Blade-order-dependent radiocarbon variability in brown seaweed (Undaria pinnatifida) reflected a cold Oyashio water intrusion event in an embayment of the Sanriku coast, northeastern Japan

NASA Astrophysics Data System (ADS)

Satoh, N.; Fukuda, H.; Miyairi, Y.; Yokoyama, Y.; Nagata, T.

2015-12-01

Radiocarbon in dissolved inorganic carbon (DIC) in seawater varies greatly, both geographically and with depth. This "reservoir effect" is thought to be reflected in the radiocarbon content (Δ14C) of marine organisms, via DIC fixation by primary producers and subsequent trophic transfer. The Δ14C of marine organismal soft tissues might thus provide unique information about their habitats, diets, migration and other environmental histories. However, the effectiveness of this approach has yet to be extensively explored, with data on Δ14C variability in soft tissues of marine organisms being markedly limited. Here we examined whether Δ14C values of individual pinnate blades (leaf-like structures) of brown seaweed (Undaria pinnatifida) reflect the Δ14C of DIC in the water current prevailing at the time of blade formation. The study was conducted in Otsuchi Bay located in the Sanriku coastal region, northeastern Japan, where 14C-depleted cold Oyashio current and warm Tsugaru current (high Δ14C) converge, affecting the physiology and growth of marine organisms growing there. U. pinnatifida individuals cultured in the bay (length of saprophytes, 140-215 cm) were harvested in April 2014 and Δ14C of blades were determined by accelerator mass spectrometry. Younger blades formed after the Oyashio water intrusion had significantly lower Δ14C values compared to older blades formed before the event. The Δ14C values of younger and older blades were generally consistent with the Δ14C of DIC in Oyashio (-60.5 ‰) and Tsugaru (24.9 ‰) waters, respectively. Thus, despite possible turnover of organic carbon in seaweed soft tissues, blade-order-dependent Δ14C variability appeared to strongly reflect the Oyashio intrusion event (radiocarbon shift) in the bay.

Anti-metastasis effect of fucoidan from Undaria pinnatifida sporophylls in mouse hepatocarcinoma Hca-F cells.

PubMed

Wang, Peisheng; Liu, Zhichao; Liu, Xianli; Teng, Hongming; Zhang, Cuili; Hou, Lin; Zou, Xiangyang

2014-01-01

Metastasis is one of the major causes of cancer-related death. It is a complex biological process involving multiple genes, steps, and phases. It is also closely connected to many biological activities of cancer cells, such as growth, invasion, adhesion, hematogenous metastasis, and lymphatic metastasis. Fucoidan derived from Undaria pinnatifida sporophylls (Ups-fucoidan) is a sulfated polysaccharide with more biological activities than other fucoidans. However, there is no information on the effects of Ups-fucoidan on tumor invasion and metastasis. We used the mouse hepatocarcinoma Hca-F cell line, which has high invasive and lymphatic metastasis potential in vitro and in vivo, to examine the effect of Ups-fucoidan on cancer cell invasion and metastasis. Ups-fucoidan exerted a concentration- and time-dependent inhibitory effect on tumor metastasis in vivo and inhibited Hca-F cell growth, migration, invasion, and adhesion capabilities in vitro. Ups-fucoidan inhibited growth and metastasis by downregulating vascular endothelial growth factor (VEGF) C/VEGF receptor 3, hepatocyte growth factor/c-MET, cyclin D1, cyclin-dependent kinase 4, phosphorylated (p) phosphoinositide 3-kinase, p-Akt, p-extracellular signal regulated kinase (ERK) 1/2, and nuclear transcription factor-κB (NF-κB), and suppressed adhesion and invasion by downregulating L-Selectin, and upregulating protein levels of tissue inhibitor of metalloproteinases (TIMPs). The results suggest that Ups-fucoidan suppresses Hca-F cell growth, adhesion, invasion, and metastasis capabilities and that these functions are mediated through the mechanism involving inactivation of the NF-κB pathway mediated by PI3K/Akt and ERK signaling pathways.

Anti-Metastasis Effect of Fucoidan from Undaria pinnatifida Sporophylls in Mouse Hepatocarcinoma Hca-F Cells

PubMed Central

Wang, Peisheng; Liu, Zhichao; Liu, Xianli; Teng, Hongming; Zhang, Cuili; Hou, Lin; Zou, Xiangyang

2014-01-01

Metastasis is one of the major causes of cancer-related death. It is a complex biological process involving multiple genes, steps, and phases. It is also closely connected to many biological activities of cancer cells, such as growth, invasion, adhesion, hematogenous metastasis, and lymphatic metastasis. Fucoidan derived from Undaria pinnatifida sporophylls (Ups-fucoidan) is a sulfated polysaccharide with more biological activities than other fucoidans. However, there is no information on the effects of Ups-fucoidan on tumor invasion and metastasis. We used the mouse hepatocarcinoma Hca-F cell line, which has high invasive and lymphatic metastasis potential in vitro and in vivo, to examine the effect of Ups-fucoidan on cancer cell invasion and metastasis. Ups-fucoidan exerted a concentration- and time-dependent inhibitory effect on tumor metastasis in vivo and inhibited Hca-F cell growth, migration, invasion, and adhesion capabilities in vitro. Ups-fucoidan inhibited growth and metastasis by downregulating vascular endothelial growth factor (VEGF) C/VEGF receptor 3, hepatocyte growth factor/c-MET, cyclin D1, cyclin-dependent kinase 4, phosphorylated (p) phosphoinositide 3-kinase, p-Akt, p-extracellular signal regulated kinase (ERK) 1/2, and nuclear transcription factor-κB (NF-κB), and suppressed adhesion and invasion by downregulating L-Selectin, and upregulating protein levels of tissue inhibitor of metalloproteinases (TIMPs). The results suggest that Ups-fucoidan suppresses Hca-F cell growth, adhesion, invasion, and metastasis capabilities and that these functions are mediated through the mechanism involving inactivation of the NF-κB pathway mediated by PI3K/Akt and ERK signaling pathways. PMID:25162296

Fucoxanthin Inhibits the Inflammation Response in Paw Edema Model through Suppressing MAPKs, Akt, and NFκB.

PubMed

Choi, Jun-Hui; Kim, Na-Hyun; Kim, Sung-Jun; Lee, Hyo-Jeong; Kim, Seung

2016-03-01

Undaria pinnatifida is a well-known traditional Korean food with a variety of biological activities. Carrageenan (carr) is commonly used to induce paw edema in animal models. This study was designed to elucidate the processes underlying the anti-inflammatory effect of fucoxanthin isolated from the sporophyll of U. pinnatifida in carr-induced paw edema in ICR mice. Fucoxanthin significantly decreased carr-induced increased nitric oxide levels in the plasma of mice with carr-induced paw edema. Fucoxanthin protected catalase (CAT) and superoxide dismutase (SOD) activity against disruption in mice with carr-induced paw edema. In addition, fucoxanthin repressed carr-induced activation of inducible nitric oxide synthase, cyclooxygenase-2, and nuclear factor kappa B, as well as carr-induced phosphorylation of mitogen-activated protein kinase, extracellular signal-regulated kinase, c-Jun N-terminal kinase, p38, and protein kinase B/Akt. These results suggest that fucoxanthin may have therapeutic potential as a treatment for patients with inflammatory diseases. © 2015 Wiley Periodicals, Inc.

Intraspecific crossings of Undaria pinnatifida (Harv.) Sur.—A possible time-saving way of strain selection

NASA Astrophysics Data System (ADS)

Pang, Shao-Jun; Hu, Xiao-Yan; Wu, Chao-Yuan; Hirosawa, A.; Ohno, M.

1997-09-01

Unicellular gametophytes of Undaria pinnatifida (Harv.) Sur. were isolated in Qingdao, P. R. China in April 1993 and in Tokushima, southern Japan in March 1995. Different intraspecific crossings by using unicellular male and female gametophytes were successfully undertaken in Sept. of 1995 in Qingdao. Sporophytes were transplanted to two different locations for open sea cultivation. One was at Zhanqiao (ZQ) Bay where the water current was slower than that of another location—Taipingjiao(TPJ). A total of 218 adult sporophytes were harvested on January 12 and 18 from TPJ and ZQ respectively. For eacn combination, 10 sporophytes were cultivated. Analysis of the morphological characteristics of adult sporophytes indicated that the longest length between two bases of the serration of pinnate blades (W2) is a morphological characteristic that can be transferred from the parent plant to the next generations regardless of environmental variations. There was evidence that W2 was apparently determined by sex-linked factors, i.e., by male parental gametophyte. Sporophytes from certain crossing combinations showed more vigorous growth than those from other crossing combinations. It is therefore possible to select gametophyte strains which can be used as parental gametophytes for the seedling production of sporophytes with more vigorous growth within shorter cultivation period. The morphology of hybrids from a Qingdao strain and a Tokushima cultivated strain resembled that of both parental plants in frond features (wrinkled or smooth) and W2. Sporophyll formation also varied with strains. The fact that adult sporophytes resulting from the same crossing combinations have identical morphological characteristics under the same environmental conditions indicates the possibility of a new way to select strains which are expected to be ideal for commerical production by purposely selecting, propagating, and seeding unicellular gametophytes for sporeling production through freeliving techniques of gametophytes.

Comparison of Saccharina japonica-Undaria pinnatifida Mixture and Minoxidil on Hair Growth Promoting Effect in Mice.

PubMed

Park, Ki Soo; Park, Dae Hwan

2016-11-01

Algae have traditionally been used for promotion of hair growth. Use of hair regrowth drugs, such as minoxidil, is limited due to side effects. The aim of this study was to examine a mixture of Saccharina japonica and Undaria pinnatifida (L-U mixture) on hair growth and to compare the promoting effect of hair growth by a 3% minoxidil and a L-U mixture. To evaluate the hair growth-promoting activity, saline, 50% ethanol, 3% minoxidil, and the L-U mixture were applied 2 times a day for a total of 14 days on the dorsal skin of C57BL/6 mice after depilation. Analysis was determined by using a high-resolution hair analysis system, real-time polymerase chain reaction, and H&E staining. On day 14, the hair growth effect of the L-U mixture was the same as that of the 3% minoxidil treatment. The L-U mixture significantly (P<0.05) stimulated hair growth-promoting genes, as vascular endothelial growth factor (VEGF) and insulin-like growth factor -1. Increase of VEGF was observed in the L-U mixture group compared with minoxidil and the negative control. In contrast, the L-U mixture suppressed the expression of transforming growth factor-β1, which is the hair loss-related gene. In histological examination in the L-U mixture and minoxidil groups, the induction of an anagen stage of hair follicles was faster than that of control groups. This study provides evidence that the L-U mixture can promote hair growth in mice, similar to the effect from minoxidil, and suggests that there is potential application for hair loss treatments.

Arsenic Species in Edible Seaweeds Using In Vitro Biomimetic Digestion Determined by High-Performance Liquid Chromatography Inductively Coupled Plasma Mass Spectrometry

PubMed Central

Zhao, Yan-Fang; Wu, Ji-Fa; Shang, De-Rong; Ning, Jin-Song; Ding, Hai-Yan; Zhai, Yu-Xiu

2014-01-01

Arsenite [As (III)], arsenate [As (V)], methylarsonate (MMA), and dimethylarsinate (DMA) in five edible seaweeds (the brown algae Laminaria japonica, red algae Porphyra yezoensis, brown algae Undaria pinnatifida, brown algae Hizikia fusiformis, and green algae Enteromorpha prolifera) were analyzed using in vitro digestion method determined by high-performance liquid chromatography inductively coupled plasma mass spectrometry. The results showed that DMA was found in the water extracts of all samples; As (III) were detected in L. japonica and U. pinnatifida and about 23.0 and 0.15 mg/kg of As (V) were found in H. fusiformis and E. prolifera respectively. However, after the gastrointestinal digestion, As (V) was not detected in any of the five seaweeds. About 0.19 and 1.47 mg/kg of As (III) was detected in the gastric extracts of L. japonica and H. fusiformis, respectively, and about 0.31 and 0.10 mg/kg of As (III) were extracted from the intestinal extracts of Porphyra yezoensis and U. pinnatifida, respectively. The present results successfully reveal the differences of As species and levels in the water and biomimetic extracts of five edible seaweeds. The risk assessment of the inorganic arsenic in the five edible seaweeds based on present data showed almost no hazards to human health. PMID:26904630

Evaluation of innate immune stimulating activity of polysaccharides using a silkworm (Bombyx mori) muscle contraction assay.

PubMed

Fujiyuki, T; Hamamoto, H; Ishii, K; Urai, M; Kataoka, K; Takeda, T; Shibata, S; Sekimizu, K

2012-04-01

In silkworm larvae, the mature form of paralytic peptide (PP), an insect cytokine, is produced from pro-PP in association with activation of innate immune responses, resulting in slow muscle contraction. We utilized this reaction, muscle contraction in silkworms coupled with innate immunity stimulation, to quantitatively measure the innate immune stimulating activity of various natural polysaccharides. β-Glucan of Gyrophora esculenta (GE-3), fucoidan from sporophyll of Undaria pinnatifida, and curldan induced silkworm muscle contraction. We further demonstrated that GE-3 had therapeutic effects on silkworms infected by baculovirus. Based on these findings, we propose that the silkworm muscle contraction assay is useful for screening substances that stimulate innate immunity before evaluating therapeutic effectiveness in mammals.

Antiobesity effects of Undaria lipid capsules prepared with scallop phospholipids.

PubMed

Okada, Tomoko; Mizuno, Yasuyuki; Sibayama, Shinichi; Hosokawa, Masashi; Miyashita, Kazuo

2011-01-01

Based on previous research findings, a capsule was developed containing n-3 polyunsaturated fatty acid rich scallop phospholipids (PLs) with an incorporation of brown seaweed (Undaria pinnatifida) lipids (ULs) containing fucoxanthin. The antiobesity effects of the capsules were evaluated with an animal model using 3-wk-old male KK-A(y) mice. Each group received different combinations of lipid (UL, PL, UL + PL, or UL + PL capsule) either incorporated into the diet or into drinking water. Animals were sacrificed after a 4-wk experimental feeding period, and adipose tissues and organs were dissected and weighed. Blood samples were obtained to determine plasma lipid profiles. Uncoupling protein 1 (UCP1) mRNA expression levels were determined by real-time polymerase chain reaction analysis, and UCP1 expression was determined by western blotting analysis. Treatment with either UL alone or UL + PL (capsule) through drinking water resulted in a significant reduction in body weight, compared to the control group. The total white adipose tissue weight of mice fed the UL + PL capsule in drinking water was significantly reduced. Both UCP1 and UCP1 mRNA expression in epididymal fat from mice fed the capsule were significantly higher than in the control group. These results suggest that incorporation of UL into scallop-derived PL by means of capsulation may lead to an additive increase in the antiobesity properties of these bioactive lipids.

Phenolic content and antioxidant capacity in algal food products.

PubMed

Machu, Ludmila; Misurcova, Ladislava; Ambrozova, Jarmila Vavra; Orsavova, Jana; Mlcek, Jiri; Sochor, Jiri; Jurikova, Tunde

2015-01-12

The study objective was to investigate total phenolic content using Folin-Ciocalteu's method, to assess nine phenols by HPLC, to determine antioxidant capacity of the water soluble compounds (ACW) by a photochemiluminescence method, and to calculate the correlation coefficients in commercial algal food products from brown (Laminaria japonica, Eisenia bicyclis, Hizikia fusiformis, Undaria pinnatifida) and red (Porphyra tenera, Palmaria palmata) seaweed, green freshwater algae (Chlorella pyrenoidosa), and cyanobacteria (Spirulina platensis). HPLC analysis showed that the most abundant phenolic compound was epicatechin. From spectrophotometry and ACW determination it was evident that brown seaweed Eisenia bicyclis was the sample with the highest phenolic and ACW values (193 mg·g-1 GAE; 7.53 µmol AA·g-1, respectively). A linear relationship existed between ACW and phenolic contents (r = 0.99). Some algal products seem to be promising functional foods rich in polyphenols.

Brown seaweed pigment as a dye source for photoelectrochemical solar cells

NASA Astrophysics Data System (ADS)

Calogero, Giuseppe; Citro, Ilaria; Di Marco, Gaetano; Armeli Minicante, Simona; Morabito, Marina; Genovese, Giuseppa

2014-01-01

Chlorophylls based-dyes obtained from seaweeds represent attractive alternatives to the expensive and polluting pyridil based Ru complexes because of their abundance in nature. Another important characteristic is that the algae do not subtract either cropland or agricultural water, therefore do not conflict with agro-food sector. This pigment shows a typical intense absorption in the UV/blue (Soret band) and a less intense band in the red/near IR (Q band) spectral regions and for these reasons appear very promising as sensitizer dyes for DSSC. In the present study, we utilized chlorophylls from samples of the brown alga Undaria pinnatifida as sensitizer in DSSCs. The dye, extracted by frozen seaweeds and used without any chemical purification, showed a very good fill factor (0.69). Even the photelectrochemical parameters if compared with the existent literature are very interesting.

Hydrothermal liquefaction of Undaria pinnatifida residues to organic acids with recyclable trimethylamine.

PubMed

Chen, Yongxing; Ren, Xiulian; Wei, Qifeng; Guo, Jingjing

2016-12-01

This study investigated the effect of trimethylamine (TMA) on the hydrothermal liquefaction (HTL) process and the recycle of TMA. The results suggest that the peeling reaction occurred on the surface and the cleavage of cellulose leading to water-soluble substances and bio-oil. The highest content of organic acids was found in the water-soluble phase. Model compounds, different glucides with TMA were used to investigate the mechanism of the HTL. Results suggest that the OH - appeared to selectively interact with C-O-C bonds, and thus causing the key linkages of cellulose to become much easier to be cleaved under mild conditions. In addition, the conditions for TMA recovery were optimized and the highest TMA recovery rate reached 98.89%. The recovered TMA had the same properties as the original compound, and it was perfectly re-usable in the conversion process of HTL. Copyright © 2016 Elsevier Ltd. All rights reserved.

Optimization for Reduced-Fat / Low-NaCl Meat Emulsion Systems with Sea Mustard (Undaria pinnatifida) and Phosphate

PubMed Central

Kim, Cheon-Jei; Hwang, Ko-Eun; Song, Dong-Heon; Jeong, Tae-Jun; Kim, Hyun-Wook

2015-01-01

The effects of reducing fat levels from 30% to 20% and salt concentrations from 1.5% to 1.0% by partially substituting incorporated phosphate and sea mustard were investigated based on physicochemical properties of reduced-fat / low-NaCl meat emulsion systems. Cooking loss and emulsion stability, hardness, springiness, and cohesiveness for reduced-fat / low-NaCl meat emulsion systems with 20% pork back fat and 1.2% sodium chloride samples with incorporation of phosphate and sea mustard were similar to the control with 30% pork back fat and 1.5% sodium chloride. Results showed that reduced-fat / low-NaCl meat emulsion system samples containing phosphate and sea mustard had higher apparent viscosity. The results of this study show that the incorporation of phosphate and sea mustard in the formulation will successfully reduce fat and salt in the final meat products. PMID:26761874

Brown algae hydrolysis in 1-n-butyl-3-methylimidazolium chloride with mineral acid catalyst system.

PubMed

Malihan, Lenny B; Nisola, Grace M; Chung, Wook-Jin

2012-08-01

The amenability of three brown algal species, Sargassum fulvellum, Laminaria japonica and Undaria pinnatifida, to hydrolysis were investigated using the ionic liquid (IL), 1-n-butyl-3-methylimidazolium chloride ([BMIM]Cl). Compositional analyses of the brown algae reveal that sufficient amounts of sugars (15.5-29.4 wt.%) can be recovered. Results from hydrolysis experiments show that careful selection of the type of mineral acid as catalyst and control of acid loading could maximize the recovery of sugars. Optimal reaction time and temperature were determined from the kinetic studies on the sequential reducing sugar (TRS) formation and degradation. Optimal reaction times were determined based on the extent of furfurals formation as TRS degradation products. X-ray diffraction and environmental scanning electron microscopy confirmed the suitability of [BMIM]Cl as solvent for the hydrolysis of the three brown algae. Overall results show the potential of brown algae as renewable energy resources for the production of valuable chemicals and biofuels. Copyright © 2012 Elsevier Ltd. All rights reserved.

The marine alga Gelidium amansii promotes the development and complexity of neuronal cytoarchitecture.

PubMed

Hannan, Abdul; Kang, Ji-Young; Hong, Yong-Ki; Lee, Hyunsook; Choi, Jae-Suk; Choi, In Soon; Moon, Il Soo

2013-01-01

Neurotrophic factors are vital not only to support neuronal development but also to protect mature neurons from atrophy in neurodegenerative diseases. As an effort to explore natural sources that possess neurotrophic activity, we screened common marine algae for their neuritogenic activity in the developing rat hippocampal neurons in culture. Of the 22 seaweed species examined, ethanol extracts of Gelidium amansii (GAE) exhibited potent neuritogenic activity, followed by Undaria pinnatifida and Sargassum fulvellum extracts. The effects of GAE were dose dependent with an optimum concentration of 15 µg/mL. The GAE significantly promoted the initial neuronal differentiation from the stage I into the stage II and increased the indices of axonal and dendritic development such as the length, the numbers of primary processes, and branching frequencies by a minimum of twofold compared with the vehicle control. These results show that marine algae are promising candidates for neurotrophic potentials. Copyright © 2012 John Wiley & Sons, Ltd.

Effects of the intake of Undaria pinnatifida (Wakame) and its sporophylls (Mekabu) on postprandial glucose and insulin metabolism.

PubMed

Tanemura, Yoko; Yamanaka-Okumura, Hisami; Sakuma, Masae; Nii, Yoshitaka; Taketani, Yutaka; Takeda, Eiji

2014-01-01

Long-term suppression of postprandial glucose concentration is an important dietary strategy for the prevention and treatment of type 2 diabetes. Because previous reports have suggested that seaweed may exert anti-diabetic effects in animals, the effects of Wakame or Mekabu intake with 200 g white rice, 50 g boiled soybeans, 60 g potatoes, and 40 g broccoli on postprandial glucose, insulin and free fatty acid levels were investigated in healthy subjects. Plasma glucose levels at 30 min and glucose area under the curve (AUC) at 0-30 min after the Mekabu meal were significantly lower than that after the control meal. Plasma glucose and glucose AUC were not different between the Wakame and control meals. Postprandial serum insulin and its AUC and free fatty acid concentration were not different among the three meals. In addition, fullness, satisfaction, and wellness scores were not different among the three meals. Thus, consumption of 70 g Mekabu with a white rice-based breakfast reduces postprandial glucose concentration.

Development of a seaweed species-selection index for successful culture in a seaweed-based integrated aquaculture system

NASA Astrophysics Data System (ADS)

Kang, Yun Hee; Hwang, Jae Ran; Chung, Ik Kyo; Park, Sang Rul

2013-03-01

Integrated multi-trophic aquaculture (IMTA) has been proposed as a concept that combines the cultivation of fed aquaculture species ( e.g., finfish/shrimp) with extractive aquaculture species ( e.g., shellfish/seaweed). In seaweed-based integrated aquaculture, seaweeds have the capacity to reduce the environmental impact of nitrogen-rich effluents on coastal ecosystems. Thus, selection of optimal species for such aquaculture is of great importance. The present study aimed to develop a seaweed species-selection index for selecting suitable species in seaweed-based integrated aquaculture system. The index was synthesized using available literature-based information, reference data, and physiological seaweed experiments to identify and prioritize the desired species. Undaria pinnatifida, Porphyra yezoensis and Ulva compressa scored the highest according to a seaweed-based integrated aquaculture suitability index (SASI). Seaweed species with the highest scores were adjudged to fit the integrated aquaculture systems. Despite the application of this model limited by local aquaculture environment, it is considered to be a useful tool for selecting seaweed species in IMTA.

The microbiota of eight species of dehydrated edible seaweeds from North West Spain.

PubMed

Del Olmo, Ana; Picon, Antonia; Nuñez, Manuel

2018-04-01

The microbiota of eight species (Chondrus crispus, Himanthalia elongata, Laminaria ochroleuca, Palmaria palmata, Porphyra umbilicalis, Saccharina latissima, Ulva lactuca and Undaria pinnatifida) of edible seaweeds collected in North West Spain, marketed as dehydrated product, was quantitatively determined on nine solid media. Representative colonies were selected from solid culture media. The isolated microorganisms were identified by means of morphological characteristics, 16S rDNA sequencing and biochemical tests. U. pinnatifida was the seaweed species showing the most abundant microbial population, with counts on Marine agar up to 7.7 log cfu/g in individual samples and 5.0 log cfu/g as the mean value, and counts of coliforms up to 4.6 log cfu/g in individual samples and 2.4 log cfu/g as the mean value. The 225 identified bacterial isolates belonged to 11 families, 27 genera and 56 species. Bacillaceae was the family accounting for the highest number of isolates (111) followed by Enterobacteriaceae (60), Bacillales Family XII Incertae Sedis (20), Planococcaceae (11), Moraxellaceae (7), Paenibacillaceae (5) and Pseudomonadaceae (5). Bacterial species showing the highest occurrence in dehydrated seaweeds were Bacillus megaterium, B. licheniformis, Pantoea sp. and termoresistant Pantoea sp. Four of the Bacillus species isolated from dehydrated seaweeds (B. cereus, B. licheniformis, B. pumilus and B. subtilis) are among those containing strains considered to be foodborne pathogens and nine of the isolated non-Bacillales bacterial species have been reported to contain human opportunistic pathogenic strains. Copyright © 2017 Elsevier Ltd. All rights reserved.

Nutritional and bioactive compounds of commercialized algae powders used as food supplements.

PubMed

Martínez-Hernández, Ginés B; Castillejo, Noelia; Carrión-Monteagudo, María Del M; Artés, Francisco; Artés-Hernández, Francisco

2018-03-01

The main nutritional/bioactive compounds (protein; aminoacids, AA; fucose; minerals; vitamins B12 and C; and total phenolic content, TPC) of nine commercial algae powders, used as food supplements, were studied. Undaria pinnatifida showed the highest protein/aminoacid contents (51.6/54.4 g 100 g -1 ). Among brown macroalgae, Himanthalia elongata showed the highest fucose content (26.3 g kg -1 ) followed by Laminaria ochroleuca (22.5 g kg -1 ). Mineral contents of 15-24% were observed in the algae, being particularly excellent sources of iodine (69.0-472.0 mg kg -1 ). Porphyra spp. and Palmaria palmata showed the highest vitamin B12 contents (667-674 µg kg -1 ). Vitamin C ranged among 490.4-711.8 mg kg -1 . H. elongata showed the highest total phenolic content (14.0 g kg -1 ). In conclusion, the studied algae are excellent sources of protein, AA, minerals, vitamin C and some of them presented particularly high vitamin B12 and fucose contents, which may have a potential use as food supplements.

Development of an eco-protocol for seaweed chlorophylls extraction and possible applications in dye sensitized solar cells

NASA Astrophysics Data System (ADS)

Armeli Minicante, S.; Ambrosi, E.; Back, M.; Barichello, J.; Cattaruzza, E.; Gonella, F.; Scantamburlo, E.; Trave, E.

2016-07-01

Seaweeds are a reserve of natural dyes (chlorophylls a, b and c), characterized by low cost and easy supply, without potential environmental load in terms of land subtraction, and also complying with the requirements of an efficient waste management policy. In particular, the brown seaweed Undaria pinnatifida is a species largely present in the Venice Lagoon area, and for it a removal strategy is actually mandatory. In this paper, we set-up an eco-protocol for the best extraction and preparation procedures of the pigment, with the aim of finding an easy and affordable method for chlorophyll c extraction, exploring at the same time the possibility of using these algae within local sustainable management integrated strategies, among which the possible use of chlorophylls as a dye source in dye sensitized solar cells (DSSCs) is investigated. Experimental results suggest that the developed protocols are useful to optimize the chlorophyll c extraction, as shown by optical absorption spectroscopy measurements. The DSSCs built with the chlorophyll extracted by the proposed eco-protocol exhibit solar energy conversion efficiencies are similar to those obtained following extraction protocols with larger environmental impacts.

Edible seaweed as future functional food: Identification of α-glucosidase inhibitors by combined use of high-resolution α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR.

PubMed

Liu, Bingrui; Kongstad, Kenneth T; Wiese, Stefanie; Jäger, Anna K; Staerk, Dan

2016-07-15

Crude chloroform, ethanol and acetone extracts of nineteen seaweed species were screened for their antioxidant and α-glucosidase inhibitory activity. Samples showing more than 60% α-glucosidase inhibitory activity, at a concentration of 1 mg/ml, were furthermore investigated using high-resolution α-glucosidase inhibition profiling combined with high-performance liquid chromatography-high-resolution mass spectrometry-solid-phase extraction-nuclear magnetic resonance spectroscopy (HR-bioassay/HPLC-HRMS-SPE-NMR). The results showed Ascophyllum nodosum and Fucus vesicolosus to be rich in antioxidants, equaling a Trolox equivalent antioxidant capacity of 135 and 108 mM Troloxmg(-1) extract, respectively. HR-bioassay/HPLC-HRMS-SPE-NMR showed the α-glucosidase inhibitory activity of A. nodosum, F. vesoculosus, Laminaria digitata, Laminaria japonica and Undaria pinnatifida to be caused by phlorotannins as well as fatty acids - with oleic acid, linoleic acid and eicosapentaenoic acid being the most potent with IC50 values of 0.069, 0.075 and 0.10 mM, respectively, and showing a mixed-type inhibition mode. Copyright © 2016 Elsevier Ltd. All rights reserved.

Fucoxanthin Enhances Cisplatin-Induced Cytotoxicity via NFκB-Mediated Pathway and Downregulates DNA Repair Gene Expression in Human Hepatoma HepG2 Cells

PubMed Central

Liu, Cheng-Ling; Lim, Yun-Ping; Hu, Miao-Lin

2013-01-01

Cisplain, a platinum-containing anticancer drug, has been shown to enhance DNA repair and to inhibit cell apoptosis, leading to drug resistance. Thus, the combination of anticancer drugs with nutritional factors is a potential strategy for improving the efficacy of cisplatin chemotherapy. In this study, we investigated the anti-proliferative effects of a combination of fucoxanthin, the major non-provitamin A carotenoid found in Undaria Pinnatifida, and cisplatin in human hepatoma HepG2 cells. We found that fucoxanthin (1–10 μΜ) pretreatment for 24 h followed by cisplatin (10 μΜ) for 24 h significantly decreased cell proliferation, as compared with cisplatin treatment alone. Mechanistically, we showed that fucoxanthin attenuated cisplatin-induced NFκB expression and enhanced the NFκB-regulated Bax/Bcl-2 mRNA ratio. Cisplatin alone induced mRNA expression of excision repair cross complementation 1 (ERCC1) and thymidine phosphorylase (TP) through phosphorylation of ERK, p38 and PI3K/AKT pathways. However, fucoxanthin pretreatment significantly attenuated cisplatin-induced ERCC1 and TP mRNA expression, leading to improvement of chemotherapeutic efficacy of cisplatin. The results suggest that a combined treatment with fucoxanthin and cisplatin could lead to a potentially important new therapeutic strategy against human hepatoma cells. PMID:23299493

Effect of brown seaweed lipids on fatty acid composition and lipid hydroperoxide levels of mouse liver.

PubMed

Airanthi, M K Widjaja-Adhi; Sasaki, Naoya; Iwasaki, Sayaka; Baba, Nobuko; Abe, Masayuki; Hosokawa, Masashi; Miyashita, Kazuo

2011-04-27

Brown seaweed lipids from Undaria pinnatifida (Wakame), Sargassum horneri (Akamoku), and Cystoseira hakodatensis (Uganomoku) contained several bioactive compounds, namely, fucoxanthin, polyphenols, and omega-3 polyunsaturated fatty acids (PUFA). Fucoxanthin and polyphenol contents of Akamoku and Uganomoku lipids were higher than those of Wakame lipids, while Wakame lipids showed higher total omega-3 PUFA content than Akamoku and Uganomoku lipids. The levels of docosahexaenoic acid (DHA) and arachidonic acid (AA) in liver lipids of KK-A(y) mouse significantly increased by Akamoku and Uganomoku lipid feeding as compared with the control, but not by Wakame lipid feeding. Fucoxanthin has been reported to accelerate the bioconversion of omega-3 PUFA and omega-6 PUFA to DHA and AA, respectively. The higher hepatic DHA and AA level of mice fed Akamoku and Uganomoku lipids would be attributed to the higher content of fucoxanthin of Akamoku and Uganomoku lipids. The lipid hydroperoxide levels of the liver of mice fed brown seaweed lipids were significantly lower than those of control mice, even though total PUFA content was higher in the liver of mice fed brown seaweed lipids. This would be, at least in part, due to the antioxidant activity of fucoxanthin metabolites in the liver.

Understanding the association of Escherichia coli with diverse macroalgae in the lagoon of Venice

NASA Astrophysics Data System (ADS)

Quero, Grazia M.; Fasolato, Luca; Vignaroli, Carla; Luna, Gian Marco

2015-06-01

Recent studies provided evidence that the macroalga Cladopohora in lakes hosts associated Escherichia coli, with consequences on the environmental and human health. We expanded these investigations to other macroalgae (Ulva spp., Sargassum muticum and Undaria pinnatifida) widespread in the lagoon of Venice (Italy). Attached E. coli were abundant, accounting up to 3,250 CFU gram-1 of alga. Macroalgal-associated isolates belonged to all E. coli phylogroups, including pathogenic ones, and to Escherichia cryptic clades. Attached E. coli showed potential to grow even at in situ temperature on macroalgal extracts as only source of carbon and nutrients, and ability to produce biofilm in vitro. The genotypic diversity of the attached isolates was high, with significant differences between algae and the overlying water. Our evidences suggest that attached populations consist of both resident and transient strains, likely resulting from the heterogeneous input of fecal bacteria from the city. We report that cosmopolitan and invasive macroalgae may serve as source of E. coli, including pathogenic genotypes, and that this habitat can potentially support their growth. Considering the global diffusion of the macroalgae here studied, this phenomenon is likely occurring in other coastal cities worldwide and deserves further investigations from either the sanitary and ecological perspectives.

Understanding the association of Escherichia coli with diverse macroalgae in the lagoon of Venice

PubMed Central

Quero, Grazia M.; Fasolato, Luca; Vignaroli, Carla; Luna, Gian Marco

2015-01-01

Recent studies provided evidence that the macroalga Cladopohora in lakes hosts associated Escherichia coli, with consequences on the environmental and human health. We expanded these investigations to other macroalgae (Ulva spp., Sargassum muticum and Undaria pinnatifida) widespread in the lagoon of Venice (Italy). Attached E. coli were abundant, accounting up to 3,250 CFU gram−1 of alga. Macroalgal-associated isolates belonged to all E. coli phylogroups, including pathogenic ones, and to Escherichia cryptic clades. Attached E. coli showed potential to grow even at in situ temperature on macroalgal extracts as only source of carbon and nutrients, and ability to produce biofilm in vitro. The genotypic diversity of the attached isolates was high, with significant differences between algae and the overlying water. Our evidences suggest that attached populations consist of both resident and transient strains, likely resulting from the heterogeneous input of fecal bacteria from the city. We report that cosmopolitan and invasive macroalgae may serve as source of E. coli, including pathogenic genotypes, and that this habitat can potentially support their growth. Considering the global diffusion of the macroalgae here studied, this phenomenon is likely occurring in other coastal cities worldwide and deserves further investigations from either the sanitary and ecological perspectives. PMID:26043415

Understanding the association of Escherichia coli with diverse macroalgae in the lagoon of Venice.

PubMed

Quero, Grazia M; Fasolato, Luca; Vignaroli, Carla; Luna, Gian Marco

2015-06-04

Recent studies provided evidence that the macroalga Cladopohora in lakes hosts associated Escherichia coli, with consequences on the environmental and human health. We expanded these investigations to other macroalgae (Ulva spp., Sargassum muticum and Undaria pinnatifida) widespread in the lagoon of Venice (Italy). Attached E. coli were abundant, accounting up to 3,250 CFU gram(-1) of alga. Macroalgal-associated isolates belonged to all E. coli phylogroups, including pathogenic ones, and to Escherichia cryptic clades. Attached E. coli showed potential to grow even at in situ temperature on macroalgal extracts as only source of carbon and nutrients, and ability to produce biofilm in vitro. The genotypic diversity of the attached isolates was high, with significant differences between algae and the overlying water. Our evidences suggest that attached populations consist of both resident and transient strains, likely resulting from the heterogeneous input of fecal bacteria from the city. We report that cosmopolitan and invasive macroalgae may serve as source of E. coli, including pathogenic genotypes, and that this habitat can potentially support their growth. Considering the global diffusion of the macroalgae here studied, this phenomenon is likely occurring in other coastal cities worldwide and deserves further investigations from either the sanitary and ecological perspectives.

Promoting Wound Healing Using Low Molecular Weight Fucoidan in a Full-Thickness Dermal Excision Rat Model

PubMed Central

Park, Jun-Hyeong; Choi, Seong-Hun; Park, Soo-Jin; Lee, Young Joon; Park, Jong Hyun; Song, Phil Hyun; Cho, Chang-Mo; Ku, Sae-Kwang; Song, Chang-Hyun

2017-01-01

Low molecular weight fucoidan (LMF) has been reported to possess anti-inflammatory and antioxidant activities. Thus, we examined the effects of LMF extracted from Undaria pinnatifida on dermal wounds. Five round dermal wounds were created on the dorsal back of rats, and they were then treated topically with distilled water (DW), Madecasol Care™ (MC) or LMF at 200, 100 and 50 mg/mL, twice a day for a week. There were dose-dependent increases in wound contraction in the groups receiving LMF but not in the MC group, compared with the DW. Histopathological examination revealed that LMF treatment accelerated wound healing, which was supported by increases in granular tissue formation on day four post-treatment but a decrease on day seven, accompanied by an evident reduction in inflammatory cells. In the LMF-treated wounds, collagen distribution and angiogenesis were increased in the granular tissue on days four and seven post-treatment. Immunoreactive cells for transforming growth factor-β1, vascular endothelial growth factor receptor-2 or matrix metalloproteinases 9 were also increased, probably due to tissue remodeling. Furthermore, LMF treatment reduced lipid peroxidation and increased antioxidant activities. These suggested that LMF promotes dermal wound healing via complex and coordinated antioxidant, anti-inflammatory and growth factor-dependent activities. PMID:28387729

Crataegus pinnatifida: chemical constituents, pharmacology, and potential applications.

PubMed

Wu, Jiaqi; Peng, Wei; Qin, Rongxin; Zhou, Hong

2014-01-30

Crataegus pinnatifida (Hawthorn) is widely distributed in China and has a long history of use as a traditional medicine. The fruit of C. pinnatifida has been used for the treatment of cardiodynia, hernia, dyspepsia, postpartum blood stasis, and hemafecia and thus increasing interest in this plant has emerged in recent years. Between 1966 and 2013, numerous articles have been published on the chemical constituents, pharmacology or pharmacologic effects and toxicology of C. pinnatifida. To review the pharmacologic advances and to discuss the potential perspective for future investigation, we have summarized the main literature findings of these publications. So far, over 150 compounds including flavonoids, triterpenoids, steroids, monoterpenoids, sesquiterpenoids, lignans, hydroxycinnamic acids, organic acids and nitrogen-containing compounds have been isolated and identified from C. pinnatifida. It has been found that these constituents and extracts of C. pinnatifida have broad pharmacological effects with low toxicity on, for example, the cardiovascular, digestive, and endocrine systems, and pathogenic microorganisms, supporting the view that C. pinnatifida has favorable therapeutic effects. Thus, although C. pinnatifida has already been widely used as pharmacological therapy, due to its various active compounds, further research is warranted to develop new drugs.

Mekabu fucoidan: structural complexity and defensive effects against avian influenza A viruses.

PubMed

Synytsya, Andriy; Bleha, Roman; Synytsya, Alla; Pohl, Radek; Hayashi, Kyoko; Yoshinaga, Keiko; Nakano, Takahisa; Hayashi, Toshimitsu

2014-10-13

Fucoidan from the sporophyll (Mekabu) of brown seaweed Undaria pinnatifida (wakame) is interesting due to its various biological activities. Mekabu fucoidan (Mw ∼ 9 kDa) of this study (MF) was previously isolated and characterized by chemical and separation methods including GPC and methylation analysis (Lee, Hayashi, Hashimoto, Nakano, & Hayashi, 2004). It was found that this fucoidan composed of partially sulphated (DS ∼ 0.72) fucose and galactose at approximately equal amounts. Methylation analyses revealed complex structure of MF. However, it has been still unclear about the linkages between units and substitution patterns. To solve these structural tasks, spectroscopic methods (FTIR, FT Raman and NMR) were used in the analysis of native MF and its deesterified derivatives. According to obtained results, this polysaccharide was defined as O-acetylated sulphated fucogalactan. The defensive effects of MF were evaluated on mice infected with avian influenza A viruses (H5N3 and H7N2 subtypes); its efficacy was determined in reducing viral replication and increasing antibody production. Oral administration of MF resulted in suppressing virus yields. In addition, the production of neutralizing antibodies and mucosal IgA in the animals inoculated with the avian influenza A viruses was significantly increased. These results suggested that MF could be used for the prevention of viral infection. Copyright © 2014 Elsevier Ltd. All rights reserved.

The Edible Marine Alga Gracilariopsis chorda Alleviates Hypoxia/Reoxygenation-Induced Oxidative Stress in Cultured Hippocampal Neurons

PubMed Central

Mohibbullah, Md.; Hannan, Md. Abdul; Choi, Ji-Young; Bhuiyan, Mohammad Maqueshudul Haque; Hong, Yong-Ki; Choi, Jae-Suk; Choi, In Soon; Moon, Il Soo

2015-01-01

Abstract Age-related neurological disorders are of growing concern among the elderly, and natural products with neuroprotective properties have been attracting increasing attention as candidates for the prevention or treatment of neurological disorders induced by oxidative stress. In an effort to explore natural resources, we collected some common marine seaweed from the Korean peninsula and Indonesia and screened them for neuroprotective activity against hypoxia/reoxygenation (H/R)-induced oxidative stress. Of the 23 seaweeds examined, the ethanol extract of Gracilariopsis chorda (GCE) provided maximum neuroprotection at an optimum concentration of 15 μg/mL, followed by Undaria pinnatifida. GCE increased cell viability after H/R, decreased the formation of reactive oxygen species (measured by 2′,7′-dichlorodihydrofluorescein diacetate [DCF-DA] staining), and inhibited the double-stranded DNA breaks (measured by H2AX immunocytochemistry), apoptosis (measured by Annexin V/propidium iodide staining), internucleosomal DNA fragmentation (measured by DNA laddering), and dissipation of mitochondrial membrane potential (measured by JC-1 staining). Using reverse-phase high-pressure liquid chromatography, we quantitated the arachidonic acid (AA) in GCE, which provides neuroprotection against H/R-induced oxidative stress. This neuroprotective effect of AA was comparable to that of GCE. These findings suggest that the neuroprotective effect of GCE against H/R-induced neuronal death is due, at least in part, to the AA content that suppresses neuronal apoptosis. PMID:26106876

Protective effect of the edible brown alga Ecklonia stolonifera on doxorubicin-induced hepatotoxicity in primary rat hepatocytes.

PubMed

Jung, Hyun Ah; Kim, Jae-I; Choung, Se Young; Choi, Jae Sue

2014-08-01

As part of our efforts to isolate anti-hepatotoxic agents from marine natural products, we screened the ability of 14 edible varieties of Korean seaweed to protect against doxorubicin-induced hepatotoxicity in primary rat hepatocytes. Among the crude extracts of two Chlorophyta (Codium fragile and Capsosiphon fulvescens), seven Phaeophyta (Undaria pinnatifida, Sargassum thunbergii, Pelvetia siliquosa, Ishige okamurae, Ecklonia cava, Ecklonia stolonifera and Eisenia bicyclis), five Rhodophyta (Chondrus ocellatus, Gelidium amansii, Gracilaria verrucosa, Symphycladia latiuscula and Porphyra tenera), and the extracts of Ecklonia stolonifera, Ecklonia cava, Eisenia bicyclis and Pelvetia siliquosa exhibited significant protective effects on doxorubicin-induced hepatotoxicity, with half maximal effective concentration (EC50) values of 2.0, 2.5, 3.0 and 15.0 μg/ml, respectively. Since Ecklonia stolonifera exhibits a significant protective potential and is frequently used as foodstuff, we isolated six phlorotannins, including phloroglucinol (1), dioxinodehydroeckol (2), eckol (3), phlorofucofuroeckol A (4), dieckol (5) and triphloroethol-A (6). Phlorotannins 2 ∼ 6 exhibited potential protective effects on doxorubicin-induced hepatotoxicity, with corresponding EC50 values of 3.4, 8.3, 4.4, 5.5 and 11.5 μg/ml, respectively. The results clearly demonstrated that the anti-hepatotoxic effects of Ecklonia stolonifera and its isolated phlorotannins are useful for further exploration and development of therapeutic modalities for treatment of hepatotoxicity. © 2014 Royal Pharmaceutical Society.

Heavy metals in edible seaweeds commercialised for human consumption

NASA Astrophysics Data System (ADS)

Besada, Victoria; Andrade, José Manuel; Schultze, Fernando; González, Juan José

2009-01-01

Though seaweed consumption is growing steadily across Europe, relatively few studies have reported on the quantities of heavy metals they contain and/or their potential effects on the population's health. This study focuses on the first topic and analyses the concentrations of six typical heavy metals (Cd, Pb, Hg, Cu, Zn, total As and inorganic As) in 52 samples from 11 algae-based products commercialised in Spain for direct human consumption ( Gelidium spp.; Eisenia bicyclis; Himanthalia elongata; Hizikia fusiforme; Laminaria spp.; Ulva rigida; Chondrus crispus; Porphyra umbilicales and Undaria pinnatifida). Samples were ground, homogenised and quantified by atomic absorption spectrometry (Cu and Zn by flame AAS; Cd, Pb and total As by electrothermal AAS; total mercury by the cold vapour technique; and inorganic As by flame-hydride generation). Accuracy was assessed by participation in periodic QUASIMEME (Quality Assurance of Information in Marine Environmental Monitoring in Europe) and IAEA (International Atomic Energy Agency) intercalibration exercises. To detect any objective differences existing between the seaweeds' metal concentrations, univariate and multivariate studies (principal component analysis, cluster analysis and linear discriminant analysis) were performed. It is concluded that the Hizikia fusiforme samples contained the highest values of total and inorganic As and that most Cd concentrations exceeded the French Legislation. The two harvesting areas (Atlantic and Pacific oceans) were differentiated using both univariate studies (for Cu, total As, Hg and Zn) and a multivariate discriminant function (which includes Zn, Cu and Pb).

Hair growth activity of Crataegus pinnatifida on C57BL/6 mouse model.

PubMed

Shin, Heon-Sub; Lee, Jung-Min; Park, Sang-Yong; Yang, Jung-Eun; Kim, Ju-Han; Yi, Tae-Hoo

2013-09-01

Crataegus pinnatifida has a long history of use in traditional oriental herbal medicine to stimulating digestion and improving blood circulation. Based on nutrition of hair, the present study was conducted to assess the effect of C. pinnatifida extract on hair growth using mouse model and its mechanisms of action. The C. pinnatifida extract containing the contents of total polyphenol of 5.88□0.82 g gallic acid/100 g extract and proanthocyanidin of 9.15□1.58 mg cyaniding chloride/100 g extract was orally administered daily at a dosage of 50 mg/kg weight to the 7-week-old C57BL/6 mice in telogen. The C. pinnatifida extract promoted hair growth by inducing anagen phase in mice in telogen, reflected by color of skin, thickness of hair shaft, and density of hair. The ratio of anagento telogen was determined by shape of hair follicles in vertically sectioned slide and increased by oral administration of C. pinnatifida extract. The number and the size of hair follicles were also enlarged, indicating anagen phase induction. The proliferation of human dermal papilla cells (hDPC) was accelerated by addition of C. pinnatifida extract, which activated the signaling of mitogen-activated protein kinases (Erk, p-38, and JNK) and Akt. Moreover, the ratio of Bcl-2/Bax as the determinant of cell fate was also raised in skin. These results suggest that the C. pinnatifida extract promotes hair growth by inducing anagen phase, which might be mediated by the activation of cellular signalings that enhance the survival of cultured hDPC and the increase of the ratio of Bcl-2 to Bax that protects cells against cell death. Copyright © 2012 John Wiley & Sons, Ltd.

[Studies on evaluation of natural products for antiviral effects and their applications].

PubMed

Hayashi, Toshimitsu

2008-01-01

In the search for novel antiviral molecules from natural products, we have discovered various antiviral molecules with characteristic mechanisms of action. Scopadulciol (SDC), isolated from the tropical medicinal plant Scoparia dulcis L., showed stimulatory effects on the antiviral potency of acyclovir (ACV) or ganciclovir (GCV). This effect of SDC was exerted via the activation of viral thymidine kinase (HSV-1 TK) and, as a result, an increase in the cellular concentration of the active form of ACV/GCV, i.e., the triphosphate of ACV or GCV. On the basis of these experimental results, cancer gene therapy using the HSV-1 tk gene and ACV/GCV together with SDC was found to be effective in suppressing the growth of cancer cells in animals. Acidic polysaccharides such as calcium spirulan (Ca-SP) from Spirulina platensis, nostoflan from Nostoc flagelliforme, and a fucoidan from the sporophyll of Undaria pinnatifida (mekabu fucoidan) were also found to be potent inhibitors against several enveloped viruses. Their antiviral potency was dependent on molecular weight and content of the sulfate or carboxyl group as well as counterion species chelating with sulfate groups, indicating the importance of the three-dimensional structure of the molecules. In addition, unlike dextran sulfate, Ca-SP was shown to target not only viral absorption/penetration stages but also some replication stages of progeny viruses after penetration into cells. When mekabu fucoidan or nostoflan was administered with oseltamivir phosphate, their synergistic antiviral effects on influenza A virus were confirmed in vitro as well as in vivo.

Effect of Content of Sulfate Groups in Seaweed Polysaccharides on Antioxidant Activity and Repair Effect of Subcellular Organelles in Injured HK-2 Cells

PubMed Central

Ma, Xiao-Tao; Sun, Xin-Yuan; Yu, Kai; Gui, Qin

2017-01-01

This study aims to investigate the repair effect of subcellular structure injuries of the HK-2 cells of four degraded seaweed polysaccharides (DSPs), namely, the degraded Porphyra yezoensis, Gracilaria lemaneiformis, Sargassum fusiform, and Undaria pinnatifida polysaccharides. The four DSPs have similar molecular weight, but with different content of sulfate groups (i.e., 17.9%, 13.3%, 8.2%, and 5.5%, resp.). The damaged model was established using 2.8 mmol/L oxalate to injure HK-2 cells, and 60 μg/mL of various DSPs was used to repair the damaged cells. With the increase of sulfate group content in DSPs, the scavenging activity of radicals and their reducing power were all improved. Four kinds of DSPs have repair effect on the subcellular organelles of damaged HK-2 cells. After being repaired by DSPs, the release amount of lactate dehydrogenase was decreased, the integrity of cell membrane and lysosome increased, the Δψm increased, the cell of G1 phase arrest was inhibited, the proportion of S phase increased, and cell apoptotic and necrosis rates were significantly reduced. The greater the content of sulfate group is, the stronger is the repair ability of the polysaccharide. These DSPs, particularly the polysaccharide with higher sulfate group content, may be a potential drug for the prevention and cure of kidney stones. PMID:28785372

Prevention effect in selenite-induced cataract in vivo and antioxidative effects in vitro of Crataegus pinnatifida leaves.

PubMed

Wang, Tao; Zhang, Peng; Zhao, Chunfeng; Zhang, Yi; Liu, Hong; Hu, Limin; Gao, Xiumei; Zhang, Deqin

2011-07-01

Cataract is the leading cause of blindness worldwide. It is a multifactorial disease primarily associated with oxidative stress produced by free radicals. The present study was undertaken to evaluate the anticataract potential of Crataegus pinnatifida (hawthorn tree) leaves extract in selenite-induced cataract in vivo and antioxidant effects in vitro. In vitro antioxidant assay of C. pinnatifida leaves extract on NO production inhibition, aldose reductase inhibition, and O(2)(-) radical scavenging activities gave the IC(50) of 98.3, 89.7, and 5.98 μg/mL, respectively. To characterize some major compounds in C. pinnatifida leaves extract, nine flavonoids were identified via LC-MS/MS qualitative analysis. Based on in vitro screening results, C. pinnatifida leaves extract eye drops in 0.1% hydroxypropyl methyl cellulose solution were prepared to evaluate the anticataract potential in vivo. Administration of C. pinnatifida leaves extract eye drops alternately three times a day in rat pups with selenite-induced oxidative stress significantly increased serum SOD and CAT activities, and tended to reduce MDA level compared with control group. The antioxidant enzyme SOD, CAT, and GSH activities in lens showed a significant increase. These results may be applied in the future for the prevention and treatment of cataracts.

Development of new efficient method for isolation of phenolics from sea algae prior to their rapid resolution liquid chromatographic-tandem mass spectrometric determination.

PubMed

Klejdus, Bořivoj; Plaza, Merichel; Šnóblová, Marie; Lojková, Lea

2017-02-20

The extraction of phenolic compounds from 4 different sea algae samples, three brown algae (Cystoseira abies-marina, C. abies-marina grinded under cryogenic conditions with liquid nitrogen, Undaria pinnatifida and Sargassum muticum) and one red algae (Chondrus crispus) via solid phase extraction using micro-elution solid-phase extraction (μ-SPE) plate method was studied. Prior to μ-SPE, 50mg of algae with 80% methanol mixture was extracted in hyphenated series by various extraction techniques, such as pressurized liquid extraction and Ika Ultra-Turrax ® Tube Drive, in combination with ultrasound assisted extraction. The μ-SPE plate technique reduced the time of sample pre-treatment thanks to higher sensitivity and pre-concentration effect. Selected groups of benzoic acid derivatives (p-hydroxybenzoic, protocatechuic, gallic, vanillic, and syringic acids), hydroxybenzaldehydes (4-hydroxybenzaldehyde, and 3,4-dihydroxybenzaldehyde), and cinnamic acid derivatives (p-coumaric, caffeic, ferulic, sinapic, and chlorogenic acids) were determined using rapid resolution liquid chromatography coupled to mass spectrometry detection with negative ion electrospray ionization (RRLC-ESI-MS) using multiple reactions monitoring. LOQs of measured samples varied in the range 0.23-1.68ng/mL and LODs in the range 0.07-0.52ng/mL. The applied method allowed a simultaneous determination of phenolics (i.e. free, esters soluble in methanol, glycosides, and esters insoluble in methanol) in less than 5min (including alkaline or acidic hydrolysis of raw extracts) from sea algae extracts. Copyright © 2016 Elsevier B.V. All rights reserved.

A comprehensive approach to formulation of seaweed-enriched meat products: From technological development to assessment of healthy properties.

PubMed

Cofrades, S; Benedí, J; Garcimartin, A; Sánchez-Muniz, F J; Jimenez-Colmenero, F

2017-09-01

Meat consumption is influenced by various kinds of factors, among them health implications. Different strategies can be effective in developing meat-based functional foods. These basically entail reducing the presence of compounds with negative health implications and enhancing the presence of beneficial compounds. This article reviews a comprehensive model for the development of meat-based functional foods based on a presentation of the research achieved in terms of the design and development of qualitatively and quantitatively modified meat products (frankfurters, patties and restructured steaks). These were reformulated to incorporate nutrients associated with three different seaweeds (wakame-Undaria pinnatifida; nori-Porphyra umbilicalis; and sea spaghetti-Himanthalia elongata) as sources of bioactive substances, while simultaneously reducing sodium and fat and improving fatty acid profiles. Those seaweeds were chosen, because in terms of composition and health implications, abundance on Spanish coasts, relatively widespread consumption, and suitability in terms of flavour and colour they are better suited than others for use as ingredients in new products. It also discusses the consequences of the use of this type of meat-based functional foods (combination of pork meat and 5% of each seaweed with or without hypercholesterolaemic agent included in the diets) on growing animals (Wistar male rats), and their effects on different aspects of lipoprotein metabolism, oxidative stress and liver structure. This article, then, reports a comprehensive approach to the production of seaweed-enriched meat products, considering aspects of technological development aimed at achieving the functional effect. Copyright © 2016 Elsevier Ltd. All rights reserved.

Polyphenolic profile and biological activity of Chinese hawthorn (Crataegus pinnatifida BUNGE) fruits.

PubMed

Jurikova, Tunde; Sochor, Jiri; Rop, Otakar; Mlcek, Jiri; Balla, Stefan; Szekeres, Ladislav; Adam, Vojtech; Kizek, Rene

2012-12-06

Chinese hawthorn (Crataegus pinnatifida Bge.) fruits are rich in polyphenols (e.g., epicatechin, procyanidin B2, procyanidin B5, procyanidin C1, hyperoside, isoquercitrin and chlorogenic acid)--active compounds that exert beneficial effects. This review summarizes all information available on polyphenolic content and methods for their quantification in Chinese hawthorn berries and the relationships between individual polyphenolic compounds as well. The influence of species or cultivars, the locality of cultivation, the stage of maturity, and extract preparation conditions on the polyphenolic content were discussed as well. Currently, only fruits of C. pinnatifida and C. pinnatifida var. major are included in the Chinese Pharmacopoeia. Recent trials have demonstrated the efficacy of Chinese hawthorn fruit in lowering blood cholesterol and the risk of cardiovascular diseases. The fruit has also demonstrated anti-inflammatory and anti-tumour activities. This review deals mainly with the biological activity of the fruit related to its antioxidant properties.

[Comparison of morphological and microscopical diagnostic characters of Hawthorn fruits (Crataegus species)].

PubMed

Gao, G Y; Feng, Y X

1995-01-01

This paper deals with studies on morphological and microscopical diagnostic characters of Chinese Hawthorn fruits. Their similarities and differences in morphological and microscopical characters among eight species of Crataegus (C. pinnatifida Bge., C. pinnatifida var. major NE Br., C. cuneata sieb. & Zuce., C. scabrifolia (Franch.) Rehd., C. hupehensis Sarg., C. kansuensis Wils, C. maximowiczii Schneid. and C. sanguinea Pall.) fruits are compared and illustrated with diagrams.

Conservation systematics of the shield-backed trapdoor spiders of the nigrum-group (Mygalomorphae, Idiopidae, Idiosoma): integrative taxonomy reveals a diverse and threatened fauna from south-western Australia.

PubMed

Rix, Michael G; Huey, Joel A; Cooper, Steven J B; Austin, Andrew D; Harvey, Mark S

2018-01-01

The aganippine shield-backed trapdoor spiders of the monophyletic nigrum -group of Idiosoma Ausserer s. l. are revised, and 15 new species are described from Western Australia and the Eyre Peninsula of South Australia: I. arenaceum Rix & Harvey, sp. n. , I. corrugatum Rix & Harvey, sp. n. , I. clypeatum Rix & Harvey, sp. n. , I. dandaragan Rix & Harvey, sp. n. , I. formosum Rix & Harvey, sp. n. , I. gardneri Rix & Harvey, sp. n. , I. gutharuka Rix & Harvey, sp. n. , I. incomptum Rix & Harvey, sp. n. , I. intermedium Rix & Harvey, sp. n. , I. jarrah Rix & Harvey, sp. n. , I. kopejtkaorum Rix & Harvey, sp. n. , I. kwongan Rix & Harvey, sp. n. , I. mcclementsorum Rix & Harvey, sp. n. , I. mcnamarai Rix & Harvey, sp. n. , and I. schoknechtorum Rix & Harvey, sp. n. Two previously described species from south-western Western Australia, I. nigrum Main, 1952 and I. sigillatum (O. P.-Cambridge, 1870), are re-illustrated and re-diagnosed, and complementary molecular data for 14 species and seven genes are analysed with Bayesian methods. Members of the nigrum -group are of long-standing conservation significance, and I. nigrum is the only spider in Australia to be afforded threatened species status under both State and Commonwealth legislation. Two other species, I. formosum Rix & Harvey, sp. n. and I. kopejtkaorum Rix & Harvey, sp. n. , are also formally listed as Endangered under Western Australian State legislation. Here we significantly relimit I. nigrum to include only those populations from the central and central-western Wheatbelt bioregion, and further document the known diversity and conservation status of all known species.

Conservation systematics of the shield-backed trapdoor spiders of the nigrum-group (Mygalomorphae, Idiopidae, Idiosoma): integrative taxonomy reveals a diverse and threatened fauna from south-western Australia

PubMed Central

Rix, Michael G.; Huey, Joel A.; Cooper, Steven J.B.; Austin, Andrew D.; Harvey, Mark S.

2018-01-01

Abstract The aganippine shield-backed trapdoor spiders of the monophyletic nigrum-group of Idiosoma Ausserer s. l. are revised, and 15 new species are described from Western Australia and the Eyre Peninsula of South Australia: I. arenaceum Rix & Harvey, sp. n., I. corrugatum Rix & Harvey, sp. n., I. clypeatum Rix & Harvey, sp. n., I. dandaragan Rix & Harvey, sp. n., I. formosum Rix & Harvey, sp. n., I. gardneri Rix & Harvey, sp. n., I. gutharuka Rix & Harvey, sp. n., I. incomptum Rix & Harvey, sp. n., I. intermedium Rix & Harvey, sp. n., I. jarrah Rix & Harvey, sp. n., I. kopejtkaorum Rix & Harvey, sp. n., I. kwongan Rix & Harvey, sp. n., I. mcclementsorum Rix & Harvey, sp. n., I. mcnamarai Rix & Harvey, sp. n., and I. schoknechtorum Rix & Harvey, sp. n. Two previously described species from south-western Western Australia, I. nigrum Main, 1952 and I. sigillatum (O. P.-Cambridge, 1870), are re-illustrated and re-diagnosed, and complementary molecular data for 14 species and seven genes are analysed with Bayesian methods. Members of the nigrum-group are of long-standing conservation significance, and I. nigrum is the only spider in Australia to be afforded threatened species status under both State and Commonwealth legislation. Two other species, I. formosum Rix & Harvey, sp. n. and I. kopejtkaorum Rix & Harvey, sp. n., are also formally listed as Endangered under Western Australian State legislation. Here we significantly relimit I. nigrum to include only those populations from the central and central-western Wheatbelt bioregion, and further document the known diversity and conservation status of all known species. PMID:29773959

Phenolic contents and cellular antioxidant activity of Chinese hawthorn "Crataegus pinnatifida".

PubMed

Wen, Lingrong; Guo, Xingbo; Liu, Rui Hai; You, Lijun; Abbasi, Arshad Mehmood; Fu, Xiong

2015-11-01

It is evident from various epidemiological studies that consumption of fruits and vegetables is essential to maintain health and in the disease prevention. Present study was designed to examine phenolic contents and antioxidant properties of three varieties of Crataegus pinnatifida (Chinese hawthorn). Shanlihong variety exhibited elevated levels of total phenolics and flavonoid contents, including free and bond phenolics. Procyanidin B2 was most abundant phenolic compound in all samples, followed by epicatechin, chlorogenic acid, hyperoside, and isoquercitrin. The free ORAC values, and free hydro-PSC values were 398.3-555.8 μmol TE/g DW, and 299.1-370.9 μmol VCE/g DW, respectively. Moreover, the free cellular antioxidant activity (CAA) values were 678-1200 μmol of QE/100 g DW in the no PBS wash protocol, and 345.9-532.9 μmol of QE/100 g DW in the PBS wash protocol. C. pinnatifida fruit could be valuable to promote consumer health. Copyright © 2015 Elsevier Ltd. All rights reserved.

Chemically-mediated interactions between macroalgae Dictyota spp. and multiple life-history stages of the coral Porites astreoides

USGS Publications Warehouse

Paul, Valerie J.; Kuffner, Ilsa B.; Walters, Linda J.; Ritson-Williams, Raphael; Beach, Kevin S.; Becerro, Mikel A.

2011-01-01

Competition between corals and macroalgae is often assumed to occur on reefs, especially those that have undergone shifts from coral to algal dominance; however, data examining these competitive interactions, especially during the early life-history stages of corals, are scarce. We conducted a series of field and outdoor seawater-table experiments to test the hypothesis that allelopathy (chemical inhibition) mediates interactions between 2 common brown macroalgae, Dictyota pulchella and D. pinnatifida, and the coral Porites astreoides at different life-history stages of the coral. D. pinnatifida significantly reduced larval survival and larval recruitment. The extracts of both D. pinnatifida and D. pulchella significantly reduced larval survival, and the extract of D. pulchella also negatively influenced larval recruitment. There was no measurable effect of the crude extracts from Dictyota spp. on the photophysiology of adult corals. Our results provide evidence that these Dictyota species chemically compete with P. astreoides by negatively affecting larval settlement and recruitment as well as the survival of larvae and new recruits. Macroalgae may perpetuate their dominance on degraded reefs by chemically inhibiting the process of coral recruitment.

Blood money: Harvey's De motu cordis (1628) as an exercise in accounting.

PubMed

Neuss, Michael J

2018-04-13

William Harvey's famous quantitative argument from De motu cordis (1628) about the circulation of blood explained how a small amount of blood could recirculate and nourish the entire body, upending the Galenic conception of the blood's motion. This paper argues that the quantitative argument drew on the calculative and rhetorical skills of merchants, including Harvey's own brothers. Modern translations of De motu cordis obscure the language of accountancy that Harvey himself used. Like a merchant accounting for credits and debits, intake and output, goods and moneys, Harvey treated venous and arterial blood as essentially commensurate, quantifiable and fungible. For Harvey, the circulation (and recirculation) of blood was an arithmetical necessity. The development of Harvey's circulatory model followed shifts in the epistemic value of mercantile forms of knowledge, including accounting and arithmetic, also drawing on an Aristotelian language of reciprocity and balance that Harvey shared with mercantile advisers to the royal court. This paper places Harvey's calculations in a previously underappreciated context of economic crisis, whose debates focused largely on questions of circulation.

76 FR 70345 - Drawbridge Operation Regulation; Gulf Intracoastal Waterway, LA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-14

... span drawbridge across the Harvey Canal Route, Gulf Intracoastal Waterway (GIWW), mile 2.8 at Harvey... Harvey Canal Route, Intracoastal Waterway, mile 2.8 at Harvey, Jefferson Parish, Louisiana. The bridge... 117.451(a). The closure is necessary in order to clean and repaint the steel surfaces of the bridge...

William Harvey, Aristotle and astrology.

PubMed

Gregory, Andrew

2014-06-01

In this paper I argue that William Harvey believed in a form of astrology. It has long been known that Harvey employed a macrocosm-microcosm analogy and used alchemical terminology in describing how the two types of blood change into one another. This paper then seeks to examine a further aspect of Harvey in relation to the magical tradition. There is an important corollary to this line of thought, however. This is that while Harvey does have a belief in astrology, it is strongly related to Aristotle's views in this area and is quite restricted and attenuated relative to some contemporary beliefs in astrology. This suggests a more general thesis. While Harvey was amenable to ideas which we associate with the natural magic tradition, those ideas had a very broad range of formulation and there was a limit to how far he would accept them. This limit was largely determined by Harvey's adherence to Aristotle's natural philosophy and his Christian beliefs. I argue that this is also the case in relation to Harvey's use of the macrocosm-microcosm analogy and of alchemical terminology, and, as far as we can rely on the evidence, this informs his attitudes towards witches as well. Understanding Harvey's influences and motives here is important in placing him properly in the context of early seventeenth-century thought.

Chemically mediated interactions between macroalgae Dictyota spp. and multiple life-history stages of the coral Porites astreoides

USGS Publications Warehouse

Paul, V.J.; Kuffner, I.B.; Walters, L.J.; Ritson-Williams, R.; Beach, K.S.; Becerro, M.A.

2011-01-01

Competition between corals and macroalgae is often assumed to occur on reefs, especially those that have undergone shifts from coral to algal dominance; however, data examining these competitive interactions, especially during the early life-history stages of corals, are scarce. We conducted a series of field and outdoor seawater-table experiments to test the hypothesis that allelopathy (chemical inhibition) mediates interactions between 2 common brown macroalgae, Dictyota pulchella and D. pinnatifida, and the coral Porites astreoides at different life-history stages of the coral. D. pinnatifida significantly reduced larval survival and larval recruitment. The extracts of both D. pinnatifida and D. pulchella significantly reduced larval survival, and the extract of D. pulchella also negatively influenced larval recruitment. There was no measurable effect of the crude extracts from Dictyota spp. on the photophysiology of adult corals. Our results provide evidence that these Dictyota species chemically compete with P. astreoides by negatively affecting larval settlement and recruitment as well as the survival of larvae and new recruits. Macroalgae may perpetuate their dominance on degraded reefs by chemically inhibiting the process of coral recruitment. ?? 2011 Inter-Research.

Acids, sugars, and sugar alcohols in Chinese hawthorn (Crataegus spp.) fruits.

PubMed

Liu, Pengzhan; Kallio, Heikki; Lü, Deguo; Zhou, Chuansheng; Ou, Shiyi; Yang, Baoru

2010-01-27

Acids, sugars, and sugar alcohols in the fruits of 22 cultivars/origins of three species of hawthorn (Crataegus spp.) were analyzed by gas chromatography and mass spectrometry. Citric acid (2.0-8.4 g/100 g dry mass [DM]), quinic acid (0.5-5.6 g/100 g DM), malic acid (0.3-1.1 g/100 g DM), fructose (5.5-18.4 g/100 g DM), glucose (5.3-16.6 g/100 g DM), sorbitol (3.0-15.7 g/100 g DM), and myo-inositol (0.1-0.3 g/100 g DM) were found in all the samples. Sucrose was present only in C. scabrifolia and three cultivars of C. pinnatifida var. major. C. scabrifolia differed from other species by its high content of quinic acid. The cultivars of C. pinnatifida var. major and C. brettschneideri had a higher content of total sugars and a higher sugar/acid ratio than the natural origins of C. pinnatifida and C. scabrifolia (P < 0.05). The hawthorn samples analyzed fell into two groups rich in sugars and acids respectively. This is the first report of the profiles of sugars and sugar alcohols and the occurrence of quinic acid in hawthorn fruits.

Polyunsaturated fatty acids in various macroalgal species from North Atlantic and tropical seas.

PubMed

van Ginneken, Vincent J T; Helsper, Johannes P F G; de Visser, Willem; van Keulen, Herman; Brandenburg, Willem A

2011-06-22

In this study the efficacy of using marine macroalgae as a source for polyunsaturated fatty acids, which are associated with the prevention of inflammation, cardiovascular diseases and mental disorders, was investigated. The fatty acid (FA) composition in lipids from seven sea weed species from the North Sea (Ulva lactuca, Chondrus crispus, Laminaria hyperborea, Fucus serratus, Undaria pinnatifida, Palmaria palmata, Ascophyllum nodosum) and two from tropical seas (Caulerpa taxifolia, Sargassum natans) was determined using GCMS. Four independent replicates were taken from each seaweed species. Omega-3 (n-3) and omega-6 (n-6) polyunsaturated fatty acids (PUFAs), were in the concentration range of 2-14 mg/g dry matter (DM), while total lipid content ranged from 7-45 mg/g DM. The n-9 FAs of the selected seaweeds accounted for 3%-56% of total FAs, n-6 FAs for 3%-32% and n-3 FAs for 8%-63%. Red and brown seaweeds contain arachidonic (C20:4, n-6) and/or eicosapentaenoic acids (EPA, C20:5, n-3), the latter being an important "fish" FA, as major PUFAs while in green seaweeds these values are low and mainly C16 FAs were found. A unique observation is the presence of another typical "fish" fatty acid, docosahexaenoic acid (DHA, C22:6, n-3) at ≈ 1 mg/g DM in S. natans. The n-6: n-3 ratio is in the range of 0.05-2.75 and in most cases below 1.0. Environmental effects on lipid-bound FA composition in seaweed species are discussed. Marine macroalgae form a good, durable and virtually inexhaustible source for polyunsaturated fatty acids with an (n-6) FA: (n-3) FA ratio of about 1.0. This ratio is recommended by the World Health Organization to be less than 10 in order to prevent inflammatory, cardiovascular and nervous system disorders. Some marine macroalgal species, like P. palmata, contain high proportions of the "fish fatty acid" eicosapentaenoic acid (EPA, C20:5, n-3), while in S. natans also docosahexaenoic acid (DHA, C22:6, n-3) was detected.

Polyunsaturated fatty acids in various macroalgal species from north Atlantic and tropical seas

PubMed Central

2011-01-01

Background In this study the efficacy of using marine macroalgae as a source for polyunsaturated fatty acids, which are associated with the prevention of inflammation, cardiovascular diseases and mental disorders, was investigated. Methods The fatty acid (FA) composition in lipids from seven sea weed species from the North Sea (Ulva lactuca, Chondrus crispus, Laminaria hyperborea, Fucus serratus, Undaria pinnatifida, Palmaria palmata, Ascophyllum nodosum) and two from tropical seas (Caulerpa taxifolia, Sargassum natans) was determined using GCMS. Four independent replicates were taken from each seaweed species. Results Omega-3 (n-3) and omega-6 (n-6) polyunsaturated fatty acids (PUFAs), were in the concentration range of 2-14 mg/g dry matter (DM), while total lipid content ranged from 7-45 mg/g DM. The n-9 FAs of the selected seaweeds accounted for 3%-56% of total FAs, n-6 FAs for 3%-32% and n-3 FAs for 8%-63%. Red and brown seaweeds contain arachidonic (C20:4, n-6) and/or eicosapentaenoic acids (EPA, C20:5, n-3), the latter being an important "fish" FA, as major PUFAs while in green seaweeds these values are low and mainly C16 FAs were found. A unique observation is the presence of another typical "fish" fatty acid, docosahexaenoic acid (DHA, C22:6, n-3) at ≈ 1 mg/g DM in S. natans. The n-6: n-3 ratio is in the range of 0.05-2.75 and in most cases below 1.0. Environmental effects on lipid-bound FA composition in seaweed species are discussed. Conclusion Marine macroalgae form a good, durable and virtually inexhaustible source for polyunsaturated fatty acids with an (n-6) FA: (n-3) FA ratio of about 1.0. This ratio is recommended by the World Health Organization to be less than 10 in order to prevent inflammatory, cardiovascular and nervous system disorders. Some marine macroalgal species, like P. palmata, contain high proportions of the "fish fatty acid" eicosapentaenoic acid (EPA, C20:5, n-3), while in S. natans also docosahexaenoic acid (DHA, C22:6, n-3) was detected. PMID:21696609

Inhibitory effect of hot-water extract from dried fruit of Crataegus pinnatifida on low-density lipoprotein (LDL) oxidation in cell and cell-free systems.

PubMed

Chu, Chia-Yih; Lee, Miao-Jane; Liao, Chuen-Lan; Lin, Wea-Lung; Yin, Yu-Fang; Tseng, Tsui-Hwa

2003-12-17

The dried fruit of Crataegus pinnatifida, a local soft drink material and medical herb, was found to possess potential against oxidative stress. In the preliminary study, the antioxidant potential of a hot-water extract obtained from the dried fruit of C. pinnatifida (CF-H) was evaluated in terms of its capacity of quenching 1,1-diphenyl-2-picrylhydrazyl free radicals (EC(50) = 0.118 mg/mL). After content analysis, it was found that CF-H is mainly composed of polyphenols including flavonoids (6.9%), procyanidins (2.2%), (+)-catechin (0.5%), and (-)-epicatechin (0.2%). The antioxidative bioactivity of CF-H had been assess previously using the models of CuSO(4) as cell-free system and sodium nitroprusside (SNP) plus macrophage RAW 264.7 cells as cell system to induce human low-density lipoprotein oxidation. CF-H was found to inhibit relative electrophoretic mobility and thiobarbituric acid reactive substances at the concentration of 0.5-1.0 mg/mL in the cell-free system and at 0.01-0.10 mg/mL in the cell system. Furthermore, it was found that CF-H decreased the SNP-induced cell lipid peroxidation and reduced glutathione depletion.

33 CFR 165.T08-0434 - Safety Zone; Mile Marker 98.5 West of Harvey Lock Gulf Intracoastal Waterway to Mile Marker 108.5...

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Safety Zone; Mile Marker 98.5 West of Harvey Lock Gulf Intracoastal Waterway to Mile Marker 108.5 West of Harvey Lock Gulf... § 165.T08-0434 Safety Zone; Mile Marker 98.5 West of Harvey Lock Gulf Intracoastal Waterway to Mile...

West Bank of the Mississippi River in the Vicinity of New Orleans, LA (East of the Harvey Canal)

DTIC Science & Technology

1994-08-01

bicycle transportation corridors could be approved by the local levee board, state bicycle coordinators, and metropolitan planning organizations. 34 I_...the east side of the Harvey Canal. The area from just east of Peters Road to the Harvey Canal is an industrial corridor . The industries within this... corridor require access to the Harvey Canal. These industries have strongly opposed any alignment that would affect their access to the canal. Severe

Hurricane Harvey - Aug. 24, 2017

NASA Image and Video Library

2017-08-24

The International Space Station’s external cameras captured a dramatic view of Hurricane Harvey as it bore down on the central Texas coast Aug. 24. The National Hurricane Center predicts a landfall for Harvey near Corpus Christi, Texas early Aug. 26 with potentially record floods expected along the Texas coastline through next week.

Major triterpenoids in Chinese hawthorn "Crataegus pinnatifida" and their effects on cell proliferation and apoptosis induction in MDA-MB-231 cancer cells.

PubMed

Wen, Lingrong; Guo, Ruixue; You, Lijun; Abbasi, Arshad Mehmood; Li, Tong; Fu, Xiong; Liu, Rui Hai

2017-02-01

The cytotoxicity and antiproliferative effect of phytochemicals presenting in the fruits of Chinese hawthorn (Crataegus pinnatifida) were evaluated. Shanlihong (Crataegus pinnatifida Bge. var. major N.E.Br.) variety possessed significant levels of flavonoids and triterpenoids, and showed potent antiproliferative effect against HepG 2 , MCF-7 and MDA-MB- 231 human cancer cells lines. Triterpenoids-enriched fraction (S9) prepared by Semi-preparative HPLC, and its predominant ingredient ursolic acid (UA) demonstrated remarkably antiproliferative activities for all the tested cancer cell lines. DNA flow cytometric analysis showed that S9 fraction and UA significantly induced G1 arrest in MDA-MB-231 cells in a dose-dependent manner. Western blotting analysis revealed that S9 fraction and UA significantly induced PCNA, CDK4, and Cyclin D1 downregulation in MDA-MB-231 cells, followed by p21 Waf1/Cip1 up-regulation. Additionally, flow cytometer and DNA ladder assays indicated that S9 fraction and UA significantly induced MDA-MB-231 cells apoptosis. Mitochondrial death pathway was involved in this apoptosis as significantly induced caspase-9 and caspase-3 activation. These results suggested that triterpenoids-enriched fraction and UA exhibited antiproliferative activity through the cell cycle arrest and apoptosis induction, and was majorly responsible for the potent anticancer activity of Chinese hawthorn. Copyright © 2016 Elsevier Ltd. All rights reserved.

Food Byproducts as a New and Cheap Source of Bioactive Compounds: Lignans with Antioxidant and Anti-inflammatory Properties from Crataegus pinnatifida Seeds.

PubMed

Huang, Xiao-Xiao; Bai, Ming; Zhou, Le; Lou, Li-Li; Liu, Qing-Bo; Zhang, Yan; Li, Ling-Zhi; Song, Shao-Jiang

2015-08-19

During the process of manufacturing hawthorn (Crataegus pinnatifida) juice and jam, a significant quantity of byproducts (leaves, seeds) is generated. The antioxidant and anti-inflammatory bioassay-guided fractionation of the extract of hawthorn seeds has led to the isolation of eight new lignans, hawthornnins A-H (1-8), and seven known analogues (9-15). Their structures were elucidated by spectroscopic techniques, including 1D and 2D NMR and CD spectra. The radical-scavenging effects of all isolated compounds were investigated. 1-6 and 8 showed moderate activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH), whereas 1-6 and 14 displayed good 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) free radical-scavenging activities that were even more potent than that of trolox. In addition, all isolates were evaluated for their anti-inflammatory activities by detecting the nitric oxide (NO) and tumor necrosis factor α (TNF-α) production by the LPS-induced murine macrophage cell line RAW264.7, and compounds 1-7, 13, and 14 exhibited potent inhibition of NO and TNF-α production. The structure-activity relationships of isolated lignans were also examined, and the results obtained show that C. pinnatifida seeds can be regarded as a potential new and cheap source of antioxidants and inflammation inhibitors.

[Reconsideration of the "conversion theory" from the primacy of the heart to the primacy of the blood--William Harvey's observation, logic and the construction of the exercitatio].

PubMed

Tsukisawa, M

1995-01-01

In De Motu Cordis, W. Harvey sometimes waxes lyrical on the primacy of the heart. In his another treatise, De Generatione, however, he insists on the primacy of the blood. The "conversion theory" explained this discrepancy with Harvey's conversion as caused by his discovery of the antiquity of the blood. But Whitterridge showed that Harvey had already described the antiquity of the blood in his earliest notebook, Prelectiones. As shown in this article, Harvey's observation was not a mere accidental discovery; based on the "classic questions", it was continuously and persistently conducted until he was assured of having seen the blood to exist prior to the pulse and movement to occur in the blood. While this crucial observation was not yet made in Prelectiones and De Motu Cordis, it was described as crucial evidence of the theory of the primacy of the blood in De Generatione, in which this new theory was introduced as an independent topic of the exercitatio. The topic of the order of the generation was a crucial issue in the theoretical medicine of Harvey's days. That is, the Aristotelian primacy of the heart had been seriously challenged by the Galenic tripartite theory which pursued the antiquity of three organs. Harvey's theory, or the primacy of the blood, seems to consists with Aristotle's premise, in that it asserts the existence of the only source of all functions in living animals. Harvey's theory, however, was confronted, on the other hand, with Aristotle's another inconsistency, namely, the issue of two definitions about anima. We must consider the construction and strategy of the exercitatio in Harvey's days to understand the exact meaning of the primacy of the heart in De Motu Cordis. In De Motu Cordis, Harvey did not use the primacy of the heart in a central part of the exercitatio, namely, in confirming his unprecedented theory, the circulation of the blood, but he settled this Aristotelian premise in a marginal part, namely, in ratiocinating the final cause of the circulation and supporting his new theory from the sidelines.

[Reconsideration of the "conversion theory" from the primacy of the heart to the primacy of the blood--William Harvey's observation, logic and the construction of the exercitatio].

PubMed

Tsukisawa, M

1995-01-01

In De motu cordis, W. Harvey sometimes waxes lyrical on the primacy of the heart. In his another treatise, De generatione, however, he insists on the primacy of the blood. The "conversion theory" explained this discrepancy with Harvey's conversion as caused by his discovery of the antiquity of the blood. But Whitterridge showed that Harvey had already described the antiquity of the blood in his earliest notebook, Prelectiones. As shown in this article, Harvey's observation was not a mere accidental discovery; based on the "classic questions", it was continuously and persistently conducted until he was assured of having seen the blood to exist prior to the pulse and movement to occur in the blood. While this crucial observation was not yet made in Prelectiones and De motu cordis, it was described as crucial evidence of the theory of the primacy of the blood in De generatione, in which this new theory was introduced as an independent topic of the exercitatio. The topic of the order of the generation was a crucial issue in the theoretical medicine of Harvey's days. That is, the Aristotelian primacy of the heart had been seriously challenged by the Galenic tripartite theory which pursued the antiquity of three organs. Harvey's theory, or the primacy of the blood, seems to consists with Aristotle's premise, in that it asserts the existance of the only source of all functions in living animals. Harvey's theory, however, was confronted, on the other hand, with Aristotle's another inconsistency, namely, the issue of two definitions about anima. We must consider the construction and strategy of the exercitatio in Harvey's days to understand the exact meaning of the primacy of the heart in De motu cordis. In De motu cordis, Harvey did not use the primacy of the heart in a central part of the exercitatio, namely, in confirming his unprecedented theory, the circulation of the blood, but he settled this Aristotelian premise in a marginal part, namely, in ratiocinating the final cause of the circulation and supporting his new theory from the sidelines.

1. Photocopy of measured drawing (from: Harvey, Robert R. 'Historic ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Photocopy of measured drawing (from: Harvey, Robert R. 'Historic Stone Architecture of Winterset, Iowa, Prior to and During the Civil War Period.' Ames, IA: Iowa State University, 1960) Robert R. Harvey, delineator 1960 FLOOR PLAN, ORIGINAL HOUSE ('FIGURE 3-A') - Caleb Clark House, 814 South Eighth Street, Winterset, Madison County, IA

Contrasting Hydrodynamic and Environmental Effects of Hurricanes Harvey and Ike in a Highly Industrialized Estuary

NASA Astrophysics Data System (ADS)

Kiaghadi, A.; Rifai, H. S.

2017-12-01

It is commonly believed that storm surge is the most destructive aspect of hurricanes. However, massive rainfall with a return period of 100 years or more induced by hurricanes can cause more catastrophic damage than losses caused by storm surge as demonstrated recently by hurricanes Harvey, Irma and Maria. In this study the hydrodynamics and environmental effects of hurricanes Ike and Harvey were compared and contrasted by linking hydrodynamic flow models with water quality models to simulate spills from storage tanks located in the Houston Ship Channel (HSC). Hurricane Ike with a maximum surge of 5.3 meters in Galveston Bay and Harvey with a maximum rainfall of 1.25 meters both struck the HSC region in Texas in 2008 and 2017, respectively. Both events resulted in numerous spills from municipal and industrial facilities, hazardous waste sites, superfund sites, and landfills. The Environmental Fluid Dynamic Code (EFDC) was coupled with the SWAN+ADCIRC hurricane simulation model to simulate Hurricane Ike and EFDC was coupled with USGS flow boundary conditions to model Hurricane Harvey. A conservative dye release was used to simulate a chemical release during each event. The results showed Hurricane Harvey caused higher water surface elevations within the HSC accompanied by longer and wider-spread land inundation. In contrast, higher water surface elevations were observed within the shallow side bays during Hurricane Ike that caused sediment resuspension and repartitioning of pollutants. Rapid spill mass transportation was observed for both hurricanes; 50% of total spill mass reached Galveston Bay in 20 and 22 hours after a spill event for Hurricane Harvey and Ike, respectively, and more than 90% of the spill mass reached the bay in 36 and 48 hours, respectively. Unlike Hurricane Harvey, the conservative tracer was spread almost 2.5 km upstream of the releasing point for Hurricane Ike due to surge. However, during Harvey, 35% more land was affected by the spilled mass with five times more remained mass on the land.

3. Photocopy of measured drawing (from: Harvey, Robert R. 'Historic ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Photocopy of measured drawing (from: Harvey, Robert R. 'Historic Stone Architecture of Winterset, Iowa, Prior to and During the Civil War Period.' Ames, IA: Iowa State University, 1960.) Robert R. Harvey, delineator 1960 FLOOR PLAN, ORIGINAL HOUSE PLUS SMOKEHOUSE ADDITION ('FIGURE 3-C') - Caleb Clark House, 814 South Eighth Street, Winterset, Madison County, IA

2. Photocopy of measured drawing (from: Harvey, Robert R. 'Historic ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Photocopy of measured drawing (from: Harvey, Robert R. 'Historic Stone Architecture of Winterset, Iowa, Prior to and During the Civil War Period.' Ames, IA: Iowa State University, 1960.) Robert R. Harvey, delineator 1960 FLOOR PLAN, ORIGINAL HOUSE PLUS WELLHOUSE ADDITION ('FIGURE 3-B') - Caleb Clark House, 814 South Eighth Street, Winterset, Madison County, IA

33 CFR 334.412 - Albemarle Sound, Pamlico Sound, Harvey Point and adjacent waters, NC; restricted area.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Albemarle Sound, Pamlico Sound... REGULATIONS § 334.412 Albemarle Sound, Pamlico Sound, Harvey Point and adjacent waters, NC; restricted area. (a) The area. Beginning on the north shore of Albemarle Sound and the easternmost tip of Harvey Point...

33 CFR 334.412 - Albemarle Sound, Pamlico Sound, Harvey Point and adjacent waters, NC; restricted area.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Albemarle Sound, Pamlico Sound... REGULATIONS § 334.412 Albemarle Sound, Pamlico Sound, Harvey Point and adjacent waters, NC; restricted area. (a) The area. Beginning on the north shore of Albemarle Sound and the easternmost tip of Harvey Point...

33 CFR 334.412 - Albemarle Sound, Pamlico Sound, Harvey Point and adjacent waters, NC; restricted area.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Albemarle Sound, Pamlico Sound... REGULATIONS § 334.412 Albemarle Sound, Pamlico Sound, Harvey Point and adjacent waters, NC; restricted area. (a) The area. Beginning on the north shore of Albemarle Sound and the easternmost tip of Harvey Point...

33 CFR 334.412 - Albemarle Sound, Pamlico Sound, Harvey Point and adjacent waters, NC; restricted area.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Albemarle Sound, Pamlico Sound... REGULATIONS § 334.412 Albemarle Sound, Pamlico Sound, Harvey Point and adjacent waters, NC; restricted area. (a) The area. Beginning on the north shore of Albemarle Sound and the easternmost tip of Harvey Point...

The Revolving Cage: The Views, Values, and Visions of James Harvey Robinson.

ERIC Educational Resources Information Center

Binford, Paul E.

This paper profiles James Harvey Robinson, an important scholar of history and social issues. The paper presents a biographical sketch of Harvey's early life and education and discusses his teaching and scholarly work, including his co-founding (with Charles A. Beard) of the New School for Social Research (New York) in 1919, noting that Robinson…

33 CFR 334.412 - Albemarle Sound, Pamlico Sound, Harvey Point and adjacent waters, NC; restricted area.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Albemarle Sound, Pamlico Sound... REGULATIONS § 334.412 Albemarle Sound, Pamlico Sound, Harvey Point and adjacent waters, NC; restricted area. (a) The area. Beginning on the north shore of Albemarle Sound and the easternmost tip of Harvey Point...

33 CFR 117.458 - Inner Harbor Navigation Canal, New Orleans.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Harbor Navigation Canal, New Orleans. (a) The draws of the SR 46 (St. Claude Avenue) bridge, mile 0.5 (GIWW mile 6.2 East of Harvey Lock), the SR 39 (Judge Seeber/Claiborne Avenue) bridge, mile 0.9 (GIWW mile 6.7 East of Harvey Lock), and the Florida Avenue bridge, mile 1.7 (GIWW mile 7.5 East of Harvey...

33 CFR 117.458 - Inner Harbor Navigation Canal, New Orleans.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Harbor Navigation Canal, New Orleans. (a) The draws of the SR 46 (St. Claude Avenue) bridge, mile 0.5 (GIWW mile 6.2 East of Harvey Lock), the SR 39 (Judge Seeber/Claiborne Avenue) bridge, mile 0.9 (GIWW mile 6.7 East of Harvey Lock), and the Florida Avenue bridge, mile 1.7 (GIWW mile 7.5 East of Harvey...

33 CFR 117.458 - Inner Harbor Navigation Canal, New Orleans.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Harbor Navigation Canal, New Orleans. (a) The draws of the SR 46 (St. Claude Avenue) bridge, mile 0.5 (GIWW mile 6.2 East of Harvey Lock), the SR 39 (Judge Seeber/Claiborne Avenue) bridge, mile 0.9 (GIWW mile 6.7 East of Harvey Lock), and the Florida Avenue bridge, mile 1.7 (GIWW mile 7.5 East of Harvey...

Biosynthesis of gold and silver chloride nanoparticles mediated by Crataegus pinnatifida fruit extract: in vitro study of anti-inflammatory activities.

PubMed

Kang, Jong Pyo; Kim, Yeon Ju; Singh, Priyanka; Huo, Yue; Soshnikova, Veronika; Markus, Josua; Ahn, Sungeun; Chokkalingam, Mohan; Lee, Hyun A; Yang, Deok Chun

2017-09-18

This research article investigates the one-pot synthesis of gold and silver chloride nanoparticles functionalized by fruit extract of Crataegus pinnatifida as reducing and stabilizing agents and their possible roles as novel anti-inflammatory agents. Hawthorn (C. pinnatifida) fruits are increasingly popular as raw materials for functional foods and anti-inflammatory potential agents because of abundant flavonoids. The reduction of auric chloride and silver nitrate by the aqueous fruit extract led to the formation of gold and silver chloride nanoparticles. The nanoparticles were further characterized by field emission transmission electron microscopy indicated that CP-AuNps and CP-AgClNps were hexagonal and cubic shape, respectively. According to X-ray diffraction results, the average crystallite sizes of CP-AuNps and CP-AgClNps were 14.20 nm and 24.80 nm. The biosynthesized CP-AgClNps served as efficient antimicrobial agents against Escherichia coli and Staphylococcus aureus. Furthermore, CP-AuNps and CP-AgClNps enhanced the DPPH radical scavenging activity of the fruit extract. Lastly, MTT assay of nanoparticles demonstrated low toxicity in murine macrophage (RAW264.7). Biosynthesized nanoparticles also reduced the production of the inflammatory cytokines including nitric oxide and prostaglandin E2 in lipopolysaccharide-induced RAW264.7 cells. Altogether, these findings suggest that CP-AuNps and CP-AgClNps can be used as novel drug carriers or biosensors with intrinsic anti-inflammatory activity.

[William Harvey revisited ].

PubMed

Steinke, Hubert

2015-07-01

William Harvey's discovery of the circulation of the blood is often described as a product of the Scientific Revolution of the Seventeenth Century. Modern research has, however, shown thatHarvey followed the Aristotelian research tradition and thus tried to reveal the purpose of the organs through examination of various animals. His publication of 1628 has to be read as an argument of natural philosophy, or, more precisely, as a series of linked observations, experiments and philosophical reasonings from which the existence of circulation has to be deduced as a logical consequence. Harvey did not consider experiments as superior to philosophical reasoning nor intended he to create a new system of medicine. He believed in the vitality of the heart and the blood and rejected Francis Bacon's empirism and the mechanistic rationalism of Descartes. Harvey's contribution and originality lied less in his single observations and experiments but in the manner how he linked them with critical reasoning and how he accepted, presented and defended the ensuing radical findings.

75 FR 71543 - Safety Zone; Gulf Intracoastal Waterway, Mile Marker 49.0 to 50.0, west of Harvey Locks, Bank to...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-24

...-AA00 Safety Zone; Gulf Intracoastal Waterway, Mile Marker 49.0 to 50.0, west of Harvey Locks, Bank to Bank, Bayou Blue Pontoon Bridge, Lafourche Parish, LA AGENCY: Coast Guard, DHS. ACTION: Temporary Final... Waterway extending from Mile Marker 49.0 to Mile Marker 50.0, bank to bank, West of Harvey Locks, Lafourche...

Hurricane Harvey Rainfall, Did It Exceed PMP and What are the Implications?

NASA Astrophysics Data System (ADS)

Kappel, B.; Hultstrand, D.; Muhlestein, G.

2017-12-01

Rainfall resulting from Hurricane Harvey reached historic levels over the coastal regions of Texas and Louisiana during the last week of August 2017. Although extreme rainfall from this landfalling tropical system is not uncommon in the region, Harvey was unique in that it persisted over the same general location for several days, producing volumes of rainfall not previously observed in the United States. Devastating flooding and severe stress to infrastructure in the region was the result. Coincidentally, Applied Weather Associates had recently completed an updated statewide Probable Maximum Precipitation (PMP) study for Texas. This storm proved to be a real-time test of the adequacy of those values. AWA calculates PMP following a storm-based approach. This same approach was use in the HMRs. Therefore inclusion of all PMP-type storms is critically important to ensuring that appropriate PMP values are produced. This presentation will discuss the analysis of the Harvey rainfall using the Storm Precipitation Analysis System (SPAS) program used to analyze all storms used in PMP development, compare the results of the Harvey rainfall analysis against previous similar storms, and provide comparisons of the Harvey rainfall against previous and current PMP depths. Discussion will be included regarding the implications of the storm on previous and future PMP estimates, dam safety design, and infrastructure vulnerable to extreme flooding.

A dark business, full of shadows: analogy and theology in William Harvey.

PubMed

Goldberg, Benjamin

2013-09-01

In a short work called De conceptione appended to the end of his Exercitationes de generatione animalium (1651), William Harvey developed a rather strange analogy. To explain how such marvelous productions as living beings were generated from the rather inauspicious ingredients of animal reproduction, Harvey argued that conception in the womb was like conception in the brain. It was mostly rejected at the time; it now seems a ludicrous theory based upon homonymy. However, this analogy offers insight into the structure and function of analogies in early modern natural philosophy. In this essay I hope to not only describe the complex nature of Harvey's analogy, but also offer a novel interpretation of his use of analogical reasoning, substantially revising the account offered by Guido Giglioni (1993). I discuss two points of conceptual change and negotiation in connection with Harvey's analogy, understanding it as both a confrontation between the border of the natural and the supernatural, as well as a moment in the history of psychology. My interpretation touches upon a number of important aspects, including why the analogy was rejected, how Harvey systematically deployed analogies according to his notions of natural philosophical method, how the analogy fits into contemporary discussions of analogies in science, and finally, how the analogy must be seen in the context of changing Renaissance notions of the science of the soul, ultimately confronting the problem of how to understand final causality in Aristotelian science. In connection with the last, I conclude the essay by turning to how Harvey embeds the analogy within a natural theological cosmology. Copyright © 2013. Published by Elsevier Ltd.

Performance of Oil Infrastructure during Hurricane Harvey

NASA Astrophysics Data System (ADS)

Bernier, C.; Kameshwar, S.; Padgett, J.

2017-12-01

Three major refining centers - Corpus Christi, Houston, and Beaumont/Port Arthur - were affected during Hurricane Harvey. Damage to oil infrastructure, especially aboveground storage tanks (ASTs), caused the release of more than a million gallons of hazardous chemicals in the environment. The objective of this presentation is to identify and gain a better understanding of the different damage mechanisms that occurred during Harvey in order to avoid similar failures during future hurricane events. First, a qualitative description of the damage suffered by ASTs during Hurricane Harvey is presented. Analysis of aerial imagery and incident reports indicate that almost all spills were caused by rainfall and the associated flooding. The largest spill was caused by two large ASTs that floated due to flooding in the Houston Ship Channel releasing 500,000 gallons of gasoline. The vulnerability of ASTs subjected to flooding was already well known and documented from previous storm events. In addition to flooding, Harvey also exposed the vulnerability of ASTs with external floating roof to extreme rainfall; more than 15 floating roofs sank or tilted due to rain water accumulation on them, releasing pollutants in the atmosphere. Secondly, recent fragility models developed by the authors are presented which allow structural vulnerability assessment of floating roofs during rainfall events and ASTs during flood events. The fragility models are then coupled with Harvey rainfall and flood empirical data to identify the conditions (i.e.: internal liquid height or density, drainage system design and efficiency, etc.) that could have led to the observed failures during Hurricane Harvey. Finally, the conditions causing tank failures are studied to propose mitigation measures to prevent future AST failures during severe storm, flood, or rainfall events.

Space Station Camera Captures New Views of Hurricane Harvey

NASA Image and Video Library

2017-08-24

The National Hurricane Center (NHC) upgraded the remnants of tropical storm Harvey to a tropical depression on August 23, 2017 at 11 a.m. EDT (1500 UTC). Harvey became better organized and was revived after moving from Mexico's Yucatan Peninsula into the Bay of Campeche. The warm waters of the Gulf of Mexico and favorable vertical wind shear promoted the regeneration of the tropical cyclone. This video includes views from The International Space Station recorded on August 24, 2017 at 6:15 p.m. Eastern Time.

The weight of a storm: what observations of Earth surface deformation can tell us about Hurricane Harvey

NASA Astrophysics Data System (ADS)

Borsa, A. A.; Mencin, D.; van Dam, T. M.

2017-12-01

Hurricane Harvey was the first major hurricane to impact the USA in over a decade, making landfall southwest of Houston, TX on August 26, 2017. Although Harvey was downgraded to a tropical storm shortly after landfall, it dropped a record amount of rain and was responsible for epic flooding across much of southeast Texas. While precipitation from a large storm like Harvey can be estimated from in-situ rain gages and Doppler radar, the accompanying surface water changes that lead to flooding are imperfectly observed due to the limited coverage of existing stream and lake level gages and because floodwaters inundate areas that are typically unmonitored. Earth's response to changes in surface loading provides an opportunity to observe the local hydrological response to Hurricane Harvey, specifically the dramatic changes in water storage coincident with and following the storm. Continuous GPS stations in southeastern Texas observed an average drop in land surface elevations of 1.8 cm following Harvey's landfall, followed by a gradual recovery to pre-storm levels over the following month. We interpret this surface motion as Earth's elastic response to the weight of cumulative rainfall during the storm, followed by rebound as that weight was removed by runoff and evapotranspiration (ET). Using observations of surface displacements from GPS stations in the HoustonNET and Plate Boundary Observatory networks, we model the daily water storage changes across Texas and Louisiana associated with Harvey. Because Harvey's barometric pressure low caused surface uplift at the cm level which temporarily obscured the subsidence signal due to precipitation, we model and remove the effect of atmospheric loading from the GPS data prior to our analysis. We also consider the effect on GPS position time series of non-tidal ocean loading due to the hurricane storm surge, which at the coast was an order of magnitude larger than loads due to precipitation alone. Finally, we use our results to estimate 1) the total precipitation load from the storm, 2) the spatial distribution of flooding, and 3) the runoff/ET component of water storage changes (incorporating independent estimates of precipitation).

NASA SMAP Images Show Texas Soil Moisture Conditions Before/After Hurricane Harvey's Landfall

NASA Image and Video Library

2017-08-29

Images of soil moisture conditions in Texas near Houston, generated by NASA's Soil Moisture Active Passive (SMAP) satellite before and after the landfall of Hurricane Harvey can be used to monitor changing ground conditions due to Harvey's rainfall. As seen in the left panel, SMAP observations show that soil surface conditions were already very wet a few days before the hurricane made landfall (August 21/22), with moisture levels in the 20 to 40 percent range. Such saturated soil surfaces contributed to the inability of water to infiltrate more deeply into soils, thereby increasing the likelihood of flooding. After Harvey made landfall, the southwest portion of Houston became exceptionally wet, as seen in the right panel image from August 25/26, signaling the arrival of heavy rains and widespread flooding. https://photojournal.jpl.nasa.gov/catalog/PIA21926

Harvey Cushing and the battle of Boston common: military medical preparedness for world war one.

PubMed

Rutkow, Eric; Rutkow, Ira

2010-07-01

To explore the events and people that shaped Harvey Cushing, one of the nation's leading surgeons, into a political actor as he rallied support for the issue of military medical preparedness for World War One. In a little remembered episode of American medical history, for 2 years before the nation's formal entry into World War One in April 1917, Harvey Cushing attempted to garner political and professional support for the idea of military medical preparedness. His efforts, including the proposed construction of a functioning Base Hospital on Boston Common, sparked controversy in a public that was torn between maintaining neutrality and going to war. An analysis of Harvey Cushing's unpublished letters, manuscripts, and papers located at the Yale University School of Medicine, New Haven, CT. While Harvey Cushing's crusade for military medical preparedness failed to win over the local public, it helped convince national military leaders that the civilian medical community was ready to assist in the war. This, in turn, laid the foundation for much of the American medical establishment's success on the battlefields of World War One. The disagreement surrounding the Battle of Boston Common, as Harvey Cushing had labeled the debate, reveals both how, even at the brink of war, ideas formulated on the war front could not be translated to the home front, and how early military medical preparedness, although national in character, was commanded by only a few select voices.

Coastal Erosion at Padre Island: Insights from UAV Surveys After Hurricane Harvey

NASA Astrophysics Data System (ADS)

Evans, A.; Wernette, P. A.; Houser, C.

2017-12-01

Hurricane Harvey caused widespread damage to coastal resources and communities when it made landfall north of Corpus Christi, Texas. Located immediately south of Corpus Christi, Padre Island National Seashore (PAIS) sustained significant beach and dune erosion due to strong wind and waves during Hurricane Harvey. This paper presents a post-storm assessment of the geomorphic changes caused Hurricane Harvey at PAIS. Post-storm geomorphology data was collected within 3 days of PAIS re-opening after the storm and again in late October 2017. Data consisted of oblique photographs, shore-normal survey-grade GNSS surveys, and high resolution (1.5 cm) UAV surveys encompassing a 14-km stretch of the beach and dunes. Comparison of post-storm surveys to 2009, 2010, 2011, and 2012 LiDAR series reveals that the beach and dune system sustained substantial erosion during Hurricane Harvey and that erosion is not evenly distributed along the coast. This paper provides valuable insight into how driving on the beach affects patterns of erosion during a storm. Rapid post-storm assessments, such as this paper, also represent valuable baselines for the National Park Service to assess environmental recovery.

The Peel Inlet-Harvey Estuary Study.

ERIC Educational Resources Information Center

Walker, Warren; Black, Ronald

1979-01-01

Describes how the department of physics of the Western Australian Institute of Technology (WAIT) has been involved in the Peel Inlet-Harvey Estuary study. An appendix which presents the departmental approach to curriculum matters is also included. (HM)

NPDES Permit for Glendale Colony and Harvey Farms in Montana

EPA Pesticide Factsheets

Under NPDES permit MT-0031819, Glendale Colony, Inc., and Harvey Farms, Inc. are authorized to discharge and must operate their facilities in accordance with provisions set forth herein.Indian Country on the Blackfeet Reserva

Use of C-band Sentinel-1 and L-band UAVSAR data for flood extent mapping during Hurricane Harvey

NASA Astrophysics Data System (ADS)

Lakshmi, V.; Kundu, S.; Torres, R.

2017-12-01

Hurricane Harvey was one of the most destructive storms that struck the Houston area in August 2017 causing loss of life and property. In this study, an estimation of flooding extent is done using two sets of microwave remote sensing data, Unmanned Aerial Vehicle Synthetic Aperture Radar (UAVSAR) and Sentinel-1. UAVSAR is an L-band SAR (Synthetic Aperture Radar) data which is an airborne repeat-pass interferometric observation system and has 16 km swath. Sentinel-1 is the C band microwave data developed by European Space Agency covering a large area (250 km). Data are analyzed to examine the flood extent over Houston during Harvey. Flood extent mapping is carried out using the Sentinel-1 data and UAVSAR using backscatter signatures which displays the extent of changes and destruction during the flood. Keywords: Harvey, UAVSAR, Sentinel-1, flood extent

Extreme Rainfall from Hurricane Harvey (2017): Intercomparisons of WRF Simulations and Polarimetric Radar Fields

NASA Astrophysics Data System (ADS)

Yang, L.; Smith, J. A.; Liu, M.; Baeck, M. L.; Chaney, M. M.; Su, Y.

2017-12-01

Hurricane Harvey made landfall on 25 August 2017 and produced more than a meter of rain during a four-day period over eastern Texas, making it the wettest tropical cyclone on record in the United States. Extreme rainfall from Harvey was predominantly related to the dynamics and structure of outer rain bands. In this study, we provide details of the extreme rainfall produced by Hurricane Harvey. The principal research questions that motivate this study are: (1) what are the key microphysical properties of extreme rainfall from landfalling tropical cyclones and (2) what are the capabilities and deficiencies of existing bulk microphysics parameterizations from the physical models in capturing them. Our analyses are centered on intercomparisons of high-resolution simulations using the Weather Research and Forecasting (WRF) model and polarimetric radar fields from KHGX (Houston, Texas) WSR-88D. The WRF simulations accurately capture the track and intensity of Hurricane Harvey. Multi-rainband structure and its key evolution features are also well represented in the simulations. Two microphysics parameterizations (WSM6 and WDM6) are tested in this study. Radar reflectivity and differential reflectivity fields simulated by the WRF model are compared with polarimetric radar observations. An important feature for the extreme rainfall from Hurricane Harvey is the sharp boundary of spatial rainfall accumulation along the coast (with torrential rainfall distributed over Houston and its surrounding inland areas). We will examine the role of land-sea contrasts in dictating storm structure and evolution from both WRF simulations and polarimetric radar fields. Implications for improving hurricane rainfall forecasts and estimates will be provided.

Estimating the human influence on Hurricanes Harvey, Irma and Maria

NASA Astrophysics Data System (ADS)

Wehner, M. F.; Patricola, C. M.; Risser, M. D.

2017-12-01

Attribution of the human-induced climate change influence on the physical characteristics of individual extreme weather events has become an advanced science over the past decade. However, it is only recently that such quantification of anthropogenic influences on event magnitudes and probability of occurrence could be applied to very extreme storms such as hurricanes. We present results from two different classes of attribution studies for the impactful Atlantic hurricanes of 2017. The first is an analysis of the record rainfall amounts during Hurricane Harvey in the Houston, Texas area. We analyzed observed precipitation from the Global Historical Climatology Network with a covariate-based extreme value statistical analysis, accounting for both the external influence of global warming and the internal influence of ENSO. We found that human-induced climate change likely increased Hurricane Harvey's total rainfall by at least 19%, and likely increased the chances of the observed rainfall by a factor of at least 3.5. This suggests that changes exceeded Clausius-Clapeyron scaling, motivating attribution studies using dynamical climate models. The second analysis consists of two sets of hindcast simulations of Hurricanes Harvey, Irma, and Maria using the Weather Research and Forecasting model (WRF) at 4.5 km resolution. The first uses realistic boundary and initial conditions and present-day greenhouse gas forcings while the second uses perturbed conditions and pre-industrial greenhouse has forcings to simulate counterfactual storms without anthropogenic influences. These simulations quantify the fraction of Harvey's precipitation attributable to human activities and test the super Clausius-Clapeyron scaling suggested by the observational analysis. We will further quantify the human influence on intensity for Harvey, Irma, and Maria.

Monitoring and Mapping the Hurricane Harvey Flooding in Houston, Texas.

NASA Astrophysics Data System (ADS)

Balaji Bhaskar, M. S.

2017-12-01

Monitoring and Mapping the Hurricane Harvey Flooding in Houston, Texas.Urban flooding is a hazard that causes major destruction and loss of life. High intense precipitation events have increased significantly in Houston, Texas in recent years resulting in frequent river and bayou flooding. Many of the historical storm events such as Allison, Rita and Ike have caused several billion dollars in losses for the Houston-Galveston Region. A category 4 Hurricane Harvey made landfall on South Texas resulting in heavy precipitation from Aug 25 to 29 of 2017. About 1 trillion gallons of water fell across Harris County over a 4-day period. This amount of water covers Harris County's 1,800 square miles with an average of 33 inches of water. The long rain event resulted in an average 40inch rainfall across the area in several rain gauges and the maximum rainfall of 49.6 inches was recorded near Clear Creek. The objectives of our study are to 1) Process the Geographic Information System (GIS) and satellite data from the pre and post Hurricane Harvey event in Houston, Texas and 2) Analyze the satellite imagery to map the nature and pattern of the flooding in Houston-Galveston Region. The GIS data of the study area was downloaded and processed from the various publicly available resources such as Houston Galveston Area Council (HGAC), Texas Commission of Environmental Quality (TCEQ) and Texas Natural Resource Information Systems (TNRIS). The satellite data collected soon after the Harvey flooding event were downloaded and processed using the ERDAS image processing software. The flood plain areas surrounding the Brazos River, Buffalo Bayou and the Addicks Barker reservoirs showed severe inundation. The different watershed areas affected by the catastrophic flooding in the wake of Hurricane Harvey were mapped and compared with the pre flooding event.

An observational and modeling study of the August 2017 Florida climate extreme event.

NASA Astrophysics Data System (ADS)

Konduru, R.; Singh, V.; Routray, A.

2017-12-01

A special report on the climate extremes by the Intergovernmental Panel on Climate Change (IPCC) elucidates that the sole cause of disasters is due to the exposure and vulnerability of the human and natural system to the climate extremes. The cause of such a climate extreme could be anthropogenic or non-anthropogenic. Therefore, it is challenging to discern the critical factor of influence for a particular climate extreme. Such kind of perceptive study with reasonable confidence on climate extreme events is possible only if there exist any past case studies. A similar rarest climate extreme problem encountered in the case of Houston floods and extreme rainfall over Florida in August 2017. A continuum of hurricanes like Harvey and Irma targeted the Florida region and caused catastrophe. Due to the rarity of August 2017 Florida climate extreme event, it requires the in-depth study on this case. To understand the multi-faceted nature of the event, a study on the development of the Harvey hurricane and its progression and dynamics is significant. Current article focus on the observational and modeling study on the Harvey hurricane. A global model named as NCUM (The global UK Met office Unified Model (UM) operational at National Center for Medium Range Weather Forecasting, India, was utilized to simulate the Harvey hurricane. The simulated rainfall and wind fields were compared with the observational datasets like Tropical Rainfall Measuring Mission rainfall datasets and Era-Interim wind fields. The National Centre for Environmental Prediction (NCEP) automated tracking system was utilized to track the Harvey hurricane, and the tracks were analyzed statistically for different forecasts concerning the Harvey hurricane track of Joint Typhon Warning Centre. Further, the current study will be continued to investigate the atmospheric processes involved in the August 2017 Florida climate extreme event.

Effects of an aqueous extract of Crataegus pinnatifida Bge. var. major N.E.Br. fruit on experimental atherosclerosis in rats.

PubMed

Zhang, Jianyong; Liang, Rixin; Wang, Lan; Yan, Renyi; Hou, Rui; Gao, Shuangrong; Yang, Bin

2013-07-09

Atherosclerosis (AS) can result in severe cardiovascular diseases. Early indications of AS include disorders in lipid metabolism, inflammatory responses, and endothelial dysfunction. Statins are the preferred drugs for stabilizing atherosclerotic plaques because of their lipid-lowering, anti-inflammation and endothelial-protection activities. However, they can exhibit side effects and are effective in only one-third of patients. Many natural products (especially traditional Chinese medicines (TCMs)) possessing similar lipid-lowering, anti-inflammation and antioxidant activities are of interest in many studies exploring new AS drug therapy. The widely distributed hawthorn is used to prevent and cure heart disease not only in China but also in the United States and several European countries. For example, the fruit of Crataegus pinnatifida Bge. and Crataegus pinnatifida Bge. var. major N.E.Br. (a commonly used hawthorn fruit in China) is used in combination with other TCMs to treat AS. Studies have also shown that the water extracts of these two hawthorn fruits are effective against hyperlipidemia by lowering lipid levels, reducing endothelial dysfunction, and inhibiting inflammation. The aim of the study is to investigate the effect and possible mechanisms of the aqueous extract of Crataegus pinnatifida var. major on AS rats. The fruit of Crataegus pinnatifida var. major was extracted with 70% ethanol; the ethanol extract was chromatographed on a D101 macroporous resin to obtain a sugar-free aqueous extract (AECP). Atherosclerotic rats were fed a high-fat diet and injected with vitamin D3 and ovalbumin. Rats were divided into five groups: normal, model, model plus simvastatin, model plus low-dose AECP, and model plus high-dose AECP. AECP and simvastatin were administered (via the intragastric route) to AECP groups and the simvastatin group. For normal and model groups, water was given for 4 weeks. After 12 weeks, levels of total cholesterol (TC), triglyceride (TG), low-density lipoprotein-cholesterol (LDL-C) and high-density lipoprotein-cholesterol (HDL-C) in blood were measured by an automatic biochemistry analyzer. Serum concentrations of interleukin (IL)-1β, IL-8, nitric oxide (NO), endothelin (ET), 6-keto-prostaglandin F1α (6-keto-PGF1α) and thromboxane B2 (TXB2) were determined by radioimmunoassay (RIA). Serum concentrations of C-reactive protein (CRP) and IL-18 were measured by enzyme-linked immunosorbent assay (ELISA). Pathological changes in arteries were observed using an optical microscope and the intima-media thickness (IMT) calculated. Cholesterol deposition was evaluated by filipin staining. Chemical ingredients in AECP were analyzed by qualitative and quantitative means by high-performance liquid chromatography (HPLC). AECP significantly reduced the levels of TC, TG and LDL-C but increased HDL-C levels. It also decreased the concentrations of CRP, IL-1β, IL-8 and IL-18. AECP increased levels of ET and TXB2 but increased 6-keto-PGF1α levels. Histopathological examination showed that AECP inhibited pathological changes in the arteries of AS rats and reduced IMT. Chemical analysis suggested that the main components of AECP were chlorogenic acid, procyanidin B2, (-)-epicatechin, rutin and isoquercitrin. These data suggest that AECP can inhibit AS progression in high-fat-diet-fed rats. Possible mechanisms of action include improvement of lipid metabolism, decrease in inflammatory cytokine responses, and protection of the endothelium. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Laser Focus

ERIC Educational Resources Information Center

Stuart, Reginald

2011-01-01

Hampton University President William Harvey's initial readings of proton therapy for cancer sparked his interest. Within a few months, Dr. Harvey was assigning widely respected Hampton nuclear physicist Dr. Cynthia Keppel to do more exploration. Today, the new $225 million Hampton University Proton Therapy Institute, one of eight therapy sites in…

Correction to: Extreme Precipitation, Public Health Emergencies, and Safe Drinking Water in the USA.

PubMed

Exum, Natalie G; Betanzo, Elin; Schwab, Kellogg J; Chen, Thomas Y J; Guikema, Seth; Harvey, David E

2018-06-01

Unfortunately, the original publication of this article contained mistakes. The publisher introduced an error after proofreading where the name of the co-author was mistakenly captured as "David P. E. Harvey". The correct name should be "David E. Harvey".

Effects of Dietary Fermented Seaweed and Seaweed Fusiforme on Growth Performance, Carcass Parameters and Immunoglobulin Concentration in Broiler Chicks

PubMed Central

Choi, Y. J.; Lee, S. R.; Oh, J-W.

2014-01-01

This study was conducted to investigate the effects of brown seaweed (Undaria pinnatifida) by-product and seaweed fusiforme (Hizikia fusiformis) by-product supplementation on growth performance and blood profiles including serum immunoglobulin (Ig) in broilers. Fermentation of seaweeds was conducted by Bacillus subtilis and Aspergillus oryzae. In a 5-wk feeding trial, 750 one-d-old broiler chicks were divided into 5 groups, and were assigned to the control diet or experimental diets including control+0.5% brown seaweed (BS) by-product, control+0.5% seaweed fusiforme (SF) by-product, control+0.5% fermented brown seaweed (FBS) by-product, and control+0.5% fermented seaweed fusiforme (FSF) by-product. As a consequence, body weight gain (BWG) and gain:feed of seaweed by-product groups were clearly higher, when compared to those of control diet group from d 18 to 35 and the entire experimental period (p<0.05). In mortality rate, seaweed by-product groups were significantly lower when compared to control diet group during entire experimental period (p<0.05). However, Feed Intake of experimental diets group was not different from that of the control group during the entire experimental period. Whereas, Feed Intake of fermented seaweed by-product groups was lower than that of non-fermented seaweed groups (p<0.05). Total organ weights, lipids, and glutamic oxalacetic transaminase (GOT) of all treatment groups were not different from those of control group. However, glutamic pyruvate transaminase (GPT) of all treatment groups was higher than that of control group at d 17 (p<0.05). In case of serum Igs concentration, the concentration of IgA antibody in BS, SF, FSF treatment groups was significantly higher than in control group at d 35 (p<0.01). IgA concentration in FBS supplementation groups was negligibly decreased when compared to the control group. IgM concentration in the serums of all treatment groups was significantly higher than in control group (p<0.05) and in fermented seaweed by-product groups were much higher than in non-fermented seaweed groups (p<0.05). On the other hand, IgG concentrations in all treatment groups were lower than in control group (p<0.05). Taken together, our results suggest that by-product dietary supplementation of BS, SF, FBS, and FSF in poultry may provide positive effects of growth performance and immune response. PMID:25050025

The Dilemma of Campus Upkeep: An Interview with Harvey Kaiser.

ERIC Educational Resources Information Center

Christian, Roslyn Stewart

1984-01-01

Deferred maintenance is reaching crisis proportion on many campuses. An overview of this priority for governing boards and a look at how trustees should be involved is presented in an interview of Harvey Kaiser, vice president for facilities administration at Syracuse University. (Author/MLW)

Guidelines for Software Engineering Education Version 1.0

DTIC Science & Technology

1999-11-01

Turbo Pascal and Software Design. Sudbury, Massachusetts: Jones and Bartlett, 1997. " Deitel, Harvey M. & Deitel, Paul J. C++: How to Program . Upper...Saddle River, New Jersey: Prentice-Hall, 1997. " Deitel, Harvey M. & Deitel, Paul J. Java: How to Program . Upper Saddle River, New Jersey: Prentice-Hall

4. Photocopy of measured drawing (from Robert R. Harvey's 'Historic ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Photocopy of measured drawing (from Robert R. Harvey's 'Historic Stone Architecture of Winterset, Iowa, Prior To and During the Civil War Period,' Unpublished Report, Iowa State University, (Ames, IA), 1960.) FLOOR PLAN, 1944 ('Fig. 4-D') - M. R. Tidrick House, 122 South Fourth Avenue, Winterset, Madison County, IA

3. Photocopy of measured drawing (from Robert R. Harvey's 'Historic ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Photocopy of measured drawing (from Robert R. Harvey's 'Historic Stone Architecture of Winterset, Iowa, Prior To and During the Civil War Period,' Unpublished Report, Iowa State University, (Ames, IA), 1960.) FLOOR PLAN, 1874 ('Fig. 4-C') - M. R. Tidrick House, 122 South Fourth Avenue, Winterset, Madison County, IA

2. Photocopy of measured drawing (from Robert R. Harvey's 'Historic ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Photocopy of measured drawing (from Robert R. Harvey's 'Historic Stone Architecture of Winterset, Iowa, Prior To and During the Civil War Period,' Unpublished Report, Iowa State University, (Ames, IA), 1960.) FLOOR PLAN, 1866 ('Fig 4-B') - M. R. Tidrick House, 122 South Fourth Avenue, Winterset, Madison County, IA

77 FR 32393 - Drawbridge Operation Regulation; Gulf Intracoastal Waterway, LA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-01

... across the Harvey Canal Route, Gulf Intracoastal Waterway (GIWW), mile 2.8 at New Orleans, Jefferson... Boulevard Bridge across the Harvey Canal Route, Intracoastal Waterway, mile 2.8 at New Orleans, Jefferson... Transportation, West Building Ground Floor, Room W12-140, 1200 New Jersey Avenue SE., Washington, DC 20590...

75 FR 39632 - Regulated Navigation Area; Gulf Intracoastal Waterway, Inner Harbor Navigation Canal, Harvey...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-12

..., Algiers Canal, New Orleans, LA; Correction ACTION: Interim rule; Correction. SUMMARY: In the Federal... Area; Gulf Intracoastal Waterway, Inner Harbor Navigation Canal, Harvey Canal, Algiers Canal, New Orleans, LA into the Code of Federal Regulations. That publication contained an error in the DATES section...

Harvey Mudd College: Technology Integration Offers Unique Opportunities for Undergraduates.

ERIC Educational Resources Information Center

Barna, John; Winstead, Jim

1993-01-01

Describes undergraduate projects at Harvey Mudd College (California) that use advanced laboratory equipment and procedures normally reserved for graduate students. Examples are given in experimental biology (e.g., digital imaging and DNA analysis), in physics (e.g., using satellites to study earthquake faults), and in mathematics (e.g., teaching…

1. Photocopy of measured drawing (from Robert R. Harvey's 'Historic ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Photocopy of measured drawing (from Robert R. Harvey's 'Historic Stone Architecture of Winterset, Iowa, Prior To and During the Civil War Period,' Unpublished Report, Iowa State University, (Ames, IA), 1960.) FLOOR PLAN, 1856 ('Fig. 4-A') - M. R. Tidrick House, 122 South Fourth Avenue, Winterset, Madison County, IA

Making Hollow Men

ERIC Educational Resources Information Center

Harvey, Charles W.

2010-01-01

In this essay Charles Harvey offers a worried reflection on the range, extent, depth, affects, and effects of the perpetual assessment of the person in (post)industrial nations in the contemporary world. Harvey begins his analysis by appealing to the work of Martin Heidegger, Michel Foucault, and Jean Baudrillard to provide an interpretive…

Protective effect of extract of Crataegus pinnatifida pollen on DNA damage response to oxidative stress.

PubMed

Cheng, Ni; Wang, Yuan; Gao, Hui; Yuan, Jialing; Feng, Fan; Cao, Wei; Zheng, Jianbin

2013-09-01

The protective effect of extract of Crataegus pinnatifida (Rosaceae) pollen (ECPP) on the DNA damage response to oxidative stress was investigated and assessed with an alkaline single-cell gel electrophoresis (SCGE) assay and pBR322 plasmid DNA breaks in site-specific and non-site-specific systems. Total phenolic content, total flavonoid content, individual phenolic compounds, antioxidant activities (1,1-diphenyl-2-picrylhydrazyl (DPPH), radical scavenging activity, FRAP, and chelating activity) were also determined. The results showed that ECPP possessed a strong ability to protect DNA from being damaged by hydroxyl radicals in both the site-specific system and the non-site-specific system. It also exhibited a cytoprotection effect in mouse lymphocytes against H₂O₂-induced DNA damage. These protective effects may be related to its high total phenolic content (17.65±0.97 mg GAE/g), total flavonoid content (8.04±0.97 mg rutin/g), strong free radical scavenging activity and considerable ferrous ion chelating ability (14.48±0.21 mg Na₂EDTA/g). Copyright © 2013 Elsevier Ltd. All rights reserved.

Phytochemical Characteristics, Free Radical Scavenging Activities, and Neuroprotection of Five Medicinal Plant Extracts

PubMed Central

Chang, Chia Lin; Lin, Che San; Lai, Guia Hung

2012-01-01

The objective of this study was to determine phytochemical characteristics, chemiluminescence antioxidant capacities, and neuroprotective effects on PC12 cells for methanol extracts of Spatholobus suberectus, Uncaria rhynchophylla, Alpinia officinarum, Drynaria fortunei, and Crataegus pinnatifida. The C. pinnatifida extract (CPE) afforded the greatest yield and total phenolic content. The S. suberectus extract (SSE) yielded the greatest total flavonoid content. The U. rhynchophylla extract (URE) produced the greatest total tannin content, and the A. officinarum extract (AOE) produced the greatest total triterpenoid content. The D. fortunei extract, assayed using horseradish peroxidase-luminol-hydrogen peroxide (H2O2), and AOE using pyrogallol-luminol assay each exhibited better antioxidant activity than the L-ascorbic acid and 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid did. The CPE, SSE, and URE presented neurogrowth effects and neuroprotective activities on H2O2-induced PC12 cell death at 0.5–5.0 μg/mL. The CPE represents a promising medicinal plant source for the treatment of H2O2-induced neurodegenerative disease, because of its useful phytochemical characteristics. PMID:21845204

An extract of Crataegus pinnatifida fruit attenuates airway inflammation by modulation of matrix metalloproteinase-9 in ovalbumin induced asthma.

PubMed

Shin, In Sik; Lee, Mee Young; Lim, Hye Sun; Ha, Hyekyung; Seo, Chang Seob; Kim, Jong-Choon; Shin, Hyeun Kyoo

2012-01-01

Crataegus pinnatifida (Chinese hawthorn) has long been used as a herbal medicine in Asia and Europe. It has been used for the treatment of various cardiovascular diseases such as myocardial weakness, tachycardia, hypertension and arteriosclerosis. In this study, we investigated the anti-inflammatory effects of Crataegus pinnatifida ethanolic extracts (CPEE) on Th2-type cytokines, eosinophil infiltration, expression of matrix metalloproteinase (MMP)-9, and other factors, using an ovalbumin (OVA)-induced murine asthma model. Airways of OVA-sensitized mice exposed to OVA challenge developed eosinophilia, mucus hypersecretion and increased cytokine levels. CPEE was applied 1 h prior to OVA challenge. Mice were administered CPEE orally at doses of 100 and 200 mg/kg once daily on days 18-23. Bronchoalveolar lavage fluid (BALF) was collected 48 h after the final OVA challenge. Levels of interleukin (IL)-4 and IL-5 in BALF were measured using enzyme-linked immunosorbent (ELISA) assays. Lung tissue sections 4 µm in thickness were stained with Mayer's hematoxylin and eosin for assessment of cell infiltration and mucus production with PAS staining, in conjunction with ELISA, and Western blot analyses for the expression of MMP-9, intercellular adhesion molecule (ICAM)-1 and vascular cell adhesion molecule (VCAM)-1 protein expression. CPEE significantly decreased the Th2 cytokines including IL-4 and IL-5 levels, reduced the number of inflammatory cells in BALF and airway hyperresponsiveness, suppressed the infiltration of eosinophil-rich inflammatory cells and mucus hypersecretion and reduced the expression of ICAM-1, VCAM-1 and MMP-9 and the activity of MMP-9 in lung tissue of OVA-challenged mice. These results showed that CPEE can protect against allergic airway inflammation and can act as an MMP-9 modulator to induce a reduction in ICAM-1 and VCAM-1 expression. In conclusion, we strongly suggest the feasibility of CPEE as a therapeutic drug for allergic asthma.

An Extract of Crataegus pinnatifida Fruit Attenuates Airway Inflammation by Modulation of Matrix Metalloproteinase-9 in Ovalbumin Induced Asthma

PubMed Central

Lim, Hye Sun; Ha, Hyekyung; Seo, Chang Seob; Kim, Jong-Choon; Shin, Hyeun Kyoo

2012-01-01

Background Crataegus pinnatifida (Chinese hawthorn) has long been used as a herbal medicine in Asia and Europe. It has been used for the treatment of various cardiovascular diseases such as myocardial weakness, tachycardia, hypertension and arteriosclerosis. In this study, we investigated the anti-inflammatory effects of Crataegus pinnatifida ethanolic extracts (CPEE) on Th2-type cytokines, eosinophil infiltration, expression of matrix metalloproteinase (MMP)-9, and other factors, using an ovalbumin (OVA)-induced murine asthma model. Methods/Principal Finding Airways of OVA-sensitized mice exposed to OVA challenge developed eosinophilia, mucus hypersecretion and increased cytokine levels. CPEE was applied 1 h prior to OVA challenge. Mice were administered CPEE orally at doses of 100 and 200 mg/kg once daily on days 18–23. Bronchoalveolar lavage fluid (BALF) was collected 48 h after the final OVA challenge. Levels of interleukin (IL)-4 and IL-5 in BALF were measured using enzyme-linked immunosorbent (ELISA) assays. Lung tissue sections 4 µm in thickness were stained with Mayer’s hematoxylin and eosin for assessment of cell infiltration and mucus production with PAS staining, in conjunction with ELISA, and Western blot analyses for the expression of MMP-9, intercellular adhesion molecule (ICAM)-1 and vascular cell adhesion molecule (VCAM)-1 protein expression. CPEE significantly decreased the Th2 cytokines including IL-4 and IL-5 levels, reduced the number of inflammatory cells in BALF and airway hyperresponsiveness, suppressed the infiltration of eosinophil-rich inflammatory cells and mucus hypersecretion and reduced the expression of ICAM-1, VCAM-1 and MMP-9 and the activity of MMP-9 in lung tissue of OVA-challenged mice. Conclusions These results showed that CPEE can protect against allergic airway inflammation and can act as an MMP-9 modulator to induce a reduction in ICAM-1 and VCAM-1 expression. In conclusion, we strongly suggest the feasibility of CPEE as a therapeutic drug for allergic asthma. PMID:23029210

1. Photocopy of measured drawing (from Robert R. Harvey's 'Historic ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Photocopy of measured drawing (from Robert R. Harvey's 'Historic Stone Architecture of Winterset, Iowa, Prior To and During the Civil War Period,' Unpublished Report, Iowa State University, (Ames, IA), 1960.) FLOOR PLAN, ORIGINAL HOUSE ('Fig. 5-A') - J. G. Vawter House, First Avenue & South Street, Winterset, Madison County, IA

4. Photocopy of measured drawing (from Robert R. Harvey's 'Historic ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Photocopy of measured drawing (from Robert R. Harvey's 'Historic Stone Architecture of Winterset, Iowa, Prior To and During the Civil War Period,' Unpublished Report, Iowa State University, (Ames, IA), 1960.) FLOOR PLAN, THIRD ADDITION ('Fig. 5-D') - J. G. Vawter House, First Avenue & South Street, Winterset, Madison County, IA

3. Photocopy of measured drawing (from Robert R. Harvey's 'Historic ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Photocopy of measured drawing (from Robert R. Harvey's 'Historic Stone Architecture of Winterset, Iowa, Prior To and During the Civil War Period,' Unpublished Report, Iowa State University, (Ames, IA), 1960.) FLOOR PLAN, SECOND ADDITION ('Fig. 5-C') - J. G. Vawter House, First Avenue & South Street, Winterset, Madison County, IA

2. Photocopy of measured drawing (from Robert R. Harvey's 'Historic ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Photocopy of measured drawing (from Robert R. Harvey's 'Historic Stone Architecture of Winterset, Iowa, Prior To and During the Civil War Period,' Unpublished Report, Iowa State University, (Ames, IA), 1960.) FLOOR PLAN, SHOWING FIRST ADDITION ('Fig. 5-B') - J. G. Vawter House, First Avenue & South Street, Winterset, Madison County, IA

Integration of Ground, Buoys, Satellite and Model data to map the Changes in Meteorological Parameters Associated with Harvey Hurricane

NASA Astrophysics Data System (ADS)

Chauhan, A.; Sarkar, S.; Singh, R. P.

2017-12-01

The coastal areas have dense onshore and marine observation network and are also routinely monitored by constellation of satellites. The monitoring of ocean, land and atmosphere through a range of meteorological parameters, provides information about the land and ocean surface. Satellite data also provide information at different pressure levels that help to access the development of tropical storms and formation of hurricanes at different categories. Integration of ground, buoys, satellite and model data showing the changes in meteorological parameters during the landfall stages of hurricane Harvey will be discussed. Hurricane Harvey was one of the deadliest hurricanes at the Gulf coast which caused intense flooding from the precipitation. The various observation networks helped city administrators to evacuate the coastal areas, that minimized the loss of lives compared to the Galveston hurricane of 1900 which took 10,000 lives. Comparison of meteorological parameters derived from buoys, ground stations and satellites associated with Harvey and 2005 Katrina hurricane present some of the interesting features of the two hurricanes.

77 FR 5308 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-02

............ GRIMM KATJA GROENEN FRANK GRONER ELIYAHU DAVID GRONING MARC E GUNNARSSON GUNNAR-THOR....... BJORNSSON... ARTHUR HANSSON KARL STEFAN HARPER-VANDAMME BRENDA CHRISTIAN HARVEY BRUCE E HARVEY RALPH DIETER HASLER... HILLIARD ELAINE GARDINER WELCH HO LESLIE SAI KIT HOCHHEIMER SUZANNE TRUDY HOLUB BARBARA RENE HRYNIUK LYNN E...

Publications and Presentations of the Ophthalmology Branch, U.S. Air Force School of Aerospace Medicine, 2006-2010

DTIC Science & Technology

2013-12-01

LASER ASSISTED IN SITU KERATOMILEUSIS ( LASIK ) EYES Aaron MT, Gooch JM, Harvey RR, Davis RE, and Tutt RC Abstract: Aviation, Space, and Environmental...AZ; 9-13 May 2010 10. EFFECT OF HIGH ALTITUDE ON LASER ASSISTED IN SITU KERATOMILEUSIS ( LASIK ) EYES Aaron MT, Gooch JM, Harvey RR, Davis RE, and

Quantitative attribution of climate effects on Hurricane Harvey’s extreme rainfall in Texas

NASA Astrophysics Data System (ADS)

Wang, S.-Y. Simon; Zhao, Lin; Yoon, Jin-Ho; Klotzbach, Phil; Gillies, Robert R.

2018-05-01

Hurricane Harvey made landfall in August 2017 as the first land-falling category 4 hurricane to hit the state of Texas since Hurricane Carla in September 1961. While its intensity at landfall was notable, most of the vast devastation in the Houston metropolitan area was due to Harvey stalling near the southeast Texas coast over the next several days. Harvey’s long-duration rainfall event was reminiscent of extreme flooding that occurred in the neighboring state of Louisiana: both of which were caused by a stalled tropical low-pressure system producing four days of intense precipitation. A quantitative attribution analysis of Harvey’s rainfall was conducted using a mesoscale atmospheric model forced by constrained boundary and initial conditions that had their long-term climate trends removed. The removal of the various trends of the boundary and initial conditions minimizes the effects of warming in the air and the ocean surface on Harvey. The 60 member ensemble simulations suggest that post-1980 climate warming could have contributed to the extreme precipitation that fell on southeast Texas during 26–29 August 2017 by approximately 20%, with an interquartile range of 13%–37%. While the attribution outcome could be model dependent, this downscaling approach affords the closest means possible of a case-to-case comparison for event attribution, complementing other statistics-based attribution studies on Harvey. Further analysis of a global climate model tracking Harvey-like stalling systems indicates an increase in storm frequency and intensity over southeast Texas through the mid-21st century.

77 FR 46287 - Safety Zone; Gulf Intracoastal Waterway, Mile Marker 35.2 to Mile Marker 35.5, West of Harvey...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-03

...-AAOO Safety Zone; Gulf Intracoastal Waterway, Mile Marker 35.2 to Mile Marker 35.5, West of Harvey.... SUMMARY: The Coast Guard is re-establishing a temporary safety zone in the Gulf Intracoastal Waterway.... This Safety Zone is needed to protect the general public, vessels and tows from destruction, loss or...

Theorising "Geo-Identity" and David Harvey's Space: School Choices of the Geographically Bound Middle-Class

ERIC Educational Resources Information Center

Rowe, Emma

2015-01-01

This paper draws on David Harvey's theories of absolute and relational space in order to critique geographically bound school choices of the gentrified middle-class in the City of Melbourne, Australia. The paper relies on interviews with inner-city school choosers as generated by a longitudinal ethnographic school choice study. I argue that the…

Germania Quo Vadis?: Dynamics of Change in German Security Policy

DTIC Science & Technology

2007-06-01

Keohane, Robert O., Michael Brecher and Frank Harveys, eds. Institutional Theory in international Relations. In: Millennial Reflections on International...Hegemony: Cooperation and Discord in the World Political Economy, (Princeton University Press, 1984), pp. 78-109; Robert O. Keohane, “ Institutional ... Theory in international Relations,” in Michael Brecher and Frank Harveys, eds., Millennial Reflections on International Studies (University of Michigan

The Wonderlic Personnel Test and Elementary Cognitive Tasks as Predictors of Religious Sectarianism, Scriptural Acceptance and Religious Questioning

ERIC Educational Resources Information Center

Bertsch, Sharon; Pesta, Bryan J.

2009-01-01

Lynn, Harvey and Nyborg [Lynn, R., Harvey, J., & Nyborg, H. (in press). Average intelligence predicts atheism rates across 137 nations. "Doi:10.1016/j.intell.2008.03.004".] discovered that average intelligence (IQ) co-varies with national atheism rates. Extending this work, we investigated relationships among individual IQ scores,…

Learning from Harvey Milk: The Limits and Opportunities of One Hero to Teach about LGBTQ People and Issues

ERIC Educational Resources Information Center

Donahue, David M.

2014-01-01

Highlighting a hero is a common response to including the history of marginalized people in the curriculum. Harvey Milk is becoming that hero as social studies curriculum responds to calls for including LGBTQ people. By studying Milk, what might young people learn about LGBTQ people, issues, and movements? What opportunities and limitations exist…

Rest-rotation grazing at Harvey Valley. . .range health, cattle gains, costs

Treesearch

Raymond D. Ratliff; Jack N. Reppert; Richard J. McConnen

1972-01-01

A trial of rest-rotation grazing was started in 1954 on the Harvey Valley allotment of the Lassen National Forest, northern California. This paper evaluates progress observed to 1966. Ecologically the program is considered sound. And after only a decade, the allotment was in better condition than allotments grazed season-long. Cattle weight gains were acceptable, and...

The history of the theory of the circulation of the blood.

PubMed

Rampling, M W

2016-01-01

An obvious candidate for the seminal event in the history of haemorheology is Harvey's presentation of the concept of the circulation of the blood. Prior to this, the ideas concerning the movement of blood were based, in Europe and Middle East, largely on the principles laid down by Galen, and these had been, in effect, dogma for nearly a millennium and a half. These principles were basically that blood is formed in the liver, thence it travels to the bodily organs and is consumed -hence there is one-way flow and no circulation of the blood at all. Harvey's revolutionary idea that blood circulates repeatedly around the cardiovascular system laid the foundation for haemorheology because once that idea was accepted then the fluidity of the blood immediately became potentially of crucial importance - and haemorheology was conceived. In this paper the ideas that preceded Harvey will be presented, i.e. those of Galen, Ibn al-Nafis, Vesalius, Fabricius and Colombo etc. Harvey's awareness of this background, due mainly to time spent in Padua, triggered his many experimental investigations and discoveries. Ultimately, these led to his astonishing insights published in De Mortu Cordis in 1628 which changed the understanding of the cardio-vascular system forever.

An Efficient Method for the Preparative Isolation and Purification of Flavonoids from Leaves of Crataegus pinnatifida by HSCCC and Pre-HPLC.

PubMed

Wen, Lei; Lin, Yunliang; Lv, Ruimin; Yan, Huijiao; Yu, Jinqian; Zhao, Hengqiang; Wang, Xiao; Wang, Daijie

2017-05-09

In this work, flavonoid fraction from the leaves of Crataegus pinnatifida was separated into its seven main constituents using a combination of HSCCC coupled with pre-HPLC. In the first step, the total flavonoid extract was subjected to HSCCC with a two-solvent system of chloroform/methanol/water/ n -butanol (4:3:2:1.5, v/v ), yielding four pure compounds, namely (-)-epicatechin ( 1 ), quercetin-3- O -(2,6-di-α-l-rhamnopyranosyl)-β-d-galactopyranoside ( 2 ), 4''- O -glucosylvitexin ( 3 ) and 2''- O -rhamnosylvitexin ( 4 ) as well as a mixture of three further flavonoids. An extrusion mode was used to rapidly separate quercetin-3- O -(2,6-di-α-l-rhamnopyranosyl)-β-d-galactopyranoside with a big K D -value. In the second step, the mixture that resulted from HSCCC was separated by pre-HPLC, resulting in three pure compounds including: vitexin ( 5 ), hyperoside ( 6 ) and isoquercitrin ( 7 ). The purities of the isolated compounds were established to be over 98%, as determined by HPLC. The structures of these seven flavonoids were elucidated by ESI-MS and NMR spectroscopic analyses.

Productivity Improvements in U.S. Naval Shipbuilding

DTIC Science & Technology

1982-01-01

Bennett ANADAC, Inc. Charles A. Bookman, Marine Board National Academy of Sciences Thomas F. Bridges John J. McMullen Associates, Inc. Harvey E...Donald Kerlin U.S. Coast Guard Frank R. Kesterman Rhode Island Hospital Trust National Bank John F. Kimble M. W. Kellogg Company Ronald Kiss...vn^::, 11 NAVY SHIPBUILDING TECHNOLOGY COMMITTEE Robert B. Kurtz, Chairman General Electric (Retired) Fairfield, Connecticut Harvey E. Buffum

[Scientific revolution and embryology: rejection or transformation of antiquity? A comparison between the procreation teachings of Cesare Cremonini, William Harvey und René Descartes].

PubMed

Lo Presti, Roberto

2014-01-01

In this paper I address the issue of the theoretical and epistemological status of embryology at the rise of the so-called "Scientific Revolution" (also in the first half of the seventeenth-century) and raise the question, in what sense and to what extent the historiographical concept of "Scientific Revolution" is applicable to the domain of embryology. To achieve this aim I compare the theories of three protagonists of the medical, scientific and philosophical debate of that age, namely Cesare Cremonini, William Harvey and René Descartes, who had very different views on the world structure and human nature and a very different concept of science, but who shared, as concerns embryological issues, an epigenetic conception of the development of the embryo. Their theories are discussed and compared in light of following questions: 1) What do Cremonini's, Harvey's and Descartes's embryological theories exactly aim to?; 2) In developing their theories, do these thinkers deal explicitly or implicitly with the Aristotelian and the Galenic embryological paradigm?; 3)Do they refer polemically to the Aristotelian and the Galenic tradition and what theoretical and/or rhetorical function have these polemical references?; 4) Do the embryological theories of Cremonini, Harvey and Descartes reflect the century-long dispute between "(Aristotelian) philosophers" and "(Galenic) doctors"?; 5) How is represented embryology as a 'scientific' and/or 'theoretical' domain? And what relationship between concepts of 'truth', 'research', 'tradition' and 'scientific progress' is implied or proposed in the embryological works of these three thinkers? What kind of use do Cremonini, Harvey and Descartes make of the argumenta ex ratione and of those ex experientia?

Hurricane Harvey Riverine Flooding: Part 1 - Reconstruction of Hurricane Harvey Flooding for Harris County, TX using a GPU-accelerated 2D flood model for post-flood hazard analysis

NASA Astrophysics Data System (ADS)

Kalyanapu, A. J.; Dullo, T. T.; Gangrade, S.; Kao, S. C.; Marshall, R.; Islam, S. R.; Ghafoor, S. K.

2017-12-01

Hurricane Harvey that made landfall in the southern Texas this August is one of the most destructive hurricanes during the 2017 hurricane season. During its active period, many areas in coastal Texas region received more than 40 inches of rain. This downpour caused significant flooding resulting in about 77 casualties, displacing more than 30,000 people, inundating hundreds of thousands homes and is currently estimated to have caused more than $70 billion in direct damage. One of the significantly affected areas is Harris County where the city of Houston, TX is located. Covering over two HUC-8 drainage basins ( 2702 mi2), this county experienced more than 80% of its annual average rainfall during this event. This study presents an effort to reconstruct flooding caused by extreme rainfall due to Hurricane Harvey in Harris County, Texas. This computationally intensive task was performed at a 30-m spatial resolution using a rapid flood model called Flood2D-GPU, a graphics processing unit (GPU) accelerated model, on Oak Ridge National Laboratory's (ORNL) Titan Supercomputer. For this task, the hourly rainfall estimates from the National Center for Environmental Prediction Stage IV Quantitative Precipitation Estimate were fed into the Variable Infiltration Capacity (VIC) hydrologic model and Routing Application for Parallel computation of Discharge (RAPID) routing model to estimate flow hydrographs at 69 locations for Flood2D-GPU simulation. Preliminary results of the simulation including flood inundation extents, maps of flood depths and inundation duration will be presented. Future efforts will focus on calibrating and validating the simulation results and assessing the flood damage for better understanding the impacts made by Hurricane Harvey.

Superfund Record of Decision (EPA Region 3): Harvey-Knott Drum site, New Castle County, Delaware, September 1985. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The Harvey-Knott Drum Site is located in New Castle County, Delaware, approximately one-half mile east of the Maryland-Delaware border. The Harvey and Knotts Trucking, Inc., operated an open dump and burning ground on the site between 1963 and 1969. The facility accepted sanitary, municipal, and industrial wastes believed to be sludges, paint pigments, and solvents. Wastes were emptied onto the ground, into excavated trenches, or left in drums (some of which were buried). Some of these wastes were either burned as a means of reducing waste volume, or allowed to seep into the soil. Contamination of soil, surface water, andmore » ground water has occurred as a result of disposal of these industrial wastes. The selected remedial action for this site is included.« less

Changing the Paradigm: Simulation, a Method of First Resort

DTIC Science & Technology

2011-09-01

Environment xvii USAF United States Air Force USD(I) Under Secretary of Defense (Intelligence) V&V Verification and Validation VIC Vector -in...continued use throughout the operations research community, and is perhaps best known from Harvey Wagner’s seminal textbook Principles of Operations...pages 887 and 890 of Harvey Wagner’s seminal textbook Principles of Operations Research (Wagner, 1969). Why was this the paradigm of the time? Was

Spectral Analysis of Breast Cancer on Tissue Microarrays: Seeing Beyond Morphology

DTIC Science & Technology

2005-04-01

Harvey N., Szymanski J.J., Bloch J.J., Mitchell M. investigation of image feature extraction by a genetic algorithm. Proc. SPIE 1999;3812:24-31. 11...automated feature extraction using multiple data sources. Proc. SPIE 2003;5099:190-200. 15 4 Spectral-Spatial Analysis of Urine Cytology Angeletti et al...Appendix Contents: 1. Harvey, N.R., Levenson, R.M., Rimm, D.L. (2003) Investigation of Automated Feature Extraction Techniques for Applications in

Hurricane Harvey's Rapid Wind Intensification seen by NASA's SMAP

NASA Image and Video Library

2017-08-28

The rapid intensification of Hurricane Harvey is seen in this pair of images of ocean surface wind speeds as observed by the radiometer instrument aboard NASA's Soil Moisture Active Passive (SMAP) satellite at 7:29 a.m. CDT Aug. 24th, 2017 (left) and at 7 p.m. CDT Aug. 26th (right). Color indicates wind speed, with red being highest and blue lowest. The images show Harvey's maximum wind speeds increased from approximately 56 miles per hour (25 meters per second) to about 107 miles per hour (47.8 meters per second) in the 36 hours just before landfall. The higher wind speeds estimated near the mouth of the Mississippi River are erroneous and are due to errors in the ancillary sea-surface-salinity data product used by SMAP to estimate extreme wind speeds. https://photojournal.jpl.nasa.gov/catalog/PIA21884

Can We Leverage China to Reduce U.S. Burden in Asia

DTIC Science & Technology

2006-03-07

USAWC STRATEGY RESEARCH PROJECT CAN WE LEVERAGE CHINA TO REDUCE U.S. BURDEN IN ASIA? by Colonel Harvey L. Crockett United States Army Commander...Z39-18 ABSTRACT AUTHOR: Colonel Harvey L. Crockett TITLE: Can We Leverage China to Reduce U.S. Burden in Asia? FORMAT: Strategy Research Project DATE...Education and the Council for Higher Education Accreditation. The views expressed in this student academic research paper are those of the author and

Multijurisdictional Responses to Urban and Regional Disasters.

DTIC Science & Technology

1980-10-30

E C HARVEY DCPA01-79- C -0353 NCLASSFIEO N -"IIIiI."",’ I-I2l IIII EIIIIIIIIIIIIlImIIIIIIIIIIollN NEllll0/I/// I/ I/// 00 MULTIJURISDICTION - C -0...DCPA01-79- C -0353 (SRI International Project HSU-8838) Approved for public release; distribution unlimited. SRI International 333 Ravenswood Avenue Menlo...Report October 1980 Prepared by: M. Mark Earle Thomas W. Fletcher Ernest C . Harvey Charles K. Shafer Prepared for: FEDERAL EMERGENCY MANAGEMENT AGENCY

Rapid-response flood mapping during Hurricanes Harvey, Irma and Maria by the Global Flood Partnership (GFP)

NASA Astrophysics Data System (ADS)

Cohen, S.; Alfieri, L.; Brakenridge, G. R.; Coughlan, E.; Galantowicz, J. F.; Hong, Y.; Kettner, A.; Nghiem, S. V.; Prados, A. I.; Rudari, R.; Salamon, P.; Trigg, M.; Weerts, A.

2017-12-01

The Global Flood Partnership (GFP; https://gfp.jrc.ec.europa.eu) is a multi-disciplinary group of scientists, operational agencies and flood risk managers focused on developing efficient and effective global flood management tools. Launched in 2014, its aim is to establish a partnership for global flood forecasting, monitoring and impact assessment to strengthen preparedness and response and to reduce global disaster losses. International organizations, the private sector, national authorities, universities and research agencies contribute to the GFP on a voluntary basis and benefit from a global network focused on flood risk reduction. At the onset of Hurricane Harvey, GFP was `activated' using email requests via its mailing service. Soon after, flood inundation maps, based on remote sensing analysis and modeling, were shared by different agencies, institutions, and individuals. These products were disseminated, to varying degrees of effectiveness, to federal, state and local agencies via emails and data-sharing services. This generated a broad data-sharing network which was utilized at the early stages of Hurricane Irma's impact, just two weeks after Harvey. In this presentation, we will describe the extent and chronology of the GFP response to both Hurricanes Harvey, Irma and Maria. We will assess the potential usefulness of this effort for event managers in various types of organizations and discuss future improvements to be implemented.

Accessibility assessment of Houston's roadway network during Harvey through integration of observed flood impacts and hydrologic modeling

NASA Astrophysics Data System (ADS)

Gidaris, I.; Gori, A.; Panakkal, P.; Padgett, J.; Bedient, P. B.

2017-12-01

The record-breaking rainfall produced over the Houston region by Hurricane Harvey resulted in catastrophic and unprecedented impacts on the region's infrastructure. Notably, Houston's transportation network was crippled, with almost every major highway flooded during the five-day event. Entire neighborhoods and subdivisions were inundated, rendering them completely inaccessible to rescue crews and emergency services. Harvey has tragically highlighted the vulnerability of major thoroughfares, as well as neighborhood roads, to severe inundation during extreme precipitation events. Furthermore, it has emphasized the need for detailed accessibility characterization of road networks under extreme event scenarios in order to determine which areas of the city are most vulnerable. This analysis assesses and tracks the accessibility of Houston's major highways during Harvey's evolution by utilizing road flood/closure data from the Texas DOT. In the absence of flooded/closure data for local roads, a hybrid approach is adopted that utilizes a physics-based hydrologic model to produce high-resolution inundation estimates for selected urban watersheds in the Houston area. In particular, hydrologic output in the form of inundation depths is used to estimate the operability of local roads. Ultimately, integration of hydrologic-based estimation of road conditions with observed data from DOT supports a network accessibility analysis of selected urban neighborhoods. This accessibility analysis can identify operable routes for emergency response (rescue crews, medical services, etc.) during the storm event.

Comparing residential contamination in a Houston environmental justice neighborhood before and after Hurricane Harvey

PubMed Central

Stone, Kahler W.; Kirsch, Katie R.; Camargo, Krisa; Wade, Terry L.; McDonald, Thomas J.

2018-01-01

Introduction Polycyclic aromatic hydrocarbons (PAHs) are complex environmental toxicants. Exposure to them has been linked to adverse health outcomes including cancer, as well as diseases of the skin, liver, and immune system. Based on an ongoing community engagement partnership with stakeholder groups and residents, we conducted a small longitudinal study to assess domestic exposure to PAHs among residents of Manchester, an environmental justice neighborhood located in the East End of Houston, TX. Methods In December, 2016, we used fiber wipes to collect samples of household dust from 25 homes in Manchester. Following Hurricane Harvey, in September 2017, we revisited 24 of the 25 homes to collect soil samples from the front yards of the same homes. Wipes and soil were analyzed for the presence of PAHs using gas chromatography–mass spectrometry (GC-MS) methods. Principal component analysis plots, heatmaps, and PAH ratios were used to compare pre- and post-Hurricane Harvey samples. Results While direct comparison is not possible, we present three methods for comparing PAHs found in pre-hurricane fiber wipes and post-hurricane soil samples. The methods demonstrate that the PAHs found before and after Hurricane Harvey are likely from similar sources and that those sources are most likely to be associated with combustion. We also found evidence of redistribution of PAHs due to extreme flooding associated with Hurricane Harvey. Discussion Residents of the Manchester neighborhood of Houston, TX, are exposed to a range of PAHs in household dust and outdoor soil. While it was not possible to compare directly, we were able to use several methods to assess detected concentrations, changes in site-specific PAH allocations, and PAH origination. Additional research is needed to identify specific sources of domestic PAH exposure in these communities and continued work involving community members and policy makers should aim to develop interventions to reduce domestic exposure to and prevent negative health outcomes from PAHs. PMID:29420658

Comparing residential contamination in a Houston environmental justice neighborhood before and after Hurricane Harvey

DOE Office of Scientific and Technical Information (OSTI.GOV)

Horney, Jennifer A.; Casillas, Gaston A.; Baker, Erin

Introduction: Polycyclic aromatic hydrocarbons (PAHs) are complex environmental toxicants; exposure to them has been linked to adverse health outcomes including cancer, as well as diseases of the skin, liver, and immune system. Based on an ongoing community engagement partnership with stakeholder groups and residents, we conducted a small longitudinal study to assess domestic exposure to PAHs among residents of Manchester, an environmental justice neighborhood located in the East End of Houston, TX. Methods: In December, 2016, we used fiber wipes to collect samples of household dust from 25 homes in Manchester. Following Hurricane Harvey, in September 2017, we revisited 24more » of the 25 homes to collect soil samples from the front yards of the same homes. Wipes and soil were analyzed for the presence of PAHs using gas chromatography–mass spectrometry (GC-MS) methods. Principle component analysis plots, heatmaps, and PAH ratios were used to compare pre- and post-Hurricane Harvey samples. Results: While direct comparison is difficult, we present three methods for comparing PAHs found in pre-hurricane fiber wipes and post-hurricane soil samples. The methods demonstrate that the PAHs found before and after Hurricane Harvey are likely from similar sources and that those sources are most likely to be associated with combustion. We also found evidence of redistribution of PAHs due to extreme flooding associated with Hurricane Harvey. Discussion: Residents of the Manchester neighborhood of Houston, TX, are exposed to a range of PAHs in household dust and outdoor soil. While difficult to compare directly, we were able to use several methods to assess detected concentrations, changes in site-specific PAH allocations, and PAH origination. Additional research is needed to identify specific sources of domestic PAH exposure in these communities and continued work involving community members and policy makers should aim to develop interventions to reduce domestic exposure to and prevent negative health outcomes from PAHs.« less

Comparing residential contamination in a Houston environmental justice neighborhood before and after Hurricane Harvey.

PubMed

Horney, Jennifer A; Casillas, Gaston A; Baker, Erin; Stone, Kahler W; Kirsch, Katie R; Camargo, Krisa; Wade, Terry L; McDonald, Thomas J

2018-01-01

Polycyclic aromatic hydrocarbons (PAHs) are complex environmental toxicants. Exposure to them has been linked to adverse health outcomes including cancer, as well as diseases of the skin, liver, and immune system. Based on an ongoing community engagement partnership with stakeholder groups and residents, we conducted a small longitudinal study to assess domestic exposure to PAHs among residents of Manchester, an environmental justice neighborhood located in the East End of Houston, TX. In December, 2016, we used fiber wipes to collect samples of household dust from 25 homes in Manchester. Following Hurricane Harvey, in September 2017, we revisited 24 of the 25 homes to collect soil samples from the front yards of the same homes. Wipes and soil were analyzed for the presence of PAHs using gas chromatography-mass spectrometry (GC-MS) methods. Principal component analysis plots, heatmaps, and PAH ratios were used to compare pre- and post-Hurricane Harvey samples. While direct comparison is not possible, we present three methods for comparing PAHs found in pre-hurricane fiber wipes and post-hurricane soil samples. The methods demonstrate that the PAHs found before and after Hurricane Harvey are likely from similar sources and that those sources are most likely to be associated with combustion. We also found evidence of redistribution of PAHs due to extreme flooding associated with Hurricane Harvey. Residents of the Manchester neighborhood of Houston, TX, are exposed to a range of PAHs in household dust and outdoor soil. While it was not possible to compare directly, we were able to use several methods to assess detected concentrations, changes in site-specific PAH allocations, and PAH origination. Additional research is needed to identify specific sources of domestic PAH exposure in these communities and continued work involving community members and policy makers should aim to develop interventions to reduce domestic exposure to and prevent negative health outcomes from PAHs.

How Unusual were Hurricane Harvey's Rains?

NASA Astrophysics Data System (ADS)

Emanuel, K.

2017-12-01

We apply an advanced technique for hurricane risk assessment to evaluate the probability of hurricane rainfall of Harvey's magnitude. The technique embeds a detailed computational hurricane model in the large-scale conditions represented by climate reanalyses and by climate models. We simulate 3700 hurricane events affecting the state of Texas, from each of three climate reanalyses spanning the period 1980-2016, and 2000 events from each of six climate models for each of two periods: the period 1981-2000 from historical simulations, and the period 2081-2100 from future simulations under Representative Concentration Pathway (RCP) 8.5. On the basis of these simulations, we estimate that hurricane rain of Harvey's magnitude in the state of Texas would have had an annual probability of 0.01 in the late twentieth century, and will have an annual probability of 0.18 by the end of this century, with remarkably small scatter among the six climate models downscaled. If the event frequency is changing linearly over time, this would yield an annual probability of 0.06 in 2017.

Assessing cognitive processes related to insomnia: A review and measurement guide for Harvey's cognitive model for the maintenance of insomnia.

PubMed

Hiller, Rachel M; Johnston, Anna; Dohnt, Hayley; Lovato, Nicole; Gradisar, Michael

2015-10-01

Cognitive processes play an important role in the maintenance, and treatment of sleep difficulties, including insomnia. In 2002, a comprehensive model was proposed by Harvey. Since its inception the model has received >300 citations, and provided researchers and clinicians with a framework for understanding and treating insomnia. The aim of this review is two-fold. First, we review the current literature investigating each factor proposed in Harvey's cognitive model of insomnia. Second, we summarise the psychometric properties of key measures used to assess the model's factors and mechanisms. From these aims, we demonstrate both strengths and limitations of the current knowledge of appropriate measurements associated with the model. This review aims to stimulate and guide future research in this area; and provide an understanding of the resources available to measure, target, and resolve cognitive factors that may maintain chronic insomnia. Copyright © 2014 Elsevier Ltd. All rights reserved.

Santiago Ramón y Cajal and Harvey Cushing: two forefathers of neuroscience and neurosurgery.

PubMed

Zamora-Berridi, Grettel J; Pendleton, Courtney; Ruiz, Gabriel; Cohen-Gadol, Aaron A; Quiñones-Hinojosa, Alfredo

2011-11-01

To summarize the extraordinary accomplishments, and the commonalities, between Santiago Ramon y Cajal and Harvey Williams Cushing. Existing literature describing the lives and achievements of Ramón y Cajal and Cushing, as well as personal communication, and the surgical records of the Johns Hopkins Hospital, from 1896 to 1912, were reviewed. Both Ramón y Cajal and Cushing were men of unusually broad interests and talents, and these shared characteristics undoubtedly influenced the career paths and scientific investigations they pursued. Although Santiago Ramón y Cajal and Harvey Williams Cushing never directly interacted, the links between them can be traced through some of their disciples, including Pío del Río Hortega, Wilder Penfield, and Percival Bailey. Ramón y Cajal and Cushing are widely considered the forefathers of neuroscience and neurosurgery, respectively, and their discoveries have made lasting impressions on both the scientific and medical communities. Copyright © 2011 Elsevier Inc. All rights reserved.

Dynamic inundation mapping of Hurricane Harvey flooding in the Houston metro area using hyper-resolution modeling and quantitative image reanalysis

NASA Astrophysics Data System (ADS)

Noh, S. J.; Lee, J. H.; Lee, S.; Zhang, Y.; Seo, D. J.

2017-12-01

Hurricane Harvey was one of the most extreme weather events in Texas history and left significant damages in the Houston and adjoining coastal areas. To understand better the relative impact to urban flooding of extreme amount and spatial extent of rainfall, unique geography, land use and storm surge, high-resolution water modeling is necessary such that natural and man-made components are fully resolved. In this presentation, we reconstruct spatiotemporal evolution of inundation during Hurricane Harvey using hyper-resolution modeling and quantitative image reanalysis. The two-dimensional urban flood model used is based on dynamic wave approximation and 10 m-resolution terrain data, and is forced by the radar-based multisensor quantitative precipitation estimates. The model domain includes Buffalo, Brays, Greens and White Oak Bayous in Houston. The model is simulated using hybrid parallel computing. To evaluate dynamic inundation mapping, we combine various qualitative crowdsourced images and video footages with LiDAR-based terrain data.

Attributable Human-Induced Changes in the Likelihood and Magnitude of the Observed Extreme Precipitation during Hurricane Harvey

DOE PAGES

Risser, Mark D.; Wehner, Michael F.

2017-12-28

Record rainfall amounts were recorded during Hurricane Harvey in the Houston, Texas, area, leading to widespread flooding. We analyze observed precipitation from the Global Historical Climatology Network with a covariate-based extreme value statistical analysis, accounting for both the external influence of global warming and the internal influence of El Niño–Southern Oscillation. We find that human-induced climate change likely increased the chances of the observed precipitation accumulations during Hurricane Harvey in the most affected areas of Houston by a factor of at least 3.5. Further, precipitation accumulations in these areas were likely increased by at least 18.8% (best estimate of 37.7%),more » which is larger than the 6–7% associated with an attributable warming of 1°C in the Gulf of Mexico and Clausius-Clapeyron scaling. Thus, in a Granger causality sense, these statements provide lower bounds on the impact of climate change and motivate further attribution studies using dynamical climate models.« less

Attributable Human-Induced Changes in the Likelihood and Magnitude of the Observed Extreme Precipitation during Hurricane Harvey

DOE Office of Scientific and Technical Information (OSTI.GOV)

Risser, Mark D.; Wehner, Michael F.

Record rainfall amounts were recorded during Hurricane Harvey in the Houston, Texas, area, leading to widespread flooding. We analyze observed precipitation from the Global Historical Climatology Network with a covariate-based extreme value statistical analysis, accounting for both the external influence of global warming and the internal influence of El Niño–Southern Oscillation. We find that human-induced climate change likely increased the chances of the observed precipitation accumulations during Hurricane Harvey in the most affected areas of Houston by a factor of at least 3.5. Further, precipitation accumulations in these areas were likely increased by at least 18.8% (best estimate of 37.7%),more » which is larger than the 6–7% associated with an attributable warming of 1°C in the Gulf of Mexico and Clausius-Clapeyron scaling. Thus, in a Granger causality sense, these statements provide lower bounds on the impact of climate change and motivate further attribution studies using dynamical climate models.« less

Attributable Human-Induced Changes in the Likelihood and Magnitude of the Observed Extreme Precipitation during Hurricane Harvey

NASA Astrophysics Data System (ADS)

Risser, Mark D.; Wehner, Michael F.

2017-12-01

Record rainfall amounts were recorded during Hurricane Harvey in the Houston, Texas, area, leading to widespread flooding. We analyze observed precipitation from the Global Historical Climatology Network with a covariate-based extreme value statistical analysis, accounting for both the external influence of global warming and the internal influence of El Niño-Southern Oscillation. We find that human-induced climate change likely increased the chances of the observed precipitation accumulations during Hurricane Harvey in the most affected areas of Houston by a factor of at least 3.5. Further, precipitation accumulations in these areas were likely increased by at least 18.8% (best estimate of 37.7%), which is larger than the 6-7% associated with an attributable warming of 1°C in the Gulf of Mexico and Clausius-Clapeyron scaling. In a Granger causality sense, these statements provide lower bounds on the impact of climate change and motivate further attribution studies using dynamical climate models.

Sequential Excitation Preparation of Molecular Energy Levels with Special Structural and Chemical Properties.

DTIC Science & Technology

1986-01-06

D.E. Reisner, and P.H. Vaccaro, pp. 393-404 in Lasers as Reactants and Probes in Chemistry, (eds. W.M. Jackson and A.B. Harvey) Howard University Press...as Reactants and Probes in Chemistry, Howard University (May 1982). 4. J.L. Kinsey, "An Outsider’s View of the Spectroscopy of Polyatomic Systems...Kinsey, C. Kittrell, D.E. Reisner, and P.H. Vaccaro, pp. 393-404 in Lasers as Reactants and Probes in Chemistry (eds. W.M. Jackson and A.B. Harvey), Howard

Losing the Quality Battle in Australian Education for Librarianship: A Decade on. (An Update on the Original Article by Ross Harvey, "Losing the Quality Battle in Australian Education for Librarianship". "The Australian Library Journal", 50 No. 1, 2001: 15-22.)

ERIC Educational Resources Information Center

Harvey, Ross

2011-01-01

The Editor of "ALJ" has invited me to comment on my 2001 article "Losing the quality battle in Australian education for librarianship" (Harvey 2001). The article was prompted by a period I spent as a visiting professor in the Department of Information Studies at UCLA (the University of California Los Angeles) and was written while I was there.…

Chlorogenic Acid from Hawthorn Berry (Crataegus pinnatifida Fruit) Prevents Stress Hormone-Induced Depressive Behavior, Through Monoamine Oxidase B-reactive Oxygen Species Signaling in Hippocampal Astrocytes of Mice.

PubMed

Lim, Dong Wook; Han, Taewon; Jung, Jonghoon; Song, Yuri; Um, Min Young; Yoon, Minseok; Kim, Yun Tai; Cho, Seungmok; Kim, In-Ho; Han, Daeseok; Lee, Changho; Lee, Jaekwang

2018-06-12

Oxidative stress has been implicated in mental disorders, including depression. Chlorogenic acid (CGA), a phenolic compound abundant in herbs and fruits, has been reported to have antioxidant and free-radical scavenging properties. In this study, we investigated the antidepressant-like effects and active mechanisms of CGA from the extract of Crataegus pinnatifida (CP) fruit. Depression-like phenotypes were induced in mice by daily injection of stress hormone for 1-2 weeks. The brains of these animals exhibited reduced brain-derived neurotrophic factor (BDNF) expression and increased astrocytic hypertrophy, which are typical markers of depression in animal models. Stress hormone injection 1) upregulated monoamine oxidase B (MAOB) expression and 2) reduced spine numbers along neuronal dendrites, which indicates synaptic depression. The oral administration of CGA (30 mg/kg) or CP (300 mg/kg) prevented MAOB activation following reactive oxygen species (ROS) production and had an ameliorative effect on depressive behavioral tests (e.g., tail suspension and forced swim tests). In vitro assays performed on cultured C8-D1A cells revealed that CGA and CP inhibited MAOB activity and ROS production. Our study indicates that CGA and CP extracts prevented depressive behavior and thereby have potential as natural antidepressants. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

The dynamics underlying the regeneration and stalling of Hurricane Harvey

NASA Astrophysics Data System (ADS)

Liang, X. S.

2017-12-01

The explosive regeneration and stalling make the hurricane Harvey go from a little-noticed storm to an extremely destructive behemoth in late August 2017 that incurred an estimated economic loss at 70-200 billion USD. In this study, we use a recently developed analysis tool, namely, multiscale window transform (MWT), and the MWT-based theory of canonical transfer, to investigate the dynamics underlying this regeneration and stalling. The atmospheric fields are reconstructed onto three scale ranges or windows, namely, large-scale, tropical cyclone-scale, and cumulus convection-scale windows. The intertwined cyclone-scale nonlinear energy process is uniquely separated into a transport of energy within the cyclone window and an interscale transfer through reconstructing the "atomic" energy fluxes on the multiple scale windows. The resulting transfer bears a Lie bracket form, reminiscent of the Poisson bracket in Hamiltonian mechanics, and is hence referred to as canonical. It is found that within the Gulf of Mexico, Harvey gains much energy from the cumulus convection window through an inverse energy cascade, leading to its explosive growth. In the mean time, there is a barotropic instability (positive canonical transfer) center of the mean circulation in the lower and mid troposphere which lies quasi-steadily over Houston during August 22 through early September. The northwestward propagating Harvey meets that center and then stalls for two days near the coastline, dropping torrential and unprecedented amounts of rainfall and causing catastrophic flooding. It moves out of the instability center by the end of August, and then dissipates quickly in the following days.

Harvey Butcher: a passion for astronomical instrumentation

NASA Astrophysics Data System (ADS)

Bhathal, Ragbir

2014-11-01

This paper covers some aspects of the scientific life of Harvey Butcher who was the Director of the Research School for Astronomy and Astrophysics at the Australian National University in Canberra from September 2007 to January 2013. He has made significant contributions to research on the evolution of galaxies, nucleosynthesis, and on the design and implementation of advanced astronomical instrumentation including LOFAR (Low Frequency Array Radio telescope). He is well known for his discovery of the Butcher-Oemler effect. Before coming to Australia he was the Director of the Netherlands Foundation for Research in Astronomy from September 1991 to January 2007. In 2005 he was awarded a Knighthood in the Order of the Netherlands Lion for contributions to interdisciplinary science, innovation and public outreach.This paper is based on an interview conducted by the author with Harvey Butcher for the National Project on Significant Australian Astronomers sponsored by the National Library of Australia. Except otherwise stated, all quotations used in this paper are from the Butcher interview which has been deposited in the Oral History Archives of the National Library.

Approximate solution to the Callan-Giddings-Harvey-Strominger field equations for two-dimensional evaporating black holes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ori, Amos

2010-11-15

Callan, Giddings, Harvey, and Strominger (CGHS) previously introduced a two-dimensional semiclassical model of gravity coupled to a dilaton and to matter fields. Their model yields a system of field equations which may describe the formation of a black hole in gravitational collapse as well as its subsequent evaporation. Here we present an approximate analytical solution to the semiclassical CGHS field equations. This solution is constructed using the recently introduced formalism of flux-conserving hyperbolic systems. We also explore the asymptotic behavior at the horizon of the evaporating black hole.

Hurricane Harvey Flooding Seen in New NASA Satellite Image

NASA Image and Video Library

2017-09-05

On Sept. 5, 2017, the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) instrument on NASA's Terra spacecraft captured this image of the area around Bay City, Texas, about 50 miles (80 kilometers) southwest of Houston. Hurricane Harvey caused extensive inland flooding, seen as dark blue areas where the water is relatively clear, and green-grey where the water carries sediment. The image covers an area of 32 by 65 miles (52 by 105 kilometers), and is centered at 29.2 degrees north, 95.8 degrees west. https://photojournal.jpl.nasa.gov/catalog/PIA21940

Brief communication: Loss of life due to Hurricane Harvey

NASA Astrophysics Data System (ADS)

Jonkman, Sebastiaan N.; Godfroy, Maartje; Sebastian, Antonia; Kolen, Bas

2018-04-01

An analysis was made of the loss of life caused by Hurricane Harvey. Information was collected for 70 fatalities that occurred due to the event and were recovered within the first 2 weeks after landfall. Most fatalities occurred due to drowning (81 %), particularly in and around vehicles. Males (70 %) and people over 50 years old (56 %) were overrepresented in the dataset. More than half of the fatalities occurred in the greater Houston area (n = 37), where heavy rainfall and dam releases caused unprecedented urban flooding. The majority of fatalities were recovered outside the designated 100- and 500-year flood hazard areas.

Centennial ties: Harvey Cushing (1869-1939) and William Osler (1849-1919) on Andreas Vesalius (1514-1564).

PubMed

Toodayan, Nadeem

2017-08-01

Andreas Vesalius is often regarded as the founding father of modern anatomical study. The quincentennial anniversary of his birth - 31 December 2014 - has been very widely commemorated, and it is the purpose of this article to contrast these celebrations with what happened during the Vesalius quatercentenary year of 1914. More specifically, we look at how Vesalius was perceived a century ago by examining his influence on two of western medicine's most iconic gentlemen - Harvey Williams Cushing (1869-1939) and his larger than life mentor, Sir William Osler (1849-1919).

How Investment in #GovTech Tools Helped with USGS Disaster Response During Hurricane Harvey

NASA Astrophysics Data System (ADS)

Shah, S.; Pearson, D. K.

2017-12-01

Hurricane Harvey was an unprecedented storm event that not only included a challenge to decision-makers, but also the scientific community to provide clear and rapid dissemination of changing streamflow conditions and potential flooding concerns. Of primary importance to the U.S. Geological Survey (USGS) Texas Water Science Center was to focus on the availability of accessible data and scientific communication of rapidly changing water conditions across Texas with regards to heavy rainfall rates, rising rivers, streams, and lake elevations where USGS has monitoring stations. Infrastructure modernization leading to advanced GovTech practices and data visualization was key to the USGS role in providing data during Hurricane Harvey. In the last two years, USGS has released two web applications, "Texas Water Dashboard" and "Water-On-The-Go", which were heavily utilized by partners, local media, and municipal government officials. These tools provided the backbone for data distribution through both desktop and mobile applications as decision support during flood events. The combination of Texas Water Science Center web tools and the USGS National Water Information System handled more than 5-million data requests over the course of the storm. On the ground local information near Buffalo Bayou and Addicks/Barker Dams, as well as statewide support of USGS real-time scientific data, were delivered to the National Weather Service, U.S. Army Corps of Engineers, FEMA, Harris County Flood Control District, the general public, and others. This presentation will provide an overview of GovTech solutions used during Hurricane Harvey, including the history of USGS tool development, discussion on the public response, and future applications for helping provide scientific communications to the public.

Mapping Daily and Maximum Flood Extents at 90-m Resolution During Hurricanes Harvey and Irma Using Passive Microwave Remote Sensing

NASA Astrophysics Data System (ADS)

Galantowicz, J. F.; Picton, J.; Root, B.

2017-12-01

Passive microwave remote sensing can provided a distinct perspective on flood events by virtue of wide sensor fields of view, frequent observations from multiple satellites, and sensitivity through clouds and vegetation. During Hurricanes Harvey and Irma, we used AMSR2 (Advanced Microwave Scanning Radiometer 2, JAXA) data to map flood extents starting from the first post-storm rain-free sensor passes. Our standard flood mapping algorithm (FloodScan) derives flooded fraction from 22-km microwave data (AMSR2 or NASA's GMI) in near real time and downscales it to 90-m resolution using a database built from topography, hydrology, and Global Surface Water Explorer data and normalized to microwave data footprint shapes. During Harvey and Irma we tested experimental versions of the algorithm designed to map the maximum post-storm flood extent rapidly and made a variety of map products available immediately for use in storm monitoring and response. The maps have several unique features including spanning the entire storm-affected area and providing multiple post-storm updates as flood water shifted and receded. From the daily maps we derived secondary products such as flood duration, maximum flood extent (Figure 1), and flood depth. In this presentation, we describe flood extent evolution, maximum extent, and local details as detected by the FloodScan algorithm in the wake of Harvey and Irma. We compare FloodScan results to other available flood mapping resources, note observed shortcomings, and describe improvements made in response. We also discuss how best-estimate maps could be updated in near real time by merging FloodScan products and data from other remote sensing systems and hydrological models.

Using integrated modeling for generating watershed-scale dynamic flood maps for Hurricane Harvey

NASA Astrophysics Data System (ADS)

Saksena, S.; Dey, S.; Merwade, V.; Singhofen, P. J.

2017-12-01

Hurricane Harvey, which was categorized as a 1000-year return period event, produced unprecedented rainfall and flooding in Houston. Although the expected rainfall was forecasted much before the event, there was no way to identify which regions were at higher risk of flooding, the magnitude of flooding, and when the impacts of rainfall would be highest. The inability to predict the location, duration, and depth of flooding created uncertainty over evacuation planning and preparation. This catastrophic event highlighted that the conventional approach to managing flood risk using 100-year static flood inundation maps is inadequate because of its inability to predict flood duration and extents for 500-year or 1000-year return period events in real-time. The purpose of this study is to create models that can dynamically predict the impacts of rainfall and subsequent flooding, so that necessary evacuation and rescue efforts can be planned in advance. This study uses a 2D integrated surface water-groundwater model called ICPR (Interconnected Channel and Pond Routing) to simulate both the hydrology and hydrodynamics for Hurricane Harvey. The methodology involves using the NHD stream network to create a 2D model that incorporates rainfall, land use, vadose zone properties and topography to estimate streamflow and generate dynamic flood depths and extents. The results show that dynamic flood mapping captures the flood hydrodynamics more accurately and is able to predict the magnitude, extent and time of occurrence for extreme events such as Hurricane Harvey. Therefore, integrated modeling has the potential to identify regions that are more susceptible to flooding, which is especially useful for large-scale planning and allocation of resources for protection against future flood risk.

Application of alkyl polyglycoside surfactant in ultrasonic-assisted extraction followed by macroporous resin enrichment for the separation of vitexin-2″-O-rhamnoside and vitexin from Crataegus pinnatifida leaves.

PubMed

Han, Feng; Guo, Yupin; Gu, Huiyan; Li, Fenglan; Hu, Baozhong; Yang, Lei

2016-02-15

An alkyl polyglycoside (APG) surfactant was used in ultrasonic-assisted extraction to effectively extract vitexin-2″-O-rhamnoside (VOR) and vitexin (VIT) from Crataegus pinnatifida leaves. APG0810 was selected as the surfactant. The extraction process was optimized for ultrasonic power, the APG concentration, ultrasonic time, soaking time, and liquid-solid ratio. The proposed approach showed good recovery (99.80-102.50% for VOR and 98.83-103.19% for VIT) and reproducibility (relative standard deviation, n=5; 3.7% for VOR and 4.2% for VIT) for both components. The proposed sample preparation method is both simple and effective. The use of APG for extraction of key herbal ingredients shows great potential. Ten widely used commercial macroporous resins were evaluated in a screening study to identify a suitable resin for the separation and purification of VOR and VIT. After comparing static and dynamic adsorption and desorption processes, HPD100B was selected as the most suitable resin. After column adsorption and desorption on this resin, the target compounds VOR and VIT can be effectively separated from the APG0810 extraction solution. Recoveries of VOR and VIT were 89.27%±0.42% and 85.29%±0.36%, respectively. The purity of VOR increased from 35.0% to 58.3% and the purity of VIT increased from 12.5% to 19.9%. Copyright © 2016 Elsevier B.V. All rights reserved.

Decrease of blood lipids induced by Shan-Zha (fruit of Crataegus pinnatifida) is mainly related to an increase of PPARα in liver of mice fed high-fat diet.

PubMed

Niu, C- S; Chen, C- T; Chen, L- J; Cheng, K- C; Yeh, C- H; Cheng, J- T

2011-08-01

Hyperlipidemia is an important risk factor for cardiovascular diseases. Agents for the treatment of hyperlipidemia are well-developed in the clinic while PPARα is a target for lipid-lowering agents. Shan-Zha (Crataegus pinnatifida) is a traditional Chinese medicine used to increase digestion. Also, Shan-Zha fruit extract showed merit to improve obesity and hyperlipidemia in hamsters; however, the mechanism remained obscure. In the present study, hypertriglycemia and hypercholesterolemia were induced by high fat diet in C57BL/6 J male mice. Then, they were orally administered with Shan-Zha fruit extract at an effective dose of 250 mg/kg for 7 days. The liver was removed to estimate the expressions of PPARα and β-oxidation-related enzyme. Oral intake of Shan-Zha extract significantly improved hyperlipidemia in high fat diet-fed mice with an increase of PPARα expression in liver. Also, expression of PPARα-regulated β-oxidation-related enzymes was raised in liver by Shan-Zha extract. However, adipose tissue and others were not modified by this treatment of Shan-Zha fruit extract. Thus, Shan-Zha can increase the expression of PPARα to facilitate β-oxidation-related enzymes in liver for lipid degradation and blood lipid decrement. Also, this is the first report showing Shan-Zha fruit extract can influence liver to lower hyperlipidemia prior to the action in adipose tissue. Georg Thieme Verlag KG Stuttgart · New York.

A diet formula of Puerariae radix, Lycium barbarum, Crataegus pinnatifida, and Polygonati rhizoma alleviates insulin resistance and hepatic steatosis in CD-1 mice and HepG2 cells.

PubMed

Liu, Jia; Zhang, HongJuan; Ji, BaoPing; Cai, ShengBao; Wang, RuoJun; Zhou, Feng; Yang, JunSi; Liu, HuiJun

2014-05-01

According to the principles of traditional Chinese medicine, medicinal and edible herbs exhibit holistic effects through their actions on multiple target organs. Four herbs, Puerariae radix, Lycium barbarum, Crataegus pinnatifida, and Polygonati rhizoma, were selected and combined to create a new herbal formula (PLCP). The protective effects of both the aqueous extract (AE) and ethanol extract (EE) of PLCP against insulin resistance (IR) and non-alcoholic fatty liver disease (NAFLD) were evaluated in both high fat and high fructose diet-fed mice. Active fractions and constituents were screened in HepG2 cells with IR or an over-accumulation of triglycerides, and were further identified by high-performance liquid chromatography/electrospray ionization/mass spectrometry. The results indicate that the AE did not improve (p > 0.05) glucose tolerance after three weeks, whereas EE showed a promising effect throughout the experiment. Medium and high doses of EE were found to reduce fasting blood glucose at week 9 by 21.1% and 24.4%, respectively. In addition, their efficacies for alleviating IR were comparable with that of metformin. Compared with AE, EE effectively improved hyperlipidemia, antioxidant status, and NAFLD. In contrast, metformin did not alleviate hyperlipidemia (p > 0.05) or NAFLD in the mice model. Results from the cell-based study indicate that the protective effects of EE were possibly due to the actions from puerarin, 3'-methoxypuerarin, daidzin, daidzein, and ononin.

Single speckle SRS threshold as determined by electron trapping, collisions and speckle duration

NASA Astrophysics Data System (ADS)

Rose, Harvey; Daughton, William; Yin, Lin; Langdon, Bruce

2008-11-01

Speckle SRS intensity threshold has been shown to increase with spatial dimension, D, because both diffraction and trapped electron escape rate increase with D, though the net effect is to substantially decrease the threshold compared to 1D linear gain calculations. On the other hand, the apparent threshold appears to decrease with integration time in PIC simulations. We present an optimum nonlinearly resonant calculation of the SRS threshold, taking into account large fluctuations of the SRS seed reflectivity, R0. Such fluctuations, absent in 1D, are caused by a gap in the linear reflectivity gain spectrum which leads to an exponential probability distribution for R0. While the SRS threshold intensity is of course finite, these fluctuations lead to a decrease of apparent threshold with increasing speckle lifetime. L. Yin et al., Physics of Plasmas 15, 013109 (2008). D. S. Montgomery et al., 9, 2311(2002). Bruce Langdon et al., 38^th Anomalous Absorption Conference (2008). Harvey A. Rose, Physics of Plasmas 10, 1468 (2003). Harvey A. Rose and L. Yin, Physics of Plasmas 15, 042311 (2008)., Harvey A. Rose and David A. Russell, Phys. Plasma 8, 4784 (2001).

[Cardiology was born with the modern medical science].

PubMed

de Micheli, Alfredo

2015-01-01

Modern medical science was born in the post-Renaissance age and began to consolidate towards the middle of the XVII century thanks to physicists, physiologists and biologists, most of whom were direct or indirect pupils of Galileo. The discovery of blood circulation by Harvey is now considered the only progress in physiology at the beginning of the XVII century, comparable to the current advances seen in physical sciences. The history of this exploit could be written from view point of the progressive advance in knowledge. In his experiments, Harvey referred to the authentic not imaginary experiments, and put forward irrefutable quantitative arguments. We can therefore claim that his discovery of blood circulation was the first proper explanation of an organic process and the starting point leading to experimental physiology. So it seems justified to assert that modern medical science did not all rise suddenly, but was gradually structured starting from the middle of the XVII century following the path traced by William Harvey in light of Galileo's thought. Copyright © 2014 Instituto Nacional de Cardiología Ignacio Chávez. Published by Masson Doyma México S.A. All rights reserved.

A new species of Xystonotus Wolcott, 1900 (Acari, Hydrachnidia, Mideopsidae) from bromeliad phytotelmata in Brazilian Atlantic rainforest.

PubMed

Pešić, Vladimir; Piccoli, Gustavo Cauê De Oliveira; Araújo, Marcel Santos De; Rezende, José Marcos; Gonçalves, Ana Zangirolame

2015-07-02

The rosette architecture of some bromeliad species traps water and organic matter from the canopy in leaf axils (forming phytotelmata) and harbors many species of invertebrate animals (Frank & Lounibos 2009). Some water mites are adapted to live in phytotelmata; typically recorded from water-filled tree holes, bromeliad tanks, and a range of plant axils. Karl Viets (1939) was the first acarologist who discovered Micruracaropsis phytotelmaticola (Viets, 1939) in the water contained in the leaf bases of epiphytic Bromeliaceae in Surinam. Later on, Orghidan et al. (1977) described Arrenurus bromeliacearum Orghidan, Gruia & Viña Bayés, 1977 from phytotelmata in Cuba. Orghidan & Gruia (1987) reported Arrenurus andrewfieldi Orghidan & Gruia, 1983 from phytotelmata of epiphytic bromeliad Vriesea platynema in Venezuela. Smith & Harvey (1989) described Arrenurus kitchingi Smith & Harvey, 1989 from water-filled tree holes in Queensland, Australia. The same authors (Smith & Harvey 1989) also reported that members of genus Thyopsis occur in water-filled tree holes in Ohio, USA. Rosso de Ferradás & Fernández (2001) reported two Arrenurus species from water accumulated in Guzmania mucronata (Bromeliaceae) in Venezuela, A. andrewfieldi Orghidan & Gruia, 1983 and A. caquetiorum Rosso de Ferradás & Fernández, 2001.

Better Data Help Make Better Decisions: Disseminating Information During Hurricane Harvey

NASA Astrophysics Data System (ADS)

Conner, K.; Lindner, J.; Moore, M.

2017-12-01

During large scale natural disasters, like hurricane Harvey, time-critical decisions are made on a constant basis. From evacuation orders, allocation of emergency resources, or allowing people to return home, decisions are only as good as the information upon which they are based. Better real-time data lead to better decisions which ultimately leads to improved disaster response and recovery. In 2015 Harris County Flood Control District (HCFCD) in Houston, TX began upgrading their automatic flood warning system (FWS) that dates back to the 1980s. The HCFCD network consists of 154 remote stations that report precipitation intensities and stream levels in near real time. Since the upgrades were completed in 2016 the Houston area has experienced multiple 100+ rain events, the most recent being Hurricane Harvey. The FWS generated accurate, reliable, real-time data throughout the entirety of the record breaking, four-day event. This information was disseminated to state, local and federal agencies, news outlets and the public via web sites and social media. Without this quality of data, disaster management decisions could not have been made effectively, ultimately leading to greater destruction of property and loss of life.

Did Harvey Learn from Katrina? Initial Observations of the Response to Companion Animals during Hurricane Harvey.

PubMed

Glassey, Steve

2018-03-30

The aftermath of Hurricane Katrina in 2005 became the genesis of animal emergency management and created significant reforms in the US particularly the passage of the Pets Emergency and Transportation Standards Act in 2006 that required state and local emergency management arrangements to be pet- and service animal-inclusive. More than a decade later Hurricane Harvey struck the Gulf states with all 68 directly related deaths occurring in the state of Texas. In this study, six key officials involved in the response underwent a semi-structured interview to investigate the impact of the PETS Act on preparedness and response. Though the results have limitations due to the low sample size, it was found that the PETS Act and the lessons of Hurricane Katrina had contributed to a positive cultural shift to including pets (companion animals) in emergency response. However, there was a general theme that plans required under the PETS Act were under-developed and many of the animal response lessons from previous emergencies remain unresolved. The study also observed the first empirical case of disaster hoarding which highlights the need for animal law enforcement agencies to be active in emergency response.

Evaluation of a small beach nourishment project to enhance habitat suitability for horseshoe crabs

USGS Publications Warehouse

Jackson, N.L.; Smith, D.R.; Tiyarattanachai, R.; Nordstrom, K.F.

2007-01-01

This field study evaluates the effect of nourishing an estuarine beach with gravel to enhance spawning rates by horseshoe crabs. A total of 564??m3 of coarse sand and gravel were emplaced in two 90??m-long treatment segments at Bowers Beach, Delaware, USA from 9 to 11 April 2002. Field data were gathered between 6 April and 24 May 2002 to characterize the two fill segments and the un-nourished segments between them as well as two control segments at the adjacent Ted Harvey Beach. Sediment samples were taken from the foreshore surface and at depth before and after the nourishment. Bay water levels, wave heights, and beach ground water characteristics were monitored over a 12-hour tidal cycle at one of the nourished (15 May 2002) and the unnourished segment (16 May 2002) at Bowers Beach and at one of the control segments at Ted Harvey Beach (21 May 2002) using piezometers and pressure transducers inserted in wells. The beaches were cored to estimate the density of horseshoe crab eggs deposited during the spawning season. Horseshoe crab eggs were buried in pouches at 0.15 to 0.20??m depth for 30 to 40??days to evaluate their survival in developing into embryo or larval stage. Bulk sediment samples were taken to evaluate moisture characteristics near locations where egg pouches were buried. Density of spawning females at Bowers Beach was 1.04??m- 2 in 2001 and 1.20??m- 2 in 2002. These rates are lower than at Ted Harvey Beach but reveal an increase in spawning while Ted Harvey Beach underwent a considerable decrease (2.63??m- 2 to 1.35??m- 2). Sediments low on the foreshore remained nearly saturated throughout the tidal cycle at both beaches. The average hydraulic conductivity on the upper foreshore at the non-treatment section at Bowers Beach (0.19??cm s- 1) was less than at Ted Harvey Beach (0.27??cm s- 1), and the finer, better sorted sediments at depth at Bowers Beach resulted in a higher porosity, creating greater moisture retention potential. Egg development was greatest at mid foreshore at all sites. Eggs at the lower foreshore elevation remained viable, but did not develop to the embryo stage. Between-beach differences were limited to high elevations where higher mortality occurred at Ted Harvey Beach due to desiccation. Adding small amounts of gravel to a sand beach may change the appearance of the surface but may not appreciably increase mean grain size and sorting at depth or the hydraulic conductivity over the spawning season. The pebble fraction may be important for site selection, but finer sizes may be more important for egg survival because of moisture retention. ?? 2006 Elsevier B.V. All rights reserved.

The burdens-benefits ratio consideration for medical administration of nutrition and hydration to persons in the persistent vegetative state.

PubMed

Harvey, John C

2006-04-01

In this article, Harvey notes the initial confusion about the statement made by the pope concerning artificial nutrition and hydration on patients suffering persistent vegetative states (PVS) due to misunderstanding through the translation of the pope's words. He clarifies and assesses what was meant by the statement. He also discusses the problems of terminology concerned with the subject of PVS. Harvey concludes that the papal allocution was in line with traditional Catholic bioethics, and that while maintaining the life of a patient is favorable, in particular cases this presumption wanes when it is clear that this treatment modality would be futile or very burdensome.

[The discovery of blood circulation: revolution or revision?].

PubMed

Crignon, Claire

2011-01-01

The discovery of the principle of blood circulation by William Harvey is generally considered as one of the major events of the "scientific revolution" of the 17th century. This paper reconsiders the question by taking in account the way Harvey's discovery was discussed by some contemporary philosophers and physicians, in particular Fontenelle, who insisted on the necessity of redefining methods and principles of medical knowledge, basing themselves on the revival of anatomy and physiology, and of its consequences on the way it permits to think about the human nature. This return allows us to consider the opportunity of substituting the kuhnian scheme of "structure of scientific revolutions" for the bachelardian concept of "refonte".

Assessing the present and future probability of Hurricane Harvey's rainfall

NASA Astrophysics Data System (ADS)

Emanuel, Kerry

2017-11-01

We estimate, for current and future climates, the annual probability of areally averaged hurricane rain of Hurricane Harvey's magnitude by downscaling large numbers of tropical cyclones from three climate reanalyses and six climate models. For the state of Texas, we estimate that the annual probability of 500 mm of area-integrated rainfall was about 1% in the period 1981–2000 and will increase to 18% over the period 2081–2100 under Intergovernmental Panel on Climate Change (IPCC) AR5 representative concentration pathway 8.5. If the frequency of such event is increasingly linearly between these two periods, then in 2017 the annual probability would be 6%, a sixfold increase since the late 20th century.

Wind-related resuspension of sediments in the Peel-Harvey Estuarine System

NASA Astrophysics Data System (ADS)

Gabrielson, J. O.; Lukatelich, R. J.

1985-02-01

Resuspension of bottom sediments accounted for 69-92% of mean deposition rates (11·6-69·3 gm -2 day -1) measured at 5 sites in the Peel-Harvey Estuarine System, Western Australia. Deposition rates at all but one of the sites were found to be correlated ( P<0·05) with a function of wind combining a fetch factor with the number of hours of winds greater than 5 ms -1 weighted by the third power of wind velocity. The exception was the only site with a cover of benthic algae ( Cladophora) during the study. Wind-related resuspension greatly affects the forms and amounts of productivity in this system.

Harvey Cushing at Johns Hopkins.

PubMed

Long, D M

1999-11-01

Harvey Cushing began surgical training with William Halsted at Johns Hopkins in 1896. Cushing joined the Johns Hopkins faculty in 1900 and spent 1 year in Europe in the laboratory of Theodore Kocher. He returned to Johns Hopkins, where he founded neurosurgery as an independent specialty, established the concept of the clinician scientist, discovered the hormonal properties of the pituitary gland and founded endocrinology, introduced intraoperative x-rays into surgical practice, introduced blood pressure monitoring into the operating room, and wrote the first definitive text on neurosurgery. Although there have been many pioneers in our field, Cushing, more than anyone else, developed neurosurgery as a specialty and left a legacy of talented neurosurgeons to develop and expand the field.

Potential hepatoprotective effects of new Cuban natural products in rat hepatocytes culture.

PubMed

Rodeiro, I; Donato, M T; Martínez, I; Hernández, I; Garrido, G; González-Lavaut, J A; Menéndez, R; Laguna, A; Castell, J V; Gómez-Lechón, M J

2008-08-01

The protective effects of five Cuban natural products (Mangifera indica L. (MSBE), Erythroxylum minutifolium, Erythroxylum confusum, Thalassia testudinum and Dictyota pinnatifida extracts and mangiferin) on the oxidative damage induced by model toxicants in rat hepatocyte cultures were studied. Cells were pre-incubated with the natural products (5-200 microg/mL) for 24 h. Then hepatotoxins (tert-butyl hydroperoxide, ethanol, carbon tetrachloride and lipopolysaccharide) were individually added and post-incubated for another 24 h. After treatments, cell viability was determined using the MTT assay. Mangiferin and MSBE exhibited the highest cytoprotective potential (EC50 between 50 and 125 microg/mL), followed by T. testudinum and Erythroxylum extracts, whereas no significant protective effects was produced by Dictyota extract treatment. Antioxidant properties of the natural products against lipid peroxidation and GSH depletion induced by tert-butyl hydroperoxide were then investigated. The results show that at 36 h pre-treatment of cells with mangiferin or MSBE, concentrations of T. testudinum and Erythroxylum extracts ranging from 25 to 100 microg/mL significantly inhibited lipid peroxidation induced by tert-butyl hydroperoxide (100 and 250 microM) and increased the GSH levels reduced by the toxicant. D. pinnatifida inhibited lipid peroxidation, but did not preserve GSH levels. In conclusion, MSBE, E. minutifolium, E. confusum and T. testudinum extracts and mangiferin showed hepatoprotective activity against induced damage in all the experimental series, where mangiferin and the extracts of MSBE and T. testudinum were the best candidates to inhibit "in vitro" damage to rat hepatocytes. This hepatoprotective effect found could be associated with the antioxidant properties observed for the products.

Simultaneous determination of vitexin-2"-O-glucoside, vitexin-2"-O-rhamnoside, rutin, and hyperoside in the extract of hawthorn (Crataegus pinnatifida Bge.) leaves by RP-HPLC with ultraviolet photodiode array detection.

PubMed

Cheng, Shan; Qiu, Feng; Huang, Jia; He, Junqi

2007-03-01

RP-HPLC with UV photodiode array detection (UV-DAD) was developed and validated for the simultaneous determination of vitexin-2"-O-glucoside, vitexin-2"-O-rhamnoside, rutin, and hyperoside in the extract of hawthorn (Crataegus pinnatifida Bge.) leaves. The analytes of interest were separated on a Diamonsil C18 column (250 x 4.6 mm id, 5 microm) with the mobile phase consisting of THF/ACN/methanol/ 0.05% phosphoric acid solution (pH 5.0) (18:1:1:80 v/vl/v). The flow rate was set at 1.0 mL/min and the eluent was detected at 340 nm for the four flavonoids. The method was linear over the studied range of 1.00-100 microg/mL for the four analytes of interest with the correlation coefficient for each analyte greater than 0.999. The LOD and LOQwere 0.03 and 0.10 microg/mL, 0.03 and 0.10 microg/mL, 0.05 and 0.15 pg/mL, 0.10 and 0.30 microg/mL for vitexin-2"-O-glucoside, vitexin-2"-0-rhamnoside, rutin, and hyperoside, respectively. The optimized method was successfully applied to the analysis of four important flavonoids in the extract of hawthorn leaves. The total amounts of the four flavonoids were 22.2, 62.3, 4.27, and 8.24 mg/g dry weight for vitexin-2"-O-glucoside, vitexin-2"-O-rhamnoside, rutin, and hyperoside in the extract of hawthorn leaves, respectively.

Quantitative analysis of phenolic compounds in Chinese hawthorn (Crataegus spp.) fruits by high performance liquid chromatography-electrospray ionisation mass spectrometry.

PubMed

Liu, Pengzhan; Kallio, Heikki; Lü, Deguo; Zhou, Chuansheng; Yang, Baoru

2011-08-01

Eleven major phenolic compounds (hyperoside, isoquercitrin, chlorogenic acid, ideain, epicatechin, two procyanidin (PA) dimers, three PA trimers and a PA dimer-hexoside) were quantified in the fruits of 22 cultivars/origins of three species of the Chinese hawthorn (Crataegus spp.) by HPLC-ESI-MS-SIR. Hyperoside (0.1-0.8mg/g dry mass [DM]), isoquercitrin (0.1-0.3mg/g DM), chlorogenic acid (0.2-1.6mg/g DM), epicatechin (0.9-11.7mg/g DM), PA B2 (0.7-12.4mg/g DM), PA dimer II (0.1-1.5mg/g DM), PA trimer I (0.1-2.7mg/g DM), PA trimer II (0.7-6.9mg/g DM), PA trimer III (0.01-1.2mg/g DM) and a PA dimer-hexoside (trace-1.1mg/g DM) were detected in all the samples. Ideain (0.0-0.7mg/g DM) was found in all the samples except Crataegus scabrifolia. Significant correlations between the contents of individual PA aglycons were observed (r>0.9, P<0.01). A strong correlation between flavonols was also shown (r=0.71, P<0.01). Fruits of Crataegus pinnatifida var. major had higher contents of PAs but lower contents of flavonols compared with Crataegus brettschneideri. The fruits of C. scabrifolia contained the highest level of PA dimer-hexoside, which was present in trace amounts in the fruits of C. pinnatifida. Copyright © 2011 Elsevier Ltd. All rights reserved.

Surface Flooding from Hurricane Harvey Shown in New SMAP Imagery

NASA Image and Video Library

2017-08-30

A new series of images generated with data from NASA's Soil Moisture Active Passive (SMAP) satellite illustrate the surface flooding caused by Hurricane Harvey from before its initial landfall through August 27, 2017. The SMAP observations detect the proportion of the ground covered by surface water within the satellite's field of view. The sequence of images depicts successive satellite orbital swath observations showing the surface water conditions on August 22, before Harvey's landfall (left), and then on Aug. 27, two days after landfall (middle). The resulting increase in surface flooding from record rainfall over the three-day period, shown at right, depicts regionally heavy flooding around the Houston metropolitan area. The hardest hit areas (blue and purple shades) cover more than 23,000 square miles (about 59,600 square kilometers) and indicate a more than 1,000-fold increase in surface water cover from rainfall-driven flooding. SMAP's low-frequency (L-band) microwave radiometer features enhanced capabilities for detecting surface water changes in nearly all weather conditions and under low-to-moderate vegetation cover. The satellite provides global coverage with one to three-day repeat sampling, which is well suited for monitoring dynamic inland waters around the world. https://photojournal.jpl.nasa.gov/catalog/PIA21930

Hurricane Harvey, Houston's Petrochemical Industry, and US Chemical Safety Policy: Impacts to Environmental Justice Communities

NASA Astrophysics Data System (ADS)

Goldman, G. T.; Johnson, C.; Gutierrez, A.; Declet-Barreto, J.; Berman, E.; Bergman, A.

2017-12-01

When Hurricane Harvey made landfall outside Houston, Texas, the storm's wind speeds and unprecedented precipitation caused significant damage to the region's petrochemical infrastructure. Most notably, the company Arkema's Crosby facility suffered a power failure that led to explosions and incineration of six of its peroxide tanks. Chemicals released into the air from the explosions sent 15 emergency responders to the hospital with severe respiratory conditions and led to the evacuation of hundreds of surrounding households. Other petrochemical facilities faced other damages that resulted in unsafe and acute chemical releases into the air and water. What impacts did such chemical disasters have on the surrounding communities and emergency responders during Harvey's aftermath? What steps might companies have taken to prevent such chemical releases? And what chemical safety policies might have ensured that such disaster risks were mitigated? In this talk we will report on a survey of the extent of damage to Houston's oil and gas infrastructure and related chemical releases and discuss the role of federal chemical safety policy in preventing and mitigating the potential for such risks for future storms and other extreme weather and climate events. We will also discuss how these chemical disasters created acute toxics exposures on environmental justice communities already overburdened with chronic exposures from the petrochemical industry.

Building Change Detection from Harvey using Unmanned Aerial System (UAS)

NASA Astrophysics Data System (ADS)

Chang, A.; Yeom, J.; Jung, J.; Choi, I.

2017-12-01

Unmanned Aerial System (UAS) is getting to be the most important technique in recent days since the fine spatial and high temporal resolution data previously unobtainable from traditional remote sensing platforms. Advanced UAS data can provide a great opportunity for disaster monitoring. Especially, building change detection is the one of the most important topics for damage assessment and recovery from disasters. This study is proposing a method to monitor building change with UAS data for Holiday Beach in Texas, where was directly hit by Harvey on 25 August 2017. This study adopted 3D change detection to monitor building damage and recovery levels with building height as well as natural color information. We used a rotorcraft UAS to collect RGB data twice on 9 September and 18 October 2017 after the hurricane. The UAS data was processed using Agisoft Photoscan Pro Software to generate super high resolution dataset including orthomosaic, DSM (Digital Surface Model), and 3D point cloud. We compared the processed dataset with an airborne image considerable as before-hurricane data, which was acquired on January 2016. Building damage and recovery levels were determined by height and color change. The result will show that UAS data is useful to assess building damage and recovery for affected area by the natural disaster such as Harvey.

Hydrology and hydraulics of Cypress Creek watershed, Texas during Hurricane Harvey and Impact of Potential Mitigation Measures.

NASA Astrophysics Data System (ADS)

El Hassan, A.; Fares, A.; Risch, E.

2017-12-01

Rain resulting from Hurricane Harvey stated to spread into Harris County late in August 25 and continued until August 31 2017. This high intensity rainfall caused catastrophic flooding across the Greater Houston Area and south Texas. The objectives of this study are to use the USACE Gridded Surface Subsurface Hydrologic Analysis model (GSSHA) to: i) simulate the hydrology and hydraulics of Cypress Creek watershed and quantify the impact of hurricane Harvey on it; and ii) test potential mitigation measures, e.g., construction of a third surface reservoir on the flooding and hydrology of this watershed. Cypress Creek watershed area is 733 km2. Simulations were conducted using precipitation from two sources a) the Multisensory Precipitation Estimator radar products (MPE) and Multi-Radar Multi-Sensor (MRMS) system. Streamflow was downloaded from the USGS gauge at the outlet of the watershed. The models performance using both precipitation data was very reasonable. The construction of an 8 m high embankment at the south central part of the watershed resulted in over 22% reduction of the peak flow of the stream and also reduction of the depth of inundation across the east part of the watershed. These and other mitigation scenarios will be further discussed in details during the presentation.

Harvey Guthrey | NREL

Science.gov Websites

advanced electron-microscopy-based characterization techniques to the study of photovoltaics and energy -storage materials. Research Interests Combining structural and chemical characterization techniques to

Steve P. Harvey | NREL

Science.gov Websites

photoemission measurements to better understand materials fundamentals and degradation in semiconductor, organic , investigating root-cause mechanisms of degradation in photovoltaic modules, investigating organic-inorganic

Extreme Wind, Rain, Storm Surge, and Flooding: Why Hurricane Impacts are Difficult to Forecast?

NASA Astrophysics Data System (ADS)

Chen, S. S.

2017-12-01

The 2017 hurricane season is estimated as one of the costliest in the U.S. history. The damage and devastation caused by Hurricane Harvey in Houston, Irma in Florida, and Maria in Puerto Rico are distinctly different in nature. The complexity of hurricane impacts from extreme wind, rain, storm surge, and flooding presents a major challenge in hurricane forecasting. A detailed comparison of the storm impacts from Harvey, Irma, and Maria will be presented using observations and state-of-the-art new generation coupled atmosphere-wave-ocean hurricane forecast model. The author will also provide an overview on what we can expect in terms of advancement in science and technology that can help improve hurricane impact forecast in the near future.

Measuring the impostor phenomenon: a comparison of Clance's IP Scale and Harvey's I-P Scale.

PubMed

Holmes, S W; Kertay, L; Adamson, L B; Holland, C L; Clance, P R

1993-02-01

Many of the discrepancies reported to date in empirical investigations of the impostor phenomenon (IP) may be due in part to (a) the use of different methods for identifying individuals suffering from this syndrome (impostors), (b) the common use of a median split procedure to classify subjects and (c) the fact that subjects in many studies were drawn from impostor-prone samples. In this study, we compared the scores of independently identified impostors and nonimpostors on two instruments designed to measure the IP: Harvey's I-P Scale and Clance's IP Scale. The results suggest that Clance's scale may be the more sensitive and reliable instrument. Cutoff score suggestions for both instruments are offered.

Assessing the present and future probability of Hurricane Harvey's rainfall.

PubMed

Emanuel, Kerry

2017-11-28

We estimate, for current and future climates, the annual probability of areally averaged hurricane rain of Hurricane Harvey's magnitude by downscaling large numbers of tropical cyclones from three climate reanalyses and six climate models. For the state of Texas, we estimate that the annual probability of 500 mm of area-integrated rainfall was about 1% in the period 1981-2000 and will increase to 18% over the period 2081-2100 under Intergovernmental Panel on Climate Change (IPCC) AR5 representative concentration pathway 8.5. If the frequency of such event is increasingly linearly between these two periods, then in 2017 the annual probability would be 6%, a sixfold increase since the late 20th century. Copyright © 2017 the Author(s). Published by PNAS.

Integrated Field Testing of Fuel Cells and Micro-Turbines

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jerome R. Temchin; Stephen J. Steffel

A technical and economic evaluation of the prospects for the deployment of distributed generation on Long Beach Island, New Jersey concluded that properly sited DG would defer upgrading of the electric power grid for 10 years. This included the deployment of fuel cells or microturbines as well as reciprocating engines. The implementation phase of this project focused on the installation of a 120 kW CHP microturbine system at the Harvey Cedars Bible Conference in Harvey Cedars, NJ. A 1.1 MW generator powered by a gas-fired reciprocating engine for additional grid support was also installed at a local substation. This reportmore » contains installation and operation issues as well as the utility perspective on DG deployment.« less

A brief history of the discovery of the circulation of blood in the human body.

PubMed

Azizi, Mohammad-Hossein; Nayernouri, Touraj; Azizi, Farzaneh

2008-05-01

The present article describes briefly the development of the theories regarding the circulation of blood in humans, from the time of Galen (second century C.E.) to the work of William Harvey (17th century C.E.).We shall summarize the views of Galen together with those of two prominent Iranian physicians of the Middle Ages (Razi and Ahwazi known in the West as Rhazes and Haly Abbas respectively) as well as that of Ibn-Nafis from Damascus (the discoverer of the pulmonary circulation) and the Spanish physician and cleric Michael Servetus and finally the definitive work of William Harvey, the English physician who described the mechanism of both the systemic and pulmonary circulation of blood in the human body.

Antidepressant Withdrawal

MedlinePlus

... www.uptodate.com/home. Accessed Dec. 11, 2015. Definition of addiction. American Society of Addiction Medicine. http://www.asam.org/for-the-public/definition-of-addiction. Accessed Dec. 11, 2015. Harvey BH, ...

Simulation of groundwater conditions and streamflow depletion to evaluate water availability in a Freeport, Maine, watershed

USGS Publications Warehouse

Nielsen, Martha G.; Locke, Daniel B.

2012-01-01

In order to evaluate water availability in the State of Maine, the U.S. Geological Survey (USGS) and the Maine Geological Survey began a cooperative investigation to provide the first rigorous evaluation of watersheds deemed "at risk" because of the combination of instream flow requirements and proportionally large water withdrawals. The study area for this investigation includes the Harvey and Merrill Brook watersheds and the Freeport aquifer in the towns of Freeport, Pownal, and Yarmouth, Maine. A numerical groundwater- flow model was used to evaluate groundwater withdrawals, groundwater-surface-water interactions, and the effect of water-management practices on streamflow. The water budget illustrates the effect that groundwater withdrawals have on streamflow and the movement of water within the system. Streamflow measurements were made following standard USGS techniques, from May through September 2009 at one site in the Merrill Brook watershed and four sites in the Harvey Brook watershed. A record-extension technique was applied to estimate long-term monthly streamflows at each of the five sites. The conceptual model of the groundwater system consists of a deep, confined aquifer (the Freeport aquifer) in a buried valley that trends through the middle of the study area, covered by a discontinuous confining unit, and topped by a thin upper saturated zone that is a mixture of sandy units, till, and weathered clay. Harvey and Merrill Brooks flow southward through the study area, and receive groundwater discharge from the upper saturated zone and from the deep aquifer through previously unknown discontinuities in the confining unit. The Freeport aquifer gets most of its recharge from local seepage around the edges of the confining unit, the remainder is received as inflow from the north within the buried valley. Groundwater withdrawals from the Freeport aquifer in the study area were obtained from the local water utility and estimated for other categories. Overall, the public-supply withdrawals (105.5 million gallons per year (Mgal/yr)) were much greater than those for any other category, being almost 7 times greater than all domestic well withdrawals (15.3 Mgal/yr). Industrial withdrawals in the study area (2.0 Mgal/yr) are mostly by a company that withdraws from an aquifer at the edge of the Merrill Brook watershed. Commercial withdrawals are very small (1.0 Mgal/yr), and no irrigation or other agricultural withdrawals were identified in this study area. A three-dimensional, steady-state groundwater-flow model was developed to evaluate stream-aquifer interactions and streamflow depletion from pumping, to help refine the conceptual model, and to predict changes in streamflow resulting from changes in pumping and recharge. Groundwater levels and flow in the Freeport aquifer study area were simulated with the three-dimensional, finite-difference groundwater-flow modeling code, MODFLOW-2005. Study area hydrology was simulated with a 3-layer model, under steady-state conditions. The groundwater model was used to evaluate changes that could occur in the water budgets of three parts of the local hydrologic system (the Harvey Brook watershed, the Merrill Brook watershed, and the buried aquifer from which pumping occurs) under several different climatic and pumping scenarios. The scenarios were (1) no pumping well withdrawals; (2) current (2009) pumping, but simulated drought conditions (20-percent reduction in recharge); (3) current (2009) recharge, but a 50-percent increase in pumping well withdrawals for public supply; and (4) drought conditions and increased pumping combined. In simulated drought situations, the overall recharge to the buried valley is about 15 percent less and the total amount of streamflow in the model area is reduced by about 19 percent. Without pumping, infiltration to the buried valley aquifer around the confining unit decreased by a small amount (0.05 million gallons per day (Mgal/d)), and discharge to the streams increased by about 8 percent (0.3 Mgal/d). A 50-percent increase in pumping resulted in a simulated decrease in streamflow discharge of about 4 percent (0.14 Mgal/d). Streamflow depletion in Harvey Brook was evaluated by use of the numerical groundwater-flow model and an analytical model. The analytical model estimated negligible depletion from Harvey Brook under current (2009) pumping conditions, whereas the numerical model estimated that flow to Harvey Brook decreased 0.38 cubic feet per second (ft3/s) because of the pumping well withdrawals. A sensitivity analysis of the analytical model method showed that conducting a cursory evaluation using an analytical model of streamflow depletion using available information may result in a very wide range in results, depending on how well the hydraulic conductivity variables and aquifer geometry of the system are known, and how well the aquifer fits the assumptions of the model. Using the analytical model to evaluate the streamflow depletion with an incomplete understanding of the hydrologic system gave results that seem unlikely to reflect actual streamflow depletion in the Freeport aquifer study area. In contrast, the groundwater-flow model was a more robust method of evaluating the amount of streamflow depletion that results from withdrawals in the Freeport aquifer, and could be used to evaluate streamflow depletion in both streams. Simulations of streamflow without pumping for each measurement site were compared to the calibratedmodel streamflow (with pumping), the difference in the total being streamflow depletion. Simulations without pumping resulted in a simulated increase in the steady-state flow rate of 0.38 ft3/s in Harvey Brook and 0.01 ft3/s in Merrill Brook. This translates into a streamflow-depletion amount equal to about 8.5 percent of the steady-state base flow in Harvey Brook, and an unmeasurable amount of depletion in Merrill Brook. If pumping was increased by 50 percent and recharge reduced by 20 percent, the amount of streamflow depletion in Harvey Brook could reach 1.41 ft3/s.

Early reactions to Harvey's circulation theory: the impact on medicine.

PubMed

Lubitz, Steven A

2004-09-01

In early 17th century Europe, scientific concepts were still based largely on ancient philosophical and theological explanations. During this same era, however, experimentation began to take hold as a legitimate component of scientific investigation. In 1628, the English physician William Harvey announced a revolutionary theory stating that blood circulates repeatedly throughout the body. He relied on experimentation, comparative anatomy and calculation to arrive at his conclusions. His theory contrasted sharply with the accepted beliefs of the time, which were based on the 1400-year-old teachings of Galen and denied the presence of circulation. As with many new ideas, Harvey's circulation theory was received with a great deal of controversy among his colleagues. An examination of their motives reveals that many proponents agreed with his theory largely because of the logic of his argument and his use of experimentation and quantitative methods. However, some proponents agreed for religious, mystical and philosophical reasons, while some were convinced only because of the change in public opinion with time. Many opposed the circulation theory because of their rigid commitment to ancient doctrines, the questionable utility of experimentation, the lack of proof that capillaries exist, and a failure to recognize the clinical applications of his theory. Other opponents were motivated by personal resentments and professional "territorialism." Beyond the immediate issues and arguments, however, the controversy is important because it helped establish use of the scientific method.

Back-barrier Topographic Control on the Morphology of Hurricane Harvey Washover Deposits

NASA Astrophysics Data System (ADS)

Wilson, K.; Swartz, J. M.; Mohrig, D. C.

2017-12-01

Hurricane Harvey rapidly intensified to a category 4 storm before making landfall on the Texas coast on August 25, 2017. Elevated water levels from storm surge and high waves produced widespread erosion, characterized by a landward shift of the shoreline and dune position in excess of 10 m, along greater than 200 km of the Texas coast. In areas of low relief along the pre-storm berm crest, washover fans were deposited. Using post-Harvey observations at Matagorda Peninsula and Sargent Beach, Texas, we investigate a variety of washover fan morphologies which ranged from thick (30 - 50 cm) fans with sharp landward terminations to thin (<10 cm) deposits with diffuse landward terminations. We suggest that the pre-storm back-barrier topography sets the thickness and length of washovers deposited landward of the pre-storm berm. We found subtle differences in back-barrier elevation that lead to distinct deposit styles: small local basins promote sediment accumulation, forming thick fan-shaped deposits while relatively flat topography results in thin, digitate washover morphology. Landward termination of these digitate forms are typically marked by small dams of detrital woody debris. The variability and relative prevalence between the observed morphologies have implications for the resilience of barrier islands over time. Localized, thick fan deposits could provide a more suitable foundation for reestablishment of vegetation and berm elevation, resulting in a more resilient shoreline.

New NASA Maps Show Flooding Changes In Aftermath of Hurricane Harvey

NASA Image and Video Library

2017-09-13

Data from NASA's Soil Moisture Active Passive (SMAP) satellite have been used to create new surface flooding maps of Southeast Texas and the Tennessee Valley following Hurricane Harvey. The SMAP observations detect the proportional cover of surface water within the satellite sensor's field of view. This sequence of images shows changes in the extent of surface flooding from successive five-day SMAP observation composite images. Widespread flooding can be seen in the Houston metropolitan area on Aug. 27 following record rainfall from the Category 4 hurricane, which made landfall on Aug. 25th, 2017 (left image). Flood waters around Houston had substantially receded by Aug. 31 (middle image), while flooding had increased across Louisiana, eastern Arkansas, and western Tennessee as then Tropical Storm Harvey passed over the area. The far right image shows the change in flooded area between Aug. 27 and Aug. 31, with regions showing the most flooding recession depicted in yellow and orange shades and those where flooding had increased depicted in blue shades. The SMAP satellite has a low-frequency (L-band) microwave radiometer with enhanced capabilities for detecting surface water changes in nearly all weather conditions and under low-to-moderate vegetation cover. SMAP provides global coverage with one-to-three-day repeat sampling that is well suited for global monitoring of inland surface water cover dynamics. https://photojournal.jpl.nasa.gov/catalog/PIA21951

Flood Inundation Mapping and Emergency Operations during Hurricane Harvey

NASA Astrophysics Data System (ADS)

Fang, N. Z.; Cotter, J.; Gao, S.; Bedient, P. B.; Yung, A.; Penland, C.

2017-12-01

Hurricane Harvey struck the Gulf Coast as Category 4 on August 25, 2017 with devastating and life-threatening floods in Texas. Harris County received up to 49 inches of rainfall over a 5-day period and experienced flooding level and impacts beyond any previous storm in Houston's history. The depth-duration-frequency analysis reveals that the areal average rainfall for Brays Bayou surpasses the 500-year rainfall in both 24 and 48 hours. To cope with this unprecedented event, the researchers at the University of Texas at Arlington and Rice University worked closely with the U.S. Army Corps of Engineers (USACE), the National Weather Service (NWS), the Texas Division of Emergency Management (TDEM), Walter P. Moore and Associates, Inc. and Halff Associates, to conduct a series of meteorological, hydrologic and hydraulic analyses to delineate flood inundation maps. Up to eight major watersheds in Harris County were delineated based the available QPE data from WGRFC. The inundation map over Brays Bayou with their impacts from Hurricane Harvey was delineated in comparison with those of 100-, 500-year, and Probable Maximum Precipitation (PMP) design storms. This presentation will provide insights for both engineers and planners to re-evaluate the existing flood infrastructure and policy, which will help build Houston stronger for future extreme storms. The collaborative effort among the federal, academic, and private entities clearly demonstrates an effective approach for flood inundation mapping initiatives for the nation.

6. Historic American Buildings Survey, Louis I. Schwartz, Photographer CONSTRUCTION ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Historic American Buildings Survey, Louis I. Schwartz, Photographer CONSTRUCTION DETAIL, SECOND FLOOR ROOM. - Harvey-Lining House & Pharmacy, Broad & Kings Streets, Charleston, Charleston County, SC

Evaluation of Hypolipidemic and Antioxidant Effects in Phenolrich Fraction of Crataegus pinnatifida Fruit in Hyperlipidemia Rats and Identification of Chemical Composition by Ultra-performance Liquid Chromatography Coupled with Quadropole Time-of-flight Mass Spectrometry

PubMed Central

Shao, Feng; Gu, Lifei; Chen, Huijuan; Liu, Ronghua; Huang, Huilian; Chen, Lanying; Yang, Ming

2017-01-01

Background: Hawthorn (Crataegus pinnatifida) fruit has enjoyed a great popularity as a pleasant-tasting food associated with hypolipidemic and antioxidant effects. Objective: Our aim was to screen the effective fraction of hawthorn fruit in the treatment of hyperlipidemia rats. Materials and Methods: In this study, ethanol extract of hawthorn fruit (Fr.1) and four fractionated extracts (Fr.2, Fr.3, Fr.4, and Fr.5) were compared to total phenol content evaluated using Folin–Ciocalteu method, and hypolipidemic and antioxidant effects were assessed in hyperlipidemic rats. Results: Total phenol content of Fr.4 was higher than other fractions by at least 2 fold. Furthermore, this fraction possessed the strongest hypolipidemic and antioxidant effects in hyperlipidemic rats. On this basis, 15 phenolic compounds and four organic acids in Fr.4 were positively or tentatively identified using ultra-performance liquid chromatography coupled with quadropole time-of-flight mass spectrometry. In addition, 5-O-caffeoyl quinic acid butyl ester was first reported in hawthorn fruit. Conclusion: Phenol-rich fraction in hawthorn fruit exhibited satisfactory hypolipidemic and antioxidant effects, and this could be exploited for further promotion of functional foods. SUMMARY Phenol-rich fraction in hawthorn fruit possesses most potent hypolipidemic and antioxidant effects in hyperlidemia rats. Abbreviations used: UPLC-Q-TOF-MS/MS: Ultra performance liquid chromatography coupled with quadropole time-of-flight mass spectrometry; TC: Total cholesterol; TG: Triglyceride; LDL-C: Low-density lipoprotein-cholesterol; HDL-C: High-density lipoprotein-cholesterol; GSH-Px: Glutathione peroxidase; SOD: Superoxide dismutase; MDA: Malondialdehyde; CAT: Catalase; NO: Nitric oxide; NOS: Nitric oxide synthase; ROS: Reactive oxygen species; •OOH: Superoxide anions, •OH: Hydroxyl radicals. PMID:29200740

Comparation of Hypolipidemic and Antioxidant Effects of Aqueous and Ethanol Extracts of Crataegus pinnatifida Fruit in High-Fat Emulsion-Induced Hyperlipidemia Rats

PubMed Central

Shao, Feng; Gu, Lifei; Chen, Huijuan; Liu, Ronghua; Huang, Huilian; Ren, Gang

2016-01-01

Background: Hawthorn (Crataegus pinnatifida) is a Chinese medicinal plant traditionally used in the treatment of hyperlipidemia. Recently, studies indicated free radical scavenging was one of the major pathways to alleviate hyperlipidemia. Moreover, hawthorn fruit is a rich source of phenols, which quench free radical and attenuate hyperlipidemia. However, the phenols vary with processing methods, especially solvent type. Objective: Our aim was to compare hypolipidemic and antioxidant effects of aqueous and ethanol extracts of hawthorn fruit in hyperlipidemia rats. Materials and Methods: After a 4-week treatment of high-fat emulsion, lipid profile levels and antioxidant levels of two extracts were determined using commercial analysis. Total phenols content in the extract of hawthorn fruit was determined colorimetrically by the Folin–Ciocalteu method. Results: Both ethanol and aqueous extracts of hawthorn fruit possessed hypolipidemic and antioxidant activities. Simultaneously, stronger activities were observed in ethanol extract. Besides, total phenols content in ethanol extract from the same quality of hawthorn fruit was 3.9 times more than that in aqueous extract. Conclusion: The obvious difference of hypolipidemic and antioxidant effects between ethanol extract and aqueous extract of hawthorn fruit was probably due to the presence of total phenols content, under the influence of extraction solvent. SUMMARY Ethanol extract of hawthorn fruit exhibited more favorable hypolipidemic and antioxidant effects than aqueous extract. The higher effects could be due to the higher content of total phenols that varies with extraction solvent. Abbreviations used: TC: Total cholesterol, TG: Triglyceride, LDL-C: Low-density lipoprotein cholesterol, HDL-C: High-density lipoprotein cholesterol, GSH-Px: Glutathione peroxidase, SOD: Superoxide dismutase, MDA: Malondialdehyde, CAT: Catalase, NO: Nitric oxide, NOS: Nitric oxide synthase, SR-BI: Scavenger receptor Class B Type I PMID:27019563

Evaluation of Hypolipidemic and Antioxidant Effects in Phenolrich Fraction of Crataegus pinnatifida Fruit in Hyperlipidemia Rats and Identification of Chemical Composition by Ultra-performance Liquid Chromatography Coupled with Quadropole Time-of-flight Mass Spectrometry.

PubMed

Shao, Feng; Gu, Lifei; Chen, Huijuan; Liu, Ronghua; Huang, Huilian; Chen, Lanying; Yang, Ming

2017-01-01

Hawthorn ( Crataegus pinnatifida ) fruit has enjoyed a great popularity as a pleasant-tasting food associated with hypolipidemic and antioxidant effects. Our aim was to screen the effective fraction of hawthorn fruit in the treatment of hyperlipidemia rats. Materials and Methods: In this study, ethanol extract of hawthorn fruit (Fr.1) and four fractionated extracts (Fr.2, Fr.3, Fr.4, and Fr.5) were compared to total phenol content evaluated using Folin-Ciocalteu method, and hypolipidemic and antioxidant effects were assessed in hyperlipidemic rats. Total phenol content of Fr.4 was higher than other fractions by at least 2 fold. Furthermore, this fraction possessed the strongest hypolipidemic and antioxidant effects in hyperlipidemic rats. On this basis, 15 phenolic compounds and four organic acids in Fr.4 were positively or tentatively identified using ultra-performance liquid chromatography coupled with quadropole time-of-flight mass spectrometry. In addition, 5-O-caffeoyl quinic acid butyl ester was first reported in hawthorn fruit. Phenol-rich fraction in hawthorn fruit exhibited satisfactory hypolipidemic and antioxidant effects, and this could be exploited for further promotion of functional foods. Phenol-rich fraction in hawthorn fruit possesses most potent hypolipidemic and antioxidant effects in hyperlidemia rats. Abbreviations used: UPLC-Q-TOF-MS/MS: Ultra performance liquid chromatography coupled with quadropole time-of-flight mass spectrometry; TC: Total cholesterol; TG: Triglyceride; LDL-C: Low-density lipoprotein-cholesterol; HDL-C: High-density lipoprotein-cholesterol; GSH-Px: Glutathione peroxidase; SOD: Superoxide dismutase; MDA: Malondialdehyde; CAT: Catalase; NO: Nitric oxide; NOS: Nitric oxide synthase; ROS: Reactive oxygen species; •OOH: Superoxide anions, •OH: Hydroxyl radicals.

Comparation of Hypolipidemic and Antioxidant Effects of Aqueous and Ethanol Extracts of Crataegus pinnatifida Fruit in High-Fat Emulsion-Induced Hyperlipidemia Rats.

PubMed

Shao, Feng; Gu, Lifei; Chen, Huijuan; Liu, Ronghua; Huang, Huilian; Ren, Gang

2016-01-01

Hawthorn (Crataegus pinnatifida) is a Chinese medicinal plant traditionally used in the treatment of hyperlipidemia. Recently, studies indicated free radical scavenging was one of the major pathways to alleviate hyperlipidemia. Moreover, hawthorn fruit is a rich source of phenols, which quench free radical and attenuate hyperlipidemia. However, the phenols vary with processing methods, especially solvent type. Our aim was to compare hypolipidemic and antioxidant effects of aqueous and ethanol extracts of hawthorn fruit in hyperlipidemia rats. After a 4-week treatment of high-fat emulsion, lipid profile levels and antioxidant levels of two extracts were determined using commercial analysis. Total phenols content in the extract of hawthorn fruit was determined colorimetrically by the Folin-Ciocalteu method. Both ethanol and aqueous extracts of hawthorn fruit possessed hypolipidemic and antioxidant activities. Simultaneously, stronger activities were observed in ethanol extract. Besides, total phenols content in ethanol extract from the same quality of hawthorn fruit was 3.9 times more than that in aqueous extract. The obvious difference of hypolipidemic and antioxidant effects between ethanol extract and aqueous extract of hawthorn fruit was probably due to the presence of total phenols content, under the influence of extraction solvent. Ethanol extract of hawthorn fruit exhibited more favorable hypolipidemic and antioxidant effects than aqueous extract. The higher effects could be due to the higher content of total phenols that varies with extraction solvent. Abbreviations used: TC: Total cholesterol, TG: Triglyceride, LDL-C: Low-density lipoprotein cholesterol, HDL-C: High-density lipoprotein cholesterol, GSH-Px: Glutathione peroxidase, SOD: Superoxide dismutase, MDA: Malondialdehyde, CAT: Catalase, NO: Nitric oxide, NOS: Nitric oxide synthase, SR-BI: Scavenger receptor Class B Type I.

Synergetic effect and structure-activity relationship of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors from Crataegus pinnatifida Bge.

PubMed

Ye, Xiao-Li; Huang, Wen-Wen; Chen, Zhu; Li, Xue-Gang; Li, Ping; Lan, Ping; Wang, Liang; Gao, Ying; Zhao, Zhong-Qi; Chen, Xin

2010-03-10

The 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) inhibitors from hawthorn fruit ( Crataegus pinnatifida Bge.) were isolated and evaluated for their antihyperlipidemic effect induced by high-fat diet in mice. After being further purified with silica and polyamide column chromatography from the fractions (fractions A, F, H, and G) with a high inhibitory rate (IR) to HMGR, 24 chromatographic fractions were obtained, including 8 active fractions with a high IR to HMGR. However, the total inhibitory activity of 24 fractions was decreased by about 70%. From eight active fractions, four compounds were obtained by recrystallization and identified as quercetin (a), hyperoside (b), rutin (c), and chlorogenic acid (d), the contents of which in hawthorn EtOH extract were 0.16, 0.32, 1.45, and 0.95%, respectively. The IR values of compounds a-d to HMGR were 6.28, 9.64, 23.53, and 10.56% at the corresponding concentrations of 0.16, 0.32, 1.45, and 0.95 mg/mL, respectively. It was discovered that the IR of a mixture (2.85 mg/mL) matching the original percentage of compounds a-d in hawthorn EtOH extract was up to 79.5%, much higher than that of the single compound and the total IR of these four compounds (50.01%). The in vivo results also revealed that the mixture had a more significant lipid-lowering efficacy than the monomers. Structure-activity relationship revealed the inhibitory activity and lowering-lipid ability of compounds a-c decreased with increasing glycoside numbers. It was concluded that there were synergetic effects on inhibiting HMGR and lowering lipid among compounds a-d, and the weak hydrophilic ability benefits the inhibition to HMGR and lowering-lipid efficacy.

Recent Atlantic Hurricanes, Pacific Super Typhoons, and Tropical Storm Awareness in Underdeveloped Island and Coastal Regions

NASA Astrophysics Data System (ADS)

Plondke, D. L.

2017-12-01

Hurricane Harvey was the first major hurricane to make landfall in the continental U.S. in 12 years. The next tropical storm in the 2017 Atlantic Hurricane Season was Hurricane Irma, a category 5 storm and the strongest storm to strike the U.S. mainland since Hurricane Wilma in 2005. These two storms were the third and fourth in a sequence of 10 consecutive storms to reach hurricane status in this season that ranks at least seventh among the most active seasons as measured by the Accumulate Cyclone Energy (ACE) index. Assessment of damage from Harvey may prove it to be the costliest storm in U.S. history, approaching $190 billion. Irma was the first category 5 hurricane to hit the Leeward Islands, devastating island environments including Puerto Rico, the Virgin Islands, Barbuda, Saint Barthelemy, and Anguilla with sustained winds reaching at times 185 mph. Together with the two super typhoons of the 2017 Pacific season, Noru and Lan, the two Atlantic hurricanes rank among the strongest, longest-lasting tropical cyclones on record. How many more billions of dollars will be expended in recovery and reconstruction efforts following future mega-disasters comparable to those of Hurricanes Harvey and Irma? Particularly on Caribbean and tropical Pacific islands with specialized and underdeveloped economies, aging and substandard infrastructure often cannot even partially mitigate against the impacts of major hurricanes. The most frequently used measurements of storm impact are insufficient to assess the economic impact. Analysis of the storm tracks and periods of greatest storm intensity of Hurricanes Harvey and Irma, and Super Typhoons Lan and Noru, in spatial relationship with island and coastal administrative regions, shows that rainfall totals, flooded area estimates, and property/infrastructure damage dollar estimates are all quantitative indicators of storm impact, but do not measure the costs that result from lack of storm preparedness and education of residents about the urgency of climate change mitigation. Lacking in most of the island and coastal environments where major storms occur and are likely to occur more frequently in the future are educational opportunities and public dissemination of information about climate change forecasts, storm impact mitigation, and emergency preparedness.

Hurricane Harvey & Houston: Hell or High Water

NASA Astrophysics Data System (ADS)

Bedient, P. B.

2017-12-01

Harvey was the largest rainfall and most damaging flood event in US history. By all measures the widespread impact was a devastating blow to all of Houston and surrounding areas. It dropped between 36 and 52 inches along the Texas coast over 5 days, exceeding all previous rainfall records, with up to 20 inches in a day. However, two earlier events from 2015 and 2016 also brought widespread flooding to many parts of Houston, especially concentrated in a few watersheds. Most bayous during Harvey were over bank by as much as 10 ft, and flooded an estimated 136000 homes in Harris county alone, greatly exceeding the massive TS Allison impact of 2001. While the area deals with a significant recovery effort, there is a massive call to action on the part of politicians, governmental agencies, and those affected by this event. There is need for a better statistical basis of rainfalls and floodplain mapping in Houston. Development patterns and density have come into question, as homes have been either built in 100 yr floodplains or taken into those floodplains over time. Estimates say > 47 % of homes flooded in TS Allison were outside the floodplain. Many homes were built behind Addicks/Barker reservoirs that protect downtown, many with no knowledge that they were in harms way (over 8000 were flooded there alone), and flooded as water reached record setting levels. New technologies have allowed the measurement and prediction of floods to make great strides since the mid 1990s, (Radar, LIDAR, GIS, hydrologic models, floodplain updates) and the Houston area has benefited from these efforts. While the plan going forward is daunting, there are a number of positive steps that are occurring and should lead to more resiliency. There needs to be policy changes on storage and detention requirements, green space & infrastructure improvements, and perhaps a third regional reservoir above Addicks. Also there is a renewed interest in flood warning systems to better inform the public about risk within specific watersheds. There is still a great deal of suffering out there after Harvey, but the three big floods we have just seen should cause a change in the way Houston addresses floodplains and develops into the future.

Medium range forecasting of Hurricane Harvey flash flooding using ECMWF and social vulnerability data

NASA Astrophysics Data System (ADS)

Pillosu, F. M.; Jurlina, T.; Baugh, C.; Tsonevsky, I.; Hewson, T.; Prates, F.; Pappenberger, F.; Prudhomme, C.

2017-12-01

During hurricane Harvey the greater east Texas area was affected by extensive flash flooding. Their localised nature meant they were too small for conventional large scale flood forecasting systems to capture. We are testing the use of two real time forecast products from the European Centre for Medium-range Weather Forecasts (ECMWF) in combination with local vulnerability information to provide flash flood forecasting tools at the medium range (up to 7 days ahead). Meteorological forecasts are the total precipitation extreme forecast index (EFI), a measure of how the ensemble forecast probability distribution differs from the model-climate distribution for the chosen location, time of year and forecast lead time; and the shift of tails (SOT) which complements the EFI by quantifying how extreme an event could potentially be. Both products give the likelihood of flash flood generating precipitation. For hurricane Harvey, 3-day EFI and SOT products for the period 26th - 29th August 2017 were used, generated from the twice daily, 18 km, 51 ensemble member ECMWF Integrated Forecast System. After regridding to 1 km resolution the forecasts were combined with vulnerable area data to produce a flash flood hazard risk area. The vulnerability data were floodplains (EU Joint Research Centre), road networks (Texas Department of Transport) and urban areas (Census Bureau geographic database), together reflecting the susceptibility to flash floods from the landscape. The flash flood hazard risk area forecasts were verified using a traditional approach against observed National Weather Service flash flood reports, a total of 153 reported flash floods have been detected in that period. Forecasts performed best for SOT = 5 (hit ratio = 65%, false alarm ratio = 44%) and EFI = 0.7 (hit ratio = 74%, false alarm ratio = 45%) at 72 h lead time. By including the vulnerable areas data, our verification results improved by 5-15%, demonstrating the value of vulnerability information within natural hazard forecasts. This research shows that flash flooding from hurricane Harvey was predictable up to 4 days ahead and that filtering the forecasts to vulnerable areas provides a more focused guidance to civil protection agencies planning their emergency response.

Did Harvey Learn from Katrina? Initial Observations of the Response to Companion Animals during Hurricane Harvey

PubMed Central

2018-01-01

Simple Summary When Hurricane Harvey struck the Gulf states in 2017, a large-scale rescue effort was launched by officials and citizens to rescue both people and animals. Over a decade since Hurricane Katrina (2005), this study explores whether the reforms to afford better protection to companion animals such as the Pet Emergency and Transportation Standards Act 2006 have made a difference. Key officials from various organizations within the state of Texas were interviewed and it was found that though there has been a cultural shift to better protect animals in a disaster, formal coordination and planning mechanisms need further attention. This study also uncovered the first empirical observation of disaster hoarding where such persons used the disaster to replenish their animal stocks. This study will be of interest to those involved in emergency management and animal welfare. Abstract The aftermath of Hurricane Katrina in 2005 became the genesis of animal emergency management and created significant reforms in the US particularly the passage of the Pets Emergency and Transportation Standards Act in 2006 that required state and local emergency management arrangements to be pet- and service animal-inclusive. More than a decade later Hurricane Harvey struck the Gulf states with all 68 directly related deaths occurring in the state of Texas. In this study, six key officials involved in the response underwent a semi-structured interview to investigate the impact of the PETS Act on preparedness and response. Though the results have limitations due to the low sample size, it was found that the PETS Act and the lessons of Hurricane Katrina had contributed to a positive cultural shift to including pets (companion animals) in emergency response. However, there was a general theme that plans required under the PETS Act were under-developed and many of the animal response lessons from previous emergencies remain unresolved. The study also observed the first empirical case of disaster hoarding which highlights the need for animal law enforcement agencies to be active in emergency response. PMID:29601478

NASA Earth Science Disasters Program Response Activities During Hurricanes Harvey, Irma, and Maria in 2017

NASA Astrophysics Data System (ADS)

Bell, J. R.; Schultz, L. A.; Molthan, A.; Kirschbaum, D.; Roman, M.; Yun, S. H.; Meyer, F. J.; Hogenson, K.; Gens, R.; Goodman, H. M.; Owen, S. E.; Lou, Y.; Amini, R.; Glasscoe, M. T.; Brentzel, K. W.; Stefanov, W. L.; Green, D. S.; Murray, J. J.; Seepersad, J.; Struve, J. C.; Thompson, V.

2017-12-01

The 2017 Atlantic hurricane season included a series of storms that impacted the United States, and the Caribbean breaking a 12-year drought of landfalls in the mainland United States (Harvey and Irma), with additional impacts from the combination of Irma and Maria felt in the Caribbean. These storms caused widespread devastation resulting in a significant need to support federal partners in response to these destructive weather events. The NASA Earth Science Disasters Program provided support to federal partners including the Federal Emergency Management Agency (FEMA) and the National Guard Bureau (NGB) by leveraging remote sensing and other expertise through NASA Centers and partners in academia throughout the country. The NASA Earth Science Disasters Program leveraged NASA mission products from the GPM mission to monitor cyclone intensity, assist with cyclone center tracking, and quantifying precipitation. Multispectral imagery from the NASA-NOAA Suomi-NPP mission and the VIIRS Day-Night Band proved useful for monitoring power outages and recovery. Synthetic Aperture Radar (SAR) data from the Copernicus Sentinel-1 satellites operated by the European Space Agency were used to create flood inundation and damage assessment maps that were useful for damage density mapping. Using additional datasets made available through the USGS Hazards Data Distribution System and the activation of the International Charter: Space and Major Disasters, the NASA Earth Science Disasters Program created additional flood products from optical and radar remote sensing platforms, along with PI-led efforts to derive products from other international partner assets such as the COSMO-SkyMed system. Given the significant flooding impacts from Harvey in the Houston area, NASA provided airborne L-band SAR collections from the UAVSAR system which captured the daily evolution of record flooding, helping to guide response and mitigation decisions for critical infrastructure and public safety. We will provide an overview of the response activities and data products provided by the NASA Earth Science Disasters program, partnerships with federal end-users and the International Charter, and preliminary feedback from end-user partners during response efforts following Hurricanes Harvey, Irma, and Maria..

Center for Science and Technology Policy Research

Science.gov Websites

Expect Surprise: Hurricanes Harvey, Irma, Maria, and Beyond Ten Essentials for Action-Oriented and Second Goldstein Bruce Goldstein Ten Essentials for Action-Oriented and Second Order Energy Transitions

78 FR 16523 - Notice of Public Meeting: Concessions Management Advisory Board

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-15

... previously scheduled for March 20 is cancelled. FOR FURTHER INFORMATION CONTACT: For further information contact Deborah Harvey, Acting Chief, National Park Service, Commercial Services Program, 1201 Eye Street...

77 FR 23277 - Proposed Leasehold Surrender Interest Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-18

... Harvey, Asset Management Branch Chief, 202-513-7150. Before including your address, phone number, email... Management Improvement Act of 1998 (Pub. L. 105-391; 36 CFR part 51), the proposed LSI Guide provides...

Harvey Cushing and some Australian connections: part 1 - early life and work.

PubMed

Roxanas, M G

2010-02-01

Before World War 1 both the United States of America and Australia had rather rudimentary medical systems. Enterprising practitioners in both countries tended to look to continental Europe (especially Germany) and the United Kingdom as places of medical renown. The outbreak of World War 1 changed this but also enabled doctors from both the United States and Australia to work in military hospitals in Europe. The interactions that occurred were important for their professional development and led to some close associations between American and antipodean doctors. Examples of these were the experiences of Harvey Cushing, a burgeoning American neurosurgeon, which he recounted in his diary. His commentary merits close inspection and analysis. An account of some of Cushing's Australian connections post World War 1 is given in Part 2 (in press). Copyright 2009 Elsevier Ltd. All rights reserved.

Prioritizing recovery of urban lifelines in the aftermath of hazards: Transportation in post-Harvey Houston

NASA Astrophysics Data System (ADS)

Warner, M. E.; Bhatia, U.; Sela, L.; Wang, R.; Kodra, E.; Ganguly, A. R.

2017-12-01

A well-designed recovery strategy for lifeline infrastructure networks can lead to faster and more reliable restoration of essential services in the aftermath of natural catastrophes such as hurricanes or earthquakes. Urban and regional lifelines impact one another, while the recovery of urban lifelines in turn impacts regional infrastructural resilience, owing to the interdependence of lifelines across scales. Prior work by our team, often in collaboration, has led to the development of new recovery approaches based on network science and engineering, including centrality measures from network science, information theoretic metrics, and network optimization approaches. We have developed proof-of-concept demonstrations at both regional scales, such as for the Indian Railways Network and the US National Airspace System both subjected to multiple hazards, and to urban settings, such as the post-Hurricane recovery of combined power-subway system-of-systems in Boston and the New York City MTA after Hurricane Sandy. Here we make an attempt to understand how such methods may have been, or continue to be, applicable to the transportation network in Houston post-Harvey, and more broadly, how and to what extent lessons learned in urban and regional resilience may generalize across cases. We make an assessment of the state of the literature, process understanding, simulation models, data science methods, and best practices, necessary to address problems of this nature, with a particular focus on post-Harvey recovery of transportation services in Houston.

As expected Harvey has intensified into a Hurricane

NASA Image and Video Library

2017-08-24

On Aug. 24, the National Hurricane Center noted that Hurricane Harvey was quickly strengthening and is forecast to be a category 3 Hurricane when it approaches the middle Texas coast. In addition, life-threatening storm surge and freshwater flooding expected. On Aug. 24, many warnings and watches were in effect: A Storm Surge Warning is in effect from Port Mansfield to San Luis Pass Texas. A Storm Surge Watch is in effect from south of Port Mansfield Texas to the mouth of the Rio Grande River and from north of San Luis Pass to High Island, Texas. A Hurricane Warning is in effect from Port Mansfield to Matagorda, Texas. A Tropical Storm Warning is in effect from north of Matagorda to High Island, Texas and south of Port Mansfield, Texas to the Mouth of the Rio Grande. A Hurricane Watch is in effect from south of Port Mansfield, Texas to the Mouth of the Rio Grande. A Tropical Storm Watch is in effect from south of the mouth of the Rio Grande to Boca de Catan, Mexico. GOES-16 captured this geocolor image of Tropical Storm Harvey in the Gulf of Mexico this morning, August 24, 2017. Geocolor imagery enhancement shown here displays geostationary satellite data in different ways depending on whether it is day or night. This image, captured as daylight moves into the area, offers a blend of both, with nighttime features on the left side of the image and daytime on the right. Credit: NOAA/NASA GOES Project

77 FR 42699 - Gulf of Mexico Fishery Management Council; Public Hearings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-20

... INFORMATION. ADDRESSES: The public hearings will be held in the following locations: Tampa, Key West and..., telephone: (251) 344-5200. Wednesday, August 8, 2012 Harvey Government Center, 1200 Truman Avenue, Key West...

Our underpinnings: a bicentennial view. The 1975 Harvey Cushing oration.

PubMed

McCracken, P W

1975-11-01

The author describes the emergence of the liberal traditions which is the foundation of the political and economic systems in this country and considers policies that may affect our social and economic future.

Arsenic and selenium in soils and shallow ground water in the Turtle Lake, New Rockford, Harvey Pumping, Lincoln Valley, and LaMoure irrigation areas of the Garrison Diversion Unit, North Dakota

USGS Publications Warehouse

Berkas, W.R.; Komor, S.C.

1996-01-01

The Garrison Diversion Unit project was authorized as part of the Pick-Sloan Missouri River Basin program to divert water from Lake Sakakawea to irrigation areas in North Dakota. A special Garrison Commission was created to evaluate an environmental concern that return flow from the irrigation areas might contain metals in toxic concentrations. This report summarizes the results of detailed investigations of the Turtle Lake, New Rockford, Harvey Pumping, Lincoln Valley, and LaMoure irrigation areas. A total of 223 soil samples were collected from the irrigation areas and analyzed for elemental composition. Water extractions were done on 40 of the 223 soil samples using a 1:5 soil-to-water extraction method, and the solution from the extraction was analyzed for elemental composition. A total of 52 ground-water samples were collected and analyzed for inorganic constituents and organic carbon.Average arsenic concentrations in the entire soil column ranged from 1.0 milligram per kilogram in the Harvey Pumping irrigation area to 70 milligrams per kilogram in the New Rockford irrigation area. Average selenium concentrations ranged from less than 0.1 milligram per kilogram in the Turtle Lake, New Rockford, Harvey Pumping, and Lincoln Valley irrigation areas to 6.0 milligrams per kilogram in the Turtle Lake irrigation area. In the Turtle Lake irrigation area, average arsenic and selenium concentrations generally increased with depth through the topsoil, oxidized soil, and transition soil but decreased in the reduced soil at the bottom of the sampled horizons. Average arsenic concentrations in the New Rockford irrigation area follow the same pattern as in the Turtle Lake irrigation area, but selenium concentrations do not show a clear pattern of variation with depth. In the Harvey Pumping and Lincoln Valley irrigation areas, arsenic and selenium concentrations do not appear to vary systematically with depth. No correlation is shown between the concentrations in soils and soil extracts, indicating that, based on conditions of laboratory soil-water extraction experiments, trace-element concentrations in soils are not good predictors of trace-element concentrations in irrigation return flow. Arsenic concentrations in the aquifers ranged from less than 1 microgram per liter to 27 micrograms per liter. Arsenic concentrations generally were larger in the deep part of the aquifers underlying the Turtle Lake and New Rockford irrigation areas than in the shallow part of the aquifers. In the shallow part of the aquifers, where oxidizing conditions prevail, arsenic is strongly adsorbed to soil particles. In the deep part of the aquifers, where reducing conditions prevail, arsenic is more mobile.Selenium concentrations in the aquifers ranged from less than 1 microgram per liter to 4 micrograms per liter. Little difference existed between the selenium concentrations in the shallow part of the aquifers underlying the irrigation areas and the concentrations in the deep part of the aquifers.

Simulation-guided cardiac auscultation improves medical students' clinical skills: the Pavia pilot experience.

PubMed

Perlini, Stefano; Salinaro, Francesco; Santalucia, Paola; Musca, Francesco

2014-03-01

Clinical evaluation is the cornerstone of any cardiac diagnosis, although excessive over-specialisation often leads students to disregard the value of clinical skills, and to overemphasize the approach to instrumental cardiac diagnosis. Time restraints, low availability of "typical" cardiac patients on whom to perform effective bedside teaching, patients' respect and the underscoring of the value of clinical skills all lead to a progressive decay in teaching. Simulation-guided cardiac auscultation may improve clinical training in medical students and residents. Harvey(©) is a mannequin encompassing more than 50 cardiac diagnoses that was designed and developed at the University of Miami (Florida, USA). One of the advantages of Harvey(©) simulation resides in the possibility of listening, comparing and discussing "real" murmurs. To objectively assess its teaching performance, the capability to identify five different cardiac diagnoses (atrial septal defect, normal young subject, mitral stenosis with tricuspid regurgitation, chronic mitral regurgitation, and pericarditis) out of more than 50 diagnostic possibilities was assessed in 523 III-year medical students (i.e. at the very beginning of their clinical experience), in 92 VI-year students, and in 42 residents before and after a formal 10-h teaching session with Harvey(©). None of them had previously experienced simulation-based cardiac auscultation in addition to formal lecturing (all three groups) and bedside teaching (VI-year students and residents). In order to assess the "persistence" of the acquired knowledge over time, the test was repeated after 3 years in 85 students, who did not repeat the formal 10-h teaching session with Harvey(©) after the III year. As expected, the overall response was poor in the "beginners" who correctly identified 11.0 % of the administered cardiac murmurs. After simulation-guided training, the ability to recognise the correct cardiac diagnoses was much better (72.0 %; p < 0.001 vs. baseline). Rather unexpectedly, before the tutorial, the performance of VI-year students and of residents was not significantly different from their III-year colleagues, since the two groups correctly identified 14.2 and 16.2 % of the diagnoses, respectively. After the tutorial, the VI-year students and the residents also improved their overall performance (to 73.1 and 76.1 %, respectively; p < 0.001 for both when compared to before the tutorial). The persistence of this capability after 3 years was remarkable, since the 85 students who repeated the test without any further exposure to the 10-h teaching session with Harvey(©) correctly identified 68.4 % of the possible cardiac diagnoses (p < 0.001 vs. baseline). These data underscore the importance of clinical training in order to improve auscultation skills in our academic setting, prompting to redesign teaching curricula. Simulation-based cardiac auscultation should be considered as the "missing link" between formal lecturing and bedside teaching of heart sounds and murmurs.

A more complete picture of mental health legislation.

PubMed

Kettles, Alyson

2010-09-22

As research and development officer for mental health at NHS Grampian, I was interested to read Ian Harvey's article on the implementation of the Mental Health Act 2007 in England and Wales (art&science August 25).

Administrative Relief for Grantees impacted by Hurricanes Harvey, Irma, and Maria

EPA Pesticide Factsheets

On October 26, 2017, the Office of Management and Budget issued the attached memorandum, Administrative Relief for Grantees impacted by Hurricanes, to provide Federal agencies with flexibility to assist their grant applicants and recipients.

Updated NASA Satellite Flood Map of Southeastern Texas (ALOS-2 Data)

NASA Image and Video Library

2017-08-31

The Advanced Rapid Imaging and Analysis (ARIA) team at NASA's Jet Propulsion Laboratory in Pasadena, California, used synthetic aperture radar imagery from the Japan Aerospace Exploration Agency's (JAXA) ALOS-2 satellite to create this Flood Proxy Map depicting areas of Southeastern Texas that are likely flooded as a result of Hurricane Harvey (shown by light blue pixels). The map is derived images taken before (July 30, 2017) and after (Aug. 27, 2017) Hurricane Harvey made landfall. The map covers an area of 220 by 400 miles (350 by 640 kilometers). Each pixel measures about 55 yards (50 meters) across. Local ground observations provided anecdotal preliminary validation. The results are also cross-validated with ARIA Sentinel-1 flood proxy map v0.2. The map should be used as guidance, and may be less reliable over urban areas. ALOS-2 data were accessed through the International Charter. https://photojournal.jpl.nasa.gov/catalog/PIA21931

The Great Scientists

NASA Astrophysics Data System (ADS)

Meadows, Jack

1989-11-01

This lively history of the development of science and its relationship to society combines vivid biographies of twelve pivotal scientists, commentary on the social and historical events of their time, and over four hundred illustrations, including many in color. The biographies span from classical times to the Atomic Age, covering Aristotle, Galileo, Harvey, Newton, Lavoisier, Humboldt, Faraday, Darwin, Pasteur, Curie, Freud, and Einstein. Through the biographies and a wealth of other material, the volume reveals how social forces have influenced the course of science. Along with the highly informative color illustrations, it contains much archival material never before published, ranging from medieval woodcuts, etchings from Renaissance anatomy texts, and pages from Harvey's journal, to modern false-color x-rays and infrared photographs of solar flares. A beautifully-designed, fact-filled, stimulating work, The Great Scientists will fascinate anyone with an interest in science and how history can influence scientific discovery.

Epigenesis and the rationality of nature in William Harvey and Margaret Cavendish.

PubMed

Goldberg, Benjamin

2017-06-01

The generation of animals was a difficult phenomenon to explain in the seventeenth century, having long been a problem in natural philosophy, theology, and medicine. In this paper, I explore how generation, understood as epigenesis, was directly related to an idea of rational nature. I examine epigenesis-the idea that the embryo was constructed part-by-part, over time-in the work of two seemingly dissimilar English philosophers: William Harvey, an eclectic Aristotelian, and Margaret Cavendish, a radical materialist. I chart the ways that they understood and explained epigenesis, given their differences in philosophy and ontology. I argue for the importance of ideas of harmony and order in structuring their accounts of generation as a rational process. I link their experiences during the English Civil war to how they see nature as a possible source for the rationality and concord sorely missing in human affairs.

Thermospheric Airglow Perturbations in the Upper Atmosphere Caused by Hurricane Harvey

NASA Astrophysics Data System (ADS)

Bhatt, A.; Kendall, E. A.

2017-12-01

The Midlatitude Allsky imaging Network for Geophysical Observations (MANGO) consists of seven allsky imagers distributed across the United States recording observations of large-scale airglow perturbations. The imagers are filtered at 630 nm, a forbidden oxygen line, in order to record the predominant source of airglow at 250 km altitude. While the ubiquitous airglow layer is challenging to observe when under uniform conditions, waves in the upper atmosphere cause ripples in the airglow layer which can easily be imaged by appropriate instrumentation. MANGO is the first network to record perturbations in the airglow layer on a continent-size scale. Large and Mid-scale Traveling Ionospheric Disturbances (LSTIDs and MSTIDs) are recorded that are caused by auroral forcing, mountain turbulence, and tidal variations. On August 25, airglow perturbations centered on the Hurricane Harvey path were observed by MANGO. These images and connections to other complimentary data sets such as GPS will be presented.

Hurricane Harvey Building Damage Assessment Using UAV Data

NASA Astrophysics Data System (ADS)

Yeom, J.; Jung, J.; Chang, A.; Choi, I.

2017-12-01

Hurricane Harvey which was extremely destructive major hurricane struck southern Texas, U.S.A on August 25, causing catastrophic flooding and storm damages. We visited Rockport suffered severe building destruction and conducted UAV (Unmanned Aerial Vehicle) surveying for building damage assessment. UAV provides very high resolution images compared with traditional remote sensing data. In addition, prompt and cost-effective damage assessment can be performed regardless of several limitations in other remote sensing platforms such as revisit interval of satellite platforms, complicated flight plan in aerial surveying, and cloud amounts. In this study, UAV flight and GPS surveying were conducted two weeks after hurricane damage to generate an orthomosaic image and a DEM (Digital Elevation Model). 3D region growing scheme has been proposed to quantitatively estimate building damages considering building debris' elevation change and spectral difference. The result showed that the proposed method can be used for high definition building damage assessment in a time- and cost-effective way.

On the Observation of Convection in Late Type Stars

NASA Astrophysics Data System (ADS)

Vázquez Ramió, H.; Régulo, C.; Roca Cortés, T.; Alonso, R.

2004-10-01

Helioseismology of disk-integrated sunlight has shown that the background of the acoustic power spectrum is dominated by structures present in the solar convection zone (Pallé et al., 1995, Régulo et al., 2002). Moreover, using Harvey's model (Harvey et al., 1993) for granulation and supergranulation it has been possible to explain such solar background spectrum on physical grounds. The aim of this work is to establish if this background spectrum can be measured for stars other than the Sun. To evaluate such a possibility we have studied the power spectra of several Main Sequence (MS) stars observed for 54 nights using STARE telescope (Brown and Charbonneau, 1999). Although the observed spectra are dominated by the observing window, preliminary results are very promising since the spectra of F, G and K stars are clearly different from each other, as should be expected from theoretically predicted depths of the convection zones.

Health assessment for Harvey and Knott Drum National Priorities List (NPL) Site, New Castle County, Delaware, Region 3. CERCLIS No. DED980713093. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The Harvey Knott Drum National Priorities List site, located near Kirkwood in New Castle County, Delaware, is an inactive landfill that had received sanitary, municipal and industrial wastes. Contaminants released from the site include heavy metals and organic compounds and have entered groundwater, soils, sediments, and surface waters. The principal concern is that contaminated groundwater may migrate to off-site domestic, public, and agricultural water supply wells. Also, contaminants in off-site surface water and sediments pose some concern for recreational use and consumption of fish. Off-site contaminated soils near the west property line may be a threat to persons that trespassmore » into that area. The site is of potential health concern because of the risk to human health resulting from possible exposure to hazardous substances at concentrations that may result in adverse health effects.« less

Extent of Texas Flooding Shown in New NASA Map

NASA Image and Video Library

2017-08-30

The Advanced Rapid Imaging and Analysis (ARIA) team at NASA's Jet Propulsion Laboratory in Pasadena, California, created this Flood Proxy Map depicting areas of Southeastern Texas that are likely flooded as a result of Hurricane Harvey, shown by light blue pixels. The map is derived from synthetic aperture radar amplitude images from the Japan Aerospace Exploration Agency's (JAXA) ALOS-2 PALSAR-2 satellite, taken before (July 30, 2017) and after (August 27, 2017) Hurricane Harvey made landfall. The map covers an area of 135 square miles (350 square kilometers). Each pixel measures about 538 square feet (50 square meters). Local ground observations provided anecdotal preliminary validation. This flood proxy map should be used as guidance to identify areas that are likely flooded, and may be less reliable over urban areas. ALOS-2 data were accessed through the International Charter. https://photojournal.jpl.nasa.gov/catalog/PIA21928

Evolution of the transfer function characterization of surface scatter phenomena

NASA Astrophysics Data System (ADS)

Harvey, James E.; Pfisterer, Richard N.

2016-09-01

Based upon the empirical observation that BRDF measurements of smooth optical surfaces exhibited shift-invariant behavior when plotted versus    o , the original Harvey-Shack (OHS) surface scatter theory was developed as a scalar linear systems formulation in which scattered light behavior was characterized by a surface transfer function (STF) reminiscent of the optical transfer function (OTF) of modern image formation theory (1976). This shift-invariant behavior combined with the inverse power law behavior when plotting log BRDF versus log   o was quickly incorporated into several optical analysis software packages. Although there was no explicit smooth-surface approximation in the OHS theory, there was a limitation on both the incident and scattering angles. In 1988 the modified Harvey-Shack (MHS) theory removed the limitation on the angle of incidence; however, a moderate-angle scattering limitation remained. Clearly for large incident angles the BRDF was no longer shift-invariant as a different STF was now required for each incident angle. In 2011 the generalized Harvey-Shack (GHS) surface scatter theory, characterized by a two-parameter family of STFs, evolved into a practical modeling tool to calculate BRDFs from optical surface metrology data for situations that violate the smooth surface approximation inherent in the Rayleigh-Rice theory and/or the moderate-angle limitation of the Beckmann-Kirchhoff theory. And finally, the STF can be multiplied by the classical OTF to provide a complete linear systems formulation of image quality as degraded by diffraction, geometrical aberrations and surface scatter effects from residual optical fabrication errors.

Are recent hurricane (Harvey, Irma, Maria) disasters natural?

NASA Astrophysics Data System (ADS)

Trenberth, K. E.; Lijing, C.; Jacobs, P.; Abraham, J. P.

2017-12-01

Yes and no! Hurricanes are certainly natural, but human-caused climate change is supersizing them, and unbridled growth is exacerbating risk of major damages. The addition of heat-trapping gases to the atmosphere has led to observed increases in upper ocean heat content (OHC). This human-caused increase in OHC supports higher sea surface temperatures (SSTs) and atmospheric moisture. These elevated temperatures and increased moisture availability fuel tropical storms, allowing them to grow larger, longer lasting, and more intense, and with widespread heavy rainfalls. Our preliminary analysis of OHC through the August of 2017 shows not only was it by far the highest on record globally, but it was also the highest on record in the Gulf of Mexico prior to hurricane Harvey occurring. The human influence on the climate is also evident in rising sea levels, which increases risks from storm surges. These climatic changes are taking place against a background of growing habitation along coasts, which further increases the risk storms pose to life and property. This combination of planning choice and climatic change illustrates the tragedy of global warming, as evidenced by Harvey in Houston, Irma in the Caribbean and Florida, and Maria in Puerto Rico. However, future damages and loss of life can be mitigated, by stopping or slowing human-caused climate change, and through proactive planning (e.g., better building codes, increased-capacity drainage systems, shelters, and evacuation plans). We discuss the climatic and planning contexts of the unnatural disasters of the 2017 Atlantic Hurricane season, including novel indices of climate-hurricane influence.

75 FR 6218 - Notice of Availability of Draft Director's Order Concerning National Park Service (NPS) Policies...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-08

... Harvey, Chief, Park Facility Management Division, 1849 C Street, NW., Washington, DC 20240, or to his.... Dated: December 9, 2009. Stephen E. Whitesell, Associate Director, Park Planning, Facilities, and Lands...

76 FR 40617 - Drawbridge Operation Regulation; Gulf Intracoastal Waterway, Near Hackberry, LA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-11

...) vertical lift bridge across the Gulf Intracoastal Waterway, mile 243.8 west of Harvey Lock, near Hackberry... work from the operating schedule for the vertical lift bridge on the SR 27 (Ellender Ferry) across the...

DETAIL OF WATER INTAKES FOR FIREFIGHTING SYSTEM ON STARBOARD SIDE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

DETAIL OF WATER INTAKES FOR FIREFIGHTING SYSTEM ON STARBOARD SIDE OF BOAT UNDER THE WATERLINE. ZINCS ARE ALSO ADDED HERE TO PRESERVE THE METAL. - Fireboat JOHN J. HARVEY, Pier 63, North River, New York County, NY

In Memoriam

NASA Astrophysics Data System (ADS)

Robert D. Elliott died on 12 April 2002, at age 87. He was a retired life member (Atmospheric Sciences) who joined AGU in 1944.Karen Harvey died on 30 April 2002, at age 59. She had been an AGU member (Heliospheric Physics) since 1992.

Impacts of a large array of offshore wind farms on precipitation during hurricane Harvey

NASA Astrophysics Data System (ADS)

Pan, Y.; Archer, C. L.

2017-12-01

Hurricane Harvey brought to the Texas coast possibly the heaviest rain ever recorded in U.S. history, which then caused flooding at unprecedented levels. Previous studies have shown that large arrays of offshore wind farms can extract kinetic energy from a hurricane and thus reduce the wind and storm surge. This study will quantitatively test weather the offshore turbines may also affect precipitation patterns. The Weather Research Forecast model is employed to model Harvey and the offshore wind farms are parameterized as elevated drag and turbulence kinetic energy sources. The turbines (7.8 MW Enercon-126 with rotor diameter D=127 m) are placed along the coast of Texas and Louisiana within 100 km from the shore, where the water depth is below 200 meters. Three spacing between turbines are considered (with the number of turbines in parenthesis): 7D×7D (149,936), 9D×9D (84,339), and 11D×11D (56,226). A fourth case (9D×9D) with a smaller area and thus less turbines (33,363) is added to the simulations to emphasize the impacts of offshore turbines installed specifically to protect the city of Houston, which was flooded heavily during hurricane Harvey. The model is integrated for 24 hours from 00UTC Aug 26th, 2017 to 00UTC Aug 27th, 2017. Model results indicate that the offshore wind farms have a strong impact on the distribution of 24-hour accumulated precipitation, with an obvious decrease onshore, downstream of the wind farms, and an increase in the offshore areas, upstream of or within the wind farms. A sector covering the metro-Houston area is chosen to study the sensitivity of the four different wind farm layouts. The spatial-average 24-hour accumulated precipitation is decreased by 37%, 28%, 20% and 25% respectively for the four cases. Compared with the control case with no wind turbines, increased horizontal wind divergence and lower vertical velocity are found where the precipitation is reduced onshore, whereas increased horizontal wind convergence and higher vertical velocity occur upstream or within the offshore wind farms. These preliminary results suggest that large arrays of offshore wind turbines can effectively protect the coast from heavy rain during hurricanes and that smart layouts with fewer turbines over smaller areas can be almost as effective as those with more turbines over larger areas.

The impact of local land subsidence and global sea level rise on flood severity in Houston-Galveston caused by Hurricane Harvey

NASA Astrophysics Data System (ADS)

Miller, M. M.; Shirzaei, M.

2017-12-01

Category-4 Hurricane Harvey had devastating socioeconomic impacts to Houston, with flooding far past the 100-year flood zones published by FEMA. In recent decades, frequency and intensity of coastal flooding are escalating, correlated with sea level rise (SLR). Moreover, Local land subsidence (LLS) due to groundwater and hydrocarbon extraction and natural compaction changes surface elevation and slope, potentially altering drainage patterns. GPS data show a mm broad co-cyclonic subsidence due to elastic loading from the water mass measured by GPS, which is inverted to solve for the total fluid volume of 2.73x1010 m3. We additionally investigate the joint impact of an SLR and pre-cyclonic LLS on the flooding of Houston-Galveston during Hurricane Harvey. We examine vertical land motion within North American Vertical Datum 2012 for the period 2007 until the cyclone by investigating SAR imaged acquired by ALOS and Sentinel-1A/B radar satellites combined with GPS data. We find patchy, LLS bowls resulting in sinks where floodwater can collect. We map the flooding extent by comparing amplitudes of Sentinal1-A/B pixels' backscattered radar signal from pre- and post-Harvey acquisitions and estimate 782 km2 are submerged within the area of 3478 km2 of pixels covered by Sentinel frame. Comparing with the LLS map, 89% of the flooded pixels exhibit -3 mm/yr or greater vertical motion. Flooding attributed to the storm surge is determined with high-resolution LiDAR digital elevation models (DEM) and a 0.75 m storm tide inundation model, which engulfs only 195 km2 and nearby the shorelines. We estimate future inundation hazard by combining LiDAR DEMs with our InSAR derived subsidence map, projecting LLS rates forward 100 years, and modeling projected SLR from 0.4 to 1.2 meters. Were subsidence to continue unabated, the total flooded area is 281 km2 with a 0.4 m and 394 km2 with a 1.2 m SLR. Next, we add a modest storm tide (0.752 m), which increases the flooded area to 389 - 480 km2. The combined effects of LLS and SLR are important to evaluate flood resilience strategies.

Geotechnical Impacts of Hurricane Harvey Along the Texas, USA Coast

NASA Astrophysics Data System (ADS)

Smallegan, S. M.; Stark, N.; Jafari, N.; Ravichandran, N.; Shafii, I.; Bassal, P.; Figlus, J.

2017-12-01

As part of the NSF-funded Geotechnical Extreme Events Reconnaissance (GEER) Association response to Hurricane Harvey, a team of engineers and scientists mobilized to the coastal cities of Texas, USA from 1 to 5 September 2017. Damage to coastal and riverine structures due to erosion by storm surge, waves, and coastal and riverine flooding was assessed in a wide coastal zone between Corpus Christi and Galveston. Making initial landfall near Rockport, Texas on 26 August 2017, Hurricane Harvey was classified as a category 4 hurricane on the Saffir-Simpson scale with wind speeds exceeding 130 mph and an atmospheric pressure of 938 mbar. The storm stalled over the Houston area, pouring 40 inches of rain on an area encompassing more than 3,000 square miles. Hurricane Harvey, which remained a named storm for 117 hours after initial landfall, slowly moved east into the Gulf of Mexico and made final landfall near Cameron, Louisiana on 30 August. The GEER team surveyed sixteen main sites, extending from Mustang Island in the southwest to Galveston in the northeast and as far inland as Rosenburg. In Port Aransas, beach erosion and undercutting along a beach access road near Aransas Pass were observed. Due to several tide gauge failures in this area, the nearest NOAA tide gauge (#8775870 near Corpus Christi) was used to estimate water levels of 1.35 m, approximately 1.0 m above the predicted tide. In Holiday Beach, anchored retaining walls were inundated, causing backside scour along the entire length and exposing the sheetpile wall anchors. Along the Colorado River at the Highway 35 bridge near Bay City, active riverbank failure was observed and a sheet pile wall was found collapsed. Significant sediment deposits lined the vegetated riverbanks. A USGS stream gage recorded gage heights greater than 45 ft, exceeding the flood stage of 44 ft. Fronting a rubblemound seawall in Surfside Beach, a runnel and ridge formation was observed. Nearby at San Luis Pass, infilled scour around bridge piers and beach erosion were observed. Sediment samples, penetrometer, and mini torvane data were collected at most of these sites and data analysis is being conducted. The presentation will provide an overview of the findings of the GEER team. The preliminary report may be found at www.geerassociation.org.

Real-Time Tracking of the Extreme Rainfall of Hurricanes Harvey, Irma, and Maria using UCI CHRS's iRain System

NASA Astrophysics Data System (ADS)

Shearer, E. J.; Nguyen, P.; Ombadi, M.; Palacios, T.; Huynh, P.; Furman, D.; Tran, H.; Braithwaite, D.; Hsu, K. L.; Sorooshian, S.; Logan, W. S.

2017-12-01

During the 2017 hurricane season, three major hurricanes-Harvey, Irma, and Maria-devastated the Atlantic coast of the US and the Caribbean Islands. Harvey set the record for the rainiest storm in continental US history, Irma was the longest-lived powerful hurricane ever observed, and Maria was the costliest storm in Puerto Rican history. The recorded maximum precipitation totals for these storms were 65, 16, and 20 inches respectively. These events provided the Center for Hydrometeorology and Remote Sensing (CHRS) an opportunity to test its global real-time satellite precipitation observation system, iRain, for extreme storm events. The iRain system has been under development through a collaboration between CHRS at the University of California, Irvine (UCI) and UNESCO's International Hydrological Program (IHP). iRain provides near real-time high resolution (0.04°, approx. 4km) global (60°N - 60°S) satellite precipitation data estimated by the PERSIANN-Cloud Classification System (PERSIANN-CCS) algorithm developed by the scientists at CHRS. The user-interactive and web-accessible iRain system allows users to visualize and download real-time global satellite precipitation estimates and track the development and path of the current 50 largest storms globally from data generated by the PERSIANN-CCS algorithm. iRain continuously proves to be an effective tool for measuring real-time precipitation amounts of extreme storms-especially in locations that do not have extensive rain gauge or radar coverage. Such areas include large portions of the world's oceans and over continents such as Africa and Asia. CHRS also created a mobile app version of the system named "iRain UCI", available for iOS and Android devices. During these storms, real-time rainfall data generated by PERSIANN-CCS was consistently comparable to radar and rain gauge data. This presentation evaluates iRain's efficiency as a tool for extreme precipitation monitoring and provides an evaluation of the PERSIANN-CCS real-time rainfall estimates during Hurricanes Harvey, Irma, and Maria in relation to radar and rain gauge data using continuous (correlation, root mean square error, and bias) and categorical (POD and FAR) indices. These results present the relative skill of PERSIANN-CCS real-time data to radar and rain gauge data.

Ecohydrological Responses to Hurricane Harvey across South-Central Texas a Multidisciplinary Approach of the Texas Water Observatory

NASA Astrophysics Data System (ADS)

Jaimes, A.; Gaur, N.; Aparecido, L. M. T.; Everett, M. E.; Knappett, P.; Lawing, M.; Majumder, S.; Miller, G. R.; Moore, G. W.; Morgan, C.; Mitra, B.; Noormets, A.; Mohanty, B.

2017-12-01

The unprecedented destructive hurricane Harvey struck eastern Texas from August 25th to 29th, 2017. As the hurricane moved through the region, it dropped the equivalent of one year of precipitation within a five-day period, with peak accumulations near 165 cm. Rainfall intensity and distribution varied across the region but Harris County and portions of the lower Brazos River Basin experienced devastating flooding due to high run-off and water accumulation in the built-up area. In this study, we use a multidisciplinary approach to quantify the dynamics of carbon and water flux at different spatiotemporal resolution across land types both in and outside of the path of hurricane Harvey using a combination of remote sensing and fixed monitoring platforms of the Texas Water Observatory (TWO). We used LANDSAT imagery to compute Soil Adjusted Vegetation Index, Enhanced Vegetation Index, and Normalized Difference Moisture Index. MODIS ET, GPP, and sap flow data were used in combination with eddy covariance and meteorological data from seven sites of the TWO representative of biomes ranging from low tidal salt marsh of the Gulf Coastal Plain, Shrubland, Improved Pasture, Mixed and Native Prairies, and Crop sites. We hypothesize alteration in ecohydrological characteristics across land types, which were in the path of hurricane due to changes in vegetation structure. Specifically we used trend analysis to detect structural changes in temporal dynamics of sap flow, ET, and carbon to pulse response. In addition, we monitored trace metal concentration of soil and water pores before and immediately after the hurricane in order to predict the potential of any of the toxic metal (loid)s being mobilized in the natural water resources as a function of the changes in the redox gradient. Preliminary results indicated that tree water use was reduced on average 30% below normal days. Porewater concentration of some of the metal (loid) concentration increased (Fe, Mn, Co, As, Sb, Pb) from pre- to post-hurricane scenario. Overall, the integrative approach adopted by TWO in evaluating the impact of Hurricane Harvey on ecosystem structure and function has the potential to provide the baseline information to manage and mitigate the effects of future events with similar characteristics.

Language Identification by Statistical Analysis

DTIC Science & Technology

1974-09-01

Porter, Katherine Anne, The Grave. Schwartz, Delmore, In Dreams Begin Responsibilities. Steele, Wilbur Daniel, Footfalls. Steinbeck, John, from The...Isaac Bashevis, Esther Kreindel The Second. Swados, Harvey, A Story For Teddy. Updike, John, The Lucid Eye in Silver Town. White, Robin, Walker’s

39. VIEW TO NORTHEAST; WEST FRONT MBE BUILDING, FIRST FLOOR, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

39. VIEW TO NORTHEAST; WEST FRONT MBE BUILDING, FIRST FLOOR, FRED HARVEY NEWSSTAND STOREROOM (AREA BURNED BY VANDALS) (Dobson) - Los Angeles Union Passenger Terminal, Mail, Baggage, & Express Building, 800 North Alameda Street, Los Angeles, Los Angeles County, CA

Shock Waves and the Origin of Life

DTIC Science & Technology

1977-01-01

Augustine, St. Thomas Aquinas, Alexander Neckham, Cardinal Damien, Paracelsus, Goethe, Copernicus , Galileo, Harvey, Francis Bacon, Descartes, Hegel and... astronomy and geology. It became thus quite inevitable that the question of how life originated be reopened and examined again in view of the newly

PROBABILISTIC MONITORING FOR TRIBAL AQUATIC RESOURCE: EPA'S NATIONAL COASTAL ASSESSMENT TRIBAL TRAINING

EPA Science Inventory

Harvey, James, David Lawes, Vincent Cooke and Tom Heitmuller. In press. Probabilistic Monitoring for Tribal Aquatic Resources: EPA's National Coastal Assessment Tribal Training (Abstract). To be presented at the Monitoring Science and Technology Symposium, 20-24 September 2004, D...

Fecal Calprotectin in Ileal Crohn's Disease: Relationship with Magnetic Resonance Enterography and a Pathology Score.

PubMed

Cerrillo, Elena; Beltrán, Belén; Pous, Salvador; Echarri, Ana; Gallego, Jose Carlos; Iborra, Marisa; Pamies, Jose; Nos, Pilar

2015-07-01

Magnetic resonance enterography (MRE) is an effective method of assessing small bowel Crohn's disease (CD). Fecal calprotectin (FC) correlates well with endoscopic disease activity. We aimed to evaluate the correlation between FC and disease activity according to MRE and surgical pathology in small bowel CD. One hundred twenty consecutive patients with ileal CD who underwent MRE assessment were included. Clinical data, C-reactive protein and FC, radiological and histological variables were obtained. Clinical activity was evaluated by the Harvey-Bradshaw Index and FC by enzyme-linked immunosorbent assay. MRE activity was assessed by means of the Magnetic Resonance Index of Activity score. Chiorean's score was used to grade pathological inflammation in surgical specimens. Seventy-five patients (62.5%) were in clinical remission (Harvey-Bradshaw Index < 5) and 45 (37.5%) had active disease (Harvey-Bradshaw Index ≥ 5). The Magnetic Resonance Index of Activity score was significantly associated with FC levels (P < 0.01), with a moderate overall correlation (Spearman's r = 0.56, P < 0.001). FC reflected MRE inflammatory activity with an area under the receiver operating characteristic curve of 0.914 (confidence interval, 0.849-0.958; P < 0.001). A cutoff value of 166.50 μg/g had 90% sensitivity, 74% specificity, 89% positive predictive value, and 76% negative predictive value for diagnosis of inflammation. Twenty-eight of 120 patients were operated. Surgical pathology showed a good agreement with FC for moderate (P = 0.03) and severe (P = 0.01) Chiorean's index. No relationship was detected for C-reactive protein. FC correlates with the degree of MRE inflammatory activity and with surgical pathology damage in ileal CD. Thus, FC could be a surrogate marker of disease control used to select patients for MRE assessment and therapeutic adjustment.

Hurricane Harvey rapid response: observations of infragravity wave dynamics and morphological change during inundation of a barrier island cut

NASA Astrophysics Data System (ADS)

Anarde, K.; Figlus, J.; Dellapenna, T. M.; Bedient, P. B.

2017-12-01

Prior to landfall of Hurricane Harvey on August 25, 2017, instrumentation was deployed on the seaward and landward sides of a barrier island on the central Texas Gulf Coast to collect in-situ hydrodynamic measurements during storm impact. High-resolution devices capable of withstanding extreme conditions included inexpensive pressure transducers and tilt current meters mounted within and atop (respectively) shallow monitoring wells. In order to link measurements of storm hydrodynamics with the morphological evolution of the barrier, pre- and post-storm digital elevation models were generated using a combination of unmanned aerial imagery, LiDAR, and real-time kinematic GPS. Push-cores were collected and analyzed for grain size and sedimentary structure to relate hydrodynamic observations with the local character of storm-generated deposits. Observations show that at Hog Island, located approximately 160 miles northeast of Harvey's landfall location, storm surge inundated an inactive storm channel. Infragravity waves (0.003 - 0.05 Hz) dominated the water motion onshore of the berm crest over a 24-hour period proximate to storm landfall. Over this time, approximately 50 cm of sediment accreted vertically atop the instrument located in the backshore. Storm deposits at this location contained sub-parallel alternating laminae of quartz and heavy mineral-enriched sand. While onshore progression of infragravity waves into the back-barrier was observed over several hours prior to storm landfall, storm deposits in the back-barrier lack the characteristic laminae preserved in the backshore. These field measurements will ultimately be used to constrain and validate numerical modeling schemes that explore morphodynamic conditions of barriers in response to extreme storms (e.g., XBeach, CSHORE). This study provides a unique data set linking extreme storm hydrodynamics with geomorphic changes during a relatively low surge, but highly dissipative wave event.

Stalling Tropical Cyclones over the Atlantic Basin

NASA Astrophysics Data System (ADS)

Nielsen-Gammon, J. W.; Emanuel, K.

2017-12-01

Hurricane Harvey produced massive amounts of rain over southeast Texas and southwest Louisiana. Average storm total rainfall amounts over a 10,000 square mile (26,000 square km) area exceeded 30 inches (750 mm). An important aspect of the storm that contributed to the large rainfall totals was its unusual motion. The storm stalled shortly after making landfall, then moved back offshore before once again making landfall five days later. This storm motion permitted heavy rainfall to occur in the same general area for an extended period of time. The unusual nature of this event motivates an investigation into the characteristics and potential climate change influences on stalled tropical cyclones in the Atlantic basin using the HURDAT 2 storm track database for 1866-2016 and downscaled tropical cyclones driven by simulations of present and future climate. The motion of cyclones is quantified as the size of a circle circumscribing all storm locations during a given length of time. For a three-day period, Harvey remained inside a circle with a radius of 123 km. This ranks within the top 0.6% of slowest-moving historical storm instances. Among the 2% of slowest-moving storm instances prior to Harvey, only 13 involved storms that stalled near the continental United States coast, where they may have produced substantial rainfall onshore while tapping into marine moisture. Only two such storms stalled in the month of September, in contrast to 20 September stalls out of the 36 storms that stalled over the nearby open Atlantic. Just four of the stalled coastal storms were hurricanes, implying a return frequency for such storms of much less than once per decade. The synoptic setting of these storms is examined for common features, and historical and projected trends in occurrences of stalled storms near the coast and farther offshore are investigated.

Partial enteral nutrition with a Crohn's disease exclusion diet is effective for induction of remission in children and young adults with Crohn's disease.

PubMed

Sigall-Boneh, Rotem; Pfeffer-Gik, Tamar; Segal, Idit; Zangen, Tsili; Boaz, Mona; Levine, Arie

2014-08-01

Exclusive enteral nutrition is effective for inducing remission in active pediatric Crohn's disease. Partial enteral nutrition (PEN) with free diet is ineffective for inducing remission, suggesting that the mechanism depends on exclusion of free diet. We developed an alternative diet based on PEN with exclusion of dietary components hypothesized to affect the microbiome or intestinal permeability. Children and young adults with active disease defined as a pediatric Crohn's disease activity index >7.5 or Harvey-Bradshaw index ≥4 received a 6-week structured Crohn's disease exclusion diet that allowed access to specific foods and restricted exposure to all other foods, and up to 50% of dietary calories from a polymeric formula. Remission, C-reactive protien, and erythrocyte sedimentation rate were reevaluated at 6 weeks. The primary endpoint was remission at 6 weeks defined as Harvey-Bradshaw index ≤3 for all patients and pediatric Crohn's disease activity index <7.5 in children. We treated 47 patients (mean age, 16.1 ± 5.6 yr; 34 children). Response and remission were obtained in 37 (78.7%) and 33 (70.2%) patients, respectively. Mean pediatric Crohn's disease activity index decreased from 27.7 ± 9.4 to 5.4 ± 8 (P < 0.001), Harvey-Bradshaw index from 6.4 ± 2.7 to 1.8 ± 2.9 (P < 0.001). Remission was obtained in 70% of children and 69% of adults. Normalization of previously elevated CRP occurred in 21 of 30 (70%) patients in remission. Seven patients used the diet without PEN; 6 of 7 obtained remission. Dietary therapy involving PEN with an exclusion diet seems to lead to high remission rates in early mild-to-moderate luminal Crohn's disease in children and young adults.

Harvey Cushing, the spine surgeon: the surgical treatment of Pott disease.

PubMed

Bydon, Ali; Dasenbrock, Hormuzdiyar H; Pendleton, Courtney; McGirt, Matthew J; Gokaslan, Ziya L; Quinones-Hinojosa, Alfredo

2011-08-01

Review of historical archival records. Describe Harvey Cushing's patients with spinal pathology. Harvey Cushing was a pioneer of modern surgery but his work on spine remains largely unknown. Review of the Chesney Medical Archives of the Johns Hopkins Hospital from 1896 to 1912. This is the first time that Cushing's spinal cases while he was at the Johns Hopkins Hospital, including those with Pott disease, have been described.Cushing treated three young men with psoas abscesses secondary to Pott disease during his residency: he drained the abscesses, debrided any accompanying necrotic vertebral bodies, irrigated the cavity with salt, and left the incision open to close by secondary intention. Although Cushing used Koch's "tuberculin therapy" (of intravenous administration of isolated tubercular bacilli) in one patient, he did not do so in the other two, likely because of the poor response of this first patient. Later in his tenure, Cushing performed a laminectomy on a patient with kyphosis and paraplegia secondary to Pott disease. These cases provide a view of Cushing early in his career, pointing to the extraordinary degree of independence that he had during his residency under William Steward Halsted; these cases may have been important in the surgical upbringing both of Cushing and his coresident, William Stevenson Baer, who became the first professor of Orthopedics at Johns Hopkins Hospital. At the turn of the last century, Pott disease was primarily treated by immobilization with bed rest, braces, and plaster-of-paris jackets; some surgeons also employed gradual correction of the deformity by hyperextension. Patients who failed a trial of conservative therapy (of months to years) were treated with a laminectomy. However, the limitations of these strategies led to the development of techniques that form the basis of contemporary spine surgery-instrumentation and fusion.

Hurricane Harvey Riverine Flooding: Part 2: Integration of Heterogeneous Earth Observation Data for Comparative Analysis with High-Resolution Inundation Boundaries Reconstructed from Flood2D-GPU Model

NASA Astrophysics Data System (ADS)

Jackson, C.; Sava, E.; Cervone, G.

2017-12-01

Hurricane Harvey has been noted as the wettest cyclone on record for the US as well as the most destructive (so far) for the 2017 hurricane season. An entire year worth of rainfall occurred over the course of a few days. The city of Houston was greatly impacted as the storm lingered over the city for five days, causing a record-breaking 50+ inches of rain as well as severe damage from flooding. Flood model simulations were performed to reconstruct the event in order to better understand, assess, and predict flooding dynamics for the future. Additionally, number of remote sensing platforms, and on ground instruments that provide near real-time data have also been used for flood identification, monitoring, and damage assessment. Although both flood models and remote sensing techniques are able to identify inundated areas, rapid and accurate flood prediction at a high spatio-temporal resolution remains a challenge. Thus a methodological approach which fuses the two techniques can help to better validate what is being modeled and observed. Recent advancements in data fusion techniques of remote sensing with near real time heterogeneous datasets have allowed emergency responders to more efficiently extract increasingly precise and relevant knowledge from the available information. In this work the use of multiple sources of contributed data, coupled with remotely sensed and open source geospatial datasets is demonstrated to generate an understanding of potential damage assessment for the floods after Hurricane Harvey in Harris County, Texas. The feasibility of integrating multiple sources at different temporal and spatial resolutions into hydrodynamic models for flood inundation simulations is assessed. Furthermore the contributed datasets are compared against a reconstructed flood extent generated from the Flood2D-GPU model.

An In Depth Look at Lightning Trends in Hurricane Harvey using Satellite and Ground-Based Measurements

NASA Astrophysics Data System (ADS)

Ringhausen, J.

2017-12-01

This research combines satellite measurements of lightning in Hurricane Harvey with ground-based lightning measurements to get a better sense of the total lightning occurring in the hurricane, both intra-cloud (IC) and cloud-to-ground (CG), and how it relates to the intensification and weakening of the tropical system. Past studies have looked at lightning trends in hurricanes using the space based Lightning Imaging Sensor (LIS) or ground-based lightning detection networks. However, both of these methods have drawbacks. For instance, LIS was in low earth orbit, which limited lightning observations to 90 seconds for a particular point on the ground; hence, continuous lightning coverage of a hurricane was not possible. Ground-based networks can have a decreased detection efficiency, particularly for ICs, over oceans where hurricanes generally intensify. With the launch of the Geostationary Lightning Mapper (GLM) on the GOES-16 satellite, researchers can study total lightning continuously over the lifetime of a tropical cyclone. This study utilizes GLM to investigate total lightning activity in Hurricane Harvey temporally; this is augmented with spatial analysis relative to hurricane structure, similar to previous studies. Further, GLM and ground-based network data are combined using Bayesian techniques in a new manner to leverage the strengths of each detection method. This methodology 1) provides a more complete estimate of lightning activity and 2) enables the derivation of the IC:CG ratio (Z-ratio) throughout the time period of the study. In particular, details of the evolution of the Z-ratio in time and space are presented. In addition, lightning stroke spatiotemporal trends are compared to lightning flash trends. This research represents a new application of lightning data that can be used in future study of tropical cyclone intensification and weakening.

Lignans from the seeds of Chinese hawthorn (Crataegus pinnatifida var. major N.E.Br.) against β-amyloid aggregation.

PubMed

Huang, Xiao-Xiao; Xu, Yang; Bai, Ming; Zhou, Le; Song, Shao-Jiang; Wang, Xiao-Bo

2017-11-08

Phytochemical investigation on the seeds of hawthorn (Crataegus spp.) led to the isolation of a new compound, (7'R, 8'R, 8S)-isolariciresinol (1), along with six known compounds (2-7). The structures of all compounds were determined based on spectroscopic data interpretation. The Aβ 1-42 inhibition activity of all isolated compounds was evaluated in vitro. As a result, compounds 5 and 6 showed stronger inhibition of Aβ 1-42 aggregation than curcumin, with inhibition rates of 70.59 and 68.14% at 20 μM. The possible mechanism of interaction between Aβ 1-42 and the active compounds 5 and 6 was also investigated by molecular docking.

ARC-2009-ACD09-0141-006

NASA Image and Video Library

2009-07-16

A plaque presented to Harvey Allen in recognition of his outstanding solution of the reentry heating problem which has been indispensable to the design of the Mercury, Gemini, and Apollo spacecraft (Manned Spacecraft Center, November 14, 1968) Plaque contains samples of tested materials and models of spacecraft.

76 FR 70829 - Proposed Information Collection (Architect-Engineer Fee Proposal) Activity; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-15

... (Architect--Engineer Fee Proposal) Activity; Comment Request AGENCY: Veterans Health Administration, Department of Veterans Affairs. ACTION: Notice. SUMMARY: The Veterans Health Administration (VHA), Department... Docket Management System (FDMS) at www.Regulations.gov or to Cynthia Harvey-Pryor, Veterans Health...

Indigenous Education, Colonization, Neoliberal Schools, and Narratives of Survivance

ERIC Educational Resources Information Center

Burns, Jim; Nolan, Jaime; Weston, Ernest, Jr.; Malcolm, Amanda

2016-01-01

Framed in Foucault's theorization of governmentality and drawing on Harvey's scholarship on neoliberalism and Arvin, Tuck, and Morrill's critical analysis of heteropatriarchal settler colonialism, we theorize a historical linkage between colonizing education and neoliberal schooling. Against that historical backdrop, Ernest and Amanda, two Native…

75 FR 51832 - Kansas; Major Disaster and Related Determinations

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-23

... determinations. DATES: Effective Date: August 10, 2010. FOR FURTHER INFORMATION CONTACT: Peggy Miller, Recovery... Hazard Mitigation will be limited to 75 percent of the total eligible costs. Further, you are authorized... Atchison, Brown, Butler, Chase, Clay, Cloud, Comanche, Doniphan, Ellis, Franklin, Greenwood, Harvey, Jewell...

Progress in Mathematical Programming.

DTIC Science & Technology

1987-03-04

Philip Gill, Neal Glassman, Donald Goldfarb, Clovis Gonzaga, Harvey Greenberg , Peter Gritzmann, James K. Ho, Alan Hoffman, T. C. Hu, Hiroshi Imai...polar polytope P’ if 0 E P. The image trajectories are geodesics of a projectively invariant geometry on P 0 , Hilbert geometry. This work relates

Instructional Media.

ERIC Educational Resources Information Center

Journal of College Science Teaching, 1984

1984-01-01

Reviews a six-part series (available as 16mm film or videocassettes) in which actors portray scientists lecturing on various topics/issues. Scientists portrayed include Louis Pasteur, Charles Darwin, William Harvey, Gregor Mendel, William Beaumont, and Hans Spemann. Also reviews a film detailing construction of the Multiple Mirror Telescope on…

Furthering the Enzymatic Destruction of Nerve Agents

DTIC Science & Technology

2002-01-01

properties of an organophosphorus acid anhydrase from a halophilic bacterial isolate. J. Bacteriol. 173, 1938-1943. DeFrank, J.J.; Beaudry, W.T...Cheng, T.-c.; Harvey, S.P.; Stroup, A.N. and Szafraniec, L.L. (1993) Screening of halophilic bacteria and Alteromonas species for organophosphorus

Lessons from the history of medicine.

PubMed

Waller, John

2008-01-01

What is the point of teaching the history of medicine? Many historians and clinicians find it regrettable that some medical students today will graduate knowing almost nothing of such "greats" of the past as Hippocrates, Galen, Vesalius, Harvey, Lister, and Pasteur. But does this really matter? After all, traditional history of medicine curricula tended to distort medicine's past, omitting the countless errors, wrong turns, fads, blunders, and abuses, in order to tell the sanitized stories of a few scientific superheroes. Modern scholarship has seriously challenged most of these heroic dramas; few of our heroes were as farsighted, noble, or obviously correct as once thought. Joseph Lister, for example, turns out to have had filthy wards, whereas William Harvey was devoted to the Aristotelianism he was long said to have overthrown [1]. But as the history of medicine has become less romanticized, it has also become much more relevant, for it promises to impart useful lessons in the vital importance of scientific scepticism.

New NASA Satellite Flood Map of Southeastern Texas (Sentinel-1 Data)

NASA Image and Video Library

2017-08-31

The Advanced Rapid Imaging and Analysis (ARIA) team at NASA's Jet Propulsion Laboratory in Pasadena, California, used synthetic aperture radar imagery from the European Space Agency's (ESA) Sentinel-1 satellite to create this Flood Proxy Map of Southeastern Texas, showing areas that are likely flooded as a result of Hurricane Harvey (light blue pixels). The images used to create the map were taken before (Aug. 5, 2017) and after (Aug. 29, 2017) Hurricane Harvey made landfall. The map covers an area of 155 by 211 miles (250 by 340 kilometers). Each pixel measures about 33 yards (30 meters) across. Local ground observations provided anecdotal preliminary validation. The results were also cross-validated with the ARIA ALOS-2 flood proxy map v0.2. The map should be used as guidance, and may be less reliable over urban areas. Sentinel-1 data were accessed through the Copernicus Open Access Hub. Contains modified Copernicus Sentinel data 2017. https://photojournal.jpl.nasa.gov/catalog/PIA21932

Harvey Cushing and some Australian connections: Part 2--post World War 1.

PubMed

Roxanas, M G

2010-03-01

Part 1 of this article (see Vol 17, pp. 168-172) described the early life of Harvey Cushing and his encounters with Australian doctors, mostly in various military hospitals, in France, in World War 1. As none of the doctors he met at that time became neurosurgeons, and hence did not shape their professional development. When World War 1 ended, HC returned to a heavy schedule of operating at the Peter Bent Brigham Hospital and to his university obligations. He received the Companion of the Bath from the British Government for his war services and wrote the history of US Base Hospital No. 5, which he directed during the War. Cushing's reputation as a neurosurgeon was now secure and he was ready to play an even greater part as an academic neurosurgeon, teaching students from all parts of the world and continuing his researches into cerebral tumours and the pituitary gland. Copyright 2009 Elsevier Ltd. All rights reserved.

Harvey Cushing's ghosts: death and hauntings in modern medicine.

PubMed

Shin, Paul

2011-06-01

The passing of Yale School of Medicine's 2010 Bicentennial occasions a moment of reflecting on the past, present, and future of medical education and research at Yale and beyond. Last June, a ribbon-cutting ceremony inaugurated the opening of the Cushing Center in the Cushing-Whitney Medical Library. Named after Harvey Cushing, an early 20th-century neurosurgeon and former Yale College alum, the dual education/exhibition space now houses hundreds of gross brain specimens constituting the Cushing Tumor Registry. Originally a personal collection, Cushing donated his numerous medical specimens, photographs, and other medical relics from his deathbed, relinquishing the brains to Yale only under the condition that a suitable space be erected to preserve the many specimens. Some 70 years later and after nearly being destroyed, Cushing's wish is fully realized: The once desiccated, hidden brains have been painstakingly restored and are now on view in the Cushing Center. The brains express Cushing's singular and spectral worldview as a surgeon, artist, athlete, soldier, book collector, and historian.

Book Review: Maxwell's Demon 2: Entropy, classical and quantum information, computing. Harvey Leff and Andrew Rex (Eds.); Institute of Physics, Bristol, 2003, 500pp., US 55, ISBN 0750307595

NASA Astrophysics Data System (ADS)

Shenker, Orly R.

2004-09-01

In 1867, James Clerk Maxwell proposed a perpetuum mobile of the second kind, that is, a counter example for the Second Law of thermodynamics, which came to be known as "Maxwell's Demon." Unlike any other perpetual motion machine, this one escaped attempts by the best scientists and philosophers to show that the Second Law or its statistical mechanical counterparts are universal after all. "Maxwell's demon lives on. After more than 130 years of uncertain life and at least two pronouncements of death, this fanciful character seems more vibrant than ever." These words of Harvey Leff and Andrew Rex (1990), which open their introduction to Maxwell's Demon 2: Entropy, Classical and Quantum Information, Computing (hereafter MD2) are very true: the Demon is as challenging and as intriguing as ever, and forces us to think and rethink about the foundations of thermodynamics and of statistical mechanics.

Complete mitochondrial genome of the brown alga Sargassum fusiforme (Sargassaceae, Phaeophyceae): genome architecture and taxonomic consideration.

PubMed

Liu, Feng; Pang, Shaojun; Luo, Minbo

2016-01-01

Sargassum fusiforme (Harvey) Setchell (=Hizikia fusiformis (Harvey) Okamura) is one of the most important economic seaweeds for mariculture in China. In this study, we present the complete mitochondrial genome of S. fusiforme. The genome is 34,696 bp in length with circular organization, encoding the standard set of three ribosomal RNA genes (rRNA), 25 transfer RNA genes (tRNA), 35 protein-coding genes, and two conserved open reading frames (ORFs). Its total AT content is 62.47%, lower than other brown algae except Pylaiella littoralis. The mitogenome carries 1571 bp of intergenic region constituting 4.53% of the genome, and 13 pairs of overlapping genes with the overlap size from 1 to 90 bp. The phylogenetic analyses based on 35 protein-coding genes reveal that S. fusiforme has a closer evolutionary relationship with Sargassum muticum than Sargassum horneri, indicating Hizikia are not distinct evolutionary entity and should be reduced to synonymy with Sargassum.

Harvey Cushing’s Ghosts: Death and Hauntings in Modern Medicine

PubMed Central

Shin, Paul

2011-01-01

The passing of Yale School of Medicine’s 2010 Bicentennial occasions a moment of reflecting on the past, present, and future of medical education and research at Yale and beyond. Last June, a ribbon-cutting ceremony inaugurated the opening of the Cushing Center in the Cushing-Whitney Medical Library. Named after Harvey Cushing, an early 20th-century neurosurgeon and former Yale College alum, the dual education/exhibition space now houses hundreds of gross brain specimens constituting the Cushing Tumor Registry. Originally a personal collection, Cushing donated his numerous medical specimens, photographs, and other medical relics from his deathbed, relinquishing the brains to Yale only under the condition that a suitable space be erected to preserve the many specimens. Some 70 years later and after nearly being destroyed, Cushing’s wish is fully realized: The once desiccated, hidden brains have been painstakingly restored and are now on view in the Cushing Center. The brains express Cushing’s singular and spectral worldview as a surgeon, artist, athlete, soldier, book collector, and historian. PMID:21698039

Superfund at work: Hazardous waste cleanup efforts nationwide, Spring 1993 (Harvey and Knott Drum Site, New Castle County, Delaware)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

From 1963 to 1969, two acres of the Harvey and Knott Drum site in New Castle County, Delaware served as an open dump and burning area for sanitary, municipal, and industrial wastes. Sludge, paint pigment, and solvents contaminated the site until the State of Delaware and the US Environmental Protection Agency (EPA) intervened in 1981. Site conditions required a combination of traditional cleanup measures. After the immediate health threats posed by the site were eliminated, EPA reached an innovative, mixed funding settlement for long-term cleanup with two parties responsible for the site contamination. The following actions highlight the success ofmore » the Superfund program: An emergency removal of contaminants reduced immediate environmental and public health effects; A rapid assessment of ground water safeguarded drinking water supplies; and The full cooperation of General Motors (GM) expedited implementation of the cleanup, valued at $3.2 million.« less

PILOT PROJECT CLOSE UP: ORD RESEARCH INVENTORY

EPA Science Inventory

Harvey, Jim and Elin Ulrich. 2004. Pilot Project Close Up: ORD Research Inventory. Changing Times. Pp. 1. (ERL,GB R1022).

At the January 2003 summit, many people were drawn to our vision of improving ORD's internal communications by creating a "go-to" page that consolicat...

Educational Reform: A Deweyan Perspective. Critical Educational Practice. Volume 10.

ERIC Educational Resources Information Center

Simpson, Douglas J.; Jackson, Michael J. B.

This book re-examines the reflective, controversial voice of John Dewey. Educators and policymakers must take into account various social, political, economic, philosophical, and professional considerations that influence both formal and informal education. Following the introduction by Harvey Neufeldt called "School Reform in Dewey's…

Disinfection Alternatives for Small Communities in Puerto Rico

EPA Science Inventory

Disinfection Alternatives for Small Communities in Puerto Rico Craig Patterson1, Graciela Ramirez Toro2, Harvey Minnigh2, Cristina Maldonado3, and Rajib Sinha4 1U.S. EPA Office of Research and Development, 2Centro de Educación, Conservación e Interpretación Ambiental (CECIA),...

Insurers Relax Rules, Help Members After Hurricanes Harvey, Irma.

PubMed

Greene, Jan

2017-10-01

Some health plans responded by making it easier to see an out-of-network doctor, get a new copy of an insurance card or replace prescriptions lost in the chaos. Insurers also set up telephone help lines and made it easier to get a referral to a specialist.

CMMI on the Web: Remastered

DTIC Science & Technology

2009-09-01

Patrick Kirwin: www.sei.cmu.edu/library/abstracts/webinars/18jul2008.cfm  Also see: www.sei.cmu.edu/prime  ISO 9001/15504/ 12207 /15288 Process...Improvement with CMMI V1.2 and ISO Standards by Boris Mutafelija and Harvey Stromberg (Book)  www.sei.cmu.edu/library/abstracts/presentations/Mutafelija

50 CFR 36.39 - Public use.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., and Swanson Lakes are only open for sport ice fishing. Andy Simons Unit Emerald Lake Green Lake Harvey... sport ice fishing. South of Sterling Highway Headquarters Lake is restricted to administrative use only..., Chickaloon (upstream of river mile 7.5), Killey, and Fox Rivers. (v) A “no-wake” restriction applies to...

50 CFR 36.39 - Public use.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., and Swanson Lakes are only open for sport ice fishing. Andy Simons Unit Emerald Lake Green Lake Harvey... sport ice fishing. South of Sterling Highway Headquarters Lake is restricted to administrative use only..., Chickaloon (upstream of river mile 7.5), Killey, and Fox Rivers. (v) A “no-wake” restriction applies to...

50 CFR 36.39 - Public use.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., and Swanson Lakes are only open for sport ice fishing. Andy Simons Unit Emerald Lake Green Lake Harvey... sport ice fishing. South of Sterling Highway Headquarters Lake is restricted to administrative use only..., Chickaloon (upstream of river mile 7.5), Killey, and Fox Rivers. (v) A “no-wake” restriction applies to...

ARC-2009-ACD09-0141-001

NASA Image and Video Library

2009-07-16

John W. 'Jack Boyd holds a plaque presented to Harvey Allen in recognition of his outstanding solution of the reentry heating problem which has been indispensable to the design of the Mercury, Gemini, and Apollo spacecraft (Manned Spacecraft Center, November 14, 1968) Plaque contains samples of tested materials and models of spacecraft.

Texturing Space-Times in the Australian Curriculum: Cross-Curriculum Priorities

ERIC Educational Resources Information Center

Peacock, David; Lingard, Robert; Sellar, Sam

2015-01-01

The Australian curriculum, as a policy imagining what learning should take place in schools, and what that learning should achieve, involves the imagining and rescaling of social relations amongst students, their schools, the nation-state and the globe. Following David Harvey's theorisations of space-time and Norman Fairclough's operationalisation…

A More Perfect Commodity: Bottled Water, Global Accumulation, and Local Contestation

ERIC Educational Resources Information Center

Jaffee, Daniel; Newman, Soren

2013-01-01

Bottled water sits at the intersection of debates regarding the social and environmental effects of the commodification of nature and the ways neoliberal globalization alters the provision of public services. Utilizing Polanyi's concept of fictitious commodities and Harvey's work on accumulation by dispossession, this article traces bottled…

Mapping the Classroom Emotional Environment

ERIC Educational Resources Information Center

Harvey, Shane T.; Bimler, David; Evans, Ian M.; Kirkland, John; Pechtel, Pia

2012-01-01

Harvey and Evans (2003) have proposed that teachers' emotional skills, as required in the classroom, can be organized into a five-dimensional model. Further research is necessary to validate this model and evaluate the importance of each dimension of teacher emotion competence for educational practice. Using a statistical method for mapping…

50 CFR 36.39 - Public use.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., and Swanson Lakes are only open for sport ice fishing. Andy Simons Unit Emerald Lake Green Lake Harvey..., waysides, buildings or the Sterling Highway from the east refuge boundary to the east junction of the... buildings, piers, docks, weirs, refuge offices, visitor centers, and public access and parking sites. Maps...

Student Perspectives on Quality in Higher Education

ERIC Educational Resources Information Center

Jungblut, Jens; Vukasovic, Martina; Stensaker, Bjørn

2015-01-01

The study provides an insight into student perspectives on quality in higher education, using Harvey and Green conceptualizations as the point of departure, and exploring the linkages between the views on quality, the developments of the Bologna Process and related national reforms, as well as students' motivation for and expectations from higher…

Learning from the Past, Building for the Future

ERIC Educational Resources Information Center

Brand, Noreen B.

2013-01-01

The Illinois Holocaust Museum and Education Center (IHMEC) strives to engage youth as citizens through "Make a Difference! The Harvey L. Miller Family Youth Exhibition." Teaching about the Holocaust is complex and challenging work. Holocaust education is mandated in Illinois elementary and high schools, yet the Museum finds that many…

Critical Thinking, Autonomy and Practical Reason

ERIC Educational Resources Information Center

Cuypers, Stefaan E.

2004-01-01

This article points out an internal tension, or even conflict, in the conceptual foundations of Harvey Siegel's conception of critical thinking. Siegel justifies critical thinking, or critically rational autonomy, as an educational ideal first and foremost by an appeal to the Kantian principle of respect for persons. It is made explicit that this…

The Program Is Aristotelian

ERIC Educational Resources Information Center

Shulman, Harvey

2002-01-01

Three faculty members of Concordia University in Montreal, who played integral roles in the formation of a highly successful core curriculum as part of their institution, discuss the logistics, the politics, and the philosophy behind the founding and growth of their Liberal Arts College. For Harvey Shulman, the program, which has attracted…

75 FR 78601 - Drawbridge Operation Regulation; Gulf Intracoastal Waterway, New Orleans Harbor, Inner Harbor...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-16

... Operation Regulation; Gulf Intracoastal Waterway, New Orleans Harbor, Inner Harbor Navigation Canal, New Orleans, Orleans Parish, LA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from... Harvey Lock), at New Orleans, Orleans Parish, Louisiana. This deviation is necessary to adjust the...

77 FR 75556 - Drawbridge Operation Regulation; Gulf Intracoastal Waterway, Louisiana

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-21

... Route, Gulf Intracoastal Waterway (GIWW), mile 2.8 at New Orleans, Jefferson Parish, Louisiana. The... Span Bridge across the Harvey Canal Route, Intracoastal Waterway, mile 2.8 at New Orleans, Jefferson.... Department of Transportation, West Building Ground Floor, Room W12-140, 1200 New Jersey Avenue SE...

78 FR 14185 - Drawbridge Operation Regulation; Gulf Intracoastal Waterway, LA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-05

... Intracoastal Waterway (GIWW), mile 2.8 at New Orleans, Jefferson Parish, Louisiana. The deviation is necessary... across the Harvey Canal Route, Intracoastal Waterway, mile 2.8 at New Orleans, Jefferson Parish... Department of Transportation West Building, 1200 New Jersey Avenue SE., Washington, DC 20590, between 9 a.m...

Gaining Perspective on Parenting Groups.

ERIC Educational Resources Information Center

Fenichel, Emily, Ed.

1996-01-01

This theme issue offers a collection of articles focusing on support groups for parents of infants and toddlers, including the following: (1) "Gaining Perspective on Parenting Groups" (Nick Carter and Cathie Harvey) which reviews the purposes, history, and essential ingredients of such groups; (2) "The MELD Experience with Parent Groups" (Joyce…

Nova Southeastern University (NSU) Guy Harvey Oceanographic Center

Science.gov Websites

Mailman Segal Center for Human Development Ron and Kathy Assaf College of Nursing Shepard Broad College of . Continuing Education Financial Aid Career Development Regional Campuses International Affairs Veterans Arts and culture on campus including theatre, music, and art. Campus Housing Off-Campus Housing Campus

75 FR 4269 - Establishment of Class E Airspace; Hertford, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-27

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2009-0705; Airspace Docket No. 09-ASO-25] Establishment of Class E Airspace; Hertford, NC AGENCY: Federal... September 14, 2009 that establishes Class E Airspace at Harvey Point Defense Testing Activity, Hertford, NC...

Minimizing the Pervasiveness of Women's Personal Experiences of Gender Discrimination

ERIC Educational Resources Information Center

Foster, Mindi D.; Jackson, Lydia C.; Hartmann, Ryan; Woulfe, Shannon

2004-01-01

Given the Rejection-Identification Model (Branscombe, Schmitt, & Harvey, 1999), which shows that perceiving discrimination to be pervasive is a negative experience, it was suggested that there would be conditions under which women would instead minimize the pervasiveness of discrimination. Study 1 (N= 91) showed that when women envisioned…

More Value to Defining Quality

ERIC Educational Resources Information Center

Van Kemenade, Everard; Pupius, Mike; Hardjono, Teun W.

2008-01-01

There are lots of definitions of quality, and also of quality in education. Garvin (1984) discerns five approaches: the transcendental approach, the product-oriented approach, the customer-oriented approach, the manufacturing-oriented approach and the value-for-money approach. Harvey and Green (1993) give five interrelated concepts of quality as:…

Parental Conceptual Systems, Home Play Environment, and Potential Creativity in Children.

ERIC Educational Resources Information Center

Bishop, Doyle W.; Chace, Charles A.

Parents differing along a concreteness-abstractness dimension of conceptual development, as defined by the model of Harvey, Hunt, and Schroder, described their attitudes and practices regarding their children's home play environment. This was done using structured questionnaires. Potential creativity of the 3- and 4-year-old children themselves…

Training Program for Instrumentation, Telemetry, and Exercise Ergometry

DTIC Science & Technology

1990-11-01

Maj Sauber . This will allow a constant-rate infusion of pyridostigmine. After a surgical level of anesthesia has been reached with ketamine (15 mg/kg...Effects") under the supervision of Lieutenant Colonel Fanton, Major Harvey, or Major Sauber . After a surgical level of anesthesia has been reached with keta

Further Food for Thought on the "ABS Guide"

ERIC Educational Resources Information Center

Hussain, Simon

2012-01-01

This paper replies to points raised by the editors of the "ABS Guide", Huw Morris, Charles Harvey, Aidan Kelly and Michael Rowlinson (2011) "Accounting Education: an international journal", 20(6), pp. 561-573) in response to a paper published in a previous issue of "Accounting Education" (Hussain, S. (2011)…

75 FR 79393 - Notice of Lodging of Settlement Agreement Under the Comprehensive Environmental Response...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-20

... Liquidation Corporation, formerly known as General Motors Corporation, Remediation and Liability Management Company, Inc., and Environmental Corporate Remediation Company, Inc. (collectively, ``Old GM''); and the... Settlement Agreement, Old GM will make a cash payment of $2,484,816 to EPA for remediation at the Harvey...

Deaf-Blind Perspectives. 1996-97.

ERIC Educational Resources Information Center

Deaf-Blind Perspectives, 1996

1996-01-01

Three issues of this newsletter include articles on and news items related to deaf-blindness. Articles include the following: "Research-to-Practice: Bridging the Gap between Research and Demonstration Projects and Practical Needs of Parents and Educators" (Harvey Mar and Nancy Sall); "Syndromes, Behavior, and Educational Intervention" (J. P. M.…

Terms of Inclusion: Unity and Diversity in Public Education

ERIC Educational Resources Information Center

Kantor, Harvey; Lowe, Robert

2007-01-01

In this review essay, Harvey Kantor and Robert Lowe explore the history of the culture wars in public education in the United States. Drawing on three books--David Tyack's "Seeking Common Ground," Jonathan Zimmerman's "Whose America?" and Amy Binder's "Contentious Curricula"--Kantor and Lowe review the history of…

After the Storm: Helping Children Cope with Trauma after Natural Disasters

ERIC Educational Resources Information Center

Simmons, Krystal T.; Douglas, Denika Y.

2018-01-01

Though adults undoubtedly suffer tremendous stress in the aftermath of natural disasters such as Hurricanes Harvey, Irma, and Maria, it is often the most vulnerable, the children, who are most traumatized and possess the fewest coping skills. Signs of child psychological trauma such as symptoms commonly associated with posttraumatic stress…

Objectivism, Rhetoric, and Ancient Egyptian Logic: Still More Questions

ERIC Educational Resources Information Center

Meltzer, Edmund S.

2008-01-01

It is contended that in Harvey Pegues's essay on objectivism and constructivism in the summer 2007 issue of "The Educational Forum", Pegues conducted an intellectual discourse in which legitimate or good-faith disagreement was not an option, and disparaged and imputed the negative motives with which he disagreed. This article responds by pointing…

Outstanding student paper

NASA Astrophysics Data System (ADS)

One presentation was named Outstanding Student Paper in the Planetology Section at the 1993 Fall Meeting in San Francisco.C. David Brown, who presented “Sub-Alternative Models for the Formation of Artemis Chasma,” is a doctoral student at Arizona State University, Tempe. He received his B.S. in physics at Harvey Mudd College, Claremont, Calif., in 1991

The White Majority: Between Poverty and Affluence.

ERIC Educational Resources Information Center

Howe, Louise Kapp, Ed.

Contents of this book include: "Introduction," Louise Kapp Howe; "The revolt of the white lower-middle class," Pete Hamill; "Life with Cappelli on $101 a week," Harvey Aronson; "Blue-collar marriages and families," Mirra Komarovsky; "Working-class youth: alienation without an image," William Simon and John H. Gagnon; "Greasers, Dupers and Hippies:…

78 FR 76398 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-17

... W. Foster (TN), Francis M. Garlach, III (PA), Darren L. Graham (TX), James M. Harvey (OH), Jerry D...), Richard D. Stalter (AR), Charles W. Sterling (WA), and Carl F. Wagner, Jr. (IN) from the ITDM requirement... applications, FMCSA exempts Toni Benfield (SC), Delbert L. Bennett, Jr. (ID), Daniel A. Bryan (PA), Stephen A...

Corporate Schooling and Decorative Metrics: The Iconography of Academy School Chains in England

ERIC Educational Resources Information Center

Holligan, Chris

2017-01-01

The continuation of neo-liberalism requires concerted effort. Political consent is constructed through practices of enforced cultural socialisation, the mobilisations of which obfuscate other realities. David Harvey describes this process as the construction of consent. The common sense encouraged by English academy schools is the result of the…

The Corpus Status of Literature in Teaching Sociology: Novels as "Sociological Reconstruction"

ERIC Educational Resources Information Center

Carlin, Andrew P.

2010-01-01

Using fiction in teaching sociology involves what Harvey Sacks calls "sociological reconstruction". Numerous comments on teaching sociology provide advice and suggestions on the use of literature and "what counts" as "sociological" literature, including specific titles. This paper goes further: while the use of literature is a routine feature of…

Community College Professional Development: Sharing What Works. Proceedings of a National Conference (San Antonio, Texas, October 18-19, 1991).

ERIC Educational Resources Information Center

Faulkner, Susan L.; And Others

This document contains 30 papers on professional development in community colleges. The following papers are included: "Effective Leadership Strategies for Planning and Implementing Tech Prep" (Bragg, Huffman); "Small Business Management-Tech Prep" (Harvey); "Educational Reform and the New Mission" (Hoerner);…

The Concentric Support Model: A Model for the Planning and Evaluation of Distance Learning Programs

ERIC Educational Resources Information Center

Osika, Elizabeth

2006-01-01

Each year, the number of institutions offering distance learning courses continues to grow significantly (Green, 2002; National Center for Educational Statistics, 2003; Wagner, 2000). Broskoske and Harvey (2000) explained that "many institutions begin a distance education initiative encouraged by the potential benefits, influenced by their…

Social Exclusion, Education and Precarity: Neoliberalism, Neoconservatism and Class War from Above

ERIC Educational Resources Information Center

Prendergast, Louise M.; Hill, Dave; Jones, Sharon

2017-01-01

In this article we analyze neoliberalism and neoconservatism, their intentions and characteristics, and the relationship between them. We locate these ideologies and associated policies and discourses as part of the :class war from above" (Harvey, 2005). We critically interrogate the impact of their policies and discourses on the social…

The Politics of Nonliteracy: Logocentrism in the Classroom.

ERIC Educational Resources Information Center

Edwards, Bruce L., Jr.

The conventional notion of the term "literacy" is rather narrow. Harvey Graff's work demonstrates that literacy in Western society not only means the ability to read and write, but also takes in a profusion of values and beliefs including empathy, innovativeness, and achievement. By contrast, a term such as illiterate comes to represent social…

Toleration, Multiculturalism and Mistaken Belief

ERIC Educational Resources Information Center

Standish, Paul

2006-01-01

Doubts have been expressed about the virtue of toleration, especially in view of what some have seen as its complicity with a morality of anything goes. More rigorous arguments have been provided by Peter Gardner and Harvey Siegel against the relativism evident in certain versions of multiculturalism and in the new religious studies. This article…

Biodegradation of Organofluorine Compounds

DTIC Science & Technology

2016-02-01

BIODEGRADATION OF ORGANOFLUORINE COMPOUNDS ECBC-TR-1347 Melissa M. Dixon Steve P. Harvey RESEARCH AND...2011 4. TITLE AND SUBTITLE Biodegradation of Organofluorine Compounds 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR...compounds as sole carbon sources. This work will be continued in future studies. 15. SUBJECT TERMS Organofluorine Biodegradation Defluorination

Consensus report on the future of animal-free systemic toxicity testing

EPA Science Inventory

This is a multi-authored consensus report from conferences held in 2011-2012. Complete author listing is as follows: Marcel Leist1,2, Nina Hasiwa1, Costanza Rovida1, Mardas Daneshian1, David Basketter3, Ian Kimber4, Harvey Clewell5, Tilman Gocht6, Alan Goldberg7, Derek Knight8, G...

Harvey: The Impact of a Cardiovascular Teaching Simulator on Student Skill Acquisition.

ERIC Educational Resources Information Center

Woolliscroft, James O.; And Others

1987-01-01

A life-sized cardiovascular patient simulator was used in medical education in a standard sophomore physical skills test. Significant gains were found in overall student scores and in assessment of interpretation of carotid pulses and precordial auscultation. Students did not make significant gains in jugular venous pulse or precordial motion…

Most Comprehension Tests Do Measure Reading Comprehension: A Response to McLean and Goldstein.

ERIC Educational Resources Information Center

Stenner, A. Jackson; And Others

1988-01-01

Rebuffs Leslie Maclean and Harvey Goldstein's claims that the National Assessment of Educational Progress (NAEP) Reading Proficiency Scale is unidimensional. Critics' confusion may stem from failing to separate what a test measures from a score's usefulness. The Lexile Reading Scale should be integrated with the NAEP scale. Includes eight…

78 FR 79699 - Cellular, Tissue, and Gene Therapies Advisory Committee; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-31

... Harvey, Food and Drug Administration, Center for Biologics Evaluation and Research, 1401 Rockville Pike... Biologics Evaluation and Research (CBER), FDA. On February 26, 2014, from 1 p.m. to approximately 5 p.m... and gene therapy products. CBER published guidance on this topic in July 2013 ( http://www.fda.gov...

Black Achievers in Science, Teachers Guide.

ERIC Educational Resources Information Center

Museum of Science and Industry, Chicago, IL.

In this guide, 16 historical and contemporary black scientists and engineers are highlighted as role models. Four scientists are represented in each of four technical fields: life sciences (Ernest E. Just; Harvey M. Pickrum; George W. Carver; Patricia S. Cowings); physical science (George R. Carruthers; Percy L. Julian; Walter E. Massey; Warren M.…

Critical Thinking and the Critical Person.

ERIC Educational Resources Information Center

Paul, Richard W.

The paper's purpose is to clarify and develop some theoretical and practical implications of the concept of critical thinking, and the field of social studies is used as one example of the problem. The work of four leading critical theorists (Robert Ennis, Harvey Siegel, Michael Scriven, and R. S. Peters) is described and a distinction is made…

Privatization: A Drain on Public Schools

ERIC Educational Resources Information Center

Harvey, James

2012-01-01

According to James Harvey, the scale of the 2011 effort to privatize public education through vouchers and charters is "staggering," representing the culmination of a 30-year assault on public service in general and public education in particular. At a time when states are staring into the abyss of bankruptcy, he notes, public funds intended for…

Neo-Liberalism, Irish Society and Adult Education

ERIC Educational Resources Information Center

Finnegan, Fergal

2008-01-01

This article offers an overview of recent international scholarship on neo-liberalism in particular the work of the geographer and historian David Harvey and the recent books of the educationalist Henry Giroux. It begins with a brief historical account of neo-liberalism and outlines the main characteristics of the free market era. Irish society…

Movie Lessons for New Learning

ERIC Educational Resources Information Center

Saltmarsh, David

2009-01-01

In 2004 the Australia Council of Deans of Education (ACDE) released a report entitled "New teaching, new learning: A vision for Australian education". This report was prepared on behalf of the ACDE by Mary Kalantzis and Andrew Harvey, respectively the President and Executive Officer of the ACDE. The argument put forward in the report is…

Conceiving Education: The Creative Task before Us

ERIC Educational Resources Information Center

Laverty, Megan J.

2014-01-01

Philosophers of education regularly undertake the challenging task of defining their field and what it is they do. John White and Harvey Siegel are no exception: Siegel categorizes philosophy of education as a branch of philosophy, and White responds that philosophers of education would do better to adopt a Deweyan perspective. White claims that…

Philosophy, Philosophy of Education, and Economic Realities

ERIC Educational Resources Information Center

White, John

2013-01-01

In 2009 Harvey Siegel edited "The Oxford Handbook of Philosophy of Education." This article develops a theme, prompted by reflection on several essays in that volume, about the nature of philosophy of education and its relation to philosophy. Siegel's view that philosophy of education is a "branch" of philosophy is put to…

Toxicities of TNT and RDX to Terrestrial Plants in Five Soils with Contrasting Characteristics

DTIC Science & Technology

2013-07-01

C.W.; Wentsel, R.S.; Nwanguma, R.O.; Sadusky, M. Toxicity Determination of Explosive Contaminated Soil Leachates to Daphnia magna Using an Adapted...UNCLASSIFIED Report (ADA270410). Hannink, N.K.; Rosser, S.J.; Bruce, N.C. Phytoremediation of Explosives. Crit. Rev. Plant Sci. 2002, 21, 511–538. Harvey

Harvey Cushing's Meningiomas text and the historical origin of resectability criteria for the anterior one third of the superior sagittal sinus.

PubMed

Shrivastava, Raj K; Segal, Salomao; Camins, Martin B; Sen, Chandranath; Post, Kalmon D

2003-10-01

The search for the origin of the commonly held principle in current neurosurgery regarding the resectability of the anterior one third of the superior sagittal sinus unravels the many fascinating developments that occurred in neurosurgery during the early 20th century. All these occurrences can be traced back to, and are uniquely contextualized in, Harvey Cushing's seminal text, Meningiomas, Their Classification, Regional Behaviour, Life History, and Surgical End Results. Written with Louise Eisenhardt and published in 1938, Meningiomas is a monograph of incredible description and detail. The meticulous categorization of meningiomas, their presentation, clinical outcome, and surgical therapies are even further supplemented by Cushing's personal commentary, questions, and recollections. Cushing's genius was evident in his ability not only to make insightful clinical observations, but also to synthesize these ideas within the neurosurgical context of his era. As he says in Meningiomas, "Thus the pathological curiosity of one day becomes in its proper time a commonplace... most of which are one and the same disorder--had, for their interpretation, to await the advent of the Neurosurgeon."

Constraining Big Hurricanes: Remotely sensing Galveston Islands' changing coastal landscape from days to millennia

NASA Astrophysics Data System (ADS)

Dougherty, A. J.; Choi, J. H.; Heo, S.; Dosseto, A.

2017-12-01

Climate change models forecast increased storm intensity, which will drive coastal erosion as sea-level rise accelerates with global warming. Over the last five years the largest hurricanes ever recorded in the Pacific (Patricia) and the Atlantic (Irma) occurred as well as the devastation of Harvey. The preceding decade was marked with Super Storm Sandy, Katrina and Ike. A century prior, the deadliest natural disaster in North America occurred as a category 4 hurricane known as `The 1900 Storm' hit Galveston Island. This research aims to contextualize the impact of storms long before infrastructure and historical/scientific accounts documented erosion. Unlike the majority of barrier islands in the US, Galveston built seaward over the Holocene. As the beach prograded it preserved a history of storms and shoreline change over millennia to the present-day. These systems (called prograded barriers) were first studied over 50 years ago using topographic profiles, sediment cores and radiocarbon dating. This research revisits some of these benchmark study sites to augment existing data utilizing state-of-the-art Light Detection and Ranging (LiDAR), Ground Penetrating Radar (GPR), and Optically Stimulated Luminescence (OSL) techniques. In 2016 GPR and OSL data were collected from Galveston Island, with the aim to combine GPR, OSL and LiDAR (GOaL) to extract a high-resolution geologic record spanning 6,000 years. The resulting millennia-scale coastal evolution can be used to contextualize the impact of historic hurricanes over the past century (`The 1900 Storm'), decade (Ike in 2008) and year (now with Harvey). Preliminary results reveal a recent change in shoreline behaviour, and data from Harvey are currently being accessed within the perspective of these initial findings. This dataset will be discussed with respect to the other two benchmark prograded barriers studied in North America: Nayarit Barrier (Mexico) that Hurricane Patricia passed directly over in 2013 and Kiawah Barrier (South Carolina), which was ultimately spared from Hurricane Irma 2017.

Attribution of extreme rainfall from Hurricane Harvey, August 2017

NASA Astrophysics Data System (ADS)

van Oldenborgh, Geert Jan; van der Wiel, Karin; Sebastian, Antonia; Singh, Roop; Arrighi, Julie; Otto, Friederike; Haustein, Karsten; Li, Sihan; Vecchi, Gabriel; Cullen, Heidi

2017-12-01

During August 25-30, 2017, Hurricane Harvey stalled over Texas and caused extreme precipitation, particularly over Houston and the surrounding area on August 26-28. This resulted in extensive flooding with over 80 fatalities and large economic costs. It was an extremely rare event: the return period of the highest observed three-day precipitation amount, 1043.4 mm 3dy-1 at Baytown, is more than 9000 years (97.5% one-sided confidence interval) and return periods exceeded 1000 yr (750 mm 3dy-1) over a large area in the current climate. Observations since 1880 over the region show a clear positive trend in the intensity of extreme precipitation of between 12% and 22%, roughly two times the increase of the moisture holding capacity of the atmosphere expected for 1 °C warming according to the Clausius-Clapeyron (CC) relation. This would indicate that the moisture flux was increased by both the moisture content and stronger winds or updrafts driven by the heat of condensation of the moisture. We also analysed extreme rainfall in the Houston area in three ensembles of 25 km resolution models. The first also shows 2 × CC scaling, the second 1 × CC scaling and the third did not have a realistic representation of extreme rainfall on the Gulf Coast. Extrapolating these results to the 2017 event, we conclude that global warming made the precipitation about 15% (8%-19%) more intense, or equivalently made such an event three (1.5-5) times more likely. This analysis makes clear that extreme rainfall events along the Gulf Coast are on the rise. And while fortifying Houston to fully withstand the impact of an event as extreme as Hurricane Harvey may not be economically feasible, it is critical that information regarding the increasing risk of extreme rainfall events in general should be part of the discussion about future improvements to Houston’s flood protection system.

Harvey Cushing, the Spine Surgeon

PubMed Central

Bydon, Ali; Dasenbrock, Hormuzdiyar H.; Pendleton, Courtney; McGirt, Matthew J.; Gokaslan, Ziya L.; Quinones-Hinojosa, Alfredo

2015-01-01

Study Design Review of historical archival records. Objective Describe Harvey Cushing's patients with spinal pathology. Summary of Background Data Harvey Cushing was a pioneer of modern surgery but his work on spine remains largely unknown. Methods Review of the Chesney Medical Archives of the Johns Hopkins Hospital from 1896 to 1912. Results This is the first time that Cushing's spinal cases while he was at the Johns Hopkins Hospital, including those with Pott disease, have been described. Cushing treated three young men with psoas abscesses secondary to Pott disease during his residency: he drained the abscesses, debrided any accompanying necrotic vertebral bodies, irrigated the cavity with salt, and left the incision open to close by secondary intention. Although Cushing used Koch's “tuberculin therapy” (of intravenous administration of isolated tubercular bacilli) in one patient, he did not do so in the other two, likely because of the poor response of this first patient. Later in his tenure, Cushing performed a laminectomy on a patient with kyphosis and paraplegia secondary to Pott disease. Conclusion These cases provide a view of Cushing early in his career, pointing to the extraordinary degree of independence that he had during his residency under William Steward Halsted; these cases may have been important in the surgical upbringing both of Cushing and his coresident, William Stevenson Baer, who became the first professor of Orthopedics at Johns Hopkins Hospital. At the turn of the last century, Pott disease was primarily treated by immobilization with bed rest, braces, and plaster-of-paris jackets; some surgeons also employed gradual correction of the deformity by hyperextension. Patients who failed a trial of conservative therapy (of months to years) were treated with a laminectomy. However, the limitations of these strategies led to the development of techniques that form the basis of contemporary spine surgery—instrumentation and fusion. PMID:21224751

Regional-scale impact of storm surges on groundwaters of Texas, Florida and Puerto Rico after 2017 hurricanes Harvey, Irma, Jose, Maria

NASA Astrophysics Data System (ADS)

Sellier, W. H.; Dürr, H. H.

2017-12-01

Hurricanes and related storm surges have devastating effects on near-shore infrastructure and above-ground installations. They also heavily impact groundwater resources, with potentially millions of people dependant on these resources as a freshwater source. Destructions of casings and direct incursions of saline and/or polluted waters have been widely observed. It is uncertain how extensive the effects are on underground water systems, especially in limestone karst areas such as Florida and Puerto Rico. Here, we report regional-scale water level changes in groundwater systems of Texas, Florida and Puerto Rico for the 2017 Hurricanes Harvey, Irma, Jose and Maria. We collected regional scale data from the USGS Waterdata portal. Puerto Rico shows the strongest increase in groundwater levels in wells during Hurricane Maria, with less reaction for the preceding storms Irma and Jose. Increases in water levels range from 0.5 to 11m, with maximum storm surges in Puerto Rico around 3m. These wells are located throughout Puerto Rico, on the coast and inland. In Florida, most wells that show a response during Hurricane Irma are located in the Miami region. Wells located on the west coast show smaller responses with the exception of one well located directly on Hurricane Irma's track. These wells show an increase of 0.2 to 1.7m. In Texas, wells located in proximity to Hurricane Harvey's track show an increase in water level. The effect of groundwater level increases is not limited to the Texas coast, but inland as well. An increase between 0.03 and 2.9m is seen. Storm surges for both Florida and Texas have ranged from 1.8-3.7m maximum. We discuss the findings in the context of local and regional geology and hydrogeology (presence of connected aquifer systems, faulting, presence of carbonate/karst systems etc.).

Estimating Transient Water Storage from Hurricane Harvey Using GPS Observations of Vertical Land Motion

NASA Astrophysics Data System (ADS)

Milliner, C. W. D.; Materna, K.; Burgmann, R.; Fu, Y.; Bekaert, D. P.; Moore, A. W.; Adhikari, S.

2017-12-01

The Global Positioning System (GPS) measures elastic ground motions due to variations in terrestrial water mass. Such measurements have been used to successfully study variations of hydrological loading over monthly-to-yearly timescales; e.g., seasonal changes in water storage in California (Argus et al., 2014), 3-year drought of Western US (Borsa et al., 2014) and monthly water storage change in the Pacific Northwest (Fu et al., 2015). However, inferring water storage variations from single loading events over daily-to-weekly timescales presents a major challenge, due to the relatively higher level of noise and systematic errors, such as common mode errors (CME). This makes geodetic investigations of transient hydrologic events, such as major hurricanes, particularly difficult. By using daily vertical GPS timeseries we resolve the spatial and temporal evolution of water loading from Hurricane Harvey across the Gulf coast by applying multiple network correction methods, which helps to isolate the hydrological loading signal. Using 340 GPS stations distributed across the southern US, we mitigate for the effects of spatially correlated CME by firstly removing vertical contributions from atmospheric and non-ocean tidal loading, and secondly correcting the residual positions for changes in translation, rotation and scaling using a Helmert transformation. Our results show a maximum subsidence of 1.8 cm occurring around Houston, and a clear migration of land subsidence from Corpus Christi to western Louisiana over a 7-day period, consistent with the movement of Harvey itself. We also present preliminary results using the Network Inversion Filter (Bekaert et al., 2016), in which we use a Kalman filter approach to describe the time-varying water mass in a stochastic sense. Although our results are preliminary, we find removal of systematic sources of noise can help reveal hydrological loading signals due to extreme, transient events, that would typically go missed by other spatially and temporally coarser methods (e.g., GRACE), providing valuable constraints on large and sudden changes to the hydrosphere.

Hurricane Harvey Podcast Update

NASA Image and Video Library

2017-08-30

Houston, We Have a Podcast. Welcome to the official podcast of the NASA Johnson Space Center. I’m Gary Jordan. Well as you probably know, southeast Texas was just slammed with the furious winds and torrential downpour of Hurricane Harvey. A lot of Houstonians were affected by the storm and the 40 + inches of rain that came with it. Some had to evacuate. Some held their ground. Others needed to be rescued on boats and helicopters. And others sadly lost their lives. It was a truly devastating storm. Definitely the most intense weather I’ve ever endured. But if there’s one good thing that came from this disaster, it’s learning that Houston is full of some incredible people, and spaceship Earth is not such a bad place to live. Local first responders and coast guard were helping those in need, and even Texas civilians grabbed their trucks and boats to aid in these efforts. At NASA’s Johnson Space Center, flight controllers braved the weather and camped out in Mission Control 24/7 to make sure the crewmembers aboard the International Space Station were safe and well. Right now, the Johnson Space Center is closed and will reopen after Labor Day on September 5th, 2017. We’ll post the next full episode of “Houston, We Have a Podcast” once the center is back up and running, and later we’ll share some of the science and comprehensive data behind Hurricane Harvey in an episode with NASA experts. Already, we’re looking at soil moisture data with a NASA-NOAA satellite, and there are a lot of other great Earth science studies going on at the space agency. But for now, we Houstonians focus on the community. Our hearts and efforts go out to the families that are affected most and the city that we will rebuild. See you next week.

Ethanol extract of Zhongtian hawthorn lowers serum cholesterol in mice by inhibiting transcription of 3-hydroxy-3-methylglutaryl-CoA reductase via nuclear factor-kappa B signal pathway.

PubMed

Hu, Hai-Jie; Luo, Xue-Gang; Dong, Qing-Qing; Mu, Ai; Shi, Guo-Long; Wang, Qiu-Tong; Chen, Xiao-Ying; Zhou, Hao; Zhang, Tong-Cun; Pan, Li-Wen

2016-03-01

Hawthorn is a berry-like fruit from the species of Crataegus. In China, it has another more famous name, Shan-Zha, which has been used to improve digestion as a traditional Chinese medicine or food for thousands of years. Moreover, during the last decades, hawthorn has received more attention because of its potential to treat cardiovascular diseases. However, currently, only fruits of C. pinnatifida and C. pinnatifida var. major are included as Shan-Zha in the Chinese Pharmacopoeia. In this study, our results showed that the ethanol extract of Zhongtian hawthorn, a novel grafted cultivar of C. cuneata (wild Shan-Zha), could markedly reduce body weight and levels of serum total cholesterol, triglyceride, low-density lipoprotein cholesterol, and liver cholesterol of hyperlipidemia mice. It could suppress the stimulation effect of high-fat diet on the transcription of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) and p65, and counteract the downregulation of CYP7A1 and LDLR. In addition, the results of luciferase reporter assay and Western blot showed that the transcriptional activity of HMGCR promoter was inhibited by Zhongtian hawthorn ethanol extract in a dose-dependent manner, while overexpression of p65 could reverse this transcriptional repression effect. These results suggested that Zhongtian hawthorn could provide health benefits by counteracting the high-fat diet-induced hypercholesteolemic and hyperlipidemic effects in vivo, and the mechanism underlying this event was mainly dependent on the suppressive effect of Zhongtian hawthorn ethanol extract on the transcription of HMGCR via nuclear factor-kappa B (NF-κB) signal pathway. Therefore, this novel cultivar of hawthorn cultivar which has much bigger fruits, early bearing, high yield, cold resistance, and drought resistance, might be considered as a good alternative to Shan-Zha and has great value in the food and medicine industry. In addition, to our best knowledge, this is also the first report that the extract of Crataegus could suppress the transcription of HMGCR via NF-κB signal pathway. © 2016 by the Society for Experimental Biology and Medicine.

Ethanol extract of Zhongtian hawthorn lowers serum cholesterol in mice by inhibiting transcription of 3-hydroxy-3-methylglutaryl-CoA reductase via nuclear factor-kappa B signal pathway

PubMed Central

Hu, Hai-Jie; Dong, Qing-Qing; Mu, Ai; Shi, Guo-Long; Wang, Qiu-Tong; Chen, Xiao-Ying; Zhou, Hao; Zhang, Tong-Cun

2016-01-01

Hawthorn is a berry-like fruit from the species of Crataegus. In China, it has another more famous name, Shan-Zha, which has been used to improve digestion as a traditional Chinese medicine or food for thousands of years. Moreover, during the last decades, hawthorn has received more attention because of its potential to treat cardiovascular diseases. However, currently, only fruits of C. pinnatifida and C. pinnatifida var. major are included as Shan-Zha in the Chinese Pharmacopoeia. In this study, our results showed that the ethanol extract of Zhongtian hawthorn, a novel grafted cultivar of C. cuneata (wild Shan-Zha), could markedly reduce body weight and levels of serum total cholesterol, triglyceride, low-density lipoprotein cholesterol, and liver cholesterol of hyperlipidemia mice. It could suppress the stimulation effect of high-fat diet on the transcription of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) and p65, and counteract the downregulation of CYP7A1 and LDLR. In addition, the results of luciferase reporter assay and Western blot showed that the transcriptional activity of HMGCR promoter was inhibited by Zhongtian hawthorn ethanol extract in a dose-dependent manner, while overexpression of p65 could reverse this transcriptional repression effect. These results suggested that Zhongtian hawthorn could provide health benefits by counteracting the high-fat diet-induced hypercholesteolemic and hyperlipidemic effects in vivo, and the mechanism underlying this event was mainly dependent on the suppressive effect of Zhongtian hawthorn ethanol extract on the transcription of HMGCR via nuclear factor-kappa B (NF-κB) signal pathway. Therefore, this novel cultivar of hawthorn cultivar which has much bigger fruits, early bearing, high yield, cold resistance, and drought resistance, might be considered as a good alternative to Shan-Zha and has great value in the food and medicine industry. In addition, to our best knowledge, this is also the first report that the extract of Crataegus could suppress the transcription of HMGCR via NF-κB signal pathway. PMID:26825354

Ground Based Synoptic Instrumentation for Solar Observations (Postprint)

DTIC Science & Technology

2012-03-05

vector spectropolarimetry in FeI 630.15-630.25 nm wavelength range, and line-of-sight (circular) polarimetry in Fe I 6301.5-6302.5 Å, and Ca II 8542 Å...Stokes vector polarimetry . Opt. Eng. 38, 1402-1408, 1999. [22] C. U. Keller, J. W. Harvey, M. S. Giampapa, “SOLIS: an innovative suite of synoptic

An Examination of the Decision-Making Processes Used by Superintendents in Reducing School District Budgets

ERIC Educational Resources Information Center

Slaven, Lori A.

2014-01-01

Purpose: The purpose of this study was to determine the degree of importance of Harvey et al.'s (1997) 13 problem-solving strategies for making retrenchment decisions on school district budgets as perceived by California superintendents of medium-sized school districts. Methodology: The subjects in the present study were 86 superintendents of…

33 CFR 161.40 - Vessel Traffic Service Berwick Bay.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Waterway (ICW) Morgan City to Port Allen Alternate Route from Mile Marker 0 to Mile Marker 5; the ICW from Mile Marker 93 west of Harvey Lock (WHL) to Mile Marker 102 WHL; the Atchafalaya River Route from Mile Marker 113 to Mile Marker 122; from Bayou Shaffer Junction (ICW Mile Marker 94.5 WHL) south one statute...

33 CFR 161.40 - Vessel Traffic Service Berwick Bay.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Waterway (ICW) Morgan City to Port Allen Alternate Route from Mile Marker 0 to Mile Marker 5; the ICW from Mile Marker 93 west of Harvey Lock (WHL) to Mile Marker 102 WHL; the Atchafalaya River Route from Mile Marker 113 to Mile Marker 122; from Bayou Shaffer Junction (ICW Mile Marker 94.5 WHL) south one statute...

33 CFR 161.40 - Vessel Traffic Service Berwick Bay.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Waterway (ICW) Morgan City to Port Allen Alternate Route from Mile Marker 0 to Mile Marker 5; the ICW from Mile Marker 93 west of Harvey Lock (WHL) to Mile Marker 102 WHL; the Atchafalaya River Route from Mile Marker 113 to Mile Marker 122; from Bayou Shaffer Junction (ICW Mile Marker 94.5 WHL) south one statute...

33 CFR 161.40 - Vessel Traffic Service Berwick Bay.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Waterway (ICW) Morgan City to Port Allen Alternate Route from Mile Marker 0 to Mile Marker 5; the ICW from Mile Marker 93 west of Harvey Lock (WHL) to Mile Marker 102 WHL; the Atchafalaya River Route from Mile Marker 113 to Mile Marker 122; from Bayou Shaffer Junction (ICW Mile Marker 94.5 WHL) south one statute...

78 FR 25273 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-30

... Peachtree Street NE., Atlanta, Georgia 30309: 1. Harvey Alan Sorkin, Palm Beach Gardens, Florida; to acquire at least 10 percent of the voting shares of Floridian Community Holdings, Inc., and thereby indirectly acquire voting shares of Floridian Community Bank, Inc., both of Davie, Florida. B. Federal...

Studies on Typhus and Spotted Fever.

DTIC Science & Technology

1981-02-01

Rocky Mountain spotted fever , DNA, homology, genome, lymphocytes, immunity...spotted fever group. Certain studies have suggested that R. canada may be able to cause a severe illness in man clinically similar to Rocky Mountain spotted fever (Z...the Conference and are also in press. 10. Paul Fiset, Charles L. Wisseman, Jr., A. Farhang-Azad, Harvey Fischman. Rocky Mountain Spotted Fever

Sex-Role Stereotypes in Secondary School Theatre.

ERIC Educational Resources Information Center

Nalley, Sara

The five plays most frequently produced in high schools--"Our Town,""Harvey,""Arsenic and Old Lace,""You Can't Take It with You," and "The Curious Savage"--perpetuate an image of women that is no longer tolerated in most educational materials. An analysis of these plays shows that they include many more male than female roles and that female…

Still Humble and Hopeful: Two More Recommendations on Welcoming First-Generation Poor and Working-Class Students to College

ERIC Educational Resources Information Center

Oldfield, Kenneth

2012-01-01

In 2007, "About Campus" published the author's article "Humble and Hopeful: Welcoming First-Generation Poor and Working-Class Students to College." It has been used as a handout in various student orientations, included as a chapter in Teresa Heinz Housel and Vickie Harvey's "The Invisibility Factor: Administrators and…

76 FR 2117 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-12

........... 20090527........ G Andrew Gumaer 18-JUN-09........ 20090527........ G Great American Group, LLC 18-JUN-09... Harvey M. Yellen 18-JUN-09........ 20090528........ G Great American Group, LLC 19-JUN-09... Telecom Group, Inc. 26-JUN-09........ 20090537........ G FiberNet Telecom Group, Inc. 26-JUN-09...

Wallace Stevens: A Collection of Critical Essays. Twentieth Century Views Series.

ERIC Educational Resources Information Center

Borroff, Marie, Ed.

One of a series of works aimed at presenting contemporary critical opinion on major authors, this collection includes essays by Marie Borroff, Wallace Stevens, Joseph N. Riddle, Hi Simons, Sister M. Bernetta Quinn, C. Roland Wagner, Harold Bloom, Ralph J. Mills, Jr., Roy Harvey Pearce, Louis L. Martz, Morton Dauwen Zabel, and Northrop Frye--all…

75 FR 22864 - In the Matter of CAN USA, Inc., Harvey, Louisiana; General License Pursuant to 10 CFR 150.20...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-30

... response to the NRC's offer, CAN USA requested use of the NRC ADR process to resolve issues associated with... apparent violations, which include: (1) Providing additional training to radiographers, assistant... radiographic operations as customer transport allowed; and (5) Providing more ``real-time'' notifications of...

Silence in the Classroom: Some Thoughts about Teaching in the 1980s.

ERIC Educational Resources Information Center

Gimenez, Martha E.

1989-01-01

Discusses using the critical perspective as a methodology to teach a college sociology course. Examines the failure of this approach and looks at the determinants of student apathy. Concludes that failure is unavoidable, given the structure of higher education and the intellectual level of most students. Harvey Holtz and Richard A. Wright respond…

ARC-1957-A-23438

NASA Image and Video Library

1957-12-30

H. Julian 'Harvey' Allen in front of the NASA Ames 8_x_7 foot Supersonic Wind Tunnel test section. A blunt body model mounted in the test section is ready for testing . The 8_X_7_foot is part of the Unitary Plan WInd Tunnel Complex Note: printed in 60 year at NASA Ames Research Center by Glenn Bugos NASA SP-2000-4314

Wilderness restoration: From philosophical questions about naturalness to tests of practical techniques

Treesearch

David N. Cole

2008-01-01

When crafting the U.S. Wilderness Act, Howard Zahniser selected the word untrammeled rather than undisturbed to describe wilderness (Harvey 2005). This reflected his belief that places that had been disturbed by humans should be considered for wilderness designation because impaired ecosystems could be restored. Like many others, he hoped that restoration could be...

33 CFR 161.40 - Vessel Traffic Service Berwick Bay.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Waterway (ICW) Morgan City to Port Allen Alternate Route from Mile Marker 0 to Mile Marker 5; the ICW from Mile Marker 93 west of Harvey Lock (WHL) to Mile Marker 102 WHL; the Atchafalaya River Route from Mile... River. (b) VTS Special Area. The Berwick Bay VTS Special Area consists of those waters within a 1000...

78 FR 44133 - Cellular, Tissue and Gene Therapies Advisory Committee; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-23

... Dapolito or Rosanna Harvey, Food and Drug Administration, Center for Biologics Evaluation and Research... Research (CBER), FDA. On October 23, 2013, from 12:30 p.m. to approximately 5 p.m. the Committee will.... CBER is planning to publish guidance on this topic during calendar year 2013. FDA intends to make...

When the Exception Is the Rule: School Shootings, Bare Life, and the Sovereign Self

ERIC Educational Resources Information Center

Shapiro, Harvey

2015-01-01

Much discourse on school shootings tends to imply a binary separation between what is considered normal and exceptional, between an expected course of human events and sociohistorical aberrations. In this article Harvey Shapiro suggests the need for new directions in our responses: First, he shows how responses to school shootings tend to…

Cushing's Syndrome From Pituitary Microadenoma and Pulmonary Nodules.

PubMed

Tating, Dan Louie Renz P; Montevirgen, Natasha Denise S; Cajucom, Loyda

2016-03-01

Cushing's syndrome is a state of cortisol excess, possibly from a tumor in the pituitary gland, the adrenal gland, or an ectopic nonpituitary ACTH-secreting source. The first form, pituitary in origin, was originally described by Harvey Cushing, MD, and was labeled as Cushing's disease. Long-term therapy with glucocorticoids also can lead to iatrogenic Cushing's syndrome.

Knowledge, Belief, and Science Education: A Contribution from the Epistemology of Testimony

ERIC Educational Resources Information Center

Ferreira, Tiago Alfredo S.; El-Hani, Charbel N.; da Silva-Filho, Waldomiro José

2016-01-01

This article intends to show that the defense of "understanding" as one of the major goals of science education can be grounded on an anti-reductionist perspective on testimony as a source of knowledge. To do so, we critically revisit the discussion between Harvey Siegel and Alvin Goldman about the goals of science education, especially…

Simulation Training in Health Care

DTIC Science & Technology

2015-06-01

Harvey simulates cardiac and lung disease , including blood pressure, breathing, pulses, heart sounds, and murmurs. A significant step toward the...fluoroscopy, cardiovascu- lar and pulmonary disease diagnosis and treatment, anesthesia, patient -centered programs, basic vital signs emergency care, infant...effectiveness. However, in health care, ethical considerations and the quantification of the expenses of clinician “learning” on patients is a challenge to

75 FR 32275 - Regulated Navigation Area; Gulf Intracoastal Waterway, Inner Harbor Navigation Canal, Harvey...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-08

... period and may change the rule based on your comments. Viewing Comments and Documents To view comments... contingency plan be developed for vessels that are prevented from departing the Inner Harbor Navigation Canal... companies with adequate notice about the rule. The commenter also requested that the RNA be implemented as a...

A Class III Cultural Resource Inventory of a Portion of the Upper Souris River Valley, North Dakota

DTIC Science & Technology

1989-03-01

E. Sully led a force from Fort Rice , near present Bismarck, to Devils Lake and then to the Souris River. Sully skirted the bottom of the Souris loop...Manning (1923), Mabel Manning (1924), Alice Wakelam (1933), Harvey Emmel (1936), State Bank of Keninare (1937), State of North Dakota (1939), William

How Robert A. Millikan Got the Physics Nobel Prize

ERIC Educational Resources Information Center

Panusch, Martin; Heering, Peter; Singh, Rajinder

2010-01-01

In 1923, R.A. Millikan was awarded the Nobel Prize in Physics for his work on the elementary charge of electricity and on the photoelectric effect. Recently, historical research had a focus on Millikan's publication practice, as well as on the role of his assistant, Harvey Fletcher. Several studies have raised doubts on whether Millikan can…

33 CFR 165.838 - Regulated Navigation Area; Gulf Intracoastal Waterway, Inner Harbor Navigation Canal, New Orleans...

Code of Federal Regulations, 2014 CFR

2014-07-01

... before closure of the navigational structures, all floating vessels must depart the RNA except as follows... Harbor Navigation Canal, New Orleans, LA. (a) Location. The following is a regulated navigation area (RNA... West of Harvey Locks (WHL) (b) Definitions. As used in this section: (1) Breakaway means a floating...

How Does a Cowboy Make Money? Using Student Curiosities to Further Elementary School Inquiries

ERIC Educational Resources Information Center

Whitlock, Annie McMahon; Brugar, Kristy A.

2017-01-01

This article explores examples of student-initiated inquiries (in Grades 1 and 5) and the opportunities and challenges with engaging in them. To explore these student-initiated inquiries, we use the "C3 Framework" Inquiry Arc (National Council for the Social Studies, 2013) and Harvey and Daniels's (2009) Small-Group Inquiry Model to…

Metals in edible seaweed.

PubMed

Rubio, C; Napoleone, G; Luis-González, G; Gutiérrez, A J; González-Weller, D; Hardisson, A; Revert, C

2017-04-01

The concentration levels of 20 metals were analyzed by ICP-OES in edible seaweed (Chondrus, Eisenia, Gelidium, Himanthalia, Laminaria, Palmaria, Porphyra, Undaria), from two origins (Asia vs EU) according to their cultivation practices (conventional vs organic). Red seaweed showed higher concentrations of trace and toxic elements. Porphyra may be used as a potential bioindicator for metals. Significant differences were found between the Asian vs European mean contents. The mean Cd level from the conventional cultivation (0.28 mg/kg) was two points higher than the organic cultivation (0.13 mg/kg). A daily consumption of seaweed (4 g/day) contributes to the dietary intake of metals, mainly Mg and Cr. The average intakes of Al, Cd and Pb were 0.064, 0.001 and 0.0003 mg/day, respectively. Based on obtained results, this study suggests that exposure to the toxic metals analyzed (Al, Cd and Pb) through seaweed consumption does not raise serious health concerns, but other toxic metals should be monitored. Copyright © 2017. Published by Elsevier Ltd.

The Zapot pegmatite mineral county

USGS Publications Warehouse

Foord, E.E.; Soregaroli, A.E.; Gordon, H.M.

1999-01-01

The Zapot pegmatite is currently being mined for mineral specimens (chiefly amazonite, topaz and smoky quartz in miarolitic cavities), for gemstones (topaz and smoky quartz) and for decorative rock (amazonite). The deposit is owned and operated by Harvey Gordon Minerals of Reno, Nevada, and is the only amazonite-topaz mining operation in the state. Thousands of specimens from this operation have reached the collector market.

In Excess of Epistemology: Siegel, Taylor, Heidegger and the Conditions of Thought

ERIC Educational Resources Information Center

Williams, Emma

2015-01-01

Harvey Siegel's epistemologically-informed conception of critical thinking is one of the most influential accounts of critical thinking around today. In this article, I seek to open up an account of critical thinking that goes beyond the one defended by Siegel. I do this by re-reading an opposing view, which Siegel himself rejects as leaving…

Multi-Periodic Waves in Shallow Water

DTIC Science & Technology

1992-09-01

models-the Kadomtsev - Petviashvili (KP) equation . The KP equation describes the evolu- tion of weakly nonlinear, weakly two-dimensional waves on water of...experimentally. The analytical model is a family of periodic solutions of the Kadomtsev -Petviashuili equation . The experiments demonstrate the accuracy... Petviashvili Equation (with Norman Schef- fner & Harvey Segur). Proceedings, Nonlinear Water Waves Workshop, University of Bristol. England, 1991. Resonant

Where Have All the Robots Gone? Worker Dissatisfaction in the '70's.

ERIC Educational Resources Information Center

Sheppard, Harold L.; Herrick, Neal Q.

The book presents an overview of American worker dissatisfaction in the 1970's, based upon three separate national surveys taken among two groups: blue and white collar union member workers and the young American worker under 30 years of age. The text is preceded by a foreward by Harvey Swados, an authors' preface, and an introduction by Michael…

Learning from Lincoln: Leadership Practices for School Success

ERIC Educational Resources Information Center

Alvy, Harvey; Robbins, Pam

2010-01-01

When you think of great leaders, of course Abraham Lincoln would come to mind. But can the life of a great 19th century president really shed light on what 21st century school leaders should do? "Yes," say authors Harvey Alvy and Pam Robbins. Their book explores how Lincoln's ability to persevere and lead despite adversity provides a compelling…

Use of Spherical Nanoindentation to Characterize the Anisotropic Properties of Microscale Constituents and Interfaces in Hierarchically Structured Composite Materials

DTIC Science & Technology

2015-01-24

Lilleodden, P. Anderson, J.T. Wyrobek, Acta Materialia 44 (1996) 3585-3598. [75] W.W. Gerberich, S. Venkataraman , J. Nelson, H. Huang, E. Lilleodden, W...629-644. [76] W.W. Gerberich, S.K. Venkataraman , H. Huang, S.E. Harvey, D.L. Kohlstedt, Acta Metallurgica et Materialia 43 (1995) 1569. [77] A.E

"I Am Starving with No Hope to Survive": Southern African Perspectives on Pedagogies of Globalization

ERIC Educational Resources Information Center

Makoni, Sinfree; Makoni, Busi

2007-01-01

In this article, the authors briefly describe key issues central to what Spring (2007) refers to as the "industrial-consumer paradigm" and the role of English as the global language characterized by what Harvey (1990) called "time and space compression." The authors also comment and provide a critique of some of its primary…

76 FR 36314 - Safety Zone; Mile Marker 98.5 West of Harvey Lock Gulf Intracoastal Waterway to Mile Marker 108.5...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-22

..., levee system, vessels and tows from destruction, loss or injury due to hazards associated with rising... the general public, levee system, vessels and tows from the hazards associated with rising flood water... system, vessels and tows from destruction, loss or injury due to the hazards associated with rising flood...

Forensic Discrimination of 25 Isolates of Burkholderia mallei

DTIC Science & Technology

2007-10-01

Intraperitoneal Glanders ( Burkholderia mallei ). Vet. Pathol. 2000, 37, pp 626-636. 11. Neubauer, H.; Meyer, H.; Finke, E.-J. Human Glanders ...Agents of Melioidosis and Glanders , Burkholderia pseudomallei and Burkholderia mallei . J. Clin. Microbiol. 2003, 41(5), pp 2068-2079. 20. Srinivasan, A... BURKHOLDERIA MALLEI Steven P. Harvey RESEARCH AND TECHNOLOGY DIRECTORATE Jennifer M. Minter BATTELLE EASTERN SCIENCE AND TECHNOLOGY CENTER Aberdeen, MD

77 FR 35367 - Silt Water Conservancy District; Notice of Application Accepted for Filing and Soliciting...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-13

... Harvey Gap 400 Project would be located on the existing Grass Valley Canal irrigation pipeline in... will be located. g. Filed Pursuant to: Federal Power Act 16 U.S.C. 791a-825r. h. Applicant Contacts... address in item h above. n. Development Application--Any qualified applicant desiring to file a competing...

The Literacy Myth Continues: Adapting Graff's Thesis to Contemporary Policy Discourses on Adult "Foundation Skills" in Australia

ERIC Educational Resources Information Center

Black, Stephen; Yasukawa, Keiko

2014-01-01

Harvey Graff in his 1979 study of literacy taught in common schools in mid-nineteenth century Canada, demonstrated that beliefs in the acquisition of literacy for upward mobility and economic success were a myth. Moreover, literacy instruction was promoted by educational reformers and manufacturers as a means of controlling the working class…

Looking toward the Future: A Case Study of Open Source Software in the Humanities

ERIC Educational Resources Information Center

Quamen, Harvey

2006-01-01

In this article Harvey Quamen examines how the philosophy of open source software might be of particular benefit to humanities scholars in the near future--particularly for academic journals with limited financial resources. To this end he provides a case study in which he describes his use of open source technology (MySQL database software and…

Impact of GPM Rainrate Data Assimilation on Simulation of Hurricane Harvey (2017)

NASA Technical Reports Server (NTRS)

Li, Xuanli; Srikishen, Jayanthi; Zavodsky, Bradley; Mecikalski, John

2018-01-01

Built upon Tropical Rainfall Measuring Mission (TRMM) legacy for next-generation global observation of rain and snow. The GPM was launched in February 2014 with Dual-frequency Precipitation Radar (DPR) and GPM Microwave Imager (GMI) onboard. The GPM has a broad global coverage approximately 70deg S -70deg N with a swath of 245/125-km for the Ka (35.5 GHz)/Ku (13.6 GHz) band radar, and 850-km for the 13-channel GMI. GPM also features better retrievals for heavy, moderate, and light rain and snowfall To develop methodology to assimilate GPM surface precipitation data with Grid-point Statistical Interpolation (GSI) data assimilation system and WRF ARW model To investigate the potential and the value of utilizing GPM observation into NWP for operational environment The GPM rain rate data has been successfully assimilated using the GSI rain data assimilation package. Impacts of rain rate data have been found in temperature and moisture fields of initial conditions. 2.Assimilation of either GPM IMERG or GPROF rain product produces significant improvement in precipitation amount and structure for Hurricane Harvey (2017) forecast. Since IMERG data is available half-hourly, further forecast improvement is expected with continuous assimilation of IMERG data

A Brain Membrane Protein Similar to the Rat src Gene Product

NASA Astrophysics Data System (ADS)

Scheinberg, David A.; Strand, Mette

1981-01-01

We report the purification to homogeneity of a 20,000-dalton, transformation-related, rat cell membrane protein. This protein, p20, was originally identified in preparations of a defective woolly monkey leukemia virus pseudotype of Kirsten sarcoma virus. The chromatographically purified p20 was an acidic hydrophobic protein, capable of specifically binding GTP (dissociation constant = 15 μ M). This nucleotide binding property and other previously reported characteristics were similar to properties ascribed to the Harvey sarcoma virus src gene product. p20 also appeared similar to this src gene product when immunoprecipitates of both proteins were directly compared by one- and two-dimensional NaDodSO4 gel electrophoreses. However, the proteins were not identical, because their tryptic maps differed. Using a competition radioimmunoassay, we have measured the concentration of p20 in cells, viruses, and rat tissues: p20 was not encoded by rat sarcoma viruses because it was increased only slightly after Kirsten sarcoma virus transformation of rat cells and was not increased in nonrat cells transformed by the Kirsten or Harvey sarcoma virus. Remarkably, of 10 rat tissues examined, p20 was found predominantly in brain, specifically in the membranes.

Protective effect of 3,4-dihydroxybenzoic acid isolated from Cladophora wrightiana Harvey against ultraviolet B radiation-induced cell damage in human HaCaT keratinocytes.

PubMed

Cha, Ji Won; Piao, Mei Jing; Kim, Ki Cheon; Zheng, Jian; Yao, Cheng Wen; Hyun, Chang Lim; Kang, Hee Kyoung; Yoo, Eun Sook; Koh, Young Sang; Lee, Nam Ho; Ko, Mi Hee; Hyun, Jin Won

2014-03-01

The aim of the present study was to elucidate the protective properties of 3,4-dihydroxybenzoic acid (DBA) isolated from Cladophora wrightiana Harvey (a green alga) against ultraviolet B (UVB)-induced damage to human HaCaT keratinocytes. DBA exhibited scavenging actions against the 1,1-diphenyl-2-picrylhydrazyl radical, the superoxide anion, and the hydroxyl radical. Furthermore, DBA decreased the levels of intracellular reactive oxygen species generated by hydrogen peroxide or UVB treatment of the cells. DBA also decreased the UVB-augmented levels of phospho-histone H2A.X and the extent of comet tail formation, which are both indications of DNA damage. In addition, the compound safeguarded keratinocytes from UVB-induced injury by reversing the production of apoptotic bodies, overturning the disruption of mitochondrial membrane potential, increasing the expression of the anti-apoptotic protein, B-cell lymphoma 2, and decreasing the expression of the pro-apoptotic proteins, Bcl-2-associated X and cleaved caspase-3. Taken together, these results demonstrate that DBA isolated from a green alga protects human keratinocytes against UVB-induced oxidative stress and apoptosis.

Structural analysis of proanthocyanidins isolated from fruit stone of Chinese hawthorn with potent antityrosinase and antioxidant activity.

PubMed

Chai, Wei-Ming; Chen, Chih-Min; Gao, Yu-Sen; Feng, Hui-Ling; Ding, Yu-Mei; Shi, Yan; Zhou, Han-Tao; Chen, Qing-Xi

2014-01-08

Proanthocyanidins were isolated from fruit stone of Chinese hawthorn (Crataegus pinnatifida Bge. var. major N.E.Br.). Their structures were analyzed and elucidated by methods of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and high performance liquid chromatography electrospray ionization mass spectrometry (HPLC-ESI-MS). The results demonstrated that these compounds are complicated mixtures of homo- and heteropolymers consisting of procyanidin/procyanidin gallate and prodelphinidin. They possessed structural heterogeneity in monomer units, polymer length, and interflavan linkage (A-type and B-type). Their antityrosinase and antioxidant activity were then investigated. The results revealed that they can inhibit tyrosinase activities, including the monophenolase activity and the diphenolase activity. In addition, proanthocyanidins possessed potent antioxidant activity. Our studies revealed that proanthocyanidins isolated from fruit stone of Chinese hawthorn may be applied in food, agriculture, pharmaceutical, and cosmetic industries.

Factor Structure of the Acute Stress Disorder Scale in a Sample of Hurricane Katrina Evacuees

ERIC Educational Resources Information Center

Edmondson, Donald; Mills, Mary Alice; Park, Crystal L.

2010-01-01

Acute stress disorder (ASD) is a poorly understood and controversial diagnosis (A. G. Harvey & R. A. Bryant, 2002). The present study used confirmatory factor analysis (CFA) to test the factor structure of the most widely used self-report measure of ASD, the Acute Stress Disorder Scale (R. A. Bryant, M. L. Moulds, & R. M. Guthrie, 2000),…

Geophysical Plasmas and Atmospheric Modeling.

DTIC Science & Technology

1985-03-01

Supriya Ganguli, Charles Goodrich, Adil Hassam, Y.C. Lee, Horace Mitchell, Dennis Papadopoulos, Harvey Rowland, Keith Sashegyi, Punyamurthula...Mesosphere and Lower Thermosphere" which is being prepared for publication in J. Geophys. Res. with John U P. Apruzese (NRL) and Mark R. Schoeberl (Goddard...and G.F. Pinder, Numerical Solution of Partial Differential Equations in Science and Engineering, John Wiley & Sons, New ;York, 1982. 18. See, for

The Role of Scale and Model Bias in ADAPT's Photospheric Eatimation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Godinez Vazquez, Humberto C.; Hickmann, Kyle Scott; Arge, Charles Nicholas

2015-05-20

The Air Force Assimilative Photospheric flux Transport model (ADAPT), is a magnetic flux propagation based on Worden-Harvey (WH) model. ADAPT would be used to provide a global photospheric map of the Earth. A data assimilation method based on the Ensemble Kalman Filter (EnKF), a method of Monte Carlo approximation tied with Kalman filtering, is used in calculating the ADAPT models.

The Mission Partner Environment: Challenges To Multinational Information Sharing

DTIC Science & Technology

2016-02-15

Harvey , Royal Air Force 15 February 2016 DISTRIBUTION A. Approved for public release: distribution unlimited. ii Disclaimer The views expressed...troops, with non-U.S. commanders in charge of vast areas of inhospitable geography . The enormous size and scope of this mission created incredibly...between people and organizations separated by wide geography is the requirement for a persistent and durable means for multinational communication and

33 CFR 89.27 - Waters upon which Inland Rule 24(i) applies.

Code of Federal Regulations, 2012 CFR

2012-07-01

...), while transiting within the following areas: (1) St. Andrews Bay from the Hathaway Fixed Bridge at Mile 284.6 East of Harvey Locks (EHL) to the DuPont Fixed Bridge at Mile 295.4 EHL. (2) Pensacola Bay, Santa Rosa Sound and Big Lagoon from the Light “10” off of Trout Point at Mile 176.9 EHL to the...

33 CFR 89.27 - Waters upon which Inland Rule 24(i) applies.

Code of Federal Regulations, 2013 CFR

2013-07-01

...), while transiting within the following areas: (1) St. Andrews Bay from the Hathaway Fixed Bridge at Mile 284.6 East of Harvey Locks (EHL) to the DuPont Fixed Bridge at Mile 295.4 EHL. (2) Pensacola Bay, Santa Rosa Sound and Big Lagoon from the Light “10” off of Trout Point at Mile 176.9 EHL to the...

33 CFR 89.27 - Waters upon which Inland Rule 24(i) applies.

Code of Federal Regulations, 2014 CFR

2014-07-01

...), while transiting within the following areas: (1) St. Andrews Bay from the Hathaway Fixed Bridge at Mile 284.6 East of Harvey Locks (EHL) to the DuPont Fixed Bridge at Mile 295.4 EHL. (2) Pensacola Bay, Santa Rosa Sound and Big Lagoon from the Light “10” off of Trout Point at Mile 176.9 EHL to the...

33 CFR 89.27 - Waters upon which Inland Rule 24(i) applies.

Code of Federal Regulations, 2011 CFR

2011-07-01

...), while transiting within the following areas: (1) St. Andrews Bay from the Hathaway Fixed Bridge at Mile 284.6 East of Harvey Locks (EHL) to the DuPont Fixed Bridge at Mile 295.4 EHL. (2) Pensacola Bay, Santa Rosa Sound and Big Lagoon from the Light “10” off of Trout Point at Mile 176.9 EHL to the...

33 CFR 207.187 - Gulf Intracoastal Waterway, Tex.; special floodgate, lock and navigation regulations.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Colorado River Locks at Mile 400.8 and Mile 441.5, respectively, west of Harvey Lock, La., on the Gulf...) Unlimited passage. The floodgates and locks shall be opened for the passage of single vessels and towboats with single or multiple barges when the current in the river is less than 2 miles per hour and the head...

33 CFR 207.187 - Gulf Intracoastal Waterway, Tex.; special floodgate, lock and navigation regulations.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Colorado River Locks at Mile 400.8 and Mile 441.5, respectively, west of Harvey Lock, La., on the Gulf...) Unlimited passage. The floodgates and locks shall be opened for the passage of single vessels and towboats with single or multiple barges when the current in the river is less than 2 miles per hour and the head...

Improving Music Experiences for Emotionally Handicapped Children in Public School Programs. Proceedings of a Special Study Institute (Rochester, New York, October 23-25, 1969).

ERIC Educational Resources Information Center

New York State Education Dept., Albany.

Included in the proceedings of the study institute on Improving Music Experiences for Emotionally Handicapped Children in Public School Programs are statements of greeting (Charles Matkowski, Harvey Granite), an overview by Donald Hayden, and the key note address by Mrs. Theresa Goodell. From the second session are included statements from three…

A Financial Approach as an Alternative Organizational Development Intervention.

DTIC Science & Technology

1979-12-01

Participants: (age group) (#Available) (# Program (#confirmed/ designed for) reserved) Program requested by: Board of Directors PSO Staff Community...Milestone chart approved by: on ’ name date 59 APPENDIX F PSO PROGRAM WORKSHEET INSTRUCTIONS Purpose: The Program Worksheet is designed to collect all inform...11. Grossman, Lee, The Change Agent, Amacom, New York, 1974. 12. Harvey, Donald F., and Brown, Donald R., An Eperimental Approach to Organization

Traffic Control Measures for Crisis Relocation.

DTIC Science & Technology

1983-01-01

fair in life-threatening circumstances, and consequently, may not be widely observed. Such rules, moreover, provide grist for the mill of the cassandras ...English and Mary Clare Harvey, Derailment, The Mississauga Miraci, Mississauga, Ontario, Canada. 2. Burrows, Douglas K., Emergencv Evacuation of the City...1974. 6. Havey, Mary Clare , et al., Derailmentt The Mississauga Miracle, Province of Ontario, November 1980. 7. Scanlon, Joseph, The Peel Regional

Behavioral Studies on the Mechanism of Buspirone, an Atypical Anti-Anxiety Drug

DTIC Science & Technology

1986-06-17

D. P., Hyslop , D. K., & Riblet, L. AA Buspirone: A model for anxioselective drug action. Neuroscie~ce 8bstracts, 1980 , ~, 791. Temple, D. L...shows few other similarites to conventional anxiolytics. While benzodiazepines (BZs) are potent anticonvulsants and sedatives (Harvey, 1980 ), buspirone...anxiolytics, and is considered an effective predictor of their effectiveness (Sepinwall & Cook, 1980 ). However, compounds that stimulate GABA receptors

Draft Genome Sequence of the Nicotinate-Metabolizing Soil Bacterium Bacillus niacini DSM 2923.

PubMed

Harvey, Zachary H; Snider, Mark J

2014-12-04

Bacillus niacini is a member of a small yet diverse group of bacteria able to catabolize nicotinic acid. We report here the availability of a draft genome for B. niacini, which we will use to understand the evolution of its namesake phenotype, which appears to be unique among the species in its phylogenetic neighborhood. Copyright © 2014 Harvey and Snider.

Mortuary Affairs Soldiers: Early Intervention and Altering Barriers to Care for Traumatic Stress and PTSD

DTIC Science & Technology

2014-11-01

military populations and have implications for interventions with disaster workers and others exposed to the dead. Keywords US Army, soldier... military deployment can be high (Cigrang et al., 2014; Hoge et al., 2004; Prigerson, Maciejewski & Rosenheck, 2002; Ursano & Norwood, 1996...have documented the psychological effects of working with human remains on military personnel and disaster workers (Bryant & Harvey, 1996; Clohessy

77 FR 35369 - Silt Water Conservancy District; Notice of Application Accepted for Filing and Soliciting...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-13

... Harvey Gap 50 Project would be located on the existing Grass Valley Canal in Garfield County, Colorado... Pursuant to: Federal Power Act 16 U.S.C. 791a-825r. h. Applicant Contacts: Dan Cokley, Schmueser Gordon... (202) 502-8659. A copy is also available for review and reproduction at the address in item h above. n...

Management implications of recent changes in spatial patterns of interior northwest forests.

Treesearch

Paul. F. Hessburg; Bradley G. Smith

1999-01-01

Declining health of forest ecosystems in the interior West has been the subject of much study, concern and controversy in recent years (e.g., Everett et al. 1994, Harvey et al. 1995, Lehmkuhl et al. 1994, O'Laughlin et al. 1993, Wickman 1992). Land-use practices of this century have altered disturbance regimes and spatial and temporal patterns of vegetation, and...

Debating International Learner Assessments as a Proxy Measure of Quality of Education in the Context of EFA--A Review Essay

ERIC Educational Resources Information Center

Mulongo, Godfrey

2014-01-01

This review essay looks at three publications that discuss the contentious issue of evaluating education quality (Note 1) by learner outcomes as a proxy indicator (Note 2). The essay explores the debates, gaps and proposes recommendations in the context of Education For All (EFA) (Note 3). The three articles reviewed are Harvey Goldstein's (2004)…

Collaborative, Rapid Mapping of Water Extents During Hurricane Harvey Using Optical and Radar Satellite Sensors

NASA Astrophysics Data System (ADS)

Muench, R.; Jones, M.; Herndon, K. E.; Bell, J. R.; Anderson, E. R.; Markert, K. N.; Molthan, A.; Adams, E. C.; Shultz, L.; Cherrington, E. A.; Flores, A.; Lucey, R.; Munroe, T.; Layne, G.; Pulla, S. T.; Weigel, A. M.; Tondapu, G.

2017-12-01

On August 25, 2017, Hurricane Harvey made landfall between Port Aransas and Port O'Connor, Texas, bringing with it unprecedented amounts of rainfall and flooding. In times of natural disasters of this nature, emergency responders require timely and accurate information about the hazard in order to assess and plan for disaster response. Due to the extreme flooding impacts associated with Hurricane Harvey, delineations of water extent were crucial to inform resource deployment. Through the USGS's Hazards Data Distribution System, government and commercial vendors were able to acquire and distribute various satellite imagery to analysts to create value-added products that can be used by these emergency responders. Rapid-response water extent maps were created through a collaborative multi-organization and multi-sensor approach. One team of researchers created Synthetic Aperture Radar (SAR) water extent maps using modified Copernicus Sentinel data (2017), processed by ESA. This group used backscatter images, pre-processed by the Alaska Satellite Facility's Hybrid Pluggable Processing Pipeline (HyP3), to identify and apply a threshold to identify water in the image. Quality control was conducted by manually examining the image and correcting for potential errors. Another group of researchers and graduate student volunteers derived water masks from high resolution DigitalGlobe and SPOT images. Through a system of standardized image processing, quality control measures, and communication channels the team provided timely and fairly accurate water extent maps to support a larger NASA Disasters Program response. The optical imagery was processed through a combination of various band thresholds by using Normalized Difference Water Index (NDWI), Modified Normalized Water Index (MNDWI), Normalized Difference Vegetation Index (NDVI), and cloud masking. Several aspects of the pre-processing and image access were run on internal servers to expedite the provision of images to analysts who could focus on manipulating thresholds and quality control checks for maximum accuracy within the time constraints. The combined results of the radar- and optical-derived value-added products through the coordination of multiple organizations provided timely information for emergency response and recovery efforts

Collaborative, Rapid Mapping of Water Extents During Hurricane Harvey Using Optical and Radar Satellite Sensors

NASA Technical Reports Server (NTRS)

Muench, Rebekke; Jones, Madeline; Herndon, Kelsey; Schultz, Lori; Bell, Jordan; Anderson, Eric; Markert, Kel; Molthan, Andrew; Adams, Emily; Cherrington, Emil;

Hurricane Harvey: Infrastructure Damage Assessment of Texas' Central Gulf Coast Region

NASA Astrophysics Data System (ADS)

Mooney, W. D.; Fovenyessy, S.; Patterson, S. F.

2017-12-01

We report a detailed ground-based damage survey for Hurricane Harvey, the first major hurricane to make landfall along the central Texas coast since the 1970 Category 3 Hurricane Celia. Harvey, a Category 4 storm, made landfall near Rockport, Texas on August 25th, 2017 at 10 PM local time. From September 2nd to 5th we visited Rockport and 22 nearby cities to assess the severity of the damage. Nearly all damage observed occurred as a direct result of the hurricane-force winds, rather than a storm surge. This observation is in contrast to the severe damage caused by both high winds and a significant storm surge, locally 3 to 5 m in height, in the 2013 Category 5 Hurricane Haiyan, that devastated the Philippines. We have adopted a damage scale and have given an average damage score for each of the areas investigated. Our damage contour map illustrates the areal variation in damage. The damage observed was widespread with a high degree of variability. Different types of damage included: (1) fallen fences and utility poles; (2) trees with branches broken or completely snapped in half; (3) business signs that were either partially or fully destroyed; (4) partially sunken or otherwise damaged boats; (5) and sheet metal sheds either completely or partially destroyed. There was also varying degrees of damage to both residential and commercial structures. Many homes had (6) roof damage, ranging from minor damage to complete destruction of the roof and second story, and (7) siding damage, where parts or whole sections of the homes siding had been removed. The area that had the lowest average damage score was Corpus Christi, and the areas that had the highest average damage score was both Fulton and Holiday Beach. There is no simple, uniform pattern of damage distribution. Rather, the damage was scattered, revealing hot spots of areas that received more damage than the surrounding area. However, when compared to the NOAA wind swath map, all of the damage was contained within the zone of highest wind speed.

Massey Award Given to Harvey Tananbaum

NASA Astrophysics Data System (ADS)

2010-06-01

Dr. Harvey Tananbaum, director of the Chandra X-ray Center, has been selected as the recipient of the 2010 Massey Award for his career accomplishments in high-energy astrophysics in space. The Massey Award is given by the Royal Society of London and the Committee of Space Research (COSPAR) in memory of Sir Harrie Massey, past Physical Secretary of the Society and member of the COSPAR Bureau. The prestigious award recognizes outstanding contributions to the development of space research in which a leadership role is of particular importance. Dr. Harvey Tananbaum began his career at American Science and Engineering and has been an astrophysicist at the Smithsonian Astrophysical Observatory since 1973. He was involved with pioneering X-ray astronomy missions including UHURU and the Einstein Observatory. Beginning in 1976, Dr. Tananbaum, along with Nobel Prize winner Dr. Riccardo Giacconi, led the team that proposed to NASA to study and design a large X-ray telescope. This project was launched 23 years later in 1999 as the Chandra X-ray Observatory, becoming NASA's flagship X-ray telescope. Dr. Tananbaum has served as the director of the Chandra X-ray Center since 1991. Dr. Tananbaum has received numerous awards from NASA as well as from other agencies and institutions, including the American Astronomical Society's Bruno Rossi Award in 2004 along with Chandra Project Scientist Martin Weisskopf. He is a fellow of the American Association for the Advancement of Science, and in 2005 was elected as a member of the United States National Academy of Science. The presentation of the Massey Award, along with the gold medal that accompanies it, will be made at the upcoming 2010 COSPAR meeting in Bremen, Germany in July. NASA's Marshall Space Flight Center in Huntsville, Ala., manages the Chandra program for NASA's Science Mission Directorate in Washington. The Smithsonian Astrophysical Observatory controls Chandra's science and flight operations from Cambridge, Mass. A complete list of previous award recipients may be found at: http://cosparhq.cnes.fr/Awards/awards.htm More information on Chandra can be found at: http://chandra.harvard.edu and http://chandra.nasa.gov

Inundation and draining of the Trinity River floodplain associated with extreme precipitation from Hurricane Harvey, east Texas, USA

NASA Astrophysics Data System (ADS)

Hassenruck-Gudipati, H. J.; Goudge, T. A.; Mohrig, D. C.

2017-12-01

Rivers swelled up beyond their historic high-water marks due to precipitation from Hurricane Harvey. We used Harvey-induced flooding to investigate the flow connectivity between the coastal Trinity River and its floodplain by measuring water depth and velocity, as well as sediment-transporting conditions on the natural levee that separates the two. River discharge within the study area peaked at a historic high of 3600 cubic meters per second on September 1, 2017. The levees on two river bends were investigated on September 3 and 4 in order to characterize the hydraulic connectivity between the channel and its floodplain during the early falling limb of this flood. On September 3, a river bend located approximately 28km upstream of the river mouth was visited. Water was overtopping the levee crest at this location, 30m away from the levee crest. This overland flow only experienced about a threefold reduction in average velocity to 0.16 m/s (in 2.2 m of water) 600m away from the levee crest. On September 4, a river bend approximately 59km upstream of the river mouth was investigated. Even though the river stage was at the National Weather Service major flood stage, the levee crest separating the river and floodplain was emergent. Regardless of this local disconnect between the river and its floodplain, substantial and variable drainage velocities were measured depending on drainage patterns controlled by local topography. Velocities measured in shallow water immediately adjacent to the emergent levee were low (< 0.05 m/s in 0.2 m of water). The highest drainage velocity ( 0.18 m/s in 1.7 m of water) associated with the upstream river-bend was measured at 750m from the channel and was similar in magnitude to those recorded for the distal inundating overland flow a day before on the downstream river-bend. Results from this work highlight the maintenance of high flow velocities across the distal floodplain even during its drainage phase. The transport of sediment, detrital organics, and solutes will be explored within the context of these overland flow velocities.

Managing the Chaos of Financial Management

DTIC Science & Technology

1995-05-01

Harvey Jones Mr. Wayne Thurman Lt Col Lawton Duncan Maj Michael Reardon, Maj Russell Vogel May 1995 19970814 026 ÜEIC QUALITY BJSPECTBD 8’ New...System (PC FuelsY 1 Oct 1993, 1. 59 Jamie Manker, "Aviation, Petroleum, Oil and Lubricant Funding decentralization—Too Much, Too Soon?" (Comptroller...Leedy, PaulD. Practical Research Planning and Design. New York: MacMillan Publishing Company, 1993. Manker, Jamie . "Aviation, Petroleum, Oil and

Stable SU(5) monopoles with higher magnetic charge

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miyamoto, S.; Sato, H.; Tomohiro, S.

1985-09-15

Taking into account the electroweak breaking effects, some multiply charged monopoles were shown to be stable by Gardner and Harvey. We give the explicit Ansa$uml: tze for finite-energy, nonsingular solutions of these stable higher-strength monopoles with eg = 1,(3/2),3. We also give the general stability conditions and the detailed behavior of the interaction potentials between two monopoles which produce the stable higher-strength monopoles.

Transactions of The Army Conference on Applied Mathematics and Computing (5th) Held in West Point, New York on 15-18 June 1987

DTIC Science & Technology

1988-03-01

29 Statistical Machine Learning for the Cognitive Selection of Nonlinear Programming Algorithms in Engineering Design Optimization Toward...interpolation and Interpolation by Box Spline Surfaces Charles K. Chui, Harvey Diamond, Louise A. Raphael. 301 Knot Selection for Least Squares...West Virginia University, Morgantown, West Virginia; and Louise Raphael, National Science Foundation, Washington, DC Knot Selection for Least

Comparing Perceptions of Teamness between Adult, First- and Second-Generation Mexican American and All Other Students Enrolled in a Cohort-Based, Accelerated, Bachelor's Degree Program

ERIC Educational Resources Information Center

Lincoln, Tami

2010-01-01

Purpose: The purpose of this study was to determine if there is a difference in the perception of the degree of teamness, as measured by the Characteristics of Effective Teams Survey (Harvey & Drolet, 2004), interviews, and archival data, between adult first- and second-generation Mexican American students and adult non-first- and…

Looking Forward to the Year 2000: Public Policy and Philanthropy. Working Papers, Spring Research Forum (San Francisco, California, March 17-18, 1988).

ERIC Educational Resources Information Center

Independent Sector, Washington, DC.

Forty-six working papers for presentation at a research forum on public policy and philanthropy are presented. Thirteen sections include the following topics: (1) looking forward to the year 2000: public policy and philanthropy (e.g. "Rationales for Tax Exemption," by Harvey P. Dale); (2) shifting boundaries among the sectors (e.g. "The Shifting…

Concept Development for Future Domains: A New Method of Knowledge Elicitation

DTIC Science & Technology

2005-06-01

Procedure: U.S. Army Research Institute for the Behavioral and Social Sciences (ARI) examined methods to generate, refine, test , and validate new...generate, elaborate, refine, describe, test , and validate new Future Force concepts relating to doctrine, tactics, techniques, procedures, unit and team...System (Harvey, 1993), and the Job Element Method (Primoff & Eyde , 1988). Figure 1 provides a more comprehensive list of task analytic methods. Please see

Privatization of Military Family Housing

DTIC Science & Technology

1998-08-17

author and the Contract Law Department, U.S. Army Judge Advocate General’s School, Charlottesville, Virginia) 𔃺 Memorandum, Harvey J. Nathan, Deputy...Improvement of Military Housing; Applicability of the Federal Acquisition Regulation (5 March 1997) (copy on file with the author and the Contract Law Department...Attachment 1, page 1-2 (copy on file with the author and the Contract Law Department, U.S. Army Judge Advocate General’s School, Charlottesville

Data points used to generate figures 2 through 6 in manuscript submission.

EPA Pesticide Factsheets

Excel files containing raw data used to generate figures throughout manuscript.This dataset is associated with the following publication:Dean , T., D. Betancourt , J. Kim, L. Harvey, A. Evans, and B. Grace. Biological Responses of Raw 264.7 Macrophage Exposed to Two Strains of Stachybotrys chartarum Spores Grown on Four Different Wallboard Types. INHALATION TOXICOLOGY. Taylor & Francis, Inc., Philadelphia, PA, USA, 28(7): 303-307, (2016).

Measuring and building resilience after big storms: Lessons learned from Super-Storm Sandy for the Harvey, Irma, Jose, and Maria coasts

NASA Astrophysics Data System (ADS)

Murdoch, P. S.; Penn, K. M.; Taylor, S. M.; Subramanian, B.; Bennett, R.

2017-12-01

As we recover from recent large storms, we need information to support increased environmental and socio-economic resilience of the Nation's coasts. Defining baseline conditions, tracking effects of mitigation actions, and measuring the uncertainty of resilience to future disturbance are essential so that the best management practices can be determined. The US Dept. of the Interior invested over $787 million dollars in 2013 to understand and mitigate coastal storm vulnerabilities and enhance resilience of the Northeast coast following Super-Storm Sandy. Several lessons-learned from that investment have direct application to mitigation and restoration needs following Hurricanes Harvey, Irma, Jose and Maria. New models of inundation, overwash, and erosion, developed during the Sandy projects have already been applied to coastlines before and after these recent storms. Results from wetland, beach, back-bay, estuary, and built-environment projects improved models of inundation and erosion from surge and waves. Tests of nature-based infrastructure for mitigating coastal disturbance yielded new concepts for best-practices. Ecological and socio-economic measurements established for detecting disturbance and tracking recovery provide baseline data critical to early detection of vulnerabilities. The Sandy lessons and preliminary applications on the recent storms could help define best-resilience practices before more costly mitigation or restoration efforts are required.

Attribution of extreme rainfall from Hurricane Harvey, August 2017

NASA Astrophysics Data System (ADS)

van der Wiel, K.; van Oldenborgh, G. J.; Sebastian, A.; Singh, R.; Arrighi, J.; Otto, F. E. L.; Haustein, K.; Li, S.; Vecchi, G.; Cullen, H. M.

2017-12-01

During August 25-30, 2017, Hurricane Harvey stalled over Texas and caused extreme precipitation over Houston and the surrounding area, particularly on August 26-28. This resulted in extensive flooding with over 80 fatalities and large economic costs. Using observational datasets and high-resolution global climate model experiments we investigate the return period of this event and to what extent anthropogenic climate change influenced the likelihood and intensity of this type of events. The event definition for the attribution is set by the main impact, flooding in the city of Houston. Most rivers crested on August 28 or 29, driven by intensive rainfall on August 26-28. We therefore use the annual maximum of three-day average precipitation as the event definition. Station data (GHCN-D) and a gridded precipitation product (CPC unified analysis) are used to find the return period of the event and changes in the observed record. To attribute changes to anthropogenic climate change we use time-slice experiments from two high-resolution global climate models (EC-Earth 2.3 and GFDL HiFLOR, both integrated at approximately 25 km). A regional model (HadRM3P) was rejected because of unrealistic modelled extremes. Finally we put the attribution results in context, given local vulnerability and exposure.

Chondracanthus tenellus (Harvey) hommersand extract protects the human keratinocyte cell line by blocking free radicals and UVB radiation-induced cell damage.

PubMed

Piao, Mei Jing; Hyun, Yu Jae; Oh, Tae-Heon; Kang, Hee Kyoung; Yoo, Eun Sook; Koh, Young Sang; Lee, Nam Ho; Suh, In Soo; Hyun, Jin Won

2012-12-01

The aim of this study was to investigate the protective effects of the ethanol extract of the red algae Chondracanthus tenellus (Harvey) Hommersand (CTE) on cultured human keratinocyte cell line. The cellular protection conferred by CTE was evidenced by the ability of the extract to absorb ultraviolet B (UVB; 280-320 nm) and to scavenge the radical 1,1-diphenyl-2-picrylhydrazyl, as well as intracellular reactive oxygen species (ROS), induced by either hydrogen peroxide (H(2)O(2)) or UVB radiation. In addition, both superoxide anion generated by the xanthine/xanthine oxidase system and hydroxyl radical generated by the Fenton reaction (FeSO(4) + H(2)O(2)) were scavenged by CTE, as confirmed using electron spin resonance spectrometry. In the human keratinocyte cell line, CTE decreased the degree of injury resulting from UVB-induced oxidative stress to lipids, proteins, and DNA. CTE-treated cells also showed a reduction in UVB-induced apoptosis, as exemplified by fewer apoptotic bodies and less DNA fragmentation. Taken together, these results suggest that CTE confers protection on the human keratinocyte cell line against UVB-induced oxidative stress by absorbing UVB ray and scavenging ROS, thereby reducing injury to cellular constituents.

Harvey Cushing Treated the First Known Patient With Carney Complex.

PubMed

Tsay, Cynthia J; Stratakis, Constantine A; Faucz, Fabio Rueda; London, Edra; Stathopoulou, Chaido; Allgauer, Michael; Quezado, Martha; Dagradi, Terry; Spencer, Dennis D; Lodish, Maya

2017-10-01

Carney complex (CNC) is a syndrome characterized by hyperplasia of endocrine organs and may present with clinical features of Cushing syndrome and acromegaly due to functional adrenal and pituitary gland tumors. CNC has been linked to mutations in the regulatory subunit of protein kinase A type I-alpha ( PRKAR1A ) gene. Tissue samples were taken from the hypothalamus or thalamus or tumors of patients with pituitary adenomas seen and operated on by neurosurgeon Harvey Cushing between 1913 and 1932. Following DNA extraction, sequencing for genes of interest was attempted, including PRKAR1A , AIP , USP8 , GNAS1 , and GPR101 , to explore the possibility that these mutations associated with acromegaly, CNC, and Cushing syndrome have been conserved over time. We report a patient described by Dr. Cushing in 1914 with a clinical presentation and postmortem findings suggestive of CNC. Genetic sequencing of the hypothalamus and pituitary adenoma revealed a germline heterozygous p.Arg74His mutation in the PRKAR1A gene, a codon previously described as mutated in CNC, but with a novel amino acid change. This patient is, to our knowledge, the first molecularly confirmed individual with CNC. This case demonstrates the power of modern genetics in studying archived tissues and the importance of recording detailed clinical notes in the diagnosis of disease.

Emergency Response Imagery Related to Hurricanes Harvey, Irma, and Maria

NASA Astrophysics Data System (ADS)

Worthem, A. V.; Madore, B.; Imahori, G.; Woolard, J.; Sellars, J.; Halbach, A.; Helmricks, D.; Quarrick, J.

2017-12-01

NOAA's National Geodetic Survey (NGS) and Remote Sensing Division acquired and rapidly disseminated emergency response imagery related to the three recent hurricanes Harvey, Irma, and Maria. Aerial imagery was collected using a Trimble Digital Sensor System, a high-resolution digital camera, by means of NOAA's King Air 350ER and DeHavilland Twin Otter (DHC-6) Aircraft. The emergency response images are used to assess the before and after effects of the hurricanes' damage. The imagery aids emergency responders, such as FEMA, Coast Guard, and other state and local governments, in developing recovery strategies and efforts by prioritizing areas most affected and distributing appropriate resources. Collected imagery is also used to provide damage assessment for use in long-term recovery and rebuilding efforts. Additionally, the imagery allows for those evacuated persons to see images of their homes and neighborhoods remotely. Each of the individual images are processed through ortho-rectification and merged into a uniform mosaic image. These remotely sensed datasets are publically available, and often used by web-based map servers as well as, federal, state, and local government agencies. This poster will show the imagery collected for these three hurricanes and the processes involved in getting data quickly into the hands of those that need it most.

"Can't walk nor raise arms to head": Harvey Cushing's surgical treatment of poliomyelitis.

PubMed

Pendleton, Courtney; Dorsi, Michael J; Belzberg, Allan J; Cohen-Gadol, Aaron A; Quiñones-Hinojosa, Alfredo

2012-02-15

This study was a retrospective chart review for patients undergoing operative treatment by Dr. Harvey Cushing at the Johns Hopkins Hospital between 1896 and 1912. To illustrate the early use of peripheral nerve anastomoses for the treatment of postpoliomyelitis paralysis. At the turn of the 20th century, poliomyelitis was recognized as a disease of neurons; neurological surgeons sought to find a surgical cure for the paralysis occurring after the disease onset. Peripheral nerve anastomoses were an attractive option employed during this time. Following IRB approval, and through the courtesy of the Alan Mason Chesney Archives, the surgical records of the Johns Hopkins Hospital from 1896 to 1912 were reviewed. A single case of peripheral nerve anastomosis for the treatment of postpoliomyelitis paralysis was selected for further analysis. Cushing performed a multiple peripheral nerve anastomoses in a 3-year-old girl. Although the patient experienced no postoperative complications, there was no improvement in her function at the time of discharge from the hospital, and no long-term follow-up was available. While unsuccessful, Cushing's use of peripheral nerve anastomoses to restore motor function in the pediatric patient described here demonstrates his commitment to pushing the boundaries of neurological surgery at the turn of the 20th century.

Vascular access: an historical perspective from Sir William Harvey to the 1956 Nobel prize to André F. Cournand, Werner Forssmann, and Dickinson W. Richards.

PubMed

Sette, Piersandro; Dorizzi, Romolo M; Azzini, Anna M

2012-01-01

Sir William Harvey (1578-1657), who had many precursors, discovered blood circulation in 1628 after a significant number of anatomic dissection of cadavers; his studies were continued by Sir Christopher Wren and Daniel Johann Major. The first central vein catheterization was performed on a horse by Stephen Hales, an English Vicar. In 1844, a century later, the French biologist Claude Bernard attempted the first carotid artery cannulation and repeated the procedure in the jugular vein, again on a horse. He was first to report the complications now well known to be associated with this maneuver. In 1929 Werner Forssmann tried cardiac catheterization on himself, but could not investigate the procedure further since his findings were rejected and ridiculed by colleagues. His work was continued by André Frédéric Cournand and Dickinson Woodruff Richards Jr in the United States. In 1956 the three physicians shared the Nobel Prize for Medicine for their studies on vascular and cardiac systems. The genius and the perseverance of the three physicians paved the way towards peripheral and central catheter vein placement, one of the most frequently performed maneuvers in hospitals. Its history still remains unknown to most and deserves a short description.

Treatment of Crohn's disease with cannabis: an observational study.

PubMed

Naftali, Timna; Lev, Lihi Bar; Yablecovitch, Doron; Yablekovitz, Doron; Half, Elisabeth; Konikoff, Fred M

2011-08-01

The marijuana plant cannabis is known to have therapeutic effects, including improvement of inflammatory processes. However, no report of patients using cannabis for Crohn's disease (CD) was ever published. To describe the effects of cannabis use in patients suffering from CD. In this retrospective observational study we examined disease activity, use of medication, need for surgery, and hospitalization before and after cannabis use in 30 patients (26 males) with CD. Disease activity was assessed by the Harvey Bradshaw index for Crohn's disease. Of the 30 patients 21 improved significantly after treatment with cannabis. The average Harvey Bradshaw index improved from 14 +/- 6.7 to 7 +/- 4.7 (P < 0.001). The need for other medication was significantly reduced. Fifteen of the patients had 19 surgeries during an average period of 9 years before cannabis use, but only 2 required surgery during an average period of 3 years of cannabis use. This is the first report of cannabis use in Crohn's disease in humans. The results indicate that cannabis may have a positive effect on disease activity, as reflected by reduction in disease activity index and in the need for other drugs and surgery. Prospective placebo-controlled studies are warranted to fully evaluate the efficacy and side effects of cannabis in CD.

Arterial Stiffening in Perspective: Advances in Physical and Physiological Science Over Centuries.

PubMed

O'Rourke, Michael F; O'Brien, Caroline; Edelman, Elazer R

2016-07-01

Arterial stiffening is not a new issue in medicine or research but was the prime concern of Richard Bright in the early 19th century and of the prominent London physicians and pathologists who tried to unscramble the relationship between kidney, heart, and cerebrovascular disease and hardness of the pulse in the late 19th century. It was of major concern to medical educators including Osler and Mackenzie who were still active in practice 100 years ago. It is all too easy (when dependent on the Internet) to consider arterial stiffness to be a new issue. The terms arterial stiffness, aortic stiffness, or wave reflection do not appear as categories for articles such as this in respectable journals, nor in categories for meetings of specialized physicians. Yet as described in this article, the subject was of interest to clinicians, to investigators such as Harvey in the 17th century, and to physicists who developed laws and principles of elasticity from the study of biological materials including ligaments and arteries. This paper provides a perspective on arterial stiffness from the time of William Harvey and Isaac Newton to the present, with a glance into the future. © American Journal of Hypertension, Ltd 2016. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

The autopsy was conducted "Under most inauspicious circumstances:" John Turner, Harvey Cushing's case XXXII, and his unwitting contributions to the early understanding of acromegaly.

PubMed

Pendleton, Courtney; Wand, Gary; Quinones-Hinojosa, Alfredo

2010-12-01

Harvey Cushing's monograph The Pituitary Body and Its Disorders describes Case XXXII, a 36-year-old man who presented with gigantism in 1910. The detailed post-mortem exam findings are prefaced with a cryptic statement, describing "inauspicious circumstances" surrounding the autopsy. Although contemporary biographies of Cushing have offered insight into these circumstances, the original surgical file for Case XXXII has not been previously reviewed. The original Johns Hopkins Hospital surgical records were reviewed, and the case of John Turner, who Cushing identified by name in his monograph The Pituitary Body and Its Disorders, was selected for further review. A review of the original surgical file revealed a typewritten note by Dr. Crowe, one of the surgeons who performed the post-mortem exam, with a handwritten addendum by Dr. Cushing. This document provides detail regarding the "inauspicious circumstances" surrounding the autopsy. Namely, the autopsy was conducted without permission of the family, during the funeral service, following a payment to the undertaker. The new information regarding the autopsy of John Turner offers insight into the previously incompletely described circumstances surrounding the autopsy. Additionally, the case illuminates the obligations and ethical quandaries that physician-scientists face.

Information Systems Coordinate Emergency Management

NASA Technical Reports Server (NTRS)

2012-01-01

The rescue crews have been searching for the woman for nearly a week. Hurricane Katrina devastated Hancock County, the southernmost point in Mississippi, and the woman had stayed through the storm in her beach house. There is little hope of finding her alive; the search teams know she is gone because the house is gone. Late at night in the art classroom of the school that is serving as the county s emergency operations center, Craig Harvey is discussing the search with the center s commander. Harvey is the Chief Operating Officer of a unique company called NVision Solutions Inc., based at NASA s Stennis Space Center in Bay St. Louis, only a couple of miles away. He and his entire staff have set up a volunteer operation in the art room, supporting the emergency management efforts using technology and capabilities the company developed through its NASA partnerships. As he talks to the commander, Harvey feels an idea taking shape that might lead them to the woman s location. Working with surface elevation data and hydrological principles, Harvey creates a map showing how the floodwaters from the storm would have flowed along the topography of the region around the woman s former home. Using the map, search crews find the woman s body in 15 minutes. Recovering individuals who have been lost is a sad reality of emergency management in the wake of a disaster like Hurricane Katrina in 2005. But the sooner answers can be provided, the sooner a community s overall recovery can take place. When damage is extensive, resources are scattered, and people are in dire need of food, shelter, and medical assistance, the speed and efficiency of emergency operations can be the key to limiting the impact of a disaster and speeding the process of recovery. And a key to quick and effective emergency planning and response is geographic information. With a host of Earth-observing satellites orbiting the globe at all times, NASA generates an unmatched wealth of data about our ever-changing planet. This information can be captured, analyzed, and visualized by geographic information systems (GIS) to produce maps, charts, and other tools that can reveal information essential to a wide variety of applications including emergency management. Knowing precise, real-time information about the size, location, environmental conditions, and resulting damage of an event like a flood or wildfire as well as the location and numbers of emergency responders and other resources contributes directly to the effectiveness of disaster mitigation. The need for such information is also evident when responding to homeland security threats, such as a terrorist attack. Recognizing the value of its geospatial information resources for this and other purposes, in 1998 Stennis and the state of Mississippi partnered to form what became the Enterprise for Innovative Geospatial Solutions (EIGS) industry cluster, supporting the growth of remote sensing and GIS-based research and business. As part of EIGS, several companies partnered with NASA through dual use and Small Business Innovation Research (SBIR) contracts. Among those was NVision.

Biochar from commercially cultivated seaweed for soil amelioration

PubMed Central

Roberts, David A.; Paul, Nicholas A.; Dworjanyn, Symon A.; Bird, Michael I.; de Nys, Rocky

2015-01-01

Seaweed cultivation is a high growth industry that is primarily targeted at human food and hydrocolloid markets. However, seaweed biomass also offers a feedstock for the production of nutrient-rich biochar for soil amelioration. We provide the first data of biochar yield and characteristics from intensively cultivated seaweeds (Saccharina, Undaria and Sargassum – brown seaweeds, and Gracilaria, Kappaphycus and Eucheuma – red seaweeds). While there is some variability in biochar properties as a function of the origin of seaweed, there are several defining and consistent characteristics of seaweed biochar, in particular a relatively low C content and surface area but high yield, essential trace elements (N, P and K) and exchangeable cations (particularly K). The pH of seaweed biochar ranges from neutral (7) to alkaline (11), allowing for broad-spectrum applications in diverse soil types. We find that seaweed biochar is a unique material for soil amelioration that is consistently different to biochar derived from ligno-cellulosic feedstock. Blending of seaweed and ligno-cellulosic biochar could provide a soil ameliorant that combines a high fixed C content with a mineral-rich substrate to enhance crop productivity. PMID:25856799

Biochar from commercially cultivated seaweed for soil amelioration.

PubMed

Roberts, David A; Paul, Nicholas A; Dworjanyn, Symon A; Bird, Michael I; de Nys, Rocky

2015-04-09

Seaweed cultivation is a high growth industry that is primarily targeted at human food and hydrocolloid markets. However, seaweed biomass also offers a feedstock for the production of nutrient-rich biochar for soil amelioration. We provide the first data of biochar yield and characteristics from intensively cultivated seaweeds (Saccharina, Undaria and Sargassum--brown seaweeds, and Gracilaria, Kappaphycus and Eucheuma--red seaweeds). While there is some variability in biochar properties as a function of the origin of seaweed, there are several defining and consistent characteristics of seaweed biochar, in particular a relatively low C content and surface area but high yield, essential trace elements (N, P and K) and exchangeable cations (particularly K). The pH of seaweed biochar ranges from neutral (7) to alkaline (11), allowing for broad-spectrum applications in diverse soil types. We find that seaweed biochar is a unique material for soil amelioration that is consistently different to biochar derived from ligno-cellulosic feedstock. Blending of seaweed and ligno-cellulosic biochar could provide a soil ameliorant that combines a high fixed C content with a mineral-rich substrate to enhance crop productivity.

Biochar from commercially cultivated seaweed for soil amelioration

NASA Astrophysics Data System (ADS)

Roberts, David A.; Paul, Nicholas A.; Dworjanyn, Symon A.; Bird, Michael I.; de Nys, Rocky

2015-04-01

Seaweed cultivation is a high growth industry that is primarily targeted at human food and hydrocolloid markets. However, seaweed biomass also offers a feedstock for the production of nutrient-rich biochar for soil amelioration. We provide the first data of biochar yield and characteristics from intensively cultivated seaweeds (Saccharina, Undaria and Sargassum - brown seaweeds, and Gracilaria, Kappaphycus and Eucheuma - red seaweeds). While there is some variability in biochar properties as a function of the origin of seaweed, there are several defining and consistent characteristics of seaweed biochar, in particular a relatively low C content and surface area but high yield, essential trace elements (N, P and K) and exchangeable cations (particularly K). The pH of seaweed biochar ranges from neutral (7) to alkaline (11), allowing for broad-spectrum applications in diverse soil types. We find that seaweed biochar is a unique material for soil amelioration that is consistently different to biochar derived from ligno-cellulosic feedstock. Blending of seaweed and ligno-cellulosic biochar could provide a soil ameliorant that combines a high fixed C content with a mineral-rich substrate to enhance crop productivity.

14. 'ANNISQUAM POINT JAN. 4, 1898.' Photocopy of photograph ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. 'ANNISQUAM POINT -- JAN. 4, 1898.' Photocopy of photograph (original glass plate negative #T86 in the collection of the Annisquam Historical Society, Annisquam, Massachusetts). Photographer: Martha Harvey (1862-1949). (The handwritten legend along the top edge of the photograph is scratched in the emulsion of the original glass plate negative. Consequently it reads in reverse when printed.) - Annisquam Bridge, Spanning Lobster Cove between Washington & River Streets, Gloucester, Essex County, MA

CTC Sentinel. Volume 6, Issue 10

DTIC Science & Technology

2013-10-01

and the office of Kenyan President Uhuru Kenyatta.11 Fighting continued into the evening of Tuesday , 6 Daniel Howden, “Terror in Nairobi: The Full...provided Iraq with $1 billion per month starting in 1982. See John Bulloch and Harvey Morris , The Gulf War: Its Origins, History and Consequences (London...Expected,” UN High Commissioner for Refu- gees, September 5, 2013. 25 Biro. 26 Loveday Morris , Joby Warrick and Souad Mekhen- net, “Rival al-Qaeda

Defense and Arms Control Studies Program, Annual Report, 1988-1989

DTIC Science & Technology

1989-09-01

meetings of the U.S. and British History of Science Societies, Manchester, England, July 1988. Sapolsky, Harvey, "The Future of Technology Policy Studies... of Science Societies, Manchester, England "Politics of Weapon Acquisition Corruption," Political Science Seminar, Washington University, St. Louis...December 1988 March 1989 April 1989 "Military Support for Academic Research in the United States," paper at the joint meetings of U.S. and British History

Polycyanurates and Polycarbonates Based on Eugenol: Alternatives to Thermosetting and Thermoplastic Polymers Based on Bisphenol A

DTIC Science & Technology

2014-08-14

to 5a. CONTRACT NUMBER In-House Thermosetting and Thermoplastic Polymers based on Bisphenol A 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6...Francisco, CA, 14 August 2014. PA#14389 14. ABSTRACT Polycyanurate thermosetting networks, polycarbonate thermoplastics, and homogenous polycarbonate...ON EUGENOL: ALTERNATIVES TO THERMOSETTING AND THERMOPLASTIC POLYMES BASED ON BISPHENOL A 14 August 2014 Andrew J. Guenthner1, Benjamin G. Harvey2

Ecological Risk Assessment of Perchlorate in Avian Species, Rodents, Amphibians and Fish: FY2004

DTIC Science & Technology

2006-03-01

subsequently transcribed to the representative protein sequence. The protien sequence was used to generate polyclonal antibodies antisera against the deer...Chemical name: Sea Salts CAS number: Not applicable Characterization: an artificial salt mixture closely resembling the composition of the dissolved...the northern bobwhite (Colinus virginianus). Environ. Toxicol. Chem. 22:381-387. Harvey, S.D., R.J. Fellows. D.A. Cataldo, and R.M. Bean . 1991. Fate

Astronaut John W. Young during water egress training

NASA Image and Video Library

1966-06-18

S66-39691 (18 June 1966) --- Astronaut John W. Young, prime crew command pilot for the Gemini-10 spaceflight, sits in Static Article 5 during water egress training activity onboard the NASA Motor Vessel Retriever. The SA-5 will be placed in the water and he and astronaut Michael Collins will then practice egress and water survival techniques. At right is Gordon Harvey, Spacecraft Operations Branch, Flight Crew Support Division. Photo credit: NASA

Hurricanes Harvey and Irma - High-Resolution Flood Mapping and Monitoring from Sentinel SAR with the Depolarization Reduction Algorithm for Global Observations of InundatioN (DRAGON)

NASA Astrophysics Data System (ADS)

Nghiem, S. V.; Brakenridge, G. R.; Nguyen, D. T.

2017-12-01

Hurricane Harvey inflicted historical catastrophic flooding across extensive regions around Houston and southeast Texas after making landfall on 25 August 2017. The Federal Emergency Management Agency (FEMA) requested urgent supports for flood mapping and monitoring in an emergency response to the extreme flood situation. An innovative satellite remote sensing method, called the Depolarization Reduction Algorithm for Global Observations of inundatioN (DRAGON), has been developed and implemented for use with Sentinel synthetic aperture radar (SAR) satellite data at a resolution of 10 meters to identify, map, and monitor inundation including pre-existing water bodies and newly flooded areas. Results from this new method are hydrologically consistent and have been verified with known surface waters (e.g., coastal ocean, rivers, lakes, reservoirs, etc.), with clear-sky high-resolution WorldView images (where waves can be seen on surface water in inundated areas within a small spatial coverage), and with other flood maps from the consortium of Global Flood Partnership derived from multiple satellite datasets (including clear-sky Landsat and MODIS at lower resolutions). Figure 1 is a high-resolution (4K UHD) image of a composite inundation map for the region around Rosharon (in Brazoria County, south of Houston, Texas). This composite inundation map reveals extensive flooding on 29 August 2017 (four days after Hurricane Harvey made landfall), and the inundation was still persistent in most of the west and south of Rosharon one week later (5 September 2017) while flooding was reduced in the east of Rosharon. Hurricane Irma brought flooding to a number of areas in Florida. As of 10 September 2017, Sentinel SAR flood maps reveal inundation in the Florida Panhandle and over lowland surfaces on several islands in the Florida Keys. However, Sentinel SAR results indicate that flooding along the Florida coast was not extreme despite Irma was a Category-5 hurricane that might have inflicted a potentially strong storm surge. DRAGON flood mapping products over various regions in Texas and in Florida were provided to FEMA. Figure 1. Composite inundation map derived from Sentinel SAR data for the region around Rosharon on 9/5/2017 (orange), inundation on 8/29/2017 (yellow), and pre-existing surface waters on 8/5/2017 (blue).

Tropical Storm Harvey Spotted by NASA's MISR

NASA Image and Video Library

2017-08-29

On Aug. 27, 2017, the Multi-angle Imaging SpectroRadiometer (MISR) instrument on NASA's Terra satellite passed over then-Tropical Storm Harvey about noon local time, the day after the storm first made landfall in Texas as a Category 4 hurricane. The MISR instrument is equipped with nine cameras that observe Earth at different angles over a time period of seven minutes. Geometric information from the multiple camera views is used to compute the cloud top heights, and motion of the clouds during the image sequence is used to calculate wind speed. This composite image shows the storm as viewed by the central, downward-looking camera (left), as well as the cloud top heights in kilometers (center) and the wind speeds (right) superimposed on the image. The length of the arrows is proportional to the wind speed, while their color shows the altitude at which the winds were calculated. Also included is an animation made by combining all nine images from the MISR cameras, showing the motion of the storm during the seven-minute period. At this time, the center of the tropical storm was located just northwest of the city of Victoria and maximum wind speeds on the ground were around 40 miles per hour (65 kilometers per hour) according to the National Oceanic and Atmospheric Administration (NOAA), which matches well with the near-surface winds calculated by MISR to the west of Corpus Christi. In the 36 hours or so since it had made landfall, Harvey had weakened considerably -- these images show that the eye had disappeared and much of the circular motion of storm had dissipated, as shown by the calculated wind directions. However, the area of very high clouds and strong winds near Houston shows that the storm was continuing to produce powerful rain bands. At this point, hydrographs managed by NOAA in downtown Houston were already recording flood stage at both the Buffalo Bayou (28 feet or 8.5 meters as of 12:15 p.m. CDT August 27) and the White Oak Bayou (40 feet or 12 meters at last record that morning). The MISR data show the storm clouds reaching an altitude of about 10 miles (16 kilometers). These data were captured during Terra orbit 94108. An animation is available at https://photojournal.jpl.nasa.gov/catalog/PIA21927

Nowcasting, forecasting and hindcasting Harvey and Irma inundation in near-real time using a continental 2D hydrodynamic model

NASA Astrophysics Data System (ADS)

Sampson, C. C.; Wing, O.; Quinn, N.; Smith, A.; Neal, J. C.; Schumann, G.; Bates, P.

2017-12-01

During an ongoing natural disaster data are required on: (1) the current situation (nowcast); (2) its likely immediate evolution (forecast); and (3) a consistent view post-event of what actually happened (hindcast or reanalysis). We describe methods used to achieve all three tasks for flood inundation during the Harvey and Irma events using a continental scale 2D hydrodynamic model (Wing et al., 2017). The model solves the local inertial form of the Shallow Water equations over a regular grid of 1 arcsecond ( 30m). Terrain data are taken from the USGS National Elevation Dataset with known flood defences represented using the U.S. Army Corps of Engineers National Levee Dataset. Channels are treated as sub-grid scale features using the HydroSHEDS global hydrography data set. The model is driven using river flows, rainfall and coastal water levels. It simulates river flooding in basins > 50 km2, and fluvial and coastal flooding everywhere. Previous wide area validation tests show this model to be capable of matching FEMA maps and USGS local models built with bespoke data with hit rates of 86% and 92% respectively (Wing et al., 2017). Boundary conditions were taken from NOAA QPS data to produce nowcast and forecast simulations in near real time, before updating with NOAA observations to produce the hindcast. During the event simulation results were supplied to major insurers and multi-nationals who used them to estimate their likely capital exposure and to mitigate flood damage to their infrastructure whilst the event was underway. Simulations were validated against modelled flood footprints computed by FEMA and USACE, and composite satellite imagery produced by the Dartmouth Flood Observatory. For the Harvey event, hit rates ranged from 60-84% against these data sources, but a lack of metadata meant it was difficult to perform like-for-like comparisons. The satellite data also appeared to miss known flooding in urban areas that was picked up in the models. Despite these limitations, the validation was able to pick our areas, notably along the Colorado River near Houston, where our model under-performed and identify areas for future development. The study shows that high resolution near real-time inundation predictions over very large areas during complex events with multiple flood drivers are now a reality.

Mems: Platform for Large-Scale Integrated Vacuum Electronic Circuits

DTIC Science & Technology

2017-03-20

SECURITY CLASSIFICATION OF: The objective of the LIVEC advanced study project was to develop a platform for large-scale integrated vacuum electronic ...Distribution Unlimited UU UU UU UU 20-03-2017 1-Jul-2014 30-Jun-2015 Final Report: MEMS Platform for Large-Scale Integrated Vacuum Electronic ... Electronic Circuits (LIVEC) Contract No: W911NF-14-C-0093 COR Dr. James Harvey U.S. ARO RTP, NC 27709-2211 Phone: 702-696-2533 e-mail

Gas Transport Through Channels

DTIC Science & Technology

2009-03-25

van Zijl, P. C. M., Zeidel, M. L., and Agre, P. (1996) Functional analysis of aquaporin 1-deficient red cells. The Colton null phenotype. /. liml...free cytosolic NrVNH4 +. A new analysis of the effects of NH3 vs. NH4 + fluxes on pHs R. Musa-Aziz L.-M. Chen W. F. Boron Department of... tannins in the algae Spirogyra—demonstrated that it is NH< rather than NH4 + that readily crosses the cell membrane. Later, Warburg (1922), Harvey (1911

The Design and Implementation of a Prototype Web-Portal for the Integrated Mobile Alerting System (IMAS)

DTIC Science & Technology

2006-06-01

Deitel , Harvey M., Paul J. Deitel , and Andrew B. Goldberg. 2004. Internet & World Wide Web: How to Program . Third Edition. Upper Saddle River...mobile devices. The proposed design will result in a proof-of-concept solution that demonstrates a way for users to specify how they wish to ...ORGANIZATION OF THE THESIS The following chapters in this thesis explore various technologies and how they may be implemented to support IMAS

The eminent Italian scholar Pietro d'Abano (1250-1315) and his contribution in anatomy.

PubMed

Tsoucalas, Gregory; Karamanou, Marianna; Androutsos, George

2011-01-01

Pietro d'Abano is recognized as a leading figure in the early history of European medical faculties. Translator and scholar, he translated and commented in Latin the doctrines of Greek and Arab physicians and philosophers having an ambitious attempt, to reconcile the opposing views of Arab medicine and Greek natural philosophy. Moreover he was one of the first to claim, three centuries before Harvey, that the heart is the source of blood vessels.

Variability of Venom-Neutralizing Properties of Serum from Snakes of the Colubrid Genus Lampropeltis

DTIC Science & Technology

1992-01-01

venoms of C. atrx , S. m. bar- potentials for C s. scauhatus (type B) venom bouri, or A. c. mokasen showed persistent (Table 2). inflammation and/or edema...SMITH propeltis with these toxins would cause vascu- thality. Other workers have proposed antibody lotoxic effects. Klauber (1956) reported immu...tested, those injected with venom alone. This suggests Harvey (1960) described inhibition of C. atrx that elapid venom myolytic phospholipases Al venom

REACTIONS TO POSITIVE AND NEGATIVE INFORMATION ABOUT THE SELF AS A FUNCTION OF CERTAIN PERSONALITY CHARACTERISTICS OF THE RECIPIENT.

DTIC Science & Technology

discrepancies are compared for groups at three levels of self - esteem . The research is partly a replication of the studies by Harvey, Kelley, and...subsequent to the present one. In presenting individuals at varying levels of self - esteem with discrepant evaluations of themselves, the intent of this...handled within a theoretical model, there is no attempt to state a more comprehensive theory of self - esteem . (Author)

GSFC_201712012_m12793_Storms2017

NASA Image and Video Library

2017-12-01

The 2017 Atlantic hurricane season was among the top ten most active seasons in recorded history. NASA Earth-observing satellites, such as the Global Precipitation Measurement Missions, are helping scientists better understand how storms develop. The unique vantage point of satellites can also help first responders, and this year satellite data helped organizations map out response strategies during hurricanes Harvey, Irma, and María. Host Joy Ng with Scott Braun, Amber Emory, Miguel Roman, and Michael Goodman.

Strategic Forum. Number 285, January 2014. The Flawed Strategic Debate on Syria

DTIC Science & Technology

2014-01-01

that the Syrian regime of 2015 and beyond will not count us among its benefactors. Niccolò Machiavelli wrote, “A prince must imitate the fox and...who_is_in_charge_of_us_syria_policy>. 60 Niccolò Machiavelli , The Prince , trans. Harvey Mansfield (Chicago: University of Chicago Press, 1998), 69...very real possibility that Syria will not fulfill its chemi- cal weapons obligations under the agreement reached in late 2013. For as Machiavelli

Biosynthesis of 3-Dimethylsulfoniopropionate in Marine Algae

DTIC Science & Technology

2000-02-04

Inheritance of glycinebetaine deficiency in sorghum. Crop Sei. 34, 1217-1220. Hall, J.L., Harvey, D.M.R., and Flowers , T.J. (1978) Evidence for the...accumulated by many marine macroalgae and phyto- plankton species (Blunden and Gordon, 1986; Keller et al., 1989) and by certain salt-tolerant flowering ...DMSP path- way in crops or other organisms, it may be necessary to get only as far as DMSHB to achieve a useful degree of osmotic stress resistance

Not In Our Own Backyard: Posse Comitatus and the Challenge of Government Reorganization

DTIC Science & Technology

2007-09-01

political in nature (e.g., the killings at Columbine High School in Colorado). 4. Department of Defense Directive 5107.1, Enclosure 1, January 5, 2001...awareness to AFSOC and joint special operations forces’ aircrews and ground elements conducting high -risk missions worldwide for the Secretary of...Squadron Officers School , the College of Naval Command and Staff, and the Air War College. Lt Col Harvey was the recipient of the Air War College

Diagnosis of Breast Cancer Using Fluorescence and Reflectance Spectroscopy

DTIC Science & Technology

2004-09-01

S. C. Harvey, R. L. Christian , A. Richardson and W. D. Ko, "Large-needle core biopsy: nonmalignant breast abnormalities evaluated with surgical...34 Medical Laser Application 18, 233-248 (2003). 5. Y. Yuanlong, E. J. Celmer, M. Zurawska Szczepaniak and R. R. Alfano , "Excitation spectrum of...Koutcher and R. R. Alfano , "UV reflectance spectroscopy probes DNA and protein changes in human breast tissues," J Clin Laser Med Surg 19, 35-39 (2001

6 Schools that Make a Difference: With the Support of Focus on Results, These Six Schools Beat the Odds by Using Common Sense Strategies in a Focused Effort to Improve Student Achievement

ERIC Educational Resources Information Center

Cudeiro, Amalia; Palumbo, Joe; Leight, Jan; Nelsen, Jeff

2005-01-01

More and more schools in California and across the nation are showing that when school communities accept the possibility and responsibility of bringing all of their students to proficiency levels, they can do amazing things. Six schools located in southern California--Martin Luther King and Harvey of Santa Ana Unified, Morrison Elementary of…

Leptospirosis Survey of Rodents and Domestic Animals in Ethiopia

DTIC Science & Technology

1976-08-01

bovin --. leptospirosis . Amer. J. Vet. Res. 15, 434. Sulzer, C. R., Harvey, T. W., and Galton, M. M, (1968) Comparison of diagnostic technics for the...U.S. DEPARTMENT OF COMMERCE National Technical Inforuation Service AD-A033 991 LEPTOSPIROSIS SURVEY OF RODENTS AND DOMESTIC ANIMALS IN ETHIOPIA NAVAL...34) Domestic animals. Ethiopia. Leptospirosis.Rodents. ien suoy wasa c’r ’ ubtosryds,’C and domestic animals for leptospirosis in 5 sites in western and

A Hybrid Approach to Composite Damage and Failure Analysis Combining Synergistic Damage Mechanics and Peridynamics

DTIC Science & Technology

2017-03-30

Composite Damage and Failure Analysis Combining Synergistic Damage Mechanics and Peridynamics 5b. GRANT NUMBER NOOO 14-16-1-21 73 5c. PROGRAM...ES) 8. PERFORMING ORGANIZATION REPORT NUMBER Texas A&M Engineering Experiment Station (TEES) 400 Harvey Mitchell Parkway, Suite 300 M160 1473 I...Failure Analysis Combining Synergistic Damage Mechanics and Peridynamics Award Number N00014-16-1-2173 DOD-NAVY- Office of Naval Research PI: Ramesh

Formal System Verification for Trustworthy Embedded Systems

DTIC Science & Technology

2011-04-19

microkernel basis. We had previously achieved code- level formal verification of the seL4 microkernel [3]. In the present project, over 12 months with 0.6 FTE...project, we designed and implemented a secure network access device (SAC) on top of the verified seL4 microkernel. The device allows a trusted front...Engelhardt, Rafal Kolan- ski, Michael Norrish, Thomas Sewell, Harvey Tuch, and Simon Winwood. seL4 : Formal verification of an OS kernel. CACM, 53(6):107

Harvey Nininger's 1948 attempt to nationalize Meteor Crater.

NASA Astrophysics Data System (ADS)

Plotkin, H.; Clarke, R. S., Jr.

2008-10-01

Harvey Nininger successfully petitioned the American Astronomical Society to pass a motion in support of nationalizing Meteor Crater, Arizona, at its June 1948 meeting. He alleged that the Barringer family, who held title to the crater, was depriving American citizens of its scenic beauty and scientific value. He then reportedly went on to make the unauthorized—and false—claim that the family would be receptive to a fair purchase offer for the crater. The Barringers, who had not been given advance warning of the petition and were not present at the meeting, felt ambushed. They quickly and forcefully rebutted Nininger’s allegations, made it clear they had no intention of relinquishing their title to the crater, and terminated his exploration rights. What led Nininger to such a curious and self-defeating act? Based on our reading of his voluminous personal correspondence, we conclude that it was rooted primarily in his complex relationship with Frederick Leonard and Lincoln LaPaz, and his desire to establish a national institute for meteoritical research—with them, originally, but after a serious falling out, on his own. Prevented from moving his American Meteorite Museum to the crater rim, Nininger wondered what would happen if the crater was nationalized and made into a public park, with an accompanying tourist center and museum. With characteristic élan, he could picture himself at its head, with a secure salary and adequate space to exhibit his meteorite collection.

Quantification of Interbasin Transfers into the Addicks Reservoir during Hurricane Harvey

NASA Astrophysics Data System (ADS)

Sebastian, A.; Juan, A.; Gori, A.; Maulsby, F.; Bedient, P. B.

2017-12-01

Between August 25 and 30, Hurricane Harvey dropped unprecedented rainfall over southeast Texas causing widespread flooding in the City of Houston. Water levels in the Addicks and Barker reservoirs, built in the 1940s to protect downtown Houston, exceeded previous records by approximately 2 meters. Concerns regarding structural integrity of the dams and damage to neighbourhoods in within the reservoir pool resulted in controlled releases into Buffalo Bayou, flooding an estimated 4,000 additional structures downstream of the dams. In 2016, during the Tax Day it became apparent that overflows from Cypress Creek in northern Harris County substantially contribute to water levels in Addicks. Prior to this event, little was known about the hydrodynamics of this overflow area or about the additional stress placed on Addicks and Barker reservoirs due to the volume of overflow. However, this information is critical for determining flood risk in Addicks Watershed, and ultimately Buffalo Bayou. In this study, we utilize the recently developed HEC-RAS 2D model the interbasin transfer that occurs between Cypress Creek Watershed and Addicks Reservoir to quantify the volume and rate at which water from Cypress enters the reservoir during extreme events. Ultimately, the results of this study will help inform the official hydrologic models used by HCFCD to determine reservoir operation during future storm events and better inform residents living in or above the reservoir pool about their potential flood risk.

Deletion mutants of Harvey ras p21 protein reveal the absolute requirement of at least two distant regions for GTP-binding and transforming activities.

PubMed Central

Lacal, J C; Anderson, P S; Aaronson, S A

1986-01-01

Deletions of small sequences from the viral Harvey ras gene have been generated, and resulting ras p21 mutants have been expressed in Escherichia coli. Purification of each deleted protein allowed the in vitro characterization of GTP-binding, GTPase and autokinase activity of the proteins. Microinjection of the highly purified proteins into quiescent NIH/3T3 cells, as well as transfection experiments utilizing a long terminal repeat (LTR)-containing vector, were utilized to analyze the biological activity of the deleted proteins. Two small regions located at 6-23 and 152-165 residues are shown to be absolutely required for in vitro and in vivo activities of the ras product. By contrast, the variable region comprising amino acids 165-184 was shown not to be necessary for either in vitro or in vivo activities. Thus, we demonstrate that: (i) amino acid sequences at positions 5-23 and 152-165 of ras p21 protein are probably directly involved in the GTP-binding activity; (ii) GTP-binding is required for the transforming activity of ras p21 and by extension for the normal function of the proto-oncogene product; and (iii) the variable region at the C-terminal end of the ras p21 molecule from amino acids 165 to 184 is not required for transformation. Images Fig.2. Fig.4. PMID:3011420

Harvey Cushing Treated the First Known Patient With Carney Complex

PubMed Central

Tsay, Cynthia J.; Stratakis, Constantine A.; Faucz, Fabio Rueda; London, Edra; Stathopoulou, Chaido; Allgauer, Michael; Quezado, Martha; Dagradi, Terry; Spencer, Dennis D.

2017-01-01

Context: Carney complex (CNC) is a syndrome characterized by hyperplasia of endocrine organs and may present with clinical features of Cushing syndrome and acromegaly due to functional adrenal and pituitary gland tumors. CNC has been linked to mutations in the regulatory subunit of protein kinase A type I-alpha (PRKAR1A) gene. Design: Tissue samples were taken from the hypothalamus or thalamus or tumors of patients with pituitary adenomas seen and operated on by neurosurgeon Harvey Cushing between 1913 and 1932. Following DNA extraction, sequencing for genes of interest was attempted, including PRKAR1A, AIP, USP8, GNAS1, and GPR101, to explore the possibility that these mutations associated with acromegaly, CNC, and Cushing syndrome have been conserved over time. Results: We report a patient described by Dr. Cushing in 1914 with a clinical presentation and postmortem findings suggestive of CNC. Genetic sequencing of the hypothalamus and pituitary adenoma revealed a germline heterozygous p.Arg74His mutation in the PRKAR1A gene, a codon previously described as mutated in CNC, but with a novel amino acid change. Conclusions: This patient is, to our knowledge, the first molecularly confirmed individual with CNC. This case demonstrates the power of modern genetics in studying archived tissues and the importance of recording detailed clinical notes in the diagnosis of disease. PMID:29264456

The 100-year flood seems to be changing. Can we really tell?

NASA Astrophysics Data System (ADS)

Ceres, R. L., Jr.; Forest, C. E.; Keller, K.

2017-12-01

Widespread flooding from Hurricane Harvey greatly exceeded the Federal Emergency Management Agency's 100-year flood levels. In the US, this flood level is often used as an important line of demarcation where areas above this level are considered safe, while areas below the line are at risk and require additional flood risk mitigation. In the wake of Harvey's damage, the US media has highlighted at least two important questions. First, has the 100-year flood level changed? Second, is the 100-year flood level a good metric for determining flood risk? To address the first question, we use an Observation System Simulation Experiment of storm surge flood levels and find that gradual changes to the 100-year storm surge level may not be reliably detected over the long lifespans expected of major flood risk mitigation strategies. Additionally, we find that common extreme value analysis models lead to biased results and additional uncertainty when incorrect assumptions are used for the underlying statistical model. These incorrect assumptions can lead to examples of negative learning. Addressing the second question, these findings further challenge the validity of using simple return levels such as the 100-year flood as a decision tool for assessing flood risk. These results indicate risk management strategies must account for such uncertainties to build resilient and robust planning tools that stakeholders desperately need.

Observations of Building Performance under Combined Wind and Surge Loading from Hurricane Harvey

NASA Astrophysics Data System (ADS)

Lombardo, F.; Roueche, D. B.; Krupar, R. J.; Smith, D. J.; Soto, M. G.

2017-12-01

Hurricane Harvey struck the Texas coastline on August 25, 2017, as a Category 4 hurricane - the first major hurricane to reach the US in twelve years. Wind gusts over 130 mph and storm surge as high as 12.5 ft caused widespread damage to buildings and critical infrastructure in coastal communities including Rockport, Fulton, Port Aransas and Aransas Pass. This study presents the methodology and preliminary observations of a coordinated response effort to document residential building performance under wind and storm surge loading. Over a twelve day survey period the study team assessed the performance of more than 1,000 individual, geo-located residential buildings. Assessments were logged via a smartphone application to facilitate rapid collection and collation of geotagged photographs, building attributes and structural details, and structural damage observations. Detailed assessments were also made of hazard intensity, specifically storm surge heights and both wind speed and direction indicators. Preliminary observations and findings will be presented, showing strong gradients in damage between inland and coastal regions of the affected areas that may be due in part to enhanced individual loading effects of wind and storm surge and potentially joint-hazard loading effects. Contributing factors to the many cases of disproportionate damage observed in close proximity will also be discussed. Ongoing efforts to relate building damage to near-surface hazard measurements (e.g., radar, anemometry) in close proximity will also be described.

Optical projects in the Clinic program at Harvey Mudd College

NASA Astrophysics Data System (ADS)

Yang, Q.

2017-08-01

Clinic program is the senior capstone program at Harvey Mudd College (HMC). Multidisciplinary and industry-sponsored projects allow a team of students to solve a real-world problem over one academic year. Over its 50 plus years, Clinic program has completed numerous optics related projects. This report gives an overview of the Clinic program, reviews recent optical projects and discusses how this program supports the learning of the HMC engineering students. A few sample optical projects with more details are presented to provide an insight of what challenges that undergraduates can overcome. Students achieve learning within the optics discipline and the related engineering disciplines. The experiences in these optical projects indicate the great potential to bringing optical hands-on projects into the undergraduate level. Because of the general engineering curriculum at HMC, these projects often work the best with a multidisciplinary nature even if the core of the project is optically focused. Students gain leadership training, oral and written communication skills and experiences in team work. Close relationship with the sponsor liaisons allows for the students to gain skills in professional conduct, management of tight schedule and a specified budget, and it well prepares the students to their engineering practice. Optical projects have their own sets of specific challenges, so it needs to be chosen properly to match the undergraduate skill sets such as those of HMC engineering students.

Changes in physicochemical characteristics and free amino acids of hawthorn (Crataegus pinnatifida) fruits during maturation.

PubMed

Li, Wei-Qin; Hu, Qing-Ping; Xu, Jian-Guo

2015-05-15

In this study, changes in physicochemical characteristics associated with fruit quality and free amino acids were investigated during maturation of hawthorn fruits. Significant differences in these parameters were found during maturation. The color turned progressively from mature green to semi-red, to reach bright red; the shape changed gradually from oval to round or approached round; the size, weight, and edible part (flesh/core ratio) of hawthorns increased while the density of intact fruits did not change. The content of moisture, total soluble sugars, soluble pectin, reduced ascorbic acid, total ascorbic acid, fructose, and sucrose increased while crude protein content decreased significantly. The levels of starch, sucrose, titratable acidity, protopectin, pectin, total free amino acids, and total essential amino acids initially increased and then decreased gradually during maturation. The outcomes of this study provide additional and useful information for fresh consumption and processing as well as utilization of dropped unripe hawthorn fruits. Copyright © 2014 Elsevier Ltd. All rights reserved.

Public and Private Sector Managers: Are They Really That Different?

DTIC Science & Technology

1982-04-01

L. A., Lau, A. W . & Walters , S. K. The job of the Navy civilian executive in headquarters. The Bureaucrat, 1979, 8, 12-18. Burns, T. Management in...the 39th Annual Academy of Management Meetings, August 1979. Lau, A. W ., Broedling, L. A., Walters , S. K., Newman, A. R., & Harvey, P. M. The nature...Stewart, R. Contrasts in management. London: McGraw-Hill, 1976. Tornow , W . W ., & Pinto, P. R. The development of a managerial taxonomy: A system of

United States Air Force Summer Faculty Research Program. Management Report. Volume 2

DTIC Science & Technology

1988-12-01

Weapons Laboratory 64 Realization of Sublayer Relative Dr. Lane Clark Shielding Order in Electromagnetic Topology 65 Diode Laser Probe of Vibrational Dr...34Tunable Diode Laser Measurements of Air-Broadened Linewidths in the v6 Band of H202," AppI. Opt. 25, 1844 (1986). 18. M. A. H. Smith, G. A. Harvey, G...Varghese and R. K. Hanson, "Tunable Diode Laser Measurements of Spectral Parameters of HCN at Room Temperature," J. Quant. Spectrosc. Radiat. Transfer 31

Northeast Artificial Intelligence Consortium Annual Report - 1988. Volume 12. Computer Architectures for Very Large Knowledge Bases

DTIC Science & Technology

1989-10-01

Vol. 18, No. 5, 1975, pp. 253-263. [CAR84] D.B. Carlin, J.P. Bednarz, CJ. Kaiser, J.C. Connolly, M.G. Harvey , "Multichannel optical recording using... Kellog [31] takes a similar approach as ILEX in the sense that it uses existing systems rather than developing specialized hardwares (the Xerox 1100...parallel complexity. In Proceedings of the International Conference on Database Theory, pages 1-30, September 1986. [31] C. Kellog . From data management to

Effects of Surface Structure and of Embedded-Atom Pair Functionals on Adatom Diffusion on FCC Metallic Surfaces

DTIC Science & Technology

1992-11-01

total-energy calculations that this complex mechanism for diffusion can be invoked for surface self-diffusion on the (100) surface ( Kellog and...Woodland Hills, CA 91364 National Science Foundation 3 SRI International ATIN: A.B. Harvey ATIN: G. Smith Washington, DC 20550 D. Crosley D. Golden...Aeronautics and Astronautics ATTN: H. Krier ATfN: J.R. Osborn 144MEB, 1206 W. Green St. Grissom Hall Urbana, IL 61801 West Lafayette, IN 47906 The Johns

13. 'WAITING AT THE DRAWBRIDGE.' THE COAL SCHOONER LUCY MAY ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. 'WAITING AT THE DRAWBRIDGE.' THE COAL SCHOONER LUCY MAY WAITING AT THE DRAW, JUNE 19, 1896. Photocopy of photograph (original glass plate negative #T89 in the collection of the Annisquam Historical Society, Annisquam, Massachusetts). Photographer: Martha Harvey (1862-1949). (The handwritten legend along the top edge of the photograph is scratched in the emulsion of the original glass plate negative. Consequently it reads in reverse when printed.) - Annisquam Bridge, Spanning Lobster Cove between Washington & River Streets, Gloucester, Essex County, MA

Collecting Micrometeorites from the South Pole Water Well

DTIC Science & Technology

1997-05-01

Susan Taylor, James H. Lever, Ralph P. Harvey, and May 1997 John Govoni C R R EL R EP O R T 9 7 -1 Collecting Micrometeorites from the South Pole ...Water Well Abstract: A collector was designed and built to retrieve micrometeorites from the floor of the South Pole Water Well. The large volume of...firn and ice being melted for the well and the low component of terrestrial material in Antarctic ice make the South Pole Water Well an ideal place to

VizieR Online Data Catalog: YSOs in California Molecular Cloud (Lada+, 2017)

NASA Astrophysics Data System (ADS)

Lada, C. J.; Lewis, J. A.; Lombardi, M.; Alves, J.

2018-01-01

The CMC was observed by the all-sky Planck observatory and by the Herschel Space Observatory as part of the "Auriga-California" program (Harvey et al. 2013, Cat J/ApJ/764/133). The Herschel data we used consisted of observations obtained in parallel mode simultaneously using the PACS and SPIRE instruments. For the purposes of this study we use Herschel observations made in the PACS 160um band, and the SPIRE 250um, 350um and 500um bands. (1 data file).

75 FR 68970 - Amendment of Using Agency for Restricted Areas R-5301; R-5302A, B, and C; and R-5313A, B, C and D...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-10

...-1071; Airspace Docket No. 10-ASO-28] RIN 2120-AA66 Amendment of Using Agency for Restricted Areas R-5301; R-5302A, B, and C; and R-5313A, B, C and D; NC AGENCY: Federal Aviation Administration (FAA), DOT... restricted areas R-5301 Albemarle Sound, NC; R-5302A, B and C, Harvey Point, NC; and R-5313A, B, C and D...

Reducing an Insurgency’s Foothold: Using Army Sustainability Concepts as a Tool of Security Cooperation for AFRICOM

DTIC Science & Technology

2008-03-04

journal on-line]; available from http://www.cfr.org/publication/ 13255 /; Internet; accessed 5 November 2007. 3 Vince Crawley, USINFO Staff Writer, “U.S...Pentagon’s New Africa Command”, Council on Foreign Relations; 3 May 2007 [journal on-line]; available from http://www.cfr.org/publication/ 13255 ...available from http://www.cfr.org/publication/ 13255 /; Internet; accessed 5 November 2007. Harvey, Francis J. and Schoomaker ,Peter J., General, “2007

PFGE, Lior Serotype, and Antimicrobial Resistance Patterns Among Campylobacter jejuni Isolated from Travelers and US Military Personnel with Acute Diarrhea in Thailand, 1998-2003

DTIC Science & Technology

2010-01-01

subtyping Salmonella spp., Shigella spp., and Vibrio spp., in addition to C. jejttni 112,13]. Unlike other enteric bacteria, Campylobacter is a...Campylobacter jejuni and Campylobacter col/Isolated from raw chicken meat and human stools in Korea. J Food Prot 2006, 69:2915-2923. 7. Harvey SM...coli 01 57:H7, non-typhoidal Salmonella serotypes, and Shigella sonnei by pulsed-field gel electrophoresis (PFGE). PulseNet 8th Annual Update

The Role of Mitochondrial TCA Cycle Enzymes in Determining Prostate Cancer Chemosensitivity

DTIC Science & Technology

2014-03-01

phosphorylation, Nat Rev Genet 2, 342-352. 17. Higgins , L. H., Withers, H. G., Garbens, A., Love, H. D., Magnoni, L., Hayward, S. W., and Moyes, C. D. (2009...MalateDehydrogenase 2ConfersDocetaxel Resistancevia Regulations of JNKSignaling andOxidativeMetabolism Qiong Liu, Chris T. Harvey, Hao Geng, Changhui...1036 Liuet al. The Prostate 40. Higgins LH, Withers HG, Garbens A, Love HD, Magnoni L, Hayward SW, Moyes CD. Hypoxia and the metabolic pheno- type of

Complementation of Myelodysplastic Syndrome Clones with Lentivirus Expression Libraries

DTIC Science & Technology

2012-07-01

Description HRAS Homo sapiens v-Ha-ras Harvey rat sarcoma viral oncogene homolog (HRAS), transcript 1 CDC25C Homo sapiens cell division cycle 25...homolog C (CDC25C), transcript variant 1 MYC Homo sapiens v-myc myeloctomatosis viral oncogene homolog (avian) (MYC) MAP3K7 Homo sapiens mitogen...activated protein kinase kinase kinase 7 (MAP3K7) MAP3K8 Homo sapiens mitogen-activated protein kinase kinase kinase 8 (MAP3K8) SF3B1 Homo sapiens splicing

Complementation of Myelodysplastic Syndrome Clones with Lentivirus Expression Libraries

DTIC Science & Technology

2013-01-01

Description HRAS Homo sapiens v-Ha-ras Harvey rat sarcoma viral oncogene homolog (HRAS), transcript 1 CDC25C Homo sapiens cell division cycle 25...homolog C (CDC25C), transcript variant 1 MYC Homo sapiens v-myc myeloctomatosis viral oncogene homolog (avian) (MYC) MAP3K7 Homo sapiens mitogen...activated protein kinase kinase kinase 7 (MAP3K7) MAP3K8 Homo sapiens mitogen-activated protein kinase kinase kinase 8 (MAP3K8) SF3B1 Homo sapiens

Repair, Evaluation, Maintenance, and Rehabilitation Research Program: Evaluation of Civil Works Metal Structures

DTIC Science & Technology

1991-01-01

can be per- formed at any time, as a spot check, or periodically. Liauid Penetrant Inspection (PT) 19. Aplication . Liquid penetrant testing (PT) is a...increases the inspection \\MAGNE TIC PARTICLESiA - CRACK- Figure 6. Crack in bar magnet attracting magnetic particles 14 particle mobility and enables the...923-9800 or (312) 474-5860 Service: IA, IL, IN, MI, WI LOUISIANA O.S.I. Mobile Lab, Inc. X-Ray Inspection, Inc. P. 0. Box 395 P. 0. Box 51651 Harvey

A Hybrid Approach to Composite Damage and Failure Analysis Combining Synergistic Damage Mechanics and Peridynamics

DTIC Science & Technology

2016-12-31

PERFORMING ORGANIZATION REPORT NUMBER Texas A&M Engineering Experiment Station (TEES) 400 Harvey Mitchell Parkway, Suite 300 M1601473 I 505170-0000112...likely to influence the quasi -static and dynamic crack growth in the composite system. For this step we need a method that reduces/eliminates stress...1 0 7 0 E 0 E _, - 5 _, Fig. 2.1. Quasi -static stretching of an elastic material. Bottom row shows the horizontal displacement obtained with

Glyco-Immune Diagnostic Signatures and Therapeutic Targets of Mesothelioma

DTIC Science & Technology

2012-07-01

are those of the author (s) and should not be construed as an official Department of the Army position, policy or decision unless so designated by...Therapeutic Targets of Mesothelioma 5b. GRANT NUMBER W81XWH-10-1-0399 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR (S) 5d. PROJECT NUMBER Harvey Pass... AUTHOR (S) W91ZSQ9305N632 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER New York University School of Medicine,550

Older Workers in the Market for Part-Time Employment. Appendices to PP 396.

DTIC Science & Technology

1983-09-01

Ehrenberg, R.G., Fringe Benefits and Overtime Behavior. Lexington, 1971. Levis, H. G., "Interes del Employeador en las Horas de Tobajo del Empleado...34 "The Employer Interest in Employees’ Hours of Work," Cuadernos de Economia , 18 (1969), pp. 38-54, summarized in Rosen, Harvey, reference below. Owen...just tangential to the g(h) function. The next question is: Which factors shift the optimum combination of h and c? C-I D * .k=* ~ .... LA A U..~..’ 4 g

Anomaly inflow on QCD axial domain-walls and vortices

NASA Astrophysics Data System (ADS)

Fukushima, Kenji; Imaki, Shota

2018-06-01

We study the chiral effective theory in the presence of quantum chromodynamics (QCD) vortices. Gauge invariance requires novel terms from vortex singularities in the gauged Wess-Zumino-Witten action, which incorporate anomaly-induced currents along the vortices. We examine these terms for systems with QCD axial domain-walls bounded by vortices (vortons) under magnetic fields. We discuss how the baryon and electric charge conservations are satisfied in these systems through interplay between domain-walls and vortices, manifesting Callan-Harvey's mechanism of anomaly inflow.

Race, Income Inequality, and Impervious Surfaces in Relation to Flooding Associated with Hurricane Harvey

NASA Astrophysics Data System (ADS)

de Sherbinin, A. M.; Mills, J.; Borkovska, O.

2017-12-01

Differential vulnerability is a concept that suggests that certain demographic groups - the poor, less educated, or minorities - are likely to be more impacted by climate extremes such as floods owing to their higher sensitivity and lower adaptive capacity. Differential exposure represents the concept that these same groups may be more highly exposed to flood events by virtue of their residing in less desirable, low-lying neighborhoods with higher percentages of impervious surface cover. This paper tests the hypothesis that poor communities of color were differentially exposed to flood risks in the aftermath of Hurricane Harvey, which struck Houston, Texas in August 2017. We explore the spatial relationship among census tracts with high percentages of low income communities of color, those with high percentages of impervious surface, and those most impacted by floods. We incorporat datasets disseminated by the NASA Socioeconomic Data and Application Center (SEDAC) - the Global Man-made Impervious Surface (GMIS) data set and the U.S. Census Grids 2010 - together with the American Community Survey (ACS) 2011-2015 and flood extent and depth data from FEMA. Preliminary analysis suggests that predominantly non-white neighborhoods have higher percentages of impervious surface cover, but that impervious surface cover is negatively correlated with flood risk. This paper will situate these findings in the context of a larger body of research exploring differential exposure to flood risks during Hurricanes Katrina and Sandy, as well as differential exposure to extreme heat in urban environments in Houston and beyond.

Ibn nafis - a forgotten genius in the discovery of pulmonary blood circulation.

PubMed

Akmal, M; Zulkifle, M; Ansari, Ah

2010-03-01

Scientific theories take centuries to come into existence and they keep on evolving. Uncountable intellectual minds work on these theories; some fail to do anything about it; some add a little after tremendous efforts, and some people give remarkable and unforgettable contribution.As far as credit is concerned, the person who is able to prove the theory by his facts and who clears the maximum doubts by his observations, experimentations, facts and reasoning, gets the credit for that theory, and this should be done with honesty.The theory of pulmonary circulation took more than 2000 years to come into existence as we know it today. With the passage of time different people were given credit. Some say that it was given to Galen; some say it was Michael Servetus; others say that Realdus Columbus was the real discoverer; some gave the credit to Ibn Nafis, and finally people gave the credit to William Harvey. But after the rediscovery of Ibn Nafis' manuscript no.62243 titled Sharah al Tashreeh al Qanoon, or "Commentary on the anatomy of Canon of Avicenna" in 1924 AD in Europe, it became clear that Ibn Nafis had described the pulmonary circulation almost 300 years before Harvey, and the historians like Aldo Mieli, Max Mayrhoff, Edward Coppola etc. clearly state that Ibn Nafis is the real discoverer of the pulmonary circulation and that he should be given the credit for the discovery of the pulmonary circulation.

Development of anatomophysiologic knowledge regarding the cardiovascular system: from Egyptians to Harvey.

PubMed

Bestetti, Reinaldo Bulgarelli; Restini, Carolina Baraldi A; Couto, Lucélio B

2014-12-01

Our knowledge regarding the anatomophysiology of the cardiovascular system (CVS) has progressed since the fourth millennium BC. In Egypt (3500 BC), it was believed that a set of channels are interconnected to the heart, transporting air, urine, air, blood, and the soul. One thousand years later, the heart was established as the center of the CVS by the Hippocratic Corpus in the medical school of Kos, and some of the CVS anatomical characteristics were defined. The CVS was known to transport blood via the right ventricle through veins and the pneuma via the left ventricle through arteries. Two hundred years later, in Alexandria, following the development of human anatomical dissection, Herophilus discovered that arteries were 6 times thicker than veins, and Erasistratus described the semilunar valves, emphasizing that arteries were filled with blood when ventricles were empty. Further, 200 years later, Galen demonstrated that arteries contained blood and not air. With the decline of the Roman Empire, Greco-Roman medical knowledge about the CVS was preserved in Persia, and later in Islam where, Ibn Nafis inaccurately described pulmonary circulation. The resurgence of dissection of the human body in Europe in the 14th century was associated with the revival of the knowledge pertaining to the CVS. The main findings were the description of pulmonary circulation by Servetus, the anatomical discoveries of Vesalius, the demonstration of pulmonary circulation by Colombo, and the discovery of valves in veins by Fabricius. Following these developments, Harvey described blood circulation.

Development of Anatomophysiologic Knowledge Regarding the Cardiovascular System: From Egyptians to Harvey.

PubMed

Bestetti, Reinaldo Bulgarelli; Restini, Carolina Baraldi A; Couto, Lucélio B

2014-10-10

Our knowledge regarding the anatomophysiology of the cardiovascular system (CVS) has progressed since the fourth millennium BC. In Egypt (3500 BC), it was believed that a set of channels are interconnected to the heart, transporting air, urine, air, blood, and the soul. One thousand years later, the heart was established as the center of the CVS by the Hippocratic Corpus in the medical school of Kos, and some of the CVS anatomical characteristics were defined. The CVS was known to transport blood via the right ventricle through veins and the pneuma via the left ventricle through arteries. Two hundred years later, in Alexandria, following the development of human anatomical dissection, Herophilus discovered that arteries were 6 times thicker than veins, and Erasistratus described the semilunar valves, emphasizing that arteries were filled with blood when ventricles were empty. Further, 200 years later, Galen demonstrated that arteries contained blood and not air. With the decline of the Roman Empire, Greco-Roman medical knowledge about the CVS was preserved in Persia, and later in Islam where, Ibn Nafis inaccurately described pulmonary circulation. The resurgence of dissection of the human body in Europe in the 14th century was associated with the revival of the knowledge pertaining to the CVS. The main findings were the description of pulmonary circulation by Servetus, the anatomical discoveries of Vesalius, the demonstration of pulmonary circulation by Colombo, and the discovery of valves in veins by Fabricius. Following these developments, Harvey described blood circulation.

Development of Anatomophysiologic Knowledge Regarding the Cardiovascular System: From Egyptians to Harvey

PubMed Central

Bestetti, Reinaldo Bulgarelli; Restini, Carolina Baraldi A.; Couto, Lucélio B.

2014-01-01

Our knowledge regarding the anatomophysiology of the cardiovascular system (CVS) has progressed since the fourth millennium BC. In Egypt (3500 BC), it was believed that a set of channels are interconnected to the heart, transporting air, urine, air, blood, and the soul. One thousand years later, the heart was established as the center of the CVS by the Hippocratic Corpus in the medical school of Kos, and some of the CVS anatomical characteristics were defined. The CVS was known to transport blood via the right ventricle through veins and the pneuma via the left ventricle through arteries. Two hundred years later, in Alexandria, following the development of human anatomical dissection, Herophilus discovered that arteries were 6 times thicker than veins, and Erasistratus described the semilunar valves, emphasizing that arteries were filled with blood when ventricles were empty. Further, 200 years later, Galen demonstrated that arteries contained blood and not air. With the decline of the Roman Empire, Greco-Roman medical knowledge about the CVS was preserved in Persia, and later in Islam where, Ibn Nafis inaccurately described pulmonary circulation. The resurgence of dissection of the human body in Europe in the 14th century was associated with the revival of the knowledge pertaining to the CVS. The main findings were the description of pulmonary circulation by Servetus, the anatomical discoveries of Vesalius, the demonstration of pulmonary circulation by Colombo, and the discovery of valves in veins by Fabricius. Following these developments, Harvey described blood circulation. PMID:25590934

Combining Passive Microwave Sounders with CYGNSS information for improved retrievals: Observations during Hurricane Harvey

NASA Astrophysics Data System (ADS)

Schreier, M. M.

2017-12-01

The launch of CYGNSS (Cyclone Global Navigation Satellite System) has added an interesting component to satellite observations: it can provide wind speeds in the tropical area with a high repetition rate. Passive microwave sounders that are overpassing the same region can benefit from this information, when it comes to the retrieval of temperature or water profiles: the uncertainty about wind speeds has a strong impact on emissivity and reflectivity calculations with respect to surface temperature. This has strong influences on the uncertainty of retrieval of temperature and water content, especially under extreme weather conditions. Adding CYGNSS information to the retrieval can help to reduce errors and provide a significantly better sounder retrieval. Based on observations during Hurricane Harvey, we want to show the impact of CYGNSS data on the retrieval of passive microwave sensors. We will show examples on the impact on the retrieval from polar orbiting instruments, like the Advanced Technology Microwave Sounder (ATMS) and AMSU-A/B on NOAA-18 and 19. In addition we will also show the impact on retrievals from HAMSR (High Altitude MMIC Sounding Radiometer), which was flying on the Global Hawk during the EPOCH campaign. We will compare the results with other observations and estimate the impact of additional CYGNSS information on the microwave retrieval, especially on the impact in error and uncertainty reduction. We think, that a synergetic use of these different data sources could significantly help to produce better assimilation products for forecast assimilation.

Program for developing leadership in pharmacy residents.

PubMed

Fuller, Patrick D

2012-07-15

An innovative, structured approach to incorporating leadership development activities into pharmacy residency training is described. The American Society of Health-System Pharmacists (ASHP) has called for increased efforts to make leadership development an integral component of the training of pharmacy students and new practitioners. In 2007, The Nebraska Medical Center (TNMC) took action to systematize leadership training in its pharmacy residency programs by launching a new Leadership Development Series. Throughout the residency year, trainees at TNMC participate in a variety of activities: (1) focused group discussions of selected articles on leadership concepts written by noted leaders of the past and present, (2) a two-day offsite retreat featuring trust-building exercises and physical challenges, (3) a self-assessment designed to help residents identify and use their untapped personal strengths, (4) training on the effective application of different styles of communication and conflict resolution, and (5) education on the history and evolution of health-system pharmacy, including a review and discussion of lectures by recipients of ASHP's Harvey A. K. Whitney Award. Feedback from residents who have completed the series has been positive, with many residents indicating that it has stimulated their professional growth and helped prepared them for leadership roles. A structured Leadership Development Series exposes pharmacy residents to various leadership philosophies and principles and, through the study of Harvey A. K. Whitney Award lectures, to the thoughts of past and present pharmacy leaders. Residents develop an increased self-awareness through a resident fall retreat, a StrengthsFinder assessment, and communication and conflict-mode assessment tools.

Properties and Residual Stresses in Angle-Ply Polymer Matrix Composites

DTIC Science & Technology

1982-03-01

AMMRC TR 82-12 PROPERTIES AND RES l DUAL STRESSES IN ANGLE-PLY POLYMER MATR l X COMPOSITES March 1982 ABDEL A. FAHMY,, HARVEY A. WEST, and MARK...m D.e. Enl.r.d) PROPERTIES AND RESIDUAL STRESSES I N ANGLE-PLY F i n a l Report POLYMER MATRIX COMPOSITES REPORTDOCUMENTATlON PAGE I 7. AUTHOR...SUPPLEMENTARV NOTES L 19. KEY WORDS (Comclrm. m r.r.r. wd. 11 ner..sw and idenllfy by blocb nmb-r) Composites Thermal expansion Epoxy l a m i n a t e s

44. Photocopy of photograph (negative made from original photograph on ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

44. Photocopy of photograph (negative made from original photograph on file at Veterans Administration in Wichita, Kansas), government photograph certified by W.B. Hayes, Jr., Superintendent of Construction, Veterans Administration, photographic firm Carlson and Bull, 4 May 1934, listed as "Project VAC-0206, no. 9 of 10 views, set no. 2 of 2 sets, subject - Shrubbery and Plantings, contractor Williams & Harvey Nurseries Co., Kansas City, Kansas." View southeast, Building 8 - Veterans Administration Center, Officers Duplex Quarters, 5302 East Kellogg (Legal Address); 5500 East Kellogg (Common Address), Wichita, Sedgwick County, KS

Don't Mess with the NEST

DOE Office of Scientific and Technical Information (OSTI.GOV)

Larson, M

NEST stands for Nuclear Emergency Support Team. The NEST Mission Statement as first established: (1) Conduct, direct, coordinate search and recovery operations for nuclear material, weapons or devices; and (2) Assist in identification and deactivation of Improvised Nuclear Devices (INDs) and Radiological Dispersal Devices (RDDs). Then in 1980 a very sophisticated improvised explosive device was found at Harvey's Casino at Lake Tahoe, Nevada. The FBI and Bomb Squads were unprepared and it detonated. As a result the additional phrase 'and Sophisticated Improvised Explosive Devices (SIEDs)' was added to the Mission Statement.

Alterations in Hormone Production and Utilization During Infection

DTIC Science & Technology

1981-01-01

Reza , M. and Solomon, D. H. (1975) J. Clin. Endocrinol. Metab. 41, 1043-1049. Coleman, T. J., Gamble, D. R., and Taylor, K. W. (1973) Br. Med. J. 3...and Kohn, L. D. (1978) Endocrinology 102, 844-851. Harvey, R. F. (1971) Lancet 1, 208-212. Hassan, A. I., Zeitoun, M. M., Hussein, Z. M., Fahmy , M. S...Woeber, K. A. and Ingbar, S. H. (1973) J. Cliii. Invest. 52, 1796-1803. Zeitoun, M. M., Hassan, A. I., Hussein, Z. M., Fahmy , M. S., Ragab M. and Hussein

POST-BIONIAN DEVELOPMENTS IN PSYCHOANALYTIC FIELD THEORY: THE CONTRIBUTIONS OF ANTONINO FERRO AND GIUSEPPE CIVITARESE.

PubMed

Katz, S Montana

2017-04-01

The Bi-Personal Field: Experiences in Child Psychoanalysis. By Antonino Ferro. New York: Routledge, 1992 (1999). 232 pp. The Intimate Room: Theory and Technique of the Analytic Field. By Giuseppe Civitarese. New York: Routledge, 2008 (2010). 240 pp. The Necessary Dream: New Theories and Techniques of Interpretation in Psychoanalysis. By Giuseppe Civitarese; translated by Ian Harvey. London: Karnac, 2013 (2014). 246 pp. The Analytic Field and Its Transformations. By Antonino Ferro and Giuseppe Civitarese. London: Karnac, 2015. 224 pp. © 2017 The Psychoanalytic Quarterly, Inc.

Fluid Dynamics of Three-Dimensional Turbulent Shear Flows and Transition: Conference Proceedings of the Symposium of the Fluid Dynamics Panel Held in Cesme (Turkey) on 3-6 October 1988

DTIC Science & Technology

1989-04-01

1984), Herbert (1985, 1988), Singer ct al . (1986, 1987), and Saic (1985a,b, 1986). A renewed interest in problems of stability and transio iii swcpt...1981), Montoya et at. (1981), Harvey & Pride (1982), Pearce (1982a,b), Pearce et al . (1982), Tuttle & Maddalon (1982), Boeing Commercial Airplane...Company (1982, 1984), Etchberger (1983), Hanks et al . (1983), Wagner & Fischer (1983, 1984), Douglas Aircraft Company (1984), Holmes (1984), Runyan Ct al

Observed Near-Surface Currents Four Super Typhoons

DTIC Science & Technology

2014-07-16

floats under category-4 hur- ricane Frances 2004 (D’Asaro et al., 2007 ; Sanford et al., 2011). Maximum current velocities of 2.0 m s−1 and 1.7 m s−1...Teague et al., 2007 ). The observed maximum current velocities and the storm’s track in the earlier studies are listed in Table 1. In addition to current...2011) 1.5 Ivan (2004), Gulf of Mexico Category-4 5.8 ADCP 15 6 Teague et al. ( 2007 ) 2.1 Harvey (2005), Atlantic Tropical storm 6.3 ADCP 5 18 Black

Aurora painting pays tribute to Civil War's end

USGS Publications Warehouse

Love, Jeffrey J.

2015-01-01

In 1865, the same year the war ended, the American landscape artist Frederic Edwin Church unveiledAurora Borealis (pictured above), a dramatic and mysterious painting that can be interpreted in terms of 19th century romanticism, scientific philosophy, and Arctic missions of exploration. Aurora Borealiscan also be viewed as a restrained tribute to the end of the Civil War—a moving example of how science and current events served as the muses of late romantic artists [e.g., Carr, 1994, p. 277; Avery, 2011; Harvey, 2012].