Malfunction and failure of robotic systems during general surgical procedures.

PubMed

Agcaoglu, Orhan; Aliyev, Shamil; Taskin, Halit Eren; Chalikonda, Sricharan; Walsh, Matthew; Costedio, Meagan M; Kroh, Matthew; Rogula, Tomasz; Chand, Bipan; Gorgun, Emre; Siperstein, Allan; Berber, Eren

2012-12-01

There has been recent interest in using robots for general surgical procedures. This shift in technique raises the issue of patient safety with automated instrumentation. Although the safety of robotics has been established for urologic procedures, there are scant data on its use in general surgical procedures. The aim of this study is to analyze the incidence of robotic malfunction and its consequences for general surgical procedures. All robotic general surgical procedures performed at a tertiary center between 2008 and 2011 were reviewed from institutional review board (IRB)-approved prospective databases. A total of 223 cases were done robotically, including 102 endocrine, 83 hepatopancreaticobiliary, 17 upper gastrointestinal, and 21 lower gastrointestinal colorectal procedures. There were 10 cases of robotic malfunction (4.5%). These failures were related to robotic instruments (n = 4), optical system (n = 3), robotic arms (n = 2), and robotic console (n = 1). None of these failures led to adverse patient consequences or conversion to open. Six (2.7%) cases were converted to open due to bleeding (n = 3), difficult dissection plane (n = 1), invasion of tumor to surrounding structures (n = 1), and intolerance of pneumoperitoneum due to CO(2) retention (n = 1). There was no mortality, and morbidity was 1% (n = 2). To our knowledge, this is the largest North American report to date on robotic general surgical procedures. Our results show that robotic malfunction occurs in a minority of cases, with no adverse consequences. We believe that awareness of these failures and knowing how to troubleshoot are important to maintain the efficiency of these procedures.

Adverse Events in Robotic Surgery: A Retrospective Study of 14 Years of FDA Data

PubMed Central

Alemzadeh, Homa; Raman, Jaishankar; Leveson, Nancy; Kalbarczyk, Zbigniew; Iyer, Ravishankar K.

2016-01-01

Background Use of robotic systems for minimally invasive surgery has rapidly increased during the last decade. Understanding the causes of adverse events and their impact on patients in robot-assisted surgery will help improve systems and operational practices to avoid incidents in the future. Methods By developing an automated natural language processing tool, we performed a comprehensive analysis of the adverse events reported to the publicly available MAUDE database (maintained by the U.S. Food and Drug Administration) from 2000 to 2013. We determined the number of events reported per procedure and per surgical specialty, the most common types of device malfunctions and their impact on patients, and the potential causes for catastrophic events such as patient injuries and deaths. Results During the study period, 144 deaths (1.4% of the 10,624 reports), 1,391 patient injuries (13.1%), and 8,061 device malfunctions (75.9%) were reported. The numbers of injury and death events per procedure have stayed relatively constant (mean = 83.4, 95% confidence interval (CI), 74.2–92.7 per 100,000 procedures) over the years. Surgical specialties for which robots are extensively used, such as gynecology and urology, had lower numbers of injuries, deaths, and conversions per procedure than more complex surgeries, such as cardiothoracic and head and neck (106.3 vs. 232.9 per 100,000 procedures, Risk Ratio = 2.2, 95% CI, 1.9–2.6). Device and instrument malfunctions, such as falling of burnt/broken pieces of instruments into the patient (14.7%), electrical arcing of instruments (10.5%), unintended operation of instruments (8.6%), system errors (5%), and video/imaging problems (2.6%), constituted a major part of the reports. Device malfunctions impacted patients in terms of injuries or procedure interruptions. In 1,104 (10.4%) of all the events, the procedure was interrupted to restart the system (3.1%), to convert the procedure to non-robotic techniques (7.3%), or to reschedule it (2.5%). Conclusions Despite widespread adoption of robotic systems for minimally invasive surgery in the U.S., a non-negligible number of technical difficulties and complications are still being experienced during procedures. Adoption of advanced techniques in design and operation of robotic surgical systems and enhanced mechanisms for adverse event reporting may reduce these preventable incidents in the future. PMID:27097160

TECHNICAL SUPPORT TO NASA

EPA Science Inventory

The Pluto-New Horizon Mission will use a radioisotope thermoelectric generator fueled by plutonium-238 to provide electric power for the scientific instruments. This activity plans for actions to be taken if there is a malfunction during the launch. Also, EPA's RPD provided tec...

Online Vibration Monitoring of a Water Pump Machine to Detect Its Malfunction Components Based on Artificial Neural Network

NASA Astrophysics Data System (ADS)

Rahmawati, P.; Prajitno, P.

2018-04-01

Vibration monitoring is a measurement instrument used to identify, predict, and prevent failures in machine instruments[6]. This is very needed in the industrial applications, cause any problem with the equipment or plant translates into economical loss and they are mostly monitored component off-line[2]. In this research, a system has been developed to detect the malfunction of the components of Shimizu PS-128BT water pump machine, such as capacitor, bearing and impeller by online measurements. The malfunction components are detected by taking vibration data using a Micro-Electro-Mechanical System(MEMS)-based accelerometer that are acquired by using Raspberry Pi microcomputer and then the data are converted into the form of Relative Power Ratio(RPR). In this form the signal acquired from different components conditions have different patterns. The collected RPR used as the base of classification process for recognizing the damage components of the water pump that are conducted by Artificial Neural Network(ANN). Finally, the damage test result will be sent via text message using GSM module that are connected to Raspberry Pi microcomputer. The results, with several measurement readings, with each reading in 10 minutes duration for each different component conditions, all cases yield 100% of accuracies while in the case of defective capacitor yields 90% of accuracy.

A MATLAB/Simulink based GUI for the CERES Simulator

NASA Technical Reports Server (NTRS)

Valencia, Luis H.

1995-01-01

The Clouds and The Earth's Radiant Energy System (CERES) simulator will allow flight operational familiarity with the CERES instrument prior to launch. It will provide a CERES instrument simulation facility for NASA Langley Research Center. NASA Goddard Space Flight Center and TRW. One of the objectives of building this simulator would be for use as a testbed for functionality checking of atypical memory uploads and for anomaly investigation. For instance, instrument malfunction due to memory damage requires troubleshooting on a simulator to determine the nature of the problem and to find a solution.

Global robotic experience and the type of surgical system impact the types of robotic malfunctions and their clinical consequences: an FDA MAUDE review.

PubMed

Lucas, Steven M; Pattison, Erik A; Sundaram, Chandru P

2012-04-01

To assess annual rates of robotic system malfunctions and compare the da Vinci S(®) system (dVS) and da Vinci(®) surgical system (dV). To assess the types of malfunctions and associated outcomes for robotic cases and determine the extent to which experience and technological improvements impact these. This study is a retrospective review of the US Food and Drug Administration (FDA) MAUDE (Manufacturer and User Facility Device Experience) database, a publicly available, voluntary reporting system (http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfmaude/search.cfm). The database was searched using the two phrases 'da Vinci' and 'Intuitive Surgical' from 2003 to 2009. Malfunctions of the instruments, console, patient-side cart, camera and cannula were recorded. Data on intraoperative injuries, case delays and conversions were also collected. In all, 1914 reports were reviewed (991 dVS and 878 dV, 45 unclassified) with peak years for reports of 2008 for dVS (571) and 2007 for dV (211), P < 0.001. With respect to time, the proportion of console and patient-side cart malfunctions declined from 2007 onward compared with the proportions prior to 2007 (5.1% vs 9.4% and 6.6% vs 10.9%). Patient injury did not change with year of surgery (0.5-5.4% of malfunctions, P= 0.358), open conversions declined (21.3% of malfunctions before 2007 vs 9.9% from 2007 onward, P < 0.001) and patient deaths increased (0.0013% of cases before 2007 vs 0.0061% of cases from 2007 onward, P < 0.001). With regard to robotic system, console and patient-side cart malfunctions were more frequent with the dV than the dVS: 82/878 vs 39/991 and 100/878 vs 48/991, P < 0.001. Open conversion was more frequent with dV than dVS (19.3% vs 7.7% of reported malfunctions, P < 0.001), while patient injury was less with dV than dVS (3.5% vs 5.9%, P= 0.021). The dVS decreased console and patient-side cart errors relative to total malfunctions, which were also influenced by surgical year. Open conversions were reduced by increased robotic experience and newer surgical system. Differences in patient injury may reflect changes in reporting or case complexity. © 2011 THE AUTHORS. BJU INTERNATIONAL © 2011 BJU INTERNATIONAL.

75 FR 4111 - Biweekly Notice; Applications and Amendments to Facility Operating Licenses Involving No...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-26

... addition, the requestor/petitioner shall provide a brief explanation of the bases for the contention and a..., malfunctions, or accident initiators not considered in the design and licensing bases. The proposed amendment... technical specifications (TSs) requirements related to primary containment isolation instrumentation in...

Apollo 12, 15, and 16 lunar surface magnetometer experiment data analysis

NASA Technical Reports Server (NTRS)

Sonett, C. P.

1975-01-01

The polarization of magnetometer signals detected at the Apollo 15 Hadley site by the lunar surface magnetometer has been studied to determine the source of the signal anisotropy which is observed and caused by the polarization. Instrument and data chain malfunction (cross-talk) seems ruled out. The source appears real and apparently connected with the Imbrium basin using reasonable inferences regarding the electromagnetic structure of the Moon. A theory is developed using moons with holes and conducting caps where the Imbrium basin is; results of calculations are consistent, though not unique, in specifying an anomaly in the electrical conductivity underlying Mare Imbrium. Distinct differences are noted from plasma sheet and diamagnetic cavity transfer functions, but the lobes appear, as for all other data, not to be vacuum for study of the moon. A discussion is given of problems connected with transfer of data, software, and theoretical programs from NASA Ames Research Center to the University of Arizona, and a summary is given of the conversion from IBM to CDC formats.

Challenges of Maintaining Good Clinical Laboratory Practices in Low-Resource Settings:  A Health Program Evaluation Framework Case Study From East Africa.

PubMed

Zhang, Helen L; Omondi, Michael W; Musyoka, Augustine M; Afwamba, Isaac A; Swai, Remigi P; Karia, Francis P; Muiruri, Charles; Reddy, Elizabeth A; Crump, John A; Rubach, Matthew P

2016-08-01

Using a clinical research laboratory as a case study, we sought to characterize barriers to maintaining Good Clinical Laboratory Practice (GCLP) services in a developing world setting. Using a US Centers for Disease Control and Prevention framework for program evaluation in public health, we performed an evaluation of the Kilimanjaro Christian Medical Centre-Duke University Health Collaboration clinical research laboratory sections of the Kilimanjaro Clinical Research Institute in Moshi, Tanzania. Laboratory records from November 2012 through October 2014 were reviewed for this analysis. During the 2-year period of study, seven instrument malfunctions suspended testing required for open clinical trials. A median (range) of 9 (1-55) days elapsed between instrument malfunction and biomedical engineer service. Sixteen (76.1%) of 21 suppliers of reagents, controls, and consumables were based outside Tanzania. Test throughput among laboratory sections used a median (range) of 0.6% (0.2%-2.7%) of instrument capacity. Five (55.6%) of nine laboratory technologists left their posts over 2 years. These findings demonstrate that GCLP laboratory service provision in this setting is hampered by delays in biomedical engineer support, delays and extra costs in commodity procurement, low testing throughput, and high personnel turnover. © American Society for Clinical Pathology, 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

An Overview of the NASA Aviation Safety Program Propulsion Health Monitoring Element

NASA Technical Reports Server (NTRS)

Simon, Donald L.

2000-01-01

The NASA Aviation Safety Program (AvSP) has been initiated with aggressive goals to reduce the civil aviation accident rate, To meet these goals, several technology investment areas have been identified including a sub-element in propulsion health monitoring (PHM). Specific AvSP PHM objectives are to develop and validate propulsion system health monitoring technologies designed to prevent engine malfunctions from occurring in flight, and to mitigate detrimental effects in the event an in-flight malfunction does occur. A review of available propulsion system safety information was conducted to help prioritize PHM areas to focus on under the AvSP. It is noted that when a propulsion malfunction is involved in an aviation accident or incident, it is often a contributing factor rather than the sole cause for the event. Challenging aspects of the development and implementation of PHM technology such as cost, weight, robustness, and reliability are discussed. Specific technology plans are overviewed including vibration diagnostics, model-based controls and diagnostics, advanced instrumentation, and general aviation propulsion system health monitoring technology. Propulsion system health monitoring, in addition to engine design, inspection, maintenance, and pilot training and awareness, is intrinsic to enhancing aviation propulsion system safety.

[Malfunction simulation by spaceflight training simulator].

PubMed

Chang, Tian-chun; Zhang, Lian-hua; Xue, Liang; Lian, Shun-guo

2005-04-01

To implement malfunction simulation in spaceflight training simulator. The principle of malfunction simulation was defined according to spacecraft malfunction predict and its countermeasures. The malfunction patterns were classified, and malfunction type was confirmed. A malfunction simulation model was established, and the malfunction simulation was realized by math simulation. According to the requirement of astronaut training, a spacecraft subsystem malfunction simulation model was established and realized, such as environment control and life support, GNC, push, power supply, heat control, data management, measure control and communication, structure and so on. The malfunction simulation function implemented in the spaceflight training simulator satisfied the requirements for astronaut training.

Enabling Medical Device Interoperability for the Integrated Clinical Environment

DTIC Science & Technology

2013-08-01

include the unique device identifier (UDI) as specified by the FDA , a logical timestamp as described above, and the data. 17 Existing adverse event...failure or malfunction that led to an adverse effect during a medical procedure. User: clinical and legal experts, IT-experts, biomed experts...diagnosis, treatment, research, safety and quality improvements, equipment management, and adverse event detection and reporting . The Medical

Utilization of an Airborne Plant Chlorophyll Imaging System for Detection of Septic System Malfunction

NASA Technical Reports Server (NTRS)

Spiering, Bruce A.; Carter, Gregory A.

2001-01-01

Malfunctioning, or leaking, sewer systems increase the supply of water and nutrients to surface vegetation. Excess nutrients and harmful bacteria in the effluent pollute ground water and local water bodies and are dangerous to humans and the aquatic ecosystems. An airborne multispectral plant chlorophyll imaging system (PCIS) was used to identify growth patterns in the vegetation covering onsite and public sewer systems. The objective was to evaluate overall performance of the PCIS as well as to determine the best operational configuration for this application. The imaging system was flown in a light aircraft over selected locations Mobile County, Alabama. Calibration panels were used to help characterize instrument performance. Results demonstrated that the PCIS performed well and was capable of detecting septic leakage patterns from altitudes as high as 915 m. From 915 m, 6 of 18 sites were suspected to have sewage leakage. Subsequent ground inspections confirmed leakage on 3 of the 6 sites. From 610 m, 3 of 8 known leakage sites were detected. Tree cover and shadows near residential structures prevented detection of several known malfunctioning systems. Also some leakages known to occur in clear areas were not detected. False detections occurred in areas characterized by surface water drainage problems or recent excavation.

Assessment of Pneumatic Controller Emission Measurements ...

EPA Pesticide Factsheets

Oil and Natural Gas (ONG) production facilities have the potential to emit greenhouse gases such as methane (CH4) and other hydrocarbons (HCs) to the atmosphere. ONG production sites have multiple emission sources including storage tank venting, enclosed combustion devices, engine exhaust, pneumatic controllers and uncontrolled leaks. Accounting for up to 37.8 percent of CH4 emissions, pneumatic controllers are one of the most significant sources of CH4 in ONG production field operations. Recent measurement studies used the only commercially-available high volume sampling (HVS) technology (Bacharach Hi Flow Sampler, Bacharach, Inc., New Kensington, PA) to quantify CH4 emission rates of pneumatic devices on ONG production pads and compare to inventory estimates. Other studies indicate that this HVS may malfunction, causing underestimates of emissions in certain scenarios encountered in ONG production and should not be used for some sources such as heavy emissions from condensate storage tanks. The HVS malfunction can occur on relatively large emissions, where the measured leak concentrations exceed 5%, and is ascribed to a sensor transition failure in the instrument. The HVS malfunction is believed to be exacerbated by several factors (large emission rates, amount of non-CH4 HCs in the emission stream, non-optimal HVS calibration frequency, firmware, and emission measurement coupling geometries). The degree to which HVS measurements of emissions from pneumatic co

Analysis of clinical decision support system malfunctions: a case series and survey

PubMed Central

Wright, Adam; Hickman, Thu-Trang T; McEvoy, Dustin; Aaron, Skye; Ai, Angela; Andersen, Jan Marie; Hussain, Salman; Ramoni, Rachel; Fiskio, Julie; Sittig, Dean F; Bates, David W

2016-01-01

Objective To illustrate ways in which clinical decision support systems (CDSSs) malfunction and identify patterns of such malfunctions. Materials and Methods We identified and investigated several CDSS malfunctions at Brigham and Women’s Hospital and present them as a case series. We also conducted a preliminary survey of Chief Medical Information Officers to assess the frequency of such malfunctions. Results We identified four CDSS malfunctions at Brigham and Women’s Hospital: (1) an alert for monitoring thyroid function in patients receiving amiodarone stopped working when an internal identifier for amiodarone was changed in another system; (2) an alert for lead screening for children stopped working when the rule was inadvertently edited; (3) a software upgrade of the electronic health record software caused numerous spurious alerts to fire; and (4) a malfunction in an external drug classification system caused an alert to inappropriately suggest antiplatelet drugs, such as aspirin, for patients already taking one. We found that 93% of the Chief Medical Information Officers who responded to our survey had experienced at least one CDSS malfunction, and two-thirds experienced malfunctions at least annually. Discussion CDSS malfunctions are widespread and often persist for long periods. The failure of alerts to fire is particularly difficult to detect. A range of causes, including changes in codes and fields, software upgrades, inadvertent disabling or editing of rules, and malfunctions of external systems commonly contribute to CDSS malfunctions, and current approaches for preventing and detecting such malfunctions are inadequate. Conclusion CDSS malfunctions occur commonly and often go undetected. Better methods are needed to prevent and detect these malfunctions. PMID:27026616

Analysis of clinical decision support system malfunctions: a case series and survey.

PubMed

Wright, Adam; Hickman, Thu-Trang T; McEvoy, Dustin; Aaron, Skye; Ai, Angela; Andersen, Jan Marie; Hussain, Salman; Ramoni, Rachel; Fiskio, Julie; Sittig, Dean F; Bates, David W

2016-11-01

To illustrate ways in which clinical decision support systems (CDSSs) malfunction and identify patterns of such malfunctions. We identified and investigated several CDSS malfunctions at Brigham and Women's Hospital and present them as a case series. We also conducted a preliminary survey of Chief Medical Information Officers to assess the frequency of such malfunctions. We identified four CDSS malfunctions at Brigham and Women's Hospital: (1) an alert for monitoring thyroid function in patients receiving amiodarone stopped working when an internal identifier for amiodarone was changed in another system; (2) an alert for lead screening for children stopped working when the rule was inadvertently edited; (3) a software upgrade of the electronic health record software caused numerous spurious alerts to fire; and (4) a malfunction in an external drug classification system caused an alert to inappropriately suggest antiplatelet drugs, such as aspirin, for patients already taking one. We found that 93% of the Chief Medical Information Officers who responded to our survey had experienced at least one CDSS malfunction, and two-thirds experienced malfunctions at least annually. CDSS malfunctions are widespread and often persist for long periods. The failure of alerts to fire is particularly difficult to detect. A range of causes, including changes in codes and fields, software upgrades, inadvertent disabling or editing of rules, and malfunctions of external systems commonly contribute to CDSS malfunctions, and current approaches for preventing and detecting such malfunctions are inadequate. CDSS malfunctions occur commonly and often go undetected. Better methods are needed to prevent and detect these malfunctions. © The Author 2016. Published by Oxford University Press on behalf of the American Medical Informatics Association.

Minilaparotomy salvage of malfunctioning catheters in peritoneal dialysis.

PubMed

Li, Jian-Ri; Cheng, Chi-Hung; Chiu, Kun-Yuan; Cheng, Chen-Li; Yang, Chi-Rei; Ho, Hao-Chung; Ko, Jiunn-Liang; Ou, Yen-Chuan

2013-01-01

Catheter malfunction is a common and significant complication during peritoneal dialysis (PD). We developed a minilaparotomy procedure to rescue malfunctioning catheters and to prevent recurrence of malfunction. From 2006 to 2011, 11 patients receiving PD had a malfunctioning catheter. In all patients, a 2-cm incision, 5 cm caudally to the previous peritoneal entry site was used to correct the malfunctioning catheter, with concomitant fixation of the catheter to the peritoneum. Catheter tip migration occurred in 7 patients, omental wrapping in 3, and blood clot obstruction in 1. The mean onset time to catheter malfunction was 197.5 days (range: 4 - 1270 days), and the mean operating time was 41 minutes (range: 35 - 56 minutes). There was no recurrence of catheter malfunction and no surgery-related peritonitis. Our minilaparotomy procedure is safe and feasible for the salvage of malfunctioning PD catheters.

14 CFR 417.209 - Malfunction turn analysis.

Code of Federal Regulations, 2013 CFR

2013-01-01

... turn behavior for each cause of a malfunction turn. For each malfunction turn envelope, the analysis... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Malfunction turn analysis. 417.209 Section..., DEPARTMENT OF TRANSPORTATION LICENSING LAUNCH SAFETY Flight Safety Analysis § 417.209 Malfunction turn...

14 CFR 417.209 - Malfunction turn analysis.

Code of Federal Regulations, 2012 CFR

2012-01-01

... turn behavior for each cause of a malfunction turn. For each malfunction turn envelope, the analysis... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Malfunction turn analysis. 417.209 Section..., DEPARTMENT OF TRANSPORTATION LICENSING LAUNCH SAFETY Flight Safety Analysis § 417.209 Malfunction turn...

14 CFR 417.209 - Malfunction turn analysis.

Code of Federal Regulations, 2014 CFR

2014-01-01

... turn behavior for each cause of a malfunction turn. For each malfunction turn envelope, the analysis... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Malfunction turn analysis. 417.209 Section..., DEPARTMENT OF TRANSPORTATION LICENSING LAUNCH SAFETY Flight Safety Analysis § 417.209 Malfunction turn...

Effects of Automation on Aircrew Workload and Situation Awareness in Tactical Airlift Missions

DTIC Science & Technology

2015-12-24

autopilot (Hall, 1996; FAA). The inability of the crew to manually override the autopilot and mode confusion was causal to the Exxon Valdez oil spill...malfunctioned. In the case of a loss in propeller hydraulic fluid (“Prop Low Oil ” light), a warning light illuminates on the engine instrument stack...2013). Analysis of workload of tank crew under the conditions of informatization . Beijing: China North Vehicle Research Institute. Martin, G

What ASRS incident data tell about flight crew performance during aircraft malfunctions

NASA Technical Reports Server (NTRS)

Sumwalt, Robert L.; Watson, Alan W.

1995-01-01

This research examined 230 reports in NASA's Aviation Safety Reporting System's (ASRS) database to develop a better understanding of factors that can affect flight crew performance when crew are faced with inflight aircraft malfunctions. Each report was placed into one of two categories, based on severity of the malfunction. Report analysis was then conducted to extract information regarding crew procedural issues, crew communications and situational awareness. A comparison of these crew factors across malfunction type was then performed. This comparison revealed a significant difference in ways that crews dealt with serious malfunctions compared to less serious malfunctions. The authors offer recommendations toward improving crew performance when faced with inflight aircraft malfunctions.

On line instrument systems for monitoring steam turbogenerators

NASA Astrophysics Data System (ADS)

Clapis, A.; Giorgetti, G.; Lapini, G. L.; Benanti, A.; Frigeri, C.; Gadda, E.; Mantino, E.

A computerized real time data acquisition and data processing for the diagnosis of malfunctioning of steam turbogenerator systems is described. Pressure, vibration and temperature measurements are continuously collected from standard or special sensors including startup or stop events. The architecture of the monitoring system is detailed. Examples of the graphics output are presented. It is shown that such a system allows accurate diagnosis and the possibility of creating a data bank to describe the dynamic characteristics of the machine park.

Instrumented experiments aboard the frigate WOLF. Wolf 2: Measurement results of the 5.5 kg TNT in the crew aft sleeping compartment

NASA Astrophysics Data System (ADS)

Verhagen, T. L. A.; Vandekasteele, R. M.

1992-08-01

Within the framework of the research into the vulnerability of ships, an experimental investigation took place in 1989 aboard the frigate 'Wolf.' The recordings of an instrumented experiment in the crew aft sleeping compartment are presented. During this experiment, a nonfragmenting charge of 5.5 kg TNT was initiated. Preceding the 5.5 kg TNT experiment, a 2 kg TNT experiment was performed on the same day. Later that day the 15 kg TNT experiment took place. Reparation/modification of the instrumentation was not possible. The settings of the instrumentation equipment were based on the expected extreme responses of the 15 kg TNT experiment later that day which had, however, an influence on the signal to noise ratio. The blast measurements seem to have recorded correctly. The quasi static pressure in the experiment compartment as well as in the adjacent compartments showed classical behavior. The strain measurements seemed to be good, although some of them malfunctioned after a period of time.

40 CFR 63.1111 - Startup, shutdown, and malfunction.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 11 2013-07-01 2013-07-01 false Startup, shutdown, and malfunction. 63... Control Technology Standards § 63.1111 Startup, shutdown, and malfunction. (a) Startup, shutdown, and... develop a written startup, shutdown, and malfunction plan that describes, in detail, procedures for...

40 CFR 63.1111 - Startup, shutdown, and malfunction.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 11 2014-07-01 2014-07-01 false Startup, shutdown, and malfunction. 63... Control Technology Standards § 63.1111 Startup, shutdown, and malfunction. (a) Startup, shutdown, and... develop a written startup, shutdown, and malfunction plan that describes, in detail, procedures for...

40 CFR 63.1111 - Startup, shutdown, and malfunction.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 11 2012-07-01 2012-07-01 false Startup, shutdown, and malfunction. 63... Control Technology Standards § 63.1111 Startup, shutdown, and malfunction. (a) Startup, shutdown, and... develop a written startup, shutdown, and malfunction plan that describes, in detail, procedures for...

40 CFR 63.1111 - Startup, shutdown, and malfunction.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 10 2011-07-01 2011-07-01 false Startup, shutdown, and malfunction. 63... Control Technology Standards § 63.1111 Startup, shutdown, and malfunction. (a) Startup, shutdown, and... develop a written startup, shutdown, and malfunction plan that describes, in detail, procedures for...

Critical care nurses' experiences when technology malfunctions.

PubMed

Haghenbeck, Karen Toby

2005-01-01

When caring for critically ill patients, critical care nurses work with technology every day. Technology and equipment malfunctions can have a profound effect on nurses' practice and self-image. In this article, a descriptive phenomenological methodology was chosen to explicate the experience of seven critical care nurses. While participants realized that machines might malfunction, they experienced surprise, shock, and feelings of being "let down" and inadequate when malfunctions occurred. They questioned their competence and felt malfunctioning technology jeopardized their credibility and professional image. These findings are useful when structuring educational sessions on technology and in facilitating a supportive environment for critical care nurses when technology malfunctions.

Risk factors and possible mechanisms of superior vena cava intravenous port malfunction.

PubMed

Wu, Ching-Yang; Hu, Han-Chung; Ko, Po-Jen; Fu, Jui-Ying; Wu, Ching-Feng; Liu, Yun-Hen; Li, Hao-Jui; Kao, Tsung-Chi; Kao, Kuo-Chin; Yu, Sheng-Yueh; Chang, Chee-Jen; Hsieh, Hong-Chang

2012-05-01

To identify the risk factors leading to catheter malfunction. Reliable venous access is crucial for cancer patients. Malfunction of intravenous ports may lead to discontinuation of treatment and repeated interventions. We retrospectively reviewed the independent risk factors for catheter malfunction among patients receiving intravenous port implantations. A total of 1508 procedures were included from the calendar year 2006, and clinical data and chest plain films were analyzed. The patients were followed-up until June 30, 2010. For patients still alive, the last outpatient follow-up date was considered as the end point. For the remaining patients, the date of death or discharge against advice was considered as the end points. The risk factors for catheter malfunction were then evaluated. The intervention-free periods of the malfunction group and nonmalfunction group were 317 and 413 days, respectively. Statistical analyses showed that the Nut-Catheter Angle was the only risk factor for catheter malfunction (P = 0.001). A logistic model also confirmed that the Nut-Catheter Angle was the only risk factor for catheter malfunction (P < 0.001). Valve tip catheters were not advantageous with regard to catheter malfunction prevention as compared to open tip catheters. A smaller Nut-Catheter Angle had a greater risk for catheter malfunction. Catheter impingement caused by inadequate pocket creation and port implantation lead to compromised catheter lumen and difficulty flushing. The possibility of retained blood and medications increased thin thrombotic biofilm formation and medication precipitation. Catheter malfunctions can be avoided by using proper surgical techniques and adequate maintenance.

Clinical decision support alert malfunctions: analysis and empirically derived taxonomy.

PubMed

Wright, Adam; Ai, Angela; Ash, Joan; Wiesen, Jane F; Hickman, Thu-Trang T; Aaron, Skye; McEvoy, Dustin; Borkowsky, Shane; Dissanayake, Pavithra I; Embi, Peter; Galanter, William; Harper, Jeremy; Kassakian, Steve Z; Ramoni, Rachel; Schreiber, Richard; Sirajuddin, Anwar; Bates, David W; Sittig, Dean F

2018-05-01

To develop an empirically derived taxonomy of clinical decision support (CDS) alert malfunctions. We identified CDS alert malfunctions using a mix of qualitative and quantitative methods: (1) site visits with interviews of chief medical informatics officers, CDS developers, clinical leaders, and CDS end users; (2) surveys of chief medical informatics officers; (3) analysis of CDS firing rates; and (4) analysis of CDS overrides. We used a multi-round, manual, iterative card sort to develop a multi-axial, empirically derived taxonomy of CDS malfunctions. We analyzed 68 CDS alert malfunction cases from 14 sites across the United States with diverse electronic health record systems. Four primary axes emerged: the cause of the malfunction, its mode of discovery, when it began, and how it affected rule firing. Build errors, conceptualization errors, and the introduction of new concepts or terms were the most frequent causes. User reports were the predominant mode of discovery. Many malfunctions within our database caused rules to fire for patients for whom they should not have (false positives), but the reverse (false negatives) was also common. Across organizations and electronic health record systems, similar malfunction patterns recurred. Challenges included updates to code sets and values, software issues at the time of system upgrades, difficulties with migration of CDS content between computing environments, and the challenge of correctly conceptualizing and building CDS. CDS alert malfunctions are frequent. The empirically derived taxonomy formalizes the common recurring issues that cause these malfunctions, helping CDS developers anticipate and prevent CDS malfunctions before they occur or detect and resolve them expediently.

40 CFR 57.304 - Bypass, excess emissions and malfunctions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... malfunctions. 57.304 Section 57.304 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... limitation, as well as the operating data, documents, and calculations used in determining the magnitude of... malfunction (or an unavoidable start up and shut down resulting from a malfunction) and that: (1) The air...

40 CFR 57.304 - Bypass, excess emissions and malfunctions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... malfunctions. 57.304 Section 57.304 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... limitation, as well as the operating data, documents, and calculations used in determining the magnitude of... malfunction (or an unavoidable start up and shut down resulting from a malfunction) and that: (1) The air...

40 CFR 57.304 - Bypass, excess emissions and malfunctions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... malfunctions. 57.304 Section 57.304 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... limitation, as well as the operating data, documents, and calculations used in determining the magnitude of... malfunction (or an unavoidable start up and shut down resulting from a malfunction) and that: (1) The air...

40 CFR 57.304 - Bypass, excess emissions and malfunctions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... malfunctions. 57.304 Section 57.304 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... limitation, as well as the operating data, documents, and calculations used in determining the magnitude of... malfunction (or an unavoidable start up and shut down resulting from a malfunction) and that: (1) The air...

40 CFR 57.304 - Bypass, excess emissions and malfunctions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... malfunctions. 57.304 Section 57.304 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... limitation, as well as the operating data, documents, and calculations used in determining the magnitude of... malfunction (or an unavoidable start up and shut down resulting from a malfunction) and that: (1) The air...

Individualization and Needed Research.

ERIC Educational Resources Information Center

Ott, Jack M.; And Others

As has been the case in medicine, social work, and psychiatry, progress in education will follow closely the adequacy of our category system concerning pertinent functions of a child, our understanding of these functions, how children fail to function properly (malfunction), causes of malfunction, signs of malfunction, course of malfunction (time,…

40 CFR 63.762 - Startups, shutdowns, and malfunctions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 11 2012-07-01 2012-07-01 false Startups, shutdowns, and malfunctions... Facilities § 63.762 Startups, shutdowns, and malfunctions. (a) The provisions set forth in this subpart shall apply at all times except during startups or shutdowns, during malfunctions, and during periods of non...

40 CFR 63.762 - Startups, shutdowns, and malfunctions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 10 2010-07-01 2010-07-01 false Startups, shutdowns, and malfunctions... Facilities § 63.762 Startups, shutdowns, and malfunctions. (a) The provisions set forth in this subpart shall apply at all times except during startups or shutdowns, during malfunctions, and during periods of non...

40 CFR 63.1272 - Startups, shutdowns, and malfunctions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 11 2011-07-01 2011-07-01 false Startups, shutdowns, and malfunctions... Facilities § 63.1272 Startups, shutdowns, and malfunctions. (a) The provisions set forth in this subpart shall apply at all times except during startups or shutdowns, during malfunctions, and during periods of...

40 CFR 63.1272 - Startups, shutdowns, and malfunctions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 12 2012-07-01 2011-07-01 true Startups, shutdowns, and malfunctions... Facilities § 63.1272 Startups, shutdowns, and malfunctions. (a) The provisions set forth in this subpart shall apply at all times except during startups or shutdowns, during malfunctions, and during periods of...

40 CFR 63.762 - Startups, shutdowns, and malfunctions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 10 2011-07-01 2011-07-01 false Startups, shutdowns, and malfunctions... Facilities § 63.762 Startups, shutdowns, and malfunctions. (a) The provisions set forth in this subpart shall apply at all times except during startups or shutdowns, during malfunctions, and during periods of non...

40 CFR 63.1272 - Startups, shutdowns, and malfunctions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 11 2010-07-01 2010-07-01 true Startups, shutdowns, and malfunctions... Facilities § 63.1272 Startups, shutdowns, and malfunctions. (a) The provisions set forth in this subpart shall apply at all times except during startups or shutdowns, during malfunctions, and during periods of...

14 CFR 417.209 - Malfunction turn analysis.

Code of Federal Regulations, 2010 CFR

2010-01-01

... nozzle burn-through. For each cause of a malfunction turn, the analysis must establish the launch vehicle... the launch vehicle's turning capability in the event of a malfunction during flight. A malfunction... launch vehicle is capable. (4) The time, as a single value or a probability time distribution, when each...

14 CFR 417.209 - Malfunction turn analysis.

Code of Federal Regulations, 2011 CFR

2011-01-01

... nozzle burn-through. For each cause of a malfunction turn, the analysis must establish the launch vehicle... the launch vehicle's turning capability in the event of a malfunction during flight. A malfunction... launch vehicle is capable. (4) The time, as a single value or a probability time distribution, when each...

40 CFR 60.1710 - What happens to the emission limits during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2011 CFR

2011-07-01

... during periods of startup, shutdown, and malfunction? 60.1710 Section 60.1710 Protection of Environment... during periods of startup, shutdown, and malfunction? (a) The emission limits of this subpart apply at all times except during periods of municipal waste combustion unit startup, shutdown, or malfunction...

40 CFR 60.1220 - What happens to the emission limits during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2014 CFR

2014-07-01

... during periods of startup, shutdown, and malfunction? 60.1220 Section 60.1220 Protection of Environment... Emission Limits § 60.1220 What happens to the emission limits during periods of startup, shutdown, and... waste combustion unit startup, shutdown, or malfunction. (b) Each startup, shutdown, or malfunction must...

40 CFR 60.1220 - What happens to the emission limits during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2011 CFR

2011-07-01

... during periods of startup, shutdown, and malfunction? 60.1220 Section 60.1220 Protection of Environment... Emission Limits § 60.1220 What happens to the emission limits during periods of startup, shutdown, and... waste combustion unit startup, shutdown, or malfunction. (b) Each startup, shutdown, or malfunction must...

40 CFR 60.1220 - What happens to the emission limits during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2012 CFR

2012-07-01

... during periods of startup, shutdown, and malfunction? 60.1220 Section 60.1220 Protection of Environment... Emission Limits § 60.1220 What happens to the emission limits during periods of startup, shutdown, and... waste combustion unit startup, shutdown, or malfunction. (b) Each startup, shutdown, or malfunction must...

40 CFR 60.1220 - What happens to the emission limits during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2013 CFR

2013-07-01

... during periods of startup, shutdown, and malfunction? 60.1220 Section 60.1220 Protection of Environment... Emission Limits § 60.1220 What happens to the emission limits during periods of startup, shutdown, and... waste combustion unit startup, shutdown, or malfunction. (b) Each startup, shutdown, or malfunction must...

40 CFR 60.1220 - What happens to the emission limits during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2010 CFR

2010-07-01

... during periods of startup, shutdown, and malfunction? 60.1220 Section 60.1220 Protection of Environment... Emission Limits § 60.1220 What happens to the emission limits during periods of startup, shutdown, and... waste combustion unit startup, shutdown, or malfunction. (b) Each startup, shutdown, or malfunction must...

40 CFR 60.1710 - What happens to the emission limits during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2013 CFR

2013-07-01

... during periods of startup, shutdown, and malfunction? 60.1710 Section 60.1710 Protection of Environment... during periods of startup, shutdown, and malfunction? (a) The emission limits of this subpart apply at all times except during periods of municipal waste combustion unit startup, shutdown, or malfunction...

40 CFR 60.1710 - What happens to the emission limits during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2010 CFR

2010-07-01

... during periods of startup, shutdown, and malfunction? 60.1710 Section 60.1710 Protection of Environment... during periods of startup, shutdown, and malfunction? (a) The emission limits of this subpart apply at all times except during periods of municipal waste combustion unit startup, shutdown, or malfunction...

40 CFR 60.1710 - What happens to the emission limits during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2014 CFR

2014-07-01

... during periods of startup, shutdown, and malfunction? 60.1710 Section 60.1710 Protection of Environment... during periods of startup, shutdown, and malfunction? (a) The emission limits of this subpart apply at all times except during periods of municipal waste combustion unit startup, shutdown, or malfunction...

40 CFR 60.1710 - What happens to the emission limits during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2012 CFR

2012-07-01

... during periods of startup, shutdown, and malfunction? 60.1710 Section 60.1710 Protection of Environment... during periods of startup, shutdown, and malfunction? (a) The emission limits of this subpart apply at all times except during periods of municipal waste combustion unit startup, shutdown, or malfunction...

76 FR 39234 - Federal Acquisition Regulation; Unique Procurement Instrument Identifier

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-05

...-AL70 Federal Acquisition Regulation; Unique Procurement Instrument Identifier AGENCIES: Department of... Acquisition Regulation (FAR) to standardize use of unique Procurement Instrument Identifiers (PIID) throughout... Acquisition Council and the Defense Acquisition Regulations Council (the Councils) reviewed the public...

40 CFR 63.1344 - Affirmative defense for exceedance of emission limit during malfunction.

Code of Federal Regulations, 2012 CFR

2012-07-01

... in paragraph § 63.1343(b) you may assert an affirmative defense to a claim for civil penalties for... methods and engineering judgment, the amount of excess emissions that were the result of the malfunction... malfunction, if it wishes to avail itself of an affirmative defense to civil penalties for that malfunction...

40 CFR 63.1344 - Affirmative defense for exceedance of emission limit during malfunction.

Code of Federal Regulations, 2011 CFR

2011-07-01

... in paragraph § 63.1343(b) you may assert an affirmative defense to a claim for civil penalties for... methods and engineering judgment, the amount of excess emissions that were the result of the malfunction... malfunction, if it wishes to avail itself of an affirmative defense to civil penalties for that malfunction...

KU HAPLOINSUFFIENCY CAUSES A LYMPHOPROLIFERATIVE DISORDER OF IMMATURE T-CELL PRECURSORS DUE TO IKAROS MALFUNCTION

PubMed Central

Ozer, Zahide; Qazi, Sanjive; Ishkhanian, Rita; Hasty, Paul; Ma, Hong; Uckun, Fatih M.

2013-01-01

Ikaros (IK) malfunction has been implicated in the pathogenesis of acute lymphoblastic leukemia (ALL), the most common form of childhood cancer. Therefore, a stringent regulation of IK activity is very important. Here we provide unique genetic and biochemical evidence that the Ku protein components Ku70 and Ku80 act as positive regulators of IK function via formation of IK-Ku70 and IK-Ku80 heterodimers with augmented sequence-specific DNA binding activity. siRNA-mediated depletion of Ku70 or Ku80 reduced the sequence-specific DNA binding activity of IK in EMSA as well as the RT-PCR measured IK target gene expression levels in human cells. The interaction of Ku components with IK likely contributes to the anti-leukemic effects of IK as a tumor suppressor, because Ku70 as well as Ku80 haploinsuffiency in mice caused development of a lymphoproliferative disorder (LPD) involving CD2+CD4+CD8+CD1+IL7R+ thymic T-cell precursors with functional IK deficiency. PMID:24478815

Robotic equipment malfunction during robotic prostatectomy: a multi-institutional study.

PubMed

Lavery, Hugh J; Thaly, Rahul; Albala, David; Ahlering, Thomas; Shalhav, Arieh; Lee, David; Fagin, Randy; Wiklund, Peter; Dasgupta, Prokar; Costello, Anthony J; Tewari, Ashutosh; Coughlin, Geoff; Patel, Vipul R

2008-09-01

Robotic-assisted laparoscopic prostatectomy (RALP) is growing in popularity as a treatment option for prostate cancer. As a new technology, little is known regarding the reliability of the da Vinci robotic system. Intraoperative robotic equipment malfunction may force the surgeon to convert the procedure to an open or pure laparoscopic procedure, or possibly even abort the procedure. We report the first large-scale, multi-institutional review of robotic equipment malfunction. A questionnaire was designed to evaluate the rate of perioperative robotic malfunction during RALP. High-volume, experienced surgeons were asked to complete this evaluation based on the analysis of their data. Questions included the overall number of RALPs performed, the number of equipment malfunctions, the number of procedures that had to be converted or aborted, and the part of the robotic system that malfunctioned. Eleven institutions participated in the study with a median surgeon volume of 700 cases, accounting for a total case volume of 8240. Critical failure occurred in 34 cases (0.4%) leading to the cancellation of 24 cases prior to the procedure, and the conversion to two laparoscopic and eight open procedures. The most common components of the robot to malfunction were the arms and optical system. Critical robotic equipment malfunction is extremely rare in institutions that perform high volumes of RALPs, with a nonrecoverable malfunction rate of only 0.4%.

Simulation of Malfunctions for the ISS Double-Gimbal Control Moment Gyroscope

NASA Technical Reports Server (NTRS)

Inampudi, Ravi; Gordeuk, John

2016-01-01

This paper presents a simplified approach to simulation of malfunctions of the Control Moment Gyroscope (CMG) on board the International Space Station (ISS). These malfunctions will be used as part of flight training of CMG failure scenarios in the guidance navigation control (GNC) subsystem of the Training Systems for 21st Century (TS21) simulator. The CMG malfunctions are grouped under mechanical, thermal and electrical categories. A malfunction can be as simple as one which only affects the telemetry or a complex one that changes the state and behavior of the CMG model. In both cases, the ISS GNC flight software will read the telemetry and respond accordingly. The user executes these malfunctions by supplying conditional data which modify internal model states and then elicit a response as seen on the user displays. Ground operators and crew on board the ISS use CMG malfunction procedures to better understand and respond to anomalies observed within the CMG subsystem.

Results of an ISEE-1 experiment to study the interactions between energetic particles and discrete VLF waves in the magnetosphere

NASA Technical Reports Server (NTRS)

1980-01-01

Despite the malfunctioning of the digital portion of the experiment which is encoding the absolute amplitude of the wave spectrum with a fixed bias of approximately 20 dB, the analog portion of the instrument is acquiring excellent data concerning the wave function and relative amplitude. Results obtained over a 2-year period which have important implications for magnetospheric wave-particle interactions are examined in the areas of emission generation by nonconducted coherent waves, and cold plasma distribution in the inner magnetosphere.

Develop advanced nonlinear signal analysis topographical mapping system

NASA Technical Reports Server (NTRS)

Jong, Jen-Yi

1993-01-01

This study will provide timely assessment of SSME component operational status, identify probable causes of malfunction, and indicate feasible engineering solutions. The final result of this program will yield an advanced nonlinear signal analysis topographical mapping system (ATMS) of nonlinear and nonstationary spectral analysis software package integrated with the Compressed SSME TOPO Data Base (CSTDB) on the same platform. This system will allow NASA engineers to retrieve any unique defect signatures and trends associated with different failure modes and anomalous phenomena over the entire SSME test history across turbopump families.

Ovarian hyperstimulation syndrome leading to ventriculoperitoneal shunt malfunction: Case report.

PubMed

Azriel, Amit; Fleming, Benjamin; Dior, Uri P; Moscovici, Samuel; Sufaro, Yuval; Awad, Mohammed; Drummond, Kate

2018-06-01

Ventriculoperitoneal shunt (VPS) insertion is a common neurosurgical procedure for hydrocephalus. Unfortunately, VPS malfunction is not uncommon, with an estimated cumulative rate of 32% at 5 years. As flow through the shunt is influenced by the pressure gradient between the ventricles and the peritoneal cavity, malfunction may be caused by elevated intra-abdominal pressure. We present a rare patient with ascites following ovarian hyperstimulation syndrome (OHSS) leading to shunt malfunction. OHSS is a potentially life-threatening complication of controlled ovarian stimulation caused by the administration of exogenous gonadotropins. In this patient clinical and radiological resolution of shunt dysfunction were achieved following peritoneocentesis. To our knowledge this is the first described case of OHSS leading to shunt malfunction, emphasizing the importance of awareness, early recognition and proper management of abdominal etiologies of VPS malfunction. Copyright © 2018 Elsevier Ltd. All rights reserved.

Optical pre-screening in breast screening programs: Can we identify women who benefit most from limited mammography resources?

NASA Astrophysics Data System (ADS)

Walter, Jane; Loshchenov, Maxim; Zhilkin, Vladimir; Peake, Rachel; Stone, Jennifer; Lilge, Lothar

2017-04-01

Background: In excess of 60% of all cancers are detected in low and middle-income countries, with breast cancer (BC) the dominant malignancy for women. Incidence rates continue to climb, most noticeably in the less than 50-year-old population. Expansion of mammography infrastructure and resources is lacking, resulting in over 60% of women diagnosed with stage III/IV BC in the majority of these countries. Optical Breast Spectroscopy (OBS) was shown to correlate well with mammographic breast density (MBD). OBS could aid breast screening programs in low- and middle-income countries by lowering the number of mammographs required for complete population coverage. However, its performance needs to be tested in large population trails to ensure high sensitivity and acceptable specificity. Methods: For the planned studies in low- and middle-income countries in different continents, online methods need to be implemented to monitor the performance and data collection by these devices, operated by trained nurses. Based on existing datasets, procedures were developed to validate an individual woman's data integrity and to identify operator errors versus system malfunctions. Results: Using a dataset comprising spectra from 360 women collected by 2 instruments in different locations and with 3 different trained operators, automated methods were developed to identify 100% of the source or photodetector malfunctions as well as incorrect calibrations and 96% of instances of insufficient tissue contact. Conclusions: Implementing the dataset validation locally in each instrument and tethered to a cloud database will allow the planned clinical trials to proceed.

40 CFR 63.1344 - Affirmative defense for violation of emission standards during malfunction.

Code of Federal Regulations, 2013 CFR

2013-07-01

... defense to a claim for civil penalties for violations of such standards that are caused by malfunction, as... malfunction event at issue. The analysis shall also specify, using best monitoring methods and engineering...

40 CFR 63.1344 - Affirmative defense for violation of emission standards during malfunction.

Code of Federal Regulations, 2014 CFR

2014-07-01

... defense to a claim for civil penalties for violations of such standards that are caused by malfunction, as... malfunction event at issue. The analysis shall also specify, using best monitoring methods and engineering...

The detection of dissolved gases in transformer oil by gas chromatography with helium ionization detector

NASA Astrophysics Data System (ADS)

Deng, Xian-qin; Fang, Hua; Li, Min-xian

2017-07-01

The GC-PDD with the technology of valve cutting and helium ionization detector was used to analyze the dissolved gases in ultra-high voltage(UHV) and extra-high voltage(EHV) transformer oil. The detection limit(DL) reached ppb grade, especially for the featuring gas—C2H2 and H2, whose DL could reach 5ppb and 11ppb respectively. The test reproducibility of the instrument was about 1% and the correlation coefficient of standard curve-r is greater or equal to 0.99, which showed obvious advantage compared with normal GC. In addition, the auxiliary gas of H2 was not used in this instrument, which completely improved the safety performance. Thus, the application of GC-PDD has significant meaning in warning potential malfunction inside the ultra-high voltage transformer in advance.

Effects of a malfunctional column on conventional and FeedCol-simulated moving bed chromatography performance.

PubMed

Song, Ji-Yeon; Oh, Donghoon; Lee, Chang-Ha

2015-07-17

The effects of a malfunctional column on the performance of a simulated moving bed (SMB) process were studied experimentally and theoretically. The experimental results of conventional four-zone SMB (2-2-2-2 configuration) and FeedCol operation (2-2-2-2 configuration with one feed column) with one malfunctional column were compared with simulation results of the corresponding SMB processes with a normal column configuration. The malfunctional column in SMB processes significantly deteriorated raffinate purity. However, the extract purity was equivalent or slightly improved compared with the corresponding normal SMB operation because the complete separation zone of the malfunctional column moved to a lower flow rate range in zones II and III. With the malfunctional column configuration, FeedCol operation gave better experimental performance (up to 7%) than conventional SMB operation because controlling product purity with FeedCol operation was more flexible through the use of two additional operating variables, injection time and injection length. Thus, compared with conventional SMB separation, extract with equivalent or slightly better purity could be produced from FeedCol operation even with a malfunctional column, while minimizing the decrease in raffinate purity (less than 2%). Copyright © 2015 Elsevier B.V. All rights reserved.

40 CFR 63.1354 - Reporting requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... operator during a startup, shutdown, or malfunction of an affected source (including actions taken to correct a malfunction) are consistent with the procedures specified in the source's startup, shutdown, and... report. Reports shall only be required if a startup, shutdown, or malfunction occurred during the...

40 CFR 63.1354 - Reporting requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... owner or operator during a startup, shutdown, or malfunction of an affected source (including actions taken to correct a malfunction) are consistent with the procedures specified in the source's startup... information in a semiannual report. Reports shall only be required if a startup, shutdown, or malfunction...

40 CFR 52.1183 - Visibility protection.

Code of Federal Regulations, 2013 CFR

2013-07-01

... excess emissions that occurs during startups, shutdowns, and malfunctions of the unit, the nature and... that occurs during startups, shutdowns, and malfunctions of the unit, the nature and cause of any... startup, shutdown, and malfunction. (viii) All CEMS required by this section must meet the minimum data...

40 CFR 63.1111 - Startup, shutdown, and malfunction.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 10 2010-07-01 2010-07-01 false Startup, shutdown, and malfunction. 63.1111 Section 63.1111 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... Control Technology Standards § 63.1111 Startup, shutdown, and malfunction. (a) Startup, shutdown, and...

Insulin Pump Malfunction During Hospitalization: Two Case Reports.

PubMed

Faulds, Eileen R; Wyne, Kathleen L; Buschur, Elizabeth O; McDaniel, Jodi; Dungan, Kathleen

2016-06-01

Insulin pump malfunctions and failures continue to occur; however, more severe malfunctions such as the "runaway pump" phenomenon are rarely reported. This article describes two cases of pump malfunction in which pump users appear to have received an unsolicited bolus of insulin resulting in severe episodes of hypoglycemia during hospitalization. Both cases of insulin pump malfunction occurred in the inpatient setting at a large academic medical center in the United States. An analysis of the corresponding insulin pump downloads was performed. The Food and Drug Administration's (FDA's) Manufacturer and User Facility Device Experience (MAUDE) database was searched for similar cases involving Medtronic (Northridge, CA) insulin pumps using the terms "pump," "infusion," "insulin AND malfunction AND Medtronic." The two cases described show remarkable similarities, each demonstrating a severe hypoglycemic event preceded by an infusion site change followed by an alarm. In both cases a rapid spraying of insulin was reported. The insulin pump downloads validated much of the patients' and medical staff's descriptions of events. The FDA's MAUDE database search revealed 425 cases meeting our search term criteria. All cases were reviewed. Seven cases were identified involving independent movement of the reservoir piston. The cases detailed are the first to describe an insulin pump malfunction of this nature in the hospital setting involving unsolicited insulin boluses leading to severe hypoglycemia. The cases are particularly compelling in that they were witnessed by medical personnel. Providers and patients should receive instruction education on the recognition and management of insulin pump malfunction.

The vexing problem of thrombosis in long-term mechanical circulatory support.

PubMed

Mehra, Mandeep R; Stewart, Garrick C; Uber, Patricia A

2014-01-01

Durable left ventricular assist devices (LVADs) have not only enhanced longevity but also conferred sustained improvements in quality of life, symptom control, and functional capacity in patients with medically refractory advanced heart failure. Problems with device-related infection, bleeding, neurologic events, right-sided heart failure, and device malfunction have dominated the clinical care of patients living on mechanical support. Even as adoption of durable LVADs accelerated globally, we began to encounter a growing dilemma of pump malfunction caused by thrombosis. In early 2011, clinicians began to notice a spike in the incidence of pump thrombosis with the HeartMate II (Thoratec Corp, Pleasanton, CA) LVAD. By 2012, the problem of thrombosis in LVADs began to consume most of the scientific direction as centers and collaborative groups began to dissect this nascent phenomenon. In this perspective, we describe the magnitude and implications of pump thrombosis, discuss secular and management trends in this unique population, attempt to dissect the problem at its root, offer guidance on surveillance and therapeutic principles, and outline issues that deserve our immediate and collaborative attention. © 2014 International Society for Heart and Lung Transplantation Published by International Society for the Heart and Lung Transplantation All rights reserved.

14 CFR 21.3 - Reporting of failures, malfunctions, and defects.

Code of Federal Regulations, 2014 CFR

2014-01-01

... crew compartment or passenger cabin. (4) A malfunction, failure, or defect of a propeller control... structural or flight control system malfunction, defect, or failure which causes an interference with normal control of the aircraft for which derogates the flying qualities. (12) A complete loss of more than one...

14 CFR 21.3 - Reporting of failures, malfunctions, and defects.

Code of Federal Regulations, 2013 CFR

2013-01-01

... crew compartment or passenger cabin. (4) A malfunction, failure, or defect of a propeller control... structural or flight control system malfunction, defect, or failure which causes an interference with normal control of the aircraft for which derogates the flying qualities. (12) A complete loss of more than one...

14 CFR 21.3 - Reporting of failures, malfunctions, and defects.

Code of Federal Regulations, 2012 CFR

2012-01-01

... crew compartment or passenger cabin. (4) A malfunction, failure, or defect of a propeller control... structural or flight control system malfunction, defect, or failure which causes an interference with normal control of the aircraft for which derogates the flying qualities. (12) A complete loss of more than one...

40 CFR 270.235 - Options for incinerators, cement kilns, lightweight aggregate kilns, solid fuel boilers, liquid...

Code of Federal Regulations, 2014 CFR

2014-07-01

... to minimize emissions from startup, shutdown, and malfunction events. 270.235 Section 270.235... from startup, shutdown, and malfunction events. (a) Facilities with existing permits—(1) Revisions to... from startup, shutdown, and malfunction events under any of the following options when requesting...

40 CFR 270.235 - Options for incinerators, cement kilns, lightweight aggregate kilns, solid fuel boilers, liquid...

Code of Federal Regulations, 2012 CFR

2012-07-01

... to minimize emissions from startup, shutdown, and malfunction events. 270.235 Section 270.235... from startup, shutdown, and malfunction events. (a) Facilities with existing permits—(1) Revisions to... from startup, shutdown, and malfunction events under any of the following options when requesting...

40 CFR 270.235 - Options for incinerators, cement kilns, lightweight aggregate kilns, solid fuel boilers, liquid...

Code of Federal Regulations, 2011 CFR

2011-07-01

... to minimize emissions from startup, shutdown, and malfunction events. 270.235 Section 270.235... from startup, shutdown, and malfunction events. (a) Facilities with existing permits—(1) Revisions to... from startup, shutdown, and malfunction events under any of the following options when requesting...

40 CFR 270.235 - Options for incinerators, cement kilns, lightweight aggregate kilns, solid fuel boilers, liquid...

Code of Federal Regulations, 2013 CFR

2013-07-01

... to minimize emissions from startup, shutdown, and malfunction events. 270.235 Section 270.235... from startup, shutdown, and malfunction events. (a) Facilities with existing permits—(1) Revisions to... from startup, shutdown, and malfunction events under any of the following options when requesting...

40 CFR 63.8615 - How do I monitor and collect data to demonstrate continuous compliance?

Code of Federal Regulations, 2010 CFR

2010-07-01

... monitoring malfunctions, associated repairs, out-of-control periods, or required quality assurance or control activities for purposes of calculating data averages. A monitoring malfunction is any sudden, infrequent, not... periods of monitor malfunctions, associated repairs, and required quality assurance or control activities...

40 CFR 52.271 - Malfunction, startup, and shutdown regulations.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Malfunction, startup, and shutdown regulations. 52.271 Section 52.271 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.271 Malfunction, startup, and shutdown regulations. (a)...

40 CFR 52.271 - Malfunction, startup, and shutdown regulations.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 3 2011-07-01 2011-07-01 false Malfunction, startup, and shutdown regulations. 52.271 Section 52.271 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.271 Malfunction, startup, and shutdown regulations. (a)...

40 CFR 52.271 - Malfunction, startup, and shutdown regulations.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Malfunction, startup, and shutdown regulations. 52.271 Section 52.271 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.271 Malfunction, startup, and shutdown regulations. (a)...

40 CFR 52.271 - Malfunction, startup, and shutdown regulations.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Malfunction, startup, and shutdown regulations. 52.271 Section 52.271 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.271 Malfunction, startup, and shutdown regulations. (a)...

40 CFR 52.271 - Malfunction, startup, and shutdown regulations.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Malfunction, startup, and shutdown regulations. 52.271 Section 52.271 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.271 Malfunction, startup, and shutdown regulations. (a)...

75 FR 34192 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing and Immediate Effectiveness of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-16

... erroneous trades occurring from disruptions and/or malfunctions of Exchange systems. The changes described... disruptions and malfunctions. Specifically, the Exchange proposes to include ``verifiable systems disruptions... modification of transactions that resulted from verifiable disruptions and/or malfunctions of Exchanges systems...

40 CFR 65.6 - Startup, shutdown, and malfunction plan and procedures.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 15 2011-07-01 2011-07-01 false Startup, shutdown, and malfunction... (CONTINUED) AIR PROGRAMS (CONTINUED) CONSOLIDATED FEDERAL AIR RULE General Provisions § 65.6 Startup... Group 2A or Group 2B process vents. (b) Startup, shutdown, and malfunction plan—(1) Description and...

40 CFR 65.6 - Startup, shutdown, and malfunction plan and procedures.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 15 2010-07-01 2010-07-01 false Startup, shutdown, and malfunction... (CONTINUED) AIR PROGRAMS (CONTINUED) CONSOLIDATED FEDERAL AIR RULE General Provisions § 65.6 Startup... Group 2A or Group 2B process vents. (b) Startup, shutdown, and malfunction plan—(1) Description and...

40 CFR 65.6 - Startup, shutdown, and malfunction plan and procedures.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 16 2014-07-01 2014-07-01 false Startup, shutdown, and malfunction... (CONTINUED) AIR PROGRAMS (CONTINUED) CONSOLIDATED FEDERAL AIR RULE General Provisions § 65.6 Startup... Group 2A or Group 2B process vents. (b) Startup, shutdown, and malfunction plan—(1) Description and...

40 CFR 60.3025 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false What happens during periods of startup... during periods of startup, shutdown, and malfunction? The emission limitations and operating limits apply at all times except during OSWI unit startups, shutdowns, or malfunctions. Model Rule—Performance...

40 CFR 60.3025 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 7 2014-07-01 2014-07-01 false What happens during periods of startup... during periods of startup, shutdown, and malfunction? The emission limitations and operating limits apply at all times except during OSWI unit startups, shutdowns, or malfunctions. Model Rule—Performance...

40 CFR Table 15 to Subpart Xxxx of... - Requirements for Reports

Code of Federal Regulations, 2011 CFR

2011-07-01

... had a startup, shutdown or malfunction during the reporting period and you took actions consistent with your startup, shutdown, and malfunction plan, the compliance report must include the information... requirements for annual reporting in § 63.6010(f). 2. Immediate startup, shutdown, and malfunction report if...

40 CFR 65.6 - Startup, shutdown, and malfunction plan and procedures.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 16 2012-07-01 2012-07-01 false Startup, shutdown, and malfunction... (CONTINUED) AIR PROGRAMS (CONTINUED) CONSOLIDATED FEDERAL AIR RULE General Provisions § 65.6 Startup... Group 2A or Group 2B process vents. (b) Startup, shutdown, and malfunction plan—(1) Description and...

40 CFR 65.6 - Startup, shutdown, and malfunction plan and procedures.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 16 2013-07-01 2013-07-01 false Startup, shutdown, and malfunction... (CONTINUED) AIR PROGRAMS (CONTINUED) CONSOLIDATED FEDERAL AIR RULE General Provisions § 65.6 Startup... Group 2A or Group 2B process vents. (b) Startup, shutdown, and malfunction plan—(1) Description and...

40 CFR 60.2918 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 6 2011-07-01 2011-07-01 false What happens during periods of startup... of startup, shutdown, and malfunction? The emission limitations and operating limits apply at all times except during OSWI unit startups, shutdowns, or malfunctions. Performance Testing ...

40 CFR 60.2918 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false What happens during periods of startup... of startup, shutdown, and malfunction? The emission limitations and operating limits apply at all times except during OSWI unit startups, shutdowns, or malfunctions. Performance Testing ...

40 CFR 60.2918 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 7 2012-07-01 2012-07-01 false What happens during periods of startup... of startup, shutdown, and malfunction? The emission limitations and operating limits apply at all times except during OSWI unit startups, shutdowns, or malfunctions. Performance Testing ...

40 CFR 60.3025 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 7 2012-07-01 2012-07-01 false What happens during periods of startup... during periods of startup, shutdown, and malfunction? The emission limitations and operating limits apply at all times except during OSWI unit startups, shutdowns, or malfunctions. Model Rule—Performance...

40 CFR 60.3025 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 7 2013-07-01 2013-07-01 false What happens during periods of startup... during periods of startup, shutdown, and malfunction? The emission limitations and operating limits apply at all times except during OSWI unit startups, shutdowns, or malfunctions. Model Rule—Performance...

40 CFR 60.3025 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 6 2011-07-01 2011-07-01 false What happens during periods of startup... during periods of startup, shutdown, and malfunction? The emission limitations and operating limits apply at all times except during OSWI unit startups, shutdowns, or malfunctions. Model Rule—Performance...

40 CFR 63.1367 - Recordkeeping requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) of subpart A of this part. (3) Startup, shutdown, and malfunction plan. The owner or operator of an affected source shall develop a written startup, shutdown, and malfunction plan as specified in § 63.6(e)(3... during periods of startup, shutdown, and malfunction and a program for corrective action for a...

40 CFR 66.33 - De Minimis exemptions: malfunctions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 15 2011-07-01 2011-07-01 false De Minimis exemptions: malfunctions...; Revocation of Exemptions § 66.33 De Minimis exemptions: malfunctions. (a) The Administrator may, upon notice... respect to a particular instance of noncompliance, that such noncompliance was de minimis in nature and...

40 CFR 66.33 - De Minimis exemptions: malfunctions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 15 2010-07-01 2010-07-01 false De Minimis exemptions: malfunctions...; Revocation of Exemptions § 66.33 De Minimis exemptions: malfunctions. (a) The Administrator may, upon notice... respect to a particular instance of noncompliance, that such noncompliance was de minimis in nature and...

40 CFR 63.1367 - Recordkeeping requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., and malfunction and a program for corrective action for a malfunctioning process, air pollution... duration of each malfunction of the process operations or of air pollution control equipment used to comply... explanation of the cause of the alarm and the corrective action taken. (6) The owner or operator of an...

40 CFR 63.102 - General standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... in § 63.101 of this subpart), malfunction, or non-operation of the chemical manufacturing process... subpart G of this part apply. However, if a start-up, shutdown, malfunction or period of non-operation of... part during the start-up, shutdown, malfunction or period of non-operation. For example, if there is an...

40 CFR 63.1551 - Affirmative defense for exceedance of emission limit during malfunction.

Code of Federal Regulations, 2014 CFR

2014-07-01

... affirmative defense to a claim for civil penalties for exceedances of such standards that are caused by... malfunction event at issue. The analysis shall also specify, using best monitoring methods and engineering... avail itself of an affirmative defense to civil penalties for that malfunction. The owner or operator...

40 CFR 63.1551 - Affirmative defense for exceedance of emission limit during malfunction.

Code of Federal Regulations, 2013 CFR

2013-07-01

... affirmative defense to a claim for civil penalties for exceedances of such standards that are caused by... malfunction event at issue. The analysis shall also specify, using best monitoring methods and engineering... avail itself of an affirmative defense to civil penalties for that malfunction. The owner or operator...

30 CFR 75.1714-8 - Reporting SCSR inventory and malfunctions; retention of SCSRs.

Code of Federal Regulations, 2010 CFR

2010-07-01

... submit the inventory within 3 months of beginning operation. (1) The inventory shall include— (i) Mine... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Reporting SCSR inventory and malfunctions... Miscellaneous § 75.1714-8 Reporting SCSR inventory and malfunctions; retention of SCSRs. (a) SCSR inventory. A...

40 CFR 62.15150 - What happens to the operating requirements during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2013 CFR

2013-07-01

... requirements during periods of startup, shutdown, and malfunction? 62.15150 Section 62.15150 Protection of... § 62.15150 What happens to the operating requirements during periods of startup, shutdown, and... municipal waste combustion unit startup, shutdown, or malfunction. (b) Each startup, shutdown, or...

40 CFR Table 7 to Subpart Aaaaa of... - Requirements for Reports

Code of Federal Regulations, 2011 CFR

2011-07-01

.... If you had a startup, shutdown or malfunction during the reporting period and you took actions...) Semiannually according to the requirements in § 63.7131(b). 2. An immediate startup, shutdown, and malfunction report if you had a startup, shutdown, or malfunction during the reporting period that is not consistent...

40 CFR Table 7 to Subpart Aaaaa of... - Requirements for Reports

Code of Federal Regulations, 2012 CFR

2012-07-01

.... If you had a startup, shutdown or malfunction during the reporting period and you took actions...) Semiannually according to the requirements in § 63.7131(b). 2. An immediate startup, shutdown, and malfunction report if you had a startup, shutdown, or malfunction during the reporting period that is not consistent...

40 CFR 62.15165 - What happens to the emission limits during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2014 CFR

2014-07-01

... during periods of startup, shutdown, and malfunction? 62.15165 Section 62.15165 Protection of Environment... emission limits during periods of startup, shutdown, and malfunction? (a) The emission limits of this subpart apply at all times except during periods of municipal waste combustion unit startup, shutdown, or...

40 CFR Table 7 to Subpart Aaaaa of... - Requirements for Reports

Code of Federal Regulations, 2010 CFR

2010-07-01

.... If you had a startup, shutdown or malfunction during the reporting period and you took actions...) Semiannually according to the requirements in § 63.7131(b). 2. An immediate startup, shutdown, and malfunction report if you had a startup, shutdown, or malfunction during the reporting period that is not consistent...

40 CFR 60.2685 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false What happens during periods of startup... happens during periods of startup, shutdown, and malfunction? (a) The emission limitations and operating limits apply at all times except during CISWI unit startups, shutdowns, or malfunctions. (b) Each...

40 CFR 62.15150 - What happens to the operating requirements during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2012 CFR

2012-07-01

... requirements during periods of startup, shutdown, and malfunction? 62.15150 Section 62.15150 Protection of... § 62.15150 What happens to the operating requirements during periods of startup, shutdown, and... municipal waste combustion unit startup, shutdown, or malfunction. (b) Each startup, shutdown, or...

40 CFR 60.1695 - What happens to the operating requirements during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2012 CFR

2012-07-01

... requirements during periods of startup, shutdown, and malfunction? 60.1695 Section 60.1695 Protection of... Requirements § 60.1695 What happens to the operating requirements during periods of startup, shutdown, and... municipal waste combustion unit startup, shutdown, or malfunction. (b) Each startup, shutdown, or...

40 CFR 63.1570 - What are my general requirements for complying with this subpart?

Code of Federal Regulations, 2013 CFR

2013-07-01

... control equipment. (d) You must develop a written startup, shutdown, and malfunction plan (SSMP) according... includes periods of startup, shutdown, and malfunction. You also must report each instance in which you did...), deviations that occur during a period of startup, shutdown, or malfunction are not violations if you...

40 CFR 60.2685 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 6 2011-07-01 2011-07-01 false What happens during periods of startup... happens during periods of startup, shutdown, and malfunction? (a) The emission limitations and operating limits apply at all times except during CISWI unit startups, shutdowns, or malfunctions. (b) Each...

40 CFR 62.15150 - What happens to the operating requirements during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2011 CFR

2011-07-01

... requirements during periods of startup, shutdown, and malfunction? 62.15150 Section 62.15150 Protection of... § 62.15150 What happens to the operating requirements during periods of startup, shutdown, and... municipal waste combustion unit startup, shutdown, or malfunction. (b) Each startup, shutdown, or...

40 CFR 60.1205 - What happens to the operating requirements during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2011 CFR

2011-07-01

... requirements during periods of startup, shutdown, and malfunction? 60.1205 Section 60.1205 Protection of... requirements during periods of startup, shutdown, and malfunction? (a) The operating requirements of this subpart apply at all times except during periods of municipal waste combustion unit startup, shutdown, or...

40 CFR 63.5555 - How do I demonstrate continuous compliance with the emission limits, operating limits, and work...

Code of Federal Regulations, 2011 CFR

2011-07-01

... startup, shutdown, and malfunction. These instances are deviations from the emission limits, operating... during a period of startup, shutdown, or malfunction are not violations if you demonstrate to the... determine whether deviations that occur during a period you identify as a startup, shutdown, or malfunction...

40 CFR 62.15165 - What happens to the emission limits during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2011 CFR

2011-07-01

... during periods of startup, shutdown, and malfunction? 62.15165 Section 62.15165 Protection of Environment... emission limits during periods of startup, shutdown, and malfunction? (a) The emission limits of this subpart apply at all times except during periods of municipal waste combustion unit startup, shutdown, or...

40 CFR 62.15150 - What happens to the operating requirements during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2010 CFR

2010-07-01

... requirements during periods of startup, shutdown, and malfunction? 62.15150 Section 62.15150 Protection of... § 62.15150 What happens to the operating requirements during periods of startup, shutdown, and... municipal waste combustion unit startup, shutdown, or malfunction. (b) Each startup, shutdown, or...

40 CFR 60.1205 - What happens to the operating requirements during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2010 CFR

2010-07-01

... requirements during periods of startup, shutdown, and malfunction? 60.1205 Section 60.1205 Protection of... requirements during periods of startup, shutdown, and malfunction? (a) The operating requirements of this subpart apply at all times except during periods of municipal waste combustion unit startup, shutdown, or...

40 CFR 62.15165 - What happens to the emission limits during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2012 CFR

2012-07-01

... during periods of startup, shutdown, and malfunction? 62.15165 Section 62.15165 Protection of Environment... emission limits during periods of startup, shutdown, and malfunction? (a) The emission limits of this subpart apply at all times except during periods of municipal waste combustion unit startup, shutdown, or...

40 CFR 60.2120 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false What happens during periods of startup... 1, 2001 Emission Limitations and Operating Limits § 60.2120 What happens during periods of startup... during CISWI unit startups, shutdowns, or malfunctions. (b) Each malfunction must last no longer than 3...

40 CFR 63.9040 - How do I demonstrate continuous compliance with the emission limitations and work practice...

Code of Federal Regulations, 2011 CFR

2011-07-01

... to you. This includes periods of startup, shutdown, and malfunction. These instances are deviations... during a period of startup, shutdown, or malfunction are not violations if you demonstrate to the... determine whether deviations that occur during a period of startup, shutdown, or malfunction are violations...

40 CFR Table 7 to Subpart Aaaaa of... - Requirements for Reports

Code of Federal Regulations, 2013 CFR

2013-07-01

.... If you had a startup, shutdown or malfunction during the reporting period and you took actions...) Semiannually according to the requirements in § 63.7131(b). 2. An immediate startup, shutdown, and malfunction report if you had a startup, shutdown, or malfunction during the reporting period that is not consistent...

40 CFR 63.5555 - How do I demonstrate continuous compliance with the emission limits, operating limits, and work...

Code of Federal Regulations, 2010 CFR

2010-07-01

... startup, shutdown, and malfunction. These instances are deviations from the emission limits, operating... during a period of startup, shutdown, or malfunction are not violations if you demonstrate to the... determine whether deviations that occur during a period you identify as a startup, shutdown, or malfunction...

40 CFR 60.1695 - What happens to the operating requirements during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2011 CFR

2011-07-01

... requirements during periods of startup, shutdown, and malfunction? 60.1695 Section 60.1695 Protection of... Requirements § 60.1695 What happens to the operating requirements during periods of startup, shutdown, and... municipal waste combustion unit startup, shutdown, or malfunction. (b) Each startup, shutdown, or...

40 CFR 63.1570 - What are my general requirements for complying with this subpart?

Code of Federal Regulations, 2014 CFR

2014-07-01

... control equipment. (d) You must develop a written startup, shutdown, and malfunction plan (SSMP) according... includes periods of startup, shutdown, and malfunction. You also must report each instance in which you did...), deviations that occur during a period of startup, shutdown, or malfunction are not violations if you...

40 CFR 63.1570 - What are my general requirements for complying with this subpart?

Code of Federal Regulations, 2010 CFR

2010-07-01

... control equipment. (d) You must develop a written startup, shutdown, and malfunction plan (SSMP) according... includes periods of startup, shutdown, and malfunction. You also must report each instance in which you did...), deviations that occur during a period of startup, shutdown, or malfunction are not violations if you...

40 CFR 60.2685 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 7 2012-07-01 2012-07-01 false What happens during periods of startup...-Emission Limitations and Operating Limits § 60.2685 What happens during periods of startup, shutdown, and... startups, shutdowns, or malfunctions. (b) Each malfunction must last no longer than 3 hours. Effective Date...

40 CFR 60.1205 - What happens to the operating requirements during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2012 CFR

2012-07-01

... requirements during periods of startup, shutdown, and malfunction? 60.1205 Section 60.1205 Protection of... requirements during periods of startup, shutdown, and malfunction? (a) The operating requirements of this subpart apply at all times except during periods of municipal waste combustion unit startup, shutdown, or...

40 CFR 60.2120 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 6 2011-07-01 2011-07-01 false What happens during periods of startup... 1, 2001 Emission Limitations and Operating Limits § 60.2120 What happens during periods of startup... during CISWI unit startups, shutdowns, or malfunctions. (b) Each malfunction must last no longer than 3...

40 CFR Table 7 to Subpart Aaaaa of... - Requirements for Reports

Code of Federal Regulations, 2014 CFR

2014-07-01

.... If you had a startup, shutdown or malfunction during the reporting period and you took actions...) Semiannually according to the requirements in § 63.7131(b). 2. An immediate startup, shutdown, and malfunction report if you had a startup, shutdown, or malfunction during the reporting period that is not consistent...

40 CFR 63.1570 - What are my general requirements for complying with this subpart?

Code of Federal Regulations, 2011 CFR

2011-07-01

... control equipment. (d) You must develop a written startup, shutdown, and malfunction plan (SSMP) according... includes periods of startup, shutdown, and malfunction. You also must report each instance in which you did...), deviations that occur during a period of startup, shutdown, or malfunction are not violations if you...

40 CFR 60.2120 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 7 2012-07-01 2012-07-01 false What happens during periods of startup... 1, 2001 Emission Limitations and Operating Limits § 60.2120 What happens during periods of startup... during CISWI unit startups, shutdowns, or malfunctions. (b) Each malfunction must last no longer than 3...

40 CFR 62.15165 - What happens to the emission limits during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2013 CFR

2013-07-01

... during periods of startup, shutdown, and malfunction? 62.15165 Section 62.15165 Protection of Environment... emission limits during periods of startup, shutdown, and malfunction? (a) The emission limits of this subpart apply at all times except during periods of municipal waste combustion unit startup, shutdown, or...

40 CFR 60.1205 - What happens to the operating requirements during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2014 CFR

2014-07-01

... requirements during periods of startup, shutdown, and malfunction? 60.1205 Section 60.1205 Protection of... requirements during periods of startup, shutdown, and malfunction? (a) The operating requirements of this subpart apply at all times except during periods of municipal waste combustion unit startup, shutdown, or...

40 CFR 63.1570 - What are my general requirements for complying with this subpart?

Code of Federal Regulations, 2012 CFR

2012-07-01

... control equipment. (d) You must develop a written startup, shutdown, and malfunction plan (SSMP) according... includes periods of startup, shutdown, and malfunction. You also must report each instance in which you did...), deviations that occur during a period of startup, shutdown, or malfunction are not violations if you...

40 CFR 60.1695 - What happens to the operating requirements during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2014 CFR

2014-07-01

... requirements during periods of startup, shutdown, and malfunction? 60.1695 Section 60.1695 Protection of... Requirements § 60.1695 What happens to the operating requirements during periods of startup, shutdown, and... municipal waste combustion unit startup, shutdown, or malfunction. (b) Each startup, shutdown, or...

40 CFR 60.1695 - What happens to the operating requirements during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2010 CFR

2010-07-01

... requirements during periods of startup, shutdown, and malfunction? 60.1695 Section 60.1695 Protection of... Requirements § 60.1695 What happens to the operating requirements during periods of startup, shutdown, and... municipal waste combustion unit startup, shutdown, or malfunction. (b) Each startup, shutdown, or...

40 CFR 62.15165 - What happens to the emission limits during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2010 CFR

2010-07-01

... during periods of startup, shutdown, and malfunction? 62.15165 Section 62.15165 Protection of Environment... emission limits during periods of startup, shutdown, and malfunction? (a) The emission limits of this subpart apply at all times except during periods of municipal waste combustion unit startup, shutdown, or...

40 CFR 62.15150 - What happens to the operating requirements during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2014 CFR

2014-07-01

... requirements during periods of startup, shutdown, and malfunction? 62.15150 Section 62.15150 Protection of... § 62.15150 What happens to the operating requirements during periods of startup, shutdown, and... municipal waste combustion unit startup, shutdown, or malfunction. (b) Each startup, shutdown, or...

40 CFR 60.1205 - What happens to the operating requirements during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2013 CFR

2013-07-01

... requirements during periods of startup, shutdown, and malfunction? 60.1205 Section 60.1205 Protection of... requirements during periods of startup, shutdown, and malfunction? (a) The operating requirements of this subpart apply at all times except during periods of municipal waste combustion unit startup, shutdown, or...

40 CFR 60.1695 - What happens to the operating requirements during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2013 CFR

2013-07-01

... requirements during periods of startup, shutdown, and malfunction? 60.1695 Section 60.1695 Protection of... Requirements § 60.1695 What happens to the operating requirements during periods of startup, shutdown, and... municipal waste combustion unit startup, shutdown, or malfunction. (b) Each startup, shutdown, or...

40 CFR 63.9814 - What reports must I submit and when?

Code of Federal Regulations, 2011 CFR

2011-07-01

... beginning and ending dates of the reporting period. (4) If you had a startup, shutdown, or malfunction... (d)(1) and (2) of this section. This includes periods of startup, shutdown, and malfunction. (1) The... section. This includes periods of startup, shutdown, and malfunction. (1) The total operating time of each...

40 CFR 63.9814 - What reports must I submit and when?

Code of Federal Regulations, 2012 CFR

2012-07-01

... beginning and ending dates of the reporting period. (4) If you had a startup, shutdown, or malfunction... (d)(1) and (2) of this section. This includes periods of startup, shutdown, and malfunction. (1) The... section. This includes periods of startup, shutdown, and malfunction. (1) The total operating time of each...

40 CFR 63.9814 - What reports must I submit and when?

Code of Federal Regulations, 2014 CFR

2014-07-01

... beginning and ending dates of the reporting period. (4) If you had a startup, shutdown, or malfunction... (d)(1) and (2) of this section. This includes periods of startup, shutdown, and malfunction. (1) The... section. This includes periods of startup, shutdown, and malfunction. (1) The total operating time of each...

40 CFR 63.9814 - What reports must I submit and when?

Code of Federal Regulations, 2013 CFR

2013-07-01

... beginning and ending dates of the reporting period. (4) If you had a startup, shutdown, or malfunction... (d)(1) and (2) of this section. This includes periods of startup, shutdown, and malfunction. (1) The... section. This includes periods of startup, shutdown, and malfunction. (1) The total operating time of each...

Unique structural features of the AIPL1–FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness

PubMed Central

Yadav, Ravi P.; Gakhar, Lokesh; Yu, Liping

2017-01-01

FKBP-domain proteins (FKBPs) are pivotal modulators of cellular signaling, protein folding, and gene transcription. Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) is a distinctive member of the FKBP superfamily in terms of its biochemical properties, and it plays an important biological role as a chaperone of phosphodiesterase 6 (PDE6), an effector enzyme of the visual transduction cascade. Malfunction of mutant AIPL1 proteins triggers a severe form of Leber congenital amaurosis and leads to blindness. The mechanism underlying the chaperone activity of AIPL1 is largely unknown, but involves the binding of isoprenyl groups on PDE6 to the FKBP domain of AIPL1. We solved the crystal structures of the AIPL1–FKBP domain and its pathogenic mutant V71F, both in the apo form and in complex with isoprenyl moieties. These structures reveal a module for lipid binding that is unparalleled within the FKBP superfamily. The prenyl binding is enabled by a unique “loop-out” conformation of the β4-α1 loop and a conformational “flip-out” switch of the key W72 residue. A second major conformation of apo AIPL1–FKBP was identified by NMR studies. This conformation, wherein W72 flips into the ligand-binding pocket and renders the protein incapable of prenyl binding, is supported by molecular dynamics simulations and appears to underlie the pathogenicity of the V71F mutant. Our findings offer critical insights into the mechanisms that underlie AIPL1 function in health and disease, and highlight the structural and functional diversity of the FKBPs. PMID:28739921

Process management using component thermal-hydraulic function classes

DOEpatents

Morman, James A.; Wei, Thomas Y. C.; Reifman, Jaques

1999-01-01

A process management expert system where following malfunctioning of a component, such as a pump, for determining system realignment procedures such as for by-passing the malfunctioning component with on-line speeds to maintain operation of the process at full or partial capacity or to provide safe shut down of the system while isolating the malfunctioning component. The expert system uses thermal-hydraulic function classes at the component level for analyzing unanticipated as well as anticipated component malfunctions to provide recommended sequences of operator actions. Each component is classified according to its thermal-hydraulic function, and the generic and component-specific characteristics for that function. Using the diagnosis of the malfunctioning component and its thermal hydraulic class, the expert system analysis is carried out using generic thermal-hydraulic first principles. One aspect of the invention employs a qualitative physics-based forward search directed primarily downstream from the malfunctioning component in combination with a subsequent backward search directed primarily upstream from the serviced component. Generic classes of components are defined in the knowledge base according to the three thermal-hydraulic functions of mass, momentum and energy transfer and are used to determine possible realignment of component configurations in response to thermal-hydraulic function imbalance caused by the malfunctioning component. Each realignment to a new configuration produces the accompanying sequence of recommended operator actions. All possible new configurations are examined and a prioritized list of acceptable solutions is produced.

Process management using component thermal-hydraulic function classes

DOEpatents

Morman, J.A.; Wei, T.Y.C.; Reifman, J.

1999-07-27

A process management expert system where following malfunctioning of a component, such as a pump, for determining system realignment procedures such as for by-passing the malfunctioning component with on-line speeds to maintain operation of the process at full or partial capacity or to provide safe shut down of the system while isolating the malfunctioning component. The expert system uses thermal-hydraulic function classes at the component level for analyzing unanticipated as well as anticipated component malfunctions to provide recommended sequences of operator actions. Each component is classified according to its thermal-hydraulic function, and the generic and component-specific characteristics for that function. Using the diagnosis of the malfunctioning component and its thermal hydraulic class, the expert system analysis is carried out using generic thermal-hydraulic first principles. One aspect of the invention employs a qualitative physics-based forward search directed primarily downstream from the malfunctioning component in combination with a subsequent backward search directed primarily upstream from the serviced component. Generic classes of components are defined in the knowledge base according to the three thermal-hydraulic functions of mass, momentum and energy transfer and are used to determine possible realignment of component configurations in response to thermal-hydraulic function imbalance caused by the malfunctioning component. Each realignment to a new configuration produces the accompanying sequence of recommended operator actions. All possible new configurations are examined and a prioritized list of acceptable solutions is produced. 5 figs.

40 CFR 63.11226 - How can I assert an affirmative defense if I exceed an emission limit during a malfunction?

Code of Federal Regulations, 2011 CFR

2011-07-01

... you may assert an affirmative defense to a claim for civil penalties for exceedances of numerical... malfunction event at issue. The analysis shall also specify, using best monitoring methods and engineering... avail itself of an affirmative defense to civil penalties for that malfunction. The owner or operator...

40 CFR Table 1 to Subpart Aaaa of... - Applicability of NESHAP General Provisions to Subpart AAAA

Code of Federal Regulations, 2010 CFR

2010-07-01

... reconstructed sources 63.6(e) Operation and maintenance requirements, startup, shutdown and malfunction plan...(b)(2)(i)-(b)(2)(v) General recordkeeping requirements 63.10(d)(5) If actions taken during a startup, shutdown and malfunction plan are consistent with the procedures in the startup, shutdown and malfunction...

40 CFR 63.7835 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2010 CFR

2010-07-01

... that applies to you. This includes periods of startup, shutdown, and malfunction. You also must report...) Startups, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup, shutdown, or malfunction are not violations if you demonstrate to the...

40 CFR 63.7835 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2012 CFR

2012-07-01

... that applies to you. This includes periods of startup, shutdown, and malfunction. You also must report...) Startups, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup, shutdown, or malfunction are not violations if you demonstrate to the...

40 CFR 63.7835 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2013 CFR

2013-07-01

... that applies to you. This includes periods of startup, shutdown, and malfunction. You also must report...) Startups, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup, shutdown, or malfunction are not violations if you demonstrate to the...

40 CFR Table 1 to Subpart Aaaa of... - Applicability of NESHAP General Provisions to Subpart AAAA

Code of Federal Regulations, 2011 CFR

2011-07-01

... reconstructed sources 63.6(e) Operation and maintenance requirements, startup, shutdown and malfunction plan...(b)(2)(i)-(b)(2)(v) General recordkeeping requirements 63.10(d)(5) If actions taken during a startup, shutdown and malfunction plan are consistent with the procedures in the startup, shutdown and malfunction...

40 CFR 63.7835 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2014 CFR

2014-07-01

... that applies to you. This includes periods of startup, shutdown, and malfunction. You also must report...) Startups, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup, shutdown, or malfunction are not violations if you demonstrate to the...

40 CFR 63.7835 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2011 CFR

2011-07-01

... that applies to you. This includes periods of startup, shutdown, and malfunction. You also must report...) Startups, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup, shutdown, or malfunction are not violations if you demonstrate to the...

Dreams In Jungian Psychology: The use of Dreams as an Instrument For Research, Diagnosis and Treatment of Social Phobia.

PubMed

Khodarahimi, Siamak

2009-10-01

The significance of dreams has been explained in psychoanalysis, depth psychology and gestalt therapy. There are many guidelines in analytic psychology for dream interpretation and integration in clinical practice. The present study, based on the Jungian analytic model, incorporated dreams as an instrument for assessment of aetiology, the psychotherapy process and the outcome of treatment for social phobia within a clinical case study. This case study describes the use of dream analysis in treating a female youth with social phobia. The present findings supported the three stage paradigm efficiency in the Jungian model for dream working within a clinical setting, i.e. written details, reassembly with amplification and assimilation. It was indicated that childhood and infantile traumatic events, psychosexual development malfunctions, and inefficient coping skills for solving current life events were expressed in the patient's dreams. Dreams can reflect a patient's aetiology, needs, illness prognosis and psychotherapy outcome. Dreams are an instrument for the diagnosis, research and treatment of mental disturbances in a clinical setting.

Dreams In Jungian Psychology: The use of Dreams as an Instrument For Research, Diagnosis and Treatment of Social Phobia

PubMed Central

Khodarahimi, Siamak

2009-01-01

Background: The significance of dreams has been explained in psychoanalysis, depth psychology and gestalt therapy. There are many guidelines in analytic psychology for dream interpretation and integration in clinical practice. The present study, based on the Jungian analytic model, incorporated dreams as an instrument for assessment of aetiology, the psychotherapy process and the outcome of treatment for social phobia within a clinical case study. Method: This case study describes the use of dream analysis in treating a female youth with social phobia. Results: The present findings supported the three stage paradigm efficiency in the Jungian model for dream working within a clinical setting, i.e. written details, reassembly with amplification and assimilation. It was indicated that childhood and infantile traumatic events, psychosexual development malfunctions, and inefficient coping skills for solving current life events were expressed in the patient’s dreams. Conclusion: Dreams can reflect a patient’s aetiology, needs, illness prognosis and psychotherapy outcome. Dreams are an instrument for the diagnosis, research and treatment of mental disturbances in a clinical setting. PMID:22135511

Anesthesia equipment malfunction: origins and clinical recognition.

PubMed Central

McIntyre, J. W.

1979-01-01

Equipment malfunction is a problem of particular importance during anesthesia and resuscitation. A review of published reports shows that the most common clinical events involve endotracheal tubes, the inspired oxygen concentration, the volume of inspired anesthetic vapours and gases, and pressures in the breathing or ventilation system. It is concluded that protection of a patient from equipment malfunction depends on: (a) appropriate application of standards set by a national standards association; (b) careful evaluation of equipment prior to purchase; (c) comprehension of equipment function by the user; (d) conscientious routine servicing of all systems concerned with anesthesia and resuscitation, and checking after service and before clinical use; (e) preanesthesia testing of equipment, including the use of an oxygen analyser in the breathing circuit; (f) early inclusion of equipment malfunction in the differential diagnosis of events during anesthesia; and (g) rapid action that cannot present a new hazard to the patient to correct the results of apparatus malfunction. PMID:436069

High throughput screening technologies for ion channels

PubMed Central

Yu, Hai-bo; Li, Min; Wang, Wei-ping; Wang, Xiao-liang

2016-01-01

Ion channels are involved in a variety of fundamental physiological processes, and their malfunction causes numerous human diseases. Therefore, ion channels represent a class of attractive drug targets and a class of important off-targets for in vitro pharmacological profiling. In the past decades, the rapid progress in developing functional assays and instrumentation has enabled high throughput screening (HTS) campaigns on an expanding list of channel types. Chronologically, HTS methods for ion channels include the ligand binding assay, flux-based assay, fluorescence-based assay, and automated electrophysiological assay. In this review we summarize the current HTS technologies for different ion channel classes and their applications. PMID:26657056

75 FR 16022 - Airworthiness Directives; Turbomeca S.A. MAKILA 1A and 1A1 Turboshaft Engines

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-31

... investigation by Turbom[eacute]ca are that these malfunctions are due to a lapse of quality control in the... Turbomeca are that these malfunctions are due to a lapse of quality control in the varnishing process... these malfunctions are due to a lapse of quality control in the varnishing process applied to the boards...

40 CFR 63.9925 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2010 CFR

2010-07-01

... includes periods of startup, shutdown, and malfunction. You must also report each instance in which you did... § 63.9931. (b) Startups, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup, shutdown, or malfunction are not violations if you...

40 CFR 63.9925 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2013 CFR

2013-07-01

... includes periods of startup, shutdown, and malfunction. You must also report each instance in which you did... § 63.9931. (b) Startups, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup, shutdown, or malfunction are not violations if you...

40 CFR 63.9925 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2012 CFR

2012-07-01

... includes periods of startup, shutdown, and malfunction. You must also report each instance in which you did... § 63.9931. (b) Startups, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup, shutdown, or malfunction are not violations if you...

40 CFR 63.9925 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2011 CFR

2011-07-01

... includes periods of startup, shutdown, and malfunction. You must also report each instance in which you did... § 63.9931. (b) Startups, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup, shutdown, or malfunction are not violations if you...

40 CFR 63.9925 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2014 CFR

2014-07-01

... includes periods of startup, shutdown, and malfunction. You must also report each instance in which you did... § 63.9931. (b) Startups, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup, shutdown, or malfunction are not violations if you...

40 CFR 63.7501 - How can I assert an affirmative defense if I exceed an emission limitations during a malfunction?

Code of Federal Regulations, 2011 CFR

2011-07-01

... operating limits set forth in § 63.7500 you may assert an affirmative defense to a claim for civil penalties... monitoring methods and engineering judgment, the amount of excess emissions that were the result of the... malfunction, if it wishes to avail itself of an affirmative defense to civil penalties for that malfunction...

40 CFR 63.7501 - How can I assert an affirmative defense if I exceed an emission limitations during a malfunction?

Code of Federal Regulations, 2012 CFR

2012-07-01

... operating limits set forth in § 63.7500 you may assert an affirmative defense to a claim for civil penalties... monitoring methods and engineering judgment, the amount of excess emissions that were the result of the... malfunction, if it wishes to avail itself of an affirmative defense to civil penalties for that malfunction...

40 CFR Table 6 to Subpart Cccc of... - Applicability of General Provisions to Subpart CCCC

Code of Federal Regulations, 2013 CFR

2013-07-01

... Requirements 1. For § 63.6(e) and (f), requirements for startup, shutdown, and malfunctions apply only to.... 3. For § 63.8(c)(1), requirements for startup, shutdown, and malfunctions apply only to malfunctions, and no report pursuant to § 63.10(d)(5)(i) is required. 4. For § 63.8(d), requirements for startup...

40 CFR Table 6 to Subpart Cccc of... - Applicability of General Provisions to Subpart CCCC

Code of Federal Regulations, 2011 CFR

2011-07-01

... Requirements 1. For § 63.6(e) and (f), requirements for startup, shutdown, and malfunctions apply only to.... 3. For § 63.8(c)(1), requirements for startup, shutdown, and malfunctions apply only to malfunctions, and no report pursuant to § 63.10(d)(5)(i) is required. 4. For § 63.8(d), requirements for startup...

40 CFR Table 6 to Subpart Cccc of... - Applicability of General Provisions to Subpart CCCC

Code of Federal Regulations, 2014 CFR

2014-07-01

... Requirements 1. For § 63.6(e) and (f), requirements for startup, shutdown, and malfunctions apply only to.... 3. For § 63.8(c)(1), requirements for startup, shutdown, and malfunctions apply only to malfunctions, and no report pursuant to § 63.10(d)(5)(i) is required. 4. For § 63.8(d), requirements for startup...

40 CFR Table 6 to Subpart Cccc of... - Applicability of General Provisions to Subpart CCCC

Code of Federal Regulations, 2012 CFR

2012-07-01

... Requirements 1. For § 63.6(e) and (f), requirements for startup, shutdown, and malfunctions apply only to.... 3. For § 63.8(c)(1), requirements for startup, shutdown, and malfunctions apply only to malfunctions, and no report pursuant to § 63.10(d)(5)(i) is required. 4. For § 63.8(d), requirements for startup...

40 CFR Table 6 to Subpart Cccc of... - Applicability of General Provisions to Subpart CCCC

Code of Federal Regulations, 2010 CFR

2010-07-01

... Requirements 1. For § 63.6(e) and (f), requirements for startup, shutdown, and malfunctions apply only to.... 3. For § 63.8(c)(1), requirements for startup, shutdown, and malfunctions apply only to malfunctions, and no report pursuant to § 63.10(d)(5)(i) is required. 4. For § 63.8(d), requirements for startup...

Association of Genetic Polymorphisms of Renin–Angiotensin–Aldosterone System-Related Genes with Arterio-Venous Fistula Malfunction in Hemodialysis Patients

PubMed Central

Chen, Yu-Wei; Wu, Yu-Te; Lin, Jhin-Shyaun; Yang, Wu-Chang; Hsu, Yung-Ho; Lee, Kuo-Hua; Ou, Shou-Ming; Chen, Yung-Tai; Shih, Chia-Jen; Lee, Pui-Ching; Chan, Chia-Hao; Chung, Ming-Yi; Lin, Chih-Ching

2016-01-01

Hemodialysis (HD) is the most commonly-used renal replacement therapy for patients with end-stage renal disease worldwide. Arterio-venous fistula (AVF) is the vascular access of choice for HD patients with lowest risk of infection and thrombosis. In addition to environmental factors, genetic factors may also contribute to malfunction of AVF. Previous studies have demonstrated the effect of genotype polymorphisms of angiotensin converting enzyme on vascular access malfunction. We conducted a multicenter, cross-sectional study to evaluate the association between genetic polymorphisms of renin-angiotensin-aldosterone system and AVF malfunction. Totally, 577 patients were enrolled. Their mean age was 60 years old and 53% were male. HD patients with AVF malfunction had longer duration of HD (92.5 ± 68.1 vs. 61.2 ± 51.9 months, p < 0.001), lower prevalence of hypertension (44.8% vs. 55.3%, p = 0.025), right-sided (31.8% vs. 18.4%, p = 0.002) and upper arm AVF (26.6% vs. 9.7%, p < 0.001), and higher mean dynamic venous pressure (DVP) (147.8 ± 28.3 vs. 139.8 ± 30.0, p = 0.021). In subgroup analysis of different genders, location of AVF and DVP remained significant clinical risk factors of AVF malfunction in univariate and multivariate binary logistic regression in female HD patients. Among male HD patients, univariate binary logistic regression analysis revealed that right-side AVF and upper arm location are two important clinical risk factors. In addition, two single nucleotide polymorphisms (SNPs), rs275653 (Odds ratio 1.90, p = 0.038) and rs1492099 (Odds ratio 2.29, p = 0.017) of angiotensin II receptor 1 (AGTR1), were associated with increased risk of AVF malfunction. After adjustment for age and other clinical factors, minor allele-containing genotype polymorphisms (AA and CA) of rs1492099 still remained to be a significant risk factor of AVF malfunction (Odds ratio 3.63, p = 0.005). In conclusion, we demonstrated that rs1492099, a SNP of AGTR1 gene, could be a potential genetic risk factor of AVF malfunction in male HD patients. PMID:27240348

Combined expert system/neural networks method for process fault diagnosis

DOEpatents

Reifman, Jaques; Wei, Thomas Y. C.

1995-01-01

A two-level hierarchical approach for process fault diagnosis is an operating system employs a function-oriented approach at a first level and a component characteristic-oriented approach at a second level, where the decision-making procedure is structured in order of decreasing intelligence with increasing precision. At the first level, the diagnostic method is general and has knowledge of the overall process including a wide variety of plant transients and the functional behavior of the process components. An expert system classifies malfunctions by function to narrow the diagnostic focus to a particular set of possible faulty components that could be responsible for the detected functional misbehavior of the operating system. At the second level, the diagnostic method limits its scope to component malfunctions, using more detailed knowledge of component characteristics. Trained artificial neural networks are used to further narrow the diagnosis and to uniquely identify the faulty component by classifying the abnormal condition data as a failure of one of the hypothesized components through component characteristics. Once an anomaly is detected, the hierarchical structure is used to successively narrow the diagnostic focus from a function misbehavior, i.e., a function oriented approach, until the fault can be determined, i.e., a component characteristic-oriented approach.

Combined expert system/neural networks method for process fault diagnosis

DOEpatents

Reifman, J.; Wei, T.Y.C.

1995-08-15

A two-level hierarchical approach for process fault diagnosis of an operating system employs a function-oriented approach at a first level and a component characteristic-oriented approach at a second level, where the decision-making procedure is structured in order of decreasing intelligence with increasing precision. At the first level, the diagnostic method is general and has knowledge of the overall process including a wide variety of plant transients and the functional behavior of the process components. An expert system classifies malfunctions by function to narrow the diagnostic focus to a particular set of possible faulty components that could be responsible for the detected functional misbehavior of the operating system. At the second level, the diagnostic method limits its scope to component malfunctions, using more detailed knowledge of component characteristics. Trained artificial neural networks are used to further narrow the diagnosis and to uniquely identify the faulty component by classifying the abnormal condition data as a failure of one of the hypothesized components through component characteristics. Once an anomaly is detected, the hierarchical structure is used to successively narrow the diagnostic focus from a function misbehavior, i.e., a function oriented approach, until the fault can be determined, i.e., a component characteristic-oriented approach. 9 figs.

A hemizygous GYG2 mutation and Leigh syndrome: a possible link?

PubMed

Imagawa, Eri; Osaka, Hitoshi; Yamashita, Akio; Shiina, Masaaki; Takahashi, Eihiko; Sugie, Hideo; Nakashima, Mitsuko; Tsurusaki, Yoshinori; Saitsu, Hirotomo; Ogata, Kazuhiro; Matsumoto, Naomichi; Miyake, Noriko

2014-02-01

Leigh syndrome (LS) is an early-onset progressive neurodegenerative disorder characterized by unique, bilateral neuropathological findings in brainstem, basal ganglia, cerebellum and spinal cord. LS is genetically heterogeneous, with the majority of the causative genes affecting mitochondrial malfunction, and many cases still remain unsolved. Here, we report male sibs affected with LS showing ketonemia, but no marked elevation of lactate and pyruvate. To identify their genetic cause, we performed whole exome sequencing. Candidate variants were narrowed down based on autosomal recessive and X-linked recessive models. Only one hemizygous missense mutation (c.665G>C, p.W222S) in glycogenin-2 (GYG2) (isoform a: NM_001079855) in both affected sibs and a heterozygous change in their mother were identified, being consistent with the X-linked recessive trait. GYG2 encodes glycogenin-2 (GYG2) protein, which plays an important role in the initiation of glycogen synthesis. Based on the structural modeling, the mutation can destabilize the structure and result in protein malfunctioning. Furthermore, in vitro experiments showed mutant GYG2 was unable to undergo the self-glucosylation, which is observed in wild-type GYG2. This is the first report of GYG2 mutation in human, implying a possible link between GYG2 abnormality and LS.

Hearing aid malfunction detection system

NASA Technical Reports Server (NTRS)

Kessinger, R. L. (Inventor)

1977-01-01

A malfunction detection system for detecting malfunctions in electrical signal processing circuits is disclosed. Malfunctions of a hearing aid in the form of frequency distortion and/or inadequate amplification by the hearing aid amplifier, as well as weakening of the hearing aid power supply are detectable. A test signal is generated and a timed switching circuit periodically applies the test signal to the input of the hearing aid amplifier in place of the input signal from the microphone. The resulting amplifier output is compared with the input test signal used as a reference signal. The hearing aid battery voltage is also periodically compared to a reference voltage. Deviations from the references beyond preset limits cause a warning system to operate.

Frequency of pacemaker malfunction associated with monopolar electrosurgery during pulse generator replacement or upgrade surgery.

PubMed

Lin, Yun; Melby, Daniel P; Krishnan, Balaji; Adabag, Selcuk; Tholakanahalli, Venkatakrishna; Li, Jian-Ming

2017-08-01

The aim of this study is to investigate the frequency of electrosurgery-related pacemaker malfunction. A retrospective study was conducted to investigate electrosurgery-related pacemaker malfunction in consecutive patients undergoing pulse generator (PG) replacement or upgrade from two large hospitals in Minneapolis, MN between January 2011 and January 2014. The occurrence of this pacemaker malfunction was then studied by using MAUDE database for all four major device vendors. A total of 1398 consecutive patients from 2 large tertiary referral centers in Minneapolis, MN undergoing PG replacement or upgrade surgery were retrospectively studied. Four patients (0.3% of all patients), all with pacemakers from St Jude Medical (2.8%, 4 of 142) had output failure or inappropriately low pacing rate below 30 bpm during electrosurgery, despite being programmed in an asynchronous mode. During the same period, 1174 cases of pacemaker malfunctions were reported on the same models in MAUDE database, 37 of which (3.2%) were electrosurgery-related. Twenty-four cases (65%) had output failure or inappropriate low pacing rate. The distribution of adverse events was loss of pacing (59.5%), reversion to backup pacing (32.4%), inappropriate low pacing rate (5.4%), and ventricular fibrillation (2.7%). The majority of these (78.5%) occurred during PG replacement at ERI or upgrade surgery. No electrosurgery-related malfunction was found in MAUDE database on 862 pacemaker malfunction cases during the same period from other vendors. Electrosurgery during PG replacement or upgrade surgery can trigger output failure or inappropriate low pacing rate in certain models of modern pacemakers. Cautions should be taken for pacemaker-dependent patients.

Temperature control system for optical elements in astronomical instrumentation

NASA Astrophysics Data System (ADS)

Verducci, Orlando; de Oliveira, Antonio C.; Ribeiro, Flávio F.; Vital de Arruda, Márcio; Gneiding, Clemens D.; Fraga, Luciano

2014-07-01

Extremely low temperatures may damage the optical components assembled inside of an astronomical instrument due to the crack in the resin or glue used to attach lenses and mirrors. The environment, very cold and dry, in most of the astronomical observatories contributes to this problem. This paper describes the solution implemented at SOAR for remotely monitoring and controlling temperatures inside of a spectrograph, in order to prevent a possible damage of the optical parts. The system automatically switches on and off some heat dissipation elements, located near the optics, as the measured temperature reaches a trigger value. This value is set to a temperature at which the instrument is not operational to prevent malfunction and only to protect the optics. The software was developed with LabVIEWTM and based on an object-oriented design that offers flexibility and ease of maintenance. As result, the system is able to keep the internal temperature of the instrument above a chosen limit, except perhaps during the response time, due to inertia of the temperature. This inertia can be controlled and even avoided by choosing the correct amount of heat dissipation and location of the thermal elements. A log file records the measured temperature values by the system for operation analysis.

Computer study of emergency shutdowns of a 60-kilowatt reactor Brayton space power system

NASA Technical Reports Server (NTRS)

Tew, R. C.; Jefferies, K. S.

1974-01-01

A digital computer study of emergency shutdowns of a 60-kWe reactor Brayton power system was conducted. Malfunctions considered were (1) loss of reactor coolant flow, (2) loss of Brayton system gas flow, (3)turbine overspeed, and (4) a reactivity insertion error. Loss of reactor coolant flow was the most serious malfunction for the reactor. Methods for moderating the reactor transients due to this malfunction are considered.

Preliminary design study of a regenerative life support system information management and display system

NASA Technical Reports Server (NTRS)

Parker, C. D.; Tommerdahl, J. B.

1972-01-01

The instrumentation requirements for a regenerative life support systems were studied to provide the earliest possible indication of a malfunction that will permit degradation of the environment. Four categories of parameters were investigated: environmental parameters that directly and immediately influence the health and safety of the cabin crew; subsystems' inputs to the cabin that directly maintain the cabin environmental parameters; indications for maintenance or repair; and parameters useful as diagnostic indicators. A data averager concept is introduced which provides a moving average of parameter values that is not influenced by spurious changes, and is convenient for detecting parameter rates of change. A system is included to provide alarms at preselected parameter levels.

Book Analysis: Challenger: A Major Malfunction.

DTIC Science & Technology

1988-04-01

REPORT NUMBER 88-113S TITLE BOOK ANALYSIS: CHALLENGER : A MAJOR MALFUNCTION AUTHOR(S) MAJOR THOMAS M. HALL, USAF FACULTY ADVISOR LT COL JOhN R. GRELLMAN... CHALLENGER : A MAJOR MALFUNCTION 12. PERSONAL AUTHOR(S) Hall, Thomas M., Major, USAF 13a. TYPE OF REPORT 13b. TIME COVERED 14. DATE OF REPORT (Year, Month...identify by block number) FIELD GROUP SUB-GROUP 19. ABSTRACT Continue on reverse if necessary and identify by block number) This report analyzes Challenger

Safety status system for operating room devices.

PubMed

Guédon, Annetje C P; Wauben, Linda S G L; Overvelde, Marlies; Blok, Joleen H; van der Elst, Maarten; Dankelman, Jenny; van den Dobbelsteen, John J

2014-01-01

Since the increase of the number of technological aids in the operating room (OR), equipment-related incidents have come to be a common kind of adverse events. This underlines the importance of adequate equipment management to improve the safety in the OR. A system was developed to monitor the safety status (periodic maintenance and registered malfunctions) of OR devices and to facilitate the notification of malfunctions. The objective was to assess whether the system is suitable for use in an busy OR setting and to analyse its effect on the notification of malfunctions. The system checks automatically the safety status of OR devices through constant communication with the technical facility management system, informs the OR staff real-time and facilitates notification of malfunctions. The system was tested for a pilot period of six months in four ORs of a Dutch teaching hospital and 17 users were interviewed on the usability of the system. The users provided positive feedback on the usability. For 86.6% of total time, the localisation of OR devices was accurate. 62 malfunctions of OR devices were reported, an increase of 12 notifications compared to the previous year. The safety status system was suitable for an OR complex, both from a usability and technical point of view, and an increase of reported malfunctions was observed. The system eases monitoring the safety status of equipment and is a promising tool to improve the safety related to OR devices.

Data presentation techniques for rotating machinery malfunction diagnosis

NASA Technical Reports Server (NTRS)

Spettel, T.

1985-01-01

Baseline steady state data is excellent for documentation of vibration signals at normal operating conditions. Assuming that a set of initial data was acquired with the machinery in a good state of repair, any future changes or deterioration in mechanical condition can be easily compared to the baseline information. Often this type of comparison will yield sufficient information for evaluation of the problem. However, many malfunctions require the analysis of transient data in order to identify the malfunction. Steady-state data formats consist of: Time Base Waveform, Orbit, Spectrum. Transient data formats consist of: Polar, Bode, Cascade. Our objective is to demonstrate the use of the above formats to diagnose a machine malfunction. A turbine-driven compressor train is chosen as an example. The machine train outline drawing is shown.

Discovery and mechanistic study of a class of protein arginine methylation inhibitors.

PubMed

Feng, You; Li, Mingyong; Wang, Binghe; Zheng, Yujun George

2010-08-26

Protein arginine methylation regulates multiple biological processes such as chromatin remodeling and RNA splicing. Malfunction of protein arginine methyltransferases (PRMTs) is correlated with many human diseases. Thus, small molecule inhibitors of protein arginine methylation are of great potential for therapeutic development. Herein, we report a type of compound that blocks PRMT1-mediated arginine methylation at micromolar potency through a unique mechanism. Most of the discovered compounds bear naphthalene and sulfonate groups and are structurally different from typical PRMT substrates, for example, histone H4 and glycine- and arginine-rich sequences. To elucidate the molecular basis of inhibition, we conducted a variety of kinetic and biophysical assays. The combined data reveal that this type of naphthyl-sulfo (NS) molecule directly targets the substrates but not PRMTs for the observed inhibition. We also found that suramin effectively inhibited PRMT1 activity. These findings about novel PRMT inhibitors and their unique inhibition mechanism provide a new way for chemical regulation of protein arginine methylation.

Startup, Shutdown, & Malfunction (SSM) Emissions

EPA Pesticide Factsheets

EPA issued a final action to ensure states have plans in place that are fully consistent with the Clean Air Act and recent court decisions concerning startup, shutdown and malfunction (SSM) operations.

Malfunctions of robotic system in surgery: role and responsibility of surgeon in legal point of view.

PubMed

Ferrarese, Alessia; Pozzi, Giada; Borghi, Felice; Marano, Alessandra; Delbon, Paola; Amato, Bruno; Santangelo, Michele; Buccelli, Claudio; Niola, Massimo; Martino, Valter; Capasso, Emanuele

2016-01-01

Robotic surgery (RS) technology has undergone rapid growth in the surgical field since its approval. In clinical practice, failure of robotic procedures mainly results from a surgeon's inability or to a device malfunction. We reviewed the literature to estimate the impact of this second circumstance in RS and its consequent legal implications. According to data from the literature, device malfunction is rare. We believe it is necessary to complement surgical training with a technical understanding of RS devices.

The research of the malfunction diagnosis and predictions system in the smart electric grid

NASA Astrophysics Data System (ADS)

Wang, Yaqing; Zhang, Guoxing; Xu, Hongbing

2017-03-01

The Chinese smart electric grid constriction has been increasing with the technology development. However, the monitoring equipment and background system which should play important roles did not work as intended and restrict to the efficacy of the smart grid. In this essay, it has researched an intelligentized malfunction diagnosis and predictions system which could work with the existed monitoring equipment to function as whole energy monitoring, common malfunction diagnosis, faulted proactive judgment and automatically elimination.

Design and Testing of a Controller for the Martian Atmosphere Pressure and Humidity Instrument DREAMS-P/H

NASA Astrophysics Data System (ADS)

Tapani Nikkanen, Timo; Schmidt, Walter; Genzer, Maria; Harri, Ari-Matti; Haukka, Harri

2013-04-01

The European Space Agency (ESA), driven by the goal of performing a soft landing on Mars, is planning to launch the Entry, descent and landing Demonstrator Module (EDM)[1] simultaneously with the Trace Gas Orbiter (TGO) as a part of the ExoMars program towards Mars in 2016. As a secondary objective, the EDM will gather meteorological data and observe the electrical environment of the landing site with its Dust characterisation, Risk assessment, and Environmental Analyser on the Martian Surface (DREAMS). The Finnish Meteorological Institute (FMI) is participating in the project by designing, building and testing a pressure and a humidity instrument for Mars, named DREAMS-P and DREAMS-H, respectively. The instruments are based on previous FMI designs, including ones flown on board the Huygens, Phoenix and Mars Science Laboratory.[2] Traditionally, the FMI pressure and humidity instruments have been controlled by an FPGA. However, the need to incorporate more autonomy and modifiability into instruments, cut the development time and component costs, stimulated interest to study a Commercial Off-The-Shelf (COTS) Microcontroller Unit (MCU) based instrument design. Thus, in the DREAMS-P/H design, an automotive MCU is used as the instrument controller. The MCU has been qualified for space by tests in and outside FMI. The DREAMS-P/H controller command and data interface utilizes a RS-422 connection to receive telecommands from and to transmit data to the Central Electronics Unit (CEU) of the DREAMS science package. The two pressure transducers of DREAMS-P and one humidity transducer of DREAMS-H are controlled by a single MCU. The MCU controls the power flow for each transducer and performs pulse counting measurements on sensor and reference channels to retrieve scientific data. Pressure and humidity measurements are scheduled and set up according to a configuration table assigned to each transducer. The configuration tables can be modified during the flight. The whole software is entirely interrupt driven, thus the MCU goes into a power saving standby mode whenever possible. Any measurement or other operation can be stopped by simply interrupting the controller with a telecommand. Software and functional tests of the DREAMS-P/H controller are needed to verify the performance of the instrument in nominal conditions and the correct operation and error detection in anomalous conditions. The nominal conditions tests range from simple functional and performance tests, to longer simulations of continued operation and measurements. Continued operation simulations can be implemented by executing accelerated runs of the expected normal measurement cycles. On the contrary, anomalous conditions tests are used to verify that the controller can handle bad telecommands or anomalous operation of the instrument transducers, for example in the case of malfunctioning sensors. Bad telecommand tests are done by feeding illegal parameters or scrambled telecommands to the controller. Malfunctioning sensors can be simulated by modifying the signals coming from the sensors and reference channels. All expected use cases and all imagined unexpected operating circumstances are studied to ensure that the system is robust. This also makes the planned modification of the design for other future missions easier and safer. Reference: [1] ESA ExoMars EDM mission: http://exploration.esa.int/science-e/www/object/index.cfm?fobjectid=47852 [2] FMI Space Projects website: http://space.fmi.fi/index.php?id=23

75 FR 33220 - Extension of Public Comment Period for Proposed Rule on the Approval and Promulgation of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-11

...; Excess Emissions During Startup, Shutdown, Maintenance, and Malfunction Activities AGENCY: Environmental...; Texas; Excess Emissions During Startup, Shutdown, Maintenance, and Malfunction Activities.'' As...

40 CFR 60.2085 - How do I maintain my operator qualification?

Code of Federal Regulations, 2010 CFR

2010-07-01

... Commercial and Industrial Solid Waste Incineration Units for Which Construction Is Commenced After November... maintenance. (d) Responses to malfunctions or conditions that may lead to malfunction. (e) Discussion of...

40 CFR 60.2635 - What are the operator training and qualification requirements?

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Combustion controls and monitoring. (v) Operation of air pollution control equipment and factors affecting... devices. (vii) Actions to correct malfunctions or conditions that may lead to malfunction. (viii) Bottom...

49 CFR 576.8 - Malfunctions covered.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 7 2010-10-01 2010-10-01 false Malfunctions covered. 576.8 Section 576.8 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY... accident or an injury to a person. ...

40 CFR 60.2120 - Affirmative defense for violation of emission standards during malfunction.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Standards of Performance for Commercial and Industrial Solid Waste Incineration Units Emission Limitations... malfunction event at issue. The analysis shall also specify, using best monitoring methods and engineering...

Startup, Shutdown, & Malfunction (SSM) Emissions at Industrial Facilities

EPA Pesticide Factsheets

EPA issued a final action to ensure states have plans in place that are fully consistent with the Clean Air Act and recent court decisions concerning startup, shutdown and malfunction (SSM) operations.

40 CFR 1048.110 - How must my engines diagnose malfunctions?

Code of Federal Regulations, 2011 CFR

2011-07-01

... engine-diagnostic requirements apply for engines equipped with three-way catalysts and closed-loop... malfunction whenever the air-fuel ratio does not cross stoichiometry for one minute of intended closed-loop...

Fluoroscopic guide wire manipulation of malfunctioning peritoneal dialysis catheters initially placed by interventional radiologists.

PubMed

Kwon, Young Ho; Kwon, Se Hwan; Oh, Joo Hyeong; Jeong, Kyung Hwan; Lee, Tae Won

2014-06-01

To assess the efficacy of fluoroscopic guide wire manipulation in patients with malfunctioning peritoneal dialysis (PD) catheters that were initially placed by interventional radiologists under fluoroscopic guidance. From January 2002 to April 2012, 52 patients (mean age, 52.8 y ± 2.10s; range, 12-79 y) with malfunctioning PD catheters in whom fluoroscopic guide wire manipulation was performed were retrospectively reviewed. Technical success, clinical success, and complications were evaluated. Technical success was defined as fluoroscopically verified, successful catheter repositioning and adequate dialysate drainage after the procedure. Clinical success was defined as maintenance of PD catheter function for at least 30 days after the manipulation. During the study period, 72 manipulations (68 initial manipulations and 4 remanipulations) for malfunctioning PD catheters were done. The technical success rate was 74% (50 of 68) for initial manipulations and 75% (3 of 4) for remanipulations. The overall clinical success rate was 47% (32 of 68) for initial manipulations and 0% (0 of 4) for remanipulations. The primary causes of catheter malfunction were extraluminal obstruction by omental wrapping or adhesions in 43 of 68 cases (63.2%) and catheter malposition in 25 of 68 (36.8%) cases. There were no procedure-related major complications. Fluoroscopic guide wire manipulation in patients with malfunctioning PD catheters initially placed by interventional radiologists is a simple procedure, an effective way of prolonging PD catheter life, and a recommended procedure before invasive surgical procedures. Copyright © 2014 SIR. Published by Elsevier Inc. All rights reserved.

40 CFR 63.6105 - What are my general requirements for complying with this subpart?

Code of Federal Regulations, 2011 CFR

2011-07-01

... to you at all times except during startup, shutdown, and malfunctions. (b) If you must comply with... times including during startup, shutdown, and malfunction. Testing and Initial Compliance Requirements ...

40 CFR 1048.110 - How must my engines diagnose malfunctions?

Code of Federal Regulations, 2010 CFR

2010-07-01

..., the MIL may stay off during later engine operation. (d) Store trouble codes in computer memory. Record and store in computer memory any diagnostic trouble codes showing a malfunction that should illuminate...

Post market surveillance in the german medical device sector - current state and future perspectives.

PubMed

Zippel, Claus; Bohnet-Joschko, Sabine

2017-08-01

Medical devices play a central role in the diagnosis and treatment of diseases but also bring the potential for adverse events, hazards or malfunction with serious consequences for patients and users. Medical device manufacturers are therefore required by law to monitor the performance of medical devices that have been approved by the competent authorities (post market surveillance). Conducting a nationwide online-survey in the German medical device sector in Q2/2014 in order to explore the current status of the use of post market instruments we obtained a total of 118 complete data sets, for a return rate of 36%. The survey included manufacturers of different sizes, producing medical devices of all risk classes. The post market instruments most frequently reported covered the fields of production monitoring and quality management as well as literature observation, regulatory vigilance systems, customer knowledge management and market observation while Post Market Clinical Follow-up and health services research were being used less for product monitoring. We found significant differences between the different risk classes of medical devices produced and the intensity of use of post market instruments. Differences between company size and the intensity of instruments used were hardly detected. Results may well contribute to the development of device monitoring which is a crucial element of the policy and regulatory system to identify device-related safety issues. Copyright © 2017 Elsevier B.V. All rights reserved.

40 CFR 63.762 - Affirmative defense for violations of emission standards during malfunction.

Code of Federal Regulations, 2013 CFR

2013-07-01

... an affirmative defense to a claim for civil penalties for violations of such standards that are... malfunction event at issue. The analysis shall also specify, using best monitoring methods and engineering...

40 CFR 63.1272 - Affirmative defense for violations of emission standards during malfunction.

Code of Federal Regulations, 2014 CFR

2014-07-01

... an affirmative defense to a claim for civil penalties for violations of such standards that are... malfunction event at issue. The analysis shall also specify, using best monitoring methods and engineering...

40 CFR 63.762 - Affirmative defense for violations of emission standards during malfunction.

Code of Federal Regulations, 2014 CFR

2014-07-01

... an affirmative defense to a claim for civil penalties for violations of such standards that are... malfunction event at issue. The analysis shall also specify, using best monitoring methods and engineering...

40 CFR 63.1272 - Affirmative defense for violations of emission standards during malfunction.

Code of Federal Regulations, 2013 CFR

2013-07-01

... an affirmative defense to a claim for civil penalties for violations of such standards that are... malfunction event at issue. The analysis shall also specify, using best monitoring methods and engineering...

40 CFR 60.2685 - Affirmative defense for violation of emission standards during malfunction.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model... methods and engineering judgment, the amount of any emissions that were the result of the malfunction. (b...

40 CFR 60.2685 - Affirmative defense for violation of emission standards during malfunction.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model... methods and engineering judgment, the amount of any emissions that were the result of the malfunction. (b...

An optimal diagnostic strategy for finding malfunctioning components in systems

NASA Technical Reports Server (NTRS)

Wong, J. T.

1983-01-01

A solution to the following problem is presented: Given that an n-component functional system is down, it is required to find a malfunctioning component of the system such that the expected expenditure is minimum.

Thermal Test Verification of Emission Control through Directional Baffles for the James Webb Space Telescope

NASA Technical Reports Server (NTRS)

Garrison, Matthew; Rashford, Robert; Switzer, Timothy; Shaw, David; White, Bryant; Lynch, Michael; Huber, Frank; Bachtell, Neal

2009-01-01

The thermal performance of NASA s planned James Webb Space Telescope is highly reliant on a collection of directional baffles that are part of the Integrated Science Instrument Module Electronics Compartment. In order to verify the performance of the baffle concept, two test assemblies were recently fabricated and tested at the Goddard Space Flight Center. The centerpiece of the testing was a fixture that used bolometers to measure the emission field through the baffles while the radiator panels and baffles ran a flight-like temperature. Although not all test goals were able to be met due to facility malfunctions, the test was able to prove the design viability enough to gain approval to begin manufacturing the flight article.

Lunar orbital mass spectrometer experiment

NASA Technical Reports Server (NTRS)

Lord, W. P.

1971-01-01

The design, development, manufacture, test and calibration of five lunar orbital mass spectrometers with the four associated ground support equipment test sets are discussed. A mass spectrometer was installed in the Apollo 15 and one in the Apollo 16 Scientific Instrument Module within the Service Module. The Apollo 15 mass spectrometer was operated with collection of 38 hours of mass spectra data during lunar orbit and 50 hours of data were collected during transearth coast. The Apollo 16 mass spectrometer was operated with collection of 76 hours of mass spectra data during lunar orbit. However, the Apollo 16 mass spectrometer was ejected into lunar orbit upon malfunction of spacecraft boom system just prior to transearth insection and no transearth coast data was possible.

40 CFR 60.286a - Affirmative defense for violations of emission standards during malfunction.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., you may assert an affirmative defense to a claim for civil penalties for violations of such standards... malfunction event at issue. The analysis must also specify, using best monitoring methods and engineering...

40 CFR 63.11226 - How can I assert an affirmative defense if I exceed an emission limit during a malfunction?

Code of Federal Regulations, 2012 CFR

2012-07-01

... Hazardous Air Pollutants for Industrial, Commercial, and Institutional Boilers Area Sources Continuous... malfunction event at issue. The analysis shall also specify, using best monitoring methods and engineering...

40 CFR 63.6105 - What are my general requirements for complying with this subpart?

Code of Federal Regulations, 2014 CFR

2014-07-01

... limitations which apply to you at all times except during startup, shutdown, and malfunctions. (b) If you must... emissions at all times including during startup, shutdown, and malfunction. Testing and Initial Compliance...

40 CFR 63.6105 - What are my general requirements for complying with this subpart?

Code of Federal Regulations, 2012 CFR

2012-07-01

... limitations which apply to you at all times except during startup, shutdown, and malfunctions. (b) If you must... emissions at all times including during startup, shutdown, and malfunction. Testing and Initial Compliance...

40 CFR 63.6105 - What are my general requirements for complying with this subpart?

Code of Federal Regulations, 2013 CFR

2013-07-01

... limitations which apply to you at all times except during startup, shutdown, and malfunctions. (b) If you must... emissions at all times including during startup, shutdown, and malfunction. Testing and Initial Compliance...

75 FR 67634 - Parts and Accessories Necessary for Safe Operation: Antilock Brake Systems

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-03

... trailer with an antilock brake system be equipped with an external malfunction indicator lamp. DATES: This... malfunction indicator lamp. FMCSA used the Agency's direct final rule procedures (75 FR 29915, May 28, 2010...

40 CFR 63.11496 - What are the standards and compliance requirements for process vents?

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Startup, shutdown, malfunction (SSM). Section 63.998(b)(2)(iii),(b)(6)(i)(A), and (d)(3) do not apply for.... (i) Startup, shutdown, and malfunction (SSM). References to SSM provisions in subparts that are...

40 CFR 63.11496 - What are the standards and compliance requirements for process vents?

Code of Federal Regulations, 2012 CFR

2012-07-01

...) Startup, shutdown, malfunction (SSM). Section 63.998(b)(2)(iii),(b)(6)(i)(A), and (d)(3) do not apply for.... (i) Startup, shutdown, and malfunction (SSM). References to SSM provisions in subparts that are...

40 CFR 63.11496 - What are the standards and compliance requirements for process vents?

Code of Federal Regulations, 2011 CFR

2011-07-01

...) Startup, shutdown, malfunction (SSM). Section 63.998(b)(2)(iii),(b)(6)(i)(A), and (d)(3) do not apply for.... (i) Startup, shutdown, and malfunction (SSM). References to SSM provisions in subparts that are...

40 CFR 52.1483 - Malfunction regulations.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Malfunction regulations. 52.1483 Section 52.1483 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... regulations. (a) The following regulations are disapproved because they would permit the exemption of sources...

40 CFR 52.1483 - Malfunction regulations.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Malfunction regulations. 52.1483 Section 52.1483 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... regulations. (a) The following regulations are disapproved because they would permit the exemption of sources...

40 CFR 63.9610 - What are my general requirements for complying with this subpart?

Code of Federal Regulations, 2011 CFR

2011-07-01

... section at all times, except during periods of startup, shutdown, and malfunction. The terms startup... develop a written startup, shutdown, and malfunction plan according to the provisions in § 63.6(e)(3). [68...

M825A1 White Phosphorous Malfunction Investigation Related to the M739/ M739A1 Safing and Arming Module

DTIC Science & Technology

1993-08-01

AD-A269 205 AD AD-E402 378 Technical Report ARAED-TR-92031 M825A1 WHITE PHOSPHOROUS MALFUNCTION INVESTIGATION RELATED TO THE M739 /M739A1 SAFING AND...Aug 1993 - 4. TITLE AND SUBTITLE 5 FUNDING NUMBERS M825A1 WHITE PHOSPHOROUS MALFUNCTION INVESTIGATION RELATED TO THE M739 /M739AI SAFING AND ARMING...LT). An investigation of the data revealed changes in the burster and the M739 /M739A1 safing and arming (S&A) module. The Armaments Research

Malfunction of cardiac devices after radiotherapy without direct exposure to ionizing radiation: mechanisms and experimental data.

PubMed

Zecchin, Massimo; Morea, Gaetano; Severgnini, Mara; Sergi, Elisabetta; Baratto Roldan, Anna; Bianco, Elisabetta; Magnani, Silvia; De Luca, Antonio; Zorzin Fantasia, Anna; Salvatore, Luca; Milan, Vittorino; Giannini, Gianrossano; Sinagra, Gianfranco

2016-02-01

Malfunctions of cardiac implantable electronical devices (CIED) have been described after high-energy radiation therapy even in the absence of direct exposure to ionizing radiation, due to diffusion of neutrons (n) causing soft errors in inner circuits. The purpose of the study was to analyse the effect of scattered radiation on different types and models of CIED and the possible sources of malfunctions. Fifty-nine explanted CIED were placed on an anthropomorphous phantom of tissue-equivalent material, and a high-energy photon (15 MV) radiotherapy course (total dose = 70 Gy) for prostate treatment was performed. All devices were interrogated before and after radiation. Radiation dose, the electromagnetic field, and neutron fluence at the CIED site were measured. Thirty-four pacemakers (PM) and 25 implantable cardioverter-defibrillators (ICD) were analysed. No malfunctions were detected before radiation. After radiation a software malfunction was evident in 13 (52%) ICD and 6 (18%) PM; no significant electromagnetic field or photon radiations were detected in the thoracic region. Neutron capture was demonstrated by the presence of the (198)Au((197)Au + n) or (192)Ir((191)Ir + n) isotope activation; it was significantly greater in ICD than in PM and non-significantly greater in damaged devices. A greater effect in St Jude PM (2/2 damaged), Boston (9/11), and St Jude ICD (3/6) and in older ICD models was observed; the year of production was not relevant in PM. High-energy radiation can cause different malfunctions on CIED, particularly ICD, even without direct exposure to ionizing radiation due to scattered radiation of neutrons produced by the linear accelerator. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2015. For permissions please email: journals.permissions@oup.com.

The role of laparoscopic surgery in the management of a malfunctioning peritoneal catheter.

PubMed

Alabi, A; Dholakia, S; Ablorsu, E

2014-11-01

Peritoneal catheter malfunction is a common complication of peritoneal dialysis (PD). It has a high failure rate with conservative management. Catheter replacement was historically the standard surgical treatment of choice. Nowadays, laparoscopy has been introduced as an alternative surgical modality to rescue the malfunctioning peritoneal catheter and also offers the possibility of replacement if indicated. The aim of this study was to compare the outcomes of these two surgical modalities. The medical records of consecutive patients who underwent surgical treatment for malfunctioning PD catheters (between January 2010 and April 2013) were analysed. The primary outcome included successful return to adequate PD. The secondary endpoint was length of catheter patency and the cause of catheter failure. A total of 32 cases were identified, of which 8 had open catheter replacement and 24 had a laparoscopic intervention. The overall median follow-up duration was 12.5 months. The success rate for laparoscopic surgery in terms of functioning catheter at 12 months was 62.5% but only 37.5% for open surgery. The mean length of catheter patency after laparoscopic intervention was 31.6 months compared with only 13.6 months for the open surgery group. The most common cause of catheter failure diagnosed during laparoscopic intervention was catheter migration (33.0%), followed by omental wrap and catheter blockage by fibrin/blood plug (25.0% each). Open surgery did not have any diagnostic potential. Laparoscopy is the treatment of choice for malfunctioning PD. Its proven benefit includes simultaneous identification of the aetiological cause of malfunction together with direct correction of this problem, thereby maximising outcome. It also allows for rapid recommencement of PD and avoidance of haemodialysis, saving cost and resources.

Diagnostic procedures for catheter malfunction in programmable implantable intraperitoneal insulin infusion devices.

PubMed

Olsen, C L; Turner, D S; Iravani, M; Waxman, K; Selam, J L; Charles, M A

1995-01-01

To evaluate the roles of 1) abdominal radiography, 2) a pressure diagnostic procedure (PDP) using a standardized diluent infusion into the catheter sideport, and 3) radiocontrast imaging of the catheter lumen as procedures for diagnosing catheter malfunction in diabetic patients implanted with a programmable intraperitoneal infusion device. Sixteen type I diabetic patients implanted with Infusaid programmable intraperitoneal insulin pumps were studied. The ability of the above three procedures to assist diagnosis of catheter malfunction and distinguish between occlusion and catheter breakage was retrospectively analyzed. Glycated hemoglobin was measured to determine the clinical importance of catheter malfunctions and decreases in pump flow due to insulin aggregation in the pump chamber. Mean glycated hemoglobin levels increased significantly from 8.0 +/- 0.3 to 9.0 +/- 0.4% (P < 0.05) before and after catheter malfunction, but not during pump flow slowdowns. Mean peak pressure during PDP was 1.96 +/- 0.14 psi (P < 0.01 vs. normal) in reversibly occluded catheters and 1.86 +/- 0.35 psi (P < 0.05 vs. normal) in broken catheters, compared with 1.32 +/- 0.23 psi in normal catheters. Decay times during PDP were > 50 s for both reversibly occluded and broken catheters (P < 0.001 vs. normal of 3.6 +/- 0.82 s). Abdominal radiographs and sideport injections of contrast material were used to distinguish the types of broken catheters. Catheter breakage and occlusion are complications in implantable insulin infusion systems and result in metabolic deterioration. The presence of a sideport allows pressure data and radiographic procedures to assist in determining the cause of catheter malfunction. A diagnostic algorithm was generated to improve efficiency in investigating catheter problems.

Measurements of matric and water potentials in unsaturated tuff at Yucca Mountain, Nevada

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thamir, F.; McBride, C.M.

1985-12-31

Two types of instruments were installed in a borehole in order to monitor matric and water potentials of various hydrogeologic units consisting of tuff. The borehole was drilled as part of a study to provide information to the US Department of Energy for their use in evaluating Yucca Mountain, Nevada, for a repository for high-level radioactive waste. Heat-dissipation probes were used to monitor matric potentials and thermocouple psychrometers were used to monitor water potentials. Two major concerns regarding the use of these instruments in deep boreholes are: (1) the effect of length of the lead wires, and (2) the inabilitymore » to recalibrate the instruments after installation. The length of the lead wire contributes to the source resistance and lead capacitance, which affects the signal settling time. Both instruments tested proved to be insensitive to lead-wire length, except when connected to smaller input-impedance data loggers. Thermocouple wires were more sensitive than heat-dissipation probe wires because of their greater resistance and quality of voltmeters used. Two thermocouple psychrometers were installed at every instrument station for backup and verification of data, because the instruments could not be recalibrated in situ. Multiple scanning rather than single-point scanning of the evaporation curve of a thermocouple psychrometer could give more reliable data, especially in differentiating between very wet and very dry environments. An isolated power supply needs to be used for each heat dissipation probe rather than a single power supply for a group of probes to avoid losing data from all probes when one probe malfunctions. This type of system is particularly desirable if the site is unattended by an operator for as long as a month. 20 refs., 13 figs., 2 tabs.« less

Utility of an airframe referenced spatial auditory display for general aviation operations

NASA Astrophysics Data System (ADS)

Naqvi, M. Hassan; Wigdahl, Alan J.; Ranaudo, Richard J.

2009-05-01

The University of Tennessee Space Institute (UTSI) completed flight testing with an airframe-referenced localized audio cueing display. The purpose was to assess its affect on pilot performance, workload, and situational awareness in two scenarios simulating single-pilot general aviation operations under instrument meteorological conditions. Each scenario consisted of 12 test procedures conducted under simulated instrument meteorological conditions, half with the cue off, and half with the cue on. Simulated aircraft malfunctions were strategically inserted at critical times during each test procedure. Ten pilots participated in the study; half flew a moderate workload scenario consisting of point to point navigation and holding pattern operations and half flew a high workload scenario consisting of non precision approaches and missed approach procedures. Flight data consisted of aircraft and navigation state parameters, NASA Task Load Index (TLX) assessments, and post-flight questionnaires. With localized cues there was slightly better pilot technical performance, a reduction in workload, and a perceived improvement in situational awareness. Results indicate that an airframe-referenced auditory display has utility and pilot acceptance in general aviation operations.

The baric probe: a novel long-term implantable intracranial pressure monitor with ultrasound-based interrogation.

PubMed

Limbrick, David D; Lake, Stephen; Talcott, Michael; Alexander, Benjamin; Wight, Samuel; Willie, Jon T; Richard, William D; Genin, Guy M; Leuthardt, Eric C

2012-12-01

Prompt diagnosis of shunt malfunction is critical in preventing neurological morbidity and death in individuals with hydrocephalus; however, diagnostic methods for this condition remain limited. For several decades, investigators have sought a long-term, implantable intracranial pressure (ICP) monitor to assist in the diagnosis of shunt malfunction, but efforts have been impeded by device complexity, marked measurement drift, and limited instrumentation lifespan. In the current report, the authors introduce an entirely novel, simple, compressible gas design that addresses each of these problems. The device described herein, termed the "baric probe," consists of a subdural fluid bladder and multichannel indicator that monitors the position of an air-fluid interface (AFI). A handheld ultrasound probe is used to interrogate the baric probe in vivo, permitting noninvasive ICP determination. To assess the function of device prototypes, ex vivo experiments were conducted using a water column, and short- and long-term in vivo experiments were performed using a porcine model with concurrent measurements of ICP via a fiberoptic monitor. Following a toe region of approximately 2 cm H(2)O, the baric probe's AFI demonstrated a predictable linear relationship to ICP in both ex vivo and in vivo models. After a 2-week implantation of the device, this linear relationship remained robust and reproducible. Further, changes in ICP were observed with the baric probe, on average, 3 seconds in advance of the fiberoptic ICP monitor reading. The authors demonstrate "proof-of-concept" and feasibility for the baric probe, a long-term implantable ICP monitor designed to facilitate the prompt and accurate diagnosis of shunt malfunction. The baric probe showed a consistent linear relationship between ICP and the device's AFI in ex vivo and short- and long-term in vivo models. With a low per-unit cost, a reduced need for radiography or CT, and an indicator that can be read with a handheld ultrasound probe that interfaces with any smart phone, the baric probe promises to simplify the care of patients with shunt-treated hydrocephalus throughout both the developed and the developing world.

14 CFR 60.25 - Operation with missing, malfunctioning, or inoperative components.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Operation with missing, malfunctioning, or inoperative components. 60.25 Section 60.25 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN FLIGHT SIMULATION TRAINING DEVICE INITIAL AND CONTINUING...

14 CFR 60.25 - Operation with missing, malfunctioning, or inoperative components.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Operation with missing, malfunctioning, or inoperative components. 60.25 Section 60.25 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN FLIGHT SIMULATION TRAINING DEVICE INITIAL AND CONTINUING...

14 CFR 60.25 - Operation with missing, malfunctioning, or inoperative components.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Operation with missing, malfunctioning, or inoperative components. 60.25 Section 60.25 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN FLIGHT SIMULATION TRAINING DEVICE INITIAL AND CONTINUING...

14 CFR 60.25 - Operation with missing, malfunctioning, or inoperative components.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Operation with missing, malfunctioning, or inoperative components. 60.25 Section 60.25 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN FLIGHT SIMULATION TRAINING DEVICE INITIAL AND CONTINUING...

14 CFR 60.25 - Operation with missing, malfunctioning, or inoperative components.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Operation with missing, malfunctioning, or inoperative components. 60.25 Section 60.25 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN FLIGHT SIMULATION TRAINING DEVICE INITIAL AND CONTINUING...

40 CFR 63.1335 - General recordkeeping and reporting provisions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Precompliance Report. The Administrator may deem alternative controls to be equivalent to the controls required... (CONTINUED) National Emission Standards for Hazardous Air Pollutant Emissions: Group IV Polymers and Resins... malfunction and a program for corrective action for malfunctioning process and air pollution control equipment...

40 CFR 63.310 - Requirements for startups, shutdowns, and malfunctions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... plan, the owner or operator may use the standard operating procedures manual for the battery, provided... startup, shutdown, and malfunction plan that describes procedures for operating the battery, including... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE...

40 CFR 63.310 - Requirements for startups, shutdowns, and malfunctions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... plan, the owner or operator may use the standard operating procedures manual for the battery, provided... startup, shutdown, and malfunction plan that describes procedures for operating the battery, including... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE...

40 CFR 63.310 - Requirements for startups, shutdowns, and malfunctions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... plan, the owner or operator may use the standard operating procedures manual for the battery, provided... startup, shutdown, and malfunction plan that describes procedures for operating the battery, including... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE...

40 CFR 63.310 - Requirements for startups, shutdowns, and malfunctions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... plan, the owner or operator may use the standard operating procedures manual for the battery, provided... startup, shutdown, and malfunction plan that describes procedures for operating the battery, including... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE...

76 FR 12743 - Medical Device Reporting; Malfunction Reporting Frequency

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-08

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-N-0097] Medical Device Reporting; Malfunction Reporting Frequency AGENCY: Food and Drug Administration, HHS... compliance with FDA's Medical Device Reporting regulation, pending future FDA notice under the Federal Food...

40 CFR 63.2250 - What are the general requirements?

Code of Federal Regulations, 2012 CFR

2012-07-01

..., except during periods of process unit or control device startup, shutdown, and malfunction; prior to process unit initial startup; and during the routine control device maintenance exemption specified in... practice requirements are not operating, or during periods of startup, shutdown, and malfunction. Startup...

40 CFR 63.2250 - What are the general requirements?

Code of Federal Regulations, 2013 CFR

2013-07-01

..., except during periods of process unit or control device startup, shutdown, and malfunction; prior to process unit initial startup; and during the routine control device maintenance exemption specified in... practice requirements are not operating, or during periods of startup, shutdown, and malfunction. Startup...

40 CFR 63.2250 - What are the general requirements?

Code of Federal Regulations, 2014 CFR

2014-07-01

..., except during periods of process unit or control device startup, shutdown, and malfunction; prior to process unit initial startup; and during the routine control device maintenance exemption specified in... practice requirements are not operating, or during periods of startup, shutdown, and malfunction. Startup...

40 CFR 60.51Da - Reporting requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... excluded from the calculation of average emission rates because of startup, shutdown, malfunction (NOX only... than startup, shutdown, malfunction, or emergency conditions. (6) Identification of “F” factor used for calculations, method of determination, and type of fuel combusted. (7) Identification of times when hourly...

49 CFR 234.103 - Timely response to report of malfunction.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Timely response to report of malfunction. 234.103 Section 234.103 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SAFETY, INCLUDING SIGNAL SYSTEMS, STATE ACTION PLANS...

49 CFR 234.103 - Timely response to report of malfunction.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Timely response to report of malfunction. 234.103 Section 234.103 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SAFETY, INCLUDING SIGNAL SYSTEMS, STATE ACTION PLANS...

40 CFR 62.14610 - How do I maintain my operator qualification?

Code of Federal Regulations, 2013 CFR

2013-07-01

...) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF STATE PLANS FOR DESIGNATED FACILITIES AND POLLUTANTS Federal Plan Requirements for Commercial and Industrial Solid Waste Incineration Units That...) Responses to malfunctions or conditions that may lead to malfunction. (e) Discussion of operating problems...

49 CFR 234.103 - Timely response to report of malfunction.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Timely response to report of malfunction. 234.103 Section 234.103 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SAFETY, INCLUDING SIGNAL SYSTEMS, STATE ACTION PLANS...

Upgrading the Space Shuttle Caution and Warning System

NASA Technical Reports Server (NTRS)

McCandless, Jeffrey W.; McCann, Robert S.; Hilty, Bruce T.

2005-01-01

A report describes the history and the continuing evolution of an avionic system aboard the space shuttle, denoted the caution and warning system, that generates visual and auditory displays to alert astronauts to malfunctions. The report focuses mainly on planned human-factors-oriented upgrades of an alphanumeric fault-summary display generated by the system. Such upgrades are needed because the display often becomes cluttered with extraneous messages that contribute to the difficulty of diagnosing malfunctions. In the first of two planned upgrades, the fault-summary display will be rebuilt with a more logical task-oriented graphical layout and multiple text fields for malfunction messages. In the second upgrade, information displayed will be changed, such that text fields will indicate only the sources (that is, root causes) of malfunctions; messages that are not operationally useful will no longer appear on the displays. These and other aspects of the upgrades are based on extensive collaboration among astronauts, engineers, and human-factors scientists. The report describes the human-factors principles applied in the upgrades.

Cerebrospinal Fluid Lumbar Tapping Utilization for Suspected Ventriculoperitoneal Shunt Under-Drainage Malfunctions.

PubMed

Lee, Jong-Beom; Ahn, Ho-Young; Lee, Hong-Jae; Yang, Ji-Ho; Yi, Jin-Seok; Lee, Il-Woo

2017-01-01

The diagnosis of shunt malfunction can be challenging since neuroimaging results are not always correlated with clinical outcomes. The purpose of this study was to evaluate the efficacy of a simple, minimally invasive cerebrospinal fluid (CSF) lumbar tapping test that predicts shunt under-drainage in hydrocephalus patients. We retrospectively reviewed the clinical and radiological features of 48 patients who underwent routine CSF lumbar tapping after ventriculoperitoneal shunt (VPS) operation using a programmable shunting device. We compared shunt valve opening pressure and CSF lumbar tapping pressure to check under-drainage. The mean pressure difference between valve opening pressure and CSF lumbar tapping pressure of all patients were 2.21±24.57 mmH 2 O. The frequency of CSF lumbar tapping was 2.06±1.26 times. Eighty five times lumbar tapping of 41 patients showed that their VPS function was normal which was consistent with clinical improvement and decreased ventricle size on computed tomography scan. The mean pressure difference in these patients was -3.69±19.20 mmH 2 O. The mean frequency of CSF lumbar tapping was 2.07±1.25 times. Fourteen cases of 10 patients revealed suspected VPS malfunction which were consistent with radiological results and clinical symptoms, defined as changes in ventricle size and no clinical improvement. The mean pressure difference was 38.07±23.58 mmH 2 O. The mean frequency of CSF lumbar tapping was 1.44±1.01 times. Pressure difference greater than 35 mmH 2 O was shown in 2.35% of the normal VPS function group (2 of 85) whereas it was shown in 64.29% of the suspected VPS malfunction group (9 of 14). The difference was statistically significant ( p =0.000001). Among 10 patients with under-drainage, 5 patients underwent shunt revision. The causes of the shunt malfunction included 3 cases of proximal occlusion and 2 cases of distal obstruction and valve malfunction. Under-drainage of CSF should be suspected if CSF lumbar tapping pressure is 35 mmH 2 O higher than the valve opening pressure and shunt malfunction evaluation or adjustment of the valve opening pressure should be made.

40 CFR 63.11890 - What are my additional general requirements for complying with this subpart?

Code of Federal Regulations, 2012 CFR

2012-07-01

... malfunctions and required monitoring system quality assurance or quality control activities (including, as... malfunctions, or required monitoring system quality assurance or control activities in calculations used to... source, including associated air pollution control components and monitoring system components, in a...

40 CFR 1045.110 - How must my engines diagnose malfunctions?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 32 2010-07-01 2010-07-01 false How must my engines diagnose malfunctions? 1045.110 Section 1045.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION MARINE ENGINES AND VESSELS...

40 CFR 1045.110 - How must my engines diagnose malfunctions?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 34 2013-07-01 2013-07-01 false How must my engines diagnose malfunctions? 1045.110 Section 1045.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION MARINE ENGINES AND VESSELS...

40 CFR 1045.110 - How must my engines diagnose malfunctions?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 33 2014-07-01 2014-07-01 false How must my engines diagnose malfunctions? 1045.110 Section 1045.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION MARINE ENGINES AND VESSELS...

40 CFR 1045.110 - How must my engines diagnose malfunctions?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 34 2012-07-01 2012-07-01 false How must my engines diagnose malfunctions? 1045.110 Section 1045.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION MARINE ENGINES AND VESSELS...

40 CFR 1045.110 - How must my engines diagnose malfunctions?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 33 2011-07-01 2011-07-01 false How must my engines diagnose malfunctions? 1045.110 Section 1045.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION MARINE ENGINES AND VESSELS...

40 CFR 63.2862 - What records must I keep?

Code of Federal Regulations, 2012 CFR

2012-07-01

...) initial startup period or the § 63.2850(e)(2) malfunction period. Complete both plans before the... such as normal operation, nonoperating, initial startup period, malfunction period, or exempt operation... inventory. (ii) The operating status of your source such as normal operation, nonoperating, initial startup...

40 CFR 63.2862 - What records must I keep?

Code of Federal Regulations, 2013 CFR

2013-07-01

...) initial startup period or the § 63.2850(e)(2) malfunction period. Complete both plans before the... such as normal operation, nonoperating, initial startup period, malfunction period, or exempt operation... inventory. (ii) The operating status of your source such as normal operation, nonoperating, initial startup...

40 CFR 63.2862 - What records must I keep?

Code of Federal Regulations, 2014 CFR

2014-07-01

...) initial startup period or the § 63.2850(e)(2) malfunction period. Complete both plans before the... such as normal operation, nonoperating, initial startup period, malfunction period, or exempt operation... inventory. (ii) The operating status of your source such as normal operation, nonoperating, initial startup...

40 CFR 63.1164 - Reporting requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... written extension of compliance. (c) Periodic startup, shutdown, and malfunction reports. Section 63.6(e... by the standard at all times, including during any period of startup, shutdown, or malfunction...)(3) of subpart A of this part, the owner or operator shall develop a written startup, shutdown, and...

40 CFR 63.2250 - What are the general requirements?

Code of Federal Regulations, 2011 CFR

2011-07-01

... periods of process unit or control device startup, shutdown, and malfunction; prior to process unit initial startup; and during the routine control device maintenance exemption specified in § 63.2251. The... are not operating, or during periods of startup, shutdown, and malfunction. Startup and shutdown...

40 CFR 63.2250 - What are the general requirements?

Code of Federal Regulations, 2010 CFR

2010-07-01

... periods of process unit or control device startup, shutdown, and malfunction; prior to process unit initial startup; and during the routine control device maintenance exemption specified in § 63.2251. The... are not operating, or during periods of startup, shutdown, and malfunction. Startup and shutdown...

40 CFR 63.1164 - Reporting requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... written extension of compliance. (c) Periodic startup, shutdown, and malfunction reports. Section 63.6(e... by the standard at all times, including during any period of startup, shutdown, or malfunction...)(3) of subpart A of this part, the owner or operator shall develop a written startup, shutdown, and...

40 CFR 63.1164 - Reporting requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... written extension of compliance. (c) Periodic startup, shutdown, and malfunction reports. Section 63.6(e... by the standard at all times, including during any period of startup, shutdown, or malfunction...)(3) of subpart A of this part, the owner or operator shall develop a written startup, shutdown, and...

40 CFR 63.2862 - What records must I keep?

Code of Federal Regulations, 2011 CFR

2011-07-01

...) initial startup period or the § 63.2850(e)(2) malfunction period. Complete both plans before the... such as normal operation, nonoperating, initial startup period, malfunction period, or exempt operation... inventory. (ii) The operating status of your source such as normal operation, nonoperating, initial startup...

40 CFR 63.2862 - What records must I keep?

Code of Federal Regulations, 2010 CFR

2010-07-01

...) initial startup period or the § 63.2850(e)(2) malfunction period. Complete both plans before the... such as normal operation, nonoperating, initial startup period, malfunction period, or exempt operation... inventory. (ii) The operating status of your source such as normal operation, nonoperating, initial startup...

49 CFR 234.103 - Timely response to report of malfunction.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Timely response to report of malfunction. 234.103 Section 234.103 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SIGNAL SYSTEM SAFETY AND STATE ACTION PLANS Response...

49 CFR 234.103 - Timely response to report of malfunction.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Timely response to report of malfunction. 234.103 Section 234.103 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SIGNAL SYSTEM SAFETY AND STATE ACTION PLANS Response...

Using statistical anomaly detection models to find clinical decision support malfunctions.

PubMed

Ray, Soumi; McEvoy, Dustin S; Aaron, Skye; Hickman, Thu-Trang; Wright, Adam

2018-05-11

Malfunctions in Clinical Decision Support (CDS) systems occur due to a multitude of reasons, and often go unnoticed, leading to potentially poor outcomes. Our goal was to identify malfunctions within CDS systems. We evaluated 6 anomaly detection models: (1) Poisson Changepoint Model, (2) Autoregressive Integrated Moving Average (ARIMA) Model, (3) Hierarchical Divisive Changepoint (HDC) Model, (4) Bayesian Changepoint Model, (5) Seasonal Hybrid Extreme Studentized Deviate (SHESD) Model, and (6) E-Divisive with Median (EDM) Model and characterized their ability to find known anomalies. We analyzed 4 CDS alerts with known malfunctions from the Longitudinal Medical Record (LMR) and Epic® (Epic Systems Corporation, Madison, WI, USA) at Brigham and Women's Hospital, Boston, MA. The 4 rules recommend lead testing in children, aspirin therapy in patients with coronary artery disease, pneumococcal vaccination in immunocompromised adults and thyroid testing in patients taking amiodarone. Poisson changepoint, ARIMA, HDC, Bayesian changepoint and the SHESD model were able to detect anomalies in an alert for lead screening in children and in an alert for pneumococcal conjugate vaccine in immunocompromised adults. EDM was able to detect anomalies in an alert for monitoring thyroid function in patients on amiodarone. Malfunctions/anomalies occur frequently in CDS alert systems. It is important to be able to detect such anomalies promptly. Anomaly detection models are useful tools to aid such detections.

Occupant Injury Severity and Accident Causes in Helicopter Emergency Medical Services (1983-2014).

PubMed

Boyd, Douglas D; Macchiarella, Nickolas D

2016-01-01

Helicopter emergency medical services (HEMS) transport critically ill patients to/between emergency care facilities and operate in a hazardous environment: the destination site is often encumbered with obstacles, difficult to visualize at night, and lack instrument approaches for degraded visibility. The study objectives were to determine 1) HEMS accident rates and causes; 2) occupant injury severity profiles; and 3) whether accident aircraft were certified to the more stringent crashworthiness standards implemented two decades ago. The National Transportation Safety Board (NTSB) aviation accident database was used to identify HEMS mishaps for the years spanning 1983-2014. Contingency tables (Pearson Chi-square or Fisher's exact test) were used to determine differences in proportions. A generalized linear model (Poisson distribution) was used to determine if accident rates differed over time. While the HEMS accident rate decreased by 71% across the study period, the fraction of fatal accidents (36-50%) and the injury severity profiles were unchanged. None of the accident aircraft fully satisfied the current crashworthiness standards. Failure to clear obstacles and visual-to-instrument flight, the most frequent accident causes (37 and 26%, respectively), showed a downward trend, whereas accidents ascribed to aircraft malfunction showed an upward trend over time. HEMS operators should consider updating their fleet to the current, more stringent crashworthiness standards in an attempt to reduce injury severity. Additionally, toward further mitigating accidents ascribed to inadvertent visual-to-instrument conditions, HEMS aircraft should be avionics-equipped for instrument flight rules flight.

Machine assisted histogram classification

NASA Astrophysics Data System (ADS)

Benyó, B.; Gaspar, C.; Somogyi, P.

2010-04-01

LHCb is one of the four major experiments under completion at the Large Hadron Collider (LHC). Monitoring the quality of the acquired data is important, because it allows the verification of the detector performance. Anomalies, such as missing values or unexpected distributions can be indicators of a malfunctioning detector, resulting in poor data quality. Spotting faulty or ageing components can be either done visually using instruments, such as the LHCb Histogram Presenter, or with the help of automated tools. In order to assist detector experts in handling the vast monitoring information resulting from the sheer size of the detector, we propose a graph based clustering tool combined with machine learning algorithm and demonstrate its use by processing histograms representing 2D hitmaps events. We prove the concept by detecting ion feedback events in the LHCb experiment's RICH subdetector.

A review of in-flight emergencies in the ASRS data base

NASA Technical Reports Server (NTRS)

Porter, R. F.

1981-01-01

A series of 154 in-flight emergencies as reported to the Aviation Safety Reporting System are described. The various types of emergencies are examined and an attempt is made to determine the human errors and other factors associated with each incident, as well as the measures taken to resolve the emergency. It is concluded that nearly one half of those emergencies reported were related to failure or malfunction of aircraft subsystems. Of all the emergencies, nearly one quarter were associated with power plant failure. Other frequently encountered emergency types are associated with operation in instrument meteorological conditions without appropriate clearance or qualification, and with low fuel state situations. Human error is prominently featured in many of the incidents, appearing in the actions of pilots and air traffic controllers.

14 CFR 21.3 - Reporting of failures, malfunctions, and defects.

Code of Federal Regulations, 2011 CFR

2011-01-01

... that has left its quality control system and that it determines could result in any of the occurrences... propeller control system. (5) A propeller or rotorcraft hub or blade structural failure. (6) Flammable fluid.... (11) Any structural or flight control system malfunction, defect, or failure which causes an...

40 CFR 63.7742 - How do I monitor and collect data to demonstrate continuous compliance?

Code of Federal Regulations, 2013 CFR

2013-07-01

... continuous compliance? (a) Except for monitoring malfunctions, associated repairs, and required quality assurance or control activities (including as applicable, calibration checks and required zero and span... emissions is operating. (b) You may not use data recorded during monitoring malfunctions, associated repairs...

40 CFR 63.7742 - How do I monitor and collect data to demonstrate continuous compliance?

Code of Federal Regulations, 2012 CFR

2012-07-01

... continuous compliance? (a) Except for monitoring malfunctions, associated repairs, and required quality assurance or control activities (including as applicable, calibration checks and required zero and span... emissions is operating. (b) You may not use data recorded during monitoring malfunctions, associated repairs...

40 CFR 63.7832 - How do I monitor and collect data to demonstrate continuous compliance?

Code of Federal Regulations, 2011 CFR

2011-07-01

... and collect data to demonstrate continuous compliance? (a) Except for monitoring malfunctions, out-of... control activities (including as applicable, calibration checks and required zero and span adjustments... source is operating. (b) You may not use data recorded during monitoring malfunctions, associated repairs...

40 CFR 63.7832 - How do I monitor and collect data to demonstrate continuous compliance?

Code of Federal Regulations, 2013 CFR

2013-07-01

... and collect data to demonstrate continuous compliance? (a) Except for monitoring malfunctions, out-of... control activities (including as applicable, calibration checks and required zero and span adjustments... source is operating. (b) You may not use data recorded during monitoring malfunctions, associated repairs...

40 CFR 63.2270 - How do I monitor and collect data to demonstrate continuous compliance?

Code of Federal Regulations, 2011 CFR

2011-07-01

... appropriate, monitor malfunctions, associated repairs, and required quality assurance or control activities... monitoring in continuous operation at all times that the process unit is operating. For purposes of calculating data averages, you must not use data recorded during monitoring malfunctions, associated repairs...

40 CFR 63.7742 - How do I monitor and collect data to demonstrate continuous compliance?

Code of Federal Regulations, 2010 CFR

2010-07-01

... continuous compliance? (a) Except for monitoring malfunctions, associated repairs, and required quality assurance or control activities (including as applicable, calibration checks and required zero and span... emissions is operating. (b) You may not use data recorded during monitoring malfunctions, associated repairs...

40 CFR 63.7832 - How do I monitor and collect data to demonstrate continuous compliance?

Code of Federal Regulations, 2014 CFR

2014-07-01

... and collect data to demonstrate continuous compliance? (a) Except for monitoring malfunctions, out-of... control activities (including as applicable, calibration checks and required zero and span adjustments... source is operating. (b) You may not use data recorded during monitoring malfunctions, associated repairs...

40 CFR 63.9633 - How do I monitor and collect data to demonstrate continuous compliance?

Code of Federal Regulations, 2013 CFR

2013-07-01

... continuous compliance? (a) Except for monitoring malfunctions, associated repairs, and required quality assurance or control activities (including as applicable, calibration checks and required zero and span... affected source is operating. (b) You may not use data recorded during monitoring malfunctions, associated...

40 CFR 63.2270 - How do I monitor and collect data to demonstrate continuous compliance?

Code of Federal Regulations, 2010 CFR

2010-07-01

... appropriate, monitor malfunctions, associated repairs, and required quality assurance or control activities... monitoring in continuous operation at all times that the process unit is operating. For purposes of calculating data averages, you must not use data recorded during monitoring malfunctions, associated repairs...

40 CFR 63.7832 - How do I monitor and collect data to demonstrate continuous compliance?

Code of Federal Regulations, 2010 CFR

2010-07-01

... and collect data to demonstrate continuous compliance? (a) Except for monitoring malfunctions, out-of... control activities (including as applicable, calibration checks and required zero and span adjustments... source is operating. (b) You may not use data recorded during monitoring malfunctions, associated repairs...

40 CFR 63.7742 - How do I monitor and collect data to demonstrate continuous compliance?

Code of Federal Regulations, 2014 CFR

2014-07-01

... continuous compliance? (a) Except for monitoring malfunctions, associated repairs, and required quality assurance or control activities (including as applicable, calibration checks and required zero and span... emissions is operating. (b) You may not use data recorded during monitoring malfunctions, associated repairs...

40 CFR 63.7742 - How do I monitor and collect data to demonstrate continuous compliance?

Code of Federal Regulations, 2011 CFR

2011-07-01

... continuous compliance? (a) Except for monitoring malfunctions, associated repairs, and required quality assurance or control activities (including as applicable, calibration checks and required zero and span... emissions is operating. (b) You may not use data recorded during monitoring malfunctions, associated repairs...

40 CFR 63.7832 - How do I monitor and collect data to demonstrate continuous compliance?

Code of Federal Regulations, 2012 CFR

2012-07-01

... and collect data to demonstrate continuous compliance? (a) Except for monitoring malfunctions, out-of... control activities (including as applicable, calibration checks and required zero and span adjustments... source is operating. (b) You may not use data recorded during monitoring malfunctions, associated repairs...

40 CFR 63.9633 - How do I monitor and collect data to demonstrate continuous compliance?

Code of Federal Regulations, 2010 CFR

2010-07-01

... continuous compliance? (a) Except for monitoring malfunctions, associated repairs, and required quality assurance or control activities (including as applicable, calibration checks and required zero and span... affected source is operating. (b) You may not use data recorded during monitoring malfunctions, associated...

40 CFR 63.9633 - How do I monitor and collect data to demonstrate continuous compliance?

Code of Federal Regulations, 2014 CFR

2014-07-01

... continuous compliance? (a) Except for monitoring malfunctions, associated repairs, and required quality assurance or control activities (including as applicable, calibration checks and required zero and span... affected source is operating. (b) You may not use data recorded during monitoring malfunctions, associated...

40 CFR 63.9633 - How do I monitor and collect data to demonstrate continuous compliance?

Code of Federal Regulations, 2012 CFR

2012-07-01

... continuous compliance? (a) Except for monitoring malfunctions, associated repairs, and required quality assurance or control activities (including as applicable, calibration checks and required zero and span... affected source is operating. (b) You may not use data recorded during monitoring malfunctions, associated...

Person-Organization Pairing

ERIC Educational Resources Information Center

Scirotino, P. T.; Madden, Denis

1973-01-01

Malfunctioning organizations do not facilitate the accomplishment of the purposes of their members in a number of ways and for a number of reasons. This paper used Maslow's hierarchy of needs model in an attempt to describe one view of that malfunction. Leadership is examined briefly as a functioning organization's facilitating arrangement.…

40 CFR 60.2120 - Affirmative Defense for Exceedance of an Emission Limit During Malfunction.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Standards of Performance for Commercial and Industrial Solid Waste Incineration Units Emission Limitations... monitoring methods and engineering judgment, the amount of excess emissions that were the result of the... malfunction event at issue. The analysis shall also specify, using best monitoring methods and engineering...

40 CFR 63.8635 - What reports must I submit and when?

Code of Federal Regulations, 2012 CFR

2012-07-01

... of report and beginning and ending dates of the reporting period. (4) If you had a startup, shutdown... section. This includes periods of startup, shutdown, malfunction, and routine control device maintenance... (e)(1) through (13) of this section. This includes periods of startup, shutdown, malfunction, and...

40 CFR 63.7555 - What records must I keep?

Code of Federal Regulations, 2010 CFR

2010-07-01

... (v) related to startup, shutdown, and malfunction. (3) Records of performance tests, fuel analyses... the deviation occurred during a period of startup, shutdown, or malfunction or during another period... monthly fuel use by each boiler or process heater, including the type(s) of fuel and amount(s) used. (2...

40 CFR 63.7555 - What records must I keep?

Code of Federal Regulations, 2012 CFR

2012-07-01

... (v) related to startup, shutdown, and malfunction. (3) Records of performance tests, fuel analyses... the deviation occurred during a period of startup, shutdown, or malfunction or during another period... monthly fuel use by each boiler or process heater, including the type(s) of fuel and amount(s) used. (2...

40 CFR 63.9050 - What reports must I submit and when?

Code of Federal Regulations, 2012 CFR

2012-07-01

... of the reporting period. (4) If you had a startup, shutdown, or malfunction during the reporting period and you took actions consistent with your startup, shutdown, and malfunction plan, the compliance... period. This description shall include the type of maintenance performed and the total number of hours...

40 CFR 63.8635 - What reports must I submit and when?

Code of Federal Regulations, 2013 CFR

2013-07-01

... of report and beginning and ending dates of the reporting period. (4) If you had a startup, shutdown... section. This includes periods of startup, shutdown, malfunction, and routine control device maintenance... (e)(1) through (13) of this section. This includes periods of startup, shutdown, malfunction, and...

40 CFR 63.7555 - What records must I keep?

Code of Federal Regulations, 2011 CFR

2011-07-01

... (v) related to startup, shutdown, and malfunction. (3) Records of performance tests, fuel analyses... the deviation occurred during a period of startup, shutdown, or malfunction or during another period... monthly fuel use by each boiler or process heater, including the type(s) of fuel and amount(s) used. (2...

40 CFR 63.9050 - What reports must I submit and when?

Code of Federal Regulations, 2011 CFR

2011-07-01

... of the reporting period. (4) If you had a startup, shutdown, or malfunction during the reporting period and you took actions consistent with your startup, shutdown, and malfunction plan, the compliance... period. This description shall include the type of maintenance performed and the total number of hours...

40 CFR 63.9050 - What reports must I submit and when?

Code of Federal Regulations, 2013 CFR

2013-07-01

... of the reporting period. (4) If you had a startup, shutdown, or malfunction during the reporting period and you took actions consistent with your startup, shutdown, and malfunction plan, the compliance... period. This description shall include the type of maintenance performed and the total number of hours...

40 CFR 63.9050 - What reports must I submit and when?

Code of Federal Regulations, 2014 CFR

2014-07-01

... of the reporting period. (4) If you had a startup, shutdown, or malfunction during the reporting period and you took actions consistent with your startup, shutdown, and malfunction plan, the compliance... period. This description shall include the type of maintenance performed and the total number of hours...

40 CFR 63.8635 - What reports must I submit and when?

Code of Federal Regulations, 2014 CFR

2014-07-01

... of report and beginning and ending dates of the reporting period. (4) If you had a startup, shutdown... section. This includes periods of startup, shutdown, malfunction, and routine control device maintenance... (e)(1) through (13) of this section. This includes periods of startup, shutdown, malfunction, and...

40 CFR 63.8635 - What reports must I submit and when?

Code of Federal Regulations, 2011 CFR

2011-07-01

... of report and beginning and ending dates of the reporting period. (4) If you had a startup, shutdown... section. This includes periods of startup, shutdown, malfunction, and routine control device maintenance... (e)(1) through (13) of this section. This includes periods of startup, shutdown, malfunction, and...

33 CFR 149.125 - What are the requirements for the malfunction detection system?

Code of Federal Regulations, 2011 CFR

2011-07-01

...) Each oil and natural gas system, between a pumping platform complex and the shore, must have a system... malfunction detection system? 149.125 Section 149.125 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: DESIGN, CONSTRUCTION, AND EQUIPMENT...

33 CFR 149.125 - What are the requirements for the malfunction detection system?

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Each oil and natural gas system, between a pumping platform complex and the shore, must have a system... malfunction detection system? 149.125 Section 149.125 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: DESIGN, CONSTRUCTION, AND EQUIPMENT...

40 CFR 63.9375 - What definitions apply to this subpart?

Code of Federal Regulations, 2012 CFR

2012-07-01

... malfunction, regardless or whether or not such failure is permitted by this subpart. Engine means any internal.... Malfunction means any sudden, infrequent, and not reasonably preventable failure of air pollution control... potential to cause, the emission limitations in an applicable standard to be exceeded. Failures that are...

40 CFR 63.9375 - What definitions apply to this subpart?

Code of Federal Regulations, 2014 CFR

2014-07-01

... malfunction, regardless or whether or not such failure is permitted by this subpart. Engine means any internal.... Malfunction means any sudden, infrequent, and not reasonably preventable failure of air pollution control... potential to cause, the emission limitations in an applicable standard to be exceeded. Failures that are...

40 CFR 63.9375 - What definitions apply to this subpart?

Code of Federal Regulations, 2013 CFR

2013-07-01

... malfunction, regardless or whether or not such failure is permitted by this subpart. Engine means any internal.... Malfunction means any sudden, infrequent, and not reasonably preventable failure of air pollution control... potential to cause, the emission limitations in an applicable standard to be exceeded. Failures that are...

40 CFR 63.9375 - What definitions apply to this subpart?

Code of Federal Regulations, 2011 CFR

2011-07-01

... malfunction, regardless or whether or not such failure is permitted by this subpart. Engine means any internal.... Malfunction means any sudden, infrequent, and not reasonably preventable failure of air pollution control... potential to cause, the emission limitations in an applicable standard to be exceeded. Failures that are...

77 FR 20746 - Airworthiness Directives; Bombardier, Inc. Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-06

...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for certain Bombardier, Inc. Model CL-600.../ malfunctioning of the left-hand engine thrust control mechanism. This proposed AD would require modifying the left-hand engine upper core- cowl. We are proposing this AD to prevent jamming/malfunctioning of the...

System Definition of the James Webb Space Telescope (JWST) Integrated Science Instrument Module (ISIM)

NASA Technical Reports Server (NTRS)

Lundquist, Ray; Aymergen, Cagatay; VanCampen, Julie; Abell, James; Smith, Miles; Driggers, Phillip

2008-01-01

The Integrated Science Instrument Module (ISIM) for the James Webb Space Telescope (JWST) provides the critical functions and the environment for the four science instruments on JWST. This complex system development across many international organizations presents unique challenges and unique solutions. Here we describe how the requirement flow has been coordinated through the documentation system, how the tools and processes are used to minimize impact to the development of the affected interfaces, how the system design has matured, how the design review process operates, and how the system implementation is managed through reporting to ensure a truly world class scientific instrument compliment is created as the final product.

Cerebrospinal fluid eosinophilia and sterile shunt malfunction.

PubMed

Traynelis, V C; Powell, R G; Koss, W; Schochet, S S; Kaufman, H H

1988-11-01

Cerebrospinal fluid (CSF) eosinophilia is a rare finding most often associated with central nervous system inflammatory processes, including parasitic, bacterial, and mycotic infections. It has also been seen as an allergic phenomenon. We present two cases of CSF eosinophilia occurring concurrently with sterile shunt malfunction. We speculate that CSF eosinophilia in our patients might have resulted from an allergic response to a foreign material such as suture, surgical glove powder, hair, cotton fibers, antibiotics, or silicone rubber. The incidence of sterile CSF eosinophilia after shunting is not known. Information concerning the role of eosinophilia in the development of shunt malfunctions is also lacking. An increased awareness of this possibility and further investigation are warranted.

An application of adaptive learning to malfunction recovery

NASA Technical Reports Server (NTRS)

Cruz, R. E.

1986-01-01

A self-organizing controller is developed for a simplified two-dimensional aircraft model. The Controller learns how to pilot the aircraft through a navigational mission without exceeding pre-established position and velocity limits. The controller pilots the aircraft by activating one of eight directional actuators at all times. By continually monitoring the aircraft's position and velocity with respect to the mission, the controller progressively modifies its decision rules to improve the aircraft's performance. When the controller has learned how to pilot the aircraft, two actuators fail permanently. Despite this malfunction, the controller regains proficiency at its original task. The experimental results reported show the controller's capabilities for self-organizing control, learning, and malfunction recovery.

Art, Meet Chemistry; Chemistry, Meet Art: Case Studies, Current Literature, and Instrumental Methods Combined to Create a Hands-On Experience for Nonmajors and Instrumental Analysis Students

ERIC Educational Resources Information Center

Nivens, Delana A.; Padgett, Clifford W.; Chase, Jeffery M.; Verges, Katie J.; Jamieson, Deborah S.

2010-01-01

Case studies and current literature are combined with spectroscopic analysis to provide a unique chemistry experience for art history students and to provide a unique inquiry-based laboratory experiment for analytical chemistry students. The XRF analysis method was used to demonstrate to nonscience majors (art history students) a powerful…

40 CFR 1048.110 - How must my engines diagnose malfunctions?

Code of Federal Regulations, 2013 CFR

2013-07-01

... control of air-fuel ratios: (a) Equip your engines with a diagnostic system. Starting in the 2007 model... malfunction whenever the air-fuel ratio does not cross stoichiometry for one minute of intended closed-loop operation. You may use other diagnostic strategies if we approve them in advance. (2) If the protocol...

40 CFR 1048.110 - How must my engines diagnose malfunctions?

Code of Federal Regulations, 2012 CFR

2012-07-01

... control of air-fuel ratios: (a) Equip your engines with a diagnostic system. Starting in the 2007 model... malfunction whenever the air-fuel ratio does not cross stoichiometry for one minute of intended closed-loop operation. You may use other diagnostic strategies if we approve them in advance. (2) If the protocol...

40 CFR 1048.110 - How must my engines diagnose malfunctions?

Code of Federal Regulations, 2014 CFR

2014-07-01

... control of air-fuel ratios: (a) Equip your engines with a diagnostic system. Starting in the 2007 model... malfunction whenever the air-fuel ratio does not cross stoichiometry for one minute of intended closed-loop operation. You may use other diagnostic strategies if we approve them in advance. (2) If the protocol...

40 CFR 63.10001 - Affirmative defense for exceedence of emission limit during malfunction.

Code of Federal Regulations, 2012 CFR

2012-07-01

... the standards set forth in § 63.9991 you may assert an affirmative defense to a claim for civil... best monitoring methods and engineering judgment, the amount of excess emissions that were the result... of an affirmative defense to civil penalties for that malfunction. The owner or operator seeking to...

40 CFR 63.10001 - Affirmative defense for exceedence of emission limit during malfunction.

Code of Federal Regulations, 2014 CFR

2014-07-01

... the standards set forth in § 63.9991 you may assert an affirmative defense to a claim for civil... best monitoring methods and engineering judgment, the amount of excess emissions that were the result... of an affirmative defense to civil penalties for that malfunction. The owner or operator seeking to...

Dealing with Malfunction: Locus of Control in Web-Conferencing

ERIC Educational Resources Information Center

Klebl, Michael

2014-01-01

This paper considers how students deal with malfunctions that occur during the use of web conferencing systems in learning arrangements. In a survey among participants in online courses that make use of a web-conferencing system (N = 129), the relationship between a preference for internal or external locus of control and the perception of…

40 CFR Table 14 to Subpart Wwww of... - Requirements for Reports

Code of Federal Regulations, 2010 CFR

2010-07-01

....5910(b). c. The information in § 63.10(d)(5)(i) if you had a startup, shutdown or malfunction during the reporting period, and you took actions consistent with your startup, shutdown, and malfunction plan Semiannually according to the requirements in § 63.5910(b). 2. An immediate startup, shutdown, and...

40 CFR Table 15 to Subpart Xxxx of... - Requirements for Reports

Code of Federal Regulations, 2014 CFR

2014-07-01

... reporting in § 63.6010(f). c. If you had a startup, shutdown or malfunction during the reporting period and you took actions consistent with your startup, shutdown, and malfunction plan, the compliance report....6010(b), unless you meet the requirements for annual reporting in § 63.6010(f). 2. Immediate startup...

40 CFR Table 1 to Subpart Aaaa of... - Applicability of NESHAP General Provisions to Subpart AAAA

Code of Federal Regulations, 2012 CFR

2012-07-01

... constructed, and reconstructed sources 63.6(e) Operation and maintenance requirements, startup, shutdown and... taken during a startup, shutdown and malfunction plan are consistent with the procedures in the startup, shutdown and malfunction plan, this information shall be included in a semi-annual startup, shutdown and...

40 CFR 63.7720 - What are my general requirements for complying with this subpart?

Code of Federal Regulations, 2012 CFR

2012-07-01

... operation and maintenance requirements in this subpart at all times, except during periods of startup... process and emissions control equipment. (c) You must develop a written startup, shutdown, and malfunction plan according to the provisions in § 63.6(e)(3). The startup, shutdown, and malfunction plan also must...

40 CFR Table 1 to Subpart Aaaa of... - Applicability of NESHAP General Provisions to Subpart AAAA

Code of Federal Regulations, 2014 CFR

2014-07-01

... constructed, and reconstructed sources 63.6(e) Operation and maintenance requirements, startup, shutdown and... taken during a startup, shutdown and malfunction plan are consistent with the procedures in the startup, shutdown and malfunction plan, this information shall be included in a semi-annual startup, shutdown and...

40 CFR Table 14 to Subpart Wwww of... - Requirements for Reports

Code of Federal Regulations, 2011 CFR

2011-07-01

....5910(b). c. The information in § 63.10(d)(5)(i) if you had a startup, shutdown or malfunction during the reporting period, and you took actions consistent with your startup, shutdown, and malfunction plan Semiannually according to the requirements in § 63.5910(b). 2. An immediate startup, shutdown, and...

40 CFR 63.7720 - What are my general requirements for complying with this subpart?

Code of Federal Regulations, 2010 CFR

2010-07-01

... operation and maintenance requirements in this subpart at all times, except during periods of startup... process and emissions control equipment. (c) You must develop a written startup, shutdown, and malfunction plan according to the provisions in § 63.6(e)(3). The startup, shutdown, and malfunction plan also must...

40 CFR 60.2918 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 7 2013-07-01 2013-07-01 false What happens during periods of startup... Emission Limitations and Operating Limits § 60.2918 What happens during periods of startup, shutdown, and malfunction? The emission limitations and operating limits apply at all times except during OSWI unit startups...

40 CFR 63.7720 - What are my general requirements for complying with this subpart?

Code of Federal Regulations, 2011 CFR

2011-07-01

... operation and maintenance requirements in this subpart at all times, except during periods of startup... process and emissions control equipment. (c) You must develop a written startup, shutdown, and malfunction plan according to the provisions in § 63.6(e)(3). The startup, shutdown, and malfunction plan also must...

40 CFR Table 15 to Subpart Xxxx of... - Requirements for Reports

Code of Federal Regulations, 2012 CFR

2012-07-01

... reporting in § 63.6010(f). c. If you had a startup, shutdown or malfunction during the reporting period and you took actions consistent with your startup, shutdown, and malfunction plan, the compliance report....6010(b), unless you meet the requirements for annual reporting in § 63.6010(f). 2. Immediate startup...

40 CFR 63.7720 - What are my general requirements for complying with this subpart?

Code of Federal Regulations, 2013 CFR

2013-07-01

... operation and maintenance requirements in this subpart at all times, except during periods of startup... process and emissions control equipment. (c) You must develop a written startup, shutdown, and malfunction plan according to the provisions in § 63.6(e)(3). The startup, shutdown, and malfunction plan also must...

40 CFR Table 15 to Subpart Xxxx of... - Requirements for Reports

Code of Federal Regulations, 2013 CFR

2013-07-01

....6010(f). c. If you had a startup, shutdown or malfunction during the reporting period and you took actions consistent with your startup, shutdown, and malfunction plan, the compliance report must include... you meet the requirements for annual reporting in § 63.6010(f). 2. Immediate startup, shutdown, and...

40 CFR 63.7720 - What are my general requirements for complying with this subpart?

Code of Federal Regulations, 2014 CFR

2014-07-01

... operation and maintenance requirements in this subpart at all times, except during periods of startup... process and emissions control equipment. (c) You must develop a written startup, shutdown, and malfunction plan according to the provisions in § 63.6(e)(3). The startup, shutdown, and malfunction plan also must...

40 CFR Table 1 to Subpart Aaaa of... - Applicability of NESHAP General Provisions to Subpart AAAA

Code of Federal Regulations, 2013 CFR

2013-07-01

... constructed, and reconstructed sources 63.6(e) Operation and maintenance requirements, startup, shutdown and... taken during a startup, shutdown and malfunction plan are consistent with the procedures in the startup, shutdown and malfunction plan, this information shall be included in a semi-annual startup, shutdown and...

40 CFR 60.2918 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 7 2014-07-01 2014-07-01 false What happens during periods of startup... Emission Limitations and Operating Limits § 60.2918 What happens during periods of startup, shutdown, and malfunction? The emission limitations and operating limits apply at all times except during OSWI unit startups...

40 CFR 63.9641 - What reports must I submit and when?

Code of Federal Regulations, 2014 CFR

2014-07-01

... and ending dates of the reporting period. (4) If you had a startup, shutdown, or malfunction during the reporting period and you took actions consistent with your startup, shutdown, and malfunction plan... information in paragraphs (b)(7)(i) and (ii) of this section. This includes periods of startup, shutdown, and...

40 CFR 63.1211 - What are the recordkeeping and reporting requirements?

Code of Federal Regulations, 2010 CFR

2010-07-01

... compliance date granted under § 63.6(i). 63.10(d)(5)(i) Periodic startup, shutdown, and malfunction reports. 63.10(d)(5)(ii) Immediate startup, shutdown, and malfunction reports. 63.10(e)(3) Excessive emissions and continuous monitoring system performance report and summary report. 63.1206(c)(2)(ii)(B) Startup...

40 CFR 63.1211 - What are the recordkeeping and reporting requirements?

Code of Federal Regulations, 2012 CFR

2012-07-01

... compliance date granted under § 63.6(i). 63.10(d)(5)(i) Periodic startup, shutdown, and malfunction reports. 63.10(d)(5)(ii) Immediate startup, shutdown, and malfunction reports. 63.10(e)(3) Excessive emissions and continuous monitoring system performance report and summary report. 63.1206(c)(2)(ii)(B) Startup...

40 CFR 63.9641 - What reports must I submit and when?

Code of Federal Regulations, 2012 CFR

2012-07-01

... and ending dates of the reporting period. (4) If you had a startup, shutdown, or malfunction during the reporting period and you took actions consistent with your startup, shutdown, and malfunction plan... information in paragraphs (b)(7)(i) and (ii) of this section. This includes periods of startup, shutdown, and...

40 CFR 63.1211 - What are the recordkeeping and reporting requirements?

Code of Federal Regulations, 2014 CFR

2014-07-01

... compliance date granted under § 63.6(i). 63.10(d)(5)(i) Periodic startup, shutdown, and malfunction reports. 63.10(d)(5)(ii) Immediate startup, shutdown, and malfunction reports. 63.10(e)(3) Excessive emissions and continuous monitoring system performance report and summary report. 63.1206(c)(2)(ii)(B) Startup...

40 CFR 63.9641 - What reports must I submit and when?

Code of Federal Regulations, 2013 CFR

2013-07-01

... and ending dates of the reporting period. (4) If you had a startup, shutdown, or malfunction during the reporting period and you took actions consistent with your startup, shutdown, and malfunction plan... information in paragraphs (b)(7)(i) and (ii) of this section. This includes periods of startup, shutdown, and...

40 CFR 63.1211 - What are the recordkeeping and reporting requirements?

Code of Federal Regulations, 2013 CFR

2013-07-01

... compliance date granted under § 63.6(i). 63.10(d)(5)(i) Periodic startup, shutdown, and malfunction reports. 63.10(d)(5)(ii) Immediate startup, shutdown, and malfunction reports. 63.10(e)(3) Excessive emissions and continuous monitoring system performance report and summary report. 63.1206(c)(2)(ii)(B) Startup...

40 CFR 63.1211 - What are the recordkeeping and reporting requirements?

Code of Federal Regulations, 2011 CFR

2011-07-01

... compliance date granted under § 63.6(i). 63.10(d)(5)(i) Periodic startup, shutdown, and malfunction reports. 63.10(d)(5)(ii) Immediate startup, shutdown, and malfunction reports. 63.10(e)(3) Excessive emissions and continuous monitoring system performance report and summary report. 63.1206(c)(2)(ii)(B) Startup...

40 CFR 63.9641 - What reports must I submit and when?

Code of Federal Regulations, 2011 CFR

2011-07-01

... and ending dates of the reporting period. (4) If you had a startup, shutdown, or malfunction during the reporting period and you took actions consistent with your startup, shutdown, and malfunction plan... information in paragraphs (b)(7)(i) and (ii) of this section. This includes periods of startup, shutdown, and...

NHEXAS PHASE I ARIZONA STUDY--STANDARD OPERATING PROCEDURE FOR ISOLATION OF MALFUNCTIONING OR DAMAGED EQUIPMENT (UA-G-2.0)

EPA Science Inventory

The purpose of this SOP is to identify and isolate malfunctioning or damaged equipment for the NHEXAS Arizona research project. This procedure was followed to ensure consistent data custody, storage, transfer and analysis of a high quality during the Arizona NHEXAS project and t...

40 CFR 270.235 - Options for incinerators, cement kilns, lightweight aggregate kilns, solid fuel boilers, liquid...

Code of Federal Regulations, 2010 CFR

2010-07-01

... Technology (MACT) Standards § 270.235 Options for incinerators, cement kilns, lightweight aggregate kilns... malfunction plan, design, and operating history. (2) Retain or add these permit requirements to the permit to... information including the source's startup, shutdown, and malfunction plan, design, and operating history; and...

40 CFR 63.6155 - What records must I keep?

Code of Federal Regulations, 2010 CFR

2010-07-01

... duration of each startup, shutdown, or malfunction as required in § 63.10(b)(2)(i). (4) Records of the occurrence and duration of each malfunction of the air pollution control equipment, if applicable, as... records required in Table 5 of this subpart to show continuous compliance with each operating limitation...

Intelligent Engine Systems Work Element 1.2: Malfunction and Operator Error Reduction

NASA Technical Reports Server (NTRS)

Wiseman, Matthew

2005-01-01

Jet engines, although highly reliable and safe, do experience malfunctions that cause flight delays, passenger stress, and in some cases, in conjunction with inappropriate crew response, contribute to airplane accidents. On rare occasions, the anomalous engine behavior is not recognized until it is too late for the pilots to do anything to prevent or mitigate the resulting engine malfunction causing in-flight shutdowns (IFSDs), aborted takeoffs (ATOs), or loss of thrust control (LOTC). In some cases, the crew response to a myriad of external stimuli and existing training procedures is the source of the problem mentioned above. The problem is the reduction of jet engine malfunctions (IFSDs, ATOs, and LOTC) and inappropriate crew response (PSM+ICR) through the use of evolving and advanced technologies. The solution is to develop the overall system health maintenance architecture, detection and accommodation technologies, processes, and enhanced crew interfaces that would enable a significant reduction in IFSDs, ATOs, and LOTC. This program defines requirements and proposes a preliminary design concept of an architecture that enables the realization of the solution.

Vagal Nerve Stimulator Malfunction with Change in Neck Position: Case Report and Literature Review.

PubMed

D'Agostino, Erin; Makler, Vyacheslav; Bauer, David F

2018-06-01

Vagal nerve stimulation is a safe and well-tolerated treatment for drug-resistant epilepsy. Complications and failure of the device can result from lead fracture, device malfunction, disconnection, or battery displacement and can result in a variety of symptoms. We present an interesting case of stimulator malfunction with increased impedance change seen only with a change in head position. The patient is a 25-year-old male with a vagal nerve stimulator (VNs) placed for medically refractory epilepsy who presented with neck pain and an electrical pulling sensation in his neck whenever he turned his head to the right. Initial interrogation of the VNs showed normal impedance. Subsequent interrogation with the patient's head turned found increased impedance only when the head was turned to the right. The patient had successful removal and replacement of the device with resolution of his preoperative complaints. Partial lead fracture was seen at explant. VNs malfunction can present in atypical ways. Positional maneuvers may help with its timely diagnosis. Copyright © 2018 Elsevier Inc. All rights reserved.

Epidemiology and natural history of central venous access device use and infusion pump function in the NO16966 trial.

PubMed

Chu, E; Haller, D; Cartwright, T; Twelves, C; Cassidy, J; Sun, W; Saif, M W; McKenna, E; Lee, S; Schmoll, H-J

2014-03-18

Central venous access devices in fluoropyrimidine therapy are associated with complications; however, reliable data are lacking regarding their natural history, associated complications and infusion pump performance in patients with metastatic colorectal cancer. We assessed device placement, use during treatment, associated clinical outcomes and infusion pump performance in the NO16966 trial. Device replacement was more common with FOLFOX-4 (5-fluorouracil (5-FU)+oxaliplatin) than XELOX (capecitabine+oxaliplatin) (14.1% vs 5.1%). Baseline device-associated events and post-baseline removal-/placement-related events occurred more frequently with FOLFOX-4 than XELOX (11.5% vs 2.4% and 8.5% vs 2.1%). Pump malfunctions, primarily infusion accelerations in 16% of patients, occurred within 1.6-4.3% of cycles. Fluoropyrimidine-associated grade 3/4 toxicity was increased in FOLFOX-4-treated patients experiencing a malfunction compared with those who did not (97 out of 155 vs 452 out of 825 patients), predominantly with increased grade 3/4 neutropenia (53.5% vs 39.8%). Febrile neutropenia rates were comparable between patient cohorts±malfunction. Efficacy outcomes were similar in patient cohorts±malfunction. Central venous access device removal or replacement was common and more frequent in patients receiving FOLFOX-4. Pump malfunctions were also common and were associated with increased rates of grade 3/4 haematological adverse events. Oral fluoropyrimidine-based regimens may be preferable to infusional 5-FU based on these findings.

Delusions as harmful malfunctioning beliefs.

PubMed

Miyazono, Kengo

2015-05-01

Delusional beliefs are typically pathological. Being pathological is clearly distinguished from being false or being irrational. Anna might falsely believe that his husband is having an affair but it might just be a simple mistake. Again, Sam might irrationally believe, without good evidence, that he is smarter than his colleagues, but it might just be a healthy self-deceptive belief. On the other hand, when a patient with brain damage caused by a car accident believes that his father was replaced by an imposter or another patient with schizophrenia believes that "The Organization" painted the shops on a street in red and green to convey a message, these beliefs are not merely false or irrational. They are pathological. What makes delusions pathological? This paper explores the negative features because of which delusional beliefs are pathological. First, I critically examine the proposals according to which delusional beliefs are pathological because of (1) their strangeness, (2) their extreme irrationality, (3) their resistance to folk psychological explanations or (4) impaired responsibility-grounding capacities of people with them. I present some counterexamples as well as theoretical problems for these proposals. Then, I argue, following Wakefield's harmful dysfunction analysis of disorder, that delusional beliefs are pathological because they involve some sorts of harmful malfunctions. In other words, they have a significant negative impact on wellbeing (=harmful) and, in addition, some psychological mechanisms, directly or indirectly related to them, fail to perform the jobs for which they were selected in the past (=malfunctioning). An objection to the proposal is that delusional beliefs might not involve any malfunctions. For example, they might be playing psychological defence functions properly. Another objection is that a harmful malfunction is not sufficient for something to be pathological. For example, false beliefs might involve some malfunctions according to teleosemantics, a popular naturalist account of mental content, but harmful false beliefs do not have to be pathological. I examine those objections in detail and show that they should be rejected after all. Copyright © 2014. Published by Elsevier Inc.

Cerebrospinal Fluid Lumbar Tapping Utilization for Suspected Ventriculoperitoneal Shunt Under-Drainage Malfunctions

PubMed Central

Lee, Jong-Beom; Ahn, Ho-Young; Lee, Hong-Jae; Yang, Ji-Ho; Yi, Jin-Seok; Lee, Il-Woo

2017-01-01

Objective The diagnosis of shunt malfunction can be challenging since neuroimaging results are not always correlated with clinical outcomes. The purpose of this study was to evaluate the efficacy of a simple, minimally invasive cerebrospinal fluid (CSF) lumbar tapping test that predicts shunt under-drainage in hydrocephalus patients. Methods We retrospectively reviewed the clinical and radiological features of 48 patients who underwent routine CSF lumbar tapping after ventriculoperitoneal shunt (VPS) operation using a programmable shunting device. We compared shunt valve opening pressure and CSF lumbar tapping pressure to check under-drainage. Results The mean pressure difference between valve opening pressure and CSF lumbar tapping pressure of all patients were 2.21±24.57 mmH2O. The frequency of CSF lumbar tapping was 2.06±1.26 times. Eighty five times lumbar tapping of 41 patients showed that their VPS function was normal which was consistent with clinical improvement and decreased ventricle size on computed tomography scan. The mean pressure difference in these patients was −3.69±19.20 mmH2O. The mean frequency of CSF lumbar tapping was 2.07±1.25 times. Fourteen cases of 10 patients revealed suspected VPS malfunction which were consistent with radiological results and clinical symptoms, defined as changes in ventricle size and no clinical improvement. The mean pressure difference was 38.07±23.58 mmH2O. The mean frequency of CSF lumbar tapping was 1.44±1.01 times. Pressure difference greater than 35 mmH2O was shown in 2.35% of the normal VPS function group (2 of 85) whereas it was shown in 64.29% of the suspected VPS malfunction group (9 of 14). The difference was statistically significant (p=0.000001). Among 10 patients with under-drainage, 5 patients underwent shunt revision. The causes of the shunt malfunction included 3 cases of proximal occlusion and 2 cases of distal obstruction and valve malfunction. Conclusion Under-drainage of CSF should be suspected if CSF lumbar tapping pressure is 35 mmH2O higher than the valve opening pressure and shunt malfunction evaluation or adjustment of the valve opening pressure should be made. PMID:28061484

Trick Simulation Environment 07

NASA Technical Reports Server (NTRS)

Lin, Alexander S.; Penn, John M.

2012-01-01

The Trick Simulation Environment is a generic simulation toolkit used for constructing and running simulations. This release includes a Monte Carlo analysis simulation framework and a data analysis package. It produces all auto documentation in XML. Also, the software is capable of inserting a malfunction at any point during the simulation. Trick 07 adds variable server output options and error messaging and is capable of using and manipulating wide characters for international support. Wide character strings are available as a fundamental type for variables processed by Trick. A Trick Monte Carlo simulation uses a statistically generated, or predetermined, set of inputs to iteratively drive the simulation. Also, there is a framework in place for optimization and solution finding where developers may iteratively modify the inputs per run based on some analysis of the outputs. The data analysis package is capable of reading data from external simulation packages such as MATLAB and Octave, as well as the common comma-separated values (CSV) format used by Excel, without the use of external converters. The file formats for MATLAB and Octave were obtained from their documentation sets, and Trick maintains generic file readers for each format. XML tags store the fields in the Trick header comments. For header files, XML tags for structures and enumerations, and the members within are stored in the auto documentation. For source code files, XML tags for each function and the calling arguments are stored in the auto documentation. When a simulation is built, a top level XML file, which includes all of the header and source code XML auto documentation files, is created in the simulation directory. Trick 07 provides an XML to TeX converter. The converter reads in header and source code XML documentation files and converts the data to TeX labels and tables suitable for inclusion in TeX documents. A malfunction insertion capability allows users to override the value of any simulation variable, or call a malfunction job, at any time during the simulation. Users may specify conditions, use the return value of a malfunction trigger job, or manually activate a malfunction. The malfunction action may consist of executing a block of input file statements in an action block, setting simulation variable values, call a malfunction job, or turn on/off simulation jobs.

Perception of Competence in Middle School Physical Education: Instrument Development and Validation

ERIC Educational Resources Information Center

Scrabis-Fletcher, Kristin; Silverman, Stephen

2010-01-01

Perception of Competence (POC) has been studied extensively in physical activity (PA) research with similar instruments adapted for physical education (PE) research. Such instruments do not account for the unique PE learning environment. Therefore, an instrument was developed and the scores validated to measure POC in middle school PE. A…

But Does It Work? Reflective Activities, Learning Outcomes and Instrumental Learning in Continuing Professional Development

ERIC Educational Resources Information Center

Roessger, Kevin M.

2015-01-01

This paper examines the relationship between reflective practice and instrumental learning within the context of continuing professional development (CPD). It is argued that instrumental learning is a unique process of adult learning, and reflective practice's impact on learning outcomes in instrumental learning contexts remains unclear. A…

Portable 4.6 Micrometers Laser Absorption Spectrometer for Carbon Monoxide Monitoring and Fire Detection

NASA Technical Reports Server (NTRS)

Briggs, Ryan M.; Frez, Clifford; Forouhar, Siamak; May, Randy D.; Ruff, Gary A.

2013-01-01

The air quality aboard manned spacecraft must be continuously monitored to ensure crew safety and identify equipment malfunctions. In particular, accurate real-time monitoring of carbon monoxide (CO) levels helps to prevent chronic exposure and can also provide early detection of combustion-related hazards. For long-duration missions, environmental monitoring grows in importance, but the mass and volume of monitoring instruments must be minimized. Furthermore, environmental analysis beyond low-Earth orbit must be performed in-situ, as sample return becomes impractical. Due to their small size, low power draw, and performance reliability, semiconductor-laser-based absorption spectrometers are viable candidates for this purpose. To reduce instrument form factor and complexity, the emission wavelength of the laser source should coincide with strong fundamental absorption lines of the target gases, which occur in the 3 to 5 micrometers wavelength range for most combustion products of interest, thereby reducing the absorption path length required for low-level concentration measurements. To address the needs of current and future NASA missions, we have developed a prototype absorption spectrometer using a semiconductor quantum cascade laser source operating near 4.6 micrometers that can be used to detect low concentrations of CO with a compact single-pass absorption cell. In this study, we present the design of the prototype instrument and report on measurements of CO emissions from the combustion of a variety of aerospace plastics.

A Shipping Container-Based Sterile Processing Unit for Low Resources Settings

PubMed Central

2016-01-01

Deficiencies in the sterile processing of medical instruments contribute to poor outcomes for patients, such as surgical site infections, longer hospital stays, and deaths. In low resources settings, such as some rural and semi-rural areas and secondary and tertiary cities of developing countries, deficiencies in sterile processing are accentuated due to the lack of access to sterilization equipment, improperly maintained and malfunctioning equipment, lack of power to operate equipment, poor protocols, and inadequate quality control over inventory. Inspired by our sterile processing fieldwork at a district hospital in Sierra Leone in 2013, we built an autonomous, shipping-container-based sterile processing unit to address these deficiencies. The sterile processing unit, dubbed “the sterile box,” is a full suite capable of handling instruments from the moment they leave the operating room to the point they are sterile and ready to be reused for the next surgery. The sterile processing unit is self-sufficient in power and water and features an intake for contaminated instruments, decontamination, sterilization via non-electric steam sterilizers, and secure inventory storage. To validate efficacy, we ran tests of decontamination and sterilization performance. Results of 61 trials validate convincingly that our sterile processing unit achieves satisfactory outcomes for decontamination and sterilization and as such holds promise to support healthcare facilities in low resources settings. PMID:27007568

40 CFR Table 8 to Subpart Kkkkk of... - Applicability of General Provisions to Subpart KKKKK

Code of Federal Regulations, 2012 CFR

2012-07-01

..., Shutdown, and Malfunction Plan (SSMP) Requirement for startup, shutdown, and malfunction (SSM) and SSMP; content of SSMP Yes. § 63.6(f)(1) Compliance Except During SSM You must comply with emission standards at all times except during SSM Yes. § 63.6(f)(2)-(3) Methods for Determining Compliance Compliance based...

40 CFR Table 7 to Subpart Jjjjj of... - Applicability of General Provisions to Subpart JJJJJ

Code of Federal Regulations, 2014 CFR

2014-07-01

..., Shutdown, and Malfunction Plan (SSMP) Requirement for startup, shutdown, and malfunction (SSM) and SSMP; content of SSMP Yes. § 63.6(f)(1) Compliance Except During SSM You must comply with emission standards at all times except during SSM Yes. § 63.6(f)(2)-(3) Methods for Determining Compliance Compliance based...

40 CFR Table 7 to Subpart Jjjjj of... - Applicability of General Provisions to Subpart JJJJJ

Code of Federal Regulations, 2013 CFR

2013-07-01

..., Shutdown, and Malfunction Plan (SSMP) Requirement for startup, shutdown, and malfunction (SSM) and SSMP; content of SSMP Yes. § 63.6(f)(1) Compliance Except During SSM You must comply with emission standards at all times except during SSM Yes. § 63.6(f)(2)-(3) Methods for Determining Compliance Compliance based...

40 CFR Table 7 to Subpart Jjjjj of... - Applicability of General Provisions to Subpart JJJJJ

Code of Federal Regulations, 2011 CFR

2011-07-01

..., Shutdown, and Malfunction Plan (SSMP) Requirement for startup, shutdown, and malfunction (SSM) and SSMP; content of SSMP Yes. § 63.6(f)(1) Compliance Except During SSM You must comply with emission standards at all times except during SSM Yes. § 63.6(f)(2)-(3) Methods for Determining Compliance Compliance based...

40 CFR Table 10 to Subpart Ddddd... - Applicability of General Provisions to Subpart DDDDD

Code of Federal Regulations, 2012 CFR

2012-07-01

..., Shutdown, and Malfunction Plan (SSMP) Requirement for SSM and startup, shutdown, malfunction plan; and content of SSMP Yes. § 63.6(f)(1) Compliance Except During SSM Comply with emission standards at all times except during SSM Yes. § 63.6(f)(2)-(3) Methods for Determining Compliance Compliance based on...

40 CFR Table 8 to Subpart Kkkkk of... - Applicability of General Provisions to Subpart KKKKK

Code of Federal Regulations, 2014 CFR

2014-07-01

..., Shutdown, and Malfunction Plan (SSMP) Requirement for startup, shutdown, and malfunction (SSM) and SSMP; content of SSMP Yes. § 63.6(f)(1) Compliance Except During SSM You must comply with emission standards at all times except during SSM Yes. § 63.6(f)(2)-(3) Methods for Determining Compliance Compliance based...

40 CFR Table 8 to Subpart Kkkkk of... - Applicability of General Provisions to Subpart KKKKK

Code of Federal Regulations, 2013 CFR

2013-07-01

..., Shutdown, and Malfunction Plan (SSMP) Requirement for startup, shutdown, and malfunction (SSM) and SSMP; content of SSMP Yes. § 63.6(f)(1) Compliance Except During SSM You must comply with emission standards at all times except during SSM Yes. § 63.6(f)(2)-(3) Methods for Determining Compliance Compliance based...

40 CFR Table 10 to Subpart Ddddd... - Applicability of General Provisions to Subpart DDDDD

Code of Federal Regulations, 2011 CFR

2011-07-01

..., Shutdown, and Malfunction Plan (SSMP) Requirement for SSM and startup, shutdown, malfunction plan; and content of SSMP Yes. § 63.6(f)(1) Compliance Except During SSM Comply with emission standards at all times except during SSM Yes. § 63.6(f)(2)-(3) Methods for Determining Compliance Compliance based on...

40 CFR Table 8 to Subpart Kkkkk of... - Applicability of General Provisions to Subpart KKKKK

Code of Federal Regulations, 2011 CFR

2011-07-01

..., Shutdown, and Malfunction Plan (SSMP) Requirement for startup, shutdown, and malfunction (SSM) and SSMP; content of SSMP Yes. § 63.6(f)(1) Compliance Except During SSM You must comply with emission standards at all times except during SSM Yes. § 63.6(f)(2)-(3) Methods for Determining Compliance Compliance based...

40 CFR Table 7 to Subpart Jjjjj of... - Applicability of General Provisions to Subpart JJJJJ

Code of Federal Regulations, 2012 CFR

2012-07-01

..., Shutdown, and Malfunction Plan (SSMP) Requirement for startup, shutdown, and malfunction (SSM) and SSMP; content of SSMP Yes. § 63.6(f)(1) Compliance Except During SSM You must comply with emission standards at all times except during SSM Yes. § 63.6(f)(2)-(3) Methods for Determining Compliance Compliance based...

Clean-Burning Diesel Engines.

DTIC Science & Technology

1984-12-01

AFLRL No. 178 By oi Harry E. Dietzmann ,< Engines, Emissions.and Vehicle Research Division Southwest Research Institute San Antonio, Texas Prppared...the possibility of replacing the currently used electric forklift with diesel engine-powered forklifts in handling hazardous materials. Electric ...concern; however, these concerns may be amplified when the vehicle is operating under a malfunction mode. Malfunctions include simulating a plugged

40 CFR 63.3930 - What records must I keep?

Code of Federal Regulations, 2010 CFR

2010-07-01

... record of whether the deviation occurred during a period of startup, shutdown, or malfunction. (2) The records in § 63.6(e)(3)(iii) through (v) related to startup, shutdown, and malfunction. (3) The records... part 51 for a PTE and has a capture efficiency of 100 percent, as specified in § 63.3965(a). (5) For...

40 CFR 63.4130 - What records must I keep?

Code of Federal Regulations, 2010 CFR

2010-07-01

... period of startup, shutdown, or malfunction. (2) The records in § 63.6(e)(3)(iii) through (v) related to startup, shutdown, and malfunction. (3) The records required to show continuous compliance with each... of 100 percent, as specified in § 63.4165(a). (5) For each capture system that is not a PTE, the data...

40 CFR 63.4930 - What records must I keep?

Code of Federal Regulations, 2010 CFR

2010-07-01

... record of whether the deviation occurred during a period of startup, shutdown, or malfunction. (2) The records in § 63.6(e)(3)(iii) through (v) related to startup, shutdown, and malfunction. (3) The records... part 51 for a PTE and has a capture efficiency of 100 percent, as specified in § 63.4964(a). (5) For...

76 FR 24343 - Airworthiness Directives; Bombardier, Inc. Model DHC-8-101, -102, -103, -106, -201, -202, -301...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-02

... structural degradation possibly leading to the loss of the windshield during flight. Also, water could leak... during flight. Also, water could leak into the cockpit and cause either a malfunction or failure of the... the windshield during flight. Also, water could leak into the cockpit and cause either a malfunction...

U.S.-MEXICO BORDER PROGRAM ARIZONA BORDER STUDY--STANDARD OPERATING PROCEDURE FOR ISOLATION OF MALFUNCTIONING OR DAMAGED EQUIPMENT (UA-G-2.0)

EPA Science Inventory

The purpose of this SOP is to identify and isolate malfunctioning or damaged equipment for the Arizona Border Study. This procedure was followed to ensure consistent data custody, storage, transfer and analysis of a high quality during the Arizona NHEXAS project and the Border s...

40 CFR 60.5181 - How do I establish an affirmative defense for exceedance of an emission limit or standard during...

Code of Federal Regulations, 2013 CFR

2013-07-01

....5165, you may assert an affirmative defense to a claim for civil penalties for exceedances of emission... malfunction event at issue. The analysis shall also specify, using best monitoring methods and engineering... an affirmative defense to civil penalties for that malfunction. The owner or operator seeking to...

40 CFR 60.5181 - How do I establish an affirmative defense for exceedance of an emission limit or standard during...

Code of Federal Regulations, 2014 CFR

2014-07-01

....5165, you may assert an affirmative defense to a claim for civil penalties for exceedances of emission... malfunction event at issue. The analysis shall also specify, using best monitoring methods and engineering... an affirmative defense to civil penalties for that malfunction. The owner or operator seeking to...

75 FR 52263 - Airworthiness Directives; Empresa Brasileira de Aeronautica S.A. (EMBRAER) Model ERJ 170...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-25

...] during its retraction. In case of RAT failure or malfunction, it will not provide electrical power to... [the] aircraft, due to downlock pin not [being] pull[ed] during its retraction. In case of RAT failure... [being] pull[ed] during its retraction. In case of RAT failure or malfunction, it will not provide...

40 CFR 63.8248 - What other requirements must I meet?

Code of Federal Regulations, 2011 CFR

2011-07-01

... startup, shutdown, and malfunction. (2) You must report each instance in which you did not meet each work practice standard in § 63.8192 that applies to you. This includes periods of startup, shutdown, and... value was out of range. (b) Startups, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63...

40 CFR 63.5555 - How do I demonstrate continuous compliance with the emission limits, operating limits, and work...

Code of Federal Regulations, 2014 CFR

2014-07-01

... periods of startup, shutdown, and malfunction. These instances are deviations from the emission limits...), deviations that occur during a period of startup, shutdown, or malfunction are not violations if you... Administrator will determine whether deviations that occur during a period you identify as a startup, shutdown...

40 CFR 63.8248 - What other requirements must I meet?

Code of Federal Regulations, 2013 CFR

2013-07-01

... startup, shutdown, and malfunction. (2) You must report each instance in which you did not meet each work practice standard in § 63.8192 that applies to you. This includes periods of startup, shutdown, and... value was out of range. (b) Startups, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63...

40 CFR 63.5555 - How do I demonstrate continuous compliance with the emission limits, operating limits, and work...

Code of Federal Regulations, 2013 CFR

2013-07-01

... periods of startup, shutdown, and malfunction. These instances are deviations from the emission limits...), deviations that occur during a period of startup, shutdown, or malfunction are not violations if you... Administrator will determine whether deviations that occur during a period you identify as a startup, shutdown...

40 CFR 62.14645 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 9 2013-07-01 2013-07-01 false What happens during periods of startup... Limits § 62.14645 What happens during periods of startup, shutdown, and malfunction? (a) The emission limitations and operating limits apply at all times except during periods of CISWI unit startup, shutdown, or...

40 CFR 62.14645 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 8 2010-07-01 2010-07-01 false What happens during periods of startup... Limits § 62.14645 What happens during periods of startup, shutdown, and malfunction? (a) The emission limitations and operating limits apply at all times except during periods of CISWI unit startup, shutdown, or...

40 CFR 63.8248 - What other requirements must I meet?

Code of Federal Regulations, 2014 CFR

2014-07-01

... startup, shutdown, and malfunction. (2) You must report each instance in which you did not meet each work practice standard in § 63.8192 that applies to you. This includes periods of startup, shutdown, and... value was out of range. (b) Startups, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63...

40 CFR 62.14645 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 9 2012-07-01 2012-07-01 false What happens during periods of startup... Limits § 62.14645 What happens during periods of startup, shutdown, and malfunction? (a) The emission limitations and operating limits apply at all times except during periods of CISWI unit startup, shutdown, or...

40 CFR 62.14645 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 9 2014-07-01 2014-07-01 false What happens during periods of startup... Limits § 62.14645 What happens during periods of startup, shutdown, and malfunction? (a) The emission limitations and operating limits apply at all times except during periods of CISWI unit startup, shutdown, or...

40 CFR Table 14 to Subpart Wwww of... - Requirements for Reports

Code of Federal Regulations, 2013 CFR

2013-07-01

... requirements in § 63.5910(b). c. The information in § 63.10(d)(5)(i) if you had a startup, shutdown or malfunction during the reporting period, and you took actions consistent with your startup, shutdown, and malfunction plan Semiannually according to the requirements in § 63.5910(b). 2. An immediate startup, shutdown...

40 CFR 60.5180 - Do the emission limits, emission standards, and operating limits apply during periods of startup...

Code of Federal Regulations, 2011 CFR

2011-07-01

... standards, and operating limits apply during periods of startup, shutdown, and malfunction? 60.5180 Section... startup, shutdown, and malfunction? The emission limits and standards apply at all times and during... concentration limit using CO CEMS, the correction to 7 percent oxygen does not apply during periods of startup...

40 CFR Table 14 to Subpart Wwww of... - Requirements for Reports

Code of Federal Regulations, 2012 CFR

2012-07-01

... requirements in § 63.5910(b). c. The information in § 63.10(d)(5)(i) if you had a startup, shutdown or malfunction during the reporting period, and you took actions consistent with your startup, shutdown, and malfunction plan Semiannually according to the requirements in § 63.5910(b). 2. An immediate startup, shutdown...

40 CFR 60.5180 - Do the emission limits, emission standards, and operating limits apply during periods of startup...

Code of Federal Regulations, 2014 CFR

2014-07-01

... standards, and operating limits apply during periods of startup, shutdown, and malfunction? 60.5180 Section... startup, shutdown, and malfunction? The emission limits and standards apply at all times and during... concentration limit using CO CEMS, the correction to 7 percent oxygen does not apply during periods of startup...

40 CFR 62.14645 - What happens during periods of startup, shutdown, and malfunction?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 8 2011-07-01 2011-07-01 false What happens during periods of startup... Limits § 62.14645 What happens during periods of startup, shutdown, and malfunction? (a) The emission limitations and operating limits apply at all times except during periods of CISWI unit startup, shutdown, or...

40 CFR 60.5180 - Do the emission limits, emission standards, and operating limits apply during periods of startup...

Code of Federal Regulations, 2013 CFR

2013-07-01

... standards, and operating limits apply during periods of startup, shutdown, and malfunction? 60.5180 Section... startup, shutdown, and malfunction? The emission limits and standards apply at all times and during... concentration limit using CO CEMS, the correction to 7 percent oxygen does not apply during periods of startup...

40 CFR 60.5180 - Do the emission limits, emission standards, and operating limits apply during periods of startup...

Code of Federal Regulations, 2012 CFR

2012-07-01

... standards, and operating limits apply during periods of startup, shutdown, and malfunction? 60.5180 Section... startup, shutdown, and malfunction? The emission limits and standards apply at all times and during... concentration limit using CO CEMS, the correction to 7 percent oxygen does not apply during periods of startup...

40 CFR 63.8248 - What other requirements must I meet?

Code of Federal Regulations, 2012 CFR

2012-07-01

... meet each emission limitation in § 63.8190 that applies to you. This includes periods of startup... standard in § 63.8192 that applies to you. This includes periods of startup, shutdown, and malfunction. (3... range. (b) Startups, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63.7(e)(1...

40 CFR Table 14 to Subpart Wwww of... - Requirements for Reports

Code of Federal Regulations, 2014 CFR

2014-07-01

... requirements in § 63.5910(b). c. The information in § 63.10(d)(5)(i) if you had a startup, shutdown or malfunction during the reporting period, and you took actions consistent with your startup, shutdown, and malfunction plan Semiannually according to the requirements in § 63.5910(b). 2. An immediate startup, shutdown...

40 CFR 63.5555 - How do I demonstrate continuous compliance with the emission limits, operating limits, and work...

Code of Federal Regulations, 2012 CFR

2012-07-01

... periods of startup, shutdown, and malfunction. These instances are deviations from the emission limits...), deviations that occur during a period of startup, shutdown, or malfunction are not violations if you... Administrator will determine whether deviations that occur during a period you identify as a startup, shutdown...

Investigation of human biomarkers in exhaled breath by laser photoacoustic spectroscopy

NASA Astrophysics Data System (ADS)

Dumitras, D. C.; Giubileo, G.; Puiu, A.

2005-06-01

The paper underlines the importance of breath tests in medicine and the potential of laser techniques to measure in-vivo and in real time human biomarkers. The presence of trace amounts of gases or the metabolites of a precursor in exhaled air could be linked to kidney or liver malfunction, asthma, diabetes, cancer, ulcers or neurological disorders. The measurement of some human biomarkers (ethylene, ammonia), based on laser photoacoustic spectroscopy methods, insure very high sensitivity and selectivity. The technical characteristics of this instrument were measured to determine the detection limits (sub-ppb for ethylene). The results of ethylene release following lipid peroxidation initiated by X-ray irradiation or ingestion of radioactive compounds are presented. The possibility to extend this technique for measurement of breath ammonia levels in patients with end-stage renal disease while they are undergoing hemodialysis is discussed.

Gemini Program Mission Report for Gemini-Titan 1 (GT-1)

NASA Technical Reports Server (NTRS)

1964-01-01

The Gemini-Titan 1 (GT-1) space vehicle was comprised of the Gemini spacecraft and the Gemini launch vehicle. The Gemini launch vehicle is a two-stage modified Titan II ICBM. The major modifications are the addition of a malfunction detection system and a secondary flight controls system. The Gemini spacecraft, designed to carry a crew of two men on earth orbital and rendezvous missions, was unmanned for the flight reported herein (GT-1). There were no complete Gemini flight systems on board; however, the C-band transponder and telemetry transmitters were Gemini flight subsystems. Dummy equipment, having a mass and moment of inertia equal to flight system equipment, was installed in the spacecraft. The Spacecraft was instrumented to obtain data on spacecraft heating, structural loading, vibration, sound pressure levels, and temperature and pressure during the launch phase.

Stone-age mass spectrometry: the beginnings of "SIMS" at RCA Laboratories, Princeton

NASA Astrophysics Data System (ADS)

Honig, Richard E.

1995-05-01

This paper takes you back almost half a century, to the time when mass spectrometry was young and exciting, and research was exploring new frontiers every day. Our early experiments called "sputtering of surfaces by positive ion beams", now known as "SIMS", were carried out with the simple, yet flexible instrumentation available at that time and produced many interesting results that are still valid today. Since commercial equipment did not exist in those days, just about everything had to be designed and constructed in-house - hardware as well as circuitry. Thus progress was slow, but occasional malfunctioning of a component could be readily rectified. It is gratifying to see how SIMS has developed in the interim from our early feasibility studies into a major research effort carried out worldwide in many laboratories.

New Challenges in Tribology: Wear Assessment Using 3D Optical Scanners

PubMed Central

Valigi, Maria Cristina; Logozzo, Silvia; Affatato, Saverio

2017-01-01

Wear is a significant mechanical and clinical problem. To acquire further knowledge on the tribological phenomena that involve freeform mechanical components or medical prostheses, wear tests are performed on biomedical and industrial materials in order to solve or reduce failures or malfunctions due to material loss. Scientific and technological advances in the field of optical scanning allow the application of innovative devices for wear measurements, leading to improvements that were unimaginable until a few years ago. It is therefore important to develop techniques, based on new instrumentations, for more accurate and reproducible measurements of wear. The aim of this work is to discuss the use of innovative 3D optical scanners and an experimental procedure to detect and evaluate wear, comparing this technique with other wear evaluation methods for industrial components and biomedical devices. PMID:28772905

New Challenges in Tribology: Wear Assessment Using 3D Optical Scanners.

PubMed

Valigi, Maria Cristina; Logozzo, Silvia; Affatato, Saverio

2017-05-18

Wear is a significant mechanical and clinical problem. To acquire further knowledge on the tribological phenomena that involve freeform mechanical components or medical prostheses, wear tests are performed on biomedical and industrial materials in order to solve or reduce failures or malfunctions due to material loss. Scientific and technological advances in the field of optical scanning allow the application of innovative devices for wear measurements, leading to improvements that were unimaginable until a few years ago. It is therefore important to develop techniques, based on new instrumentations, for more accurate and reproducible measurements of wear. The aim of this work is to discuss the use of innovative 3D optical scanners and an experimental procedure to detect and evaluate wear, comparing this technique with other wear evaluation methods for industrial components and biomedical devices.

Noninvasive Thermal Evaluation of Ventriculoperitoneal Shunt Patency and Cerebrospinal Fluid Flow Using a Flow Enhancing Device.

PubMed

Hameed, Mustafa Q; Zurakowski, David; Proctor, Mark R; Stone, Scellig S D; Warf, Benjamin C; Smith, Edward R; Goumnerova, Liliana C; Swoboda, Marek; Anor, Tomer; Madsen, Joseph R

2018-06-16

While a noninvasive flow determination would be desirable in the diagnosis of cerebrospinal fluid shunt malfunction, existing studies have not yet defined a role for thermal flow detection. To evaluate a revised test protocol using a micropumper designed to transiently enhance flow during thermal testing to determine whether thermal detection of flow is associated with progression to shunt revision surgery. Eighty-two unique tests were performed in 71 shunts. The primary outcome, need for revision within 7 d of testing, was compared with results of micropumper-augmented thermal flow detection. Statistical analysis was based on blind interpretation of test results and raw temperature data recorded during testing. The test was sensitive (73%) and specific (68%) in predicting need for revision, with 5.6-fold higher probability of revision when flow was not detected. Negative predictive value in our sample was 94.2%. The probability of not requiring revision increased with increasing total temperature drop. Analysis of various possible thresholds showed that the optimal temperature cutoff may be lower than suggested by the manufacturer (0.125°C vs 0.2°C). This is the first study to report a strong association between thermal flow evaluation and a clinical impression that a shunt is not malfunctioning. The current recommended threshold may increase the false positive rate unnecessarily, and as clinicians gain experience with the method, they may find value in examining the temperature curves themselves. Multicenter studies are suggested to further define a role for this diagnostic test.

The VLTI Roadmap

NASA Astrophysics Data System (ADS)

Mérand, A.

2018-03-01

ESO's Very Large Telescope Interferometer (VLTI) was a unique facility when it was conceived more than 30 years ago, and it remains competitive today in the field of milli-arcsecond angular resolution astronomy. Over the past decade, while the VLTI matured into an operationally efficient facility, it became limited by its first-generation instruments. As the second generation of VLTI instrumentation achieves first light, further developments for this unique facility are being planned and are described here.

Endoscopic Third Ventriculostomy Instead of Shunt Revision in Children Younger Than 3 Years of Age.

PubMed

Zhao, Rui; Shi, Wei; Yang, Haowei; Li, Hao

2016-04-01

Endoscopic third ventriculostomy (ETV) is a valuable option in the treatment of shunt failure, but no clinical data exist for young children. The aim of this study was to elucidate the role of ETV in patients younger than 3 years of age with shunt malfunction. A cohort of 37 patients younger than 3 years of age with shunt malfunction underwent ETV instead of shunt revision. Patients' preoperative condition and medical history were studied to determine the impact of a number of variables on outcome. The Fisher exact test was used to assess differences among groups. Median age at ETV was 21.6 months (8-36 months). Diagnosis was obstructive hydrocephalus in 24 patients and communicating hydrocephalus in 13. Median age at initial shunt placement was 3.2 months (10 days to 30 months). The etiology of shunt malfunction was obstruction (n = 27) or infection (n = 10). Overall ETV failure rate was 40.5% (15/37). Patients whose age at initial shunt placement was <6 months and/or who had a preterm birth history had higher relative rates of ETV failure. Other variables, including type of hydrocephalus, interval between initial shunt placement and ETV, history of intraventricular bleeding and/or infection, and etiology of shunt malfunction, did not significantly affect the final outcome. Patients younger than 3 years with obstructive or communicating hydrocephalus may benefit from ETV in the event of shunt malfunction and have about a 60% probability of becoming shunt free. Copyright © 2016 Elsevier Inc. All rights reserved.

Radiotherapy and risk of implantable cardioverter-defibrillator malfunctions: experimental data from direct exposure at increasing doses.

PubMed

Zecchin, Massimo; Artico, Jessica; Morea, Gaetano; Severgnini, Mara; Bianco, Elisabetta; De Luca, Antonio; Fantasia, Anna Zorzin; Salvatore, Luca; Milan, Vittorino; Lucarelli, Matteo; Dissegna, Roberta; Cannatà, Antonio; Sinagra, Gianfranco

2018-04-01

During radiotherapy, in patients with implantable cardioverter-defibrillators (ICDs) malfunctions are considered more likely if doses more than 2 Gy reach the ICD site; however, most malfunctions occur with high-energy (>10 MV) radiations, and the risk is less defined using 6-MV linear accelerators. The purpose of the study is to experimentally evaluate the occurrence of malfunctions in ICDs radiated with a 6-MV linear accelerator at increasing photon doses. Thirty-two ICDs from all manufacturers (31 explanted and one demo) were evaluated; all devices with a sufficient battery charge underwent multiple radiations with a 6-MV photon beam reaching a cumulative dose at ICD site of 0.5, 1, 2, 3, 5 and 10 Gy and interrogated after every session. All antitachycardia therapies were left enabled; two ICDs were connected to a rhythm simulator (one simulating a complete atrioventricular block without ventricular activity) and visually monitored by external ECG and the ICD programmer during radiation. Thirteen ICDs were excluded before radiation because of battery depletion; after radiation up to the cumulative dose at the cardiac implantable electronic device site of 10 Gy, in the remaining 19 devices, programmation and battery charge remained unchanged and no switch to safety mode was observed; oversensing, pacing inhibition or inappropriate antitachycardia therapy were neither recorded nor visually observed during radiation. With a low-energy accelerator, neither malfunctions nor electromagnetic interferences were detected radiating the ICDs at doses usually reaching the ICD pocket during radiotherapy sessions. In this context, magnet application to avoid oversensing and inappropriate therapy seems, therefore, useless.

Comparison of two new generation pulse oximeters during emergency ambulance transportation.

PubMed

Weber, Ulrike; Tomschik, Elvira; Resch, Irene; Adelmann, Krista; Hasun, Matthias; Mora, Bruno; Malzer, Reinhard; Kober, Alexander

2011-02-01

We wanted to test whether there is a difference between the total number and duration of malfunctions and a correlation between the oxygen saturation and pulse rate values of two new generation pulse oximeters (Masimo 'Radical 7' and Nellcor 'N 600') during emergency ambulance transportation. Patients were monitored with two pulse oximeters ('Radical 7' and 'N 600') on different randomly selected fingers of the same hand during transportation. Data of both devices were recorded continuously by a laptop computer. Fifty-two patients with signs of peripheral vasoconstriction (including 22 patients with a blood pressure ≤100/60) were included. There were 0.21 ± 0.72 (0-4) malfunctions per patient lasting for a mean 113.55 ± 272.55 s in the 'Radical 7' and 0.13 ± 0.49 (0-3) malfunctions per patient with a mean duration of 301.0 ± 426.58 s in the 'N 600'. Oxygen saturation and pulse rate values correlated significantly [r² = 0.9608 (SpO₂), r² = 0.9608 (pulse rate)] between the devices and showed a bias of -0.177770 (SpO₂) and 0.310883 (pulse rate) with a standard deviation of 1.68367 (SpO₂) and 4.46532 (pulse rate) in a Bland-Altman test. Although number and duration of malfunctions did not differ significantly between the devices, they showed a very low number of malfunctions even in hypotensive patients with peripheral vasoconstriction. Oxygen saturation correlated significantly in the two devices investigated at 49.409 time points. In addition, pulse rate also correlated significantly.

PubMed Central

Vanasse, A.; Courteau, J.

2001-01-01

OBJECTIVE: To assess the precision and integrity of all aneroid and mercury sphygmomanometers regularly used by family physicians practising outside hospitals. DESIGN: Cross-sectional study. SETTING: Private medical clinics and local community health centres in Bas-Saint-Laurent, Qué. PARTICIPANTS: A total of 151 of the 166 physicians in this administrative region. MAIN OUTCOME MEASURES: Precision of the mercury sphygmomanometers was measured using the difference between a reading in the absence of pressure and level 0. Precision of the aneroid sphygmomanometers was measured using variations at pressures of 140 mm Hg and 90 mm Hg compared with those on a calibrated mercury sphygmomanometer. Integrity of sphygmomanometers, arm cuffs, and inflating bulbs was also assessed. RESULTS: In all, 258 sphygmomanometers met the inclusion criteria (111 mercury sphygmomanometers and 147 aneroid sphygmomanometers). Discrepancies of > or = 4 mm Hg were found in 15.5% of these instruments (12.6% and 17.7% of the mercury and aneroid sphygmomanometers, respectively). In 31.0% of the instruments (52.3% and 15.0% of the mercury and aneroid sphygmomanometers, respectively), one component was malfunctioning. CONCLUSION: Sphygmomanometers that measure patients' blood pressure inaccurately could result in an incorrect diagnosis of hypertension or in a normal blood pressure reading in a hypertensive patient. PMID:11228028

Recognizing and Reducing Analytical Errors and Sources of Variation in Clinical Pathology Data in Safety Assessment Studies.

PubMed

Schultze, A E; Irizarry, A R

2017-02-01

Veterinary clinical pathologists are well positioned via education and training to assist in investigations of unexpected results or increased variation in clinical pathology data. Errors in testing and unexpected variability in clinical pathology data are sometimes referred to as "laboratory errors." These alterations may occur in the preanalytical, analytical, or postanalytical phases of studies. Most of the errors or variability in clinical pathology data occur in the preanalytical or postanalytical phases. True analytical errors occur within the laboratory and are usually the result of operator or instrument error. Analytical errors are often ≤10% of all errors in diagnostic testing, and the frequency of these types of errors has decreased in the last decade. Analytical errors and increased data variability may result from instrument malfunctions, inability to follow proper procedures, undetected failures in quality control, sample misidentification, and/or test interference. This article (1) illustrates several different types of analytical errors and situations within laboratories that may result in increased variability in data, (2) provides recommendations regarding prevention of testing errors and techniques to control variation, and (3) provides a list of references that describe and advise how to deal with increased data variability.

Involvement of the Anterior Segment of the Eye in Patients with Mucopolysaccharidoses: A Review of Reported Cases and Updates on the Latest Diagnostic Instrumentation.

PubMed

Bruscolini, A; Amorelli, G M; Rama, P; Lambiase, A; La Cava, M; Abbouda, A

2017-01-01

Mucopolysaccharidoses (MPS) are a heterogeneous group of rare inherited disorders, characterized by the lack or malfunction of lysosomal enzymes necessary for glycosaminoglycan (GAGs) catabolism, and their subsequent accumulation in many tissues and organs throughout the body. An overview of the current knowledge of corneal and anterior segment manifestations in patients with MPS was provided and clinical guidelines for their diagnosis and management were furnished. The anterior segment of the eye is usually involved in every subtype of MPS, with major complications including varying degrees of corneal opacification and raised intraocular pressure (IOP) with development of glaucoma. Their recognition and management can be very useful in the diagnosis of MPS. Novel techniques are available to objectively measure the grade and extent of corneal clouding and give information about the anatomy of the anterior chamber and the structures of the angle beyond the clouded cornea. It is advisable to take advantage of this new instrumentation in order to obtain thorough information on the ocular involvement and its related anterior chamber complications for a better management of patients with MPS, both in terms of visual prognosis and therapeutic outcome.

76 FR 7238 - Pipeline Safety: Dangers of Abnormal Snow and Ice Build-Up on Gas Distribution Systems

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-09

... been related to either the stress of snow and ice or the malfunction of pressure control equipment due... to have been related to either the stress of snow and ice or malfunction of pressure control... from the stresses imposed by the additional loading of the snow or ice. Damage to facilities may also...

Air Force Female Pilots Program: Initial Performance and Attitudes

DTIC Science & Technology

1979-02-01

you conduct most of your training? a. Controlled (Control Tower) b. FSS (Airport Advisory Service) c. Unicorn d. Uncontrolled (No Unicom or FSS) 9...Travel_____ b. Business c, Employment _____ d. Sport_____ e. Education_____ f. Other (Specify) ____________________ 26...Ceiling 6. High Winds 3. Turbulence 7. Mud or Snow 4. Airframe Icing 8. Darkness d. Equipment Failure 1. Engine Operations 3. Malfunction(s): Equipment

40 CFR 60.4861 - How do I establish an affirmative defense for exceedance of an emission limit or standard during...

Code of Federal Regulations, 2014 CFR

2014-07-01

... affirmative defense to a claim for civil penalties for exceedances of emission limits that are caused by..., using best monitoring methods and engineering judgment, the amount of excess emissions that were the... malfunction, if it wishes to avail itself of an affirmative defense to civil penalties for that malfunction...

40 CFR 60.4861 - How do I establish an affirmative defense for exceedance of an emission limit or standard during...

Code of Federal Regulations, 2013 CFR

2013-07-01

... affirmative defense to a claim for civil penalties for exceedances of emission limits that are caused by..., using best monitoring methods and engineering judgment, the amount of excess emissions that were the... malfunction, if it wishes to avail itself of an affirmative defense to civil penalties for that malfunction...

75 FR 54462 - Airworthiness Directives; Bombardier-Rotax GmbH 912 F Series and 912 S Series Reciprocating Engines

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-08

... Airworthiness Directives; Bombardier-Rotax GmbH 912 F Series and 912 S Series Reciprocating Engines AGENCY... result in exceeding of the fuel pressure and might cause engine malfunction and/or massive fuel leakage... engine malfunction or a massive fuel leak. These conditions could cause loss of control of the airplane...

40 CFR 63.7746 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2012 CFR

2012-07-01

... periods of startup, shutdown, and malfunction. You also must report each instance in which you did not... according to the requirements of § 63.7751. (b) Startups, shutdowns, and malfunctions. (1) Consistent with the requirements of §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup...

40 CFR 63.8691 - How do I demonstrate continuous compliance with the operating limits?

Code of Federal Regulations, 2014 CFR

2014-07-01

... operating limit in Table 5 to this subpart that applies to you. This includes periods of startup, shutdown... §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup, shutdown, or malfunction... of startup, shutdown, or malfunction are violations, according to the provisions in § 63.6(e). [68 FR...

40 CFR 63.7746 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2010 CFR

2010-07-01

... periods of startup, shutdown, and malfunction. You also must report each instance in which you did not... according to the requirements of § 63.7751. (b) Startups, shutdowns, and malfunctions. (1) Consistent with the requirements of §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup...

40 CFR 63.7746 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2013 CFR

2013-07-01

... periods of startup, shutdown, and malfunction. You also must report each instance in which you did not... according to the requirements of § 63.7751. (b) Startups, shutdowns, and malfunctions. (1) Consistent with the requirements of §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup...

40 CFR 63.7336 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2010 CFR

2010-07-01

... periods of startup, shutdown, and malfunction. You must also report each instance in which you did not... must be reported according to the requirements in § 63.7341. (b) Startup, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup...

40 CFR 63.8691 - How do I demonstrate continuous compliance with the operating limits?

Code of Federal Regulations, 2010 CFR

2010-07-01

... operating limit in Table 5 to this subpart that applies to you. This includes periods of startup, shutdown... §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup, shutdown, or malfunction... of startup, shutdown, or malfunction are violations, according to the provisions in § 63.6(e). [68 FR...

40 CFR 63.7336 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2013 CFR

2013-07-01

... periods of startup, shutdown, and malfunction. You must also report each instance in which you did not... must be reported according to the requirements in § 63.7341. (b) Startup, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup...

40 CFR 63.8691 - How do I demonstrate continuous compliance with the operating limits?

Code of Federal Regulations, 2011 CFR

2011-07-01

... operating limit in Table 5 to this subpart that applies to you. This includes periods of startup, shutdown... §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup, shutdown, or malfunction... of startup, shutdown, or malfunction are violations, according to the provisions in § 63.6(e). [68 FR...

40 CFR 63.7746 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2011 CFR

2011-07-01

... periods of startup, shutdown, and malfunction. You also must report each instance in which you did not... according to the requirements of § 63.7751. (b) Startups, shutdowns, and malfunctions. (1) Consistent with the requirements of §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup...

40 CFR 63.7336 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2014 CFR

2014-07-01

... periods of startup, shutdown, and malfunction. You must also report each instance in which you did not... must be reported according to the requirements in § 63.7341. (b) Startup, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup...

40 CFR 63.7746 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2014 CFR

2014-07-01

... periods of startup, shutdown, and malfunction. You also must report each instance in which you did not... according to the requirements of § 63.7751. (b) Startups, shutdowns, and malfunctions. (1) Consistent with the requirements of §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup...

40 CFR 63.7336 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2011 CFR

2011-07-01

... periods of startup, shutdown, and malfunction. You must also report each instance in which you did not... must be reported according to the requirements in § 63.7341. (b) Startup, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup...

40 CFR 63.8691 - How do I demonstrate continuous compliance with the operating limits?

Code of Federal Regulations, 2012 CFR

2012-07-01

... operating limit in Table 5 to this subpart that applies to you. This includes periods of startup, shutdown... §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup, shutdown, or malfunction... of startup, shutdown, or malfunction are violations, according to the provisions in § 63.6(e). [68 FR...

40 CFR 63.7336 - What other requirements must I meet to demonstrate continuous compliance?

Code of Federal Regulations, 2012 CFR

2012-07-01

... periods of startup, shutdown, and malfunction. You must also report each instance in which you did not... must be reported according to the requirements in § 63.7341. (b) Startup, shutdowns, and malfunctions. (1) Consistent with §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup...

40 CFR 63.8691 - How do I demonstrate continuous compliance with the operating limits?

Code of Federal Regulations, 2013 CFR

2013-07-01

... operating limit in Table 5 to this subpart that applies to you. This includes periods of startup, shutdown... §§ 63.6(e) and 63.7(e)(1), deviations that occur during a period of startup, shutdown, or malfunction... of startup, shutdown, or malfunction are violations, according to the provisions in § 63.6(e). [68 FR...

40 CFR Table 2 to Subpart Tttt of... - Leather Finishing HAP Emission Limits for Determining the Allowable HAP Loss

Code of Federal Regulations, 2012 CFR

2012-07-01

...)(ii)(H) Application for approval Type and quantity of HAP, operating parameters No All sources emit... listed below. § 63.6(e)(3) Operation and maintenance requirements Startup, shutdown, and malfunction plan requirements No Subpart TTTT does not have any startup, shutdown, and malfunction plan requirements. § 63.6(f...

40 CFR Table 2 to Subpart Tttt of... - Leather Finishing HAP Emission Limits for Determining the Allowable HAP Loss

Code of Federal Regulations, 2014 CFR

2014-07-01

...)(ii)(H) Application for approval Type and quantity of HAP, operating parameters No All sources emit... listed below. § 63.6(e)(3) Operation and maintenance requirements Startup, shutdown, and malfunction plan requirements No Subpart TTTT does not have any startup, shutdown, and malfunction plan requirements. § 63.6(f...

40 CFR Table 2 to Subpart Tttt of... - Leather Finishing HAP Emission Limits for Determining the Allowable HAP Loss

Code of Federal Regulations, 2013 CFR

2013-07-01

...)(ii)(H) Application for approval Type and quantity of HAP, operating parameters No All sources emit... listed below. § 63.6(e)(3) Operation and maintenance requirements Startup, shutdown, and malfunction plan requirements No Subpart TTTT does not have any startup, shutdown, and malfunction plan requirements. § 63.6(f...

Hearing Aid Tester

NASA Technical Reports Server (NTRS)

1978-01-01

Hearing aids often develop malfunctions that are not detected by the wearer. This is particularly true when the wearers are school-age children. Studies of selected groups showed that from 30 to more than 50 percent of school children were not getting adequate benefit from their hearing aids because of unrecognized malfunctions, usually low or dead batteries. This can be serious because hearing impairment retards a child's educational progress. NASA technology incorporated in the Hearing Aid Malfunction Detection Unit (HAMDU), the device pictured, is expected to provide an effective countermeasure to the childrens' hearing aid problem. A patent license has been awarded to a minority-owned firm, Hopkins International Company, a subsidiary of H. H. Aerospace Design Co., Inc., Elmford, New York. The company plans early commercial availability of its version of the device.

Cassini Ion Mass Spectrometer Peak Calibrations from Statistical Analysis of Flight Data

NASA Astrophysics Data System (ADS)

Woodson, A. K.; Johnson, R. E.

2017-12-01

The Cassini Ion Mass Spectrometer (IMS) is an actuating time-of-flight (TOF) instrument capable of resolving ion mass, energy, and trajectory over a field of view that captures nearly the entire sky. One of three instruments composing the Cassini Plasma Spectrometer, IMS sampled plasma throughout the Kronian magnetosphere from 2004 through 2012 when it was permanently disabled due to an electrical malfunction. Initial calibration of the flight instrument at Southwest Research Institute (SwRI) was limited to a handful of ions and energies due to time constraints, with only about 30% of planned measurements carried out prior to launch. Further calibration measurements were subsequently carried out after launch at SwRI and Goddard Space Flight Center using the instrument prototype and engineering model, respectively. However, logistical differences among the three calibration efforts raise doubts as to how accurately the post-launch calibrations describe the behavior of the flight instrument. Indeed, derived peak parameters for some ion species differ significantly from one calibration to the next. In this study we instead perform a statistical analysis on 8 years of flight data in order to extract ion peak parameters that depend only on the response of the flight instrument itself. This is accomplished by first sorting the TOF spectra based on their apparent compositional similarities (e.g. primarily water group ions, primarily hydrocarbon ions, etc.) and normalizing each spectrum. The sorted, normalized data are then binned according to TOF, energy, and counts in order to generate energy-dependent probability density maps of each ion peak contour. Finally, by using these density maps to constrain a stochastic peak fitting algorithm we extract confidence intervals for the model parameters associated with various measured ion peaks, establishing a logistics-independent calibration of the body of IMS data gathered over the course of the Cassini mission.

76 FR 20953 - Application(s) for Duty-Free Entry of Scientific Instruments

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-14

...., 9700 South Cass Ave., Lemont, IL 60439. Instrument: Mythen 1K Detector System. Manufacturer: Dectris... (RIXS) to study the electronic structure of highly correlated systems. This instrument is unique in that... dynamic range; and a small, lightweight and compact design. Justification for Duty-Free Entry: There are...

Early Childhood Assessment: Recommended Practices and Selected Instruments.

ERIC Educational Resources Information Center

Smith, Steven Lynn, Ed.; Rundall, Dick, Ed.

This manual, developed from an Early Childhood Institute on the Assessment of Young Children conducted in 1981, acquaints education and counseling professionals with a variety of assessment instruments for young handicapped children and assists them in understanding how to adapt instruments to a child's unique disability. Information to facilitate…

Spacecraft utility and the development of confidence intervals for criticality of anomalies

NASA Technical Reports Server (NTRS)

Williams, R. E.

1980-01-01

The concept of spacecraft utility, a measure of its performance in orbit, is discussed and its formulation is described. Performance is defined in terms of the malfunctions that occur and the criticality to the mission of these malfunctions. Different approaches to establishing average or expected values of criticality are discussed and confidence intervals are developed for parameters used in the computation of utility.

40 CFR Table 2 to Subpart Tttt of... - Leather Finishing HAP Emission Limits for Determining the Allowable HAP Loss

Code of Federal Regulations, 2010 CFR

2010-07-01

... paragraphs of § 63.5 as listed below. § 63.5(c) [Reserved] § 63.5(d)(1)(ii)(H) Application for approval Type... maintenance requirements Startup, shutdown, and malfunction plan requirements No Subpart TTTT does not have any startup, shutdown, and malfunction plan requirements. § 63.6(f)-(g) Compliance with nonopacity...

40 CFR Table 2 to Subpart Tttt of... - Leather Finishing HAP Emission Limits for Determining the Allowable HAP Loss

Code of Federal Regulations, 2011 CFR

2011-07-01

... paragraphs of § 63.5 as listed below. § 63.5(c) [Reserved] § 63.5(d)(1)(ii)(H) Application for approval Type... maintenance requirements Startup, shutdown, and malfunction plan requirements No Subpart TTTT does not have any startup, shutdown, and malfunction plan requirements. § 63.6(f)-(g) Compliance with nonopacity...

VESUVIO: a novel instrument for performing spectroscopic studies in condensed matter with eV neutrons at the ISIS facility

NASA Astrophysics Data System (ADS)

Senesi, R.; Andreani, C.; Bowden, Z.; Colognesi, D.; Degiorgi, E.; Fielding, A. L.; Mayers, J.; Nardone, M.; Norris, J.; Praitano, M.; Rhodes, N. J.; Stirling, W. G.; Tomkinson, J.; Uden, C.

2000-03-01

The VESUVIO project aims to provide unique prototype instrumentation at the ISIS-pulsed neutron source and to establish a routine experimental and theoretical program in neutron scattering spectroscopy at eV energies. This instrumentation will be specifically designed for high momentum, (20 Å-11 eV) inelastic neutron scattering studies of microscopic dynamical processes in materials and will represent a unique facility for EU researchers. It will allow to derive single-particle kinetic energies and single-particle momentum distributions, n(p), providing additional and/or complementary information to other neutron inelastic spectroscopic techniques.

Procedural Tests for Anti-G Protective Devices. Volume II. G-Sensitivity Tests

DTIC Science & Technology

1979-12-01

of these valves was used in only one type of aircraft--the ALAR AGV in ...pattern. 3) Total included, inexplicitly in the total for this column along with Failures au.d OTH/MAL’s are Type 6 HOW MALFUNCTION CODES--which...maintenance. Because Type 6 HOW MALFUNCTION CODESI. .were not considered pertinent to this investigation, they wer!. not included in the report. All figures of

75 FR 67949 - Application(s) for Duty-Free Entry of Scientific Instruments

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-04

... University of Texas at Austin, Center for Electromechanics, Pickle Research Campus 10100 Burnet Road, Bldg...., Italy. Intended Use: The instrument will be used on the Hobby-Eberly Telescope for the study of ``Dark Energy.'' The instrument is unique because of its ability to achieve the desired accuracy of +/- 2...

Online Course Design in Higher Education: A Review of National and Statewide Evaluation Instruments

ERIC Educational Resources Information Center

Baldwin, Sally; Ching, Yu-Hui; Hsu, Yu-Chang

2018-01-01

This research identifies six online course evaluation instruments used nationally or in statewide systems. We examined the characteristics (i.e., number of standards and criteria) and coded the criteria that guide the design of online courses. We discussed the focus of the instruments and their unique features.

Instrumental motives in negative emotion regulation in daily life: Frequency, consistency, and predictors.

PubMed

Kalokerinos, Elise K; Tamir, Maya; Kuppens, Peter

2017-06-01

People regulate their emotions not only for hedonic reasons but also for instrumental reasons, to attain the potential benefits of emotions beyond pleasure and pain. However, such instrumental motives have rarely been examined outside the laboratory as they naturally unfold in daily life. To assess whether and how instrumental motives operate outside the laboratory, it is necessary to examine them in response to real and personally relevant stimuli in ecologically valid contexts. In this research, we assessed the frequency, consistency, and predictors of instrumental motives in negative emotion regulation in daily life. Participants (N = 114) recalled the most negative event of their day each evening for 7 days and reported their instrumental motives and negative emotion goals in that event. Participants endorsed performance motives in approximately 1 in 3 events and social, eudaimonic, and epistemic motives in approximately 1 in 10 events. Instrumental motives had substantially higher within- than between-person variance, indicating that they were context-dependent. Indeed, although we found few associations between instrumental motives and personality traits, relationships between instrumental motives and contextual variables were more extensive. Performance, social, and epistemic motives were each predicted by a unique pattern of contextual appraisals. Our data demonstrate that instrumental motives play a role in daily negative emotion regulation as people encounter situations that pose unique regulatory demands. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Comparing Data from Telescopic X-Ray Instruments: Can We Trust All Satellites?

NASA Astrophysics Data System (ADS)

Joyce, Quianah T.; Fortenberry, Alexander; Gendre, Bruce

2017-01-01

In astronomy and astrophysics, X-ray emissions from cosmic entities aid in revealing what type of sources they emanate from. Swift, NASA’s latest X-ray satellite, has not been operating at its intended configurations. The satellite is experiencing difficulties maintaining a stable temperature in its charge capture device. This research intends to determine if this complication causes discrepancies in Swift’s collected data by using gamma-ray burst data. Gamma-ray bursts are excellent comparison candidates due to their brightness and fluctuations. We compared archived data of GRB 130427A and GRB 090423A from Swift and the European Space Agency’s XMM-Newton observatory. Next, we reduced the data and produced the respective spectra. We then analyzed and compared the spectra to one another to find any discrepancies. We have determined, based on data analysis of the spectra, that Swift is working properly despite the cooling malfunction.

Experimental apparatus to test air trap valves

NASA Astrophysics Data System (ADS)

Lemos De Lucca, Y. de F.; de Aquino, G. A.; Filho, J. G. D.

2010-08-01

It is known that the presence of trapped air within water distribution pipes can lead to irregular operation or even damage to the distribution systems and their components. The presence of trapped air may occur while the pipes are being filled with water, or while the pumping systems are in operation. The formation of large air pockets can produce the water hammer phenomenon, the instability and the loss of pressure in the water distribution networks. As a result, it can overload the pumps, increase the consumption of electricity, and damage the pumping system. In order to avoid its formation, all of the trapped air should be removed through "air trap valves". In Brazil, manufacturers frequently have unreliable sizing charts, which cause malfunctioning of the "air trap valves". The result of these malfunctions causes accidents of substantial damage. The construction of a test facility will provide a foundation of technical information that will be used to help make decisions when designing a system of pipelines where "air trap valves" are used. To achieve this, all of the valve characteristics (geometric, mechanic, hydraulic and dynamic) should be determined. This paper aims to describe and analyze the experimental apparatus and test procedure to be used to test "air trap valves". The experimental apparatus and test facility will be located at the University of Campinas, Brazil at the College of Civil Engineering, Architecture, and Urbanism in the Hydraulics and Fluid Mechanics laboratory. The experimental apparatus will be comprised of various components (pumps, steel pipes, butterfly valves to control the discharge, flow meter and reservoirs) and instrumentation (pressure transducers, anemometer and proximity sensor). It should be emphasized that all theoretical and experimental procedures should be defined while taking into consideration flow parameters and fluid properties that influence the tests.

Thermal monitoring, measurement, and control system for a Volatile Condensable Materials (VCM) test apparatus

NASA Technical Reports Server (NTRS)

Ives, R. E.

1982-01-01

A thermal monitoring and control concept is described for a volatile condensable materials (VCM) test apparatus where electric resistance heaters are employed. The technique is computer based, but requires only proportioning ON/OFF relay control signals supplied through a programmable scanner and simple quadrac power controllers. System uniqueness is derived from automatic temperature measurements and the averaging of these measurements in discrete overlapping temperature zones. Overall control tolerance proves to be better than + or - 0.5 C from room ambient temperature to 150 C. Using precisely calibrated thermocouples, the method provides excellent temperature control of a small copper VCM heating plate at 125 + or - 0.2 C over a 24 hr test period. For purposes of unattended operation, the programmable computer/controller provides a continual data printout of system operation. Real time operator command is also provided for, as is automatic shutdown of the system and operator alarm in the event of malfunction.

Natural and technologic hazardous material releases during and after natural disasters: a review.

PubMed

Young, Stacy; Balluz, Lina; Malilay, Josephine

2004-04-25

Natural disasters may be powerful and prominent mechanisms of direct and indirect hazardous material (hazmat) releases. Hazardous materials that are released as the result of a technologic malfunction precipitated by a natural event are referred to as natural-technologic or na-tech events. Na-tech events pose unique environmental and human hazards. Disaster-associated hazardous material releases are of concern, given increases in population density and accelerating industrial development in areas subject to natural disasters. These trends increase the probability of catastrophic future disasters and the potential for mass human exposure to hazardous materials released during disasters. This systematic review summarizes direct and indirect disaster-associated releases, as well as environmental contamination and adverse human health effects that have resulted from natural disaster-related hazmat incidents. Thorough examination of historic disaster-related hazmat releases can be used to identify future threats and improve mitigation and prevention efforts.

Development of Thin-Film Battery Powered Transdermal Medical Devices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bates, J.B.; Sein, T.

1999-07-06

Research carried out at ORNL has led to the development of solid state thin-film rechargeable lithium and lithium-ion batteries. These unique devices can be fabricated in a variety of shapes and to any required size, large or small, on virtually any type of substrate. Because they have high energies per unit of volume and mass and because they are rechargeable, thin-film lithium batteries have potentially many applications as small power supplies in consumer and special electronic products. Initially, the objective of this project was to develop thin-film battery powered products. Initially, the objective of this project was to develop thin-filmmore » battery powered transdermal electrodes for recording electrocardiograms and electroencephalograms. These ''active'' electrode would eliminate the effect of interference and improve the reliability in diagnosing heart or brain malfunctions. Work in the second phase of this project was directed at the development of thin-film battery powered implantable defibrillators.« less

Mass Spectrometry for Planetary Probes: Past, Present and Future

NASA Technical Reports Server (NTRS)

Niemann, Hasso B.; Harpold, Dan N.; Jamieson, Brian G.; Mahaffy, Paul R.

2005-01-01

Atmospheric entry probes present a unique opportunity for performing quantitative analysis of extra-terrestrial atmospheres in cases where remote sensing alone may not be sufficient and measurements with balloons or aircraft is not practical. An entry probe can provide a complete vertical profile of atmospheric parameters including chemical composition, which cannot be obtained with most other techniques. There are, however, unique challenges associated with building instruments for an entry probe, as compared to orbiters, landers, or rovers. Conditions during atmospheric entry are extreme, there are inherent time constraints due to the short duration of the experiment, and the instrument experiences rapid environmental changes in temperature and pressure as it descends. In addition, there are resource limitations, i.e. mass, power, size and bandwidth. Finally, the demands on the instrument design are determined in large part by conditions (pressure, temperature, composition) unique to the particular body under study, and as a result there is no one-size-fits-all instrument for an atmospheric probe. Many of these requirements can be more easily met by miniaturizing the probe instrument. Our experience building mass spectrometers for atmospheric entry probes leads us to believe that the time is right for a fundamental change in the way spaceflight mass spectrometers are built. The emergence over the past twenty years of Micro-electro- mechanical Systems (MEMS), utilizing lithographic semiconductor fabrication techniques to produce instrument systems in miniature, holds great promise for application to spaceflight mass spectrometry. A highly miniaturized, high performance and low-power mass spectrometer would be an enormous benefit to future entry probe missions, allowing, for example, parallel measurements (e.g., multiple simultaneous gas chromatographic analyses and direct atmospheric leaks.) Such an instrument would also enable mass spectrometry on board small multiple entry probes. In the development of a MEMS Mass Spectrometer, the challenge facing us is to move beyond the proof-of-concept, where research dollars tend to focus, and carry out the detailed work of developing a high performance mass spectrometer system on a chip which meets the unique technical requirements for an atmospheric entry probe described above.

Preventable wheelchair-related thermal injury.

PubMed

Bull, William; Priebe, Michael; Dillig, Gina; Dado, Diane

2006-01-01

Wheelchair-related injuries are common, and with proper reporting of injuries, advanced technologic support may offer new ways to prevent those injuries. Case REPORT AND FINDINGS: A man with tetraplegia who retains only minimal use of his right hand experienced a right-sided armrest malfunction of his wheelchair resulting in his wheelchair controls being out of reach. This left him stranded in the sun for almost 2 hours in 86 degrees F weather. During that time, he developed full thickness sunburns of his left forearm and deep partial thickness burns of the left fingertips where they were in contact with the left armrest. This patient's full thickness burns could have been prevented if his motorized wheelchair had back-up communication in the event of a malfunction. Technology developers must realize the need for such systems. Health care professionals must advocate for a higher standard of safety and report injuries related to wheelchair malfunction.

Facial trauma caused by electronic cigarette explosion.

PubMed

Vaught, Brian; Spellman, Joseph; Shah, Anil; Stewart, Alexander; Mullin, David

2017-03-01

Electronic cigarettes are increasingly popular as a supposed safer alternative to tobacco cigarettes or a smoking cessation tool. Research and debate have focused primarily on possible adverse effects caused by the inhaled aerosol produced by electronic cigarettes and on smoking cessation efficacy. Few reports in the medical literature describe injuries secondary to device malfunction. We present a case of electronic cigarette explosion, with a projectile fracturing the patient's right naso-orbital-ethmoid complex and anterior and posterior frontal sinus tables, with frontal sinus outflow tract involvement. The patient underwent combined open and endoscopic repair, including open reduction internal fixation, with reconstitution and preservation of the frontal sinus and frontal sinus outflow tract. Additionally, we review the available data on electronic cigarette malfunction-including fires, explosions, associated injuries, and possible reasons for device malfunction-and discuss new 2016 U.S. Food and Drug Administration regulations pertaining to electronic cigarettes.

75 FR 3895 - Application(s) for Duty-Free Entry of Scientific Instruments

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-25

... instrument must be able to perform using lasers with both continuous wave (CW) and pulsed mode. The use of picoseconds pulsed lasers is necessary to measure fluorescence lifetime. The use of CW lasers, so that the... controls the laser head provides user-selectable pulsed repetition rates. This instrument is unique in that...

Jonathan W. Amy and the Amy Facility for Instrumentation Development.

PubMed

Cooks, R Graham

2017-05-16

This Perspective describes the unique Jonathan Amy Facility for Chemical Instrumentation in the Department of Chemistry at Purdue University, tracing its history and mode of operation. It also describes aspects of the career of its namesake and some of his insights which have been central to analytical instrumentation development, improvement, and utilization, both at Purdue and nationally.

Development of a generic system for real-time data access and remote control of multiple in-situ water quality monitoring instruments

NASA Astrophysics Data System (ADS)

Wright, S. A.; Bennett, G. E.; Andrews, T.; Melis, T. S.; Topping, D. J.

2005-05-01

Currently, in-situ monitoring of water quality parameters (e.g. water temperature, conductivity, turbidity) in the Colorado River ecosystem typically consists of deploying instruments in the river, retrieving them at a later date, downloading the datalogger, then examining the data; an arduous process in the remote settings of Grand Canyon. Under this protocol, data is not available real-time and there is no way to detect problems with the instrumentation until after retrieval. The next obvious stage in the development of in-situ monitoring in Grand Canyon was the advent of one-way telemetry, i.e. streaming data in real-time from the instrument to the office and/or the world-wide-web. This protocol allows for real-time access to data and the identification of instrumentation problems, but still requires a site visit to address instrument malfunctions, i.e. the user does not have the ability to remotely control the instrument. At some field sites, such as the Colorado River in Grand Canyon, site visitation is restricted by remoteness and lack of traditional access routes (i.e. roads). Even at less remote sites, it may still be desirable to have two-way communication with instruments in order to, for example, diagnose and potentially fix instrumentation problems, change sampling parameters to save battery power, etc., without having to visit the site. To this end, the U.S. Geological Survey, Grand Canyon Monitoring and Research Center, is currently developing and testing a high-speed, two-way communication system that allows for real-time data access and remote control of instrumentation. The approach tested relies on internet access and may be especially useful in areas where land-line or cellular connections are unavailable. The system is composed of off-the-shelf products, uses a commercial broadband satellite service, and is designed in a generic way such that any instrument that communicates through RS-232 communication (i.e. a serial port) is compatible with the system. We are currently testing the system at two sites on the Colorado River in Grand Canyon and at one critical monitoring site on the Paria River where we have deployed suites of instruments for monitoring flow, sediment concentration, temperature, and conductivity. One aspect of the system that may be particularly useful for ecohydrological applications is the ability to remotely control on-site pump samplers, which allows for the collection of a water sample by the press of a button in the office.

Fentanyl overdose caused by malfunction of SynchroMed II intrathecal pump: two case reports.

PubMed

Maino, Paolo; Koetsier, Eva; Perez, Roberto S G M

2014-01-01

Intrathecal drug delivery systems (intrathecal pumps) are used to treat patients with chronic refractory pain syndromes and spasticity. The objective of our case report was to demonstrate that intrathecal pump malfunction can lead to intrathecal overdosing of drugs. We present 2 cases of intrathecal pump malfunction leading to overinfusion. The first case concerns a patient with an intrathecal pump that was implanted almost 5 years before the reported incident. During a refill procedure, 12.5 mL was aspirated instead of the expected 21.8 mL. Analysis of the pump revealed that the pump was overinfusing. The second case concerns a patient with an intrathecal pump that was implanted more than 5 years before the reported incident. Ten hours after a regular refill of the pump, she was found in a comatose state, and when the intrathecal pump was emptied, only 16 mL was aspirated instead of the 19.6 mL expected. Analysis of the pump revealed that the inner tubing was not running smoothly over the roller arms, possibly causing spurts, which could have caused an overinfusion. We present 2 cases of intrathecal pump malfunction, which most likely led to overinfusion of fentanyl intrathecally. To reduce the risk of this complication, particular attention should be paid to drug reservoir volume discrepancies and overdose symptoms reported by patients.

Measuring Environmental Factors: Unique and Overlapping International Classification of Functioning, Disability and Health Coverage of 5 Instruments.

PubMed

Heinemann, Allen W; Miskovic, Ana; Semik, Patrick; Wong, Alex; Dashner, Jessica; Baum, Carolyn; Magasi, Susan; Hammel, Joy; Tulsky, David S; Garcia, Sofia F; Jerousek, Sara; Lai, Jin-Shei; Carlozzi, Noelle E; Gray, David B

2016-12-01

To describe the unique and overlapping content of the newly developed Environmental Factors Item Banks (EFIB) and 7 legacy environmental factor instruments, and to evaluate the EFIB's construct validity by examining associations with legacy instruments. Cross-sectional, observational cohort. Community. A sample of community-dwelling adults with stroke, spinal cord injury, and traumatic brain injury (N=568). None. EFIB covering domains of the built and natural environment; systems, services, and policies; social environment; and access to information and technology; the Craig Hospital Inventory of Environmental Factors (CHIEF) short form; the Facilitators and Barriers Survey/Mobility (FABS/M) short form; the Home and Community Environment Instrument (HACE); the Measure of the Quality of the Environment (MQE) short form; and 3 of the Patient Reported Outcomes Measurement Information System's (PROMIS) Quality of Social Support measures. The EFIB and legacy instruments assess most of the International Classification of Functioning, Disability and Health (ICF) environmental factors chapters, including chapter 1 (products and technology; 75 items corresponding to 11 codes), chapter 2 (natural environment and human-made changes; 31 items corresponding to 7 codes), chapter 3 (support and relationships; 74 items corresponding to 7 codes), chapter 4 (attitudes; 83 items corresponding to 8 codes), and chapter 5 (services, systems, and policies; 72 items corresponding to 16 codes). Construct validity is provided by moderate correlations between EFIB measures and the CHIEF, MQE barriers, HACE technology mobility, FABS/M community built features, and PROMIS item banks and by small correlations with other legacy instruments. Only 5 of the 66 legacy instrument correlation coefficients are moderate, suggesting they measure unique aspects of the environment, whereas all intra-EFIB correlations were at least moderate. The EFIB measures provide a brief and focused assessment of ICF environmental factor chapters. The pattern of correlations with legacy instruments provides initial evidence of construct validity. Copyright © 2016 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

Including Non-Traditional Instrumentation in Undergraduate Environmental Chemistry Courses

ERIC Educational Resources Information Center

Jenkins, J. David; Orvis, Jessica N.; Smith, C. Jimmy; Manley, Citabria; Rice, Jeanette K. 2

2004-01-01

Non-traditional instrumentation was obtained for Georgia Southern undergraduates to attain fundamental environmental education through unique laboratory experiences. In this context, the method for including a direct mercury analyzer into both major and non-major environmental laboratories is reported.

48 CFR 4.1601 - Policy.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Policy. 4.1601 Section 4... MATTERS Unique Procurement Instrument Identifiers 4.1601 Policy. (a) Procurement Instrument Identifier... regulations, applicable authorities, and agency policies and procedures. (e) Agencies shall not change the...

48 CFR 4.1601 - Policy.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Policy. 4.1601 Section 4... MATTERS Unique Procurement Instrument Identifiers 4.1601 Policy. (a) Procurement Instrument Identifier... regulations, applicable authorities, and agency policies and procedures. (e) Agencies shall not change the...

77 FR 76457 - Howard Hughes Medical Institute, et al.; Notice of Consolidated Decision on Applications for Duty...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-28

... chemical state and their catalytic activity in various chemical reactions, by investigating solid... instrument. The unique features of this instrument include its small volume (0.045 L) reaction cell in which...

The Five-String Banjo in the Music Classroom

ERIC Educational Resources Information Center

Smith, Kenneth H.

2011-01-01

The banjo is an instrument of unique image and sound. It has a long history in North America from its arrival on slave ships from North Africa to its contemporary use in jazz and popular music. Adding the instrument to the general music classroom can open new realms of timbre and new avenues of exploration into the instruments of cultures around…

The Future of Carbon Monoxide Measurements from Space

NASA Astrophysics Data System (ADS)

Drummond, J.

It is now over 20 years since the Measurements of Air Pollution from Space MAPS instrument made the first measurements of tropospheric carbon monoxide from the shuttle Since that time a number of instruments have flown including the Measurements Of Pollution In The Troposphere MOPITT Tropospheric Emission Spectrometer TES and SCanning Imaging Absorption SpectroMeter for Atmospheric CHartographY SCIAMCHY to name only three of many Each of these instruments has a unique observing method and unique mission characteristics It is accepted that measurements of carbon monoxide provide a useful proxy of the pollution of the troposphere and contribute significantly to studies of various phenomena in the atmosphere and atmosphere-surface interactions These measurements should therefore be continued -- but in what form Technology has progresses significantly since the current generation of instruments was designed and our ability to interpret the data from such instrumentation has likewise expanded It is therefore fruitful to consider what is the best set of measurements that can be made which parameters should be emphasized and which compromised on the way to the next generation of sensors The Measurements of Air Pollution Levels in the Environment MAPLE instrument is a study financed by the Canadian Space Agency to design a next-generation instrument and since instrument spacecraft and mission are now intimately linked a consideration of the whole mission is appropriate This talk will outline some potential developments in the hardware

Hydraulophones: Acoustic musical instruments and expressive user interfaces

NASA Astrophysics Data System (ADS)

Janzen, Ryan E.

Fluid flow creates an expansive range of acoustic possibilities, particularly in the case of water, which has unique turbulence and vortex shedding properties as compared with the air of ordinary wind instruments. Sound from water flow is explained with reference to a new class of musical instruments, hydraulophones, in which oscillation originates directly from matter in its liquid state. Several hydraulophones which were realized in practical form are described. A unique user-interface consisting of a row of water jets is presented, in terms of its expressiveness, tactility, responsiveness to derivatives and integrals of displacement, and in terms of the direct physical interaction between a user and the physical process of sound production. Signal processing algorithms are introduced, which extract further information from turbulent water flow, for industrial applications as well as musical applications.

The OTELO Project

NASA Astrophysics Data System (ADS)

Cepa, J.; Alfaro, E. J.; Castañeda, H. O.; Gallego, J.; González-Serrano, J. I.; González, J. J.; Jones, D. H.; Pérez-García, A. M.; Sánchez-Portal, M.

2007-06-01

OSIRIS is the Spanish Day One instrument for the GTC 10.4-m telescope. OSIRIS is a general purpose instrument for imaging, low-resolution long slit and multi-object spectroscopy (MOS). OSIRIS has a field of view of 8.6×8.6 arcminutes, which makes it ideal for deep surveys, and operates in the optical wavelength range from 365 through 1000nm. The main characteristic that makes OSIRIS unique amongst other instruments in 8-10m class telescopes is the use of Tunable Filters (Bland-Hawthorn & Jones 1998). These allow a continuous selection of both the central wavelength and the width, thus providing scanning narrow band imaging within the OSIRIS wavelength range. The combination of the large GTC aperture, large OSIRIS field of view and availability of the TFs makes OTELO a truly unique emission line survey.

The use of heteroduplex analysis of polymerase chain reaction products to support the possible transmission of Legionella pneumophila from a malfunctioning automobile air conditioner.

PubMed

Pinar, Ahmet; Ramirez, Julio A; Schindler, Laura L; Miller, Richard D; Summersgill, James T

2002-03-01

Air conditioner condensates have not been previously associated with cases of Legionnaires' disease. We report the possible transmission of Legionella pneumophila serogroup 1 from a malfunctioning automobile air conditioning system's leaking water onto the floorboard of a car driven for a long distance by the patient. Heteroduplex analysis of polymerase chain reaction products was used to help establish an epidemiologic link between the water specimen and the patient.

Parent/guardian knowledge regarding implanted shunt type, setting, and symptoms of malfunction/infection.

PubMed

Ackerman, Laurie L; Fulkerson, Daniel H; Jea, Andrew; Smith, Jodi L

2018-04-01

OBJECTIVE Patients with shunts often interact with providers distant from their primary hospital, making it important that the parent(s)/guardian(s) is well versed in the type of shunt implanted and symptoms of malfunction/infection. This is particularly important with magnetic-sensitive programmable valves, as the use of MRI becomes more prevalent. METHODS Over a 6-month period, primary caregivers of 148 consecutive patients who received shunts were prospectively administered questionnaires at clinic visits. Caregivers were asked to do the following: 1) identify shunt valve name, type, and setting if applicable; 2) list symptoms of shunt malfunction/infection; and 3) indicate whether they had access to references regarding shunt type/setting, booklets from the Hydrocephalus Association, and quick reference cards with symptoms of shunt malfunction/infection. One cohort of caregivers (n = 75) was asked to carry informational cards with shunt valve/setting information (group I); this cohort was compared with another subgroup of caregivers (n = 73) not carrying cards (group II). RESULTS The mean (± SD) age of patients at implantation/revision was 3.71 ± 4.91 years, and the age at follow-up was 6.12 ± 5.4 years. The average time from surgery to administration of the questionnaire was 2.38 ± 3.22 years. There were 86 new shunt insertions and 62 revisions. One hundred twenty-eight caregivers (87%) could identify the type of valve (programmable vs nonprogrammable). On the other hand, only 72 caregivers (49%) could identify the valve name. Fifty-four of 73 (74%) caregivers of patients who had shunts with programmable valves could correctly identify the valve setting. One hundred caregivers (68%) had a copy of the Hydrocephalus Association booklet, and 103 (70%) had quick reference cards. Eighty caregivers (54%) had references on shunt type/setting. Most caregivers (127 [86%]) could name ≥ 3 signs/symptoms of shunt malfunction, with vomiting (61%), headache (49%), and sleeps more/lethargic (35%) most frequently reported. Caregivers of patients in group I were more likely to have cards with symptoms of shunt infection or malfunction (p = 0.015); have information cards regarding shunt type/setting (p < 0.001); and correctly identify valve type (p = 0.001), name (p < 0.001), and setting if programmable (p = 0.0016). There were no differences in ability to list symptoms of shunt malfunction or infection (p = 0.8812) or in access to Hydrocephalus Association booklets (p = 0.1288). There were no significant demographic differences between the groups, except that group I patients had a shorter time from surgery to last follow-up (1.66 vs 3.17 years; p = 0.0001). CONCLUSIONS Education regarding the care of patients with shunts by providing written cards with shunt type/setting and access to reference materials seems to be effective. Developing plans for guided instruction with assessment in the clinic setting of a caregiver's knowledge is important for patient safety.

U.S. Geological Survey

NASA Technical Reports Server (NTRS)

1996-01-01

The Hydrologic Instrumentation Facility (HIF) at Stennis Space Center is a unique high-tech facility that provides hydrologic instrumentation support to the U. S. Geological Survey and other federal agencies worldwide. The HIF has the responsibility for warehousing, testing, evaluating, designing, repairing, and calibrating numerous pieces of hydrologic instrumentation, which is used in studying water on the surface, in the soil, and in the atmosphere of the Earth.

The James Webb Space Telescope Integrated Science Instrument Module

NASA Technical Reports Server (NTRS)

Greenhouse, Matthew A.; Sullivan, Pamela C.; Boyce, Leslye A.; Glazer, Stuart D.; Johnson, Eric L.; McCloskey, John C.; Voyton, Mark F.

2004-01-01

The Integrated Science Instrument Module of the James Webb Space Telescope is described from a systems perspective with emphasis on unique and advanced technology aspects. The major subsystems of this flight element are described including: structure, thermal, command and data handling, and software.

Potential commercial uses of EOS remote sensing products

NASA Technical Reports Server (NTRS)

Thompson, Leslie L.

1991-01-01

The instrument complement of the Earth Observing System (EOS) satellite system will generate data sets with potential interest to a variety of users who are now just beginning to develop geographic information systems tailored to their special applications and/or jurisdictions. Other users may be looking for a unique product that enhances competitive position. The generally distributed products from EOS will require additional value added processing to derive the unique products desired by specific users. Entrepreneurs have an opportunity to create these proprietary level 4 products from the EOS data sets. Specific instruments or collections of instruments could provide information for crop futures trading, mineral exploration, television and printed medium news products, regional and local government land management and planning, digital map directories, products for third world users, ocean fishing fleet probability of harvest forecasts, and other areas not even imagined at this time. The projected level 3 product are examined that will be available at launch from EOS instruments and commercial uses of the data after value added processing is estimated.

The photons payload, G-494: A learning experience

NASA Technical Reports Server (NTRS)

Harris, F. R.; Gattinger, R. L.; Creutzberg, F.; Llewellyn, E. J.

1988-01-01

PHOTONS (Photometric Thermospheric Oxygen Nightglow Study) is an optical remote sensing payload developed for Get Away Special (GAS) flight by the National Research Council of Canada. The device is extremely sensitive and is suitable for making measurements of low intensity, aeronomically generated atmospheric emissions in the nadir and the limb and of Shuttle ram glow. The unit uses a sealed canister and UV transmitting viewing ports. During the flight of STS 61-C, PHOTONS received one hour of operation and aeronomic observations were made. Good diagnostic data were obtained and the science part of the experiment malfunctioned. Post flight inspection revealed that the payload was in perfect working order except for total failure of the photomultiplier detectors. The experiment and the payload are described and the flight results are discussed along with the cause of the malfunctions. It is shown that enough was learned from the flight diagnostic data and about the cause of the malfunction to conclude that the engineering flight was successful and that subsequent flight of the PHOTONS payload will be productive.

Power train and emission control: allocation procedure by OBD-II system for automotive technology

NASA Astrophysics Data System (ADS)

Kalita, Porag

2017-06-01

OBD-II, systems were designed to maintain low emissions of in use vehicles, including light and medium duty vehicles. In 1989, the California code of Regulations (CCR) known as OBD - II was adopted by the California Air Resource Board (CARB) and the objective to reduce hydrocarbon (HC) emission caused by malfunction of the vehicles emission control systems. OBD-II provides additional information to engineer for diagnosis and repair of emissions related problems. OBD-II, standardizes on the amount of memory (Freeze Frame) it uses to store the readings of the vehicle sensor when it logs on emission related Intermittent Trouble code (IT). The intent of OBD-II, systems is to detect most vehicle malfunctions when performance of a power train component or system deteriorates to the point that the vehicle’s HC emission exceed standard. The vehicle operator is notified at the time when the vehicle begins to marginally exceed emission standards, by illuminating the Malfunctions Indicator Light (MIL).

A.I.-based real-time support for high performance aircraft operations

NASA Technical Reports Server (NTRS)

Vidal, J. J.

1985-01-01

Artificial intelligence (AI) based software and hardware concepts are applied to the handling system malfunctions during flight tests. A representation of malfunction procedure logic using Boolean normal forms are presented. The representation facilitates the automation of malfunction procedures and provides easy testing for the embedded rules. It also forms a potential basis for a parallel implementation in logic hardware. The extraction of logic control rules, from dynamic simulation and their adaptive revision after partial failure are examined. It uses a simplified 2-dimensional aircraft model with a controller that adaptively extracts control rules for directional thrust that satisfies a navigational goal without exceeding pre-established position and velocity limits. Failure recovery (rule adjusting) is examined after partial actuator failure. While this experiment was performed with primitive aircraft and mission models, it illustrates an important paradigm and provided complexity extrapolations for the proposed extraction of expertise from simulation, as discussed. The use of relaxation and inexact reasoning in expert systems was also investigated.