Warning! fire in the ICU.

PubMed

Rispoli, Fabio; Iannuzzi, Michele; De Robertis, Edoardo; Piazza, Ornella; Servillo, Giuseppe; Tufano, Rosalba

2014-06-01

At 5:30 pm on December 17, 2010, shortly after a power failure, smoke filled the Intensive Care Unit (ICU) of Federico II University Hospital in Naples, Italy, triggering the hospital emergency alarm system. Immediately, staff began emergency procedures and alerted rescue teams. All patients were transferred without harm. The smoke caused pharyngeal and conjunctival irritation in some staff members. After a brief investigation, firefighters discovered the cause of the fire was a failure of the Uninterruptible Power Supply (UPS).

Assessment of Power Quality based on Fuzzy Logic and Discrete Wavelet Transform for Nonstationary Disturbances

NASA Astrophysics Data System (ADS)

Sinha, Pampa; Nath, Sudipta

2010-10-01

The main aspects of power system delivery are reliability and quality. If all the customers of a power system get uninterrupted power through the year then the system is considered to be reliable. The term power quality may be referred to as maintaining near sinusoidal voltage at rated frequency at the consumers end. The power component definitions are defined according to the IEEE Standard 1459-2000 both for single phase and three phase unbalanced systems based on Fourier Transform (FFT). In the presence of nonstationary power quality (PQ) disturbances results in accurate values due to its sensitivity to the spectral leakage problem. To overcome these limitations the power quality components are calculated using Discrete Wavelet Transform (DWT). In order to handle the uncertainties associated with electric power systems operations fuzzy logic has been incorporated in this paper. A new power quality index has been introduced here which can assess the power quality under nonstationary disturbances.

Dual-Anode Nickel/Hydrogen Cell

NASA Technical Reports Server (NTRS)

Gahn, Randall F.; Ryan, Timothy P.

1994-01-01

Use of two hydrogen anodes in nickel/hydrogen cell reduces ohmic and concentration polarizations contributing to internal resistance, yielding cell with improved discharging performance compared to single-anode cell. Dual-anode concept incorporated into nickel/hydrogen cells of individual pressure-vessel type (for use aboard spacecraft) and common pressure-vessel type, for use on Earth to store electrical energy from photovoltaic sources, "uninterruptible" power supplies of computer and telephone systems, electric vehicles, and load leveling on power lines. Also applicable to silver/hydrogen and other metal/gas batteries.

Ultracapacitor-Based Uninterrupted Power Supply System

NASA Technical Reports Server (NTRS)

Eichenberg, Dennis J.

2011-01-01

The ultracapacitor-based uninterrupted power supply (UPS) system enhances system reliability; reduces life-of-system, maintenance, and downtime costs; and greatly reduces environmental impact when compared to conventional UPS energy storage systems. This design provides power when required and absorbs power when required to smooth the system load and also has excellent low-temperature performance. The UPS used during hardware tests at Glenn is an efficient, compact, maintenance-free, rack-mount, pure sine-wave inverter unit. The UPS provides a continuous output power up to 1,700 W with a surge rating of 1,870 W for up to one minute at a nominal output voltage of 115 VAC. The ultracapacitor energy storage system tested in conjunction with the UPS is rated at 5.8 F. This is a bank of ten symmetric ultracapacitor modules. Each module is actively balanced using a linear voltage balancing technique in which the cell-to-cell leakage is dependent upon the imbalance of the individual cells. The ultracapacitors are charged by a DC power supply, which can provide up to 300 VDC at 4 A. A constant-voltage, constant-current power supply was selected for this application. The long life of ultracapacitors greatly enhances system reliability, which is significant in critical applications such as medical power systems and space power systems. The energy storage system can usually last longer than the application, given its 20-year life span. This means that the ultracapacitors will probably never need to be replaced and disposed of, whereas batteries require frequent replacement and disposal. The charge-discharge efficiency of rechargeable batteries is approximately 50 percent, and after some hundreds of charges and discharges, they must be replaced. The charge-discharge efficiency of ultracapacitors exceeds 90 percent, and can accept more than a million charges and discharges. Thus, there is a significant energy savings through the efficiency improvement, and there is far less downtime for applications and labor involved in replacing an ultracapacitor versus batteries. Also, the lengthy lifespan of this design would greatly reduce the disposal problems posed by lead acid, nickel cadmium, lithium, and nickel metal hydride batteries. This innovation is recyclable by nature, which further reduces system costs. The disposal of ultracapacitors is simple, as they are constructed of non-hazardous components. They are also safer than batteries in that they can be easily discharged, and left indefinitely in a safe, discharged state where batteries cannot.

Comparison of control structures for a bidirectional high-frequency dc-dc converter

NASA Astrophysics Data System (ADS)

Himmelstoss, Felix A.; Kolar, Johann W.; Zach, Franz C.

1989-08-01

A system for dc-dc power conversion based on a buck-boost converter topology is presented. It makes power flow in both directions possible. The possibility of bidirectional power flow is useful for certain applications, such as uninterruptable power supplies. Starting from a structural diagram the transfer function of the system is derived. The controller for the converter is then designed. It is made up of a simple voltage controller, a voltage controller with an inner loop current controller (cascade control) and with two kinds of state space control. The transfer functions of the different system parts are derived and dimensioning guidelines for the controller sections are presented. The closed loop behavior of the bidirectional converter for the different control structures is analyzed based on simulation using duty cycle averaging. Bodediagrams and step responses are shown.

A seamless ubiquitous emergency medical service for crisis situations.

PubMed

Lin, Bor-Shing

2016-04-01

In crisis situations, a seamless ubiquitous communication is necessary to provide emergency medical service to save people's lives. An excellent prehospital emergency medicine provides immediate medical care to increase the survival rate of patients. On their way to the hospital, ambulance personnel must transmit real-time and uninterrupted patient information to the hospital to apprise the physician of the situation and provide options to the ambulance personnel. In emergency and crisis situations, many communication channels can be unserviceable because of damage to equipment or loss of power. Thus, data transmission over wireless communication to achieve uninterrupted network services is a major obstacle. This study proposes a mobile middleware for cognitive radio (CR) for improving the wireless communication link. CRs can sense their operating environment and optimize the spectrum usage so that the mobile middleware can integrate the existing wireless communication systems with a seamless communication service in heterogeneous network environments. Eventually, the proposed seamless mobile communication middleware was ported into an embedded system, which is compatible with the actual network environment without the need for changing the original system architecture. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Multimode power processor

DOEpatents

O'Sullivan, G.A.; O'Sullivan, J.A.

1999-07-27

In one embodiment, a power processor which operates in three modes: an inverter mode wherein power is delivered from a battery to an AC power grid or load; a battery charger mode wherein the battery is charged by a generator; and a parallel mode wherein the generator supplies power to the AC power grid or load in parallel with the battery. In the parallel mode, the system adapts to arbitrary non-linear loads. The power processor may operate on a per-phase basis wherein the load may be synthetically transferred from one phase to another by way of a bumpless transfer which causes no interruption of power to the load when transferring energy sources. Voltage transients and frequency transients delivered to the load when switching between the generator and battery sources are minimized, thereby providing an uninterruptible power supply. The power processor may be used as part of a hybrid electrical power source system which may contain, in one embodiment, a photovoltaic array, diesel engine, and battery power sources. 31 figs.

Multimode power processor

DOEpatents

O'Sullivan, George A.; O'Sullivan, Joseph A.

1999-01-01

In one embodiment, a power processor which operates in three modes: an inverter mode wherein power is delivered from a battery to an AC power grid or load; a battery charger mode wherein the battery is charged by a generator; and a parallel mode wherein the generator supplies power to the AC power grid or load in parallel with the battery. In the parallel mode, the system adapts to arbitrary non-linear loads. The power processor may operate on a per-phase basis wherein the load may be synthetically transferred from one phase to another by way of a bumpless transfer which causes no interruption of power to the load when transferring energy sources. Voltage transients and frequency transients delivered to the load when switching between the generator and battery sources are minimized, thereby providing an uninterruptible power supply. The power processor may be used as part of a hybrid electrical power source system which may contain, in one embodiment, a photovoltaic array, diesel engine, and battery power sources.

Mission Applicability Assessment of Integrated Power Components and Systems

NASA Technical Reports Server (NTRS)

Raffaelle, R. P.; Hepp, A. F.; Landis, G. A.; Hoffman, D. J.

2002-01-01

The need for smaller lightweight autonomous power systems has recently increased with the increasing focus on micro- and nanosatellites. Small area high-efficiency thin film batteries and solar cells are an attractive choice for such applications. The NASA Glenn Research Center, Johns Hopkins Applied Physics Laboratory, Lithium Power Technologies, MicroSat Systems, and others, have been working on the development of autonomous monolithic packages combining these elements or what are called integrated power supplies (IPS). These supplies can be combined with individual satellite components and are capable of providing continuous power even under intermittent illumination associated with a spinning or Earth orbiting satellite. This paper discusses the space mission applicability, benefits, and current development efforts associated with integrated power supply components and systems. The characteristics and several mission concepts for an IPS that combines thin-film photovoltaic power generation with thin-film lithium ion energy storage are described. Based on this preliminary assessment, it is concluded that the most likely and beneficial application of an IPS will be for small "nanosatellites" or in specialized applications serving as a decentralized or as a distributed power source or uninterruptible power supply.

Reliability considerations of a fuel cell backup power system for telecom applications

NASA Astrophysics Data System (ADS)

Serincan, Mustafa Fazil

2016-03-01

A commercial fuel cell backup power unit is tested in real life operating conditions at a base station of a Turkish telecom operator. The fuel cell system responds to 256 of 260 electric power outages successfully, providing the required power to the base station. Reliability of the fuel cell backup power unit is found to be 98.5% at the system level. On the other hand, a qualitative reliability analysis at the component level is carried out. Implications of the power management algorithm on reliability is discussed. Moreover, integration of the backup power unit to the base station ecosystem is reviewed in the context of reliability. Impact of inverter design on the stability of the output power is outlined. Significant current harmonics are encountered when a generic inverter is used. However, ripples are attenuated significantly when a custom design inverter is used. Further, fault conditions are considered for real world case studies such as running out of hydrogen, a malfunction in the system, or an unprecedented operating scheme. Some design guidelines are suggested for hybridization of the backup power unit for an uninterrupted operation.

DC-DC Type High-Frequency Link DC for Improved Power Quality of Cascaded Multilevel Inverter

NASA Astrophysics Data System (ADS)

Sadikin, Muhammad; Senjyu, Tomonobu; Yona, Atsushi

2013-06-01

Multilevel inverters are emerging as a new breed of power converter options for power system applications. Recent advances in power switching devices enabled the suitability of multilevel inverters for high voltage and high power applications because they are connecting several devices in series without the need of component matching. Usually, a transformerless battery energy storage system, based on a cascaded multilevel inverter, is used as a measure for voltage and frequency deviations. System can be reduced in size, weight, and cost of energy storage system. High-frequency link circuit topology is advantageous in realizing compact and light-weight power converters for uninterruptible power supply systems, new energy systems using photovoltaic-cells, fuel-cells and so on. This paper presents a DC-DC type high-frequency link DC (HFLDC) cascaded multilevel inverter. Each converter cell is implemented a control strategy for two H-bridge inverters that are controlled with the same multicarrier pulse width modulation (PWM) technique. The proposed cascaded multilevel inverter generates lower voltage total harmonic distortion (THD) in comparison with conventional cascaded multilevel inverter. Digital simulations are carried out using PSCAD/EMTDC to validate the performance of the proposed cascaded multilevel inverter.

Reliability Issues in Stirling Radioisotope Power Systems

NASA Technical Reports Server (NTRS)

Schreiber, Jeffrey; Shah, Ashwin

2005-01-01

Stirling power conversion is a potential candidate for use in a Radioisotope Power System (RPS) for space science missions because it offers a multifold increase in the conversion efficiency of heat to electric power and reduced requirement of radioactive material. Reliability of an RPS that utilizes Stirling power conversion technology is important in order to ascertain long term successful performance. Owing to long life time requirement (14 years), it is difficult to perform long-term tests that encompass all the uncertainties involved in the design variables of components and subsystems comprising the RPS. The requirement for uninterrupted performance reliability and related issues are discussed, and some of the critical areas of concern are identified. An overview of the current on-going efforts to understand component life, design variables at the component and system levels, and related sources and nature of uncertainties are also discussed. Current status of the 110 watt Stirling Radioisotope Generator (SRG110) reliability efforts is described. Additionally, an approach showing the use of past experience on other successfully used power systems to develop a reliability plan for the SRG110 design is outlined.

Reliability Issues in Stirling Radioisotope Power Systems

NASA Technical Reports Server (NTRS)

Shah, Ashwin R.; Schreiber, Jeffrey G.

2004-01-01

Stirling power conversion is a potential candidate for use in a Radioisotope Power System (RPS) for space science missions because it offers a multifold increase in the conversion efficiency of heat to electric power and reduced requirement of radioactive material. Reliability of an RPS that utilizes Stirling power conversion technology is important in order to ascertain long term successful performance. Owing to long life time requirement (14 years), it is difficult to perform long-term tests that encompass all the uncertainties involved in the design variables of components and subsystems comprising the RPS. The requirement for uninterrupted performance reliability and related issues are discussed, and some of the critical areas of concern are identified. An overview of the current on-going efforts to understand component life, design variables at the component and system levels, and related sources and nature of uncertainties are also discussed. Current status of the 110 watt Stirling Radioisotope Generator (SRG110) reliability efforts is described. Additionally, an approach showing the use of past experience on other successfully used power systems to develop a reliability plan for the SRG110 design is outlined.

Optically powered active sensing system for Internet Of Things

NASA Astrophysics Data System (ADS)

Gao, Chen; Wang, Jin; Yin, Long; Yang, Jing; Jiang, Jian; Wan, Hongdan

2014-10-01

Internet Of Things (IOT) drives a significant increase in the extent and type of sensing technology and equipment. Sensors, instrumentation, control electronics, data logging and transmission units comprising such sensing systems will all require to be powered. Conventionally, electrical powering is supplied by batteries or/and electric power cables. The power supply by batteries usually has a limited lifetime, while the electric power cables are susceptible to electromagnetic interference. In fact, the electromagnetic interference is the key issue limiting the power supply in the strong electromagnetic radiation area and other extreme environments. The novel alternative method of power supply is power over fiber (PoF) technique. As fibers are used as power supply lines instead, the delivery of the power is inherently immune to electromagnetic radiation, and avoids cumbersome shielding of power lines. Such a safer power supply mode would be a promising candidate for applications in IOT. In this work, we built up optically powered active sensing system, supplying uninterrupted power for the remote active sensors and communication modules. Also, we proposed a novel maximum power point tracking technique for photovoltaic power convertors. In our system, the actual output efficiency greater than 40% within 1W laser power. After 1km fiber transmission and opto-electric power conversion, a stable electric power of 210mW was obtained, which is sufficient for operating an active sensing system.

Effect of global warming on willingness to pay for uninterrupted electricity supply in European nations

NASA Astrophysics Data System (ADS)

Cohen, Jed; Moeltner, Klaus; Reichl, Johannes; Schmidthaler, Michael

2018-01-01

Predicted changes in temperature and other weather events may damage the electricity grid and cause power outages. Understanding the costs of power outages and how these costs change over time with global warming can inform outage-mitigation-investment decisions. Here we show that across 19 EU nations the value of uninterrupted electricity supply is strongly related to local temperatures, and will increase as the climate warms. Bayesian hierarchical modelling of data from a choice experiment and respondent-specific temperature measures reveals estimates of willingness to pay (WTP) to avoid an hour of power outage between €0.32 and €1.86 per household. WTP varies on the basis of season and is heterogeneous between European nations. Winter outages currently cause larger per household welfare losses than summer outages per hour of outage. However, this dynamic will begin to shift under plausible future climates, with summer outages becoming substantially more costly and winter outages becoming slightly less costly on a per-household, per-hour basis.

Flywheel Energy Storage Technology Workshop

NASA Astrophysics Data System (ADS)

Okain, D.; Howell, D.

Advances in recent years of high strength/lightweight materials, high performance magnetic bearings, and power electronics technology has spurred a renewed interest by the transportation, utility, and manufacturing industries in flywheel energy storage (FES) technologies. FES offers several advantages over conventional electrochemical energy storage, such as high specific energy and specific power, fast charging time, long service life, high turnaround efficiency (energy out/energy in), and no hazardous/toxic materials or chemicals are involved. Potential applications of FES units include power supplies for hybrid and electric vehicles, electric vehicle charging stations, space systems, and pulsed power devices. Also, FES units can be used for utility load leveling, uninterruptable power supplies to protect electronic equipment and electrical machinery, and for intermittent wind or photovoltaic energy sources. The purpose of this workshop is to provide a forum to highlight technologies that offer a high potential to increase the performance of FES systems and to discuss potential solutions to overcome present FES application barriers. This document consists of viewgraphs from 27 presentations.

A Prospective Randomized Trial of Apixaban Dosing During Atrial Fibrillation Ablation: The AEIOU Trial.

PubMed

Reynolds, Matthew R; Allison, J Scott; Natale, Andrea; Weisberg, Ian L; Ellenbogen, Kenneth A; Richards, Mark; Hsieh, Wen-Hua; Sutherland, Julie; Cannon, Christopher P

2018-05-01

This study sought to determine whether uninterrupted apixaban would have similar rates of bleeding and thromboembolic events as does minimally interrupted apixaban at the time of atrial fibrillation (AF) ablation and to compare those results with rates in historical patients treated with uninterrupted warfarin. The safety, efficacy, and optimal dosing regimen for apixaban at the time of AF ablation are uncertain. This prospective, multicenter clinical trial enrolled 306 patients undergoing catheter ablation for nonvalvular AF and randomized 300 to uninterrupted versus minimally interrupted (holding 1 dose) periprocedural apixaban. A retrospective cohort of patients treated with uninterrupted warfarin at the same centers was matched to the apixaban-treated subjects for comparison. Endpoints included clinically significant bleeding, major bleeding, and nonhemorrhagic stroke or systemic embolism (SE) from the time of ablation through 30 days. There were no stroke or SE events. Clinically significant bleeding occurred in 11.3% of 150 evaluable patients on uninterrupted apixaban and 9.7% of 145 evaluable patients on interrupted apixaban (risk difference: 1.7% [95% confidence interval: -5.5% to 8.8%]; p = NS). Rates of major bleeding were 1.3% with uninterrupted apixaban, and 2.1% with interrupted (risk difference: -0.7%; p = NS). The rates of clinically significant and major bleeding were similar for all apixaban patients combined (10.5% and 1.7%), compared with the matched warfarin group (9.8% and 1.4%). Both uninterrupted and minimally interrupted apixaban at the time of AF ablation were associated with a very low rate of thromboembolic events, and rates of both major (<2%) and clinically significant bleeding were similar to uninterrupted warfarin. (Apixaban Evaluation of Interrupted Or Uninterrupted Anticoagulation for Ablation of Atrial Fibrillation [AEIOU]; NCT02608099). Copyright © 2018 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

Mini Solar and Sea Current Power Generation System

NASA Astrophysics Data System (ADS)

Almenhali, Abdulrahman; Alshamsi, Hatem; Aljunaibi, Yaser; Almussabi, Dheyab; Alshehhi, Ahmed; Hilal, Hassan Bu

2017-07-01

The power demand in United Arab Emirates is increased so that there is a consistent power cut in our region. This is because of high power consumption by factories and also due to less availability of conventional energy resources. Electricity is most needed facility for the human being. All the conventional energy resources are depleting day by day. So we have to shift from conventional to non-conventional energy resources. In this the combination of two energy resources is takes place i.e. wind and solar energy. This process reviles the sustainable energy resources without damaging the nature. We can give uninterrupted power by using hybrid energy system. Basically this system involves the integration of two energy system that will give continuous power. Solar panels are used for converting solar energy and wind turbines are used for converting wind energy into electricity. This electrical power can utilize for various purpose. Generation of electricity will be takes place at affordable cost. This paper deals with the generation of electricity by using two sources combine which leads to generate electricity with affordable cost without damaging the nature balance. The purpose of this project was to design a portable and low cost power system that combines both sea current electric turbine and solar electric technologies. This system will be designed in efforts to develop a power solution for remote locations or use it as another source of green power.

A Standalone Solar Photovoltaic Power Generation using Cuk Converter and Single Phase Inverter

NASA Astrophysics Data System (ADS)

Verma, A. K.; Singh, B.; Kaushika, S. C.

2013-03-01

In this paper, a standalone solar photovoltaic (SPV) power generating system is designed and modeled using a Cuk dc-dc converter and a single phase voltage source inverter (VSI). In this system, a dc-dc boost converter boosts a low voltage of a PV array to charge a battery at 24 V using a maximum power point tracking control algorithm. To step up a 24 V battery voltage to 360 V dc, a high frequency transformer based isolated dc-dc Cuk converter is used to reduce size, weight and losses. The dc voltage of 360 V is fed to a single phase VSI with unipolar switching to achieve a 230 Vrms, 50 Hz ac. The main objectives of this investigation are on efficiency improvement, reduction in cost, weight and size of the system and to provide an uninterruptible power to remotely located consumers. The complete SPV system is designed and it is modeled in MATLAB/Simulink. The simulated results are presented to demonstrate its satisfactory performance for validating the proposed design and control algorithm.

Trigger circuit forces immediate synchronization of free-running oscillator

NASA Technical Reports Server (NTRS)

Nagano, S.

1975-01-01

Device provides positive triggering for inverter synchronization in uninterruptible power supplies. Integrated-circuit oscillator frequency may be higher, lower, or the same as that of the synch pulse and is always synchronized by first clock pulse.

Paulo Freire and the Contradictions of Literate Democracy.

ERIC Educational Resources Information Center

Gibson, Rich

Democracies of both the East and the West function in a world depression that began 20 years ago and has grown uninterruptedly. Overlaying the economic crisis is the fact that the current economic powers, Germany, Japan, and Russia, are without military might; while the military power, the United States, has virtually no industrial base and an…

Development of Power Supply Management Module for Radio Signal Repeaters of Automatic Metering Reading System in Variable Solar Density Conditions

NASA Astrophysics Data System (ADS)

Kondratjevs, K.; Zabasta, A.; Selmanovs-Pless, V.

2016-02-01

In recent years, there has been significant research focus that revolves around harvesting and minimising energy consumption by wireless sensor network nodes. When a sensor node is depleted of energy, it becomes unresponsive and disconnected from the network that can significantly influence the performance of the whole network. The purpose of the present research is to create a power supply management module in order to provide stable operating voltage for autonomous operations of radio signal repeaters, sensors or gateways of WSN. The developed management module is composed of a solar panel, lithium battery and power supply management module. The novelty of the research is the management module, which ensures stable and uninterrupted operations of electronic equipment in various power supply modes in different situations, simultaneously ensuring energy protection and sustainability of the module components. The management module is able to provide power supply of 5 V for electronics scheme independently, without power interruption switching between power sources and power flows in different directions.

Piezotube borehole seismic source

DOEpatents

Daley, Tom M; Solbau, Ray D; Majer, Ernest L

2014-05-06

A piezoelectric borehole source capable of permanent or semipermanent insertion into a well for uninterrupted well operations is described. The source itself comprises a series of piezoelectric rings mounted to an insulative mandrel internally sized to fit over a section of well tubing, the rings encased in a protective housing and electrically connected to a power source. Providing an AC voltage to the rings will cause expansion and contraction sufficient to create a sonic pulse. The piezoelectric borehole source fits into a standard well, and allows for uninterrupted pass-through of production tubing, and other tubing and electrical cables. Testing using the source may be done at any time, even concurrent with well operations, during standard production.

Solar electric power for instruments at remote sites

USGS Publications Warehouse

McChesney, P.J.

2000-01-01

Small photovoltaic (PV) systems are the preferred method to power instruments operating at permanent locations away from the electric power grid. The low-power PV power system consists of a solar panel or small array of panels, lead-acid batteries, and a charge controller. Even though the small PV power system is simple, the job of supplying power at a remote site can be very demanding. The equipment is often exposed to harsh conditions. The site may be inaccessible part of the year or difficult and expensive to reach at any time. Yet the system must provide uninterrupted power with minimum maintenance at low cost. This requires good design. Successful small PV systems often require modifications by a knowledgeable fieldworker to adapt to conditions at the site. Much information is available in many places about solar panels, lead-acid batteries, and charging systems but very little of it applies directly to low power instrument sites. The discussion here aims to close some of the gap. Each of the major components is described in terms of this application with particular attention paid to batteries. Site problems are investigated. Finally, maintenance and test procedures are given. This document assumes that the reader is engaged in planning or maintaining low-power PV sites and has basic electrical and electronic knowledge. The area covered by the discussion is broad. To help the reader with the many terms and acronyms used, they are shown in bold when first used and a glossary is provided at the end of the paper.

77 FR 3461 - Request for Information (RFI) Regarding Miscellaneous Residential and Commercial Electrical...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-24

... space heating equipment, thermal household equipment, thermal kitchen equipment, uninterruptible power.../or odors from interior dwelling spaces and furniture. Example products include steam cleaners and... equipment. f. Personal Space Heating Equipment This category includes electrical devices that primarily...

A multifunctional energy-storage system with high-power lead-acid batteries

NASA Astrophysics Data System (ADS)

Wagner, R.; Schroeder, M.; Stephanblome, T.; Handschin, E.

A multifunctional energy storage system is presented which is used to improve the utilization of renewable energy supplies. This system includes three different functions: (i) uninterruptible power supply (UPS); (ii) improvement of power quality; (iii) peak-load shaving. The UPS application has a long tradition and is used whenever a reliable power supply is needed. Additionally, nowadays, there is a growing demand for high quality power arising from an increase of system perturbation of electric grids. Peak-load shaving means in this case the use of renewable energy stored in a battery for high peak-load periods. For such a multifunctional application large lead-acid batteries with high power and good charge acceptance, as well as good cycle life are needed. OCSM batteries as with positive tubular plates and negative copper grids have been used successfully for a multitude of utility applications. This paper gives two examples where multifunctional energy storage systems have started operation recently in Germany. One system was installed in combination with a 1 MW solar plant in Herne and another one was installed in combination with a 2 MW wind farm in Bocholt. At each place, a 1.2 MW h (1 h-rate) lead-acid battery has been installed. The batteries consist of OCSM cells with the standard design but modified according to the special demand of a multifunctional application.

Smart intimation and location of faults in distribution system

NASA Astrophysics Data System (ADS)

Hari Krishna, K.; Srinivasa Rao, B.

2018-04-01

Location of faults in the distribution system is one of the most complicated problems that we are facing today. Identification of fault location and severity of fault within a short time is required to provide continuous power supply but fault identification and information transfer to the operator is the biggest challenge in the distribution network. This paper proposes a fault location method in the distribution system based on Arduino nano and GSM module with flame sensor. The main idea is to locate the fault in the distribution transformer by sensing the arc coming out from the fuse element. The biggest challenge in the distribution network is to identify the location and the severity of faults under different conditions. Well operated transmission and distribution systems will play a key role for uninterrupted power supply. Whenever fault occurs in the distribution system the time taken to locate and eliminate the fault has to be reduced. The proposed design was achieved with flame sensor and GSM module. Under faulty condition, the system will automatically send an alert message to the operator in the distribution system, about the abnormal conditions near the transformer, site code and its exact location for possible power restoration.

Large Capacity SMES for Voltage Dip Compensation

NASA Astrophysics Data System (ADS)

Iwatani, Yu; Saito, Fusao; Ito, Toshinobu; Shimada, Mamoru; Ishida, Satoshi; Shimanuki, Yoshio

Voltage dips of power grids due to thunderbolts, snow damage, and so on, cause serious damage to production lines of precision instruments, for example, semiconductors. In recent years, in order to solve this problem, uninterruptible power supply systems (UPS) are used. UPS, however, has small capacity, so a great number of UPS are needed in large factories. Therefore, we have manufactured the superconducting magnetic energy storage (SMES) system for voltage dip compensation able to protect loads with large capacity collectively. SMES has advantages such as space conservation, long lifetime and others. In field tests, cooperating with CHUBU Electric Power Co., Inc. we proved that SMES is valuable for compensating voltage dips. Since 2007, 10MVA SMES improved from field test machines has been running in a domestic liquid crystal display plant, and in 2008, it protected plant loads from a number of voltage dips. In this paper, we report the action principle and components of the improved SMES for voltage dip compensation, and examples of waveforms when 10MVA SMES compensated voltage dips.

Feasibility of energy harvesting techniques for wearable medical devices.

PubMed

Voss, Thaddaeus J; Subbian, Vignesh; Beyette, Fred R

2014-01-01

Wearable devices are arguably one of the most rapidly growing technologies in the computing and health care industry. These systems provide improved means of monitoring health status of humans in real-time. In order to cope with continuous sensing and transmission of biological and health status data, it is desirable to move towards energy autonomous systems that can charge batteries using passive, ambient energy. This not only ensures uninterrupted data capturing, but could also eliminate the need to frequently remove, replace, and recharge batteries. To this end, energy harvesting is a promising area that can lead to extremely power-efficient portable medical devices. This paper presents an experimental prototype to study the feasibility of harvesting two energy sources, solar and thermoelectric energy, in the context of wearable devices. Preliminary results show that such devices can be powered by transducing ambient energy that constantly surrounds us.

Engineering model 8-cm thruster subsystem

NASA Technical Reports Server (NTRS)

Herron, B. G.; Hyman, J.; Hopper, D. J.; Williamson, W. S.; Dulgeroff, C. R.; Collett, C. R.

1978-01-01

An Engineering Model (EM) 8 cm Ion Thruster Propulsion Subsystem was developed for operation at a thrust level 5 mN (1.1 mlb) at a specific impulse 1 sub sp = 2667 sec with a total system input power P sub in = 165 W. The system dry mass is 15 kg with a mercury-propellant-reservoir capacity of 8.75 kg permitting uninterrupted operation for about 12,500 hr. The subsystem can be started from a dormant condition in a time less than or equal to 15 min. The thruster has a design lifetime of 20,000 hr with 10,000 startup cycles. A gimbal unit is included to provide a thrust vector deflection capability of + or - 10 degrees in any direction from the zero position. The EM subsystem development program included thruster optimization, power-supply circuit optimization and flight packaging, subsystem integration, and subsystem acceptance testing including a cyclic test of the total propulsion package.

A highly stable monolithic enhancement cavity for second harmonic generation in the ultraviolet

NASA Astrophysics Data System (ADS)

Hannig, S.; Mielke, J.; Fenske, J. A.; Misera, M.; Beev, N.; Ospelkaus, C.; Schmidt, P. O.

2018-01-01

We present a highly stable bow-tie power enhancement cavity for critical second harmonic generation (SHG) into the UV using a Brewster-cut β-BaB2O4 (BBO) nonlinear crystal. The cavity geometry is suitable for all UV wavelengths reachable with BBO and can be modified to accommodate anti-reflection coated crystals, extending its applicability to the entire wavelength range accessible with non-linear frequency conversion. The cavity is length-stabilized using a fast general purpose digital PI controller based on the open source STEMlab 125-14 (formerly Red Pitaya) system acting on a mirror mounted on a fast piezo actuator. We observe 130 h uninterrupted operation without decay in output power at 313 nm. The robustness of the system has been confirmed by exposing it to accelerations of up to 1 g with less than 10% in-lock output power variations. Furthermore, the cavity can withstand 30 min of acceleration exposure at a level of 3 grms without substantial change in the SHG output power, demonstrating that the design is suitable for transportable setups.

Analyzing the Alternatives

ERIC Educational Resources Information Center

Grayson, Jennifer

2010-01-01

Technologies like solar, wind, and geothermal are exciting, but relatively new and untested in the context of universities, many of which are large enough to be cities unto themselves. And, like cities, universities count on a reliable, uninterruptible source of power. It is imperative, too, that precious dollars are wisely invested in the right…

Water system unreliability and diarrhea incidence among children in Guatemala.

PubMed

Trudeau, Jennifer; Aksan, Anna-Maria; Vásquez, William F

2018-03-01

This article examines the effect of water system unreliability on diarrhea incidence among children aged 0-5 in Guatemala. We use secondary data from a nationally representative sample of 7579 children to estimate the effects of uninterrupted and interrupted water services on diarrhea incidence. The national scope of this study imposes some methodological challenges due to unobserved geographical heterogeneity. To address this issue, we estimate mixed-effects logit models that control for unobserved heterogeneity by estimating random effects of selected covariates that can vary across geographical areas (i.e. water system reliability). Compared to children without access to piped water, children with uninterrupted water services have a lower probability of diarrhea incidence by approximately 33 percentage points. Conversely, there is no differential effect between children without access and those with at least one day of service interruptions in the previous month. Results also confirm negative effects of age, female gender, spanish language, and garbage disposal on diarrhea incidence. Public health benefits of piped water are realized through uninterrupted provision of service, not merely access. Policy implications are discussed.

The Development of a Highly Reliable Power Management and Distribution System for Civil Transport Aircraft

NASA Technical Reports Server (NTRS)

Coleman, Anthony S.; Hansen, Irving G.

1994-01-01

NASA is pursuing a program in Advanced Subsonic Transport (AST) to develop the technology for a highly reliable Fly-By-Light/Power-By-WIre aircraft. One of the primary objectives of the program is to develop the technology base for confident application of integrated PBW components and systems to transport aircraft to improve operating reliability and efficiency. Technology will be developed so that the present hydraulic and pneumatic systems of the aircraft can be systematically eliminated and replaced by electrical systems. These motor driven actuators would move the aircraft wing surfaces as well as the rudder to provide steering controls for the pilot. Existing aircraft electrical systems are not flight critical and are prone to failure due to Electromagnetic Interference (EMI) (1), ground faults and component failures. In order to successfully implement electromechanical flight control actuation, a Power Management and Distribution (PMAD) System must be designed having a reliability of 1 failure in 10(exp +9) hours, EMI hardening and a fault tolerance architecture to ensure uninterrupted power to all aircraft flight critical systems. The focus of this paper is to analyze, define, and describe technically challenging areas associated with the development of a Power By Wire Aircraft and typical requirements to be established at the box level. The authors will attempt to propose areas of investigation, citing specific military standards and requirements that need to be revised to accommodate the 'More Electric Aircraft Systems'.

Standby-battery autonomy versus power quality

NASA Astrophysics Data System (ADS)

Bitterlin, Ian F.

Batteries are used in a wide variety of applications as an energy store to bridge gaps in the primary source of supplied power for a given period of time. In some cases this bridging time, the battery's "autonomy", is fixed by local legislation but it is also often set by historically common practices. However, even if common practice dictates a long autonomy time, we are entering a new era of "cost and benefit realism" underpinned by environmentally friendly policies and we should challenge these historical practices at every opportunity if it can lead to resource and cost savings. In some cases the application engineer has no choice in the design autonomy; either follow a piece of local legislation (e.g. 4 h autonomy for a "life safety" application), or actually work out what is needed! An example of the latter would be for a remote site, off-grid, using integrated wind/solar power (without emergency generator back-up) where you may have to design-in several days' battery autonomy. This short paper proposes that a battery's autonomy should be related to the time expected for the system to be without the primary power source, balanced by the capital costs and commercial risk of power failure. To discuss this we shall consider the factors in selecting the autonomy time and other related aspects for high voltage battery systems used in facility-wide uninterruptible power supply (UPS) systems.

Design and Implementation of Real-Time Off-Grid Detection Tool Based on FNET/GridEye

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guo, Jiahui; Zhang, Ye; Liu, Yilu

2014-01-01

Real-time situational awareness tools are of critical importance to power system operators, especially during emergencies. The availability of electric power has become a linchpin of most post disaster response efforts as it is the primary dependency for public and private sector services, as well as individuals. Knowledge of the scope and extent of facilities impacted, as well as the duration of their dependence on backup power, enables emergency response officials to plan for contingencies and provide better overall response. Based on real-time data acquired by Frequency Disturbance Recorders (FDRs) deployed in the North American power grid, a real-time detection methodmore » is proposed. This method monitors critical electrical loads and detects the transition of these loads from an on-grid state, where the loads are fed by the power grid to an off-grid state, where the loads are fed by an Uninterrupted Power Supply (UPS) or a backup generation system. The details of the proposed detection algorithm are presented, and some case studies and off-grid detection scenarios are also provided to verify the effectiveness and robustness. Meanwhile, the algorithm has already been implemented based on the Grid Solutions Framework (GSF) and has effectively detected several off-grid situations.« less

29. AERIAL VIEW OF THE ROCKY FLATS PLANT LOOKING SOUTH. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

29. AERIAL VIEW OF THE ROCKY FLATS PLANT LOOKING SOUTH. IN 1983, THE PERIMETER SECURITY ZONE SURROUNDING THE PLUTONIUM OPERATIONS WAS COMPLETED. IT CONSISTED OF A DOUBLE PERIMETER FENCE, CLOSED CIRCUIT TELEVISIONS, ALARMS, AND AN UNINTERRUPTED POWER SUPPLY (7/29/83). - Rocky Flats Plant, Bounded by Indiana Street & Routes 93, 128 & 72, Golden, Jefferson County, CO

Software Development for a Satellite Signal Analyzer

DTIC Science & Technology

1979-12-01

uses this mode index. BUTLI3(18,6) 1*4 Is an array of button num- bers used by the subroutine KTLSIM to simulate the user pushing bottons by...either the program SATCOM will be executed, or if HOLD was previously pushed, the array BUTLIS is used to sim- ulate the pushing of the bottons on...in branch 1 to the AW /WSC-3 has to be on. Branches 1-3 provide power to the lab benches, rack 0-6, and uninterruptable power to the time code

Improved Data Acquisition Methods for Uninterrupted Signal Monitoring and Ultra-Fast Plasma Diagnostics in LHD

NASA Astrophysics Data System (ADS)

Nakanishi, Hideya; Imazu, Setsuo; Ohsuna, Masaki; Kojima, Mamoru; Nonomura, Miki; Shoji, Mamoru; Emoto, Masahiko; Yoshida, Masanobu; Iwata, Chie; Miyake, Hitoshi; Nagayama, Yoshio; Kawahata, Kazuo

To deal with endless data streams acquired in LHD steady-state experiments, the LHD data acquisition system was designed with a simple concept that divides a long pulse into a consecutive series of 10-s “subshots”. Latest digitizers applying high-speed PCI-Express technology, however, output nonstop gigabyte per second data streams whose subshot intervals would be extremely long if 10-s rule was applied. These digitizers need shorter subshot intervals, less than 10-s long. In contrast, steady-state fusion plants need uninterrupted monitoring of the environment and device soundness. They adopt longer subshot lengths of either 10 min or 1 day. To cope with both uninterrupted monitoring and ultra-fast diagnostics, the ability to vary the subshot length according to the type of operation is required. In this study, a design modification that enables variable subshot lengths was implemented and its practical effectiveness in LHD was verified.

Economic and Physical Linkages of the Information and Communication Technology (ICT) Service Industry to Key Industries of the Economy: An Ad Hoc Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, David M.; Hoffman, Michael G.; Niemeyer, Jackie M.

This report examines the information and communications technology (ICT) services industry in response to an inquiry by the Department of Energy’s (DOE’s) Office of Energy Policy and Systems Analysis. The report answers several key questions: •How has the reliance on ICT services evolved in recent years for key infrastructure services such as air travel, freight transport, electricity and natural gas distribution, financial services, and critical health care, and for the household sector? •What ICT industry trends explain continued strong linkage to and reliance upon ICT? •What is the ICT industry’s reliance on grid-supplied power, uninterruptible power supplies, emergency generators andmore » back-up energy storage technologies? •What are the observed direct effects of ICT disruptions induced by electrical system failures in recent history and how resilient are the components of the ICT industry?« less

Vascular access site complication in transfemoral coronary angiography between uninterrupted warfarin and heparin bridging.

PubMed

Wongcharoen, Wanwarang; Pinyosamosorn, Kittipong; Gunaparn, Siriluck; Boonnayhun, Suchada; Thonghong, Tasalak; Suwannasom, Pannipa; Phrommintikul, Arintaya

2017-08-01

Warfarin discontinuation with heparin bridging is a common practice in patients receiving warfarin prior to elective coronary angiography (CAG). The uninterrupted warfarin strategy has been suggested to be alternative option for patients with high thromboembolic risk. Therefore, we aimed to assess the safety of elective transfemoral CAG during uninterrupted warfarin therapy compared to heparin bridging. This study was a randomized open-label design with blinded event evaluation. The 110 consecutive patients (age ≥ 18 years) receiving warfarin before the planned transfemoral CAG were randomly assigned to either heparin bridging or uninterrupted warfarin with targeted INR (2.0-3.0). The primary outcome was the incidence of major vascular access site complications. The baseline characteristics were comparable between two groups (mean age was 60.1 ± 7.8 years, 49 males). The mean INR on the day of CAG of heparin bridging and uninterrupted warfarin groups was 1.2 ± 0.3 and 2.2 ± 0.5 (P < 0.001). The major vascular access site complications occurred in 3 of 55 (5.5%) heparin-bridging patients and in none of 55 uninterrupted warfarin patients (P = 0.243). The total vascular access site complications occurred in 6 (10.9%) heparin-bridging and one (1.8%) uninterrupted warfarin patients (P = 0.113). No patient developed either other bleeding or thromboembolic events during 7 days after CAG. We demonstrated that an uninterrupted warfarin strategy did not increase vascular access site complications in patients undergoing transfemoral CAG compared to heparin bridging therapy. Due to the safety and the ease of uninterrupted warfarin strategy, this approach should be encouraged in patients receiving long-term warfarin who undergo elective transfemoral CAG. © 2017, Wiley Periodicals, Inc.

26 CFR 49.4264(c)-1 - Special rule for the payment of tax.

Code of Federal Regulations, 2012 CFR

2012-04-01

... as uninterrupted international air transportation. In the case of a payment for transportation beginning after November 15, 1962, which qualifies as “uninterrupted international air transportation... made and which because of some subsequent event ceases to be uninterrupted international air...

26 CFR 49.4264(c)-1 - Special rule for the payment of tax.

Code of Federal Regulations, 2011 CFR

2011-04-01

... as uninterrupted international air transportation. In the case of a payment for transportation beginning after November 15, 1962, which qualifies as “uninterrupted international air transportation... made and which because of some subsequent event ceases to be uninterrupted international air...

26 CFR 49.4264(c)-1 - Special rule for the payment of tax.

Code of Federal Regulations, 2013 CFR

2013-04-01

... as uninterrupted international air transportation. In the case of a payment for transportation beginning after November 15, 1962, which qualifies as “uninterrupted international air transportation... made and which because of some subsequent event ceases to be uninterrupted international air...

Resonant UPS topologies for the emerging hybrid fiber-coaxial networks

NASA Astrophysics Data System (ADS)

Pinheiro, Humberto

Uninterruptible power supply (UPS) systems have been extensively applied to feed critical loads in many areas. Typical examples of critical loads include life-support equipment, computers and telecommunication systems. Although all UPS systems have a common purpose to provide continuous power-to critical loads, the emerging hybrid fiber-coaxial networks have created the need for specific types of UPS topologies. For example, galvanic isolation for the load and the battery, small size, high input power factor, and trapezoidal output voltage waveforms are among the required features of UPS topologies for hybrid fiber-coaxial networks. None of the conventional UPS topologies meet all these requirements. Consequently. this thesis is directed towards the design and analysis of UPS topologies for this new application. Novel UPS topologies are proposed and control techniques are developed to allow operation at high switching frequencies without penalizing the converter efficiency. By the use of resonant converters in the proposed UPS topologies. a high input power factor is achieved without requiring a dedicated power factor correction stage. In addition, a self-sustained oscillation control method is proposed to ensure soft switching under all operating conditions. A detailed analytical treatment of the resonant converters in the proposed UPS topologies is presented and design procedures illustrated. Simulation and experimental results are presented to validate the analyses and to demonstrate the feasibility of the proposed schemes.

94. VIEW OF LSB (BLDG. 770) EAST EXIT FROM SOUTH ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

94. VIEW OF LSB (BLDG. 770) EAST EXIT FROM SOUTH SIDE OF LANDLINE INSTRUMENTATION ROOM (106). SOUTHWEST CORNER OF UNINTERRUPTABLE POWER SUPPLY (UPS) VISIBLE ON EAST WALL OF LANDLINE INSTRUMENTATION ROOM (106). ROOM 101 ENTRANCE OFF HALLWAY TO LEFT OF EXIT. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

Mitigation of EMI/RFI Produced by a 1.2 kW Uninterruptible Power Supply

DTIC Science & Technology

1993-09-01

930225 1605 NPS, LAB 419, UPS Output Inside Barrer. Black-Green/ Batery 30 MHz, 100 MHz, 30 kHz, 200 ms (LS) 201D, +10, 0, 0, -50 AMPLITUDE - PV -70.79...Figure 52. Voltage Spectrum-Output-Battery Operated 114 LIST OF REFERENCES 1. Adler, R.W., Notes for EC 3640 (Electromagnetic Environ - mental Effects

Flywheel energy storage workshop

DOE Office of Scientific and Technical Information (OSTI.GOV)

O`Kain, D.; Carmack, J.

Since the November 1993 Flywheel Workshop, there has been a major surge of interest in Flywheel Energy Storage. Numerous flywheel programs have been funded by the Advanced Research Projects Agency (ARPA), by the Department of Energy (DOE) through the Hybrid Vehicle Program, and by private investment. Several new prototype systems have been built and are being tested. The operational performance characteristics of flywheel energy storage are being recognized as attractive for a number of potential applications. Programs are underway to develop flywheels for cars, buses, boats, trains, satellites, and for electric utility applications such as power quality, uninterruptible power supplies,more » and load leveling. With the tremendous amount of flywheel activity during the last two years, this workshop should again provide an excellent opportunity for presentation of new information. This workshop is jointly sponsored by ARPA and DOE to provide a review of the status of current flywheel programs and to provide a forum for presentation of new flywheel technology. Technology areas of interest include flywheel applications, flywheel systems, design, materials, fabrication, assembly, safety & containment, ball bearings, magnetic bearings, motor/generators, power electronics, mounting systems, test procedures, and systems integration. Information from the workshop will help guide ARPA & DOE planning for future flywheel programs. This document is comprised of detailed viewgraphs.« less

C-14 beta converter

NASA Astrophysics Data System (ADS)

Gurskaya, A. V.; Dolgopolov, M. V.; Chepurnov, V. I.

2017-11-01

The study discusses the prospects for the development of low-voltage power supply sources. Beta isotope sources present great advantages for autonomous uninterrupted operation of remote devices, which gives an impulse to rapid development of betavoltaics. Silicon carbide homo- and hetero-structures serve as the isotope-based energy converters. We propose a new technology for isotope-based converter fabrication using silicon carbide and carbon-14 heterostructure as the active substance.

Compact, ultra-low vibration, closed-cycle helium recycler for uninterrupted operation of MEG with SQUID magnetometers

NASA Astrophysics Data System (ADS)

Wang, Chao; Sun, Limin; Lichtenwalter, Ben; Zerkle, Brent; Okada, Yoshio

2016-06-01

A closed-cycle helium recycler was developed for continuous uninterrupted operation for magnetometer-based whole-head magnetoencephalography (MEG) systems. The recycler consists of a two stage 4 K pulse-tube cryocooler and is mounted on the roof of a magnetically shielded room (MSR). A flexible liquid helium (LHe) return line on the recycler is inserted into the fill port of the MEG system in the MSR through a slotted opening in the ceiling. The helium vapor is captured through a line that returns the gas to the top of the recycler assembly. A high-purity helium gas cylinder connected to the recycler assembly supplies the gas, which, after it is liquefied, increases the level of LHe in the MEG system during the start-up phase. No storage tank for evaporated helium gas nor a helium gas purifier is used. The recycler is capable of liquefying helium with a rate of ∼17 L/d after precooling the MEG system. It has provided a fully maintenance-free operation under computer control for 7 months without refill of helium. Although the recycler is used for single-orientation operation at this initial testing site, it is designed to operate at ±20° orientations, allowing the MEG system to be tilted for supine and reclining positions. Vibration of the recycler is dampened to an ultra-low level by using several vibration isolation methods, which enables uninterrupted operation during MEG measurements. Recyclers similar to this system may be quite useful even for MEG systems with 100% magnetometers.

EnerCage: A Smart Experimental Arena With Scalable Architecture for Behavioral Experiments

PubMed Central

Uei-Ming Jow; Peter McMenamin; Mehdi Kiani; Manns, Joseph R.; Ghovanloo, Maysam

2014-01-01

Wireless power, when coupled with miniaturized implantable electronics, has the potential to provide a solution to several challenges facing neuroscientists during basic and preclinical studies with freely behaving animals. The EnerCage system is one such solution as it allows for uninterrupted electrophysiology experiments over extended periods of time and vast experimental arenas, while eliminating the need for bulky battery payloads or tethering. It has a scalable array of overlapping planar spiral coils (PSCs) and three-axis magnetic sensors for focused wireless power transmission to devices on freely moving subjects. In this paper, we present the first fully functional EnerCage system, in which the number of PSC drivers and magnetic sensors was reduced to one-third of the number used in our previous design via multicoil coupling. The power transfer efficiency (PTE) has been improved to 5.6% at a 120 mm coupling distance and a 48.5 mm lateral misalignment (worst case) between the transmitter (Tx) array and receiver (Rx) coils. The new EnerCage system is equipped with an Ethernet backbone, further supporting its modular/scalable architecture, which, in turn, allows experimental arenas with arbitrary shapes and dimensions. A set of experiments on a freely behaving rat were conducted by continuously delivering 20 mW to the electronics in the animal headstage for more than one hour in a powered 3538 cm2 experimental area. PMID:23955695

EnerCage: a smart experimental arena with scalable architecture for behavioral experiments.

PubMed

Uei-Ming Jow; McMenamin, Peter; Kiani, Mehdi; Manns, Joseph R; Ghovanloo, Maysam

2014-01-01

Wireless power, when coupled with miniaturized implantable electronics, has the potential to provide a solution to several challenges facing neuroscientists during basic and preclinical studies with freely behaving animals. The EnerCage system is one such solution as it allows for uninterrupted electrophysiology experiments over extended periods of time and vast experimental arenas, while eliminating the need for bulky battery payloads or tethering. It has a scalable array of overlapping planar spiral coils (PSCs) and three-axis magnetic sensors for focused wireless power transmission to devices on freely moving subjects. In this paper, we present the first fully functional EnerCage system, in which the number of PSC drivers and magnetic sensors was reduced to one-third of the number used in our previous design via multicoil coupling. The power transfer efficiency (PTE) has been improved to 5.6% at a 120 mm coupling distance and a 48.5 mm lateral misalignment (worst case) between the transmitter (Tx) array and receiver (Rx) coils. The new EnerCage system is equipped with an Ethernet backbone, further supporting its modular/scalable architecture, which, in turn, allows experimental arenas with arbitrary shapes and dimensions. A set of experiments on a freely behaving rat were conducted by continuously delivering 20 mW to the electronics in the animal headstage for more than one hour in a powered 3538 cm(2) experimental area.

An overview of flywheel energy systems with HTS bearings

NASA Astrophysics Data System (ADS)

Wolsky, A. M.

2002-05-01

Passive magnetic bearings incorporating permanent magnets and ReBaCuO, together with carbon fibre, offer the possibility of increasing the stored, volumetric energy density of FES and unprecedentedly low idling loss of FES. Its stored energy need only satisfy customers' needs for the time it takes to bring on conventional 'back-up'. The FES itself must come up to power quickly enough to avoid any disruption in the customer's operation (e.g., continuous industrial processes involving fragile materials, for example paper forming). Such customers do not care about the price of electricity nearly as much as they care about not ruining their product, damaging their machines or having 'clean ups' that stop or slow output. Firms that engage in electronic commerce and/or telecommunications also value uninterruptible power. Another set of potential customers (construction, electric railroads) may wish to avoid fluctuations in their electrical supply or they may wish to avoid causing harm to others who may hold them liable for poor power quality. Finally, real time prices (e.g., every 15 s) and real time commands, disseminated via internet, and distributed storage might enable reduced system generation costs. Generators and FES makers would have to cooperate to make this feasible. Now, the central techno-economic challenge is to build a high-power, low-loss motor generator that reaches full power in a very short time.

A novel minimum cost maximum power algorithm for future smart home energy management.

PubMed

Singaravelan, A; Kowsalya, M

2017-11-01

With the latest development of smart grid technology, the energy management system can be efficiently implemented at consumer premises. In this paper, an energy management system with wireless communication and smart meter are designed for scheduling the electric home appliances efficiently with an aim of reducing the cost and peak demand. For an efficient scheduling scheme, the appliances are classified into two types: uninterruptible and interruptible appliances. The problem formulation was constructed based on the practical constraints that make the proposed algorithm cope up with the real-time situation. The formulated problem was identified as Mixed Integer Linear Programming (MILP) problem, so this problem was solved by a step-wise approach. This paper proposes a novel Minimum Cost Maximum Power (MCMP) algorithm to solve the formulated problem. The proposed algorithm was simulated with input data available in the existing method. For validating the proposed MCMP algorithm, results were compared with the existing method. The compared results prove that the proposed algorithm efficiently reduces the consumer electricity consumption cost and peak demand to optimum level with 100% task completion without sacrificing the consumer comfort.

Performance Analysis of Solar-Wind-Diesel-Battery Hybrid Energy System for KLIA Sepang Station of Malaysia

NASA Astrophysics Data System (ADS)

Shezan, S. K. A.; Saidur, R.; Hossain, A.; Chong, W. T.; Kibria, M. A.

2015-09-01

A large number of populations of the world live in rural or remote areas those are geographically isolated. Power supply and uninterrupted fuel transportation to produce electrical power for these remote areas poses a great challenge. Using renewable energy in hybrid energy system might be a pathway to solve this problem. Malaysia is a large hilly land with the gift of renewable energy resources. There is a good chance to utilize these renewable resources to produce electrical power and to limit the dependency on the fossil fuel as well as reduce the carbon emissions. In this perspective, a research is carried out to analyze the performance of a solar-wind-diesel-battery hybrid energy system for a remote area named “KLIA Sepang station” in the state of Selangor, Malaysia. In this study, a 56 kW hybrid energy system has been proposed that is capable to support more than 50 households and 6 shops in that area. Real time field data of solar radiation and wind speed is used for the simulation and optimization of operations using “Homer” renewable energy software. The proposed system can reduce CO2 emission by about 16 tons per year compared to diesel generator only. In the same time the Cost of energy (COE) of the optimized system is USD 5.126/kWh.The proposed hybrid energy system might be applicable for other parts of the world where the climate conditions are similar.

Long periods with uninterrupted muscle activity related to neck and shoulder pain.

PubMed

Hanvold, Therese N; Wærsted, Morten; Veiersted, Kaj Bo

2012-01-01

The aim was to analyze the relationship between periods with uninterrupted neck muscle activity for ≥ 4 min and neck and shoulder pain. The trapezius muscle activity was recorded bilaterally on 40 young workers and students during a full shift. Neck and shoulder pain, mechanical work load and decision control were reported at the same time as the muscle activity recording and 6 months later. A dose-response relationship was found between uninterrupted muscle activity and neck and shoulder pain, with a ten-fold higher risk for the group with more than half, compared to less than a third, of the shift with uninterrupted muscle activity. Self-reported mechanical work load showed a small but protective effect related to pain. Gender and decision control did not emerge as important risk factors in this model. In conclusion, this study indicates that work or other exposures that contains long periods with uninterrupted neck muscle activity of 4 min duration or longer should be minimized to reduce risk of neck and shoulder pain.

Design and Simulation of Control Technique for Permanent Magnet Synchronous Motor Using Space Vector Pulse Width Modulation

NASA Astrophysics Data System (ADS)

Khan, Mansoor; Yong, Wang; Mustafa, Ehtasham

2017-07-01

After the rapid advancement in the field of power electronics devices and drives for last few decades, there are different kinds of Pulse Width Modulation techniques which have been brought to the market. The applications ranging from industrial appliances to military equipment including the home appliances. The vey common application for the PWM is three phase voltage source inverter, which is used to convert DC to AC in the homes to supply the power to the house in case electricity failure, usually named as Un-interrupted Power Supply. In this paper Space Vector Pulse Width Modulation techniques is discussed and analysed under the control technique named as Field Oriented Control. The working and implementation of this technique has been studied by implementing on the three phase bridge inverter. The technique is used to control the Permanente Magnet Synchronous Motor. The drive system is successfully implemented in MATLAB/Simulink using the mathematical equation and algorithm to achieve the satisfactory results. PI type of controller is used to tuned ers of the motothe parametr i.e. torque and current.

Definition study for an extended manned test of a regenerative life support system, preliminary test plan

NASA Technical Reports Server (NTRS)

1971-01-01

A preliminary plan and procedure are presented for conducting an extended manned test program for a regenerative life support system. Emphasis will be placed on elements associated with long-term system operation and long-term uninterrupted crew confinement.

Emergency and backup power supplies at Department of Energy facilities: Augmented Evaluation Team -- Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This report documents the results of the Defense Programs (DP) Augmented Evaluation Team (AET) review of emergency and backup power supplies (i.e., generator, uninterruptible power supply, and battery systems) at DP facilities. The review was conducted in response to concerns expressed by former Secretary of Energy James D. Watkins over the number of incidents where backup power sources failed to provide electrical power during tests or actual demands. The AET conducted a series of on-site reviews for the purpose of understanding the design, operation, maintenance, and safety significance of emergency and backup power (E&BP) supplies. The AET found that themore » quality of programs related to maintenance of backup power systems varies greatly among the sites visited, and often among facilities at the same site. No major safety issues were identified. However, there are areas where the AET believes the reliability of emergency and backup power systems can and should be improved. Recommendations for improving the performance of E&BP systems are provided in this report. The report also discusses progress made by Management and Operating (M&O) contractors to improve the reliability of backup sources used in safety significant applications. One area that requires further attention is the analysis and understanding of the safety implications of backup power equipment. This understanding is needed for proper graded-approach implementation of Department of Energy (DOE) Orders, and to help ensure that equipment important to the safety of DOE workers, the public, and the environment is identified, classified, recognized, and treated as such by designers, users, and maintainers. Another area considered important for improving E&BP system performance is the assignment of overall ownership responsibility and authority for ensuring that E&BP equipment performs adequately and that reliability and availability are maintained at acceptable levels.« less

Is it possible to design a portable power generator based on micro-solid oxide fuel cells? A finite volume analysis

NASA Astrophysics Data System (ADS)

Pla, D.; Sánchez-González, A.; Garbayo, I.; Salleras, M.; Morata, A.; Tarancón, A.

2015-10-01

The inherent limited capacity of current battery technology is not sufficient for covering the increasing power requirements of widely extended portable devices. Among other promising alternatives, recent advances in the field of micro-Solid Oxide Fuel Cells (μ-SOFCs) converted this disruptive technology into a serious candidate to power next generations of portable devices. However, the implementation of single cells in real devices, i.e. μ-SOFC stacks coupled to the required balance-of-plant elements like fuel reformers or post combustors, still remains unexplored. This work aims addressing this system-level research by proposing a new compact design of a vertically stacked device fuelled with ethanol. The feasibility and design optimization for achieving a thermally self-sustained regime and a rapid and low-power consuming start-up is studied by finite volume analysis. An optimal thermal insulation strategy is defined to maintain the steady-state operation temperature of the μ-SOFC at 973 K and an external temperature lower than 323 K. A hybrid start-up procedure, based on heaters embedded in the μ-SOFCs and heat released by chemical reactions in the post-combustion unit, is analyzed allowing start-up times below 1 min and energy consumption under 500 J. These results clearly demonstrate the feasibility of high temperature μ-SOFC power systems fuelled with hydrocarbons for portable applications, therefore, anticipating a new family of mobile and uninterrupted power generators.

41 CFR 101-39.303 - Maintenance.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Maintenance. 101-39.303 Section 101-39.303 Public Contracts and Property Management Federal Property Management Regulations System... Maintenance. In order to ensure uninterrupted operation of GSA Interagency Fleet Management System (IFMS...

Mission to Malapert

NASA Astrophysics Data System (ADS)

Otten, N. D.; Amoroso, E.; Jones, H. L.; Kitchell, F.; Wettergreen, D. S.; Whittaker, W. L.

2016-11-01

This work presents methodology for evaluating lunar landing site amenability and identifies promising sites for landing on Malapert Mountain, which features shallow slopes, uninterrupted Earth visibility, and ten-plus days of uninterrupted sunlight.

A distributed control approach for power and energy management in a notional shipboard power system

NASA Astrophysics Data System (ADS)

Shen, Qunying

The main goal of this thesis is to present a power control module (PCON) based approach for power and energy management and to examine its control capability in shipboard power system (SPS). The proposed control scheme is implemented in a notional medium voltage direct current (MVDC) integrated power system (IPS) for electric ship. To realize the control functions such as ship mode selection, generator launch schedule, blackout monitoring, and fault ride-through, a PCON based distributed power and energy management system (PEMS) is developed. The control scheme is proposed as two-layer hierarchical architecture with system level on the top as the supervisory control and zonal level on the bottom as the decentralized control, which is based on the zonal distribution characteristic of the notional MVDC IPS that was proposed as one of the approaches for Next Generation Integrated Power System (NGIPS) by Norbert Doerry. Several types of modules with different functionalities are used to derive the control scheme in detail for the notional MVDC IPS. Those modules include the power generation module (PGM) that controls the function of generators, the power conversion module (PCM) that controls the functions of DC/DC or DC/AC converters, etc. Among them, the power control module (PCON) plays a critical role in the PEMS. It is the core of the control process. PCONs in the PEMS interact with all the other modules, such as power propulsion module (PPM), energy storage module (ESM), load shedding module (LSHED), and human machine interface (HMI) to realize the control algorithm in PEMS. The proposed control scheme is implemented in real time using the real time digital simulator (RTDS) to verify its validity. To achieve this, a system level energy storage module (SESM) and a zonal level energy storage module (ZESM) are developed in RTDS to cooperate with PCONs to realize the control functionalities. In addition, a load shedding module which takes into account the reliability of power supply (in terms of quality of service) is developed. This module can supply uninterruptible power to the mission critical loads. In addition, a multi-agent system (MAS) based framework is proposed to implement the PCON based PEMS through a hardware setup that is composed of MAMBA boards and FPGA interface. Agents are implemented using Java Agent DEvelopment Framework (JADE). Various test scenarios were tested to validate the approach.

14 CFR 117.25 - Rest period.

Code of Federal Regulations, 2013 CFR

2013-01-01

... minimum of 8 uninterrupted hours of sleep opportunity. (f) If a flightcrew member determines that a rest period under paragraph (e) of this section will not provide eight uninterrupted hours of sleep...

Review of magnetostrictive vibration energy harvesters

NASA Astrophysics Data System (ADS)

Deng, Zhangxian; Dapino, Marcelo J.

2017-10-01

The field of energy harvesting has grown concurrently with the rapid development of portable and wireless electronics in which reliable and long-lasting power sources are required. Electrochemical batteries have a limited lifespan and require periodic recharging. In contrast, vibration energy harvesters can supply uninterrupted power by scavenging useful electrical energy from ambient structural vibrations. This article reviews the current state of vibration energy harvesters based on magnetostrictive materials, especially Terfenol-D and Galfenol. Existing magnetostrictive harvester designs are compared in terms of various performance metrics. Advanced techniques that can reduce device size and improve performance are presented. Models for magnetostrictive devices are summarized to guide future harvester designs.

1. VIEW, LOOKING NORTH, OF THE SOUTH ELEVATION OF BUILDING ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. VIEW, LOOKING NORTH, OF THE SOUTH ELEVATION OF BUILDING 901. BUILDING 901 IS ONE OF FOUR GUARD TOWERS INSTALLED AS PART OF THE PERIMETER SECURITY ZONE TO PROVIDE PROTECTIVE FORCE PERSONNEL WITH A CLEAR HIGH VIEW OF THE SURROUNDING AREAS. THE PERIMETER SECURITY ZONE CONSISTS OF A DOUBLE PERIMETER FENCE WITH CLOSED CIRCUIT TELEVISIONS, ALARMS, AND AN UNINTERRUPTED POWER SUPPLY. - Rocky Flats Plant, Guard Tower, Southeast corner of protected area, Golden, Jefferson County, CO

Clogging in constricted suspension flows

NASA Astrophysics Data System (ADS)

Marin, Alvaro; Lhuissier, Henri; Rossi, Massimiliano; Kähler, Christian J.

2018-02-01

The flow of a charged-stabilized suspension through a single constricted channel is studied experimentally by tracking the particles individually. Surprisingly, the behavior is found to be qualitatively similar to that of inertial dry granular systems: For small values of the neck-to-particle size ratio (D /d <3 ), clogs form randomly as arches of the particle span the constriction. The statistics of the clogging events are Poissonian as reported for granular systems and agree for moderate particle volume fraction (ϕ ≈20 % ) with a simple stochastic model for the number of particles at the neck. For larger neck sizes (D /d >3 ), even at the largest ϕ (≈60 %) achievable in the experiments, an uninterrupted particle flow is observed, which resembles that of an hourglass. This particularly small value of D /d (≃3 ) at the transition to a practically uninterrupted flow is attributed to the low effective friction between the particles, achieved by the particle's functionalization and lubrication.

The Insider Threat Security Architecture: An Integrated, Inseparable, and Uninterrupted Self-Protection Autonomic Framework

ERIC Educational Resources Information Center

Jabbour, Ghassan

2010-01-01

The increasing proliferation of globally interconnected complex information systems has elevated the magnitude of attacks and the level of damage that they inflict on such systems. This open environment of intertwined financial, medical, defense, and other systems has attracted hackers to increase their malicious activities to cause harm or to…

A Closed Brayton Power Conversion Unit Concept for Nuclear Electric Propulsion for Deep Space Missions

NASA Astrophysics Data System (ADS)

Joyner, Claude Russell; Fowler, Bruce; Matthews, John

2003-01-01

In space, whether in a stable satellite orbit around a planetary body or traveling as a deep space exploration craft, power is just as important as the propulsion. The need for power is especially important for in-space vehicles that use Electric Propulsion. Using nuclear power with electric propulsion has the potential to provide increased payload fractions and reduced mission times to the outer planets. One of the critical engineering and design aspects of nuclear electric propulsion at required mission optimized power levels is the mechanism that is used to convert the thermal energy of the reactor to electrical power. The use of closed Brayton cycles has been studied over the past 30 or years and shown to be the optimum approach for power requirements that range from ten to hundreds of kilowatts of power. It also has been found to be scalable to higher power levels. The Closed Brayton Cycle (CBC) engine power conversion unit (PCU) is the most flexible for a wide range of power conversion needs and uses state-of-the-art, demonstrated engineering approaches. It also is in use with many commercial power plants today. The long life requirements and need for uninterrupted operation for nuclear electric propulsion demands high reliability from a CBC engine. A CBC engine design for use with a Nuclear Electric Propulsion (NEP) system has been defined based on Pratt & Whitney's data from designing long-life turbo-machines such as the Space Shuttle turbopumps and military gas turbines and the use of proven integrated control/health management systems (EHMS). An integrated CBC and EHMS design that is focused on using low-risk and proven technologies will over come many of the life-related design issues. This paper will discuss the use of a CBC engine as the power conversion unit coupled to a gas-cooled nuclear reactor and the design trends relative to its use for powering electric thrusters in the 25 kWe to 100kWe power level.

A new on-chip all-digital three-phase full-bridge dc/ac power inverter with feedforward and frequency control techniques.

PubMed

Chen, Jiann-Jong; Kung, Che-Min

2010-09-01

The communication speed between components is far from satisfactory. To achieve high speed, simple control system configuration, and low cost, a new on-chip all-digital three-phase dc/ac power inverter using feedforward and frequency control techniques is proposed. The controller of the proposed power inverter, called the shift register, consists of six-stage D-latch flip-flops with a goal of achieving low-power consumption and area efficiency. Variable frequency is achieved by controlling the clocks of the shift register. One advantage regarding the data signal (D) and the common clock (CK) is that, regardless of the phase difference between the two, all of the D-latch flip-flops are capable of delaying data by one CK period. To ensure stability, the frequency of CK must be six times higher than that of D. The operation frequency of the proposed power inverter ranges from 10 Hz to 2 MHz, and the maximum output loading current is 0.8 A. The prototype of the proposed circuit has been fabricated with TSMC 0.35 μm 2P4M CMOS processes. The total chip area is 2.333 x 1.698 mm2. The three-phase dc/ac power inverter is applicable in uninterrupted power supplies, cold cathode fluorescent lamps, and motors, because of its ability to convert the dc supply voltage into the three-phase ac power sources.

Reliability of hybrid photovoltaic DC micro-grid systems for emergency shelters and other applications

NASA Astrophysics Data System (ADS)

Dhere, Neelkanth G.; Schleith, Susan

2014-10-01

Improvement of energy efficiency in the SunSmart Schools Emergency Shelters requires new methods for optimizing the energy consumption within the shelters. One major limitation in current systems is the requirement of converting direct current (DC) power generated from the PV array into alternating current (AC) power which is distributed throughout the shelters. Oftentimes, this AC power is then converted back to DC to run certain appliances throughout the shelters resulting in a significant waste of energy due to DC to AC and then again AC to DC conversion. This paper seeks to extract the maximum value out of PV systems by directly powering essential load components within the shelters that already run on DC power without the use of an inverter and above all to make the system reliable and durable. Furthermore, additional DC applications such as LED lighting, televisions, computers and fans operated with DC brushless motors will be installed as replacements to traditional devices in order to improve efficiency and reduce energy consumption. Cost of energy storage technologies continue to decline as new technologies scale up and new incentives are put in place. This will provide a cost effective way to stabilize the energy generation of a PV system as well as to provide continuous energy during night hours. It is planned to develop a pilot program of an integrated system that can provide uninterrupted DC power to essential base load appliances (heating, cooling, lighting, etc.) at the Florida Solar Energy Center (FSEC) command center for disaster management. PV arrays are proposed to be installed on energy efficient test houses at FSEC as well as at private homes having PV arrays where the owners volunteer to participate in the program. It is also planned to monitor the performance of the PV arrays and functioning of the appliances with the aim to improve their reliability and durability. After a successful demonstration of the hybrid DC microgrid based emergency shelter together with the monitoring system, it is planned to replicate it at other schools in Florida and elsewhere to provide continuous power for essential applications, maximizing the value of PV generation systems.

Validation of a Portable Low-Power Deep Brain Stimulation Device Through Anxiolytic Effects in a Laboratory Rat Model.

PubMed

Kouzani, Abbas Z; Kale, Rajas P; Zarate-Garza, Pablo Patricio; Berk, Michael; Walder, Ken; Tye, Susannah J

2017-09-01

Deep brain stimulation (DBS) devices deliver electrical pulses to neural tissue through an electrode. To study the mechanisms and therapeutic benefits of deep brain stimulation, murine preclinical research is necessary. However, conducting naturalistic long-term, uninterrupted animal behavioral experiments can be difficult with bench-top systems. The reduction of size, weight, power consumption, and cost of DBS devices can assist the progress of this research in animal studies. A low power, low weight, miniature DBS device is presented in this paper. This device consists of electronic hardware and software components including a low-power microcontroller, an adjustable current source, an n-channel metal-oxide-semiconductor field-effect transistor, a coin-cell battery, electrode wires and a software program to operate the device. Evaluation of the performance of the device in terms of battery lifetime and device functionality through bench and in vivo tests was conducted. The bench test revealed that this device can deliver continuous stimulation current pulses of strength [Formula: see text], width [Formula: see text], and frequency 130 Hz for over 22 days. The in vivo tests demonstrated that chronic stimulation of the nucleus accumbens (NAc) with this device significantly increased psychomotor activity, together with a dramatic reduction in anxiety-like behavior in the elevated zero-maze test.

Real-time monitoring of the human alertness level

NASA Astrophysics Data System (ADS)

Alvarez, Robin; del Pozo, Francisco; Hernando, Elena; Gomez, Eduardo; Jimenez, Antonio

2003-04-01

Many accidents are associated with a driver or machine operator's alertness level. Drowsiness often develops as a result of repetitive or monotonous tasks, uninterrupted by external stimuli. In order to enhance safety levels, it would be most desirable to monitor the individual's level of attention. In this work, changes in the power spectrum of the electroencephalographic signal (EEG) are associated with the subject's level of attention. This study reports on the initial research carried out in order to answer the following important questions: (i) Does a trend exist in the shape of the power spectrum, which will indicate the state of a subject's alertness state (drowsy, relaxed or alert)? (ii) What points on the cortex are most suitable to detect drowsiness and/or high alertness? (iii) What parameters in the power spectrum are most suitable to establish a workable alertness classification in human subjects? In this work, we answer these questions and combine power spectrum estimation and artificial neural network techniques to create a non-invasive and real - time system able to classify EEG into three levels of attention: High, Relaxed and Drowsiness. The classification is made every 10 seconds o more, a suitable time span for giving an alarm signal if the individual is with insufficient level of alertness. This time span is set by the user. The system was tested on twenty subjects. High and relaxed attention levels were measured in randomise hours of the day and drowsiness attention level was measured in the morning after one night of sleep deprivation.

Fault-Tolerant Software-Defined Radio on Manycore

NASA Technical Reports Server (NTRS)

Ricketts, Scott

2015-01-01

Software-defined radio (SDR) platforms generally rely on field-programmable gate arrays (FPGAs) and digital signal processors (DSPs), but such architectures require significant software development. In addition, application demands for radiation mitigation and fault tolerance exacerbate programming challenges. MaXentric Technologies, LLC, has developed a manycore-based SDR technology that provides 100 times the throughput of conventional radiationhardened general purpose processors. Manycore systems (30-100 cores and beyond) have the potential to provide high processing performance at error rates that are equivalent to current space-deployed uniprocessor systems. MaXentric's innovation is a highly flexible radio, providing over-the-air reconfiguration; adaptability; and uninterrupted, real-time, multimode operation. The technology is also compliant with NASA's Space Telecommunications Radio System (STRS) architecture. In addition to its many uses within NASA communications, the SDR can also serve as a highly programmable research-stage prototyping device for new waveforms and other communications technologies. It can also support noncommunication codes on its multicore processor, collocated with the communications workload-reducing the size, weight, and power of the overall system by aggregating processing jobs to a single board computer.

Technologies for the Comprehensive Exploitation of the Geothermal Resources of the North Caucasus Region

NASA Astrophysics Data System (ADS)

Alkhasov, A. B.

2018-03-01

Technology for the integrated development of low-temperature geothermal resources using the thermal and water potentials for various purposes is proposed. The heat of the thermal waters is utilized in a low-temperature district heating system and for heating the water in a hot water supply system. The water cooled in heat exchangers enters a chemical treatment system where it is conditioned into potable water quality and then forwarded to the household and potable water supply system. Efficient technologies for removal of arsenic and organic contaminants from the water have been developed. For the uninterrupted supply of the consumers with power, the technologies that use two and more types of renewable energy sources (RESs) have the best prospects. Technology for processing organic waste using the geothermal energy has been proposed. According to this technology, the geothermal water is divided into two flows, one of which is delivered to a biomass conversion system and the other is directed to a geothermal steam-gas power plant (GSGP). The wastewater arrives at the pump station from which it is pumped back into the bed. Upon drying, the biogas from the conversion system is delivered into the combustion chamber of a gas-turbine plant (GTP). The heat of the turbine exhaust gases is used in the GSGP to evaporate and reheat the low-boiling working medium. The working medium is heated in the GSGP to the evaporation temperature using the heat of the thermal water. High-temperature geothermal brines are the most promising for the comprehensive processing. According to the proposed technology, the heat energy of the brines is utilized to generate the electric power at a binary geothermal power station; the electric power is then used to extract the dissolved chemical components from the rest of the brine. The comprehensive utilization of high-temperature brines of the East-Precaucasian Artesian Basin will allow to completely satisfy the demand of Russia for lithium carbonate and sodium chloride.

Catheter ablation for atrial fibrillation on uninterrupted direct oral anticoagulants: A safe approach.

PubMed

Sawhney, V; Shaukat, M; Volkova, E; Jones, N; Providencia, R; Honarbakhsh, S; Dhillon, G; Chow, A; Lowe, M; Lambiase, P; Dhinoja, M; Sporton, S; Earley, M J; Schilling, R J; Hunter, R J

2018-05-16

Current consensus guidelines suggest DOACs are interrupted peri-procedurally for catheter ablation (CA) of AF. However, this may predispose patients to thromboembolic complications. This study investigates the safety of CA for AF on uninterrupted DOACs compared to uninterrupted warfarin. Single centre, retrospective study of consecutive patients undergoing CA for AF. All patients were heparinised prior to trans-septal puncture with a target activated clotting time (ACT) of 300-350 seconds. Patients who had procedures performed on continuous DOAC were compared to those on continuous warfarin. Clinical, procedural data and complications occurring up to 3 months were analysed from a prospective registry with additional review of electronic health records. 1884 procedures were performed over 28 months: 761(609 patients) on uninterrupted warfarin and 1123(900 patients) on uninterrupted DOAC (rivaroxaban 64%, apixaban 32% and dabigatran 4%). There was no difference in the composite end point of death, thromboembolism or major bleeding complication(2.2% vs 1.4%, p = 0.20). There was no difference in the complications comprising this including tamponade, haematoma, pseudoaneurysm, transfusion(p-values 0.28, 0.13, 0.45 and 0.36). There were no strokes, TIAs or other thromboembolic complications. There was no difference between groups in the proportion of tamponades requiring reversal of oral anticoagulation, the volume of blood lost, the proportion transfused, or the proportion drained percutaneously(p-values 0.50, 0.51, 0.36, 0.38). Catheter ablation for AF can be performed safely and effectively in patients anticoagulated with DOACs and heparinised with a therapeutic ACT. There is no increased risk of peri-procedural bleeding when compared to uninterrupted warfarin. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Energy-Efficient Control with Harvesting Predictions for Solar-Powered Wireless Sensor Networks.

PubMed

Zou, Tengyue; Lin, Shouying; Feng, Qijie; Chen, Yanlian

2016-01-04

Wireless sensor networks equipped with rechargeable batteries are useful for outdoor environmental monitoring. However, the severe energy constraints of the sensor nodes present major challenges for long-term applications. To achieve sustainability, solar cells can be used to acquire energy from the environment. Unfortunately, the energy supplied by the harvesting system is generally intermittent and considerably influenced by the weather. To improve the energy efficiency and extend the lifetime of the networks, we propose algorithms for harvested energy prediction using environmental shadow detection. Thus, the sensor nodes can adjust their scheduling plans accordingly to best suit their energy production and residual battery levels. Furthermore, we introduce clustering and routing selection methods to optimize the data transmission, and a Bayesian network is used for warning notifications of bottlenecks along the path. The entire system is implemented on a real-time Texas Instruments CC2530 embedded platform, and the experimental results indicate that these mechanisms sustain the networks' activities in an uninterrupted and efficient manner.

Energy-Efficient Control with Harvesting Predictions for Solar-Powered Wireless Sensor Networks

PubMed Central

Zou, Tengyue; Lin, Shouying; Feng, Qijie; Chen, Yanlian

2016-01-01

Wireless sensor networks equipped with rechargeable batteries are useful for outdoor environmental monitoring. However, the severe energy constraints of the sensor nodes present major challenges for long-term applications. To achieve sustainability, solar cells can be used to acquire energy from the environment. Unfortunately, the energy supplied by the harvesting system is generally intermittent and considerably influenced by the weather. To improve the energy efficiency and extend the lifetime of the networks, we propose algorithms for harvested energy prediction using environmental shadow detection. Thus, the sensor nodes can adjust their scheduling plans accordingly to best suit their energy production and residual battery levels. Furthermore, we introduce clustering and routing selection methods to optimize the data transmission, and a Bayesian network is used for warning notifications of bottlenecks along the path. The entire system is implemented on a real-time Texas Instruments CC2530 embedded platform, and the experimental results indicate that these mechanisms sustain the networks’ activities in an uninterrupted and efficient manner. PMID:26742042

48 CFR 52.222-46 - Evaluation of Compensation for Professional Employees.

Code of Federal Regulations, 2013 CFR

2013-10-01

... to provide uninterrupted high-quality work. The professional compensation proposed will be considered..., uninterrupted high-quality work, and availability of required competent professional service employees. Offerors... concerned with the quality and stability of the work force to be employed on this contract. Professional...

48 CFR 52.222-46 - Evaluation of Compensation for Professional Employees.

Code of Federal Regulations, 2014 CFR

2014-10-01

... to provide uninterrupted high-quality work. The professional compensation proposed will be considered..., uninterrupted high-quality work, and availability of required competent professional service employees. Offerors... concerned with the quality and stability of the work force to be employed on this contract. Professional...

48 CFR 52.222-46 - Evaluation of Compensation for Professional Employees.

Code of Federal Regulations, 2012 CFR

2012-10-01

... to provide uninterrupted high-quality work. The professional compensation proposed will be considered..., uninterrupted high-quality work, and availability of required competent professional service employees. Offerors... concerned with the quality and stability of the work force to be employed on this contract. Professional...

Eventual Suicide in Interrupted and Uninterrupted Attempters: A Challenge to the Cry-for-Help Hypothesis.

ERIC Educational Resources Information Center

Steer, Robert A.; And Others

1988-01-01

Followed patients (N=499) hospitalized for suicide attempts (attempters) between 1970 and 1975 until 1982. Found under six percent eventually committed suicide. Found the interrupted attempters were approximately three times more likely to commit suicide than were the uninterrupted attempters. (Author/ABL)

In-line manufacture of carbon nanotubes

DOEpatents

Brambilla, Nicol Michele; Signorelli, Riccardo; Martini, Fabrizio; Corripio Luna, Oscar Enrique

2015-04-28

Mass production of carbon nanotubes (CNT) are facilitated by methods and apparatus disclosed herein. Advantageously, the methods and apparatus make use of a single production unit, and therefore provide for uninterrupted progress in a fabrication process. Embodiments of control systems for a variety of CNT production apparatus are included.

21 CFR 640.34 - Processing.

Code of Federal Regulations, 2010 CFR

2010-04-01

... STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Plasma § 640.34 Processing. (a) Plasma. Plasma shall be... collecting, processing, and storage system unless the product is to be stored as Liquid Plasma. (b) Fresh Frozen Plasma. Fresh frozen plasma shall be prepared from blood collected by a single uninterrupted...

21 CFR 640.34 - Processing.

Code of Federal Regulations, 2012 CFR

2012-04-01

... STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Plasma § 640.34 Processing. (a) Plasma. Plasma shall be... collecting, processing, and storage system unless the product is to be stored as Liquid Plasma. (b) Fresh Frozen Plasma. Fresh frozen plasma shall be prepared from blood collected by a single uninterrupted...

21 CFR 640.34 - Processing.

Code of Federal Regulations, 2011 CFR

2011-04-01

... STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Plasma § 640.34 Processing. (a) Plasma. Plasma shall be... collecting, processing, and storage system unless the product is to be stored as Liquid Plasma. (b) Fresh Frozen Plasma. Fresh frozen plasma shall be prepared from blood collected by a single uninterrupted...

21 CFR 640.34 - Processing.

Code of Federal Regulations, 2013 CFR

2013-04-01

... STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Plasma § 640.34 Processing. (a) Plasma. Plasma shall be... collecting, processing, and storage system unless the product is to be stored as Liquid Plasma. (b) Fresh Frozen Plasma. Fresh frozen plasma shall be prepared from blood collected by a single uninterrupted...

21 CFR 640.34 - Processing.

Code of Federal Regulations, 2014 CFR

2014-04-01

... STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Plasma § 640.34 Processing. (a) Plasma. Plasma shall be... collecting, processing, and storage system unless the product is to be stored as Liquid Plasma. (b) Fresh Frozen Plasma. Fresh frozen plasma shall be prepared from blood collected by a single uninterrupted...

Experimental impedance investigation of an ultracapacitor at different conditions for electric vehicle applications

NASA Astrophysics Data System (ADS)

Zhang, Lei; Hu, Xiaosong; Wang, Zhenpo; Sun, Fengchun; Dorrell, David G.

2015-08-01

Ultracapacitors (UCs) are being increasingly deployed as a short-term energy storage device in various energy systems including uninterruptable power supplies, electrified vehicles, renewable energy systems, and wireless communication. They exhibit excellent power density and energy efficiency. The dynamic behavior of a UC, however, strongly depends on its impedance characteristics. In this paper, the impedance characteristics of a commercial UC are experimentally investigated through the well-adopted Electrochemical Impedance Spectroscopy (EIS) technique. The implications of the UC operating conditions (i.e., temperature and state of charge (SOC)) to the impedance are systematically examined. The results show that the impedance is highly sensitive to the temperature and SOC; and the temperature effect is more significant. In particular, the coupling effect between the temperature and SOC is illustrated, as well as the high-efficiency SOC window, which is highlighted. To further verify the reliability of the EIS-based investigation and to probe the sensitivity of UC parameters to the operating conditions, a dynamic model is characterized by fitting the collected impedance data. The interdependence of UC parameters (i.e., capacitance and resistance elements) on the temperature and SOC is quantitatively revealed. The impedance-based model is demonstrated to be accurate in two driving-cycle tests.

Visual method for detecting critical damage in railway contact strips

NASA Astrophysics Data System (ADS)

Judek, S.; Skibicki, J.

2018-05-01

Ensuring an uninterrupted supply of power in the electric traction is vital for the safety of this important transport system. For this purpose, monitoring and diagnostics of the technical condition of the vehicle’s power supply elements are becoming increasingly common. This paper presents a new visual method for detecting contact strip damage, based on measurement and analysis of the movement of the overhead contact line (OCL) wire. A measurement system configuration with a 2D camera was proposed. The experimental method has shown that contact strips damage can be detected by transverse displacement signal analysis. It has been proven that the velocity signal numerically established on that basis has a comparable level in the case of identical damage, regardless of its location on the surface of the contact strip. The proposed method belongs to the group of contact-less measurements, so it does not require interference with the structure of the catenary network nor the mounting of sensors in its vicinity. Measurement of displacements of the contact wire in 2D space makes it possible to combine the functions of existing diagnostic stands assessing the correctness of the mean contact force control adjustment of the current collector with the elements of the contact strip diagnostics, which involves detecting their damage which may result in overhead contact line rupture.

The application of NAVSTAR Differential GPS to civil helicopter operations

NASA Technical Reports Server (NTRS)

Beser, J.; Parkinson, B. W.

1981-01-01

Principles concerning the operation of the NAVSTAR Global Positioning Systems (GPS) are discussed. Selective availability issues concerning NAVSTAR GPS and differential GPS concepts are analyzed. Civil support and market potential for differential GPS are outlined. It is concluded that differential GPS provides a variation on the baseline GPS system, and gives an assured, uninterrupted level of accuracy for the civilian community.

Interlayer toughening of fiber composite flywheel rotors

DOEpatents

Groves, Scott E.; Deteresa, Steven J.

1998-01-01

An interlayer toughening mechanism to mitigate the growth of damage in fiber composite flywheel rotors for long application. The interlayer toughening mechanism may comprise one or more tough layers composed of high-elongation fibers, high-strength fibers arranged in a woven pattern at a range from 0.degree. to 90.degree. to the rotor axis and bound by a ductile matrix material which adheres to and is compatible with the materials used for the bulk of the rotor. The number and spacing of the tough interlayers is a function of the design requirements and expected lifetime of the rotor. The mechanism has particular application in uninterruptable power supplies, electrical power grid reservoirs, and compulsators for electric guns, as well as electromechanical batteries for vehicles.

Interlayer toughening of fiber composite flywheel rotors

DOEpatents

Groves, S.E.; Deteresa, S.J.

1998-07-14

An interlayer toughening mechanism is described to mitigate the growth of damage in fiber composite flywheel rotors for long application. The interlayer toughening mechanism may comprise one or more tough layers composed of high-elongation fibers, high-strength fibers arranged in a woven pattern at a range from 0{degree} to 90{degree} to the rotor axis and bound by a ductile matrix material which adheres to and is compatible with the materials used for the bulk of the rotor. The number and spacing of the tough interlayers is a function of the design requirements and expected lifetime of the rotor. The mechanism has particular application in uninterruptable power supplies, electrical power grid reservoirs, and compulsators for electric guns, as well as electromechanical batteries for vehicles. 2 figs.

An Introduced Hybrid Graphene/Polyaniline Composites for Improvement of Supercapacitor

NASA Astrophysics Data System (ADS)

Tayel, Mazhar B.; Soliman, Moataz M.; Ebrahim, Shaker; Harb, Mohamed E.

2016-01-01

Supercapacitors represent an attractive alternative for portable electronics and automotive applications due to their high capacitance, specific power and extended life. In fact, the growing demand of portable systems and hybrid electric vehicles, memory protection in complementary metal-oxide-semiconductor (CMOS), logic circuit, videocassette recorders (VCRs), compact disc (CD) players, personal computers (PCs), uninterruptible power supply (UPS) in security alarm systems, remote sensing, smoke detectors, etc. require high power in short-term pulses. Therefore, in the last 20 years, supercapacitors have been required for the development of large and small devices driven by electrical power. In this paper, graphene oxide (GO) was synthesized by improved Hummers method. Two polyaniline (PANI)/graphene oxide nanocomposites electrode materials were prepared from aniline, GO and ammoniumpersulfate (APS) by in situ chemical polymerization with the mass ratios (mGO:mAniline) 10:90 and 30: 70 in ice bath. The crystal structure and the surface topography of all materials were characterized by means of x-ray diffraction (XRD), Fourier transform infrared spectrum (FTIR), Raman spectroscopy and scanning electron microscopy (SEM). The electrochemical properties of the composites were evaluated by cyclic voltammetry (CV), charge-discharge measurements and electrical impedance spectroscopy (EIS), respectively. The results show that the composites have similar and enhanced cyclic voltammetry performance compared with pure PANI based electrode material. The graphene/PANI composite synthesized with the mass ratio (mANI:mGO) 90:10 possessed good capacitive behavior with a specific capacitance as high as 1509.35 F/g at scan rate of 1 mV/s in scanning potential window from -0.8 V to 0.8 V.

Safety and Efficacy of Uninterrupted Apixaban Therapy Versus Warfarin During Atrial Fibrillation Ablation.

PubMed

Shah, Ruchit R; Pillai, Ajay; Schafer, Pascha; Meggo, David; McElderry, Tom; Plumb, Vance; Yamada, Takumi; Kumar, Vineet; Doppalapudi, Harish; Gunter, Alicia; Pentecost, Emily; Maddox, William R

2017-08-01

Thromboembolic cerebrovascular accident remains a rare but potentially devastating complication of catheter-based atrial fibrillation (AF) ablation. Uninterrupted oral anticoagulant therapy with warfarin has become the standard of care when performing catheter-based AF ablation. Compared with warfarin, apixaban, a factor Xa inhibitor, has been shown to reduce the risk of stroke and major bleeding in nonvalvular AF. With an increase in apixaban use for stroke prophylaxis in patients with AF, there is an increased interest in the safety and efficacy of uninterrupted apixaban therapy during AF ablation. We compared the safety and efficacy of uninterrupted OA therapy with either warfarin or apixaban in all patients who underwent catheter-based AF ablation at the University of Alabama at Birmingham and at Augusta University Medical Center from January 7, 2013, to February 25, 2016. All patients underwent a transesophageal echocardiogram on the day of their ablation to assess for the presence of intracardiac thrombi. All complications were identified and classified as bleeding, thromboembolic events, or other. A total of 627 patients were analyzed as described earlier. There were 310 patients in the warfarin group and 317 patients in the apixaban group. There were 8 complications in the warfarin group and 5 complications in the apixaban group (p = 0.38). There were no thromboembolic complications in either group. In conclusion, the use of apixaban is as safe and effective as warfarin for uninterrupted OA therapy during catheter-based ablation of AF. Copyright © 2017 Elsevier Inc. All rights reserved.

Buffering PV output during cloud transients with energy storage

NASA Astrophysics Data System (ADS)

Moumouni, Yacouba

Consideration of the use of the major types of energy storage is attempted in this thesis in order to mitigate the effects of power output transients associated with grid-tied CPV systems due to fast-moving cloud coverage. The approach presented here is to buffer intermittency of CPV output power with an energy storage device (used batteries) purchased cheaply from EV owners or battery leasers. When the CPV is connected to the grid with the proper energy storage, the main goal is to smooth out the intermittent solar power and fluctuant load of the grid with a convenient control strategy. This thesis provides a detailed analysis with appropriate Matlab codes to put onto the grid during the day time a constant amount of power on one hand and on the other, shift the less valuable off-peak electricity to the on-peak time, i.e. between 1pm to 7pm, where the electricity price is much better. In this study, a range of base constant power levels were assumed including 15kW, 20kW, 21kW, 22kW, 23kW, 24kW and 25kW. The hypothesis based on an iterative solution was that the capacity of the battery was increased by steps of 5 while the base supply was decreased by the same step size until satisfactorily results were achieved. Hence, it turned out with the chosen battery capacity of 54kWh coupled to the data from the Amonix CPV 7700 unit for Las Vegas for a 3-month period, it was found that 20kW was the largest constant load the system can supply uninterruptedly to the utility company. Simulated results are presented to show the feasibility of the proposed scheme.

Effects of breaking up sitting on adolescents' postprandial glucose after consuming meals varying in energy: a cross-over randomised trial.

PubMed

Fletcher, Elly A; Salmon, Jo; McNaughton, Sarah A; Orellana, Liliana; Wadley, Glenn D; Bruce, Clinton; Dempsey, Paddy C; Lacy, Kathleen E; Dunstan, David W

2018-03-01

To explore the impact of uninterrupted sitting versus sitting with resistance-type activity breaks on adolescents' postprandial glucose responses while consuming a diet varying in energy. Cross-over randomised trial. Thirteen healthy participants (16.4±1.3years) completed a four-treatment cross-over trial: (1) uninterrupted sitting+high-energy diet; (2) sitting with breaks+high-energy diet; (3) uninterrupted sitting+standard-energy diet; and (4) sitting with breaks+standard-energy diet. For all four conditions, two identical meals were consumed; at 0h and 3h. A continuous glucose monitoring system (CGM) recorded interstitial glucose concentrations every five minutes. Linear mixed models examined differences in glucose positive incremental area under the curve (iAUC) and total AUC between the sitting and diet conditions for the first meal, second meal and entire trial period. Compared to the uninterrupted sitting conditions, the breaks condition elicited a 36.0mmol/L/h (95%CI 6.6-65.5) and 35.9mmol/L/h (95%CI 6.6-65.5) lower iAUC response after the first and second meal, respectively, but not for the entire trial period or for total AUC. Compared to the standard-energy diet, the high-energy diet elicited a 55.0mmol/L/h (95%CI 25.8-84.2) and 75.7mmol/L/h (95%CI 8.6-142.7) higher iAUC response after the first meal and entire trial, respectively. Similar response to the high-energy diet were observed for total AUC. According to iAUC, interrupting sitting had a significant effect on lowering postprandial glucose for both dietary conditions, however, it was not significant when examining total AUC. Larger studies are needed to confirm these findings. ACTRN12615001145594. Copyright © 2017 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

Hydrogen-Oxygen PEM Regenerative Fuel Cell Development at the NASA Glenn Research Center

NASA Technical Reports Server (NTRS)

Bents, David J.; Scullin, Vincent J.; Chang, Bei-Jiann; Johnson, Donald W.; Garcia, Christoher P.; Jakupca, Ian J.

2005-01-01

The closed-cycle hydrogen-oxygen PEM regenerative fuel cell (RFC) at the NASA Glenn Research Center has successfully demonstrated closed cycle operation at rated power for multiple charge-discharge cycles. During charge cycle the RFC has absorbed input electrical power simulating a solar day cycle ranging from zero to 15 kWe peak, and delivered steady 5 kWe output power for periods exceeding 8 hr. Orderly transitions from charge to discharge mode, and return to charging after full discharge, have been accomplished without incident. Continuing test operations focus on: (1) Increasing the number of contiguous uninterrupted charge discharge cycles; (2) Increasing the performance envelope boundaries; (3) Operating the RFC as an energy storage device on a regular basis; (4) Gaining operational experience leading to development of fully automated operation; and (5) Developing instrumentation and in situ fluid sampling strategies to monitor health and anticipate breakdowns.

Seasonal energy storage system based on hydrogen for self sufficient living

NASA Astrophysics Data System (ADS)

Bielmann, M.; Vogt, U. F.; Zimmermann, M.; Züttel, A.

SELF is a resource independent living and working environment. By on-board renewable electricity generation and storage, it accounts for all aspects of living, such as space heating and cooking as well as providing a purified rainwater supply and wastewater treatment, excluding food supply. Uninterrupted, on-demand energy and water supply are the key challenges. Off-grid renewable power supply fluctuations on daily and seasonal time scales impose production gaps that have to be served by local storage, a function normally fulfilled by the grid. While daily variations only obligate a small storage capacity, requirements for seasonal storage are substantial. The energy supply for SELF is reviewed based on real meteorological data and demand patterns for Zurich, Switzerland. A battery system with propane for cooking serves as a reference for battery-only and hybrid battery/hydrogen systems. In the latter, hydrogen is used for cooking and electricity generation. The analysis shows that hydrogen is ideal for long term bulk energy storage on a seasonal timescale, while batteries are best suited for short term energy storage. Although the efficiency penalty from hydrogen generation is substantial, in off-grid systems, this parameter is tolerable since the harvesting ratio of photovoltaic energy is limited by storage capacity.

Creep Strength of Nb-1Zr for SP-100 Applications

NASA Astrophysics Data System (ADS)

Horak, James A.; Egner, Larry K.

1994-07-01

Power systems that are used to provide electrical power in space are designed to optimize conversion of thermal energy to electrical energy and to minimize the mass and volume that must be launched. Only refractory metals and their alloys have sufficient long-term strength for several years of uninterrupted operation at the required temperatures of 1200 K and above. The high power densities and temperatures at which these reactors must operate require the use of liquid-metal coolants. The alloy Nb-1 wt % Zr (Nb-lZr), which exhibits excellent corrosion resistance to alkali liquid-metals at high temperatures, is being considered for the fuel cladding, reactor structural, and heat-transport systems for the SP-100 reactor system. Useful lifetime of this system is limited by creep deformation in the reactor core. Nb-lZr sheet procured to American Society for Testing and Materials (ASTM) specifications for reactor grade and commercial grade has been processed by several different cold work and annealing treatments to attempt to produce the grain structure (size, shape, and distribution of sizes) that provides the maximum creep strength of this alloy at temperatures from 1250 to 1450 K. The effects of grain size, differences in oxygen concentrations, tungsten concentrations, and electron beam and gas tungsten arc weldments on creep strength were studied. Grain size has a large effect on creep strength at 1450 K but only material with a very large grain size (150 μm) exhibits significantly higher creep strength at 1350 K. Differences in oxygen or tungsten concentrations did not affect creep strength, and the creep strengths of weldments were equal to, or greater than, those for base metal.

Design and control of a novel two-speed Uninterrupted Mechanical Transmission for electric vehicles

NASA Astrophysics Data System (ADS)

Fang, Shengnan; Song, Jian; Song, Haijun; Tai, Yuzhuo; Li, Fei; Sinh Nguyen, Truong

2016-06-01

Conventional all-electric vehicles (EV) adopt single-speed transmission due to its low cost and simple construction. However, with the adoption of this type of driveline system, development of EV technology leads to the growing performance requirements of drive motor. Introducing a multi-speed or two-speed transmission to EV offers the possibility of efficiency improvement of the whole powertrain. This paper presents an innovative two-speed Uninterrupted Mechanical Transmission (UMT), which consists of an epicyclic gearing system, a centrifugal clutch and a brake band, allowing the seamless shifting between two gears. Besides, driver's intention is recognized by the control system which is based on fuzzy logic controller (FLC), utilizing the signals of vehicle velocity and accelerator pedal position. The novel UMT shows better dynamic and comfort performance in compare with the optimized AMT with the same gear ratios. Comparison between the control strategy with recognition of driver intention and the conventional two-parameter gear shifting strategy is presented. And the simulation and analysis of the middle layer of optimal gearshift control algorithm is detailed. The results indicate that the UMT adopting FLC and optimal control method provides a significant improvement of energy efficiency, dynamic performance and shifting comfort for EV.

Prolonged sitting and markers of cardiometabolic disease risk in children and youth: a randomized crossover study.

PubMed

Saunders, Travis J; Chaput, Jean-Philippe; Goldfield, Gary S; Colley, Rachel C; Kenny, Glen P; Doucet, Eric; Tremblay, Mark S

2013-10-01

Recent evidence suggests that short bouts of uninterrupted sedentary behavior reduce insulin sensitivity and glucose tolerance while increasing triglyceride levels in both healthy and overweight/obese adults. To date no study has examined the acute impact of uninterrupted sitting in children and youth. The objective of the present study was to determine whether 8 h of uninterrupted sitting increases markers of cardiometabolic disease risk in healthy children and youth, in comparison to 8 h of sitting interrupted by light intensity walk breaks or structured physical activity. 11 healthy males and 8 healthy females between the ages of 10 and 14 years experienced 3 conditions in random order: (1) 8 h of uninterrupted sitting (Sedentary); (2) 8 h of sitting interrupted with a 2-min light-intensity walk break every 20 min (Breaks); and (3) 8 h of sitting interrupted with a 2-min light-intensity walk break every 20 min as well as 2×20 min of moderate-intensity physical activity (Breaks+Physical Activity). Insulin, glucose, triglyceride, HDL and LDL cholesterol area under the curve were calculated for each condition. We observed no significant differences in the area under the curve for any marker of cardiometabolic disease risk across the 3 study conditions (all p>0.09). These results suggest that in comparison to interrupted sitting or structured physical activity, a single bout of 8 h of uninterrupted sitting does not result in measurable changes in circulating levels of insulin, glucose, or lipids in healthy children and youth. Copyright © 2013 Elsevier Inc. All rights reserved.

Magnetostrictive patch sensor system for battery-less real-time measurement of torsional vibrations of rotating shafts

NASA Astrophysics Data System (ADS)

Lee, Jun Kyu; Seung, Hong Min; Park, Chung Il; Lee, Joo Kyung; Lim, Do Hyeong; Kim, Yoon Young

2018-02-01

Real-time uninterrupted measurement for torsional vibrations of rotating shafts is crucial for permanent health monitoring. So far, strain gauge systems with telemetry units have been used for real-time monitoring. However, they have a critical disadvantage in that shaft operations must be stopped intermittently to replace telemetry unit batteries. To find an alternative method to carry out battery-less real-time measurement for torsional vibrations of rotating shafts, a magnetostrictive patch sensor system was proposed in the present study. Since the proposed sensor does not use any powered telemetry system, no battery is needed and thus there is no need to stop rotating shafts for battery replacement. The proposed sensor consists of magnetostrictive patches and small magnets tightly bonded onto a shaft. A solenoid coil is placed around the shaft to convert magnetostrictive patch deformation by shaft torsional vibration into electric voltage output. For sensor design and characterization, investigations were performed in a laboratory on relatively small-sized stationary solid shaft. A magnetostrictive patch sensor system was then designed and installed on a large rotating propulsion shaft of an LPG carrier ship in operation. Vibration signals were measured using the proposed sensor system and compared to those measured with a telemetry unit-equipped strain gauge system.

IN2 Profile: Go Electric Provides Grid Stabilizing Energy Service Solutions to Utilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pless, Shanti

Through the Wells Fargo Innovation Incubator (IN²) program, Go Electric will validate their Link DR technology, which is an advanced, uninterruptable power supply that provides secure power, lowers facility energy costs, integrates renewables, and generates income from utility demand response programs. The IN² program launched in October 2014 and is part of Wells Fargo’s 2020 Environmental Commitment to provide $100 million to environmentally-focused nonprofits and universities. The goal is to create an ecosystem that fosters and accelerates the commercialization of promising commercial buildings technologies that can provide scalable solutions to reduce the energy impact of buildings. According to the Departmentmore » of Energy, nearly 40 percent of energy consumption in the U.S. today comes from buildings at an estimated cost of $413 billion.« less

A Wide-field Camera and Fully Remote Operations at the Wyoming Infrared Observatory

NASA Astrophysics Data System (ADS)

Findlay, Joseph R.; Kobulnicky, Henry A.; Weger, James S.; Bucher, Gerald A.; Perry, Marvin C.; Myers, Adam D.; Pierce, Michael J.; Vogel, Conrad

2016-11-01

Upgrades at the 2.3 meter Wyoming Infrared Observatory telescope have provided the capability for fully remote operations by a single operator from the University of Wyoming campus. A line-of-sight 300 Megabit s-1 11 GHz radio link provides high-speed internet for data transfer and remote operations that include several realtime video feeds. Uninterruptable power is ensured by a 10 kVA battery supply for critical systems and a 55 kW autostart diesel generator capable of running the entire observatory for up to a week. The construction of a new four-element prime-focus corrector with fused-silica elements allows imaging over a 40‧ field of view with a new 40962 UV-sensitive prime-focus camera and filter wheel. A new telescope control system facilitates the remote operations model and provides 20″ rms pointing over the usable sky. Taken together, these improvements pave the way for a new generation of sky surveys supporting space-based missions and flexible-cadence observations advancing emerging astrophysical priorities such as planet detection, quasar variability, and long-term time-domain campaigns.

Power Distribution at the Bottom of the Pyramid: Illumination through Affordable and Sustainable Solution of Gram Power

NASA Astrophysics Data System (ADS)

Pandey, Nisha; Sarswat, Prashant

2016-03-01

Energy plays a vital role in the socio -economic development, mainly due to the dependency of indispensable amenities on electricity. However, a matter of concern is developing country domestic power needs and inadequate supply. One of the cases is Indian subcontinent, where more than 50,000 villages still not have access to uninterrupted electric power. `Power theft' is a major challenge due to the lack of adequate energy supply and the financial constraints. Long distances, inaccurate and inflated electricity bills are the other issues lead to default on payments. Gram Power, a social enterprise, is providing a smart metering and affordable solution in areas where the extension of existing grid supply is economically not viable. India's first solar powered micro-grid (centralized array of solar panels) in Rajasthan was established by this initiative. The core innovation is a smart distribution technology that consists of smart meters with recharging facility and grid monitoring, to provide on-demand, theft-proof power through centralized servers with a pay-as-you-use schedule. The details of the changes, socio-economic transformation, and operational sustainability of such a community engagement model will be discussed in this study.

Enhanced Freight Tracking System: Increased Visibility for the Future

DTIC Science & Technology

2009-11-01

personnel queried the Enhanced Freight Tracking System ( EFTS ). The EFTS records showed that the items arrived at the port of a neighboring country two weeks...humanitarian missions to continue uninterrupted, potentially saving hundreds of lives. Because the EFTS provides precise shipment status data to mission...33 billion. In addition to materiel coming from Department of Defense (DOD) stock , the U.S. Government (USG) is procuring from domestic and

Novel insight into the origin of the growth dynamics of sauropod dinosaurs.

PubMed

Cerda, Ignacio Alejandro; Chinsamy, Anusuya; Pol, Diego; Apaldetti, Cecilia; Otero, Alejandro; Powell, Jaime Eduardo; Martínez, Ricardo Nestor

2017-01-01

Sauropod dinosaurs include the largest terrestrial animals and are considered to have uninterrupted rapid rates of growth, which differs from their more basal relatives, which have a slower cyclical growth. Here we examine the bone microstructure of several sauropodomorph dinosaurs, including basal taxa, as well as the more derived sauropods. Although our results agree that the plesiomorphic condition for Sauropodomorpha is cyclical growth dynamics, we found that the hypothesized dichotomy between the growth patterns of basal and more derived sauropodomorphs is not supported. Here, we show that sauropod-like growth dynamics of uninterrupted rapid growth also occurred in some basal sauropodomorphs, and that some basal sauropods retained the plesiomorphic cyclical growth patterns. Among the sauropodomorpha it appears that the basal taxa exploited different growth strategies, but the more derived Eusauropoda successfully utilized rapid, uninterrupted growth strategies.

Novel insight into the origin of the growth dynamics of sauropod dinosaurs

PubMed Central

Cerda, Ignacio Alejandro; Chinsamy, Anusuya; Pol, Diego; Apaldetti, Cecilia; Otero, Alejandro; Martínez, Ricardo Nestor

2017-01-01

Sauropod dinosaurs include the largest terrestrial animals and are considered to have uninterrupted rapid rates of growth, which differs from their more basal relatives, which have a slower cyclical growth. Here we examine the bone microstructure of several sauropodomorph dinosaurs, including basal taxa, as well as the more derived sauropods. Although our results agree that the plesiomorphic condition for Sauropodomorpha is cyclical growth dynamics, we found that the hypothesized dichotomy between the growth patterns of basal and more derived sauropodomorphs is not supported. Here, we show that sauropod-like growth dynamics of uninterrupted rapid growth also occurred in some basal sauropodomorphs, and that some basal sauropods retained the plesiomorphic cyclical growth patterns. Among the sauropodomorpha it appears that the basal taxa exploited different growth strategies, but the more derived Eusauropoda successfully utilized rapid, uninterrupted growth strategies. PMID:28654696

Status and Outlook for the U.S. Non-Automotive Fuel Cell Industry: Impacts of Government Policies and Assessment of Future Opportunities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greene, David L; Duleep, K. G.; Upreti, Girish

Fuel cells (FCs) are considered essential future energy technologies by developed and developing economies alike. Several countries, including the United States, Japan, Germany, and South Korea have established publicly funded R&D and market transformation programs to develop viable domestic FC industries for both automotive and non-automotive applications. Important non-automotive applications include large scale and small scale distributed combined heat and electrical power, backup and uninterruptible power, material handling and auxiliary power units. The U.S. FC industry is in the early stages of development, and is working to establish sustainable markets in all these areas. To be successful, manufacturers must reducemore » costs, improve performance, and overcome market barriers to new technologies. U.S. policies are assisting via research and development, tax credits and government-only and government-assisted procurements. Over the past three years, the industry has made remarkable progress, bringing both stack and system costs down by more than a factor of two while improving durability and efficiency, thanks in part to government support. Today, FCs are still not yet able to compete in these markets without continued policy support. However, continuation or enhancement of current policies, such as the investment tax credit and government procurements, together with continued progress by the industry, appears likely to establish a viable domestic industry within the next decade.« less

Anti-Jam GPS Antennas for Wearable Dismounted Soldier Navigation Systems

DTIC Science & Technology

2016-06-01

in this report are not to be construed as an official Department of the Army position unless so designated by other authorized documents. Citation...Approaches for the design and fabrication of a wearable anti-jam global positioning system (GPS) antenna are explored to support accurate and uninterrupted...including GPS antenna element and array designs , and algorithms for jammer mitigation, and the candidate technologies best fit for wearable anti-jam GPS

Fluid-driven reciprocating apparatus and valving for controlling same

DOEpatents

Whitehead, John C.; Toews, Hans G.

1993-01-01

A control valve assembly for alternately actuating a pair of fluid-driven free-piston devices by using fluid pressure communication therebetween. Each control valve is switched by a pressure signal depending on the state of its counterpart's piston. The communication logic is arranged to provide overlap of the forward strokes of the pistons, so that at least one of the pair will always be pressurized. Thus, uninterrupted pumping of liquid is made possible from a pair of free-piston pumps. In addition, the speed and frequency of piston stroking is entirely dependent on the mechanical power load applied. In the case of a pair of pumps, this enables liquid delivery at a substantially constant pressure over the full range of flow rates, from zero to maximum flow. One embodiment of the invention utilized two pairs of fluid-driven free-piston devices whereby a bipropellant liquid propulsion system may be operated, so as to provide continuous flow of both fuel and oxidizer liquids when used in rocket applications, for example.

Composite Flywheels Assessed Analytically by NDE and FEA

NASA Technical Reports Server (NTRS)

Abdul-Aziz, Ali; Baaklini, George Y.

2000-01-01

As an alternative to expensive and short-lived lead-acid batteries, composite flywheels are being developed to provide an uninterruptible power supply for advanced aerospace and industrial applications. Flywheels can help prevent irregularities in voltage caused by power spikes, sags, surges, burnout, and blackouts. Other applications include load-leveling systems for wind and solar power facilities, where energy output fluctuates with weather. Advanced composite materials are being considered for these components because they are significantly lighter than typical metallic alloys and have high specific strength and stiffness. However, much more research is needed before these materials can be fully utilized, because there is insufficient data concerning their fatigue characteristics and nonlinear behavior, especially at elevated temperatures. Moreover, these advanced types of structural composites pose greater challenges for nondestructive evaluation (NDE) techniques than are encountered with typical monolithic engineering metals. This is particularly true for ceramic polymer and metal matrix composites, where structural properties are tailored during the processing stages. Current efforts involving the NDE group at the NASA Glenn Research Center at Lewis Field are focused on evaluating many important structural components, including the flywheel system. Glenn's in-house analytical and experimental capabilities are being applied to analyze data produced by computed tomography (CT) scans to help assess the damage and defects of high-temperature structural composite materials. Finite element analysis (FEA) has been used extensively to model the effects of static and dynamic loading on aerospace propulsion components. This technique allows the use of complicated loading schemes by breaking the complex part geometry into many smaller, geometrically simple elements.

A control strategy for grid-side converter of DFIG under unbalanced condition based on Dig SILENT/Power Factory

NASA Astrophysics Data System (ADS)

Han, Pingping; Zhang, Haitian; Chen, Lingqi; Zhang, Xiaoan

2018-01-01

The models of doubly fed induction generator (DFIG) and its grid-side converter (GSC) are established under unbalanced grid condition based on DIgSILENT/PowerFactory. According to the mathematical model, the vector equations of positive and negative sequence voltage and current are deduced in the positive sequence synchronous rotating reference frame d-q-0 when the characteristics of the simulation software are considered adequately. Moreover, the reference value of current component of GSC in the positive sequence frame d-q-0 under unbalanced condition can be obtained to improve the traditional control of GSC when the national issue of unbalanced current limits is combined. The simulated results indicate that the control strategy can restrain negative sequence current and the two times frequency power wave of GSC’s ac side effectively. The voltage of DC bus can be maintained a constant to ensure the uninterrupted operation of DFIG under unbalanced grid condition eventually.

R&D of high reliable refrigeration system for superconducting generators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hosoya, T.; Shindo, S.; Yaguchi, H.

1996-12-31

Super-GM carries out R&D of 70 MW class superconducting generators (model machines), refrigeration system and superconducting wires to apply superconducting technology to electric power apparatuses. The helium refrigeration system for keeping field windings of superconducting generator (SCG) in cryogenic environment must meet the requirement of high reliability for uninterrupted long term operation of the SCG. In FY 1992, a high reliable conventional refrigeration system for the model machines was integrated by combining components such as compressor unit, higher temperature cold box and lower temperature cold box which were manufactured utilizing various fundamental technologies developed in early stage of the projectmore » since 1988. Since FY 1993, its performance tests have been carried out. It has been confirmed that its performance was fulfilled the development target of liquefaction capacity of 100 L/h and impurity removal in the helium gas to < 0.1 ppm. Furthermore, its operation method and performance were clarified to all different modes as how to control liquefaction rate and how to supply liquid helium from a dewar to the model machine. In addition, the authors have made performance tests and system performance analysis of oil free screw type and turbo type compressors which greatly improve reliability of conventional refrigeration systems. The operation performance and operational control method of the compressors has been clarified through the tests and analysis.« less

DS Sentry: an acquisition ASIC for smart, micro-power sensing applications

NASA Astrophysics Data System (ADS)

Liobe, John; Fiscella, Mark; Moule, Eric; Balon, Mark; Bocko, Mark; Ignjatovic, Zeljko

2011-06-01

Unattended ground monitoring that combines seismic and acoustic information can be a highly valuable tool in intelligence gathering; however there are several prerequisites for this approach to be viable. The first is high sensitivity as well as the ability to discriminate real threats from noise and other spurious signals. By combining ground sensing with acoustic and image monitoring this requirement may be achieved. Moreover, the DS Sentry®provides innate spurious signal rejection by the "active-filtering" technique employed as well as embedding some basic statistical analysis. Another primary requirement is spatial and temporal coverage. The ideal is uninterrupted, long-term monitoring of an area. Therefore, sensors should be densely deployed and consume very little power. Furthermore, sensors must be inexpensive and easily deployed to allow dense placements in critical areas. The ADVIS DS Sentry®, which is a fully-custom integrated circuit that enables smart, micro-power monitoring of dynamic signals, is the foundation of the proposed system. The core premise behind this technology is the use of an ultra-low power front-end for active monitoring of dynamic signals in conjunction with a highresolution, Σ Δ-based analog-to-digital converter, which utilizes a novel noise rejection technique and is only employed when a potential threat has been detected. The DS Sentry® can be integrated with seismic accelerometers and microphones and user-programmed to continuously monitor for signals with specific signatures such as impacts, footsteps, excavation noise, vehicle-induced ground vibrations, or speech, while consuming only microwatts of power. This will enable up to several years of continuous monitoring on a single small battery while concurrently mitigating false threats.

Validation of a classification system to grade fractionation in atrial fibrillation and correlation with automated detection systems.

PubMed

Hunter, Ross J; Diab, Ihab; Thomas, Glyn; Duncan, Edward; Abrams, Dominic; Dhinoja, Mehul; Sporton, Simon; Earley, Mark J; Schilling, Richard J

2009-12-01

We tested application of a grading system describing complex fractionated electrograms (CFE) in atrial fibrillation (AF) and used it to validate automated CFE detection (AUTO). Ten seconds bipolar electrograms were classified by visual inspection (VI) during ablation of persistent AF and the result compared with offline manual measurement (MM) by a second blinded operator: Grade 1 uninterrupted fractionated activity (defined as segments > or =70 ms) for > or =70% of recording and uninterrupted > or =1 s; Grade 2 interrupted fractionated activity > or =70% of recording; Grade 3 intermittent fractionated activity 30-70%; Grade 4 discrete (<70 ms) complex electrogram (> or =5 direction changes); Grade 5 discrete simple electrograms (< or =4 direction changes); Grade 6 scar. Grade by VI and MM for 100 electrograms agreed in 89%. Five hundred electrograms were graded on Carto and NavX by VI to validate AUTO in (i) detection of CFE (grades 1-4 considered CFE), and (ii) assessing degree of fractionation by correlating grade and score by AUTO (data shown as sensitivity, specificity, r): NavX 'CFE mean' 92%, 91%, 0.56; Carto 'interval confidence level' using factory settings 89%, 62%, -0.72, and other published settings 80%, 74%, -0.65; Carto 'shortest confidence interval' 74%, 70%, 0.43; Carto 'average confidence interval' 86%, 66%, 0.53. Grading CFE by VI is accurate and correlates with AUTO.

The Lighthouse Ocean Research Initiative: Sustained Cabled Ocean Observing Systems in the Sea of Oman and Arabian Sea

NASA Astrophysics Data System (ADS)

Ingle, S.; Du Vall, K.; Dimarco, S. F.

2011-12-01

In 2003 Lighthouse R & D Enterprises, Inc. began developing an ocean observing system that would help the Sultanate of Oman better manage the health of their fisheries. The resulting cutting-edge, fiber-optic cabled ocean observatory was installed in the northern Sea of Oman and became operational in August of 2005; this summer the system surpassed the milestone of 2100 days of successful operation. A second, deepwater cabled observatory was installed farther to the south, where the Sea of Oman meets the Arabian Sea, in January, 2010. Both systems monitor physical properties throughout the water column including current velocity, temperature, pressure, conductivity, dissolved oxygen and turbidity. The entirely subsea nature of the fiber-optic cabled observatory capitalizes on several advantages over traditional buoyed systems including a lack of exposure to environmental wear and tear, collision, vandalism and theft. The systems are both cabled to nearby shore facilities, where the data are relayed instantly to Houston via satellite for processing, analysis and modeling - the data may also be used in making real time decisions. Many challenges were encountered between the design / development stage and the operation a reliable, long-term, real-time observing system in a dynamic marine environment. Examples of obstacles we encountered and overcame include: maintaining upright mooring strings under differential current velocities; minimizing points of weakness in the system, especially the number of wet mates; recognizing the need for cathodic protection in unanticipated places; protecting vulnerable sensors from biofouling; developing a climate-controlled shore facility in a harsh and remote environment; ensuring an uninterrupted power supply and availability of additional power bursts when required; and lengthening the life of the system while reducing the need for maintenance. The design and obstacles and scientific questions being addressed by the Lighthouse systems will be covered in this presentation.

a Borehole Seismic System for Active and Passive Seimsic Studies to 3 KM at Ptrc's Aquistore Project

NASA Astrophysics Data System (ADS)

Schmitt, D. R.; Nixon, C.; Kofman, R.; White, D. J.; Worth, K.

2015-12-01

We have constructed a downhole seismic recording system for application to depths of nearly 3 km and temperatures up to 135 °C at Aquistore, an independent research and monitoring project in which liquid CO2 is being stored in a brine and sandstone water formation. The key component to this system is a set of commercially available slim-hole 3-C sondes carrying 15 Hz geophones deployable in open and cased boreholes with diameters as small as 57 mm. The system is currently hosted on a 4-conductor wireline with digital information streamed to the surface recording unit. We have further incorporated these sondes into a mobile passive monitoring unit that includes a number of redundancies such as a multiple Tbyte network accessible RAID hard-drive system (NAS) and a self-designed uninterruptible power supply. The system can be remotely controlled via the internet. The system is currently deployed covering a range of depths from 2850 m to 2910 m. Ambient temperatures at this depth are approximately 110 °C with onboard tool temperatures running at 115 °C. Data is continuously streamed to the NAS for archiving, approximately 11 GBytes of data is recorded per day at the sampling period of 0.5 ms. The lack of noise at this depth allows short data snippets to be flagged with a simple amplitude threshold criteria. The greatly reduced data volume of the snippets allows for ready access via the internet to the system for ongoing quality control. Spurious events, mostly small amplitude tube waves originating at or near the surface, are readily discounted. Active seismic measurements are carried out simultaneously but these require that an appropriately accurate independent GPS based time synchronization be used. Various experiences with event detection, orientation of sondes using both explosives and seismic vibrator, potential overheating of the surface electronics, and issues related to loss of shore power provide for a detailed case study. Aquistore, managed by the Petroleum Technology Research Centre, is Canada's first dedicated CO2 storage project, and is an integral component of SaskPower's Boundary Dam Integrated Carbon Capture and Storage (CCS) Demonstration project - the world's first fully integrated CCS demonstration project from a coal-fired power plant.

Principles of designing cyber-physical system of producing mechanical assembly components at Industry 4.0 enterprise

NASA Astrophysics Data System (ADS)

Gurjanov, A. V.; Zakoldaev, D. A.; Shukalov, A. V.; Zharinov, I. O.

2018-03-01

The task of developing principles of cyber-physical system constitution at the Industry 4.0 company of the item designing components of mechanical assembly production is being studied. The task has been solved by analyzing the components and technologies, which have some practical application in the digital production organization. The list of components has been defined and the authors proposed the scheme of the components and technologies interconnection in the Industry 4.0 of mechanical assembly production to make an uninterrupted manufacturing route of the item designing components with application of some cyber-physical systems.

High power and spectral purity continuous-wave photonic THz source tunable from 1 to 4.5 THz for nonlinear molecular spectroscopy

NASA Astrophysics Data System (ADS)

Kiessling, J.; Breunig, I.; Schunemann, P. G.; Buse, K.; Vodopyanov, K. L.

2013-10-01

We report a diffraction-limited photonic terahertz (THz) source with linewidth <10 MHz that can be used for nonlinear THz studies in the continuous wave (CW) regime with uninterrupted tunability in a broad range of THz frequencies. THz output is produced in orientation-patterned (OP) gallium arsenide (GaAs) via intracavity frequency mixing between the two closely spaced resonating signal and idler waves of an optical parametric oscillator (OPO) operating near λ = 2 μm. The doubly resonant type II OPO is based on a periodically poled lithium niobate (PPLN) pumped by a single-frequency Yb:YAG disc laser at 1030 nm. We take advantage of the enhancement of both optical fields inside a high-finesse OPO cavity: with 10 W of 1030 nm pump, 100 W of intracavity power near 2 μm was attained with GaAs inside cavity. This allows dramatic improvement in terms of generated THz power, as compared to the state-of-the art CW methods. We achieved >25 μW of single-frequency tunable CW THz output power scalable to >1 mW with proper choice of pump laser wavelength.

Rapid restoration of electric vehicle battery performance while driving at cold temperatures

NASA Astrophysics Data System (ADS)

Zhang, Guangsheng; Ge, Shanhai; Yang, Xiao-Guang; Leng, Yongjun; Marple, Dan; Wang, Chao-Yang

2017-12-01

Electric vehicles (EVs) driven in cold weather experience two major drawbacks of Li-ion batteries: drastic power loss (up to 10-fold at -30 °C) and restriction of regenerative braking at temperatures below 5-10 °C. Both factors greatly reduce cruise range, exacerbating drivers' range anxiety in winter. While preheating the battery before driving is a practice widely adopted to maintain battery power and EV drivability, it is time-consuming (on the order of 40 min) and prohibits instantaneous mobility. Here we reveal a control strategy that can rapidly restore EV battery power and permit full regeneration while driving at temperatures as low as -40 °C. The strategy involves heating the battery internally during regenerative braking and rest periods of driving. We show that this technique fully restores room-temperature battery power and regeneration in 13, 33, 46, 56 and 112 s into uninterrupted driving in 0, -10, -20, -30 and -40 °C environments, respectively. Correspondingly, the strategy significantly increases cruise range of a vehicle operated at cold temperatures, e.g. 49% at -40 °C in simulated US06 driving cycle tests. The present work suggests that smart batteries with embedded sensing/actuation can leapfrog in performance.

Experimental control of sea lampreys with electricity on the south shore of Lake Superior, 1953-60

USGS Publications Warehouse

McLain, Alberton L.; Smith, Bernard R.; Moore, Harry H.

1965-01-01

Electric devices of the type and design used are capable of blocking entire runs of adult sea lampreys. An accurate appraisal of the effectiveness of the barrier system is impossible, however. Most of the barriers were not operated long enough to reduce the contribution of parasites from the streams. Furthermore, a complete system of efficient electric barriers was never realized. The greatest weakness of this method of control lies in maintenance of the units in continuous, uninterrupted operation through consecutive migratory seasons.

Maintenance-free operation of WDM quantum key distribution system through a field fiber over 30 days

NASA Astrophysics Data System (ADS)

Yoshino, Ken-ichiro; Ochi, Takao; Fujiwara, Mikio; Sasaki, Masahide; Tajima, Akio

2013-12-01

Maintenance-free wavelength-division-multiplexing quantum key distribution for 30 days was achieved through a 22-km field fiber. Using polarization-independent interferometers and stabilization techniques, we attained a quantum bit error rate as low as 1.70% and a key rate as high as 229.8 kbps, making the record of total secure key of 595.6 Gbits accumulated over an uninterrupted operation period.

Development of a self-made framework for the acquisition and communication of real-time precipitation data

NASA Astrophysics Data System (ADS)

Pedrozo-Acuña, A.; Magos-Hernández, J. A.; Sánchez-Peralta, J. A.; Blanco-Figueroa, J.; Breña-Naranjo, J. A.

2017-12-01

This contribution presents a real-time system for issuing warnings of intense precipitation events during major storms, developed for Mexico City, Mexico. The system is based on high-temporal resolution (Dt=1min) measurements of precipitation in 10 different points within the city, which report variables such as intensity, number of raindrops, raindrop size, kinetic energy, fall velocity, etc. Each one of these stations, is comprised of an optical disdrometer to measure size and fall velocity of hydrometeors, a solar panel to guarantee an uninterrupted power supply, a wireless broadband access to internet, and a resource constrained device known as Raspberry Pi3 for the processing, storage and sharing of the sensor data over the world wide web. The self-made developed platform follows a component-based system paradigm allowing users to implement custom algorithms and models depending on application requirements. The system is in place since July 2016, and continuous measurements of rainfall in real-time are published over the internet through the webpage www.oh-iiunam.mx. Additionally, the developed platform for the data collection and management interacts with the social network known as Twitter to enable real-time warnings of precipitation events. Key contribution of this development is the design and implementation of a scalable, easy to use, interoperable platform that facilitates the development of real-time precipitation sensor networks and warnings. The system is easy to implement and could be used as a prototype for systems in other regions of the world.

Lunar oxygen and metal for use in near-earth space - Magma electrolysis

NASA Technical Reports Server (NTRS)

Colson, Russell O.; Haskin, Larry A.

1990-01-01

The unique conditions on the moon, such as vacuum, absence of many reagents common on the earth, and presence of very nontraditional 'ores', suggest that a unique and nontraditional process for extracting materials from the ores may prove the most practical. An investigation has begun into unfluxed silicate electrolysis as a method for extracting oxygen, Fe, and Si from lunar regolith. The advantages of the process include simplicity of concept, absence of need to supply reagents from the earth, and low power and mass requirements for the processing plant. Disadvantages include the need for uninterrupted high temperature and the highly corrosive nature of the high-temperature silicate melts, which has made identifying suitable electrode and container materials difficult.

Continuous-Wave Operation of a Frequency-Tunable 460-GHz Second-Harmonic Gyrotron for Enhanced Nuclear Magnetic Resonance

PubMed Central

Torrezan, Antonio C.; Han, Seong-Tae; Mastovsky, Ivan; Shapiro, Michael A.; Sirigiri, Jagadishwar R.; Temkin, Richard J.; Griffin, Robert G.; Barnes, Alexander B.

2012-01-01

The design, operation, and characterization of a continuous-wave (CW) tunable second-harmonic 460-GHz gyrotron are reported. The gyrotron is intended to be used as a submillimeter-wave source for 700-MHz nuclear magnetic resonance experiments with sensitivity enhanced by dynamic nuclear polarization. The gyrotron operates in the whispering-gallery mode TE11,2 and has generated 16 W of output power with a 13-kV 100-mA electron beam. The start oscillation current measured over a range of magnetic field values is in good agreement with theoretical start currents obtained from linear theory for successive high-order axial modes TE11,2,q. The minimum start current is 27 mA. Power and frequency tuning measurements as a function of the electron cyclotron frequency have also been carried out. A smooth frequency tuning range of 1 GHz was obtained for the operating second-harmonic mode either by magnetic field tuning or beam voltage tuning. Long-term CW operation was evaluated during an uninterrupted period of 48 h, where the gyrotron output power and frequency were kept stable to within ±0.7% and ±6 ppm, respectively, by a computerized control system. Proper operation of an internal quasi-optical mode converter implemented to transform the operating whispering-gallery mode to a Gaussian-like beam was also verified. Based on the images of the gyrotron output beam taken with a pyroelectric camera, the Gaussian-like mode content of the output beam was computed to be 92% with an ellipticity of 12%. PMID:23761938

Continuous-Wave Operation of a Frequency-Tunable 460-GHz Second-Harmonic Gyrotron for Enhanced Nuclear Magnetic Resonance

PubMed Central

Torrezan, Antonio C.; Han, Seong-Tae; Mastovsky, Ivan; Shapiro, Michael A.; Sirigiri, Jagadishwar R.; Temkin, Richard J.; Barnes, Alexander B.; Griffin, Robert G.

2011-01-01

The design, operation, and characterization of a continuous-wave (CW) tunable second-harmonic 460-GHz gyrotron are reported. The gyrotron is intended to be used as a submillimeter-wave source for 700-MHz nuclear magnetic resonance experiments with sensitivity enhanced by dynamic nuclear polarization. The gyrotron operates in the whispering-gallery mode TE11,2 and has generated 16 W of output power with a 13-kV 100-mA electron beam. The start oscillation current measured over a range of magnetic field values is in good agreement with theoretical start currents obtained from linear theory for successive high-order axial modes TE11,2,q. The minimum start current is 27 mA. Power and frequency tuning measurements as a function of the electron cyclotron frequency have also been carried out. A smooth frequency tuning range of 1 GHz was obtained for the operating second-harmonic mode either by magnetic field tuning or beam voltage tuning. Long-term CW operation was evaluated during an uninterrupted period of 48 h, where the gyrotron output power and frequency were kept stable to within ±0.7% and ±6 ppm, respectively, by a computerized control system. Proper operation of an internal quasi-optical mode converter implemented to transform the operating whispering-gallery mode to a Gaussian-like beam was also verified. Based on the images of the gyrotron output beam taken with a pyroelectric camera, the Gaussian-like mode content of the output beam was computed to be 92% with an ellipticity of 12%. PMID:21243088

A cryogen-free low temperature scanning tunneling microscope capable of inelastic electron tunneling spectroscopy.

PubMed

Zhang, Shuai; Huang, Di; Wu, Shiwei

2016-06-01

The design and performance of a cryogen-free low temperature scanning tunneling microscope (STM) housed in ultrahigh vacuum (UHV) are reported. The cryogen-free design was done by directly integrating a Gifford-McMahon cycle cryocooler to a Besocke-type STM, and the vibration isolation was achieved by using a two-stage rubber bellow between the cryocooler and a UHV-STM interface with helium exchange gas cooling. A base temperature of 15 K at the STM was achieved, with a possibility to further decrease by using a cryocooler with higher cooling power and adding additional low temperature stage under the exchange gas interface. Atomically sharp STM images and high resolution dI/dV spectra on various samples were demonstrated. Furthermore, we reported the inelastic tunneling spectroscopy on a single carbon monoxide molecule adsorbed on Ag(110) surface with a cryogen-free STM for the first time. Being totally cryogen-free, the system not only saves the running cost significantly but also enables uninterrupted data acquisitions and variable temperature measurements with much ease. In addition, the system is capable of coupling light to the STM junction by a pair of lens inside the UHV chamber. We expect that these enhanced capabilities could further broaden our views to the atomic-scale world.

A cryogen-free low temperature scanning tunneling microscope capable of inelastic electron tunneling spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Shuai; Huang, Di; Wu, Shiwei, E-mail: swwu@fudan.edu.cn

The design and performance of a cryogen-free low temperature scanning tunneling microscope (STM) housed in ultrahigh vacuum (UHV) are reported. The cryogen-free design was done by directly integrating a Gifford-McMahon cycle cryocooler to a Besocke-type STM, and the vibration isolation was achieved by using a two-stage rubber bellow between the cryocooler and a UHV-STM interface with helium exchange gas cooling. A base temperature of 15 K at the STM was achieved, with a possibility to further decrease by using a cryocooler with higher cooling power and adding additional low temperature stage under the exchange gas interface. Atomically sharp STM imagesmore » and high resolution dI/dV spectra on various samples were demonstrated. Furthermore, we reported the inelastic tunneling spectroscopy on a single carbon monoxide molecule adsorbed on Ag(110) surface with a cryogen-free STM for the first time. Being totally cryogen-free, the system not only saves the running cost significantly but also enables uninterrupted data acquisitions and variable temperature measurements with much ease. In addition, the system is capable of coupling light to the STM junction by a pair of lens inside the UHV chamber. We expect that these enhanced capabilities could further broaden our views to the atomic-scale world.« less

Environmental Assessment: Demolish CASS Switch Stations Buildings 644, 645, 646 at Grand Forks Air Force Base

DTIC Science & Technology

2006-06-01

Per Year TSCA Toxic Substance Control Act TSI Thermal System Insulation UAV Unmanned Aerial Vehicle UHF Ultra High Frequency UPS Uninterruptible...Conservation and Recovery Act (RCRA) of 1976 [42 U.S.C. Sec. 6901, et seq.] • Toxic Substances Control Act (TSCA) of 1976 [15 U.S.C. Sec. 2601, et...Corporation (SAIC). Typical hazardous materials include reactive materials such as explosives, ignitables, toxics , and corrosives. Improper storage can

Multi-loop control of UPS inverter with a plug-in odd-harmonic repetitive controller.

PubMed

Razi, Reza; Karbasforooshan, Mohammad-Sadegh; Monfared, Mohammad

2017-03-01

This paper proposes an improved multi-loop control scheme for the single-phase uninterruptible power supply (UPS) inverter by using a plug-in odd-harmonic repetitive controller to regulate the output voltage. In the suggested control method, the output voltage and the filter capacitor current are used as the outer and inner loop feedback signals, respectively and the instantaneous value of the reference voltage feedforwarded to the output of the controller. Instead of conventional linear (proportional-integral/-resonant) and conventional repetitive controllers, a plug-in odd-harmonic repetitive controller is employed in the outer loop to regulate the output voltage, which occupies less memory space and offers faster tracking performance compared to the conventional one. Also, a simple proportional controller is used in the inner loop for active damping of possible resonances and improving the transient performance. The feedforward of the converter reference voltage enhances the robust performance of the system and simplifies the system modelling and the controller design. A step-by-step design procedure is presented for the proposed controller, which guarantees stability of the system under worst-case scenarios. Simulation and experimental results validate the excellent steady-state and transient performance of the proposed control scheme and provide the exact comparison of the proposed method with the conventional multi-loop control method. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

ACT-Vision: active collaborative tracking for multiple PTZ cameras

NASA Astrophysics Data System (ADS)

Broaddus, Christopher; Germano, Thomas; Vandervalk, Nicholas; Divakaran, Ajay; Wu, Shunguang; Sawhney, Harpreet

2009-04-01

We describe a novel scalable approach for the management of a large number of Pan-Tilt-Zoom (PTZ) cameras deployed outdoors for persistent tracking of humans and vehicles, without resorting to the large fields of view of associated static cameras. Our system, Active Collaborative Tracking - Vision (ACT-Vision), is essentially a real-time operating system that can control hundreds of PTZ cameras to ensure uninterrupted tracking of target objects while maintaining image quality and coverage of all targets using a minimal number of sensors. The system ensures the visibility of targets between PTZ cameras by using criteria such as distance from sensor and occlusion.

Tracking and characterizing the head motion of unanaesthetized rats in positron emission tomography

PubMed Central

Kyme, Andre; Meikle, Steven; Baldock, Clive; Fulton, Roger

2012-01-01

Positron emission tomography (PET) is an important in vivo molecular imaging technique for translational research. Imaging unanaesthetized rats using motion-compensated PET avoids the confounding impact of anaesthetic drugs and enables animals to be imaged during normal or evoked behaviour. However, there is little published data on the nature of rat head motion to inform the design of suitable marker-based motion-tracking set-ups for brain imaging—specifically, set-ups that afford close to uninterrupted tracking. We performed a systematic study of rat head motion parameters for unanaesthetized tube-bound and freely moving rats with a view to designing suitable motion-tracking set-ups in each case. For tube-bound rats, using a single appropriately placed binocular tracker, uninterrupted tracking was possible greater than 95 per cent of the time. For freely moving rats, simulations and measurements of a live subject indicated that two opposed binocular trackers are sufficient (less than 10% interruption to tracking) for a wide variety of behaviour types. We conclude that reliable tracking of head pose can be achieved with marker-based optical-motion-tracking systems for both tube-bound and freely moving rats undergoing PET studies without sedation. PMID:22718992

Stochastic Drought Risk Analysis and Projection Methods For Thermoelectric Power Systems

NASA Astrophysics Data System (ADS)

Bekera, Behailu Belamo

Combined effects of socio-economic, environmental, technological and political factors impact fresh cooling water availability, which is among the most important elements of thermoelectric power plant site selection and evaluation criteria. With increased variability and changes in hydrologic statistical stationarity, one concern is the increased occurrence of extreme drought events that may be attributable to climatic changes. As hydrological systems are altered, operators of thermoelectric power plants need to ensure a reliable supply of water for cooling and generation requirements. The effects of climate change are expected to influence hydrological systems at multiple scales, possibly leading to reduced efficiency of thermoelectric power plants. This study models and analyzes drought characteristics from a thermoelectric systems operational and regulation perspective. A systematic approach to characterize a stream environment in relation to extreme drought occurrence, duration and deficit-volume is proposed and demonstrated. More specifically, the objective of this research is to propose a stochastic water supply risk analysis and projection methods from thermoelectric power systems operation and management perspectives. The study defines thermoelectric drought as a shortage of cooling water due to stressed supply or beyond operable water temperature limits for an extended period of time requiring power plants to reduce production or completely shut down. It presents a thermoelectric drought risk characterization framework that considers heat content and water quantity facets of adequate water availability for uninterrupted operation of such plants and safety of its surroundings. In addition, it outlines mechanisms to identify rate of occurrences of the said droughts and stochastically quantify subsequent potential losses to the sector. This mechanism is enabled through a model based on compound Nonhomogeneous Poisson Process. This study also demonstrates how the systematic approach can be used for better understanding of pertinent vulnerabilities by providing risk-based information to stakeholders in the power sector. Vulnerabilities as well as our understanding of their extent and likelihood change over time. Keeping up with the changes and making informed decisions demands a time-dependent method that incorporates new evidence into risk assessment framework. This study presents a statistical time-dependent risk analysis approach, which allows for life cycle drought risk assessment of thermoelectric power systems. Also, a Bayesian Belief Network (BBN) extension to the proposed framework is developed. The BBN allows for incorporating new evidence, such as observing power curtailments due to extreme heat or lowflow situations, and updating our knowledge and understanding of the pertinent risk. In sum, the proposed approach can help improve adaptive capacity of the electric power infrastructure, thereby enhancing its resilience to events potentially threatening grid reliability and economic stability. The proposed drought characterization methodology is applied on a daily streamflow series obtained from three United States Geological Survey (USGS) water gauges on the Tennessee River basin. The stochastic water supply risk assessment and projection methods are demonstrated for two power plants on the White River, Indiana: Frank E. Ratts and Petersburg, using water temperature and streamflow time series data obtained from a nearby USGS gauge.

An evaluation of interrupted and uninterrupted measurement of vocal stereotypy on perceived treatment outcomes.

PubMed

Carroll, Regina A; Kodak, Tiffany

2014-01-01

The type of procedure used to measure a target behavior may directly influence the perceived treatment outcomes. In the present study, we examined the influence of different data-analysis procedures on the outcomes of two commonly used treatments on the vocal stereotypy of 2 children with an autism spectrum disorder. In Study 1, we compared an interrupted and uninterrupted data-analysis procedure to measure vocal stereotypy during the implementation of response interruption and redirection (RIRD). The results showed that the interrupted data-analysis procedure overestimated the effectiveness of RIRD. In Study 2, we examined the influence of different data-analysis procedures on the interpretation of the relative effects of 2 different treatments for vocal stereotypy. Specifically, we compared interrupted and uninterrupted data-analysis procedures during the implementation of RIRD and noncontingent reinforcement (NCR) as a treatment for vocal stereotypy. The results showed that, as in Study 1, the interrupted data-analysis procedure overestimated the effectiveness of RIRD; however, this effect was not apparent with NCR. These findings suggest that different types of data analysis can influence the perceived success of a treatment. © Society for the Experimental Analysis of Behavior.

Controlled overspray spray nozzle

NASA Technical Reports Server (NTRS)

Prasthofer, W. P. (Inventor)

1981-01-01

A spray system for a multi-ingredient ablative material wherein a nozzle A is utilized for suppressing overspray is described. The nozzle includes a cyclindrical inlet which converges to a restricted throat. A curved juncture between the cylindrical inlet and the convergent portion affords unrestricted and uninterrupted flow of the ablative material. A divergent bell-shaped chamber and adjustable nozzle exit B is utilized which provides a highly effective spray pattern in suppressing overspray to an acceptable level and producing a homogeneous jet of material that adheres well to the substrate.

Evolution of the Building Management System in the INFN CNAF Tier-1 data center facility.

NASA Astrophysics Data System (ADS)

Ricci, Pier Paolo; Donatelli, Massimo; Falabella, Antonio; Mazza, Andrea; Onofri, Michele

2017-10-01

The INFN CNAF Tier-1 data center is composed by two different main rooms containing IT resources and four additional locations that hosts the necessary technology infrastructures providing the electrical power and cooling to the facility. The power supply and continuity are ensured by a dedicated room with three 15,000 to 400 V transformers in a separate part of the principal building and two redundant 1.4MW diesel rotary uninterruptible power supplies. The cooling is provided by six free cooling chillers of 320 kW each with a N+2 redundancy configuration. Clearly, considering the complex physical distribution of the technical plants, a detailed Building Management System (BMS) was designed and implemented as part of the original project in order to monitor and collect all the necessary information and for providing alarms in case of malfunctions or major failures. After almost 10 years of service, a revision of the BMS system was somewhat necessary. In addition, the increasing cost of electrical power is nowadays a strong motivation for improving the energy efficiency of the infrastructure. Therefore the exact calculation of the power usage effectiveness (PUE) metric has become one of the most important factors when aiming for the optimization of a modern data center. For these reasons, an evolution of the BMS system was designed using the Schneider StruxureWare infrastructure hardware and software products. This solution proves to be a natural and flexible development of the previous TAC Vista software with advantages in the ease of use and the possibility to customize the data collection and the graphical interfaces display. Moreover, the addition of protocols like open standard Web services gives the possibility to communicate with the BMS from custom user application and permits the exchange of data and information through the Web between different third-party systems. Specific Web services SOAP requests has been implemented in our Tier-1 monitoring system in order to collect historical trends of power demands and calculate the partial PUE (pPUE) of a specific part of the infrastructure. This would help in the identification of “spots” that may need further energy optimization. The StruxureWare system maintains compatibility with standard protocols like Modbus as well as native LonWorks, making possible reusing the existing network between physical locations as well as a considerable number of programmable controller and I/O modules that interact with the facility. The high increase of detailed statistical information about power consumption and the HVAC (heat, ventilation and air conditioning) parameters could prove to be a very valuable strategic choice for improving the overall PUE. This will bring remarkable benefits for the overall management costs, despite the limits of the non-optimal actual location of the facility, and it will help us in the process of making a more energy efficient data center that embraces the concept of green IT.

The control, monitor, and alarm system for the ICT equipment of the ASTRI SST-2M telescope prototype for the Cherenkov Telescope Array

NASA Astrophysics Data System (ADS)

Gianotti, Fulvio; Fioretti, Valentina; Tanci, Claudio; Conforti, Vito; Tacchini, Alessandro; Leto, Giuseppe; Gallozzi, Stefano; Bulgarelli, Andrea; Trifoglio, Massimo; Malaguti, Giuseppe; Zoli, Andrea

2014-07-01

ASTRI is an Italian flagship project whose first goal is the realization of an end-to-end telescope prototype, named ASTRI SST-2M, for the Cherenkov Telescope Array (CTA). The prototype will be installed in Italy during Fall 2014. A second goal will be the realization of the ASTRI/CTA mini-array which will be composed of seven SST-2M telescopes placed at the CTA Southern Site. The Information and Communication Technology (ICT) equipment necessary to drive the infrastructure for the ASTRI SST-2M prototype is being designed as a complete and stand-alone computer center. The design goal is to obtain basic ICT equipment that might be scaled, with a low level of redundancy, for the ASTRI/CTA mini-array, taking into account the necessary control, monitor and alarm system requirements. The ICT equipment envisaged at the Serra La Nave observing station in Italy, where the ASTRI SST-2M telescope prototype will operate, includes computers, servers and workstations, network devices, an uninterruptable power supply system, and air conditioning systems. Suitable hardware and software tools will allow the parameters related to the behavior and health of each item of equipment to be controlled and monitored. This paper presents the proposed architecture and technical solutions that integrate the ICT equipment in the framework of the Observatory Control System package of the ASTRI/CTA Mini- Array Software System, MASS, to allow their local and remote control and monitoring. An end-toend test case using an Internet Protocol thermometer is reported in detail.

Intelligent voltage control strategy for three-phase UPS inverters with output LC filter

NASA Astrophysics Data System (ADS)

Jung, J. W.; Leu, V. Q.; Dang, D. Q.; Do, T. D.; Mwasilu, F.; Choi, H. H.

2015-08-01

This paper presents a supervisory fuzzy neural network control (SFNNC) method for a three-phase inverter of uninterruptible power supplies (UPSs). The proposed voltage controller is comprised of a fuzzy neural network control (FNNC) term and a supervisory control term. The FNNC term is deliberately employed to estimate the uncertain terms, and the supervisory control term is designed based on the sliding mode technique to stabilise the system dynamic errors. To improve the learning capability, the FNNC term incorporates an online parameter training methodology, using the gradient descent method and Lyapunov stability theory. Besides, a linear load current observer that estimates the load currents is used to exclude the load current sensors. The proposed SFNN controller and the observer are robust to the filter inductance variations, and their stability analyses are described in detail. The experimental results obtained on a prototype UPS test bed with a TMS320F28335 DSP are presented to validate the feasibility of the proposed scheme. Verification results demonstrate that the proposed control strategy can achieve smaller steady-state error and lower total harmonic distortion when subjected to nonlinear or unbalanced loads compared to the conventional sliding mode control method.

Flywheel Rotor Safe-Life Technology

NASA Technical Reports Server (NTRS)

Ratner, J. K. H.; Chang, J. B.; Christopher, D. A.; McLallin, Kerry L. (Technical Monitor)

2002-01-01

Since the 1960s, research has been conducted into the use of flywheels as energy storage systems. The-proposed applications include energy storage for hybrid and electric automobiles, attitude control and energy storage for satellites, and uninterruptible power supplies for hospitals and computer centers. For many years, however, the use of flywheels for space applications was restricted by the total weight of a system employing a metal rotor. With recent technological advances in the manufacturing of composite materials, however, lightweight composite rotors have begun to be proposed for such applications. Flywheels with composite rotors provide much higher power and energy storage capabilities than conventional chemical batteries. However, the failure of a high speed flywheel rotor could be a catastrophic event. For this reason, flywheel rotors are classified by the NASA Fracture Control Requirements Standard as fracture critical parts. Currently, there is no industry standard to certify a composite rotor for safe and reliable operation forth( required lifetime of the flywheel. Technical problems hindering the development of this standard include composite manufacturing inconsistencies, insufficient nondestructive evaluation (NDE) techniques for detecting defects and/or impact damage, lack of standard material test methods for characterizing composite rotor design allowables, and no unified proof (over-spin) test for flight rotors. As part of a flywheel rotor safe-life certification pro-ram funded b the government, a review of the state of the art in composite rotors is in progress. The goal of the review is to provide a clear picture of composite flywheel rotor technologies. The literature review has concentrated on the following topics concerning composites and composite rotors: durability (fatigue) and damage tolerance (safe-life) analysis/test methods, in-service NDE and health monitoring techniques, spin test methods/ procedures, and containment options. This report presents the papers selected for their relevance to this topic and summarizes them.

Task 2: Flight prototype system design report, pulsed plasma solid propellant microthruster for the Synchronous Meteorological Satellite

NASA Technical Reports Server (NTRS)

Guman, W. J. (Editor)

1972-01-01

Design details are presented of the solid propellant pulsed plasma microthruster which was analyzed during the Task 1 effort. The design details presented show that the inherent functional simplicity underlying the flight proven LES-6 design can be maintained in the SMS systems design even with minimum weight constraints imposed. A 1293 hour uninterrupted vacuum test with the engineering thermal model, simulating an 18.8 to 33 g environment of the propellant, its feed system and electrode assembly, revealed that program thruster performance requirements could be met. This latter g environment is a more severe environment than will be ever encountered in the SMS spacecraft.

Mounting for ceramic scroll

DOEpatents

Petty, Jack D.

1993-01-01

A mounting for a ceramic scroll on a metal engine block of a gas turbine engine includes a first ceramic ring and a pair of cross key connections between the first ceramic ring, the ceramic scroll, and the engine block. The cross key connections support the scroll on the engine block independent of relative radial thermal growth and for bodily movement toward an annular mounting shoulder on the engine. The scroll has an uninterrupted annular shoulder facing the mounting shoulder on the engine block. A second ceramic ring is captured between mounting shoulder and the uninterrupted shoulder on the scroll when the latter is bodily shifted toward the mouting shoulder to define a gas seal between the scroll and the engine block.

21 CFR 1315.30 - Procurement and import quotas.

Code of Federal Regulations, 2014 CFR

2014-04-01

... PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas... adequate and uninterrupted supply of, ephedrine, pseudoephedrine, and phenylpropanolamine the Administrator...

21 CFR 1315.30 - Procurement and import quotas.

Code of Federal Regulations, 2011 CFR

2011-04-01

... PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas... adequate and uninterrupted supply of, ephedrine, pseudoephedrine, and phenylpropanolamine the Administrator...

21 CFR 1315.30 - Procurement and import quotas.

Code of Federal Regulations, 2010 CFR

2010-04-01

... PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas... adequate and uninterrupted supply of, ephedrine, pseudoephedrine, and phenylpropanolamine the Administrator...

21 CFR 1315.30 - Procurement and import quotas.

Code of Federal Regulations, 2012 CFR

2012-04-01

... PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas... adequate and uninterrupted supply of, ephedrine, pseudoephedrine, and phenylpropanolamine the Administrator...

21 CFR 1315.30 - Procurement and import quotas.

Code of Federal Regulations, 2013 CFR

2013-04-01

... PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas... adequate and uninterrupted supply of, ephedrine, pseudoephedrine, and phenylpropanolamine the Administrator...

Nocturnal Polyuria in Older Women with Urge Urinary Incontinence: Role of Sleep Quality, Time in Bed and Medications Used.

PubMed

Tyagi, Shachi; Perera, Subashan; Clarkson, Becky D; Tadic, Stasa D; Resnick, Neil M

2017-03-01

Nocturia is common and bothersome in older adults, especially those who are also incontinent. Since nocturnal polyuria is a major contributor, we examined factors associated with nocturnal polyuria in this population to identify those possibly amenable to intervention. We analyzed baseline data from 2 previously completed studies of urge urinary incontinence. The studies involved 284 women (mean age ± SD 72.9 ± 7.9 years) who also completed 3-day voiding diaries. Participants with a nocturnal polyuria index greater than 33% were categorized as having nocturnal polyuria (nocturnal polyuria index = nocturnal urinary volume per 24-hour urine volume). Associations between nocturnal polyuria and various demographic, clinical and sleep related parameters were determined. Overall 55% of the participants had nocturnal polyuria. Multivariable regression analysis revealed that age, body mass index, use of angiotensin converting enzyme inhibitor/angiotensin receptor blocker, time spent in bed and duration of first uninterrupted sleep were independent correlates of nocturnal polyuria. Participants with a larger nocturnal excretion reported a shorter duration of uninterrupted sleep before first awakening to void and worse sleep quality despite spending similar time in bed. Body mass index, use of angiotensin converting enzyme inhibitor/angiotensin receptor blockers, time in bed and duration of uninterrupted sleep before first awakening to void are independently associated with nocturnal polyuria in older women with urge urinary incontinence, and are potentially modifiable. These findings also confirm the association between sleep and nocturnal polyuria. Further studies should explore whether interventions to reduce nocturnal polyuria and/or increase the duration of uninterrupted sleep before first awakening to void would help to improve sleep quality in this population and thereby reduce or eliminate the need for sedative hypnotics. Copyright © 2017 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Project Plan 7930 Cell G PaR Remote Handling System Replacement

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kinney, Kathryn A

2009-10-01

For over 40 years the US Department of Energy (DOE) and its predecessors have made Californium-252 ({sup 252}Cf) available for a wide range of industries including medical, nuclear fuels, mining, military and national security. The Radiochemical Engineering Development Center (REDC) located within the Oak Ridge National Laboratory (ORNL) processes irradiated production targets from the High Flux Isotope Reactor (HFIR). Operations in Building 7930, Cell G provide over 70% of the world's demand for {sup 252}Cf. Building 7930 was constructed and equipped in the mid-1960s. Current operations for {sup 252}Cf processing in Building 7930, Cell G require use of through-the-wall manipulatorsmore » and the PaR Remote Handling System. Maintenance and repairs for the manipulators is readily accomplished by removal of the manipulator and relocation to a repair shop where hands-on work can be performed in glove boxes. Contamination inside cell G does not currently allow manned entry and no provisions were created for a maintenance area inside the cell. There has been no maintenance of the PaR system or upgrades, leaving operations vulnerable should the system have a catastrophic failure. The Cell G PaR system is currently being operated in a run to failure mode. As the manipulator is now 40+ years old there is significant risk in this method of operation. In 2006 an assessment was completed that resulted in recommendations for replacing the manipulator operator control and power centers which are used to control and power the PaR manipulator in Cell G. In mid-2008 the chain for the bridge drive failed and subsequent examinations indicated several damaged links (see Figure 1). To continue operations the PaR manipulator arm is being used to push and pull the bridge as a workaround. A retrieval tool was fabricated, tested and staged inside Cell G that will allow positioning of the bridge and manipulator arm for removal from the cell should the PaR system completely fail. A fully functioning and reliable Par manipulator arm is necessary for uninterrupted {sup 252}Cf operations; a fully-functioning bridge is needed for the system to function as intended.« less

Round-the-clock power supply and a sustainable economy via synergistic integration of solar thermal power and hydrogen processes

PubMed Central

Gençer, Emre; Mallapragada, Dharik S.; Maréchal, François; Tawarmalani, Mohit; Agrawal, Rakesh

2015-01-01

We introduce a paradigm—“hydricity”—that involves the coproduction of hydrogen and electricity from solar thermal energy and their judicious use to enable a sustainable economy. We identify and implement synergistic integrations while improving each of the two individual processes. When the proposed integrated process is operated in a standalone, solely power production mode, the resulting solar water power cycle can generate electricity with unprecedented efficiencies of 40–46%. Similarly, in standalone hydrogen mode, pressurized hydrogen is produced at efficiencies approaching ∼50%. In the coproduction mode, the coproduced hydrogen is stored for uninterrupted solar power production. When sunlight is unavailable, we envision that the stored hydrogen is used in a “turbine”-based hydrogen water power (H2WP) cycle with the calculated hydrogen-to-electricity efficiency of 65–70%, which is comparable to the fuel cell efficiencies. The H2WP cycle uses much of the same equipment as the solar water power cycle, reducing capital outlays. The overall sun-to-electricity efficiency of the hydricity process, averaged over a 24-h cycle, is shown to approach ∼35%, which is nearly the efficiency attained by using the best multijunction photovoltaic cells along with batteries. In comparison, our proposed process has the following advantages: (i) It stores energy thermochemically with a two- to threefold higher density, (ii) coproduced hydrogen has alternate uses in transportation/chemical/petrochemical industries, and (iii) unlike batteries, the stored energy does not discharge over time and the storage medium does not degrade with repeated uses. PMID:26668380

Wide Bandgap Semiconductor Opportunities in Power Electronics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Das, Sujit; Marlino, Laura D.; Armstrong, Kristina O.

The report objective is to explore the Wide Bandgap (WBG) Power Electronics (PE) market, applications, and potential energy savings in order to identify key areas where further resources and investments of the U.S. Department of Energy’s Office of Energy Efficiency and Renewable Energy (DOE EERE) would have the most impact on U.S. competiveness. After considering the current market, several potential near-term application areas were identified as having significant market and energy savings potential with respect to clean energy applications: (1) data centers (uninterruptible power supplies and server power supplies); (2) renewable energy generation (photovoltaic-solar and wind); (3) motor drives (industrial,more » commercial and residential); (4) rail traction; and, (5) hybrid and electric vehicles (traction and charging). After the initial explorative analyses, it became clear that, SiC, not GaN, would be the principal WBG power device material for the chosen markets in the near future. Therefore, while GaN is discussed when appropriate, this report focuses on SiC devices, other WBG applications (e.g., solid-state transformers, combined heat and power, medical, and wireless power), the GaN market, and GaN specific applications (e.g., LiDAR, 5G) will be explored at a later date. In addition to the market, supply and value chain analyses addressed in Section 1 of this report, a SWOT (Strength, Weakness, Opportunity, Threat) analysis and potential energy savings analysis was conducted for each application area to identify the major potential WBG application area(s) with a U.S. competitiveness opportunity in the future.« less

Round-the-clock power supply and a sustainable economy via synergistic integration of solar thermal power and hydrogen processes.

PubMed

Gençer, Emre; Mallapragada, Dharik S; Maréchal, François; Tawarmalani, Mohit; Agrawal, Rakesh

2015-12-29

We introduce a paradigm-"hydricity"-that involves the coproduction of hydrogen and electricity from solar thermal energy and their judicious use to enable a sustainable economy. We identify and implement synergistic integrations while improving each of the two individual processes. When the proposed integrated process is operated in a standalone, solely power production mode, the resulting solar water power cycle can generate electricity with unprecedented efficiencies of 40-46%. Similarly, in standalone hydrogen mode, pressurized hydrogen is produced at efficiencies approaching ∼50%. In the coproduction mode, the coproduced hydrogen is stored for uninterrupted solar power production. When sunlight is unavailable, we envision that the stored hydrogen is used in a "turbine"-based hydrogen water power (H2WP) cycle with the calculated hydrogen-to-electricity efficiency of 65-70%, which is comparable to the fuel cell efficiencies. The H2WP cycle uses much of the same equipment as the solar water power cycle, reducing capital outlays. The overall sun-to-electricity efficiency of the hydricity process, averaged over a 24-h cycle, is shown to approach ∼35%, which is nearly the efficiency attained by using the best multijunction photovoltaic cells along with batteries. In comparison, our proposed process has the following advantages: (i) It stores energy thermochemically with a two- to threefold higher density, (ii) coproduced hydrogen has alternate uses in transportation/chemical/petrochemical industries, and (iii) unlike batteries, the stored energy does not discharge over time and the storage medium does not degrade with repeated uses.

High ratio recirculating gas compressor

DOEpatents

Weinbrecht, J.F.

1989-08-22

A high ratio positive displacement recirculating rotary compressor is disclosed. The compressor includes an integral heat exchanger and recirculation conduits for returning cooled, high pressure discharge gas to the compressor housing to reducing heating of the compressor and enable higher pressure ratios to be sustained. The compressor features a recirculation system which results in continuous and uninterrupted flow of recirculation gas to the compressor with no direct leakage to either the discharge port or the intake port of the compressor, resulting in a capability of higher sustained pressure ratios without overheating of the compressor. 10 figs.

Tibetan medicine. Part I: Introduction to Tibetan medicine and the rGyud-bzi (Fourth Tantra).

PubMed

Prasaad Steiner, R

1987-01-01

Tibetan medicine is one example of a traditional cultural health care system. Until recently, geographic barriers have permitted this medical tradition to evolve in an uninterrupted way. The history, concepts, and foundations of Tibetan medicine are closely interwoven with those of Buddhism in Tibet The following essay is an introductory overview of Tibetan medicine. The purpose of this essay is to provide a conceptual framework and a proper perspective for understanding a highly edited translation of one chapter from a traditional Tibetan medical text.

Gamma-ray monitoring of AGN and galactic black hole candidates by the Gamma-Ray Observatory

NASA Technical Reports Server (NTRS)

Wheaton, Wm. A.; Ling, James C.; Skelton, R. T.; Harmon, Alan; Fishman, Gerald J.; Meegan, Charles A.; Paciesas, William S.; Rubin, Brad; Wilson, Robert B.; Gruber, Duane E.

1992-01-01

The Burst and Transient Spectroscopy Experiment (BATSE) on the Compton Gamma-Ray Observatory has a powerful capability to provide nearly uninterrupted monitoring in the 25 keV-10 MeV range of both AGN and Galactic black hole candidates such as Cygnus X-1, using the occultation of cosmic sources by the Earth. Progress in background modeling indicates that the data accept region, or fit window tau, around the occultation step can be substantially increased over that conservatively assumed in earlier estimates of BATSE's Earth occultation sensitivity. We show samples of large-tau fits to background and source edges. As a result we expect to be able to perform long-term monitoring of Cygnus X-1 and many of the brighter AGN for the duration of the CGRO mission.

Continuity of care: some experiences and thoughts.

PubMed

Volpe, F J

1994-09-01

Continuity of health care is a goal to be achieved. Most are for it. Many claim to provide it. But how do we know we have it? What are the key features of continuity? While dictionaries do not define the phrase "continuity of health care," we do find definitions of "continuity." The Oxford English Dictionary, Second Edition, includes in its definitions: "the state or quality of being uninterrupted in sequence or succession, or in essence or idea; connectedness, coherence, unbroken..." Stedman's Medical Dictionary includes: "absence of interruption, a succession of parts intimately united..." These definitions stress an uninterrupted succession and include the concept that there needs to be a connection to the parts. Without that connection, continuity, in health care delivery or elsewhere, does not exist.

Sun-Burned: Space Weather's Impact on United States National Security

NASA Astrophysics Data System (ADS)

Stebbins, B.

2014-12-01

The heightened media attention surrounding the 2013-14 solar maximum presented an excellent opportunity to examine the ever-increasing vulnerability of US national security and its Department of Defense to space weather. This vulnerability exists for three principal reasons: 1) a massive US space-based infrastructure; 2) an almost exclusive reliance on an aging and stressed continental US power grid; and 3) a direct dependence upon a US economy adapted to the conveniences of space and uninterrupted power. I tailored my research and work for the national security policy maker and military strategists in an endeavor to initiate and inform a substantive dialogue on America's preparation for, and response to, a major solar event that would severely degrade core national security capabilities, such as military operations. Significant risk to the Department of Defense exists from powerful events that could impact its space-based infrastructure and even the terrestrial power grid. Given this ever-present and increasing risk to the United States, my work advocates raising the issue of space weather and its impacts to the level of a national security threat. With the current solar cycle having already peaked and the next projected solar maximum just a decade away, the government has a relatively small window to make policy decisions that prepare the nation and its Defense Department to mitigate impacts from these potentially catastrophic phenomena.

NASA Tech Briefs, June 2011

NASA Technical Reports Server (NTRS)

2011-01-01

Topics covered include: Wind and Temperature Spectrometry of the Upper Atmosphere in Low-Earth Orbit; Health Monitor for Multitasking, Safety-Critical, Real-Time Software; Stereo Imaging Miniature Endoscope; Early Oscillation Detection Technique for Hybrid DC/DC Converters; Parallel Wavefront Analysis for a 4D Interferometer; Schottky Heterodyne Receivers With Full Waveguide Bandwidth; Carbon Nanofiber-Based, High-Frequency, High-Q, Miniaturized Mechanical Resonators; Ultracapacitor-Based Uninterrupted Power Supply System; Coaxial Cables for Martian Extreme Temperature Environments; Using Spare Logic Resources To Create Dynamic Test Points; Autonomous Coordination of Science Observations Using Multiple Spacecraft; Autonomous Phase Retrieval Calibration; EOS MLS Level 1B Data Processing Software, Version 3; Cassini Tour Atlas Automated Generation; Software Development Standard Processes (SDSP); Graphite Composite Panel Polishing Fixture; Material Gradients in Oxygen System Components Improve Safety; Ridge Waveguide Structures in Magnesium-Doped Lithium Niobate; Modifying Matrix Materials to Increase Wetting and Adhesion; Lightweight Magnetic Cooler With a Reversible Circulator; The Invasive Species Forecasting System; Method for Cleanly and Precisely Breaking Off a Rock Core Using a Radial Compressive Force; Praying Mantis Bending Core Breakoff and Retention Mechanism; Scoring Dawg Core Breakoff and Retention Mechanism; Rolling-Tooth Core Breakoff and Retention Mechanism; Vibration Isolation and Stabilization System for Spacecraft Exercise Treadmill Devices; Microgravity-Enhanced Stem Cell Selection; Diagnosis and Treatment of Neurological Disorders by Millimeter-Wave Stimulation; Passive Vaporizing Heat Sink; Remote Sensing and Quantization of Analog Sensors; Phase Retrieval for Radio Telescope and Antenna Control; Helium-Cooled Black Shroud for Subscale Cryogenic Testing; Receive Mode Analysis and Design of Microstrip Reflectarrays; and Chance-Constrained Guidance With Non-Convex Constraints.

Uninterrupted Elections Act

THOMAS, 113th Congress

Rep. Griffith, H. Morgan [R-VA-9

2013-02-15

House - 04/08/2013 Referred to the Subcommittee on Courts, Intellectual Property, And The Internet. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

14 CFR 117.25 - Rest period.

Code of Federal Regulations, 2014 CFR

2014-01-01

... flightcrew member with a minimum of 8 uninterrupted hours of sleep opportunity. (f) If a flightcrew member... of sleep opportunity, the flightcrew member must notify the certificate holder. The flightcrew member...

Freak Waves In The Ocean A~é­ We Need Continuous Measurements!

NASA Astrophysics Data System (ADS)

Liu, P.; Teng, C.; Mori, N.

Freak waves, sometimes also known as rogue waves, are a particular kind of ocean waves that displays a singular, unexpected, and unusually high wave profile with an extraordinarily large and steep trough or crest. The existence of freak waves has be- come widely accepted while it always poses severe hazard to the navy fleets, merchant marines, offshore structures, and virtually all oceanic ventures. Multitudes of seagoing vessels and mariners have encountered freak waves over the years, many had resulted in disasters. The emerging interest in freak waves and the quest to grasp an understand- ing of the phenomenon have inspired numerous theoretical conjectures in recent years. But the practical void of actual field observation on freak waves renders even the well- developed theories remain unverified. Furthermore, the present wave measurement systems, which have been in practice for the last 5 decades, are not at all designed to capture freak waves. We wish therefore to propose and petition to all oceanic scientist and engineers to consider undertaking an unprecedented but technologically feasible practice of making continuous and uninterrupted wave measurements. As freak waves can happen anywhere in the ocean and at anytime, the continuous and uninterrupted measurements at a fixed station would certainly be warranted to document the occur- rence of freak waves, if present, and thus lead to basic realizations of the underlying driving mechanisms.

Gamma ray monitoring of a AGN and galactic black hole candidates by the Compton Gamma Ray Observatory

NASA Technical Reports Server (NTRS)

Skelton, R. T.; Ling, James C.; Wheaton, William A.; Harmon, Alan; Fishman, G. J.; Meegan, C. A.; Paciesas, William S.; Gruber, Duane E.; Rubin, Brad; Wilson, R. B.

1992-01-01

The Compton Gamma-Ray Observatory's Burst and Transient Source Experiment (BATSE) has a powerful capability to provide nearly uninterrupted monitoring in the 25 keV-10 MeV range of both active galactic nuclei (AGN) and galactic black hole candidates (GBHC) such as Cygnus X-1, using the occultation of cosmic sources by the Earth. Since the Crab is detected by the BATSE Large Area Detectors with roughly 25(sigma) significance in the 15-125 keV range in a single rise or set, a variation by a factor of two of a source having one-tenth the strength of Cygnus X-1 should be detectable within a day. Methods of modeling the background are discussed which will increase the accuracy, sensitivity, and reliability of the results beyond those obtainable from a linear background fit with a single rise or set discontinuity.

DXS10011: studies on structure, allele distribution in three populations and genetic linkage to further q-telomeric chromosome X markers.

PubMed

Hering, Sandra; Brundirs, Nicola; Kuhlisch, Eberhard; Edelmann, Jeanett; Plate, Ines; Benecke, Mark; Van, Pham Hung; Michael, Matthias; Szibor, Reinhard

2004-12-01

The hypervariable tetranucleotide STR polymorphism DXS10011 is a powerful marker for forensic purposes. Investigation of this STR led to an allele nomenclature which is in consensus with the ISFG recommendations. DXS10011 is located at Xq28 and genetically closely linked to DXS7423 and DXS8377 but is unlinked to HPRTB and more distant X-chromosomal STRs. DXS10011 is a very complex marker exhibiting some structural variants within alleles of identical length. Two types of repeat structure (regular and inter-alleles) are known and described as types A and B. Two SNPs which are in strong linkage disequilibrium to the different sequence types were found in the repeat flanking region. The type A sequence consists of a long stretch of uninterrupted homogenous repeats which is highly susceptible to slippage mutation during male meiosis.

Meta-analysis of efficacy and safety of apixaban and uninterrupted apixaban therapy compared to vitamin K antagonists in patients undergoing catheter ablation for atrial fibrillation.

PubMed

Ukaigwe, Anene; Shrestha, Pragya; Karmacharya, Paras; Hussain, Sarah K; Samii, Soraya; Gonzalez, Mario D; Wolbrette, Deborah; Naccarrelli, Gerald V

2017-03-01

Apixaban is a Factor Xa inhibitor increasingly being used for stroke prevention in atrial fibrillation (AF). Although several studies have been done, the efficacy and safety of apixaban during the peri-procedural period of AF ablation remains unclear. We sought to systematically review pooled data from these various studies to evaluate thromboembolic and bleeding risks in patients undergoing catheter ablation for AF who are treated with apixaban (interrupted and uninterrupted). Studies comparing anticoagulation with apixaban or vitamin K antagonists (VKA) in patients undergoing ablation for AF were identified via an electronic search of MEDLINE, EMBASE, clinical trials.gov, and Cochrane Library from inception to January 2016. Study-specific risk ratios were calculated and combined with a fixed-effects model meta-analysis. In the analysis of 2100 pooled patients, thromboembolic complications (TE) occurred in 14/778 (1.80 %) patients in the apixaban group (AG) compared to 20/1322 patients in the VKA group (RR 1.03, 95 % CI 0.55-1.90, p = 0.93, I 2  = 0 %). Major bleeding occurred in 9/778 (1.2 %) of the AG compared to 20/1322 (1.51 %) in the VKA group (RR 1.03, 95 % CI 0.55-1.90, p = 0.93, I 2  = 0 %). In uninterrupted apixaban group (uAG), TE occurred in 4/585 (0.68 %) patients in the uAG compared to 6/910 (0.66 %) in VKA group (RR 0.86, 95 % CI 0.25-2.95, p = 0.81, I 2  = 0 %). Major bleeding occurred in 5/585 (0.85 %) in uAG compared to 7/910 (0.77 %) in the VKA group (RR 1.20, 95 % CI 0.37-3.88, p = 0.76, I 2  = 0 %). Our study demonstrates patients treated with apixaban and VKA during the peri-procedural period for AF ablation have similar rates of TE and bleeding complications. Interrupted and uninterrupted apixaban strategies were associated with similar outcomes.

Space Shuttle Projects

NASA Image and Video Library

1988-01-01

This artist's concept drawing depicts the Tracking and Data Relay Satellite-C (TDRS-C), which was the primary payload of the Space Shuttle Discovery on the STS-26 mission, launched on September 29, 1988. The TDRS system provides almost uninterrupted communications with Earth-orbiting Shuttles and satellites, and had replaced the intermittent coverage provided by globe-encircling ground tracking stations used during the early space program. The TDRS can transmit and receive data, and track a user spacecraft in a low Earth orbit. The deployment of TDRS-G on the STS-70 mission being the latest in the series, NASA has successfully launched six TDRSs.

System Developed for Real-Time Blade-Flutter Monitoring in the Wind Tunnel

NASA Technical Reports Server (NTRS)

Kurkov, Anatole P.; Dhadwal, Harbans S.; Radzikowski, mark; Strukov, Dmitri

2005-01-01

A real-time system has been developed to monitor flutter vibrations in turbomachinery. The system is designed for continuous processing of blade tip timing data at a rate of 10 MB/sec. A USB 2.0 interface provides uninterrupted real-time processing of the data, and the blade-tip arrival times are measured with a 50-MHz oscillator and a 24-bit pipelined architecture counter. The input stage includes a glitch catcher, which reduces the probability of detecting a ghost blade to negligible levels. A graphical user interface provides online interrogation of any blade tip from any light probe sensor. Alternatively, data from all blades and all sensors can be superimposed into a single composite scatter plot displaying the vibration amplitude of each blade.

The Main Transport System in the Wheat Ear

NASA Technical Reports Server (NTRS)

Stieber, Joseph; Stieber, Joli; Bubenheim, David L.; Kliss, Mark (Technical Monitor)

1996-01-01

The vascular system in the rachis, rachilla, and florets of the wheat ear was studied by direct microscopical observation of cleaned semi longitudinal sections. A periodic repetitive change of amphivasal and collateral phases was found along each main vascular bundle in the rachis. This change alternates between the two groups of main bundles and is related to the bilateral alternate arrangement of the spikelets on the rachis, so that a large amphivasal phase of the one group opposes the collateral phase of the other group. Ring-shaped tracheary inter-connections were observed mostly at the nodes. A similar system was found in the rachilla. There is a continuous uninterrupted tracheary connection between each of the florets and the rachis. A functional significance of the periodic changes observed has been suggested.

Ukpik: testbed for a miniaturized robotic astronomical observatory on a high Arctic mountain

NASA Astrophysics Data System (ADS)

Steinbring, Eric; Leckie, Brian; Hardy, Tim; Caputa, Kris; Fletcher, Murray

2012-09-01

Mountains along the northwestern coast of Ellesmere Island, Canada, possess the highest peaks nearest the Pole. This geography, combined with an atmospheric thermal inversion restricted to below ~1000 m during much of the long arctic night, provides excellent opportunities for uninterrupted cloud-free astronomy - provided the challenges of these incredibly remote locations can be overcome. We present a miniaturized robotic observatory for deployment on a High Arctic mountaintop. This system tested the operability of precise optical instruments during winter, and the logistics of installation and maintenance during summer. It is called Ukpik after the Inuktitut name for the snowy owl, and was deployed at two sites accessible only by helicopter, each north of 82 degrees latitude; one on rock at 1100 m elevation and another on a glacier at 1600 m. The instrument suite included at first an all-sky-viewing camera, with the later addition of a small telescope to monitor Polaris, both protected by a retractable weather-proof enclosure. Expanding this to include a narrow-field drift-scanning camera for studying extra-solar planet transits was also investigated, but not implemented. An unique restriction was that all had to be run on batteries recharged primarily by a wind turbine. Supplementary power came from a methanol fuel-cell electrical generator. Communications were via the Iridium satellite network. The system design, and lessons learned from three years of operation are discussed, along with prospects for time-domain astronomy from isolated, high-elevation polar mountaintops.

Nucleic acid nanomaterials: Silver-wired DNA

NASA Astrophysics Data System (ADS)

Auffinger, Pascal; Ennifar, Eric

2017-10-01

DNA double helical structures are supramolecular assemblies that are typically held together by classical Watson-Crick pairing. Now, nucleotide chelation of silver ions supports an extended silver-DNA hybrid duplex featuring an uninterrupted silver array.

Survey of the capacity for essential surgery and anaesthesia services in Papua New Guinea

PubMed Central

Martin, Janet; Tau, Goa; Cherian, Meena Nathan; Vergel de Dios, Jennifer; Mills, David; Fitzpatrick, Jane; Adu-Krow, William; Cheng, Davy

2015-01-01

Objective To assess capacity to provide essential surgical services including emergency, obstetric and anaesthesia care in Papua New Guinea (PNG) in order to support planning for relevant post-2015 sustainable development goals for PNG. Design Cross-sectional survey. Setting Hospitals and health facilities in PNG. Participants 21 facilities including 3 national/provincial hospitals, 11 district/rural hospitals, and 7 health centres. Outcome measures The WHO Situational Analysis Tool to Assess Emergency and Essential Surgical Care (WHO-SAT) was used to measure each participating facility's capacity to deliver essential surgery and anaesthesia services, including 108 items related to relevant infrastructure, human resources, interventions and equipment. Results While major surgical procedures were provided at each hospital, fewer than 30% had uninterrupted access to oxygen, and 57% had uninterrupted access to resuscitation bag and mask. Most hospitals reported capacity to provide general anaesthesia, though few hospitals reported having at least one certified surgeon, obstetrician and anaesthesiologist. Access to anaesthetic machines, pulse oximetry and blood bank was severely limited. Many non-hospital health centres providing basic surgical procedures, but almost none had uninterrupted access to electricity, running water, oxygen and basic supplies for resuscitation, airway management and obstetric services. Conclusions Capacity for essential surgery and anaesthesia services is severely limited in PNG due to shortfalls in physical infrastructure, human resources, and basic equipment and supplies. Achieving post-2015 sustainable development goals, including universal healthcare, will require significant investment in surgery and anaesthesia capacity in PNG. PMID:26674504

Development status of a sealed bipolar lead/acid battery for high-power battery applications

NASA Astrophysics Data System (ADS)

Arias, J. L.; Rowlette, J. J.; Drake, E. D.

A sealed bipolar lead/acid (SBLA) battery is being developed by Arias Research Associates (ARA) which will offer a number of important advantages in applications requiring high power densities. These applications include electric vehicles (EVs) and hybrid electric vehicles, uninterruptable power supplies (UPS), electrically-heated catalysts (EHCs) for automobiles, utility-power peak-shaving, and others. The advantages of the SBLA over other types of batteries will by significantly higher power density, together with good energy density, high cycle life, high voltage density, low production cost and zero maintenance. In addition, the lead/acid battery represents a technology which is familiar and accepted by Society, is recyclable within the existing infrastructure, and does not raise the safety concerns of many other new batteries (e.g., fire, explosion and toxic gases). This paper briefly reviews the basic design concepts and issues of the SBLA battery technology, various quasi-bipolar approaches and the results of ARA's development work during the past four years. Performance data are given based on both in-house and independent testing of ARA laboratory test batteries. In addition, performance projections and other characteristics are given for three ARA SBLA battery designs, which are compared with other batteries in three example applications: UPS, EHCs, and EVs. The most notable advantages of the SBLA battery are substantial reductions in product size and weight for the UPS, smaller packaging and longer life for the EHC, and higher vehicle performance and lower cost for the EV, compared to both existing and advanced EV batteries.

A "Do-It-Yourself" phenotyping system: measuring growth and morphology throughout the diel cycle in rosette shaped plants.

PubMed

Dobrescu, Andrei; Scorza, Livia C T; Tsaftaris, Sotirios A; McCormick, Alistair J

2017-01-01

Improvements in high-throughput phenotyping technologies are rapidly expanding the scope and capacity of plant biology studies to measure growth traits. Nevertheless, the costs of commercial phenotyping equipment and infrastructure remain prohibitively expensive for wide-scale uptake, while academic solutions can require significant local expertise. Here we present a low-cost methodology for plant biologists to build their own phenotyping system for quantifying growth rates and phenotypic characteristics of Arabidopsis thaliana rosettes throughout the diel cycle. We constructed an image capture system consisting of a near infra-red (NIR, 940 nm) LED panel with a mounted Raspberry Pi NoIR camera and developed a MatLab-based software module (iDIEL Plant) to characterise rosette expansion. Our software was able to accurately segment and characterise multiple rosettes within an image, regardless of plant arrangement or genotype, and batch process image sets. To further validate our system, wild-type Arabidopsis plants (Col-0) and two mutant lines with reduced Rubisco contents, pale leaves and slow growth phenotypes ( 1a3b and 1a2b ) were grown on a single plant tray. Plants were imaged from 9 to 24 days after germination every 20 min throughout the 24 h light-dark growth cycle (i.e. the diel cycle). The resulting dataset provided a dynamic and uninterrupted characterisation of differences in rosette growth and expansion rates over time for the three lines tested. Our methodology offers a straightforward solution for setting up automated, scalable and low-cost phenotyping facilities in a wide range of lab environments that could greatly increase the processing power and scalability of Arabidopsis soil growth experiments.

Miniature Biometric Sensor Project

NASA Technical Reports Server (NTRS)

Falker, John; Terrier, Douglas; Clayton, Ronald; Hanson, Andrea; Cooper, Tommy; Downs, Meghan; Flint, Stephanie; Reyna, Baraquiel; Simon, Cory; Wilt, Grier

2015-01-01

Heart rate monitoring (HRM) is a critical need during exploration missions. Unlike the four separate systems used on ISS today, the single HRM system should perform as a diagnostic tool, perform well during exercise or high level activity, and be suitable for use during EVA. Currently available HRM technologies are dependent on uninterrupted contact with the skin and are prone to data drop-out and motion artifact when worn in the spacesuit or during exercise. Here, we seek an alternative to the chest strap and electrode based sensors currently in use on ISS today. This project aims to develop a single, high performance, robust biosensor with focused efforts on improved heart rate data quality collection during high intensity activity such as exercise or EVA.

77 FR 16927 - Drawbridge Operation Regulation; Willamette River, Portland, OR

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-23

..., mile 11.7, at Portland, OR. This deviation is necessary to accommodate the Race for the Roses event... to facilitate safe, uninterrupted roadway passage of participants of the Race for the Roses event...

77 FR 26437 - Drawbridge Operation Regulation; Willamette River, Portland, OR

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-04

... deviation is necessary to accommodate the May 2012 running of Portland's Rock-n-Roll Half Marathon. This..., uninterrupted roadway passage of participants of the Rock-n-Roll Half Marathon event. The Hawthorne Bridge...

Technique for joining metal tubing

NASA Technical Reports Server (NTRS)

Wright, H. W.

1976-01-01

Uniform wall thickness and uninterrupted heat transfer is achieved by using shaped metal insert as wall material for joint. Insert acts as support during brazing, after which excess material is ground away to bring joint to original tubing size.

78 FR 15879 - Drawbridge Operation Regulation; Willamette River, Portland, OR

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-13

.... This deviation is necessary to accommodate the Race for the Roses and the Bridge to Brews Run [[Page... facilitate safe, uninterrupted roadway passage of participants in the Race for the Roses and the Bridge to...

A Case of Bilateral Pigment Dispersion Syndrome Following Many Years of Uninterrupted Treatment With Atropine 1% for Bilateral Congenital Cataracts.

PubMed

Gizzi, Corrado; Mohamed-Noriega, Jibran; Murdoch, Ian

2017-10-01

Describe an unusual case of bilateral pigment dispersion syndrome (PDS) following years of uninterrupted treatment with atropine 1% for bilateral congenital cataracts, speculate on potential mechanisms leading to this condition. This is a case report. A 45-year-old white patient on long-term treatment with atropine 1% ointment since his infancy for bilateral congenital cataracts developed PDS with secondary ocular hypertension. The patient showed all the hallmarks of PDS with secondary ocular hypertension. An anterior segment Swept-Source optical coherence tomography was obtained to review the iris profile. The patient showed good pressure response to topical prostaglandin therapy. This is the second case report of PDS in a patient with chronic use of topical atropine. The proposed mechanisms for pigment dispersion are discussed and the possibility raised of dispersion being a potential side effect of the drug.

The effects of bilateral stimulation of the subthalamic nucleus on heart rate variability in patients with Parkinson's disease.

PubMed

Liu, Kang-Du; Shan, Din-E; Kuo, Terry B J; Yang, Cheryl C H

2013-07-01

The beneficial effects of subthalamic nucleus deep brain stimulation (STN-DBS) on motor symptoms and quality of life in Parkinson's disease (PD) are well known, but little is known of the effects on autonomic function. Diffusion of current during stimulation of the STN may simultaneously involve the motor and nonmotor, limbic and associative areas of the STN. The aims of this study were to examine whether STN stimulation affects functions of the autonomic nervous system and, if so, to correlate the effects with the active contacts of electrodes in the STN. Eight PD patients with good motor control and quality of sleep after STN-DBS surgery were recruited. All patients had two days of recordings with portable polysomnography (PSG) (first night with stimulation "on" and second night "off"). From the PSG data, the first sleep cycle of each recording night was defined. Heart rate variability (HRV) was analyzed between the same uninterrupted periods of the two sleep nights. In addition, the optimal electrode positions were defined from postoperative MRI studies, and the coordinates of active contacts were confirmed. HRV spectral analysis showed that only low-frequency (LF)/high-frequency (HF) power was significantly activated in the stimulation "on" groups (P = 0.011). There was a significant negative correlation between power change of LF/HF and electrode position lateral to the midcommissural point (ρ = 0.857, P = 0.007) These results demonstrate that STN-DBS can enhance sympathetic regulation; the autonomic response may be due to electrical signals being distributed to limbic components of the STN or descending sympathetic pathways in the zona incerta.

Telemedicine in pediatric cardiac critical care.

PubMed

Munoz, Ricardo A; Burbano, Nelson H; Motoa, María V; Santiago, Gabriel; Klevemann, Matthew; Casilli, Jeanne

2012-03-01

To describe our international telemedicine experience in pediatric cardiac critical care. This is a case series of pediatric patients teleassisted from the Cardiac Intensive Care Unit (CICU) at Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, PA, to the CICU at Hospital Valle del Lili, Cali, Valle, Colombia, between March and December 2010. An attending intensivist from the CICU in Pittsburgh reviewed cases, monitored real-time vital signs, and gave formal medical advice as requested by the attending physician in Cali. The network connection is a Cisco (San Jose, CA)-based Secure Sockets Layer virtual private network via the Internet that allows access to the web-based interface of the Dräger(®) (Lübeck, Germany) physiological monitor system. The videoconferencing equipment consists of a standard component on a custom-made mobile cart that uses an APC(®) (West Kingston, RI) uninterruptible power supply for portable power and 3Com(®) (Hewlett-Packard, Palo Alto, CA) for wireless connectivity. A post-intervention survey regarding satisfaction with the telemedicine service was conducted. Seventy-one recommendations were given regarding 53 patients. Median age and weight were 10 months and 7.1 kg, respectively. Ventricular septal defect, transposition of the great vessels, and single ventricle accounted for most cases. The most frequent recommendations were related to surgical conduct, management of arrhythmias, and performance of cardiac catheterization studies. No technical difficulties were experienced during the monitoring of the patients. Satisfaction rates were equally high for technical and medical aspects of telemedicine service. Telemedicine is a feasible option for pediatric intensivists seeking experienced assistance in the management of complex cardiac patients. Real-time remote assistance may improve the medical care of pediatric cardiac patients treated in developing countries.

Quantifying the Impact of Unavailability in Cyber-Physical Environments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aissa, Anis Ben; Abercrombie, Robert K; Sheldon, Federick T.

2014-01-01

The Supervisory Control and Data Acquisition (SCADA) system discussed in this work manages a distributed control network for the Tunisian Electric & Gas Utility. The network is dispersed over a large geographic area that monitors and controls the flow of electricity/gas from both remote and centralized locations. The availability of the SCADA system in this context is critical to ensuring the uninterrupted delivery of energy, including safety, security, continuity of operations and revenue. Such SCADA systems are the backbone of national critical cyber-physical infrastructures. Herein, we propose adapting the Mean Failure Cost (MFC) metric for quantifying the cost of unavailability.more » This new metric combines the classic availability formulation with MFC. The resulting metric, so-called Econometric Availability (EA), offers a computational basis to evaluate a system in terms of the gain/loss ($/hour of operation) that affects each stakeholder due to unavailability.« less

Physical Origins of Space Weather Impacts: Open Physics Questions

NASA Astrophysics Data System (ADS)

Lanzerotti, L. J.

2011-12-01

Beginning with the era of development of electrical telegraph systems in the early 19th century, physical processes in the space environment on the Sun, in the interplanetary medium, and around Earth have influenced the design and operations of ever-increasing and sophisticated technical systems, both in space and on the ground. Understanding of Earth's space environment has increased enormously in the last century and one-half. Nevertheless, many of the physical processes that produced effects on early cable and wireless technologies continue to plague modern-day systems. And as new technologies are developed for improved communications, surveillance, navigation, and conditions for human space flight, the solar-terrestrial environment often offers surprises to their safe, secure and uninterrupted operations. This talk will address some of the challenges that I see to the successful operations of some modern-day technical systems that are posed by significant deficiencies of understanding of physical processes operating from the Sun to the Earth.

Space industrialization. [space flight and environment for commercial/utilitarian purposes

NASA Technical Reports Server (NTRS)

Disher, J. H.

1977-01-01

Space industrialization is defined as the use of space flight and the space environment for commercial or utilitarian purposes in contrast to other uses such as gains in basic scientific knowledge, national defense, or exploration. Some unique attributes of space that make it amenable to industrial use include overview of the earth, the 'zero gravity' effect, potential for near perfect vacuum, unlimited reservoir for disposal of waste products, availability of essentially uninterrupted flow of solar energy, and the 'perpetual motion' characteristic of orbital mechanics. The role of human participation in assembling and maintaining the large sophisticated systems that will be required for future space industrialization needs is considered.

Efficacy and Safety of Uninterrupted Low-Intensity Warfarin for Radiofrequency Catheter Ablation of Atrial Fibrillation in the Elderly.

PubMed

Xing, Yangbo; Xu, Buyun; Xu, Chao; Peng, Fang; Yang, Biao; Qiu, Yufang; Sun, Yong; Wang, Shengkai; Guo, Hangyuan

2017-09-01

No previous studies exist investigating the optimal intensity of uninterrupted anticoagulation with warfarin during radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF) in the elderly. Evaluate the efficacy and safety of continuous low-intensity warfarin therapy throughout the periprocedural period of RFCA for AF in the elderly. This is a prospective randomized study. We enrolled AF patients (age ≥ 70 years) who underwent first-time RFCA for AF. Enrolled patients were randomized to group A and group B. The international normalized ratios before ablation were maintained at 1.5 to 2.0 and 2.0 to 2.5 in group A and B, respectively. Primary end points were periprocedural thromboembolic complications and major bleeding. Secondary end points included periprocedural asymptomatic cerebral emboli (ACE) and minor bleeding. A total of 101 patients were enrolled in our study (group A: 52; group B: 49). Baseline characteristics were well balanced between the 2 groups. Only 1 patient suffered from stroke in group B. No major bleeding events occurred in either group. The incidence of new ACE lesions was comparable between the 2 groups (11.5% vs 8.2%, P = 0.82). Minor bleeding occurred in 1 of 52 (1.9%) patients in group A and in 5 of 49 (10.2%) patients in group B ( P = 0.10). Uninterrupted low-intensity warfarin for RFCA of AF might be as effective as standard-intensity warfarin in preventing periprocedural thromboembolic complications and might be associated with fewer bleeding events in the elderly.

Use of a pocket compression device for the prevention and treatment of pocket hematoma after pacemaker and defibrillator implantation (STOP-HEMATOMA-I).

PubMed

Turagam, Mohit K; Nagarajan, Darbhamulla V; Bartus, Krzysztof; Makkar, Akash; Swarup, Vijay

2017-08-01

Pocket hematoma is a recognized complication after placement of cardiac implantable electronic devices and is associated with increased device infection, length of hospitalization, and morbidity especially with uninterrupted antiplatelet agents and anticoagulants. We assessed the use of a post-surgical vest to decrease the incidence of pocket hematoma in patients undergoing device implantation with uninterrupted antiplatelet and anticoagulants. In this observational study, a vest was used by 20 consecutive patients who were compared to 20 age-, gender-, procedure-matched patients who received standard care. All patients were continued on antiplatelet and anticoagulants in the perioperative period. The pocket was assessed at post procedure day 0, 2, and 7, respectively. There were no significant differences in the baseline characteristics between both groups. Baseline mean international normalized ratio (INR) was significantly higher in the vest group when compared with the control group (2.7 ± 0.4 vs. 2.2 ± 0.3 = <0.001). The incidence of pocket hematoma was significantly lower in the vest group than the control group (0 vs 30%, p = 0.02) at the end of 7 days. Control group had a total of six hematomas with one patient requiring evacuation and blood transfusion. The vest group had three hematomas on day 2 that resolved by day 7. The risk of moderate or large pocket hematoma is significantly reduced with the use of this vest in high-risk patients undergoing implantable devices on uninterrupted antiplatelet and anticoagulants.

Survey of the capacity for essential surgery and anaesthesia services in Papua New Guinea.

PubMed

Martin, Janet; Tau, Goa; Cherian, Meena Nathan; Vergel de Dios, Jennifer; Mills, David; Fitzpatrick, Jane; Adu-Krow, William; Cheng, Davy

2015-12-16

To assess capacity to provide essential surgical services including emergency, obstetric and anaesthesia care in Papua New Guinea (PNG) in order to support planning for relevant post-2015 sustainable development goals for PNG. Cross-sectional survey. Hospitals and health facilities in PNG. 21 facilities including 3 national/provincial hospitals, 11 district/rural hospitals, and 7 health centres. The WHO Situational Analysis Tool to Assess Emergency and Essential Surgical Care (WHO-SAT) was used to measure each participating facility's capacity to deliver essential surgery and anaesthesia services, including 108 items related to relevant infrastructure, human resources, interventions and equipment. While major surgical procedures were provided at each hospital, fewer than 30% had uninterrupted access to oxygen, and 57% had uninterrupted access to resuscitation bag and mask. Most hospitals reported capacity to provide general anaesthesia, though few hospitals reported having at least one certified surgeon, obstetrician and anaesthesiologist. Access to anaesthetic machines, pulse oximetry and blood bank was severely limited. Many non-hospital health centres providing basic surgical procedures, but almost none had uninterrupted access to electricity, running water, oxygen and basic supplies for resuscitation, airway management and obstetric services. Capacity for essential surgery and anaesthesia services is severely limited in PNG due to shortfalls in physical infrastructure, human resources, and basic equipment and supplies. Achieving post-2015 sustainable development goals, including universal healthcare, will require significant investment in surgery and anaesthesia capacity in PNG. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Hydrogen Cyanide Related Deaths and Detection in the Blood

DTIC Science & Technology

2012-01-01

elevations in creatinine , glucose, and bilirubin have been reported, as have decrease alanine aminotransferase, and unpredictable results for... creatine phosphokinase, phosphate, and lactate dehydrogenase [4]. Urinalyses are often uninterruptable [3]. Thus, we are concerned that deceased patients

Note: control of liquid helium supply to cryopanels of Kolkata superconducting cyclotron.

PubMed

Bhattacharyya, T K; Pal, G

2015-02-01

The Kolkata superconducting cyclotron utilises liquid helium to cool the main magnet niobium-titanium (NbTi) coil and the cryopanels. Three liquid helium cooled cryopanels, placed inside the dees of the radio-frequency system, maintain the high vacuum in the acceleration region of the superconducting cyclotron. The small cryostat placed inside the cryogenic distribution manifold located at the basement of the superconducting cyclotron building supplies liquid helium in parallel branches to three cold heads, used for cooling their associated cryopanels. The level in the cryostat has to be maintained at an optimum value to ensure uninterrupted flow of liquid helium to these three cold heads. This paper describes the transfer function of the overall system, its tuning parameters, and discusses the actual control of cryostat level by using these parameters.

June 2017 Ancho Canyon RF Collects: Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Junor, William; Layne, John Preston; Goglio, Joshua Henry

2017-09-21

We report the results from the June 8, 2017, Ancho Canyon RF collection. While bright, electromagnetic signals were seen close to the firing point, there were no detections of signals from the explosively-fired fuse (EFF) at a collection point about 600m distant on the East Mesa. The East Mesa site was unable to collect data because the uninterruptible power supply (UPS) was exhausted by the time of the shot. We did see signals from the EFF at the Bunker 57 antennas, about 123m distant from the Point 88 firing point. The strength of these signals is consistent with our limitedmore » knowledge of the collection antenna performance and the use of the standard model to predict the electric field strength. From our knowledge of the geometry of the EFF loop and the current in the loop in this test, and from measurements at the Bunker 57 site, we predict that we would have seen signals of about 50mV at 3.67MHz in a 100 kHz channel on the Rohde & Schwarz HE010 antennas at the East Mesa location. The noise oor there is about 0.113mV (based on the March 2017 collects). Thus we would have had an SNR of 53 dB from the collect, had the data collection system been running.« less

Caring for Ourselves.

ERIC Educational Resources Information Center

Besculides, George

1999-01-01

A Long Island superintendent (a former workaholic) explains his need for relaxation, uninterrupted family time, and behavior changes. He now takes all of his vacation time (without calling the office), delegates authority, and relaxes off the job. Superintendents are empowered to control their own wellness. (MLH)

Gigabit Wireless for Network Connectivity

ERIC Educational Resources Information Center

Schoedel, Eric

2009-01-01

Uninterrupted, high-bandwidth network connectivity is crucial for higher education. Colleges and universities increasingly adopt gigabit wireless solutions because of their fiber-equivalent performance, quick implementation, and significant return on investment. For just those reasons, Rush University Medical Center switched from free space optics…

Goals and strategies in the global control design of the OAJ Robotic Observatory

NASA Astrophysics Data System (ADS)

Yanes-Díaz, A.; Rueda-Teruel, S.; Antón, J. L.; Rueda-Teruel, F.; Moles, M.; Cenarro, A. J.; Marín-Franch, A.; Ederoclite, A.; Gruel, N.; Varela, J.; Cristóbal-Hornillos, D.; Chueca, S.; Díaz-Martín, M. C.; Guillén, L.; Luis-Simoes, R.; Maícas, N.; Lamadrid, J. L.; López-Sainz, A.; Hernández-Fuertes, J.; Valdivielso, L.; Mendes de Oliveira, C.; Penteado, P.; Schoenell, W.; Kanaan, A.

2012-09-01

There are many ways to solve the challenging problem of making a high performance robotic observatory from scratch. The Observatorio Astrofísico de Javalambre (OAJ) is a new astronomical facility located in the Sierra de Javalambre (Teruel, Spain) whose primary role will be to conduct all-sky astronomical surveys. The OAJ control system has been designed from a global point of view including astronomical subsystems as well as infrastructures and other facilities. Three main factors have been considered in the design of a global control system for the robotic OAJ: quality, reliability and efficiency. We propose CIA (Control Integrated Architecture) design and OEE (Overall Equipment Effectiveness) as a key performance indicator in order to improve operation processes, minimizing resources and obtaining high cost reduction whilst maintaining quality requirements. The OAJ subsystems considered for the control integrated architecture are the following: two wide-field telescopes and their instrumentation, active optics subsystems, facilities for sky quality monitoring (seeing, extinction, sky background, sky brightness, cloud distribution, meteorological station), domes and several infrastructure facilities such as water supply, glycol water, water treatment plant, air conditioning, compressed air, LN2 plant, illumination, surveillance, access control, fire suppression, electrical generators, electrical distribution, electrical consumption, communication network, Uninterruptible Power Supply and two main control rooms, one at the OAJ and the other remotely located in Teruel, 40km from the observatory, connected through a microwave radio-link. This paper presents the OAJ strategy in control design to achieve maximum quality efficiency for the observatory processes and operations, giving practical examples of our approach.

Challenges and opportunities of integration of community based Management of Acute Malnutrition into the government health system in Bangladesh: a qualitative study.

PubMed

Ireen, Santhia; Raihan, Mohammad Jyoti; Choudhury, Nuzhat; Islam, M Munirul; Hossain, Md Iqbal; Islam, Ziaul; Rahman, S M Mustafizur; Ahmed, Tahmeed

2018-04-10

Severe acute malnutrition (SAM) in children is the most serious form of malnutrition and is associated with very high rates of morbidity and mortality. For sustainable SAM management, United Nations recommends integration of community based management of acute malnutrition (CMAM) into the health system. The objective of the study was to assess the preparedness of the health system to implement CMAM in Bangladesh. The assessment was undertaken during January to May 2014 by conducting document review, key informant interviews, and direct observation. A total of 38 key informant interviews were conducted among government policy makers and program managers (n = 4), nutrition experts (n = 2), health and nutrition implementing partners (n = 2), development partner (n = 1), government health system staff (n = 5), government front line field workers (n = 22), and community members (n = 2). The assessment was based on: workforce, service delivery, financing, governance, information system, medical supplies, and the broad socio-political context. The government of Bangladesh has developed inpatient and outpatient guidelines for the management of SAM. There are cadres of community health workers of government and non-government actors who can be adequately trained to conduct CMAM. Inpatient management of SAM is available in 288 facilities across the country. However, only 2.7% doctors and 3.3% auxiliary staff are trained on facility based management of SAM. In functional facilities, uninterrupted supply of medicines and therapeutic diet are not available. There is resistance and disagreement among nutrition stakeholders regarding import or local production of ready-to-use therapeutic food (RUTF). Nutrition coordination is fragile and there is no functional supra-ministerial coordination platform for multi-sectoral and multi-stakeholder nutrition. There is an enabling environment for CMAM intervention in Bangladesh although health system strengthening is needed considering the barriers that have been identified. Training of facility based health staff, government community workers, and ensuring uninterrupted supply of medicines and logistics to the functional facilities should be the immediate priorities. Availability of ready-to-use therapeutic food (RUTF) is a critical component of CMAM and government should promote in-country production of RUTF for effective integration of CMAM into the health system in Bangladesh.

Photoemission experiments of a large area scandate dispenser cathode

NASA Astrophysics Data System (ADS)

Zhang, Huang; Liu, Xing-guang; Chen, Yi; Chen, De-biao; Jiang, Xiao-guo; Yang, An-min; Xia, Lian-sheng; Zhang, Kai-zhi; Shi, Jin-shui; Zhang, Lin-wen

2010-09-01

A 100-mm-diameter scandate dispenser cathode was tested as a photocathode with a 10 ns Nd:YAG laser (266 nm) on an injector test stand for linear induction accelerators. This thermionic dispenser cathode worked at temperatures ranging from room temperature to 930 °C (below or near the thermionic emission threshold) while the vacuum was better than 4×10 -7 Torr. The laser pulse was synchronized with a 120 ns diode voltage pulse stably and they were in single pulse mode. Emission currents were measured by a Faraday cup. The maximum peak current collected at the anode was about 100 A. The maximum quantum efficiency measured at low laser power was 2.4×10 -4. Poisoning effect due to residual gas was obvious and uninterrupted heating was needed to keep cathode's emission capability. The cathode was exposed to air one time between experiments and recovered after being reconditioned. Photoemission uniformity of the cathode was also explored by changing the laser spot's position.

Lunar oxygen and metal for use in near-Earth space: Magma electrolysis

NASA Technical Reports Server (NTRS)

Colson, Russell O.; Haskin, Larry A.

1990-01-01

Because it is energetically easier to get material from the Moon to Earth orbit than from the Earth itself, the Moon is a potentially valuable source of materials for use in space. The unique conditions on the Moon, such as vacuum, absence of many reagents common on the Earth, and the presence of very nontraditional ores suggest that a unique and nontraditional process for extracting materials from the ores may prove the most practical. With this in mind, an investigation of unfluxed silicate electrolysis as a method for extracting oxygen, iron, and silicon from lunar regolith was initiated and is discussed. The advantages of the process include simplicity of concept, absence of need to supply reagents from Earth, and low power and mass requirements for the processing plant. Disadvantages include the need for uninterrupted high temperature and the highly corrosive nature of the high-temperature silicate melts which has made identifying suitable electrode and container materials difficult.

Valving for controlling a fluid-driven reciprocating apparatus

DOEpatents

Whitehead, John C.

1995-01-01

A pair of control valve assemblies for alternately actuating a pair of fluid-driven free-piston devices by using fluid pressure communication therebetween. Each control valve assembly is switched by a pressure signal depending on the state of its counterpart's piston. The communication logic is arranged to provide overlap of the forward strokes of the pistons, so that at least one of the pair will always be pressurized. Thus, uninterrupted pumping of liquid is made possible from a pair of free-piston pumps. In addition, the speed and frequency of piston stroking is entirely dependent on the mechanical power load applied. In the case of a pair of pumps, this enables liquid delivery at a substantially constant pressure over the full range of flow rates, from zero to maximum flow. Each of the valve assemblies uses an intake-exhaust valve and a signal valve with the signal valve of one pump being connected to be pressure responsive to the piston of the opposite cylinder or pump.

Valving for controlling a fluid-driven reciprocating apparatus

DOEpatents

Whitehead, J.C.

1995-06-27

A pair of control valve assemblies is described for alternately actuating a pair of fluid-driven free-piston devices by using fluid pressure communication therebetween. Each control valve assembly is switched by a pressure signal depending on the state of its counterpart`s piston. The communication logic is arranged to provide overlap of the forward strokes of the pistons, so that at least one of the pair will always be pressurized. Thus, uninterrupted pumping of liquid is made possible from a pair of free-piston pumps. In addition, the speed and frequency of piston stroking is entirely dependent on the mechanical power load applied. In the case of a pair of pumps, this enables liquid delivery at a substantially constant pressure over the full range of flow rates, from zero to maximum flow. Each of the valve assemblies uses an intake-exhaust valve and a signal valve with the signal valve of one pump being connected to be pressure responsive to the piston of the opposite cylinder or pump. 15 figs.

48 CFR 22.101-1 - General.

Code of Federal Regulations, 2011 CFR

2011-10-01

... agencies to ensure a uniform Government approach concerning a particular plant or labor-management dispute... management and labor, notwithstanding the continuance of the dispute, to permit uninterrupted acquisition of... between labor and contractor management and not undertake the conciliation, mediation, or arbitration of a...

Implementation of automatic sign inventory and pavement condition evaluation on Georgia's interstate highways : final report.

DOT National Transportation Integrated Search

2017-02-01

Traffic signs and pavements are indispensable assets to facilitate safe and uninterrupted travel. Manual methods are used for both traffic sign inventory and pavement condition evaluation by the Georgia Department of Transportation (GDOT), although t...

Family presence during trauma activations and medical resuscitations in a pediatric emergency department: an evidence-based practice project.

PubMed

Kingsnorth, Jennifer; O'Connell, Karen; Guzzetta, Cathie E; Edens, Jacki Curreri; Atabaki, Shireen; Mecherikunnel, Anne; Brown, Kathleen

2010-03-01

The existing family presence literature indicates that implementation of a family presence policy can result in positive outcomes. The purpose of our evidence-based practice project was to evaluate a family presence intervention using the 6 A's of the evidence cycle (ask, acquire, appraise, apply, analyze, and adopt/adapt). For step 1 (ask), we propose the following question: Is it feasible to implement a family presence intervention during trauma team activations and medical resuscitations in a pediatric emergency department using national guidelines to ensure appropriate family member behavior and uninterrupted patient care? Regarding steps 2 through 4 (acquire, appraise, and apply), our demonstration project was conducted in a pediatric emergency department during the implementation of a new family presence policy. Our family presence intervention incorporated current appraisal of literature and national guidelines including family screening, family preparation, and use of family presence facilitators. We evaluated whether it was feasible to implement the steps of our intervention and whether the intervention was safe in ensuring uninterrupted patient care. With regard to step 5 (analyze), family presence was evaluated in 106 events, in which 96 families were deemed appropriate and chose to be present. Nearly all families (96%) were screened before entering the room, and all were deemed appropriate candidates. Facilitators guided the family during all events. One family presence event was terminated. In all cases patient care was not interrupted. Regarding step 6 (adopt/adapt), our findings document the feasibility of implementing a family presence intervention in a pediatric emergency department while ensuring uninterrupted patient care. We have adopted family presence as a standard practice. This project can serve as the prototype for others. Copyright (c) 2010 Emergency Nurses Association. Published by Mosby, Inc. All rights reserved.

MIMO H∞ control of three-axis ship-mounted mobile antenna systems

NASA Astrophysics Data System (ADS)

Kuseyri, İ. Sina

2018-02-01

The need for on-line information in any environment has led to the development of mobile satellite communication terminals. These high data-rate terminals require inertial antenna pointing error tolerance within fractions of a degree. However, the base motion of the antenna platform in mobile applications complicates this pointing problem and must be accounted for. Gimbaled motorised pedestals are used to eliminate the effect of disturbance and maintain uninterrupted communication. In this paper, a three-axis ship-mounted antenna on a pedestal gimbal system is studied. Based on the derived dynamic model of the antenna pedestal multi input-multi output PID and H∞ linear controllers are designed to stabilise the antenna to keep its orientation unaltered towards the satellite while the sea waves disturb the antenna. Simulation results are presented to show the stabilisation performance of the system with the synthesised controllers. It is shown through performance comparison and analysis that the proposed H∞ control structure is preferable over PID controlled system in terms of system stability and the disturbance rejection.

Metal oxide coating of carbon supports for supercapacitor applications.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boyle, Timothy J.; Tribby, Louis, J; Lakeman, Charles D. E.

2008-07-01

The global market for wireless sensor networks in 2010 will be valued close to $10 B, or 200 M units. TPL, Inc. is a small Albuquerque based business that has positioned itself to be a leader in providing uninterruptible power supplies in this growing market with projected revenues expected to exceed $26 M in 5 years. This project focused on improving TPL, Inc.'s patent-pending EnerPak{trademark} device which converts small amounts of energy from the environment (e.g., vibrations, light or temperature differences) into electrical energy that can be used to charge small energy storage devices. A critical component of the EnerPak{trademark}more » is the supercapacitor that handles high power delivery for wireless communications; however, optimization and miniaturization of this critical component is required. This proposal aimed to produce prototype microsupercapacitors through the integration of novel materials and fabrication processes developed at New Mexico Technology Research Collaborative (NMTRC) member institutions. In particular, we focused on developing novel ruthenium oxide nanomaterials and placed them into carbon supports to significantly increase the energy density of the supercapacitor. These improvements were expected to reduce maintenance costs and expand the utility of the TPL, Inc.'s device, enabling New Mexico to become the leader in the growing global wireless power supply market. By dominating this niche, new customers were expected to be attracted to TPL, Inc. yielding new technical opportunities and increased job opportunities for New Mexico.« less

Evaluation of center-cut separations applying simulated moving bed chromatography with 8 zones.

PubMed

Santos da Silva, Francisco Vitor; Seidel-Morgenstern, Andreas

2016-07-22

Different multi-column options to perform continuous chromatographic separations of ternary mixtures have been proposed in order to overcome limitations of batch chromatography. One attractive option is given by simulated moving bed chromatography (SMB) with 8 zones, a process that offers uninterrupted production, and, potentially, improved economy. As in other established ternary separation processes, the separation sequence is crucial for the performance of the process. This problem is addressed here by computing and comparing optimal performances of the two possibilities assuming linear adsorption isotherms. The conclusions are presented in a decision tree which can be used to guide the selection of system configuration and operation. Copyright © 2016 Elsevier B.V. All rights reserved.

14 CFR 1260.71 - Supplements and renewals.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., continued research relevance, and progress made by the recipient. (2) To insure uninterrupted programs, the technical office should forward to the grant office a completed award package, including a funded procurement request, technical evaluation of the proposed budget, and other support documentation, at least 29...

Apparatus for Direct Optical Fiber Through-Lens Illumination of Microscopy or Observational Objects

NASA Technical Reports Server (NTRS)

Kadogawa, Hiroshi (Inventor)

2001-01-01

In one embodiment of the invention, a microscope or other observational apparatus, comprises a hollow tube, a lens mounted to the tube, a light source and at least one flexible optical fiber having an input end and an output end. The input end is positioned to receive light from the light source, and the output end is positioned within the tube so as to directly project light along a straight path to the lens to illuminate an object to be viewed. The path of projected light is uninterrupted and free of light deflecting elements. By passing the light through the lens, the light can be diffused or otherwise defocused to provide more uniform illumination across the surface of the object, increasing the quality of the image of the object seen by the viewer. The direct undeflected and uninterrupted projection of light, without change of direction, eliminates the need for light-deflecting elements, such as beam-splitters, mirrors, prisms, or the like, to direct the projected light towards the object.

Constructed uninterrupted charge-transfer pathways in three-dimensional micro/nanointerconnected carbon-based electrodes for high energy-density ultralight flexible supercapacitors.

PubMed

He, Yongmin; Chen, Wanjun; Zhou, Jinyuan; Li, Xiaodong; Tang, Pengyi; Zhang, Zhenxing; Fu, Jiecai; Xie, Erqing

2014-01-08

A type of freestanding three-dimensional (3D) micro/nanointerconnected structure, with a conjunction of microsized 3D graphene networks, nanosized 3D carbon nanofiber (CNF) forests, and consequently loaded MnO2 nanosheets, has been designed as the electrodes of an ultralight flexible supercapacitor. The resulting 3D graphene/CNFs/MnO2 composite networks exhibit remarkable flexibility and highly mechanical properties due to good and intimate contacts among them, without current collectors and binders. Simultaneously, this designed 3D micro/nanointerconnected structure can provide an uninterrupted double charges freeway network for both electron and electrolyte ion to minimize electron accumulation and ion-diffusing resistance, leading to an excellent electrochemical performance. The ultrahigh specific capacitance of 946 F/g from cyclic voltammetry (CV) (or 920 F/g from galvanostatic charging/discharging (GCD)) were obtained, which is superior to that of the present electrode materials based on 3D graphene/MnO2 hybrid structure (482 F/g). Furthermore, we have also investigated the superior electrochemical performances of an asymmetric supercapacitor device (weight of less than 12 mg/cm(2) and thickness of ~0.8 mm), showing a total capacitance of 0.33 F/cm(2) at a window voltage of 1.8 V and a maximum energy density of 53.4 W h/kg for driving a digital clock for 42 min. These inspiring performances would make our designed supercapacitors become one of the most promising candidates for the future flexible and lightweight energy storage systems.

Expertise and responsibility effects on pilots' reactions to flight deck alerts in a simulator.

PubMed

Zheng, Yiyuan; Lu, Yanyu; Yang, Zheng; Fu, Shan

2014-11-01

Flight deck alerts provide system malfunction information designed to lead corresponding pilot reactions aimed at guaranteeing flight safety. This study examined the roles of expertise and flight responsibility and their relationship to pilots' reactions to flight deck alerts. There were 17 pilots composing 12 flight crews that were assigned into pairs according to flight hours and responsibilities. The experiment included 9 flight scenarios and was carried out in a CRJ-200 flight simulator. Pilot performance was recorded by a wide angle video camera, and four kinds of reactions to alerts were defined for analysis. Pilots tended to have immediate reactions to uninterrupted cautions, with a turning off rate as high as 75%. However, this rate decreased sharply when pilots encountered interrupted cautions and warnings; they also exhibited many wrong reactions to warnings. Pilots with more expertise had more reactions to uninterrupted cautions than those with less expertise, both as pilot flying and pilot monitoring. Meanwhile, the pilot monitoring, regardless of level of expertise, exhibited more reactions than the pilot flying. In addition, more experienced pilots were more likely to have wrong reactions to warnings while acting as the monitoring pilot. These results suggest that both expertise and flight responsibility influence pilots' reactions to alerts. Considering crew pairing strategy, when a pilot flying is a less experienced pilot, a more experience pilot is suggested to be the monitoring pilot. The results of this study have implications for understanding pilots' behaviors to flight deck alerts, calling for specialized training and design of approach alarms on the flight deck.

Space Shuttle Projects

NASA Image and Video Library

1991-08-01

The free-flying Tracking and Data Relay Satellite-E (TDRS-E), still attached to an Inertial Upper Stage (IUS), was photographed by one of the crewmembers during the STS-43 mission. The TDRS-E was boosted by the IUS into geosynchronous orbit and positioned to remain stationary 22,400 miles above the Pacific Ocean southwest of Hawaii. The TDRS system provides almost uninterrupted communications with Earth-orbiting Shuttles and satellites, and had replaced the intermittent coverage provided by globe-encircling ground tracking stations used during the early space program. The TDRS can transmit and receive data, and track a user spacecraft in a low Earth orbit. The IUS is an unmarned transportation system designed to ferry payloads from low Earth orbit to higher orbits that are unattainable by the Shuttle. The Space Shuttle Orbiter Atlantis for the STS-43 mission was launched on August 2, 1991.

Note: Control of liquid helium supply to cryopanels of Kolkata superconducting cyclotron

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhattacharyya, T. K., E-mail: tamal@vecc.gov.in; Pal, G.

2015-02-15

The Kolkata superconducting cyclotron utilises liquid helium to cool the main magnet niobium-titanium (NbTi) coil and the cryopanels. Three liquid helium cooled cryopanels, placed inside the dees of the radio-frequency system, maintain the high vacuum in the acceleration region of the superconducting cyclotron. The small cryostat placed inside the cryogenic distribution manifold located at the basement of the superconducting cyclotron building supplies liquid helium in parallel branches to three cold heads, used for cooling their associated cryopanels. The level in the cryostat has to be maintained at an optimum value to ensure uninterrupted flow of liquid helium to these threemore » cold heads. This paper describes the transfer function of the overall system, its tuning parameters, and discusses the actual control of cryostat level by using these parameters.« less

In Search of the Nature of Extensive Reading in L2: Cognitive, Affective, and Pedagogical Perspectives

ERIC Educational Resources Information Center

Yamashita, Junko

2015-01-01

Extensive reading (ER) has been implemented under a wide variety of names, such as "(uninterrupted) sustained silent reading," "free voluntary reading," "pleasure reading," "book flood," "independent reading," and "Drop Everything And Read (DEAR)"; its various names emphasize different…

32 CFR 552.84 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 3 2010-07-01 2010-07-01 true Purpose. 552.84 Section 552.84 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY MILITARY RESERVATIONS AND NATIONAL CEMETERIES... training areas. Uninterrupted military use is vital to maintain and improve the combat readiness of the US...

RIF + USSR = R.E.A.D.

ERIC Educational Resources Information Center

Ball, Diane A.

A junior high school reading program entitled Reading for Enjoyment and Development (READ) that combines the Reading is Fundamental (RIF) inexpensive book distribution program and the practice of entire school participation in uninterrupted sustained silent reading (USSR) is described in this paper. The development of the project and practical…

Plastic covering on airfoil structure provides smooth uninterrupted surface

NASA Technical Reports Server (NTRS)

Kinzler, J. A.; Fehrenkamp, L. G.; Heffernam, J. T.; Lee, W. S.

1975-01-01

Primed surface is covered with adhesive. Sheet of plastic film is stretched over adhesive and mechanical holder is used to apply tension to ends of sheet to make it conform to surface of airfoil. After adhesive cures, plastic can be trimmed with sharp cutting tool.

Uninterrupted Scholars Act

THOMAS, 112th Congress

Sen. Landrieu, Mary L. [D-LA

2012-08-01

Senate - 08/01/2012 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Notes: For further action, see S.3472, which became Public Law 112-278 on 1/14/2013. Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

32 CFR 260.3 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... operations. Direct competition. The presence and operation of a DoD Component vending machine or a vending... machines or vending facilities operated in areas serving employees, the majority of whom normally do not have access (in terms of uninterrupted ease of approach and the amount of time required to patronize...

32 CFR 260.3 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... operations. Direct competition. The presence and operation of a DoD Component vending machine or a vending... machines or vending facilities operated in areas serving employees, the majority of whom normally do not have access (in terms of uninterrupted ease of approach and the amount of time required to patronize...

32 CFR 260.3 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... operations. Direct competition. The presence and operation of a DoD Component vending machine or a vending... machines or vending facilities operated in areas serving employees, the majority of whom normally do not have access (in terms of uninterrupted ease of approach and the amount of time required to patronize...

Functional Analysis and Treatment of Noncompliance by Preschool Children

ERIC Educational Resources Information Center

Wilder, David A.; Harris, Carelle; Reagan, Renee; Rasey, Amy

2007-01-01

A functional analysis showed that noncompliance occurred most often for 2 preschoolers when it resulted in termination of a preferred activity, suggesting that noncompliance was maintained by positive reinforcement. A differential reinforcement procedure, which involved contingent access to coupons that could be exchanged for uninterrupted access…

All Children Deserve Uninterrupted Learning!

ERIC Educational Resources Information Center

Brown, Fred

2015-01-01

Teachers often start a new school year working extremely hard to reteach last year's content, particularly for their lower income students. According to "Making Summer Count," a report commissioned by The Wallace Foundation and written by researchers at Rand, rigorous studies of voluntary summer programs, mandatory summer programs, and…

On-Orbit Propulsion System Performance of ISS Visiting Vehicles

NASA Technical Reports Server (NTRS)

Martin, Mary Regina M.; Swanson, Robert A.; Kamath, Ulhas P.; Hernandez, Francisco J.; Spencer, Victor

2013-01-01

The International Space Station (ISS) represents the culmination of over two decades of unprecedented global human endeavors to conceive, design, build and operate a research laboratory in space. Uninterrupted human presence in space since the inception of the ISS has been made possible by an international fleet of space vehicles facilitating crew rotation, delivery of science experiments and replenishment of propellants and supplies. On-orbit propulsion systems on both ISS and Visiting Vehicles are essential to the continuous operation of the ISS. This paper compares the ISS visiting vehicle propulsion systems by providing an overview of key design drivers, operational considerations and performance characteristics. Despite their differences in design, functionality, and purpose, all visiting vehicles must adhere to a common set of interface requirements along with safety and operational requirements. This paper addresses a wide variety of methods for satisfying these requirements and mitigating credible hazards anticipated during the on-orbit life of propulsion systems, as well as the seamless integration necessary for the continued operation of the ISS.

RECOVERY ACT: DYNAMIC ENERGY CONSUMPTION MANAGEMENT OF ROUTING TELECOM AND DATA CENTERS THROUGH REAL-TIME OPTIMAL CONTROL (RTOC): Final Scientific/Technical Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ron Moon

This final scientific report documents the Industrial Technology Program (ITP) Stage 2 Concept Development effort on Data Center Energy Reduction and Management Through Real-Time Optimal Control (RTOC). Society is becoming increasingly dependent on information technology systems, driving exponential growth in demand for data center processing and an insatiable appetite for energy. David Raths noted, 'A 50,000-square-foot data center uses approximately 4 megawatts of power, or the equivalent of 57 barrels of oil a day1.' The problem has become so severe that in some cases, users are giving up raw performance for a better balance between performance and energy efficiency. Historically,more » power systems for data centers were crudely sized to meet maximum demand. Since many servers operate at 60%-90% of maximum power while only utilizing an average of 5% to 15% of their capability, there are huge inefficiencies in the consumption and delivery of power in these data centers. The goal of the 'Recovery Act: Decreasing Data Center Energy Use through Network and Infrastructure Control' is to develop a state of the art approach for autonomously and intelligently reducing and managing data center power through real-time optimal control. Advances in microelectronics and software are enabling the opportunity to realize significant data center power savings through the implementation of autonomous power management control algorithms. The first step to realizing these savings was addressed in this study through the successful creation of a flexible and scalable mathematical model (equation) for data center behavior and the formulation of an acceptable low technical risk market introduction strategy leveraging commercial hardware and software familiar to the data center market. Follow-on Stage 3 Concept Development efforts include predictive modeling and simulation of algorithm performance, prototype demonstrations with representative data center equipment to verify requisite performance and continued commercial partnering agreement formation to ensure uninterrupted development, and deployment of the real-time optimal control algorithm. As a software implementable technique for reducing power consumption, the RTOC has two very desirable traits supporting rapid prototyping and ultimately widespread dissemination. First, very little capital is required for implementation. No major infrastructure modifications are required and there is no need to purchase expensive capital equipment. Second, the RTOC can be rolled out incrementally. Therefore, the effectiveness can be proven without a large scale initial roll out. Through the use of the Impact Projections Model provided by the DOE, monetary savings in excess of $100M in 2020 and billions by 2040 are predicted. In terms of energy savings, the model predicts a primary energy displacement of 260 trillion BTUs (33 trillion kWh), or a 50% reduction in server power consumption. The model also predicts a corresponding reduction of pollutants such as SO2 and NOx in excess of 100,000 metric tonnes assuming the RTOC is fully deployed. While additional development and prototyping is required to validate these predictions, the relative low cost and ease of implementation compared to large capital projects makes it an ideal candidate for further investigation.« less

Operations and maintenance philosophy

DOE Office of Scientific and Technical Information (OSTI.GOV)

DUNCAN, G.P.

1999-10-28

This Operations and Maintenance (O&M) Philosophy document is intended to establish a future O&M vision, with an increased focus on minimizing worker exposure, ensuring uninterrupted retrieval operations, and minimizing operation life-cycle cost. It is intended that this document would incorporate O&M lessons learned into on-going and future project upgrades.

Teaching Social Work Students against the Grain: Negotiating the Constraints and Possibilities

ERIC Educational Resources Information Center

Daddow, Angela A.; Schneider, Britta

2017-01-01

Students who have followed routes to Western universities other than the 'traditional' one--that is, an uninterrupted path from school to university--face greater challenges to their democratic participation in higher education than their "traditional" counterparts. Until recently, universities have predominantly expected students with…

47 CFR 74.682 - Station identification.

Code of Federal Regulations, 2013 CFR

2013-10-01

... period of operation. (d) A period of operation is defined as a single uninterrupted transmission or a... Stations § 74.682 Station identification. (a) Each television broadcast auxiliary station operating with a..., at a natural break in program offerings by one of the following means: (1) Transmission of its own...

47 CFR 74.682 - Station identification.

Code of Federal Regulations, 2012 CFR

2012-10-01

... period of operation. (d) A period of operation is defined as a single uninterrupted transmission or a... Stations § 74.682 Station identification. (a) Each television broadcast auxiliary station operating with a..., at a natural break in program offerings by one of the following means: (1) Transmission of its own...

47 CFR 74.682 - Station identification.

Code of Federal Regulations, 2014 CFR

2014-10-01

... period of operation. (d) A period of operation is defined as a single uninterrupted transmission or a... Stations § 74.682 Station identification. (a) Each television broadcast auxiliary station operating with a..., at a natural break in program offerings by one of the following means: (1) Transmission of its own...

47 CFR 74.682 - Station identification.

Code of Federal Regulations, 2011 CFR

2011-10-01

... period of operation. (d) A period of operation is defined as a single uninterrupted transmission or a... Stations § 74.682 Station identification. (a) Each television broadcast auxiliary station operating with a..., at a natural break in program offerings by one of the following means: (1) Transmission of its own...

Long-Term Repetition Priming of Briefly Identified Objects

ERIC Educational Resources Information Center

Breuer, Andreas T.; Masson, Michael E. J.; Cohen, Anna-Lisa; Lindsay, D. Stephen

2009-01-01

The authors provide evidence that long-term memory encoding can occur for briefly viewed objects in a rapid serial visual presentation list, contrary to claims that the brief presentation and quick succession of objects prevent encoding by disrupting a memory consolidation process that requires hundreds of milliseconds of uninterrupted processing.…

14 CFR 153.5 - Aviation safety inspector airport access.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Aviation safety inspector airport access... TRANSPORTATION (CONTINUED) AIRPORTS AIRPORT OPERATIONS Aviation Safety Inspector Access § 153.5 Aviation safety... must grant Aviation Safety Inspectors bearing FAA Form 110A free and uninterrupted access to public-use...

Time Out for Time Management.

ERIC Educational Resources Information Center

Herr, Judy; And Others

1995-01-01

Discusses time management skills, noting that effective time management entails awareness of such things as how we use time and when our mental energy peaks and falls. Offers time management suggestions for day-care administrators such as developing a realistic "to-do" list, scheduling uninterrupted time to engage in important tasks, and limiting…

Teacher Modeling: Its Impact on an Extensive Reading Program

ERIC Educational Resources Information Center

Loh, Jason Kok Khiang

2009-01-01

This case study investigates whether teachers model reading in 1 Singapore primary school during an exercise called "uninterrupted sustained silent reading" (USSR) carried out in the classroom. Even though reading is an important determinant of a student's growth in language skills and ability, and modeling the act of reading is…

32 CFR 809a.2 - Military responsibility and authority.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false Military responsibility and authority. 809a.2 Section 809a.2 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE... installations, to ensure the uninterrupted and successful accomplishment of the Air Force mission. (b) Each...

32 CFR 809a.2 - Military responsibility and authority.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 6 2011-07-01 2011-07-01 false Military responsibility and authority. 809a.2 Section 809a.2 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE... installations, to ensure the uninterrupted and successful accomplishment of the Air Force mission. (b) Each...

32 CFR 809a.2 - Military responsibility and authority.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Military responsibility and authority. 809a.2 Section 809a.2 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE... installations, to ensure the uninterrupted and successful accomplishment of the Air Force mission. (b) Each...

32 CFR 809a.2 - Military responsibility and authority.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false Military responsibility and authority. 809a.2 Section 809a.2 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE... installations, to ensure the uninterrupted and successful accomplishment of the Air Force mission. (b) Each...

32 CFR 809a.2 - Military responsibility and authority.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false Military responsibility and authority. 809a.2 Section 809a.2 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE... installations, to ensure the uninterrupted and successful accomplishment of the Air Force mission. (b) Each...

View looking west from the Justice Department Building to the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View looking west from the Justice Department Building to the Departmental Auditorium; note the uninterrupted cornice line along Constitution Avenue (this view is similar to HABS No. DC-809-1 (ct)) - United States Department of Justice, Constitution Avenue between Ninth & Tenth Streets, Northwest, Washington, District of Columbia, DC

77 FR 58491 - Drawbridge Operation Regulation; Willamette River, Portland, OR

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-21

... deviation is necessary to accommodate the running of the Portland Marathon. This deviation allows the bridge to remain in the down or closed position during the marathon. DATES: This deviation is effective from... vessel traffic to facilitate safe, uninterrupted roadway passage of participants of the Portland Marathon...

a Continual Engagement Approach Through Gis-Mcda Conflict Resolution of Loggerhead Sea Turtle Bycatch in Mexico

NASA Astrophysics Data System (ADS)

Bojórquez-Tapia, L. A.

2015-12-01

Continual engagement is an approach that emphasizes of uninterrupted interaction with the stakeholders with the purpose of fully integrating their knowledge into policymaking process. It focuses on the creation of hybrid scientific-local knowledge highly relevant to community and policy makers needs, while balancing the power asymmetries among stakeholders. Hence, it presupposes a capacity for a continuous revision and adjustment of the analyses that support the policymaking process. While continual engagement implies a capacity for enabling an effective communication, translation and mediation of knowledge among the diverse stakeholders, experts and policymakers, it also means keeping a close eye out for how knowledge evolves and how new data and information is introduced along a policymaking process. Through a case study, the loggerhead sea turtle (Caretta caretta) fishing bycatch in Mexico, a geographical information system-multicriteria modeling (GIS-MCDA) approach is presented to address the challenges of implementing continual engagement in conflict resolution processes. The GIS-MCDA combined the analytical hierarchy process (AHP) and compromise programming (CP) to generate consensus regarding the spatial pattern of conflicts. The AHP was fundamental for synthesizing the different sources of knowledge into a geospatial model. In particular, the AHP enabled the assess the salience, legitimacy, and credibility of the information produced for all involved. Results enabled the development of specific policies based upon an assessment of the risk of the loggerhead population to different levels of fishing bycatch, and the needs of the fishing communities in the region.

Chiropractic: origins, controversies, and contributions.

PubMed

Kaptchuk, T J; Eisenberg, D M

1998-11-09

Chiropractic is an important component of the US health care system and the largest alternative medical profession. In this overview of chiropractic, we examine its history, theory, and development; its scientific evidence; and its approach to the art of medicine. Chiropractic's position in society is contradictory, and we reveal a complex dynamic of conflict and diversity. Internally, chiropractic has a dramatic legacy of strife and factionalism. Externally, it has defended itself from vigorous opposition by conventional medicine. Despite such tensions, chiropractors have maintained a unified profession with an uninterrupted commitment to clinical care. While the core chiropractic belief that the correction of spinal abnormality is a critical health care intervention is open to debate, chiropractic's most important contribution may have to do with the patient-physician relationship.

INJECTION SYSTEM DESIGN FOR THE BSNS/RCS.

DOE Office of Scientific and Technical Information (OSTI.GOV)

WEI, J.; TANG, J.Y.; CHEN, Y.

2006-06-23

The BSNS injection system is designed to take one uninterrupted long drift in one of the four dispersion-free straight sections to host all the injection devices. Painting bumper magnets are used for both horizontal and vertical phase space painting. Closed-orbit bumper magnets are used for facilitating the installation of the injection septa and decreasing proton traversal in the stripping foil. Even with large beam emittance of about 300 {pi}mm.mrad used, BSNS/RCS still approaches the space charge limit during the injection/trapping phase for the accumulated particles of 1.9*10{sup 13} and at the low injection energy of 80 MeV. Uniform-like beam distributionmore » by well-designed painting scheme is then obtained to decrease the tune shift/spread. ORBIT code is used for the 3D simulations. Upgrading to higher injection energy has also been considered.« less

Space Shuttle Projects

NASA Image and Video Library

1991-08-01

The primary payload of the STS-43 mission, Tracking and Data Relay Satellite-E (TDRS-E) attached to an Inertial Upper Stage (IUS) was photographed at the moment of its release from the cargo bay of the Space Shuttle Orbiter Atlantis. The TDRS-E was boosted by the IUS into geosynchronous orbit and positioned to remain stationary 22,400 miles above the Pacific Ocean southwest of Hawaii. The TDRS system provides almost uninterrupted communications with Earth-orbiting Shuttles and satellites, and had replaced the intermittent coverage provided by globe-encircling ground tracking stations used during the early space program. The TDRS can transmit and receive data, and track a user spacecraft in a low Earth orbit. The IUS is an unmarned transportation system designed to ferry payloads from low Earth orbit to higher orbits that are unattainable by the Shuttle. The launch of STS-43 occurred on August 2, 1991.

Scalable synthesis of sequence-defined, unimolecular macromolecules by Flow-IEG

PubMed Central

Leibfarth, Frank A.; Johnson, Jeremiah A.; Jamison, Timothy F.

2015-01-01

We report a semiautomated synthesis of sequence and architecturally defined, unimolecular macromolecules through a marriage of multistep flow synthesis and iterative exponential growth (Flow-IEG). The Flow-IEG system performs three reactions and an in-line purification in a total residence time of under 10 min, effectively doubling the molecular weight of an oligomeric species in an uninterrupted reaction sequence. Further iterations using the Flow-IEG system enable an exponential increase in molecular weight. Incorporating a variety of monomer structures and branching units provides control over polymer sequence and architecture. The synthesis of a uniform macromolecule with a molecular weight of 4,023 g/mol is demonstrated. The user-friendly nature, scalability, and modularity of Flow-IEG provide a general strategy for the automated synthesis of sequence-defined, unimolecular macromolecules. Flow-IEG is thus an enabling tool for theory validation, structure–property studies, and advanced applications in biotechnology and materials science. PMID:26269573

Passive morphing of flying wing aircraft: Z-shaped configuration

NASA Astrophysics Data System (ADS)

Mardanpour, Pezhman; Hodges, Dewey H.

2014-01-01

High Altitude, Long Endurance (HALE) aircraft can achieve sustained, uninterrupted flight time if they use solar power. Wing morphing of solar powered HALE aircraft can significantly increase solar energy absorbency. An example of the kind of morphing considered in this paper requires the wings to fold so as to orient a solar panel to be hit more directly by the sun's rays at specific times of the day. An example of the kind of morphing considered in this paper requires the wings to fold so as to orient a solar panel that increases the absorption of solar energy by decreasing the angle of incidence of the solar radiation at specific times of the day. In this paper solar powered HALE flying wing aircraft are modeled with three beams with lockable hinge connections. Such aircraft are shown to be capable of morphing passively, following the sun by means of aerodynamic forces and engine thrusts. The analysis underlying NATASHA (Nonlinear Aeroelastic Trim And Stability of HALE Aircraft), a computer program that is based on geometrically exact, fully intrinsic beam equations and a finite-state induced flow model, was extended to include the ability to simulate morphing of the aircraft into a "Z" configuration. Because of the "long endurance" feature of HALE aircraft, such morphing needs to be done without relying on actuators and at as near zero energy cost as possible. The emphasis of this study is to substantially demonstrate the processes required to passively morph a flying wing into a Z-shaped configuration and back again.

Differential changes in myoelectric characteristics of slow and fast fatigable frog muscle fibres during long-lasting activity.

PubMed

Vydevska-Chichova, M; Mileva, K; Radicheva, N

2007-04-01

The electrical activity of different muscle fibre types during fatigue at varying stimulation frequency and fibre stretch was studied. Extracellular action potentials (ECAPs) were recorded from isolated frog muscle fibres at initial length and stretched by 15%, 25% and 35% and stimulated for 180 s by suprathreshold pulses with frequencies of 5, 6.7 and 10Hz. The changes in ECAP negative phase duration (T(0)), propagation velocity of excitation (PV), potential power spectrum and its median frequency (MDF) were analysed for the period of uninterrupted activity (endurance time, ET). Slow (SMF) and fast (FMF) fatigable muscle fibre types were distinguished by the rate of PV decrease during ET. With the increase of stimulation frequency and fibre stretch, the rate of ECAP parameter changes increased and was larger in FMF, but this proportion was reversed with stretching over 25% and 10Hz stimulation. In both fibre types the power spectrum shift to lower frequencies during continuous activity was more pronounced with higher stimulation frequency. In FMFs the rates of MDF changes were positively and more strongly correlated with the rates of PV changes, whilst in SMFs the inverse correlation between the rates of changes of MDF and T(0) was stronger. The results indicate specific adaptation of slow and fast fatigable muscle fibres to stretch and activation frequency due to the differences in their membrane processes.

Continuous flow real-time PCR device using multi-channel fluorescence excitation and detection.

PubMed

Hatch, Andrew C; Ray, Tathagata; Lintecum, Kelly; Youngbull, Cody

2014-02-07

High throughput automation is greatly enhanced using techniques that employ conveyor belt strategies with un-interrupted streams of flow. We have developed a 'conveyor belt' analog for high throughput real-time quantitative Polymerase Chain Reaction (qPCR) using droplet emulsion technology. We developed a low power, portable device that employs LED and fiber optic fluorescence excitation in conjunction with a continuous flow thermal cycler to achieve multi-channel fluorescence detection for real-time fluorescence measurements. Continuously streaming fluid plugs or droplets pass through tubing wrapped around a two-temperature zone thermal block with each wrap of tubing fluorescently coupled to a 64-channel multi-anode PMT. This work demonstrates real-time qPCR of 0.1-10 μL droplets or fluid plugs over a range of 7 orders of magnitude concentration from 1 × 10(1) to 1 × 10(7). The real-time qPCR analysis allows dynamic range quantification as high as 1 × 10(7) copies per 10 μL reaction, with PCR efficiencies within the range of 90-110% based on serial dilution assays and a limit of detection of 10 copies per rxn. The combined functionality of continuous flow, low power thermal cycling, high throughput sample processing, and real-time qPCR improves the rates at which biological or environmental samples can be continuously sampled and analyzed.

21 CFR 640.22 - Collection of source material.

Code of Federal Regulations, 2010 CFR

2010-04-01

...) BIOLOGICS ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Platelets § 640.22 Collection of source material. (a) Whole blood used as the source of Platelets shall be collected as prescribed in § 640.4. (b... uninterrupted venipuncture with minimal damage to, and minimal manipulation of, the donor's tissue. [40 FR 4304...

The Comparative Effect of Single and Multiple Gloss Conditions on EFL Learners' Vocabulary Retention and Production

ERIC Educational Resources Information Center

Khabiri, Mona; Akbarpour, Raheleh

2011-01-01

Vocabulary glosses are considered effective learning tools since they decrease incorrect meaning inferences from context while keeping reading uninterrupted. The purpose of the present study was to examine the impact of different gloss conditions on intermediate EFL learners' vocabulary retention and production. The participants were 101 EFL…

78 FR 16257 - Notice of Intent To Prepare the Commonwealth of the Northern Mariana Islands Joint Military...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-14

... uninterrupted schedule. These RTAs are needed to support ongoing operational requirements, changes to U.S. force.... MARFORPAC, as the Executive Agent, has invited the Federal Aviation Administration (FAA); International...., Dandan Elementary School Cafeteria, Dandan Road, Dandan, Saipan, CNMI 96960 Thursday, April 11, 2013, 4...

76 FR 53820 - Safety Zone; Missouri River From the Border Between Montana and North Dakota

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-30

..., DHS. ACTION: Temporary final rule; change of effective period. SUMMARY: The Coast Guard is extending... continued and uninterrupted protection of levees and personnel involved in ongoing high water response... personnel involved in ongoing high water response. Failing to extend the effective dates for this rule...

26 CFR 49.4262(a)-1 - Taxable transportation.

Code of Federal Regulations, 2010 CFR

2010-04-01

...) MISCELLANEOUS EXCISE TAXES FACILITIES AND SERVICES EXCISE TAXES Transportation of Persons § 49.4262(a)-1 Taxable... which begins after November 15, 1962, only if such portion is not part of “uninterrupted international... transportation which begins after November 15, 1962, the tax, if applicable, applies only to the amount paid for...

Meeting Policymakers' Education Responsibilities Requires Cross-State Data Collaboration, Sharing, and Comparability. Breaking down State Silos

ERIC Educational Resources Information Center

Data Quality Campaign, 2012

2012-01-01

States have responsibilities to ensure that transferring students receive uninterrupted education and services, produce indicators that provide a complete picture, and ensure that information is comparable across states. However, states' and districts' ability to meet these responsibilities requires data capacity that can be undermined due to…

Teaching Practice and Cultural Difference of an English as Foreign Language Classroom in Taiwan

ERIC Educational Resources Information Center

Liao, Hsien-Chung; Yang, Cheng-Cheng

2012-01-01

Uninterrupted interactions of merchants and travelers from different countries stress the significance of English. The purpose of the study was to investigate what cultures and teaching practices are different between native English-speaking teachers and Taiwanese senior high school students. Three native English-speaking teachers and six…

Vegetation mapping as a guide to better silviculture

Treesearch

Marinus. Westveld

1951-01-01

Difficult and challenging problems confront the forester today. Disastrous floods, critical water shortages, and the uninterrupted trend of forest depletion have focused attention on the important role forests play in the strength, economy, and prosperity of the Nation. Forests are increasingly prized for recreation, the protection they afford sources of water, and...

29 CFR 785.22 - Duty of 24 hours or more.

Code of Federal Regulations, 2011 CFR

2011-07-01

... can usually enjoy an uninterrupted night's sleep. If sleeping period is of more than 8 hours, only 8.... Pa. 1947).) (b) Interruptions of sleep. If the sleeping period is interrupted by a call to duty, the... cannot get a reasonable night's sleep, the entire period must be counted. For enforcement purposes, the...

29 CFR 785.22 - Duty of 24 hours or more.

Code of Federal Regulations, 2012 CFR

2012-07-01

... can usually enjoy an uninterrupted night's sleep. If sleeping period is of more than 8 hours, only 8.... Pa. 1947).) (b) Interruptions of sleep. If the sleeping period is interrupted by a call to duty, the... cannot get a reasonable night's sleep, the entire period must be counted. For enforcement purposes, the...

29 CFR 785.22 - Duty of 24 hours or more.

Code of Federal Regulations, 2014 CFR

2014-07-01

... can usually enjoy an uninterrupted night's sleep. If sleeping period is of more than 8 hours, only 8.... Pa. 1947).) (b) Interruptions of sleep. If the sleeping period is interrupted by a call to duty, the... cannot get a reasonable night's sleep, the entire period must be counted. For enforcement purposes, the...

29 CFR 785.22 - Duty of 24 hours or more.

Code of Federal Regulations, 2013 CFR

2013-07-01

... can usually enjoy an uninterrupted night's sleep. If sleeping period is of more than 8 hours, only 8.... Pa. 1947).) (b) Interruptions of sleep. If the sleeping period is interrupted by a call to duty, the... cannot get a reasonable night's sleep, the entire period must be counted. For enforcement purposes, the...

Sensitivity to Social Contingency and Positive Emotion in 2-Month-Olds

ERIC Educational Resources Information Center

Soussignan, Robert; Nadel, Jacqueline; Canet, Pierre; Gerardin, Priscille

2006-01-01

This study was aimed at sorting out conflicting results in the literature concerning 2-month-olds' sensitivity to interpersonal contingency, and investigated the potential role of infants' positive emotion in contingency detection. Infants were randomly assigned to an experimental group (EG) that was presented an uninterrupted live-replay-live…

Fernbank Forest Birds in the Summer.

ERIC Educational Resources Information Center

Schmalz, Georgann

1991-01-01

Provided is a listing of the common nesting birds and the neotropical migrant birds with nesting records in the approximate 65 acres of Fernbank Forest which is a preserve of mature urban hardwoods and pines within 10 miles of downtown Atlanta and a relic of what was once a large, uninterrupted tract of the Piedmont forest. (JJK)

21 CFR 1301.34 - Application for importation of Schedule I and II substances.

Code of Federal Regulations, 2010 CFR

2010-04-01

... light of changes in: (i) raw materials and other costs and (ii) conditions of supply and demand; (2) The... controlled substances to a number of establishments which can produce an adequate and uninterrupted supply of..., and industrial purposes; (2) Compliance with applicable State and local law; (3) Promotion of...

Endurance of Multiplication Fact Fluency for Students with Attention Deficit Hyperactivity Disorder

ERIC Educational Resources Information Center

Brady, Kelly K.; Kubina, Richard M., Jr.

2010-01-01

This study examines the relationship between a critical learning outcome of behavioral fluency and endurance, by comparing the effects of two practice procedures on multiplication facts two through nine. The first procedure, called whole time practice trial, consisted of an uninterrupted 1 minute practice time. The second procedure, endurance…

End results of radiation therapy, alone and combination with 5-fluorouracil in colorectal cancers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vongtama, V.; Douglass, H.O.; Moore, R.H.

The authors retrospectively analyzed the results of irradiation in 148 cases of primary inoperable and recurrent adenocarcinoma of the colon and rectum treated at the Department of Radiation Therapy, Roswell Park Memorial Institute between 1962 and 1970. This group includes 95 recurrences and 53 inoperable primaries. Uninterrupted radiotherapy was used in 118 cases and split-course technique in 30 cases. Eleven patients received combined radiotherapy and surgery. Seventy-eight patients received a combination of 5-fluorouracil (5-FU) and irradiation. The response rate and survival of individual groups is discussed in detail. This study indicated that perineal recurrences should receive whole pelvic irradiation inmore » addition to perineum field. Split-course technique appeared to yield a better survival than the uninterrupted course. The best 5-year survival rate (64 percent) is found in the group treated with a combination of radiation and surgery. For locally advanced, inoperable cancers, split-course technique, combined 5-FU and irradiation gave the best results, achieving longer palliation with improved quality of life and sometimes yielding cure (5-year survival). (auth)« less

A metallo-DNA nanowire with uninterrupted one-dimensional silver array

NASA Astrophysics Data System (ADS)

Kondo, Jiro; Tada, Yoshinari; Dairaku, Takenori; Hattori, Yoshikazu; Saneyoshi, Hisao; Ono, Akira; Tanaka, Yoshiyuki

2017-10-01

The double-helix structure of DNA, in which complementary strands reversibly hybridize to each other, not only explains how genetic information is stored and replicated, but also has proved very attractive for the development of nanomaterials. The discovery of metal-mediated base pairs has prompted the generation of short metal-DNA hybrid duplexes by a bottom-up approach. Here we describe a metallo-DNA nanowire—whose structure was solved by high-resolution X-ray crystallography—that consists of dodecamer duplexes held together by four different metal-mediated base pairs (the previously observed C-Ag-C, as well as G-Ag-G, G-Ag-C and T-Ag-T) and linked to each other through G overhangs involved in interduplex G-Ag-G. The resulting hybrid nanowires are 2 nm wide with a length of the order of micrometres to millimetres, and hold the silver ions in uninterrupted one-dimensional arrays along the DNA helical axis. The hybrid nanowires are further assembled into three-dimensional lattices by interactions between adenine residues, fully bulged out of the double helix.

Mental health promotion of Iranian university students: the effect of self-esteem and health locus of control.

PubMed

Moshki, M; Amiri, M; Khosravan, S

2012-10-01

The purpose of this study was to investigate the effect of self-esteem and health control belief on promoting students' mental health. In so doing, 144 students from two medical universities in the north-east of Iran were recruited into study. They were pair-matched and randomly assigned to case and control groups. The data were collected through Goldberg's General Health Questionnaire-28, Multidimensional Health Locus of Control and Rosenberg's Self-Esteem Scales. The results showed that there were significant differences between the groups before and after the intervention. The external components of health locus of control (chance and powerful others) showed a significant decrease but the internal health locus of control and self-esteem revealed a significant increase after the intervention (P < 0.0001). Moreover, the students' mental health had a significant increase after 3 months of intervention (P < 0.0001). The findings emphasize that the programme can improve the health locus of control beliefs, self-esteem and mental health promotion of the students. This will require additional monitoring and uninterrupted attempts to be effective. © 2011 Blackwell Publishing.

Real-time WAMI streaming target tracking in fog

NASA Astrophysics Data System (ADS)

Chen, Yu; Blasch, Erik; Chen, Ning; Deng, Anna; Ling, Haibin; Chen, Genshe

2016-05-01

Real-time information fusion based on WAMI (Wide-Area Motion Imagery), FMV (Full Motion Video), and Text data is highly desired for many mission critical emergency or security applications. Cloud Computing has been considered promising to achieve big data integration from multi-modal sources. In many mission critical tasks, however, powerful Cloud technology cannot satisfy the tight latency tolerance as the servers are allocated far from the sensing platform, actually there is no guaranteed connection in the emergency situations. Therefore, data processing, information fusion, and decision making are required to be executed on-site (i.e., near the data collection). Fog Computing, a recently proposed extension and complement for Cloud Computing, enables computing on-site without outsourcing jobs to a remote Cloud. In this work, we have investigated the feasibility of processing streaming WAMI in the Fog for real-time, online, uninterrupted target tracking. Using a single target tracking algorithm, we studied the performance of a Fog Computing prototype. The experimental results are very encouraging that validated the effectiveness of our Fog approach to achieve real-time frame rates.

Solvent signal suppression for high-resolution MAS-DNP

NASA Astrophysics Data System (ADS)

Lee, Daniel; Chaudhari, Sachin R.; De Paëpe, Gaël

2017-05-01

Dynamic nuclear polarization (DNP) has become a powerful tool to substantially increase the sensitivity of high-field magic angle spinning (MAS) solid-state NMR experiments. The addition of dissolved hyperpolarizing agents usually results in the presence of solvent signals that can overlap and obscure those of interest from the analyte. Here, two methods are proposed to suppress DNP solvent signals: a Forced Echo Dephasing experiment (FEDex) and TRAnsfer of Populations in DOuble Resonance Echo Dephasing (TRAPDORED) NMR. These methods reintroduce a heteronuclear dipolar interaction that is specific to the solvent, thereby forcing a dephasing of recoupled solvent spins and leaving acquired NMR spectra free of associated resonance overlap with the analyte. The potency of these methods is demonstrated on sample types common to MAS-DNP experiments, namely a frozen solution (of L-proline) and a powdered solid (progesterone), both containing deuterated glycerol as a DNP solvent. The proposed methods are efficient, simple to implement, compatible with other NMR experiments, and extendable past spectral editing for just DNP solvents. The sensitivity gains from MAS-DNP in conjunction with FEDex or TRAPDORED then permits rapid and uninterrupted sample analysis.

Efficacy of cocaine contingency management in heroin-assisted treatment: Results of a randomized controlled trial.

PubMed

Blanken, Peter; Hendriks, Vincent M; Huijsman, Ineke A; van Ree, Jan M; van den Brink, Wim

2016-07-01

To determine the efficacy of contingency management (CM), targeting cocaine use, as an add-on intervention for heroin dependent patients in supervised heroin-assisted treatment (HAT) with frequent cocaine use. Multi-center, open-label, parallel group, randomized controlled trial. Twelve specialized addiction treatment centers for HAT in The Netherlands; April 2006-January 2011. 214 chronic, treatment-refractory heroin dependent patients in HAT, with frequent cocaine use. Routine, daily supervised diacetylmorphine treatment, co-prescribed with oral methadone (HAT), with and without 6 months contingency management for cocaine use as an add-on intervention; HAT+CM and HAT-only, respectively. Primary outcome was the longest, uninterrupted duration of cocaine abstinence, based upon laboratory urinalysis. Secondary outcome measures included other cocaine-related measures, treatment retention in HAT, and multi-domain health-related treatment response. In an intention-to-treat analysis, HAT+CM was more effective than HAT-only in promoting longer, uninterrupted duration of cocaine abstinence (3.7 weeks versus 1.6 weeks; negative binomial regression: Exp(B)=2.34, 95%-CI: 1.70-3.23; p<0.001). This result remained significant in sensitivity analyses and was supported by all secondary, cocaine-related outcome measures. Treatment retention in HAT was high (91.6%) with no difference between the groups. The improvement in multi-domain health-related treatment response during the trial was numerically higher in HAT+CM (from 37.4% to 53.1%; +15.7%) than in HAT-only (from 44.5% to 46.5%; +2.0%), but this difference was statistically not significant. Contingency management is an effective add-on intervention to promote longer, uninterrupted periods of cocaine abstinence in chronic, treatment-refractory heroin dependent patients in heroin-assisted treatment with frequent cocaine use. The trial has been registered in The Netherlands National Trial Register under clinical trial registration number NTR4728. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Interrupted intracarotid artery cold saline infusion as an alternative method for neuroprotection after ischemic stroke.

PubMed

Ji, Ya-Bin; Wu, Yong-Ming; Ji, Zhong; Song, Wei; Xu, Sui-Yi; Wang, Yao; Pan, Su-Yue

2012-07-01

Intracarotid artery cold saline infusion (ICSI) is an effective method for protecting brain tissue, but its use is limited because of undesirable secondary effects, such as severe decreases in hematocrit levels, as well as its relatively brief duration. In this study, the authors describe and investigate the effects of a novel ICSI pattern (interrupted ICSI) relative to the traditional method (uninterrupted ICSI). Ischemic strokes were induced in 85 male Sprague-Dawley rats by occluding the middle cerebral artery for 3 hours using an intraluminal filament. Uninterrupted infusion groups received an infusion at 15 ml/hour for 30 minutes continuously. The same infusion speed was used in the interrupted infusion groups, but the whole duration was divided into trisections, and there was a 20-minute interval without infusion between sections. Forty-eight hours after reperfusion, H & E and silver nitrate staining were utilized for morphological assessment. Infarct sizes and brain water contents were determined using H & E staining and the dry-wet weight method, respectively. Levels of neuron-specific enolase (NSE), S100β protein, and matrix metalloproteinase 9 (MMP-9) in the serum were determined using enzyme-linked immunosorbent assay. Neurological deficits were also evaluated. Histology showed that interrupted ICSI did not affect neurons or fibers in rat brains, which suggests that this method is safe for brain tissues with ischemia. The duration of hypothermia induced by interrupted ICSI was longer than that induced via the traditional method, and the decrease in hematocrit levels was less pronounced. There were no differences in infarct size or brain water content between uninterrupted and interrupted ICSI groups, but neuron-specific enolase and matrix metalloproteinase 9 serum levels were more reduced after interrupted ICSI than after the traditional method. Interrupted ICSI is a safe method. Compared with traditional ICSI, the interrupted method has a longer duration of hypothermia and less effect on hematocrit and offers more potentially improved neuroprotection, thereby making it more attractive as an infusion technique in the clinic.

Comparison of intubation modalities in a simulated cardiac arrest with uninterrupted chest compressions.

PubMed

Tandon, Navin; McCarthy, Matthew; Forehand, Brett; Carlson, Jestin N

2014-10-01

Interruptions in chest compressions during cardiopulmonary resuscitation can negatively impact survival. Several new endotracheal intubation (ETI) techniques including video laryngoscopy may allow for ETI with minimal or no interruptions in chest compressions. We sought to determine the impact of three different ETI techniques upon time to intubation (TTI) in a simulated cardiac arrest during uninterrupted chest compression. We performed a randomised crossover study with a convenience sample of emergency physicians using three different ETI techniques: direct laryngoscopy (DL), GlideScope video laryngoscopy (GVL) and GlideScope video laryngoscopy with bougie (GVL-B). Providers performed ETI on a manikin on a hospital bed with concurrent chest compressions. Our primary outcome, TTI, was defined as the time from insertion of the laryngoscope blade until first breath. Given the correlated nature of the data, we used the paired t test to assess the differences in mean TTIs between GVL minus DL and GVL-B minus DL. We also ran the analysis stratified by provider experience. We enrolled 20 providers with a median TTI (IQR) by device of: DL 27 s (20.3, 35.4), GVL 20.6 s (17.7, 27.1) and GVL-B 60.1 s (39.1, 99). The mean GVL-DL difference was -10.1 s (-17.9-2.3) while the mean GVL-B-DL difference was 45.6 s (19.8-71.4) (p<0.001). The GVL-B required the greatest TTI across providers of varying experience levels. In this simulated model of cardiac arrest with uninterrupted chest compressions, TTI was shorter for GVL than DL while use of the GVL with bougie resulted in longer TTI. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Test-Enhanced E-Learning Strategies in Postgraduate Medical Education: A Randomized Cohort Study.

PubMed

DelSignore, Lisa A; Wolbrink, Traci A; Zurakowski, David; Burns, Jeffrey P

2016-11-21

The optimal design of pedagogical strategies for e-learning in graduate and postgraduate medical education remains to be determined. Video-based e-learning use is increasing, with initial research suggesting that taking short breaks while watching videos (independent of answering test questions) may improve learning by focusing attention on the content presented. Interspersed test questions may also improve knowledge acquisition and retention. To examine the effect of interspersed test questions and periodic breaks on immediate knowledge acquisition and retention at 6 months by pediatric residents engaged in video-based e-learning. First- and second-year pediatric residents were randomized to 1 of the following 3 groups: viewing the complete video uninterrupted (full video), viewing the video interrupted with unrelated logic puzzles (logic puzzles), or viewing the video interrupted with brief comprehension test questions (short answer questions). Residents answered pre- and post-tests before and after video viewing, followed by a retention test at 6 months. Primary outcome included comparison of the change in test scores between groups. A total of 49 residents completed the initial testing session. All 3 learning groups had comparable mean increases in immediate knowledge gain, but with no significant differences between groups (F 2,46 =0.35, P=.71). Thirty-five residents completed retention testing with comparable degrees of knowledge retention in the full video and short answer test questions groups (P<.001), but no significant change in the logic puzzles group (F 1,32 =2.44, P=.13). Improved knowledge gain was not demonstrated among residents answering interspersed questions or completing logic puzzles during interrupted online video viewing when compared with residents viewing uninterrupted video content. However, residents who either participated in uninterrupted video viewing or answered interspersed questions during interrupted video viewing demonstrated significant knowledge retention at 6 months. ©Lisa A DelSignore, Traci A Wolbrink, David Zurakowski, Jeffrey P Burns. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 21.11.2016.

Voices of the Oppressed and Oppressors First, History and Theory Last

ERIC Educational Resources Information Center

Ribkoff, Fred; Mirfakhraie, Amir

2015-01-01

The authors illustrate the process of a radical pedagogical paradigm shift from the teaching of oppression within historical and theoretical frameworks to a focus on the voices and experiences of the oppressed and oppressors uninterrupted by voices of the experts. This paradigmatic change evolved as a result of co-teaching a fourth-year global…

Intrapsychic dynamics, behavioral manifestations, and related interventions with youthful fire setters.

PubMed

Williams, Dian L; Clements, Paul T

2007-01-01

Fire setting in youth has often been overlooked and misunderstood as a coping skill for expressing rage. The act of deliberate fire setting, if uninterrupted, may continue throughout an individual's lifetime. Forensic examiners, mental health care providers, and criminal justice professionals can help guide referral and treatment through better understanding of behaviors and intrapsychic dynamics.

Adapting Reference for a Unique Group of Distance Learners: Serving the American Institute of Certified Public Accountants (AICPA)

ERIC Educational Resources Information Center

Martin, Maria Mathilde

2004-01-01

When a university acquires the library of a national institute and the institute's active and worldwide membership expects continued and uninterrupted access to services from the collection, shockwaves can reverberate throughout the university's main library and among its staff. This was especially true for the Reference Department of the…

When Your in Box Is Always Full: Scholars Struggle to Keep Technology from Controlling their Lives

ERIC Educational Resources Information Center

Fogg, Piper

2008-01-01

For many academics, managing the influx of daily communication has become a second job. While many scholars like the flexibility and creative opportunities technology affords, they have trouble turning off their gadgets. That can eat into time reserved for uninterrupted reading, writing, reflecting, or working in the laboratory. Technology has…

29 CFR 785.22 - Duty of 24 hours or more.

Code of Federal Regulations, 2010 CFR

2010-07-01

... can usually enjoy an uninterrupted night's sleep. If sleeping period is of more than 8 hours, only 8... v. Day & Zimmerman, 157 F. 2d 736 (C.A. 8, 1946); McLaughlin v. Todd & Brown, Inc., 7 W.H. Cases... cannot get a reasonable night's sleep, the entire period must be counted. For enforcement purposes, the...

Using a Critical Reflection Framework and Collaborative Inquiry to Improve Teaching Practice: An Action Research Project

ERIC Educational Resources Information Center

Briscoe, Patricia

2017-01-01

This action research reports on a three-year collaborative learning process among three teachers. We used current literature and a critical reflection framework to understand why our teaching approaches were not resulting in increased student learning. This allowed us to examine our previously unrecognized and uninterrupted--and often,…

7 CFR 52.47 - Changing types of service.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Certification Fees and Charges § 52.47 Changing types of service. If an applicant cancels a new year-round...-round rate and less than year-round rate for the full period the year-round contract was in effect. If an applicant cancels a year-round contract after a full year or more of uninterrupted service, the...

7 CFR 52.47 - Changing types of service.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Certification Fees and Charges § 52.47 Changing types of service. If an applicant cancels a new year-round...-round rate and less than year-round rate for the full period the year-round contract was in effect. If an applicant cancels a year-round contract after a full year or more of uninterrupted service, the...

Ancient India and the Body. Fulbright-Hays Summer Seminar Abroad 1994 (India).

ERIC Educational Resources Information Center

Wolak, William

This paper explores the representation of the human body through the literature and art of early India. From its beginning, Indian art has employed an uninterrupted iconic mode of representation that focuses on an anthropomorphic mimesis to describe desire, devotion, and ascetic denial. The paper focuses on the earliest such representations of the…

Best practices for continuous monitoring of temperature and flow in wadeable streams

Treesearch

Jen Stamp; Anna Hamilton; Michelle Craddock; Laila Parker; Allison H. Roy; Daniel J. Isaak; Zach Holden; Margaret Passmore; Britta G. Bierwagen

2014-01-01

The United States Environmental Protection Agency (U.S. EPA) is working with its regional offices, states, tribes, river basin commissions and other entities to establish Regional Monitoring Networks (RMNs) for freshwater wadeable streams. To the extent possible, uninterrupted, biological, temperature and hydrologic data will be collected on an ongoing basis at RMN...

Satellite Vulnerabilities

DTIC Science & Technology

2008-02-18

allies. 8  Satellites and Intelligence , Surveillance, and Reconnaissance We have become dependent also on our satellite surveillance assets...uninterrupted ISR”, with “space intelligence , surveillance, and reconnaissance (ISR) systems…fundamental to air power—especially to the execution...tremendous informational and intelligence advantage. But if we lose those satellites, or the links to them, we also lose the advantages of them, and

Development and evaluation of a prototype concentrating solar collector with thermocline based thermal energy storage for residential thermal usage

DOE PAGES

Kumar, Vinod; Afrin, Samia; Ortega, Jesus; ...

2013-09-01

A prototype of a concentrating solar collector (CSC) receiver was designed, built, and evaluated on-sun at the University of Texas at El Paso in El Paso, TX. This prototype receiver consists of two parabolic trough-reflectors but, in principle, the design can be efficiently extended to multiple units for achieving a higher temperature throughput. Each reflector has a vacuum tube collector at the focal point of the trough. The solar collector system was combined with a single-tank thermocline thermal energy storage (TES) for off-solar thermal usage. The main goal of this study is to develop an advanced solar hot water systemmore » for most residential applications. The focus of this study is to investigate the feasibility and performance of the solar thermal system by employing the recent advancement in the TES—a thermocline based TES—system for the concentrating solar power technologies developed by the Sandia National Laboratories and National Renewable Energy Laboratories for electricity production. A CSC when combined with TES has potential to provide uninterrupted thermal energy for most residential usages. This paper presents a detailed description of prototype design and materials required. The thermal energy storage tank utilizes an insulated 170 l (45 gal) galvanized steel tank. In order to maintain thermocline in the TES tank, with hot water on top and cold water at the bottom, two plate distributors are installed in the tank. The data showed a significant enhancement in thermal energy generation. This thermocline based single tank presented a thermal energy storage potential for at least three days (with diminishing storage capacity) that test were performed. The whole prototype was made for approximately USD 355 (excludes any labor costs) and hence also has strong potential for supplying clean thermal energy in most developing countries. As a result, tests of the prototype were conducted in November 2011.« less

Optimal control of M/M/1 two-phase queueing system with state-dependent arrival rate, server breakdowns, delayed repair, and N-policy

NASA Astrophysics Data System (ADS)

Rao, Hanumantha; Kumar, Vasanta; Srinivasa Rao, T.; Srinivasa Kumar, B.

2018-04-01

In this paper, we examine a two-stage queueing system where the arrivals are Poisson with rate depends on the condition of the server to be specific: vacation, pre-service, operational or breakdown state. The service station is liable to breakdowns and deferral in repair because of non-accessibility of the repair facility. The service is in two basic stages, the first being bulk service to every one of the customers holding up on the line and the second stage is individual to each of them. The server works under N-policy. The server needs preliminary time (startup time) to begin batch service after a vacation period. Startup times, uninterrupted service times, the length of each vacation period, delay times and service times follows an exponential distribution. The closed form of expressions for the mean system size at different conditions of the server is determined. Numerical investigations are directed to concentrate the impact of the system parameters on the ideal limit N and the minimum base expected unit cost.

Microelectromechanical safe arm device

DOEpatents

Roesler, Alexander W [Tijeras, NM

2012-06-05

Microelectromechanical (MEM) apparatus and methods for operating, for preventing unintentional detonation of energetic components comprising pyrotechnic and explosive materials, such as air bag deployment systems, munitions and pyrotechnics. The MEM apparatus comprises an interrupting member that can be moved to block (interrupt) or complete (uninterrupt) an explosive train that is part of an energetic component. One or more latching members are provided that engage and prevent the movement of the interrupting member, until the one or more latching members are disengaged from the interrupting member. The MEM apparatus can be utilized as a safe and arm device (SAD) and electronic safe and arm device (ESAD) in preventing unintentional detonations. Methods for operating the MEM apparatus include independently applying drive signals to the actuators coupled to the latching members, and an actuator coupled to the interrupting member.

Swot analysis of using aerostats for surveillance in counter terrorism

NASA Astrophysics Data System (ADS)

Çetin, Hüseyin

2013-06-01

In today's conjuncture, the terrorist activities are the most compelling issue for the defence forces in maintaining homeland security. Especially, the terrorist elements that penetrate the homeland may give harm. This harm can be minimized by preventing the terrorist penetrations from homeland borders. In counter terrorism, having Intelligence, Surveillance and Reconnaissance (ISR) capability and using this capability by twenty four hours is deterrence for the terrorist groups. Aerostats emerge as the ideal platform which can provide this capability. Aerostats are unmanned and aerodynamically shaped balloons that are stayed in the air, fixed to the ground by steel cable(s). The aerostat is made of a large fabric envelope that is filled with nonflammable helium gas, which provides the lifting force. The cables also serve to supply the electrical power to the aerostat systems, and for data relay between the aerostat and the ground station. Aerostats are different from the other manned and Unmanned Aerial Vehicles (UAVs) because of aerostats' capabilities such as cost effectiveness, long endurance and high resolution image transmission. Especially having uninterrupted image transmission and surveillance capabilities is important to be advantageous in counter terrorism. In this article, a short definition of terrorism has been given and then the importance of ensuring the homeland border security has been emphasized in counter terrorism. In addition, the questions of "what are the technical capabilities, the usage areas and the purposes of aerostats?" will be introduced as a result of literature review. Finally the strengths and weaknesses of aerostats, opportunities and threats for the near future will be introduced by using "SWOT" analysis method.

Canopy accession patterns of table mountain and pitch pines during the 19th and 20th centuries

Treesearch

Patrick H. Brose; Thomas A. Waldrop

2012-01-01

A dendrochronology study was conducted in three upland yellow pine stands in Georgia to determine whether the individual Table Mountain (Pinus pungens) and pitch (P. rigida) pines originated in sunny gaps or shaded understories, whether they grew uninterrupted into the canopy or were assisted by one or more releases, and whether...

The discovery of 9/8-ribbons, β/γ-peptides with curved shapes governed by a combined configuration-conformation code.

PubMed

Grison, Claire M; Robin, Sylvie; Aitken, David J

2015-11-21

The de novo design of a β/γ-peptidic foldamer motif has led to the discovery of an unprecedented 9/8-ribbon featuring an uninterrupted alternating C9/C8 hydrogen-bonding network. The ribbons adopt partially curved topologies determined synchronistically by the β-residue configuration and the γ-residue conformation sets.

Computing architecture for autonomous microgrids

DOEpatents

Goldsmith, Steven Y.

2015-09-29

A computing architecture that facilitates autonomously controlling operations of a microgrid is described herein. A microgrid network includes numerous computing devices that execute intelligent agents, each of which is assigned to a particular entity (load, source, storage device, or switch) in the microgrid. The intelligent agents can execute in accordance with predefined protocols to collectively perform computations that facilitate uninterrupted control of the .

Acute effects on cognitive performance following bouts of standing and light-intensity physical activity in a simulated workplace environment.

PubMed

Mullane, Sarah L; Buman, Matthew P; Zeigler, Zachary S; Crespo, Noe C; Gaesser, Glenn A

2017-05-01

To compare acute cognitive effects following bouts of standing (STAND), cycling (CYCLE) and walking (WALK) to a sit-only (SIT) condition. Randomized cross-over full-factorial study. Nine overweight (BMI=29±3kg/m 2 ) adults (30±15years; 7 females, 2 males) completed four conditions (SIT, STAND, WALK and CYCLE) across a 6h period with a 7days washout period between conditions. SIT consisted of uninterrupted sitting. Experimental conditions included intermittent bouts of standing (STAND), cycling (CYCLE) and walking (WALK). A cognitive performance battery (Cogstate) was completed twice in a seated position following bouts of standing and light-intensity physical activity. Mixed-effects models compared between-condition differences in standardized score (z-score), accuracy (%), and speed (log10ms). Cognitive performance z-score and accuracy measures were higher during STAND, CYCLE and WALK (P<0.05) conditions compared to the SIT condition. CYCLE was better than other experimental conditions. Compared to uninterrupted sitting, short bouts of standing or light-intensity cycling and walking may improve acute cognitive performance. Copyright © 2016 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

Three good reasons for heart surgeons to understand cardiac metabolism.

PubMed

Doenst, Torsten; Bugger, Heiko; Schwarzer, Michael; Faerber, Gloria; Borger, Michael A; Mohr, Friedrich W

2008-05-01

It is the principal goal of cardiac surgeons to improve or reinstate contractile function with, through or after a surgical procedure on the heart. Uninterrupted contractile function of the heart is irrevocably linked to the uninterrupted supply of energy in the form of ATP. Thus, it would appear natural that clinicians interested in myocardial contractile function are interested in the way the heart generates ATP, i.e. the processes generally referred to as energy metabolism. Yet, it may appear that the relevance of energy metabolism in cardiac surgery is limited to the area of cardioplegia, which is a declining research interest. It is the goal of this review to change this trend and to illustrate the role and the therapeutic potential of metabolism and metabolic interventions for management. We present three compelling reasons why cardiac metabolism is of direct, practical interest to the cardiac surgeon and why a better understanding of energy metabolism might indeed result in improved surgical outcomes: (1) To understand cardioplegic arrest, ischemia and reperfusion, one needs a working knowledge of metabolism; (2) hyperglycemia is an underestimated and modifiable risk factor; (3) acute metabolic interventions can be effective in patients undergoing cardiac surgery.

Three years of ULTRASPEC at the Thai 2.4-m telescope: Capabilities and scientific highlights

NASA Astrophysics Data System (ADS)

Yadav, Ram Kesh; Richichi, Andrea; Irawati, Puji; Dhillon, Vikram Singh; Marsh, Thomas R.; Soonthornthum, Boonrucksar

2018-04-01

High temporal resolution observations enable the study of rapid phenomena such as the flux variations in binary system objects, e.g. cataclysmic variables, compact binary systems, the flux variations in young star clusters, stellar occultations and more. The 2.4-m Thai National Telescope (TNT) is ideally suited for this niche research, being the largest facility in Southeast Asia and being equipped with ULTRASPEC, a high-speed imager based on a low-noise frame transfer electron-multiplying CCD. In the sub-window mode, ULTRASPEC can record uninterrupted sequences with frame rates as fast as few milliseconds. We present some of the key results obtained in the area of high time resolution with ULTRASPEC. We also present the results of a recent worldwide campaign to observe the current series of lunar occultations of Aldebaran (α Tauri) carried out in close collaboration with the Devasthal facilities, the out-of-eclipse variations on the post common-envelope system J1021+1744, and pre-main-sequence variables in young open cluster Stock 8.

Downtime procedures for the 21st century: using a fully integrated health record for uninterrupted electronic reporting of laboratory results during laboratory information system downtimes.

PubMed

Oral, Bulent; Cullen, Regina M; Diaz, Danny L; Hod, Eldad A; Kratz, Alexander

2015-01-01

Downtimes of the laboratory information system (LIS) or its interface to the electronic medical record (EMR) disrupt the reporting of laboratory results. Traditionally, laboratories have relied on paper-based or phone-based reporting methods during these events. We developed a novel downtime procedure that combines advance placement of orders by clinicians for planned downtimes, the printing of laboratory results from instruments, and scanning of the instrument printouts into our EMR. The new procedure allows the analysis of samples from planned phlebotomies with no delays, even during LIS downtimes. It also enables the electronic reporting of all clinically urgent results during downtimes, including intensive care and emergency department samples, thereby largely avoiding paper- and phone-based communication of laboratory results. With the capabilities of EMRs and LISs rapidly evolving, information technology (IT) teams, laboratories, and clinicians need to collaborate closely, review their systems' capabilities, and design innovative ways to apply all available IT functions to optimize patient care during downtimes. Copyright© by the American Society for Clinical Pathology.

A temperature reversal within the rapid Younger Dryas-Holocene warming in the North Atlantic?

NASA Astrophysics Data System (ADS)

Vincent, Jessie H.; Cwynar, Les C.

2016-12-01

The onset of the Holocene has been generally considered rapid and uninterrupted in the circum-Atlantic region. Loss-on-ignition (LOI - an index of organic carbon) profiles from 18 lateglacial-aged lakes in Nova Scotia, Canada, together with chironomid-inferred temperature reconstructions at 5 sites, demonstrate that the rapid warming from the Younger Dryas (GS-1) to the Holocene was interrupted by a cooling of 1.6-6.4 °C in summer surface lake water temperature. The resulting inflection or reversal on the rising temperature curve has also been identified at 35 sites outside Nova Scotia from terrestrial and marine settings, indicating that this cool step is a robust feature throughout the North Atlantic and is likely the result of major oceanic and atmospheric reorganization of the Holocene climate system.

The Orbital Design of Alpha Centauri Exoplanet Satellite (ACESat)

NASA Technical Reports Server (NTRS)

Weston, Sasha; Belikov, Rus; Bendek, Eduardo

2015-01-01

Exoplanet candidates discovered by Kepler are too distant for biomarkers to be detected with foreseeable technology. Alpha Centauri has high separation from other stars and is of close proximity to Earth, which makes the binary star system 'low hanging fruit' for scientists. Alpha Centauri Exoplanet Satellite (ACESat) is a mission proposed to Small Explorer Program (SMEX) that will use a coronagraph to search for an orbiting planet around one of the stars of Alpha Centauri. The trajectory design for this mission is presented here where three different trajectories are considered: Low Earth Orbit (LEO), Geosynchronous Orbit (GEO) and a Heliocentric Orbit. Uninterrupted stare time to Alpha Centauri is desirable for meeting science requirements, or an orbit that provides 90% stare time to the science target. The instrument thermal stability also has stringent requirements for proper function, influencing trajectory design.

Giant star seismology

NASA Astrophysics Data System (ADS)

Hekker, S.; Christensen-Dalsgaard, J.

2017-06-01

The internal properties of stars in the red-giant phase undergo significant changes on relatively short timescales. Long near-uninterrupted high-precision photometric timeseries observations from dedicated space missions such as CoRoT and Kepler have provided seismic inferences of the global and internal properties of a large number of evolved stars, including red giants. These inferences are confronted with predictions from theoretical models to improve our understanding of stellar structure and evolution. Our knowledge and understanding of red giants have indeed increased tremendously using these seismic inferences, and we anticipate that more information is still hidden in the data. Unraveling this will further improve our understanding of stellar evolution. This will also have significant impact on our knowledge of the Milky Way Galaxy as well as on exo-planet host stars. The latter is important for our understanding of the formation and structure of planetary systems.

The Draft as a Deterrent Influence on U.S. Military Interventions

DTIC Science & Technology

2008-06-13

American Involvement in the Vietnam War , “Protest on the Homefront ...Payne125 pages. With the growing unpopularity of the war in Iraq, Americans are once again discussing the draft. Congressman Charles Rangel has argued...three years uninterrupted. The drafts of the American Civil War and World War I are now the domain solely of history books.8 With the migration of the

Rx fire laws: tools to protect fire: the `ecological imperative?

Treesearch

Dale Wade; Steven Miller; Johnny Stowe; James Brenner

2006-01-01

The South is the birthplace of statutes and ordinances that both advocate and protect the cultural heritage of woods burning, which has been practiced in this region uninterrupted for more than 10,000 years. We present a brief overview of fire use in the South and discuss why most southern states recognized early on that periodic fire was necessary to sustain fire...

77 FR 12407 - Statement of Agency Policy and Interpretation on the Hours of Service Laws as Amended; Response...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-29

... 5. Commuting Time 6. Application of Exception to Limitation on Certain Limbo Time V. Portions of FRA... time plus limbo time exceeds 12 hours mandatory, or may the employee decline it? 3. If an employee is called to report for duty after having 10 hours of uninterrupted time off duty, but then receives a call...

EPHEDRA, THE OLDEST MEDICINAL PLANT WITH THE HISTORY OF AN UNINTERRUPTED USE

PubMed Central

Mahdihassan, S.

1987-01-01

Ephedra was a source of anti-fatigue drink. In later period it became a drink of immortality and longevity. The use of Soma as the first drink of a newly born child is mentioned in Rigveda. The author identifies the Soma of Rigveda with the Ephedra and established its use in ancient Rome and also highlights here its continuity among Zorostrains. PMID:22557597

U.S. Energy Security -- The Campaign We Must Win

DTIC Science & Technology

2009-03-23

population.2 Our industry, commerce, transportation and economic livelihood require the uninterrupted supply of energy. In all its forms, energy underpins...mitigate our vulnerability to unstable oil prices. Rising global demand and competition threatens our ability to secure long term economical access... economically while strengthening our enemies. This research paper addresses the effectiveness of U.S. energy policy and proposes a new approach that seeks to

JPRS Report, Soviet Union, Political Affairs, Republic Language Legislation.

DTIC Science & Technology

1989-12-05

reference materials ( dictionaries , termi- nology glossaries, phrase books, self-taught books, and so on), and qualified specialists in the field of...textbooks; d) to publish self-taught manuals, phrase books, and explanatory and bilingual dictionaries for the aid of persons desiring to study...Armenian. To create the nec- essary printing facility base to publish high-quality illus- trated dictionaries ; to provide uninterrupted delivery of

Operational present status and reliability analysis of the upgraded EAST cryogenic system

NASA Astrophysics Data System (ADS)

Zhou, Z. W.; Y Zhang, Q.; Lu, X. F.; Hu, L. B.; Zhu, P.

2017-12-01

Since the first commissioning in 2005, the cryogenic system for EAST (Experimental Advanced Superconducting Tokamak) has been cooled down and warmed up for thirteen experimental campaigns. In order to promote the refrigeration efficiencies and reliability, the EAST cryogenic system was upgraded gradually with new helium screw compressors and new dynamic gas bearing helium turbine expanders with eddy current brake to improve the original poor mechanical and operational performance from 2012 to 2015. Then the totally upgraded cryogenic system was put into operation in the eleventh cool-down experiment, and has been operated for the latest several experimental campaigns. The upgraded system has successfully coped with various normal operational modes during cool-down and 4.5 K steady-state operation under pulsed heat load from the tokamak as well as the abnormal fault modes including turbines protection stop. In this paper, the upgraded EAST cryogenic system including its functional analysis and new cryogenic control networks will be presented in detail. Also, its operational present status in the latest cool-down experiments will be presented and the system reliability will be analyzed, which shows a high reliability and low fault rate after upgrade. In the end, some future necessary work to meet the higher reliability requirement for future uninterrupted long-term experimental operation will also be proposed.

Apple dwarfing rootstocks and interstocks affect the type of growth units produced during the annual growth cycle: precocious transition to flowering affects the composition and vigour of annual shoots.

PubMed

Seleznyova, Alla N; Tustin, D Stuart; Thorp, T Grant

2008-04-01

Precocious flowering in apple trees is often associated with a smaller tree size. The hypothesis was tested that floral evocation in axillary buds, induced by dwarfing rootstocks, reduces the vigour of annual shoots developing from these buds compared with shoots developing from vegetative buds. The experimental system provided a wide range of possible tree vigour using 'Royal Gala' scions and M.9 (dwarfing) and MM.106 (non-dwarfing) as rootstocks and interstocks. Second-year annual shoots were divided into growth units corresponding to periods (flushes) of growth namely, vegetative spur, extension growth unit, uninterrupted growth unit, floral growth unit (bourse) and extended bourse. The differences between the floral and vegetative shoots were quantified by the constituent growth units produced. The dwarfing influence was expressed, firstly, in reduced proportions of shoots that contained at least one extension growth unit and secondly, in reduced proportions of bicyclic shoots (containing two extension growth units) and shoots with an uninterrupted growth unit. In treatments where floral shoots were present, they were markedly less vigorous than vegetative shoots with respect to both measures. In treatments with M.9 rootstock, vegetative and floral shoots produced on average 0.52 and 0.17 extension growth units, compared with 0.77 extension growth units per shoot in the MM.106 rootstock treatment. Remarkably, the number of nodes per extension growth unit was not affected by the rootstock/interstock treatments. These results showed that rootstocks/interstocks affect the type of growth units produced during the annual growth cycle, reducing the number of extension growth units, thus affecting the composition and vigour of annual shoots. This effect is particularly amplified by the transition to flowering induced by dwarfing rootstocks. The division of annual shoot into growth units will also be useful for measuring and modelling effects of age on apple tree architecture.

Population Parameters of Blainvilles and Cuviers Beaked Whales

DTIC Science & Technology

2015-09-30

cetacean populations. Long-term monitoring of beaked whale populations in El Hierro , a nearly pristine habitat far from areas of sonar testing or...marine industry, enables valuable studies of demographic trends and life history dictated mainly by natural parameters. El Hierro is in process of...functioning (expected in 2018-2019), it is essential to continue monitoring the populations in El Hierro to obtain an uninterrupted long-term dataset of

Book: Marine Bioacoustic Signal Processing and Analysis

DTIC Science & Technology

2011-09-30

physicists , and mathematicians . However, more and more biologists and psychologists are starting to use advanced signal processing techniques and...Book: Marine Bioacoustic Signal Processing and Analysis 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT ...chapters than it should be, since the project must be finished by Dec. 31. I have started setting aside 2 hours of uninterrupted per workday to work

The Science, Engineering and Technology Career Library Corner. Final report, February 1, 1995--January 31, 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cole, P.R.

1996-03-01

A grant was made to install and pilot-test the Science, Engineering and Technology (SET) Career Library Corner at the New York Hall of Science. The SET Career Library Corner is located in a multi-media library setting where visitors can explore careers in a quiet, uninterrupted environment, in contrast to the original installation designed as a museum floor exhibit.

Improved assay to detect Plasmodium falciparum using an uninterrupted, semi-nested PCR and quantitative lateral flow analysis

PubMed Central

2013-01-01

Background A rapid, non-invasive, and inexpensive point-of-care (POC) diagnostic for malaria followed by therapeutic intervention would improve the ability to control infection in endemic areas. Methods A semi-nested PCR amplification protocol is described for quantitative detection of Plasmodium falciparum and is compared to a traditional nested PCR. The approach uses primers that target the P. falciparum dihydrofolate reductase gene. Results This study demonstrates that it is possible to perform an uninterrupted, asymmetric, semi-nested PCR assay with reduced assay time to detect P. falciparum without compromising the sensitivity and specificity of the assay using saliva as a testing matrix. Conclusions The development of this PCR allows nucleic acid amplification without the need to transfer amplicon from the first PCR step to a second reaction tube with nested primers, thus reducing both the chance of contamination and the time for analysis to < two hours. Analysis of the PCR amplicon yield was adapted to lateral flow detection using the quantitative up-converting phosphor (UCP) reporter technology. This approach provides a basis for migration of the assay to a POC microfluidic format. In addition the assay was successfully evaluated with oral samples. Oral fluid collection provides a simple non-invasive method to collect clinical samples. PMID:23433252

Inner pressure characterization of a sealed nickel-metal hydride cell

NASA Astrophysics Data System (ADS)

Cuscueta, D. J.; Salva, H. R.; Ghilarducci, A. A.

This paper studies the electrochemical behaviour of the pressure inside a sealed Ni-MH cell due to gases evolved under different charge/discharge currents and states of charge (SOC). The work is focused to determine the best procedure to get fast charge and long cycle life without detrimental effects on the battery and possible hazards affecting the safety of the user. The device was studied under a wide range of charge current (0.1-5 C), establishing that optimum conditions to minimize the inner pressure during uninterrupted use are obtained if either charge rates up to 0.5 C or higher rates not surpassing 90% of the nominal capacity are employed. Charge times corresponding to the range between 80% and 130% of the nominal capacity were also tested, analyzing the effect of overcharges on inner pressure, discharge capacity, efficiency and integrity of the cell. It was verified that charging the cell up to 130% at 2 C rate reaches an inner pressure 5 times higher than that obtained at 0.5 C. High rate discharge was also characterized at uninterrupted use of the cell, demonstrating the importance of the cut-off discharge criterion at high rates, to avoid the inner gases accumulation due to incomplete discharge of electrodes and overcharge in a following electrochemical cycle.

Performance Characteristic Mems-Based IMUs for UAVs Navigation

NASA Astrophysics Data System (ADS)

Mohamed, H. A.; Hansen, J. M.; Elhabiby, M. M.; El-Sheimy, N.; Sesay, A. B.

2015-08-01

Accurate 3D reconstruction has become essential for non-traditional mapping applications such as urban planning, mining industry, environmental monitoring, navigation, surveillance, pipeline inspection, infrastructure monitoring, landslide hazard analysis, indoor localization, and military simulation. The needs of these applications cannot be satisfied by traditional mapping, which is based on dedicated data acquisition systems designed for mapping purposes. Recent advances in hardware and software development have made it possible to conduct accurate 3D mapping without using costly and high-end data acquisition systems. Low-cost digital cameras, laser scanners, and navigation systems can provide accurate mapping if they are properly integrated at the hardware and software levels. Unmanned Aerial Vehicles (UAVs) are emerging as a mobile mapping platform that can provide additional economical and practical advantages. However, such economical and practical requirements need navigation systems that can provide uninterrupted navigation solution. Hence, testing the performance characteristics of Micro-Electro-Mechanical Systems (MEMS) or low cost navigation sensors for various UAV applications is important research. This work focuses on studying the performance characteristics under different manoeuvres using inertial measurements integrated with single point positioning, Real-Time-Kinematic (RTK), and additional navigational aiding sensors. Furthermore, the performance of the inertial sensors is tested during Global Positioning System (GPS) signal outage.

Computer hardware for radiologists: Part 2

PubMed Central

Indrajit, IK; Alam, A

2010-01-01

Computers are an integral part of modern radiology equipment. In the first half of this two-part article, we dwelt upon some fundamental concepts regarding computer hardware, covering components like motherboard, central processing unit (CPU), chipset, random access memory (RAM), and memory modules. In this article, we describe the remaining computer hardware components that are of relevance to radiology. “Storage drive” is a term describing a “memory” hardware used to store data for later retrieval. Commonly used storage drives are hard drives, floppy drives, optical drives, flash drives, and network drives. The capacity of a hard drive is dependent on many factors, including the number of disk sides, number of tracks per side, number of sectors on each track, and the amount of data that can be stored in each sector. “Drive interfaces” connect hard drives and optical drives to a computer. The connections of such drives require both a power cable and a data cable. The four most popular “input/output devices” used commonly with computers are the printer, monitor, mouse, and keyboard. The “bus” is a built-in electronic signal pathway in the motherboard to permit efficient and uninterrupted data transfer. A motherboard can have several buses, including the system bus, the PCI express bus, the PCI bus, the AGP bus, and the (outdated) ISA bus. “Ports” are the location at which external devices are connected to a computer motherboard. All commonly used peripheral devices, such as printers, scanners, and portable drives, need ports. A working knowledge of computers is necessary for the radiologist if the workflow is to realize its full potential and, besides, this knowledge will prepare the radiologist for the coming innovations in the ‘ever increasing’ digital future. PMID:21423895

Arcus: the x-ray grating spectrometer explorer

NASA Astrophysics Data System (ADS)

Smith, R. K.; Abraham, M. H.; Allured, R.; Bautz, M.; Bookbinder, J.; Bregman, J. N.; Brenneman, L.; Brickhouse, N. S.; Burrows, D. N.; Burwitz, V.; Carvalho, R.; Cheimets, P. N.; Costantini, E.; Dawson, S.; DeRoo, C.; Falcone, A.; Foster, A. R.; Grant, C. E.; Heilmann, R. K.; Hertz, E.; Hine, B.; Huenemoerder, D.; Kaastra, J. S.; Madsen, K. K.; McEntaffer, R. L.; Miller, E. D.; Miller, J.; Morse, E.; Mushotzky, R.; Nandra, K.; Nowak, M.; Paerels, F.; Petre, R.; Plice, L.; Poppenhaeger, K.; Ptak, A.; Reid, P.; Sanders, J.; Schattenburg, M. L.; Schulz, N.; Smale, A.; Temi, P.; Valencic, L.; Walker, S.; Willingale, R.; Wilms, J.; Wolk, S. J.

2016-07-01

Arcus will be proposed to the NASA Explorer program as a free-flying satellite mission that will enable high-resolution soft X-ray spectroscopy (8-50) with unprecedented sensitivity - effective areas of >500 sq cm and spectral resolution >2500. The Arcus key science goals are (1) to determine how baryons cycle in and out of galaxies by measuring the effects of structure formation imprinted upon the hot gas that is predicted to lie in extended halos around galaxies, groups, and clusters, (2) to determine how black holes influence their surroundings by tracing the propagation of out-flowing mass, energy and momentum from the vicinity of the black hole out to large scales and (3) to understand how accretion forms and evolves stars and circumstellar disks by observing hot infalling and outflowing gas in these systems. Arcus relies upon grazing-incidence silicon pore X-ray optics with the same 12m focal length (achieved using an extendable optical bench) that will be used for the ESA Athena mission. The focused X-rays from these optics will then be diffracted by high-efficiency off-plane reflection gratings that have already been demonstrated on sub-orbital rocket flights, imaging the results with flight-proven CCD detectors and electronics. The power and telemetry requirements on the spacecraft are modest. The majority of mission operations will not be complex, as most observations will be long ( 100 ksec), uninterrupted, and pre-planned, although there will be limited capabilities to observe targets of opportunity, such as tidal disruption events or supernovae with a 3-5 day turnaround. After the end of prime science, we plan to allow guest observations to maximize the science return of Arcus to the community.

Arcus: The X-Ray Grating Spectrometer Explorer

NASA Technical Reports Server (NTRS)

Smith, R. K.; Abraham, M. H.; Allured, R.; Bautz, M.; Bookbinder, J.; Bregman, J. N.; Brenneman, L.; Brickhouse, N. S.; Burrows, D. N.; Burwitz, V.;

Computer hardware for radiologists: Part 2.

PubMed

Indrajit, Ik; Alam, A

2010-11-01

Computers are an integral part of modern radiology equipment. In the first half of this two-part article, we dwelt upon some fundamental concepts regarding computer hardware, covering components like motherboard, central processing unit (CPU), chipset, random access memory (RAM), and memory modules. In this article, we describe the remaining computer hardware components that are of relevance to radiology. "Storage drive" is a term describing a "memory" hardware used to store data for later retrieval. Commonly used storage drives are hard drives, floppy drives, optical drives, flash drives, and network drives. The capacity of a hard drive is dependent on many factors, including the number of disk sides, number of tracks per side, number of sectors on each track, and the amount of data that can be stored in each sector. "Drive interfaces" connect hard drives and optical drives to a computer. The connections of such drives require both a power cable and a data cable. The four most popular "input/output devices" used commonly with computers are the printer, monitor, mouse, and keyboard. The "bus" is a built-in electronic signal pathway in the motherboard to permit efficient and uninterrupted data transfer. A motherboard can have several buses, including the system bus, the PCI express bus, the PCI bus, the AGP bus, and the (outdated) ISA bus. "Ports" are the location at which external devices are connected to a computer motherboard. All commonly used peripheral devices, such as printers, scanners, and portable drives, need ports. A working knowledge of computers is necessary for the radiologist if the workflow is to realize its full potential and, besides, this knowledge will prepare the radiologist for the coming innovations in the 'ever increasing' digital future.

Through the Looking GLASS: HST Spectroscopy of Faint Galaxies Lensed by the Frontier Fields Cluster MACSJ0717.5+3745

NASA Astrophysics Data System (ADS)

Schmidt, K. B.; Treu, T.; Brammer, G. B.; Bradač, M.; Wang, X.; Dijkstra, M.; Dressler, A.; Fontana, A.; Gavazzi, R.; Henry, A. L.; Hoag, A.; Jones, T. A.; Kelly, P. L.; Malkan, M. A.; Mason, C.; Pentericci, L.; Poggianti, B.; Stiavelli, M.; Trenti, M.; von der Linden, A.; Vulcani, B.

2014-02-01

The Grism Lens-Amplified Survey from Space (GLASS) is a Hubble Space Telescope (HST) Large Program, which will obtain 140 orbits of grism spectroscopy of the core and infall regions of 10 galaxy clusters, selected to be among the very best cosmic telescopes. Extensive HST imaging is available from many sources including the CLASH and Frontier Fields programs. We introduce the survey by analyzing spectra of faint multiply-imaged galaxies and z >~ 6 galaxy candidates obtained from the first 7 orbits out of 14 targeting the core of the Frontier Fields cluster MACSJ0717.5+3745. Using the G102 and G141 grisms to cover the wavelength range 0.8-1.7 μm, we confirm four strongly lensed systems by detecting emission lines in each of the images. For the 9 z >~ 6 galaxy candidates clear from contamination, we do not detect any emission lines down to a 7 orbit 1σ noise level of ~5 × 10-18 erg s-1 cm-2. Taking lensing magnification into account, our flux sensitivity reaches ~0.2-5 × 10-18 erg s-1cm-2. These limits over an uninterrupted wavelength range rule out the possibility that the high-z galaxy candidates are instead strong line emitters at lower redshift. These results show that by means of careful modeling of the background—and with the assistance of lensing magnification—interesting flux limits can be reached for large numbers of objects, avoiding pre-selection and the wavelength restrictions inherent to ground-based multi-slit spectroscopy. These observations confirm the power of slitless HST spectroscopy even in fields as crowded as a cluster core.

Frances Keesler Graham (1918-2013).

PubMed

Berg, W Keith

2014-09-01

Frances Keesler Graham, noted psychophysiologist and developmental researcher, died on April 16, 2013. Fran was born in Canastota, New York, on August 1, 1918. Fran's high-quality research, her success in obtaining 39 years of uninterrupted funding, and the very high regard in which she was held among her colleagues led to numerous awards and honors. Fran was demanding but equally willing to provide extensive assistance to students willing to work hard. (c) 2014 APA, all rights reserved.

Design and implementation of an automated compound management system in support of lead optimization.

PubMed

Quintero, Catherine; Kariv, Ilona

2009-06-01

To meet the needs of the increasingly rapid and parallelized lead optimization process, a fully integrated local compound storage and liquid handling system was designed and implemented to automate the generation of assay-ready plates directly from newly submitted and cherry-picked compounds. A key feature of the system is the ability to create project- or assay-specific compound-handling methods, which provide flexibility for any combination of plate types, layouts, and plate bar-codes. Project-specific workflows can be created by linking methods for processing new and cherry-picked compounds and control additions to produce a complete compound set for both biological testing and local storage in one uninterrupted workflow. A flexible cherry-pick approach allows for multiple, user-defined strategies to select the most appropriate replicate of a compound for retesting. Examples of custom selection parameters include available volume, compound batch, and number of freeze/thaw cycles. This adaptable and integrated combination of software and hardware provides a basis for reducing cycle time, fully automating compound processing, and ultimately increasing the rate at which accurate, biologically relevant results can be produced for compounds of interest in the lead optimization process.

An Anomaly Correlation Skill Score for the Evaluation of the Performance of Hyperspectral Infrared Sounders

NASA Technical Reports Server (NTRS)

Aumann, Hartmut H.; Manning, Evan; Barnet, Chris; Maddy, Eric; Blackwell, William

2009-01-01

With the availability of very accurate forecasts, the metric of accuracy alone for the evaluation of the performance of a retrieval system can produce misleading results. A useful characterization of the quality of a retrieval system and its potential to contribute to an improved weather forecast is its skill, which we define as the ability to make retrievals of geophysical parameters which are closer to the truth than the six hour forecast, when the truth differs significantly from the forecast. We illustrate retrieval skill using one day of AMSU and AIRS data with three different retrieval algorithms, which result in retrievals for more than 90% of the potential retrievals under clear and cloudy conditions. Two of the three algorithms have better than 1 K rms "RAOB quality" accuracy on the troposphere, but only one has skill between 900 and 100 mb. AIRS was launched on the EOS Aqua spacecraft in May 2002 into a 705 km polar sun-synchronous orbit with accurately maintained 1:30 PM ascending node. Essentially uninterrupted data are freely available since September 2002.

Cytotoxicity and mitogenicity assays with real-time and label-free monitoring of human granulosa cells with an impedance-based signal processing technology intergrating micro-electronics and cell biology.

PubMed

Oktem, Ozgur; Bildik, Gamze; Senbabaoglu, Filiz; Lack, Nathan A; Akin, Nazli; Yakar, Feridun; Urman, Defne; Guzel, Yilmaz; Balaban, Basak; Iwase, Akira; Urman, Bulent

2016-04-01

A recently developed technology (xCelligence) integrating micro-electronics and cell biology allows real-time, uninterrupted and quantitative analysis of cell proliferation, viability and cytotoxicity by measuring the electrical impedance of the cell population in the wells without using any labeling agent. In this study we investigated if this system is a suitable model to analyze the effects of mitogenic (FSH) and cytotoxic (chemotherapy) agents with different toxicity profiles on human granulosa cells in comparison to conventional methods of assessing cell viability, DNA damage, apoptosis and steroidogenesis. The system generated the real-time growth curves of the cells, and determined their doubling times, mean cell indices and generated dose-response curves after exposure to cytotoxic and mitogenic stimuli. It accurately predicted the gonadotoxicity of the drugs and distinguished less toxic agents (5-FU and paclitaxel) from more toxic ones (cisplatin and cyclophosphamide). This platform can be a useful tool for specific end-point assays in reproductive toxicology. Copyright © 2015 Elsevier Inc. All rights reserved.

Contingency plan to provide safe drinking water for the city of Milan, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Talbot, J.J.; Brew, P.

1994-12-31

The city of Milan, in western Tennessee, supplies drinking water to approximately 4,000 customers. Environmental investigations conducted by the US Army have detected low concentrations of RDX, a compound used in the manufacture of explosives, in two of the three city water supply wells. The RDX is traceable to the Milan Army Ammunition Plant nearby. The levels of RDX are being monitored and current trends indicate that levels in the wells will exceed the EPA Health Advisory Limits in the near term. In order to ensure an uninterrupted supply of acceptable quality drinking water for the city residents, the Armymore » prepared and is implementing a Contingency Plan. The plan evaluated remedial alternatives to be implemented once a trigger level of RDX is reached, including institutional controls, installation of an RDX treatment system for the water supply system, and construction of a new well field. Institutional controls include: shutting down existing wells; continued monitoring; and promulgation of ground water ordinances. Treatment technologies evaluated include: ultraviolet light and hydrogen peroxide; or removal using granular activated carbon.« less

Revealing the secret life of pre-implantation embryos by time-lapse monitoring: A review

PubMed Central

Faramarzi, Azita; Khalili, Mohammad Ali; Micara, Giulietta; Agha-Rahimi, Azam

2017-01-01

High implantation success following in vitro fertilization cycles are achieved via the transfer of embryos with the highest developmental competence. Multiple pregnancies as a result of the transfer of several embryos per cycle accompany with various complication. Thus, single-embryo transfer (SET) is the preferred practice in assisted reproductive technique (ART) treatment. In order to improve the pregnancy rate for SET, embryologists need reliable biomarkers to aid their selection of embryos with the highest developmental potential. Time-lapse technology is a noninvasive alternative conventional microscopic assessment. It provides uninterrupted and continues the survey of embryo development to transfer day. Today, there are four time-lapse systems that are commercially available for ART centers. In world and Iran, the first time lapse babies were born in 2010 and 2015, respectively, conceived by SET. Here, we review the use of time-lapse monitoring in the observation of embryogenesis as well as its role in SET. Although, the findings from our review support common use of time-lapse monitoring in ART centers; but, future large studies assessing this system in well-designed trials are necessary. PMID:28744520

Effect of pre-procedural interrupted apixaban on heparin anticoagulation during catheter ablation for atrial fibrillation: a prospective observational study.

PubMed

Bin Abdulhak, Aref A; Kennedy, Kevin F; Gupta, Sanjaya; Giocondo, Michael; Ramza, Brian; Wimmer, Alan P

2015-11-01

Effective intraprocedural anticoagulation is considered essential to minimize the risk of thromboembolism in catheter ablation (CA) of atrial fibrillation (AF). The effect of interrupted apixaban on intraprocedural heparin dosing requirements and levels of achieved anticoagulation with heparin has not been well studied. The purpose of the present study was to compare heparin administration and activated clotted times (ACTs) for patients undergoing CA for AF treated with interrupted apixaban before the procedure with patients on uninterrupted warfarin. Consecutive patients undergoing CA for AF treated with interrupted apixaban or uninterrupted warfarin were prospectively enrolled. Heparin administration determined by a standard protocol and normalized to patient weight and procedure duration, as well as rapidity, and degree of anticoagulation with heparin (as measured by mean ACT, peak ACT, time to ACT ≥300 s, and time to ACT ≥350 s) were compared between the groups. Forty-eight patients were enrolled (25 apixaban and 23 warfarin). Heparin administered by bolus (51.3 ± 21.5 vs 27.8 ± 9.6 units/kg/h; p < 0.001) and mean heparin drip rate (25.3 ± 3.6 vs 20.7 ± 2.4 units/kg/h; p < 0.001) were significantly higher in the apixaban group compared to the warfarin group. Despite greater heparin administration, apixaban patients achieved a significantly lower mean ACT (332.3 ± 17.0 vs 384.5 ± 53.9; p < 0.001) and peak ACT (369.5 ± 22.6 vs 432.3 ± 75.8, p < 0.001) compared to the warfarin group. The time to ACT ≥350 s (66.7 ± 35.8 vs 26.9 ± 34.0; p < 0.001) was significantly longer for apixaban-treated patients. Outcome differences persisted after analysis using linear models and Cox proportional hazard regression with adjustment for propensity scores. A standard intraprocedural heparin protocol results in delayed and lower levels of anticoagulation as measured by the ACT for interrupted apixaban-treated patients in comparison to those on uninterrupted warfarin during CA of AF.

The Coast Artillery Journal. Volume 73, Number 3, September 1930

DTIC Science & Technology

1930-09-01

Chinese history can- not fail to notice that military operations in that country tend to fall into definite strategic patterns. It is believed that...there rises a mountain barrier that, practically uninterrupted, sweeps ,vest, then north, then .east again in a sprawling semicircle. 1Ioreover, this...swept from the Great Plain. In modern times its importance has increased with the rise of the port of Shanghai; which lies, so to speak, under its guns

Slow and fast fatigable frog muscle fibres: electrophysiological and histochemical characteristics.

PubMed

Vydevska-Chichova, M; Mileva, K; Todorova, R; Dimitrova, M; Radicheva, N

2005-12-01

Continuous activity of isolated frog gastrocnemius muscle fibres provoked by repetitive stimulation of 5 Hz was used as an experimental model for fatigue development in different fibre types. Parameter changes of the elicited intracellular action potentials and mechanical twitches during the period of uninterrupted activity were used as criteria for fatigue evaluation. Slow fatigable muscle fibre (SMF) and fast fatigable muscle fibre (FMF) types were distinguished depending on the duration of their uninterrupted activity, which was significantly longer in SMFs than in FMFs. The normalized changes of action potential amplitude and duration were significantly smaller in FMFs than in SMFs. The average twitch force and velocity of contraction and relaxation were significantly higher in FMFs than in SMFs. Myosin ATPase (mATPase) and succinate dehydrogenase activity were studied by histochemical assessment in order to validate the fibre type classification based on their electrophysiological characteristics. Based on the relative mATPase reactivity, the fibres of the studied muscle were classified as one of five different types (1-2, 2, 2-3, 3 and tonic). Smaller sized fibres (tonic and type 3) expressed higher succinate dehydrogenase activity than larger sized fibres (type 1-2, 2), which is related to the fatigue resistance. The differences between fatigue development in SMFs and FMFs during continuous activity were associated with fibre-type specific mATPase and succinate dehydrogenase activity.

Computational fluid dynamics (CFD) investigation of impacts of an obstruction on airflow in underground mines.

PubMed

Zhou, L; Goodman, G; Martikainen, A

2013-01-01

Continuous airflow monitoring can improve the safety of the underground work force by ensuring the uninterrupted and controlled distribution of mine ventilation to all working areas. Air velocity measurements vary significantly and can change rapidly depending on the exact measurement location and, in particular, due to the presence of obstructions in the air stream. Air velocity must be measured at locations away from obstructions to avoid the vortices and eddies that can produce inaccurate readings. Further, an uninterrupted measurement path cannot always be guaranteed when using continuous airflow monitors due to the presence of nearby equipment, personnel, roof falls and rib rolls. Effective use of these devices requires selection of a minimum distance from an obstacle, such that an air velocity measurement can be made but not affected by the presence of that obstacle. This paper investigates the impacts of an obstruction on the behavior of downstream airflow using a numerical CFD model calibrated with experimental test results from underground testing. Factors including entry size, obstruction size and the inlet or incident velocity are examined for their effects on the distributions of airflow around an obstruction. A relationship is developed between the minimum measurement distance and the hydraulic diameters of the entry and the obstruction. A final analysis considers the impacts of continuous monitor location on the accuracy of velocity measurements and on the application of minimum measurement distance guidelines.

Computational fluid dynamics (CFD) investigation of impacts of an obstruction on airflow in underground mines

PubMed Central

Zhou, L.; Goodman, G.; Martikainen, A.

2015-01-01

Continuous airflow monitoring can improve the safety of the underground work force by ensuring the uninterrupted and controlled distribution of mine ventilation to all working areas. Air velocity measurements vary significantly and can change rapidly depending on the exact measurement location and, in particular, due to the presence of obstructions in the air stream. Air velocity must be measured at locations away from obstructions to avoid the vortices and eddies that can produce inaccurate readings. Further, an uninterrupted measurement path cannot always be guaranteed when using continuous airflow monitors due to the presence of nearby equipment, personnel, roof falls and rib rolls. Effective use of these devices requires selection of a minimum distance from an obstacle, such that an air velocity measurement can be made but not affected by the presence of that obstacle. This paper investigates the impacts of an obstruction on the behavior of downstream airflow using a numerical CFD model calibrated with experimental test results from underground testing. Factors including entry size, obstruction size and the inlet or incident velocity are examined for their effects on the distributions of airflow around an obstruction. A relationship is developed between the minimum measurement distance and the hydraulic diameters of the entry and the obstruction. A final analysis considers the impacts of continuous monitor location on the accuracy of velocity measurements and on the application of minimum measurement distance guidelines. PMID:26388684

Why do female Callosobruchus maculatus kick their mates?

PubMed

van Lieshout, Emile; McNamara, Kathryn B; Simmons, Leigh W

2014-01-01

Sexual conflict is now recognised as an important driver of sexual trait evolution. However, due to their variable outcomes and effects on other fitness components, the detection of sexual conflicts on individual traits can be complicated. This difficulty is exemplified in the beetle Callosobruchus maculatus, where longer matings increase the size of nutritious ejaculates but simultaneously reduce female future receptivity. While previous studies show that females gain direct benefits from extended mating duration, females show conspicuous copulatory kicking behaviour, apparently to dislodge mating males prematurely. We explore the potential for sexual conflict by comparing several fitness components and remating propensity in pairs of full sibling females where each female mated with a male from an unrelated pair of full sibling males. For one female, matings were terminated at the onset of kicking, whereas the other's matings remained uninterrupted. While fecundity (number of eggs) was similar between treatments, uninterrupted matings enhanced adult offspring numbers and fractionally also longevity. However, females whose matings were interrupted at the onset of kicking exhibited an increased propensity to remate. Since polyandry can benefit female fitness in this species, we argue that kicking, rather than being maladaptive, may indicate that females prefer remating over increased ejaculate size. It may thus be difficult to assess the presence of sexual conflict over contested traits such as mating duration when females face a trade off between direct benefits gained from one mating and indirect benefits from additional matings.

A 15-minute light pulse during darkness prevents the antigonadotrophic action of afternoon melatonin injections in male hamsters

NASA Astrophysics Data System (ADS)

Reiter, R. J.; Hurlbut, E. C.; King, T. S.; Richardson, B. A.; Vaughan, M. K.; Kosub, K. Y.

1982-12-01

When adult male Syrian hamsters were maintained under 14 h light and 10 h darkness daily (lights on from 0600-2000 h), peak pineal melatonin levels (705 pg/gland) were attained at 0500 h. When the dark phase of the light:dark cycle was interrupted with a 15 min pulse of light from 2300 2315 h (3 h after lights out), the highest melatonin levels achieved was roughly 400 pg/gland. Finally, if the 15 min pulse of light was given at 0200 0215 h (6 h after lights out) the nocturnal rise in pineal melatonin was completely abolished. Having made these observations, a second experiment was designed to determine the ability of afternoon melatonin injections to inhibit reproduction in hamsters kept under an uninterrupted 14∶10 cycle or under the same lighting regimen where the dark phase was interrupted with a 15 min pulse of light (0200 0215 h). In the uninterrupted light:dark schedule the daily afternoon injection of 25 μg melatonin caused the testes and the accessory sex organs to atrophy within 11 weeks. Conversely, if the dark phase was interrupted with light between 0200 0215 h, afternoon melatonin injections were incapable of inhibiting the growth of the reproductive organs. The findings suggest that exogenously administered melatonin normally synergizes with endogenously produced melatonin to cause gonadal involution in hamsters.

The Badger Company conceptual design of a 50 MGD desalination plant. Special report No. 10

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1965-08-01

The objective of this study is to produce a design which advances the technology of seawater conversion and to present the results in a form which can be used by any qualified individual or firm as the basis for an architectural-engineering design. Ground rules furnished by OSW specified that only the desalination section of a dual-purpose power-water plant be considered and that it be designed for a 30-year life. Process and structural design ideas are to be presented in terms of the complete plant concept. The complex is to be located on a typical California coastal site with capital andmore » operating costs based on December, 1964, values. The Badger study considers the Multi-Stage Flash (MSF) process, achieving a minimum overall pressure drop by an uninterrupted flow path of brine and product water through the evaporator flashing area. A performance ratio of 20 pounds of product water per pound of steam yields a calculated water cost of $0.323 per thousand gallons. The specified 30-year write-off at low interest rates allows comparatively high capital expenditures favoring titanium tubing for brine service which contributes to low maintenance and operating costs. (GRA)« less

Arcus: An Overview of the Soft X-ray Grating Explorer

NASA Astrophysics Data System (ADS)

Smith, Randall; Arcus Collaboration

2018-01-01

The Arcus MIDEX Explorer, which NASA selected for a Phase A study in August 2017, provides high-resolution soft X-ray spectroscopy in the 12-50Å bandpass with unprecedented sensitivity. Its capabilities include spectral resolution >2500 and effective areas in the range 200-600 cm^2. The three top science goals for Arcus are (1) to measure the effects of structure formation imprinted upon the hot baryons that are predicted to lie in extended halos around galaxies, groups, and clusters, (2) to trace the propagation of outflowing mass, energy, and momentum from the vicinity of the black hole to extragalactic scales as a measure of their feedback and (3) to explore how stars, circumstellar disks and exoplanet atmospheres form and evolve. Arcus relies upon the same 12m focal length grazing-incidence silicon pore X-ray optics (SPO) that ESA has developed for the Athena mission; the focal length is achieved on orbit via an extendable optical bench. The focused X-rays from these optics are diffracted by high-efficiency Critical-Angle Transmission (CAT) gratings, and the results are imaged with flight-proven CCD detectors and electronics. The power and telemetry requirements on the spacecraft are modest and mission operations are straightforward, as most observations will be long (~100 ksec), uninterrupted, and pre-planned.

Focal-plane electric field sensing with pupil-plane holograms

NASA Astrophysics Data System (ADS)

Por, Emiel H.; Keller, Christoph U.

2016-07-01

The direct detection and spectral characterization of exoplanets requires a coronagraph to suppress the diffracted star light. Amplitude and phase aberrations in the optical train fill the dark zone of the coronagraph with quasi-static speckles that limit the achievable contrast. Focal-plane electric field sensing, such as phase diversity introduced by a deformable mirror (DM), is a powerful tool to minimize this residual star light. The residual electric field can be estimated by sequentially applying phase probes on the DM to inject star light with a well-known amplitude and phase into the dark zone and analyzing the resulting intensity images. The DM can then be used to add light with the same amplitude but opposite phase to destructively interfere with this residual star light. Using a static phase-only pupil-plane element we create holographic copies of the point spread function (PSF), each superimposed with a certain pupil-plane phase probe. We therefore obtain all intensity images simultaneously while still retaining a central, unaltered science PSF. The electric field sensing method only makes use of the holographic copies, allowing for correction of the residual electric field while retaining the central PSF for uninterrupted science data collection. In this paper we demonstrate the feasibility of this method with numerical simulations.

Water-Tree Modelling and Detection for Underground Cables

NASA Astrophysics Data System (ADS)

Chen, Qi

In recent years, aging infrastructure has become a major concern for the power industry. Since its inception in early 20th century, the electrical system has been the cornerstone of an industrial society. Stable and uninterrupted delivery of electrical power is now a base necessity for the modern world. As the times march-on, however, the electrical infrastructure ages and there is the inevitable need to renew and replace the existing system. Unfortunately, due to time and financial constraints, many electrical systems today are forced to operate beyond their original design and power utilities must find ways to prolong the lifespan of older equipment. Thus, the concept of preventative maintenance arises. Preventative maintenance allows old equipment to operate longer and at better efficiency, but in order to implement preventative maintenance, the operators must know minute details of the electrical system, especially some of the harder to assess issues such water-tree. Water-tree induced insulation degradation is a problem typically associated with older cable systems. It is a very high impedance phenomenon and it is difficult to detect using traditional methods such as Tan-Delta or Partial Discharge. The proposed dissertation studies water-tree development in underground cables, potential methods to detect water-tree location and water-tree severity estimation. The dissertation begins by developing mathematical models of water-tree using finite element analysis. The method focuses on surface-originated vented tree, the most prominent type of water-tree fault in the field. Using the standard operation parameters of North American electrical systems, the water-tree boundary conditions are defined. By applying finite element analysis technique, the complex water-tree structure is broken down to homogeneous components. The result is a generalized representation of water-tree capacitance at different stages of development. The result from the finite element analysis is used to model water-tree in large system. Both empirical measurements and the mathematical model show that the impedance of early-stage water-tree is extremely large. As the result, traditional detection methods such Tan-Delta or Partial Discharge are not effective due to the excessively high accuracy requirement. A high-frequency pulse detection method is developed instead. The water-tree impedance is capacitive in nature and it can be reduced to manageable level by high-frequency inputs. The method is able to determine the location of early-stage water-tree in long-distance cables using economically feasible equipment. A pattern recognition method is developed to estimate the severity of water-tree using its pulse response from the high-frequency test method. The early-warning system for water-tree appearance is a tool developed to assist the practical implementation of the high-frequency pulse detection method. Although the equipment used by the detection method is economically feasible, it is still a specialized test and not designed for constant monitoring of the system. The test also place heavy stress on the cable and it is most effective when the cable is taken offline. As the result, utilities need a method to estimate the likelihood of water-tree presence before subjecting the cable to the specialized test. The early-warning system takes advantage of naturally occurring high-frequency events in the system and uses a deviation-comparison method to estimate the probability of water-tree presence on the cable. If the likelihood is high, then the utility can use the high-frequency pulse detection method to obtain accurate results. Specific pulse response patterns can be used to calculate the capacitance of water-tree. The calculated result, however, is subjected to margins of error due to limitations from the real system. There are both long-term and short-term methods to improve the accuracy. Computation algorithm improvement allows immediate improvement on accuracy of the capacitance estimation. The probability distribution of the calculation solution showed that improvements in waveform time-step measurement allow fundamental improves to the overall result.

Infrared solar physics from the South Pole

NASA Technical Reports Server (NTRS)

Deming, Drake

1989-01-01

Infrared (IR) observations of the sun could greatly benefit from the quality of the South Pole as an IR site, and the potential for multi-day sequences of uninterrupted observations. A nearly continuous picture of the evolution of the magnetic field in solar active regions could be obtained using vector magnetographs, especially vector magnetographs which incorporate IR array detectors. Observations of the sun over a range of wavelengths in the IR continuum could also be used to study the vertical propagation characteristics of the solar p-mode oscillations.

Detection of a 9.4 min periodicity in the XMM-Newton and Chandra X-ray light curves of V407 Lup (Nova Lup 2016)

NASA Astrophysics Data System (ADS)

Beardmore, Andy; Dobrotka, Andrej; Ness, Jan-Uwe; Orio, Marina; Osborne, Julian; Page, Kim

2017-09-01

We report on the timing analysis of two long, uninterrupted X-ray observations of V407 Lup (also know as ASASSN-16kt and Nova Lup 2016; see ATel #9538, #9539, #9550, #9554, #9587, #9594 and #9644, #10632, #10722) performed with XMM-Newton for 22,000 s on 2017 March 11 and with the Chandra HRC_s and Low Energy Transmission Grating on 2017 August 30 for 34,000 s.

Environmental Impact Study of the Elm Fork Region of the Trinity River.

DTIC Science & Technology

1972-04-14

uninterruptedly for two to four years would be re- quired. Especially in the latter two realms it is essential to compare annual data for several years in order to...site (Crook, 1952; Crook and Harris, 1953) located in the northeastern part of the sur- veyed area. The Wheeler site essentially has been destroyed...quarrying of raw mate- rial including quartzite and chert. These sites may be of any age for these resources were continually used. 18 oil 031 12 ELM FORK

Determination of Spin Axis Orientation of Geosynchronous Objects Using Space-Based Sensors: An Initial Feasibility Investigation

DTIC Science & Technology

2010-09-01

increased rate of satellite launches over time , and on-orbit incidents such as the Breeze-M explosion in 2007 and the Iridium 33-Cosmos 2251...respect to the observer. The reason that the synodic and sidereal periods differ is that during the time it takes for the satellite to complete one...take ~2 hours to traverse the region, allowing time to collect an uninterrupted sequence of photometry on the objects despite the need for NEOSSat to

Fetal electrocardiographic measurements in the assessment of fetal heart rate variability in the antepartum period.

PubMed

Van Leeuwen, Peter; Werner, Lisa; Hilal, Ziad; Schiermeier, Sven; Hatzmann, Wolfgang; Grönemeyer, Dietrich

2014-03-01

This study examines signal availability in fetal electrocardiogram (FECG) beat-to-beat acquisition and the accuracy of fetal heart rate variability (HRV) analysis in the clinical setting using a commercially available FECG monitor. Signal availability was examined in 130 FECG recordings of 0.3-17.5 h duration collected in 63 fetuses (25th-42nd week of gestation) under uncontrolled conditions. Identification of R-peaks demonstrated a signal loss of 30% ± 24% with 3.6 ± 1.7 signal gaps per minute. Median duration of the gaps within a recording was 1.8 ± 0.2 s. Per hour of recording, 1.8 ± 2.1 episodes of 5 min of uninterrupted data were found. Signal availability improved with gestational age and was poorer in women with high body-mass index. Fetal HRV between weeks 36-42 was examined on the basis of 5 min RR-interval episodes obtained under controlled quiet conditions in 55 FECG compared to 46 high quality fetal magnetocardiograms. There were no differences in RR-interval duration, its standard deviation and low frequency power. However, various measures of short-term HRV were significantly higher in the FECG data: root mean square of successive differences (10.0 ± 1.8 versus 6.6 ± 3.0 ms, p < 0.001, high frequency spectral power (24 ± 12 versus 13 ± 13 ms(2), p < 0.001) and approximate entropy (0.86 ± 0.16 versus 0.73 ± 0.24, p = 0.007). We conclude that, in spite of considerable signal loss, FECG recordings can accurately estimate heart rate and its overall variance. However, measures that quantify short-term beat-to-beat HRV will be compromised due to possible recurring inappropriate detection of single R-peaks.

A green observatory in the Chilean Atacama desert

NASA Astrophysics Data System (ADS)

Ramolla, Michael; Westhues, Christian; Hackstein, Moritz; Haas, Martin; Hodapp, Klaus; Lemke, Roland; Barr Domínguez, Angie; Chini, Rolf; Murphy, Miguel

2016-08-01

Since 2007, the Ruhr-Universität Bochum (RUB) in Germany and Universidad Católica del Norte (UCN) in Chile jointly operate the Universitätssternwarte der Ruhr-Universität Bochum (USB), which is located in direct neighborhood of the future E-ELT of ESO. It is the only observatory powered exclusively by solar panels and wind turbines. Excess power is stored in batteries that allow uninterrupted operation even in windless nights. The scientific equipment consists of three robotic optical telescopes with apertures ranging from 15 cm (RoBoTT) over 25 cm (BESTII) to 40 cm (BMT) and one 80 cm (IRIS) infra-red telescope. The optical telescopes are equipped with Johnson and Sloan broad band filters together with a large number of narrow and intermediate bands. In the infrared, J,H and K filters are available, accompanied by several narrow bands near the K band wavelength. The second Nasmyth focus in the 80 cm telescope feeds a high resolution echelle spectrograph similar to the FEROS instrument of ESO. This variety of instruments has evolved from different collaborations, i.e. with the University of Hawaii (IfA) in the USA, which provided the near-infrared-camera of the IRIS telescope, or with the Deutsches Zentrum für Luft- und Raumfahrt (DLR) in Germany, which provided the BESTII telescope. The highly automatized processes on all telescopes enable a single person to run the whole facility, providing the high cost efficiency required for an university observatory. The excellent site conditions allow projects that require daily observations of astronomical objects over epochs of several months or years. Here we report on such studies of young stellar objects from the Bochum Galactic Disk Survey, the multiplicity of stars, quasar variability or the hunt for exo-planets.

Redundancy of Supply in the International Nuclear Fuel Fabrication Market: Are Fabrication Services Assured?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seward, Amy M.; Toomey, Christopher; Ford, Benjamin E.

2011-11-14

For several years, Pacific Northwest National Laboratory (PNNL) has been assessing the reliability of nuclear fuel supply in support of the U.S. Department of Energy/National Nuclear Security Administration. Three international low enriched uranium reserves, which are intended back up the existing and well-functioning nuclear fuel market, are currently moving toward implementation. These backup reserves are intended to provide countries credible assurance that of the uninterrupted supply of nuclear fuel to operate their nuclear power reactors in the event that their primary fuel supply is disrupted, whether for political or other reasons. The efficacy of these backup reserves, however, may bemore » constrained without redundant fabrication services. This report presents the findings of a recent PNNL study that simulated outages of varying durations at specific nuclear fuel fabrication plants. The modeling specifically enabled prediction and visualization of the reactors affected and the degree of fuel delivery delay. The results thus provide insight on the extent of vulnerability to nuclear fuel supply disruption at the level of individual fabrication plants, reactors, and countries. The simulation studies demonstrate that, when a reasonable set of qualification criteria are applied, existing fabrication plants are technically qualified to provide backup fabrication services to the majority of the world's power reactors. The report concludes with an assessment of the redundancy of fuel supply in the nuclear fuel market, and a description of potential extra-market mechanisms to enhance the security of fuel supply in cases where it may be warranted. This report is an assessment of the ability of the existing market to respond to supply disruptions that occur for technical reasons. A forthcoming report will address political disruption scenarios.« less

Preprocessing for Eddy Dissipation Rate and TKE Profile Generation

NASA Technical Reports Server (NTRS)

Zak, J. Allen; Rodgers, William G., Jr.; McKissick, Burnell T. (Technical Monitor)

2001-01-01

The Aircraft Vortex Spacing System (AVOSS), a set of algorithms to determine aircraft spacing according to wake vortex behavior prediction, requires turbulence profiles to appropriately determine arrival and departure aircraft spacing. The ambient atmospheric turbulence profile must always be produced, even if the result is an arbitrary (canned) profile. The original turbulence profile code was generated By North Carolina State University and used in a non-real-time environment in the past. All the input parameters could be carefully selected and screened prior to input. Since this code must run in real-time using actual measurements in the field as input, it became imperative to begin a data checking and screening process as part of the real-time implementation. The process described herein is a step towards ensuring that the best possible turbulence profile is always provided to AVOSS. Data fill-ins, constant profiles and arbitrary profiles are used only as a last resort, but are essential to ensure uninterrupted application of AVOSS.

The role of early detection and treatment in malaria elimination.

PubMed

Landier, Jordi; Parker, Daniel M; Thu, Aung Myint; Carrara, Verena I; Lwin, Khin Maung; Bonnington, Craig A; Pukrittayakamee, Sasithon; Delmas, Gilles; Nosten, François H

2016-07-15

Falciparum malaria persists in hard-to-reach areas or demographic groups that are missed by conventional healthcare systems but could be reached by trained community members in a malaria post (MP). The main focus of a MP is to provide uninterrupted and rapid access to rapid diagnostic tests (RDTs) and artemisinin-based combination therapy (ACT) too all inhabitants of a village. RDTs allow trained community members to perform malaria diagnosis accurately and prescribe appropriate treatment, reducing as much as possible any delay between the onset of fever and treatment. Early treatment with ACT and with a low-dose of primaquine prevents further transmission from human to mosquito. A functioning MP represents an essential component of any malaria elimination strategy. Implementing large-scale, high-coverage, community-based early diagnosis and treatment through MPs requires few technological innovations but relies on a very well structured organization able to train, supervise and supply MPs, to monitor activity and to perform strict malaria surveillance.

Early Science Results from SOFIA, the Worlds Largest Airborne Observatory

NASA Astrophysics Data System (ADS)

De Buizer, J.

2012-09-01

The Stratospheric Observatory for Infrared Astronomy, or SOFIA, is the largest flying observatory ever built, consisting of a 2.7-meter diameter telescope embedded in a modified Boeing 747-SP aircraft. SOFIA is a joint project between NASA and the German Aerospace Center Deutsches Zentrum fur Luft und-Raumfahrt. By flying at altitudes up to 45000 feet, the observatory gets above 99.9% of the infrared-absorbing water vapor in the Earth's atmosphere. This opens up an almost uninterrupted wavelength range from 0.3-1600 microns that is in large part obscured from ground based observatories. Since its 'Initial Science Flight' in December 2010, SOFIA has flown several dozen science flights, and has observed a wide array of objects from Solar System bodies, to stellar nurseries, to distant galaxies. This talk will review some of the exciting new science results from these first flights which were made by three instruments: the mid-infrared camera FORCAST, the far-infrared heterodyne spectrometer GREAT, and the optical occultation photometer HIPO.

Why Do Female Callosobruchus maculatus Kick Their Mates?

PubMed Central

van Lieshout, Emile; McNamara, Kathryn B.; Simmons, Leigh W.

2014-01-01

Sexual conflict is now recognised as an important driver of sexual trait evolution. However, due to their variable outcomes and effects on other fitness components, the detection of sexual conflicts on individual traits can be complicated. This difficulty is exemplified in the beetle Callosobruchus maculatus, where longer matings increase the size of nutritious ejaculates but simultaneously reduce female future receptivity. While previous studies show that females gain direct benefits from extended mating duration, females show conspicuous copulatory kicking behaviour, apparently to dislodge mating males prematurely. We explore the potential for sexual conflict by comparing several fitness components and remating propensity in pairs of full sibling females where each female mated with a male from an unrelated pair of full sibling males. For one female, matings were terminated at the onset of kicking, whereas the other’s matings remained uninterrupted. While fecundity (number of eggs) was similar between treatments, uninterrupted matings enhanced adult offspring numbers and fractionally also longevity. However, females whose matings were interrupted at the onset of kicking exhibited an increased propensity to remate. Since polyandry can benefit female fitness in this species, we argue that kicking, rather than being maladaptive, may indicate that females prefer remating over increased ejaculate size. It may thus be difficult to assess the presence of sexual conflict over contested traits such as mating duration when females face a trade off between direct benefits gained from one mating and indirect benefits from additional matings. PMID:24752530

A novel concept for the surgical anatomy of the perineal body.

PubMed

Shafik, Ahmed; Sibai, Olfat El; Shafik, Ali A; Shafik, Ismail A

2007-12-01

Perineal body is considered by investigators as a fibromuscular structure that is the site of insertion of perineal muscles. We investigated the hypothesis that perineal body is the site across which perineal muscles pass uninterrupted from one side to the other. Perineal body was studied in 56 cadaveric specimens (46 adults, 10 neonatal deaths) by direct dissection with the help of magnifying loupe, fine surgical instruments, and bright light. Perineal body consisted of three layers: 1) superficial layer, which consisted of fleshy fibers of the external anal sphincter extending across perineal body to become the bulbospongiosus muscle; 2) tendinous extension of superficial transverse perineal muscle crossing perineal body to contralateral superficial transverse perineal muscle, with which it formed a criss-cross pattern; and 3) tendinous fibers of the deep transverse perineal muscle; the fibers crossing perineal body decussated in criss-cross pattern with the contralateral deep transverse perineal muscle. A relation of levator ani or puborectalis muscles to perineal body could not be identified. Perineal body (central perineal tendon) is not the site of insertion of perineal muscles but the site along which muscle fibers of these muscles and the external anal sphincter pass uninterrupted from one side to the other. Such a free passage from one muscle to the other seems to denote a "digastric pattern" for the perineal muscles. Perineal body is subjected to injury or continuous intra-abdominal pressure variations, which may eventually result in perineocele, enterocele, or sigmoidocele.

Endovascular treatment of iliofemoral deep vein thrombosis in pregnancy using US-guided percutaneous aspiration thrombectomy.

PubMed

Gedikoglu, Murat; Oguzkurt, Levent

2017-01-01

We aimed to describe ultrasonography (US)-guided percutaneous aspiration thrombectomy in pregnant women with iliofemoral deep vein thrombosis. This study included nine pregnant women with acute and subacute iliofemoral deep vein thrombosis, who were severe symptomatic cases with massive swelling and pain of the leg. Patients were excluded from the study if they had only femoropopliteal deep vein thrombosis or mild symptoms of deep vein thrombosis. US-guided percutaneous aspiration thrombectomy was applied to achieve thrombus removal and uninterrupted venous flow. The treatment was considered successful if there was adequate venous patency and symptomatic relief. Complete or significant thrombus removal and uninterrupted venous flow from the puncture site up to the iliac veins were achieved in all patients at first intervention. Complete relief of leg pain was achieved immediately in seven patients (77.8%). Two patients (22.2%) had a recurrence of thrombosis in the first week postintervention. One of them underwent a second intervention, where percutaneous aspiration thrombectomy was performed again with successful removal of thrombus and establishment of in line flow. Two patients were lost to follow-up after birth. None of the remaining seven patients had rethrombosis throughout the postpartum period. Symptomatic relief was detected clinically in these patients. Endovascular treatment with US-guided percutaneous aspiration thrombectomy can be considered as a safe and effective way to remove thrombus from the deep veins in pregnant women with acute and subacute iliofemoral deep vein thrombosis.

Endovascular treatment of iliofemoral deep vein thrombosis in pregnancy using US-guided percutaneous aspiration thrombectomy

PubMed Central

Gedikoglu, Murat; Oguzkurt, Levent

2017-01-01

PURPOSE We aimed to describe ultrasonography (US)-guided percutaneous aspiration thrombectomy in pregnant women with iliofemoral deep vein thrombosis. METHODS This study included nine pregnant women with acute and subacute iliofemoral deep vein thrombosis, who were severe symptomatic cases with massive swelling and pain of the leg. Patients were excluded from the study if they had only femoropopliteal deep vein thrombosis or mild symptoms of deep vein thrombosis. US-guided percutaneous aspiration thrombectomy was applied to achieve thrombus removal and uninterrupted venous flow. The treatment was considered successful if there was adequate venous patency and symptomatic relief. RESULTS Complete or significant thrombus removal and uninterrupted venous flow from the puncture site up to the iliac veins were achieved in all patients at first intervention. Complete relief of leg pain was achieved immediately in seven patients (77.8%). Two patients (22.2%) had a recurrence of thrombosis in the first week postintervention. One of them underwent a second intervention, where percutaneous aspiration thrombectomy was performed again with successful removal of thrombus and establishment of in line flow. Two patients were lost to follow-up after birth. None of the remaining seven patients had rethrombosis throughout the postpartum period. Symptomatic relief was detected clinically in these patients. CONCLUSION Endovascular treatment with US-guided percutaneous aspiration thrombectomy can be considered as a safe and effective way to remove thrombus from the deep veins in pregnant women with acute and subacute iliofemoral deep vein thrombosis. PMID:27801353

Harnessing Electrostatic Forces to Grow Bio-inspired Hierarchical Vascular Networks

NASA Astrophysics Data System (ADS)

Behler, Kristopher; Melrose, Zachary; Schott, Andrew; Wetzel, Eric

2012-02-01

Vascular networks provide a system for fluid distribution. Artificial vascular materials with enhanced properties are currently being developed that could ultimately be integrated into systems reliant upon fluid transport while retaining their structural properties. An uninterrupted and controllable supply of liquid is optimal for many applications such as continual self-healing materials, in-situ delivery of index matched fluids, thermal management and drug delivery systems could benefit from a bio-inspired vascular approach that combines complex network geometries with minimal processing parameters. Two such approaches to induce vascular networks are electrohydrodynamic viscous fingering (EHVF) and electrical treeing (ET). EHVF is a phenomenon that occurs when a low viscosity liquid is forced through a high viscosity fluid or matrix, resulting in branches due to capillary and viscous forces in the high viscosity material. By applying voltages of 0 -- 60 kV, finger diameter is reduced. ET is the result of partial discharges in a dielectric material. In the vicinity of a small diameter electrode, the local electric field is greater than the global dielectric strength, causing a localized, step-wise, breakdown to occur forming a highly branched interconnected structure. ET is a viable method to produce networks on a smaller, micron, scale than the products of the EHVF method.

Modeling Load Dynamics to Support Resiliency-based Operations in Low-Inertia Microgrids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tuffner, Francis K.; Schneider, Kevin P.; Hansen, Jacob

Microgrids have repeatedly demonstrated the ability to provide uninterrupted service to critical end-use loads during normal outages, severe weather events, and natural disasters. While their ability to provide critical services is well documented, microgrids present a more dynamic operational environment than grid-connected distribution systems. The electrodynamics of a microgrid are commonly driven by the high inertia of rotating generators, which are common in many microgrids. In such high-inertia systems, the impact of end-use load electromechanical dynamics are often not examined. However, with the increased penetration of inverter-based generation with little or no inertia, it is necessary to consider the impactmore » that the dynamics of the end-use loads have on the operations of microgrids, particularly for a resiliency-based operation. These operations include, but are not limited to, switching operations, loss of generating units, and the starting of induction motors. This paper examines the importance of including multi-state electromechanical dynamic models of the end-use load when evaluating the operations of low inertia microgrids, and shows that by properly representing their behavior, it is possible to cost effectively size equipment while supporting resilient operations of critical end-use loads.« less

Flight Crew Factors for CTAS/FMS Integration in the Terminal Area

NASA Technical Reports Server (NTRS)

Crane, Barry W.; Prevot, Thomas; Palmer, Everett A.; Shafto, M. (Technical Monitor)

2000-01-01

Center TRACON Automation System (CTAS)/Flight Management System (FMS) integration on the flightdeck implies flight crews flying coupled in highly automated FMS modes [i.e. Vertical Navigation (VNAV) and Lateral Navigation (LNAV)] from top of descent to the final approach phase of flight. Pilots may also have to make FMS route edits and respond to datalink clearances in the Terminal Radar Approach Control (TRACON) airspace. This full mission simulator study addresses how the introduction of these FMS descent procedures affect crew activities, workload, and performance. It also assesses crew acceptance of these procedures. Results indicate that the number of crew activities and workload ratings are significantly reduced below current day levels when FMS procedures can be flown uninterrupted, but that activity numbers increase significantly above current day levels and workload ratings return to current day levels when FMS procedures are interrupted by common ATC interventions and CTAS routing advisories. Crew performance showed some problems with speed control during FMS procedures. Crew acceptance of the FMS procedures and route modification requirements was generally high; a minority of crews expressed concerns about use of VNAV in the TRACON airspace. Suggestions for future study are discussed.

Modeling Load Dynamics to Support Resiliency-based Operations in Low-Inertia Microgrids

DOE PAGES

Tuffner, Francis K.; Schneider, Kevin P.; Hansen, Jacob; ...

2018-03-07

Microgrids have repeatedly demonstrated the ability to provide uninterrupted service to critical end-use loads during normal outages, severe weather events, and natural disasters. While their ability to provide critical services is well documented, microgrids present a more dynamic operational environment than grid-connected distribution systems. The electrodynamics of a microgrid are commonly driven by the high inertia of rotating generators, which are common in many microgrids. In such high-inertia systems, the impact of end-use load electromechanical dynamics are often not examined. However, with the increased penetration of inverter-based generation with little or no inertia, it is necessary to consider the impactmore » that the dynamics of the end-use loads have on the operations of microgrids, particularly for a resiliency-based operation. These operations include, but are not limited to, switching operations, loss of generating units, and the starting of induction motors. This paper examines the importance of including multi-state electromechanical dynamic models of the end-use load when evaluating the operations of low inertia microgrids, and shows that by properly representing their behavior, it is possible to cost effectively size equipment while supporting resilient operations of critical end-use loads.« less

Chimeric peptide-mediated siRNA transduction to inhibit HIV-1 infection.

PubMed

Bivalkar-Mehla, Shalmali; Mehla, Rajeev; Chauhan, Ashok

2017-04-01

Persistent human immunodeficiency virus 1 (HIV-1) infection provokes immune activation and depletes CD4 +  lymphocytes, leading to acquired immunodeficiency syndrome. Uninterrupted administration of combination antiretroviral therapy (cART) in HIV-infected patients suppresses viral replication to below the detectable level and partially restores the immune system. However, cART-unresponsive residual HIV-1 infection and elusive transcriptionally silent but reactivatable viral reservoirs maintain a permanent viral DNA blue print. The virus rebounds within a few weeks after interruption of suppressive therapy. Adjunct gene therapy to control viral replication by ribonucleic acid interference (RNAi) is a post-transcriptional gene silencing strategy that could suppress residual HIV-1 burden and overcome viral resistance. Small interfering ribonucleic acids (siRNAs) are efficient transcriptional inhibitors, but need delivery systems to reach inside target cells. We investigated the potential of chimeric peptide (FP-PTD) to deliver specific siRNAs to HIV-1-susceptible and permissive cells. Chimeric FP-PTD peptide was designed with an RNA binding domain (PTD) to bind siRNA and a cell fusion peptide domain (FP) to enter cells. FP-PTD-siRNA complex entered and inhibited HIV-1 replication in susceptible cells, and could be a candidate for in vivo testing.

Demand thrust pumped propulsion with automatic warm gas valving

NASA Astrophysics Data System (ADS)

Whitehead, J. C.

1992-06-01

Operation of a thrust-on-demand, monopropellant rocket propulsion system which uses lightweight low-pressure tankage, free-piston pumps, and a small high-pressure thrust chamber, is explained. The pump intake-exhaust valves use warm gas pneumatic signals to ensure that two reciprocating pumps are alternately pressurized, with overlap during switchover to permit uninterrupted propellant flow. Experiments demonstrate that the miniature pumps operate at any speed depending on downstream demand, and can deliver nearly their own mass in hydrazine per second, at 7 MPa (1000 psi). The valves, which use the alternating layers of metal and graphite to mitigate the effects of differential thermal expansion, have been warm-gas tested for thousands of cycles. For biopropellant operation, a pair of reciprocating oxidizer pumps would be slaved to the fuel pumps' pneumatic oscillator, to provide for pulsed or continuous demand-driven flow of both liquids. Mass ratios and thrust-to-weight ratios of demand-thrust pumped propulsion systems compare quite favorably to those of pressure-fed and turbo-pumped systems. Due to the relatively high densities of storable propellants, liquid mass fractions greater than 0.95 are attainable with these novel pumps, with thrust/weight ratios above 10. The high performance potential of small propulsion systems which use reciprocating pumps suggests that this technology can significantly increase the capability of many types of small spacecraft.

Landsat 8 on-orbit characterization and calibration system

USGS Publications Warehouse

Micijevic, Esad; Morfitt, Ron; Choate, Michael J.

2011-01-01

The Landsat Data Continuity Mission (LDCM) is planning to launch the Landsat 8 satellite in December 2012, which continues an uninterrupted record of consistently calibrated globally acquired multispectral images of the Earth started in 1972. The satellite will carry two imaging sensors: the Operational Land Imager (OLI) and the Thermal Infrared Sensor (TIRS). The OLI will provide visible, near-infrared and short-wave infrared data in nine spectral bands while the TIRS will acquire thermal infrared data in two bands. Both sensors have a pushbroom design and consequently, each has a large number of detectors to be characterized. Image and calibration data downlinked from the satellite will be processed by the U.S. Geological Survey (USGS) Earth Resources Observation and Science (EROS) Center using the Landsat 8 Image Assessment System (IAS), a component of the Ground System. In addition to extracting statistics from all Earth images acquired, the IAS will process and trend results from analysis of special calibration acquisitions, such as solar diffuser, lunar, shutter, night, lamp and blackbody data, and preselected calibration sites. The trended data will be systematically processed and analyzed, and calibration and characterization parameters will be updated using both automatic and customized manual tools. This paper describes the analysis tools and the system developed to monitor and characterize on-orbit performance and calibrate the Landsat 8 sensors and image data products.

Aspirin desensitization in aspirin-sensitive asthma: failure to maintain a desensitized state during prolonged therapy.

PubMed

Dankner, R E; Wedner, H J

1983-11-01

A patient with a history of asthma induced by acetylsalicylic acid (ASA) was found to be ASA sensitive when orally challenged with ASA. She was successfully desensitized using incremental doses of ASA given orally and maintained on ASA or other nonsteroidal antiinflammatory (NSAI) agents for the treatment of arthritis. After 6 months of uninterrupted therapy the patient developed asthmatic symptoms that were related to ASA and NSAI drug therapy. Although desensitization may be achieved in patients with ASA-sensitive asthma, sensitivity may recur despite continuous therapy.

Fuel cycle for a fusion neutron source

NASA Astrophysics Data System (ADS)

Ananyev, S. S.; Spitsyn, A. V.; Kuteev, B. V.

2015-12-01

The concept of a tokamak-based stationary fusion neutron source (FNS) for scientific research (neutron diffraction, etc.), tests of structural materials for future fusion reactors, nuclear waste transmutation, fission reactor fuel production, and control of subcritical nuclear systems (fusion-fission hybrid reactor) is being developed in Russia. The fuel cycle system is one of the most important systems of FNS that provides circulation and reprocessing of the deuterium-tritium fuel mixture in all fusion reactor systems: the vacuum chamber, neutral injection system, cryogenic pumps, tritium purification system, separation system, storage system, and tritium-breeding blanket. The existing technologies need to be significantly upgraded since the engineering solutions adopted in the ITER project can be only partially used in the FNS (considering the capacity factor higher than 0.3, tritium flow up to 200 m3Pa/s, and temperature of reactor elements up to 650°C). The deuterium-tritium fuel cycle of the stationary FNS is considered. The TC-FNS computer code developed for estimating the tritium distribution in the systems of FNS is described. The code calculates tritium flows and inventory in tokamak systems (vacuum chamber, cryogenic pumps, neutral injection system, fuel mixture purification system, isotope separation system, tritium storage system) and takes into account tritium loss in the fuel cycle due to thermonuclear burnup and β decay. For the two facility versions considered, FNS-ST and DEMO-FNS, the amount of fuel mixture needed for uninterrupted operation of all fuel cycle systems is 0.9 and 1.4 kg, consequently, and the tritium consumption is 0.3 and 1.8 kg per year, including 35 and 55 g/yr, respectively, due to tritium decay.

Evaluation of BBL™ Sensi-Discs™ and FTA® cards as sampling devices for detection of rotavirus in stool samples

PubMed Central

Tam, Ka Ian; Esona, Mathew D.; Williams, Alice; Ndze, Valentine N.; Boula, Angeline; Bowen, Michael D.

2015-01-01

Rotavirus is the most important cause of severe childhood gastroenteritis worldwide. Rotavirus vaccines are available and rotavirus surveillance is carried out to assess vaccination impact. In surveillance studies, stool samples are stored typically at 4°C or frozen to maintain sample quality. Uninterrupted cold storage is a problem in developing countries because of power interruptions. Cold-chain transportation of samples from collection sites to testing laboratories is costly. In this study, we evaluated the use of BBL™ Sensi-Discs™ and FTA® cards for storage and transportation of samples for virus isolation, EIA, and RT-PCR testing. Infectious rotavirus was recovered after 30 days of storage on Sensi-Discs™ at room temperature. We were able to genotype 98–99% of samples stored on Sensi-Discs™ and FTA® cards at temperatures ranging from −80°C to 37°C up to 180 days. A field sampling test using samples prepared and shipped from Cameroon, showed that both matrices yielded 100% genotyping success compared with whole stool and Sensi-Discs™ demonstrated 95% concordance with whole stool in EIA testing. The utilization of BBL™ Sensi-Discs™ and FTA® cards for stool sample storage and shipment has the potential to have great impact on global public health by facilitating surveillance and epidemiological investigations of rotavirus strains worldwide at a reduced cost. PMID:26022083

Perceived Health Locus of Control, Self-Esteem, and Its Relations to Psychological Well-Being Status in Iranian Students

PubMed Central

Moshki, M; Ashtarian, H

2010-01-01

Background: Health locus of control (HLC) has been associated with a variety of ailments and health outcomes and designed to predict behaviors and cognitive processes relevant to mental and physical health. This study investigated the relationships between perceived health locus of control, self-esteem, and mental health status among Iranian students. Methods: In this analytical study the subjects were recruited from students in Gonabad University of Medical Sciences, Iran, who studied in the first year (N=154). Students completed the questionnaires for assessing demographic, perceived health locus of control, self - esteem and psychological well- being data. Results: The statistical analysis revealed a negative relationship between perceived Internal HLC and self-esteem with psychological well-being. The positive correlation of the perceived Chance HLC with psychological well-being was statistically significant (r= 0.21, P< 0.01) and the positive correlation of the perceived Internal HLC with self-esteem was statistically significant (r= 0.25, P< 0.01). A significantly direct relationship between low perceived Internal HLC, self–esteem and psychological problems was found among these students. Conclusion: The findings will be addressed in relation to their implications for effective mental health education based on health locus of control especially internal and powerful others beliefs associated with self-esteem for students. This will require additional monitoring and uninterrupted trying in order to be effective. PMID:23113040

Uninterrupted monitoring of drug effects in human-induced pluripotent stem cell-derived cardiomyocytes with bioluminescence Ca2+ microscopy.

PubMed

Suzuki, Kazushi; Onishi, Takahito; Nakada, Chieko; Takei, Shunsuke; Daniels, Matthew J; Nakano, Masahiro; Matsuda, Tomoki; Nagai, Takeharu

2018-05-18

Cardiomyocytes derived from human-induced pluripotent stem cells are a powerful platform for high-throughput drug screening in vitro. However, current modalities for drug testing, such as electrophysiology and fluorescence imaging have inherent drawbacks. To circumvent these problems, we report the development of a bioluminescent Ca 2+ indicator GmNL(Ca 2+ ), and its application in a customized microscope for high-throughput drug screening. GmNL(Ca 2+ ) gives a 140% signal change with Ca 2+ , and can image drug-induced changes of Ca 2+ dynamics in cultured cells. Since bioluminescence requires application of a chemical substrate, which is consumed over ~ 30 min we made a dedicated microscope with automated drug dispensing inside a light-tight box, to control drug addition. To overcome thermal instability of the luminescent substrate, or small molecule, dual climate control enables distinct temperature settings in the drug reservoir and the biological sample. By combining GmNL(Ca 2+ ) with this adaptation, we could image spontaneous Ca 2+ transients in cultured cardiomyocytes and phenotype their response to well-known drugs without accessing the sample directly. In addition, the bioluminescent strategy demonstrates minimal perturbation of contractile parameters and long-term observation attributable to lack of phototoxicity and photobleaching. Overall, bioluminescence may enable more accurate drug screening in a high-throughput manner.

Planck 2015 results: V. LFI calibration

DOE PAGES

Ade, P. A. R.; Aghanim, N.; Ashdown, M.; ...

2016-09-20

In this paper, we present a description of the pipeline used to calibrate the Planck Low Frequency Instrument (LFI) timelines into thermodynamic temperatures for the Planck 2015 data release, covering four years of uninterrupted operations. As in the 2013 data release, our calibrator is provided by the spin-synchronous modulation of the cosmic microwave background dipole, but we now use the orbital component, rather than adopting the Wilkinson Microwave Anisotropy Probe (WMAP) solar dipole. This allows our 2015 LFI analysis to provide an independent Solar dipole estimate, which is in excellent agreement with that of HFI and within 1σ (0.3% inmore » amplitude) of the WMAP value. This 0.3% shift in the peak-to-peak dipole temperature from WMAP and a general overhaul of the iterative calibration code increases the overall level of the LFI maps by 0.45% (30 GHz), 0.64% (44 GHz), and 0.82% (70 GHz) in temperature with respect to the 2013 Planck data release, thus reducing the discrepancy with the power spectrum measured by WMAP. We estimate that the LFI calibration uncertainty is now at the level of 0.20% for the 70 GHz map, 0.26% for the 44 GHz map, and 0.35% for the 30 GHz map. Finally, we provide a detailed description of the impact of all the changes implemented in the calibration since the previous data release.« less

Planck 2015 results: V. LFI calibration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ade, P. A. R.; Aghanim, N.; Ashdown, M.

In this paper, we present a description of the pipeline used to calibrate the Planck Low Frequency Instrument (LFI) timelines into thermodynamic temperatures for the Planck 2015 data release, covering four years of uninterrupted operations. As in the 2013 data release, our calibrator is provided by the spin-synchronous modulation of the cosmic microwave background dipole, but we now use the orbital component, rather than adopting the Wilkinson Microwave Anisotropy Probe (WMAP) solar dipole. This allows our 2015 LFI analysis to provide an independent Solar dipole estimate, which is in excellent agreement with that of HFI and within 1σ (0.3% inmore » amplitude) of the WMAP value. This 0.3% shift in the peak-to-peak dipole temperature from WMAP and a general overhaul of the iterative calibration code increases the overall level of the LFI maps by 0.45% (30 GHz), 0.64% (44 GHz), and 0.82% (70 GHz) in temperature with respect to the 2013 Planck data release, thus reducing the discrepancy with the power spectrum measured by WMAP. We estimate that the LFI calibration uncertainty is now at the level of 0.20% for the 70 GHz map, 0.26% for the 44 GHz map, and 0.35% for the 30 GHz map. Finally, we provide a detailed description of the impact of all the changes implemented in the calibration since the previous data release.« less

Evaluation of BBL™ Sensi-Discs™ and FTA® cards as sampling devices for detection of rotavirus in stool samples.

PubMed

Tam, Ka Ian; Esona, Mathew D; Williams, Alice; Ndze, Valantine N; Boula, Angeline; Bowen, Michael D

2015-09-15

Rotavirus is the most important cause of severe childhood gastroenteritis worldwide. Rotavirus vaccines are available and rotavirus surveillance is carried out to assess vaccination impact. In surveillance studies, stool samples are stored typically at 4°C or frozen to maintain sample quality. Uninterrupted cold storage is a problem in developing countries because of power interruptions. Cold-chain transportation of samples from collection sites to testing laboratories is costly. In this study, we evaluated the use of BBL™ Sensi-Discs™ and FTA(®) cards for storage and transportation of samples for virus isolation, EIA, and RT-PCR testing. Infectious rotavirus was recovered after 30 days of storage on Sensi-Discs™ at room temperature. We were able to genotype 98-99% of samples stored on Sensi-Discs™ and FTA(®) cards at temperatures ranging from -80°C to 37°C up to 180 days. A field sampling test using samples prepared and shipped from Cameroon, showed that both matrices yielded 100% genotyping success compared with whole stool and Sensi-Discs™ demonstrated 95% concordance with whole stool in EIA testing. The utilization of BBL™ Sensi-Discs™ and FTA(®) cards for stool sample storage and shipment has the potential to have great impact on global public health by facilitating surveillance and epidemiological investigations of rotavirus strains worldwide at a reduced cost. Published by Elsevier B.V.

Kagome fiber based ultrafast laser microsurgery probe delivering micro-Joule pulse energies.

PubMed

Subramanian, Kaushik; Gabay, Ilan; Ferhanoğlu, Onur; Shadfan, Adam; Pawlowski, Michal; Wang, Ye; Tkaczyk, Tomasz; Ben-Yakar, Adela

2016-11-01

We present the development of a 5 mm, piezo-actuated, ultrafast laser scalpel for fast tissue microsurgery. Delivery of micro-Joules level energies to the tissue was made possible by a large, 31 μm, air-cored inhibited-coupling Kagome fiber. We overcome the fiber's low NA by using lenses made of high refractive index ZnS, which produced an optimal focusing condition with 0.23 NA objective. The optical design achieved a focused laser spot size of 4.5 μm diameter covering a 75 × 75 μm 2 scan area in a miniaturized setting. The probe could deliver the maximum available laser power, achieving an average fluence of 7.8 J/cm 2 on the tissue surface at 62% transmission efficiency. Such fluences could produce uninterrupted, 40 μm deep cuts at translational speeds of up to 5 mm/s along the tissue. We predicted that the best combination of speed and coverage exists at 8 mm/s for our conditions. The onset of nonlinear absorption in ZnS, however, limited the probe's energy delivery capabilities to 1.4 μJ for linear operation at 1.5 picosecond pulse-widths of our fiber laser. Alternatives like broadband CaF 2 crystals should mitigate such nonlinear limiting behavior. Improved opto-mechanical design and appropriate material selection should allow substantially higher fluence delivery and propel such Kagome fiber-based scalpels towards clinical translation.

Planck 2015 results. V. LFI calibration

NASA Astrophysics Data System (ADS)

Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Banday, A. J.; Barreiro, R. B.; Bartolo, N.; Battaglia, P.; Battaner, E.; Benabed, K.; Benoît, A.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bock, J. J.; Bonaldi, A.; Bonavera, L.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Bucher, M.; Burigana, C.; Butler, R. C.; Calabrese, E.; Cardoso, J.-F.; Catalano, A.; Chamballu, A.; Christensen, P. R.; Colombi, S.; Colombo, L. P. L.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Dickinson, C.; Diego, J. M.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Enßlin, T. A.; Eriksen, H. K.; Fergusson, J.; Finelli, F.; Forni, O.; Frailis, M.; Franceschi, E.; Frejsel, A.; Galeotta, S.; Galli, S.; Ganga, K.; Giard, M.; Giraud-Héraud, Y.; Gjerløw, E.; González-Nuevo, J.; Górski, K. M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Hansen, F. K.; Hanson, D.; Harrison, D. L.; Henrot-Versillé, S.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hornstrup, A.; Hovest, W.; Huffenberger, K. M.; Hurier, G.; Jaffe, A. H.; Jaffe, T. R.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kisner, T. S.; Knoche, J.; Krachmalnicoff, N.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lähteenmäki, A.; Lamarre, J.-M.; Lasenby, A.; Lattanzi, M.; Lawrence, C. R.; Leahy, J. P.; Leonardi, R.; Lesgourgues, J.; Levrier, F.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; Maggio, G.; Maino, D.; Mandolesi, N.; Mangilli, A.; Maris, M.; Martin, P. G.; Martínez-González, E.; Masi, S.; Matarrese, S.; McGehee, P.; Meinhold, P. R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Montier, L.; Morgante, G.; Mortlock, D.; Moss, A.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C. B.; Nørgaard-Nielsen, H. U.; Novikov, D.; Novikov, I.; Paci, F.; Pagano, L.; Pajot, F.; Paoletti, D.; Partridge, B.; Pasian, F.; Patanchon, G.; Pearson, T. J.; Peel, M.; Perdereau, O.; Perotto, L.; Perrotta, F.; Pettorino, V.; Piacentini, F.; Pierpaoli, E.; Pietrobon, D.; Pointecouteau, E.; Polenta, G.; Pratt, G. W.; Prézeau, G.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renzi, A.; Rocha, G.; Romelli, E.; Rosset, C.; Rossetti, M.; Roudier, G.; Rubiño-Martín, J. A.; Rusholme, B.; Sandri, M.; Santos, D.; Savelainen, M.; Scott, D.; Seiffert, M. D.; Shellard, E. P. S.; Spencer, L. D.; Stolyarov, V.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Tavagnacco, D.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Tuovinen, J.; Türler, M.; Umana, G.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vassallo, T.; Vielva, P.; Villa, F.; Wade, L. A.; Wandelt, B. D.; Watson, R.; Wehus, I. K.; Wilkinson, A.; Yvon, D.; Zacchei, A.; Zonca, A.

2016-09-01

We present a description of the pipeline used to calibrate the Planck Low Frequency Instrument (LFI) timelines into thermodynamic temperatures for the Planck 2015 data release, covering four years of uninterrupted operations. As in the 2013 data release, our calibrator is provided by the spin-synchronous modulation of the cosmic microwave background dipole, but we now use the orbital component, rather than adopting the Wilkinson Microwave Anisotropy Probe (WMAP) solar dipole. This allows our 2015 LFI analysis to provide an independent Solar dipole estimate, which is in excellent agreement with that of HFI and within 1σ (0.3% in amplitude) of the WMAP value. This 0.3% shift in the peak-to-peak dipole temperature from WMAP and a general overhaul of the iterative calibration code increases the overall level of the LFI maps by 0.45% (30 GHz), 0.64% (44 GHz), and 0.82% (70 GHz) in temperature with respect to the 2013 Planck data release, thus reducing the discrepancy with the power spectrum measured by WMAP. We estimate that the LFI calibration uncertainty is now at the level of 0.20% for the 70 GHz map, 0.26% for the 44 GHz map, and 0.35% for the 30 GHz map. We provide a detailed description of the impact of all the changes implemented in the calibration since the previous data release.

A Mobile App for Geochemical Field Data Acquisition

NASA Astrophysics Data System (ADS)

Klump, J. F.; Reid, N.; Ballsun-Stanton, B.; White, A.; Sobotkova, A.

2015-12-01

We have developed a geochemical sampling application for use on Android tablets. This app was developed together with the Federated Archaeological Information Management Systems (FAIMS) at Macquarie University and is based on the open source FAIMS mobile platform, which was originally designed for archaeological field data collection. The FAIMS mobile platform has proved valuable for hydrogeochemical, biogeochemical, soil and rock sample collection due to the ability to customise data collection methodologies for any field research. The module we commissioned allows for using inbuilt or external GPS to locate sample points, it incorporates standard and incremental sampling names which can be easily fed into the International Geo-Sample Number (IGSN). Sampling can be documented not only in metadata, but also accompanied by photographic documentation and sketches. The module is augmented by dropdown menus for fields specific for each sample type and user defined tags. The module also provides users with an overview of all records from a field campaign in a records viewer. We also use basic mapping functionality, showing the current location, sampled points overlaid on preloaded rasters, and allows for drawing of points and simple polygons to be later exported as shape files. A particular challenge is the remoteness of the sampling locations, hundreds of kilometres away from network access. The first trial raised the issue of backup without access to the internet, so in collaboration with the FAIMS team and Solutions First, we commissioned a vehicle mounted portable server. This server box is constantly syncing with the tablets in the field via Wi-Fi, it has an uninterruptible power supply that can run for up to 45 minutes when the vehicle is turned off, and a 1TB hard drive for storage of all data and photographs. The server can be logged into via any of the field tablets or laptop to download all the data collected to date or to just view it on the server.

THROUGH THE LOOKING GLASS: HST SPECTROSCOPY OF FAINT GALAXIES LENSED BY THE FRONTIER FIELDS CLUSTER MACSJ0717.5+3745

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schmidt, K. B.; Treu, T.; Wang, X.

The Grism Lens-Amplified Survey from Space (GLASS) is a Hubble Space Telescope (HST) Large Program, which will obtain 140 orbits of grism spectroscopy of the core and infall regions of 10 galaxy clusters, selected to be among the very best cosmic telescopes. Extensive HST imaging is available from many sources including the CLASH and Frontier Fields programs. We introduce the survey by analyzing spectra of faint multiply-imaged galaxies and z ≳ 6 galaxy candidates obtained from the first 7 orbits out of 14 targeting the core of the Frontier Fields cluster MACSJ0717.5+3745. Using the G102 and G141 grisms to covermore » the wavelength range 0.8-1.7 μm, we confirm four strongly lensed systems by detecting emission lines in each of the images. For the 9 z ≳ 6 galaxy candidates clear from contamination, we do not detect any emission lines down to a 7 orbit 1σ noise level of ∼5 × 10{sup –18} erg s{sup –1} cm{sup –2}. Taking lensing magnification into account, our flux sensitivity reaches ∼0.2-5 × 10{sup –18} erg s{sup –1}cm{sup –2}. These limits over an uninterrupted wavelength range rule out the possibility that the high-z galaxy candidates are instead strong line emitters at lower redshift. These results show that by means of careful modeling of the background—and with the assistance of lensing magnification—interesting flux limits can be reached for large numbers of objects, avoiding pre-selection and the wavelength restrictions inherent to ground-based multi-slit spectroscopy. These observations confirm the power of slitless HST spectroscopy even in fields as crowded as a cluster core.« less

Contraceptive security, information flow, and local adaptations: family planning Morocco.

PubMed

Chandani, Y; Breton, G

2001-12-01

Many developing countries increasingly recognize and acknowledge family planning as a critical part of socio-economic development. However, with few health dollars to go around, countries tend to provide essential drugs for curative care, rather than for family planning products. Donors have historically provided free contraceptives for family planning services. Whether products are donated or purchased by the country, a successful family planning program depends on an uninterrupted supply of products, beginning with the manufacturer and ending with the customer. Any break in the supply chain may cause a family planning program to fail. A well-functioning logistics system can manage the supply chain and ensure that the customers have the products they need, when they need them. Morocco was selected for the case study. The researchers had ready access to key informants and information about the Logistics Management Information System. Because the study had time and resource constraints, research included desktop reviews and interview, rather than data collection in the field. The case study showed that even in a challenging environment an LMIS can be successfully deployed and fully supported by the users. It is critical to customize the system to a country-specific situation to ensure buy-in for the implementation. Significant external support funding and technical expertise are critical components to ensure the initial success of the system. Nonetheless, evidence from the case study shows that, after a system has been implemented, the benefits may not ensure its institutionalization. Other support, including local funding and technical expertise, is required.

Validity of police contacts as a performance indicator for the public mental health care system in Amsterdam: an open cohort study.

PubMed

Lauriks, S; Buster, M C A; de Wit, M A S; Arah, O A; Hoogendoorn, A W; Peen, J; Klazinga, N S

2018-06-01

The Public Mental Health Care (PMHC) system is a network of public services and care- and support institutions financed from public funds. Performance indicators based on the registration of police contacts could be a reliable and useful source of information for the stakeholders of the PMHC system to monitor performance. This study aimed to provide evidence on the validity of using police contacts as a performance indicator to assess the continuity of care in the PMHC system. Data on services received, police contacts and detention periods of 1928 people that entered the PMHC system in the city of Amsterdam were collected over a period of 51 months. Continuity of care was defined as receiving more than 90 days of uninterrupted service. The associations between police contacts and continuity were analyzed with multilevel Poisson and multivariate linear regression modeling. Clients had on average 2.12 police contacts per person-year. Clients with police contacts were younger, more often single, male, and more often diagnosed with psychiatric or substance abuse disorders than clients without police contacts. Incidence rates of police contacts were significantly lower for clients receiving continuous care than for clients receiving discontinuous care. The number of police contacts of clients receiving PMHC coordination per month was found to be a significant predictor of the percentage of clients in continuous care. The number of police contacts of clients can be used as a performance indicator for an urban PMHC system to evaluate the continuity of care in the PMHC system.

Unimpaired Autoreactive T-Cell Traffic Within the Central Nervous System During Tumor Necrosis Factor Receptor-Mediated inhibition of Experimental Autoimmune Encephalomyelitis

NASA Astrophysics Data System (ADS)

Korner, Heinrich; Goodsall, Anna L.; Lemckert, Frances A.; Scallon, Bernard J.; Ghrayeb, John; Ford, Andrew L.; Sedgwick, Jonathon D.

1995-11-01

The critical role of tumor necrosis factor (TNF) as a mediator in autoimmune inflammatory processes is evident from in vivo studies with TNF-blocking agents. However, the mechanisms by which TNF, and possibly also its homologue lymphotoxin α, contributes to development of pathology in rheumatoid arthritis and Crohn disease and in animal models like experimental autoimmune encephalomyelitis is unclear. Possibilities include regulation of vascular adhesion molecules enabling leukocyte movement into tissues or direct cytokine-mediated effector functions such as mediation of tissue damage. Here we show that administration of a TNF receptor (55 kDa)-IgG fusion protein prevented clinical signs of actively induced experimental autoimmune encephalomyelitis. Significantly, the total number of CD4^+ T lymphocytes isolated from the central nervous system of clinically healthy treated versus diseased control animals was comparable. By using a CD45 congenic model of passively transferred experimental autoimmune encephalomyelitis to enable tracking of myelin basic protein-specific effector T lymphocytes, prevention of clinical signs of disease was again demonstrated in treated animals but without quantitative or qualitative impediment to the movement of autoreactive T lymphocytes to and within the central nervous system. Thus, despite the uninterrupted movement of specific T lymphocytes into the target tissue, subsequent disease development was blocked. This provides compelling evidence for a direct effector role of TNF/lymphotoxin α in autoimmune tissue damage.

Bed occupancy monitoring: data processing and clinician user interface design.

PubMed

Pouliot, Melanie; Joshi, Vilas; Goubran, Rafik; Knoefel, Frank

2012-01-01

Unobtrusive and continuous monitoring of patients, especially at their place of residence, is becoming a significant part of the healthcare model. A variety of sensors are being used to monitor different patient conditions. Bed occupancy monitoring provides clinicians a quantitative measure of bed entry/exit patterns and may provide information relating to sleep quality. This paper presents a bed occupancy monitoring system using a bed pressure mat sensor. A clinical trial was performed involving 8 patients to collect bed occupancy data. The trial period for each patient ranged from 5-10 weeks. This data was analyzed using a participatory design methodology incorporating clinician feedback to obtain bed occupancy parameters. The parameters extracted include the number of bed exits per night, the bed exit weekly average (including minimum and maximum), the time of day of a particular exit, and the amount of uninterrupted bed occupancy per night. The design of a clinical user interface plays a significant role in the acceptance of such patient monitoring systems by clinicians. The clinician user interface proposed in this paper was designed to be intuitive, easy to navigate and not cause information overload. An iterative design methodology was used for the interface design. The interface design is extendible to incorporate data from multiple sensors. This allows the interface to be part of a comprehensive remote patient monitoring system.

Loaded Transducer Fpr Downhole Drilling Component

DOEpatents

Hall, David R.; Hall, H. Tracy; Pixton, David; Dahlgren, Scott; Sneddon, Cameron; Briscoe, Michael; Fox, Joe

2005-07-05

A robust transmission element for transmitting information between downhole tools, such as sections of drill pipe, in the presence of hostile environmental conditions, such as heat, dirt, rocks, mud, fluids, lubricants, and the like. The transmission element maintains reliable connectivity between transmission elements, thereby providing an uninterrupted flow of information between drill string components. A transmission element is mounted within a recess proximate a mating surface of a downhole drilling component, such as a section of drill pipe. To close gaps present between transmission elements, transmission elements may be biased with a "spring force," urging them closer together.

Loaded transducer for downhole drilling components

DOEpatents

Hall, David R.; Hall, Jr., H. Tracy; Pixton, David S.; Briscoe, Michael A.; Dahlgren, Scott Steven; Fox, Joe; Sneddon, Cameron

2006-02-21

A robust transmission element for transmitting information between downhole tools, such as sections of drill pipe, in the presence of hostile environmental conditions, such as heat, dirt, rocks, mud, fluids, lubricants, and the like. The transmission element maintains reliable connectivity between transmission elements, thereby providing an uninterrupted flow of information between drill string components. A transmission element is mounted within a recess proximate a mating surface of a downhole drilling component, such as a section of drill pipe. To close gaps present between transmission elements, transmission elements may be biased with a "spring force, urging them closer together."

Does Prison-Based Adult Basic Education Improve Postrelease Outcomes for Male Prisoners in Florida?

PubMed Central

Cho, Rosa Minhyo; Tyler, John H.

2014-01-01

The authors use administrative data from Florida to determine the extent to which prison-based adult basic education (ABE) improves inmate’s postrelease labor market outcomes, such as earnings and employment. Using two nonexperimental comparison groups, the authors find evidence that ABE participation is associated with higher postrelease earnings and employment rates, especially for minorities. The authors find that the relationship is the largest for ABE participants who had uninterrupted ABE instruction and for those who received other education services. However, the results do not find any positive effects of ABE participation on reducing recidivism. PMID:25580020

Biogasification of sorghum

DOE Office of Scientific and Technical Information (OSTI.GOV)

Biljetina, R.; Srivastava, V.J.; Isaacson, H.R.

1987-01-01

The Institute of Gas Technology has been operating a 1200-gallon, anaerobic solids-concentrating digester at the Walt Disney World Resort Complex in Lake Buena Vista, Florida. This digester development work is part of a larger effort sponsored by the Gas Research Institute to provide an effective community waste treatment and energy recovery concept for smaller communities. As a result, an economically attractive, water hyacinth-based wastewater treatment system was developed that includes the digestion of water hyacinth and sludge to methane. A further extension of the community waste treatment concept is to include agricultural wastes in the energy recovery scheme. Therefore, duringmore » 1986 a test program was initiated to obtain data on the digestion of sorghum in the solids concentrating digester. Performance data was collected at both mesophilic and thermophilic operating conditions at total organic loading rates of 0.25 and 0.5 pounds per cubic foot of digester volume per day, respectively. Excellent methane yields were obtained during twelve months of stable and uninterrupted operation. This paper summarizes the performance data obtained on sorghum in this digester. 7 refs., 6 figs., 6 tabs.« less

Fidelity Witnesses for Fermionic Quantum Simulations

NASA Astrophysics Data System (ADS)

Gluza, M.; Kliesch, M.; Eisert, J.; Aolita, L.

2018-05-01

The experimental interest and developments in quantum spin-1 /2 chains has increased uninterruptedly over the past decade. In many instances, the target quantum simulation belongs to the broader class of noninteracting fermionic models, constituting an important benchmark. In spite of this class being analytically efficiently tractable, no direct certification tool has yet been reported for it. In fact, in experiments, certification has almost exclusively relied on notions of quantum state tomography scaling very unfavorably with the system size. Here, we develop experimentally friendly fidelity witnesses for all pure fermionic Gaussian target states. Their expectation value yields a tight lower bound to the fidelity and can be measured efficiently. We derive witnesses in full generality in the Majorana-fermion representation and apply them to experimentally relevant spin-1 /2 chains. Among others, we show how to efficiently certify strongly out-of-equilibrium dynamics in critical Ising chains. At the heart of the measurement scheme is a variant of importance sampling specially tailored to overlaps between covariance matrices. The method is shown to be robust against finite experimental-state infidelities.

GOCE: Mission Overview and Early Results (Invited)

NASA Astrophysics Data System (ADS)

Rummel, R. F.; Muzi, D.; Drinkwater, M. R.; Floberghagen, R.; Fehringer, M.

2009-12-01

The Gravity field and steady-state Ocean Circulation Explorer (GOCE) mission is the first Earth Explorer Core mission of the Living Planet Programme of the European Space Agency (ESA). The primary objective of the GOCE mission is to provide global and regional models of the Earth gravity field and the geoid, its reference equi-potential surface, with unprecedented spatial resolution and accuracy. GOCE was launched successfully on 17 March 2009 from the Plesetsk Cosmodrome in northern Russia onboard a Rockot launch vehicle. System commissioning and payload calibration have been completed and the satellite is decaying to its initial measurement operating altitude of 255 km, which is expected to be reached in mid-September 2009. After one week of final payload calibration, GOCE will enter its first 6 month duration phase of uninterrupted science measurements at that altitude. This presentation will recall GOCE's main goals and its major development milestones. In addition, a description of the data products generated and some highlights of the satellite performance will be outlined. Artist's impression of GOCE Satellite in flight (courtesy AOES-Medialab).

Peer-reviewed public health journals from Arabic-speaking countries: An updated snapshot.

PubMed

Aboul-Enein, Basil H; Bernstein, Joshua; Bowser, Jacquelyn E

2017-02-01

There is a positive association between availability of regional peer-reviewed public health information systems and progressive change in community and population health. The objective of this brief report was to identify public health journals in Arabic-speaking countries actively publishing as of 2016. We conducted an electronic search in several electronic database records for public health journals using a combination of search terms. We excluded journals that focused on human medicine, veterinary medicine, nursing, and other discipline-specific or clinical health professions. We identified twenty-five public health journals for review. Five journals were interrupted or discontinued. Only three journals had a consistent, uninterrupted active publication history of greater than 20 years. Most journals were not in the regional native language. Introduction of regional public health-dedicated journals with in-print and electronic availability and also to be published in region-native languages may require interdisciplinary partnerships. Region-wide public health journals such as the Eastern Mediterranean Health Journal could serve as an ideal model for the establishment of additional local and regional public health journals in Arabic-speaking countries.

Starting-Up the Irbene 16-m Fully Steerable Parabolic Antenna for Radioastronomic Observations

NASA Astrophysics Data System (ADS)

Bezrukov, V.; Berzinsh, A.; Gaigals, G.; Lesinsh, A.; Trokshs, J.

2011-01-01

The methodology proposed in the paper is based on the concept of Energy Efficiency Uninterrupted Development Cycle (EEUDC). The goal of the authors was to clarify how the district heating system (DHS) development is affected by the heat consumption. The primary emphasis was given to the hot water consumption, with its noticeable daily fluctuations as well as changes caused by those in the inhabitants' way of life. The methodology, which is in good agreement with the ideology of advanced management of DHS development, employs the ISO 14000 series of standards (widely applied in the sphere of environment management). In the work, experimental results are presented that have been obtained through monitoring the hot water consumption. The results evidence that this consumption and its usage indices correspond to the level achieved by Western (in particular, North-European) countries. This circumstance changes considerably the input data for calculation of DHS elements, making it possible to work out appropriate measures in order to improve the DHS efficiency through step-by-step replacement of the elements with high energy loss.

Organizational resilience: Nonprofit organizations' response to change.

PubMed

Witmer, Hope; Mellinger, Marcela Sarmiento

2016-05-24

Organizational resilience refers to the ability to respond productively to significant disruptive change and transform challenges into opportunities. There is a gap in the literature about resilient nonprofit organizations and its application for identifying organizational conditions for successful adaption to external variables that threaten their existence. The aim of this study was to identify organizational characteristics that point to the resilience of nonprofit behavioral healthcare organizations as they successfully adapt to funding changes. A multiple case study of two behavioral health nonprofit organizations was conducted. Data was collected through interviews and focus groups, and analyzed through a qualitative content analysis. Using the framework of resilience, six themes that equipped these organizations to successfully adapt to funding changes were identified. They included: commitment to the mission, improvisation, community reciprocity, servant and transformational leadership, hope and optimism, and fiscal transparency. The findings suggest that incorporating these qualities into an organizational system equips it to systematically adapt to funding changes and other disruptive challenges. Using resilience as a process and not simply an outcome after recovery, nonprofit organizations can have the capacity to continuously respond to challenges and provide uninterrupted and valuable services to society.

Distribution and Availability of Essential Tuberculosis Diagnostic Items in Amhara Region, Ethiopia.

PubMed

Sinishaw, Mulusew Alemneh; Gebregergs, Gebremedhin Berhe; Shiferaw, Melashu Balew

2015-01-01

Adequate supplies of tuberculosis laboratory reagents and consumables are necessary for tuberculosis diagnosis and monitoring of treatment response. This study assessed the distribution and stock levels of laboratory commodities used in tuberculosis control in health centers of Amhara region, Ethiopia. A cross-sectional study was conducted in 82 health centers, among 801, providing sputum microscopy services. Stock levels were calculated, and distribution of reagents and consumables assessed. Thirty three (40.2%) health centers were under stocked for at least one of the key items for tuberculosis diagnosis at the time of visit. Fifteen (18.3%) health centers had no stocks of at least one of the key items (methylene blue (11%), carbol fuchsin (11%), acid alcohol (8.5%) and sputum cups (3.7%)). Of the 82 health centers, 77 (93.9%) did not fulfill the criteria for effective distribution of tuberculosis laboratory reagents and consumables. There were many health centers that had no or only low stocks of key tuberculosis laboratory reagents and consumables as a result of ineffective distribution system. It is necessary to strengthen supply chain management to ensure uninterrupted TB diagnostic service.

Distribution and Availability of Essential Tuberculosis Diagnostic Items in Amhara Region, Ethiopia

PubMed Central

2015-01-01

Adequate supplies of tuberculosis laboratory reagents and consumables are necessary for tuberculosis diagnosis and monitoring of treatment response. This study assessed the distribution and stock levels of laboratory commodities used in tuberculosis control in health centers of Amhara region, Ethiopia. A cross-sectional study was conducted in 82 health centers, among 801, providing sputum microscopy services. Stock levels were calculated, and distribution of reagents and consumables assessed. Thirty three (40.2%) health centers were under stocked for at least one of the key items for tuberculosis diagnosis at the time of visit. Fifteen (18.3%) health centers had no stocks of at least one of the key items (methylene blue (11%), carbol fuchsin (11%), acid alcohol (8.5%) and sputum cups (3.7%)). Of the 82 health centers, 77 (93.9%) did not fulfill the criteria for effective distribution of tuberculosis laboratory reagents and consumables. There were many health centers that had no or only low stocks of key tuberculosis laboratory reagents and consumables as a result of ineffective distribution system. It is necessary to strengthen supply chain management to ensure uninterrupted TB diagnostic service. PMID:26641097

Ensuring uninterrupted supplies of antiretroviral drugs in resource-poor settings: an example from Malawi.

PubMed

Harries, Anthony D; Schouten, Erik J; Makombe, Simon D; Libamba, Edwin; Neufville, Henry N; Some, Eliab; Kadewere, Godfrey; Lungu, Douglas

2007-02-01

Drug procurement and distribution practices are weak in many resource-poor countries, and are a major reason for lack of access to medicines. With many countries scaling up antiretroviral therapy (ART), it is vital to avoid interrupted drug supplies, which would lead to drug resistance and treatment failure. Malawi has adapted a model, based on that adopted by the country's Tuberculosis Control Programme, to allow rational ART drug forecasting. The model includes a focus on one standardized first-line ART regimen; a "push system" and "ceilings" for first-line ART drugs for facilities; use of starter pack and continuation pack kits; quarterly monitoring of patient outcomes and ART drug stocks at facility level; provision of a three-month buffer stock of ART drugs at facility level; and use of a procurement and distribution system outside central medical stores. The focus on a single first-line regimen, "ceilings" for first-line ART drugs and quarterly data collections to calculate drug needs (for new and follow-up patients, respectively), as well as the use of an independent procurement facility, allow drug orders to be made 6-9 months ahead. These measures have so far ensured that there have been no ART drug stock-outs in the country.

Experimental results from the VENUS-F critical reference state for the GUINEVERE accelerator driven system project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uyttenhove, W.; Baeten, P.; Ban, G.

The GUINEVERE (Generation of Uninterrupted Intense Neutron pulses at the lead Venus Reactor) project was launched in 2006 within the framework of FP6 EUROTRANS in order to validate on-line reactivity monitoring and subcriticality level determination in Accelerator Driven Systems. Therefore the VENUS reactor at SCK.CEN in Mol (Belgium) was modified towards a fast core (VENUS-F) and coupled to the GENEPI-3C accelerator built by CNRS The accelerator can operate in both continuous and pulsed mode. The VENUS-F core is loaded with enriched Uranium and reflected with solid lead. A well-chosen critical reference state is indispensable for the validation of the on-linemore » subcriticality monitoring methodology. Moreover a benchmarking tool is required for nuclear data research and code validation. In this paper the design and the importance of the critical reference state for the GUINEVERE project are motivated. The results of the first experimental phase on the critical core are presented. The control rods worth is determined by the rod drop technique and the application of the Modified Source Multiplication (MSM) method allows the determination of the worth of the safety rods. The results are implemented in the VENUS-F core certificate for full exploitation of the critical core. (authors)« less

Experimental results from the VENUS-F critical reference state for the GUINEVERE accelerator driven system project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uyttenhove, W.; Baeten, P.; Kochetkov, A.

The GUINEVERE (Generation of Uninterrupted Intense Neutron pulses at the lead Venus Reactor) project was launched in 2006 within the framework of FP6 EUROTRANS in order to validate online reactivity monitoring and subcriticality level determination in accelerator driven systems (ADS). Therefore, the VENUS reactor at SCK.CEN in Mol, Belgium, was modified towards a fast core (VENUS-F) and coupled to the GENEPI-3C accelerator built by CNRS. The accelerator can operate in both continuous and pulsed mode. The VENUS-F core is loaded with enriched Uranium and reflected with solid lead. A well-chosen critical reference state is indispensable for the validation of themore » online subcriticality monitoring methodology. Moreover, a benchmarking tool is required for nuclear data research and code validation. In this paper, the design and the importance of the critical reference state for the GUINEVERE project are motivated. The results of the first experimental phase on the critical core are presented. The control rods worth is determined by the positive period method and the application of the Modified Source Multiplication (MSM) method allows the determination of the worth of the safety rods. The results are implemented in the VENUS-F core certificate for full exploitation of the critical core. (authors)« less

An assessment of the barriers to accessing the Basic Package of Health Services (BPHS) in Afghanistan: was the BPHS a success?

PubMed

Frost, Alexandra; Wilkinson, Matthew; Boyle, Peter; Patel, Preeti; Sullivan, Richard

2016-11-15

Afghanistan is one of the most fragile and conflict-affected countries in the world. It has experienced almost uninterrupted conflict for the last thirty years, with the present conflict now lasting over a decade. With no history of a functioning healthcare system, the creation of the Basic Package of Health Services (BPHS) in 2003 was a response to Afghanistan's dire health needs following decades of war. Its objective was to provide a bare minimum of essential health services, which could be scaled up rapidly through contracting mechanisms with Non-Governmental Organisations (NGOs). The central thesis of this article is that, despite the good intentions of the BPHS, not enough has been done to overcome the barriers to accessing its services. This analysis, enabled through a review of the existing literature, identifies and categorises these barriers into the three access dimensions of: acceptability, affordability and availability. As each of these is explored individually, analysis will show the extent to which these barriers to access are a critical issue, consider the underlying reasons for their existence and evaluate the efforts to overcome these barriers. Understanding these barriers and the policies that have been implemented to address them is critical to the future of health system strengthening in Afghanistan.

Soft, curved electrode systems capable of integration on the auricle as a persistent brain–computer interface

PubMed Central

Norton, James J. S.; Lee, Dong Sup; Lee, Jung Woo; Lee, Woosik; Kwon, Ohjin; Won, Phillip; Jung, Sung-Young; Cheng, Huanyu; Jeong, Jae-Woong; Akce, Abdullah; Umunna, Stephen; Na, Ilyoun; Kwon, Yong Ho; Wang, Xiao-Qi; Liu, ZhuangJian; Paik, Ungyu; Huang, Yonggang; Bretl, Timothy; Yeo, Woon-Hong; Rogers, John A.

2015-01-01

Recent advances in electrodes for noninvasive recording of electroencephalograms expand opportunities collecting such data for diagnosis of neurological disorders and brain–computer interfaces. Existing technologies, however, cannot be used effectively in continuous, uninterrupted modes for more than a few days due to irritation and irreversible degradation in the electrical and mechanical properties of the skin interface. Here we introduce a soft, foldable collection of electrodes in open, fractal mesh geometries that can mount directly and chronically on the complex surface topology of the auricle and the mastoid, to provide high-fidelity and long-term capture of electroencephalograms in ways that avoid any significant thermal, electrical, or mechanical loading of the skin. Experimental and computational studies establish the fundamental aspects of the bending and stretching mechanics that enable this type of intimate integration on the highly irregular and textured surfaces of the auricle. Cell level tests and thermal imaging studies establish the biocompatibility and wearability of such systems, with examples of high-quality measurements over periods of 2 wk with devices that remain mounted throughout daily activities including vigorous exercise, swimming, sleeping, and bathing. Demonstrations include a text speller with a steady-state visually evoked potential-based brain–computer interface and elicitation of an event-related potential (P300 wave). PMID:25775550

Soft, curved electrode systems capable of integration on the auricle as a persistent brain-computer interface.

PubMed

Norton, James J S; Lee, Dong Sup; Lee, Jung Woo; Lee, Woosik; Kwon, Ohjin; Won, Phillip; Jung, Sung-Young; Cheng, Huanyu; Jeong, Jae-Woong; Akce, Abdullah; Umunna, Stephen; Na, Ilyoun; Kwon, Yong Ho; Wang, Xiao-Qi; Liu, ZhuangJian; Paik, Ungyu; Huang, Yonggang; Bretl, Timothy; Yeo, Woon-Hong; Rogers, John A

2015-03-31

Recent advances in electrodes for noninvasive recording of electroencephalograms expand opportunities collecting such data for diagnosis of neurological disorders and brain-computer interfaces. Existing technologies, however, cannot be used effectively in continuous, uninterrupted modes for more than a few days due to irritation and irreversible degradation in the electrical and mechanical properties of the skin interface. Here we introduce a soft, foldable collection of electrodes in open, fractal mesh geometries that can mount directly and chronically on the complex surface topology of the auricle and the mastoid, to provide high-fidelity and long-term capture of electroencephalograms in ways that avoid any significant thermal, electrical, or mechanical loading of the skin. Experimental and computational studies establish the fundamental aspects of the bending and stretching mechanics that enable this type of intimate integration on the highly irregular and textured surfaces of the auricle. Cell level tests and thermal imaging studies establish the biocompatibility and wearability of such systems, with examples of high-quality measurements over periods of 2 wk with devices that remain mounted throughout daily activities including vigorous exercise, swimming, sleeping, and bathing. Demonstrations include a text speller with a steady-state visually evoked potential-based brain-computer interface and elicitation of an event-related potential (P300 wave).

On the Feasibility of Intense Radial Velocity Surveys for Earth-twin Discoveries

NASA Astrophysics Data System (ADS)

Hall, Richard D.; Thompson, Samantha J.; Handley, Will; Queloz, Didier

2018-06-01

This work assesses the potential capability of the next generation of high-precision Radial Velocity (RV) instruments for Earth-twin exoplanet detection. From the perspective of the importance of data sampling, the Terra Hunting Experiment aims to do this through an intense series of nightly RV observations over a long baseline on a carefully selected target list, via the brand-new instrument HARPS3. This paper describes an end-to-end simulation of generating and processing such data to help us better understand the impact of uncharacterised stellar noise in the recovery of Earth-mass planets with orbital periods of the order of many months. We consider full Keplerian systems, realistic simulated stellar noise, instrument white noise, and location-specific weather patterns for our observation schedules. We use Bayesian statistics to assess various planetary models fitted to the synthetic data, and compare the successful planet recovery of the Terra Hunting Experiment schedule with a typical reference survey. We find that the Terra Hunting Experiment can detect Earth-twins in the habitable zones of solar-type stars, in single and multi-planet systems, and in the presence of stellar signals. Also that it out-performs a typical reference survey on accuracy of recovered parameters, and that it performs comparably to an uninterrupted space-based schedule.

Soft, curved electrode systems capable of integration on the auricle as a persistent brain–computer interface

DOE PAGES

Norton, James J. S.; Lee, Dong Sup; Lee, Jung Woo; ...

2015-03-16

Some recent advances in electrodes for noninvasive recording of electroencephalograms expand opportunities collecting such data for diagnosis of neurological disorders and brain–computer interfaces. Existing technologies, but, cannot be used effectively in continuous, uninterrupted modes for more than a few days due to irritation and irreversible degradation in the electrical and mechanical properties of the skin interface. We introduce a soft, foldable collection of electrodes in open, fractal mesh geometries that can mount directly and chronically on the complex surface topology of the auricle and the mastoid, to provide high-fidelity and long-term capture of electroencephalograms in ways that avoid any significantmore » thermal, electrical, or mechanical loading of the skin. Experimental and computational studies establish the fundamental aspects of the bending and stretching mechanics that enable this type of intimate integration on the highly irregular and textured surfaces of the auricle. Furthermore, cell level tests and thermal imaging studies establish the biocompatibility and wearability of such systems, with examples of high-quality measurements over periods of 2 wk with devices that remain mounted throughout daily activities including vigorous exercise, swimming, sleeping, and bathing. Demonstrations include a text speller with a steady-state visually evoked potential-based brain–computer interface and elicitation of an event-related potential (P300 wave).« less

A Fundamental Mathematical Model of a Microbial Predenitrification System

NASA Technical Reports Server (NTRS)

Hoo, Karlene A.

2005-01-01

Space flight beyond Low Earth Orbit requires sophisticated systems to support all aspects of the mission (life support, real-time communications, etc.). A common concern that cuts across all these systems is the selection of information technology (IT) methodology, software and hardware architectures to provide robust monitoring, diagnosis, and control support. Another dimension of the problem space is that different systems must be integrated seamlessly so that communication speed and data handling appear as a continuum (un-interrupted). One such team investigating this problem is the Advanced Integration Matrix (AIM) team whose role is to define the critical requirements expected of software and hardware to support an integrated approach to the command and control of Advanced Life Support (ALS) for future long-duration human space missions, including permanent human presence on the Moon and Mars. A goal of the AIM team is to set the foundation for testing criteria that will assist in specifying tasks, control schemes and test scenarios to validate and verify systems capabilities. This project is to contribute to the goals of the AIM team by assisting with controls planning for ALS. Control for ALS is an enormous problem it involves air revitalization, water recovery, food production, solids processing and crew. In more general terms, these systems can be characterized as involving both continuous and discrete processes, dynamic interactions among the sub-systems, nonlinear behavior due to the complex operations, and a large number of multivariable interactions due to the dimension of the state space. It is imperative that a baseline approach from which to measure performance is established especially when the expectation for the control system is complete autonomous control.

Disaster preparedness of dialysis patients for Hurricanes Gustav and Ike 2008.

PubMed

Kleinpeter, Myra A

2009-01-01

Hurricanes Katrina and Rita resulted in massive devastation of the Gulf Coast at Mississippi, Louisiana, and Texas during 2005. Because of those disasters, dialysis providers, nephrologists, and dialysis patients used disaster planning activities to work to mitigate the morbidity and mortality associated with the 2005 hurricane season for future events affecting dialysis patients. As Hurricane Gustav approached, anniversary events for Hurricane Katrina were postponed because of evacuation orders for nearly the entire Louisiana Gulf Coast. As part of the hurricane preparation, dialysis units reviewed the disaster plans of patients, and patients made preparation for evacuation. Upon evacuation, many patients returned to the dialysis units that had provided services during their exile from Hurricane Katrina; other patients went to other locations as part of their evacuation plan. Patients uniformly reported positive experiences with dialysis providers in their temporary evacuation communities, provided that those communities did not experience the effects of Hurricane Gustav. With the exception of evacuees to Baton Rouge, patients continued to receive their treatments uninterrupted. Because of extensive damage in the Baton Rouge area, resulting in widespread power losses and delayed restoration of power to hospitals and other health care facilities, some patients missed one treatment. However, as a result of compliance with disaster fluid and dietary recommendations, no adverse outcomes occurred. In most instances, patients were able to return to their home dialysis unit or a nearby unit to continue dialysis treatments within 4 - 5 days of Hurricane Gustav. Hurricane Ike struck the Texas Gulf Coast near Galveston, resulting in devastation of that area similar to the devastation seen in New Orleans after Katrina. The storm surge along the Louisiana Gulf Coast resulted in flooding that temporarily closed coastal dialysis units. Patients were prepared and experienced minimal interruption of dialysis services. Early planning and evacuation in the face of hurricane landfall--lessons learned from Hurricane Katrina in 2005--prevented disruption of treatment.

HERA: Illuminating Our Early Universe

NASA Astrophysics Data System (ADS)

DeBoer, David

2014-06-01

The Hydrogen Epoch of Reionization Arrays (HERA) roadmap is a staged plan for using the unique properties of the 21cm line from neutral hydrogen to probe our cosmic dawn, from the birth of the first stars and black holes, through the full reionization of the primordial intergalactic medium (IGM). HERA is a collaboration between the Precision Array Probing the Epoch of Reionization (PAPER), US-Murchison Widefield Array (MWA), and MIT Epoch of Reionization (MITEOR) teams.The first phase of the HERA roadmap entailed the operation of the PAPER and MWA telescopes to explore techniques and designs required to detect the primordial HI signal in the presence of radio continuum foreground emission some four orders of magnitude brighter. Studies with PAPER and the MWA have led to a new understanding of the interplay of foreground and instrumental systematics in the context of a three-dimensional cosmological intensity-mapping experiment. We are now able to remove foregrounds to the limits of our sensitivity with these instruments, culminating in the first physically meaningful upper limits on the power spectrum of 2 cm emission from reionization.Building on this understanding, the next stage of HERA entails a new 14m diameter antenna element that is optimized both for sensitivity and for minimizing foreground systematics. Arranging these elements in a compact hexagonal grid yields an array that facilitates calibration, leverages proven foreground removal techniques, and is scalable to large collecting areas. The HERA phase II will be located in the radio quiet environment of the SKA site in Karoo, South Africa, and have a sensitivity close to two orders of magnitude better than PAPER and the MWA, with broader frequency coverage, HERA can paint an uninterrupted picture through reionization, back to the end of the Dark Ages.This paper will present a summary of the current understanding of the signal characteristics and measurements and describe this planned HERA telescope to be built to detect and characterize the EoR power spectrum.

Filling in the juvenile magmatic gap: Evidence for uninterrupted Paleoproterozoic plate tectonics

NASA Astrophysics Data System (ADS)

Partin, C. A.; Bekker, A.; Sylvester, P. J.; Wodicka, N.; Stern, R. A.; Chacko, T.; Heaman, L. M.

2014-02-01

Despite several decades of research on growth of the continental crust, it remains unclear whether the production of juvenile continental crust has been continuous or episodic throughout the Precambrian. Models for episodic crustal growth have gained traction recently through compilations of global U-Pb zircon age frequency distributions interpreted to delineate peaks and lulls in crustal growth through geologic time. One such apparent trough in zircon age frequency distributions between ∼2.45 and 2.22 Ga is thought to represent a pause in crustal addition, resulting from a global shutdown of magmatic and tectonic processes. The ∼2.45-2.22 Ga magmatic shutdown model envisions a causal relationship between the cessation of plate tectonics and accumulation of atmospheric oxygen over the same period. Here, we present new coupled U-Pb, Hf, and O isotope data for detrital and magmatic zircon from the western Churchill Province and Trans-Hudson orogen of Canada, covering an area of approximately 1.3 million km2, that demonstrate significant juvenile crustal production during the ∼2.45-2.22 Ga time interval, and thereby argue against the magmatic shutdown hypothesis. Our data is corroborated by literature data showing an extensive 2.22-2.45 Ga record in both detrital and magmatic rocks on every continent, and suggests that the operation of plate tectonics continued throughout the early Paleoproterozoic, while atmospheric oxygen rose over the same time interval. We argue that uninterrupted plate tectonics between ∼2.45 and 2.22 Ga would have contributed to efficient burial of organic matter and sedimentary pyrite, and the consequent rise in atmospheric oxygen documented for this time interval.

Forgetting induced speeding: Can prospective memory failure account for drivers exceeding the speed limit?

PubMed

Bowden, Vanessa K; Visser, Troy A W; Loft, Shayne

2017-06-01

It is generally assumed that drivers speed intentionally because of factors such as frustration with the speed limit or general impatience. The current study examined whether speeding following an interruption could be better explained by unintentional prospective memory (PM) failure. In these situations, interrupting drivers may create a PM task, with speeding the result of drivers forgetting their newly encoded intention to travel at a lower speed after interruption. Across 3 simulated driving experiments, corrected or uncorrected speeding in recently reduced speed zones (from 70 km/h to 40 km/h) increased on average from 8% when uninterrupted to 33% when interrupted. Conversely, the probability that participants traveled under their new speed limit in recently increased speed zones (from 40 km/h to 70 km/h) increased from 1% when uninterrupted to 23% when interrupted. Consistent with a PM explanation, this indicates that interruptions lead to a general failure to follow changed speed limits, not just to increased speeding. Further testing a PM explanation, Experiments 2 and 3 manipulated variables expected to influence the probability of PM failures and subsequent speeding after interruptions. Experiment 2 showed that performing a cognitively demanding task during the interruption, when compared with unfilled interruptions, increased the probability of initially speeding from 1% to 11%, but that participants were able to correct (reduce) their speed. In Experiment 3, providing participants with 10s longer to encode the new speed limit before interruption decreased the probability of uncorrected speeding after an unfilled interruption from 30% to 20%. Theoretical implications and implications for road design interventions are discussed. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Effects of Health Insurance Interruption on Loss of Hypertension Control in Women With and Women Without HIV.

PubMed

Edmonds, Andrew; Ludema, Christina; Eron, Joseph J; Cole, Stephen R; Adedimeji, Adebola A; Cohen, Mardge H; Cooper, Hannah L; Fischl, Margaret; Johnson, Mallory O; Krause, Denise D; Merenstein, Dan; Milam, Joel; Wilson, Tracey E; Adimora, Adaora A

2017-12-01

Among low-income women with and without HIV, it is a priority to reduce age-related comorbidities, including hypertension and its sequelae. Because consistent health insurance access has been identified as an important factor in controlling many chronic diseases, we estimated the effects of coverage interruption on loss of hypertension control in a cohort of women in the United States. We analyzed prospective, longitudinal data from the Women's Interagency HIV Study. HIV-infected and HIV-uninfected women were included between 2005 and 2014 when they reported health insurance at consecutive biannual visits and had controlled hypertension, and were followed for any insurance break and loss of hypertension control. We estimated hazard ratios (HRs) by Cox proportional hazards regression with inverse-probability-of-treatment-and censoring weights (marginal structural models), and plotted the cumulative incidence of hypertension control loss. Among 890 HIV-infected women, the weighted HR for hypertension control loss comparing health insurance interruption to uninterrupted coverage was 1.37 (95% confidence interval [CI], 0.99-1.91). Inclusion of AIDS Drug Assistance Program (ADAP) participation with health insurance modestly increased the HR (1.47; 95% CI, 1.04-2.07). Analysis of 272 HIV-uninfected women yielded a similar HR (1.39; 95% CI, 0.88-2.21). Additionally, there were indications of uninterrupted coverage having a protective effect on hypertension when compared with the natural course in HIV-infected (HR, 0.82; 95% CI, 0.61-1.11) and HIV-uninfected (HR, 0.78; 95% CI, 0.52-1.19) women. This study provides evidence that health insurance continuity promotes hypertension control in key populations. Interventions that ensure coverage stability and ADAP access should be a policy priority.

Estimates of the continuously publishing core in the scientific workforce.

PubMed

Ioannidis, John P A; Boyack, Kevin W; Klavans, Richard

2014-01-01

The ability of a scientist to maintain a continuous stream of publication may be important, because research requires continuity of effort. However, there is no data on what proportion of scientists manages to publish each and every year over long periods of time. Using the entire Scopus database, we estimated that there are 15,153,100 publishing scientists (distinct author identifiers) in the period 1996-2011. However, only 150,608 (<1%) of them have published something in each and every year in this 16-year period (uninterrupted, continuous presence [UCP] in the literature). This small core of scientists with UCP are far more cited than others, and they account for 41.7% of all papers in the same period and 87.1% of all papers with >1000 citations in the same period. Skipping even a single year substantially affected the average citation impact. We also studied the birth and death dynamics of membership in this influential UCP core, by imputing and estimating UCP-births and UCP-deaths. We estimated that 16,877 scientists would qualify for UCP-birth in 1997 (no publication in 1996, UCP in 1997-2012) and 9,673 scientists had their UCP-death in 2010. The relative representation of authors with UCP was enriched in Medical Research, in the academic sector and in Europe/North America, while the relative representation of authors without UCP was enriched in the Social Sciences and Humanities, in industry, and in other continents. The proportion of the scientific workforce that maintains a continuous uninterrupted stream of publications each and every year over many years is very limited, but it accounts for the lion's share of researchers with high citation impact. This finding may have implications for the structure, stability and vulnerability of the scientific workforce.

Positive effects of Red Bull® Energy Drink on driving performance during prolonged driving.

PubMed

Mets, Monique A J; Ketzer, Sander; Blom, Camilla; van Gerven, Maartje H; van Willigenburg, Gitta M; Olivier, Berend; Verster, Joris C

2011-04-01

The purpose of this study was to examine if Red Bull® Energy Drink can counteract sleepiness and driving impairment during prolonged driving. Twenty-four healthy volunteers participated in this double-blind placebo-controlled crossover study. After 2 h of highway driving in the STISIM driving simulator, subjects had a 15-min break and consumed Red Bull® Energy Drink (250 ml) or placebo (Red Bull® Energy Drink without the functional ingredients: caffeine, taurine, glucuronolactone, B vitamins (niacin, pantothenic acid, B6, B12), and inositol) before driving for two additional hours. A third condition comprised 4 h of uninterrupted driving. Primary parameter was the standard deviation of lateral position (SDLP), i.e., the weaving of the car. Secondary parameters included SD speed, subjective driving quality, sleepiness, and mental effort to perform the test. No significant differences were observed during the first 2 h of driving. Red Bull® Energy Drink significantly improved driving relative to placebo: SDLP was significantly reduced during the 3rd (p < 0.046) and 4th hour of driving (p < 0.011). Red Bull® Energy Drink significantly reduced the standard deviation of speed (p < 0.004), improved subjective driving quality (p < 0.0001), and reduced mental effort to perform the test (p < 0.024) during the 3rd hour of driving. Subjective sleepiness was significantly decreased during both the 3rd and 4th hour of driving after Red Bull® Energy Drink (p < 0.001 and p < 0.009, respectively). Relative to uninterrupted driving, Red Bull® Energy Drink significantly improved each parameter. Red Bull® Energy Drink significantly improves driving performance and reduces driver sleepiness during prolonged highway driving.

Myocardial perfusion and oxidative stress after 21% vs. 100% oxygen ventilation and uninterrupted chest compressions in severely asphyxiated piglets.

PubMed

Solevåg, Anne Lee; Schmölzer, Georg M; O'Reilly, Megan; Lu, Min; Lee, Tze-Fun; Hornberger, Lisa K; Nakstad, Britt; Cheung, Po-Yin

2016-09-01

Despite the minimal evidence, neonatal resuscitation guidelines recommend using 100% oxygen when chest compressions (CC) are needed. Uninterrupted CC in adult cardiopulmonary resuscitation (CPR) may improve CPR hemodynamics. We aimed to examine 21% oxygen (air) vs. 100% oxygen in 3:1 CC:ventilation (C:V) CPR or continuous CC with asynchronous ventilation (CCaV) in asphyxiated newborn piglets following cardiac arrest. Piglets (1-3 days old) were progressively asphyxiated until cardiac arrest and randomized to 4 experimental groups (n=8 each): air and 3:1 C:V CPR, 100% oxygen and 3:1 C:V CPR, air and CCaV, or 100% oxygen and CCaV. Time to return of spontaneous circulation (ROSC), mortality, and clinical and biochemical parameters were compared between groups. We used echocardiography to measure left ventricular (LV) stroke volume at baseline, at 30min and 4h after ROSC. Left common carotid artery blood pressure was measured continuously. Time to ROSC (heart rate ≥100min(-1)) ranged from 75 to 592s and mortality 50-75%, with no differences between groups. Resuscitation with air was associated with higher LV stroke volume after ROSC and less myocardial oxidative stress compared to 100% oxygen groups. CCaV was associated with lower mean arterial blood pressure after ROSC and higher myocardial lactate than those of 3:1 C:V CPR. In neonatal asphyxia-induced cardiac arrest, using air during CC may reduce myocardial oxidative stress and improve cardiac function compared to 100% oxygen. Although overall recovery may be similar, CCaV may impair tissue perfusion compared to 3:1 C:V CPR. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen.

PubMed

Braak, H; Rüb, U; Gai, W P; Del Tredici, K

2003-05-01

The progressive, neurodegenerative process underlying idiopathic Parkinson's disease is associated with the formation of proteinaceous inclusion bodies that involve a few susceptible neuronal types of the human nervous system. In the lower brain stem, the process begins in the dorsal motor nucleus of the vagus nerve and advances from there essentially upwards through susceptible regions of the medulla oblongata, pontine tegmentum, midbrain, and basal forebrain until it reaches the cerebral cortex. With time, multiple components of the autonomic, limbic, and motor systems become severely impaired. All of the vulnerable subcortical grays and cortical areas are closely interconnected. Incidental cases of idiopathic Parkinson's disease may show involvement of both the enteric nervous system and the dorsal motor nucleus of the vagus nerve. This observation, combined with the working hypothesis that the stereotypic topographic expansion pattern of the lesions may resemble that of a falling row of dominos, prompts the question whether the disorder might originate outside of the central nervous system, caused by a yet unidentified pathogen that is capable of passing the mucosal barrier of the gastrointestinal tract and, via postganglionic enteric neurons, entering the central nervous system along unmyelinated praeganglionic fibers generated from the visceromotor projection cells of the vagus nerve. By way of retrograde axonal and transneuronal transport, such a causative pathogen could reach selectively vulnerable subcortical nuclei and, unimpeded, gain access to the cerebral cortex. The here hypothesized mechanism offers one possible explanation for the sequential and apparently uninterrupted manner in which vulnerable brain regions, subcortical grays and cortical areas become involved in idiopathic Parkinson's disease.

Arcus: exploring the formation and evolution of clusters, galaxies, and stars

NASA Astrophysics Data System (ADS)

Smith, R. K.; Abraham, M.; Allured, R.; Bautz, M.; Bookbinder, J.; Bregman, J.; Brenneman, L.; Brickhouse, N. S.; Burrows, D.; Burwitz, V.; Cheimets, P. N.; Costantini, E.; Dawson, S.; DeRoo, C.; Falcone, A.; Foster, A. R.; Gallo, L.; Grant, C. E.; Günther, H. M.; Heilmann, R. K.; Hertz, E.; Hine, B.; Huenemoerder, D.; Kaastra, J. S.; Kreykenbohm, I.; Madsen, K. K.; McEntaffer, R.; Miller, E.; Miller, J.; Morse, E.; Mushotzky, R.; Nandra, K.; Nowak, M.; Paerels, F.; Petre, R.; Poppenhaeger, K.; Ptak, A.; Reid, P.; Sanders, J.; Schattenburg, M.; Schulz, N.; Smale, A.; Temi, P.; Valencic, L.; Walker, S.; Willingale, R.; Wilms, J.; Wolk, S. J.

2017-08-01

Arcus, a Medium Explorer (MIDEX) mission, was selected by NASA for a Phase A study in August 2017. The observatory provides high-resolution soft X-ray spectroscopy in the 12-50Å bandpass with unprecedented sensitivity: effective areas of >450 cm2 and spectral resolution >2500. The Arcus key science goals are (1) to measure the effects of structure formation imprinted upon the hot baryons that are predicted to lie in extended halos around galaxies, groups, and clusters, (2) to trace the propagation of outflowing mass, energy, and momentum from the vicinity of the black hole to extragalactic scales as a measure of their feedback and (3) to explore how stars, circumstellar disks and exoplanet atmospheres form and evolve. Arcus relies upon the same 12m focal length grazing-incidence silicon pore X-ray optics (SPO) that ESA has developed for the Athena mission; the focal length is achieved on orbit via an extendable optical bench. The focused X-rays from these optics are diffracted by high-efficiency Critical-Angle Transmission (CAT) gratings, and the results are imaged with flight-proven CCD detectors and electronics. The power and telemetry requirements on the spacecraft are modest. Mission operations are straightforward, as most observations will be long ( 100 ksec), uninterrupted, and pre-planned, although there will be capabilities to observe sources such as tidal disruption events or supernovae with a 3 day turnaround. Following the 2nd year of operation, Arcus will transition to a proposal-driven guest observatory facility.

Kagome fiber based ultrafast laser microsurgery probe delivering micro-Joule pulse energies

PubMed Central

Subramanian, Kaushik; Gabay, Ilan; Ferhanoğlu, Onur; Shadfan, Adam; Pawlowski, Michal; Wang, Ye; Tkaczyk, Tomasz; Ben-Yakar, Adela

2016-01-01

We present the development of a 5 mm, piezo-actuated, ultrafast laser scalpel for fast tissue microsurgery. Delivery of micro-Joules level energies to the tissue was made possible by a large, 31 μm, air-cored inhibited-coupling Kagome fiber. We overcome the fiber’s low NA by using lenses made of high refractive index ZnS, which produced an optimal focusing condition with 0.23 NA objective. The optical design achieved a focused laser spot size of 4.5 μm diameter covering a 75 × 75 μm2 scan area in a miniaturized setting. The probe could deliver the maximum available laser power, achieving an average fluence of 7.8 J/cm2 on the tissue surface at 62% transmission efficiency. Such fluences could produce uninterrupted, 40 μm deep cuts at translational speeds of up to 5 mm/s along the tissue. We predicted that the best combination of speed and coverage exists at 8 mm/s for our conditions. The onset of nonlinear absorption in ZnS, however, limited the probe’s energy delivery capabilities to 1.4 μJ for linear operation at 1.5 picosecond pulse-widths of our fiber laser. Alternatives like broadband CaF2 crystals should mitigate such nonlinear limiting behavior. Improved opto-mechanical design and appropriate material selection should allow substantially higher fluence delivery and propel such Kagome fiber-based scalpels towards clinical translation. PMID:27896003

Skylab: A beginning. [astronaut performance in extended space exploration

NASA Technical Reports Server (NTRS)

Dietlein, L. F.

1974-01-01

Skylab biomedical experience indicates that man adapts well to and functions effectively in the space environment for time periods approaching three months. Appropriate dietary intake coupled with adequate, programmed exercise, sleep, work and recreation periods are essential to crew health and well being. No untoward physiological responses have been noted that would preclude longer duration space flights, but more research is required in order to understand the mechanisms involved in the observed responses. Remedial or preventive measures may be required for Mars-type missions, and further study of man in earth orbit for an uninterrupted six-month period should ideally precede this Mars-type mission.

Definition of tolerance to continuous hyperoxia in man - An abstract report of Predictive Studies V

NASA Technical Reports Server (NTRS)

Lambertsen, C. J.; Clark, J. M.; Gelfand, R.; Pisarello, J. B.; Cobbs, W. H.

1987-01-01

The overall goals, design, and procedures of Predictive Studies V are discussed as well as the specific elements of neural effects produced by prolonged hyperoxia. It is noted that Predictive Studies V study of oxygen poisoning in normal men during uninterrupted exposures to oxygen over the range of hyperbaric oxygen exposure most useful in diving, the treatment of gas lesion diseases, and general hyperbaric medicine. It is found that, throughout the study, the most striking observations were related to effects on visual function, on the lung, and the probable interactions of preconvulsive neural activity with effects on cardiovascular and respiratory-pulmonary functions.

Long-term stable lung function and second uncomplicated pregnancy on sirolimus in lymphangioleiomyomatosis (LAM).

PubMed

Faehling, Martin; Wienhausen-Wilke, Vera; Fallscheer, Sabine; Trinajstic-Schulz, B; Weber, J; Leschke, Matthias

2015-09-14

We present a patient with lymphangioleiomyomatosis (LAM) on long-term sirolimus (now 79 months) who has had a second successful pregnancy. The second pregnancy on uninterrupted low-dose sirolimus (plasma levels 3-5 mg/L) was uncomplicated both with respect to mother and child suggesting that low-dose sirolimus might be safe in selected pregnant patients with stable LAM. The long-term time course in this patient is in agreement with recent reports of a long-term beneficial effect of sirolimus in LAM. In this patient, the pregnancies did not seem to impair the long-term improvement of lung-function on sirolimus.

The Physics Analysis of a Gas Attenuator with Argon as a Working Gas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ryutov,, D.D.

2010-12-07

A gas attenuator is an important element of the LCLS facility. The attenuator must operate in a broad range of x-ray energies, provide attenuation coefficient between 1 and 10{sup 4} with the accuracy of 1% and, at the same time, be reliable and allow for many months of un-interrupted operation. S. Shen has recently carried out a detailed design study of the attenuator based on the use of nitrogen as a working gas. In this note we assess the features of the attenuator based on the use of argon. We concentrate on the physics issues, not the design features.

Transducer for downhole drilling components

DOEpatents

Hall, David R; Fox, Joe R

2006-05-30

A robust transmission element for transmitting information between downhole tools, such as sections of drill pipe, in the presence of hostile environmental conditions, such as heat, dirt, rocks, mud, fluids, lubricants, and the like. The transmission element maintains reliable connectivity between transmission elements, thereby providing an uninterrupted flow of information between drill string components. A transmission element is mounted within a recess proximate a mating surface of a downhole drilling component, such as a section of drill pipe. The transmission element may include an annular housing forming a trough, an electrical conductor disposed within the trough, and an MCEI material disposed between the annular housing and the electrical conductor.

Comparative Study of Two Systems for the Assessment of Static Balance in Veterans with Mild Traumatic Brain Injury.

PubMed

Leland, Azadeh; Tavakol, Kamran; Scholten, Joel; Bakhshi, Simin; Kelarestaghi, Kaveh

2018-04-01

Traditionally, the diagnosis of postural instability relies on the clinical examination of static balance. In recent years, computerized technologies have provided a new approach for the accurate detection of positional changes during functional balance. The aim of this study was to investigate the similarities and differences between two electronic systems, NeuroCom and BioSensics , and their application in the clinical assessment of impaired balance in American veterans. We examined the sway around the center of mass during static balance conditions in 25 veterans with mild traumatic brain injury, using the two electronic systems. These patients met the inclusion criteria and were assessed for their impaired balance at the District of Columbia Veterans Affair Medical Center, Washington, DC, USA. There were six static balance tests conducted on either NeuroCom or BioSensics system in triplicate. Of the data for 36 sets of statistical data analyses, there were significant correlations among those for eight data sets (22.2%) between the two systems. The strongest positive correlation between the data from the two systems was found during the baseline test, when inputs from visual, vestibular and sensorymotor sources were uninterrupted. The data from the remaining experimental conditions did not correlate significantly with one another. Both NeuroCom and BioSensics provided comparable data in eight out of 36 experimental conditions in the assessment of static balance in patients with mild traumatic brain injury. The findings clarified the ambiguities in the application of NeuroCom versus BioSensics, provided new knowledge for the field of physical medicine and rehabilitation, and improved the clinical assessment of static balance in patients with mTBI.

Production characteristics of lettuce Lactuca sativa L. in the frame of the first crop tests in the Higher Plant Chamber integrated into the MELiSSA Pilot Plant

NASA Astrophysics Data System (ADS)

Tikhomirova, Natalia; Lawson, Jamie; Stasiak, Michael; Dixon, Mike; Paille, Christel; Peiro, Enrique; Fossen, Arnaud; Godia, Francesc

Micro-Ecological Life Support System Alternative (MELiSSA) is an artificial closed ecosystem that is considered a tool for the development of a bioregenerative life support system for manned space missions. One of the five compartments of MELiSSA loop -Higher Plant Chamber was recently integrated into the MELiSSA Pilot Plant facility at Universitat Aut`noma deo Barcelona. The main contributions expected by integration of this photosynthetic compartment are oxygen, water, vegetable food production and CO2 consumption. Production characteristics of Lactuca sativa L., as a MELiSSA candidate crop, were investigated in this work in the first crop experiments in the MELiSSA Pilot Plant facility. The plants were grown in batch culture and totaled 100 plants with a growing area 5 m long and 1 m wide in a sealed controlled environment. Several replicates of the experiments were carried out with varying duration. It was shown that after 46 days of lettuce cultivation dry edible biomass averaged 27, 2 g per plant. However accumulation of oxygen in the chamber, which required purging of the chamber, and decrease in the food value of the plants was observed. Reducing the duration of the tests allowed uninterrupted test without opening the system and also allowed estimation of the crop's carbon balance. Results of productivity, tissue composition, nutrient uptake and canopy photosynthesis of lettuce regardless of test duration are discussed in the paper.

A plea for "variational neuroethology". Comment on "Answering Schrödinger's question: A free-energy formulation" by M.J. Desormeau Ramstead et al.

NASA Astrophysics Data System (ADS)

Daunizeau, Jean

2018-03-01

What is life? According to Erwin Schrödinger [13], the living cell departs from other physical systems in that it - apparently - resists the second law of thermodynamics by restricting the dynamical repertoire (minimizing the entropy) of its physiological states. This is a physical rephrasing of Claude Bernard's biological notion of homeostasis, namely: the capacity of living systems to self-organize in order to maintain the stability of their internal milieu despite uninterrupted exchanges with an ever-altering external environment [2]. The important point here is that physical systems can neither identify nor prevent a state of high entropy. The Free Energy Principle or FEP was originally proposed as a mathematical description of how the brain actually solves this issue [4]. In line with the Bayesian brain hypothesis, the FEP views the brain as a hierarchical statistical learning machine, endowed with the imperative of minimizing Free Energy, i.e. prediction error. Action prescription under the FEP, however, does not follow standard Bayesian decision theory. Rather, action is assumed to further minimize Free Energy, which makes the active brain a self-fulfilling prophecy machine [6]. This is adaptive, under the assumption that evolution has equipped the brain with innate priors centered on homeostatic set points. In turn, avoiding (surprising) violations of such prior predictions implements homeostatic regulation [10], which becomes increasingly anticipatory as learning unfolds over the course of ontological development [5].

A new approach for flow-through respirometry measurements in humans

PubMed Central

Ingebrigtsen, Jan P.; Bergouignan, Audrey; Ohkawara, Kazunori; Kohrt, Wendy M.; Lighton, John R. B.

2010-01-01

Indirect whole room calorimetry is commonly used in studies of human metabolism. These calorimeters can be configured as either push or pull systems. A major obstacle to accurately calculating gas exchange rates in a pull system is that the excurrent flow rate is increased above the incurrent flow rate, because the organism produces water vapor, which also dilutes the concentrations of respiratory gasses in the excurrent sample. A common approach to this problem is to dry the excurrent gasses prior to measurement, but if drying is incomplete, large errors in the calculated oxygen consumption will result. The other major potential source of error is fluctuations in the concentration of O2 and CO2 in the incurrent airstream. We describe a novel approach to measuring gas exchange using a pull-type whole room indirect calorimeter. Relative humidity and temperature of the incurrent and excurrent airstreams are measured continuously using high-precision, relative humidity and temperature sensors, permitting accurate measurement of water vapor pressure. The excurrent flow rates are then adjusted to eliminate the flow contribution from water vapor, and respiratory gas concentrations are adjusted to eliminate the effect of water vapor dilution. In addition, a novel switching approach is used that permits constant, uninterrupted measurement of the excurrent airstream while allowing frequent measurements of the incurrent airstream. To demonstrate the accuracy of this approach, we present the results of validation trials compared with our existing system and metabolic carts, as well as the results of standard propane combustion tests. PMID:20200135

The Influence of Inherited Topography and/or Tectonics on Paleo-channel Systems and Incised Valleys Offshore of South Carolina

NASA Astrophysics Data System (ADS)

Long, A. M.; Hill, J. C.

2016-12-01

The Quaternary paleo-channel and incised valley systems of the Southeastern United States have been well documented onshore; however, few studies have focused on the positions and fill histories of these systems on the continental shelf. The effects of inherited topography can be studied through the integration of seismo-acoustic and core data. Existing offshore datasets have been used to document underlying structural and stratigraphic fabrics deeper than the Quaternary in the sedimentary record. By integrating these results with the published tectonic setting and onshore interpretations, some of the controls on paleo-channel/incised valley positions can be inferred. Preliminary results suggest the stress caused by the uplift along the Cape Fear Arch has been accommodated by shallow folding and reactivation of deeper structures in the South Carolina offshore province. The resultant topography may have dictated both the position and geometry of the fluvial incisions across the shelf. This in turn influences the accommodation space available to be filled in as sea level fluctuates. The depositional facies within the paleo-channel and incised valley range from single, uninterrupted fill to complex and repeated scour and fill with at least four different episodes of erosion and deposition. The observations and interpretations proposed here are the first steps in unraveling the complex interplay between sea level, climate, and tectonic changes on the morphology and stratigraphy of incised valleys and paleo-channels observed offshore of South Carolina.

Partial Sleep Deprivation Attenuates the Positive Affective System: Effects Across Multiple Measurement Modalities.

PubMed

Finan, Patrick H; Quartana, Phillip J; Remeniuk, Bethany; Garland, Eric L; Rhudy, Jamie L; Hand, Matthew; Irwin, Michael R; Smith, Michael T

2017-01-01

Ample behavioral and neurobiological evidence links sleep and affective functioning. Recent self-report evidence suggests that the affective problems associated with sleep loss may be stronger for positive versus negative affective state and that those effects may be mediated by changes in electroencepholographically measured slow wave sleep (SWS). In the present study, we extend those preliminary findings using multiple measures of affective functioning. In a within-subject randomized crossover experiment, we tested the effects of one night of sleep continuity disruption via forced awakenings (FA) compared to one night of uninterrupted sleep (US) on three measures of positive and negative affective functioning: self-reported affective state, affective pain modulation, and affect-biased attention. The study was set in an inpatient clinical research suite. Healthy, good sleeping adults (N = 45) were included. Results indicated that a single night of sleep continuity disruption attenuated positive affective state via FA-induced reductions in SWS. Additionally, sleep continuity disruption attenuated the inhibition of pain by positive affect as well as attention bias to positive affective stimuli. Negative affective state, negative affective pain facilitation, nor negative attention bias were altered by sleep continuity disruption. The present findings, observed across multiple measures of affective function, suggest that sleep continuity disruption has a stronger influence on the positive affective system relative to the negative affective affective system. © Sleep Research Society 2016. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.

Development of a bench-top device for parallel climate-controlled recordings of neuronal cultures activity with microelectrode arrays.

PubMed

Regalia, Giulia; Biffi, Emilia; Achilli, Silvia; Ferrigno, Giancarlo; Menegon, Andrea; Pedrocchi, Alessandra

2016-02-01

Two binding requirements for in vitro studies on long-term neuronal networks dynamics are (i) finely controlled environmental conditions to keep neuronal cultures viable and provide reliable data for more than a few hours and (ii) parallel operation on multiple neuronal cultures to shorten experimental time scales and enhance data reproducibility. In order to fulfill these needs with a Microelectrode Arrays (MEA)-based system, we designed a stand-alone device that permits to uninterruptedly monitor neuronal cultures activity over long periods, overcoming drawbacks of existing MEA platforms. We integrated in a single device: (i) a closed chamber housing four MEAs equipped with access for chemical manipulations, (ii) environmental control systems and embedded sensors to reproduce and remotely monitor the standard in vitro culture environment on the lab bench (i.e. in terms of temperature, air CO2 and relative humidity), and (iii) a modular MEA interface analog front-end for reliable and parallel recordings. The system has been proven to assure environmental conditions stable, physiological and homogeneos across different cultures. Prolonged recordings (up to 10 days) of spontaneous and pharmacologically stimulated neuronal culture activity have not shown signs of rundown thanks to the environmental stability and have not required to withdraw the cells from the chamber for culture medium manipulations. This system represents an effective MEA-based solution to elucidate neuronal network phenomena with slow dynamics, such as long-term plasticity, effects of chronic pharmacological stimulations or late-onset pathological mechanisms. © 2015 Wiley Periodicals, Inc.

STSE: Spatio-Temporal Simulation Environment Dedicated to Biology.

PubMed

Stoma, Szymon; Fröhlich, Martina; Gerber, Susanne; Klipp, Edda

2011-04-28

Recently, the availability of high-resolution microscopy together with the advancements in the development of biomarkers as reporters of biomolecular interactions increased the importance of imaging methods in molecular cell biology. These techniques enable the investigation of cellular characteristics like volume, size and geometry as well as volume and geometry of intracellular compartments, and the amount of existing proteins in a spatially resolved manner. Such detailed investigations opened up many new areas of research in the study of spatial, complex and dynamic cellular systems. One of the crucial challenges for the study of such systems is the design of a well stuctured and optimized workflow to provide a systematic and efficient hypothesis verification. Computer Science can efficiently address this task by providing software that facilitates handling, analysis, and evaluation of biological data to the benefit of experimenters and modelers. The Spatio-Temporal Simulation Environment (STSE) is a set of open-source tools provided to conduct spatio-temporal simulations in discrete structures based on microscopy images. The framework contains modules to digitize, represent, analyze, and mathematically model spatial distributions of biochemical species. Graphical user interface (GUI) tools provided with the software enable meshing of the simulation space based on the Voronoi concept. In addition, it supports to automatically acquire spatial information to the mesh from the images based on pixel luminosity (e.g. corresponding to molecular levels from microscopy images). STSE is freely available either as a stand-alone version or included in the linux live distribution Systems Biology Operational Software (SB.OS) and can be downloaded from http://www.stse-software.org/. The Python source code as well as a comprehensive user manual and video tutorials are also offered to the research community. We discuss main concepts of the STSE design and workflow. We demonstrate it's usefulness using the example of a signaling cascade leading to formation of a morphological gradient of Fus3 within the cytoplasm of the mating yeast cell Saccharomyces cerevisiae. STSE is an efficient and powerful novel platform, designed for computational handling and evaluation of microscopic images. It allows for an uninterrupted workflow including digitization, representation, analysis, and mathematical modeling. By providing the means to relate the simulation to the image data it allows for systematic, image driven model validation or rejection. STSE can be scripted and extended using the Python language. STSE should be considered rather as an API together with workflow guidelines and a collection of GUI tools than a stand alone application. The priority of the project is to provide an easy and intuitive way of extending and customizing software using the Python language.

System importance measures: A new approach to resilient systems-of-systems

NASA Astrophysics Data System (ADS)

Uday, Payuna

Resilience is the ability to withstand and recover rapidly from disruptions. While this attribute has been the focus of research in several fields, in the case of system-of-systems (SoSs), addressing resilience is particularly interesting and challenging. As infrastructure SoSs, such as power, transportation, and communication networks, grow in complexity and interconnectivity, measuring and improving the resilience of these SoSs is vital in terms of safety and providing uninterrupted services. The characteristics of systems-of-systems make analysis and design of resilience challenging. However, these features also offer opportunities to make SoSs resilient using unconventional methods. In this research, we present a new approach to the process of resilience design. The core idea behind the proposed design process is a set of system importance measures (SIMs) that identify systems crucial to overall resilience. Using the results from the SIMs, we determine appropriate strategies from a list of design principles to improve SoS resilience. The main contribution of this research is the development of an aid to design that provides specific guidance on where and how resources need to be targeted. Based on the needs of an SoS, decision-makers can iterate through the design process to identify a set of practical and effective design improvements. We use two case studies to demonstrate how the SIM-based design process can inform decision-making in the context of SoS resilience. The first case study focuses on a naval warfare SoS and describes how the resilience framework can leverage existing simulation models to support end-to-end design. We proceed through stages of the design approach using an agent-based model (ABM) that enables us to demonstrate how simulation tools and analytical models help determine the necessary inputs for the design process and, subsequently, inform decision-making regarding SoS resilience. The second case study considers the urban transportation network in Boston. This case study focuses on interpreting the results of the resilience framework and on describing how they can be used to guide design choices in large infrastructure networks. We use different resilience maps to highlight the range of design-related information that can be obtained from the framework. Specific advantages of the SIM-based resilience design include: (1) incorporates SoS- specific features within existing risk-based design processes - the SIMs determine the relative importance of different systems based on their impacts on SoS-level performance, and suggestions for resilience improvement draw from design options that leverage SoS- specific characteristics, such as the ability to adapt quickly (such as add new systems or re-task existing ones) and to provide partial recovery of performance in the aftermath of a disruption; (2) allows rapid understanding of different areas of concern within the SoS - the visual nature of the resilience map (a key outcome of the SIM analysis) provides a useful way to summarize the current resilience of the SoS as well as point to key systems of concern; and (3) provides a platform for multiple analysts and decision- makers to study, modify, discuss and document options for SoS.

Technology transfer for DOE's office of buildings and community systems: assessment and strategies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, M.A.; Jones, D.W.; Kolb, J.O.

1986-07-01

The uninterrupted availability of oil supplies over the past several years and the moderation of energy price increases has sent signals to consumers and decision-makers in the buildings industry that the ''energy crisis'' is over. As a result, efforts to promote energy-conserving technologies must emphasize benefits other than BTU savings. The improved ambience of daylit spaces and the lower first costs associated with installing down-sized HVAC systems in ''tight'' buildings are examples of benefits which are likely to more influential than estimates of energy saved. Successful technology transfer requires that an R and D product have intrinsic value and thatmore » these values be effectively communicated to potential users. Active technology transfer programs are more effective than passive ones. Transfer activities should involve more than simply making information available to those who seek it. Information should be tailored to meet the needs of specific user groups and disseminated through those channels which users normally employ. In addition to information dissemination, successful technology transfer involves the management of intellectual property, including patented inventions, copyrights, technical data, and rights to future inventions. When the public can best benefit from an invention through commercialization of a new product, the exclusivity necessary to protect the investment from copiers should be provided. Most federal technology transfer programs concentrate on information exchange and largely avoid intellectual property transfers.« less

Dye injection for predicting pesticide movement in micro-irrigated polyethylene film mulch beds.

PubMed

Csinos, Alex S; Laska, James E; Childers, Stan

2002-04-01

A new method is described for tracing water movement in polyethylene film covered soil beds. Dye was delivered via a drip tape micro-irrigation system which was placed in the bed as the soil beds were shaped and covered with polyethylene film. The dye was injected into the system and irrigated with water for 4-24 h at 0.41-1.38 bar (41-138 kPa) pressure depending on the experiment. The dye appeared as blue circles on the soil surface within 20 min of injection and produced a three-dimensional pattern in the soil profile. Injection-irrigation-pressure scenarios were evaluated by measuring dye movement directly below and between emitters by sliding fabricated blades vertically into the bed at the desired examination point and excavating the soil away from the blade. The dye typically produced a U shape on the face of the bed and the area was calculated for each of these exposed faces. The area increased as the length of irrigation and water pressure increased. Interrupted irrigation (pulsing) scenarios did not alter the calculated areas encompassed by the dye compared to uninterrupted irrigation scenarios. The blue dye provided a direct, inexpensive and easy method of visualizing water movement in soil beds. This information will be used to optimize application of emulsifiable plant-care products in polyethylene film mulch beds.

Matrix isolation apparatus with extended sample collection capability

DOEpatents

Reedy, Gerald T.

1987-01-01

A gas-sample collection device provides for the matrix isolation of increased amounts of a sample material for spectrographic analysis from a gas chromatographic separation. The device includes an evacuated sample collection chamber containing a disc-like specular carousel having a generally circular lateral surface upon which the sample is deposited in an inert gas matrix for infrared (IR) spectral analysis. The evacuated sample chamber is mounted in a fixed manner and is coupled to and supports a rotating cryostatic coupler which, in turn, supports the specular carousel within the collection chamber. A rotational drive system connected to the cryostatic coupler provides for its rotational displacement as well as that of the sample collecting carousel. In addition, rotation of the cryostatic coupler effects vertical displacement of the carousel to permit the collection of an extended sample band in a helical configuration on the entire lateral surface of the carousel. The various components of the carousel's angular/linear displacement drive system are located exterior to the cryostatic coupler for easy access and improved operation. The cryostatic coupler includes a 360.degree. rotary union assembly for permitting the delivery of a high pressure working fluid to the cryostatic coupler in a continuous flow manner for maintaining the specular carousel at a low temperature, e.g., 10.degree.-20.degree. K., for improved uninterrupted gas sample collection and analysis.

Continuous single pulse resolved measurement of beam diameters at 200 kHz using optical transmission filters

NASA Astrophysics Data System (ADS)

Fruechtenicht, Johannes; Letsch, Andreas; Voss, Andreas; Abdou Ahmed, Marwan; Graf, Thomas

2012-02-01

We present a novel laser beam measurement setup which allows the determination of the beam diameter for each single pulse of a pulsed laser beam at repetition rates of up to 200 kHz. This is useful for online process-parameter control e.g. in micromachining or for laser source characterization. Basically, the developed instrument combines spatial transmission filters specially designed for instantaneous optical determination of the second order moments of the lateral intensity distribution of the light beam and photodiodes coupled to customized electronics. The acquisition is computer-based, enabling real-time operation for online monitoring or control. It also allows data storage for a later analysis and visualization of the measurement results. The single-pulse resolved beam diameter can be measured and recorded without any interruption for an unlimited number of pulses. It is only limited by the capacity of the data storage means. In our setup a standard PC and hard-disk provided 2 hours uninterrupted operation and recording of varying beam diameters at 200 kHz. This is about three orders of magnitude faster than other systems. To calibrate our device we performed experiments in cw and pulsed regimes and the obtained results were compared to those obtained with a commercial camera based system. Only minor deviations of the beam diameter values between the two instruments were observed, proving the reliability of our approach.

A Fuzzy Inference System for Closed-Loop Deep Brain Stimulation in Parkinson's Disease.

PubMed

Camara, Carmen; Warwick, Kevin; Bruña, Ricardo; Aziz, Tipu; del Pozo, Francisco; Maestú, Fernando

2015-11-01

Parkinsons disease is a complex neurodegenerative disorder for which patients present many symptoms, tremor being the main one. In advanced stages of the disease, Deep Brain Stimulation is a generalized therapy which can significantly improve the motor symptoms. However despite its beneficial effects on treating the symptomatology, the technique can be improved. One of its main limitations is that the parameters are fixed, and the stimulation is provided uninterruptedly, not taking into account any fluctuation in the patients state. A closed-loop system which provides stimulation by demand would adjust the stimulation to the variations in the state of the patient, stimulating only when it is necessary. It would not only perform a more intelligent stimulation, capable of adapting to the changes in real time, but also extending the devices battery life, thereby avoiding surgical interventions. In this work we design a tool that learns to recognize the principal symptom of Parkinsons disease and particularly the tremor. The goal of the designed system is to detect the moments the patient is suffering from a tremor episode and consequently to decide whether stimulation is needed or not. For that, local field potentials were recorded in the subthalamic nucleus of ten Parkinsonian patients, who were diagnosed with tremor-dominant Parkinsons disease and who underwent surgery for the implantation of a neurostimulator. Electromyographic activity in the forearm was simultaneously recorded, and the relation between both signals was evaluated using two different synchronization measures. The results of evaluating the synchronization indexes on each moment represent the inputs to the designed system. Finally, a fuzzy inference system was applied with the goal of identifying tremor episodes. Results are favourable, reaching accuracies of higher 98.7% in 70% of the patients.

Indoor communications networks realized through hybrid free-space optical and Wi-Fi links

NASA Astrophysics Data System (ADS)

Liverman, Spencer; Wang, Qiwei; Chu, Yu-Chung; Borah, Anindita; Wang, Songtao; Natarajan, Arun; Nguyen, Thinh; Wang, Alan X.

2018-01-01

Recently, free-space optical (FSO) networks have been investigated as a potential replacement for traditional WiFi networks due to their large bandwidth potentials. However, FSO networks often suffer from a lack of mobility. We present a hybrid free-space optical and radio frequency (RF) system that we have named WiFO, which seamlessly integrates free-space optical links with pre-existing WiFi networks. The free-space optical link in this system utilizes infrared LEDs operating at a wavelength of 850nm and is capable of transmitting 50Mbps over a three-meter distance. In this hybrid system, optical transmitters are embedded periodically throughout the ceiling of a workspace. Each transmitter directs an optical signal downward in a diffuse light cone, establishing a line of sight optical link. Line of sight communications links have an intrinsic physical layer of security due to the fact that a user must be directly in the path of transmission to access the link; however, this feature also poses a challenge for mobility. In our system, if the free-space optical link is interrupted, a control algorithm redirects traffic over a pre-existing WiFi link ensuring uninterrupted transmissions. After data packets are received, acknowledgments are sent back to a central access point via a WiFi link. As the demand for wireless bandwidth continues to increase exponentially, utilizing the unregulated bandwidth contained within optical spectrum will become necessary. Our fully functional hybrid free-space optical and WiFi prototype system takes full advantage of the untapped bandwidth potential in the optical spectrum, while also maintaining the mobility inherent in WiFi networks.

Secure real-time wireless video streaming in the aeronautical telecommunications network

NASA Astrophysics Data System (ADS)

Czernik, Pawel; Olszyna, Jakub

2010-09-01

As Air Traffic Control Systems move from a voice only environment to one in which clearances are issued via data link, there is a risk that an unauthorized entity may attempt to masquerade as either the pilot or controller. In order to protect against this and related attacks, air-ground communications must be secured. The challenge is to add security in an environment in which bandwidth is limited. The Aeronautical Telecommunications Network (ATN) is an enabling digital network communications technology that addresses capacity and efficiency issues associated with current aeronautical voice communication systems. Equally important, the ATN facilitates migration to free flight, where direct computer-to-computer communication will automate air traffic management, minimize controller and pilot workload, and improve overall aircraft routing efficiency. Protecting ATN communications is critical since safety-of-flight is seriously affected if an unauthorized entity, a hacker for example, is able to penetrate an otherwise reliable communications system and accidentally or maliciously introduce erroneous information that jeopardizes the overall safety and integrity of a given airspace. However, an ATN security implementation must address the challenges associated with aircraft mobility, limited bandwidth communication channels, and uninterrupted operation across organizational and geopolitical boundaries. This paper provides a brief overview of the ATN, the ATN security concept, and begins a basic introduction to the relevant security concepts of security threats, security services and security mechanisms. Security mechanisms are further examined by presenting the fundamental building blocks of symmetric encipherment, asymmetric encipherment, and hash functions. The second part of this paper presents the project of cryptographiclly secure wireless communication between Unmanned Aerial Vehicles (UAV) and the ground station in the ATM system, based on the ARM9 processor development kid and Embedded Linux operation system.

Spontaneous motor rhythms of the back and legs in a patient with a complete spinal cord transection.

PubMed

Nadeau, Sylvie; Jacquemin, Géraldine; Fournier, Christine; Lamarre, Yves; Rossignol, Serge

2010-05-01

Spontaneous activity originating from the spinal cord has been sporadically reported in humans. Investigation of such rhythmic activity of the trunk and legs in a 49-year-old male patient who had a complete severance of the spinal cord at the fifth thoracic vertebra. A multichannel electromyography (EMG) study was performed together with kinematics measurements obtained from an Optotrak system. Episodes of rhythmic trunk and lower limb movements started 6 to 7 years after the spinal lesion, recurred at 2 to 3 month intervals, and continued uninterrupted for 2 to 3 days despite continuous delivery of intrathecal baclofen. Several muscles discharged more or less synchronously on both sides but others clearly alternated, for instance, between hip flexors and knee or ankle extensors. Sensory stimuli (hip repositioning or skin pinch) altered significantly the baseline rhythm of about 1 Hz. The patient had both hips injected with corticosteroids and was free of these episodic rhythmic crises for more than 6 months. The rhythmic activity observed in the patient appeared related to the activation of a spinal pattern generator akin to what has been described in most animal species after complete spinal lesions.

Does reading in shallow L1 orthography slow attrition of language-specific morphological structures?

PubMed

Zaretsky, Elena; Bar-Shalom, Eva G

2010-01-01

This study looks at the relationship between L1 (Russian) attrition and L1 reading ability in Russian-English-speaking bilingual children. Ten Russian-English bilingual children and 10 adults participated in this study. Nine out of 10 children participants were born in the US and used L1 as their primary language of interaction within the family, but the intensity and the length of uninterrupted L1 exposure differed for each child. All participants were tested on perception (grammaticality judgement) and production (narrative) tasks to assess their sensitivity to and retention of the morphosyntactic structure of L1. All children showed some attrition of grammatical morphemes, specifically in the Russian systems of declension and conjugation; however, the degree of attrition correlated with reading ability in L1, i.e. children with L1 reading skills showed a lesser degree of attrition for some language-specific morphosyntactic structures. This finding shows interdependence of oral and reading skills and points to the role reading in language with shallow orthography may play in preservation of L1 grammatical structures in oral language. The implications for the clinical applications are also discussed.

Evolutionary conservation and neuronal mechanisms of auditory perceptual restoration.

PubMed

Petkov, Christopher I; Sutter, Mitchell L

2011-01-01

Auditory perceptual 'restoration' occurs when the auditory system restores an occluded or masked sound of interest. Behavioral work on auditory restoration in humans began over 50 years ago using it to model a noisy environmental scene with competing sounds. It has become clear that not only humans experience auditory restoration: restoration has been broadly conserved in many species. Behavioral studies in humans and animals provide a necessary foundation to link the insights being obtained from human EEG and fMRI to those from animal neurophysiology. The aggregate of data resulting from multiple approaches across species has begun to clarify the neuronal bases of auditory restoration. Different types of neural responses supporting restoration have been found, supportive of multiple mechanisms working within a species. Yet a general principle has emerged that responses correlated with restoration mimic the response that would have been given to the uninterrupted sound of interest. Using the same technology to study different species will help us to better harness animal models of 'auditory scene analysis' to clarify the conserved neural mechanisms shaping the perceptual organization of sound and to advance strategies to improve hearing in natural environmental settings. © 2010 Elsevier B.V. All rights reserved.

Controlling autonomous underwater floating platforms using bacterial fermentation.

PubMed

Biffinger, Justin C; Fitzgerald, Lisa A; Howard, Erinn C; Petersen, Emily R; Fulmer, Preston A; Wu, Peter K; Ringeisen, Bradley R

2013-01-01

Biogenic gas has a wide range of energy applications from being used as a source for crude bio-oil components to direct ignition for heating. The current study describes the use of biogenic gases from Clostridium acetobutylicum for a new application-renewable ballast regeneration for autonomous underwater devices. Uninterrupted (continuous) and blocked flow (pressurization) experiments were performed to determine the overall biogas composition and total volume generated from a semirigid gelatinous matrix. For stopped flow experiments, C. acetobutylicum generated a maximum pressure of 55 psi over 48 h composed of 60 % hydrogen gas when inoculated in a 5 % agar (w/v) support with 5 % glucose (w/v) in the matrix. Typical pressures over 24 h at 318 K ranged from 10 to 33 psi. These blocked flow experiments show for the first time the use of microbial gas production as a way to repressurize gas cylinders. Continuous flow experiments successfully demonstrated how to deliver biogas to an open ballast control configuration for deployable underwater platforms. This study is a starting point for engineering and microbiology investigations of biogas which will advance the integration of biology within autonomous systems.

Synchronous Environmental and Cultural Change in the Emergence of Agricultural Economies 10,000 Years Ago in the Levant.

PubMed

Borrell, Ferran; Junno, Aripekka; Barceló, Joan Antón

2015-01-01

The commonly held belief that the emergence and establishment of farming communities in the Levant was a smooth socio-economic continuum during the Pre-Pottery Neolithic (ca. 12,000-9,000 cal BP) with only rare minor disruptions is challenged by recently obtained evidence from this region. Using a database of archaeological radiocarbon dates and diagnostic material culture records from a series of key sites in the northern Levant we show that the hitherto apparent long-term continuity interpreted as the origins and consolidation of agricultural systems was not linear and uninterrupted. A major cultural discontinuity is observed in the archaeological record around 10,000 cal BP in synchrony with a Holocene Rapid Climate Change (RCC), a short period of climatic instability recorded in the Northern Hemisphere. This study demonstrates the interconnectedness of the first agricultural economies and the ecosystems they inhabited, and emphasizes the complex nature of human responses to environmental change during the Neolithic period in the Levant. Moreover, it provides a new environmental-cultural scenario that needs to be incorporated in the models reconstructing both the establishment of agricultural economy in southwestern Asia and the impact of environmental changes on human populations.

Integrative endeavor for renaissance in Ayurveda

PubMed Central

Raut, Ashwinikumar A.

2011-01-01

Currently western medicine has assumed the central position in mainstream global healthcare. Openness to learn from contemporary disciplines of basic sciences, application of modern technology and further adoption of the evidence-based approach has helped western medicine gain its currently acknowledged position as mainstream modern medicine. Modern medicine has further developed forms of integrative medicine by developing interfaces with other systems of medicine, including traditional, complementary and alternative medicine. However, these developments do not seem to address all the problems facing global health care caused by overemphasis on pharmaco-therapeutic drug developments. On the other hand, Ayurveda which is founded on genuine fundamentals, has the longest uninterrupted tradition of healthcare practice, and its holistic approach to healthcare management emphasizes disease prevention and health promotion; if it opens up to incorporate emerging new knowledge into mainstream Ayurveda, and maintains fidelity to Ayurveda fundamentals, it will certainly provide a broad-based opportunity to address the majority of the problems that have emerged from global healthcare requirements. To bring these solutions to bear, however, it will be necessary to progress from the present “utilitarian ethos” to a “unifying ethos” for realization of medical integration. PMID:21731380

Synchronous Environmental and Cultural Change in the Emergence of Agricultural Economies 10,000 Years Ago in the Levant

PubMed Central

Borrell, Ferran; Junno, Aripekka; Barceló, Joan Antón

2015-01-01

The commonly held belief that the emergence and establishment of farming communities in the Levant was a smooth socio-economic continuum during the Pre-Pottery Neolithic (ca. 12,000-9,000 cal BP) with only rare minor disruptions is challenged by recently obtained evidence from this region. Using a database of archaeological radiocarbon dates and diagnostic material culture records from a series of key sites in the northern Levant we show that the hitherto apparent long-term continuity interpreted as the origins and consolidation of agricultural systems was not linear and uninterrupted. A major cultural discontinuity is observed in the archaeological record around 10,000 cal BP in synchrony with a Holocene Rapid Climate Change (RCC), a short period of climatic instability recorded in the Northern Hemisphere. This study demonstrates the interconnectedness of the first agricultural economies and the ecosystems they inhabited, and emphasizes the complex nature of human responses to environmental change during the Neolithic period in the Levant. Moreover, it provides a new environmental-cultural scenario that needs to be incorporated in the models reconstructing both the establishment of agricultural economy in southwestern Asia and the impact of environmental changes on human populations. PMID:26241310

Systems and methods for an integrated electrical sub-system powered by wind energy

DOEpatents

Liu, Yan [Ballston Lake, NY; Garces, Luis Jose [Niskayuna, NY

2008-06-24

Various embodiments relate to systems and methods related to an integrated electrically-powered sub-system and wind power system including a wind power source, an electrically-powered sub-system coupled to and at least partially powered by the wind power source, the electrically-powered sub-system being coupled to the wind power source through power converters, and a supervisory controller coupled to the wind power source and the electrically-powered sub-system to monitor and manage the integrated electrically-powered sub-system and wind power system.

The Chandra Source Catalog: Source Variability

NASA Astrophysics Data System (ADS)

Nowak, Michael; Rots, A. H.; McCollough, M. L.; Primini, F. A.; Glotfelty, K. J.; Bonaventura, N. R.; Chen, J. C.; Davis, J. E.; Doe, S. M.; Evans, J. D.; Fabbiano, G.; Galle, E.; Gibbs, D. G.; Grier, J. D.; Hain, R.; Hall, D. M.; Harbo, P. N.; He, X.; Houck, J. C.; Karovska, M.; Lauer, J.; McDowell, J. C.; Miller, J. B.; Mitschang, A. W.; Morgan, D. L.; Nichols, J. S.; Plummer, D. A.; Refsdal, B. L.; Siemiginowska, A. L.; Sundheim, B. A.; Tibbetts, M. S.; Van Stone, D. W.; Winkelman, S. L.; Zografou, P.

2009-01-01

The Chandra Source Catalog (CSC) contains fields of view that have been studied with individual, uninterrupted observations that span integration times ranging from 1 ksec to 160 ksec, and a large number of which have received (multiple) repeat observations days to years later. The CSC thus offers an unprecedented look at the variability of the X-ray sky over a broad range of time scales, and across a wide diversity of variable X-ray sources: stars in the local galactic neighborhood, galactic and extragalactic X-ray binaries, Active Galactic Nuclei, etc. Here we describe the methods used to identify and quantify source variability within a single observation, and the methods used to assess the variability of a source when detected in multiple, individual observations. Three tests are used to detect source variability within a single observation: the Kolmogorov-Smirnov test and its variant, the Kuiper test, and a Bayesian approach originally suggested by Gregory and Loredo. The latter test not only provides an indicator of variability, but is also used to create a best estimate of the variable lightcurve shape. We assess the performance of these tests via simulation of statistically stationary, variable processes with arbitrary input power spectral densities (here we concentrate on results of red noise simulations) at variety of mean count rates and fractional root mean square variabilities relevant to CSC sources. We also assess the false positive rate via simulations of constant sources whose sole source of fluctuation is Poisson noise. We compare these simulations to a preliminary assessment of the variability found in real CSC sources, and estimate the variability sensitivities of the CSC.

The Chandra Source Catalog: Source Variability

NASA Astrophysics Data System (ADS)

Nowak, Michael; Rots, A. H.; McCollough, M. L.; Primini, F. A.; Glotfelty, K. J.; Bonaventura, N. R.; Chen, J. C.; Davis, J. E.; Doe, S. M.; Evans, J. D.; Evans, I.; Fabbiano, G.; Galle, E. C.; Gibbs, D. G., II; Grier, J. D.; Hain, R.; Hall, D. M.; Harbo, P. N.; He, X.; Houck, J. C.; Karovska, M.; Lauer, J.; McDowell, J. C.; Miller, J. B.; Mitschang, A. W.; Morgan, D. L.; Nichols, J. S.; Plummer, D. A.; Refsdal, B. L.; Siemiginowska, A. L.; Sundheim, B. A.; Tibbetts, M. S.; van Stone, D. W.; Winkelman, S. L.; Zografou, P.

2009-09-01

The Chandra Source Catalog (CSC) contains fields of view that have been studied with individual, uninterrupted observations that span integration times ranging from 1 ksec to 160 ksec, and a large number of which have received (multiple) repeat observations days to years later. The CSC thus offers an unprecedented look at the variability of the X-ray sky over a broad range of time scales, and across a wide diversity of variable X-ray sources: stars in the local galactic neighborhood, galactic and extragalactic X-ray binaries, Active Galactic Nuclei, etc. Here we describe the methods used to identify and quantify source variability within a single observation, and the methods used to assess the variability of a source when detected in multiple, individual observations. Three tests are used to detect source variability within a single observation: the Kolmogorov-Smirnov test and its variant, the Kuiper test, and a Bayesian approach originally suggested by Gregory and Loredo. The latter test not only provides an indicator of variability, but is also used to create a best estimate of the variable lightcurve shape. We assess the performance of these tests via simulation of statistically stationary, variable processes with arbitrary input power spectral densities (here we concentrate on results of red noise simulations) at variety of mean count rates and fractional root mean square variabilities relevant to CSC sources. We also assess the false positive rate via simulations of constant sources whose sole source of fluctuation is Poisson noise. We compare these simulations to an assessment of the variability found in real CSC sources, and estimate the variability sensitivities of the CSC.

Is slack an intrinsic seizure terminator?

PubMed

Igelström, Kajsa M

2013-06-01

Understanding how epileptic seizures are initiated and propagated across large brain networks is difficult, but an even greater mystery is what makes them stop. Failure of spontaneous seizure termination leads to status epilepticus-a state of uninterrupted seizure activity that can cause death or permanent brain damage. Global factors, like changes in neuromodulators and ion concentrations, are likely to play major roles in spontaneous seizure cessation, but individual neurons also have intrinsic active ion currents that may contribute. The recently discovered gene Slack encodes a sodium-activated potassium channel that mediates a major proportion of the outward current in many neurons. Although given little attention, the current flowing through this channel may have properties consistent with a role in seizure termination.

Bottom-up, Robust Graphene Ribbon Electronics in All-Carbon Molecular Junctions.

PubMed

Supur, Mustafa; Van Dyck, Colin; Bergren, Adam J; McCreery, Richard L

2018-02-21

Large-area molecular electronic junctions consisting of 5-carbon wide graphene ribbons (GR) with lengths of 2-12 nm between carbon electrodes were fabricated by electrochemical reduction of diazotized 1,8-diaminonaphthalene. Their conductance greatly exceeds that observed for other molecular junctions of similar thicknesses, by a factor of >1 × 10 4 compared to polyphenylenes and >1 × 10 7 compared to alkane chains. The remarkable increase of conductance of the GR nanolayer results from (i) uninterrupted planarity of fused-arene structure affording extensive π-electron delocalization and (ii) enhanced electronic coupling of molecular layer with the carbon bottom contact by two-point covalent bonding, in agreement with DFT-based simulations.

Recurrent arterial thrombosis associated with the antithrombin basel variant and elevated lipoprotein(a) plasma level in an adolescent patient.

PubMed

Szilágyi, Szabolcs; Péter, Andrea; Magyar, Mária Tünde; Balogh, Sándor; Bereczky, Zsuzsanna

2012-05-01

Both myocardial infarction and ischemic stroke are rare in the young. Yet a 15-year-old male patient suffered a myocardial infarction and later an ischemic stroke despite uninterrupted antiplatelet therapy. His medical history involved the surgical correction of an incomplete atrioventricular canal defect at the age of 13 years. No cardiovascular risk factors other than elevated lipoprotein(a) level could be identified. His antithrombin (AT) activity was decreased and DNA sequence analysis revealed heterozygosity for AT Basel (p.Pro41Leu), a variant with impaired heparin binding. This report supports a possible additional pathophysiological role for AT Basel and elevated lipoprotein(a) level in arterial thrombogenesis.

People's preference patterns for gains/losses in multiple time period situations.

PubMed

Chang, Shin-Shin; Chang, Jung-Hua

2013-10-01

Little research to date has been devoted to investigating whether people treat time differently from money when facing multiple gains or losses. This study tested the hypothesis that because time is characterized by perishability, fixed supply, and infungibility, people with strong motivation to obtain a long period of uninterrupted discretionary time would strive to trim the time needed for non-discretionary activities or to combine several non-discretionary activities. As a result, people prefer integration over segregation of multiple time losses or gains, which is not consistent with the prediction based on hedonic editing theory or the renewable resource model. This proposition is supported by results from four experiments.

Effects of polycrystallinity in nano patterning by ion-beam sputtering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yoon, Sun Mi; Kim, J.-S., E-mail: jskim@sm.ac.kr; Yoon, D.

Employing graphites with distinctly different mean grain sizes, we study the effects of polycrystallinity on the pattern formation by ion-beam sputtering. The grains influence the growth of the ripples in a highly anisotropic fashion; both the mean uninterrupted ripple length along the ridges and the surface width depend on the mean size of the grains, which is attributed to the large sputter yield at the grain boundary compared with that on the terrace. In contrast, the ripple wavelength does not depend on the mean size of the grains, indicating that the mass transport across the grain boundaries should efficiently proceedmore » by both thermal diffusion and ion-induced processes.« less

Electro-optic guided-mode resonance tuning suppressible by optically induced screening in a vertically coupled hybrid GaN/Si microring resonator

NASA Astrophysics Data System (ADS)

Thubthimthong, B.; Sasaki, T.; Hane, K.

2018-02-01

GaN as a nanophotonic material has gained much attention in recent years. Using the hybrid GaN/Si platform, we report the electro-optic tuning of guided-mode resonance in a vertically coupled hybrid GaN/Si microring resonator operating in the 1.5 μm window with up to a 6 dB extinction ratio and a 1.5 MHz modulation frequency (test equipment limit). The electro-optic tuning could be optically suppressed by electron-hole-originated screening induced by an ultraviolet excitation at 325 nm. Our work may benefit in externally intervenable optical interconnects for uninterrupted secure photonic networks.

Antiretroviral drug supply challenges in the era of scaling up ART in Malawi.

PubMed

Schouten, Erik J; Jahn, Andreas; Ben-Smith, Anne; Makombe, Simon D; Harries, Anthony D; Aboagye-Nyame, Francis; Chimbwandira, Frank

2011-07-06

The number of people receiving antiretroviral treatment (ART) has increased considerably in recent years and is expected to continue to grow in the coming years. A major challenge is to maintain uninterrupted supplies of antiretroviral (ARV) drugs and prevent stock outs. This article discusses issues around the management of ARVs and prevention of stock outs in Malawi, a low-income country with a high HIV/AIDS burden, and a weak procurement and supply chain management system. This system for ARVs, paid for by the Global Fund to Fight AIDS, Tuberculosis and Malaria, and bypassing the government Central Medical Stores, is in place, using the United Nations Children's Fund's (UNICEF's) procurement services. The system, managed by a handful of people who spend limited time on supply management, is characterized by a centrally coordinated quantification based on verified data from all national ART clinics, parallel procurement through UNICEF, and direct distribution to ART clinics. The model worked well in the first years of the ART programme with a single first-line ARV regimen, but with more regimens becoming available (e.g., alternative first-line, second-line and paediatric regimens), it has become more difficult to administer. Managing supplies through a parallel system has the advantage that weaknesses in the national system have limited influence on the ARV procurement and supply chain management system. However, as the current system operates without a central warehouse and national buffer stock capacity, it diminishes the ability to prevent ARV stock outs. The process of ordering ARVs, from the time that estimates are made to the arrival of supplies in health facilities, takes approximately one year. Addressing the challenges involved in maintaining ARVs through an efficient procurement and supply chain management system that prevents ARV stock outs through the establishment of a dedicated procurement team, a central warehouse and/or national buffer stock is a priority.

Landmark-based robust navigation for tactical UGV control in GPS-denied communication-degraded environments

NASA Astrophysics Data System (ADS)

Endo, Yoichiro; Balloch, Jonathan C.; Grushin, Alexander; Lee, Mun Wai; Handelman, David

2016-05-01

Control of current tactical unmanned ground vehicles (UGVs) is typically accomplished through two alternative modes of operation, namely, low-level manual control using joysticks and high-level planning-based autonomous control. Each mode has its own merits as well as inherent mission-critical disadvantages. Low-level joystick control is vulnerable to communication delay and degradation, and high-level navigation often depends on uninterrupted GPS signals and/or energy-emissive (non-stealth) range sensors such as LIDAR for localization and mapping. To address these problems, we have developed a mid-level control technique where the operator semi-autonomously drives the robot relative to visible landmarks that are commonly recognizable by both humans and machines such as closed contours and structured lines. Our novel solution relies solely on optical and non-optical passive sensors and can be operated under GPS-denied, communication-degraded environments. To control the robot using these landmarks, we developed an interactive graphical user interface (GUI) that allows the operator to select landmarks in the robot's view and direct the robot relative to one or more of the landmarks. The integrated UGV control system was evaluated based on its ability to robustly navigate through indoor environments. The system was successfully field tested with QinetiQ North America's TALON UGV and Tactical Robot Controller (TRC), a ruggedized operator control unit (OCU). We found that the proposed system is indeed robust against communication delay and degradation, and provides the operator with steady and reliable control of the UGV in realistic tactical scenarios.

Car Travel-Related Thrombosis: Fact or Fiction?

PubMed

Lippi, Giuseppe; Favaloro, Emmanuel J

2018-06-01

The condition sometimes referred to as "economy class syndrome," and also known as "traveler's thrombosis," is a distinctive pathological condition characterized by occurrence of venous thromboembolism (VTE) in a patient who has recently experienced a long journey (i.e., ≥ 4 h). Typically, the identified travel is by airplane, but travel with other vehicles, such as trains, trucks, buses, or cars, could potentially qualify as contributing to VTE events. Although the enhanced risk of VTE after long haul flights is now widely acknowledged, albeit potentially overhyped, the risk of venous thrombosis after prolonged travel by other modes of transport, in particular, by cars, is less well appreciated. Current evidence, collected from some epidemiological studies, suggests that if any risk of VTE can be attributed to prolonged and uninterrupted car travels, and we give moderate credibility to such an association, the risk may be similar to that already proven for long haul flights. The risk is especially high in individuals undergoing uninterrupted car journeys lasting 4 hours or longer, in vehicles with a narrow seat-pitch, and in particularly would affect those with pre-existing acquired or inherited prothrombotic conditions. The putative biological mechanisms basically entail venous stasis and edema, which are often compounded by a certain degree of hypercoagulability. When these factors are combined with preexistent prothrombotic conditions, the risk may be substantially magnified. In this perspective, then, 'car thrombosis' may be regarded as a trigger rather than a risk factor for venous thrombosis. Although the current evidence is certainly not solid enough to endorse the use of general chemical prophylaxis for lowering the risk of car-related VTE, a set of possible precautionary measures, with no or very little side effects, may be suggested before planning prolonged car travels, especially for at risk individuals. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Estimates of the Continuously Publishing Core in the Scientific Workforce

PubMed Central

Ioannidis, John P. A.; Boyack, Kevin W.; Klavans, Richard

2014-01-01

Background The ability of a scientist to maintain a continuous stream of publication may be important, because research requires continuity of effort. However, there is no data on what proportion of scientists manages to publish each and every year over long periods of time. Methodology/Principal Findings Using the entire Scopus database, we estimated that there are 15,153,100 publishing scientists (distinct author identifiers) in the period 1996–2011. However, only 150,608 (<1%) of them have published something in each and every year in this 16-year period (uninterrupted, continuous presence [UCP] in the literature). This small core of scientists with UCP are far more cited than others, and they account for 41.7% of all papers in the same period and 87.1% of all papers with >1000 citations in the same period. Skipping even a single year substantially affected the average citation impact. We also studied the birth and death dynamics of membership in this influential UCP core, by imputing and estimating UCP-births and UCP-deaths. We estimated that 16,877 scientists would qualify for UCP-birth in 1997 (no publication in 1996, UCP in 1997–2012) and 9,673 scientists had their UCP-death in 2010. The relative representation of authors with UCP was enriched in Medical Research, in the academic sector and in Europe/North America, while the relative representation of authors without UCP was enriched in the Social Sciences and Humanities, in industry, and in other continents. Conclusions The proportion of the scientific workforce that maintains a continuous uninterrupted stream of publications each and every year over many years is very limited, but it accounts for the lion’s share of researchers with high citation impact. This finding may have implications for the structure, stability and vulnerability of the scientific workforce. PMID:25007173

Text4baby program: an opportunity to reach underserved pregnant and postpartum women?

PubMed

Gazmararian, Julie A; Elon, Lisa; Yang, Baiyu; Graham, Megan; Parker, Ruth

2014-01-01

Text4baby was launched in 2010 to promote healthy pregnancies and babies by the use of text messaging. The primary objective of this study was to assess factors related to the enrollment process and reception of text4baby. A prospective cohort study was conducted in two Women, Infant and Children clinics in Atlanta (April 2010-July 2011). Randomly selected pregnant and postpartum women (n = 468) were queried on cell phone use and instructed on text4baby enrollment. Self-enrollment issues were assessed at one-week follow-up (n = 351, 75.0 %), and message reception and reading patterns at two-month follow-up (n = 209, 44.7 %). Forty-two percent of the women had some college education and 82 % had household income <=$20,000. About half attempted text4baby self-enrollment (162/351), with enrollment success more likely among women with more education (80 % with some college vs. 62 % with less education), with household income above $10,000 (61 % < $10,000 vs. 83 % $10,001-$20,000 and 76 % > $20,000), and among women living in smaller households (77 % 1-3 members vs. 58 % > 3 members) (all p < 0.001). Among the 209 participants in the final follow-up contact, >90 % reported uninterrupted reception and regular reading of messages, and 88 % planned to continue using text4baby. Results also suggested that respondents who were younger (<26 year), less educated and had lower health literacy skills were more likely to have interrupted messages. Despite substantial interest in the text4baby program in an underserved population, innovative ways to help women with significant disadvantages enroll and receive uninterrupted messages are needed.

Role of dominant versus non-dominant hand position during uninterrupted chest compression CPR by novice rescuers: a randomized double-blind crossover study.

PubMed

Nikandish, Reza; Shahbazi, Sharbanoo; Golabi, Sedigheh; Beygi, Najimeh

2008-02-01

Previous research has suggested improved quality of chest compressions when the dominant hand was in contact with the sternum. However, the study was in health care professionals and during conventional chest compression-ventilation CPR. The aim of this study was to test the hypothesis, in null form, that the quality of external chest compressions (ECC) in novice rescuers during 5min of uninterrupted chest compression CPR (UCC-CPR) is independent of the hand in contact with the sternum. Confirmation of the hypothesis would allow the use of either hand by the novice rescuers during UCC-CPR. Fifty-nine first year public heath students participated in this randomised double-blind crossover study. After completion of a standard adult BLS course, they performed single rescuer adult UCC-CPR for 5 min on a recording Resusci Anne. One week later they changed the hand of contact with the sternum while performing ECC. The quality of ECC was recorded by the skill meter for the dominant and non-dominant hand during 5 min ECC. The total number of correct chest compressions in the dominant hand group (DH), mean 183+/-152, was not statistically different from the non-dominant hand group (NH), mean 152+/-135 (P=0.09). The number of ECC with inadequate depth in the DH group, mean 197+/-174 and NH group, mean 196+/-173 were comparable (P=0.1). The incidence of ECC exceeding the recommended depth in the DH group, mean 51+/-110 and NH group, mean 32+/-75 were comparable (P=0.1). Although there is a trend to increased incidence of correct chest compressions with positioning the dominant hand in contact with the sternum, it does not reach statistical significance during UCC-CPR by the novice rescuers for 5 min.

Risk of Hemorrhage Attributed to Underlying Chronic Diseases and Uninterrupted Aspirin Therapy of Patients Undergoing Minor Oral Surgical Procedures: A Retrospective Cohort Study.

PubMed

Rojanaworarit, Chanapong; Limsawan, Soontaree

2017-01-01

This study aimed to estimate the risk of bleeding following minor oral surgical procedures and uninterrupted aspirin therapy in high-risk patients or patients with existing chronic diseases compared to patients who did not use aspirin during minor oral surgery at a public hospital. This retrospective cohort study analyzed the data of 2912 patients, aged 20 years or older, who underwent 5251 minor oral surgical procedures at a district hospital in Thailand. The aspirin group was comprised of patients continuing aspirin therapy during oral surgery. The non-aspirin group (reference) included all those who did not use aspirin during surgery. Immediate and late-onset bleeding was evaluated in each procedure. The risk ratio of bleeding was estimated using a multilevel Poisson regression. The overall cumulative incidence of immediate bleeding was 1.3% of total procedures. No late-onset bleeding was found. A significantly greater incidence of bleeding was found in the aspirin group (5.8% of procedures, p<0.001). After adjusting for covariates, a multilevel Poisson regression model estimated that the bleeding risk in the aspirin group was 4.5 times higher than that of the non-aspirin group (95% confidence interval, 2.0 to 10.0; p<0.001). However, all bleeding events were controlled by simple hemostatic measures. High-risk patients or patients with existing chronic diseases who continued aspirin therapy following minor oral surgery were at a higher risk of hemorrhage than general patients who had not used aspirin. Nonetheless, bleeding complications were not life-threatening and could be promptly managed by simple hemostatic measures. The procedures could therefore be provided with an awareness of increased bleeding risk, prepared hemostatic measures, and postoperative monitoring, without the need for discontinuing aspirin, which could lead to more serious complications.

Artificial intelligence: Neural network model as the multidisciplinary team member in clinical decision support to avoid medical mistakes.

PubMed

Buzaev, Igor Vyacheslavovich; Plechev, Vladimir Vyacheslavovich; Nikolaeva, Irina Evgenievna; Galimova, Rezida Maratovna

2016-09-01

The continuous uninterrupted feedback system is the essential part of any well-organized system. We propose aLYNX concept that is a possibility to use an artificial intelligence algorithm or a neural network model in decision-making system so as to avoid possible mistakes and to remind the doctors to review tactics once more in selected cases. aLYNX system includes: registry with significant factors, decisions and results; machine learning process based on this registry data; the use of the machine learning results as the adviser. We show a possibility to build a computer adviser with a neural network model for making a choice between coronary aortic bypass surgery (CABG) and percutaneous coronary intervention (PCI) in order to achieve a higher 5-year survival rate in patients with angina based on the experience of 5107 patients. The neural network was trained by 4679 patients who achieved 5-year survival. Among them, 2390 patients underwent PCI and 2289 CABG. After training, the correlation coefficient ( r ) of the network was 0.74 for training, 0.67 for validation, 0.71 for test and 0.73 for total. Simulation of the neural network function has been performed after training in the two groups of patients with known 5-year outcome. The disagreement rate was significantly higher in the dead patient group than that in the survivor group between neural network model and heart team [16.8% (787/4679) vs. 20.3% (87/428), P  = 0.065)]. The study shows the possibility to build a computer adviser with a neural network model for making a choice between CABG and PCI in order to achieve a higher 5-year survival rate in patients with angina.

Comparison of Frequencies and Rotational Splittings of Solar Acoustic Modes of Low Angular Degree from Simultaneous MDI and GOLF Observations

NASA Astrophysics Data System (ADS)

Bertello, L.; Henney, C. J.; Ulrich, R. K.; Varadi, F.; Kosovichev, A. G.; Scherrer, P. H.; Cortés, T. Roca; Thiery, S.; Boumier, P.; Gabriel, A. H.; Turck-Chièze, S.

2000-06-01

During the years 1996 through 1998 the Michelson Doppler Imager (MDI) and the Global Oscillations at Low Frequency (GOLF) experiments on the Solar and Heliospheric Observatory (SOHO) mission have provided unique and nearly uninterrupted sequences of helioseismic observations. This paper describes the analysis carried out on power spectra from 759 days of calibrated disk-averaged velocity signals provided by these two experiments. The period investigated in this work is from 1996 May 25 to 1998 June 22. We report the results of frequency determination of low-degree (l<=3) acoustic modes in the frequency range between 1.4 mHz and 3.7 mHz. Rotational splittings are also measured for nonradial modes up to 3.0 mHz. The power spectrum estimation of the signals is performed using classical Fourier analysis and the line-profile parameters of the modes are determined by means of a maximum likelihood method. All parameters have been estimated using both symmetrical and asymmetrical line profile-fitting formula. The line asymmetry parameter of all modes with frequency higher than 2.0 mHz is systematically negative and independent of l. This result is consistent with the fact that both MDI and GOLF data sets investigated in this paper are predominantly velocity signals, in agreement with previous results. A comparison of the results between the symmetric and asymmetric fits shows that there is a systematic shift in the frequencies for modes above 2.0 mHz. Below this frequency, the line width of the modes is very small and the time base of the data does not provide enough statistics to reveal an asymmetry. In general, the results show that frequency and rotational splitting values obtained from both the MDI and GOLF signals are in excellent agreement, and no significant differences exist between the two data sets within the accuracy of the measurements. Our results are consistent with a uniform rotation of the solar core at the rate of about 435 nHz and show only very small deviations of the core structure from the standard solar model.

Short-Term Variability and Power Spectral Density Analysis of the Radio-Loud Active Galactic Nucleus 3C 390.3

NASA Astrophysics Data System (ADS)

Gliozzi, Mario; Papadakis, Iossif E.; Eracleous, Michael; Sambruna, Rita M.; Ballantyne, David R.; Braito, Valentina; Reeves, James N.

2009-09-01

We investigate the short-term variability properties and the power spectral density (PSD) of the broad-line radio galaxy (BLRG) 3C 390.3 using observations made by XMM-Newton, RXTE, and Suzaku on several occasions between 2004 October and 2006 December. The main aim of this work is to derive model-independent constraints on the origin of the X-ray emission and on the nature of the central engine in 3C 390.3. On timescales of the order of few hours, probed by uninterrupted XMM-Newton light curves, the flux of 3C 390.3 is consistent with being constant in all energy bands. On longer timescales, probed by the 2-day RXTE and Suzaku observations, the flux variability becomes significant. The latter observation confirms that the spectral variability behavior of 3C 390.3 is consistent with the spectral evolution observed in (radio-quiet) Seyfert galaxies: the spectrum softens as the source brightens. The correlated variability between soft and hard X-rays, observed during the Suzaku exposure and between the two XMM-Newton pointings, taken 1 week apart, argues against scenarios characterized by the presence of two distinct variable components in the 0.5-10 keV X-ray band. A detailed PSD analysis carried out over five decades in frequency suggests the presence of a break at T br = 43+34 -25 days at a 92% confidence level. This is the second tentative detection of a PSD break in a radio-loud, non-jet dominated active galactic nucleus (AGN), after the BLRG 3C 120, and appears to be in general agreement with the relation between T br, M BH, and L bol, followed by Seyfert galaxies. Our results indicate that the X-ray variability properties of 3C 390.3 are broadly consistent with those of radio-quiet AGN, suggesting that the X-ray emission mechanism in 3C 390.3 is similar to that of nearby Seyfert galaxies without any significant contribution from a jet component.

Experience in connecting the power generating units of thermal power plants to automatic secondary frequency regulation within the united power system of Russia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhukov, A. V.; Komarov, A. N.; Safronov, A. N.

The principles of central control of the power generating units of thermal power plants by automatic secondary frequency and active power overcurrent regulation systems, and the algorithms for interactions between automatic power control systems for the power production units in thermal power plants and centralized systems for automatic frequency and power regulation, are discussed. The order of switching the power generating units of thermal power plants over to control by a centralized system for automatic frequency and power regulation and by the Central Coordinating System for automatic frequency and power regulation is presented. The results of full-scale system tests ofmore » the control of power generating units of the Kirishskaya, Stavropol, and Perm GRES (State Regional Electric Power Plants) by the Central Coordinating System for automatic frequency and power regulation at the United Power System of Russia on September 23-25, 2008, are reported.« less

The Value of Certainty (Invited)

NASA Astrophysics Data System (ADS)

Barkstrom, B. R.

2009-12-01

It is clear that Earth science data are valued, in part, for their ability to provide some certainty about the past state of the Earth and about its probable future states. We can sharpen this notion by using seven categories of value ● Warning Service, requiring latency of three hours or less, as well as uninterrupted service ● Information Service, requiring latency less than about two weeks, as well as unterrupted service ● Process Information, requiring ability to distinguish between alternative processes ● Short-term Statistics, requiring ability to construct a reliable record of the statistics of a parameter for an interval of five years or less, e.g. crop insurance ● Mid-term Statistics, requiring ability to construct a reliable record of the statistics of a parameter for an interval of twenty-five years or less, e.g. power plant siting ● Long-term Statistics, requiring ability to construct a reliable record of the statistics of a parameter for an interval of a century or less, e.g. one hundred year flood planning ● Doomsday Statistics, requiring ability to construct a reliable statistical record that is useful for reducing the impact of `doomsday' scenarios While the first two of these categories place high value on having an uninterrupted flow of information, and the third places value on contributing to our understanding of physical processes, it is notable that the last four may be placed on a common footing by considering the ability of observations to reduce uncertainty. Quantitatively, we can often identify metrics for parameters of interest that are fairly simple. For example, ● Detection of change in the average value of a single parameter, such as global temperature ● Detection of a trend, whether linear or nonlinear, such as the trend in cloud forcing known as cloud feedback ● Detection of a change in extreme value statistics, such as flood frequency or drought severity For such quantities, we can quantify uncertainty in terms of the entropy which is calculated by creating a set of discrete bins for the value and then using error estimates to assign probabilities, pi, to each bin. The entropy, H, is simply H = ∑i pi log2(1/pi) The value of a new set of observations is the information gain, I, which is I = Hprior - Hposterior The probability distributions that appear in this calculation depend on rigorous evaluation of errors in the observations. While direct estimates of the monetary value of data that could be used in budget prioritizations may not capture the value of data to the scientific community, it appears that the information gain may be a useful start in providing a `common currency' for evaluating projects that serve very different communities. In addition, from the standpoint of governmental accounting, it appears reasonable to assume that much of the expense for scientific data become sunk costs shortly after operations begin and that the real, long-term value is created by the effort scientists expend in creating the software that interprets the data and in the effort expended in calibration and validation. These efforts are the ones that directly contribute to the information gain that provides the value of these data.

Three-dimensional culture and interaction of cancer cells and dendritic cells in an electrospun nano-submicron hybrid fibrous scaffold

PubMed Central

Kim, Tae-Eon; Kim, Chang Gun; Kim, Jin Soo; Jin, Songwan; Yoon, Sik; Bae, Hae-Rahn; Kim, Jeong-Hwa; Jeong, Young Hun; Kwak, Jong-Young

2016-01-01

An artificial three-dimensional (3D) culture system that mimics the tumor microenvironment in vitro is an essential tool for investigating the cross-talk between immune and cancer cells in tumors. In this study, we developed a 3D culture system using an electrospun poly(ε-caprolactone) (PCL) nanofibrous scaffold (NFS). A hybrid NFS containing an uninterrupted network of nano- and submicron-scale fibers (400 nm to 2 µm) was generated by deposition onto a stainless steel mesh instead of an aluminum plate. The hybrid NFS contained multiplanar pores in a 3D structure. Surface-seeded mouse CT26 colon cancer cells and bone marrow-derived dendritic cells (BM-DCs) were able to infiltrate the hybrid NFS within several hours. BM-DCs cultured on PCL nanofibers showed a baseline inactive form, and lipopolysaccharide (LPS)-activated BM-DCs showed increased expression of CD86 and major histocompatibility complex Class II. Actin and phosphorylated FAK were enriched where unstimulated and LPS-stimulated BM-DCs contacted the fibers in the 3D hybrid NFS. When BM-DCs were cocultured with mitoxantrone-treated CT26 cells in a 3D hybrid NFS, BM-DCs sprouted cytoplasm to, migrated to, synapsed with, and engulfed mitoxantrone-treated CT26 cancer cells, which were similar to the naturally occurring cross-talk between these two types of cells. The 3D hybrid NFS developed here provides a 3D structure for coculture of cancer and immune cells. PMID:27042051

Three-dimensional culture and interaction of cancer cells and dendritic cells in an electrospun nano-submicron hybrid fibrous scaffold.

PubMed

Kim, Tae-Eon; Kim, Chang Gun; Kim, Jin Soo; Jin, Songwan; Yoon, Sik; Bae, Hae-Rahn; Kim, Jeong-Hwa; Jeong, Young Hun; Kwak, Jong-Young

2016-01-01

An artificial three-dimensional (3D) culture system that mimics the tumor microenvironment in vitro is an essential tool for investigating the cross-talk between immune and cancer cells in tumors. In this study, we developed a 3D culture system using an electrospun poly(ε-caprolactone) (PCL) nanofibrous scaffold (NFS). A hybrid NFS containing an uninterrupted network of nano- and submicron-scale fibers (400 nm to 2 µm) was generated by deposition onto a stainless steel mesh instead of an aluminum plate. The hybrid NFS contained multiplanar pores in a 3D structure. Surface-seeded mouse CT26 colon cancer cells and bone marrow-derived dendritic cells (BM-DCs) were able to infiltrate the hybrid NFS within several hours. BM-DCs cultured on PCL nanofibers showed a baseline inactive form, and lipopolysaccharide (LPS)-activated BM-DCs showed increased expression of CD86 and major histocompatibility complex Class II. Actin and phosphorylated FAK were enriched where unstimulated and LPS-stimulated BM-DCs contacted the fibers in the 3D hybrid NFS. When BM-DCs were cocultured with mitoxantrone-treated CT26 cells in a 3D hybrid NFS, BM-DCs sprouted cytoplasm to, migrated to, synapsed with, and engulfed mitoxantrone-treated CT26 cancer cells, which were similar to the naturally occurring cross-talk between these two types of cells. The 3D hybrid NFS developed here provides a 3D structure for coculture of cancer and immune cells.

OTEC biofouling, corrosion, and materials study from a moored platform at Punta Tuna, Puerto Rico

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sasscer, D.S.; Tosteson, T.R.; Morgan, T.O.

1981-08-01

During the 404 days between 29 January 1980 and 10 March 1981 the Center conducted an uninterrupted biofouling test at Punta Tuna, Puerto Rico, of periodically cleaned, OTEC evaporator tubes. The fouling resistance (R/sub f), total surface carbon and nitrogen content, ATP, and the wet film thickness (WFT) were determined throughout the test. Visual observations of the fouling film were made by light sectioning and scanning microscopy, and at the end of the test, a study was made of the macrofouling of the flow system. The results of thest tests indicate that a base layer of bacteria and exudated polysaccharidesmore » enhance microbial adhesion and thereby create an environment conducive to rapid film growth. Fouling rates (dR/sub f//dt) for aluminum were generally higher than for titanium but they were linear for both materials and did not exceed 0.3(10/sup -4/)ft/sup 2/-h-/sup 0/F/Btu-day for either material during the 13-month study. Excellent correlation was found to exist between R/sub f/ and WFT which supports the hypothesis that it is the stagnant film of water entrapped by bacteria which is largely responsible for the insulating properties of the biofilm. The macrofouling study identified 61 species of benthic invertebrates representing ten phyla growing in those parts of the flow system, where flow was less than 3 fps but no macrofouling where the flow velocity significantly exceeded 3 fps.« less

Incubator-independent cell-culture perfusion platform for continuous long-term microelectrode array electrophysiology and time-lapse imaging

PubMed Central

Saalfrank, Dirk; Konduri, Anil Krishna; Latifi, Shahrzad; Habibey, Rouhollah; Golabchi, Asiyeh; Martiniuc, Aurel Vasile; Knoll, Alois; Ingebrandt, Sven; Blau, Axel

2015-01-01

Most in vitro electrophysiology studies extract information and draw conclusions from representative, temporally limited snapshot experiments. This approach bears the risk of missing decisive moments that may make a difference in our understanding of physiological events. This feasibility study presents a simple benchtop cell-culture perfusion system adapted to commercial microelectrode arrays (MEAs), multichannel electrophysiology equipment and common inverted microscopy stages for simultaneous and uninterrupted extracellular electrophysiology and time-lapse imaging at ambient CO2 levels. The concept relies on a transparent, replica-casted polydimethylsiloxane perfusion cap, gravity- or syringe-pump-driven perfusion and preconditioning of pH-buffered serum-free cell-culture medium to ambient CO2 levels at physiological temperatures. The low-cost microfluidic in vitro enabling platform, which allows us to image cultures immediately after cell plating, is easy to reproduce and is adaptable to the geometries of different cell-culture containers. It permits the continuous and simultaneous multimodal long-term acquisition or manipulation of optical and electrophysiological parameter sets, thereby considerably widening the range of experimental possibilities. Two exemplary proof-of-concept long-term MEA studies on hippocampal networks illustrate system performance. Continuous extracellular recordings over a period of up to 70 days revealed details on both sudden and gradual neural activity changes in maturing cell ensembles with large intra-day fluctuations. Correlated time-lapse imaging unveiled rather static macroscopic network architectures with previously unreported local morphological oscillations on the timescale of minutes. PMID:26543581

How good is our genome?

PubMed Central

Weill, Jean-Claude; Radman, Miroslav

2004-01-01

Our genome has evolved to perpetuate itself through the maintenance of the species via an uninterrupted chain of reproductive somas. Accordingly, evolution is not concerned with diseases occurring after the soma's reproductive stage. Following Richard Dawkins, we would like to reassert that we indeed live as disposable somas, slaves of our germline genome, but could soon start rebelling against such slavery. Cancer and its relation to the TP53 gene may offer a paradigmatic example. The observation that the latency period in cancer can be prolonged in mice by increasing the number of TP53 genes in their genome, suggests that sooner or later we will have to address the question of heritable disease avoidance via the manipulation of the human germline. PMID:15065661

Taking Research Experiences for Undergraduates Online

NASA Astrophysics Data System (ADS)

Hubenthal, Michael; Judge, Jasmeet

2013-04-01

To today's budding scientists, the notion of sharing experiences and working collaboratively with distant peers is not a novelty. Instead, this is what most young scientists expect to achieve through the Internet portals they carry in their pockets and backpacks. They have never known a world without information and communication technologies (ICT) such as laptops, mobile phones, text messaging, and the Internet. As a result, they have grown to rely on uninterrupted access to the Internet for a range of information-gathering and communication activities. Further, this generation of students has fully embraced structured online learning opportunities. For example, in 2011 more than 6.7 million U.S. students in higher education took at least one online course [Allen and Seaman, 2013].

Biogasification of community-derived biomass and solid wastes in a pilot-scale SOLCON reactor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Srivastava, V.J.; Biljetina, R.; Isaacson, H.R.

1988-01-01

The Institute of Gas Technology has developed a novel, solids- concentrating (SOLCON) bioreactor to convert a variety of individual or mixed feedstocks (biomass and wastes) to methane at higher rates and efficiencies than those obtained from conventional high-rate anaerobic digesters. The biogasification studies are being conducted in a pilot-scale experimental test unit (ETU) located in the Walt Disney World Resort Complex, Orlando, Florida. This paper describes the ETU facility, the logistics of feedstock integration, the SOLCON reactor design and operating techniques, and the results obtained during 4 years of stable, uninterrupted operation with different feedstocks. The SOLCON reactor consistently outperformedmore » the conventional stirred-tank reactor by 20% to 50%.« less

Downhole vacuum cleans up tough fishing, milling jobs

DOE Office of Scientific and Technical Information (OSTI.GOV)

LaLande, P.; Flanders, B.

1996-02-01

A unique tool developed to effect reverse circulation downhole is being used successfully in problem milling and fishing operations where conventional techniques fail to recover junk in the hole. Jointly developed by several major operators in conjunction with Baker Oil Tools, the patented Reverse Circulating Tool (RCT) acts as a downhole vacuum cleaner, catching and retaining debris circulated from the wellbore while allowing fishing, milling and washover operations to continue uninterrupted. As described in several case histories overviewed, the unique vacuuming action efficiently cleans up junk and debris in even the most difficult fishing and milling applications. Downhole operations proceedmore » normally, but without threat of damage from milled debris. Developers hold both mechanical and method patents on the RCT.« less

U.S. Geological Survey program on toxic waste--ground-water contamination; proceedings of the Third technical meeting, Pensacola, Florida, March 23-27, 1987

USGS Publications Warehouse

Franks, Bernard J.

1987-01-01

Because of the widespread distribution of creosote in the environment, an abandoned wood-treatment plant in Pensacola, Fla., was selected by the U.S. Geological Survey Office of Hazardous Waste Hydrology as one of three national research demonstration areas in order to increase our understanding of hydrologic processes affecting the distributions of contaminants in ground water. The site was selected because of its long, uninterrupted history (1902 81) of discharging wastewaters to unlined surface impoundments, availability of a preliminary data base (Troutman and others, 1984), and the high probability of useful technology transfer from an investigation of the fate of organic compounds associated with wood-preserving wastewaters in the subsurface environment.

The Beliefs, Myths, and Reality Surrounding the Word Hema (Blood) from Homer to the Present

PubMed Central

Meletis, John; Konstantopoulos, Kostas

2010-01-01

All ancient nations hinged their beliefs about hema (blood) on their religious dogmas as related to mythology or the origins of religion. The Hellenes (Greeks) especially have always known hema as the well-known red fluid of the human body. Greek scientific considerations about blood date from Homeric times. The ancient Greeks considered hema as synonymous with life. In Greek myths and historical works, one finds the first references to the uninterrupted vascular circulation of blood, the differences between venous and arterial blood, and the bone marrow as the site of blood production. The Greeks also speculated about mechanisms of blood coagulation and the use of blood transfusion to save life. PMID:21490910

Future projects in asteroseismology: the unique role of Antarctica

NASA Astrophysics Data System (ADS)

Mosser, B.; Siamois Team

Asteroseismology requires observables registered in stringent conditions: very high sensitivity, uninterrupted time series, long duration. These specifications then allow to study the details of the stellar interior structure. Space-borne and ground-based asteroseismic projects are presented and compared. With CoRoT as a precursor, then Kepler and maybe Plato, the roadmap in space appears to be precisely designed. In parallel, ground-based projects are necessary to provide different and unique information on bright stars with Doppler measurements. Dome C appears to be the ideal place for ground-based asteroseismic observations. The unequalled weather conditions yield a duty cycle comparable to space. Long time series (up to 3 months) will be possible, thanks to the long duration of the polar night.

Stagnation Temperature Recording

NASA Technical Reports Server (NTRS)

Wimmer, W

1941-01-01

The present report deals with the development of a thermometer for recording stagnation temperature in compressible mediums in turbulent flow within 1 to 2 percent error of the adiabatic temperature in the stagnation point, depending upon the speed. This was achieved by placing the junction of a thermocouple near the stagnation point of an aerodynamically beneficial body, special care being taken to assure an uninterrupted supply of fresh compressed air on the junction together with the use of metals of low thermal conductivity, thus keeping heat-transfer and heat-dissipation losses to a minimum. In other experiments the use of the plate thermometer was proved unsuitable for practical measurements by reason of its profound influence in the reading by the Reynolds number and by the direction of flow.

A Perspective on Physics in Cuba

NASA Astrophysics Data System (ADS)

Handy, Carlos R.

The author is Cuban by birth: the son of an Afro-Cuban mother and an Afro-American father. He spent the first 8 years of his life attending schools in Havana and New York City. He left Cuba in 1958 so as to gain a more uninterrupted educational experience. This led to his PhD in theoretical physics from Columbia University in 1978, followed by a post-doctoral appointment at the Los Alamos National Laboratory in New Mexico. He returned to Cuba in 1980 as a member of an academic tour organized by the University of New Mexico in Albuquerque. This provided an introduction to various government-run scientific facilities in Havana and the easternmost city of "Santiago de Cuba" in the province of Oriente.

Continuous arteriovenous haemofiltration to regulate hyperkalaemia during renal transplantation: a case report.

PubMed

Tripathi, Mukesh; Kaushik, Soma; Pandey, Rajesh

2006-11-01

Progressive hyperkalaemia is common in end stage renal disease patients waiting for renal transplantation. Ventricular tachycardia and ventricular fibrillation due to hyperkalaemia are life-threatening complications in these patients. In live and related renal transplant, after induction and anaesthesia, ventricular fibrillation and pulmonary oedema occurred. After immediate resuscitation by defibrillation and intravenous injection of adrenaline, the patient was put on continuous femoral arteriovenous haemofiltration (CAVH). This improved his pulmonary oedema, controlled hyperkalaemia and surgery could be completed uninterruptedly. After anaesthetising live and related kidney donor for nephrectomy, since it is not prudent to stop recipient surgery because of unforeseen complication, the authors wish to recommend CAVH as an alternative method to prevent life threatening cardiac complication of hyperkalaemia.

Update on mechanical cardiopulmonary resuscitation devices.

PubMed

Rubertsson, Sten

2016-06-01

The aim of this review is to update and discuss the use of mechanical chest compression devices in treatment of cardiac arrest. Three recently published large multicenter randomized trials have not been able to show any improved outcome in adult out-of-hospital cardiac arrest patients when compared with manual chest compressions. Mechanical chest compression devices have been developed to better deliver uninterrupted chest compressions of good quality. Prospective large randomized studies have not been able to prove a better outcome compared to manual chest compressions; however, latest guidelines support their use when high-quality manual chest compressions cannot be delivered. Mechanical chest compressions can also be preferred during transportation, in the cath-lab and as a bridge to more invasive support like extracorporeal membrane oxygenation.

Re-Engineering the ISS Payload Operations Control Center During Increased Utilization and Critical Onboard Events

NASA Technical Reports Server (NTRS)

Marsh, Angela L.; Dudley, Stephanie R. B.

2014-01-01

With an increase in the utilization and hours of payload operations being executed onboard the International Space Station (ISS), upgrading the NASA Marshall Space Flight Center (MSFC) Huntsville Operations Support Center (HOSC) ISS Payload Control Area (PCA) was essential to gaining efficiencies and assurance of current and future payload health and science return. PCA houses the Payload Operations Integration Center (POIC) responsible for the execution of all NASA payloads onboard the ISS. POIC Flight Controllers are responsible for the operation of voice, stowage, command, telemetry, video, power, thermal, and environmental control in support of ISS science experiments. The methodologies and execution of the PCA refurbishment were planned and performed within a four month period in order to assure uninterrupted operation of ISS payloads and minimal impacts to payload operations teams. To vacate the PCA, three additional HOSC control rooms were reconfigured to handle ISS realtime operations, Backup Control Center (BCC) to Mission Control in Houston, simulations, and testing functions. This involved coordination and cooperation from teams of ISS operations controllers, multiple engineering and design disciplines, management, and construction companies performing an array of activities simultaneously and in sync delivering a final product with no issues that impacted the schedule. For each console operator discipline, studies of Information Technology (IT) tools and equipment layouts, ergonomics, and lines of sight were performed. Infusing some of the latest IT into the project was an essential goal in ensuring future growth and success of the ISS payload science returns. Engineering evaluations led to a state of the art media wall implementation and more efficient ethernet cabling distribution providing the latest products and the best solution for the POIC. These engineering innovations led to cost savings for the project. Constraints involved in the management of the project included executing over 450 crew-hours of ISS real-time payload operations including a major onboard communications upgrade, SpaceX un-berth, a Soyuz launch, roll-out of ISS live video and interviews from the POIC, annual BCC certification and hurricane season, and ISS simulations and testing. Continuous ISS payload operations were possible during the PCA facility modifications with the reconfiguration of four control rooms and standup of two temporary control areas. Another major restriction to the project was an ongoing facility upgrade that included a NASA Headquarters mandated replacement of all electrical and mechanical systems and replacement of an external generator. These upgrades required a facility power outage during the PCA upgrades. The project also encompassed console layout designs and ordering, amenities selections and ordering, excessing of old equipment, moves, disposal of old IT equipment, camera installations, facility tour re-schedules, and contract justifications. These were just some of the tasks needed for a successful project.

The role of coal technology in redefining India’s climate change agents and other pollutants

NASA Astrophysics Data System (ADS)

Sahu, S. K.; Ohara, T.; Beig, G.

2017-10-01

It is well established that carbon dioxide (CO2) is the most prominent agent of climate change. The level of CO2 in the atmosphere has been increasing persistently over the last few decades due to rising dependence on fossil fuels for energy production. India is facing a potential energy crisis. India has large coal reserves and coal is currently the linchpin of the Indian power sector, making Indian coal-derived emissions a focus of global attention. Further, India’s journey from a challenging energy security situation to the ‘Make in India’ initiative is expected to drive energy needs exponentially. Thus, in the context of a rapidly changing climate, it has become imperative to quantify the emissions of greenhouse gases (GHGs) from emerging coal-based energy plants in India. The present work attempts not only to do this, with the intention of highlighting India’s commitment to reducing CO2 emissions, but also to redefine India’s future emissions. We draw attention to India’s attempt to transform the coal technology used in coal-based thermal power plants. We have tried to adopt a holistic approach to quantify the past (2010), present (2015) and future (2025) emission trends for important GHGs like CO2 and other critical air pollutants from rapidly penetrating low-emission advanced coal technology. Our estimation shows that CO2 emissions will increase from 1065 Tg yr-1 (2015) to 2634 Tg yr-1 (2025), which is approximately 147% of the current value. This rapid increase is largely attributed to rising energy demand due to industrial development, followed by demand from the domestic and agricultural sectors. The present trend of CO2 emissions is sure to propel India to become world’s second largest emitter of GHGs in 2025, dislodging the United States. We have also estimated the emission of other pollutants like NOx, SO2, black carbon, organic carbon, particulate matter (PM2.5, PM10), volatile organic compounds and CO. Our findings seem to suggest that India will able to cut CO2 emission from the traditionally dominant thermal power sector by at least 19% in 2025. Present attempts at emission reduction, along with the government’s massive initiatives towards building renewable energy infrastructure, could be well aligned to India’s Intended Nationally Determined Contribution submission to COP21 of the United Nations Framework Convention on Climate Change. With such a rapid expansion of energy production it can be assumed that cost-effective and uninterrupted power (i.e. 24/7) can be provided to all citizens of the country well before 2025.

Design of an Input-Parallel Output-Parallel LLC Resonant DC-DC Converter System for DC Microgrids

NASA Astrophysics Data System (ADS)

Juan, Y. L.; Chen, T. R.; Chang, H. M.; Wei, S. E.

2017-11-01

Compared with the centralized power system, the distributed modularized power system is composed of several power modules with lower power capacity to provide a totally enough power capacity for the load demand. Therefore, the current stress of the power components in each module can then be reduced, and the flexibility of system setup is also enhanced. However, the parallel-connected power modules in the conventional system are usually controlled to equally share the power flow which would result in lower efficiency in low loading condition. In this study, a modular power conversion system for DC micro grid is developed with 48 V dc low voltage input and 380 V dc high voltage output. However, in the developed system control strategy, the numbers of power modules enabled to share the power flow is decided according to the output power at lower load demand. Finally, three 350 W power modules are constructed and parallel-connected to setup a modular power conversion system. From the experimental results, compared with the conventional system, the efficiency of the developed power system in the light loading condition is greatly improved. The modularized design of the power system can also decrease the power loss ratio to the system capacity.

Design and Implementation of Effective Electrical Power System for Surya Satellite-1

NASA Astrophysics Data System (ADS)

Sulistya, A. H.; Hasbi, W.; Muhida, R.

2018-05-01

Surya Satellite-1 is a nanosatellite developed by students of Surya University. The subject of this paper is the design and implementation of effective electrical power system for Surya Satellite 1. The electrical power system role is to supply other systems of the satellite with appropriate electrical power. First, the requirements of the electrical power system are defined. The architecture of the electrical power system is then designed to build the prototype. The orbit simulation is calculated to predict the power production. When prototype test and simulation data is gained, we make an operation scenario to keep the produced power and the consumed power in balance. The design of the modules of the electrical power system is carried out with triple junction solar cells, lithium ion batteries, maximum power point trackers, charging controllers, power distributions, and protection systems. Finally, the prototypes of the electrical power system are presented.

Power control and management of the grid containing largescale wind power systems

NASA Astrophysics Data System (ADS)

Aula, Fadhil Toufick

The ever increasing demand for electricity has driven many countries toward the installation of new generation facilities. However, concerns such as environmental pollution and global warming issues, clean energy sources, high costs associated with installation of new conventional power plants, and fossil fuels depletion have created many interests in finding alternatives to conventional fossil fuels for generating electricity. Wind energy is one of the most rapidly growing renewable power sources and wind power generations have been increasingly demanded as an alternative to the conventional fossil fuels. However, wind power fluctuates due to variation of wind speed. Therefore, large-scale integration of wind energy conversion systems is a threat to the stability and reliability of utility grids containing these systems. They disturb the balance between power generation and consumption, affect the quality of the electricity, and complicate load sharing and load distribution managing and planning. Overall, wind power systems do not help in providing any services such as operating and regulating reserves to the power grid. In order to resolve these issues, research has been conducted in utilizing weather forecasting data to improve the performance of the wind power system, reduce the influence of the fluctuations, and plan power management of the grid containing large-scale wind power systems which consist of doubly-fed induction generator based energy conversion system. The aims of this research, my dissertation, are to provide new methods for: smoothing the output power of the wind power systems and reducing the influence of their fluctuations, power managing and planning of a grid containing these systems and other conventional power plants, and providing a new structure of implementing of latest microprocessor technology for controlling and managing the operation of the wind power system. In this research, in order to reduce and smooth the fluctuations, two methods are presented. The first method is based on a de-loaded technique while the other method is based on utilizing multiple storage facilities. The de-loaded technique is based on characteristics of the power of a wind turbine and estimation of the generated power according to weather forecasting data. The technique provides a reference power by which the wind power system will operate and generate a smooth power. In contrast, utilizing storage facilities will allow the wind power system to operate at its maximum tracking power points' strategy. Two types of energy storages are considered in this research, battery energy storage system (BESS) and pumped-hydropower storage system (PHSS), to suppress the output fluctuations and to support the wind power system to follow the system load demands. Furthermore, this method provides the ability to store energy when there is a surplus of the generated power and to reuse it when there is a shortage of power generation from wind power systems. Both methods are new in terms of utilizing of the techniques and wind speed data. A microprocessor embedded system using an IntelRTM Atom(TM) processor is presented for controlling the wind power system and for providing the remote communication for enhancing the operation of the individual wind power system in a wind farm. The embedded system helps the wind power system to respond and to follow the commands of the central control of the power system. Moreover, it enhances the performance of the wind power system through self-managing, self-functioning, and self-correcting. Finally, a method of system power management and planning is modeled and studied for a grid containing large-scale wind power systems. The method is based on a new technique through constructing a new load demand curve (NLDC) from merging the estimation of generated power from wind power systems and forecasting of the load. To summarize, the methods and their results presented in this dissertation, enhance the operation of the large-scale wind power systems and reduce their drawbacks on the operation of the power grid.

Power System Information Delivering System Based on Distributed Object

NASA Astrophysics Data System (ADS)

Tanaka, Tatsuji; Tsuchiya, Takehiko; Tamura, Setsuo; Seki, Tomomichi; Kubota, Kenji

In recent years, improvement in computer performance and development of computer network technology or the distributed information processing technology has a remarkable thing. Moreover, the deregulation is starting and will be spreading in the electric power industry in Japan. Consequently, power suppliers are required to supply low cost power with high quality services to customers. Corresponding to these movements the authors have been proposed SCOPE (System Configuration Of PowEr control system) architecture for distributed EMS/SCADA (Energy Management Systems / Supervisory Control and Data Acquisition) system based on distributed object technology, which offers the flexibility and expandability adapting those movements. In this paper, the authors introduce a prototype of the power system information delivering system, which was developed based on SCOPE architecture. This paper describes the architecture and the evaluation results of this prototype system. The power system information delivering system supplies useful power systems information such as electric power failures to the customers using Internet and distributed object technology. This system is new type of SCADA system which monitors failure of power transmission system and power distribution system with geographic information integrated way.

Geophysical Hazards and Preventive Disaster Management of Extreme Natural Events

NASA Astrophysics Data System (ADS)

Ismail-Zadeh, A.; Takeuchi, K.

2007-12-01

Geophysical hazard is potentially damaging natural event and/or phenomenon, which may cause the loss of life or injury, property damage, social and economic disruption, or environmental degradation. Extreme natural hazards are a key manifestation of the complex hierarchical nonlinear Earth system. An understanding, accurate modeling and forecasting of the extreme hazards are most important scientific challenges. Several recent extreme natural events (e.g., 2004 Great Indian Ocean Earthquake and Tsunami and the 2005 violent Katrina hurricane) demonstrated strong coupling between solid Earth and ocean, and ocean and atmosphere. These events resulted in great humanitarian tragedies because of a weak preventive disaster management. The less often natural events occur (and the extreme events are rare by definition), the more often the disaster managers postpone the preparedness to the events. The tendency to reduce the funding for preventive disaster management of natural catastrophes is seldom follows the rules of responsible stewardship for future generations neither in developing countries nor in highly developed economies where it must be considered next to malfeasance. Protecting human life and property against earthquake disasters requires an uninterrupted chain of tasks: from (i) understanding of physics of the events, analysis and monitoring, through (ii) interpretation, modeling, hazard assessment, and prediction, to (iii) public awareness, preparedness, and preventive disaster management.

Vernalizing cold is registered digitally at FLC.

PubMed

Angel, Andrew; Song, Jie; Yang, Hongchun; Questa, Julia I; Dean, Caroline; Howard, Martin

2015-03-31

A fundamental property of many organisms is an ability to sense, evaluate, and respond to environmental signals. In some situations, generation of an appropriate response requires long-term information storage. A classic example is vernalization, where plants quantitatively sense long-term cold and epigenetically store this cold-exposure information to regulate flowering time. In Arabidopsis thaliana, stable epigenetic memory of cold is digital: following long-term cold exposure, cells respond autonomously in an all-or-nothing fashion, with the fraction of cells that stably silence the floral repressor flowering locus C (FLC) increasing with the cold exposure duration. However, during cold exposure itself it is unknown whether vernalizing cold is registered at FLC in individual cells in an all-or-nothing (digital) manner or is continuously varying (analog). Using mathematical modeling, we found that analog registration of cold temperature is problematic due to impaired analog-to-digital conversion into stable memory. This disadvantage is particularly acute when responding to short cold periods, but is absent when cold temperatures are registered digitally at FLC. We tested this prediction experimentally, exposing plants to short periods of cold interrupted with even shorter warm breaks. For FLC expression, we found that the system responds similarly to both interrupted and uninterrupted cold, arguing for a digital mechanism integrating long-term temperature exposure.

Evaluation of data thinning strategies for climate applications using the first four years of AIRS hyperspectral data

NASA Astrophysics Data System (ADS)

Aumann, Hartmut H.; Fishbein, Evan; Gohlke, Jan

2007-09-01

The application of infrared hyper-spectral sounder data to climate research requires the global analysis of multi-decadal time series of various atmosphere, surface or cloud related parameters. The data used in this analysis has to meet stringent global and scene independent absolute accuracy and stability requirements, it also has to be spatially and radiometrically unbiased, manageable in size and self-contained. Self-contained means that the data set contains not only a globally unbiased sample of the state of the Earth Climate system as seen in the infrared, it has to contain enough data to contrast clear with average (cloudy) data and to allow an independent assessment of the radiometric and spectral accuracy and stability of the data. We illustrate this with data from the Atmospheric Infrared Sounder (AIRS) and Infrared Atmospheric Sounder Interferometer (IASI) data. AIRS and IASI were designed with fairly similar functional requirements. AIRS was launched on the EOS Aqua spacecraft in May 2002 into a 705 km polar sun-synchronous orbit with accurately maintained 1:30 PM ascending node. Essentially un-interrupted data are available since September 2002. Since October 2006 IASI is in a 9:30 AM polar orbit at 815 km altitude on the MetOp2 satellite, with data available since May 2007.

Vernalizing cold is registered digitally at FLC

PubMed Central

Angel, Andrew; Song, Jie; Yang, Hongchun; Questa, Julia I.; Dean, Caroline; Howard, Martin

2015-01-01

A fundamental property of many organisms is an ability to sense, evaluate, and respond to environmental signals. In some situations, generation of an appropriate response requires long-term information storage. A classic example is vernalization, where plants quantitatively sense long-term cold and epigenetically store this cold-exposure information to regulate flowering time. In Arabidopsis thaliana, stable epigenetic memory of cold is digital: following long-term cold exposure, cells respond autonomously in an all-or-nothing fashion, with the fraction of cells that stably silence the floral repressor FLOWERING LOCUS C (FLC) increasing with the cold exposure duration. However, during cold exposure itself it is unknown whether vernalizing cold is registered at FLC in individual cells in an all-or-nothing (digital) manner or is continuously varying (analog). Using mathematical modeling, we found that analog registration of cold temperature is problematic due to impaired analog-to-digital conversion into stable memory. This disadvantage is particularly acute when responding to short cold periods, but is absent when cold temperatures are registered digitally at FLC. We tested this prediction experimentally, exposing plants to short periods of cold interrupted with even shorter warm breaks. For FLC expression, we found that the system responds similarly to both interrupted and uninterrupted cold, arguing for a digital mechanism integrating long-term temperature exposure. PMID:25775579

Satellite Reveals How Much Saharan Dust Feeds Amazon's Plants

NASA Image and Video Library

2015-02-24

What connects Earth's largest, hottest desert to its largest tropical rainforest? The Sahara Desert is a near-uninterrupted brown band of sand and scrub across the northern third of Africa. The Amazon rainforest is a dense green mass of humid jungle that covers northeast South America. But after strong winds sweep across the Sahara, a tan cloud rises in the air, stretches between the continents, and ties together the desert and the jungle. It’s dust. And lots of it. For the first time, a NASA satellite has quantified in three dimensions how much dust makes this trans-Atlantic journey. Scientists have not only measured the volume of dust, they have also calculated how much phosphorus – a natural plant fertilizer present in Saharan sands from part of the desert’s past as a lake bed – gets carried across the ocean from one of the planet’s most desolate places to one of its most fertile. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Analytical study of nighttime scintillations using GPS at low latitude station Bhopal

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maski, Kalpana, E-mail: k-maski@rediffmail.com; Vijay, S. K.

2015-07-31

Sporadically structured ionosphere (i.e. in-homogeneities in refractive index) can cause fluctuations (due to refraction effects) on the radio signal that is passing through it. These fluctuations are called ionospheric scintillations. Low latitude region is suitable for studying these scintillations. The influence of the ionosphere on the propagation of the radio wave becomes very marked with reference to communication or navigational radio system at very low frequency (VLF) to a high frequency (HF), which operate over the distances of 1000 km or more. Radio wave communication at different frequencies depends on structure of the ionosphere. With the advent of the artificialmore » satellites, they are used as a prime mode of radio wave communication. Some natural perturbation termed as irregularities, are present in the form of electron density of the ionosphere that cause disruption in the radio and satellite communications. Therefore the study of the ionospheric irregularities is of practical importance, if one wishes to understand the upper atmosphere completely. In order to make these communications uninterrupted the knowledge of irregularities, which are present in the ionosphere are very important. These irregularities can be located and estimated with the help of Ionospheric TEC and Scintillation. Scintillation is generally confined to nighttime hours, particularly around equatorial and low latitudes.« less

Quick detection of QRS complexes and R-waves using a wavelet transform and K-means clustering.

PubMed

Xia, Yong; Han, Junze; Wang, Kuanquan

2015-01-01

Based on the idea of telemedicine, 24-hour uninterrupted monitoring on electrocardiograms (ECG) has started to be implemented. To create an intelligent ECG monitoring system, an efficient and quick detection algorithm for the characteristic waveforms is needed. This paper aims to give a quick and effective method for detecting QRS-complexes and R-waves in ECGs. The real ECG signal from the MIT-BIH Arrhythmia Database is used for the performance evaluation. The method proposed combined a wavelet transform and the K-means clustering algorithm. A wavelet transform is adopted in the data analysis and preprocessing. Then, based on the slope information of the filtered data, a segmented K-means clustering method is adopted to detect the QRS region. Detection of the R-peak is based on comparing the local amplitudes in each QRS region, which is different from other approaches, and the time cost of R-wave detection is reduced. Of the tested 8 records (total 18201 beats) from the MIT-BIH Arrhythmia Database, an average R-peak detection sensitivity of 99.72 and a positive predictive value of 99.80% are gained; the average time consumed detecting a 30-min original signal is 5.78s, which is competitive with other methods.

Acute gastrointestinal illness following a prolonged community-wide water emergency.

PubMed

Gargano, J W; Freeland, A L; Morrison, M A; Stevens, K; Zajac, L; Wolkon, A; Hightower, A; Miller, M D; Brunkard, J M

2015-10-01

The drinking water infrastructure in the United States is ageing; extreme weather events place additional stress on water systems that can lead to interruptions in the delivery of safe drinking water. We investigated the association between household exposures to water service problems and acute gastrointestinal illness (AGI) and acute respiratory illness (ARI) in Alabama communities that experienced a freeze-related community-wide water emergency. Following the water emergency, investigators conducted a household survey. Logistic regression models were used to estimate adjusted prevalence ratios (aPR) and 95% confidence intervals (CI) for self-reported AGI and ARI by water exposures. AGI was higher in households that lost water service for ⩾7 days (aPR 2·4, 95% CI 1·1-5·2) and experienced low water pressure for ⩾7 days (aPR 3·6, 95% CI 1·4-9·0) compared to households that experienced normal service and pressure; prevalence of AGI increased with increasing duration of water service interruptions. Investments in the ageing drinking water infrastructure are needed to prevent future low-pressure events and to maintain uninterrupted access to the fundamental public health protection provided by safe water supplies. Households and communities need to increase their awareness of and preparedness for water emergencies to mitigate adverse health impacts.

Estimating the impacts of wind power on power systems—summary of IEA Wind collaboration

NASA Astrophysics Data System (ADS)

Holttinen, Hannele

2008-04-01

Adding wind power to power systems will have beneficial impacts by reducing the emissions of electricity production and reducing the operational costs of the power system as less fuel is consumed in conventional power plants. Wind power will also have a capacity value to a power system. However, possible negative impacts will have to be assessed to make sure that they will only offset a small part of the benefits and also to ensure the security of the power system operation. An international forum for the exchange of knowledge of power system impacts of wind power has been formed under the IEA Implementing Agreement on Wind Energy. The Task 'Design and Operation of Power Systems with Large Amounts of Wind Power' is analyzing existing case studies from different power systems. There are a multitude of studies completed and ongoing related to the cost of wind integration. However, the results are not easy to compare. This paper describes the general issues of wind power impacts on power systems and presents a comparison of results from ten case studies on increased balancing needs due to wind power.