Opening the Doors of Opportunity: Liberal Education and the Veterans

ERIC Educational Resources Information Center

Gaines, Francis P.

2004-01-01

Since the GI Bill radically changed U.S. higher education, the question arose as to whether (then) American Association of Colleges, AAC was involved in the planning and implementation of the GI Bill that brought service men and women to college and university campuses. The answer is that the Association was deeply involved, if one looks at the…

Heading South on 'Erebus Highway'

NASA Technical Reports Server (NTRS)

2005-01-01

NASA's Mars Exploration Rover Opportunity is currently traveling southward over a pavement of outcrop dubbed the 'Erebus Highway.' 'Erebus Crater,' the rover's next target, lies less than 100 meters (328 feet) south of its current position. This view is a mosaic produced from from frames taken by the rover's navigation camera during Opportunity's 582nd martian day, or sol (Sept. 13, 2005). It shows fractured blocks of ancient sedimentary rock separated by recent sand dunes. Mars Exploration Rover team scientists are investigating both the composition of the rocks and the processes by which the distinctive fracture pattern arose.

Lifelong Learning: The Value of an Industrial Internship for a Graduate Student Education

ERIC Educational Resources Information Center

Honda, Gregory S.; Pazmino, Jorge H.; Hickman, Daniel A.; Varma, Arvind

2015-01-01

A chemical engineering PhD student from Purdue University completed an internship at The Dow Chemical Company, evaluating the effect of scale on the hydrodynamics of a trickle bed reactor. A unique aspect of this work was that it arose from an ongoing collaboration, so that the project was within the scope of the graduate student's thesis. This…

Northwest Territories Protected Areas Strategy: How community values are shaping the protection of wild spaces and heritage places

Treesearch

Angela Stadel; Raymond Taniton; Heidi Heder

2002-01-01

The Northwest Territories Protected Areas Strategy (NWT PAS), approved in 1999, presents a unique community-driven approach to establishing a network of protected areas in the North. The NWT PAS arose from increasing resource development pressures in the Northwest Territories and is being implemented in the context of the land claim and treaty processes. Aboriginal...

Does the Curriculum Matter in Peer Mentoring? From Mentee to Mentor in Problem-Based Learning: A Unique Case Study

ERIC Educational Resources Information Center

McLean, Michelle

2004-01-01

Peer mentoring has been used for many years by the Nelson R. Mandela School of Medicine to integrate new students into the academic and social culture of the institution. In 2001, an unusual situation arose. A problem-based learning (PBL) curriculum was introduced and the first cohort in this programme was mentored by senior traditional curriculum…

Well construction information, lithologic logs, water level data, and overview of research in Handcart Gulch, Colorado: an alpine watershed affected by metalliferous hydrothermal alteration

USGS Publications Warehouse

Caine, Jonathan S.; Manning, Andrew H.; Verplanck, Philip L.; Bove, Dana J.; Kahn, Katherine Gurley; Ge, Shemin

2006-01-01

Integrated, multidisciplinary studies of the Handcart Gulch alpine watershed provide a unique opportunity to study and characterize the geology and hydrology of an alpine watershed along the Continental Divide. The study area arose out of the donation of four abandoned, deep mineral exploration boreholes to the U.S. Geological Survey for research purposes by Mineral Systems Inc. These holes were supplemented with nine additional shallow holes drilled by the U.S. Geological Survey along the Handcart Gulch trunk stream. All of the holes were converted into observation wells, and a variety of data and samples were measured and collected from each. This open-file report contains: (1) An overview of the research conducted to date in Handcart Gulch; (2) well location, construction, lithologic log, and water level data from the research boreholes; and (3) a brief synopsis of preliminary results. The primary purpose of this report is to provide a research overview as well as raw data from the boreholes. Interpretation of the data will be reported in future publications. The drill hole data were tabulated into a spreadsheet included with this digital open-file report.

Teaching English as a Foreign Language to Students with Learning Disabilities at the Intermediate and Advanced Levels: A Multiple-Strategies Approach

ERIC Educational Resources Information Center

El-Koumy, Abdel Salam A.

2016-01-01

The idea of this book arose out of an awareness that students with language learning disabilities are completely ignored in the Egyptian school system and there are no special programs that cater to these students. They are placed in normal schools that are not prepared to deal with their unique difficulties. This book, therefore, is an attempt to…

Explaining human uniqueness: genome interactions with environment, behaviour and culture.

PubMed

Varki, Ajit; Geschwind, Daniel H; Eichler, Evan E

2008-10-01

What makes us human? Specialists in each discipline respond through the lens of their own expertise. In fact, 'anthropogeny' (explaining the origin of humans) requires a transdisciplinary approach that eschews such barriers. Here we take a genomic and genetic perspective towards molecular variation, explore systems analysis of gene expression and discuss an organ-systems approach. Rejecting any 'genes versus environment' dichotomy, we then consider genome interactions with environment, behaviour and culture, finally speculating that aspects of human uniqueness arose because of a primate evolutionary trend towards increasing and irreversible dependence on learned behaviours and culture - perhaps relaxing allowable thresholds for large-scale genomic diversity.

Explaining human uniqueness: genome interactions with environment, behaviour and culture

PubMed Central

Varki, Ajit; Geschwind, Daniel H.; Eichler, Evan E.

2009-01-01

What makes us human? Specialists in each discipline respond through the lens of their own expertise. In fact, ‘anthropogeny’ (explaining the origin of humans) requires a transdisciplinary approach that eschews such barriers. Here we take a genomic and genetic perspective towards molecular variation, explore systems analysis of gene expression and discuss an organ-systems approach. Rejecting any ‘genes versus environment’ dichotomy, we then consider genome interactions with environment, behaviour and culture, finally speculating that aspects of human uniqueness arose because of a primate evolutionary trend towards increasing and irreversible dependence on learned behaviours and culture — perhaps relaxing allowable thresholds for large-scale genomic diversity. PMID:18802414

NATO Enlargement--Round Two; Prudence or Folly?

DTIC Science & Technology

1999-04-01

about the 60% level . See Golden, 28, and Binnendijk, 56. 34 This figure was based on results of a ground analysis performed by SHAPE which estimated... A Research Report Submitted to the Faculty In Partial Fulfillment of the Graduation Requirements Advisor: Lt Col Charles E. Costanzo Maxwell Air Force...foreign and defense policies, but could also have a very real and personal impact on me as an Air Force officer. As a result, when the opportunity arose

USSR Report, Military Affairs

DTIC Science & Technology

1986-01-10

Forces? ■ ;■„..:■’ [Kurkotkin] First, let" us define what we mean by the troops’ daily life [byt] today. Looking at it superficially, it is only a sphere...of problems. In some dis- tricts, groups of forces, and fleets too much attention was devoted to those garrisons which were represented in the...Any interval between fighting, if, of course, the opportunity arose, was used to give people a bath. Not for nothing did the poet Aleksandr

JPRS Report, East Asia, Southeast Asia, The Decisive Years: Memoirs of Vietnamese Senior General Hoang Van Thai

DTIC Science & Technology

1987-06-23

governmental system , in order to maintain and develop the forces of the revolution in the governmental administration and the mass organizations, build... operatinal modes in order to, in future years, form three strong fists (the rural areas, the urban areas, and the main-force units). When the strategic...opportunity arose, when the comparison of forces between ourselves and the enemy underwent a_ fundamental change, when the United States was

Minimally invasive surgery fellowship graduates: Their demographics, practice patterns, and contributions.

PubMed

Park, Adrian E; Sutton, Erica R H; Heniford, B Todd

2015-12-01

Fellowship opportunities in minimally invasive surgery, bariatric, gastrointestinal, and hepatobiliary arose to address unmet training needs. The large cohort of non-Accreditation Council for Graduate Medical Education -accredited fellowship graduates (NACGMEG) has been difficult to track. In this, the largest survey of graduates to date, our goal was to characterize this unique group's demographics and professional activities. A total of 580 NACGMEG were surveyed covering 150 data points: demographics, practice patterns, academics, lifestyle, leadership, and maintenance of certification. Of 580 previous fellows, 234 responded. Demographics included: average age 37 years, 84% male, 75% in urban settings, 49% in purely academic practice, and 58% in practice <5 years. They averaged 337 operating room cases/year (approximately 400/year for private practice vs 300/year for academic). NACGMEG averaged 100 flexible endoscopies/year (61 esophagogastroduodenoscopies, 39 colon). In the past 24 months, 60% had submitted abstracts to a national meeting, and 54% submitted manuscripts to peer-reviewed journals. Subset analyses revealed relevant relationships. There was high satisfaction (98%) that their fellowship experience met expectations; 78% termed their fellowships, versus 50% for residencies, highly pertinent to their current practices. 63% of previous fellows occupy local leadership roles, and most engage in maintenance of certification activities. Fellowship alumnae appear to be productive contributors to American surgery. They are clinically and academically active, believe endoscopy is important, have adopted continuous learning, and most assume work leadership roles. The majority acknowledge their fellowship training as having met expectations and uniquely equipping them for their current practice. Copyright © 2015 Elsevier Inc. All rights reserved.

The Contextuality Loophole is Fatal for the Derivation of Bell Inequalities: Reply to a Comment by I. Schmelzer

NASA Astrophysics Data System (ADS)

Nieuwenhuizen, Theodorus M.; Kupczynski, Marian

2017-02-01

Ilya Schmelzer wrote recently: Nieuwenhuizen argued that there exists some "contextuality loophole" in Bell's theorem. This claim in unjustified. It is made clear that this arose from attaching a meaning to the title and the content of the paper different from the one intended by Nieuwenhuizen. "Contextual loophole" means only that if the supplementary parameters describing measuring instruments are correctly introduced, Bell and Bell-type inequalities may not be proven. It is also stressed that a hidden variable model suffers from a "contextuality loophole" if it tries to describe different sets of incompatible experiments using a unique probability space and a unique joint probability distribution.

Cooperative Tertiary Interaction Network Guides RNA Folding

DOE Office of Scientific and Technical Information (OSTI.GOV)

Behrouzi, Reza; Roh, Joon Ho; Kilburn, Duncan

2013-04-08

Noncoding RNAs form unique 3D structures, which perform many regulatory functions. To understand how RNAs fold uniquely despite a small number of tertiary interaction motifs, we mutated the major tertiary interactions in a group I ribozyme by single-base substitutions. The resulting perturbations to the folding energy landscape were measured using SAXS, ribozyme activity, hydroxyl radical footprinting, and native PAGE. Double- and triple-mutant cycles show that most tertiary interactions have a small effect on the stability of the native state. Instead, the formation of core and peripheral structural motifs is cooperatively linked in near-native folding intermediates, and this cooperativity depends onmore » the native helix orientation. The emergence of a cooperative interaction network at an early stage of folding suppresses nonnative structures and guides the search for the native state. We suggest that cooperativity in noncoding RNAs arose from natural selection of architectures conducive to forming a unique, stable fold.« less

Conducting transcultural research: critical thinking in Thailand.

PubMed

Jenkins, Sheryl D

2011-01-01

Little has been written to help researchers prepare for the unique challenges of conducting transcultural research. The purpose of this article is to discuss issues that arose during the planning and execution of a transcultural study designed to compare critical thinking in Thailand and the United States. The challenges of identifying a research site, selecting participants, incorporating Thai research into the literature review, traveling and living in a foreign culture, overcoming cultural barriers to research, and strengthening internal validity and reliability are addressed.

Visualising the invisible

NASA Astrophysics Data System (ADS)

Laychak, M. B.

2008-06-01

In addition to the optical camera Megacam, the Canada-France-Hawaii Telescope operates a large field infrared camera, Wircam, and a spectrograph/spectropolimeter, Espadons. When these instruments were commissioned, the challenge arose to create educational outreach programmes incorporating the concepts of infrared astronomy and spectroscopy. We integrated spectroscopy into discussions of extrasolar planets and the search for life, two topics routinely requested by teachers for classroom talks. Making the infrared accessible to students provided a unique challenge, one that we met through the implementation and use of webcams modified for infrared use.

Attitudinal and motivational antecedents of participation in voluntary employee development activities.

PubMed

Hurtz, Gregory M; Williams, Kevin J

2009-05-01

This study investigated factors influencing ongoing participation in employee development activities. A multiple-indicator structural equation model building on the theory of planned behavior and prior employee development literature was tested with a survey across 4 organizations on 2 occasions. The model uses reactions to past participation and past supportiveness of the social and organizational environment as indirect antecedents of participation, filtered through their impact on attitudes and behavioral intentions toward future participation. Learning goal orientation also influenced attitudes toward participation. Whereas personal control over participation and higher levels of voluntariness were negatively related to participation, intentions to participate and availability of opportunities arose as strong predictors of higher participation rates. Many significant hypothesized paths were found, and 85% of the variance in participation was explained by the model variables. Increasing employee awareness of opportunities and managing positive attitudes toward those opportunities are recommended as key factors for increasing participation rates. (c) 2009 APA, all rights reserved.

Functional chloroplasts in metazoan cells - a unique evolutionary strategy in animal life

PubMed Central

2009-01-01

Background Among metazoans, retention of functional diet-derived chloroplasts (kleptoplasty) is known only from the sea slug taxon Sacoglossa (Gastropoda: Opisthobranchia). Intracellular maintenance of plastids in the slug's digestive epithelium has long attracted interest given its implications for understanding the evolution of endosymbiosis. However, photosynthetic ability varies widely among sacoglossans; some species have no plastid retention while others survive for months solely on photosynthesis. We present a molecular phylogenetic hypothesis for the Sacoglossa and a survey of kleptoplasty from representatives of all major clades. We sought to quantify variation in photosynthetic ability among lineages, identify phylogenetic origins of plastid retention, and assess whether kleptoplasty was a key character in the radiation of the Sacoglossa. Results Three levels of photosynthetic activity were detected: (1) no functional retention; (2) short-term retention lasting about one week; and (3) long-term retention for over a month. Phylogenetic analysis of one nuclear and two mitochondrial loci revealed reciprocal monophyly of the shelled Oxynoacea and shell-less Plakobranchacea, the latter comprising a monophyletic Plakobranchoidea and paraphyletic Limapontioidea. Only species in the Plakobranchoidea expressed short- or long-term kleptoplasty, most belonging to a speciose clade of slugs bearing parapodia (lateral flaps covering the dorsum). Bayesian ancestral character state reconstructions indicated that functional short-term retention arose once in the last common ancestor of Plakobranchoidea, and independently evolved into long-term retention in four derived species. Conclusion We propose a sequential progression from short- to long-term kleptoplasty, with different adaptations involved in each step. Short-term kleptoplasty likely arose as a deficiency in plastid digestion, yielding additional energy via the release of fixed carbon. Functional short-term retention was an apomorphy of the Plakobranchoidea, but the subsequent evolution of parapodia enabled slugs to protect kleptoplasts against high irradiance and further prolong plastid survival. We conclude that functional short-term retention was necessary but not sufficient for an adaptive radiation in the Plakobranchoidea, especially in the genus Elysia which comprises a third of all sacoglossan species. The adaptations necessary for long-term chloroplast survival arose independently in species feeding on different algal hosts, providing a valuable study system for examining the parallel evolution of this unique trophic strategy. PMID:19951407

Ion beam analysis in cultural heritage studies: Milestones and perspectives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dran, Jean-Claude; Calligaro, Thomas

2013-07-18

For three decades, ion beam analysis (IBA) in external mode was considered as the best choice for the characterisation of cultural heritage materials, as it combines excellent analytical performance and non-invasive character. However, in recent years, other analytical techniques arose as serious competitors, such as those based on synchrotron radiation (X-ray absorption, fluorescence or diffraction) or those using portable instruments (XRF, micro-Raman). It is shown that nevertheless IBA remains unmatched thanks to two unique features, namely the analysis of light elements and the high-resolution 3D chemical imaging.

Summary of the BIOMOVS A4 scenario: Testing models of the air-pasture-cow milk pathway using Chernobyl fallout data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peterson, S.R.; Hoffman, F.O.; Koehler, H.

1996-08-01

A unique opportunity to test dose assessment models arose after the Chernobyl reactor accident. During the passage of the contaminated plume, concentrations of {sup 131}I and {sup 137}Cs in air, pasture, and cow`s milk were collected at various sites in the northern hemisphere. Afterwards, contaminated pasture and milk samples were analyzed over time. Under the auspices of the Biospheric Model Validation Study (BIOMOVS), data from 13 sites for {sup 131}I and 10 sites for {sup 137}Cs were used to test model predictions for the air-pasture-cow milk pathway. Calculations were submitted for 23 models, 10 of which were quasi-steady state. Themore » others were time-dependent. Daily predictions and predictions of time-integrated concentration of {sup 131}I and {sup 137}Cs in pasture grass and milk for six months post-accident were calculated and compared with observed data. Testing against data from several locations over time for several steps in the air-to-milk pathway resulted in a better understanding of important processes and how they should be modeled. This model testing exercise showed both the strengths and weaknesses of the models and revealed the importance of testing all parts of dose assessment models whenever possible. 19 refs., 14 figs., 4 tabs.« less

Knowledge management practices in healthcare settings: a systematic review.

PubMed

Karamitri, Ioanna; Talias, Michael A; Bellali, Thalia

2017-01-01

Knowledge is an intangible asset in Organizations, and provides a comparative advantage to those who possess it. Hospitals are complex organizations with unique characteristics because of the heterogeneity of health professionals' orientation, the composite networking and the decision-making processes. A deeper understanding of knowledge management (KM) could streamline productivity and coordinate the use of resources more efficient. We conducted a systematic literature search of peer-reviewed papers that described key elements of KM using three databases (Medline, Cinahl and Health Source: nursing/academic edition) for a 10-year period (1/1/2004-25/11/2014). The included articles were subjected to qualitative content analysis. We retrieved 604 articles of which 20 articles were eligible for analysis. Most of the studies (n=13) used a qualitative methodology. The total sample size was 2155 participants. The key elements that arose were as follows: perceptions of KM, synthesis, dissemination, collaboration, means of KM and leadership. Moreover, this study identified barriers for KM implementation, like time restrictions and limited skills. Healthcare managers ought to cultivate a knowledge environment, operate as role models, provide the tools for KM and reward people who act as knowledge brokers. Opportunities for collaboration and knowledge sharing should be encouraged. Successful KM should be patient-centered to gain its maximum value. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.

Karl Schwarzschild Lecture: The Ups and Downs of the Hubble Constant (With 12 Figures)

NASA Astrophysics Data System (ADS)

Tammann, G. Andreas

2006-01-01

A brief history of the determination of the Hubble constant H_0 is given. Early attempts following Lemaitre (1927) gave much too high values due to errors of the magnitude scale, Malmquist bias and calibration problems. By 1962 most authors agreed that 75< H_0 <130. After 1975 a dichotomy arose with values near 100 and others around 55. The former came from apparent-magnitude-limited samples and were affected by Malmquist bias. New distance indicators were introduced; they were sometimes claimed to yield high values of H_0, but the most recent data lead to H_0 in the 60's, yet with remaining difficulties as to the zero-point of the respective distance indicators. SNe Ia with their large range and very small luminosity dispersion (avoiding Malmquist bias) offer a unique opportunity to determine the large-scale value of H_0. Their maximum luminosity can be well calibrated from 10 SNe Ia in local parent galaxies whose Cepheids have been observed with HST. An unforeseen difficulty - affecting all Cepheid distances - is that their P-L relation varies from galaxy to galaxy, presumably in function of metallicity. A proposed solution is summarized here. The conclusion is that H_0 = 63.2 +/- 1.3 (random) +/- 5.3 (systematic) on all scales. The expansion age becomes then (with Omega_m=0.3, Omega_Lambda=0.7) 15.1 Gyr.

The Stocker AstroScience Center at Florida International University

NASA Astrophysics Data System (ADS)

Webb, James R.

2014-01-01

The new Stocker AstroScience Center located on the MMC campus at Florida International University in Miami Florida represents a unique facility for STEM education that arose from a combination of private, State and university funding. The building, completed in the fall of 2013, contains some unique spaces designed not only to educate, but also to inspire students interested in science and space exploration. The observatory consists of a 4-story building (3 floors) with a 24” ACE automated telescope in an Ash dome, and an observing platform above surrounding buildings. Some of the unique features of the observatory include an entrance/exhibition hall with a 6-ft glass tile floor mural linking the Florida climate to space travel, a state-of-the art telescope control that looks like a starship bridge, and displays such as “Music from the universe”. The observatory will also be the focus of our extensive public outreach program that is entering its 20 year.

Studies of Solar Wind Interaction and Ionospheric Processes at Venus and Mars

NASA Technical Reports Server (NTRS)

Bogan, Denis (Technical Monitor); Nagy, Andrew F.

2003-01-01

This is the final report summarizing the work done during the last three years under NASA Grant NAG5-8946. Our efforts centered on a systematic development of a new generation of three dimensional magneto-hydrodynamic (MHD) numerical code, which models the interaction processes of the solar wind or fast flowing magnetospheric plasma with 'non-magnetic' solar system bodies (e.g. Venus, Mars, Europa, Titan). We have also worked on a number of different, more specific and discrete studies, as various opportunities arose. In the next few pages we briefly summarize these efforts.

The contributions of premating and postmating selection episodes to total selection in sex-role-reversed Gulf pipefish.

PubMed

Rose, Emily; Paczolt, Kimberly A; Jones, Adam G

2013-09-01

Empirical studies of sexual selection often focus on events occurring either before or after mating but rarely both and consequently may fail to discern the relative magnitudes and interactions of premating and postmating episodes of selection. Here, we simultaneously quantify premating and postmating selection in the sex-role-reversed Gulf pipefish by using a microsatellite-based analysis of parentage in experimental populations. Female pipefish exhibited an opportunity for selection (I) of 1.64, which was higher than that of males (0.35). Decompositions of I and the selection differential on body size showed that over 95% of the selection on females arose from the premating phase. We also found evidence for a trade-off between selection phases, where multiply mating females had significantly lower offspring survivorship compared to singly mated females. In males, variance in relative fitness arose mainly from the number of eggs received per copulation and a small number of males who failed to mate. Overall, our study exemplifies a general approach for the decomposition of total selection into premating and postmating phases to understand the interplay among components of natural and sexual selection that conspire to shape sexually selected traits.

Promoting Science Learning and Scientific Identification through Contemporary Scientific Investigations

NASA Astrophysics Data System (ADS)

Van Horne, Katie

This dissertation investigates the implementation issues and the educational opportunities associated with "taking the practice turn" in science education. This pedagogical shift focuses instructional experiences on engaging students in the epistemic practices of science both to learn the core ideas of the disciplines, as well as to gain an understanding of and personal connection to the scientific enterprise. In Chapter 2, I examine the teacher-researcher co-design collaboration that supported the classroom implementation of a year-long, project-based biology curriculum that was under development. This study explores the dilemmas that arose when teachers implemented a new intervention and how the dilemmas arose and were managed throughout the collaboration of researchers and teachers and between the teachers. In the design-based research of Chapter 3, I demonstrate how students' engagement in epistemic practices in contemporary science investigations supported their conceptual development about genetics. The analysis shows how this involved a complex interaction between the scientific, school and community practices in students' lives and how through varied participation in the practices students come to write about and recognize how contemporary investigations can give them leverage for science-based action outside of the school setting. Finally, Chapter 4 explores the characteristics of learning environments for supporting the development of scientific practice-linked identities. Specific features of the learning environment---access to the intellectual work of the domain, authentic roles and accountability, space to make meaningful contributions in relation to personal interests, and practice-linked identity resources that arose from interactions in the learning setting---supported learners in stabilizing practice-linked science identities through their engagement in contemporary scientific practices. This set of studies shows that providing students with the tools and means of contemporary scientific inquiry allows them to gain conceptual development and proficiency with the scientific practices within the contexts of their lives, in ways that provided access to resources that promoted students' stabilization of practice-linked identities. For teachers implementing this instructional model in their classrooms, it brought up dilemmas and opportunities related to their school contexts and their personal history of instructional practices. The work collectively informs how interest-driven project-based science instruction can happen across a range of school contexts and how such models can support meaningful science learning and identification.

77 FR 55482 - Public Workshop on Marine Technology and Standards

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-10

... provide a unique opportunity for classification societies, industry groups, standards development... email at [email protected] . You may also contact Lieutenant Commander Ken Hettler, Office of Design and... provides a unique opportunity for classification societies, industry groups, standards development...

Charge Coupled Devices in Signal Processing Systems. Volume V. Final Report.

DTIC Science & Technology

1979-12-01

the Phase III program. At that time, mutual customer /contractor interest arose in a unique application area, involving manipulation of lists of...using half adders and "or" circuits. 4-35 3 b 2 b3 01 b *3b, *2 b 1 b2b 1 0 1 b, + + + + + + ++ r T 7 7 r* 7FA +-0j FA 147 7 7 1 77 7 7 TL NO.6 NO. 5...which the cell could be step-and- repeated into an array in the CAD system. In practice we found that the attendent custom skewing delay layout

Survival of the Friendliest: Homo sapiens Evolved via Selection for Prosociality.

PubMed

Hare, Brian

2017-01-03

The challenge of studying human cognitive evolution is identifying unique features of our intelligence while explaining the processes by which they arose. Comparisons with nonhuman apes point to our early-emerging cooperative-communicative abilities as crucial to the evolution of all forms of human cultural cognition, including language. The human self-domestication hypothesis proposes that these early-emerging social skills evolved when natural selection favored increased in-group prosociality over aggression in late human evolution. As a by-product of this selection, humans are predicted to show traits of the domestication syndrome observed in other domestic animals. In reviewing comparative, developmental, neurobiological, and paleoanthropological research, compelling evidence emerges for the predicted relationship between unique human mentalizing abilities, tolerance, and the domestication syndrome in humans. This synthesis includes a review of the first a priori test of the self-domestication hypothesis as well as predictions for future tests.

Angiographic Evaluation of Feeding Arteries of Hepatocellular Carcinoma in the Caudate Lobe of the Liver

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miyayama, Shiro, E-mail: s-miyayama@fukui.saiseikai.or.jp; Yamashiro, Masashi; Hattori, Yuki

2011-12-15

Purpose: To evaluate the origins of feeders of hepatocellular carcinoma (HCC) in the caudate lobe (S1). Materials and Methods: Eighty-eight HCCs (mean diameter 21.4 mm) were treated by chemoembolization. The tumor-feeding caudate artery was confirmed when a tumor stain was demonstrated on angiogram and iodized oil was accumulated into the HCC and S1 on computed tomography (CT). The origins were divided into R{sub 1} (right proximal), R{sub 2} (right distal), L{sub 1} (left proximal), L{sub 2} (left distal), A (anterior segmental), P (posterior segmental), M (middle hepatic or medial segmental), Ph (proper hepatic), Ch (common hepatic), and Ex (extrahepatic). Themore » origins of feeders supplying HCCs in the Spiegel lobe (SP; n = 36), the paracaval portion (PC; n = 38), and the caudate process (CP; n = 14) were also analyzed. Results: One hundred sixteen feeders were identified: 11 (9.5%) arose from R{sub 1}; 21 (18.1%) arose from R{sub 2}; nine arose (0.9%) from L{sub 1}; 15 (12.9%) arose from L{sub 2}; 24 (20.7%) arose from A; 25 (21.6%) arose from P; seven (6.0%) arose from M; one (0.9%) arose from Ph; and three (2.6%) arose from Ex. HCCs in the SP and the PC were fed by feeders from both hepatic arteries (the ratios of right to left were 3:2 and 3:1, respectively), and HCCs in the CP were dominantly fed by feeders from the right hepatic artery. Conclusion: The caudate artery most frequently arises from the right hepatic artery, followed with almost equal frequency by the left hepatic, the anterior segmental, and the posterior segmental artery. The origins of the caudate arteries differ according to the subsegmental locations.« less

Statistical lessons learned for designing cluster randomized pragmatic clinical trials from the NIH Health Care Systems Collaboratory Biostatistics and Design Core.

PubMed

Cook, Andrea J; Delong, Elizabeth; Murray, David M; Vollmer, William M; Heagerty, Patrick J

2016-10-01

Pragmatic clinical trials embedded within health care systems provide an important opportunity to evaluate new interventions and treatments. Networks have recently been developed to support practical and efficient studies. Pragmatic trials will lead to improvements in how we deliver health care and promise to more rapidly translate research findings into practice. The National Institutes of Health (NIH) Health Care Systems Collaboratory was formed to conduct pragmatic clinical trials and to cultivate collaboration across research areas and disciplines to develop best practices for future studies. Through a two-stage grant process including a pilot phase (UH2) and a main trial phase (UH3), investigators across the Collaboratory had the opportunity to work together to improve all aspects of these trials before they were launched and to address new issues that arose during implementation. Seven Cores were created to address the various considerations, including Electronic Health Records; Phenotypes, Data Standards, and Data Quality; Biostatistics and Design Core; Patient-Reported Outcomes; Health Care Systems Interactions; Regulatory/Ethics; and Stakeholder Engagement. The goal of this article is to summarize the Biostatistics and Design Core's lessons learned during the initial pilot phase with seven pragmatic clinical trials conducted between 2012 and 2014. Methodological issues arose from the five cluster-randomized trials, also called group-randomized trials, including consideration of crossover and stepped wedge designs. We outlined general themes and challenges and proposed solutions from the pilot phase including topics such as study design, unit of randomization, sample size, and statistical analysis. Our findings are applicable to other pragmatic clinical trials conducted within health care systems. Pragmatic clinical trials using the UH2/UH3 funding mechanism provide an opportunity to ensure that all relevant design issues have been fully considered in order to reliably and efficiently evaluate new interventions and treatments. The integrity and generalizability of trial results can only be ensured if rigorous designs and appropriate analysis choices are an essential part of their research protocols. © The Author(s) 2016.

Coal desulfurization in a rotary kiln combustor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cobb, J.T. Jr.

1991-04-22

The focus of our work during the first quarter of 1991 was on combustion tests at the PEDCO rotary kiln reactor at North American Rayon (NARCO) plant in Elizabethton, TN. The tests had essentially tow related objectives: (a) to obtain basic data on the combustion of anthracite culm in a rotary kiln reactor, and (b) upon the test results, determine how best to proceed with our own planned program at the Humphrey Charcoal kiln in Brookville, PA. The rationale for the tests at PEDCO arose from process analysis which posted red flags on the feasibility of burning low-grade, hard-to-burn fuelsmore » like anthracite culms, in the rotary kiln. The PEDCO unit afforded a unique opportunity to obtain some quick answers at low cost. Two different anthracite culm fuels were tested: a so-called Jeddo culm with an average heating value of 7000 Btu/lb, and a relatively poorer culm, and Emerald'' culm, with an average heating value of 5000 Btu/lb. An attempt was also made to burn a blend of the Emerald culm with bituminous coal in 75/25 percent proportions. This report describes the tests, their chronology, and preliminary results. As it turned out, the PEDCO unit is not configured properly for the combustion of anthracite culm. As a result, it proved difficult to achieve a sustained period of steady-state combustion operation, and combustion efficiencies were low even when supplemental fuel was used to aid combustion of the culm. 1 fig., 2 tabs.« less

The Worldwide Interplanetary Scintillation (IPS) Stations (WIPSS) Network October 2016 Observing Campaign: Initial WIPSS Data Analyses

NASA Astrophysics Data System (ADS)

Bisi, M. M.; Fallows, R. A.; Jackson, B. V.; Tokumaru, M.; Gonzalez-Esparza, A.; Morgan, J.; Chashei, I. V.; Mejia-Ambriz, J.; Tyul'bashev, S. A.; Manoharan, P. K.; De la Luz, V.; Aguilar-Rodriguez, E.; Yu, H. S.; Barnes, D.; Chang, O.; Odstrcil, D.; Fujiki, K.; Shishov, V.

2017-12-01

Interplanetary Scintillation (IPS) allows for the determination of velocity and a proxy for plasma density to be made throughout the corona and inner heliosphere. Where sufficient observations are undertaken, the results can be used as input to the University of California, San Diego (UCSD) three-dimensional (3-D) time-dependent tomography suite to allow for the full 3-D reconstruction of both velocity and density throughout the inner heliosphere. By combining IPS results from multiple observing locations around the planet, we can increase both the temporal and spatial coverage across the whole of the inner heliosphere and hence improve forecast capability. During October 2016, a unique opportunity arose whereby the European-based LOw Frequency ARray (LOFAR) radio telescope was used to make nearly four weeks of continuous observations of IPS as a heliospheric space-weather trial campaign. This was expanded into a global effort to include observations of IPS from the Murchison Widefield Array (MWA) in Western Australia and many more observations from various IPS-dedicated WIPSS Network systems. LOFAR is a next-generation low-frequency radio interferometer capable of observing in the radio frequency range 10-250 MHz, nominally with up to 80 MHz bandwidth at a time. MWA in Western Australia is capable of observing in the 80-300 MHz frequency range nominally using up to 32 MHz of bandwidth. IPS data from LOFAR, ISEE, the MEXican Array Radio Telescope (MEXART), and, where possible, other WIPSS Network systems (such as LPI-BSA and Ooty), will be used in this study and we will present some initial findings for these data sets. We also make a first attempt at the 3-D reconstruction of multiple pertinent WIPSS results in the UCSD tomography. We will also try to highlight some of the potential future tools that make LOFAR a very unique system to be able to test and validate a whole plethora of IPS analysis methods with the same set of IPS data.

Biotite weathering in a natural forest setting near Derome, Sweden

NASA Astrophysics Data System (ADS)

Balogh-Brunstad, Z.; Negrich, K.; Hassenkam, T.; Wallander, H.; Stipp, S. L.

2011-12-01

Chemical weathering is a key process in non-nitrogen nutrient acquisition by microbes, fungi and plants. Biotite is commonly the major source of potassium, magnesium and iron. A unique opportunity arose to study natural weathering of biotite by mixed conifer and hardwood forest vegetation and associated microbes and fungi at an abandoned mine site. After the mining stopped over 30 years ago biotite was left behind in piles and the forest vegetation progressively colonized the site. Samples were collected from the top 40 cm of the biotite piles in a vicinity of pine, spruce and birch trees and included some young seedlings. Macroscopic observations documented abundant hyphal growth between the sheets of biotite. We hypothesized that fungal hyphae grow between the sheets to explore the nutrient source and weather the biotite leaving hyphal-sized etched channels on the basal surfaces. Biotite surfaces were examined with atomic force microscopy (AFM) and environmental scanning electron microscopy (ESEM) in their natural state and after removing the biological material from the mineral surfaces. The ESEM images show extensive hyphal colonization and patchy biofilm cover of the entire biotite surface on and within the sheets and at the edges of the particles. Fungal hyphae did not attach strongly to the basal surfaces of the biotite flakes as a result of small particles on the surfaces and the uneven micro-topography. The AFM images illustrate a complex microbial community around the fungal hyphae and detailed fungal morphology. High resolution AFM images show unique globular features of diameter 10-100 nm on all biofilm surfaces. However, removal of the biological material resulted in smooth and un-etched surfaces indicating that either our removal techniques are too invasive and destroy the surface layers of interest, or the etching of the basal surface is not the main mechanism for chemical weathering and base-cation nutrient immobilization in this natural setting. Species-specific interactions at the biofilm-microbe-fungus-mineral interface and spatial distribution in the biotite pile are under further investigation.

Travelling for earlier surgical treatment: the patient's view.

PubMed Central

Stewart, M; Donaldson, L J

1991-01-01

As part of the northern region's programme within the national waiting list initiative, schemes have been funded to test the feasibility and acceptability of offering patients the opportunity to travel further afield in order to receive earlier treatment. A total of 484 patients experiencing a long wait for routine surgical operations in the northern region were offered the opportunity to receive earlier treatment outside their local health district; 74% of the patients accepted the offer. The initiative was well received by the participating patients and the majority stated that if the need arose on a future occasion they would prefer to travel for treatment rather than have to wait for lengthy periods for treatment at their local hospital. These findings, interpreted in the light of the National Health Service reforms introduced in April 1991, suggest that for some types of care, patients would welcome greater flexibility in the placing of contracts, not merely reinforcement of historical patterns of referral. PMID:1823553

HIGH RATES OF EVOLUTION PRECEDED THE ORIGIN OF BIRDS

PubMed Central

Puttick, Mark N; Thomas, Gavin H; Benton, Michael J; Polly, P David

2014-01-01

The origin of birds (Aves) is one of the great evolutionary transitions. Fossils show that many unique morphological features of modern birds, such as feathers, reduction in body size, and the semilunate carpal, long preceded the origin of clade Aves, but some may be unique to Aves, such as relative elongation of the forelimb. We study the evolution of body size and forelimb length across the phylogeny of coelurosaurian theropods and Mesozoic Aves. Using recently developed phylogenetic comparative methods, we find an increase in rates of body size and body size dependent forelimb evolution leading to small body size relative to forelimb length in Paraves, the wider clade comprising Aves and Deinonychosauria. The high evolutionary rates arose primarily from a reduction in body size, as there were no increased rates of forelimb evolution. In line with a recent study, we find evidence that Aves appear to have a unique relationship between body size and forelimb dimensions. Traits associated with Aves evolved before their origin, at high rates, and support the notion that numerous lineages of paravians were experimenting with different modes of flight through the Late Jurassic and Early Cretaceous. PMID:24471891

A patient with a unique frameshift mutation in GPC3, causing Simpson-Golabi-Behmel syndrome, presenting with craniosynostosis, penoscrotal hypospadias, and a large prostatic utricle.

PubMed

Villarreal, Diana D; Villarreal, Humberto; Paez, Ana Maria; Peppas, Dennis; Lynch, Jane; Roeder, Elizabeth; Powers, George C

2013-12-01

We present a Hispanic male with the clinical and molecular diagnosis of Simpson-Golabi-Behmel syndrome (SGBS). The patient was born with multiple anomalies not entirely typical of SGBS patients, including penoscrotal hypospadias, a large prostatic utricle, and left coronal craniosynostosis. In addition, he demonstrated endocrine anomalies including a low random cortisol level suspicious for adrenal insufficiency and low testosterone level. To our knowledge, this is the first report of a prostatic utricle in SGBS and the second report of craniosynostosis. The unique disease-causing mutation likely arose de novo in the mother. It is a deletion-insertion that leads to a frameshift at the p.p. S359 [corrected] residue of GPC3 and a premature stop codon after five more amino acids. p. S359 [corrected] is the same residue that is normally cleaved by the Furin convertase, although the significance of this novel mutation with respect to the patient's multiple anomalies is unknown. We present this case as the perinatal course of a patient with unique features of SGBS and a confirmed molecular diagnosis. © 2013 Wiley Periodicals, Inc.

Earth's early biosphere

NASA Technical Reports Server (NTRS)

Des Marais, D. J.

1998-01-01

Understanding our own early biosphere is essential to our search for life elsewhere, because life arose on Earth very early and rocky planets shared similar early histories. The biosphere arose before 3.8 Ga ago, was exclusively unicellular and was dominated by hyperthermophiles that utilized chemical sources of energy and employed a range of metabolic pathways for CO2 assimilation. Photosynthesis also arose very early. Oxygenic photosynthesis arose later but still prior to 2.7 Ga. The transition toward the modern global environment was paced by a decline in volcanic and hydrothermal activity. These developments allowed atmospheric O2 levels to increase. The O2 increase created new niches for aerobic life, most notably the more advanced Eukarya that eventually spawned the megascopic fauna and flora of our modern biosphere.

Dealing with the tension: how residents seek autonomy and participation in the workplace.

PubMed

Olmos-Vega, Francisco M; Dolmans, Diana H J M; Vargas-Castro, Nicolas; Stalmeijer, Renée E

2017-07-01

The workplace can be a strenuous setting for residents: although it offers a wealth of learning opportunities, residents find themselves juggling their responsibilities. Even though supervisors regulate what is afforded to residents, the former find it difficult to strike the proper balance between residents' independence and support, which could create tensions. But what tensions do residents experience during clinical supervision and how do they cope with them to maximise their learning opportunities? Understanding how residents act on different affordances in the workplace is of paramount importance, as it influences their learning. Residents from different levels of training and disciplines participated in three focus groups (n = 19) and 10 semi-structured interviews (n = 10). The authors recruited these trainees using purposive and convenience sampling. Audio-recordings were transcribed verbatim and the ensuing scripts were analysed using a constructivist grounded theory methodology. Residents reported that the autonomy and practice opportunities given by their supervisors were either excessive or too limited, and both were perceived as tensions. When in excess, trainees enlisted the help of their supervisor or peers, depending on how safe they recognised the learning environment to be. When practice opportunities were curtailed, trainees tried to negotiate more if they felt the learning environment was safe. When they did not, trainees became passive observers. Learning from each engagement was subject to the extent of intersubjectivity achieved between the actors involved. Tensions arose when supervisors did not give trainees the desired degree of autonomy and opportunities to participate. Trainees responded in various ways to maximise their learning opportunities. For these different engagement-related responses to enhance workplace learning in specialty training, achieving intersubjectivity between trainee and supervisor seems foundational. © 2017 John Wiley & Sons Ltd and The Association for the Study of Medical Education.

Cyberdrugs: a cross-sectional study of online pharmacies characteristics.

PubMed

Orizio, Grazia; Schulz, Peter; Domenighini, Serena; Caimi, Luigi; Rosati, Cristina; Rubinelli, Sara; Gelatti, Umberto

2009-08-01

As e-commerce and online pharmacies (OPs) arose, the potential impact of the Internet on the world of health shifted from merely the spread of information to a real opportunity to acquire health services directly. Aim of the study was to investigate the offer of prescription drugs in OPs, analysing their characteristics, using the content analysis method. The research performed using the Google search engine led to an analysis of 118 online pharmacies. Only 51 (43.2%) of them stated their precise location. Ninety-six (81.4%) online pharmacies did not require a medical prescription from the customer's physician. Online pharmacies rise complex issues in terms of patient-doctor relationship, consumer empowerment, drug quality, regulation and public health implications.

Minimizing opportunity costs to aquatic connectivity restoration while controlling an invasive species.

PubMed

Milt, Austin W; Diebel, Matthew W; Doran, Patrick J; Ferris, Michael C; Herbert, Matthew; Khoury, Mary L; Moody, Allison T; Neeson, Thomas M; Ross, Jared; Treska, Ted; O'Hanley, Jesse R; Walter, Lisa; Wangen, Steven R; Yacobson, Eugene; McIntyre, Peter B

2018-03-08

Controlling invasive species is critical for conservation but can have unintended consequences for native species and divert resources away from other efforts. This dilemma occurs on a grand scale in the North American Great Lakes, where dams and culverts block tributary access to habitat of desirable fish species and are a lynchpin of long-standing efforts to limit ecological damage inflicted by the invasive, parasitic sea lamprey (Petromyzon marinus). Habitat restoration and sea-lamprey control create conflicting goals for managing aging infrastructure. We used optimization to minimize opportunity costs of habitat gains for 37 desirable migratory fishes that arose from restricting sea lamprey access (0-25% increase) when selecting barriers for removal under a limited budget (US$1-105 million). Imposing limits on sea lamprey habitat reduced gains in tributary access for desirable species by 15-50% relative to an unconstrained scenario. Additional investment to offset the effect of limiting sea-lamprey access resulted in high opportunity costs for 30 of 37 species (e.g., an additional US$20-80 million for lake sturgeon [Acipenser fulvescens]) and often required ≥5% increase in sea-lamprey access to identify barrier-removal solutions adhering to the budget and limiting access. Narrowly distributed species exhibited the highest opportunity costs but benefited more at less cost when small increases in sea-lamprey access were allowed. Our results illustrate the value of optimization in limiting opportunity costs when balancing invasion control against restoration benefits for diverse desirable species. Such trade-off analyses are essential to the restoration of connectivity within fragmented rivers without unleashing invaders. © 2018 Society for Conservation Biology.

Haplotype analysis of the 185delAG BRCA1 mutation in ethnically diverse populations

PubMed Central

Laitman, Yael; Feng, Bing-Jian; Zamir, Itay M; Weitzel, Jeffrey N; Duncan, Paul; Port, Danielle; Thirthagiri, Eswary; Teo, Soo-Hwang; Evans, Gareth; Latif, Ayse; Newman, William G; Gershoni-Baruch, Ruth; Zidan, Jamal; Shimon-Paluch, Shani; Goldgar, David; Friedman, Eitan

2013-01-01

The 185delAG* BRCA1 mutation is encountered primarily in Jewish Ashkenazi and Iraqi individuals, and sporadically in non-Jews. Previous studies estimated that this is a founder mutation in Jewish mutation carriers that arose before the dispersion of Jews in the Diaspora ∼2500 years ago. The aim of this study was to assess the haplotype in ethnically diverse 185delAG* BRCA1 mutation carriers, and to estimate the age at which the mutation arose. Ethnically diverse Jewish and non-Jewish 185delAG*BRCA1 mutation carriers and their relatives were genotyped using 15 microsatellite markers and three SNPs spanning 12.5 MB, encompassing the BRCA1 gene locus. Estimation of mutation age was based on a subset of 11 markers spanning a region of ∼5 MB, using a previously developed algorithm applying the maximum likelihood method. Overall, 188 participants (154 carriers and 34 noncarriers) from 115 families were included: Ashkenazi, Iraq, Kuchin-Indians, Syria, Turkey, Iran, Tunisia, Bulgaria, non-Jewish English, non-Jewish Malaysian, and Hispanics. Haplotype analysis indicated that the 185delAG mutation arose 750–1500 years ago. In Ashkenazim, it is a founder mutation that arose 61 generations ago, and with a small group of founder mutations was introduced into the Hispanic population (conversos) ∼650 years ago, and into the Iraqi–Jewish community ∼450 years ago. The 185delAG mutation in the non-Jewish populations in Malaysia and the UK arose at least twice independently. We conclude that the 185delAG* BRCA1 mutation resides on a common haplotype among Ashkenazi Jews, and arose about 61 generations ago and arose independently at least twice in non-Jews. PMID:22763381

Tunable organization of cellulose nanocrystals for controlled thermal and optical response

NASA Astrophysics Data System (ADS)

Diaz A., Jairo A.

The biorenewable nature of cellulose nanocrystals (CNCs) has opened up new opportunities for cost-effective, sustainable materials design. By taking advantage of their distinctive structural properties and self-assembly, promising applications have started to nurture the fields of flexible electronics, biomaterials, and nanocomposites. CNCs exhibit two fundamental characteristics: rod-like morphology (5-20 nm wide, 50-500 nm long), and lyotropic behavior (i.e., liquid crystalline mesophases formed in solvents), which offer unique opportunities for structural control and fine tuning of thermal and optical properties based on a proper understanding of their individual behavior and interactions at different length scales. In the present work, we attempt to provide an integral description of the influence of single crystals in the thermal and optical response exhibited by nanostructured films. Our approach involved the connection of experimental evidence with predictions of molecular dynamics (MD) simulations. In order to assess the effect of CNC orientation in the bulk response, we produced cellulose nanostructured films under two different mechanisms, namely, self-organization and shear orientation. Self-organized nanostructured films exhibited the typical iridescent optical reflection generated by chiral nematic organization. Shear oriented films disrupted the cholesteric organization, generating highly aligned structures with high optical transparency. The resultant CNC organization present in all nanostructured films was estimated by a second order statistical orientational distribution based on two- dimensional XRD signals. A new method to determine the coefficient of thermal expansion (CTE) in a contact-free fashion was developed to properly characterize the thermal expansion of thin soft films by excluding other thermally activated phenomena. The method can be readily extended to other soft materials to accurately measure thermal strains in a non-destructive way. By evaluating the magnitude of film CTEs relative to those of individual CNC crystals, we highlighted the significant role played by crystalline interfaces. Likewise, after measuring the thermal conductivity of a single crystal and CNC films having multiple organizations, the interfacial thermal resistance arose as a governing factor for heat transport. We will offer further insights into the intricate connection of thermal and optical properties towards a future efficient manufacture and optimal CNC based-materials design.

Characteristics and expression patterns of the aldehyde dehydrogenase (ALDH) gene superfamily of foxtail millet (Setaria italica L.).

PubMed

Chen, Zhu; Chen, Ming; Xu, Zhao-shi; Li, Lian-cheng; Chen, Xue-ping; Ma, You-zhi

2014-01-01

Recent genomic sequencing of the foxtail millet, an abiotic, stress-tolerant crop, has provided a great opportunity for novel gene discovery and functional analysis of this popularly-grown grass. However, few stress-mediated gene families have been studied. Aldehyde dehydrogenases (ALDHs) comprise a gene superfamily encoding NAD (P) +-dependent enzymes that play the role of "aldehyde scavengers", which indirectly detoxify cellular ROS and reduce the effect of lipid peroxidation meditated cellular toxicity under various environmental stresses. In the current paper, we identified a total of 20 ALDH genes in the foxtail millet genome using a homology search and a phylogenetic analysis and grouped them into ten distinct families based on their amino acid sequence identity. Furthermore, evolutionary analysis of foxtail millet reveals that both tandem and segmental duplication contributed significantly to the expansion of its ALDH genes. The exon-intron structures of members of the same family in foxtail millet or the orthologous genes in rice display highly diverse distributions of their exonic and intronic regions. Also, synteny analysis shows that the majority of foxtail millet and rice ALDH gene homologs exist in the syntenic blocks between the two, implying that these ALDH genes arose before the divergence of cereals. Semi-quantitative and real-time quantitative PCR data reveals that a few SiALDH genes are expressed in an organ-specific manner and that the expression of a number of foxtail millet ALDH genes, such as, SiALDH7B1, SiALDH12A1 and SiALDH18B2 are up-regulated by osmotic stress, cold, H2O2, and phytohormone abscisic acid (ABA). Furthermore, the transformation of SiALDH2B2, SiALDH10A2, SiALDH5F1, SiALDH22A1, and SiALDH3E2 into Escherichia coli (E.coli) was able to improve their salt tolerance. Taken together, our results show that genome-wide identification characteristics and expression analyses provide unique opportunities for assessing the functional roles of foxtail millet ALDH genes in stress responses.

Disparities in new graduate transition from multiple stakeholder perspectives.

PubMed

Adamack, Monica; Rush, Kathy L

2014-09-01

The purpose of this qualitative study was to understand multiple stakeholder perspectives of new graduate (NG) transition programs. It was part of a larger mixed-methods study (2011) designed to provide a comprehensive assessment of new graduate nurse transition best practices, across six British Columbia health authorities. Data collection involved individual interviews with academic nurse educators (n=4) and separate focus groups with new graduate (n=48) and front-line nurse leaders (n=69). Disparity emerged as the overriding theme and described differences between stakeholder group perspectives, between expectations and reality, and within and across programs. Four disparities emerged: entry-level education and practice, perspectives on employment and career planning, transition program elements and support. Despite general satisfaction with undergraduate preparation, theory-practice gaps were identified. New Graduates experienced misalignments between their employment expectations and their realities. The employed student nurse program in which many new graduates had participated did not always yield employment, but when it did, differences in transitional expectations arose between new graduates and leaders. There was considerable variation across and within provincial new graduate programs with respect to orientation, supernumerary time and preceptorship characteristics, including lack of training. Disparities arose in the nature, amount of and access to support and the monitoring of new graduate progress. Findings reinforced organizational complexities and the importance of communication across education and practice sectors. This paper uncovers the tensions between the perspectives of new graduates and nurse leaders about transitional programs and opens the opportunity to collaborate in aligning the perspectives.

Zebrafish heart failure models: opportunities and challenges.

PubMed

Shi, Xingjuan; Chen, Ru; Zhang, Yu; Yun, Junghwa; Brand-Arzamendi, Koroboshka; Liu, Xiangdong; Wen, Xiao-Yan

2018-05-03

Heart failure is a complex pathophysiological syndrome of pumping functional failure that results from injury, infection or toxin-induced damage on the myocardium, as well as genetic influence. Gene mutations associated with cardiomyopathies can lead to various pathologies of heart failure. In recent years, zebrafish, Danio rerio, has emerged as an excellent model to study human cardiovascular diseases such as congenital heart defects, cardiomyopathy, and preclinical development of drugs targeting these diseases. In this review, we will first summarize zebrafish genetic models of heart failure arose from cardiomyopathy, which is caused by mutations in sarcomere, calcium or mitochondrial-associated genes. Moreover, we outline zebrafish heart failure models triggered by chemical compounds. Elucidation of these models will improve the understanding of the mechanism of pathogenesis and provide potential targets for novel therapies.

Results from On-Orbit Testing of the Fram Memory Test Experiment on the Fastsat Micro-Satellite

NASA Technical Reports Server (NTRS)

MacLeod, Todd C.; Sims, W. Herb; Varnavas, Kosta A.; Ho, Fat D.

2011-01-01

NASA is planning on going beyond Low Earth orbit with manned exploration missions. The radiation environment for most Low Earth orbit missions is harsher than at the Earth's surface but much less harsh than deep space. Development of new electronics is needed to meet the requirements of high performance, radiation tolerance, and reliability. The need for both Volatile and Non-volatile memory has been identified. Emerging Non-volatile memory technologies (FRAM, C-RAM,M-RAM, R-RAM, Radiation Tolerant FLASH, SONOS, etc.) need to be investigated for use in Space missions. An opportunity arose to fly a small memory experiment on a high inclination satellite (FASTSAT). An off-the-shelf 512K Ramtron FRAM was chosen to be tested in the experiment.

EPA versus Colorado: national unity versus state flexibility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Foster, T.

When the Environmental Protection Agency (EPA) reviewed Colorado's National Pollutant Discharge Elimination System (NPDES) permit program under the federal Clean Water Act, it found a conflict between federal and state perspectives on how much flexibility from national norms is allowable for state peculiarities. Colorado's hydrology and geography seemed to justify a water quality program providing for various opportunities to review water quality decisions before requiring advanced waste treatment (AWT), and to avoid AWT when justified. Conflict arose because few streams in Colorado provide mixing zones or dilution that Eastern streams enjoy. The author reviews the legal developments as EPA arguedmore » for national uniformity and Colorado for flexibility. States might be tempted to return permitting programs to EPA if they cannot retain enough flexibility in the law to protect their interests.« less

Natural Product Inspired Hsp90 N-Terminal Inhibitors for the Treatment of Cancer: From Bench to Bedside

PubMed Central

Blagg, Brian S. J.

2015-01-01

The 90 kDa heat shock proteins (Hsp90) are responsible for the conformational maturation of nascent polypeptides and the rematuration of denatured proteins. Proteins dependent upon Hsp90 are associated with all six hallmarks of cancer. Upon Hsp90 inhibition, protein substrates are degraded via the ubiquitin-proteasome pathway. Consequentially, inhibition of Hsp90 offers a therapeutic opportunity for the treatment of cancer. Natural product inhibitors of Hsp90 have been identified in vitro, which have served as leads for the development of more efficacious inhibitors and analogs that have entered clinical trials. This review highlights the development of natural product analogs, as well as the development of clinically important inhibitors that arose from natural products. PMID:26010985

Cutting edge issues in allergy and clinical immunology.

PubMed

Matthias, Torsten; Shoenfeld, Yehuda

2007-02-01

Approximately every 5 yr, Clinical Reviews in Allergy and Immunology deviates from its usual practice of publishing volumes devoted to one theme to including papers that cover a range of subjects. This issue is one such exception and arose following a symposium at the International Institute for Research in Autoimmune Diseases named AESKU.KIPP Institute at their Wendelsheim facility. The AESKU.KIPP Institute was a particularly venue because it was initially established by a German diagnostic company and a Swiss benefactor, Karl- Heinz Kipp. The goal of the Institute was to develop a unique atmosphere to encourage original research in the field of autoimmunity and clinical immunology. The thought was to create an institute where young scientists from throughout the world could come for short periods of time to learn newer methodologies in both clinical immunology and also molecular biology. This theme contains several of the papers presented at the opening of the Institute and are incorporated herein because they focus on several unique aspects of clinical immunology, often referred to as the mosaic of autoimmunity.

Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8)

PubMed Central

Russo, James J.; Bohenzky, Roy A.; Chien, Ming-Cheng; Chen, Jing; Yan, Ming; Maddalena, Dawn; Parry, J. Preston; Peruzzi, Daniela; Edelman, Isidore S.; Chang, Yuan; Moore, Patrick S.

1996-01-01

The genome of the Kaposi sarcoma-associated herpesvirus (KSHV or HHV8) was mapped with cosmid and phage genomic libraries from the BC-1 cell line. Its nucleotide sequence was determined except for a 3-kb region at the right end of the genome that was refractory to cloning. The BC-1 KSHV genome consists of a 140.5-kb-long unique coding region flanked by multiple G+C-rich 801-bp terminal repeat sequences. A genomic duplication that apparently arose in the parental tumor is present in this cell culture-derived strain. At least 81 ORFs, including 66 with homology to herpesvirus saimiri ORFs, and 5 internal repeat regions are present in the long unique region. The virus encodes homologs to complement-binding proteins, three cytokines (two macrophage inflammatory proteins and interleukin 6), dihydrofolate reductase, bcl-2, interferon regulatory factors, interleukin 8 receptor, neural cell adhesion molecule-like adhesin, and a D-type cyclin, as well as viral structural and metabolic proteins. Terminal repeat analysis of virus DNA from a KS lesion suggests a monoclonal expansion of KSHV in the KS tumor. PMID:8962146

Structural Rearrangement in an RsmA/CsrA Ortholog of Pseudomonas aeruginosa Creates a Dimeric RNA-Binding Protein, RsmN

PubMed Central

Morris, Elizabeth R.; Hall, Gareth; Li, Chan; Heeb, Stephan; Kulkarni, Rahul V.; Lovelock, Laura; Silistre, Hazel; Messina, Marco; Cámara, Miguel; Emsley, Jonas; Williams, Paul; Searle, Mark S.

2013-01-01

Summary In bacteria, the highly conserved RsmA/CsrA family of RNA-binding proteins functions as global posttranscriptional regulators acting on mRNA translation and stability. Through phenotypic complementation of an rsmA mutant in Pseudomonas aeruginosa, we discovered a family member, termed RsmN. Elucidation of the RsmN crystal structure and that of the complex with a hairpin from the sRNA, RsmZ, reveals a uniquely inserted α helix, which redirects the polypeptide chain to form a distinctly different protein fold to the domain-swapped dimeric structure of RsmA homologs. The overall β sheet structure required for RNA recognition is, however, preserved with compensatory sequence and structure differences, allowing the RsmN dimer to target binding motifs in both structured hairpin loops and flexible disordered RNAs. Phylogenetic analysis indicates that, although RsmN appears unique to P. aeruginosa, homologous proteins with the inserted α helix are more widespread and arose as a consequence of a gene duplication event. PMID:23954502

An anomalous origin of the gastrosplenic trunk and common hepatic artery arising independently from the abdominal aorta: a case report using MDCT angiography.

PubMed

Iacob, Nicoleta; Pusztai, Agneta Maria; Miclăuş, Graţian Dragoslav; Pop, Elena; Matusz, Petru

2018-01-01

The authors describe a case of a 61-year-old female patient, which presented on multidetector computed tomographic (MDCT) angiography a gastrosplenic trunk (GST) and common hepatic artery (CHA) arose independently from abdominal aorta (AA). The GST arose from the anterior wall of the AA, at the level of upper edge of the L1 vertebral body. The left gastric artery (LGA) arose from the superior wall of the GST. The splenic artery (SA) continuous the path of GST. The CHA arose from the anterior wall of the AA, at the level of upper one third of the L1 vertebral body, at 15.3 mm above the origin of superior mesenteric artery (SMA). The incidence and developmental and clinical significance of this vascular variation is discussed with a detailed review of the literature.

Unique challenges and opportunities for Northeastern U.S. crop production in a changing climate

USDA-ARS?s Scientific Manuscript database

Climate change may both exacerbate the vulnerabilities and open up new opportunities for farming in the Northeastern United States. Among the opportunities are double-cropping and new crop options that may come with warmer temperatures and a longer frost-free period. However, prolonged periods of sp...

Spatial partitioning and asymmetric hybridization among sympatric coastal steelhead trout (Oncorhynchus mykiss irideus), coastal cutthroat trout (O. clarki clarki) and interspecific hybrids

USGS Publications Warehouse

Ostberg, C.O.; Slatton, S.L.; Rodriguez, R.J.

2004-01-01

Hybridization between sympatric species provides unique opportunities to examine the contrast between mechanisms that promote hybridization and maintain species integrity. We surveyed hybridization between sympatric coastal steelhead (Oncorhynchus mykiss irideus) and coastal cutthroat trout (O. clarki clarki) from two streams in Washington State, Olsen Creek (256 individuals sampled) and Jansen Creek (431 individuals sampled), over a 3-year period. We applied 11 O. mykiss-specific nuclear markers, 11 O. c. clarki-specific nuclear markers and a mitochondrial DNA marker to assess spatial partitioning among species and hybrids and determine the directionality of hybridization. F1 and post-F1 hybrids, respectively, composed an average of 1.2% and 33.6% of the population sampled in Jansen Creek, and 5.9% and 30.4% of the population sampled in Olsen Creek. A modest level of habitat partitioning among species and hybrids was detected. Mitochondrial DNA analysis indicated that all F 1 hybrids (15 from Olsen Creek and five from Jansen Creek) arose from matings between steelhead females and cutthroat males implicating a sneak spawning behaviour by cutthroat males. First-generation cutthroat backcrosses contained O. c. clarki mtDNA more often than expected suggesting natural selection against F1 hybrids. More hybrids were backcrossed toward cutthroat than steelhead and our results indicate recurrent hybridization within these creeks. Age analysis demonstrated that hybrids were between 1 and 4 years old. These results suggest that within sympatric salmonid hybrid zones, exogenous processes (environmentally dependent factors) help to maintain the distinction between parental types through reduced fitness of hybrids within parental environments while divergent natural selection promotes parental types through distinct adaptive advantages of parental phenotypes.

Haplotype Sharing Provides Insights into Fine-Scale Population History and Disease in Finland.

PubMed

Martin, Alicia R; Karczewski, Konrad J; Kerminen, Sini; Kurki, Mitja I; Sarin, Antti-Pekka; Artomov, Mykyta; Eriksson, Johan G; Esko, Tõnu; Genovese, Giulio; Havulinna, Aki S; Kaprio, Jaakko; Konradi, Alexandra; Korányi, László; Kostareva, Anna; Männikkö, Minna; Metspalu, Andres; Perola, Markus; Prasad, Rashmi B; Raitakari, Olli; Rotar, Oxana; Salomaa, Veikko; Groop, Leif; Palotie, Aarno; Neale, Benjamin M; Ripatti, Samuli; Pirinen, Matti; Daly, Mark J

2018-05-03

Finland provides unique opportunities to investigate population and medical genomics because of its adoption of unified national electronic health records, detailed historical and birth records, and serial population bottlenecks. We assembled a comprehensive view of recent population history (≤100 generations), the timespan during which most rare-disease-causing alleles arose, by comparing pairwise haplotype sharing from 43,254 Finns to that of 16,060 Swedes, Estonians, Russians, and Hungarians from geographically and linguistically adjacent countries with different population histories. We find much more extensive sharing in Finns, with at least one ≥ 5 cM tract on average between pairs of unrelated individuals. By coupling haplotype sharing with fine-scale birth records from more than 25,000 individuals, we find that although haplotype sharing broadly decays with geographical distance, there are pockets of excess haplotype sharing; individuals from northeast Finland typically share several-fold more of their genome in identity-by-descent segments than individuals from southwest regions. We estimate recent effective population-size changes through time across regions of Finland, and we find that there was more continuous gene flow as Finns migrated from southwest to northeast between the early- and late-settlement regions than was dichotomously described previously. Lastly, we show that haplotype sharing is locally enriched by an order of magnitude among pairs of individuals sharing rare alleles and especially among pairs sharing rare disease-causing variants. Our work provides a general framework for using haplotype sharing to reconstruct an integrative view of recent population history and gain insight into the evolutionary origins of rare variants contributing to disease. Copyright © 2018 American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

A case study of collaboration in science education: Integrating informal learning experiences into the school curriculum

NASA Astrophysics Data System (ADS)

Robertson, Amy Michelle

This is a study of a collaboration between multiple stakeholders in science education for the purpose of creating educational field trip experiences. The collaboration involves four major facets of science education: formal education at the elementary and university levels, informal education, and educational research. The primary participants in the collaboration include two elementary school teachers, a scientist from a local university, an informal educator from an environmental education site, and the researcher acting as a participant observer. The coming together of these different sides of science education provided a unique opportunity to explore the issues and experiences that emerged as such a partnership was formed and developed. Strongly influenced by action research, this study is a qualitative case study. The data was collected by means of observation, semi-structured interviews, and written document review, in order to provide both a descriptive and an interpretive account of this collaboration. The final analysis integrates a description of the participants' experiences as evidenced in the data with the issues that arose from these experiences. The evolution of the collaborators' roles was examined, as was the development of shared vision. In this study, there were several factors that significantly affected the progress towards a shared vision and a successful collaboration. These factors include time, communication, understanding others' perspectives, dedication and ownership, as well as the collaborative environment. Each collaborator benefited both professionally and personally from their participation in the collaboration. In addition, the students gained cognitively, affectively, and socially from the educational experiences created through the collaboration. Steps, such as working towards communication and understanding others' perspectives, should continue to be taken to ensure the collaboration continues beyond the term of the current key participants.

Rationale and operational plan for a U.S. high-altitude magnetic survey

USGS Publications Warehouse

Hildenbrand, Thomas G.; Acuna, Mario; Bracken, Robert E.; Hardwick, Doug; Hinze, William J.; Keller, Gordon R.; Phillips, Jeff; Roest, Walter

2002-01-01

On August 8, 2002, twenty-one scientists from the federal, private and academic sectors met at a workshop in Denver, Co., to discuss the feasibility of collecting magnetic anomaly data on a Canberra aircraft (Figure 1). The need for this 1-day workshop arose because of an exciting and cost-effective opportunity to collect invaluable magnetic anomaly data during a Canberra mission over the U.S. in 2003 and 2004. High Altitude Mapping Missions (HAMM) is currently planning a mission to collect Interferometric Synthetic Aperture Radar (IFSAR) imagery at an altitude of about 15 km and with a flight-line spacing of about 18 km over the conterminous U.S. and Alaska. The additional collection of total and vector magnetic field data would represent a secondary mission objective (i.e., a "piggy-back" magnetometer system). Because HAMM would fund the main flight costs of the mission, the geomagnetic community would obtain invaluable magnetic data at a nominal cost. These unique data would provide new insights on fundamental tectonic and thermal processes and give a new view of the structural and lithologic framework of the crust and possibly the upper mantle. This document highlights: (1) the reasons to conduct this national survey and (2) a preliminary operational plan to collect high-altitude magnetic data of a desired quality and for the expected resources. Although some operational plan issues remain to be resolved, the important conclusions of the workshop are that the Canberra is a very suitable platform to measure the magnetic field and that the planned mission will result in quality high-altitude magnetic data to greatly expand the utility of our national magnetic database.

Making Meaning of von Hagens' Body Worlds: Towards an Interdisciplinary Approach to Science Exhibitions

NASA Astrophysics Data System (ADS)

Dubek, Michelle Melodie

Body Worlds is a traveling exhibition of plastinated human cadavers that offers the general public an opportunity to experience the human body in a unique way. It has been met with controversy and awe; public reactions and responses have been mixed. This case study research explored visitor responses to this controversial science exhibition, and examined the meaning visitors made of their experience. Specifically, the following research questions directed this study: Within the context of the Body Worlds exhibition: (a) What meaning did visitors make and how did they respond to the exhibits? (b) What tensions and issues arose for visitors? and (c) What did this type of exhibition convey about the changing role of science centres and the nature of their exhibitions? The primary sources of data for this study were 46 semi-structured interviews with visitors to the exhibition, observation notes, and 10 comment books including approximately 20 000 comments. Data suggested that the personal, physical, and sociocultural contexts (Falk & Dierking, 2000) contributed to visitor meaning meaning-making. The use of plastinated human cadavers within this exhibition raised ethical and moral questions and controversies about body procurement, use of human cadavers in display, representations of the bodies, and issues related to the sanctity of life. The tensions and issues identified by visitors demonstrated that messages (intended or unintended) located within Body Worlds were critically examined by visitors and called into question. Finally, data from this study suggested that an interdisciplinary approach to the presentation of science served to enhance accessibility for the viewer. This exhibition demonstrated that visitors responded positively and made personal connections when the arts, spirituality, edutainment, issues, and a combination of historical and contemporary museum practices were used to present science.

Hidden Attractors in Dynamical Systems. From Hidden Oscillations in Hilbert-Kolmogorov Aizerman, and Kalman Problems to Hidden Chaotic Attractor in Chua Circuits

NASA Astrophysics Data System (ADS)

Leonov, G. A.; Kuznetsov, N. V.

From a computational point of view, in nonlinear dynamical systems, attractors can be regarded as self-excited and hidden attractors. Self-excited attractors can be localized numerically by a standard computational procedure, in which after a transient process a trajectory, starting from a point of unstable manifold in a neighborhood of equilibrium, reaches a state of oscillation, therefore one can easily identify it. In contrast, for a hidden attractor, a basin of attraction does not intersect with small neighborhoods of equilibria. While classical attractors are self-excited, attractors can therefore be obtained numerically by the standard computational procedure. For localization of hidden attractors it is necessary to develop special procedures, since there are no similar transient processes leading to such attractors. At first, the problem of investigating hidden oscillations arose in the second part of Hilbert's 16th problem (1900). The first nontrivial results were obtained in Bautin's works, which were devoted to constructing nested limit cycles in quadratic systems, that showed the necessity of studying hidden oscillations for solving this problem. Later, the problem of analyzing hidden oscillations arose from engineering problems in automatic control. In the 50-60s of the last century, the investigations of widely known Markus-Yamabe's, Aizerman's, and Kalman's conjectures on absolute stability have led to the finding of hidden oscillations in automatic control systems with a unique stable stationary point. In 1961, Gubar revealed a gap in Kapranov's work on phase locked-loops (PLL) and showed the possibility of the existence of hidden oscillations in PLL. At the end of the last century, the difficulties in analyzing hidden oscillations arose in simulations of drilling systems and aircraft's control systems (anti-windup) which caused crashes. Further investigations on hidden oscillations were greatly encouraged by the present authors' discovery, in 2010 (for the first time), of chaotic hidden attractor in Chua's circuit. This survey is dedicated to efficient analytical-numerical methods for the study of hidden oscillations. Here, an attempt is made to reflect the current trends in the synthesis of analytical and numerical methods.

Deep Space Gateway Science Opportunities

NASA Astrophysics Data System (ADS)

Quincy, C. D.; Charles, J. B.; Hamill, D. L.; Sun, S. C.

2018-02-01

Life sciences see the Deep Space Gateway as an opportunity to investigate biological organisms in a unique environment that cannot be replicated in Earth-based labs or on LEO platforms. The needed capabilities must be built into the Gateway facility.

The perception of rational, goal-directed action in nonhuman primates.

PubMed

Wood, Justin N; Glynn, David D; Phillips, Brenda C; Hauser, Marc D

2007-09-07

Humans are capable of making inferences about other individuals' intentions and goals by evaluating their actions in relation to the constraints imposed by the environment. This capacity enables humans to go beyond the surface appearance of behavior to draw inferences about an individual's mental states. Presently unclear is whether this capacity is uniquely human or is shared with other animals. We show that cotton-top tamarins, rhesus macaques, and chimpanzees all make spontaneous inferences about a human experimenter's goal by attending to the environmental constraints that guide rational action. These findings rule out simple associative accounts of action perception and show that our capacity to infer rational, goal-directed action likely arose at least as far back as the New World monkeys, some 40 million years ago.

MY FATHER, MYSELF.

PubMed

Kogan, Ilany

2016-07-01

This essay presents material from the second analysis of an offspring of two Holocaust survivors, each of whom lost a child during the war. The first analysis (Kogan ) focused primarily on the patient's relationship with her mother. This second analysis revolves around the elaboration of the complex and painful father-daughter relationship, centering on the events surrounding the death of the patient's father. The discussion includes an exploration of the father's deferred action on account of his Holocaust trauma, which he passed on to the next generation; the break in the idealized paternal representation; and the daughter's identification with her father's disavowed aggressive aspects. It also examines some of the unique transference and countertransference problems that arose, mainly because patient and analyst belonged to the same traumatized large group. © 2016 The Psychoanalytic Quarterly, Inc.

Non-verbal communication between nurses and people with an intellectual disability: a review of the literature.

PubMed

Martin, Anne-Marie; O'Connor-Fenelon, Maureen; Lyons, Rosemary

2010-12-01

This article critically synthesizes current literature regarding communication between nurses and people with an intellectual disability who communicate non-verbally. The unique context of communication between the intellectual disability nurse and people with intellectual disability and the review aims and strategies are outlined. Communication as a concept is explored in depth. Communication between the intellectual disability nurse and the person with an intellectual disability is then comprehensively examined in light of existing literature. Issues including knowledge of the person with intellectual disability, mismatch of communication ability, and knowledge of communication arose as predominant themes. A critical review of the importance of communication in nursing practice follows. The paucity of literature relating to intellectual disability nursing and non-verbal communication clearly indicates a need for research.

Finding boundaries inside prison walls: case study of a terminally ill inmate.

PubMed

O'Connor, Mary-Frances

2004-01-01

The number of terminally ill prison inmates rises each year. Mental health professionals are uniquely prepared to provide therapy during the end-of-life process with their assessment, training, empathy, and communication skills. This case study examines the six-month therapy of one terminally ill inmate, using a client-centered approach. Drawing from existential therapy, the review of meaningful life events in the client's life clarifies current goals and the value of the current final stage of life. Ethical issues that arose are discussed, including pain management and compassionate release. Creative solutions to these ethical dilemmas were implemented through consideration of the overt and underlying goals of the inmate, the necessary rules and protocols of the prison, and in conjunction with professional codes of ethics.

Principal Components Analysis of Reflectance Spectra from the Mars Exploration Rover Opportunity

NASA Technical Reports Server (NTRS)

Mercer, C. M.; Cohen, B. A.

2010-01-01

In the summer of 2007 a global dust storm on Mars effectively disabled Opportunity's Miniature Thermal Emission Spectrometer (Mini-TES), the primary instrument used by the Athena Science Team to identify locally unique rocks on the Martian surface. The science team needs another way to distinguish interesting rocks from their surroundings on a tactical timescale. This study was designed to develop the ability to identify locally unique rocks on the Martian surface remotely using the Mars Exploration Rovers' Panoramica Camera (PanCam) instrument. Meridiani bedrock observed by Opportunity is largely characterized by sulfate-rich sandstones and hematite spherules. Additionally, loose fragments of bedrock and "cobbles" of foreign origin collet on the surface, some of which are interpreted as meteorites.

Building better connections: the National Library of Medicine and public health.

PubMed

Humphreys, Betsy L

2007-07-01

The paper describes the expansion of the public health programs and services of the National Library of Medicine (NLM) in the 1990s and provides the context in which NLM's public health outreach programs arose and exist today. Although NLM has always had collections and services relevant to public health, the US public health workforce made relatively little use of the library's information services and programs in the twentieth century. In the 1990s, intensified emphases on outreach to health professionals, building national information infrastructure, and promoting health data standards provided NLM with new opportunities to reach the public health community. A seminal conference cosponsored by NLM in 1995 produced an agenda for improving public health access to and use of advanced information technology and electronic information services. NLM actively pursued this agenda by developing new services and outreach programs and promoting public health informatics initiatives. Historical analysis is presented. NLM took advantage of a propitious environment to increase visibility and understanding of public health information challenges and opportunities. The library helped create partnerships that produced new information services, outreach initiatives, informatics innovations, and health data policies that benefit the public health workforce and the diverse populations it serves.

Learning about population-health through a community practice learning project: An evaluation study.

PubMed

Davenport, Maggie; Ooms, Ann; Marks-Maran, Di

2016-03-01

Increasing student nurse numbers requiring community placement learning opportunities has led to insufficient numbers of community nurses being available to support student nurses in the community. Although the study presented in the article is based in the UK this issue is reported widely in the literature across the globe. Universities in many countries have had to find innovative ways of providing community health learning opportunities for student nurses. This article reports on how one university in the UK has approached this challenge through students engaging in a population-based study in the community through group work. A research study was undertaken into this innovation which found that the student nurses engaged well with the project and with their groups and undertaking the project had positive value and impact on them and their understanding of population-health. Issues that arose for them largely focused on unequal participation in the group work by some with many participants perceiving that they had done more work on the group project and presentation than others in their group. However, working in this way was perceived to be a good learning experience for the majority of participants. Copyright © 2016 Elsevier Ltd. All rights reserved.

Unsettled teamwork: communication and learning in the operating theatres of an urban hospital.

PubMed

Bezemer, Jeff; Korkiakangas, Terhi; Weldon, Sharon-Marie; Kress, Gunther; Kneebone, Roger

2016-02-01

To explore the unsettling effects of increased mobility of nurses, surgeons and other healthcare professionals on communication and learning in the operating theatre. Increasingly, healthcare professionals step in and out of newly formed transient teams and work with colleagues they have not met before, unsettling previously relatively stable team work based on shared, local knowledge accumulated over significant periods of close collaboration. An ethnographic case study was conducted of the operating theatre department of a major teaching hospital in London. Video recordings were made of 20 operations, involving different teams. The recordings were systematically reviewed and coded. Instances where difficulties arose in the communication between scrub nurse and surgeons were identified and subjected to detailed, interactional analysis. Instrument requests frequently prompted clarification from the scrub nurse (e.g. 'Sorry, what did you want?'). Such requests were either followed by a relatively elaborate clarification, designed to maximize learning opportunities, or a by a relatively minimal clarification, designed to achieve the immediate task at hand. Significant variation exists in the degree of support given to scrub nurses requesting clarification. Some surgeons experience such requests as disruptions, while others treat them as opportunities to build shared knowledge. © 2015 John Wiley & Sons Ltd.

ENERGY MANAGEMENT INNOVATION IN THE US SKI INDUSTRY

EPA Science Inventory

Ski areas represent a unique opportunity to develop innovative energy management practices in an industrial setting. Through a unique synergy of onsite generation, preferably by renewable sources and innovative technologies, and the energy storage potential of exis...

International Students at Community Colleges: Challenges and Opportunities for This Unique Segment of U.S. Higher Education

ERIC Educational Resources Information Center

Jennings, Ross

2017-01-01

In unprecedented numbers, American community colleges are seeking to boost their recruitment and retention of international students. This chapter uncovers the challenges and opportunities based on successful experiences in community college efforts.

Visualising the body in art and medicine: a visual art course for medical students at King's College Hospital in 1999.

PubMed

Weller, Kathy

2002-11-01

For many centuries science and art have been studied as completely separate disciplines, and career paths likewise, have diverged. However, in recent years there has been a renewed cultural interest in art/science collaborations, coupled with the perception that a medical education which did not embrace the humanities 'tended to brutalize and dehumanize' (Weatherall, British Medical Journal 309 (1994) 1671-1672) future doctors. It was against this background of the growth of multi-disciplinary collaborative projects and a dissatisfaction with an 'incomplete' medical education, that an opportunity arose for a visual arts course to be set up at a London teaching hospital in 1999. The following dialogue sets out to explore the difficulties, the great joys and the emotions generated by a 'Special Study Module' created by both artists and clinicians.

Qualitative research on dementia in ethnically diverse communities: fieldwork challenges and opportunities.

PubMed

Shanley, Chris; Leone, Desiree; Santalucia, Yvonne; Adams, Jon; Ferrerosa-Rojas, Jorge Enrique; Kourouche, Fatima; Gava, Silvana; Wu, Ying

2013-05-01

Australia, like other ethnically diverse societies, needs to provide culturally appropriate health care to all its citizens. One way of facilitating this is to ensure that health services research adequately reflects the circumstances and needs of culturally and linguistically diverse (CALD) communities within the population. This article discusses the fieldwork phase of a qualitative research project on dementia caregiving in 4 CALD communities in south west Sydney, Australia. Rather than focusing on the study results-which have been published elsewhere-this article presents and discusses crucial fieldwork issues that arose in the conduct of the project, particularly regarding participant recruitment and facilitation of focus groups. In being transparent about some of the difficulties encountered and how these were managed, we offer suggestions for other researchers wanting to include CALD communities in a meaningful way in their research projects.

Advertising and Regulation during the New Deal Era, 1933-1941.

ERIC Educational Resources Information Center

Lanfranco, Leonard W.

As the "New Deal" era of the "Great Depression" promised relief from the publicly perceived failures of business and industry, a corresponding attitude of consumerism arose, aimed at "Big Business's" accomplice, advertising. Across the nation, national and local consumer protection organizations arose, and nonconsumer…

Surfactant Lipids at the Host-Environment Interface. Metabolic Sensors, Suppressors, and Effectors of Inflammatory Lung Disease.

PubMed

Fessler, Michael B; Summer, Ross S

2016-05-01

The lipid composition of pulmonary surfactant is unlike that of any other body fluid. This extracellular lipid reservoir is also uniquely susceptible by virtue of its direct and continuous exposure to environmental oxidants, inflammatory agents, and pathogens. Historically, the greatest attention has been focused on those biophysical features of surfactant that serve to reduce surface tension at the air-liquid interface. More recently, surfactant lipids have also been recognized as bioactive molecules that maintain immune quiescence in the lung but can also be remodeled by the inhaled environment into neolipids that mediate key roles in inflammation, immunity, and fibrosis. This review focuses on the roles in inflammatory and infectious lung disease of two classes of native surfactant lipids, glycerophospholipids and sterols, and their corresponding oxidized species, oxidized glycerophospholipids and oxysterols. We highlight evidence that surfactant composition is sensitive to circulating lipoproteins and that the lipid milieu of the alveolus should thus be recognized as susceptible to diet and common systemic metabolic disorders. We also discuss intriguing evidence suggesting that oxidized surfactant lipids may represent an evolutionary link between immunity and tissue homeostasis that arose in the primordial lung. Taken together, the emerging picture is one in which the unique environmental susceptibility of the lung, together with its unique extracellular lipid requirements, may have made this organ both an evolutionary hub and an engine for lipid-immune cross-talk.

A unique funding opportunity for public health in Texas.

PubMed

Schlenker, Thomas; Huber, Carol A

2015-01-01

In addition to the Affordable Care Act, states are more frequently turning to Medicaid waivers to achieve the "Triple Aim" goals of improving the experience of care, improving population health, and reducing per capita costs. These demonstration waivers provide opportunities to test innovative ways to finance and deliver care. Texas is currently implementing a waiver known as the Transformation and Quality Improvement Program. Its inclusion of public health agencies is a unique approach to a system typically limited to traditional providers. San Antonio Metropolitan Health District is one public health agency taking advantage of this new funding opportunity to implement 6 new or expanded programs targeting health issues of highest priority in this south Texas region. This article discusses the use of Medicaid waivers and the advantages and challenges of public health agency participation.

Life Sciences Research and Development Opportunities During Suborbital Space Flight

NASA Technical Reports Server (NTRS)

Davis, Jeffrey R.

2010-01-01

Suborbital space platforms provide a unique opportunity for Space Life Sciences in the next few years. The opportunities include: physiological characterization of the first few minutes of space flight; evaluation of a wide-variety of medical conditions during periods of hyper and hypo-gravity through physiological monitoring; and evaluation of new biomedical and environmental health technologies under hyper and hypo-gravity conditions

Explaining the increasing heritability of cognitive ability across development: a meta-analysis of longitudinal twin and adoption studies.

PubMed

Briley, Daniel A; Tucker-Drob, Elliot M

2013-09-01

Genes account for increasing proportions of variation in cognitive ability across development, but the mechanisms underlying these increases remain unclear. We conducted a meta-analysis of longitudinal behavioral genetic studies spanning infancy to adolescence. We identified relevant data from 16 articles with 11 unique samples containing a total of 11,500 twin and sibling pairs who were all reared together and measured at least twice between the ages of 6 months and 18 years. Longitudinal behavioral genetic models were used to estimate the extent to which early genetic influences on cognition were amplified over time and the extent to which innovative genetic influences arose with time. Results indicated that in early childhood, innovative genetic influences predominate but that innovation quickly diminishes, and amplified influences account for increasing heritability following age 8 years.

A strategy for complex dimer formation when biomimicry fails: total synthesis of ten coccinellid alkaloids.

PubMed

Sherwood, Trevor C; Trotta, Adam H; Snyder, Scott A

2014-07-09

Although dimeric natural products can often be synthesized in the laboratory by directly merging advanced monomers, these approaches sometimes fail, leading instead to non-natural architectures via incorrect unions. Such a situation arose during our studies of the coccinellid alkaloids, when attempts to directly dimerize Nature's presumed monomeric precursors in a putative biomimetic sequence afforded only a non-natural analogue through improper regiocontrol. Herein, we outline a unique strategy for dimer formation that obviates these difficulties, one which rapidly constructs the coccinellid dimers psylloborine A and isopsylloborine A through a terminating sequence of two reaction cascades that generate five bonds, five rings, and four stereocenters. In addition, a common synthetic intermediate is identified which allows for the rapid, asymmetric formal or complete total syntheses of eight monomeric members of the class.

Constructing a philosophy of chiropractic: evolving worldviews and premodern roots().

PubMed

Senzon, Simon A

2011-12-01

The philosophy of chiropractic can be framed as an attempt to correct the problems inherited from the Western Enlightenment. Its origins can be found in the long tradition of Western philosophy. The purpose of this article is to describe in a broad context chiropractic's roots in premodernity and establish the structural and hermeneutical differences between chiropractic's original philosophical ideas and those of premodern philosophers. The worldview or cultural mindset the philosophy arose from must be situated in the context of its time, the birth of the unique postmodern worldview, aperspectival consciousness, and the modern sense of self. This is accomplished by exploring several metatheories about the development of the self through history, with an emphasis on the premodern roots to the chiropractic terms; Universal Intelligence and Innate Intelligence. By contextualizing the philosophy of chiropractic in terms of a structural genealogy of the self and of ideas, a new approach to philosophy in chiropractic emerges. Without accounting for chiropractic's origins as a reflection of the unique time, place, and culture, in terms of the evolution of worldviews through history, any approach to construct or reconstruct a philosophy of chiropractic will potentially miss the seminal feature of chiropractic's emergence.

Unique Access to Learning

ERIC Educational Resources Information Center

Goble, Don

2009-01-01

This article describes the many learning opportunities that broadcast technology students at Ladue Horton Watkins High School in St. Louis, Missouri, experience because of their unique access to technology and methods of learning. Through scaffolding, stepladder techniques, and trial by fire, students learn to produce multiple television programs,…

Brain Metastasis: Unique Challenges and Open Opportunities

PubMed Central

Lowery, Frank J.; Yu, Dihua

2016-01-01

The metastasis of cancer to the central nervous system (CNS) remains a devastating clinical reality, carrying an estimated survival time of less than one year in spite of recent therapeutic breakthroughs for other disease contexts. Advances in brain metastasis research are hindered by a number of reasons, including its complicated nature and the difficulty of modeling metastatic cancer growth in the unique brain microenvironment. In this review, we will discuss the clinical challenge, and compare the values and limitations of the available models for brain metastasis research. Additionally, we will specifically address current knowledge on how brain metastases take advantage of the unique brain environment to benefit their own growth. Finally, we will explore the distinctive metabolic and nutrient characteristics of the brain; how these paradoxically represent barriers to establishment of brain metastasis, but also provide ample supplies for metastatic cells’ growth in the brain. We envision that multi-disciplinary innovative approaches will open opportunities for the field to make breakthroughs in tackling unique challenges of brain metastasis. PMID:27939792

Barriers, Opportunities, and Strategies for Urban Ecosystem Restoration: Lessons Learned from Restoration Managers in Rhode Island, U.S.A.

EPA Science Inventory

Urban ecosystem restoration can be especially difficult to accomplish because of complications like industrial pollutants, population density, infrastructure, and expense, however, the unique opportunities in urban settings, including the potential to provide benefits to many peo...

Integrating Opportunities: Applied Interdisciplinary Research in Undergraduate Geography and Geology Education

ERIC Educational Resources Information Center

Viertel, David C.; Burns, Diane M.

2012-01-01

Unique integrative learning approaches represent a fundamental opportunity for undergraduate students and faculty alike to combine interdisciplinary methods with applied spatial research. Geography and geoscience-related disciplines are particularly well-suited to adapt multiple methods within a holistic and reflective mentored research paradigm.…

Entrepreneurship: A Unique Opportunity for Higher Education. NCRCRD Policy Briefs

ERIC Educational Resources Information Center

Hamerlinck, John; Emery, Mary

2006-01-01

Entrepreneurship, both in commercial and social enterprise development, has become an essential component in sustaining thriving communities in the region. An expanded dedication to entrepreneurship can open up economic opportunities while simultaneously furthering the educational missions of colleges and universities by promoting a scholarship of…

A Unique Funding Opportunity for Public Health in Texas

PubMed Central

Schlenker, Thomas; Huber, Carol A.

2015-01-01

In addition to the Affordable Care Act, states are more frequently turning to Medicaid waivers to achieve the “Triple Aim” goals of improving the experience of care, improving population health, and reducing per capita costs. These demonstration waivers provide opportunities to test innovative ways to finance and deliver care. Texas is currently implementing a waiver known as the Transformation and Quality Improvement Program. Its inclusion of public health agencies is a unique approach to a system typically limited to traditional providers. San Antonio Metropolitan Health District is one public health agency taking advantage of this new funding opportunity to implement 6 new or expanded programs targeting health issues of highest priority in this south Texas region. This article discusses the use of Medicaid waivers and the advantages and challenges of public health agency participation. PMID:25423061

REU Programs at Field Research Stations Offer Unique Advantages that may Enhance Retention of Students in STEM Fields.

NASA Astrophysics Data System (ADS)

Kim, D. Y.; Marinelli, R. L.; Heidelberg, K., IV

2014-12-01

Studies have shown that undergraduate participation in research opportunities strengthens the retention of students in STEM fields. Increasing students' confidence levels in their scientific abilities, aiding in the development of their scientific identity, and strengthening their sense of belonging to a scientific community have been cited as important contributing factors. Research field stations offer unique advantages that amplify these benefits by challenging students to plan and work in the field, enhancing networking opportunities with multi-disciplinary professionals from numerous institutions and hierarchical levels, and creating a stronger sense of belonging and comradery within a science community. The USC Wrigley Institute for Environmental Studies' (WIES) Research Experiences for Undergraduates (REU) program is an 8-week program that begins on the main USC campus in Los Angeles and moves to a marine field station on Catalina Island during weeks 2-7, before returning to the mainland to complete the last week of the program. This unique model provides REU students with an opportunity to become integrated into faculty mentors' labs on the main campus, while exposing them to life as a researcher at a field station, both of which contribute significantly to the students' development as a scientist. Here, we present the WIES REU model and include a discussion of benefits and challenges to this unique infrastructure.

Charter Schools: Our Challenge, Our Opportunity. Spotlight--Montessori Diversity: Charter Schools.

ERIC Educational Resources Information Center

Kripalani, Lakshmi

2002-01-01

Asserts that charter schools provide unique and rich opportunities for Montessori educators to influence public education. Notes obstacles to establishing Montessori charter schools related to loss of funding for the local school district, the difficulty of Montessori teachers obtaining state certification, testing requirements to show student…

Marine Bioacoustics: Soundtracks for the Future

DTIC Science & Technology

2015-09-30

opportunity to work side by side with world experts using state-of-the- art tools and technologies. A secondary goal of the project is to provide a...we provide students with a unique opportunity to learn and work side by side with top scientists using state-of-the- art bioacoustic tools and

How I Spent My Summer Vacation: Amazing Opportunities for Teachers

ERIC Educational Resources Information Center

Curwood, Jen Scott

2008-01-01

From summer programs in archaeology or Russian to teaching abroad for a year or more, there are many opportunities available for teachers. This article describes unique programs in archeology, geology, astronomy, botany, and oceanography that are available as summer programs; master's programs in languages, administration, writing, and Teaching…

Considering Fees in Psychodynamic Psychotherapy: Opportunities for Residents

ERIC Educational Resources Information Center

Newman, Stewart S.

2005-01-01

OBJECTIVE: The topic of money is ubiquitous to psychodynamic therapy work, yet often neglected in residency training programs. Residency allows a unique opportunity to address issues pertaining to money and their impact on therapy. METHOD: Through the experience of the author, the need for a more explicit and systematic consideration within…

You've Been Served: Surviving a Deposition

ERIC Educational Resources Information Center

Wodarz, Nan

2010-01-01

School business managers are in the unique position of supervising the areas of the operation that present the greatest opportunities for legal issues to arise. New construction and renovation projects are strewn with legal land mines. The possibility of lawsuits hovers like a black cloud over personnel issues. Opportunities for transportation or…

Cholesteryl Ester Accumulation Induced by PTEN Loss and PI3K/AKT Activation Underlies Human Prostate Cancer Aggressiveness

PubMed Central

Yue, Shuhua; Li, Junjie; Lee, Seung-Young; Lee, Hyeon Jeong; Shao, Tian; Song, Bing; Cheng, Liang; Masterson, Timothy A.; Liu, Xiaoqi; Ratliff, Timothy L.; Cheng, Ji-Xin

2014-01-01

Summary Altered lipid metabolism is increasingly recognized as a signature of cancer cells. Enabled by label-free Raman spectromicroscopy, we performed quantitative analysis of lipogenesis at single cell level in human patient cancerous tissues. Our imaging data revealed an unexpected, aberrant accumulation of esterified cholesterol in lipid droplets of high-grade prostate cancer and metastases. Biochemical study showed that such cholesteryl ester accumulation was a consequence of loss of tumor suppressor PTEN and subsequent activation of PI3K/AKT pathway in prostate cancer cells. Furthermore, we found that such accumulation arose from significantly enhanced uptake of exogenous lipoproteins and required cholesterol esterification. Depletion of cholesteryl ester storage significantly reduced cancer proliferation, impaired cancer invasion capability, and suppressed tumor growth in mouse xenograft models with negligible toxicity. These findings open opportunities for diagnosing and treating prostate cancer by targeting the altered cholesterol metabolism. PMID:24606897

Heart-to-Heart

NASA Image and Video Library

2017-06-26

NASA didn’t miss a (heart)beat when the opportunity arose to study the cardiovascular systems of identical twin astronauts, one aboard the International Space Station and the other on Earth. Results from the Cardio Ox investigation, part of the research of the One Year Mission of astronaut Scott Kelly, may provide a better understanding of cardiovascular disease risk that astronauts encounter during and after long-duration spaceflight. Stuart Lee, the lead scientist for the Cardiovascular and Vision Laboratory at NASA’s Johnson Space Center, explains the importance of spaceflight weightlessness research on the cardiovascular system and how results could be used to create countermeasures, preventing potential health consequences for future space travelers as well as those of us on Earth. For more on ISS science, follow us on Twitter: @ISS_research or at https://twitter.com/ISS_Research or at: https://www.nasa.gov/mission_pages/station/research/index.html

Meteoroid, and debris special investigation group preliminary results: Size-frequency distribution and spatial density of large impact features on LDEF

NASA Technical Reports Server (NTRS)

See, Thomas H.; Hoerz, Friedrich; Zolensky, Michael E.; Allbrooks, Martha K.; Atkinson, Dale R.; Simon, Charles G.

1992-01-01

All craters greater than or equal to 500 microns and penetration holes greater than or equal to 300 microns in diameter on the entire Long Duration Exposure Facility (LDEF) were documented. Summarized here are the observations on the LDEF frame, which exposed aluminum 6061-T6 in 26 specific directions relative to LDEF's velocity vector. In addition, the opportunity arose to characterize the penetration holes in the A0178 thermal blankets, which pointed in nine directions. For each of the 26 directions, LDEF provided time-area products that approach those afforded by all previous space-retrieved materials combined. The objective here is to provide a factual database pertaining to the largest collisional events on the entire LDEF spacecraft with a minimum of interpretation. This database may serve to encourage and guide more interpretative efforts and modeling attempts.

Dutch citizens of Turkish origin who utilize healthcare services in Turkey: a qualitative study on motives and contextual factors.

PubMed

Şekercan, Aydın; Woudstra, Anke J; Peters, Ron J G; Lamkaddem, Majda; Akgün, Seval; Essink-Bot, Marie-Louise

2018-04-17

Dutch residents of Turkish origin frequently utilize healthcare in Turkey. To investigate their motives for doing so, we conducted a qualitative study among these healthcare users using semi-structured interviews. We complemented this with informal conversations with Turkish healthcare providers and observations at the registration offices and waiting rooms of outpatient clinics in several Turkish hospitals. Respondents believed their perceived needs for referral to specialist care and diagnostic assessments to quantify their health were not being met in the Netherlands. These mismatches in expectations of what constitutes "good care" led to dissatisfaction with Dutch primary care. Consequently, respondents utilized healthcare in Turkey if the opportunity arose, and were encouraged in this by their social networks. Establishing cross-border communication between healthcare providers is necessary, because there is currently no continuity of care for cross-border patients.

Rationally Irrational: The Case of Sexual Burglary.

PubMed

Pedneault, Amelie; Beauregard, Eric; Harris, Danielle A; Knight, Raymond A

2015-08-01

The present study investigated rationality in sexually motivated burglaries. Specifically, we analyzed the situational cues identified by sexual burglars in their target selection. The research project investigated 224 individual incidents of residential burglary with apparent sexual motivations. Situational characteristics of the incidents were recorded and analyzed using forward sequential regressions. Results indicated that most sexually motivated burglaries occurred in occupied residences with deficient physical guardianship, when the victim was alone. Violence, theft, penetration, and fetishism were found to be committed in circumstances that increased the benefits and lowered the risks. Results showed that sexual burglary is rational in nature-sexual burglars chose residences that were easy to break into. We found little support for the premise that such opportunities arose while carrying out regular burglaries. Instead, the data indicated that sexual burglars acted opportunistically on situational cues that are markedly dissimilar to those of regular burglars. © The Author(s) 2014.

Petrographic and Geochemical Characterization of Ore-Bearing Intrusions of the Noril'sk type, Siberia; With Discussion of Their Origin, Including Additional Datasets and Core Logs

USGS Publications Warehouse

Czamanske, Gerald K.

2002-01-01

The Noril'sk I, Talnakh, and Kharaelakh intrusions of the Noril'sk district host one of the outstanding metal concentrations in the world; contained Cu-Ni resources are comparable to the deposits at Sudbury, Ontario and the platinum group element (PGE) resource is second only to that of the Bushveld Complex. Our opportunity to cooperatively sample and study this district in Siberian Russia arose in 1990 through a memorandum of understanding between the U.S. Geological Survey and the former Ministry of Geology of the U.S.S.R. The world-class significance of these deposits and the possibility that understanding their geologic context, including construction of a credible 'ore-deposit model,' will lead to discovery of similar deposits elsewhere, inspired extensive studies of the ores, the mafic-intrusions which host them, and associated flood basalts.

Using EPSAT to analyze high power systems in the space environment. [Environment Power System Analysis Tool

NASA Technical Reports Server (NTRS)

Kuharski, Robert A.; Jongeward, Gary A.; Wilcox, Katherine G.; Rankin, Tom R.; Roche, James C.

1991-01-01

The authors review the Environment Power System Analysis Tool (EPSAT) design and demonstrate its capabilities by using it to address some questions that arose in designing the SPEAR III experiment. It is shown that that the rocket body cannot be driven to large positive voltages under the constraints of this experiment. Hence, attempts to measure the effects of a highly positive rocket body in the plasma environment should not be made in this experiment. It is determined that a hollow cathode will need to draw only about 50 mA to ground the rocket body. It is shown that a relatively small amount of gas needs to be released to induce a bulk breakdown near the rocket body, and this gas release should not discharge the sphere. Therefore, the experiment provides an excellent opportunity to study the neutralization of a differential charge.

Banning nuclear tests: cold feet in the Carter administration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kincade, W.H.

1978-11-01

Several factors are outlined as being responsible for preventing U.S. negotiators from reaching agreements on nuclear test limitations through the SALT II and the comprehensive test ban treaty (CTB) in spite of hopeful speculations early in the year. Major questions arose over whether the treaties could be ratified, a shift in emphasis from the verifiability of compliance to the reliability of U.S. stockpiles, doubts in the scientific community and virorous lobbying by opponents to constraining the military. Mr. Kincade feels that these factors have influenced Presidential decisiveness, causing the administration to lose public confidence when the purpose of actions towardmore » the Soviet Union and China was not explained. He further feels that by confusing the public and failing to capitalize on his leadership opportunities, the President has been unable to develop a public consensus in favor of nuclear arms control. 13 references.« less

Review of the use of magnetic concentrates in geochemical exploration

USGS Publications Warehouse

Overstreet, W.C.; Day, G.W.

1985-01-01

Magnetic concentrates recovered readily by hand magnet from alluvial sediments or panned concentrates have been used successfully in exploration as a geochemical sample medium for Cu, Zn, Co, Cr, Mo, Ni, V, Sn, and Be, particularly in arid environments where alluvial sediments may be contaminated by aeolian debris. Opportunity for this use arose recently as chemical and spectrographic techniques were developed to determine the abundances of a variety of trace elements in Fe-rich media. The use of analytical data from magnetic concentrates was introduced as one of several anomaly-enhancement techniques based on heavy minerals and intended to identify blind ore deposits. An extensive literature, reviewed here, on the relation of the chemical composition of the mineral magnetite, a main component of magnetic concentrates, to geologic conditions of origin, facilitates the interpretation of trace-element data in the context of association with ore deposits.

76 FR 23333 - Notice of Proposed Withdrawal Extension and Opportunity for Public Meeting; Wyoming

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-26

... Land Management, Interior. ACTION: Notice. SUMMARY: The United States Department of Agriculture (USDA... mining laws to protect unique topographic characteristics and recreation values of the Snowy Range Area... withdrawal extension is to continue to protect the unique topographic characteristics of the Snowy Range Area...

Postmodern View of Advisement in Higher Education.

ERIC Educational Resources Information Center

Stowe, Donald E.

1996-01-01

Examines implications of postmodernism, particularly chaos theory, for academic advising. Suggests that postmodernist advising acknowledges student angst and self-doubt, views each individual as a unique person and each advising session as a unique opportunity, views change as an ally rather than nemesis, and believes the advisor's impact is not…

Transforming Teaching Challenges into Learning Opportunities: Interdisciplinary Reflective Collaboration

ERIC Educational Resources Information Center

Callaghan, Ronel

2015-01-01

Teaching in higher education poses unique sets of challenges, especially for academics in the engineering, built sciences and information science education disciplines. This article focuses on how reflective collaboration can support academics in their quest to find unique solutions to challenges in different academic contexts. A reflective…

Catalysis by metal-organic frameworks: fundamentals and opportunities.

PubMed

Ranocchiari, Marco; van Bokhoven, Jeroen Anton

2011-04-14

Crystalline porous materials are extremely important for developing catalytic systems with high scientific and industrial impact. Metal-organic frameworks (MOFs) show unique potential that still has to be fully exploited. This perspective summarizes the properties of MOFs with the aim to understand what are possible approaches to catalysis with these materials. We categorize three classes of MOF catalysts: (1) those with active site on the framework, (2) those with encapsulated active species, and (3) those with active sites attached through post-synthetic modification. We identify the tunable porosity, the ability to fine tune the structure of the active site and its environment, the presence of multiple active sites, and the opportunity to synthesize structures in which key-lock bonding of substrates occurs as the characteristics that distinguish MOFs from other materials. We experience a unique opportunity to imagine and design heterogeneous catalysts, which might catalyze reactions previously thought impossible.

Consulting the community: public expectations and attitudes about genetics research

PubMed Central

Etchegary, Holly; Green, Jane; Dicks, Elizabeth; Pullman, Daryl; Street, Catherine; Parfrey, Patrick

2013-01-01

Genomic discoveries and technologies promise numerous opportunities for improving health. Key to these potential health improvements, however, are health-care consumers' understanding and acceptance of these new developments. We identified community groups and invited them to a public information-consultation session in order to explore public awareness, perception and expectations about genetics and genomics research. One hundred and four members of seven community groups in Newfoundland, Canada took part in the community sessions. Content analysis of participant comments revealed they were largely hopeful about genetics research in its capacity to improve health; however, they did not accept such research uncritically. Complex issues arose during the community consultations, including the place of genetics in primary care, the value of genetics for personal health, and concerns about access to and uses of genetic information. Participants unequivocally endorsed the value of public engagement with these issues. The rapid pace of discoveries in genomics research offers exciting opportunities to improve population health. However, public support will be crucial to realize health improvements. Our findings suggest that regular, transparent dialog between researchers and the public could allow a greater understanding of the research process, as well as assist in the design of efficient and effective genetic health services, informed by the public that will use them. PMID:23591403

Past evolutionary tradeoffs represent opportunities for crop genetic improvement and increased human lifespan.

PubMed

Denison, R Ford

2011-03-01

The repeated evolution of complex adaptations - crop mimicry by weeds, for example, or CO2-concentrating C4 photosynthesis - shows the power of natural selection to solve difficult problems that limited fitness in past environments. The sophistication of natural selection's innovations contrasts with the relatively simple changes (e.g., increasing the expression of existing genes) readily achievable by today's biotechnology. Mutants with greater expression of these genes arose repeatedly over the course of evolution, so their present rarity indicates rejection by natural selection. Similarly, medical interventions that simply up- or down-regulate existing physiological mechanisms presumably recreate phenotypes also rejected by past natural selection. Some tradeoffs that constrained past natural selection still apply, such as those resulting from conservation of matter. But tradeoffs between present human goals and individual fitness in past environments may represent fairly easy opportunities to achieve our goals by reversing some effects of past selection. This point is illustrated with three examples, based on tradeoffs between (i) individual-plant fitness versus whole-crop performance, (ii) the fitness of symbionts (rhizobia) versus that of their legume hosts, and (iii) human fertility versus longevity in the context of environmental cues, such as consumption of 'famine foods', that predict trends in population size.

Perception of interprofessional conflicts and interprofessional education by doctors and nurses.

PubMed

Lee, Young Hee; Ahn, Ducksun; Moon, Jooyoung; Han, KuemSun

2014-12-01

This study aimed to collect information that is needed to develop interprofessional education curricula by examining the current status of interprofessional conflicts and the demand for interprofessional education. A total of 95 doctors and 92 nurses in three university hospitals in Seoul responded to a survey that comprised questions on past experience with interprofessional conflicts, the causes and solutions of such conflicts, past experience with interprofessional education, and the demand for interprofessional education. We found that 86% of doctors and 62.6% of nurses had no interprofessional education experience. Most of them learned about the work of other health professions naturally through work experience, and many had experienced at least one interprofessional conflict. For doctors, the most popular method of resolving interprofessional conflicts was to let the event pass; for nurses, it was to inform the department head. Further, 41.5% of doctors and 56.7% of nurses expressed no knowledge of an official system for resolving interprofessional conflicts within the hospital, and 62.8% of doctors and 78.3% of nurses stated that they would participate in interprofessional education if the opportunity arose. In Korean hospital organizations, many doctors and nurses have experienced conflicts with other health professionals. By developing an appropriate curriculum and educational training system, the opportunities for health professionals to receive interprofessional education should expand.

Machine Learning Technologies and Their Applications for Science and Engineering Domains Workshop -- Summary Report

NASA Technical Reports Server (NTRS)

Ambur, Manjula; Schwartz, Katherine G.; Mavris, Dimitri N.

2016-01-01

The fields of machine learning and big data analytics have made significant advances in recent years, which has created an environment where cross-fertilization of methods and collaborations can achieve previously unattainable outcomes. The Comprehensive Digital Transformation (CDT) Machine Learning and Big Data Analytics team planned a workshop at NASA Langley in August 2016 to unite leading experts the field of machine learning and NASA scientists and engineers. The primary goal for this workshop was to assess the state-of-the-art in this field, introduce these leading experts to the aerospace and science subject matter experts, and develop opportunities for collaboration. The workshop was held over a three day-period with lectures from 15 leading experts followed by significant interactive discussions. This report provides an overview of the 15 invited lectures and a summary of the key discussion topics that arose during both formal and informal discussion sections. Four key workshop themes were identified after the closure of the workshop and are also highlighted in the report. Furthermore, several workshop attendees provided their feedback on how they are already utilizing machine learning algorithms to advance their research, new methods they learned about during the workshop, and collaboration opportunities they identified during the workshop.

Evolutionary origin and functional divergence of totipotent cell homeobox genes in eutherian mammals.

PubMed

Maeso, Ignacio; Dunwell, Thomas L; Wyatt, Chris D R; Marlétaz, Ferdinand; Vető, Borbála; Bernal, Juan A; Quah, Shan; Irimia, Manuel; Holland, Peter W H

2016-06-13

A central goal of evolutionary biology is to link genomic change to phenotypic evolution. The origin of new transcription factors is a special case of genomic evolution since it brings opportunities for novel regulatory interactions and potentially the emergence of new biological properties. We demonstrate that a group of four homeobox gene families (Argfx, Leutx, Dprx, Tprx), plus a gene newly described here (Pargfx), arose by tandem gene duplication from the retinal-expressed Crx gene, followed by asymmetric sequence evolution. We show these genes arose as part of repeated gene gain and loss events on a dynamic chromosomal region in the stem lineage of placental mammals, on the forerunner of human chromosome 19. The human orthologues of these genes are expressed specifically in early embryo totipotent cells, peaking from 8-cell to morula, prior to cell fate restrictions; cow orthologues have similar expression. To examine biological roles, we used ectopic gene expression in cultured human cells followed by high-throughput RNA-seq and uncovered extensive transcriptional remodelling driven by three of the genes. Comparison to transcriptional profiles of early human embryos suggest roles in activating and repressing a set of developmentally-important genes that spike at 8-cell to morula, rather than a general role in genome activation. We conclude that a dynamic chromosome region spawned a set of evolutionarily new homeobox genes, the ETCHbox genes, specifically in eutherian mammals. After these genes diverged from the parental Crx gene, we argue they were recruited for roles in the preimplantation embryo including activation of genes at the 8-cell stage and repression after morula. We propose these new homeobox gene roles permitted fine-tuning of cell fate decisions necessary for specification and function of embryonic and extra-embryonic tissues utilised in mammalian development and pregnancy.

Co-Option and De Novo Gene Evolution Underlie Molluscan Shell Diversity

PubMed Central

Aguilera, Felipe; McDougall, Carmel

2017-01-01

Abstract Molluscs fabricate shells of incredible diversity and complexity by localized secretions from the dorsal epithelium of the mantle. Although distantly related molluscs express remarkably different secreted gene products, it remains unclear if the evolution of shell structure and pattern is underpinned by the differential co-option of conserved genes or the integration of lineage-specific genes into the mantle regulatory program. To address this, we compare the mantle transcriptomes of 11 bivalves and gastropods of varying relatedness. We find that each species, including four Pinctada (pearl oyster) species that diverged within the last 20 Ma, expresses a unique mantle secretome. Lineage- or species-specific genes comprise a large proportion of each species’ mantle secretome. A majority of these secreted proteins have unique domain architectures that include repetitive, low complexity domains (RLCDs), which evolve rapidly, and have a proclivity to expand, contract and rearrange in the genome. There are also a large number of secretome genes expressed in the mantle that arose before the origin of gastropods and bivalves. Each species expresses a unique set of these more ancient genes consistent with their independent co-option into these mantle gene regulatory networks. From this analysis, we infer lineage-specific secretomes underlie shell diversity, and include both rapidly evolving RLCD-containing proteins, and the continual recruitment and loss of both ancient and recently evolved genes into the periphery of the regulatory network controlling gene expression in the mantle epithelium. PMID:28053006

Forensic archaeology and anthropology : An Australian perspective.

PubMed

Oakley, Kate

2005-09-01

Forensic archaeology is an extremely powerful investigative discipline and, in combination with forensic anthropology, can provide a wealth of evidentiary information to police investigators and the forensic community. The re-emergence of forensic archaeology and anthropology within Australia relies on its diversification and cooperation with established forensic medical organizations, law enforcement forensic service divisions, and national forensic boards. This presents a unique opportunity to develop a new multidisciplinary approach to forensic archaeology/anthropology within Australia as we hold a unique set of environmental, social, and cultural conditions that diverge from overseas models and require different methodological approaches. In the current world political climate, more forensic techniques are being applied at scenes of mass disasters, genocide, and terrorism. This provides Australian forensic archaeology/anthropology with a unique opportunity to develop multidisciplinary models with contributions from psychological profiling, ballistics, sociopolitics, cultural anthropology, mortuary technicians, post-blast analysis, fire analysis, and other disciplines from the world of forensic science.

Geology Museum-Based Learning in Soil Science Education

ERIC Educational Resources Information Center

Mikhailova, E. A.; Tennant, C. H.; Post, C. J.; Cicimurri, C.; Cicimurri, D.

2013-01-01

Museums provide unique learning opportunities in soil science. The Bob Campbell Geology Museum in Clemson, SC, features an exhibit of minerals and rocks common in the state and in its geologic history. We developed a hands-on laboratory exercise utilizing an exhibit that gives college students an opportunity to visualize regional minerals and…

Fueling Chemical Engineering Concepts with Biodiesel Production: A Professional Development Experience for High School Pre-Service Teachers

ERIC Educational Resources Information Center

Gupta, Anju

2015-01-01

This one-day workshop for pre-service teachers was aimed at implementing a uniquely designed and ready-to-implement chemical engineering curriculum in high school coursework. This educational and professional development opportunity introduced: 1) chemical engineering curriculum and career opportunities, 2) basic industrial processes and flow…

Social media as a platform for science and health engagement: challenges and opportunities.

PubMed

Dixon, Graham

2016-01-01

Social media has become a major platform for debates on science and health. This commentary argues that while social media can present challenges to communicating important health matters, it can also provide health experts a unique opportunity to engage with and build trust among members of the public.

Approaches to measuring quality of the wilderness experience

Treesearch

William T. Borrie; Robert M. Birzell

2001-01-01

Wilderness is a special place that provides opportunity for unique and profound experiences. An essential task for the maintenance of these recreational opportunities is the definition and monitoring of experience quality. Four approaches to the measurement of the wilderness experience have developed in over 30 years of research: satisfaction approaches (which focus on...

Guidelines for Becoming a Teacher Leader in Rural Special Education

ERIC Educational Resources Information Center

Collins, Belva C.; Leahy, Maria Marsella; Ault, Melinda Jones

2017-01-01

Special education teachers have a unique set of skills and opportunities to become leaders in the field of education. Some rural special education teachers, however, may not see themselves as potential leaders or believe they have opportunities to be leaders. This article provides guidelines for rural special education teachers to consider in…

A Framework for Bilingual School Consultation to Facilitate Multitier Systems of Support for English Language Learners

ERIC Educational Resources Information Center

Harris, Bryn; Sullivan, Amanda L.

2017-01-01

Bilingual students comprise a substantial and growing proportion of U.S. school enrollment and often experience unsatisfactory school outcomes attributed to limited opportunities to learn. Bilingual consultants have the unique opportunity to shape school psychological services and general education supports for all bilingual students by working…

Pathways, Networks, and Systems: Theory and Experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joseph H. Nadeau; John D. Lambris

2004-10-30

The international conference provided a unique opportunity for theoreticians and experimenters to exchange ideas, strategies, problems, challenges, language and opportunities in both formal and informal settings. This dialog is an important step towards developing a deep and effective integration of theory and experiments in studies of systems biology in humans and model organisms.

Molecular Evolution and Functional Diversification of Replication Protein A1 in Plants

PubMed Central

Aklilu, Behailu B.; Culligan, Kevin M.

2016-01-01

Replication protein A (RPA) is a heterotrimeric, single-stranded DNA binding complex required for eukaryotic DNA replication, repair, and recombination. RPA is composed of three subunits, RPA1, RPA2, and RPA3. In contrast to single RPA subunit genes generally found in animals and yeast, plants encode multiple paralogs of RPA subunits, suggesting subfunctionalization. Genetic analysis demonstrates that five Arabidopsis thaliana RPA1 paralogs (RPA1A to RPA1E) have unique and overlapping functions in DNA replication, repair, and meiosis. We hypothesize here that RPA1 subfunctionalities will be reflected in major structural and sequence differences among the paralogs. To address this, we analyzed amino acid and nucleotide sequences of RPA1 paralogs from 25 complete genomes representing a wide spectrum of plants and unicellular green algae. We find here that the plant RPA1 gene family is divided into three general groups termed RPA1A, RPA1B, and RPA1C, which likely arose from two progenitor groups in unicellular green algae. In the family Brassicaceae the RPA1B and RPA1C groups have further expanded to include two unique sub-functional paralogs RPA1D and RPA1E, respectively. In addition, RPA1 groups have unique domains, motifs, cis-elements, gene expression profiles, and pattern of conservation that are consistent with proposed functions in monocot and dicot species, including a novel C-terminal zinc-finger domain found only in plant RPA1C-like sequences. These results allow for improved prediction of RPA1 subunit functions in newly sequenced plant genomes, and potentially provide a unique molecular tool to improve classification of Brassicaceae species. PMID:26858742

Overlap of heritable influences between cannabis use disorder, frequency of use and opportunity to use cannabis: trivariate twin modelling and implications for genetic design.

PubMed

Hines, Lindsey A; Morley, Katherine I; Rijsdijk, Fruhling; Strang, John; Agrawal, Arpana; Nelson, Elliot C; Statham, Dixie; Martin, Nicholas G; Lynskey, Michael T

2018-03-13

The genetic component of Cannabis Use Disorder may overlap with influences acting more generally on early stages of cannabis use. This paper aims to determine the extent to which genetic influences on the development of cannabis abuse/dependence are correlated with those acting on the opportunity to use cannabis and frequency of use. A cross-sectional study of 3303 Australian twins, measuring age of onset of cannabis use opportunity, lifetime frequency of cannabis use, and lifetime DSM-IV cannabis abuse/dependence. A trivariate Cholesky decomposition estimated additive genetic (A), shared environment (C) and unique environment (E) contributions to the opportunity to use cannabis, the frequency of cannabis use, cannabis abuse/dependence, and the extent of overlap between genetic and environmental factors associated with each phenotype. Variance components estimates were A = 0.64 [95% confidence interval (CI) 0.58-0.70] and E = 0.36 (95% CI 0.29-0.42) for age of opportunity to use cannabis, A = 0.74 (95% CI 0.66-0.80) and E = 0.26 (95% CI 0.20-0.34) for cannabis use frequency, and A = 0.78 (95% CI 0.65-0.88) and E = 0.22 (95% CI 0.12-0.35) for cannabis abuse/dependence. Opportunity shares 45% of genetic influences with the frequency of use, and only 17% of additive genetic influences are unique to abuse/dependence from those acting on opportunity and frequency. There are significant genetic contributions to lifetime cannabis abuse/dependence, but a large proportion of this overlaps with influences acting on opportunity and frequency of use. Individuals without drug use opportunity are uninformative, and studies of drug use disorders must incorporate individual exposure to accurately identify aetiology.

Redesigned PDC bit solves low hydraulic hp problems

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-06-01

A new PDC bit design was created to solve a problem a drilling contractor had due to hydraulic horsepower limitations on rigs used in a particular geographical area. The new bit design, which arose from a formal alliance between Exeter Drilling Co. and Hughes Christensen Co. has greatly improved bit cleaning and overall drilling efficiency in applications where only low hydraulic hp is available. The new design has been run successfully in the Denver-Julesburg (D-J) basin of Colorado. The development was described in detail in paper IADC/SPE 35109, ``Unique PDC bit configuration dramatically improves hole cleaning, drilling efficiency in lowmore » hydraulic applications,`` presented by G.J. Hertzler III, Exeter Drilling Co. and J.T. Wankier, Hughes Christensen Co., at the 1996 IADC/SPE Drilling Conference, New Orleans, La., March 12--15. This article is an abstract of that paper, which contains significantly more technical data.« less

unmarked: An R package for fitting hierarchical models of wildlife occurrence and abundance

USGS Publications Warehouse

Fiske, Ian J.; Chandler, Richard B.

2011-01-01

Ecological research uses data collection techniques that are prone to substantial and unique types of measurement error to address scientific questions about species abundance and distribution. These data collection schemes include a number of survey methods in which unmarked individuals are counted, or determined to be present, at spatially- referenced sites. Examples include site occupancy sampling, repeated counts, distance sampling, removal sampling, and double observer sampling. To appropriately analyze these data, hierarchical models have been developed to separately model explanatory variables of both a latent abundance or occurrence process and a conditional detection process. Because these models have a straightforward interpretation paralleling mechanisms under which the data arose, they have recently gained immense popularity. The common hierarchical structure of these models is well-suited for a unified modeling interface. The R package unmarked provides such a unified modeling framework, including tools for data exploration, model fitting, model criticism, post-hoc analysis, and model comparison.

Digital Optical Control System

NASA Astrophysics Data System (ADS)

Jordan, David H.; Tipton, Charles A.; Christmann, Charles E.; Hochhausler, Nils P.

1988-09-01

We describe the digital optical control system (DOGS), a state-of-the-art controller for electrical feedback in an optical system. The need for a versatile optical controller arose from a number of unique experiments being performed by the Air Force Weapons Laboratory. These experiments use similar detectors and actuator-controlled mirrors, but the control requirements vary greatly. The experiments have in common a requirement for parallel control systems. The DOGS satisfies these needs by allowing several control systems to occupy a single chassis with one master controller. The architecture was designed to allow upward compatibility with future configurations. Combinations of off-the-shelf and custom boards are configured to meet the requirements of each experiment. The configuration described here was used to control piston error to X/80 at a wavelength of 0.51 Am. A peak sample rate of 8 kHz, yielding a closed loop bandwidth of 800 Hz, was achieved.

Bioenergetic Constraints on the Evolution of Complex Life

PubMed Central

Lane, Nick

2014-01-01

All morphologically complex life on Earth, beyond the level of cyanobacteria, is eukaryotic. All eukaryotes share a common ancestor that was already a complex cell. Despite their biochemical virtuosity, prokaryotes show little tendency to evolve eukaryotic traits or large genomes. Here I argue that prokaryotes are constrained by their membrane bioenergetics, for fundamental reasons relating to the origin of life. Eukaryotes arose in a rare endosymbiosis between two prokaryotes, which broke the energetic constraints on prokaryotes and gave rise to mitochondria. Loss of almost all mitochondrial genes produced an extreme genomic asymmetry, in which tiny mitochondrial genomes support, energetically, a massive nuclear genome, giving eukaryotes three to five orders of magnitude more energy per gene than prokaryotes. The requirement for endosymbiosis radically altered selection on eukaryotes, potentially explaining the evolution of unique traits, including the nucleus, sex, two sexes, speciation, and aging. PMID:24789818

Complex Cloud and Radiative Processes Unfolding at the Earth's Terminator: A Unique Perspective from the Proposed Deep Space Gateway

NASA Astrophysics Data System (ADS)

Davis, A. B.; Marshak, A.

2018-02-01

The Deep Space Gateway offers a unique vantage for Earth observation using reflected sunlight: day/night or night/day terminators slowly marching across the disc. It's an opportunity to improve our understanding of clouds at that key moment in their daily cycle.

78 FR 13006 - New Intelligent Mail Package Barcode Standards To Enhance Package Visibility; Opportunity for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-26

...The Postal Service is exploring the advisability of requiring the use of Intelligent Mail[supreg] package barcodes (IMpb) or unique tracking Intelligent Mail barcodes (IMbTM) on all commercial parcels, and providing support to mailers to assure their ability to apply unique tracking barcodes to all commercial parcels.

Rethink, Reimagine, Reinvent: The Reggio Emilia Approach to Incorporating Reclaimed Materials in Children's Artworks

ERIC Educational Resources Information Center

Eckhoff, Angela; Spearman, Mindy

2009-01-01

Introducing reclaimed materials into the art classroom provides students with unique opportunities to connect ordinary, discarded objects with unique, personal artistic creations. In an effort to better understand this connection, this article explores existing pedagogical precedents that support the role of the inclusion of reclaimed materials in…

Onset Of Opportunity To Use Cannabis And Progression From Opportunity To Dependence: Are Influences Consistent Across Transitions?

PubMed Central

Hines, Lindsey A.; Morley, Katherine I.; Strang, John; Agrawal, Arpana; Nelson, Elliot C.; Statham, Dixie; Martin, Nicholas G.; Lynskey, Michael T.

2016-01-01

Background There is a developing body of research looking at cannabis use opportunity, but little research examining timing of opportunity to use cannabis. Aims Identify factors associated with 1) earlier opportunity to use cannabis and 2) faster progression from opportunity to cannabis dependence. Method Cross-sectional study of 3824 Australian twins and siblings, measuring age of onset of cannabis use opportunity and DSM-IV cannabis dependence. Survival analysis identified factors associated with faster progression to opportunity or dependence. Results Factors associated with both speed of progression to opportunity and dependence were conduct disorder (opportunity HR 5.57, 95%CI 1.52–20.47; dependence HR 2.49, 95%CI 1.91–3.25), parental drug problems (opportunity HR 7.29, 95%CI 1.74–30.62; dependence HR 3.30, 95%CI 1.63–6.69), weekly tobacco use (opportunity HR 8.57, 95%CI 3.93–18.68; dependence HR 2.76, 95% CI 2.10–3.64), and female gender (opportunity HR 0.69, 95%CI 0.64–0.75; dependence HR 0.44, 95%CI 0.34–0.55). Frequent childhood religious attendance (HR 0.74, 95%CI 0.68–0.80), parental conflict (HR 1.09, 95%CI 1.00–1.18), parental alcohol problems (HR 1.19, 95%CI 1.08–1.30) and childhood sexual abuse (HR 1.17, 95%CI 1.01–1.34) were uniquely associated with transition to opportunity. Depressive episode (HR 1.44, 95%CI 1.12–1.85), tobacco dependence (HR 1.36, 95%CI 1.04 – 1.78), alcohol dependence (HR 2.64, 95%CI 1.53–4.58), other drug use (HR 2.10, 95%CI 1.64–2.69) and other drug dependence (HR 2.75, 95%CI 1.70–4.43) were uniquely associated with progression to dependence. Conclusion The profile of factors associated with opportunity to use cannabis and dependence only partially overlaps, suggesting targeting of interventions may benefit from being tailored to the stages of drug use. PMID:26811121

Battle for the mind: World War 1 and the birth of military psychiatry.

PubMed

Jones, Edgar; Wessely, Simon

2014-11-08

The 100th anniversary of the outbreak of World War 1 could be viewed as a tempting opportunity to acknowledge the origins of military psychiatry and the start of a journey from psychological ignorance to enlightenment. However, the psychiatric legacy of the war is ambiguous. During World War 1, a new disorder (shellshock) and a new treatment (forward psychiatry) were introduced, but the former should not be thought of as the first recognition of what is now called post-traumatic stress disorder and the latter did not offer the solution to the management of psychiatric casualties, as was subsequently claimed. For this Series paper, we researched contemporary publications, classified military reports, and casualty returns to reassess the conventional narrative about the effect of shellshock on psychiatric practice. We conclude that the expression of distress by soldiers was culturally mediated and that patients with postcombat syndromes presented with symptom clusters and causal interpretations that engaged the attention of doctors but also resonated with popular health concerns. Likewise, claims for the efficacy of forward psychiatry were inflated. The vigorous debates that arose in response to controversy about the nature of psychiatric disorders and the discussions about how these disorders should be managed remain relevant to the trauma experienced by military personnel who have served in Iraq and Afghanistan. The psychiatric history of World War 1 should be thought of as an opportunity for commemoration and in terms of its contemporary relevance-not as an opportunity for self-congratulation. Copyright © 2014 Elsevier Ltd. All rights reserved.

Equal Opportunities for Spanish-Speaking People. Hearings Before the Civil Rights and Constitutional Rights Subcommittee of the Committee on the Judiciary, House of Representatives, Ninety-third Congress, First Session on the Role of the Cabinet Committee on Opportunities for Spanish-Speaking People in Providing Equal Opportunities for Spanish-Speaking People (July 11 and 19, 1973).

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. House Committee on the Judiciary.

The statutory purpose of the Cabinet Committee on Opportunities for the Spanish Speaking People, established in December 1969, is twofold: (1) to assure that Federal programs are reaching all Spanish-speaking and Spanish-surnamed Americans, and (2) to seek out new programs which may be necessary to handle problems unique to such persons. On July…

Developing a UAS Program for Electric Utilities

NASA Astrophysics Data System (ADS)

Keltgen, James

New innovations and technologies using unmanned aerial systems (UAS), or drones, have created unique opportunities for commercial applications. Electric utilities, likewise, realize the benefits of using UAS as a tool in electric utility operations. Although the opportunities exist, establishing a UAS program for electric utilities is largely an endeavor of trial and error or research and development with no clear path defined on how to establish a UAS program. By reviewing UAS use case examples and integrating lessons learned with Federal Aviation Administration (FAA) regulations, UAS best practices, unique electric utility values, legal and insurance perspectives, equipment selection, and thoughtful planning and preparation; a solution model is developed to establish a UAS program for electric utilities.

The potential of space exploration for education

NASA Technical Reports Server (NTRS)

Shair, Fredrick H.

1993-01-01

Space exploration and observations from space offer unique opportunities with respect to education. Recent technical advances have significantly increased the width and sensitivity of the electromagnetic spectrum window through which we are able to 'see' the universe. Observations from space have forced a realization that the earth is a beautiful, complex, and interconnected system. Space astronomy and the remote sensing of objects throughout our solar system have the potential of providing unique educational opportunities. Modern technologies have significantly reduced the cost of collecting, transmitting and processing data. Consequently, we are entering an age where it is possible to open up the process of discovery to almost everyone - and especially to young people throughout the world.

Mixer-Ejector Wind Turbine: Breakthrough High Efficiency Shrouded Wind Turbine

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2010-02-22

Broad Funding Opportunity Announcement Project: FloDesign Wind Turbine’s innovative wind turbine, inspired by the design of jet engines, could deliver 300% more power than existing wind turbines of the same rotor diameter by extracting more energy over a larger area. FloDesign Wind Turbine’s unique shrouded design expands the wind capture area, and the mixing vortex downstream allows more energy to flow through the rotor without stalling the turbine. The unique rotor and shrouded design also provide significant opportunity for mass production and simplified assembly, enabling mid-scale turbines (approximately 100 kW) to produce power at a cost that is comparable tomore » larger-scale conventional turbines.« less

Reverse Inclusion: Providing Peer Social Interaction Opportunities to Students Placed in Self-Contained Special Education Classrooms

ERIC Educational Resources Information Center

Schoger, Kimberly D.

2006-01-01

The social and academic benefits of inclusion for students with disabilities have been well researched and well documented. Unfortunately, inclusion opportunities are limited by lack of qualified staff, logistics, scheduling and other difficulties encountered when attempting to meet students' unique needs in the general education setting. As a…

Take To the Streets: Guide To Planning Outdoor, Public Exhibits.

ERIC Educational Resources Information Center

Cutting, Jennifer McGregor; And Others

Placing exhibits in public places provides a unique opportunity to reach a broad non-museum-going audience. It offers marketing and publicity opportunities as well as the potential to develop relationships with agencies and individuals who are stakeholders in the public site. The purpose of this guidebook is to describe the steps in creating an…

The American Recovery and Reinvestment Act: Opportunities for High School Improvement

ERIC Educational Resources Information Center

Rutenberg, David

2009-01-01

The American Recovery and Reinvestment Act (ARRA) creates a unique opportunity for states, districts, and high schools to work in concert on behalf of high school students. Generally, American Recovery and Reinvestment Act funds are not intended to create new programs; rather, the majority of the funds are intended to fill gaps in existing…

The Creation and Implementation of a Dream: Lessons Learned from a Unique Case Study

ERIC Educational Resources Information Center

Wheat, Kevin

2017-01-01

Many educational leaders dream of the opportunity to begin a new school. New schools provide opportunities for innovation, change, and creativity, which most educators believe is needed to improve current middle school practice. This study follows the process of planning for and opening a new and innovative middle school program designed to offer…

Latino Immigration, Education, and Opportunity

ERIC Educational Resources Information Center

Jimenez, Rosa M.

2012-01-01

Immigration is often framed as a problem, yet it is also a time of remarkable opportunity. While immigrants come to the United States from all over the world, the author focuses on the unique and urgent issues related to Latino immigration. Immigrant Latinos have changed the face of America and U.S. schools. Approximately one in five K-12 students…

Teachers' Perspectives of Professional Development for Effecting Change in Maori Medium Classrooms: A Mathematics Experience

ERIC Educational Resources Information Center

Hawera, Ngawera; Taylor, Merilyn

2011-01-01

In 2010 twenty-three Maori medium schools were given the opportunity for professional development with the Draft Nga Whanaketanga Rumake Maori: Pangarau (NWRM) (National Standards Maori Medium: Mathematics. The study provided a unique opportunity to listen to teachers' views about their professional development as they sought to implement national…

Location, Location, Location: Does Place Provide the Opportunity for Differentiation for Universities?

ERIC Educational Resources Information Center

Winter, Emma; Thompson-Whiteside, Helen

2017-01-01

The fiercely competitive HE market has led HEIs to invest significant resources in building a distinct identity. An HEI's location forms an inherent part of its identity and the uniqueness of location offers an opportunity to differentiate. However there has been limited examination of how location is used by HEIs and little consideration of how…

Opportunity and development of bio-based composites

Treesearch

Zhiyong Cai; Jerrold E. Winandy

2005-01-01

Our forests are a naturally renewable resource that has been used as a principal source of bio-energy and building materials for centuries. The rapid growth of world population has now resulted in substantial increases in demand and in consumption of all raw materials. This now provides a unique opportunity of developing new bio-based composites. The 100-year history...

Supporting the Literacy Development of Students Who Are Deaf/Hard of Hearing in Inclusive Classrooms

ERIC Educational Resources Information Center

Dostal, Hannah; Gabriel, Rachael; Weir, Joan

2017-01-01

Students who are deaf or hard of hearing present unique opportunities and challenges for literacy instruction in mainstream classrooms. By addressing the specific needs of this diverse student community, teachers are given the chance to sharpen instruction and create learning opportunities for the entire class. The authors discuss two…

mtDNA control-region sequence variation suggests multiple independent origins of an "Asian-specific" 9-bp deletion in sub-Saharan Africans.

PubMed Central

Soodyall, H.; Vigilant, L.; Hill, A. V.; Stoneking, M.; Jenkins, T.

1996-01-01

The intergenic COII/tRNA(Lys) 9-bp deletion in human mtDNA, which is found at varying frequencies in Asia, Southeast Asia, Polynesia, and the New World, was also found in 81 of 919 sub-Saharan Africans. Using mtDNA control-region sequence data from a subset of 41 individuals with the deletion, we identified 22 unique mtDNA types associated with the deletion in Africa. A comparison of the unique mtDNA types from sub-Saharan Africans and Asians with the 9-bp deletion revealed that sub-Saharan Africans and Asians have sequence profiles that differ in the locations and frequencies of variant sites. Both phylogenetic and mismatch-distribution analysis suggest that 9-bp deletion arose independently in sub-Saharan Africa and Asia and that the deletion has arisen more than once in Africa. Within Africa, the deletion was not found among Khoisan peoples and was rare to absent in western and southwestern African populations, but it did occur in Pygmy and Negroid populations from central Africa and in Malawi and southern African Bantu-speakers. The distribution of the 9-bp deletion in Africa suggests that the deletion could have arisen in central Africa and was then introduced to southern Africa via the recent "Bantu expansion." PMID:8644719

Constructing a philosophy of chiropractic: evolving worldviews and premodern roots☆

PubMed Central

Senzon, Simon A.

2011-01-01

Objective The philosophy of chiropractic can be framed as an attempt to correct the problems inherited from the Western Enlightenment. Its origins can be found in the long tradition of Western philosophy. The purpose of this article is to describe in a broad context chiropractic’s roots in premodernity and establish the structural and hermeneutical differences between chiropractic’s original philosophical ideas and those of premodern philosophers. Discussion The worldview or cultural mindset the philosophy arose from must be situated in the context of its time, the birth of the unique postmodern worldview, aperspectival consciousness, and the modern sense of self. This is accomplished by exploring several metatheories about the development of the self through history, with an emphasis on the premodern roots to the chiropractic terms; Universal Intelligence and Innate Intelligence. By contextualizing the philosophy of chiropractic in terms of a structural genealogy of the self and of ideas, a new approach to philosophy in chiropractic emerges. Conclusion Without accounting for chiropractic’s origins as a reflection of the unique time, place, and culture, in terms of the evolution of worldviews through history, any approach to construct or reconstruct a philosophy of chiropractic will potentially miss the seminal feature of chiropractic’s emergence. PMID:22693478

More than just dancing: experiences of people with Parkinson's disease in a therapeutic dance program.

PubMed

Bognar, Stephanie; DeFaria, Anne Marie; O'Dwyer, Casey; Pankiw, Elana; Simic Bogler, Jennifer; Teixeira, Suzanne; Nyhof-Young, Joyce; Evans, Cathy

2017-06-01

To understand why individuals with Parkinson's disease (PD) participate in a community-based therapeutic dance program and to explore its influence on perceived physical, social and emotional well-being of participants. A qualitative descriptive design was employed using one-on-one semi-structured interviews. Individuals with PD who participated in the Dancing with Parkinson's program were recruited from two locations. Interviews were audio-recorded, transcribed, de-identified and then placed into NVivo 10 software for analysis. A content analysis approach was used with an inductive analysis method to generate a coding scheme. Group discussion facilitated development of overarching themes. Ten participants' responses revealed that the dance program allows for self-improvement and regaining identity through disease self-management. Positive influences of socialization arose through the class, decreasing isolation and improving quality of life. Participants communicate through music and dance to enhance connection with others. Dancing with Parkinson's classes allow for re-development of the social self, which can increase sense of enjoyment in life. Dance programs provide opportunities for social interaction, non-verbal communication and self-improvement, reestablishing self-identity and a sense of usefulness. This study provides unique insight into the experience of participating in a dance program from the perspective of individuals with PD. Implications for rehabilitation Dance is emerging as a strategy to address the physical and psychosocial effects of Parkinson's disease (PD), but little is known regarding participants' perceptions of community-based therapeutic dance programs for PD. This study found that Dancing with Parkinson's (DWP) facilitated an improvement in social participation, resulting in decreased isolation and improved quality of life. Participation in the DWP program can facilitate a positive change in perspective and attitude toward a PD diagnosis, thereby increasing feelings of self-efficacy and improving self-management of the disease. Participants of this study emphasized the multifaceted benefits of DWP, suggesting that it has great potential for addressing not only the physical challenges, but also the cognitive and emotional challenges associated with PD.

[Multiple conjunctival malignant melanomas (author's transl)].

PubMed

Haddad, R

1979-04-01

5 1/2 years after excision of pigmented malignant melanoma which apparently arose in a nevus of the paralimbal bulbar conjunctiva, this 42-year-old male presented himself with a nonpigmented mass of the lid margin which also proved to be a malignant melanoma. "Acquired melanosis sine pigmento" was considered as a site of origin, but histopathologically there is more evidence that this melanoma arose in a non-pigmented compound nevus.

Understanding and preventing type 1 diabetes through the unique working model of TrialNet.

PubMed

Battaglia, Manuela; Anderson, Mark S; Buckner, Jane H; Geyer, Susan M; Gottlieb, Peter A; Kay, Thomas W H; Lernmark, Åke; Muller, Sarah; Pugliese, Alberto; Roep, Bart O; Greenbaum, Carla J; Peakman, Mark

2017-11-01

Type 1 diabetes is an autoimmune disease arising from the destruction of pancreatic insulin-producing beta cells. The disease represents a continuum, progressing sequentially at variable rates through identifiable stages prior to the onset of symptoms, through diagnosis and into the critical periods that follow, culminating in a variable depth of beta cell depletion. The ability to identify the very earliest of these presymptomatic stages has provided a setting in which prevention strategies can be trialled, as well as furnishing an unprecedented opportunity to study disease evolution, including intrinsic and extrinsic initiators and drivers. This niche opportunity is occupied by Type 1 Diabetes TrialNet, an international consortium of clinical trial centres that leads the field in intervention and prevention studies, accompanied by deep longitudinal bio-sampling. In this review, we focus on discoveries arising from this unique bioresource, comprising more than 70,000 samples, and outline the processes and science that have led to new biomarkers and mechanistic insights, as well as identifying new challenges and opportunities. We conclude that via integration of clinical trials and mechanistic studies, drawing in clinicians and scientists and developing partnership with industry, TrialNet embodies an enviable and unique working model for understanding a disease that to date has no cure and for designing new therapeutic approaches.

Understanding and preventing type 1 diabetes through the unique working model of TrialNet

PubMed Central

Anderson, Mark S.; Buckner, Jane H.; Geyer, Susan M.; Gottlieb, Peter A.; Kay, Thomas W. H.; Lernmark, Åke; Muller, Sarah; Pugliese, Alberto; Roep, Bart O.; Greenbaum, Carla J.

2018-01-01

Type 1 diabetes is an autoimmune disease arising from the destruction of pancreatic insulin-producing beta cells. The disease represents a continuum, progressing sequentially at variable rates through identifiable stages prior to the onset of symptoms, through diagnosis and into the critical periods that follow, culminating in a variable depth of beta cell depletion. The ability to identify the very earliest of these presymptomatic stages has provided a setting in which prevention strategies can be trialled, as well as furnishing an unprecedented opportunity to study disease evolution, including intrinsic and extrinsic initiators and drivers. This niche opportunity is occupied by Type 1 Diabetes TrialNet, an international consortium of clinical trial centres that leads the field in intervention and prevention studies, accompanied by deep longitudinal bio-sampling. In this review, we focus on discoveries arising from this unique bioresource, comprising more than 70,000 samples, and outline the processes and science that have led to new biomarkers and mechanistic insights, as well as identifying new challenges and opportunities. We conclude that via integration of clinical trials and mechanistic studies, drawing in clinicians and scientists and developing partnership with industry, TrialNet embodies an enviable and unique working model for understanding a disease that to date has no cure and for designing new therapeutic approaches. PMID:28770323

Opportunities of using bio-based materials for value-added composites

Treesearch

Zhiyong Cai

2010-01-01

Our forests are a naturally renewable resource that has been used as a principal source of bio-energy and building materials for centuries. The growth of world population and affluence has resulted in substantial increases in demand and in consumption for all raw materials. Resulting increases in demand for wood products provides a unique opportunity for developing new...

Putting Making into High School Computer Science Classrooms: Promoting Equity in Teaching and Learning with Electronic Textiles in "Exploring Computer Science"

ERIC Educational Resources Information Center

Fields, Deborah Ann; Kafai, Yasmin; Nakajima, Tomoko; Goode, Joanna; Margolis, Jane

2018-01-01

Recent discussions of making have focused on developing out-of-school makerspaces and activities to provide more equitable and enriching learning opportunities for youth. Yet school classrooms present a unique opportunity to help broaden access, diversify representation, and deepen participation in making. In turning to classrooms, we want to…

HPV vaccine catch up schedule - an opportunity for chlamydia screening.

PubMed

Grotowski, Miriam; May, Jenny

2008-07-01

The human papillomavirus (HPV) vaccine (Gardasil) catch up schedule in general practice is available until June 2009 to females not in school and under the age of 27 years. A course of three injections is given over 6 months. This provides a unique opportunity for sexual health screening in an age group where chlamydia screening is a priority.

Providing Written Feedback on Students' Mathematical Arguments: Proof Validations of Prospective Secondary Mathematics Teachers

ERIC Educational Resources Information Center

Bleiler, Sarah K.; Thompson, Denisse R.; Krajcevski, Milé

2014-01-01

Mathematics teachers play a unique role as experts who provide opportunities for students to engage in the practices of the mathematics community. Proof is a tool essential to the practice of mathematics, and therefore, if teachers are to provide adequate opportunities for students to engage with this tool, they must be able to validate student…

Cascabel prescribed fire long-term watershed study: an opportunity to monitor climate change

Treesearch

Gerald Gottfried; Daniel Neary; Peter Ffolliott; Karen Koestner

2012-01-01

Experimental watershed studies can provide answers to new challenges facing land managers and society including the impacts of fires and climate change on upstream and regional hydrology. The Cascabel Watersheds long-term prescribed fire study provides a unique opportunity to monitor climate change because of its location in an oak savanna situated between deserts or...

Universal Design and LGBTQ (Lesbian, Gay, Transgender, Bisexual, and Queer) Issues: Creating Equal Access and Opportunities for Success

ERIC Educational Resources Information Center

Daniels, Jennifer R.; Geiger, Tracy J.

2010-01-01

The authors extend the ideals set forth by the universal design (UD) framework seeking to include the unique needs of students in the lesbian, gay, bisexual, transgender, and queer (LGBTQ) community. Universal design is a philosophy that, when applied to higher education, constitutes acceptance of, equal access for, and equal opportunities for…

Law in Translation: Challenges and Opportunities in Teaching International Students in Business Law and Legal Environment Courses

ERIC Educational Resources Information Center

Dove, Laura R.; Bryant, Natalie P.

2016-01-01

The purpose of this article is to outline the unique challenges faced by international students enrolled in business law or legal environment of business courses. It is also imperative to recognize the numerous opportunities that instructors can create in business law classrooms that will enhance the experience of all students given the…

Tradition and Culture in the Millennium: Tribal Colleges and Universities. Educational Policy in the 21st Century: Opportunities, Challenges and Solutions

ERIC Educational Resources Information Center

Warner, Linda Sue, Ed.; Gipp, Gerald E., Ed.

2009-01-01

This volume of The David C. Anchin Research Center Series on Educational Policy in the 21st century: Opportunities, Challenges, and Solutions focuses on tribal colleges and universities. As a recent member of higher education community, tribal colleges and universities provide a unique perspective on higher education policy. Policies and…

Consanguinity in Saudi Arabia: a unique opportunity for pediatric kidney research.

PubMed

Kari, Jameela A; Bockenhauer, Detlef; Stanescu, Horia; Gari, Mamdooh; Kleta, Robert; Singh, Ajay K

2014-02-01

Identification of disease-related genes is a critical step in understanding the molecular basis of disease and developing targeted therapies. The genetic study of diseases occurring in the offspring of consanguineous unions is a powerful way to discover new disease genes. Pediatric nephrology provides an excellent example because ∼70% of cases of kidney disease in childhood are congenital with a likely genetic basis. This percentage is likely to be even higher in countries with a high consanguinity rate, such as the Kingdom of Saudi Arabia. However, there are a number of challenges, such as cultural, legal, and religious restrictions, that should be appreciated before carrying out genetic research in a tradition-bound country. In this article, we discuss the background, opportunities, and challenges involved with this unique opportunity to conduct studies of such genetic disorders. Keys to success include collaboration and an understanding of local traditions and laws. Copyright © 2014 National Kidney Foundation, Inc. All rights reserved.

A Case Study in Classroom Management and School Involvement: Designing an Art Room for Effective Learning

ERIC Educational Resources Information Center

Broome, Jeffrey L.

2013-01-01

The purpose of this research project is to investigate the design of classroom environments through the lens of a uniquely selected art educator. More specifically, the purpose is to use case study methodology (Stake, 1995) to characterize the resulting instructional experiences for an art educator who had the unique opportunity to collaborate…

YogaHome: teaching and research challenges in a yoga program with homeless adults.

PubMed

Davis-Berman, Jennifer; Farkas, Jean

2012-01-01

YogaHome is a therapeutic yoga program for homeless women. Developing and refining YogaHome provided a unique opportunity to explore the process of teaching yoga to women faced with the physical and emotional stress of living in a homeless shelter. Unique teaching and research challenges are presented and recommendations for future programs are discussed.

The challenge of doing science in wilderness: historical, legal, and policy context

Treesearch

Peter Landres; Judy Alderson; David J. Parsons

2003-01-01

Lands designated by Congress under the Wilderness Act of 1964 (Public Law 88-577) offer unique opportunities for social and biophysical research in areas that are relatively unmodified by modern human actions. Wilderness designation also imposes a unique set of constraints on the methods that may be used or permitted to conduct this research. For example, legislated...

Growing Strategic Thinkers for the Air National Guard

DTIC Science & Technology

2010-06-03

their career field and the strategic theory and critical thinking developed through advanced educational opportunities. The uniqueness of the ... theory - while others advocate leaders can be developed through experiences and education. This chapter will argue that to have the most effective... the military genius encapsulates unique traits that allow him to see and process information much more quickly and accurately than the ordinary

Understanding Our Service-Learning Community: An Exploratory Study of Parent, Teacher, and Student Perceptions about Childhood Obesity

ERIC Educational Resources Information Center

Massey-Sokes, Marilyn; Meaney, Karen S.

2006-01-01

Childhood obesity has reached epidemic proportions in the U.S. University health and physical education programs have a unique opportunity to assist in childhood obesity prevention through service-learning programs. However, prior to the implementation of service-learning curricula, it is imperative to gain insight in the unique needs of the…

Book clubs--outreach opportunities for hospital libraries.

PubMed

Stephenson, Priscilla L; Clever, Shannon; Coady, Teresa R; Ender, Deniz; Heyd, Michael; Peth, Sara

2014-01-01

Book clubs and discussion groups provide opportunities for hospital librarians to reach out to staff from all areas of their facilities while introducing them to literature reflecting participants' personal and professional interests. Librarians presenting these case studies have coordinated local book clubs where topics ranged from titles about the nature of healing, to leadership development, and patient-centered care. Some also included contemporary novels of interest to participants. No matter the setting or scope of material discussed, each group has provided unique networking opportunities for staff to meet others working in various departments of their facilities.

Pain

MedlinePlus

... NCCIH Researchers Describe Specialized Neurons That Play a Unique Role in Mechanical Pain ( August 16, 2017 ) ... Funding for Pain Initiatives Current Funding Opportunities Research on the Impact of Creative Arts in Military ...

Sand Dunes of Nili Patera in 3-D

NASA Technical Reports Server (NTRS)

2001-01-01

The most exciting new aspect of the Mars Global Surveyor (MGS) Extended Mission is the opportunity to turn the spacecraft and point the Mars Orbiter Camera (MOC) at specific features of interest. Opportunities to point the spacecraft come about ten times a week. Throughout the Primary Mission (March 1999 - January 2001), nearly all MGS operations were conducted with the spacecraft pointing 'nadir'--that is, straight down. A search for the missing Mars Polar Lander in late 1999 and early 2000 demonstrated that pointing the spacecraft could allow opportunities for MOC to see things that simply had not entered its field of view during typical nadir-looking operations, and to target areas previously seen in a nadir view so that stereo ('3-D') pictures could be derived.

One of the very first places photographed by the MOC at the start of the Mapping Mission in March 1999 was a field of dunes located in Nili Patera, a volcanic depression in central Syrtis Major. A portion of this dune field was shown in a media release on March 11, 1999, 'Sand Dunes of Nili Patera, Syrtis Major'. Subsequently, the image was archived with the NASA Planetary Data System, as shown in the Malin Space Science Systems MOC Gallery. On April 24, 2001, an opportunity arose in which the MGS could be pointed off-nadir to take a new picture of the same dune field. By combining the nadir view from March 1999 and the off-nadir view from April 2001, a stereoscopic image was created. The anaglyph shown here must be viewed with red (left-eye) and blue (right-eye) '3-D' glasses. The dunes and the local topography of the volcanic crater's floor stand out in sharp relief. The images, taken more than one Mars year apart, show no change in the shape or location of the dunes--that is, they do not seem to have moved at all since March 1999.

The Plurality of Harbors at Caesarea: The Southern Anchorage in Late Antiquity

NASA Astrophysics Data System (ADS)

Ratzlaff, Alexandra; Galili, Ehud; Waiman-Barak, Paula; Yasur-Landau, Assaf

2017-08-01

The engineering marvel of Sebastos, or Portus Augusti as it was called in Late Antiquity (284-638 CE), dominated Caesarea's harbor center along modern Israel's central coast but it was only one part of a larger maritime complex. The Southern Anchorage provides a case study as one portion of the Caesarea complex, as well as a node within the regional network of anchorages and small harbors. Ceramics recovered from here show a high percentage of locally, and provincially, produced storage jars engaged in maritime trade. The ceramic evidence points towards an intensified regional trade or cabotage rather than favouring long distance trade from large port to port. Working out of these small harbors, opportunities arose for greater flexibility in specialization of commodities and materials passing through the network of subsidiary ports, contributing to a more diversified market economy. This analysis provides another example in the growing focus on how these simple and semi-modified anchorages in the Eastern Mediterranean were often the predominant economic networks connecting hinterland and coastal trade.

Chandra X-Ray Observatory Observations of the Jovian System

NASA Technical Reports Server (NTRS)

Elsner, R. F.; Bhardwaj, A.; Gladstone, R.; Waite, J. H.; Ford, P.; Branduari-Raymont, G.

2005-01-01

Chandra X-ray Observatory (CXO) and XMM-Newton observations of x-rays from the Jovian system have answered questions that arose from early observations with the Einstein and Rosat X-ray Observatories, but in the process of vastly increasing our knowledge of x-ray emission from Jupiter and its environs they have also raised new questions and point to new opportunities for future studies. We will review recent x-ray results on the Jovian system, from the point of view of the CXO, and discuss various questions that have arisen in the course of our studies. We will discuss prospects for more observations in the immediate future, and how they might address open questions. Finally we will briefly describe ways in which an imaging x-ray spectrometer in the vicinity of the Jovian system could provide a wealth of data and results concerning Jupiter's x-ray auroral and disk emission, elemental abundance measurements for the Galilean moons, and detailed studies of x-ray emission from the Io Plasma Torus.

LESSONS LEARNED AND NEXT STEPS FOR BUILDING KNOWLEDGE ABOUT TRIBAL MATERNAL, INFANT, AND EARLY CHILDHOOD HOME VISITING.

PubMed

Whitmore, Corrie B; Sarche, Michelle; Ferron, Cathy; Moritsugu, John; Sanchez, Jenae G

2018-05-16

Authors in this Special Issue of the Infant Mental Health Journal shared the work of the first three cohorts of Tribal Maternal, Infant, and Early Childhood Home Visiting (MIECHV) grantees funded by the Administration for Children and Families. Since 2010, Tribal MIECHV grantees have served families and children prenatally to kindergarten entry in American Indian and Alaska Native (AI/AN) communities across the lower 48 United States and Alaska. Articles highlighted challenges and opportunities that arose as grantees adapted, enhanced, implemented, and evaluated their home-visiting models. This article summarizes nine lessons learned across the articles in this Special Issue. Lessons learned address the importance of strengths-based approaches, relationship-building, tribal community stakeholder involvement, capacity-building, alignment of resources and expectations, tribal values, adaptation to increase cultural and contextual attunement, indigenous ways of knowing, community voice, and sustainability. Next steps in Tribal MIECHV are discussed in light of these lessons learned. © 2018 Michigan Association for Infant Mental Health.

A practice-based evaluation of a liquid barrier film.

PubMed

Harding, Nicola

2002-05-01

In palliative care it is often the little things such as being comfortable that help to improve a patient's quality of life. When the opportunity arose in our hospice to take part in a practice-based evaluation of a product that promised to make patients more comfortable, we were pleased to take part. Our small-scale evaluation was part of a wider study of SuperSkin, a liquid barrier film designed to protect skin at risk of damage. Information was collected from the patient, patient's medical notes and the nursing staff - a patient daily diary record was used in addition to normal information recordings. We evaluated the efficacy of the product and found this liquid barrier film to have a positive effect in several ways. It appeared to assist in the healing of skin damaged by friction and shearing forces, and from excoriation from wound exudates, urine and faeces. In addition, it appeared to protect healthy, 'at risk' skin from the same problems.

A democratic and student-centred approach to facilitating teamwork learning among first-year engineering students: a learning and teaching case study

NASA Astrophysics Data System (ADS)

Missingham, Dorothy; Matthews, Robert

2014-07-01

This work examines an innovative and evolving approach to facilitating teamwork learning in a generic first-year mechanical engineering course. Principles of inclusive, student-active and democratic pedagogy were utilised to engage students on both the social and personal planes. Learner opportunities to facilitate, direct and lead the learning direction were emphasised. This emphasis encouraged a rich learning process and motivated students dismissive of the need to examine their communication skills and those who initially perceived the topic as a personal intrusion. Through a sharing of curriculum decisions, a climate of trust, ownership and shared value arose. Students chose from a range of tools across personality-type indicators, learning style indicators and hierarchies of human needs, to assist their capacity to express and discuss engineering designs and concepts. Peer teaching and collaborative exercises were incorporated to provide an authentic learning context and to further the student's sense of ownership.

Mapping the war: gender, health, and the medical profession in France and Germany, 1914-1918.

PubMed

Michl, Susanne

2014-01-01

This article compares the gender and health politics of the German and the French medical professions, which incorporated military command structures into their civilian self-conception. Mobilized doctors committed themselves to the new circumstances and opportunities offered by the war. They applied the established military spatial 'map' which distinguished between the male-dominated front and the female-dominated home front and turned it into an epidemiological map, identifying danger zones which arose from points of contact between men and women. The analysis singles out two case studies: the rapid spread of venereal disease and psychiatric disorders. These case studies allow for a comparative analysis of the following questions: How did doctors assess the impacts of the war on the individual and the society as a whole? How did they view the war's impact on conventional gender orders, individual and national health? And how did they see their own role as a part of an independent civilian profession?

The science case for simultaneous mm-wavelength receivers in radio astronomy

NASA Astrophysics Data System (ADS)

Dodson, Richard; Rioja, María J.; Jung, Taehyun; Goméz, José L.; Bujarrabal, Valentin; Moscadelli, Luca; Miller-Jones, James C. A.; Tetarenko, Alexandra J.; Sivakoff, Gregory R.

2017-11-01

This review arose from the European Radio Astronomy Technical Forum (ERATec) meeting held in Firenze, October 2015, and aims to highlight the breadth and depth of the high-impact science that will be aided and assisted by the use of simultaneous mm-wavelength receivers. Recent results and opportunities are presented and discussed from the fields of: continuum VLBI (observations of weak sources, astrometry, observations of AGN cores in spectral index and Faraday rotation), spectral line VLBI (observations of evolved stars and massive star-forming regions) and time domain observations of the flux variations arising in the compact jets of X-ray binaries. Our survey brings together a large range of important science applications, which will greatly benefit from simultaneous observing at mm-wavelengths. Such facilities are essential to allow these applications to become more efficient, more sensitive and more scientifically robust. In some cases without simultaneous receivers the science goals are simply unachievable. Similar benefits would exist in many other high frequency astronomical fields of research.

Chromosome stickiness impairs meiosis and influences reproductive success in Panicum maximum (Poaceae) hybrid plants.

PubMed

Pessim, C; Pagliarini, M S; Silva, N; Jank, L

2015-04-28

Chromosome stickiness has been studied in several species of higher plants and is characterized by sticky clumps of chromatin resulting in sterility. Chromosome stickiness was recorded in Panicum maximum hybrid plants that were cultivated in the field. In the meiocytes affected, chromosomes clumped into amorphous masses that did not orient themselves on the equatorial plate, and anaphase I disjunction failed to occur. After a normal cytokinesis, the masses of chromatin were divided between both daughter cells. Metaphase and anaphase of the second division also did not occur, and after the second cytokinesis, polyads were formed. This abnormality arose spontaneously. Abnormalities that cause male sterility are an important tool for obtaining hybrid seeds in plant breeding. This is the first report of an abnormality affecting pollen viability in P. maximum. This finding can open a new opportunity in the breeding program of this species that is devoted to hybridization where manual cross-pollination is difficult and time consuming.

Digital Dividend Aware Business Models for the Creative Industries: Challenges and Opportunities in EU Markets

NASA Astrophysics Data System (ADS)

Cossiavelou, Vassiliki

EU counties have a historically unique opportunity to enable their creative industries to promote the knowledge societies, applying new business models to their media content and networks markets, that are digital dividend (DD) aware. This new extra-media gatekeeping factor could shape new alliances and co operations among the member states and the global media markets, as well.

European School of Internal Medicine: a window of opportunity for RCP activities in Europe.

PubMed

Davidson, Chris; Higgens, Clare

2009-04-01

The Royal College of Physicians (RCP) is to host the European School of Internal Medicine for two years from 2009-10. This affords a unique opportunity for specialist registrars to exchange ideas about professional development and training and to make contacts with young internists from across Europe. Such links should prove useful for future RCP initiatives in European medicine.

The Effects of Autonomy-Supportive vs. Controlling Guidance on Learners' Motivational and Cognitive Achievement in a Structured Field Trip

ERIC Educational Resources Information Center

Basten, Melanie; Meyer-Ahrens, Inga; Fries, Stefan; Wilde, Matthias

2014-01-01

Field trips can provide unique opportunities for authentic, meaningful, and self-determined learning. Capitalizing on these opportunities requires that field trips be structured. A common way to do this is through the use of educational materials such as worksheets. The extent to which the guide's or teacher's autonomy-supportive or…

Propagation measurements in Alaska using ACTS beacons

NASA Technical Reports Server (NTRS)

Mayer, Charles E.

1991-01-01

The placement of an ACTS propagation terminal in Alaska has several distinct advantages. First is the inclusion of a new and important climatic zone to the global propagation model. Second is the low elevation look angle from Alaska to ACTS. These two unique opportunities also present problems unique to the location, such as extreme temperatures and lower power levels. These problems are examined and compensatory solutions are presented.

Mars exploration program analysis group goal one: determine if life ever arose on Mars.

PubMed

Hoehler, Tori M; Westall, Frances

2010-11-01

The Mars Exploration Program Analysis Group (MEPAG) maintains a standing document that articulates scientific community goals, objectives, and priorities for mission-enabled Mars science. Each of the goals articulated within the document is periodically revisited and updated. The astrobiology-related Goal One, "Determine if life ever arose on Mars," has recently undergone such revision. The finalized revision, which appears in the version of the MEPAG Goals Document posted on September 24, 2010, is presented here.

ORCID Uptake in the Astronomical Community

NASA Astrophysics Data System (ADS)

Holmquist, Jane

2015-08-01

The IAU General Assembly provides librarians with a unique opportunity to interact with astronomers from all over the world. From the perspective of an ORCID Ambassador, the Focus Group Meeting on "Scholarly Publication in Astronomy" also provides an opportunity to demonstrate the cooperation and collaboration needed by individual astronomers, societies, librarians, publishers and bibliographic database providers to achieve universal adoption of ORCID, a standard unique identifier for authors, just as the DOI (digital object identifier) has been adopted for each journal article published.I propose to 1) present at the Focus Group Meeting an update on the uptake of ORCID by members of the astronomical community and 2) set up a small station (TBA) near the IAU registration area where librarians can show researchers how to register for an ORCID in 30 seconds.

New commercial opportunities for advanced reproductive technologies in horses, wildlife, and companion animals.

PubMed

Long, C R; Walker, S C; Tang, R T; Westhusin, M E

2003-01-01

As advanced reproductive technologies become more efficient and repeatable in livestock and laboratory species, new opportunities will evolve to apply these techniques to alternative and non-traditional species. This will result in new markets requiring unique business models that address issues of animal welfare and consumer acceptance on a much different level than the livestock sector. Advanced reproductive technologies and genetic engineering will be applied to each species in innovative ways to provide breeders more alternatives for the preservation and propagation of elite animals in each sector. The commercialization of advanced reproductive techniques in these niche markets should be considered a useful tool for conservation of genetic material from endangered or unique animals as well as production of biomedical models of human disease. Copyright 2002 Elsevier Science Inc.

Employment Opportunities for Family Members in Germany.

DTIC Science & Technology

1983-05-24

30 V . NEW INITIATIVES TO IMPROVE FAMILY MEMBER EMPLOYMENT OPPORTUNITIES ........ ...................... . 40 VI. OBSERVATIONS AND COMMENTS...I, II, V Local National Hire 9.94% 2.5% 6.52% 1.93% 12.07% NOTES 1. CONUS Hire Fringe Benefits include overseas unique estimated costs outlined in...from a survey of ODCSRM FY81 vouchers . 19 TABLE 3-4 FY83 GENERAL SCHEDULE CONUS HIRE CIVILIAN COST FACTORS This table provides cost factors for

Opportunities for Science on the ISS: A Unique Laboratory Environment

NASA Technical Reports Server (NTRS)

Kugler, Justin; Edeen, Marybeth

2010-01-01

This slide presentation reviews the opportunities for scientific discoveries on the International Space Station (ISS). With the crew tended, and availability of long-term studies and the capabilities of the ISS (i.e. microgravity, exposure to the thermosphere and observations at high altitude and velocity) there are many examples of scientific experiments. There are several examples showing that microgravity is different from the effects of gravity.

Aging in the United States: Opportunities and Challenges for Otolaryngology-Head and Neck Surgery.

PubMed

Chiu, Brandon L; Pinto, Jayant M

2018-05-17

The number of Americans over the age of 65 has been growing much faster than the overall population's growth rate. These changes can be largely attributed to the improvement in life expectancy. This demographic shift yields a unique and exciting opportunity to provide both expedient and cost-efficient care to a growing patient population. Copyright © 2018 Elsevier Inc. All rights reserved.

The Use of Video Self-Monitoring Embedded with Mentorship as a Medium to Enhance Experiential Learning Opportunities and Promote Critical Thinking Skills for Educators and Health Science Professionals Working with Children with Autism

ERIC Educational Resources Information Center

Slim-Topdjian, Lina; Pinto Zipp, Genevieve

2016-01-01

The increased prevalence of autism has created an increased challenge for teachers to incorporate specialized teaching strategies to address the unique educational and behavioral challenges facing children diagnosed with autism. Providing teachers with educational training opportunities will promote such learning. In the academic world,…

Investigating Affordance of Opportunity for Young Children's Language Interactions in a Nursery Setting: How Can Small Group Talk Act as a Forum for Language Learning?

ERIC Educational Resources Information Center

King, Sarah Elizabeth; Dockrell, Julie E.

2016-01-01

The importance of research on the unique nature of the communication supporting environment in nurseries has been heightened by growing evidence of the significance of early language skills for later academic and social development. This study focussed on children's language use during small group times. Opportunities to hear and practise language…

A guide to transportation enhancements

DOT National Transportation Integrated Search

2004-12-01

The Federal Transportation Enhancement Program offers extensive opportunities to take unique and creative actions to integrate transportation into our communities and the natural environment. Transportation enhancement activities can be stand-alone p...

Sauvages' paperwork: how disease classification arose from scholarly note-taking.

PubMed

Hess, Volker; Mendelsohn, Andrew

2014-01-01

What was classification as it first took modern form in the eighteenth century, and how did it relate to earlier ways of describing and ordering? We offer new answers to these questions by examining medicine rather than botany and by reconstructing practice on paper. First among disease classifications was the 'nosology' of the Montpellier physician François Boissier de Sauvages de Lacroix. Analysis of his hitherto unstudied notebooks and of the nosology's many editions (1731-1772) shows that Boissier de Sauvages broke with earlier physicians' humanistic ordering of disease while sustaining the paper practices they had used. Scientific method was scholarly method. Classification arose through an incomplete break with, and intensified practice of, a past library-based way of ordering the described world. A new empiricism of generalizations (species) arose out of an older one of particulars (observationes). This happened through the rewriting--not the replacement--of the canon of disease knowledge since antiquity and its reordering on the printed page.

Human evolution. Evolution of early Homo: an integrated biological perspective.

PubMed

Antón, Susan C; Potts, Richard; Aiello, Leslie C

2014-07-04

Integration of evidence over the past decade has revised understandings about the major adaptations underlying the origin and early evolution of the genus Homo. Many features associated with Homo sapiens, including our large linear bodies, elongated hind limbs, large energy-expensive brains, reduced sexual dimorphism, increased carnivory, and unique life history traits, were once thought to have evolved near the origin of the genus in response to heightened aridity and open habitats in Africa. However, recent analyses of fossil, archaeological, and environmental data indicate that such traits did not arise as a single package. Instead, some arose substantially earlier and some later than previously thought. From ~2.5 to 1.5 million years ago, three lineages of early Homo evolved in a context of habitat instability and fragmentation on seasonal, intergenerational, and evolutionary time scales. These contexts gave a selective advantage to traits, such as dietary flexibility and larger body size, that facilitated survival in shifting environments. Copyright © 2014, American Association for the Advancement of Science.

Modeling recent human evolution in mice by expression of a selected EDAR variant

PubMed Central

Kamberov, Yana G.; Wang, Sijia; Tan, Jingze; Gerbault, Pascale; Wark, Abigail; Tan, Longzhi; Yang, Yajun; Li, Shilin; Tang, Kun; Chen, Hua; Powell, Adam; Itan, Yuval; Fuller, Dorian; Lohmueller, Jason; Mao, Junhao; Schachar, Asa; Paymer, Madeline; Hostetter, Elizabeth; Byrne, Elizabeth; Burnett, Melissa; McMahon, Andrew P.; Thomas, Mark G.; Lieberman, Daniel E.; Jin, Li; Tabin, Clifford J.; Morgan, Bruce A.; Sabeti, Pardis C.

2013-01-01

Summary An adaptive variant of the human Ectodysplasin receptor, EDARV370A, is one of the strongest candidates of recent positive selection from genome-wide scans. We have modeled EDAR370A in mice and characterized its phenotype and evolutionary origins in humans. Our computational analysis suggests the allele arose in Central China approximately 30,000 years ago. Although EDAR370A has been associated with increased scalp hair thickness and changed tooth morphology in humans, its direct biological significance and potential adaptive role remain unclear. We generated a knock-in mouse model and find that, as in humans, hair thickness is increased in EDAR370A mice. We identify novel biological targets affected by the mutation, including mammary and eccrine glands. Building on these results, we find that EDAR370A is associated with an increased number of active eccrine glands in the Han Chinese. This interdisciplinary approach yields unique insight into the generation of adaptive variation among modern humans. PMID:23415220

Hippocampal Theta-Gamma Coupling Reflects State-Dependent Information Processing in Decision Making.

PubMed

Amemiya, Seiichiro; Redish, A David

2018-03-20

During decision making, hippocampal activity encodes information sometimes about present and sometimes about potential future plans. The mechanisms underlying this transition remain unknown. Building on the evidence that gamma oscillations at different frequencies (low gamma [LG], 30-55 Hz; high gamma [HG], 60-90 Hz; and epsilon, 100-140 Hz) reflect inputs from different circuits, we identified how changes in those frequencies reflect different information-processing states. Using a unique noradrenergic manipulation by clonidine, which shifted both neural representations and gamma states, we found that future representations depended on gamma components. These changes were identifiable on each cycle of theta as asymmetries in the theta cycle, which arose from changes within the ratio of LG and HG power and the underlying phases of those gamma rhythms within the theta cycle. These changes in asymmetry of the theta cycle reflected changes in representations of present and future on each theta cycle. Copyright © 2018 The Author(s). Published by Elsevier Inc. All rights reserved.

Unmarked: An R package for fitting hierarchical models of wildlife occurrence and abundance

USGS Publications Warehouse

Fiske, I.J.; Chandler, R.B.

2011-01-01

Ecological research uses data collection techniques that are prone to substantial and unique types of measurement error to address scientic questions about species abundance and distribution. These data collection schemes include a number of survey methods in which unmarked individuals are counted, or determined to be present, at spatially- referenced sites. Examples include site occupancy sampling, repeated counts, distance sampling, removal sampling, and double observer sampling. To appropriately analyze these data, hierarchical models have been developed to separately model explanatory variables of both a latent abundance or occurrence process and a conditional detection process. Because these models have a straightforward interpretation paralleling mecha- nisms under which the data arose, they have recently gained immense popularity. The common hierarchical structure of these models is well-suited for a unied modeling in- terface. The R package unmarked provides such a unied modeling framework, including tools for data exploration, model tting, model criticism, post-hoc analysis, and model comparison.

Gene duplication and phylogeography of North American members of the Hart Park serogroup of avian rhabdoviruses.

PubMed

Allison, Andrew B; Mead, Daniel G; Palacios, Gustavo F; Tesh, Robert B; Holmes, Edward C

2014-01-05

Flanders virus (FLAV) and Hart Park virus (HPV) are rhabdoviruses that circulate in mosquito-bird cycles in the eastern and western United States, respectively, and constitute the only two North American representatives of the Hart Park serogroup. Previously, it was suggested that FLAV is unique among the rhabdoviruses in that it contains two pseudogenes located between the P and M genes, while the cognate sequence for HPV has been lacking. Herein, we demonstrate that FLAV and HPV do not contain pseudogenes in this region, but encode three small functional proteins designated as U1-U3 that apparently arose by gene duplication. To further investigate the U1-U3 region, we conducted the first large-scale evolutionary analysis of a member of the Hart Park serogroup by analyzing over 100 spatially and temporally distinct FLAV isolates. Our phylogeographic analysis demonstrates that although FLAV appears to be slowly evolving, phylogenetically divergent lineages co-circulate sympatrically. © 2013 Published by Elsevier Inc.

'Cost in transliteration': the neurocognitive processing of Romanized writing.

PubMed

Rao, Chaitra; Mathur, Avantika; Singh, Nandini C

2013-03-01

Romanized transliteration is widely used in internet communication and global commerce, yet we know little about its behavioural and neural processing. Here, we show that Romanized text imposes a significant neurocognitive load. Readers faced greater difficulty in identifying concrete words written in Romanized transliteration (Romanagari) compared to L1 and L2. Functional neuroimaging revealed that the neural cost of processing transliterations arose from significantly greater recruitment of language (left precentral gyrus, left inferior parietal lobule) and attention networks (left mid-cingulum). Additionally, transliterated text uniquely activated attention and control areas compared to both L1 (cerebellar vermis) and L2 (pre-supplementary motor area/pre-SMA). We attribute the neural effort of reading Romanized transliteration to (i) effortful phonological retrieval from unfamiliar orthographic forms and (ii) conflicting attentional demands imposed by mapping orthographic forms of one language to phonological-semantic representations in another. Finally, significant brain-behaviour correlation suggests that the left mid-cingulum modulates cognitive-linguistic conflict. Copyright © 2013 Elsevier Inc. All rights reserved.

Sampling bias in an international internet survey of diversion programs in the criminal justice system.

PubMed

Hartford, Kathleen; Carey, Robert; Mendonca, James

2007-03-01

Despite advances in the storage and retrieval of information within health care systems, health researchers conducting surveys for evaluations still face technical barriers that may lead to sampling bias. The authors describe their experience in administering a Web-based, international survey to English-speaking countries. Identifying the sample was a multistage effort involving (a) searching for published e-mail addresses, (b) conducting Web searches for publicly funded agencies, and (c) performing literature searches, personal contacts, and extensive Internet searches for individuals. After pretesting, the survey was converted into an electronic format accessible by multiple Web browsers. Sampling bias arose from (a) system incompatibility, which did not allow potential respondents to open the survey, (b) varying institutional gate-keeping policies that "recognized" the unsolicited survey as spam, (c) culturally unique program terminology, which confused some respondents, and (d) incomplete sampling frames. Solutions are offered to the first three problems, and the authors note that sampling bias remains a crucial problem.

"Our lives aren't over": A strengths-based perspective on stigma, discrimination, and coping among young parents.

PubMed

Conn, Bridgid Mariko; de Figueiredo, Sophie; Sherer, Sara; Mankerian, Meray; Iverson, Ellen

2018-05-23

The current study conducted interviews and focus groups with twenty-four diverse 16-25 year-old parents to elicit in-depth narratives about experiences related to parenting status. Parents were recruited from a case management program in the Southwestern United States supporting high school graduation and workforce employment (for mothers and fathers, respectively). Young parents disclosed experiences of shame, stigma, and discrimination associated with perceptions about their "fitness" to be a parent and moral judgment. Themes arose that revealed the positive, adaptive ways that participants coped with potentially deleterious experiences with a focus on their role as a parent and role model for their children. Our findings highlight positive meaning-making and resiliency of young parents when confronted with discrimination and systemic barriers, with many participants focusing on the benefits of parenthood within a unique developmental context. Further, implications for program development, provider trainings, and public policy and advocacy efforts for young parents are discussed. Copyright © 2018. Published by Elsevier Ltd.

HIV prevention and the two faces of partner notification.

PubMed Central

Bayer, R; Toomey, K E

1992-01-01

In the cases of medical patients with sexually transmitted diseases (particularly those with the human immunodeficiency virus), two distinct approaches exist to notifying sexual and/or needle-sharing partners of possible risk. Each approach has its own history (including unique practical problems of implementation) and provokes its own ethical dilemmas. The first approach--the moral "duty to warn"--arose out of clinical situations in which a physician knew the identity of a person deemed to be at risk. The second approach--that of contact tracing--emerged from sexually transmitted disease control programs in which the clinician typically did not know the identity of those who might have been exposed. Confusion between the two approaches has led many to mistake processes that are fundamentally voluntary as mandatory and those that respect confidentiality as invasive of privacy. In the context of the AIDS epidemic and the vicissitudes of the two approaches, we describe the complex problems of partner notification and underscore the ethical and political contexts within which policy decisions have been made. PMID:1304728

Chinese and South Asian Religious Institutions and HIV Prevention in New York City

PubMed Central

Chin, John J.; Mantell, Joanne; Weiss, Linda; Bhagavan, Mamatha; Luo, Xiaoting

2012-01-01

Religious institutions in Asian immigrant communities are in a unique position to confront the challenges of the HIV epidemic for the populations they serve. However, there has been little research on whether these institutions are willing or able to take a role in HIV prevention. This article reports on findings from a qualitative study of three Asian immigrant religious institutions in New York City (a Buddhist temple, a Hindu temple, an Islamic center/mosque) that are part of a larger study of Asian immigrant community institutions and their response to the HIV epidemic. Several prominent themes arose that formed the basis of a preliminary theoretical framework describing the way Asian immigrant religious institutions may evaluate their role in HIV prevention. The interview data indicate that the institutions take a stance of “conservative innovation,” weighing their role as keepers of morality and religious tradition against the changing needs of their communities and then adjusting their practices or positions incrementally (to varying degrees) to stay responsive and relevant. PMID:16255643

Chemical engineering challenges and investment opportunities in sustainable energy.

PubMed

Heller, Adam

2008-01-01

The chemical and energy industries are transforming as they adjust to the new era of high-priced petroleum and severe global warming. As a result of the transformation, engineering challenges and investment opportunities abound. Rapid evolution and fast growth are expected in cathode and anode materials as well as polymeric electrolytes for vehicular batteries and in high-performance polymer-ceramic composites for wind turbines, fuel-efficient aircraft, and lighter and safer cars. Unique process-engineering opportunities exist in sand-oil, coal, and possibly also shale liquefaction to produce transportation fuel; and also in genetic engineering of photosynthesizing plants and other organisms for their processing into high-performance biodegradable polymers and high-value-added environmentally friendly chemicals. Also, research on the feasibility of mitigation of global warming through enhancement of CO(2) uptake by the southern oceans by fertilization with trace amounts of iron is progressing. Because chemical engineers are uniquely well trained in mathematical modeling of mass transport, flow, and mixing, and also in cost analysis, they are likely to join the oceanographers and marine biologists in this important endeavor.

Older Workers and Federal Work Programs: The Korean Senior Employment Program (KSEP).

PubMed

Choi, Eunhee

2016-01-01

Federal older worker programs are attracting attention due to the growing number of older workers across the world. They are uniquely situated to provide out-of-market work opportunities to older job seekers, who often find their age a barrier to securing desirable jobs. In 2004, the Korean government established its own program, the Korean Senior Employment Program (KSEP); however, literature for international readers on this innovative program is lacking. Thus, this article aims to provide an in-depth description of KSEP and a brief comparison between the Senior Community Service Employment Program in the U.S. and KSEP. The unique characteristics of KSEP include having the dual program foci on supplemental income and social participation; expanding work opportunities in the private sector beyond community-based jobs; accepting participants who are financially disadvantaged as well as those with a high desire for social participation regardless of their income; and broadening work opportunities for those with professional skills beyond repetitive, simple, and temporary jobs. This article may offer helpful insights to older worker advocates from various countries in creating or modifying their programs.

Semi-transparent solar cells

NASA Astrophysics Data System (ADS)

Sun, J.; Jasieniak, J. J.

2017-03-01

Semi-transparent solar cells are a type of technology that combines the benefits of visible light transparency and light-to-electricity conversion. One of the biggest opportunities for such technologies is in their integration as windows and skylights within energy-sustainable buildings. Currently, such building integrated photovoltaics (BIPV) are dominated by crystalline silicon based modules; however, the opaque nature of silicon creates a unique opportunity for the adoption of emerging photovoltaic candidates that can be made truly semi-transparent. These include: amorphous silicon-, kesterite-, chalcopyrite-, CdTe-, dye-sensitized-, organic- and perovskite- based systems. For the most part, amorphous silicon has been the workhorse in the semi-transparent solar cell field owing to its established, low-temperature fabrication processes. Excitement around alternative classes, particularly perovskites and the inorganic candidates, has recently arisen because of the major efficiency gains exhibited by these technologies. Importantly, each of these presents unique opportunities and challenges within the context of BIPV. This topic review provides an overview into the broader benefits of semi-transparent solar cells as building-integrated features, as well as providing the current development status into all of the major types of semi-transparent solar cells technologies.

The International Space Station Research Opportunities and Accomplishments

NASA Technical Reports Server (NTRS)

Alleyne, Camille W.

2011-01-01

In 2010, the International Space Station (ISS) construction and assembly was completed to become a world-class scientific research laboratory. We are now in the era of utilization of this unique platform that facilitates ground-breaking research in the microgravity environment. There are opportunities for NASA-funded research; research funded under the auspice of the United States National Laboratory; and research funded by the International Partners - Japan, Europe, Russia and Canada. The ISS facilities offer an opportunity to conduct research in a multitude of disciplines such as biology and biotechnology, physical science, human research, technology demonstration and development; and earth and space science. The ISS is also a unique resource for educational activities that serve to motivate and inspire students to pursue careers in Science, Technology, Engineering and Mathematics. Even though we have just commenced full utilization of the ISS as a science laboratory, early investigations are yielding major results that are leading to such things as vaccine development, improved cancer drug delivery methods and treatment for debilitating diseases, such as Duchenne's Muscular Dystrophy. This paper

A New Way of Using the Interactive Whiteboard in a High School Physics Classroom: A Case Study

NASA Astrophysics Data System (ADS)

Gregorcic, Bor; Etkina, Eugenia; Planinsic, Gorazd

2017-02-01

In recent decades, the interactive whiteboard (IWB) has become a relatively common educational tool in Western schools. The IWB is essentially a large touch screen, that enables the user to interact with digital content in ways that are not possible with an ordinary computer-projector-canvas setup. However, the unique possibilities of IWBs are rarely leveraged to enhance teaching and learning beyond the primary school level. This is particularly noticeable in high school physics. We describe how a high school physics teacher learned to use an IWB in a new way, how she planned and implemented a lesson on the topic of orbital motion of planets, and what tensions arose in the process. We used an ethnographic approach to account for the teacher's and involved students' perspectives throughout the process of teacher preparation, lesson planning, and the implementation of the lesson. To interpret the data, we used the conceptual framework of activity theory. We found that an entrenched culture of traditional white/blackboard use in physics instruction interferes with more technologically innovative and more student-centered instructional approaches that leverage the IWB's unique instructional potential. Furthermore, we found that the teacher's confidence in the mastery of the IWB plays a crucial role in the teacher's willingness to transfer agency within the lesson to the students.

Short-term memory stores organized by information domain.

PubMed

Noyce, Abigail L; Cestero, Nishmar; Shinn-Cunningham, Barbara G; Somers, David C

2016-04-01

Vision and audition have complementary affinities, with vision excelling in spatial resolution and audition excelling in temporal resolution. Here, we investigated the relationships among the visual and auditory modalities and spatial and temporal short-term memory (STM) using change detection tasks. We created short sequences of visual or auditory items, such that each item within a sequence arose at a unique spatial location at a unique time. On each trial, two successive sequences were presented; subjects attended to either space (the sequence of locations) or time (the sequence of inter item intervals) and reported whether the patterns of locations or intervals were identical. Each subject completed blocks of unimodal trials (both sequences presented in the same modality) and crossmodal trials (Sequence 1 visual, Sequence 2 auditory, or vice versa) for both spatial and temporal tasks. We found a strong interaction between modality and task: Spatial performance was best on unimodal visual trials, whereas temporal performance was best on unimodal auditory trials. The order of modalities on crossmodal trials also mattered, suggesting that perceptual fidelity at encoding is critical to STM. Critically, no cost was attributable to crossmodal comparison: In both tasks, performance on crossmodal trials was as good as or better than on the weaker unimodal trials. STM representations of space and time can guide change detection in either the visual or the auditory modality, suggesting that the temporal or spatial organization of STM may supersede sensory-specific organization.

Unique Regulatory Approach for Licensing the Port Hope Remediation Project in Canada - 13315

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kostova, M.; Howard, D.; Elder, P.

2013-07-01

The Port Hope remediation project is a part of a larger initiative of the Canadian Federal Government the Port Hope Area Initiative (PHAI) which is based upon a community proposal. The Government of Canada, through Natural Resources Canada (NRCan) is investing $1.28 billion over 10 years to clean up historic low-level radioactive waste in the Port Hope Area and to provide long-term safe management of the low-level radioactive wastes in the Port Hope Area. These wastes arose from the activities of a former Federal Crown Corporation (Eldorado Nuclear) and its private sector predecessors. In Canada, historic waste are defined asmore » low-level radioactive waste that was managed in a manner no longer considered acceptable, but for which the original producer cannot reasonably be held responsible or no longer exists and for which the Federal Government has accepted responsibility. In Canada, under the current regulatory framework, the environmental remediation is not considered as a distinct phase of the nuclear cycle. The regulatory approach for dealing with existing sites contaminated with radioactive residues is defined on the basis of risk and application of existing regulations. A unique regulatory approach was taken by the Canadian Nuclear Safety Commission (CNSC) to address the various licensing issues and to set out the requirements for licensing of the Port Hope Project within the current regulatory framework. (authors)« less

Quantum Opportunities and Challenges for Fundamental Sciences in Space

NASA Technical Reports Server (NTRS)

Yu, Nan

2012-01-01

Space platforms offer unique environment for and measurements of quantum world and fundamental physics. Quantum technology and measurements enhance measurement capabilities in space and result in greater science returns.

Innovation through developing consumers’ community. Part I: Innovation in action

NASA Astrophysics Data System (ADS)

Gălăţanu (Avram, E.; Avasilcăi, S.

2015-11-01

Technological changes and need for innovation represents the main concerns for organizational growth and profitability. However the main priority is still about achieving high performance through product development and consumers' engagement activities. As implementation of open innovation applications increased and value co — creation became well known and major process, companies were engaged into value co — innovation activities. From this point of view the need for joint efforts with consumers in product development arose. Thus the primary condition for an organization to be consumer centric is to define clear the vision and mission which reflects the common efforts for co — creation and diffusion of innovation. As Research & Development processes evolved and interest for innovative concepts and products arose, companies started to implement the specific instruments for consumers' attraction and engagement into design and product development. The digitalized innovation became the main source for establishing the direct communication with the consumers. In order to achieve organization growth, profitability and recognition, the companies should be aware of the innovation importance and the need for internal change. From this point of view, there is necessary to assess the organizational structures, to implement new policies and to establish strategic targets. Basically it is justified the need for platform occurrence and development. Based on case study of BMW Group, recognised leader in automotive industry for innovative concepts, there will be analysed main features within organizational context which promotes the innovation implementation. There will be provided the review of the BMW Group experience of innovation activities, main consumers' engagement strategies, the values which promote the consumer — centric product development, new opportunities assessment, major policies and concerns. The foreseen result is to understand how companies are adapting to the technical and innovation changes as the main criteria for future product development and consumers' engagement motivation through the platform — based communication.

Using Virtual and In-Person Engagement Opportunities to Connect K-12 Students, Teachers, and the Public With NASA Astromaterials Research and Exploration Science Assets

NASA Technical Reports Server (NTRS)

Graff, P.; Foxworth, S.; Luckey, M. K.; McInturff, B.; Mosie, A.; Runco, S.; Todd, N.; Willis, K. J.; Zeigler, R.

2017-01-01

Engaging K-12 students, teachers, and the public with NASA Astromaterials Research and Exploration Science (ARES) assets provides an extraordinary opportunity to connect audiences with authentic aspects unique to our nation's space program. NASA ARES has effectively engaged audiences with 1) Science, Technology, Engineering and Mathematics (STEM) experts, 2) NASA specialized facilities, and 3) NASA astromaterial samples through both virtual and in-person engagement opportunities. These engagement opportunities help connect local and national audiences with STEM role models, promote the exciting work being facilitated through NASA's Science Mission Directorate, and expose our next generation of scientific explorers to science they may be inspired to pursue as a future STEM career.

Unique and proforma birth plans: a qualitative exploration of midwives׳ experiences.

PubMed

Welsh, Joanne V; Symon, Andrew G

2014-07-01

birth plans detailing a woman׳s preferences for intrapartum care are a common feature in British maternity units, and are a means of encouraging the implementation of choice. Proforma versions may be incorporated routinely in antenatal case notes, or the woman may devise her own unique birth plan. Although women׳s views of birth plans have been explored, the views of midwives have not to date been evaluated. The growth of midwife-led units in the UK has highlighted different philosophies of care, some of which can be reflected in the different types of birth plan. Given the increasingly diverse nature of UK midwifery workplaces we set out to explore and compare the experience of midwives working in midwife-led and obstetric-led settings in relation to unique and proforma birth plans. qualitative study using focus groups of midwives in a midwife-led unit (MLU; n=5) and obstetric-led unit (OLU; n=4) in the East of England. We used an interpretative phenomenological analytical approach. three main themes arose from the data. Firstly, the term 'birth plan' can be misleading, and was criticised for encouraging the belief that birth can be 'planned'. In addition, midwives claimed that 'unique' birth plans, especially those influenced by some consumer advocacy groups, are becoming standardised in their rejection of policies and procedures and requests for intervention-free birth. Secondly, birth plans were a source of irritation for midwives in both groups, although the cause of the irritation differed between groups. Finally, it was found that midwives in both groups felt that birth plans put pressure on them, although again, the source of the pressure, and therefore the way in which midwives reacted to this pressure, differed between groups. the term 'birth plan' can be misleading and create false expectations. If 'unique' birth plans are becoming 'standardised' in the sense that they routinely request the same things, they are little different to proforma birth plans. Some midwives perceive pressure both from women and the wider multidisciplinary team as a result of birth plans, a perception that causes some irritation. Copyright © 2014 Elsevier Ltd. All rights reserved.

Enhanced mobility for aging populations using automated vehicles.

DOT National Transportation Integrated Search

2015-12-01

Automated vehicles (AV) offer a unique opportunity to improve the safety and efficiency of the transportation : system and enhance the mobility of aging and transportation disadvantaged populations simultaneously. : However, before this potential can...

Hope Grows with a Unique Partnership.

ERIC Educational Resources Information Center

Ducharme, Barbara Allegro

2002-01-01

Describes the Don Bosco project that involves representatives from a Minnesota school district and Rotary Clubs who are working with the Salesian Congregation in Costa Rica to provide education opportunities for all children. (JOW)

What Do You Teach Here: Staff Development

ERIC Educational Resources Information Center

Richardson, Thomas E.

1975-01-01

The author maintains that college students are a key to value diffusion in our society and that student personnel workers hold unique opportunities in value transmission to students and, hence, to society. (Author/HMV)

Metastable Eutectic Equilibrium in Natural Environments: Recent Developments and Research Opportunities

NASA Technical Reports Server (NTRS)

Rietmeijer, Fans J. M.; Nuth, Joseph A., II; Jablonska, Mariola; Karner, James M.

2000-01-01

Chemical ordering at metastable eutectics was recognized in non-equilibrium gas-to- solid condensation experiments to constrain 'silicate' dust formation in O-rich circumstellar environments. The predictable metastable eutectic behavior successfully predicted the observed ferromagnesiosilica, compositions of circumstellar dust, presolar and solar nebula grains in the matrix of the collected aggregate IDPs. Many of the experimentally determined metastable eutectic solids match the fundamental building blocks of common rock-forming layer silicates: this could have implications for the origin of Life. The physical conditions conducive to metastable eutectic behavior, i.e. high temperature and (ultra)fast quenching, lead to unique amorphous, typically nano- to micrometer-sized, materials. The new paradigm of metastable eutectic behavior opens the door to new and exciting research opportunities in uncovering the many implications of these unique amorphous and typically nano- to micrometer-sized, metastable eutectic materials.

Opportunities for Drell-Yan Physics at RHIC

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aschenauer, E.; Bland, L.; Crawford, H.

Drell-Yan (DY) physics gives the unique opportunity to study the parton structure of nucleons in an experimentally and theoretically clean way. With the availability of polarized proton-proton collisions and asymmetric d+Au collisions at the Relativistic Heavy Ion Collider (RHIC), we have the basic (and unique in the world) tools to address several fundamental questions in QCD, including the expected gluon saturation at low partonic momenta and the universality of transverse momentum dependent parton distribution functions. A Drell-Yan program at RHIC is tied closely to the core physics questions of a possible future electron-ion collider, eRHIC. The more than 80 participantsmore » of this workshop focused on recent progress in these areas by both theory and experiment, trying to address imminent questions for the near and mid-term future.« less

Applications of “Tender” Energy (1-5 keV) X-ray Absorption Spectroscopy in Life Sciences

DOE Office of Scientific and Technical Information (OSTI.GOV)

Northrup, Paul; Leri, Alessandra; Tappero, Ryan

The “tender” energy range of 1 to 5 keV, between the energy ranges of most “hard” (>5 keV) and “soft” (<1 keV) synchrotron X-ray facilities, offers some unique opportunities for synchrotron-based X-ray absorption fine structure spectroscopy in life sciences. In particular the K absorption edges of Na through Ca offer opportunities to study local structure, speciation, and chemistry of many important biological compounds, structures and processes. This is an area of largely untapped science, in part due to a scarcity of optimized facilities. Such measurements also entail unique experimental challenges. Lastly, this brief review describes the technique, its experimental challenges,more » recent progress in development of microbeam measurement capabilities, and several highlights illustrating applications in life sciences.« less

Building and measuring a high performance network architecture

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kramer, William T.C.; Toole, Timothy; Fisher, Chuck

2001-04-20

Once a year, the SC conferences present a unique opportunity to create and build one of the most complex and highest performance networks in the world. At SC2000, large-scale and complex local and wide area networking connections were demonstrated, including large-scale distributed applications running on different architectures. This project was designed to use the unique opportunity presented at SC2000 to create a testbed network environment and then use that network to demonstrate and evaluate high performance computational and communication applications. This testbed was designed to incorporate many interoperable systems and services and was designed for measurement from the very beginning.more » The end results were key insights into how to use novel, high performance networking technologies and to accumulate measurements that will give insights into the networks of the future.« less

Market potential and opportunities for commercialization of traditional meat products in North East Hill Region of India.

PubMed

Kadirvel, G; Banerjee, Bandita B; Meitei, Surajit; Doley, S; Sen, Arnab; Muthukumar, M

2018-02-01

The North Eastern (NE) India is renowned for its preference for animal-based food. This region is known for its traditional meat products. However, the popularity of these products remains confined to the specific community/location. The knowledge on the traditional preparation methods is generally passed across generations through practice and word of mouth. The traditional style of preparation and the specific ingredients added to each product makes them unique. In this review, an attempt has been made to identify the initiatives, opportunities, and market potential for commercialization of the traditional meat products. These unique features and properties of the traditional meat products have been highlighted. The commercialization of these products will enhance entrepreneurship development and ensure quality ethnic products to the consumer in the NE hill region of India.

Market potential and opportunities for commercialization of traditional meat products in North East Hill Region of India

PubMed Central

Kadirvel, G.; Banerjee, Bandita B.; Meitei, Surajit; Doley, S.; Sen, Arnab; Muthukumar, M.

2018-01-01

The North Eastern (NE) India is renowned for its preference for animal-based food. This region is known for its traditional meat products. However, the popularity of these products remains confined to the specific community/location. The knowledge on the traditional preparation methods is generally passed across generations through practice and word of mouth. The traditional style of preparation and the specific ingredients added to each product makes them unique. In this review, an attempt has been made to identify the initiatives, opportunities, and market potential for commercialization of the traditional meat products. These unique features and properties of the traditional meat products have been highlighted. The commercialization of these products will enhance entrepreneurship development and ensure quality ethnic products to the consumer in the NE hill region of India. PMID:29657390

Applications of “Tender” Energy (1-5 keV) X-ray Absorption Spectroscopy in Life Sciences

DOE PAGES

Northrup, Paul; Leri, Alessandra; Tappero, Ryan

2016-02-15

The “tender” energy range of 1 to 5 keV, between the energy ranges of most “hard” (>5 keV) and “soft” (<1 keV) synchrotron X-ray facilities, offers some unique opportunities for synchrotron-based X-ray absorption fine structure spectroscopy in life sciences. In particular the K absorption edges of Na through Ca offer opportunities to study local structure, speciation, and chemistry of many important biological compounds, structures and processes. This is an area of largely untapped science, in part due to a scarcity of optimized facilities. Such measurements also entail unique experimental challenges. Lastly, this brief review describes the technique, its experimental challenges,more » recent progress in development of microbeam measurement capabilities, and several highlights illustrating applications in life sciences.« less

Assessing Opportunities for Student Pharmacist Leadership Development at Schools of Pharmacy in the United States.

PubMed

Feller, Tara T; Doucette, William R; Witry, Matthew J

2016-06-25

Objective. To summarize student pharmacist leadership development opportunities delivered by pharmacy programs, to describe selected opportunities, and to assess how these opportunities meet leadership development competencies. Methods. A multi-method study was conducted that comprised a systematic content analysis of pharmacy education journals, pharmacy program websites, and telephone interviews with key informants, which included open-ended questions and scaled responses. Results. Review of six articles, 37 American Association of Colleges of Pharmacy (AACP) Annual Meeting abstracts, and 138 websites resulted in the identification of 191 leadership development opportunities. These consisted of courses, projects/programs, and events/speaker series. Interviews with 12 key informants detailed unique events that developed leadership competencies. Formal assessments of student leadership development were limited and primarily focused on informal feedback and course evaluations. Conclusion. Most US pharmacy programs offer their students an array of opportunities to develop leadership abilities. Pharmacy programs should consider expanding opportunities beyond elective courses, learn from the successes of others to implement new leadership development opportunities, and bolster the assessment of student leadership competencies and outcomes.

Assessing Opportunities for Student Pharmacist Leadership Development at Schools of Pharmacy in the United States

PubMed Central

Feller, Tara T.; Witry, Matthew J.

2016-01-01

Objective. To summarize student pharmacist leadership development opportunities delivered by pharmacy programs, to describe selected opportunities, and to assess how these opportunities meet leadership development competencies. Methods. A multi-method study was conducted that comprised a systematic content analysis of pharmacy education journals, pharmacy program websites, and telephone interviews with key informants, which included open-ended questions and scaled responses. Results. Review of six articles, 37 American Association of Colleges of Pharmacy (AACP) Annual Meeting abstracts, and 138 websites resulted in the identification of 191 leadership development opportunities. These consisted of courses, projects/programs, and events/speaker series. Interviews with 12 key informants detailed unique events that developed leadership competencies. Formal assessments of student leadership development were limited and primarily focused on informal feedback and course evaluations. Conclusion. Most US pharmacy programs offer their students an array of opportunities to develop leadership abilities. Pharmacy programs should consider expanding opportunities beyond elective courses, learn from the successes of others to implement new leadership development opportunities, and bolster the assessment of student leadership competencies and outcomes. PMID:27402982

Auditory and Vestibular Issues Related to Human Spaceflight

NASA Technical Reports Server (NTRS)

Danielson, Richard W.; Wood, Scott J.

2009-01-01

Human spaceflight provides unique opportunities to study human vestibular and auditory systems. This session will discuss 1) vestibular adaptive processes reflected by pronounced perceptual and motor coordination problems during, and after, space missions; 2) vestibular diagnostic and rehabilitative techniques (used to promote recovery after living in altered gravity environments) that may be relevant to treatment of vestibular disorders on earth; and 3) unique acoustical challenges to hearing loss prevention and crew performance during spaceflight missions.

Executive summary: conference on Dietary Supplement Use in the Elderly--proceedings of the conference held January 14-15, 2003, Natcher Auditorium, National, Institutes of Health, Bethesda, MD.

PubMed

2004-04-01

Several issues prompted the need for this conference. Among these were the reported high prevalence (> 50%) of use of supplements among individuals over 50 years of age, inadequate scientific evidence supporting the safety and benefits of use among these individuals, and a report issued by the General Accounting Office (GAO) in 2001. This GAO report entitled "Health Products for Seniors: 'Anti-Aging' Products Pose Potential for Physical and Economic Harm," arose from concerns among legislators that seniors were spending money from their limited incomes on products that were not only ineffective but also potentially harmful. The conference was organized around three sessions to address the issues highlighted above, which were usage of dietary supplements among the elderly, age-related changes and issues that affect the use of supplements, and the evidence base supporting the use of supplements in disease prevention and health maintenance. Each session was followed by a panel discussion. This Executive Summary is organized around the three major discussion topics. The summary does not explicitly follow the order of the conference presentations; rather it is intended to capture and examine the current research gaps in knowledge and identify future research opportunities. These research opportunities, as expressed by the conference speakers, panelists, and attendees are summarized at the end of this paper under five thematic areas: usage behaviors, methodology, pre-clinical studies and clinical studies, informational databases, and education and dissemination.

Agricultural management affects evolutionary processes in a migratory songbird

USGS Publications Warehouse

Perlut, N.G.; Freeman-Gallant, C. R.; Strong, A.M.; Donovan, T.M.; Kilpatrick, C.W.; Zalik, N.J.

2008-01-01

Hay harvests have detrimental ecological effects on breeding songbirds, as harvesting results in nest failure. Importantly, whether harvesting also affects evolutionary processes is not known. We explored how hay harvest affected social and genetic mating patterns, and thus, the overall opportunity for sexual selection and evolutionary processes for a ground-nesting songbird, the Savannah sparrow (Passerculus sandwichensis). On an unharvested field, 55% of females were in polygynous associations, and social polygyny was associated with greater rates of extra-pair paternity (EPP). In this treatment, synchrony explained variation in EPP rates, as broods by more synchronous females had more EPP than broods by asynchronous females. In contrast, on a harvested field, simultaneous nest failure caused by haying dramatically decreased the overall incidence of EPP by increasing the occurrence of social monogamy and, apparently, the ability of polygynous males to maintain paternity in their own nests. Despite increased social and genetic monogamy, these haying-mediated changes in mating systems resulted in greater than twofold increase in the opportunity for sexual selection. This effect arose, in part, from a 30% increase in the variance associated with within-pair fertilization success, relative to the unharvested field. This effect was caused by a notable increase (+110%) in variance associated with the quality of social mates following simultaneous nest failure. Because up to 40% of regional habitat is harvested by early June, these data may demonstrate a strong population-level effect on mating systems, sexual selection, and consequently, evolutionary processes. ?? 2008 The Authors.

CLEAN PRODUCTION WITH MEMBRANE TECHNOLOGY

EPA Science Inventory

Membrane processes, because of unique, specialized, and cost-effective applications, have the potential of playing a significant role in preventing pollution from occurring in manufacturing plans. Opportunities are seen in resource recovery, species purification, and energy sav...

Using Naturalistic Data to Develop Simulator Scenarios

DOT National Transportation Integrated Search

2017-11-01

The establishment of large naturalistic driver data sets, most recently the Strategic : Highway Research Program 2 (SHRP2), provides unique opportunities to observe driver : behavior under real-world conditions. In order to better understand the rela...

EPA Policy for Innovative Environmental Technologies at Federal Facilities

EPA Pesticide Factsheets

This is a memo from the EPA Administrator, regarding the unique opportunities for the development and application of innovative technologies and approaches to pollution prevention, source control, site investigation, and remediation at Federal facilities.

How to Spend Your Summer Vacation.

ERIC Educational Resources Information Center

Louviere, James P.; Mungas, Jenny

1994-01-01

A high school senior describes her adventures as part of an eight-week glacier expedition in Alaska and British Columbia. Also includes information on how to obtain unique summer enrichment opportunities for teachers and students. (ZWH)

Infrasound Observations from the Source Physics Experiment (Tests 1 and 2) at the Nevada National Security Site

DTIC Science & Technology

2012-09-01

series of explosions, we have the unique and rare opportunity to study infrasound generated by a well-characterized source from the same borehole ...opportunity to study infrasound generated by a well-characterized source from the same borehole . This reduces the number of variables that must be...experiment is to study the seismic waves generated from explosions in both damaged and undamaged rock and that the observed infrasound is a

Harry Potter and the Upcoming Venus-Jupiter Conjunction: A Unique Outreach Opportunity

NASA Astrophysics Data System (ADS)

Larsen, K.

2008-09-01

As we prepare for the International Year of Astronomy 2009 (IYA2009), we should be on the lookout for celestial events which we can use not only to popularise the IYA2009 and practise our outreach skills, but which also have natural connections to popular culture. The Venus-Jupiter conjunction this autumn is such an opportunity, given several direct connections to the use of astronomy in J. K. Rowling's famous Harry Potter universe.

Opportunities and challenges for seaweed in the biobased economy.

PubMed

van Hal, Jaap W; Huijgen, W J J; López-Contreras, A M

2014-05-01

The unique chemical composition of seaweeds and their fast growth rates offer many opportunities for biorefining. In this article we argue that cascading biorefinery valorization concepts are viable alternatives to only using seaweeds as carbohydrate sources for the fermentative production of biofuels. However, many challenges remain with respect to use of seaweeds for chemical production, such as the large seasonal variation in the chemical composition of seaweeds. Copyright © 2014 Elsevier Ltd. All rights reserved.

Electrophysiological monitoring during basilar aneurysm operation.

PubMed

Little, J R; Lesser, R P; Luders, H

1987-03-01

Intraoperative brain stem auditory evoked potential (BAEP) and somatosensory evoked potential (SEP) monitoring was evaluated in 16 patients each undergoing intracranial operation for basilar artery aneurysm. The 16 patients had 18 posterior circulation aneurysms, including 2 patients with 2 aneurysms. Fourteen aneurysms arose from the rostral basilar artery, 2 arose from the midbasilar artery, 1 arose from the vertebrobasilar junction, and 1 arose from the proximal segment of the posterior cerebral artery. Five aneurysms were classified as giant (i.e., greater than 25 mm), and 5 aneurysms were large (i.e., 15 to 25 mm). Ten patients had BAEP and SEP monitoring, 4 had BAEP monitoring only, and 2 had SEP monitoring only. Two patients showed significant abnormalities during operation, including 1 patient with transient changes in the BAEP when the lower pons and the 8th cranial nerve were retracted. Another patient had progressive increases in latency and decreases in amplitude and subsequent loss of the SEP cortical components during a period of intermittent temporary rostral basilar artery occlusion. Wave P13 was also lost during that period. The cortical components as well as Wave P13 returned after circulation was restored. The BAEPs were unchanged in the same patient during the period of temporary basilar artery occlusion. Fourteen patients had no significant abnormalities. There were no consistent changes during the various stages of operation. BAEP and SEP monitoring failed to identify ischemic events in 4 patients with neurological findings of brain stem ischemia immediately after operation (i.e., 25% false-negative studies).(ABSTRACT TRUNCATED AT 250 WORDS)

A De Novo Deletion in the Regulators of Complement Activation Cluster Producing a Hybrid Complement Factor H/Complement Factor H-Related 3 Gene in Atypical Hemolytic Uremic Syndrome.

PubMed

Challis, Rachel C; Araujo, Geisilaine S R; Wong, Edwin K S; Anderson, Holly E; Awan, Atif; Dorman, Anthony M; Waldron, Mary; Wilson, Valerie; Brocklebank, Vicky; Strain, Lisa; Morgan, B Paul; Harris, Claire L; Marchbank, Kevin J; Goodship, Timothy H J; Kavanagh, David

2016-06-01

The regulators of complement activation cluster at chromosome 1q32 contains the complement factor H (CFH) and five complement factor H-related (CFHR) genes. This area of the genome arose from several large genomic duplications, and these low-copy repeats can cause genome instability in this region. Genomic disorders affecting these genes have been described in atypical hemolytic uremic syndrome, arising commonly through nonallelic homologous recombination. We describe a novel CFH/CFHR3 hybrid gene secondary to a de novo 6.3-kb deletion that arose through microhomology-mediated end joining rather than nonallelic homologous recombination. We confirmed a transcript from this hybrid gene and showed a secreted protein product that lacks the recognition domain of factor H and exhibits impaired cell surface complement regulation. The fact that the formation of this hybrid gene arose as a de novo event suggests that this cluster is a dynamic area of the genome in which additional genomic disorders may arise. Copyright © 2016 by the American Society of Nephrology.

A surgical sabbatical in France.

PubMed

Sutherland, F; Launois, B

2000-06-01

During my stay in France I had the unique opportunity to meet surgical professors from all over the world and made many friends and contacts in the field of hepatobiliary surgery. Brittany is a beautiful province of France, having unique way of life and approach to social and societal problems. The cultural enrichment that I received from my year there will last a lifetime, as well the many fond memories of the people, the culinary delights and the spectacular seashore.

Post-Conflict Returnee Reintegration: A Case Study of South Sudan and the Livelihood Approach

DTIC Science & Technology

2013-09-01

Gabaudan argues for the need of relief agencies to bridge this humanitarian and development gap .2 While South Sudan is not a unique case highlighting a...state suffering from a refugee and IDP crisis, every crisis is unique and may yield valuable lessons. The consequences of war have been profound for...research does, however, provides an opportunity to analyze the dynamics of refugee assistance as they unfold, highlighting the gap between providing short

Synthetic biology of cyanobacteria: unique challenges and opportunities

PubMed Central

Berla, Bertram M.; Saha, Rajib; Immethun, Cheryl M.; Maranas, Costas D.; Moon, Tae Seok; Pakrasi, Himadri B.

2013-01-01

Photosynthetic organisms, and especially cyanobacteria, hold great promise as sources of renewably-produced fuels, bulk and specialty chemicals, and nutritional products. Synthetic biology tools can help unlock cyanobacteria's potential for these functions, but unfortunately tool development for these organisms has lagged behind that for S. cerevisiae and E. coli. While these organisms may in many cases be more difficult to work with as “chassis” strains for synthetic biology than certain heterotrophs, the unique advantages of autotrophs in biotechnology applications as well as the scientific importance of improved understanding of photosynthesis warrant the development of these systems into something akin to a “green E. coli.” In this review, we highlight unique challenges and opportunities for development of synthetic biology approaches in cyanobacteria. We review classical and recently developed methods for constructing targeted mutants in various cyanobacterial strains, and offer perspective on what genetic tools might most greatly expand the ability to engineer new functions in such strains. Similarly, we review what genetic parts are most needed for the development of cyanobacterial synthetic biology. Finally, we highlight recent methods to construct genome-scale models of cyanobacterial metabolism and to use those models to measure properties of autotrophic metabolism. Throughout this paper, we discuss some of the unique challenges of a diurnal, autotrophic lifestyle along with how the development of synthetic biology and biotechnology in cyanobacteria must fit within those constraints. PMID:24009604

Assessment of bioenergy crop production along North Carolina right-of-ways.

DOT National Transportation Integrated Search

2012-04-01

The production of flowering oilseeds along highway right-of-ways provides land managers with a unique opportunity to meet safety and vegetation management objectives while providing enhance roadside aesthetics for motorists. Additionally, these opera...

Visiting Scholars Program | Frederick National Laboratory for Cancer Research

Cancer.gov

The Visiting Scholars Program (VSP) provides a unique opportunity for scientists to collaborate with the Frederick National Laboratory for Cancer Research (FNLCR), the only federal national laboratory in the United States devoted exclusively to b

75 FR 14424 - Marine Mammals; File No. 87-1743

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-25

... number of weaned pups weighed, measured, and tagged in order to study the effects of a current El Ni... conditions related to an El Ni[ntilde]o event represent a unique research opportunity to study climactic...

76 FR 69311 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing and Immediate Effectiveness of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-08

...'') and broker-dealers increased authority and flexibility to offer new and unique market data to..., providing virtually limitless opportunities for entrepreneurs who wish to produce and distribute their own...

Developing a remote practice office.

PubMed

D'Elia, V L

1987-11-01

Remote practice offices (RPOs) offer unique opportunities for hospitals and physicians to increase market share from targeted areas where previously only limited demand existed. This article discusses the benefits and explores the fundamentals of developing a remote practice office.

The Gateway Garden — A Prototype Food Production Facility for Deep Space Exploration

NASA Astrophysics Data System (ADS)

Fritsche, R. F.; Romeyn, M. W.; Massa, G.

2018-02-01

CIS-lunar space provides a unique opportunity to perform deep space microgravity crop science research while also addressing and advancing food production technologies that will be deployed on the Deep Space Transport.

Metastable Eutectic Equilibrium in Natural Environments: Recent Development and Research Opportunities

NASA Technical Reports Server (NTRS)

Rietmeijer, Frans J. M.; Nuth, Joseph A., III; Jablonska, Mariola; Karner, James M.

2000-01-01

Chemical ordering at metastable eutectics was recognized in non-equilibrium gas-to- solid condensation experiments to constrain 'silicate' dust formation in O-rich circumstellar environments. The predictable metastable eutectic behavior successfully predicted the observed ferromagnesiosilica compositions of circumstellar dust presolar and solar nebula grains in the matrix of the collected aggregate IDPs (Interplanetary Dust Particles). Many of the experimentally determined metastable eutectic solids match the fundamental building blocks of common rock-forming layer silicates: this could have implications for the origin of Life. The physical conditions conducive to metastable eutectic behavior, i.e. high temperature and (ultra) fast quenching, lead to unique amorphous, typically nano- to micrometer-sized, materials. The new paradigm of metastable eutectic behavior opens the door to new and exciting research opportunities in uncovering the many implications of these unique amorphous, and typically nano-to micrometer-sized, metastable eutectic materials.

New design opportunities with OVI

NASA Astrophysics Data System (ADS)

Bleikolm, Anton F.

1998-04-01

Optically Variable Ink (OVITM) chosen for its unique colour shifting properties is applied to the currencies of more than 50 countries. An significant colour difference at viewing angles of 90 degrees and 30 degrees respectively makes colour copying impossible. New manufacturing techniques for the interference pigment (OVP) provide ever better cost/performance ratios. Screen printing presses newly available on the market guarantee production speeds of 8000 sheets/hour or 130 meters/minute in the case of web printing, perfectly in line with the traditional equipment for manufacturing of currency. Specifically developed ink formulations allow UV-curing at high speed or oxidative drying to create highly mechanically and chemically resistant colour shifting prints. The unique colour shifting characteristics together with overprinting in intaglio give design opportunities providing the best protection against colour copying or commercial reprint. Specific designs of OVP together with high security ingredients allow the formulation of machine readable optically variable inks useful for the authentication and sorting of documents.

State of the art: dual-energy CT of the abdomen.

PubMed

Marin, Daniele; Boll, Daniel T; Mileto, Achille; Nelson, Rendon C

2014-05-01

Recent technologic advances in computed tomography (CT)--enabling the nearly simultaneous acquisition of clinical images using two different x-ray energy spectra--have sparked renewed interest in dual-energy CT. By interrogating the unique characteristics of different materials at different x-ray energies, dual-energy CT can be used to provide quantitative information about tissue composition, overcoming the limitations of attenuation-based conventional single-energy CT imaging. In the past few years, intensive research efforts have been devoted to exploiting the unique and powerful opportunities of dual-energy CT for a variety of clinical applications. This has led to CT protocol modifications for radiation dose reduction, improved diagnostic performance for detection and characterization of diseases, as well as image quality optimization. In this review, the authors discuss the basic principles, instrumentation and design, examples of current clinical applications in the abdomen and pelvis, and future opportunities of dual-energy CT.

Epigenetics, eh! A meeting summary of the Canadian Conference on Epigenetics.

PubMed

Rodenhiser, David I; Bérubé, Nathalie G; Mann, Mellissa R W

2011-10-01

In May 2011, the Canadian Conference on Epigenetics: Epigenetics Eh! was held in London, Canada. The objectives of this conference were to showcase the breadth of epigenetic research on environment and health across Canada and to provide the catalyst to develop collaborative Canadian epigenetic research opportunities, similar to existing international epigenetic initiatives in the US and Europe. With ten platform sessions and two sessions with over 100 poster presentations, this conference featured cutting-edge epigenetic research, presented by Canadian and international principal investigators and their trainees in the field of epigenetics and chromatin dynamics. An EpigenART competition included ten artists, creating a unique opportunity for artists and scientists to interact and explore their individual interpretations of this scientific discipline. The conference provided a unique venue for a significant cross-section of Canadian epigenetic researchers from diverse disciplines to meet, interact, collaborate and strategize at the national level.

Human space exploration the next fifty years.

PubMed

Williams, David R; Turnock, Matthew

2011-06-01

Preparation for the fiftieth anniversary of human spaceflight in the spring of 2011 provides the space faring nations with an opportunity to reflect on past achievements as well as consider the next fifty years of human spaceflight. The International Space Station is a unique platform for long duration life science research that will play a critical role in preparing for future human space exploration beyond low earth orbit. Some feel the future path back to the Moon and on to Mars may be delayed with the current commitment of the United States to support the development of human-rated commercial spacecraft. Others see this as a unique opportunity to leverage the capability of the private sector in expanding access to space exploration. This article provides an overview of the past achievements in human spaceflight and discusses future missions over the next fifty years and the role space medicine will play in extending the time-distance constant of human space exploration.

Commercial opportunities utilizing the International Space Station

NASA Astrophysics Data System (ADS)

Kearney, Michael E.; Mongan, Phil; Overmyer, Carolyn M.; Jackson, Kenneth

1998-01-01

The International Space Station (ISS) has the unique capability of providing a low-g environment for both short- and long-duration experimentation. This environment can provide a unique and competitive research capability to industry; but until recently, utilization of this environment by the private sector has been limited if not totally unavailable. NASA has recently expressed an interest in the commercial development of space and this is now an integral part of the Agency's enabling legislation through the Space Act. NASA's objective is to foster the use of the space environment for the development of commercial products and processes. Through alliances and agreements with several commercial companies and universities, SPACEHAB, Inc., has built a comprehensive package of services designed to provide low-cost reliable access to space for experimenters. These services provide opportunities to support engineering test beds for materials exposure analysis, to mitigate structural failures as observed on the Hubble Space Telescope; materials processing, remote sensing; space environment definition; and electronic experiments. The intent of this paper is to identify commercial opportunities for utilizing the International Space Station and provide examples of several facilities currently being designed and manufactured by commercial companies with the purpose of providing access to the space environment for commercial users.

The detection and mapping of oil on a marshy area by a remote luminescent sensor

USGS Publications Warehouse

McFarlane, C.; Watson, R.D.

2005-01-01

Airborne remote sensing can be a cost-effective method for monitoring pollutants in large areas such as occur in oil spills. An opportunity to test a particular method arose when a well ruptured and for 23 days spewed a 90-meter fountain of oil into the air, dispersing the oil over a wide area. The method tested was an airborne luminescence detector with a Fraunhofer Line Discriminator (FLD) which was flown over the affected area 41 days after the well was capped to obtain a map or the deposition pattern. To calibrate the system, samples of Spartina (wire grass) and Phragmites (common reed) were collected from the contaminated area and the oil residues were eluted in cyclohexane and quantitatively analyzed in a fluorescence photometer. Good correlation was observed between the remote sensor (FLD) and the laboratory analysis. Isopleths defining the deposition pattern of oil were drawn from the remote sensing information. A discussion will be presented on the feasibility of using this instrument for similar contamination incidents for cleanup and damage assessment.

Integrating PCR theory and bioinformatics into a research-oriented primer design exercise.

PubMed

Robertson, Amber L; Phillips, Allison R

2008-01-01

Polymerase chain reaction (PCR) is a conceptually difficult technique that embodies many fundamental biological processes. Traditionally, students have struggled to analyze PCR results due to an incomplete understanding of the biological concepts (theory) of DNA replication and strand complementarity. Here we describe the design of a novel research-oriented exercise that prepares students to design DNA primers for PCR. Our exercise design includes broad and specific learning goals and assessments of student performance and perceptions. We developed this interactive Primer Design Exercise using the principles of scientific teaching to enhance student understanding of the theory behind PCR and provide practice in designing PCR primers to amplify DNA. In the end, the students were more poised to troubleshoot problems that arose in real experiments using PCR. In addition, students had the opportunity to utilize several bioinformatics tools to gain an increased understanding of primer quality, directionality, and specificity. In the course of this study many misconceptions about DNA replication during PCR and the need for primer specificity were identified and addressed. Students were receptive to the new materials and the majority achieved the learning goals.

Violence in the Brazilian favelas and the role of the police.

PubMed

Huguet, Clarissa; Szabó de Carvalho, Ilona

2008-01-01

Institutions should normally have an integrative influence. The family, for example, has the task of protecting and giving socio-emotional support to children, and schools should prepare young people for their future. Ideally the common goal of all of society's institutions is to secure the integration of youth and prevent or intervene against deviant behavior. But sometimes institutions provoke or even cause juvenile delinquency. The article discusses institutional influences and the role of the police in the criminal and violent situation in the favelas of Rio de Janeiro.Starting with an overview of the origins and the development of violence, crime, and drug trafficking in the favelas, the authors show how these slums arose. Their analysis examines the lack of a state presence with an integration policy to avoid social disintegration. Instead of social integration policy, there is a dual approach that both controls and produces violence. The article also presents the first results of a government attempt in 2000 to introduce a new police unit to stop the violence and improve the social opportunity structure of the residents of the favelas, especially young people.

Early Pottery Making in Northern Coastal Peru. Part II: Field Firing Experiments

NASA Astrophysics Data System (ADS)

Shimada, I.; Goldstein, D.; Sosa, J.; Wagner, U.

2003-09-01

We present data from three seasons of experimental field work designed to recreate ancient Andean coastal ceramic firing techniques. Based on the recent discovery of two different archaeological ceramic production sites in the La Leche river valley of northern coastal Peru, the opportunity arose to apply Mössbauer spectroscopy and other analytical methods to reconstruct ancient firing procedures. Two sets of firings took place in 1993 and 1997 in Batán Grande using a partially restored Formative kiln from about 800 BC, local hardwood and cow dung as fuel. A third experiment followed in 2000 after the discovery of a Middle Sicán ceramics workshop in use between ca. AD 950 and 1050 at Huaca Sialupe, where an exact replica of an ancient kiln was built from local clay, and fired with local wood and cow dung. Additionally, inverted urns found at Huaca Sialupe were tested for their potential use as furnaces for metal working. Mössbauer spectroscopy was used to compare the physical and chemical state of specimens produced in the field experiments with ancient ceramics and with specimens produced in controlled laboratory experiments.

Spatial storage effect promotes biodiversity during adaptive radiation.

PubMed

Tan, Jiaqi; Rattray, Jennifer B; Yang, Xian; Jiang, Lin

2017-07-12

Many ecological communities are enormously diverse. Variation in environmental conditions over time and space provides opportunities for temporal and spatial storage effects to operate, potentially promoting species coexistence and biodiversity. While several studies have provided empirical evidence supporting the significance of the temporal storage effect for coexistence, empirical tests of the role of the spatial storage effect are rare. In particular, we know little about how the spatial storage effect contributes to biodiversity over evolutionary timescales. Here, we report the first experimental study on the role of the spatial storage effect in the maintenance of biodiversity in evolving metacommunities, using the bacterium Pseudomonas fluorescens SBW25 as a laboratory model of adaptive radiation. We found that intercommunity spatial heterogeneity promoted phenotypic diversity of P. fluorescens in the presence of dispersal among local communities, by allowing the spatial storage effect to operate. Mechanistically, greater niche differences among P. fluorescens phenotypes arose in metacommunities with intercommunity spatial heterogeneity, facilitating negative frequency-dependent selection, and thus, the coexistence among P. fluorescens phenotypes. These results highlight the importance of the spatial storage effect for biodiversity over evolutionary timescales. © 2017 The Author(s).

The big bang? An eventful year in workers' compensation.

PubMed

Guidotti, Tee L

2006-01-01

Workers' compensation in the past two years has been dominated by events in California, which have been so fundamental as to merit the term big bang. Passage of Senate Bill 899 has led to a comprehensive program of reform in access to medical care, access to rehabilitation services, temporary and permanent disability, evidence-based management, dispute resolution, and system innovation. Two noteworthy developments thus arose: a new requirement for apportionment by cause in causation analysis, and the adoption of evidence-based criteria for impairment assessment, treatment guidelines, and, soon, utilization review. Elsewhere in the United States, changes were modest, but extensive legislative activity in Texas suggests that Texas will be next to make major changes. In Canada, the Workers' Compensation Board of British Columbia has adopted an ambitious strategic initiative, and there is a Canadawide movement to establish presumption for certain diseases in firefighters. Suggestions for future directions include an increased emphasis on prevention, integration of programs, worker participation, enhancing the expertise of health care professionals, evidence-based management, process evaluation, and opportunities for innovation.

Examining the Role of Leadership in an Undergraduate Biology Institutional Reform Initiative

PubMed Central

Matz, Rebecca L.; Jardeleza, Sarah E.

2016-01-01

Undergraduate science, technology, engineering, and mathematics (STEM) education reform continues to be a national priority. We studied a reform process in undergraduate biology at a research-intensive university to explore what leadership issues arose in implementation of the initiative when characterized with a descriptive case study method. The data were drawn from transcripts of meetings that occurred over the first 2 years of the reform process. Two literature-based models of change were used as lenses through which to view the data. We find that easing the burden of an undergraduate education reform initiative on faculty through articulating clear outcomes, developing shared vision across stakeholders on how to achieve those outcomes, providing appropriate reward systems, and ensuring faculty have ample opportunity to influence the initiative all appear to increase the success of reform. The two literature-based models were assessed, and an extended model of change is presented that moves from change in STEM instructional strategies to STEM organizational change strategies. These lessons may be transferable to other institutions engaging in education reform. PMID:27856545

Recent speciation in the Indo-West Pacific: rapid evolution of gamete recognition and sperm morphology in cryptic species of sea urchin.

PubMed Central

Landry, C; Geyer, L B; Arakaki, Y; Uehara, T; Palumbi, Stephen R

2003-01-01

The rich species diversity of the marine Indo-West Pacific (IWP) has been explained largely on the basis of historical observation of large-scale diversity gradients. Careful study of divergence among closely related species can reveal important new information about the pace and mechanisms of their formation, and can illuminate the genesis of biogeographic patterns. Young species inhabiting the IWP include urchins of the genus Echinometra, which diverged over the past 1-5 Myr. Here, we report the most recent divergence of two cryptic species of Echinometra inhabiting this region. Mitochondrial cytochrome oxidase 1 (CO1) sequence data show that in Echinometra oblonga, species-level divergence in sperm morphology, gamete recognition proteins and gamete compatibility arose between central and western Pacific populations in the past 250 000 years. Divergence in sperm attachment proteins suggests rapid evolution of the fertilization system. Divergence of sperm morphology may be a common feature of free-spawning animals, and offers opportunities to simultaneously understand genetic divergence, changes in protein expression patterns and morphological evolution in traits directly related to reproductive isolation. PMID:12964987

Flight Test of a Technology Transparent Light Concentration Panel on SMEX/WIRE

NASA Technical Reports Server (NTRS)

Stern, Theodore G.; Lyons, John

2000-01-01

A flight experiment has demonstrated a modular solar concentrator that can be used as a direct substitute replacement for planar photovoltaic panels in spacecraft solar arrays. The Light Concentrating Panel (LCP) uses an orthogrid arrangement of composite mirror strips to form an array of rectangular mirror troughs that reflect light onto standard, high-efficiency solar cells at a concentration ratio of approximately 3:1. The panel area, mass, thickness, and pointing tolerance has been shown to be similar to a planar array using the same cells. Concentration reduces the panel's cell area by 2/3, which significantly reduces the cost of the panel. An opportunity for a flight experiment module arose on NASA's Small Explorer / Wide-Field Infrared Explorer (SMEX/WIRE) spacecraft, which uses modular solar panel modules integrated into a solar panel frame structure. The design and analysis that supported implementation of the LCP as a flight experiment module is described. Easy integration into the existing SMEX-LITE wing demonstrated the benefits of technology transparency. Flight data shows the stability of the LCP module after nearly one year in Low Earth Orbit.

Go Home, Med Student: Comics as Visual Media for Students' Traumatic Medical Education Experiences.

PubMed

Monk, Jeffrey

2018-02-01

A comic created by a medical student allows the reader to share the student's own unique perception of the medical education experience. Through the process of comic creation, medical students have opportunities to gain insight into how their relationships with patients and supervising physicians have shaped the physician they will become. The comic itself can be a safe space for expression and provides an opportunity for students and educators to share experiences. © 2018 American Medical Association. All Rights Reserved.

NASA's space physics theory program - An opportunity for collaboration

NASA Technical Reports Server (NTRS)

Vinas, Adolfo F.

1990-01-01

The field of theoretical space physics offers a unique opportunity to Latin American scientists for collaborative participation in NASA programs where the greatly increased complexity of both experimental observations and theoretical simulations requires in-depth comparisons between theory and observational data. The key problem areas identified by NASA for aggressive work in the decade of the 1990s are the nature of flows and turbulence, acceleration and transport of particles, the coupling of microphysics and macrophysics, the coupling of local and global dynamics, and nonclassical plasmas.

Using NASA-Unique Lunar Sample Disks and Resources to Inspire and Promote Scientific Inquiry

NASA Technical Reports Server (NTRS)

Allen, J.; Graff, P. V.; Willis, K. J.; Runco, S.

2014-01-01

The opportunity for educators and students across the nation to hold precious, NASA lunar samples in their hands and examine materials brought back by astronauts during the Apollo era is an experience and memory that can last a lifetime. Combine that experience with the opportunity to be engaged with hands-on activities that promote scientific inquiry and an understanding of the importance of these samples...now you are preparing our nation's future scientific explorers.

Frontier Aerospace Opportunities

NASA Technical Reports Server (NTRS)

Bushnell, Dennis M.

2014-01-01

Discussion and suggested applications of the many ongoing technology opportunities for aerospace products and missions, resulting in often revolutionary capabilities. The, at this point largely unexamined, plethora of possibilities going forward, a subset of which is discussed, could literally reinvent aerospace but requires triage of many possibilities. Such initial upfront homework would lengthen the Research and Development (R&D) time frame but could greatly enhance the affordability and performance of the evolved products and capabilities. Structural nanotubes and exotic energetics along with some unique systems approaches are particularly compelling.

Opportunities and challenges of big data for the social sciences: The case of genomic data.

PubMed

Liu, Hexuan; Guo, Guang

2016-09-01

In this paper, we draw attention to one unique and valuable source of big data, genomic data, by demonstrating the opportunities they provide to social scientists. We discuss different types of large-scale genomic data and recent advances in statistical methods and computational infrastructure used to address challenges in managing and analyzing such data. We highlight how these data and methods can be used to benefit social science research. Copyright © 2016 Elsevier Inc. All rights reserved.

A new hospital library: a marketing opportunity.

PubMed Central

Walker, M E

1995-01-01

A new or remodeled library presents a unique marketing opportunity for the hospital librarian. Furthermore, a well-designed library markets itself through its convenience, attractiveness, and ease of use. A marketing approach to library planning takes into account needs of users and of library staff and considers the librarian's relations with the architect as well as with hospital employees. This paper describes ways to combine library planning with marketing techniques and specifies aspects of the library that contribute to its good image. PMID:7581190

Institute for Sustainable Energy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Agrawal, Ajay

2016-03-28

Alternate fuels offer unique challenges and opportunities as energy source for power generation, vehicular transportation, and industrial applications. Institute for Sustainable Energy (ISE) at UA conducts innovative research to utilize the complex mix of domestically-produced alternate fuels to achieve low-emissions, high energy-efficiency, and fuel-flexibility. ISE also provides educational and advancement opportunities to students and researchers in the energy field. Basic research probing the physics and chemistry of alternative fuels has generated practical concepts investigated in a burner and engine test platforms.

75 FR 10815 - Notice of Proposed Withdrawal Extension and Opportunity for Public Meeting; Oregon

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-09

... ecological research values at the Abbott Creek Research Natural Area. The withdrawal created by PLO No. 6856... the protection of the unique natural and ecological research values at the Abbott Creek Research...

A Fragile Line

PubMed Central

Whiteley, Stuart

1972-01-01

The brutal murders carried out by Charles Manson and his 'family' seemed bizarre and abnormal in the extreme. But was Manson so uniquely evil or did his environment just happen to provide opportunities where a philosophy of violence could flourish unchecked? PMID:27671265

Agroecology for the Shrinking City

EPA Science Inventory

Many cities are experiencing long-term declines in population and economic activity. As a result, frameworks for urban sustainability need to address the unique challenges and opportunities of such shrinking cities. Shrinking, particularly in the U.S., has led to extensive vacant...

Feasibility study for a freeway corridor infrastructure health monitoring instrumentation testbed.

DOT National Transportation Integrated Search

2012-08-01

With current and near-term construction activities within the freeway system of Southeast Wisconsin, there is a unique : opportunity to develop a detailed understanding of their in-service performance by implementing a health monitoring : network tha...

Physiological and Anatomical Visual Analytics (PAVA) Background

EPA Pesticide Factsheets

The need to efficiently analyze human chemical disposition data from in vivo studies or in silico PBPK modeling efforts, and to see complex disposition data in a logical manner, has created a unique opportunity for visual analytics applid to PAD.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Head, Tim

The top quark is the heaviest fundamental particle. Its correspondingly short lifetime implies that it will decay before top flavoured hadrons can form. This provides an opportunity to study the properties of a quark without the effects of hadronisation, which is unique in the standard model.

The teaching of medical ethics.

PubMed Central

Sporken, P

1975-01-01

The following description of the situation in Maastricht in the Netherlands is unique as this is a new faculty of medicine and the opportunity has been taken to build the teaching of medical ethics into the curriculum from the start. PMID:1225974

State transportation policy initiative : a new strategic urban transportation planning process

DOT National Transportation Integrated Search

1995-06-01

Recent legislation and fiscal trends in Florida and nationwide have created a unique combination of constraints and opportunities, providing an impetus for examining the way Florida conducts transportation planning. In response to these challenges, t...

The Big Science Questions About Mercury's Ice-Bearing Polar Deposits After MESSENGER

NASA Astrophysics Data System (ADS)

Chabot, N. L.; Lawrence, D. J.

2018-05-01

Mercury’s polar deposits provide many well-characterized locations that are known to have large expanses of exposed water ice and/or other volatile materials — presenting unique opportunities to address fundamental science questions.

Build Your Own Payment Model.

PubMed

Berlin, Joey

2017-07-01

Physicians participating in MACRA have a unique opportunity to create and submit their own alternative payment models to the government and take command of their own future payments. At least one Texas physician is taking a crack at developing his own model.

Crescent Evaluation : appendix B : state case study evaluation report

DOT National Transportation Integrated Search

1994-02-01

The state case study evaluation approach uniquely captured an understanding of the potential of such a system by documenting the experiences, issues, and opportunities of selected key state government personnel from a cross-section of involved agenci...

Impacts of the Northridge Earthquake on transit and highway use

DOT National Transportation Integrated Search

1998-05-01

The Northridge earthquake provided a unique opportunity to examine travel behavior responses : to a major emergency. We examine travel patterns in two heavily damaged transportation corridors to determine how trip patterns changed over the recovery p...

Chocolate: a flavor and texture unlike any other.

PubMed

Morgan, J

1994-12-01

Cocoa butter is unique. The tree and flower from which it grows, the pod and its seed, as well as its postharvest handling are all different from those for any other food ingredient. Cocoa butter is the most critical raw material for chocolate, a foodstuff recognized long ago as having exceptional value. The triglyceride structure of cocoa butter gives cocoa butter unique solidification and liquefying properties, which give the chocolate manufacturer the opportunity to work with chocolate in ways that no other foods permit.

Unique mitochondrial DNA lineages in Irish stickleback populations: cryptic refugium or rapid recolonization?

PubMed

Ravinet, Mark; Harrod, Chris; Eizaguirre, Christophe; Prodöhl, Paulo A

2014-06-01

Repeated recolonization of freshwater environments following Pleistocene glaciations has played a major role in the evolution and adaptation of anadromous taxa. Located at the western fringe of Europe, Ireland and Britain were likely recolonized rapidly by anadromous fishes from the North Atlantic following the last glacial maximum (LGM). While the presence of unique mitochondrial haplotypes in Ireland suggests that a cryptic northern refugium may have played a role in recolonization, no explicit test of this hypothesis has been conducted. The three-spined stickleback is native and ubiquitous to aquatic ecosystems throughout Ireland, making it an excellent model species with which to examine the biogeographical history of anadromous fishes in the region. We used mitochondrial and microsatellite markers to examine the presence of divergent evolutionary lineages and to assess broad-scale patterns of geographical clustering among postglacially isolated populations. Our results confirm that Ireland is a region of secondary contact for divergent mitochondrial lineages and that endemic haplotypes occur in populations in Central and Southern Ireland. To test whether a putative Irish lineage arose from a cryptic Irish refugium, we used approximate Bayesian computation (ABC). However, we found no support for this hypothesis. Instead, the Irish lineage likely diverged from the European lineage as a result of postglacial isolation of freshwater populations by rising sea levels. These findings emphasize the need to rigorously test biogeographical hypothesis and contribute further evidence that postglacial processes may have shaped genetic diversity in temperate fauna.

Unique mitochondrial DNA lineages in Irish stickleback populations: cryptic refugium or rapid recolonization?

PubMed Central

Ravinet, Mark; Harrod, Chris; Eizaguirre, Christophe; Prodöhl, Paulo A

2014-01-01

Repeated recolonization of freshwater environments following Pleistocene glaciations has played a major role in the evolution and adaptation of anadromous taxa. Located at the western fringe of Europe, Ireland and Britain were likely recolonized rapidly by anadromous fishes from the North Atlantic following the last glacial maximum (LGM). While the presence of unique mitochondrial haplotypes in Ireland suggests that a cryptic northern refugium may have played a role in recolonization, no explicit test of this hypothesis has been conducted. The three-spined stickleback is native and ubiquitous to aquatic ecosystems throughout Ireland, making it an excellent model species with which to examine the biogeographical history of anadromous fishes in the region. We used mitochondrial and microsatellite markers to examine the presence of divergent evolutionary lineages and to assess broad-scale patterns of geographical clustering among postglacially isolated populations. Our results confirm that Ireland is a region of secondary contact for divergent mitochondrial lineages and that endemic haplotypes occur in populations in Central and Southern Ireland. To test whether a putative Irish lineage arose from a cryptic Irish refugium, we used approximate Bayesian computation (ABC). However, we found no support for this hypothesis. Instead, the Irish lineage likely diverged from the European lineage as a result of postglacial isolation of freshwater populations by rising sea levels. These findings emphasize the need to rigorously test biogeographical hypothesis and contribute further evidence that postglacial processes may have shaped genetic diversity in temperate fauna. PMID:25360281

Mission options for rendezvous with the most accessible Near-Earth Asteroid - 1989 ML

NASA Technical Reports Server (NTRS)

Mcadams, Jim V.

1992-01-01

The recent discovery of the Amor-class 1989 ML, the most accessible known asteroid for minimum-energy rendezvous missions, has expedited the search for frequent, low-cost Near-Earth Asteroid rendezvous and round-trip missions. This paper identifies trajectory characteristics and assesses mass performance for low Delta V ballistic rendezvous opportunities to 1989 ML during the period 1996-2010. This asteroid also offers occasional unique extended mission opportunities, such as the lowest known Delta V requirement for any asteroid sample return mission as well as pre-rendezvous asteroid flyby and post-rendezvous comet flyby opportunities requiring less than 5.25 km/sec total Delta V. This paper also briefly comments concerning mission opportunities for asteroid 1991 JW, which recently replaced other known asteroids as the most accessible Near-Earth Asteroid for fast rendezvous and round-trip missions.

ISO 50001 for US Commercial Buildings - Current Status and Opportunities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Jingjing; Sheaffer, Paul

''ISO 50001: 2011 Energy management systems – Requirements with guidance for use'' is a voluntary International Standard which provides organizations a proven framework to manage energy and continuously improve their energy performance. Implementing ISO 50001 in the commercial building sector has its unique opportunities and challenges in comparison with the industrial sector. The energy footprint of a portfolio of commercial buildings can be just as significant as a large industrial facility in comparison. There are many energy-saving opportunities in commercial buildings that can be addressed without capital investments, and the perceived risks for making energy improvements can be lower thanmore » in the industrial sector. In addition, the energy-consuming systems in commercial buildings are limited in types and have many similarities across buildings, which makes it much easier to standardize many ISO 50001 required processes, 5 procedures and documents to simplify implementation. There are also some sector-unique challenges, such as less familiar with ISO systems and the certification process. Another challenge arises from the complexity in some buildings’ ownership, tenancy, and O&M responsibilities. This whitepaper discusses these opportunities and issues in detail. The paper also recommends the characteristics of organizations in the commercial building sector that can benefit the most from adopting the ISO 50001 standard – namely the “suitable market”. Eight segments (education, food sales, retail, inpatient health care, hospitality, office buildings, laboratories and data centers) within the commercial building sector are highlighted.« less

So, Here's the Story

ERIC Educational Resources Information Center

Columba, Lynn

2013-01-01

Mathematics is about reasoning, patterns, and making sense of things. Children's literature provides a powerful opportunity to foster unique experiences in mathematics learning. Storybooks, thinking strategies, and manipulatives offer a winning combination for mastering multiplication facts based on conceptual ideas and relationships. The most…

Talking points for the Olympic Games' transportation plan for the 1996 Summer Olympics in Atlanta

DOT National Transportation Integrated Search

1995-04-27

The Olympic Games in Atlanta present a unique and timely : opportunity for the United States to showcase traveler : information services and technologies associated with Intelligent : Transportation Systems (ITS), with the goals of stimulating : furt...

USE OF CITIZEN BIRD POPULATION MONITORING DATA FOR ECOLOGICAL RISK ASSESSMENT

EPA Science Inventory

Birds are among the most conspicuous and easily monitored indicators of environmental health and change. Although volunteer avian monitoring ('citizen science') programs provide unique opportunities to gather data at fine and broad geographic scales simultaneously, and over long...

Opportunities and questions for the fundamental biological sciences in space

NASA Technical Reports Server (NTRS)

Sharp, Joseph C.; Vernikos, Joan

1993-01-01

With the advent of sophisticated space facilities we discuss the overall nature of some biological questions that can be addressed. We point out the need for broad participation by the biological community, the necessary facilities, and some unique requirements.

Master of Public Health | Cancer Prevention Fellowship Program

Cancer.gov

One of the unique features of the CPFP is the opportunity to receive formal, academic training in public health. By pursuing an MPH or equivalent degree, fellows learn about the current role and historical context of cancer prevention in public health.

Evolution of a tissue-specific splicing network

PubMed Central

Taliaferro, J. Matthew; Alvarez, Nehemiah; Green, Richard E.; Blanchette, Marco; Rio, Donald C.

2011-01-01

Alternative splicing of precursor mRNA (pre-mRNA) is a strategy employed by most eukaryotes to increase transcript and proteomic diversity. Many metazoan splicing factors are members of multigene families, with each member having different functions. How these highly related proteins evolve unique properties has been unclear. Here we characterize the evolution and function of a new Drosophila splicing factor, termed LS2 (Large Subunit 2), that arose from a gene duplication event of dU2AF50, the large subunit of the highly conserved heterodimeric general splicing factor U2AF (U2-associated factor). The quickly evolving LS2 gene has diverged from the splicing-promoting, ubiquitously expressed dU2AF50 such that it binds a markedly different RNA sequence, acts as a splicing repressor, and is preferentially expressed in testes. Target transcripts of LS2 are also enriched for performing testes-related functions. We therefore propose a path for the evolution of a new splicing factor in Drosophila that regulates specific pre-mRNAs and contributes to transcript diversity in a tissue-specific manner. PMID:21406555

On the origin of sex as vaccination.

PubMed

Sterrer, Wolfgang

2002-06-21

In the theory of the origin of sex as vaccination, I propose that the eukaryote genome accreted from prokaryan symbiont genomes in numerous rounds of lateral gene transfer during which sex diverged from unilateral parasitic infection, as an increasingly ritualized, reciprocal vaccination against superinfection. Sex-as-syngamy (fusion sex) arose when infected proto-eukaryan hosts began swapping nuclearized genomes containing coevolved, vertically transmitted ("attenuated") symbionts that conveyed protection against horizontal superinfection by more virulent symbionts. Sex-as-meiosis (fission sex) evolved as a host strategy to uncouple (and thereby emasculate) the acquired symbiont genomes. The chimeric nature, distribution over discrete chromosomes, and mosaic composition of the eukaryan nuclear genome derive from multiple rounds of acquiring and uncoupling prokaryan genomes. Genome compatibility-based recognition of self and mates came to define sex, mate choice, and the biological species. By generating unique individuality, sex now persists as an elaborate (hence tamper-proof) periodic device for an organism to thwart both endo- and exogenous challengers, and stay ahead of an environment whose capriciousness may largely result from the success of its own forebears.

Cold-adapted digestive aspartic protease of the clawed lobsters Homarus americanus and Homarus gammarus: biochemical characterization.

PubMed

Rojo, Liliana; García-Carreño, Fernando; de Los Angeles Navarrete del Toro, Maria

2013-02-01

Aspartic proteinases in the gastric fluid of clawed lobsters Homarus americanus and Homarus gammarus were isolated to homogeneity by single-step pepstatin-A affinity chromatography; such enzymes have been previously identified as cathepsin D-like enzymes based on their deduced amino acid sequence. Here, we describe their biochemical characteristics; the properties of the lobster enzymes were compared with those of its homolog, bovine cathepsin D, and found to be unique in a number of ways. The lobster enzymes demonstrated hydrolytic activity against synthetic and natural substrates at a wider range of pH; they were more temperature-sensitive, showed no changes in the K(M) value at 4°C, 10°C, and 25°C, and had 20-fold higher k(cat)/K(M) values than bovine enzyme. The bovine enzyme was temperature-dependent. We propose that both properties arose from an increase in molecular flexibility required to compensate for the reduction of reaction rates at low habitat temperatures. This is supported by the fast denaturation rates induced by temperature.

Enhancing metaproteomics-The value of models and defined environmental microbial systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Herbst, Florian-Alexander; Lünsmann, Vanessa; Kjeldal, Henrik

2016-01-21

Metaproteomics - the large-scale characterization of the entire protein complement of environmental microbiota at a given point in time - added unique features and possibilities to study environmental microbial communities and to unravel these “black boxes”. New technical challenges arose which were not an issue for classical proteome analytics before and choosing the appropriate model system applicable to the research question can be difficult. Here, we reviewed different model systems for metaproteome analysis. Following a short introduction to microbial communities and systems, we discussed the most used systems ranging from technical systems over rhizospheric models to systems for the medicalmore » field. This includes acid mine drainage, anaerobic digesters, activated sludge, planted fixed bed reactors, gastrointestinal simulators and in vivo models. Model systems are useful to evaluate the challenges encountered within (but not limited to) metaproteomics, including species complexity and coverage, biomass availability or reliable protein extraction. The implementation of model systems can be considered as a step forward to better understand microbial responses and ecological distribution of member organisms. In the future, novel improvements are necessary to fully engage complex environmental systems.« less

Gelastic seizures with dancing arising from the anterior prefrontal cortex.

PubMed

Neilson, John; Snyder, Tom; Pugh, Jeff; Wheatley, Matt; Tang-Wai, Richard

2014-06-01

This case report provides insight into the function of the anterior prefrontal cortex (aPFC), specifically Brodmann Area 10 (BA10), and its interconnectivity. We present a 10-year-old patient with lesional epilepsy and ictal onset, localised to BA10 in the aPFC. Thirty-four seizures were recorded. All seizures involved a demonstration of elation with laughter that was associated with a variety of different patterns of complex motor behaviour that included performing specific celebratory movements and acting out a Michael Jackson dance move. Electrographically, the seizures were all stereotyped and arose from the right frontal region, followed by a distinct left temporal ictal rhythm that corresponded with the onset of the behaviours. The lesion in the right aPFC was identified as a mixed lesion with both dysembryoplastic neuroepithelial tumour cells and type II cortical dysplasia. The electrographic analysis and unique seizure semiology suggest a connection between the aPFC and the contralateral temporal lobe. This neural pathway appears to be involved in the activation of previously formed procedural memories, creating an intensely positive emotional experience.

Direct observation of episodic growth in an abyssal xenophyophore (Protista)

NASA Astrophysics Data System (ADS)

Gooday, A. J.; Bett, B. J.; Pratt, D. N.

1993-11-01

Three specimens of the xenophyophore Reticulammina labyrinthica were photographed on the Madeira Abyssal Plain (31°6.1'N, 21°10.9'W; 4944 m) using the Bathysnap time-lapse camera system. During the 8 month observation period, the specimens underwent an estimated 3-10 fold increase in volume. Growth occurred episodically in several distinct phases, each lasting 2-3 days, during which sediment was collected and incorporated into the test. These phases were separated by fairly regular periods of about 2 months when the organisms showed little obvious activity. The growth phases were approximately synchronous between specimens. However, it is not clear whether the periodicity and apparent synchronization of these events resulted from an external (environmental) cue or whether growth is internally controlled and the synchronization arose by chance. These unique observations, which represent the first direct measurement of growth in any abyssal organism living outside a hydrothermal vent field, suggest that xenophyophores combine test growth with deposit feeding. The tests appear to grow more quickly, and to be more active, dynamic structures, than previously believed.

Molecular phylogenetic position of hexactinellid sponges in relation to the Protista and Demospongiae.

PubMed

West, L; Powers, D

1993-01-01

Although it is generally accepted that the first multicellular organisms arose from unicellular ancestors, the phylogenetic relationships linking these groups remain unclear. Anatomical, physiological, and molecular studies of current multicellular organisms with relatively simple body organization suggest key characteristics of the earliest multicellular lineages. Glass sponges, the Hexactinellida, possess cellular characteristics that resemble some unicellular protistan organisms. These unique sponges were abundant in shallow seas of the early Cambrian, but they are currently restricted to polar habitats or very deep regions of the world oceans. Due in part to their relative inaccessibility, their potential significance to the early phylogeny of the eukaryotic kingdoms has been largely overlooked. We used sequences of the 18s ribosomal RNA gene of Farrea occa, a representative of the deep-water hexactinellid sponges, and Coelocarteria singaporense, a representative of the more common demosponges, and compared them with selected ribosomal RNA gene sequences available within the Protista. Using four computational methods for phylogenetic analysis of ribosomal DNA sequences, we found that the hexactinellid sponge-demosponge cluster is most closely related to Volvox and Acanthamoeba.

Geologic Mapping of the Meridiani Region, Mars

NASA Technical Reports Server (NTRS)

Hynek, B. M.

2008-01-01

The light toned bedrock that has been observed at the Mars Exploration Rover Opportunity landing site is an upper layer in a sequence >600 m thick in places. These outcrops contain mineral and textural signatures that require interaction of, and possibly formation from, water. Many distinct layers are visible in the remote sensing data (e.g. Figure 1) and no work has ever characterized the full set of these materials that cover an area >3 105 km2 spanning 20 of longitude. Thus, whatever water-related process( es?) altered, and possibly formed, the rocks at the Opportunity landing site extended over a vast region of Mars. Yet many questions remain to be answered, such as: (1) in what capacity did water form and alter the deposits?, (2) what are the temporal and spatial relations with other major events known from ancient Mars?, and (3) would this type of environment have been conducive to the development of life? To address these questions we are completing a detailed geologic, stratigraphic, and thermophysical properties study of this widespread terrain. Specifically, we are drafting a 1:2M-scale geological map covering the full extent of these water-related deposits. In tandem with the mapping, Hynek and Phillips [1] have conducted a preliminary stratigraphic analysis of the stack of materials. After mapping is complete, we will study the thermophysical properties of the varied layers to derive possible compositional information of the materials. These tasks serve several purposes including gaining an understanding of the complex nature of these materials, their potential source region(s), and their timing of emplacement. All of these efforts are necessary to place the observations by the Opportunity Rover in a broader context and prepare for potential future landed missions to the region. Understanding the large-scale paleohydrology of Mars is central to NASA s goals and vital for determining if life ever arose on the planet.

Mosaic evolution of the mammalian auditory periphery.

PubMed

Manley, Geoffrey A

2013-01-01

The classical mammalian auditory periphery, i.e., the type of middle ear and coiled cochlea seen in modern therian mammals, did not arise as one unit and did not arise in all mammals. It is also not the only kind of auditory periphery seen in modern mammals. This short review discusses the fact that the constituents of modern mammalian auditory peripheries arose at different times over an extremely long period of evolution (230 million years; Ma). It also attempts to answer questions as to the selective pressures that led to three-ossicle middle ears and the coiled cochlea. Mammalian middle ears arose de novo, without an intermediate, single-ossicle stage. This event was the result of changes in eating habits of ancestral animals, habits that were unrelated to hearing. The coiled cochlea arose only after 60 Ma of mammalian evolution, driven at least partly by a change in cochlear bone structure that improved impedance matching with the middle ear of that time. This change only occurred in the ancestors of therian mammals and not in other mammalian lineages. There is no single constellation of structural features of the auditory periphery that characterizes all mammals and not even all modern mammals.

Racial dialogues: challenges faculty of color face in the classroom.

PubMed

Sue, Derald Wing; Rivera, David P; Watkins, Nicole L; Kim, Rachel H; Kim, Suah; Williams, Chantea D

2011-07-01

Research on the experiences of faculty of color in predominantly White institutions (PWIs) suggests that they often experience the campus climate as invalidating, alienating, and hostile. Few studies, however, have actually focused on the classroom experiences of faculty of color when difficult racial dialogues occur. Using Consensually Qualitative Research, eight faculty of color were interviewed about their experiences in the classroom when racially tinged topics arose. Three major findings emerged. First, difficult racial dialogues were frequently instigated by the presence of racial microaggressions delivered toward students of color or the professor. Dialogues on race were made more difficult when the classrooms were diverse, when heated emotions arose, when there was a strong fear of self-disclosure, and when racial perspectives differed. Second, all faculty experienced an internal struggle between balancing their own values and beliefs with an attempt to remain objective. This conflict was often described as exhausting and energy-depleting. Third, faculty of color described both successful and unsuccessful strategies in facilitating difficult dialogues on race that arose in the course of their teaching. These findings have major implications for how PWIs can develop new programs, policies, and practices that will aid and support colleagues of color.

OSTEOSARCOMA IN AFRICAN HEDGEHOGS (ATELERIX ALBIVENTRIS): FIVE CASES.

PubMed

Reyes-Matute, Alonso; Méndez-Bernal, Adriana; Ramos-Garduño, Liliana-Aurora

2017-06-01

Osteosarcomas are unusual neoplasms in African hedgehogs ( Atelerix albiventris ) and have been reported in extraskeletal and skeletal locations, including mandible, ribs, and vertebra. Five hedgehogs with osteosarcoma submitted to the Pathology Department at Facultad de Medicina Veterinaria y Zootecnia, National Autonomous University of Mexico are reported. In two cases, the neoplasm arose from the skull; one case arose from the ribs with associated compression of the thoracic and abdominal cavity, and another case involved the vertebrae. In the last case, the neoplasm arose from the scapula. Histologic lesions were similar in all cases and consisted of well-demarcated nodules in which neoplastic cells were arranged in sheets of polyhedral to spindle-shaped cells with interspersed areas of necrosis. Numerous trabeculae of osteoid were present throughout the tumors. No metastases were detected. The predominant histologic pattern was osteoblastic, but a telangiectatic-like pattern was observed in the vertebral osteosarcoma. Electron microscopy was performed in two cases, and malignant osteoblasts had features consistent with descriptions in other species, including deposits of hydroxyapatite in osteoid. According to these cases and previously published data, axial osteosarcomas are more frequent in contrast to appendicular osteosarcomas in African hedgehogs, and metastases are rare.

COMPREHENSIVE PLAN FOR A SUSTAINABLE URBAN WATERSHED

EPA Science Inventory

Technical Challenge. This proposal deals with the urban watershed. The urban watershed is important to the quality of life in the city. For many urban dwellers, the urban stream represents a unique opportunity for recreation and the experience of the ...

78 FR 14620 - Joint Development: Proposed Circular

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-06

... of opportunities for private sector participation in public transportation projects, and includes the most current guidance for the federal public transportation program. By this notice, FTA invites public... that are not unique to public transportation projects, but which have application to all federally...

Distributing Congestion Management System Information Using the World Wide Web

DOT National Transportation Integrated Search

1997-01-01

The Internet is a unique medium for the distribution of information, and it provides a tremendous opportunity to take advantage of peoples innate interest in transportation issues as they relate to their own lives. In particular, the World Wide Web (...

Adaptive Management of Urban Ecosystem Restoration: Learning From Restoration Managers in Rhode Island, USA

EPA Science Inventory

Urban aquatic restoration can be difficult to accomplish because of complications like industrial pollutants, population density, infrastructure, and expense; however, unique opportunities in urban settings, including the potential to provide benefits to many diverse people, can ...

Energy and Greenhouse Gas Emission Reduction Opportunities for Civil Works Projects Unique to the US Army Corps of Engineers

DTIC Science & Technology

2012-10-26

3600 hp diesel engine .................................................................................. 24 20 Diesel engine turbocharger ...ERDC/CERL TR-12-19 24 Figure 19. Fairbanks Morse 3600 hp diesel engine. Figure 20. Diesel engine turbocharger . Table 7. Energy consuming

44 CFR 360.1 - Purpose.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Purpose. The Emergency Management Training Program is designed to enhance the States' emergency management... give States the opportunity to develop new capabilities and techniques. The Program is an ongoing intergovernmental endeavor which combines financial and human resources to fill the unique training needs of local...

44 CFR 360.1 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Purpose. The Emergency Management Training Program is designed to enhance the States' emergency management... give States the opportunity to develop new capabilities and techniques. The Program is an ongoing intergovernmental endeavor which combines financial and human resources to fill the unique training needs of local...

When Worlds Collide: Witnessing Planetary-Scale Impacts in the Coming Decades

NASA Astrophysics Data System (ADS)

Masiero, J. R.; Bauer, J. M.; Grav, T.; Mainzer, A. K.

2017-02-01

Asteroid impacts offer a unique opportunity to study the collisional processes that shape planetary systems. In the coming decades, expanded surveys may give us the chance to predict an impact with enough advance warning to observe it in situ.

High resolution stable isotope and carbonate variability during the early Oligocene climate transition: Walvis Ridge (ODP Site 1263)

USGS Publications Warehouse

2007-01-01

resolution reconstruction of the Eocene/Oligocene from the Atlantic basin to date, and provide us with a unique opportunity to investigate the fine-scale interplay of glaciation and the global carbon cycle.

Hazardous Waste Resources for Tribal Nations in the Midwest

EPA Pesticide Factsheets

Hazardous waste on tribal lands presents a unique set of opportunities and obstacles. This website is intended to be a host for resources that can help Tribal Nations understand the dynamics of hazardous waste and provide guidance on building tribal hazard

Reading, Dyslexia and the Brain

ERIC Educational Resources Information Center

Goswami, Usha

2008-01-01

Background: Neuroimaging offers unique opportunities for understanding the acquisition of reading by children and for unravelling the mystery of developmental dyslexia. Here, I provide a selective overview of recent neuroimaging studies, drawing out implications for education and the teaching of reading. Purpose: The different neuroimaging…

Bilingual School Psychology: Challenges and Opportunities

ERIC Educational Resources Information Center

Olvera, Pedro; Olvera, Veronica I.

2015-01-01

National demographics clearly demonstrate that children from culturally and linguistically diverse (CLD) backgrounds are on the rise. Many regions in the United States are experiencing unprecedented growth in English language learner (ELL) populations without adequately trained personnel to serve this unique population. Unfortunately, the…

75 FR 8099 - Public Workshop on Marine Technology and Standards

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-23

... Technology and Standards AGENCY: Coast Guard, DHS. ACTION: Notice. SUMMARY: The American Society of...-day public workshop in Washington DC on marine technology and standards. This public workshop will provide a unique opportunity for classification societies, industry groups, standards development...

Partners in Collaboration: The Homan Square Project.

ERIC Educational Resources Information Center

Hollinger-Smith, Linda

1998-01-01

Collaboration between a community coalition and a nursing school in Chicago resulted in a primary health care clinic, school-based health centers, family education and counseling programs, and screening services. It provides a unique opportunity to combine service delivery and academic education. (SK)

Michael F. Vaccaro Honors Attorney Fellowship Program in our Philadelphia (Region 3) Office

EPA Pesticide Factsheets

The Michael F. Vaccaro Honors Attorney Fellowship provides a unique opportunity to practice law in a major governmental environmental organization, and to receive extensive training in and exposure to environmental law and policy work in the public sector.

Long-Term Studies of Prescribed Burning in Loblolly Pine Forests of the Southeastern Coastal Plain

Treesearch

Thomas A. Waldrop; David H. van Lear; F. Thomas Lloyd; William R. Harms

1987-01-01

Prescribed fire provides many benefits in southern pine A study begun in 1946 provides a unique opportunity stands. to observe long-term changes in understory vegetation, soil properties, and overstory tree growth caused by repeated burning.

Feelings of Women With Strong Family Histories Who Subsequent to Their Breast Cancer Diagnosis Tested BRCA Positive.

PubMed

Joseph, Meera; Rab, Faiza; Panabaker, Karen; Nisker, Jeff

2015-05-01

Family physicians in Canada as reported in several studies do not recognize the importance of family history in relation to breast/ovarian cancer and thus Canadian women with strong family histories continue to develop early-onset breast cancer without the knowledge of or ability to make choices regarding increased surveillance or preventative strategies. This study explored the feelings of women who learned about their hereditary risk only after their diagnosis younger than 52 years and who eventually tested positive for a BRCA gene mutation. Thirty-four such women were mailed an invitation to participate in this research including a letter of information, consent form, and discussion prompts for their written narrative response. Rigorous mixed method analyses were performed using Charmaz-based qualitative analyses as well as quantitative analyses. Thirteen women (38.2%) responded with narratives for qualitative analysis from which 4 themes were coconstructed as follows: I, types of emotions; II, emotional response; III, coping with emotions; and IV, advice to women at similar risk. Women felt they should have learned about their hereditary risk from their family physician and through public education before their diagnosis. Although not experienced at the time of diagnosis, anger, frustration, and regret were experienced after receiving their BRCA results. These emotions arose from our research participants' lack of opportunity for prior genetic counseling and testing opportunity for genetic counseling and testing. With increased public and physician education, it is hoped that women with significant family histories of breast/ovarian cancer will be identified before diagnosis and given options regarding cancer surveillance and risk reduction strategies.

Implementation of a Post-Code Pause: Extending Post-Event Debriefing to Include Silence.

PubMed

Copeland, Darcy; Liska, Heather

2016-01-01

This project arose out of a need to address two issues at our hospital: we lacked a formal debriefing process for code/trauma events and the emergency department wanted to address the psychological and spiritual needs of code/trauma responders. We developed a debriefing process for code/trauma events that intentionally included mechanisms to facilitate recognition, acknowledgment, and, when needed, responses to the psychological and spiritual needs of responders. A post-code pause process was implemented in the emergency department with the aims of standardizing a debriefing process, encouraging a supportive team-based culture, improving transition back to "normal" activities after responding to code/trauma events, and providing responders an opportunity to express reverence for patients involved in code/trauma events. The post-code pause process incorporates a moment of silence and the addition of two simple questions to a traditional operational debrief. Implementation of post-code pauses was feasible despite the fast paced nature of the department. At the end of the 1-year pilot period, staff members reported increases in feeling supported by peers and leaders, their ability to pay homage to patients, and having time to regroup prior to returning to their assignment. There was a decrease in the number of respondents reporting having thoughts or feelings associated with the event within 24 hr. The pauses create a mechanism for operational team debriefing, provide an opportunity for staff members to honor their work and their patients, and support an environment in which the psychological and spiritual effects of responding to code/trauma events can be acknowledged.

'Nobody is after you; it is your initiative to start work': a qualitative study of health workforce absenteeism in rural Uganda.

PubMed

Tweheyo, Raymond; Daker-White, Gavin; Reed, Catherine; Davies, Linda; Kiwanuka, Suzanne; Campbell, Stephen

2017-01-01

Published evidence on the drivers of absenteeism among the health workforce is mainly limited to high-income countries. Uganda suffers the highest rate of health workforce absenteeism in Africa, attracting attention but lacking a definitive ameliorative strategy. This study aimed to explore the underlying reasons for absenteeism in the public and private 'not-for-profit' health sector in rural Uganda. We undertook an empirical qualitative study, located within the critical realist paradigm. We used case study methodology as a sampling strategy, and principles of grounded theory for data collection and analysis. Ninety-five healthcare workers were recruited through focus groups and in-depth interviews. The NVivo V.10 software package was used for data management. Healthcare workers' absenteeism was explained by complex interrelated influences that could be seen to be both external to, and within, an individual's motivation. External influences dominated in the public sector, especially health system factors, such as delayed or omitted salaries, weak workforce leadership and low financial allocation for workers' accommodation. On the other hand, low staffing-particularly in the private sector-created work overload and stress. Also, socially constructed influences existed, such as the gendered nature of child and elderly care responsibilities, social class expectations and reported feigned sickness. Individually motivated absenteeism arose from perceptions of an inadequate salary, entitlement to absence, financial pressures heightening a desire to seek supplemental income, and educational opportunities, often without study leave. Health workforce managers and policy makers need to improve governance efficiencies and to seek learning opportunities across different health providers.

Opportunities for research in space life sciences aboard commercial suborbital flights.

PubMed

Wagner, Erika B; Charles, John B; Cuttino, Charles Marsh

2009-11-01

The emergence of commercial suborbital spaceflight offers a wide range of new research and development opportunities for those in the space life sciences. Large numbers of diverse flyers, frequent re-flights, and flexible operations provide a fertile ground for both basic and applied science, as well as technology demonstrations. This commentary explores some of the unique features available to the space life science community and encourages engagement with commercial developers and operators during the design phase to help optimize platform designs and operations for future research.

NASA's Space Launch System: An Evolving Capability for Exploration

NASA Technical Reports Server (NTRS)

Robinson, Kimberly F.; Hefner, Keith; Hitt, David

2015-01-01

Designed to enable human space exploration missions, including eventually landings on Mars, NASA's Space Launch System (SLS) represents a unique launch capability with a wide range of utilization opportunities, from delivering habitation systems into the lunar vicinity to high-energy transits through the outer solar system. The vehicle will be able to deliver greater mass to orbit than any contemporary launch vehicle. SLS will also be able to carry larger payload fairings than any contemporary launch vehicle, and will offer opportunities for co-manifested and secondary payloads.

'Bounce' and Shergotty Share Common Ground

NASA Technical Reports Server (NTRS)

2004-01-01

This illustration compares the spectrum of 'Bounce,' a rock at Meridiani Planum, to that of a martian meteorite found on Earth called Shergotty. Bounce's spectrum, and thus mineral composition, is unique to the rocks studied so far at Merdiani Planum and Gusev Crater, the landings sites of the Mars Exploration Rovers Opportunity and Spirit. However, the results here indicate that Bounce is not a one-of-a-kind rock, but shares origins with Shergotty. Shergotty landed in India in 1865. Bounce's spectra were taken on sol 67 by Opportunity's Moessbauer spectrometer.

Current status of endovascular catheter robotics.

PubMed

Lumsden, Alan B; Bismuth, Jean

2018-06-01

In this review, we will detail the evolution of endovascular therapy as the basis for the development of catheter-based robotics. In parallel, we will outline the evolution of robotics in the surgical space and how the convergence of technology and the entrepreneurs who push this evolution have led to the development of endovascular robots. The current state-of-the-art and future directions and potential are summarized for the reader. Information in this review has been drawn primarily from our personal clinical and preclinical experience in use of catheter robotics, coupled with some ground-breaking work reported from a few other major centers who have embraced the technology's capabilities and opportunities. Several case studies demonstrating the unique capabilities of a precisely controlled catheter are presented. Most of the preclinical work was performed in the advanced imaging and navigation laboratory. In this unique facility, the interface of advanced imaging techniques and robotic guidance is being explored. Although this procedure employs a very high-tech approach to navigation inside the endovascular space, we have conveyed the kind of opportunities that this technology affords to integrate 3D imaging and 3D control. Further, we present the opportunity of semi-autonomous motion of these devices to a target. For the interventionist, enhanced precision can be achieved in a nearly radiation-free environment.

Advancing stroke genomic research in the age of Trans-Omics big data science: Emerging priorities and opportunities.

PubMed

Owolabi, Mayowa; Peprah, Emmanuel; Xu, Huichun; Akinyemi, Rufus; Tiwari, Hemant K; Irvin, Marguerite R; Wahab, Kolawole Wasiu; Arnett, Donna K; Ovbiagele, Bruce

2017-11-15

We systematically reviewed the genetic variants associated with stroke in genome-wide association studies (GWAS) and examined the emerging priorities and opportunities for rapidly advancing stroke research in the era of Trans-Omics science. Using the PRISMA guideline, we searched PubMed and NHGRI- EBI GWAS catalog for stroke studies from 2007 till May 2017. We included 31 studies. The major challenge is that the few validated variants could not account for the full genetic risk of stroke and have not been translated for clinical use. None of the studies included continental Africans. Genomic study of stroke among Africans presents a unique opportunity for the discovery, validation, functional annotation, Trans-Omics study and translation of genomic determinants of stroke with implications for global populations. This is because all humans originated from Africa, a continent with a unique genomic architecture and a distinctive epidemiology of stroke; as well as substantially higher heritability and resolution of fine mapping of stroke genes. Understanding the genomic determinants of stroke and the corresponding molecular mechanisms will revolutionize the development of a new set of precise biomarkers for stroke prediction, diagnosis and prognostic estimates as well as personalized interventions for reducing the global burden of stroke. Copyright © 2017 Elsevier B.V. All rights reserved.

Traditional Medicines and Kidney Disease in Low- and Middle-Income Countries: Opportunities and Challenges.

PubMed

Stanifer, John W; Kilonzo, Kajiru; Wang, Daphne; Su, Guobin; Mao, Wei; Zhang, Lei; Zhang, La; Nayak-Rao, Shobhana; Miranda, J Jaime

2017-05-01

Traditional medicines are a principal form of health care for many populations, particularly in low- and middle-income countries, and they have gained attention as an important means of health care coverage globally. In the context of kidney diseases, the challenges and opportunities presented by traditional medicine practices are among the most important considerations for developing effective and sustainable public health strategies. However, little is known about the practices of traditional medicines in relation to kidney diseases, especially concerning benefits and harms. Kidney diseases may be caused, treated, prevented, improved, or worsened by traditional medicines depending on the setting, the person, and the types, modes, and frequencies of traditional medicine use. Given the profound knowledge gaps, nephrology practitioners and researchers may be uniquely positioned to facilitate more optimal public health strategies through recognition and careful investigation of traditional medicine practices. Effective implementation of such strategies also will require local partnerships, including engaging practitioners and users of traditional medicines. As such, practitioners and researchers investigating kidney diseases may be uniquely positioned to bridge the cultural, social, historical, and biologic differences between biomedicine and traditional medicine, and they have opportunities to lead efforts in developing public health strategies that are sensitive to these differences. Copyright © 2017 Elsevier Inc. All rights reserved.

ACTS of Education

NASA Technical Reports Server (NTRS)

Bauer, Robert; Krawczyk, Richard; Gargione, Frank; Kruse, Hans; Vrotsos, Pete (Technical Monitor)

2002-01-01

Now in its ninth year of operations, the Advanced Communications Technology Satellite (ACTS) program has continued, although since May 2000 in a new operations arrangement involving a university based consortium, the Ohio Consortium for Advanced Communications Technology (OCACT), While NASA has concluded its experimental intentions of ACTS, the spacecraft's ongoing viability has permitted its further operations to provide educational opportunities to engineering and communications students interested in satellite operations, as well as a Ka-band test bed for commercial interests in utilizing Kaband space communications. The consortium has reached its first year of operations. This generous opportunity by NASA has already resulted in unique educational opportunities for students in obtaining "hands-on" experience, such as, in satellite attitude control. An update is presented on the spacecraft and consortium operations.

A case for the protection of saline and hypersaline environments: a microbiological perspective.

PubMed

Paul, Varun G; Mormile, Melanie R

2017-08-01

Saline and hypersaline environments are known for their unique geochemical properties, microbial populations and aesthetic appeal. Microbial activities and a spectrum of diversity seen in hypersaline environments are distinct with many novel species being identified and reported on a regular basis. Many distinguishing characteristics about the adaptation, morphology, evolutionary history, and potential environmental and biotechnological applications of these organisms are continually investigated. An abundance of interdisciplinary activities and opportunities exist to explore and understand the importance of these environments that potentially hold promising solutions for current and future global issues. Therefore, it is critical to conserve these unique environments and limit the damage inflicted by anthropogenic influences. Increased salinization due to water diversions, undesired freshening, extensive mineral extraction, sewage effluents, pollution due to agricultural runoff and industrial processes, urbanization, and global climate change are factors negatively affecting hypersaline lakes and their surrounding environments. If these harmful effects continue to proceed at the current or even accelerated rates, irrevocable consequences for these environments will occur, resulting in the loss of potential opportunities to gain new knowledge of the biogeochemistry as well as beneficial microbial populations closely associated with these unique and interesting environments. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Bilateral tuberculous otitis media: An unique presentation.

PubMed

Bhatkar, Dhiraj; Utpat, Ketaki; Desai, Unnati; Joshi, Jyotsna M

2017-10-01

Tuberculous otitis media (TOM) is an uncustomary variety of tuberculosis (TB) usually seen secondary to pulmonary tuberculosis or associated with it. It is characterized by indolent and heterogeneous presentations. Diagnosis warrants clinical, radiological, and microbiological amalgamation. It is hence challenging and frequently delayed leading to disabling complications. Opportunate suspicion, timely diagnosis and appropriate antituberculosis therapy are the key to successful management. We report a unique case of bilateral TOM occurring in an immunocompetent adult. Copyright © 2016 Tuberculosis Association of India. Published by Elsevier B.V. All rights reserved.

Transgender populations and HIV: unique risks, challenges and opportunities.

PubMed

Wansom, Tanyaporn; Guadamuz, Thomas E; Vasan, Sandhya

2016-04-01

Due to unique social, behavioural, structural and biological issues, transgender (TG) populations, especially TG women, are at high risk for HIV acquisition. This increased risk is multifactorial, due to differing psychosocial risk factors, poorer access to TG-specific healthcare, a higher likelihood of using exogenous hormones or fillers without direct medical supervision, interactions between hormonal therapy and antiretroviral therapy, and direct effects of hormonal therapy on HIV acquisition and immune control. Further research is needed to elucidate these mechanisms of risk and to help design interventions to reduce HIV risk among transgender populations.

Bringing nanomedicines to market: regulatory challenges, opportunities, and uncertainties.

PubMed

Nijhara, Ruchika; Balakrishnan, Krishna

2006-06-01

Scientists and entrepreneurs who contemplate developing nanomedicine products face several unique challenges in addition to many of the traditional hurdles of product development. In this review we analyze the major physicochemical, biologic and functional characteristics of several nanomedicine products on the market and explore the question of what made them unique. What made them successful? We also focus on the regulatory challenges faced by nanomedicine product developers. Based on these analyses, we propose the factors that are most likely to contribute to the success of nanomedicine products.

The Atlantic salmon genome provides insights into rediploidization

USDA-ARS?s Scientific Manuscript database

The common ancestor of salmonids underwent an autotetraploid whole genome duplication event (Ss4R) approximately eighty million years ago, which provides unique opportunities to study the early evolutionary fate of a duplicated vertebrate genome in different extant lineages. Here, we present a high ...

Re-Imagining the (Un)Familiar: Feminist Pedagogy in Rural Spaces

ERIC Educational Resources Information Center

Wagner, Anne

2014-01-01

Little attention has been directed towards post-secondary education in rural spaces, instead conceptualising university study primarily as an urban phenomenon. Challenging dominant conceptions of rural areas as backwards, conservative, poverty stricken and isolated, this article investigates the unique opportunities associated with rural…

Measured Behavior and Thermal Gradients in Innovative Bridge Piers.

DOT National Transportation Integrated Search

1999-02-24

Construction of the U.S. 183 elevated highway in Austin, Texas, provided a unique opportunity to investigate the behavior of two types of innovative concrete piers. Tied Y shape piers were used to support mainlane spans. They were cast in situ with s...

ADDRESSING HUMAN EXPOSURE TO AIR POLLUTANTS AROUND BUILDINGS IN URBAN AREAS WITH COMPUTATIONAL FLUID DYNAMICS (CFD) MODELS

EPA Science Inventory

Computational Fluid Dynamics (CFD) simulations provide a number of unique opportunities for expanding and improving capabilities for modeling exposures to environmental pollutants. The US Environmental Protection Agency's National Exposure Research Laboratory (NERL) has been c...

Journal Club Format Emphasizing Techniques of Critical Reading.

ERIC Educational Resources Information Center

Woods, James R., Jr.; Winkel, Craig E.

1982-01-01

The journal club format offers the resident a unique opportunity to develop specific skills in reading, comprehending, and evaluating medical literature. A course designed for residents in obstetrics and gynecology at the Letterman Army Medical Center and at the University of Cincinnati is described. (MLW)

Aligning the Stars

ERIC Educational Resources Information Center

Thomas, Jeff; White, Katie

2012-01-01

Science Night--everybody wants one, but how does a teacher make it happen? To promote connections between schools, families, and communities, the authors organized a unique learning opportunity by combining three community partners' efforts and strengths. The school's Parent Teacher Association (PTA) coordinated and sponsored a science night for…

Planning Programs for Transescents.

ERIC Educational Resources Information Center

Eichhorn, Donald H.

"Transescents" -- the prefix "trans" meaning "to go across" and the suffix "escent" meaning "to become something" -- are young people in transition from childhood to adolescence. The middle school organization presents educators with an opportunity for improved educational processes uniquely suited to students of this age group. Transescents are…

Students participate in Congressional Night

NASA Technical Reports Server (NTRS)

1997-01-01

Middle school students were offered a unique opportunity at Stennis Space Center to speak real-time through audio and visual means to NASA scientists in Washington D.C., about numerous research projects, such as the Martian meteorite NASA researchers claim contains fossilized proof that life existed on Mars.

The ecology of carrion decomposition

USDA-ARS?s Scientific Manuscript database

Carrion, or the remains of dead animals, is something that most people would like to avoid. It is visually unpleasant, emits foul odors, and may be the source of numerous pathogens. Decomposition of carrion, however, provides a unique opportunity for scientists to investigate how nutrients cycle t...

Developing Intercultural Competence and Global Citizenship through International Experiences: Academics' Perceptions

ERIC Educational Resources Information Center

Trede, Franziska; Bowles, Wendy; Bridges, Donna

2013-01-01

International education is a key priority for Australian universities, government and employer groups. For students, an international professional experience is uniquely placed in providing opportunities for developing intercultural learning, intercultural competence and global citizenship. Employers see graduates with international experiences as…

Knowledge-Driven Design of Virtual Patient Simulations

ERIC Educational Resources Information Center

Vergara, Victor; Caudell, Thomas; Goldsmith, Timothy; Panaiotis; Alverson, Dale

2009-01-01

Virtual worlds provide unique opportunities for instructors to promote, study, and evaluate student learning and comprehension. In this article, Victor Vergara, Thomas Caudell, Timothy Goldsmith, Panaiotis, and Dale Alverson explore the advantages of using virtual reality environments to create simulations for medical students. Virtual simulations…

Enhancing moist forest restoration opportunities in riparian systems

Treesearch

Theresa Benavidez Jain; Russell T. Graham

2004-01-01

In northern Rocky Mountain moist forests, riparian systems contain many attributes that create unique biophysical conditions that alter disturbances and microenvironments; thus creating distinct forest structures, species composition, and management challenges. For example, browsing, limited opening size, competition from surrounding ground vegetation, high soil...

Training future chefs at Opryland.

PubMed

1998-08-01

Dina Starks is the culinary apprentice coordinator at Opryland Hotel Convention Center in Nashville, Tenn. Her apprentices have the unique opportunity to practice the culinary arts at the largest hotel convention center in the world, in a setting that has 15 restaurants and nearly 3,000 rooms.

76 FR 22001 - National Park Week, 2011

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-20

... Nation's collective health and spirit. These places preserve our unique history and iconic symbols. They... of our land. They offer opportunities for wholesome outdoor recreation, which can improve the health... this legacy with the America's Great Outdoors Initiative, designed to create a 21st-century...

Flight Mechanics Experiment Onboard NASA's Zero Gravity Aircraft

ERIC Educational Resources Information Center

Matthews, Kyle R.; Motiwala, Samira A.; Edberg, Donald L.; García-Llama, Eduardo

2012-01-01

This paper presents a method to promote STEM (Science, Technology, Engineering, and Mathematics) education through participation in a reduced gravity program with NASA (National Aeronautics and Space Administration). Microgravity programs with NASA provide students with a unique opportunity to conduct scientific research with innovative and…

Idea Bank: Steps to Visibility.

ERIC Educational Resources Information Center

Music Educators Journal, 1983

1983-01-01

Unique ideas about how to maintain interest in musicals, concerts, and other music performances are described. For example, Project Parent Awareness encouraged parent participation in children's music education and the Akron (Ohio) All-City Festivals of Music provided students with performing opportunities under well-known conductors. (CS)

Promoting Language Development through Movement

ERIC Educational Resources Information Center

Schilling, Tammy; McOmber, Kelly; Mabe, Kathy; Beasley, Bess; Funkhouser, Shari; Martinez, Layvette

2006-01-01

The purpose of this article is to share with educators the broad developmental benefits, specific challenges, and helpful hints regarding outdoor play for preschoolers, particularly those with limited English proficiency (LEP). In this article, the authors found, that physical play provides some unique opportunities for learning, especially for…

Neuroanatomical Correlates of Intelligence

ERIC Educational Resources Information Center

Luders, Eileen; Narr, Katherine L.; Thompson, Paul M.; Toga, Arthur W.

2009-01-01

With the advancement of image acquisition and analysis methods in recent decades, unique opportunities have emerged to study the neuroanatomical correlates of intelligence. Traditional approaches examining global measures have been complemented by insights from more regional analyses based on pre-defined areas. Newer state-of-the-art approaches…

Soil-plant-microbial relations in hydrothermally altered soils of Northern California

USDA-ARS?s Scientific Manuscript database

Soils developed on relict hydrothermally altered soils throughout the Western United States present unique opportunities to study the role of geology on above and belowground biotic activity and composition. Soil and vegetation samples were taken at three unaltered andesite and three hydrothermally ...

Serving the Public Good

ERIC Educational Resources Information Center

Greene, Jennifer C.

2010-01-01

This discussion foregrounds four key issues engaged by the articles presented in this special issue: the unique challenges and opportunities of environmental education evaluation, how to think well about the evaluation approaches and purposes that best match this domain, evaluation capacity building in environmental education and action, and…

Alternative Education, Not Alternative Location

ERIC Educational Resources Information Center

Mills, Anna-Marie; O'Dwyer, Kevin

2007-01-01

The Adventure Based Learning Experience (ABLE) program is designed for students who require a non-traditional approach to learning with varied program delivery options or need a flexible learning landscape. This unique experiential learning program provides students from Mississauga and Brampton the opportunity to "learn from doing" in…

Teaching Geographic Field Methods Using Paleoecology

ERIC Educational Resources Information Center

Walsh, Megan K.

2014-01-01

Field-based undergraduate geography courses provide numerous pedagogical benefits including an opportunity for students to acquire employable skills in an applied context. This article presents one unique approach to teaching geographic field methods using paleoecological research. The goals of this course are to teach students key geographic…

The Cage-Busting Teacher

ERIC Educational Resources Information Center

Hess, Frederick M.

2015-01-01

"The Cage-Busting Teacher" adopts the logic of "Cage-Busting Leadership" and applies it to the unique challenges and opportunities of classroom teachers. Detailed, accessible, and thoroughly engaging, it uncovers the many ways in which teachers can break out of familiar constraints in order to influence school and classroom…

The Instructor as College Marketing Representative.

ERIC Educational Resources Information Center

Haddon, Susan

In response to dwindling enrollments and increasing competition from other postsecondary institutes and private training schools, the Southern Alberta Institute of Technology (SAIT) has developed a marketing plan to take advantage of existing opportunities. SAIT's Marketing Department focuses on developing a strong and unique institutional image…

International Multidisciplinary Research and Education: A Mountain Geography Perspective

ERIC Educational Resources Information Center

Bishop, Michael P.

2009-01-01

Collaborative international research projects represent excellent opportunities for students to obtain unique and life-altering educational experiences. Dynamic interactions with people from a variety of countries, institutions, and departments, in diverse situations, provides students with new perspectives, encourages them to operate in a…

Shrinking the Supply Chain for Implantable Coronary Stent Devices.

PubMed

Moore, Sean S; O'Sullivan, Kevin J; Verdecchia, Francesco

2016-02-01

Stenting treatments for the management of disease in the heart, arterial and venous systems, biliary ducts, urethras, ureters, oesophageal tract and prostate have made enormous technical advances since their introduction into clinical use. The progression from metallic to polymer based bio-absorbable stents, coupled with the advances in additive manufacturing techniques, present a unique opportunity to completely re-envision the design, manufacture, and supply chain of stents. This paper looks at current stenting trends and proposes a future where the stent supply chain is condensed from ~150 days to ~20 min. The Cardiologist therefore has the opportunity to become a designer, manufacturer and user with patients receiving custom stents specific to their unique pathology that will be generated, delivered and deployed in the Cath-lab. The paper will outline this potentially revolutionary development and consider the technical challenges that will need to be overcome in order to achieve these ambitious goals. A high level overview of the generating eluting stents in situ program-GENESIS-is outlined including some early experimental work.

OLAM: A wearable, non-contact sensor for continuous heart-rate and activity monitoring.

PubMed

Albright, Ryan K; Goska, Benjamin J; Hagen, Tory M; Chi, Mike Y; Cauwenberghs, G; Chiang, Patrick Y

2011-01-01

A wearable, multi-modal sensor is presented that can non-invasively monitor a patient's activity level and heart function concurrently for more than a week. The 4 in(2) sensor incorporates both a non-contact heartrate sensor and a 5-axis inertial measurement unit (IMU), allowing simultaneous heart, respiration, and movement monitoring without requiring physical contact with the skin [1]. Hence, this Oregon State University Life and Activity Monitor (OLAM) provides the unique opportunity to combine motion data with heart-rate information, enabling assessment of actual physical activity beyond conventional movement sensors. OLAM also provides a unique platform for non-contact sensing, enabling the filtering of movement artifacts generated by the non-contact capacitive interface, using the IMU data as a movement noise channel. Intended to be used in clinical trials for weeks at a time with no physician intervention, the OLAM allows continuous non-invasive monitoring of patients, providing the opportunity for long-term observation into a patient's physical activity and subtle longitudinal changes.

Two Commemorative Expeditions to Celebrate the Return to Totality

NASA Astrophysics Data System (ADS)

Thompson, Kristen; English, Tom

2018-01-01

Throughout history, total solar eclipses have generated excitement across the scientific community, as they provide a unique opportunity to study the Sun’s corona. Occurrences of such events have prompted many American astronomy programs to organize expeditions aimed at studying and photographing the eclipse. Only two observing stations from any of the major 19th and early 20th century eclipse expeditions were once again found in the path of totality of the 21 August 2017 Great American Eclipse. These stations, one in Newberry, SC and the other in Winnsboro, SC, were located in the shadow of the 28 May 1900 eclipse that passed through the southeastern United States from New Orleans to Norfolk. To celebrate this unique opportunity, we organized two expeditions that travelled to these towns to commemorate their return to totality. In this talk, I will describe the circumstances of the 1900 solar eclipse, our modern expeditions, and our effort to bring this eclipse history to life for the community.

Anxiety Sensitivity Index (ASI-3) subscales predict unique variance in anxiety and depressive symptoms.

PubMed

Olthuis, Janine V; Watt, Margo C; Stewart, Sherry H

2014-03-01

Anxiety sensitivity (AS) has been implicated in the development and maintenance of a range of mental health problems. The development of the Anxiety Sensitivity Index - 3, a psychometrically sound index of AS, has provided the opportunity to better understand how the lower-order factors of AS - physical, psychological, and social concerns - are associated with unique forms of psychopathology. The present study investigated these associations among 85 treatment-seeking adults with high AS. Participants completed measures of AS, anxiety, and depression. Multiple regression analyses controlling for other emotional disorder symptoms revealed unique associations between AS subscales and certain types of psychopathology. Only physical concerns predicted unique variance in panic, only cognitive concerns predicted unique variance in depressive symptoms, and social anxiety was predicted by only social concerns. Findings emphasize the importance of considering the multidimensional nature of AS in understanding its role in anxiety and depression and their treatment. Copyright © 2013 Elsevier Ltd. All rights reserved.

Co-production of Snow Projections for a Study of Snow Persistence Projections for the American Wolverine Gulo gulo

NASA Astrophysics Data System (ADS)

Ray, A. J.; Barsugli, J. J.; Guinotte, J. M.; Livneh, B.; Dewes, C.; Rangwala, I.; Heldmyer, A.; Torbit, S.

2017-12-01

This presentation will describe the efforts of climate scientists to work with the US Fish and Wildlife Service (FWS) to provide analysis of future snow persistence to support a Species Status Assessment (SSA) for the American wolverine (Gulo gulo), under the Endangered Species Act (ESA). The project has been a research to application (R2A) study, aimed directly at the FWS needs, and in regular collaboration with FWS Region 6 personnel to discuss and agree on the choice downscaled projections to represent a range of plausible futures, and other methodological choices including use of high resolution (250m) physical hydrology modeling. FWS sought improved information on which to base a court-ordered re-evaluation of the conclusions of a previous SSA, due in 12 months, necessitating a quick turn-around for the snow research. The goal was to improve upon the the previous evaluation of snow persistence, both in understanding of the range of uncertainty and by using new snow modeling at spatial scales intended to be more relevant to both physical snowpack processes and to making inferences about potential wolverine denning opportunity. This project was embedded both in a specific legal/regulatory process and also in a broader FWS interest in building body of science for snow-dependent species that might support other ESA processes. Results of the co-production included new scientific questions and analytic approaches that arose from the interaction between climate scientists and ecologists. The fine spatial scales of the analysis compared to previous work allowed new hypotheses to be articulated, but also led to significant issues in the interpretation of the snow model output. This presentation will discuss key issues that arose in the collaboration between scientists and the managers developing the SSA, including the managing the independence of the science while remaining in a co-production mode, the challenges of the rapid time frame, and the challenges transitioning findings from a more academic and research framework to the demands of applied resource management.

A SWOT analysis of the physiotherapy profession in Kuwait.

PubMed

MacPherson, Meghan M; MacArthur, Lauren; Jadan, Patrick; Glassman, Leah; Bouzubar, Fawzi F; Hamdan, Elham; Landry, Michel D

2013-03-01

Since the end of the Gulf War in 1991, Kuwait has become one of the wealthiest countries in the world and one that has a highly socialized health-care system. This rapid growth and socio-economic development appears to have had a negative impact on the health of its people. As such, the profession of physiotherapy may be in a unique position to address this issue by providing health behaviour interventions and promoting healthy lifestyles. The purpose of this study was to explore the current state of physiotherapy in Kuwait and provide recommendations for future development and growth. Using a qualitative research approach, we conducted 17 key informant interviews (clinicians, administrators and other key stakeholders) in Kuwait. The strengths, weaknesses, opportunities and threats framework was then used to categorize the emerging themes and provide a basis for a strategic direction for the profession. Informants reported that strengths included funding for services and motivation of professionals. Weaknesses included education and professional resources, marketing/advocacy, standardization and regulation of practice. Opportunities discussed were untapped demand for physiotherapy services, internal development and evolution of the physiotherapy association, along with professional collaboration. Threats addressed included low public awareness of physiotherapy, challenges with inter-professional practice/communication, and cultural perspectives of healthy lifestyles. Our research indicates that many unique opportunities exist for physiotherapists in Kuwait. Further development and evolution of Kuwait's physiotherapy professional association could facilitate efforts to advocate for the profession, initiate standards of practice and provide enhanced opportunities for professional collaboration. Copyright © 2012 John Wiley & Sons, Ltd.

Implementing the new HEDIS hypertension performance measure.

PubMed

Sennett, C

2000-04-01

There is a problem with blood pressure control in the United States--a problem with significant implications for the health and welfare of the populace. This problem is bigger than managed care, but managed care organizations have both unique opportunities and unique obligations to address it. NCQA has responded to this problem, and to the opportunity for better care implicit in it, by introducing into HEDIS a measure that focuses on hypertension control. This measure will add pressure to health plans to address the problem of hypertension control, but it also will create the opportunity for positive recognition for those plans that succeed. The HEDIS hypertension measure is well grounded in both the science of medicine and the science of measurement. But HEDIS measurement alone will not create change. To effect change will require analysis of the problems that limit the delivery of effective care to patients with hypertension. It will require measurement of the success of the key processes of care upon which effective care depends. And it will require response--rational, focused, and operationally effective. These, in turn, will challenge key managers in health plans. Medical directors will have to influence provider behavior. Pharmacy directors will have to leverage pharmacy resources to support efforts to change provider and enrollee behaviors. And QA directors will have to manage a challenging set of measurement activities, from which plans' efforts to improve will be launched. The next few years will not be easy--demands for improvement increase annually, and resources are every year more scarce. Yet the goal is worth the struggle--to transform an industry that the public perceives to be interested in limiting care into one that the public turns to for assurance that care represents high value. Responding effectively to the HEDIS hypertension measure creates a unique opportunity for managed care--to demonstrate to the public that managed care is leading national efforts to improve quality for 50 million Americans needlessly at risk for heart disease and stroke, and in doing so, to demonstrate its commitment to health maintenance--the very foundation of managed care.

Starting a New Language Education Program

ERIC Educational Resources Information Center

Harris, Kathy

2015-01-01

Early years and primary teachers have a unique opportunity to apply their strong teaching practices, classroom management and understanding of childhood literacy development to teaching a language. This paper reports on a project from Independent Schools Queensland to increase language programs in schools by retraining classroom teachers.…

A Model for Designing Library Instruction for Distance Learning

ERIC Educational Resources Information Center

Rand, Angela Doucet

2013-01-01

Providing library instruction in distance learning environments presents a unique set of challenges for instructional librarians. Innovations in computer-mediated communication and advances in cognitive science research provide the opportunity for designing library instruction that meets a variety of student information seeking needs. Using a…

Cluster Analysis of Adolescent Blogs

ERIC Educational Resources Information Center

Liu, Eric Zhi-Feng; Lin, Chun-Hung; Chen, Feng-Yi; Peng, Ping-Chuan

2012-01-01

Emerging web applications and networking systems such as blogs have become popular, and they offer unique opportunities and environments for learners, especially for adolescent learners. This study attempts to explore the writing styles and genres used by adolescents in their blogs by employing content, factor, and cluster analyses. Factor…

Innovative Voices in Education: Engaging Diverse Communities

ERIC Educational Resources Information Center

Kugler, Eileen Gale, Ed.

2012-01-01

Diverse schools offer enriched academic and social environments, as students and families of different backgrounds and experiences provide a vibrant mosaic of insights, perspectives, and skills. To take advantage of the unique opportunities that diversity brings, schools must value and effectively connect with students and families of all…

Literacy Coaching: Engaging and Learning with Teachers

ERIC Educational Resources Information Center

Dozier, Cheryl L.

2008-01-01

Literacy coaching, a unique and generative opportunity to engage with and learn from teachers, is currently viewed as a powerful intervention to increase student literacy achievement. This article focuses on eight principles for responsive literacy coaching. To build trusting relationships, coaches engage with teachers in literacy events, confirm…

Learning Emotional Understanding and Emotion Regulation through Sibling Interaction

ERIC Educational Resources Information Center

Kramer, Laurie

2014-01-01

Research Findings: Young children's relationships with their sisters and brothers offer unique and important opportunities for learning about emotions and developing emotional understanding. Through a critical analysis, this article examines sibling interaction in 3 different but normative contexts (conflict/conflict management, play, and…

If Not Us, Who? Social Media Policy and the Ischool Classroom

ERIC Educational Resources Information Center

Nathan, Lisa P.; MacGougan, Alice; Shaffer, Elizabeth

2014-01-01

Social networking tools offer opportunities for innovative, participative pedagogical practice within traditional institutional frameworks. However, tensions continue to develop within this space: between creativity and security, personal and professional identity, privacy and openness. We argue that iSchools are uniquely positioned to create…

Estimating the Nominal Response Model under Nonnormal Conditions

ERIC Educational Resources Information Center

Preston, Kathleen Suzanne Johnson; Reise, Steven Paul

2014-01-01

The nominal response model (NRM), a much understudied polytomous item response theory (IRT) model, provides researchers the unique opportunity to evaluate within-item category distinctions. Polytomous IRT models, such as the NRM, are frequently applied to psychological assessments representing constructs that are unlikely to be normally…

BIOLOGICAL EFFECTS OF UTAH VALLEY PARTICLES: A REVIEW

EPA Science Inventory

The Utah Valley provided a unique opportunity to evaluate the health effects of particulate matter (PM) in humans. The area has had intermittently high particle levels with the principal point source being a steel mill. Due to a labor dispute, the mill was shut down. The closu...

SMOOTHING THE PEAKS: SMART OUTLETS TO REDUCE BROWNOUTS ON MICRO-HYDROELECTRIC MINIGRIDS IN BHUTAN

EPA Science Inventory

Our proposed project provides a low cost solution for a problem faced by thousands of communities that are seeking to use renewable electricity for sustainable economic development. It also creates a unique opportunity for collaboration between university students from Humbol...

A single amino acid substitution in an ORANGE protein promotes carotenoid overaccumulation in arabidopsis

USDA-ARS?s Scientific Manuscript database

Carotenoids are crucial for plant growth and human health. The finding of ORANGE (OR) protein as a pivotal regulator of carotenogenesis offers a unique opportunity to comprehensively understand the regulatory mechanisms of carotenoid accumulation and develop crops with enhanced nutritional quality. ...

The Liguleless narrow mutation affects proximal distal signaling and leaf growth

USDA-ARS?s Scientific Manuscript database

How cells acquire competence to differentiate according to position is an essential question in developmental biology. Maize leaves provide a unique opportunity to study positional information. In the developing leaf primordium, a line is drawn across a field of seemingly identical cells. Above the ...

The Evolution of an Online Substance Abuse Counseling Certificate Program

ERIC Educational Resources Information Center

Crozier, Mary K.

2012-01-01

In the field of rehabilitation services, substance abuse counseling requires unique skills. Post-baccalaureate academic certificate programs offer professionals an opportunity to retool or expand their skills and meet licensure needs in this evolving field. East Carolina University's online Substance Abuse Counseling Certificate Program was…

Incorporating Collaborative Technologies into University Curricula: Lessons Learned

ERIC Educational Resources Information Center

Hunt, C. Steven; Smith, Lola B.; Chen, Minder

2010-01-01

Web-based collaboration tools and groupware are uniquely qualified to address the emerging business opportunities heretofore hindered by location barriers, constraints of time, and expensive travel costs. Global business enterprises are implementing online collaboration software to augment their face-to-face meetings and group decision making in…

The Rural School Principalship: Unique Challenges, Opportunities.

ERIC Educational Resources Information Center

Hill, Jonathan

1993-01-01

Presents findings based on author's research and experience as principal in California's Mojave Desert. Five basic characteristics distinguish the rural principalship: lack of an assistant principal or other support staff; assumption of other duties, including central office tasks, teaching, or management of another site; less severe student…

Early Learner Perceptions of the Attributes of Effective Preceptors

ERIC Educational Resources Information Center

Huggett, Kathryn N.; Warrier, Rugmini; Maio, Anna

2008-01-01

Medical education in the US has adapted to the shift of patient care from hospital to ambulatory settings by developing educational opportunities in outpatient settings. Faculty development efforts must acknowledge learners' perspectives to be effective in improving teaching and learning. Clinics provide important and unique learning…

Recouple: Natural Resource Strategies for Rural Economic Development.

ERIC Educational Resources Information Center

Thomas, Margaret G.

This source book provides guidance and technical assistance material on utilizing forest, agricultural, and scenic and wildlife resources for rural economic development. The document focuses on the uniqueness of existing rural resources for new enterprise opportunities. Natural resource-based economic development strategies are a means to…

Dilemmas and Discarded Leadership

ERIC Educational Resources Information Center

Dana, Joyce A.

2009-01-01

Women are challenged most by cultural norms, particularly sex-role norms, religious and political ideologies, and gender-structured opportunities that favor men. Although some stereotypes have loosened a bit, dilemmas remain for women who aspire to fill school district leadership positions. The author's predicament is not unique. It is something…

Differential Susceptibility to Prevention: GABAergic, Dopaminergic, and Multilocus Effects

ERIC Educational Resources Information Center

Brody, Gene H.; Chen, Yi-fu; Beach, Steven R. H.

2013-01-01

Background: Randomized prevention trials provide a unique opportunity to test hypotheses about the interaction of genetic predispositions with contextual processes to create variations in phenotypes over time. Methods: Using two longitudinal, randomized prevention trials, molecular genetic and alcohol use outcome data were gathered from more than…

Using Distance Education To Teach Educational Leadership.

ERIC Educational Resources Information Center

Van Patten, James J.; Holt, Carleton

Educational administrator preparation is facing challenges in keeping up with rapidly changing delivery systems, as well as dealing with a shortage of well-trained school principals and superintendents. Distance learning offers an opportunity to serve diverse populations with a focus on individual uniqueness, needs, and concerns. Technology can…

Recognizing Excellence: Pinging--Sound at Work

ERIC Educational Resources Information Center

Lindquist, William; Forsberg, Britt

2014-01-01

One author shares the unique opportunity to be immersed in the science of "sound at work" through participation in NOAA's (National Oceanic and Atmospheric Administration) Teacher at Sea Program. A third- through fifth-grade learning outcome within the Nature of Science section of the "Next Generation Science Standards"…

Antibacterial, antifungal and antiprotozoal activities of fungal communities present in different substrates from Antarctica

USDA-ARS?s Scientific Manuscript database

Antarctica is a pristine and extreme environment that represents a unique opportunity for taxonomic, ecological and biotechnological studies of the microorganisms. In the present work, the fungal communities of rhizosphere soil of Deschampsia antarctica, soil, ornithogenic soil, marine and lake sedi...

The Python Project: A Unique Model for Extending Research Opportunities to Undergraduate Students

ERIC Educational Resources Information Center

Harvey, Pamela A.; Wall, Christopher; Luckey, Stephen W.; Langer, Stephen; Leinwand, Leslie A.

2014-01-01

Undergraduate science education curricula are traditionally composed of didactic instruction with a small number of laboratory courses that provide introductory training in research techniques. Research on learning methodologies suggests this model is relatively ineffective, whereas participation in independent research projects promotes enhanced…

Why Demonstrations Matter

ERIC Educational Resources Information Center

Black, Richard

2005-01-01

With the current focus on constructivist perspectives, science demonstrations have fallen out of favor in some circles. Demonstrations are easy to do and offer many benefits and unique opportunities in the constructivist classroom. With careful use, demonstrations can be powerful teaching tools. A wonderful quality of a demonstration (or a series…

Scientific Writing: A Blended Instructional Model

ERIC Educational Resources Information Center

Clark, MaryAnn; Olson, Valerie

2010-01-01

Scientific writing is composed of a unique skill set and corresponding instructional strategies are critical to foster learning. In an age of technology, the blended instructional model provides the instrumental format for student mastery of the scientific writing competencies. In addition, the course management program affords opportunities for…

Morphological observation of the horseshoe kidney with special reference to the vascular system in 2 Japanese cadavers.

PubMed

Nakamura, Yoichi; Yi, Shuang-Qin; Iimura, Akira; Terayama, Hayato; Naito, Munekazu; Itoh, Masahiro

2005-11-01

Two cases of the horseshoe kidney in Japanese cadaver were reported in this paper. The kidneys and their associated vessels in the retroperitoneal cavity were carefully examined, and the histological examination of the isthmus was performed. In Case 1, four arteries arose from the abdominal aorta. One right and two left renal arteries were distributed to the apical, upper, middle and posterior regions of the kidney, respectively, and the artery of isthmus entered the lower segments and the isthmus. In Case 2, six arteries arose from the abdominal aorta. Among three arteries arose from the inferior end of the aorta and entered the lower segments and the isthmus. Histological study revealed that the isthmuses consisted of collecting tubes, glomeruli and urinary tubules and fibrous connective tissue. The incidence of the horseshoe kidney during the dissecting practice at Tokyo Medical University in a period of 24 years from 1980 to 2003 was estimated to be 0.16% (2 out of the 1,219 cadavers). The anatomical and embryological significance of this anomaly and its associated vascular system were discussed. And the histology of the parenchymal structure of the isthmus in the horseshoe kidney containing either fibrous connective tissue or renal parenchyma was also analyzed in this report.

Diverse growth hormone receptor gene mutations in Laron syndrome.

PubMed Central

Berg, M A; Argente, J; Chernausek, S; Gracia, R; Guevara-Aguirre, J; Hopp, M; Pérez-Jurado, L; Rosenbloom, A; Toledo, S P; Francke, U

1993-01-01

To better understand the molecular genetic basis and genetic epidemiology of Laron syndrome (growth-hormone insensitivity syndrome), we analyzed the growth-hormone receptor (GHR) genes of seven unrelated affected individuals from the United States, South America, Europe, and Africa. We amplified all nine GHR gene exons and splice junctions from these individuals by PCR and screened the products for mutations by using denaturing gradient gel electrophoresis (DGGE). We identified a single GHR gene fragment with abnormal DGGE results for each affected individual, sequenced this fragment, and, in each case, identified a mutation likely to cause Laron syndrome, including two nonsense mutations (R43X and R217X), two splice-junction mutations, (189-1 G to T and 71 + 1 G to A), and two frameshift mutations (46 del TT and 230 del TA or AT). Only one of these mutations, R43X, has been previously reported. Using haplotype analysis, we determined that this mutation, which involves a CpG dinucleotide hot spot, likely arose as a separate event in this case, relative to the two prior reports of R43X. Aside from R43X, the mutations we identified are unique to patients from particular geographic regions. Ten GHR gene mutations have now been described in this disorder. We conclude that Laron syndrome is caused by diverse GHR gene mutations, including deletions, RNA processing defects, translational stop codons, and missense codons. All the identified mutations involve the extracellular domain of the receptor, and most are unique to particular families or geographic areas. Images Figure 1 Figure 2 PMID:8488849

Mars exploration: bridging our past and future (Invited)

NASA Astrophysics Data System (ADS)

Bibring, J.

2009-12-01

If life ever arose beyond the Earth, it is likely to have occurred on Mars: this was the belief long before any diagnostic measurements could be made. When the Viking, then Voyager missions were launched, pioneering the scientific search for extraterrestrial life, the “Plurality of Worlds” remained the dominating mindset: the possibility that the Earth is not unique and that life is generic was embraced. The lack of evidence for habitable conditions on Mars, and then Titan, dramatically changed our view. More generally, decades of space exploration have consolidated a dialectical contrast between the large commonality in the origin of the planets and the huge diversity of their present conditions. What drives planetary evolution? Mars plays a unique role in deciphering the involved processes. It has undergone many stages of planetary evolution, and has preserved a record of even the most ancient ones. The ongoing space mission, in which NASA and ESA have joined their skills and expertises, are providing a fundamentally new insight into the History of Mars and specifically into the role water has played through time. In particular, if life ever started, we now know where to search for its evidence. We’ve moved beyond just image interpretation into the realm where specific hydrated minerals such as phyllosilicates - the fingerprints of habitability - can be definitively detected, located and their context characterized. We will present recent results from Mars, and scientific clues paving the quest for ancient perennial water and potential bio-relics. We will discuss reasons why global conditions might have caused the evolutionary pathways of Mars and Earth to diverge.

High-throughput analysis of Yersinia pseudotuberculosis gene essentiality in optimised in vitro conditions, and implications for the speciation of Yersinia pestis.

PubMed

Willcocks, Samuel J; Stabler, Richard A; Atkins, Helen S; Oyston, Petra F; Wren, Brendan W

2018-05-31

Yersinia pseudotuberculosis is a zoonotic pathogen, causing mild gastrointestinal infection in humans. From this comparatively benign pathogenic species emerged the highly virulent plague bacillus, Yersinia pestis, which has experienced significant genetic divergence in a relatively short time span. Much of our knowledge of Yersinia spp. evolution stems from genomic comparison and gene expression studies. Here we apply transposon-directed insertion site sequencing (TraDIS) to describe the essential gene set of Y. pseudotuberculosis IP32953 in optimised in vitro growth conditions, and contrast these with the published essential genes of Y. pestis. The essential genes of an organism are the core genetic elements required for basic survival processes in a given growth condition, and are therefore attractive targets for antimicrobials. One such gene we identified is yptb3665, which encodes a peptide deformylase, and here we report for the first time, the sensitivity of Y. pseudotuberculosis to actinonin, a deformylase inhibitor. Comparison of the essential genes of Y. pseudotuberculosis with those of Y. pestis revealed the genes whose importance are shared by both species, as well as genes that were differentially required for growth. In particular, we find that the two species uniquely rely upon different iron acquisition and respiratory metabolic pathways under similar in vitro conditions. The discovery of uniquely essential genes between the closely related Yersinia spp. represent some of the fundamental, species-defining points of divergence that arose during the evolution of Y. pestis from its ancestor. Furthermore, the shared essential genes represent ideal candidates for the development of novel antimicrobials against both species.

Fracture risk among older men: osteopenia and osteoporosis defined using cut-points derived from female versus male reference data.

PubMed

Pasco, J A; Lane, S E; Brennan, S L; Timney, E N; Bucki-Smith, G; Dobbins, A G; Nicholson, G C; Kotowicz, M A

2014-03-01

We explored the effect of using male and female reference data in a male sample to categorise areal bone mineral density (BMD). Using male reference data, a large proportion of fractures arose from osteopenia, whereas using female reference data shifted the fracture burden into normal BMD. The purpose of this study was to describe fracture risk associated with osteopenia and osteoporosis in older men, defined by areal BMD and using cut-points derived from male and female reference data. As part of the Geelong Osteoporosis Study, we followed 619 men aged 60-93 years after BMD assessments (performed 2001-2006) until 2010, fracture, death or emigration. Post-baseline fractures were radiologically confirmed, and proportions of fractures in each BMD category were age-standardised to national profiles. Based on World Health Organization criteria, and using male reference data, 207 men had normal BMD at the femoral neck, 357 were osteopenic and 55 were osteoporotic. Using female reference data, corresponding numbers were 361, 227 and 31. During the study, 130 men died, 15 emigrated and 63 sustained at least one fracture. Using male reference data, most (86.5 %) of the fractures occurred in men without osteoporosis on BMD criteria (18.4 % normal BMD, 68.1 % osteopenia). The pattern differed when female reference data were used; while most fractures arose from men without osteoporosis (88.2 %), the burden shifted from those with osteopenia (34.8 %) to those with normal BMD (53.4 %). Decreasing BMD categories defined increasing risk of fracture. Although men with osteoporotic BMD were at greatest risk, they made a relatively small contribution to the total burden of fractures. Using male reference data, two-thirds of the fractures arose from men with osteopenia. However, using female reference data, approximately half of the fractures arose from those with normal BMD. Using female reference data to define osteoporosis in men does not appear to be the optimal approach.

Community health workers and the Patient Protection and Affordable Care Act: an opportunity for a research, advocacy, and policy agenda.

PubMed

Shah, Megha K; Heisler, Michele; Davis, Matthew M

2014-02-01

Community health workers (CHWs), who have been shown to be effective in multiple roles in the provision of culturally appropriate health care in a variety of settings, have the potential to be important members of an interdisciplinary health care team. Recent efforts have started to explore how best to integrate CHWs into the health system. However, to date, there has been limited policy guidance, support, or evidence on how best to achieve this on a larger scale. The Patient Protection and Affordable Care Act (ACA), through several provisions, provides a unique opportunity to create a unified framework for workforce integration and wider utilization of CHWs. This review identifies four major opportunities to further the research, advocacy, and policy agenda for CHWs.

Strategic alliances in healthcare: opportunities for the Veterans Affairs healthcare system.

PubMed

Halverson, P K; Kaluzny, A D; Young, G J

1997-01-01

Strategic alliances are proving to be effective strategies for responding and adapting to changing environments, and as such they offer the U.S. Department of Veterans Affairs (VA) healthcare system valuable opportunities for accomplishing the goals of its major reorganization effort. This article begins with an examination of basic strategic-alliance structures that are employed across many different types of industries. Next, consideration is given to the ways in which these basic alliance structures may be adapted to the unique organizations and individuals that serve as providers, purchasers, and consumers of health services. Finally, this article explores how models of strategic alliance in healthcare can be tailored to the specific needs and constraints of the VA healthcare system through an examination of existing and potential alliance opportunities.

Ballistic mode Mercury orbiter missions.

NASA Technical Reports Server (NTRS)

Hollenbeck, G. R.

1973-01-01

The MVM'73 Mercury flyby mission will initiate exploration of this unique planet. No firm plans for follow-on investigations have materialized due to the difficult performance requirements of the next logical step, an orbiter mission. Previous investigations of ballistic mode flight opportunities have indicated requirements for a Saturn V class launch vehicle. Consequently, most recent effort has been oriented to use of solar electric propulsion. More comprehensive study of the ballistic flight mode utilizing Venus gravity-assist has resulted in identification of timely high-performance mission opportunities compatible with programmed launch vehicles and conventional spacecraft propulsion technologies. A likely candidate for an initial orbiter mission is a 1980 opportunity which offers net orbiter spacecraft mass of about 435 kg with the Titan IIIE/Centaur launch vehicle and single stage solid propulsion for orbit insertion.

Superparamagnetic iron oxide nanoparticles: promises for diagnosis and treatment of cancer

PubMed Central

Laurent, Sophie; Mahmoudi, Morteza

2011-01-01

During the last decade, significant scientific research efforts have led to a significant growth in understanding of cancer at the genetic, molecular, and cellular levels providing great opportunities for diagnosis and treatment of cancer diseases. The hopes for fast cancer diagnosis and treatment were significantly increased by the entrance of nanoparticles to the medical sciences. Nanoparticles are attractive due to their unique opportunities together with negligible side effects not only in cancer therapy but also in the treatment of other ailments. Among all types of nanoparticles, surface-engineered superparamagnetic iron oxide nanoparticles (SPIONs) have been attracted a great attention for cancer therapy applications. This review covers the recent advances in the development of SPIONs together with their opportunities and challenges, as theranosis agents, in cancer treatment. PMID:22199999

Summary of Key Issues Raised in the Technology for Early Awareness of Addiction and Mental Illness (TEAAM-I) Meeting.

PubMed

Baumel, Amit; Baker, Justin; Birnbaum, Michael L; Christensen, Helen; De Choudhury, Munmun; Mohr, David C; Muench, Fred; Schlosser, Danielle; Titov, Nick; Kane, John M

2018-05-01

Technology provides an unparalleled opportunity to remove barriers to earlier identification and engagement in services for mental and addictive disorders by reaching people earlier in the course of illness and providing links to just-in-time, cost-effective interventions. Achieving this opportunity, however, requires stakeholders to challenge underlying assumptions about traditional pathways to mental health care. In this Open Forum, the authors highlight key issues discussed in the Technology for Early Awareness of Addiction and Mental Illness (TEAAM-I) meeting-held October 13-14, 2016, in New York City-that are related to three identified areas in which technology provides important and unique opportunities to advance early identification, increase service engagement, and decrease the duration of untreated mental and addictive disorders.

The dynamic proliferation of CanSINEs mirrors the complex evolution of Feliforms

PubMed Central

2014-01-01

Background Repetitive short interspersed elements (SINEs) are retrotransposons ubiquitous in mammalian genomes and are highly informative markers to identify species and phylogenetic associations. Of these, SINEs unique to the order Carnivora (CanSINEs) yield novel insights on genome evolution in domestic dogs and cats, but less is known about their role in related carnivores. In particular, genome-wide assessment of CanSINE evolution has yet to be completed across the Feliformia (cat-like) suborder of Carnivora. Within Feliformia, the cat family Felidae is composed of 37 species and numerous subspecies organized into eight monophyletic lineages that likely arose 10 million years ago. Using the Felidae family as a reference phylogeny, along with representative taxa from other families of Feliformia, the origin, proliferation and evolution of CanSINEs within the suborder were assessed. Results We identified 93 novel intergenic CanSINE loci in Feliformia. Sequence analyses separated Feliform CanSINEs into two subfamilies, each characterized by distinct RNA polymerase binding motifs and phylogenetic associations. Subfamily I CanSINEs arose early within Feliformia but are no longer under active proliferation. Subfamily II loci are more recent, exclusive to Felidae and show evidence for adaptation to extant RNA polymerase activity. Further, presence/absence distributions of CanSINE loci are largely congruent with taxonomic expectations within Feliformia and the less resolved nodes in the Felidae reference phylogeny present equally ambiguous CanSINE data. SINEs are thought to be nearly impervious to excision from the genome. However, we observed a nearly complete excision of a CanSINEs locus in puma (Puma concolor). In addition, we found that CanSINE proliferation in Felidae frequently targeted existing CanSINE loci for insertion sites, resulting in tandem arrays. Conclusions We demonstrate the existence of at least two SINE families within the Feliformia suborder, one of which is actively involved in insertional mutagenesis. We find SINEs are powerful markers of speciation and conclude that the few inconsistencies with expected patterns of speciation likely represent incomplete lineage sorting, species hybridization and SINE-mediated genome rearrangement. PMID:24947429

Incentives in U.S. Charter Schools: For-Profit and Nonprofit Choices

ERIC Educational Resources Information Center

Brown, Heath

2008-01-01

This paper examines the relationship between policy, organizational type, and the utilization of extrinsic incentives. Charter school reform spread throughout the country in the 1990s, providing the unique opportunity to study over a thousand new public organizations and the innovative operational decisions they made. Traditional public schools…

75 FR 53007 - Gulf Opportunity Pilot Loan Program (GO Loan Pilot)

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-30

... Presidentially-declared disaster areas resulting from Hurricanes Katrina and Rita as well as the further... impacted by Hurricanes Katrina and Rita. Under this unique initiative, SBA provides its full (85%) guaranty.../ counties that have been Presidentially-declared as disaster areas resulting from Hurricanes Katrina and...

Collaboration within Student Design Teams Participating in Architectural Design Competitions

ERIC Educational Resources Information Center

Erbil, Livanur; Dogan, Fehmi

2012-01-01

This paper investigates design collaboration with reference to convergent and divergent idea generation processes in architectural design teams entering a design competition. Study of design teams offer a unique opportunity to investigate how creativity is fostered through collaborative work. While views of creativity often relate creativity to…

The Ocean as a Unique Therapeutic Environment: Developing a Surfing Program

ERIC Educational Resources Information Center

Clapham, Emily D.; Armitano, Cortney N.; Lamont, Linda S.; Audette, Jennifer G.

2014-01-01

Educational aquatic programming offers necessary physical activity opportunities to children with disabilities and the benefits of aquatic activities are more pronounced for children with disabilities than for their able-bodied peers. Similar benefits could potentially be derived from surfing in the ocean. This article describes an adapted surfing…

Belonging as a Guiding Principle in the Education of Adolescents

ERIC Educational Resources Information Center

Allen, Kelly A.; Bowles, Terence

2012-01-01

Belonging has been shown to have a significant impact on a range of factors associated with wellbeing. These areas include life satisfaction, general wellbeing, clinical depression, cognitive performance, academic outcomes, and physical health. Belonging is an important aspect of psychological functioning. Schools offer unique opportunities for…

Ethical Considerations for Educational Research in a Virtual World

ERIC Educational Resources Information Center

Girvan, C.; Savage, T.

2012-01-01

The combination of features in virtual worlds provides an opportunity to implement and research unique learning experiences. With increasing interest and activity from the educational research community, exploring virtual worlds for teaching and learning, there is a need to identify and understand the ethical implications of conducting research in…

3 CFR 8336 - Proclamation 8336 of January 6, 2009. Establishment of the Pacific Remote Islands Marine National...

Code of Federal Regulations, 2010 CFR

2010-01-01

... Napoleon wrasse (Chelinus), sharks of several species, and large schools of the Bumphead parrotfish.... All three islands afford unique opportunities to conduct climate change research at the equator, far... international significance: Wedge-tailed Shearwaters, Christmas Shearwaters, Red-tailed Tropicbirds, Brown...

HPV Vaccination Practices Among Juvenile Justice Facilities in the United States

PubMed Central

Henderson, Courtney E.; Rich, Josiah D.; Lally, Michelle A.

2010-01-01

The juvenile justice setting provides a unique opportunity to administer the human papillomavirus (HPV) vaccine to a high-risk, medically underserved population. We examined current HPV vaccination practices in the United States. Most states (39) offer the HPV vaccine to females committed to juvenile justice facilities. PMID:20413087

The Effects of Educational Delivery Methods on Knowledge Retention

ERIC Educational Resources Information Center

Turner, Craig; Turner, Kyle Dean

2017-01-01

In today's dynamic learning environment, educational delivery methods have become increasingly diverse. Using a unique opportunity to assess three types of course delivery--face-to-face, interactive television (iTV), and purely online delivery--the authors look at both initial knowledge acquisition and the retention of this knowledge. The results…

Rows=Wildlife Corridors: An Urban Resource.

ERIC Educational Resources Information Center

Young, Darrell D.

1983-01-01

Linear strips of land associated with highways, electrical transmission lines, gas/oil pipelines (called right-of-way or ROWs) are inhibited by a variety of wildlife and offer a unique opportunity to study the wildlife in the urban setting. Types of wildlife found in and importance of ROWs are discussed. (JN)

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

NETL's Hybrid Performance, or Hyper, facility is a one-of-a-kind laboratory built to develop control strategies for the reliable operation of fuel cell/turbine hybrids and enable the simulation, design, and implementation of commercial equipment. The Hyper facility provides a unique opportunity for researchers to explore issues related to coupling fuel cell and gas turbine technologies.

The "Virtual" Panel: A Computerized Model for LGBT Speaker Panels

ERIC Educational Resources Information Center

Beasley, Christopher; Torres-Harding, Susan; Pedersen, Paula J.

2012-01-01

Recent societal trends indicate more tolerance for homosexuality, but prejudice remains on college campuses. Speaker panels are commonly used in classrooms as a way to educate students about sexual diversity and decrease negative attitudes toward sexual diversity. The advent of computer-delivered instruction presents a unique opportunity to…

QuarkNet: A Unique and Transformative Physics Education Program

ERIC Educational Resources Information Center

Bardeen, Marjorie; Wayne, Mitchell; Young, M. Jean

2018-01-01

The QuarkNet Collaboration has forged nontraditional relationships among particle physicists, high school teachers, and their students. QuarkNet centers are located at 50+ universities and labs across the United States and Puerto Rico. We provide professional development for teachers and create opportunities for teachers and students to engage in…

The Effectiveness of Youth Financial Education: A Review of the Literature

ERIC Educational Resources Information Center

McCormick, Martha Henn

2009-01-01

In the current financial crisis, children and youth are uniquely impacted by household finance complexities. Moments of financial trouble are teachable opportunities for children and youth to learn about personal finance and to improve their own money management skills. However, comprehensive strategies for educating them about personal finance…

Research-able through Problem-Based Learning

ERIC Educational Resources Information Center

Annerstedt, Claes; Garza, Dan; Huang-DeVoss, Cammy; Lindh, Jacob; Rydmark, Martin

2010-01-01

This research project describes an attempt to move towards a more student centered and participatory approach on learning through problem-based storyboards (themes/scenarios) and a unique opportunity for students to have an academic cross-cultural exchange. The purpose of the study was to analyze students' conceptions of this approach on learning…

Acousto-Optic Tunable Filter for Time-Domain Processing of Ultra-Short Optical Pulses,

DTIC Science & Technology

The application of acousto - optic tunable filters for shaping of ultra-fast pulses in the time domain is analyzed and demonstrated. With the rapid...advance of acousto - optic tunable filter (AOTF) technology, the opportunity for sophisticated signal processing capabilities arises. AOTFs offer unique

Addressing Parental Vaccination Questions in the School Setting

ERIC Educational Resources Information Center

Luthy, Karlen E.; Burningham, Jana; Eden, Lacey M.; Macintosh, Janelle L. B.; Beckstrand, Renea L.

2016-01-01

School nurses work in a unique environment with key opportunities to address parental concerns and questions regarding their child's health. A common concern for parents during school enrollment is childhood vaccination safety and efficacy. As public health leaders, school nurses are well respected among parents, therefore school nurses are in a…

Catalan in the Twenty-First Century

ERIC Educational Resources Information Center

Urla, Jacqueline

2013-01-01

This special issue devoted to Catalonia--one of the most successful and longstanding language movements in Europe--gives a unique opportunity to understand some of the complex social dynamics engendered as language revival unfolds and to appreciate the value of in-depth interviewing, focus groups, and ethnographic work in making sometimes subtle…

Algal Biofuels Techno-Economic Analysis | Bioenergy | NREL

Science.gov Websites

Biofuels Techno-Economic Analysis Algal Biofuels Techno-Economic Analysis To promote an understanding of the challenges and opportunities unique to microalgae, NREL's Algae Techno-Economic Analysis group focuses on techno-economic analysis (TEA) for the production and conversion of algal biomass into

Gas and aerosol carbon in California: comparison of measurements and model predictions in Pasadena and Bakersfield.

EPA Science Inventory

Co-located measurements of fine particulate matter (PM2.5) organic carbon (OC), elemental carbon, radiocarbon (14C), speciated volatile organic compounds (VOCs),and OH radicals during the CalNex field campaign provide a unique opportunity to evaluate the Community Multiscale Air ...

Creating Time for Equity Together

ERIC Educational Resources Information Center

Renée, Michelle

2015-01-01

Iin urban communities across the nation, a broad range of partners have committed to reinventing educational time together to ensure equitable access to rich learning opportunities for all young people. Across the nation, education partners are using their creativity, commitment, and unique resources to create new school and system designs that…

The NASA Ground Network Vision for the Future

NASA Technical Reports Server (NTRS)

Clson, Roger N.; Matalavage, Jill E.; Taylor, David A.

2008-01-01

This paper will highlight the GN's mission, motivation, and future plans, specifically in relation to the increase of commercialization for routine services and partnership opportunities for routine and unique services with the goal that other agencies can benefit from our approach as they pursue their science and exploration goals.

An Examination of the Determinants of Top Management Support of Information Technology Projects

ERIC Educational Resources Information Center

Mahoney, Michael L.

2011-01-01

Despite compelling evidence that top management support promotes information technology project success, existing research fails to offer insight into the antecedents of top management support of such projects. This gap in the literature is significant since the exploitation of information technology offers organizations unique opportunities for…

Teaching U.S. History with an Eye to the World

ERIC Educational Resources Information Center

Talamante, Laura Emerson

2008-01-01

Preparing to teach a course outside one's field of specialty or even continental comfort zone provides a unique if somewhat daunting opportunity. With Western Civilization classes as the author's teaching experience for entry-level college courses, she approached teaching "The United States Since Reconstruction" with some trepidation. However,…

"Dine Bikeya": Teaching about Navajo Citizenship and Sovereignty

ERIC Educational Resources Information Center

Washington, Elizabeth Yeager; van Hover, Stephanie

2011-01-01

The Navajo Nation, comprising the largest land area allocated mainly to a Native American jurisdiction in the United States, offers a unique opportunity to enhance students' understandings of citizenship rights and sovereignty. For example, what does sovereignty mean on the reservation? What is the relationship between the Navajo Nation and the…

An Innovative Near-Peer Mentoring Model for Undergraduate and Secondary Students: STEM Focus

ERIC Educational Resources Information Center

Tenenbaum, Laura S.; Anderson, Margery K.; Jett, Marti; Yourick, Debra L.

2014-01-01

This study examined a novel mentoring model, "near-peer mentorship," that supports the development of mentee and mentor, incorporates established principles of mentoring, and offers unique opportunities to integrate research and teaching in a science, technology, engineering, and mathematics (STEM) internship. Using qualitative methods,…

Development of kairomone based control programs for cocoa pod borer

USDA-ARS?s Scientific Manuscript database

The Cocoa Pod Borer moth presents a unique opportunity to develop host volatile attractants for control strategies for the following reasons. First, knowing what volatiles are critical for host finding by females will allow for development of mass trapping and/or attract and kill strategies to cont...

Examining Willingness to Attack Critical Infrastructure Online and Offline

ERIC Educational Resources Information Center

Holt, Thomas J.; Kilger, Max

2012-01-01

The continuing adoption of technologies by the general public coupled with the expanding reliance of critical infrastructures connected through the Internet has created unique opportunities for attacks by civilians and nation-states alike. Although governments are increasingly focusing on policies to deter nation-state level attacks, it is unclear…

Fundulus as the Premier Teleost Model in Environmental Biology: Opportunities for New Insights Using Genomics

EPA Science Inventory

A strong foundation of basic and applied research documents that the estuarine fish Fundulus heteroclitus and related species are unique laboratory and field models for understanding how individuals and populations interact with their environment. In this paper we summarize an ex...

Towards an Understanding of Muslim American Adolescent High School Experiences

ERIC Educational Resources Information Center

Seward, Derek X.; Khan, Shaza

2016-01-01

The researchers conducted a grounded theory study to explore the experiences of Muslim American adolescents in high school. Findings indicate that students had to navigate unique challenges because of their religious faith, but those obstacles presented opportunities to confront bias and discrimination. Recommendations for how school counselors…

Education News at NASA

NASA Technical Reports Server (NTRS)

2004-01-01

NASA s challenging missions provide unique opportunities for engaging and educating America s youth, the next generation of explorers. Led by Chief Education Officer Dr. Adena Williams Loston, the Agency coordinates education programs for students, faculty, and institutions in order to help inspire and motivate the scientists and engineers of the future.

Ensuring Moral Development in Physical Education

ERIC Educational Resources Information Center

Schwamberger, Benjamin; Wahl-Alexander, Zachary; Ressler, James

2017-01-01

The physical education setting offers a unique opportunity to educate the whole student. It would seem appropriate then, that physical education teachers place strong emphasis on the aspect of moral development and character building, however, this can be a challenging task. To accomplish this, the purpose of this article is to provide strategies…

Manipulations of soil microbiota for C sequestration and mitigation of greenhouse gas emissions in managed systems

USDA-ARS?s Scientific Manuscript database

Soil microbes dominate processes that regulate soil trace gas emissions and soil C and N dynamics. Intensive management in agroecosystems provides unique opportunities to assess the effectiveness of microbial manipulations to enhance soil C retention and reduce trace gas emissions. While reduced til...

Reflections on Doing Geography: Learning Observations from the Fourth Grade

ERIC Educational Resources Information Center

Delahunty, Tina

2010-01-01

The Nature Conservancy's (TNC) Orchard Bog site in Shady Valley, Tennessee, is a unique Appalachian mountain bog that provides many opportunities for student exploration. A biogeographer, a field technician, two biologists, and a historian combined their expertise to teach 100 fourth graders how historians and scientists learn about past…

A Contract for Excellence in Scientific Education: May I Have Your Signature Please?

ERIC Educational Resources Information Center

Tate, William F.; Malancharuvil-Berkes, Elizabeth

2006-01-01

Recent advances in biology and digital technology represent unique opportunities for teacher educators to rethink the programmatic experiences of prospective secondary science and mathematics teachers. This article discusses the importance of teacher education programs that connect mathematics and science where appropriate, recognize the…

New Directions in Tribal Early Childhood Programs

ERIC Educational Resources Information Center

Bohanon, Kelli

2016-01-01

This article explores the efforts of tribal communities building more coordinated and effective early childhood systems by taking advantage of federal funding opportunities and partnerships. Given a new level of understanding and response from federal agencies regarding the unique nature of tribal communities, efforts are being made to acknowledge…

Integrating Technology into the Curriculum for "At-Risk" Youth

ERIC Educational Resources Information Center

McCall, Denise

2009-01-01

This Independent Learning Project (ILP) discusses the best practices in educational technology to improve the behavior, instruction, and learning of at-risk youth, for whom technology offers unique opportunities. Research is compiled from numerous scholarly print and online sources. A guide for teachers provides detailed strategies, software…

Unique Opportunities: Influence of Study Abroad on Black Students

ERIC Educational Resources Information Center

Lee, Jasmine; Green, Qiana

2016-01-01

This research adds to the dearth of literature examining the experiences of Black students who study abroad. Additionally, this project extends the literature on the influence of diasporic travel on US Black undergraduate students. Because study abroad has positive benefits for student learning and development (Brux & Fry, 2010), targeted…

The School Leader's Guide to Social Media

ERIC Educational Resources Information Center

Williamson, Ronald; Johnston, J. Howard

2012-01-01

Social media has exploded onto American culture--including our schools--giving educators a unique opportunity to shape this phenomenon into a powerful tool for improving educational leadership practices. With real-world examples and practical tips, this essential guide shows school leaders how to address both the potential benefits and common…

Using NMR to Expand Chemistry Research and Educational Experiences at North Carolina Central University, an Historically Black University

DTIC Science & Technology

analytical chemistry . Most students do not get hands-on training with an NMR within their classroom or laboratory courses. The NMR will provide...unique opportunities to our students as they train to become the next generation of scientists, doctors, and engineers .

Integrating Multicultural Education: Activities to Celebrate the Chinese New Year

ERIC Educational Resources Information Center

Bian, Wei; Wang, Jianyu; McKinley, Betsy

2009-01-01

Holiday and festival celebrations are a unique form of cultural expression. Physical activities associated with cultural traditions offer the perfect opportunity for physical educators to integrate interdisciplinary teaching in their programs. This article focuses on the application of a multicultural perspective by introducing 12 station tasks…

Utilizing Science Outreach to Foster Professional Skills Development in University Students

ERIC Educational Resources Information Center

Eng, Edward; Febria, Catherine

2011-01-01

Students seek unique experiences to obtain and enhance professional development skills and to prepare for future careers. Through the Let's Talk Science Partnership Program (LTSPP), a voluntary science outreach program at University of Toronto Scarborough, students are given the opportunity to continually improve on skills which include: the…

The Validity of Two Education Requirement Measures

ERIC Educational Resources Information Center

van der Meer, Peter H.

2006-01-01

In this paper we investigate the validity of two education requirement measures. This is important because a key part of the ongoing discussion concerning overeducation is about measurement. Thanks to the Dutch Institute for Labour Studies, we have been given a unique opportunity to compare two education requirement measures: first, Huijgen's…

Understanding and Evaluating English Learners' Oral Reading with Miscue Analysis

ERIC Educational Resources Information Center

Latham Keh, Melissa

2017-01-01

Miscue analysis provides a unique opportunity to explore English learners' (ELs') oral reading from an asset-based perspective. This article focuses on insights about eight adolescent ELs' oral reading patterns that were gained through miscue analysis. The participants' miscues were coded with the Reading Miscue Inventory, and participants were…

Dating sediment in a fast sedimentation reservoir using 137Cs and 210Pb

USDA-ARS?s Scientific Manuscript database

Over 10,000 reservoirs have been constructed in agricultural watersheds in the United States since the 1940s to control floods and sediments. Reservoir sedimentation records provide a unique opportunity to retrospectively study the effects of land use changes and climate variations on sediment produ...

Developing Practitioner-Scholars through University-School District Research Partnerships

ERIC Educational Resources Information Center

Ralston, Nicole C.; Tarasawa, Beth; Waggoner, Jacqueline M.; Smith, Rebecca; Naegele, Zulema

2016-01-01

University-community partnerships have gained popularity in the United States as a means of extending university research resources and collaborative opportunities. However, research-driven partnerships between universities and K-12 school districts that prioritize the research needs of K-12 schools are unique. Recently, education scholars have…

Partners in Learning

ERIC Educational Resources Information Center

Weaver, Andrew J.; Mueller, Andrea

2009-01-01

What happens when children and scientists learn together? A partnership is formed, that's what! This article describes how a university scientist and a teacher teamed up with a local fourth-grade teacher to provide a unique opportunity for students to observe real scientists at work and enhance their knowledge of weather at the same time. The…

The Promise for Geomorphic Discovery in the South.

ERIC Educational Resources Information Center

Mossa, Joann

1998-01-01

Presents an overview of current geomorphic research in the southern United States. Conveys that the limited historical effort offers both challenges and opportunities for conducting geomorphic work in the region; much is unknown about these unique landscapes. States applied and theoretical geomorphology will benefit the society and future of the…

An individual-based modeling approach to simulating recreation use in wilderness settings

Treesearch

Randy Gimblett; Terry Daniel; Michael J. Meitner

2000-01-01

Landscapes protect biological diversity and provide unique opportunities for human-nature interactions. Too often, these desirable settings suffer from extremely high visitation. Given the complexity of social, environmental and economic interactions, resource managers need tools that provide insights into the cause and effect relationships between management actions...

Establishing Quality Assurance in the South African Context

ERIC Educational Resources Information Center

Strydom, A. H.; Strydom, J. F.

2004-01-01

This paper provides perspectives on the unique challenges and opportunities facing the national auditing and accreditation system in South African higher education. In doing so, the quality assurance contexts of developed countries, Africa and South Africa are considered and the issues of uncertainty and conformity are highlighted. This is…

Literacy Instruction in the Wake of Common Core State Standards

ERIC Educational Resources Information Center

Barrett-Mynes, Jennifer

2013-01-01

As teachers modify their instruction to meet English Language Arts (ELA) Common Core State Standards (CCSS), how do these modifications influence literacy instruction and learning opportunities afforded to students? While the CCSS standardized objectives for literacy instruction, the enacted curriculum is uniquely shaped by teachers and their…

Creating New Identities in Design Education

ERIC Educational Resources Information Center

Mendoza, Hannah Rose; Bernasconi, Claudia; MacDonald, Nora M.

2007-01-01

An international education opportunity has been created for design students at West Virginia University. This experience is unique because it takes an interdisciplinary approach to design that exposes students to the idea of a larger design methodology common to design professions. Students take core courses with students from a variety of design…

Everybody Dreams: Preparing a New Generation. NASA Explorer Schools Project

ERIC Educational Resources Information Center

National Aeronautics and Space Administration, 2005

2005-01-01

NASA Explorer Schools provides unique opportunities for students and teachers by offering access to technology and resources that are seemingly beyond reach. Combining new technologies with NASA content, lesson plans, and real-world experiments enables teachers to enhance inquiry-based learning and augment student engagement. This publication…

The Neuroanatomy and Neuroendocrinology of Fragile X Syndrome

ERIC Educational Resources Information Center

Hessl, David; Rivera, Susan M.; Reiss, Allan L.

2004-01-01

Fragile X syndrome (FXS), caused by a single gene mutation on the X chromosome, offers a unique opportunity for investigation of gene-brain-behavior relationships. Recent advances in molecular genetics, human brain imaging, and behavioral studies have started to unravel the complex pathways leading to the cognitive, psychiatric, and physical…

Assessing Model Characterization of Single Source Secondary Pollutant Impacts Using 2013 SENEX Field Study Measurements

EPA Science Inventory

Aircraft measurements made downwind from specific coal fired power plants during the 2013 Southeast Nexus field campaign provide a unique opportunity to evaluate single source photochemical model predictions of both O3 and secondary PM2.5 species. The model did well at predicting...

Learning during Tourism: The Experience of Learning from the Tourist's Perspective

ERIC Educational Resources Information Center

Van Winkle, Christine M.; Lagay, Katya

2012-01-01

The purpose of the research described in the paper was to explore the learning experience that occurs during leisure tourism from the tourist's perspective. Learning throughout the lifespan occurs in diverse contexts and travel presents a unique learning environment enabling both unplanned and planned opportunities. The Husserlian phenomenology…

Denver Public Schools: Resegregation, Latino Style

ERIC Educational Resources Information Center

Lee, Chungmei

2006-01-01

The Denver Public Schools (DPS) provide a unique opportunity to study the dynamics of school segregation within the context of rapid demographic changes and key policy changes. This paper, the first of two reports, focuses on the dynamics of segregation, demographic changes, and implications for graduation rates in the Denver Public Schools. It…

Can Long John Silver Save the Humanities?

ERIC Educational Resources Information Center

Mendelson, Michael

2010-01-01

Given the serious decline in the number of undergraduates majoring in the humanities in general, and literature in particular, teachers of Children's Literature have a unique opportunity to serve their discipline by tapping the power of classroom dialogue to introduce students to the practical reasoning central to humanistic study. This essay…

Learning by Doing: Using an Online Simulation Game in an International Relations Course

ERIC Educational Resources Information Center

Epley, Jennifer

2016-01-01

Integrating interactive learning activities into undergraduate courses is one method for increasing student interest, engagement, and skills development. Online simulation games in particular offer students the unique applied opportunity to "learn by doing" in a virtual space to further their overall knowledge base and critical thinking…

Challenges and Opportunities for Learning Biology in Distance-Based Settings

ERIC Educational Resources Information Center

Hallyburton, Chad L.; Lunsford, Eddie

2013-01-01

The history of learning biology through distance education is documented. A review of terminology and unique problems associated with biology instruction is presented. Using published research and their own teaching experience, the authors present recommendations and best practices for managing biology in distance-based formats. They offer ideas…

SSSNOW Project: Helping Make Science Cool for Students

ERIC Educational Resources Information Center

Huff, Kenneth; Lange, Catherine

2010-01-01

In the atmosphere or on the ground, snow provides students with unique opportunities to discover winter weather patterns. Traditionally, when students study weather, it is limited to the collection of data one would see on a weather report. However, the interdisciplinary Students Synthesizing Snow data in Natural Objective Ways (SSSNOW) project…

On the long-term hydroclimatic sustainability of perennial bioenergy crop expansion over the United States

USDA-ARS?s Scientific Manuscript database

Large-scale cultivation of perennial bioenergy crops (e.g., miscanthus and switchgrass) offers unique opportunities to mitigate climate change through avoided fossil fuel use and associated greenhouse gas reduction. Although conversion of existing agriculturally intensive lands (e.g., maize and soy)...

A realistic meteorological assessment of perennial biofuel crop deployment: a southern Great Plains perspective

USDA-ARS?s Scientific Manuscript database

Utility of perennial bioenergy crops (e.g., switchgrass and miscanthus) offer unique opportunities to transition toward a more sustainable energy pathway due to their reduced carbon footprint, averted competition with food crops, and ability to grow on abandoned and degraded farmlands. Studies that ...

It's a Snap! An Inquiry-Based, Snapping Shrimp Bioacoustics Activity

ERIC Educational Resources Information Center

Fox, Bradley K.; Gorospe, Kelvin D.; Haverkort-Yeh, Roxanne D.; Rivera, Malia Ana J.

2013-01-01

This bioacoustics activity combines concepts in invertebrate taxonomy, animal communication, and acoustical physics while providing a unique opportunity for physics and biology teachers to collaborate and introduce their students to an exciting, interdisciplinary research field. Here, we propose a lab-and field-based activity that uses hydrophones…

Teaching Science in the Field. ERIC Digest.

ERIC Educational Resources Information Center

Landis, Carol

Teaching science in the field provides unique opportunities to investigate the natural world. As in the classroom, lessons designed to foster meaningful learning, provide hands-on activities, and promote student inquiry can be effectively implemented in the world's largest laboratories, the natural and built environments of the outdoors. This…

Integrating Social Neuroscience and Social Work: Innovations for Advancing Practice-Based Research

ERIC Educational Resources Information Center

Matto, Holly C.; Strolin-Goltzman, Jessica

2010-01-01

Throughout the social work profession, there is ongoing interest in building a social science agenda that can address the complex practice-based questions faced by social work professionals today. Methodological innovations and unique funding opportunities have already significantly advanced research on social work practice. Still, there is…

Gambel oak growth forms: Management opportunities for increasing ecosystem diversity

Treesearch

Scott R. Abella

2008-01-01

Gambel oak (Quercus gambelii) clones have several different growth forms in southwestern ponderosa pine (Pinus ponderosa) forests, and these growth forms each provide unique wildlife habitat and resource values. The purposes of this note are to review published growth-form classifications for Gambel oak, provide examples of...

Family Connections: Using Collaborative Partnerships to Support Dissemination

ERIC Educational Resources Information Center

DePanfilis, Diane

2015-01-01

Spreading and sustaining evidence-informed practice in child welfare is complex. In particular, putting in place an active dissemination strategy requires the recognition of these unique challenges. The purpose of this paper is to illustrate how collaborative partnerships between individuals and organizations may represent an opportunity for more…

Model for Presenting Resources in Scholar's Portal

ERIC Educational Resources Information Center

Feeney, Mary; Newby, Jill

2005-01-01

Presenting electronic resources to users through a federated search engine introduces unique opportunities and challenges to libraries. This article reports on the decision-making tools and processes used for selecting collections of electronic resources by a project team at the University of Arizona (UA) Libraries for the Association of Research…

Youth Purpose through the Lens of the Theory of Organizing Models of Thinking

ERIC Educational Resources Information Center

Arantes, Valeria; Araujo, Ulisses; Pinheiro, Viviane; Moreno Marimon, Montserrat; Sastre, Genoveva

2017-01-01

Purpose represents a unique opportunity for identifying and analyzing the complexity of human reasoning, considering that its constitution brings together cognitive, affective and social elements. In this article, we use the Theory of Organizing Models of Thinking (OMT), an epistemological and methodological approach based on developmental…

Using Information and Communication Technology (ICT) to the Maximum: Learning and Teaching Biology with Limited Digital Technologies

ERIC Educational Resources Information Center

Van Rooy, Wilhelmina S.

2012-01-01

Background: The ubiquity, availability and exponential growth of digital information and communication technology (ICT) creates unique opportunities for learning and teaching in the senior secondary school biology curriculum. Digital technologies make it possible for emerging disciplinary knowledge and understanding of biological processes…

Cross-Cultural Simulations in Teacher Education: Developing Empathy and Understanding

ERIC Educational Resources Information Center

Cruz, Barbara C.; Patterson, Jennifer

2005-01-01

Teacher training programs have recognized the importance of preparing future teachers for the unique opportunities and challenges that our multicultural societies and world provide. One method that is useful in sensitizing teachers to issues of diversity is cross-cultural simulations. By using kinesthetic and affective modes of learning,…

For Love or Money? Welfare Reform and Immigrant Naturalization

ERIC Educational Resources Information Center

Van Hook, Jennifer; Brown, Susan K.; Bean, Frank D.

2006-01-01

The Welfare Reform Act of 1996 generally restricted immigrants' eligibility for welfare to those who had naturalized. By increasing the salience of naturalization, the law provides a unique opportunity to examine how social and economic contexts of reception influence immigrants' pursuit of citizenship. This paper summarizes instrumental-legal…

Supporting Diverse Young Adolescents: Cooperative Grouping in Inclusive Middle-Level Settings

ERIC Educational Resources Information Center

Miller, Nicole C.; McKissick, Bethany R.; Ivy, Jessica T.; Moser, Kelly

2017-01-01

The middle level classroom presents unique challenges to educators who strive to provide opportunities that acknowledge learner diversity in terms of social, cognitive, physical, and emotional development. This is confounded even further within inclusive middle-school classrooms where the responsibility to differentiate instruction is even more…

Large-scale imaging of cortical network activity with calcium indicators.

PubMed

Ikegaya, Yuji; Le Bon-Jego, Morgane; Yuste, Rafael

2005-06-01

Bulk loading of calcium indicators has provided a unique opportunity to reconstruct the activity of cortical networks with single-cell resolution. Here we describe the detailed methods of bulk loading of AM dyes we developed and have been improving for imaging with a spinning disk confocal microscope.

Education for Sustainability: Exploring Teaching Practices and Perceptions of Learning Associated with a General Education Requirement

ERIC Educational Resources Information Center

Natkin, Lisa Watts

2016-01-01

Higher education institutions are increasingly interested in infusing sustainability content into their curricula. This can be accomplished through general education programs, which the University of Vermont recently established. The implementation of this new requirement created a unique opportunity to investigate sustainability- related teaching…

The Benefits of Implementing a Feedback Informed Treatment System within Counselor Education Curriculum

ERIC Educational Resources Information Center

Yates, Chad M.; Holmes, Courtney M.; Coe Smith, Jane C.; Nielson, Tiffany

2016-01-01

Counselor education departments have a unique opportunity to implement feedback informed treatment (FIT) systems that serve as continual assessment procedures by informing counselors, clients, supervisors and educators about client functioning and progress toward goals. These systems hold potential benefits within counselor training such as a…

Integrating Research and Story Writing.

ERIC Educational Resources Information Center

Scott-Simmons, Diana; Barker, Jeanne; Cherry, Nan

2003-01-01

Describes a storytelling unit that offers a unique opportunity for students to develop skills in telling and writing stories while enhancing their Internet research skills. Notes that these stories require writers to conduct research and use their imaginations to create a story plot and characters that hold the reader's and listener's interest.…

The Religious Studies Major and Liberal Education

ERIC Educational Resources Information Center

Liberal Education, 2009

2009-01-01

At a time when leaders in higher education are increasingly asking students to engage the large issues of life's meaning and to think critically and responsibly about their role in the world, religious studies offers unique opportunities. Other disciplines such as philosophy, literature, and the creative arts doubtlessly engage questions of…

Building Basic Therapeutic Skills: A Practical Guide for Current Mental Health Practice.

ERIC Educational Resources Information Center

Heaton, Jeanne Albronda

Each therapeutic contact provides unique opportunities to ameliorate suffering and cultivate change. This volume addresses the inherent struggle in therapy to create a therapeutic relationship and make the work compassionate, efficient, and effective. It provides assistance to students, supervisors, and educators in doing therapeutic work while…

Harvey Mudd College: Technology Integration Offers Unique Opportunities for Undergraduates.

ERIC Educational Resources Information Center

Barna, John; Winstead, Jim

1993-01-01

Describes undergraduate projects at Harvey Mudd College (California) that use advanced laboratory equipment and procedures normally reserved for graduate students. Examples are given in experimental biology (e.g., digital imaging and DNA analysis), in physics (e.g., using satellites to study earthquake faults), and in mathematics (e.g., teaching…

Raman spectroscopy in the analysis of cellulose nanomaterials

Treesearch

Umesh P. Agarwal

2017-01-01

Cellulose nanomaterials (CNs) are new types of materials derived from celluloses and offer unique challenges and opportunities for Raman spectroscopic investigations. CNs can be classified into the categories of cellulose nanocrystals (CNCs, also known as cellulose whisker) and cellulose nanofibrils (CNFs, also known as nanofibrillated cellulose or NFCs) which when...

Health Services Management Education On-Site at a Military Medical Center

ERIC Educational Resources Information Center

Williams, Stephen J.; Poss, W. Bradley; Cupp, Craig L.

2014-01-01

A cooperative educational program with the U.S. military is described to illustrate a unique opportunity that confronted a graduate healthcare management program. The resulting degree program supported the military's operational medical mission but also presented interesting and unexpected challenges resulting from the wars in Iraq and…

Creating Opportunities: Good Practice in Small Business Training for Australian Rural Women.

ERIC Educational Resources Information Center

Simpson, Lyn; Daws, Leonie; Wood, Leanne

2002-01-01

To overcome barriers to participation in small business training faced by rural Australian women, training needs and delivery issues were identified and a good practice matrix was developed with the following components: marketing, content, delivery, support, impact, and innovation. Underlying principles included unique needs, diversity, use of…