Sample records for unit subject matter

  1. [Response to US review rules on patent subject matter of traditional Chinese medicine compositions].

    PubMed

    Liu, Pan; Cao, Ya-di; Gong, Rui-Juan; Liu, Wei

    2018-02-01

    The United States Patent and Trademark Office(USPTO) issued Interim Guidance on Patent Subject Matter Eligibility on December 16， 2014， bringing certain effects to the review rules on patent application of Chinese medicine compositions. Based on the Interim Guidance， cases analysis was used in this paper to analyze the patent subject matter issues of traditional Chinese medicine compositions in the United States. The researches have shown that the application documents should be properly written in the United States when the patent for Chinese medicine compositions is applied， which can improve the probability of authorization. Copyright© by the Chinese Pharmaceutical Association.

  2. 19 CFR 103.11 - Specific Customs Service records subject to disclosure.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Department of the Treasury or of the United States Customs Service in matters administered by the United... contained therein is exempt from disclosure under § 103.12; (ii) Advisory committees on Customs matters... 19 Customs Duties 1 2012-04-01 2012-04-01 false Specific Customs Service records subject to...

  3. 19 CFR 103.11 - Specific Customs Service records subject to disclosure.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Department of the Treasury or of the United States Customs Service in matters administered by the United... contained therein is exempt from disclosure under § 103.12; (ii) Advisory committees on Customs matters... 19 Customs Duties 1 2014-04-01 2014-04-01 false Specific Customs Service records subject to...

  4. 19 CFR 103.11 - Specific Customs Service records subject to disclosure.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Department of the Treasury or of the United States Customs Service in matters administered by the United... contained therein is exempt from disclosure under § 103.12; (ii) Advisory committees on Customs matters... 19 Customs Duties 1 2011-04-01 2011-04-01 false Specific Customs Service records subject to...

  5. 19 CFR 103.11 - Specific Customs Service records subject to disclosure.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Department of the Treasury or of the United States Customs Service in matters administered by the United... contained therein is exempt from disclosure under § 103.12; (ii) Advisory committees on Customs matters... 19 Customs Duties 1 2013-04-01 2013-04-01 false Specific Customs Service records subject to...

  6. Documentary Elements in Early Films.

    ERIC Educational Resources Information Center

    Sanderson, Richard A.

    Focusing on documentary elements, this study examines the film content and film techniques of 681 motion pictures produced in the United States prior to 1904. Analysis of films by type, subject matter, and trends in subject matter shows that one-third of the early films are documentary in type and three-fourths of the films use subject matter of a…

  7. Self-Regulated Learning Microanalysis as a Tool to Inform Professional Development Delivery in Real-Time

    ERIC Educational Resources Information Center

    Peters-Burton, Erin E.; Botov, Ivan S.

    2017-01-01

    Elementary teachers in the United States are tasked with teaching all core subject matter and have training that involves many topics, which may limit the depth of their subject matter knowledge. Since they have low content knowledge, they often feel less confident about teaching technical subject matter, such as science (Bleicher "Journal of…

  8. 19 CFR 201.37 - Changing the time, place, subject matter, or determination to open or close a meeting following a...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 3 2011-04-01 2011-04-01 false Changing the time, place, subject matter, or determination to open or close a meeting following a public notice. 201.37 Section 201.37 Customs Duties UNITED... Public Observation Pursuant to 5 U.S.C. 552b § 201.37 Changing the time, place, subject matter, or...

  9. 19 CFR 201.37 - Changing the time, place, subject matter, or determination to open or close a meeting following a...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 3 2012-04-01 2012-04-01 false Changing the time, place, subject matter, or determination to open or close a meeting following a public notice. 201.37 Section 201.37 Customs Duties UNITED... Public Observation Pursuant to 5 U.S.C. 552b § 201.37 Changing the time, place, subject matter, or...

  10. 19 CFR 201.37 - Changing the time, place, subject matter, or determination to open or close a meeting following a...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 3 2013-04-01 2013-04-01 false Changing the time, place, subject matter, or determination to open or close a meeting following a public notice. 201.37 Section 201.37 Customs Duties UNITED... Public Observation Pursuant to 5 U.S.C. 552b § 201.37 Changing the time, place, subject matter, or...

  11. 19 CFR 201.37 - Changing the time, place, subject matter, or determination to open or close a meeting following a...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Changing the time, place, subject matter, or determination to open or close a meeting following a public notice. 201.37 Section 201.37 Customs Duties UNITED... Public Observation Pursuant to 5 U.S.C. 552b § 201.37 Changing the time, place, subject matter, or...

  12. 19 CFR 201.37 - Changing the time, place, subject matter, or determination to open or close a meeting following a...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 3 2014-04-01 2014-04-01 false Changing the time, place, subject matter, or determination to open or close a meeting following a public notice. 201.37 Section 201.37 Customs Duties UNITED... Public Observation Pursuant to 5 U.S.C. 552b § 201.37 Changing the time, place, subject matter, or...

  13. A Portfolio of Energy Ideas: Science.

    ERIC Educational Resources Information Center

    Clark, Richard C., Ed.

    Ten units which focus on subject-matter knowledge about energy and on the logic and strategy of problem-solving within science are provided in this user's guide. Each unit includes: a detailed summary of unit problems and activities; recommended grade levels and subject areas; possible learner outcomes and general goals; teacher background…

  14. 77 FR 269 - Matters Related to Patent Appeals

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-04

    ... DEPARTMENT OF COMMERCE United States Patent and Trademark Office Matters Related to Patent Appeals... Matters Related to Patent Appeals comment'' in the subject line of the message. Mail: Susan K. Fawcett... of opinion on such matters concern the denial of patent claims because of prior art or other...

  15. Middle-School Teachers' Understanding and Teaching of the Engineering Design Process: A Look at Subject Matter and Pedagogical Content Knowledge

    ERIC Educational Resources Information Center

    Hynes, Morgan M.

    2012-01-01

    This paper reports on research investigating six middle school teachers without engineering degrees as they taught an engineering unit on the engineering design process. Videotaped classroom sessions and teacher interviews were analyzed to understand the subject matter and pedagogical content knowledge the teachers used and developed as they…

  16. Dolly and Alice

    PubMed Central

    Burk, Dan L.

    2015-01-01

    The opinion of the United States Court of Appeals for the Federal Circuit, In re Roslin Institute, rejecting patent claims to mammals cloned from somatic cells, was rendered about a month before the United States Supreme Court's decision in Alice Corp. v. CLS Bank International. The Alice opinion explicitly sets out the standard for determining whether an invention falls within statutory patentable subject matter. Thus one is thus left to wonder what the Roslin opinion might have looked like had it been decided only a few weeks later, after the Alice decision was published, with the benefit of the Supreme Court's further direction on patentable subject matter. In this essay I explore whether in hindsight the Alice standard might have dictated a different outcome in Roslin, suggesting how the two-part test articulated by the Supreme Court in Alice might apply to a ‘products of nature’ analysis for cloned mammals. Drawing on that analysis, I then use the Roslin case as a vehicle to highlight certain issues with the Supreme Court's current subject matter jurisprudence as applied to biotechnology. By juxtaposing Dolly with Alice, it becomes clear that the Supreme Court has revivified a number of dormant biotechnology patent problems in the guise of subject matter analysis. PMID:27774214

  17. Patentability of Stem Cells in the United States.

    PubMed

    Fendrick, Sarah E; Zuhn, Donald L

    2015-08-20

    Until recently, the patentability of stem cells was well established within the judicial and statutory framework in the United States. However, the shifting landscape of patent law, particularly with regard to patent-eligible subject matter under 35 U.S.C. §101, presents new challenges to the patentability of stem cells. In this paper, we discuss the legal precedent that paved the way for stem cell patents, including Diamond v. Chakrabarty and In re Bergy. Additionally, we review recent Supreme Court cases and recent guidance issued by the U.S. Patent and Trademark Office that impose new limitations on patent-eligible subject matter and thereby threaten the patentability of stem cells in the United States. Copyright © 2015 Cold Spring Harbor Laboratory Press; all rights reserved.

  18. Ecology of Missouri Forests. Instructional Unit. Conservation Education Series.

    ERIC Educational Resources Information Center

    Jackson, Jim

    This unit is designed to help science, social studies, vocational agriculture, and other teachers incorporate forest ecology concepts into their subject matter. The unit includes: (1) topic outline; (2) unit objectives; (3) background information on climate and soils, levels of a deciduous forest, age classes, food and energy relationships, forest…

  19. 76 FR 40931 - In the Matter of Certain Flash Memory and Products Containing Same; Notice of Commission...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-12

    ... INTERNATIONAL TRADE COMMISSION [Inv. No. 337-TA-685] In the Matter of Certain Flash Memory and... for importation, and the sale within the United States after importation of certain flash memory and... other agreements, written or oral, express or implied, between the parties concerning the subject matter...

  20. Which One Is Better? Jigsaw II versus Jigsaw IV on the Subject of the Building Blocks of Matter and Atom

    ERIC Educational Resources Information Center

    Turkmen, Hakan; Buyukaltay, Didem

    2015-01-01

    In this study, the effect of using Jigsaw II and Jigsaw IV techniques on the subject of "Atoms-The Basic Unit of Matter" in science course of 6th grade on academic achievement was examined. Pre-test post-test control group research was used in the study. Study population is all secondary schools in Turgutlu district of Manisa province…

  1. A Portfolio of Energy Ideas: Science.

    ERIC Educational Resources Information Center

    Clark, Richard C., Ed.

    Presented are 10 science energy education units designed to help students learn how to turn science questions and problems about energy into experiments. Each unit focuses on subject-matter knowledge and on the logic and strategy of scientific problem solving. These teacher-oriented materials include an overview of each unit, background…

  2. Patent first, ask questions later: morality and biotechnology in patent law.

    PubMed

    Bagley, Margo A

    2003-12-01

    This Article explores the U.S. "patent first, ask questions later" approach to determining what subject matter should receive patent protection. Under this approach, the U.S. Patent and Trademark Office (USPTO or the Agency) issues patents on "anything under the sun made by man," and to the extent a patent's subject matter is sufficiently controversial, Congress acts retrospectively in assessing whether patents should issue on such interventions. This practice has important ramifications for morally controversial biotechnology patents specifically, and for American society generally. For many years a judicially created "moral utility" doctrine served as a type of gatekeeper of patent subject matter eligibility. The doctrine allowed both the USTPO and courts to deny patents on morally controversial subject matter under the fiction that such inventions were not "useful." The gate, however, is currently untended. A combination of the demise of the moral utility doctrine, along with expansive judicial interpretations of the scope of patent-eligible subject matter, has resulted in virtually no basis on which the USTPO or courts can deny patent protection to morally controversial, but otherwise patentable, subject matter. This is so despite position statements by the Agency to the contrary. Biotechnology is an area in which many morally controversial inventions are generated. Congress has been in react-mode following the issuance of a stream of morally controversial biotech patents, including patents on transgenic animals, surgical methods, and methods of cloning humans. With no statutory limits on patent eligibility, and with myriad concerns complicating congressional action following a patent's issuance, it is not Congress, the representative of the people, determining patent eligibility. Instead, it is patent applicants, scientific inventors, who are deciding matters of high public policy through the contents of the applications they file with the USTPO. This Article explores how the United States has come to be in this position, exposes latent problems with the "patent first" approach, and considers the benefits and disadvantages of the "ask questions first, patents later" approaches employed by some other countries. The Article concludes that granting patents on morally controversial biotech subject matter and then asking whether such inventions should be patentable is bad policy for the United States and its patent system, and posits workable, proactive ways for Congress to successfully guard the patent-eligibility gate.

  3. 10 CFR 14.57 - Suit against United States exclusive remedy.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Suit against United States exclusive remedy. 14.57 Section... Employee Drivers § 14.57 Suit against United States exclusive remedy. The remedy against the United States... of the same subject matter against the employee or his or her estate whose act or omission gave rise...

  4. 10 CFR 14.57 - Suit against United States exclusive remedy.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Suit against United States exclusive remedy. 14.57 Section... Employee Drivers § 14.57 Suit against United States exclusive remedy. The remedy against the United States... of the same subject matter against the employee or his or her estate whose act or omission gave rise...

  5. Update on Graduation Rate Reporting: Issues and Opportunities. Policy Matters: A Higher Education Policy Brief

    ERIC Educational Resources Information Center

    Russell, Alene

    2009-01-01

    Since the passage of the federal Student Right-to-Know Act of 1990 (SRTK), graduation rates have been a subject of much debate and controversy. Why all the fuss? The simple truth is that graduation from college does matter, and it matters more than ever. From the societal perspective, the United States is falling behind other nations in the…

  6. Modern Problems: Sociology Units. An Experimental Program for Grade 12.

    ERIC Educational Resources Information Center

    Carlson, Marshall; Fennig, Lois

    GRADES OR AGES: Grade 12. SUBJECT MATTER: Sociology; modern problems. ORGANIZATION AND PHYSICAL APPEARANCE: The guide contains two units, one on the problems of minority groups and the other on social pathology. Sub-sections of unit 2 include crime and criminals, criminal investigation, gun control, U.S. criminal law, criminal procedure,…

  7. Social Studies for EMR Pupils: A Course of Study for Senior High Schools.

    ERIC Educational Resources Information Center

    Casler, Al; And Others

    Presented are 10 units of study for educable mentally retarded (EMR) senior high school students in the area of social studies. The outlined sequence and suggested time allotment for each unit covers grades 10-12. Subject matter content of each unit is outlined in detail; particular teaching methods and materials are not specified. Units cover the…

  8. Between Inflation and Recession: A Literacy Unit on the American Economic System.

    ERIC Educational Resources Information Center

    Lawrence, Sharon; And Others

    This four-week unit on the American economic system for secondary students is intended to be a basic literacy unit in economics and to serve as a "sampler kit" demonstrating how economics can be taught interestingly, imaginatively, and with intellectual honesty to the subject matter. The unit's goals for students include ability to list the major…

  9. [Secondary Career Education Activities: Social Studies.

    ERIC Educational Resources Information Center

    Radford City Schools, VA.

    The guide is one of a series developed in a pilot project to integrate career education concepts with subject matter in secondary grades. The units are designed to reveal career orientation aspects of traditional topics within five major subject areas: English, social studies, mathematics, science, and health and physical education. The lesson…

  10. [Secondary Career Education Activities: Science.

    ERIC Educational Resources Information Center

    Radford City Schools, VA.

    The guide is one of a series developed in a pilot project to integrate career education concepts with subject matter in secondary grades. The units are designed to reveal career orientation aspects of traditional topics within five major subject areas: English, social studies, mathematics, science, and health and physical education. The lesson…

  11. 22 CFR 304.12 - Action on approved claim.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... an award, compromise, or settlement made under section 2672 or 2677 of title 28, United States Code... any claim against the United States and against any officer or employee of the Government whose act or omission gave rise to the claim, by reason of the same subject matter. ...

  12. General Mechanical Trades: A Curriculum Guide. Revised Edition.

    ERIC Educational Resources Information Center

    Henderson, W. Charles; And Others

    The guide contains six sections, each consisting of one or more units of general mechanical trades instruction. The sections cover: safety and tools, measuring and blueprint reading, gas welding, arc welding, small engines, and metal work. Each unit includes performance objectives stated as terminal objectives, indicating the subject matter to be…

  13. Science Experience Unit: Plant and Animal Adaptations.

    ERIC Educational Resources Information Center

    Ferguson-Florissant School District, Ferguson, MO.

    GRADES OR AGES: No mention. Appears to be upper elementary. SUBJECT MATTER: Science units--plants and animals. ORGANIZATION AND PHYSICAL APPEARANCE: The guide is divided into 35 activities. It is mimeographed and staple-bound with a paper cover. OBJECTIVES AND ACTIVITIES: No objectives are mentioned. The activities suggested aim to recreate common…

  14. [Secondary Career Education Activities: Health and Physical Education.

    ERIC Educational Resources Information Center

    Radford City Schools, VA.

    The guide is one of a series developed in a pilot project to integrate career education concepts with subject matter in secondary grades. The units are designed to reveal career orientation aspects of traditional topics within five major subject areas: English, social studies, mathematics, science, and health and physical education. The lesson…

  15. 78 FR 765 - Large Residential Washers From Korea and Mexico; Revised Schedule for the Subject Investigations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-04

    ... INTERNATIONAL TRADE COMMISSION [Investigation Nos. 701-TA-488 and 731-TA-1199-1200 (Final)] Large Residential Washers From Korea and Mexico; Revised Schedule for the Subject Investigations AGENCY: United... information on this matter by contacting the Commission's TDD terminal on 202-205-1810. Persons with mobility...

  16. [Elementary Career Education Units: Grade 1.

    ERIC Educational Resources Information Center

    Radford City Schools, VA.

    The guide is one of a series developed in a pilot project to integrate career education concepts with traditional subject matter and topics in elementary grades K-7 and in special education. Developed by teachers in the Radford, Virginia, schools, the units make use of resource persons from outside the school, occupational information,…

  17. Music. Grade 13. Curriculum S.16.

    ERIC Educational Resources Information Center

    Ontario Dept. of Education, Toronto.

    GRADES OR AGES: Grade 13. SUBJECT MATTER: Music. ORGANIZATION AND PHYSICAL APPEARANCE: The central portion of the guide is divided into six units: voice, strings, woodwinds, brass, percussion, and theory and form. Each unit is in list form. The guide is offset printed and staple-bound with a paper cover. OBJECTIVES AND ACTIVITIES: A list of…

  18. Course Development. A Manual for Editors of Distance-Teaching Materials.

    ERIC Educational Resources Information Center

    Jenkins, Janet

    This manual is intended to train distance education staff in how to develop and edit teaching materials. Addressed in the individual units of the guide are the following topics: appointing writers, preparing to write, developing a course outline, selecting the structure of a unit, presenting the subject matter, developing student activities,…

  19. AUTOMOTIVE DIESEL MAINTENANCE 2. UNIT I, UNDERSTANDING MECHANICAL CLUTCHES.

    ERIC Educational Resources Information Center

    Minnesota State Dept. of Education, St. Paul. Div. of Vocational and Technical Education.

    ONE OF A 25-MODULE COURSE DESIGNED TO UPGRADE THE JOB SKILLS AND TECHNICAL KNOWLEDGE OF DIESEL MAINENANCE MECHANICS THIS MATERIAL WAS DEVELOPED BY INDUSTRIAL TRAINING AND SUBJECT-MATTER SPECIALISTS AND TESTED IN INDUSTRIAL TRAINING SITUATIONS. THE PURPOSE OF THIS FIRST UNIT IS TO DEVELOP AN UNDERSTANDING OF COMPONENTS, OPERATION, AND ADJUSTMENTS…

  20. [Elementary Career Education Units: Grades 6 and 7.

    ERIC Educational Resources Information Center

    Radford City Schools, VA.

    The guide is one of a series developed in a pilot project to integrate career education concepts with traditional subject matter and topics in elementary grades K-7 and in special education. Developed by teachers in the Radford, Virginia, schools, the units make use of resource persons from outside the school, occupational information,…

  1. International Workforce Development Perspectives: Germany and the United States

    ERIC Educational Resources Information Center

    Gaal, John

    2007-01-01

    Across the globe, it is no secret to people involved with career and technical education (CTE) that the German apprenticeship system is looked upon as the "gold standard" of workforce development training. In this article, the author compares the responses of subject matter experts (SMEs) in Germany and the United States, two of the…

  2. Biology 23. Unit One -- The Cell: Structure and Physiology.

    ERIC Educational Resources Information Center

    Nederland Independent School District, TX.

    GRADES OR AGES: Not given. SUBJECT MATTER: Biology, the structure and physiology of the cell. ORGANIZATION AND PHYSICAL APPEARANCE: There are four sections: a) objectives for the unit, b) bibliography, c) activities, and d) evaluation. The guide is directed to the student rather than the teacher. The guide is mimeographed and stapled, with no…

  3. [Elementary Career Education Units: Grade 2.

    ERIC Educational Resources Information Center

    Radford City Schools, VA.

    The guide is one of a series developed in a pilot project to integrate career education concepts with traditional subject matter and topics in elementary grades K-7 and in special education. Developed by teachers in the Radford, Virginia, schools, the units make use of resource persons from outside the school, occupational information,…

  4. 45 CFR 35.8 - Release.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... constitute a complete release of any claim against the United States and against any employee of the Government whose act or omission gave rise to the claim, by reason of the same subject matter. ...

  5. Getting Down to Business: Tree Service, Module 3. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Shapiro, Norma

    This module on owning and operating a tree service is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit activity. Units (and subject matter) in this module…

  6. Transforming Effective Army Units: Best Practices and Lessons Learned

    DTIC Science & Technology

    2013-08-01

    Unlimited 106 Dorothy Young 703-545-2316 ii iii Technical Report 1326 Effective Army Units: Best Practices and Lessons Learned...SBCT units at Joint Base Lewis -McChord (JBLM), and two civilian subject matter experts on transformation from the Program Manager (PM) Stryker and...ISR Intelligence, Surveillance, Reconnaissance JBLM Joint Base Lewis -McChord JRTC Joint Readiness Training Center A-2 LNO Liaison

  7. 14 CFR 1261.312 - Action on approved claims.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... constitute a complete release of any claim against the United States and against any employee of the Government whose act or omission gave rise to the claim, by reason of the same subject matter. ...

  8. AUTOMOTIVE DIESEL MAINTENANCE 1. UNIT I, GENERAL INTRODUCTION TO DIESEL ENGINES.

    ERIC Educational Resources Information Center

    Human Engineering Inst., Cleveland, OH.

    ONE OF A 30-MODULE COURSE DESIGNED TO UPGRADE THE JOB SKILLS AND TECHNICAL KNOWLEDGE OF DIESEL MAINTENANCE MECHANICS, THIS MATERIAL WAS DEVELOPED BY INDUSTRIAL TRAINING AND SUBJECT-MATTER SPECIALISTS AND TESTED IN INDUSTRIAL TRAINING SITUATIONS. THE PURPOSE OF THIS FIRST UNIT IS TO PROVIDE AN INTRODUCTION TO DIESEL ENGINES BY DEVELOPING AN…

  9. THE IMPACT OF CHANGING SCIENTIFIC KNOWLEDGE ON SCIENCE EDUCATION IN THE UNITED STATES SINCE 1850.

    ERIC Educational Resources Information Center

    DEL GIORNO, BETTE JOYCE

    ANALYZED WAS THE IMPACT OF CHANGING SCIENTIFIC KNOWLEDGE ON SCIENCE EDUCATION IN THE UNITED STATES FROM 1850 THROUGH 1954. THE OBJECTIVES WERE TO IDENTIFY (1) MAJOR DEVELOPMENTS IN SCIENCE, (2) IMPORTANT EVENTS IN EDUCATION, (3) THE PHILOSOPHICAL AND PSYCHOLOGICAL CLIMATE, (4) THE SCIENCE CURRICULUM AND SUBJECT MATTER, AND (5) THE APPROACH TO…

  10. A Guide to Concept Teaching, United States History, Grade 9. (From Reconstruction to the Present).

    ERIC Educational Resources Information Center

    Madison Public Schools, WI.

    GRADES OR AGES: Grade 9. SUBJECT MATTER: United States history. ORGANIZATION AND PHYSICAL APPEARANCE: The conceptual approach forms the basis for each of four sections: Defining and Implementing a Conceptual Approach to Teaching Social Studies; Social Studies Skills To Be Developed and Reinforced by the Learner; Classroom Curriculum Planning; and…

  11. Man and the Environment. A Bibliography of Selected Publications of the United Nations System 1946-1971.

    ERIC Educational Resources Information Center

    Winton, Harry N. M., Comp.

    Publication of the international agencies of the United Nations system, thru 1971, that refer to man, world natural resources, the environment and population trends are arranged according to subject matter. Within most categories, entries are arranged by geographical area. Descriptive annotations are provided for each of the more than 1200…

  12. Electromagnetism Unit of an Introductory University Physics Course: The Influence of a Reform-Based Tutorial

    ERIC Educational Resources Information Center

    Barrett, Sarah Elizabeth; Hazari, Zahra; Fatholahzadeh, Baharak; Harrison, David M.

    2012-01-01

    Many students enrolled in university physics have little interest in the subject matter, a trend more pronounced in females. This study assesses students' conceptual understanding and interest during the electrochemistry unit of a physics course for nonphysics majors that was revised in light of consistently low ratings from its students. The…

  13. Siddartha: An Introduction to Buddhism and Hinduism Yesterday and Today.

    ERIC Educational Resources Information Center

    Mooney, Edward L.

    This three-week unit in world literature for 11th grade, average-ability students was developed as part of a series by the Public Education Religion Studies Center at Wright State University. An outline of the unit's content and subject matter is given. The novel "Siddhartha" is studied in its Hindu and Buddhist religious and cultural…

  14. Getting Down to Business: Plumbing Business, Module 35. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Sanderson, Barbara

    This module on owning and operating a plumbing business is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are divided…

  15. Getting Down to Business: Guard Service, Module 27. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Colby, Pamela G.

    This module on owning and operating a guard service is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are divided into…

  16. Getting Down to Business: Welding Business, Module 32. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Gall, Joyce P.

    This module on owning and operating a welding business is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are divided…

  17. Getting Down to Business: Bicycle Store, Module 10. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Sanderson, Barbara

    This module on owning and operating a bicycle store is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are divided into…

  18. Getting Down to Business: Pest Control Service, Module 28. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Colby, Pamela G.

    This module on owning and operating a pest control service is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are…

  19. Getting Down to Business: Answering Service, Module 17. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Shapiro, Norma

    This module on owning and operating an answering service is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are divided…

  20. Getting Down to Business: Construction Electrician Business, Module 33. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Gall, Joyce P.

    This module on owning and operating a construction electrician business is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning…

  1. Getting Down to Business: Bookkeeping Service, Module 19. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Shapiro, Norma

    This module on owning and operating a bookkeeping service is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are…

  2. Getting Down to Business: Housecleaning Service, Module 24. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    McFarlane, Carolyn

    This module on owning and operating a housecleaning service is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are…

  3. Getting Down to Business: Specialty Food Store, Module 8. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Rassen, Rachel L.

    This module on owning and operating a specialty food store is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are…

  4. Getting Down to Business: Word Processing Service, Module 21. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Shapiro, Norma

    This module on owning and operating a word processing service is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are…

  5. Getting Down to Business: Farm Equipment Repair, Module 2. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    McBain, Susan

    This module on owning and operating a farm equipment repair business is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning…

  6. Getting Down to Business: Home Attendant Service, Module 26. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Sanderson, Barbara

    This module on owning and operating a home attendant service is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are…

  7. Getting Down to Business: Fertilizer and Pesticide Service, Module 5. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    McBain, Susan L.

    This module on owning and operating a fertilizer and pesticide service is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning…

  8. Getting Down to Business: Garden Center, Module 4. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    McBain, Susan L.

    This module on owning and operating a garden center is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are divided into…

  9. Getting Down to Business: Software Design Company, Module 20. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Shapiro, Norma

    This module on owning and operating a software design company is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are…

  10. Getting Down to Business: Carpentry Business, Module 34. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Gall, Joyce P.

    This module on owning and operating a carpentry business is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are divided…

  11. Getting Down to Business: Sewing Service, Module 25. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Kingi, Marcella

    This module on owning and operating a sewing service is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are divided…

  12. Getting Down to Business: Restaurant Business, Module 22. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Kingi, Marcella

    This module on owning and operating a restaurant is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are divided into…

  13. Getting Down to Business: Energy Specialist Service, Module 29. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Colby, Pamela G.

    This module on owning and operating an energy specialist service is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are…

  14. Getting Down to Business: Wheelchair Transportation Service, Module 15. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Wolman, Jean

    This module on owning and operating a wheelchair transportation service is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning…

  15. Getting Down to Business: Health Spa, Module 16. [Student Module]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Wolman, Jean

    This module on owning and operating a health spa is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are divided into…

  16. Getting Down to Business: Secretarial Service, Module 18. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Shapiro, Norma

    This module on owning and operating a secretarial service is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are…

  17. Getting Down to Business: Nursing Service, Module 14. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Wolman, Jean

    This module on owning and operating a nursing service is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are divided…

  18. Getting Down to Business: Dairy Farming, Module 6. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    McBain, Susan L.

    This module on owning and operating a dairy farm is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are divided into…

  19. Getting Down to Business: Apparel Store, Module 7. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Rassen, Rachel L.

    This module on owning and operating an apparel store is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are divided…

  20. Getting Down to Business: Innkeeping, Module 13. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Rassen, Rachel L.

    This module on owning and operating an inn is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are divided into…

  1. Resource Handbook--Space Beyond the Earth. A Supplement to Basic Curriculum Guide--Science, Grades K-6.

    ERIC Educational Resources Information Center

    Starr, John W., 3rd., Ed.

    GRADES OR AGES: Grades K-6. SUBJECT MATTER: Science; space. ORGANIZATION AND PHYSICAL APPEARANCE: The guide is divided into four units: 1) the sun, earth, and moon; 2) stars and planets; 3) exploring space; 4) man's existence in space. Each unit includes initiatory and developmental activities. There are also sections on evaluation, vocabulary,…

  2. Getting Down to Business: Travel Agency, Module 9. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Rassen, Rachel L.

    This module on owning and operating a travel agency is one of 36 modules in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are…

  3. Characterization of a CMOS sensing core for ultra-miniature wireless implantable temperature sensors with application to cryomedicine.

    PubMed

    Khairi, Ahmad; Thaokar, Chandrajit; Fedder, Gary; Paramesh, Jeyanandh; Rabin, Yoed

    2014-09-01

    In effort to improve thermal control in minimally invasive cryosurgery, the concept of a miniature, wireless, implantable sensing unit has been developed recently. The sensing unit integrates a wireless power delivery mechanism, wireless communication means, and a sensing core-the subject matter of the current study. The current study presents a CMOS ultra-miniature PTAT temperature sensing core and focuses on design principles, fabrication of a proof-of-concept, and characterization in a cryogenic environment. For this purpose, a 100 μm × 400 μm sensing core prototype has been fabricated using a 130 nm CMOS process. The senor has shown to operate between -180°C and room temperature, to consume power of less than 1 μW, and to have an uncertainty range of 1.4°C and non-linearity of 1.1%. Results of this study suggest that the sensing core is ready to be integrated in the sensing unit, where system integration is the subject matter of a parallel effort. Copyright © 2014 IPEM. Published by Elsevier Ltd. All rights reserved.

  4. One Subject, Two Lands: My Journey in Condensed Matter Physics

    NASA Astrophysics Data System (ADS)

    Ramakrishnan, T. V.

    2016-03-01

    This is an account of a professional life in the field that was generally known as solid-state physics when I started working in it; India and the United States of America are the countries in which this life was largely played out. My attempts to understand various things in condensed matter physics, and efforts to put together people and activities in India in this field, are mainly the story.

  5. The Effect of the 4MAT Learning Model on the Achievement and Motivation of 7th Grade Students on the Subject of Particulate Nature of Matter and an Examination of Student Opinions on the Model

    ERIC Educational Resources Information Center

    Aktas, Idris; Bilgin, Ibrahim

    2015-01-01

    Background: Many researchers agree that students, especially primary students, have learning difficulties on the "Particulate Nature of Matter" unit. One reason for this difficulty is not considering individual differences for teaching science. In 4MAT model learning, environment is arranged according to individual differences. Purpose:…

  6. 19 CFR 207.65 - Prehearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 3 2011-04-01 2011-04-01 false Prehearing briefs. 207.65 Section 207.65 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS OF... and arguments which the party believes relevant to the subject matter of the Commission's...

  7. 19 CFR 207.65 - Prehearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Prehearing briefs. 207.65 Section 207.65 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS OF... and arguments which the party believes relevant to the subject matter of the Commission's...

  8. Age, Cumulative Trauma and Stressful Life Events, and Post-Traumatic Stress Symptoms among Older Adults in Prison: Do Subjective Impressions Matter?

    ERIC Educational Resources Information Center

    Maschi, Tina; Morgen, Keith; Zgoba, Kristen; Courtney, Deborah; Ristow, Jennifer

    2011-01-01

    Background: The aging prison population in the United States presents a significant public health challenge with high rates of trauma and mental health issues that the correctional system alone is ill-prepared to address. The purpose of this study was to examine the relationship of age, objective, and subjective measures of trauma and stressful…

  9. Getting Down to Business: Flower and Plant Store, Module 11. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Rassen, Rachel L.

    This module on owning and operating a flower and plant store is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are…

  10. Getting Down to Business: Air Conditioning and Heating Service, Module 36. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Sanderson, Barbara

    This module on owning and operating an air conditioning and heating service is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning…

  11. Getting Down to Business: Business and Personal Service, Module 12. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Rassen, Rachel L.

    This module on owning and operating a business and personal service is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities…

  12. Getting Down to Business: Auto Body Shop, Module 31. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    McFarlane, Carolyn

    This module on owning and operating an auto repair shop is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are divided…

  13. Getting Down to Business: Day Care Center, Module 23. [Student Manual]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Kingi, Marcella

    This module on owning and operating a day care center is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are divided…

  14. LAW ENFORCEMENT OFFICER TRAINING, BASIC COURSE, UNIT II, A UNIT OF THE OHIO LAW ENFORCEMENT OFFICERS' TRAINING PROGRAM, LEARNER'S MANUAL.

    ERIC Educational Resources Information Center

    REESE, ROBERT M.; AND OTHERS

    STUDENTS MAY USE THIS MANUAL IN A LAW ENFORCEMENT TRAINING PROGRAM FOR INSERVICE LAW ENFORCEMENT OFFICERS AND RECRUITS. IT WAS DEVELOPED BY A STATEWIDE COMMITTEE OF LAW ENFORCEMENT TRAINING CONSULTANTS, SPECIALISTS, AND AN ADVISORY COMMITTEE AND WAS TESTED BY A SUBJECT MATTER SPECIALIST IN A PILOT-CLASS STUDY. THE PROGRAM IS DESIGNED TO PROVIDE…

  15. Getting Down to Business: Hair Styling Shop, Module 30. [Student Guide]. Entrepreneurship Training Components.

    ERIC Educational Resources Information Center

    Gall, Joyce P.

    This module on owning and operating a hair styling shop is one of 36 in a series on entrepreneurship. The introduction tells the student what topics will be covered and suggests other modules to read in related occupations. Each unit includes student goals, a case study, and a discussion of the unit subject matter. Learning activities are divided…

  16. A Private [School] Matter: The State of Materials Challenges in Private College Preparatory School Libraries in the Southeast United States

    ERIC Educational Resources Information Center

    Franklin, Renee E.

    2008-01-01

    Materials challenges and censorship occur often in public and private educational settings. Private schools and their library media centers are not subject to the First Amendment but research reported in this article examines the state of challenges to materials held in private schools media centers in the southeast United States as a way to gauge…

  17. 19 CFR 207.23 - Prehearing brief.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 3 2013-04-01 2013-04-01 false Prehearing brief. 207.23 Section 207.23 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS OF... include information and arguments which the party believes relevant to the subject matter of the...

  18. 19 CFR 207.23 - Prehearing brief.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 3 2014-04-01 2014-04-01 false Prehearing brief. 207.23 Section 207.23 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS OF... include information and arguments which the party believes relevant to the subject matter of the...

  19. 19 CFR 207.65 - Prehearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 3 2014-04-01 2014-04-01 false Prehearing briefs. 207.65 Section 207.65 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS OF... believes relevant to the subject matter of the Commission's determination. [76 FR 61944, Oct. 6, 2011] ...

  20. Sociology.

    ERIC Educational Resources Information Center

    Bensalam Township School District, Cornwells Heights, PA.

    GRADES OR AGES: High school (grades not specified). SUBJECT MATTER: Sociology. ORGANIZATION AND PHYSICAL APPEARANCE: The course contains 13 units. The material is set out in columns--content, student activities, time, teacher activity or strategy, materials, and evaluation. The guide is mimeographed and spiral bound with a soft cover. OBJECTIVES…

  1. Psychology.

    ERIC Educational Resources Information Center

    Bensalam Township School District, Cornwells Heights, PA.

    GRADES OR AGES: High school (grades not specified). SUBJECT MATTER: Psychology. ORGANIZATION AND PHYSICAL APPEARANCE: The course contains 12 units. The material is set out in columns--content, student activities, time, teacher activity or strategy, materials, and evaluation. The guide is mimeographed and spiral bound with a soft cover. OBJECTIVES…

  2. 20 CFR 429.108 - What happens if I accept an award, compromise, or settlement under this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... constitutes a complete release of any claim against the United States and against any employee of the Government whose act or omission gave rise to the claim, by reason of the same subject matter. ...

  3. 20 CFR 429.108 - What happens if I accept an award, compromise, or settlement under this subpart?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... constitutes a complete release of any claim against the United States and against any employee of the Government whose act or omission gave rise to the claim, by reason of the same subject matter. ...

  4. FPI Cohort Reports: Canada/CAUBO

    ERIC Educational Resources Information Center

    Dew, George

    2013-01-01

    CAUBO--the Canadian Association of University Business Officers--is a volunteer-driven organization that represents the administrative function of virtually all Canadian universities (CAUBO is the Canadian counterpart to NACUBO in the United States). Member committees provide direction and subject matter expertise, with each committee typically…

  5. 75 FR 78732 - In the Matter of Certain Caskets; Notice of Commission Issuance of a Limited Exclusion Order...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-16

    ... exclusion order against infringing products of Ataudes Aguilares, S. de R.L. de C.V. of Guadalajara, Mexico... subject articles. The Commission's order was delivered to the President and the United States Trade...

  6. Reforming English Curriculum in United Arab Emirates: An Examination of Emirate Teachers' Beliefs and Practices Regarding the Adoption of "English Continous Assessment Rich Task" (ECART)

    ERIC Educational Resources Information Center

    AlAlili, Sara

    2014-01-01

    United Arab Emirates (UAE) is currently undergoing massive educational reform, especially in the teaching and assessment methods of all subject-matter areas. In Abu Dhabi, the capital of UAE, the Abu Dhabi Education Council (ADEC) has mandated the revamping of English language teaching and assessment in grades 6-12 through the introduction of…

  7. 48 CFR 27.203-1 - General.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... contractor how to transmit the application to the United States Patent Office in accordance with procedures... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patents and Copyrights 27.203-1 General. (a) Unauthorized disclosure of classified subject matter, whether in patent applications or resulting from the issuance of a...

  8. 37 CFR 1.9 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE... the subject matter of a joint invention. (e) The term joint research agreement as used in this chapter... entities for the performance of experimental, developmental, or research work in the field of the claimed...

  9. 37 CFR 1.9 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE... the subject matter of a joint invention. (e) The term joint research agreement as used in this chapter... entities for the performance of experimental, developmental, or research work in the field of the claimed...

  10. 48 CFR 27.203-1 - General.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... contractor how to transmit the application to the United States Patent Office in accordance with procedures... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patents and Copyrights 27.203-1 General. (a) Unauthorized disclosure of classified subject matter, whether in patent applications or resulting from the issuance of a...

  11. 48 CFR 27.203-1 - General.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... contractor how to transmit the application to the United States Patent Office in accordance with procedures... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patents and Copyrights 27.203-1 General. (a) Unauthorized disclosure of classified subject matter, whether in patent applications or resulting from the issuance of a...

  12. 48 CFR 27.203-1 - General.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... contractor how to transmit the application to the United States Patent Office in accordance with procedures... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patents and Copyrights 27.203-1 General. (a) Unauthorized disclosure of classified subject matter, whether in patent applications or resulting from the issuance of a...

  13. Physical Education. Secondary

    ERIC Educational Resources Information Center

    Molosky, Gerald; And Others

    GRADES OR AGES: Grades 7-10. SUBJECT MATTER: Physical education. ORGANIZATION AND PHYSICAL APPEARANCE: The guide is divided into six color-coded units, one each for athletic skills and games, fitness testing and body mechanics, rhythmical activities, simple games and recreational activities, tumbling and apparatus, and swimming. It is mimeographed…

  14. Cognitive Requirements for Small Unit Leaders in Military Operations in Urban Terrain

    DTIC Science & Technology

    1998-09-01

    operations specifically. A cognitive task analysis , based on in depth interviews with subject matter experts (n=7), was conducted to expose the...process. The findings of the cognitive task analysis guided the development of training recommendations, particularly the need for a scenario based

  15. GREENHOUSE WORKER, TEACHERS COPY.

    ERIC Educational Resources Information Center

    FITTS, JAMES; JOHNSON, JOHNNY

    DESIGNED FOR VOCATIONAL AGRICULTURE STUDENTS IN A COOPERATIVE PART-TIME TRAINING PROGRAM, THIS GUIDE WAS DEVELOPED BY TWO VOCATIONAL AGRICULTURE TEACHERS WITH INTEREST, TRAINING, AND EXPERIENCE IN HORTICULTURE AND WAS COORDINATED AND EDITED BY A SUBJECT MATTER SPECIALIST. INCLUDED ARE TEN UNITS, EACH DIVIDED INTO TOPICS. EACH TOPIC INCLUDES A…

  16. NURSERY WORKER, TEACHERS COPY.

    ERIC Educational Resources Information Center

    FITTS, JAMES; JOHNSON, JOHNNY

    THE PURPOSE OF THIS GUIDE IS TO ASSIST IN THE PREPARATION OF VOCATIONAL AGRICULTURE COOPERATIVE EDUCATION STUDENTS OVER 16 YEARS OF AGE AS NURSERY WORKERS. IT WAS DEVELOPED BY A COMMITTEE OF VOCATIONAL AGRICULTURE TEACHERS WITH ASSISTANCE FROM SUBJECT MATTER SPECIALISTS. UNITS ARE (1) INTRODUCTION TO HORTICULTURE, (2) CONSTRUCTING, MAINTAINING,…

  17. Content Selection in Advanced Courses

    ERIC Educational Resources Information Center

    Parker, Walter C.; Lo, Jane C.

    2016-01-01

    Advanced high-school courses, such as Advanced Placement (AP) courses in the United States, present a content selection conundrum of major proportions. Judicious content selection is necessary if students are to learn subject matter meaningfully, but the sheer breadth of tested material in these courses promotes nearly the opposite:…

  18. 32 CFR 1801.2 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) days may be added if responding by international mail; Control means ownership or the authority of... judicial branches of government, United States or foreign, or U.S. Government contractor who, in the sole discretion of NACIC, has a subject matter or physical interest in the documents or information at issue...

  19. 32 CFR 1801.2 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) days may be added if responding by international mail; Control means ownership or the authority of... judicial branches of government, United States or foreign, or U.S. Government contractor who, in the sole discretion of NACIC, has a subject matter or physical interest in the documents or information at issue...

  20. 32 CFR 1801.2 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) days may be added if responding by international mail; Control means ownership or the authority of... judicial branches of government, United States or foreign, or U.S. Government contractor who, in the sole discretion of NACIC, has a subject matter or physical interest in the documents or information at issue...

  1. 32 CFR 1801.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) days may be added if responding by international mail; Control means ownership or the authority of... judicial branches of government, United States or foreign, or U.S. Government contractor who, in the sole discretion of NACIC, has a subject matter or physical interest in the documents or information at issue...

  2. Seventh Grade Interdisciplinary Packet (Science-Social Studies).

    ERIC Educational Resources Information Center

    Madison Public Schools, WI. Dept. of Curriculum Development.

    GRADES OR AGES: Grade 7. SUBJECT MATTER: Science and Social Studies. ORGANIZATION AND PHYSICAL APPEARANCE: This guide presents a series of earth sciences units which would have interdisciplinary potential specifically in the area of social studies. Introductory material includes a rationale, evaluation procedures, 44 "key" environmental concepts,…

  3. Science Experience Unit: Conservation.

    ERIC Educational Resources Information Center

    Ferguson-Florissant School District, Ferguson, MO.

    GRADES OR AGES: Intermediate grades. SUBJECT MATTER: Conservation. ORGANIZATION AND PHYSICAL APPEARANCE: The guide is divided into 24 experiments. It is mimeographed and staple-bound with a paper cover. OBJECTIVES AND ACTIVITIES: A specific skill or knowledge objective is stated at the beginning of each experiment. Detailed procedures are listed…

  4. Basic Principles of Animal Science. Reprinted.

    ERIC Educational Resources Information Center

    Florida State Dept. of Education, Tallahassee.

    The reference book is designed to fulfill the need for organized subject matter dealing with basic principles of animal science to be incorporated into the high school agriculture curriculum. The material presented is scientific knowledge basic to livestock production. Five units contain specific information on the following topics: anatomy and…

  5. 19 CFR 201.10 - Public notices.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 3 2011-04-01 2011-04-01 false Public notices. 201.10 Section 201.10 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF GENERAL APPLICATION Initiation and... of producers and importers, and others known to have an interest in the subject matter. [63 FR 29347...

  6. 19 CFR 201.10 - Public notices.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Public notices. 201.10 Section 201.10 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF GENERAL APPLICATION Initiation and... of producers and importers, and others known to have an interest in the subject matter. [63 FR 29347...

  7. 19 CFR 201.10 - Public notices.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 3 2012-04-01 2012-04-01 false Public notices. 201.10 Section 201.10 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF GENERAL APPLICATION Initiation and... of producers and importers, and others known to have an interest in the subject matter. [63 FR 29347...

  8. Basic Curriculum Guide--Science. Grades K-6.

    ERIC Educational Resources Information Center

    Starr, John W., 3rd., Ed.

    GRADES OR AGES: K-6. SUBJECT MATTER: Science. ORGANIZATION AND PHYSICAL APPEARANCE: The guide is in two parts--the background, philosophy, and instructional principles of science teaching, including a resource unit model, and the development by grade level of the various basic scientific concepts. The guide also includes information of…

  9. Physical Science-Supplement: Project Oriented.

    ERIC Educational Resources Information Center

    Nederland Independent School District, TX.

    GRADES OR AGES: No mention; appears to be for secondary grades. SUBJECT MATTER: Physical sciences for slow learners. ORGANIZATION AND PHYSICAL APPEARANCE: The guide is divided into 11 units, each of which is further subdivided into several chapters. Each chapter is laid out in three columns; column headings are concepts, content, and activities.…

  10. 22 CFR 401.20 - Interested persons and counsel.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Interested persons and counsel. 401.20 Section 401.20 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.20 Interested persons and counsel. Governments and persons interested in the subject matter...

  11. 76 FR 47597 - Indian Alcohol and Substance Abuse Memorandum of Agreement Between U.S. Department of Health and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-05

    ... solicit the comments of'' American Indian and Alaska Native individuals, organizations, tribes, and... Board, the National Congress of American Indians, the National Council of Urban Indian Health, and the... organizations, United States Attorneys serving multiple jurisdictions, and Federal subject matter experts...

  12. Characteristics of Resources Represented in the OCLC CORC Database.

    ERIC Educational Resources Information Center

    Connell, Tschera Harkness; Prabha, Chandra

    2002-01-01

    Examines the characteristics of Web resources in Online Computer Library Center's (OCLC) Cooperative Online Resource Catalog (CORC) in terms of subject matter, source of content, publication patterns, and units of information chosen for representation in the database. Suggests that the ability to successfully use a database depends on…

  13. 40 CFR 62.15250 - May I conduct stack testing less often?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... pollutants subject to stack testing requirements: dioxins/furans, cadmium, lead, mercury, particulate matter, opacity, hydrogen chloride, and fugitive ash. (b) You can test less often for dioxins/furans emissions if... municipal waste combustion units have demonstrated levels of dioxins/furans emissions less than or equal to...

  14. Living Effectively in the 70's.

    ERIC Educational Resources Information Center

    Alexis I. DuPont School District, Greenville, DE.

    GRADES OR AGES: Unspecified. SUBJECT MATTER: Effective living. ORGANIZATION AND PHYSICAL APPEARANCE: Most of the pages are divided into three columns: concept, some activities, and teacher comments. The guide is offset printed and spiral bound with a soft cover. OBJECTIVES AND ACTIVITIES: The guide is divided into eight units: human growth and…

  15. Veterinary Assistant, Teachers Copy.

    ERIC Educational Resources Information Center

    Texas A and M Univ., College Station.

    This study guide was developed for use by male and female vocational agriculture cooperative education students, 16 to 20 years old, preparing to become veterinary assistants. It was designed by subject-matter specialists on the basis of state advisory committee recommendations and refined after being tested in operational programs. Units, to be…

  16. E.QUALITY@BT...

    ERIC Educational Resources Information Center

    Macmillan, Roderick H.

    1996-01-01

    Describes a management system developed by BT Laboratories (United Kingdom) that is based on ISO 9001 using the World Wide Web, a hypermedia system, and part of the Internet. Subject matter is presented as an alphabetical list of linked entries, numerous navigational techniques are available, and searching options function within an index file.…

  17. 77 FR 6169 - Defense Trade Advisory Group; Notice of Membership

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-07

    ... AGENCY: Department of State. ACTION: Notice. The U.S. Department of State's Bureau of Political-Military...-Military Affairs is interested in applications from subject matter experts from the United States defense...-Military Affairs with a formal channel for regular consultation and coordination with U.S. private sector...

  18. The Draw-an-Archaeologist Test

    ERIC Educational Resources Information Center

    Renoe, Susan

    2003-01-01

    The Draw-an-Archaeologist Test (DART) is an easy way to elicit students' conceptions about archaeology and can be adapted to other subject matter. When implemented as the first activity of an archaeology unit, it provides a starting point for introducing archaeology and addressing students' misconceptions about it. In this drawing activity,…

  19. NATAL-74; Towards a Common Programming Language for CAL.

    ERIC Educational Resources Information Center

    Brahan, J. W.; Colpitts, B. A.

    NATAL-74 is a programing language designed for Canadian computer aided learning (CAL) programs. The language has two fundamental elements: the UNIT provides the interface between the student and the subject matter, and the PROCEDURE element embodies teaching strategy. Desirable features of several programing languages have been adapted to cope…

  20. Eighth Grade Social Studies. An Experimental Program in Geography and Anthropology.

    ERIC Educational Resources Information Center

    Hanson, James; And Others

    GRADES OR AGES: Grade 8. SUBJECT MATTER: Geography and Anthropology. ORGANIZATION AND PHYSICAL APPEARANCE: The introductory material includes descriptions of geography and anthropology as disciplines, the basic course objectives, techniques for evaluating objectives and a student self-evaluation form. The guide covers six units: 1) "What Kind of…

  1. Science, Technology and Society as Experienced through Children's Literature.

    ERIC Educational Resources Information Center

    Butzow, Carol M.; Butzow, John W.

    In order to prepare children for the responsibilities of citizenship in a technological society, the Science, Technology and Society (STS) approach, which integrates various subject matter disciplines, can be implemented through the use of children's literature. In this way, STS units combine language arts, reading and literature, and teach and…

  2. Topic Outlines in Microbiology: An Instructor's Guide for Junior and Community Colleges.

    ERIC Educational Resources Information Center

    American Society for Microbiology, Washington, DC.

    This resource guide presents subject matter organized in outline form for four topical areas: introductory microbiology; medical microbiology; microbial genetics; and microbial physiology. The first two units comprise the two most frequently taught microbiology courses in community and junior colleges. The outlines for microbial genetics and…

  3. 78 FR 46614 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-01

    ... substantial interest in the subject matter of the investigations may request a public hearing, provided such... below, not later than August 12, 2013. Interested persons are invited to submit written comments...--United Health Group-- Minnetonka, MN........ 07/15/13 07/12/13 Remote Medical Transcription/Editing...

  4. A bibliography for the northern Madrean Biogeographic Province

    Treesearch

    Peter F. Ffolliott; Leonard F. DeBano; Gerald J. Gottfried; Daniel P. Huebner; Carl B. Edminster

    1999-01-01

    An online bibliography was compiled to furnish a literature basis for implementing of land management activities and planning research endeavors in the Madrean Biogeographic Province, which includes the Madrean Archipelago region in the southwestern United States. Citations are listed alphabetically by author in categories appropriate to the subject-matter presented....

  5. Public Law 94-553-Oct. 19, 1976. An Act For the General Revision of the Copyright Law, Title 17 of the United States Code, and for Other Purposes. Title 17-Copyrights. Ninety-Fourth Congress.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC.

    The copyright law of the United States is amended in its entirety by this act that takes effect in 1978. Literary works; musical works; dramatic works; pantomimes and choreographic works; pictorial, graphic, and sculptural works; motion pictures and other audiovisual works; and sound recordings are included in the subject matter of copyright.…

  6. Speaking of Salaries: What It Will Take to Get Qualified, Effective Teachers in All Communities

    ERIC Educational Resources Information Center

    Adamson, Frank; Darling-Hammond, Linda

    2011-01-01

    The fact that well-qualified teachers are inequitably distributed to students in the United States has received growing public attention. By every measure of qualifications--certification, subject matter background, pedagogical training, selectivity of college attended, test scores, or experience--less-qualified teachers tend to be found in…

  7. Of "Chicharrones" and Clam Chowder: Gender and Consumption in Jorge Ulica's Cronicas Diabolicas

    ERIC Educational Resources Information Center

    Barrera, Magdalena

    2009-01-01

    This essay examines the working-class Mexican experience as represented in Jorge Ulica's "Cronicas Diabolicas," which he published between 1916 and 1926. What unites the wide-ranging subject matter of the chronicles is the author's resolute interest in maintaining his working-class compatriots' cultural and ideological ties to Mexico.…

  8. A Generalization of "n Choose r"

    ERIC Educational Resources Information Center

    Skurnick, Ronald

    2005-01-01

    The subject matter presented in this article can be used in the classroom to enrich the learning experience of students taking a course that includes a unit on combinatorics, such as discrete mathematics, graph theory, or probability. In order to provide such students with the background needed to appreciate the significance of the generalization…

  9. Issues in Ethnic Minority Education in the United States.

    ERIC Educational Resources Information Center

    Parker, Sandra M.

    Perceiving ethnic minority schools merely as institutions which provide competency in the language of heritage is a limited view. History, values, and cultural traditions are also within the curricula of most ethnic schools. The subject matter often conflicts with modern American values, which stress change and mobility rather than tradition. In…

  10. Monarch Butterflies: Spirits of Loved Ones

    ERIC Educational Resources Information Center

    Crumpecker, Cheryl

    2011-01-01

    The study of the beautiful monarch butterfly lends itself to a vast array of subject matter, and offers the opportunity to meet a large and varied number of standards and objectives for many grade levels. Art projects featuring monarchs may include many cross-curricular units such as math (symmetry and number graphing), science (adaptation and…

  11. LAW ENFORCEMENT OFFICER TRAINING, BASIC COURSE, UNIT II, INSTRUCTOR'S MANUAL.

    ERIC Educational Resources Information Center

    REESE, ROBERT M.; AND OTHERS

    INSTRUCTORS MAY USE THIS MANUAL IN CONDUCTING A TRAINING PROGRAM FOR INSERVICE LAW ENFORCEMENT OFFICERS AND RECRUITS. IT WAS DEVELOPED BY A STATEWIDE COMMITTEE OF STATE LAW ENFORCEMENT CONSULTANTS, SPECIALISTS, AND AN ADVISORY COMMITTEE AND WAS TESTED BY A SUBJECT-MATTER SPECIALIST IN PILOT-CLASS STUDY. THE TRAINING PROGRAM IS DESIGNED TO PROVIDE…

  12. Success and Failure in Adult Education: The Immigrant Experience 1914-1924.

    ERIC Educational Resources Information Center

    Seller, Maxine S.

    The educational experience of adult immigrants to the United States between 1914-24 is discussed. Attempts of educators and Americanization agencies to reach adult immigrants are described and reasons for the failure of these attempts are given, including inadequate funding, narrowness in subject matter and methods, and insensitivity to ethnic…

  13. Energized Learning

    Science.gov Websites

    Energized Learning Students Lessons Bullet Getting Started Bullet Bringing It Home Bullet Unit activities with keys to subject matter standards. As students work through one or more of the standards-based Why Use the Energized Learning Site? How will teachers and Students Use the Energized Learning Site

  14. Seventh Grade Social Studies. A Program in Sociology and American History.

    ERIC Educational Resources Information Center

    Clancy, Patricia; And Others

    GRADES OR AGES: Seventh grade. SUBJECT MATTER: Sociology and American history. ORGANIZATION AND PHYSICAL APPEARANCE: The guide covers five units: "Biological Basis of Human Behavior,""How We Become Human,""The Family and Other Socializing Institutions,""Man's Behavior in Groups and Crowds," and "Minority Group Problems." The presentation of the…

  15. A Program for High School Social Studies: Anthropology.

    ERIC Educational Resources Information Center

    Haviland, Pam

    GRADES OR AGES: High School. SUBJECT MATTER: Anthropology. ORGANIZATION AND PHYSICAL APPEARANCE: The guide covers three units: 1) "The Study of Man"; 2) "Introduction to Physical Anthropology," including the process of evolution, descent and change in time, chronology of events, dawn of man, fossil man, race, and definitions of race; and 3)…

  16. Integrating Reading Instruction into Vocational Agriculture Classes. Miscellaneous Publication 586. Contribution Number 3813.

    ERIC Educational Resources Information Center

    Sullivan, Dorothy D.; Cardozier, V.R.

    An experiment was conducted to determine whether special reading instruction integrated with agricultural instruction would result in improved reading ability and increased achievement in subject matter. random assignment was made of vocational agriculture classes in 12 Maryland schools to experimental and control groups. Units on soil sampling…

  17. An Evaluation of a Biological Slide-Tutorial Program.

    ERIC Educational Resources Information Center

    Chan, Gordon L.

    Described is an auto-tutorial slide program for zoology students. A self-paced system was devised for observing the subject matter covered in the twelve study units of a zoology course. The post-testing evaluation revealed that students with lower grade point averages achieved scores comparable with students of higher grade point averages.…

  18. 48 CFR 52.227-10 - Filing of Patent Applications-Classified Subject Matter.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... application to the United States Patent Office, but the Contractor shall not be denied the right to file the... States Patent Office, the Contractor shall by separate letter identify by agency and number the contract... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Filing of Patent...

  19. 48 CFR 52.227-10 - Filing of Patent Applications-Classified Subject Matter.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... application to the United States Patent Office, but the Contractor shall not be denied the right to file the... States Patent Office, the Contractor shall by separate letter identify by agency and number the contract... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Filing of Patent...

  20. 48 CFR 52.227-10 - Filing of Patent Applications-Classified Subject Matter.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... application to the United States Patent Office, but the Contractor shall not be denied the right to file the... States Patent Office, the Contractor shall by separate letter identify by agency and number the contract... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Filing of Patent...

  1. 48 CFR 52.227-10 - Filing of Patent Applications-Classified Subject Matter.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... application to the United States Patent Office, but the Contractor shall not be denied the right to file the... States Patent Office, the Contractor shall by separate letter identify by agency and number the contract... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Filing of Patent...

  2. 48 CFR 52.227-10 - Filing of Patent Applications-Classified Subject Matter.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... application to the United States Patent Office, but the Contractor shall not be denied the right to file the... States Patent Office, the Contractor shall by separate letter identify by agency and number the contract... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Filing of Patent...

  3. Examining Student-Designed Games through Suits' Theory of Games

    ERIC Educational Resources Information Center

    Casey, Ashley; Hastie, Peter; Jump, Steve

    2016-01-01

    This paper documents how a unit of student-designed games can create a more meaningful version of physical education (PE) for disengaged students, a version that enhances the educational legitimacy of the subject matter by affording it worth in and of itself rather than being justified for other, extrinsic or instrumental reasons. Furthermore, it…

  4. Soil property effects on wind erosion of organic soils

    USDA-ARS?s Scientific Manuscript database

    Histosols (also known as organic soils, mucks, or peats) are soils that are dominated by organic matter (>20%) in half or more of the upper 80 cm. Forty four states have a total of 21 million ha of histosols in the United States. These soils, when intensively cropped, are subject to wind erosion r...

  5. Soil Property Effects on Wind Erosion of Organic Soils

    USDA-ARS?s Scientific Manuscript database

    Histosols (also known as organic soils, mucks, or peats) are soils that are dominated by organic matter (>20%) in half or more of the upper 80 cm. Forty four states have a total of 21 million ha of histosols in the United States. These soils, when intensively cropped, are subject to wind erosion r...

  6. A Management Scientist Looks at Education and Education Looks Back.

    ERIC Educational Resources Information Center

    Ackoff, Russell L.

    Three fundamental educational issues which are usually ignored in favor of more trival operating problems are identified as follows: how can the educational process be redesigned to focus on the learning, not teaching, process; how to avoid organizing education around rigid schedules and artifically quantified units of subject matter and instead…

  7. Here Comes the Future.

    ERIC Educational Resources Information Center

    Reeder, Robert; And Others

    This teacher's guide introduces students to problems and potentials of the future in an effort to prepare them for life in the 21st century. Based on an interdisciplinary approach, the lesson plans within four major units represent five futuristic trends and assumptions: (1) the shift of emphasis from subject matter to conceptual frameworks; (2)…

  8. Technical Reference Manual to Allied Medical Publication 7.5 (AMedP 7.5) NATO Planning Guide for the Estimation of CBRN Casualties

    DTIC Science & Technology

    2016-10-01

    Response Subject Matter Expert Review Meeting, 23-25 June 2008, Albuquerque, New Mexico , United States of America, IDA Document D-3884 (Alexandria, VA...Meeting, 26 June 2008, Albuquerque, New Mexico , United States of America, IDA Document D-3885 (Alexandria, VA: Institute for Defense Analyses, August...26 June 2008 radiological human response meetings in Albuquerque, New Mexico :  Canada – Commander Ian Torrie, CFHSG-DHSO – Diana Wilkinson, DRDC

  9. National Proceedings: Forest and Conservation Nursery Associations-2009

    Treesearch

    L. E. Riley; J. R. Pinto; R. K. Dumroese

    2010-01-01

    These proceedings are a compilation of 20 papers that were presented at the regional meetings of the Intertribal Nursery Council and the forest and conservation nursery associations in the United States in 2009. The Intertribal Nursery Council Meeting was held at the Best Western University Inn in Moscow, Idaho, on July 14, 2009. Subject matter for the technical...

  10. Popcorn. A Language Development Unit for Science. Matter and Energy. Grade One.

    ERIC Educational Resources Information Center

    Gilmour, Margy; McGregor, Cathy, Ed.

    One of the basic principles of the Language Development Approach is that students must learn the language necessary to understand, talk, and write about all subject areas in order to succeed in school. This book contains information about teaching primary school science in the Northwest Territories with lessons that emphasize language. The goals…

  11. Improved density discrimination using agfacontour film

    NASA Technical Reports Server (NTRS)

    Goodding, R. A.

    1973-01-01

    A technique was developed for obtaining tone separations from black and white photographic materials. Agfacontour film and photographic derivatives are utilized to improve the density discrimination and decrease the density range from 0.45 to 0.08 units. This increase in capability extends the usefulness of tone separations to a wider range of subject matter and problem areas.

  12. National Proceedings: Forest and Conservation Nursery Associations - 2013

    Treesearch

    K. M. Wilkinson; D. L. Haase; J. R. Pinto

    2014-01-01

    These proceedings are a compilation of 14 papers that were presented at the regional meetings of the forest and conservation nursery associations in the United States in 2013. The Joint Northeast and Southern Forest Nursery Conference was held at the Holiday Inn City Centre, Lafayette, Indiana, July 22 to 25, 2013. Subject matter for the technical sections included...

  13. Greenhouse Crop Production; A Student Handbook, Teacher Education Series, Volume 10 Number 3s.

    ERIC Educational Resources Information Center

    1969

    This study guide, developed by the Department of Agricultural Education of The Pennsylvania State University and field-tested by 54 teachers, is for student use in a unit on greenhouse crop production. Learning objectives, key questions, vocabulary terms, subject matter, and references are included for each of these problem areas: (1) Occupational…

  14. A Study of Disciplinary, Structural, and Behavioral Effects on Course Outcomes in Online MBA Courses

    ERIC Educational Resources Information Center

    Arbaugh, J. B.; Rau, Barbara L.

    2007-01-01

    This article reports the results of a 2-year study examining the effects of subject matter, course structure, and participant behaviors on students' perceived learning and satisfaction with delivery medium in Web-based courses of an MBA program in the midwestern United States. Using finance as the referent discipline, we found statistically…

  15. Incorporating Scientific Argumentation into Inquiry-Based Activities with Online Personally Seeded Discussions

    ERIC Educational Resources Information Center

    Sampson, Victor; Clark, Douglas

    2007-01-01

    An explicit goal of the current reform movement in science education is to promote scientific literacy in the United States. One way to encourage scientific literacy is to help students develop a better understanding of science subject matter, that is, the declarative knowledge specifically associated with the physical, life, and earth sciences.…

  16. You and Man in the Western World. A Cultural Approach. Eighth Grade Social Studies.

    ERIC Educational Resources Information Center

    Parsippany - Troy Hills Board of Education, Parsippany, NJ.

    GRADES OR AGES: Grade 8. SUBJECT MATTER: Social Studies--You and Man in the Western World. ORGANIZATION AND PHYSICAL APPEARANCE: The guide contains five units: 1) cultural orientation; 2) social studies dimensions in Western Europe; 3) social studies dimensions in Eastern Europe and Soviet Union; 4) social studies dimensions in Latin America; and…

  17. World History. A Program for Senior High School Social Studies.

    ERIC Educational Resources Information Center

    Waldner, Patrick

    GRADES OR AGES: Senior high school. SUBJECT MATTER: World history. ORGANIZATION AND PHYSICAL APPEARANCE: The guide covers ten units: 1) Perspective--Man in Pre-historic and Ancient Times; 2) Feudalism and the Church in the Middle Ages; 3) Renaissance and Reformation; 4) The Emergence of Nationalism--Its Cause and Effects; 5) Revolutions of Rising…

  18. Man's Basic Needs. Resource Units, Grade 1. Providence Social Studies Curriculum Project.

    ERIC Educational Resources Information Center

    Providence Public Schools, RI.

    GRADES OR AGES: Grade 1. SUBJECT MATTER: Social studies; man's basic needs. ORGANIZATION AND PHYSICAL APPEARANCE: The guide is divided into 11 chapters, five of which outline the basic curriculum subunits. These five chapters are laid out in three columns, one each for topics, activities, and materials. Other chapters are in list form. The guide…

  19. Military Curricula for Vocational & Technical Education. Packing and Unitization, 19-2.

    ERIC Educational Resources Information Center

    Joint Military Packaging Training Center, Aberdeen Proving Ground, MD.

    This correspondence course on methods and techniques of packing materials and equipment for shipment and storage is designed to familiarize students with the subject matter area and to serve as a background for a more detailed and specialized study. One of a number of military-developed curriculum packages selected for adaptation to vocational…

  20. 76 FR 81968 - United States v. Deutsche Börse AG and NYSE Euronext; Proposed Final Judgment and Competitive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ....S.C. Sec. 18. 6. The Court has subject matter jurisdiction over this action and the defendants... ``dark'' equities trading services, including the continuous pre- trade publication of the best-priced... undisplayed equity trading services, like dark pools, which offer no pre-trade transparency and cater mainly...

  1. The Importance of Comparative Law in Legal Education: United States Goals and Methods of Legal Comparison

    ERIC Educational Resources Information Center

    Ault, Hugh J.; Glendon, Mary Ann

    1976-01-01

    Discusses the rationale for teaching comparative law and describes techniques and results of experiments with two kinds of courses at Boston College Law School: (1) Comparative Legal Analysis, a perspective course, and (2) integration of comparative law as another dimension into courses in a particular subject matter area. (JT)

  2. Defining and Using the Subject Matter Expert's Role in Transforming Army Training and Education Programs

    ERIC Educational Resources Information Center

    Wilson, William Rollyn

    2009-01-01

    The United States Army is a complex and diverse organization that must keep pace with the changing global environment to meet its Constitutional responsibility to fight and win the nation's wars. Today, organizations, doctrine, logistics, material, facilities, concepts, techniques, procedures, and training and education are all changing to meet…

  3. 19 CFR 174.11 - Matters subject to protest.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 2 2013-04-01 2013-04-01 false Matters subject to protest. 174.11 Section 174.11... TREASURY (CONTINUED) PROTESTS Protests § 174.11 Matters subject to protest. The following decisions of CBP... administrative decisions involving the following subject matters are subject to protest: (1) The appraised value...

  4. 19 CFR 174.11 - Matters subject to protest.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 2 2014-04-01 2014-04-01 false Matters subject to protest. 174.11 Section 174.11... TREASURY (CONTINUED) PROTESTS Protests § 174.11 Matters subject to protest. The following decisions of CBP... administrative decisions involving the following subject matters are subject to protest: (1) The appraised value...

  5. 19 CFR 174.11 - Matters subject to protest.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 2 2011-04-01 2011-04-01 false Matters subject to protest. 174.11 Section 174.11... TREASURY (CONTINUED) PROTESTS Protests § 174.11 Matters subject to protest. The following decisions of CBP... administrative decisions involving the following subject matters are subject to protest: (1) The appraised value...

  6. 19 CFR 174.11 - Matters subject to protest.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 2 2012-04-01 2012-04-01 false Matters subject to protest. 174.11 Section 174.11... TREASURY (CONTINUED) PROTESTS Protests § 174.11 Matters subject to protest. The following decisions of CBP... administrative decisions involving the following subject matters are subject to protest: (1) The appraised value...

  7. Annotated bibliography of fire literature relative to northern grasslands in south-central Canada and north-central United States

    USGS Publications Warehouse

    Higgins, Kenneth F.; Fellows, David P.; Callow, J. Mike; Kruse, Arnold D.; Piehl, James L.

    1989-01-01

    Natural resource managers have greatly increased the use of fire to manage grassland habitats during the past two decades in the northern Great Plains region of the United States and Canada. In support of these efforts, we have compiled this annotated bibliography to provide a condensed reference of fire literature for those managers with an interest in fire ecology. References are arranged alphabetically by author and year, numbered consecutively, and referenced by number in the author and subject indexes that follow the bibliography. The intent in compiling the bibliography and indexes is more to identify subject matter and to direct the reader to sources rather than to provide a digested interpretation of each manuscript.

  8. Motion of Information Industry Association for Leave to File Brief Amicus Curiae and Brief of Information Industry Association Amicus Curiae [in the Case of Donald Goldstein et. al. v. State of California, in the Matter of State vs. Federal Copyright Infringement Remedies.] In the Supreme Court of the United States, October Term, 1971.

    ERIC Educational Resources Information Center

    Zurkowski, Paul G.

    The question raised here, whether state criminal laws can be applied to subject matter also addressed by federal copyright law, is of immediate interest to the information industry. This brief Amicus Curiae deals with the need of the industry and the public generally for remedies on which the growth of the information tools and resources needed to…

  9. Brief report on the United States Food and Drug Administration Blood Products Advisory Committee recommendations for management of donors and units testing positive for hepatitis B virus DNA.

    PubMed

    Lucey, C

    2006-11-01

    This article briefly recounts the 21st July 2005, Blood Products Advisory Committee (BPAC) meeting concerning recommendations for management of donors and units testing positive for hepatitis B virus (HBV) DNA. The author attended the meeting. The United States Food and Drug Administration (FDA) web site was used for meeting materials, and handouts were collected at the meeting to provide narrative information. Two European experts assisted with HBV subject matter. The proceedings of the advisory committee, the issue briefing materials, and testing algorithms are presented. BPAC voted concurrence with the FDA algorithm for Management of Donors and Units Testing Positive for Hepatitis B Virus DNA.

  10. 45 CFR 703.3 - Scope of subject matter.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Scope of subject matter. 703.3 Section 703.3... AND FUNCTIONS OF STATE ADVISORY COMMITTEES § 703.3 Scope of subject matter. The scope of the subject matter to be dealt with by Advisory Committees shall be those subjects of inquiry or study with which the...

  11. 45 CFR 703.3 - Scope of subject matter.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Scope of subject matter. 703.3 Section 703.3... AND FUNCTIONS OF STATE ADVISORY COMMITTEES § 703.3 Scope of subject matter. The scope of the subject matter to be dealt with by Advisory Committees shall be those subjects of inquiry or study with which the...

  12. 45 CFR 703.3 - Scope of subject matter.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Scope of subject matter. 703.3 Section 703.3... AND FUNCTIONS OF STATE ADVISORY COMMITTEES § 703.3 Scope of subject matter. The scope of the subject matter to be dealt with by Advisory Committees shall be those subjects of inquiry or study with which the...

  13. 45 CFR 703.3 - Scope of subject matter.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Scope of subject matter. 703.3 Section 703.3... AND FUNCTIONS OF STATE ADVISORY COMMITTEES § 703.3 Scope of subject matter. The scope of the subject matter to be dealt with by Advisory Committees shall be those subjects of inquiry or study with which the...

  14. 45 CFR 703.3 - Scope of subject matter.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Scope of subject matter. 703.3 Section 703.3... AND FUNCTIONS OF STATE ADVISORY COMMITTEES § 703.3 Scope of subject matter. The scope of the subject matter to be dealt with by Advisory Committees shall be those subjects of inquiry or study with which the...

  15. An Example-Based Multi-Atlas Approach to Automatic Labeling of White Matter Tracts

    PubMed Central

    Yoo, Sang Wook; Guevara, Pamela; Jeong, Yong; Yoo, Kwangsun; Shin, Joseph S.; Mangin, Jean-Francois; Seong, Joon-Kyung

    2015-01-01

    We present an example-based multi-atlas approach for classifying white matter (WM) tracts into anatomic bundles. Our approach exploits expert-provided example data to automatically classify the WM tracts of a subject. Multiple atlases are constructed to model the example data from multiple subjects in order to reflect the individual variability of bundle shapes and trajectories over subjects. For each example subject, an atlas is maintained to allow the example data of a subject to be added or deleted flexibly. A voting scheme is proposed to facilitate the multi-atlas exploitation of example data. For conceptual simplicity, we adopt the same metrics in both example data construction and WM tract labeling. Due to the huge number of WM tracts in a subject, it is time-consuming to label each WM tract individually. Thus, the WM tracts are grouped according to their shape similarity, and WM tracts within each group are labeled simultaneously. To further enhance the computational efficiency, we implemented our approach on the graphics processing unit (GPU). Through nested cross-validation we demonstrated that our approach yielded high classification performance. The average sensitivities for bundles in the left and right hemispheres were 89.5% and 91.0%, respectively, and their average false discovery rates were 14.9% and 14.2%, respectively. PMID:26225419

  16. An Example-Based Multi-Atlas Approach to Automatic Labeling of White Matter Tracts.

    PubMed

    Yoo, Sang Wook; Guevara, Pamela; Jeong, Yong; Yoo, Kwangsun; Shin, Joseph S; Mangin, Jean-Francois; Seong, Joon-Kyung

    2015-01-01

    We present an example-based multi-atlas approach for classifying white matter (WM) tracts into anatomic bundles. Our approach exploits expert-provided example data to automatically classify the WM tracts of a subject. Multiple atlases are constructed to model the example data from multiple subjects in order to reflect the individual variability of bundle shapes and trajectories over subjects. For each example subject, an atlas is maintained to allow the example data of a subject to be added or deleted flexibly. A voting scheme is proposed to facilitate the multi-atlas exploitation of example data. For conceptual simplicity, we adopt the same metrics in both example data construction and WM tract labeling. Due to the huge number of WM tracts in a subject, it is time-consuming to label each WM tract individually. Thus, the WM tracts are grouped according to their shape similarity, and WM tracts within each group are labeled simultaneously. To further enhance the computational efficiency, we implemented our approach on the graphics processing unit (GPU). Through nested cross-validation we demonstrated that our approach yielded high classification performance. The average sensitivities for bundles in the left and right hemispheres were 89.5% and 91.0%, respectively, and their average false discovery rates were 14.9% and 14.2%, respectively.

  17. Model Rocketry in the High School. Grades 9-12. Course Guide.

    ERIC Educational Resources Information Center

    Grossenbacher, Roger

    This document describes a general introductory course in applied science intended for students of various interests and abilities. The course is designed to provide high school students with a basic understanding of the space age with an emphasis on model rocketry. Included is an outline of the subject matter to be covered in units on: (1)…

  18. Home Economics Education. Course of Study for Occupationally Oriented Classes. Grades 8, 9, 10.

    ERIC Educational Resources Information Center

    Fairfax County Schools, VA.

    GRADES OR AGES: Grades 8-10. SUBJECT MATTER: Vocational home economics. ORGANIZATION AND PHYSICAL APPEARANCE: The guide is divided into three sections, one for each grade. Sections are further subdivided into units, each of which is laid out in three columns. Column headings are goals and concepts, activities and resources and notes. The guide is…

  19. A Qualitative Study on Knowledge Transfer among Members of the United States Intelligence Community

    ERIC Educational Resources Information Center

    Keshavarz-Nia, Navid R.

    2011-01-01

    This study sought to examine the relationship between social interaction and tacit knowledge transfer, as a dyadic exchange of critical knowledge between a Subject Matter Expert (SME) and a Knowledge Recipient (KR). Knowledge was defined as information and know-how, not merely as organized data or a system, but an active social process that was…

  20. The Influence of High-Stakes Testing on Teacher Self-Efficacy and Job-Related Stress

    ERIC Educational Resources Information Center

    Gonzalez, Alejandro; Peters, Michelle L.; Orange, Amy; Grigsby, Bettye

    2017-01-01

    In the United States, teachers' job-related stress and self-efficacy levels across all grades are influenced in some manner by the demands of high-stakes testing. This sequential mixed-methods study aimed at examining the dynamics among assigned subject matter, teacher job-related stress, and teacher self-efficacy in a large south-eastern Texas…

  1. School Camping? What's It All About? Taft Campus Occasional Papers, No. II.

    ERIC Educational Resources Information Center

    Donaldson, George W.

    School camping began in the United States in the 1940's and underwent expansion on a grand scale during the 1950's; in 1967, it reached more than one-half million students in over 1000 school districts. The philosophy of early school camps was almost totally activity-centered, with little emphasis on formal curricular subject matter, such as…

  2. The Development of a Model for Construction of Criterion Referenced System Achievement Tests for the Strategic Weapon System Training Program.

    ERIC Educational Resources Information Center

    Cantor, Jeffrey A.; Hobson, Edward N.

    The development of a test design methodology used to construct a criterion-referenced System Achievement Test (CR-SAT) for selected Naval enlisted classification (NEC) in the Strategic Weapon System (SWS) of the United States Navy is described. Subject matter experts, training data analysts and educational specialists developed a comprehensive…

  3. A Comparative Analysis of Word Problems in Selected United States and Russian First Grade Textbooks

    ERIC Educational Resources Information Center

    Grishchenko, Svetlana

    2009-01-01

    The purpose of this study was to explore word problems as a subject matter in mathematics textbook curricula. The motivation for the study derived from the following evidence: (a) American students find some word problems are more difficult than others (Garcia, Jimenez, & Hess, 2006; Riley & Green, 1988; Stern, 2001), and (b) one of the…

  4. Teachers' Cultural Maps: Asia as a "Tricky Sort of Subject Matter" in Curriculum Inquiry

    ERIC Educational Resources Information Center

    Salter, Peta

    2014-01-01

    The refocussing of Australia-Asia relations is manifest in a combination of national policy moves in Australia. Parallel shifts have been made in Europe, the United States, Canada and New Zealand. In Australia, the curricular response to this shift has become known as "Asia literacy." This study is drawn from a wider project that…

  5. 78 FR 37788 - In the Matter of: Juan Ricardo Puente-Paez, Inmate Number #05086-379, FCI McDowell, Federal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-24

    ... exported from the United States to Mexico four military spec Interceptor body armor vests, which were... owned, possessed or controlled by the Denied Person, or service any item, of whatever origin, that is... subject to the Regulations are the foreign-produced direct product of U.S.-origin technology. V. This...

  6. The Robustness of Designs for Trials with Nested Data against Incorrect Initial Intracluster Correlation Coefficient Estimates

    ERIC Educational Resources Information Center

    Korendijk, Elly J. H.; Moerbeek, Mirjam; Maas, Cora J. M.

    2010-01-01

    In the case of trials with nested data, the optimal allocation of units depends on the budget, the costs, and the intracluster correlation coefficient. In general, the intracluster correlation coefficient is unknown in advance and an initial guess has to be made based on published values or subject matter knowledge. This initial estimate is likely…

  7. Fast Automatic Segmentation of White Matter Streamlines Based on a Multi-Subject Bundle Atlas.

    PubMed

    Labra, Nicole; Guevara, Pamela; Duclap, Delphine; Houenou, Josselin; Poupon, Cyril; Mangin, Jean-François; Figueroa, Miguel

    2017-01-01

    This paper presents an algorithm for fast segmentation of white matter bundles from massive dMRI tractography datasets using a multisubject atlas. We use a distance metric to compare streamlines in a subject dataset to labeled centroids in the atlas, and label them using a per-bundle configurable threshold. In order to reduce segmentation time, the algorithm first preprocesses the data using a simplified distance metric to rapidly discard candidate streamlines in multiple stages, while guaranteeing that no false negatives are produced. The smaller set of remaining streamlines is then segmented using the original metric, thus eliminating any false positives from the preprocessing stage. As a result, a single-thread implementation of the algorithm can segment a dataset of almost 9 million streamlines in less than 6 minutes. Moreover, parallel versions of our algorithm for multicore processors and graphics processing units further reduce the segmentation time to less than 22 seconds and to 5 seconds, respectively. This performance enables the use of the algorithm in truly interactive applications for visualization, analysis, and segmentation of large white matter tractography datasets.

  8. Effects of white matter lesions on brain perfusion in patients with mild cognitive impairment.

    PubMed

    Ishibashi, Masato; Kimura, Noriyuki; Aso, Yasuhiro; Matsubara, Etsuro

    2018-05-01

    To evaluate the effects of white matter lesions on regional cerebral blood flow in subjects with amnestic mild cognitive impairment. Seventy-five subjects with mild cognitive impairment (36 men and 39 women; mean age, 78.1 years) were included in the study. We used the Mini-Mental State Examination to assess cognitive function. All subjects underwent brain magnetic resonance imaging and 99m Tc ethylcysteinate dimer single photon emission computed tomography. Subjects were stratified based on the presence or absence of white matter lesions on magnetic resonance imaging. Statistical parametric mapping of differences in regional cerebral blood flow between the two groups were assessed by voxel-by-voxel group analysis using SPM8. Of all 75 subjects with mild cognitive impairment, 46 (61.3%) had mild to moderate white matter lesions. The prevalence of hypertension tended to be higher in subjects with white matter lesions than in those without white matter lesions. Mini-Mental State Examination scores were significantly lower in subjects with white matter lesions than in those without white matter lesions. Subjects with white matter lesions had decreased regional cerebral blood flow mainly in the frontal, parietal, and medial temporal lobes, as well as the putamen, compared to those without white matter lesions. In subjects with mild cognitive impairment, white matter lesions were associated with cognitive impairment and mainly frontal lobe brain function. Copyright © 2018 Elsevier B.V. All rights reserved.

  9. Let Me Entertain You: The Exciting Perks and Perils of Teaching American Religion as a Vaudeville (Or Burlesque?) Performer

    ERIC Educational Resources Information Center

    Shrout, Katy E.

    2009-01-01

    While teaching a course on religion and consumer culture in the United States, the author was intensely preoccupied with holding the interest of her undergraduate students during class sessions. Inspired in part by the subject matter of the course, she reflects here upon the extent that her courses on American religion drew upon the semiotics of…

  10. Methodology to Improve Aviation Security With Terrorist Using Aircraft as a Weapon

    DTIC Science & Technology

    2013-09-01

    STATEMENT Approval for public release;distribution is unlimited 12b. DISTRIBUTION CODE 13. ABSTRACT (maximum 200 words ) The aviation industry... Electronic Baggage Screening Program EDS Explosive Detection System EMMI Energy, Matter, Material wealth, and Information ETD Explosives Trace...12 All checked baggage in the United States has been subjected to 100% screening since December 2003 under TSA’s Electronic Baggage Screening

  11. Contextual essay for integrated thematic unit: Kids, Quarks, and Quanta

    NASA Astrophysics Data System (ADS)

    Draeger, Vicki Lee

    This essay provides the research and rationale to support the theory that early adolescence is the best time to present an introduction to quantum mechanics. It supports the creation of an integrated thematic unit to be used with students ages 11--14 in an inclusion classroom without limiting the unit to only an inclusion setting. The first section sets forth five problems the unit was written to address. Citing The National Center for Education Statistics 2000 version of The Nation's Report Card, the problems with current practices in science education resulting in poor student performance are presented. References to Project 2061: Science for All Americans help to demonstrate that students with disabilities are seldom considered when physical science curriculum is being developed, supporting the position that equity in science education is necessary, while maintaining challenging subject matter. The problem of the poor quality of many physical science texts is addressed, with an emphasis on the importance of curricular connections. The poor quality of physical science teacher training in many university teacher training courses is discussed, and the nature of the integrated thematic unit as a curriculum design is examined with reference to what is considered the over-emphasis on "reality-based" content to the exclusion of abstract subject matter. Having presented the problems and supporting their validity, the essay then demonstrated how Kids, Quarks, and Quanta specifically addresses each problem. The two and a half year study of Dr. John Hubisz and the committee he formed under The David and Lucille Packard Foundation grant to review and critique the physical science textbooks currently used with early adolescents is often referenced to support both the problems of teacher training and the poor quality of many texts. Recent brain research conducted by researchers of the National Institute of Mental Health is used to support the presentation of more abstract subject matter for the 11--14 year old student. The research shows that rapid neuron growth and pruning does not just occur in the first years of life. Early adolescence is a second time of rapid neuron growth that begins at age ten for girls and eleven for boys, with pruning taking place until age 24. The theory is that this is the time when abstract thinking is developing and a "use it or lose it" maxim applies. The essay promotes the importance of differentiating curriculum for all students, and includes a substantial literature review and bibliography.

  12. Teachers and students: Reflections on social control and future performance

    PubMed Central

    Vargas, Ernest A.; Fraley, Lawrence E.

    1984-01-01

    To instruct consists of arranging controls between teacher, student, and subject matter. Initial controls must emanate from the teacher since those of the subject matter are minimal, crude, or missing. Teachers mand students to behave in certain ways with respect to a given subject matter. Eventually, however, the teacher must transfer the teacher mediated and managed control of the student to natural controls functioning directly through student interaction with the subject matter. Difficulty in doing this occurs due to the reinforcers for both student and teacher derived from social contact. Nevertheless, the student eventually must be taught to interact with the subject matter independent of teacher involvement if the student is to maintain effective contact with the subject matter beyond the period of formal instruction. PMID:22478606

  13. 49 CFR 1108.3 - Matters subject to arbitration.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 8 2011-10-01 2011-10-01 false Matters subject to arbitration. 1108.3 Section... STATUTORY JURISDICTION OF THE SURFACE TRANSPORTATION BOARD § 1108.3 Matters subject to arbitration. (a) Any...) Arbitration under these provisions is limited to matters over which the STB has statutory jurisdiction and may...

  14. 49 CFR 1108.3 - Matters subject to arbitration.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 8 2012-10-01 2012-10-01 false Matters subject to arbitration. 1108.3 Section... STATUTORY JURISDICTION OF THE SURFACE TRANSPORTATION BOARD § 1108.3 Matters subject to arbitration. (a) Any...) Arbitration under these provisions is limited to matters over which the STB has statutory jurisdiction and may...

  15. 49 CFR 1108.3 - Matters subject to arbitration.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Matters subject to arbitration. 1108.3 Section... STATUTORY JURISDICTION OF THE SURFACE TRANSPORTATION BOARD § 1108.3 Matters subject to arbitration. (a) Any...) Arbitration under these provisions is limited to matters over which the STB has statutory jurisdiction and may...

  16. The Development of Man and His Culture: New World Prehistory. Grade Two. Teacher's Guide [And] Teacher Background Material [And] Pupil Text [And] Pupil's Study Guide [And] A Sequential Curriculum in Anthropology. Test: Form 2, Composite Form for Pre- and Post-test. Publications No. 28, 29, 30, 33 and 41.

    ERIC Educational Resources Information Center

    Austin, Carol E.; And Others

    The social studies unit includes a teaching guide, teacher background material, student text, study guide, and composite pretest/posttest. Subject matter focuses on archaeological methods, history of man in America, and the Hopi Indians in the past and present. The unit is part of the Anthropology Curriculum Project and is designed to be used in…

  17. Antarctic news clips - 1992

    NASA Astrophysics Data System (ADS)

    1992-07-01

    The newspaper and magazine stories selected for this book present only a sampling of one year's (July 1991 to July 1992) news coverage of Antarctica. The only requirement for inclusion in this publication is that the article's subject matter pertains or refers to Antarctica in some way - whether it is focused on the science done there, or on the people who play such a large part in the work accomplished, or on the issues related to it. No attempt has been made to correlate the number of articles, or their length, with the importance of the subjects treated. Clippings are provided to the Foundation by a service that searches for items containing the phrase 'National Science Foundation'. Identical versions of many stories, especially those written and distributed by wire services such as the Associated Press and United Press International, and by syndicated columnists, are published in numerous papers across the United States. Other articles are submitted from a variety of sources, including interested readers across the United States and in New Zealand.

  18. 76 FR 57036 - Notice of Change in Subject Matter of Agency Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ... FEDERAL DEPOSIT INSURANCE CORPORATION Notice of Change in Subject Matter of Agency Meeting... consideration at the meeting, on less than seven days' notice to the public, of the following matters... September 7, 2011, of the change in the subject matter of the meeting was practicable. Dated: September 13...

  19. 75 FR 47316 - National Science Board; Sunshine Act Meetings; Notice (Subject Matter Revised From Earlier Notice)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-05

    ... NATIONAL SCIENCE FOUNDATION National Science Board; Sunshine Act Meetings; Notice (Subject Matter... for the transaction of National Science Board business and other matters specified, as follows: Date and Time: August 12, 2010, at 3 p.m. EDT. Subject Matter: Review and Discussion of Current Mid-Scale...

  20. A Model for Situation and Threat Assessment

    DTIC Science & Technology

    2006-12-01

    CUBRC , Inc.) 8151 Needwood #T103 Derwood, MD 20855 UNITED STATES steinberg@cubrc.org A model is presented for situation and threat assessment...PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Subject Matter Expert (SME) Calspan-UB Research Center ( CUBRC , Inc.) 8151 Needwood #T103 Derwood, MD...1 A Model for Situation and Threat Assessment Alan Steinberg CUBRC , Inc. steinberg@cubrc.org November, 2005 2 Objectives • Advance the state-of

  1. Readings in American History (In Their Own Words), Book III. New Directions for the United States and Teacher's Guide.

    ERIC Educational Resources Information Center

    Abramowitz, Jack

    This skills-text is the third of four books in the series "Readings in American History." The materials allow opportunities to improve reading and comprehension skills in a subject matter context by using certain primary sources related to the topic. Book 3 covers the period from the Civil War to 1900. Each lesson includes short readings with…

  2. Let's Get Real: Deeper Learning and the Power of the Workplace. Deeper Learning Research Series. Policy Bulletin

    ERIC Educational Resources Information Center

    Hoffman, Nancy

    2015-01-01

    In the United States, we tend to assume that young people should become educated and then go to work, as though the two were entirely separate stages of life. This dichotomy blinds us to the fact that work itself can be a powerful means of education-giving students opportunities to apply academic subject matter to real-world problems, and pushing…

  3. Readings in American History (In Their Own Words), Book IV. The United States in the Twentieth Century and Teacher's Guide.

    ERIC Educational Resources Information Center

    Abramowitz, Jack

    This skills-text is one of four books in the series "Readings in American History." The materials allow opportunities to improve reading and comprehension skills in a subject matter context by using certain primary sources related to the topic. Book 4 covers the period from World War I through the Reagan years. Each lesson includes short readings…

  4. DNA Dilemma: A Perspective on Current U.S. Patent and Trademarh Office Philosophy Concerning Life Patents

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Franz, K.; Faletra, P.

    The lack of a solid set of criteria for determining patentability of subject matter - particularly subject matter dealing with life - has recently been of increasing public concern in the United States. Alarm for patent practices related to life systems ranges from patents being granted on biochemical processes and the knowledge of these processes to the patenting of entire organisms. One of the most volatile concerns is the patenting of human genes or parts of genes since this genetic material is the basic informational molecule for all life. Current patent law, legislated in 1952, has been interpreted by themore » U.S. Supreme Court to allow broad patents of DNA, biochemical processes, and what are generally considered 'inventions' of life systems. Several issues are addressed in this paper regarding the unsound reasoning underlying both the interpretation and execution of patent law. Lapses in logic provide a gateway for businesses and individuals to take patenting to an illogical and unworkable extreme. Patent Office disorder of this magnitude is unnecessary and has great potential for harming the mission that the patent office was designed to serve. Recently disclosed patent-granting guidelines suggest the United States Patent and Trademark Office is not upholding its Constitutional responsibility of promoting the progress of science.« less

  5. Effects of Subject-Area Degree and Classroom Experience on New Chemistry Teachers' Subject Matter Knowledge

    ERIC Educational Resources Information Center

    Nixon, Ryan S.; Campbell, Benjamin K.; Luft, Julie A.

    2016-01-01

    Science teachers need to understand the subject matter they teach. While subject matter knowledge (SMK) can improve with classroom teaching experience, it is problematic that many secondary science teachers leave the profession before garnering extensive classroom experience. Furthermore, many new science teachers are assigned to teach science…

  6. Body-Machine Interfaces after Spinal Cord Injury: Rehabilitation and Brain Plasticity.

    PubMed

    Seáñez-González, Ismael; Pierella, Camilla; Farshchiansadegh, Ali; Thorp, Elias B; Wang, Xue; Parrish, Todd; Mussa-Ivaldi, Ferdinando A

    2016-12-19

    The purpose of this study was to identify rehabilitative effects and changes in white matter microstructure in people with high-level spinal cord injury following bilateral upper-extremity motor skill training. Five subjects with high-level (C5-C6) spinal cord injury (SCI) performed five visuo-spatial motor training tasks over 12 sessions (2-3 sessions per week). Subjects controlled a two-dimensional cursor with bilateral simultaneous movements of the shoulders using a non-invasive inertial measurement unit-based body-machine interface. Subjects' upper-body ability was evaluated before the start, in the middle and a day after the completion of training. MR imaging data were acquired before the start and within two days of the completion of training. Subjects learned to use upper-body movements that survived the injury to control the body-machine interface and improved their performance with practice. Motor training increased Manual Muscle Test scores and the isometric force of subjects' shoulders and upper arms. Moreover, motor training increased fractional anisotropy (FA) values in the cingulum of the left hemisphere by 6.02% on average, indicating localized white matter microstructure changes induced by activity-dependent modulation of axon diameter, myelin thickness or axon number. This body-machine interface may serve as a platform to develop a new generation of assistive-rehabilitative devices that promote the use of, and that re-strengthen, the motor and sensory functions that survived the injury.

  7. Teaching about the Constitution: Relationships between Teachers' Subject Matter Knowledge, Pedagogic Beliefs and Instructional Decision Making regarding Selection of Content, Materials, and Activities. Summary of Research Findings.

    ERIC Educational Resources Information Center

    Hyland, John T.

    Importance of the Constitution as the supreme law of the land and the reported failure of the United States youth to have been genuinely educated about the Constitution raises questions regarding teaching. One concerns what teachers know about the Constitution and the other is what they believe about teaching. This study investigates these…

  8. 45 CFR 73.735-701 - General provisions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... of monetary value for any lecture, discussion, writing or appearance the subject matter of which is... value for any lecture, discussion, writing or appearance, the subject matter of which is not devoted to... consultation, lecture, discussion, writing or appearance, the subject matter of which is devoted substantially...

  9. 45 CFR 73.735-701 - General provisions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... of monetary value for any lecture, discussion, writing or appearance the subject matter of which is... value for any lecture, discussion, writing or appearance, the subject matter of which is not devoted to... consultation, lecture, discussion, writing or appearance, the subject matter of which is devoted substantially...

  10. 45 CFR 73.735-701 - General provisions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... of monetary value for any lecture, discussion, writing or appearance the subject matter of which is... value for any lecture, discussion, writing or appearance, the subject matter of which is not devoted to... consultation, lecture, discussion, writing or appearance, the subject matter of which is devoted substantially...

  11. 45 CFR 73.735-701 - General provisions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... of monetary value for any lecture, discussion, writing or appearance the subject matter of which is... value for any lecture, discussion, writing or appearance, the subject matter of which is not devoted to... consultation, lecture, discussion, writing or appearance, the subject matter of which is devoted substantially...

  12. Behaviorism

    ERIC Educational Resources Information Center

    Moore, J.

    2011-01-01

    Early forms of psychology assumed that mental life was the appropriate subject matter for psychology, and introspection was an appropriate method to engage that subject matter. In 1913, John B. Watson proposed an alternative: classical S-R behaviorism. According to Watson, behavior was a subject matter in its own right, to be studied by the…

  13. 22 CFR 61.6 - Consultation with subject matter specialists.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Consultation with subject matter specialists. 61.6 Section 61.6 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.6 Consultation with subject matter specialists. (a) The...

  14. 22 CFR 61.6 - Consultation with subject matter specialists.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Consultation with subject matter specialists. 61.6 Section 61.6 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.6 Consultation with subject matter specialists. (a) The...

  15. 22 CFR 61.6 - Consultation with subject matter specialists.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Consultation with subject matter specialists. 61.6 Section 61.6 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.6 Consultation with subject matter specialists. (a) The...

  16. 22 CFR 61.6 - Consultation with subject matter specialists.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Consultation with subject matter specialists. 61.6 Section 61.6 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.6 Consultation with subject matter specialists. (a) The...

  17. What Counts as Subject Matter Knowledge for Teaching?

    ERIC Educational Resources Information Center

    Thornton, Stephen J.

    Focusing on social studies, this paper asserts that taking traditional content courses by themselves may not necessarily significantly enhance teachers' subject matter competence. It suggests that preparing social studies teachers to enact curricula is more than a matter of assuring that they have enough work in the traditional academic subject.…

  18. 19 CFR 174.11 - Matters subject to protest.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Matters subject to protest. 174.11 Section 174.11 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED) PROTESTS Protests § 174.11 Matters subject to protest. The following decisions of the...

  19. 22 CFR 61.6 - Consultation with subject matter specialists.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Consultation with subject matter specialists. 61.6 Section 61.6 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.6 Consultation with subject matter specialists. (a) The...

  20. 78 FR 21345 - In the Matter of: Liem Duc Huynh, a/k/a Duc Huynh, 2905 South Elm, Broken Arrow, OK 74012; Order...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-10

    ... Economic Powers Act (50 U.S.C. 1701-1706); 18 U.S.C. 793, 794 or 798; section 4(b) of the Internal Security... International Emergency Economic Powers Act (50 U.S.C. 1701, et seq. (2006 & Supp. IV 2010)). I have received.... Obtain from the Denied Person in the United States any item subject to the Regulations with knowledge or...

  1. 78 FR 21344 - In the Matter of: Andro Telemi, a/k/a Andre Telimi, a/k/a Andre Telemi; 8868 Bluffdale Drive, La...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-10

    ... Economic Powers Act (50 U.S.C. 1701-1706); 18 U.S.C. 793, 794 or 798; section 4(b) of the Internal Security... Emergency Economic Powers Act (50 U.S.C. 1701, et seq. (2006 & Supp. IV 2010)). I have received notice of... United States any item subject to the Regulations with knowledge or reason to know that the item will be...

  2. Naval Expeditionary Logistics Support Group, Training and Evaluation Unit: An Analysis of Current Operations While Searching for Training Efficiencies

    DTIC Science & Technology

    2009-12-01

    of-the-art-classrooms and virtual reality rooms for small arms training. The outlying operational training areas are spread across Cheatham Annex...Movement, and Integration RFM Ready for Mobilization RFT Ready for Tasking SME Subject Matter Expert SWOT Strengths, Weaknesses, Opportunities...document shows that the position is filled (1.0 qualified) but the reality is that the individual is not fully qualified for the required billet (0

  3. 42 CFR 1008.5 - Matters subject to advisory opinions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 5 2011-10-01 2011-10-01 false Matters subject to advisory opinions. 1008.5... SERVICES OIG AUTHORITIES ADVISORY OPINIONS BY THE OIG General Provisions § 1008.5 Matters subject to...) What constitutes prohibited remuneration within the meaning of section 1128B(b) of the Act; (2) Whether...

  4. 76 FR 74691 - Import Restrictions Imposed on Certain Archaeological and Ethnological Material From Greece

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-01

    ... Statuary--Subject matter is varied and includes human and animal figures, human body parts, groups of..., including fragments of statues. Subject matter includes human and animal figures and groups of figures in... marble and other stone. Subject matter includes human and animal figures and groups of figures in the...

  5. 76 FR 2573 - Technical Corrections: Matters Subject to Protest and Various Protest Time Limits

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-14

    ... 174 [CBP Dec. 11-02] Technical Corrections: Matters Subject to Protest and Various Protest Time Limits..., in pertinent part, the types of matters subject to protest, the time required for allowing or denying an application for further review of a protest, and various other protest time limits. This document...

  6. Designing and Developing Technical Curriculum: Finding the Right Subject Matter Expert

    ERIC Educational Resources Information Center

    Mattoon, Joseph Sterling

    2005-01-01

    Subject matter experts play an essential role in technical curriculum development by providing accurate and up-to-date information that matches education, training, and workforce needs. The Subject Matter Expert (SME) COMlist is proposed as a tool that enables instructional developers to evaluate an SME's capability and suitability to support…

  7. The Use of Language in Understanding Subject Matter

    ERIC Educational Resources Information Center

    Svensson, Lennart; Anderberg, Elsie; Alvegard, Christer; Johansson, Thorsten

    2009-01-01

    Empirical results show that frequently the meaning of expressions used by students in expressing their understanding of subject matter does not correspond to the meaning of those expressions in the subject matter theory that the students are expected to learn. There is also often a lack of identity of meaning between the same students' use of the…

  8. Beyond "Either-Or" Thinking: John Dewey and Confucius on Subject Matter and the Learner

    ERIC Educational Resources Information Center

    Tan, Charlene

    2016-01-01

    This article compares the educational thought of John Dewey and Confucius on the nature of and relationship between subject matter and the learner. There is a common perception in the existing literature and discourse that Dewey advocates child- or learner-centred education whereas Confucius privileges subject matter via textual transmission.…

  9. Wide Area Recovery and Resiliency Program (WARRP) Decon-13 Subject Matter Expert Meeting

    DTIC Science & Technology

    2012-08-14

    Japan, Chernobyl , Goiania Waste Screening Workshop August 14, 2012 Edward A. Tupin Center for Radiological Emergency Response Radiation Protection...Total release -10% - 20% of releases from Chernobyl (37 PBq = 1,000,000 Curies) L~:lCl.~== ~ Wide Ar£>a Contamination ~ MEXT data as of S£>pt£>mber...and longer-tenn interim storage - disposal likely will take more time 2 1 On April 26, 1986, Unit 4 of the Chernobyl Nuclear Power Plant suffered

  10. Proceedings of the NATO Nuclear Human Response Subject Matter Expert Review Meeting, 23-25 June 2008, Albuquerque, New Mexico, United States of America

    DTIC Science & Technology

    2009-08-01

    Radiobiological Research Institute (AFRRI) Mr. Michael Leggeiri, Jr, US Army Medical Research and Material Command Dr. Gene McClellan, Applied Research ...to 6 weeks with the radiation injury alone but is accelerated with other injuries; with other injuries death may occur within 2 weeks ≥ 8.3 Bone...Fluence Burn Surface Area Insult Ranges E. Recommendations/ Next Actions: Based on this meeting, the following additional tasks were recommended: 1

  11. Proceedings of the NATO Radiological Human Response Subject Matter Expert Review Meeting, 26 June 2008, Albuquerque, New Mexico, United States of America

    DTIC Science & Technology

    2009-08-01

    the proposed general casualty estimation process. The next two briefings described the technical details of the development and content of the...Forces Radiobiological Research Institute (AFRRI) Dr. Gene McClellan, Applied Research Associates (ARA) COL John Mercier, AFRRI Dr. Kyle Millage...marrow damage occurs; lethality ranges from LD50/60 to LD99/60; death occurs within 3.5 to 6 weeks with the radiation injury alone but is accelerated

  12. Evaluation of a Proposed Modified F/FB-111 Crew Seat and Restraint System.

    DTIC Science & Technology

    1981-11-01

    each target’s path in the X-Z plane throughout the impact. (See sample plots.) Computing velocities and accelerations was a simple matter in the...until this work unit is retired. The experimental results will eventually be recorded within a permanent data bank at AFAMRL. The sample data plots were... experimental results will eventually be recorded within a permanent data bank at AFAMRL. The sample data plots were selected based on the subject who had the

  13. United States Air Force Research Initiation Program. 1985 Technical Report. Volume 3.

    DTIC Science & Technology

    1987-04-01

    miners exposed to airborne radon (7). Thus the major health effect associated with radon is thought to be production of lung cancers by radon decay...Based Instruction: Effect Dr. Linda J. Buehner of Cognitive Style, Instructional Format, and Subject-Matter Content 160-OMG-085 9 Nonlinear Feedback...Instrumentation 760-OMG-042 16 Investigation of the Effects of Dr. David R. Cochran an Applied Electric Field on the InP Melt 760-OMG-014 17 Below-Melt

  14. Substance use and regional gray matter volume in individuals at high risk of psychosis.

    PubMed

    Stone, James M; Bhattacharyya, Sagnik; Barker, Gareth J; McGuire, Philip K

    2012-02-01

    Individuals with an at risk mental state (ARMS) are at greatly increased risk of developing a psychotic illness. Risk of transition to psychosis is associated with regionally reduced cortical gray matter volume. There has been considerable interest in the interaction between psychosis risk and substance use. In this study we investigate the relationship between alcohol, cannabis and nicotine use with gray matter volume in ARMS subjects and healthy volunteers. Twenty seven ARMS subjects and 27 healthy volunteers took part in the study. All subjects underwent volumetric MRI imaging. The relationship between regional gray matter volume and cannabis use, smoking, and alcohol use in controls and ARMS subjects was analysed using voxel-based morphometry. In any region where a significant relationship with drug was present, data were analysed to determine if there was any group difference in this relationship. Alcohol intake was inversely correlated with gray matter volume in cerebellum, cannabis intake was use was inversely correlated with gray matter volume in prefrontal cortex and tobacco intake was inversely correlated with gray matter volume in left temporal cortex. There were no significant interactions by group in any region. There is no evidence to support the hypothesis of increased susceptibility to harmful effects of drugs and alcohol on regional gray matter in ARMS subjects. However, alcohol, tobacco and cannabis at low to moderate intake may be associated with lower gray matter in both ARMS subjects and healthy volunteers-possibly representing low-level cortical damage or change in neural plasticity. Copyright © 2011 Elsevier B.V. All rights reserved.

  15. 45 CFR 1.2 - Subject matter of Office of the Secretary regulations in parts 1-99.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Subject matter of Office of the Secretary regulations in parts 1-99. 1.2 Section 1.2 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HHS'S REGULATIONS § 1.2 Subject matter of Office of the Secretary regulations in parts 1-99. This...

  16. A cross-sectional and follow-up voxel-based morphometric MRI study in adolescent anorexia nervosa.

    PubMed

    Castro-Fornieles, Josefina; Bargalló, Nuria; Lázaro, Luisa; Andrés, Susana; Falcon, Carles; Plana, Maria Teresa; Junqué, Carme

    2009-01-01

    The objective was to examine whether cerebral volumes are reduced, and in what regions, in adolescents with anorexia nervosa and to study changes after nutritional recovery. Twelve anorexia nervosa (DSM-IV) patients aged 11-17 consecutively admitted to an Eating Disorders Unit were assessed by means of psychopathological scales, neuropsychological battery and voxel-based morphometric (VBM) magnetic resonance imaging at admission and after 7 months' follow-up. Nine control subjects of similar age, gender and estimated intelligence level were also studied. The two groups showed differences in gray matter (F=22.2; p<0.001) and cerebrospinal fluid (CSF) (F=21.2; p<0.001) but not in white matter volumes. In anorexic patients, gray matter volume correlated negatively with the copy time from the Rey Complex Figure Test. In the regional VBM study several temporal and parietal gray matter regions were reduced. During follow-up there was a greater global increase in gray matter (F=10.7; p=0.004) and decrease in CSF (F=22.1; p=0.001) in anorexic patients. The increase in gray matter correlated with a decrease in cortisol (Spearman correlation=-0.73; p=0.017). At follow-up there were no differences in global gray matter (F=2.1; p=0.165), white matter (F=0.02, p=0.965) or CSF (F=1.8; p=0.113) volumes between both groups. There were still some smaller areas, in the right temporal and both supplementary motor area, showing differences between them in the regional VBM study. In conclusion, in adolescent anorexic patients gray matter is more affected than white matter and mainly involves the posterior regions of the brain. Overall gray matter alterations are reversible after nutritional recovery.

  17. Increased white matter metabolic rates in autism spectrum disorder and schizophrenia.

    PubMed

    Mitelman, Serge A; Buchsbaum, Monte S; Young, Derek S; Haznedar, M Mehmet; Hollander, Eric; Shihabuddin, Lina; Hazlett, Erin A; Bralet, Marie-Cecile

    2017-11-22

    Both autism spectrum disorder (ASD) and schizophrenia are often characterized as disorders of white matter integrity. Multimodal investigations have reported elevated metabolic rates, cerebral perfusion and basal activity in various white matter regions in schizophrenia, but none of these functions has previously been studied in ASD. We used 18 fluorodeoxyglucose positron emission tomography to compare white matter metabolic rates in subjects with ASD (n = 25) to those with schizophrenia (n = 41) and healthy controls (n = 55) across a wide range of stereotaxically placed regions-of-interest. Both subjects with ASD and schizophrenia showed increased metabolic rates across the white matter regions assessed, including internal capsule, corpus callosum, and white matter in the frontal and temporal lobes. These increases were more pronounced, more widespread and more asymmetrical in subjects with ASD than in those with schizophrenia. The highest metabolic increases in both disorders were seen in the prefrontal white matter and anterior limb of the internal capsule. Compared to normal controls, differences in gray matter metabolism were less prominent and differences in adjacent white matter metabolism were more prominent in subjects with ASD than in those with schizophrenia. Autism spectrum disorder and schizophrenia are associated with heightened metabolic activity throughout the white matter. Unlike in the gray matter, the vector of white matter metabolic abnormalities appears to be similar in ASD and schizophrenia, may reflect inefficient functional connectivity with compensatory hypermetabolism, and may be a common feature of neurodevelopmental disorders.

  18. Increased PK11195-PET binding in normal-appearing white matter in clinically isolated syndrome

    PubMed Central

    Politis, Marios; Su, Paul; Turkheimer, Federico E.; Malik, Omar; Keihaninejad, Shiva; Wu, Kit; Waldman, Adam; Reynolds, Richard; Nicholas, Richard; Piccini, Paola

    2015-01-01

    The most accurate predictor of the subsequent development of multiple sclerosis in clinically isolated syndrome is the presence of lesions at magnetic resonance imaging. We used in vivo positron emission tomography with 11C-(R)-PK11195, a biomarker of activated microglia, to investigate the normal-appearing white matter and grey matter of subjects with clinically isolated syndrome to explore its role in the development of multiple sclerosis. Eighteen clinically isolated syndrome and eight healthy control subjects were recruited. Baseline assessment included: history, neurological examination, expanded disability status scale, magnetic resonance imaging and PK11195-positron emission tomography scans. All assessments except the PK11195-positron emission tomography scan were repeated over 2 years. SUPERPK methodology was used to measure the binding potential relative to the non-specific volume, BPND. We show a global increase of normal-appearing white matter PK11195 BPND in clinically isolated syndrome subjects compared with healthy controls (P = 0.014). Clinically isolated syndrome subjects with T2 magnetic resonance imaging lesions had higher PK11195 BPND in normal-appearing white matter (P = 0.009) and their normal-appearing white matter PK11195 BPND correlated with the Expanded Disability Status Scale (P = 0.007; r = 0.672). At 2 years those who developed dissemination in space or multiple sclerosis, had higher PK11195 BPND in normal-appearing white matter at baseline (P = 0.007 and P = 0.048, respectively). Central grey matter PK11195 BPND was increased in subjects with clinically isolated syndrome compared to healthy controls but no difference was found in cortical grey matter PK11195 BPND. Microglial activation in clinically isolated syndrome normal-appearing white matter is diffusely increased compared with healthy control subjects and is further increased in those who have magnetic resonance imaging lesions. Furthermore microglial activation in clinically isolated syndrome normal-appearing white matter is also higher in those subjects who developed multiple sclerosis at 2 years. Our finding, if replicated in a larger study, could be of prognostic value and aid early treatment decisions in clinically isolated syndrome. PMID:25416179

  19. Added value of high-b-value (b = 3000 s/mm2) diffusion-weighted imaging at 3 T in relation to fluid-attenuated inversion recovery images for the evaluation of cortical lesions in inflammatory brain diseases.

    PubMed

    Iwashita, Koya; Hirai, Toshinori; Kitajima, Mika; Shigematsu, Yoshinori; Uetani, Hiroyuki; Iryo, Yasuhiko; Azuma, Minako; Hayashida, Eri; Ando, Yukio; Murakami, Ryuji; Yamashita, Yasuyuki

    2013-01-01

    The purpose of this study was to determine how the gray-to-white matter contrast in healthy subjects changes on high-b-value diffusion-weighted imaging (DWI) acquired at 3 T and evaluate whether high-b-value DWI at 3 T is useful for the detection of cortical lesions in inflammatory brain diseases. Ten healthy volunteers underwent DWI at b = 1000, 2000, 3000, 4000, and 5000 s/mm(2) on a 3-T MRI unit. On DW images, 1 radiologist performed region-of-interest measurements of the signal intensity of 8 gray matter structures. The gray-to-white matter contrast ratio (GWCR) was calculated. Ten patients with inflammatory cortical lesions were also included. All patients underwent conventional MRI and DWI at b = 1000 and 3000 s/mm(2). Using a 4-point grading system, 2 radiologists independently assessed the presence of additional information on DW images compared with fluid-attenuated inversion recovery images. Interobserver agreement was assessed by κ statistics. In the healthy subjects, the b value increased as the GWCR decreased in all evaluated gray matter structures. On DW images acquired at b = 3000 s/mm(2), mean GWCR was less than 1.0 in 7 of 8 structures. For both reviewers, DWI at b = 3000 s/mm(2) yielded significantly more additional information than did DWI at b = 1000 s/mm(2) (P < 0.05). Interobserver agreement for DWI at b = 1000 s/mm(2) and b = 3000 s/mm(2) was fair (κ = 0.35) and excellent (κ = 1.0), respectively. At 3-T DWI, the gray-to-white matter contrast in most gray matter structures reverses at b = 3000 s/mm. In the evaluation of cortical lesions in patients with inflammatory brain diseases, 3-T DWI at b = 3000 s/mm was more useful than b = 1000 s/mm(2).

  20. The nature and development of preservice science teachers' conceptions of subject matter and pedagogy

    NASA Astrophysics Data System (ADS)

    Lederman, Norman G.; Gess-Newsome, Julie; Latz, Mark S.

    The purpose of this study was to assess the development and changes in preservice science teachers' subject matter and pedagogy knowledge structures as they proceeded through a professional teacher education program. Twelve secondary preservice science teachers were asked to create representations of their subject matter and pedagogy knowledge structures periodically (four times spanning the entirety of their subject-specific teacher education program) and participate in a videotaped interview concerning the eight knowledge structure representations immediately following student teaching. Qualitative analyses of knowledge structure representations and transcribed interviews within and between subjects were performed by one of the researchers and blindly corroborated by the other two researchers. Initial knowledge structure representations were typically linear and lacked coherence. Both types of knowledge structure representations were highly susceptible to change as a consequence of the act of teaching. Although there was some overlap between subject matter and pedagogy knowledge structures, they were reported to exert separate influences on classroom practice, with the pedagogy knowledge structure having primary influence on instructional decisions. Furthermore, the complexity of one's subject matter structure appeared to be a critical factor in determining whether the structure directly influences classroom practice.Received: 5 February 1993; Revised: 28 July 1993;

  1. Cortical magnetic resonance imaging findings in familial pediatric bipolar disorder.

    PubMed

    Chang, Kiki; Barnea-Goraly, Naama; Karchemskiy, Asya; Simeonova, Diana Iorgova; Barnes, Patrick; Ketter, Terence; Reiss, Allan L

    2005-08-01

    Morphometric magnetic resonance imaging (MRI) studies of pediatric bipolar disorder (BD) have not reported on gray matter volumes but have reported increased lateral ventricular size and presence of white matter hyperintensities (WMH). We studied gray matter volume, ventricular-to-brain ratios (VBR), and number of WMH in patients with familial, pediatric BD compared with control subjects. Twenty subjects with BD (aged 14.6 +/- 2.8 years; 4 female) according to the Washington University in St. Louis Kiddie Schedule for Affective Disorders and Schizophrenia, each with a parent with BD, and 20 age-, gender-, and intelligence quotient-matched healthy control subjects (aged 14.1 +/- 2.8 years; 4 female) were scanned at 3 T. Most subjects were taking psychotropic medications. A high-resolution T1-weighted spoiled gradient echo three-dimensional MRI sequence was analyzed by BrainImage for volumetric measurements, and T2-weighted images were read by a neuroradiologist to determine presence of WMH. After covarying for age and total brain volume, there were no significant differences between subjects with BD and control subjects in volume of cerebral (p = .09) or prefrontal gray matter (p = .34). Subjects with BD did not have elevated numbers of WMH or greater VBR when compared with control subjects. Children and adolescents with familial BD do not seem to have decreased cerebral grey matter or increased numbers of WMH, dissimilar to findings in adults with BD. Gray matter decreases and development of WMH might be later sequelae of BD or unique to adult-onset BD.

  2. Fiberprint: A subject fingerprint based on sparse code pooling for white matter fiber analysis.

    PubMed

    Kumar, Kuldeep; Desrosiers, Christian; Siddiqi, Kaleem; Colliot, Olivier; Toews, Matthew

    2017-09-01

    White matter characterization studies use the information provided by diffusion magnetic resonance imaging (dMRI) to draw cross-population inferences. However, the structure, function, and white matter geometry vary across individuals. Here, we propose a subject fingerprint, called Fiberprint, to quantify the individual uniqueness in white matter geometry using fiber trajectories. We learn a sparse coding representation for fiber trajectories by mapping them to a common space defined by a dictionary. A subject fingerprint is then generated by applying a pooling function for each bundle, thus providing a vector of bundle-wise features describing a particular subject's white matter geometry. These features encode unique properties of fiber trajectories, such as their density along prominent bundles. An analysis of data from 861 Human Connectome Project subjects reveals that a fingerprint based on approximately 3000 fiber trajectories can uniquely identify exemplars from the same individual. We also use fingerprints for twin/sibling identification, our observations consistent with the twin data studies of white matter integrity. Our results demonstrate that the proposed Fiberprint can effectively capture the variability in white matter fiber geometry across individuals, using a compact feature vector (dimension of 50), making this framework particularly attractive for handling large datasets. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. Total Force Fitness in units part 1: military demand-resource model.

    PubMed

    Bates, Mark J; Fallesen, Jon J; Huey, Wesley S; Packard, Gary A; Ryan, Diane M; Burke, C Shawn; Smith, David G; Watola, Daniel J; Pinder, Evette D; Yosick, Todd M; Estrada, Armando X; Crepeau, Loring; Bowles, Stephen V

    2013-11-01

    The military unit is a critical center of gravity in the military's efforts to enhance resilience and the health of the force. The purpose of this article is to augment the military's Total Force Fitness (TFF) guidance with a framework of TFF in units. The framework is based on a Military Demand-Resource model that highlights the dynamic interactions across demands, resources, and outcomes. A joint team of subject-matter experts identified key variables representing unit fitness demands, resources, and outcomes. The resulting framework informs and supports leaders, support agencies, and enterprise efforts to strengthen TFF in units by (1) identifying TFF unit variables aligned with current evidence and operational practices, (2) standardizing communication about TFF in units across the Department of Defense enterprise in a variety of military organizational contexts, (3) improving current resources including evidence-based actions for leaders, (4) identifying and addressing of gaps, and (5) directing future research for enhancing TFF in units. These goals are intended to inform and enhance Service efforts to develop Service-specific TFF models, as well as provide the conceptual foundation for a follow-on article about TFF metrics for units. Reprint & Copyright © 2013 Association of Military Surgeons of the U.S.

  4. Production Scheduling of Sequenced Tapes for Printed Circuit Pack Assembly.

    DTIC Science & Technology

    1987-07-09

    detail. L j 6 The subject matter of this thesis is inspired directly from their technical report. The goals of this research are twofold: 1) Test their...The subject matter of the following chapters describes a heuristic approach to another variation of the sequenced tape production scheduling problem...assignment problem, comprise the subject matter of Chapter 5. It is sufficient to note that the three definitions of the term common correspond to the

  5. Gene and genetic diagnostic method patent claims: a comparison under current European and US patent law

    PubMed Central

    Huys, Isabelle; Van Overwalle, Geertrui; Matthijs, Gert

    2011-01-01

    The paper focuses on the fundamental debate that is going on in Europe and the United States about whether genes and genetic diagnostic methods are to be regarded as inventions or subject matter eligible for patent protection, or whether they are discoveries or principles of nature and thus excluded from patentability. The study further explores some possible scenarios of American influences on European patent applications with respect to genetic diagnostic methods. Our analysis points out that patent eligibility for genes and genetic diagnostic methods, as discussed in the United States in the Association of Molecular Pathology versus US Patent and Trademark Office decision, is based on a different reasoning compared with the European Patent Convention. PMID:21654725

  6. Gene and genetic diagnostic method patent claims: a comparison under current European and US patent law.

    PubMed

    Huys, Isabelle; Van Overwalle, Geertrui; Matthijs, Gert

    2011-10-01

    The paper focuses on the fundamental debate that is going on in Europe and the United States about whether genes and genetic diagnostic methods are to be regarded as inventions or subject matter eligible for patent protection, or whether they are discoveries or principles of nature and thus excluded from patentability. The study further explores some possible scenarios of American influences on European patent applications with respect to genetic diagnostic methods. Our analysis points out that patent eligibility for genes and genetic diagnostic methods, as discussed in the United States in the Association of Molecular Pathology versus US Patent and Trademark Office decision, is based on a different reasoning compared with the European Patent Convention.

  7. Instructional Design and Online Learning: A Quality Assurance Study

    ERIC Educational Resources Information Center

    Monroe, Rose M.

    2011-01-01

    The purpose of this study was to investigate the difference in the evaluations of online course quality using the Quality Matters model among four groups of reviewers: instructional designers, faculty with subject-matter expertise, peer faculty with no subject-matter expertise, and administrators. A causal-comparative design was utilized to…

  8. Increased PK11195-PET binding in normal-appearing white matter in clinically isolated syndrome.

    PubMed

    Giannetti, Paolo; Politis, Marios; Su, Paul; Turkheimer, Federico E; Malik, Omar; Keihaninejad, Shiva; Wu, Kit; Waldman, Adam; Reynolds, Richard; Nicholas, Richard; Piccini, Paola

    2015-01-01

    The most accurate predictor of the subsequent development of multiple sclerosis in clinically isolated syndrome is the presence of lesions at magnetic resonance imaging. We used in vivo positron emission tomography with (11)C-(R)-PK11195, a biomarker of activated microglia, to investigate the normal-appearing white matter and grey matter of subjects with clinically isolated syndrome to explore its role in the development of multiple sclerosis. Eighteen clinically isolated syndrome and eight healthy control subjects were recruited. Baseline assessment included: history, neurological examination, expanded disability status scale, magnetic resonance imaging and PK11195-positron emission tomography scans. All assessments except the PK11195-positron emission tomography scan were repeated over 2 years. SUPERPK methodology was used to measure the binding potential relative to the non-specific volume, BPND. We show a global increase of normal-appearing white matter PK11195 BPND in clinically isolated syndrome subjects compared with healthy controls (P = 0.014). Clinically isolated syndrome subjects with T2 magnetic resonance imaging lesions had higher PK11195 BPND in normal-appearing white matter (P = 0.009) and their normal-appearing white matter PK11195 BPND correlated with the Expanded Disability Status Scale (P = 0.007; r = 0.672). At 2 years those who developed dissemination in space or multiple sclerosis, had higher PK11195 BPND in normal-appearing white matter at baseline (P = 0.007 and P = 0.048, respectively). Central grey matter PK11195 BPND was increased in subjects with clinically isolated syndrome compared to healthy controls but no difference was found in cortical grey matter PK11195 BPND. Microglial activation in clinically isolated syndrome normal-appearing white matter is diffusely increased compared with healthy control subjects and is further increased in those who have magnetic resonance imaging lesions. Furthermore microglial activation in clinically isolated syndrome normal-appearing white matter is also higher in those subjects who developed multiple sclerosis at 2 years. Our finding, if replicated in a larger study, could be of prognostic value and aid early treatment decisions in clinically isolated syndrome. © The Author (2014). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  9. One Health in food safety and security education: Subject matter outline for a curricular framework.

    PubMed

    Angelos, John A; Arens, Amanda L; Johnson, Heather A; Cadriel, Jessica L; Osburn, Bennie I

    2017-06-01

    Educating students in the range of subjects encompassing food safety and security as approached from a One Health perspective requires consideration of a variety of different disciplines and the interrelationships among disciplines. The Western Institute for Food Safety and Security developed a subject matter outline to accompany a previously published One Health in food safety and security curricular framework. The subject matter covered in this outline encompasses a variety of topics and disciplines related to food safety and security including effects of food production on the environment. This subject matter outline should help guide curriculum development and education in One Health in food safety and security and provides useful information for educators, researchers, students, and public policy-makers facing the inherent challenges of maintaining and/or developing safe and secure food supplies without destroying Earth's natural resources.

  10. A Study to Design a Functional Patient Health Education Program for Implementation at the United States Army Medical Department Activity, Fort Benning, Georgia

    DTIC Science & Technology

    1980-08-01

    Inventory of Innovations Required in Outpatient Care Delivery Mechanisms. 6APC Model #14: 2-3. 1k. 7 Elizabeth A. Lee, "Health Education," Hospitals...within Appendix K. A complete inventory of clinical settings was then assembled, and utilizing a random numbers table, gross numbers of patient...are aimed at most of the major seg- I. ments of the patient beneficiary population, while addressing a well balanced inventory of subject matter. In

  11. Insight on AV-45 binding in white and grey matter from histogram analysis: a study on early Alzheimer's disease patients and healthy subjects

    PubMed Central

    Nemmi, Federico; Saint-Aubert, Laure; Adel, Djilali; Salabert, Anne-Sophie; Pariente, Jérémie; Barbeau, Emmanuel; Payoux, Pierre; Péran, Patrice

    2014-01-01

    Purpose AV-45 amyloid biomarker is known to show uptake in white matter in patients with Alzheimer’s disease (AD) but also in healthy population. This binding; thought to be of a non-specific lipophilic nature has not yet been investigated. The aim of this study was to determine the differential pattern of AV-45 binding in healthy and pathological populations in white matter. Methods We recruited 24 patients presenting with AD at early stage and 17 matched, healthy subjects. We used an optimized PET-MRI registration method and an approach based on intensity histogram using several indexes. We compared the results of the intensity histogram analyses with a more canonical approach based on target-to-cerebellum Standard Uptake Value (SUVr) in white and grey matters using MANOVA and discriminant analyses. A cluster analysis on white and grey matter histograms was also performed. Results White matter histogram analysis revealed significant differences between AD and healthy subjects, which were not revealed by SUVr analysis. However, white matter histograms was not decisive to discriminate groups, and indexes based on grey matter only showed better discriminative power than SUVr. The cluster analysis divided our sample in two clusters, showing different uptakes in grey but also in white matter. Conclusion These results demonstrate that AV-45 binding in white matter conveys subtle information not detectable using SUVr approach. Although it is not better than standard SUVr to discriminate AD patients from healthy subjects, this information could reveal white matter modifications. PMID:24573658

  12. Cortex Parcellation Associated Whole White Matter Parcellation in Individual Subjects.

    PubMed

    Schiffler, Patrick; Tenberge, Jan-Gerd; Wiendl, Heinz; Meuth, Sven G

    2017-01-01

    The investigation of specific white matter areas is a growing field in neurological research and is typically achieved through the use of atlases. However, the definition of anatomically based regions remains challenging for the white matter and thus hinders region-specific analysis in individual subjects. In this article, we focus on creating a whole white matter parcellation method for individual subjects where these areas can be associated to cortex regions. This is done by combining cortex parcellation and fiber tracking data. By tracking fibers out of each cortex region and labeling the fibers according to their origin, we populate a candidate image. We then derive the white matter parcellation by classifying each white matter voxel according to the distribution of labels in the corresponding voxel from the candidate image. The parcellation of the white matter with the presented method is highly reliable and is not as dependent on registration as with white matter atlases. This method allows for the parcellation of the whole white matter into individual cortex region associated areas and, therefore, associates white matter alterations to cortex regions. In addition, we compare the results from the presented method to existing atlases. The areas generated by the presented method are not as sharply defined as the areas in most existing atlases; however, they are computed directly in the DWI space of the subject and, therefore, do not suffer from distortion caused by registration. The presented approach might be a promising tool for clinical and basic research to investigate modalities or system specific micro structural alterations of white matter areas in a quantitative manner.

  13. Cortex Parcellation Associated Whole White Matter Parcellation in Individual Subjects

    PubMed Central

    Schiffler, Patrick; Tenberge, Jan-Gerd; Wiendl, Heinz; Meuth, Sven G.

    2017-01-01

    The investigation of specific white matter areas is a growing field in neurological research and is typically achieved through the use of atlases. However, the definition of anatomically based regions remains challenging for the white matter and thus hinders region-specific analysis in individual subjects. In this article, we focus on creating a whole white matter parcellation method for individual subjects where these areas can be associated to cortex regions. This is done by combining cortex parcellation and fiber tracking data. By tracking fibers out of each cortex region and labeling the fibers according to their origin, we populate a candidate image. We then derive the white matter parcellation by classifying each white matter voxel according to the distribution of labels in the corresponding voxel from the candidate image. The parcellation of the white matter with the presented method is highly reliable and is not as dependent on registration as with white matter atlases. This method allows for the parcellation of the whole white matter into individual cortex region associated areas and, therefore, associates white matter alterations to cortex regions. In addition, we compare the results from the presented method to existing atlases. The areas generated by the presented method are not as sharply defined as the areas in most existing atlases; however, they are computed directly in the DWI space of the subject and, therefore, do not suffer from distortion caused by registration. The presented approach might be a promising tool for clinical and basic research to investigate modalities or system specific micro structural alterations of white matter areas in a quantitative manner. PMID:28729829

  14. 76 FR 15349 - National Science Board; Sunshine Act Meetings; Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-21

    ... National Science Board business and other matters specified, as follows: DATE, TIME AND SUBJECT MATTER..., 2011 8:30 National Science Foundation Perspective 8:45-10:30 Session V: Policy Issues 10:45-11 Public... schedule updates (time, place, subject matter or status of meeting) may be found at http://www.nsf.gov/nsb...

  15. Voxel-based morphometry in autopsy proven PSP and CBD.

    PubMed

    Josephs, Keith A; Whitwell, Jennifer L; Dickson, Dennis W; Boeve, Bradley F; Knopman, David S; Petersen, Ronald C; Parisi, Joseph E; Jack, Clifford R

    2008-02-01

    The aim of this study was to compare the patterns of grey and white matter atrophy on MRI in autopsy confirmed progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD), and to determine whether the patterns vary depending on the clinical syndrome. Voxel-based morphometry was used to compare patterns of atrophy in 13 PSP and 11 CBD subjects and 24 controls. PSP and CBD subjects were also subdivided into those with a dominant dementia or extrapyramidal syndrome. PSP subjects showed brainstem atrophy with involvement of the cortex and underlying white matter. Frontoparietal grey and subcortical grey matter atrophy occurred in CBD. When subdivided, PSP subjects with an extrapyramidal syndrome had more brainstem atrophy and less cortical atrophy than CBD subjects with an extrapyramidal syndrome. PSP subjects with a dementia syndrome had more subcortical white matter atrophy than CBD subjects with a dementia syndrome. These results show regional differences between PSP and CBD that are useful in predicting the underlying pathology, and help to shed light on the in vivo distribution of regional atrophy in PSP and CBD.

  16. Examining elementary teachers' knowledge and instruction of scientific explanations for fostering children's explanations in science

    NASA Astrophysics Data System (ADS)

    Wiebke, Heidi Lynn

    This study employed an embedded mixed methods multi-case study design (Creswell, 2014) with six early childhood (grades K-2) teachers to examine a) what changes occurred to their subject matter knowledge (SMK) and pedagogical content knowledge (PCK) for teaching scientific explanations while participating in a professional development program, b) how they planned for and implemented scientific explanation instruction within a teacher developed unit on properties of matter, and c) what affordances their instruction of scientific explanations had on fostering their students' abilities to generate explanations in science. Several quantitative and qualitative measures were collected and analyzed in accordance to this studies conceptual framework, which consisted of ten instructional practices teachers should consider assimilating or accommodating into their knowledge base (i.e., SMK & PCK) for teaching scientific explanations. Results of this study indicate there was little to no positive change in the teachers' substantive and syntactic SMK. However, all six teachers did make significant changes to all five components of their PCK for teaching explanations in science. While planning for scientific explanation instruction, all six teachers' contributed some ideas for how to incorporate seven of the ten instructional practices for scientific explanations within the properties of matter unit they co-developed. When enacting the unit, the six teachers' employed seven to nine of the instructional practices to varying levels of effectiveness, as measured by researcher developed rubrics. Given the six teachers' scientific explanation instruction, many students did show improvement in their ability to formulate a scientific explanation, particularly their ability to provide multiple pieces of evidence. Implications for professional developers, teacher educators, researchers, policy makers, and elementary teachers regarding how to prepare teachers for and support students' construction of scientific explanations are discussed.

  17. Developing a Democratic View of Academic Subject Matters: John Dewey, William Chandler Bagley, and Boyd Henry Bode

    ERIC Educational Resources Information Center

    Watras, Joseph

    2012-01-01

    In the first half of the twentieth century, the ideal of democracy influenced the conceptions people had of the academic subject matters. A common criticism was that abstract academic subjects served aristocratic societies. Although most theorists considered the academic subjects to be important, they had differing views on the conception of…

  18. "That Hurts!": Humor and Sadomasochism in "Lolita."

    ERIC Educational Resources Information Center

    Bick, Ilsa J.

    1994-01-01

    States that humor is dependent on individual perspective, and that the subject matter of "Lolita" (1962), which concerns child abuse and molestation, is difficult to treat with humor. Argues that despite its subject, "Lolita" continues to be funny. Concludes that viewers know the subject matter is not funny, but while watching,…

  19. Major advances in extension education programs in dairy production.

    PubMed

    Chase, L E; Ely, L O; Hutjens, M F

    2006-04-01

    The dairy industry has seen structural changes in the last 25 yr that have an impact on extension programming. The number of cows in the United States has decreased by 17%, whereas the number of dairy farms has decreased by 74%. The average milk production per cow has increased from 5,394 to 8,599 kg/lactation. Even though there are fewer farms, dairy farm managers are asking for more specific and targeted information. The extension resources available have also decreased during this period. Because of these changes, shifts have taken place in extension programming and staffing. A key change has been a shift to subject matter-targeted programs and workshops. Extension has also incorporated and expanded use of the Internet. Discussion groups, subject matter courses, and searchable databases are examples of Internet use. There will be continuing shifts in the demographics of the US dairy industry that will influence future extension efforts. It is also probable that fewer extension professionals will be available to provide programming due to changes in funding sources at national, state, and local levels. Future shifts in extension programming will be needed to provide the information needs of the industry with a smaller number of extension workers.

  20. Statistical model selection for better prediction and discovering science mechanisms that affect reliability

    DOE PAGES

    Anderson-Cook, Christine M.; Morzinski, Jerome; Blecker, Kenneth D.

    2015-08-19

    Understanding the impact of production, environmental exposure and age characteristics on the reliability of a population is frequently based on underlying science and empirical assessment. When there is incomplete science to prescribe which inputs should be included in a model of reliability to predict future trends, statistical model/variable selection techniques can be leveraged on a stockpile or population of units to improve reliability predictions as well as suggest new mechanisms affecting reliability to explore. We describe a five-step process for exploring relationships between available summaries of age, usage and environmental exposure and reliability. The process involves first identifying potential candidatemore » inputs, then second organizing data for the analysis. Third, a variety of models with different combinations of the inputs are estimated, and fourth, flexible metrics are used to compare them. As a result, plots of the predicted relationships are examined to distill leading model contenders into a prioritized list for subject matter experts to understand and compare. The complexity of the model, quality of prediction and cost of future data collection are all factors to be considered by the subject matter experts when selecting a final model.« less

  1. Cardiac and Carotid Markers Link With Accelerated Brain Atrophy: The AGES-Reykjavik Study (Age, Gene/Environment Susceptibility-Reykjavik).

    PubMed

    Sabayan, Behnam; van Buchem, Mark A; Sigurdsson, Sigurdur; Zhang, Qian; Meirelles, Osorio; Harris, Tamara B; Gudnason, Vilmundur; Arai, Andrew E; Launer, Lenore J

    2016-11-01

    Pathologies in the heart-brain axis might, independently or in combination, accelerate the process of brain parenchymal loss. We aimed to investigate the association of serum N-terminal brain natriuretic peptide (NT-proBNP), as a marker of cardiac dysfunction, and carotid intima media thickness (CIMT), as a marker of carotid atherosclerosis burden, with structural brain changes. In the longitudinal population-based AGES-Reykjavik study (Age, Gene/Environment Susceptibility-Reykjavik), we included 2430 subjects (mean age, 74.6 years; 41.4% men) with baseline data on NT-proBNP and CITM (assessed by ultrasound imaging). Participants underwent a high-resolution brain magnetic resonance imaging at baseline and 5 years later to assess total brain (TBV), gray matter, and white matter volumes. Each unit higher log-transformed NT-proBNP was associated with 3.6 mL (95% confidence interval [CI], -6.0 to -1.1) decline in TBV and 3.5 mL (95% CI, -5.7 to -1.3) decline in gray matter volume. Likewise, each millimeter higher CIMT was associated with 10.8 mL (95% CI, -17.3 to -4.2) decline in TBV and 8.6 mL (95% CI, -14.4 to -2.8) decline in gray matter volume. There was no association between NT-proBNP and CIMT and changes in white matter volume. Compared with participants with low NT-proBNP and CIMT, participants with both high NT-proBNP and CIMT had 3.8 mL (95% CI, -6.0 to -1.6) greater decline in their TBV and 4 mL (95% CI, -6.0 to -2.0) greater decline in GMW. These associations were independent of sociodemographic and cardiovascular factors. Older subjects with both cardiac dysfunction and carotid atherosclerosis are at an increased risk for brain parenchymal loss. Accumulated pathologies in the heart-brain axis might accelerate brain atrophy. © 2016 American Heart Association, Inc.

  2. Effect of visual experience on structural organization of the human brain: a voxel based morphometric study using DARTEL.

    PubMed

    Modi, Shilpi; Bhattacharya, Manisha; Singh, Namita; Tripathi, Rajendra Prasad; Khushu, Subash

    2012-10-01

    To investigate structural reorganization in the brain with differential visual experience using Voxel-Based Morphometry with Diffeomorphic Anatomic Registration Through Exponentiated Lie algebra algorithm (DARTEL) approach. High resolution structural MR images were taken in fifteen normal sighted healthy controls, thirteen totally blind subjects and six partial blind subjects. The analysis was carried out using SPM8 software on MATLAB 7.6.0 platform. VBM study revealed gray matter volume atrophy in the cerebellum and left inferior parietal cortex in total blind subjects and in left inferior parietal cortex, right caudate nucleus, and left primary visual cortex in partial blind subjects as compared to controls. White matter volume loss was found in calcarine gyrus in total blind subjects and Thlamus-somatosensory region in partially blind subjects as compared to controls. Besides, an increase in Gray Matter volume was also found in left middle occipital and middle frontal gyrus and right entorhinal cortex, and an increase in White Matter volume was found in superior frontal gyrus, left middle temporal gyrus and right Heschl's gyrus in totally blind subjects as compared to controls. Comparison between total and partial blind subjects revealed a greater Gray Matter volume in left cerebellum of partial blinds and left Brodmann area 18 of total blind subjects. Results suggest that, loss of vision at an early age can induce significant structural reorganization on account of the loss of visual input. These plastic changes are different in early onset of total blindness as compared to partial blindness. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  3. Conservation: Where we stand: Review of Water, land, and people

    USGS Publications Warehouse

    Leopold, Luna Bergere

    1951-01-01

    A distinguished conservationist, just returned from more than a year in those Pacific islands held in trust by the United States, reports that representatives of the government there are nearly completely concerned with the maintenance of an administrative organization. Actual advances in matters of land use, of maintaining the material and mental welfare of the native population, and the preservation of the most interesting remnants of untouched habitat, are just never made.Any such oversimplification is, of course, subject to error in detail, but it nevertheless stands as a touchstone to where we stand in conservation. In much more guarded phrases, and with considerable supporting data, Bernard Frank and Anthony Netboy say much the same thing about governmental conservation in the United States in their recently published Water, Land, and People.

  4. Experiential Learning of Electronics Subject Matter in Middle School Robotics Courses

    ERIC Educational Resources Information Center

    Rihtaršic, David; Avsec, Stanislav; Kocijancic, Slavko

    2016-01-01

    The purpose of this paper is to investigate whether the experiential learning of electronics subject matter is effective in the middle school open learning of robotics. Electronics is often ignored in robotics courses. Since robotics courses are typically comprised of computer-related subjects, and mechanical and electrical engineering, these…

  5. The Influence of Subject Matter Expertise on Pedagogical Content Knowledge.

    ERIC Educational Resources Information Center

    Manross, Dean; And Others

    This study investigated the role of subject matter expertise on the pedagogical content knowledge of physical education teachers. Data were collected through multiple interviews on 10 teachers with expertise in at least one physical education subject area. Each teacher was interviewed four times, with each interview lasting approximately 1 hour.…

  6. Religion and family planning.

    PubMed

    Pinter, Bojana; Hakim, Marwan; Seidman, Daniel S; Kubba, Ali; Kishen, Meera; Di Carlo, Costantino

    2016-12-01

    Religion is embedded in the culture of all societies. It influences matters of morality, ideology and decision making, which concern every human being at some point in their life. Although the different religions often lack a united view on matters such contraception and abortion, there is sometimes some dogmatic overlap when general religious principles are subject to the influence of local customs. Immigration and population flow add further complexities to societal views on reproductive issues. For example, present day Europe has recently faced a dramatic increase in refugee influx, which raises questions about the health care of immigrants and the effects of cultural and religious differences on reproductive health. Religious beliefs on family planning in, for example, Christianity, Judaism, Islam and Hinduism have grown from different backgrounds and perspectives. Understanding these differences may result in more culturally competent delivery of care by health care providers. This paper presents the teachings of the most widespread religions in Europe with regard to contraception and reproduction.

  7. Baseball Bats and Chocolate Chip Cookies: The Judicial Treatment of DNA in the Myriad Genetics Litigation

    PubMed Central

    Binnie, Ian; Park-Thompson, Vanessa

    2015-01-01

    In June 2013, the U.S. Supreme Court rendered a controversial ruling that naturally occurring DNA segments are “products of nature” and therefore not patentable subject matter. At this intersection between science and law, in litigation of crucial importance to patients, science, and multibillion-dollar biotech enterprises, the appellate judges sidestepped genetics and engaged in a war of metaphors from diamonds to chocolate chip cookies. This case is not an outlier. Apprehensive judges and juries in both Canada and the United States find many convenient excuses to avoid coming to grips with the underlying science in patent cases. But this is simply not acceptable. Legal rulings must be, and must seem to be, well grounded, as a matter of both law and science. The legitimacy of court decisions in the eyes of the stakeholders and the broader public depends on it. PMID:25524722

  8. Executive dysfunctions in migraine with and without aura: what is the role of white matter lesions?

    PubMed

    Le Pira, Francesco; Reggio, Ester; Quattrocchi, Graziella; Sanfilippo, Cristina; Maci, Tiziana; Cavallaro, Tiziana; Zappia, Mario

    2014-01-01

    Executive dysfunctions and white matter lesions on magnetic resonance imaging have been reported in migraine. The aim of this study was to determine whether any correlation between these 2 variables exists. Forty-four subjects affected by migraine with or without aura were compared with 16 healthy subjects. A battery of neuropsychological tests assessing executive functions was administered to all subjects. Number and total volume of white matter lesions were assessed in the whole brain and in the frontal lobe. The performances of both groups of migraineurs, with and without aura, were significantly worse when compared with controls on Boston Scanning Test. Moreover, we found lower performances compared with controls respectively on Frontal Assessment Battery in patients with migraine with aura and on Controlled Oral Word Association Test in patients with migraine without aura. Nineteen patients (43.2%) and one control subject (6.2%) had white matter lesions. We did not find any significant correlation between white matter lesions load and neuropsychological performances. On the basis of our results, white matter lesions load on magnetic resonance imaging do not seem to contribute to neuropsychological performances deficit in migraineurs. © 2013 American Headache Society.

  9. Gray matter and white matter abnormalities in online game addiction.

    PubMed

    Weng, Chuan-Bo; Qian, Ruo-Bing; Fu, Xian-Ming; Lin, Bin; Han, Xiao-Peng; Niu, Chao-Shi; Wang, Ye-Han

    2013-08-01

    Online game addiction (OGA) has attracted greater attention as a serious public mental health issue. However, there are only a few brain magnetic resonance imaging studies on brain structure about OGA. In the current study, we used voxel-based morphometry (VBM) analysis and tract-based spatial statistics (TBSS) to investigate the microstructural changes in OGA and assessed the relationship between these morphology changes and the Young's Internet Addiction Scale (YIAS) scores within the OGA group. Compared with healthy subjects, OGA individuals showed significant gray matter atrophy in the right orbitofrontal cortex, bilateral insula, and right supplementary motor area. According to TBSS analysis, OGA subjects had significantly reduced FA in the right genu of corpus callosum, bilateral frontal lobe white matter, and right external capsule. Gray matter volumes (GMV) of the right orbitofrontal cortex, bilateral insula and FA values of the right external capsule were significantly positively correlated with the YIAS scores in the OGA subjects. Our findings suggested that microstructure abnormalities of gray and white matter were present in OGA subjects. This finding may provide more insights into the understanding of the underlying neural mechanisms of OGA. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  10. A Bayesian Machine Learning Model for Estimating Building Occupancy from Open Source Data

    DOE PAGES

    Stewart, Robert N.; Urban, Marie L.; Duchscherer, Samantha E.; ...

    2016-01-01

    Understanding building occupancy is critical to a wide array of applications including natural hazards loss analysis, green building technologies, and population distribution modeling. Due to the expense of directly monitoring buildings, scientists rely in addition on a wide and disparate array of ancillary and open source information including subject matter expertise, survey data, and remote sensing information. These data are fused using data harmonization methods which refer to a loose collection of formal and informal techniques for fusing data together to create viable content for building occupancy estimation. In this paper, we add to the current state of the artmore » by introducing the Population Data Tables (PDT), a Bayesian based informatics system for systematically arranging data and harmonization techniques into a consistent, transparent, knowledge learning framework that retains in the final estimation uncertainty emerging from data, expert judgment, and model parameterization. PDT probabilistically estimates ambient occupancy in units of people/1000ft2 for over 50 building types at the national and sub-national level with the goal of providing global coverage. The challenge of global coverage led to the development of an interdisciplinary geospatial informatics system tool that provides the framework for capturing, storing, and managing open source data, handling subject matter expertise, carrying out Bayesian analytics as well as visualizing and exporting occupancy estimation results. We present the PDT project, situate the work within the larger community, and report on the progress of this multi-year project.Understanding building occupancy is critical to a wide array of applications including natural hazards loss analysis, green building technologies, and population distribution modeling. Due to the expense of directly monitoring buildings, scientists rely in addition on a wide and disparate array of ancillary and open source information including subject matter expertise, survey data, and remote sensing information. These data are fused using data harmonization methods which refer to a loose collection of formal and informal techniques for fusing data together to create viable content for building occupancy estimation. In this paper, we add to the current state of the art by introducing the Population Data Tables (PDT), a Bayesian model and informatics system for systematically arranging data and harmonization techniques into a consistent, transparent, knowledge learning framework that retains in the final estimation uncertainty emerging from data, expert judgment, and model parameterization. PDT probabilistically estimates ambient occupancy in units of people/1000 ft 2 for over 50 building types at the national and sub-national level with the goal of providing global coverage. The challenge of global coverage led to the development of an interdisciplinary geospatial informatics system tool that provides the framework for capturing, storing, and managing open source data, handling subject matter expertise, carrying out Bayesian analytics as well as visualizing and exporting occupancy estimation results. We present the PDT project, situate the work within the larger community, and report on the progress of this multi-year project.« less

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stewart, Robert N.; Urban, Marie L.; Duchscherer, Samantha E.

    Understanding building occupancy is critical to a wide array of applications including natural hazards loss analysis, green building technologies, and population distribution modeling. Due to the expense of directly monitoring buildings, scientists rely in addition on a wide and disparate array of ancillary and open source information including subject matter expertise, survey data, and remote sensing information. These data are fused using data harmonization methods which refer to a loose collection of formal and informal techniques for fusing data together to create viable content for building occupancy estimation. In this paper, we add to the current state of the artmore » by introducing the Population Data Tables (PDT), a Bayesian based informatics system for systematically arranging data and harmonization techniques into a consistent, transparent, knowledge learning framework that retains in the final estimation uncertainty emerging from data, expert judgment, and model parameterization. PDT probabilistically estimates ambient occupancy in units of people/1000ft2 for over 50 building types at the national and sub-national level with the goal of providing global coverage. The challenge of global coverage led to the development of an interdisciplinary geospatial informatics system tool that provides the framework for capturing, storing, and managing open source data, handling subject matter expertise, carrying out Bayesian analytics as well as visualizing and exporting occupancy estimation results. We present the PDT project, situate the work within the larger community, and report on the progress of this multi-year project.Understanding building occupancy is critical to a wide array of applications including natural hazards loss analysis, green building technologies, and population distribution modeling. Due to the expense of directly monitoring buildings, scientists rely in addition on a wide and disparate array of ancillary and open source information including subject matter expertise, survey data, and remote sensing information. These data are fused using data harmonization methods which refer to a loose collection of formal and informal techniques for fusing data together to create viable content for building occupancy estimation. In this paper, we add to the current state of the art by introducing the Population Data Tables (PDT), a Bayesian model and informatics system for systematically arranging data and harmonization techniques into a consistent, transparent, knowledge learning framework that retains in the final estimation uncertainty emerging from data, expert judgment, and model parameterization. PDT probabilistically estimates ambient occupancy in units of people/1000 ft 2 for over 50 building types at the national and sub-national level with the goal of providing global coverage. The challenge of global coverage led to the development of an interdisciplinary geospatial informatics system tool that provides the framework for capturing, storing, and managing open source data, handling subject matter expertise, carrying out Bayesian analytics as well as visualizing and exporting occupancy estimation results. We present the PDT project, situate the work within the larger community, and report on the progress of this multi-year project.« less

  12. Subject Matter Expert Workshop to Identify Cybersecurity ...

    EPA Pesticide Factsheets

    Report In recognition of the growing need to better address cyber risk and cyber management, the U.S. Environmental Protection Agency’s (EPA) National Homeland Security Research Center (NHSRC) held a Subject Matter Expert Workshop to Identify Cybersecurity Research Gaps and Needs of the Nation’s Water and Wastewater Systems Sector on March 30th and 31st, 2016, at the Ronald Reagan Building in Washington, D.C. The workshop was designed to create a forum for subject matter experts (SMEs) to exchange ideas and address important cybersecurity challenges facing the water sector.

  13. White matter lesion extension to automatic brain tissue segmentation on MRI.

    PubMed

    de Boer, Renske; Vrooman, Henri A; van der Lijn, Fedde; Vernooij, Meike W; Ikram, M Arfan; van der Lugt, Aad; Breteler, Monique M B; Niessen, Wiro J

    2009-05-01

    A fully automated brain tissue segmentation method is optimized and extended with white matter lesion segmentation. Cerebrospinal fluid (CSF), gray matter (GM) and white matter (WM) are segmented by an atlas-based k-nearest neighbor classifier on multi-modal magnetic resonance imaging data. This classifier is trained by registering brain atlases to the subject. The resulting GM segmentation is used to automatically find a white matter lesion (WML) threshold in a fluid-attenuated inversion recovery scan. False positive lesions are removed by ensuring that the lesions are within the white matter. The method was visually validated on a set of 209 subjects. No segmentation errors were found in 98% of the brain tissue segmentations and 97% of the WML segmentations. A quantitative evaluation using manual segmentations was performed on a subset of 6 subjects for CSF, GM and WM segmentation and an additional 14 for the WML segmentations. The results indicated that the automatic segmentation accuracy is close to the interobserver variability of manual segmentations.

  14. Disrupted white matter integrity in heroin dependence: a controlled study utilizing diffusion tensor imaging.

    PubMed

    Liu, Haihong; Li, Lin; Hao, Yihui; Cao, Dong; Xu, Lin; Rohrbaugh, Robert; Xue, Zhimin; Hao, Wei; Shan, Baoci; Liu, Zhening

    2008-01-01

    Fractional anisotropy (FA) via diffusion tensor imaging (DTI) can quantify the white matter integrity. Exposure to addictive drugs, such as alcohol, cocaine, methamphetamine, marijuana, and nicotine has been shown to alter FA. White matter abnormalities have been shown, but it remains unclear whether the white matter FA is altered in heroin dependence. Utilizing DTI, we investigated the FA difference between heroin-dependent and control subjects by a voxel-based strategy. The FA values of the identified regions were calculated from the FA image of each subject and were correlated with clinical features including months of heroin use, age, education, and dose of methadone. Reduced FA among 16 heroin dependent subjects was located in the bilateral frontal sub-gyral regions, right precentral and left cingulate gyrus. FA in the right frontal sub-gyral was negatively correlated with duration of heroin use. The disrupted white matter integrity in right frontal white matter may occur in continuous heroin abuse.

  15. Association between exercise habits and subcortical gray matter volumes in healthy elderly people: A population-based study in Japan.

    PubMed

    Yamamoto, Mikie; Wada-Isoe, Kenji; Yamashita, Fumio; Nakashita, Satoko; Kishi, Masafumi; Tanaka, Kenichiro; Yamawaki, Mika; Nakashima, Kenji

    2017-06-01

    The relationship between exercise and subcortical gray matter volume is not well understood in the elderly population, although reports indicate that exercise may prevent cortical gray matter atrophy. To elucidate this association in the elderly, we measured subcortical gray matter volume and correlated this with volumes to exercise habits in a community-based cohort study in Japan. Subjects without mild cognitive impairment or dementia (n = 280, 35% male, mean age 73.1 ± 5.9 years) were evaluated using the Mini-Mental State Examination (MMSE), an exercise habit questionnaire, and brain magnetic resonance imaging. Subcortical gray matter volume was compared between groups based on the presence/absence of exercise habits. The MMSE was re-administered 3 years after the baseline examination. Ninety-one subjects (32.5%) reported exercise habits (exercise group), and 189 subjects (67.5%) reported no exercise habits (non-exercise group). Volumetric analysis revealed that the volumes in the exercise group were greater in the left hippocampus (p = 0.042) and bilateral nucleus accumbens (left, p = 0.047; right, p = 0.007) compared to those of the non-exercise group. Among the 195 subjects who received a follow-up MMSE examination, the normalized intra-cranial volumes of the left nucleus accumbens (p = 0.004) and right amygdala (p = 0.014)showed significant association with a decline in the follow-up MMSE score. Subjects with exercise habits show larger subcortical gray matter volumes than subjects without exercise habits in community-dwelling elderly subjects in Japan. Specifically, the volume of the nucleus accumbens correlates with both exercise habits and cognitive preservation.

  16. Mental distress and perceived wealth, justice and freedom across eight countries: The invisible power of the macrosystem

    PubMed Central

    Velten, Julia; Margraf, Jürgen

    2018-01-01

    Health and well-being have been related to macro-level factors such as income, income inequality or socioeconomic status. With regard to the increasing burden of disease due to mental disorders worldwide, the association between the macrosystem and mental distress should be further explored, too. In this context, the subjective evaluation of the macrosystem might play an important role. In the present exploratory study, we assessed symptoms of depression, anxiety and stress as well as perceived wealth, justice and freedom in population-based surveys in Spain, France, Germany, Poland, Russia, Sweden, the United Kingdom and the United States of America (n ≈ 1000 per country). The Swedish sample presented the lowest symptom ratings of depression, anxiety and stress and the highest self-rated health. The results also indicated that the subjective evaluation of the macrosystem matters in respect to mental distress. The complete model, including the control variables country, gender, age and education, and perceived wealth, justice and freedom predicted depression, anxiety and stress symptoms explained 8% of the variance of each symptom cluster. The present results encourage research to consider the macrosystem, and the subjective evaluation of macro-level factors, as a relevant component in biopsychosocial models of mental distress. PMID:29718911

  17. Reference Materials and Subject Matter Knowledge Codes for Airman Knowledge Testing

    DOT National Transportation Integrated Search

    2004-06-08

    The listings of reference materials and subject matter knowledge codes have been : prepared by the Federal Aviation Administration (FAA) to establish specific : references for all knowledge standards. The listings contain reference materials : to be ...

  18. The Challenge in Teaching Biotechnology

    NASA Astrophysics Data System (ADS)

    Steele, F.; Aubusson, P.

    2004-08-01

    Agriculture, industry and medicine are being altered by new biotechnologies. Biotechnology education is important because todays students and citizens will make decisions about the development and application of these new molecular biologies. This article reports an investigation of the teaching of biotechnology in an Australian state, New South Wales (NSW). In NSW few students were electing to answer examination questions related to biotechnology, suggesting that few students were studying the topic. This study looks at why electives relating to biotechnology are chosen or not chosen by students and teachers, with the intention of developing a greater understanding of the requirements for provision of a successful unit of study in this subject. Data was obtained through a survey of secondary science teachers, interviews with teachers and two case studies of the teaching of a biotechnology unit. Teachers reported a range of obstacles to the teaching of biotechnology including the difficulty of the subject matter and a lack of practical work that was suited to the content of the teaching unit. If biotechnology is worth learning in school science, then further research is needed to identify ways to promote the effective teaching of this topic, which teachers regard as important for, and interesting to, students but which most teachers choose not to teach.

  19. 77 FR 12102 - In the Matter of: American United Gold Corporation, AMS Homecare Inc., Aucxis Corp., and CYOP...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-28

    ... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] In the Matter of: American United Gold Corporation, AMS Homecare Inc., Aucxis Corp., and CYOP Systems International Inc.; Order of Suspension of... current and accurate information concerning the securities of American United Gold Corporation because it...

  20. White matter connectivity and Internet gaming disorder

    PubMed Central

    Jeong, Bum Seok; Han, Doug Hyun; Kim, Sun Mi; Lee, Sang Won; Renshaw, Perry F.

    2017-01-01

    Internet use and on-line game play stimulate corticostriatal-limbic circuitry in both healthy subjects and subjects with Internet gaming disorder (IGD). We hypothesized that increased fractional anisotropy (FA) with decreased radial diffusivity (RD) would be observed in IGD subjects, compared with healthy control subjects, and that these white matter indices would be associated with clinical variables including duration of illness and executive function. We screened 181 male patients in order to recruit a large number (n = 58) of IGD subjects without psychiatric co-morbidity as well as 26 male healthy comparison subjects. Multiple diffusion-weighted images were acquired using a 3.0 Tesla magnetic resonance imaging scanner. Tract-based spatial statistics was applied to compare group differences in diffusion tensor imaging (DTI) metrics between IGD and healthy comparison subjects. IGD subjects had increased FA values within forceps minor, right anterior thalamic radiation, right corticospinal tract, right inferior longitudinal fasciculus, right cingulum to hippocampus and right inferior fronto-occipital fasciculus (IFOF) as well as parallel decreases in RD value within forceps minor, right anterior thalamic radiation and IFOF relative to healthy control subjects. In addition, the duration of illness in IGD subjects was positively correlated with the FA values (integrity of white matter fibers) and negatively correlated with RD scores (diffusivity of axonal density) of whole brain white matter. In IGD subjects without psychiatric co-morbidity, our DTI results suggest that increased myelination (increased FA and decreased RD values) in right-sided frontal fiber tracts may be the result of extended game play. PMID:25899390

  1. Evidence for Functional Networks within the Human Brain's White Matter.

    PubMed

    Peer, Michael; Nitzan, Mor; Bick, Atira S; Levin, Netta; Arzy, Shahar

    2017-07-05

    Investigation of the functional macro-scale organization of the human cortex is fundamental in modern neuroscience. Although numerous studies have identified networks of interacting functional modules in the gray-matter, limited research was directed to the functional organization of the white-matter. Recent studies have demonstrated that the white-matter exhibits blood oxygen level-dependent signal fluctuations similar to those of the gray-matter. Here we used these signal fluctuations to investigate whether the white-matter is organized as functional networks by applying a clustering analysis on resting-state functional MRI (RSfMRI) data from white-matter voxels, in 176 subjects (of both sexes). This analysis indicated the existence of 12 symmetrical white-matter functional networks, corresponding to combinations of white-matter tracts identified by diffusion tensor imaging. Six of the networks included interhemispheric commissural bridges traversing the corpus callosum. Signals in white-matter networks correlated with signals from functional gray-matter networks, providing missing knowledge on how these distributed networks communicate across large distances. These findings were replicated in an independent subject group and were corroborated by seed-based analysis in small groups and individual subjects. The identified white-matter functional atlases and analysis codes are available at http://mind.huji.ac.il/white-matter.aspx Our results demonstrate that the white-matter manifests an intrinsic functional organization as interacting networks of functional modules, similarly to the gray-matter, which can be investigated using RSfMRI. The discovery of functional networks within the white-matter may open new avenues of research in cognitive neuroscience and clinical neuropsychiatry. SIGNIFICANCE STATEMENT In recent years, functional MRI (fMRI) has revolutionized all fields of neuroscience, enabling identifications of functional modules and networks in the human brain. However, most fMRI studies ignored a major part of the brain, the white-matter, discarding signals from it as arising from noise. Here we use resting-state fMRI data from 176 subjects to show that signals from the human white-matter contain meaningful information. We identify 12 functional networks composed of interacting long-distance white-matter tracts. Moreover, we show that these networks are highly correlated to resting-state gray-matter networks, highlighting their functional role. Our findings enable reinterpretation of many existing fMRI datasets, and suggest a new way to explore the white-matter role in cognition and its disturbances in neuropsychiatric disorders. Copyright © 2017 the authors 0270-6474/17/376394-14$15.00/0.

  2. Grey matter networks in people at increased familial risk for schizophrenia.

    PubMed

    Tijms, Betty M; Sprooten, Emma; Job, Dominic; Johnstone, Eve C; Owens, David G C; Willshaw, David; Seriès, Peggy; Lawrie, Stephen M

    2015-10-01

    Grey matter brain networks are disrupted in schizophrenia, but it is still unclear at which point during the development of the illness these disruptions arise and whether these can be associated with behavioural predictors of schizophrenia. We investigated if single-subject grey matter networks were disrupted in a sample of people at familial risk of schizophrenia. Single-subject grey matter networks were extracted from structural MRI scans of 144 high risk subjects, 32 recent-onset patients and 36 healthy controls. The following network properties were calculated: size, connectivity density, degree, path length, clustering coefficient, betweenness centrality and small world properties. People at risk of schizophrenia showed decreased path length and clustering in mostly prefrontal and temporal areas. Within the high risk sample, the path length of the posterior cingulate cortex and the betweenness centrality of the left inferior frontal operculum explained 81% of the variance in schizotypal cognitions, which was previously shown to be the strongest behavioural predictor of schizophrenia in the study. In contrast, local grey matter volume measurements explained 48% of variance in schizotypy. The present results suggest that single-subject grey matter networks can quantify behaviourally relevant biological alterations in people at increased risk for schizophrenia before disease onset. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. SIGAR Special Inspector General for Afghanistan Reconstruction

    DTIC Science & Technology

    2017-10-30

    Daniel Fisher, Economic and Social Development Subject Matter Expert Emmett Schneider, Funding Subject Matter Expert Clark Irwin, Lead Writer/Editor...governance, economic development, peace and reconciliation, and security issues. Each working group has a matrix of benchmarks—subject to change—to chart...the U.S. efforts to build the Afghan security forces, improve governance, facilitate economic and social development, and combat the sale and

  4. The Semiotics of Two Speech Styles in Shokleng. Sociolinguistic Working Paper Number 103.

    ERIC Educational Resources Information Center

    Urban, Greg

    Two speech styles, origin-myth telling and ritual wailing, found among the Shokleng Indians of south Brazil are analyzed from the perspective of two specific functions of speech style: (1) for indexing or highlighting the subject matter in certain contexts, and (2) for relating the contexts and subject matters to other contexts and subject matters…

  5. Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia

    PubMed Central

    Chen, Aiqing; Akinyemi, Rufus O.; Hase, Yoshiki; Firbank, Michael J.; Ndung’u, Michael N.; Foster, Vincent; Craggs, Lucy J. L.; Washida, Kazuo; Okamoto, Yoko; Thomas, Alan J.; Polvikoski, Tuomo M.; Allan, Louise M.; Oakley, Arthur E.; O’Brien, John T.; Horsburgh, Karen; Ihara, Masafumi

    2016-01-01

    Abstract White matter hyperintensities as seen on brain T 2 -weighted magnetic resonance imaging are associated with varying degrees of cognitive dysfunction in stroke, cerebral small vessel disease and dementia. The pathophysiological mechanisms within the white matter accounting for cognitive dysfunction remain unclear. With the hypothesis that gliovascular interactions are impaired in subjects with high burdens of white matter hyperintensities, we performed clinicopathological studies in post-stroke survivors, who had exhibited greater frontal white matter hyperintensities volumes that predicted shorter time to dementia onset. Histopathological methods were used to identify substrates in the white matter that would distinguish post-stroke demented from post-stroke non-demented subjects. We focused on the reactive cell marker glial fibrillary acidic protein (GFAP) to study the incidence and location of clasmatodendrosis, a morphological attribute of irreversibly injured astrocytes. In contrast to normal appearing GFAP+ astrocytes, clasmatodendrocytes were swollen and had vacuolated cell bodies. Other markers such as aldehyde dehydrogenase 1 family, member L1 (ALDH1L1) showed cytoplasmic disintegration of the astrocytes. Total GFAP+ cells in both the frontal and temporal white matter were not greater in post-stroke demented versus post-stroke non-demented subjects. However, the percentage of clasmatodendrocytes was increased by >2-fold in subjects with post-stroke demented compared to post-stroke non-demented subjects ( P = 0.026) and by 11-fold in older controls versus young controls ( P < 0.023) in the frontal white matter. High ratios of clasmotodendrocytes to total astrocytes in the frontal white matter were consistent with lower Mini-Mental State Examination and the revised Cambridge Cognition Examination scores in post-stroke demented subjects. Double immunofluorescent staining showed aberrant co-localization of aquaporin 4 (AQP4) in retracted GFAP+ astrocytes with disrupted end-feet juxtaposed to microvessels. To explore whether this was associated with the disrupted gliovascular interactions or blood–brain barrier damage, we assessed the co-localization of GFAP and AQP4 immunoreactivities in post-mortem brains from adult baboons with cerebral hypoperfusive injury, induced by occlusion of three major vessels supplying blood to the brain. Analysis of the frontal white matter in perfused brains from the animals surviving 1–28 days after occlusion revealed that the highest intensity of fibrinogen immunoreactivity was at 14 days. At this survival time point, we also noted strikingly similar redistribution of AQP4 and GFAP+ astrocytes transformed into clasmatodendrocytes. Our findings suggest novel associations between irreversible astrocyte injury and disruption of gliovascular interactions at the blood–brain barrier in the frontal white matter and cognitive impairment in elderly post-stroke survivors. We propose that clasmatodendrosis is another pathological substrate, linked to white matter hyperintensities and frontal white matter changes, which may contribute to post-stroke or small vessel disease dementia. PMID:26667280

  6. Teachers mathematical communication profile in explaining subject matter

    NASA Astrophysics Data System (ADS)

    Umami, Rohmatul; Budayasa, I. Ketut; Suwarsono, St.

    2017-12-01

    This study aimed to see a teachers mathematical communication profile in explaining a subject matter. It is a qualitative research. A high-school junior teacher (i.e., a teacher with 1- to 5-year experience) teaching mathematics at X-Social Class was selected as the subject of this study. The data was collected by observing the teachers mathematical communication in explaining a given material (i.e., the rule of sine) in class and an in-depth interview would be organized respectively. The result showed that the junior teacher explained the subject matter in systematic, complete, fluent, and centered manner. In this case, she began with reminding students on the previous material related to the current material to be learned, informing the current learning objectives, and finally delivering the subject matter. To support her explanation, the teacher also provided some related information, led the students attention into the given material by asking them particular related questions, and did not use any confusing terms. However, the study found that some of high-school teachers still used less appropriate language in explaining materials.

  7. What Do Subject Matter Experts Have to Say about Participating in Education and Outreach?

    NASA Astrophysics Data System (ADS)

    Manning, Colleen; NASA's Universe of Learning Team

    2018-01-01

    NASA’s Universe of Learning partners wish to actively engage with Subject Matter Experts (scientists and engineers) throughout the design, development, and delivery of products, programs, and professional development. In order to ensure these engagement efforts aligned with the needs of Subject Matter Experts, the external evaluators conducted an online survey. The subject pool included the scientists and engineers employed at the partner organizations as well as other scientists and engineers affiliated with NASA’s Astrophysics missions and research programs. This presentation will describe scientists’/engineers’ interest in various types of education/outreach, their availability to participate in education/outreach, factors that would encourage their participation in education/outreach, and the preparation and support they have for participation in education/outreach.

  8. The relationship between brain volume and walking outcomes in older adults with and without diabetic peripheral neuropathy.

    PubMed

    Manor, Brad; Newton, Elizabeth; Abduljalil, Amir; Novak, Vera

    2012-09-01

    Diabetic peripheral neuropathy (DPN) alters walking. Yet, the compensatory role of central locomotor circuits remains unclear. We hypothesized that walking outcomes would be more closely related to regional gray matter volumes in older adults with DPN as compared with nonneuropathic diabetic patients and nondiabetic control subjects. Clinically important outcomes of walking (i.e., speed, stride duration variability, and double support time) were measured in 29 patients with DPN (type 2 diabetes with foot-sole somatosensory impairment), 68 diabetic (DM) patients (type 2 diabetes with intact foot-sole sensation), and 89 control subjects. Global and regional gray matter volumes were calculated from 3 Tesla magnetic resonance imaging. DPN subjects walked more slowly (P = 0.005) with greater stride duration variability (P < 0.001) and longer double support (P < 0.001) as compared with DM and control subjects. Diabetes was associated with less cerebellar gray matter volume (P < 0.001), but global gray matter volume was similar between groups. DPN subjects with lower gray matter volume globally (P < 0.004) and regionally (i.e., cerebellum, right-hemisphere dorsolateral prefrontal cortex, basal ganglia, P < 0.005) walked more slowly with greater stride duration variability and/or longer double support. Each relationship was stronger in DPN than DM subjects. In control subjects, brain volumes did not relate to walking patterns. Strong relationships between brain volumes and walking outcomes were observed in the DPN group and to a lesser extent the DM group, but not in control subjects. Individuals with DPN may be more dependent upon supraspinal elements of the motor control system to regulate several walking outcomes linked to poor health in elderly adults.

  9. The Relationship Between Brain Volume and Walking Outcomes in Older Adults With and Without Diabetic Peripheral Neuropathy

    PubMed Central

    Manor, Brad; Newton, Elizabeth; Abduljalil, Amir; Novak, Vera

    2012-01-01

    OBJECTIVE Diabetic peripheral neuropathy (DPN) alters walking. Yet, the compensatory role of central locomotor circuits remains unclear. We hypothesized that walking outcomes would be more closely related to regional gray matter volumes in older adults with DPN as compared with nonneuropathic diabetic patients and nondiabetic control subjects. RESEARCH DESIGN AND METHODS Clinically important outcomes of walking (i.e., speed, stride duration variability, and double support time) were measured in 29 patients with DPN (type 2 diabetes with foot-sole somatosensory impairment), 68 diabetic (DM) patients (type 2 diabetes with intact foot-sole sensation), and 89 control subjects. Global and regional gray matter volumes were calculated from 3 Tesla magnetic resonance imaging. RESULTS DPN subjects walked more slowly (P = 0.005) with greater stride duration variability (P < 0.001) and longer double support (P < 0.001) as compared with DM and control subjects. Diabetes was associated with less cerebellar gray matter volume (P < 0.001), but global gray matter volume was similar between groups. DPN subjects with lower gray matter volume globally (P < 0.004) and regionally (i.e., cerebellum, right-hemisphere dorsolateral prefrontal cortex, basal ganglia, P < 0.005) walked more slowly with greater stride duration variability and/or longer double support. Each relationship was stronger in DPN than DM subjects. In control subjects, brain volumes did not relate to walking patterns. CONCLUSIONS Strong relationships between brain volumes and walking outcomes were observed in the DPN group and to a lesser extent the DM group, but not in control subjects. Individuals with DPN may be more dependent upon supraspinal elements of the motor control system to regulate several walking outcomes linked to poor health in elderly adults. PMID:22665216

  10. K-Means Subject Matter Expert Refined Topic Model Methodology

    DTIC Science & Technology

    2017-01-01

    Refined Topic Model Methodology Topic Model Estimation via K-Means U.S. Army TRADOC Analysis Center-Monterey 700 Dyer Road...January 2017 K-means Subject Matter Expert Refined Topic Model Methodology Topic Model Estimation via K-Means Theodore T. Allen, Ph.D. Zhenhuan...Matter Expert Refined Topic Model Methodology Topic Model Estimation via K-means 5a. CONTRACT NUMBER W9124N-15-P-0022 5b. GRANT NUMBER 5c

  11. Do Subject Matter Knowledge, and Pedagogical Content Knowledge Constitute the Ideal Gas Law of Science Teaching?

    ERIC Educational Resources Information Center

    Lederman, Norman G.; Gess-Newsome, Julie

    1992-01-01

    Describes Pedagogical Content Knowledge and focuses on the empirical research directly concerned with the relationship between science teachers' subject matter knowledge or structures and actual classroom practice. Concludes there is little evidence that a relationship exists. (PR)

  12. Student nurse-educators' construction of teacher identity from a self-evaluation perspective: A quantitative case study.

    PubMed

    Mukumbang, Ferdinand C; Alindekane, Leka Marcel

    2017-04-01

    The aim of this study was to explore the teacher identity formation dynamics of student nurse-educators about the subject matter, pedagogy and didactics. A case study using descriptive quantitative design was employed. Using a cross-sectional approach, data were collected in 2014 using a self-administered questionnaire. Participants were asked to self-evaluate their teaching competencies on the nursing subject matter, pedagogical expertise and didactical expertise. Using descriptive analysis we determined the central tendencies of the constructs. The descriptive analysis revealed a very small variance (0.0011) and standard deviation (0.04) among the means of the three constructs, which indicates a fair balance in the contribution of the subject matter, pedagogy and didactics towards teacher identity formation. Nursing student-educators can achieve a balanced combination of subject matter expert, pedagogical expert and didactical expert combination during the formation of their teacher identity. This could be indicative of how effective the training programme is in helping the students achieve a balanced teacher identity.

  13. Engaging Students with Subject Matter Experts and Science Content Through Classroom Connection Webinars

    NASA Technical Reports Server (NTRS)

    Graff, P. V.; Rampe, E.; Stefanov, W. L.; Vanderbloemen, L.; Higgins, M.

    2015-01-01

    Connecting students and teachers in classrooms with science, technology, engineering, and mathematics (STEM) experts provides an invaluable opportunity. Subject matter experts can share exciting science and science-related events as well as help to "translate" science being conducted by professionals. The Expedition Earth and Beyond (EEAB) Program, facilitated by the Astromaterials Research and Exploration Science (ARES) Division at the NASA Johnson Space Center, has been providing virtual access to subject matter experts through classroom connection webinars for the last five years. Each year, the reach of these events has grown considerably, especially over the last nine months. These virtual connections not only help engage students with role models, but are also designed to help teachers address concepts and content standards they are required to teach. These events also enable scientists and subject matter experts to help "translate" current science in an engaging and understandable manner while actively involving classrooms in the journey of science and exploration.

  14. PRODUCING HIGH CORN YIELDS.

    ERIC Educational Resources Information Center

    Illinois Univ., Urbana. Coll. of Agriculture.

    RESOURCE MATERIAL ON CORN PRODUCTION FOR HIGH SCHOOL VOCATIONAL AGRICULTURE AND ADULT FARMER CLASSES WAS DESIGNED BY A STATE LEVEL GROUP OF SUBJECT MATTER SPECIALISTS, TEACHER EDUCATORS, SUPERVISORS, AND TEACHERS TO HELP SOLVE PROBLEMS THAT CONFRONT CORN PRODUCERS AT PLANTING TIME. THE SUBJECT MATTER CONCERNS PLANTING TIME, DEPTH, ROW WIDTH,…

  15. ELECTRIC MOTORS FOR FARM USE.

    ERIC Educational Resources Information Center

    Illinois Univ., Urbana. Coll. of Agriculture.

    BETWEEN 2 AND 8 HOURS ARE REQUIRED FOR USE OF THIS TEXTUAL OR REFERENCE MATERIAL ON ELECTRIC MOTORS. IT WAS DEVELOPED BY AN AGRICULTURAL EDUCATION-AGRICULTURAL ENGINEERING SPECIALIST ON THE BASIS OF CONFERENCES WITH SUBJECT MATTER SPECIALISTS, TEACHER EDUCATORS, SUPERVISORS, AND TEACHERS. THE OBJECTIVES AND SUBJECT MATTER CENTER AROUND THE…

  16. Astrocyte pathology in the ventral prefrontal white matter in depression.

    PubMed

    Rajkowska, Grazyna; Legutko, Beata; Moulana, Mohadetheh; Syed, Maryam; Romero, Damian G; Stockmeier, Craig A; Miguel-Hidalgo, Jose Javier

    2018-04-07

    Astrocyte functions in white matter are less well understood than in gray matter. Our recent study of white matter in ventral prefrontal cortex (vPFC) revealed alterations in expression of myelin-related genes in major depressive disorder (MDD). Since white matter astrocytes maintain myelin, we hypothesized that morphometry of these cells will be altered in MDD in the same prefrontal white matter region in which myelin-related genes are altered. White matter adjacent to vPFC was examined in 25 MDD and 21 control subjects. Density and size of GFAP-immunoreactive (-ir) astrocyte cell bodies was measured. The area fraction of GFAP-ir astrocytes (cell bodies + processes) was also estimated. GFAP mRNA expression was determined using qRT-PCR. The density of GFAP-ir astrocytes was also measured in vPFC white matter of rats subjected to chronic unpredictable stress (CUS) and control animals. Fibrous and smooth GFAP-ir astrocytes were distinguished in human white matter. The density of both types of astrocytes was significantly decreased in MDD. Area fraction of GFAP immunoreactivity was significantly decreased in MDD, but mean soma size remained unchanged. Expression of GFAP mRNA was significantly decreased in MDD. In CUS rats there was a significant decrease in astrocyte density in prefrontal white matter. The decrease in density and area fraction of white matter astrocytes and GFAP mRNA in MDD may be linked to myelin pathology previously noted in these subjects. Astrocyte pathology may contribute to axon disturbances in axon integrity reported by neuroimaging studies in MDD and interfere with signal conduction in the white matter. Copyright © 2018. Published by Elsevier Ltd.

  17. The effect of the 4MAT learning model on the achievement and motivation of 7th grade students on the subject of particulate nature of matter and an examination of student opinions on the model

    NASA Astrophysics Data System (ADS)

    Aktas, İdris; Bılgın, İbrahim

    2015-01-01

    Background:Many researchers agree that students, especially primary students, have learning difficulties on the 'Particulate Nature of Matter' unit. One reason for this difficulty is not considering individual differences for teaching science. In 4MAT model learning, environment is arranged according to individual differences. Purpose:The purpose of this study is to examine (1) the effects of the 4MAT learning model on the7th grade students' academic achievement and motivation on the 'Particulate Nature of Matter' unit and (2) identify student opinions on the 4MAT model. Sample:The sample consists of 235 students (115 experimental, 120 control) in Turkey. Design and methods:Experimental groups were instructed with the 4MAT model while control groups were instructed with a traditional method. Achievement Test (AchToM) and Motivation Scale (MotScl) were administered to students as pre- and post-tests. Moreover, the opinions of students in the experimental groups on the 4MAT model were ascertained through open-ended questions after the application. Results:According to independent t-test results, statistical difference in favour of the experimental groups was detected between the post-AchToM (ES = 1.43; p < .0001) and post-MotScl (ES = 0.32; p < .05) scores. According to data obtained from the questionnaire, the application of the 4MAT model increases student motivation and participation in the lesson, lessons are more amusing and enjoyable, and the self-confidence of the students increases. Besides these positive opinions, however, a few students stated that the method took too much time, they were not motivated and it did not help them in understanding the subject. Conclusions:The 4MAT model is more effective than traditional method in terms of increasing achievement and motivation. The model takes all learners into account. Thus, the teacher or educator should use the 4MAT model to ensure all students' learning in their classroom.

  18. Decreased white matter integrity in fronto-occipital fasciculus bundles: relation to visual information processing in alcohol-dependent subjects.

    PubMed

    Bagga, Deepika; Sharma, Aakansha; Kumari, Archana; Kaur, Prabhjot; Bhattacharya, Debajyoti; Garg, Mohan Lal; Khushu, Subash; Singh, Namita

    2014-02-01

    Chronic alcohol abuse is characterized by impaired cognitive abilities with a more severe deficit in visual than in verbal functions. Neuropathologically, it is associated with widespread brain structural compromise marked by gray matter shrinkage, ventricular enlargement, and white matter degradation. The present study sought to increase current understanding of the impairment of visual processing abilities in alcohol-dependent subjects, and its correlation with white matter microstructural alterations, using diffusion tensor imaging (DTI). To that end, a DTI study was carried out on 35 alcohol-dependent subjects and 30 healthy male control subjects. Neuropsychological tests were assessed for visual processing skills and deficits were reported as raw dysfunction scores (rDyS). Reduced FA (fractional anisotropy) and increased MD (mean diffusivity) were observed bilaterally in inferior and superior fronto-occipital fasciculus (FOF) fiber bundles. A significant inverse correlation in rDyS and FA values was observed in these fiber tracts whereas a positive correlation of these scores was found with the MD values. Our results suggest that FOF fiber bundles linking the frontal lobe to occipital lobe might be related to visual processing skills. This is the first report of an alteration of the white matter microstructure of FOF fiber bundles that might have functional consequences for visual processing in alcohol-dependent subjects who exhibit no neurological complications. Copyright © 2014 Elsevier Inc. All rights reserved.

  19. Energy Underground.

    ERIC Educational Resources Information Center

    Wiley, Catherina L.

    2003-01-01

    Describes a unit to study the cycling of matter and energy through speleology using cooperative learning groups. Integrates the topic with zoology, biogeochemistry, paleontology, and meteorology. Includes a sample rubric for a salt block cave presentation, unit outline, and processes for studying matter and energy processes in caves. (Author/KHR)

  20. Examining Language To Capture Scientific Understandings: The Case of the Water Cycle.

    ERIC Educational Resources Information Center

    Varelas, Maria; Pappas, Christine; Barry, Anne; O'Neill, Amy

    2001-01-01

    Presents units that address states of matter and changes of states of matter linked with the water cycle and integrates literacy and science. Discusses the language in science books. Lists characteristics of good science inquiry units. (Contains 11 references.) (ASK)

  1. Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia.

    PubMed

    Chen, Aiqing; Akinyemi, Rufus O; Hase, Yoshiki; Firbank, Michael J; Ndung'u, Michael N; Foster, Vincent; Craggs, Lucy J L; Washida, Kazuo; Okamoto, Yoko; Thomas, Alan J; Polvikoski, Tuomo M; Allan, Louise M; Oakley, Arthur E; O'Brien, John T; Horsburgh, Karen; Ihara, Masafumi; Kalaria, Raj N

    2016-01-01

    White matter hyperintensities as seen on brain T2-weighted magnetic resonance imaging are associated with varying degrees of cognitive dysfunction in stroke, cerebral small vessel disease and dementia. The pathophysiological mechanisms within the white matter accounting for cognitive dysfunction remain unclear. With the hypothesis that gliovascular interactions are impaired in subjects with high burdens of white matter hyperintensities, we performed clinicopathological studies in post-stroke survivors, who had exhibited greater frontal white matter hyperintensities volumes that predicted shorter time to dementia onset. Histopathological methods were used to identify substrates in the white matter that would distinguish post-stroke demented from post-stroke non-demented subjects. We focused on the reactive cell marker glial fibrillary acidic protein (GFAP) to study the incidence and location of clasmatodendrosis, a morphological attribute of irreversibly injured astrocytes. In contrast to normal appearing GFAP+ astrocytes, clasmatodendrocytes were swollen and had vacuolated cell bodies. Other markers such as aldehyde dehydrogenase 1 family, member L1 (ALDH1L1) showed cytoplasmic disintegration of the astrocytes. Total GFAP+ cells in both the frontal and temporal white matter were not greater in post-stroke demented versus post-stroke non-demented subjects. However, the percentage of clasmatodendrocytes was increased by >2-fold in subjects with post-stroke demented compared to post-stroke non-demented subjects (P = 0.026) and by 11-fold in older controls versus young controls (P < 0.023) in the frontal white matter. High ratios of clasmotodendrocytes to total astrocytes in the frontal white matter were consistent with lower Mini-Mental State Examination and the revised Cambridge Cognition Examination scores in post-stroke demented subjects. Double immunofluorescent staining showed aberrant co-localization of aquaporin 4 (AQP4) in retracted GFAP+ astrocytes with disrupted end-feet juxtaposed to microvessels. To explore whether this was associated with the disrupted gliovascular interactions or blood-brain barrier damage, we assessed the co-localization of GFAP and AQP4 immunoreactivities in post-mortem brains from adult baboons with cerebral hypoperfusive injury, induced by occlusion of three major vessels supplying blood to the brain. Analysis of the frontal white matter in perfused brains from the animals surviving 1-28 days after occlusion revealed that the highest intensity of fibrinogen immunoreactivity was at 14 days. At this survival time point, we also noted strikingly similar redistribution of AQP4 and GFAP+ astrocytes transformed into clasmatodendrocytes. Our findings suggest novel associations between irreversible astrocyte injury and disruption of gliovascular interactions at the blood-brain barrier in the frontal white matter and cognitive impairment in elderly post-stroke survivors. We propose that clasmatodendrosis is another pathological substrate, linked to white matter hyperintensities and frontal white matter changes, which may contribute to post-stroke or small vessel disease dementia. © The Author (2015). Published by Oxford University Press on behalf of the Guarantors of Brain.

  2. PSYCHOLOGICAL CONCEPTIONS OF TEACHING.

    ERIC Educational Resources Information Center

    GAGE, N.L.

    A CONCEPTUAL FRAMEWORK WAS PROPOSED FOR AN EDUCATIONAL PSYCHOLOGY COURSE IN THE GENERAL METHODOLOGY OF TEACHING. THIS COURSE WOULD TRANSCEND THE SPECIAL REQUIREMENTS OF ANY GIVEN SUBJECT MATTER OR GRADE LEVEL AND SERVE AS THE BASIS FOR DERIVING THE SPECIAL METHODS OF TEACHING THAT WOULD APPLY TO ANY PARTICULAR GRADE LEVEL OR SUBJECT MATTER.…

  3. Opus in the Classroom: Striking CoRDS with Content-Related Digital Storytelling

    ERIC Educational Resources Information Center

    Roby, Teshia Young

    2010-01-01

    Writing personal narratives provides students with additional techniques for making deeper connections to subject matter. Content-related narrative development offers a departure from the traditional methods of teaching and learning and enables students to construe meaning individually and make deeper connections with subject matter content. By…

  4. Making Acquisition Measurable

    DTIC Science & Technology

    2011-04-30

    Corporation. All rights reserved End Users Administrator/ Maintainer (A/M) Subject Matter Expert ( SME ) Trainer/ Instructor Manager, Evaluator, Supervisor... CMMI ) - Acquisition (AQ) © 2011 The MITRE Corporation. All rights reserved 13 CMMI -Development Incremental iterative development (planning & execution...objectives Constructing games highlighting particular aspects of proposed CCOD® acquisition, and conducting exercises with Subject Matter Experts ( SMEs

  5. The Craft of Teaching. A Guide to Mastering the Professor's Art.

    ERIC Educational Resources Information Center

    Eble, Kenneth E.

    College teaching, teaching skills, and practical problems are considered. The emphasis on subject matter specialization in graduate school and effects on the preparation of college teachers are considered, along with suggestions about what beginning college teachers need to know beyond subject matter training. After briefly considering assumptions…

  6. Principles of Teaching. Module.

    ERIC Educational Resources Information Center

    Rhoades, Joseph W.

    This module on principles of teaching is 1 in a series of 10 modules written for vocational education teacher education programs. It is designed to enable the teacher to do the following: (1) identify subject matter and integrate that subject matter with thought-provoking questions; (2) organize and demonstrate good questioning techniques; and (3)…

  7. 76 FR 7479 - Office of the Ombudsman

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-10

    ... Ombudsman will not consider matters in litigation, arbitration, or mediation. Several commenters requested... Office of Finance by FHFA that is not subject to appeal or in litigation, arbitration, or mediation. The... mediation, unless there has been a breakdown in the process, may not be appealed. Matters not subject to...

  8. The Interdependence of Social Identification and Learning

    ERIC Educational Resources Information Center

    Wortham, Stanton

    2004-01-01

    When students and teachers discuss subject matter, at least two processes generally occur: Students and teachers become socially identified as recognizable types of people, and students learn subject matter. This article contributes to recent work on how social identification and learning systematically interrelate by describing one complex way in…

  9. Expertise in Mathematics Instruction: Subject Matter Knowledge.

    ERIC Educational Resources Information Center

    Leinhardt, Gaea; Smith, Donald

    The relationship between expert teachers' classroom behavior and their subject matter knowledge is an area of research that has not been examined extensively. To begin that study, one topic, fraction knowledge, was explored in depth as it occurred in natural teaching settings. Fractions are one of the more difficult topics in elementary…

  10. 12 CFR 791.6 - Subject matter of a meeting.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ....6 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING THE OPERATIONS OF THE... REGULATIONS; PUBLIC OBSERVATION OF NCUA BOARD MEETINGS Rules of NCUA Board Procedure § 791.6 Subject matter of... all Office Directors and President of the Central Liquidity Facility), and Regional Directors. [61 FR...

  11. 49 CFR 218.4 - Preemptive effect.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... negligence standards apply where there is no Federal action covering the subject matter. Under 49 U.S.C. 20106 (section 20106), issuance of the regulations in this part preempts any State law, regulation, or order covering the same subject matter, except an additional or more stringent law, regulation, or order...

  12. 49 CFR 217.2 - Preemptive effect.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... negligence standards apply where there is no Federal action covering the subject matter. Under 49 U.S.C. 20106 (section 20106), issuance of the regulations in this part preempts any State law, regulation, or order covering the same subject matter, except an additional or more stringent law, regulation, or order...

  13. Particulate matter and black carbon optical properties and emission factors from prescribed fires in the southeastern United States

    EPA Pesticide Factsheets

    This dataset provides all data used to generate the figures and tables in the article entitled Particulate matter and black carbon optical properties and emission factors from prescribed fires in the southeastern United States published in the Journal of Geophysical Research: AtmospheresThis dataset is associated with the following publication:Holder , A., G. Hagler , J. Aurell, M. Hays , and B. Gullett. Particulate matter and black carbon optical properties and emission factors from prescribed fires in the southeastern United States. JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES. American Geophysical Union, Washington, DC, USA, 121(7): 3465-3483, (2016).

  14. Being in a Romantic Relationship Is Associated with Reduced Gray Matter Density in Striatum and Increased Subjective Happiness

    PubMed Central

    Kawamichi, Hiroaki; Sugawara, Sho K.; Hamano, Yuki H.; Makita, Kai; Matsunaga, Masahiro; Tanabe, Hiroki C.; Ogino, Yuichi; Saito, Shigeru; Sadato, Norihiro

    2016-01-01

    Romantic relationship, a widespread feature of human society, is one of the most influential factors in daily life. Although stimuli related to romantic love or being in a romantic relationship commonly result in enhancement of activation or functional connectivity of the reward system, including the striatum, the structure underlying romantic relationship-related regions remain unclear. Because individual experiences can alter gray matter within the adult human brain, we hypothesized that romantic relationship is associated with structural differences in the striatum related to the positive subjective experience of being in a romantic relationship. Because intimate romantic relationships contribute to perceived subjective happiness, this subjective enhancement of happiness might be accompanied by the experience of positive events related to being in a romantic relationship. To test this hypothesis and elucidate the structure involved, we compared subjective happiness, an indirect measure of the existence of positive experiences caused by being in a romantic relationship, of participants with or without romantic partners (N = 68). Furthermore, we also conducted a voxel-based morphometry study of the effects of being in a romantic relationship (N = 113). Being in a romantic relationship was associated with greater subjective happiness and reduced gray matter density within the right dorsal striatum. These results suggest that being in a romantic relationship enhances perceived subjective happiness via positive experiences. Furthermore, the observed reduction in gray matter density in the right dorsal striatum may reflect an increase in saliency of social reward within a romantic relationship. Thus, being in a romantic relationship is associated with positive experiences and a reduction of gray matter density in the right dorsal striatum, representing a modulation of social reward. PMID:27895606

  15. Major Superficial White Matter Abnormalities in Huntington's Disease

    PubMed Central

    Phillips, Owen R.; Joshi, Shantanu H.; Squitieri, Ferdinando; Sanchez-Castaneda, Cristina; Narr, Katherine; Shattuck, David W.; Caltagirone, Carlo; Sabatini, Umberto; Di Paola, Margherita

    2016-01-01

    Background: The late myelinating superficial white matter at the juncture of the cortical gray and white matter comprising the intracortical myelin and short-range association fibers has not received attention in Huntington's disease. It is an area of the brain that is late myelinating and is sensitive to both normal aging and neurodegenerative disease effects. Therefore, it may be sensitive to Huntington's disease processes. Methods: Structural MRI data from 25 Pre-symptomatic subjects, 24 Huntington's disease patients and 49 healthy controls was run through a cortical pattern-matching program. The surface corresponding to the white matter directly below the cortical gray matter was then extracted. Individual subject's Diffusion Tensor Imaging (DTI) data was aligned to their structural MRI data. Diffusivity values along the white matter surface were then sampled at each vertex point. DTI measures with high spatial resolution across the superficial white matter surface were then analyzed with the General Linear Model to test for the effects of disease. Results: There was an overall increase in the axial and radial diffusivity across much of the superficial white matter (p < 0.001) in Pre-symptomatic subjects compared to controls. In Huntington's disease patients increased diffusivity covered essentially the whole brain (p < 0.001). Changes are correlated with genotype (CAG repeat number) and disease burden (p < 0.001). Conclusions: This study showed broad abnormalities in superficial white matter even before symptoms are present in Huntington's disease. Since, the superficial white matter has a unique microstructure and function these abnormalities suggest it plays an important role in the disease. PMID:27242403

  16. Les phénols de la lignine et le 13C, traceurs de l'origine des matières organiques du solLabelling the origin of soil organic matter by lignin phenols and 13C natural abundance

    NASA Astrophysics Data System (ADS)

    Jolivet, Claudy; Guillet, Bernard; Karroum, Michel; Andreux, Francis; Bernoux, Martial; Arrouays, Dominique

    2001-11-01

    In spodosols of Gascony (France), conversion of maritime pine stands into maize cropping leads to an incorporation of maize organic matter, which changed the isotopic ( δ13C) and phenolic signature in A and L horizons of soil. Hydrolysis of phenol lignin in forests and cultivated soils showed the predominance of vanillic units under forest and the early but moderate incorporation of cinnamic acids. Incorporation of syringic units appeared higher, related to a large maize production of stable syringic phenols. Syringic units represented a long-term marker of maize inputs in soils, whereas vanillic units revealed the degradation of forest organic matter.

  17. Unlicensed care homes in the United States: a clandestine sector of long-term care.

    PubMed

    Lepore, Michael; Greene, Angela M; Porter, Kristie; Lux, Linda; Vreeland, Emily; Hawes, Catherine

    2018-06-11

    Residential care facilities operating without a state license are known to house vulnerable adults. Such unlicensed care homes (UCHs) commonly operate illegally, making them difficult to investigate. We conducted an exploratory, multimethod qualitative study of UCHs, including 18 subject matter expert interviews and site visits to three states, including a total of 30 stakeholder interviews, to understand UCH operations, services provided, and residents served. Findings indicate that various vulnerable groups reside in UCHs; some UCHs offer unsafe living environments; and some residents are reportedly abused, neglected, and financially exploited. Regulations, policies and practices that might influence UCH prevalence are discussed.

  18. On describing human white matter anatomy: the white matter query language.

    PubMed

    Wassermann, Demian; Makris, Nikos; Rathi, Yogesh; Shenton, Martha; Kikinis, Ron; Kubicki, Marek; Westin, Carl-Fredrik

    2013-01-01

    The main contribution of this work is the careful syntactical definition of major white matter tracts in the human brain based on a neuroanatomist's expert knowledge. We present a technique to formally describe white matter tracts and to automatically extract them from diffusion MRI data. The framework is based on a novel query language with a near-to-English textual syntax. This query language allows us to construct a dictionary of anatomical definitions describing white matter tracts. The definitions include adjacent gray and white matter regions, and rules for spatial relations. This enables automated coherent labeling of white matter anatomy across subjects. We use our method to encode anatomical knowledge in human white matter describing 10 association and 8 projection tracts per hemisphere and 7 commissural tracts. The technique is shown to be comparable in accuracy to manual labeling. We present results applying this framework to create a white matter atlas from 77 healthy subjects, and we use this atlas in a proof-of-concept study to detect tract changes specific to schizophrenia.

  19. 37 CFR 11.9 - Limited recognition in patent matters.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Limited recognition in patent matters. 11.9 Section 11.9 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE REPRESENTATION OF OTHERS BEFORE THE UNITED STATES PATENT AND TRADEMARK OFFICE...

  20. 37 CFR 11.9 - Limited recognition in patent matters.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Limited recognition in patent matters. 11.9 Section 11.9 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE REPRESENTATION OF OTHERS BEFORE THE UNITED STATES PATENT AND TRADEMARK OFFICE...

  1. 37 CFR 11.9 - Limited recognition in patent matters.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Limited recognition in patent matters. 11.9 Section 11.9 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE REPRESENTATION OF OTHERS BEFORE THE UNITED STATES PATENT AND TRADEMARK OFFICE...

  2. 37 CFR 11.9 - Limited recognition in patent matters.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2012-07-01 2012-07-01 false Limited recognition in patent matters. 11.9 Section 11.9 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE REPRESENTATION OF OTHERS BEFORE THE UNITED STATES PATENT AND TRADEMARK OFFICE...

  3. 37 CFR 11.9 - Limited recognition in patent matters.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Limited recognition in patent matters. 11.9 Section 11.9 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE REPRESENTATION OF OTHERS BEFORE THE UNITED STATES PATENT AND TRADEMARK OFFICE...

  4. The median density of the Universe

    NASA Astrophysics Data System (ADS)

    Stücker, Jens; Busch, Philipp; White, Simon D. M.

    2018-07-01

    Despite the fact that the mean matter density of the Universe has been measured to an accuracy of a few per cent within the standard Λcold dark matter (ΛCDM) paradigm, its median density is not known even to the order of magnitude. Typical points lie in low-density regions and are not part of a collapsed structure of any scale. Locally, the dark matter distribution is then simply a stretched version of that in the early Universe. In this single-stream regime, the distribution of unsmoothed density is sensitive to the initial power spectrum on all scales, in particular on very small scales, and hence to the nature of the dark matter. It cannot be estimated reliably using conventional cosmological simulations because of the enormous dynamic range involved, but a suitable excursion set procedure can be used instead. For the Planck cosmological parameters, a 100 GeV WIMP, corresponding to a free-streaming mass ˜10-6M⊙, results in a median density of ˜4 × 10-3 in units of the mean density, whereas a 10 μeV axion with free-streaming mass ˜10-12M⊙ gives ˜3 × 10-3, and warm dark matter (WDM) with a (thermal relic) mass of 1 keV gives ˜8 × 10-2. In CDM (but not in WDM) universes, single-stream regions are predicted to be topologically isolated by the excursion set formalism. A test by direct N-body simulations seems to confirm this prediction, although it is still subject to finite size and resolution effects. Unfortunately, it is unlikely that any of these properties is observable and so suitable for constraining the properties of dark matter.

  5. 77 FR 28642 - Sunshine Act Meeting Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-15

    ... information and to ascertain what, if any, matters have been added, deleted or postponed, please contact the... scheduled matters at the Closed Meeting. Certain staff members who have an interest in the matters also may... Meeting in closed session, and determined that no earlier notice thereof was possible. The subject matter...

  6. 37 CFR 2.176 - Consideration of above matters.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... matters. 2.176 Section 2.176 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE... Consideration of above matters. The matters in §§ 2.171 to 2.175 will be considered in the first instance by the... examiner within six months of the date of issuance, the matter will be considered abandoned. [73 FR 67774...

  7. 37 CFR 2.176 - Consideration of above matters.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... matters. 2.176 Section 2.176 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE... Consideration of above matters. The matters in §§ 2.171 to 2.175 will be considered in the first instance by the... examiner within six months of the date of issuance, the matter will be considered abandoned. [73 FR 67774...

  8. 37 CFR 2.176 - Consideration of above matters.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... matters. 2.176 Section 2.176 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE... Consideration of above matters. The matters in §§ 2.171 to 2.175 will be considered in the first instance by the... examiner within six months of the date of issuance, the matter will be considered abandoned. [73 FR 67774...

  9. A Multidimensional Investigation of Deep-Level and Surface-Level Processing

    ERIC Educational Resources Information Center

    Dinsmore, Daniel L.; Alexander, Patricia A.

    2016-01-01

    This study examines the moderating effects of a situational factor (i.e., text type) and an individual factor (i.e., subject-matter knowledge) on the relation between depth of processing and performance. One-hundred and fifty-one undergraduates completed measures of subject-matter knowledge, read either an expository or persuasive text about the…

  10. Reflective Pedagogy: The Integration of Methodology and Subject-Matter Content in a Graduate-Level Course

    ERIC Educational Resources Information Center

    Jakeman, Rick C.; Henderson, Markesha M.; Howard, Lionel C.

    2017-01-01

    This article presents a critical reflection on how we, instructors of a graduate-level course in higher education administration, sought to integrate theoretical and subject-matter content and research methodology. Our reflection, guided by autoethnography and teacher reflection, challenged both our assumptions about curriculum design and our…

  11. Educational Content of Basal Reading Texts: Implications for Comprehension Instruction.

    ERIC Educational Resources Information Center

    Schmidt, William H.; And Others

    To explore the issue of educational content in basal readers, a study analyzed 34 basal reading textbooks, representing eight of the most commonly used series in American elementary education. Educational content was defined and categorized along three dimensions: subject matter, function, and ethos. The subject matter component covered theories,…

  12. Subject Matter Counts: The Pre-Service Teaching and Learning of Historical Thinking

    ERIC Educational Resources Information Center

    Keirn, Tim; Luhr, Eileen

    2012-01-01

    The American Historical Association (AHA) and the National Council for History Education (NCHE) have recently advocated for raising the visibility of historians--and the significance of history coursework and subject matter preparation--in pre-service history teacher education. In 2006, NCHE adopted a position statement on history teacher…

  13. 50 CFR 91.14 - Restrictions on subject matter for entry.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Procedures for Entering the Contest § 91.14 Restrictions on subject matter for entry. A live portrayal of any... creation. The entry design may not be copied or duplicated from previously published art, including photographs, or from images in any format published on the Internet. Photographs, computer-generated art, or...

  14. 50 CFR 91.14 - Restrictions on subject matter for entry.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Procedures for Entering the Contest § 91.14 Restrictions on subject matter for entry. A live portrayal of any... creation. The entry design may not be copied or duplicated from previously published art, including photographs, or from images in any format published on the Internet. Photographs, computer-generated art, or...

  15. Shared Knowledge among Graphic Designers, Instructional Designers and Subject Matter Experts in Designing Multimedia-Based Instructional Media

    ERIC Educational Resources Information Center

    Razak, Rafiza Abdul

    2013-01-01

    The research identified and explored the shared knowledge among the instructional multimedia design and development experts comprising of subject matter expert, graphic designer and instructional designer. The knowledge shared by the team was categorized into three groups of multimedia design principles encompasses of basic principles, authoring…

  16. 78 FR 70583 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-26

    ... substantial interest in the subject matter of the investigations may request a public hearing, provided such... regarding the subject matter of the investigations to the Director, Office of Trade Adjustment [[Page 70584...-Sylvania (Company)...... Wellsboro, PA 11/04/13 10/21/13 83193 REO Group Properties, LLC Pasadena, CA 11/04...

  17. Conceptualizations of Representation Forms and Knowledge Organization of High School Teachers in Finland: "Magnetostatics"

    ERIC Educational Resources Information Center

    Majidi, Sharareh; Emden, Markus

    2013-01-01

    One of the main components of teachers' pedagogical content knowledge refers to their use of representation forms. In a similar vein, organizing concepts logically and meaningfully is an essential element of teachers' subject matter knowledge. Since subject matter and pedagogical content knowledge of teachers are tightly connected as categories…

  18. Overarching Goals, Values, and Assumptions of Integrated Curriculum Design

    ERIC Educational Resources Information Center

    Anderson, Denise M.

    2013-01-01

    The integration of one's curriculum is an approach to education that ignores subject-matter lines of delineation, thus allowing faculty to bring together the separate pieces of a curriculum into a coherent whole that facilitates meaningful associations across subject matter. Before taking on the challenge of curriculum integration, faculty…

  19. Interdisciplinary Study: Research as Part of Artmaking

    ERIC Educational Resources Information Center

    Eubanks, Paula

    2012-01-01

    As education budgets shrink, art teachers need to find ways to position the study of art closer to mainstream academics by exploring concepts that cut across disciplinary boundaries. Art teachers can challenge students to do serious and thorough research about subject matter partnering with teachers in other areas to select subject matter that is…

  20. 10 CFR 54.30 - Matters not subject to a renewal review.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... FOR NUCLEAR POWER PLANTS General Provisions § 54.30 Matters not subject to a renewal review. (a) If... licensee shall take measures under its current license, as appropriate, to ensure that the intended... (a) of this section to take measures under its current license is not within the scope of the license...

  1. Subject-Matter Determines Method.

    ERIC Educational Resources Information Center

    Guth, Hans P.

    Only the approach that integrates a study of both the "what" and the "how" of a discipline will be relevant to the practicing English teacher. Missing between the two extremes of specialized subject matter research and conventional educational research is research into the structure of a particular discipline, exploring it as a body of knowledge,…

  2. Closing down the Conversation: Discouraging Student Talk on Unfamilar Science Content

    ERIC Educational Resources Information Center

    Carlsen, William

    2015-01-01

    This paper describes strategies used by novice biology teachers to exert sociolinguistic control over conversations when teaching unfamiliar subject-matter content. These discourse control strategies were identified in a year-long study of teacher subject-matter knowledge and its effects on teaching, and are illustrated in three lessons taught by…

  3. Cultivating Early Trajectories of Participation: A Blended Learning Environment for Business German

    ERIC Educational Resources Information Center

    Neville, David O.

    2016-01-01

    The essay forwards suggestions for developing a blended learning environment to insert genre-based language for specific purposes (LSP) subject matter into the undergraduate second language development curriculum. Specifically, the essay will highlight: (1) the development of an overarching narrative for structuring the LSP subject matter; (2) the…

  4. Harnessing Open Technologies to Promote Open Educational Knowledge Sharing

    ERIC Educational Resources Information Center

    Iiyoshi, Toru; Richardson, Cheryl; McGrath, Owen

    2006-01-01

    An oft-noted shortcoming of the research on teaching has been the meager description of teachers' knowledge and experience: their intellectual engagement with the subject matter they teach, their understanding of how to manage ideas in their teaching, or even their conceptions of how students develop knowledge of the subject matter taught. To…

  5. Preservice and Experienced Biology Teachers' Global and Specific Subject Matter Structures: Implications for Conceptions of Pedagogical Content Knowledge

    ERIC Educational Resources Information Center

    Abd-El-Khalick, Fouad

    2006-01-01

    This study aimed to describe preservice and experienced secondary biology teachers' global and specific subject matter structures (SMSs) and elucidate the relationship between these structures and teaching experience. Teachers' global and specific SMSs respectively designate their conceptions and/or organization of their disciplines and of…

  6. With an Eye on the Mathematical Horizon: Dilemmas of Teaching Elementary School Mathematics. Craft Paper 90-3.

    ERIC Educational Resources Information Center

    Ball, Deborah Loewenberg

    Much educational discourse centers on the importance of teachers' subject matter knowledge. Complementing concerns for subject matter knowledge is interest in developing and studying alternative pedagogies that emphasize active learning and meaningful engagement. Teaching and learning would be improved, so the argument goes, if classrooms were…

  7. Developing Statistical Knowledge for Teaching during Design-Based Research

    ERIC Educational Resources Information Center

    Groth, Randall E.

    2017-01-01

    Statistical knowledge for teaching is not precisely equivalent to statistics subject matter knowledge. Teachers must know how to make statistics understandable to others as well as understand the subject matter themselves. This dual demand on teachers calls for the development of viable teacher education models. This paper offers one such model,…

  8. The Implementation of APIQ Creative Mathematics Game Method in the Subject Matter of Greatest Common Factor and Least Common Multiple in Elementary School

    NASA Astrophysics Data System (ADS)

    Rahman, Abdul; Saleh Ahmar, Ansari; Arifin, A. Nurani M.; Upu, Hamzah; Mulbar, Usman; Alimuddin; Arsyad, Nurdin; Ruslan; Rusli; Djadir; Sutamrin; Hamda; Minggi, Ilham; Awi; Zaki, Ahmad; Ahmad, Asdar; Ihsan, Hisyam

    2018-01-01

    One of causal factors for uninterested feeling of the students in learning mathematics is a monotonous learning method, like in traditional learning method. One of the ways for motivating students to learn mathematics is by implementing APIQ (Aritmetika Plus Intelegensi Quantum) creative mathematics game method. The purposes of this research are (1) to describe students’ responses toward the implementation of APIQ creative mathematics game method on the subject matter of Greatest Common Factor (GCF) and Least Common Multiple (LCM) and (2) to find out whether by implementing this method, the student’s learning completeness will improve or not. Based on the results of this research, it is shown that the responses of the students toward the implementation of APIQ creative mathematics game method in the subject matters of GCF and LCM were good. It is seen in the percentage of the responses were between 76-100%. (2) The implementation of APIQ creative mathematics game method on the subject matters of GCF and LCM improved the students’ learning.

  9. Methamphetamine users show greater than normal age-related cortical gray matter loss.

    PubMed

    Nakama, Helenna; Chang, Linda; Fein, George; Shimotsu, Ryan; Jiang, Caroline S; Ernst, Thomas

    2011-08-01

    Methamphetamine (Meth) abuse continues to be a major illicit drug of abuse. Neuroimaging findings suggest that Meth is neurotoxic and may alter various brain structures, but the effect of Meth on the aging brain has not been studied. The aim was to determine regional volumes of cortical gray matter in the brains of adult Meth users versus healthy control subjects, and their interaction with age and Meth-usage variables. Cross-sectional study Magnetic resonance imaging (MRI) Research Center located in a university-affiliated hospital. Thirty-four Meth-dependent subjects (21 men and 13 women; ages 33.1 ± 8.9 years), diagnosed according to DSM-IV criteria, and 31 healthy non-Meth user comparison subjects (23 men and 8 women ages 35.7 ± 8.4 years). Regional gray matter volumes were segmented automatically in all subjects and evaluated in relation to age, using high-resolution MRIs at 3.0 Tesla. After adjustment for the effects of cranium size, the Meth users showed enhanced cortical gray matter volume loss with age in the frontal (analysis of covariance interaction P = 0.02), occipital (interaction P = 0.01), temporal (interaction P < 0.001) and the insular lobes (interaction P = 0.01) compared to controls, independently of Meth-usage patterns. Additionally, Meth users showed smaller gray matter volumes than control subjects in several subregions (dorsolateral prefrontal: P = 0.02; orbitofrontal: P = 0.03; prefrontal: P = 0.047; superior temporal: P = 0.04). Methamphetamine users appear to show increased cortical gray matter loss with age which raises the possibility of accelerated decline in mental functioning. © 2011 The Authors, Addiction © 2011 Society for the Study of Addiction.

  10. Pigs in cyberspace

    NASA Technical Reports Server (NTRS)

    Moravec, Hans

    1993-01-01

    Exploration and colonization of the universe awaits, but Earth-adapted biological humans are ill-equipped to respond to the challenge. Machines have gone farther and seen more, limited though they presently are by insect-like behavior inflexibility. As they become smarter over the coming decades, space will be theirs. Organizations of robots of ever increasing intelligence and sensory and motor ability will expand and transform what they occupy, working with matter, space and time. As they grow, a smaller and smaller fraction of their territory will be undeveloped frontier. Competitive success will depend more and more on using already available matter and space in ever more refined and useful forms. The process, analogous to the miniaturization that makes today's computers a trillion times more powerful than the mechanical calculators of the past, will gradually transform all activity from grossly physical homesteading of raw nature, to minimum-energy quantum transactions of computation. The final frontier will be urbanized, ultimately into an arena where every bit of activity is a meaningful computation: the inhabited portion of the universe will be transformed into a cyberspace. Because it will use resources more efficiently, a mature cyberspace of the distant future will be effectively much bigger than the present physical universe. While only an infinitesimal fraction of existing matter and space is doing interesting work, in a well developed cyberspace every bit will be part of a relevant computation or storing a useful datum. Over time, more compact and faster ways of using space and matter will be invented, and used to restructure the cyberspace, effectively increasing the amount of computational spacetime per unit of physical spacetime. Computational speed-ups will affect the subjective experience of entities in the cyberspace in a paradoxical way. At first glimpse, there is no subjective effect, because everything, inside and outside the individual, speeds up equally. But, more subtly, speed-up produces an expansion of the cyber universe, because, as thought accelerates, more subjective time passes during the fixed (probably lightspeed) physical transit time of a message between a given pair of locations - so those fixed locations seem to grow farther apart. Also, as information storage is made continually more efficient through both denser utilization of matter and more efficient encodings, there will be increasingly more cyber-stuff between any two points. The effect may somewhat resemble the continuous-creation process in the old steady-state theory of the physical universe of Hoyle, Bondi and Gold, where hydrogen atoms appear just fast enough throughout the expanding cosmos to maintain a constant density.

  11. Gray Matter Network Disruptions and Regional Amyloid Beta in Cognitively Normal Adults.

    PubMed

    Ten Kate, Mara; Visser, Pieter Jelle; Bakardjian, Hovagim; Barkhof, Frederik; Sikkes, Sietske A M; van der Flier, Wiesje M; Scheltens, Philip; Hampel, Harald; Habert, Marie-Odile; Dubois, Bruno; Tijms, Betty M

    2018-01-01

    The accumulation of amyloid plaques is one of the earliest pathological changes in Alzheimer's disease (AD) and may occur 20 years before the onset of symptoms. Examining associations between amyloid pathology and other early brain changes is critical for understanding the pathophysiological underpinnings of AD. Alterations in gray matter networks might already start at early preclinical stages of AD. In this study, we examined the regional relationship between amyloid aggregation measured with positron emission tomography (PET) and gray matter network measures in elderly subjects with subjective memory complaints. Single-subject gray matter networks were extracted from T1-weigthed structural MRI in cognitively normal subjects ( n = 318, mean age 76.1 ± 3.5, 64% female, 28% amyloid positive). Degree, clustering, path length and small world properties were computed. Global and regional amyloid load was determined using [ 18 F]-Florbetapir PET. Associations between standardized uptake value ratio (SUVr) values and network measures were examined using linear regression models. We found that higher global SUVr was associated with lower clustering ( β = -0.12, p < 0.05), and small world values ( β = -0.16, p < 0.01). Associations were most prominent in orbito- and dorsolateral frontal and parieto-occipital regions. Local SUVr values showed less anatomical variability and did not convey additional information beyond global amyloid burden. In conclusion, we found that in cognitively normal elderly subjects, increased global amyloid pathology is associated with alterations in gray matter networks that are indicative of incipient network breakdown towards AD dementia.

  12. Alterations of neocortico-limbic association fibers and correlation with diet in prediabetes diagnosed by impaired fasting glucose.

    PubMed

    Hou, Yi-Cheng; Yang, Shwu-Huey; Wu, Yu-Te; Lai, Chien-Han

    2016-06-01

    To assess the existence of alterations in the micro-integrity of the fasciculus in prediabetic subjects. The issue of micro-integrity in white matter tracts has not been adequately addressed in prediabetes. Sixty-four prediabetic subjects and 54 controls were enrolled. All participants completed 24-hour diet records and 3-day diet records and received diffusion tensor imaging at 3T. The data for white matter micro-integrity were analyzed and compared between prediabetic subjects and controls with age and gender as covariates. In addition, voxel-wise regression between white matter micro-integrity, diet, and preprandial glucose levels were used to explore the relationship between white matter micro-integrity and diet or serum glucose levels. We found that prediabetic subjects had significant reductions in the micro-integrity of bilateral anterior thalamic radiation, left inferior longitudinal fasciculus, and left superior longitudinal fasciculus (corrected P < 0.05). In addition, total carbohydrate intake amount and preprandial serum glucose levels were negatively correlated with the micro-integrity in the left inferior longitudinal fasciculus and left anterior thalamic radiation (r: -0.47, corrected P < 0.05). Restrictive alterations in the white matter micro-integrity of the anterior thalamic radiation and inferior and superior longitudinal fasciculi might represent the initial "hot spots" for white matter tract alterations, which might play a role in the development of prediabetes. J. Magn. Reson. Imaging 2016;43:1500-1506. © 2016 Wiley Periodicals, Inc.

  13. Why Is the Teen Birth Rate in the United States so High and Why Does It Matter? NBER Working Paper No. 17965

    ERIC Educational Resources Information Center

    Kearney, Melissa Schettini; Levine, Phillip B.

    2012-01-01

    This paper examines two aspects of teen childbearing in the United States. First, it reviews and synthesizes the evidence on the reasons why teen birth rates are so uniquely high in the United States and especially in some states. Second, it considers why and how it matters. We argue that economists' typical explanations are unable to account for…

  14. Correlating Cognitive Decline with White Matter Lesion and Brain Atrophy MRI Measurements in Alzheimer’s Disease

    PubMed Central

    Bilello, Michel; Doshi, Jimit; Nabavizadeh, S. Ali; Toledo, Jon B.; Erus, Guray; Xie, Sharon X.; Trojanowski, John Q.; Han, Xiaoyan; Davatzikos, Christos

    2015-01-01

    Background Vascular risk factors are increasingly recognized as risks factors for Alzheimer’s disease (AD) and early conversion from mild cognitive impairment (MCI) to dementia. While neuroimaging research in AD has focused on brain atrophy, metabolic function or amyloid deposition, little attention has been paid to the effect of cerebrovascular disease to cognitive decline. Objective To investigate the correlation of brain atrophy and white matter lesions with cognitive decline in AD, MCI, and control subjects. Methods Patients with AD and MCI, and healthy subjects were included in this study. Subjects had a baseline MRI scan, and baseline and follow-up neuropsychological battery (CERAD). Regional volumes were measured, and white matter lesion segmentation was performed. Correlations between rate of CERAD score decline and white matter lesion load and brain structure volume were evaluated. In addition, voxel-based correlations between baseline CERAD scores and atrophy and white matter lesion measures were computed. Results CERAD rate of decline was most significantly associated with lesion loads located in the fornices. Several temporal lobe ROI volumes were significantly associated with CERAD decline. Voxel-based analysis demonstrated strong correlation between baseline CERAD scores and atrophy measures in the anterior temporal lobes. Correlation of baseline CERAD scores with white matter lesion volumes achieved significance in multilobar subcortical white matter. Conclusion Both baseline and declines in CERAD scores correlate with white matter lesion load and gray matter atrophy. Results of this study highlight the dominant effect of volume loss, and underscore the importance of small vessel disease as a contributor to cognitive decline in the elderly. PMID:26402108

  15. Correlating Cognitive Decline with White Matter Lesion and Brain Atrophy Magnetic Resonance Imaging Measurements in Alzheimer's Disease.

    PubMed

    Bilello, Michel; Doshi, Jimit; Nabavizadeh, S Ali; Toledo, Jon B; Erus, Guray; Xie, Sharon X; Trojanowski, John Q; Han, Xiaoyan; Davatzikos, Christos

    2015-01-01

    Vascular risk factors are increasingly recognized as risks factors for Alzheimer's disease (AD) and early conversion from mild cognitive impairment (MCI) to dementia. While neuroimaging research in AD has focused on brain atrophy, metabolic function, or amyloid deposition, little attention has been paid to the effect of cerebrovascular disease to cognitive decline. To investigate the correlation of brain atrophy and white matter lesions with cognitive decline in AD, MCI, and control subjects. Patients with AD and MCI, and healthy subjects were included in this study. Subjects had a baseline MRI scan, and baseline and follow-up neuropsychological battery (CERAD). Regional volumes were measured, and white matter lesion segmentation was performed. Correlations between rate of CERAD score decline and white matter lesion load and brain structure volume were evaluated. In addition, voxel-based correlations between baseline CERAD scores and atrophy and white matter lesion measures were computed. CERAD rate of decline was most significantly associated with lesion loads located in the fornices. Several temporal lobe ROI volumes were significantly associated with CERAD decline. Voxel-based analysis demonstrated strong correlation between baseline CERAD scores and atrophy measures in the anterior temporal lobes. Correlation of baseline CERAD scores with white matter lesion volumes achieved significance in multilobar subcortical white matter. Both baseline and declines in CERAD scores correlate with white matter lesion load and gray matter atrophy. Results of this study highlight the dominant effect of volume loss, and underscore the importance of small vessel disease as a contributor to cognitive decline in the elderly.

  16. What Is the Methodologic Quality of Human Therapy Studies in ISI Surgical Publications?

    PubMed Central

    Manterola, Carlos; Pineda, Viviana; Vial, Manuel; Losada, Héctor

    2006-01-01

    Objective: To determine the methodologic quality of therapy articles about humans published in ISI surgical journals, and to explore the association between methodologic quality, origin, and subject matter. Summary Background Data: It is supposed that ISI journals contain the best methodologic articles. Methods: This is a bibliometric study. All journals listed in the 2002 ISI under the subject heading of “Surgery” were included. A simple randomized sampling was conducted for selected journals (Annals of Surgery, The American Surgeon, Archives of Surgery, British Journal of Surgery, European Journal of Surgery, Journal of the American College of Surgeons, Surgery, and World Journal of Surgery). Published articles related to therapy on humans of the selected journals were reviewed and analyzed. All kinds of clinical designs were considered, excluding editorials, review articles, letters to the editor, and experimental studies. The variables considered were: place of origin, design, and the methodologic quality of articles, which was determined by applying a valid and reliable scale. The review was performed interchangeably and independently by 2 research teams. Descriptive and analytical statistics were used. Statistical significance was defined as P values less than 1%. Results: A total of 653 articles were studied. Studies came predominantly from the United States and Europe (43.6% and 36.8%, respectively). The subject areas most frequently found were digestive and hepatobiliopancreatic surgery (29.1% and 24.5%, respectively). Average and median methodologic quality scores of the entire series were 11.6 ± 4.9 points and 11 points, respectively. The association between methodologic quality and journals was determined. Also, the association between methodologic quality and origin was observed, but no association with subject area was verified. Conclusions: The methodologic quality of therapy articles published in the journals analyzed is low; however, statistical significance was determined between them. Association was observed between methodologic quality and origin, but not with subject matter. PMID:17060778

  17. Reading materials for post-literacy: The development and testing of a model of social writing

    NASA Astrophysics Data System (ADS)

    Bhola, Harbans S.

    1989-12-01

    A model of social writing, for use in writing socially relevant, easy-to-read, follow-up books for neo-literate adults, is presented. The model was fully developed and tested in the context of a series of writers' workshops during 1981-87; and incorporates all of the three aspects of writing: the expressive, the cognitive, and the social. Specifically, the following elements are included: selection of subject and topic within a dialectic of national development needs and community learning needs; negotiable definitions of general and specific objectives; acquiring knowledge of subject matter, and establishing necessary collaboration with subject-matter specialists; content planning to choose content and language of discourse, participatively with the future community of readers; choice of treatment of content as didactic or dramatic; outlining of manuscript as argument, dialogue or story; writing easy-to-read yet interesting materials; trying out the manuscript and making revisions; working with the illustrator and the editor; and preparing the manuscript for printing. Both the development and the testing of the model involved reflection-in-action and not stand-alone research exercises. The successful use of the model in workshops to train writers of post-literacy materials provided one source of support for the model. A comparison of this model of social writing with other models of writing available in literature has provided further support for the conceptual and procedural structure of the model. Transfers of the model to other cultural settings as well as to the writing of other types of educational materials, such as distance education texts and units, have also proved effective.

  18. 75 FR 24743 - In the Matter of Certain Game Controllers; Notice of Investigation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-05

    ... INTERNATIONAL TRADE COMMISSION [Inv. No. 337-TA-715] In the Matter of Certain Game Controllers... States, the sale for importation, and the sale within the United States after importation of certain game... States, the sale for importation, or the sale within the United States after importation of certain game...

  19. 75 FR 63857 - In the Matter of: Certain Digital Televisions and Components Thereof; Notice of Investigation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-18

    ... INTERNATIONAL TRADE COMMISSION [Inv. No. 337-TA-742] In the Matter of: Certain Digital Televisions... importation, and the sale within the United States after importation of certain digital televisions and... sale within the United States after importation of certain digital televisions and components thereof...

  20. 75 FR 51285 - In the Matter of Certain Flat Panel Digital Televisions and Components Thereof; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-19

    ... INTERNATIONAL TRADE COMMISSION [Inv. No. 337-TA-733] In the Matter of Certain Flat Panel Digital... importation, and the sale within the United States after importation of certain flat panel digital televisions... sale within the United States after importation of certain flat panel digital televisions and...

  1. 76 FR 13661 - In the Matter of Certain Connecting Devices (“Quick Clamps”) for Use With Modular Compressed Air...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-14

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-587] In the Matter of Certain Connecting Devices (``Quick Clamps'') for Use With Modular Compressed Air Conditioning Units, Including Filters, Regulators, and Lubricators (``FRL's'') That Are Part of Larger Pneumatic Systems and the FRL Units They...

  2. 75 FR 63198 - In the Matter of Certain Connecting Devices (“Quick Clamps”) for Use With Modular Compressed Air...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-14

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-587] In the Matter of Certain Connecting Devices (``Quick Clamps'') for Use With Modular Compressed Air Conditioning Units, Including Filters, Regulators, and Lubricators (``Frl's'') That Are Part of Larger Pneumatic Systems and the FRL Units They...

  3. Particulate matter and black carbon optical properties and emission factors from prescribed fires in the southeastern United States

    EPA Science Inventory

    The aerosol emissions from prescribed fires in the Southeastern United States were measured and compared to emissions from laboratory burns with fuels collected from the site. Fine particulate matter (PM2.5), black carbon, and aerosol light scattering and absorption were characte...

  4. 37 CFR 11.5 - Register of attorneys and agents in patent matters; practice before the Office.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... agents in patent matters; practice before the Office. 11.5 Section 11.5 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE REPRESENTATION OF OTHERS BEFORE THE UNITED STATES PATENT AND TRADEMARK OFFICE Recognition To Practice Before the USPTO Patents...

  5. 37 CFR 11.5 - Register of attorneys and agents in patent matters; practice before the Office.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... agents in patent matters; practice before the Office. 11.5 Section 11.5 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE REPRESENTATION OF OTHERS BEFORE THE UNITED STATES PATENT AND TRADEMARK OFFICE Recognition To Practice Before the USPTO Patents...

  6. 37 CFR 11.5 - Register of attorneys and agents in patent matters; practice before the Office.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... agents in patent matters; practice before the Office. 11.5 Section 11.5 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE REPRESENTATION OF OTHERS BEFORE THE UNITED STATES PATENT AND TRADEMARK OFFICE Recognition To Practice Before the USPTO Patents...

  7. Unit: Model for Matter, Inspection Pack, National Trial Print.

    ERIC Educational Resources Information Center

    Australian Science Education Project, Toorak, Victoria.

    Mental and physical models are treated in the Australian Science Education Project trial unit prepared for students in a transitional stage between concrete and abstract reasoning. Students are introduced to the particle model of matter through a series of core activities, including a combination game using nuts and bolts, culminating in a…

  8. 42 CFR 405.1887 - Notice of reopening; effect of reopening.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... decision that is the subject of the reopening, informing the parties as to what matter(s), if any, is... extend appeal rights. Any matter that is reconsidered during the course of a reopening, but is not...

  9. 42 CFR 405.1887 - Notice of reopening; effect of reopening.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... decision that is the subject of the reopening, informing the parties as to what matter(s), if any, is... extend appeal rights. Any matter that is reconsidered during the course of a reopening, but is not...

  10. Bootstrapping white matter segmentation, Eve++

    NASA Astrophysics Data System (ADS)

    Plassard, Andrew; Hinton, Kendra E.; Venkatraman, Vijay; Gonzalez, Christopher; Resnick, Susan M.; Landman, Bennett A.

    2015-03-01

    Multi-atlas labeling has come in wide spread use for whole brain labeling on magnetic resonance imaging. Recent challenges have shown that leading techniques are near (or at) human expert reproducibility for cortical gray matter labels. However, these approaches tend to treat white matter as essentially homogeneous (as white matter exhibits isointense signal on structural MRI). The state-of-the-art for white matter atlas is the single-subject Johns Hopkins Eve atlas. Numerous approaches have attempted to use tractography and/or orientation information to identify homologous white matter structures across subjects. Despite success with large tracts, these approaches have been plagued by difficulties in with subtle differences in course, low signal to noise, and complex structural relationships for smaller tracts. Here, we investigate use of atlas-based labeling to propagate the Eve atlas to unlabeled datasets. We evaluate single atlas labeling and multi-atlas labeling using synthetic atlases derived from the single manually labeled atlas. On 5 representative tracts for 10 subjects, we demonstrate that (1) single atlas labeling generally provides segmentations within 2mm mean surface distance, (2) morphologically constraining DTI labels within structural MRI white matter reduces variability, and (3) multi-atlas labeling did not improve accuracy. These efforts present a preliminary indication that single atlas labels with correction is reasonable, but caution should be applied. To purse multi-atlas labeling and more fully characterize overall performance, more labeled datasets would be necessary.

  11. Evaluation of Atlas-Based White Matter Segmentation with Eve.

    PubMed

    Plassard, Andrew J; Hinton, Kendra E; Venkatraman, Vijay; Gonzalez, Christopher; Resnick, Susan M; Landman, Bennett A

    2015-03-20

    Multi-atlas labeling has come in wide spread use for whole brain labeling on magnetic resonance imaging. Recent challenges have shown that leading techniques are near (or at) human expert reproducibility for cortical gray matter labels. However, these approaches tend to treat white matter as essentially homogeneous (as white matter exhibits isointense signal on structural MRI). The state-of-the-art for white matter atlas is the single-subject Johns Hopkins Eve atlas. Numerous approaches have attempted to use tractography and/or orientation information to identify homologous white matter structures across subjects. Despite success with large tracts, these approaches have been plagued by difficulties in with subtle differences in course, low signal to noise, and complex structural relationships for smaller tracts. Here, we investigate use of atlas-based labeling to propagate the Eve atlas to unlabeled datasets. We evaluate single atlas labeling and multi-atlas labeling using synthetic atlases derived from the single manually labeled atlas. On 5 representative tracts for 10 subjects, we demonstrate that (1) single atlas labeling generally provides segmentations within 2mm mean surface distance, (2) morphologically constraining DTI labels within structural MRI white matter reduces variability, and (3) multi-atlas labeling did not improve accuracy. These efforts present a preliminary indication that single atlas labels with correction is reasonable, but caution should be applied. To purse multi-atlas labeling and more fully characterize overall performance, more labeled datasets would be necessary.

  12. Robust estimation of fractal measures for characterizing the structural complexity of the human brain: optimization and reproducibility

    PubMed Central

    Goñi, Joaquín; Sporns, Olaf; Cheng, Hu; Aznárez-Sanado, Maite; Wang, Yang; Josa, Santiago; Arrondo, Gonzalo; Mathews, Vincent P; Hummer, Tom A; Kronenberger, William G; Avena-Koenigsberger, Andrea; Saykin, Andrew J.; Pastor, María A.

    2013-01-01

    High-resolution isotropic three-dimensional reconstructions of human brain gray and white matter structures can be characterized to quantify aspects of their shape, volume and topological complexity. In particular, methods based on fractal analysis have been applied in neuroimaging studies to quantify the structural complexity of the brain in both healthy and impaired conditions. The usefulness of such measures for characterizing individual differences in brain structure critically depends on their within-subject reproducibility in order to allow the robust detection of between-subject differences. This study analyzes key analytic parameters of three fractal-based methods that rely on the box-counting algorithm with the aim to maximize within-subject reproducibility of the fractal characterizations of different brain objects, including the pial surface, the cortical ribbon volume, the white matter volume and the grey matter/white matter boundary. Two separate datasets originating from different imaging centers were analyzed, comprising, 50 subjects with three and 24 subjects with four successive scanning sessions per subject, respectively. The reproducibility of fractal measures was statistically assessed by computing their intra-class correlations. Results reveal differences between different fractal estimators and allow the identification of several parameters that are critical for high reproducibility. Highest reproducibility with intra-class correlations in the range of 0.9–0.95 is achieved with the correlation dimension. Further analyses of the fractal dimensions of parcellated cortical and subcortical gray matter regions suggest robustly estimated and region-specific patterns of individual variability. These results are valuable for defining appropriate parameter configurations when studying changes in fractal descriptors of human brain structure, for instance in studies of neurological diseases that do not allow repeated measurements or for disease-course longitudinal studies. PMID:23831414

  13. Prospective Science Teachers' Subject-Matter Knowledge about Overflow Container

    ERIC Educational Resources Information Center

    Ültay, Eser

    2016-01-01

    The purpose of this study was to determine prospective science teachers' subject-matter knowledge (SMK) about overflow container. This study was carried out in the form of a case study in spring term of the academic year of 2013-2014 with seven sophomore prospective science teachers who were studying at Elementary Science Teaching Department in…

  14. Subject-Matter Experts in Urban Schools: Journeys of Enacted Identities in Science and Mathematics Classrooms

    ERIC Educational Resources Information Center

    Ye, Li; Varelas, Maria; Guajardo, Raphael

    2011-01-01

    This study explored how two mathematics/science subject-matter experts (Fellows) conceptualized urban classrooms and the students they worked with for a year, how they negotiated academic achievement with cultural and sociopolitical competence, and how their identities as educators were co-constructed and enacted. Using grounded theory, Fellows'…

  15. How a Deweyan Science Education Further Enables Ethics Education

    ERIC Educational Resources Information Center

    Webster, Scott

    2008-01-01

    This paper questions the perceived divide between "science" subject matter and "moral" or "ethical" subject matter. A difficulty that this assumed divide produces is that science teachers often feel that there needs to be "special treatment" given to certain issues which are of an ethical or moral nature and which are "brought into" the science…

  16. Biology Teachers' Perceptions of Subject Matter Structure and Its Relationship to Classroom Practice.

    ERIC Educational Resources Information Center

    Gess-Newsome, Julie; Lederman, Norman G.

    Current reform efforts in the teaching of high school biology demonstrate the need for a synthetic treatment of prominent concepts. There exists insufficient research that delineates the global content understandings--in this paper designated subject matter structures (SMS)--of biology teachers; or that assesses whether these SMS do, in fact,…

  17. Opinion: The Two Subject Matters of Behavior Analysis and Early Intervention

    ERIC Educational Resources Information Center

    Greer, R. Douglas

    2004-01-01

    The author argues that the field of behavior intervention has two subject matters that are distinct in several ways. Each is derived from, and contributes to, the foundation science and epistemology associated with behavior selection. The differences that the author wants to describe occurred to him as he sought to identify which of two Spanish…

  18. The Representation of Reality in Teaching: A "Mimetic Didactic" Perspective on Examples in Plenary Talk

    ERIC Educational Resources Information Center

    Willbergh, Ilmi

    2017-01-01

    Using an observation study in Norwegian lower-secondary school classrooms this paper explores how subject matter and students' real-world experiences are linked within the use of examples in teaching. The theory of "mimetic didactics" claims that giving students the possibility to interpret examples as both subject matter and something…

  19. The Role of Subject-Matter Content in Teacher Preparation: An International Perspective for Mathematics

    ERIC Educational Resources Information Center

    Schmidt, William H.; Burroughs, Nathan A.; Cogan, Leland S.; Houang, Richard T.

    2017-01-01

    International comparative studies in education provide a fresh perspective on K-12 education policy by enabling countries to learn from each other's approaches. The recently conducted Teacher Education and Development Study--Mathematics provides a worldwide lens by which to examine the role of subject-matter in the preparation of US teachers of…

  20. Multilingual Writing in an Age of Accountability: From Policy to Practice in U.S. High School Classrooms

    ERIC Educational Resources Information Center

    Enright, Kerry Anne; Gilliland, Betsy

    2011-01-01

    This article considers the influence of the U.S. accountability- and standards-driven context on the writing experiences of multilingual writers in "New Mainstream" linguistically diverse high school classrooms. Qualitative data from 12 ninth grade subject-matter classes were examined to note how uses of writing in subject-matter classrooms…

  1. Not What They Want, but What They Need: Teaching Politics to Journalism Students

    ERIC Educational Resources Information Center

    Clark, Tor; Jones, Alistair

    2017-01-01

    There is an issue around getting students engaged in subject matter about which they may have little interest. Often, such subject matter is essential to their studies. The module Essential Public Affairs is such a concern for students of journalism. It is essential for their professional qualification. This article explores a pilot project which…

  2. Exemplar: A Model for Social Studies Curriculum Development in Delaware, K-12.

    ERIC Educational Resources Information Center

    Delaware State Dept. of Public Instruction, Dover.

    GRADES OR AGES: Grades K-12. SUBJECT MATTER: Social studies. ORGANIZATION AND PHYSICAL APPEARANCE: The subject matter is divided into the following five themes: 1) Man develops within his physical and cultural environment. 2) Man functions within an interdependent society. 3) Man seeks justice and order. 4) Man experiences conflict and change. 5)…

  3. On the Importance of Subject Matter in Mathematics Education: A Conversation with Erich Christian Wittmann

    ERIC Educational Resources Information Center

    Akinwunmi, Kathrin; Höveler, Karina; Schnell, Susanne

    2014-01-01

    Erich Christian Wittmann is one of the primary founders of mathematics education research as an autonomous field of work and research in Germany. The interview presented here reflects on his role in promoting mathematics education as a design science. The interview addresses the following topics: (1) The importance of subject matter in…

  4. Student-Student Online Coaching: Conceptualizing an Emerging Learning Activity

    ERIC Educational Resources Information Center

    Hrastinski, Stefan; Stenbom, Stefan

    2013-01-01

    The aim of this paper is to describe student-student online coaching, defined as "an online service where a student gets support on a specific subject matter from a more experienced student". Student-student online coaching emphasizes learning a subject matter by giving a student the opportunity to get coached by a coach, i.e. a more experienced…

  5. Subject Matter in Hong Kong Primary English Classrooms: A Critical Analysis of Teacher Talk

    ERIC Educational Resources Information Center

    He, An

    2006-01-01

    Studies of language issues in postcolonial Hong Kong are abundant. While the majority is concerned with the language policy and medium of instruction, there seems to be insufficient discussion on the subject matter of our English lessons, which, this paper argues, are ideology-ridden. Following the tradition of critical discourse analysis and…

  6. Do School Counselors Matter? Mattering as a Moderator between Job Stress and Job Satisfaction

    ERIC Educational Resources Information Center

    Rayle, Andrea Dixon

    2006-01-01

    The relationships of perceived mattering to others, job-related stress, and job satisfaction were examined for 388 elementary, middle, and high school counselors from across the United States. Participants completed the School Counselor Mattering Scale, the School Counselor Job-Stress Assessment, and several job satisfaction questions in order to…

  7. Lecturing skills as predictors of tutoring skills in a problem-based medical curriculum.

    PubMed

    Kassab, Salah Eldin; Hassan, Nahla; Abu-Hijleh, Marwan F; Sequeira, Reginald P

    2016-01-01

    Recruitment of tutors to work in problem-based learning (PBL) programs is challenging, especially in that most of them are graduated from discipline-based programs. Therefore, this study aims at examining whether lecturing skills of faculty could predict their PBL tutoring skills. This study included evaluation of faculty (n=69) who participated in both tutoring and lecturing within particular PBL units at the College of Medicine and Medical Sciences (CMMS), Arabian Gulf University, Bahrain. Each faculty was evaluated by medical students (n=45±8 for lecturing and 8±2 for PBL tutoring) using structured evaluation forms based on a Likert-type scale (poor to excellent). The prediction of tutoring skills using lecturing skills was statistically analyzed using stepwise linear regression. Among the parameters used to judge lecturing skills, the most important predictor for tutoring skills was subject matter mastery in the lecture by explaining difficult concepts and responding effectively to students' questions. Subject matter mastery in the lecture positively predicted five tutoring skills and accounted for 25% of the variance in overall effectiveness of the PBL tutors (F=22.39, P=0.000). Other important predictors for tutoring skills were providing a relaxed class atmosphere and effective use of audiovisual aids in the lecture. Predicting the tutoring skills based on lecturing skills could have implications for recruiting tutors in PBL medical programs and for tutor training initiatives.

  8. Particulate Matter Stack Emission Compliance Test Procedure for Fuel Burning Units.

    ERIC Educational Resources Information Center

    West Virginia Air Pollution Control Commission, Charleston.

    This publication details the particulate matter emissions test procedure that is applicable for conducting compliance tests for fuel burning units required to be tested under Sub-section 7 of Regulation II (1972) as established by the state of West Virginia Air Pollution Control Commission. The testing procedure is divided into five parts:…

  9. 78 FR 16894 - In the Matter of Luminant Generation Company LLC, Comanche Peak Nuclear Power Plant, Units 1 and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-19

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0310; Docket Nos.: 50-445 and 50-446; License Nos.: NPF-87 and NPF-89] In the Matter of Luminant Generation Company LLC, Comanche Peak Nuclear Power Plant, Units 1 and 2; Order Approving the Proposed Internal Restructuring and Indirect Transfer of License...

  10. 37 CFR 11.14 - Individuals who may practice before the Office in trademark and other non-patent matters.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... before the Office in trademark and other non-patent matters. 11.14 Section 11.14 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE REPRESENTATION OF OTHERS BEFORE THE UNITED STATES PATENT AND TRADEMARK OFFICE Recognition To Practice Before the USPTO Patents...

  11. 37 CFR 11.14 - Individuals who may practice before the Office in trademark and other non-patent matters.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... before the Office in trademark and other non-patent matters. 11.14 Section 11.14 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE REPRESENTATION OF OTHERS BEFORE THE UNITED STATES PATENT AND TRADEMARK OFFICE Recognition To Practice Before the USPTO Patents...

  12. 37 CFR 11.14 - Individuals who may practice before the Office in trademark and other non-patent matters.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... before the Office in trademark and other non-patent matters. 11.14 Section 11.14 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE REPRESENTATION OF OTHERS BEFORE THE UNITED STATES PATENT AND TRADEMARK OFFICE Recognition To Practice Before the USPTO Patents...

  13. 37 CFR 11.14 - Individuals who may practice before the Office in trademark and other non-patent matters.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... before the Office in trademark and other non-patent matters. 11.14 Section 11.14 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE REPRESENTATION OF OTHERS BEFORE THE UNITED STATES PATENT AND TRADEMARK OFFICE Recognition To Practice Before the USPTO Patents...

  14. Individualized Instruction in Science, Time-Space-Matter, Learning Activity Packages.

    ERIC Educational Resources Information Center

    Kuczma, R. M.

    Learning Activity Packages (LAP) relating to time, space, and matter are presented for use in sampling a new type of learning for a whole year. Besides the unit on introduction to individualized learning, 11 major topics are incorporated into three other units: (1) observation of the physical world, (2) space and exploration for environmental…

  15. 43 CFR 4.1132 - Scope of discovery.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., the parties may obtain discovery regarding any matter, not privileged, which is relevant to the subject matter involved in the proceeding, including the existence, description, nature, custody... persons having knowledge of any discoverable matter. (b) It is not ground for objection that information...

  16. 43 CFR 4.1132 - Scope of discovery.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., the parties may obtain discovery regarding any matter, not privileged, which is relevant to the subject matter involved in the proceeding, including the existence, description, nature, custody... persons having knowledge of any discoverable matter. (b) It is not ground for objection that information...

  17. 43 CFR 4.1132 - Scope of discovery.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., the parties may obtain discovery regarding any matter, not privileged, which is relevant to the subject matter involved in the proceeding, including the existence, description, nature, custody... persons having knowledge of any discoverable matter. (b) It is not ground for objection that information...

  18. 43 CFR 4.1132 - Scope of discovery.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., the parties may obtain discovery regarding any matter, not privileged, which is relevant to the subject matter involved in the proceeding, including the existence, description, nature, custody... persons having knowledge of any discoverable matter. (b) It is not ground for objection that information...

  19. Large CSF Volume Not Attributable to Ventricular Volume in Schizotypal Personality Disorder

    PubMed Central

    Dickey, Chandlee C.; Shenton, Martha E.; Hirayasu, Yoshio; Fischer, Iris; Voglmaier, Martina M.; Niznikiewicz, Margaret A.; Seidman, Larry J.; Fraone, Stephanie; McCarley, Robert W.

    2010-01-01

    Objective The purpose of this study was to determine whether schizotypal personality disorder, which has the same genetic diathesis as schizophrenia, manifests abnormalities in whole-brain and CSF volumes. Method Sixteen right-handed and neuroleptic-naive men with schizotypal personality disorder were recruited from the community and were age-matched to 14 healthy comparison subjects. Magnetic resonance images were obtained from the subjects and automatically parcellated into CSF, gray matter, and white matter. Subsequent manual editing separated cortical from noncortical gray matter. Lateral ventricles and temporal horns were also delineated. Results The men with schizotypal personality disorder had larger CSF volumes than the comparison subjects; the difference was not attributable to larger lateral ventricles. The cortical gray matter was somewhat smaller in the men with schizotypal personality disorder, but the difference was not statistically significant. Conclusions Consistent with many studies of schizophrenia, this examination of schizotypal personality disorder indicated abnormalities in brain CSF volumes. PMID:10618012

  20. 45 CFR 1.2 - Subject matter of Office of the Secretary regulations in parts 1-99.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... subject matter of the regulations in Parts 1-99 of this title includes: • Civil rights/nondiscrimination... regulations in parts 1-99. 1.2 Section 1.2 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL.... • Grants and letter of credit administration, property, hearing rights: Parts 10, 12, 15, 16, 74, 75, 77...

  1. 45 CFR 1.2 - Subject matter of Office of the Secretary regulations in parts 1-99.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... subject matter of the regulations in Parts 1-99 of this title includes: • Civil rights/nondiscrimination... regulations in parts 1-99. 1.2 Section 1.2 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL.... • Grants and letter of credit administration, property, hearing rights: Parts 10, 12, 15, 16, 74, 75, 77...

  2. 45 CFR 1.2 - Subject matter of Office of the Secretary regulations in parts 1-99.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... subject matter of the regulations in Parts 1-99 of this title includes: • Civil rights/nondiscrimination... regulations in parts 1-99. 1.2 Section 1.2 Public Welfare Department of Health and Human Services GENERAL.... • Grants and letter of credit administration, property, hearing rights: Parts 10, 12, 15, 16, 74, 75, 77...

  3. Teachers' Subject Matter Knowledge as a Teacher Qualification: A Synthesis of the Quantitative Literature on Students' Mathematics Achievement

    ERIC Educational Resources Information Center

    Ahn, Soyeon; Choi, Jinyoung

    2004-01-01

    The aim of this paper is to examine a variety of features of research that might account for mixed findings of the relationship between teachers' subject matter knowledge and student achievement based on meta-analytic technique. Of several variables that might contribute to inconsistencies and variations in study findings, three features of…

  4. An Examination of Preschool Prospective Teachers' Subject Matter Knowledge and Pedagogical Content Knowledge on Basic Geometric Shapes in Turkey

    ERIC Educational Resources Information Center

    Canturk-Gunhan, Berna; Cetingoz, Duygu

    2013-01-01

    The purpose of this study is to examine preschool preservice teachers' subject matter knowledge (SMK) and pedagogical content knowledge (PCK) of basic geometric shapes. The study employed case study method in order to investigate preschool preservice teachers' SMK and PCK on geometric shapes in actual classroom environment and to describe the…

  5. Developing Pre-Service Teachers' Subject Matter Knowledge of Electromagnetism by Integrating Concept Maps and Collaborative Learning

    ERIC Educational Resources Information Center

    Govender, Nadaraj

    2015-01-01

    This case study explored the development of two pre-service teachers' subject matter knowledge (SMK) of electromagnetism while integrating the use of concept maps (CM) and collaborative learning (CL) strategies. The study aimed at capturing how these pre-service teachers' SMK in electromagnetism was enhanced after having been taught SMK in a…

  6. Cooperative Health Occupation Education (Course Outline), Body Structure and Function II: 8009.09.

    ERIC Educational Resources Information Center

    Dade County Public Schools, Miami, FL.

    GRADES OR AGES: Grade Twelve. SUBJECT MATTER: This is the second part of a two-part course on body structure and function. The subject matter includes organization, composition, and all the systems of the human body. Laboratory experiments related to first aid are also covered. ORGANIZATION AND PHYSICAL APPEARANCE: The guide contains a preface, a…

  7. Factorial Validity of a Questionnaire to Evaluate University Students' Initial Perception of Learning Evaluation

    ERIC Educational Resources Information Center

    Doménech-Betoret, Fernando; Fortea-Bagán, Miguel Angel

    2015-01-01

    Introduction: Education research has clearly verified that a student's perception of the system to evaluate the subject matter will play a fundamental role in his/her implication (deep approach vs. surface approach) in the teaching/learning process of the subject matter. The present work aims to examine the factorial validity and reliability of a…

  8. Development of Syntactic Subject Matter Knowledge and Pedagogical Content Knowledge for Science by a Generalist Elementary Teacher

    ERIC Educational Resources Information Center

    Anderson, Dayle; Clark, Megan

    2012-01-01

    The nature of knowledge needed for teaching elementary science and the development of such knowledge is a focus of ongoing research in science education. Internationally, there is a move to include scientific literacy as an aim of science education curricula. In order to teach such curricula teachers need two types of subject matter knowledge…

  9. The Designer-by-Assignment in Practice: Instructional Design Thinking of Subject Matter Experts

    ERIC Educational Resources Information Center

    Pesce, Sandra V.

    2012-01-01

    Designers-by-assignment, or subject matter experts (SMEs) who are pressed into training service, have become common in the workplace. A review of more than 24 studies on expert and novice instructional designers, however, revealed that little is known about how designers-by-assignment think about design and make design decisions in the field. A…

  10. The Knowledge Base of Subject Matter Experts in Teaching: A Case Study of a Professional Scientist as a Beginning Teacher

    ERIC Educational Resources Information Center

    Diezmann, Carmel M.; Watters, James J.

    2015-01-01

    One method of addressing the shortage of science and mathematics teachers is to train scientists and other science-related professionals to become teachers. Advocates argue that as discipline experts these career changers can relate the subject matter knowledge to various contexts and applications in teaching. In this paper, through interviews and…

  11. The Correlation between Prospective Teachers' Knowledge of Algebraic Inverse Operations and Teaching Competency--Using the Square Root as an Example

    ERIC Educational Resources Information Center

    Leung, Issic Kui Chiu; Ding, Lin; Leung, Allen Yuk Lun; Wong, Ngai Ying

    2016-01-01

    This study is part of a larger study investigating the subject matter knowledge and pedagogical content knowledge of Hong Kong prospective mathematics teachers, the relationship between the knowledge of algebraic operation and its inverse, and their teaching competency. In this paper, we address the subject matter knowledge and pedagogical content…

  12. Exploring the Impact of a Standards-Based Mathematics and Pedagogy Class on Preservice Teachers' Beliefs and Subject Matter Knowledge

    ERIC Educational Resources Information Center

    Stohlmann, Micah Stephen

    2012-01-01

    This case study explored the impact of a standards-based mathematics and pedagogy class on preservice elementary teachers' beliefs and conceptual subject matter knowledge of linear functions. The framework for the standards-based mathematics and pedagogy class in this study involved the National Council of Teachers of Mathematics Standards,…

  13. Pre-Reading Materials from Subject Matter Texts--Learner Choices and the Underlying Learner Characteristics

    ERIC Educational Resources Information Center

    Huang, Shu-Chen; Cheng, Yuh-Show; Chern, Chiou-Lan

    2006-01-01

    In this study, attempts were made to design pre-reading materials for EAP reading using resources available from the subject matter texts. These materials were considered more facilitative in motivating learners to read and helping them to understand rather than to decode the texts. EFL college participants read three articles with three types of…

  14. Is Practical Subject Matter Knowledge Still Important? Examining the Siedentopian Perspective on the Role of Content Knowledge in Physical Education Teacher Education

    ERIC Educational Resources Information Center

    Herold, Frank; Waring, Michael

    2017-01-01

    Background: The role that content knowledge, an important component of practical subject matter knowledge, plays for pre-service teachers (PSTs) in physical education teacher education (PETE) remains contested and unclear. Whilst some researchers emphasise the facilitative nature of such knowledge, others criticise that too much focus on content…

  15. Exploring the Relationship between Secondary Science Teachers' Subject Matter Knowledge and Knowledge of Student Conceptions While Teaching Evolution by Natural Selection

    ERIC Educational Resources Information Center

    Lucero, Margaret M.; Petrosino, Anthony J.; Delgado, Cesar

    2017-01-01

    The fundamental scientific concept of evolution occurring by natural selection is home to many deeply held alternative conceptions and considered difficult to teach. Science teachers' subject matter knowledge (SMK) and the pedagogical content knowledge (PCK) component of knowledge of students' conceptions (KOSC) can be valuable resources for…

  16. Nielsen's "Befindlichkeit" between (The Hermeneutics of) "Bildung" and (The Phenomenology of) Music

    ERIC Educational Resources Information Center

    Frederik, Pio

    2014-01-01

    Among other things, the work of Frede Nielsen gradually took the form of an analytical clarification of the integration between subject matter and pedagogy; in other words, how the reciprocal relation between musical subject matter and pedagogy can be unfolded in an inner (that is nondualist) state of things? This issue is ascribed key importance…

  17. White matter deficits assessed by diffusion tensor imaging and cognitive dysfunction in psychostimulant users with comorbid human immunodeficiency virus infection.

    PubMed

    Tang, Victor M; Lang, Donna J; Giesbrecht, Chantelle J; Panenka, William J; Willi, Taylor; Procyshyn, Ric M; Vila-Rodriguez, Fidel; Jenkins, Willough; Lecomte, Tania; Boyda, Heidi N; Aleksic, Ana; MacEwan, G William; Honer, William G; Barr, Alasdair M

    2015-09-30

    Psychostimulant drug use is commonly associated with drug-related infection, including the human immunodeficiency virus (HIV). Both psychostimulant use and HIV infection are known to damage brain white matter and impair cognition. To date, no study has examined white matter integrity using magnetic resonance imaging (MRI) diffusion tensor imaging (DTI) in chronic psychostimulant users with comorbid HIV infection, and determined the relationship of white matter integrity to cognitive function. Twenty-one subjects (mean age 37.5 ± 9.0 years) with a history of heavy psychostimulant use and HIV infection (8.7 ± 4.3 years) and 22 matched controls were scanned on a 3T MRI. Fractional anisotropy (FA) values were calculated with DTI software. Four regions of interest were manually segmented, including the genu of the corpus callosum, left and right anterior limbs of the internal capsule, and the anterior commissure. Subjects also completed a neurocognitive battery and questionnaires about physical and mental health. The psychostimulant using, HIV positive group displayed decreased white matter integrity, with significantly lower FA values for all white matter tracts (p < 0.05). This group also exhibited decreased cognitive performance on tasks that assessed cognitive set-shifting, fine motor speed and verbal memory. FA values for the white matter tracts correlated with cognitive performance on many of the neurocognitive tests. White matter integrity was thus impaired in subjects with psychostimulant use and comorbid HIV infection, which predicted worsened cognitive performance on a range of tests. Further study on this medical comorbidity is required.

  18. White matter integrity as a predictor of response to treatment in first episode psychosis.

    PubMed

    Reis Marques, Tiago; Taylor, Heather; Chaddock, Chris; Dell'acqua, Flavio; Handley, Rowena; Reinders, A A T Simone; Mondelli, Valeria; Bonaccorso, Stefania; Diforti, Marta; Simmons, Andrew; David, Anthony S; Murray, Robin M; Pariante, Carmine M; Kapur, Shitij; Dazzan, Paola

    2014-01-01

    The integrity of brain white matter connections is central to a patient's ability to respond to pharmacological interventions. This study tested this hypothesis using a specific measure of white matter integrity, and examining its relationship to treatment response using a prospective design in patients within their first episode of psychosis. Diffusion tensor imaging data were acquired in 63 patients with first episode psychosis and 52 healthy control subjects (baseline). Response was assessed after 12 weeks and patients were classified as responders or non-responders according to treatment outcome. At this second time-point, they also underwent a second diffusion tensor imaging scan. Tract-based spatial statistics were used to assess fractional anisotropy as a marker of white matter integrity. At baseline, non-responders showed lower fractional anisotropy than both responders and healthy control subjects (P < 0.05; family-wise error-corrected), mainly in the uncinate, cingulum and corpus callosum, whereas responders were indistinguishable from healthy control subjects. After 12 weeks, there was an increase in fractional anisotropy in both responders and non-responders, positively correlated with antipsychotic exposure. This represents one of the largest, controlled investigations of white matter integrity and response to antipsychotic treatment early in psychosis. These data, together with earlier findings on cortical grey matter, suggest that grey and white matter integrity at the start of treatment is an important moderator of response to antipsychotics. These findings can inform patient stratification to anticipate care needs, and raise the possibility that antipsychotics may restore white matter integrity as part of the therapeutic response.

  19. White matter fiber integrity of the saccadic eye movement network differs between schizophrenia and healthy groups.

    PubMed

    Schaeffer, David J; Rodrigue, Amanda L; Burton, Courtney R; Pierce, Jordan E; Murphy, Megan N; Clementz, Brett A; McDowell, Jennifer E

    2017-12-01

    Recent diffusion tensor imaging (DTI) studies suggest that altered white matter fiber integrity is a pathophysiological feature of schizophrenia. Lower white matter integrity is associated with poor cognitive control, a characteristic of schizophrenia that can be measured using antisaccade tasks. Although the functional neural correlates of poor antisaccade performance have been well documented, fewer studies have investigated the extent to which white matter fibers connecting the functional nodes of this network contribute to antisaccade performance. The aim of the present study was to assess the white matter structural integrity of fibers connecting two functional nodes (putamen and medial frontal eye fields) of the saccadic eye movement network implicated in poor antisaccade performance in schizophrenia. To evaluate white matter integrity, DTI was acquired on subjects with schizophrenia and two comparison groups: (a) behaviorally matched healthy comparison subjects with low levels of cognitive control (LCC group), and (b) healthy subjects with high levels of cognitive control (HCC group). White matter fibers were tracked between functional regions of interest generated from antisaccade fMRI activation maps, and measures of diffusivity were quantified. The results demonstrated lower white matter integrity in the schizophrenia group than in the HCC group, but not the LCC group who showed similarly poor cognitive control performance. Overall, the results suggest that these alterations are not specific to the disease process of schizophrenia, but may rather be a function of uncontrolled cognitive factors that are concomitant with the disease but also observed in some healthy people. © 2017 Society for Psychophysiological Research.

  20. 16 CFR 1025.31 - General provisions governing discovery.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...: (1) In general. Parties may obtain discovery regarding any matter, not privileged, which is within the Commission's statutory authority and is relevant to the subject matter involved in the proceedings... any discoverable matter. It is not ground for objection that the information sought will be...

  1. 16 CFR 1025.31 - General provisions governing discovery.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...: (1) In general. Parties may obtain discovery regarding any matter, not privileged, which is within the Commission's statutory authority and is relevant to the subject matter involved in the proceedings... any discoverable matter. It is not ground for objection that the information sought will be...

  2. 16 CFR 1025.31 - General provisions governing discovery.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...: (1) In general. Parties may obtain discovery regarding any matter, not privileged, which is within the Commission's statutory authority and is relevant to the subject matter involved in the proceedings... any discoverable matter. It is not ground for objection that the information sought will be...

  3. The white matter query language: a novel approach for describing human white matter anatomy

    PubMed Central

    Makris, Nikos; Rathi, Yogesh; Shenton, Martha; Kikinis, Ron; Kubicki, Marek; Westin, Carl-Fredrik

    2016-01-01

    We have developed a novel method to describe human white matter anatomy using an approach that is both intuitive and simple to use, and which automatically extracts white matter tracts from diffusion MRI volumes. Further, our method simplifies the quantification and statistical analysis of white matter tracts on large diffusion MRI databases. This work reflects the careful syntactical definition of major white matter fiber tracts in the human brain based on a neuroanatomist’s expert knowledge. The framework is based on a novel query language with a near-to-English textual syntax. This query language makes it possible to construct a dictionary of anatomical definitions that describe white matter tracts. The definitions include adjacent gray and white matter regions, and rules for spatial relations. This novel method makes it possible to automatically label white matter anatomy across subjects. After describing this method, we provide an example of its implementation where we encode anatomical knowledge in human white matter for ten association and 15 projection tracts per hemisphere, along with seven commissural tracts. Importantly, this novel method is comparable in accuracy to manual labeling. Finally, we present results applying this method to create a white matter atlas from 77 healthy subjects, and we use this atlas in a small proof-of-concept study to detect changes in association tracts that characterize schizophrenia. PMID:26754839

  4. The white matter query language: a novel approach for describing human white matter anatomy.

    PubMed

    Wassermann, Demian; Makris, Nikos; Rathi, Yogesh; Shenton, Martha; Kikinis, Ron; Kubicki, Marek; Westin, Carl-Fredrik

    2016-12-01

    We have developed a novel method to describe human white matter anatomy using an approach that is both intuitive and simple to use, and which automatically extracts white matter tracts from diffusion MRI volumes. Further, our method simplifies the quantification and statistical analysis of white matter tracts on large diffusion MRI databases. This work reflects the careful syntactical definition of major white matter fiber tracts in the human brain based on a neuroanatomist's expert knowledge. The framework is based on a novel query language with a near-to-English textual syntax. This query language makes it possible to construct a dictionary of anatomical definitions that describe white matter tracts. The definitions include adjacent gray and white matter regions, and rules for spatial relations. This novel method makes it possible to automatically label white matter anatomy across subjects. After describing this method, we provide an example of its implementation where we encode anatomical knowledge in human white matter for ten association and 15 projection tracts per hemisphere, along with seven commissural tracts. Importantly, this novel method is comparable in accuracy to manual labeling. Finally, we present results applying this method to create a white matter atlas from 77 healthy subjects, and we use this atlas in a small proof-of-concept study to detect changes in association tracts that characterize schizophrenia.

  5. Localizing gray matter deficits in late-onset depression using computational cortical pattern matching methods.

    PubMed

    Ballmaier, Martina; Kumar, Anand; Thompson, Paul M; Narr, Katherine L; Lavretsky, Helen; Estanol, Laverne; Deluca, Heather; Toga, Arthur W

    2004-11-01

    The authors used magnetic resonance imaging and an image analysis technique known as cortical pattern matching to map cortical gray matter deficits in elderly depressed patients with an illness onset after age 60 (late-onset depression). Seventeen patients with late-onset depression (11 women and six men; mean age=75.24, SD=8.52) and 17 group-matched comparison subjects (11 women and six men; mean age=73.88, SD=7.61) were included. Detailed spatial analyses of gray matter were conducted across the entire cortex by measuring local proportions of gray matter at thousands of homologous cortical surface locations in each subject, and these patterns were matched across subjects by using elastic transformations to align sulcal topography. To visualize regional changes, statistical differences were mapped at each cortical surface location in three dimensions. The late-onset depression group exhibited significant gray matter deficits in the right lateral temporal cortex and the right parietal cortex, where decreases were most pronounced in sensorimotor regions. The statistical maps also showed gray matter deficits in the same regions of the left hemisphere that approached significance after permutation testing. No significant group differences were detected in frontal cortices or any other anatomical region. Regionally specific decreases of gray matter occur in late-onset depression, supporting the hypothesis that this subset of elderly patients with major depression presents with certain unique neuroanatomical abnormalities that may differ from patients with an earlier onset of illness.

  6. 77 FR 31691 - Approval and Promulgation of Implementation Plans; State of Hawaii; Regional Haze Federal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-29

    ... Subject to BART 3. BART Determination for Kanoelehua Hill a. BART for NO X and Particulate Matter (PM) b.... The initials PM mean or refer to particulate matter. xxiv. The initials PM2.5 mean or refer to particulate matter with an aerodynamic diameter of less than 2.5 micrometers (fine particulate matter). xxv...

  7. 40 CFR 72.20 - Authorization and responsibilities of the designated representative.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... representative, with regard to all matters under the Acid Rain Program concerning the source or any affected unit... affected unit at the source in all matters pertaining to the Acid Rain Program, not withstanding any... certifications set forth in § 72.24(a) (4), (5), (7), and (9). (d) No Acid Rain permit shall be issued to an...

  8. 40 CFR 72.20 - Authorization and responsibilities of the designated representative.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... representative, with regard to all matters under the Acid Rain Program concerning the source or any affected unit... affected unit at the source in all matters pertaining to the Acid Rain Program, not withstanding any... certifications set forth in § 72.24(a) (4), (5), (7), and (9). (d) No Acid Rain permit shall be issued to an...

  9. 40 CFR 72.20 - Authorization and responsibilities of the designated representative.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... representative, with regard to all matters under the Acid Rain Program concerning the source or any affected unit... affected unit at the source in all matters pertaining to the Acid Rain Program, not withstanding any... certifications set forth in § 72.24(a) (4), (5), (7), and (9). (d) No Acid Rain permit shall be issued to an...

  10. 40 CFR 72.20 - Authorization and responsibilities of the designated representative.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... representative, with regard to all matters under the Acid Rain Program concerning the source or any affected unit... affected unit at the source in all matters pertaining to the Acid Rain Program, not withstanding any... certifications set forth in § 72.24(a) (4), (5), (7), and (9). (d) No Acid Rain permit shall be issued to an...

  11. 40 CFR 72.20 - Authorization and responsibilities of the designated representative.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... representative, with regard to all matters under the Acid Rain Program concerning the source or any affected unit... affected unit at the source in all matters pertaining to the Acid Rain Program, not withstanding any... certifications set forth in § 72.24(a) (4), (5), (7), and (9). (d) No Acid Rain permit shall be issued to an...

  12. 77 FR 74186 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-13

    ..., Consumer Financial Protection Bureau), and Chairman Martin J. Gruenberg, that Corporation business required its consideration of the matters which were to be the subject of this meeting on less than seven days... not require consideration of the matters in a meeting open to public observation; and that the matters...

  13. Should biochar be used in container substrates?

    USDA-ARS?s Scientific Manuscript database

    Biochar is charred organic matter that remains after a process called pyrolysis. Pyrolysis is a thermochemical decomposition of organic matter. In this process, organic matter is subjected to extremely high temperatures (200 to 800 °C) in the absence of oxygen. The history of biochar use begins i...

  14. 76 FR 78054 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-15

    .... Certain staff members who have an interest in the matters also may be present. The General Counsel of the...), permit consideration of the scheduled matters at the Closed Meeting. Commissioner Paredes, as duty... subject matter of the Closed Meeting scheduled for Monday, December 19, 2011 will be: Institution and...

  15. 77 FR 66658 - Sunshine Act Meeting Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-06

    ... Closed Meeting. Certain staff members who have an interest in the matters also may be present. The...) and (10), permit consideration of the scheduled matters at the Closed Meeting. Commissioner Gallagher... subject matter of the Closed Meeting scheduled for Thursday, November 8, 2012 will be: Institution and...

  16. 29 CFR 18.14 - Scope of discovery.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... administrative law judge in accordance with these rules, the parties may obtain discovery regarding any matter, not privileged, which is relevant to the subject matter involved in the proceeding, including the... things and the identity and location of persons having knowledge of any discoverable matter. (b) It is...

  17. 49 CFR 386.38 - Scope of discovery.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... accordance with these rules, the parties may obtain discovery regarding any matter, not privileged, which is relevant to the subject matter involved in the proceeding, including the existence, description, nature... location of persons having knowledge of any discoverable matter. (b) It is not ground for objection that...

  18. 49 CFR 386.38 - Scope of discovery.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... accordance with these rules, the parties may obtain discovery regarding any matter, not privileged, which is relevant to the subject matter involved in the proceeding, including the existence, description, nature... location of persons having knowledge of any discoverable matter. (b) It is not ground for objection that...

  19. 29 CFR 18.14 - Scope of discovery.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... administrative law judge in accordance with these rules, the parties may obtain discovery regarding any matter, not privileged, which is relevant to the subject matter involved in the proceeding, including the... things and the identity and location of persons having knowledge of any discoverable matter. (b) It is...

  20. 16 CFR § 1025.31 - General provisions governing discovery.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...: (1) In general. Parties may obtain discovery regarding any matter, not privileged, which is within the Commission's statutory authority and is relevant to the subject matter involved in the proceedings... any discoverable matter. It is not ground for objection that the information sought will be...

  1. 49 CFR 386.38 - Scope of discovery.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... accordance with these rules, the parties may obtain discovery regarding any matter, not privileged, which is relevant to the subject matter involved in the proceeding, including the existence, description, nature... location of persons having knowledge of any discoverable matter. (b) It is not ground for objection that...

  2. 29 CFR 18.14 - Scope of discovery.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... administrative law judge in accordance with these rules, the parties may obtain discovery regarding any matter, not privileged, which is relevant to the subject matter involved in the proceeding, including the... things and the identity and location of persons having knowledge of any discoverable matter. (b) It is...

  3. 29 CFR 18.14 - Scope of discovery.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... administrative law judge in accordance with these rules, the parties may obtain discovery regarding any matter, not privileged, which is relevant to the subject matter involved in the proceeding, including the... things and the identity and location of persons having knowledge of any discoverable matter. (b) It is...

  4. 49 CFR 386.38 - Scope of discovery.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... accordance with these rules, the parties may obtain discovery regarding any matter, not privileged, which is relevant to the subject matter involved in the proceeding, including the existence, description, nature... location of persons having knowledge of any discoverable matter. (b) It is not ground for objection that...

  5. Perceptions of Student-Teacher Relationships, Self-Efficacy, and Subject Matter Retention in a Secondary Chemistry Course

    ERIC Educational Resources Information Center

    Bechtel, Michael Dean

    2012-01-01

    This was a study of students who had completed a chemistry course taught by one instructor in a large urban high school during 2009-2010. It was conducted in two phases: Phase One assessed self-efficacy, teaching practices, and subject matter retention taken 16 months after course completion. Phase Two consisted of a multiple-choice final exam…

  6. The Effect of Gender, Seniority and Subject Matter on the Perceptions of Organizational Justice of Teachers: A Meta-Analytical Study

    ERIC Educational Resources Information Center

    Altinkurt, Yahya; Yilmaz, Kursad; Karaman, Gizem

    2015-01-01

    This study reveals the results of a meta-analysis conducted with the theses and research studies published in Turkey from 2005 to 2012 regarding organizational justice. The purpose of this paper is to determine the effects of gender, seniority and subject matter on the perceptions of organizational justice of teachers. Specific criteria were used…

  7. Does Variation in the Extent of Generalized Trust, Individual Education and Extensiveness of Social Security Policies Matter for Maximization of Subjective Well-Being?

    ERIC Educational Resources Information Center

    Valeeva, Rania F.

    2016-01-01

    In this paper, I examine whether generalized trust and education, as well as social security policies of welfare state institutions matter for cross-national differences in subjective well-being (SWB), because knowledge on this issue is still lacking. For this purpose I integrated the insights of two sociological theories: Social Function…

  8. The Examination of Secondary Education Chemistry Curricula Published between 1957-2007 in Terms of the Dimensions of Rationale, Goals, and Subject-Matter

    ERIC Educational Resources Information Center

    Pekdag, Bulent; Erol, Hilal

    2013-01-01

    Fifteen secondary education chemistry curricula published from 1957 until 2007 were examined based on the dimensions of rationale, goals, and subject matter. An examination of documents in the scope of qualitative research was carried out in the study. The goals included in the examined chemistry curricula were analyzed according to the cognitive,…

  9. A Conflict in Your Head: An Exploration of Trainee Science Teachers' Subject Matter Knowledge Development and Its Impact on Teacher Self-Confidence

    ERIC Educational Resources Information Center

    Kind, Vanessa

    2009-01-01

    Teachers' subject matter knowledge (SMK) is one factor contributing to teaching 'successfully', as this provides a basis from which pedagogical content knowledge develops. UK-based trainee science teachers teach all sciences to age 14 and often up to age 16. Trainees have specialist science knowledge in chemistry, physics, or biology from their…

  10. The Place of Subject Matter Knowledge in Pedagogical Content Knowledge: A Case Study of South African Teachers Teaching the Amount of Substance and Chemical Equilibrium

    ERIC Educational Resources Information Center

    Rollnick, Marissa; Bennett, Judith; Rhemtula, Mariam; Dharsey, Nadine; Ndlovu, Thandi

    2008-01-01

    This paper presents two South African case studies designed to explore the influence of subject matter knowledge on pedagogical content knowledge (PCK). In the first case study on teaching the mole in two township schools, the findings illustrate that the participant teachers favoured procedural approaches at the expense of conceptual…

  11. What Subject Matter Knowledge Do Second-Level Teachers Need to Know to Teach Trigonometry? An Exploration and Case Study

    ERIC Educational Resources Information Center

    Walsh, Richard; Fitzmaurice, Olivia; O'Donoghue, John

    2017-01-01

    This study reports on the level of trigonometry Subject Matter Knowledge (SMK) of third and final-year pre-service second-level mathematics teachers () at an Irish third-level institution. The aim of the study was to determine if this sample of prospective teachers has an appropriate level of SMK to teach second-level trigonometric concepts. The…

  12. University Programme Preferences of High School Science Students in Singapore and Reasons That Matter in Their Preferences: A Rasch Analysis

    ERIC Educational Resources Information Center

    Oon, Pey-Tee; Subramaniam, R.

    2015-01-01

    This study explored an under-researched area in science education--the university programmes preferred by high school students who take physical science subjects and the reasons that matter in their preferences. A total of 1,071 upper secondary and pre-university students in Singapore, who take physical science subjects among their range of…

  13. A Case Study of Beginning Science Teachers' Subject Matter (SMK) and Pedagogical Content Knowledge (PCK) of Teaching Chemical Reaction in Turkey

    ERIC Educational Resources Information Center

    Usak, Muhammet; Ozden, Mustafa; Eilks, Ingo

    2011-01-01

    This paper describes a case study focusing on the subject matter knowledge, pedagogical content knowledge, and beliefs about science teaching of student teachers in Turkey at the start of their university education. The topic of interest was that of teaching chemical reactions in secondary chemistry education. A written test was developed which…

  14. The Effects of CLIL Education on the Subject Matter (Mathematics) and the Target Language (English)

    ERIC Educational Resources Information Center

    Ouazizi, Khalid

    2016-01-01

    This paper investigates the effects of Content and Language Integrated Learning, CLIL for short, on both the attainment of the subject matter, mathematics in our case, hence the content aspect of CLIL. The second axes of research focuses on the effect of CLIL on the learners' proficiency vis-à-vis the language of instruction, epitomized here by…

  15. Separation of β-amyloid binding and white matter uptake of 18F-flutemetamol using spectral analysis

    PubMed Central

    Heurling, Kerstin; Buckley, Christopher; Vandenberghe, Rik; Laere, Koen Van; Lubberink, Mark

    2015-01-01

    The kinetic components of the β-amyloid ligand 18F-flutemetamol binding in grey and white matter were investigated through spectral analysis, and a method developed for creation of parametric images separating grey and white matter uptake. Tracer uptake in grey and white matter and cerebellar cortex was analyzed through spectral analysis in six subjects, with (n=4) or without (n=2) apparent β-amyloid deposition, having undergone dynamic 18F-flutemetamol scanning with arterial blood sampling. The spectra were divided into three components: slow, intermediate and fast basis function rates. The contribution of each of the components to total volume of distribution (VT) was assessed for different tissue types. The slow component dominated in white matter (average 90%), had a higher contribution to grey matter VT in subjects with β-amyloid deposition (average 44%) than without (average 6%) and was absent in cerebellar cortex, attributing the slow component of 18F-flutemetamol uptake in grey matter to β-amyloid binding. Parametric images of voxel-based spectral analysis were created for VT, the slow component and images segmented based on the slow component contribution; confirming that grey matter and white matter uptake can be discriminated on voxel-level using a threshold for the contribution from the slow component to VT. PMID:26550542

  16. The median density of the Universe

    NASA Astrophysics Data System (ADS)

    Stücker, Jens; Busch, Philipp; White, Simon D. M.

    2018-03-01

    Despite the fact that the mean matter density of the universe has been measured to an accuracy of a few percent within the standard ΛCDM paradigm, its median density is not known even to order of magnitude. Typical points lie in low-density regions and are not part of a collapsed structure of any scale. Locally, the dark matter distribution is then simply a stretched version of that in the early universe. In this single-stream regime, the distribution of unsmoothed density is sensitive to the initial power spectrum on all scales, in particular on very small scales, and hence to the nature of the dark matter. It cannot be estimated reliably using conventional cosmological simulations because of the enormous dynamic range involved, but a suitable excursion set procedure can be used instead. For the Planck cosmological parameters, a 100 GeV WIMP, corresponding to a free-streaming mass ˜10-6M⊙, results in a median density of ˜4 × 10-3 in units of the mean density, whereas a 10 μeV axion with free-streaming mass ˜10-12M⊙ gives ˜3 × 10-3, and Warm Dark Matter with a (thermal relic) mass of 1 keV gives ˜8 × 10-2. In CDM (but not in WDM) universes, single-stream regions are predicted to be topologically isolated by the excursion set formalism. A test by direct N-Body simulations seems to confirm this prediction, although it is still subject to finite size and resolution effects. Unfortunately, it is unlikely that any of these properties is observable and so suitable for constraining the properties of dark matter.

  17. Severe retinopathy of prematurity predicts delayed white matter maturation and poorer neurodevelopment.

    PubMed

    Glass, Torin J A; Chau, Vann; Gardiner, Jane; Foong, Justin; Vinall, Jillian; Zwicker, Jill G; Grunau, Ruth E; Synnes, Anne; Poskitt, Kenneth J; Miller, Steven P

    2017-11-01

    To determine whether severe retinopathy of prematurity (ROP) is associated with (1) abnormal white matter maturation and (2) neurodevelopmental outcomes at 18 months' corrected age (CA) compared with neonates without severe ROP. We conducted a prospective longitudinal cohort of extremely preterm neonates born 24-28 weeks' gestational age recruited between 2006 and 2013 with brain MRIs obtained both early in life and at term-equivalent age. Severe ROP was defined as ROP treated with retinal laser photocoagulation. Using diffusion tensor imaging and tract-based spatial statistics (TBSS), white matter maturation was assessed by mean fractional anisotropy (FA) in seven predefined regions of interest. Neurodevelopmental outcomes were assessed with Bayley Scales of Infant and Toddler Development-III (Bayley-III) composite scores at 18 months' CA. Subjects were compared using Fisher's exact, Kruskal-Wallis and generalised estimating equations. Families were recruited from the neonatal intensive care unit at BC Women's Hospital. Of 98 extremely preterm neonates (median: 26.0 weeks) assessed locally for ROP, 19 (19%) had severe ROP and 83 (85%) were assessed at 18 months' CA. Severe ROP was associated with lower FA in the posterior white matter, and with decreased measures of brain maturation in the optic radiations, posterior limb of the internal capsule (PLIC) and external capsule on TBSS. Bayley-III cognitive and motor scores were lower in infants with severe ROP. Severe ROP is associated with maturational delay in the optic radiations, PLIC, external capsule and posterior white matter, housing the primary visual and motor pathways, and is associated with poorer cognitive and motor outcomes at 18 months' CA. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  18. 39 CFR 3.3 - Matters reserved for decision by the Board.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 39 Postal Service 1 2014-07-01 2014-07-01 false Matters reserved for decision by the Board. 3.3 Section 3.3 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE BOARD OF GOVERNORS (ARTICLE III) § 3.3 Matters reserved for decision by the Board. The following matters...

  19. 39 CFR 3.3 - Matters reserved for decision by the Board.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Matters reserved for decision by the Board. 3.3 Section 3.3 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE BOARD OF GOVERNORS (ARTICLE III) § 3.3 Matters reserved for decision by the Board. The following matters...

  20. 39 CFR 3.3 - Matters reserved for decision by the Board.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 39 Postal Service 1 2013-07-01 2013-07-01 false Matters reserved for decision by the Board. 3.3 Section 3.3 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE BOARD OF GOVERNORS (ARTICLE III) § 3.3 Matters reserved for decision by the Board. The following matters...

  1. 39 CFR 3.3 - Matters reserved for decision by the Board.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 39 Postal Service 1 2012-07-01 2012-07-01 false Matters reserved for decision by the Board. 3.3 Section 3.3 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE BOARD OF GOVERNORS (ARTICLE III) § 3.3 Matters reserved for decision by the Board. The following matters...

  2. White matter involvement in sporadic Creutzfeldt-Jakob disease

    PubMed Central

    Mandelli, Maria Luisa; DeArmond, Stephen J.; Hess, Christopher P.; Vitali, Paolo; Papinutto, Nico; Oehler, Abby; Miller, Bruce L.; Lobach, Irina V.; Bastianello, Stefano; Geschwind, Michael D.; Henry, Roland G.

    2014-01-01

    Sporadic Creutzfeldt-Jakob disease is considered primarily a disease of grey matter, although the extent of white matter involvement has not been well described. We used diffusion tensor imaging to study the white matter in sporadic Creutzfeldt-Jakob disease compared to healthy control subjects and to correlated magnetic resonance imaging findings with histopathology. Twenty-six patients with sporadic Creutzfeldt-Jakob disease and nine age- and gender-matched healthy control subjects underwent volumetric T1-weighted and diffusion tensor imaging. Six patients had post-mortem brain analysis available for assessment of neuropathological findings associated with prion disease. Parcellation of the subcortical white matter was performed on 3D T1-weighted volumes using Freesurfer. Diffusion tensor imaging maps were calculated and transformed to the 3D-T1 space; the average value for each diffusion metric was calculated in the total white matter and in regional volumes of interest. Tract-based spatial statistics analysis was also performed to investigate the deeper white matter tracts. There was a significant reduction of mean (P = 0.002), axial (P = 0.0003) and radial (P = 0.0134) diffusivities in the total white matter in sporadic Creutzfeldt-Jakob disease. Mean diffusivity was significantly lower in most white matter volumes of interest (P < 0.05, corrected for multiple comparisons), with a generally symmetric pattern of involvement in sporadic Creutzfeldt-Jakob disease. Mean diffusivity reduction reflected concomitant decrease of both axial and radial diffusivity, without appreciable changes in white matter anisotropy. Tract-based spatial statistics analysis showed significant reductions of mean diffusivity within the white matter of patients with sporadic Creutzfeldt-Jakob disease, mainly in the left hemisphere, with a strong trend (P = 0.06) towards reduced mean diffusivity in most of the white matter bilaterally. In contrast, by visual assessment there was no white matter abnormality either on T2-weighted or diffusion-weighted images. Widespread reduction in white matter mean diffusivity, however, was apparent visibly on the quantitative attenuation coefficient maps compared to healthy control subjects. Neuropathological analysis showed diffuse astrocytic gliosis and activated microglia in the white matter, rare prion deposition and subtle subcortical microvacuolization, and patchy foci of demyelination with no evident white matter axonal degeneration. Decreased mean diffusivity on attenuation coefficient maps might be associated with astrocytic gliosis. We show for the first time significant global reduced mean diffusivity within the white matter in sporadic Creutzfeldt-Jakob disease, suggesting possible primary involvement of the white matter, rather than changes secondary to neuronal degeneration/loss. PMID:25367029

  3. Understanding Physical Educators' Perceptions of Mattering Questionnaire--Physical Education

    ERIC Educational Resources Information Center

    Richards, K. Andrew R.; Gaudreault, Karen Lux; Woods, Amelia Mays

    2017-01-01

    Previous research has illustrated that physical educators feel their subject is valued less than others in the context of schools. However, to date, no instruments have been developed to measure physical education teachers' perceptions of mattering. This study sought to propose and validate the Perceived Mattering Questionnaire--Physical Education…

  4. 18 CFR 385.402 - Scope of discovery (Rule 402).

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Matters Set for Hearing Under Subpart E § 385.402 Scope of discovery (Rule 402). (a) General. Unless... Rule 410(c), participants may obtain discovery of any matter, not privileged, that is relevant to the subject matter of the pending proceeding, including the existence, description, nature, custody, condition...

  5. 18 CFR 385.402 - Scope of discovery (Rule 402).

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Matters Set for Hearing Under Subpart E § 385.402 Scope of discovery (Rule 402). (a) General. Unless... Rule 410(c), participants may obtain discovery of any matter, not privileged, that is relevant to the subject matter of the pending proceeding, including the existence, description, nature, custody, condition...

  6. 18 CFR 385.402 - Scope of discovery (Rule 402).

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Matters Set for Hearing Under Subpart E § 385.402 Scope of discovery (Rule 402). (a) General. Unless... Rule 410(c), participants may obtain discovery of any matter, not privileged, that is relevant to the subject matter of the pending proceeding, including the existence, description, nature, custody, condition...

  7. 18 CFR 385.402 - Scope of discovery (Rule 402).

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Matters Set for Hearing Under Subpart E § 385.402 Scope of discovery (Rule 402). (a) General. Unless... Rule 410(c), participants may obtain discovery of any matter, not privileged, that is relevant to the subject matter of the pending proceeding, including the existence, description, nature, custody, condition...

  8. 76 FR 79072 - New Standards for Domestic Mailing Services

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-21

    ... them are included in the applicable subject matter sections below. Changes for Letters Commercial First... Return Service. The maximum weight for machinable parcels that contain books or other printed matter... also will discontinue the 3-cent barcode discount for all Bound Printed Matter (BPM), Media Mail[supreg...

  9. Consequence of preterm birth in early adolescence: the role of language on auditory short-term memory.

    PubMed

    Fraello, David; Maller-Kesselman, Jill; Vohr, Betty; Katz, Karol H; Kesler, Shelli; Schneider, Karen; Reiss, Allan; Ment, Laura; Spann, Marisa N

    2011-06-01

    This study tested the hypothesis that preterm early adolescents' short-term memory is compromised when presented with increasingly complex verbal information and that associated neuroanatomical volumes would differ between preterm and term groups. Forty-nine preterm and 20 term subjects were evaluated at age 12 years with neuropsychological measures and magnetic resonance imaging (MRI). There were no differences between groups in simple short-term and working memory. Preterm subjects performed lower on learning and short-term memory tests that included increased verbal complexity. They had reduced right parietal, left temporal, and right temporal white matter volumes and greater bilateral frontal gray and right frontal white matter volumes. There was a positive association between complex working memory and the left hippocampus and frontal white matter in term subjects. While not correlated, memory scores and volumes of cortical regions known to subserve language and memory were reduced in preterm subjects. This study provides evidence of possible mechanisms for learning problems in former preterm infants.

  10. A Cross-Sectional Voxel-Based Morphometric Study of Age- and Sex-Related Changes in Gray Matter Volume in the Normal Aging Brain.

    PubMed

    Peng, Fei; Wang, Lixin; Geng, Zuojun; Zhu, Qingfeng; Song, Zhenhu

    2016-01-01

    The aim of the study was to carry out a cross-sectional study of 124 cognitively normal Chinese adults using the voxel-based morphometry approach to delineate age-related changes in the gray matter volume of regions of interest (ROI) in the brain and further analyze their correlation with age. One hundred twenty-four cognitively normal adults were divided into the young age group, the middle age group, and the old age group. Conventional magnetic resonance imaging was performed with the Achieva 3.0 T system. Structural images were processed using VBM8 and SPM8. Regions of interest were obtained by WFU PickAtlas and all realigned images were spatially normalized. Females showed significantly greater total gray matter volume than males (t = 4.81, P = 0.0000, false discovery rate corrected). Compared with young subjects, old-aged subjects showed extensive reduction in gray matter volumes in all ROIs examined except the occipital lobe. In young- and middle-aged subjects, female and male subjects showed significant difference in the right middle temporal gyrus, right superior temporal gyrus, left angular gyrus, right middle occipital lobe, left middle cingulate gyrus, and the pars triangularis of the right inferior frontal gyrus, suggesting an interaction between age and sex (P < 0.001, uncorrected). Logistic regression analysis revealed linear negative correlation between the total gray matter volume and age (R = 0.529, P < 0.001). Significant age-related differences are present in gray matter volume across multiple brain regions during aging. The VPM approach may provide an emerging paradigm in the normal aging brain that may help differentiate underlying normal neurobiological aging changes of specific brain regions from neurodegenerative impairments.

  11. 40 CFR 60.2720 - May I conduct performance testing less often?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... least 3 years, and all performance tests for the pollutant (particulate matter, hydrogen chloride, or...) If your CISWI unit continues to meet the emission limitation for particulate matter, hydrogen... shows a deviation from an emission limitation for particulate matter, hydrogen chloride, or opacity, you...

  12. Impaired memory is more closely associated with brain beta-amyloid than leukoaraiosis in hypertensive patients with cognitive symptoms.

    PubMed

    Smith, Eric E; Muzikansky, Alona; McCreary, Cheryl R; Batool, Saima; Viswanathan, Anand; Dickerson, Bradford C; Johnson, Keith; Greenberg, Steven M; Blacker, Deborah

    2018-01-01

    Hypertension is the strongest modifiable risk factor for subcortical ischemic changes and is also a risk factor for Alzheimer's dementia. We used neuroimaging to investigate the pathological basis of early cognitive symptoms in patients with hypertension. In this cross-sectional cohort study 67 patients age >60 years with hypertension and Clinical Dementia Rating scale score of 0.5 without dementia, and without history of symptomatic stroke, underwent MRI for measurement of subcortical vascular changes and positron emission tomography (PET) scan with Pittsburgh Compound B (PiB-PET) to detect beta-amyloid deposition. These imaging measures were related to neuropsychological tests of memory, executive function and processing speed. Mean age was 75.0 (standard deviation, SD, 7.3). Mean neuropsychological Z scores were: episodic memory -0.63 (SD 1.23), executive function -0.40 (SD 1.10), processing speed -0.24 (SD 0.88); 22 of the 67 subjects met criteria for mild cognitive impairment (MCI) and the remaining 45 subjects had subjective cognitive concerns only. In multivariable models adjusting for age and years of education, each 0.1 unit increase in mean cortical PiB-PET binding was associated with 0.14 lower mean Z score for episodic memory (95% CI -0.28 to -0.01). This means that for every 0.1 unit increase in mean cortical PiB-PET, episodic memory was 0.14 standard deviations lower. White matter hyperintensity volume, silent brain infarcts and microbleeds were not associated with neuropsychological test scores. Episodic memory was prominently affected in hypertensive participants with MCI or subjective cognitive concerns, and was associated with PiB-PET binding. This suggests a prominent role for Alzheimer pathology in cognitive impairment even in hypertensive participants at elevated risk for vascular cognitive impairment.

  13. [The contribution of legal medicine in child protection: Presentation of a multidisciplinary approach].

    PubMed

    Hiquet, J; Christin, E; Dubourg, O; Fougas, J; Baup, C; Brunet, G; Millington, J; Grosleron, N; Gromb-Monnoyeur, S

    2016-12-01

    Maltreatment is a complex issue and therefore, requires a multidisciplinary approach, which has been commonly used in North America since the 1980s but remains unsystematic in France. Since 1999, the Centre d'Accueil en Urgence des Victimes d'Agression (emergency unit for victims of assault) of the Bordeaux University Hospital has brought together various medical, paramedical, and social actors on this issue. A standardized psychosocial assessment procedure has been introduced and is detailed in this paper, and was consistently conducted in all cases of suspicion of abuse on a minor. The authors studied 74 cases of minors having undergone a psychosocial assessment following suspicions of maltreatment between 1 July 2014 and 30 June 2015 that were not referred to the courts. Forty-five girls and 29 boys, mean age 7 years, claiming mainly (75 %) to have been subjected to sexual violence, were addressed to us by internal partners (n=15) and external partners (n=37) and 22 who came to our unit by self-referral. Following our assessment, 35 returned to their home and 36 went to court following a police complaint (n=17) and a report filed to the public prosecutor of the Republic (n=19). Three of these cases were subjected to a report on matters of concern sent to the departmental council. Given the absence of a national consensus on the methodology used for assessing suspicions of maltreatment on minors, our psychosocial assessment can facilitate the task with its peer review as well as the detection and judicialization of the maltreatment. The authors also highlight the recent modification of article 226-14 of the Penal Code, which aims at protecting professionals reporting matters to legal authorities from any legal proceeding, except if it is established that the individual did not act in good faith. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  14. 78 FR 29158 - In the Matter of Zion Solutions, LLC; Zion Nuclear Power Station, Units 1 and 2; Order Approving...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-17

    ... NUCLEAR REGULATORY COMMISSION [NRC-2013-0096; Docket Nos. 50-295 and 50-304; License Nos. DPR-39 and DPR-48] In the Matter of Zion Solutions, LLC; Zion Nuclear Power Station, Units 1 and 2; Order Approving Indirect Transfer of Control of Facility Operating Licenses I. ZionSolutions, LLC (ZS) is the...

  15. 37 CFR 11.14 - Individuals who may practice before the Office in trademark and other non-patent matters.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Individuals who may practice before the Office in trademark and other non-patent matters. 11.14 Section 11.14 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE REPRESENTATION OF OTHERS BEFORE THE UNITED STATES PATENT AND...

  16. 78 FR 28245 - In the Matter of Southern Nuclear Operating Company, Farley Nuclear Plant, Units 1 and 2...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-14

    ... recent public examples, including those documented in EA-12-240 and EA-12-230, and the impacts when there... and EA-12-230, and the impacts when there is a loss of integrity and trustworthiness. f. By the later...-8; EA-12-145] In the Matter of Southern Nuclear Operating Company, Farley Nuclear Plant, Units 1 and...

  17. Bayesian Methods and Universal Darwinism

    NASA Astrophysics Data System (ADS)

    Campbell, John

    2009-12-01

    Bayesian methods since the time of Laplace have been understood by their practitioners as closely aligned to the scientific method. Indeed a recent Champion of Bayesian methods, E. T. Jaynes, titled his textbook on the subject Probability Theory: the Logic of Science. Many philosophers of science including Karl Popper and Donald Campbell have interpreted the evolution of Science as a Darwinian process consisting of a `copy with selective retention' algorithm abstracted from Darwin's theory of Natural Selection. Arguments are presented for an isomorphism between Bayesian Methods and Darwinian processes. Universal Darwinism, as the term has been developed by Richard Dawkins, Daniel Dennett and Susan Blackmore, is the collection of scientific theories which explain the creation and evolution of their subject matter as due to the Operation of Darwinian processes. These subject matters span the fields of atomic physics, chemistry, biology and the social sciences. The principle of Maximum Entropy states that Systems will evolve to states of highest entropy subject to the constraints of scientific law. This principle may be inverted to provide illumination as to the nature of scientific law. Our best cosmological theories suggest the universe contained much less complexity during the period shortly after the Big Bang than it does at present. The scientific subject matter of atomic physics, chemistry, biology and the social sciences has been created since that time. An explanation is proposed for the existence of this subject matter as due to the evolution of constraints in the form of adaptations imposed on Maximum Entropy. It is argued these adaptations were discovered and instantiated through the Operations of a succession of Darwinian processes.

  18. Fully-integrated framework for the segmentation and registration of the spinal cord white and gray matter.

    PubMed

    Dupont, Sara M; De Leener, Benjamin; Taso, Manuel; Le Troter, Arnaud; Nadeau, Sylvie; Stikov, Nikola; Callot, Virginie; Cohen-Adad, Julien

    2017-04-15

    The spinal cord white and gray matter can be affected by various pathologies such as multiple sclerosis, amyotrophic lateral sclerosis or trauma. Being able to precisely segment the white and gray matter could help with MR image analysis and hence be useful in further understanding these pathologies, and helping with diagnosis/prognosis and drug development. Up to date, white/gray matter segmentation has mostly been done manually, which is time consuming, induces a bias related to the rater and prevents large-scale multi-center studies. Recently, few methods have been proposed to automatically segment the spinal cord white and gray matter. However, no single method exists that combines the following criteria: (i) fully automatic, (ii) works on various MRI contrasts, (iii) robust towards pathology and (iv) freely available and open source. In this study we propose a multi-atlas based method for the segmentation of the spinal cord white and gray matter that addresses the previous limitations. Moreover, to study the spinal cord morphology, atlas-based approaches are increasingly used. These approaches rely on the registration of a spinal cord template to an MR image, however the registration usually doesn't take into account the spinal cord internal structure and thus lacks accuracy. In this study, we propose a new template registration framework that integrates the white and gray matter segmentation to account for the specific gray matter shape of each individual subject. Validation of segmentation was performed in 24 healthy subjects using T 2 * -weighted images, in 8 healthy subjects using diffusion weighted images (exhibiting inverted white-to-gray matter contrast compared to T 2 *-weighted), and in 5 patients with spinal cord injury. The template registration was validated in 24 subjects using T 2 *-weighted data. Results of automatic segmentation on T 2 *-weighted images was in close correspondence with the manual segmentation (Dice coefficient in the white/gray matter of 0.91/0.71 respectively). Similarly, good results were obtained in data with inverted contrast (diffusion-weighted image) and in patients. When compared to the classical template registration framework, the proposed framework that accounts for gray matter shape significantly improved the quality of the registration (comparing Dice coefficient in gray matter: p=9.5×10 -6 ). While further validation is needed to show the benefits of the new registration framework in large cohorts and in a variety of patients, this study provides a fully-integrated tool for quantitative assessment of white/gray matter morphometry and template-based analysis. All the proposed methods are implemented in the Spinal Cord Toolbox (SCT), an open-source software for processing spinal cord multi-parametric MRI data. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. FACTORS INFLUENCING PHOTOREACTIONS OF DISSOLVED ORGANIC MATTER IN A COASTAL RIVER OF THE SOUTHEASTERN UNITED STATES

    EPA Science Inventory

    Photoreactions of dissolved organic matter can affect the oxidizing capacity, nutrient dynamics, trace gas exchange, and color of surface waters. This study focuses on factors that affect the photoreactions of the colored dissolved organic matter (CDOM) in the Satilla River, a co...

  20. 37 CFR 2.122 - Matters in evidence.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Matters in evidence. 2.122 Section 2.122 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE RULES OF PRACTICE IN TRADEMARK CASES Procedure in Inter Partes Proceedings § 2.122 Matters in...

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