition, returning to Jupiter with a follow-on probe mission, possibly with technological advances allowing a multiple-probe mission, would make use of data from the Juno mission to guide entry location and measurement suite selection. This poster summarizes a white paper prepared for the Space Studies Board’s 2013-2022 Planetary Science Decadal Survey. It discusses specific measurements to be made by planetary probes at the giant planets, rationales and priorities for those measurements, and locations within the destination atmospheres where the measurements are best made.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ohori, N.P.; Sciurba, F.C.; Owens, G.R.
We report four cases of giant-cell interstitial pneumonia that occurred in association with exposure to hard metals. All patients presented with chronic interstitial lung disease and had open-lung biopsies that revealed marked interstitial fibrosis, cellular interstitial infiltrates, and prominent intraalveolar macrophages as well as giant cells displaying cellular cannibalism. We also review the literature to determine the sensitivity and specificity of giant-cell interstitial pneumonia for hard-metal pneumoconiosis. Although hard-metal pneumoconiosis may take the form of usual interstitial pneumonia, desquamative interstitial pneumonia, and giant-cell interstitial pneumonia, the finding of giant-cell interstitial pneumonia is almost pathognomonic of hard-metal disease and should provokemore » an investigation of occupational exposure. 25 references.« less
Tests of the Giant Impact Hypothesis
NASA Technical Reports Server (NTRS)
Jones, J. H.
1998-01-01
The giant impact hypothesis has gained popularity as a means of explaining a volatile-depleted Moon that still has a chemical affinity to the Earth. As Taylor's Axiom decrees, the best models of lunar origin are testable, but this is difficult with the giant impact model. The energy associated with the impact would be sufficient to totally melt and partially vaporize the Earth. And this means that there should he no geological vestige of Barber times. Accordingly, it is important to devise tests that may be used to evaluate the giant impact hypothesis. Three such tests are discussed here. None of these is supportive of the giant impact model, but neither do they disprove it.
Sarmento, Dmitry José de Santana; Carvalho, Sérgio Henrique Gonçalves de; Araújo, José Cadmo Wanderley Peregrino de; Carvalho, Marianne de Vasconcelos; Silveira, Éricka Janine Dantas da
2017-01-01
We report a 35-year-old mulatto female patient with neurofibromatosis Type 1 who presented with facial asymmetry. The patient had two lesions: florid cemento-osseous dysplasia associated with peripheral giant cell granuloma. She was referred for surgical treatment of the peripheral giant cell granuloma and the florid cemento-osseous dysplasia was treated conservatively by a multidisciplinary team. So far, no changes have been observed in the patient's clinical status. We observed no recurrence of peripheral giant cell granuloma. To the best of our knowledge, the present case is the first report of a patient with neurofibromatosis Type 1 associated with a giant cell lesion and florid cemento-osseous dysplasia.
Sarmento, Dmitry José de Santana; de Carvalho, Sérgio Henrique Gonçalves; de Araújo Filho, José Cadmo Wanderley Peregrino; Carvalho, Marianne de Vasconcelos; da Silveira, Éricka Janine Dantas
2017-01-01
We report a 35-year-old mulatto female patient with neurofibromatosis Type 1 who presented with facial asymmetry. The patient had two lesions: florid cemento-osseous dysplasia associated with peripheral giant cell granuloma. She was referred for surgical treatment of the peripheral giant cell granuloma and the florid cemento-osseous dysplasia was treated conservatively by a multidisciplinary team. So far, no changes have been observed in the patient's clinical status. We observed no recurrence of peripheral giant cell granuloma. To the best of our knowledge, the present case is the first report of a patient with neurofibromatosis Type 1 associated with a giant cell lesion and florid cemento-osseous dysplasia. PMID:28538890
Giant cell phlebitis: a potentially lethal clinical entity.
Kunieda, Takeshige; Murayama, Masanori; Ikeda, Tsuneko; Yamakita, Noriyoshi
2012-08-01
An 83-year-old woman presented to us with a 4-week history of general malaise, subjective fever and lower abdominal pain. Despite the intravenous infusion of antibiotics, her blood results and physical condition worsened, resulting in her sudden death. Autopsy study revealed that the medium-sized veins of the mesentery were infiltrated by eosinophil granulocytes, lymphocytes, macrophages and multinucleated giant cells; however, the arteries were not involved. Microscopically, venous giant cell infiltration was observed in the gastrointestinal tract, bladder, retroperitoneal tissues and myocardium. The final diagnosis was giant cell phlebitis, a rare disease of unknown aetiology. This case demonstrates for the first time that giant cell phlebitis involving extra-abdominal organs, including hearts, can cause serious morbidity.
NASA Astrophysics Data System (ADS)
Kissin, Yevgeni; Thompson, Christopher
2015-07-01
The internal rotation of post-main sequence stars is investigated, in response to the convective pumping of angular momentum toward the stellar core, combined with a tight magnetic coupling between core and envelope. The spin evolution is calculated using model stars of initial mass 1, 1.5, and 5 {M}⊙ , taking into account mass loss on the giant branches. We also include the deposition of orbital angular momentum from a sub-stellar companion, as influenced by tidal drag along with the excitation of orbital eccentricity by a fluctuating gravitational quadrupole moment. A range of angular velocity profiles {{Ω }}(r) is considered in the envelope, extending from solid rotation to constant specific angular momentum. We focus on the backreaction of the Coriolis force, and the threshold for dynamo action in the inner envelope. Quantitative agreement with measurements of core rotation in subgiants and post-He core flash stars by Kepler is obtained with a two-layer angular velocity profile: uniform specific angular momentum where the Coriolis parameter {Co}\\equiv {{Ω }}{τ }{con}≲ 1 (here {τ }{con} is the convective time), and {{Ω }}(r)\\propto {r}-1 where {Co}≳ 1. The inner profile is interpreted in terms of a balance between the Coriolis force and angular pressure gradients driven by radially extended convective plumes. Inward angular momentum pumping reduces the surface rotation of subgiants, and the need for a rejuvenated magnetic wind torque. The co-evolution of internal magnetic fields and rotation is considered in Kissin & Thompson, along with the breaking of the rotational coupling between core and envelope due to heavy mass loss.
Carbon and nitrogen abundances in the giant stars of the globular clusters M3 and M13
DOE Office of Scientific and Technical Information (OSTI.GOV)
Suntzeff, N.B.
Carbon and nitrogen abundances, as well as the strengths of calcium II H and K and the ..delta..v = 0 cyanogen band, have been measured in red giant stars in the globular clusters M3 and M13. The data consist of spectrophotometric scans of low resolution (10 A) of 29 giants in M3 and 35 giants in M13 in the wavelength region 3000--5000 A.
Wylie, G.D.; Casazza, Michael L.; Gregory, C.J.; Halstead, B.J.
2010-01-01
The Giant Gartersnake (Thamnophis gigas) is restricted to wetlands of the Central Valley of California. Because of wetland loss in this region, the Giant Gartersnake is both federally and state listed as threatened. We conducted markrecapture studies of four populations of the Giant Gartersnake in the Sacramento Valley (northern Central Valley), California, to obtain baseline data on abundance and density to assist in recovery planning for this species. We sampled habitats that ranged from natural, unmanaged marsh to constructed managed marshes and habitats associated with rice agriculture. Giant Gartersnake density in a natural wetland (1.90 individuals/ha) was an order of magnitude greater than in a managed wetland subject to active season drying (0.17 individuals/ha). Sex ratios at all sites were not different from 1 1, and females were longer and heavier than males. Females had greater body condition than males, and individuals at the least disturbed sites had significantly greater body condition than individuals at the managed wetland. The few remaining natural wetlands in the Central Valley are important, productive habitat for the Giant Gartersnake, and should be conserved and protected. Wetlands constructed and restored for the Giant Gartersnake should be modeled after the permanent, shallow wetlands representative of historic Giant Gartersnake habitat. ?? 2010 Society for the Study of Amphibians and Reptiles.
Territoriality of Giant Otter Groups in an Area with Seasonal Flooding
Leuchtenberger, Caroline; Magnusson, William E.; Mourão, Guilherme
2015-01-01
Territoriality carries costs and benefits, which are commonly affected by the spatial and temporal abundance and predictability of food, and by intruder pressure. Giant otters (Pteronura brasiliensis) live in groups that defend territories along river channels during the dry season using chemical signals, loud vocalizations and agonistic encounters. However, little is known about the territoriality of giant otters during the rainy season, when groups leave their dry season territories and follow fish dispersing into flooded areas. The objective of this study was to analyze long-term territoriality of giant otter groups in a seasonal environment. The linear extensions of the territories of 10 giant otter groups were determined based on locations of active dens, latrines and scent marks in each season. Some groups overlapped the limits of neighboring territories. The total territory extent of giant otters was correlated with group size in both seasons. The extent of exclusive territories of giant otter groups was negatively related to the number of adults present in adjacent groups. Territory fidelity ranged from 0 to 100% between seasons. Some groups maintained their territory for long periods, which demanded constant effort in marking and re-establishing their territories during the wet season. These results indicate that the defense capacity of groups had an important role in the maintenance of giant otter territories across seasons, which may also affect the reproductive success of alpha pairs. PMID:25955248
Provirophages and transpovirons as the diverse mobilome of giant viruses.
Desnues, Christelle; La Scola, Bernard; Yutin, Natalya; Fournous, Ghislain; Robert, Catherine; Azza, Saïd; Jardot, Priscilla; Monteil, Sonia; Campocasso, Angélique; Koonin, Eugene V; Raoult, Didier
2012-10-30
A distinct class of infectious agents, the virophages that infect giant viruses of the Mimiviridae family, has been recently described. Here we report the simultaneous discovery of a giant virus of Acanthamoeba polyphaga (Lentille virus) that contains an integrated genome of a virophage (Sputnik 2), and a member of a previously unknown class of mobile genetic elements, the transpovirons. The transpovirons are linear DNA elements of ~7 kb that encompass six to eight protein-coding genes, two of which are homologous to virophage genes. Fluorescence in situ hybridization showed that the free form of the transpoviron replicates within the giant virus factory and accumulates in high copy numbers inside giant virus particles, Sputnik 2 particles, and amoeba cytoplasm. Analysis of deep-sequencing data showed that the virophage and the transpoviron can integrate in nearly any place in the chromosome of the giant virus host and that, although less frequently, the transpoviron can also be linked to the virophage chromosome. In addition, integrated fragments of transpoviron DNA were detected in several giant virus and Sputnik genomes. Analysis of 19 Mimivirus strains revealed three distinct transpovirons associated with three subgroups of Mimiviruses. The virophage, the transpoviron, and the previously identified self-splicing introns and inteins constitute the complex, interconnected mobilome of the giant viruses and are likely to substantially contribute to interviral gene transfer.
Provirophages and transpovirons as the diverse mobilome of giant viruses
Desnues, Christelle; La Scola, Bernard; Yutin, Natalya; Fournous, Ghislain; Robert, Catherine; Azza, Saïd; Jardot, Priscilla; Monteil, Sonia; Campocasso, Angélique; Koonin, Eugene V.; Raoult, Didier
2012-01-01
A distinct class of infectious agents, the virophages that infect giant viruses of the Mimiviridae family, has been recently described. Here we report the simultaneous discovery of a giant virus of Acanthamoeba polyphaga (Lentille virus) that contains an integrated genome of a virophage (Sputnik 2), and a member of a previously unknown class of mobile genetic elements, the transpovirons. The transpovirons are linear DNA elements of ∼7 kb that encompass six to eight protein-coding genes, two of which are homologous to virophage genes. Fluorescence in situ hybridization showed that the free form of the transpoviron replicates within the giant virus factory and accumulates in high copy numbers inside giant virus particles, Sputnik 2 particles, and amoeba cytoplasm. Analysis of deep-sequencing data showed that the virophage and the transpoviron can integrate in nearly any place in the chromosome of the giant virus host and that, although less frequently, the transpoviron can also be linked to the virophage chromosome. In addition, integrated fragments of transpoviron DNA were detected in several giant virus and Sputnik genomes. Analysis of 19 Mimivirus strains revealed three distinct transpovirons associated with three subgroups of Mimiviruses. The virophage, the transpoviron, and the previously identified self-splicing introns and inteins constitute the complex, interconnected mobilome of the giant viruses and are likely to substantially contribute to interviral gene transfer. PMID:23071316
2000-11-07
The International Space Station ground operations officially turn over the P6 Integrated Truss Structure to the NASA shuttle integration team in a ceremony in the Space Station Processing Facility. A symbolic key is presented to Brent Jett (at left), commander on mission STS-97, which is taking the P6 to the International Space Station. Next to him are (left to right) Bill Dowdell, mission manager; Mark Sorensen, outboard truss cargo element manager for Boeing; and John Elbon, Boeing ISS director of ground operations at KSC. Among the attendees at left watching the ceremony are other STS-97 crew members (in uniform, from left) Mission Specialists Joe Tanner and Carlos Noriega and Pilot Mike Bloomfield. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission involves two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at 10:05 p.m. EST
2000-11-07
The International Space Station ground operations officially turn over the P6 Integrated Truss Structure to the NASA shuttle integration team in a ceremony in the Space Station Processing Facility. A symbolic key is presented to Brent Jett (at left), commander on mission STS-97, which is taking the P6 to the International Space Station. Next to him are (left to right) Bill Dowdell, mission manager; Mark Sorensen, outboard truss cargo element manager for Boeing; and John Elbon, Boeing ISS director of ground operations at KSC. Among the attendees at left watching the ceremony are other STS-97 crew members (in uniform, from left) Mission Specialists Joe Tanner and Carlos Noriega and Pilot Mike Bloomfield. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission involves two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at 10:05 p.m. EST
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gaulme, P.; McKeever, J.; Rawls, M. L.
2013-04-10
Red giant stars are proving to be an incredible source of information for testing models of stellar evolution, as asteroseismology has opened up a window into their interiors. Such insights are a direct result of the unprecedented data from space missions CoRoT and Kepler as well as recent theoretical advances. Eclipsing binaries are also fundamental astrophysical objects, and when coupled with asteroseismology, binaries provide two independent methods to obtain masses and radii and exciting opportunities to develop highly constrained stellar models. The possibility of discovering pulsating red giants in eclipsing binary systems is therefore an important goal that could potentiallymore » offer very robust characterization of these systems. Until recently, only one case has been discovered with Kepler. We cross-correlate the detected red giant and eclipsing-binary catalogs from Kepler data to find possible candidate systems. Light-curve modeling and mean properties measured from asteroseismology are combined to yield specific measurements of periods, masses, radii, temperatures, eclipse timing variations, core rotation rates, and red giant evolutionary state. After using three different techniques to eliminate false positives, out of the 70 systems common to the red giant and eclipsing-binary catalogs we find 13 strong candidates (12 previously unknown) to be eclipsing binaries, one to be a non-eclipsing binary with tidally induced oscillations, and 10 more to be hierarchical triple systems, all of which include a pulsating red giant. The systems span a range of orbital eccentricities, periods, and spectral types F, G, K, and M for the companion of the red giant. One case even suggests an eclipsing binary composed of two red giant stars and another of a red giant with a {delta}-Scuti star. The discovery of multiple pulsating red giants in eclipsing binaries provides an exciting test bed for precise astrophysical modeling, and follow-up spectroscopic observations of many of the candidate systems are encouraged. The resulting highly constrained stellar parameters will allow, for example, the exploration of how binary tidal interactions affect pulsations when compared to the single-star case.« less
Mihlon, Frank; Agrawal, Abishek; Nimjee, Shahid M; Ferrell, Andrew; Zomorodi, Ali R; Smith, Tony P; Britz, Gavin W
2015-01-01
Therapeutic embolization of the common carotid artery (CCA), internal carotid artery (ICA), and vertebral artery (VA) is necessary in the treatment of a subset of chronic arteriovenous fistulas (AVFs), hemorrhages, highly vascularized neoplasms before resection, and giant aneurysms. There are currently no reports of the use of the AMPLATZER Vascular Plug II (AVP II) device to occlude the CCA, ICA, or VA. The objective of this article is to present the Duke Cerebrovascular Center experience using the AVP II device in neurointerventional applications. This case series is a retrospective review of all of the cases at Duke University Hospital in which an AVP II device was used in the CCA, ICA, or VA up to September 2012. The AVP II device was often used in conjunction with embolization coils or as multiple AVP II devices deployed in tandem. During 2010-2012, 8 cases meeting criteria were performed. These included 2 chronic VA to internal jugular AVFs, 1 hemorrhagic CCA to internal jugular AVF secondary to invasive head and neck squamous cell carcinoma, 1 ICA hemorrhage secondary to invasive head and neck squamous cell carcinoma, 1 ICA hemorrhage secondary to trauma, 1 ruptured ICA aneurysm, 1 giant petrous ICA aneurysm, and 1 case of cervical vertebral sarcoma requiring preoperative VA embolization. Successful occlusion of the target vessel was achieved in all 8 cases. There was 1 major complication that consisted of a watershed distribution cerebral infarct; however, this was related to emergent occlusion of the ICA in the setting of intracranial hemorrhage and was not a problem intrinsic to the AVP II device. The AVP II device is relatively large, self-expanding vascular occlusion device that safely allows enhanced, rapid take-down of the CCA, ICA, and VA with low risk of distal migration. Copyright © 2015 Elsevier Inc. All rights reserved.
Surgical management of giant sphenoid wing meningiomas encasing major cerebral arteries.
Champagne, Pierre-Olivier; Lemoine, Emile; Bojanowski, Michel W
2018-04-01
OBJECTIVE Sphenoid wing meningiomas are a heterogeneous group of tumors with variable surgical risks and prognosis. Those that have grown to a very large size, encasing the major cerebral arteries, are associated with a high risk of stroke. In reviewing the authors' series of giant sphenoid wing meningiomas, the goal was to evaluate how the extent of the tumor's invasion of surrounding structures affected the ability to safely remove the tumor and restore function. METHODS The authors conducted a retrospective study of a series of giant sphenoid wing meningiomas operated on between 1996 and 2016. Inclusion criteria were meningiomas with a globoid component ≥ 6 cm, encasing at least 1 major intradural cerebral artery. Extent of resection was measured according to Simpson grade. RESULTS This series included 12 patients, with a mean age of 59 years. Visual symptoms were the most common clinical presentation. There was complete or partial encasement of all 3 major cerebral arteries except for 3 cases in which only the anterior cerebral artery was not involved. The lateral wall of the cavernous sinus was invaded in 8 cases (67%) and the optic canal in 6 (50%). Complete resection was achieved in 2 cases (Simpson grades 2 and 3). In the remaining 10 cases of partial resection (Simpson grade 4), radical removal (> 90%) was achieved in 7 cases (70%). In the immediate postoperative period, there were no deaths. Four of 9 patients with visual deficits improved, while the 5 others remained unchanged. Two patients experienced transient neurological deficits. Other than an asymptomatic lacuna of the internal capsule, there were no ischemic lesions following surgery. Tumor recurrence occurred in 5 patients, between 24 and 168 months (mean 61 months) following surgery. CONCLUSIONS Although these giant lesions encasing major cerebral arteries are particularly treacherous for surgery, this series demonstrates that it is possible to safely achieve radical removal and at times even gross-total resection. However, the risk of recurrence remains high and larger studies are needed to see if and how improvement can be achieved, whether in surgical technique or technological advances, and by determining the timing and modality of adjuvant radiation therapy.
NASA Astrophysics Data System (ADS)
Bell, James F.; Olkin, Cathy; Castillo-Rogez, Julie
2015-11-01
Among the most potentially diagnostic but least explored populations of small bodies are the Jupiter Trojan asteroids, which orbit at ~5 AU in the L4 and L5 Lagrange points of Jupiter. The Trojans provide a unique perspective on solar system history, because their locations and physical, compositional, and mineralogic properties preserve evidence for important gravitational interactions among the giant planets. The locations and orbital properties of more than 6200 Jupiter Trojans are now known, but that is likely only a small fraction of a population of up to ~1e6 Trojans >1 km in size. The Trojans are hypothesized to be either former KBOs scattered into the inner solar system by early giant planet migration and then trapped in L4 and L5, or bodies formed near 5 AU in a more quiescent early solar system.Important Planetary Decadal Survey questions that can be addressed by studying the Trojans include: (a) How did the giant planets and their satellite systems accrete, and is there evidence that they migrated to new orbital positions? (b) What is the relationship between large and small KBOs? Is the small population derived by impact disruption of the large one? (c) What kinds of surface evolution, radiation chemistry, and surface-atmosphere interactions occur on distant icy primitive bodies? And (d) What are the sources of asteroid groups (Trojans and Centaurs) that remain to be explored by spacecraft?Here we describe the Trojan Tour and Rendezvous (TTR) New Frontiers mission concept, which is designed to answer these Decadal questions and to test hypotheses for early giant planet migration and solar system evolution. Via close flybys of many of these objects, and orbital characterization of at least one large Trojan, TTR will enable the initial up-close exploration of this population. Our primary mission goals are to characterize the overall surface geology, geochemistry and mineralogy of these worlds; to characterize their internal structure and dynamical properties; to investigate the nature, sources and history of activity on these bodies; and to explore the diversity of the broader Trojan asteroid population.
CARBON ABUNDANCES FOR RED GIANTS IN THE DRACO DWARF SPHEROIDAL GALAXY
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shetrone, Matthew D.; Stanford, Laura M.; Smith, Graeme H.
2013-05-15
Measurements of [C/Fe], [Ca/H], and [Fe/H] have been derived from Keck I LRISb spectra of 35 giants in the Draco dwarf spheroidal galaxy. The iron abundances are derived by a spectrum synthesis modeling of the wavelength region from 4850 to 5375 A, while calcium and carbon abundances are obtained by fitting the Ca II H and K lines and the CH G band, respectively. A range in metallicity of -2.9 {<=} [Fe/H] {<=} -1.6 is found within the giants sampled, with a good correlation between [Fe/H] and [Ca/H]. The great majority of stars in the sample would be classified asmore » having weak absorption in the {lambda}3883 CN band, with only a small scatter in band strengths at a given luminosity on the red giant branch. In this sense the behavior of CN among the Draco giants is consistent with the predominantly weak CN bands found among red giants in globular clusters of metallicity [Fe/H] < -1.8. Over half of the giants in the Draco sample have [Fe/H] > -2.25, and among these there is a trend for the [C/Fe] abundance to decrease with increasing luminosity on the red giant branch. This is a phenomenon that is also seen among both field and globular cluster giants of the Galactic halo, where it has been interpreted as a consequence of deep mixing of material between the base of the convective envelope and the outer limits of the hydrogen-burning shell. However, among the six Draco giants observed that turn out to have metallicities -2.65 < [Fe/H] < -2.25 there is no such trend seen in the carbon abundance. This may be due to small sample statistics or primordial inhomogeneities in carbon abundance among the most metal-poor Draco stars. We identify a potential carbon-rich extremely metal-poor star in our sample. This candidate will require follow-up observations for confirmation.« less
Fungal Cell Gigantism during Mammalian Infection
Zaragoza, Oscar; García-Rodas, Rocío; Nosanchuk, Joshua D.; Cuenca-Estrella, Manuel; Rodríguez-Tudela, Juan Luis; Casadevall, Arturo
2010-01-01
The interaction between fungal pathogens with the host frequently results in morphological changes, such as hyphae formation. The encapsulated pathogenic fungus Cryptococcus neoformans is not considered a dimorphic fungus, and is predominantly found in host tissues as round yeast cells. However, there is a specific morphological change associated with cryptococcal infection that involves an increase in capsule volume. We now report another morphological change whereby gigantic cells are formed in tissue. The paper reports the phenotypic characterization of giant cells isolated from infected mice and the cellular changes associated with giant cell formation. C. neoformans infection in mice resulted in the appearance of giant cells with cell bodies up to 30 µm in diameter and capsules resistant to stripping with γ-radiation and organic solvents. The proportion of giant cells ranged from 10 to 80% of the total lung fungal burden, depending on infection time, individual mice, and correlated with the type of immune response. When placed on agar, giant cells budded to produce small daughter cells that traversed the capsule of the mother cell at the speed of 20–50 m/h. Giant cells with dimensions that approximated those in vivo were observed in vitro after prolonged culture in minimal media, and were the oldest in the culture, suggesting that giant cell formation is an aging-dependent phenomenon. Giant cells recovered from mice displayed polyploidy, suggesting a mechanism by which gigantism results from cell cycle progression without cell fission. Giant cell formation was dependent on cAMP, but not on Ras1. Real-time imaging showed that giant cells were engaged, but not engulfed by phagocytic cells. We describe a remarkable new strategy for C. neoformans to evade the immune response by enlarging cell size, and suggest that gigantism results from replication without fission, a phenomenon that may also occur with other fungal pathogens. PMID:20585557
Resting site use of giant pandas in Wanglang Nature Reserve.
Kang, Dongwei; Wang, Xiaorong; Li, Junqing
2017-10-23
Little is known about the resting sites used by the giant panda (Ailuropoda melanoleuca), which restricts our understanding of their resting habits and limits conservation efforts. To enhance our understanding of resting site requirements and factors affecting the resting time of giant pandas, we investigated the characteristics of resting sites in the Wanglang Nature Reserve, Sichuan Province, China. The results indicated that the resting sites of giant pandas were characterised by a mean slope of 21°, mean nearest tree size of 53.75 cm, mean nearest shrub size of 2.82 cm, and mean nearest bamboo number of 56. We found that the resting sites were closer to bamboo than to trees and shrubs, suggesting that the resting site use of giant pandas is closely related to the presence of bamboo. Considering that giant pandas typically rest near a large-sized tree, protection of large trees in the forests is of considerable importance for the conservation of this species. Furthermore, slope was found to be an important factor affecting the resting time of giant pandas, as they tended to rest for a relatively longer time in sites with a smaller degree of slope.
Tun, Hein Min; Mauroo, Nathalie France; Yuen, Chan San; Ho, John Chi Wang; Wong, Mabel Ting; Leung, Frederick Chi-Ching
2014-01-01
Recent studies have described the bacterial community residing in the guts of giant pandas, together with the presence of lignocellulolytic enzymes. However, a more comprehensive understanding of the intestinal microbial composition and its functional capacity in giant pandas remains a major goal. Here, we conducted a comparison of bacterial, fungal and homoacetogenic microbial communities from fecal samples taken from two geriatric and two adult captive giant pandas. 16S rDNA amplicon pyrosequencing revealed that Firmicutes and Proteobacteria are the most abundant microbiota in both geriatric and adult giant pandas. However, members of phylum Actinobacteria found in adult giant pandas were absent in their geriatric counterparts. Similarly, ITS1 amplicon pyrosequencing identified developmental changes in the most abundant fungal classes from Sordariomycetes in adult pandas to Saccharomycetes in geriatric pandas. Geriatric pandas exhibited significantly higher abundance of a potential probiotic fungus (Candida tropicalis) as compared to adult pandas, indicating their importance in the normal digestive physiology of aged pandas. Our study also reported the presence of a lignocellulolytic white-rot fungus, Perenniporia medulla-panis, and the evidence of novel homoacetogens residing in the guts of giant pandas.
Tun, Hein Min; Mauroo, Nathalie France; Yuen, Chan San; Ho, John Chi Wang; Wong, Mabel Ting; Leung, Frederick Chi-Ching
2014-01-01
Recent studies have described the bacterial community residing in the guts of giant pandas, together with the presence of lignocellulolytic enzymes. However, a more comprehensive understanding of the intestinal microbial composition and its functional capacity in giant pandas remains a major goal. Here, we conducted a comparison of bacterial, fungal and homoacetogenic microbial communities from fecal samples taken from two geriatric and two adult captive giant pandas. 16S rDNA amplicon pyrosequencing revealed that Firmicutes and Proteobacteria are the most abundant microbiota in both geriatric and adult giant pandas. However, members of phylum Actinobacteria found in adult giant pandas were absent in their geriatric counterparts. Similarly, ITS1 amplicon pyrosequencing identified developmental changes in the most abundant fungal classes from Sordariomycetes in adult pandas to Saccharomycetes in geriatric pandas. Geriatric pandas exhibited significantly higher abundance of a potential probiotic fungus (Candida tropicalis) as compared to adult pandas, indicating their importance in the normal digestive physiology of aged pandas. Our study also reported the presence of a lignocellulolytic white-rot fungus, Perenniporia medulla-panis, and the evidence of novel homoacetogens residing in the guts of giant pandas. PMID:24475017
The magnetic fields at the surface of active single G-K giants
NASA Astrophysics Data System (ADS)
Aurière, M.; Konstantinova-Antova, R.; Charbonnel, C.; Wade, G. A.; Tsvetkova, S.; Petit, P.; Dintrans, B.; Drake, N. A.; Decressin, T.; Lagarde, N.; Donati, J.-F.; Roudier, T.; Lignières, F.; Schröder, K.-P.; Landstreet, J. D.; Lèbre, A.; Weiss, W. W.; Zahn, J.-P.
2015-02-01
Aims: We investigate the magnetic field at the surface of 48 red giants selected as promising for detection of Stokes V Zeeman signatures in their spectral lines. In our sample, 24 stars are identified from the literature as presenting moderate to strong signs of magnetic activity. An additional 7 stars are identified as those in which thermohaline mixing appears not to have occured, which could be due to hosting a strong magnetic field. Finally, we observed 17 additional very bright stars which enable a sensitive search to be performed with the spectropolarimetric technique. Methods: We use the spectropolarimeters Narval and ESPaDOnS to detect circular polarization within the photospheric absorption lines of our targets. We treat the spectropolarimetric data using the least-squares deconvolution method to create high signal-to-noise ratio mean Stokes V profiles. We also measure the classical S-index activity indicator for the Ca ii H&K lines, and the stellar radial velocity. To infer the evolutionary status of our giants and to interpret our results, we use state-of-the-art stellar evolutionary models with predictions of convective turnover times. Results: We unambiguously detect magnetic fields via Zeeman signatures in 29 of the 48 red giants in our sample. Zeeman signatures are found in all but one of the 24 red giants exhibiting signs of activity, as well as 6 out of 17 bright giant stars. However no detections were obtained in the 7 thermohaline deviant giants. The majority of the magnetically detected giants are either in the first dredge up phase or at the beginning of core He burning, i.e. phases when the convective turnover time is at a maximum: this corresponds to a "magnetic strip" for red giants in the Hertzsprung-Russell diagram. A close study of the 16 giants with known rotational periods shows that the measured magnetic field strength is tightly correlated with the rotational properties, namely to the rotational period and to the Rossby number Ro. Our results show that the magnetic fields of these giants are produced by a dynamo, possibly of α-ω origin since Ro is in general smaller than unity. Four stars for which the magnetic field is measured to be outstandingly strong with respect to that expected from the rotational period/magnetic field relation or their evolutionary status are interpreted as being probable descendants of magnetic Ap stars. In addition to the weak-field giant Pollux, 4 bright giants (Aldebaran, Alphard, Arcturus, η Psc) are detected with magnetic field strength at the sub-Gauss level. Besides Arcturus, these stars were not considered to be active giants before this study and are very similar in other respects to ordinary giants, with S-index indicating consistency with basal chromospheric flux. Tables 6-8 are available in electronic form at http://www.aanda.orgBased on observations obtained at the Télescope Bernard Lyot (TBL) at Observatoire du Pic du Midi, CNRS/INSU and Université de Toulouse, France, and at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council of Canada, CNRS/INSU and the University of Hawaii.
NASA Astrophysics Data System (ADS)
D'Angelo, G.; Durisen, R. H.; Lissauer, J. J.
2010-12-01
Gas giant planets play a fundamental role in shaping the orbital architecture of planetary systems and in affecting the delivery of volatile materials to terrestrial planets in the habitable zones. Current theories of gas giant planet formation rely on either of two mechanisms: the core accretion model and the disk instability model. In this chapter, we describe the essential principles upon which these models are built and discuss the successes and limitations of each model in explaining observational data of giant planets orbiting the Sun and other stars.
A β-Ta system for current induced magnetic switching in the absence of external magnetic field
NASA Astrophysics Data System (ADS)
Chen, Wenzhe; Qian, Lijuan; Xiao, Gang
2018-05-01
Magnetic switching via Giant Spin Hall Effect (GSHE) has received great interest for its role in developing future spintronics logic or memory devices. In this work, a new material system (i.e. a transition metal sandwiched between two ferromagnetic layers) with interlayer exchange coupling is introduced to realize the deterministic field-free perpendicular magnetic switching. This system uses β-Ta, as the GSHE agent to generate a spin current and as the interlayer exchange coupling medium to generate an internal field. The critical switching current density at zero field is on the order of 106 A/cm2 due to the large spin Hall angle of β-Ta. The internal field, along with switching efficiency, depends strongly on the orthogonal magnetization states of two ferromagnetic coupling layers in this system.
Conformation-controlled binding kinetics of antibodies
NASA Astrophysics Data System (ADS)
Galanti, Marta; Fanelli, Duccio; Piazza, Francesco
2016-01-01
Antibodies are large, extremely flexible molecules, whose internal dynamics is certainly key to their astounding ability to bind antigens of all sizes, from small hormones to giant viruses. In this paper, we build a shape-based coarse-grained model of IgG molecules and show that it can be used to generate 3D conformations in agreement with single-molecule Cryo-Electron Tomography data. Furthermore, we elaborate a theoretical model that can be solved exactly to compute the binding rate constant of a small antigen to an IgG in a prescribed 3D conformation. Our model shows that the antigen binding process is tightly related to the internal dynamics of the IgG. Our findings pave the way for further investigation of the subtle connection between the dynamics and the function of large, flexible multi-valent molecular machines.
NASA Astrophysics Data System (ADS)
Perna, Rosalba
2014-09-01
AXPs and SGRs are young neutron stars (NSs) characterized by high X-ray quiescent luminosities, outbursts, and sporadic giant flares (the SGRs). They are believed to be powered by ultra-strong B fields. However, the observation of outbursts from 'low-B' NSs has been a long-standing puzzle. Theoretical work by our group has shown that a) outbursts from a 'low-B' NS can be produced if the NS has a very strong internal toroidal field; b) a strong internal toroidal field can be revealed by spectral and timing analysis of the NS pulse profile. Here we propose to perform a detailed modeling of the spectra and pulse profile of the low-B magnetar SWIFT J1822.3-1606 with the aim of inferring its magnetic field topology and viewing geometry.
Spectroscopy of Six Red Giants in the Draco Dwarf Spheroidal Galaxy
NASA Astrophysics Data System (ADS)
Smith, Graeme H.; Siegel, Michael H.; Shetrone, Matthew D.; Winnick, Rebeccah
2006-10-01
Keck Observatory LRIS-B (Low Resolution Imaging Spectrometer) spectra are reported for six red giant stars in the Draco dwarf spheroidal galaxy and several comparison giants in the globular cluster M13. Indexes that quantify the strengths of the Ca II H and K lines, the λ3883 and λ4215 CN bands, and the λ4300 G band have been measured. These data confirm evidence of metallicity inhomogeneity within Draco obtained by previous authors. The four brightest giants in the sample have absolute magnitudes in the range -2.6
Giant pandas are not an evolutionary cul-de-sac: evidence from multidisciplinary research.
Wei, Fuwen; Hu, Yibo; Yan, Li; Nie, Yonggang; Wu, Qi; Zhang, Zejun
2015-01-01
The giant panda (Ailuropoda melanoleuca) is one of the world's most endangered mammals and remains threatened by environmental and anthropogenic pressure. It is commonly argued that giant pandas are an evolutionary cul-de-sac because of their specialized bamboo diet, phylogenetic changes in body size, small population, low genetic diversity, and low reproductive rate. This notion is incorrect, arose from a poor understanding or appreciation of giant panda biology, and is in need of correction. In this review, we summarize research across morphology, ecology, and genetics to dispel the idea, once and for all, that giant pandas are evolutionary dead-end. The latest and most advanced research shows that giant pandas are successful animals highly adapted to a specialized bamboo diet via morphological, ecological, and genetic adaptations and coadaptation of gut microbiota. We also debunk misconceptions around population size, population growth rate, and genetic variation. During their evolutionary history spanning 8 My, giant pandas have survived diet specialization, massive bamboo flowering and die off, and rapid climate oscillations. Now, they are suffering from enormous human interference. Fortunately, continued conservation effort is greatly reducing impacts from anthropogenic interference and allowing giant panda populations and habitat to recover. Previous ideas of a giant panda evolutionary cul-de-sac resulted from an unsystematic and unsophisticated understanding of their biology and it is time to shed this baggage and focus on the survival and maintenance of this high-profile species. © The Author 2014. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
NASA Astrophysics Data System (ADS)
Anthony-Twarog, Barbara J.; Lee-Brown, Donald B.; Deliyannis, Constantine P.; Twarog, Bruce A.
2018-03-01
HYDRA spectra of 287 stars in the field of NGC 2506 from the turnoff through the giant branch are analyzed. With previous data, 22 are identified as probable binaries; 90 more are classified as potential non-members. Spectroscopic analyses of ∼60 red giants and slowly rotating turnoff stars using line equivalent widths and a neural network approach lead to [Fe/H] = ‑0.27 ± 0.07 (s.d.) and [Fe/H] = ‑0.27 ± 0.06 (s.d.), respectively. Li abundances are derived for 145 probable single-star members, 44 being upper limits. Among turnoff stars outside the Li-dip, A(Li) = 3.04 ± 0.16 (s.d.), with no trend with color, luminosity, or rotation speed. Evolving from the turnoff across the subgiant branch, there is a well-delineated decline to A(Li) ∼1.25 at the giant branch base, coupled with the rotational spindown from between ∼20 and 70 km s‑1 to less than 20 km s‑1 for stars entering the subgiant branch and beyond. A(Li) remains effectively constant from the giant branch base to the red giant clump level. A new member above the clump redefines the path of the first-ascent red giant branch; its Li is 0.6 dex below the first-ascent red giants. With one exception, all post-He-flash stars have upper limits to A(Li), at or below the level of the brightest first-ascent red giant. The patterns are in excellent qualitative agreement with the model predictions for low/intermediate-mass stars which undergo rotation-induced mixing at the turnoff and subgiant branch, first dredge-up, and thermohaline mixing beyond the red giant bump.
Giant cell lesion of the jaw as a presenting feature of Noonan syndrome.
Sinnott, Bridget P; Patel, Maya
2018-05-30
This is a case of a 20-year-old woman who presented with a left jaw mass which was resected and found to be a giant cell granuloma of the mandible. Her history and physical examination were suggestive for Noonan syndrome which was confirmed with genetic testing and the finding of a PTPN11 gene mutation which has rarely been associated with giant cell lesions of the jaw. Given her particular genetic mutation and the presence of a giant cell lesion, we present a case of Noonan-like/multiple giant cell lesion syndrome. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Innate predator recognition in giant pandas.
Du, Yiping; Huang, Yan; Zhang, Hemin; Li, Desheng; Yang, Bo; Wei, Ming; Zhou, Yingmin; Liu, Yang
2012-02-01
Innate predator recognition confers a survival advantage to prey animals. We investigate whether giant pandas exhibit innate predator recognition. We analyzed behavioral responses of 56 naive adult captive giant pandas (Ailuropoda melanoleuca), to urine from predators and non-predators and water control. Giant pandas performed more chemosensory investigation and displayed flehmen behaviors more frequently in response to predator urine compared to both non-predator urine and water control. Subjects also displayed certain defensive behaviors, as indicated by vigilance, and in certain cases, fleeing behaviors. Our results suggest that there is an innate component to predator recognition in captive giant pandas, although such recognition was only slight to moderate. These results have implications that may be applicable to the conservation and reintroduction of this endangered species.
Generation of double giant pulses in actively Q-switched lasers
NASA Astrophysics Data System (ADS)
Korobeynikova, A. P.; Shaikin, I. A.; Shaykin, A. A.; Koryukin, I. V.; Khazanov, E. A.
2018-04-01
Generation of a second giant pulse in a longitudinal mode neighbouring to the longitudinal mode possessing minimal losses is theoretically and experimentally studied in actively Q-switched lasers. A mathematical model is suggested for explaining the giant pulse generation in a laser with multiple longitudinal modes. The model makes allowance for not only a standing, but also a running wave for each cavity mode. Results of numerical simulation and data of experiments with a Nd : YLF laser explain the effect of second giant pulse generation in a neighbouring longitudinal mode. After a giant pulse in the mode with minimal losses is generated, the threshold for the neighbouring longitudinal mode is still exceeded due to the effect of burning holes in the population inversion spatial distribution.
Giant planets: Clues on current and past organic chemistry in the outer solar system
NASA Technical Reports Server (NTRS)
Pollack, James B.; Atreya, Sushil K.
1992-01-01
The giant planets of the outer solar system - Jupiter, Saturn, Uranus, and Neptune - were formed in the same flattened disk of gas and dust, the solar nebula, as the terrestrial planets were. Yet, the giant planets differ in some very fundamental ways from the terrestrial planets. Despite enormous differences, the giant planets are relevant to exobiology in general and the origin of life on the Earth in particular. The giant planets are described as they are today. Their basic properties and the chemistry occurring in their atmospheres is discussed. Theories of their origin are explored and aspects of these theories that may have relevance to exobiology and the origin of life on Earth are stressed.
Giant cell phlebitis: a potentially lethal clinical entity
Kunieda, Takeshige; Murayama, Masanori; Ikeda, Tsuneko; Yamakita, Noriyoshi
2012-01-01
An 83-year-old woman presented to us with a 4-week history of general malaise, subjective fever and lower abdominal pain. Despite the intravenous infusion of antibiotics, her blood results and physical condition worsened, resulting in her sudden death. Autopsy study revealed that the medium-sized veins of the mesentery were infiltrated by eosinophil granulocytes, lymphocytes, macrophages and multinucleated giant cells; however, the arteries were not involved. Microscopically, venous giant cell infiltration was observed in the gastrointestinal tract, bladder, retroperitoneal tissues and myocardium. The final diagnosis was giant cell phlebitis, a rare disease of unknown aetiology. This case demonstrates for the first time that giant cell phlebitis involving extra-abdominal organs, including hearts, can cause serious morbidity. PMID:22859384
[Giant idiopathic hydronephrosis: toward a two-step therapeutic approach].
Boudhaye, Taher Ismail; Sidimalek, Mohamed; Jdoud, Cheikhani
2017-01-01
Giant hydronephrosis is rare. It is usually caused by ureteropelvic junction syndrome. We here report the unusual case of a patient hospitalized with giant hydronephrosis associated with impaired general condition. Diagnosis was based on CT scan. The patient underwent deferred nephrectomy after percutaneous drainage.
The Ba 4d-4f giant dipole resonance in complex Ba/Si compounds
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sahle, Ch. J.; Sternemann, C.; Sternemann, H.
2014-08-06
The shape of the Ba 4d–4f giant dipole resonance is studied for Ba atoms embedded inside complex Si networks covering structures consisting of Si nanocages and nanotubes, i.e. the clathrate Ba 8Si 46, the complex compound BaSi 6, and the semiconducting BaSi 2. Here, non-resonant x-ray Raman scattering is used to investigate confinement effects on the shape of the giant resonance in the vicinity of the Ba NIV, V-edge. The distinct momentum transfer dependence of the spectra is analyzed and discussed. The measurements are compared to calculations of the giant resonance within time-dependent local density approximation in the dipole limit.more » No modulation of the giant resonance's shape for Ba atoms confined in different local environments was observed, in contrast to the calculations. The absence of such shape modulation for complex Ba/Si compounds is discussed providing important implications for further studies of giant resonance phenomena utilizing both theory and experiment.« less
The Ba 4d-4f giant dipole resonance in complex Ba/Si compounds
NASA Astrophysics Data System (ADS)
Sahle, Ch J.; Sternemann, C.; Sternemann, H.; Tse, J. S.; Gordon, R. A.; Desgreniers, S.; Maekawa, S.; Yamanaka, S.; Lehmkühler, F.; Wieland, D. C. F.; Mende, K.; Huotari, S.; Tolan, M.
2014-02-01
The shape of the Ba 4d-4f giant dipole resonance is studied for Ba atoms embedded inside complex Si networks covering structures consisting of Si nanocages and nanotubes, i.e. the clathrate Ba8Si46, the complex compound BaSi6, and the semiconducting BaSi2. Here, non-resonant x-ray Raman scattering is used to investigate confinement effects on the shape of the giant resonance in the vicinity of the Ba NIV, V-edge. The distinct momentum transfer dependence of the spectra is analyzed and discussed. The measurements are compared to calculations of the giant resonance within time-dependent local density approximation in the dipole limit. No modulation of the giant resonance’s shape for Ba atoms confined in different local environments was observed, in contrast to the calculations. The absence of such shape modulation for complex Ba/Si compounds is discussed providing important implications for further studies of giant resonance phenomena utilizing both theory and experiment.
Tao, Yaqiong; Zeng, Bo; Xu, Liu; Yue, Bisong; Yang, Dong; Zou, Fangdong
2010-01-01
Interferon-gamma (IFN-gamma) is the only member of type II IFN and is vital in the regulation of immune and inflammatory responses. Herein we report the cloning, expression, and sequence analysis of IFN-gamma from the giant panda (Ailuropoda melanoleuca). The open reading frame of this gene is 501 base pair in length and encodes a polypeptide consisting of 166 amino acids. All conserved N-linked glycosylation sites and cysteine residues among carnivores were found in the predicted amino acid sequence of the giant panda. Recombinant giant panda IFN-gamma with a V5 epitope and polyhistidine tag was expressed in HEK293 host cells and confirmed by Western blotting. Phylogenetic analysis of mammalian IFN-gamma-coding sequences indicated that the giant panda IFN-gamma was closest to that of carnivores, then to ungulates and dolphin, and shared a distant relationship with mouse and human. These results represent a first step into the study of IFN-gamma in giant panda.
Kurihara, Kensuke; Tamura, Mieko; Shohda, Koh-Ichiroh; Toyota, Taro; Suzuki, Kentaro; Sugawara, Tadashi
2011-09-04
The construction of a protocell from a materials point of view is important in understanding the origin of life. Both self-reproduction of a compartment and self-replication of an informational substance have been studied extensively, but these processes have typically been carried out independently, rather than linked to one another. Here, we demonstrate the amplification of DNA (encapsulated guest) within a self-reproducible cationic giant vesicle (host). With the addition of a vesicular membrane precursor, we observe the growth and spontaneous division of the giant vesicles, accompanied by distribution of the DNA to the daughter giant vesicles. In particular, amplification of the DNA accelerated the division of the giant vesicles. This means that self-replication of an informational substance has been linked to self-reproduction of a compartment through the interplay between polyanionic DNA and the cationic vesicular membrane. Our self-reproducing giant vesicle system therefore represents a step forward in the construction of an advanced model protocell.
Infection and Proliferation of Giant Viruses in Amoeba Cells.
Takemura, Masaharu
2016-01-01
Acanthamoeba polyphaga mimivirus, the first discovered giant virus with genome size and particle size much larger than previously discovered viruses, possesses several genes for translation and CRISPER Cas system-like defense mechanism against virophages, which co-infect amoeba cells with the giant virus and which inhibit giant virus proliferation. Mimiviruses infect amoeba cells by phagocytosis and release their DNA into amoeba cytoplasm through their stargate structure. After infection, giant virion factories (VFs) form in amoeba cytoplasm, followed by DNA replication and particle formation at peripheral regions of VF. Marseilleviruses, the smallest giant viruses, infect amoeba cells by phagocytosis or endocytosis, form larger VF than Mimivirus's VF in amoeba cytoplasm, and replicate their particles. Pandoraviruses found in 2013 have the largest genome size and particle size among all viruses ever found. Pandoraviruses infect amoeba cells by phagocytosis and release their DNA into amoeba cytoplasm through their mouth-like apical pores. The proliferation of Pandoraviruses occurs along with nucleus disruption. New virions form at the periphery of the region formerly occupied by the amoeba cell nucleus.
Scientific rationale and concepts for in situ probe exploration of Uranus and Neptune
NASA Astrophysics Data System (ADS)
Mousis, O.; Atkinson, D.; Amato, M.; Aslam, S.; Atreya, S.; Blanc, M.; Brugger, B.; Calcutt, S.; Cavalié, T.; Charnoz, S.; Coustenis, A.; Deleuil, M.; Dobrijevic, M.; Encrenaz, T.; Ferri, F.; Fletcher, L.; Guillot, T.; Hartogh, P.; Hofstadter, M.; Hueso, R.
2017-09-01
Uranus and Neptune, referred to as ice giants, are fundamentally different from the better-known gas giants (Jupiter and Saturn). Exploration of an ice giant system is a high-priority science objective, as these systems (including the magnetosphere, satellites, rings, atmosphere, and interior) challenge our understanding of planetary formation and evolution. The importance of the ice giants is reflected in NASA's 2011 Decadal Survey, comments from ESA's SSC in response to L2/L3 mission proposals and results of the 2017 NASA/ESA Ice Giants study. A crucial part of exploration of the ice giants is in situ sampling of the atmosphere via an atmospheric probe. A probe would bring insights in two broad themes: the formation history of our Solar System and the processes at play in planetary atmospheres. Here we summarize the science driver for in situ measurements at these two planets and discuss possible mission concepts that would be consistent with the constraints of ESA M-class missions.
Genetic interaction of Neuroglian and Semaphorin1a during guidance and synapse formation.
Godenschwege, Tanja A; Murphey, Rodney K
2009-01-01
We have previously demonstrated a function for Neuroglian and Semaphorin1a in Drosophila giant fiber circuit formation. Both molecules are required for guiding the giant fibers out of the brain and have distinct functions during giant synapse formation. In this study we characterized the effects of various combinations of Neuroglian and Semaphorin1a gain and loss of function backgrounds on giant fiber circuitry formation. We found that Neuroglian and Semaphorin1a genetically interact with each other during axon guidance as well as during synapse formation. Our experiments revealed that during pathfinding of the giant fibers out of the brain, Neuroglian function seems to be dependent on Semaphorin1a. In contrast, during giant fiber synapse formation we observed that Semaphorin1a signaling as a receptor can be altered by Neuroglian in the same cell. In summary, our findings suggest that Neuroglian and Semaphorin1a can regulate each other's function in cis and that the resultant signaling output is possibly different during guidance and synapse formation.
Habitat assessment for giant pandas in the Qinling Mountain region of China
Feng, Tian-Tian; Van Manen, Frank T.; Zhao, Na-Xun; Li, Ming; Wei, Fu-Wen
2009-01-01
Because habitat loss and fragmentation threaten giant pandas (Ailuropoda melanoleuca), habitat protection and restoration are important conservation measures for this endangered species. However, distribution and value of potential habitat to giant pandas on a regional scale are not fully known. Therefore, we identified and ranked giant panda habitat in Foping Nature Reserve, Guanyinshan Nature Reserve, and adjacent areas in the Qinling Mountains of China. We used Mahalanobis distance and 11 digital habitat layers to develop a multivariate habitat signature associated with 247 surveyed giant panda locations, which we then applied to the study region. We identified approximately 128 km2 of giant panda habitat in Foping Nature Reserve (43.6% of the reserve) and 49 km2 in Guanyinshan Nature Reserve (33.6% of the reserve). We defined core habitat areas by incorporating a minimum patch-size criterion (5.5 km2) based on home-range size. Percentage of core habitat area was higher in Foping Nature Reserve (41.8% of the reserve) than Guanyinshan Nature Reserve (26.3% of the reserve). Within the larger analysis region, Foping Nature Reserve contained 32.7% of all core habitat areas we identified, indicating regional importance of the reserve. We observed a negative relationship between distribution of core areas and presence of roads and small villages. Protection of giant panda habitat at lower elevations and improvement of habitat linkages among core habitat areas are important in a regional approach to giant panda conservation.
Mihm, Bernhard; Bergmann, Markus; Brück, Wolfgang; Probst-Cousin, Stefan
2014-06-01
To determine if the pattern of macrophage activation reflects differences in the pathogenesis and clinical presentation of giant cell arteritis and primary angiitis of the central nervous system, specimens of 10 patients with giant cell arteritis and five with primary angiitis of the central nervous system were immunohistochemically studied and the expression of the macrophage activation markers 27E10, MRP14, MRP8 and 25F9 was determined in the vasculitic infiltrates. Thus, a partly different expression pattern of macrophage activation markers in giant cell arteritis and primary angiitis of the central nervous system was observed. The group comparison revealed that giant cell arteritis cases had significantly higher numbers of acute activated MRP14-positive macrophages, whereas primary angiitis of the central nervous system is characterized by a tendency toward more MRP8-positive intermediate/late activated macrophages. Furthermore, in giant cell arteritis comparably fewer CD8-positive lymphocytes were observed. These observations suggest, that despite their histopathological similarities, giant cell arteritis and primary angiitis of the central nervous system appear to represent either distinct entities within the spectrum of granulomatous vasculitides or different stages of similar disease processes. Their discrete clinical presentation is reflected by different activation patterns of macrophages, which may characterize giant cell arteritis as a more acute process and primary angiitis of the central nervous system as a more advanced inflammatory process. © 2013 Japanese Society of Neuropathology.
Profile of microRNA in Giant Panda Blood: A Resource for Immune-Related and Novel microRNAs
Yang, Mingyu; Du, Lianming; Li, Wujiao; Shen, Fujun; Fan, Zhenxin; Jian, Zuoyi; Hou, Rong; Shen, Yongmei; Yue, Bisong; Zhang, Xiuyue
2015-01-01
The giant panda (Ailuropoda melanoleuca) is one of the world’s most beloved endangered mammals. Although the draft genome of this species had been assembled, little was known about the composition of its microRNAs (miRNAs) or their functional profiles. Recent studies demonstrated that changes in the expression of miRNAs are associated with immunity. In this study, miRNAs were extracted from the blood of four healthy giant pandas and sequenced by Illumina next generation sequencing technology. As determined by miRNA screening, a total of 276 conserved miRNAs and 51 novel putative miRNAs candidates were detected. After differential expression analysis, we noticed that the expressions of 7 miRNAs were significantly up-regulated in young giant pandas compared with that of adults. Moreover, 2 miRNAs were up-regulated in female giant pandas and 1 in the male individuals. Target gene prediction suggested that the miRNAs of giant panda might be relevant to the expressions of 4,602 downstream genes. Subseuqently, the predicted target genes were conducted to KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway analysis and we found that these genes were mainly involved in host immunity, including the Ras signaling pathway, the PI3K-Akt signaling pathway, and the MAPK signaling pathway. In conclusion, our results provide the first miRNA profiles of giant panda blood, and the predicted functional analyses may open an avenue for further study of giant panda immunity. PMID:26599861
Globally intertwined evolutionary history of giant barrel sponges
NASA Astrophysics Data System (ADS)
Swierts, Thomas; Peijnenburg, Katja T. C. A.; de Leeuw, Christiaan A.; Breeuwer, Johannes A. J.; Cleary, Daniel F. R.; de Voogd, Nicole J.
2017-09-01
Three species of giant barrel sponge are currently recognized in two distinct geographic regions, the tropical Atlantic and the Indo-Pacific. In this study, we used molecular techniques to study populations of giant barrel sponges across the globe and assessed whether the genetic structure of these populations agreed with current taxonomic consensus or, in contrast, whether there was evidence of cryptic species. Using molecular data, we assessed whether giant barrel sponges in each oceanic realm represented separate monophyletic lineages. Giant barrel sponges from 17 coral reef systems across the globe were sequenced for mitochondrial (partial CO1 and ATP6 genes) and nuclear (ATPsβ intron) DNA markers. In total, we obtained 395 combined sequences of the mitochondrial CO1 and ATP6 markers, which resulted in 17 different haplotypes. We compared a phylogenetic tree constructed from 285 alleles of the nuclear intron ATPsβ to the 17 mitochondrial haplotypes. Congruent patterns between mitochondrial and nuclear gene trees of giant barrel sponges provided evidence for the existence of multiple reproductively isolated species, particularly where they occurred in sympatry. The species complexes in the tropical Atlantic and the Indo-Pacific, however, do not form separate monophyletic lineages. This rules out the scenario that one species of giant barrel sponge developed into separate species complexes following geographic separation and instead suggests that multiple species of giant barrel sponges already existed prior to the physical separation of the Indo-Pacific and tropical Atlantic.
Profile of microRNA in Giant Panda Blood: A Resource for Immune-Related and Novel microRNAs.
Yang, Mingyu; Du, Lianming; Li, Wujiao; Shen, Fujun; Fan, Zhenxin; Jian, Zuoyi; Hou, Rong; Shen, Yongmei; Yue, Bisong; Zhang, Xiuyue
2015-01-01
The giant panda (Ailuropoda melanoleuca) is one of the world's most beloved endangered mammals. Although the draft genome of this species had been assembled, little was known about the composition of its microRNAs (miRNAs) or their functional profiles. Recent studies demonstrated that changes in the expression of miRNAs are associated with immunity. In this study, miRNAs were extracted from the blood of four healthy giant pandas and sequenced by Illumina next generation sequencing technology. As determined by miRNA screening, a total of 276 conserved miRNAs and 51 novel putative miRNAs candidates were detected. After differential expression analysis, we noticed that the expressions of 7 miRNAs were significantly up-regulated in young giant pandas compared with that of adults. Moreover, 2 miRNAs were up-regulated in female giant pandas and 1 in the male individuals. Target gene prediction suggested that the miRNAs of giant panda might be relevant to the expressions of 4,602 downstream genes. Subseuqently, the predicted target genes were conducted to KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway analysis and we found that these genes were mainly involved in host immunity, including the Ras signaling pathway, the PI3K-Akt signaling pathway, and the MAPK signaling pathway. In conclusion, our results provide the first miRNA profiles of giant panda blood, and the predicted functional analyses may open an avenue for further study of giant panda immunity.
Survival of habitable planets in unstable planetary systems
NASA Astrophysics Data System (ADS)
Carrera, Daniel; Davies, Melvyn B.; Johansen, Anders
2016-12-01
Many observed giant planets lie on eccentric orbits. Such orbits could be the result of strong scatterings with other giant planets. The same dynamical instability that produces these scatterings may also cause habitable planets in interior orbits to become ejected, destroyed, or be transported out of the habitable zone. We say that a habitable planet has resilient habitability if it is able to avoid ejections and collisions and its orbit remains inside the habitable zone. Here we model the orbital evolution of rocky planets in planetary systems where giant planets become dynamically unstable. We measure the resilience of habitable planets as a function of the observed, present-day masses and orbits of the giant planets. We find that the survival rate of habitable planets depends strongly on the giant planet architecture. Equal-mass planetary systems are far more destructive than systems with giant planets of unequal masses. We also establish a link with observation; we find that giant planets with present-day eccentricities higher than 0.4 almost never have a habitable interior planet. For a giant planet with a present-day eccentricity of 0.2 and semimajor axis of 5 au orbiting a Sun-like star, 50 per cent of the orbits in the habitable zone are resilient to the instability. As semimajor axis increases and eccentricity decreases, a higher fraction of habitable planets survive and remain habitable. However, if the habitable planet has rocky siblings, there is a significant risk of rocky planet collisions that would sterilize the planet.
Hunting the most distant stars in the Milky Way: methods and initial results
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bochanski, John J.; Willman, Beth; West, Andrew A.
2014-04-01
We present a new catalog of 404 M giant candidates found in the UKIRT Infrared Deep Sky Survey (UKIDSS). The 2400 deg{sup 2} available in the UKIDSS Large Area Survey Data Release 8 resolve M giants through a volume four times larger than that of the entire Two Micron All Sky Survey. Combining near-infrared photometry with optical photometry and proper motions from the Sloan Digital Sky Survey yields an M giant candidate catalog with less M dwarf and quasar contamination than previous searches for similarly distant M giants. Extensive follow-up spectroscopy of this sample will yield the first map ofmore » our Galaxy's outermost reaches over a large area of sky. Our initial spectroscopic follow-up of ∼30 bright candidates yielded the positive identification of five M giants at distances ∼20-90 kpc. Each of these confirmed M giants have positions and velocities consistent with the Sagittarius stream. The fainter M giant candidates in our sample have estimated photometric distances ∼200 kpc (assuming [Fe/H] = 0.0), but require further spectroscopic verification. The photometric distance estimates extend beyond the Milky Way's virial radius, and increase by ∼50% for each 0.5 dex decrease in assumed [Fe/H]. Given the number of M giant candidates, initial selection efficiency, and volume surveyed, we loosely estimate that at least one additional Sagittarius-like accretion event could have contributed to the hierarchical build-up of the Milky Way's outer halo.« less
Groves, David I.; Goldfarb, Richard J.; Santosh, M.
2016-01-01
In contrast to their province scale similarities, the different giant gold deposit styles show contrasting critical controls at the district to deposit scale. For orogenic gold deposits, the giants appear to have formed by conjunction of a greater number of parameters to those that control smaller deposits, with resultant geometrical and lithostratigraphic complexity as a guide to their location. There are few giant IRGS due to their inferior fluid-flux systems relative to orogenic gold deposits, and those few giants are essentially preservational exceptions. Many Carlin-type deposits are giants due to the exceptional conjunction of both structural and lithological parameters that caused reactive and permeable rocks, enriched in syngenetic gold, to be located below an impermeable cap along antiformal “trends”. Hydrocarbons probably played an important role in concentrating metal. The supergiant Post-Betze deposit has additional ore zones in strain heterogeneities surrounding the pre-gold Goldstrike stock. All unequivocal IOCG deposits are giant or near-giant deposits in terms of gold-equivalent resources, partly due to economic factors for this relatively poorly understood, low Cu-Au grade deposit type. The supergiant Olympic Dam deposit, the most shallowly formed deposit among the larger IOCGs, probably owes its origin to eruption of volatile-rich hybrid magma at surface, with formation of a large maar and intense and widespread brecciation, alteration and Cu-Au-U deposition in a huge rock volume.
NASA Astrophysics Data System (ADS)
Danis-Wlodarczyk, Katarzyna; Vandenheuvel, Dieter; Jang, Ho Bin; Briers, Yves; Olszak, Tomasz; Arabski, Michal; Wasik, Slawomir; Drabik, Marcin; Higgins, Gerard; Tyrrell, Jean; Harvey, Brian J.; Noben, Jean-Paul; Lavigne, Rob; Drulis-Kawa, Zuzanna
2016-06-01
Bacteriophage therapy is currently resurging as a potential complement/alternative to antibiotic treatment. However, preclinical evaluation lacks streamlined approaches. We here focus on preclinical approaches which have been implemented to assess bacteriophage efficacy against Pseudomonas biofilms and infections. Laser interferometry and profilometry were applied to measure biofilm matrix permeability and surface geometry changes, respectively. These biophysical approaches were combined with an advanced Airway Surface Liquid infection model, which mimics in vitro the normal and CF lung environments, and an in vivo Galleria larvae model. These assays have been implemented to analyze KTN4 (279,593 bp dsDNA genome), a type-IV pili dependent, giant phage resembling phiKZ. Upon contact, KTN4 immediately disrupts the P. aeruginosa PAO1 biofilm and reduces pyocyanin and siderophore production. The gentamicin exclusion assay on NuLi-1 and CuFi-1 cell lines revealed the decrease of extracellular bacterial load between 4 and 7 logs and successfully prevents wild-type Pseudomonas internalization into CF epithelial cells. These properties and the significant rescue of Galleria larvae indicate that giant KTN4 phage is a suitable candidate for in vivo phage therapy evaluation for lung infection applications.
The Unusual S Star Binary HD 191589
NASA Technical Reports Server (NTRS)
Ake, Thomas B.; Johnson, Hollis R.; Wahlgren, Glenn M.; Jorissen, Alain
1996-01-01
Recently, we discovered with International Ultraviolet Explorer (IUE) an F0-F2 IV-V companion to the T(sub c)-deficient S star HD 191589. If the magnitude difference is (delta)V=3.7, as indicated by several arguments, and E(B-V) = 0.0, we obtain a value of M(sub v)= - 1.5 +/- 0.4 for the Peculiar Red Giant (PRG), too faint for it to be a thermally-pulsing asymptotic giant branch star. According to the binary mass-transfer hypothesis for T(sub c)-deficient PRG's, a white dwarf must be the source of the s-process enhancement of the current primary star, but it cannot be seen because of the presence of the secondary. If such is the case, the F-star companion may also have been contaminated by s-process material. High-dispersion IUE observations indicate an enhancement of Zr II in the photosphere of the F-star as well. Thus, HD 191589 is likely a triple system, where what was once the most massive component of the system has polluted both of its companions with s-process material. One of these is the current S star, while the other is the companion still near the main sequence.
A prevalence of dynamo-generated magnetic fields in the cores of intermediate-mass stars.
Stello, Dennis; Cantiello, Matteo; Fuller, Jim; Huber, Daniel; García, Rafael A; Bedding, Timothy R; Bildsten, Lars; Aguirre, Victor Silva
2016-01-21
Magnetic fields play a part in almost all stages of stellar evolution. Most low-mass stars, including the Sun, show surface fields that are generated by dynamo processes in their convective envelopes. Intermediate-mass stars do not have deep convective envelopes, although 10 per cent exhibit strong surface fields that are presumed to be residuals from the star formation process. These stars do have convective cores that might produce internal magnetic fields, and these fields might survive into later stages of stellar evolution, but information has been limited by our inability to measure the fields below the stellar surface. Here we report the strength of dipolar oscillation modes for a sample of 3,600 red giant stars. About 20 per cent of our sample show mode suppression, by strong magnetic fields in the cores, but this fraction is a strong function of mass. Strong core fields occur only in red giants heavier than 1.1 solar masses, and the occurrence rate is at least 50 per cent for intermediate-mass stars (1.6-2.0 solar masses), indicating that powerful dynamos were very common in the previously convective cores of these stars.
CARBON STARS IN THE SATELLITES AND HALO OF M31
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hamren, Katherine; Guhathakurta, Puragra; Rockosi, Constance M.
2016-09-01
We spectroscopically identify a sample of carbon stars in the satellites and halo of M31 using moderate-resolution optical spectroscopy from the Spectroscopic and Photometric Landscape of Andromeda’s Stellar Halo survey. We present the photometric properties of our sample of 41 stars, including their brightness with respect to the tip of the red giant branch (TRGB) and their distributions in various color–color spaces. This analysis reveals a bluer population of carbon stars fainter than the TRGB and a redder population of carbon stars brighter than the TRGB. We then apply principal component analysis to determine the sample’s eigenspectra and eigencoefficients. Correlatingmore » the eigencoefficients with various observable properties reveals the spectral features that trace effective temperature and metallicity. Putting the spectroscopic and photometric information together, we find the carbon stars in the satellites and halo of M31 to be minimally impacted by dust and internal dynamics. We also find that while there is evidence to suggest that the sub-TRGB stars are extrinsic in origin, it is also possible that they are are particularly faint members of the asymptotic giant branch.« less
Planetary Interiors: Parametric Modeling of Global Geophysical Properties
NASA Astrophysics Data System (ADS)
Montgomery, W.; Jeanloz, R.
2004-12-01
Taking into account a realistic form of equation of state, we parameterize the degree to which bulk geophysical properties of planets are sensitive to gravitational self-compression. For example, the normalized moment of mass of a uniform-composition planet is C/Ma2 = 0.40 only in the limit of zero planetary size or incompressible material, and decreases toward 0.32 for finite compressibility as the planetary radius increases toward a = 104 km (M is planetary mass). Central density correspondingly increases from ρ 0, the surface density, toward 10 * ρ 0. Our calculations, based on the Eulerian finite-strain equation of state, make it possible to distinguish the effects of self-compression from the effects of non-uniformity (due either to changes in bulk composition or in phase with depth) as these influence planetary mass and moment of inertia relative to size. As observations of extra-solar planets can provide estimates of their mass and diameter (hence mean density), our formulation can account for the effects of compression in modeling the internal constitution and evolution of these objects. The effects of compression are especially important for giant and super-giant planets, such as the majority that have been observed to date.
Santos, Jaime Martinez; Kaderali, Zul; Spears, Julian; Rubin, Laurence A; Marotta, Thomas R
2015-05-29
Intracranial aneurysms in polyarteritis nodosa (PAN) are exceedingly rare lesions with unpredictable behavior that pose real challenges to microsurgical and endovascular interventions owing to their inflammatory nature. We introduce a safe and effective alternative for treating these aneurysms using Pipeline embolization devices (PEDs). A 20-year-old man presented with diplopia, headaches, chronic abdominal pain, and weight loss. Diagnostic evaluations confirmed PAN, including bilateral giant cavernous carotid aneurysms. Cyclophosphamide and steroids achieved significant and sustained clinical improvement, with a decision to follow the aneurysms serially. Seven years later the left unruptured aneurysm enlarged, causing a sudden severe headache and a cavernous sinus syndrome. Treatment of the symptomatic aneurysm was pursued using flow diversion (PED) and the internal carotid artery was successfully reconstructed with a total of four overlapping PEDs. At 6 months follow-up, complete exclusion of the aneurysm was demonstrated, with symptomatic recovery. This is the first description of using a flow-diverting technique in an inflammatory vasculitis. In this case, PEDs not only attained a definitive closure of the aneurysm but also reconstructed the damaged and fragile arterial segment affected with vasculitis. 2015 BMJ Publishing Group Ltd.
Atmospheres of the Giant Planets
NASA Technical Reports Server (NTRS)
Ingersoll, Andrew P.
2002-01-01
The giant planets, Jupiter, Saturn, Uranus, and Neptune, are fluid objects. They have no solid surfaces because the light elements constituting them do not condense at solar-system temperatures. Instead, their deep atmospheres grade downward until the distinction between gas and liquid becomes meaningless. The preceding chapter delved into the hot, dark interiors of the Jovian planets. This one focuses on their atmospheres, especially the observable layers from the base of the clouds to the edge of space. These veneers arc only a few hundred kilometers thick, less than one percent of each planet's radius, but they exhibit an incredible variety of dynamic phenomena. The mixtures of elements in these outer layers resemble a cooled-down piece of the Sun. Clouds precipitate out of this gaseous soup in a variety of colors. The cloud patterns are organized by winds, which are powered by heat derived from sunlight (as on Earth) and by internal heat left over from planetary formation. Thus the atmospheres of the Jovian planets are distinctly different both compositionally and dynamically from those of the terrestrial planets. Such differences make them fascinating objects for study, providing clues about the origin and evolution of the planets and the formation of the solar system.
International Ultraviolet Explorer (IUE) ultraviolet spectral atlas of selected astronomical objects
NASA Technical Reports Server (NTRS)
Wu, Chi-Chao; Reichert, Gail A.; Ake, Thomas B.; Boggess, Albert; Holm, Albert V.; Imhoff, Catherine L.; Kondo, Yoji; Mead, Jaylee M.; Shore, Steven N.
1992-01-01
The IUE Ultraviolet Spectral Atlas of Selected Astronomical Objects (or 'the Atlas'), is based on the data that were available in the IUE archive in 1986, and is intended to be a quick reference for the ultraviolet spectra of many categories of astronomical objects. It shows reflected sunlight from the Moon, planets, and asteroids, and also shows emission from comets. Comprehensive compilations of UV spectra for main sequence, subgiant, giant, bright giant, and supergiant stars are published elsewhere. This Atlas contains the spectra for objects occupying other areas of the Hertzsprung-Russell diagram: pre-main sequence stars, chemically peculiar stars, pulsating variables, subluminous stars, and Wolf-Rayet stars. This Atlas also presents phenomena such as the chromospheric and transition region emissions from late-type stars; composite spectra of stars, gas streams, accretion disks and gas envelopes of binary systems; the behavior of gas ejecta shortly after the outburst of novac and supernovac; and the H II regions, planetary nebulae, and supernova remnants. Population 2 stars, globular clusters, and luminous stars in the Magellanic Clouds, M31, and M33, are also included in this publication. Finally, the Atlas gives the ultraviolet spectra of galaxies of different Hubble types and of active galaxies.
NASA Astrophysics Data System (ADS)
Li, Wei; Alves, Tiago M.; Wu, Shiguo; Rebesco, Michele; Zhao, Fang; Mi, Lijun; Ma, Benjun
2016-10-01
A giant submarine creep zone exceeding 800 km2 on the continental slope offshore the Dongsha Islands, South China Sea, is investigated using bathymetric and 3D seismic data tied to borehole information. The submarine creep zone is identified as a wide area of seafloor undulations with ridges and troughs. The troughs form NW- and WNW-trending elongated depressions separating distinct seafloor ridges, which are parallel or sub-parallel to the continental slope. The troughs are 0.8-4.7 km-long and 0.4 to 2.1 km-wide. The ridges have wavelengths of 1-4 km and vertical relief of 10-30 m. Slope strata are characterised by the presence of vertically stacked ridges and troughs at different stratigraphic depths, but remaining relatively stationary in their position. The interpreted ridges and troughs are associated with large-scale submarine creep, and the troughs can be divided into three types based on their different internal characters and formation processes. The large-scale listric faults trending downslope below MTD 1 and horizon T0 may be the potential glide planes for the submarine creep movement. High sedimentation rates, local fault activity and the frequent earthquakes recorded on the margin are considered as the main factors controlling the formation of this giant submarine creep zone. Our results are important to the understanding of sediment instability on continental slopes as: a) the interpreted submarine creep is young, or even active at present, and b) areas of creeping may evolve into large-scale slope instabilities, as recorded by similar large-scale events in the past.
Solid variant of aneurysmal bone cyst of the left parietal bone without preceding trauma.
Nestler, Ulf; Wagner, Hans-Joachim; Schaenzer, Anne; Preuss, Matthias
2013-12-01
We report the case of a 17-year-old girl with an indolent, smooth swelling of the left cranial vault that had been developing for 2 months. Complete surgical excision was performed and the defect was closed using artificial bone cement. The integrity of the dura mater was conserved and the patient recovered without neurological deficit. Magnetic resonance imaging (MRI) controls 6 and 18 months after the operation did not find signs of recurrence. The lesion consisted of an elastic bone shell containing bony trabeculae with soft brown-greyish tissue and posthemorrhagic dark fluid. Histological assessment found CD68 positive multinucleated giant cells in a highly cellular fibroblastic matrix surrounding bony lamellar structures, without signs of inflammation or malignancy. Hyperparathyroidism was ruled out by normal serum values for parathyroid hormone, calcium, phosphate, and alkaline phosphatase. Histologically, first diagnosis was giant cell reparative granuloma and reference pathology disclosed aneurysmal bone cyst. The solid variant of aneurysmal bone cyst and the giant cell reparative granuloma can be histologically indistinguishable. Both lesions are only rarely encountered in cranial bones and most published cases affected the cranial base or the jaw, mainly in children or young adults. From a clinical point of view, classification into "outward" lesions (osteolysis of external parts of the vault with preservation of internal tabula) and "inward" lesions (intracranial multicystic lesions with raise of intracranial pressure) has been proposed. Three phases of development can be identified, and spontaneous involution has been described. Both entities are benign, but because in several cases an underlying malignant disease has been found, complete resection and regular follow-up by MRI are recommended. Georg Thieme Verlag KG Stuttgart · New York.
NASA Technical Reports Server (NTRS)
Lupu, R. E.; Marley, M. S.; Lewis, N.; Line, M.; Traub, W.; Zahnle, K.
2016-01-01
Reflected light spectroscopy and photometry of cool, directly imaged extrasolar giant planets are expected to be performed in the next decade by space-based telescopes equipped with optical wavelength coronagraphs and integral field spectrographs, such as the Wide-Field Infrared Survey Telescope (WFIRST). We are developing a new atmospheric retrieval methodology to help assess the science return and inform the instrument design for such future missions, and ultimately interpret the resulting observations. Our retrieval technique employs an albedo model coupled with both a Markov chain Monte Carlo Ensemble Sampler (emcee) and a multimodal nested sampling algorithm (MultiNest) to map the posterior distribution. This combination makes the global evidence calculation more robust for any given model, and highlights possible discrepancies in the likelihood maps. Here we apply this methodology to simulated spectra of cool giant planets. As a proof-of-concept, our current atmospheric model contains 1 or 2 cloud layers, methane as a major absorber, and a H2-He background gas. This 6-to-9 parameter model is appropriate for Jupiter-like planets and can be easily expanded in the future. In addition to deriving the marginal likelihood distribution and confidence intervals for the model parameters, we perform model selection to determine the significance of methane and cloud detection as a function of expected signal-to-noise, in the presence of spectral noise correlations. After internal validation, the method is applied to realistic reflected-light spectra of Jupiter, Saturn, and HD 99492 c, a likely observing target. We find that the presence or absence of clouds and methane can be determined with high accuracy, while parameters uncertainties are model-dependent.
NASA Astrophysics Data System (ADS)
Kraus, Dominik
2017-10-01
Carbon-hydrogen demixing and subsequent diamond precipitation has been predicted to strongly participate in shaping the internal structure and evolution of icy giant planets like Neptune and Uranus. The very same dense plasma chemistry is also a potential concern for CH plastic ablator materials in inertial confinement fusion (ICF) experiments where similar conditions are present during the first compression stage of the imploding capsule. Here, carbon-hydrogen demixing may enhance the hydrodynamic instabilities occurring in the following compression stages. First experiments applying dynamic compression and ultrafast in situ X-ray diffraction at SLAC's Linac Coherent Light Source demonstrated diamond formation from polystyrene (CH) at 150 GPa and 5000 K. Very recent experiments have now investigated the influence of oxygen, which is highly abundant in icy giant planets on the phase separation process. Compressing PET (C5H4O2) and PMMA(C5H8O2), we find again diamond formation at pressures above 150 GPa and temperatures of several thousand kelvins, showing no strong effect due to the presence of oxygen. Thus, diamond precipitation deep inside icy giant planets seems very likely. Moreover, small-angle X-ray scattering (SAXS) was added to the platform, which determines an upper limit for the diamond particle size, while the width of the diffraction features provides a lower limit. We find that diamond particles of several nanometers in size are formed on a nanosecond timescale. Finally, spectrally resolved X-ray scattering is used to scale amorphous diffraction signals and allows for determining the amount of carbon-hydrogen demixing inside the compressed samples even if no crystalline diamond is formed. This whole set of diagnostics provides unprecedented insights into the nanosecond kinetics of dense plasma chemistry.
Engineering a Solution to Jupiter Exploration
NASA Technical Reports Server (NTRS)
Clark, Karla; Magner, Thomas; Lisano, Michael; Pappalardo, Robert
2010-01-01
The Europa Jupiter System Mission (EJSM) would be an international mission with the overall theme of investigating the emergence of habitable worlds around gas giants. Its goals are to (1) explore Europa to investigate its habitability, (2) characterize Ganymede as a planetary object including its potential habitability and (3) explore the Jupiter system as an archetype for gas giants. NASA and ESA have concluded a detailed joint study of a mission to Europa, Ganymede, and the Jupiter system with conceptual orbiters developed by NASA and ESA. The baseline EJSM architecture consists of two primary elements operating simultaneously in the Jovian system: the NASA-led Jupiter Europa Orbiter (JEO), and the ESA-led Jupiter Ganymede Orbiter (JGO). JEO and JGO would execute an intricately choreographed exploration of the Jupiter System before settling into orbit around Europa and Ganymede, respectively. EJSM would directly address themes concerning the origin and evolution of satellite systems and water-rich environments in icy satellites. The potential habitability of the ocean-bearing moons Europa and Ganymede would be investigated, by characterizing the geophysical, compositional, geological, and external processes that affect these icy worlds. EJSM would also investigate Io and Callisto, Jupiter's atmosphere, and the Jovian magnetosphere. By understanding the Jupiter system and unraveling its history, the formation and evolution of gas giant planets and their satellites would be better known. Most importantly, EJSM would shed new light on the potential for the emergence of life in the celestial neighborhood and beyond. The EJSM baseline architecture would provide opportunities for coordinated synergistic observations by JEO and JGO of the Jupiter and Ganymede magnetospheres, the volcanoes and torus of Io, the atmosphere of Jupiter, and comparative planetology of icy satellites. Each spacecraft would conduct both synergistic dual-spacecraft investigations and stand-alone measurements toward the overall mission theme and goals.
NASA Astrophysics Data System (ADS)
Gromig, R.; Lebas, E.; Krastel, S.; Averes, T.; Wagner, B.; Melles, M.; Fedorov, G.
2017-12-01
In the framework of the German-Russian project `PLOT - Paleolimnological Transect' (for an overview of the project see Gromig et al., this meeting), a pilot seismic survey was carried out in Lake Ladoga (Russia) in late summer 2013. In total, 1500 km of seismic reflection profiles have been acquired using a mini-GI gun and a 32-channel seismic streamer. The high-resolution of the seismic data allows us to document in detail the sedimentary processes that occurred in the lake during the preglacial and postglacial history. The seismic stratigraphic architecture of the lake shows, from top to bottom, acoustically well-stratified Holocene muds overlaying rather transparent postglacial varves. These sediment successions are usually bordered by a hard reflector underneath, which may represent coarse-grained sediments or a till. The nature of the material composing the uppermost units have been tied to coring information from core Co1309, which was retrieved during the same survey. Of particular interest, are the single to composite, giant (kilometer-scale) mounds directly overlying the hard reflector. Internal architecture of the mounds reveals a complex formation history, with mound types showing significant structural deformation of different degrees; and other mound types showing a central deformation area, which strongly contrasts with the titled reflections or undisturbed stratification visible at the edges. The deepest seismic unit underlying the mounds is characterized by well-bedded, tilted reflectors in the southeastern part of the lake, while clear synclines are identified in the northwestern part of the lake. An erosional truncation separates the deepest unit from the overlying ones. In the work presented here, we focus on the understanding of the origin and the formation of the giant mounds with respect to the glacial history of Lake Ladoga.
The ODINUS Mission Concept: a Mission for the exploration the Ice Giant Planets
NASA Astrophysics Data System (ADS)
Peron, Roberto
We present the scientific case and the mission concept of a proposal for the the comparative exploration of the ice giant planets Uranus and Neptune and their satellites with a pair of twin spacecraft: ODINUS (Origins, Dynamics and Interiors of Neptunian and Uranian Systems). The ODINUS proposal was submitted in response to the call for white papers for the definition of the themes of the L2 and L3 mission in the framework of ESA Cosmic Vision 2015-2025 program. The goal of ODINUS is the advancement of our understanding of the ancient past of the Solar System and, more generally, of how planetary systems form and evolve. The mission concept is focused on providing elements to answer to the scientific themes of the Cosmic Vision 2015-2025 program: What are the conditions for planetary formation and the emergency of life? How does the Solar System work? What are the fundamental physical laws of the Universe? In order to achieve its goals, ODINUS foresees the use of two twin spacecraft to be placed in orbit around Uranus and Neptune respectively, with selected flybys of their satellites. The proposed measurements aim to study the atmospheres and magnetospheres of the planets, the surfaces of the satellites, and the interior structure and composition of both satellites and planets. An important possibility for performing fundamental physics studies (among them tests of general relativity theory) is offered by the cruise phase. After the extremely positive evaluation of ESA Senior Survey Committee, who stated that ``the exploration of the icy giants appears to be a timely milestone, fully appropriate for an L class mission'', we discuss strategies to comparatively study Uranus and Neptune with future international missions.
The ODINUS Mission Concept: a Mission to the Ice Giant Planets
NASA Astrophysics Data System (ADS)
Turrini, Diego; Politi, Romolo; Peron, Roberto; Grassi, Davide; Plainaki, Christina; Barbieri, Mauro; Massimo Lucchesi, David; Magni, Gianfranco; Altieri, Francesca; Cottini, Valeria; Gorius, Nicolas; Gaulme, Patrick; Schmider, François-Xavier; Adriani, Alberto; Piccioni, Giuseppe
2014-05-01
We present the scientific case and the mission concept for the comparative exploration of the ice giant planets Uranus and Neptune and their satellites with a pair of twin spacecraft: ODINUS (Origins, Dynamics and Interiors of Neptunian and Uranian Systems). The ODINUS proposal was submitted in response to the call for white papers for the definition of the themes of the L2 and L3 mission in the framework of the ESA Cosmic Vision 2015-2025 program. The goal of ODINUS is the advancement of our understanding of the ancient past of the Solar System and, more generally, of how planetary systems form and evolve. The mission concept is focused on providing elements to answer to the scientific themes of the Cosmic Vision 2015-2025 program: What are the conditions for planetary formation and the emergency of life? How does the Solar System work? What are the fundamental physical laws of the Universe? In order to achieve its goals, the ODINUS mission concept proposed the use of two twin spacecraft to be put in orbit around Uranus and Neptune respectively, with selected flybys of their satellites. The proposed measurements aim to study the atmospheres and magnetospheres of the planets, the surfaces of the satellites, and the interior structure and composition of both satellites and planets. An important possibility for performing fundamental physics studies (among them tests of general relativity theory) is offered by the cruise phase. After the extremely positive evaluation of ESA Senior Survey Committee, who stated that 'the exploration of the icy giants appears to be a timely milestone, fully appropriate for an L class mission', we discuss strategies to comparatively study Uranus and Neptune with future international missions.
Crowley, R Webster; Abla, Adib A; Ducruet, Andrew F; McDougall, Cameron G; Albuquerque, Felipe C
2014-07-01
Flow-diverting stents represent a substantial advancement in the treatment of cerebral aneurysms. They can, however, be associated with unique complications that may require management through adjunctive techniques. To present a technical report of a salvage technique used to realign a prolapsed Pipeline Embolization Device (PED) during the treatment of a giant internal carotid artery (ICA) aneurysm. A patient in his late 70s with an incidental giant supraclinoid ICA aneurysm presented for endovascular consideration. Treatment was planned using the PED. Following placement of the device there were two focal areas of incomplete expansion and balloon angioplasty was performed. This manipulation resulted in foreshortening of the distal aspect of the PED which caused the device to prolapse into the aneurysm. After multiple unsuccessful attempts to regain distal access, a salvage technique was attempted in which a balloon was inflated in the middle cerebral artery and, by applying traction, the PED was realigned with the parent artery. After the PED was realigned, direct distal catheter access was achieved and a second Pipeline device was deployed, successfully covering the aneurysm neck with resultant flow stasis. The patient had no postoperative issues and was discharged 2 days later without deficit. The balloon-anchoring technique was successfully used to realign a PED that had prolapsed into a giant ICA aneurysm. This maneuver prevented potentially disastrous complications and allowed the satisfactory completion of the aneurysm embolization. This represents a useful salvage technique that should be considered when encountering a prolapsed stent. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
NASA Astrophysics Data System (ADS)
Wang, M. D.; Li, D. S.; Huang, Y.; Zhang, C.; Zhong, K. M.; Sun, L. N.
2013-08-01
In the notebook and clamshell mobile phone, data communication wire often requires repeated bending. Generally, communication wire with the actual application conditions, the test data cannot assess bending resistance performance of data communication wire is tested conventionally using wires with weights of 90 degree to test bending number, this test method and device is not fully reflect the fatigue performance in high frequency and light load application condition, at the same time it has a large difference between the test data of the long-term reliability of high frequency and low load conditions. In this paper, high frequency light load fatigue testing machine based on the giant magnetostrictive material and stroke multiplier is put forward, in which internal reflux stroke multiplier is driven by giant magnetostrictive material to realize the rapid movement of light load. This fatigue testing device has the following advantages: (1) When the load is far less than the friction, reducing friction is very effective to improve the device performance. Because the body is symmetrical, the friction loss of radial does not exist in theory, so the stress situation of mechanism is good with high transmission efficiency and long service life. (2) The installation position of the output hydraulic cylinder, can be arranged conveniently as ordinary cylinder. (3) Reciprocating frequency, displacement and speed of high frequency movement can be programmed easily to change with higher position precision. (4)Hydraulic oil in this device is closed to transmit, which does not produce any environment pollution. The device has no hydraulic pump and tank, and less energy conversion processes, so it is with the trend of green manufacturing.
NASA Astrophysics Data System (ADS)
Ren, He
Molecular architectures and topologies are found contributing to the formation of supramolecular structures of giant molecules. Dr. Cheng's research group developed a diverse of giant molecules via precisely controlled chemistry synthetic routes. These giant molecules can be categorized into several different families, namely giant surfactants, giant shape amphiphiles and giant polyhedron. By analyzing the hierarchical structures of these carefully designed and precisely synthesized giant molecules, the structural factors which affect, or even dominates, in some cases, the formation of supramolecular structures are revealed in these intensive researches. The results will further contribute to the understanding of dependence of supramolecular structures on molecular designs as well as molecular topology, and providing a practical solution to the scaling up of microscopic molecular functionalities to macroscopic material properties. Molecular Nano Particles (MNPs), including fullerene (C60), POSS, Polyoxometalate (POM) and proteins etc., is defined and applied as a specific type of building blocks in the design and synthesis of giant molecules. The persistence in shape and symmetry is considered as one of the major properties of MNPs. This persistence will support the construction of giant molecules for further supramolecular structures' study by introducing specific shapes, or precisely located side groups which will facilitate self-assembling behaviors with pre-programmed secondary interactions. Dictating material physical properties by its chemical composition is an attractive yet currently failed approach in the study of materials. However, the pursuit of determining material properties by microscopic molecular level properties is never seized, and found its solution when the idea of crystal engineering is raised: should each atom in the material is located exactly where it is designed to be and is properly bonded, the property of the material is hence determined. In such "bottom-up" approach, the precise fabrication of 2 nm 100 nm nanostructures, is of great research interest. In this thesis, crystal engineering of giant molecules based on PDI conjugated POSS Nano-Atom (PDI-BPOSS) nano-atoms via self-assembly is performed and studied. Herein, three different giant molecules were synthesized: shape amphiphile, m-phenyl-(PDI-BPOSS)2 (S1) and tetrahedron, R-(PDI-BPOSS)4 (S2) and S-(PDI-BPOSS)4 (S3). Single crystals were grown for S1 and S2, X-ray diffraction (XRD), Scanning Electron Microscopy (SEM) and transmission electron microscopy (TEM) were performed, and crystal structures of these samples were determined, while hexagonal superlattice without crystal order can be observed for S3 to exhibit crystal-like morphology.
Bright x-ray flares in gamma-ray burst afterglows.
Burrows, D N; Romano, P; Falcone, A; Kobayashi, S; Zhang, B; Moretti, A; O'brien, P T; Goad, M R; Campana, S; Page, K L; Angelini, L; Barthelmy, S; Beardmore, A P; Capalbi, M; Chincarini, G; Cummings, J; Cusumano, G; Fox, D; Giommi, P; Hill, J E; Kennea, J A; Krimm, H; Mangano, V; Marshall, F; Mészáros, P; Morris, D C; Nousek, J A; Osborne, J P; Pagani, C; Perri, M; Tagliaferri, G; Wells, A A; Woosley, S; Gehrels, N
2005-09-16
Gamma-ray burst (GRB) afterglows have provided important clues to the nature of these massive explosive events, providing direct information on the nearby environment and indirect information on the central engine that powers the burst. We report the discovery of two bright x-ray flares in GRB afterglows, including a giant flare comparable in total energy to the burst itself, each peaking minutes after the burst. These strong, rapid x-ray flares imply that the central engines of the bursts have long periods of activity, with strong internal shocks continuing for hundreds of seconds after the gamma-ray emission has ended.
2000-10-31
A repair crew works to repair the broken cleat on the crawler-transporter, found as it was moving up the incline on Launch Pad 39B. The Shuttle retreated to level ground so the broken cleat could be repaired. Endeavour is scheduled to be launched Nov. 30 at 10:01 p.m. EST on mission STS-97, the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections
2000-10-31
KENNEDY SPACE CENTER, Fla. -- Space Shuttle Endeavour is ready to move from the Vehicle Assembly Building into the light of early morning on its rollout to Launch Pad 39B. The Space Shuttle sits atop the Mobile Launcher Platform (MLP). Endeavour is scheduled to be launched Nov. 30 at 10:01 p.m. EST on mission STS-97, the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections
2000-10-31
KENNEDY SPACE CENTER, FLA. -- A repair crew works to remove a broken cleat (shoe) on the crawler-transporter moving the Space Shuttle Endeavour to Launch Pad 39B. The crack was noticed as the crawler-transporter started up the incline to the pad. Endeavour is scheduled to be launched Nov. 30 at 10:01 p.m. EST on mission STS-97, the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections
2000-10-31
KENNEDY SPACE CENTER, FLA. -- Workers stand by while the broken cleat (shoe) on the crawler-transporter is removed. The crack was noticed as the crawler-transporter, moving Space Shuttle Endeavour to Launch Pad 39B, started up the incline to the pad. Endeavour is scheduled to be launched Nov. 30 at 10:01 p.m. EST on mission STS-97, the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections
2000-10-31
KENNEDY SPACE CENTER, FLA. -- A worker adjusts equipment to remove a broken cleat (shoe) on the crawler-transporter moving the Space Shuttle Endeavour to Launch Pad 39B. The crack was noticed as the crawler-transporter started up the incline to the pad. Endeavour is scheduled to be launched Nov. 30 at 10:01 p.m. EST on mission STS-97, the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections
2000-10-31
KENNEDY SPACE CENTER, FLA. -- A repair crew works to remove a broken cleat (shoe) on the crawler-transporter moving the Space Shuttle Endeavour to Launch Pad 39B. The crack was noticed as the crawler-transporter started up the incline to the pad. Endeavour is scheduled to be launched Nov. 30 at 10:01 p.m. EST on mission STS-97, the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections
2000-10-31
KENNEDY SPACE CENTER, FLA. -- Workers stand by while the broken cleat (shoe) on the crawler-transporter is removed. The crack was noticed as the crawler-transporter, moving Space Shuttle Endeavour to Launch Pad 39B, started up the incline to the pad. Endeavour is scheduled to be launched Nov. 30 at 10:01 p.m. EST on mission STS-97, the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections
2000-10-31
KENNEDY SPACE CENTER, Fla. -- Space Shuttle Endeavour is ready to move from the Vehicle Assembly Building into the light of early morning on its rollout to Launch Pad 39B. The Space Shuttle sits atop the Mobile Launcher Platform (MLP). Endeavour is scheduled to be launched Nov. 30 at 10:01 p.m. EST on mission STS-97, the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections
2000-10-31
KENNEDY SPACE CENTER, FLA. -- A worker adjusts equipment to remove a broken cleat (shoe) on the crawler-transporter moving the Space Shuttle Endeavour to Launch Pad 39B. The crack was noticed as the crawler-transporter started up the incline to the pad. Endeavour is scheduled to be launched Nov. 30 at 10:01 p.m. EST on mission STS-97, the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections
Research of grasping algorithm based on scara industrial robot
NASA Astrophysics Data System (ADS)
Peng, Tao; Zuo, Ping; Yang, Hai
2018-04-01
As the tobacco industry grows, facing the challenge of the international tobacco giant, efficient logistics service is one of the key factors. How to complete the tobacco sorting task of efficient economy is the goal of tobacco sorting and optimization research. Now the cigarette distribution system uses a single line to carry out the single brand sorting task, this article adopts a single line to realize the cigarette sorting task of different brands. Using scara robot special algorithm for sorting and packaging, the optimization scheme significantly enhances the indicators of smoke sorting system. Saving labor productivity, obviously improve production efficiency.
A repair crew works on crawler-transporter
NASA Technical Reports Server (NTRS)
2000-01-01
A repair crew works to repair the broken cleat on the crawler- transporter, found as it was moving up the incline on Launch Pad 39B. The Shuttle retreated to level ground so the broken cleat could be repaired. Endeavour is scheduled to be launched Nov. 30 at 10:01 p.m. EST on mission STS-97, the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections.
STS-97 Mission Specialist Garneau with full launch and entry suit during pre-pack and fit check
NASA Technical Reports Server (NTRS)
2000-01-01
During pre-pack and fit check in the Operations and Checkout Building, STS-97 Commander Brent Jett gets help with his gloves from suit technician Bill Todd. Mission STS-97 is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST.
STS-97 Mission Specialist Garneau during pre-pack and fit check
NASA Technical Reports Server (NTRS)
2000-01-01
STS-97 Mission Specialist Marc Garneau gets help with his boots from suit technician Tommy McDonald during pre-pack and fit check. Garneau is with the Canadian Space Agency. Mission STS-97 is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST.
A Surprising Alliance: Two Giants of the 20th Century.
Sade, Robert M
2017-06-01
Alexis Carrel and Charles Lindbergh were among the most famous international figures in the 20th century: Carrel, the surgeon-scientist who won a Nobel prize as a young surgeon, and Lindbergh, the aviator-engineer who pioneered aviation and promoted commercial flight throughout his life. Surprisingly, these two amazing individuals came together to collaborate on the early development of extracorporeal circulation. Their work was interrupted by the onset of World War II, which destroyed one of them and nearly destroyed the other. Copyright © 2017 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
Infrared absorption cross sections of propane broadened by hydrogen
NASA Astrophysics Data System (ADS)
Wong, A.; Hargreaves, R. J.; Billinghurst, B.; Bernath, P. F.
2017-09-01
Fourier transform infrared absorption cross-sections of pure propane (C3H8) and propane broadened with H2 have been calculated from transmittance spectra recorded at temperatures from 292 K to 205 K. Transmittance spectra were recorded at the Canadian Light Source (CLS) Far-Infrared beamline, utilizing both the synchrotron source and the internal glowbar source. The absorption cross-sections have been calibrated to Pacific Northwest National Laboratory (PNNL) reference cross-sections of propane and can be used to interpret astronomical observations of giant planets such as Jupiter and Saturn as well as exoplanets.
Satellites of giant planets — possible sites for origin and existence of biospheres
NASA Astrophysics Data System (ADS)
Simakov, Michael B.
All giant planets of the Solar system have a big number of satellites (61 of Jupiter, 52 of Saturn, known in 2003). A small part of them consist very large bodies, quite comparable to planets of terrestrial type, but including very significant share of water ice. Some from them have an atmosphere. E.g., the mass of a column of the Titan’s atmosphere exceeds 15 times the mass of the Earth atmosphere column. Formation (or capture) of satellites is a natural phenomenon, and satellite systems definitely should exist at extrasolar planets. As an example, we can see on Titan, the largest satellite of Saturn, which has a dense nitrogen atmosphere and a large quantity of liquid water under ice cover and so has a great exobiological significance. The most recent models of the Titan’s interior lead to the conclusion that a substantial liquid layer exists today under relatively thin ice cover inside Titan. The putative internal water ocean along with complex atmospheric photochemistry provide some exobiological niches on this body: (1) an upper layer of the internal water ocean; (2) pores, veins, channels and pockets filled with brines inside of the lowest part of the icy layer; (3) the places of cryogenic volcanism; (4) set of caves in icy layer connecting with cryovolcanic processes; (5) the brine-filled cracks in icy crust caused by tidal forces; (6) liquid water pools on the surface originated from meteoritic strikes; (7) the sites of hydrothermal activity on the bottom of the ocean. We can see all conditions needed for origin and evolution of biosphere — liquid water, complex organic chemistry and energy sources for support of biological processes — are on the Saturnian moon. Galileo spacecraft has given indications, primarily from magnetometer and gravity data, of the possibility that three of Jupiter’s four large moons, Europa, Ganymede and Callisto have such oceans also. The existing of liquid water ocean within icy world can be consequences of the physical properties of water ice, and they neither require the addition of antifreeze substances nor any other special conditions. On Earth life exists in all niches where water exists in liquid form for at least a portion of the year. Possible metabolic processes, such as nitrate/nitrite reduction, sulfate reduction and methanogenesis could be suggested for internal oceans of Titan and Jovanian satellites. Excreted products of the primary chemoautotrophic organisms could serve as a source for other types of microorganisms (heterotrophes). Subglacial life may be widespread among such planetary bodies as satellites of extrasolar giant planets, detected in our Galaxy.
NASA Astrophysics Data System (ADS)
Fiorenza, Patrick; Nigro, Raffaella Lo; Raineri, Vito
Recently, giant dielectric permittivities (ɛ ' ˜ 104) have been found in several nonferroelectric materials such as CaCu3Ti4O12 (CCTO) (Subramanian et al., J. Solid State Chem. 151:323, 2000; Homes et al., Science 293:673, 2001), doped-NiO (Wu et al., Phys. Rev. Lett. 89:217601, 2002) systems (Li x Ti y Ni1 - x - y O, Li x Si y Ni1 - x - y O, Ki x Ti y Ni1 - x - y O), CuO, (Lin et al., Phys. Rev. B 72:014103, 2005; Sarkar et al., App. Phys. Lett. 92:142901, 2008) etc., and most important, the high ɛ ' values of these materials are almost independent over a wide range of temperature. This is one of the most intriguing features for their implementations in microelectronics devices, and as a consequence, these materials have been subjected to extensive research. Here, an introduction to such materials and to the methods for their dielectric characterization is given. So far, the crucial question is whether the large dielectric response is an intrinsic property of new class of crystals or an extrinsic property originated by a combination of the structural properties and other features such as defects and inhomogeneities. Preliminary, this peculiar dielectric behavior has been explained in powder ceramics by the internal barrier layer capacitor (IBLC) model, that is the presence of semiconducting domains surrounded by thin insulating regions within the crystal microstructure. It has been considered the most appropriate model and it has been generally accepted to explain the giant response of these materials. However, it could not be transferred to single crystals and thin films. In this scenario, scanning probe-based methods (like STM, KPFM, C-AFM, SIM etc) represent the most powerful instrument to understand the colossal permittivity-related physical phenomena, by investigations at nanoscale, clarifying the local effects responsible of the rising of macroscopic giant dielectric responses. Scanning probe microscopy investigations showed the relevance of inhomogeneity within single crystal, polycrystalline ceramics, and thin films. In particular, they are powerful tools to point out the presence of few nanometer wide internal barrier layers and of electrical domains, which are not recognisable with standard macroscopic electric characterization techniques.
Management of Giant Sequoia in the national forests of the Sierra Nevada, California
Robert R. Rogers
1986-01-01
The Forest Service avoided positive management activities within giant sequoia (Sequoiadendron giganteum [Lindl.] Buchholz) groves after heavy early logging on private lands caused adverse public reaction. However, since 1975 timber sales and prescribed burning have been conducted to encourage giant sequoia regeneration and increase tree vigor....
Potential of Myrothecium species as bioherbicides for giant salvinia (Salvinia molesta)
USDA-ARS?s Scientific Manuscript database
Giant salvinia is an exotic, invasive floating weed that can be difficult to manage. We examined a previously described isolate of the Myrothecium verrucaria and three new isolates of Myrotheicum roridum for virulence against giant salvinia. These plant pathogens were grown on a standard medium, p...
78 FR 20792 - Safety Zone; San Francisco Giants Fireworks Display, San Francisco, CA
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-08
... Zone; San Francisco Giants Fireworks Display, San Francisco, CA AGENCY: Coast Guard, DHS. ACTION... Francisco Giants Fireworks Display in the Captain of the Port, San Francisco area of responsibility during... public from the hazards associated with the fireworks display. During the enforcement period...
77 FR 28771 - Safety Zone; San Francisco Giants Fireworks Display, San Francisco, CA
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-16
... Zone; San Francisco Giants Fireworks Display, San Francisco, CA AGENCY: Coast Guard, DHS. ACTION... Francisco Giants Fireworks Display in the Captain of the Port, San Francisco area of responsibility during... public from the hazards associated with the fireworks display. During the enforcement period...
Wood of Giant Sequoia: properties and unique characteristics
Douglas D. Piirto
1986-01-01
Wood properties of giant sequoia (Sequoia gigantea [Lindl.] Decne.) were compared with those for other coniferous tree species. Wood properties such as specific gravity, various mechanical properties, extractive content, and decay resistance of young-growth giant sequoia are comparable to or more favorable than those of coast redwood (...
Evolution and history of Giant Sequoia
H. Thomas Harvey
1986-01-01
Ancient ancestors of the giant sequoia (Sequoiadendron giganteum [Lindl.] Buchholz) were widespread throughout much of the Northern Hemisphere during the late Mesozoic Period. Climatic conditions changed, forcing the more recent ancestors of present giant sequoia into the southwestern United States. The native range is now restricted to the west slope of the Sierra...
The early evolution of giant H II regions formed by supernova explosions
NASA Technical Reports Server (NTRS)
Kafatos, M. C.
1971-01-01
The evolution of a giant H II region, which cools after an initial ionization, is discussed. The discussion is applied to the Vela X and Tycho supernovae. Other giant H II regions might not be as easily detectable as the Vela X region. The Tycho region may be just detectable in the O(II) or O(III) optical lines or as a hole in the 21-cm emission line profiles, as is suggested in the data. These giant H II regions last appreciably longer than the continuum radio sources within them.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Muñoz-Gutiérrez, M. A.; Pichardo, B.; Peimbert, A., E-mail: mmunoz.astro@gmail.com
We have explored the evolution of a cold debris disk under the gravitational influence of dwarf-planet-sized objects (DPs), both in the presence and absence of an interior giant planet. Through detailed long-term numerical simulations, we demonstrate that when the giant planet is not present, DPs can stir the eccentricities and inclinations of disk particles, in linear proportion to the total mass of the DPs; on the other hand, when the giant planet is included in the simulations, the stirring is approximately proportional to the mass squared. This creates two regimes: below a disk mass threshold (defined by the total massmore » of DPs), the giant planet acts as a stabilizing agent of the orbits of cometary nuclei, diminishing the effect of the scatterers; above the threshold, the giant contributes to the dispersion of the particles.« less
Chromospheric activity of cool giant stars
NASA Technical Reports Server (NTRS)
Steiman-Cameron, T. Y.
1986-01-01
During the seventh year of IUE twenty-six spectra of seventeen cool giant stars ranging in spectral type from K3 thru M6 were obtained. Together with spectra of fifteen stars observed during the sixth year of IUE, these low-resolution spectra have been used to: (1) examine chromospheric activity in the program stars and late type giants in general, and (2) evaluate the extent to which nonradiative heating affects the upper levels of cool giant photospheres. The stars observed in this study all have well determined TiO band strengths, angular diameters (determined from lunar occulations), bolometric fluxes, and effective temperatures. Chromospheric activity can therefore be related to effective temperatures providing a clearer picture of activity among cool giant stars than previously available. The stars observed are listed.
Lithium Abundance in M3 Red Giant
NASA Astrophysics Data System (ADS)
Givens, Rashad; Pilachowski, Catherine A.
2015-01-01
We present the abundance of lithium in the red giant star vZ 1050 (SK 291) in the globular cluster M3. A previous survey of giants in the cluster showed that like IV-101, vZ 1050 displays a prominent Li I 6707 Å feature. vZ 1050 lies on the blue side of the red giant branch about 1.3 magnitudes above the level of the horizontal branch, and may be an asymptotic giant branch star. A high resolution spectrum of M3 vZ1050 was obtained with the ARC 3.5m telescope and the ARC Echelle Spectrograph (ARCES). Atmospheric parameters were determined using Fe I and Fe II lines from the spectrum using the MOOG spectral analysis program, and the lithium abundance was determined using spectrum synthesis.
Giant Cell Arteritis Presenting as Scalp Necrosis
Maidana, Daniel E.; Muñoz, Silvia; Acebes, Xènia; Llatjós, Roger; Jucglà, Anna; Álvarez, Alba
2011-01-01
The differential of scalp ulceration in older patients should include several causes, such as herpes zoster, irritant contact dermatitis, ulcerated skin tumors, postirradiation ulcers, microbial infections, pyoderma gangrenosum, and giant cell arteritis. Scalp necrosis associated with giant cell arteritis was first described in the 1940s. The presence of this dermatological sign within giant cell arteritis represents a severity marker of this disease, with a higher mean age at diagnosis, an elevated risk of vision loss and tongue gangrene, as well as overall higher mortality rates, in comparison to patients not presenting this manifestation. Even though scalp necrosis due to giant cell arteritis is exceptional, a high level of suspicion must be held for this clinical finding, in order to initiate prompt and proper treatment and avoid blindness. PMID:21789466
A DEFINITION FOR GIANT PLANETS BASED ON THE MASS–DENSITY RELATIONSHIP
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hatzes, Artie P.; Rauer, Heike, E-mail: artie@tls-tautenburg.de, E-mail: Heike.Rauer@dlr.de
We present the mass–density relationship (log M − log ρ) for objects with masses ranging from planets (M ≈ 0.01 M{sub Jup}) to stars (M > 0.08 M{sub ⊙}). This relationship shows three distinct regions separated by a change in slope in the log M − log ρ plane. In particular, objects with masses in the range 0.3 M{sub Jup}–60 M{sub Jup} follow a tight linear relationship with no distinguishing feature to separate the low-mass end (giant planets) from the high-mass end (brown dwarfs). We propose a new definition of giant planets simply based on changes in the slope ofmore » the log M versus log ρ relationship. By this criterion, objects with masses less than ≈0.3 M{sub Jup} are low-mass planets, either icy or rocky. Giant planets cover the mass range 0.3 M{sub Jup}–60 M{sub Jup}. Analogous to the stellar main sequence, objects on the upper end of the giant planet sequence (brown dwarfs) can simply be referred to as “high-mass giant planets,” while planets with masses near that of Jupiter can be called “low-mass giant planets.”.« less
NASA Astrophysics Data System (ADS)
Raymond, Sean; Mandell, A.; Sigurdsson, S.
2006-12-01
Gas giant planets are far easier than terrestrial planets to detect around other stars, and are thought to form much more quickly than terrestrial planets. Thus, in systems with giant planets, the final stages of terrestrial planet formation are strongly affected by the giant planets' dynamical presence. Observations of giant planet orbits may therefore constrain the systems that can harbor potentially habitable, Earth-like planets. We combine two recent studies (1,2) and establish rough inner and outer limits for the giant planet orbits that allow terrestrial planets of at least 0.3 Earth masses to form in the habitable zone (HZ). For a star like the Sun, potentially habitable planets can form in systems with relatively low-eccentricity giant planets inside 0.5 Astronomical Units (AU) or outside 2.5 AU. More than one third of the currently known giant planet systems could have formed and now harbor a habitable planet. We thank NASA Astrobiology Institute for funding, through the Penn State, NASA Goddard, Virtual Planetary Laboratory, and University of Colorado lead teams. (1. Raymond, S.N., 2006, ApJ, 643, L131.; 2. Raymond, S.N., Mandell, A.M., Sigurdsson, S. 2006, Science, 313, 1413).
Photoevaporation Does Not Create a Pileup of Giant Planets at 1 au
NASA Astrophysics Data System (ADS)
Wise, A. W.; Dodson-Robinson, S. E.
2018-03-01
The semimajor axis distribution of giant exoplanets appears to have a pileup near 1 au. Photoevaporation opens a gap in the inner few au of gaseous disks before dissipating them. Here, we investigate if photoevaporation can significantly affect the final distribution of giant planets by modifying gas surface density and hence Type II migration rates near the photoevaporation gap. We first use an analytic disk model to demonstrate that newly formed giant planets have a long migration epoch before photoevaporation can significantly alter their migration rates. Next, we present new 2D hydrodynamic simulations of planets migrating in photoevaporating disks, in which each are paired with a control simulation of migration in an otherwise identical disk without photoevaporation. We show that in disks with surface densities near the minimum threshold for forming giant planets, photoevaporation alters the final semimajor axis of a migrating gas giant by at most 5% over the course of 0.1 Myr of migration. Once the disk mass has become low enough for photoevaporation to carve a sharp gap, migration has almost completely stalled due to the low surface density of gas at the Lindblad resonances. We find that photoevaporation modifies migration rates so little that it is unlikely to leave a significant signature on the distribution of giant exoplanets.
Zheng, Yang; Cai, Jing; Li, JianWen; Li, Bo; Lin, Runmao; Tian, Feng; Wang, XiaoLing; Wang, Jun
2010-01-01
A 10-fold BAC library for giant panda was constructed and nine BACs were selected to generate finish sequences. These BACs could be used as a validation resource for the de novo assembly accuracy of the whole genome shotgun sequencing reads of giant panda newly generated by the Illumina GA sequencing technology. Complete sanger sequencing, assembly, annotation and comparative analysis were carried out on the selected BACs of a joint length 878 kb. Homologue search and de novo prediction methods were used to annotate genes and repeats. Twelve protein coding genes were predicted, seven of which could be functionally annotated. The seven genes have an average gene size of about 41 kb, an average coding size of about 1.2 kb and an average exon number of 6 per gene. Besides, seven tRNA genes were found. About 27 percent of the BAC sequence is composed of repeats. A phylogenetic tree was constructed using neighbor-join algorithm across five species, including giant panda, human, dog, cat and mouse, which reconfirms dog as the most related species to giant panda. Our results provide detailed sequence and structure information for new genes and repeats of giant panda, which will be helpful for further studies on the giant panda.
Hu, Yao-Dong; Pang, Hui-Zhong; Li, De-Sheng; Ling, Shan-Shan; Lan, Dan; Wang, Ye; Zhu, Yun; Li, Di-Yan; Wei, Rong-Ping; Zhang, He-Min; Wang, Cheng-Dong
2016-11-05
As the rate-limiting enzyme of the mitochondrial respiratory chain, cytochrome c oxidase (COX) plays a crucial role in biological metabolism. "Living fossil" giant panda (Ailuropoda melanoleuca) is well-known for its special bamboo diet. In an effort to explore functional variation of COX1 in the energy metabolism behind giant panda's low-energy bamboo diet, we looked at genetic variation of COX1 gene in giant panda, and tested for its selection effect. In 1545 base pairs of the gene from 15 samples, 9 positions were variable and 1 mutation leaded to an amino acid sequence change. COX1 gene produces six haplotypes, nucleotide (pi), haplotype diversity (Hd). In addition, the average number of nucleotide differences (k) is 0.001629±0.001036, 0.8083±0.0694 and 2.517, respectively. Also, dN/dS ratio is significantly below 1. These results indicated that giant panda had a low population genetic diversity, and an obvious purifying selection of the COX1 gene which reduces synthesis of ATP determines giant panda's low-energy bamboo diet. Phylogenetic trees based on the COX1 gene were constructed to demonstrate that giant panda is the sister group of other Ursidae. Copyright © 2016 Elsevier B.V. All rights reserved.
A novel polyomavirus from the nasal cavity of a giant panda (Ailuropoda melanoleuca).
Qi, Dunwu; Shan, Tongling; Liu, Zhijian; Deng, Xutao; Zhang, Zhihe; Bi, Wenlei; Owens, Jacob Robert; Feng, Feifei; Zheng, Lisong; Huang, Feng; Delwart, Eric; Hou, Rong; Zhang, Wen
2017-10-27
Polyomaviruses infect a wide variety of mammalian and avian hosts with a broad spectrum of outcomes including asymptomatic infection, acute systemic disease, and tumor induction. Viral metagenomics and general PCR methods were used to detected viral nucleic acid in the samples from a diseased and healthy giant pandas. A novel polyomavirus, the giant panda polyomavirus 1 (GPPyV1) from the nasal cavity of a dead giant panda (Ailuropoda melanoleuca) was characterized. The GPPyV1 genome is 5144 bp in size and reveals five putative open-reading frames coding for the classic small and large T antigens in the early region, and the VP1, VP2 and VP3 capsid proteins in the late region. Phylogenetic analyses of the large T antigen of the GPPyV1 indicated GPPyV1 belonged to a putative new species within genus Deltapolyomavirus, clustering with four human polyomavirus species. The GPPyV1 VP1 and VP2 clustered with genus Alphapolyomavirus. Our epidemiologic study indicated that this novel polyomavirus was also detected in nasal swabs and fecal samples collected from captive healthy giant pandas. A novel polyomavirus was detected in giant pandas and its complete genome was characterized, which may cause latency infection in giant pandas.
Borgen, Melissa; Rowland, Kimberly; Boerner, Jana; Lloyd, Brandon; Khan, Aruna; Murphey, Rodney
2017-03-01
The ubiquitin ligase Highwire has a conserved role in synapse formation. Here, we show that Highwire coordinates several facets of central synapse formation in the Drosophila melanogaster giant fiber system, including axon termination, axon pruning, and synaptic function. Despite the similarities to the fly neuromuscular junction, the role of Highwire and the underlying signaling pathways are distinct in the fly's giant fiber system. During development, branching of the giant fiber presynaptic terminal occurs and, normally, the transient branches are pruned away. However, in highwire mutants these ectopic branches persist, indicating that Highwire promotes axon pruning. highwire mutants also exhibit defects in synaptic function. Highwire promotes axon pruning and synaptic function cell-autonomously by attenuating a mitogen-activated protein kinase pathway including Wallenda, c-Jun N-terminal kinase/Basket, and the transcription factor Jun. We also show a novel role for Highwire in non-cell autonomous promotion of synaptic function from the midline glia. Highwire also regulates axon termination in the giant fibers, as highwire mutant axons exhibit severe overgrowth beyond the pruning defect. This excessive axon growth is increased by manipulating Fos expression in the cells surrounding the giant fiber terminal, suggesting that Fos regulates a trans -synaptic signal that promotes giant fiber axon growth. Copyright © 2017 by the Genetics Society of America.
Spectral Flattening at Low Frequencies in Crab Giant Pulses
NASA Astrophysics Data System (ADS)
Meyers, B. W.; Tremblay, S. E.; Bhat, N. D. R.; Shannon, R. M.; Kirsten, F.; Sokolowski, M.; Tingay, S. J.; Oronsaye, S. I.; Ord, S. M.
2017-12-01
We report on simultaneous wideband observations of Crab giant pulses with the Parkes radio telescope and the Murchison Widefield Array (MWA). The observations were conducted simultaneously at 732 and 3100 MHz with Parkes and at 120.96, 165.76, and 210.56 MHz with the MWA. Flux density calibration of the MWA data was accomplished using a novel technique based on tied-array beam simulations. We detected between 90 and 648 giant pulses in the 120.96-210.56 MHz MWA subbands above a 5.5σ threshold, while in the Parkes subbands we detected 6344 and 231 giant pulses above a threshold of 6σ at 732 and 3100 MHz, respectively. We show, for the first time over a wide frequency range, that the average spectrum of Crab giant pulses exhibits a significant flattening at low frequencies. The spectral index, α, for giant pulses evolves from a steep, narrow distribution with a mean α =-2.6 and width {σ }α =0.5 between 732 and 3100 MHz to a wide, flat distribution of spectral indices with a mean α =-0.7 and width {σ }α =1.4 between 120.96 and 165.76 MHz. We also comment on the plausibility of giant pulse models for fast radio bursts based on this spectral information.
NASA Astrophysics Data System (ADS)
Takeda, Yoichi; Tajitsu, Akito
2017-08-01
While lithium is generally deficient in the atmosphere of evolved giant stars because of the efficient mixing-induced dilution, a small fraction of red giants show unusually strong Li lines indicative of conspicuous abundance excess. With the aim of shedding light on the origin of these peculiar stars, we carried out a spectroscopic study on the observational characteristics of 20 selected bright giants already known to be Li-rich from past studies, in comparison with the reference sample of a large number of normal late G-early K giants. Special attention was paid to clarifying any difference between the two samples from a comprehensive point of view (i.e., with respect to stellar parameters, rotation, activity, kinematic properties, 6Li/7Li ratio, and the abundances of Li, Be, C, O, Na, S, and Zn). Our sample stars are roughly divided into a “bump/clump group” and a “luminous group” according to their positions on the HR diagram. Regarding the former group [1.5 ≲ log (L/L⊙) ≲ 2 and M ∼ 1.5-3 M⊙], Li-enriched giants and normal giants appear practically similar in almost all respects except for Li, suggesting that surface Li enhancement in this group may be a transient episode which normal giants undergo at certain evolutionary stages in their lifetime. Meanwhile, those Li-rich giants belonging to the latter group [log (L/L⊙) ∼ 3 and M ∼ 3-5 M⊙] appear more anomalous in the sense that they tend to show higher rotation as well as higher activity, and that their elemental abundances (especially those derived from high-excitation lines) are apt to show apparent overabundances, though this might be due to a spurious effect reflecting the difficulty of abundance derivation in stars of higher rotation and activity. Our analysis confirmed considerable Be deficiency as well as absence of 6Li as the general characteristics of Li-rich giants under study, which implies that engulfment of planets is rather unlikely for the origin of Li-enrichment.
High surface magnetic field in red giants as a new signature of planet engulfment?
NASA Astrophysics Data System (ADS)
Privitera, Giovanni; Meynet, Georges; Eggenberger, Patrick; Georgy, Cyril; Ekström, Sylvia; Vidotto, Aline A.; Bianda, Michele; Villaver, Eva; ud-Doula, Asif
2016-09-01
Context. Red giant stars may engulf planets. This may increase the rotation rate of their convective envelope, which could lead to strong dynamo-triggered magnetic fields. Aims: We explore the possibility of generating magnetic fields in red giants that have gone through the process of a planet engulfment. We compare them with similar models that evolve without any planets. We discuss the impact of magnetic braking through stellar wind on the evolution of the surface velocity of the parent star. Methods: By studying rotating stellar models with and without planets and an empirical relation between the Rossby number and the surface magnetic field, we deduced the evolution of the surface magnetic field along the red giant branch. The effects of stellar wind magnetic braking were explored using a relation deduced from magnetohydrodynamics simulations. Results: The stellar evolution model of a red giant with 1.7 M⊙ without planet engulfment and with a time-averaged rotation velocity during the main sequence equal to 100 km s-1 shows a surface magnetic field triggered by convection that is stronger than 10 G only at the base of the red giant branch, that is, for gravities log g> 3. When a planet engulfment occurs, this magnetic field can also appear at much lower gravities, that is, at much higher luminosities along the red giant branch. The engulfment of a 15 MJ planet typically produces a dynamo-triggered magnetic field stronger than 10 G for gravities between 2.5 and 1.9. We show that for reasonable magnetic braking laws for the wind, the high surface velocity reached after a planet engulfment may be maintained sufficiently long to be observable. Conclusions: High surface magnetic fields for red giants in the upper part of the red giant branch are a strong indication of a planet engulfment or of an interaction with a companion. Our theory can be tested by observing fast-rotating red giants such as HD 31994, Tyc 0347-00762-1, Tyc 5904-00513-1, and Tyc 6054-01204-1 and by determining whether they show magnetic fields.
Zenone, Thierry; Puget, Marie
2013-12-01
The objective of this study was to determine the characteristics of cerebrovascular accidents at time of diagnosis in patients with giant cell arteritis. Retrospective data were collected from 98 patients at a single hospital with giant cell arteritis (according to the American College of Rheumatology classification criteria) diagnosed between October 1999 and January 2012. Cerebrovascular accident was found at initial presentation in 6 patients (6.1 %, 95 % CIs 2.3-12.9). Most of them had other symptoms of giant cell arteritis when the disease began. Signs reflecting the involvement of vertebro-basilar territory were present in 3 cases. No other case of cerebrovascular accident was described during the follow-up of patient; particularly no case of cerebrovascular accident occurred once corticosteroid therapy for the treatment of giant cell arteritis had been initiated. No differences in the epidemiologic, clinical and laboratory features at the time of diagnosis between patients who had cerebrovascular accidents and the rest of the giant cell arteritis patients were observed. Prognosis was good in our survey. However, there was no case of bilateral vertebral artery occlusion, a condition associated with poor prognosis. The present study confirms that cerebrovascular accidents may be the initial manifestation of giant cell arteritis, an argument in favor of a direct effect of the vasculitis in the development of cerebrovascular accidents rather than a complication of the corticosteroid therapy. The diagnosis of giant cell arteritis should always be considered in an elderly patient with stroke and an unexplained elevation of inflammatory biomarkers.
The Vocal Repertoire of Adult and Neonate Giant Otters (Pteronura brasiliensis)
Mumm, Christina A. S.; Knörnschild, Mirjam
2014-01-01
Animals use vocalizations to exchange information about external events, their own physical or motivational state, or about individuality and social affiliation. Infant babbling can enhance the development of the full adult vocal repertoire by providing ample opportunity for practice. Giant otters are very social and frequently vocalizing animals. They live in highly cohesive groups, generally including a reproductive pair and their offspring born in different years. This basic social structure may vary in the degree of relatedness of the group members. Individuals engage in shared group activities and different social roles and thus, the social organization of giant otters provides a basis for complex and long-term individual relationships. We recorded and analysed the vocalizations of adult and neonate giant otters from wild and captive groups. We classified the adult vocalizations according to their acoustic structure, and described their main behavioural context. Additionally, we present the first description of vocalizations uttered in babbling bouts of new born giant otters. We expected to find 1) a sophisticated vocal repertoire that would reflect the species’ complex social organisation, 2) that giant otter vocalizations have a clear relationship between signal structure and function, and 3) that the vocal repertoire of new born giant otters would comprise age-specific vocalizations as well as precursors of the adult repertoire. We found a vocal repertoire with 22 distinct vocalization types produced by adults and 11 vocalization types within the babbling bouts of the neonates. A comparison within the otter subfamily suggests a relation between vocal and social complexity, with the giant otters being the socially and vocally most complex species. PMID:25391142
Lorenz, Jonas; Kubesch, Alica; Korzinskas, Tadas; Barbeck, Mike; Landes, Constantin; Sader, Robert A; Kirkpatrick, Charles J; Ghanaati, Shahram
2015-12-01
This study compared the material-specific tissue response to the synthetic, hydroxyapatite-based bone substitute material NanoBone (NB) with that of the xenogeneic, bovine-based bone substitute material Bio-Oss (BO). The sinus cavities of 14 human patients were augmented with NB and BO in a split-mouth design. Six months after augmentation, bone biopsies were extracted for histological and histomorphometric investigation prior to dental implant insertion. The following were evaluated: the cellular inflammatory pattern, the induction of multinucleated giant cells, vascularization, the relative amounts of newly formed bone, connective tissue, and the remaining bone substitute material. NB granules were well integrated in the peri-implant tissue and were surrounded by newly formed bone tissue. Multinucleated giant cells were visible on the surfaces of the remaining granules. BO granules were integrated into the newly formed bone tissue, which originated from active osteoblasts on their surface. Histomorphometric analysis showed a significantly higher number of multinucleated giant cells and blood vessels in the NB group compared to the BO group. No statistical differences were observed in regard to connective tissue, remaining bone substitute, and newly formed bone. The results of this study highlight the different cellular reactions to synthetic and xenogeneic bone substitute materials. The significantly higher number of multinucleated giant cells within the NB implantation bed seems to have no effect on its biodegradation. Accordingly, the multinucleated giant cells observed within the NB implantation bed have characteristics more similar to those of foreign body giant cells than to those of osteoclasts.
Genetic variation and early performance of Giant Sequoia in plantations
W. J. Libby
1986-01-01
Giant sequoia (Sequoiadendron giganteum [Lindl.] Buchholz) is genetically less variable than expected; furthermore, it is less variable and its populations are less structured than are several associated or related conifers. Giant sequoia seedlings from open-pollinated seeds of isolated trees or from small outlier groves do not survive and grow as...
USDA-ARS?s Scientific Manuscript database
The armored arundo scale, Rhizaspidiotus donacis (Homoptera: Diaspididae) has been permitted for a biological control agent to control invasive populations of giant reed (Arundo donax L.). A non-native, highly invasive woody grass, giant reed infests waterways and riparian areas of the southwestern...
Giant calculus: review and report of a case.
Woodmansey, Karl; Severine, Anthony; Lembariti, Bakari S
2013-01-01
Dental calculus is a common oral finding. The term giant calculus is used to describe unusually large deposits of dental calculus. Several extreme cases have been reported in the dental literature. The specific etiology of these cases remains uncertain. This paper reviews previously reported cases, and presents another extreme example of giant calculus.
USDA-ARS?s Scientific Manuscript database
Giant ragweed has been increasing as a major weed of row crops in North America. We conducted a web-based survey of Certified Crop Advisors in the Corn Belt to determine the current distribution of giant ragweed, the distribution of herbicide resistant populations, and management and ecological fact...
Properties of the O-type giants and supergiants in 30 Doradus
NASA Astrophysics Data System (ADS)
Ramírez-Agudelo, O. H.; VFTS Consortium
2017-11-01
We discuss the stellar and wind properties of 72 presumably single O-type giants, bright giants, and supergiants in the 30 Doradus region. This sample constitutes the largest and most homogeneous sample of such stars ever analyzed and offers the opportunity to test models describing their main-sequence evolution.
Forming giant-sized polymersomes using gel-assisted rehydration
Greene, Adrienne C.; Sasaki, Darryl Y.; Bachand, George D.
2016-05-26
Here, we present a protocol to rapidly form giant polymer vesicles ( pGVs). Briefly, polymer solutions are dehydrated on dried agarose films adhered to coverslips. Rehydration of the polymer films results in rapid formation of pGVs. This method greatly advances the preparation of synthetic giant vesicles for direct applications in biomimetic studies.
Serosurvey of selected viruses in captive giant pandas (Ailuropoda melanoleuca) in China.
Qin, Qin; Li, Desheng; Zhang, Hemin; Hou, Rong; Zhang, Zhihe; Zhang, Chenglin; Zhang, Jinguo; Wei, Fuwen
2010-05-19
Serum samples from 92 giant pandas in three captive facilities were tested for antibodies against five viruses of carnivores. Antibody titers against canine distemper virus (CDV) in two facilities in which giant pandas were vaccinated were variable. The canine adenovirus (CAV-1) and canine parvovirus (CPV) titers in vaccinated group were both positive, but titers were not high and varied among individual except one vaccinated panda had extremely high CAV-1 titer, indicating infection with the field virus following vaccination. Our results suggest that the vaccines used for these giant pandas do not elicit consistent antibody titers. Antibody titers against CDV, CPV and CAV-1 in unvaccinated giant pandas were highly variable, especially CPV titer. Almost half of sera were CPV antibody positive, and CPV titers were high enough to suggest infection with the virus. Canine coronavirus (CCV) and canine parainfluenza virus (CPIV) titers were not detected in all serum samples. The results of this study emphasize the need for research on infectious diseases of giant pandas and development of suitable vaccines for the species. Copyright 2009 Elsevier B.V. All rights reserved.
Female giant panda (Ailuropoda melanoleuca) chirps advertise the caller's fertile phase
Charlton, Benjamin D.; Keating, Jennifer L.; Rengui, Li; Huang, Yan; Swaisgood, Ronald R.
2010-01-01
Although female mammal vocal behaviour is known to advertise fertility, to date, no non-human mammal study has shown that the acoustic structure of female calls varies significantly around their fertile period. Here, we used a combination of hormone measurements and acoustic analyses to determine whether female giant panda chirps have the potential to signal the caller's precise oestrous stage (fertile versus pre-fertile). We then used playback experiments to examine the response of male giant pandas to female chirps produced during fertile versus pre-fertile phases of the caller's reproductive cycle. Our results show that the acoustic structure of female giant panda chirps differs between fertile and pre-fertile callers and that male giant pandas can perceive differences in female chirps that allow them to determine the exact timing of the female's fertile phase. These findings indicate that male giant pandas could use vocal cues to preferentially associate and copulate with females at the optimum time for insemination and reveal the likely importance of female vocal signals for coordinating reproductive efforts in this critically endangered species. PMID:19955154
A genome-wide survey on basic helix-loop-helix transcription factors in giant panda.
Dang, Chunwang; Wang, Yong; Zhang, Debao; Yao, Qin; Chen, Keping
2011-01-01
The giant panda (Ailuropoda melanoleuca) is a critically endangered mammalian species. Studies on functions of regulatory proteins involved in developmental processes would facilitate understanding of specific behavior in giant panda. The basic helix-loop-helix (bHLH) proteins play essential roles in a wide range of developmental processes in higher organisms. bHLH family members have been identified in over 20 organisms, including fruit fly, zebrafish, mouse and human. Our present study identified 107 bHLH family members being encoded in giant panda genome. Phylogenetic analyses revealed that they belong to 44 bHLH families with 46, 25, 15, 4, 11 and 3 members in group A, B, C, D, E and F, respectively, while the remaining 3 members were assigned into "orphan". Compared to mouse, the giant panda does not encode seven bHLH proteins namely Beta3a, Mesp2, Sclerax, S-Myc, Hes5 (or Hes6), EBF4 and Orphan 1. These results provide useful background information for future studies on structure and function of bHLH proteins in the regulation of giant panda development.
Quantifying landscape linkages among giant panda subpopulations in regional scale conservation.
Qi, Dunwu; Hu, Yibo; Gu, Xiaodong; Yang, Xuyi; Yang, Guang; Wei, Fuwen
2012-06-01
Understanding habitat requirements and identifying landscape linkages are essential for the survival of isolated populations of endangered species. Currently, some of the giant panda populations are isolated, which threatens their long-term survival, particularly in the Xiaoxiangling mountains. In the present study, we quantified niche requirements and then identified potential linkages of giant panda subpopulations in the most isolated region, using ecological niche factor analysis and a least-cost path model. Giant pandas preferred habitat with conifer forest and gentle slopes (>20 to ≤30°). Based on spatial distribution of suitable habitat, linkages were identified for the Yele subpopulation to 4 other subpopulations (Liziping, Matou, Xinmin and Wanba). Their lengths ranged from 15 to 54 km. The accumulated cost ranged from 693 to 3166 and conifer forest covered over 31%. However, a variety of features (e.g. major roads, human settlements and large unforested areas) might act as barriers along the linkages for giant panda dispersal. Our analysis quantified giant panda subpopulation connectivity to ensure long-term survival. © 2012 ISZS, Blackwell Publishing and IOZ/CAS.
Nakayama, Shingo; Sasaki, Mamoru; Morinaga, Shojiroh
2018-01-01
Giant cell carcinoma, a rare variant of nonsmall cell lung carcinoma (NSCLC), is characterized by aggressive progression and poor response to conventional chemotherapy. This report is the first to describe a patient with NSCLC and giant cell features who was successfully treated with pembrolizumab, an antibody targeting programmed death-1 (PD-1). A 69-year-old woman was diagnosed with NSCLC with multiple brain metastases. Histological evaluation of lung biopsy specimens revealed proliferation of pleomorphic giant tumor cells with poor cohesiveness, findings consistent with giant cell carcinoma. Immunostaining showed that a high proportion of the tumor cells were positive for expression of programmed death-ligand 1 (PD-L1). The patient received stereotactic radiotherapy for the brain metastases, followed by administration of pembrolizumab. Treatment with pembrolizumab resulted in the rapid regression of the primary lung nodule, with the progression-free period maintained for at least four treatment cycles. Immunotherapy targeting PD-1/PD-L1 may be an option for patients with PD-L1-positive NSCLC with giant cell features. PMID:29736285
Nakayama, Shingo; Sasaki, Mamoru; Morinaga, Shojiroh; Minematsu, Naoto
2018-01-01
Giant cell carcinoma, a rare variant of nonsmall cell lung carcinoma (NSCLC), is characterized by aggressive progression and poor response to conventional chemotherapy. This report is the first to describe a patient with NSCLC and giant cell features who was successfully treated with pembrolizumab, an antibody targeting programmed death-1 (PD-1). A 69-year-old woman was diagnosed with NSCLC with multiple brain metastases. Histological evaluation of lung biopsy specimens revealed proliferation of pleomorphic giant tumor cells with poor cohesiveness, findings consistent with giant cell carcinoma. Immunostaining showed that a high proportion of the tumor cells were positive for expression of programmed death-ligand 1 (PD-L1). The patient received stereotactic radiotherapy for the brain metastases, followed by administration of pembrolizumab. Treatment with pembrolizumab resulted in the rapid regression of the primary lung nodule, with the progression-free period maintained for at least four treatment cycles. Immunotherapy targeting PD-1/PD-L1 may be an option for patients with PD-L1-positive NSCLC with giant cell features.
Guziński, Maciej; Kurcz, Jacek; Kukulska, Monika; Neska, Małgorzata; Garcarek, Jerzy
2015-01-01
Although splenic artery aneurysms (SAAs) are common, their giant forms (more than 10 cm in diameter) are rare. Because of the variety of forms and locations of these aneurysms, there are a lot of therapeutic methods to choose. In our case of a giant true aneurysm we performed an endovascular embolization with N-butyl-cyano-acrylate (NBCA) glue. To our knowledge it is the first reported case of this method of treatment of true giant SAA. A 74-year-old male patient with symptomatic giant SAA (13 cm) was urgently admitted to our hospital for the diagnostic and therapeutic procedures. Due to the general health condition, advanced age and the large size of the aneurysm we decided to perform an endovascular treatment with N-butyl-cyano-acrylate (NBCA) glue. The preaneurysmal part of splenic artery was occluded completely with exclusion of the aneurysm. No splenectomy was needed. The patient was discharged in good general condition Embolization with NBCA can be an efficient method to treat the giant SAA.
Some Observations on the Fine Structure of the Giant Nerve Fibers of the Earthworm, Eisenia foetida
Hama, Kiyoshi
1959-01-01
Sectioned dorsal giant fibers of the earthworm Eisenia foetida have been studied with the electron microscope. The giant axon is surrounded by a Schwannian sheath in which the lamellae are arranged spirally. They can be traced from the outer surface of the Schwann cell to the axon-Schwann membranes. Irregularities in the spiral arrangement are frequently observed. Desmosome-like attachment areas occur on the giant fiber nerve sheath. These structures appear to be arranged bilaterally in columns which are oriented slightly obliquely to the long axis of the giant fiber and aligned linearly from the axon to the periphery of the sheath. At these sites they bind together apposing portions of Schwann cell membrane comprising the sheath. Longitudinal or oblique sections of the nerve sheath attachment areas are reminiscent of the Schmidt-Lantermann clefts of vertebrate peripheral nerve. Septa of the giant fibers have been examined. They are symmetrical or non-polarized and consist of the two plasma membranes of adjacent nerve units. Characteristic vesicular and tubular structures are associated with both cytoplasmic surfaces of these septa. PMID:13673048
Genetic Interaction of Neuroglian and Semaphorin1a during Guidance and Synapse Formation
Godenschwege, Tanja A.; Murphey, Rodney K.
2009-01-01
We have previously demonstrated a function for Neuroglian and Semaphorin1a in Drosophila giant fiber circuit formation. Both molecules are required for guiding the giant fibers out of the brain and have distinct functions during giant synapse formation. In this study we characterized the effects of various combinations of Neuroglian and Semaphorin1a gain and loss of function backgrounds on giant fiber circuitry formation. We found that Neuroglian and Semaphorin1a genetically interact with each other during axon guidance as well as during synapse formation. Our experiments revealed that during pathfinding of the giant fibers out of the brain, Neuroglian function seems to be dependent on Semaphorin1a. In contrast, during giant fiber synapse formation we observed that Semaphorin1a signaling as a receptor can be altered by Neuroglian in the same cell. In summary, our findings suggest that Neuroglian and Semaphorin1a can regulate each other’s function in cis and that the resultant signaling output is possibly different during guidance and synapse formation. PMID:19052954
Theories of the origin and evolution of the giant planets
NASA Technical Reports Server (NTRS)
Pollack, J. B.; Bodenheimer, P.
1989-01-01
Following the accretion of solids and gases in the solar nebula, the giant planets contracted to their present sizes over the age of the solar system. It is presently hypothesized that this contraction was rapid, but not hydrodynamic; at a later stage, a nebular disk out of which the regular satellites formed may have been spun out of the outer envelope of the contracting giant planets due to a combination of total angular momentum conservation and the outward transfer of specific angular momentum in the envelope. If these hypotheses are true, the composition of the irregular satellites directly reflects the composition of planetesimals from which the giant planets formed, while the composition of the regular satellites is indicative of the composition of the less volatile components of the outer envelopes of the giant planets.
Blood Lead Levels in Captive Giant Pandas.
Wintle, Nathan J P; Martin-Wintle, Meghan S; Zhou, Xiaoping; Zhang, Hemin
2018-01-01
Fifteen giant pandas (Ailuropoda melanoleuca) from the Chinese Conservation and Research Center for the Giant Panda (CCRCGP) in Bifengxia, Sichuan, China were analyzed for blood lead concentrations (Pb-B) during the 2017 breeding season. Thirteen of the 15 bears showed Pb-B below the method detection limit (MDL) of 3.3 µg/dL. The two remaining bears, although above the MDL, contained very low concentrations of lead of 3.9 and 4.5 µg/dL. All 15 giant pandas in this analysis had Pb-B concentrations that were within normal background concentrations for mammals in uncontaminated environments. For a threatened species, whose native country is plagued by reports of extremely high air pollution, our findings suggest that giant pandas at the CCRCGP are not absorbing lead at concentrations that would adversely affect their health.
Corridor connecting giant panda habitats from north to south in the Min Mountains, Sichuan, China.
Yin, Kaipu; Xie, Yan; Wu, Ning
2006-12-01
The giant panda faces severe threats from habitat fragmentation and isolation. Currently, giant panda populations have been fragmented into 30 habitat patches. The disappearance of isolated small populations and studies on the genetic diversity of various populations have shown that small isolated panda populations are at a high risk of dying out completely. Habitat fragmentation has seriously impaired the ability of the giant panda to resist climate changes and other natural disasters, such as large-scale, synchronous bamboo blooming. The Min Mountains have the largest population of pandas in China, numbering 581 individuals and accounting for 52% of the total (1114) in China. Geographic isolation means that giant pandas in the Min Mountains are divided into two populations (population A in the north and population B in the south). Population B, which had only 42 individuals in 1989, is severely threatened by high-density human populations and the loss of genetic diversity. However, we have identified an important corridor connecting the two populations. This paper explains the importance and the feasibility of reestablishing this corridor. Due to the special geographic locations of these two populations (two rivers block the migration of giant pandas between south and north), the corridor is the only passage for giant pandas in the region. Recent studies have also shown an increase of giant panda activity in the area of the corridor. However, vegetation in the corridor has been severely degraded. Bamboo forest must be restored in this area to provide food for the pandas during migration. The effects of human activities must be reduced in order to maintain panda habitat. We believe that a restored corridor will be of great benefit to the survival of giant pandas in the Min Mountains, especially for population B. Successful re-establishment of a corridor will be a valuable model for corridor construction in the future.
Mass-losing peculiar red giants - The comparison between theory and observations
NASA Technical Reports Server (NTRS)
Jura, M.
1989-01-01
The mass loss from evolved red giants is considered. It seems that red giants on the Asymptotic Giant Branch (AGB) are losing between 0.0003 and 0.0006 solar mass/sq kpc yr in the solar neighborhood. If all the main sequence stars between 1 and 5 solar masses ultimately evolve into white dwarfs with masses of 0.7 solar mass, the predicted mass loss rate in the solar neighborhood from these stars is 0.0008 solar mass/sq kpc yr. Although there are still uncertainties, it appears that there is no strong disagreement between theory and observation.
Scientific Value of a Saturn Atmospheric Probe Mission
NASA Technical Reports Server (NTRS)
Simon-Miller, A. A.; Lunine, J. I.; Atreya, S. K.; Spilker, T. R.; Coustenis, A.; Atkinson, D. H.
2012-01-01
Atmospheric entry probe mISSions to the giant planets can uniquely discriminate between competing theories of solar system formation and the origin and evolution of the giant planets and their atmospheres. This provides for important comparative studies of the gas and ice giants, and to provide a laboratory for studying the atmospheric chemistries, dynamics, and interiors of all the planets including Earth. The giant planets also represent a valuable link to extrasolar planetary systems. As outlined in the recent Planetary Decadal Survey, a Saturn Probe mission - with a shallow probe - ranks as a high priority for a New Frontiers class mission [1].
Giant cell arteritis of fallopian tube.
Azzena, A; Altavilla, G; Salmaso, R; Vasoin, F; Pellizzari, P; Doria, A
1994-01-01
One case of giant cells arteritis involving tubaric arteries in a postmenopausal woman is described. The patient was 59 years old and presented with asthenia, anemia, fever, weight loss, an abdominal palpable mass and elevated erythrocyte sedimentation rate. Exploratory laparotomy revealed a large ovarian cyst of 14 cm in diameter. Extensive giant cell arteritis, Horton's type, of the small-sizes arteries was found unexpectedly in the fallopian tube of the patient who had had a prior ovariectomy. Giant cell arteritis of the female genital tract is a rare finding in elderly women and may occur as an isolated finding or as part of generalised arteritis.
NASA Astrophysics Data System (ADS)
Raymond, S. N.; Armitage, P. J.; Moro-Martín, A.; Booth, M.; Wyatt, M. C.; Armstrong, J. C.; Mandell, A. M.; Selsis, F.; West, A. A.
2012-05-01
We present models for the formation of terrestrial planets, and the collisional evolution of debris disks, in planetary systems that contain multiple marginally unstable gas giants. We previously showed that in such systems, the dynamics of the giant planets introduces a correlation between the presence of terrestrial planets and cold dust, i.e., debris disks, which is particularly pronounced at λ ~ 70 μm. Here we present new simulations that show that this connection is qualitatively robust to a range of parameters: the mass distribution of the giant planets, the width and mass distribution of the outer planetesimal disk, and the presence of gas in the disk when the giant planets become unstable. We discuss how variations in these parameters affect the evolution. We find that systems with equal-mass giant planets undergo the most violent instabilities, and that these destroy both terrestrial planets and the outer planetesimal disks that produce debris disks. In contrast, systems with low-mass giant planets efficiently produce both terrestrial planets and debris disks. A large fraction of systems with low-mass (M ≲ 30 M⊕) outermost giant planets have final planetary separations that, scaled to the planets' masses, are as large or larger than the Saturn-Uranus and Uranus-Neptune separations in the solar system. We find that the gaps between these planets are not only dynamically stable to test particles, but are frequently populated by planetesimals. The possibility of planetesimal belts between outer giant planets should be taken into account when interpreting debris disk SEDs. In addition, the presence of ~ Earth-mass "seeds" in outer planetesimal disks causes the disks to radially spread to colder temperatures, and leads to a slow depletion of the outer planetesimal disk from the inside out. We argue that this may explain the very low frequency of >1 Gyr-old solar-type stars with observed 24 μm excesses. Our simulations do not sample the full range of plausible initial conditions for planetary systems. However, among the configurations explored, the best candidates for hosting terrestrial planets at ~1 AU are stars older than 0.1-1 Gyr with bright debris disks at 70 μm but with no currently-known giant planets. These systems combine evidence for the presence of ample rocky building blocks, with giant planet properties that are least likely to undergo destructive dynamical evolution. Thus, we predict two correlations that should be detected by upcoming surveys: an anti-correlation between debris disks and eccentric giant planets and a positive correlation between debris disks and terrestrial planets. Three movies associated to Figs. 1, 3, and 7 are available in electronic form at http://www.aanda.org
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ahmad, Mohamad M., E-mail: mmohamad@kfu.edu.sa; Department of Physics, Faculty of Science, Assiut University in the New Valley, El-Kharga 72511; Yamada, Koji
2014-04-21
In the present work, CaCu{sub 3}Ti{sub 4}O{sub 12} (CCTO) nanoceramics with different grain sizes were prepared by spark plasma sintering (SPS) at different temperatures (SPS-800, SPS-900, SPS-975, and SPS-1050) of the mechanosynthesized nano-powder. Structural and microstructural properties were studied by XRD and field-emission scanning electron microscope measurements. The grain size of CCTO nanoceramics increases from 80 nm to ∼200 nm for the ceramics sintered at 800 °C and 975 °C, respectively. Further increase of SPS temperature to 1050 °C leads to micro-sized ceramics of 2–3 μm. The electrical and dielectric properties of the investigated ceramics were studied by impedance spectroscopy. Giant dielectric constant was observed inmore » CCTO nanoceramics. The dielectric constant increases with increasing the grain size of the nanoceramics with values of 8.3 × 10{sup 3}, 2.4 × 10{sup 4}, and 3.2 × 10{sup 4} for SPS-800, SPS-900, and SPS-975, respectively. For the micro-sized SPS-1050 ceramics, the dielectric constant dropped to 2.14 × 10{sup 4}. The dielectric behavior is interpreted within the internal barrier layer capacitance picture due to the electrical inhomogeneity of the ceramics. Besides the resistive grain boundaries that are usually observed in CCTO ceramics, domain boundaries appear as a second source of internal layers in the current nanoceramics.« less
La Pira, Biagia; Brinjikji, Waleed; Burrows, Anthony M; Cloft, Harry J; Vine, Roanna L; Lanzino, Giuseppe
2016-11-01
Internal carotid artery bifurcation aneurysms (ICAbifAs) present unique challenges to endovascular and surgical operators, and little is known about their natural history. We reviewed our institution's experience with ICAbifAs studying outcomes of surgical and endovascular management and natural history. Consecutive patients with unruptured ICAbifAs evaluated and/or treated over an 8-year interval were studied. Baseline demographics, neurovascular risk factors, aneurysm location and size, clinical presentation, treatment recommendations, and outcomes were prospectively collected and retrospectively analyzed. Continuous variables were compared with Student's t test and categorical variables with Chi-square tests. Fifty-nine patients with 61 unruptured ICAbifAs were included. Seven aneurysms were treated surgically (11.5 %), 22 underwent endovascular treatment (36 %), and 32 were managed conservatively (52.5 %). In the surgical group, short- and long-term complete aneurysm occlusion rates were 100 % with no cases of perioperative or long-term permanent morbidity or treatment-related mortality. In the endovascular group, two patients (11.7 %) with giant aneurysms had perioperative thromboembolic events with transient morbidity. There was one case of aneurysm rupture at follow-up in a giant aneurysm treated with partial coil embolization. Complete/near-complete occlusion rates were 63 %. There was one case of aneurysm rupture after 114 aneurysm-years of follow-up in the conservative management group (0.89 %/year), but no ruptures were observed in small aneurysms selected for conservative management. Unruptured small ICAbifAs have a benign natural history. In patients selected for treatment, excellent results can be achieved in the vast majority of patients with judicious use of endovascular and surgical therapy.
Ono, Hideaki; Inoue, Tomohiro; Tanishima, Takeo; Tamura, Akira; Saito, Isamu; Saito, Nobuhito
2018-04-01
High-flow bypass followed by ligation of the internal carotid artery (ICA) is an effective treatment, but the impact of abrupt occlusion of the ICA is unpredictable, especially on postoperative cognitive function. The present study evaluated the clinical results as well as cognitive performances after high-flow bypass using radial artery graft (RAG) with supportive superficial temporal artery (STA)-middle cerebral artery (MCA) bypass, followed by ICA ligation. Ten consecutive patients underwent high-flow bypass surgery for large or giant ICA aneurysms of cavernous or cervical portion. Demographics, clinical information, magnetic resonance (MR) imaging, computed tomography, digital subtraction angiography (DSA), intraoperative somatosensory evoked potentials, neuropsychological examinations including the Wechsler Adult Intelligence Scale-Third Edition and the Wechsler Memory Scale-Revised (WMS-R), and follow-up data were analyzed. The aneurysm was located on the cavernous segment in eight cases and cervical segment in two cases, and mean aneurysm size was 27.9 mm. Postoperative DSA demonstrated robust bypass flow from the external carotid artery to MCA via the RAG, and no anterograde flow into the aneurysm. No patient showed new symptoms after the operation. Follow-up clinical study and MR imaging were performed in nine patients and showed no additional ischemic lesion compared with preoperative imaging. Seven patients completed neuropsychological examinations before and after surgery. All postoperative scores except WMS-R composite memory score slightly improved. High-flow bypass followed by ICA ligation can achieve good clinical outcomes. Successful high-flow bypass using RAG with supportive STA-MCA bypass and ICA ligation does not adversely affect postoperative cognitive function.
Atmospheric Dynamics of the Outer Planets
NASA Technical Reports Server (NTRS)
Ingersoll, Andrew P.
2002-01-01
The giant planets-Jupiter, Saturn, Uranus, and Neptune-are fluid objects. The winds are powered by absorbed sunlight, as on earth, and by internal heat left over from planetary formation. The main constituents of the atmospheres are hydrogen and helium. The clouds are made of ammonia, hydrogen sulphide, and water. All four giant planets are banded, with multiple zonal jet streams. Even Uranus, whose spin axis is tipped by 98deg relative to the orbit axis, shows latitudinal banding and zonal jets. Equator-to-pole temperature differences are close to zero. Wind speeds are larger than on earth and do not decrease with distance from the sun. Although the power/area at Neptune is only 1/20 that at Jupiter, the winds at Neptune are three times stronger. Stable vortices like the Great Red Spot of Jupiter and similar spots on Neptune come in all size ranges and exhibit a variety of behaviours including merging, orbiting, filament ejection, and oscillating in both shape and position. At least at cloud-top levels, 90% of the long-lived vortices are anticyclonic and sit in anticyclonic shear zones. Features in the cyclonic zones tend to be chaotic, with lifetimes of several days or less. These mesoscale eddies tend to have lightning in them, which suggests that they get their energy from moist convection. The rate of conversion of eddy kinetic energy into kinetic energy of the zonal jets is more than 10% of the power/area radiated by Jupiter. This fraction is more than an order of magnitude larger than on earth. Several lines of evidence now indicate that the winds at cloud-top levels are the surface manifestation of deep-rooted motions that extend into the interior and are presumably driven by internal heat.
DISCOVERY OF RELATIVELY HYDROGEN-POOR GIANTS IN THE GALACTIC GLOBULAR CLUSTER ω CENTAURI
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hema, B. P.; Pandey, Gajendra, E-mail: hema@iiap.res.in, E-mail: pandey@iiap.res.in
2014-09-10
In this Letter, the results of our low-resolution spectroscopic survey for identifying hydrogen-deficient stars in the red giant sample of the globular cluster ω Cen are reported. Spectral analyses were carried out on the basis of the strengths of the (0, 0) MgH band and the Mg b triplet. In our sample, four giants were identified with weak/absent MgH bands in their observed spectra, which was unexpected for their well determined stellar parameters. The Mg abundances for the program stars were determined from the subordinate lines of the MgH band to the blue of the Mg b triplet, using the spectral synthesis technique. Themore » derived Mg abundances for the program stars were as expected for the red giants of ω Cen, except for the four identified candidates. The determined Mg abundances of these four candidates are much lower than that expected for the red giants of ω Cen, and are unacceptable based on the strengths of the Mg b triplet in their observed spectra. Hence, a plausible explanation for the weak/absent MgH bands in the observed spectra of these stars is a relatively lower abundance of hydrogen in their atmospheres. These giants may belong to the group of helium-enriched red giants of ω Cen.« less
Jin, Ke; Xue, Chenyi; Wu, Xiaoli; Qian, Jinyi; Zhu, Yong; Yang, Zhen; Yonezawa, Takahiro; Crabbe, M James C; Cao, Ying; Hasegawa, Masami; Zhong, Yang; Zheng, Yufang
2011-01-01
The giant panda has an interesting bamboo diet unlike the other species in the order of Carnivora. The umami taste receptor gene T1R1 has been identified as a pseudogene during its genome sequencing project and confirmed using a different giant panda sample. The estimated mutation time for this gene is about 4.2 Myr. Such mutation coincided with the giant panda's dietary change and also reinforced its herbivorous life style. However, as this gene is preserved in herbivores such as cow and horse, we need to look for other reasons behind the giant panda's diet switch. Since taste is part of the reward properties of food related to its energy and nutrition contents, we did a systematic analysis on those genes involved in the appetite-reward system for the giant panda. We extracted the giant panda sequence information for those genes and compared with the human sequence first and then with seven other species including chimpanzee, mouse, rat, dog, cat, horse, and cow. Orthologs in panda were further analyzed based on the coding region, Kozak consensus sequence, and potential microRNA binding of those genes. Our results revealed an interesting dopamine metabolic involvement in the panda's food choice. This finding suggests a new direction for molecular evolution studies behind the panda's dietary switch.
Jin, Ke; Xue, Chenyi; Wu, Xiaoli; Qian, Jinyi; Zhu, Yong; Yang, Zhen; Yonezawa, Takahiro; Crabbe, M. James C.; Cao, Ying; Hasegawa, Masami; Zhong, Yang; Zheng, Yufang
2011-01-01
Background The giant panda has an interesting bamboo diet unlike the other species in the order of Carnivora. The umami taste receptor gene T1R1 has been identified as a pseudogene during its genome sequencing project and confirmed using a different giant panda sample. The estimated mutation time for this gene is about 4.2 Myr. Such mutation coincided with the giant panda's dietary change and also reinforced its herbivorous life style. However, as this gene is preserved in herbivores such as cow and horse, we need to look for other reasons behind the giant panda's diet switch. Methodology/Principal Findings Since taste is part of the reward properties of food related to its energy and nutrition contents, we did a systematic analysis on those genes involved in the appetite-reward system for the giant panda. We extracted the giant panda sequence information for those genes and compared with the human sequence first and then with seven other species including chimpanzee, mouse, rat, dog, cat, horse, and cow. Orthologs in panda were further analyzed based on the coding region, Kozak consensus sequence, and potential microRNA binding of those genes. Conclusions/Significance Our results revealed an interesting dopamine metabolic involvement in the panda's food choice. This finding suggests a new direction for molecular evolution studies behind the panda's dietary switch. PMID:21818345
Bowater, R O; Forbes-Faulkner, J; Anderson, I G; Condon, K; Robinson, B; Kong, F; Gilbert, G L; Reynolds, A; Hyland, S; McPherson, G; Brien, J O'; Blyde, D
2012-03-01
Ninety-three giant Queensland grouper, Epinephelus lanceolatus (Bloch), were found dead in Queensland, Australia, from 2007 to 2011. Most dead fish occurred in northern Queensland, with a peak of mortalities in Cairns in June 2008. In 2009, sick wild fish including giant sea catfish, Arius thalassinus (Rüppell), and javelin grunter, Pomadasys kaakan (Cuvier), also occurred in Cairns. In 2009 and 2010, two disease epizootics involving wild stingrays occurred at Sea World marine aquarium. Necropsy, histopathology, bacteriology and PCR determined that the cause of deaths of 12 giant Queensland grouper, three wild fish, six estuary rays, Dasyatis fluviorum (Ogilby), one mangrove whipray, Himantura granulata (Macleay), and one eastern shovelnose ray, Aptychotrema rostrata (Shaw), was Streptococcus agalactiae septicaemia. Biochemical testing of 34 S. agalactiae isolates from giant Queensland grouper, wild fish and stingrays showed all had identical biochemical profiles. The 16S rRNA gene sequences of isolates confirmed all isolates were S. agalactiae; genotyping of selected S. agalactiae isolates showed the isolates from giant Queensland grouper were serotype Ib, whereas isolates from wild fish and stingrays closely resembled serotype II. This is the first report of S. agalactiae from wild giant Queensland grouper and other wild tropical fish and stingray species in Queensland, Australia. © 2012 Blackwell Publishing Ltd and State of Queensland.